LOCUS       DAFBVQ010000001       113870 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.001, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000001 DAFBVQ010000000
VERSION     DAFBVQ010000001.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 113870)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 113870)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..113870
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.001"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(19..729)
                     /locus_tag="LLC22_000001"
     CDS             complement(19..729)
                     /locus_tag="LLC22_000001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4811 domain-containing protein"
                     /protein_id="HBK5433314.1"
                     /translation="MIIGVLIVSLLAFALTNVFAKKTWQTFLSLIFGLIFVASLSLIV
                     ANLSNHFGMEKVTETKTEKIVSSADSQGADMLLYKALGNGKEKVYLYRTNEKQEKPKA
                     TGTDNETNKVEKTDGDAEKVTKTTYWEYKNDMYKFWFNIADNNHEYDSRVNTFKIPET
                     WVELSTDQAAKLAELVKKQQSTMESEAKAYVQDGMVKAMTENPKMSKAEQEQRTKALA
                     AEFQQQAFAKLVKEAKGE"
     gene            complement(726..2198)
                     /locus_tag="LLC22_000002"
     CDS             complement(726..2198)
                     /locus_tag="LLC22_000002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008269079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBK5433315.1"
                     /translation="MSNNQPVDIYGKPYNRTLLVVVLLIGTFCTVLNQTLLTTAFPTL
                     MKAFDISASDVQWLTTGFLLVNGIMIPITAWLINKFSSRNLYLSAMTIFLIGTITCFT
                     APNFSTLLIGRLIQACGVGVSMPLLQNIMLSIFPPEKRGSAMGMSGIVIGLAPALGPT
                     LSGYIIDNYHWRDLFGMVLPIVVLVLVLAFFLMKSVIPLSNPSIDILSAILSTIGFGS
                     LLYGFSSVGDDGWGSLKVIGFLVVGVIFIALFSWRQLHLEHPFLELRVFKSSTFTIAA
                     VLAGVTNMAMVGAEMVVPLYIQNIRGESAFHSGLMLLPGALIMGAMMPVTGAIFDKYG
                     AKRLAITGMFILTAATAPFAFLTKTTPVLYIVILYAIRMFGISMVMMPVTTSGMNALP
                     NNLISHGTAVNNTFRQIASSIGTAILISVLTNVTKANIPSKSVLDNTPLAYKDQAINA
                     TLSGYHAAFIVAIIFGILGFIIAFLLKKKEPVLMKAGDNA"
     gene            2336..2809
                     /locus_tag="LLC22_000003"
     CDS             2336..2809
                     /locus_tag="LLC22_000003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5433316.1"
                     /translation="MVGASLKRLLENDQLVVGISELSDIVGVSPRQLRYWEQKGFIRS
                     IEADANCPRKYRLPTVIKVELIKKYLDDGFTLSKAAEKAEIRQKKMHHVRKVFSKAIK
                     DIELIDERYTILQIGNFKEENAKMYIIHDNETDELTYKLLPVDEKADYEQLLKEL"
     gene            complement(2962..3513)
                     /locus_tag="LLC22_000004"
     CDS             complement(2962..3513)
                     /locus_tag="LLC22_000004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5433317.1"
                     /translation="MARKNTLRYILLGLLSKKKMTGYELNQSFKNEIGEFWQAKHSQI
                     YPELAKMEEQGIIQHQVEITGEKLEKKVYELTEEGKEQLAEWIHTPTNELPVNRDEFV
                     LKLYFVKDVNDPALVEIIQQQRDLHEEKRLHLLERKKTIFPTEKEKHENYGHYLILAH
                     AINRETEYANWLTDVLEESNRKK"
     gene            3618..4148
                     /locus_tag="LLC22_000005"
     CDS             3618..4148
                     /locus_tag="LLC22_000005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307921.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenolic acid decarboxylase"
                     /protein_id="HBK5433318.1"
                     /translation="MKEFKELEDFIGTHFIYTYDNGWEYEWYAKNDHTVDYRIHGGMV
                     KGRWVKDQEADIVKLTDGVFKITWTEPTGTDVALDFMPNEKKLHGMIFFPKWVEEHPE
                     ITVTFQNEHIAEMEAAREKYETYPKLLVPEFATITYMGDAGIDNEDVISEEPYDGMPD
                     DIRSGKYFDENYKRVK"
     gene            complement(4631..5074)
                     /locus_tag="LLC22_000006"
     CDS             complement(4631..5074)
                     /locus_tag="LLC22_000006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5433319.1"
                     /translation="MIRTTTKLSAKELESVLSIWLHANLDSHEFIPSTYWENQVESVR
                     KALPDAVIYLAEIDQEIIGFAGVIDQFIAGIFVKREYRQQRIGTQLMKKIKETNKTLT
                     LTVYQKNQSAIHFYLSQGFTIQTQQKDEAVNEEELVMKWNQNADF"
     gene            complement(5090..6250)
                     /locus_tag="LLC22_000007"
     CDS             complement(5090..6250)
                     /locus_tag="LLC22_000007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5433320.1"
                     /translation="MKQSKQKQSRRLLFRLFLLICIVVGLLIALYPFYVDSLNSFIDQ
                     KRIEQVQKRTAAEIEVQRKKMEEKNQRLTDQGFNPGTDPFNEKNRNESTTSSQLEEWL
                     IGSINIPKIQLNISLYDRLNGRILENGAGVLQGTSFPLGGNSTHSVISAHSGLPNRRL
                     FTELDRLENGDTFILTVLGEKLAYQVKNIQVVLPDDTSVLTISEGEDLVTLLTCTPYM
                     INTHRLLVTGHRIPYNESVKKEEGKGNQERTMRQWFILAGTIIAVVILLVFIGRLIYQ
                     YRLSKKVLDFSFIISDSSGKPVNGSSFILKHKKKTLTRNGVPFSVQSDHHGKVKLDQL
                     PGGTYRIVSADDPKVAVSFGIRKVKQEKIYFFEGRKLVKELQKNGFYFKINE"
     gene            6757..8457
                     /locus_tag="LLC22_000008"
     CDS             6757..8457
                     /locus_tag="LLC22_000008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433321.1"
                     /translation="MMNLSKVCKGVRQLKKYGPFLAIFFIALAFLMPHLFTHKLILGA
                     DAPFHYNRFYDAAQQIKYGDFHYFPSLYGFQQSGRIVNAVYGPFFAYLQGLIVLLAGS
                     WFHYQILSNFILYLISGFSMLILLRYVNVRNWVSVPVAVLFMSTYSIQYWSINQGFTS
                     WGTCFYPLCMIPIADFVLHKKFPVIKVAVSVGLMTQIHLLSSIMLALMYIPFYLYYFF
                     NQTEKGKALLQLIKSVLLYFVLTANIWAGLAIVYSGNKILPPFVNREMSQKAIDLDGS
                     YWLHYPKAFPILILSGFLLFIFFQQKNTLFQKIVLYTSLVFFFLSTSLIPWTTLIEKN
                     VPFISLIQFPFRFFVPFTLLLLLYLALSLNQWSEQKWFRLLSIFGILIFSAQTIQNLY
                     QHLEKWENETFVSRHTYLFDTPEEARKTFFSKDMSTSLFVFQKTTPDYLPIYKETKDN
                     KYDRYNEEILENETTFIKTHPGGLLTIKWKNTGDKTVHIPVIVYDRTVLQQNGKTLTD
                     YEVTDIGTPIVKQQKGINELTLHYQTPIYFYFILSLTLIGWFTLLCLFIYHRYKLLRA
                     "
     gene            complement(8559..9392)
                     /locus_tag="LLC22_000009"
     CDS             complement(8559..9392)
                     /locus_tag="LLC22_000009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease/exonuclease/phosphatase family
                     protein"
                     /protein_id="HBK5433322.1"
                     /translation="MKFMTLNTHSWLEPEPEKKLQELADKILLEDYEVIALQEINQLL
                     ESEEVEPAKLMKFCPVKNQVPIRKDNFAYRLVQLLKEHGKEYFWSWEMSHIGYDKYEE
                     GNALLTKKTLESQVLTVSQFQKKEDYQTRKILIGKTKIDDQDIFVSSCHFSWWTDKKS
                     GFYFEWKNLENYFLETRVPLFFLGDFNNPVDSQGYYTVRESCLLLQDSYVVANEKGKA
                     ATVEKKIDGWEQNTEKLRIDFIFVPEGMQVKKYQRIFDGIDSPIISDHYGVEIELDVN
                     E"
     gene            complement(9696..11861)
                     /locus_tag="LLC22_000010"
     CDS             complement(9696..11861)
                     /locus_tag="LLC22_000010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5433323.1"
                     /translation="MKKIFSFEFWQKFGKALMVVVAVMPAAGLMISIGKSIPLINPDW
                     TPLVTTGGVIENIGWAIIGNLHILFALAIGGSWAKERAGGAFAAGISFILINRITGAI
                     FGVTSDMLANEDAFTHTLFGTKIMVKGFFTSVLEAPALNMGVFVGIIAGFVGAMAYNK
                     YYNYRKLPDALSFFNGKRFVPFVVILWSTIVALILAVVWPNVQAGINNFGLWIAESQE
                     SAPILAPFLFGTLERLLLPFGLHHMLTIPINYTQLGGSYEILSGAQAGTQVFGQDPLW
                     LAWATDLVNLKGAGDMSQYEFVLHNWTPARFKVGQMIGSSGILMGMAFAMYRNVDPDK
                     KARYKSMYFSAALAVFLTGVTEPLEFMFMFAAVPLYVIYSVIQGAAFAMADILPLRVH
                     SFGNIELLTRTPLAIKAGLGGDLINFVLCVIAFGVVTYFLANFLIKKFNFATPGRNGN
                     YDNDSEETVVSNSGTGTADQQVVQIIHLLGGKENIKDVDACMTRLRVSVNDREKVGTE
                     EAWKRAGAMGLIVKDNGVQAVYGPKADVLKSDIEDLLQSGAEIPEPEMVSTGNGQAGS
                     KQYLGIEQELVSAASGEVIPLSEVKDPVFSQKMMGDGFAVIPTSREVVAPIAGKVTSI
                     FPSKHAIGLETKDGIEVLIHMGIDTVQMNQPAFEIAVKEGQEVGTGTKLAEMDLDVIQ
                     NEEKDPTIMIVFTNDKVEEVVIKQLGTVTAGKVIGSIKM"
     gene            12121..14415
                     /locus_tag="LLC22_000011"
     CDS             12121..14415
                     /locus_tag="LLC22_000011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBK5433324.1"
                     /translation="MKQIKRLFAIDPWKISTTQLDKKNLRLQESLTSIGNGYMGMRGN
                     FEETYSGDHHQGTYLAGVWYPDKTRVGWWKNGYPEYFGKVINALNFIAIDISINDQLI
                     DLASLEPEDFYWELDMKNGVLSRTFTITTSTNKVRISFERFLSIVKKESAYIYLTIEM
                     LEGSGTVKLVSKLDGNVQNEDSNYDEHFWNEIDRGTIEEIGYLTTKTIPNNFGIEQFT
                     VTAAMRHFVNGKSVIPDYHEDTLALHGCLSAELSQGETWSVEKEIIVLTSRDIPEAQQ
                     AEKAVSELTNQTNNYIQAKEEQTAAWAERWKLADVVIEGDEEAQQGIRFNLFQLFSTY
                     YGEDERLNIGPKGFTGEKYGGATYWDTEAYAVPLYLALAKPEVTKNLLKYRHNQLPQA
                     IHNAQQQGLKGALYPMVTFTGVECHNEWEITFEEIHRNGAIAYAIYNYTNYTGDTEYL
                     KNEGLEVLAEIARFWADRVHFSKRANKYMIHGVTGPNEYENNINNNWYTNTIAAWVLR
                     YTRENYLTYQKEAAITISEEELAKWKDIAENMYFPVDEELGIFVQHDTFLDKDLMPVS
                     DIPTSDLPLNQHWSWDKILRSCFIKQADVLQGIYFFNDTFTKEEKQKNFDFYEPMTVH
                     ESSLSPSIHSILAAELGMESKAVEMYQRTARLDLDNYNNDTEDGLHITSMTGSWLSIV
                     QGFAQMKTAHDQLRFAPFLPKTWKAYSFHINYRGRLLFISVTDEQVTFKLLEGSPLEI
                     YVYEQSYSLADRLEITLRKEEANV"
     gene            14408..15073
                     /gene="pgmB"
                     /locus_tag="LLC22_000012"
     CDS             14408..15073
                     /gene="pgmB"
                     /locus_tag="LLC22_000012"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBK5433325.1"
                     /translation="MFKGVLFDLDGVITDTAEFHYRAWRKLGQEIGITIDHTFNEQLK
                     GVSREDSLSLLLAYGGKEHSFTKEEFAELAKRKNDYYLEMIQTIEPKDVFPGVVPLLD
                     SLKEEKIKIALASASKNGPFLLEKMGLTPYFDAIADPAEATNGKPAPDIFLLAAKAVG
                     LKAEECIGIEDAQAGIQAILSSGAQPIGVGRAEDLGEEIPLVPDTTFLTIDYLKEKWH
                     DHG"
     gene            15066..16073
                     /locus_tag="LLC22_000013"
     CDS             15066..16073
                     /locus_tag="LLC22_000013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBK5433326.1"
                     /translation="MDNPEISVVPVPETEIKKITLKNDYLEVVLLNYGARLHQIFAPD
                     KEGKSENVLLSYDRFEDVLTDKSFFGATVGPVAGRIRDASWGEHRLEKNCGSHHIHGG
                     TKGWSFQFWEVEVFKTPSSIGVVFYLKDEFSTYPGPITATITYRLTKNELEMTTSASS
                     LVETICNPTNHAYFNLSGNGTRDIYEHQLTVFLDGVLELDQEKLPTGNWTKKEKLPID
                     FRKSPTLQEILACYPDGLDDVFLLHHPRLSKTSLQLFEKHSGRQMTIATSNKSMVLFS
                     TTGFEADFSVNGKQMHSNYGLAIEPQEIPDIVHFPKFGSINLHPGQERISQTIYRFSA
                     Q"
     gene            16095..17114
                     /locus_tag="LLC22_000014"
     CDS             16095..17114
                     /locus_tag="LLC22_000014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5433327.1"
                     /translation="MAITVKDVAKKAGVATSTVSRVINDHPSISETTKKKVRKIMDEL
                     GYVPNMTARNLGKRISSAIGVILPPLDSKERIGNPFYLEIMEAINEEARNYDMTTAIA
                     TAKNFELLLENVQRMHLQKQVDGFILVYSDSQDTVIDYLYQNHIPFTLIGQPYHHENE
                     IVYVDNDNQLLGKQATEFLIQNGHKNILFVTNTTHESLYFERYFGYQKAMMMAGLPAL
                     SSVVLEHPEDYLSFEKTLKENEATALVVIDDIFALRTMQLAQMYGYVIPETLSVISFN
                     NSIFSTLTHPYLTSIDIDISELGRVAMQKLRELIHEELSSGVRLVIPHRLIKRETVVP
                     LENPY"
     gene            complement(17395..18763)
                     /gene="nhaC"
                     /locus_tag="LLC22_000015"
                     /pseudo
     CDS             complement(17395..18763)
                     /gene="nhaC"
                     /locus_tag="LLC22_000015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
     gene            complement(18872..20293)
                     /locus_tag="LLC22_000016"
     CDS             complement(18872..20293)
                     /locus_tag="LLC22_000016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5433328.1"
                     /translation="MSKSEVSKMGLGTFIGLTMALCATVRSIPTLAAVGWTLIFYSIF
                     AVLFFAGPISMVSGELSTMLPQEGGPQLWVKTALGSKWGFVVAWLLWVQMFPGMVMVA
                     STLGPLLGNTFGNVELGNNHWFVLGCILVIYWIITILNLKFDMAKVGGNIGVWLGVYI
                     PVVIMFVLGVLAAFKVGLVSNGYLGDFSWSKAFPDLEHIDSLKYLAGITFIFVGIEMS
                     SVYMPRLKDATKNYTKGVFIALIGLVLLNVINAMLVANVVPDGKMELANITQPILIDC
                     QILGLPEVIGNIFSFMVFIGVLLQLSAWVTGPSKTIIQVAREGFLPPKFGFHKENKYG
                     VSRNVVLTQSIVISLFALLYGVMDDVSAVFLTLTNATTVIYCIVYILIAVSLLKMRKK
                     HPEFERPYRIGKNGNGLAWVVSCMLIFSIIVVVFATLGTATLSDALLVAAITVVMFVI
                     PLIINHFKKDSWGIEVEKSLEEK"
     gene            complement(20536..22413)
                     /gene="tdc"
                     /locus_tag="LLC22_000017"
     CDS             complement(20536..22413)
                     /gene="tdc"
                     /locus_tag="LLC22_000017"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBK5433329.1"
                     /translation="MSESLSKDLNLNALFIGDKAENGQIYKALLNELVDEHLGWRQNY
                     MPQDMPIITPEEKSSASFEHTVNKTKDVLSEISARMRTHSVPWHNAGRYWGHMNSETL
                     MPSLLAYNFAMLWNGNNVAYESSPATSQMEEEVGMEFAKLMSYKDGWGHIVADGSLAN
                     LEGLWYARNIKSLPLAMKEVTPELVAGKSDWELMNLSTEEIMNLLDSVPEKIDEIKAH
                     SARSGKHLEKLGKWLVPQTKHYSWLKAADIIGIGLDQVIPVPVDHNYRMDINELEKIV
                     RGLAAEKTPILGVVGVVGSTEEGAIDGIDKIVALRRVLEKDGIYFYLHVDAAYGGYGR
                     AIFLDEDNNFIPFEDLKDVHYKYNVFTENKDYILEEVHSAYKAIEEAESVTIDPHKMG
                     YVPYSAGGIVIKDIRMRDVISYFATYVFEKGADIPALLGAYILEGSKAGATAASVWAA
                     HHVLPLNVTGYGKLMGASIEGAHRFYNFLNDLSFKVGDKEIEVHPLTYPDFNMVDYVF
                     KEKGNDDLVAMNKLNHDVYDYSSYVKGSIYGNEFLTSHTDFAIPDYGNSPLQFVNQLG
                     FSDEEWNRAGKVTVLRASVMTPYMNKEEHFEEYAEKIKAALQEKLEKIYADQLLASEA
                     K"
     gene            complement(22704..23960)
                     /locus_tag="LLC22_000018"
     CDS             complement(22704..23960)
                     /locus_tag="LLC22_000018"
                     /EC_number="6.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine--tRNA ligase"
                     /protein_id="HBK5433330.1"
                     /translation="MNIIDELTWRDAINQQTNEERLRELVEEKSISLYCGVDPTGDSM
                     HIGHLIPFMMMKRFQLAGHHPYILIGGGTGTIGDPSGRKTERVLQTMEQVQHNVDALS
                     NQMRKLFGKDANITFVNNYDWLSKISLLEFLRDYGKNFNINTMLAKDIVASRLEVGIS
                     FTEFTYQILQSIDFLHLHKTYDVQLQIGGADQWGNITAGLDLIRKLEGPEAEAFGLTI
                     PLMLKADGTKFGKTAGGAVWLDPKKTSPFEFYQFWLNQDDRDVVKYLKFFTFLSQEEI
                     EDLAKKVETEPEKREAQRRLAEEVTRFVHSEEDLKEAQKITQALFSGNIKELNAEEIA
                     QGFGKMPNVEISSTPENIVELLVSTKIEPSKRQAREDVSNGAISINGDRVTDLNFVIN
                     PSDEFDGKFVVIRKGKKNYFLAKVID"
     misc_binding    complement(24072..24277)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            24540..25841
                     /locus_tag="LLC22_000019"
     CDS             24540..25841
                     /locus_tag="LLC22_000019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
                     /protein_id="HBK5433331.1"
                     /translation="MEKKQKIILGATSALTIVILILSLFFVIRSSTKKEPIIPEKKIT
                     EKAKEPTDDKQQLVTQAKNLAQSYDYDQAIALLEKDSKNGSTETQQLLQTLKKEKEQL
                     IDWSDPTQISHVFFHSLIVDPQKAFHSQQAQGYKDYMVTVEEFNRSIEQLYQNDFVLV
                     NLNDLIQKDEQGNLSFNGLALPEGKKPLVLSQDDVSYYEYMDNSGFPSRLVVSNNNEI
                     KNVYKEKDKEEIGDFDMVPLIDAFVKKHPDFSYRGAKGTLALTGYNGVLGYRTSKSQY
                     GDNEKTKKEIKEAKKVAEQLKKDGWSFASHTWGHLNMTQASLEDVKKDNELWQQEVAP
                     ILGKTNILIYPFGADISDWQPYSAENQKFAYLKSQGFDIFCNVDASTPAWGQLGTDFY
                     RNARINIDGIRFQSDLDGKNPILDPFINVHDVYDKEARESA"
     gene            complement(25910..26509)
                     /locus_tag="LLC22_000020"
     CDS             complement(25910..26509)
                     /locus_tag="LLC22_000020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5433332.1"
                     /translation="MNGFEKRAQEKKKEILQAAFDLMNTDIGTAGVTMDKVAENAQVS
                     KATIFKYFGSKEGLIYEVFFAFMNDLGQEAKALIAENLPFEETLIAMSENKIRYLNRV
                     NKQFYIDLMTYYTKKEKKEFSDAMDAYTQESFSIMLDLFHRGRKEGKVDLKYSDEFLI
                     LYFQAMVEGISKPEIYAKLLPYTAEWTEVLIKGIAPKKK"
     gene            26763..27644
                     /locus_tag="LLC22_000021"
     CDS             26763..27644
                     /locus_tag="LLC22_000021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310716.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5433333.1"
                     /translation="MAEIVKVTHLKKSFGRFEALKDVSFTVHSGEVVGFIGPNGSGKS
                     TTIRTLLGIIKKDGGTATIFGQDVWEDSLSIHERLSYVPGDISLWGNLTGGAIIDLFM
                     KLHGKGSAQKKDELIQRFSLDPKKKAKNYSKGNRQKVGLIAALAVDSDLYLFDEPTSG
                     LDPLMETIFQEEVEKLKEQGKSILLSSHILSEVERLADKVVIIREGTLDEEGTLDELR
                     HLTRSTITIETEAENSHLAQLNGVHDFVQKGHLAQFAADNEAFDVILAEASKLGVKKF
                     ESIPPTLEDLFMRHYEG"
     gene            27657..29267
                     /locus_tag="LLC22_000022"
     CDS             27657..29267
                     /locus_tag="LLC22_000022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetronasin resistance protein"
                     /protein_id="HBK5433334.1"
                     /translation="MTDKFSRWSTLFSQNLSRDWKKILIWLVGVTAFSGGFVPAFEEL
                     TSGQGLAGLYETLQNPAMIAMVGPTPASNAAEYTLGAMYANEMLLFCSLFAAVISVLH
                     VVSQTRKKEELGLIELIRSFRVGRQANSLAVIAESILINLLLAISISCTMIFFQADSI
                     TAEGAWLFGLSVGSMGILGSAVALFAAQLMPSSASSNGLSLAFLGGLYLLRAITDVAD
                     SSLSMWNPLGWSYLTYPFTTNNWIPLLYLFLFSLILIISSFVLEEHRDLNTGYIPERE
                     GKPYAKRSLLSLRGLLFYLNKGMTISWLITFGLMGAAYGSIYGNMQQFLESNDLMKQM
                     FIQSGVSIEKNFTSTIMVVLICLAAILPIASINRLFTEETHGRMNQLFATKISRNQLY
                     WTNMLLAILFAILAILISSGALGLSALASMKDAKDMDLLMFLKAGFNFLPAVLVFIGI
                     SGFLFGWLPRIGKLAYIYLAYSFALNYFGGILDLPEWFSKTAVPSWVPRMPNDSFDLS
                     VFLTLSCISLALFVLGSIGYRRRDLLEG"
     gene            complement(29344..30003)
                     /locus_tag="LLC22_000023"
     CDS             complement(29344..30003)
                     /locus_tag="LLC22_000023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK5433335.1"
                     /translation="MSHDHLCVSFVPLFNHLVQQDQEKVHALVKHHYVEKGEQILAPN
                     GEPQLVIVASGSMKVYQLSASGKEQLLRVIEPGGYEGESQLLGVPNESLFGEALEKTE
                     ICILRQKDFSELLLHYPALSLKLLAINVEKLTKVQQQTTFLMMEKVEERVAVYLLDLA
                     KATGKDHFFLPMKMKELAAFIGTTPETLSRKFKLLEENGYVKRKNREVWIIDKEQLED
                     L"
     gene            complement(30286..30951)
                     /locus_tag="LLC22_000024"
     CDS             complement(30286..30951)
                     /locus_tag="LLC22_000024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate 1-dehydrogenase family
                     protein"
                     /protein_id="HBK5433336.1"
                     /translation="MELGKSDYQLFDRPIYAFKQLKESHPTDKIEQIKKEYKEHWQKW
                     KEIQLQTAALLPDMYGMSKPKIESWTNGWNLRSHFWSAYRSESRQDENACLAVLLNQK
                     QYQIYLMYQHYKSEERYGSIAAYNQLLAILKEWSKTVDIKDYYIWPQPEHELDDHLAL
                     SDYLSDTKKQEELKKAMRDRTFQMGKLFFYPQEIEHVEQITAETLQELAPLYQKLGAE
                     KFQ"
     gene            complement(31098..31703)
                     /gene="dhaL"
                     /locus_tag="LLC22_000025"
     CDS             complement(31098..31703)
                     /gene="dhaL"
                     /locus_tag="LLC22_000025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit L"
                     /protein_id="HBK5433337.1"
                     /translation="MKLTVQEIQEWLTQFAEAINQNKQYLSDLDTPIGDGDHGNNMGR
                     GVSAYEEAFQADHPETISDTFKVFSMAMISKVGGASGPLYGSAFMNMMKATKEVDSID
                     SQEKLGEVIEQGTAGIQSRGKAEADDKTMLDVWLPVTEALKAGNLTKEIIDQAKEHTK
                     VLVAKKGRASYLGERAIGHIDPGAASSAILFSTLLDVINQP"
     gene            complement(31731..32741)
                     /gene="dhaK"
                     /locus_tag="LLC22_000026"
     CDS             complement(31731..32741)
                     /gene="dhaK"
                     /locus_tag="LLC22_000026"
                     /EC_number="2.7.1.121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroxyacetone kinase subunit DhaK"
                     /protein_id="HBK5433338.1"
                     /translation="MPERKDGNKLKKIMNDPSNIVEEMLEGLVKSYPELVHRVESSRV
                     VAKNQKAEQVGLVSGGGSGHEPSHAGFVGEGMLSAAVLGDVFTSPTPDQIQTAIKEAD
                     SGKGVLLIVKNYTGDALNFDMAKELAAMDDIEVESVIVDDDIAVENSTYTAGKRGVAG
                     TVLVHKIVGDAARNGASLAELKELGEKVVQATKTIGLALRAATVPEVGKPGFELGEDE
                     IEYGVGIHGEPGYRREKMQPSKVLAKELVTKILDDYSNLPKEAGVLVNGMGGTPLMEQ
                     FVFMNDVLALLEERGVNVVFRKVGNFMTSLDMQGLSLTLIDLTETQWKDSLESNVQTI
                     SW"
     gene            complement(32716..33162)
                     /gene="dhaM"
                     /locus_tag="LLC22_000027"
     CDS             complement(32716..33162)
                     /gene="dhaM"
                     /locus_tag="LLC22_000027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS-dependent dihydroxyacetone kinase
                     phosphotransferase subunit DhaM"
                     /protein_id="HBK5433339.1"
                     /translation="MKAKPIVSNYVKERKILVKKSILLISHSQKVTDGIKEMIEQMQK
                     SEEVQIFSLGGINGEIGSDPMKIVEAVNESSDAASYFVFADIGSAVLNSELAKDMLEE
                     EQQQRYHLVDAPLVEGAFAAAITAGITDDTQQILTEAQNAGKKGWE"
     gene            33265..33585
                     /locus_tag="LLC22_000028"
     CDS             33265..33585
                     /locus_tag="LLC22_000028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal-binding domain-containing protein"
                     /protein_id="HBK5433340.1"
                     /translation="MITTTTNSVEGKAVVAYKGIVFGEVITGIHAFKDLEAGLRNIFG
                     GRSKSYENELMGAREEALAEMAERAKALGADAIIGVKMDYEVLGSDNGMLMVTCSGTA
                     VSTR"
     gene            complement(33697..34566)
                     /locus_tag="LLC22_000029"
     CDS             complement(33697..34566)
                     /locus_tag="LLC22_000029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5433341.1"
                     /translation="MGKVMKKRMKPLIWPIAVSSIFLLGQTAFAETSEPAQTEPSTTI
                     SSSGAENGASETEMTSNVPTDNSGETISSSEDTSINSSTSSDQIDHLQDLENKRKELE
                     EALEAAKNKLKEDQAAIDQDLADLKNKVGNDRAQLEKKLAEAKAKAEAVQTDLDGKIQ
                     QAKEFNQQLNQVAQTASGKLSQTQADITAASQAIHGKISEAQTVANDFEAKKADLAAS
                     FQRIKDILHSAGEKSVTSGSTTETVQQTTEPSKSTSQTLPKTNEKTASVSYSLAGAGV
                     LVAAAYGIIRKKK"
     gene            complement(34662..35966)
                     /locus_tag="LLC22_000030"
     CDS             complement(34662..35966)
                     /locus_tag="LLC22_000030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319539.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5433342.1"
                     /translation="MISITHTGNLFLDTCLSIMYFFLVSYPILGGFVWFIGVWCYVFL
                     YKHKQKEWVDVPLSVEPFITIMVPAHNEEIVIEYTIEYLMTKLNYHNYEVLVTDDGST
                     DQTPEILARLMKKYANLRVVRIEKNKGKAHAFNIGLAFAKGKLILSNDADTVPEPDAL
                     IRYVNYFIRPGARHIAAVTANMDVQNRTKLIAKSQTVEFSSIVGIIKRTQSAVFGGLY
                     AYSGANTMYRKEALIDVGGFRQDRATEDISIAWDHQLNDWLSVFAPEIIFFMEVPVTL
                     KMLYRHRKRWAKGGTEVWLTNFKKVMLHPFKHIGRTIIFIDQTLSIVWSIFFCISVVL
                     FAGLIGHYVYQGNYEQIYITFTFSFVFICFEMVAGFFQLLASLIVDDRRRKLKYLLFA
                     PLYMLLFWIVNAITIVTTFIPAVKTILGYGSGTWKSPERTKK"
     gene            complement(35963..36472)
                     /locus_tag="LLC22_000031"
     CDS             complement(35963..36472)
                     /locus_tag="LLC22_000031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433343.1"
                     /translation="MKKVTREEVASILVKDKYFSKGNYWLKIWQTLVALLGWMIVVLP
                     FIWVFFPLTRPERAKDFSLYAFLSEKKMLYFLIGFFVLIFFSFLITSFVLTRWNNRNL
                     YKKVNKSFEYEDEKLKKRQELLEEVYTERFGTKEERETVRFYSVSEEKNLDTTFIADL
                     YKENGVELK"
     gene            complement(36647..38782)
                     /locus_tag="LLC22_000032"
     CDS             complement(36647..38782)
                     /locus_tag="LLC22_000032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5433344.1"
                     /translation="MVNTQKQLEEAYLKNVYQKLIDKKNELRESMDTAKIEGNQSLKE
                     MAGELRLNFDSYLDNLDTFSMIEMKNREIDQMNIKQKNAENQLAKIERLLKSPYFGKV
                     VVDFLDNEPKESFYIGTANFTDDADENLVYDWRSPIAELFYNNMIGPSSYTVRQNKID
                     TVIKERRQFLLERDRLVKFFDTSVAIQDDVLLEVLGQDETNEMKAITATIQSEQNTII
                     RDVKSQNILVNGVAGSGKTSAIMQRIAYLLYLYRDTMTSDDLLILSPNHRFIDYISNV
                     LPSLGERNPLNLTIIQLVSQLSAEEIEGEEAYFKRITGENVSEQTERLRSKKFIDNLK
                     QSDPLFLDHPNFIRGLTKNGKTVLSKKTIEKIYEKVPAHPKLIDRLQATKKALMSEWK
                     NHLLKQAKSPAVQNQVLSLTEDRQLELFGKLISDDSEQSIVAYARKLLQKKYRKITRQ
                     IEEMAWVDEHQLFERIYEKRYGSAYAWQPTRTVDEAVIILAIRHLLVEKVNVPAFRYL
                     LIDEVQDYTLAQLGLLIELFPKTHFTLVGDENQAIFNSSTTFADIMRCFDDYHLPIHR
                     YDLRNSYRSSGAITELFKTYAVDQEKIDIVSIRPQGKEPEYRSFRSSEELLKILAEIL
                     VSLKGEKAAVITQTEEETQTLQESIKKNSYGLENCQIIPLSLAKGLEFDHVILYPFEN
                     DGDEQRRRRQMYTAISRGMKSIVVLERAT"
     gene            complement(38865..40520)
                     /locus_tag="LLC22_000033"
     CDS             complement(38865..40520)
                     /locus_tag="LLC22_000033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5433345.1"
                     /translation="MKIVIVGGVAGGMSAATRLRRLMEDAEIVVFEKEPYVSFANCGL
                     PYYLSGEISERENLLVQTPESLSARFCLDVRPNHEVTAIFPENKTVEVVHEGQKHIEQ
                     YDALVLSPGAKPVVPSIPGITEADNVFSIRNVPDIDKVMHALEKQPKRAVIVGAGFIG
                     LEMAENLKRRGLEVMVIEQAPHILPTLDEEMAAFIEKELSHQGVEVITSHAVAGFEDH
                     GKRLRLDDGRTIPADLVILSIGVRPDNQLAVTAGIELGIRGGILVDERYQTNIPDIYA
                     VGDAIVVKQQITGKDALISLASPANRQGRQVADTISGISRRNQGGIGTAIIRTFGMTA
                     ASTGLSERTAKENELSFEVIHVSGKDHASYYPEATDILLKLIFHPETGEIYGAQGVGA
                     KGVDKRIDILATAIKGHLTIFDLPELELTYAPPFGSAKDPVNMLGYAAMNIAEGLSET
                     VQWHELPTELAKGKILLDVRTAEELEKGKFKEAKHIPLNELRDRLNELDSQQEYIVSC
                     HSGLRSYLAERILKQSGYHVKNLDGAFSLYQTVRPEELIYPNK"
     gene            complement(40522..40836)
                     /locus_tag="LLC22_000034"
     CDS             complement(40522..40836)
                     /locus_tag="LLC22_000034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBK5433346.1"
                     /translation="MNLLFQSIKSITVPELKEKLLENPALLDVRTPAEYRGGHIKGAK
                     NVPLQSINRYDGDKEKTVYVICQSGMRSKQAAKELKKSGYDVVNVRGGMNQWFDRTVG
                     GK"
     gene            41006..41266
                     /locus_tag="LLC22_000035"
     CDS             41006..41266
                     /locus_tag="LLC22_000035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sensitive transcriptional regulator"
                     /protein_id="HBK5433347.1"
                     /translation="MEIDNKNILNRLKRTEGQIRGIQKMIEDEKECMDVITQLSAVRS
                     SIDRVMGMIVADNLKNCFEKPDSNPEEQAAKLEQAIKMIIKK"
     gene            41280..41594
                     /locus_tag="LLC22_000036"
     CDS             41280..41594
                     /locus_tag="LLC22_000036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsrE family protein"
                     /protein_id="HBK5433348.1"
                     /translation="MKVVFHIDELEKWSETGKNVKNLIKASPETTIVVSVNGIAITGY
                     LDSANAEFLDLQGVVFHACANAMRANHISESSLPEQVIVVPAGVLDLVELQSQGYAYI
                     KP"
     gene            complement(42324..42878)
                     /locus_tag="LLC22_000037"
     CDS             complement(42324..42878)
                     /locus_tag="LLC22_000037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-alcohol phosphatidyltransferase family
                     protein"
                     /protein_id="HBK5433349.1"
                     /translation="MKLSTDWRKEIQTIPNLLSIFRIFLLPIYLYFVLRQSFYIAGAV
                     IVVSGLSDYLDGVIARRYNQVTDLGKVLDPFADKLTQLFLILSMAWYRPWLWLLFGLF
                     LIKEGFMFVAGLIGLSKNIKLSGAKWYGKVATAVIYVGMILLLLFPELPTLWVRVIFA
                     VITYGLLQSFVLYAVEYRKMFQRK"
     gene            complement(43004..44933)
                     /locus_tag="LLC22_000038"
                     /pseudo
     CDS             complement(43004..44933)
                     /locus_tag="LLC22_000038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336853.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
     gene            complement(45239..45955)
                     /locus_tag="LLC22_000039"
     CDS             complement(45239..45955)
                     /locus_tag="LLC22_000039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBK5433350.1"
                     /translation="MNSDMTQIMGKFIGTLILVLLGDGVCAAVNLNKSKAQASGWIVI
                     AFGWGLAVTMAVYISGFMGPAHLNPAVSLAMAMKGAISWNLVVPFIIAQVLGAFAGAI
                     LVWLSYLPHWNATKDESAILGTFATGPAIRNYPANVITELIGTFVLVLGLLAFGQNEF
                     APGTNVFAVGGLILAIGLSLGGPTGYAINPARDFGPRLAHAVLPIANKGTSDWAYSWV
                     PIAGPMIGAIIAVGVYSLMV"
     gene            complement(45956..47779)
                     /gene="glpO"
                     /locus_tag="LLC22_000040"
     CDS             complement(45956..47779)
                     /gene="glpO"
                     /locus_tag="LLC22_000040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glycerol-3-phosphate oxidase"
                     /protein_id="HBK5433351.1"
                     /translation="MFSNKTRQDSIQKMQQEELDLLIIGGGITGAGVAVQSAASGIKT
                     GLIEMQDFAEGTSSRSTKLVHGGIRYLKTFDVEVVADTVGERAVVQSIAPHIPKPDPM
                     LLPIYEGEGATTFNMFSVKVAMDLYDKLANVTGTKYENYTLTPEEVLEREPFLKKEGL
                     KGAGVYLDFRNNDARLVIDNIKKAAEDGAYLVSKMKAVGFLYDGDQIVGVKARDLLTD
                     EVIEIKAKLVINTSGPWVDKVRNLNFTRPVSPKMRPTKGIHLVVDAKKLPVPQPTYFD
                     TGKQDGRMVFAIPRENKTYFGTTDTDYQGDFTDPKVTQEDVDYLLDVINHRYPEANIT
                     LNDIEASWAGLRPLLIGNSGSDYNGGDNGSISDKSFNKVVDTVSEYKENKVSRAEVED
                     VLNHLENSRDEKAPSTISRGSSLEREPDGLLTLSGGKITDYRKMAEGALRLIRQLLKE
                     EYGIETKEIDSKKYQISGGNFDPTKLEETVTELAKEGVAAGLEEEDATYIADFYGTNA
                     RRIFELAKEMAPYPGLSLAESARLRYGLEEEMVLAPGDYLIRRTNHLLFERDQLDEIK
                     QPVIDAIAGYFEWTEEEKAQQTKRLEALIAESDLRELKGEK"
     gene            complement(47793..49289)
                     /gene="glpK"
                     /locus_tag="LLC22_000041"
     CDS             complement(47793..49289)
                     /gene="glpK"
                     /locus_tag="LLC22_000041"
                     /EC_number="2.7.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol kinase GlpK"
                     /protein_id="HBK5433352.1"
                     /translation="MTESTYIMAIDQGTTSSRAIIFDKKGRHIGSSQKEFTQYFPQES
                     WVEHDANEIWNSVQSVIAGAFIESGIKPNQIAGIGITNQRETTVIWEKDTGRPIYHAV
                     VWQSRQSAGIADNLKNEGYQEFFHEKTGLVIDAYFSATKIRWILDHVEGAQERAEKGE
                     LMFGTIDSWLVWKLTDGQAHVTDYSNASRTMLFNIHQLDWDQEILDLLNIPRVMLPKV
                     TSNSEVYGYTQGYHFYGSEAPISGMAGDQQAALFGQMAFEPGMVKNTYGTGSFIVMNT
                     GEKPQLSKNNLLTTIGYGINGKVYYALEGSIFVAGSSIQWLRDGLQMLQKASDSEDAA
                     KRSTSEDEVYVVPAFVGLGAPYWDQAARGAMFGLTRGTTKEDIIKATLQSIAYQVRDI
                     IDTMQDDTGIKIPVLKVDGGAANNEYLMQFQTDILNVPIQRAENLETTALGAAFLAGL
                     AVGYWKDTDEIREFYEAGKLFEVQMEEERREKLYNGWKKAVKATQAFE"
     gene            complement(49425..50885)
                     /locus_tag="LLC22_000042"
     CDS             complement(49425..50885)
                     /locus_tag="LLC22_000042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433353.1"
                     /translation="MKIEALLERKEQLQILILRNLVLQGGTASINGLREHVQLSKASF
                     DQYLEDIELIGRMMEKKVEVQRNEYQALLVLDEDVSLEKILLFLLQESLKFKMLVYLL
                     EHQQVSIVRLATAFNISESSVFRKIKELNQLLEEFGLQIKNGQLYGEELQIRYFYYEL
                     FQYIPEDQRPLFLQNTPEKRPFILGLDRVLETTFTASAEAQIACWLGITKKRLLNEKS
                     TYATLKEKKLLYQSDRLYQAIDPIIVMHLSRTAAELNVYETMMFYSFFVSFSIVDEEI
                     FYQYDLTRSKKLPTAVLDTYIRETMLWHYRPRRLKIKEEKAVGYQISQINNEWFFFVG
                     KIEVYERDRLLEQQQKMLGHSLTQLLAKLQETAVQQLPRKRAEDSELSYLMIQYANVL
                     LMIDFYIAKPVVIGIDLESLPIYRIAFQQYLIRELRGIGGIEIGSYEEGKEYDLVITF
                     CQRNKKQCEYYLSEFASPYDIIRLKRRIETLKKEKN"
     gene            complement(50875..52170)
                     /locus_tag="LLC22_000043"
     CDS             complement(50875..52170)
                     /locus_tag="LLC22_000043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5433354.1"
                     /translation="MNIVIVGGSFAGIHAAIYLRQLMPTSEIYLIEKQSKLGWIPSGF
                     NLILKGKVTSEKQLSWITKEELTDRYRIHVYTEKTVIGLKEKKVVLAGGKKLDFDRLI
                     LATGSNQKFRNISAESTLIHPVKKIQNVTALQQKIMNAKKIAIIGAGQAGIEIAEGLA
                     SRKKQIHLYESRKSILFRYLDPEMTEPLVKEMKNQGLSLFLEEQVVSLTENETAIVET
                     EKRKENYDLVLLANHSRPDNQMWEEQLTLNDDGTIWVDDYLQTSQKDVYAIGDAIQVT
                     FRPTNEKMYVSLVNNAVRTARNVSKTISGSQTKDQGTYRPVGNQWFGYFLGSVGLTEE
                     ESIFYPQKIETGYVDYKLTAINQSKVKLKFLFDSEKKILGAQLQSKKEMFHLLDQLTI
                     AVEEGWTFEQLEEHELFFQPEYRVPDMVWSKVANTAYED"
     gene            complement(52502..53179)
                     /locus_tag="LLC22_000044"
     CDS             complement(52502..53179)
                     /locus_tag="LLC22_000044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase
                     domain-containing protein"
                     /protein_id="HBK5433355.1"
                     /translation="MKVLIVLTNVEKYEKIERPTGLWLSELTHFYDVLVKNGIDADFV
                     SPKGGYVPLEPQSVLNMDEIDWAYYEDEDFRNRALGNTLRPDDVDANDYAAVYYAGGH
                     GTMWDFPEAIDLGKVASQIYRNEGLVSAVCHGVVGLLPVTDESGKSILAGRTVTGFSN
                     EEEEANGTTNEVPFLAEDALKEKGANYQSGAAFSEVVQIDGRLLTGQNPQSAHQLGEA
                     VVEALKN"
     gene            complement(53209..54300)
                     /locus_tag="LLC22_000045"
     CDS             complement(53209..54300)
                     /locus_tag="LLC22_000045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH-dependent flavin oxidoreductase"
                     /protein_id="HBK5433356.1"
                     /translation="MSQFDQSITLPSGVQLKNRLMLSPMTTQLSFFNGVITEDEITYY
                     KQRSKGLGAVITGAANVQDIGKGWPGELSIAHDEMIPRLSELAKAIQGEGAKAIIQIF
                     HGGRMTSRATLSGEQPVSASAVAAKRPDAETPRAMSEEEIVETIQAFGKATRRAIESG
                     FDGIELHGANTYLIQQFFSPHSNRREDQWGGSLENRYRFIEELLTTVFSAVEQYAKKP
                     FIVGYRFSPEEYETPGIRFEDTIWLLERLRESKLDYLHVSLNMYDRIARSDKYNDKSI
                     LEVVHNTIQGKIPLVGVGGIRNREDVEQVLKYAELAAIGQQMIVDPDWAEKLLENRED
                     EFVTKPFEEAYKELYLPSPLYNFLKARYQ"
     gene            complement(54401..54835)
                     /locus_tag="LLC22_000046"
     CDS             complement(54401..54835)
                     /locus_tag="LLC22_000046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5433357.1"
                     /translation="MEKPIEKALDECLFFSVKKLDRMLNKLADEAFRRTGLAPTYGFI
                     LLILKEKDGIPQKDIAQMLYSAPSTIARFVEKLEYKGYVKTVSEGRLSLVYLTEQGRQ
                     FAKEVDGSWEELHQSYKAVLGNEASKELAQTMNDATDKLQKK"
     gene            complement(55419..56876)
                     /gene="ascB"
                     /locus_tag="LLC22_000047"
     CDS             complement(55419..56876)
                     /gene="ascB"
                     /locus_tag="LLC22_000047"
                     /EC_number="3.2.1.86"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001336277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK5433358.1"
                     /translation="MKKFPEGFLWGGATAANQCEGAWDVDEKGLSVSDVYTFDSDLPK
                     EKWTDQWHMMTHQQVKAAQDPNSKYYYPKRHGNDFYHHFKEDIRLFAEMGFKCYRMSI
                     AWTRIFPHGDEETPNEAGLFFYDQVFDECLKYGIEPVVSLSHYEMPLYLVTEYGGWPN
                     RKLIQFYVRFAETVFKRYKNKVKYWMTFNEINCVKHHPFVSVGVIEENHPHLEQAKYQ
                     GAHHQFIASALATKACHEIIKGSQVGCMISYQLLVPYSCDPDDIQKTIEQQRTSLFFS
                     DVQARGYYPAYTQRMFEEKGVNLKIEVGDEEILAAYPVDFVSFSYYMSSAVSAHPENW
                     EGVQGNLITGGIKNPYLPSSEWGWQIDPKGLRIALNQLYDRYQKPLFIAENGLGAIDK
                     VEEDGTVQDDYRIDYLKQHIEQMKEAIKDGVDLFGYTSWGCIDIVSASTSQMSKRYGY
                     IYVDQDDEGNGTKKRLKKKSFDWYRQVIQSNGEIL"
     gene            complement(56873..58768)
                     /locus_tag="LLC22_000048"
     CDS             complement(56873..58768)
                     /locus_tag="LLC22_000048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5433359.1"
                     /translation="MEKPFSKNYTYLVRRIATALINKGEVKMDYSQLAKDIVRFVGGE
                     ENVSNVYHCATRLRFTLKDNKKADKEKVEQLEGVITVVEAGGMFQVVVGNAVNEVYDV
                     LSKQMKLEDDASSGKRGTEKKGILNSFIDMIAAVFAPTLGVLAGSGLIKGVLALCTSL
                     NLLTTESGTYIILNAAADAFFYFLPIFLAYTAAKKFNTDRFIAMVIAAALVYPTIVSA
                     YSDSITLRFLGMPVILARYTSTVIPAILAVWVLSYIEPKIRKSLHESIRNLLTPFICI
                     IVMVPIILLVVGPIADYASQLIAAGYLAVYNFSPVLSGAVIGGFWQVLVIFGLHWGLV
                     PVMTNNLSFYGRDTLGPACMTAVAAQAGAVLGVFLKTKNKKVKSLSLSAFITALFGIT
                     EPAVYGVTLKYKRPFYIACICGAIFGGVAGAAGAGALAVATRSILSFPIYIGEGFVWL
                     VASYFLAMISSCMLTFLFGYKDEIEEESSKDIVLSTPAAGEIIDLSEVNDPTFASGSL
                     GEGFAIIPTDGKIYSSVNGEVSTVFPTKHAIGVVSEEGAEILIHIGIDTVNLNGKYFQ
                     SAVSDGKKVRKGDLLMEVDLQELIKEGYDPTTMVIVTNSSRFKNIITSHKKNNQTRKL
                     ASLGGSI"
     gene            complement(58826..60601)
                     /locus_tag="LLC22_000049"
     CDS             complement(58826..60601)
                     /locus_tag="LLC22_000049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5433360.1"
                     /translation="MFITKRRCKQMDLNKRQLQILVVLRNKNHWITSEELAEALGTNK
                     KTIQTEIKNMLAIYEKKIIIQSNKRSGYFLESIESETKQQIIQEVTKHKIYSSMDFRA
                     STIVTYLLFQKGYVSMQKIADIFFLSKTAVSLQIKTILRWIERNPKLELEVSSTKGLK
                     IIAEENSKRIFLSLVGTETVIQHARLPQQISTIFSNIMPTVQKTLKEVLISYNYIVSG
                     EDFIRFSRYLVLTILRREELLEKTNRYTLFIPMVETLTKKLSSELPYSFSNQEKQAIE
                     NRLLELNYLMINDEKNKEIEKNLRAFEQTIIRFLDLPVSLLFHETEFLLTHIKQMKTR
                     MDAGHNTMNHFVQKIISRYPLEIYLIRRFFPIHFQLRPNLAESAYFVLYLAEALNPFR
                     KQGEILIVSNQPISILNTLKKQIQQSMNMWIKECRIEPVYLFKNQSNKITEYDAILTT
                     EQELIFEWDDLIYLPSVLDEFESWEIYQILREKLTIVEEKKKTKLLDHYYKEENQIKI
                     HKKIDSIQQLISPSSDLVMLPLNAETLLCCLIKSQVETKITEYQLEIPLIHQQRKIKR
                     VFFVSFDYKRNDILVFFQAVSDLLG"
     gene            complement(60651..62147)
                     /locus_tag="LLC22_000050"
     CDS             complement(60651..62147)
                     /locus_tag="LLC22_000050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5433361.1"
                     /translation="MDQEIFPENFLWGGAVAANQCEGAWLEDGKLPNVTDTLIGIMNQ
                     HPSIQWNEEKKIWEIALDESLHYLSHEAIDFYHRFEEDIRLLKELGLKAFRTSISWAR
                     IFPRGDEQKPNEAGLVFYDRLINTLNRYDIEPVITLSHYETPLALVGEYGGWQNRKLI
                     DFFEFYAQTVFERYQGKVKYWMTFNEINNAFRMPYAAAGLVTFPARDKLEPIATLTKK
                     VIYQACHHMFLANARATQLLKKIDPNAKMGIMCSFSALATYAYDCDPENVFGSLQFKR
                     NSWFFSDVMCRGHYPAYIYRTWKEEDCAPVMLDGDEQCLQANTADYIAFSYYRSAVYK
                     KEAEMRVDTGGANGFDNPFLKEKSPEPWSWPIDPLGFRYVMNELTDRYELPLFIVENG
                     IGLDEAPDELNRIHDPKRCEYLKIHLQEIAEAIKDGCQIIGYLWWGPIDIVSAGTGEM
                     RKRYGFIYVDRQNDGSGSFRRLKKDSFEYYKQIIQSNGKNLEYRSFFK"
     gene            complement(62341..63963)
                     /locus_tag="LLC22_000051"
     CDS             complement(62341..63963)
                     /locus_tag="LLC22_000051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000415199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBK5433362.1"
                     /translation="MEQKWWHHSVVYQIYPRSFQDSNQDGIGDLRGIISRLDYLAYLG
                     IDAIWLSPVYESPNDDNGYDISNYQAIMAEFGTMEEMEELIEEAKKRNIRIIMDLVVN
                     HTSDEHPWFIEARKNKENPYRDYYIWRDPVNGKEPNRLRSIFSGSAWQLDEKTGQYFL
                     HLYSKRQPDLNWKNKQVRQEIYQMMNFWIDKGIGGFRMDVIDMIGKEPDKEITSNGPK
                     LHEYLQEMNQATFGDKNLMTVGETWGATTEIAKLYSNPKRNELSMVFQFEHIGLDQQE
                     GKDKWDLKPLSISELKKVLSKWQTSLGDEGWNSLFWNNHDLPRIVSRWGNDDVYRKES
                     AKMFAILLHMMKGTPYIYQGEELGMTNCPIDDIAEAKDIETINMYNERISSGFTKEEI
                     LESIKAKGRDNARTPMQWNAREHAGFTTGIPWLRVNPNYKEINAEEALADQDSVFYMY
                     KKLIDLRRKHDIIVWGDYELVEKTPEHVFAYSRIYEDQQWLVICNMSSEKQTFTIPRE
                     ALRVIVSNYPLKQLPDGKVDLRPYEAFVLEVK"
     gene            complement(64291..65604)
                     /locus_tag="LLC22_000052"
     CDS             complement(64291..65604)
                     /locus_tag="LLC22_000052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBK5433363.1"
                     /translation="MKEKILSYFEIEKLNTTVKREVLAGFTTFISMAYILFVNPTVLG
                     ASGMDEGAVFTATALASAIGCVLMGVLARYPIGTAPALGINAFFAYSVCLGMGIPWET
                     ALAGVFVASLIFILITIFKLREMIIDAIPADLKYAISGGIGLFIAFLGLSEGGIIVSN
                     ESTLVGLGSLNVGSTWLTIFGLVVTAILLVRRVPGGIFIGMAATTILGLVTGLIPMPS
                     EIVAAAPSLKPTFLVALKHVGDINSLQMWVVVLTFLLVTFFDTAGTLVGLANQAGFMK
                     DNKMPRVGKALASDSTAMLAGSLFGTSPVGAFVESSAGIAVGGRSGITAITTGIFFLL
                     GLFFSPLLSVVTSQVTAPALIMVGVLMAQSLRQIEWGNLEIAIPSFLILIGMPLTYSI
                     SDGIALGFIFYPITMLAAKRGKEVSPIMYGLFFVFVGFMWILNVK"
     gene            complement(65849..66073)
                     /locus_tag="LLC22_000053"
     CDS             complement(65849..66073)
                     /locus_tag="LLC22_000053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433364.1"
                     /translation="MDLMGRLEGYLKYRRAKHSEKLRAKNLKSGKKKTKGWGKMVDTG
                     FGGLNNLNPVDTKEFIKEEQKRNGKIKSHY"
     gene            complement(66093..66515)
                     /locus_tag="LLC22_000054"
     CDS             complement(66093..66515)
                     /locus_tag="LLC22_000054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glyoxalase"
                     /protein_id="HBK5433365.1"
                     /translation="MESVYRQERKSNRKKGQMMIQKTRVMLYVNDVEMICRFFVEKIG
                     AEISETIELPEEFKSIVLSISKELELGVFPKVFVQKFSPEVLGPPPSLVFFTDEFETI
                     YENMEEPGEITDNNGILTFNFSDPEGNYFVIGKAESSD"
     gene            complement(66658..67368)
                     /locus_tag="LLC22_000055"
     CDS             complement(66658..67368)
                     /locus_tag="LLC22_000055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433366.1"
                     /translation="MKKVIVDTNFWEVFPEATIEILSVNGIDNHVTKESEETYHQLLN
                     EAAKEARNYLTEETFSQNEVIAQWRQAFTTFKTKKGARSSIEALLKRANQEREFFPIN
                     PLVDIYNSISLSFGVPCGGEDIEKIAGNLHLGKAQGGESFLPLGADSDAPALPEEIIY
                     YDEQGAICRCLNWREAQRTMLTEETQAAVLVIESINAEQAARGAQAIEALKEKIDQTF
                     GVTSVRHTLTKDESEAEL"
     gene            complement(67386..67883)
                     /locus_tag="LLC22_000056"
     CDS             complement(67386..67883)
                     /locus_tag="LLC22_000056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5433367.1"
                     /translation="MTPSDVDLLQQISIETFTDTFGKDNSPEHLADYLTQAYALEKLT
                     EELKDKETDFFLVSIDQEPAGYLKLNTGTSQSEEMADHFLEIERIYVRKKFKHQGIGT
                     FLLDTAIEKAKEKQKTAIWLGVWEHNDVALAFYRKKGFIKYSEHVFYMGDDPQTDYLF
                     IKQLF"
     gene            complement(67920..68372)
                     /locus_tag="LLC22_000057"
     CDS             complement(67920..68372)
                     /locus_tag="LLC22_000057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300731.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5433368.1"
                     /translation="MAEILRDIGMIARALDSISNIEFKEVDLTRGQYLYLVRICENPG
                     IIQEKLAEMIKVDRTTTARAIKKLESNGMIERLEDKENKKIKKLYPTKKGAEIYPFII
                     RENNYSNAVALNGLSDEEAKQLEYLLNKVCKNVSEDWNFVKKGNKRIY"
     gene            complement(68507..69112)
                     /locus_tag="LLC22_000058"
     CDS             complement(68507..69112)
                     /locus_tag="LLC22_000058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326433.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK5433369.1"
                     /translation="MNKKLAQYKRLLALSQAGLYYGKDVFDKERFEEIRTISLELISE
                     IGKETFEEIKALTTIGEGHPTPKVDVRAYIKKDGKVLLIEDKRTKEWSLPGGFAEIGL
                     SPEENVRKEVYEETGLTVETTQLRAVFDTNKQKDIPQLFQYYKLVFACAIHGEEAKFI
                     ENNETSNMGFFSIEELPKLSEKRTTKKQLLILENKNQIYCD"
     gene            complement(69562..70182)
                     /locus_tag="LLC22_000059"
     CDS             complement(69562..70182)
                     /locus_tag="LLC22_000059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBK5433370.1"
                     /translation="MKKYFILLAGSPGTGKTYLMNKLRERFPDMYAITLDEIKEYYAE
                     SIGFNNLEERAEQERTKVYPFYYKALDLYMEAGKKVIVSEYPFSDKQKARLQELADRY
                     GYQVITIRLTADFEVLWQRRYKRDRESDRHLSYIMDHYHYGDVLEDRTKGTNHITKEA
                     FKKIIADRKYDKFQLGTLYEFDVTDYTQVDYTPLLDKLEKEINDNK"
     gene            complement(70184..71053)
                     /locus_tag="LLC22_000060"
     CDS             complement(70184..71053)
                     /locus_tag="LLC22_000060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II fructose-bisphosphate aldolase family
                     protein"
                     /protein_id="HBK5433371.1"
                     /translation="MYTTLKEVTKTAEELNFTVGAFNTHNLEMLPAMLGAAKEMGSPI
                     IIQTSVDTAKYIGMHVLVNVMTAIAEEEMVDAVLHLDHARDFDDIKEAIDSGYTSVMY
                     DGSHLPFKENILKTKAVVEYAHAHGVSVEGELGTIGGTEEGIHVAENDKVYTRPEDAV
                     KFVEATGVDALAIAIGTNHGQFKSKTEVNIPLLKEIDAVVDVPLVIHGGTGVKEEDYP
                     ELINNGIRKFNVGTELLVNWTKVAKETFSETEINKSLRHNVIPANEAVKEIVKHKIGL
                     FMNLESPINLGNK"
     gene            complement(71076..71483)
                     /locus_tag="LLC22_000061"
     CDS             complement(71076..71483)
                     /locus_tag="LLC22_000061"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK5433372.1"
                     /translation="MFGFFKKKEKEPKKVLAKEEKALSPEATEKIQSEITQLKQEIST
                     TQDKHKLAKLYEQVGLKFSELYVNDQAIQYLEKSLENKQTIGDGYKKLMSLYNQKRAD
                     AARAGDDQGIDYYMGKMDEMRQIAKQVTIKGNK"
     gene            complement(71502..72791)
                     /locus_tag="LLC22_000062"
     CDS             complement(71502..72791)
                     /locus_tag="LLC22_000062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5433373.1"
                     /translation="MGVINFIIENILTQASITIALIAMLGLLLQKKSAGQVISGTLKT
                     LLGFQVLSAGSSIIVGSLTYFGKIFTEGFHMQGIIPSIESINGQAMNDLGLGRDIALT
                     FLAIFVFNIILARFTKWKYIFLTGQAILWMATMTTVFGYFAGLRGIVLILVGDFIGAC
                     FAIAMPAVAQPIIRKITGSNDIALGHFCTIGYLFEAGVAKLFGEKGENKKSIEDIKLP
                     THFEFLQDTYLSVMVVMVPLYIITVLFAGEPFASELSGDQNYIMFAFLQAIQFVVGVY
                     VLLAGVRLLLGEIVPAFRGIAMKLVPDAIPALDCPVFFPYSPNAVILGFITTTIGTII
                     AMFTLPMFGLAMILPGMLTNFFAGGTAGIFGNAVGGRRGAIIGGIAHGFFITLLPALL
                     VTIFNSMGFINATATDVDTVAAALLYAWILSPVLKAF"
     gene            complement(72818..73120)
                     /locus_tag="LLC22_000063"
     CDS             complement(72818..73120)
                     /locus_tag="LLC22_000063"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5433374.1"
                     /translation="MNKLNILFVCGAGLGSSFAAQMSAEDVLNKLGVEAKLDHCDISS
                     AVSMKPDVIITAENFRSQFEKFAVDPKTAMIYLKNIVSKNEIEEKITPVLQDKGVI"
     gene            complement(73145..75238)
                     /locus_tag="LLC22_000064"
     CDS             complement(73145..75238)
                     /locus_tag="LLC22_000064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5433375.1"
                     /translation="MKTRTIEILHRIMTAQYPVKAKHLASEFNVSQRTIRQEVLEANI
                     WLSSKKLPEIRTIRNKGFLLKLEKEKQARLETEIKDVKDGFLNRRERIFDLVLAVAYS
                     RIPIHLNKKEEEFQISKSTLDEDMRRLRATLVSYGIEIVSYGKQGLVYKGSERSIRTM
                     IYDFINQNLGMTDFFMNQDAQLTPAQKIFLHYFPLVEIKKIQEIYSNKLLKQEDDIYK
                     KQILLFTLIWIQRIRKHEFISAINWKNTEIKDSSFSAFIDHMIEEFQLDNVPQVERNY
                     LRFTIETFNARDISNSIEWVQAQLLTIQLIQFVENETHVPFHLKEEALFENLYKHMAA
                     LIVRIKNHIQVMNPLKENIRTNYFPIYRAVTHFVPTIEEVIGGKILEDEIAFLVIHFS
                     TIASVIKRDLNYVYKSVVVCNHGMATGNLLAENLKEKFPQIEITAVLSSKEIELVDKL
                     DVNLVFSTFQLNYRNKPLLVVDPILTETNILVIEDFLKRNEELQRLEPNSHESTELFT
                     QIIDVMKESGGRVDRIIYGKLEKLFETNNLEINKREIQPMLKDILTDSNIMIKEKATT
                     WEESIELAARPLVKENIVEERYVEAMIRAVNDYGPYIVIGKHMALAHARPEDGVNKLG
                     VSVATIEQPIDFGNPEMDPVKIIFCLAAVDSYSHLNIMKELIELINNEEKLDRLIECT
                     NIEDFKQLLFSVVEK"
     gene            complement(75727..76491)
                     /locus_tag="LLC22_000065"
     CDS             complement(75727..76491)
                     /locus_tag="LLC22_000065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIM44-like domain-containing protein"
                     /protein_id="HBK5433376.1"
                     /translation="MKKINYLAIILLVGLCLFALPTQGFAVAGGHGGGTSSGRSSGRG
                     SFGGRSYGGSYFGSRSYGRDSYGYYGPGTGPSSYEQTGFLALAVLSVGGVSAFSIVKN
                     KRQKKRLKAEILSRMSGTAKEKKAQFLEIQKIFMKIQSAWEEETPEKARSCYTDKLFA
                     EHQKVLQKNKADGVRNHTKKITIQEVGNYRQIHENSFAIRIDFRCCDYSVDRKDGRLI
                     SGSKTQRQYFSQIWYFDFSEKEKRWQADFIQPIMLD"
     gene            complement(76602..77471)
                     /gene="mdcB"
                     /locus_tag="LLC22_000066"
     CDS             complement(76602..77471)
                     /gene="mdcB"
                     /locus_tag="LLC22_000066"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase MdcB"
                     /protein_id="HBK5433377.1"
                     /translation="MINDERKKAVTQQLAALVEEALIAEVTLSPKPGLVDALDAGAHS
                     DMDYALFLKSAKTLTPFFEEMAQIAWHHAIDQELRERIAEIGRKAEKAMLIATNGINT
                     HKGAIWAMGLLISVIAQKISMEQPFSLSKILDDVSKLAAFPDTKYRHKKTTHGHRVKQ
                     KYGVNGAYEEAILGYPHIRLAIQAAKELDNDSYVQKQMHMLLVLMSSLDDTCVLHRSD
                     QKTLVEMQKLAHAASQSALPNRPFTALLHFCQENQISPGGSADLLSASLFMLKIEELW
                     TADTYICPMLLND"
     gene            complement(77496..78572)
                     /locus_tag="LLC22_000067"
     CDS             complement(77496..78572)
                     /locus_tag="LLC22_000067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase"
                     /protein_id="HBK5433378.1"
                     /translation="MFENKKIKINVSDFQKVSAVTAVMMQTILSFALANSHSATNTAF
                     LGTFYVIVKYTAPMFIFAIVYNMVKTSQHLSYWEFLKEKFFELVVPYLLWTTAYLWLF
                     PAVQQQTPYTDTASFLLKYVTGDGAPHLWYTVMMLQIQLFMPFFVWLGYKVFANKKYV
                     WPVLIGSTILYVAWYLFYQTQVLTGPYHDSWYLLDRFVASFMIYGVAAFVYHEKVYQY
                     LDRVRYLFLPVALVIAFFSVRSLLAHPGDLSFANAPYLNTIQSLYSLVIIFAVFIGAS
                     KMIVNDSPKLPLFKWLSVYAYRTYLANVFVFQVLLLLFKDSWLQLPSGVMILVAYLMT
                     ASCAFALSWLLHIIWVAIKKGFSK"
     gene            complement(78596..79189)
                     /locus_tag="LLC22_000068"
     CDS             complement(78596..79189)
                     /locus_tag="LLC22_000068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase holo-ACP synthase"
                     /protein_id="HBK5433379.1"
                     /translation="MIQAHDIVLFDKHEIEGFTLPEWVVLTEKMFGTVRRASTDHAEI
                     LPIGLRGPARNQRWSTEISKHAVKQVIHPWDIIEQESYRQEKIMDYPVYQQFHAARNI
                     LSGCKWGIGGSLGFELSTGIPAVKETSDFDLLLYANSPIELPIQVIQSHPAFFEQFDT
                     QVVTRQGGFSLKEYLREPEKKILLKTVEGPKLTKELW"
     gene            complement(79193..80869)
                     /gene="mdcD"
                     /locus_tag="LLC22_000069"
     CDS             complement(79193..80869)
                     /gene="mdcD"
                     /locus_tag="LLC22_000069"
                     /EC_number="4.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin-independent malonate decarboxylase
                     subunit beta"
                     /protein_id="HBK5433380.1"
                     /translation="MKNSFVELNARERVNALLDNGRELIDPFDQIIAPSLPAQGIVPE
                     SDDGIVVSRGTINGKQAVVIAMEGKFQGGGIGEVSGAKIVAALEHVLEENKKGNEIFP
                     VIVLDTGGVRLQEANYGLLSISEIGNVIIALKQYVPVIGLIPGRVGSFGGMSITSALM
                     SYLIATKKARVGLNGPEVIEQEAGVREFDSSDKDLIWNTLGSRQRVESKIIDELVTDS
                     VEAIKAAVIAAMDERKDTHRSESSAFYLSLLDSLDLSKPMAIDDYNEAIANHQAKSID
                     LPEVAEGNEPAAASVGYDWFAALTGMKNPTSSISTVYYGKSSKFIEEAIVTSIVPDPK
                     NPMYRVRNGEVGLVEGFRMGQILDHVYEEDKDKKVKRPIIVVIDVPSQAYGYNEELIG
                     IHVALANSAAAYAKLRQAGHPVIGLIAGNAISGAFLAHGLQSSRLIALNNKEITVQAM
                     SKESAARVTKRSVAEIEAAAEKVPAIAYDINNYTKLGAIYHFLEDITDQAASEQNVSK
                     VIEAINEAIQDVRNTNDTMLTNRYTNETAKTFGRVETNKVRAKMDEEWDA"
     gene            complement(80859..81158)
                     /locus_tag="LLC22_000070"
     CDS             complement(80859..81158)
                     /locus_tag="LLC22_000070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit delta"
                     /protein_id="HBK5433381.1"
                     /translation="MEQLAYKYPTKQPINKKIHVGVVGSGDLEILMFPTEKTESTVKI
                     CTGSDGFGEVWNNVLTRFFDRYPISADIVINDFGATPGVVYLRLTQAMEELSDEK"
     gene            complement(81260..82906)
                     /gene="mdcA"
                     /locus_tag="LLC22_000071"
     CDS             complement(81260..82906)
                     /gene="mdcA"
                     /locus_tag="LLC22_000071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010748322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="malonate decarboxylase subunit alpha"
                     /protein_id="HBK5433382.1"
                     /translation="MEKPNRNWASKREKKAQRLEKISNLLNGKYVETEKIVEVMEKLI
                     APGDKVVLEGDNQKQASFLSESLEKVDAEKVNDLHLIMSSISRPEHLNIFEKGIASKI
                     DFSYAGAQSLRVAQMIEDGTMKLGDIHTYLELYGRLFIDLIPNVVLVAADKADKDGNL
                     YTGFNTEETPTIIEAAAFKDGIVIVQVNEVVDSLPRVDIPGDWVDVVVKADKPYQLEA
                     LFTRDPQNITELQILMAMMAIKGIYAEHGVQSLNHGIGFNTAAIELLLPTYGESLGLK
                     GKIAKNWVLNPHPTMIPAIESGWVESIHSFGGEVGMEKYIAARPDVFFVGKDGTMRSN
                     RTLSQAAGQYAIDMFIGSTLQLDYEGNSSTVTKGRLSGFGGAPNMGHNPGGRRHSTPA
                     WQSLRDNDDPLGKGQKLVVQMVETYGSNKKPVFVEELDALAVQKQAGLANAPVMIYSE
                     DTTHIVTEEGIAYLYKAKTKEERQAAIAAIGGVTPLGMTSTKESLDSLRAAGIVKLPE
                     DLGIKRSEAKRSLLAAQTIDDLIEWSDGLYEPPMKFRTWS"
     gene            complement(82913..83824)
                     /locus_tag="LLC22_000072"
     CDS             complement(82913..83824)
                     /locus_tag="LLC22_000072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBK5433383.1"
                     /translation="MSTGFLFPGQGSQKLGMLADIPEMYMERLENVTGYRLVDKEENY
                     QDTVFIQLALLTKAVFYLDEMEKNGIQPDIAAGHSIGAFCAAVACRSLRFENAAELVY
                     HRAVLMKEAYPSGYAMGVVVGVTRSEAEEIVAKTFDPDHPVYLSNENCPMQHTLSGSI
                     EGLSVTLAEAKRHQAQTAKLLKVPVPSHCLLMNDTVKKFKPYMQSVHLSDARCLYIKN
                     TDGRATQDAEEIRKDLLENLAFPVQWNQMMDLAKELGMDLTIEFPPGNTLTKLIHTKF
                     GVDKGIRTINLDQHGIDDATFLYQKWR"
     gene            83944..84801
                     /locus_tag="LLC22_000073"
     CDS             83944..84801
                     /locus_tag="LLC22_000073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5433384.1"
                     /translation="MKLLHLQYFKKVFETKNVTQAAKELFISQPALSRAIKHLENELG
                     VPLFYHSGRNIETTVYAEEFYPYAVKTLDTLEEGIKLLSSVNEKIVTSVILYLEVASV
                     SIPNLVRIFMEKHPDIQLTIMQHHLPDDITDPVLYITSEMKPGMTNIPIMKEPVYVAI
                     PKKHPLAKKEHLQLEDIQRTPILMLSKSNAFRHTLDAALEAKSIELTISSTTDDPATL
                     RSIVKQGLAVSFFPKVSWSYDKNDPFVLREIKDLPLTRTIYLSSSFTEDHPLIKMIAK
                     TMREFYLGK"
     gene            complement(84988..85350)
                     /locus_tag="LLC22_000074"
     CDS             complement(84988..85350)
                     /locus_tag="LLC22_000074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MmcQ/YjbR family DNA-binding protein"
                     /protein_id="HBK5433385.1"
                     /translation="MLTKKELIDHINETYNLSPEYIFKKFPDYCVFRHQKSKKWFGVL
                     MSVPEEKIYDDASDHRIINILDLKVDPELGGILRGKEGYFPAYHMNKEHWISIDLRKI
                     EKLDELADLIDGSFKSTQ"
     gene            85696..87135
                     /locus_tag="LLC22_000075"
     CDS             85696..87135
                     /locus_tag="LLC22_000075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433386.1"
                     /translation="MYSLMKKIITEKDIRRHVSLVEQLLNHTKITVNELAEIIGTTER
                     TIFSDLQSIRSQLPEGWDIISDQAGISLQNQQNLLTNDLWEIFFKQSVSVELLKNLLF
                     TKKVAVPDFLADHGLSYGTLKRHVTKINQRLASYDLQIDLTKYTACILGKERAIRTFY
                     HRLLIPFTHNNYFFEDYSIHESHYFQFLRNLSQTELAVETEEIFGTCWFFINTIRIKA
                     NCRLDSSIHTNSTLSSLYDSALKKLYLTEGIYLKDTELSFASFCFLESWNYNNNYGQE
                     TARCLHHSPFLEVLETFVEELASELSLDQLKKTSLTDNLALLILKYHESPILIEALDR
                     QYHRFLETYDQQYAHLYQQKENLLNDLKKEIEINEPNYFLQLLSLLIQQTIFSIKPNL
                     FNVYFIFQGEPSWKAFLQQELKDYLGKRVCFLPIELTDLSTISFEKTDILISNFPLDS
                     LDIPIVYISSIPTKNELNRLTELTFKTFL"
     gene            complement(87142..89694)
                     /locus_tag="LLC22_000076"
     CDS             complement(87142..89694)
                     /locus_tag="LLC22_000076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IC family P-type ATPase"
                     /protein_id="HBK5433387.1"
                     /translation="MNWYRLTVEDVLKNYQTSTEGLSQEERQKRLTDQGYNEIKARQQ
                     TKRWKKIAKHFTDLLMIVLIIASFLKFASSEYIEGSIILFVVIVNGLVSYWQERKAEE
                     SLNGLKQLMGQEAIVLSNGMQEKIPAKELVKGDVIVLRAGDVVPADIRLIEAHDLLVE
                     ESILTGESEASEKSHAVLTEEESIGDQKNMGFSGTLVQSGSAVGVVVETGNTTEIGKI
                     NQALQSVEQQTTPLIKKINRLNKQIFQGILCLSLFLVIFTTFRYGMDWHILLSATIAL
                     VVSMVPEGLPAVLTMILSVGVHEMAKEKAIIKGLPSVETLGSMTVICSDKTGTLTKNE
                     MTVVDVAAKEEACVLSIMKNCQELKTKEEQKTENLSGNPTEVALIRHTETANLPLKKI
                     EAKIPFSSEYKYMATMHAEEKGAVIYVKGAPEVLFAKSTLSSAEQEAWSQTAAEFARK
                     GQRVLGFAYKKVDSKQELTHETLTQLTFAGIAGLIDPPKESAVKAVKECQQAGISVKM
                     ITGDHKDTAKAIAEQIGLKHTAKVLEGIDLDLMSDEELIQQVPIVDVFARTTPEHKLR
                     IVKALQKNGEIVGMTGDGVNDAPALKRSDVGIAMGIKGSEVSKQAADMVLGDDNFHTI
                     AKAVKEGRRILDNLQKTINFFLPTALAQGLILIWALMLNRPLPLSPVQILWVNMVTTI
                     TLSYALGFESPDPEIMKRPPRDPKQGILSGYHLFRIIYVSLLIMVPAYLLAMQFEGQS
                     LQQTILLQNIVLAQAVYMINCRELSKPSLNQGLLQNKALFLSLGILALLQGMVIFLPV
                     GQQLIGTVSLTMTQQLLIGANVILLFLVVEIEKGIMNKLFRKKEKTAREYSR"
     gene            complement(89808..91139)
                     /locus_tag="LLC22_000077"
     CDS             complement(89808..91139)
                     /locus_tag="LLC22_000077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5433388.1"
                     /translation="MEKPAMKRTLTNRNIQLIALGGAIGTGLFLGSAKAIASAGPAVI
                     LVYLICGLAIYGLMRAMGDLFLANSTFNSISDFVDYYLGKKWAFFVNWTYWLCWLGAG
                     LAELTAIGLYIHFWFVHVPALISGGSALMILMAVNLVAVKWFGELESFFSIIKILGIF
                     LFILLGIGLSVSDFHTQSIGIKENFGQIDELLPFGFAGMVVSFPMVLFSFAGIEMIGL
                     TVGETSDPQKNLKKAINCLPWRILFFYIGTILSILFVVPWHCLDLKESPLVTMLQVIH
                     CQGGAAIVNLMILVASLSSANSAVYSTSRILYQTAKEKSLPHWFCALSKKGVPLHGIL
                     ITGMLFFAGLCLHFFVADSRLFFQLLAGMTTSCFLFVWSSILCAHVQFIKEKKRNTTQ
                     RYKDLALLVFFTSIAFSLLFESTTRFIPFLLVIWFVFLNFVYKRISNRNIS"
     gene            complement(91105..92583)
                     /locus_tag="LLC22_000078"
     CDS             complement(91105..92583)
                     /locus_tag="LLC22_000078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5433389.1"
                     /translation="MKDTGSSKQITTMTFIGMTCALVASVRNIPDVAATSWTMIFYML
                     VAVLLYAFPISLISGEFAGMFPQKGGPELWVSNALGKKWGFVVSWLLWVQMFPGMVMV
                     ASALAPLFGNIIDNVPLGLNSKFTLVVILVVYWIITFLNLKFDMAKIGGKVGVWLGLY
                     VPLTMMLLLGFAAWIKVGIVPTGTLGSFSWDKLIPDTTTASSFVYFAPIMFIFTGIEM
                     SSVYITRLENPVKTYIRGVFAALIFIFFVNILNALVVANVVPKGQMELNNIAQSISIY
                     CQILGLPHLIVNLFSLLVFIGVAVQLSAWASGPAKTVTESARKGAYPPKFNFWKTNQF
                     DVSKSVILTQSVIISIFALFYLLIPGVNQAFLMLVNSTTVIYCIVYVIMGIAVLRLRY
                     THAKLNRPFRIGKKEKKSNLGVWTVVIVLFAAIGFSVGLTMKAGTWINLIAVTAISVI
                     LFVVPLCIEKIKKPSWEQEVAMLLEKEKGELDGKTGNETDSN"
     gene            complement(92888..94723)
                     /gene="tdc"
                     /locus_tag="LLC22_000079"
     CDS             complement(92888..94723)
                     /gene="tdc"
                     /locus_tag="LLC22_000079"
                     /EC_number="4.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine decarboxylase"
                     /protein_id="HBK5433390.1"
                     /translation="MKDMDIKAVFIGDKAENGPVYKMLLNKMVDEHLGWRENYIPSDM
                     PAISEGDKLTPDYLATRDHMIEVLDEVSQRLRAGSIPWHSAGRYWGQMNAETLMPALL
                     AYNYAMLWNPNNVALESSMATSQMEAEVGQDFASLFNMTDGWGHIAADGSIANLEGLW
                     YARCIKSIPLAVKEVLPEKVKKMSEWELLNLSVEEILEMTESFTDEEMDEVKAASSRS
                     GKNIQRLGKWLVPQTKHYSWMKALDICGVGLDQMVAIPVQEDYRMDINALEKTIRELA
                     GQKIPILGVVAVVGTTEEGQVDSVDKIVQLRERLKDEGIYFYLHVDAAYGGYARSLFL
                     NEAGEFVPYASLAEFFEEHHVFHHCVTIDKEVYEGFRAISEADSVTIDPHKMGYVPYA
                     AGGIVIKHKNMRNIISYFAPYVFEKSVKAPDMLGAYILEGSKAGATAAAVWTAHRVLP
                     LNVTGYGQLIGASIEAAQRFREFLDHLTFTVKGKTIEVYPLNHPDFNMVNWVFKEQGC
                     TDLNAINELNEKMFDRSSYMDGDVYGERFITSHTTFTQEDYGDSPIRFVERMGLTKEE
                     WKKEQKITLLRAAIMTPYLNDDRIFNFYTKKIAKAMEKKLNEIIQ"
     gene            95193..96620
                     /locus_tag="LLC22_000080"
     CDS             95193..96620
                     /locus_tag="LLC22_000080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433391.1"
                     /translation="MIEEYIEKNILRQLFLCGQFYVNKEVNLEKLSNLLHVCKTTLLN
                     DINNIKKEFEEQIAYTHREKDRYTLYFSEHIPRCKIMQQLSQNSLFLKTCLLYLEEDE
                     PDYLQLTECEFISVSKAYSLKKQVLAYFNDCGIEIDRYSPRFTEMERRLLLLNVSYRL
                     GGFNSWELPESFFERADRFIESVTENSGRFYDKENKEILSIGFAISFLRQQVCAVTID
                     SKFIEEIKKRPIYNYVESAWENTDFQTYYKKEEFAFILTLFNLCNYGFHSYQLIAEDF
                     QQLHQVFIDNTPEIKELVATFESHFNQELFGNQPFERALIHLMRSAWDNYQLFMPEKF
                     YLLNEEQTNLYKEVQTIFSSWSSQLPYDLRLNPNCMRAFVIELSGILRLTKEHLTIYI
                     VTNSDVHYLIYREALEAVTTFDFQVAPTIYSSISDIKKYAQQSSNRVLCERTLYTPDA
                     VQYENIIPISINTIDRAIISAVQNK"
     gene            complement(96712..97077)
                     /locus_tag="LLC22_000081"
     CDS             complement(96712..97077)
                     /locus_tag="LLC22_000081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBK5433392.1"
                     /translation="MTTELMQFLLPYFEKLVLGLDIFAICLLVWGVCLSIKDFLKYLF
                     VHTKVQSDRVSENNAIKKMLGGYILLSLEILVSAGIIESIIKPTLQDIFQLAALVVIR
                     TIISYFLNKEIGPVDVQNK"
     gene            complement(97074..97439)
                     /locus_tag="LLC22_000082"
     CDS             complement(97074..97439)
                     /locus_tag="LLC22_000082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1622 domain-containing protein"
                     /protein_id="HBK5433393.1"
                     /translation="MFRSNLIEFLEWIIAILNICSIGILIVGIVLVLFKLFDWSHVKK
                     NYAERNTRNADTRKLLASYILLSLEVLVVADIIESVIKPTWTDILKLALIIIIRTVIS
                     YFLNQEIEDKEKQRRGEVG"
     gene            complement(97631..97879)
                     /locus_tag="LLC22_000083"
     CDS             complement(97631..97879)
                     /locus_tag="LLC22_000083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433394.1"
                     /translation="MKNASLFSLSISKDSSFLLECQMIGREEKGNFDKKEEVSDFPVN
                     KNRVGKKKRFEEVYGSIFRNLGTKKAPRQCFFEKLMTD"
     gene            97878..98006
                     /locus_tag="LLC22_000084"
     CDS             97878..98006
                     /locus_tag="LLC22_000084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methanol dehydrogenase"
                     /protein_id="HBK5433395.1"
                     /translation="MSKKLIKVGIGLGLLALGAAYLGKKTGLFEDDSHLYDEFESI"
     gene            98063..99757
                     /locus_tag="LLC22_000085"
     CDS             98063..99757
                     /locus_tag="LLC22_000085"
                     /EC_number="4.2.1.53"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oleate hydratase"
                     /protein_id="HBK5433396.1"
                     /translation="MRKSKAIMIGAGIANMAAAVYLIQEGKWKGDQITFYSLDDHGSN
                     DGAPTDTVVDEYWNKNHPLENQKGYIARGGRMLNYRTYVDLMDLLSRIPSVTEPGMTA
                     EEDTRDFDAKHRTFDKARLMEGGKGIIDGGKLGFNNKDRILLTKLIAMPDSEEEKLDN
                     ITIEEYFKDDPHFFETNFWFMWETTFAFRTRSSAQELRRYMHQMIYEFTQIEHLVGVN
                     RTRYNQYESIMLPLIEYLKEQGCKIILNRRVTDWEFKETPMQDEITVTGLKITNTLTQ
                     EEEYVVVDEDTAVIFTNGSITDSATLGDYETPAVENMDYGAASSLWKKASERFYNLGN
                     PDKFFADRDASEWVSFTLTTKNHLLLNEITRITTQEPGNALNSFISTTPITPLGQKDV
                     NMSIVVHHQPHFTSQKPNETVIWGYFLYPRRRGEFVDKQYIKMNGKEMLEELIGQLSK
                     VDPGPVNIREKETEIFDSVINNIPVYMPYASALFNNRAKSDRPKVIPKHSTNLAFTGE
                     FVEQPYQMIFTEQSAVRSGEIAAFHFAGIPMSRLVKTPRYDKDIPTLARAAKKMFE"
     gene            99857..100030
                     /locus_tag="LLC22_000086"
     CDS             99857..100030
                     /locus_tag="LLC22_000086"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433397.1"
                     /translation="MQAFEHHLPRGYEKAALHQVIRAAKLKQLLMFLTWLDLLPQMQA
                     FEHRLPRGYEKGV"
     gene            100408..101541
                     /locus_tag="LLC22_000087"
     CDS             100408..101541
                     /locus_tag="LLC22_000087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase catalytic
                     domain-containing protein"
                     /protein_id="HBK5433398.1"
                     /translation="MKAVTWQGKQKMEIRNVDDPKILEPTDAIIRITATAICGSDLHL
                     YHHGEAVLEKGYVVGHEPMGIVEEVGSQVQTLKKGQRVVIPFNISCGHCHFCLNHMES
                     QCDESNPDQLYGGLFGFGKLNGNHWGGQAEYLRVPYADSTSFVVPDNDLPDEKVLFLS
                     DILPTAYWSVENAGVKKGDTVVILGSGPVGLFAQKFAVMAGAERVIAVDPVQHRLDKA
                     ANYNGVETYFLEDTAQAGTELYELAKGGADVIIDCVGMDGLEPVKEKAKNLVSLQSGT
                     ISPLQMASQAVKKFGTVQVTGVYMTPASSYPLQEFFMRDIAVKHGQAPIIHLMPKIYA
                     MIAEGLFDPTQIITHSLPLSEAAQAYEIFDKKEDKNIKVVLKP"
     gene            101572..101892
                     /locus_tag="LLC22_000088"
     CDS             101572..101892
                     /locus_tag="LLC22_000088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YrhK family protein"
                     /protein_id="HBK5433399.1"
                     /translation="MPKIKRNTHEIEIGKEEDIEIRGRRFRFYFQNRYTLISLAVDLL
                     TGIFYIFGSLASLTKIPDRYGTYFYLAGAIFLTIRPILRIVRNIFIYDEKKAMKRTSK
                     KKEA"
     gene            complement(101921..102385)
                     /locus_tag="LLC22_000089"
     CDS             complement(101921..102385)
                     /locus_tag="LLC22_000089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5433400.1"
                     /translation="MVTYNWIKLREHPELVKQSANWFSSKWGVPAVVYEESIRTGIAN
                     KESIPQWYVVLDEKETIVGGAGVIENDFHNRPDLTPNLCALFVEPEKRKQGIAKRILA
                     EIRKEMHQLGYEKLYLITDHTTFYERYEWTFLTMVKEESGTTARLYQSDTIG"
     gene            complement(102517..103771)
                     /locus_tag="LLC22_000090"
                     /pseudo
     CDS             complement(102517..103771)
                     /locus_tag="LLC22_000090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628205.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
     gene            complement(103800..104117)
                     /locus_tag="LLC22_000091"
     CDS             complement(103800..104117)
                     /locus_tag="LLC22_000091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK5433401.1"
                     /translation="MEDQKNLEAIMGLIMFGGNAKSDAMEAIAAAKKGDFTLADEKIK
                     DAEESLVQAHHSQTEMLTQEAQGNHVEVTLLTVHSQDHLMTSIAFTDLAKEIIDLYRR
                     LNA"
     gene            complement(104143..104463)
                     /locus_tag="LLC22_000092"
     CDS             complement(104143..104463)
                     /locus_tag="LLC22_000092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5433402.1"
                     /translation="MEKKTIMLVCSAGMSTSLLVTKMQKAAEAKGMEADIFAVSASDA
                     DNQLESKNVDVLLLGPQVRFMQNQFAEKLAPKGIPLDVINMADYGMMNGEKVLDQAEK
                     LINK"
     gene            complement(104927..106342)
                     /locus_tag="LLC22_000093"
     CDS             complement(104927..106342)
                     /locus_tag="LLC22_000093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5433403.1"
                     /translation="MKITIPKNFILGAASSAWQTEGWKGKKEGQDSFIDSWYKNEHFV
                     WHNGYGPAVATNFMEQYQQDVDLMKSIHLTHYRTSINWARFFTDYENCIVDEEYAQHI
                     SEMIDSLIEADVEPMICLEHYEVPAFLLEKYDGWSSRKVVDFYAKYAQIAFDRYGDRV
                     KNWFTFNEPIVPQTRCYLDAVRWPHEQNTKKWMMWNYHKVLATAKAVEIYRSGNYGGR
                     IGCILNPEMVYARSNSPEDQKAAYMYDLFYNRVFFDPMVKGYYTEEFLELCQKQSIYF
                     DPATEDLETIQHHTVDFLGINQYYPKRVRAPRYQWNEETPFHPERYYEVFDLPGKKMN
                     NSRGWEIYPKIMYDIAMYLKENYHNIPWLITENGMGREYEEQYMDEKGIVQDDYRIEF
                     IGQHLHYLIKATEEGANCEGYMLWAFTDCVSPMNAFKNRYGLVRIELNDERSRTLKKS
                     ASWYQTLIDKRELDLPDEIYK"
     gene            complement(106359..107675)
                     /locus_tag="LLC22_000094"
     CDS             complement(106359..107675)
                     /locus_tag="LLC22_000094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5433404.1"
                     /translation="MRGSGMSFMDKLANVLGNVATRINNLRYIMVIKNAFAALIPVII
                     TGAFGTLFSAMVFDSENGLAQISFLRFLEELKPIASAISYVTLSFLTIYAVFLIGIEL
                     AKLNKVDGVFPGIIAVMSYLSVNPTVYELVNENQTVIVENVLAKQYTDTKGLFLGMLV
                     SILSIELYCWLRKQKKLQLRMPDTVPTNVSASFSALFPTILTVSGIAAAGFIIKELTG
                     MYLYDIIYNVVQRPLEGVVQGLPGILLLMFIAQVFWVIGIHGNQMVKPIREPLLLAAI
                     AVNTEAFEAGKEVPNIITMPFWDMYMSMGGSGVTIGLLIAVLLVGKREDMKQITKLSL
                     APGIFNINEPVIFGMPIMLNPILAIPFILTPLITGTIGYFATALGFAAKAVVMVPWPM
                     PPIVNAYLATAGNIGAVITQLVCIIVSILIYLPFVKVANRVENDGI"
     gene            complement(107825..108523)
                     /locus_tag="LLC22_000095"
     CDS             complement(107825..108523)
                     /locus_tag="LLC22_000095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FadR family transcriptional regulator"
                     /protein_id="HBK5433405.1"
                     /translation="MEENKTLVEVTTDKILRYLKEMQLQVGDKLPNEYELSDYLEVGR
                     STVREAVRALASRNILEVRQGAGTFVSDKRGIANDPLGFSLIEDQDRMIRDLFELRYL
                     LEPKMAGLAAEYATKNQIVQMKKLTQKIETSFREGTQEHVQLDIDFHTMIAEASGNVA
                     LLHIIPIINESIALFNKNYDIQHLKIETIDIHTEIVQAIERRNALAAFDAMTVHMAIN
                     RRELQKIIGEKETN"
     gene            complement(108812..109768)
                     /locus_tag="LLC22_000096"
     CDS             complement(108812..109768)
                     /locus_tag="LLC22_000096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5433406.1"
                     /translation="MEYRKSGHSGLKLPILSLGLWQNFGDYDPIHNQREILRGAFDMG
                     ITHFDLANNYGGPAGAAEKNFGRIFREDFQAYRDELIISSKAGYHMWEGPYGEWGSRK
                     SIISSCDQSLQRMGLDYVDIFYHHRPDPDTPLEETAEALMQLVRQGKALYIGISNYNG
                     EDTKKMTEILKRKEAPFIIHQMRYNMFSRALLEDDLSPVLEEEGLGAITFSPLAQGLL
                     TNRYLHGIPEDSRAHRKEIPFLSEEQVGSTLEKIKALQTIAVSRGQSLAQMALAWNLR
                     QKSVTSVLVGASRLSQLQESVRMMDNLDFSPEEELRIDQILE"
     gene            complement(109881..110714)
                     /gene="msrA"
                     /locus_tag="LLC22_000097"
     CDS             complement(109881..110714)
                     /gene="msrA"
                     /locus_tag="LLC22_000097"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5433407.1"
                     /translation="MDEEQIFIQTLYNLILNPNTRDWERKVLIQTKNDIRENISVKEQ
                     LSKLEATLRPLAIRMNLTPDVMDFYLLITEGFDKEQKYDFSKHAMQDADYQERAVFAG
                     GCFWCMVEPFESKKGILSVLSGYTGGHVEKPNYDQVSGGYTGHVEAVEIIYDTREISY
                     SELLTIYWQITDPTDTFGQFQDRGKQYRPVIFYQGERQKELAEQSKQKLDSSGTFHQP
                     IVTKIEPAGTFWPAENYHQQFYKKQPKRYKKIQQARNQFLIYQRVKNKWQKNIRKNHF
                     D"
     gene            complement(110889..112517)
                     /locus_tag="LLC22_000098"
     CDS             complement(110889..112517)
                     /locus_tag="LLC22_000098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433408.1"
                     /translation="MKINKKVVILSGLIIVSSIYSFIFFKNTQSIYTTGDLSFHLSRI
                     KGLSTIFTSPINYETFNYTGYGVNYFYPFLTFFPAVMLYWMTKNLIVSYIIYVWLLNL
                     CTTLVAYHYGERFLKQKKAAFLFSCLYIFSAYRTVDIYYRSAIAEAIAITLVIPVLFY
                     AYQIISGKEEKYPSVKLALSMSLLVYSHVLSTLMSTALIIIFIRLVSKGFKNADFIAI
                     FKKLFSAAGMTLVLTSAFWYPMFEQMLYQKINKPSVTNLYAHASNVFDSLTEAMNNDL
                     TTYSMGLVGLLSLCIPLILFKKLTNIEKKIYYGTCLTWLATTSLVPWYLLQNTPAKLL
                     QFPWRILSLQIIFSSLILTMIFFKNRRYNKTRELFYLFMTVLLLITLTVSSKKNFNQK
                     IISQPGHIVVNKETVEAYTTKGMDYFLYDYSPIASLENKEHIIKHEAKIGSQWVNLPY
                     KTTGSSIIYRVTNEKSQVITLPVYAYLGTNVEINHQPVKEQVNANGLVQISGVKGVAD
                     IKVSTSYTVTTIISYLVTLTAYLCLFFKIVFHKR"
     gene            complement(112504..113838)
                     /locus_tag="LLC22_000099"
     CDS             complement(112504..113838)
                     /locus_tag="LLC22_000099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433409.1"
                     /translation="MDAAFLFSCLYTFATYRTVDIYYRSAIAEAIALTIIPAVLYYAY
                     GLIFNREKKVIALSVSISLLVYTHVLTTLLCSALIACMIIVRLFLSKQIKNDIKFVVV
                     NLVKAVFLTCALTSYFWYPMLQQMNYQEIHSPFKTDLQLEALSISDSIIQALNNDITT
                     YTMGLLGLVALIFPLFILKEMEKKEKIIYVGVVSTWVCVTNLFPWFLFQKTPISLLQF
                     PWRILGIQIFFSSMIITLVFMKKTMNKKYSWLIIGATVVFLLVTSIAAKENYAKVIQS
                     KHGHIVINEETLPRYTTSDMGGLYDYAPTEAIKERPHLEKHEVKVGESWEKGKYKAAD
                     NNITYTVASNKKQKVTVPVYAYLGTQVKVNGKVVNDSYKKHGLVNVDVNAGENKIEIT
                     TKYTPTALMALWISILTYCLVVYSSFKRFAPNKLKDSRYVTKKEINKKNENK"
BASE COUNT        33514 a        23775 c        19598 g        36983 t
ORIGIN      
        1 tacatggtgt tcaaaatatt attcgccttt tgcttctttc actaattttg cgaatgcttg
       61 ttgttggaat tcagcagcta aggctttcgt acgttgttct tgctctgctt tgctcatttt
      121 tggattttca gtcattgctt ttaccatacc gtcttgaaca taagcttttg cttcactttc
      181 catcgtactt tgctgtttct tcactaattc agctaacttg gctgcttggt ccgtacttaa
      241 ttctacccat gtctctggga ttttgaatgt attcactcgg ctgtcatatt cgtgattgtt
      301 atcagcaata ttgaaccaga atttatacat gtcgtttttg tattcccaat aagtagtttt
      361 cgtcactttt tcagcatcgc cgtctgtctt ttctacttta tttgtttcgt tatccgtacc
      421 agttgctttt ggtttttctt gtttttcatt tgttcggtaa agatacactt tttcttttcc
      481 attccctaaa gctttataca aaagcatatc tgctccttgg gaatcagcac tggaaacaat
      541 tttttctgtt tttgtttccg ttactttttc cattccaaag tgattggaca aattagcgac
      601 gatcaaactt agtgaagcga cgaagattag tccgaaaatc aaagataaaa aggtttgcca
      661 tgttttttta gcgaacacgt tcgttaaagc aaaagcaagc aagctgacaa tcaaaactcc
      721 aataatcatg cattatcccc cgctttcatt agaacaggtt cttttttctt caataaaaag
      781 gcaataataa agccaagaat cccaaagatg atcgctacga taaacgcggc atggtaacct
      841 gacagtgtgg cattgattgc ctgatcttta taagctaatg gcgtattatc caatacagat
      901 ttgcttggga tatttgcttt tgtcacattc gtcaacacac tgatcaaaat agctgtacca
      961 atcgagcttg cgatttgacg gaatgtatta tttaccgctg tcccatgact gatcaagtta
     1021 tttggcaatg cattcatacc agaagtcgtt accggcatca tgaccatgga gatcccaaac
     1081 atacggatcg cataaaggat cacgatatat aaaactggag tcgtttttgt caagaaagca
     1141 aatggtgcag ttgccgctgt caaaatgaac atccctgtga tggctaaacg tttcgcgccg
     1201 tatttatcga aaatcgcacc cgtcacaggc atcatagccc ccatgatcaa tgcacccggc
     1261 aacaacatca agccagaatg gaatgctgat tctccacgaa tattttgaat atacaatggt
     1321 acgaccattt ctgcccctac catcgccata tttgttacac cagctaaaac agctgcaatc
     1381 gtgaatgtag atgatttgaa tacacgaagt tccaagaatg gatgttccaa atgtaattga
     1441 cgccatgaga acaaggcgat gaaaatcaca ccaacaacta agaaaccaat tactttcaag
     1501 cttccccagc cgtcatctcc tacactagaa aatccgtaaa gtaaactacc gaatccaatc
     1561 gttgataaaa tagcggataa aatatcaatg ctaggatttg acaatggaat aacacttttc
     1621 attaggaaga atgctaaaac caagacaaga acaacgattg gcagtaccat accaaacaag
     1681 tcacgccaat ggtagttatc aatgatataa ccagataatg tagggcctaa agcaggagca
     1741 agtccaataa cgatccctga catccccatt gctgatcctc ttttttctgg cgggaaaata
     1801 gatagcatga tattttgcaa taatggcatc gatactccca caccgcaagc ttggatcaaa
     1861 cgaccgatta gtaatgtact aaaattaggt gctgtaaagc aagtaatcgt tccgatcaaa
     1921 aagatcgtca tggcagaaag atataaattt cttgaactga atttattgat cagccatgct
     1981 gttattggga tcatgatccc gttgactagc aagaaaccag tcgttaacca ttgcacatca
     2041 gacgctgaaa tatcgaaagc tttcatcaat gtaggaaaag ctgtcgtcaa taaggtctga
     2101 ttcaaaacgg tacaaaatgt accaattaat aagacaacaa ctaaaagtgt ccgattatat
     2161 ggttttccgt aaatatctac gggttggttg ttactcatat ttctccttct ttctgaattt
     2221 tttctgaaac tactagaata ctttagtcct aaattcgcta tttgtcaacc tacttgacac
     2281 ataagttaat acggatataa ttaagggaag caagaggaca aaaggagtga caaaaatggt
     2341 tggggcttcc cttaaacgtt tgttggaaaa tgatcaattg gttgttggca tcagtgaatt
     2401 aagtgatatc gtaggtgtgt ctccacgtca attaaggtat tgggaacaaa agggattcat
     2461 tcgttcgatc gaagctgatg cgaattgtcc tagaaaatat cgtttaccta cagtcataaa
     2521 agtagaactg atcaaaaaat atttagatga cggatttact ttgtcaaaag ctgcagaaaa
     2581 ggcagaaatc cgccaaaaga aaatgcacca tgtccgtaaa gttttttcaa aagcaatcaa
     2641 agatatcgaa ttgatcgacg aacgctatac gattttacaa atcggtaact tcaaagaaga
     2701 gaatgctaag atgtacatca ttcatgacaa cgagacagac gaattaactt acaagctcct
     2761 tcctgtcgat gaaaaagctg actacgaaca gttgttaaaa gaactctaaa cgccactaat
     2821 ctcctaagta ccaagctttt taataagtag atgctacata aatacttgaa aaaaggcctg
     2881 tttgaacata agaatatccg aacggtgatc tgcgtttctt tcatatagaa aggaattctc
     2941 catcactgtt cggatatttt tttatttttt tcggttactt tcttctaata catctgttag
     3001 ccaatttgca tattctgttt cccgattgat cgcatgcgct aaaatcaggt agtgtccgta
     3061 attttcatgt ttttcttttt cagtaggaaa gatcgttttt tttcgctcta atagatgaag
     3121 tcgtttttct tcatgaaggt cacgctgctg ctgaataatt tctactaatg ccggatcatt
     3181 cacgtctttg acgaaataca atttcagaac aaattcgtct cgattaaccg gtagttcatt
     3241 ggtgggtgta tgaatccact ctgccaattg ttccttccct tcttctgtta attcataaac
     3301 tttcttttcc aatttttcac ctgtgatctc tacttgatgc tgaatgattc cttgctcttc
     3361 catttttgca agttcaggat aaatctgact atgttttgct tgccaaaatt ctcctatttc
     3421 atttttgaac gattgattca attcatatcc tgtcatcttc ttcttactta ataaccctaa
     3481 caaaatatat cgaagtgtat tttttcttgc catcagtttt ccctccttga caaatcttta
     3541 aatccattct atcataaatg agtaatcgaa aacatgtagt ttattacatg ttttaattta
     3601 taaggagatg cttaaacatg aaagaattta aagaattgga agattttatt ggaactcact
     3661 ttatctatac gtatgacaat ggttgggaat atgaatggta tgccaaaaat gaccatactg
     3721 ttgattaccg tatccatggc ggaatggtca aaggccgttg ggtaaaagac caagaagctg
     3781 atatcgttaa attgacggac ggcgtattca aaatcacttg gacagagcca acagggacag
     3841 acgtggcatt ggactttatg ccaaatgaaa agaaacttca cggaatgatc tttttcccta
     3901 aatgggttga agaacatcca gaaatcactg ttactttcca aaacgaacat atcgcagaaa
     3961 tggaagcagc tcgtgaaaaa tatgaaactt atccaaaatt acttgttcct gaatttgcta
     4021 cgatcactta tatgggtgat gcaggtatag acaatgaaga tgttattagc gaagaaccat
     4081 acgatggaat gccagatgat atccgtagcg gaaaatactt cgatgaaaat tataaacgag
     4141 taaaataagg ttgtgaaaga gaggttgtga aatcagcgtt ctgacctgag tattagagaa
     4201 agaaacggaa aaatagttcc tcatgttttg ccgttttttg agctaatacc gagggtcagc
     4261 tgattgaaca ccgtttatca agaggttgtg aaatcagcgt tatgctttga gtaataagaa
     4321 cgctagttag aaaatagctt ttcatatttt ctaggctagt gggcttatta ccgagaagca
     4381 gccgtttgaa caccgtttat caagaggttg tgaaatcagc gttttgacct gagtattaga
     4441 gaaacaaatg gaaaaatagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
     4501 agctgattga acaccgttta tcaaagattg taacaactgc atattcacac agttaaatta
     4561 gtgacttcaa aatgaaataa tgctcccagc aaaaaattag gctgggagca ttatttcgtt
     4621 attctgttca tcaaaaatca gcgttttgat tccatttcat cacaagttcc tcctcattta
     4681 ctgcttcatc tttttgctgt gtttgaattg taaaaccttg tgaaagatag aaatgaatag
     4741 ctgattgatt tttttgatag actgtcaaag tcagtgtttt attggtttct tttatttttt
     4801 tcattagttg cgtaccgatt ctttgttgcc ggtattccct tttcacaaag attcctgcga
     4861 taaactgatc aatcacccca gcaaaaccaa taatttcttg atctatttct gctaagtaaa
     4921 tcactgcatc tggtaaagct ttcctaacag attctacttg attctcccaa taagttgatg
     4981 gaatgaattc atgagaatcc aagttagcat gcagccaaat cgatagaaca gattccagtt
     5041 ctttggcaga caattttgtt gttgtgcgga tcattttttc tctccttact tattcattga
     5101 ttttaaaata aaaaccattt ttttgaagct cttttacaag ttttcgcccc tcaaaaaagt
     5161 atatcttctc ttgttttact tttctaatac caaaagaaac agcaacttta ggatcatcag
     5221 ctgaaacgat tcgataagtt ccaccaggca attgatccag cttgactttc ccatgatggt
     5281 cgctttgtac tgaaaacggc acaccatttc tagtaagtgt ttttttctta tgtttcaaaa
     5341 tgaatgaact accatttacc ggtttccctg acgaatcact aataataaat gaaaaatcaa
     5401 gcactttttt acttaatcta tactgataga ttagtcgtcc gataaacact aacagtatga
     5461 ctacagctat tatcgttcct gcaagaataa accattgccg catggttctt tcctgatttc
     5521 cttttccttc ttcttttttt accgattcgt tataaggaat ccgatgtcct gtcactagca
     5581 aacgatgcgt gttgatcata tacggcgtac atgtaagcaa ggtaactaag tcttctcctt
     5641 ctgaaatcgt tagaacagac gtgtcatctg gcagtaccac ttgtatattt ttaacttgat
     5701 aagccaattt ctcccccaaa acagtcaaaa taaacgtgtc tccgttttct aaacgatcta
     5761 attcggtaaa taaccgtcga ttaggtaaac cgctgtgagc agagatcact gaatgcgtcg
     5821 aatttccacc aagcgggaaa gaggttcctt gcaagacgcc tgctccattt tcaaggatcc
     5881 taccattgag ccgatcataa agtgaaatat ttaattggat cttaggtata ttgatacttc
     5941 cgatcagcca ttcctctaat tggctggatg ttgtactttc atttctgttc ttttcattga
     6001 aaggatcagt accaggattg aatccttggt cagttaatcg ttggtttttc tcctccattt
     6061 tctttcgctg cacttcaatt tcagctgcgg tccgtttttg tacttgttcg atacgttttt
     6121 gatcaataaa actatttaaa gaatccacat aaaatggata taaagcgatc agtaacccta
     6181 cgacgataca tattaataaa aacaaacgaa acaaaagtcg acgagactgt ttttgcttac
     6241 tctgcttcac atgtgtcctc ccttgcaagt ttttttgttc tttcttttat tatatgggtt
     6301 caggaaaaaa atagaaaatg aaagccgatg aggttgtgaa aaagctgtcc tgcatcaagt
     6361 aataagtaca gcccaaaaaa atagctactc atattttttg ttgggttggg cttattaccg
     6421 cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gaaaactgcg ttatgctttg
     6481 agtaataaga gcgctagtca gaaaatagct tctcatattt tctaggctag tgagcttatt
     6541 accgagaagc agctgattga acaccgttta ccgagaggtc atgaaaaagc tactttgttt
     6601 cgagtattaa gaaaaattct gtttcaaaac aaggagatgc aacaaaactt atgtcgcatc
     6661 ctctctcctt agaactttca cttatgtttt tcttgtaaaa ttcataaata ttttcatgaa
     6721 ttttctaatt tcttgcctac ctctcgcata ggatatatga tgaatttatc taaagtttgc
     6781 aaaggagttc gacaattgaa aaaatatggc ccatttttag caattttttt cattgctttg
     6841 gcatttctca tgcctcattt attcacacat aaactaattt tgggtgctga tgccccattc
     6901 cattacaatc ggttctatga tgccgcgcaa caaattaaat atggggattt ccattatttt
     6961 ccttcccttt atggattcca gcaaagtggc aggatcgtga atgccgttta cggcccattt
     7021 ttcgcttatt tacaaggatt gatcgtgttg cttgcaggta gctggtttca ttatcagatt
     7081 ctttcaaatt tcattcttta tcttatttca ggattttcta tgctgatttt actgagatat
     7141 gtcaatgttc gaaattgggt aagtgtacca gtagccgttt tattcatgag tacgtattct
     7201 attcaatact ggtctatcaa ccaaggattc actagctggg ggacttgttt ttatccttta
     7261 tgtatgatcc ctattgctga tttcgtcctt cataaaaagt tccctgttat caaagtcgct
     7321 gtctcagtgg gacttatgac acagatccat ttactgtctt cgatcatgtt agctttgatg
     7381 tatatccctt tttatcttta ttactttttt aaccagactg aaaaaggaaa agcactgctt
     7441 caactgatta agtcggtctt gctttatttt gttctgacag caaatatttg ggcaggatta
     7501 gctattgttt acagtgggaa taagattctt cctccctttg ttaacagaga aatgagtcaa
     7561 aaggcgatag atctggatgg cagttattgg ctccattacc ctaaggcctt tcctatattg
     7621 atattatcag gttttttgct ttttattttc tttcaacaaa agaacacctt attccaaaaa
     7681 atcgtgttgt acacaagtct tgttttcttt tttctttcta ctagcttgat tccatggacg
     7741 acattgatcg aaaaaaatgt gccttttatt agtttgatcc agtttccatt tcgatttttc
     7801 gtgccattta cgctattgct tctactttac cttgcccttt cactgaacca gtggtctgaa
     7861 caaaagtggt tccgtctttt aagtatattt ggcattctta ttttttcagc acagacgatc
     7921 cagaacttat accagcatct ggaaaagtgg gaaaatgaaa catttgtcag tcgacatact
     7981 tatctattcg atacgccgga agaagcaagg aaaacattct tcagcaaaga tatgtctacc
     8041 agcttgttcg ttttccaaaa aaccacacct gactatctgc caatctataa ggagacaaaa
     8101 gacaataaat acgaccggta taacgaagaa atactagaaa acgaaacaac ttttataaaa
     8161 acacatccag gcggtctttt gacaatcaag tggaaaaaca ctggggacaa aactgttcat
     8221 atccctgtta tcgtctacga tcggactgtg ctacagcaaa atggaaaaac attgactgat
     8281 tatgaagtaa cagatatcgg gaccccaatc gtgaagcagc aaaaaggaat caacgagctc
     8341 acgcttcatt atcaaacgcc aatctatttc tatttcattc tttctcttac tttgattggc
     8401 tggtttacct tgctatgttt atttatttat catagataca agcttttacg tgcttaggca
     8461 aaagggataa atacatccga tcaaaaaact ctccaaacgg tataatcgtt tggagagttt
     8521 tattttaatc agttttttta tgttatatgt tatatttttt attcgttcac atctaattcg
     8581 atttccaccc cgtagtgatc actgatgatt ggactatcga tcccatcaaa aatccgttga
     8641 tattttttaa cctgcattcc ttcagggacg aaaataaaat ctatacgcaa tttttctgta
     8701 ttttgttccc aaccatctat tttcttttcc acagtagctg cttttccttt ttcattcgcg
     8761 acaacatacg aatcttgaag aagaaggcaa ctttctctta cagtataata accttgagag
     8821 tctactggat tattgaaatc acctaggaaa aaaagtggta cgcgagtttc caaaaagtag
     8881 ttttccaagt ttttccactc aaaataaaag ccactttttt tatctgtcca ccaagaaaag
     8941 tggcagctcg agacaaaaat gtcctgatca tctatctttg ttttcccaat caagatcttg
     9001 cgtgtctgat aatcttcttt cttttgaaat tgggagacgg taaggacctg actttccaat
     9061 gtttttttcg taagcagtgc atttccttct tcatatttat cataaccgat gtggctcatt
     9121 tcccaactcc aaaaatactc ttttccgtgt tcctttaaaa gctgaactaa acggtaggca
     9181 aaattatctt tacggatagg tacttgattc tttaccggac agaacttcat tagcttcgca
     9241 ggttctactt cttcagattc cagtaattgg ttgatttctt gtaaagcaat cacttcataa
     9301 tcttctaaca ggatcttatc tgctaattct tgcaattttt tctctggttc tggctcaagc
     9361 cagctatgcg tgttgagtgt catgaatttc attggttttc tccttgtctt catttcgaaa
     9421 caaaagggtt gtgacaaaat ttttgtcaca acctctccag caaatagtgt tctcctgcta
     9481 actcctcagt aataagctca atggaccagg agctattttt tgtttggctg tttttatcac
     9541 ttggtgcagg gcagcttttt cacgacctct ccactaaaca gtattcaaac tgctgcttct
     9601 cggtaataag cccaaccaaa cgaaaaatag gaggagctat ttttgtttgg ctgttcttat
     9661 gacttgatgc aggacagctt tttcacaacc tctccttaca ttttaatgga gccgatcact
     9721 ttaccagctg tcactgtacc taattgcttg atcactactt cttctacttt atcgtttgta
     9781 aatacgatca tgatcgttgg atctttttct tcgttttgga tcacatcaag atccatctca
     9841 gctaatttcg ttcctgttcc tacttcttgg ccttctttga cagcaatctc aaaagctggc
     9901 tgattcattt ggactgtatc gattcccata tggatcaaaa cttcgatacc atctttcgtt
     9961 tccagcccaa ttgcatgttt gctagggaaa atacttgtca cttttccagc gatcggcgca
    10021 acaacttctc ttgatgttgg aataacagca aagccgtcac ccatcatttt ttgtgagaat
    10081 accggatctt ttacttcaga taaaggaatc acttctccag aagctgcgga aactagttct
    10141 tgttctatac ctaagtattg cttactacct gcttgtccat ttcctgtaga aaccatttct
    10201 ggctctggaa tctctgctcc tgattgcagc agatcttcga tatctgattt caagacatct
    10261 gcttttggtc cataaactgc ttggactcca ttgtctttga cgatcaatcc catcgcccct
    10321 gctcgtttcc aggcttcttc agtccctact ttttctcgat catttacact tacgcgtaac
    10381 cgagtcatac aagcatcgac atctttgata ttttcttttc ctcccagcaa atgaatgatc
    10441 tggaccactt gctgatctgc tgttcctgtt ccgctgttag atacaacggt ttcttcactg
    10501 tcattgtcgt aatttccgtt acgtcccggt gtagcaaagt tgaatttttt gatcaagaaa
    10561 tttgctaaga aatacgtaac aacaccaaaa gcgatcacac acaacacgaa gttgataaga
    10621 tctccaccta gacccgcttt gatagctaac ggtgtccgag tcagcaattc gatattccca
    10681 aatgaatgga cccgcaatgg caagatatct gccatcgcaa atgcagcccc ttggatcact
    10741 gaataaatga catataatgg cacagcagca aacataaaca tgaactccaa tggttctgtt
    10801 acacctgtta gaaagacagc caacgctgct gaaaaataca ttgatttata tcttgctttc
    10861 ttatcaggat cgacattacg atacatcgca aaagccattc ccatcaagat acctgaagaa
    10921 ccaatcattt gtcctacttt gaaacgagcc ggcgtccagt tatgcaacac aaactcatat
    10981 tgcgacatat cccctgcacc tttaagattc actaaatcag tggcccaagc caaccataac
    11041 ggatcttgcc caaatacttg tgtccccgcc tgtgcgcctg ataaaatctc atacgatccg
    11101 ccaagctgtg tatagttgat aggaatcgtc agcatatgat gcaatccaaa tggcaatagt
    11161 aaacgttcta atgttccaaa taaaaacggt gctagaatcg gtgcgctttc ttgtgattct
    11221 gcaatccata aaccaaaatt attgattcca gcctgtacgt ttggccacac cacagcaaga
    11281 atcaatgcca cgattgttga ccataagata acaacaaacg gaacaaagcg ctttccattg
    11341 aaaaatgaca aagcatccgg caattttcta taattatagt acttattata agccattgcc
    11401 ccgacaaatc cagcgatgat ccctacgaat actcccatat tcaaagctgg tgcttccaat
    11461 acacttgtaa aaaatccttt aaccatgatc ttcgtaccga acagagtgtg ggtaaatgca
    11521 tcttcattcg caagcatgtc acttgtgaca ccaaagatag ccccagtgat ccgattgatt
    11581 aaaataaatg agatcccagc tgcaaatgct ccgcctgctc tttcttttgc ccaacttcct
    11641 cctattgcta aagcaaataa aatatgaaga ttaccaataa ttgcccaacc aatattttca
    11701 attactccgc ccgttgtgac aagcggcgtc caatcaggat tgatcaaggg aattgatttc
    11761 cctatactga tcatcaaccc agctgccggc ataactgcta ccacaaccat taaagccttt
    11821 ccaaattttt gccaaaactc aaaactaaat atctttttca ttccgtttag ctcctttacg
    11881 caatcggttt cgttaaacgt attatagcgt gcgttttctt ttttgtaaat gctttatttt
    11941 ttatttttct gtctatacca ttctataaaa cctataatac gtgtgttccc ttctataatt
    12001 ttctcctaaa aatttatttt tttaagcttt tttctatgaa atattttctt ttgtctattg
    12061 acttgtgcaa tcggttgcgt ttattatgaa cgtataaaac agctcattag gaggagaaaa
    12121 atgaaacaga tcaaacgact atttgctatt gatccatgga aaatcagcac gacacaatta
    12181 gataaaaaaa atcttcgact gcaagaatct ttaacaagta ttggaaacgg ttatatgggg
    12241 atgcgcggga actttgaaga aacttactca ggggaccacc atcaaggtac ttatttggcg
    12301 ggtgtctggt atcccgataa gacacgtgtc ggctggtgga aaaatggtta tccagaatac
    12361 tttggaaaag tgatcaacgc cttgaacttt atcgcgatag atatttcgat caacgatcag
    12421 ctgatcgact tggcttcttt ggaaccagaa gacttttact gggaattaga tatgaaaaat
    12481 ggtgtattat ctcgtacatt cacaatcact acttctacta ataaagtacg catttccttc
    12541 gaacgttttc tgagcattgt caaaaaagaa tcagcttata tctatttaac tatagaaatg
    12601 cttgaaggta gcggaacagt caaactcgta tcaaaattgg atggaaatgt tcaaaacgaa
    12661 gacagcaact atgatgaaca tttttggaat gagattgatc gtggaactat agaagaaatc
    12721 ggctatttga cgactaaaac tattccaaac aactttggga ttgaacaatt tactgttact
    12781 gcagcaatgc gccatttcgt taatggaaaa tcagtcatcc ctgactatca cgaagatact
    12841 ttagcattac atggttgctt gtctgcagaa ttatctcaag gtgagacatg gtcagtggaa
    12901 aaagaaatta tcgttcttac tagtagagat attccagaag cgcagcaagc agaaaaagct
    12961 gtctcagaat taacgaacca gacaaacaat tatatccaag caaaagaaga gcaaacagcg
    13021 gcttgggcag aacgatggaa gcttgccgat gtggtcatcg aaggagacga agaagcacaa
    13081 caaggtattc gattcaattt gttccaacta ttctctactt actacggcga agatgaacga
    13141 ttgaatatcg gccccaaagg attcacagga gaaaaatacg gcggagccac ttactgggat
    13201 acagaagcgt atgctgtccc tctttatctt gctttagcca aacctgaagt aactaagaat
    13261 ctgctgaaat atcggcataa tcaactgccg caagcaatcc acaacgctca gcaacaagga
    13321 ttaaaaggcg cgctttatcc tatggtcacc ttcactggtg tcgaatgcca taacgagtgg
    13381 gaaatcacat tcgaggagat tcaccgaaat ggcgcgattg cctatgcaat ctacaattat
    13441 acgaattaca ccggcgatac ggaatatttg aaaaatgaag gactggaagt tttagcagaa
    13501 atcgcacgct tctgggcaga ccgtgtccat ttttcaaaac gagcaaataa atacatgatc
    13561 cacggtgtga ccggcccaaa cgaatatgag aacaatatca ataacaattg gtatacaaat
    13621 acgatcgcag cttgggtctt gcgttacacg cgagaaaatt atttaactta tcaaaaagaa
    13681 gctgctatca ctatcagcga agaagaacta gccaaatgga aagatatcgc agagaacatg
    13741 tacttcccag ttgacgaaga attaggaatc tttgtccagc atgacacatt cttagataaa
    13801 gatctcatgc ctgtatccga tattcccaca agcgatcttc ctctgaatca gcattggtct
    13861 tgggacaaaa tccttagatc ttgcttcatc aagcaggcag atgtactaca ggggatttat
    13921 ttcttcaatg atacttttac aaaagaagaa aagcaaaaaa actttgattt ctatgaacca
    13981 atgactgtcc atgagtcttc cctttcgcca agtatccatt cgattttagc agcagaatta
    14041 ggaatggaaa gcaaagctgt agaaatgtac cagcgaacag ctcgcttgga tttggataat
    14101 tacaataacg acacagaaga cggcttgcac atcacttcca tgactggtag ctggttgtcg
    14161 attgtccaag gatttgctca aatgaaaact gcccatgatc agttgagatt cgcaccattt
    14221 ctgccaaaaa cttggaaagc ttattctttc catatcaatt atcgcggacg tttattgttc
    14281 atctcagtca cagatgaaca agttactttc aagttattag aaggttctcc tctagaaatt
    14341 tacgtctatg aacagtctta ttctttagcg gatcgtctag aaataacgct aagaaaggag
    14401 gaagcaaatg tttaaagggg tattgtttga tttagacggt gtcattaccg atactgctga
    14461 attccattat cgtgcttggc gaaagcttgg tcaggaaatc ggcattacga tcgaccacac
    14521 attcaacgaa cagctaaaag gcgtcagccg agaagactca ctctctttgc ttttagctta
    14581 tggcggaaaa gaacactctt ttacaaagga agaatttgca gaattagcga aaagaaaaaa
    14641 cgattattat ttagagatga tccagacgat cgaaccaaaa gatgtcttcc ccggggtcgt
    14701 gcctttactg gattctttaa aagaagaaaa aatcaagatt gctcttgctt ctgcaagtaa
    14761 aaacgggcca ttcctacttg aaaaaatggg tcttacacct tactttgatg ctattgccga
    14821 cccggcagaa gcaacaaacg gaaaacctgc gccagatatc ttcctccttg cagcaaaagc
    14881 tgtcggacta aaagcagaag aatgtatcgg gatcgaagac gcgcaagccg gtatccaagc
    14941 catcctctca agtggcgctc aaccaattgg cgtgggacgt gctgaagacc ttggagagga
    15001 gatcccgctt gtccctgata cgacttttct tacgatcgat tacttgaaag aaaagtggca
    15061 tgaccatgga taatccagag atctccgtcg taccagttcc agagactgaa ataaagaaaa
    15121 tcacattgaa gaacgactac ttagaagtcg ttcttctcaa ttacggtgcc cgcctgcacc
    15181 aaatcttcgc accagacaaa gaaggaaaat cagaaaatgt tttattgtct tacgatcgtt
    15241 tcgaagatgt tctaacagac aaaagctttt ttggagcaac tgtcggacct gtagccggaa
    15301 ggatccggga tgcttcttgg ggtgagcata gattggagaa aaactgcgga tcacaccata
    15361 tccacggtgg cacgaaaggc tggtctttcc aattttggga agtagaagtt ttcaaaactc
    15421 catcatcaat aggtgtggtc ttttacttaa aagatgaatt ttctacctat ccaggaccaa
    15481 tcactgctac gatcacttac cgtttaacaa aaaacgaatt agagatgaca acctctgcta
    15541 gtagccttgt tgaaaccatc tgcaatccga ccaaccatgc ctacttcaac ctttcaggaa
    15601 atggaacaag agacatctat gaacatcagt taacggtctt tttagatggt gtgcttgaat
    15661 tagatcaaga aaaactgcct actggaaatt ggacaaaaaa agaaaaactg ccaatcgact
    15721 ttagaaaatc cccaacactg caagagatcc ttgcatgtta tccagatgga ctagatgatg
    15781 tatttctttt gcatcatcct aggctttcca aaacttcctt acaattattc gagaagcatt
    15841 ctggtcgcca aatgactata gcaacttcta ataaaagtat ggtattattt tctacgactg
    15901 gattcgaagc tgatttctct gtcaatggaa aacagatgca ttcaaactac ggattagcaa
    15961 tcgaaccgca agaaatccct gatatcgttc atttccccaa atttggatcg atcaacctcc
    16021 atcctggtca agaacggatc agtcagacga tttatcggtt ctctgcacaa taacaagaga
    16081 aaggtgtttt tatcatggct attaccgtaa aagatgtggc gaaaaaagcc ggtgttgcca
    16141 cctcgaccgt ctctcgtgtc atcaacgatc atcctagtat ttccgagaca acaaagaaga
    16201 aagtccgaaa aattatggat gaactaggtt atgttcctaa catgactgcc cgcaatctag
    16261 gaaaacgcat ttccagtgcc atcggcgtaa tcttaccccc tcttgattca aaagagcgga
    16321 tcggtaaccc attttatctt gagatcatgg aagcaatcaa cgaagaagcg cggaattatg
    16381 atatgactac agcaatcgct actgctaaaa attttgaatt gctgttagag aacgtccagc
    16441 gtatgcattt acaaaaacaa gtagatggtt ttattctagt gtattcagat agtcaagata
    16501 ctgtcattga ttatttatac caaaaccaca tccctttcac tttgatcgga cagccttatc
    16561 atcatgagaa cgaaatcgtt tatgtagata atgataacca gcttctaggt aaacaagcaa
    16621 cagaattttt gatccagaat ggacataaga atatcctgtt tgtgacaaac acgactcatg
    16681 aaagtttgta tttcgaacga tatttcggtt atcaaaaagc aatgatgatg gctggtcttc
    16741 ctgcgttatc cagtgtagta ctagagcatc cggaggatta tctgtccttt gagaaaacgt
    16801 tgaaagaaaa cgaagccaca gcattggtgg tcattgacga tatcttcgcc cttcgcacga
    16861 tgcagttggc gcaaatgtat ggctatgtca ttccagagac actctccgtc attagcttca
    16921 acaactcgat cttctcaaca ttaacacacc cttaccttac aagtatcgat atcgatatct
    16981 ccgaattagg acgtgtcgct atgcaaaagc tgcgcgaatt gatccatgaa gaattgagca
    17041 gtggcgtacg tttggtcatc cctcatcgct tgatcaaaag agagacagtc gttcctttag
    17101 aaaacccata ctaaatagct gactcactaa atacgctgac catttatcct atggtcagct
    17161 ttttatgtaa aagaagatac tacttctaac acattgttta tctgtaaaaa agagcgtggg
    17221 acaaaagtaa agaacacttt tgtctcacgc tctaaacacg tataaacggc ggaagcagaa
    17281 gcaactcctt cggaaataag ctgaaattca caaaaattta aaaagcaatt ttcttgagtt
    17341 tcttcttatt tcttggagtt aaacgcttct gtcccagcct cttttttcct tccttcaatt
    17401 ttttacacgt cgacgattca ataaaaaacc gcctaatatt gtaaagacag gtgcaagaat
    17461 cgagaaaaag gcgaatggca agtaatgcaa cgcgctaact ttcatcgttc ccataatgaa
    17521 tgtgccgctg actccccacg gtacgagaga attgacggtc gcacctgaat ccgctagtgt
    17581 tcgtgtcaaa taggtttttg ataagccaac gtcatcaaaa gaacgcttga atgtttctcc
    17641 tggaagaatg atggacagat actgttctcc aacgatcaga ttgattccga tacagctcaa
    17701 ggcagtaaac ccgactaaac gagaaggtcg gtccatcttt tcttttaatt cttgaacgat
    17761 ggtatcaacg atcagatatt tgatcagtaa cccacctaat gccaatgcaa gtaaaatcaa
    17821 actagcagaa cctaacatac tcatgatccc gcctcgagaa agcagttcat ctagctttgg
    17881 atcaggtgta tttgcgacat aaccattcat caagatgtct gctgcttttc cgaccgtcaa
    17941 acttttctca tggataaaag aaagaacgag agcagctgtc gatcccgcta gtaatgtagg
    18001 gatagccgga atttttttga ttgccccccc caaataaaat aactagtgga atcaatgtcc
    18061 aaggagagat ccaaaagctc gctttcatgt tttggatcat ttcattgata ctagctagat
    18121 cggctgaatg actgttatgt cctaatatcg tataaaaaat caacgaaagg acgaatgctg
    18181 ggaaatccgt ataacgcata ccagcgatat gttcgaatag attaactcct ccaatacccg
    18241 ctgccaagtt ggtcgtatct gataaaggcg agcagttatt ccctaaaaag gcaccggaaa
    18301 cgactgcgcc tgtagtcatt gcatcattga atccaagtaa atgaccgatc cccaaaaaag
    18361 caattccaat cgtcgaaatc gttgtaaatg aactgccgac agtcactccg acaattgcac
    18421 aaacaagaaa tgctgtcggt aaaaagaaac gcacagaaac aagtttaaat ccataaacca
    18481 taatcgtagg gatggttcca gataaaatcc atgaagcaac taagacacca atcaaaagaa
    18541 aaatcaggat tggaatgatc cctggagtga ttcctttgat gatcccgtca tggatctcat
    18601 cccatgtgaa ctttttaaat ctgccataaa acaacaaaca catgaaagct gcaaggatcg
    18661 ggatatgtgg cgagagctgg aatccgatga tcagtactcc taggagtgcc aacaacacga
    18721 tcaatacagc gatactttct tttaaagaaa tatttttatt catcgtcgat ctcctatttc
    18781 aaatgaaaag gccctgccat gaaaaaacta ttcacttggc aggacctcct actaaatcag
    18841 cgacaaaacg tcggctgaaa gacttatttt tttatttttc ttctaaactt ttttctacct
    18901 caatccccca agaatctttc ttgaagtgat tgatgatcaa tggaataacg aacatgacca
    18961 ctgtgatagc tgctactaat aatgcatcac tcaatgtcgc tgtacctaat gtagcaaata
    19021 cgacaacgat gatagagaag atcagcatgc agctgactac ccaagctaat ccgtttccgt
    19081 ttttaccaat tcggtaagga cgttcgaatt ctggatgttt cttacgcatt ttaagcaatg
    19141 aaacagcaat caaaatgtac acgatacaat aaataacagt tgtagcattt gtaagtgtca
    19201 agaatacagc acttacgtca tccattacac cataaagcaa agcaaataat gaaataacga
    19261 ttgattgtgt tagaacgaca tttctagata cgccgtattt gttttcttta tggaatccga
    19321 attttggtgg aaggaatcct tcacgagcta cttggatgat tgtttttgat ggtccagtaa
    19381 cccaagctga taattgtaaa agcacaccaa taaataccat gaagctgaag atatttccga
    19441 tcacttctgg taagcctagg atttgacagt caatcaagat aggctgcgtg atatttgcta
    19501 attccatttt tccatctggt acgacatttg ctacaagcat cgcattgatg acattcaata
    19561 aaactaatcc gatcaaagcg ataaatacgc cttttgtata attttttgtt gcgtctttca
    19621 aacgaggcat gtaaacagaa ctcatttcga tcccaacaaa aataaatgtg ataccagcta
    19681 agtatttcaa tgaatcaata tgttccaagt cagggaaagc ttttgaccat gaaaagtcac
    19741 ctagatagcc gtttgagact agtccgactt tgaaggctgc caaaacacct aaaacgaaca
    19801 tgatgactac tgggatatat acccctagcc atacaccgat gttcccgccg acttttgcca
    19861 tatcgaattt caagttcaag atcgtgatga tccagtagat aactaaaata caacctaaaa
    19921 cgaaccagtg attattgcca agttctacat taccaaatgt gtttcctaac aatggtccta
    19981 aagtagaagc gaccattacc atacctggga acatttgcac ccataatagc catgcaacga
    20041 caaatcccca tttgctgccc agtgctgttt ttacccataa ctgaggaccg ccttcttgag
    20101 gaagcatcgt ggaaagctca ccggaaacca ttgatatcgg accggcaaaa aacaaaactg
    20161 caaaaattga ataaaaaatc aatgtccaac cgactgcggc taacgtagga atactccgaa
    20221 ccgttgcaca cagtgccatt gtcagaccga taaaggtccc aagacccatt ttacttactt
    20281 cagatttact caccgttgac actctccttg attttttgga taaaataacg gtgtctttga
    20341 agtagtttca gcaataaacg aaacaattca gcgaatattt gaggggattc tttgagttta
    20401 ttgcttgaag ggtttcttca aagacaacct caaaacaaag ggatcgaaga gcttaggtct
    20461 ccccttgctc ttcagatcca aacatgcgtc agaaacagtt agtattcaag ctgttttcta
    20521 acatgattac cttgcttatt ttgcttcgct tgccaataat tggtctgcgt agattttttc
    20581 caatttttct tgaagagctg ctttgatttt ttcagcatat tcttcaaagt gttcttcttt
    20641 gttcatgtat ggtgtcatta cgctggcacg caatacagtt acttttccgg cacggttcca
    20701 ttcttcatct gagaatccta gttggttcac aaattgtaat gggctgttgc catagtctgg
    20761 gatagcaaag tcagtatgtg aagttaagaa ctcattaccg taaatgcttc ctttcacgta
    20821 tgaagaataa tcatatacgt catggttcaa tttattcatt gcaactaagt catcgttgcc
    20881 tttttctttg aatacatagt ctaccatatt gaaatctgga taagttaatg gatgaacttc
    20941 gatttctttg tctcctactt taaatgacaa gtcattcaag aagttgtaga aacgatgtgc
    21001 accttcgatt gatgcaccca ttaatttacc atatcctgtg acattcaaag gtaagacatg
    21061 gtgtgctgcc caaacgctgg ctgctgttgc ccctgctttt gaaccttcca agatataagc
    21121 cccaagtaat gctgggatat ctgcgccttt ttcaaataca tatgtcgcaa agtaagagat
    21181 aacgtctctc atgcggatat ctttgatgac gataccaccg gcagaatatg gaacatagcc
    21241 cattttatgt gggtcaatcg ttacagattc tgcttcttcg attgctttat atgcactgtg
    21301 tacttcttct aagatataat ctttgttttc tgtaaagaca ttgtatttgt aatgaacatc
    21361 ttttaaatct tcaaatggaa tgaagttgtt gtcttcgtct aagaaaatcg cacggccgta
    21421 tccgccataa gcagcatcta cgtgtaagta gaagtaaata ccgtcttttt ctaatacgcg
    21481 acgcaatgca acgattttat cgataccgtc gattgctcct tcttctgttg atcctacaac
    21541 accgactaca cctaggattg gtgttttttc agctgctaga ccacgaacga ttttttcaag
    21601 ttcgttgatg tccatgcgat agttgtggtc aactggcact ggaatcactt ggtctaaacc
    21661 gataccgatg atgtcggcag cttttagcca tgaatagtgt ttagtttgtg gaaccaacca
    21721 ttttcctaat ttttctaaat gttttccgct acgtgctgag tgagctttga tttcgtcgat
    21781 tttttctggg acgctgtcta acagattcat gatttcttct gttgacaagt tcattaattc
    21841 ccaatcgctt tttccagcaa ctagttcagg tgtcacttct ttcattgcaa gcggcaatga
    21901 tttgatgttg cgggcatacc aaagtccttc taagtttgct aaagaaccat cagcaacgat
    21961 gtggccccag ccatctttat agctcattaa ttttgcaaat tccattccta cttcttcttc
    22021 catttggctt gttgcaggag aagattcata ggcaacgtta ttaccattcc atagcatagc
    22081 aaaattgtac gctagtaaag atggcatcaa tgtttcagag ttcatatgac cccagtaacg
    22141 tccggcatta tgccaaggaa cggaatgggt acgcatccgc gctgaaattt ctgatagaac
    22201 atcctttgtt ttattcacag tgtgttcaaa actagcactg cttttttctt ctggcgtaat
    22261 aataggcatg tcttgaggca tgtagttttg acgccagcct aaatgttcat ccaccaattc
    22321 attcaacaaa gctttataga tttggccgtt ctcagctttg tccccaatga atagggcatt
    22381 taggtttaga tctttcgaca atgattcact catagtgaaa ccctcctaaa aaaatattta
    22441 aattttgtcg agccctacat tacacctgtt cttctattct gtaaactaag ttttggcctg
    22501 atttttaatc atattttaat atgtatcaat tatccgaatt gttcacactt ttgaaataat
    22561 taaaaaaaac gagggaattt acaaatgtaa actccctcgc aaagattgta ttaacgacaa
    22621 ccagcgttct attttaggat gggtttcaaa attggaatgt tgtaatagta tttccctttt
    22681 tcaaggtaaa aacttactaa attctaatca attactttgg ccaaaaagta atttttctta
    22741 ccttttcgaa taaccacaaa cttaccatcg aattcatcgg atggatttat gacaaaattt
    22801 aaatcggtaa cgcggtcacc gttaatactt atagctccgt ttgaaacatc ttcacgtgct
    22861 tgacgtttag atggttcaat ttttgtggaa acaagcagtt ccacgatatt ttcaggtgtg
    22921 cttgaaattt caacgttcgg cattttaccg aatccttgcg cgatttcttc cgcatttagt
    22981 tctttaatat ttccagagaa caatgcttgc gttatttttt gcgcttcttt caagtcttct
    23041 tcactatgca caaatcttgt aacttcttct gccaaacggc gttgtgcttc acgtttctca
    23101 ggttctgtct ctactttttt cgctaagtct tcgatttctt cttgagacaa gaaagtaaag
    23161 aatttcaagt atttcactac atcgcgatca tcttgattca accagaattg gtagaactca
    23221 aatggtgaag ttttcttcgg atcaagccaa acggcaccgc ctgcagtttt tccgaatttc
    23281 gttccgtcag ccttcagcat caatgggatc gttaaaccga acgcttctgc ttctggtcct
    23341 tctaattttc ggattaggtc taatccagct gtgatatttc cccattggtc tgctccaccg
    23401 atttgcaatt gcacatcgta tgttttatgc agatgcaaaa agtcgataga ttgcaggatt
    23461 tggtaagtaa actctgtaaa tgagattcct acttccaaac ggctggcaac gatatctttt
    23521 gctaacatcg tgttgatgtt gaagttttta ccgtagtctc tcaaaaattc aagtaaagag
    23581 atttttgaca accagtcgta gttgttcaca aatgtgatat ttgcatcttt accaaacaat
    23641 tttctcattt gattggaaag tgcgtccacg ttatgttgca cttgttccat cgtttgcaac
    23701 acacgttctg ttttgcggcc gcttgggtcg ccgatcgttc ctgttccgcc gccaatcaga
    23761 atatatggat gatggcctgc caattggaat cttttcatca tcataaatgg aatcaaatgt
    23821 ccgatatgca tcgaatcacc agttggatca acgccgcaat aaagtgaaat gctcttttct
    23881 tcaacgagct cgcgaagtct ttcttcgttt gtttgctgat taatggcgtc gcgccaagtt
    23941 aattcatcaa taatattcat tttactgacc tccgtgtagt ttttttatga aagcaggaac
    24001 ctgctagcat gtgtaattaa ttatttcttc aggataggat aggaaataaa aaaagtccct
    24061 tggcatataa gccaagggac gaaatctcgc ggtaccaccc aatttgtatg tctagatatc
    24121 caacatacct ctcgaacatt taacgctgtc gcgtggcaat cactgccaaa gactcctgaa
    24181 atgtaattcg ctttaaagca tgtactggtt tgcagcgacc accagctttc tgaaacattg
    24241 gctttaacaa ctacttcgtt tcgatcttcg tcttgttatt attaatatgt gtctatcata
    24301 gagcgcaact ttttctttgt caacagaaaa aggatatttt ttttaaattc ctcatttttt
    24361 cttttttgaa tccgctctaa ttccgaacat tttattttca attattgtta aaagaaataa
    24421 ctttttctgt attttttctg caatttatcg agaagtcact ttactttgcc tcttattctt
    24481 tcttcgttac aataaggaat gggacaagta aaaaaatgaa aaagcaaggg acgaggtata
    24541 tggaaaaaaa gcaaaaaatt attttaggag ccacttctgc tttaactatc gttattttaa
    24601 ttctaagttt gttttttgtc atccgatcat ctacaaaaaa agaaccaatc attcctgaaa
    24661 aaaaaataac agaaaaagca aaagaaccga cagatgataa gcaacaacta gttactcaag
    24721 caaaaaatct ggctcaaagc tacgattatg accaagcgat tgcgttattg gaaaaagata
    24781 gtaagaacgg atctactgaa acacaacagc ttcttcaaac actaaaaaag gagaaagaac
    24841 aactgatcga ctggtctgat cctactcaga tctctcatgt ctttttccac agcttgatcg
    24901 tggacccgca aaaagccttc cactctcaac aggcacaagg atacaaagat tatatggtga
    24961 ctgttgaaga attcaaccgt tcgatcgaac aactttatca aaatgatttt gttttagtta
    25021 atttgaatga tttgatccaa aaagacgaac aaggaaatct ttcctttaac gggcttgcgc
    25081 tacctgaagg aaaaaaacca ttggttcttt cacaagatga tgtcagctat tatgaatata
    25141 tggataattc cggttttcct agccgattgg tcgtatcaaa taacaatgaa atcaaaaatg
    25201 tctataaaga gaaagataaa gaagaaatcg gtgactttga catggttcct ctgatcgatg
    25261 cctttgtcaa gaaacatcct gatttttctt atcgaggcgc aaaaggtacc ttggccctga
    25321 caggttacaa cggagtttta ggttatcgaa catcaaaatc tcaatatgga gacaatgaaa
    25381 aaacaaaaaa agagattaaa gaagctaaaa aagtggcgga acagttgaag aaagacggct
    25441 ggagctttgc ttcccataca tggggtcact tgaatatgac tcaagcttca ctagaagatg
    25501 taaaaaaaga caatgaattg tggcagcaag aagttgcacc tatcctagga aaaacaaata
    25561 ttctgattta tccatttggt gcagacatca gcgactggca gccttattca gcagaaaatc
    25621 aaaaatttgc ttacttgaag agtcaaggtt tcgatatttt ctgtaatgtc gatgcttcta
    25681 caccagcttg gggacaatta ggtacggatt tctatcgaaa tgctcggatc aatatcgatg
    25741 gcattcgttt tcaatctgat ttagacggaa aaaatcctat tcttgatcca ttcatcaatg
    25801 tccatgatgt ctatgacaaa gaagcacgcg aatctgcttg attttacgtc atttatgaac
    25861 caaaaaagcc gaactgacat tttatcgtca gtttcggctt ttttatgctt tatttcttct
    25921 tcggtgcgat tcccttgatc aggacttctg tccattctgc tgtatatgga agcagttttg
    25981 cgtatatctc cggcttagaa attccttcta ccattgcttg aaaatagagg atcaagaact
    26041 catccgaata tttcaaatcc acttttcctt ctttccgccc tcgatggaaa agatcaagca
    26101 tgatactgaa actttcttgc gtatacgcat ccatcgcgtc agaaaattct tttttttctt
    26161 tttttgtata gtatgtcatc aaatcgatat aaaattgttt gttcactcga ttgagataac
    26221 ggattttgtt ttcactcatg gcaatcagtg tttcttcaaa tggaagattt tccgcaatca
    26281 acgctttcgc ttcttgccct aaatcattca taaatgcaaa aaatacttca taaatcagcc
    26341 cttccttgct gccaaaatat ttaaaaatcg tcgctttact tacctgagcg ttctcagcta
    26401 ccttatccat tgtcactcca gcggttccta tgtctgtgtt catcaagtca aaagctgctt
    26461 gtaaaatctc tttctttttc tcttgtgctc tcttttcaaa accgttcatt tgtagagcct
    26521 cccgtaattt taaactttta taatatatat agttcaaatt tattctgagg tttattataa
    26581 ctatctattg agaaagtatc aagctagcaa ttccttgttt atgaattcat tgacagaaat
    26641 ttataaaaag aatattatgt actaaaataa taaaaaaagt tttataaaaa ggtataaaac
    26701 ctttttatta aactatttaa tcttgtttag tatatatttt tagaaaaagg agtggggttt
    26761 ttatggcaga aatcgtcaaa gtcacacatt tgaaaaagag ctttggtcgt ttcgaagctt
    26821 taaaagatgt ctctttcacc gtacattcag gtgaagtcgt tggatttatc ggaccaaatg
    26881 gttctggaaa atccacgacg attcggacac ttttagggat tataaaaaaa gacggcggaa
    26941 cggcaacgat ttttgggcaa gatgtatggg aagatagttt atctatccat gaacgtcttt
    27001 cttatgttcc aggcgatatc tctttgtggg gaaatttgac tggaggagcg atcatcgatc
    27061 tcttcatgaa gcttcatgga aaagggagtg ctcaaaaaaa agatgaactg attcaacgtt
    27121 tctctcttga tcctaagaaa aaagcaaaaa actattcaaa aggaaatcgc caaaaagtgg
    27181 gcttgattgc tgctttggct gttgattcgg atctctattt atttgatgag cctacttctg
    27241 gtttagatcc tttgatggaa acgattttcc aagaagaagt tgaaaaattg aaagaacagg
    27301 gcaaatccat cctactttct tctcatattc tcagtgaagt cgagcgacta gcggataaag
    27361 ttgtgatcat acgcgaagga acactcgatg aagaaggaac actcgatgaa ttgcgtcatt
    27421 tgactcgttc gaccatcact atagaaacag aagcagagaa tagtcactta gcacaattga
    27481 acggtgtcca tgactttgtg caaaaaggtc acctcgctca atttgctgct gataacgaag
    27541 ctttcgatgt gattttagct gaagcgtcca aattaggtgt gaaaaaattt gaatctattc
    27601 caccgactct tgaggattta ttcatgagac attatgaagg atgaggagga agcgaaatga
    27661 ctgataaatt ttcacgctgg tccacccttt tttctcaaaa ccttagccgt gactggaaaa
    27721 agatcctgat atggctagtc ggtgtcactg ctttttctgg tggttttgtc cctgcgtttg
    27781 aagaattgac ttccggacaa ggattagctg gattatacga aaccttgcaa aacccggcaa
    27841 tgattgcaat ggtcggacca actccagctt cgaatgctgc tgagtatact ttaggagcga
    27901 tgtatgcaaa tgaaatgttg cttttttgca gtttgtttgc tgctgtgatc tctgttttac
    27961 acgtggtgag ccaaacgaga aaaaaagaag aacttggtct gattgaactt attcgttcct
    28021 ttcgagtcgg acgtcaagca aactctttag ctgtcatcgc tgaaagtatt ctgatcaatt
    28081 tgcttttagc aatatcgatc agttgtacga tgattttttt ccaagcggat tcgatcactg
    28141 cagaaggtgc ttggcttttt gggctatctg taggtagtat ggggattttg gggagtgccg
    28201 ttgcactgtt tgctgcacaa ctgatgccaa gttcagccag ttcgaatggt ctgtctttag
    28261 cgtttttagg tggactttac cttctacgag caataacaga tgtagctgat tcctcccttt
    28321 cgatgtggaa tcctttaggc tggtcttatt tgacctatcc atttacaact aacaactgga
    28381 ttcctttgct ttatttgttt ttgttcagtc taatcttgat aatcagttca tttgttttag
    28441 aggaacatcg agatttgaac accggctata tccccgaacg tgaaggaaaa ccgtatgcta
    28501 aacgttctct tttatccttg cgtggtttat tattctatct aaataaaggg atgacaatca
    28561 gttggcttat cacttttggt ttgatggggg cggcatacgg ctctatctac gggaatatgc
    28621 aacagttttt agaaagtaac gacttaatga aacagatgtt tatccaatct ggcgtctcaa
    28681 ttgaaaaaaa ctttacaagc acgatcatgg tcgtcttgat ttgtctagct gctattttac
    28741 caattgctag catcaatcgt ttatttacag aagaaaccca cggacgtatg aatcagctgt
    28801 tcgcaacaaa aatttctagg aaccaacttt attggaccaa tatgttacta gctattctat
    28861 ttgctatatt ggcaatcctg attagttctg gtgcactagg gctttctgct ttggcttcga
    28921 tgaaggatgc gaaagacatg gatctattga tgtttcttaa agccgggttc aatttcctgc
    28981 ctgccgtttt agtgtttatc ggaattagtg gctttctatt cggatggctt cctcgaatcg
    29041 gtaaacttgc ttatatctac ttagcttact cctttgcact caattacttt ggcggaattt
    29101 tggatttacc agaatggttt tccaaaacag ctgtccctag ctgggttcca cggatgccaa
    29161 acgattcttt tgatctttcc gtgttcctta cgttatcatg tatcagcctt gcactgttcg
    29221 tccttggttc tattggttat aggcgaagag acttactaga aggataataa aaaagcatgt
    29281 acaatttcat gctagcctcc aaatctgggt caaaaatcca acatttggag gtcatttttt
    29341 tatttacaag tcttctaact gctctttatc aatgatccag acttctcgat tctttctttt
    29401 tacataacca ttctcctcta ataatttaaa ttttctagat aaagtttcgg gggtcgtacc
    29461 gataaatgca gcaagttctt tcattttcat tggcaggaaa aagtgatcct tccctgtcgc
    29521 tttagctaag tcaagcagat agacagcgac tcgttcttct actttttcca tcatcaaaaa
    29581 agttgtctgc tgctgtactt ttgttaattt ctcaacgttg attgctaaaa gtttcagact
    29641 aagggcggga taatgcagta agagttccga gaaatctttt tgtctcaata tgcaaatttc
    29701 cgttttttct agtgcttcgc caaataaaga ctcatttgga acgcctagca actggctctc
    29761 tccctcatat ccgcccggct ctattactcg taaaagctgt tcctttccgc tagcagataa
    29821 ttgatacact ttcatactgc cggaggccac gatcactaat tgaggttctc cattcggcgc
    29881 aagaatctgt tctccttttt ccacatagtg atgtttgaca agtgcgtgta ctttttcttg
    29941 atcttgctgt actaagtgat tgaacaaagg aacaaatgaa acacataaat gatcatgact
    30001 cataatctct cctccttcta aacagctatt tctaataaag aaacataact tcccttattc
    30061 caactgataa ttttctttta tcatagcata aacgtcaagc gaaccagata ccagcaaata
    30121 gagtggattt ctttttgtcc cttgctttat tttccttctt ttgagacctt aagtaattga
    30181 ttcctatcaa ttttttaaat atttactttt tgaataatca aaaacaaacc ttcactcgca
    30241 agccgacagt aaggtttgtt tttcgcattg cttatttcgt gttgtctatt gaaatttttc
    30301 cgcacctagc ttttgatata gtggtgctag ttcttgtaag gtttcagcgg ttatttgctc
    30361 aacgtgttcg atttcttgcg gatagaagaa tagtttaccc atttgaaagg ttcggtctct
    30421 catcgctttt ttcaactctt cttgtttctt tgtatcggac aaatagtcag acaaagctaa
    30481 gtggtcgtca agttcatgtt ctggttgcgg ccatatgtaa taatccttga tatcgactgt
    30541 tttgctccac tctttcagta tcgcaagcaa ctggttatac gctgcaatgc taccatatcg
    30601 ttcttcgctt ttataatgtt ggtacatcaa atagatttgg tattgttttt gattcaacaa
    30661 aactgctaga caggcattct cgtcttgacg agattcgctt cggtacgcgc tccaaaaatg
    30721 actgcgtaaa ttccagccat tcgtccagct ttcgatttta ggtttgctca tgccgtacat
    30781 atcaggcaaa agtgcagctg tctggagctg aatctctttc catttttgcc agtgttcttt
    30841 atattctttc ttgatttgtt caatcttatc tgttggatgg ctctctttga gctgtttgaa
    30901 tgcgtagatt ggtcgatcaa acaactgata atctgatttt ccaagttcca ttgtttcgcc
    30961 tctttccgtt atcttttgta ttctacctga attttgcgat atggacaaat agaggttgtg
    31021 aaaaagctgt tctgcatcaa gtcataagaa cagccaaaca aaaaactgcg atgagcatca
    31081 ccgcagtttt attgaactta aggttgattg atcacatcta aaagcgttga aaataaaatg
    31141 gcactagaag cagctcctgg gtcgatatgt ccgattgcac gctctcctag ataggaagct
    31201 cgtccttttt tagctaccaa gactttggtg tgttcttttg cctggtcaat gatttctttt
    31261 gttaaattcc ctgccttcaa tgcctctgtg actggcagcc aaacatctaa catcgtttta
    31321 tcgtcagctt ctgcctttcc tcggctttga atacccgctg ttccctgctc gatcacttcg
    31381 cctaattttt cttgagaatc aatagaatcg acctcttttg tcgctttcat catgttcatg
    31441 aatgcagatc cgtataacgg accagaagcc ccaccgactt tcgatatcat cgccatagag
    31501 aatactttga atgtatcgct gattgtttca ggatgatcgg cttgaaaagc ttcttcataa
    31561 gctgaaaccc ctcttcccat gttatttcca tggtctccat cgccaatcgg ggtatctaga
    31621 tcactgagat attgtttgtt ctgattgatt gcctctgcaa attgcgtgag ccattcttgg
    31681 atttcttgaa cggttagttt catattatca cccttttatc ttgagatttt ttaccatgaa
    31741 atcgtctgta cattgctttc taaagaatct ttccattgtg tctccgtcaa gtcgatcagt
    31801 gttagagaaa gaccttgcat atctagtgag gtcataaaat taccgacttt tcggaaaact
    31861 acattgacgc ctctttcttc caacagagct aaaacatcat tcatgaacac gaactgttcc
    31921 atcaaaggcg tcccgcccat tccgttgact agtacacctg cttcttttgg taaattcgag
    31981 taatcatcta aaatcttagt aacaagttcc tttgccagta ctttagaagg ctgcatcttt
    32041 tctcgacgat agcctggctc accgtggata ccaacaccat actcgatctc atcttctcct
    32101 agttcgaatc ctggtttccc tacttctggt acagttgctg ctcgaagcgc tagaccgatc
    32161 gtcttagttg cctgtacgac cttttctccc agttctttca actcagctag ggaagcaccg
    32221 tttcttgctg catcgcccac gattttgtgt acaaggacag tacctgcaac tccgcgtttt
    32281 ccagcagtat acgtactatt ttcaacggcg atatcatcat ctacgatcac actttctact
    32341 tcaatatcgt ccatagcagc taattccttt gccatatcga agttcaatgc atcccctgta
    32401 taattcttaa cgatcagcaa aactcctttt ccactatcgg cttccttaat agccgtctga
    32461 atctgatctg gagttggaga agtaaacaca tcaccaagca ccgctgcact taacatccct
    32521 tcccctacaa acccggcatg ggatggttca tgtccgcttc ctccaccaga aaccaaacca
    32581 acttgttccg ctttctgatt cttggctaca acacgggaag attctacacg atgaacaagt
    32641 tctggatagc tttttactaa tccttccagc atttcttcga caatattgct tggatcattc
    32701 atgatttttt tcaatttatt cccatccttt ctttccggca ttttgtgctt ctgttaagat
    32761 ttgctgagta tcatctgtta taccggcagt gatggctgct gcaaaagctc cttccactaa
    32821 aggcgcatcc accagatgat aacgttgctg ctgctcttct tccaacatgt cttttgccag
    32881 ttccgagttc aataccgcgc taccgatatc cgcaaaaaca aaataactag ctgcatcgct
    32941 tgattcattg actgcttcta cgattttcat cgggtctgat ccgatctcgc catttattcc
    33001 gccgagagaa aaaatttgca cctcttcgga tttttgcatc tgctcaatca tttctttaat
    33061 accatctgtt actttttgac tatgagaaat aagcaaaata ctttttttca caagaatctt
    33121 cctttctttt acatagttgc taacgattgg tttcgctttc attaatgaac aattcaagta
    33181 tataataaat ttctaatttt gggaaaatat gtgtagtgct tcttgaagtt tgttatactt
    33241 taattaaaag agaggagtga tcgaatgatt acaacaacaa cgaacagtgt agagggaaaa
    33301 gccgtagtag cttataaagg gatcgttttt ggtgaggtca ttactgggat ccatgcattt
    33361 aaagacttgg aggcggggtt gcgaaatatc tttggcggcc gctcaaaaag ctatgaaaac
    33421 gaactaatgg gtgcaagaga agaagcactt gccgaaatgg ccgaacgtgc aaaagcatta
    33481 ggagctgatg cgatcattgg cgtaaaaatg gactatgaag tattaggcag cgacaatggc
    33541 atgctgatgg tcacatgtag tggaacagct gtctccacga gataagtagg ggacatctgt
    33601 tttaataact aaagagagat gggacatgta gtggcactca agaattagat ttttcagtct
    33661 aacttcgagg tactctacct tcccatcctc tcttttttat ttctttttgc ggatgattcc
    33721 gtaagctgct gcgactaaca cacccgcccc tgctaaggaa taactgacag aagctgtttt
    33781 ttcatttgtt tttggcaaag tctgacttgt tgatttggat ggctctgtcg tttgctgaac
    33841 tgtttctgtc gtgcttccag aggtcactga tttttctcct gccgaatgca aaatatcttt
    33901 tattcgttgg aaactagctg ctaagtcagc tttttttgct tcaaaatcat tagcaactgt
    33961 ttgtgcttcg ctgatctttc cgtggattgc ttgactggcc gctgtgatat ccgcttgagt
    34021 ttgacttagc tttccagaag ctgtttgagc aacctgattt aattgctgat tgaattcttt
    34081 tgcttgttgg atcttcccgt caagatctgt ttggacagct tccgcttttg ctttcgcttc
    34141 ggcaagcttt ttctcaagtt gtgcacggtc atttcccact ttatttttaa gatcagctaa
    34201 atcttgatcg attgctgctt ggtcttcttt caatttgttt tttgcagctt ctaatgcttc
    34261 ttcgagttct tttcttttat tttccaagtc ttgcaaatga tcgatttggt cagaagaggt
    34321 agaactattt attgatgtat cttctgaaga tgaaatcgtt tctcctgaat tatctgtcgg
    34381 tacattggaa gtcatttctg tttccgaggc accgttttca gcaccagaag agcttatggt
    34441 tgttgaaggt tctgtttgag caggttcaga agtttccgca aaagctgtct gtcccaataa
    34501 gaaaatactg gaaacagcaa ttggccagat taacggcttc attctttttt tcatcacttt
    34561 tcccatcctt actacttttt aactaatttc ttattataag caaaaatgtt tggaagaacc
    34621 ataaacacaa caggctgttt gtctaaaaaa cggtgcatct tttatttttt tgtacgttcc
    34681 gggcttttcc atgtcccgct tccataacct aaaatcgttt tgactgctgg aatgaaagtc
    34741 gtcacgatcg ttatcgcgtt cactatccag aacaaaagca tatatagtgg tgcgaaaaga
    34801 aggtatttca attttcttcg tcgatcatct acaatcagcg aagctagcaa ctggaaaaat
    34861 cctgcgacca tttcaaagca gatgaacaca aaactgaatg taaaagtaat ataaatctgt
    34921 tcgtagtttc cttgatatac ataatgcccg attaatccag caaaaagaac tacggaaata
    34981 caaaagaata ttgaccagac aatactcaat gtttgatcaa tgaagatgat cgttcttcca
    35041 atatgtttaa aaggatggag catcactttt ttgaaattcg tcagccagac ttctgttcca
    35101 ccttttgccc aacgttttct gtgtcgatat agcatcttca acgtcacagg tacttccatg
    35161 aaaaagataa tctcaggagc aaaaacagat aaccagtcat ttaactgatg atcccaagca
    35221 atactgatgt cttctgtcgc tcgatcttgt ctgaatccgc ccacatcgat caaggcttct
    35281 tttcgataca tcgtatttgc tccactgtac gcataaagac caccgaaaac agctgactgt
    35341 gttcgtttaa tgatgcccac gatacttgag aattcaaccg tttgagattt tgcaatcaat
    35401 ttggtacgat tttggacatc catatttgca gtgaccgcag caatatgtct tgcaccaggg
    35461 cgaatgaaat aattcacata cctaatcagt gcatctggct ccggtaccgt gtctgcatca
    35521 ttgcttaaaa tcaatttccc ttttgcaaag gcaagtccga tattaaacgc gtgggctttt
    35581 cctttatttt tttcgatccg aaccacacga agattagcgt attttttcat cagtctagct
    35641 aatatttctg gtgtttggtc cgttgaacca tcgtctgtca ctaatacctc atagttgtga
    35701 taattcaatt tcgtcatcaa atactcgatt gtatattcga tcacaatttc ttcattatgg
    35761 gctggcacca tgatcgtgat gaacggttcg acactcaagg gaacatctac ccattctttt
    35821 tgcttatgtt tgtataaaaa cacataacac cagacaccaa taaaccatac aaatccgcct
    35881 aaaatcggat aagaaacgag aaaaaaatac ataatagaca aacaagtatc taagaataaa
    35941 ttacctgtat gggtgattga gatcatttca gttccacccc attttcttta tacaaatctg
    36001 caatgaatgt cgtatctaga tttttctctt cggagacaga ataaaaacgg accgtttctc
    36061 tctcttcttt tgttccaaaa cgttccgtat acacttcttc aagtaattct tgtctttttt
    36121 tcaatttttc atcttcatat tcaaaagatt tatttacttt tttgtataga tttcgattgt
    36181 tccacctagt caatacaaat gaggtaatca ggaaactgaa aaaaatcaat acaaaaaagc
    36241 cgattaagaa atacagcatt ttcttttctg ataaaaaagc gtacaaggaa aaatccttgg
    36301 ctctttctgg tctcgttaat gggaaaaaga cccatataaa aggaagaaca acgatcatcc
    36361 atcctaaaag agccactaac gtttgccaaa tctttaacca gtaattacct tttgaaaaat
    36421 acttatcttt caccaaaatt gatgcaactt cttctcttgt tacttttttc atatcctcac
    36481 ctcacgtttt tttgttacga cgtaggagtt taccatacat ttcatttctt ttcacataaa
    36541 gtgttcctaa atttttccta agaaaaagaa caaaacattt ctcatcagca aatgaaaaat
    36601 attttgttct ttttatcagt tgttcttttt attttttatc tcttaattat gttgctcttt
    36661 ccaatacgac aatgcttttc attcctctag atatcgccgt gtacatttgt ctgcgtcttc
    36721 tttgctcatc tccatcgttt tcaaatggat ataagattac atgatcaaat tccagtcctt
    36781 ttgctagact caaaggaatg atttggcagt tttctaatcc atatgaattt tttttaatcg
    36841 attcttgtag cgtttgggtt tcctcttctg tttgggtgat aactgccgct ttttctcctt
    36901 ttagagaaac caaaatctca gctagtattt tcaacaattc ttcagaggat cgaaaagagc
    36961 ggtattcggg ttcttttcct tgcggtcgga tcgatacgat gtcgatcttc tcttgatcca
    37021 cagcataggt tttgaaaagc tctgtgattg ctccgctaga acggtaacta tttctaagat
    37081 cataccgatg gatcggcaga tggtagtcgt cgaaacaacg cataatatca gcaaaagtag
    37141 tggaagaatt aaagattgcc tgattctcgt cacctactaa agtaaagtga gtttttggaa
    37201 ataattcgat caatagacct aattgtgcca gggtataatc ttgtacttca tcaatcaata
    37261 gatagcgaaa tgctggtaca tttacctttt caacaagtaa atgacgaata gctaatataa
    37321 tgactgcttc atcaacagta cgtgtgggtt gccaagcata agctgagcca tatcgttttt
    37381 cataaattct ttcaaacaac tgatgctcat ccacccatgc catttcttcg atttgtctgg
    37441 ttatttttcg atattttttt tgtaaaagtt tccttgcata agctacaata ctttgttccg
    37501 aatcatcaga aatcaattta ccgaataatt ccaactgcct atcttctgtc aacgagagta
    37561 cctgattctg cacagcagga ctttttgctt gtttcaaaag atgattcttc cattcgctca
    37621 tcagtgcctt tttcgttgct tgaagcctat cgatcaattt aggatgagca ggaactttct
    37681 catatatttt ttcgatcgtt tttttagaaa ggactgtttt tccattttta gtaagtccac
    37741 ggataaaatt cggatgatct aaaaacaaag gatctgattg ttttagatta tcgataaact
    37801 ttttgctacg caaacgttct gtctgctccg atacattttc tcccgtgata cgtttgaaat
    37861 aagcctcttc accttctatt tcctctgctg aaagctgtga aaccagctgt atgatggtta
    37921 gattcagtgg atttctttca cctaatgatg gtaggacatt cgaaatatag tcgataaacc
    37981 gatgattagg tgatagaatc agcaagtcat cggatgtcat cgtatctcga tataaataga
    38041 gcagatacgc aatacgctgc atgatagcag aggttttacc acttcctgct acgccattta
    38101 ccaagatatt ttgacttttc acatcccgaa tgattgtgtt ttgttccgat tggatcgtag
    38161 cagtgatagc cttcatttca ttggtctcat cttggcctaa gacttctaat aatacgtcat
    38221 cttgaatagc tacagacgta tcaaaaaact tgaccaaacg atctctttcc aaaagaaatt
    38281 gtcgtctttc tttaataacc gtatcgattt tattttgacg aaccgtataa gaagatggac
    38341 caatcatgtt attgtaaaaa agttcggcaa ttggtgaacg ccaatcataa acaagatttt
    38401 catctgcatc atctgtgaaa tttgctgtac cgatataaaa ggattctttt ggctcattat
    38461 ccagaaagtc tacaacgact tttccaaagt agggactttt caataaacgt tcgatctttg
    38521 ctagctgatt ttctgcgttt ttctgtttga tattcatctg atcgatttct ctatttttca
    38581 tttcaatcat cgaaaaagta tccaggttat ctaagtaact gtcaaaattc aatcgaagct
    38641 cgccagccat ttctttcaac gactggtttc cttctatttt tgccgtatcc atcgattccc
    38701 gcagttcgtt ttttttatca attagctttt gatacacgtt cttcagatat gcttcttcta
    38761 actgtttttg tgtgttgacc atacacattc tcctcttttt ttaaagtggt ggaaccgatt
    38821 agtttacctc ttttaagagt cgaatgcaag ctttttaacg agtatcattt gttaggatat
    38881 atcagttctt caggtcggac agtttgatat aaagaaaatg caccatcaag gttttttacg
    38941 tggtagccag actgcttcaa gattctttcc gctagatagc tacgtaatcc gctatgacag
    39001 ctgacgatat attcttgttg gctgtctaat tcatttaatc ggtcccgaag ttcattcaaa
    39061 gggatatgtt tggcttcctt gaatttgccc ttttccaatt cttctgctgt tcgcacatct
    39121 aataaaattt ttccttttgc tagttctgtc ggcaattcat gccattgtac ggtttcacta
    39181 agcccttctg caatgttcat tgctgcatat cctagcatgt ttactggatc tttggctgag
    39241 ccaaatggcg gtgcatacgt caattctaat tccggtaaat cgaagatcgt caaatgccct
    39301 ttgattgctg ttgctaaaat atcgatccgt ttatccacac cttttgcccc aacaccttgt
    39361 gcaccataaa tctcgccagt ctctggatgg aagatcaact tcagtaaaat atctgttgct
    39421 tctggataat agcttgcatg atcttttcct gatacatgaa tgacttcaaa agacagttcg
    39481 ttttctttgg ctgttctttc acttaaaccg gtggatgcgg cagtcattcc aaacgttcgt
    39541 ataattgctg ttccaatacc gccttgattt cttcgagaaa ttccggaaat cgtgtccgca
    39601 acttgtctac cttgacgatt ggctggtgaa gcaagagaaa taagtgcatc ttttccagtg
    39661 atttgctgtt ttacaacgat agcatccccc accgcataaa tatcaggaat attcgtttga
    39721 taacgttcgt ctactaggat acccccgcgt atgcctaatt cgattccagc ggtcactgct
    39781 agctggttat caggacgaac accaatggat aaaataacta aatcagcagg gatggtacgc
    39841 ccatcatcca gtcgcaatcg tttcccgtgg tcttcaaatc cagcgacagc atgagaagta
    39901 atcacttcta ctccttgatg agacaattct ttttctataa aagctgccat ttcttcatcc
    39961 agtgttggaa gaatatgtgg tgcttgttcg atcaccatga cttctaaacc tcttcttttt
    40021 aggttttctg ccatttccaa tccgatgaat cctgcaccaa cgatcacggc acgctttggc
    40081 tgtttttcta atgcatgcat cactttatcg atatctggta catttctaat agaaaaaaca
    40141 ttgtcggctt ctgttatccc tggaatcgat ggaacaactg gttttgcacc aggagataaa
    40201 accaatgcat cgtactgttc aatgtgtttt tgaccctcat gtacgacttc taccgttttg
    40261 ttttcgggaa agatggctgt cacttcatga tttggacgca catctaaaca aaaacgagcg
    40321 gataatgatt ctggcgtttg gacaagaaga ttttcccgtt cactgatttc tcccgaaaga
    40381 taataaggca agccgcaatt tgcaaaagaa acatacggtt ctttttcaaa aacaacgatt
    40441 tctgcatctt ccattaatcg gcgaagccgt gtagcagcag acattccacc tgctacacct
    40501 ccgacaataa cgattttcat cttatttccc tcctactgtt cgatcaaacc attgattcat
    40561 gccaccacgt acattcacta catcataacc agatttcttt aattctttag ctgcttgttt
    40621 actcctcatc cctgattgac aaatcacata gacggtcttt tctttgtctc catcatatct
    40681 gtttatactt tgtaatggaa catttttagc tccttttata tgcccgcccc ggtattctgc
    40741 aggtgttcta acatcaagta acgctggatt ttccaaaagc ttttccttta attctgggac
    40801 tgttatcgat tttattgatt gaaatagcaa attcattttc tgcacctcat ttacattttt
    40861 ataaatacct catggggtat attaaacagg agctttatta atatgtcaac cagaatgact
    40921 cttcattttt ttcactactt tttatatttg cataaaatac cgataagggg tattatctaa
    40981 ttataaaaat agaggagaat gtgttatgga gattgataat aaaaatatcc tgaaccgttt
    41041 gaaacgtaca gagggacaaa ttcgtggtat ccaaaaaatg atcgaagacg aaaaagaatg
    41101 tatggatgtc atcactcaat taagcgctgt tcgttctagt attgatcgcg taatgggcat
    41161 gatcgttgca gataatctga aaaattgctt tgagaaacct gatagtaatc cagaagaaca
    41221 agcggctaaa ctagaacaag cgatcaagat gattattaaa aagtaaagga atgatttcaa
    41281 tgaaagtcgt tttccatatt gatgaattag aaaaatggtc agaaacaggg aaaaacgtaa
    41341 aaaacctgat aaaagcttct ccagaaacga cgattgtcgt atctgtaaat ggcatcgcga
    41401 ttaccggtta tctagactct gccaatgcag aattcttaga tttgcaagga gtcgtttttc
    41461 acgcttgcgc caatgctatg cgtgctaatc atatttcaga aagttcttta cctgaacaag
    41521 taatcgttgt accagcaggt gtccttgatt tagttgaact gcaatcccaa ggttatgctt
    41581 atatcaagcc ttagtcagta gaggttgcga cagaagtgat cagcttcaag aaatttcggc
    41641 ttatttttcg aagaagctac ttctggaaaa ccgtgaatca aaggttgtga aaacgctgtc
    41701 ctgcatcaag taataagaac agccaaacaa aaatagcttc tcatattttt cgtttggttg
    41761 ggcttattac cgcagatgca agcttttgaa caccgtttaa ggaagaggtt gtgaaatcag
    41821 cggtttgacc taagtattag agaaaaaaac gggaaaatag ctcctcatat tttgccgttt
    41881 tttgagctaa taccgaaggt cagctgattg aacaccgttt aaggaagaga ttgtgaaaaa
    41941 gtcgcttagt ttcgagtatt aagaaaaatt ttgtaaaaat ggatttctac atttttgcat
    42001 aaatttggct taataccgag aaactggctt ttgaataccg tttaaggaag aggttgtaaa
    42061 atcagcggtt tgacctgagt attagagaaa caaacggaaa aatagctgct catattttgc
    42121 cgttttttga gctaataccg aaggtcagct gattgaacac cgtttaccaa gaggttgtga
    42181 gcctaccatt taactccgaa tcacaagaaa taatttcaaa aacaacttct cctgtttttg
    42241 gttcggttgg cttattatcg agaagtagct actgggagtc tatttatcaa aaaaaggaat
    42301 gcgacatagg tcacacccct tttttatttt ctttgaaaca tctttcggta ctcgacagca
    42361 tacaagacaa aagattgtaa aagaccgtaa gtgatgacgg caaaaatgac tctcacccac
    42421 agcgttggta attctgggaa aagcagcaaa aggatcatgc caacatagat gacagcagtc
    42481 gctactttgc cataccactt cgctccactt aatttgatat ttttagatag cccgattaat
    42541 ccagctacaa acataaagcc ttcttttatc aagaatagac caaacaacag ccaaagccac
    42601 ggtcgatacc atgccataga caaaatcaga aaaagttgtg tcaatttatc tgcaaacgga
    42661 tcaagcacct tccctaagtc tgttacctga ttatatctcc gagcaatgac cccgtctaga
    42721 taatcagaca aacctgagac aacaatgacc gctcctgcta tataaaatga ctgtctcagc
    42781 acaaaataaa gataaatcgg cagcaaaaaa atacggaata tcgataaaag attcggaatc
    42841 gtttgtattt ctttacgcca gtctgtgctt aatttcattt tatcgcccta cctcctcagc
    42901 actcttttct ttttatttta gcttacacgg ggaataaaac caatgatttc actgttttta
    42961 tttttcttta cagacactga tattatgagc taatttgaga taatcacttg ctgttttcat
    43021 cgtttactct tctttcttcc tgtcgtttgc gcatttcttt tactagtact ttatgagctt
    43081 tttttgatcc tcgctctagg tcacgctgcc gtttacgtgt tttataatcg ataaacagac
    43141 tgtctaaatc gtaacctgtc gggtacagat cttctgctga acgcaccaga cgaacacgct
    43201 gacgaggcac gtggattatt tttttgtcta aatatacatc aatcgtatct tcacctatat
    43261 cttcataaac taacgcttct ttttggtatt cattgacaaa tatccgatca ccttttgcaa
    43321 agagctgacg ttctttttta ttctccttcc tatttgtaac tgctgtctta ggaagaaatt
    43381 cttttttctg tgtccgatag gctttttccg ccaagtaacg ctttgcttga tggatcaatt
    43441 tcatcgacat atccatttta tgagcaatcc acaaagcttg gctttctcct gtttcttcca
    43501 acccgcaact gatatttagg acgaagtgct tcccgatcga aagccatagc agccggcaca
    43561 aaatcttcat gatctccggc gaatttcttg atttctccat aatgggtcgt ggcaatgatc
    43621 aatgcccctt gctcatacat agattccatg attgcgatcg ctagtgcagc cccttcattt
    43681 ggctctgttc cactgccaat ctcatctaaa agtaccaacg tattcctttt tatctttttc
    43741 aaaatagcag cgatgttttg catatgacca gaaaatgtac tcaacgcatt ttctaaattt
    43801 tggtggtcac cgacatcgac gaaaatctca tcaaagacag caagctctgt cccttctttt
    43861 gccggaactt gcataccgaa catcgccatc aaagtcaata aaccgactgt cttcaacacg
    43921 actgttttgc ctccggcatt tgctccggtg ataatcaagc ctcgatagtc tttaccgatt
    43981 tcaacatcca atggtaccgc atgctcaggt aaaaatggat gtctgccttg cttgataatg
    44041 atatgttccg atttattgat tctaggtgtg cttccattga tttctcggct aaattttgcc
    44101 cgagcaaaga tgatatctaa caccgtgatc gtttcgatca ataaatcgat cacttcttcg
    44161 ttttctgcga tagcaccagt caatgccgcc aggacttgat attcttcact gatttcttca
    44221 gcttttaaca actgatagtg ttcattcaat ttagaaatca cagttggttc aataaaaacc
    44281 gtcgttcttt tatttgattc atcgataatc gttccatcta ttttattttt atagctggct
    44341 ttgataggaa tcgtatagta ttcgcctttt tgaacaatca ttgcttcttg gatcatttct
    44401 ttgtttttcg gatgacgcaa gaatttcagt aattttgact ggatttcttt ttcgattagt
    44461 tgtaattgtt tgcgtacttt acgcaaatta cgtgacgcgt cgtcactgac tttattattt
    44521 tttattttct ggtcaatcaa ctcttctaca tttatcaaat caggaagatg tttgctataa
    44581 gcaaacaaca agggtgtctg gtattgattc ttatcaaaaa actttgtgat catccgactg
    44641 cttctaagaa aatccgcata ttcgatcaaa tcggttggct gcagaatcaa cccttttttg
    44701 acttgttctg tcagtgcatc gatcctcggc aaccccataa atggaacatg ctgactgctt
    44761 tctaagatca agcgtgcttc tcttgtttct tcttgacgat ccaagacagt ttgtaggttt
    44821 gtcgagaccg tcatatcgct gattcgtttt ttgctatagt ttccaattgc tcttgcttgg
    44881 atttcctttt tgatccgatc aaattgtaat tgactaatca tttcgttgtc catattctct
    44941 ccttttcttg aagagatacc tgtcccaaaa taaataaggg cctagagata aataaaagga
    45001 tagaacacag cttaaaaaag tcatgtccta tccttattag aatacaaaga tattgttttc
    45061 ctgacaggta ccgtttcata agcacaccaa ataaactttg tttattggct attcgactta
    45121 ctgattagat accagctaca ctcacaaaac ataccccatt cttctaggtc ttatttattt
    45181 tccacttaac tatagcaaga cacattttgg ttgtcaaact ttagtatgtt ttatagattt
    45241 acaccattaa tgaatagaca cctaccgcga taattgctcc gatcattgga cctgcgattg
    45301 gtacccatga atatgcccaa tctgaagttc ctttattagc tattggcaat accgcatgtg
    45361 ctaatcgagg accaaagtcc cgagcagggt tgattgcata tcctgttggc cctcctaatg
    45421 aaagaccgat ggctaagatc aatccaccta cagcgaatac gttcgttcca ggtgcaaatt
    45481 cgttttgtcc aaaagctagc aacccaagaa ctaatacaaa tgtaccaatt aattctgtga
    45541 tcacatttgc tggataattc cgtatagcag gacctgttgc aaacgttcct aaaatcgcgc
    45601 tttcatcttt cgttgcattc caatgtggca aataagaaag ccaaacaaga atggcccctg
    45661 caaaagctcc taaaacttgc gcaatgatga aaggaacgac aagattccaa ctaattgccc
    45721 ctttcatcgc catagctaga gagactgcag gattcaaatg agctgggccc atgaatccag
    45781 aaatatagac agccattgtt acagcgagtc cccaaccaaa tgcgatgaca atccagccag
    45841 aagcctgtgc tttacttttg tttaaattca cagccgcaca cacaccatct ccaagcaaaa
    45901 ctaggatcag tgtcccaata aacttcccca tgatttgagt catatcactg ttcatttatt
    45961 tctccccctt tagttcccgc agatctgatt ctgcaatcaa tgcttctaaa cgtttagtct
    46021 gttgcgcctt ctcctcttct gtccattcaa aatatccagc aattgcatcg atcacaggtt
    46081 gcttgatctc atcaagctga tctcgttcaa acaacagatg atttgtacga cgaatgagat
    46141 aatcgcctgg ggccaaaacc atttcttctt ctaaaccata acgtaaccga gctgactcag
    46201 cgagactcaa accaggataa ggtgccattt cttttgctaa ttcaaagata cgtcgggcat
    46261 tagtcccgta aaaatcagcg atataagtag catcttcttc ctctaaaccg gctgctactc
    46321 cttcttttgc taattctgtc actgtttctt ctaatttagt tggatcgaag tttccacctg
    46381 aaatctgata ttttttagag tcgatttctt tcgtctctat tccgtattct tcttttaata
    46441 attggcgtat caatcgcaaa gctccttctg ccatcttacg gtaatcggtg attttcccac
    46501 cagataaagt cagcaaacca tctggttctc tttctaaaga actacctctg gaaatcgtag
    46561 aaggtgcttt ttcatcacgg ctgttttcca aatggttcaa cacgtcttct acttcagcac
    46621 gagaaacttt gttttcctta tattcactta ctgtatcgac aactttattg aagctcttgt
    46681 ctgaaatcga tccattatct ccaccattgt aatcagaacc agaattacca atcaacagtg
    46741 gacgaagtcc tgcccagctt gcttcgatat cattcaatgt gatatttgct tctggatagc
    46801 gatgattgat cacatccaat agataatcta catcttcttg tgtgactttc ggatccgtaa
    46861 aatctccttg gtaatccgta tctgtcgtac caaagtaagt cttgttttct cttggaatag
    46921 caaaaaccat ccgcccatct tgctttcctg tatcgaagta tgtgggttgc ggtacaggca
    46981 gttttttcgc atctacaact aaatggatcc ctttagttgg acgcatttta ggagagactg
    47041 gacgcgtaaa attcaagttt cgtactttat ctacccaagg accactcgta ttgatcacta
    47101 attttgcttt gatttcgatc acttcatctg tcagcaggtc acgagctttg acgccaacga
    47161 tttgatcgcc atcatataaa aagccaaccg ctttcatttt acttactaga taagccccat
    47221 cttcggcagc ctttttgata ttatcaatca ctaaacgggc atcattgttg cggaaatcta
    47281 gatagacacc cgcgcctttt agcccttctt ttttcaaaaa cggttctctt tccaatactt
    47341 cttctggtgt cagcgtataa ttctcatatt tggttcctgt cacatttgcc agtttgtcat
    47401 aaaggtccat tgctactttg accgagaaca tattgaaggt tgttgctcct tcgccctcat
    47461 agattggcaa aagcattgga tctggttttg ggatgtgtgg ggcaatactt tgtacgactg
    47521 cacgttcacc aactgtgtca gctactactt ccacatcaaa tgtcttcaga taacgaatac
    47581 cgccatgaac aagtttggtc gagcgagagg aagtcccttc tgcaaaatcc tgcatttcga
    47641 tcaatcctgt tttgattcct gatgctgctg actggactgc cacaccggca ccagtgattc
    47701 cgccaccgat gatcaacaga tccaattctt cttgctgcat tttttgaatg ctatcttgtc
    47761 ttgtcttgtt tgaaaacata tggatttcct ccttattcaa atgcttgggt agcttttact
    47821 gcttttttcc aaccgttgta aagtttttct cggcgctctt cctccatttg aacttcaaat
    47881 agcttgccag cttcataaaa ttcgcggatc tcgtctgtat ctttccaata accgacagct
    47941 aatcctgcta aaaatgctgc ccctagcgcc gttgtttcca agttttctgc tcgttggatc
    48001 ggtacattca agatatctgt ttggaattgc atcagatatt cattgtttgc tgcaccgcca
    48061 tctactttca atacaggaat cttgattcca gtgtcatctt gcatcgtatc gatgatatct
    48121 ctcacttgat aagcaatcga ctgtaaagta gctttaatga tatcttcttt tgtcgtacca
    48181 cgtgtcaagc caaacatagc ccctcgtgct gcctgatccc aataaggagc acctagccca
    48241 acgaatgcag gaacaacata aacctcatct tcgcttgtag agcgtttcgc tgcgtcttct
    48301 gaatcgctag ctttttgcaa catttgaagt ccatctctca gccattgaat cgaagaacca
    48361 gccacaaaaa tacttccttc taaagcatag taaacctttc catttatgcc gtaaccaatt
    48421 gtcgtcaata aattattttt ggataattgc ggtttttcac cggtattcat gacaataaat
    48481 gaacctgtac cataagtatt cttgaccatg cctggttcga atgccatttg tccgaataat
    48541 gcggcttgct ggtctcctgc catccctgaa attggtgctt cgcttccata aaaatgataa
    48601 ccttgcgtat aaccataaac ttctgagtta gaagtgactt ttggtaacat cactcgagga
    48661 atatttagta aatctaaaat ctcctgatcc caatctagct gatggatatt gaacaacatc
    48721 gtccgactgg cattcgagta atcagtaaca tgtgcttgtc catcggtcag tttccatact
    48781 aaccaagaat cgatcgttcc aaacatcaat tcgccttttt cagctcgttc ttgcgcgcct
    48841 tctacatgat caagaatcca gcgtatcttc gttgctgaga aataggcatc gatcactaac
    48901 cctgtttttt cgtggaaaaa ttcttgatag ccttcatttt ttaagttatc tgcaattcca
    48961 gctgactgtc tggattgcca aacaactgca tgatagattg gacgtcctgt atctttttcc
    49021 catattactg ttgtttcacg ctggttcgtt atgccaatcc cagcaatctg atttggtttg
    49081 atccctgatt cgatgaacgc tccggcaata actgactgta cagaattcca gatttcattt
    49141 gcatcatgtt ccacccaact ttcttgcggg aaatattgcg tgaactcttt ttgagaactg
    49201 ccgatgtgtc ttcctttctt gtcaaagata attgctcgtg agctagttgt accttggtca
    49261 atcgccatga tatacgttga ttctgtcatt gtgattccct ccattatatg caaacgcttt
    49321 ctttaactac tcttatcata ctactgtttt aaaaaaagaa actgtcaaaa ttttattctt
    49381 tttttctttt tttgacagtt ttttattatg aagctatttt ttaatcaatt cttttctttt
    49441 ttcagcgtct ctattcttct tttcaatcga ataatgtcgt aaggtgacgc aaattctgac
    49501 agataatatt cacactgttt tttgtttctc tggcaaaatg tgatcaccaa atcatattct
    49561 ttaccttctt cataacttcc aatctcaata ccgccgattc ccctcagttc tctgatcaga
    49621 tattgttgaa aagcaatacg ataaatcggc agactttcta aatcgattcc aatcactact
    49681 ggttttgcaa tataaaaatc gatcatcaaa agaacattgg catactggat catcaggtaa
    49741 ctaagctcac tatcttcagc tcttttcctc ggcaattgct gcaccgctgt ttcctgtaat
    49801 ttcgccagta actgtgttaa ggaatgcccg agcattttct gctgctgttc caaaagccga
    49861 tcacgctcat agacttcgat ctttccaaca aagaaaaacc attcattgtt gatctgggaa
    49921 atttggtagc ctactgcctt ttcttctttg attttcaaac gacgaggacg ataatgccat
    49981 aacatcgttt cccgaatgta agtatctaaa acagcggttg gtaacttttt gctccgtgtc
    50041 aaatcatact gataaaatat ttcttcgtct actatcgaaa aagaaacaaa aaagctgtaa
    50101 aacatcattg tttcgtatac attcagttct gctgctgttc gactaagatg catcacgatg
    50161 attggatcga ttgcttgata aagccggtcc gactgataga gtaatttctt ttctttcaaa
    50221 gttgcgtacg tacttttttc attcaatagt ctttttttcg taatcccgag ccagcaagca
    50281 atctgtgctt ctgctgatgc cgtaaacgtt gtttctaata cacggtccaa tcctagaatg
    50341 aacggtcttt tttctggtgt attttgcaaa aaaagcggtc gctgatcttc cgggatatat
    50401 tggaatagtt cataataaaa atatcgtatc tgtagctctt ctccgtataa ttgaccgttt
    50461 ttgatttgta atccaaattc ctctaagagc tggttcaatt ctttgatctt tcgaaaaaca
    50521 gaagactcac tgatattaaa cgctgtcgct aatcgaacga tggatacttg ctgatgttct
    50581 aataaataga cgagcatctt aaacttcaag ctttcctgca ataaaaacaa tagaattttt
    50641 tccaaactta catcttcgtc caacacaagc agcgcctgat actcatttcg ctgtacttct
    50701 actttttttt ccatcattcg gccaatcaat tcaatatctt ccaaatattg atcaaacgag
    50761 gcttttgaca gttggacatg ctctctcaaa ccattgatag aggctgttcc cccttgcaga
    50821 acaaggtttc gcaaaatcag gatctgtaac tgctcttttc tttctaataa tgcttcaatc
    50881 ttcataggca gtattcgcca cctttgacca caccatatct ggcacacggt attctggctg
    50941 gaaaaatagc tcatgttctt ctaactgttc aaacgtccat ccttcttcta ctgcaattgt
    51001 cagttggtca agaaggtgga acatctcttt tttgctttgg agctgtgctc caagaatctt
    51061 tttttcagaa tcaaatagaa atttgagttt aactttgctt tgatttattg ctgtaagctt
    51121 gtagtctacg tatcctgttt caattttttg gggataaaaa atgctctctt cttctgtcaa
    51181 acctacgctt cctaagaaat agccaaacca ctgattgccg actggacgat aggttccctg
    51241 atcctttgtc tgtgagccac taattgtctt gctgacattt cgtgctgtac ggacagcgtt
    51301 atttactaga gaaacataca ttttttcatt tgttggacga aaagttactt ggatcgcatc
    51361 gccaatcgca taaacgtctt tttgagacgt ttgcaagtag tcatctaccc agatcgttcc
    51421 atcatcattc aatgttaatt gttcttccca catctgattg tcgggacgag aatgattagc
    51481 cagcaaaaca agatcatagt tctcctttct tttttccgtc tctacaatag cggtttcatt
    51541 ttcggtcaaa gacacaactt gttcttctaa aaaaagtgaa agcccttgat ttttcatttc
    51601 ctttactaac ggttctgtca tttcaggatc tagataacga aaaagaattg actttcggct
    51661 ttcgtaaaga tggatttgtt tttttcttga tgccaaccct tcagctattt cgattcctgc
    51721 ttgtcctgca ccaataattg caattttctt tgcattcatg atcttttgct gaagagccgt
    51781 tacgttttgt atctttttaa ctgggtgaat aagcgttgat tctgcagaaa tatttcgaaa
    51841 cttttgattt gaaccagtcg ctagaatcaa acgatcaaaa tccaattttt ttcctcctgc
    51901 taaaacgact tttttttctt tcaatcctat tactgtcttt tctgtgtaaa catggattcg
    51961 atagcggtca gtcagttctt ctttcgtgat ccaagaaagt tgtttttcac tggtaacctt
    52021 tccttttaat atcaaattga acccgctggg aatccatcct aacttcgatt gcttttcaat
    52081 caaatatatt tcacttgttg gcatcaattg gcgaagataa atagccgcat gaatccctgc
    52141 aaacgacccg ccgacaatta caatgttcat ctgcattcct ctttcttata aggtgttcta
    52201 ctgctaactt ctcaatcaga aaacacagta ttcataactc gctttcaacc ttatgataca
    52261 tagcgatgca gcagaatcaa ccctctccat cataccgtgt tctaggtctg cttctcaata
    52321 atgtactagt ggacctaatt gaagagtatc atttctgaag agatgtttca aaaaatgtac
    52381 tcttataaaa gaaaaaaact cgccttttac gtacctctgt ccaaatagga aacagaaaag
    52441 aacgaaaaga cgagttttag cgtgtgtaat gtaatagtta gaatagacac atcatttatt
    52501 tttaattctt taatgcttca acaactgctt cgcctaattg atgagcagat tgaggatttt
    52561 gccctgtaag aagccgccca tcaatttgaa ccacttctga aaaagctgct ccagactgat
    52621 agtttgctcc tttttctttc aaagcatctt ctgctaagaa tggtacttca ttcgttgtac
    52681 catttgcttc ctcttcttca ttactgaacc cagtcactgt acgtccagct aaaatagatt
    52741 ttccagactc atctgtaact ggcaacaatc ctacaacacc gtgacaaaca gctgagacca
    52801 gcccttcatt tcgatagatt tgtgaagcga ctttcccaag atctattgct tctggaaaat
    52861 cccacattgt tccgtggcca ccagcataat aaaccgctgc ataatcattt gcatccacat
    52921 catcaggacg taaggtattt cccaaggccc gatttctgaa atcttcatct tcataatagg
    52981 cccaatcgat ttcatccata ttcaaaacac tttgcggttc taaaggtaca tatccgcctt
    53041 taggactgac aaaatctgca tcgatcccat tttttactaa tacatcataa aaatgagtca
    53101 gttcacttaa ccacaaacct gtaggacgct cgatcttttc gtacttttct acatttgtta
    53161 atacgatcaa tactttcatt ttcccatcct ctttctataa aaattgcgtt attgataacg
    53221 tgctttcaag aaattatata atgggcttgg caaataaagc tctttatatg cttcttcaaa
    53281 aggtttcgtt acaaattcat cctcacggtt ttccaataat ttctctgccc agtcaggatc
    53341 gacgatcatt tgctgtccaa ttgctgcaag ttctgcatat ttcaatacct gctctacatc
    53401 ttcgcgattg cggatcccac cgacaccaac taaagggatc tttccttgaa tcgtgttatg
    53461 gaccacttca agaatcgatt tatcgttgta tttatcagaa cgagctattc gatcatacat
    53521 atttaatgaa acatgcagat aatctagttt tgactcacgt aatcgttcaa gaagccagat
    53581 cgtgtcttca aaacggatac ctggtgtttc atattcttct ggtgagaaac gataccctac
    53641 gatgaatggt tttttagcat attgttcaac cgctgagaaa accgttgtta ataattcttc
    53701 aataaaacga taacgatttt ccaagctacc gccccattga tcctctcgtc tattcgaatg
    53761 cggagagaaa aattgttgga tcaaatacgt atttgctcca tgcaactcga ttccatcaaa
    53821 tcctgattca atcgctctac gtgtggcttt gccaaatgct tggattgttt caacgatttc
    53881 ttcttcactc attgctcgtg gtgtttccgc atcaggacgt tttgctgcaa ctgcacttgc
    53941 agatacaggc tgttctccag ataaagttgc tcgacttgtc attcgtccac cgtggaaaat
    54001 ctgaataatc gcttttgcgc cttctccttg gattgctttc gctagctcac ttaatcgagg
    54061 aatcatttca tcatgagcga tgctgagttc acctggccag ccttttccga tatcttggac
    54121 atttgcagca ccagtaataa cagcaccaag acctttagaa cgttgtttat aataagtgat
    54181 ctcatcttcg gtgatcactc cattgaaaaa gctgagttgt gtcgtcatag gcgacagcat
    54241 caatcggttc ttcaattgaa ctcctgaagg taaagtaatt gattgatcaa attgtgacat
    54301 tgtcattcct cccataattc gctctgatta acctatcgag aatcatctat cattaaacca
    54361 ctcgattagt tgtacatgca actaatttgc ttaaaaaatt ttattttttt tgtaacttat
    54421 ctgttgcatc attcattgtc tgggctaatt ctttacttgc ttcatttccc aaaactgctt
    54481 tgtatgactg atgaagttct tcccagctac catcgacttc cttagcaaat tggcgtcctt
    54541 gttctgtaag ataaactaat gacaagcgac cttcgctaac tgttttgacg tatcctttat
    54601 attctaattt ttcaacaaaa cgagcaatcg ttgatggggc ggaatagagc atttgtgcaa
    54661 tatctttttg tggtattcca tctttttctt ttaatatcaa taaaataaaa ccataagttg
    54721 gtgccagacc tgtccttcta aacgcttcat cagctaattt attcaacatg cgatctagct
    54781 ttttcacgct aaagaaaaga cattcatcta acgctttttc aattggcttt tccatttcat
    54841 cccctccatt ggcgtacata tcatagtatg atttttattt tttgtcaaaa aacacggaat
    54901 aatgtccgcc tcctctgtct agatttgaaa aaaagaagta gccatcttca aagaatttcg
    54961 gcttgttttc gacaaaactc cttctggaac accgtgaatc agaggttgtg aaaaagtcgt
    55021 ttagttttga gtatgaagaa aaattttgtg aaaatggctt tccacatttt tgcataaatt
    55081 tggcttaata ccgaaaaact ggcttttgaa caccgtttat atcagaggtt gtgaaaaagc
    55141 cgtcctgcat caagtaataa gaacagccaa acaaaaatag ttcctcatat tttgtcgttt
    55201 tttgagctaa tgccgatggt cagctgattg tacaccgttt attgagaggt cgtgagcctg
    55261 ccgttgaact ccgagtcaca aggagcaatt tcaaaaaaca gcttctcatg ttttatgact
    55321 atggtgactt gtgatcgagg agttggcagg agaatactgt ttattcgtaa agaaggggct
    55381 gtgacaagac ttttgtcaca gtcccttatt tccttttatt ataggatttc gccatttgat
    55441 tggatgactt gtctgtacca atcaaatgat tttttcttta accgtttctt tgtgccattc
    55501 ccttcgtcat cttgatcaac atagatatat ccataacgtt ttgacatttg tgaagtagaa
    55561 gcgctgacga tatcaatgca gccccacgac gtataaccaa ataaatctac tccatctttg
    55621 atagcttcct tcatctgctc aatatgctgc ttcaaatagt caatgcggta atcgtcttga
    55681 acggttccat cttcttctac tttgtctata gctccgagtc cgttttcagc tatgaacagt
    55741 ggtttttgat acctatcata taattgattc aaagcaattc tcaaaccctt aggatcaatc
    55801 tgccagcccc attcacttga tggaagatac ggatttttaa ttcctccagt tattaagttt
    55861 ccttggaccc cttcccaatt ttctggatga gcactgactg cactagacat gtagtagcta
    55921 aaagaaacaa aatcaacagg gtaggctgct aagatttctt catcacctac ttctattttt
    55981 aagttgacac ctttttcttc aaacattcgt tgcgtatacg ctggataata tcctcttgct
    56041 tgaacatcac taaagaacaa agaagttctt tgctgctcaa ttgttttttg aatatcatcc
    56101 ggatcacaag aatacggaac aagaagctga tagctgatca tacaaccgac ttgtgaacct
    56161 ttgataattt catgacaagc ttttgtagct aaagcacttg ctataaactg atggtgtgca
    56221 ccttggtatt tcgcttgttc caaatgggga tggttttctt caattactcc tacgctaaca
    56281 aaagggtgat gttttacaca gttgatctca ttgaaagtca tccaatattt tactttattt
    56341 ttatagcgtt tgaatactgt ttcagcgaaa cgaacgtaaa actgaataag ctttcgatta
    56401 ggccatccac catattctgt aaccaaatat aacggcattt cataatggga aagagaaacg
    56461 actggctcaa tcccatattt tagacattcg tcaaacactt gatcataaaa aaataatccc
    56521 gcttcattgg gtgtttcttc atcaccatga ggaaaaattc ttgtccatgc gatagacatc
    56581 cgatagcatt taaaacccat ttcagcaaat aaacggatgt cttctttaaa gtgatgatag
    56641 aaatcatttc cgtgtctttt aggataataa tacttgctgt tgggatcctg cgccgctttt
    56701 acttgctgat gcgtcatcat atgccattga tctgtccatt tttctttagg taaatcgctg
    56761 tcgaatgtat acacatcaga cacagataat cctttttcat ctacatccca tgcaccttca
    56821 cattgattgg ccgctgtcgc tccgccccat aaaaatcctt ctggaaattt tttcatatcg
    56881 atccccctaa acttgctagt tttcttgttt gattattttt cttatgacta gtaatgatat
    56941 ttttgaatct actactattt gtaacaataa ccattgtggt cggatcatat ccctctttga
    57001 ttaattcttg caaatctact tccatcaata aatcgccttt acgtactttt tttccatcag
    57061 atactgcact ttgaaagtat ttgccattta aattcactgt atcaataccg atatggatca
    57121 gtatctctgc tccttcttca ctgactaccc caattgcatg tttcgttgga aaaactgttg
    57181 aaacttcccc gtttacagaa ctgtagattt ttccgtccgt tggaatgatc gcaaaccctt
    57241 ctcctaaaga tccactagca aatgttggat cgtttacttc agataaatca attatttcac
    57301 ctgctgcagg agtacttaac actatatcct ttgaggattc ttcttcgatt tcatccttgt
    57361 agccgaaaag aaaagttagc atacaggaac tgatcatcgc taagaaataa ctagcaacta
    57421 gccaaacaaa tccttcacca atataaatcg ggaaagacaa aatacttctt gtagcaactg
    57481 ccaaagcacc ggctcctgcg gcaccagcta ctccaccaaa tatagctcca catatacaag
    57541 caatgtaaaa tggtcgttta tatttaagag tcacaccata aacagcaggt tcagtgattc
    57601 caaataatgc tgtgataaat gcagataaag ataaactttt tactttctta tttttcgttt
    57661 tcaaaaatac cccaagtact gctcctgctt gcgcagctac ggcagtcata catgctggac
    57721 ctagcgtatc acgaccgtag aaagaaagat tgttggtcat tactggtaca agtccccaat
    57781 gtaacccaaa aatcactaac acttgccaaa atccgccgat aacagcacca gataaaacag
    57841 ggctaaagtt ataaacagct aaatatccag ctgcaatcag ctgacttgca taatctgcaa
    57901 ttggacctac aactaataaa ataattggga ccatcacgat gatacaaatg aatggtgtca
    57961 ataaatttcg aatactttcg tgcaagcttt tgcgaatctt aggctcaata taagaaagaa
    58021 cccatacagc taaaattgct ggaataaccg tacttgtata ccttgctaga atcacgggca
    58081 tccctagaaa tcgcaaggtt atgctatcac tatatgcact gacaatcgta ggataaacga
    58141 gagctgctgc aataaccata gcgatgaaac gatctgtatt gaactttttt gcagcagtat
    58201 atgccaaaaa tataggcaag aaatagaaaa atgcatcagc tgctgcattc aaaatgatat
    58261 aagttcctga ttcagtagtt aataaattca aactcgtaca taaggcgagt actcctttga
    58321 tcaaaccact tcctgccaag acgcctaaag tcggggcaaa aacagcggcg atcatgtcta
    58381 taaaagagtt taaaatgcct tttttctcag ttcctctctt tccactagat gcatcatctt
    58441 ctagtttcat ttgtttggat aatacgtcat acacttcatt tactgcattt cctactacga
    58501 cttgaaacat tcctccagct tcgactacag tgatcacacc ttctagttgc tctaccttct
    58561 ccttatctgc cttcttatta tcttttaggg taaagcgtaa ccttgttgca caatggtaaa
    58621 cattgctgac attttcttcg cctccgacaa atcggacaat atctttcgct aattgtgaat
    58681 agtccatttt tacttccccc ttgttaatta atgccgtagc aatccttctt acaagataag
    58741 tatagttctt agaaaacggt ttctccattc aattagtacc ccttctaata gcgaacgaaa
    58801 ctgtacaata gtgtgtatgg tttacttagc cgagcaaatc actcactgct tgaaagaaaa
    58861 caagtatatc gtttctctta tagtcaaagg agacaaaaaa aacacgcttg atcttccttt
    58921 gctgatgtat aagtggtatc tcaagctgat actctgtgat ttttgtttct acttggcttt
    58981 tgataagaca gcacaacaaa gtctcggcat ttaacggaag cataactagg tcagaactag
    59041 gagagattag ttgctgaatg gaatctatct ttttatggat ttttatttga ttttcttctt
    59101 tgtagtaatg atcaagcagt tttgttttct ttttttcttc aactatggtc agcttttcac
    59161 gcaaaatctg ataaatctcc caagattcaa actcatctag aacactaggt agataaatca
    59221 aatcatccca ctcaaaaata agctcttgct cagtagtcaa aattgcatca tattccgtta
    59281 ttttgtttga ttgatttttg aaaagataca ctggttctat ccggcattct ttgatccaca
    59341 tgttcatact ttgttgaatc tgttttttta gtgtattcaa aatactaatt ggctggttac
    59401 taacaatcag tatctcccct tgttttcgaa aaggattcaa cgcttcggca agatacaaaa
    59461 caaaataagc gctttcagct aaattgggac gtaattgaaa atgtattggg aagaaacgcc
    59521 gaattaaata aatttctaaa ggataacggg agatgatctt ttgtacaaaa tgattcatgg
    59581 tattatgtcc ggcatccatc ctcgttttca tttgtttgat atgggttagc aaaaattctg
    59641 tttcatggaa caataacgaa acaggaagat ctaaaaaacg aataatcgtt tgctcaaatg
    59701 ctcttagatt cttctctatt tctttgtttt tttcatcatt aatcatcaaa taatttaact
    59761 ctaatagtcg attttcaatt gcttgttttt cttgattgga aaaagaatag ggtagttctg
    59821 atgataactt ttttgtgagg gtctctacca tcggaataaa taatgtatac ctgtttgttt
    59881 tttctaaaag ttcttctctt cgaagaatgg tcaaaacgag ataccgagaa aatcgtatga
    59941 agtcctctcc tgaaacaata taattatatg atataagaac ctcttttaat gtcttttgga
    60001 cagtcggcat gatattggaa aaaattgtac tgatttgttg aggcaacctt gcgtgttgga
    60061 tcaccgtttc tgttccaaca agagataaga aaattctttt tgaattttct tcagcaatga
    60121 tttttagtcc ttttgtcgac gaaacttcca gttctaattt aggattgcgc tcgatccaac
    60181 gcaaaatcgt ttttatttgt aatgatacgg ctgtttttga aagaaagaaa atgtctgcta
    60241 tcttttgcat actgacatac cctttttgaa acaataagta cgtcacaata gttgaagctc
    60301 ggaaatccat gctggaatag attttatgtt tcgtcacctc ttgtatgatt tgctgtttag
    60361 tttcagattc aattgattct aaaaaataac ctgaacgttt atttgactgg ataatgattt
    60421 tcttctcgta gatagcaagc atatttttga tttcagtttg gatcgttttc ttgttggtac
    60481 ctaaagcttc agctaattct tcgcttgtta tccaatgatt cttatttctt aatactacaa
    60541 gaatttggag ttgtcgttta tttaagtcca tttgcttaca cctcctcttt gttataaaca
    60601 tacaggaaaa acctctcaaa tgacaatagt cacttgcaga ggtttaaaaa tcatttgaag
    60661 aaagatctat attcaaggtt tttaccatta gactggataa tttgtttata atattcaaaa
    60721 ctatcttttt tcaatctcct aaagcttccg ctcccatcat tttgtctatc cacataaata
    60781 aagccatatc gcttcctcat ttcccctgtt cctgccgata cgatatcgat tggtccccac
    60841 cataagtaac caatgatttg gcaaccatct tttattgcct cagcaatttc ctgaagatgt
    60901 atttttagat actcacaacg ttttggatcg tggattcgat tcaattcatc tggtgcttca
    60961 tctagtccaa tgccattttc aactatgaat aatggtaatt cataacggtc tgtcaattca
    61021 ttcatgacat aacgaaaccc tagaggatca attggccaac tccaaggttc gggagatttt
    61081 tccttcaaaa agggattatc gaaaccattt gctccgccag tatctacgcg catttctgct
    61141 tcttttttat agacagcgct acgataataa ctaaatgcaa tataatctgc cgtgttagct
    61201 tgcaagcact gttcgtctcc atctaacatt actggtgcac agtcttcttc cttccatgtc
    61261 ctgtaaatat aagctggata atgccctcgg cacatgacat cggagaaaaa ccatgaattg
    61321 cgtttaaatt gcagtgaacc aaatacattc tctggatcac agtcatatgc ataagtcgct
    61381 aatgcagaaa agctacacat aatacccatc ttagcatttg gatcgatttt ctttaataat
    61441 tgagtagcac gggcgttcgc tagaaacata tgatgacagg cttgataaat cacttttttt
    61501 gttagtgtag caatgggttc aagtttatct ctagcaggga atgtaaccaa tccagcagct
    61561 gcataaggca tacgaaaagc attattgatc tcattaaagg tcatccaata tttcactttc
    61621 ccttggtagc gttcaaagac ggtctgcgca taaaattcaa aaaagtcgat taattttcga
    61681 ttttgccacc ccccatactc tcctaccaat gctaaggggg tttcataatg actaagagta
    61741 attactggct cgatatcata tcgatttaat gtattgatta gtctgtcata aaatacgaga
    61801 ccagcctcat ttggcttctg ttcgtctcct cttggaaata ttcgtgccca tgagatgctt
    61861 gttcgaaaag cttttaaacc taactccttc agtaaacgaa tatcctcttc aaatcgatga
    61921 taaaaatcaa tcgcttcatg agaaagataa tggagtgatt cgtctaaagc aatctcccaa
    61981 atcttttttt cttcattcca ctgaatacta ggatgctggt tcatgatccc gataagcgta
    62041 tctgtcacat taggtaattt gccgtcttcc aaccatgcac cttcacattg attagcagct
    62101 actgctccgc cccataaaaa attttctgga aatatttcct gatccataac tatctctcct
    62161 cgctatcaac aatttcttac ttgaagtata gctcgattca tcaaaacaag atattctaac
    62221 tatttcggca gaagagaaga aaaaaattga atgctactct tcatttttaa tatttatata
    62281 taacaaatac ataagacgat ccccgaaaga aaacactcgt taaccatcta agcaaacgat
    62341 ttattttact tccaacacaa atgcttcata aggtcgtaaa tcaactttgc cgtctggtaa
    62401 ctgtttcaga ggataatttg acacaataac ccttaaagct tcacgtggaa tagtgaacgt
    62461 ctgcttttca ctggacatat tacaaataac gagccattgc tggtcttcat atatgcgaga
    62521 ataggcaaag acatgctcag gcgtcttttc cactaattca tagtctcccc agacgatgat
    62581 gtcatgtttt ctacgcaaat cgatcaattt cttgtacata taaaaaacag aatcttgatc
    62641 tgctaacgct tcttctgcat tgatttcttt ataatttgga ttgactcgaa gccatggaat
    62701 tccagtagta aacccagcat gttcacgggc gttccattgc ataggcgtcc tagcattgtc
    62761 tcttcctttc gccttgattg attccaagat ttcctctttt gtaaatccag aagaaatcct
    62821 ttcgttatac atattgattg tctcaatatc ttttgcttcc gcgatatcat cgattgggca
    62881 attcgtcatg cctaactctt ctccttgata gatataaggg gtgcctttca tcatatggag
    62941 caagatagca aacatcttgg cactttcttt tcgatacaca tcgtcatttc cccaacgaga
    63001 aacaattcgc ggaagatcgt gattattcca aaataaacta ttccatcctt catcacctaa
    63061 agatgtttgc catttggata atactttttt cagttcagag atactcaagg gtttcaaatc
    63121 ccatttgtct ttgccttctt gctgatctaa tcctatgtgt tcgaattgga agaccatgga
    63181 taattcattt cttttaggat tggaataaag tttagcgatt tcggtagttg ctccccatgt
    63241 ttcgccaaca gtcatcagat ttttgtcacc aaaagttgct tgattcattt cctgaagata
    63301 ctcatgcagt ttaggtccat tacttgtgat ttctttatcc ggttctttgc caatcatatc
    63361 gatcacgtcc atacgaaagc ccccaatacc tttatcgatc cagaaattca tcatttgata
    63421 aatctcttgg cgaacctgtt tatttttcca attcaaatca ggttgacgct tgctatacaa
    63481 gtgcagaaaa tattgccccg ttttttcatc caactgccaa gcagaaccac tgaatattga
    63541 gcgcaatcta ttaggctctt ttccattgac cggatcacgc caaatataat agtcccgata
    63601 aggattttct ttatttttac gggcctcaat gaaccacgga tgttcatcag aagtatgatt
    63661 caccaccaga tccatgatga tacggatatt tcttttcttt gcttcttcaa tcagttcttc
    63721 catttcttcc atcgtaccga attctgccat gattgcttga taattactga tatcataccc
    63781 attgtcatca ttcggagact cgtatactgg agaaagccaa attgcatcaa tacctaaata
    63841 cgccagataa tccaacctgg aaataatccc ccgcaaatct ccaataccat cttgatttga
    63901 atcttgaaaa cttcttggat agatttgata aacaactgaa tggtgccacc atttttgttc
    63961 catgattttc ctcctataaa tggatgtttc tattttttgc ttaatcattt attttagtct
    64021 ctctcactaa aaattgtaac gctttcaaat agctattgca ccttgttatc ggtaacagaa
    64081 taaaacaaaa aaacagctga ggaaattccc tcaactgttt tttgaaagga ttgatttatg
    64141 cagggaagaa tgctgatttc acaacttctt tataaacggt gttcactcag ctgtcccttg
    64201 gtattagctc aaaaaacggc aaaatataag aaactatttt ttcgtttttt tctctaatac
    64261 tcaggccaga acgctgattt cacaacctct ttatttcaca ttcaatatcc acatgaatcc
    64321 cacaaataca aagaacagac catacatgat tggagatact tcttttcctc ttttagctgc
    64381 taacatggta attggataga agataaaacc taatgcaatc ccatctgaaa tactataagt
    64441 caaaggcatg ccgatcaaga tcaagaatga agggatcgca atctctaagt ttccccattc
    64501 gatttgtcgc aaagattgtg ccatcaatac tcctaccata atcaatgctg gtgcagttac
    64561 ttgtgaagta acaactgata gtaatggaga aaagaacaag cctaacaaga agaaaatccc
    64621 tgtagtaata gctgtgatac ctgaacgtcc tccaacggcg ataccagctg atgattctac
    64681 aaatgcacca acaggagaag taccaaataa ggaacccgca agcatagctg ttgaatcaga
    64741 agctaaagct ttccctacac gaggcatctt gttgtctttc atgaaacctg cttggtttgc
    64801 taatccaact aaagttcctg ctgtatcaaa gaaagtcaca agcaagaatg tcagcactac
    64861 gacccacatt tgaagagaat tgatgtcccc tacatgtttt aatgcaacta aaaatgttgg
    64921 tttcaaactt ggtgctgcgg caacaatttc agaaggcatt ggaatcaaac ctgtgaccag
    64981 acctaaaatc gttgtagctg ccatcccgat gaagatgcca cctggtacac gccgaacaag
    65041 caagatagca gttacgacta atccaaaaat cgtcaaccaa gtagaaccaa cgttgagtga
    65101 tcctaatcct actaatgtag attcattcga aacgatgatc ccaccttcgc tcagaccaag
    65161 gaaagcgata aatagaccga taccgccaga aatcgcatat ttcaaatctg ctgggatcgc
    65221 atcaatgatc atttcccgca gcttgaagat tgtgatcaaa ataaaaatca aagaagcaac
    65281 gaatacgccg gctaatgctg tttcccatgg aatccccatt cctaaacaaa cagaataagc
    65341 aaaaaaagca ttgatcccaa gagcaggtgc cgttccaatt ggataacggg ctaatacccc
    65401 cattaaaaca cagccgatcg cactggctaa tgcagtcgca gtaaacactg ctccttcatc
    65461 cattccagaa gcacctaata cagttggatt tacaaataag atataagcca ttgagataaa
    65521 tgttgtaaat cctgccagta cctcacgttt taccgtggtg ttcaattttt ctatttcgaa
    65581 gtaggaaagt attttttcct tcatcttcca tccccctaaa tccgaacatt ataaataaag
    65641 tccgttaaaa tttcgattta ttaataaaac aacgtgtttt atcatatact aaaacaaaac
    65701 ataagtaaac aaaaaattcg gattttaagc aaaatccgaa cgttccatct gattaaatcc
    65761 ctttatctca aagttcatga acattcactt tggattacaa gaatttcttt attgtgttaa
    65821 taaagtttct tcattctagt ctcaaaaatc aatagtgtga tttgatttta ccatttcgtt
    65881 tctgttcttc tttgatgaat tcttttgtat cgacaggatt cagattattt agtccgccaa
    65941 aacctgtatc gaccattttt ccccagcctt ttgtcttctt ttttcctgat ttgagattct
    66001 ttgctcgaag cttctcacta tgttttgctc gccgatactt caaataacct tctaatcttc
    66061 ccattagatc cactgttttt cctccttttt attcaatcag acgactcagc ttttcctata
    66121 acaaaataat tgccttcagg gtcagaaaaa ttgaaagtca agatgccatt gttatctgtg
    66181 atttctcctg gttcttccat gttctcgtag atagtttcaa attcatccgt aaaaaatact
    66241 aaagaaggcg gtggtcctaa tacctctggt gaaaacttct gcacaaatac ttttgggaat
    66301 acgcctaatt ctaattcttt tgagatgctg agtacaatac tcttaaattc ttctggcaat
    66361 tcgattgttt cagaaatttc tgcaccaatt ttttctacaa agaatcggca aatcatctct
    66421 acgtcattga cataaagcat cacacgtgtt ttttgtatca tcatttgacc cttctttcta
    66481 tttgattttc tttcctgtct ataaactgat tccattatat cacgaaagcg caaacacctt
    66541 gtgtttgata ctattcaaga aaaataaagc aatagtttct aggattgctt tcctccacaa
    66601 acttttttta caaaaaaaaa aacggcaatg aatgccgctc ttcttatttc gattctttta
    66661 taattctgct tctgattcat ctttggttag tgtgtgtcta acactagtta cgccaaatgt
    66721 ttgatcgatt ttttccttca acgcttcgat tgcctgtgcg ccacgtgccg cttgttcagc
    66781 attgatggat tcaatgacca gcaccgctgc ttgtgtttct tccgtcagca tcgttctttg
    66841 ggcttcacgc cagttgagac agcgacagat cgctccttgt tcatcatagt agatgatttc
    66901 ttccggaagt gccggagcat cggaatctgc acctaaaggc aggaatgatt cgccaccttg
    66961 ggcttttcct aaatgcagat ttcctgcgat cttttcgata tcttctccgc cgcaaggtac
    67021 gccaaaagac aaggaaatac tattatagat atctacaagc ggattgattg ggaaaaattc
    67081 ccgttcttga tttgcacgtt tcagtaaagc ttcaatagaa gaacgtgcac cttttttagt
    67141 cttgaatgtg gtaaatgcct gacgccactg agcaatgact tcgttttggc tgaatgtttc
    67201 ttctgtaagg taatttcttg cttcttttgc tgcctcattc aataattgat gatacgtttc
    67261 ttcactttct tttgttacgt ggttatcgat accatttacg gataagattt cgatggttgc
    67321 ttcaggaaat acttcccaga aattggtatc cactattact tttttcatct gttcacacct
    67381 cttgattaga ataattgctt gatgaataga tagtctgttt ggggatcatc tcccatataa
    67441 aaaacatgtt cgctgtattt gataaatcct tttttacgat aaaaagcgag cgcaacatcg
    67501 ttgtgttccc aaacaccgag ccaaatggct gttttttgct tttcttttgc tttttcaata
    67561 gctgtatcta gtaaaaatgt accgatacct tgatgtttaa atttttttcg tacatagatt
    67621 cgctcgattt ctaaaaaatg atcagccatt tcctcagatt gactcgttcc tgtatttagt
    67681 ttcaggtaac ccgcaggctc ttgatcgata ctcactagga aaaaatcggt ttctttatct
    67741 tttagctctt ctgtaagttt ttctagtgca taagcttgtg tcaagtaatc agctaaatgc
    67801 tccggtgaat tatcttttcc aaatgtatct gtaaatgttt cgatactaat ttgttgtagt
    67861 aagtctacat ctgaaggcgt catttttcga atttcgtatt tattcacggc ttcttccttt
    67921 caatagatcc ttttattgcc ttttttgaca aaattccaat cttcgctaac attcttgcat
    67981 actttattta aaagatattc caattgtttt gcttcttcgt cagaaagacc atttaatgcg
    68041 actgcattgg agtagttgtt ttctcgaatg atgaaaggat agatttctgc tcctttttta
    68101 gtcggataga gtttcttgat ttttttattt tctttatctt ccaaacgttc gatcatccca
    68161 ttggattcta atttcttgat tgctcgggca gtcgttgtac gatctacttt gatcatttct
    68221 gctagttttt cttggatgat tccaggattt tcgcaaatac gtactaaata aagatactgt
    68281 cctcttgtta aatcgacttc tttgaattcg atattgctaa tagaatctag cgctcgggca
    68341 atcattccga tgtctcgaag gatttcagcc atttcatccc acctttattt tgtttgtaag
    68401 actagttcac ctctttttgt tgcaaatgca actattttca ataaaaaaat caagttcttt
    68461 tttaataact agtaaagtat attcttttct tcttttacga aaaagctcaa tcacaataga
    68521 tctggttttt gttttctaaa ataagtaact gtttcttcgt tgttcgcttt tctgatagct
    68581 ttggcaactc ttctatacta aaaaatccca tgttggaagt ttcattattc tcaataaact
    68641 tggcctcttc accgtggatc gcacaagcaa aaacaagttt ataatactga aaaagctgtg
    68701 gaatatcttt ttgtttattc gtatcaaaaa ctgctcgcaa ctgagtagtt tctactgtta
    68761 atcctgtttc ttcatagact tctttacgca cattttcttc aggagacaat cctatttcag
    68821 caaatccacc aggaagtgac cattctttcg tccgtttatc ttcgattagt aggaccttgc
    68881 catctttttt gatataggca cgaacatcta cttttggtgt tggatgtcct tctccaatcg
    68941 ttgtgagcgc ttttatttct tcgaaagttt cttttcctat ttcactgatt agttccaatg
    69001 aaatcgtccg gatctcctca aaacgctctt tatcaaatac atcttttcca taatatagac
    69061 cagcttgaga aagtgcgagt agtcttttgt attgagccaa cttcttgttc attctcttcc
    69121 cttctttttt agcaaatgta tgactatgta atcaagtata gaagactggt ttaattacgg
    69181 caaataaata taatgaaatc tgcaataaat aaaagaatgt taaaaaactc gagaacaaaa
    69241 gacattcgac ttctctgggg ctgtgaataa atggcgttca aaagcttgca tctgcggtaa
    69301 taagccccac caaacgaaaa atatgacgag ctattcttgt ctggctgttc ttattaattg
    69361 aggcaggaca gctttttcac aacctcccca ctaaacggtg ttctcctacc aactcctcgg
    69421 tcacaagtca caatattcat caaacatgag aagctgtttt tttgaaattg ctccttgtga
    69481 ctcggagctg aacgacaggc tcacgacctc tcggtaaaca gcgttcaaaa gccaattttt
    69541 cgatattaag ccatttcttt gttacttatt gtcattgatt tctttttcta atttatccaa
    69601 tagtggagtg taatccactt gagtatagtc tgttacatca aattcatata gtgttcctaa
    69661 ctggaatttg tcatattttc ggtcggcgat gatctttttg aatgcttctt tcgtaatatg
    69721 attggtccct ttcgttcgat cttccaatac gtcaccatag tgataatgat ccatgatata
    69781 gctcaaatga cgatctgatt cacgatcacg tttgtaccga cgttgccata acacttcaaa
    69841 gtctgctgtt aggcgaatcg tgatcacctg atatccgtat ctatctgcta attcttggag
    69901 tcgtgctttt tgcttatcac taaaaggata ctcggacaca atcactttct ttcctgcttc
    69961 catatacaaa tcaagtgctt tgtaatagaa aggataaact ttcgtccttt cttgttccgc
    70021 ccgttcttcc aaattgttaa acccgatgga ttctgcatag tattccttga tttcatcgag
    70081 cgtgatggca tacatatctg gaaatcgttc ccgtagttta ttcataagat atgtttttcc
    70141 tgtaccagga ctaccagcca gaagaatgaa atactttttc atctcattta tttcctaagt
    70201 taattggact ttccaagttc ataaacagtc caatcttatg cttgacaatt tcttttactg
    70261 cttcatttgc tggaatcaca ttatggcgaa gagacttgtt gatttctgtt tcactaaagg
    70321 tttctttagc tactttcgtc cagttgacta aaagctccgt tccaacattg aatttgcgga
    70381 tcccgttatt gatcaattca ggataatctt cttctttcac acctgttcct ccatggataa
    70441 ctagggggac atcaactact gcatcgattt ctttcagcaa gggaatgttt acttctgttt
    70501 ttgatttgaa ttgtccatga ttcgtaccga tagcaatagc taatgcatcc acgcctgtag
    70561 cttctacaaa tttcactgcg tcttccggtc ttgtatatac cttgtcattt tcagcgacat
    70621 ggattccttc ttctgtaccg ccgattgttc caagttctcc ttctacggaa acaccgtgcg
    70681 catgggcata ttctactact gcttttgtct tcaggatatt ttctttgaaa ggcagatggg
    70741 acccatcata catgacagaa gtatatccgc tgtcgattgc ttctttgata tcatcaaagt
    70801 ctcgggcgtg gtctaagtgc aagactgcat caaccatttc ttcttctgca atagctgtca
    70861 ttacattgac taacacatgc atgccgatat atttagcggt atcgacactt gtttgaataa
    70921 tgatcggcga acccatttct tttgctgcgc ctagcatagc aggaagcatt tctaggttat
    70981 gcgtattaaa agctccaact gtaaaattca actcttctgc tgtttttgtt acttctttca
    71041 atgttgtata catcttttat tgccacctta tctttttatt tgtttccttt gatcgttact
    71101 tgttttgcaa tttgtcgcat ctcatccatt ttgcccatgt agtaatcgat cccttgatca
    71161 tcaccagcac gagcagcatc tgcacgcttc tggttataga ggctcatcag ttttttatac
    71221 ccatctccga tcgtctgttt attttccaaa ctcttttcta aatattggat ggcttgatcg
    71281 ttcacataca attcagaaaa tttaagtcca acttgttcat aaagtttcgc taatttatgc
    71341 ttatcttggg tagtggaaat ctcttgtttc aattgtgtaa tctctgattg aatcttttcg
    71401 gtcgcttctg gcgatagggc tttttcttct tttgccagaa cttttttcgg ttctttttct
    71461 tttttcttaa aaaatccaaa catcattttc cctactttca attaaaatgc tttcaaaact
    71521 gggcttaaga tccaggcata taagagtgct gcggctactg tatctacatc ggttgctgta
    71581 gcattgatga atcccatcga attaaagatc gttactagca aagcgggcaa taatgtaata
    71641 aagaaaccat gagcaatacc gccaatgatc gctcctcggc gtccgccaac tgcgttgcca
    71701 aatatccctg ctgtccctcc ggcaaagaaa ttggttagca taccaggtaa aatcatcgct
    71761 aagccgaaca tgggcaaagt aaacatggca ataatcgtac caatcgttgt cgtaatgaaa
    71821 cctaaaatga cagcatttgg gctataagga aagaaaactg gacaatctaa ggcagggatc
    71881 gcatcaggaa ctaatttcat agctatccct cgaaatgccg gcacgatttc acctaacagt
    71941 agacgtacac cagctagcaa tacatacaca cccactacga attggatggc ttgtaaaaag
    72001 gcaaacatga tatagttttg atctcctgat aattcagaag cgaatggttc gcctgcaaat
    72061 aaaacagtga tgatatatag cgggaccatc acgaccatga cagacaaata agtatcttgc
    72121 agaaattcga aatgtgtcgg caacttgata tcttcgatcg actttttatt ttcgcctttc
    72181 tcaccaaaaa gcttagcaac accggcttca aataagtacc cgatcgtaca aaaatgacct
    72241 aaagcaatat catttgatcc agtgatttta cgaatgatcg gttgcgctac tgccggcata
    72301 gcaatggcga aacaagctcc gataaaatca ccgaccaaga tcaatacgat ccctcgcaga
    72361 ccggcaaaat agccaaagac tgtcgtcatc gttgccatcc ataaaattgc ttgaccagtt
    72421 aaaaaaatgt acttccattt tgtgaaacga gccaaaataa tattgaatac aaaaatggct
    72481 aagaacgtca gtgcaatatc tctacctaaa cccaaatcat tcattgcttg accattgata
    72541 gattcaatag aagggatgat cccttgcata tgaaatcctt cagtaaagat tttcccgaaa
    72601 taagttaaac ttccaacgat gatgctcgaa ccggcactca acacttgaaa tcctaggagt
    72661 gtctttaacg tgccagagat gacttgtcct gctgatttct tctgcagtag tagacccaac
    72721 atagcaatca atgcaatggt gatcgatgcc tgagtcaaaa tattttcgat gataaaattg
    72781 ataacgccca tgtttttccc ctcttttctt tttgtattta gataactccc ttatcttgca
    72841 gaactggggt gattttttct tcaatttcat tttttgaaac aatatttttc aaatagatca
    72901 tcgccgtttt aggatcaact gcgaactttt cgaactgcga acgaaaattt tctgctgtga
    72961 tgatcacatc tggtttcatg gaaactgcgg aagaaatatc acaatggtcc agtttggctt
    73021 ctactcctaa tttgttcaaa acatcctcag cagacatctg tgctgcaaaa ctacttccta
    73081 aacctgcacc gcatacgaat aaaatgttca atttgttcat ctttgttctc ccccgtatca
    73141 tttattattt ctcaactact gaaaaaagca gttgtttgaa atcttcgata tttgtgcatt
    73201 caatcaatcg atccaacttc tcttcgttgt tgatcaattc aattagttct ttcatgatgt
    73261 tcagatgcga gtaggagtct actgctgcca aacaaaaaat aatctttact ggatccattt
    73321 caggattacc gaaatcgatt ggttgctcaa tcgtagctac gctgactcct aatttattga
    73381 ccccatcttc tggtcgggca tgggctagtg ccatgtgttt gccaatcacg atatacggtc
    73441 cgtaatcatt cactgcacga atcatcgctt cgacatagcg ctcttcgaca atgttttctt
    73501 taaccaatgg tctagcagct agttcaatcg attcctccca agtagtggct ttttctttga
    73561 tcatgatatt gctgtccgtc aaaatatctt ttaacatagg ctggatctcc cttttgttga
    73621 tttctaaatt gtttgtttcg aataattttt ctaacttgcc atagatgatt cgatctactc
    73681 ggccaccact ttctttcatg acatctatta tttgagtgaa taactccgtc gattcatgac
    73741 tgttaggctc taaccgctgt agttcttcat ttcttttcaa aaagtcttct ataaccaaga
    73801 tattcgtctc agttaaaatc ggatcgacaa ctaaaagcgg cttatttcga taattcaatt
    73861 gaaaggtgct gaaaaccaga ttgacatcca atttatctac taattcgatt tcttttgaac
    73921 ttaaaactgc agtaatctcg atctgaggaa acttttcttt cagattctct gctaacagat
    73981 ttccagtagc catcccatgg ttacagacaa cgactgattt ataaacataa ttcaagtctc
    74041 gcttgattac actggcgatc gtcgaaaagt ggatgacaag aaaagctatc tcgtcctcca
    74101 gtatcttgcc accaattact tcttcgatcg taggaacaaa atgagtgact gcgcggtaga
    74161 ttgggaaata atttgttcgg atgttttctt tcaatggatt catgacttgg atatgattct
    74221 tgattcttac aatcagtgca gccatgtgct tatagagatt ttcgaataaa gcttcttcct
    74281 ttagatggaa aggtacgtgt gtctcgttct ctacaaattg gatcaattgg atcgttagta
    74341 attgagcttg tacccactcg attgaattgg agatatctct agcattgaac gtctcaatag
    74401 tgaaacgaag ataatttctt tctacttgcg ggacattgtc caattgaaat tcctcgatca
    74461 tgtggtcaat aaatgcagaa aagctactgt cttttatttc tgtatttttc caattaatgg
    74521 cagagataaa ttcatgtttc ctgattcgct ggatccagat caatgtaaaa agcaggattt
    74581 gttttttata aatatcatct tcttgtttca acaacttatt ggaatagatc tcctgtattt
    74641 ttttgatttc caccaaagga aaataatgga gaaagatttt ttgagccggt gttaattgtg
    74701 catcttgatt cataaagaag tcggtcattc ccagattctg attgataaaa tcatagatca
    74761 tcgtacggat agatcgttct gaacctttat aaaccagtcc ttgctttcca taactgacga
    74821 tctctatccc ataactgacc agtgttgctc gtaaccgtct catatcttca tctaatgtac
    74881 ttttagagat ttgaaattct tcttcttttt tgtttagatg gatcgggatt cggctgtaag
    74941 caacggctaa aactagatca aaaatacgtt cgcgccgatt caaaaagccg tctttcacat
    75001 cttttatttc agtttctaat cgagcttgct tttccttttc cagcttcaac aaaaaacctt
    75061 tgttgcgaat tgtacggatc tccggaagct ttttactgct caaccagata ttcgcttcaa
    75121 gaacttcctg acggatcgtc cgctgactga cattgaactc acttgctaga tgttttgctt
    75181 ttactggata ttgggctgtc atgattctgt gaagtatttc aattgttctt gttttcatag
    75241 aaatgatctc cttctgattt caagtatatg gttccgctta cataataaaa agtagatatt
    75301 tctgccactt gaagtggaaa gaaagtaagc aaagcaaaca aaaaataagc catatgcttt
    75361 ttcatctcct caacgaaaaa gacatacgcc tattattaca aaaattttgc ccatctatac
    75421 aaaaaagagg ttgtgaaaaa gctgtcctgc atcaagtaat aagaacaact aaactaaaat
    75481 agtgcttcct atttttcgtt tggttgttct tattatcgca gatgcaagct tttaaacacc
    75541 atttagtgga gaggttgtga cagagatgtt cagccttgag cgataagaag cgattttgaa
    75601 aaatcgcttc ccatatttta caaaatcgtg ccttattgcc gataggctat ctctggcaca
    75661 ccgtttattc agaaaaagga gctgcgacaa ggcttttgtc acaactccgt tcataaatat
    75721 ttcctgtcaa tccagcataa tcggctgaat aaaatcggct tgccatcttt tttctttctc
    75781 agaaaaatca aaataccata tctgagaaaa atactgtcgt tgtgtcttac ttcctgagat
    75841 caatcgccca tcttttcgat cgactgaata atcacagcat ctgaaatcaa ttcggatggc
    75901 aaaactattt tcgtggatct gtcgataatt tcctacttcc tgaatagtta tttttttagt
    75961 atgatttctt acaccgtctg ctttgttttt ttgcagaact ttctgatgtt cggcaaacag
    76021 cttgtctgta taacagcttc tggctttttc aggagtttct tcttcccaag cggattggat
    76081 cttcatgaat atcttttgga tttccagaaa ctgtgctttc ttttctttag ccgttcctga
    76141 catgcgggac aatatctccg ctttcagcct tttcttttgt cttttattct tgacgataga
    76201 aaaagcagaa acccctccta ctgacaaaac agctaatgca agaaatcccg tttgctcata
    76261 actagaagga cctgtacctg gaccataata cccataagaa tctctgccgt aagaacgact
    76321 gccaaaataa ctgcccccat atgaacgacc accaaatgaa cctctgcccg aacttcgacc
    76381 gctagatgta cctccaccat gaccacccgc gacagcgaat ccttgggtcg gcagagcaaa
    76441 caaacatagg cccactaaca aaatgattgc taaataattg atttttttca ttgtcttcct
    76501 cgttatcttt tattacaaaa aactattttt atgatagcct tgctaaaagg aagagtcaat
    76561 aaccagatgc ataaactgtt tttttagcaa ttttgtctta tttagtcatt gagtaacatc
    76621 ggacaaatgt atgtgtcggc agtccataat tcctctatct tcagcatgaa caagcttgca
    76681 gacaagagat ctgcgcttcc tccaggagag atttggtttt cctgacaaaa gtgcaacagt
    76741 gctgtaaatg gacgatttgg taaagcactt tgactagcag catgagcaag tttttgcatt
    76801 tccactaacg ttttctgatc actgcgatgc aatacgcatg tgtcatctag cgaactcatc
    76861 aaaactaaca acatatgcat ttgtttctgt acatatgaat cattatctag ctccttagct
    76921 gcttgaattg caagcctgat atgcggatac cctaatatcg cttcttcata tgcaccattt
    76981 acgccatatt tttgcttcac cctatgacca tgagtggttt ttttatgacg atattttgta
    77041 tcaggaaaag cagcaagctt gctgacatca tcaagtattt tcgataaaga aaaaggctgt
    77101 tccatactga ttttttgtgc aatgacactg atcaatagcc ccattgccca aatcgctcct
    77161 ttatgggtat tgatgccatt tgtagcaatc agcattgcct tttccgcttt tcgcccaatc
    77221 tcagcaattc tttctcttaa ctcctgatca atagcatgat gccatgctat ttgagccatt
    77281 tcttcaaaaa aaggagttag cgtcttagca gacttaagaa ataaagcata gtccatatcg
    77341 gaatgtgcac ccgcatccag tgcatccact aatccaggtt ttggacttaa tgttacttct
    77401 gcgatcaatg cttcctctac caacgcagcg agttgctgag tcactgcttt ttttcgttcg
    77461 tcatttatca tgacactcac tccttcttcc tactattact tgctgaaacc ttttttgata
    77521 gctacccaaa tgatatgaag taaccagctt aaagcaaatg cacaacttgc cgtcattaga
    77581 taagctacaa gaatcatgac tcctgaaggt aactgcagcc aactatcttt aaacaataat
    77641 aacagtactt ggaaaacaaa tacattggct aaatacgtac gataagcata aacagacaac
    77701 catttgaaca atggcaattt tggcgaatcg tttacaatca ttttggaagc gcctatgaag
    77761 acagcaaaga tgatgactaa actgtataaa ctttggatcg tattcaagta aggtgcattc
    77821 gcaaagctca agtctcctgg atgtgcgagc aatgaacgga cagaaaagaa cgcgataact
    77881 aaggcaacag gtaagaaaag ataacgtact ctgtccaaat attgatagac tttttcgtga
    77941 taaacaaatg cggctacccc ataaatcatg aaactagcaa caaaccgatc taataagtac
    78001 cagctgtcat gataaggccc agtcaatact tgtgtttgat agaacagata ccatgcgaca
    78061 tataaaatcg ttgaaccaat caatactggc catacatatt ttttattagc aaatactttg
    78121 taaccgagcc aaacaaaaaa cggcatgaac aattggatct gcagcatcat aacggtatac
    78181 cataaatgag gcgctccatc acctgtgaca tatttcagta aaaagcttgc agtatccgta
    78241 tacggagttt gttgttggac tgctggaaat agccaaagat aagccgtcgt ccatagaaga
    78301 tacggaacga ctagttcaaa aaacttttct ttcaaaaatt cccaataaga caaatgctga
    78361 cttgttttta ccatattata aacaattgca aaaataaaca ttggtgctgt gtatttaacg
    78421 atgacgtaaa aggtaccaag aaaagctgta tttgttgcgc tgtggctgtt tgccaaagca
    78481 aagctcaata tcgtttgcat cataacagcc gttacagctg atactttctg gaagtcactt
    78541 acgttgattt tgattttttt gttttcaaac atctctttct ctctcttttt ctttattacc
    78601 aaagttcttt ggttaattta ggtccttcga ctgttttcaa tagaattttt ttctctggct
    78661 ctctcaaata ctcttttagt gaaaaaccgc cttgccgagt cactacttgg gtatcgaatt
    78721 gctcaaaaaa agcaggatgc gattgaatta cctgaattgg caattcaatc ggtgaatttg
    78781 cgtacagcag caaatcaaaa tcactggttt cttttactgc cggaatccca gtcgataatt
    78841 caaatcctaa gctgccgccg attccccatt tacatcctga taatatgttt ctagcagcat
    78901 gaaattgctg ataaacagga taatccatga ttttctcttg tctatacgat tcttgttcga
    78961 tgatgtccca cggatgaatg acttgtttga cggcatgttt tgagatttct gttgaccatc
    79021 tctgattgcg ggcaggtcca cgtaaaccaa tcggtagtat ttctgcgtga tccgtcgacg
    79081 cacgacgaac tgttccgaac atcttttcag ttagaacgac ccattcaggc aaggtgaacc
    79141 cttctatttc atgtttatca aaaaggacaa tatcatgtgc ttgaatcatt ttttatgcat
    79201 cccattcttc gtccattttg gcacggactt tatttgtttc gacacgtccg aatgttttgg
    79261 ctgtttcgtt tgtgtatcga tttgtcagca tcgtgtcatt tgtattgcgg acatcttgaa
    79321 tggcttcatt gattgcttcg atgactttgc tgacattttg ttctgaagca gcttggtcgg
    79381 tgatatcttc taggaaatga tagatcgctc ctagttttgt ataattattg atatcgtaag
    79441 cgatagctgg aactttttca gcagctgctt cgatttcagc aaccgaacgt tttgtcacac
    79501 gtgcagcact ttctttagac atcgcttgga cggtaatttc tttattgttt aaagcaatca
    79561 agcggcttga ttgtaatcca tgtgctaaaa atgcacctga aatagcattt cctgcaatca
    79621 atccaataac tggatgtcca gcttgacgga gttttgcata agcagcagca ctattagcca
    79681 aagccacatg gataccgatc aattcttcgt tatagccgta tgcttggctt ggtacatcga
    79741 tcacaacgat gattggccgt ttcacttttt tgtctttatc ttcttcgtaa acgtgatcca
    79801 aaatttgtcc catgcggaaa ccttcaacta aaccaacttc accgtttcgt acacggtaca
    79861 tcgggttttt aggatcaggt acgattgatg tcacgatggc ttcttctatg aatttacttg
    79921 atttaccata atacacagta ctaatagaag aagttggatt tttcatgcca gttagtgccg
    79981 caaaccaatc gtaaccaaca cttgctgcag ctggttcatt tccttctgct acttctggta
    80041 agtcaattga ttttgcttga tggttagcaa ttgcttcatt gtaatcgtca atggccattg
    80101 gttttgaaag atctaaagaa tcaagtaatg ataaataaaa tgctgagctt tcactgcgat
    80161 gcgtgtcttt tcgttcgtcc attgctgcga tgacagcagc tttgattgct tctacactat
    80221 cagtcactaa ttcatcaatg atttttgatt ctacccgttg acgagatcct aatgtattcc
    80281 aaatcaagtc tttgtcacta gaatcaaatt ctcgaacgcc tgcttcttgt tcaataactt
    80341 ctggtccatt caaaccgact ctcgcttttt ttgttgcgat taaataactc attaatgctg
    80401 aagtaatcga cataccgcca aatgatccta cacgtcctgg aatcaaaccg atgactggta
    80461 catattgttt tagagcaatg attacatttc cgatttctga aatagataac agtccgtagt
    80521 ttgcttcttg caaacgaaca ccacctgtat ctagtacaat gactggaaag atctcatttc
    80581 cttttttatt ttcttctaac acatgttcaa gtgcagcaac gatttttgca ccggaaactt
    80641 caccgatacc gccaccttgg aattttcctt ccatagcgat tactactgct tgtttgccat
    80701 tgatcgtgcc acggctgaca acgatcccgt catcactttc agggacgatt ccttgtgctg
    80761 gtaaacttgg cgcgatgatt tgatcgaatg gatcaatcaa ttcacgtcca ttgtcaagta
    80821 gagcgttcac tcgttctctg gcgtttaatt ctacaaaact atttttcatc tgaaagttcc
    80881 tccattgctt gcgtcaatcg taggtacaca actcctggtg tagcaccgaa gtcattgatc
    80941 acgatatctg ctgaaattgg ataacgatca aaaaatctcg ttaatacatt gttccatact
    81001 tcgccgaagc catcgcttcc tgtacaaatt tttacagtag attctgtttt ttctgttgga
    81061 aacatcaaga tttccaaatc tcctgaaccg accactccta catggatttt cttattgatc
    81121 ggctgtttcg ttggatattt ataagctaat tgttccatgg atctctcccc tttttgtaaa
    81181 acagagcata cacgttctgc ttattcgtct ttcttcttcc atctgggtaa atggcgacaa
    81241 aaggtttttc tcgccaattt tatgaccaag ttctgaattt cattggtggt tcatacaggc
    81301 catctgacca ttcgatcaaa tcatcgatgg tttgtgcagc taataatgaa cgtttcgctt
    81361 cactacgttt gatgcctaga tcttctggta atttcacgat gccggctgca cgcaagctat
    81421 ctagtgattc tttcgtgcta gtcattccaa gaggtgtaac accgccaatt gctgcaattg
    81481 ctgcttgtcg ttcttctttt gtttttgctt tgtacaaata agcaattcct tcttctgtca
    81541 cgatatgtgt agtatcttcg ctataaatca tcactggtgc attggctaag cctgcttgtt
    81601 tttgaacagc tagtgcatct aattcttcga caaagactgg ttttttattt gaaccatatg
    81661 tttcaaccat ttgaacaact aatttttggc ctttccctaa tggatcatca ttgtcgcgaa
    81721 gtgattgcca tgctggtgta gaatgacgac gaccgccagg attatgtccc atgttaggcg
    81781 caccgccaaa accagataaa cgtccttttg ttacggtaga agagtttcct tcgtaatcta
    81841 attgcaaggt tgaaccgata aacatatcga tggcatattg tcctgcagct tgtgataatg
    81901 ttcggttact gcgcatcgtg ccgtctttac cgacaaaaaa gacatctggg cgagcagcaa
    81961 tatatttttc cataccaact tcgccaccaa aactatggat gctttcaacc caacctgatt
    82021 cgatggctgg aatcatcgtt ggatgtgggt tcaataccca gttcttcgcg attttccctt
    82081 ttaaccctag tgattcacca taagttggca gtaacaattc gatagctgct gtattgaatc
    82141 caataccgtg attcaaagat tgtacgccgt gttctgcgta gattcctttg attgccatca
    82201 ttgccattag aatttgcaat tctgtgatgt tttgaggatc tcgtgtgaat aaagcttcta
    82261 attgataagg tttatctgct ttcacgacaa cgtctaccca gtcaccaggg atatctacac
    82321 gtggtaaaga atcgacaact tcgttgactt gaacgatcac gataccatct ttgaaagctg
    82381 cagcttcgat gattgttggt gtttcttccg tattgaaacc tgtgtacaag ttgccgtctt
    82441 tatctgcttt atctgcagct actaaaacaa catttggaat caaatcgatg aataagcgtc
    82501 cataaagttc caaataagta tggatatcac ctaatttcat tgtgccgtct tcaatcattt
    82561 gggcgacacg caagctttgt gcaccagcat aagagaaatc gatcttgctt gcgattcctt
    82621 tttcaaaaat attcaaatgt tctggtcgtg agatactaga catgatcaaa tgcagatcat
    82681 tcactttttc tgcatctact ttttcaagac tttctgaaag aaaacttgct tgtttttgat
    82741 tgtcgccttc taatacaact ttgtcgccgg gagcaatcag tttttccatt acttctacga
    82801 ttttttcagt ttctacatac ttgccattga gcaagttgct gattttttcc aatcgctgcg
    82861 cttttttttc gcgtttagaa gcccagttgc ggtttggttt ttccataatt agtcatctcc
    82921 atttttgata tagaaacgtg gcgtcatcaa taccatgttg gtctagattg atcgtacgga
    82981 tccctttatc tacaccaaat tttgtatgaa tcagctttgt caaagtattg ccggggggaa
    83041 attcaatcgt cagatccatt cctaattctt ttgccaagtc catcatttgg ttccactgca
    83101 cagggaaagc taggttttcc aacaaatctt tacgaatctc ttctgcgtcc tgagtggctc
    83161 ttccatccgt attttttata tacaaacatc tagcatcaga tagatggaca gactgcatat
    83221 acggcttgaa tttcttgacc gtatcattca tcaagagaca gtgagatggc acagggactt
    83281 tcagcagctt cgctgtttgc gcttggtgcc gtttggcttc tgccaacgta acggataaac
    83341 cttcgatact cccagataac gtatgttgca tcggacaatt ttcatttgac agataaactg
    83401 gatggtcagg atcaaatgtt tttgctacaa tttcctcagc ttcgcttctc gtcacaccta
    83461 ctactacgcc cattgcataa ccgcttggat aagcttcttt cattaagact gcgcggtgat
    83521 agactagttc cgctgcattc tcaaatctca aagatcgaca agcaacagct gcacaaaaag
    83581 caccaatcga atgtcctgct gcaatatcag gctgaatacc gtttttttcc atttcatcta
    83641 aataaaatac tgcttttgtc agtaatgcta gctggataaa aaccgtatct tgatagtttt
    83701 cttctttatc aactaaccga taccccgtca cattttctaa acgttccatg tacatttcag
    83761 ggatatccgc taacatccct aacttctgac tgccttgtcc aggaaataag aaacctgtac
    83821 tcatgagcct cgcctcctca gcacttactt tttccactgc tatcttagtc aatttctgct
    83881 ataataaaaa atgccaaaaa aagaaaaaac cataacaaaa aggtatggat gggatggata
    83941 attatgaaat tgcttcatct gcagtatttt aaaaaagtat tcgaaacaaa aaatgttacc
    84001 caagcagcca aagaattatt tatttctcaa cctgccttga gccgtgcgat caaacatttg
    84061 gaaaacgaat taggtgtccc tttgttttac catagcggca gaaacattga gacgaccgtt
    84121 tatgcagaag aattttatcc atatgcagtc aagacattag acacattaga agaaggaatc
    84181 aaattattgt cttcggtcaa tgagaagatc gttacttccg tcatattgta tttagaggta
    84241 gcctctgttt ctattccgaa cttggtccga atttttatgg aaaagcatcc tgatatccaa
    84301 ttaacgatca tgcaacatca tttaccagat gatattaccg atcctgtact gtacatcact
    84361 tcggagatga agcctggcat gaccaatatt cctatcatga aagaacctgt ttatgtcgcc
    84421 attcctaaga aacatcctct tgctaaaaaa gaacatctgc aattagaaga tatccaacgc
    84481 acccccatct tgatgctgtc aaagagcaac gccttccgtc atacactgga tgcagcactt
    84541 gaagcgaaaa gtatcgaatt gacgatcagt tcgacgacag atgatcctgc gacattacgt
    84601 tctattgtca agcaaggatt agctgttagc tttttcccaa aagtttcttg gtcttacgat
    84661 aaaaatgatc ctttcgtctt gcgggaaatc aaagatttgc ccttgacacg aacaatttat
    84721 ttatcttcta gcttcacaga agatcatcct ttgatcaaaa tgattgcaaa aacgatgcgg
    84781 gaattttatt taggaaaata aaaaaaaaag agctgggaca aaattcttgt cgcagctctt
    84841 ttttcgaaca aacggtgttc cagaagtaat ttcttagaaa ataagccgaa atttcccaaa
    84901 aatttgagaa gcaattttcg taaattcctt cttatttctt gaagctaaac atttctgtca
    84961 caacctcttc tctattgtcc tagacattca ttgcgttgat ttaaaacttc catcaatcaa
    85021 atctgctagt tcatctagct tttctatttt acgtagatca atagagatcc aatgttcttt
    85081 attcatgtga taggctggaa aatacccctc ttttcctcgc aaaattccgc caagttcagg
    85141 atcgaccttc aaatcaagaa tattgatgat cctatggtca cttgcatcat catagatttt
    85201 ttcttctgga acagacatca ggaccccaaa ccattttttg cttttttgat gtctgaatac
    85261 gcaataatca ggaaattttt taaaaatata ttctggagac aaattgtatg tttcattgat
    85321 gtgatcgatt agttcttttt tcgttagcat ctgcttccat ctctttctta ttgattcgct
    85381 ttattcaaag ataccacgta agaatagaaa aatgaataca agtagttgct aatcaaatac
    85441 ttcgatattt ttctttttta tcaactctta aatgttcaat ccgcctgtgt tggtcttgct
    85501 accatctact attaaaatgt ttattattgt ttgcccacct attttttgat tttagtggta
    85561 tcatttttca agttcatgat gaaattctta tcatcagtaa atgctccaga aaaataaaca
    85621 atgattgaaa aatcagttga aacttgacca ccgtttattt tctccgtatt cttagaatag
    85681 aagggagtct gattgatgta ttcactaatg aaaaaaatca ttaccgaaaa agatattcga
    85741 cgtcatgttt ctttagtaga acaattgctg aatcatacaa agataaccgt aaatgaatta
    85801 gctgaaatca tagggacaac cgaacgaacg attttttctg accttcaatc tattcgctct
    85861 cagctgcccg aaggctggga catcatcagc gatcaagcag gaatcagttt gcaaaaccag
    85921 caaaatttat taacaaatga cctttgggag atttttttca aacaatcagt cagtgtcgaa
    85981 ctgctgaaaa atctgctttt tacaaaaaaa gttgctgtcc ctgattttct agccgaccat
    86041 gggctttctt atgggacatt gaaaagacat gtgactaaaa tcaatcagcg tttagcaagt
    86101 tacgacttgc agatcgattt gacgaaatat acagcttgta ttcttggaaa agagcgtgcg
    86161 attcgtactt tttatcatcg attgctgatt cctttcactc ataacaacta ttttttcgag
    86221 gattattcga tccatgaatc ccattatttt caatttttaa gaaacctcag tcaaactgaa
    86281 ctagcggttg aaacagaaga gattttcgga acatgttggt tctttatcaa tacgatccgt
    86341 ataaaagcga attgccgatt agattcttct atccatacca acagcacact ctcctccctg
    86401 tatgactctg cattgaaaaa attgtattta acggaaggta tttatcttaa agacactgag
    86461 ctttcttttg cttctttctg ctttctggaa agttggaatt acaacaataa ctatggacaa
    86521 gaaaccgctc gctgcctgca tcattctcca tttttagagg tcctcgaaac gtttgtagag
    86581 gaactagctt cagagctgtc tcttgatcaa ctaaaaaaaa catctctgac tgataacttg
    86641 gctctcctca tattaaaata tcatgaatcg ccgatattga ttgaagcatt ggaccgtcaa
    86701 taccatcgtt ttttagaaac atatgatcag caatatgcac acttgtatca acagaaagag
    86761 aatttactga acgatctaaa aaaagaaata gaaatcaatg aaccaaatta ctttctccaa
    86821 ctcttgtctc tactgatcca acaaacgatt ttttctatca aaccgaattt gttcaatgtc
    86881 tattttattt tccaaggaga accttcatgg aaggcgttct tgcagcagga attaaaagat
    86941 tacttaggaa aacgtgtctg cttcttacct atcgaactaa ccgatctttc cactatttct
    87001 tttgaaaaaa cagatatctt gatttccaat ttccctctag attctctaga tatccctatt
    87061 gtatacattt cttctattcc aacgaaaaat gagctcaatc gtttgactga actcactttc
    87121 aaaacttttt tatagtaacg gctagcgact gtattctcta gctgtttttt cttttttgcg
    87181 aaacagtttg ttcatgatcc ctttttctat ttctacaact aagaatagaa gaatcacatt
    87241 tgctccaatc aataactgtt gtgtcatcgt taaacttact gtaccgatca gctgctggcc
    87301 gactggtaga aaaataacca tcccttgcaa taaagcaagg atacctaatg aaagaaaaag
    87361 cgctttgttt tgcaaaagac cttggttcaa tgacggcttg gacaactctc tgcaattgat
    87421 catgtaaaca gcttgagcta agacgatatt ttgcagaaga atggtttgct gtaagctttg
    87481 cccttcaaac tgcatagcca ataaataggc aggaaccatg atcagtaggg agacatagat
    87541 gatccgaaac aaatgataac cagataggat tccttgcttt ggatctcttg gtgggcgctt
    87601 catgatttct ggatctggcg actcgaaccc tagtgcataa gataaagtga ttgtcgttac
    87661 catattgacc cataaaatct gtactgggga caaaggtagc gggcgattca gcataagtgc
    87721 ccaaatcaag atcaatcctt gagctaatgc agttggcaag aagaaattga tggttttttg
    87781 caaattatcc aaaatccgcc ggccctcttt tacggctttt gcaatcgtat ggaaattatc
    87841 atctcctaaa accatatcag ctgcctgttt gcttacttca ctacctttga ttcccatagc
    87901 aattcctaca tcggatcttt tcaaagcagg tgcatcattt acgccgtctc cggtcattcc
    87961 gacgatttct ccatttttct gcaaagcttt aacaattcgc agtttatgtt ctggtgtcgt
    88021 tcgagcaaag acatcgacta ttggcacttg ctgaatcaac tcttcatcag acataagatc
    88081 caaatcgatc ccttctaaaa ctttggcagt atgttttaag ccaatttgtt ccgcaatcgc
    88141 ttttgctgtg tctttgtgat cccctgtaat cattttcact gagatccctg cttgttggca
    88201 ttcctttaca gctttgactg cactttcttt tggcggatcg atcaatccgg cgatccctgc
    88261 aaaagttaat tgggttaaag tctcatgcgt gagttcctgt ttcgaatcta cttttttata
    88321 agcaaatcct aaaacacgct gaccttttct cgcaaattct gcagctgtct gactccatgc
    88381 ttcttgttct gcagaagaaa gagttgattt agcaaataat acttctggtg cacctttgac
    88441 gtaaatcacc gctccttttt cctccgcatg catcgttgcc atatatttgt attcagaact
    88501 gaacggaatc tttgcttcta tttttttcaa aggtagattg gctgtttctg tgtgtcgaat
    88561 cagcgcaact tctgtcggat tgccacttaa attttctgtt ttctgttctt cttttgtttt
    88621 taattcctga cagtttttca taatggacaa cacgcaggct tcttcttttg cagctacatc
    88681 cacaactgtc atttcatttt ttgtcaatgt tcctgtctta tctgaacaga tcactgtcat
    88741 agaacctaat gtttctaccg aaggaagtcc tttgatgatc gccttttctt ttgccatttc
    88801 atgtactcca acggatagaa tcatggtcaa aacagctggc aatccttcgg gtaccattga
    88861 caccaccaaa gcaatcgtag ccgaaagaag gatatgccaa tccataccat atcgaaatgt
    88921 cgtaaaaata actaagaata ggctcaaaca aagaatgcct tgaaaaattt gtttgtttaa
    88981 tcggttgatt tttttaatca gaggcgtcgt ttgttgttcg accgattgca atgcttgatt
    89041 gattttaccg atttctgtcg tgtttcctgt ttctacaacg acaccgactg cagaaccaga
    89101 ttgtacaagc gttcctgaaa aacccatatt tttctggtcg ccgatcgatt cttcttctgt
    89161 caaaacggca tgactttttt cagatgcttc tgattctccc gtcaaaatcg attcttccac
    89221 taataaatca tgtgcttcga ttaatcggat atctgctgga acgacatctc cggcacgtaa
    89281 gacaatgaca tctcctttta ccagttcttt cgcagggatt ttttcttgca tcccgtttga
    89341 tagtactatc gcttcttgtc ccatcagctg cttcaaacca ttcaatgatt cttccgcttt
    89401 tctttcttgc cagtaactaa cgagtccatt gacgatcact acgaataaaa taatacttcc
    89461 ttcaatatat tcactagaag caaatttcaa aaaagaggca atgatcaaca cgatcatcag
    89521 cagatcagta aaatgctttg ctattttttt ccatcgtttt gtctgctgcc ttgcttttat
    89581 ttcattatat ccttgatcag tcaggcgttt ctgtcgttct tcttgcgaca agccttctgt
    89641 tgatgtttga tagtttttca atacatcttc taccgtcaat ctgtaccagt tcatcctatc
    89701 ccctcctgtt taattgatac tgttattata cgcagggaag ttttttcagg cgtatcgatt
    89761 atttcagggg ggtctgaaat aattcgtttt gcaaaatgta tctgggccta actgatattt
    89821 ctattgctta ttcttttata tacaaaattt aagaatacaa accagataac caataaaaaa
    89881 ggaataaagc gtgtcgtgct ttcgaataac aagctgaaag caattgaagt aaaaaacacc
    89941 aacaaagcaa gatctttata tctttgtgta gtgttccgtt tcttttcttt aataaattga
    90001 acatgtgcac acaagatcga agaccacaca aatagaaaac aactcgttgt catgcctgcc
    90061 aaaagctgaa aaaacaatcg actatcagct acaaaaaaat gtagacaaag accggcaaaa
    90121 aataacattc ctgtaattaa aataccgtgt aaaggtacgc ctttcttaga aagcgcacaa
    90181 aaccaatggg gcaaactttt ttcttttgct gtttgatata aaatcctgct agtactgtag
    90241 actgcactat ttgctgagga caaagaagca accaaaatca ttagattgac aattgctgct
    90301 ccgccttggc aatggatcac ttgcagcata gtcactaaag gactttcttt taaatctaaa
    90361 caatgccatg gaacaacaaa taaaatcgac aaaatcgttc ctatatagaa aaagagaata
    90421 cgccaaggca gacagttgat tgcttttttc aaattctttt gcggatcact tgtctcgcca
    90481 acggttaagc cgatcatttc aattccagca aaactgaata aaaccatagg aaatgagact
    90541 accattccag caaagccaaa cggtagtaat tcatcgatct gtccaaaatt ttctttgatt
    90601 ccgatagact gggtatgaaa atctgagaca ctcaatccta tacccaataa gataaaaagg
    90661 aaaatcccca agatcttgat gattgagaaa aaagattcca attcaccaaa ccacttgact
    90721 gcaacaaggt tgactgccat taagatcatt agtgcgctac ctccgcttat caaagctggt
    90781 acatgtacaa accagaaatg gatatacaat cctattgctg ttaattccgc aagtccagct
    90841 ccaagccagc aaagccaata agtccaattg acaaaaaatg cccacttttt gcctaaataa
    90901 tagtcaacga aatcactgat agagttaaat gtactatttg ctaaaaataa atcacccatg
    90961 gcccgcatca aaccataaat agccaaaccg catatcaaat aaacgagaat aacagctggc
    91021 cctgctgatg caattgcctt tgctgaacct aaaaataatc ctgttccaat tgcgccacct
    91081 aatgcgatta actggatatt tcgattagtt agagtccgtt tcattgccgg tttttccatc
    91141 aagttcacct ttttcttttt caagcagcat ggcgacttcc tgttcccaag aaggtttctt
    91201 tattttttca atacagagtg gtactacaaa caaaatgaca ctgatggctg tgactgcaat
    91261 tagattgatc catgttccag ctttcatcgt cagtccgaca gaaaatccga ttgccgcaaa
    91321 taaaacaata acgacagtcc aaactccaag attgctcttt ttctcttttt ttccaattct
    91381 aaatggtcga ttcaactttg catgtgtata acgcaatctc aaaactgcga tccccatgat
    91441 gacatagacg atacagtaga taacagtagt tgaatttacg agcatcaaaa atgcttgatt
    91501 gacgccagga atcagcaaat aaaaaagtgc aaagattgag ataatgacag actgagtcaa
    91561 aataacggat ttggatacgt caaattgatt cgtcttccaa aaattgaatt ttggtggata
    91621 cgcacctttt ctagcacttt ctgtcactgt ctttgctggt cctgaggccc aagcagataa
    91681 ttggactgct acaccaatga agacaagtaa actaaacaga ttcacaataa gatgtggcaa
    91741 accaagaatt tggcaataaa tcgaaataga ttgcgcgata ttattcaatt ccatttgtcc
    91801 ttttggtacg acatttgcta caactaaagc attcaaaata ttgacgaaaa atataaaaat
    91861 taacgcggca aatactccgc gaatatacgt tttaactgga ttttccaatc gagtgatata
    91921 cacagaggac atttcgatac cagtaaaaat aaacatgatc ggcgcaaaat aaacaaatga
    91981 ggatgcagtc gtagtatctg gtattaattt gtcccatgaa aaactgccta atgttccggt
    92041 tggtacgatc ccaactttga tccacgcagc aaaccctaat aagagcatca tcgtcaaagg
    92101 cacgtacaat cctaaccaaa caccgacttt tccgccgatt tttgccatat caaatttcaa
    92161 attcaaaaaa gtgatgatcc aataaacgac taaaatgaca actaatgtaa atttgctgtt
    92221 caaaccaagc ggcacattat cgataatatt accaaacaac ggagcgagtg ctgaagcgac
    92281 catcaccatc ccaggaaaca tttggaccca taacagccat gagacaacga acccccattt
    92341 ttttcctaga gcattcgata cccaaagttc tggaccacct ttttggggaa acattccagc
    92401 aaattcacca gagatcaatg agattggaaa agcgtacaat aatactgcaa ccagcatgta
    92461 aaaaatcatc gtccagctcg ttgctgctac atctggaata tttcgtacac ttgctacaag
    92521 ggcgcaggtc attccgataa aggtcatggt cgtgatttgc tttgatgaac cagtatcttt
    92581 catctttatt ccttctttca atagcgacat atgtttttgt tttcttttat ttttgttcaa
    92641 gaacagaaat gacaaggttt catcgattca gtacaaaacc cagtatcacc gaaacatcca
    92701 ttgaacgatc ttagtgaact gggtttgata catgaaacga acgatccaac ttatagaacg
    92761 ttttataaaa aagaatatct tggcgaggaa tatatgaaaa acagggggaa atacaattgt
    92821 tttgatgaag caaataattg tctgttctcc atatgtctct tgttattctt tcacacaaaa
    92881 atcagttcta ttggatgatt tcgtttagtt tcttttccat tgctttggcg attttttttg
    92941 tataaaaatt gaaaattcga tcatcattca aataaggagt catgatagcc gcacgtagca
    93001 gagtgatttt ctgttctttt ttccattctt ctttcgttag acccattctt tcaacaaaac
    93061 gaatcggaga atcaccgtaa tcttcttgtg taaatgtagt atgagaagta ataaaccgtt
    93121 caccataaac atcgccatcc atataagaag accgatcgaa cattttttca tttaattcat
    93181 tgatagcgtt caaatctgta cagccttgtt ctttgaatac ccaattgacc atattaaaat
    93241 caggatgatt caatggatag acttcgattg tttttccttt aacagtaaaa gtcagatgat
    93301 cgagaaattc tctgaatctt tgagctgcct cgattgaagc cccaatcaat tgaccatatc
    93361 cggtcacatt caatggcaat acacgatgtg ctgtccagac tgcggcggcg gttgctccag
    93421 cttttgatcc ttccaaaata taagctccta acatatctgg agcctttact gatttttcaa
    93481 acacatatgg cgcgaaataa gaaatgatat ttctcatatt tttatgtttg attacgattc
    93541 ctccagcagc ataagggaca tagcccatct tatgaggatc tatcgtgaca gaatccgctt
    93601 ctgaaatagc tctgaaccct tcatatacct ctttgtcaat cgttacgcag tggtggaaaa
    93661 catgatgttc ttcaaagaat tcagctaagg aagcatacgg cacaaattct cctgcttcgt
    93721 ttagaaacag tgaacgcgca tagccgccat atgcggcatc aacatgtaaa tagaaataga
    93781 tcccttcatc ttttaacctt tctcttaatt ggacgatttt atctacactg tctacttgac
    93841 cttcttctgt cgttcctacg acagcaacca cacctagaat tgggattttt tgtccagcta
    93901 attcacgaat tgttttttcc aaagcattaa tatccattcg ataatcctct tgaactggga
    93961 tagcaaccat ctgatctaag ccgactccgc aaatatctaa cgccttcatc caagaatagt
    94021 gttttgtttg agggaccagc catttcccta atctttggat attttttccg ctacgggaag
    94081 aagctgcttt gacctcatcc atttcttcgt ccgtaaagct ttcggtcatt tccaaaattt
    94141 cttcaacaga taaattcaaa agttcccact cagacatttt tttcactttt tcaggcagca
    94201 cttccttgac agctaaagga atcgatttga tgcaacgggc gtaccataat ccttcaagat
    94261 tagcaataga accatctgct gcaatgtgtc cccatccgtc tgtcatattg aataatgaag
    94321 caaaatcctg tcctacttct gcttccattt gcgaagttgc catagaagat tccaatgcaa
    94381 cattatttgg gttccacagc atcgcatagt tgtaagctaa taaagcaggc atcaatgttt
    94441 cagcattcat ttgtccccag taacggcctg ctgaatgcca tgggatcgat cctgcgcgta
    94501 atcgctgact gacttcatcc aagacctcta tcatatggtc gcgggtggct agataatctg
    94561 gagtgagctt atctccttcg ctaattgcag gcatatctga aggaatataa ttttctctcc
    94621 atccaagatg ttcatctacc atcttgttca acaacatttt ataaactggt ccattttcag
    94681 ctttgtcgcc tataaagacg gccttgatat ccatatcttt catttttctt ccctccatat
    94741 tttgttggtc aatgtcttgc agatacatgt gtttatctgt aacacctctt cactatagcg
    94801 ccaaaaatga gaattttttt tttataacat caaatccacg tagattttta caaacaaaaa
    94861 taaataaagt cggatttttc tgataattca acgcaaaaaa gcgaacaatt tttcaataaa
    94921 tcagtcttct aaaatagata acctaaaaaa agcgaacaaa caaataaaat gactgccctt
    94981 cattcactaa acatattttt atttttttat attgttaaaa attcgcaatt tattttttaa
    95041 tagaattatc tgttttccaa attttataac ataaaaaacc ttttttaacg gcatttatat
    95101 gctttttcag aaattaactg atgatttcaa aaagaaaaca tgtcataata tttcccatat
    95161 tgtgcaaaaa aatacaaggc ggaggctcta ctatgattga agaatatatt gagaaaaata
    95221 ttttaagaca gctgttttta tgtgggcaat tctatgtaaa taaagaagtc aatctagaaa
    95281 agctctccaa tctcctgcat gtttgcaaaa ccactttact caatgatatc aataacataa
    95341 aaaaagaatt tgaagaacag atcgcttata cacatcggga aaaggaccgt tacactttat
    95401 atttttcaga acatatacct cgatgcaaga tcatgcagca attgtctcaa aattcgttgt
    95461 ttttaaaaac ttgtctgctt tatttggaag aagatgaacc tgattatctt caattaactg
    95521 aatgtgaatt catctctgtc agcaaagctt attcattaaa aaaacaagta ttagcttatt
    95581 ttaatgactg cgggatcgaa atcgaccgct actcccctcg attcactgaa atggaaagac
    95641 gtctgctgct tcttaatgtg tcgtatcgtt taggcggttt taattcttgg gagctacctg
    95701 aatcgttttt tgaacgtgcc gatcgtttca ttgaatccgt aacggaaaat agtggcagat
    95761 tttatgataa agaaaataaa gaaatcttat cgattggttt tgctatcagt ttcctacgcc
    95821 agcaagtgtg tgctgtgaca atagattcaa aatttatcga agaaatcaaa aaacgtccta
    95881 tttacaatta tgtcgaatca gcatgggaaa acactgattt ccaaacctat tataaaaaag
    95941 aagaattcgc ctttattttg acactattca atctttgtaa ttatggtttc cattcttatc
    96001 agttgattgc ggaagacttt caacagctac accaagtgtt tattgacaat actcccgaaa
    96061 taaaagaact agttgctacc tttgaatctc acttcaatca agaattattc ggaaaccaac
    96121 cgttcgaacg tgcgctgatt catctgatgc gttcggcttg ggataactat caattattca
    96181 tgccagaaaa attttatctt ttaaatgagg aacagacaaa tttatataaa gaagtccaga
    96241 caattttttc cagctggtcc agccagttac cttatgatct acggttgaat cctaattgca
    96301 tgcgggcttt tgtgatcgaa ttgagcggaa ttctccgtct gacaaaagaa catctgacta
    96361 tctatatcgt cacaaattcg gatgttcatt atctgattta tcgggaagcc ttggaagctg
    96421 taactacttt cgattttcaa gttgcaccaa caatttattc aagtatatct gatataaaga
    96481 agtatgcgca gcagtcctca aaccgggtat tatgtgaacg tacattatat acaccagatg
    96541 cggtccaata tgaaaatatt attcctattt cgatcaatac gatcgatcga gctatcattt
    96601 cagctgtgca aaacaaataa ggggctgtga caaaaatcat gtcacagcct cttatttgtt
    96661 gaagatgccc atttctgtaa caatctcttg atacacgtca ggctcacaac ctcacttatt
    96721 ttggacatct acgggtccga tctctttatt taaaaaataa gaaatgatgg ttcggataac
    96781 taccaacgcc gctagttgga aaatatcctg caaggtaggt ttgataatcg attcgatgat
    96841 cccagctgaa acaagaattt ccaaacttag aagtatatag cctcccaaca tctttttaat
    96901 agcattgttc tcgctgactc ggtcgctttg cacttttgta tggacaaata aatatttcaa
    96961 aaaatccttg attgatagac aaacacccca aaccaataaa cagatagcaa agatatcaag
    97021 tcccagtaca agtttttcga aatatggaag aagaaactgc atcaactctg tcgtcatcct
    97081 acctctcctc ttctttgttt ttctttgtct tctatttcct gattcaagaa ataagaaatg
    97141 actgttcgaa tgataataat aagtgcaagc ttcaaaatat ctgtccaagt cggcttgata
    97201 actgactcga tgatatcagc aacgactagt acttccaagc ttaacaaaat ataacttgct
    97261 agcagttttc ttgtatctgc attacgagta ttacgttctg catagttttt cttgacatga
    97321 gaccaatcaa aaagtttgaa tagaacaaga acgatcccga caattaagat accgatagaa
    97381 caaatattta aaatagcaat gatccattct agaaattcaa ttaaatttga gcgaaacata
    97441 tacgctacct actttctttt aatttgttcc tattctttta ttgtaaaaga aagttacctt
    97501 gttcgtctat ttaaaagttg ttctaatgat aacggttcgc ttaaattttt ctttttcact
    97561 ctcccatttt tctccctcca tccataaatc gtggaagtat ccaaaacaac gtagcaagtt
    97621 aaaataaggc ttagtccgtc atcagctttt caaagaagca ctgtctcggt gctttttttg
    97681 tacccaaatt tctaaaaata gaaccataca cctcctcaaa tcttttcttc ttacctaccc
    97741 tatttttatt tacaggaaaa tcagacactt cttctttttt gtcaaaattt cctttttctt
    97801 ctcgtcctat catttggcat tctaataaaa acgaactatc cttggatata gaaagagaaa
    97861 acaaggaggc gtttttcatg agtaaaaaat taatcaaagt cggcatcggt ttaggtttgc
    97921 ttgcccttgg cgctgcatat ctaggaaaaa agacaggact attcgaagat gacagtcatt
    97981 tatatgatga attcgaatca atctagcatc ctatttagtt gaatcactac ggacatactt
    98041 ggaagacatt ggaggaatca caatgagaaa aagtaaagca ataatgattg gtgccggtat
    98101 tgccaatatg gcagcggctg tttatttgat tcaagaaggc aaatggaaag gggatcagat
    98161 caccttttat tcattggatg atcacggttc aaatgatggt gcaccgaccg acactgtagt
    98221 ggatgaatat tggaataaaa accatccatt agaaaaccaa aaaggctata ttgctcgagg
    98281 cggtcgcatg cttaattacc gtacctatgt agatttgatg gatctgttaa gtcgaatacc
    98341 ttctgttact gagccaggga tgactgctga agaagatacg agagattttg atgcaaaaca
    98401 ccgaaccttt gacaaagcac gtttgatgga aggtggcaaa ggaatcattg atggcggaaa
    98461 actgggattc aataataaag accgtattct tctgactaaa ctgattgcta tgcctgattc
    98521 agaagaagaa aaactagaca atatcactat cgaagaatat ttcaaagatg atccacactt
    98581 ttttgaaaca aacttctggt ttatgtggga aacaacattt gctttcagaa cacgtagttc
    98641 tgctcaagaa ttgcgtcgct atatgcatca aatgatttat gaattcactc aaatcgaaca
    98701 tctagtgggc gtcaatcgaa cacgttacaa tcaatacgaa agtattatgc ttcctttgat
    98761 cgagtacttg aaagaacaag gatgcaaaat cattttgaac cgccgtgtca ctgactggga
    98821 attcaaagaa acaccgatgc aagatgaaat cactgtgact ggtttgaaaa ttaccaatac
    98881 actgactcaa gaagaagaat acgttgtggt cgatgaagat acagcagtta ttttcactaa
    98941 tgggtccatt acagattcag ctactttagg agattacgaa acaccagctg tagaaaatat
    99001 ggattatggt gcagcttcta gtctctggaa aaaagccagt gaacgtttct acaacttggg
    99061 aaatcctgac aaattctttg ctgatcgaga tgcaagcgaa tgggtcagct ttaccctgac
    99121 gacgaaaaac catttgttgt tgaatgaaat cacccgtatc acgactcaag aaccaggaaa
    99181 tgccttgaat tcatttattt caaccacacc gatcacgccg ttaggccaaa aagatgtcaa
    99241 tatgtctatc gtcgtgcatc atcaaccgca ttttacgtct cagaaaccaa atgaaacagt
    99301 tatttggggt tatttccttt atccaagacg acgtggcgaa tttgtggata aacagtatat
    99361 taaaatgaat ggaaaagaaa tgctagaaga actgattgga caactttcaa aagtagatcc
    99421 tggaccagtg aatattcgtg aaaaagaaac agaaattttc gacagcgtaa taaataatat
    99481 ccctgtctat atgccttatg cttccgcgtt gttcaataat cgtgccaaaa gcgatcgacc
    99541 aaaagtcatt cctaaacatt cgaccaatct ggcctttaca ggagaatttg tcgagcagcc
    99601 ttatcagatg atctttactg aacaaagtgc tgtacgttct ggagaaatcg ctgctttcca
    99661 ttttgcgggt attcctatgt cccgtcttgt caaaacaccg cgttacgaca aagatattcc
    99721 tactctagct cgtgccgcaa aaaaaatgtt tgaataatca agaggttgtg aaaaagctgc
    99781 cctgcatcaa gtaataagaa cacccaagct aaaactgctt cttatgtttt tgacttggtt
    99841 ggacttatta ccgcagatgc aagcttttga acaccattta ccaagaggtt atgaaaaagc
    99901 tgccctgcat caagtaataa gagcagccaa gctaaaacag cttcttatgt ttttgacttg
    99961 gttagactta ttaccgcaga tgcaagcttt tgaacaccgt ttaccaagag gttatgaaaa
   100021 aggcgtttag tttcgagtat gaagaaaaat tttgtgaaaa tggttcctca cgtttttgca
   100081 taaatttgac ttaataccga gaaactgatc ccttctgtca taacctcttt ttatttatgt
   100141 ctgtttcttt ttgaaaacaa ctattttttc aacgtttact ctcttgccaa tccaacatca
   100201 tctaacggat acaactattt caatgattac cattacacta aaaaatcgga aacacacctc
   100261 tccgaacaca aatacataag actatagaat gtttcattta agaaaaaaag cgtttcatta
   100321 tcaaaaaggt aagatctcct ttaaaatgaa attatctgta gtactaataa tgcagacaat
   100381 tttatgaatc tgaaaggagc atctccaatg aaagcagtca cttggcaagg aaaacagaaa
   100441 atggaaatca gaaacgtaga tgatccaaaa atattagaac caacagatgc aatcatccgt
   100501 atcacagcaa cagccatttg cggctccgat ctgcatcttt accatcatgg tgaagcagtt
   100561 ttggaaaaag ggtatgttgt aggacacgaa ccaatgggaa tcgttgaaga agtgggatct
   100621 caagttcaaa cattgaaaaa agggcaacgt gtggttatcc cttttaatat tagttgtggt
   100681 cattgtcatt tctgcctgaa tcacatggaa agccaatgtg atgaatcaaa tccagatcag
   100741 ttatatggcg ggcttttcgg atttggcaag ttgaacggta atcattgggg tggtcaagcg
   100801 gaatatctaa gagttcctta tgcagactct acttcatttg ttgtaccaga taatgatctt
   100861 cctgatgaaa aagttttatt tctatcagat attttgccca cagcttattg gagcgttgaa
   100921 aacgcaggag taaaaaaagg cgatacagtt gtgattctag gttctggtcc agtcggtcta
   100981 ttcgctcaaa aattcgctgt tatggctgga gcagagcgcg taatcgcagt agatccagta
   101041 cagcaccgtc tagataaagc ggctaattac aatggggttg aaacttattt cttagaagac
   101101 acggcacaag ctggaacaga attgtatgaa ctggctaaag gtggcgcaga tgtcattatc
   101161 gattgtgtag gaatggacgg attagagcct gtcaaagaaa aagcgaaaaa tttagtaagc
   101221 ttacaaagcg gcacaatctc tccattacag atggcatcgc aagctgtcaa aaaatttgga
   101281 acagtccaag taactggtgt ttatatgact ccagcttctt cttacccgct gcaagaattt
   101341 tttatgcggg atatcgctgt caagcatgga caggcaccaa ttatccatct aatgccaaaa
   101401 atttacgcaa tgattgcaga aggactattc gatcctacac aaatcattac tcattcgctg
   101461 ccactatcag aagcagcaca agcatatgag atctttgaca aaaaagaaga taaaaatata
   101521 aaagttgttt tgaaaccttg aattcagtaa aaaatacagg tgattttctt tatgcccaaa
   101581 atcaaacgaa atacccatga gatcgaaata ggaaaagaag aagatatcga aatacgagga
   101641 cgtcgcttcc gcttctattt ccaaaatcgt tacacattga tctcactggc tgtcgattta
   101701 ttaaccggga ttttctatat ttttggaagc cttgcttcct taactaaaat ccccgatcga
   101761 tatggcacct atttttattt ggctggtgct attttcttga cgattcgtcc tattctcaga
   101821 atcgtaagga acatttttat ttacgacgaa aaaaaagcaa tgaagagaac aagcaaaaaa
   101881 aaagaggcat gagaattttt caaatctcat gcctcttttt tcaccctatc gtatcacttt
   101941 gatacagacg agcggtcgtc ccactttctt ccttgaccat tgtcaaaaat gtccactcgt
   102001 atcgttcata aaacgtggta tgatctgtaa ttaagtaaag tttttcgtac ccaagttgat
   102061 gcatttcttt tctgatttcc gctaatatcc gcttggctat cccctgctta cgcttttccg
   102121 gttcaacaaa cagggcacaa agatttggtg tcagatcagg gcggttatgg aagtcgtttt
   102181 caatgacgcc cgctcctccg acgatggttt ctttttcatc taagaccaca taccattgag
   102241 gaatactttc cttattagcg attccagtac gaatactttc ctcatacaca acagcaggaa
   102301 ctccccattt tgatgaaaac caattcgcgc tttgttttac taattctggg tgttctctta
   102361 atttgatcca gttatatgta accaatgttt aaacctccga ctaaaataaa acgtttacaa
   102421 aaattataca agtctttatg aaaattagca atgacaacaa tagtgatgta aaaaaaaaaa
   102481 cggaaaacaa tcacttgttc tccgtttttt gattgatcaa gcatctaaag cttcttttct
   102541 tctttcttgg atcgtagcta ccttgacgaa cggtagatag atcaaaatag aaagaaccaa
   102601 attgacagcg gctagtacac cacctgcaat actttttgtt gccaatacac cgccaataat
   102661 tggtggagtt acccatggag gcataacggt agctgctggc actaaacctg tagaagtcgc
   102721 aaagtaagca acactaacta agaccattgg tgtcaaaata aatggaatga acatgatcgg
   102781 gttcaacacg ataggtaacc caaacatcgt tggttcatta atattgaagg acacctggcg
   102841 caatcgacaa gtttgttaca accatatatg gtttgttttt acgtcctact aaataaatag
   102901 ctaacagtaa acctaaagtt gcacctgttc ctcctaagtt gacaaagctg tcaaagaaag
   102961 gtttgttcac gataaacggt gcgctatgcc cagctgcgat tgcattaacg tttgcttcaa
   103021 tggctggcgc attgattgtt tgcatcaaag gatcgaccat attcgctccg tgtaaaccaa
   103081 agaaccataa gaatggtgtg ataaatgcaa gcagtaaggc agatggataa gagtttgcaa
   103141 gtcccataaa tggttcttgg accactgtat agaaagaacc tacgatatca tcaacaccga
   103201 atgcagcaaa aattgcagca actaaagcaa acgcagagat agtgatcatt gctggtagta
   103261 atgaagcaaa tgcttttgca actgccggtg gcacaccatc aggcattttg atgatcaatt
   103321 tttcatttcc gcttaaacgt acaaagattt ctgttgaaat aatcccaaca ataatagcaa
   103381 taaacaaacc gtttgagctc atacctaatg ctccgcctaa agcgaagaaa gagcctaaag
   103441 aaatcacacc tgcggaaaca ccgtcttttc ggtagccgtt agctaaatga taagcaagca
   103501 agaaagcaat caagacagaa agaatggcaa atgtaccgtt ccaagcagca gccccgaatc
   103561 ctttccatga ttcaccacca aaaattgagt tcatcaattc ttggaacccg ggaatcggta
   103621 agttattgat cattactgct aatgctccta agatcattaa cggcatactc accataaatg
   103681 agtcccgaat cgcaactaaa tgccgttgtg caccaatttt tgatgctaca ggtataaaat
   103741 gtttctccat aaatgcaaca aatttatcca taaatcttcc ctcttttctt tactgtagat
   103801 tacgcgttca atcgacgata cagatcaatg atctcttttg ctaaatctgt aaaagctata
   103861 gatgtcatca gatgatcttg actgtggacc gtcaaaagcg tgacttcaac gtgatttcct
   103921 tgtgcttctt gtgtcagcat ctctgtttga gagtgatgtg cttggactaa agattcctct
   103981 gcatctttga ttttttcatc tgctaaagtg aaatcacctt ttttcgcagc agcaatcgct
   104041 tccattgcat cgctttttgc atttccgcca aacatgatca gacccatgat ggcttctaga
   104101 tttttttgat cttccattta ttgtatcctc cgataatttt tattatttgt ttattagttt
   104161 ttctgcttgg tcgagtactt tttcaccatt catcatgcca tagtcagcca tattgattac
   104221 atctaaagga atgcctttag gtgctagctt ttcagcaaat tgattttgca taaagcgtac
   104281 ttgcggtcct aaaagtaaaa cgtctacatt tttagattct agttgattat ccgcatctga
   104341 agcagataca gcaaagatgt ctgcttccat tccttttgct tctgctgcct tttgcatttt
   104401 tgtgactagg agacttgtac tcattccagc tgaacataca agcatgattg ttttcttttc
   104461 cattttaaac acgttccttt ctatacttac acttgtatat aagcaagtag cgtgccaact
   104521 ttaaaagcgc tttaaaaagt tgatatcatc acatttaagg tctataccaa gttgcataca
   104581 cactaaaaaa gaaagcgcac actaaacaca caaattaatt tttattacct tttttctttt
   104641 aacgtgcaca aaaaaagttg tgacacaaaa cttgtcacaa cttttttcaa ataaacggta
   104701 ttcaaaagct tgcatctgcg gtaataagtc caaccaagtt aaaaacataa gatgttgttt
   104761 ttactttgct attcttatta cttgatgcag gacagctttt tcacaacctc tcaataaacg
   104821 gtgttcaatc agctgaccct gggtattagc tcaaaacgct ggattcacaa cctcttttat
   104881 ttcaaataac cagtaaatac aatgaacatc tacaaaaaac ttctatttat ttatagattt
   104941 cgtcaggcaa atccaattct ctcttatcaa tcaaagtctg ataccacgaa gcagattttt
   105001 tcaatgttct gcttcgttca tcgttcaatt cgattcgaac taatccatat cgattcttaa
   105061 atgcattcat tggtgacaca cagtcagtga atgcccataa catatagcct tcgcaatttg
   105121 cgccttcttc tgttgctttg atcaagtaat gcaaatgctg tccgataaat tcgatacggt
   105181 aatcatcttg cacgattcct ttctcatcca tatactgttc ttcatattct cttcccatac
   105241 cgttttctgt tatcagccaa gggatattat gataattttc ttttagatac atggctatat
   105301 catacatgat tttcggatag atttcccatc ccctggaatt attcattttc ttcccaggta
   105361 aatcaaagac ttcataatat cgttcaggat ggaaaggtgt ctcttcattc cattgataac
   105421 gaggggcgcg aacgcgttta ggataatatt gattgattcc aaggaaatct actgtatgat
   105481 gctgaatcgt ttctaaatcc tctgttgcag gatcgaaata aatcgattgt ttttgacaca
   105541 actccaggaa ctcttctgtg tagtatcctt ttaccatcgg atcaaaaaat actcgattat
   105601 aaaacaaatc atacatataa gcagcttttt ggtcttctgg agaattggat cgagcataga
   105661 ccatttcagg atttaaaata cagccaatcc ttccaccata atttccgctg cggtaaatct
   105721 ctactgcttt agccgttgct aaaactttat gataattcca catcatccac ttttttgtgt
   105781 tttgttcatg cggccagcga acagcatcca aatagcaacg cgtttgggga acgattggtt
   105841 cgttgaatgt aaaccagttt tttaccctat caccgtaacg atcaaaggca atttgagcat
   105901 acttagcata aaaatcaact acttttcttg aagaccagcc atcatatttt tccaaaagaa
   105961 aagctgggac ttcataatgt tccaaacaaa tcatcggttc tacgtctgct tcgatcaaag
   106021 agtcgatcat ttcacttata tgctgagcat attcttcatc tactatacag ttctcataat
   106081 cagtaaaaaa acgagcccaa ttgatagaag tccgataatg tgtcagatgg atggatttca
   106141 tcagatccac atcctgctgg tattgttcca taaaattagt tgctacggct gggccatacc
   106201 cattatgcca aacaaaatgt tcatttttat accagctatc tataaacgaa tcctgtcctt
   106261 ctttttttcc tttccaacct tccgtttgcc aagcagaaga tgcagcacca agaataaaat
   106321 tttttggaat agtaattttc atgatttcct cctgtttttt agatcccatc attttccaca
   106381 cgatttgcta cttttacaaa tggcagatag atcaaaatag aaacaataat acaaacaagt
   106441 tgcgtaataa ctgcaccgat atttcctgct gttgccagat aagcattgac gatcggcggc
   106501 attggccaag ggaccattac aactgctttc gccgcaaatc ctaaagcggt tgcaaaataa
   106561 ccaatcgttc cagtgataag aggcgttaag ataaacggaa tagctaaaat tggattcagc
   106621 atgatcggca taccaaaaat aactggttca ttgatgttga agatcccagg agcaagggat
   106681 aacttggtga tttgtttcat atcttcccgt tttccaacta acaatactgc aatcagtaaa
   106741 ccgatcgtga ctccagaccc gcccatactc atatacatat cccaaaatgg catagtaata
   106801 atgttcggta cttcttttcc agcttcaaaa gcttccgtat ttacagcaat tgccgctaaa
   106861 agcaacggtt cccgtatcgg cttcaccatt tgatttccat ggataccaat cacccaaaag
   106921 acttgcgcaa taaacatcaa tagcaaaata cccggtaacc cttgtacgac accttctaat
   106981 gggcgttgta cgacattgta aatgatatca taaaggtaca ttcctgtaag ttctttgatg
   107041 ataaatcccg cagccgcgat acccgataca gtcagaatcg tcgggaataa agcagaaaaa
   107101 ctagcagaaa cattcgttgg cacggtatca ggcattctca gctgtagttt cttctgtttc
   107161 ctcaaccagc aataaagttc aatagaaagg atggagacca acattcccaa aaataaccct
   107221 ttcgtatctg tatattgttt agccaatacg ttttctacta taacagtctg attttcattc
   107281 actaattcat aaacagttgg attaacagat aaataagaca tcactgcgat gataccaggg
   107341 aatacaccat ccactttatt cagcttggct aattcgatcc ctatcagaaa aacagcatag
   107401 atggtcaaga aacttagtgt gacatagctg atggcagatg cgataggctt taattcttct
   107461 aaaaaacgca agaaacttat ctgtgctaag ccattttccg agtcaaagac cattgctgaa
   107521 aacaatgtgc caaaagcacc cgtaataatt accggaatca atgcagcaaa tgcgtttttt
   107581 atcaccatga tataccttaa attattgatt ctcgttgcca cgttccctaa aacattggct
   107641 aatttatcca taaaactcat tccagatccc ctcattcctg cttcttctcc ttgacgtcat
   107701 ctctttttgt ctattagtca gcgcttacat ttcgatgaac agaaactatt tactcctctt
   107761 ttttaccaaa tataaaacaa aaattcatct gatgtattta tcataaaata catcagatga
   107821 actgtcaatt agtttctttt tctcctatta ttttctgtaa ttctctccga tttattgcca
   107881 tatggacagt cattgcatca aacgcagcaa gtgcattccg cctttcgatg gcctgaacga
   107941 tctctgtatg aatatcgatc gtctcgattt tcagatgctg gatatcataa tttttattaa
   108001 acaaagcaat tgattcatta atgattggga taatatgcag caaggctacg tttccgctag
   108061 cttctgcaat catcgtatga aaatcgatgt ctaattgaac atgttcttgt gtgccttctc
   108121 gaaaagaagt ttcaatcttt tgcgttaatt ttttcatttg gacgatttga ttcttcgttg
   108181 catattccgc tgccaaacct gccatcttag gctccaataa atatctcagt tcaaataagt
   108241 ctcgtatcat ccgatcctga tcttcaatca aagaaaaacc gagtgggtca ttggcaatcc
   108301 ctcgcttatc actgacaaat gtccccgctc cttgccgaac ttcaaggata ttcctggaag
   108361 ctagagcccg cacagcttct cgcaccgtgc ttcgccccac ctctaaataa tcggacaatt
   108421 catattcatt cggcagttta tctcctactt gcaactgcat ttcctttaaa tatctaagga
   108481 tcttgtcagt agttacttct actagggttt tattttcttc caaaccacat acctcctttt
   108541 catctgatgt attttttcgt aattattata acacgtttga atcatctgat gattttttgt
   108601 atacaaaatt gattaatccg ttcatagaca tacaaacgaa gaagatattt accataaaaa
   108661 agactaggat aaaattcact cctagccttc gatcattttt attttgaacg acaaaaaata
   108721 tgatgttcaa taacagacga tcttcattcg attcttgatg tcatcttttg ttttttttaa
   108781 tatatggata aaaagtttga ttacatcgtt tctattctag aatttggtcg attctcaatt
   108841 cttcttctgg tgagaaatct aaattatcca tcattcgaac actttcttgt aactgactta
   108901 accgacttgc tccgaccagt acacttgtaa cagatttttg tcgcaaattc catgcaaggg
   108961 ccatttgcgc taatgattgt cctcgtgata cggcgattgt ttgcagtgct ttgatttttt
   109021 ccagagttga tccaacttgt tcttctgaaa ggaatggtat ttccttacga tgtgctctag
   109081 aatcttcagg aataccatgt agataacgat ttgtcagcaa cccttgagca agcggactga
   109141 acgtgattgc ccctagccct tcttcttcta atactggaga tagatcgtct tctagtagtg
   109201 cacgagaaaa catattgtag cgcatctgat gaataatgaa cggtgcttcc tttcttttta
   109261 aaatttcagt catttttttt gtatcttctc cattatagtt ggatatacca atatataatg
   109321 cttttccttg tcttacaagt tgcatcaaag cttctgctgt ttcttccaaa ggtgtatcag
   109381 ggtctgggcg atgatgatag aagatgtcaa cataatctag ccccattctt tggagacttt
   109441 ggtcacaact tgaaatgatg gatttacgag agccccattc cccatatggc ccttcccaca
   109501 tatgataacc tgctttgcta gaaataatca gttcatcacg gtaggcttga aaatcttctc
   109561 taaaaatacg cccaaagttt ttctctgcag ctccagcagg gcctccataa ttattcgcaa
   109621 ggtcgaaatg ggtaattccc atgtcgaatg cgcctcttaa aatctctctt tgattatgga
   109681 taggatcata atcaccaaaa ttttgccata atccgagaga taaaatcggt aatttcaaac
   109741 ctgaatgacc ggatttacga tattccattt tttcataacg tgcactatct gcaatataca
   109801 atttttctcc tcctcatcaa atctttttaa aacgctttct tttttctatt tttagtttac
   109861 tacattttaa agaaaaggag ttaatcaaaa tgattttttc gtatattttt ttgccatttg
   109921 ttttttactc gttgatagat cagaaattga ttacgtgctt gctggatttt tttataacgt
   109981 ttcggttgtt ttttgtaaaa ttgctgatga tagttttctg ctggccaaaa cgtaccggct
   110041 ggttcgattt ttgtgacgat tggttggtgg aaagttcctg aactgtctag tttctgtttt
   110101 gattgttccg ctaattcttt ttgtcgttcg ccttgataaa aaatcactgg acgatattgc
   110161 ttccctctat cttgaaattg tccaaatgta tctgtgggat cagtaatttg ccaatagatt
   110221 gtcagcaact cgctataact tatttctctt gtgtcataaa tgatctccac agcttccaca
   110281 tgacctgtgt aaccaccact tacttgatca taatttggtt tttcaacatg tccgcccgtg
   110341 tatcctgaca aaacagatag gatccctttt ttcgattcaa acggctcgac catacaccag
   110401 aaacatcccc ctgcaaatac tgcacgttct tgatagtcag catcttgcat ggcatgcttg
   110461 gaaaagtcat atttttgctc cttatcaaat ccttccgtaa tcaataaata aaagtccatt
   110521 acatcaggcg tcagattcat tcggatagct aatggacgta gtgttgcttc tagttttgat
   110581 aactgttctt taacggatat attttctctt atgtcattct ttgtctgaat caatactttt
   110641 cgttcccaat ctcgtgtatt cggattcaaa atcagattat aaagtgtttg aatgaatatt
   110701 tgttcctcat ccatagattc tcctcctttc cgaagaagac aagctagtga ctttagctgt
   110761 aatttatcat aaagtgagga aataagcgat tacttcatcc ccctacagat ttttcgtata
   110821 aaaaagagag aatccttatc gacagattct cctttttaat caatttattt tataaatgaa
   110881 aagttaattt accttttatg gaaaactatt ttaaaaaata aacataaata tgcagttaat
   110941 gtaacaagat aagaaataat agtcgttact gtataacttg tgcttacttt aatatcagca
   111001 actcctttga ctccgcttat ttgtaccaat ccattagcat tcacctgctc ctttacaggt
   111061 tgatgattta tttctacatt cgttcctaaa taagcatata caggaagtgt gattacttgg
   111121 ctcttctcat tagttactct atatatgata gaactaccag ttgttttata aggaaggttt
   111181 acccattgac tgccaatctt tgcttcgtgt tttattatat gctccttatt ctccaatgaa
   111241 gcgataggag aataatcata taaaaaataa tccattcctt tagtggtata cgcctctact
   111301 gtttctttgt ttacaacaat atgtcccggc tgagaaatta ttttttgatt gaaatttttt
   111361 ttactagaaa cagttaaagt gattaataac aaaacagtca taaataaata aaatagttct
   111421 cttgtcttat tgtatcttct atttttgaaa aatatcatcg ttaatatcag agaagagaat
   111481 attatttgca agcttaagat ccgccaagga aattgtaaca atttggctgg cgtattttgc
   111541 agaagatacc atggcaccaa actagttgta gctagccaag tcaaacacgt accataataa
   111601 atcttttttt ctatgtttgt taatttttta aataaaatca ggggaataca taaagataac
   111661 agaccaacta gtcccattga gtaagtagtt aagtcgttgt tcatagcttc agtcagacta
   111721 tcgaacacat tagatgcatg agcatataaa tttgtcacgc taggtttgtt gattttttgg
   111781 tagagcattt gttcaaacat cggataccaa aaagcactcg tcagaaccaa tgtcattcct
   111841 gccgcactaa ataatttttt aaatatagca ataaaatctg cattcttgaa acctttagaa
   111901 accaaacgaa taaaaatgat aattaatgct gtactcatta atgttgatag tacatggctg
   111961 tacactagca aactcatact caatgctagc tttacagacg gatacttttc ttcttttcca
   112021 gagatgattt gataagcata aaataataca gggataacaa gtgttattgc gatagcttcg
   112081 gcaattgcgg aacgatagta gatgtctact gtccgataag cagagaaaat atagagacaa
   112141 ctaaataaaa atgccgcttt tttttgtttt aaaaaccgct cgccataatg ataagctacg
   112201 agtgttgtac acaagttcaa taaccaaacg taaataatat agcttacaat caaatttttt
   112261 gtcatccaat ataacattac agctggaaaa aaagtcagaa agggataaaa ataatttaca
   112321 ccatatccag tataattgaa tgtctcataa ttaatcggac tggtaaaaat agtcgataac
   112381 cccttgattc gagataagtg aaaagaaaga tctccagtgg tataaatact ctgtgtattt
   112441 ttgaaaaaga tgaaagaata tatactacta actataatta atccactcaa tattactact
   112501 tttttattta ttttcattct tcttgtttat ctccttttta gtcacatatc gagaatcttt
   112561 caacttatta ggtgcaaatc gtttaaaact tgaatacacc actaaacaat aagtcagaat
   112621 actgatccat aaagccatga gagcagttgg agtatatttt gttgtaattt ctatcttatt
   112681 ttctccagca tttacatcca cattcactaa gccatgtttt ttataagagt catttacgac
   112741 tttaccgttt acttttacct gtgtacctaa ataagcatat actggtactg tcactttttg
   112801 ctttttgttg cttgccactg tgtaagtaat gttattatct gcagctttat acttcccttt
   112861 ttcccacgat tctcctactt ttacttcatg tttttctaag tgaggccttt cttttatcgc
   112921 ttctgttggg gcgtaatcgt ataatcctcc catatctgat gttgtataac gtgggagtgt
   112981 ttcttcattg ataacaatat gaccgtgttt tgattggata acttttgcgt aattttcttt
   113041 tgctgctata gacgtgacga gtagaaacac cacagtagcg ccaatgatta accatgaata
   113101 ttttttattc atagtctttt tcataaaaac aagcgttatg atcattgaag aaaaaaagat
   113161 ttggatacct aagatacgcc aaggaaactg gagcaagctt atcggtgttt tttgaaacaa
   113221 aaaccatgga aataaattag ttacgcatac ccatgtagaa actacgccaa catagatgat
   113281 tttttctttt ttctccattt ctttcagtat gaataaagga aaaatcaacg caaccaatcc
   113341 taataacccc atagtgtatg ttgtaatatc gttatttaac gcttgaatga tactatctga
   113401 aatagaaagt gcttctagct gcaaatctgt tttgaaggga ctgtgtattt cttgataatt
   113461 catctgctgc aacataggat accaaaaata gctagttaat gcacaagtca aaaaaacagc
   113521 ctttactaaa ttcacgacca caaattttat atcgtttttt atttgcttgc ttaaaaacaa
   113581 acgaactata atcatacaag caatcaatgc actacacaat agtgtagtta agacatgagt
   113641 atacacaagt agacttatac tgacagataa agcgatgact tttttttctc tattgaatat
   113701 caatccataa gcataatata aaacagctgg gataatcgta agagcgattg cttctgcaat
   113761 tgcggatcga taatagatat caactgttcg ataagttgca aaagtatata aacaactaaa
   113821 taaaaaagca gcatctatct ttttaaaaaa cttttctcca taataaaaac
//
LOCUS       DAFBVQ010000002       106749 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.002, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000002 DAFBVQ010000000
VERSION     DAFBVQ010000002.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 106749)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 106749)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..106749
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.002"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(715..3864)
                     /locus_tag="LLC22_000100"
     CDS             complement(715..3864)
                     /locus_tag="LLC22_000100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction endonuclease subunit R"
                     /protein_id="HBK5433410.1"
                     /translation="MKISHREEAEVEEQLIRVLGEGHNQWTYRPDLKSEEDLWVNLRQ
                     KIISNNQAELNDFPLTDKEFETIKTELLLRTKTPFDAAKWLKGENGMARITIEREDPQ
                     LGSVSLILYSNQDIGGGISTYEVVHQIAKRGSNIEARDRRFDVTLLINGLPIVQIELK
                     QVTAKDSFYQAFNQIKKYAEEGMFRNNIFSTLQLFVVSNEQTTRYFANALPKDLHPKF
                     LFSWRTKDNKKVENLYEFCKQVLNIPDAHRLIADYTIVSEDQDNKILMVLHPYQVHAI
                     QALFIAANKHQSGYVWHATGSGKTLTSFVSTKLLARKSGIDRTIMLVDRKDLDNQTTT
                     EFTKFASEFNTGISSGNAKANSLIVGTGSAKELSETLLADANANVVIITTRQKLDAAL
                     KYAKKQEEKKGTNRFQKLMGQHIVFVVDECHRALSAENMEEIKKMFPKSTWFGFTGTP
                     IFPENRKQAKGQLARTTHDQYGEVLHTYTIKNALEDGSVLGFQVEHENTVEPTSLENK
                     IYRKLKEVETYAEYSPEQINRMIDQMEPVKKESYLDPTVFEADEHIQKVIHKMFRPDN
                     AYTKFDFRNGRPTKSAILTTSSIDMAKKYYRAIKEMTKEPDWLTKEFPNQPIREGRTM
                     EDPDFPRIAITYSLEENSRDSSVQQEEMQKIIEEYNQYYNTSWSLADIERYNGDINNR
                     LARKRAEFKQFGKQIDLVIVVDRLLTGFDAPTIQTLFVDRNLEYAGLIQAFSRTNRTY
                     PEKTKGLIVTFRKPATMEKNVEDATKLYSEAKEESGLIYPSYQESKKRFKQAYGKLKE
                     VSSMESIDEHTPLEIRIEYVKAFQELNRAYESLVTYDDYNDDMVKSSTLNNQIQLLEE
                     QIGVYETVKGSLIEEEPEKEGEDFSTIEFYSENTTKLYDIDSTYIDQLLGTYAANSSD
                     AREEIEKALAKLNKTEGVKEVYRQILNAFDVGTLDSNEDIFVIKRRYFTQASDDLIHV
                     FSNEWFVSEKELHASNLQYMPGEDPIPNMKAIINSKDYEGYKANHPEAKPFKYPQEMK
                     RAWRKMLDDELIPLENELR"
     gene            complement(3878..5122)
                     /locus_tag="LLC22_000101"
     CDS             complement(3878..5122)
                     /locus_tag="LLC22_000101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="restriction endonuclease subunit S"
                     /protein_id="HBK5433411.1"
                     /translation="MSNDIQPEIRFPGFTEAWEQRKFECLLDKKDGVRRGPFGSALKK
                     EFFVSNSNFVVYEQQNAIYDNYETRYKITEKKYNELIKFKLEPGDFIMSGAGTIGRIS
                     RVPKQIKPGVFNQALIRLRINKEITDSEYFIQFIRADFMQRKLTGANPGSAITNLVPM
                     SEVKKWIVQFPILEEQKKIGNFFKQLDDTIALQQRKLDLLKETKKGFLQKMFPKNGAK
                     VPEIRFPGFTEDWEQRKFKEFSKKTGKKNTKDLDFPAYSVSNKAGLISQTEQFDGSRL
                     DDLEKTNYKFVEPNEFAYNPARVNVGSIAFNNLGMTVIVSSLYVVVKMSEDLDNEFIL
                     QFIKSPTFIKEVKRNTEGSVREYLFYENFANIKFPFTRNKEEQQKIGAFFKQLDDTIA
                     LHQRKLDLLKETKKGFLQKMFV"
     gene            complement(5115..6707)
                     /locus_tag="LLC22_000102"
     CDS             complement(5115..6707)
                     /locus_tag="LLC22_000102"
                     /EC_number="2.1.1.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I restriction-modification system subunit
                     M"
                     /protein_id="HBK5433412.1"
                     /translation="MGAELNQKLFSAADNLRSKMDASEYKNYLLGLIFYKYLSDRLLE
                     QVVLLADESLEEYDTVSKQTMLYRELLSDEESKEDLIATIVDILGYAISPEYLFNVLA
                     DQAKQATFQLNDLNKAFVQLASTYNQFNGLFDDVDLQSKKLGTDEQQRNVTITEVIKK
                     LNDVEVLGHDGDVIGDAYEFLISQFASEAGKKAGEFYTPHMVSDMMAQIVTLDQKERR
                     FFSVFDPTMGSGSLMLNVRNYLTHPDNVKYHGQELNTTTYNLAKMNLILHGVDAEEMN
                     LRNGDTLNKDWPTDEPYTFDAVVMNPPYSANWSADTTFLDDSRFNRYGKLAPKSKADF
                     AFLLHGFYHLKETGTMAIVLPHGVLFRGAAEGVIRQKLLEDGSIYAVIGMPANLFFGT
                     SIPTTVIVLKKNRQTRDVLFIDASREFVKGKNQNKLSEENIQKILETYAERKDVEKYA
                     HLANFDEIKENDYNLNIPRYVDTFEEEEPIDMVHVGNDIKKIRQEQQVLEKELLEAIS
                     SLQTTPENEAWLQGALEVFKHE"
     gene            complement(7216..7941)
                     /locus_tag="LLC22_000103"
     CDS             complement(7216..7941)
                     /locus_tag="LLC22_000103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433413.1"
                     /translation="MKKKKLLWICLAILLIIGGIEIFTTYRLKTNQPKQYVSDMLNII
                     EEIDSEMKAFSKTSMDLGERYDFKGFMEDKMDEVSSREIPEGTPKAVRDTKDTLLEAI
                     DNVNTALLTNDVKLLEQGQLCFSIAQAIYTEFLDGNIKEKSLNEKLNSFVETYTAIPP
                     TWKLVNEDKGITINTDTEISTDAQSLSDLLANLTGISNAVTEKVGKDIPLRLLENGKK
                     DYSVVFKNGQVTDYNEVFKKVIE"
     gene            complement(8095..8421)
                     /locus_tag="LLC22_000104"
     CDS             complement(8095..8421)
                     /locus_tag="LLC22_000104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433414.1"
                     /translation="MNKVNMNKKFVIIGIVVLAIIGIIFSRMTGSSGLEKSSVPLVTQ
                     ILQEQYNLNRTCDDVTITHDNGDNTYRAKATLDNGSAININVEYYPKKDRVYVEIPYT
                     EVLMLN"
     gene            complement(8458..8823)
                     /locus_tag="LLC22_000105"
     CDS             complement(8458..8823)
                     /locus_tag="LLC22_000105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ribbon domain-containing protein"
                     /protein_id="HBK5433415.1"
                     /translation="MYCRKCGKEITNESKYCQFCGALQETDETTGTDTVKKSTEQTIN
                     EMKEQIVHGQETGKLYLIIGWISMVVSLAFIPVVFGAVAVIMGYLYREKDEQMGTILM
                     IAGVAGAIFGVLLGMSMSY"
     gene            complement(8860..9075)
                     /locus_tag="LLC22_000106"
     CDS             complement(8860..9075)
                     /locus_tag="LLC22_000106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5433416.1"
                     /translation="MKKVSNLSRYRKEKGLSQTELAKKMNVTQQCVSSWQTGRTIPKP
                     YQMKMLSEILSVPINELFSDVFNKVNS"
     gene            9204..9539
                     /locus_tag="LLC22_000107"
     CDS             9204..9539
                     /locus_tag="LLC22_000107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5433417.1"
                     /translation="MKQKQYAKVIREKRKALGWTQKELAKKIFSTQQAVARWENSVTE
                     PNLDSLTALSRALGTPVSHFLDNVDIDYEEEFLALYRSLSTEDAIRTIDYMKLLKRQE
                     NERNQLLKD"
     gene            complement(9615..11612)
                     /locus_tag="LLC22_000108"
     CDS             complement(9615..11612)
                     /locus_tag="LLC22_000108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331149.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433418.1"
                     /translation="METSMINIPIYVDQEKLLEKPVTKKEKTDVRDRCLDNYREVTRD
                     EFVEILNSSQSFIPSKTKNKGNDKESFVETRVIILDVDNTVKDEKGKVVDLSKDDSRY
                     LSIEKVLSINLVHNSAFAIQKSIRYSENLEKYKIVFLLKEAITDYGKMVAVYEYLKKN
                     IPGCDDNVNASNRMFFGGYKSDAVIIINEDNMLDITELPIDFTMTCSKNCQSDSGREY
                     ELVNETDFVKLIKNDDKEEMKQWFKDCLFDSSDMSFNEIYERLLTIDMNKLLKSSKNL
                     RCLFHNDHNPSASIFTSKTGHSIFYCHSSNCDISENFIGVVMLILKKDSRVETFNWLL
                     ENLDLYPTHFRKLKEESKVLFDTLESMKDKLFRTIRNYLEEMRRVYDVLLSDVNFFDD
                     SKESVTCILSGEQLAKKMSSYYGKTYDIDKCNKLLSLMTFIGLIKKLDDEDVPLKMLE
                     YLNRLKEEKALGNFKHKRSNVYRLDVFNATSVIQKLNEDILPLLEKFHFTYQYFSYEW
                     VKICFNEKEAKRVFPQNSRSELSKEKQLILDEAHEVLQGLSWQGTYLMTEKELINTVC
                     ERLRNVRDNSVKNALIENRGYFVKQGFTLERASKDIKKLYNVKASSSFLVYLAKGAGI
                     DEVIKELILSGVELVPIYQFTSVTRDDGRRVRNRRDPIILN"
     gene            complement(11710..11985)
                     /locus_tag="LLC22_000109"
     CDS             complement(11710..11985)
                     /locus_tag="LLC22_000109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433419.1"
                     /translation="MSLQIIDSIVSIQVEQQVKEIITVLKPMLEDIISGVTLEYMDYQ
                     QASEYLGVSVGTIRKYVSQYGLPVIKIDTVIRFKKSDIDSFMERYKG"
     gene            12217..12951
                     /locus_tag="LLC22_000110"
     CDS             12217..12951
                     /locus_tag="LLC22_000110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5433420.1"
                     /translation="MIKRPPINYLERKKILGTKIKAIRKSKKLTQPAFGLMINNGQLI
                     DKKTIYEWEKGTYLPIPERLSRIADLGNMSIEELVCGNVEEYILGIILYRDSIVLDGI
                     TFPDKNLFQHLRQQFPPVHSNLDTWLDRYSKLEPEMQEFIANKTCNKVKNEKISLFNI
                     LKIEELFINAIVEEFDNNILFLTSSIEELLERMVDEWLPIQLKDMSYPEEAVREITDN
                     INKLEQTISSIGKKYTKKKMKGGDTI"
     gene            12990..14132
                     /locus_tag="LLC22_000111"
     CDS             12990..14132
                     /locus_tag="LLC22_000111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5433421.1"
                     /translation="MAKISKYKKKNGQVAWMYKGHIATDPRTGEKINTTRRGFSSKQE
                     AQKDYDEYRHQILYGVKKKAPDMTFEDLYNEWITHQRTSVKASTIAISVRYANNQILP
                     AFGKLKLSNISVPYCQKVVDEWHSKYESYDYMRKQTAQILRYGVAMQYIDNNPMEKTL
                     LPRKKEYEKNRKFYSKEELNNLLDAFKDFGNMKQYAFFRLLAYTGMRKSEVLALQWKD
                     IDTFNKELHVNKTLAVDEFGKVIIQSPKTRASRRVISLDTETLSILNNWKLQQKEEYL
                     KLGYNTSSKEQHVFTTVKNTLYIPNTVNDWLRYILKKYNLPRITPHGFRHTHASLLLE
                     AGESVKVVQQRLGHENSKVTLDIYAHITNNAPKKTGQDFADMMAHQ"
     gene            complement(14227..15618)
                     /gene="sufB"
                     /locus_tag="LLC22_000112"
     CDS             complement(14227..15618)
                     /gene="sufB"
                     /locus_tag="LLC22_000112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufB"
                     /protein_id="HBK5433422.1"
                     /translation="MGVPELEEYKFGFHDDVEPVFSTGEGLTEEVIREMSRIKGEPEW
                     MLEFRLKSLETFNKMPMQTWGPDLSDIDFDAIKYYQKPSDKPARDWEDVPEKIKDTFE
                     KIGIPEAERAYLAGASAQYESEVVYHNMKDEFEKLGIVFTDTDSALKEYPELFKEYFS
                     KLVPPTDNKLAALNSAVWSGGTFIYVPKGVKVDVPLQTYFRINAENTGQFERTLIIVD
                     EGASIHYVEGCTAPTYSSNSLHAAIVEIFTRKDAYCRYTTIQNWSDNVYNLVTKRAKA
                     YEGATVEWIDGNLGAKTTMKYPSVYLDGKGARGTMLSIAFAGANQIQDTGAKMIHNAP
                     NTSSSIVSKSISKDGGEVNYRGQVTFAKNSAGSISHIECDTIIMDEWSKSDTIPFNEI
                     HNSQVSLEHEAKVSKISEEQLYYLMSRGLTESEATEMIVMGFVEPFTKELPMEYAVEL
                     NRLISYEMEGSVG"
     gene            complement(15623..16093)
                     /locus_tag="LLC22_000113"
     CDS             complement(15623..16093)
                     /locus_tag="LLC22_000113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632039.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SUF system NifU family Fe-S cluster assembly
                     protein"
                     /protein_id="HBK5433423.1"
                     /translation="MGLSKLDNLYRQVILDHSSHPHHRGSLTDSTSKIELNNPTCGDV
                     IELQVDVKDGIIKNIAFDGSGCSISTASASMMTDAVIGKSIEEAEHLTVDFLQLVQGK
                     EVKDPDQLGDAAMLGGVAKFPARIKCATLAWKALGKAMENDGTAAFHHYHKEEE"
     gene            complement(16080..17315)
                     /locus_tag="LLC22_000114"
     CDS             complement(16080..17315)
                     /locus_tag="LLC22_000114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK5433424.1"
                     /translation="MIDAKKLRNDFPILFQDVNDEPLVYLDNAATTQKPKQVLQALAY
                     YYEHDNANVHRGVHTLAERATHDYEQAREKVRAFIHAKETAEVLFTRGTTTSLNWVAR
                     TFGDRYIKAGDEIVLSYMEHHSNVIPWQQLAKRTGAVLKYIELTEEGFLDMEDAAKKI
                     TDKTKIVSIAHVSNVLGVFNPVQELAELVHENGGVIVVDGAQSAPHMAIDVQALDCDF
                     FAFSGHKMCGPTGIGVLYGKRKWLEEMEPVEFGGEMIDFVELYDSTWKELPWKFEAGT
                     PNIAGAIALGHAIDYLQKLGMDNIHRYEEELAAYVLPKLQAIDGLTVYGPQDPNFRTG
                     VVAFNLDGLHPHDVATALDMEGVAVRAGHHCAQPLLKYLEVSATARASFYFYNTTQDA
                     DRLVEAIMATKEFFQHGTI"
     gene            complement(17312..18598)
                     /gene="sufD"
                     /locus_tag="LLC22_000115"
     CDS             complement(17312..18598)
                     /gene="sufD"
                     /locus_tag="LLC22_000115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly protein SufD"
                     /protein_id="HBK5433425.1"
                     /translation="MKEKNWLDYLDAVNDFSLSKGEPDWMRTFRQDALAKADELPLPH
                     IDRVKFHRWSLFDVKETQTISETGTIPAFDAMKDNPVLVQQGSWTIFEQLPVELAEKG
                     VIFTDLFTAMIEYPELVQEYYMKKAVNMNEDQLTALHVAFMNSGIFLYVPKNVVIDEP
                     LESLFIQDGASDEHFFKHVLIVADEHSEFSYLERFQTTKEQVAKSSGNIIVEVIAKAG
                     SKIKYSAVDQLGENITSYMNRRGHILRDASVDWAIGVMNDGHVIADFDSDLAGEGAHA
                     EVKIVAISSGRQIQGIDTRVTNKAPHTIGHILQHGVIREKGTLTFNGIGHILKGAKGA
                     DAQQESRVLMLSDKARGDANPILLIDENEVTAGHAASVGRVDPEEMYYLMSRGLHKEE
                     AERLVIRGFLGSVLTAIPVEQVRKELVEVIEGKLNG"
     gene            complement(18611..19384)
                     /gene="sufC"
                     /locus_tag="LLC22_000116"
     CDS             complement(18611..19384)
                     /gene="sufC"
                     /locus_tag="LLC22_000116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Fe-S cluster assembly ATPase SufC"
                     /protein_id="HBK5433426.1"
                     /translation="MSVLEIKNLHVSIEEKEILKGVNLTMKTGEIHAIMGPNGTGKST
                     LSAAIMGNPNYEVTEGEILFDGKNVLDLEVDERARLGLFLAMQYPSEIPGITNAEFMR
                     AAINAKRDENDKISVMAFLKKLDEKMALLNMPEEMAERYLNEGFSGGEKKRNEILQLL
                     MLEPTFAILDEIDSGLDIDALKVVAKGVNEMRGDNFGALIITHYQRLLNYITPDVVHI
                     MMEGRVVMTGNADLAKRLEAEGYAGISKELGIDYKEEEA"
     gene            complement(19581..20429)
                     /locus_tag="LLC22_000117"
     CDS             complement(19581..20429)
                     /locus_tag="LLC22_000117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK5433427.1"
                     /translation="MKKKIFGFAAALLLTVGLAACGNNSDSKDSANKADDTTLKVGAS
                     PTPHAEILEHVKPLLKDEGIDLEIVKFDDYVLPNQSLEEGDIDANYFQHIPYLNKEIK
                     EKGYDFVNAGAVHIEPMGLYSKKVKDVSELKDGATIITSNSESDWGRIITILQDAGLV
                     KVKDGVDLETATFDDIEENPKNLKFNHTIDPSLLASTYQNDEGDLVAINANFAYGAGL
                     NPLEDAVLLEKDNSPYVNIIATRKGDEDSDKIKKLIEVLHRKEVQEWITDKWGGSVKP
                     VKADAK"
     gene            complement(20453..21139)
                     /locus_tag="LLC22_000118"
     CDS             complement(20453..21139)
                     /locus_tag="LLC22_000118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5433428.1"
                     /translation="MDKSFSETYLDFKQINPETMNQAILDTLYMTLISMVLVTIIGLV
                     LGLILYSIGRKNKPYARIIYGIVSIISNIFRSTPFMILMVLIIPFTKAIVGTMLGAQA
                     AIPALVLSAAPFYARLVEIAFREVSPGVLEAADAMGASYWEIIWKVLIPESIPALISG
                     LTVTTISMIGFTAMAGAIGAGGLGGLAWQEGYQRGNLTVTFVATLIILLIVFIVQGIG
                     DFLTKKTDKR"
     gene            complement(21132..22166)
                     /locus_tag="LLC22_000119"
     CDS             complement(21132..22166)
                     /locus_tag="LLC22_000119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5433429.1"
                     /translation="MSLIQLTNVKKTFNGKNGNIQAVNDVSLNVEKGDIYGIVGYSGA
                     GKSTLVRLLNGLELPTSGEVIVNDQDITKLKNKELRTFRKKIGMIFQHFNLLWSRTVL
                     ENIQLPLELAGVPKSKRKERAEELLRLVGLEGRGQAYPSQLSGGQKQRVGIARALAND
                     PEILLCDEATSALDPQTTEEVLDLLLAINKKLNLTIVLITHEMNVIRKICNKVAVMEL
                     GKVVEEGDVLTVFRQPKKEVTKRFVQQDIEPEADSTELLAELIKENPSGRLATLTFSE
                     RNANEPVISQAIRRYNIDVNVVYGKIKQVKEGSFGSLTVLMTGETKELDQAEVFIKEQ
                     GVGIEVIHRG"
     misc_binding    complement(22229..22485)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(22561..22899)
                     /locus_tag="LLC22_000120"
     CDS             complement(22561..22899)
                     /locus_tag="LLC22_000120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine cleavage system protein H"
                     /protein_id="HBK5433430.1"
                     /translation="MAGKHLKKKDNLWILFNGKEYCVGLTNEAQEELGDITFANLPKA
                     GQSLKKDEPLIEVEAEKAVNEFASPLTGTVSSVNDKIGEDINILNDSDEMNAWILSFK
                     DVDPKEFDEL"
     gene            complement(22901..23257)
                     /locus_tag="LLC22_000121"
     CDS             complement(22901..23257)
                     /locus_tag="LLC22_000121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase family protein"
                     /protein_id="HBK5433431.1"
                     /translation="MYTFYWYPKCSTCKKAKAWLDQHGVSYQTVDMIKEVPKASTIET
                     WLETSQVPIRRLFNTSGMKYRELGLKDQVGEFTASKASQVLSTDGMLIKRPLILREDQ
                     LVAIGFNEKIYEGELI"
     gene            complement(23263..24450)
                     /locus_tag="LLC22_000122"
     CDS             complement(23263..24450)
                     /locus_tag="LLC22_000122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBK5433432.1"
                     /translation="MEKKLKASNDNRIDYGVILPVFLLCLIGLLSLYVALSHDPNNPA
                     VLKGVGMQVVWYLVGAAAIVVIMHLNSKWIWKLTPYLYGLGLVVMGLLLKFYDQNLAA
                     STGSKNWFRFGAFTFQPAELMKIAYILMMALIVTKHNTQVKERTMKSDFWLIGKLLIV
                     TIPVLALIMAQDDFGTMLVFLAIFGGIFLMSGISWRIIAPVVILAVVVGAGTIFLVTT
                     EGGRDLLYKVGFKSYQFARIDSWLDPFHDTSGMSYQPAQGLLAIGTGGLFGKGFNVSN
                     IYVPVRESDMIFTVIGENFGFIGGAFVIFLYFILIYRMIRVCFDTNNEFYAYIASGLI
                     MMLLFHVFENIGANIGLLPLTGIPLPFISQGGSSILGNMIGIGLILSMRYQNEAPARS
                     SRR"
     gene            complement(24641..25486)
                     /locus_tag="LLC22_000123"
     CDS             complement(24641..25486)
                     /locus_tag="LLC22_000123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5433433.1"
                     /translation="MFKLLTTFRAVYETRNFSRAAEVLFLSQPAVSNQIKQLERELNI
                     DLFQRNGRKEMLPTKQADLLYERTLVLLEEWEETQQKLLNEQNEEEVCRIVASHTFAV
                     YLLPQLMKHLIKRFPKVHFEIEITNSHESLEQVAKHESDFGFIEKPLETSGVQRYSLM
                     EDQLVIAGDPKSKLWLVREANSGVFHYTQRYFEEMNIQDKKMIVKSNDVIVALLKEGI
                     GRSILSKRSVPENVPMTPLNFHRYFYFIQRTNLVSDQLLEIAEEILRYNESTETSHSE
                     ENLSW"
     gene            25720..26685
                     /locus_tag="LLC22_000124"
     CDS             25720..26685
                     /locus_tag="LLC22_000124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TDT family transporter"
                     /protein_id="HBK5433434.1"
                     /translation="MKNFLKIIPIPICGLILGLASLGNLFKDYHHVALGNLTGGISMI
                     LMIFIFVKLFILFEHTKQTLHDPIIASVSPTFTMSLMVICTYFVSYESIAPIVKFIWL
                     CAVIFQVILVFYFNYHHVIKADLSIEAIYPSWFIIYVGFGVITVTAGNFFPLIGKIFF
                     WISLICYAFLLPIIIKRVFFVRNMAHPTRPLITIVAAPGSLCLTGYLKNFAEPNFYLV
                     VALFALSQVLYFVVLSMLPRLFKLRFYPSYAAFTFPLVISATAIFTTVHYFNSLGIYS
                     SVLDFLKVAECLFASVVVFYVLAHYVRFLIKEHSKHGKFVSKKIA"
     gene            27062..28105
                     /locus_tag="LLC22_000125"
     CDS             27062..28105
                     /locus_tag="LLC22_000125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative sulfate exporter family transporter"
                     /protein_id="HBK5433435.1"
                     /translation="MKSLSHPIKSVKDSAVREILPGLLLSFAIAAFSRLLAIYLPQLG
                     GATIAILLGILLGNTFFKQPVLAIGTKFAESKLLEFSVFLLGATVTAQTIAQIGVKGI
                     VFVLLQMSVTIIGAYLIGKKLQFSDTSSLMMAGGNAVCGSSAIASIAPSIHAKEEEKG
                     QIITLVNLLGTVMMLTLPFLGLQLFGGNLIEKSALLGGTLQSVGQVVAGASLLDNSVV
                     EFAMLFKILRIMMLVVVVYLFEKFMHKKQPALFETPTDTQKKRKLPLPWYVLGFVIFC
                     LVNSLFSLPVVIDQSAHFISSWFEITALAAIGLRLDFAKFMKEGTRFLSYGLAVGLLQ
                     TVMALLFIWLIKV"
     gene            complement(28167..28631)
                     /locus_tag="LLC22_000126"
     CDS             complement(28167..28631)
                     /locus_tag="LLC22_000126"
                     /EC_number="2.1.1.63"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylated-DNA--[protein]-cysteine
                     S-methyltransferase"
                     /protein_id="HBK5433436.1"
                     /translation="MKIHTPIGFLWLDADESGLTAVSFQPISESESANQRILTRTQEQ
                     FEEYFAGKRKEFDVPLSIKRGTPFQQNVWKALSTIPYGEIRTYKEVAVAVDSPKAVRA
                     IGQANRTNPLPIVIPCHRVIGQNGKLTGYMGNAIDGVEIKRQLLLLEGYLQN"
     gene            28877..29824
                     /locus_tag="LLC22_000127"
     CDS             28877..29824
                     /locus_tag="LLC22_000127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5433437.1"
                     /translation="MKVSIVVPCFNEEKTVPLFFDEVEKFKGAHEFEYLFIDDGSKDG
                     TLAAIKKLASAYPYVRFVSFSRNFGKEAALYAGLQASTGDLVTVMDVDLQDPPELLPE
                     MINRITTSDIDCVGTRRSTREGEPAIRSFFAKKFYQLINKISDTEMVDGARDFRLMTR
                     QMVDAVLELTEYNRFSKGLFSWVGFKTEYISYENRERVAGETSWSFWKLFNYSIDGIV
                     NFSDAPLTIASFIGALSCVGSGIAILFIILRALLFGDPTSGWPSMVSIFLFIGGIQLL
                     CLGIIGKYIGKIFLETKQRPVYIIRETEKVKPNELKPHQ"
     gene            complement(30035..32107)
                     /locus_tag="LLC22_000128"
     CDS             complement(30035..32107)
                     /locus_tag="LLC22_000128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK5433438.1"
                     /translation="MKQLILAEKPSVAKDLSKVLGANQKHKNYYEGPKVIVTWALGHL
                     LGLKMPEDLNKEWQSWQMDTLPMIPKKLGIKPLPKTGHQLKAIKQLAQRKDVSEAVIA
                     TDAGREGELVARWILEYVHFNKPVKRLWISSQTDKAIKTGFKQLRPAKEYDALYESAL
                     ARAKADWLVGLNVTRALTVKYADNLSAGRVQTPTLALVRDQEKKIEQFRPQTYFTITL
                     QAGKEQAKMLQKNQFALKTQEEAQKLVQLISTSKGTVTEVQEKLKTESAPLPYDLTEI
                     QREANQRYGYSAKKTLSLVQSLYETHKIVTYPRTDSKYLTNDMKSTMKERLQAVSDFA
                     PEVKQYLKNGAIVQQTKVFQDSKVTDHHALLPTENRARYEKLSNEERKIYQMIVSRFL
                     GLFAQPHKVSQTKVTVEFGKERFIFRQNRVVQAGWKGETETETETVKWEKGMRINPDF
                     AIKKELSAPPKPLSEASLLGQMEKYSLGTPATRAEIIEKLIKSELMERTPQGLQVSPK
                     GKQLLVLVNPSLVTPDLTESWEKDLEAIAAGKKQAGTFLNGIEKETKRLVNEIKSSKQ
                     EYQDFSITQKKCPECGANLREKNTRDGKIYVCTNSDCNYRRRKDPKVSNHRCPQCHRK
                     MEIIEGKNGAYFRCKYDGTTEKLLDKKEQKKKMTKHEERRLLKKYAQAEEPEESPLAA
                     ALKAAMKK"
     gene            complement(32040..32417)
                     /locus_tag="LLC22_000129"
     CDS             complement(32040..32417)
                     /locus_tag="LLC22_000129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1033 family protein"
                     /protein_id="HBK5433439.1"
                     /translation="MYQVITMFGDNEPWWFFEDWEEDIEEEETFESFEEARQAYEKQW
                     NEIHQNYEYINAKSNFLSAFWNDGDERWCEECDDDLQQYKGLALLKNHQPITVESRKE
                     FYETTNSSGKTKRCERPKQGAWC"
     gene            complement(32546..33124)
                     /locus_tag="LLC22_000130"
     CDS             complement(32546..33124)
                     /locus_tag="LLC22_000130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5433440.1"
                     /translation="MRGNMEMKKRNLSQEKIIDCFRELAEEMDVQQITFQHLAKRLDI
                     KAPSLYNHFKNIRDVKTALTAKLLQELNDQLRRALVGKSGQEALQIYAETYRSFAFSN
                     QAVYELLISVPHTNEAVLLDGIHETNQIILQIFEAFQLTKEEKVHRSRELRSMIHGYL
                     SLRFLGYFTKEPTIDPEDSYFWMINNFIATLP"
     gene            33256..34548
                     /locus_tag="LLC22_000131"
     CDS             33256..34548
                     /locus_tag="LLC22_000131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBK5433441.1"
                     /translation="MAARIKEKLFRKRETWEQNLFVLWFGTFMAGIGFSLVMPFMSLY
                     IDTLGNYSTSQLNFWSGLTFSSTFLVTTLISPWWGKLADQKGRKLMLLRASLGMAIVI
                     SLMGCVTSVYQLVALRLLQGIFSGYISNATALVATGTPKEKSGQVLGTLATGSVTGTL
                     LGPLLGGISASAFGYRPTFFITGIILFFVFLLSLFFVHEKFVPVKKENMVSAKQIFKD
                     LKYPHVVIGMFVTTMIIQASNNSISPIISLYIRQLLHGHGNVTLISGIIASIPGIATL
                     IAAPRFGRLGDKIGSERILAIGLGFAILVYIPMAFVTNVWQLAALRFLIGISDACLLP
                     AVQALITKYSPHQAAGRIFSYNQSFQATGNVVGPMIGSSVSSAFGYRGVFLSTSLLVL
                     VNFLLVRHNTQEIHQQETAEEKASGVSIASGHSPSHRQ"
     gene            complement(34608..35726)
                     /locus_tag="LLC22_000132"
     CDS             complement(34608..35726)
                     /locus_tag="LLC22_000132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase"
                     /protein_id="HBK5433442.1"
                     /translation="MKIANFGVEEWLNKWEKKAVYDIAQSSIEALTLDELVGLDGTSV
                     SKFFEKRKNEPLDYGWIEGSDVFKQEVASLYQTVDPENILQTNGATGANLLALYALVE
                     AGDHVVSMLPTYQQLYDIPKSLGAAVDFVHLKEEEDWQFDLEQLEALVKPETKIICLN
                     SANNPTGTLLDRKTLEKIAEIARTVDAYVLIDEVYAPLTDKGEFLSIVDVYEKGIATN
                     SLSKTYSIPGIRIGWTATGPELAEVFRKYRDYTMICGGVLSDDLAVHALKNKEKILAR
                     NKKIITENLVILKQWVANEPKVELVAPNYVSTSFIKLAIEEDDQTFCINLLEETGVLL
                     VPGSAFDLPKHARLGYCCKKETLEKGLFLLSEFLKKQA"
     gene            complement(35740..37161)
                     /gene="arcD"
                     /locus_tag="LLC22_000133"
     CDS             complement(35740..37161)
                     /gene="arcD"
                     /locus_tag="LLC22_000133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine-ornithine antiporter"
                     /protein_id="HBK5433443.1"
                     /translation="MEKKSTGISKWGLVALVVSSSIGSGVFGITSDLASSAAPGPAIL
                     SWIIVGIGILALVLSLNHLGEKRPDLDGGIFGYAEASFGKLGGFISGWGYWLSAWLGN
                     VAFATMLMSAMGEFFPIFKGGQNVPSILFASIFIWGLTLLVNNGVEGASVINTIVTIC
                     KLVPLFLFLIFVFIAFKVNIFTADFWGNVSDNLVNGTGQQGTIWLQIKGCLMVMMWVF
                     VGIEGASVLANRAKKRSEAQQASIIGLLCLLFIYILASILPYGVLSQEELATISQPAM
                     ANILKGIVGNWGAALINIGLIISIIGSWLSWTMLPAETTMLMARDGLLPKGWGKTNKK
                     NAPTYSLVVTAILTNLFLLTFLVTDYAYQFAYSLCTAAILICYLLVGIYQVQFSLKEG
                     IKKQVVIGGIAVVFELMGIILAGFSYVLLCSIAYLPGFCFYWIACRETKHQITGKEKV
                     MIGLICVAALLSIGLLAVGWIKI"
     gene            complement(37407..38528)
                     /gene="mnmA"
                     /locus_tag="LLC22_000134"
     CDS             complement(37407..38528)
                     /gene="mnmA"
                     /locus_tag="LLC22_000134"
                     /EC_number="2.8.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 2-thiouridine(34) synthase MnmA"
                     /protein_id="HBK5433444.1"
                     /translation="MTDNSKTRVVVGMSGGVDSSVTALLLKEQGYDVIGIFMKNWDDT
                     DENGVCTATEDYKDVAKVAAQIGIPYYSVNFEKEYWDRVFEYFLAEYRAGRTPNPDVM
                     CNKEIKFKAFLDYAMDLGADYVATGHYAQVTRDENGVVHMLRGVDNNKDQTYFLSQLS
                     QEQLSKTMFPLGGMEKSEVRAIAERAGLATAKKKDSTGICFIGEKNFKQFLSNYLPAK
                     KGNMVTLDGEVKGQHAGLMYYTIGQRQGLGIGGGGDSQEPWFVVGKDLATNTLYVGQG
                     FHHPALYATSLDASEIHFTTNEPMPKEFKCTAKFRYRQQDVPVTVRLLDDNRAEVVFD
                     EPVRAITPGQAVVFYDGMECLGGGLIDHAYQETKVLQYV"
     gene            38932..39531
                     /locus_tag="LLC22_000135"
     CDS             38932..39531
                     /locus_tag="LLC22_000135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK5433445.1"
                     /translation="MNYFISDMHFFHEHLLGKNDFAPRLFANVDEMNQQLITSWNAVI
                     KETDHVYHLGDLAMHPQYEKANAEILELVTQLQGTIHLIKGNHDSRAFFRYLEKNDPR
                     LTDGSPKFYFYDVGAIVKFDHQQYYLTHYPMLLGPNDTIRNLHGHIHHYSVPIENDVN
                     VGVDAPERELLKEKLPFGTPLSEQQIKEIYEAKRKYDRS"
     gene            complement(39669..40955)
                     /gene="efmA"
                     /locus_tag="LLC22_000136"
     CDS             complement(39669..40955)
                     /gene="efmA"
                     /locus_tag="LLC22_000136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291207.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter EfmA"
                     /protein_id="HBK5433446.1"
                     /translation="MENEQSVVLTNWKRNYLFFLSGQFLSGITSMVVQYAIIWYLTRE
                     TGSATILSFATLLGMIPMVLLSPFVGPLVDRWDKKALLIVTDIIVAIFALILAVVGTI
                     SESFPIWLVFVSLFMRSVAQTFQMPTIQSIMPTIVPSSHITRTNGQLGMVQSANFIIA
                     PALGAALFSVVPVNYLILLDVLGAVFGVGLLIFVKIPKVSPEILEVPLTIFKDAKFGL
                     QQLMDNKGLWYITINGAFVMLLFMPAISLYPLMTLDYFGGSVGQAGAVEVVYAVGMLL
                     GGALISFIGTWKDRMKPIIIAYIIMGLTIGASGLVPNDSQGFLYFLILNAGAGCATPY
                     FNTLLMAMIQQSYESNVLGRVLGNFNSLMNLAGPIGLLFAGPLADRLGVEKMFLFSGI
                     GILLCGIVLFLTSAARNYDKELQKKLVKEHHEQKDE"
     gene            complement(41226..41570)
                     /locus_tag="LLC22_000137"
     CDS             complement(41226..41570)
                     /locus_tag="LLC22_000137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1831 domain-containing protein"
                     /protein_id="HBK5433447.1"
                     /translation="MAFETTATVLGAPISYRLHPDAKRYTLRDNGFTETNGGNYQLIR
                     PLDATPQSKEGFKLKITVSKDIQTLKMSITTANGLKAVNIFKDPKQKMSQDKFYFLMD
                     GMISRGLFEKVE"
     gene            complement(41707..42852)
                     /locus_tag="LLC22_000138"
     CDS             complement(41707..42852)
                     /locus_tag="LLC22_000138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK5433448.1"
                     /translation="MNEVKTIYLDHAATTPMHPQVIEAMTAIMQDTFGNPSSIHGFGR
                     HAHEKLETARQIIADSLQAKPHEIIFNSGGTEGDNTAILETAFSRQKEGRHLITTAIE
                     HPAVLNTMKYLETKGFDVTYLPVDEKGNLSIEEVKKALREDTILVSVMYGNNEIGNLM
                     PIKEIGELLADHPAYFHTDAVQAYGNQTIHPEELGIDLLSISAHKINGPKGVGFLYKR
                     DGVNIPALLLGGEQEEKRRAGTENLAGIWGMAKAVELLSPEEREARNNKYKGFQQLIL
                     DTLEANEIPYQVNGDLTNKLPHVLNLRLIGEANDLLLMKLDLNGVAISTGSACTAGNI
                     EPSHVLEAMYGEDTPILKESIRISFGLGNTEDDIQYFLDQLVRAVKK"
     gene            complement(43032..44006)
                     /locus_tag="LLC22_000139"
     CDS             complement(43032..44006)
                     /locus_tag="LLC22_000139"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBK5433449.1"
                     /translation="MSNKYQDDTLKIFSLNGNRPLAEKIAKVFGTELGKSVVKQFSDG
                     EISINIEESIRGDHVYIVQSTNAPVNDYYMELLIMIDAMKRASAKTINVVLPYYGYAR
                     QDRTAKPHEPITAKLIANLIEEAGATRVLTLDLHTVQVQGFFDIPVDNLFTMPLFAHY
                     YRQLGLTGDDIVVVSPKNSGVQRARSLSEYLNSTLAIVDHADDASTEGGYVIGDVQGK
                     TCIMVDDILNTGATLARAANVLKENGAKEVYACASHGLLSDHAKSILDNAPIKDICIT
                     DSVFTEENRHPENLTIVTCSELMGEAVKRIHENTPMSPLFRLEEKEFE"
     gene            complement(44086..44961)
                     /locus_tag="LLC22_000140"
     CDS             complement(44086..44961)
                     /locus_tag="LLC22_000140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoamide dehydrogenase"
                     /protein_id="HBK5433450.1"
                     /translation="MKKRRRSQLNQVVDKPLYFKVDKKIKKLASTQQLQSRKSKLLFL
                     ALVFEDQSYVIIDQSGHPVEYSPAKYTYQEGLSCKKWKLINEEPIELSRWINRKEDIP
                     VLIEEKRSGKELANCWVGLPEERFLRYKKWATPSGYLCGTYAAAVLLAYYQDYRKGWM
                     LPNEIRKKNTADSLVLTKALRSQIQPLGLPTIPFQVSTGISSFLKKNGNHERARATLL
                     GSWQRATKRIREGKPVMIGILKVLGSTYGNHWVTAYAYFETETGERYYKVHDNWGDYH
                     KVIPASWSNGTVSLP"
     gene            45091..46998
                     /locus_tag="LLC22_000141"
     CDS             45091..46998
                     /locus_tag="LLC22_000141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M13 family peptidase"
                     /protein_id="HBK5433451.1"
                     /translation="MNKERLKQDFYEAVNEEWQKTAKIPADKPATGGFQDLVDGIDQL
                     LMGETDDLLAHPEKVSSEKMKHFLAYYQLANDYDRRNELHAQPLQPIIEKVESLQSFD
                     ELNKQFPEWLLDTLPLPFNLDVDADMKNAQTNAFFAYPPSLFLPDKTYYASDHPNGAQ
                     LIGVFFDMAVQLLELAGKEKSQAEAITEQAVQFDKLIAPHVKSAEENADYSKMYNPQS
                     FDTFIKYTDKLDLKKLVTGLIGTTPDKVIVTDPVYFDHLNDILTEAHFPLFKSWMIIK
                     TVRSLSGYLSEEFRQVSGIYSRVLSGTDEAMPQKKAAYYLASGQFDQVVGDYYGKKYF
                     GEAAKKDVEQMVKKMIAVYKKRLEENDWLGDATKEKAVIKLNNLGIQVGYPDKIPALF
                     DQFKTVPADQGGTLLSNTLVFSKLTLKDRFSKWNKPVDRSEWEMSADTVNAYYHPFRN
                     VIVFPAAILQAPFYSLEQSSSANYGGIGAVIAHEISHAFDNNGALFDEYGNLNNWWTE
                     EDLTQFQNKAQAMIEEFDGLPFADGKVNGKLTVSENIADAGGLSCALEAAKTESDLSI
                     EEFFVNWATIWRTKAKKEYQQLLLQIDVHAPAKLRANVQPKNLDEFYETFGITEQDAM
                     YLAPEKRVRIW"
     gene            complement(47539..50817)
                     /locus_tag="LLC22_000142"
     CDS             complement(47539..50817)
                     /locus_tag="LLC22_000142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1565 domain-containing protein"
                     /protein_id="HBK5433452.1"
                     /translation="MLKKRIKYSALMMNLLMLSTPVLISVVEVAANEQQSVNEENAHV
                     NIEGMSTMEEIPRTSEDMDTEEGNDPMMKESENEKTKKQSEEANEEWKGVVFGESTSA
                     SRYAIEPLEDGVRLSSTNNGGKFQSSGSDGMTYYYQAIPKDINFRMRATIEIESWTYT
                     NAQEGFALMVRDAVPKNHLFGQAFYSNSFAILGSRIEYVWDSDRQEVVNTSGSKYTMR
                     LGLGTRAITGISSEDPQAAPAPGSVSVETTPLETSAGFLEKETGSYNIFGNGHGNLFP
                     ATNSITKLDVEMKKTNTGLEAYYYDPETGEEMASDIMYDWEKLYASDESVIYAGFAAA
                     RNMTIKVEGIEVAYSDPATDPPGQERPTRLIDPIYTVTSSNHSGNQDHTMSFRANADG
                     LLTIKNKATGEVLKNAKNLAITANREFDYQTKLMEGTNEFTFSFTPDKNYPPEEYVEM
                     TSYETKEILHTVDYRKPKYSTVYVTPEGSDAGNGSRQNPLSLTQALRYAYAGQTIVMA
                     PGTYSFERGLTIPKGVNGTRENPIQLIAEKNPENKRPVLDFKGTGNGMTLFSHYWGLR
                     GFDITNSAAMQKGLQISGNHNLIEEIHAYRNGNTGIQISGSSNDPFEAWPAHNLVKNC
                     TSFENADPGFEDADGFAAKLTIGEGNVFDGCIAYHNADDGWDLFAKNETGSIGKVIIK
                     NSVAYRNGWVPGIEGEGNGNGFKMGGSSLTGPHELINSLSFENLAKGIDSNSGTDIIV
                     NSSTSFNNGSYNVALYTSSAGNTDYHASGILSFRTENLEMREQIRPLNQNEDQIYHSL
                     NYYWNEREKQSENTLGHTISKDWIESLNTCSKEGQQPVTRYENGSIHVHGLMQIKPGN
                     RQTEKERVDGLPLSVGAIFDGETSPSSEYPEYAIVQEPNQTKPNEQNNPIIIQEANGV
                     AENAEGNIIELKPFTVFVSTFTPNQGTPVFEDMRYFPEKIQIVETQSSAQFSNHTAIF
                     SAPSKGEYTLEVTYRSEIFDGEKWSAHTESVTQQKAITVRETADVPPENDKPERENPG
                     NESPNGKPNGKPSHPDRTAKESEKNGTQGLPKTGEFNNPLLALAGGILLIGVVVYVMK
                     QRKK"
     gene            complement(51088..51633)
                     /locus_tag="LLC22_000143"
     CDS             complement(51088..51633)
                     /locus_tag="LLC22_000143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5433453.1"
                     /translation="MNALISIDYTYDFVAEDGKLTTGTAGQVIEKKLTAHTKKFIDQK
                     DFVVFAIDAHDPKDSFHPENRLFPPHNVIGTGGRELYGSLKSLYQDYEQEENVYWIDK
                     RHYSAFSGTDLDIRLRERQITDIYLTGVCTDICVLHTAVDAYNLGYKLHIFKDAVASF
                     DPVGHEWALRHFESTLGAEIL"
     gene            complement(51645..52337)
                     /locus_tag="LLC22_000144"
     CDS             complement(51645..52337)
                     /locus_tag="LLC22_000144"
                     /EC_number="3.2.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5'-methylthioadenosine/adenosylhomocysteine
                     nucleosidase"
                     /protein_id="HBK5433454.1"
                     /translation="MKIGIIGAMEEEVKILRENLSEPLSWERAGALFISGSLGNHEVI
                     VVRSGIGKVLASITTSLLIQQYGVNMVINTGSAGGIGEGLQVGDIVISDKVAYFDADA
                     TGFGYNPGQLPGMPLYYEASTYLRSEMVKAAKATNLNAKEGLIVTGDTFVDSPDKIKE
                     ILTNFPEALACEMEGAAVGQTARQFNIPFLIVRAMSDTADHSATQSFDEFIEDAGKRS
                     AEMVIEFVKHLV"
     gene            complement(52356..52640)
                     /locus_tag="LLC22_000145"
     CDS             complement(52356..52640)
                     /locus_tag="LLC22_000145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433455.1"
                     /translation="MAKGPLITRSELRKRQQAQASESLKKQRKAETAYQQEEKKIASF
                     YRKESKKNKPITKTRISEREKTTKWNSFLMKSLIIVILMLCVVFLAIAFI"
     gene            complement(52653..53216)
                     /locus_tag="LLC22_000146"
     CDS             complement(52653..53216)
                     /locus_tag="LLC22_000146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK5433456.1"
                     /translation="MLNNEQFEEKTISRKEIYSGKIIDVAVDEVRLPDGGTSKRELVF
                     HPGGVGIIAFDEQDRLLLVKQFRKPLEKVILEIPAGKIDPGEGQNPEMTAARELEEET
                     GYRAKSLSHLTSMYLSPGFANEVLHIYHAQGVEKVENPLAQDEDEVLELYHLTLEEAQ
                     QAMKDQLICDAKTIYAIQYWELLTKGK"
     gene            53444..54106
                     /locus_tag="LLC22_000147"
     CDS             53444..54106
                     /locus_tag="LLC22_000147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-bromo-4-chloroindolyl phosphate hydrolysis
                     family protein"
                     /protein_id="HBK5433457.1"
                     /translation="MIKRNWPWLLALVLLFLFVRNNSFSFVLGLLLIGVVLVLWGLFG
                     SRRKKGKQEEIPALTDELETHYEKSGMTANEISFFRQTMNQTKNEINQLQMNMQQTAK
                     LKAIDLRHDPVKAAKALFKELVKEPNRLHEASQFLYTHLPNLVDLTNKYNEINDHEIK
                     NKQTYEKLEESAQIIDQLSALIAQDYQKFVAEDLDDIDVEISVAKQSLKRDNKYEPEQ
                     KD"
     gene            54230..55426
                     /locus_tag="LLC22_000148"
     CDS             54230..55426
                     /locus_tag="LLC22_000148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxic anion resistance protein"
                     /protein_id="HBK5433458.1"
                     /translation="MDHKPTETKDVTPVNDTLEDLLNNPFSTPTDTLTTSQQAEIDQL
                     QEQQTAARLIDKLPAERQEQAKQLAAKIDANDAQSVISYGSAAQAKLSEFSQSMLNHV
                     QAQDIGPVGDSLTELMYRLQEANPDELRAGEGNIFQRVFGKVKQSIYEVTAKYQKIGA
                     QIDKISVKLDKEKDGLLKDNLMLEQLYQKNKDYFDALNIYIAAGELKMEELQTTIIPE
                     AMKRAEETGDQMDVQIANDYTQFLDRLDKRTHDLRLARQITIQQAPQIRLIQNTNQAL
                     AEKIQASIATAIPLWKNQVVIALTLLRQKDAVTAQRQVSETTNDLLKKNSEMLKISAI
                     ETAKENERGIVDIETLQTTQNDLIETIQETLRIQKEGKEKRRHAEVELGHMEEDLKQK
                     LLDLTQ"
     gene            complement(55527..56903)
                     /locus_tag="LLC22_000149"
     CDS             complement(55527..56903)
                     /locus_tag="LLC22_000149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631307.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5433459.1"
                     /translation="MDLFRKKEINLNHTSEMKKELKTSDLIMLGIGAIIGTGIFVVTG
                     VAANQNAGPALSLSFVLAAIVVILSGLSFAEFASRVPVIGGPYAYLYVVFGEFAAWLT
                     GWLLIGEFLLAVSSVASGWSGYMQGFLKSLGAELPQALTGGYNPENGTYIDLIAVLVV
                     IFVTYIVSLEAKKALRLNNAMVYVKFGIIALFIIVGIFFVKPDNWQPFMPFGFSGVLD
                     GAALVFFAFLGFDAVAMAAEEVKNPQKDVPRGIIGSILIATVLYIIVTLILTGIVPYT
                     ELGVNDPVAFAMRYVGHGTVGAVIAVGAILTLLTVTISMMYSLARLLFAVSKDGLLPK
                     FMTEIDQKHRTPKKATYAAGVAAVFFAGFFPLNVLAELTNIMALAYLMLVSLGLLKLR
                     KMFGKPKAGEFKVPFVPLLPIVSILTCIVLMLRLQTVTWIVFGIVMVIGLIIYFGYGY
                     GHSKMNEK"
     gene            complement(56940..57806)
                     /locus_tag="LLC22_000150"
     CDS             complement(56940..57806)
                     /locus_tag="LLC22_000150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose transporter GlcU"
                     /protein_id="HBK5433460.1"
                     /translation="MEILIALVPMLAWGSIGLVSGKIGGDANQQTLGMTIGAFLFSLV
                     VFFVVSPVITPWIFLIGFLSGLAWSVGQNGQFHGMKYMGVSVGLPLSTGFQLILNTIA
                     GAVFFHEWTQTKDYVYGIIALALLVSGAYLTARQDDEGKIDTDNKMLDFGKGFRALIF
                     STIGYGVYTIIVNWANLDAMSIILPQSIGMILGASFFAFRKVKVDQFVWKNMICGLLW
                     GLGNICMLLTVKSLGLAVGFSLSQMGIIISTLGGIFILGERKTKKELIYVIVGCLLVI
                     LGGILLGYMKTV"
     gene            complement(57895..58920)
                     /locus_tag="LLC22_000151"
     CDS             complement(57895..58920)
                     /locus_tag="LLC22_000151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5433461.1"
                     /translation="MNFFKYLKDQWTLILGWLFFIALTIFVMWLAPNIKVDLSTIAYL
                     ALIEGVFLIFYLLGGYLSKRRWWGKLADIQKTSPLQNYLSGGRTEEEKLVEEYINQLI
                     REHQEVMQSAISNQQDQKDYIDSWVHEIKVPLSASKLLVRSIEFDIDDQKYTLLENEL
                     SKIDEYVEQVLYYARLDSFSRDYLIQEYGLKGIIQPVIRSQANYFIQKNIRYEIVGED
                     HTVLTDAKWIAFIFNQLLSNAIKYTPDHGNIIVSIEKEAQGVSLSVKDSGIGIPAEDL
                     KRIFDKGFTGRNGRLSKTHSTGLGLYLAKNLAEKLGIHLTAESTEGKGTTMTLFFPIL
                     NFYNEKR"
     gene            complement(58938..59612)
                     /locus_tag="LLC22_000152"
     CDS             complement(58938..59612)
                     /locus_tag="LLC22_000152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5433462.1"
                     /translation="MAKIMVVEDEEIIRQLIMEELEKWQFETFGTTDFNQVFSDFERE
                     EPQLVLLDINLPVLDGYYWCQKIREVSKVPIIFISSRNTNMDMIMAMNMGADDFVTKH
                     FQIDVLIAKINALLRRSYNYTELSSEMMSHNGITLNVDNGSMEINGEIIDLSKNEYRL
                     LFILMKHNGKILSREKLLRALWDDERFVDDNTLTVNINRLRRKIEQAGIQGYIETKVG
                     QGYIVP"
     gene            complement(59796..60689)
                     /locus_tag="LLC22_000153"
     CDS             complement(59796..60689)
                     /locus_tag="LLC22_000153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5433463.1"
                     /translation="MKKKIGNRPQTQISLLLQLFMAVMFLAGAAVFTYPFLADALSNY
                     LDQRRIENYQKQLERDKEEKHEQQLAVHEKKNQTLAHTSVIPGMGQVKDPFEQAVRNV
                     QNPGKEYYEQHMIGAIYIPKINVSLPLFDETNDLLLDRGATVLQGTSFPTGGESTHSV
                     ITAHSGIAEKKLFTDLEEMEQDDRFYLEVYGRMLAYEVVEKIVVLPTKTNTLAIREKQ
                     DLVTLITCTPYTVNTHRLLVTGRRVPFTEEVSSKIEQTKKYHLYRLLILLLGILLVLT
                     LFGYWCYRKFKRQKQRKKNNR"
     gene            complement(60763..62460)
                     /locus_tag="LLC22_000154"
     CDS             complement(60763..62460)
                     /locus_tag="LLC22_000154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBK5433464.1"
                     /translation="MNKKMIVTGMSVLLLVTAGIGIFGNGKLVKAEEVAQKPSEVTIT
                     LHKKGFSSVPEERPNSGLVSTDFGEENIPGVDFDLFDVTEVYYDLIRDNPLTPEREDG
                     LNSAEAIEWIQKRHTESWFLKYRLTSIDKQTTNEAGEAVFSTVQVTEEAPSSRDKVYL
                     FLETYSPAHISRIASPMVVMMPVMMPDMVDGVWDGSTWKDTYNTDVHLYPKNEIREAD
                     KQMNVEESDLRQVTIINEAGEQETISYIDLERGKTASYTITAPIPYFIDSVLENGSAV
                     IKNYKITDTPTVGLTYYDQEIEVRAGETILTKGQDYIVEVVSNGFVVTILTEENGVAK
                     VDTLGRLADARGGDLTITYNLKVSTELEADDFHNNTAVIEIGRNDEFDYEEGVEPPEK
                     VTTGGRKFEKYDASSSELLKDARFELWNEDRSEYAIFYKGESPLAVYESGADRIEWAT
                     SGQATEFVADGNGYFEVQGLDYGTYQMKETMAPEGYVLPTGEAAFTEFIISYGSYNEE
                     IQIVGVENPGPERVPNMKRGSLPATGGNGLLAFLLIGISLMIGAYSWYRKSKMKSEV"
     gene            complement(62453..63766)
                     /locus_tag="LLC22_000155"
     CDS             complement(62453..63766)
                     /locus_tag="LLC22_000155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBK5433465.1"
                     /translation="MKKLLCLMLQLLVLLPLAAVLLPHAMSAEESGEDVVEFVLHKRM
                     IRDIDYNDQFEYHENDGLAISEEAGETADIISQTVPLNGATFAIYDMTDYYHEKKAAE
                     NMTPKEFVQQIAETNRNNIRQLITEERLVQIGTSVTTGKDTVGGLGDGIARIKAPKKN
                     QDRDAVYLIFEESIDPEVGLDVDIDQTAIPIAAILPIYHPTESTEELQEIHIYPKNVG
                     YLRDPYFFKYGRQRGTTEKGKPLEGAVFALYQMIEGGKYYLDMAPANDLKNQWIKPAD
                     NDPLNDKNVSKFISDKEGLVTTGQRFLPSGTYYFEELKGVEGYEMDEASKRIEVIIPE
                     FWVDAKGQPQYVVVNGQEMAELESGKVPVSAYESATPRVYNETVKETTDKPKEPSGPS
                     NPGQSGKWSVFPQTNEARTLISLLGILLLLGAVLLIKKERGEKNE"
     gene            complement(63766..67284)
                     /locus_tag="LLC22_000156"
     CDS             complement(63766..67284)
                     /locus_tag="LLC22_000156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBK5433466.1"
                     /translation="MDYNGAYIKKWVEPVLPSSTASDLHPEDATTLYNVYLDVIGGEK
                     KEISPIDIVFVLDKSASMSELTAGTNSQTKNAALIEAVNEMSKDLLSDPSLDIRIGMV
                     NFYHNSTAINNHEQISSDIFPLTNDINRLTGSENTALNRTPIGGTPLTLGLKNGYETL
                     YKDNGGENRNPEKILIVVGDGTPTFSYAPIQSSYRTSTNGAWSNWTVMEDKIAEDNDV
                     LFRNFEEFSGNTSNAGFTHPVTYASDFNRPEDEVNVHYRYGEVKEGDNKATHWVGDGS
                     SNNNTNGSPTSQEKSSAINTVAYHHWLKNKYQENPPSIFSIGLGIDGNVSGRQRLDAI
                     GRNVLKNIADLEEDGVTPRYYNANNKNDIVTALEDISSTFKRTIQQATLYDETGFNVS
                     PFGAGRSADIQFYHLDPGENGMKYQEPEIWDEERHGQAPPEVVATPTTYVGRENQAYK
                     FSPISLGEGEMVRIKYQVKLDAGAQDGNFCTVNNMAYIQNLEDYENDITTGRMYFPSS
                     SIRYEHKGRNFQVSKKGQNGEPLAGVEFALYDQNPESGEAEPIETSKTTTDGIAIFET
                     KMPILGDETGAVSDIFWIREIAGPPRYQLVDETYQFQIKKYAANEDEMLGHYELVDEY
                     TSGSRVGGPEGKDPNSYYEGEYHKLSVVQEPNIEGTEYDELYVKLEMRNEFKPIHMNI
                     NKLIEGSNMPINGAEFELYETDGNGLEIGYPVAKGLSGVNEVEEEKGRLTFYSVDEDG
                     KYVIVDGEKVIHPIGEPDSFVYKDSEETTNYAEYKIIESQNPEGFKEPDENDTWILRL
                     YDNAIGTIQLKQTGEENWQYLTYTTDEEDRLWVAFTAYNTFDYREIRVRKLDHEGHTL
                     DGAGFDIRKVGDSSFPLYRAYTGNPLEPEESKRLPGIGYFYSRAVGVEKYVDLNYDQP
                     LHLSIGEYEVSESVAPNGYRLSDQVFQFALNEEGKFIIEDTVIEDETAPLPEGYEIID
                     GVLQVTLEDELAPIDLELLKIDSMNSRRLEGAEFSIEKQNSAGEYEIIEGGLAPDPND
                     SSLFNASDLLEGVYRIKEVKSPDSYRKLPGYFILEISYREEPDIENDRVVPGKEAGTL
                     KVEISYYPNEEAETPDLQQELEYELLETNRIRLQLSVGNDPENPLPATGGSGRLFYIL
                     LAAFFMALAGAAYGLFVRQSKKEGAR"
     gene            complement(67577..68035)
                     /locus_tag="LLC22_000157"
     CDS             complement(67577..68035)
                     /locus_tag="LLC22_000157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5433467.1"
                     /translation="MKGLKLKLLQLVTVSLLFGPYFQSVYHMTTLDVAAESTETKEDE
                     VFLDEDYAKIEGKYIEKEETLEWHLAFEKKESANEGRIRLAIDAAAAGIGTVKNVRGT
                     GLSSYDEDGEDLKVETIDGQEWYVGKVYSKEAETGTLIFETEKIPDVNEG"
     gene            complement(68333..68851)
                     /locus_tag="LLC22_000158"
     CDS             complement(68333..68851)
                     /locus_tag="LLC22_000158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBK5433468.1"
                     /translation="MLRLIAKIDDSIINKFAKQRKTDSRKINFLKFISNISNGGFIWL
                     LLAAVLVLIPDTREYGLAILIGSLIYFFVGLLFIKKTTRRKRPYEKNRRLVLYTSKPK
                     TSSFPSGHTALAFLSVAALFELSPVAGILAFLFACLIAYSRIFLLLHYPTDILGGAIL
                     GSVIGILCAAVI"
     gene            complement(68853..69470)
                     /locus_tag="LLC22_000159"
     CDS             complement(68853..69470)
                     /locus_tag="LLC22_000159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBK5433469.1"
                     /translation="MMNRSIGKKANDYFLEIIEWIPRLIHLQLLWFLCVLPVFTLGTA
                     SRTVLYMIYHYKKNEEKKLGSLFWKKFRENFSFYGKQDSLASVYFLLLLIDYQIFRYW
                     GGGIGYTLMYTTLFLLLLSALLFSYKILLQLEQKEASWITAFFLFFNDFKSALFYLAG
                     TLILLVAFWFAGPIYFALLGFSFLFYFQVLLFIHRTQEKVLKKEE"
     gene            complement(69467..70321)
                     /locus_tag="LLC22_000160"
     CDS             complement(69467..70321)
                     /locus_tag="LLC22_000160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5433470.1"
                     /translation="MMDYFKKTSVNRQTKKILSYVLMTVIGIILIIPLLWMVFTSLKP
                     MEEIVRYPPTFFPEKIVWENYLDTIAAFPFWRYARNTLFITVLVVIGNVLSNSFIAYG
                     FAKLDFPGKKLMFALVLSTMMIPGFVTMIPQYVLFSKIGWVGTYLPLIVPSFFGNAFN
                     IFLMRQFYLSINNELIEAAEIDGANHLYIWSHLMLPLTKPALITIAINSFNAAWNDFL
                     GPLLYIQDQEKYTLQIGLQVFQNQATTQWNYLMAGATLVLIPTILLFFFAQRYFIEGM
                     DLTGGSKG"
     gene            complement(70318..71229)
                     /locus_tag="LLC22_000161"
     CDS             complement(70318..71229)
                     /locus_tag="LLC22_000161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5433471.1"
                     /translation="MKRLSIRKKKEARWAYLFISPFIIGFLVFMLGPMLFSVIGSFTD
                     YNLTSKMNFIGLANFKRMFVHDDLFWKSLYNTVYFVIFNVPLTTIFSVFLATVLNQKI
                     KGISVFRTAFYLPAVLSGVAVYILWMQLLSPSAGLINTFLGWFHIPGPAWLFDPQWTK
                     PALILMKIWSSGGAMLLYLATLQNVPRSLYESAEIDGAGVWGKFKSITLPLITPIIFY
                     DVITSTIGSFQIFQEAYVMTKNGTGGPANSLLFYNLHMWNKAFVAFDMGYAMAMSMIL
                     FLIVLVLTFVNLKLAPKWVYYSGGDGK"
     gene            complement(71270..72604)
                     /locus_tag="LLC22_000162"
     CDS             complement(71270..72604)
                     /locus_tag="LLC22_000162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5433472.1"
                     /translation="MKKLLFTGLLASSALFLLGGCGSSNASDASSSAANSSEKTSDGR
                     KNIDFWSFWGSGARKEAIEEIIEDFNQSQNEIHVNYKYQPWGDIWTKSLSAITAGNAP
                     DVIVQDINSVAQRAEAQQATNLSKYVEKDTSKDFYPQLWDTVEYEGDPYAIPFNTDTQ
                     VIFYNKKLFKEAGISEQDLPTTWDELEETARKLDKKEGKEFTRIGFYPLWNLGADVWA
                     LNADNGTSWFDKDEKVKIDTKNKVEALEWIQDWQDYYGKNTINKLEAEFGSGVSDPFI
                     SGLVAMRAQNINYYSSLMENAPDDFDFGVMQLPEKEEGSGHWSWGGGFVLEVPYGAKD
                     PEASYEFIKYLSSPEVQEKFGEKSFDIMASKTANENLVNNDNLTDKGKMIYQMADENF
                     KNTVITPVPLDAPDYTTLVNEQIDQILLGTKSPKEGLADAQKAVENLVKQNQ"
     gene            72812..73642
                     /locus_tag="LLC22_000163"
     CDS             72812..73642
                     /locus_tag="LLC22_000163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese catalase family protein"
                     /protein_id="HBK5433473.1"
                     /translation="MFRHQKELQFEAKPDRPNPLIAKYLQELIGGQYGEMSVAMQYLF
                     QGWSCRGEEKYKDMLMDIATEEIGHVEMLATMVARLLEGAPVEDQEAAMQKDPTIGAI
                     ISGMNPQHAIVAGLGPRPADSVGNPWSGAYIIASGNLLADFRANLNAESQGRLQVARI
                     YEMIDDRGVKDMLSVLLARDSYHQNLWECAVKELEEKEGSILVPSTFPRDKERKDIAY
                     DFYNFSEGDQSSEGSWASGKALDGEGEYQWLKEPKIEGAAPKLEPVTPKMYGTPPFKK
                     "
     gene            complement(73886..74204)
                     /locus_tag="LLC22_000164"
                     /pseudo
     CDS             complement(73886..74204)
                     /locus_tag="LLC22_000164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012028215.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(74326..74520)
                     /locus_tag="LLC22_000165"
     CDS             complement(74326..74520)
                     /locus_tag="LLC22_000165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433474.1"
                     /translation="MKTTLVLFYKKHPYFTLLINILLASVIGISVEYLINKDFIGSCF
                     YTALFLGLLEAFSIYKKSKK"
     gene            complement(75025..75210)
                     /locus_tag="LLC22_000166"
     CDS             complement(75025..75210)
                     /locus_tag="LLC22_000166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433475.1"
                     /translation="MSKNSKGFLTILLAFIGYMLVGLLKSYSNELLNFSTFINDTLVP
                     SLFFIVFFAVGYFIIKI"
     gene            complement(76060..76401)
                     /locus_tag="LLC22_000167"
     CDS             complement(76060..76401)
                     /locus_tag="LLC22_000167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBK5433476.1"
                     /translation="MSEERIYIPKKGDIVWIDFDPSVGKEIQKRRPGLVVSRYEFNRK
                     TMFSVICPITSTIKNLPTRYSLPEELDIKGQVIITQLKSLDFKERKLKKIENLPLQDM
                     AKIDQIIQYMF"
     gene            complement(76401..76631)
                     /locus_tag="LLC22_000168"
     CDS             complement(76401..76631)
                     /locus_tag="LLC22_000168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5433477.1"
                     /translation="MLVTKSRLQGSSVVVTLPSDNGKKPSENQEYIVVYSDDGTITLV
                     PKIEDPFSGGEEAEYYEKDEWEDLTPEGREIL"
     gene            76918..77256
                     /locus_tag="LLC22_000169"
     CDS             76918..77256
                     /locus_tag="LLC22_000169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433478.1"
                     /translation="MPDYKQKAGYSFCSDKFQLGKFTKLAGEEVSTVRIKECPLQIET
                     LVQRISTRQDFAIVEREIVAIFVEEGILHDPTHINVDKWQPLIYKFREYTTANQSLTL
                     NFRFQEFKES"
     gene            complement(77461..77700)
                     /locus_tag="LLC22_000170"
     CDS             complement(77461..77700)
                     /locus_tag="LLC22_000170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBK5433479.1"
                     /translation="MFSNKEKIVYIGGFYRSHQDEKMAESIIMTTEPNRTVAPIHDRM
                     PLVLTEEQIEPWVTDISFARKIITQQMPELVMEKV"
     gene            complement(77676..78023)
                     /locus_tag="LLC22_000171"
     CDS             complement(77676..78023)
                     /locus_tag="LLC22_000171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SOS response-associated peptidase family
                     protein"
                     /protein_id="HBK5433480.1"
                     /translation="MCGRYFFDLESELLQNYYREAQTKQPKQAAELAAGEVFPSNLVV
                     TLRKEEENILTPEIMKWGFTGFKKGQLMINARAETVEEKKTFHQPFLQNRCVFPMSGM
                     KKKTNLCFQIRKK"
     gene            complement(78755..79336)
                     /locus_tag="LLC22_000172"
     CDS             complement(78755..79336)
                     /locus_tag="LLC22_000172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5433481.1"
                     /translation="MKTKEKILEATKDLIYKKGYHETSIRDILAASDTGKGQFYYYFS
                     SKKEVCLAVIHAHMDVWQTELFEDILNAGKQPEEALEEMLDWIFADHETQITYHGCPV
                     GNLIIELSTVDEEYRLLLLELVNQWVKYTKQNILALSEEKLSDEEADRQAKALIAEIQ
                     GSILLLKVTQDLSLLRQNFQLVKERLLTSQKVL"
     gene            complement(79519..80145)
                     /locus_tag="LLC22_000173"
     CDS             complement(79519..80145)
                     /locus_tag="LLC22_000173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5433482.1"
                     /translation="MFNNKNTAVVLTDPQVEFLKPAGGGFGLTKDILEKYNTIENMIE
                     MVKQAKEKGYKLFISPHYFYPHDHKWQFGGAGEHMMLEQQMFARKSQYESVEEGSGAD
                     FIEELKPYLDENTIISSPHKIFGPESNDLALQLRKNGIDTVILGGMNGNLCSDSHMRE
                     LVESGFNVVVATDAIGAPGQEAMDAALTNFGFIADQVMTTEEVLEQLS"
     gene            complement(80167..81498)
                     /locus_tag="LLC22_000174"
     CDS             complement(80167..81498)
                     /locus_tag="LLC22_000174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-containing oxidoreductase"
                     /protein_id="HBK5433483.1"
                     /translation="MMEKYQNIVIGFGKGGKTLAKALASKGESVLVVEKSTRMYGGTC
                     INIGCIPSKSLIFNGERGIDFTEAVARKEKLTGMLRAKNYHMISDEATGTVMDGTARF
                     LSNHQIEVTNNGEKVIVEGERIFINTGSEPIILPIKGLNTSRYLIDSTQAMDQEQLPE
                     KLVIIGAGYIGLEFASMFNEYGSKVVVLDAHSEFLPREDEDIAQMILEDMTNAGIEFH
                     LGVSVDQVADQESTAAVTFTEDGQEVTIQASKVLAATGRKPSTASLGLENTDVKLTDR
                     GAIAVDEYLRTDADNIWAIGDVKGGLQFTYISLDDYRIIMDQLKGENKRTTNNRKAVP
                     YSVFITPTLSNVGLTEKQAKAQGVNYKLFKYMTSGVPKAQVLEDPKGVFKVLVDPETD
                     LILGASIYAEDSHEVINLISLAMNGKLPYTLLRDQIYSHPTMSEALNDVLK"
     gene            complement(81653..82054)
                     /locus_tag="LLC22_000175"
     CDS             complement(81653..82054)
                     /locus_tag="LLC22_000175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBK5433484.1"
                     /translation="MKKAYETAMINHGGRNGEVEEPNGSMHMKITPPGIHAEGTNPEQ
                     LFAAGYASCFNGAVQHMIKEAGMTAESTVKARVSLYNLDDGGYQIGVVFEVHIDGISE
                     EEAQKIAEDAHEFCPYSKATRGNIDVEVTIV"
     gene            complement(82140..82346)
                     /locus_tag="LLC22_000176"
     CDS             complement(82140..82346)
                     /locus_tag="LLC22_000176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433485.1"
                     /translation="MVTNMVIFLTVLVYGVNFLVYMYLKINHIKDYVEKIAIYFGTNM
                     TLLFTSSIFLFFGKIVEDGILVFE"
     gene            complement(82441..83943)
                     /locus_tag="LLC22_000177"
     CDS             complement(82441..83943)
                     /locus_tag="LLC22_000177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomannomutase/phosphoglucomutase"
                     /protein_id="HBK5433486.1"
                     /translation="MKDMKALQNGSDIRGIALPVEGYEVNLTTDMVKKIGWGLANWIK
                     KKKKSTDPNKKWTIGIGHDSRISGPALKEALIQSLKEQGIHVIDFELATTPAMFMSTQ
                     FEQFSCDAAVMLTASHLPYYYNGIKFFTSEGGAEKEDIAFILSQQQKIKSEQTGSVEK
                     ADLLTPYAQDLVTKIKKGIGTLESKPLNGWKIIVDAGNGAGGFFAEKVLNSLGADSTG
                     SQFLEPDGRFPNHIPNPDNKEAMESIKQAVLANEADLGIIFDTDVDRSAVVSASGTVI
                     NRNNLIAVLSTIVLKEHPGTRIVTNSPTSSHLQRFIEEKGGIQVRYISGYRNVINKAL
                     ELNRLGKDTQLAIETSGHAAFKENYFLDDGAYVIAKILMLLPELKRKGITLDEQIKEL
                     KQPVEVQEIRLKLFSDEPREQGNKILEEMKRLLEEEKGMNFDPENEEGIRYDLEEPYG
                     NGWFLIRLSLHEPLLVLQIENDEFGKNKLALVKLAKLFGHFSDLESLTAE"
     gene            complement(83961..84416)
                     /gene="argR"
                     /locus_tag="LLC22_000178"
     CDS             complement(83961..84416)
                     /gene="argR"
                     /locus_tag="LLC22_000178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBK5433487.1"
                     /translation="MKKKQRQALIRQIITEQPIGTQEELLARLHEAGADVTQATISRD
                     IREMKLVKSQNENKIVRYTLFNQPSVSLNEERLRTAIRREVLRIQSVQFMVIVLTERN
                     GADVVTNWLDEVAYPEVVGTMAGVDTFIIICRSEEEAQRFAEKLEKMRE"
     gene            complement(84514..85131)
                     /locus_tag="LLC22_000179"
     CDS             complement(84514..85131)
                     /locus_tag="LLC22_000179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GyrI-like domain-containing protein"
                     /protein_id="HBK5433488.1"
                     /translation="MEKIEWRKDKSYSMKKSPQILEVPKKSFFSIRGIGDPNQEDFKR
                     RVACLYAVSYAIRMSPKKNWLIPDYQMYTVYPLEGQWGLQEKYLHEPVMKKEHFSYQL
                     MIRQPDFVTEAIAQEAIQRSSKLPEDLKEQVVFKKMEEGLCAQILHVGPYAEEPATFE
                     KLEAFIAKEGYERASKEHKEIYISDPRKSAPEKMKTILRVKIEKG"
     gene            85352..86725
                     /locus_tag="LLC22_000180"
     CDS             85352..86725
                     /locus_tag="LLC22_000180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5433489.1"
                     /translation="MTKQKQLLLVPAVIATGMMSFAGVLIETAMNVTFPTLIRQFDLT
                     TAQVQWVTTIYLLMISIIVPLSTYLNRNFSLKKLFLASNLLFLAGIMIDFFSPTFMVL
                     LFGRLLQGAATGIALPLMFHIILTFAPLNRRGAMMGVGTLTTAIAPAIGPTYGGIMTS
                     HFTWNHIFLFLVPVLILSLIIGWFAIPEMAVQKSGYLDWISVLGICLLFSGSLTFLST
                     LGTVSSWIALIIGGIGWFLFYYRSKKVEHPLIRLSILSNKTFRLFLIGFLVYQFLLLG
                     VSFVLPNFLQIVQGSSPFVAGLAMLPGAAVGALLSPFSGKMLDQYGPKKPIFAGLILS
                     LIGWLALFLLIGHASVGVLIACHVFYMIGIGLSYSNMMTTGMNALNEELQGDGNAMFN
                     TLQQFSGAVATSLVAVIINYVQHHTSHNYEVSTTLGSKAALGVLLLLLLVSFARFAYY
                     LFFAKKA"
     gene            86800..87912
                     /locus_tag="LLC22_000181"
     CDS             86800..87912
                     /locus_tag="LLC22_000181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-binding oxidoreductase"
                     /protein_id="HBK5433490.1"
                     /translation="MEKIAIIGGGIIGMTLASYLDTSKFNVALFDEGTGQATKASAGI
                     ISPWLSKRRNKQWYRLAKDGAAFFPKLIKDFQLDQTIYAQSGTLLLRPEKDLAELAVL
                     AEKRKEEAPEIGNIEWLSPEQTSQALPLLKPAVSLRISGGGRLDGKAYLEHLGQRLAQ
                     KQMEQIQAKVTLHKKSDSWLIKGPFGEYTADRVILTPGPALKPLLQELGYAADIRPQK
                     GQLLAFQTSYKMSQDWPVAMLDGEADFIPFMDGKILLGATHENDQGWDLAPTSEAYKG
                     LTKSTEQFLTDPDQIKNWPYEFRVGTRAYTSDFSPFFGVLPDDPSLLAASGLGSSGLT
                     TGPYIGYLLANFLNTGHWPTEDYQKDISTYITKNPS"
     gene            complement(87984..89621)
                     /locus_tag="LLC22_000182"
     CDS             complement(87984..89621)
                     /locus_tag="LLC22_000182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate carboxykinase (ATP)"
                     /protein_id="HBK5433491.1"
                     /translation="MSTKESLELNEITSGNPLLSSIRSIVETTFYGNNVHEVFDRKTA
                     YQLAKGSPGTIITDLTISHAEELDLPADVRTLVFNDGSIVGRTASARRIFEDLDKEQS
                     KYEKILREAVYQSRKRQFYHTKVIVGLSEEFSVQSHLLIPEGFENNLYSYLLNFQPAN
                     SKILETYQKSVSFDEGDLYIFCDPEWTHETFPNGLILFDALHNTAVVLGLRYFGELKK
                     ATLTLAWALGNRNGFIACHGGMKQYASNDQTYTMAVFGLSGSGKSTITLAKHTEGHSV
                     SILHDDAFVISRKNGFATALEPSYFDKTQDYPSDDPAISSFLTCQNVGVTCTSKGEKV
                     LVTGDIRNGNGRTVKSRYATPDRVDHLSEKIDAVFWIMKDDSLPPIIKINDPVLAASF
                     GATLATKRSDAENITTKRQLDELVIEPFANPFRVYPLREDYQAFRELFLKQQTACYVL
                     NTGYFDDKKIKPETTLSIVERIVQQTAEFKSFGPFEDIHYLPIPDFPVSFEDTSYKNL
                     VKQRLDIRLRFIEAQIGKDLLPDEAKESLENLIQKLN"
     gene            complement(89789..90397)
                     /locus_tag="LLC22_000183"
     CDS             complement(89789..90397)
                     /locus_tag="LLC22_000183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5433492.1"
                     /translation="MNSFKKIVLGTTFAAGATAMFVGTTNAHADEVYTVKSGDSLSKI
                     SQKFAGDNSMIDAIAEKNSIANINRIYVGEQLTIPTSNDSSATTENKTTENTASTTET
                     ATQEHTYVAPVETVEVAPAAPAAATAPTSSSAKEWIAQKESGGSYTATNGRYIGRYQL
                     DASYLNGDYSAANQERVAEQYVTSRYGSWDAAKTFWLANGWY"
     gene            complement(90782..91933)
                     /gene="queG"
                     /locus_tag="LLC22_000184"
     CDS             complement(90782..91933)
                     /gene="queG"
                     /locus_tag="LLC22_000184"
                     /EC_number="1.17.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA epoxyqueuosine(34) reductase QueG"
                     /protein_id="HBK5433493.1"
                     /translation="MTLKEEIIQESKRLGIDKIGFTTAEPFDSLKESLEEQKAAGHTS
                     GFEHPNIDERLYPEMTFDQPKSIISIALAYPTRIHEEVPRDEKRGQFARASWGIDYHD
                     ILRDRLNRLIEFIQTRAEKWQKEEEWRLAPQVDTGELIDVAVAQRAGLGFIGRNGLLI
                     TEEFGSFVYLGEIVTNIVFEPDKPGEFGCGDCMRCVTACPTKALLGDGRMNAQRCLSY
                     QTQTKGMMPEEYRKKMRNVIYGCDICQLVCPYNQGKDFHFHEEMEPKVDEIYPKLKPM
                     LSMSNKDFKQQFGHLAGSWRGKKPLQRNALIALANLGDRTALPEISECLTDVRPVIRG
                     TAAWAIGRLGTKEPEKWLDVLDEILAKETEEVVINELEHAQKLLRRKLK"
     gene            complement(91952..92704)
                     /locus_tag="LLC22_000185"
     CDS             complement(91952..92704)
                     /locus_tag="LLC22_000185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433494.1"
                     /translation="MNFTRKDKYTIKEEVFRLISQQENTDKDQDLQFLEAELAKLFIA
                     NQNETTEPDEELYIGKWLFDEFQPLDENTGIGYFVFLSPVGFTPGVLVKQNDEITVKA
                     WPALFSVIKAEGVIKKIQSAYYKSQFIANSKLMNMFYNRLVEIARPGKIPQTFTYTQQ
                     KNLYEEVLYSRDLSEFSPWEEVRLHELLSTKPVSLNFFNALDNKRKLISTNYWEVFAA
                     RKKWMEEKKNADQQIQFVQLKKEKLYYGLYSR"
     gene            complement(92845..93794)
                     /locus_tag="LLC22_000186"
                     /pseudo
     CDS             complement(92845..93794)
                     /locus_tag="LLC22_000186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286843.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
     gene            complement(93795..94634)
                     /locus_tag="LLC22_000187"
     CDS             complement(93795..94634)
                     /locus_tag="LLC22_000187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBK5433495.1"
                     /translation="MIQSFIDGLMNYQFLQYALVTSMLVGLASGVIGSFIILRGMSLM
                     GDAISHAVLPGVAISYMFGFSYIFGATAFGMLTAAVIGFVTQRSRLKNDTAIGIVFSS
                     FFALGIILISYAQSATDLYHILFGNVLAVRESDLLLTALVSGIVLIFVFFFYKELKIT
                     SFDPTMAKAYGLNTSLIHYLLMFFLTLVAVVSLQTVGTILVIAMLITPAATAYLLTNH
                     LLKMIITAAGIGMLSAVVGVFFSYSYNWPSGATIVLACTAFFILAFLFSPTKGILFQK
                     GSR"
     gene            complement(94631..95377)
                     /locus_tag="LLC22_000188"
     CDS             complement(94631..95377)
                     /locus_tag="LLC22_000188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBK5433496.1"
                     /translation="MERTAIVIQDLSAAYQGKTVLKTINLTINPQKITGIIGPNGAGK
                     STFMKSLLELIPATTGKVTFSGQSVNSVRKKIAYVEQRSELDLSFPIDVLGVVLLGTY
                     PSLRIGQRPGKKEKERARQALKKVGMEEYAKRQISELSGGQLQRVFIARALAQGAEWI
                     FLDEPFVGIDALSERKIFDILQELKNSGKTILIVHHDLHKVEEYFDEVILLNKQLIAS
                     GPVQEVFTSKNLQLAYGEIIRHLVKGGEKK"
     gene            95615..96985
                     /locus_tag="LLC22_000189"
     CDS             95615..96985
                     /locus_tag="LLC22_000189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5433497.1"
                     /translation="MEEEKLTRSLSARHIQMIALGGTIGVGLFMGASSTIRWTGPSVM
                     GAYAIAGFFLYLIMRALGEMLYVDPSTGSFANYASEYIHPVAGYLTAWSNIFQYIVVG
                     ISEVIAVGSYMNYWWPDLPAIIPGIIVVLFLMLANLISVKAFGELEFWFSIIKVITII
                     LMIIAGLGVILFGFGNHGQAVGISNLWKNGGFFTGGVKGFFFALSIVVASYQGIELIG
                     MTAGEAENPKKTIIEAVQSTIGRILIFYIGAIFIIVSIYPWNQLSEIGSPFVQTFSKV
                     GITFAAGLINFVVITAALSGCNSGIFSASRMVYTLAINGKMSKKFLKLSRHGAPFYPV
                     VAISGGILIGLILNYLLPMFINQSENIFVFVYSSSILPGMVPWVVILISEIRFKKKHA
                     DKMHDHPFKMPLSPYTNYVTLAFLAIVLIFMFINPETRISLIIGLVFLLYMTIHYFVR
                     EKRTGK"
     gene            complement(97040..97936)
                     /locus_tag="LLC22_000190"
     CDS             complement(97040..97936)
                     /locus_tag="LLC22_000190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5433498.1"
                     /translation="MYDENEWGENVRMTRRRQQKQAARKRMIMIGAAVAVFLIIAGGV
                     AGLYFHGKNSSEAKSTTITETTTKKTETKQTSESSTKTKETQTSEEKTANGLPEQLQA
                     IVNDYSKKIEEKTPALIEEYQTEIQGNQEGIAGLSAVANQKARELQAISDEGIRKLRA
                     AYQAAENKDGVDLDTLINQLSANYTNHVAKISDIYLQTSASLQAESTSTQDTTSSDSE
                     TAESVEASEMQARTTQDTTDSSETNTNSATSQAATTVVLEGEGPNQIAERTGVPVETI
                     LSLNGMSMENYFLTPGETLKLN"
     gene            complement(98050..98220)
                     /locus_tag="LLC22_000191"
     CDS             complement(98050..98220)
                     /locus_tag="LLC22_000191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433499.1"
                     /translation="MTNDWLIQQLDELSEKSEYQDRALLYEIKKLMAEIDERTMQLQG
                     EIDGQSWNHLNW"
     gene            complement(98217..98894)
                     /locus_tag="LLC22_000192"
     CDS             complement(98217..98894)
                     /locus_tag="LLC22_000192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBK5433500.1"
                     /translation="MRTLIIISHPTIEESLNQQFFKEASAGLPATWHHLESSYPDGKI
                     DIETELQLLAQHDRIIFQFPFYWYSSPAHLKIWQDNVLERAAHVLKGKELGIVLTTGV
                     AEKEYQAGGKEEYTISEFLRPYQRIANKFHMTYLPPFVLAQFMYLSQEKRWEKLIAYQ
                     QYLSLEGKPSLTQRIDWFIQRVQENQKMQEEESEKQAYIVEALTEAKEQIEDLTFTLQ
                     EMKGTSL"
     gene            complement(98985..99890)
                     /locus_tag="LLC22_000193"
     CDS             complement(98985..99890)
                     /locus_tag="LLC22_000193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348792.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK5433501.1"
                     /translation="MEQSIFLKKEHQQVEKELYFDFCGFSKTMPFHSFGPAIRNDYIL
                     HVVMEGKGSYHVKNQQFQLKKGDLFLIRPGDSTFYLSDGEDPWMYCWLSFGGSAAEEI
                     IRQSLFREDQYTMVSSDIQKYIDIILECMKDTEETLENELQLTALTYRFLSVLLKDGG
                     KVSGGVQKVHSSLAVETVKYIEAHYAEKLSVEEIAQHLAVNRSHLSRVFKNHMGTSIK
                     EYLIGVRINRGAFLLSLTDESVESIAYQVGFNSLVVFSRMFKKSTGETATNYRKRMKN
                     KNFKNIALDTLKKQLEKQTTVSWTT"
     gene            100065..101519
                     /locus_tag="LLC22_000194"
     CDS             100065..101519
                     /locus_tag="LLC22_000194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5433502.1"
                     /translation="MKSKMIQRVSYALGAFGHDTFYVTLSTYFMVFVTSQMFAGTDKA
                     TNAKMIATVTSLVVGIRLVEIIFDPLIGGIIDNTRTKYGKFKPWLVIGGVVSSVLLVA
                     IFTNFFGLATHNTTLFIILFAIVFILLDSFYSFKDIAFWSMIPALSTETKEREKFATF
                     ARFGSSLGANGTTLVVVPIVTFFTYLVTHKHIEGASGWFWFGVIAAVISGGTAIITAL
                     GTKEVDTAIRQQNEKAGIKDVFKAVAQNDQLMWLALAYIAYAIANAATTAVLFYFFKY
                     VLGQPTEFWIVGLVAALLGLVAVPLFPMLTRVISRRYVYLGGIAMMISSYFFFTIAGS
                     SLPIVIIGLVLFYFPQQLIFLSALMTITDSVEYGQWKNGIRNEAVTLSIRPLLDKIAG
                     ALSNGIVGFVAIASGMTGNATAADITAHGVTTFKAYAFYAPAALMIFSAIIFAWKITL
                     TEKKHAQIVEKLENKLAPADTMEDELHDAVDPSH"
     gene            101535..102566
                     /locus_tag="LLC22_000195"
     CDS             101535..102566
                     /locus_tag="LLC22_000195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBK5433503.1"
                     /translation="MKITEKDFGQGYHLITLENKNKLALSISDLGARIVSLKSNDREL
                     VLGFDTAEEYIEKDPYIGASIGRTAGRIENGHFSLNGKTYQLATDPKTGHNLHGGAPG
                     FELKKWSYVILNGENEASVIFTTTSPDGEHGFPGTMDVEIRYTLTKDNIWRVTSRGTS
                     DQDTLFNPTNHVYFNLTGDASQSIDQHELWLNSEAYAPLRTDSIPIGVKENAAGSAFD
                     FQIPKKLASVFASDLDQKNLVDGIDHPFFLKETGLGKEAARLTSPDKRIQVDIATDAS
                     SVVIFTANFGTETPEMRNRKLAHHGGITFETQTAPGAERFSAFGSIHLKAGSVFETVT
                     EFKIKTRKE"
     gene            102573..103760
                     /locus_tag="LLC22_000196"
     CDS             102573..103760
                     /locus_tag="LLC22_000196"
                     /EC_number="2.7.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactokinase"
                     /protein_id="HBK5433504.1"
                     /translation="MEIKRSLNTKFAETFGPKKTTQYFSPGRINLIGEHTDYNGGHVF
                     PASITYGTQGVAAPRDDNKILVYSTNFDDIGVISFTLDELEYDKKANWANYVKGMVLK
                     LKEAGHSIDHGFELLVEGTIPNGAGLSSSASLELLVGVVLEDLFDLKTDRLELVQTGK
                     KVENEFIGVNSGIMDQFAIGFGELDHAILLDTNTLKYEMVPVKLDGYAIVIMNTNKRR
                     ELADSKYNERRSECEEALARLQKTLPISSLGDLDEEEFESTIDQIGDDTLIRRARHAV
                     SENQRTLKAKAELEAGNLEAFGQLLNDSHHSLRYDYEVTGIELDTLVDAAQKQEGVLG
                     ARMTGAGFGGCAIALVKEENIPAFKNNVYDEYMKVVGYAPEFYVAHIGNGTTKIDPEA
                     VHV"
     gene            103916..105298
                     /locus_tag="LLC22_000197"
     CDS             103916..105298
                     /locus_tag="LLC22_000197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Y-family DNA polymerase"
                     /protein_id="HBK5433505.1"
                     /translation="MWANQNPVFVYEKEPSRDILCIDCKSFYASVECVEKDLDPLTTK
                     LVVMSYPSDSTETRGSGLILASSPAAKKAYGITNISRARDLPFPYPSDLYIVAPRMAY
                     YMEKNREINSIYKKYADEANHHVYSVDESFLDVTNSMALFGKTNAYDMAKLIHKDVFE
                     QTGIYTTIGIGDNPLLAKLALDNGSKDGKQMFAEWRYEDVPEKLWKISDITDFWGIGK
                     RTAKRLKQMGIHSVYDLAHADYYHLKSKLGVIGTQLYAHAWGINRSFLGQEYTPKSKS
                     IGNSQILDRDYTRREEIEIVIKEMADQVGTRLRRSAAKTQVVSLWVGYSLGYLDPNGK
                     TGFHQQMKIEATNASRDLADALLTIFHQHYHYQDIRRVGVNCSDLVYATGLQLNLFED
                     PEKQINEAKVDFVVDTIRKKYGFQSIIHAHSLLQGGRAIARSSLVGGHAGGMSGLEGG
                     KDETDSKKIH"
     gene            105270..105656
                     /locus_tag="LLC22_000198"
     CDS             105270..105656
                     /locus_tag="LLC22_000198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433506.1"
                     /translation="MRRTAKKFIDYNEYRDRPFGLKWGTAFAMEELVNGIKKNEEEAR
                     KQPLPKQQMTLQEIDSILTEAFLSRKAVIIQLNLKDEFGRLLDEVEGHFIGEAYEDYF
                     MIDHQPILWEDVRYIELKETKKWFVT"
     gene            complement(105856..106524)
                     /locus_tag="LLC22_000199"
     CDS             complement(105856..106524)
                     /locus_tag="LLC22_000199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF421 domain-containing protein"
                     /protein_id="HBK5433507.1"
                     /translation="MIFSITMKLVFGLIGLLLVVRLLGKKSMSEITPFDLVYTLVLGG
                     ILEESTYDDNVHVGHVLFAIALWAVMIYGIERIVQKNEKVNRWVKGEPSVLIKDGVIN
                     MTELTNNHIEMEQLRAILRQQECFFLENAKHVILENAGQMSVLKKSDEDKALSILLVD
                     EGQIQHKVLQSNQLTEAWLMENLKKEGYADVKQLIYVEWSEEKGLYILNKEDVMHESY
                     RIDG"
BASE COUNT        30578 a        22268 c        18798 g        35105 t
ORIGIN      
        1 ctaatacagg tagtcctctt ttttgttatt ttgatattct aaatcatttt ttattggatt
       61 attcccttgt tcgatataga cccaaattga tctatcaata attatcaaac tgagtcatat
      121 agagacaaaa atttcaaaaa tgacctgtta aatggtcatc gaatatcatt taaaatcaat
      181 acgacggagt cagacacgga gtcaaaacaa gcccgctgag agtaaaaaat atatacagtc
      241 ccataggtaa agtgccacag gactgtatat ttttttattt gagattacct gaaatgattc
      301 catttacttt ttatctcatt ttttcctact agttagtatc aaatactctc ctattttctc
      361 aataaactat tttgggttac atggtatctg aaacagctaa aaccttgtca ttacagcaaa
      421 aaatcacttt atctccgttt catttcagat acatttcact taagcggatt ccaaaaaaac
      481 aaaagaaaaa ggaaccccta gttagcctat gctttttatt ggttcctctc aaaacacggt
      541 catataacaa cggggtgggg taaatgaatg aaaaaggtgg aggaaacatt attcaatagc
      601 tgtcttaaat acttcgttat aaaatgtgaa caaataaaag acatctatcc ctattttcta
      661 cacttccact ttactaccat ctttgaatcg tacaattttc ttaactcttc tcgtttacct
      721 caattcattt tcaagtggaa tcagctcatc atctaacatt ttacgccatg ctcgcttcat
      781 ttcttgtggg tatttaaatg gcttcgcttc tggatggttg gctttatatc cttcgtaatc
      841 cttactgttg ataattgctt tcatattagg aattggatct tcacctggca tatattgcag
      901 attagaagca tgtaattctt tctcagaaac aaaccactca ttggaaaaga catgaatcaa
      961 atcatcactc gcttgtgtaa aatagcgacg tttaatgaca aagatatctt cattactatc
     1021 taaagtcccc acatcaaacg catttaaaat ttgtcggtaa acttctttga ctccttctgt
     1081 tttattcaat ttagccaaag ctttttcaat ttcttctcgt gcatctgaac tattcgccgc
     1141 ataagttcct agtaattgat caatataagt agaatcaata tcatacaact tcgtggtatt
     1201 ttcactataa aattcgatcg tggaaaaatc ttctccctct ttttctggtt cttcctctat
     1261 taatgaaccc ttcacggtct cgtacacgcc aatttgttct tccaaaagtt gaatttgatt
     1321 gttcaaggtt gaagatttca ccatgtcatc attgtaatcg tcataagtca ctaacgattc
     1381 ataagcacga ttcaattctt ggaatgcttt gacgtactcg atacggattt caagtggcgt
     1441 atgttcatca atggattcca tggatgaaac ctcttttaac ttaccatatg cttgcttgaa
     1501 tctttttttg gattcctgat aacttggata aatcaaaccc gattcttctt ttgcttctga
     1561 atacagtttt gtcgcatcct cgacattctt ctccattgtg gctggctttc ggaaagtaac
     1621 aattagtcct tttgtttttt ctggatacgt acggttcgta cgtgaaaaag cttggatcaa
     1681 tcctgcatac tctagattac gatccacaaa tagggtttga atcgtaggtg cgtcaaaacc
     1741 tgtcaataga cgatccacta cgatcactaa atcaatttgt ttcccaaatt gtttgaattc
     1801 cgctcttttt cgtgccaaac gattattgat gtctccgtta taacgctcaa tgtctgctaa
     1861 tgaccaggaa gtattataat actgattata ttcctcaata attttttgca tttcttcttg
     1921 ttggacactt gaatctcggc tgttttcttc taatgaatag gtaatagcga ttcgtggaaa
     1981 atcaggatcc tccatcgttc ttccttcacg aatgggctga ttaggaaact cttttgttaa
     2041 ccagtcaggt tctttcgtca tttctttgat cgctcgataa tactttttgg ccatgtcaat
     2101 ggaactcgtg gttaagatcg cagacttcgt tggacggcca tttcgaaaat caaattttgt
     2161 ataggcattg tctggacgga acattttatg aatgactttt tggatatgtt catctgcttc
     2221 aaaaacagta gggtccaaat aactttcttt tttgacaggc tccatttgat caatcatacg
     2281 attgatctgt tccggtgaat actctgcata tgtttctact tcttttaatt tccgatagat
     2341 tttattctct aatgaagtcg gctccacggt gttttcatgc tctacttgaa atcctaaaac
     2401 cgagccatct tctaatgcat tcttgatggt ataggtatgc aagacctctc catactgatc
     2461 atgggtcgta cgtgccaatt gccctttggc ttgtttccga ttctcaggga aaatcggtgt
     2521 acctgtaaag ccaaaccaag tggatttcgg aaacattttt ttgatttctt ccatattttc
     2581 agcacttaac gctcgatgac actcatctac tacaaacacg atatgttgcc ccattaattt
     2641 ttggaagcga ttggttcctt ttttctcttc ttgttttttt gcatatttca acgccgcatc
     2701 tagcttttga cgggttgtaa taatcacaac atttgcattg gcatctgcca acagagtttc
     2761 acttaactct ttggcacttc ctgttcccac gatcaagcta ttcgctttgg cgttcccgga
     2821 agaaatccca gtattaaatt ccgaagcaaa tttcgtaaac tctgtggtgg tttgattatc
     2881 taaatctttg cggtccacta acatgatcgt ccgatcgatc cccgattttc gtgctaaaag
     2941 cttagtagat acaaaactag tcaacgtttt tcctgaacca gtcgcatgcc acacatatcc
     3001 tgattgatgt ttatttgcag caataaacaa ggcttgaatc gcatgtactt gataaggatg
     3061 taacaccatg aggattttat tgtcttgatc ttcactgaca atcgtataat ccgcaatcaa
     3121 gcgatgagca tccgggatat ttagcacttg tttgcaaaac tcatataagt tttctacctt
     3181 tttattatct ttcgttcgcc aactaaataa aaacttagga tgcaaatcct ttggtaaggc
     3241 atttgcaaaa taccgagtgg tttgttcatt ggaaaccaca aacaactgta aggtcgaaaa
     3301 gatattgttc cgaaacatac cttcttctgc atattttttg atttggttaa acgcctgata
     3361 aaaactatct tttgcggtta cttgtttcag ctcgatttgg acaatcggta atccattgat
     3421 cagtaaggtg acgtcaaaac gtcgatcccg tgcttctatg ttacttccac gttttgcaat
     3481 ttgatggacc acttcatagg tagagattcc tccaccaatg tcttgattag aataaagaat
     3541 gagcgagaca gaacccagtt gcggatcttc ccgttcaatc gtgatccgag ccattccatt
     3601 ttcacctttt aaccatttcg cagcatcaaa gggggttttc gttcgtagta acaattctgt
     3661 tttgatcgtt tcaaattctt tatcggtcaa aggaaaatca ttcagttctg cttgattatt
     3721 tgagatgatt ttttggcgta aattgaccca aagatcttct tctgatttta gatcgggacg
     3781 atacgtccac tgattatgcc cttcccccaa tacacggatc aactgttctt cgacttccgc
     3841 ttcctcacgg tgactaattt tcatttatct tccctcccta aacaaacatc ttttgtaaga
     3901 agcctttttt cgtttccttc agcaaatcta acttacgttg atgaagagcg atcgtgtcgt
     3961 cgagttgttt gaagaaagcg ccgatttttt gttgttcctc tttattccta gtaaaaggaa
     4021 acttgatatt agcgaaattc tcatagaata agtattctcg tacgcttcct tcagtgttgc
     4081 gcttgacctc tttgataaat gttggtgact tgataaactg aagtatgaac tcattatcta
     4141 agtcctcgct cattttcaca actacataaa gagagctaac aatgaccgtc ataccaagat
     4201 tgttaaatgc aattgatcct acgtttactc ttgctggatt ataggcgaat tcatttggtt
     4261 caacgaattt ataatttgtt ttttctaaat catccaacct actaccatca aactgttctg
     4321 tttgagaaat taaacctgct ttattactta ccgaataggc agggaagtct aaatctttcg
     4381 tgttcttttt tccagtcttc ttactaaact ctttgaactt acgctgttcc caatcttccg
     4441 taaatccagg aaaccgaatt tctggcactt ttgctccgtt tttagggaac attttttgta
     4501 agaatccttt tttcgtttcc tttaataaat ctagcttacg ttgttgaaga gcgatagtgt
     4561 cgtccagttg tttgaagaag ttcccaattt tcttttgttc ttctaatatt ggaaattgta
     4621 ctatccattt tttcacttct gacattggta cgagatttgt aattgctgaa cctggattag
     4681 ctcctgtgag ttttctttgc ataaaatctg cacgaataaa ttgaataaaa tattctgaat
     4741 ctgtgatttc tttatttatt ctaagtctaa tcaaagcctg attgaataca cccggtttta
     4801 tttgctttgg tactcttgaa attctcccaa ttgttccagc gccactcatg ataaaatcgc
     4861 ctggttctaa tttaaatttg attaattcat tatatttttt ttcagtaatt ttatatcttg
     4921 tttcgtaatt atcataaata gcattttgtt gttcatagac aacaaaattg ctattagata
     4981 caaagaattc tttctttaag gcactcccaa atggtcccct ccttactcca tcttttttat
     5041 caagtaagca ttcaaactta cgctgttccc aagcttccgt aaatcctggg aaacgaattt
     5101 ctggttgtat atcattactc atgtttgaac acctccagcg caccttgtaa ccacgcttca
     5161 ttttcaggtg ttgtttgcag ggaagagata gcttctaaaa gttctttttc tagcacttgc
     5221 tgttcttgtc gtatcttctt gatgtcattt ccgacatgaa ccatatcaat tggttcttct
     5281 tcttcaaacg tatctacata gcgtggaata tttaagttat agtcattttc tttgatttca
     5341 tcaaagtttg ccaaatgagc gtatttctcg acatcttttc tttcagcata ggtttcgagg
     5401 attttttgaa tgttttcttc cgataattta ttctgatttt ttcctttgac aaattctcga
     5461 ctagcgtcaa tgaataatac gtctcgagtt tggcggttct ttttcaatac aatcaccgtc
     5521 gttggaatcg atgtcccgaa gaacaagttc gcaggcatac cgatcacagc ataaatactg
     5581 ccgtcttcta gtaatttttg acgaatgacc ccttctgcag cgccacggaa taaaactccg
     5641 tgtggcaaga cgatggccat agtccctgtt tccttcaaat gatagaaacc atgaagaaga
     5701 aacgcaaaat ctgctttgga ttttggcgct aattttccat aacgattaaa ccgagaatcg
     5761 tctaagaagg tcgtatctgc tgaccaatta gccgaataag gtgggttcat tactactgca
     5821 tcaaatgtgt aaggttcatc tgttggccaa tccttattca acgtatcccc attgcggaga
     5881 ttcatttctt cggcatctac cccatgtaaa atcaagttca tttttgctag attgtatgtc
     5941 gttgtattta attcttgccc atgatattta acgttatctg ggtgagttaa gtagttacgc
     6001 acatttaaca tcaatgaacc tgaacccatg gttggatcaa aaacactaaa gaatcgtcgt
     6061 tctttttgat ccaacgtcac gatttgtgcc atcatatcag aaaccatatg aggcgtgtaa
     6121 aattctccgg ctttcttccc tgcttctgaa gcaaattgac tgatcagaaa ttcataagca
     6181 tccccgatca cgtccccatc gtgacctaaa acttccacgt cattcaattt cttaatgact
     6241 tcggtaatcg tcacatttcg ttgttgctca tctgttccta gtttttttga ttggagatcc
     6301 acatcatcaa ataacccatt aaattgattg taggtagatg ccaattgcac aaaggctttg
     6361 tttagatcat tcaattggaa cgttgcttgt tttgcttgat ccgctaagac gttgaaaaga
     6421 tactctggcg aaatcgcata ccccaaaata tcaacgattg ttgcaatcag atcttctttt
     6481 gattcttcat ctgaaagtaa ttcgcgatac aacatcgttt gtttgcttac cgtatcatat
     6541 tcctctaagg attcatctgc taaaagaacc acttgttcca acaaacggtc ggataaatat
     6601 ttatagaaaa tcagtcccaa taaataattt ttatattctg acgcatccat tttgctacgg
     6661 agattatctg ccgcactaaa taatttttga tttaattctg cacccaaaaa gatacactcc
     6721 tatctcttat ttaaagttgc tatataccct cttattttag catactccct tttagaaaaa
     6781 gcaaaaaaaa aagaaagaaa cttattcttg ctaataaact acgcgaaagg agtctaacgt
     6841 tgtttgatat aacttagact gatcgttaac ttatttttta tatttctaca tagttatctt
     6901 tagaaccatt tcagatacat atgaaacaat tacatatgat tttttcataa aaaaacagta
     6961 ctgtctagta gtataaaata tacaaatttc ttaaaaattt tttcactaaa atcactacct
     7021 gaaacagtct aaaacactta tatatcaacg tttaatgaaa ctatctccgt ttcatttcag
     7081 atacaaataa atatagtcgg gctccaaatc cgaaaaaaaa tacccccagt agcttatcct
     7141 aagctactgg agatgtataa gtacggtcat ataacaacgg ggtagggtaa ataaatgaaa
     7201 aagatggaag aatcattatt caataacttt tttaaatact tcgttgtaat cagttacctg
     7261 tccgttctta aataccacag aataatcttt tttcccattt tcaagtaacc gaagtggaat
     7321 atctttacca actttctctg tcactgcatt actgatacct gttagattag ctaataaatc
     7381 tgataaagat tgagcatctg tagaaatctc tgtatcagta tttatcgtga ttcctttatc
     7441 ttcatttaca agtttccaag taggtggtat agctgtgtat gtttctacaa atgaattaag
     7501 tttttcatta agtgacttct cttttatatt tccatctaaa aactctgtat atatggcttg
     7561 agctatacta aaacaaagct ggccttgttc taataatttt acatcattag ttagtaaagc
     7621 tgtgttcacg ttatcaatcg cttcaagaag agtatctttg gtgtccctaa cagctttagg
     7681 tgtgccttct ggaatttccc tacttgatac ctcgtccatt ttatcttcca taaacccctt
     7741 aaaatcatat ctttctccca aatccataga agtttttgag aaagctttca tttctgagtc
     7801 tatttcttca ataatattta acatgtctga tacatattgt ttaggctgat tcgtttttaa
     7861 tctatatgtg gtaaatatct caattcctcc aattatcaat aaaattgcca aacaaatcca
     7921 taataatttt ttctttttca tttttcctcc tatacactgc tgttataaca gtgactaatg
     7981 taaagatttt cccagcaatc atcagactat tatttacagg gaatcaaaaa aactccttag
     8041 taagcttaca cctttaggag ttcctgtttg aacggtatgc ataatacatt taaatcaatt
     8101 taacattaac acctcagtat atggtatctc tacatataca cggtcttttt ttggatagta
     8161 ctcgacattt atattgatag cacttccatt gtctaacgta gctttagccc ggtacgtgtt
     8221 atcaccatta tcatgagtga tcgtcacatc atcacatgtc cgatttaagt tatactgttc
     8281 ttgtaaaatc tgagttacca atggtacaga tgacttctct agtccagatg aacccgtcat
     8341 tcttgaaaaa attataccta taatagccaa tacaacgata cctataatga caaacttctt
     8401 attcatattt actttattca actttttatc tcctatctcc aaaatgattt tctctcatca
     8461 gtaactcatt gacatcccca atagtacacc aaagatggct ccagctaccc ctgctatcat
     8521 caaaatcgta cccatttgtt catctttctc tcgatataag taacccataa taacagcaac
     8581 agcaccaaat accacaggaa taaatgctaa tgatactacc atagaaatcc aaccaataat
     8641 caaatacagc ttccctgtct cttgtccatg tacgatttgt tccttcattt cattaattgt
     8701 ctgctcagta cttttcttta ctgtgtctgt tccggttgtc tcatctgttt cttgtaatgc
     8761 tccgcaaaac tggcaatact tactttcatt tgttatttct ttaccacatt ttctacaata
     8821 catgtcttct cctcctaaaa tcattcaatt gcttattagc taactgttta ctttattaaa
     8881 tacatcagaa aacagctcat ttattggtac acttaatatc tcagaaagca ttttcatttg
     8941 atagggttta ggaatcgttc tccctgtttg ccacgaactt acacattgct gtgtaacatt
     9001 catttttttg gctaactcag tttgggaaag tcctttttct tttctgtatc ggctgagatt
     9061 acttactttt ttcatgattc tcccctcctg ttttattata tacaacaata tgatgtattt
     9121 caactcataa aatatataaa tacttcaaat gtcattacaa atacaacaac ttgttgtact
     9181 ctactgagaa ggggggtgta ttaatgaaac agaagcaata tgcaaaggtc attagagaaa
     9241 agcgaaaagc actcgggtgg acacaaaaag aattagctaa aaaaatcttc tctacacaac
     9301 aggcagtagc aagatgggaa aattctgtaa cagaacctaa cctcgatagc ttaacagctc
     9361 tttctagagc cctaggaacc cctgtaagcc attttctaga caatgttgac atagattatg
     9421 aggaagagtt tttggctctc tatcgctctc ttagtactga agatgcaatt cgaacaattg
     9481 actatatgaa gctattaaaa aggcaagaaa atgaacgcaa tcagctattg aaagattgaa
     9541 aaataaataa cccaccgaac tttaacggtg ggtgtattga gatgaaataa gattaagagc
     9601 tatggataac ctgtctagtt taatataatt gggtctcttc tattccttac tctccgtcca
     9661 tcatctcttg ttacacttgt aaattgataa ataggaacta attcaactcc tgataatatc
     9721 aattctttta ttacttcatc tatccctgcc cctttcgcta gatatactaa aaaactactg
     9781 cttgctttca cattgtatag tttcttaata tccttagaag ctcgttcaag agtgaatcct
     9841 tgtttaacaa agtagcctct gttttctatt aaagcatttt tcacgctgtt atccctgaca
     9901 tttcgtaggc gttcacaaac agtgttaata agttcttttt ctgtcattag atatgtccct
     9961 tgccacgata agccctgtaa aacttcatgt gcttcatcta aaatcaattg tttttccttg
    10021 ctaagttctg atcgggaatt ttgaggaaat actcttttag cctctttttc gttaaaacat
    10081 atcttaaccc attcataaga aaaatattga tatgtaaaat gaaatttttc cagaagtgga
    10141 aggatatctt cattcaattt ttgaatcaca gaagttgcat taaaaacgtc taatcgatag
    10201 acattgcttc tcttatgttt aaagtttcct aacgctttct cttcctttaa cctatttagg
    10261 tattcgagca tcttcaaagg aacatcttca tcatctaatt tttttatcaa tcctataaaa
    10321 gtcataagtg atagtaactt attacattta tctatgtcat aagttttacc atagtaagaa
    10381 ctcatttttt tagctaattg ttcccccgac aaaatacaag tcacactttc cttactatca
    10441 tcaaaaaaat taacatcaga aagcaagaca tcatagacac gtcgcatttc ctctagataa
    10501 ttccttattg tcctgaaaag tttgtctttc attgattcaa gagtgtcaaa aagtactttt
    10561 gattcctctt tcaattttcg aaaatgtgta ggatacaagt ctaggttctc taatagccaa
    10621 ttaaatgttt ctacccgact gtctttcttt aaaattagca tcacaactcc aataaaattt
    10681 tcactgatat cacaattact ggaatgacaa taaaaaatgg aatgcccagt tttactggta
    10741 aaaatactag cagagggatt atgatcgttg tgaaacagac atcttaagtt tttacttgac
    10801 ttaagtaatt tattcatatc aatggttaac aatctttcat aaatctcatt aaaagacatg
    10861 tcggaggaat caaacaggca gtctttaaac cactgtttca tttcttcttt gtcgtcattt
    10921 tttatcaact taacaaaatc ggtttcattg actagttcat actctctccc tgaatcactt
    10981 tgacaatttt tagaacatgt catggtaaaa tcaatcggaa gctcagtaat atctaacatg
    11041 ttgtcttcat taattattat cactgcatct gacttatatc ctccaaaaaa cattctattc
    11101 gaagcattta cattgtcatc acacccgggg atgttctttt tcaagtattc gtaaacagca
    11161 accattttac catagtcagt aattgcttct tttaatagaa agacaatctt gtatttttct
    11221 agattttcag agtaccgaat acttttttgt atcgcaaacg cagaattatg aactaaattg
    11281 atagataaaa ccttttctat gcttaagtat ctactatcat ctttactcaa atctactacc
    11341 ttccccttct catctttaac agtgttatcg acatccagaa taattactct ggtttccaca
    11401 aaactctcct tgtcattgcc tttattcttt gtcttgcttg gaataaatga ttgtgatgaa
    11461 tttagtatct ctacaaactc atctcttgta acttctctat agttatctaa acacctatct
    11521 cttacatcag ttttttcttt ttttgtaact ggcttctcta ataatttttc ttgatctaca
    11581 taaattggaa tattaatcat tgatgtttcc atttgtgttt cctccttata aaattctgtt
    11641 aaagactaaa acatacagat aataaaaaca aactctttat tactatatgt tttagtctta
    11701 tttgtttact caacctttat accgttccat gaaactatca atatcagatt ttttaaatct
    11761 aatgaccgta tcaattttta taacaggtaa cccgtattga gaaacatatt ttctaatcgt
    11821 tcctactgat acacctagat attcacttgc ctgctgatag tccatatact ctagagtgac
    11881 tccagaaata atgtcttcta gcataggctt tagcactgta attatctctt tcacttgttg
    11941 ttcaacttgt atagaaacaa tgctatcaat gatttgtaga gacatatttc cccctccttt
    12001 cgtgattgct tgaacaaatt ttctaagaat tatcttcgta ttttttgctc aaaataaaag
    12061 tattttgtta ttaaccgatt aatcaaacaa aaaatgatta ccagttcatc gacatacaca
    12121 taatacctcg ataaaaaagg ggtgtcaaca gctttgtaaa atttatttac aacacccctt
    12181 ttttgaggta tactaatttt aggaggtgtg gtcaatatga taaaacgtcc accaataaat
    12241 tatttagaac gaaaaaagat actcggaaca aaaataaaag ctataagaaa gagtaaaaaa
    12301 ttaacacaac cagcatttgg tcttatgatt aacaacggtc aattaattga caaaaaaact
    12361 atctacgaat gggagaaggg aacctattta ccaataccag agcgattatc ccgaattgct
    12421 gatttgggaa atatgagtat agaggagtta gtttgtggca atgtagaaga atatattttg
    12481 ggaattattc tttatagaga tagcattgta ctagatggta taacatttcc agataaaaac
    12541 ctgttccagc atcttcgtca acagttccca ccagtacact ctaatttaga tacatggctg
    12601 gatagatatt ccaaattaga accagagatg caagaattta ttgctaacaa gacttgtaat
    12661 aaagttaaaa atgaaaaaat tagtcttttc aatatcttaa aaatagaaga attattcatc
    12721 aatgctattg tagaagaatt tgacaataac attcttttcc tcactagcag tatagaagaa
    12781 ctactagaaa gaatggtaga tgaatggcta cctattcaat tgaaagacat gtcttatccc
    12841 gaagaagctg tgagagaaat tactgataat ataaacaagc tagaacaaac gatttcatca
    12901 attgggaaaa aatacactaa gaaaaaaatg aagggaggtg ataccatcta gtggtaagta
    12961 ctccttgtaa actaagagga gatgatttaa tggcaaaaat atcaaagtac aaaaagaaaa
    13021 acggtcaagt ggcgtggatg tataaaggac acattgccac cgatccacga actggtgaaa
    13081 aaataaatac tacgagaaga ggttttagta gcaaacaaga agctcaaaaa gattatgacg
    13141 agtacagaca tcaaatatta tacggtgtta aaaagaaagc acctgatatg acatttgaag
    13201 acctgtataa tgaatggata actcatcagc gtaccagtgt taaagcttca acaatcgcaa
    13261 tctcagtaag atacgcaaat aatcaaatac ttccagcatt tggtaagctt aaactatcga
    13321 atatctctgt cccatattgt caaaaagtgg tagatgaatg gcacagtaaa tatgaaagtt
    13381 acgattatat gagaaaacag actgcacaaa ttttacgcta cggggttgca atgcaatata
    13441 ttgacaataa tcctatggaa aaaacacttc ttccacgaaa aaaagagtat gagaaaaatc
    13501 gtaaatttta ctcaaaagag gagcttaata atttactgga tgcttttaaa gattttggta
    13561 acatgaaaca atacgccttc ttcagattat tggcatacac aggtatgaga aagagtgaag
    13621 tactcgcttt acagtggaaa gacatagaca cgtttaataa agaactacat gtcaataaaa
    13681 ctcttgctgt agatgaattt ggtaaagtta taattcaatc tccgaaaaca agagcttcta
    13741 gacgagttat ctctttagat actgagactc tttctatcct caacaactgg aaattacagc
    13801 aaaaagaaga gtatttaaaa cttggataca atactagctc taaagagcaa catgttttta
    13861 caacagttaa aaacactcta tacattccaa acactgttaa tgattggtta agatatattt
    13921 tgaaaaaata taacttgcct cgtattacac ctcatgggtt tagacataca catgctagtt
    13981 tattattaga agcaggagaa tctgtcaagg tagttcaaca acgattaggg catgaaaata
    14041 gtaaagtgac attagacatc tatgcacata ttacaaataa tgcacctaag aaaacaggtc
    14101 aagactttgc tgatatgatg gctcatcagt aaaagagctg gtcaaaatct ggtcatttct
    14161 agtatacagg caaaacaaaa aagctagaac ccttatatat caagggttct agctcctata
    14221 acaggtttac ccaacactgc cttccatctc ataactgatc aatcgattga gttcgactgc
    14281 atattccatt ggaagttctt tggtgaatgg ttcaacaaag cccatgacga tcatttcagt
    14341 tgcttcagat tcggtcaggc ctcggctcat cagatagtag agttgttctt ctgagatttt
    14401 tgagactttg gcttcgtgtt ctaaagagac ttggctgttg tggatctcat tgaatgggat
    14461 cgtatcggat ttcgaccatt cgtccatgat gatcgtgtca cattcgatat gagagatcga
    14521 acccgcactg tttttggcaa aggttacttg tcctcgatag tttacttctc cgccgtcttt
    14581 tgaaattgat ttagagacga tagagctaga tgtatttggt gcattgtgga tcatttttgc
    14641 acccgtatct tggatttggt ttgctcctgc aaaggcgatg gagagcatgg tgcctcgtgc
    14701 accttttcca tctaagtaaa cacttgggta tttcatcgtt gtttttgcac ctaggtttcc
    14761 gtcgatccat tcaacggttg cgccttcgta tgcttttgct cgtttggtta ctaagttgta
    14821 cacattgtct gaccagtttt ggatcgttgt gtaacggcaa tacgcatctt ttcttgtaaa
    14881 gatttctacg atggcggcat gcaggctgtt acttgaataa gtaggtgccg tacaaccttc
    14941 gacatagtgg atgcttgctc cttcgtcaac aatgatcagc gtacgttcga attgccccgt
    15001 gttttccgca ttgatccgga agtacgtttg taatggaaca tcgactttga cgccttttgg
    15061 cacgtaaata aaggtcccac ctgaccatac ggctgaattc agcgctgcta atttgttgtc
    15121 ggttggcggt acaagttttg aaaagtactc tttgaataat tcagggtatt ctttcaaagc
    15181 agagtcagtg tcagtaaaga cgattcctaa cttttcgaat tcatctttca tattatggta
    15241 cacgacttct gattcatatt gtgcggaagc accggctaga taagctcgtt cagcttctgg
    15301 tataccaatc ttttcaaatg tatctttgat tttttctggt acgtcttccc agtcacgagc
    15361 gggtttgtca cttggttttt ggtaatattt gatggcatcg aaatcgatgt ctgaaaggtc
    15421 ggggccccat gtttgcattg gcattttgtt aaatgtttct agagatttca gacggaattc
    15481 aagcatccat tctggttcgc ctttgattct tgacatctca cggatcactt cttctgtcaa
    15541 gccttctcct gtactgaaaa ccggttcgac atcatcgtga aacccgaatt tatattcttc
    15601 taattctggt acgcccatgt tctcactcct cttccttgtg gtaatgatgg aaagctgcgg
    15661 taccatcgtt ttccattgct tttcctagtg ctttccaggc aagtgtcgca catttgatcc
    15721 gagcgggaaa tttagctaca ccaccaagca tagcagcatc gcctaattgg tcgggatctt
    15781 tgacttcttt tccttggaca agctgtagaa agtctacagt taaatgttct gcttcttcta
    15841 ttgattttcc gatgacggcg tctgtcatca tcgaggcact tgccgtactg atggagcagc
    15901 cactgccgtc aaaggcgata tttttgatga ttccgtcttt tacatcgact tgcaattcga
    15961 tcacatctcc acatgtgggg ttgttcaatt cgatcttgct tgtcgagtca gtcaagcttc
    16021 cacgatgatg cggatgggaa gaatgatcca agatcacttg acggtataaa ttgtctaatt
    16081 tagatagtcc catgttggaa aaactccttt gttgccatga ttgcttcaac taaacggtcg
    16141 gcgtcttgcg ttgtgttgta gaaataaaag ctcgcgcgag cagtcgctga tacttcaagg
    16201 tacttcaata gcggttgcgc acaatgatga cctgctctga cggctacccc ttccatgtct
    16261 aaagctgtcg cgacatcatg gggatgtaac ccatccaaat tgaatgcaac gactcctgtc
    16321 cgaaaattcg ggtcttgtgg accataaaca gtcaatccat caattgcttg taattttggc
    16381 aacacataag cggctagttc ttcttcatat cgatggatat tgtccatacc gagtttttgc
    16441 aaataatcga ttgcatggcc taatgcgata gcgccggcga tatttggtgt ccctgcttcg
    16501 aatttccaag gtagttcttt ccatgtactg tcgtataatt cgacaaaatc gatcatttcg
    16561 ccaccaaatt caacaggttc catttcttct aaccattttc gtttaccata taaaacacca
    16621 atacctgttg gtccgcacat tttgtgtccg ctgaaagcaa agaaatcaca gtctagtgct
    16681 tggacatcaa tggccatgtg cggggcagat tgagcaccat ctactacgat gaccccgccg
    16741 ttttcatgga caagttcagc taattcttga acaggattga agacacctaa gacattggat
    16801 acatgagcaa tggagacgat tttggttttg tccgtaatct ttttcgctgc atcctccata
    16861 tccaggaagc cttcttctgt tagttcgata tatttcaaga cagcacctgt tcgttttgcc
    16921 aactgctgcc acgggataac attagaatga tgttccatgt aagagagcac tatctcgtct
    16981 cctgctttga tatagcggtc gccgaaggtt ctggctaccc aattcaagct tgtcgtcgta
    17041 ccacgagtaa acagcacttc tgctgtttct tttgcatgga tgaacgcccg tactttttct
    17101 cttgcttgtt cataatcatg ggtcgcgcgt tctgctaacg tatggacacc gcgatgaaca
    17161 ttggcgttat cgtgttcgta atagtacgct aatgcctgga gtacttgttt tggcttttgg
    17221 gtcgtcgctg cattatccag ataaactaaa ggttcatcat tgacgtcttg aaataagata
    17281 ggaaaatcat tgcgtagctt tttagcatcg atcatccatt caacttccct tcgattactt
    17341 cgactaattc tttccgaact tgttctacag ggattgctgt taagacagaa ccgaggaatc
    17401 ctcgaatcac taagcgctct gcttcttctt tatgcaatcc tctactcatc agatagtaca
    17461 tttcttctgg atcaactcgt cctacactgg cagcatgtcc agcagttact tcgttttcat
    17521 cgatcaaaag aataggattc gcatcaccac gtgctttatc agaaagcatc aagacacgac
    17581 tttcttgttg ggcatctgca ccttttgccc ctttcaagat gtggccgata ccattaaagg
    17641 tcaatgttcc tttttctcgg atcactccgt gttgcaaaat atgcccgatc gtatgagggg
    17701 ctttattggt tactcgtgta tcgattcctt ggatttgtct gcccgagctg attgccacga
    17761 ttttgacttc tgcgtgtgca ccttctcctg ctaaatctga gtcaaagtca gcgatcacat
    17821 gaccgtcatt catgacacca attgcccagt cgacagaagc atctcgtaaa atgtgcccac
    17881 ggcgattcat ataagaagta atattttctc ctaattgatc tacggctgaa tatttgattt
    17941 ttgaaccagc tttagcgatg acttccacga tgatattacc tgatgatttt gctacttgtt
    18001 ctttggttgt ctggaaacgt tccagataag aaaattcact atgttcatct gccacgatca
    18061 acacatgctt gaagaagtgc tcatcggatg cgccatcttg aatgaataag gactcgagtg
    18121 gttcatcgat cacgacattt ttaggcacat acaggaaaat accgctgttc ataaaagcta
    18181 catggagtgc agtcaattgg tcttcgttca tgtttactgc ttttttcata taatattctt
    18241 ggactagttc tggatattcg atcattgcag tgaacaagtc ggtaaaaatg actccttttt
    18301 ctgctaattc cacaggcagt tgttcaaaaa tcgtccatga accttgttgg acaagcacag
    18361 gattgtcttt cattgcatca aatgccggaa tcgtgcctgt ttcactgatg gtttgtgttt
    18421 ctttcacatc aaataacgac cagcgatgga atttcacccg atcgatatgc ggcaatggca
    18481 gttcatctgc tttcgctagt gcgtcttgac ggaaggttct catccaatca ggttcgcctt
    18541 tacttaaaga aaaatcattt accgcgtcaa gataatcgag ccagtttttt tctttcattc
    18601 ttgctccccc ttacgcttct tcttctttat agtcgattcc taattcttta ctgataccag
    18661 cgtagccttc tgcttccaga cgtttagcta ggtcagcatt ccctgtcatg actactcggc
    18721 cttccatcat gatgtgaacg acatcaggtg tgatatagtt caataatcgt tgatagtggg
    18781 tgatgatcaa tgcaccgaaa ttgtctccgc gcatttcatt tactccttta gcaacgactt
    18841 tcaaagcatc gatatccaga cctgaatcga tttcgtctaa aattgcaaat gtaggttcta
    18901 acatcaacaa ttgcaggatc tcattccgtt tcttttctcc gccagaaaaa ccttcgttca
    18961 gataacgttc agccatttct tctggcatat ttagtaaagc cattttttca tctaactttt
    19021 tcaaaaatgc cataacagaa attttgtcgt tttcatcacg tttcgcattg atcgctgcac
    19081 gcatgaattc cgcattcgtg atacctggta tctcacttgg atattgcata gctaaaaata
    19141 agccaagtcg cgcacgttca tctacttcca agtctaaaac atttttcccg tcaaacaaaa
    19201 tttcgccttc tgttacttca tagtttggat tgcccatgat agcggcagat aaggtagatt
    19261 ttcctgtgcc gttaggtccc atgatggcat ggatttctcc ggttttcatt gttaggttta
    19321 cgcctttaag gatttctttt tcctcgatcg acacatgtag attttttatt tctaagacag
    19381 acatgcatta tacccccaaa ttctctttcg ttctcactca ttttagacta attgagaatg
    19441 aagcgcaatg accttcctta ctaaaatcaa atatctttta tttattatta aacaattttg
    19501 atttctaaat tagaataggt ataaaaaaga tgagaaataa gccattacag acttatttct
    19561 catctttttt gttccatacc ttattttgca tcagccttta ctggtttaac agagccgccc
    19621 catttgtctg tgatccattc ttggacttct ttgcggtgaa gcacttcaat cagttttttg
    19681 attttgtcac tgtcttcatc acctttacga gtcgcaataa tattcacgta aggagagttg
    19741 tccttttcaa gcaatacggc atcttctaat ggattcaacc ctgcgccgta agcgaagttt
    19801 gcgttgattg caactaggtc accttcatca ttttggtacg tagaagctaa aagtgatggg
    19861 tcgatcgtat ggttgaactt caagttctta gggttttctt caatatcatc gaatgttgct
    19921 gtttccagat ctactccatc tttgactttg actaagccag catcttgtag aattgtgatg
    19981 atgcgtcccc agtctgattc agaatttgaa gtaatgattg ttgcaccatc ttttaattcg
    20041 gaaacatctt tgactttttt agagtacaag cccattggtt cgatgtggac agcaccggca
    20101 ttgacaaagt catatccttt ttctttgatt tctttgttca aataaggaat atgctggaag
    20161 taattggcat caatgtcgcc ttcttccaaa gattggttcg gtaatacata gtcatcgaat
    20221 ttgacgattt caagatcgat tccttcatct ttcaataatg gtttcacatg ttccaaaatc
    20281 tctgcgtgcg gtgtcggtga agcgccgact ttcaatgtcg tgtcgtctgc tttatttgct
    20341 gaatctttgc tgtcgctgtt gttaccgcat gctgctaatc ctacagtcag caaaagcgct
    20401 gctgcaaatc caaaaatttt ctttttcata tcctacatcc ccctatatcc tattatcttt
    20461 tgtctgtttt cttagttaag aaatcaccga ttccttgaac gataaatacg attagtaaaa
    20521 taattaaagt cgcaacgaat gtcactgtta gattaccacg ctggtagcct tcctgccaag
    20581 caagacctcc aagtccacct gcgccgatcg cgccggccat cgcagtaaat ccgatcatcg
    20641 agatcgttgt aactgttaat ccagaaatca atgcgggaat actttcaggt atcaagacct
    20701 tccagatgat ttcccagtaa cttgctccca ttgcatctgc tgcttccagt acaccagggc
    20761 tgacttcacg aaaagcaatc tctactagac gggcataaaa tggtgctgcg gataaaacaa
    20821 gagctggaat ggctgcttgc gcacctagca tagtgcctac gattgcttta gtaaatggaa
    20881 tgatcaaaac catcaggatc ataaatggcg ttgaccggaa aatattactg atgatcgata
    20941 cgattccata aatgattcga gcatacggtt tgtttttgcg tccaatagag taaaggatca
    21001 atcccaaaac taatccgatg atcgtcacta agaccattga gattaatgtc atatatagtg
    21061 tatcaaggat agcctgattc atcgtttccg ggttgatttg tttaaaatct agatatgttt
    21121 ctgaaaagct tttatccacg atggatcacc tcaattccta ctccttgttc tttgatgaac
    21181 acttctgctt gatctaattc tttggtttca ccagtcatca agacagtcaa tgaaccaaag
    21241 gaaccttctt tcacttgttt gatctttcca tacacaacgt tgacatcgat gttatagcgt
    21301 cgaatcgctt gggaaatgac tggctcgttg gcatttcttt cgctaaaggt caaagttgcc
    21361 aaacggccgc ttggattttc tttgatgagt tcagctaata gttctgtcga atcagcttct
    21421 ggttcgatgt cttgttgtac aaagcgtttg gttacttctt ttttcggttg tctgaagaca
    21481 gtcaatacgt ctccttcttc tacgactttc cccaactcca tcacagcgac tttgttgcag
    21541 attttgcgga tcacattcat ttcatgtgtg atcaagacga tggtcaaatt caatttctta
    21601 ttgatcgcta acaataagtc taatacttct tctgttgttt gcgggtccaa tgcgctagta
    21661 gcctcatcac aaagcaggat ctcaggatca tttgccaatg ctcgtgcgat accgacgcgt
    21721 tgtttctgtc cgccggaaag ttgtgaagga tatgcttgtc cgcgtccttc taacccgact
    21781 aaacgcaaca gttcttctgc ccgttcttta cgtttgctct ttggtacgcc agctaattcc
    21841 agcggcagct ggatattttc aagtacagtt cttgaccata acaggttgaa atgctggaag
    21901 atcataccga ttttctttcg gaatgtacgt aattctttgt tttttaattt tgtaatatct
    21961 tgatcgttta cgatcacttc gccgctcgtg ggaagctcaa gtccattcag gagacggact
    22021 aatgtacttt ttcctgcgcc agaatagccg acgattccat aaatatcccc tttttcaacg
    22081 tttagtgaaa cgtcattgac ggcttggatg tttccgtttt tcccattgaa tgtctttttg
    22141 acattcgtta gttggattaa tgacatgcca ttcacatctt tctcttatga tttttcaaac
    22201 aaaaaagcct tcgccctctt gccttaagca aaaggacgaa agcttgaact tccgtgttac
    22261 caccttgatt taccgttact tcgcaataac agcctcttcc agtacttgga cttagcttct
    22321 ttccgtatac tgtcgcgctg taacgggcac tcccgtagta agtttgctta cgctcgctta
    22381 ctctgctcta agaccatctt ccatctcatt ttcgttaccc attttcagca aacagggctc
    22441 tcttcaaacg tccgtgacat gtactcttct tttcaaagct ttctcgtttc atataggatt
    22501 gcttatgatt atagcaactg gaagaatcag tgtcaacttt tttcaagtga ttttctgatt
    22561 ttataattcg tcaaattctt ttggatcaac atctttgaaa cttaagatcc acgcattcat
    22621 ttcatctgaa tcattcaaga tattgatatc ttcaccgatt ttatcattaa cagaagaaac
    22681 tgtacccgtt agcgggctgg caaattcatt gaccgctttt tccgcttcaa cttcgatcag
    22741 aggttcatct ttttttagcg attgtcctgc ttttggcaga ttggcaaacg tgatgtctcc
    22801 aagttcttct tgcgcttcat ttgtcaaacc aacacagtat tcttttccat taaataagat
    22861 ccaaaggttg tcctttttct tcaaatgctt gcctgccatt ttatatcagt tctccttcat
    22921 aaattttttc attgaatcca attgcaacaa gctggtcctc tcgtaagatc agtggtcgct
    22981 tgatcagcat accatctgtc gataagactt ggctcgcttt tgaagccgta aactcgccta
    23041 cttgatcttt cagtccaagt tcccgatatt tcatcccgct tgtgttgaac aggcgacgga
    23101 ttggtacttg actcgtttct agccaagtct caatcgttga ggccttcggt acttctttga
    23161 tcatatcaac ggtttgataa ctaacgccat gctggtctaa ccacgctttg gcttttttgc
    23221 atgttgaaca tttcgggtac cagtaaaagg tgtacaattt tcttacctcc ttgaagatct
    23281 tgcaggtgct tcattttggt atctcatcga taatatcaac ccgataccga tcatgttccc
    23341 taaaatcgag gatcctccct gactaatgaa aggcaatggg atccctgtta aaggaagtaa
    23401 tccgatattt gctccaatat tctcaaagac atggaacagc agcatcatga tcaaaccgct
    23461 tgcgatatag gcgtaaaatt cattattcgt atcgaaacac acccgaatca tacgatagat
    23521 taaaataaaa tacaagaaaa tgacgaatgc accaccgata aagccgaagt tttcaccgat
    23581 aacggtaaaa atcatatcgg actcacgaac aggcacatag atattgctta cgttgaatcc
    23641 tttaccaaac aagccaccgg taccaattgc caaaagtcct tgggccggct gataactcat
    23701 tcctgacgta tcatggaaag ggtccagcca tgaatcaata cgtgcaaact gataagattt
    23761 gaatccaact ttataaagca agtctcttcc gccttcagtc gtaaccaaga agatcgttcc
    23821 tgctccaacg actactgcca agattactac aggtgcgatg atgcgccaag agattccaga
    23881 catcaggaaa atcccgccaa agatcgcaag aaagacaagc atcgttccaa agtcatcttg
    23941 ggccatgatc aatgctaaaa ccggtattgt cacgatcaag agcttcccaa tcagccaaaa
    24001 gtccgatttc atcgtccgtt cttttacttg cgtattatgt ttagttacga tcagtgccat
    24061 catcaagatg tacgcaatct tcatcaactc tgctggctgg aaagtaaacg caccgaatcg
    24121 aaaccagttt ttagaccctg ttgaagcagc taaattctga tcatagaatt tgagcaagag
    24181 tcccattacc actaacccca aaccataaag gtaaggagtc agtttccaga tccatttgga
    24241 attcaaatgc atgatgacaa cgattgctgc cgctccaact aaataccaga caacttgcat
    24301 ccctacgcct ttcaagactg ctggattgtt cggatcatgg ctaagtgcta catataatga
    24361 gagcagacca atcaaacata acagaaagac tggtaaaatc acgccataat caatacgatt
    24421 atcgttcgaa gcttttaatt ttttttccat gtttcatccc ttttcttaaa aaccatactg
    24481 ctgattatta tagcggtcca gttagataat ggaaagtctt tccatagaca tttgggaaaa
    24541 attaactttc cgtttgtgca gttgcttgag caaatgcagt acaaaagcct actgcttatc
    24601 tttagtgtat catagaactt tttttgatac atgcaattat ctaccagctg agattctcct
    24661 cgctgtgaga agtttctgtg ctttcattgt atcgaaggat ctcttcggca atctctagca
    24721 gctgatcaga aaccagattg gttcgttgga tgaaataaaa atatcgatgg aaattcaacg
    24781 gagtcattgg cacattttct ggaacagagc gcttagacaa aatcgagcga ccgattcctt
    24841 ccttcagcaa cgcaacaatt acatcgttac ttttcacgat catcttctta tcttggatat
    24901 tcatctcttc aaaataacgc tgcgtgtaat gaaaaacacc agagtttgct tctcttacaa
    24961 gccacaattt gctttttggg tccccagcga tgactagctg gtcttccatc aaagagtatc
    25021 tttgtacgcc ggaagtctct aatggctttt cgataaaacc aaaatcggat tcatgtttcg
    25081 ctacttgttc taatgattca tgagaattcg tgatttcgat ctcaaaatgc actttaggaa
    25141 accttttgat cagatgtttc atcaactgag gcaaaagata gacagcaaag gtgtgggaag
    25201 caacgatccg acatacttct tcttcatttt gttcattgag caatttttgc tgagtttctt
    25261 cccattcttc taacaaaacc agtgtccgtt catataataa gtcggcttgc ttagttggaa
    25321 gcatctcttt tcttccgtta cgttgaaaaa gatcgatatt caattcccgc tccaactgtt
    25381 tgatttgatt cgagactgct ggttgagata aaaacagtac ttctgctgct ctggaaaaat
    25441 ttcttgtttc atatactgct cgaaaagtcg ttaataactt aaacatggca ccacttccat
    25501 aactttttat gataattact ataaaaacta tttgatttaa atatacaaaa aaccatctat
    25561 aatagaaatg tacaacaaaa cagttgctga tccaactagt aacttagatg aagacaatca
    25621 gctgtctgct tgctcgtaat catacattcc tattcatttt acaatgtatt cgttcatctt
    25681 ggtactaaaa tctattaaat aaaaaggaga atattatata tgaagaactt tttgaaaatt
    25741 attccgatcc cgatctgcgg gttgatcctt gggttagctt cccttggaaa tctgtttaaa
    25801 gactatcacc atgttgcttt aggcaatcta actggcggta tctctatgat tcttatgata
    25861 ttcatttttg ttaaattgtt tatcttattc gaacacacga aacaaacgtt gcatgatcca
    25921 atcatcgcct ccgtttcacc aacttttacg atgtcactca tggttatttg tacttatttt
    25981 gtttcatatg aaagtattgc accaattgtc aaattcattt ggctgtgcgc tgttatcttc
    26041 caagtgatcc ttgtctttta tttcaattat caccatgtta tcaaagctga tctttcaatt
    26101 gaagcaattt atccaagctg gtttatcatt tacgttggat ttggggtcat cactgtaact
    26161 gccgggaact tcttcccact tattggaaaa attttctttt ggatttcatt gatctgctat
    26221 gcgttcttat tgccgatcat catcaaacgt gtctttttcg taagaaatat ggctcatccg
    26281 acacgtccgc tgattacgat cgttgcagca cctggttctc tttgcctaac aggttatctt
    26341 aaaaactttg ctgaacctaa tttttatctt gtcgtagcat tgttcgcttt atctcaagta
    26401 ttgtatttcg ttgtgctgtc tatgcttcca cgtttgttca agcttcgttt ttatccaagc
    26461 tatgcagcct ttacattccc gcttgttatc tctgcaacag ctatatttac tactgttcat
    26521 tacttcaaca gtttaggtat ctatagtagc gtattggatt tcttaaaagt tgcggaatgt
    26581 ctgtttgcaa gtgtagttgt cttctacgtt cttgctcatt acgtacgttt cttaattaaa
    26641 gaacatagca aacatggaaa atttgtttct aaaaaaatcg cttaataatc gattcaatag
    26701 gttgtgaaaa agctgttctg catcaagtaa taagaacggc caaacaaaaa cagctgttca
    26761 tgtttttgta ctggttgggc ttattaccgc agatgcaagc ttttgaacac cgtttaccaa
    26821 gaggtcgtaa aagaagtggt cagcttcaag aaataagaag gaatttacga aaattgcttc
    26881 tcaaattttt gtgaaatttc ggcttatttc cgtagaagct acttctggaa caccgtttat
    26941 tcgaaacaag aggtcgtaca agacttttgt cacgacctct tgttcttttg tcaaaatact
    27001 ggtttagtgc tactatgttc gagtatgctt ttagtattta ttgacgaaag gaaccgatca
    27061 aatgaaatca ttgtcacatc caataaaatc tgtaaaggat tcagcggtcc gcgaaatctt
    27121 acccggttta ctgctttctt ttgccatcgc tgccttcagc aggcttcttg ctatttatct
    27181 gccacagtta ggtggagcga ctattgctat tttattgggt attttattag gaaatacttt
    27241 ttttaaacag cctgttctag caatcggcac aaaatttgct gaaagcaaac tattagaatt
    27301 ctctgttttt ttactaggtg caactgtcac agctcaaacg attgctcaaa ttggtgtaaa
    27361 aggaattgtt tttgtgttac tgcaaatgtc agtcactatc atcggtgctt acttgattgg
    27421 taaaaaactg caattcagcg atacttcttc tttgatgatg gctggaggaa acgctgtttg
    27481 tggttcttct gctattgctt caatcgcccc ttccatccat gcgaaagagg aagaaaaagg
    27541 acagatcatc acactagtca atctactggg tactgtgatg atgttgactc tcccttttct
    27601 tggattacag ttgtttggtg gaaatctcat tgaaaaaagt gcacttttgg gtggtacact
    27661 ccaatctgtt ggtcaagtag tcgctggggc aagcttactt gacaattctg ttgtcgaatt
    27721 cgccatgcta tttaagattc tacgtattat gatgctcgtt gttgttgtct atctgtttga
    27781 aaaattcatg cacaagaaac aaccagctct gtttgaaacg ccaactgata cgcagaaaaa
    27841 acgaaaatta ccgcttcctt ggtatgtatt agggtttgtg atcttttgtt tggtcaacag
    27901 cttgttttct ttacctgtag ttattgacca atcggcacat tttatcagca gctggtttga
    27961 gatcactgct ttagcggcaa ttggtctgcg tttagacttt gcaaaattca tgaaagaagg
    28021 tacacgcttc ttatcttatg gattagctgt cgggcttctc caaacagtga tggctttact
    28081 atttatttgg ctgatcaaag tttagaatga acatgaaaaa acagttgtga ttctcgcatg
    28141 gaacaatgtc cgaatcacaa ctgtttttaa ttttgcagat atccttctaa caacaacaat
    28201 tggcgtttga tttcaacccc atctattgcg tttcccatat atcctgtcag ttttccattt
    28261 tgcccgatca ctcgatgaca aggaataacg attggcaatg gattggttcg atttgcctgc
    28321 ccaatcgctc gcacagcttt cggactatca acagcaacgg ctacttcttt atacgttcgg
    28381 atttctccat aaggaatggt cgacaaagct ttccagacat tttgctgaaa aggcgtacct
    28441 ctctttatag ataaaggaac atcaaattct tttctttttc ccgcaaaata ttcttcaaac
    28501 tgttcttgtg tgcgcgttaa aattcgctga ttcgctgatt cgctttctga aattggctga
    28561 aaagatacag cagtcaatcc ggattcatct gcatctaacc ataaaaagcc gataggtgtg
    28621 tgtattttca ttttgtttgc tcctagtcaa tagactggaa cttcctcctt tttctctatc
    28681 caaaactact tgccaactaa taaaaattgt tcttaaaagt ttgataaacc gaggaaacat
    28741 ggtaaactaa atacgttagt ttacaaaaag aatacctgtt cttttacgta aaatcaaatt
    28801 ttaaaggtgt tatttaaggt ttattaaatt ttgaatgtaa accatatata aacatacgat
    28861 tgaaaggata gaaacgatga aagtatcaat tgttgtccca tgttttaatg aagaaaaaac
    28921 tgttcctctt ttttttgatg aggttgaaaa attcaaaggt gcccatgagt tcgaatattt
    28981 gtttattgac gacggatcaa aagacggtac gttagcagca atcaagaagc tagcctcagc
    29041 ttatccttat gtccgctttg tctcattttc cagaaatttt gggaaagaag cggctctgta
    29101 cgctggattg caagcttcta caggagattt agtgaccgtg atggatgttg atctgcaaga
    29161 tccgcccgaa ctgcttcctg agatgatcaa ccggatcact acttctgata tcgattgtgt
    29221 cggcacccgg cgttcgactc gtgaaggcga gcctgcgata cgcagtttct ttgcgaaaaa
    29281 attctaccag ttgatcaata aaatcagcga tacagaaatg gtcgatggcg ctcgtgattt
    29341 ccgcttgatg actcgtcaaa tggtggatgc cgtcctagaa ttaacagaat acaaccgatt
    29401 ttcaaaagga ttatttagct gggtcggatt taaaacagaa tatatttctt atgaaaaccg
    29461 cgaacgtgtg gctggcgaaa catcttggtc cttctggaaa ttattcaact actcgattga
    29521 tggtatcgtg aacttctcgg atgcaccgtt aacgattgct tcatttatcg gcgctttgtc
    29581 ttgtgtcggt tctggtattg caattttgtt cattattttg cgggcattgt tgtttggtga
    29641 tcctacatca ggatggcctt ccatggtctc gatcttcctg ttcattggtg gaatccaatt
    29701 gttatgtctt ggaatcatcg ggaaatatat tgggaaaatc ttcttagaaa cgaaacagcg
    29761 tcctgtttat atcataagag aaacagaaaa agtgaagcca aatgaattga agcctcacca
    29821 ataatatacg tcaaatgaag taaacatttt tttaaatgaa aaaggactgt gacaaaagtc
    29881 ttgtcacagt ccttttttcc gaataaatgg tgttccagaa gtagcttctt cggaaataag
    29941 ccgaaatttc acaaaaattt gagaagcaat tttcgtaaat tccttcttat ttcttgaagc
    30001 tgaccacttc tatcacaacc tctttcatat cttattactt cttcattgct gcttttagtg
    30061 ctgctgctaa tgggctttct tctggttctt ctgcttgtgc atattttttc agcaagcgtc
    30121 gttcttcatg tttggtcatt ttcttcttct gctctttttt atcaagcaat ttttctgtcg
    30181 ttccatcgta tttacaacgg aaataagcac cgtttttacc ttcgatgatt tccattttcc
    30241 ggtgacattg cgggcatcga tgattagaga cttttggatc ttttcttctg cggtagttgc
    30301 aatctgaatt ggtgcagaca tagattttgc cgtcacgtgt gtttttctcg cgcagattgg
    30361 ccccacattc tgggcatttc ttttgggtaa tcgagaaatc ttgatattct tgtttgcttg
    30421 atttgatctc attcaccaag cgttttgttt ctttttcgat tccattcaag aaggttcctg
    30481 cttgtttctt tcctgcagca atagcttcaa ggtctttttc ccagctttct gtcaaatctg
    30541 gtgttactaa agagggattt accaatacta ataattgctt acctttagga gatacttgca
    30601 gtccttgagg ggtacgttcc atcagttcag atttgattag tttctcgata atctctgcac
    30661 gcgtagctgg ggttcccaga ctgtattttt ccatttgacc aagcaagctt gcttctgaca
    30721 atggtttagg cggtgcagat agttcttttt tgatggcgaa atcgggattg attctcattc
    30781 ctttttccca tttgactgtt tccgtctcag tttcagtttc gcctttccat cctgcttgga
    30841 cgacacgatt ttgccgaaaa atgaatcgtt ctttaccaaa ttcaaccgta acttttgttt
    30901 ggctgacttt atggggttga gcaaacagtc ctaaaaaacg agagacaatc atttgataga
    30961 tttttcgctc ttcattactt aatttttcat aacgtgctct gttttcagtt ggcaaaagtg
    31021 catggtgatc ggtcacttta ctgtcttgga atacttttgt ctgttggacg atggctccgt
    31081 ttttcaaata ctgcttgacc tcaggagcaa agtcgctgac tgcttgcaat cgttctttca
    31141 tcgtactttt catgtcattt gtcagatatt tgctgtctgt acgcggataa gtaacgatct
    31201 tatgggtctc atacaaactt tgtacaagac ttaatgtttt ctttgcagaa tagccatagc
    31261 gttgattggc ttctctttgg atctctgtta aatcataagg caatggcgca gattccgttt
    31321 ttaatttttc ttggacttct gtgacagttc ctttgcttgt actgatcaat tgaacaagtt
    31381 tttgtgcttc ttcttgtgtt tttaaagcaa attgattttt ttgaagcatt ttggcttgtt
    31441 cttttccagc ttgcaacgtg atcgtgaaat acgtttgtgg acggaactgc tcgattttct
    31501 tttcttggtc tctcactaat gctagtgtcg gtgtctgcac acggcctgct gataaattat
    31561 ccgcgtactt cacagttaag gctctggtca cattcaatcc taccagccag tccgcttttg
    31621 cccgggcaag agcagattca tacaatgcat catattcttt cgcaggtctt agttgcttga
    31681 atccagtttt gattgcttta tctgtttgag aagagatcca taaccgcttc actggtttat
    31741 tgaaatgcac atactctaag atccagcgag caacaagttc cccttctctt ccggcatctg
    31801 tcgcaatgac tgcttctgag acatcttttc gctgagccag ctgcttgatt gcttttaatt
    31861 gatgtcctgt tttaggaagt ggtttgattc ctagtttttt agggatcatt ggcaacgtgt
    31921 ccatttgcca gctctgccat tccttattca gatcttccgg cattttcaat cctaataaat
    31981 gaccaagggc ccaagtaacg atcaccttgg gtccttcata ataatttttg tgcttttgat
    32041 tagcaccaag caccttgctt aggtctttcg caacgcttgg tttttccgct agaattagtt
    32101 gtttcataaa attcctttct gctttctact gtgatgggct gatgattttt caacaacgca
    32161 agtcccttgt attgctgtaa atcatcgtca cactcttcac accagcgctc atctccgtca
    32221 ttccaaaagg cgctgagaaa gttacttttt gcattgatat attcataatt ttgatggatt
    32281 tcgttccatt gtttttcgta cgcttgtcgt gcttcttcga aagactcgaa tgtttcttct
    32341 tcttcaatat cttcttccca gtcttcaaaa aaccaccaag gctcattgtc cccgaacatg
    32401 gtaattactt gatacatact cgtgctcctt ctttcagctt ttctagactc atcttagtca
    32461 cttttcaaga aagttgcaag aattttctct tataaaaggg tcatttaatg aacatcttaa
    32521 aattgttaca aatgaatctg attgtttaag gcaaagtagc gataaagtta ttgatcatcc
    32581 aaaaatagct gtcttctgga tcgattgttg gttcttttgt aaagtatcct aaaaaacgta
    32641 aggaaagata accgtggatc atactacgaa gttccctgct tcgatgaact ttttcttctt
    32701 tcgttaattg aaaagcctca aatatctgca aaatgatctg attcgtttca tggattccat
    32761 ctaataaaac agcttcattg gtatgcggta cactgatcag taactcatac actgcttgat
    32821 ttgaaaaagc aaaggatcga taagtttctg catagatctg cagtgcttcc tgaccacttt
    32881 ttcccacaag agcccgtcgc agctggtcat taagttcctg cagaagtttc gctgttagcg
    32941 ctgttttgac atcacgaata tttttgaaat ggttatacag cgagggagcc ttgatatcca
    33001 agcgtttggc taaatgctga aaggttattt gctgaacatc catctcttct gctagttctc
    33061 gaaagcagtc gatgattttc tcttgagaca gatttctttt tttcatttcc atgtttcctc
    33121 tcataaaata aatccttcac tctttcagtt taccacgaaa aagaaagaga aaaaagagac
    33181 tttcattgat aaactacata ttgtagttta taataaagag ctgtagatga aaattttcag
    33241 aaagaaggag tctaattggc tgcaagaata aaggaaaaat tatttaggaa aagagaaact
    33301 tgggaacaaa acttgtttgt cttatggttt ggaacattta tggctggtat cggatttagt
    33361 ttagtcatgc cttttatgtc actttacata gatacgttag gtaattatag tacgtcacaa
    33421 ttgaactttt ggagcggatt gactttttca tctactttct tggtgactac gcttatctct
    33481 ccttggtggg gaaaattagc cgaccaaaaa ggaagaaaat tgatgctgtt gcgtgcttca
    33541 ttaggaatgg caatcgtcat ttctttgatg ggttgcgtga ctagtgtgta tcaattagtc
    33601 gcattgcgtc tgcttcaagg gattttttct ggttatatca gtaatgccac tgcccttgtc
    33661 gcaactggga cgccaaaaga aaaaagtggt caagttcttg gaaccttagc aactggttct
    33721 gttacaggaa cattacttgg accgcttctt ggcgggatct ctgcttcagc gtttggctat
    33781 cgccctacct ttttcattac agggatcatc ttatttttcg tcttcttgtt gagtctgttt
    33841 ttcgtccatg aaaaatttgt cccagtgaaa aaagaaaaca tggtttctgc caaacagatt
    33901 ttcaaagact tgaaatatcc acacgtcgtc atcggtatgt tcgtcacaac gatgatcatc
    33961 caagcatcca acaattccat tagtccaatc atcagtctgt acattcgcca attgctgcat
    34021 ggacatggga atgttacgtt gatcagcgga atcattgctt cgatacctgg gattgccact
    34081 ttgatagccg ctccaagatt tggtcgctta ggtgacaaga ttgggagtga aagaatactt
    34141 gcgattggtt tgggttttgc gattctggtt tatatcccaa tggcattcgt cacgaatgtt
    34201 tggcaattag ctgccttacg ttttttgatt ggtatctctg atgcttgtct gctccctgct
    34261 gtccaagcat tgatcacaaa atattcgcct catcaagctg ctggacggat cttcagttat
    34321 aaccaatctt tccaagcaac tggtaacgta gtagggccta tgatcggctc cagtgtttcc
    34381 agtgcatttg gttatcgtgg cgtctttctt tcgacttctc ttcttgtttt ggtcaacttc
    34441 ttgcttgtac gacacaatac acaagagatc catcagcaag aaactgcaga agaaaaagct
    34501 tcaggagtct ccatagcttc agggcactct ccttctcata gacaataagc gtaaatgaaa
    34561 aacactgctt gaacagttgt cacagactgt ccttgcagtg tttttgttta ggcctgtttt
    34621 ttcaagaact cagataagag gaataatccc ttttccaagg tttctttttt acaacagtaa
    34681 cctagtcggg catgcttcgg taaatcaaag gcacttcctg gtactaatag tactcctgtt
    34741 tcttctaata aattgataca aaatgtctgg tcatcttctt cgatggctaa tttaatgaaa
    34801 gaagtagaga cgtaattggg agcgacaagt tcaactttcg gttcattggc tacccattgt
    34861 tttaaaatca caaggttctc tgtaatgatc tttttgtttc gcgccaatat tttttcttta
    34921 ttcttcaatg catgtacagc aagatcatct gacaggactc cgccgcaaat catcgtgtag
    34981 tctcgatact ttcgaaaaac ttctgccaac tcaggtccag tagctgtcca gccaatacga
    35041 atacctggaa tggagtaggt tttggatagg gaattggttg ctataccttt ttcatagaca
    35101 tctacgatcg acaagaattc acctttatcc gttaaaggcg catatacttc atctatcaat
    35161 acatatgcat ctactgtacg agcaatttct gcgatttttt ctaaagtttt ccgatctagc
    35221 aatgtgcctg taggattgtt tgcactattc aaacagatga tttttgtttc aggtttgact
    35281 aaggcttcta gctgttctaa atcaaactgc caatcttctt cttccttcaa atgaacaaag
    35341 tcaacagcgg cacctaaaga tttggggatg tcatataatt gctgataagt aggaagcatc
    35401 gaaacaacat ggtctcctgc ttccactaac gcgtatagag ctaaaagatt agcaccagtc
    35461 gctccattcg tttgtaagat gttttccgga tcgacggttt gataaagaga agcgacttct
    35521 tgtttgaaaa catctgatcc ttcgatccag ccatagtcca atggttcgtt tttgcgtttt
    35581 tcgaaaaatt tacttacgct agtcccatct aagccaacga gttcgtctaa tgtcaatgct
    35641 tcgatcgagc tttgtgcaat atcatatacc gctttctttt cccatttatt tagccattct
    35701 tctacaccga aatttgcgat tttcatgttt ctttccccct tatatcttga tccagcctac
    35761 agcaagcaac ccgattgaaa gcagtgcggc cacacaaatc agcccaatca ttactttttc
    35821 ttttcccgta atttgatgtt tggtttcacg acaagcgatc cagtagaagc aaaaaccagg
    35881 aagataggca atactacata aaaggacata agaaaatcct gctaaaatga tgcccatcaa
    35941 ttcaaaaact acagcaatcc caccgatcac tacttgtttt ttgattcctt cttttaaaga
    36001 aaactggact tgatagatcc cgacaagtag ataacaaatc aaaattgccg ctgtacataa
    36061 agaataggca aattgatagg cataatcagt aactaagaaa gtcaataaga atagattagt
    36121 caagattgca gtaacaacta acgaataagt tggggcattt tttttattcg tttttcccca
    36181 acctttcggc aacagaccgt ctcgagccat caacatcgtt gtttctgctg ggagcatcgt
    36241 ccaagacaac caagaaccaa tgatcgaaat aatcaagccg atattgatca gcgctgctcc
    36301 ccaatttccc acgattcctt ttaaaatatt tgccatagca ggttgtgaaa tagttgctaa
    36361 ctcttcttga gataagacgc cgtatggcaa gatcgaagca aggatataga taaacaataa
    36421 acaaagcaga ccaatgatcg atgcttgctg ggcttctgaa cgtttcttcg cgcggttggc
    36481 taaaacactt gcgccttcga tccctacaaa gacccacatc ataaccatca aacaaccttt
    36541 aatctgcaac cagatcgttc cttgctgccc tgttccattc actagattat cagatacgtt
    36601 accccaaaaa tcagcagtga atatattcac tttaaatgcg ataaatacaa atattaaaaa
    36661 taggaataat ggcactaatt tacagatcgt cacgattgta ttgatgacgc tcgctccttc
    36721 aactccattg tttactaata aagtcagacc ccaaataaaa atacttgcaa ataaaataga
    36781 aggaacattt tgtccacctt tgaatatcgg gaaaaattct cccatggcgc tcatcagcat
    36841 cgttgcaaaa gcaacatttc ccagccacgc agacaaccag taaccccaac cactgatgaa
    36901 gccacctaat ttaccaaatg aagcttccgc gtaaccgaaa ataccaccat ctagatctgg
    36961 acgcttttct cctaaatgat tcagcgataa taccaaagct aaaataccaa tcccaacgat
    37021 tatccatgaa aggatcgctg gccctggagc tgcagaacta gccagatcac ttgtgatccc
    37081 aaacacaccg cttccgattg acgaactgac aaccagagca accagtcccc atttgctaat
    37141 acccgtcgat ttcttttcca tttccatcac cctcacttat aaaattgaac aaatcacttg
    37201 caaaagattc ccttctattt tgcaactgct cttgcttaac aaaaagcaac tttattcata
    37261 ttattggata ttatgaactt tttacacaag tatttcaagt ataaaatgaa taaaaattaa
    37321 ttttattgca aaaaaacagc tatgctatcc aaaagaaaag gtgtttcttt tgttagccat
    37381 agctgttttg attcatttaa tatcgcttaa acgtattgta aaacttttgt ttcttgatat
    37441 gcgtggtcga tcaaaccacc acccagacat tccattccat cataaaatac aactgcttgt
    37501 ccaggagtga ttgcacgtac aggttcgtcg aatacgactt ctgcacgatt atcatccaat
    37561 aagcgaactg tcacaggaac gtcttgctga cgataacgga atttcgctgt acacttgaat
    37621 tcttttggca ttggttcatt cgtcgtaaag tggatttcac ttgcatccaa gcttgtggca
    37681 tacaatgcag gatgatggaa cccttgcccc acatataatg tgtttgtcgc tagatctttt
    37741 cctacaacaa accagggttc ttgcgaatct cctccgccac cgatccctag tccttgacgt
    37801 tgaccaatcg tataatacat caagccagca tgttgtcctt tgacttcacc atcaagagtg
    37861 accatatttc ctttttttgc tggcagatag ttgctcaaaa attgtttgaa gttcttttca
    37921 ccaataaagc agattcccgt tgaatctttt ttcttagcag tcgcaaggcc tgcgcgttca
    37981 gcaattgccc gtacttctga tttttccatg ccgcctagag ggaacatcgt ttttgaaagc
    38041 tgttcttgtg ataattggct aaggaagtaa gtttgatctt tattattgtc tactccacga
    38101 agcatgtgga ccacgccgtt ttcatcgcga gtgacttgcg cataatgtcc agtagctaca
    38161 taatcggcgc caagatccat tgcataatcc aagaatgctt tgaatttgat ttctttgttg
    38221 cacatcacgt ctgggttagg tgtacgtcct gcgcggtatt cggctaggaa atattcaaat
    38281 acacgatccc aatattcttt ttcaaaattc acagagtaat aaggaatccc gatttgagca
    38341 gctactttcg ctacatcctt ataatcttcc gtggccgtgc atacaccgtt ttcgtccgtg
    38401 tcatcccaat ttttcatgaa tattccgatc acgtcgtatc cttgttcctt taacaaaagt
    38461 gctgttacag atgagtcgac accgccgctc atccctacga caacgcgtgt tttgctgttg
    38521 tctgtcatga tatcaccatc atttcaatta gattctgaaa catctacgag ttgaaggtcg
    38581 caacttttca gtattttaca ttatacgtca tatttctgaa aatttcatcc cttaattatc
    38641 aagtcgtaaa aatactgttc tactggacct attcagtaca caaacatgat agtcaaccaa
    38701 aaaatcactc atcttttgag cattcgatat aaaaaattgg catactcata aaaagggcca
    38761 gcctttcggc aataaggaat aattttataa attgtgaaaa actatttttc aaaattgctt
    38821 cttatcgctt aaagctgcac gtctcattta caaccttttc tttttagatg ttatgagttg
    38881 ctcagataag tgattttgtt tactctaaga aaaaagggag gcaaaagata catgaattac
    38941 tttatcagtg atatgcactt tttccatgaa cacttattag gaaaaaacga ctttgctccg
    39001 cggctctttg caaatgtgga tgaaatgaac caacagttga tcactagctg gaatgcagta
    39061 ataaaagaaa ccgaccatgt ttatcatcta ggcgaccttg ctatgcatcc gcaatatgaa
    39121 aaagcaaatg cagaaatttt ggaactggtc actcaactgc aaggaacaat ccacttgatc
    39181 aaagggaacc atgacagtcg cgcttttttc cgttatttag aaaaaaatga tcctaggctt
    39241 actgacggaa gtcccaaatt ttatttttat gatgtaggtg ccatcgttaa attcgaccat
    39301 caacaatatt acttgactca ttatccgatg ttgctcgggc ctaacgacac tatccgcaat
    39361 cttcatggac atatccatca ttacagcgta cctatcgaga acgatgtcaa tgtaggcgta
    39421 gacgcaccgg aaagagaact cttaaaggaa aaactaccat ttggcactcc gttatctgag
    39481 caacaaatca aagaaatcta tgaagcaaag aggaagtacg ataggtcgtg aaaaaactgc
    39541 cctatatcaa gtattaaaca aataaagata attactcata tttttcattt gagtaggctt
    39601 attgccacag gaacattagg atcagaaatg gagttgtaac aagacttctg tcacaactcc
    39661 attccatact attcgtcttt ttgctcatgg tgttctttta ccagtttttt ctgtaattct
    39721 ttatcataat ttcgggcagc tgacgttaaa aataaaacga ttccgcataa taaaatcccg
    39781 attccggaaa acaagaacat tttttctacc cctaaacgat cagctaatgg tcctgcaaat
    39841 aataatccaa ttggacctgc caggttcatc aaagagttga agttccctaa gacacgacct
    39901 aaaacattcg attcataact ctgctggatc attgccatca gcagtgtatt gaaatatggc
    39961 gttgcacaac ctgctcctgc attcaagata agaaagtaca agaacccttg actatcgttt
    40021 ggaaccaatc cgcttgcacc gatcgtcagg cccataatga tgtaggctat aataataggt
    40081 ttcattcggt ctttccatgt tcctataaaa ctgatcagtg caccgcctaa gagcattccg
    40141 actgcgtaga ctacttccac tgctcccgcc tgtccaacgg aaccaccaaa gtaatctagc
    40201 gtcatcaatg gatacagact gattgctggc atgaacaaca gcatcacaaa tgcaccattg
    40261 atcgttatgt accataaccc tttattatcc atcaattgct gcagcccaaa ttttgcatct
    40321 ttaaaaatag taagcggaac ttccaatatt tcaggagaaa cttttgggat cttcacaaaa
    40381 atcaataagc cgacaccaaa aactgccccc aatacatcta ataaaataag gtaattgaca
    40441 ggaacgactg aaaacaaagc cgcacctaga gctggcgcaa tgatgaaatt cgctgattgg
    40501 accattccta actgtccatt cgtccttgtt atgtgagaag atggaacgat tgtcggcata
    40561 atcgactgga tcgttggcat ttggaatgtt tgtgcgaccg aacgcataaa caaagacaca
    40621 aaaactagcc aaatcgggaa ggattctgaa atcgttccga ctactgctaa aataagcgcg
    40681 aaaatcgcta caataatatc cgtgacaatc aaaagagctt ttttatccca gcgatccact
    40741 agcggtccta caaatgggct tagtaaaacc atgggaatca ttcctagtaa agtagcaaaa
    40801 ctcaaaattg tcgccgaacc ggtttctctt gtcaaatacc agatgatcgc atattggacg
    40861 accatactag tgattcctga caaaaactgt cccgataaaa agaacaaata atttctcttc
    40921 caattcgtta aaacgaccga ctgttcattt tccataaaca tccctctttt ctttttcatt
    40981 ttgtatagcg tttgcacaac aatcattata cgggattctt ttttcaaaaa ataccttttt
    41041 ccctaaataa caatcgtttc aatttaaatt tctttactta gaaacaataa atcagcaaaa
    41101 tattaaaaat aacaacatgt gttaaattta aaaataaaaa agacaactaa tttgcgtcgt
    41161 ccttacaaag ttagtcatct aacaataggc cgtttcaaaa ctagttgtct ttttatatcc
    41221 acagatcatt cgactttttc gaataaccca cggctaatca tcccatccat cagaaaataa
    41281 aatttatctt ggctcatttt ctgttttgga tctttgaaaa tattgactgc tttcaatcca
    41341 tttgctgtag tgatcgacat tttcaatgtt tgaatatctt ttgatacagt gatttttaat
    41401 ttgaatcctt ctttgctttg cggcgtggca tctaatggtc ggatcaattg ataattgcct
    41461 ccgtttgttt ctgtaaatcc attatcgcgc aatgtatatc tttttgcatc aggatgcaaa
    41521 cgatagctaa ttggtgcgcc cagtaccgtt gctgttgttt caaatgccat gattttcacc
    41581 tcgataaaat tagtttctct ttattataaa agtttatcct gatttttact aggtttttca
    41641 gttaagttcc ctaaaaaatg aaggcgttct ctcagacatc tgttcatata agaatgactt
    41701 cactagttat tttttgacag cacgaactaa ttgatcaagg aaatactgga tgtcgtcttc
    41761 ggtatttccc aaaccaaagc tgatacggat ggattctttt agtatcggtg tatcttctcc
    41821 atacattgct tctaatacgt gtgaaggctc gatatttcct gctgtacaag ctgaaccagt
    41881 agaaatagcg accccattaa gatcaagctt catcagtagc aaatcatttg cttcgccaat
    41941 taagcgaaga ttcaacacat gagggagttt attcgttaaa tcaccattta cttgataagg
    42001 gatttcgttt gcttctaatg tatcaagaat caattgctgg aatcctttat atttgttgtt
    42061 acgtgcttca cgttcttcag gtgacagcag ttcaactgct tttgccatac cccagatccc
    42121 tgctaaattt tctgtacctg cacgccgctt ttcttcctgc tccccgccta aaagcaatgc
    42181 agggatattt actccgtctc gtttatataa gaaaccgacg ccttttggcc cattgatttt
    42241 atgagcagag atacttaata aatcgattcc taattcttct ggatggatcg tttggtttcc
    42301 gtacgcttgt accgcatctg tatggaaata agctggatga tccgctaaaa gttcaccgat
    42361 ttctttgatt ggcatcaaat ttccgatttc attgttcccg tacatcacag agaccaagat
    42421 cgtatcttct cgtaacgctt ttttgacctc ttcgatcgac agattccctt tttcatctac
    42481 aggcagatat gtaacgtcaa acccctttgt ctctaaatat ttcatggtat taagaacagc
    42541 aggatgttcg atagctgtag tgattagatg tctgccttct ttttgacgcg agaacgctgt
    42601 ttctaagata gctgtattat ccccttctgt tcccccactg ttaaagatga tctcgtgagg
    42661 ttttgcttgc agactgtctg caatgatttg tcttgctgtt tccaattttt catgcgcgtg
    42721 gcgaccaaat ccatgtatgc ttgaaggatt tccaaacgtg tcttgcatga ttgccgtcat
    42781 cgcttcaatt acttgtggat gcatgggggt agttgccgca tgatccagat aaatagtttt
    42841 cacttcattc atcccttcca aattattgct aggcacattc tagcataaaa tagcgaacaa
    42901 accaaagaag agctcatttt tgtctagagg acgtttcatg ggcatagaaa aaaggagctg
    42961 tgacaaaagt cttgtcgcag ctccttgaag ctgctcactt ctgtcacaac ttctttccct
    43021 cttttttttg tttattcgaa ttctttttct tccagacgga ataacggact catcggtgta
    43081 ttttcatgga tgcgtttgac cgcttcaccc attaattctg aacatgtaac gattgttaag
    43141 ttttctggat gacgattttc ttctgtgaaa acagaatcag tgatacaaat atctttgatt
    43201 ggtgcattgt ctaaaatact tttcgcatga tcggacaata atccatgtga cgcacaggca
    43261 tatacttctt ttgcgccgtt ttcttttaat acatttgctg ctcgtgcaag cgttgctcct
    43321 gtgttcaaga tatcatctac catgatacat gtctttcctt gaacatcacc gatcacataa
    43381 ccaccctcag ttgaagcatc atctgcatga tctacgatgg ctaatgtgct gttcaaatat
    43441 tctgaaagac tacgtgcacg ctgaacaccg ctgttttttg gcgaaacaac tacgatgtca
    43501 tctcccgtca gacctaattg acggtaataa tgagcaaaca acggcatcgt aaataaatta
    43561 tctacaggaa tatcaaagaa tccttgtact tgaaccgtgt gcagatctaa agtcagtact
    43621 cgagttgccc ctgcttcttc gatcaagtta gcgatcaatt tcgcagtgat cggttcatga
    43681 ggtttcgccg tgcggtcttg cctagcatac ccatagtaag gcaatacgac attgatcgtt
    43741 ttcgcacttg ctcgcttcat tgcatcgatc atgatcagta gttccatata gtaatcattg
    43801 acaggtgcat tcgttgattg aacgatatac acatgatccc ctcgaatact ttcttcgata
    43861 ttgatggaaa tctcgccatc actaaattgc ttcacgacgc ttttacctaa ttctgttccg
    43921 aacactttcg cgattttttc agctaatgga cggttgccat tcaaactaaa aatcttcaac
    43981 gtgtcatcct gatacttatt actcatgtag tcctccccaa aacttctcta ttcttcgata
    44041 gtttaacata tttttccaag attttctgtt aatttcagca aattcttaag gaagtgaaac
    44101 tgttccgtta ctccaactgg caggaatgac tttatgataa tcgccccagt tgtcgtgtac
    44161 tttgtaataa cgttctcctg tttcagtttc aaaataagcg tacgctgtca cccaatgatt
    44221 gccatatgta ctgccaagta ctttcaaaat accaatcatc acaggtttgc cttcacgtat
    44281 acgttttgta gctcgctgcc atgaacctag aagagttgct cgtgcacgct catgattgcc
    44341 attcttcttt aaaaaactag aaatccctgt actaacctga aaaggaatcg taggaagtcc
    44401 tagtggttgg atctggctac gcaatgcctt cgtcaaaacc aacgaatcag ccgtattttt
    44461 cttgcgaatc tcatttggaa gcatccaccc cttacgatag tcttgataat aggcaaggag
    44521 aactgctgcc gcgtaagtac cacaaagata gcctgagggg gtagcccatt tcttatacct
    44581 caaaaaacgt tcttctggca atcccaccca gcaatttgcg agttcctttc ctgacctttt
    44641 ttcttcgatc aaaacgggaa tatcttcttt tctgttgatc catctagata actcgattgg
    44701 ctcttcattg atcagcttcc attttttaca agaaagaccc tcttgataag tatattttgc
    44761 tggagaatat tctaccggat gtcctgattg atcgataatc acataacttt gatcttcaaa
    44821 aaccagagct aaaaaaagca atttactttt tcttgactgc agctgctgag tgctggctaa
    44881 ttttttaatt tttttatcta ctttgaaata taaaggttta tccactactt gattcagttg
    44941 ggatcgcctc ctttttttca ttataagtga aggattgaaa aaaacaaatc agtttgattg
    45001 ttcgaatttt caatttttta tgttctattt gttaattcct tcattttgta agataatggg
    45061 cacacgaaac aaaaaaggag cgatcgatga atgaacaaag aacgattgaa acaagatttc
    45121 tatgaagcag tcaatgaaga atggcaaaaa acagcaaaaa tccctgcaga taaaccagct
    45181 acaggcggtt tccaagattt agttgacggg atcgaccaac ttttgatggg agaaacagac
    45241 gatctgcttg cccatccaga aaaagtgtct tcagaaaaaa tgaaacattt ccttgcatat
    45301 tatcaactgg caaacgatta tgaccgaaga aatgagttgc atgctcaacc gcttcaacct
    45361 ataatcgaaa aagttgaatc attgcagtct ttcgacgaat tgaataagca atttccagaa
    45421 tggctgttgg atacattacc attgccattt aatctggatg tagatgcaga tatgaagaat
    45481 gcgcaaacga acgccttctt tgcttatccg ccttctttat tccttccaga taagacgtat
    45541 tatgcatcag accatcccaa cggtgcacaa ctaataggcg ttttctttga tatggctgtt
    45601 cagttattag agcttgccgg caaagaaaaa agtcaggcag aagcaatcac ggaacaagca
    45661 gtgcaatttg ataaattgat tgctcctcat gtaaaaagtg cagaagaaaa cgcagattac
    45721 agcaaaatgt ataatccgca atcttttgat acatttatta aatacacaga taaactggac
    45781 ttgaaaaaac ttgtcacggg tttgattggg acaactccag ataaagtgat cgtaactgat
    45841 ccagtgtact tcgatcattt gaatgacatc ctgacagaag ctcattttcc gttattcaaa
    45901 agctggatga tcattaaaac agtacgttct cttagtggtt atctatcaga agaattccgc
    45961 caagtcagcg gaatctattc tcgcgtattg tctggaacgg acgaagcaat gcctcagaaa
    46021 aaagcagcgt attaccttgc ctctggacaa ttcgatcaag tagttggcga ttactacgga
    46081 aaaaaatatt ttggcgaagc tgctaaaaaa gacgtagaac aaatggtgaa aaaaatgatc
    46141 gccgtttata aaaaacgtct agaagaaaat gactggcttg gggatgcaac aaaagaaaaa
    46201 gccgtcataa aattaaataa cttaggtatc caagtaggct accccgataa gatcccagca
    46261 ttattcgacc agttcaaaac agtacctgca gatcagggtg gtactttgct ttcaaatact
    46321 cttgttttca gcaaactcac attaaaagat cgtttcagca aatggaacaa accagtggat
    46381 cgttcagaat gggaaatgag tgctgacacg gtcaatgctt attatcatcc atttcggaat
    46441 gtgatcgtct ttccggcagc gatccttcaa gcaccatttt acagtctaga acaatcaagc
    46501 tctgctaatt atggtggaat cggagctgtt atcgctcatg agatttccca tgcatttgat
    46561 aataacggcg ctttatttga cgaatatggc aacttgaaca actggtggac agaagaagat
    46621 cttacacaat ttcaaaacaa agcacaagca atgatcgaag aattcgatgg tctgcctttt
    46681 gctgacggaa aagtaaacgg aaaattaacc gtttcggaaa atattgctga tgcaggcggt
    46741 ctaagctgtg cattggaagc agcaaaaacg gaatcagatc tttctatcga ggaattcttt
    46801 gtcaattggg caacgatttg gcgtacaaaa gcaaaaaaag aataccaaca acttttactg
    46861 caaatcgatg tccatgcccc tgctaaactc cgagcaaacg tgcaaccaaa aaaccttgac
    46921 gaattctatg aaacatttgg tatcacggaa caagacgcta tgtatctagc gccagaaaaa
    46981 agagtgcgaa tctggtaaga ggttgtgcca gaagtggtca gcttcaagaa ataagaagga
    47041 atttgggaaa atcgcttctc aaatttttgt gacatttcgg cttatttttc gaagaagtta
    47101 cttctggaat accatgtatt agaggttgtg aaaaagctgc ttagtttcaa gtagtaagaa
    47161 aaattttgtg aaaatggctt tccacatttt tgcataaatt tgacttacta ccgagaaact
    47221 ggcttttgaa caccgtttat cgagaggttg tgaaatcagc gtcctgacct gagtattaga
    47281 gaaaaaaacg gaaaaatagt tcctcatatt ttgccgtttg ttgagctaat accgagggtc
    47341 agctgattga acaccgttta gtggagagat tgtgaaaaag ctgtcctgca tcaagtaata
    47401 agaacagcca atcaaaagca gcaaggagaa cctcatctat aaaaagatag aaggaagtga
    47461 gacatctatt ggtctcattt ccttctattt ttactttcct cagtcaattg ttttacatca
    47521 taaaaggaga aattccactt atttttttcg ctgtttcatg acataaacaa ctacaccgat
    47581 taacaaaatt cctccagcta atgctagcaa cgggttatta aattctcccg tttttgggag
    47641 tccttgagtg ccattttttt cactttcttt tgctgtccta tccggatgag aaggttttcc
    47701 atttggtttt ccatttggtg attcatttcc tggattttct ctttctggtt tgtcattttc
    47761 cgggggcaca tcggcagttt ctcgcacagt gatcgctttt tgctgggtaa cagattctgt
    47821 atgagcagac catttttccc catcaaatat ttccgaacga taagtgactt ctagcgtata
    47881 ttctcctttt gaaggtgctg aaaaaatagc ggtatgatta gaaaattgag cacttgactg
    47941 tgtttcaacg atttggatct tttctgggaa ataacgcata tcttcaaaga caggcgttcc
    48001 ttgatttggt gtgaaagttg acacaaaaac tgtaaaaggc ttcagttcaa tgatatttcc
    48061 ttctgcattc tccgccacac catttgcttc ttgtataata atcggattat tttgttcatt
    48121 tggttttgtc tgatttggtt cttgtacgat tgcatactct ggatattccg aagacggtga
    48181 ggtttctccg tcaaaaatag cacctacaga taatggaaga ccatccactc tttccttttc
    48241 tgtttgacga ttccccggtt taatctgcat cagtccatga acatggatac ttccattttc
    48301 atagcgcgta acaggctgct gaccttcttt cgaacatgta tttagagact cgatccaatc
    48361 ttttgatatg gtatgtccaa gagtattttc tgattgtttc tctcgttcat tccaatagta
    48421 gttcaacgag tggtagattt gatcttcgtt ttgattcaat gggcggatct gctctctcat
    48481 ctcaagattc tctgttcgga aagataagat accagaagca tggtagtctg tgtttcctgc
    48541 tgaagaggta taaagagcca cattatatga accgttatta aaacttgtac tgctattgac
    48601 gataatatct gttccgctat tggaatcgat tcctttcgca agattttcga aagacaaact
    48661 attgatcaat tcatgagggc ccgttaaaga agaaccgccc attttgaatc cattaccgtt
    48721 accttctccc tcaattcctg gtacccagcc gtttcgataa gcaactgagt ttttgatgat
    48781 tacttttccg atcgaacctg tttcattttt agcaaaaagg tcccaaccgt catctgcatt
    48841 atgatacgcg atacaaccgt caaatacatt tccttctcct attgtcagtt tggccgcaaa
    48901 tccatcggca tcttcaaatc ctggatcggc attttcaaaa gatgtacagt tcttgactaa
    48961 gttatgcgcg ggccatgctt cgaaaggatc atttgagcta ccgctgattt ggattcctgt
    49021 atttccattc cgataagcat gaatctcttc gatcaaatta tgatttccag aaatctgtaa
    49081 tcctttttgc atagctgcac tatttgtaat gtcaaaccct cgtaaacccc agtagtgact
    49141 gaacagtgtc atcccatttc cagttccttt aaaatcaagt acaggacgct tgttttctgg
    49201 atttttctct gcaatcaact gaatcgggtt ttctcttgtc ccgttaacgc cttttggaat
    49261 cgtcaatcct ctttcgaagg aataagttcc aggcgccatg acgattgtct gcccagcata
    49321 tgcgtatctc aatgcttgtg tcagagataa tggattttgt ctgcttccgt ttcctgcatc
    49381 tgacccttct ggtgttacat aaactgtcga atatttaggt ttacggtagt ccactgtatg
    49441 aagaatctct tttgtttcat aactagtcat ctctacgtat tcttctggcg gatagttttt
    49501 atctggcgta aaactgaaag taaattcgtt cgttccttcc atcagttttg tctgataatc
    49561 aaattcccga ttcgcagtga tagccaagtt ttttgcgttc ttaagcacct ctcctgttgc
    49621 tttattttta attgtcaata atccgtcagc atttgctcta aaggacatag tatgatcttg
    49681 gtttcctgaa tgattactag aggtcacagt gtaaatcgga tcaatcaagc gagtaggtct
    49741 ttcttgccca ggaggatctg tcgcaggatc tgagtaagca acttcgattc cttctacctt
    49801 gatcgtcata ttccttgctg cagcaaatcc tgcataaata accgattcat ctgaagcgta
    49861 taatttttcc cagtcataca tgatgtcaga agccatttct tctcctgttt caggatcgta
    49921 ataatatgcc tctaaaccag tattcgtttt tttcatctct acgtccagtt tagtaatcga
    49981 gttcgtggcc ggaaacagat tcccatgacc gtttccgaat atattataag aacctgtttc
    50041 tttttccaag aaccctgctg aagtctctaa aggtgttgtt tccactgaga cactcccagg
    50101 agctggcgca gcttgcggat cttcagatga tattcctgtg attgcccgtg tccccaatcc
    50161 aagtcgcatc gtatatttgc tgccgctcgt gttgaccact tcttgtctat ccgagtccca
    50221 gacatattcg atccgactgc ctagtatggc aaatgaattt gaataaaatg cctgcccaaa
    50281 caaatgattt tttggtactg cgtctcttac cattaaagca aatccttctt gggcattcgt
    50341 ataggtccaa gattctattt cgatcgtcgc ccgcatccta aagttgatgt ctttggggat
    50401 tgcttgataa taataggtca ttccatctga tccgcttgac tggaattttc cgccgttatt
    50461 cgtggaagag agccgcacgc cgtcttctaa tggttcaatg gcatacctac tagcacttgt
    50521 gctttctccg aaaacaaccc ctttccactc ttcatttgct tcttcagatt gcttttttgt
    50581 cttttcattt tctgattctt tcatcatagg atcatttcct tcttccgtat ccatatcttc
    50641 actagttctt ggtatttcct ccattgttga catcccttca atgttcacgt gtgcattttc
    50701 ttcgttcaca gactgttgtt cgttagcagc aacttcaacg acagaaatta aaaccggggt
    50761 actgagcata aggagattca tcattagcgc actgtatttt atacgttttt ttaacaagtg
    50821 tattcctccc gtaacaaatt agaaagcgtt tacttaaagt attacctaat ttatttttac
    50881 tgtcaataaa aaacaaaatt ataataagtg tattttataa aaagaaaaaa tataacttaa
    50941 gttgttgata ataaagagat ttattaacgt aaaaagaata agttttttta aaataacgta
    51001 taaaaaagag cataaaacaa agtcgtttgt tttatgctct tcttttatta ttttgtgctt
    51061 tttattttat caaatcactt tgttttttta taaaatttct gcgcctagtg tggactcaaa
    51121 atgtctcaat gcccattcat gtccaacggg atcgaaactt gccacggcat ctttgaaaat
    51181 atggagtttg tatcctagat tatacgcatc gactgctgta tgcaacacac agatatctgt
    51241 acatacgccg gtcaaataaa tatctgtgat ctggcgttct cgcaaacgga tgtctagatc
    51301 tgttccacta aaagcggaat aatgccgttt gtctatccaa taaacatttt cctcttgctc
    51361 atagtcttgg tataaacttt ttaaagagcc gtacaattcc cgtccacccg ttcctatcac
    51421 attatgcgga ggaaataagc ggttctccgg atgaaaggaa tcttttggat catgcgcatc
    51481 aatggcaaaa acgacaaaat ccttttgatc aataaacttc tttgtatgag cagtcagctt
    51541 tttttcaatt acttgtcctg ctgtcccagt agtcagcttt ccatcctctg caacaaaatc
    51601 atatgtgtag tcaatcgaga tcaatgcgtt catcttagtc ctccttatac gagatgtttg
    51661 acaaattcga tcaccatttc tgctgatcgt ttgcctgcgt cttcgataaa ttcgtcaaag
    51721 ctttgtgtcg ccgagtgatc tgctgtgtcg ctcattgcac gtacgatcaa aaatgggata
    51781 ttgaactgac gagctgtttg tccaacagcg gctccttcca tttcgcaagc taatgcttca
    51841 gggaaattcg ttaagatttc tttgatttta tctggcgagt cgacaaatgt atcacctgta
    51901 acgatcaatc cttcttttgc gttcaaattc gttgcttttg ctgctttaac catttcactg
    51961 cgcaaatatg tgcttgcttc ataatataga ggcattcctg gtaattgtcc tgggttgtag
    52021 ccaaatcctg ttgcatctgc atcaaaataa gctactttgt ctgatataac gatgtcacct
    52081 acttgtaagc cttcaccgat tccgccagct gaacctgtat tgatcaccat gttcacgccg
    52141 tattgttgga tcaacagact tgtggtaata gatgctaaga cttttcctat accggaacgt
    52201 acgacgatca cttcgtggtt acctaatgaa cctgaaataa ataaagcgcc tgcgcgttcc
    52261 catgataatg gttcgcttag gttctctctc aaaattttta cttcttcttc cattgcgccg
    52321 ataataccga ttttcatctt tttaattcct tctttctata taaatgcgat tgctaaaaaa
    52381 accacacata acattaggat aacaataata agagatttca tcaaaaaaga gttccatttg
    52441 gtcgtctttt cccgttcgct gatccttgtt ttcgtgattg gtttattctt tttgctttct
    52501 ttacgataaa agctggcaat ctttttttct tcttgctgat aagctgtttc tgcttttcgc
    52561 tgttttttta atgactcgct tgcttgtgct tgttgtcgct tgcgaagttc gcttcgcgta
    52621 ataagcggtc ctttggccat aagccgatcc ctctactttc ctttggtcaa tagttcccag
    52681 tattgaatcg cataaatcgt ctttgcatca caaatcaact gatctttcat cgcttgttgc
    52741 gcctcttcaa gagttagatg atacaactcc agtacttcgt cttcatcttg tgctaaagga
    52801 ttctcgacct tctctacccc ttgtgcatga taaatatgaa ggacttcatt tgcaaaacct
    52861 ggtgaaagat acatcgaagt aagatggctc agcgacttcg cacgatagcc agtttcttct
    52921 tctaattctc tagctgctgt catttcggga ttttgtcctt ctcctggatc gatttttcca
    52981 gctggaatct ccaaaatcac tttttctaaa ggttttcgaa attgtttgac aagaagcaga
    53041 cgatcttgtt cgtcaaaagc aatgatcccg acaccgccag gatgaaatac cagttctctc
    53101 ttcgaagttc ctccatctgg caaacgaact tcgtctacag caacatcaat aatttttccg
    53161 ctatagattt ctttgcgact gattgttttt tcttcaaatt gctcattgtt cagcatatct
    53221 tctcctgctt tctttgtaat cataactgct tttttttcat ttttcaattt ttctcaaaaa
    53281 ctccttatta gtttaccata gataaacctt agattttctc taaatataga aaatccttct
    53341 ttagtccgat actctttata gtagtccgta tgctaaaata agtatgtaat cgaataacga
    53401 aaagaattca atactcaacg ataaatgaca tggagggttt attatgataa aacgaaattg
    53461 gccgtggctt ctagcattgg tcttgctatt tctctttgtc cgaaacaata gtttttcttt
    53521 tgttctagga cttttattga taggtgtagt tttagttttg tggggactct ttggttcgcg
    53581 caggaaaaag ggaaaacaag aagaaattcc tgcactgact gacgaacttg aaactcacta
    53641 tgaaaaaagc ggtatgacag cgaatgaaat ttcatttttt cgacaaacaa tgaatcaaac
    53701 aaaaaatgag atcaatcaat tgcaaatgaa tatgcagcag acagccaaac ttaaagcaat
    53761 cgatctccgc catgatccag tcaaagcagc gaaagcttta ttcaaagaat tggtgaaaga
    53821 accaaaccga ctgcatgaag caagtcagtt tctttatacg catctgccga atctagttga
    53881 tttgacaaat aagtataatg agatcaatga ccatgagatc aaaaacaaac agacctatga
    53941 aaaactagaa gaaagcgcgc agatcatcga ccagctgtca gctttaatcg cacaagatta
    54001 tcaaaaattc gttgctgagg atctagatga tatcgacgta gagatatctg ttgcgaaaca
    54061 gagcttaaag cgtgataata aatatgaacc agaacaaaag gattaactct tttgttcata
    54121 aaagaagact cggaacattc agatgatgtc tggctgtttc gagtactttt tctaaagtag
    54181 agacattcat gtaagaatcg agaacagatt caacaaggag gaatttttta tggatcataa
    54241 accgactgaa acaaaagatg ttacaccagt taacgataca cttgaagatt tattgaacaa
    54301 cccgttttca actccaacag atacgctgac cacttcacaa caagcggaga ttgatcagct
    54361 ccaagagcaa cagacagctg ctcgtttaat tgacaaacta ccggcggaac gccaagaaca
    54421 agctaaacag ctagcagcaa aaatcgatgc taatgatgca cagtctgtca tcagctacgg
    54481 atcggctgcc caagcaaaat taagtgaatt ctcacaatcg atgttgaatc atgtgcaagc
    54541 acaagatatt ggtcctgtag gagattcctt aactgaactg atgtatcgtc tccaagaagc
    54601 caatcctgac gaactgcgtg ccggagaagg gaacatcttc cagcgtgtct tcgggaaggt
    54661 caaacaatcg atctatgaag tgacagcaaa atatcaaaag attggtgcac aaattgacaa
    54721 gatttcagtg aaattagata aagaaaaaga cggtctgcta aaagataatc tgatgttaga
    54781 acagctttac cagaaaaaca aagactactt tgatgcactg aatatttata tcgctgctgg
    54841 agaattgaaa atggaagaac ttcaaacaac gatcattcca gaagcgatga aaagagcaga
    54901 agaaactggc gatcagatgg atgttcagat tgccaatgat tacacgcaat tcctagatcg
    54961 tctggataaa cgtacgcatg atcttcgctt agctagacag atcacgatcc agcaagcacc
    55021 acaaatccgt ttgatccaaa acacaaatca ggccttggct gaaaagatcc aagcatctat
    55081 cgctacagcc attccgctgt ggaaaaacca agtcgtgatc gcattgacct tgcttcgtca
    55141 aaaagatgca gtaactgctc aacgccaagt ctctgaaaca acaaacgact tattgaagaa
    55201 aaattcagaa atgctgaaaa tctcagccat cgaaacagcg aaagaaaatg aacgtggaat
    55261 cgtggatatc gagacccttc aaaccactca aaatgatttg atcgaaacaa tccaagagac
    55321 attgcgtatc caaaaagaag gaaaagaaaa acgtcgtcat gcagaagtag agcttggaca
    55381 catggaagaa gatctgaaac aaaaactgtt ggatttaacc caatagatca cctttcgctt
    55441 gttactaaaa caaacgccca acaacagttt attacaactg ttgatgggcg tttttcttat
    55501 ctttcttcta acttctccat tggagtctat ttctcattca tcttgctgtg tccatagcca
    55561 tagccaaaat aaatgatcag tccaataacc attacgatac cgaacacgat ccatgtcaca
    55621 gtttgcagac gaagcatcaa tacaatacaa gtcaagatgg agacgattgg caatagcgga
    55681 acgaatggca ctttgaattc tccagctttt ggtttgccaa acatttttct caacttcagt
    55741 aagcctagac taacaagcat caaataggcg agcgccatga tattcgttag ttccgctaat
    55801 acattcaatg ggaaaaatcc ggcaaagaat acagctgcca caccagcggc ataagtcgct
    55861 tttttcggtg tacgatgctt ttgatcgatt tctgtcataa acttaggaag taagccatcc
    55921 ttgctgacag caaacagtaa acgagcaagt gaatacatca tcgagatcgt taccgtcagt
    55981 agcgttaaaa ttgcccctac agcgatcacc gcgcccactg ttccatgtcc tacatacctc
    56041 attgcaaaag ccactgggtc attgactcct agttcagtat acggaacgat tcctgtcaag
    56101 atcagcgtca cgatgatgta aaggacagta gcaatcagta tcgaaccaat gattcctctt
    56161 ggcacatctt tttgcgggtt tttgacttcc tcggctgcca ttgcaacggc atcaaatccc
    56221 aagaaagcaa aaaacacaag agctgcacca tctagcacac cggaaaaacc aaaaggcatg
    56281 aatggctgcc agttatcagg tttaacgaaa aatattccta caatgataaa caacgcgatg
    56341 ataccaaatt tgacatatac catggcatta ttcaaacgta atgctttctt ggcttcaagc
    56401 gacacgatgt aagtgacgaa tatcactacg agcaccgcaa tcaagtcaat gtatgtacca
    56461 ttttccggat tgtacccgcc agttaatgct tgtggaagtt cggcccctaa acttttcaaa
    56521 aaaccttgca tatagccaga ccatccggaa gcaacagagg aaaccgctag taaaaattcc
    56581 ccgatcaaca accaccctgt cagccaggca gcaaattcac caaatacaac atacagatag
    56641 gcatatggcc caccaatcac tggcactcgc gaagcaaatt ctgcgaaact tagtccagac
    56701 aaaatgacaa cgattgcagc taagacaaat gaaagtgaca gtgctggacc agcattttga
    56761 ttggccgcaa cccctgtcac cacaaatatt cccgtaccga tgatcgcacc aattccaagc
    56821 atgatcaaat cagacgtttt tagttctttt ttcatctcac tcgtatgatt gagattgatc
    56881 tctttcttac gaaacaaatc cattgaagtt cctccccatt ttaggttgga aaacagcgat
    56941 taaactgttt tcatataccc taaaaggata ccacctaaaa tgactaaaag gcaaccaaca
    57001 ataacataaa tgagctcttt tttcgttttt ctttcgccaa ggatgaaaat cccacctaaa
    57061 gtagagataa tgatccccat ttgtgaaagt gagaagccaa cagctaaacc aagtgatttg
    57121 actgttagaa gcatgcagat gtttcctaag ccccataata atccacagat catgtttttc
    57181 cacacaaact gatcgacttt aactttacgg aaagcaaaga agcttgcgcc taagatcatt
    57241 ccgatacttt gaggtaagat aattgacatc gcatccaaat tcgcccagtt gacgatgatg
    57301 gtatatacac cataaccaat cgtagagaag atcaatgctc taaaaccctt accaaaatca
    57361 agcattttat tatctgtatc tatttttcct tcgtcatctt gtcgggcagt caaatacgca
    57421 ccgcttacaa gaagagctaa agcaataata ccgtatacat aatctttcgt ttgtgtccat
    57481 tcatggaaga aaacggctcc cgcaatcgta ttcaaaatta attgaaaacc agtagacaat
    57541 ggtagcccta cagaaacacc catgtacttc attccatgga actgtccatt ttgtccaaca
    57601 ctccaagcta agccggataa aaatccgatc aagaaaatcc aaggggtgat tacaggacta
    57661 acaacgaaaa agacaactaa agaaaacaga aatgcaccga tcgtcattcc tagtgtttgt
    57721 tgattggcat cgccaccaat tttaccactt actaaaccaa tactacccca tgccaacata
    57781 gggactaatg ctattaaaat ttccataacc aatctccttt tatttcacat gataagaaac
    57841 ttatcagcga aaacgttaac aacacaagca ctttttttcg tttctaacga ttttctaacg
    57901 tttttcatta taaaaattta agattgggaa aaataaagtc attgttgtcc cttttccttc
    57961 agttgattca gccgtcaaat ggatacctaa tttttcggcc agattttttg ctaaataaag
    58021 tcctaatcct gttgaatgtg ttttgctaag tcgaccattt ctcccagtaa atcccttatc
    58081 aaagatccgt ttcaagtctt ccgctgggat accgatccct gaatctttaa ctgaaaggct
    58141 gactccttgc gcttcctttt ctatgctcac aatgatgttt ccgtgatccg gcgtatattt
    58201 gatggcatta ctaagcaatt ggttgaagat aaaagcgatc catttagcat cggtcaaaac
    58261 agtatgatcc tcaccaacga tctcgtagcg aatatttttt tggataaaat aatttgcctg
    58321 actgcgtatc acaggctgaa tgattccttt tagtccatat tcttggatga ggtagtcccg
    58381 cgagaaactg tcgagtcttg cataatacaa aacttgttct acgtattcat cgatttttga
    58441 taattcattt tctagtaatg tatacttttg atcgtcaata tcgaactcga tcgaacgaac
    58501 tagcaattta gaagcggaaa gtggcacttt gatttcatgg acccatgagt caatataatc
    58561 tttttggtct tgttgattac tgattgctga ttgcattact tcttggtgtt cacggatcag
    58621 ctgattgata tattcttcta ccagtttttc ttcttctgtc ctcccaccac tcaaataatt
    58681 ttgcaaaggg gaagtttttt gtatgtcggc taattttccc caccatcttc tcttgctcaa
    58741 gtaaccaccc agcagataaa aaatcagaaa gacgccctca atcaaagcta aataagcaat
    58801 tgtgctcaaa tcaactttga tgtttggcgc cagccacatc acaaagatcg tcaatgcaat
    58861 aaaaaacagc catcccaaga tcaatgtcca ctgatctttc aaatatttaa aaaaattcat
    58921 cttaaccgct catcctttca gggaacgata tatccctgtc ctacttttgt ttcgatatat
    58981 ccttggatac ctgcctgttc gatttttcgg cgtaaccgat tgatgttgac tgtcaatgta
    59041 ttgtcatcta caaatcgttc gtcatcccac agtgctcgca gcaatttttc ccgacttaag
    59101 atctttccat tgtgcttcat caaaataaat aatagacgat attcattttt gctcaaatca
    59161 atgatctctc cgttgatttc catacttccg ttgtcaacat tcaacgtaat gccattgtgg
    59221 ctcatcattt cactagataa ttctgtgtag ttgtaagaac ggcgaagtaa tgcattgatt
    59281 tttgcaatca gtacatcgat ttggaaatgt tttgtcacaa aatcatctgc ccccatgttc
    59341 atagccatga tcatatccat attcgtattc ctgctggaga taaaaatgat cggtactttc
    59401 gatacttcac gtattttttg acaccaataa tagccatcca aaacgggaag attaatatct
    59461 agtaatacaa gctgtggttc ttctctttca aagtctgaga acacttgatt gaaatcggtc
    59521 gttccaaagg tttcaaattg ccatttctca agttcctcca tgatcaattg tcgaatgatc
    59581 tcttcgtctt cgactaccat gatttttgcc ataaaaaatc cctccatctt tcttcttgct
    59641 actacaatat caaagaagcc cttgtgaaac aagttggctt acctggaaaa tgtcatttta
    59701 gcaaacgtta aaaaaaactg gaaatatgcg atttaatcgc gtttgtctct tccaagcagc
    59761 ttaaatttat tatgttattc ttaataattg gtctattatc tgttattttt ctttcgttgt
    59821 ttttgtcttt taaattttcg ataacaccaa taaccgaaaa gcgttagcac tagcaatata
    59881 cctagaagga gtataagtaa tcgataaaga tggtattttt ttgtctgttc tatctttgaa
    59941 gagacttctt ctgtaaaggg aactcgtctt cctgtcacta gtaatcggtg agtgttcacg
    60001 gtgtaaggtg tacaagtgat aagtgtgact agatcctgct tttctctaat tgctaatgta
    60061 tttgtttttg ttggaaggac aacaattttc tcaacgactt cataagcgag catccgacca
    60121 tacacttcaa gatagaatcg gtcatcttgc tccatttctt caagatccgt aaagagtttt
    60181 ttctcagcaa taccgctatg ggcggtaatc acggaatgtg tactctctcc tccagttgga
    60241 aaagaggtgc cttgcaggac tgtcgctcct ctatctaaca aaagatcatt cgtttcatca
    60301 aataaaggca agctaacatt gattttcgga atatagatgg ctccgatcat atgttgttcg
    60361 taatattctt ttcctggatt ttggacattt ctaaccgctt gctcaaaagg atctttgact
    60421 tgtcccattc ctgggattac tgatgtatga gcaagcgtct gatttttctt ttcatgcact
    60481 gctaattgtt gctcatgttt ttcttcttta tcgcgttcaa gctgcttttg ataattctcg
    60541 atccttcttt gatccaaata attgctgaga gcatctgcta aaaatggata tgtaaaaact
    60601 gcagctccgg caagaaacat cactgccata aataattgta ataaaagact gatttgggtt
    60661 tgaggtctat tacctatttt ctttttcatt ttcttcacct tcttatttaa aaaaactgca
    60721 gcaaccttta taaaaccgat tgctgcagct tatttttgtt gcttatactt cagacttcat
    60781 tttagattta cggtaccagc tgtacgctcc aatcatcaaa cttattccga ttagtaagaa
    60841 tgccaagagc ccgttcccac cagtagcagg aagtgacccg cgtttcatat tcggtactct
    60901 ttctggccct ggattttcta ctcctacgat ctgaatttct tcattatagc ttccataaga
    60961 gatgataaat tcagtaaagg ctgcctcacc tgttggaagt acataacctt ctggcgccat
    61021 ggtctctttc atttgatagg ttccataatc taacccttga acctcaaagt atccatttcc
    61081 atctgcgaca aattctgttg cttgtccgct tgttgcccac tcaattctat ctgctcctga
    61141 ttcataaaca gctaaaggcg actccccttt ataaaatatt gcgtattcag aacggtcttc
    61201 attccacaat tcgaatcttg catctttaag caattcactg cttgatgcat catatttttc
    61261 aaactttctt ccacctgttg tgactttctc tggcggctct actccttctt cataatcaaa
    61321 ttcatcattt cgtccgattt caataaccgc tgtgttgtta tggaaatcat ccgcttctag
    61381 ttctgtggaa accttcaaat tatacgtgat cgttaaatct cctccacgtg catctgctaa
    61441 tctacctaaa gtatctactt tggctactcc attttcttct gtcaaaatcg tcacgacaaa
    61501 cccgttgctt actacttcta ctatataatc ttgtcctttt gttaaaatcg tctcgccggc
    61561 tcgcacttct atttcctgat cataataagt tagaccaact gtaggcgtat ctgtgatttt
    61621 gtaatttttg ataacagcgc ttccgttttc aaggacagaa tcgatgaaat aaggaatagg
    61681 tgctgtgatc gtgtaagaag ccgtttttcc tctttctaga tcaatataag aaatcgtttc
    61741 ttgttctcca gcttcattaa taatcgttac ttgtctaagg tcgctttcct ctacattcat
    61801 ctgtttatct gcttctctga tttcgttttt cggatacaaa tgcacatctg tattgtatgt
    61861 gtctttccat gtagaaccat cccacacgcc atccaccata tcaggcatca tcactggcat
    61921 cataacaacc attggagacg cgattctgga aatatgagct ggcgaataag tttctaagaa
    61981 aagatagact ttatctctag aagaaggtgc ttcttccgtc acttggacgg tagagaatac
    62041 cgcttctcca gcttcattcg ttgtttgttt gtcaatactt gtcagtcgat attttaaaaa
    62101 ccaactttct gtgtgccgtt tttgaatcca ttcaatcgct tcggcagaat taagaccgtc
    62161 ttctcgttcc ggtgttaaag gattatctcg aatcaaatcg taatatactt ccgttacgtc
    62221 aaacaaatca aaatcgactc ctggaatatt ttcttcacca aaatccgtag aaaccaatcc
    62281 gctattcggt cgttcttccg gaacagatga gaaacctttt ttgtgtaatg taatcgtcac
    62341 ttcacttggt ttttgtgcga cttcttcggc tttgactagt tttccgttcc cgaaaatccc
    62401 tattcccgca gtaacgagta acagtacact cattcccgtg acaatcattt ttttattcat
    62461 ttttttctcc ccgttctttt tttattaata aaacagcacc taacaataaa agaattccta
    62521 gtaaagaaat caacgttctt gcttcattcg tttgcgggaa tacggaccat tttcctgatt
    62581 gacctggatt gcttggacca ctcggctctt tcggtttgtc cgttgtttct tttacggtct
    62641 cgttataaac acgtggtgtt gcggattcat aggcagagac tggaactttc ccggattcta
    62701 attcagccat ctcctgtccg ttaactacta catattgtgg ttggcctttt gcatccaccc
    62761 aaaattcagg gatgatgacc tcgattctct tacttgcttc atccatctcg taaccttcca
    62821 caccttttaa ttcttcaaaa taataggtgc cagaaggcaa gaaacgttgt cctgtcgtaa
    62881 caaggccctc tttatccgaa atgaatttgc ttacattttt gtcattcaaa ggatcattgt
    62941 ctgctggttt gatccattga tttttcaagt cattagcagg agccatatct aaataatatt
    63001 tccccccttc tatcatctga tatagagcaa aaacagcacc ttctaatggt tttccttttt
    63061 cagttgttcc tctttgacgt ccatacttga agaagtatgg atctcttaga taaccgacat
    63121 ttttaggata gatatgaatc tcttgcagtt cctcggttga ttctgtcggg tgataaattg
    63181 gcaaaatagc agcaattggg atagctgtct gatcgatatc aacatccaat ccaacttctg
    63241 gatcaatcga ttcttcgaaa atcaaataaa ctgcatcccg atcttggttt ttcttaggtg
    63301 ctttgatacg tgcaatcccg tctcctaatc cgccaaccgt atctttccca gttgttaccg
    63361 aagtccctat ttggacaagc ctttcttctg tgattagctg acggatattg tttctgttcg
    63421 tttcagcgat ttgctggacg aattctttag gagtcatgtt ttcagcagct tttttttcat
    63481 gataataatc ggtcatgtcg taaatggcaa atgtcgctcc atttagtggc accgtctgtg
    63541 aaatgatatc tgctgtttcc cctgcttcct cagagatagc caagccatca ttttcatggt
    63601 attcaaattg atcgttataa tcgatatctc gaatcatccg tttatgcaac acgaattcca
    63661 cgacatcttc ccctgattct tctgccgaca tcgcatgtgg aagaaggact gctgcaagcg
    63721 gtagtaaaac aagtaattga agcatcaaac acaacagctt tttcattacc ttgctccctc
    63781 ctttttagat tgtctgacaa acaaaccata ggctgctcct gcaagcgcca tgaagaatgc
    63841 agcaagcagg atatagaata atcgtccgga tcctcctgta gcaggcaacg gattttcagg
    63901 atcgttcccg acactaagct gtaatctgat tcgatttgtc tccaaaagtt catattctaa
    63961 ctcttgctgt agatcaggcg tctctgcttc ttcgtttgga taatacgaaa tctcaacttt
    64021 tagtgtaccc gcttcttttc ctggaactac ccgatcattt tctatgtcag gttcttctcg
    64081 ataactaatt tctaaaataa agtaacctgg aagttttcta tagctgtcag gtgacttcac
    64141 ttccttgatc cgatagaccc cttccaacaa gtctgaagca ttgaataggg aagaatcgtt
    64201 tggatctggt gccaagcctc cctcgatgat ttcatactct cctgcactat tttgtttctc
    64261 aattgaaaat tctgcgcctt caagacgtcg gctattcata ctgtcaattt tcaaaagttc
    64321 caaatcgatt ggcgctagtt catcttctaa ggttacttgt agtacaccat cgatgatttc
    64381 atagccttcc ggcaagggag cagtttcgtc ttcgatgacc gtatcttcaa tgataaactt
    64441 accttcttca ttcagtgcaa actggaacac ttgatcagat agccgatacc catttggtgc
    64501 gacagattcc gagacctcat attcaccaat agacagatgc agaggttggt cgtaatttaa
    64561 atcgacatac ttttctactc ctacggcacg agaatagaag tatccgatcc caggcaaacg
    64621 tttcgattct tctggttcta acggattacc agtgtatgct cgatacagcg ggaaggaaga
    64681 atcccccact ttcctgatat cgaaacctgc accatctaat gtatggcctt catggtctaa
    64741 ttttctaact cggatctccc gataatcaaa cgtattgtaa gcagtgaatg ctacccataa
    64801 acgatcctct tcatctgttg tatacgtgag atattgccaa ttttcttcac ctgtttgctt
    64861 gagttggata gtccctatag cattatcgta aagtcgcaag atccatgtgt cattttcatc
    64921 aggttctttg aaaccttctg ggttctggct ctcaatgatt ttgtattctg catagttggt
    64981 agtttcttca ctatccttat aaacaaatga atctggctct ccgattggat gaataacttt
    65041 ctcaccatcc acgattacat atttcccgtc ttcatctact gaatagaacg tgagtctccc
    65101 tttctcttcc tctacttcgt tcacaccaga aagccctttc gctactggat atccgatttc
    65161 cagtccgtta ccatctgttt cataaagttc aaactctgcg ccattgattg gcatattact
    65221 gccttcaatt agtttattga tattcatgtg gattggcttg aattcatttc gcatttccag
    65281 tttgacatac aactcatcat actctgtgcc ttctatgtta ggctcttgta caacagaaag
    65341 cttgtgatat tctccttcat aataggaatt cggatcttta ccttccggtc cgccgactct
    65401 cgaaccagat gtatattcat ctacaagctc gtagtgacct aacatctcat cttcgttggc
    65461 tgcatatttt ttgatttgga attgatacgt ctcatctact aactgataac gtggtggtcc
    65521 agcgatctct ctgatccaaa atatgtcgct gactgctcca gtttcatctc ctaaaatcgg
    65581 catcttcgtt tcaaagatcg ctattccgtc cgtggtagtt ttacttgttt cgattggttc
    65641 ggcttcccca ctctctggat tttggtcata taatgcaaat tcgactccag ccaacggctc
    65701 gccattttga cccttcttgc tgacttggaa attacggcct ttatgttcgt aacgaatgga
    65761 agaagatggg aaatacatcc gtccagtagt gatatcattc tcataatcct ccaggttctg
    65821 aatataggcc atattgttca ctgtgcaaaa atttccgtct tgagctcccg catcaagttt
    65881 tacttggtac ttgatcctga ccatttcccc ttcacctaaa gaaatcggag aaaatttata
    65941 agcttggttt tcccgtccga catacgttgt cggagtcgcc actacttctg gtggggcttg
    66001 tccatgacgt tcttcatccc atatttctgg ctcttggtac ttcatgccgt tttctcctgg
    66061 atctagatgg taaaactgaa tatctgccga tctgccagct ccaaatggtg agacattaaa
    66121 accagtttca tcataaagtg tggcttgctg gatcgttctc ttgaaggtag aagagatatc
    66181 ctccaaggct gtaacaatgt cattcttgtt gttcgcattg taatatcgcg gtgttacgcc
    66241 atcttcttct aaatcagcaa tatttttcaa tacatttcgt ccaatagcat ctagtcgttg
    66301 tctcccgcta acgtttccat cgattcctaa accaatggag aagatacttg gcgggttctc
    66361 ttgatacttg tttttcagcc aatgatgata agcaactgtg ttgatcgcag atgacttttc
    66421 ttgcgaagta ggactgccat tcgtattgtt attagaagaa ccatcaccaa cccagtgagt
    66481 cgctttatta tctccttctt ttacctctcc ataacgatag tgtacattta cttcatcttc
    66541 tggacggtta aagtcagatg cataggtaac tggatgagta aaccctgcat tagaagtatt
    66601 cccagaaaac tcctcaaaat ttctgaacaa aacgtcatta tcttcagcaa tcttatcttc
    66661 catcacagtc cagttgctcc aagctccatt agtgctcgta cgataacttg actgaatcgg
    66721 tgcataactg aaggtcggtg tcccatctcc cacaacgatt aggatttttt ctggatttct
    66781 attttctccg ccattgtctt tatacaatgt ttcatagcca tttttaagcc ctagtgtaag
    66841 cggagttcct ccgattggtg tacgatttaa tgctgtattc tcacttcccg tcaaacgatt
    66901 gatatcattt gtcaatggaa agatgtccga actgatttgc tcatggttat tgatagctgt
    66961 actattatgg taaaaattca ccataccgat tcgaatatcc agactcgggt cagagagcag
    67021 atctttactc atttcgttta ctgcctcaat caacgcagca tttttagttt gactattggt
    67081 cccagcggtt aattcactca tactcgctga cttatctaga acaaaaacga tatcgattgg
    67141 actgatttcc tttttctcgc ccccgatgac atctagatag acattgtaaa gggttgttgc
    67201 atcttcagga tgtagatcag atgctgtgct gcttggcaga acaggttcta cccatttttt
    67261 gatgtacgcc ccgttataat ccaagtaact gttttcaaaa ttccgttcat ttccccaaag
    67321 ctgaacggtt tgagctggaa cgtttctatc ttcttcgcct gcagttgatc cattattagt
    67381 agcatagtcg taatttcgcc agttcgctcc cccgtttgta taatcactat catcgatcaa
    67441 gttctctccg tcatatggcg agcctttgtc tccttgatag cgttcattgc tttgtgtcca
    67501 atttcctaac acttttgtat agtcattcgt tgtaaacttc atctattctt tcatcaacca
    67561 ccacttgaag aggtagttac ccttcgttca catcggggat cttttctgtt tcaaaaatca
    67621 atgtgccggt ttctgcttct tttgaataaa cttttccgac ataccattct tgaccatcga
    67681 tcgtctcgac ttttaggtct tctccatctt catcatagga ggatagacct gttccacgaa
    67741 cgttttttac ggtaccaatc ccggcggctg ccgcatcgat tgctaaacgt attctacctt
    67801 cattggcact ttcctttttt tcaaaagcca gatgccattc aagggtttct tctttttcaa
    67861 tatacttccc ttcaattttt gcatagtcct catctaagaa tacctcatcc tcctttgttt
    67921 ctgttgactc agcagctaca tccagggtcg tcatatgata gactgactgg aaatatggtc
    67981 caaatagcaa actgacagtt actaactgca aaagcttcaa ttttaaccct ttcacatcct
    68041 tatactcctt tcaaaaatat ttgtcttctt tcacaacaat caacaaaaca atgcccatct
    68101 aattataatt taatttaatt ttaattttaa atcaaatgat atccttttta gttaaaaaac
    68161 accaattata caacatttat tattaaaatt aaattataaa attttataac gttctcattt
    68221 aacaaaactt aagttattaa gacaaatgaa taaacaacta cgctttcctc gaaacaaaaa
    68281 aataaagcac aaatgcgcat ttacgcactc atgctttatt cgtacaatta attcagataa
    68341 cggcagcgca taggatgcca ataacacttc ctaaaatagc tcctcctaaa atgtcagtag
    68401 gataatgtaa aagtaaaaaa atcctcgaat aagcgatcaa acaagcaaat aaaaaggcta
    68461 atattcctgc aactggactt aattcgaaca acgcagctac tgataaaaag gctagcgctg
    68521 tatgtcctga aggaaaagaa gaagtcttcg gtttacttgt gtaaaggaca agccgacgat
    68581 ttttttcata aggtcttttc cgtcttgtcg tttttttgat aaaaagcaaa ccaacaaaaa
    68641 aatagatcaa actgccgata agaatggcta gaccatattc tctagtatca ggtatcaaga
    68701 ctaaaacagc agcaaggagc aaccaaataa aaccaccatt agagatatta ctgataaatt
    68761 tcaaaaaatt gatttttcga ctatccgttt tccgttgctt ggcgaacttg ttgataatac
    68821 tatcatcgat tttagcaatc aaacgcaaca tgttattcct cctttttaag aaccttttct
    68881 tgcgtacgat ggataaaaag caggacttga aaataaaaca agaaactgaa acctaataaa
    68941 gcaaaataga ttggtcctgc aaaccagaat gcgacaagaa ggatcaacgt gcctgccaaa
    69001 tagaaaagcg cgcttttgaa atcattaaaa aacaagaaaa atgcagtaat ccaagaagct
    69061 tctttttgtt ccagttgaag caagattttg taactaaaga gaagcgcgct taatagaagc
    69121 aaaaacaacg tagtatacat caatgtatag ccaattcccc caccccaata gcggaaaatc
    69181 tgataatcga tcaatagaag aagaaaataa acacttgcta aactatcttg ctttccataa
    69241 aaagagaagt tctcacgaaa ctttttccag aatagtgaac cgagcttttt ctcttcattt
    69301 tttttgtaat gataaatcat atacagaact gttcgacttg cagttcctaa tgtgaaaaca
    69361 ggcaagacgc acaggaacca tagtagctgt aaatggataa gacgtggaat ccattcaatg
    69421 atttctaaga aataatcatt ggctttttta ccaatcgatc gattcatcat ccttttgaac
    69481 ctcctgtcaa atccatccct tcaatgaaat aacgttgtgc aaaaaagaac agcaaaatcg
    69541 tcgggatcaa gacaagtgtt gctcctgcca tcagataatt ccattgtgtc gttgcttggt
    69601 tctgaaaaac ttgcaagcca atctgtaacg tgtatttttc ttgatcttgg atatataaca
    69661 gaggacctaa gaaatcattc caagctgcgt tgaaggaatt gatcgcaatg gtaatcaagg
    69721 caggtttcgt caatggaagc atcaaatgac tccaaatata caaatgattc gctccgtcga
    69781 tttcagcagc ttcgatcaat tcattattga tcgataagta aaattgacgc atcagaaata
    69841 tattgaacgc attgccgaag aacgatggaa cgatcagggg caaataagta cctacccagc
    69901 cgatcttgga gaataataca tattgaggga tcatcgttac aaaccccggg atcatcatcg
    69961 tagaaagaac caaagcaaac atcagctttt tcccaggaaa atcaagcttc gcaaatccat
    70021 aagcaataaa agaatttgaa aggacattac cgatcactac tagcacagtg atgaataatg
    70081 tatttcttgc atagcgccaa aaaggaaagg cggcaatcgt atccagatag ttttcccata
    70141 cgattttttc tgggaaaaag gtcggaggat aacgaacgat ttcttccatt ggtttcaatg
    70201 aagtaaacac catccaaagc aatggaatga tcaaaatgat tcctattact gtcatgagga
    70261 cataacttag tatttttttt gtttgccgat tcacactggt ctttttgaaa taatccatca
    70321 tttgccgtca cctccagaat aatagaccca cttaggtgca agcttcaaat tgacaaacgt
    70381 cagaaccaac acgatcagaa acaggatcat tgacatagcc atcgcataac ccatatcaaa
    70441 agctacgaac gccttgttcc acatatgcag attataaaaa agcaaagaat ttgcaggtcc
    70501 gcctgttcca tttttcgtca tgacataagc ttcttgaaaa atttggaaag aaccgatcgt
    70561 agaggtgatc acatcgtaaa aaataatagg agtgattaat ggcaaagtaa tacttttgaa
    70621 ctttccccaa acgcctgctc catcgatttc tgctgattca tataaagatc taggaacatt
    70681 ttgtaatgta gctaagtaaa gtagcattgc tcctccagaa ctccatattt tcatcaaaat
    70741 caacgcaggt ttcgtccatt gtggatcaaa cagccaagct ggtccaggga tatggaacca
    70801 gcccagaaat gtgttgatca atcctgcaga tggagaaagc agctgcatcc ataagatgta
    70861 gactgctact cctgataaga ctgccggtaa atagaaagct gtacggaata cactgattcc
    70921 tttgattttt tgattgagta ctgtggctaa aaacacactg aaaatcgtcg tcagcggtac
    70981 attgaagatg acgaaataaa cggtgttgta taacgatttc caaaataaat catcgtgaac
    71041 gaacattctt ttgaaatttg ctagaccaat gaaattcatc ttggatgtca aattataatc
    71101 ggtgaaacta ccaataactg aaaaaagcat aggccctagc ataaatacca agaacccgat
    71161 aataaaaggc gagataaata aataggccca tcttgcttct tttttctttc ggatagataa
    71221 acgcttcaaa ttttcttgcc tcctctgtac ctagacagtc aaaaatggat tattgatttt
    71281 gcttgactaa gttttctact gctttttgtg catctgccaa tccttctttt ggtgattttg
    71341 ttcctaaaag aatctggtca atctgttcat tcactaatgt cgtgtaatcc ggagcatcta
    71401 aaggaactgg tgtgatcacc gtatttttaa agttttcgtc cgccatttga tagatcattt
    71461 ttcctttatc cgttaggttg tcattattca ctaaattctc attggctgtc ttgctcgcca
    71521 tgatatcaaa acttttttcg ccgaattttt cttgtacttc tggagaagaa agatatttga
    71581 tgaattcata agaggcctca ggatcttttg ctccgtatgg tacttccaag acgaatccgc
    71641 caccccacga ccaatggcct gaaccttctt ctttttctgg gagctgcatc acgccaaaat
    71701 caaaatcatc cggtgcattt tccatcaaac tagagtaata attgatattt tgggcacgca
    71761 tggctactaa tccggaaata aatggatcag atacaccaga cccaaattcg gcttctaatt
    71821 tattgatcgt atttttccca taataatctt gccagtcttg gatccactcc aaggcttcca
    71881 ctttattttt agtatcaatc ttgacttttt catctttgtc aaaccaacta gtcccgttat
    71941 ctgcgtttag cgcccataca tcagccccta aattccataa tggataaaaa ccgatgcgtg
    72001 taaattcttt tccttctttt ttatctagtt tacgtgctgt ttcttctaat tcatcccaag
    72061 ttgtcggtag atcttgttca ctgattccag cttctttaaa taacttttta ttataaaaaa
    72121 tgacttgtgt atctgtattg aatgggatcg cataaggatc accttcatat tctactgtat
    72181 cccaaagctg cggataaaaa tccttagaag tgtctttttc tacatatttg gagagattag
    72241 ttgcttgctg tgcttctgct ctttgggcaa cggaatttat gtcctgtaca ataacatcgg
    72301 gtgcatttcc agctgttatt gcagataaag atttagtcca gatgtcaccc catggctgat
    72361 acttataatt tacatggatc tcgttttgtg attgattgaa atcctcaatg atttcttcga
    72421 tagcttcttt tcgtgcaccg gatccccaaa aggaccagaa atcaatattt tttcttccat
    72481 cacttgtttt ttcagaagaa tttgctgcac ttgaactggc atcgcttgca ttacttgatc
    72541 cgcatcctcc taataaaaac aatgctgaac ttgccagcaa ccctgtaaac aataattttt
    72601 tcatatttta cctccaaatt ttaatgtaac cgatgccggt tttaatataa cgatatcatt
    72661 ttgttctgaa aataacaatt tataaggtat gattctaaaa aaattattaa tgataccaat
    72721 actttatata attcgcgagc gctttctttg aattttttaa tctttcgtag cagaatgaga
    72781 atgtattaaa aatagattag gaggaatttt gatgtttaga caccagaaag aattgcagtt
    72841 tgaagcaaaa ccagatcgtc cgaatccatt aatcgcgaaa tatctgcagg agctgatcgg
    72901 cggccaatat ggcgagatga gtgtagctat gcagtacctg ttccaaggct ggagctgccg
    72961 aggagaagaa aaatataaag atatgctgat ggacattgca acagaagaaa tcggccacgt
    73021 ggaaatgttg gcgacaatgg ttgctcgttt attagagggt gcgcctgttg aagatcaaga
    73081 agcagcgatg caaaaagatc caacaatcgg tgccattatc tctggaatga atccacagca
    73141 cgcgatcgta gctggcttag gacctcgtcc tgctgacagc gtgggcaatc catggagcgg
    73201 tgcctatatc attgcgagtg gcaacttgtt agcagacttt agagctaatt taaatgccga
    73261 atcacaagga agacttcaag tagcacgtat ttacgaaatg atcgatgatc gtggcgtaaa
    73321 agatatgctg tctgttctcc ttgcaagaga tagctatcat caaaatctat gggaatgtgc
    73381 agtgaaagaa ttagaagaaa aagaaggttc aatcttagtc ccaagtactt tcccgcgtga
    73441 caaagaacga aaagacattg cttatgactt ctataacttc tcagagggag accaaagtag
    73501 tgaaggttct tgggctagtg gcaaagcact ggatggcgaa ggcgaatatc aatggttgaa
    73561 agaacctaag atcgaaggcg ctgcaccaaa attagaacca gtaacaccaa aaatgtatgg
    73621 gacacctcca ttcaagaaat aaatatctac ccgtagaaac acccgttttt tgttccacac
    73681 gctttgtgag caaaactgac taaagtcatt aatcataacc acccttcaaa agggtggttt
    73741 tctctagagc tataagctca aatcaccggc cagcgcctaa agacgctggc tttcatattt
    73801 tatgttcaag ccatattgcc tttgccagtt ttgcccacct cttaaaaggt ttatgtacta
    73861 ctccttagcc cttaaaagga tcgtcttact ctcgtacact cagcttatct aacgcactat
    73921 catgtttttc ttgttcttga atgtactttt tgatggtcgc ttcattttgt cctacttttg
    73981 tcacatagta tccttccacc caaaagtgtc gatacccaaa tttatatttt agatttgcac
    74041 aatctcttga tgatctcctg aatattggct cgatattgat tataaattat ttttcttcta
    74101 tactttggtg tgaatacaat gtggtattta cacatctact ttgtacgggc taaactattt
    74161 ccctttattg ctccacccgc atagcaagtg gttttgtatt tcaatcgctc ggcgcgctca
    74221 attaggtcta aagacaataa atctaaaaac ccgctgcttc actgacagaa acaacgggtt
    74281 ttcagaaaaa aatgaaatga aaaagatctc ttacggcaat ctattttatt tttttgattt
    74341 tttataaatg gaaaatgctt caagaagtcc aagaaataaa gccgtataaa aacaagaacc
    74401 tatgaaatct ttatttatta gatattcaac agaaatcccg ataacactag ccaacaatat
    74461 atttatcaga agtgtaaaat aaggatgctt tttatagaat agaactagtg ttgttttcat
    74521 agactctcct ttcttcatat ttccaattaa tcacaaattc acggcattac tagaaaaatt
    74581 aaaggggcgc agaagtggaa aaatactctt cgactttccc tacaaaccag gccatcttgt
    74641 gtttaataac tataccaaat ctaaggtacc tctaaatcta aattccattt gtggcggtga
    74701 cctccaattt ttaactcttc tatctcccat ccagtataca taaccttgat acttcgacca
    74761 cttatatatc gaacacacaa atacctatcc attgcaggag tactacctaa cttagttgct
    74821 acttgcatct aaataacagc tgaaaagata ggacttactc ttagtaaagt atctgaacta
    74881 ttaattttta aactatcatt tttatcctca actacatgca catctgttgc aacttcactt
    74941 tctgtctcat ccagataaat gattaaggaa tcgggaattg caatatcttc agctgacgct
    75001 ggaatagttg agctaaatta gtcatcatat ctttattata aaataaccaa cagcaaaaaa
    75061 tacaatgaaa aacaaacttg gaactaatgt atcattaata aatgttgaaa aattcagcaa
    75121 ctcattactg tatgatttta gcagcccaac caacatatac cctataaaag ctaataagat
    75181 ggttaggaat cctttagaat ttttactcat tcatagacac ttccttaaat aacttttatt
    75241 atagaaggta ttgtaaataa taatattgac aaaaagtgac tcaaaataaa aaaaaactta
    75301 cattatactg gaatgaactg tattgatagt gtacctaaaa gctctactga cataagatcg
    75361 tgtaatcggt aaagtaattt tattaattat acgggatgta atcaattaga gaataaacta
    75421 atcataaaag gtacttttac attcataatt gtcgctttga gattctactt tggttcacta
    75481 tctgacccaa ttgcacattt tcgatcatta caagtattgg tgtcgttaga acaactaaat
    75541 aaaaactagc ggtagatttt tcagaatcta tgctaatttc tgtatggatg ttccagtgat
    75601 ggcaaatttc tcttttcatt gtttttcttg tcgcatgata tgcctttttg tgttattcag
    75661 ttaaactata gaaattcttt cctagacaga tcttgatccc aaattttacg tttttgagca
    75721 tcgatatagt ttaaaatgac attactcata tctaaagagt ttagattttt taggactaaa
    75781 actgtcagtt gttctttttc ttctttctgt taaagtattg tcgcgacttt tcgtatacgt
    75841 taagatatgt cgtgaaaaaa caagttttgt gacacaaaaa aacgaatgac ttgaggaaat
    75901 cacctcaatc attcgtttaa aatgctatat attctttagt ttaagatacg gaaattaatg
    75961 ccatcgacca cactagtaga atgaacgaca tttacttggc ctttttttaa tttcgttatg
    76021 tttagcatat aaaaatatta tagagtttac ttacaatgct taaaacatat actgtataat
    76081 ctgatcaatt ttagccatgt cttgcaatgg taagttttct atttttttga gttttcgttc
    76141 cttaaaatca agagatttta attgtgtaat aattacttgt ccttttatat ctagctcttc
    76201 aggtaatgag taacgtgtcg gtaaattctt tatagtggaa gtaattggac atatgaccga
    76261 aaacattgtt ttacggttaa attcataacg agagacgact agtcctggtc gtcttttttg
    76321 aatttctttt cctacggagg gatcaaaatc aatccataca atatcacctt ttttaggaat
    76381 ataaattctt tcttctgaca ctataaaatt tctctccctt caggagttaa atcttcccat
    76441 tcgtctttct cataatactc ggcctcttcc ccaccactaa atggatcttc aatttttgga
    76501 actaacgtaa ttgttccatc atcagaatac acaacgatat attcttggtt ttctgaaggt
    76561 ttctttccgt tatcagaagg taaagttacc actacagaac ttccttgtaa tctagatttt
    76621 gtaacaagca ttatcatcac tcccttaata aaagtatact atataacact aagtaacgca
    76681 aaattcccct ttgtaaacta tctagaaaat tgttttgttt aaagtatatc ttattggata
    76741 taaatagaaa taaattgtag ccagttcatt ttttctttaa ctaaaaaaat aatccaagaa
    76801 acattgaacc tatggatcca aaagctaccc aaatactata gctaaccccc cgctaccttc
    76861 aattttgcag ataaaacgct ttgggagaaa atttcaaaga caacaggcca tcctatcatg
    76921 cccgattata aacaaaaagc tggctattcc ttttgctctg acaaatttca attgggaaag
    76981 ttcacgaaac tagcaggtga agaagtttca actgttcgga tcaaagaatg cccgcttcaa
    77041 atagaaacat tggttcaacg aatttcaact agacaagact ttgctattgt agaacgtgag
    77101 atcgtagcta tttttgtaga agaagggatt ttacatgatc caactcatat caatgtggat
    77161 aaatggcaac ctcttatcta taaattcaga gaatatacaa ctgccaacca gtcgttaact
    77221 ttgaatttta gattccaaga attcaaagag tcataatgat aaacatcgtt aggtataaat
    77281 aaaaaagact cgcagcacga gtaaaaaaca aatagaagct atacattaga aaggtcgact
    77341 gtgaccctat agatgcagta tatgcagctt atgagcattt cttctgttct ctttgttttt
    77401 gggatctgtg ctgaagtctt tttcgttttt tgccgctctt tctttgaaaa atcgattatg
    77461 ttataccttc tccattacta attcaggcat ctgctgagta atgatttttc gcgcaaaaga
    77521 aatatctgtt acccaaggtt cgatttgttc ttcagtcaag acaagcggca ttcggtcatg
    77581 gattggtgcg actgtgcggt taggttcagt agtcattatg attgattctg ccattttttc
    77641 atcctgatgg ctacgataaa aaccgccaat atacactatt ttttccttat ttgaaaacat
    77701 aaatttgtct ttttcttcat tccactcatt gggaaaacac aacgattttg caaaaatggt
    77761 tgatgaaagg tctttttttc ttctactgtc tctgcacggg cattaatcat caattgtcct
    77821 tttttaaatc cggtaaatcc ccacttcatg atttccggag tgaggatgtt ttcttcctct
    77881 tttcttaacg tcacaacaag atttgacgga aaaacttctc cagctgctaa ttctgctgcc
    77941 tgcttcggtt gtttcgtctg ggcttctcga taataattct gaaggagctc tgactctaga
    78001 tcaaaaaaat aacgaccaca catcctaatc cctcccaatc tttttttcta tcatacactg
    78061 caacaagaag ttcgcaccaa caaaacactt tcaatttttg tagaactaaa aaagttgtga
    78121 caagtgacaa actctccagt gaatggtatt ctcctgccaa ctcctcggtc acaagtcaca
    78181 atattcaaca aacatgagaa gctgcttttt gaaattgttc cttgtgactc ggagtgaaac
    78241 ggcaggctta cgacctctgg gtaaacggtg ttcaaaagcc agtttctcgg tattaagcca
    78301 aatttatgca aaaatgtaga aagctatttt cacaaaattt ttcttaatac tcgaaactaa
    78361 gcgacttttt cacaacctct tccttaaacg gtgttcaaaa gcttgcatct gcggtaataa
    78421 gcccaaccaa acgaaaaata tgagcagcta tttttatttg gctgttctta ttacttgatg
    78481 cagggcagct ttttcacaac ctctccacta aacgatgttc aatcagctaa ccttcggtat
    78541 tagctcaaaa aacggcaaaa tatgaggaac tattttgccg tttgtttctc taatactcag
    78601 gtcaaagcgc tgatttcaca acctctaata cacggtgttc cagaagtagc ttcttcgaaa
    78661 aataagccga aatttcacaa aaatttgaga agcaattttc gtaaattcct tcttatttct
    78721 tgaagctgac cacttctgtc acaacctcta attattaaag aaccttttgc gaagttaaca
    78781 atctttcttt gaccaattga aaattctgcc taagtagtga tagatcctgt gtgactttca
    78841 acaataagat acttccctgg atttcagcaa tcaacgcttt ggcttgacgg tctgcttctt
    78901 catcggacag tttttcttca gaaagtgcca ggatattttg tttcgtatac ttgacccatt
    78961 gattgactaa ttctagtagc aacagacggt attcttcatc cactgtactc aactcaataa
    79021 tcaaattacc tacaggacag ccatgataag tgatctgtgt ctcatgatca gcgaaaatcc
    79081 agtccaacat ttcttctaat gcttcttctg gctgttttcc agcatttaag atgtcttcga
    79141 acaattctgt ctgccatacg tccatatgcg catggatcac cgctagacaa acttcttttt
    79201 ttgaagaaaa gtaataataa aattgacctt ttcctgtatc agaagctgct agaatatctc
    79261 ggattgacgt ttcatgatag ccttttttat aaataagatc tttggtcgct tccaagatct
    79321 tttcctttgt tttcaatgat attctccttt ttcatttctc atagtcctat attatacagt
    79381 aaattcatca ttttttcttc ttaatcgttt aaaaaagact gtgccaaatt atctgacaca
    79441 gccctcacta taaaactgtt ctcatatagc tagatgttca ttgattcaag aactgcgagg
    79501 acaaaagcaa ttcctatctt atgatagttg ctctaatact tcctctgttg tcatcacttg
    79561 atctgcaata aagccaaagt tcgtcaacgc tgcatccatt gcttcttggc caggagcacc
    79621 aattgcatct gtcgctacca caacattgaa tccactctct accaattcac gcatatggga
    79681 atcgctacac aagtttccgt tcattccacc aagaattact gtgtcgattc cattttttct
    79741 caattggagc gccaaatcat tgctttctgg tccaaagatt ttatgaggag agctgatgat
    79801 cgtattttca tccaaataag gtttcaattc ttcgataaaa tcggctcctg aaccttcttc
    79861 cactgattca tattgacttt ttctagcaaa catctgctgc tcaagcatca tatgttctcc
    79921 tgcaccgcca aattgccatt tatggtcatg tgggtaaaaa taatgaggag aaataaagag
    79981 tttgtatcct ttttcttttg cttgttttac catttcaatc atattttcga tcgtattgta
    80041 tttttctaag atatcttttg tcaaaccaaa gccaccgcct gctggtttca agaactcgac
    80101 ttgcgggtca gtgagaacta ctgctgtatt tttattattg aacatggtgg attctccatt
    80161 cgttatttat tttaatacat catttagagc ttcactcatt gtcggatgag aatagatttg
    80221 atctctcaat aacgtataag gaagttttcc attcatagct agcgaaatca agttgatgac
    80281 ttcatgagaa tcttccgcat agatacttgc ccctagaatc aagtcagttt cagggtcgac
    80341 taaaactttg aatacacctt taggatcttc taatacttgt gctttaggga caccgcttgt
    80401 catatacttg aataatttgt aattgacgcc ttgtgctttg gcttgttttt ctgttaaacc
    80461 tacattggat aaagtcggag tgataaatac actgtaaggc acagctttcc ggttattcgt
    80521 tgttcgttta ttctcgccct tcaactgatc cataatgatt cgataatcat ctagagagat
    80581 ataagtgaac tgcaatccgc ctttgacgtc tccaatcgcc caaatgttgt ctgcatctgt
    80641 acgaaggtat tcatccacag cgattgctcc gcgatctgtt agtttaacat ctgtattttc
    80701 taatccaagt gatgctgtac ttggttttct tccagttgca gccaaaactt ttgacgcttg
    80761 gattgttact tcttggccat cttctgtaaa ggtgacggca gctgttgatt cttggtctgc
    80821 tacttgatct acagatacac ctagatggaa ttcgattccc gcatttgtca tgtcttctaa
    80881 aatcatttgc gcgatatctt catcttcacg tggaagaaat tcagaatggg catcaagaac
    80941 gacaacttta gatccgtatt cattgaacat tgatgcaaat tccaagccaa tatatccagc
    81001 cccgatgatc actaattttt ccggtaattg ttcctgatcc atcgcttgcg tagaatcaat
    81061 caagtagcga cttgtattca atcctttgat tggtaaaatg attggttcag aaccagtatt
    81121 gatgaaaatc cgttcgcctt caacaatcac tttttcacca ttattcgtca cttcgatttg
    81181 atggttagaa agaaaacgtg ctgtaccgtc catcactgtc ccagttgcct catcgctgat
    81241 catatgataa tttttggcgc gaagcatgcc cgtcaatttt tctttccgag caacagcctc
    81301 tgtaaagtcg attcctcttt ctccattgaa aatcaatgat ttagaaggaa tacagccgat
    81361 gttgatacat gttccgccat acatacgtgt tgacttttca acgactaaaa ccgattcacc
    81421 ttttgaagct aacgccttcg ctaaagtctt accgcccttt ccaaaaccga tcacaatatt
    81481 ttgatatttt tccatcattt ttccctcgct tcttttttac ctaccgattg gtacaaaaat
    81541 atgataaccg ataattgtct attctccaaa tcatctgctt tatttgtcaa aaaaaaccag
    81601 acaaaaagcg gtcctttcac gtttttagtc tggttcgatt tcctttattc ttctaaacaa
    81661 tcgttacttc tacatcgata tttcctctag ttgctttgga gtaagggcag aattcatgcg
    81721 catcttctgc aattttttgg gcttcttctt cgctgatgcc atcgatatgc acttcgaata
    81781 ctacaccgat ctgatagccg ccatcatcta aattataaag agagacacgt gcttttactg
    81841 tggactctgc tgtcattcct gcttctttga tcatatgttg taccgcccca ttgaaacaag
    81901 aagcataacc tgctgcaaat aattgttctg gatttgttcc ttctgcatgg attcctggag
    81961 gagtgatttt catatgcatc gagccatttg gttcctcgac ttctccattg cgcccgccat
    82021 ggttgatcat tgctgtttcg tatgcttttt tcattgtact gctcctttcg attgaccatt
    82081 tgctacttgg ctataattat agtgtatgac aagtaaggcg ctttctacaa aaattctgct
    82141 tattcgaata ccagaatgcc gtcttctact atttttccaa aaaacaaaaa aatactactc
    82201 gtgaacaaca gcgtcatatt tgttccaaaa taaatagcaa tcttttctac ataatctttt
    82261 atatgattga ttttaagata catatatacc agaaagttga ccccataaac caatactgtt
    82321 aaaaaaataa ccatattcgt taccattttt tcctcctttt gctggtctcc ctaccagcac
    82381 tcgatttaac cataccactt tttttgccgt ccaagcaact agcctttcaa aaagactggt
    82441 ttattctgct gttaatgatt caagatcaga aaaatgtccg aataattttg ctaattttac
    82501 taacgccaac ttgttctttc cgaattcatc attttctatc tgtaatacta gtaacggctc
    82561 atgtaagctt aaacggatca aaaaccagcc gtttccgtat ggctcttcta gatcatatcg
    82621 aataccttct tcattttccg ggtcgaagtt catccctttt tcttcttcca acagtcgctt
    82681 catttcttct aatatcttgt ttccttgttc gcgtggttca tcgctgaaca attttaatcg
    82741 gatttcttgt acttctacgg gctgtttcaa ctctttgatt tgttcatcta atgtgatacc
    82801 ttttcttttt aattctggca aaagcatcag gatctttgcg atgacatatg caccatcatc
    82861 cagaaaatag ttttccttga atgcagcgtg tccgcttgtt tcgatggcta gctgtgtatc
    82921 tttcccaaga cggttaagtt ctaatgcttt attgattaca tttcgatagc cggaaatata
    82981 acgaacttgg atgcctcctt tttcttcaat gaatctttgt agatgagaag aagtagggga
    83041 attcgtcacg attcttgttc ctggatgctc ttttaatacg attgtactta atactgcgat
    83101 caaattattt cgattgatca ctgttccaga agcactgaca actgcagaac gatccacatc
    83161 tgtatcgaaa atgatcccaa gatctgcttc atttgctaaa acagcctgct tgatactttc
    83221 catcgcttct ttattatcag gatttgggat atgattagga aatcggccat ctggttccaa
    83281 aaattgggaa cctgttgaat ccgcacctaa gctattcaat actttttcag caaagaatcc
    83341 accagcacca tttccggcat caacaatgat tttccaacca tttagtggtt tgctttctag
    83401 tgttccaatc ccctttttaa tttttgtgac taaatcttgc gcataaggtg tcaaaaggtc
    83461 tgctttttct acgcttccag tttgttcgct ttttattttt tgctgctgtg ataggataaa
    83521 agcaatatct tctttttctg ctcctccttc tgaggtaaag aattttattc cattataata
    83581 atagggaaga tggctagcag tcagcataac cgcagcatcg cacgagaact gttcaaattg
    83641 agtggacata aacatagcag gcgtagtagc taattcgaaa tcgatgacat gtatcccttg
    83701 ttctttcaga ctttggatca acgcctcttt cagtgctggt ccgcttatcc tactgtcatg
    83761 accaatccca atcgtccatt ttttatttgg atcggttgat ttcttctttt tctttatcca
    83821 gtttgctagt ccccagccga tcttttttac catgtctgtc gtcaagttta cttcatatcc
    83881 ttcaactggt aatgcgattc ctcgaatatc cgatccattt tgcagcgctt tcatatcttt
    83941 catataaaag tcctcctcat ttattccctc attttttcca gcttttctgc aaatcgctgt
    84001 gcttcttctt ctgagcggca aataataatg aatgtatcta caccggccat cgttccgaca
    84061 acttcagggt aagccacttc atctagccaa ttcgttacca catcggcacc atttcgttca
    84121 gtcaatacga taaccatgaa ctgaacagac tggatacgca aaacctcgcg tctaattgct
    84181 gtacgcaaac gttcttcatt taaagaaaca gatggctggt taaataatgt atagcgtact
    84241 attttgtttt cattttgact ttttactaac ttcatttctc gaatgtctcg agaaatcgtt
    84301 gcttgagtca catcggcgcc tgcttcatgc agccgcgcaa gcagctcttc ctgtgtccca
    84361 ataggttgtt ctgtaatgat ctggcggatc agtgcttgtc gctgtttctt tttcatatta
    84421 gacacctctc aatgttgatt atagcaaaag ataagtaata tttcttcata ttttggtatt
    84481 ttttactttt attttttgtt ttcattcagg ttgctaacct ttttctattt taacacgcaa
    84541 aatcgtcttc attttttcag gtgctgattt tcttggatcg ctgatgtaaa tctctttgtg
    84601 ttctttagaa gctctttcat agccttcttt tgcgatgaat gcttctaatt tctcaaacgt
    84661 tgctggttct tcggcatagg gcccgacgtg taagatttgg gcacaaagac cttcttccat
    84721 ctttttgaat actacttgtt ctttcaagtc ttccggaagt ttgctagaac gctgaatggc
    84781 ttcttgtgct atcgcttctg taacaaagtc aggctgtcgg atcatcaatt gataagaaaa
    84841 atgttctttt ttcatcactg gttcatgcaa atacttttct tgcagtcccc attgtccttc
    84901 cagtggatag acagtataca tctgataatc aggaatcagc caattttttt taggcgacat
    84961 gcgtattgca tagctgactg catatagaca ggctactctt cgtttaaagt cttcctgatt
    85021 cgggtcgccg atccctctga tgctaaagaa tgatttttta ggaacctcta gtatttgcgg
    85081 gctttttttc atactatagc tcttgtcttt acgccattca attttttcca tttttcttcc
    85141 tccgcgaaat tccatttagt tatttattat catacctctt tttgagtgac ttggctaatc
    85201 gtgttgacac tatttttcag tttgtgctag aataagtgaa gtaaataaat cgtacagata
    85261 acacgtttcg gcgtgtcgag agagaggcgg tttctatttt tataatagaa atcactctct
    85321 ttttttacga aattttttag aggtgatgta aatgacaaaa caaaaacagc tgcttttagt
    85381 acctgcagta attgcaacag ggatgatgtc ttttgcgggc gtattgatcg agacggccat
    85441 gaatgtaact ttcccaactc ttatcagaca gtttgattta acgactgcac aagtccaatg
    85501 ggtaacaacg atttatcttt tgatgatttc gatcattgtt ccgctgtcta cttatttgaa
    85561 tcgcaatttt agtctcaaaa aactcttttt agcttcaaat ctgcttttct tggcaggtat
    85621 aatgatcgat ttcttctctc ctaccttcat ggtcctattg tttggtcgat tgctccaagg
    85681 tgcagcgaca ggtatcgctc ttccgttgat gttccatatt atcttgacat ttgcccccct
    85741 caatcgacga ggcgcgatga tgggtgtcgg tactttgaca acggccattg ctccagcaat
    85801 tggccccact tatggaggca ttatgacttc acattttaca tggaatcata tcttcctgtt
    85861 tcttgtgccc gttttgattc tttctttgat tatcggctgg tttgctattc ccgagatggc
    85921 agtacaaaaa agtggttatt tggattggat aagcgtttta ggaatttgtc ttttgtttag
    85981 tggaagtcta acatttttga gtacgttggg aacagtttcc agctggattg ctttaatcat
    86041 cggcggtatt ggctggttcc ttttttacta tcgaagtaaa aaagtggagc atccactgat
    86101 ccgactgtct attctttcaa ataaaacatt ccgcttgttt ttgattggct tcttagttta
    86161 tcagttttta ttacttggtg tatcttttgt cttgccgaat ttccttcaga tcgttcaagg
    86221 aagtagtcct tttgtcgctg gattagcgat gcttcccggc gcagcggttg gtgctttgct
    86281 ttctcctttt tccgggaaaa tgctggatca atatggtccg aagaagccaa tttttgctgg
    86341 gctgattctt tctttgattg gttggctagc attattccta ctcataggac acgcttcagt
    86401 gggtgtattg attgcttgtc atgtgtttta tatgatcggt atcggattat cttacagcaa
    86461 tatgatgacc accggaatga atgcactgaa tgaagaacta caaggagacg ggaacgcaat
    86521 gttcaatacc ttgcagcagt tttctggcgc tgtggctact tcattagtag cggtcattat
    86581 caattacgtc cagcatcata cttcccataa ctatgaagtg tctactacat taggatcaaa
    86641 agcagcatta ggcgtcttgt tgctgttgct tctcgtaagc tttgctcgat tcgcctatta
    86701 tctgttcttt gctaaaaaag cgtagattcc atatacggca ggtgttgcat ctgccgtttt
    86761 tttgtgtgaa aatggttgtt tgtaaaagga ggctttttta tggaaaaaat tgccattatc
    86821 ggtggcggga tcattggtat gaccctagcc agttacttag atacatcaaa attcaatgtt
    86881 gctttatttg atgaagggac aggacaggca actaaagcta gcgctgggat tatctcccct
    86941 tggttgtcga aacgcagaaa caaacaatgg tatcgtctgg ctaaagacgg cgctgctttt
    87001 ttccctaaac ttataaaaga tttccaactt gatcaaacga tttacgcaca atcagggaca
    87061 cttttgcttc gacctgaaaa agatttagct gaattggctg ttcttgccga gaaacgaaaa
    87121 gaagaagcgc cagaaattgg aaacatcgaa tggctttcac ctgaacagac atctcaagca
    87181 cttccgttat tgaaaccagc agtttcactg cgtatcagtg gtggtggtcg tctggatgga
    87241 aaagcatatt tagaacatct tggtcagcgt ttagcacaaa aacaaatgga gcagatccag
    87301 gcaaaagtca ctttgcataa gaagagcgat tcttggctca tcaagggacc gtttggagaa
    87361 tacacagctg atcgtgtaat tttgacacct ggcccggcac ttaagccttt attacaagaa
    87421 ttaggctatg ctgcagatat acgtccgcaa aaagggcagc tcttagcatt tcagacatct
    87481 tataagatga gtcaagactg gcctgttgct atgcttgacg gagaagctga tttcattcct
    87541 ttcatggatg gaaagatcct tttaggtgct acccatgaaa acgatcaagg ctgggatttg
    87601 gctcctacta gcgaagctta taagggattg actaagagta cagaacagtt cttgactgat
    87661 ccagatcaga taaaaaactg gccatacgag ttccgtgtag gtacccgtgc ttatacgtca
    87721 gatttttccc catttttcgg cgtactgcca gatgatccaa gcttactggc tgctagcggt
    87781 ctaggctctt ctggcttgac cacaggtcct tatatcggct atctattagc caacttctta
    87841 aatactggtc attggcctac ggaagattat caaaaggaca tctccaccta tattacgaaa
    87901 aatccatcat agaaaaacag ctttttcaag taaggatccc gagcgatatt gcgcatggat
    87961 tacttcttga aaaagctgtt attttagttc aatttctgaa tcaaattctc caaactttct
    88021 tttgcttcat ctggcaagag atcttttcct atctgagctt caatgaatcg taaacgaata
    88081 tcaagtcgtt gtttcaccag atttttatag gacgtatcct caaaagaaac aggaaaatct
    88141 ggtataggta aatagtggat gtcttcaaat ggaccaaacg acttgaattc tgccgtttgt
    88201 tgcacgattc tttcaacgat tgacaatgtc gtttcaggtt tgattttttt atcatcgaaa
    88261 tatccagtat tcaggacata gcaggctgtt tgctgtttca aaaacaactc tcgaaaagct
    88321 tgatagtctt ccctaagagg atagacacgg aaaggattag caaatggttc aatgactagc
    88381 tcatctagct gtctttttgt agtgatattt tccgcgtctg atcgttttgt tgctaatgtt
    88441 gcaccaaaag acgctgctaa aactgggtca ttgatcttga taattggcgg aagcgaatca
    88501 tctttcatga tccaaaaaac agcatcgatc ttttcgctaa gatgatcgac tcggtcgggt
    88561 gtcgcataac gtgatttgac tgtccgccca tttccgtttc gtatatctcc tgttactagg
    88621 actttttctc ctttacttgt acatgtcacg cccacattct gacaagtaag gaaagaagaa
    88681 atggccggat catcagacgg atagtcttgt gttttatcaa agtaagaagg ttccaaggca
    88741 gtagcaaaac cattttttcg agaaataacg aaagcatcgt catgcaagat cgaaacagag
    88801 tgaccttccg tatgttttgc taaggtaatc gttgattttc cagaaccgga caacccaaat
    88861 acagccatcg tataggtctg gtcattacta gcatattgtt tcatcccacc gtggcaggca
    88921 ataaagccat tgcgatttcc caatgcccaa gcaagcgtca aagtcgcttt ttttaattct
    88981 ccaaagtaac gtaatcctag cacaaccgct gtattatgga gagcatcaaa caaaatgagt
    89041 ccatttggaa atgtttcatg tgtccattcg ggatcacaaa agatataaag atctccctca
    89101 tcaaaggaaa cagacttttg ataagtctct aagatcttcg aattcgctgg ctgaaaattc
    89161 agcaaataag aatacaaatt gttctcaaat ccttctggaa tcagcaaatg actttgcaca
    89221 gaaaattctt cagataggcc aacgattact tttgtatggt aaaactggcg cttgcgactt
    89281 tgatacacag cttctcttaa aattttctcg tatttgcttt gttccttgtc taagtcctca
    89341 aagatccgcc gagcacttgc tgttcttccc acaatgcttc catcattgaa tactagtgtc
    89401 ctaacatcag ctggtaaatc tagttcttca gcatgtgaga ttgttaaatc tgtgatgatc
    89461 gttcctggac tcccttttgc tagttgataa gctgtcttcc tatcaaaaac ttcatgaaca
    89521 ttattaccgt aaaatgtcgt ttctacaatc gatcgaatac tggataacag tggatttcca
    89581 cttgtgattt cgtttaattc gagactctct tttgtactca tggctcctcc tcattcccta
    89641 aacaaaaaaa cgttttcttt attatacatt attcgagttt ttatttgtac tgctgcgctg
    89701 tgggaagcaa acgagttatt tttcacacaa aaaaaccgag aacttgaata aacaagtttc
    89761 tcggtttcat cattttcctt ttatcggctt agtaccagcc gtttgctaac cagaatgttt
    89821 tagcagcatc ccatgaacca taacgagatg ttacatattg ttctgctaca cgttcttgat
    89881 tggcagctga atagtcgccg tttaagtatg aagcatctaa ttgataacgg ccgatgtaac
    89941 gtccgttagt agctgtgtat gaaccgcctg attctttttg tgcgatccat tcttttgcag
    90001 agcttgaagt tggcgctgtt gcagcagctg gggcagcagg agctacttca actgtttcaa
    90061 caggtgcaac gtatgtatgt tcttgcgttg ctgtttcagt tgtagatgct gtattttctg
    90121 ttgttttgtt ttctgttgtt gctgaagaat catttgaagt tgggattgtt aattgttcac
    90181 caacataaat gcggttgatg tttgcgatcg aatttttttc agcaattgca tcgatcattg
    90241 agttgtctcc tgcaaatttt tgtgagatct tagataatga atcacctgat tttactgtat
    90301 aaacttcatc agcgtgagca tttgtagttc ctacaaacat tgcagtagca ccagcagcaa
    90361 aagttgtacc taaaacaatt ttcttaaatg aattcatatt aaactccttt ttttctccgt
    90421 tttttattct ttcgacgcta ttaactttat catttagaaa tatttcatag gtaaaagaaa
    90481 catgacattt aatgacaaaa taacgaatta tttaatattt gtaacattta aacaaatatt
    90541 tttttgatac aaaaccataa aagccttgtt gtataagcaa agtaatcgtt tttctatgtt
    90601 ttttttattt ttgaatgaaa aacgcagatt ctgtaacatt cactgcaata atccataaaa
    90661 aaaagcaaaa aaatttttga tttttatcaa attctcttaa aaaaatgtaa aaaatacaaa
    90721 aaaaccagta attgttacaa caattactgg acaaaaactt tgaataatgt taactatttt
    90781 tttattttaa ctttctccgc aataatttct gggcatgttc caattcgttt ataacgactt
    90841 cttctgtttc tttagctaat atttcatcta atacatcaag ccatttttcc ggttcttttg
    90901 ttcctagacg tccaatagcc caagctgctg ttcctctgat gacagggcgg acatctgtta
    90961 aacattctga aatctcaggc aatgccgttc gatcacctag attagctaaa gcaatcaatg
    91021 cgtttctctg caaaggtttc ttcccacgcc atgaaccagc taaatgccca aattgctgtt
    91081 tgaagtcttt attagacatc gaaagcattg gctttaattt tggatatatt tcgtctactt
    91141 ttggttccat ctcttcatga aaatgaaaat cttttccttg attgtaaggg cagactaact
    91201 ggcagatatc acatccataa atgacatttc gcattttttt acgatattct tccggcatca
    91261 tcccttttgt ctgagtttga taagacaaac atcgctgggc attcattctt ccgtcaccaa
    91321 gcaatgcttt tgtcggacaa gcagtcacgc agcgcataca gtcaccgcaa ccaaattctc
    91381 ctggtttatc aggctcaaat acaatattag taacgatctc accaagatag acaaatgaac
    91441 cgaactcttc agtgatcaac aatccgtttc gtccaataaa tcctaaacca gctcgctgtg
    91501 ctacagcgac atcgatcagt tctccagtat ctacttgcgg agctagacgc cattcctctt
    91561 ctttttgcca tttttctgct cttgtttgga tgaattcgat caatcggttc aaacggtctc
    91621 tgagtatatc atggtaatcg atcccccaag aagcacgagc aaactgcccg cgtttttcat
    91681 ccctaggcac ttcttcatgg atcctagtag gatacgcaag tgcaatggaa atgatcgatt
    91741 tcggctgatc aaatgtcatt tctggataaa gacgctcatc gatatttgga tgttcaaagc
    91801 cagaagtatg gccagctgct ttttgttctt ccaacgattc ttttaatgaa tcaaaaggtt
    91861 ccgccgtggt gaacccgatt ttgtcaattc ctaatcgttt gctttcttgt atgatttctt
    91921 cttttaatgt catggtcttc ctcgcttgct gttaacggct gtataaccca taatatagtt
    91981 tttctttttt cagctggaca aactggatct gctgatcggc attcttcttt tcttccatcc
    92041 atttttttct tgcagcaaat acttcccaat aatttgttga aattaatttt cttttgttat
    92101 ctaatgcatt aaaaaaattc aatgaaactg gttttgtact taacagttca tggagcctta
    92161 cctcttccca tggcgaaaac tcagacagat cgcgggaata caatacttct tcatagagat
    92221 ttttttgctg tgtgtacgtg aatgtttgcg ggattttccc aggcctagca atttctacta
    92281 gacgattata aaacatattc attaatttgc tgttggcaat aaattgactt ttataatagg
    92341 ccgactggat ctttttgatt actccttctg ctttgatgac tgaaaataat gcaggccatg
    92401 ctttgacggt tatttcgtcg ttttgtttaa ctaatacgcc aggtgtgaag ccgactggag
    92461 aaaggaacac aaaataaccg ataccggtat tttcatctaa aggctgaaat tcatcaaaca
    92521 accatttgcc tatgtacagc tcttcatctg gttctgttgt ctcattttga tttgctatga
    92581 ataatttagc taattctgct tcaagaaatt gaaggtcttg atccttgtcg gtattttcct
    92641 gctggctgat caatcgaaag acttcttctt taatcgtata tttatcttta cgtgtaaaat
    92701 tcatagccac accttccttc cttactctaa ctataacgga atttcttcaa aaaaggtatc
    92761 tgtacgacga aaaacagcat aatttttttt catatctctt ataaaaaatg caaggtctgc
    92821 tcctcaagct agaccttgca cttttcagct ttcttttgtt tgtgacaaac cttcatggat
    92881 cgtttcaata ttccatttca tcatctgata gtaagaatct ccttgttctc cttcttttgc
    92941 tatggaatca gtgaacagtt tatcatagat tttcaaaccc gtttcttttg ctacccgttc
    93001 catgcttctt gagtctacac tggtttccac gaataaaacc ggtacttctt ttgctcttat
    93061 ctgatcaatg atcgctttca tttgatcagg cgtaccttga ctttctgtat tgatctccca
    93121 tatataagct gctggcaaat catatgctcg tgaaaaatac ttgaatgccc cttcacttgt
    93181 tactaataat tttttgttct cttcgataga agcaaaactt tccttcgctt gtgtatctaa
    93241 ttcttttagt ttttccacat atgcttctgc atttttttat agagtgtcgc attttctgca
    93301 tctttttcag agaatatacg tgcgatttcc tccacatatt ttattccgtt agataggtct
    93361 agccaagcat ggggatctgc ttttgtatgt tcttcaccgc tagttaaata aagaggttct
    93421 acatttttgc taactgcaaa ataatctttt ccttcttctt ttttagccgt ttccatcaag
    93481 ttatcgaacc agctgttacc tgtttcaaga ttcaaaccgt tgtataaaat aacatctgca
    93541 tcgcttgcct ttttgatgtc ttctggtagt acttcatatt catgcggatc tgttccgact
    93601 ggtacgatac tgtggatatc tatttgatct gttccgacct cttttgccat gtccgccaag
    93661 atcgaattgg tagccacgac tgacaacttt tctttacttc cttcatccgc ttggtcagaa
    93721 gcctgctttc cgcaaccggc taataccaag aaactaactg ccaagattaa aaagagtgat
    93781 ttttttgttt tcatctatct gcttcctttc tgaaataaaa ttccttttgt tggagaaaat
    93841 aaaaaagcaa ggataaaaaa tgcggtacat gctaacacga tcgtagctcc tgatggccaa
    93901 ttgtaactat aactgaaaaa cacaccgaca actgcactta gcataccgat tcctgcagct
    93961 gtaatgatca ttttcagtaa atggttcgtt agcaagtaag ccgtggcggc tggtgtgatc
    94021 aacatggcaa tcaccaagat tgttcctact gtctgtaaac tgactacagc cactaatgtc
    94081 aaaaagaaca tcaaaagata atggatcagc gatgtgttca gcccataagc ttttgccatt
    94141 gtcggatcga atgatgtgat cttcaattct ttataaaaga aaaagacaaa tatcaagacg
    94201 attccactaa cgagtgctgt cagcaacaaa tcgctttccc taacagctaa gacattccca
    94261 aataaaatat gatacaaatc tgtcgcactc tgggcatatg aaatcaagat aatccctaat
    94321 gcaaaaaagg agctaaagac aattccaatc gctgtatcat ttttcaatcg gctccgctga
    94381 gtcacgaaac caatcactgc tgctgttagc atcccaaaag cagtggctcc aaagatgtaa
    94441 ctaaaaccaa acatataaga aatggctaca cctggaagaa ctgcgtgaga gatagcgtct
    94501 cccatcaaag acatccctcg taaaataata aaagaaccga tgactccaga agcaagtcct
    94561 acaagcatgg aagtgaccaa agcgtattgc aggaattgat aattcattaa tccatcaata
    94621 aaggattgga tcattttttc tctcctcctt ttactaaatg tctgatgatc tcaccatagg
    94681 ccaattgaag gttcttcgat gtaaagactt cttgtactgg accggaagcg atcagctgtt
    94741 tatttaaaag aataacctca tcgaaatatt cttctacttt atgaagatca tgatggacga
    94801 tcaaaatcgt ttttcctgaa ttcttcaatt cctgcaagat gtcaaagatc tttcgttcac
    94861 ttaacgcatc aatccctacg aatggttcat ctaaaaagat ccattctgct ccttgggcta
    94921 gagctcttgc aataaaaact ctctgaagct gtccacccga tagttcgctg atctgtcttt
    94981 tggcatattc ttccatccct acttttttca aagcttgtct tgcacgttct ttttcttttt
    95041 tcccaggtct ttgtccaatt cgtaaagatg gatatgttcc taaaagtaca acgcctaata
    95101 catcaattgg aaaggaaaga tccaattcac ttcgctgttc cacgtaggct atttttttac
    95161 ggactgagtt taccgactgt ccagaaaagg tgactttacc agtagtagct ggtatcaact
    95221 ctagcaaaga tttcataaat gttgattttc ctgcaccgtt tggtccgata ataccggtaa
    95281 ttttttgtgg atttatcgtc aagttgatag ttttcaaaac agttttccct tgataagcgg
    95341 ctgaaaggtc ttgaattaca atggccgtac gttccaaatc ttacactcct ttttaggttt
    95401 acctaacttt ttatttaaat atagtttaac taaaatggaa agcattttca agtagaatga
    95461 tgaaaaagtt tttttcgaat tttcctcgca ttttatgaaa attttctgta gaatcacatc
    95521 aagagttcaa taaggctaac ctaataatga aaaacatgtg ttgaaacgtt tgattatttt
    95581 ttcttgttga ctcaacaacg aaaggagttt ttgtatggaa gaagaaaagt taactcgaag
    95641 tcttagtgcc cgtcatatcc aaatgatcgc actaggtgga acgatcggtg tcggtctgtt
    95701 tatgggtgcc tcctcaacca tacgttggac agggccctca gtgatgggag cctatgcgat
    95761 tgcaggattc tttttgtatt tgattatgcg tgctttaggc gaaatgcttt acgttgatcc
    95821 ttcgactggt tcttttgcaa attacgcgag cgagtacatc catcctgtgg ctggctactt
    95881 gaccgcttgg agtaatattt ttcaatatat tgtcgtagga ataagtgaag tgattgctgt
    95941 aggatcttat atgaattatt ggtggcctga tttgccggca attattcccg gaatcattgt
    96001 cgtcttgttt cttatgctgg caaatcttat ttctgtcaag gcgtttggcg aattagaatt
    96061 ttggttttcg atcatcaaag tcataacgat cattttgatg atcattgcag gtcttggggt
    96121 aatcttattt ggatttggta atcatggtca ggcagtaggg atttcaaatc tttggaaaaa
    96181 tggtggattc ttcactggag gcgtcaaagg atttttcttt gcattatcga tcgttgttgc
    96241 ttcctatcaa ggaatcgaac tgatcggaat gactgctggt gaagcagaga atcctaaaaa
    96301 gacgatcatt gaagctgtcc agtccactat cggtcgaatc ttgatttttt atattggtgc
    96361 tatttttatc attgtgagta tctatccgtg gaatcaattg agtgagattg gttcaccttt
    96421 tgtacaaact ttttctaaag tcggcattac atttgctgca ggactgatta attttgtcgt
    96481 gattacagcg gcattatcag gttgcaattc agggattttc agcgcaagtc gtatggtcta
    96541 tacacttgcc ataaatggaa agatgtctaa aaaatttctg aaactatctc gtcacggtgc
    96601 gcctttttat cctgtcgtag caatctcagg tggaatctta attggtctga tcttaaatta
    96661 tcttctacca atgttcatca accagtcaga aaatattttc gttttcgtat acagctcaag
    96721 tattttgcct ggtatggttc cttgggtagt gattttgatc agcgagattc gcttcaaaaa
    96781 gaagcacgca gataaaatgc atgatcatcc ttttaaaatg ccactatctc cttatacgaa
    96841 ttatgtgaca cttgcttttt tagctatcgt attgattttc atgtttatca atcctgaaac
    96901 gagaatctca ttgattattg gactcgtttt cttgctttac atgacgatcc attactttgt
    96961 acgcgaaaaa agaaccggaa aataaaaaaa gaacgaagct tcaccttagt ggaagcttcg
    97021 ttctttttta ttgcttttat caattcaatt ttagcgtctc accgggagtc aggaaataat
    97081 tctccatgct catcccattc agcgacaaga tcgtttctac tggtacgcca gttcgttcgg
    97141 ctatttgatt tggaccttct ccttccaaaa ctacggttgt cgcagcctgt gaagtcgcgc
    97201 tgttggtatt agtttcagag gaatctgttg tgtcttgtgt tgttcgagct tgcatttcag
    97261 aagcttctac cgactctgct gtctcagaat cagaagatgt tgtgtcttgt gtgcttgttg
    97321 actctgcttg aagagaggcg ctagtctgca aataaatatc ggaaatctta gcgacatgat
    97381 tcgtataatt agccgataat tgattgatca aagtatctaa gtctacaccg tctttatttt
    97441 ctgctgcctg atacgctgca cgtaattttc tgatcccttc gtcggagatt gcttgaagct
    97501 cacgtgcttt ttggttagca actgctgata aaccagctat tccctcttga tttccctgaa
    97561 tttctgtctg gtattcttca atcaatgcag gcgtcttttc ttcgatcttt ttcgaataat
    97621 catttacgat tgcttgaagt tgctctggca aaccatttgc tgttttttct tcagaagttt
    97681 gtgtctcttt tgttttagtt gatgactcac ttgtttgttt cgtctctgtt ttctttgtcg
    97741 ttgtttccgt tatggtcgta cttttcgctt ctgacgaatt ttttccatga aaatatagac
    97801 ccgcaactcc tcctgctatg atcaaaaaca cggcaactgc tgccccaatc atgatcatcc
    97861 gcttacgagc tgcctgtttt tgctgtcttc ttcgggtcat ccgaacattt tctccccact
    97921 cattttcatc atacattttt ttcaccacca atttttatgt ataatagcgt tatcaaacgc
    97981 ttcatattct tattgtagca aataattgtc gctgtgcaca tttttatctt tgttatttat
    98041 aagaaaattt caccagttga gatgattcca agattgtccg tcgatttctc cttgcagctg
    98101 cattgttcgt tcgtctatct cagccatcag tttctttatt tcatataaga gcgcacggtc
    98161 ttgatattct gatttttcgc ttaattcatc taattgttgg atcagccaat catttgtcat
    98221 aatgaagttc ctttcatttc ttgcagtgta aaggtcaagt cttcgatctg ctcttttgcc
    98281 tcagtcagtg cttctacgat atatgcttgt ttttcagatt cttcttcctg cattttctga
    98341 ttttcctgta ctctttgaat aaaccagtca atccgctgag tcagcgatgg tttgccttcc
    98401 aatgagagat actgctgata agcaattagc ttctcccaac gtttttcctg ggataaatac
    98461 ataaattgtg ctaaaacgaa tggcggaaga taggtcatat ggaatttatt tgcgattcgc
    98521 tgatacggcc tcaaaaattc ggaaatcgta tattcttctt ttcctccagc ttggtattct
    98581 ttttccgcca cacctgttgt caatacgatt cctagttctt tcccttttaa tacatgtgct
    98641 gctcgttcca agacattatc ttgccaaatt tttaaatgag caggagaact ataccagtaa
    98701 aacggaaact ggaaaatgat ccgatcatgc tgggccaaga gctgtagttc agtctctata
    98761 tctatttttc cgtctggata acttgattcc aaatgatgcc aagtagctgg taaaccagca
    98821 gaagcttctt tgaaaaattg ctgatttaaa gattcttcga tcgttggatg gctaatgatg
    98881 ataagtgtac gcatcccttt tcctcctttt tagtcttcgc tttacagtgt agcataaccg
    98941 ccacaagttt cttttgccga tgcttgtcat tttaaccaga ctaatcaggt tgtccaagaa
    99001 actgtggttt gtttttccaa ctgttttttc aaggtatcca aagcaatatt cttaaaattt
    99061 ttgtttttca tacgtttacg atagttcgta gccgtttctc cggtactctt tttgaacatt
    99121 cggctaaata cgactagact attgaaccct acttgatagg caatactttc cacggattca
    99181 tccgtcagag aaagaagaaa cgcccctcga ttgatccgta ccccgatcaa atattccttg
    99241 atactggtac ccatatgatt tttgaatact cgcgacaaat ggctccgatt gaccgctaaa
    99301 tgctgggcga tttcctcaac agacaatttt tcagcataat gtgcctcgat gtatttgact
    99361 gtttcaacag ctaaagagga atgaaccttt tgtacaccac cgctgacctt tccgccatct
    99421 tttaaaagga ctgataaaaa acggtaggtt aatgctgtta actgtaattc attttccaag
    99481 gtttcttccg tatctttcat gcattctaaa ataatgtcga tatatttttg tatgtcagaa
    99541 gagaccatcg tgtattggtc ttctctgaaa agcgactgcc gaatgatttc ttctgcagca
    99601 ctcccaccaa atgaaagcca gcaatacatc cacggatctt ctccatctga taagtaaaac
    99661 gtcgagtctc ctggacgaat caagaacaga tcaccttttt tcaattggaa ttgttgattt
    99721 ttcacatgat aagatccttt gccttccatc acgacatgca ggatgtaatc attgcgaata
    99781 gcaggaccaa aagaatgaaa cggcatcgtt ttagagaaac cacaaaaatc aaaatacaat
    99841 tctttttcta cttgttgatg ttcctttttt aaaaaaatcg attgctccac gtctatccct
    99901 ccttactcct ttagtataat gcaacaaaaa gttaaataaa agtcacagaa atatattaaa
    99961 aaggaagcga tttcttgtta agtttaagtc attaaaagat ctttgttatt cgttgtaacc
   100021 ggtttactta gtattatata ttgaacagga gaggaataca gattatgaaa agcaaaatga
   100081 tccaacgtgt gtcctacgct ttaggcgctt ttggacacga cacattctat gttacattaa
   100141 gcacttattt tatggtattc gtgacaagcc agatgttcgc aggaacagat aaggcaacga
   100201 atgcaaaaat gattgctaca gttacaagct tagttgtagg tatccgctta gttgaaatta
   100261 tttttgatcc tttgattggt ggcatcatcg ataatactcg tacaaaatac ggtaaattca
   100321 aaccatggtt agttatcggc ggcgttgtta gttccgtact cttggtagca atctttacca
   100381 atttctttgg cttagctact cataatacga ctttatttat catattattt gcaatcgttt
   100441 tcatcttatt ggatagtttt tattcattta aggatatcgc tttttggtca atgattccag
   100501 ctttgagtac ggaaacaaag gaacgtgaaa aatttgctac gtttgctcgt ttcggctctt
   100561 ctctaggtgc aaatggtact actctagtcg ttgtccctat cgttactttc tttacctatc
   100621 ttgttactca taaacatatt gaaggcgctt caggctggtt ctggttcggt gtgattgctg
   100681 ctgttatttc aggcggtact gcgattatca ctgccttggg cacaaaagaa gtcgatactg
   100741 cgatccgtca gcaaaatgaa aaagctggga tcaaagatgt gttcaaagca gttgctcaaa
   100801 atgatcagtt gatgtggctt gcccttgctt atatcgctta tgcgattgcc aatgcagcaa
   100861 caactgccgt attattctac ttcttcaaat atgtacttgg ccaaccaact gaattttgga
   100921 tcgttggtct agttgctgcc ttacttggtt tagtagctgt tccactattc ccaatgctta
   100981 cacgcgtcat ctctcgtcgc tacgtttacc ttggagggat cgcaatgatg atttcttctt
   101041 actttttctt tacgatcgca ggttcaagtt tgccaatcgt tatcatcggg ctagtattgt
   101101 tctacttccc tcaacaattg attttcttat ccgctttgat gacgatcaca gactctgttg
   101161 aatatggtca atggaaaaat ggtatccgta acgaagctgt tactctatca attcgccctt
   101221 tactagataa aatcgctggt gctttgtcta acgggatcgt agggtttgtc gctatcgctt
   101281 ctgggatgac tggtaatgct actgctgctg atatcactgc tcatggcgta acgactttca
   101341 aagcttatgc attctatgct cctgctgctt tgatgatttt ctccgctatt atttttgctt
   101401 ggaagattac attgacagag aaaaaacatg cacaaatcgt tgagaaattg gaaaacaaat
   101461 tggctccagc tgatacaatg gaagatgaac ttcacgatgc agtagatcct tcccattaag
   101521 aaaggatctt gaaaatgaag attacagaaa aagattttgg ccaaggttat cacttgataa
   101581 ccttggagaa caaaaacaag ctagcacttt ctatctctga tttaggtgct agaatcgtca
   101641 gtttaaaatc aaatgatcga gaattagttt tgggatttga caccgctgaa gaatatatcg
   101701 aaaaagatcc gtatatcggt gcttctatcg gtcgcaccgc agggagaatc gaaaatggcc
   101761 acttttctct caatggaaaa acttaccaat tagccacaga tccaaaaact ggacataatc
   101821 tgcatggtgg tgctcctgga tttgaattaa aaaaatggtc ttatgtcatt ttgaatggcg
   101881 aaaatgaagc ttctgtcatt tttactacta caagtcccga cggagaacat ggttttccag
   101941 gtacaatgga tgtggaaatc cgctatactt tgacaaaaga taatatctgg cgagtgacct
   102001 ctcgcggcac cagtgaccaa gatactttat tcaatccgac aaatcatgtt tacttcaact
   102061 tgacgggaga tgcttctcag tcaatcgatc aacatgagct ttggctcaat agcgaagctt
   102121 atgctccttt gcgaacagat agtattccta taggggtaaa agaaaatgct gcaggaagtg
   102181 ctttcgattt tcaaatacct aaaaaattag cgtccgtttt tgctagtgat ttggatcaaa
   102241 aaaatcttgt tgacggaatc gatcatccat ttttcttaaa agaaaccggc ttgggtaaag
   102301 aagccgctcg cttgactagc cccgataaaa gaatccaagt agatattgct acagatgctt
   102361 ctagtgtggt tattttcact gcaaatttcg gcacagaaac accagaaatg cgcaaccgaa
   102421 aactggcaca tcacggtggc atcacatttg agactcaaac agctccaggt gcagagcgct
   102481 tctcagcatt tggttcgatt catttaaaag ccggatcagt atttgaaaca gtgacagaat
   102541 tcaaaatcaa aacaagaaag gaataactca tcatggaaat caaaagaagc ttaaacacaa
   102601 aatttgccga aacattcgga cctaaaaaaa ctacacaata cttctcacca ggacgcatca
   102661 atttgattgg tgaacacaca gattacaatg gaggccatgt cttccccgct tccatcactt
   102721 atggaacgca aggtgtagca gcacctcgag acgataataa aatattagtt tattccacaa
   102781 actttgacga tatcggtgtc attagtttta ctttagatga gctagaatat gataaaaaag
   102841 caaactgggc aaattacgta aaaggaatgg tccttaaatt aaaagaagct ggacactcaa
   102901 tcgatcatgg gtttgagtta ttagtggaag gaacaatccc taatggtgca ggactttcca
   102961 gtagcgcttc attagaatta ttagtaggtg ttgtattaga agatctgttt gatttaaaaa
   103021 cagatcgctt ggaactagtc caaacaggta aaaaagtaga aaatgaattc atcggtgtca
   103081 attcaggtat catggatcag tttgccatcg gcttcggtga gctagatcat gcaatcttat
   103141 tagatacaaa tacgctgaaa tacgaaatgg ttccagtgaa actagatggt tatgcaatcg
   103201 tcatcatgaa tacgaataag cggcgggaat tggcagattc aaaatacaat gaacgccgta
   103261 gcgaatgcga agaagccttg gcacgtttgc aaaaaacttt gcctatctct tctttaggag
   103321 acttagatga agaagaattt gaatcaacta ttgaccaaat cggcgatgat acattgatac
   103381 gcagagctcg ccatgccgtt tctgaaaatc agcggacttt gaaggcaaaa gctgaattag
   103441 aagctgggaa cttagaagca tttggtcaac tgttaaatga ttctcaccac tctcttcgct
   103501 atgattatga agtaactggg atcgaattag atacactagt agatgctgct caaaaacaag
   103561 aaggtgtctt aggtgcacga atgacaggag ctggatttgg tggctgtgcg attgctcttg
   103621 tcaaagaaga aaatatacct gccttcaaaa acaatgtcta tgatgaatac atgaaagttg
   103681 tcggctatgc tccggaattt tatgttgcac acattggaaa tgggacaaca aagatcgatc
   103741 cagaagctgt tcatgtttga taaaaaaatc aacgatctca gctaaaaaca aatagataaa
   103801 aataacctct cagcaatttc caaatgtgag ccttttgctc gtatttgaaa attgctgttt
   103861 tttattgaca cggaaagaga acgtgtgttc taattgtgtt gaagaggtga ttgttatgtg
   103921 ggcgaatcaa aatccggtat ttgtttatga aaaagaacct tcaagagata ttttatgtat
   103981 tgactgcaaa tctttttacg cctccgtaga gtgcgttgaa aaggatcttg atccccttac
   104041 aactaaatta gtagtcatgt cctatccgtc cgattcgaca gaaacacggg gtagcggatt
   104101 aatcttggct tccagtcctg cagcaaaaaa agcttacggc atcaccaata tcagccgtgc
   104161 cagagatctt cccttcccct atccaagtga tttatatatt gttgccccaa ggatggccta
   104221 ttatatggaa aagaacagag aaatcaattc tatctataaa aaatatgcag acgaagcgaa
   104281 ccatcatgtc tattccgtcg atgaaagctt ccttgatgta acaaatagca tggcactctt
   104341 tggtaaaaca aatgcgtacg acatggctaa actgatccat aaagatgtgt ttgagcagac
   104401 cggaatctac acgactatag gaattggcga taacccgcta cttgctaaac tagccttaga
   104461 caatggctca aaagacggaa agcaaatgtt tgctgaatgg cgttatgaag atgtaccaga
   104521 aaagttatgg aaaatctcag atatcactga cttttgggga atcggcaaac gaacagcaaa
   104581 acgtctgaaa caaatgggta tacattctgt ttatgattta gctcacgcgg attattatca
   104641 cttgaaaagc aagctagggg tcatcggtac tcagctttat gcccatgctt ggggcatcaa
   104701 tcgaagtttt ttgggacaag aatatacacc aaaatcaaaa agtatcggaa atagtcaaat
   104761 cctagataga gattatacaa gacgagaaga aatcgagatc gttatcaaag aaatggccga
   104821 ccaagtcggc actcgcttga gacgatctgc agcaaaaaca caagtagtca gcttatgggt
   104881 aggatactct ttaggctatc ttgatccaaa tggcaagacc gggtttcacc agcaaatgaa
   104941 aatcgaagcg acaaatgcta gcagagatct agcagatgct ttattgacca ttttccacca
   105001 gcattaccac taccaggata ttcggcgtgt aggcgtgaac tgttccgacc tcgtatacgc
   105061 gacaggttta cagcttaacc tttttgaaga tcctgaaaag cagataaatg aagcgaaagt
   105121 tgattttgtt gtcgatacga ttagaaaaaa atacggcttt caatcaatca tccatgcgca
   105181 tagtctcttg caaggaggac gcgccatcgc acgtagttct ctcgttggcg ggcatgcagg
   105241 tggtatgagt ggattagaag gtggaaaaga tgagacggac agcaaaaaaa ttcattgact
   105301 ataacgagta tcgagatcgg ccatttggat taaaatgggg gactgctttt gcgatggaag
   105361 aactagtcaa cggtatcaaa aaaaatgaag aagaagcacg caaacagcct cttcctaaac
   105421 aacaaatgac attgcaagaa atcgatagta tactgacaga agccttttta tctcgtaaag
   105481 cagtaatcat tcagctcaat ttaaaagatg aatttggaag actcttggat gaggtcgaag
   105541 ggcacttcat tggtgaagcc tatgaagatt actttatgat tgaccatcag ccgatattgt
   105601 gggaagacgt acggtatatt gagttaaagg aaacaaaaaa atggtttgtg acatgagagg
   105661 ttgtgacaga agtgatcaac ttcaaaaaat aagaaaggat ttttcgaaaa ttgcttctta
   105721 aatttttgtg gaattttggc ttatttttcg aagaagcaac ttctggaaca acgtatatta
   105781 gatatcagag gttgtgaaaa agtcgcttag ttttgagtaa caagccaagg cgctgatttc
   105841 acaacctctg tctatctatc catctattcg gtaagattca tgcatgacgt cttctttatt
   105901 tagtatgtag agcccttttt cttctgacca ttcaacataa atcagctgtt ttacatctgc
   105961 atagccttct ttcttcaagt tctccataag ccatgcttca gtcaattgat tggactgaag
   106021 cactttatgc tgaatttgcc cttcatctac aagcaggatc gataaagctt tgtcttcatc
   106081 tgattttttc aatacactca tttgaccggc attctctagg ataacatgtt tggcattttc
   106141 aagaaaaaag cattcttgct gtcttaagat tgctcgcaac tgctccatct cgatatggtt
   106201 atttgtcaac tctgtcatgt tgatgacgcc gtctttgatt agaacagatg gctcgccttt
   106261 gacccaacga ttgacctttt catttttttg gacgatacgt tcgataccat aaatcattac
   106321 tgcccaaagc gcaatggcaa ataggacatg ccctacatgg acattgtcat cataggttga
   106381 ttcttctaag atcccaccta aaacaagcgt atagactaaa tcaaacggtg tgatttctga
   106441 catggatttc ttcccaagca aacgtaccac taataataaa ccgatcaacc cgaacaccag
   106501 tttcattgta attgaaaaaa tcattttttc tccccctaac tatctgttaa ttaaattata
   106561 tatgctttct cacgaacacg catggaatat acaaggaaga aatgtatcct tttactaaaa
   106621 aaaggactgt gacactgtag tgacccccaa aagttagact tttttggagt ggagaaatcc
   106681 actccttttt tttatgctct aaaatgatat ttttacacaa ccgttacggt tgttttacga
   106741 aattggacg
//
LOCUS       DAFBVQ010000003        98433 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.003, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000003 DAFBVQ010000000
VERSION     DAFBVQ010000003.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 98433)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 98433)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..98433
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.003"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            476..1339
                     /locus_tag="LLC22_000200"
     CDS             476..1339
                     /locus_tag="LLC22_000200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5433508.1"
                     /translation="MYQIVTDSCCDLPYHVLAKEKVDFLSMNLQLNDQELVDDLGKTF
                     NYDRYMNQLKNGAMPTTSQINVGRYLEFFRSYAEKQIPVLYVAFSSGLSGSYSSALQA
                     VELLKEEYEDPEIYVFDTKAASIGEGLLVLEAVRLKKEGKSIEETLEWLESNYLKVHS
                     WVTVDDLKYLERGGRISKASATLGSLLSVKPIITVDKEGRLTNVDKVRGRNKSIQTIV
                     NETVKTIVAPLDQIVYVAYAGDLESAEKAKRLLEEQIKMKDVKLYPLGPTIASHTGYG
                     CIAIFSMGISR"
     gene            complement(1468..3090)
                     /locus_tag="LLC22_000201"
     CDS             complement(1468..3090)
                     /locus_tag="LLC22_000201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629689.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5433509.1"
                     /translation="MITVNDVSLHFSDRKLFDDVNIKFTPGNCYGLIGANGAGKSTFL
                     KVLSGDLQPSTGSVTMGPDERMAVLKQNHYDYEDYTVLETVIMGHKRLYEVLKEKDAI
                     YMKEDFTDEDGIRAAELEGEFAELNGWEAEPEAAVLLQGLNIPEELHHQQMSELTGGQ
                     KVKVLLAQTLFGKPDVLLLDEPTNGLDIQSINWLEEFLINFENTVIVVSHDRHFLNKV
                     CTHMADLDFGKIKLYVGNYDFWLESSQLAAKLQANANAKKEEQIKELQEFIARFSANA
                     SKSKQATSRKKMLEKITLDDIQPSSRRYPFVGFKPEREIGNDLLQVENVSVTIDGKKI
                     LDDISFNLSKEDKVAFVAENDITTTTLFKVIMGEITPDTGTVRWGVTTSNSYLPKDTT
                     KEFDTDLTILDWLRQYASKEEDDNTFLRSFLGRMLFSGEEVLKPVNVLSGGEKVRCML
                     SKMMLSKANVLVLDDPTNHLDLESITALNDGLMAFTGSILFASHDHQFIQTLANRIIA
                     VSDKGVIDRADTTYDEFLENADIQKQLNELWA"
     gene            3339..3860
                     /locus_tag="LLC22_000202"
     CDS             3339..3860
                     /locus_tag="LLC22_000202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBK5433510.1"
                     /translation="MDEKRTIDWGSLILGILFVLVSLLSFQDPVGNLVAIVVVFAIFA
                     FIKGIFELFVRNRLKELTGYKGKMPLIIGIIDILVGVFFLFNIGAGVAALPFVFAVWF
                     IADSVLALFTADLARGVSEGYYWFTIIVNILGILLGIFLLFNPISSALTLSFLVGFYF
                     MLFGITHIVYAFR"
     gene            complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LLC22_000203"
     CDS             complement(4046..5776)
                     /gene="spxB"
                     /locus_tag="LLC22_000203"
                     /EC_number="1.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate oxidase"
                     /protein_id="HBK5433511.1"
                     /translation="MSKINAGIAMVKVLESWGIDHIYGIPGGSFNSIMDALYQEKTEI
                     NYIQVRHEEVGALAAAADAKLTGKVGAVFGSAGPGATHLINGLYDAQMDHVPLVAFLG
                     QVASTSMNYNSFQELNENPIFADVSVYNRTVMTPQSLPHVVDEAIKAAYEHKGVAIVT
                     IPVDLGFEEIDEQPFSTAHTHKTSVILPEEKDLLAALPYLEKAKKPVLYVGQGTRNGF
                     PQIKEFSEHFSVPVVASVLAKGIIPDDYENFLGFAGRVATKPGNEALAEADLILFVGS
                     DFPFGRAFFNPTAEFIQIDIDASKFGRRHETSLSILGDANTALQRLVELGDARPADSW
                     YLANQENKEKWVNWLKSFEDREEEPIRPEAVYKEINRIAEDDAIFVTDVGNTTIHSIR
                     LLNMNGKQKHTTSGWFATMGNGVPGGIAAQLSYPEKQVFTLSGDGGFAMVMQDIITQV
                     KYQLPIINVVFSNDSFGFIEAEQEDTEQKKFGVFLEDADFGKVGEALGANSFTVTEYS
                     QLRFAFDAAAKSDRPVVIDVKINNKRPLPVEDLHLDPRKYSEEEIQAFKEKYEVHDLP
                     VLNELYEKRL"
     gene            5941..6759
                     /locus_tag="LLC22_000204"
     CDS             5941..6759
                     /locus_tag="LLC22_000204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ZIP family metal transporter"
                     /protein_id="HBK5433512.1"
                     /translation="MVEWLLRLEPWQQALAGTAFTYFMTALGAGLVFFFKEIKKEVLN
                     LMLGFASGVMIAASFWSLLDPAITKAEENGDIAWLVVSIGFGLGGVFLYMADKTLPHM
                     HFGPQHEAEGLPTHLKRTILLVFSITLHNIPEGLAVGVAFGAAATADNPTAAILAAVS
                     VALGIGIQNFPEGAAVSIPLRQEGLSRKKAFVYGQASGIVEPIAGVIGALLVTKVELL
                     LPYALAFAAGAMIYVVVEELIPEAQQTLSSKRHFAVFGVMSGFIIMMILDVALG"
     gene            complement(6862..7059)
                     /locus_tag="LLC22_000205"
     CDS             complement(6862..7059)
                     /locus_tag="LLC22_000205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433513.1"
                     /translation="MRQKNMFLNIFMVLLVLIAASFVISLFVSVLSGLLWFAVKVLIP
                     IALIIWLVRWIKGNTHRKNYY"
     gene            7228..7806
                     /locus_tag="LLC22_000206"
     CDS             7228..7806
                     /locus_tag="LLC22_000206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292646.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBK5433514.1"
                     /translation="MPKNRLEAFTDAVIAIIMTILVLELHEPNGDTWEALAALGYRFF
                     IYIVSFIILAIYWNNHHHLFQVVHKINGRVLWANSFFVFALSLFPFATSWISEYINSL
                     APEMTYGFVTLTANIAYYILAKELVKANKGHEKALKAMLNNYKKSYLSIGLNVLGIVL
                     GYLVAPVAVLIANIVILAAWIIPSRTIESQYR"
     gene            7901..8038
                     /locus_tag="LLC22_000207"
     CDS             7901..8038
                     /locus_tag="LLC22_000207"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433515.1"
                     /translation="MDQKRIHVGLITSFVTMLIYLDQGHLTWTVVGVVGFLTLFTAIK
                     K"
     gene            complement(8851..9354)
                     /locus_tag="LLC22_000208"
     CDS             complement(8851..9354)
                     /locus_tag="LLC22_000208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBK5433516.1"
                     /translation="MRYVSKFLLGIYLFFLLWLILFKLSFNLPQFLTYSYSNVNLVPF
                     STFSFENTTVLRETTYNLIVFFPFGVLLNVNFKRLSFSKKLGIIFLVSFLAELIQFLF
                     GIGVADITDLITNTTGGLIGLWAYQLLNKHLSTNKLDRLAIILGYILFLFLIVAFLFL
                     TRTVRLQ"
     gene            9713..10738
                     /locus_tag="LLC22_000209"
     CDS             9713..10738
                     /locus_tag="LLC22_000209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5433517.1"
                     /translation="MFKTYFRFNKIQDNPFRIMNLMLLIFIVLWLGYINHDFLISSFS
                     SLGIFTFFYYQNIPMKYLLKRMFLIGCGLLVAFVLGILSTYVLWLEPFAVALVAFSSR
                     FVLRLFHISKPGGLFFAMLSAMGTSMQLPIAQLPIVSLYFFMGVVFALIAAVITKLLD
                     SRPEQTIEKATLKERFHEEPLVIIDSVFYSAALFLSVYVSHGLNLHNPYWLTLSCASI
                     LLAENLDAMKHRQVQYLIGSMGGLCVSAFLSFVPFTQLQTIFLITFLYGIAQFLVARN
                     YAVANIFLNPMALMLSTLIRGAYLISLIEYRFLGIVIGSFIGLGVAWVMTVGLQHYLT
                     VVRQKLE"
     gene            11085..11963
                     /locus_tag="LLC22_000210"
     CDS             11085..11963
                     /locus_tag="LLC22_000210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5596 domain-containing protein"
                     /protein_id="HBK5433518.1"
                     /translation="MRFKDMKRGNLMKKISNEIQILAETLTLPKVVIEQMIVQAKNIL
                     DEVFEQYSHELMDPNKAKATAKKIDKVYEEEPFAALAIYLYAASQSWKKIYQPLKIPR
                     TIYLATMNAFTRFIHEHFQVTGSYRFDRGFWIWHYTSGLIFRIGELEYEMTYFPKGYT
                     DLRLEGKQCLSLHIPSDADLSQNKIRDSYESAIRFFELYFPDYHYQVMYTDTWLLSPN
                     LTKWLKKESKICLFAADYRLLSVDEQDDSGVPWIFGRVDAQIHDYPESTSLQRQAKEQ
                     LLAGEHIGSGLGILTS"
     gene            12439..12555
                     /locus_tag="LLC22_000211"
     CDS             12439..12555
                     /locus_tag="LLC22_000211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002383181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBK5433519.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKDVKRNSGKR"
     gene            13483..13821
                     /locus_tag="LLC22_000212"
     CDS             13483..13821
                     /locus_tag="LLC22_000212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433520.1"
                     /translation="MTQPVSSEEHDNLFRATEEFKKYQENIVPETPLASEPITDIDGN
                     QIGWYIQYEVMVVNNDSIVKNTVGLELTPIEKVSSLLTYIYTDESDETEIILTDYSKI
                     ATDKKYILWM"
     gene            13915..14145
                     /locus_tag="LLC22_000213"
     CDS             13915..14145
                     /locus_tag="LLC22_000213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433521.1"
                     /translation="MLVEKGKENIYYVNVAKVREDENEWKEFKSRYSINSTPTFTVYR
                     EGSIEKTVFWTKESGMSLAEVEEFLDYVSMQQ"
     gene            14545..14916
                     /locus_tag="LLC22_000214"
     CDS             14545..14916
                     /locus_tag="LLC22_000214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cro/Cl family transcriptional regulator"
                     /protein_id="HBK5433522.1"
                     /translation="MRDYVTDKTQEVINQSQSLNELSDKAKEEAVAIISSGISDYIDM
                     SGEINYGDKDKIVRMIKAFIKTFDVKADLKFNDTYLVGKLINILGTEKDTETFISSLS
                     MLFTDKHFSTQLGGEELVEIF"
     gene            complement(15190..15882)
                     /locus_tag="LLC22_000215"
     CDS             complement(15190..15882)
                     /locus_tag="LLC22_000215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5433523.1"
                     /translation="MKGIIFDFNGTMFLDSHLHEAAWLHMIHDHTKDGLSDEDILKNI
                     HGRTNTEILKHFISEHLTASEIAVLSEEKESYYRMLCLQNENELQLTKGLEATLDQLT
                     DQQIPLTIATATVKENVAFYFDIFDLARWFDWDKIVYDDGSFPGKPQPDIFLKAADKL
                     SLAPADCLVIEDAYSGLLAAKRAGIGTIIAIDPFGKNKTVFEQAQLNKDGTIKDFTGF
                     WTEHLSATSVNS"
     gene            complement(15885..16670)
                     /locus_tag="LLC22_000216"
     CDS             complement(15885..16670)
                     /locus_tag="LLC22_000216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738601.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5433524.1"
                     /translation="MLKKERLLTIVEMVNKKGILTVNEIINQLDVSDMTVRRDLDELE
                     KSGKLLRVHGGAQSLSYTLDQELSHTEKATLQIQEKKEIAATAASLIHEGETIFLGPG
                     TTIELLATHLLNKKIRIITNNYPVFDILAQADGPEILLIGGDFRKNTGAFVGPITNDN
                     LRRLKFTKAFISSNGVHNEAISTYSTEEGEAQQIALNNSRKKYLLVDNKKFNRDDFYV
                     FYNLHDFDLLITDRQISREVQEHYAQYVDLQIADSTENTTIGA"
     gene            16907..18307
                     /gene="lacG"
                     /locus_tag="LLC22_000217"
     CDS             16907..18307
                     /gene="lacG"
                     /locus_tag="LLC22_000217"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBK5433525.1"
                     /translation="MLKLPEDFIFGGATAAYQVEGATKEGGKGAVAWDDFLEEQGRFS
                     PDPASDFYHQYAKDIELCERFGVNGLRLSIAWSRIFPDGAGKPNPEGIAFYHRVFEEC
                     KKRNVTPFVTLHHFDTPKRLFDHGDFLNRETIEAFVSYAIFCFHEFKEVKVWSTFNEI
                     YPVATNQYLLGVFPPGIKYDFTKIVACLHNMMVAHARVVNYFKENELPGEIGVVHSLE
                     TKYAATDAPEDKHAAFLDDALSIRFLLDATYLGYYSTETLTALDEICEANQASYHFPE
                     EDFVELKKASTRNDYLGINHYQCHFVKAYDGENAIHHNGTGEKGTSVYKVKGIGERIY
                     KEGIPRTDWDWLIYPEGLYDLLLRIKSDYPHYNKIYITENGMGYKDQFEDGIIMDQPR
                     IDYLRVYLESLSKAITAGVNVKGYFLWSLMDLFSWTNGYNKRYGLFYVDFETQKRYPK
                     ESAYWYKLVSETKTII"
     gene            18332..18649
                     /locus_tag="LLC22_000218"
     CDS             18332..18649
                     /locus_tag="LLC22_000218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010749967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK5433526.1"
                     /translation="MNKEELQMLGFEIVAYSGDARSTLLKLLKEVRQGNFEHVDSALK
                     EADENLTLAHNSQTKILAEEASGKEMEMGFIFIHGQDHLMTTLLLRDLIQDFIVLYRQ
                     NQG"
     gene            18662..20335
                     /locus_tag="LLC22_000219"
     CDS             18662..20335
                     /locus_tag="LLC22_000219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose transporter subunit IIBC"
                     /protein_id="HBK5433527.1"
                     /translation="MDGIIKQIEKGKPFFEKISRNSYLGAVRDGFLTAMPAILFSSIF
                     ILIAAVPEIFGYQWPESVSTWLWKVYNYSMGVVGLLVSATTARCLADSMNRRLPKNKV
                     INTTSVMLASVVSFLLLSVSPIEGGFSTEYMGTKGLLASFVAAFLTVNLYKFCVLKDI
                     TIKMPKEVPGTISQTFRDIFPFSFSVFAAVLIDLGIRQIFQISFAEAIITVLQPLFTA
                     ADGYLGIAIIWGAMALFWFVGVHGPSIVEPAIAAIIYANVETNLQLFNSGEQASKVLT
                     VGLGNFVGTMGGTGATLVVPFIFLLFAKSKQLKAVGKASFIPVSFAVNEPLLFAAPMI
                     LNPYFFIPFLLTPVVNVCLFKFFVDVLGMNSFMYVLPWATPAPIGLVLGTGMGILAFV
                     LAAVLIVVDFLIYLPFCKAYDAVLVEKEAQKAEVIATEEGASADVREEVPVAASQVIS
                     DANKEINVLVLCAGAGTSAMLANALKKGASESKAPISAMAGAYGSHYEMLQDFDMVVL
                     APQVNSYYDDIKEDTDRLGIKLVATKGAEYIGLTRDPEKAVQFILNQFQ"
     gene            20349..21980
                     /locus_tag="LLC22_000220"
     CDS             20349..21980
                     /locus_tag="LLC22_000220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase 53 family protein"
                     /protein_id="HBK5433528.1"
                     /translation="MKMGIWLRKAVLFAAVLGALGAVSKTVEASASEFIRGADISILS
                     DMEKSGAKYYEDDISKDALEILKNNGVNYVRLRLWQDPYNSNGESYGAGTNDLETTID
                     LAKRAKNLGLKVLLDFHYSDFWVDPGKQNLPKAWQGLTFEEMNTALYDYTKNVLSEMK
                     QLDVYPDMVQIGNELNSGMLWPYGKSWGEGGGEFDRLAAFLKSGIQAVRDTQPKTTPV
                     MLHLADGGDTGAFTWWFDEITSRGVSFDLIGVSYYPYWHGSMNELQTNMNAISQRYGK
                     EVIVVETAYGHTTANADTMPNAFGEAEAAAGGYEPTPTGQAEYLLDLADRIQAVPNNR
                     GAGFFYWEPLWYNGNVSWATQAGMNYLSVQSTMGNEWDNQAMFDFAGNALPSLRAFKQ
                     AGAQINLVKNASFESDGPTTSPSNWQTWFQQGTAKGTIKTEAGTFFGDYKLTFWQDQA
                     YEASAYQNVSGISKGTYTLSAYVMSGGEFDTNQLYIKNYGGAELNTAVVKTSEWTKIT
                     IKDIPITTGVCEIGVYSKASGNAWTNVDFVSLVKQ"
     gene            22852..24042
                     /locus_tag="LLC22_000221"
     CDS             22852..24042
                     /locus_tag="LLC22_000221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISLgar5 family transposase"
                     /protein_id="HBK5433529.1"
                     /translation="MNDFTTEILKTLANKGDLNELFRVHLEKAVNTLLKTELTAFLDY
                     EKYDRIGFNTGNSRNGSYDRTVKTEYGELHLQIPRDRNGEFKQQTVPAYRRTNDTLEE
                     TVIHLFRKGITMSEIADLIEKMYGHYYTPQTMSNITKSFTEEVTAFNGRELHDRYAAI
                     YMDATYIPLKRKTVAKEAIHIAVGIRPDGSKEVLSYAIAPTESITIWEEILLDLQERG
                     LKNVLLFITDGLKGMVGAISRFYPKARFQHCCVHVSRNISHKVRVDDRKEVCDDFKMV
                     YQASSKEVALEARGTFAEKWKTSYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIE
                     SFNKQIKKYSHRKEQFQNEESMERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQ
                     LIEN"
     gene            24176..26365
                     /locus_tag="LLC22_000222"
     CDS             24176..26365
                     /locus_tag="LLC22_000222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5433530.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            26362..28155
                     /locus_tag="LLC22_000223"
     CDS             26362..28155
                     /locus_tag="LLC22_000223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK5433531.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            28355..28669
                     /locus_tag="LLC22_000224"
     CDS             28355..28669
                     /locus_tag="LLC22_000224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5433532.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            28690..29067
                     /locus_tag="LLC22_000225"
     CDS             28690..29067
                     /locus_tag="LLC22_000225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5433533.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            29077..29850
                     /locus_tag="LLC22_000226"
     CDS             29077..29850
                     /locus_tag="LLC22_000226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433534.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            29872..31275
                     /locus_tag="LLC22_000227"
     CDS             29872..31275
                     /locus_tag="LLC22_000227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBK5433535.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            31457..32641
                     /locus_tag="LLC22_000228"
     CDS             31457..32641
                     /locus_tag="LLC22_000228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5433536.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            32638..32928
                     /locus_tag="LLC22_000229"
     CDS             32638..32928
                     /locus_tag="LLC22_000229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433537.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            32925..33146
                     /locus_tag="LLC22_000230"
     CDS             32925..33146
                     /locus_tag="LLC22_000230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433538.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            33188..33967
                     /locus_tag="LLC22_000231"
     CDS             33188..33967
                     /locus_tag="LLC22_000231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBK5433539.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            34034..34528
                     /locus_tag="LLC22_000232"
     CDS             34034..34528
                     /locus_tag="LLC22_000232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK5433540.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            34584..35222
                     /locus_tag="LLC22_000233"
     CDS             34584..35222
                     /locus_tag="LLC22_000233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433541.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            35294..35689
                     /locus_tag="LLC22_000234"
     CDS             35294..35689
                     /locus_tag="LLC22_000234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5433542.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            35673..38126
                     /locus_tag="LLC22_000235"
     CDS             35673..38126
                     /locus_tag="LLC22_000235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5433543.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            38123..40150
                     /locus_tag="LLC22_000236"
     CDS             38123..40150
                     /locus_tag="LLC22_000236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433544.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            40147..41169
                     /locus_tag="LLC22_000237"
     CDS             40147..41169
                     /locus_tag="LLC22_000237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK5433545.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            41186..42115
                     /locus_tag="LLC22_000238"
     CDS             41186..42115
                     /locus_tag="LLC22_000238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5433546.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            42360..42476
                     /locus_tag="LLC22_000239"
     CDS             42360..42476
                     /locus_tag="LLC22_000239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBK5433547.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            42492..44411
                     /gene="tet(M)"
                     /locus_tag="LLC22_000240"
     CDS             42492..44411
                     /gene="tet(M)"
                     /locus_tag="LLC22_000240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBK5433548.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            44509..44697
                     /locus_tag="LLC22_000241"
     CDS             44509..44697
                     /locus_tag="LLC22_000241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBK5433549.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(44755..45108)
                     /locus_tag="LLC22_000242"
     CDS             complement(44755..45108)
                     /locus_tag="LLC22_000242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433550.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            45639..46061
                     /locus_tag="LLC22_000243"
     CDS             45639..46061
                     /locus_tag="LLC22_000243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5433551.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            46058..46288
                     /locus_tag="LLC22_000244"
     CDS             46058..46288
                     /locus_tag="LLC22_000244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433552.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            46786..46986
                     /locus_tag="LLC22_000245"
     CDS             46786..46986
                     /locus_tag="LLC22_000245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBK5433553.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            47013..48206
                     /locus_tag="LLC22_000246"
     CDS             47013..48206
                     /locus_tag="LLC22_000246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5433554.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(48274..49839)
                     /gene="guaA"
                     /locus_tag="LLC22_000247"
     CDS             complement(48274..49839)
                     /gene="guaA"
                     /locus_tag="LLC22_000247"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBK5433555.1"
                     /translation="MTNVADMTNVEKIIVLDYGSQYNQLITRRIRDLGVFSELLSHRI
                     TAEEVKAMNPKGIILSGGPNSVYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGS
                     VEPAKNREYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCP
                     IASIQDTTRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIR
                     EQVGDKKVLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGK
                     FGLNIIKVDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQG
                     TLYTDVIESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDS
                     IVWRQPFPGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGI
                     RSVGVMGDGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVY
                     DITSKPPATVEWE"
     gene            complement(49898..50821)
                     /locus_tag="LLC22_000248"
     CDS             complement(49898..50821)
                     /locus_tag="LLC22_000248"
                     /EC_number="2.7.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I pantothenate kinase"
                     /protein_id="HBK5433556.1"
                     /translation="MNDPMNYYRVAREEWREFYRNGQAPLTQDELDNIKSLNDRISMQ
                     DVRDIYVPLAHLIYLYMKEFESLFLSKGLFLHKYVEVPPFIIGIAGSVAVGKSTTARL
                     LQTILSRTFKRRNVQLITTDGFLYPNRILKERGIMDRKGFPESYDMEMLIDFLNRVKS
                     GQEEIKVPVYSHDVYDIIPDKYELIQQPDILIVEGINTLQLPANQQIYVSDFFDFSVY
                     VDADPVLIEKWYLDRFGALLDTAFQNPENYYYRFAIGDREEAFKMAKDVWKNVNLKNL
                     QEYILPTRGRADIILHKTENHIIDSIFMRKY"
     gene            51017..51622
                     /locus_tag="LLC22_000249"
     CDS             51017..51622
                     /locus_tag="LLC22_000249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5433557.1"
                     /translation="MTNHYYSERPDTAHDFEQWAFELKGRTFQFVTDSGVFSRETVDY
                     GSRVLIDAFDWEELPDEGKILDVGCGYGPIGLALAFATQRFVEMVDINERAVSLAQGN
                     AKRNQIEHVDIHQSNIYEAVHEETYAAIVSNPPIRAGKKVVHEILTGAYPRLKKGGTL
                     TIVIQKKQGAPSAQKKMEETFGNAEIVTKDKGYYIIKSVKE"
     gene            51930..52946
                     /locus_tag="LLC22_000250"
     CDS             51930..52946
                     /locus_tag="LLC22_000250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBK5433558.1"
                     /translation="MKLTIRDIAEMAGVSVTTVSQILNNKGSRFSDKTRKKVLSIVNE
                     HHYKPDYFASNVINRHSKTIGMIVPDVTDFFFSKLIEGVESYLNPLGYVIMLCNSRHS
                     QENEIKYLQELSHRSVDGILLATPNILPEKYALDSGFYQKMPIILIDRGLNRRDNGRL
                     IVKEYEGAYQAVSLFIENGHTKIGMLKETTGYYQLEERFNGYRHALKDHGLPFNGKFV
                     EHGELTVQGGYTASKKLLKHKDITAIFCGNDAMAIGCYQAIDELGKKIPEDISVIGFD
                     GLKLSEYMIPQLTTVQQPSFDIGFYAARFLIDTIEFPQRKVPNKVFETKLIIRESVKV
                     LTKG"
     gene            53087..54388
                     /locus_tag="LLC22_000251"
     CDS             53087..54388
                     /locus_tag="LLC22_000251"
                     /EC_number="2.4.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019724048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrimidine-nucleoside phosphorylase"
                     /protein_id="HBK5433559.1"
                     /translation="MRMVDLIEKKRDGNELSKEEIEYIVTNYTNGKIPDYQVSALLMA
                     IFYQDMTNEEITNLTLAIANSGDVIDLSSLEGIKVDKHSTGGVGDTTTLILAPLVASV
                     GVTVAKMSGRGLGYTGGTLDKLEAIPGFQIELSDEEFVRIVNESKVAVIGQSGNLAPA
                     DKKLYALRDVTATVDSLPLIASSIMSKKIAAGADAIVLDVTTGDGAFMKNIEDARRLA
                     KTMTSIGKLANRETVAVISDMSEPLGEAIGNSLEVVEAIETLQGNGPEDLVEMCYALG
                     SQMVVLAGKAKTTDEARTLLQEALESGKALAKFKEMIQNQGGDPAIVEHPERILTARY
                     TMELPAKQSGVVSKIVANELGIAAMMLGAGRKTKEEDIDHAVGLKLHKKIGDTVTKGE
                     SLLTIYSNDEEITSVIELLYKNIEIGESAMKPTLIHDIITE"
     gene            54434..55096
                     /gene="deoC"
                     /locus_tag="LLC22_000252"
     CDS             54434..55096
                     /gene="deoC"
                     /locus_tag="LLC22_000252"
                     /EC_number="4.1.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribose-phosphate aldolase"
                     /protein_id="HBK5433560.1"
                     /translation="MELNRMIDHTILKADASKEAVMQIIEEAKKYHFYSVCINPAWVA
                     LAKEQLQGEPVAVCTVIGFPLGANTPETKAFETTDAINNGADEVDMVINIGALKSKDD
                     QQVQKDIEAVVEAAKDRALVKVIIETSLLDREEIIRACEIAKAAGADFVKTSTGFSTG
                     GAKVEDVRLMRETVGPEMGVKASGGIHNEEEAMAMIEAGATRIGTSAGVAIVSGSTGE
                     GY"
     gene            55117..55515
                     /locus_tag="LLC22_000253"
     CDS             55117..55515
                     /locus_tag="LLC22_000253"
                     /EC_number="3.5.4.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytidine deaminase"
                     /protein_id="HBK5433561.1"
                     /translation="MAELKQEWINTAIEALDKAYVPYSHFPVGACLVTESGKIYQGIN
                     IENASFGLTNCAERTAFFKAVSEGEKTFTHLVVAGHTPDPISPCGACRQVMAEFCSPD
                     MPVTLVGDNGVTKATTVRALLPYAFTEKDL"
     gene            55581..56663
                     /locus_tag="LLC22_000254"
     CDS             55581..56663
                     /locus_tag="LLC22_000254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BMP family ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5433562.1"
                     /translation="MKKAKLFGLGAVALAAGLFLGACGNNGSTDSSGGKSSSDTTTAA
                     LITDTGGVDDRSFNQSAWEGLEKWGKDQGLSRGNDGFQYFQSSNESDYIPNIDQALNA
                     GFKTIFGIGYKLKPAIQEQATNNTGTNFVIIDDVIDGLDNVVSATFKDNEASYLAGVA
                     AAYTTETNVVGFIGGVKGEVIDRFDAGFKAGVDAGAKELGKEIKVLNQYAGDFSAPDK
                     GRSIAQGMYAQNADIIFHASGGTGNGVFQEAKSLNESGDKKVWVIGVDRDQSDEGEYT
                     LNGEKKNFTLTSTLKAVGTVVEDLAQKSADGKFPGGEHTVYGLKEDGVGLTEGQLSDE
                     AKKAVDEAKEKIISGDVKVPETPEEN"
     gene            56875..58437
                     /locus_tag="LLC22_000255"
     CDS             56875..58437
                     /locus_tag="LLC22_000255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5433563.1"
                     /translation="MVQENIVIEMQNITKEFGTFKANDNINLQVKAGEIHALLGENGA
                     GKSTLMNVLSGLLEPTSGKILMRGKEVKITSPTKANQLGIGMVHQHFMLVDAFTVTEN
                     IVLGSEPSRAGMLDHKKARKEIQKVSEQYGLSVNPDAYVRDISVGMEQRVEILKTLYR
                     GADVLIFDEPTAVLTPQEIDELIVIMKELVKEGKSIILITHKLDEIKAVADRCTVIRR
                     GKGIGTVNVKDVTSQQLADMMVGRTVSFKTMKKEAKPQEVVLSIENLVVKENRGLEAV
                     KNLNLEVRAGEVLGIAGIDGNGQSELIQALTGLRKAESGHIKLKGEDITNKKPRKITE
                     HGVGHVPEDRHKYGLVLDMTLSENIALQTYHQKPYSKNGMLNYSVMNEHARELIEEYD
                     VRTTNELVPAKALSGGNQQKAIIAREVDRDPDLLIVANPTRGLDVGAIEFIHKRLIEQ
                     RDKYKAVLLISFELEEILNVSDRIAVIHEGEIVGIVDPKETSENELGLLMAGYTLEEA
                     RKELEKGAGAHE"
     gene            58430..59563
                     /locus_tag="LLC22_000256"
     CDS             58430..59563
                     /locus_tag="LLC22_000256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5433564.1"
                     /translation="MNDRSEKFRNLLVPVLSVVLGLILGAILMAAFGFQPIQGYSSML
                     DAALGSQRGIGETLRQATPLIFTALGFSVANSAGFFNIGLSGQALCGWIVSVWVALAF
                     PDLPKVVLLPLCVILGALAGAMAAAVPGLLRAFFGTSEVIVTIMMNYILLYVSTFALH
                     EVMPESYRSSLDSSNMISQNASLRLPWLTQAFGGSRVNSGLFLAIIALIFVWLLMKKT
                     TLGFEIRSVGLNPFASEYAGMSSKRTIVLSMVISGALAGLGGVVEGLGTYQNFFVQTT
                     SLSIGFDGMAVSLLGSGSAIGILLSAILFSILKIGGLGMQTGAGVPFEIVNVSIALII
                     FFVGINFLIRFVMAKVFQGKKQEEIVATIESKPTNQNHEGGEL"
     gene            59563..60519
                     /locus_tag="LLC22_000257"
     CDS             59563..60519
                     /locus_tag="LLC22_000257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5433565.1"
                     /translation="MSTIELIALILTSTLVYSTPLILTSLGGTFSERSGIVNVGLEGI
                     MVMGAFSSIVFNLTMSPSLGSMTPWIAILVGGVVGILFSLIHAVATVSLRADHIISGT
                     VINLMAPALGVFLIKAWYGKGQTDNITQNLGYFSFPGLADIPVIGPIFFKNTFLPAYC
                     AILIAVLAWVIIFKTKFGLRLRSVGENPQAADTLGINVYAMRYSGVLISGLLGGMGGA
                     VFAQSISGNFSAGTIVGQGFISMAAMIFGKWNPLGAMGASLFFGFAQSLSIIGAQLPV
                     ISSIPPVLLQIAPYLLTIIVLVVFLGKASGPKANGKNYIKSK"
     gene            60618..61784
                     /gene="deoB"
                     /locus_tag="LLC22_000258"
     CDS             60618..61784
                     /gene="deoB"
                     /locus_tag="LLC22_000258"
                     /EC_number="5.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopentomutase"
                     /protein_id="HBK5433566.1"
                     /translation="MFKRVHLIVMDSVGIGEAPDADKFGDVGSDTLGHIAKEAGLNVP
                     HLEQLGLGTIRPLEGVESVKDHQGYATKLEEVSVGKDTMTGHWEIMGLNIKTPFRVFP
                     NGFPDDLIKQIEEFSGRKVVCNKPYSGTAVIDDYGEHQMKTGDLIVYTSADPVLQIAA
                     HEEIIPLEELYRICQFVRDITKDDPYMIGRIIARPYVGEPGDFTRTSNRHDYALNPFG
                     HTVLDSLKEAGKDVIAVGKINDIFNGQGITESVRTKSNMDGVDQLLKVMKNDFSGISF
                     TNLVDFDALYGHRRDVVGYAHAIEEFDLRIPELLEAMEEDDLLMITADHGNDPTFTGT
                     DHTREYVPLLVYSKKMKEQGALPQGYYSDISATIAENFSVSSTENGESFLKLLK"
     gene            61808..62626
                     /locus_tag="LLC22_000259"
     CDS             61808..62626
                     /locus_tag="LLC22_000259"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBK5433567.1"
                     /translation="MTKLSEMLQETTQFILDKGVKEIDFGLILGSGLGELADEIEDAV
                     MISYDEIPFFPVSTVVGHAGKLVYGSLAGKKVLAMQGRFHYYEGHSMQTVTYPVRVMA
                     GLGAHSVIVTNACGGVNESFVPGDLMLITDHINFTGENPLIGPNEDAMGPRFPDMSQA
                     YTPDYQATAKAAAEKLGLDLKEGVYMGYSGPTYETPAEIRMSRTIGADAVGMSTVPEV
                     IVAAHSGLKVLGISCITNLAAGMQANLSHEEVVETTQRVKQSFKALVKETLTLL"
     gene            62643..63350
                     /gene="deoD"
                     /locus_tag="LLC22_000260"
     CDS             62643..63350
                     /gene="deoD"
                     /locus_tag="LLC22_000260"
                     /EC_number="2.4.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine-nucleoside phosphorylase"
                     /protein_id="HBK5433568.1"
                     /translation="MSVHIEAKEGEIADKILLPGDPLRAKYIAETFLEDPVCYNQVRG
                     MLGFTGKYKGERISVQGTGMGMPSATIYAHELIQSYGVKKLIRVGTCGALSKDVHVRD
                     LVLAQGAATSSSMIEKNFQAFHFPPISDFNLLLKAYEIAKEKGYTVHVGNVLSEDSFY
                     KDDLTETFQLAELGVLGVEMEAAALYYLGAKYHVQTLSLMTVSDHLITGEETTAAERQ
                     STFNEMIEVGLETAIAE"
     gene            complement(63648..64334)
                     /gene="gpmA"
                     /locus_tag="LLC22_000261"
     CDS             complement(63648..64334)
                     /gene="gpmA"
                     /locus_tag="LLC22_000261"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-diphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBK5433569.1"
                     /translation="MPKLVFSRHGLSEWNALNQFTGWADVNLAPEGIEEAKEGGRKIK
                     EAGIEFDVAYTSVLTRAIKTCNLILEYSDQLWVPQIKSWRLNERHYGKLQGLNKKETA
                     EKYGDEQVHIWRRSYDTLPPLMEETDEGSAANDRRYAMLDKRDIPGGENLKVTLERAL
                     PFWQDEIAPALLDNKTVLVAAHGNSLRALAKHIEGISDEDIMDLEIPTGQPLVYELND
                     DLTVAKKYYL"
     gene            complement(64506..65087)
                     /locus_tag="LLC22_000262"
     CDS             complement(64506..65087)
                     /locus_tag="LLC22_000262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5433570.1"
                     /translation="MKIIGYARTTINDVDLTTQVDQLSDFGCQEIFHETYEVEQNDST
                     AVHLESVIADMQQGDALVICQLHRLGKSTRQLTELTQLFKDRGLHLISLDEGIDTREM
                     GKIYFQLMENLANMECALIKERTLVGLDEARKKGKIGGRPKIDAKTIKKIRRLYYEKK
                     ETIQFISSKCGVSVGTCYKYINLPEKEIEQLCI"
     gene            complement(65220..65903)
                     /gene="rpiA"
                     /locus_tag="LLC22_000263"
     CDS             complement(65220..65903)
                     /gene="rpiA"
                     /locus_tag="LLC22_000263"
                     /EC_number="5.3.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-5-phosphate isomerase RpiA"
                     /protein_id="HBK5433571.1"
                     /translation="MNLKQLAGIEAAKFVKDGMIVGLGTGSTAYYMVEEIGRRMREEG
                     LRITGVTTSNATKEQAEKLGIPLKSIDEVPVVDLTIDGADEISADFQGIKGGGAALLF
                     EKIVATYSKETIWIVDSSKLVDKLGKFPLPVEVIPYGSQQLLHIFEEKRFQPVLRTDE
                     NGEVLTTDGGHYIIDLHLEVIEQPESLATYLDELVGVVEHGLFLNMVSKVVVGSEKGV
                     EILDAIRRK"
     gene            66222..66635
                     /gene="rpsL"
                     /locus_tag="LLC22_000264"
     CDS             66222..66635
                     /gene="rpsL"
                     /locus_tag="LLC22_000264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S12"
                     /protein_id="HBK5433572.1"
                     /translation="MPTINQLVRKPRKSKVEKSNSPALNKGYNSFKKTQTNVNSPQKR
                     GVATRVGTMTPKKPNSALRKYARVRLSNLIEVTAYIPGIGHNLQEHSVVLLRGGRVKD
                     LPGVRYHIVRGALDTAGVNDRKQSRSKYGTKKPKA"
     gene            66719..67189
                     /gene="rpsG"
                     /locus_tag="LLC22_000265"
     CDS             66719..67189
                     /gene="rpsG"
                     /locus_tag="LLC22_000265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S7"
                     /protein_id="HBK5433573.1"
                     /translation="MPRKGPVAKRDVLPDPIYNSKLVTRLINRVMVDGKRGIAANIIY
                     NAFDLIKESTGNDPLEVFEQAMKNVQPVLEVKARRVGGSNYQVPVEVRPERRVTLGLR
                     WVVNYARLRGEHTMEERLAKEIMDAANNTGASVKKREDTHKMADANRAFAHYRW"
     gene            67283..69370
                     /gene="fusA"
                     /locus_tag="LLC22_000266"
     CDS             67283..69370
                     /gene="fusA"
                     /locus_tag="LLC22_000266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294317.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G"
                     /protein_id="HBK5433574.1"
                     /translation="MTREFSLQNTRNIGIMAHIDAGKTTATERILYYTGKIHKIGETH
                     EGASQMDWMEQEQERGITITSAATTAQWKGHRINIIDTPGHVDFTVEVERSLRVLDGA
                     VTVLDAQSGVEPQTETVWRQATTYGVPRIVFANKMDKIGADFLYSVSTLHDRLQANAH
                     PIQLPIGAEDDFTGIIDLVTMKAEMYTNDLGTEIEETEIPEEYRELAEEWREKLVEAV
                     AETDEELTLKYLEGEEITEAELKEGIRRATVNVEFYPVLCGSAFKNKGVQLLLDAVLD
                     YLPSPLDIPAIKGIDPKTDEEVERPADDSAPFSALAFKVMTDPFVGRLTFFRVYSGVL
                     QSGSYVQNATKGKRERVGRILQMHANSRSEISEVYAGDIAAAVGLKDTTTGDTLCDEK
                     SLVILESMEFPEPVIQVAIEPKSKADQDKMGVALQKLSEEDPTFRAETNVETGETIIA
                     GMGELHLDIIVDRMRREFKVEANVGAPQVSYRETFRAGTQAEGKFVRQSGGKGQYGHV
                     WIEFTPNEEGAGFEFENAIVGGVVPREYIPAVETGLKDAMENGVLAGYPLVDIKAKLY
                     DGSYHDVDSNETAFRVAASMALRAAAKKANPVILEPIMAVEVVIPEDYLGDVMGHVTA
                     RRGRVEGMEARAGGQQVVRAMVPLAEMFGYATTLRSATQGRGTFTMTFDHYEDVPKSV
                     QEEIIKKNGGKAE"
     gene            69542..70729
                     /gene="tuf"
                     /locus_tag="LLC22_000267"
     CDS             69542..70729
                     /gene="tuf"
                     /locus_tag="LLC22_000267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBK5433575.1"
                     /translation="MAKEKFDRSKPHVNIGTIGHVDHGKTTLTAAITTVLSKKNGGQA
                     MAYDQIDGAPEERERGITISTAHVEYETDTRHYAHVDCPGHADYVKNMITGAAQMDGA
                     ILVVSAADGPMPQTREHILLSRQVGVPYIVVFLNKVDMVDDEELLELVEMEVRDLLTE
                     YEFPGDDVPVVAGSALKALEGDASYEEKILELMAAVDEYIPTPERDNDKPFMMPVEDV
                     FSITGRGTVATGRVERGQVRVGDEVEVVGIAEETSKTTVTGVEMFRKLLDYAEAGDNI
                     GALLRGVAREDIQRGQVLAKPGTITPHTKFSAEVYVLTKEEGGRHTPFFTNYRPQFYF
                     RTTDVTGVVELPEGTEMVMPGDNVTMEVELIHPIAIENGTKFSIREGGRTVGAGVVTE
                     IKA"
     gene            71136..71444
                     /gene="rpsJ"
                     /locus_tag="LLC22_000268"
     CDS             71136..71444
                     /gene="rpsJ"
                     /locus_tag="LLC22_000268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003046044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S10"
                     /protein_id="HBK5433576.1"
                     /translation="MAKQKIRIRLKAYEHRILDQSADKIVETAKRTGASVSGPIPLPT
                     ERSLYTIIRATHKYKDSREQFEMRTHKRLIDIVNPTPKTVDALMKLDLPSGVNIEIKL
                     "
     gene            71475..72104
                     /gene="rplC"
                     /locus_tag="LLC22_000269"
     CDS             71475..72104
                     /gene="rplC"
                     /locus_tag="LLC22_000269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L3"
                     /protein_id="HBK5433577.1"
                     /translation="MTKGILGKKVGMTQIFTESGELIPVTVVEATPNVVLQVKTMETD
                     GYEAIQVGYQDMREVLSNKPAKGHVAKANTAPKRFIREFKNVELGEYEVGKEITVDVF
                     QAGDIIDVTGTTKGKGFQGVIKRHGQSRGPMAHGSRYHRRPGSMGPVAPNRVFKNKRL
                     AGRMGGNRVTIQNLEVVRVDAERNVILIKGNVPGAKKSLITIKSAVKAK"
     gene            72132..72755
                     /gene="rplD"
                     /locus_tag="LLC22_000270"
     CDS             72132..72755
                     /gene="rplD"
                     /locus_tag="LLC22_000270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L4"
                     /protein_id="HBK5433578.1"
                     /translation="MPNVALFKQDGSQNGEITLNEEIFGIEPNESVVYDAIVMQRASL
                     RQGTHAVKNRSAVRGGGRKPWRQKGTGRARQGSIRSPQWRGGGVVFGPTPRSYSYKLP
                     KKVRRLAMKSVLSEKVAENNLVAIEGLNFDAPKTKEFKQVLANLSIDSKVLVVLEKGN
                     DFAALSARNLPNVSVVTSDNVSVLDVVSNTKVLATQTALTQIEEVLA"
     gene            72755..73045
                     /gene="rplW"
                     /locus_tag="LLC22_000271"
     CDS             72755..73045
                     /gene="rplW"
                     /locus_tag="LLC22_000271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L23"
                     /protein_id="HBK5433579.1"
                     /translation="MNLLDVIKRPVITEKSMLAMDDKKYTFEVDTRANKTLVKQAVEA
                     AFDVKVKNVNIVNVRAKFKRMGKYAGYTKKRRKAIVTLTEDSKEIQLFEAAE"
     gene            73084..73917
                     /gene="rplB"
                     /locus_tag="LLC22_000272"
     CDS             73084..73917
                     /gene="rplB"
                     /locus_tag="LLC22_000272"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010756442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L2"
                     /protein_id="HBK5433580.1"
                     /translation="MAIKKYKPTSNGRRNMTGSDFAEITTSTPEKSLLQPLKNHAGRN
                     NNGRITVRHQGGGHKRQYRVIDFKRNKDNVVATVQTIEYDPNRSANIALVHYEDGVKA
                     YILAPKGLEVGMKLVSGPEADIKVGNALPLENIPVGTVIHNIEMKPGKGGQLIRSAGT
                     SAQVLGKEGKYVLIRLNSGEVRMILAACRATIGSVGNEQHELINIGKAGRSRWMRKRP
                     TVRGSVMNPNDHPHGGGEGKAPIGRKAPVSPWGQPALGYKTRNKKAKSDKLIVRRRKN
                     K"
     gene            73960..74238
                     /gene="rpsS"
                     /locus_tag="LLC22_000273"
     CDS             73960..74238
                     /gene="rpsS"
                     /locus_tag="LLC22_000273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000533765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S19"
                     /protein_id="HBK5433581.1"
                     /translation="MGRSLKKGPFVDEHLMKKVEAQAGVEKKKVIKTWSRRSTVFPSF
                     VGYTIAVYDGRKHVPVYIQEDMVGHKLGEFAPTRTYRGHAADDKKTKR"
     gene            74261..74608
                     /gene="rplV"
                     /locus_tag="LLC22_000274"
     CDS             74261..74608
                     /gene="rplV"
                     /locus_tag="LLC22_000274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003701308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L22"
                     /protein_id="HBK5433582.1"
                     /translation="MAEQITSAKATAKTVRTSPRKARLVIDLIRGKSVADAISILKFT
                     PNKSAGIIEKVLMSAVANAENNFDLDVENLVVSEAFVNEGPTMKRFRPRAKGSASPIN
                     KRTSHITVVVSEK"
     gene            74622..75278
                     /gene="rpsC"
                     /locus_tag="LLC22_000275"
     CDS             74622..75278
                     /gene="rpsC"
                     /locus_tag="LLC22_000275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000529931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S3"
                     /protein_id="HBK5433583.1"
                     /translation="MGQKVHPIGMRVGIIRDWDAKWYAEKEYAEFLHEDLRIRKFIST
                     KLADAAVSTVEIERATGRVNISIHTAKPGMVIGKGGSEVESLRKELNKLTGKRIHINI
                     VEIKKPDLDAKLVGEGIARQLENRVAFRRAQKQAIQRSMRAGAQGIKTQVSGRLNGAD
                     IARSEGYSEGTVPLHTLRADIDYAWEEADTTYGKLGVKVWIYRGEILPTKKNTEKGGK
                     "
     gene            75281..75715
                     /gene="rplP"
                     /locus_tag="LLC22_000276"
     CDS             75281..75715
                     /gene="rplP"
                     /locus_tag="LLC22_000276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L16"
                     /protein_id="HBK5433584.1"
                     /translation="MLVPKRVKHRREFRGKMRGEAKGGKEVAFGEYGLQAVDSHWITN
                     RQIEAARIAMTRYMKRGGKVWIKIFPHKSYTAKAIGVRMGSGKGAPEGWVAPVKRGKI
                     MFEIAGVPEEVAREALRLASHKLPMKTKIVKREEMGGESNEG"
     gene            75705..75893
                     /gene="rpmC"
                     /locus_tag="LLC22_000277"
     CDS             75705..75893
                     /gene="rpmC"
                     /locus_tag="LLC22_000277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288664.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L29"
                     /protein_id="HBK5433585.1"
                     /translation="MKVKEIRELTTAEMLDQEKQLKEELFNLRFQLATGQLENTARIK
                     EVRKSIARIKTVLREQAK"
     gene            75918..76184
                     /gene="rpsQ"
                     /locus_tag="LLC22_000278"
     CDS             75918..76184
                     /gene="rpsQ"
                     /locus_tag="LLC22_000278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S17"
                     /protein_id="HBK5433586.1"
                     /translation="MTEGRNQRKVYQGRVVSDKMDKTITVAVETKKNHPIYGKRMNYS
                     KKYKVHDENNTAKVGDIVRIMETRPLSATKRFRLLEVVEEAVII"
     gene            76242..76610
                     /gene="rplN"
                     /locus_tag="LLC22_000279"
     CDS             76242..76610
                     /gene="rplN"
                     /locus_tag="LLC22_000279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012727667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L14"
                     /protein_id="HBK5433587.1"
                     /translation="MIQAESRLKVADNSGAREILTIKVLGGSGRKTANIGDVIVATVK
                     QATPGGVVKKGDVVKAVIVRTKSGARRTDGSYIKFDENAAVIIRDDKSPRGTRIFGPV
                     ARELRENNFMKIVSLAPEVL"
     gene            76647..76955
                     /gene="rplX"
                     /locus_tag="LLC22_000280"
     CDS             76647..76955
                     /gene="rplX"
                     /locus_tag="LLC22_000280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L24"
                     /protein_id="HBK5433588.1"
                     /translation="MFVKKGDKVKVITGKDKNKEGVVLAAFPKKDKVIVEGVNVVKKH
                     QKPSQAAPQGGIVEMEAPIHVSNVMVVDSTGVAGRVGYKEVDGKKVRVSKKTGEVLDK
                     "
     gene            76983..77522
                     /gene="rplE"
                     /locus_tag="LLC22_000281"
     CDS             76983..77522
                     /gene="rplE"
                     /locus_tag="LLC22_000281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_466143.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L5"
                     /protein_id="HBK5433589.1"
                     /translation="MNRLKEKYLKEVTPSLMEKFNYSSVMQTPKVEKIVINMGVGDAV
                     SNAKNLDKAVEELTLITGQKPMITKAKKSIAGFRLREGMPIGAKVTLRGERMYEFLDK
                     LVSVSLPRVRDFHGVSKKAFDGRGNYTLGIKEQLIFPEVDYDLVDKVRGMDIVIVTTA
                     NSDEESRELLTQLGMPFQK"
     gene            77541..77726
                     /locus_tag="LLC22_000282"
     CDS             77541..77726
                     /locus_tag="LLC22_000282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011245027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type Z 30S ribosomal protein S14"
                     /protein_id="HBK5433590.1"
                     /translation="MAKKSMIAKNKRPAKFSTQAYTRCERCGRPHSVYRKFHLCRICF
                     RELAYKGQIPGVKKASW"
     gene            77762..78160
                     /gene="rpsH"
                     /locus_tag="LLC22_000283"
     CDS             77762..78160
                     /gene="rpsH"
                     /locus_tag="LLC22_000283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010742763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S8"
                     /protein_id="HBK5433591.1"
                     /translation="MVMTDPIADFLTRIRNANMVKHESLEVPASKIKRDIAEILKREG
                     FVRDVEYIEDDKQGVIRVFLKFGKNGERVITNLKRISKPGLRAYVKADEVPKVLNGLG
                     IAIISTSEGVVTDKEAREKNIGGEVIAYVW"
     gene            78192..78728
                     /gene="rplF"
                     /locus_tag="LLC22_000284"
     CDS             78192..78728
                     /gene="rplF"
                     /locus_tag="LLC22_000284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L6"
                     /protein_id="HBK5433592.1"
                     /translation="MSRIGNKVVVIPEGVTVTQDGNNVTVKGPKGELTRTFSADIKMN
                     IEGNEVTFTRPNDSKEMKTIHGTTRANFNNMVVGVSEGFQKALELIGVGYRAQLQGSK
                     LVLNVGYSHPVEITPPAGVTVEVPANTQVIVKGANKEEVGELAANIRGTRPPEPYKGK
                     GIRYVGEYVRRKEGKTGK"
     gene            78889..79245
                     /gene="rplR"
                     /locus_tag="LLC22_000285"
     CDS             78889..79245
                     /gene="rplR"
                     /locus_tag="LLC22_000285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000628816.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L18"
                     /protein_id="HBK5433593.1"
                     /translation="MITKPDKNKTRQKRHRRVRNNISGTAERPRLNVFRSNKNIYAQI
                     IDDVAGVTLASASTLDKEISGGTKTEAAQAVGKLVAERAAEKGIKVVVFDRGGYLYHG
                     RVQALAEAARENGLEF"
     gene            79266..79766
                     /gene="rpsE"
                     /locus_tag="LLC22_000286"
     CDS             79266..79766
                     /gene="rpsE"
                     /locus_tag="LLC22_000286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288681.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S5"
                     /protein_id="HBK5433594.1"
                     /translation="MVYIDPKHLELEDRVVAINRVTKVVKGGRRLRFAALVVVGDKNG
                     HVGFGTGKAQEVPEAIRKAIEDAKKNLVEVPMVGSTIPHEVIGAFSGGRILMKPAVEG
                     SGVAAGGPVRAVLELAGVADITSKSLGSNTPINVVRATVEGLKQLKRAEEVAELRGKS
                     VEELIG"
     gene            79781..79960
                     /gene="rpmD"
                     /locus_tag="LLC22_000287"
     CDS             79781..79960
                     /gene="rpmD"
                     /locus_tag="LLC22_000287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L30"
                     /protein_id="HBK5433595.1"
                     /translation="MAELKVTLKRSIIGRPQNQRDTVKALGLTKINSSVVKPSNEAIK
                     GMINTVSHLVDVEEI"
     gene            80004..80444
                     /gene="rplO"
                     /locus_tag="LLC22_000288"
     CDS             80004..80444
                     /gene="rplO"
                     /locus_tag="LLC22_000288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005592004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L15"
                     /protein_id="HBK5433596.1"
                     /translation="MKLHELKPAEGSRQVRNRVGRGTSSGNGKTAGRGQKGQKARSGG
                     GVRLGFEGGQTPLFRRLPKRGFTNVNRKDYAVINLDVLNRFEDGAEVTPVALVEAGIV
                     KNEKAGIKVLANGELNKKLTVKAAKFSKAAQEAIEAAGGSIEVI"
     gene            80444..81739
                     /gene="secY"
                     /locus_tag="LLC22_000289"
     CDS             80444..81739
                     /gene="secY"
                     /locus_tag="LLC22_000289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345495.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecY"
                     /protein_id="HBK5433597.1"
                     /translation="MFRLLKDAFKVKDIRSKILFTVFVLFVFRLGAHITVPGVNAASL
                     QNLSSLPFFNMLNLVSGSAMQNFSIFSMGVSPYITASIVIQLLQMDIVPRFVEWSKQG
                     EVGRKKLNQATRYLTLVLAFIQSVGITAGFNQYAQLGFVNNPNVATYVTIGLILTAGT
                     MFVTWLGEQITEKGIGNGVSMIIFAGIISRLPESIREIYEDYFINIDPSDIWKSAIFV
                     AILLVAVLLIVTFVTFFQQAERKIPIQYTKRVAGAPTSSYLPLKVNAAGVIPVIFASS
                     FIATPNAVLQALSGRFGSENWYKVMMEIFNYNTAPGATIYTILIVAFTFFYAFVQVNP
                     EKLAENLQKQGSYIPSVRPGKGTEEYVSRLLMRLSTVGAVFLGLVALLPIIAQMVWDL
                     PQSIGLGGTSLLIVIGVALETAKQLEGLMLKRKYVGFIE"
     gene            81801..82448
                     /locus_tag="LLC22_000290"
     CDS             81801..82448
                     /locus_tag="LLC22_000290"
                     /EC_number="2.7.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylate kinase"
                     /protein_id="HBK5433598.1"
                     /translation="MNLILMGLPGAGKGTQAEKIIDAYGIPHISTGDMFRAAMQNETA
                     LGLEAKSYMDKGALVPDEVTNGIVKERLAEPDTEKGFLLDGFPRTLDQAKALDAMLKD
                     LNKKIDAVIDIHVGEEILVERLAGRFICSNCGATYHKIFNPTKVEDTCDRCGGHEFYQ
                     REDDKPETVKNRLAINIKNSEPILAYYKEQGLLNTIDGAREIDAVFADVQKIIEK"
     gene            82639..82857
                     /gene="infA"
                     /locus_tag="LLC22_000291"
     CDS             82639..82857
                     /gene="infA"
                     /locus_tag="LLC22_000291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-1"
                     /protein_id="HBK5433599.1"
                     /translation="MAKEDMIEVEGTVVETLPNAMFKVELENGHQVLATVSGKIRMHY
                     IRILPGDKVTVELSPYDLNRGRITYRFK"
     gene            82890..83006
                     /gene="rpmJ"
                     /locus_tag="LLC22_000292"
     CDS             82890..83006
                     /gene="rpmJ"
                     /locus_tag="LLC22_000292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003720928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L36"
                     /protein_id="HBK5433600.1"
                     /translation="MKVRPSVKPMCEHCKVIRRKGRVMVICPANPKHKQRQG"
     gene            83024..83389
                     /gene="rpsM"
                     /locus_tag="LLC22_000293"
     CDS             83024..83389
                     /gene="rpsM"
                     /locus_tag="LLC22_000293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008809894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S13"
                     /protein_id="HBK5433601.1"
                     /translation="MARIAGVDIPRDKRVVVSLTYIYGIGNTTAKKILADAGVSEDVR
                     VRELTNEQTDAIRAEVDKLKVEGDLRREVNLNIKRLMEIGSYRGIRHRRGLPVRGQNT
                     KNNARTRKGPARAIAGKKK"
     gene            83417..83806
                     /gene="rpsK"
                     /locus_tag="LLC22_000294"
     CDS             83417..83806
                     /gene="rpsK"
                     /locus_tag="LLC22_000294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S11"
                     /protein_id="HBK5433602.1"
                     /translation="MAAKKVNRKRRVKKNIEAGIAHIHSTFNNTIIMITDTHGNALAW
                     SSAGSLGFKGSKKSTPFAAQMAAETATKAAMEHGLKTVEVTVKGPGSGREAAIRSLQA
                     TGLEVTAIRDVTPVPHNGARPPKRRRV"
     gene            83886..84824
                     /locus_tag="LLC22_000295"
     CDS             83886..84824
                     /locus_tag="LLC22_000295"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010774253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit alpha"
                     /protein_id="HBK5433603.1"
                     /translation="MIEFEKPRIAKIDEEKDYGKFIVEPLERGYGTTLGNSLRRILLS
                     SLPGAAITNIQIDGVLHEFSTIKGVREDVTQIILNIKGLALKMYGQEEKTLEIDITGP
                     ATVTAGDIIVDSDVEILNKDMYICSVSEGATFHARLTVKPGRGYVQADENKKEDMPIG
                     VLPVDSIYTPVRRVNYQVENTRVGHREDFDKLTMEIWTDGSIEPLEAMSLSAKIMTEH
                     LDIFVNLTDEAKNAEIMVEKEETQKEKMLEMTIEELDLSVRSYNCLKRAGINTVQELT
                     NKSEPEMIKVRNLGRKSLEEVKAKLHDLGLGLRKED"
     gene            84852..85232
                     /gene="rplQ"
                     /locus_tag="LLC22_000296"
     CDS             84852..85232
                     /gene="rplQ"
                     /locus_tag="LLC22_000296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L17"
                     /protein_id="HBK5433604.1"
                     /translation="MSYRKLGRTSSQRKAMLRDLTTDLLINERIVTTEARAKEVRSTA
                     EKMITLGKRGDLHARRQAAAFVRNEVASVREENEDIVIESALQKLFNDIAPRYAERQG
                     GYTRILKTEPRRGDGAPMVVLELV"
     gene            85504..86343
                     /locus_tag="LLC22_000297"
     CDS             85504..86343
                     /locus_tag="LLC22_000297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5433605.1"
                     /translation="MEPIIELEKINYKYQPDDLRPALKDVSFTIDKGEWIAIIGHNGS
                     GKSTLAKTINGLLLPESGIVKVGNQILDEENIWTIRQMVGMVFQNPDNQFVGSTVEDD
                     VAFGLENQGIPREEMLVRVKDALEKVRMAEFASREPARLSGGQKQRVAIAGVVALRPD
                     IIILDEATSMLDPEGREEVISTIKKIKEESQLTVISITHDIDEAANANRILVMRQGEL
                     VREGTPKEIFSAGPELIDLGLDLPFPEKLKSALKERGVDVPSEYMTEERMVDWLWTSV
                     LNK"
     gene            86319..87188
                     /locus_tag="LLC22_000298"
     CDS             86319..87188
                     /locus_tag="LLC22_000298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5433606.1"
                     /translation="MDIRFEQVDFTYQPNTPFEQRALFDINMTIKENSYTALVGHTGS
                     GKSTLLQHLNALVKPTSGTVHIGERDIQPDTDNKNLKPIRKKVGIVFQFPEAQLFEET
                     VAKDIAFGPKNFGVSEEEALVLAKETLEQVGLDESYLERSPFELSGGQMRRVAIAGVL
                     AMRPEVLVLDEPTAGLDPQGRKEMMEMFWRLHKEQQITIVLVTHLMDDVANFADYVYV
                     LEKGRIVNSGEPQEVFQNIEWLKEKQLGVPTATEFAEELMAKGMNFATLPLTAEELAD
                     AIVHYAGGNAHDE"
     gene            87178..87975
                     /locus_tag="LLC22_000299"
     CDS             87178..87975
                     /locus_tag="LLC22_000299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
                     /protein_id="HBK5433607.1"
                     /translation="MMNKLIFGRYMPGDSLIHRLDPRAKLLASFYFIGIIFLANNWET
                     YLLLAFFTLLSVFLSKVDLKFFIRGIRPLIWLILFTVALQVLFTSGGETYWSWGVFHI
                     TEFGVMNGLFIFCRFVLIIFMSTLLTLTTPPLELSDAIEYLLRPLKAVRFPVHEISLM
                     LSIALRFVPTLMDETEKIMNAQRARGVDFGEGNLVQKMKAVIPLLIPLFVSSFNRAED
                     LATAMEARGYKGGEGRTKYRVLHWHNRDTMVIIAFVLLTVLLIFLRG"
     gene            88178..88924
                     /gene="truA"
                     /locus_tag="LLC22_000300"
     CDS             88178..88924
                     /gene="truA"
                     /locus_tag="LLC22_000300"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBK5433608.1"
                     /translation="MVRYKAIIAYDGTNFNGFQKQPNGRTVQEEVEKTLQKMANGKEI
                     TVFGSGRTDAGVHAIGQVIHFDYPEERPLERMRFALDTQSPEDIAVRQVEIVSEDFHA
                     RYLVKEKTYQFRVDIGKPRSPFRRHYASYFPYPLDLEKIQRALPDLLGTHDFTSFCAS
                     GSSIEDKIRTIYEAKMEVNETKDELLFTFRGNGFLYKMIRILVGTLLKIGNGRLPEDS
                     IPDIIAKKDRNAAGPTAHPEGLYLYEVKYE"
     gene            complement(89257..91926)
                     /locus_tag="LLC22_000301"
     CDS             complement(89257..91926)
                     /locus_tag="LLC22_000301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfhO family protein"
                     /protein_id="HBK5433609.1"
                     /translation="MKKNLKSFFRENGRYAAASFLIPFLILALVYLSIGIYPGSSRSI
                     LASDAFSQFSNFHASFRNVLLGKQSIFYTWNASLGLNYLSLISYYLGGIFTPLVFFFP
                     NQMMPDALYVLTLLKVGCAGLAFWFLARTFKIPRWGHVALSVSYALISFITAHSEIIM
                     WLDAFVYLPLVILGIHRVMDLKRPKLLFISYLLLFLSSFYMGFMIGVFSFLYFIARLL
                     TNWSEYKKTIVPYGITSLLAGGASMIIVLPAVLDLRSNGEALSQITTLKTEATSYLDL
                     IMKNMIGVYDTTKYGSIPFVYAGLLPLVLCLFYFASRKVPLKNKFLYGSLFAILIASF
                     YLVPLNLFWHGMHAPNMFLFRYAYLFSFLVLLLAGKGWEKIEQDDRGLLLGIILVVAA
                     LFAVAWGIKPEGSYTYVTMTSFVLTVVFLGIYAFAVGFYQHKKLSFNHLSILLLLIMS
                     AEALVNTNSMIHGILDDWNYASRSLYTDPYPDLKALVNETKKDSDSFYRLENLDPVSA
                     NDSINYGYSGISLFSSIRNRNSSSYLDKLGFRSRGTNLNIRYNNNTLLMDGFTGIKYN
                     ISKNESTFSKYGFRQAGQSGDYTLYQNVNALPLAFTAPLSVNDVEQPVTDNLTSQTNL
                     INTLSGLNEQYFTFYTPTLKNQLNTTITKTTTGVTYSETADNQPKELTWEVHVPANTQ
                     AYLSLFPTNFAQLESSSATITVNGTSRKTQINISGQYYDLGYYPQETTVTFTASFYGT
                     KEISFMEPKVVGLDVVAYQAAMNQIKEKGVEMEATGRKASGTVNTAEDSMLVTTIPYD
                     KGWKAKIDGKPVKVSNFKDAFLMIKVPAGKHTVTFSYLPEGFTIGAILFVLCIALFIL
                     YVWYLDRNRPFYGTIDPAIEEQPRNTHRRRRRK"
     gene            complement(92164..92352)
                     /locus_tag="LLC22_000302"
     CDS             complement(92164..92352)
                     /locus_tag="LLC22_000302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L28"
                     /protein_id="HBK5433610.1"
                     /translation="MAKVCYFTGRKTKSGNNRSHAMNSTKRTVKPNLQKVRVMVDGKP
                     KKVWVSTRALKSGKVERV"
     gene            92622..92984
                     /locus_tag="LLC22_000303"
     CDS             92622..92984
                     /locus_tag="LLC22_000303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5433611.1"
                     /translation="MAVKIQTSAGTIEITNDVIATVVGGAATDVFGVVGMASKNQIKD
                     NITEILRKENYSRGVVVRQEDNGIAVDVYTIISYGTKISEVSRNVQEKVKYNLEALLG
                     VTANSVNVFVQGVRVLPD"
     gene            93036..94718
                     /locus_tag="LLC22_000304"
     CDS             93036..94718
                     /locus_tag="LLC22_000304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DAK2 domain-containing protein"
                     /protein_id="HBK5433612.1"
                     /translation="MSVTEISASQFQEMVQAGANRLQVNAEYVNSLNVFPVPDGDTGT
                     NMNLSMTSGAKAVVDSTSEKVGELAAMLSKGLLMGARGNSGVILSQLFRGFSKQIPDV
                     VSLNASDLAAAFTHGVETAYKAVMKPVEGTILTVAREAAKAGEKKAKSTDDVVEVMTA
                     VVKGAKRALAKTPDLLPVLKEVGVVDSGGQGLLFVYEGFLSALNGEFQADETYEPSPA
                     EMDDMVNAEHHRSVQGQMATEDIHFGYCTEIMVKIGEGPTVDSTFDYEEFRNYLDGIG
                     DSLLVVNDDEIIKVHVHTENPGEVLNYGQKFGSLVKIKVDNMRLQHETILEHDEEVNE
                     FAKKEIPRIPYGIVAIAAGKGVQELFESLGANYVISGGQTMNPSTEDIVKAIQEVNAD
                     KVIVLPNNKNIFMAADQAAEVADIPVAVVPSRTISQGLTAMLSFNDQASLEENKETMT
                     EMLSSVVSGQVTHAIRDTSIDGVEIKEGDFLGMIDGKILISNPDITATALSTLEQMIN
                     EDTEIVTILAGDEGTVEQANEFAEKLTEKHPDLEIEIHQGDQPVYPYLFSAE"
     gene            94835..96871
                     /gene="recG"
                     /locus_tag="LLC22_000305"
     CDS             94835..96871
                     /gene="recG"
                     /locus_tag="LLC22_000305"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecG"
                     /protein_id="HBK5433613.1"
                     /translation="MRSLDDPITMLAGVGEKRAASLASLGIQTIEDLLTYYPFRYEDI
                     QERNLNEIQDQEKVTLKGIVVSPPVMNRFGYKKSRLQFRMMQEHDVFNVSFFNQPYLK
                     EKVILSEEIAVYGKWDAKRKALNGMKILGSQTMDDFSPIYHVNKSIRQTTLVDLIKKG
                     FQEYGTLIEENLPNNLVEKYRLLDRASAVRSMHFPKDHEENHQAKRRVVFEEFFLFQM
                     RLQGLKKAEKAETNGLEILYDVQKLKQFTQKLPFELTNAQKRVTNEICRDLRSPQHMQ
                     RLLQGDVGSGKTVVAAIALYATVTAGFQGALMVPTEILAQQHMESLQQLFDPNEVTIA
                     LITGSTKAKERRELLEKLEQGEINVVIGTHALIQDGVEFQNLGLVITDEQHRFGVNQR
                     KVLREKGWRPDVLFMTATPIPRTLAITAYGEMDVSIIDELPAGRIPIETRWVRTPQLD
                     SVLDWTKKELARGHQMYVICPLIEESEALDVKNAVEIYEKLRELFAPKYEVGLLHGKM
                     KNQEKEVIMEAFKDNQMQILVSTTVIEVGVNVPNATVMLIMDADRFGLAQLHQLRGRV
                     GRGSDASYCILVANPKNELGVERMKIMTETTNGFVLSEKDLELRGPGEVFGFRQSGLP
                     QFAIADLVTDGNVLEVAREEAAALWQIKDWQMLPEYQPLAQSLQIENQDNRYFD"
     gene            96920..97921
                     /gene="plsX"
                     /locus_tag="LLC22_000306"
     CDS             96920..97921
                     /gene="plsX"
                     /locus_tag="LLC22_000306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acyltransferase PlsX"
                     /protein_id="HBK5433614.1"
                     /translation="MKIAVDAMGGDHAPQAIVEGVALAQQDFPEVEFLLYGKEAEIKK
                     YLTNEKNITIIHTDEKINSDDEPVKAIRRKKTASMVLAAQAVKNGEADAVFSAGNTGA
                     LLAAGLFIVGRIKNIERPGLMSTLPVVGKEGAGFDMLDLGANAENKPEHLLQYGILGS
                     FYARKVRGIGRPRVALLNNGTEATKGSEVTKKAYELLQNETSLNFIGNVEARELLNGV
                     ADVVVTDGFTGNAVLKSIEGTAMNMMNLLKSAILNEGIKGKMGAMLLKDGLRSLKAEM
                     DYSKHGGAVLFGLKAPVIKTHGATGPDAVRYTIRQIHTMLETDVVGQLVEQFEKSEE"
     gene            98043..98285
                     /gene="acpP"
                     /locus_tag="LLC22_000307"
     CDS             98043..98285
                     /gene="acpP"
                     /locus_tag="LLC22_000307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBK5433615.1"
                     /translation="MTREEVFNKVAKIISNHFEIDTDKVTDELNIKDDLKADSISIME
                     FVLELEDEFGTEISDEDAEQIETVGGAVDYISSHLK"
BASE COUNT        32074 a        17203 c        20399 g        28757 t
ORIGIN      
        1 ccactaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatt caacaaacat
       61 gagaagctgt tttttgaaat tgttccttgt gactcggagc taaacggcag gctcacaacc
      121 tcttggtaaa cggtgttcaa tcagctgacc ctcggtatta gctcaaaaaa cggcaaaata
      181 tgaggaacta ttttttccgt ttttttctct aatactcagg tcaaaacgct gatttcacaa
      241 cctctgattc acggtgttcc agaagtagct tctacggaaa taagccgaaa tttcacaaaa
      301 atttgagaag caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac
      361 aacctcttat tttgattaga acttgcgaaa ataaaccggt taaagtgtgt ctagcgcaag
      421 agatttgcta taatagacga taagggtaaa atgtaacgag aaggggttga aaaatgtgta
      481 tcaaattgta acagattctt gttgtgatct gccataccat gtattagcaa aagaaaaagt
      541 tgatttttta tcaatgaatc tccaattgaa tgatcaagag ttagtagatg acctcggaaa
      601 gacattcaat tatgaccgct acatgaatca gctgaaaaat ggtgcgatgc ctacgacatc
      661 acaaatcaat gttggccgat atttagaatt tttccgttct tatgcggaaa aacagattcc
      721 tgttttatat gtggcttttt ccagtggatt aagcggctct tacagtagtg cgcttcaagc
      781 ggttgaattg ctgaaggaag aatatgaaga ccctgagatc tatgtttttg atacaaaagc
      841 tgcaagtatt ggggaagggc ttttagtatt ggaagctgta agattgaaaa aagaaggtaa
      901 aagcatcgaa gaaaccctag agtggctgga aagtaattat ttgaaagtcc attcatgggt
      961 aacagtagac gatctgaaat atctagaacg aggcggtagg atttccaaag caagtgctac
     1021 tcttggcagt ctattgagtg taaagcctat tattacggtg gataaagaag gaaggctgac
     1081 gaatgttgac aaagttcgag gaagaaacaa gtcgatccag acaatcgtca atgagacggt
     1141 aaaaacaatc gttgcaccac ttgatcaaat cgtttatgtg gcttacgctg gggatctaga
     1201 gagcgcggag aaggcaaaac ggcttttgga agagcagata aagatgaaag atgtgaagct
     1261 ttatccctta ggaccaacga tcgccagtca cacaggctat ggctgtatcg cgattttttc
     1321 gatgggaatc agtcgataaa agcagtaact cattctgtaa aaaagcccag aaattgattg
     1381 taacaaaaac agcgactctt aaaagataga tgagcatcct atctcttaga ggtcgctgtt
     1441 tttttatttt ttaagctaaa taggccatta tgcccataac tcgttcaatt gtttttgaat
     1501 atctgcattt tccaaaaatt catcatatgt cgtatcagct cgatcgatca cacctttatc
     1561 cgaaacggca atgatgcggt ttgccaatgt ttggataaat tgatggtcat gtgacgcaaa
     1621 taagattgag ccagtaaatg ccatcaagcc gtcattcaat gctgtgattg attctaagtc
     1681 taaatggttc gttggatcat ctaatacaag tacgttagct ttcgaaagca tcatttttga
     1741 aagcatgcaa cggactttct ctccaccaga taaaacattc actggtttca atacttcttc
     1801 accagaaaac aacattcttc ctaagaagct tcttaagaag gtgttatcat cttcttcttt
     1861 acttgcatat tgacgcaacc agtctaaaat cgttagatca gtatcgaatt ctttcgttgt
     1921 atcctttggt aaataagaat tacttgttgt cacaccccaa cgtactgttc cagtatctgg
     1981 cgtaatttca cccatgataa ctttgaatag cgttgttgtt gttatatcat tttctgcgac
     2041 gaaagcgacc ttgtcttctt tgctcaaatt aaaagatata tcatctaaaa ttttctttcc
     2101 atcaatcgtt acacttacat tttctacctg caataagtcg tttccaatct cacgttcagg
     2161 tttgaatcca acgaatggat aacgtctaga agaaggttgg atatcgtcta aagtaatttt
     2221 ttcaagcatt tttttacgtg aagttgcttg ttttgatttt gatgcattcg cactaaagcg
     2281 ggcaataaat tcttggagtt ctttgatttg ttcttctttt ttggcatttg cgtttgcttg
     2341 aagtttagcc gctagttgac tagattccaa ccaaaaatca taatttccta cataaagttt
     2401 gattttacca aaatctagat ccgccatatg tgtacatact ttgttcaaaa agtgacggtc
     2461 atgggataca acgatcacag tattttcaaa attgatcaaa aattcttcca gccaattgat
     2521 cgattggata tccagaccgt ttgttggttc gtctagcaaa agaacatcag gtttaccaaa
     2581 tagtgtttgt gctaataaca cttttacctt ttgtccacca gttaattcac tcatttgctg
     2641 atggtgcaat tcttcaggga tgttcagacc ttgcagtaaa acagctgctt ctggttcagc
     2701 ttcccatcca ttaagctcag caaattctcc ttctaattca gctgctcgaa taccatcttc
     2761 gtcagtgaaa tcctctttca tgtaaatcgc atctttttct ttcagcactt catacagacg
     2821 cttgtgtccc atgatgactg tttcaagtac agtatagtct tcatagtcgt aatggttctg
     2881 tttcaatacg gccatccgtt catctggtcc catagtaacg gaacctgtgg aaggctgcag
     2941 atcccctgat aacactttaa ggaacgttga tttacctgca ccatttgcac caatcaagcc
     3001 atagcagttt ccgggggtaa atttaatatt cacatcatca aatagtttgc ggtctgaaaa
     3061 gtgcaaactc acatcattta cagtaatcaa tttttttcct cacttttatc attattagtt
     3121 ttgacaagtc ttatagaatt atatagggga aaggtaaaag attcaaggca atcgaacatt
     3181 ctttgtgttt cacgtgaaac agaatgaaaa aaataaaaat aaaagcggag cgaaaatagc
     3241 tactatagga tttattagtt tgcaacagca taatttttga cgttatttat aagagggagt
     3301 actataaaac tgtaaaagaa atgaaagaag gattgaaaat ggatgaaaaa agaaccatcg
     3361 actggggctc attgattttg ggaattttat ttgtacttgt ctcattgtta tcatttcaag
     3421 accctgtcgg aaatttagtt gcaattgtag tagtctttgc gatttttgcc tttattaaag
     3481 ggatatttga actgtttgta cggaacagat taaaagagct aacaggatat aaaggaaaga
     3541 tgcccttaat aatcgggatc atcgatattc tagttggcgt ctttttctta ttcaatattg
     3601 gtgcaggagt cgcagcattg ccttttgttt ttgcagtatg gtttattgct gattcagttt
     3661 tagcgttatt tactgctgac ttggcaagag gagtaagtga aggatattat tggtttacga
     3721 tcatcgtcaa tattttagga attttattag gaattttctt attgtttaat ccaatttctt
     3781 ctgcgttgac attaagcttt ttagttggat tctattttat gttatttggt atcacacata
     3841 tcgtctatgc atttagataa gtaaaatcaa acaaataaaa aagccggctt ccgattacag
     3901 ttttactgtt gtaattggaa gccggctttt ttatcatgga caaatatgca cgaggtgatt
     3961 tttaggtgtc gagacaaatt tatgcaaaaa tgtgagaagc tatatacaca aattttatct
     4021 taatactcga agcatagcgc agttgtcaca acctcttttc atataattca ttcaatactg
     4081 gcaaatcatg gacttcatat ttttctttga atgcttggat ttcttcttca gaatattttc
     4141 ttggatctaa atgcagatct tctactggca atgggcgctt gttattgatc ttcacatcga
     4201 ttactacagg acgatctgat tttgcagctg catcaaaggc aaatcgaagt tgcgagtatt
     4261 ctgtgactgt aaagctattt gccccgagcg cttctccaac tttaccgaaa tctgcatctt
     4321 ctaaaaatac accaaatttc ttttgttccg tatcttcttg ttctgcttcg atgaaaccaa
     4381 aagaatcatt cgaaaagaca acattaataa ttggaagctg atatttgact tgtgtaatga
     4441 tatcttgcat gaccatagca aacccgccat caccacttaa ggtaaatact tgtttttctg
     4501 ggtagcttag ttgtgcggca attcctcctg gcacaccatt acccatagtt gcgaaccatc
     4561 cagatgtcgt atgtttttgt ttaccgttca tattcaataa acgaatagaa tggatagtcg
     4621 tgttaccgac atctgtgacg aaaatcgcat cgtcttcagc aatacgattg atttctttat
     4681 agacagcctc tggacgaatc ggttcttcct ctcgatcttc aaaagatttc aaccaattta
     4741 cccatttttc tttattttct tgatttgcta ggtaccagct atcagcaggg cgagcatccc
     4801 ctaactcgac aagtctttgc aaagctgtgt ttgcatcacc gaggatcgac aaagatgttt
     4861 catggcgtcg tccaaatttt gacgcatcga tatcgatttg gataaattca gcagttggat
     4921 taaaaaatgc acgtccaaat gggaagtcgc taccgacaaa taagatcaga tcggcttctg
     4981 ccaatgcttc atttccgggt ttagtagcga cacgtccagc aaaaccaaga aagttttcat
     5041 aatcatcagg aataattcct tttgctagaa cggaagcgac aacaggaact gaaaaatgtt
     5101 ctgagaattc tttgatttgc ggaaatccgt ttcgcgttcc ttgaccaaca taaagaactg
     5161 gtttttttgc tttttcaaga taaggcaaag cagctagcaa atctttttct tctggtaata
     5221 tcacacttgt tttgtgagtg tgagcggtgg agaaaggttg ttcgtcaatt tcttcaaaac
     5281 caagatcaac agggatagtc acgatagcca cgcctttatg ctcataggcg gctttaatgg
     5341 cttcatctac tacatgcgga agactttgtg gtgtcatgac tgtacgattg tatacgctaa
     5401 catctgcgaa aataggattt tcatttagtt cctggaaaga gttatagttc atggatgtag
     5461 aagcaacttg tcctaagaac gctactagag gcacatggtc catctgtgca tcatacaaac
     5521 cattgatcaa atgtgtcgca ccaggtcctg cagagccgaa gacagcgccg actttccccg
     5581 ttaattttgc atctgcagcg gctgcgagtg cgccgacttc ttcatgacga acttgaatgt
     5641 agttgatttc ggttttttct tgatatagcg catccataat tgaattgaaa gatcctccgg
     5701 gaatgccgta aatatggtcg ataccccagc tttcaagaac ttttaccatt gcgattcctg
     5761 cattgatttt tgacatggtg tttcactcct ttagcaatga tgatacataa attttttgta
     5821 tctagagtat agaacttttt atcgaaaatc ccaactaatt cgtcttttca caaaaatgta
     5881 gtcatgtttt tgggaatatg ctagagtagt acatagatag attcaagaga ggggaatggc
     5941 atggttgaat ggctattgag acttgaacct tggcagcaag cacttgctgg gacagctttt
     6001 acttatttta tgacagctct tggtgccggg ttggtttttt tctttaaaga aatcaaaaaa
     6061 gaagtgctaa acttgatgtt aggatttgct tctggtgtca tgattgctgc aagtttttgg
     6121 tctttgttag atccggctat tacaaaagca gaagaaaatg gagatattgc ttggctagtt
     6181 gtaagtattg ggtttggttt aggcggtgtg tttttatata tggcagataa aacactgccc
     6241 catatgcatt ttggaccaca acatgaagca gaaggattgc ctacccattt aaaacggacg
     6301 atcttgcttg ttttttctat tacattgcat aacattcctg aaggtttagc cgtgggggta
     6361 gcattcggtg cagcagcaac tgcggataat ccgacagccg ctatattagc cgctgtttcg
     6421 gtggcgctag gtattggtat ccaaaacttc ccagaaggag cagctgtatc aatcccgttg
     6481 cgacaagaag gtctgagtcg taaaaaggcc tttgtttacg gacaagcttc tggaatcgtt
     6541 gaaccaattg ctggagtgat tggagcgcta ctagtaacga aagtggagct gctgcttcct
     6601 tatgcacttg cttttgccgc aggagcaatg atttatgtcg tggtggaaga attgatccct
     6661 gaagcacagc agacattgtc cagcaaacgt cattttgcag tttttggcgt catgagtgga
     6721 tttatcatta tgatgatttt ggatgtggca ttaggataaa taaaaaaaat atatatgata
     6781 tatcaaatag ggccgcgaac ttatatcgcg accctatttt tttagtaagt tatatcataa
     6841 tgaagtgaat ggtatcatac attaataata gttttttcta tgtgtatttc ctttgatcca
     6901 gcgaacaagc cagatgataa gtgcgattgg gattagaact ttgaccgcaa accataaaag
     6961 cccgcttagg acactgacaa aaagactgat gacgaagcta gctgcaatta gcactaaaag
     7021 aaccatgaag atatttaaga acatattttt ttgacgcata caaaaccctc ctcttgttca
     7081 ttctttacta tagaaaaagt ataacaggga ttgtttaaaa acacctccaa ctgaagactg
     7141 atttttactt catctactta aatgatcaaa caattgcttt ttctctggtt tatcatctaa
     7201 aatagagcgg aaaaggagga gaatatcatg cctaaaaatc gtcttgaagc atttacagat
     7261 gctgtaatcg cgattatcat gactatttta gttttagaac ttcatgaacc taacggagac
     7321 acgtgggagg cgctcgctgc attaggttac cgatttttta tctatattgt cagttttatc
     7381 attttagcga tttattggaa caatcatcat catttatttc aagttgtaca taagataaat
     7441 ggacgggtct tatgggcgaa cagtttcttt gtttttgcgc tttcgctttt tccgtttgca
     7501 acttcatgga tcagtgagta catcaatagc ctggctccag aaatgactta tggttttgtt
     7561 accttgaccg ctaatattgc gtattatatc ttggcaaaag aacttgtcaa agcaaataaa
     7621 ggccacgaga aagcattgaa ggcgatgttg aataattaca agaaatcgta tctatcgatt
     7681 ggtttgaatg tgttaggaat tgtcttaggg tatttagtag cgccagtagc cgtgctgatc
     7741 gcaaacatcg tgattctagc tgcttggatc atcccaagtc gtaccatcga atcacaatat
     7801 cggtaaaatg atccgtgttt aaaatttaag agaaaaatat agaaaaaata aataaacgat
     7861 caaatatccg agtgatacta gtattcaaag agggatgcag atggatcaaa aaagaattca
     7921 tgtaggactg attactagtt ttgtcacgat gcttatttat ttggatcaag gtcatttgac
     7981 ttggacagta gttggtgtcg taggattttt gacattattc acagcaataa aaaaataaac
     8041 atctttatgt aatctgatgt tctatctatt taagaaaagc atgtttacag cagtatgatt
     8101 ctgttgtaaa cgtgttttta tttgtggaaa atttaatttt tagaaaagtg tatcgaaaaa
     8161 tagatagtta gtttttccac agtggataac ttcgtaagag ataaaaataa aaaattagtc
     8221 aaagaagggc gtatagattt cttttgatag gagatataca acagaaatga ataaatatta
     8281 acgtgttttc aaacagtata aaacggtgtg gtttttggaa taaaaaaata acatatctca
     8341 ttttacgctt ttgttatttt atacttaaaa aataacgaca cagaaaatac cgtgtctcag
     8401 atttctctac tacttctaaa aactactgtt tttttccttt gaaatgcctt caaaaagtag
     8461 gatcaggcag aatatactgg cagaatcaag gagaagggag cctaaataag gagaaaaacc
     8521 atagaaaata taaagtaatt acttataaaa caagcttttt atagaaaaat aatatacctg
     8581 agtagggtat aaattaagac ggaattcctt tctagattga gatattgact aggaagaatg
     8641 ttaagatttt aagcctttaa gctaaaaaaa aacccttttt gttaaataag gggaatatag
     8701 cctgtcagtt tcaaactgca agtcgtcctg ctgcaataat atagtagatt agagatgaaa
     8761 atagattttt ttaaaccaat gactgaataa aaagaccgtc atagatacac attggaatgt
     8821 gtctattacg gtcttttttt acgaacgatt ttattgaaga cggacagttc gggtcaaaaa
     8881 taaaaaagct acgatcagaa ataagaataa aatgtatccc aaaataatgg ctagacggtc
     8941 taacttattt gtcgatagat gtttgtttag aagttgatag gcccataaac ctatcagtcc
     9001 tcctgttgta ttagttatca aatcagtgat gtccgctacg ccaataccga ataggaattg
     9061 aatcaattct gccaagaagc ttacaaggaa aataatccct aattttttag aaaaagaaag
     9121 tctcttgaaa ttgacattca aaagcacccc aaaaggaaaa aagacaatca agttataagt
     9181 ggtctcacgt aataccgtcg tattttcaaa agaaaaagta gaaaaaggga cgagattgac
     9241 attgctgtaa gaataagtga gaaattgtgg aagattaaat gatagcttga ataaaatcaa
     9301 ccataataga aagaataaat aaatccctaa taaaaatttt gatacatacc gcatagacat
     9361 ctcctccatt taaaaagtat accatcgaaa accgctgaaa aatcataaaa aagtatgaag
     9421 tttaaggacc aacgtagtta tcgtacgaaa attagaagct tttttttgtt gggaatccgg
     9481 tttctttaac aaagctaaga tagcgagttg cttggaaaag ttgctatctt ttttctgtca
     9541 aaacgactcg gaatgttcgt tttttgttct aatttctcca agttgtttac tttttgatac
     9601 taagtttatg aaaaatcaag aaatagttgt tatactaggt aatgctgaca aacgggattg
     9661 gcatttcatc ttggttcagc tttttttcca attactagga aggagggata gattgttcaa
     9721 gacttatttt cgtttcaata aaatacaaga taatcctttt cgtatcatga atctgatgct
     9781 acttatcttt attgtattat ggttaggtta cataaatcat gattttttga tttcaagttt
     9841 ttcatcatta gggatcttta cttttttcta ttatcaaaac ataccgatga aatatttgct
     9901 gaaacgtatg tttctgatcg gttgcggact gttggttgct ttcgttttgg ggatcttatc
     9961 gacttatgtt ttatggcttg aaccatttgc cgtagctttg gttgcttttt ccagcagatt
    10021 cgtgttgcga ttattccata tttctaaacc aggtggcttg ttttttgcga tgctttctgc
    10081 catgggaacg agcatgcagc tgccaatcgc tcaattaccg atcgtctcac tttatttttt
    10141 tatgggtgtc gtttttgccc tgattgcggc agtgattaca aaattactgg attcacggcc
    10201 tgagcagaca attgaaaaag caactttaaa agaaagattt cacgaagagc ctttagtgat
    10261 cattgattct gttttctaca gcgctgcctt atttctttcc gtttatgtca gtcacggctt
    10321 gaatctgcat aatccttatt ggttgacctt gtcatgtgca tcgattttgc tagcagaaaa
    10381 cttggatgcg atgaagcatc gacaagtcca atatctgatt ggatcgatgg gtgggttatg
    10441 tgtgtcggca ttcttgtcat ttgtgccgtt tacgcagttg cagaccattt ttctgatcac
    10501 ttttctatat ggaatcgcac aatttctagt tgctagaaat tatgcagttg ctaatatttt
    10561 tcttaatccg atggcgttga tgctatctac acttattcgt ggagcatact tgatttcttt
    10621 gatcgaatat cgttttttag ggatcgtcat aggaagtttc atcggtttag gtgttgcgtg
    10681 ggtaatgacg gttggtttgc aacattattt aacggttgtt cgtcaaaaat tagaatagaa
    10741 ggacaaatat atgtgccaaa agaggttatg acaagatttt tgtcacaacc tctaattcaa
    10801 ggtgttcaaa agccagattc tcagcattaa gtcaaattca cacaaaaatg tggaaaggaa
    10861 ctttcaaaaa aattttatat ttattctatc aaaaaatttt atatttattc tatcaaaaaa
    10921 ttttgtttat gatggtaact gaataaactt tcctgagatg gtcaatgctt tccttgaaag
    10981 tcttacagat attctttctt catagaaagt ttaagtttta tagttagtgt acaataaaag
    11041 tatgtttata ccatatggtg tccggataat cagtcattta aacaatgagg ttcaaagata
    11101 tgaaaagggg aaatttgatg aagaaaataa gcaatgaaat ccaaattctg gcagaaactt
    11161 taactcttcc caaagtcgtt atagagcaaa tgattgtaca agcaaaaaac atccttgatg
    11221 aggtgtttga gcaatatagt catgaactaa tggatcctaa taaagcaaag gcgactgcaa
    11281 agaaaataga caaagtctat gaagaggaac cttttgcagc attagctatt tatctatatg
    11341 cagcttctca aagttggaaa aaaatttatc aaccattgaa gattccaaga actatctatt
    11401 tggcaacaat gaatgctttt actagattta ttcatgaaca tttccaagta acaggaagct
    11461 atcgctttga ccgtggtttt tggatttggc attacactag tggcttgatc tttcggattg
    11521 gtgaattgga gtacgaaatg acatattttc cgaaagggta cacggatcta agattagaag
    11581 gaaagcagtg cctttctctt catattcctt ccgatgcaga tttatctcag aataagataa
    11641 gagatagtta cgaaagtgcc attcgttttt ttgaacttta ttttcctgat taccattacc
    11701 aagtgatgta cacagatact tggttactat cacccaatct tactaaatgg ttgaaaaaag
    11761 agtcaaaaat ctgtcttttt gcagccgatt atcgattatt atcagttgat gaacaggacg
    11821 atagtggagt cccttggatc tttggacgag tagatgccca aatacatgat tatccagaaa
    11881 gtacgagttt acagcgacaa gcaaaagagc aattgcttgc aggcgagcac attggctctg
    11941 gcttaggtat tcttacttca taagtttagt acttcgaaat agtttaaaag agcgtgagac
    12001 aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg aagcagaagc
    12061 aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt cgtgaatttc
    12121 ttcttatttc ttggagttaa acgcttctgt cccagcctct tttttagtgt tctatcgaac
    12181 acacagtacg ttcaataggt aaactagcta taacaataga tattaaagtt aacggacaag
    12241 agggcctttt ttaggtagct aaaacgtaat aatgaaaatt tatttccaga gataggagtc
    12301 aatcagctag tctgatcgac tgttttaaca agttgacttt cattttaact tttgatacca
    12361 tttaaaacac aaatcgtaat tgtttcgatt tgtgtttttt agcatgacta caatcaaaga
    12421 agaaagtggg tcgtccatat ggaaaaaaca gatatctcaa gtgcataccg ccgcttgaaa
    12481 agcccaaata tcaaaacacg aaaacgtgcg ctgaagatca tcaaagatgt gaaacggaat
    12541 agtgggaaaa ggtaagaaga aggaaactta attaaaaaaa tagccgaaaa acgtttttcg
    12601 gctattttca ataatcggtt tttgtgtaag gtttccgaaa gaactgctgt tgattttcca
    12661 tttttaacat atgataaatt ggtagaatct ttcttttcaa attgatacca ttccctaatt
    12721 ccagttatat agttaactac agaaccacaa agcacgtacg tttataaaag tattatctgt
    12781 agttattttt caattccctt tcaacctctt attttgacca gtagtattga tcactttacc
    12841 ttttaacacc tttgttcgtt tttgaaacat ttttagtcaa gaatggaaac gtaactacat
    12901 aatcaaaggt tttgcgaaat atttcatgaa atatttcatg tagaagcgag caatacggtt
    12961 gcaaataacc attatcgttt aataagcagt tacgaaagct cccaatatct ctaacgttca
    13021 gctcactcca tttcttttct tcaaaaaaat cagtgattcg tatctctttc tatttgtcga
    13081 aaaagttaac tttaaaaagt aacgccgaaa aaatatgcaa aaaaataaaa aagcagttac
    13141 tattgctaga ataacatcaa ggaataataa gttttggttt tcagataata gtcgataagt
    13201 tgtgtattgg aattttagat acagtaataa agtatttttc atgaaatttt gtgagaatca
    13261 ctattacaag tatctttaat aaaattaatg gttaaggagg aacttaaagt agaatgtaaa
    13321 tgaatagttg tagtcagtcg attgtgatac tagactcaaa gttgcaggaa taagtttttc
    13381 aatttgtgat tggaagataa aaaatgaaaa agaagggctt ttttttatac tttgttgatt
    13441 gtagtgttta ttttccctct gtttagccaa gtaacatttt ctatgactca accagtttca
    13501 agtgaggaac atgataacct ttttcgtgct acagaagagt ttaagaaata tcaggaaaat
    13561 attgttccgg agactccatt agctagtgag ccaattactg atattgatgg aaaccaaata
    13621 ggatggtata tacagtacga agttatggtg gtaaataatg actcaatagt aaaaaataca
    13681 gtaggcttag agctaacacc gattgaaaag gtgagttcat tgttaacgta tatttatact
    13741 gatgaaagtg acgagactga gatcatttta acggattact caaaaattgc tactgataaa
    13801 aagtatatat tgtggatgta gacactagtg aaatacttta tgatatagaa attgatgaaa
    13861 atttactaga tgtagcacaa gaaatcgatc atcaaaagca ggaagctatt cgatatgctg
    13921 gtagaaaagg gaaaagaaaa tatttattac gtgaatgtag caaaagttag agaagatgaa
    13981 aatgagtgga aagaattcaa gagtcgctac tcaattaact cgactccgac atttacagtt
    14041 tacagagaag gatcgataga aaaaactgtt ttttggacta aagaaagtgg aatgtcttta
    14101 gctgaagtag aagagttttt ggattatgtt agtatgcaac agtaagggag ttcttattat
    14161 gaaaaatttt gacacatatt atgttattgt tttttcgata tctttgctgt taatattact
    14221 aactttaatg cagtataaag agtatccaga gtattttatt ttaacttttg tatatttagt
    14281 aagtagctac acacttctat ataaattcag aagttcttct agagtttcta aagtttgttt
    14341 cttaattagc ttattgattc tataatattt ttgatttata taggaaatta aaaatattat
    14401 agaatcaaca ctcagagaac gggttggttt ttaatagatt taataagtac tgataatgaa
    14461 atttctcctg gttgggaaaa cgaagttggt taccctgtag aagaattttt tcaagattac
    14521 tttgcggagt atgccgatag gataatgaga gattacgtaa cagataaaac tcaagaagtc
    14581 atcaatcaat cccagtcatt aaatgaatta tctgataagg cgaaagaaga agcagttgcc
    14641 attatttctt cagggattag tgactatatt gatatgagtg gtgaaatcaa ttatggcgat
    14701 aaagacaaaa ttgtacgcat gataaaagct tttatcaaaa cttttgatgt gaaggcagat
    14761 cttaagttta atgatactta cctagtagga aaattaatta atatccttgg gacagagaaa
    14821 gatacggaaa cgtttatttc ctctttgtct atgttgttta cagataagca tttttcaact
    14881 cagcttggtg gagaggaact agtggaaatc ttttaaccat tacgcccagc attaataaaa
    14941 gtatatcaaa aaagtactcc tgatgatttt taagattggt ttgagaaata atgtgaaaac
    15001 actattttta atgttaatta tagatagaga tgaacgcgtc atatggttaa aagaatgaaa
    15061 aagtcaaaga tacactgcta tatttcacta aggatatagc agtgtatctt tcatgtcgtt
    15121 tcactggcag ttttttataa aaggaggtgt gcatttcagt tgcttttctt tggtagttag
    15181 ttgaatcgtt taagaattaa cggatgtggc agacaggtgc tctgtccaaa aaccagtaaa
    15241 atctttgatg gttccatctt tatttagctg tgcctgttca aatactgttt tgtttttacc
    15301 gaatggatca attgcaataa ttgttccgat ccccgcacgt ttggcagcaa gtaatcctga
    15361 gtaagcatct tcgataacaa gacaatcagc cggagctaag ctcagtttgt ctgccgcttt
    15421 aagaaaaata tccggttgcg gtttcccagg gaaagagccg tcgtcataga caatcttgtc
    15481 ccagtcaaac cagcgggcta aatcgaaaat atcaaaataa aaagcaacat tctctttgac
    15541 agtagccgtg gcaatcgtta atggaatctg ttggtcagtc agctggtcaa gagtcgcttc
    15601 aagccctttt gtcaactgaa gctcgttttc attttgcaag caaagcatac gataatagct
    15661 ttctttttct tctgacaata cggcgatctc agaggcggtc aaatgctctg aaatgaaatg
    15721 tttcaaaatc tccgtattcg tccgaccatg aatatttttt aaaatatcct cgtctgataa
    15781 accatctttt gtatgatcat gtatcatatg cagccaagca gcttcatgca gatgagagtc
    15841 caaaaacatt gttccgttga aatcaaatat aatccctttc atagttacgc tcctatagtg
    15901 gtattttcgg ttgaatcagc aatttgcaga tcgacatatt gtgcatagtg ctcttgaacc
    15961 tcccgcgaga tctggcgatc cgtaatgagc agatcgaaat catgcaaatt ataaaacaca
    16021 taaaaatcat ctcgattgaa ttttttatta tcaacgagta gatatttctt acgggaatta
    16081 tttagagcga tctgctgtgc ttctccttct tcggtactgt aagtagagat cgcttcgttg
    16141 tgaacgccat ttgaactgat aaatgctttt gtaaacttta gtcttcttaa attgtcgttg
    16201 gtgatcggtc cgacaaatgc gccggtattt ttccggaaat caccgccaat cagtagaatt
    16261 tctggtccat ctgcttgagc aagaatatca aaaactggat aattatttgt aatgatccga
    16321 attttcttgt tcagtaaatg cgtcgccaat agttcgattg ttgtacctgg tcctaagaaa
    16381 atcgtttctc cctcgtgaat caaggaggct gctgtggcag caatttcttt tttttcttga
    16441 atctgcagag tggctttttc agtgtgagaa agttcttgat ctaaagtgta ggaaagactt
    16501 tgagcccctc catggacacg cagcagcttg cccgattttt ctaattcatc taaatctctg
    16561 cgaacggtca tatcagaaac atctaattga ttgatgattt cattaacggt aaggattcct
    16621 tttttattga ccatttctac gatagtaagc aatctttctt ttttcaacat tgtcttcacc
    16681 tctaatttaa ggataatcta tcatataaac ggacaacagt caatctaatt cgaacaaaag
    16741 taaacattta gggtggtttt tatgtttgtt acaatagatt ttattgctgt tttctggttt
    16801 ttatgattat ttgtgtttgt ttttgttgac aaatgttttg gatgcgttta caatgcaatc
    16861 agttagaaag agcgaaaact gattatagat ttgaggagag atgtacatgc ttaaattacc
    16921 agaagatttt atttttggcg gagccacagc agcctatcag gttgaaggag ccactaagga
    16981 aggtggcaaa ggcgctgttg cttgggatga ctttttagag gaacaagggc gattcagtcc
    17041 cgatccggca agtgattttt atcatcaata tgcaaaggac attgaattgt gtgaacgttt
    17101 tggtgtaaat ggtctaagat tatccattgc ttggagccgc atttttcctg atggagctgg
    17161 gaaaccaaat ccagaaggaa tcgcttttta tcatcgtgtg ttcgaagaat gtaagaaaag
    17221 aaacgtaacg ccgtttgtga cgttgcatca ttttgatacc cctaaacgtt tgtttgacca
    17281 tggagatttt ttgaatcgag aaacaataga agcatttgtt tcctatgcca ttttttgttt
    17341 tcatgaattc aaagaagtca aggtgtggag tacctttaat gaaatctatc cagttgcaac
    17401 caatcaatat ttgttaggtg ttttcccacc aggaatcaaa tatgatttta caaagatcgt
    17461 cgcctgtctt cataatatga tggttgctca tgcccgtgta gtgaactatt tcaaagaaaa
    17521 cgaacttccg ggtgaaattg gtgtagttca ctcattagag acgaaatatg cggcaacaga
    17581 cgcgccggaa gataagcatg ctgccttttt agacgatgca ttgtcgatcc gtttcttatt
    17641 agatgctacc tatttaggct attattcaac tgaaaccttg actgctcttg atgagatatg
    17701 tgaagcaaat caggccagct atcattttcc tgaagaagat ttcgttgaat tgaaaaaagc
    17761 atccacgcgt aatgactact tagggatcaa tcactaccaa tgccattttg tcaaagctta
    17821 cgatggagaa aatgcaatcc atcataacgg tacgggtgaa aaagggacct ctgtttataa
    17881 agtgaaggga atcggagaac gtatttataa agaaggaatt cctcgaactg attgggactg
    17941 gctgatttat ccagaaggtc tatatgactt gttgctgcga attaaaagcg attacccaca
    18001 ttacaacaaa atctatatca ctgagaacgg gatggggtat aaagatcagt ttgaagatgg
    18061 cattattatg gatcagccga gaatcgacta tttgagagtc tatttggaat ccttaagcaa
    18121 ggcgataaca gccggggtaa atgtgaaggg gtattttttg tggtcgctta tggatctttt
    18181 ctcatggaca aatgggtata acaaaaggta tggcttgttt tatgttgatt ttgaaaccca
    18241 gaagcgttac ccaaaagaat cagcttactg gtacaagttg gtcagtgaaa ccaaaacgat
    18301 tatttaataa gtgataatgg aggaagaaaa gatgaataaa gaggaattac aaatgcttgg
    18361 ttttgagatc gttgcatatt caggcgacgc tcgcagtaca ttattgaaat tattgaaaga
    18421 agtaagacaa ggaaactttg aacatgttga ttcggcgttg aaagaagccg acgaaaattt
    18481 aacccttgca cataattcgc aaacaaaaat tttagcggaa gaagcatctg ggaaagagat
    18541 ggagatggga ttcattttta tccatgggca ggatcattta atgaccactt tattgctgag
    18601 agatctgatt caagacttta ttgtactgta cagacagaat caaggatagg agaagaacgc
    18661 tatggatgga atcattaaac aaatcgaaaa agggaaacca ttttttgaaa aaatctcacg
    18721 taatagttat ttaggagccg ttcgtgacgg atttttaaca gcgatgccag ctattttatt
    18781 ttcaagcatt ttcattttga ttgctgcggt tcctgagatt tttggttacc aatggcctga
    18841 atctgtctcc acatggctat ggaaagtcta taattattcg atgggtgttg tagggttact
    18901 cgtttcagca accactgctc gctgcttggc tgattcgatg aatcgtcgct taccgaaaaa
    18961 caaagtaatc aacaccacct ctgtgatgct ggcctctgtg gtaagtttcc tgttgttaag
    19021 cgtctctccg attgaaggtg gattttcaac ggaatatatg gggacaaagg gactactggc
    19081 ttcctttgtc gctgcatttt taacagttaa tttatataag ttttgtgtgc tgaaagatat
    19141 taccattaaa atgcctaaag aagttcctgg aacgatttcg caaaccttcc gagatatttt
    19201 tcctttctct ttttcagtat ttgcggccgt tttaattgat ttaggcattc gacaaatctt
    19261 ccaaatctca tttgcagaag caatcattac ggtgctgcag ccgctattta cagcagctga
    19321 cgggtactta ggaatcgcta ttatctgggg agcgatggcg ctgttttggt ttgtcggtgt
    19381 tcatggaccg tcgatcgtgg agccggcaat tgcggcaatt atctatgcca atgtggaaac
    19441 caatctgcaa ttgttcaatt ccggtgaaca agcttctaaa gtactgacgg tgggtttagg
    19501 gaattttgta ggaactatgg gaggaactgg ggcaacattg gttgttcctt ttatcttcct
    19561 actctttgct aagtctaagc agttgaaggc agttgggaaa gcttccttta ttccagtaag
    19621 tttcgctgtc aacgaaccat tgctatttgc ggcacccatg attttgaacc cttatttttt
    19681 tattccattt ttgttaacac ctgttgtaaa cgtttgcctg ttcaagtttt ttgtcgatgt
    19741 attgggcatg aacagcttta tgtacgtttt gccttgggca actccagcac cgatcggttt
    19801 ggttctagga acgggcatgg gtatcttagc ttttgttcta gcagcggttc taatcgtcgt
    19861 tgacttcctg atctatctac cattttgcaa agcatacgat gctgtcttag tagagaaaga
    19921 agcacaaaaa gcagaggtga tcgcaaccga ggaaggtgct tctgccgatg tacgtgagga
    19981 agtacctgtg gcagcgagtc aagttatcag cgatgcaaat aaagaaatca atgtgttggt
    20041 actttgtgct ggcgcaggga caagtgcgat gttagctaat gctttaaaaa aaggtgcatc
    20101 tgaatcgaaa gcaccgatca gtgcaatggc gggtgcttat ggttctcatt acgaaatgct
    20161 gcaggatttt gatatggtgg tcttagcacc gcaagtcaat tcttactatg atgatatcaa
    20221 agaagacacc gatcgcttag gaatcaagct ggttgcgaca aaaggagcag aatatatcgg
    20281 attaacgaga gatcctgaaa aagctgttca gtttattctg aaccaatttc aataaaggag
    20341 gagccataat gaaaatggga atttggttgc gtaaagctgt tttatttgca gctgtgttag
    20401 gggctttggg ggctgtttca aaaactgttg aagcatctgc cagcgaattt attcgcggag
    20461 cagatatttc gatcctgtca gatatggaaa aatctggtgc aaaatattat gaagacgata
    20521 tttcaaaaga tgccttagag attttaaaaa ataatggtgt caactatgtt cgactgcgtt
    20581 tgtggcagga tccttataat agtaatggag aaagttatgg agcagggaca aatgatctgg
    20641 aaacgacgat tgaccttgca aaacgagcaa aaaatctggg acttaaggtg ctgctggatt
    20701 ttcactacag tgatttttgg gttgatcctg ggaaacagaa tcttcctaaa gcatggcaag
    20761 gtctgacctt tgaagaaatg aatacggcat tgtacgacta tacaaagaac gttctgtcgg
    20821 aaatgaagca gctggacgtt tatcctgata tggttcagat cggcaatgaa ctgaatagcg
    20881 gaatgctctg gccttatggc aagtcttggg gagaaggcgg gggagaattt gatcgattgg
    20941 ctgctttttt gaagtctggt atccaagctg ttcgagacac tcaacctaaa acaactccag
    21001 taatgctcca cttagctgat ggtggcgata caggagcatt tacttggtgg tttgatgaaa
    21061 tcacgagtcg aggtgtgtca tttgatttaa ttggagtgtc gtattatccg tattggcacg
    21121 gttcaatgaa tgaacttcaa accaatatga atgcgatcag ccaacggtat ggtaaagaag
    21181 tgatcgtagt tgaaacagct tatgggcata caacagcgaa tgccgatact atgccaaatg
    21241 cttttggtga agccgaagca gctgcggggg gatatgaacc aacaccgaca ggacaagcag
    21301 agtatttgct ggatcttgcc gatcggattc aggcagtacc gaataatcgc ggggcgggct
    21361 tcttctattg ggaacctctt tggtacaacg gaaatgtgag ttgggcaaca caagcaggta
    21421 tgaattatct cagtgttcaa tccactatgg gaaacgaatg ggacaaccaa gcgatgtttg
    21481 attttgctgg aaacgccttg ccaagcttgc gtgcgtttaa acaagcaggg gcgcaaataa
    21541 atctagttaa aaatgcaagt ttcgaaagcg atggaccaac gaccagtcct tccaattggc
    21601 aaacctggtt tcaacaagga accgctaagg gtacgatcaa aacggaagcg ggcacttttt
    21661 ttggggacta caaactaact ttttggcagg atcaagcata cgaggcatca gcttatcaaa
    21721 atgttagtgg cataagcaaa ggaacttaca cattgagtgc ctatgtaatg tctgggggag
    21781 agtttgatac taatcagtta tatatcaaaa attatggtgg agcggaacta aatactgcgg
    21841 ttgttaaaac aagtgaatgg acaaaaatta caatcaaaga cattccaatt acaacaggtg
    21901 tttgtgaaat tggggtttat agcaaggctt caggaaatgc ttggacgaac gttgattttg
    21961 tttcattggt gaaacaatag actgcggatc gtttcgattc aagatcggag gttcccttca
    22021 gccacatcgt tagcgtagaa ggcaggaatc gaacctgcac ctcgcctttg ccaaaaataa
    22081 ccagaaacga tttccagtca tttttaccaa aacgagtaaa gcaccagact tcatctacac
    22141 tttgtattat gctaaagaga gttcaacgat ttcgtaagaa gcaatgaaaa aattgcaaaa
    22201 agttgtgcag ataacataaa gtttgtttaa gaaagggtaa ccttagaatt ccgtcgtgaa
    22261 tatgatttga gcacttagat ggatagaaaa aagttctcgg aaaacagttc gtttttcgag
    22321 aacttctttt tatgataaga atgaaacaaa ttaacttata ttatagtctc ttttggtagg
    22381 gaaccatctt atttttaatg aaaatcaagc attttagcta ttgaagaatg ttgatttata
    22441 gggattcccc ctccatatta tgttggctct ttattcccac tctgttttca acgtaaagtg
    22501 tataaaacag aatgcgatac tatcaaggga gttaaaacaa tatacagaac agtaaaacac
    22561 tataaataaa aataaaagtg caataaaagt gcaatttttg cacctaatca tactctgttt
    22621 atatatgaaa actagattct gaatccaata tttggttaac gagaggcgtt cgaatttgaa
    22681 cgtcttttat atattacttt caaataaata tgaggtagaa tactatctat tttcttttta
    22741 acccaattgt tataatggag agtgtaaaat attttgtgta aatagaaaaa aggaagtccc
    22801 ttctgtagaa tagagttacc acaacacatt cacagaagag aggacttccc tatgaacgat
    22861 tttactacag aaattctaaa gactctagcg aacaaaggcg atttgaatga attattccgt
    22921 gtccatttgg agaaagcagt caatacgctt ctcaaaacgg agttaacggc tttcctagat
    22981 tacgaaaagt atgatcgcat tggttttaac acgggtaatt ctcgtaacgg ctcctatgac
    23041 cgtacggtca agaccgagta tggggaactt catctccaga ttccgcgcga ccgcaatggt
    23101 gagttcaagc aacagactgt tcctgcttat agacggacga atgacacgtt agaggagacc
    23161 gtcattcacc tcttccgaaa aggtattacc atgtcggaaa tcgcagactt gattgagaaa
    23221 atgtatgggc attactacac gccccaaacc atgtccaata taacaaaatc atttacagaa
    23281 gaggtaacgg cgtttaatgg gcgggagctt catgaccgtt atgctgctat ttatatggac
    23341 gcaacgtata ttccgttaaa gcggaaaacc gtcgccaagg aagctattca tatcgcagtt
    23401 ggcattcgcc cggacggatc aaaggaagta ttgagctatg cgattgcacc gactgaatcc
    23461 atcacgattt gggaggaaat tttattggac cttcaagagc gcggtttgaa aaatgtcctc
    23521 ctgttcatca cggatggctt aaaggggatg gtaggagcga ttagtcggtt ctatcccaaa
    23581 gctcgttttc aacattgttg tgtacacgtt tcccgtaata tcagtcataa agtgcgtgtc
    23641 gatgatcgta aggaagtctg tgatgatttt aaaatggtgt atcaagcctc atctaaagag
    23701 gtggcgttgg aagcacgtgg tacttttgcg gaaaaatgga aaaccagcta tccaaaagtg
    23761 gttgaatcga ttctttcgaa cgatcacttg ctcactttct atgatttccc cttggccata
    23821 cgcaagagta tttattctac gaacttgatt gaatccttta ataaacaaat caagaaatac
    23881 agccaccgca aggaacagtt ccaaaatgaa gagtcgatgg aacgtttctt agtctcgtct
    23941 tttgatactt acaaccaaaa attcctaggt cgcagtcata aaggtttcca acaggccgaa
    24001 ggcgagctcg aacaaatgct aagccaactg attgagaatt agaaacaatc tgcagtaggg
    24061 aagaatcatt tacacaaaat tattgacgct cccttataat gagaactttt actaacataa
    24121 tttatgataa acttactata taatcatatt aattaaatag ttaggagatc tgcttatgtt
    24181 tatatctact cttcaaattc gaaattttag aaattatgaa tccgaaatct ttcgattcga
    24241 taatgagaca aatactatta taggtgagaa tgattcaggg aaaaccaatg ctcttactgc
    24301 attgagaatc ttattagatg atagttatta ctatagtagt aaaacactaa aagaatcaga
    24361 tttttttcat ggaattcaaa atgggtggca agggcattgg attattatct ctgcgacatt
    24421 tgaaggaatc agcgaagaag aatttgacaa tgagatttgt gcttccattt ctttaaattc
    24481 tgaaagtcaa acaatcttag aagaattgat ttcaaatgca gataaaggtg taggtagtat
    24541 ttctctattt attagaccta acaaagctat tagaaagcaa ttatttgata tttccactga
    24601 attagactct catcaattta acgaatttag aaattctatt cgtctatccg actatgaatt
    24661 ttactacaca tctaaatcaa atctaaattt ctgtatcaat gaaaattatg ataaattggt
    24721 aggaagactc aatgacaata tagctagtaa tcctgaagaa gacgatgaag ctctgttggg
    24781 ctcaagaatt gacatgtcag atattttcaa gcatatttcg gttgtttatg ttgacgctct
    24841 tcgagatgtt cttagagaaa tgaaaaacaa tcgaaaccca gtcaaaagaa tcatggaaac
    24901 aattgaatca aaaatatcat cagataatgt tgagtcatta aaaacaatta tacagcaatt
    24961 aaatgagact attaccagtg ttcctgaaat taggaaaatt ggcgaaaata ttaatcggca
    25021 actaaatagc ataattggtt cagtgtattc tcctaatctt cttctttcct caactatgtc
    25081 agatgatatg ggttctttag caaaatttct ttcaatgaag ccagaacaaa atatcgactt
    25141 agacttacta gggttaggac atctaaatat gatttattta gctttgaaaa tagtcgaatt
    25201 tgaagcgtgt cgttcaagag aactacttaa tattatgttg attgaagaac cagaagctca
    25261 tattcatcat catattcaaa aaactctgtt cgaaggatta aatcttcaaa aaaactatac
    25321 tcagattctc atgaccacac attctgtaca tttagctgaa gtgtctgaaa tatctcggat
    25381 gaatgtatta aaatcgttta atggcaaatc tatcgttatg aatccagcaa ataatctgaa
    25441 ctcatttgct aaagaaaagt taaaaaagaa caatctaaat ctaataaacg cagtagagag
    25501 atatttagat gttaaaagaa atggattgct tttttctaaa ggtgttatct tagttgaagg
    25561 agatgctgaa gaaatactta ttcctcaaat agtaaaaaaa ttatttggta taaacttaga
    25621 cgaacttgga ataggtttga ttaatgttgg tagtacttcg tttgaatata tcgctagctt
    25681 gtttgacgat gatagaatac agagaaagtg tgctattgta actgatttag atgaacaggc
    25741 aatcccatca gaacatcgat tgtataaaag cactgcacaa gagaaaggtc aagcaagaaa
    25801 agaaaaatta tcctcccttt ttaatgaaaa caattgggtt aattgttttt atgctaatac
    25861 aacatttgaa attgagtttt tagatgtgaa taaagaaaat attctaactt atgtcagtcc
    25921 aattatagat gacgcattca aagataaaaa aacaataact gcttataaag aagaaataca
    25981 aagtgaacaa tatttagaaa gaaatttagc gatgttaaaa ctagccaatc atgttggtaa
    26041 ggggtggttt gcaattgagt taggtgaaaa aattgacttt ttaatcaaaa ttcctaagta
    26101 tattcttaat gctattgctt ttgcatgtca ggaaatagta gatctctcaa tttataaaaa
    26161 aattctactc catacaatcg acttgtacga ggaaactaca gaattgtcag ctttatcagc
    26221 tagtttaaaa acaagtgata cagctgattt gaatatagca ataatttctt tattagagta
    26281 ctttggtaaa gatgaggatg ttgtgtatct aatcaatcag atagaaaatt acacaaaaat
    26341 actttatgct gaggtttcaa aatgacaaat atcttcgaaa aaatcgtaaa tgatttaaat
    26401 ttagaacaaa aagatgttgt ggaaagtgaa gataaccttt atgtaaatgc atgtcctggg
    26461 agtgggaaaa caagggtact tacaaggaaa attgcttacc aagcaattaa acacgatgga
    26521 tcactaaaaa gaataattgc tatcacatac actaatagag ctgctgaaga aattaaggaa
    26581 cgcctaagtt tacttagtat agatgatgat attaatattt gggtggggac aatacatcag
    26641 ttttgtcttg aatttattat ttatcctttt aaaatgaatc tctcaagagt atcaaaagga
    26701 tttacaatta ttgatgatta tactcaaaga gcttacgtca gccaaattaa taatatgctg
    26761 aatttaaatc tcaaaacgta tgaactgaac aaaattgatt tgtcactttc tcatgatttt
    26821 aaaattaatg aagttcagta tactcaagtt tctgaaatgt atcacactat gttggaaaaa
    26881 aataaagaaa ttgattttga tatgatttta ctagtagcgt ataaaatttt aactgtaaac
    26941 agtaacgttg cacgtaatat tgctagtaat ataagggcga tttatgtgga tgaatttcaa
    27001 gatactagag aattacaata caatgtaata gctaaattac ttcaaaacaa ccctcaaatt
    27061 cagtcaatgt ttgttggaga tattgaccaa gcaatttatg gatcattaga tggtatagct
    27121 aaatcagttg aagaactaga aatgctaact agtcacactt ttcaatcaaa gacgctacat
    27181 ggctgttaca ggtctaatca gagattagta gacttctact ctaattttca gagttgtcct
    27241 tacgagattg aaagcagagg gaataataaa aacgaccgtg gttttataag ttatgattgc
    27301 aaagttacta aggaggattt acccaacata ataaaaaata taataaagga aaagattgaa
    27361 agcggcattc atgaaaaaga tatttgtgta cttgctcctc aacactatcc tctgttttca
    27421 ctgggtgagt atttaaagaa agaattaccg tattgcaatt ttgatgctat aaatatatca
    27481 ccaattaagg taaataatca tagtttattt ttcaagttag caattttgta ctttactgaa
    27541 tcaggtgaaa aggttcgaag aagaaagcta attgcaaacg atattttaat tatattaaaa
    27601 aatgaatttg gaatagaagt taaagattat tttattgact tagatttatt acagctaata
    27661 aacagtgtga aaagaatgta tagtggagac gacaacggtg ttgatttata caaatttgtt
    27721 accaaacata tatttgttaa tcttaatatt gacgagaaaa attacccgtc tatttttaag
    27781 cactatctat tttttattaa cgaagtagaa gatcggataa aaaataattc attatctagt
    27841 agtgtatcta gttttaagaa gatgtttaaa tctcgagatg gtatcacact tactacagca
    27901 cataaagtta aaggaaatga gtatgatact gttatcgcta ttaatcttct aaacgggaaa
    27961 attcctcatt ggaatgaaat ttttaatgtt tctgataaag gaattagttc agcgagaaaa
    28021 ctactatacg taatttgttc aagagcaaaa aataatttat ttcttttctc agaggtgggt
    28081 tattttacga gtaaaggaga cttgctttat cccactcaat tattagataa aatagaattt
    28141 gattataata tttaaaatac ctaggtagtc gttgttttaa atatagtagg aatcggacgc
    28201 tcagtacgga gcgtctattt ttttacccaa ttttgaaagg aagtgaactt atgaaaataa
    28261 aaaatcaaga atcaaaaggt cgctctcccc cctttaaaac catcacacaa ataagattca
    28321 ttcaaacata aaaacagaaa ggataggtaa aaatatggaa cttaaatatg tcattcccaa
    28381 tatggaaaaa acatttggac aattagaata tgctggtgaa gggaacattg aacaacgtcg
    28441 aataaatggc agaccaacca ttctctctcg tagttacaat ttatactcaa cgattcaacg
    28501 agcagatgat attgttgtca ttcttccctc cgaagctggc gagaaacatt ttgaatccga
    28561 cgaaaaagtc aaactcatca acccacatat taccgcagaa ggttataaaa ttggcaatcg
    28621 aggatttacc aattacatta tgcacgcaga cgatatggtg aaagcataag aaaggaaagg
    28681 tgaaaaaata tgagattagc agaaggtatt gtgattgaaa aagaccagac atttggcaca
    28741 ttgaaatttt ccgccttgcg tcgtgaggtt cgtatccaga atgaagatgg tacggtttcc
    28801 gaagaaatta aagaacgtac ctatgactta aaatcaaaag gacaaggacg catgatacaa
    28861 gtcagtatcc ccgcttctgt tcctttgaaa gaatttgact acaacgcaga agtggaatta
    28921 atcaatcctg tggcagatac cgtagcgacg gctacttttc gaggggcaga cgttgattgg
    28981 tacgtgaaag cagacgatct tgtattaaaa ggacagacaa aacctcatca gaaatataaa
    29041 aaagaagcgt ccgaaagtga aaaataggtg ttgcttatga caaacacacc attgattttg
    29101 aaagaaattc cgaaggatga agccatttct tttattcggc aataccatta ttcaaagata
    29161 ctccctagat tgtgtaaata ctttctaggg attttttcag aagaaaaatt attaggcgtt
    29221 gtggaattag gctggggtac gcaaccccta caaaccatac gcaaactctt tcccgacagt
    29281 tcccttcaaa ccacagatta tttagaaatt ggaaagatgt gttttcttcc agaaatgaat
    29341 caaaccaatt attttggcag tcaagctctt tcagctctaa ttaagtggtt gaaagaacat
    29401 acggactgtc attttttata tacactggca gatggaattg agggaaaatg tggctatgtc
    29461 tatcaagcgt ccaacttctt ttactgcggg tatttcaaga caagtgtcta tcgtgataag
    29521 cagtcatggg aaaagataca ccctcgaagt gctcgccttt tattagagga aaatgctcgc
    29581 tttgaacagg tagagaaaaa gcattggctt tcccaggcat tttgcgaata caaagggatt
    29641 gagaaaatca atggacgcat gtttcgctat ctctatccgt tgacaaaaga agcgaaaaaa
    29701 ctgttaggac acactctcta tcgacgtcat tattatccga aagaaaaaaa tttacgcttt
    29761 gaaaagcgaa tcgcttatca gaaatatgaa gccatttctc aaccaacttt tgataaacag
    29821 gctcgtatct acaatacaca attattttga taggtggaaa ggaggatttt tatgccattg
    29881 cttcatgaca gaggagagcg aatcaaagcc aacgataagc acttggtcta tcattttgta
    29941 ctaatttcat tgctggtagt ttttctagtc gtcctactcc cttttcattg gagagcgtta
    30001 caatcggtga actggcaagc agttcagtta gatacatttt tctatcaact tcatacgcca
    30061 tacttttgga gcagtattct cactgctctt tttgtatgcg gacttatcag ctggctttat
    30121 tatcactatc gtatagattc tataaaacag ttagagcacc gtcaaaagtt agctcgtatg
    30181 attttagaaa atcattggta tgaagccgaa gaaactcaat cagagggatt ctttaaagat
    30241 ttacccagca agaaaaccaa acaacgaatc cgccattttc ctaaaatata ttatcgaatg
    30301 aaagatggac taatccatat tcatgtagaa atcaccttag ggaaatatca agatcagctt
    30361 ttgcacctag aaaacaaact agaaacagga ttgtattgtg aattagtgga aaaaacgttg
    30421 aaagattctt atgtagagta tgtcctactt tatgatacta ttggcaatcg aattggcatt
    30481 gaagacgtgg tagctcaaga tggacgtgtc aaattgatgg aatcggtcta ttgggagttc
    30541 gattctctcc ctcacatgtt aattgctggg ggcactggta gtggaaaatc ctattttatt
    30601 ctcacattga ttgaatctct cctgcataca aatgcaaagc tttatattct tgaccctaaa
    30661 aatgctgatt tggcagactt aggggcggtc atgaataatg tctattaccg taaagaagat
    30721 atgttggcat gtatcaatca attttacgaa gatatgattg atcgcagtga aaccatgaaa
    30781 caacacccta actataaaac aggagaaaat tatgcttatc ttggtttgtc tgccaatttt
    30841 cttatttttg atgaatatgt ggcaatgatg gatatgctag gtcgtgaaag taccaccgtt
    30901 attcataaac tcaaacaaat tgtaatgtta ggacgacaag caggcttctt tttaattctt
    30961 gcctgtcaac gtccagacgc aaaatatttt agtgatggga ttcgggacaa ctttaacttc
    31021 cgtgtggctt tgggtcgtat gtctgaaatg ggctttggta tgatgttcgg aagcgataca
    31081 caaaaacaat ttttcttaaa acccatcaag ggaagaggtt acgtggatac aggaaaaagt
    31141 gtgattagtg agttttatac accccttgta ccaaaaaggt acgatttctt aggagaaata
    31201 ggaaaagtca ttcaaaaaaa gcaatctgag cctgtaccgc acgaagtgaa aggtacaggt
    31261 tcagacttgc tttgattggt gtggcgttag ccacgccaat cctttagccc cctctatcta
    31321 acaggggggc acaaatacaa ctgaaaacag gcaattctca tcaaccaatg ttgatggtac
    31381 aaaggattgc ggaaaatatg aaaggtgtaa actcaagggt catagtttac atctttttta
    31441 gattggaggt ttgcgaatgg aaaacgaaaa aatttggatt aaggaattga aagaaaagcg
    31501 actggcttat ggcgtttctc aaaataaact ggcggttgct tctcatatta ccagacctta
    31561 cctatcggat attgaaacag gcaaggcagt ccctactcaa caggtgaaag aagatttact
    31621 gaacgctttg gaacgcttca atcccgataa cccattggag atgttattcg actatgtacg
    31681 gattcgattc cctaccaatg atgtggctca aattatcggt gaggttttac gtttgaatat
    31741 ggattatatg ctacacgaag actttggcta ttattcttat cccgaacact atcgtttcgg
    31801 tgatattgtt gtcctagtct ctcatgatgt aagtaaaggt gttttattag aactgaaagg
    31861 aaaaggctgt cggcaatttg aaaactttct attggctcaa catcggagct ggtatgattt
    31921 ctttcaagat tgcatggaac ataaaggtat tttcaaacgc ttggatttag ctatcaacga
    31981 taaaacaggg attttgaata ttccagattt ggcaaagaaa tgtaaacagg aagaatgcat
    32041 ttccgtcttt cgaagcttta aaaattatcg cagtggtgaa ttggttcacc gtgatgaaaa
    32101 accatacatg ggaaacacac tttatattgg ctcattaaaa agtgaagtct atttctgtat
    32161 atatgagaaa gattatgagc aatacgtgaa aaatgatgtt cccttagaag acgcagaagt
    32221 aaagaatcgg tttgaaattc ggttaaaaaa tgaccgagcc acccaagcca tgaaagattt
    32281 attggcacat caacaggcgg aaaaaacagc ctttgaaatt atcaatcgct atatccgctt
    32341 tgcagataaa gacgacacta aacgtcggag tgattggaaa actaatgaac gttgggaatg
    32401 gtttatcggt aaaaatcgtg gagcattacg cctaaccaca cagccagagc cttattcttt
    32461 tgaacgaaca ttgaactggt tacatcatca agtcgcccct acattaaaaa tcgcaagcat
    32521 tttagatgtt ctcaacggta caaccattat ctccaccatg attcaggaag ccaaactgac
    32581 agaaaaacat gagaaattaa ttgaacaaca acatctagcc atggaggatt tgattacatg
    32641 agccttttaa caaaagaatt aaagaagtta gggtttcagt gtggcattga gtttcaagcg
    32701 tatatacaaa atacagggaa atatacgtct ctcattattg agggaaaacg gcaagctggt
    32761 gataccatct atacctatga tttttacaag gtgagatttt ataataatta taccaatcga
    32821 gtaaccgtct atggagagca tttaacccct tttcaattat taaggcgtgt aaaaagctat
    32881 atctattatc gagaaaaata tcttaaggaa aggaggacaa tcacatgaat tttgggcaga
    32941 atttgtacaa ctggttcttg gataatgcac agtcattggt attgttagcg attgttgtca
    33001 ttggactgtt tttaggtttt aaacgagaat tttcaaaact cattggcttc ttgattattg
    33061 ctctaatcgc cgtcggactt gtgttcaatg cagctggcgt gaaagatgtg ttattaaact
    33121 tatttaaccg aatcattggt gcttaacaga tatttttcat gataaaatag gaagtatata
    33181 ttttgttatg aaaggattta tgaatatgtt tacaaatgat caatttaaat ctcttttaat
    33241 taaaacatta gaaagaaaga gctcttcaaa ttattatgaa ggaggtaacg agattgtttc
    33301 taaaatgaaa atatcagagg taactttaga tgagactgac gattttactt attataaagg
    33361 atataaaaag ggctggaata cgctttgcac atatcttaaa ataagagttc cttttgatga
    33421 tttagacttt tttgaaagtc ataaagattt gattacccag acagcaagct ccatatatga
    33481 taaacaaggt gataatgtat tagtggatac tattttagta ccacttccag agaattacga
    33541 agtaattaac tttagtcagt tgaaaattag tgatgtggtt tcacaagcta ttgaagacgc
    33601 tgagtctttt atgagtaatg gtgaatatca acgtgccttt gacagagttc acactgcttt
    33661 tcatggatat ttaattgaaa tactaaaaaa atatgaaatt acagttccta gagacgaaaa
    33721 tctatctaaa ttatatagta ggatacaaca attaattgaa aaagaaattc aacctactga
    33781 acttgctgat atagtgaaga caacgataag gtcatcaaat ggaatgatta gctctcttaa
    33841 tgaagcaaga aataggcatt cacttgcaca ccctaataca aatattattg gaaagagaga
    33901 agcaaaacta ataataggta tttcaagtac agttacagat tatattagcg gataccttga
    33961 taagtagcgt cattaactga ttgctacttt ttttatgact atttttataa aaaggatgtg
    34021 ataagaattg gaaatgaaag tctatgtggc aaatttagga cggtataatg aaggtgaatt
    34081 agtcggagca tggtttactc caccaattga tgaggaagaa atggcagaaa gaatcggttt
    34141 aaatgaggac tacgaagaat atgcaataca tgattttgag cttccttttg atgtggacga
    34201 atacacgccg attagtgaaa tcaaccgtct atgtgaagcc attcaagaaa tcgaaggtac
    34261 acctatttat aatgaactca aagaaattca aggcatgtgg tttagtagct tggaagaatt
    34321 actggaaaac aaagaggata ttcattgtta tagtgattgt gattcgatgg aagatgtcgc
    34381 ccgttattac gtggaagaaa caggacagct tggtgaagtc ccttccaatt tacaaaatta
    34441 tattgactac caatctttgg gacgtgatat ggaaatagag ggtaattacc tagttacctc
    34501 tcatggggta tttgaatatt gtcagtaagt ttaacaatcc gtgttataat taaattaata
    34561 aatagcacgg agaggtataa attatggtaa atgtatttga aaatcttaaa ctattaaaac
    34621 tagacatgaa agataaaggc tgggtgatag attcctttta ctttcgttac aaacagcaaa
    34681 attatattgt acttgttaag ctatttgaaa aagaggaaaa agttccagaa tatgctctgt
    34741 taaaactaga atttttaaag gaaaacgatt tttcagatat gctagctgtc tatgctaatt
    34801 cggtaaaatt atatacagac acgaaaacaa taagagaata ttttggtatc gaatacagta
    34861 gtaacttggg agatgtttta tttcaattta gccaaactct tgctcgattt attccgacag
    34921 aagttagtga gaagaaaaat gaagaccaaa aagaagccat gtgtttctca ttaagtcaaa
    34981 gtgattcaga agatcccaga aaaaaatatt gtttttcagt tagaagaaat cctttaaagg
    35041 gaaatggtga gctgggaaaa cgaagtcctt ttaatgacaa taaaacgaga ttgtatagac
    35101 ccagcttata tgaacgatta gggtcagata ccaatttaag tttcagatat tcaatgaatc
    35161 cagatgatga agaaactgat gaaggtatta ttgcaaaatg gacaaaaaat aaaattgaat
    35221 agttaaagca ttgaaagagc aatcacctat tttgattgtt ctttttctat ttttacggaa
    35281 aggacgtgaa gacatgaaaa aaataagaag ttacaccagt atttggtcag tagaaaaagt
    35341 gatttatgcg attaatgatt tacaactccc tttcccaatt acctttacgc aaatgacatg
    35401 gtttatcgtt tctttgtttg tcgtcatact ctttggcagt ttaccaccac tttctctgat
    35461 tgacggagca ctactcaaat acttagggat tcccattgtt ctcactgggt tcatgtgcca
    35521 aaagaccttt gacggaaaga aaccctatgg atttctaaag tctatcatta cctatgctct
    35581 acgccctaaa gtaacctacg ctggcaaaca aatacgatta aaaaaagaaa caatgaatga
    35641 atcgattacg attgtaagga gtgaacaact agatggcata tccgattaaa tatatggaag
    35701 ataatctcgt atttaatcat gatggcgaag tattcgctta ttatgaatta attccctata
    35761 attacagttt tttaagttcc gatgaaaaaa ttcaagttca tgataatttc tgtcaattga
    35821 ttgcccaaaa tcgtgatggc aagattcatg ctctgcaact agcaaccgaa tcaagtattc
    35881 gagccacaca ggaacaatcg aaaaaagaaa tcactggacg attaaaagag atagcttacg
    35941 aaaaaataga tgaacagacc gaagcgttaa tttctatgat tggtgacaat caagtagact
    36001 atcgcttttt tattggtttt aaactctacc tcaatgaaca ggaagtatcc gtaaaaaatg
    36061 ttgggaaaga aattcaaaaa gcatttgcgg aattctttca tggtgtgaat cacaaattaa
    36121 tgggcgattt tgtttctatg cctatggcgg aaatcgaacg cttttctaag atggaacagt
    36181 tgttagaaag taaattatcc agacgctttc agattcgtaa attggagaaa gatgattttg
    36241 gttatattat tgaacatctt tacgggcaaa caggtgtccc ttttgatgac tacgactacc
    36301 atttaccgaa acgatacgaa gataaaaaag tgttggtaaa gaaatacgat attctcaaac
    36361 ccactcgctg tttaatcgaa gaaaatcaac gctatttacg gattgaacag gaagatacca
    36421 ctacttatgt ggcgtatttt acaattaata gtattgttgg tgaattggat ttccctaata
    36481 gtgaaatttt ttattaccag caacagcagt ttactttccc cgttgatacc agtatgaatg
    36541 ttgaaattgt cgccaataaa aaagccttat ctaccgttcg caataaaaag aaagaactga
    36601 aagatttaga tagccacgca tgggaaagcg acaacgaaac cagtactaat gtggtggacg
    36661 ctttagaatc tgtcgatgaa ttagaaagta atttagacca aaccaaagaa tctatgtaca
    36721 aactaagcta tgtggtacgg gtatcagcaa agaatttgga cgagctgaaa caacgttgtg
    36781 atgaagtaaa agatttttat gatgatctgt ctatcaaatt agtacgacct tttggcgata
    36841 tgctaggctt gcataatgaa tttattccct caagcaagcg atatatcaat gactatattc
    36901 aatatgtcac gtcggatttt ttggctggtc ttggtttcgg tgctacacaa atgattggtg
    36961 aaaattctgg tatttacgtc ggttacaatc tcgatacagg cagaaatatt tatctccaac
    37021 ctagccttgc aagtcaagga attaaaggct ctgtaacaaa tgcattagcg tccgctttta
    37081 ttggttcatt aggtggcgga aaatcattct ctaacaatat gctggtctat tattcagtac
    37141 tctttggcgg acaggcaacc attgttgacc caaaagctga acgtggtgaa tggaaagaaa
    37201 ccttacctga tattgcccat gaaatcaata ttgttaatct cacgagtgag aacgacaata
    37261 aagggttact tgacccttat gtgattttaa aactcccgaa agattcagaa agccttgcca
    37321 ttgatattct cacgttctta acaggtattt ccagccgaga tagcgagaag tttcctgtcc
    37381 tgcgtaaagc tattcggagt gtaactcaaa gcaaacaacg agggttgtta ttggtgattg
    37441 atgaattgcg aaaagaagat acgcccatca gcaatagtat tgctgaccat atcgaaagct
    37501 ttgtcgatta tgattttgcc catctgttat tcagtgatgg cagtgtcacc caatccatta
    37561 gcttggaaaa acaactcaat attattcaag tggcagattt ggtcttaccc gattccaata
    37621 gctcttttga agaatacact accatggaat tattaagtgt ggcaatgctg attgtcatta
    37681 gtacctttgc tttagacttt atccactctg accgttccat ttttaaaatt gttgaccttg
    37741 atgaggcttg gagtttttta caagtggcac aaggaaaagc tctatctatg cgattggttc
    37801 gagcaggacg tgccatgaat gcaggggtct atttcgttac tcaaaacgcg gacgatttac
    37861 tagatgaaaa gatgaagaat aatattggct tgaaatttgc ctttcgttcc actgacctag
    37921 tggaaatcaa aaagacctta gaattttttg gtgtggacaa ggaagatgaa aacaatcaga
    37981 aacgcttacg tgaattagaa aatggacaat gtttagtttc agacatctat ggtcgtgtag
    38041 gggttatgca gtttcacccg atttttgaag agttgcttca tgcctttgat accagaccgc
    38101 ctgtgcgaaa tgaggtggaa gaatgacaca aaaacaaaag aaatttcttc actatagttg
    38161 gataacgctc ctttgtgtgg gcgttatttt acttttatta ggcacgctgg gcaatgcagt
    38221 acaagcgaca ggcttagttg atgaaaccat tgatacaagc aatgaatact ccaagtatgg
    38281 tttgaatcaa tatcagcttg attattatgt ggacaatagc tggggctggc ttccatggaa
    38341 ttggagtgat ggcataggac aatcggtgat gtatggattg tatgccatta ctaattttat
    38401 ttggacaatt tctctttatc tatcgaacgc cacaggttat ttggtgaaag aagcctatgc
    38461 cttagatttc attagtcaaa catcccaagc aattggcgaa aacatgcaga cgattgcagg
    38521 cattacaccg aatggctttt ccagttcagg gttttatgtc ggtttcctcc ttctttttat
    38581 tctcattgtt ggaatctatg ttgcctatac aggattggtt aagcgagaaa cgacgaaagt
    38641 gatacgagct gttttaaact ttgtcgtggt gtttattcta tcggcttcct ttattgcgta
    38701 tgcacccgat tatattgcga aaatcaatga tttttccaaa gatgtcagta ccgccagtct
    38761 gaatattggg acaaaaattg ttcttcctaa cacggatagt caagggaaag acagtgtgga
    38821 catgatacgt gacagcttat tctctgttca agtaaagcaa ccatggctat tgcttcaata
    38881 tggctccact gatgtagaag cgttagggga agaacgtgtg gaaagtttat tgtctaccag
    38941 tccagataca aacaatggtg aagatagaga aaatgtagtg attgaagaaa ttgaagatca
    39001 tgacaatacc tatttaaccc taccgaagac gatttccaga ttaggaacag tcttcttttt
    39061 gtttgtattc aatattggta tctcgatttt tgttttcctt ctaacaggaa tcatgatttt
    39121 ttcgcaagtg ctatttatta ttttcgctat gtttttgcca atcagtttcc tattaagtat
    39181 gttgccgagt tttgatggca tgggcaggca tgccattacc aagttattta atgtgattat
    39241 gacaagggct ggtattacct tgattattac cgttgccttt agtatttcca ctatgcttta
    39301 ttcgctgtca gcaagttctc cctttttcat gattatgttt ttacaaattg tgacctttgc
    39361 agggatttat tttaaactgg gcgatttaat gagcctattc actttacaaa gcaacgactc
    39421 tcaaaacatg ggcagacaag tgtttcgcag acctcgtcaa atgatgaatc gacaaaccag
    39481 aagatttcaa cgcagtatga gtaagatttt tcgtggaaaa gcagggtcaa cgaagcaaaa
    39541 gacaatgaca acaaagcaga atcaaaccaa taaagctaac catactcgtc aaaatgaacg
    39601 gactacacca aagaaagaaa cagcactttc caatgtgaaa aagcaacaag gcggtatcgg
    39661 gcaacgatta ggtgaaaaga cagcccatgt attggacacg aaaaatcgtc tagtcaataa
    39721 aagaaagcag gcaaaacaac agatacaggc gacaccaacc catgtcaaat atgcccttca
    39781 tcaaggaaaa gagaatgtca ctcataatgt aacagacttt aaacaatcta tggcagatac
    39841 caaagctcaa cgcaaacaac agcgtatgaa ccagcaggag caaaaacgaa agaacattgc
    39901 tcaaaagcgt ttggagctgg ataaagcaaa agaaaaaaga cgaaaagaaa acccatcatc
    39961 tcctgttcag aataaccagc agcatgttcg caagcgtcag caaaccgtca cgcctgtttt
    40021 gtcacaaaac actaaacgtg aaaatcatca gcgaccattg aaaaaagagc aaaaacaaaa
    40081 gacaccaccg aagcaattca atcagaggaa gctaaataaa agaacggata agcgaggaca
    40141 acaaacatga agctaaaaat aacagtgatt tgtagtgtgg tcttctctct cttctttttt
    40201 ctcttattat tcctagtcat tttctttgca gatgatacgg acagtggcga aaacaacaag
    40261 gattcttcta ttccacaagg cggtgtgacc gtttcaccag aagtgttggc acaccgtccg
    40321 ttgattgaaa aatatggtaa ggaatatggg attgaagact atgtttctta tatcttagcc
    40381 attatgcaag tggaatcggg cggtacagca gaagatgtta tgcaaagttc cgaatctttg
    40441 ggtttaccgc ccaacagttt gagtaccgaa gagtccatca aacaaggggt taaatatttc
    40501 agtgaattat taaccagtgc agaacaacaa ggagtggata tagattctgt tatccaatct
    40561 tataattatg gcggtggctt tttaaattat gtgaggagtc atgggaaaaa atatacctat
    40621 gaattagccg aacagttttc taaagagaag tcgggtggtc aaaaagcaga ctatcccaat
    40681 cctatagcca tacctgtgaa tggtggttgg cgatataact atggaaatca gttttatgtt
    40741 cagttggttt cacaatacct aaccgacact tccccaacag aatttgatgg tgaaaccgtg
    40801 caagtcatta tggacgaagc cttgaaatac gaagggtttc cctatgtctt tggaggggcg
    40861 tcgcctacca cctcttttga ttgtagtggc ttaatacaat gggtgtatga caaagctggc
    40921 atttctctcc ctcgtgtcgc ccaagatcag tatgacgcta cgcaagaaat ctctatggaa
    40981 gaagcccaag caggcgacct tatcttcttt cattcaacct ataatgcagg cacatatgtg
    41041 actcatgtgg cgatatattt agagggaaat cgcttttatc atgcaggcga cccaatcggt
    41101 tatggcgact taagcagtcg ttattggcaa gaccatctga ttggggctag acgtgttatt
    41161 cataactaag aaaggaatga atcaaatgat tataaaaatc gagcgaaaag aaaagaagga
    41221 gaaaccaaag aaatctaaaa aaccgagcaa gcaaagaaaa gttccgatga ttaaagttgg
    41281 cacgcataag aaattaacct ttgttttatg ggttttattg attggtagtg tcggatttgg
    41341 aatctataaa aattttactg ccattgacac tcatactgtc cgtgaaacag aaatcattaa
    41401 acagcagatt gtcgatacca accaagtaga aagttttgtg aaatcctttg cgaaagacta
    41461 cttttcgtgg caacaatccc aagaagccat tgataaacga aatgaaaaat tgacccatta
    41521 tttgacggaa gaattgcagg tattaaatga agaaatgatt cgtaaggata ttcctactag
    41581 ttctagtgtg aacgatatac aggtgtggca ggtttctcaa gtgaatgaga acacctttga
    41641 ggtactgttt tctgttgaac aagttattac cgaagacaaa gacaaggaaa ctatatcgtc
    41701 tagctttcat gtggttgtcc atatagatga atcagataat atggttatta tcaaaaatcc
    41761 gacaatgagt aagaaacctc aaaaatcgga ctaccaaccc aaacagctag aaagtgacca
    41821 tacagtagat acagaaacga tggacgaaat cactagcttt ttagaaacgt tcttccagct
    41881 ctatcctacc gccacagaaa aagaattgac ttactatgta agtaatcatg tgttacctat
    41941 gattaacaag gaatatgttt tcgaggaatt ggtgaatcct atctttacca gaaaagataa
    42001 ccaagtaatc gtgaatgtcg ctgtgaaata tttagatcaa gaaacaaagg caacccaaat
    42061 ctcgcaattt gagttgatat tagaaaaaca agataattgg aagattgtaa aataacaaat
    42121 attggtacat gattacagat actttgtaat catgtactct ttttgataaa aaattggaga
    42181 ttcctttaca aatatgctct tacgtgctat tatttaagtg actatttaaa aggagttaat
    42241 aaatatgcgg caaggtattc ttaaataaac tgtcaatttg atagcgggaa caaataatta
    42301 gatgtccttt tttaggaggg cttagttttt tgtacccagt ttaagaatac ctttatcatg
    42361 tgattctaaa gtatccagag aatatctgta tgctttgtat acctatggtt atgcataaaa
    42421 atcccagtga taaaagtatt tatcactggg atttttatgc ccttttgggt ttttgaatgg
    42481 aggaaaatca catgaaaatt attaatattg gagttttagc tcatgttgat gcaggaaaaa
    42541 ctaccttaac agaaagctta ttatataaca gtggagcgat tacagaatta ggaagcgtgg
    42601 acaaaggtac aacgaggacg gataatacgc ttttagaacg tcagagagga attacaattc
    42661 agacaggaat aacctctttt cagtgggaaa atacgaaggt gaacatcata gacacgccag
    42721 gacatatgga tttcttagca gaagtatatc gttcattatc agttttagat ggggcaattc
    42781 tactgatttc tgcaaaagat ggcgtacaag cacaaactcg tatattattt catgcactta
    42841 ggaaaatggg gattcccaca atctttttta tcaataagat tgaccaaaat ggaattgatt
    42901 tatcaacggt ttatcaggat attaaagaga aactttctgc cgaaattgta atcaaacaga
    42961 aggtagaact gtatcctaat atgtgtgtga cgaactttac cgaatctgaa caatgggata
    43021 cggtaataga gggaaacgat gaccttttag agaaatatat gtccggtaaa tcattagaag
    43081 cattggaact cgaacaagag gaaagcataa gatttcagaa ttgttctctg ttccctcttt
    43141 atcatggaag tgcaaaaagt aatataggga ttgataacct tatagaagtt attactaata
    43201 aattttattc atcaacacat cgaggtccgt ctgaactttg cggaaatgtt ttcaaaattg
    43261 aatatacaaa aaaaagacaa cgtcttgcat atatacgcct ttatagtgga gtactacatt
    43321 tacgagattc ggttagagta tcagaaaaag aaaaaataaa agttacagaa atgtatactt
    43381 caataaatgg tgaattatgt aagattgata gagcttattc tggagaaatt gttattttgc
    43441 aaaatgagtt tttgaagtta aatagtgttc ttggagatac aaaactattg ccacagagaa
    43501 aaaagattga aaatccgcac cctctactac aaacaactgt tgaaccgagt aaacctgaac
    43561 agagagaaat gttgcttgat gcccttttgg aaatctcaga tagtgatccg cttctacgat
    43621 attacgtgga ttctacgaca catgaaatta tactttcttt cttagggaaa gtacaaatgg
    43681 aagtgattag tgcactgttg caagaaaagt atcatgtgga gatagaacta aaagagccta
    43741 cagtcattta tatggagaga ccgttaaaaa atgcagaata taccattcac atcgaagtgc
    43801 cgccaaatcc tttctgggct tccattggtt tatctgtatc accgcttccg ttgggaagtg
    43861 gaatgcagta tgagagctcg gtttctcttg gatacttaaa tcaatcattt caaaatgcag
    43921 ttatggaagg gatacgctat ggttgcgaac aaggattata tggttggaat gtgacggatt
    43981 gtaaaatctg ttttaagtac ggtttatact atagccctgt tagtactcca gcagattttc
    44041 ggatgcttac tcctattgta ctggagcaag cctttagaaa agctggaaca gaattgttag
    44101 agccatatct tagttttaaa gtttatgcac cacaggaata tctttcacgg gcatataacg
    44161 atgctcccaa atattgtgca aatatcgtaa atactcaact gaaaaataat gaggtcatta
    44221 ttattggaga aattcctgct cgatgtattc aagattatcg caatgattta acttttttta
    44281 caaatgggct tagtgtttgt ttagcagagc taaaaggata tcaggttacc actggcgaac
    44341 ctgtttgcca gacccgtcgt ctaaatagtc ggatagataa agtaagatat atgttcaata
    44401 aaataactta gtgcgtttta tgttgttata taaatatggt ttcttattaa ataagatgaa
    44461 atattcttta atatagattt gaattaaagt ggaaaggagg agattgttat tataaactac
    44521 aagtggatat tgtgtcctat ttgtggaaat aaaacaagac tacgaatacg agtggatact
    44581 atacttaaaa atttcccttt atactgcccc aaatgtaaga acgaaacttt aattaatgtt
    44641 caaaaaatga atataataac aatcaaagag ccagacgcca agacgcagag ccgataattt
    44701 gagaaatgaa actctcatct tatcggctct ttttgtttat ctgaatttta ctgactagcc
    44761 ttcaatattt cttgcttcat tgataccttt tgctagtgct tccattaagg atagttcttt
    44821 gtctgtaaag ctatccatgt atttttctac ctgtaacctt cgagtgcttt taatcaaatt
    44881 atctgtaggt aagaaaaatt catcaataga tacatggagt aatgatacaa gatcatacag
    44941 cacttgtgta cttgggtgtt gtcctttgtt ttctatattt gttaaataac gtgggtcaat
    45001 ttcaatcatt gttcccactt gttcacgagt gagaccccgt ttcattcgag cctctttaat
    45061 cgctaaacca acggctctaa aatcgtattt atcttctttt ttacgcatac taaatcacct
    45121 ctatacattt tactgttcct atataaccat aaacaggtat agaaaaacat gttatatagt
    45181 ttatgagttc ctatagaaca ctgtggaatt tattaatgcg atgaatccaa tttcaaatag
    45241 aaaggtcgct gattttattt acctatacaa ctttataaaa tttagtcata ctcctagaaa
    45301 gtagataaaa ttggcgactt aatggaggga aaagtcgcca tgagaaagat aatctgtcat
    45361 ctagttctct taattaagtt cttatcaaaa aaacttatcc acctgtactg gatagatatg
    45421 accatcaatg tggttttgca gattacatag atagaaaaat caaagcatat gaacagagaa
    45481 aacaatctgt ttatgtgctt ttttggtcac ttaataaata tcttttagga tttctcttca
    45541 tttatgcaac aaatccccct ttcgtgtcgg ggtttagtat gaagggagat aaagaagcac
    45601 atgccactcc ctttcacgac agaaaggggg tgaaaagcat gaaaccatct tcttttcaag
    45661 aaaccataga aaatcagttt gactatatct gcaaacaagt tattgaagat gaacgaaaag
    45721 attacttcaa acatctagac agactatcag caaaagaagt ctcgttttct gatatagata
    45781 actaccttgt caactctttt tctactgttg atacgtacgt cactgatttc caactattta
    45841 aattatttgg attaagaatc aatgttgaaa gtgatttatt aagtgaagcc ctgcgtcatc
    45901 tttcagagaa aaaacggaac attattttac ttcattactt tatggatatg agtgatgtgg
    45961 agattgcgga gttactaaat ttgaatcgtt cgactgttta tcgtcatcga ataagtggac
    46021 tagccatgat taaagaattc atgaaggagt gtaaagaatg aaaacagctt atccaagggt
    46081 tcccttcccc ctcattgtaa aggcgacaga tggcgacgtg gaagcaatta atcagattgt
    46141 taaacattat cgagggtata cctcaaaacg ttcattacgt cgcatgacag acgaatatgg
    46201 aaattctcat atggttattg atgaaaccct acgtggcaga atggaaacga aactcatctc
    46261 taagatttta tcgttcgaaa ttaaatagtc ccattttttc gtggaagcgt gtcgaatcgt
    46321 atccacgctt cccgatttgg gaggtttgtt attccatcaa agcatattgt gtgttcagta
    46381 ggttttgata ggctaacaag ccaaacgttc tttgacaacc aaataaaggc aatcgaatac
    46441 gtttcggtaa gaaaagagct gatgaactaa cacgccatga cctacaaaat tagtgagcga
    46501 ttcatgttag taattcgaaa gtaatcttta gcaggattgc tgccatgact ttcttatcgt
    46561 gataatgata ctcccgtata gccatagtcc gagcgttaga agcgtcacag gcaatgggta
    46621 cggctacatg agaaccatgc agaagtgaaa ttcctgtgag ctttgctaga gctgttcgat
    46681 tgctaagata ttcttctctt gtcagtgtat tattataaaa ctatttgata taattatagg
    46741 tgaatattgg agttttccta gcctataatt gggaaaggag taataatgat aacggtcaca
    46801 aaaaaggatt tagttgagct aggatatgga acttcttttt cagcagacat cataaaaaaa
    46861 gcaaaagaat tgatgattac aaaagggcat atctactatc aatctcgaaa gctagataga
    46921 gtccctcgtg aagctgttga agaaattcta ggaattcggt tttcaaatga aaacaggtct
    46981 gagtagtttt tgcacagtaa ggagtaaaaa ctatggttaa agacccaata aaaaaagcaa
    47041 agaatggaac ctattatttt cgtgcaaatc taggttatga ttctaaaggg aaaaaaattc
    47101 aaaaatatcg tagtggattc actactaaaa aagaagcaag agaagaatat tcgaaactgc
    47161 tattgatgaa accagaagaa ttaagtgaga ataaggataa aatgacgttt aaacattata
    47221 tctttgaaat tttccttcca tggtataaga cacaggtaaa gctcagaaca tatgaaaatc
    47281 gcttaccaac tattaagaag catttctctt attttgataa aatggctgtt tccgatattg
    47341 agcctattga tgtgcaaaat tggcaactaa aattatcaaa gaagtgtaag tcttcttatg
    47401 taagagctgt tcaaggacta ttttcagttg ctatggatcg agcaattgtc cttgggataa
    47461 ccaccacaaa tccatctaag attattggca atgtgaaaaa gcaaaagtct aaaattgaat
    47521 tttggacaaa agaagaattt gaaaaagtaa tctctctaat ttacaaagaa gattactatc
    47581 aacacttttt atttatctct ctgtggtttt tatttatgac tggaatgcga attggtgaag
    47641 ctactgccat tcaatgggaa gatattgatt ttgactcagg agtactaacc atcaacaaaa
    47701 cactctatta caagaatcaa tcgaattata gatttgttga accaaaaaca aaggcgagcg
    47761 ttcgtcatat tgtattagat aaatgcacat taacttattt atccgaatgg aaggaagtac
    47821 aacaaaatct aattcagaca gactttgtaa tgagctataa cggtattcct acccaaaaac
    47881 atacactatc atatgctatt gaacgctatg ctaagctggc tggtatccat cgaatcagaa
    47941 tccatgggtt acggcattct catgcttcct tgttaatcag tatgggagaa aatccactta
    48001 tcattaaaga tcgtctagga cacgaagata ttgagacgac tttaggaacg tatggacatc
    48061 tttatcctaa cagtaatttc gaggtagcta acaaattaaa tggagccatt tcctttaaag
    48121 aagcaaaaca aaattatgat acttcaccaa agaatcaatt tactgtagac tacttgcgaa
    48181 acaaagaaat gaaaaaagtg caataaaagt gcagtaaaaa gataagaaga gccagaaacc
    48241 cttggtataa gaggatttct agctctccta caactattcc cactccactg ttgctggtgg
    48301 tttagaagtg atgtcataca cgatacggtt gacgtgggct acttcgttta cgatacgtac
    48361 agagattttt tgcaagactt cccatgggat acgggcaaag tcagcggtca ttccgtcgat
    48421 tgaagttaca gcacggatac cgactgtgta gtcgtaagta cgtccgtcac ccataacacc
    48481 gacagagcgg atccctggaa gaacagtgaa atattgccag atatcacggt caagtccagc
    48541 agctgcgatt tcttcacgca agatagcatc agattcgcgt acgatttcta gcttgtcttc
    48601 agtgatttcg ccaagaacac gaataccaag accaggacca gggaatggct gacgccaaac
    48661 gattgaatca ggcatgccta actgagtccc taattcacgg acttcgtctt tgaataatgt
    48721 gtttaatggt tcgatcaatt caaattgcat atcttctggc agtccaccta cattatggtg
    48781 agatttgatc gtctgtgctg tttctgtacc agattcgata acgtcagtat acaacgttcc
    48841 ttgtgctagg aaagagacgc cttcttcacc agcaagtttt gttgcttcgt catcaaaaac
    48901 atatacgaat tcattcccaa tgattttacg tttttgttct gggtcagata cacctttcaa
    48961 cttgtctaag aagcgatctc ttgcatcgac tttgatgatg ttcaagccga attttccgcc
    49021 tagactttcc attacttgtt ccgcttcgcc tttgcgtagc agaccgtggt caacaaagat
    49081 agatgtcaat tggtcaccga tcgctttttg taaaagaacc ccaacgacac tagaatcaac
    49141 gccacctgaa agaccaagca agactttttt gtcaccaact tgttcacgga ttttttctac
    49201 ttgcatatcg ataaagttat ccattgtcca gttaccttca cagtgacaaa catcaaaggc
    49261 aaagtggcgc agcaattcga ttccgtattc ggaatgacgt acttctgcat ggaattggat
    49321 accataaaaa ttacgtgttg tgtcttggat agaagcaatc ggacaatctt tgcttgttcc
    49381 gactgtttca aagccttcag gaactttagt taccaagtca ccatggctca tccatactgt
    49441 ttgttgtttt ggtgtttctt taaacaagac agcttgatcg cttgttactt ctaacaaggc
    49501 tttcccatat tcgcggtttt tagcaggctc tacggaaccg ccaagtttgt acgtgatcaa
    49561 ttgcatacca tagcaaatcc ctaatacagg aatacctaaa ttgaagatct caggatcgat
    49621 cccaaatgca ttctcatcat atacactgtt tggtccgcca gaaagaatga ttccctttgg
    49681 attcatcgct tttacttctt ctgcagtaat gcggtggctc aataattcgg aaaagactcc
    49741 aagatcacga atacgtcttg tgatcaattg gttatactga ctaccgtagt ctaatacgat
    49801 aatcttttca acgttcgtca tatcggcaac gtttgtcaaa tttattaccc ctatcccttt
    49861 aaattttatc tcaaaatagt caaactattt taaaatgcta atattttcgc atgaaaatcg
    49921 aatcgatgat atgattttca gttttatgga gaattatatc ggctcttcct cgtgtaggca
    49981 agatatattc ctgtaaattt ttcaaattca catttttcca tacatctttt gccattttaa
    50041 aggcttcttc acgatctccg atagcaaaac gataataata attctctgga ttttggaaag
    50101 ccgtatccag taacgcacca aaacgatcca aataccattt ttcgatcagc acgggatcgg
    50161 catcgacata gacagaaaaa tcaaaaaagt cgctgacgta gatttgctga ttcgcaggta
    50221 attgaagcgt attgatcccc tcaacgatca agatatcagg ctgctggatc aattcgtact
    50281 tgtctggaat gatatcatac acatcatgtg agtaaacagg tacttttatc tcttcctgac
    50341 cagattttac acggttcaag aaatcgatca gcatctccat atcataactt tcaggaaatc
    50401 ctttacggtc catgattcca cgctctttta atatacgatt tggataaaga aatccgtcag
    50461 tcgtgatcag ctgaacgttt cttcgtttga aggtacgaga caaaatcgtc tgcagcagtc
    50521 tggctgttgt actttttcca acggctacac ttccggcgat cccgataata aaaggcggta
    50581 cttctacgta tttatgaaga aataaacctt tactcaagaa caaagattca aattctttca
    50641 tataaagata aatcagatga gcaagaggta catagatatc tcgaacatcc tgcatggaaa
    50701 tgcggtcatt caaacttttg atattatcta gttcatcttg tgtcaaaggt gcttgcccat
    50761 tacgataaaa ttctcgccat tcttctcttg ccacacggta gtagttcatt ggatcattca
    50821 tattagcctc ctgcgttctc ccatcaatgg aactatttta acacaaaata aacgcaaacc
    50881 ccaccactta agagagattg ccgatctttt tgtataatct ttataataga aagaaacgga
    50941 gtcttattct tgacttgcgc acggatacat aaaaggatag actgttgtca tgaaagaaat
    51001 gagaaggatg gaagacatga caaatcatta ctattctgaa cgcccagata cggcgcacga
    51061 ttttgaacaa tgggcttttg agttaaaagg cagaaccttt caatttgtaa cagattctgg
    51121 tgtattttca cgtgaaacag tggattatgg ttcacgtgtc ctgattgatg ctttcgattg
    51181 ggaagagtta cctgatgaag gaaagatctt agatgtggga tgcgggtatg gaccgattgg
    51241 gttagctttg gcatttgcga cacagcggtt tgttgaaatg gtcgacatta atgaacgagc
    51301 ggtaagtcta gcgcaaggaa acgcaaagcg taaccaaatc gaacatgttg atatccatca
    51361 atcgaatatc tatgaagcag ttcatgaaga aacctatgca gctatcgtaa gcaatccgcc
    51421 gatccgtgct ggaaaaaaag ttgtacatga aattttgaca ggcgcatatc ctcggttgaa
    51481 gaagggcggt acactgacaa ttgtgatcca gaagaaacaa ggagcgccga gtgcgcaaaa
    51541 gaaaatggaa gaaacatttg gtaatgcaga aatcgtcaca aaagataaag gatattatat
    51601 catcaaaagt gtgaaagaat aactagctga aaaatagtgg agcgacgaaa gagtggaact
    51661 gggcgtgcat gtacgggtac gtatcagttc tttttttgtt gagaagtttt taaaaacaaa
    51721 gaactatttt ttcttcaaaa agaaatagta ggaacagagt cgttgttttt tacgataaaa
    51781 taaataagat acagaacttg tatagaaggc tgccaagtcg gtagataaag gaggttttta
    51841 tcaaaaaaca tactttcctt ttttctctat tcttttcttg ggggttttgg tacactgata
    51901 gggaatttag atagaaggga gccaatagga tgaagctgac catcagagat atcgcagaaa
    51961 tggcaggcgt atcagtaaca actgtctcac agattttgaa taacaaagga agcagattta
    52021 gtgataagac aagaaaaaaa gtgttgtcga tcgtgaatga acatcattat aagcccgatt
    52081 atttcgcttc aaatgtgatc aatcgacatt caaagaccat cggaatgatc gtccctgatg
    52141 tcactgattt cttcttctcc aaactgatcg aaggtgtaga gagctatttg aatcctttgg
    52201 gctatgtgat catgttatgc aattctcgtc atagccaaga aaatgagatc aagtatttac
    52261 aagagctttc ccaccgctca gtggacggaa tcttgctggc cacaccaaat attttacctg
    52321 agaaatatgc attagacagc ggtttttatc aaaaaatgcc aatcatttta atcgatcgcg
    52381 gattgaatcg tcgggataac ggacggctta tcgtaaagga atatgagggc gcctatcaag
    52441 ctgtttcgct gtttattgaa aatggccata cgaagatcgg catgctgaag gaaaccactg
    52501 gatactatca attagaagaa cgtttcaacg gatatcgtca tgcgctgaaa gatcatggcc
    52561 tgccttttaa tgggaaattt gttgaacatg gagagttgac tgtccaaggt ggatatactg
    52621 catcaaaaaa attactcaaa cataaagata tcacggctat tttttgcggg aatgatgcca
    52681 tggcgatcgg atgctatcag gcgatcgatg aattgggcaa aaaaatccca gaagatatct
    52741 cagtcatagg attcgatgga ttaaagctgt cagaatacat gattccgcaa ttgacgacag
    52801 tgcagcagcc aagttttgat attggatttt atgctgcacg tttcctgatc gatacgatcg
    52861 aatttcctca aagaaaagtt ccgaacaaag tgttcgaaac aaaattaatt attcgtgaga
    52921 gcgtaaaagt attgacaaag ggctaactcg gcggtatatt gcttatgtaa gcatttacaa
    52981 aggctagtta gtgctttttt tatttttagt aaaccagttt actaaagtgg tttacctttc
    53041 ctaaaaataa tgtataatac cgaatgaaga caaggaggat caggcaatgc gaatggtgga
    53101 tctgattgaa aaaaagaggg atggaaacga gctgtcgaaa gaggaaatcg agtacatcgt
    53161 cacgaactat acgaatggaa agattccaga ttatcaagtc agtgcattat tgatggcaat
    53221 tttttatcaa gacatgacaa atgaagaaat cacgaactta acattggcga ttgctaattc
    53281 tggtgatgtc atcgatttga gttctcttga aggaataaag gtagataagc attcgacagg
    53341 tggcgttggt gacacgacca cattgatttt agccccccta gtagctagtg tcggagtgac
    53401 agtggctaaa atgtctggac gcggtctagg ttacacaggt ggtacactag acaagctaga
    53461 agcaattccc ggatttcaga tcgagctttc ggatgaagaa tttgtacgca ttgttaatga
    53521 aagtaaagta gcggtaattg gtcaatcagg aaacttggca ccggcggaca aaaaattgta
    53581 tgccttgcgt gacgtcacag cgaccgttga ttctcttccg ctgattgcca gttcgattat
    53641 gagtaaaaaa atcgcggcag gagcagatgc aatcgttttg gatgtgacca ctggagacgg
    53701 tgctttcatg aagaacatcg aagatgcaag acgtctggca aagaccatga cgagcattgg
    53761 gaaactggct aaccgagaaa cagtggcggt tatctcagat atgtcagaac ctcttggcga
    53821 agctatcgga aatagtctag aagttgtcga ggcaatcgaa acattacaag gaaatggtcc
    53881 agaagatcta gtagaaatgt gctacgcctt aggaagccaa atggttgttc ttgctggcaa
    53941 agctaagaca accgatgaag caagaacgtt gcttcaagaa gctctggaat caggtaaagc
    54001 gttagcaaaa ttcaaagaaa tgatccaaaa tcaaggggga gacccagcga tcgtggaaca
    54061 tccagaacga attttgactg cacgctacac aatggagctt cctgctaaac aaagcggagt
    54121 tgtgtcaaaa atcgtggcaa atgaattagg aattgctgca atgatgctag gtgctgggcg
    54181 taaaaccaaa gaagaagata ttgatcacgc tgttggattg aaactgcata aaaaaattgg
    54241 tgacactgtg acaaaaggtg agtcactatt gacgatctat agtaacgacg aagaaatcac
    54301 ttctgtcatt gaattattat ataaaaatat tgaaattggt gaatcggcaa tgaagccaac
    54361 gttgattcat gacatcatca cagaataaag gaaaaaagcg gactttaccg ttttaaagaa
    54421 aaggggaaaa gaaatggaac taaaccgaat gatcgaccat actattttga aagcagacgc
    54481 atctaaagaa gctgtgatgc aaattatcga agaagcaaaa aaataccatt tttattctgt
    54541 ctgcatcaat ccagcatggg ttgcgctagc gaaagaacaa ttacaaggtg agccagtagc
    54601 cgtatgtaca gtaatcgggt ttcctctagg agcaaacaca cccgagacaa aagcatttga
    54661 aacaacagat gccatcaata acggtgcaga tgaagtcgat atggtcatca atatcggtgc
    54721 tttgaaatca aaggatgatc aacaagtcca aaaagatatc gaagcagttg ttgaagcagc
    54781 aaaagatcgt gcgcttgtca aagttattat tgaaacatcg ttattagata gagaagaaat
    54841 catccgagct tgcgaaatag caaaagctgc aggcgctgat tttgtcaaaa catcaactgg
    54901 tttctcaaca ggcggagcaa aggtagagga tgtccgtttg atgcgtgaaa ctgtaggacc
    54961 agaaatgggt gtcaaagctt ccggcggtat ccataacgaa gaagaagcaa tggcaatgat
    55021 cgaagctggt gctacaagaa tcggaacaag cgcaggagta gcaatcgtat ctggttcaac
    55081 tggtgaaggc tattaatttt ttcaaaggag aagctcatgg cagaactcaa acaagaatgg
    55141 atcaacacag ctattgaagc gttagataaa gcctatgttc cttattccca ttttccggta
    55201 ggcgcttgtc tcgtaacgga atcaggcaag atttatcaag gcatcaacat tgagaatgca
    55261 tcatttggat taacgaattg tgccgagcgc acagcttttt tcaaagcagt atctgaagga
    55321 gaaaaaacat ttacgcatct agtcgtagcg gggcacaccc ccgatcctat ctctccttgt
    55381 ggtgcatgtc gacaagtaat ggcagaattc tgttcccctg atatgccggt tacgctagta
    55441 ggagacaatg gtgtgacgaa ggcaacgacc gttcgtgcac tgctgcctta tgcatttact
    55501 gaaaaagatc tataactcat gttcattcag tcagctgact gttgaaaaat aaaacaatta
    55561 ttttaggagg ctttacagaa atgaaaaaag caaaattatt tggtttaggt gctgtcgcac
    55621 tagcagcagg gttattttta ggtgcatgcg gcaacaacgg ctctactgat tcatccggtg
    55681 gcaaaagctc atcagacaca acaactgcag cattgatcac agacacaggt ggtgtagacg
    55741 accgttcatt caaccagtca gcttgggaag gactagaaaa atgggggaaa gatcaaggac
    55801 tttcacgagg aaatgatggc ttccaatatt tccaatcttc aaatgaatca gattacatcc
    55861 caaatattga ccaagcattg aatgctggat tcaaaacgat ttttggtatt ggttataaac
    55921 taaaaccagc gatccaagaa caagcaacaa acaatacagg tacgaacttt gttattatcg
    55981 atgatgtcat cgatggatta gataacgttg tatctgcaac tttcaaagac aacgaagctt
    56041 cttatcttgc aggtgttgca gcagcttata cgactgaaac aaacgtagtc ggctttatcg
    56101 gcggtgtaaa aggtgaagta atcgatcgtt ttgatgctgg attcaaagcc ggtgttgatg
    56161 caggtgcgaa agaattagga aaagaaatca aagtattgaa tcaatatgct ggtgacttct
    56221 ctgctccaga taaaggacgt tcaattgctc aaggtatgta tgcacaaaac gcagatatca
    56281 tcttccatgc ttcaggcggt acaggtaacg gtgtattcca agaagcaaaa tcattgaacg
    56341 aatcaggcga caaaaaagtt tgggttatcg gtgttgaccg cgaccaatca gacgaaggcg
    56401 aatacacatt aaacggcgaa aagaaaaact tcacattgac atctacactg aaagcagttg
    56461 gaacagtagt agaagatttg gcacaaaaat cagcggacgg taaattccct ggcggcgaac
    56521 acactgttta tggattgaaa gaagacggtg ttggtctaac agaaggacaa ctttctgacg
    56581 aagcgaaaaa agcagttgat gaagcaaaag aaaaaatcat ttcaggtgac gtaaaagttc
    56641 cagaaactcc tgaagaaaac taaaaccatt tctatagcct tgttagacac atgtttgaca
    56701 aggctatggt ttgattagaa caagaattgt tcatttatcc aagctgcctt gtgacagttt
    56761 ggataaggga acaactccct gaagtaatgt ttgtttcaaa agaagaacgc tcactaagcg
    56821 tgaatcttag tcaatcgttg ccctagatag aaatcgttag gatgtgaaaa aaaggtggtt
    56881 caagaaaata ttgtcataga aatgcagaat attaccaaag aatttggaac attcaaggca
    56941 aatgacaaca tcaatttaca agtaaaggca ggagaaattc atgcgttgct tggagaaaac
    57001 ggtgctggca aatctacatt gatgaacgtg ctttccggat tattagagcc gacatcaggg
    57061 aaaattttga tgcgtgggaa agaagtaaag atcacaagtc cgaccaaagc caaccaatta
    57121 gggattggga tggtccatca gcactttatg cttgttgatg cctttactgt aacagaaaac
    57181 atcgtgttgg gaagcgagcc tagtcgcgca gggatgcttg accataaaaa agcacgaaaa
    57241 gagatccaaa aagtttctga acagtatgga ttgtcagtca acccagatgc ttacgttcgt
    57301 gatatttcag ttggaatgga acaacgggta gaaattttaa aaacacttta ccgaggagca
    57361 gatgtactga tttttgatga gccgacagct gtattgaccc ctcaagaaat tgatgaatta
    57421 atcgtgatca tgaaggaatt agtcaaagaa ggcaagtcga tcattttgat tacgcataag
    57481 ttagatgaaa tcaaagcagt agctgaccgc tgtacagtta tccgccgtgg aaaaggaatc
    57541 ggtacagtca acgttaaaga cgtaacctca caacaattag ccgatatgat ggttggaaga
    57601 acggtttcat tcaaaacgat gaaaaaagaa gcgaagcctc aagaagtcgt tttgtctatt
    57661 gaaaatctag tggtgaaaga aaatcgtgga ttagaagccg tgaaaaactt gaacttagag
    57721 gttcgtgctg gcgaagtact tggtatcgct ggaatcgatg gaaacgggca gtcggagttg
    57781 atccaagctt tgactggttt gcgaaaggca gaaagcggac atatcaagct aaaaggggaa
    57841 gacatcacta ataaaaaacc ccgaaaaatc actgaacatg gtgtaggaca cgtgccagaa
    57901 gaccgtcata aatacgggtt agtcctagat atgacattat ctgaaaatat cgcactacaa
    57961 acctatcatc aaaaacctta cagtaaaaac ggcatgctga attattcagt aatgaatgaa
    58021 catgccagag aattgatcga agaatatgat gttcgaacaa cgaatgaact tgttcccgca
    58081 aaagctttat caggcggaaa tcagcaaaaa gcaattatcg ctcgtgaagt cgaccgagat
    58141 cctgatctgt tgattgttgc aaatccaact cgtggactgg atgtaggtgc gatcgaattt
    58201 attcataaac gtctgatcga acaaagggac aaatacaaag cagtgttact gatcagtttc
    58261 gaattagaag aaattttaaa tgtttcggat cgtattgctg ttatccatga aggagaaatt
    58321 gtcggtatcg ttgatccgaa agaaacatct gaaaatgaat taggtctatt gatggcgggc
    58381 tataccttag aagaagcacg aaaagagtta gaaaaggggg ctggcgcaca tgaatgatcg
    58441 cagcgaaaaa ttccgtaatt tattagtgcc tgtactttca gttgttttag gattgatctt
    58501 aggcgcgata ttgatggctg cttttggttt tcagcccatc caaggttatt cttctatgct
    58561 agatgcagcc cttggttcgc aaagagggat aggtgaaacg ttaaggcaag caacgccgtt
    58621 gatttttaca gcattaggtt tttctgtagc taactcagct gggtttttca atattgggct
    58681 ttctggacaa gcactttgcg ggtggatcgt cagtgtctgg gtggcacttg cgtttccaga
    58741 tctgccaaaa gttgttttgc ttccgttatg cgtgatctta ggtgccttag ctggtgcgat
    58801 ggcagcggct gttccaggtt tacttcgagc attttttgga acaagtgaag tgatcgtaac
    58861 aatcatgatg aactatatct tattatacgt aagcacattt gctttacatg aagtgatgcc
    58921 tgaaagctat cgctcaagtt tggactcttc caatatgatc agtcaaaatg cctcactgcg
    58981 gttaccatgg ttaacacaag cttttggcgg ctctcgcgta aactcaggat tatttttagc
    59041 aatcatcgcg cttattttcg tttggctgct gatgaagaaa acgactttag gatttgaaat
    59101 ccgttctgtt ggattgaatc cttttgcttc tgagtatgca ggaatgagta gtaaacgtac
    59161 gatcgttttg tcgatggtca tttctggcgc tttggcaggg cttggcggtg tggttgaagg
    59221 attaggaacg tatcaaaact tctttgttca aacgacttcg ctatctattg gatttgacgg
    59281 aatggctgtt tccttgcttg gttctggatc agcaatcggt attcttttat cagcgatctt
    59341 gttcagtatt ttgaagatcg gtggacttgg catgcagaca ggagcaggtg ttccgtttga
    59401 gatcgtcaat gtatcgattg ctttgattat cttctttgtc gggatcaact tcctgattcg
    59461 tttcgtcatg gctaaagtct tccaagggaa aaaacaagaa gagatcgttg cgacaataga
    59521 atcgaaacca acgaatcaaa accatgaagg gggcgaacta taatgtcgac tatcgaatta
    59581 attgccttga tccttacttc tacactggtt tattcaacac cgctaattct aacgtcacta
    59641 ggcggaactt tttctgaacg aagcgggatc gtaaacgtag ggctagaggg aatcatggtc
    59701 atgggtgctt ttagttccat cgttttcaac ttgacgatga gtccatcact tggttctatg
    59761 acaccatgga tcgctatttt agtgggtggc gtcgtaggta tcctattttc tctgattcac
    59821 gcagtagcaa cagtcagttt gcgtgctgac catattatca gcgggacagt aattaatctg
    59881 atggcacctg ctttaggtgt tttcttgatc aaagcatggt atggtaaagg tcaaactgat
    59941 aacatcacgc agaatctggg gtatttttct ttcccaggat tagcagatat tccggtcatt
    60001 ggaccaattt tctttaaaaa tacattctta cctgcttatt gtgctatttt gattgctgtc
    60061 ctagcttggg tgatcatctt caagacgaaa ttcggcttgc gcctccgttc agttggtgaa
    60121 aatcctcaag ctgccgacac attaggtatc aatgtatatg ctatgcgtta ttcaggcgta
    60181 ctgatttctg gcttgttagg cggtatgggc ggtgctgttt ttgctcagtc gatttccggt
    60241 aacttttcag ctggtacgat cgttggacaa gggttcatct ccatggctgc tatgatcttt
    60301 ggtaagtgga atcctttagg ggcaatgggt gcctcattgt tctttggttt tgctcaaagc
    60361 ttgagtatca ttggcgcaca attaccagtt atttcttcga ttccgccagt attgctgcaa
    60421 attgctccat atttgctgac aatcattgtg ctggttgttt tcttagggaa agcttctggt
    60481 ccaaaagcaa acgggaagaa ctatatcaaa tcaaaataat cttttagcga ataaaaaggg
    60541 tgggttacgg gaagtgtttt tcgtctcgcc ctttttgttt taaaggcaat aaaaataaaa
    60601 agaaagaagg aataatcatg tttaaacgcg tacatctgat cgtcatggat tcagtaggaa
    60661 ttggagaagc accagatgcc gataagttcg gtgatgttgg ttctgataca ttaggacaca
    60721 ttgcgaaaga agcaggattg aacgttccac atttagagca gcttggttta ggaacgatcc
    60781 gtcctcttga aggtgtggaa tcagtgaaag atcatcaagg ctatgcgacg aaattagaag
    60841 aagtttctgt agggaaagat acgatgacag gccactggga aatcatggga ttgaatatca
    60901 aaactccatt tcgtgtgttt cctaatggat tccctgatga tctgatcaaa caaatcgaag
    60961 aattttctgg ccgtaaagtc gtatgtaaca aaccttatag cggaacagct gttattgacg
    61021 attacggtga acaccaaatg aaaacaggcg atttaattgt atatacttct gccgatcctg
    61081 tccttcagat cgcggcacat gaagaaatca ttcctttaga agaattatat cggatttgcc
    61141 aattcgttcg tgatataaca aaagatgatc cgtatatgat tggccgaatc attgcacgtc
    61201 cgtacgtggg tgaaccagga gacttcacac gaacaagcaa tcgccatgat tatgcgttga
    61261 atccattcgg acacacagtc cttgattctt tgaaagaagc aggaaaggac gtgattgctg
    61321 ttggaaagat caacgatatt ttcaacggac aaggaatcac tgaatctgtc cgcacgaaaa
    61381 gcaatatgga tggcgttgac cagctgctga aagttatgaa aaacgatttt tcaggaatca
    61441 gctttaccaa tttagtagat tttgatgcat tatacggtca tcgtcgggat gtagtcggct
    61501 atgcgcatgc gattgaagaa tttgacttac gaattccaga attgcttgaa gcgatggaag
    61561 aagacgactt gctaatgatt acagccgatc acggaaacga tccgacgttt actggtaccg
    61621 atcatacgcg agaatatgta ccgttattgg tttacagtaa aaaaatgaaa gaacaagggg
    61681 cattgcctca aggatattat tcagatattt cagcaacgat tgctgagaac tttagtgttt
    61741 cttcgactga aaatggcgaa agcttcttga aattattaaa ataatctttt taaataggag
    61801 aaagcaaatg accaagttaa gcgagatgtt acaagaaacg acccagttta tccttgataa
    61861 aggagtaaaa gaaattgatt ttggtttgat tctaggttca ggattaggtg aattagcaga
    61921 tgaaatcgaa gatgctgtaa tgatttctta tgatgagatc ccgttctttc ctgtttcgac
    61981 agtagttggg catgcaggaa agctagttta tgggtctctg gcaggcaaga aagtgttagc
    62041 catgcaaggg agattccact actatgaagg tcattccatg caaacagtga cctatccagt
    62101 acgtgtgatg gccggactag gggcccattc agtcattgtg actaatgcat gtggtggtgt
    62161 caacgaatca tttgtaccag gagatttgat gctgattacc gatcatatca attttactgg
    62221 tgaaaatcct ttgatcggtc cgaatgaaga tgcaatgggc cctagatttc cagatatgag
    62281 tcaagcttat acgcctgact atcaagcaac agcaaaagca gcagcagaaa aactaggttt
    62341 ggatcttaaa gaaggcgtat atatgggcta ttctggacca acttatgaaa cgcctgcgga
    62401 gatccgaatg tctcggacaa taggagccga tgcagtaggg atgtcgactg ttccagaagt
    62461 catcgtagca gctcacagcg gattaaaagt gttaggaatc tcttgtatta ccaacttagc
    62521 agcaggtatg caagcgaatc tgagccatga agaagttgta gaaacaactc agagagtcaa
    62581 acaatctttt aaagcattgg ttaaagaaac attgacatta ttgtaatagg aggaacaata
    62641 aaatgagtgt gcatattgaa gcgaaagaag gcgagatcgc cgataagatt ttacttccgg
    62701 gagatccttt gcgagctaaa tatattgcgg agactttttt ggaagatcca gtttgttaca
    62761 atcaggtacg cggtatgtta ggctttaccg gcaaatataa aggagaacgt atttctgttc
    62821 aaggaacagg aatgggaatg ccatcagcca ccatctatgc ccatgaattg atccagtcgt
    62881 atggtgtaaa gaaattgatt cgagtaggta catgcggtgc attgtcaaaa gacgtccatg
    62941 ttcgtgattt agtactagca caaggtgcag cgaccagttc ttcgatgatc gaaaaaaatt
    63001 tccaagcctt tcattttcct ccaatcagtg atttcaatct attactgaaa gcatatgaga
    63061 tagctaaaga aaagggctat acggttcatg taggaaatgt tctttcggaa gattctttct
    63121 acaaagatga tttgacagag acgttccaat tagctgaact tggcgtttta ggagtggaaa
    63181 tggaagcagc ggctctttat tacttaggcg cgaaatacca tgtgcagaca ttaagtttga
    63241 tgaccgttag cgaccatttg atcaccggtg aagaaacaac agctgcagaa cgtcaatcta
    63301 cgttcaatga aatgatcgaa gtaggattgg aaacagcgat agcagaataa gaaggaaatg
    63361 aaaaagctgc cctgcattaa gtaataagaa catccaagca aaaatagctc ctcatgtttt
    63421 tgacttggct ggacttatta ttgcaaatgt aagcttttga acaccgttta ccaagaggtt
    63481 gtgaatctgc cgtttaactc tgagtcacaa ggaacaattt caaaaaacag cttttcatgt
    63541 ttgatgaata ttgtgacttg tgaccgagaa gttggcagga gaaaaccgtt tatacgaaaa
    63601 aagggactgt gacaaatcgt gtcacagtcc cttttttata gtgtttttta taggtagtat
    63661 tttttagcaa ctgttaagtc atcatttaat tcataaacaa gtggttgacc tgttggaatt
    63721 tcaagatcca tgatgtcttc gtcagagata ccttcgatat gtttagctag ggcgcgtaat
    63781 gagttaccat gtgcagctac taaaacagtt ttgttgtcta gtaatgctgg agcaatttca
    63841 tcttgccaga atggcaaagc gcgttctaat gtcactttca agttttctcc accaggaata
    63901 tcgcgtttgt ctaacattgc gtaacgacgg tcatttgctg cagaaccttc gtcagtttct
    63961 tccattaatg gaggaagagt atcgtaagaa cgacgccaga tgtgcacttg ttcgtcgccg
    64021 tatttttcag ctgtttcttt tttgttcaaa ccttgtaatt taccatagtg acgttcgttt
    64081 aagcgccatg atttgatttg tggtacccaa agttgatctg aatattctaa gatcaagtta
    64141 catgttttga ttgcacgagt taaaacagaa gtgtaagcaa catcaaattc gattccagct
    64201 tctttgattt tgcgtccgcc ttcttttgct tcttcgattc cttctggtgc tagatttaca
    64261 tcagcccaac cagtaaattg gttcaatgca ttccattcac taagaccgtg acgagaaaaa
    64321 actaattttg gcatgtttag ctctcctttt aagataggtt tatatttctg aaattttcag
    64381 ttctgtttta ttgtacaatt ttttggaaga gatttccatc gaaaaattag ataagattct
    64441 atgagaaaac aagtagagaa tataaaaaaa cgaacagtgc ccacgcaact gttcgttttt
    64501 aggtattaga tgcataattg ctcgatttct ttttcaggta aattgatata tttataacat
    64561 gttccaactg aaacaccgca ttttgaagaa ataaattgga tcgtttcttt tttttcataa
    64621 tagagacgtc ggattttttt gatcgttttt gcatcgattt ttggtcttcc gccgattttt
    64681 ccttttttac gagcttcatc taatccaact aatgtacgtt ctttgatcaa tgcgcactcc
    64741 atgtttgcta ggttttccat taattggaaa tagatttttc ccatttcgcg cgtatcgatt
    64801 ccttcatcaa gactaatcaa gtgcagcccg cgatctttga ataattgcgt gagttctgtt
    64861 aattgccgcg tagatttgcc taatcgatga agttggcaaa tgactagtgc atcgccttgt
    64921 tgcatgtcag cgatcactga ctccaaatga acagcagtag aatcattttg ttccacttca
    64981 tatgtctcat ggaaaatttc ttgacaacca aagtcagata attgatcaac ctgagttgtt
    65041 aaatcaacgt catttatggt tgtgcgtgca taaccaataa ttttcatggt gattcctttc
    65101 tagcagtgat tttctaactg gatataacag taaaaatgta gcataaagta cgtcaaaaag
    65161 atagtttttt cgcaaatttt ccgctgtctt tttttattgg atgatcaagc agtttttctt
    65221 tatttacgac ggattgcgtc aagaatctca acgccttttt ctgagccgac aactacttta
    65281 gaaaccatgt ttaggaaaag cccatgttct actaccccaa caagttcatc taaataggta
    65341 gctaagcttt ctggctgttc gatgacttct agatgcagat caatgatgta atgaccacca
    65401 tctgtggtta agacttctcc gttttcgtct gtacgcaaga cgggttggaa tcttttttct
    65461 tcaaaaatat gaagtagctg ttgggagcca taagggatca cttcaactgg gagtgggaac
    65521 ttcccaagtt tatcgactaa tttagaagaa tcaacgatcc aaatcgtttc ttttgagtac
    65581 gtagcgacta ttttctcgaa aagcaaagca gcgccgccgc ctttgatccc ttgaaaatca
    65641 gcactgattt catcagcacc gtctattgtc aaatcgacta cggggacttc atcaatactc
    65701 tttaacggta ttcctaattt ttccgcttgt tcttttgtcg catttgaagt agtaactcct
    65761 gtgatacgta aaccttcttc acgcatacgg cgaccaatct cttctaccat ataataggcg
    65821 gttgaaccgg tcccgagacc tacgatcatc ccgtccttta cgaatttcgc ggcttcaatg
    65881 ccagctaatt gttttaaatt catctttgcg tccacctttt tttagtttga gcatcgtgct
    65941 ttcctcacta ttttagcgtg atttacggta aaaagatacc attctttttt attccaataa
    66001 agctttttca aaaaaaattg catctcttgt tgacatgttt tttcattcgt gatattctaa
    66061 caaaggtgct ttatctacag gtttctgtga agaaacgtgc tgactgttta tcaaagcata
    66121 tttgataagg atgcagacat tgcatttatt ttttatcaca aaaaaagaac cacctggatg
    66181 tgtggaacta gacgcaaatc gtgggaagga ggaaacaagg aatgcctaca attaaccaat
    66241 tagtacgtaa acctcgtaaa tcaaaggtgg aaaaatctaa ttcacctgct ttgaacaaag
    66301 gatataacag ctttaagaaa actcaaacta acgtaaactc acctcaaaaa cgtggggtag
    66361 caactcgtgt gggtacaatg acacctaaaa aaccgaactc agctttacgt aaatatgcac
    66421 gtgttcgttt gtcaaactta attgaagtta ctgcttatat cccagggatt ggtcataact
    66481 tacaagaaca cagtgttgta ttattacgcg gtggtcgtgt aaaagactta ccaggggtac
    66541 gttaccatat cgttcgcggt gctttagata ctgctggtgt taacgaccgt aaacaaagcc
    66601 gttctaaata cggaactaaa aaacctaaag cttaatttta attattaaac aaatgaaact
    66661 tgcttctact atatagaagt aattactatg aacaatattt cggaaggagg agttacggat
    66721 gccacgtaaa ggtcctgttg caaaacgtga tgttttacca gatcctattt ataactcaaa
    66781 attagtaact cgcttgatca accgtgtaat ggttgacgga aaacgcggga ttgcagctaa
    66841 cattatctat aatgcctttg acttgatcaa agaatctaca ggtaacgatc cattagaagt
    66901 gtttgaacaa gcaatgaaaa acgttcaacc tgttcttgaa gttaaagcac gtcgtgttgg
    66961 gggttcaaac taccaagtac cagttgaagt tcgccctgaa cgccgcgtta ctctaggtct
    67021 tcgttgggta gtaaactacg ctcgcttgcg cggtgaacac acaatggaag aacgcttagc
    67081 aaaagaaatc atggatgctg caaacaacac aggtgcttct gttaaaaaac gtgaagacac
    67141 tcataaaatg gctgatgcca accgtgcgtt tgctcactat cgctggtaag attctctctg
    67201 tttggtcggc ttttataagt cgacctcaga tagtgtcctt atttttagca actagatagt
    67261 aaagagagga gaaacaagga gaatgaccag agaattttct ttacaaaaca ctcgtaatat
    67321 cggtatcatg gcccacatcg atgctggtaa aacgactgct actgaacgta tcttgtacta
    67381 tactggtaaa atccataaaa ttggtgaaac tcatgaagga gcttcacaaa tggactggat
    67441 ggaacaagaa caagaacgtg gtattacgat cacttctgct gctactacag cacaatggaa
    67501 gggtcaccga atcaacatca tcgacacacc aggacacgta gacttcacag ttgaagttga
    67561 acgttcattg cgtgtacttg atggtgctgt aactgttctt gatgcacaat caggtgttga
    67621 acctcaaact gaaacagttt ggcgtcaagc aacaacttat ggtgtacctc gtatcgtatt
    67681 tgcaaacaaa atggacaaga tcggtgctga cttcttatat tcagtatcaa ctttacatga
    67741 ccgtttgcaa gcaaacgctc acccaatcca attaccaatt ggtgcggaag acgacttcac
    67801 aggaattatc gaccttgtaa caatgaaggc tgaaatgtat acaaacgatc ttggaacaga
    67861 gatcgaagaa acagaaattc ctgaagaata ccgcgaatta gctgaagaat ggcgcgaaaa
    67921 attggttgaa gctgtagctg aaactgatga agaacttact ttgaaatact tagaaggtga
    67981 agaaatcact gaagctgagt taaaagaagg tatccgccgc gcaacagtta acgtagaatt
    68041 ctacccagta ctatgtggtt cagcatttaa gaacaaaggg gttcaattac tattggacgc
    68101 tgttcttgat tacttgccat caccgttaga tatcccagct atcaaaggga ttgaccctaa
    68161 aactgatgaa gaagtagaac gtcctgcaga cgacagcgct cctttctcag ctttagcatt
    68221 taaagttatg actgacccat tcgtaggtcg tttaactttc ttccgtgtgt actctggtgt
    68281 tttacaatca ggttcatacg tacaaaacgc aacaaaaggc aaacgtgaac gtgttggtcg
    68341 tatcctacag atgcatgcca actctcgttc agaaatctct gaagtttacg ctggagatat
    68401 cgctgctgct gttggtttga aagacacaac tactggggac acactatgtg atgaaaagag
    68461 tctagttatt cttgaatcca tggaattccc agaaccagtt atccaagtcg ctattgaacc
    68521 taaatcaaaa gctgaccaag ataaaatggg tgtggcttta caaaaactat ctgaagaaga
    68581 tcctactttc cgtgctgaaa caaacgtgga aacaggcgaa acaatcatcg ctggtatggg
    68641 tgaacttcac ttagatatca tcgttgaccg tatgcgtcgt gaattcaaag ttgaagctaa
    68701 cgtaggtgcg cctcaagtat cttaccgtga aactttccgt gctggcactc aagccgaagg
    68761 taagtttgta cgtcagtctg gtggtaaagg tcaatacggt cacgtatgga ttgaatttac
    68821 accaaatgaa gaaggtgctg gtttcgaatt tgaaaatgcg atcgtcggtg gggttgttcc
    68881 tcgtgaatac attccagctg ttgaaactgg tttgaaagat gctatggaaa atggtgtctt
    68941 agctggctat ccattagtag atatcaaagc taaactttac gatggttcat accatgatgt
    69001 cgattcaaat gaaactgcct tccgtgttgc tgcttctatg gcattacgtg cagcagctaa
    69061 gaaagctaat ccagtaatcc ttgaaccaat catggctgta gaagttgtta tccctgaaga
    69121 ttatttaggt gatgttatgg gtcacgtaac tgctcgtcgt ggacgtgttg aaggtatgga
    69181 agctcgcgct ggcggccaac aagttgttcg tgcgatggtt ccacttgctg aaatgtttgg
    69241 ttatgctaca actcttcgtt ctgctactca aggtcgtggt acatttacaa tgacatttga
    69301 ccactacgaa gatgtaccaa aatcagtaca agaagaaatc attaagaaaa acggcggaaa
    69361 agctgaataa tttcttaaaa ccggatagtc ctgcaaagag attatccaaa gagactatat
    69421 ttttaatata gtttcgtgta aaataattat cgatgatatg ggcatgtggt gtaccttgtg
    69481 tacatcatat acctatcaga caaataaaaa atatattgta tttttaggag gacattttaa
    69541 aatggcaaaa gaaaaatttg accgttctaa accacacgtt aacattggta ctatcggaca
    69601 cgttgaccat ggtaaaacta cattaacagc tgcaatcaca actgtactat ctaagaaaaa
    69661 cggcggccaa gctatggctt acgatcaaat cgatggtgct ccagaagaac gcgaacgcgg
    69721 aatcacaatc tcaacagctc acgttgagta tgaaacagat acacgccact acgctcacgt
    69781 tgactgccca ggacacgcgg attacgttaa aaacatgatc actggtgctg ctcaaatgga
    69841 cggagctatc ttggtagttt ctgctgctga cggcccaatg cctcaaactc gtgaacacat
    69901 cctattgtct cgtcaagttg gtgttcctta catcgttgta ttcttgaaca aagtagacat
    69961 ggttgatgac gaagaattac tagaattagt tgaaatggaa gttcgtgacc tattaacaga
    70021 atacgaattc cctggtgacg atgttcctgt agttgctgga tcagctttga aagctctaga
    70081 aggcgacgct tcatacgaag aaaaaattct tgaattaatg gctgcagttg acgaatacat
    70141 cccaactcca gaacgtgaca acgacaaacc attcatgatg ccagttgaag acgtgttctc
    70201 aattactgga cgtggtactg ttgctacagg tcgtgttgaa cgtggacaag ttcgcgttgg
    70261 tgacgaagtt gaagttgttg gtattgctga agaaacttca aaaacaacag ttactggtgt
    70321 tgaaatgttc cgtaaattgt tagactacgc tgaagctgga gacaacattg gtgctttact
    70381 acgtggtgtt gcacgtgaag acatccaacg tggacaagtt ttagctaaac caggtacaat
    70441 cacacctcat acaaaattct ctgcagaagt atacgtgttg acaaaagaag aaggtggacg
    70501 tcatactcca ttcttcacta actaccgtcc acaattctac ttccgtacaa ctgacgtaac
    70561 aggtgttgtt gaattaccag aaggaactga aatggttatg cctggcgaca acgtaacaat
    70621 ggaagttgaa ttaatccacc caatcgctat cgaaaacggt actaaattct caatccgtga
    70681 aggcggacgt acagttggtg ccggtgtcgt tacagaaatc aaagcttaat tcacttaagt
    70741 tttaaagtaa agcaacattt attcggacgt aatcgctcgg aacgaaggtc ttaggatctt
    70801 tgttccgagc ttttttattt attgcaggat caggaaaaaa gacaggagta ttataaatag
    70861 aagaaacacg aaataaaaga gtcagtattt tctaaatgaa actttatgaa aacaaaatgt
    70921 tttttacaag aaaaagcctt gctttgtgag tttatatata ttataatgac aaaggtgcgt
    70981 ttactttagt gaattgcaca gacgtaatca gaatgatttc gtcggctaag aaacgagagg
    71041 ttgcgacacg cccggacgct ttgccacgaa cgagcgtgac ggaaattttc gtggagctat
    71101 gtctactttt caaaataggc gaaggaggga acaagatggc aaaacaaaaa attcgtatcc
    71161 gtttaaaagc gtatgaacac cgtattttag atcaatcagc ggataaaatc gtggaaactg
    71221 caaaaagaac tggagctagc gtgtctggtc caattccatt accaactgaa cgcagtcttt
    71281 acacaatcat ccgtgcgact cataaataca aagattcacg cgaacaattc gaaatgcgta
    71341 cacacaaacg tcttatcgac attgtgaacc caacaccaaa aactgttgat gctttgatga
    71401 agctagactt accatctggt gtaaacatcg aaatcaaatt ataaaactaa aacaaaaata
    71461 atggaggtgt actcatgacc aaaggaatct tagggaaaaa agtgggaatg acacaaatct
    71521 tcactgaatc tggtgaatta attccagtaa ctgttgtaga agctactcca aacgtagtac
    71581 tacaagtgaa aacaatggaa acggatggct acgaagctat tcaagttggt taccaagata
    71641 tgcgtgaagt tttatcaaac aaacctgcga aaggtcatgt tgcaaaagca aacacggctc
    71701 ctaagcgctt cattcgtgaa ttcaaaaatg ttgagctagg agaatatgaa gtaggaaaag
    71761 aaattacagt agatgttttc caagcaggag acattattga tgtaacaggt actacgaaag
    71821 gtaaaggatt ccaaggggtt atcaaacgcc acggacaaag ccgcggacca atggctcacg
    71881 gttctcgtta ccatcgtcgt cctgggtcaa tgggtccagt tgcacctaac cgtgtattta
    71941 aaaacaaacg tcttgctggc cgtatgggtg gcaaccgcgt aactatccaa aacttggaag
    72001 ttgtacgtgt cgatgcagaa agaaatgtta tcttgatcaa aggtaatgtt cctggagcta
    72061 aaaaatcttt aattactatc aaatcagctg tgaaagctaa ataattgtag gaagaaagga
    72121 ggaactaagg aatgccgaat gtagcattat tcaaacaaga tggaagccaa aacggtgaaa
    72181 tcacacttaa cgaagaaatc ttcggaattg aacctaatga aagtgttgtt tacgatgcaa
    72241 tcgtaatgca acgtgcgtca ttaagacaag gaacacacgc ggttaaaaac cgtagcgctg
    72301 ttcgcggcgg cggacgtaaa ccatggcgtc aaaaaggaac aggtcgtgca cgtcaaggat
    72361 ctatccgctc accacaatgg cgtggaggtg gcgtagtctt tggaccaaca ccacgttctt
    72421 acagctacaa acttcctaaa aaagttcgtc gtttagcaat gaaatctgta ttgtcagaaa
    72481 aagttgctga aaacaacttg gtagcaatcg aaggcttgaa cttcgacgca ccaaaaacaa
    72541 aagaattcaa acaagttctt gctaacttat ctatcgactc taaagtattg gttgttctag
    72601 aaaaaggtaa cgactttgct gctttatcag cacgtaactt accaaacgtt tctgtagtaa
    72661 cttctgataa tgtgagtgtg ctagacgttg tatcaaatac aaaagtgtta gcaacacaaa
    72721 ctgctcttac tcaaattgag gaggtgcttg cataatgaac ttactagacg taatcaaacg
    72781 cccagtgatc actgaaaaat caatgcttgc catggatgac aagaaataca cttttgaagt
    72841 ggacactcgc gcaaacaaaa ctttagtaaa acaagcggta gaagctgctt ttgacgttaa
    72901 agtcaaaaac gtgaacatcg tgaacgtacg tgcgaaattc aaacgtatgg gcaaatatgc
    72961 aggatataca aaaaaacgtc gcaaagcgat cgttacattg actgaagatt caaaagaaat
    73021 ccaattattc gaagctgctg aataagcact aatagataac tcattaaatt aggagggaaa
    73081 aacgtggcga ttaaaaagta caaacctacc tcaaatggtc gtcgtaacat gacaggttct
    73141 gattttgctg aaatcacaac atcaacacct gaaaaatcat tgttacaacc attgaaaaac
    73201 catgctggac gtaacaacaa cggccgcatc actgtacgtc atcaaggtgg cggacacaaa
    73261 cgccaatatc gcgtgatcga cttcaaacgt aacaaagata acgttgttgc aactgttcaa
    73321 acgatcgaat atgatccaaa ccgttcagct aacatcgcgt tagtacacta tgaagatgga
    73381 gtgaaagctt acatcttagc acctaaagga ctagaagtgg gtatgaaact tgtttcaggt
    73441 ccagaagcag atatcaaagt cggaaatgct cttccattag aaaacattcc agttggtact
    73501 gttatccaca acattgaaat gaaacctggt aaaggtggac aattgatccg ttctgctggt
    73561 acaagtgctc aagtacttgg taaagaaggc aaatacgtat tgatccgctt gaactctggt
    73621 gaagttcgta tgatcttagc tgcatgccgt gctacaatcg gttctgtagg taacgaacaa
    73681 cacgaattaa tcaacatcgg taaagctgga cgctctcgtt ggatgcgtaa acgcccaact
    73741 gtacgtggta gcgtaatgaa ccctaatgat cacccacacg gtggtggtga aggtaaagct
    73801 cctatcggac gtaaagcacc agtttctcct tggggtcaac cagctcttgg ttacaaaact
    73861 cgtaacaaaa aagctaaatc agacaaactt attgttcgtc gtcgcaaaaa taaataatta
    73921 ctttgaccat gtgtcgcaca ttttgagagg aggttcacca tgggtcgtag tttaaagaaa
    73981 ggaccttttg tcgatgagca tttaatgaaa aaagttgaag ctcaagcagg ggttgaaaag
    74041 aaaaaagtta tcaaaacttg gtcacgccgt tcaacagttt tcccaagttt tgttggatat
    74101 accatcgcag tttatgatgg acgtaaacat gtaccagttt acatccaaga agacatggta
    74161 ggacacaaat taggtgaatt tgcacctaca agaacttatc gtggacatgc tgctgacgat
    74221 aagaaaacga aacgctaatt tgaggggagg ataaatccaa atggcagaac aaatcacatc
    74281 agctaaagca actgcaaaaa cagttcgcac ttcacctcga aaagcccgtt tagtaattga
    74341 ccttatcaga ggtaaaagtg tcgcagatgc aatttcaatc ttgaaattca caccaaacaa
    74401 atctgctgga atcattgaaa aagtattgat gtcagcagtt gcgaatgcag aaaataactt
    74461 tgacttagat gttgaaaact tggtagtaag cgaagctttt gttaacgaag gacctacaat
    74521 gaaacgtttc cgtcctcgtg caaaaggatc agcttctcca atcaacaaac gtacaagtca
    74581 tatcacggta gtcgtatcag aaaaataagg agggataatc agtgggtcaa aaagtacatc
    74641 caattggaat gcgtgtaggc atcatccgcg actgggatgc taaatggtat gctgaaaaag
    74701 agtatgctga gttcttacac gaagatttaa gaatccgtaa atttatttca actaaacttg
    74761 ctgatgctgc tgtatcaaca gttgaaatcg aacgcgcaac aggtcgcgta aacatttcaa
    74821 ttcacacagc taaaccaggt atggttattg gtaaaggcgg ttctgaagtc gaaagcctaa
    74881 gaaaagaatt aaacaaatta actggtaaaa gaatccatat caatatcgtg gaaatcaaaa
    74941 aaccagatct agatgcaaaa ttagtaggtg aaggaatcgc acgtcaatta gaaaaccgtg
    75001 ttgctttccg tcgcgctcaa aaacaagcca tccaacgctc aatgcgtgct ggcgctcaag
    75061 ggatcaaaac tcaagtatct ggtcgtctaa acggagcaga tatcgctcgt tcagaaggat
    75121 actcagaagg aactgttcct cttcatactt tacgtgcgga cattgattac gcatgggaag
    75181 aagcagatac aacatacgga aaactaggag ttaaagtgtg gatctatcgt ggagaaattc
    75241 ttccaactaa aaaaaacact gagaaaggag ggaaataatc atgttagtac ctaaacgtgt
    75301 aaaacaccgt cgtgaattcc gcggaaaaat gcgcggggaa gctaaaggcg gaaaagaagt
    75361 agcattcggt gaatacggtt tgcaagctgt tgattcacat tggatcacaa accgccaaat
    75421 cgaagctgct cgtatcgcaa tgactcgtta catgaaacgt ggtgggaaag tatggattaa
    75481 aattttccct cacaaatctt atactgccaa agcaattggg gtacgtatgg gttctggtaa
    75541 aggggcacct gaaggatggg ttgcaccagt aaaacgtggt aaaatcatgt ttgaaatcgc
    75601 aggcgttcct gaagaagtag ctcgtgaagc gttacgtcta gcttctcaca aattaccaat
    75661 gaaaactaag atcgtaaaac gtgaggaaat gggtggtgaa tcgaatgaag gttaaagaaa
    75721 tcagagaatt aaccactgcc gaaatgcttg atcaagaaaa acaattaaaa gaagaattgt
    75781 ttaatcttag attccaatta gcaacaggtc aattagaaaa cactgcacgt attaaagaag
    75841 tacgtaaatc gattgcacgc atcaaaactg tgttgcgtga acaagctaag taattatgga
    75901 aggaggccat taagcgtatg actgaaggaa gaaatcaacg caaagtttat caaggtcgcg
    75961 tggtttcaga caaaatggat aaaacaatta ccgttgctgt cgaaacaaag aaaaaccacc
    76021 ctatctatgg caaacgcatg aactattcta agaaatacaa agtgcatgat gaaaacaaca
    76081 cagcaaaagt tggcgacatc gtgagaatta tggaaactcg tccattatca gctacaaaac
    76141 gtttccgttt gttggaagta gtcgaagaag cagttattat ctaataacac gagattttcc
    76201 tatatagatt gaatgcaaaa tctgaaagga ggatacacaa cgtgatccaa gcagaaagtc
    76261 gtttaaaagt cgctgataac tcaggcgcac gtgaaatttt gacgatcaaa gtccttggtg
    76321 gatctggtcg taaaactgct aacatcggtg atgtgatcgt tgctacggtt aaacaagcaa
    76381 cgccaggtgg ggttgtcaaa aaaggtgacg tcgttaaagc cgttatcgtt cgaacaaaat
    76441 caggagctcg tcgtacagac ggttcatata ttaaatttga tgaaaatgct gcagtgatta
    76501 ttcgtgatga taaaagccct cgtggaacac gtatctttgg gccagttgca cgtgaactac
    76561 gtgaaaacaa cttcatgaag atcgtttcac tagcaccaga agttttataa tcttgagaca
    76621 cttatcaaag gaggtgcgaa acagttatgt ttgttaaaaa aggcgataaa gttaaagtta
    76681 tcactggaaa agacaaaaac aaagaaggcg ttgtactagc agcgttcccg aaaaaagata
    76741 aagttattgt cgaaggtgta aatgtcgtta aaaaacacca aaaaccttct caagctgctc
    76801 ctcaaggtgg aattgttgag atggaagcgc caattcatgt ttctaacgtg atggtggttg
    76861 actctactgg tgtagctggc cgagttggct acaaagaagt agacggcaaa aaagtccgtg
    76921 tttctaaaaa aaccggtgaa gttttagata aataaaagtt taaggaagga gggtcttact
    76981 gaatgaaccg cctaaaagaa aaatatctta aagaagtaac tccatcattg atggaaaaat
    77041 ttaactatag ctctgttatg caaacaccta aagttgaaaa aatcgtcatc aacatgggtg
    77101 ttggtgatgc ggtatcaaac gctaaaaact tagataaagc agttgaagaa ttaactttga
    77161 tcactggtca aaaaccaatg attacaaaag ctaaaaaatc aatcgctgga ttccgtttac
    77221 gtgaaggaat gccaattggt gcaaaagtta cattgcgcgg agaaagaatg tacgaattct
    77281 tagacaaatt ggtttctgtt tcactaccac gtgtacgtga cttccatggt gtaagtaaaa
    77341 aagcctttga cggtcgtgga aactatactt taggtattaa agaacaattg atcttcccag
    77401 aagtagatta tgatttagta gataaagtac gtggtatgga catcgttatt gtaacaacag
    77461 caaactctga tgaagaatct cgtgagttgt tgacacaatt aggcatgcca ttccaaaaat
    77521 aattaaagga ggcgaactac gtggctaaaa aatcaatgat tgctaaaaac aaacgtcctg
    77581 caaaattttc aacacaagct tatactcgtt gcgaacgttg cggacgtcca cattcagttt
    77641 atcgtaagtt ccatctttgc cgtatttgct tccgcgaact tgcctataaa ggtcaaattc
    77701 ccggcgtgaa gaaagctagc tggtaaaaag taaattcgca taagaaggag gtaaaagatc
    77761 aatggtcatg acagatccaa ttgcagattt tctaactcgt atccgtaacg caaacatggt
    77821 taaacatgag tctttagaag tacctgcatc aaaaattaaa cgtgacatcg ctgaaatctt
    77881 gaaacgtgaa ggtttcgttc gtgatgttga atacatcgaa gatgacaaac aaggcgtgat
    77941 ccgtgttttc ctaaaatttg gtaaaaacgg cgaacgtgtt atcacaaact taaaacgtat
    78001 ctctaaacca ggtttgcgtg cttatgtcaa agctgacgaa gtaccaaaag tattgaacgg
    78061 tttaggtatc gcaatcattt cgacttctga aggtgttgtc actgataaag aagctcgtga
    78121 aaaaaatatc ggcggcgaag ttatcgctta cgtatggtaa tcaagtagaa tctacaagga
    78181 ggtgtcttta agtgagccgt atcggaaata aagtcgttgt tatccctgaa ggagtaacag
    78241 ttactcaaga cggaaacaac gttacagtta aaggaccaaa aggtgaattg actcgtactt
    78301 tttcagcaga tatcaaaatg aatatcgaag gaaacgaagt aactttcact cgtccaaacg
    78361 acagtaaaga aatgaaaaca attcatggaa caactcgtgc gaacttcaac aacatggttg
    78421 taggtgtcag cgaaggtttc caaaaagcgt tagaactaat cggggttggg taccgtgcac
    78481 aattacaagg atcaaaactt gtattgaacg ttggttactc acatccagta gaaatcacac
    78541 caccagctgg agtaactgtt gaagtaccag ctaacacaca agtaattgtt aaaggtgcga
    78601 acaaagaaga agttggcgaa ttagctgcaa acattcgtgg aactcgtcct ccagaacctt
    78661 ataaaggtaa aggtattcgt tatgttggcg aatatgtacg ccgtaaagaa ggtaaaactg
    78721 gtaaataatc gtttagaaaa attgcataga agccagcagc aggaaaaagg catttggctg
    78781 aagtttacct tcaaaaaaat acatttttac ttgtgccgca gcttctattt ttcgaaacgt
    78841 atttactgct tgaaatagta gtacaataaa aataaagagg tgacaattgt gattacaaaa
    78901 ccagataaga acaaaacacg tcaaaagaga catcgtcgtg tacgtaacaa tatctctggt
    78961 actgctgagc gcccacgctt gaacgttttt cgttctaaca aaaacatcta cgctcaaatt
    79021 attgatgacg tagcgggtgt aacgctagca agtgcctcta ccttggataa agaaatttca
    79081 ggtggaacaa aaacagaagc agcacaagct gtcggtaaac tagttgctga acgtgcagct
    79141 gaaaaaggca ttaaagtagt agtctttgac cgtggtggat acctttacca tggccgtgtg
    79201 caagctttag ctgaagctgc tcgcgaaaat ggactagaat tttagaagaa ggaggaatac
    79261 cattcatggt ttatatcgat ccaaaacatt tggaattaga agaccgcgtt gttgcaatta
    79321 accgtgtaac aaaagttgtt aaaggtggac gtcgtctacg ttttgctgct ttagttgttg
    79381 tcggtgacaa aaacggacac gtagggtttg gtacaggtaa agctcaagaa gttcctgaag
    79441 caatccgtaa agcaattgaa gatgcgaaga aaaacttagt tgaagtacct atggttggtt
    79501 caacaatccc acacgaagta atcggtgctt ttagtggtgg tagaatccta atgaaacctg
    79561 ctgtagaagg ttctggggtt gctgctggtg gaccagttcg tgccgtatta gaattagctg
    79621 gggtagcaga tatcacttct aaatctttag gctcaaatac accaatcaac gttgttcgcg
    79681 caacagttga aggtttgaaa caattgaaac gtgcagaaga agttgcagaa cttcgcggca
    79741 aatcagttga agaattaatc ggataaggag gacaacaata atggctgaat taaaagttac
    79801 tttaaaacgc agtattatcg gacgtcctca aaaccaacgc gatacagtta aagcgttagg
    79861 tcttacaaag attaacagtt cagtggttaa gccttctaat gaagcaatta aaggcatgat
    79921 caatactgtt tctcacctag tggacgttga agaaatttaa tttagaaaaa tcataactag
    79981 aacattaagg aggtgccaaa cctatgaaac ttcatgaatt aaaacctgct gaaggttcac
    80041 gccaagtacg taaccgtgtt ggtcgtggta cttcatctgg taacggaaaa actgccggac
    80101 gcggacaaaa aggacaaaaa gctcgttcag gcggcggtgt gcgtttagga tttgaagggg
    80161 gacaaacacc attgttccgt cgtttaccaa aacgaggatt cacaaacgtg aaccgtaaag
    80221 actatgcagt cattaatctt gatgtattga accgctttga agacggagct gaagtaactc
    80281 ctgttgcttt agttgaagct ggaatcgtga aaaacgaaaa agctggaatc aaagtattag
    80341 ctaatgggga actaaacaag aaattaactg tgaaagcagc aaaattctct aaagcagctc
    80401 aagaagcaat tgaagcggct ggtggatcaa tcgaggtgat ctaatgttta gactattaaa
    80461 agatgctttt aaagtaaaag acattagatc gaaaatccta tttactgtat ttgtgttgtt
    80521 tgtatttcgc ctaggtgcac atattactgt accaggcgta aatgctgctt cattgcaaaa
    80581 cctttcttct ttgccatttt tcaacatgtt gaacttggta agtggtagtg cgatgcaaaa
    80641 cttttccatt ttctcaatgg gggtttcacc atacattact gcttctatcg tcattcagct
    80701 tcttcaaatg gacatcgtgc ctcgatttgt tgaatggtcg aaacaagggg aagttggtcg
    80761 taaaaaactg aatcaagcga ctcgatatct gacattagta ttggcattta tccaatctgt
    80821 cggtatcact gctggattca atcaatacgc tcaattaggt ttcgtgaata atcctaacgt
    80881 agcaacttac gtaacgatcg gtttgattct aacagccggt acgatgtttg ttacttggct
    80941 aggagaacag atcacagaaa aaggtatcgg aaatggcgta tcaatgatca tttttgcagg
    81001 tatcatttct agattgcctg aaagtatcag agaaatttat gaagattact ttataaatat
    81061 tgatccttca gacatatgga aatctgctat ttttgtggcc attttactag tagcggtctt
    81121 gttgatcgtg acattcgtaa catttttcca acaagctgaa cgcaagatcc cgatccaata
    81181 tacgaaacgc gtagctggcg cgcctacaag cagctatctg ccgttgaaag taaatgcagc
    81241 tggagttatt ccagttatct ttgctagttc gtttattgct acgccaaatg ctgttttaca
    81301 agcattgagc ggtagattcg gttctgaaaa ctggtacaaa gtgatgatgg agatctttaa
    81361 ctataataca gcacctggtg ctacgattta tacgattctg atcgttgcct tcactttctt
    81421 ctacgccttt gttcaagtaa accctgagaa attagcggaa aacttgcaaa agcaaggaag
    81481 ttatatacca agcgtacgcc ctggtaaggg gactgaagag tatgtctcaa gattactgat
    81541 gcgtttaagt acagttggtg cagtcttcct tggtttagtg gcattgcttc caatcattgc
    81601 tcaaatggtt tgggatcttc cacaatcaat cggattaggc ggtacaagct tactgatcgt
    81661 tatcggtgta gctttagaaa ctgcgaaaca gttagaaggc ttaatgctga aacgtaaata
    81721 tgttggattc attgagtaag aaagcgtgtt gaggtttccc ctcaacacac gttctcacac
    81781 atttattagg agggaaaaca atgaacctca ttttaatggg gctgccaggc gcaggtaaag
    81841 gaacacaagc tgaaaaaatc attgatgctt atggtattcc gcacatctca acaggagata
    81901 tgttccgcgc agcgatgcaa aacgaaacag ctcttggcct ggaagcaaag tcttatatgg
    81961 ataaaggtgc attagttcct gatgaagtaa caaatggaat cgtgaaagag cgactagctg
    82021 aaccagatac agagaaaggc ttcttattag atggctttcc acgtacgcta gatcaagcaa
    82081 aagctctgga cgcaatgcta aaagatttga ataaaaaaat tgatgctgtc atcgatatcc
    82141 atgttggtga agaaatcttg gtcgaacgtc tagccggccg atttatctgc agcaattgtg
    82201 gagcaactta ccataaaatt ttcaacccta caaaagttga agacacatgt gatcgttgcg
    82261 gtgggcatga attctatcaa agagaagatg ataaacctga gacggttaaa aatcgtctgg
    82321 ctatcaacat caaaaatagt gaaccaatct tggcttatta taaagaacaa ggtttgctaa
    82381 acactattga tggtgctcgt gaaatcgatg ctgtatttgc agatgtacaa aaaatcattg
    82441 aaaaatagca cgattgcccg tagccgactt gcattatgca gttactcttg tcaagttcaa
    82501 taaattatga tagaatatgt cagtccgact tctagagaat cctctagatg atccattttg
    82561 agaattttga ggtgggaact gcagtttccg ccattttatc gtgtgaaaat gcgaaacaag
    82621 tacaaggagg tactgtgcgt ggcaaaagaa gatatgattg aagtcgaagg tacagtcgtc
    82681 gaaactttgc cgaatgcaat gtttaaagtt gaactagaaa acggacacca agttcttgct
    82741 actgtttcag gtaaaattcg tatgcattac atccgtatct tacctggtga caaagtaacg
    82801 gttgaattgt ctccatacga tcttaaccgt ggccgtatta cttatcgctt taaataattg
    82861 tactccgtaa aactacagga ggtattatca tgaaagtaag accatcagta aaaccaatgt
    82921 gcgaacattg taaagtaatt cgtcgtaaag gacgcgttat ggtgatttgc ccagcaaatc
    82981 caaaacataa acaacgtcaa ggataattgg aggtgctata aatatggctc gtattgcagg
    83041 agtagatatt cctcgtgata aacgtgtagt agtttcactt acttatatct atggtattgg
    83101 taacactact gctaaaaaga tcttagctga tgctggtgta tctgaagatg ttcgcgttcg
    83161 tgaattaacg aatgaacaaa cagatgctat ccgtgcagaa gtagataaat taaaagttga
    83221 aggggatctt cgtcgtgaag tgaacttgaa catcaaacgt ttgatggaaa tcggttctta
    83281 ccgtggaatc cgtcatcgcc gtggattgcc tgttcgtgga caaaacacga aaaacaatgc
    83341 acgtactcgt aaaggcccag ctcgcgctat cgctggcaag aaaaaataat tcttaagtga
    83401 aggaggttaa aacttcatgg cagcaaaaaa agtgaatcgt aaacgccgtg tgaagaagaa
    83461 tatagaagca ggtattgcac atatccattc tacattcaat aacactatca tcatgatcac
    83521 tgatactcac ggaaatgcat tagcgtggtc atcagctggt tcattaggtt tcaaaggaag
    83581 caaaaaatca actccttttg ccgctcaaat ggcagcagaa actgctacaa aagcagcaat
    83641 ggaacacgga ttaaagactg ttgaagtaac agttaaagga cctggttctg gacgtgaagc
    83701 agcaattcgt tcattacaag ctacaggttt agaagtgact gcaattcgtg acgtgactcc
    83761 agttcctcat aatggtgccc gccctccaaa acgccgtcgt gtttaatgag tgccgctcat
    83821 tttgagtttt atcagtaacg tcattgaaca agacactttt cgttttgaaa ggggtaaaga
    83881 taagaatgat tgagttcgaa aaaccaagaa tcgcaaaaat tgatgaagaa aaagattatg
    83941 gcaagttcat cgttgaacct cttgaaagag ggtatgggac tactttaggg aattccctac
    84001 gtcgtatttt attatcttct ttgccaggtg ctgccatcac taatattcaa atcgatggtg
    84061 tactgcatga attctctacc atcaaaggtg ttagagaaga cgtcactcaa atcatcttga
    84121 acattaaagg cttagcgctg aaaatgtatg gccaagaaga aaaaaccctt gaaatcgata
    84181 ttaccggacc tgctacagta actgctggcg atattatcgt tgatagtgat gtagaaattc
    84241 ttaacaaaga tatgtacatc tgtagtgtct ctgaaggagc tacgttccat gctcgcttaa
    84301 cagtgaaacc tggacgtggt tatgttcaag cagatgaaaa taaaaaagaa gatatgccaa
    84361 ttggcgttct tccagtcgat tcaatctaca cacctgttcg tcgtgtgaac tatcaagttg
    84421 agaacacacg tgttggacac cgtgaagatt ttgataaatt gacgatggag atttggacag
    84481 atggttcaat tgaaccgttg gaagcaatga gtttgtctgc gaaaatcatg actgaacatt
    84541 tggatatttt tgtgaactta actgatgaag caaaaaatgc tgaaatcatg gtcgaaaaag
    84601 aagaaacaca aaaagaaaaa atgttggaaa tgacgatcga agagttagac ttgtctgttc
    84661 gctcttacaa ttgtttgaaa cgtgcaggaa tcaatactgt acaagaactt acaaataaat
    84721 ctgagcctga aatgatcaaa gtccgtaact taggacgtaa atcattagaa gaagttaaag
    84781 caaaattgca cgacttaggt ttaggtttac gtaaagaaga ttaaaacctt ttacgaagga
    84841 gggaaaccaa cgtgagttat cgtaaactag gacgcacatc tagccaacgt aaagcgatgt
    84901 tgcgtgattt aacaactgat ttattaatca acgaacgtat tgtgactact gaagctcgtg
    84961 cgaaagaagt tcgctcaact gcagaaaaaa tgatcacttt aggtaaacgc ggagatttgc
    85021 atgcacgtcg tcaagctgcg gctttcgtac gtaatgaagt tgccagcgtg cgtgaagaaa
    85081 atgaggacat cgtcattgaa tcagctttac aaaaactgtt caacgatatt gcacctcgtt
    85141 acgcagaacg tcaaggcgga tacacacgca ttttgaagac agaaccaaga cgcggtgatg
    85201 gtgcaccaat ggttgtctta gaacttgtct aaaatcacac taataacatc actttataga
    85261 tgattctttt agagtgttat gatgttggaa gatatttttc cgagtctagc tcagcgctgc
    85321 tcctcaagcg aatatcgctt ggggagtaag cactcatcat aaagtgtttt tttatacctt
    85381 caattacctg tcatgacaga tatgtttgaa ggcataaaaa aacattttaa gcgagaaata
    85441 attgaaaatt ttgtcttttt ttgatagtgt tagtaggaac tttaggatga agaaggagta
    85501 atcatggagc caattattga attagaaaag ataaattata aataccagcc agatgatctt
    85561 cgccccgcat tgaaagatgt ctcctttaca attgataaag gtgagtggat cgctattatt
    85621 ggacacaatg gttcaggaaa atcgacactt gccaaaacga tcaatggatt gcttctgcca
    85681 gaatcaggga tcgtgaaagt gggaaatcaa atattggatg aagaaaatat ttggacgatc
    85741 cgacagatgg ttggaatggt ttttcaaaat ccagacaatc agtttgttgg ttcgacagta
    85801 gaagatgacg ttgcttttgg tcttgaaaat caagggattc ccagagaaga aatgctagtg
    85861 cgtgtgaaag atgcacttga gaaagttaga atggctgagt ttgcttcacg cgagcctgct
    85921 cgtttatcag gagggcaaaa acaacgtgtt gccattgccg gcgtggttgc cttacgacct
    85981 gatatcatta ttttagatga agcaaccagt atgctagatc cagaaggtcg tgaagaagtg
    86041 atctctacga tcaagaagat caaagaagaa agtcaattga ccgttatatc tatcactcat
    86101 gatattgatg aagcagctaa tgccaatcgg atactagtga tgagacaagg cgaacttgtc
    86161 cgtgaaggta caccaaaaga aattttttct gctggtcctg aactgatcga cttaggtcta
    86221 gatctaccat ttcctgaaaa actgaagagc gcactgaaag aacgtggggt tgatgtgccc
    86281 agtgaatata tgacagaaga aaggatggtg gattggttat ggacatccgt tttgaacaag
    86341 tagacttcac ttatcagccg aatacaccat ttgaacaaag agccttattt gacatcaata
    86401 tgacgatcaa agaaaacagt tatactgcat tagtagggca taccggaagc gggaaatcaa
    86461 ccttacttca gcatttgaat gcgcttgtta agccaacaag cggtacagtc catattggag
    86521 aacgagatat tcagccggat acggataata agaatttaaa gcccatccga aaaaaagttg
    86581 gcatcgtctt tcagtttcca gaagcacagc tattcgaaga aacggtagca aaagacattg
    86641 ctttcggtcc taaaaacttt ggtgtcagcg aagaagaagc actagtccta gcaaaagaaa
    86701 cattagaaca agttgggctg gatgaaagct atttggaacg ttcgccattt gaactttcag
    86761 gagggcaaat gcgtagagta gcaatcgctg gtgtgcttgc catgaggccg gaagtacttg
    86821 tattggatga accaacggca ggacttgatc cccagggcag aaaagaaatg atggagatgt
    86881 tttggcgtct tcataaggaa cagcagatca ctattgtatt agttacgcat ttaatggatg
    86941 atgtagccaa ttttgcagat tatgtctatg tgttggaaaa gggacgaatc gttaatagcg
    87001 gggagccgca agaggtcttt caaaacattg aatggctaaa agaaaaacaa ctaggcgtac
    87061 ctactgccac cgagtttgca gaagaattaa tggctaaagg gatgaacttt gctaccttgc
    87121 ctttgacagc tgaagaatta gcagacgcta tcgtccatta tgctggagga aatgcccatg
    87181 atgaataaat tgatatttgg tcgttatatg cctggagatt ccttgatcca tcgattggat
    87241 ccccgagcta aattattagc cagtttttat tttatcggaa tcattttttt agcaaataat
    87301 tgggaaacgt accttttgtt ggcatttttc acattacttt ctgtcttctt gtcaaaagta
    87361 gatttgaaat tttttatccg aggcattcgc ccattgatct ggctaatcct cttcactgta
    87421 gctttgcagg tcttgtttac aagtggcgga gaaacttatt ggagttgggg tgttttccat
    87481 atcactgaat ttggtgtgat gaacggcctc tttattttct gtcgattcgt gttgatcatt
    87541 tttatgtcga ctctactcac gcttactaca ccgcctttgg aattatcgga tgcgattgag
    87601 tacttgcttc gtccattgaa agccgtacgg ttcccagtcc acgaaatttc attgatgctg
    87661 tcgattgctc ttcgttttgt gcctacattg atggacgaaa cagaaaagat catgaacgct
    87721 cagcgcgctc gcggtgttga ttttggtgaa ggaaacctag ttcagaaaat gaaagcagtc
    87781 attcctttgc tgattccttt atttgtcagc agcttcaacc gtgcggaaga tcttgcgact
    87841 gctatggaag caagaggcta caaaggtggg gaaggaagaa cgaaatatcg tgtattgcat
    87901 tggcataata gagacacgat ggttatcatt gcttttgtat tattaactgt gctactgatc
    87961 tttttaagag gataaacgtt cagtgggccg ctatctattc ttttcttgct gatctgtttg
    88021 caagaaagga tgcaagcagt gtatgacaag aaatattagg gtctgtggca gactaaggtc
    88081 acaggcctct ttcttttatc tgaaaagaaa gaacgaaaaa attttataga aaaatcatta
    88141 ttccagataa ccttttagga acaaaggaga gaaaaacatg gtacgttaca aagcaatcat
    88201 tgcgtacgac ggaacaaatt ttaatggatt ccaaaaacag ccaaatgggc gtactgttca
    88261 agaagaagta gaaaaaacat tacaaaaaat ggcaaatgga aaagaaatca cggtctttgg
    88321 ttcgggaagg acagatgccg gagtacatgc gatcgggcaa gtaatccatt ttgattatcc
    88381 agaggagcgt ccgttagaac gaatgcgttt cgcgctagat acccagtcac cagaggatat
    88441 tgctgtaaga caagtagaaa ttgtttcaga agacttccac gcaagatatt tggtcaaaga
    88501 aaagacgtat caatttcgag tggatatagg gaaaccacgc agtccttttc gacgccatta
    88561 tgcaagttat tttccttacc cacttgattt ggaaaaaatt cagcgggcgc ttcctgattt
    88621 attagggact cacgatttca cctctttttg tgcatcagga agctcgatag aggataaaat
    88681 acgtacgatc tacgaggcta agatggaggt aaatgaaaca aaagacgaat tgttgtttac
    88741 atttagggga aatggcttct tgtataagat gatacggatc ttagtaggaa cgcttttgaa
    88801 aattggcaat ggccgattgc ctgaagatag tatcccagat attattgcga aaaaagatcg
    88861 taatgcagca ggacctacag cacaccctga aggactttat ttgtatgaag tgaaatatga
    88921 ataagaggtt atgatagaag tggtcagctt caagaaataa gaaggtattt acgaaaatta
    88981 cttctcaaaa ttttgcaaaa tttcggctta ttttcgaaga agctacttct ggaacaccgt
    89041 ttaagaaaga ggtcgtgagc ctgtcattta actctgagtc acaaagagca atttcaaaaa
    89101 acagcttctc atctttgatg aatatcgtga cttgtggacg aggcgttgat aagtgaatca
    89161 tctttttgtt acctattttt tctgtaacca aaaaacgatg gaacgttgtt ttgattgccc
    89221 ttggtgcgga cagtctgaac aggttccatc gtttctttat tttctacgtc ttcttctgtg
    89281 tgtgtttcgt ggttgttctt ctattgctgg atcaatcgtg ccataaaagg ggcgattgcg
    89341 gtcaaggtac cagacataaa gaataaacaa tgcaatacat aggacaaaaa ggattgcacc
    89401 tatcgtaaat ccttcaggca agtaactgaa agtgacagta tgtttacctg ctggaacttt
    89461 tatcatcaag aatgcgtctt tgaaattgct gaccttgact ggtttcccat caattttagc
    89521 tttccatcct ttgtcataag gaatagttgt caccaacatg gaatcttcag cggtatttac
    89581 agtcccagaa gcttttctgc cagtggcttc catttcgaca cctttttctt tgatctgatt
    89641 cattgcggct tgataggcta caacatctag accaacgact ttaggctcca tgaaacttat
    89701 ttctttcgtc ccataaaaac ttgcagtaaa tgtcactgtt gtctcttgag gataatagcc
    89761 aagatcatag tattgaccag aaatgttgat ttgcgttttt cgcgatgtac cattgacagt
    89821 gatcgtcgca ctagaacttt ctaattgcgc aaaattggtt gggaacaaac ttaagtaagc
    89881 ttgtgtattt gcaggcacat ggacttccca agtgagctct tttggctggt tatctgctgt
    89941 ttctgagtaa gtgacgccag tcgttgtctt tgtgatcgtc gtattcaact gattcttcaa
    90001 agtaggtgta tagaatgtaa aatactgttc atttagacca gacaatgtat tgatcaagtt
    90061 tgtctgactg gtcaaattat ctgtcactgg ctgctcaaca tcattaacgg acaacggtgc
    90121 agtaaatgct agtggcaatg cattgacatt ctgatacagt gtatagtcgc cgctttgacc
    90181 agcttggcgg aagccatatt tactgaacgt gctttcgttt ttagaaatgt tatatttgat
    90241 tcctgtaaac ccatccatca gcaaagtatt attgttataa cggatattca aatttgtccc
    90301 tcttgaacgg aaacctaatt tatccaggta agaggaagaa ttacgatttc ttatagaaga
    90361 aaacaaactg ataccactgt aaccatagtt gatcgaatcg tttgcagata ctggatccag
    90421 attttccaag cggtaaaacg agtcggaatc tttttttgtt tcatttacaa gagctttcaa
    90481 gtcaggataa ggatcagtat ataaactgcg ggaagcataa ttccaatcat caagaatgcc
    90541 atggatcata ctgttcgtat tgaccagtgc ttcagcagac atgatcaata ataacaatat
    90601 actcagatga ttgaatgaaa gttttttatg ctgataaaat cccacagcaa aagcataaat
    90661 ccctaagaaa accactgtca atacaaagga agtcatcgtc acataggtgt agcttccttc
    90721 aggtttgatg ccccatgcca ccgcaaagag agcagctacg accaaaatga ttcctaacaa
    90781 cagcccacga tcgtcttgtt ctatcttttc ccatcctttt cctgcaagca ggagcactaa
    90841 gaaagagaac agataggcat aacggaataa aaacatattc ggtgcatgca taccatgcca
    90901 gaacaaattc aatggaacaa gataaaaact tgcgataagt atggcgaaaa gactgccgta
    90961 caaaaattta tttttcaacg gtactttccg actggcaaaa taaaacagac agaggactaa
    91021 tggtagcaga cctgcgtaaa cgaacggaat cgatccgtat tttgtcgtgt cataaacacc
    91081 aatcatattt ttcatgatta gatccagata agaagtcgct tctgttttca acgtagtgat
    91141 ctgactcagt gcctcgccat ttgaccgaag atccagcact gctggcaata caatgatcat
    91201 tgaagcgccg cctgccagta aagaagtgat accataagga acaatcgttt ttttatattc
    91261 tgaccagttt gtcaatagac gggcgataaa atataagaaa gaaaatacgc caatcataaa
    91321 acccatataa aaactggata aaaacaagag taaataactg ataaataaaa gtttcggccg
    91381 tttaagatcc ataacacgat gaatccccaa aatcactaat ggaagataaa caaatgcatc
    91441 cagccacatg atgatctccg aatgtgcagt gataaatgag atcaatgcgt aactgacgct
    91501 aagtgcaaca tgcccccagc gaggaatctt gaacgtacgt gcaagaaacc aaaaagccaa
    91561 tccggcacag ccgaccttaa gcaaagtcag aacatacagt gcatctggca tcatctggtt
    91621 tggaaaaaag aacaccagtg gcgtgaagat cccgcctaga tagtaagaaa ttaaagataa
    91681 ataattcaat cctagagaag cattccatgt ataaaaaata ctttgctttc caagaagaac
    91741 atttcggaag ctggcatgaa aattagaaaa ctgtgaaaag gcatcacttg ccaaaatact
    91801 tctgctgctt ccaggataga ttccgatact tagataaaca agtgctaaaa tcaaaaacgg
    91861 aatcaggaaa ctagctgctg cgtagcgtcc gttttctcta aagaatgact ttaaattttt
    91921 tttcatattt attttccacc aaatttctat gaagttgtat tcagtttatc atatccttgt
    91981 ttttctctgc ttaaaaagag tctagttttc acaaaaaaat aaaatttaga ataaataact
    92041 tcataatttg ttcgtataac aaaaataaac gcaaaaaaag ggtaggaatc aaaagtccca
    92101 cccttaaaaa tttttattaa ataaaaaacc gttcactatc tgaacggtcc aagtatcatt
    92161 caattaaacg cgttcaactt ttcctgattt caaagcacga gttgacaccc aaactttttt
    92221 aggttttccg tcgaccataa cgcgaacttt ttgtaagtta ggtttaacag tacgttttgt
    92281 tgagttcata gcgtgtgaac ggttgtttcc actttttgtc ttgcgacctg taaagtaaca
    92341 aacttttgcc atggtaattt cctcctttgc cttgatttgg agcaatagaa taattcagct
    92401 cataccagac taacatatca tatagaatgg gaatttgcaa gtacattttc atagatacaa
    92461 ttgacaattg agaagaataa ttgtaaatta aacaaggtta tacctgaaat tttgcaaggt
    92521 ttttgagtac tttgggtaac tgccttttat ttcaagttgc gctatgataa aatatgatag
    92581 aagaaaaatg ggagtttttt acccgttaag gaggctcatt catggctgta aaaattcaaa
    92641 cgtcagctgg aaccattgaa attaccaatg atgtaattgc aacagttgtt ggtggcgccg
    92701 cgacagatgt gttcggtgtt gtaggaatgg ccagcaaaaa tcaaattaaa gataatatta
    92761 ctgagatttt gcgtaaagaa aattactcaa gaggagtagt tgtccgccaa gaagataatg
    92821 gtattgctgt agatgtttat acgattatca gctatggtac gaaaatctct gaagtttccc
    92881 gcaacgtcca agaaaaagtg aaatacaatc tagaggcatt attaggcgta actgccaatt
    92941 cagttaatgt ctttgtacaa ggtgttcgtg tactgccaga ctaggcagga gactggctgg
    93001 taactcagca gtcgatctga aggaggatta tctaggtgag tgtaacagaa ataagtgcaa
    93061 gccagttcca ggaaatggtc caggcaggtg cgaatcgtct gcaagtaaat gcagaatacg
    93121 tcaattcatt aaatgtattc cctgtgccag atggcgatac gggaacaaat atgaatctat
    93181 ctatgactag tggagctaag gcagtagtag attcaacctc agaaaaagta ggagaattag
    93241 cagcaatgct ttcaaaagga ttgctgatgg gtgcgcgcgg aaattccggc gttattttgt
    93301 ctcaattgtt tcgtggattt tctaagcaaa ttccagatgt tgtctcatta aatgcttctg
    93361 atcttgctgc agccttcact catggagttg aaactgcgta taaagcagta atgaaaccag
    93421 tagaaggaac gattttgaca gtagctagag aagcagcgaa agctggagaa aagaaagcaa
    93481 aaagtactga tgatgtcgtt gaagtaatga cagctgttgt aaaaggagca aagcgtgctt
    93541 tagctaaaac tccagacttg cttccagtcc taaaagaagt cggtgtcgta gacagtggag
    93601 ggcaaggact gctgtttgtt tatgagggct ttttaagtgc attgaatgga gaattccaag
    93661 cggatgaaac atatgaacct tctccagcag aaatggatga tatggtcaat gcagaacatc
    93721 atcgcagtgt ccaaggtcaa atggcgacag aagatatcca ttttggttac tgtacagaaa
    93781 tcatggtaaa aatcggagaa ggacctacag tcgatagtac attcgattac gaagaattcc
    93841 gtaactattt agatggtata ggagattctt tacttgtggt caatgatgac gagatcatca
    93901 aagtccacgt gcatacagaa aacccaggag aagtcttgaa ttatggacaa aaattcggtt
    93961 cattagtcaa aatcaaagtc gacaacatgc gcttgcagca tgagacgatt ttggaacacg
    94021 atgaagaagt gaacgagttt gcgaaaaaag aaataccacg tatcccgtat ggtatcgtag
    94081 cgatcgctgc tggtaaaggc gtccaagagc tgtttgaaag tttaggcgct aattatgtta
    94141 tcagtggtgg acaaacaatg aatccaagta cggaagacat tgttaaagcg attcaagaag
    94201 taaacgcaga taaagtgatt gtcttgccaa acaataagaa catcttcatg gcagctgatc
    94261 aagcagcaga agtagcagat atcccagtag cagttgttcc ttcaagaacg atttcccaag
    94321 gattgacagc tatgctttca ttcaatgatc aagcttcttt agaagaaaac aaagaaacga
    94381 tgacagaaat gttgtctagc gttgtgagcg gtcaagtcac tcacgcgatc agagatacct
    94441 caattgacgg tgtagagatc aaagaaggag actttttggg catgatcgat ggaaaaatcc
    94501 tgatctctaa cccagatatc acagcaacag cgttaagtac actagaacaa atgatcaatg
    94561 aggacacaga gatcgtaacg atcttggcag gtgatgaagg aacagttgaa caagcaaatg
    94621 aatttgctga gaaactaaca gaaaaacatc ctgatttgga aatcgagatc caccaaggag
    94681 atcagcctgt ctatccttat ctattttctg ctgaataatt tctgtgtcag aatatctttc
    94741 taacacagta ttcattcata aaaggccttc ggttagtgat caggtatgat cgctgaccaa
    94801 gtcctttttt tgttaaagga gggaggaaaa atttatgcgt tctttagatg atccaatcac
    94861 tatgctggca ggagtcggag aaaaaagagc agctagtctt gccagcttgg gcatccaaac
    94921 gattgaagac ttactgactt attatccttt tcgctacgaa gatattcagg aaagaaatct
    94981 aaacgagatc caggatcaag aaaaggttac tttgaaagga atcgtagtct cgcctcctgt
    95041 gatgaatcga tttggttata aaaaaagccg attgcaattt cgtatgatgc aagaacatga
    95101 tgtgttcaac gtttcttttt ttaatcaacc ttatctaaaa gaaaaagtca ttttatcgga
    95161 ggaaatcgcc gtatacggta aatgggatgc aaagcgtaaa gccttgaacg ggatgaagat
    95221 tttaggttct caaacaatgg atgacttttc gccgatatat cacgtcaaca aatcaattcg
    95281 tcaaacgaca ttagttgatc taatcaaaaa agggtttcaa gaatacggca cattgattga
    95341 agaaaatctg ccaaacaacc ttgtggagaa atatcgactg cttgaccgag cttctgctgt
    95401 aagaagtatg cattttccaa aagaccacga agaaaaccat caagccaaac gacgtgtcgt
    95461 ttttgaagag ttctttttat ttcaaatgcg tcttcaagga ttgaaaaaag cagaaaaagc
    95521 agaaacgaat ggtttggaga tcctttatga tgtccaaaaa ttgaaacaat ttactcaaaa
    95581 gctacctttt gaactgacaa atgcacaaaa acgtgtaacg aatgaaatct gtcgggatct
    95641 tcgcagtccg cagcatatgc agcgactttt gcagggagat gtaggtagcg gaaaaacagt
    95701 ggttgccgcg attgcgttat acgctaccgt tacagcaggt ttccaaggtg cgttgatggt
    95761 gcctacagaa atcttggcac aacaacatat ggaaagcttg caacagctgt ttgatcccaa
    95821 tgaagtaacc atcgcattga ttacggggtc aacgaaagca aaagaacgac gtgagctcct
    95881 tgaaaaacta gagcaagggg aaattaacgt cgtgatcggc acacatgcat tgatccaaga
    95941 tggagtcgaa tttcagaatt taggtctagt tattacggat gagcagcacc gttttggcgt
    96001 gaaccagcgg aaagtacttc gtgaaaaagg ctggcgacca gatgtcttat ttatgacagc
    96061 gactccgatt cctagaacat tagctattac agcatatggt gagatggatg tatctatcat
    96121 tgatgaactt ccagctggac gtatcccgat cgaaacacgc tgggtaagaa cacctcaatt
    96181 ggacagtgta ctggattgga cgaaaaaaga actggcaaga ggacatcaaa tgtatgtcat
    96241 ctgtccgctg attgaagaat cagaagcatt agatgtaaaa aatgcagtgg aaatctatga
    96301 aaaacttcgt gaactatttg caccaaaata tgaagttggc ttgttacatg gtaaaatgaa
    96361 gaatcaggaa aaagaagtaa tcatggaagc cttcaaagac aaccagatgc agatattagt
    96421 ttcgactact gtaattgaag taggggtaaa cgtgccgaac gcgaccgtca tgctgatcat
    96481 ggatgcggat cgatttggat tggcacagct gcaccaactt cgtggacgtg ttggacgcgg
    96541 aagtgatgct tcctactgta tcttagttgc taatcctaaa aatgaactag gtgtggaacg
    96601 gatgaaaatc atgacagaga ccaccaatgg ttttgtacta agcgaaaaag atctggaatt
    96661 acgtggtcct ggtgaagtat ttggcttccg tcaatctggt ctgcctcaat ttgcgattgc
    96721 tgacttggtg acggatggaa atgttttgga ggtagccaga gaagaggctg cagccctttg
    96781 gcaaataaag gattggcaga tgcttcctga gtatcagcct ttagcgcaaa gcctccaaat
    96841 agaaaatcag gataatcgtt atttcgatta gcagactgtg ctatacttta tactgatgac
    96901 ggaaaaagga gtggaaacaa tgaaaattgc cgtagatgca atgggcggag atcacgcacc
    96961 tcaagcaatt gtagaaggcg tggctttagc gcagcaagat tttccagaag tagaattctt
    97021 actttacgga aaagaagcag aaatcaagaa atacttaaca aatgaaaaaa acatcacgat
    97081 tatccataca gacgaaaaaa tcaatagtga tgatgagcca gtaaaagcaa ttcgacgaaa
    97141 aaagactgca tcaatggtcc ttgctgcaca agcagtgaaa aacggtgaag cagatgctgt
    97201 attttcagca gggaatacag gcgcgctact agcagcaggg ttgttcatcg taggacgtat
    97261 caaaaatatc gaacgccctg gcttgatgtc taccttgcca gtagtaggga aagaaggtgc
    97321 cggtttcgat atgctggatc ttggcgctaa cgcagaaaac aaaccagaac atttgttgca
    97381 atacggtatt ttaggttctt tttatgcacg taaagtccga ggtatcggac gtcctcgtgt
    97441 cgcactctta aacaacggaa cagaagcaac aaaaggtagt gaagtgacga aaaaagccta
    97501 tgaactcctt cagaatgaaa caagcttgaa ttttattgga aacgtagaag ctcgtgagct
    97561 actcaatggt gtggctgatg tagtggtcac agatggattt acaggcaacg ctgttttgaa
    97621 atctattgaa ggaacagcaa tgaatatgat gaatctatta aaatctgcta ttctaaatga
    97681 agggatcaaa ggaaaaatgg gcgctatgct tttaaaagac ggcttacgtt ctttgaaagc
    97741 agaaatggat tattccaaac atggcggtgc cgttttgttt ggcttgaaag caccagtcat
    97801 taaaactcat ggagcaacag gccccgatgc tgttcgctat acgatccgcc aaatccacac
    97861 aatgcttgag acagatgtag ttggacaatt agtcgaacaa tttgaaaaaa gcgaagaata
    97921 gtatttggat atctgaagcg atccgttcca ttgaaaaaaa ggtggacatt cctgaaaaat
    97981 gccagtaaaa ttagccatgg tgtaggtaat tgacaagtgt atgattcttg gaggtgaaaa
    98041 agttgactcg cgaagaagta tttaacaaag tagcgaaaat tatttcaaat cattttgaga
    98101 tagataccga taaagtgacg gatgaattga acatcaaaga tgatttaaaa gctgattcaa
    98161 ttagtattat ggaattcgtt ttagagcttg aagatgaatt cggtacggaa atttcagatg
    98221 aagacgctga acaaattgaa acagtcggtg gcgcagtaga ttatatcagc agccatctta
    98281 aataatttca aataaaagca aagaaggata aaaagctgca tgcagctttt tatccttctt
    98341 tttttaatct ttttgacacg taaaagtcat ttttctgata attctggcga taaacagaaa
    98401 ttatgttgca aagtaaagcg gttttctata taa
//
LOCUS       DAFBVQ010000004        93454 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.004, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000004 DAFBVQ010000000
VERSION     DAFBVQ010000004.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 93454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 93454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..93454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.004"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            83..970
                     /locus_tag="LLC22_000308"
     CDS             83..970
                     /locus_tag="LLC22_000308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK5433616.1"
                     /translation="MQELKTRSARHHRPKRKMVINKKAIAPLIGTSLLVGPMMVTAVP
                     QHVHADEQGSQTVADPQAFIDQIGWSASEVAASNDLYASVMIAQALLESAYGTSGLAS
                     APNYNLFGVKGSYNGQVVYMATKEYVNGQWVTMNEPFRKYSSYWESFQDHANVLRSTS
                     FSTGDYHYAGVWKSNTTSFYDATAYLTGRYATDPNYGAKLNSLINTYNLTRFDTPSTG
                     SATTTTSTTTTTTTTTSTSSSSTTDVNTNNGQTYTVVSGDTLWDIAQKFGMSVDDLMA
                     KNGMSMSSYSLLVGQELNV"
     gene            1110..2036
                     /gene="cysK"
                     /locus_tag="LLC22_000309"
     CDS             1110..2036
                     /gene="cysK"
                     /locus_tag="LLC22_000309"
                     /EC_number="2.5.1.47"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase A"
                     /protein_id="HBK5433617.1"
                     /translation="MTAIYNSVTELIGKTPIVKLNKIVPEDSADVFVKLEFFNPGGSV
                     KDRIALSMIEKAEHDGLLKPGDTIIEPTSGNTGIGLSMVGVAKGYKVIIVMPETMSIE
                     RRLLMKGYGAELILTPGADGISGSIREAERLAKENGYFLPLQFENEANPLVHEKTTGP
                     EIHQAFGVNGLDAFVAGIGTGGTITGAGRELKRVYPKIELIGVEPAESAILEGKEAGP
                     HKIQGIGTGFVPKTLDTSVYDKVLSISGDEAMETAREVGRKEGILVGISSGAAIAAAL
                     KVAKELGKGKKVLAVVPDNGERYLSTALYQEI"
     gene            2272..2718
                     /locus_tag="LLC22_000310"
     CDS             2272..2718
                     /locus_tag="LLC22_000310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289542.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK5433618.1"
                     /translation="MENKLVEEVIEKLKKENIRITPQRYAVLEYLIEHHSHPTADEIY
                     KALEHRFPNMSVATVYNNLRLFTSIGFVQEMKYGDASSRFDFSSKRHYHVICENCGKI
                     VDFHYPGLEDIEMAASRLTDFEINEHRLELYGLCPDCKESAKKAQM"
     gene            2991..4343
                     /locus_tag="LLC22_000311"
     CDS             2991..4343
                     /locus_tag="LLC22_000311"
                     /EC_number="7.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289543.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADH oxidase"
                     /protein_id="HBK5433619.1"
                     /translation="MKVVVIGCTHAGTAAVKSILKNHPEAEVTVYERNDNISFLSCGI
                     ALYVGGVVKDPAGLFYSNPEELSSLGATVKMEHDVTDVDTENKTVTAKDLKTGETETV
                     SYDKLVMTTGSWPIIPPISGIDAKNVLLCKNYNQANEIIAQAKEAKRVVIVGGGYIGI
                     ELVEAFVESGKQVTLIDGLDRILNKYLDKPFTDILEKELTDRGVTLALGENVTEFITD
                     EEGKVKQVATPTDTFDTDMVILCVGFRPNTKLIEGKVDTLPNGAIKVNEYMQTSNPDI
                     FAAGDSAVVNYNPSGTQNYIPLATNAVRQGLLVGNNLTDHKMAYRGTQGTSGLYLFGW
                     TIGSTGVTKESATLNDLEVQATVFEDNYRPEFMPTTEKVMMELVYEKGTNRIVGAQFM
                     SKYDITQSANTMSLAVQNKMTVEDLALSDFFFQPHFDRPWNYLNLLAQAALGEIETAQ
                     "
     gene            4514..4801
                     /locus_tag="LLC22_000312"
     CDS             4514..4801
                     /locus_tag="LLC22_000312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433620.1"
                     /translation="MNKEYFVQQDAFLEDYKSASKKLTINIDELADQVLSQLNETQEE
                     YYTMPANDAKDNVSHRFPFSRRIYSDENDGTLNTEYTYEGQPYVLETDDDL"
     gene            5027..5470
                     /locus_tag="LLC22_000313"
     CDS             5027..5470
                     /locus_tag="LLC22_000313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5433621.1"
                     /translation="MDKRQLLIEEYLDLANEIIHRNKPEMEKEFAGFTLNELEVIEHI
                     GKIPDPNVTKLANASYMTRGAISKLTKKLIARGIINTYQSEENKKEIYFQLTPIGQKI
                     RNRHEQLHQKWVQRDATVFENMSKEEFDTVFRFIGRYREFIRSSK"
     gene            complement(5476..6660)
                     /locus_tag="LLC22_000314"
     CDS             complement(5476..6660)
                     /locus_tag="LLC22_000314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5433622.1"
                     /translation="MYSFTNKHSKVFGYVSVLFTGLGFTIVSPVLPFLTLPYSHSIHQ
                     QAFYITLLMSVYALAAFLSAPILGSLSDHFGRHPILIISLLGSSIGYLLFGLGNSIWM
                     LFLGRIIEGLTAGEISTLYAYFADITEPNERTKVFGWMGALVGIGTTLGPIIGGLLAE
                     LGNSVPIFIGALFTFLNAVYGYTFMLESLPIKKRSVDLSFSHVRPFHQLQQLFKISSV
                     IPLLTAGCAVWLAAGSLQSIFSQFSIDAFQWKAGLVGLSFSLIGILDTVSQLFIMPRL
                     LKKFSEQQITRIGMFSEILAYLFITLSGILLLPILFLFGIICYGFGDSIFTPVFNGQL
                     SNSVSDNQQGLVMGGTQSIQSLSRVIGPLIAGQLYAAAPFLPTVFGFLLMIFAYYHYN
                     KK"
     gene            6928..7626
                     /locus_tag="LLC22_000315"
     CDS             6928..7626
                     /locus_tag="LLC22_000315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBK5433623.1"
                     /translation="MLNLENYLSAGQTVISNLLLKNYHRIGLQSEEFLFVLQLHMAQL
                     EGDTFPDLQMIAMDMGIKQDQIFQILDRLVTNGFIKIETTIVNGKKADRYNLYPIYDL
                     LGEYLKTQEKKYEEKTQEKEIQSVYQLFEQEFGRPLSSIEFQRIGQWLEEDHYQPEIL
                     KLALREAVLNQAYSFNYVDRILLSWERKNLRTKQQVEEDQKRRKQQLLQREVEQSAQQ
                     EELPKVSLKNWLEE"
     gene            7633..8310
                     /gene="nth"
                     /locus_tag="LLC22_000316"
     CDS             7633..8310
                     /gene="nth"
                     /locus_tag="LLC22_000316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease III"
                     /protein_id="HBK5433624.1"
                     /translation="MLSKQKTMEALETMYGMFPEAHGELKHNNPFELLIAVILSAQAT
                     DVSVNKATPDLFASFPTPDALAEASIDEIILKIKTIGLYRNKAKNIKACAQQLIERFD
                     GQVPTSREELMSLPGVGRKTANVVLGDAFGIPAIAVDTHVERVSKRLRICKLDATVME
                     VEETLMRKVPQELWVKTHHTLIFFGRYHCTARNPKCEVCPLLSICQDGKNRMRLKEKA
                     LKKKPRL"
     gene            complement(8436..8969)
                     /locus_tag="LLC22_000317"
     CDS             complement(8436..8969)
                     /locus_tag="LLC22_000317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433625.1"
                     /translation="MVLNNFLKEGFILSYLIVCLIIIICLHHLFLSKTIPRYSKNKKA
                     EKFCLLLNKFTLIAPILAFIIFSVLLSTTLKGKFMERSSHAMILTFLWLLFTRIYIFL
                     MSLKPPKSISLCLVINGIFLLSLIIFITPLDRYVTYLYNPLEYWTYFIGILEGIIFYI
                     GYFPNKNNNFYFYRNKL"
     gene            complement(9266..11647)
                     /locus_tag="LLC22_000318"
     CDS             complement(9266..11647)
                     /locus_tag="LLC22_000318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBK5433626.1"
                     /translation="MANEQTRSSRRQKQPTPKKSVKKNSGKGSGKSSGTHKKGLFIKI
                     LLGILSFFCILFLAGVGLFWYYAKDAPELTDKKLDATVSSKLYTQDGELFEDLGAEKR
                     EKISANELPKTLEDAIVSVEDRRFYKHIGVDPIRIIGSALSNFTSGGLQGGSTLTQQL
                     IKLSFFSTSAEDQTLKRKAQEAWMAVRLEQKKSKQEILTYYVNKVYMSNGLYGMETAS
                     EMYFGKKLSELSLPQTALLAGMPQAPSAYDPYVYPDQAKKRRDTVLYTMLQNEKISQT
                     EYDQAVNVPVTDGLQELTQSDDNTKIVDNYVKEVINEVQEKTDKNVYTDGLEIYTNLD
                     LDAQKKLYDIVNTDQYVSYPDDEMQVASTLIDTNTGKVKAQIGGRHIAEDVTLGNNLA
                     VNTSRDFGSTMKPVTDYGPAFEYLKYSTGKTITDAPYNYEGTSTPVGNWDNQYMGTIT
                     LRQALYLSRNVPAVKLFNEVGSDKVASFLKNLGIEYSTIHQSNAISSNTEEQDGTKYG
                     ASSLKMAAAYAAFANGGTYYKPQYVNKIVFQDGTEETYEPDGKTAMSPETAYMITDIL
                     KDTITEGTGTNAQIAGLYQAGKTGTSNYTDDEYAKLGISSGVYPDILFAGYTPNYSIS
                     VWTGYNKKMTPVTSESSHVASDVYRELMQYVSANVTNTDWEMPSGLIRVGGELYYKDQ
                     YTARSNAITPSTTIPSSSYVQTPGSSTTETTTQSSSSTSQSESTAESSKESTTAETSE
                     PASSTTVPSSSSEESSTPSSSAPPASSSEPATSGADAANDHTPSSSTSASGNR"
     gene            complement(11637..12284)
                     /gene="recU"
                     /locus_tag="LLC22_000319"
     CDS             complement(11637..12284)
                     /gene="recU"
                     /locus_tag="LLC22_000319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RecU"
                     /protein_id="HBK5433627.1"
                     /translation="MVLRYPNGQPYYKNASPVEKIQEKRNQITEFGNRGMRFEEAINE
                     SNKYYLSRGLAVIHKKPTPIQIVKVDYPKRSAAVIKEAYFTQASTTDYNGVYRGFYLD
                     FEAKETKNKTSFPFKNFHAHQIEHMKACLEQNGVCFVLLWFSSLKRCFYLNSVHLIAY
                     WDAQKEKGRKSLPLSLIEELGIEIKTGISPRIPYLDAVDFYLSTLSIEGESKNGK"
     gene            12348..12887
                     /locus_tag="LLC22_000320"
     CDS             12348..12887
                     /locus_tag="LLC22_000320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1273 domain-containing protein"
                     /protein_id="HBK5433628.1"
                     /translation="MDKSKVIYVSGYRSFELGVFKENDPKIQVVKNVLKKELHQLAEE
                     GLEWVLVSGNLGVELWAVQIVAELKEEYPELSLGILYPFSDFGNNWNEGNQEKKQLAE
                     QLADYVEAVSHQPYQSPSQLKNHTRFILEHTVGCLLIYDEEFPGKTKYFFEDAQNYQA
                     DHPYEIRLISMDDLQNFSE"
     gene            12977..13396
                     /gene="gpsB"
                     /locus_tag="LLC22_000321"
     CDS             12977..13396
                     /gene="gpsB"
                     /locus_tag="LLC22_000321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division regulator GpsB"
                     /protein_id="HBK5433629.1"
                     /translation="MANLVYSPKDILQQEFKTKMRGYDPVEVDEFLDNIIKDYETYSK
                     ELLALQEENDRLSAKVAQLSKTQGAAQTRVQQTEAPKSAAVTNFDILKRLSNLEREVF
                     GKKLDQQASAVKPAQPNPNNYTNADTSLDDNEKTRQF"
     gene            13418..13785
                     /gene="rnpB"
                     /locus_tag="LLC22_000322"
     ncRNA           13418..13785
                     /ncRNA_class="RNase_P_RNA"
                     /gene="rnpB"
                     /locus_tag="LLC22_000322"
                     /product="RNase P RNA component class B"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00011"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00011"
     gene            13994..15160
                     /locus_tag="LLC22_000323"
     CDS             13994..15160
                     /locus_tag="LLC22_000323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent RNA methyltransferase"
                     /protein_id="HBK5433630.1"
                     /translation="MEKNRKFNLVATAASGLEALVGKELRDLGIECQVENGRARFEGT
                     METIATANLWLRTADRVKIVVGEFDAYTFDELFENVKALPWEDFLPLDAAFPVAGKSI
                     KSKLYSTPDCQAITKKAIVERLRTYYHRPASVPLTETGAHFQLEVALLKDHVMVTLDT
                     TGPSLFKRGYRLEKGGAPLKENMAAALIMLTNWRKDRPFYDPVCGSGTLCIEAALIGH
                     NIAPGFNREFACESWDWFSQEIMENVRSAAEEKADYDIELDITGSDINGRMIEIAKAN
                     AEEIGLGSSITFKQQAVKDFKTDKEYGVIVANPPYGERLGEEETVRKLYKEMGDVFRP
                     LKTWSKYILTSDLAFEEFYGQKATKKRKLYNGALRTDLFQYWGTRPPRKKEKDE"
     gene            15206..16702
                     /locus_tag="LLC22_000324"
     CDS             15206..16702
                     /locus_tag="LLC22_000324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxypeptidase M32"
                     /protein_id="HBK5433631.1"
                     /translation="MKEKEFLQEVKEINLLQQALGILDWDTQTGMPEKASAYRSEVDS
                     YLYSIYFSKKIGPKIKEAIRYFSEHPEELSEVGTAVFAKVKEEYDLEHRVPEDLMRKY
                     TAAVSSAHGQWQKARETQQFSDFQHALNQNIELTKQLIPYWRKDEKTNYDVLLNQYEP
                     GMTVEILDKVFDQLKEGILSIRRTLQEKGTEPETDFLNRRMTKKQQKRFVVKVIEQLG
                     YDFSRGRLDDTVHPFMTGINPNDARITTRWNETDFKMAVFGVIHEAGHGMYEQDIDDK
                     YAYTPVYEGTSMGIHESQSLFNEIIIGSSRSFWKKQYPFFQECAEGTFDDIPFDKFYR
                     SLNHTKSSLVRIEADSLTYPLHIIIRYEIEKMIFNEGVDVAELPEIWNQKYEEYLGIR
                     PTNDVEGILQDVHWSGASFGYFPSYALGYMYAAQLLHSLQQEIDVENVLASDDYSPIK
                     NWMSEHIHQYGASRKPNQLIMDATHEPLNPQYLIDYMKDLYFNVYQVK"
     gene            16783..17466
                     /locus_tag="LLC22_000325"
     CDS             16783..17466
                     /locus_tag="LLC22_000325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5433632.1"
                     /translation="MDKLQVIADYSMDQLAHDQTGHGSDHTKRVVKLAEKILETEPQA
                     DRFVTLAAAYLHDTIDDKVVKNENEAKQQLRVFLRSLPIVEEQISMIFSIIENMSFSK
                     NLSEAAELSLEGKIVQDADRIEALGAIGILRTAYFGGGHGHPIFDPELYPQTFKDKEN
                     YRKGTTVINHFYEKLFLLSDKMNTDYGYEEAKRRETFMREFLEEFFLEWSIDDENFTP
                     DNWIKNNKK"
     gene            18111..19301
                     /locus_tag="LLC22_000326"
     CDS             18111..19301
                     /locus_tag="LLC22_000326"
                     /EC_number="2.3.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine C-acetyltransferase"
                     /protein_id="HBK5433633.1"
                     /translation="MSSKELTMYLEKELDQLKEKGLYNTIDILESENGACIIVDGKKM
                     INLASNNYLGFANREELKKACIEATETYGVGAGAVRTINGSLKIHQQLEEKIAEFKGT
                     EAAIAFQSGFNCNMGAISAVMTKEDAILSDELNHASIIDGCRLSGAKIIRIKHQDMKD
                     LEKKAKEAIESKKYKKIMYITDGVFSMDGDIARLPEIIPIVEKYGLITYVDDAHGSGV
                     TGKGAGTVKHFGLSDKIDMQMGTLSKAIGVVGGYVAGSKTLIDWLKARSRPFLFSTSL
                     TPGAAAAALASITLMQEHPELVEKVWENANYFKEELKKVGYNIGMSETPITPVILGDE
                     KVTQTFSKKLIEHGIYAKPIVYPTVPLGTGRIRNMPTAEHTREMLDEAVAVYQKIGKE
                     MEII"
     gene            19403..20356
                     /locus_tag="LLC22_000327"
     CDS             19403..20356
                     /locus_tag="LLC22_000327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-threonine 3-dehydrogenase"
                     /protein_id="HBK5433634.1"
                     /translation="MKKVLVTGCLGQIGSELITRLRQELGSENVIATDIRMPEVIEKN
                     DIFEILDVMDYEKMRSIAEQYQVDTLIHLAALLSAVAEAKPQLAWNLNVTGLVNALEV
                     AREFQLKFFTPSSIGAFGPNTPKDHTPQDTLQRPTTMYGVTKVAGELLCDYYYVKYGV
                     DTRGVRFPGLISYATLPGGGTTDYAVDIYYSAIKEGKYTSFIDQGTSMDMMYMPDAID
                     AIIKLMNADPDRLVHRNAFNISAMSFDPEEIKASIQKIIPDFEMDYDVDPVRQSIAES
                     WPNSLDVSCAQEEWGFSPKYDLDVMTKDMLEKLKEKLVETV"
     gene            20425..21774
                     /locus_tag="LLC22_000328"
     CDS             20425..21774
                     /locus_tag="LLC22_000328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5433635.1"
                     /translation="MEEYQATPVKEVKIENELKRTMGFFTALSTVMGTVIGAGVFFKA
                     ASVAEVTGSASLHMFSWFLGGMISVCAGLTGAELAAAIPETGGMIKYIERIYGNTAAF
                     LLGWAQVVIYFPANVAALSIIFGTQFVNLFGLSQSMIVPVAVTAAVSILLINFLGSKA
                     GGAFQSITLVCKLIPLFVIVIFGLFRQEGVDFQLFPIQAGENLSFFSALGAGLLATMF
                     AYDGWIHVGNISGELKKPAKDLPKAISLGIIGIMIVYLLVNAVFLRTASIDGVAGNSN
                     AASDVAKMIFGGFGGRLVTVGILISVYGTINGYTLTGMRLPYVMAKENNLPFSKLFAK
                     LHDKTKVPVAAGILELVIAIGMMMIGGFDTLTDMLIFVIWIFYTMVFVGVILLRKKEP
                     DLFRPYKVPMYPFIPLVAIIGGTFIVSSTLITQTFLASMGIVLTLAGIPIYLYLKRR"
     gene            complement(21957..22280)
                     /locus_tag="LLC22_000329"
     CDS             complement(21957..22280)
                     /locus_tag="LLC22_000329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289192.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433636.1"
                     /translation="MLNMYFVFGVPIFLLFLYATIAYVRKRTTIHYLGFILLIISGFM
                     LVFNLQTWQQALLEMDKMTPHALSKVLGYPVYLIWLPIFISGCLVLLNIYRGVRRIVQ
                     LRKSK"
     gene            22409..23572
                     /locus_tag="LLC22_000330"
     CDS             22409..23572
                     /locus_tag="LLC22_000330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBK5433637.1"
                     /translation="MASYIEPIRFALIVFPFLALAISSVFFIYEYRKYGTFLVTRAVI
                     LYSFVFYLLCAYFLVILPLPAKETVAQMTGPKMELHLFASWQHFRDNTVLVLSEPSTY
                     LPAMKQSVFLEPAFNVLLLIPFGIYLRYYFRLSFMKTMIASFCLSLFFELTQLSGLYF
                     IYPRPYRLFDVNDLVTNTLGGIIGFVVTPLFTFMLPTRRRMDELSYEKGKTVSLTRRL
                     VAYLIDWTFLSLINLVAAIFFKIAFDSGAVTSHIWWLLLEVGVYFMIVPFITNGWTLG
                     KKIVRIRLVEEDRERISLKALMIRYGYLYFLFYGLSWLGQLLQQIMNSTTNTVLQMSA
                     VFISLGVLLLQGIFILNILLSFLRKKRILFYEKASHTYTVSTIGQTKDDDSRN"
     gene            23642..24991
                     /locus_tag="LLC22_000331"
     CDS             23642..24991
                     /locus_tag="LLC22_000331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK5433638.1"
                     /translation="MNNFDIFRFKPFINEALTAKGFKQPTEVQERLIPLIAKGKNIIG
                     QSQTGTGKTHTFLLPLFEKINAEKEEVQVVITAPSRELAAQIYEAATQIAKFSTPEIR
                     VSNFVGGTDKQRQLNRLHHQQPQVVVGTPGRILDMMNEQALKIHTAFAFVVDEADMTL
                     DMGFLNEVDQIASRLPEKLQFLVFSATIPEKLRPFLRKYMENPIIEEIKPKAVISEDI
                     ENWLISTKGKDENQMIYQLLTIGHPYLAIVFANTKQHVDEIADYLKNQGLKVAKIHGD
                     ITPRERKRVMRQVQNLEYQYVVATDLAARGIDIEGVSHVINAEIPEDLDFFIHRVGRT
                     GRNGLKGTAITLYSPNDEQAIDAIEKLGVSFEPKEIKNGEIVKTYDRNRRAKREKSKD
                     VLDPTLIGLVKKKKKKIKPGYKKKIDWAIAEKNKKERKIERRQQSRTARKNKKNSHK"
     gene            complement(25036..25467)
                     /locus_tag="LLC22_000332"
     CDS             complement(25036..25467)
                     /locus_tag="LLC22_000332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5433639.1"
                     /translation="MKKIVGADEWIRAASCFLRYQVFVLEQGIPAELEFDGKDIPQQT
                     YYLFLDQKRPVATLRYEKKTPTCFKPERFCVAKEYRGKGLGGQLLEAAEKRAVSEGCQ
                     TSYVVAEMTAVDFYEKQGYHTCTEPFIEDEVLCIGMKKSLA"
     gene            25855..28497
                     /gene="alaS"
                     /locus_tag="LLC22_000333"
     CDS             25855..28497
                     /gene="alaS"
                     /locus_tag="LLC22_000333"
                     /EC_number="6.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine--tRNA ligase"
                     /protein_id="HBK5433640.1"
                     /translation="MKQLSSAQVRQMFLDFFQSKGHTIEPSASLIPVNDPTLLWINSG
                     VATLKKYFDGSVVPENPRITNAQKSIRTNDIENVGKTARHHTMFEMLGNFSIGDYFKN
                     EAIHWAWEFLTDPKWMAFDPEKLYVTVYPKDTEAKRIWHEEVGLPLDHIIDVEDNFWD
                     IGAGPCGPDTEIFYDRGEAYNDLAEDDPENYPGGENERYLEIWNLVFSEFNHKPDNTF
                     EPLPHKNIDTGMGLERMVSIVQDASTNFETDLFMPIIHAVEKLSKQVKYGENPVTDIS
                     YKVIADHIRALSFAIGDGALPSNEGRGYVLRRLLRRAVMHGKKLGIEQAFLYRLVPVV
                     GEIMVSYYPEVLQQKEFIEKVIRTEEERFNETINEGLEILNQVIQEVKNENGTTLAGK
                     DIFKLYDTYGFPVELTEEVAEDEGLKVDHAGFEKEMDAQRERARSARSTEKSMGVQSA
                     LLTDIKVESKFIGYTEQESDSQLLVIVKGESLLNEVAEGEAQMIFDQTPFYAEMGGQV
                     ADQGWIMNEVGEIVAVVTDVQKAPNGQFMHTVEVKAPMSEGQTYHLLIDQSMRNRIIK
                     NHTATHLLHKALKEVLGEHANQAGSLVAPGHLRFDFTHFGQITSDELAEMERIVNEKI
                     WEAIPVETIETDIDTAKNMGAMALFGEKYGHDVRVVNIGGWSIELCGGTHVANTENIG
                     IFKIVSESGIGAGVRRIEAVTSKEAYELLEEEEKQLKQVATIVKSPQLKEVVSKAEQL
                     QQQVRELQKENEQLASKLANQQAGDVFKDPETINGKTIIAAQVKVKDMNQLRQLADQW
                     KQKNISDILVLANEQEGKVSLLAAMTKESNEAGLKAGDLIKAIAPKVGGGGGGRPDMA
                     QAGGKNPAGIPDALKAAKEWVAQQ"
     gene            28697..29293
                     /locus_tag="LLC22_000334"
     CDS             28697..29293
                     /locus_tag="LLC22_000334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5433641.1"
                     /translation="MNSRNKTFRLVLRAILLAIIIVQAMVPWLGFIPLGFISLTIIHI
                     TVIIAAVVLGPKDGMVIGLFWGIATIVRAYAMPTTPFDTLVFTNPIISVVPRVLVGLV
                     AGLVFHWIYQKNKSITISSAFAGVLGSLVNTVLVLGFMGLFYTGATADAYGVDSALLF
                     KTLAGVAAINGIPEAIGAGIITPLLAKALFAATPLKPE"
     gene            29415..30563
                     /locus_tag="LLC22_000335"
     CDS             29415..30563
                     /locus_tag="LLC22_000335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311124.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK5433642.1"
                     /translation="MAKKQEEKKKQIPQQRTKKGVLAGILGLVTNLILFVSKLMIGLF
                     SGSVSIMADAVNSLSDTASSILTLIGFKIAAKPADQEHPYGHERFEYISGLFVSIIIT
                     YVGFQFLESSAEKIIHPENVSLTPIVFFVLIISIFLKFAQGKMYQVIAQSIDSETLRA
                     TATDSYNDVFTTLAVLLSAAIEWVTGWRIDGYIGFALALYILYSGLTMLRNFVYELLG
                     SRPTPAEIEEMEEHLNACDDILGYHDLLVHNYGPNKRFASVHIEVDESMNLNVAHKII
                     DLIEKDFKKSLDVELVCHLDPMPVDNEKYYNILRQLKQILLETGTGLNIHDFRVIHQG
                     KTLQFDVVVPEKFQFVDTELERILRSQIEEKIGDYQLEITFDHNYLLY"
     gene            complement(30601..31014)
                     /locus_tag="LLC22_000336"
     CDS             complement(30601..31014)
                     /locus_tag="LLC22_000336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HI family protein"
                     /protein_id="HBK5433643.1"
                     /translation="MLKVYIDASTKGNPGPSGGGILIVYQGKQEQLSIPLSIGTNHQA
                     EFEVFLKTLEFLKKNDLQNETIFCFSDSKTLVSTVDKNATKNELFLPYLQRIQELLSE
                     FSLLILQWLPENKNKGADNLARQALHKQLKEKKTL"
     gene            31093..31524
                     /locus_tag="LLC22_000337"
     CDS             31093..31524
                     /locus_tag="LLC22_000337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EbsA family protein"
                     /protein_id="HBK5433644.1"
                     /translation="MKKNIRWQPELAHTIIYWSLTLIILFFSLILSLENTGPYWKSNF
                     VLGIFLVFLFLGLRRSFILKSNSVIIRYAAFWKDREISVGQIRSLTPTNTGVQMMLQD
                     EKAPSVFMMRKKDQVVLFDHFEKNGPKSESIPYPYTKKRKS"
     gene            complement(31623..31856)
                     /locus_tag="LLC22_000338"
     CDS             complement(31623..31856)
                     /locus_tag="LLC22_000338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold shock domain-containing protein"
                     /protein_id="HBK5433645.1"
                     /translation="MTTGIVKWFDNKKGYGFISYDDTEEIFVHFTAIEEEGFKTLEEN
                     QVVEFEIIEGNRGTQAAHVKKGNVQTTDTSMHE"
     gene            32039..33709
                     /locus_tag="LLC22_000339"
     CDS             32039..33709
                     /locus_tag="LLC22_000339"
                     /EC_number="6.3.4.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate--tetrahydrofolate ligase"
                     /protein_id="HBK5433646.1"
                     /translation="MKNDLQISQETELEPIVEVASKLDLKEDDLELYGKYKAKINFSG
                     INRSKDNAEGHLILVTSINPTPAGEGKSTITVGLGDALNKINKKSVIALREPSLGPVM
                     GIKGGAAGGGYAQVLPMEDINLHFTGDMHAITTANNALSALLDNHIHQGNELNIDARR
                     VIWKRVVDLNDRELRKVIVGLGGPIQGVPREDGFDITVASEIMAILCLAADLEDLKAR
                     LARIVVGYTFDRQPVTAGDLKAEGALALLLKDAIKPNLVQTIYGTPAFVHGGPFANIA
                     HGCNSILATKTALRLADYVVTEAGFGADLGGEKFLDIKVPNLKKAPDAVVIVATVRAL
                     KMHGGMKKDELKNENLDALKVGFANLKRHIRNMEQYQLPVIVAINEFVTDTDNELTLL
                     EHLCENQGILAKRASVWADGAEGGVDLAKAVVRLIDRKEANYKPLYRLEETIQEKTET
                     IVKKIYGGNGVVFSKKAQKQIEEFTKNGWDKLPICMAKTQYSFSDDPSLLGAPEDFTI
                     TIREIIPKLGAGFLVALTGDVMTMPGLPKKPAALNMDVTNDGEVLGLF"
     gene            33856..34242
                     /locus_tag="LLC22_000340"
     CDS             33856..34242
                     /locus_tag="LLC22_000340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433647.1"
                     /translation="MKTTFIRKTGFYGMGSSIQLRINNEKRSVLSHEQKITLDLEVPF
                     TMQVTFYWLKSPVYTVKEAKPAYVITMNYLILQIYPFLFLATGLGAVFLQNLFFSFFA
                     VIVLIAFFFYIKNRAYLIKEENYGKL"
     gene            34229..34927
                     /locus_tag="LLC22_000341"
     CDS             34229..34927
                     /locus_tag="LLC22_000341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5433648.1"
                     /translation="MANSDLFLISFNRIEKWMRDEMGNARNMGFTELVRRLAQRKQLM
                     IRKYEDDLLQLAQLRNAIVHDRIAVDFVIAEPNDWTVKRIQLIEQELIQPETVLPRFA
                     KRVTGFEQDLPLLELLKIVAEKRYSQFPLYNKGKFVALITLRNIGFWLAKESQKGPVD
                     LTNKRALDLIIQNGKYTNYHFVPAKTHIYEVEAMFREQGTLEAVLITKDGNPDGNLLG
                     IVRPRDIYKQIEKD"
     gene            34932..35396
                     /locus_tag="LLC22_000342"
     CDS             34932..35396
                     /locus_tag="LLC22_000342"
                     /EC_number="3.4.23.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase II"
                     /protein_id="HBK5433649.1"
                     /translation="MLIIYWIFSALLVGVDQLVKWWITDNLALGETKNLIPGILSLNH
                     IRNTGAAWSMLEGKMWFFTIVTLIAVVVILTLMIKNREKGNRWFMIGLSLILAGAIGN
                     FIDRIRLGYVVDMFQTDFMSFPIFNVADVTLVCGVICMLIYIILDEKDQRKK"
     gene            35393..36304
                     /locus_tag="LLC22_000343"
     CDS             35393..36304
                     /locus_tag="LLC22_000343"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK5433650.1"
                     /translation="MTELKTTIHHESGRIDKVLTNLFTDYSRSQIQLWLKNGAVSVNG
                     QPVKANYKVKQGDEITVLIPEPETLDVVPENIPLTIVYEDEDVAVINKPQGMVVHPSA
                     GHTHGTMVNALMYHIKDLSTINGVIRPGIVHRIDKDTSGLLMVAKNDQAHESLAQQLK
                     DKTSLRKYVALVHGEIPHEKGTINAPIGRSKENRKMQAIREDGKSAVTHFTVLERFEG
                     FTLVELKLETGRTHQIRVHMKYIGYPLAGDPVYGPKKTLKGNGQFLHAQMLGFTHPTT
                     NEKMIFEAPLPEVFEKTLEKLRKNIAF"
     gene            36539..37078
                     /gene="pyrR"
                     /locus_tag="LLC22_000344"
     CDS             36539..37078
                     /gene="pyrR"
                     /locus_tag="LLC22_000344"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional pyr operon transcriptional
                     regulator/uracil phosphoribosyltransferase PyrR"
                     /protein_id="HBK5433651.1"
                     /translation="MQAKEVVDQVTMKRALTRITYEIIERNHSIQDIVLVGIKTRGIY
                     IASRIAERLKQLEDIDIPVGELDITLYRDDKKENPEEPELHSSDIPVSLEGKEVILID
                     DVLYTGRTIRAAMDAVMDFGRPRKISLAVLVDRGHRELPIRADYVGKNIPTSRAEEIL
                     VEMQELDGQDRIMILKEED"
     gene            37092..38375
                     /locus_tag="LLC22_000345"
     CDS             37092..38375
                     /locus_tag="LLC22_000345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil permease"
                     /protein_id="HBK5433652.1"
                     /translation="MSEKKGFHNDDVVLDIHDRPTPGHWVGLSLQHLFTMFGATVLVP
                     ILVGIDPGIALVSSGLGTLVYLFTTKGKIPAYLGSSFAFIAAMQLLMKTDGYPAIAQG
                     AVTTGLVYLIVALIIKKIGSAWLDKILPPIVVGPVIMVIGLGLAANAATNAMYNQGTY
                     DFKYIAVALITLGLTIFFNMWLRGFLGLIPILLGIISGYIVALLFGIVDTKPIVDAAW
                     FAVPNFEIPFVQYEPKLYLGAITTMAPIAFVTMTEHIGHLMVLNKLTKRNFFEEPGLH
                     KTLTGDGLAQIVAAFVGGPPVTSYGENIGVLAITRVHSVFVIGGAAVFAVILGFVGKL
                     SALILSIPGPVISGISFILFGVIAASGMKILIENKIDFDKKKNLLIASVILVVGIGGL
                     VFEVGTFTLSAMALATVLGIILNLILPETSRSEEN"
     gene            38388..39314
                     /locus_tag="LLC22_000346"
     CDS             38388..39314
                     /locus_tag="LLC22_000346"
                     /EC_number="2.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322463.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate carbamoyltransferase catalytic
                     subunit"
                     /protein_id="HBK5433653.1"
                     /translation="MIIKSERISLKHLLTVEALTDQEVMGLIRRGQEFKQGANWTPQK
                     RQYFATNLFFENSTRTHKSFDVAEKKLGLEVIEFEASTSSVQKGETLYDTVLTMSALG
                     VDVAVIRHGDENYYDELIQSKTIQCSIINGGDGSGQHPTQCLLDLMTIYEEFGHFEGL
                     KVAIVGDITHSRVAKSNMQMLKRLGAQVFFSGPREWYDDEFEVYGHYMPLDELLDQVD
                     VMMMLRVQHERHDGKESFSKEGYHQEHGLTVERAKKLQKHAIIMHPAPVNRDVELADS
                     LVEGLQSRIVQQMSNGVFVRMAILEAVLNGKA"
     gene            39333..40613
                     /locus_tag="LLC22_000347"
     CDS             39333..40613
                     /locus_tag="LLC22_000347"
                     /EC_number="3.5.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotase"
                     /protein_id="HBK5433654.1"
                     /translation="MKTLIKNGQINTRKNMTTPAEIWIEDGRIKAIGTGFSEAEFDEV
                     FDAKGQLITPGLVDVHVHLREPGFTYKETIEAGTRSAARGGFTTVCAMPNLNPVPDTA
                     EKLRQVYDIIRKDAVVKVLQYAPITENLRSEKLVDQEALIEEGAFAFTNDGVGVQTAG
                     TMYLAMKEAAKNNKALVAHTEDESLLFGGVMHAGKKAEELGLPGILSVTESSQIARDL
                     LLAEATGVHYHVCHVSTKESVRVIRDAKKAGIHVTAEVSPHHLILIDEDIPEDFGFWK
                     MNPPLRGREDREALIEGLLDGTIDCIATDHAPHGLEEKSQSFMKSPFGIVGSETAFQL
                     IYTHFVETGRFTLEQVINWLAVKPAEIFGLNAGTLTVGAPADVAVFDITQTCTIDKED
                     FLSKGENTPFIGWKVKGETQMTFVNGKLVWQKGE"
     gene            40618..41694
                     /gene="carA"
                     /locus_tag="LLC22_000348"
     CDS             40618..41694
                     /gene="carA"
                     /locus_tag="LLC22_000348"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine-hydrolyzing carbamoyl-phosphate
                     synthase small subunit"
                     /protein_id="HBK5433655.1"
                     /translation="MERLLILEDGTVFEGKAFGADASVFGEIVFTTSMTGYQETITDQ
                     SFNGQIITFTYPMVGNYGVNRDDYESISPTCKGVVVKEHARVASNWRNQMTLDSFLKQ
                     KGIPGISGIDTRALTRKIREVGTMKASIVDAGDSFEHAFDQLKATVLATNQVQQVSTN
                     KPYPSPGTGRKVIVIDFGLKHSILRELSKRNCNLTVLPYNTDAETILALSPDGVMLTN
                     GPGDPKDVPEAIEMIKKIQGKVPIFGICLGHQLFALANGADTYKMKFGHRGLNHPVRE
                     VATGRIDFTSQNHGYAVDEATIDPEKLIVTHVEVNDGTVEGVKHRDYPAFSVQFHPDA
                     APGPHDALHLFDEFMEMMDAGKEQ"
     gene            41699..44884
                     /gene="carB"
                     /locus_tag="LLC22_000349"
     CDS             41699..44884
                     /gene="carB"
                     /locus_tag="LLC22_000349"
                     /EC_number="6.3.5.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001126118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamoyl-phosphate synthase large subunit"
                     /protein_id="HBK5433656.1"
                     /translation="MPKRTDIKKIMVIGSGPIIIGQAAEFDYAGTQACLALKEEGYEV
                     VLVNSNPATIMTDKEVADQVYIEPITLEFVSRILRKERPDALLPTLGGQTGLNMAMEL
                     AASGILEELNIELLGTKLSAIDQAEDRDLFKQLMKELNQPIPESEIVNTVEEAVDFAN
                     KIGYPVIVRPAFTLGGTGGGMCENEEELRIVSENGLSLSPATQCLIERSIAGFKEIEY
                     EVMRDSADNAIVVCNMENFDPVGIHTGDSIVFAPSQTLSDHEYQMLRDASLSIIRALK
                     IEGGCNVQLALDPHSFNYYVIEVNPRVSRSSALASKATGYPIAKLAAKIALGLTLDEM
                     KNPVTGTTFAEFEPALDYVVAKIPRWPFDKFENGERLLGTQMKATGEVMAIGRNIEES
                     LLKAVRSLEIGTHHIELPELADITDDDLIQKVVRAQDDRLFYVAEAIRRGYTIEELAD
                     LTKIDLFFLDKLLHIVEIEQQLKQQPLDDKILKTAKQNGFTDKKVAELWEINEEAVRQ
                     MRKENDLIPVYKMVDTCAAEFESKTPYFYSSYEYENESSRSEKPSILVLGSGPIRIGQ
                     GVEFDYATVHSVKAIQQAGYEAIIMNSNPETVSTDFSISDKLYFEPLTFEDVMNVIEL
                     EQPIGVIVQFGGQTAINLAEPLTAAGVKILGTTIEDLDRAENRDLFEQALKELDIPQP
                     LGDTATSKEEAVVIASRIGYPVLVRPSYVLGGRAMEIVENQRDLEDYMEHAVKASPEH
                     PVLVDRYLLGGECEVDAICDGETVLIPGIMEHIERAGVHSGDSMAVYPPQTLSESIKK
                     TIEDYTIRLALGLNCVGMMNIQFVIHENEVYVIEVNPRASRTVPFLSKVTGIPMAQIA
                     TKAILGEKLKTLGYENGLYPETKEVHVKAPVFSFTKLQKVDTYLGPEMKSTGEVMGSD
                     RQLDKALYKAFEASGLHLPEYGAVLFTIADETKEEALELAKRFTEIGYSLIGTKHTAA
                     YFEKNGLVVETVAKISEEAAEKNVVDLIRDGKTQVVVNTIDKDRGNASKDGFIIRREA
                     VEHGIPLFTSLDTADAIVRVMESRAFSTNPI"
     gene            44938..45714
                     /locus_tag="LLC22_000350"
     CDS             44938..45714
                     /locus_tag="LLC22_000350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase electron transfer
                     subunit"
                     /protein_id="HBK5433657.1"
                     /translation="MKQEMMEIVQQKQLAPKIFEMTLKGDLVKEMQQPGQFLHILVPR
                     ADLLLRRPISLNHIDHETNTCRIIYRVEGEGTRVFSTLSAGDHLDVMGPLGNGFDLSN
                     LHTGDEVFIIGGGIGVPPLYELSKQLVEKGIKPTHFLGFATHEVVYYEKEFNRLGETR
                     IATDDGTYGMHGNVGNLLLGTKTEPTAVFACGSNGLLKTVEQLFSSHQNVQLSLESRM
                     ACGIGACYACVCHTPEDETGTKSVKVCDEGPIFKIGEVII"
     gene            45711..46643
                     /locus_tag="LLC22_000351"
     CDS             45711..46643
                     /locus_tag="LLC22_000351"
                     /EC_number="1.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate dehydrogenase"
                     /protein_id="HBK5433658.1"
                     /translation="MNENPLAVKLPGLELKNPIMPASGCFGFGKEYGKYYDLNQLGSI
                     MVKATTPNARFGNPTPRVAETPSGMLNAIGLQNPGLDVVMHKLLPELEEYNELPIIAN
                     VAGACEEDYVEVCSKIGEAPNVKAIELNISCPNVKHGGIAFGTDSDVAFQLTQAVKKV
                     SSVPVYVKLSPNVTDIVPIAQAIEAGGADGFTMINTLLGMRIDLKTRKPILANQTGGL
                     SGPAIKPVAIRLIHQVASISSLPIIGMGGVQTVDDVLEMFMAGASAVAIGTANFTDPY
                     ICPKLIKELPVRMSELGIESLERLIKEVREERER"
     gene            46640..47356
                     /gene="pyrF"
                     /locus_tag="LLC22_000352"
     CDS             46640..47356
                     /gene="pyrF"
                     /locus_tag="LLC22_000352"
                     /EC_number="4.1.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotidine-5'-phosphate decarboxylase"
                     /protein_id="HBK5433659.1"
                     /translation="MNQLDQRPIIALDFSTRQEVEDFLRFFPKEEKLFVKIGMELFYQ
                     EGPEIVRYLKEAGHNVFLDLKLHDIPNTVEKAMRGLAKLGVDLTCVHAAGGIRMMEAA
                     MRGLEEGTPEGGKRPLLLAITQLTSTSEEEMHADQLIEVSLEKSVIHYASCAKKAGLD
                     GVVSSAWEVEAIKEMAGDEFVCLTPGIRPEGTVAGDQTRVVTPSQAKKIGSTFIVIGR
                     PITQSTNPYKAYQTIQTEWS"
     gene            47363..47992
                     /locus_tag="LLC22_000353"
     CDS             47363..47992
                     /locus_tag="LLC22_000353"
                     /EC_number="2.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288884.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="orotate phosphoribosyltransferase"
                     /protein_id="HBK5433660.1"
                     /translation="MNVEQSIAKDLLEIEAVFLNPSNPFTWASGIKSPIYCDNRITMS
                     YPKVRKEIAKGLASKIKEAYPEVQVIAGTATAGIPHAAWVAEILDLPMVYIRSKAKDH
                     GKGNQIEGRIFEGQKMVVIEDLISTGGSVLEAAEAAKREGADILGVAAIFTYELPKGK
                     ANFEKAEIPLMTLTNYSVLIEAALEDRYIDEQELTLLKEWKKDPENWQI"
     gene            47980..48294
                     /locus_tag="LLC22_000354"
     CDS             47980..48294
                     /locus_tag="LLC22_000354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433661.1"
                     /translation="MADLSALDEDREIRFVSPESSIGIAKIQKLIARSIFSSGMKRNF
                     YRDQFLIFLKFIFLRLVSRKKRIISSLFSIIYRFSLFFGKGAVSKMVKSGNVANISYL
                     MI"
     gene            48332..48973
                     /locus_tag="LLC22_000355"
     CDS             48332..48973
                     /locus_tag="LLC22_000355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5433662.1"
                     /translation="MGLNEFILGLNNLETITRAPGFFKYTEHTVAAHSYRVASIAQVL
                     GDIEEANGQPIDWKLLYEKSLNHDYTERFIGDIKTPVKYASKELRGMLQTVEEKMTDE
                     FINQEIPAEFQEVYRRRLFEGKDETVEGELLAISDKVDLLYESFDEIIKNNPEKVYKE
                     MFIEAVTTIKSFEHRPSVQYFFKEIFPELLNQEFYGKEAFLETVSTIVKKEEK"
     gene            49016..49708
                     /locus_tag="LLC22_000356"
     CDS             49016..49708
                     /locus_tag="LLC22_000356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376854.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbonic anhydrase family protein"
                     /protein_id="HBK5433663.1"
                     /translation="MDVEWGYSGDKGPENWASLCDWFARGAEFPLQSPIHLTKGEETK
                     IEGDTLSFHYQKQRFTDKEFKNTIHLVPFDQLSYVEFKKERYYLTDIHFHLPSEHIIN
                     GKQEDIEFHFVHMNSKKENLVVGVMYQLMVQEGWLYNQENGESWNLEKHEHWVNPDVF
                     FPEQKSHFHYIGSLTTPPTSGPIQWFVMDHVGKLNQEFLLPFDGQYARPNNRPIQPLN
                     GREIYYFEEFEQ"
     gene            49705..50607
                     /locus_tag="LLC22_000357"
     CDS             49705..50607
                     /locus_tag="LLC22_000357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5433664.1"
                     /translation="MNIQQMKYVVAVANNGSFREAAKKMFVSQPSLSAGIKELETELG
                     ITLFTRTNRGAYLTEEGQDFLNRAEKILVQLDTLETHYLTSEKRDNFSIAAQHYDFLG
                     PLTAQLLEEFKDEIKQFRIMETTTARVIEEVKEQHSEIGIIYMNEHNQAGIRRYLQQG
                     ELSGRSIGKFKTHIFLRQGHPLAEHAEITKEELLSYPQVRFTQDGNNFPYFYEDLIEI
                     PDQETVIYTSDRGTLMNIVLETDAYASGSGIVIGGIREHLRLIPLAEGELNEFYIIYS
                     AKRPLSEIAQRFIKELTRLLDQQS"
     gene            complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="LLC22_000358"
     CDS             complement(50765..52471)
                     /gene="efbA"
                     /locus_tag="LLC22_000358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibronectin-binding protein EfbA"
                     /protein_id="HBK5433665.1"
                     /translation="MSFDGVFTHAMVNELRETLLSGRISKIHQPYENEIVLVIRSRGK
                     NHRLLLSAHPSYARVQITQIDYQNPDNPPNFVMMLRKYLDGAILEDIEQIENDRVIHF
                     HFAKRNELGDLQNIILIVELMGRHSTIVLVNRETGKILDAIKHIGSSQNTYRSLLPGV
                     EYVAPPKQEVLNPFSSEKEKIFQRLSQTELDPKAIQRQFQGIGFDIAQELTKRLLERP
                     NEKMVVWDEFFSAISHQPIPTFYETENKDFFTPIAYQVLSEQASAVTAYPTLSQLLDS
                     YYHEKAEKDRAKQQGGELIRKIENELKRNKNKLKKREQTLKESENAENYRRNGELLTT
                     FLTQVPRGAKEVVLPNYYEEDRPIKIALDPALTPNQNAQKYFHRYQKLKNAVKLIGEQ
                     IQEAKDEIQYLESVLSQLEIAGPMDIEAIKEELTSEGYLKKKNLKKQKRKKPSQPDQY
                     FSSDGTLILVGKNNLQNDQLTMKTAKKTDYWLHAKNIPGSHVIIKSDKPSDETITEAA
                     ELAAYFSKYRYSAQVPVDLVQVKHIRKPNGAKPGYVIYENQKTIIVTPEEEKITAMKQ
                     NR"
     gene            52661..53284
                     /locus_tag="LLC22_000359"
     CDS             52661..53284
                     /locus_tag="LLC22_000359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433666.1"
                     /translation="MFVIWEVVKSRVQEMNEHFSVSFAENPSKYFRRLVFLLILSLLL
                     TVAMFLLPEKIREEQVNSLVYSSIPTSKLKPFDYSKADQKIKQSRAISVMFSKPNGKT
                     YQDMLDVFNDPELMEELNRPIFYYPIVYDVHELEQKYNIRTDEVTFIFFDGGKEANRI
                     TAGKGGITDFDKELIPELNRLPLANIKQLEEELDRTGVTSQNSEIAN"
     gene            53734..54783
                     /locus_tag="LLC22_000360"
     CDS             53734..54783
                     /locus_tag="LLC22_000360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5433667.1"
                     /translation="MKNKRLITVVVIILVYLAGAFIYGKASGEKESTSTNQTKKTTVV
                     GVLQYVSHPALDEIYRGIKDGLKEEGLKEGENLEIKFQNGQADQSKLATMSQQLVQSD
                     PDALIGIATPAAQSLANTTSSIPVVLGAVTDPVGAGLVASLEKPGGNVTGVSDQPPVT
                     SQIKLASDLLPNAKKVGILYASSEDNSKYQVAQAEEAAKKEGLESVKYAVPSTNEIAQ
                     TVQVMSRQVDFIYVPLDNTIANAMQTVVKEANKANIPVIPSVDTMVEQGGLATIGINQ
                     YQLGLQSGKMAAELASGKEKPETTPVYTFDQGDTVINQSQADRLGIIVPQSMKEKAKI
                     ITDDSQQETSKEDDK"
     gene            54780..55661
                     /locus_tag="LLC22_000361"
     CDS             54780..55661
                     /locus_tag="LLC22_000361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5433668.1"
                     /translation="MIVSAISQGMLWAILGLGIFMTYRILDFPDMTTEGSFPLGAAVC
                     VTAITHGVAPIVATLLGVGAGMIAGLVTGLLYTKGKIPVILAGILVMSGLNSVILFVM
                     RTPNLSLLNHPILQDSFHRFGLPDYFDTVLLGFISLGILIAVLLFFFNTDLGQGYIAT
                     GDNETMARSLGIKTDRMKILGLTLSNGVIALSGALIAQNDGYADVNKGIGVIVIGLAS
                     IIIGEVIFQELTLAERLIAIVVGSIIYQLLILVVIKLGFDTTYLKLFSAIILAICLMI
                     PQLKKALNLKTGFEKEA"
     gene            55664..56434
                     /locus_tag="LLC22_000362"
     CDS             55664..56434
                     /locus_tag="LLC22_000362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5433669.1"
                     /translation="MTDILTIKNGRKVVNNGMNEEKVLLDEINLTIREGDFITVLGGN
                     GAGKSTLFNTIAGTLQLSQGSISFKDQLITKDSEEKRARFLSRVFQDPKMGTAPRMTV
                     AENLLLAQKRGQKRKFRLRNLKNQKEDFFRLCQEVGNGLEQHLDTPAGELSGGQRQAL
                     SLLMATITAPELLLLDEHTAALDPKTAKALMRLTNQRINEQKLTCLMITHRMEDALKY
                     GNRLIVLQKGKIVQDISEKEKQHLTMGDLLQFFEEVVD"
     gene            56713..57567
                     /gene="aroE"
                     /locus_tag="LLC22_000363"
     CDS             56713..57567
                     /gene="aroE"
                     /locus_tag="LLC22_000363"
                     /EC_number="1.1.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate dehydrogenase"
                     /protein_id="HBK5433670.1"
                     /translation="MISGQTKLAGLFADPASHSLSPLMHNTAFEANNIDAVYLAFQVN
                     PMNLKQAVESIRTFDMLGVNLSMPNKTAVIPYLDEVSQEAQLIGAVNTIVHEKGRLIG
                     YNTDGAGFMQSVQEAGISIKKKKMTLLGAGGAAKAVTVQAALDGAEEIVVYKRNNQTF
                     AQVKETFEQLSYRTSCKIKVRDFADTHQLRKDLKESCLLVNATDIGMGKKINQSPLLD
                     ISMMHENLAVFDLIYAPRETRLLKEAKKVGAKGYNGLGMLIYQGAIAFELWTKEKMPI
                     HVIEKLFD"
     gene            57745..58908
                     /locus_tag="LLC22_000364"
     CDS             57745..58908
                     /locus_tag="LLC22_000364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5433671.1"
                     /translation="MSRMDRYKDIHKKAKPLKRDTGSIFARRERKRTRMENEEDATRI
                     YEREQHSFEHLNQYEQQIYRDAPRAEEQQKNKKFFNRQKKNKPLKPRRKRSWKKIILS
                     ILLVLILYSGISFFIGKYVAEHDTSLEAATSETFHGQKATNGAHNILILGSDTRGEDA
                     GRADTIMVLQLDGPSHKPKLISFMRDSFVTIPGVGQNKINSAYAYGGADLVRQTLVEN
                     FGIDCQYYAKVDFKSFEKVIDALFMNGVKIDAEKDLNLDGVDIKKGGQKMDGHVLLQY
                     ARFRMDEQGDFGRVRRQQQVMNAIFSQLKNPLNLIRAPYAAGKALGYTSTDVTAWFLT
                     KNLFSIARGAGGIDRISVPVDGSWNYGQSDYAGSILEIDNQMNQSAITDFLNK"
     gene            59025..59435
                     /locus_tag="LLC22_000365"
     CDS             59025..59435
                     /locus_tag="LLC22_000365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5433672.1"
                     /translation="MDIYLNFKNESREAIAFYEKVFQTEASGITTYGEMPGIEQMNLP
                     EEAKNLITNARLNIYDTLVMFADTPEGIGPELVVGNNVSLVIQTRNEEETKRLFESLA
                     EGGKIEMPLDAVPWAQLYGMVTDRFGINWQINQE"
     gene            59609..61837
                     /gene="topB"
                     /locus_tag="LLC22_000366"
     CDS             59609..61837
                     /gene="topB"
                     /locus_tag="LLC22_000366"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK5433673.1"
                     /translation="MKTVILAEKPSQAKAYAETFQQQKRHEGYYEISDPLFAGEVTIT
                     YGFGNLVDMVAPGAYEERWAKWSLENLPIFPETFRYEVPMDKRAQFSIVKRELQSADT
                     IIIATDGDREGEAIAWSIIRQANAFSKEKNYLRLWINSLEKEAIYEGFKNLQPGKNYF
                     PKYKEAQARQNADWLIGMNGSPLYSLLLQRKGIDGSFSLGRVQTPTLYMIYQLQEEIK
                     HFKKETYFEGEGLITTNKGQFSGKIVPKKAFKTQEELTKEIEKLGAHLGKQNGRILEV
                     TKKEKRLHSPRLFSLSSLQTKMNQLMKASAKATLDAAQGLYESKFLSYPRTDSFYITE
                     NEHQYLVKHLQNYKKFLGIEEVQTTEIKAKKRYVDAKKVQEHHAIIPTKTIPTPARFA
                     KLSKLQQAIYLQVLRTTVAMFAADYIYEETTVMTGVQQLKLKSIGKIPLQQGWQEILR
                     IKSKKKEAQTLPPIVENEEAEVELKSMEKETQPPKPYTEGTLITAMKTAGKTLDNDEA
                     QEILKEVEGIGTEATRANIIENLKQKHYIEVNKNEITVTPKGITLCKAVANEPLLTSA
                     EMTARWEGYLRKIGKQEGTPSVFLENIKKFILHLLAEVPNQIDKVDFSDEISGTRQIK
                     AMEKKNDQLGRCPKCKKGIVMLYPKIATCLNPECDFKLWPTVAKKKLTKTNLRDLLSK
                     GKTSKVVKGFTGKKGKFDAVLVLKEDMTIGFSFPWIENSGTKAVDGNKETSRKNNENE
                     VE"
     gene            62008..62292
                     /locus_tag="LLC22_000367"
     CDS             62008..62292
                     /locus_tag="LLC22_000367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433674.1"
                     /translation="MGAITIVAVYQAFLKYPDYGTKLLSLTHNQTAYSPTLILSTLTA
                     GAKSATYFFHKTTSMLKRKKQRKQLLVVVAAMIIIYFLPVITQVFHQYFG"
     gene            62452..62688
                     /locus_tag="LLC22_000368"
     CDS             62452..62688
                     /locus_tag="LLC22_000368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5433675.1"
                     /translation="MKKMKKYKIRKSGNSDVTTIPPEVKEFMGVQTGDAISYVFQSDG
                     SVRMIKAQEEPDIDSLVDSIMNQYEDALKDLVDL"
     gene            62685..63083
                     /locus_tag="LLC22_000369"
     CDS             62685..63083
                     /locus_tag="LLC22_000369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system death-on-curing
                     family toxin"
                     /protein_id="HBK5433676.1"
                     /translation="MRYLSTKEIIKINAKVILRHSPGEMIGVKDANALDMAVKQPSQA
                     VFNQELYPEIYEKAAILAINLAKKHPFHNGNKRTALVAMLLFLQLNNCPVAFSRQEAV
                     DFIIMITTSSLDFDSLKSKITSYLRQTAIK"
     gene            complement(63750..64694)
                     /locus_tag="LLC22_000370"
     CDS             complement(63750..64694)
                     /locus_tag="LLC22_000370"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBK5433677.1"
                     /translation="MKKTSRKVVIVGTGFVGTSIAYAMINQGISNELVLIDVNQEKAE
                     GEALDLLDGMAWGDENVAVWSGGYEECKDADIVVITAGINQKPGQSRLDLVKTNASIM
                     RQIVKEIMGSGFDGIIVVASNPVDILTYIAWNESGLPTSRVIGTGTTLDTTRFRKEIA
                     LKLKVDPRSVHGYILGEHGDSEVAAWSHTTVGGKPVFEIVEKDHRIAQDELDVIADKV
                     RNAAYEIIDRKKATYYGIGMSTARIVKAILNNEQAVLPVSAYLTGEYDEKDIFTGVPS
                     IVDENGVREVVELSINEEEKAMFSKSTSALREVLNTVL"
     gene            complement(64990..65934)
                     /locus_tag="LLC22_000371"
     CDS             complement(64990..65934)
                     /locus_tag="LLC22_000371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433678.1"
                     /translation="MRNEESIETLQREQGMNINDLNLAYHLQTPPKIHRGDLFQQGNI
                     HISKHRRYAEVPEHTHDFVEINYMYSGTCLQIINGERIEMEESDVVIIDKEATQRIEY
                     TGQEDILINILLKEETLSTEILNHLASTNNLLSSFLINASKEKGEHTQFIHFRGGKTS
                     RLTHLIENMLLIYFDTYSHKIRSLNLYTSLLLIELTHLLEQQSFSSADGCAENEMLRV
                     LDYIDKHFTSCTLKETAAHFGYNPVYLSNKLKMYFDASFQELVLKKKFDFALELIQET
                     SFSLEEIANRIGYKQTTSLFKLFKKYSTCTPNEWRNKH"
     gene            66155..67369
                     /locus_tag="LLC22_000372"
     CDS             66155..67369
                     /locus_tag="LLC22_000372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5433679.1"
                     /translation="MLMNKKMMKFSLLSVSLILTSAGAVTSAIPSMSATYATRSLSAV
                     ELLTTAPSFMVTIFVLISSFIARKIGQKQTVIIGLVIASICGILPLFSQSYSIVLASR
                     AGLGIGFGLINSLAVSMIAAFYHGDERASMIGFQSAFQGFGAALMTFVAGQLVQFGWQ
                     YTFLVYAISLPILVLFVLFVPTPETTELQSHGTAPTRQVIKTNPKMISYGIFLLLVIV
                     VYNAVSIKLATVLTTYSLGNETNAANILTIMQLASMAAGVCFGWLQTKAHRYMLTLSL
                     LLMGIGFVLIATVINLYVIGFGAILTGISFSLFIPYLFNQVSIQAPKYAESFNTSILL
                     VGANLGTFIAPYGLLFLSFASLGSKTLAVFVNGSILLLISALISLLVVHRTNRKTVIR
                     VDEEIKEQLTTK"
     gene            67391..69406
                     /locus_tag="LLC22_000373"
     CDS             67391..69406
                     /locus_tag="LLC22_000373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 78 glycoside hydrolase catalytic domain"
                     /protein_id="HBK5433680.1"
                     /translation="MTNEKHKDRWLWYPGDFEIRHGLLQNFQREERGFDWPAYWYMDD
                     CHRNVKFKRYYFLDQPSMFKVTIQGVGYVEINGQKHPCGKWLTCPAGKAKIRIFVGHT
                     SGLPAMFIEGDEVKSDIGWTASNFIEEYPAGWSPLYVDIAKDPNQIYYQKECVHPVTE
                     TEIGGGILFDFGRAVNGCVELISLDDHIESITLCYGESDVEAMDIDYCYYKQIGMTRK
                     MKARKRAFRYLFIPEVSTGMVQLQVFHEFLSLSKQAAFSSDSSLLNQIWSVSEEAFKL
                     CSDLFFIDGIKRDRWIWSGDAYQSFMINQYLFFDEEINKRTILALRGQNEIKQHMNTI
                     VDYSILWLIGIENHYMMTKDYEFLRIVYPKMQSLMRYLMEQTNELGFIYGRAKDWIFI
                     DWSEMDKEGTLAAEQVLLLKAYHSMITCGDILAETYGENENYHTHLYQEKYQLLKQNL
                     FDYFWDEELGAFIDCYESGRRNVTRHANIFAVLFDFANKDQQQSILKNVLLNDTITQI
                     TTPYFKFYEQDALCKLGQTNIVYQTILDYWGGMLSHDAVTFWEEYDPTQTGNEKYSMY
                     GDPYGKSLCHAWGASPIYLLGRYFIGLYPTKPGYEEFMIQPNLDSFETLNCTLPIKDG
                     KISLEKTKDKIVITSDRTGGTVKMNGKSYPLLAKQPLVLTSYSKINA"
     gene            complement(69489..70862)
                     /locus_tag="LLC22_000374"
     CDS             complement(69489..70862)
                     /locus_tag="LLC22_000374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBK5433681.1"
                     /translation="MDKLLNLFVSIVSQPSILVSLIALLGLVLQKKKFSEVIQGTIKT
                     FVGFLVLIGGAGLISNSLTPFASMFQTALHTQGVVPSNEAVVAIALQQYGTPTALIML
                     VGMIVNILLARFTRYKFIFLTGQAMLYVSCLTAVILVSAGFTANLWMILLGGVFEGTL
                     LTITPALCQPFMKNITGNNQVALGHTGNIGYASSGWIGKFFGNKDRSTEDIKIPKSFS
                     FLRDSTVSIMLLMSIVYVALALLAGPGFVERELSNGDNAVIFALIQAGTFTAGFVIVL
                     QGVRMVLAEIVPAFQGIAKKLVPDSKPALDVPIVFPYAPNAVLIGFFVSFFVGTLSMF
                     AMIGLQTTVIIPGVVGHFFCGAASGVFGNSTGGRRGAVLGSAFNSLLISWLPLFILPV
                     LGDLKIASSTFADTDYLVPGLVLGKLGEYGQIALTVGIIAFFLLVVLSSFLFAGKRTN
                     IVSKEQN"
     gene            complement(70888..71172)
                     /locus_tag="LLC22_000375"
     CDS             complement(70888..71172)
                     /locus_tag="LLC22_000375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5433682.1"
                     /translation="MKIFAVCQSGLGTSFMVEMNIKQALADLGADVDEFEVSHTDVGS
                     VSSDMADYFFIEHSLKDTLTSIPDEKLVPLQSIIDSEEVKEKVTKILSKE"
     gene            complement(71174..73189)
                     /locus_tag="LLC22_000376"
     CDS             complement(71174..73189)
                     /locus_tag="LLC22_000376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5433683.1"
                     /translation="MNYKISYLLKTPREISLEKAAEIIEVNTSEAIKQLTPFAEYVDD
                     TRIRIKKFRAIDWAEKFLDITRFEAVYTEQERRDLLYLMVYSTATSVSVFHFQDFLQV
                     SKGTVLSDIKKIRNELEVEDCQLSYTRKTGFRLLGSEAILRREAKNRTARLMQSLAGR
                     FGLTYLTATLSIDYYAKVRDLLDKTISLSDLRFAPNRMDELAYYLSLTTIRIGKTSME
                     LVKDAELLASLAVTDISRQVLTGLGYSEHQNSEIIFFSLCLASIVEGDVQEPALDFLL
                     ECSSEVIHRMEFLMAVEFASFRELLMNVFYHLVPAYFRISYSFYLPNVMIDQIKHQYA
                     SIYEMTRKALLPLERRIGKSIPEEEIGFFTILFGGEIRKADAEERNRKIRAVIVCPSG
                     ISSSLILKSELQQLFPMIFFTETNSADRLHEVDETSYDIIFSTVPLTLTDKKKSLYVL
                     HPIMTDLEKNQLINQVQRDWLIPGFSMPSAQELLSALLPYIELKEGVDEEKLYQVLNR
                     KMNKLLEKKEDQRPMLSELLTEEMIQLSDQPKNWQEAITFAAQPLLSENKIEESYIKA
                     MIERVEQYGAFIHIGDHIALPHARPEDGVNEVGMSLLKLQQPVDLLDNPAHPISLFIC
                     LAAIDNEAHLRALANLTKLLSNKQNLQDLLHASTKEEILAIIRKGDE"
     gene            complement(73368..73673)
                     /locus_tag="LLC22_000377"
     CDS             complement(73368..73673)
                     /locus_tag="LLC22_000377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA processing protein"
                     /protein_id="HBK5433684.1"
                     /translation="MTNYDGEKHKRLRGSMAPKTEEEVALAGTNSGETEDKEESLAGT
                     NSGETENKETALSGSNSVEEETKPNEPNHFEKDIEKAVEDVKEKFEELTSKNKHDHH"
     gene            complement(73762..74793)
                     /locus_tag="LLC22_000378"
     CDS             complement(73762..74793)
                     /locus_tag="LLC22_000378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306737.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5433685.1"
                     /translation="MLTIAYLGNGKSTNRYHLPFSRKLTNKINIKKIFSPSEPVWKTF
                     EDIEYTDQLSDLWDDPEIQLVVITTPSQFHYEYGKMALEHGKNVLVEKPFAETSKEAE
                     ELFALAKEKGLFIQCYQNRRFDSDFLTVQKVIESGKLGDILEVEMHYDYFRPEVPENT
                     HEFSTANSYLYGHACHTVDQVLSYFGEPDDISYDVRQLLGKGRMNDYFDLDFFYGNMK
                     ISIKSSYFRIKERPSFVVYGKKGMFVKQTKDRQEEHLKMFYMPDHEDFGIDLPEHYGV
                     LTYIDEQGSYHEEKVISEVGDYSRVYEGIYETLVNGAEKVIKDEETILQMKILEEGIK
                     SIQESEGKI"
     gene            75000..75875
                     /locus_tag="LLC22_000379"
     CDS             75000..75875
                     /locus_tag="LLC22_000379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5433686.1"
                     /translation="MLIEEKLTKQELFTTTEKRIVDYIRRNIEAAVYMTIEELAKATY
                     TSHSAIIRLCKKMGFSGFKEFRFELGREVHQLIAQFNQTIDPNFPFSSEDSTQQIAKK
                     MADLSIQSIKKAQLQIEHEDLDQIGKVLNKAQRIFLFAKGDSQITARKFQNKMVKLNK
                     FLIMAEEYSDSSWNAANLTSEDCAIFISYSGRIHHYERIMTYLKHVEAPTLLITGNQH
                     SEMAKQADMCLVISQEEYDFAKVATFSSQIAFDYVLNTLFSVIYSQNFEENIRNLKNK
                     QELMQKGLLKEYRKT"
     gene            complement(76027..76869)
                     /locus_tag="LLC22_000380"
     CDS             complement(76027..76869)
                     /locus_tag="LLC22_000380"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338272.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5433687.1"
                     /translation="MKPKKRKLLDLLMLFLLLSGIGILAYPFVSDALNNYLDQQIISH
                     YQQQAVKENEEVMAKIQENMTKKNQQLAKEGGNPGADPFTKKKEPAKKDRTYFEKHTI
                     GILTIPEINVHLPIFDETNTVLLEKGASLLEGTSYPTGGENTHAVISSHRGLPQAKLF
                     TDLPKLTLGDSFYIEINGRTLAYQVDQIKTVEPTDTKDLRIEKGQDFVTLLTCTPYMV
                     NSHRLLVRGHRVPYHAKEVQKEVQKVSENKRFFLYGLLAACILIFLLLIYLFRQSFKI
                     RNRS"
     gene            complement(76961..78838)
                     /locus_tag="LLC22_000381"
     CDS             complement(76961..78838)
                     /locus_tag="LLC22_000381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBK5433688.1"
                     /translation="MKNHKKINVMLGVLFLILPLLTNSFGAKKVFAEETAAQVILHKK
                     KMTDLPDPLIQNSGKEMSEFDQYQGLADISFSVYNVTQEFYAQRDKGASVDAAKQAVQ
                     SLTPGTPVASGTTDADGNVTLSLPKKQNGKDAVYTIKEEPKDGVSAAANMVLAFPVYE
                     MIKQADGSYKYGTEELDTIHLYPKNTVGNDGTLKVTKIGTAENEALNGAEFIISKEEG
                     TPSVKKYIQSVTDGLYTWTTDQTKAKHFITGHSYDIGNNDFAEASIEKGQLIVNHLEV
                     GKYNLEEVKAPDNAEMIEKQTITPFEILANSQTPVEKTIKNDTSKVDKTTPQLNGKDV
                     AIGEKIQYEISVNIPLGIADKEGTQNKYTTFKLIDTHDAALTFDNDSSGTYAYALYDG
                     NKEIDPVNYSVTEQTDGFTVSVDPNYIPSLTPGGTLKFVYYMHLNEKADPTKGFSNQA
                     NVDNGHTNDQTPPSVDVVTGGKRFVKVDGDVTSDQTLAGAEFVVRDQDSDTAKYLSID
                     PSTKAVSWVSAKESATVFTTTSNGLIDVTGLKYGTYYLEETKAPEKYVPLTNRVAFTI
                     DEQSYVTAGQLISPEKIPNKHKGTLPSTGGKGIYVYIGAGVVLLLIAGLYFARRKHSQ
                     I"
     gene            complement(78835..80256)
                     /locus_tag="LLC22_000382"
     CDS             complement(78835..80256)
                     /locus_tag="LLC22_000382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBK5433689.1"
                     /translation="MKKLGWLSMCLFLLLFKPAFTQVATETETEMVQITLHKLLFPNG
                     QLPKNHPNDGQEKALLQTYRGLNGVTFQVYDVTDSFYHLREKGKTVEEAQAEIAKNGA
                     SSGMFTAEATTTTLNNEDGIASFSLAAKDQEKRDKAYLFIESKVPEVVKEKAENMVVV
                     LPVHGQNNQKLSTIHLYPKNEENDYPDPPFEKVLEEPRNDFTIGEKITYSLHTTIPVN
                     ILDYQKFELSDSADEALTFLPNSLTISSNGEKLTEGFVIHKKPHGFDVLFSIPSLEKY
                     AGKKLTISYQMQLSSTAQANKEINNNGTLDFGFGVSTKKVSVYTGSKQFVKIETNKPD
                     KRLAGAVFLIKNKAGNYLQQTANGYKWTKNESDALHLISDKNGAFSISGLKTGSYRLK
                     EIEAPSGYILSETEIPFTISTFLSEDKEADSILKVVNKKENSRPFLPKTNETKNTLLG
                     VVGMVFASFAIWLFIKKRTGVKK"
     gene            complement(80259..83648)
                     /locus_tag="LLC22_000383"
     CDS             complement(80259..83648)
                     /locus_tag="LLC22_000383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VWA domain-containing protein"
                     /protein_id="HBK5433690.1"
                     /translation="MTTTGKKLKVIFMLIILSLSNFVPLSAIADTTDDPTVLETISAE
                     VISDQSGKKALNIKLNANNTSAEKIEKEIGLVENYLSDVERKEGDGYAYQVNSGKITL
                     EISSNTKQTIDLSFPIDPALYHSQANKLIVDNKEYDIIDETENKKDTDVSVPKPDEIE
                     EESSKENENSVSPFTLPTLSLPAVSVPSNQTIPTEYTTDDQGTYPKASWQPTGNTNVL
                     DHQGNKNGTNQWDGINSWNGDPNDRTHSYIEYGGTGNQADYAIRKYAKETSTPGLFDV
                     YLNARGNVQKDITPLDLVLVVDWSGSMNDNNRIGEVKIGVDRFVDTLADSGITDKINM
                     GYVGYSSEGYSYSNGAVQMGSFDSVKNQVKSITPSRTNGGTFTQKALRDAGSMLSVPN
                     GHKKVIVLLTDGVPTFSYKVQRVHAQSSSNYYGTQFSNTQDRPGNTSLISRIYDAPDQ
                     NNLSRRIDSTFIATIGEAMALKERGIEIHGLGIQLQSDPAAGLSKAEVESRMRQMVSS
                     DEKGDLYYESADHATDISEYLAKKAVQISATVSNGQINDPIAEPFIYQPGTLSVKSVG
                     TSPTTVTPSISIEGNTIKSNQIYLGKDQEIQIHYQVRIQTENEDFHPNFWYQMNGRTT
                     FQPNIDTNELAEFGIPSAKAPGVSLHIKKLWEEFDNNLADRPDQVTFEIQREHTTNAA
                     AWKNGYIRIIKPAKDTTNTWERADIDKLSANSGESYQEILSLPQYNNQGQAFSYQTIK
                     ELPVPGYDSQQIDAMTWKNTKQFTPLNLKITKNSSTGEKDLIGAVFKLTGDSIDTLLT
                     DHGDGTYSLPENVKLQKEMTYTLTETKAPEGHGLSKKTTWEIKIASDGTVTIDGKTVT
                     TSDDTIQLTIENPFVEVPVAVRKYAMQGTDKEINLKGAAFSLQKKEANGTYQPIDSQT
                     TNEKGLASFDSLTPGKYRVVETAGPAGYDTSPGNYEFQIDKYGKIIYTGKNTEMTNNV
                     WTLTHQNRLKAFDLTVHKKEDNGQTLKGAKFRLQGPEMDLESPKDGQETDTFLFENLK
                     PGTYTLTETFTPEGYQGLKEPVTIVIHEDGSIQVDGQDHESVLSPGAKNNQISLDITN
                     QAKVPLPETGGIGRLGIYLVGMIGCAFSIWYLFLKKERGGS"
     gene            83905..85297
                     /locus_tag="LLC22_000384"
                     /pseudo
     CDS             83905..85297
                     /locus_tag="LLC22_000384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351559.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            complement(85370..86017)
                     /locus_tag="LLC22_000385"
     CDS             complement(85370..86017)
                     /locus_tag="LLC22_000385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328434.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBK5433691.1"
                     /translation="MTMKGYPRIIRDKGEMWMPKETFFNLSNAKKQRIDDLLLEIFCS
                     QHISQVKVSEIVDKMGMSRGAFYKYFQDLEDAYLYTIKSSSHIVHQDILKFISENKQH
                     FFLGIEKYLEWCCDLDHESIYWQRLYLLTQRNDQQTTKRRELSADSPMNEKWLELLRI
                     NHFSIQSSEEAVSFLYFSMTLVMNTLTDLIANNWTKEELLKDFRYKSRWIAEGIQ"
     gene            complement(86025..86711)
                     /locus_tag="LLC22_000386"
     CDS             complement(86025..86711)
                     /locus_tag="LLC22_000386"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5433692.1"
                     /translation="MKKILTMKKVTKTFGSGHTKVSALKAIDFYVKEGEFVSIIGPSG
                     SGKSTFLTISGGLQTPTSGEIVINGHSLTELPEKKRADLRFKEIGFILQSSNLIPFLT
                     VKEQFELVDQVTSKKEDSTKIDSLLQSLDIQSLKNSYPKDLSGGERQRVAIARALYNE
                     PSLILADEPTASLDTDHAYEVVKLLVKEAHEKQKATIMVTHDVRMIQWSDRVYRMEDG
                     YLTEEEKKKE"
     gene            complement(86717..87790)
                     /locus_tag="LLC22_000387"
     CDS             complement(86717..87790)
                     /locus_tag="LLC22_000387"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5433693.1"
                     /translation="MFLAIKEIRYSKLRYGLIVGIMFLIAYVVFMLSGLANGLSEEFK
                     KAIDDWDAQEIVLSEDANQVFAASQLTRGDLKYIEGGEKAPIGLYSGAIKGKNKENVT
                     VFGTTKEAFLLPKLTKGHEFKTKNEIIISQNLADSGYKIGDTIKIGSYDDPLTIVGIF
                     PETYYTVSPVIYASLDTWTALKYGQQPFASEEEQPINGIVIKDSAKISKEKASKGLQL
                     LTIGTFIESIPGYSAQNMTLNAMIYFLFLVVAAVVGIFMYVMTLQKTAIFGVMKAQGI
                     KNFFIAKSLVAQSFIVGVVGVLLALLFAYLTSLILPSAMPFAVFWSQWLLYSGILIIV
                     AMLGGLFSIRTITKVDPITAIGG"
     gene            88012..88686
                     /locus_tag="LLC22_000388"
     CDS             88012..88686
                     /locus_tag="LLC22_000388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5433694.1"
                     /translation="MIKLLVVEDDKVLSNNIKEILAAIGEITQVYDGSEGLFELESGV
                     YDLAILDLMMPEMNGYEVLAKIRKEKIQTPVLILTAKDSLEDKIEGFERGADDYLTKP
                     FYREELIMRVKALLKRSLGLFDENVLKYKDISCDLKSNEVLYKEQVLPIQGKEFELLV
                     YFLQNKGIILTKEQIFDRIWGFDSDTTITVIEVYMSNLRKHLRSTGLDKEIKTLRNVG
                     YILQRV"
     gene            88691..90031
                     /locus_tag="LLC22_000389"
     CDS             88691..90031
                     /locus_tag="LLC22_000389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5433695.1"
                     /translation="MNGDITRKQRSRFFATNVAAFAFIFFLLGFITLQILNQSAYRET
                     DLSLEKINFDSRTVQLEIQRYQQGDPFLNPTQTEQNRTNMEQPLMEPSNDRFNTQVIL
                     WSKNGEILNKAAIGGRFNQIKELKMDTKNLNTIQNIELNEDSGSSALSFRSITKKAET
                     NQDGVAYIQILENTNQIKNSLATFRTIMILCMIVFWILSIGISYYLSSLSMRPIILSW
                     RRQKEFVENASHELRTPLTIIQNSLEHLFTKPNHTIIEESESIAQALSETRRLTGLTS
                     DLLTIARNDSDQQLLSKQMINTQEYIEQLVKPFQEMAIIDGKEFILHNDATLEVPIDE
                     KKIHQVLVILLDNALKYTNPEDKIILDSSVNHKEWLIHVKNTGPSISEEDQARIFDRF
                     YREDQSRAKETGGYGLGLAIAKQVIEQHHGQISVSNYLPQGVDFKVQLPLKPKK"
     gene            complement(90180..91166)
                     /locus_tag="LLC22_000390"
     CDS             complement(90180..91166)
                     /locus_tag="LLC22_000390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2382 domain-containing protein"
                     /protein_id="HBK5433696.1"
                     /translation="MEEKNLTVIGSYSTREEALSVIERLRNEGYERDDIVIYTTDEAA
                     SRLGFDGLSGIDVETDENRMDGEEDRSLWEKIKDTFSFDTYDSETATPENDPLYQYRG
                     DISDGKFVITVKGYRQPETTEDTMDTQDTVSPASTMGTGLETGTGTDPMDVGGTTGFQ
                     NTTDPLNMTPGTDPMDVPGETDTMGTSKTEDIDRKPNLDDDTIQLKEEKLDVNTHDVT
                     TGEVDIHKHVVNDTETVEVPVKREEIVIERKPVTDQSSQGTDEKLEDDTITIPIKEEQ
                     VDVSKHTVIREEVGIHKEEHEDVEKVTEDVSREELDIDTSGDVHIEDRNKKS"
     gene            91890..92921
                     /locus_tag="LLC22_000391"
     CDS             91890..92921
                     /locus_tag="LLC22_000391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5433697.1"
                     /translation="MDSKTRKQLQEKLKQRTHLLPSVFQQFLEENRSSLSLGSRYEYA
                     KDFHLFTDYLRKVFSEEVDDQLIIHLEKQDYQNFLAKIYRHTRSFQTTANQETEQLFE
                     NSYYGISRKQYSLNHFLRFLYQKGLIEEEISLLGTSLPETTKAAPRYIDAELFKDFEH
                     LFIPIEGFQTSREASFEEKNRPRNLAITAILLYCGLKIHEVVELKRKDVSLTKQILNL
                     NRKENRLNKVPIPKEAMPFLENYFKLTAQNTDENSFVFRSSHDQQISPRTIRQILSKI
                     TVYKNVSPELCRKTYRYYAELYLDDADAVNYLCGNRYLSSHSFQDIWEKMVDFSYHEL
                     AAFVRVSSI"
     gene            93030..>93454
                     /locus_tag="LLC22_000392"
     CDS             93030..>93454
                     /locus_tag="LLC22_000392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBK5433698.1"
                     /translation="MMETITYSPLNLFTNFQEAAANFSETPIIFDEPLSAFPELGLET
                     TYKKCCESVLKRAYQLAHLGVKSGDKVIIYKSSAFDTYLLAVSVSYLGAVPVMTSYHL
                     PTTTMEVFIDRLEDPFILFDDETKKRVREISNGTKSKQIP"
BASE COUNT        29894 a        16576 c        18963 g        28021 t
ORIGIN      
        1 ttaaaagtat aatttaatta attaagtttg ttttaagaag agaacttttt attaagtttt
       61 tttattttga ggaggaattt gaatgcaaga gctgaagacc cgcagtgccc ggcaccatag
      121 acctaaaaga aaaatggtga tcaataaaaa agcgattgct cctttaattg gaacgagtct
      181 tttagttggg ccgatgatgg ttacagcggt accgcaacat gttcatgcag atgaacaagg
      241 atctcaaaca gtcgctgatc ctcaagcgtt tatcgatcaa atcggctggt ctgcgtcaga
      301 agttgctgca agtaatgact tgtatgcttc agtcatgatc gctcaagcgt tgttggaaag
      361 tgcatatggc acttccggat tagctagtgc gccaaattat aatctattcg gtgtgaaagg
      421 aagctataac ggacaggtcg tttatatggc aaccaaagaa tatgtaaacg gacaatgggt
      481 aacgatgaat gagccattcc gaaaatattc ttcttattgg gaatccttcc aagaccatgc
      541 gaatgttctt cgttcaacca gtttttccac gggcgattat cattatgctg gcgtgtggaa
      601 aagcaataca acaagttttt atgatgcaac agcgtacttg acaggtcgtt atgctaccga
      661 tccaaattat ggggccaaat tgaactcatt gattaatact tataatttaa cccgttttga
      721 tacgccatca acaggttcgg ctacaacaac cacaagtaca acaacaacga ctactacgac
      781 gacttcaacg tcatcatctt caacaacaga tgtaaataca aataatggtc agacatatac
      841 agtcgtgtca ggtgatacgc tatgggatat tgcacaaaaa tttggcatgt ctgttgatga
      901 tctaatggcg aaaaatggca tgtctatgtc cagttattct ttattagttg gtcaagaact
      961 aaacgtttga tttagataaa aaggcaaaga aattaccata tatggtatat ctttgtcttt
     1021 tttttgctag tcaaagacga atcactcgcc ataaatgaac agattgtatt atgataagta
     1081 agaagagcaa agacaaggag gaattgaaga tgacagctat ctataactca gtcaccgaat
     1141 tgattggcaa aacgccaatc gtcaaattaa ataaaatcgt accagaagat tcagcagatg
     1201 tttttgtaaa gcttgagttt tttaatccag gaggaagtgt aaaagatcgt attgctttaa
     1261 gtatgataga aaaagcagaa cacgatggtc tactgaaacc aggtgatact atcattgaac
     1321 ctacttctgg aaatacagga atcggattgt cgatggtagg agttgcaaaa ggatataaag
     1381 taatcatcgt gatgcctgag acgatgagta tcgaaagacg tttattgatg aaagggtacg
     1441 gcgcagagtt gattttgact cctggtgcgg atggtatttc tggatcaatc agagaagcag
     1501 aacgtttggc aaaagaaaac ggctactttt taccattaca atttgaaaat gaagcaaatc
     1561 ctcttgtgca tgagaagacg actggtcctg agatacatca agcatttgga gtaaatggct
     1621 tggacgcgtt tgttgcaggt atcggtacag gaggaacgat cactggcgct ggccgagaat
     1681 taaaacgtgt gtatccgaaa atcgaattaa tcggggtaga accagcagaa tctgctattt
     1741 tagaagggaa agaagcggga cctcacaaaa tccaaggaat cggtacaggt tttgttccta
     1801 aaacactgga tacttctgtg tatgataaag tcctttctat tagtggagac gaagcgatgg
     1861 aaacagctag agaagttggg cgaaaagaag ggattttagt aggcatctca tctggcgctg
     1921 caattgctgc cgcgctaaaa gtcgcaaaag aattaggaaa aggcaagaag gtattagctg
     1981 tggttcccga caatggtgaa cgttatttat ctacagccct ttaccaagag atataaggca
     2041 cttggttttt ctccagatag gtttatgtaa aaaactttta aagatgaaaa gaacacacaa
     2101 aaatttatga tgagaaaaat tatttgaata gagacgtaga atagtgaacg cgactgtttt
     2161 acgtcttttt tcattaaaat acaataaaat tgaattttct tttcatgtta agtggatttt
     2221 aaaatgtaaa aatagtatga taagacgaga ataacaacgt ggggtgttta catggaaaat
     2281 aagttagtcg aagaggttat cgaaaagtta aaaaaagaga acattcgaat cacacctcaa
     2341 cggtacgcgg ttttagaata tttgattgaa catcattccc atccaacggc tgatgagatt
     2401 tataaagcac ttgaacatcg gtttccaaat atgagtgttg cgactgttta caataacctt
     2461 cgcttattta cttcgattgg atttgttcaa gaaatgaagt acggcgatgc ttctagccga
     2521 tttgatttca gttcaaagcg tcattatcat gtaatttgtg aaaactgcgg taagattgtt
     2581 gattttcatt acccagggct tgaagatata gaaatggctg caagcagact gactgatttt
     2641 gagattaatg aacatcggtt ggaattgtat ggactctgtc cggattgtaa agagtcagca
     2701 aaaaaggcgc aaatgtaaaa acagtttcta caagtgttat acctaaaaaa agctagctgt
     2761 gtaaaaaaaa cgctagcttt tttatttttt tgtcttttat tcacaatctt agatataaaa
     2821 gtgaatatta ttaaaataag aatcttgtag atattgggtt cttatgcttg aaaaggaatg
     2881 aaactacaaa caaacctttg tgaattcaca agcattaaac tgttgtatcc gttttatttc
     2941 tgttatagta gttttgtcga aggacaaaat gttaatcgga gggaccataa atgaaagtag
     3001 tagtaattgg ctgtactcat gcaggtactg cagctgtaaa aagtatttta aaaaatcatc
     3061 cagaagcaga agtgacagta tatgaaagaa atgacaatat ttctttctta tcttgcggta
     3121 tcgcacttta tgtcggcgga gtagtaaagg acccagcagg cttgttctac tcaaatcctg
     3181 aagaattatc ttcattagga gcaacagtta aaatggaaca cgatgtaaca gacgtcgata
     3241 cagaaaataa aacagtaacg gcaaaagatc tgaaaacagg agaaacagaa acggtttctt
     3301 atgataaatt agtgatgaca actggttcat ggcctattat cccaccgatt agtggaatcg
     3361 atgcgaaaaa tgtactccta tgcaaaaact acaatcaagc aaatgaaatt attgcacaag
     3421 cgaaagaagc aaaacgtgta gtaattgttg gtggtggata tatcggtatt gaattagtag
     3481 aagcttttgt cgaatctgga aaacaagtga cattgattga tggattagat cgcatcttga
     3541 ataaatatct agataaacca ttcacagata tcttagaaaa agaattgaca gaccgcggtg
     3601 ttactcttgc gctaggcgaa aatgttactg aatttatcac agatgaagaa ggaaaagtga
     3661 aacaagtagc tacaccaaca gatacatttg atacagatat ggtcatttta tgtgtgggct
     3721 tccgtccaaa tacaaaactg atcgaaggaa aagtagatac actgccaaac ggggcaatca
     3781 aagtgaatga atacatgcag acaagtaatc cagacatttt tgcagctgga gactctgcag
     3841 tagtcaacta caatccaagt ggcacgcaaa actatattcc tttggcaaca aatgccgttc
     3901 gtcaaggttt gcttgtggga aataacttga cagatcataa aatggcgtat cgtggtactc
     3961 aaggaacttc aggactttac ctatttggct ggacgatcgg ttcgacaggt gtgaccaaag
     4021 aaagcgcaac tttgaacgat ctagaagtcc aagcgactgt atttgaagat aattatcgtc
     4081 cagagttcat gccaactact gaaaaagtaa tgatggagct agtctatgaa aaaggaacga
     4141 atcgtatcgt aggtgctcag ttcatgtcca aatacgacat tacacaatca gcaaatacca
     4201 tgtctttagc tgttcaaaat aaaatgactg tagaagatct cgcactttca gatttcttct
     4261 tccaaccaca ttttgaccgc ccatggaatt acttgaacct acttgcacaa gcagcgctag
     4321 gcgaaatcga aactgcacaa taaagaaaaa gggttgtgac acaattttgt cacgaccctc
     4381 tgtctttttt tgtgaaaagt acaattagtt gtctttcttc gaattttttg tcacaataag
     4441 cagcaaagat aaagctgtta cataaaagaa caagcagctt tatttgattt tgaaaagaaa
     4501 ggtgagaaag aagatgaata aagaatattt tgtccaacaa gatgcatttt tagaagatta
     4561 taaaagtgct tcgaagaaat taacgatcaa tattgatgag ttggcagatc aagtactctc
     4621 tcagttgaat gaaacgcaag aggaatatta cacgatgcca gcaaatgacg ccaaagataa
     4681 tgtttctcat cgttttcctt tcagtagacg catctactca gatgaaaatg acggcacatt
     4741 gaatacagag tacacatatg aaggtcagcc atatgtgcta gaaactgatg atgatcttta
     4801 aagacagttt ttgaaaaggc cgctcatcct taagtgatga caaaaaatca tcacaattac
     4861 cgatgactgt ctctttacta tcttttaatc agaaaaaggg gttatgacaa gctttgtcaa
     4921 cccctttttt tcttggtttc agattgggtt ttcctacaaa atatttttat ctttgttgaa
     4981 taggaaacaa aaaaacaata taatgaaaga aaaagaaggt gtagaaatgg ataaaagaca
     5041 actgctaata gaagaatatc tggatttagc taatgagatt attcatcgta ataaaccaga
     5101 aatggaaaaa gaatttgcag gatttactct aaatgaacta gaagtgattg aacatatcgg
     5161 gaaaatccct gatcctaacg tgacaaaatt agcgaatgct agttacatga ctagaggagc
     5221 catcagtaag ctaacaaaaa aactgatagc tagagggatc ataaacactt atcaaagcga
     5281 agagaataaa aaagaaatct attttcaatt gacgccaatc ggacaaaaaa taaggaatag
     5341 acacgagcaa ctccatcaaa aatgggtaca gcgagatgct actgtatttg aaaatatgtc
     5401 aaaagaagaa tttgacacag tatttcgttt tatcggtcga tacagagaat ttatacgaag
     5461 tagcaaatga agctactatt ttttattgta gtgataatag gcaaaaatca taagcaaaaa
     5521 tccgaatacc gtcggaagaa atggtgctgc agcataaagc tgtcctgcga ttagcgggcc
     5581 gatgacgcgc gatagagatt gtatactttg ggtaccgccc attacaagac cttgctggtt
     5641 atctgagaca gaattggata gttggccatt gaatacagga gtaaaaatag aatcaccgaa
     5701 accataacag ataatcccaa ataaaaacaa aatcggcagt agaagaattc cagataatgt
     5761 gatgaataga taggcgagga tttcactgaa catccctatt cttgtgatct gctgttctga
     5821 aaattttttg agcaatcgag gcataatgaa caattgcgag acagtatcca agattccaat
     5881 caaagagaag cttaaaccaa ccaacccagc cttccactga aaggcgtcaa tcgaaaattg
     5941 agaaaagata gattgaagag agccagctgc caaccaaaca gcacaacctg ctgtcaataa
     6001 aggaataacg gatgaaatct tgaataattg ttgtaattgg tgaaaaggtc ttacatggga
     6061 gaaacttaaa tctactgaac gtttttttat tggaaggctt tctagcataa atgtgtagcc
     6121 ataaacggca tttaagaaag taaagagtgc tccaataaat ataggaacag aattccccaa
     6181 ctcagctaat agacccccta taataggacc cagcgttgtt cctataccga ctaaagcacc
     6241 catccatcca aaaactttgg ttctttcatt aggttccgtg atgtcggcaa agtaagcata
     6301 taaggtggag atttctcctg ccgtcaatcc ttcaatgata cgaccaagga acaacatcca
     6361 tatcgaattt cctaaaccaa aaagcaaata tccgatactt gatcctaata aactgataat
     6421 aaggatcgga tgacgcccaa aatgatcact taagctaccg agaatggggg cagataagaa
     6481 ggcagctaga gcataaacag acatgagcaa agtgatatag aaagcttgct gatgtatgga
     6541 gtgagaataa ggcagcgtta aaaacggaag tacaggactg acgatagtaa atcctaatcc
     6601 agtgaataag acagagacgt atccaaaaac tttagaatgt ttatttgtga aactgtacat
     6661 gtaaaaactc ctttatgcaa taatgttaac ttggaaacaa aaatagtgta tagtaatttt
     6721 gtttccttgt caacattcta aggaacagcg aaatctactt aatttattta ttccgaaaag
     6781 tgaagatacg catcaaaaac atgaacaaac aaaaatcaag tagacgacat tgtaaatctg
     6841 accgatcagt gaagtaaata gaaaagaaac ctgttcttgc ttcccatgtt ttttttacgt
     6901 atactgtgat tgagcggagg agaaatcatg ttgaatttag aaaattactt aagcgctgga
     6961 caaacagtca tatctaatct tttacttaaa aattatcata ggatcggtct acaatctgaa
     7021 gaatttttat ttgttctaca gttgcatatg gcacagcttg aaggagatac tttccctgat
     7081 ttgcagatga ttgctatgga tatgggaatc aaacaagatc agatttttca aatactggat
     7141 cgtctcgtaa caaatggatt tatcaagata gaaacgacga ttgtcaacgg taaaaaagca
     7201 gatcgatata atctttaccc catctatgat ctattaggtg agtatttaaa aacacaagaa
     7261 aaaaaatacg aagaaaaaac acaagaaaaa gaaatccagt cagtgtatca attatttgaa
     7321 caagaatttg gacgcccgct ttcttcgatc gagttccagc ggatcggaca atggctagaa
     7381 gaagaccatt atcagccgga aattttgaag ctagcactgc gggaagccgt attaaatcag
     7441 gcttatagtt ttaattacgt tgaccgcatt ttgctatcgt gggaaagaaa aaatctacgt
     7501 acaaaacaac aagtggaaga agaccaaaaa cgaagaaaac agcagcttct tcaaagagaa
     7561 gtagaacagt cagctcaaca agaagaattg ccgaaagtct cactgaaaaa ttggttggag
     7621 gagtagcgga atatgttaag caaacaaaaa acaatggaag ctctagaaac gatgtatgga
     7681 atgtttcccg aagcacatgg agaactcaag cacaataatc catttgagtt attgattgca
     7741 gtgatcttaa gtgcccaggc gacagatgta tcagtgaata aagcaacgcc agatttgttt
     7801 gcctcttttc cgacacccga tgcgttagca gaagcttcaa tcgatgaaat cattcttaaa
     7861 ataaaaacga ttggtttgta tcgaaataaa gcaaaaaaca tcaaagcgtg tgcacagcag
     7921 ctgattgaac gtttcgatgg gcaagtgcca acgtcaagag aagaattgat gtctcttcct
     7981 ggtgtaggca gaaagacagc aaatgtcgta ttgggggatg cattcgggat accagcaatc
     8041 gcagtagata cccacgtgga acgtgtctca aaacgcctga ggatctgcaa actagatgct
     8101 acggtcatgg aagtagaaga aacactgatg cggaaagtac cacaagaatt atgggtaaag
     8161 acacatcata cactgatttt ttttggtaga tatcattgca cggcaagaaa tcccaagtgc
     8221 gaggtatgtc ctttgctatc aatatgtcaa gatgggaaaa atcggatgcg tctaaaagaa
     8281 aaggcgctaa aaaagaaacc acgcctgtag acgtggtttc tttaattgca aataaatgta
     8341 tgaattatct tgttattatg gagaaaagct gtttcgttta tcttttttgc atgaaaaagt
     8401 aaatgtacat actcagtagc taggatggta acttattaca atttattgcg ataaaaataa
     8461 aagttgttat ttttattggg aaaatacccg atgtagaaaa taatgccttc caatatacct
     8521 ataaaataag tccagtattc caaaggatta tataaataag tgacgtatct atctaaaggt
     8581 gtaataaaaa tgataagtga taataaaaaa ataccattta taactaaaca taaactaatg
     8641 gatttgggcg gtttcaggct catcagaaaa atatagattc tggtgaacaa caaccataaa
     8701 aaagtgagaa tcattgcatg agagcttctt tccataaatt ttcctttaag agtagtgctt
     8761 aaaagtacag aaaaaataat aaatgcaagg ataggagcaa ttaaagtaaa tttatttaat
     8821 aataaacaaa atttttcagc ttttttattc ttggaataac gaggtattgt tttcgataaa
     8881 aaaagatggt gcagacaaat tatgataatt aagcatacta tcagataact caaaatgaag
     8941 ccttctttca aaaaattatt caaaaccata tattgtattt tttatttgat aataacaatg
     9001 ggattattaa gaagtggcac taaataaaag actagtgtgt atttagccga tttaattata
     9061 aacaagtaaa tggataaagt atatgtaatg ataaaagaaa aatggatttt ctaattttta
     9121 agctaaatgt tagatcacac atgtatatgc tggatagtct tataaaaaat catgtaatac
     9181 agcttggtac atgattttta tttgtagctg ttttttacat agacacaaaa aagaaaccac
     9241 gcttgtagac gtggtttctt ttttactatc tgtttccaga agctgaggtg ctgctggatg
     9301 gtgtatggtc atttgcagca tccgctccgc tagttgctgg ctcactggaa gaagcaggag
     9361 gagcagatga agacggtgtc gagctttctt cggatgaaga agaaggaacc gttgttgaag
     9421 acgctggctc gcttgtttct gctgtcgtgc tttcttttga ggactcagca gttgattcgc
     9481 tttgactagt agagctagag ctttgagtcg ttgtctctgt tgttgagctt ccaggagtct
     9541 ggacatagct ggaagatgga atagttgttg atggtgtaat tgcattcgat ctagctgtat
     9601 attgatcttt gtagtacagt tcaccgccca cacgaattaa tccgcttggc atctcccagt
     9661 ctgtatttgt cacgttagct gaaacatact gcataagctc gcgataaaca tcagaggcta
     9721 cgtgtgacga ttctgaagtg acaggtgtca tttttttatt gtaacctgtc cacacggaaa
     9781 tcgaataatt tggcgtatag cccgcaaata ggatatctgg atacacccca gaagaaatac
     9841 caagttttgc atactcgtca tctgtgtaat tggatgttcc ggtcttaccg gcttgatata
     9901 acccagcgat ttgcgcattc gtaccagttc cttcagtgat cgtatctttt aaaatgtctg
     9961 tgatcatata agctgtttct ggagacatgg ctgtttttcc atctggctca taagtttctt
    10021 ctgttccgtc ttggaagacg attttattaa catattgagg tttgtaataa gtccctccat
    10081 tggcgaaagc cgcataggct gctgccattt ttaaggaaga agctccgtat tttgtcccat
    10141 cttgttcttc cgtattacta gagatcgcat tcgattgatg gatcgtactg tattcgatcc
    10201 caagattttt taagaaagaa gccactttat ctgaaccgac ttcattgaat aatttgactg
    10261 ctggaacatt acgggataag taaagtgctt ggcgtaaagt aatggtgccc atatattgat
    10321 tatcccagtt tcctacagga gtcgaagtcc cttcatagtt atacggtgcg tcagtaatag
    10381 tttttccagt agaatatttc aaatattcaa aagctggtcc gtaatctgtg acaggtttca
    10441 tcgtagaacc aaaatcacgg gaagtattca ctgctaagtt gttgcctaaa gttacgtctt
    10501 ctgcgatgtg acgtccgcca atctgggctt ttactttccc ggtattggtg tcgataaggg
    10561 tggaggcaac ttgcatctcg tcgtctgggt aagagacata ctgatccgtg ttgacgatat
    10621 catatagttt cttttgggcg tccagatcca aattcgtata aatctctaaa ccgtctgtgt
    10681 agacattctt atctgttttt tcttgtactt cattgatgac ttctttgaca taattatcga
    10741 cgatcttagt attgtcatcg gattgagtta gttcttgcag accatccgtt accggtacat
    10801 taacagcttg atcatattct gtttgagaga ttttttcgtt ttgaagcatc gtatacaaaa
    10861 cagtatctcg tcttttcttc gcctgatctg gataaacata aggatcatag gcggaagggg
    10921 cttgaggcat cccagcaagc aatgctgttt gcggtaaaga aagttctgat aatttcttac
    10981 caaagtacat ctcagaagct gtctccatcc cgtacaagcc gtttgacata tacactttat
    11041 ttacgtagta ggtcaagatc tcttgtttcg attttttttg ttccaatctt acagccatcc
    11101 acgcttcttg ggccttgcgt ttcagagtct gatcctcggc actggtggag aagaaggaaa
    11161 gtttgatcaa ttgctgtgtc aaagtacttc cgccttgcag tccgccagag gtaaagttag
    11221 agagggcaga accgatgatc cgaatagggt caaccccgat gtgtttataa aaacggcgat
    11281 cttctaccga cacgatcgca tcttctaatg ttttcggtaa ttcattcgca gaaatttttt
    11341 cacgcttttc tgcgcctaaa tcttcgaata gttcgccatc ttgtgtatat agtttggaag
    11401 atacggtagc gtctaatttt ttatccgtca attcgggcgc atcttttgcg taataccaga
    11461 aaagtcctac acctgctaaa aagaggatac agaaaaatga gagtattcct aaaaggatct
    11521 tgataaataa tcctttttta tgtgttccag aggactttcc agaacctttg ccagaattct
    11581 tcttcacact ctttttagga gtaggctgtt tctgtcgtct agagcttcta gtttgttcat
    11641 ttgccattct tgctttctcc ttcaatagat aatgttgata aatagaagtc aaccgcgtcc
    11701 aaataaggaa tccgcggaga aataccagtt ttgatctcta ttcctagttc ttcgatcaaa
    11761 gataaaggta gtgatttgcg tcctttttcc ttttgggcgt cccagtaagc aatcaaatga
    11821 acactattca aataaaaaca gcgcttcaaa gacgaaaacc ataacaagac aaagcagacc
    11881 ccattttgtt cgaggcatgc tttcatatgt tcgatttgat gggcatggaa gtttttaaag
    11941 ggaaaagatg ttttgttctt ggtttctttt gcttcaaagt ccaagtaaaa gcctcgatag
    12001 acgccattat agtctgtagt tgaggcttgg gtaaagtagg cttccttgat cacagcagca
    12061 cttctcttag gatagtctac tttcacgatt tggatagggg taggcttttt atggataacc
    12121 gccaacccgc gggaaagata atatttatta ctttcattga ttgcttcttc aaagcgcatc
    12181 ccccgattgc cgaattcagt gatctgattt cttttttctt gaattttttc gacgggagag
    12241 gcattcttat aataaggttg gccatttgga tagcgcaata ccatctttaa tcacactcct
    12301 aggccacatt atagcaaaaa agcggataga aagaaaagga atctgagatg gataagtcaa
    12361 aagtaatcta tgtgtctggg tatcgaagtt tcgaactcgg tgtttttaaa gaaaatgatc
    12421 ctaaaatcca agttgttaaa aatgttttaa aaaaagaact ccatcagtta gcagaagaag
    12481 ggctggaatg ggtacttgtc agtgggaatt tgggcgtcga actatgggct gtgcaaatag
    12541 tagcggaatt gaaagaagaa tatccggaac tatctcttgg tattttgtat cctttttctg
    12601 attttggtaa taactggaat gaagggaacc aagaaaaaaa acaattagca gaacaattag
    12661 cagattatgt cgaagctgtt agccatcaac cctaccaatc acctagtcag ctaaagaatc
    12721 acactcgttt tatacttgag catacagtgg gctgtctgct gatctatgat gaagaattcc
    12781 ctggaaaaac gaagtatttt tttgaagatg cacagaatta ccaagcagat catccctacg
    12841 aaattcggct gatcagtatg gacgatcttc aaaattttag tgaataatcg atattgtgtt
    12901 tgatttatca acttttttcc tatacaatga aaaaggtaga aatgttatta cgtaaatgaa
    12961 aactagaggt gtaaatatgg cgaatttggt ttatagtcct aaagacattt tacaacaaga
    13021 attcaaaaca aaaatgcgcg gctatgatcc cgttgaagtt gatgaattct tagacaatat
    13081 catcaaagat tatgaaactt acagcaaaga actccttgct ttacaagaag aaaacgatcg
    13141 attgagtgca aaagtagctc aattatctaa aactcaagga gcagctcaaa cacgcgtgca
    13201 acaaacagag gcaccaaaga gcgcagcagt gaccaatttt gatatcttaa aacgcttgtc
    13261 aaatcttgaa cgtgaagtat ttggtaaaaa gcttgatcaa caagcaagtg cagtcaaacc
    13321 agcacaacct aatccaaata actacacaaa tgcagacaca agcttagatg ataatgaaaa
    13381 aacacgtcaa ttttaatttt tgattaatga atttgcggtt ttcgggtaat cgcggtctga
    13441 cttgatcagg ctgaggaaag tccatgctcg cacaggctgt gatgcctgta gtgttcgtgc
    13501 ttagcgaaac cataagctaa ggtactcttt ggagtaacgg caggaaaaca agctaaggct
    13561 tcggctatgc ttaagtatcc ttgaaagtgc cacagtgacg aagcggctgg ggaaacccat
    13621 ccggtggaac gcggtaaacc cctcgagcga gcaacccaaa caatggtagg ggcgcttttt
    13681 gtctggaaga agaacaggac aaaaaggcag tataactgca gatagatggt taccgctttg
    13741 ttttttctcc ctggaaaagc aaagtacaga acatggctta tagaaaaccg caaacatcag
    13801 ggaattaggt cgtgacaaaa gtaatgcgtt ataagaaaca agaaaaacat ttgaaagcta
    13861 tttttcaata cttcagatga atcgttctta ttacaaaaca aacttttgta tcaccggtta
    13921 ttcggaattt gagtaaaagt gtggggtagg actgatgtcc cacctccttt ttttataaat
    13981 aaggagattg tgtatggaaa aaaacaggaa gttcaacctc gtcgcaactg cggcaagcgg
    14041 gctagaagca ctggttggta aagaattaag agatcttgga atcgaatgcc aagttgagaa
    14101 cggacgtgca cgttttgaag gaacaatgga aacgatcgct acagctaatt tatggttacg
    14161 tacagcagat cgagtaaaaa tcgtggttgg ggaattcgat gcgtatacgt ttgatgaatt
    14221 gtttgaaaac gtaaaagcat tgccttggga agattttctt ccactagatg cagcttttcc
    14281 tgtagctgga aaatcgatca agtcgaaact atatagcaca cctgattgcc aagcgatcac
    14341 aaaaaaagca atcgttgaac gtctccgtac ctattatcac cgtccagctt ctgtaccact
    14401 gacggaaact ggcgcacatt ttcagttgga agtagctttg ctgaaagacc atgtgatggt
    14461 aactctggat acgacaggac caagtttatt caaacgtggt tatcgcttag aaaaaggtgg
    14521 agcaccattg aaagaaaaca tggcagcagc acttattatg ttgacaaatt ggcgaaaaga
    14581 ccgtccattt tatgatcctg tatgtggttc aggtacgctt tgtattgaag cagccttaat
    14641 aggccataat atcgcaccag gattcaatcg tgagtttgct tgcgaatctt gggattggtt
    14701 cagtcaagaa atcatggaaa atgttcgatc agcagccgaa gaaaaagcag attatgatat
    14761 tgaattagat attactggtt cagatatcaa tggacggatg attgaaattg ccaaagccaa
    14821 tgcagaagaa atcggattag gctcttcgat tacctttaag caacaagcag tcaaagactt
    14881 caaaacggat aaagaatacg gggtcatcgt ggctaatccg ccttacggag aacgtctagg
    14941 agaagaagaa actgttcgga aattatataa agaaatgggc gatgtattcc gtccattaaa
    15001 aacatggagt aaatatatct tgactagcga cttagcgttt gaggaatttt acggacaaaa
    15061 agcaaccaaa aaaagaaaat tgtacaatgg tgcattgcgt acggatctat tccagtattg
    15121 gggaactcgt ccgcctagaa aaaaagagaa agacgaataa tcttactaat tgattcattc
    15181 aattggatgt ttggaggaat agggaatgaa agaaaaagag tttttacaag aagtaaaaga
    15241 aatcaatctt ctacaacaag ctttaggaat cctcgattgg gatacacaaa caggtatgcc
    15301 tgaaaaagct agtgcatacc gaagtgaagt agacagctat ctttacagca tttatttttc
    15361 aaaaaaaatc ggtccaaaaa tcaaagaagc cattcgctat ttttctgaac atccggaaga
    15421 attgtcggaa gttggaactg ccgtttttgc caaagtaaaa gaagagtatg atttggaaca
    15481 tcgcgtaccg gaagatctta tgagaaaata tacagctgcc gtttcttcag cacacggaca
    15541 atggcaaaaa gctagagaaa cacaacaatt ttctgatttt caacacgcat tgaatcaaaa
    15601 tattgaatta acaaaacagt tgatacctta ctggagaaaa gatgaaaaga cgaattatga
    15661 tgttttgctg aatcaatacg aacccgggat gactgtcgaa atccttgata aggtatttga
    15721 tcagcttaaa gaaggaattc tttcgatccg ccgtacgctc caagaaaaag ggactgaacc
    15781 tgaaacagac tttttaaatc ggagaatgac gaaaaaacaa cagaagagat ttgtagtgaa
    15841 agtaatcgaa caacttggtt atgattttag tcgtggtcgt ttagatgaca ctgtccaccc
    15901 atttatgact ggaattaatc cgaatgatgc acgaatcacg acacgatgga acgaaacaga
    15961 tttcaaaatg gctgtttttg gagtgatcca cgaggctggt catggtatgt atgaacaaga
    16021 catcgatgat aaatatgcgt atacaccggt ttatgaaggt acatcaatgg gtatccatga
    16081 atcacaatcg ttgtttaacg agatcattat tggaagtagt cgcagcttct ggaaaaagca
    16141 atatcctttc tttcaagaat gtgcagaagg aacattcgat gatattcctt ttgacaaatt
    16201 ttatcgttca ttgaaccata caaaatcaag tttggttcgt atcgaggcag acagtttgac
    16261 ttaccctctc catatcatca ttcgttatga aatcgaaaaa atgattttca atgaaggggt
    16321 agatgttgct gaactacctg aaatatggaa tcaaaaatat gaagagtatc tgggaatacg
    16381 accaacaaat gatgtggaag gcatcctaca agacgttcat tggtcaggtg caagctttgg
    16441 ttattttccc tcttatgcat tagggtacat gtatgcggca caattacttc attctttgca
    16501 gcaagaaata gatgtggaaa atgttctagc gtcagacgat tattctccaa tcaaaaactg
    16561 gatgtcagag catatccatc aatatggtgc atctagaaaa ccaaatcaat taatcatgga
    16621 tgcaacacat gaaccgctta atccgcaata cctgatcgac tatatgaaag acctgtattt
    16681 taatgtatat caggtaaaat aaaatacaat ttacaaagat agctgaaatt catctaatct
    16741 atagatgttt tcagctattt acttaagaaa gaagtggaac gaatggataa attacaagtg
    16801 atcgctgatt atagtatgga ccaattagcg catgatcaaa caggacatgg gagcgatcat
    16861 accaaaagag ttgtcaagtt agctgaaaaa attttggaga cggaaccgca ggcagaccgc
    16921 tttgtgacgc ttgcagcagc ttacctacat gatacgattg atgataaagt cgttaaaaat
    16981 gagaacgagg caaagcaaca gcttcgtgta ttccttcgct ctttgccaat agtagaggaa
    17041 cagatctcga tgattttttc cattatcgaa aatatgtcct tttctaaaaa tctctctgaa
    17101 gcggccgaac tatctctgga aggtaagatc gttcaagacg ctgatcgtat cgaagcatta
    17161 ggagcaatcg gcattttgcg tactgcttat ttcggcggtg gacatgggca cccgattttt
    17221 gatcctgaac tgtatccgca aacattcaag gacaaagaaa attaccgaaa aggcacgaca
    17281 gtgatcaatc atttttatga aaaactgttc ttgctgtctg ataaaatgaa tactgattac
    17341 ggatatgaag aagccaaacg aagagaaacc ttcatgcgtg aattcttaga agaatttttt
    17401 ctggaatggt ctattgacga tgaaaatttt actccagaca attggatcaa aaataacaaa
    17461 aaatgatgga ggttgtgaca gaagtggtca gctccaagat atttcggatc attttccgta
    17521 aaagttactt ctggaacact gtttaccaag aggtcgtgag cctgccgttc agctccgagt
    17581 cacaaggaac aatttcaaaa aatagcttct cgtgtttgat gaatattgta acttgtgatt
    17641 cggaattggc aggagaacac cgtttattcg gaagaatagg actgtgacaa gacttttgtc
    17701 acagtccttt tttcgaattc aacaagtaaa acttttaaga aatattcaga gagtaaaatt
    17761 aaaaattgct gataaacgaa gatggaaatt ttatgtattt ttattggtct atgcaataaa
    17821 taaattaaat attcagaata caattgattt taacgaaagg gcttctatca atggttgtgt
    17881 tgtatttatc tgcccaggta gagtaaaata gatcattatc taaaaggtaa ttgttcatac
    17941 tatataagtc atttgaaagt aaaaagatac tgtaaataaa aaatgtggtt aaataattct
    18001 cataatcagt gtaagcgtta tcaaaaatat agcatacttg ctttgtagat gaatgacacg
    18061 atatatgttt ggtatgttct gcaagacaga tgaatatgga ggtggagaca atgtcttcca
    18121 aagaactaac aatgtattta gagaaagaat tggatcaact gaaagaaaag gggttataca
    18181 atacgatcga catactagaa agtgaaaatg gtgcttgtat catcgtagac ggaaaaaaga
    18241 tgatcaatct agcatccaac aattatcttg gatttgccaa tcgcgaagaa ttgaaaaaag
    18301 catgtattga agcaaccgaa acttatggtg taggagcagg agcagtccga acgatcaatg
    18361 gttcgctgaa aatccatcag caattagaag aaaaaatcgc agaattcaaa gggacagaag
    18421 cagcaatcgc ctttcaatct ggattcaact gcaatatggg cgctatctct gcagtaatga
    18481 caaaagaaga tgctatctta tcggatgaat taaaccatgc atctattatt gacggttgcc
    18541 gcttatccgg agcaaaaatc atccgaatta aacatcaaga tatgaaagac cttgagaaaa
    18601 aagcaaagga agcgatagaa agtaagaaat ataaaaaaat catgtatatc acagatggtg
    18661 ttttctccat ggatggagac attgcacgat tgccggaaat tattccgatt gttgaaaaat
    18721 atggactgat cacctacgtc gatgatgcgc acggctcagg cgtaactgga aaaggtgcag
    18781 gaaccgtcaa gcattttgga ttaagcgaca aaatcgatat gcaaatgggc acgttatcga
    18841 aagctatagg tgttgttggg ggttatgtag ctggatcgaa aacactaatc gactggttga
    18901 aagctagaag tcggccattc ctattttcta cttcgctaac tccaggtgca gctgcagctg
    18961 cattggcttc gattactttg atgcaagaac atccggaact tgtcgaaaaa gtttgggaaa
    19021 atgctaatta ttttaaagaa gaattgaaaa aagtaggcta taacatcggt atgtctgaaa
    19081 cacctattac tccagtcatt ttgggagacg aaaaagtgac tcagactttc tctaagaagc
    19141 tgatcgaaca tgggatttat gctaaaccaa tcgtttatcc aactgtgcct cttgggacag
    19201 gcaggatcag aaatatgccg actgcggaac atacgaggga aatgcttgat gaagcagtag
    19261 cagtttatca aaaaatagga aaagaaatgg aaattattta actaaattta gttttttcgt
    19321 ctatttaaaa ttagagaaca tgttcacgca tatattgtta atcatctgaa gatagtagta
    19381 aaaaagatca gggaggatca tcatgaaaaa agtattggtg acaggatgtt taggacaaat
    19441 tggttcagag ttgatcacac ggctacgtca agaactaggc agtgaaaatg tcattgcgac
    19501 agatatacgc atgcctgaag tcattgagaa aaacgatatc tttgagatcc tagatgtaat
    19561 ggattacgaa aaaatgcgca gcatagcaga acaatatcaa gtggacacat tgattcattt
    19621 ggctgctctt ttgtcagctg ttgcagaagc aaaaccacaa ttagcctgga atttgaacgt
    19681 gactgggctg gtcaatgcat tggaagtcgc tagagaattc cagctgaaat tttttacgcc
    19741 aagttcaatc ggcgcgtttg gtccaaatac tccaaaagat cataccccac aagatactct
    19801 tcagcgtcct acaaccatgt atggggtaac gaaggtagct ggagaactac tatgtgatta
    19861 ttattatgtg aaatatggcg tagatactcg tggtgtccgt ttccctggat tgatttctta
    19921 tgcaaccttg ccaggaggcg gtacgacaga ctacgcagtc gatatttatt attcagcaat
    19981 caaagaagga aagtacacta gtttcattga tcaaggtaca tcaatggata tgatgtatat
    20041 gccagatgcg atcgatgcca ttataaaact catgaatgca gatcctgatc gattggttca
    20101 tcgaaatgcc ttcaatatat cggcgatgtc ttttgacccg gaagagatca aagcatctat
    20161 tcaaaaaatc ataccagatt ttgaaatgga ttatgatgtg gatcctgtac gtcagtcaat
    20221 agcagaatct tggccaaatt cactagatgt ttcttgtgcg caagaggaat ggggcttttc
    20281 gccgaaatac gacttagatg tgatgacaaa ggatatgttg gaaaaactga aagaaaaatt
    20341 ggtagagacg gtataaaaca agaaccacat ccaaaaagtt ttttatactt ttgggattgg
    20401 ctatggtatg aaaggggaca agggatggaa gaatatcaag ccacgccagt aaaagaagta
    20461 aaaatagaaa atgaattaaa acgtacgatg ggatttttta ctgctttatc gactgttatg
    20521 ggcacagtga tcggtgcagg ggtatttttt aaagccgcaa gcgtagcaga agttacagga
    20581 tccgccagtt tgcatatgtt ttcttggttt ctcggtggta tgatttctgt ctgtgcagga
    20641 ctaacaggag ctgaactggc agctgctatt ccagaaacag gagggatgat taaatatatc
    20701 gaacggattt acggaaatac agcagctttt ttattgggct gggcgcaagt cgtgatttat
    20761 tttccagcaa atgtagcagc cttgtcgatc attttcggta cacagttcgt caatctattt
    20821 ggtctttccc agtcaatgat tgttcccgta gctgttacag ctgctgtatc gatcctgttg
    20881 atcaattttt taggttctaa agctggaggg gcttttcagt cgattacgct tgtctgcaag
    20941 cttattcctt tgtttgtgat cgtcattttc ggtttgttcc gacaagaagg agtagacttc
    21001 caactgtttc cgatccaagc aggagaaaat ctttcatttt tctcagcctt gggagcgggc
    21061 ttgctagcaa cgatgttcgc atacgacggt tggatacacg taggaaatat ttcgggagaa
    21121 ttgaaaaagc cggcgaaaga tttgccaaaa gcaatttctt taggaatcat cggaatcatg
    21181 atcgtttatt tattagtaaa tgcggtgttc ttaagaaccg catctatcga cggagtcgca
    21241 ggaaacagca atgcggcaag tgacgttgca aaaatgattt ttggcggctt cggtggaaga
    21301 ctggtcacag ttggtatctt gatttctgtt tatggaacca tcaatggcta tacccttact
    21361 ggaatgcgtc tcccttatgt tatggcaaaa gaaaacaacc tgccttttag caagctcttt
    21421 gctaaacttc atgataaaac taaagttcct gtagccgcag gtatcttaga gctagtcatc
    21481 gctattggca tgatgatgat cggtggtttt gatacactaa cggatatgct gatctttgtc
    21541 atttggattt tttatacgat ggtctttgtt ggtgtcattc ttcttcgtaa aaaagaacct
    21601 gatttgtttc gaccatacaa agttccaatg tatccgttta ttccactagt agcaatcatt
    21661 ggagggactt ttatcgtatc aagcacgctt atcactcaga cctttttagc ttcgatgggg
    21721 atagtattga cacttgctgg tatcccgatt tatctctatt taaaacgtag atagctaaaa
    21781 cattcgaatt ttattagaac tgcacttctc tgccaaacaa aatattttat ttaaatgagg
    21841 agtacgtgga agaaatgtca aaagtactcg ttaattttga tcacgtaaat gtcgttttgt
    21901 ctacgatgaa atagcaaagt aaaagacaga aatcgggctc aaccgatttc tgtcttttac
    21961 tttgatttgc gtaactgaac tattcggcgt acgccgcgat aaatatttaa taaaaccaag
    22021 caaccagaaa tgaaaatggg aagccaaatc agatagacag ggtagccaag cactttagac
    22081 aaagcatgtg gagtcatttt atccatttca agaagtgctt gctgccaagt ctgaagattg
    22141 aagactagca tgaaacccga aataatcagg agaataaatc ctaaataatg aattgtagtt
    22201 ctttttctta cataagcgat cgtagcataa aggaacagta aaaaaatagg tacgccaaaa
    22261 acaaagtaca tattcagcat ctcgacaccc cctttgtgtt tatcttactt tactttgaaa
    22321 gaaatgagaa ataatagcct cgttacttgc ttgaaacagc aaaggactgc taagataaga
    22381 gagatacaaa gaatcaagga ggagtcatat ggcaagttat atcgaaccga ttcgttttgc
    22441 gctgattgtt tttccatttt tagccttagc gatctcatct gtttttttta tttatgaata
    22501 tcgaaagtat ggaacatttc tagtaacaag ggcagttatt ttgtattctt tcgtttttta
    22561 tttattgtgt gcgtattttt tggtgatctt accacttccg gcaaaggaga cggttgccca
    22621 aatgacaggg ccaaagatgg agctgcattt atttgcttca tggcaacatt tcagagacaa
    22681 cacggtattg gtcttgtctg aacctagtac ctacctgccg gcaatgaagc agagtgtatt
    22741 tttggaacca gcttttaatg ttttattact cataccattt ggcatttatt taagatatta
    22801 tttccggctt tcttttatga aaacgatgat tgctagtttc tgcctttctc tattttttga
    22861 attgacgcag ctaagtggac tttattttat ctacccaaga ccataccgct tatttgatgt
    22921 gaatgattta gtgacaaata cattgggtgg aatcattggt tttgtcgtta cgccgttatt
    22981 tacatttatg cttcctacaa gaagacgaat ggatgaactt tcttatgaaa aaggaaagac
    23041 tgtctcattg actcgacgct tggtcgctta tttgatcgac tggacatttt tatctcttat
    23101 taatttggta gcggcgattt tctttaaaat tgcgttcgat tcaggggcag ttacttctca
    23161 tatctggtgg cttttattag aagtaggggt atactttatg attgtaccgt ttataaccaa
    23221 tggatggaca cttggcaaaa aaattgtgcg tatccgtttg gtggaagaag accgcgaacg
    23281 aatttcttta aaagcattga tgatccgcta cgggtatctg tactttcttt tttatggttt
    23341 aagctggttg gggcagttgc ttcagcaaat catgaattcg acaacgaata cggtgttgca
    23401 gatgagtgca gtattcattt ctctcggtgt cttgttacta caaggtattt ttattttaaa
    23461 tatcttgcta tcatttttga gaaaaaaacg gattctgttt tatgaaaaag ctagtcacac
    23521 atatactgtt agcacgattg gccaaacaaa ggatgatgat tctcgaaatt agctgagcaa
    23581 aaacgctttg tctgtgttat aatgccaaag tcgtgataat ttaaagagaa gaggtgcacg
    23641 aatgaataat tttgatatat tccgcttcaa accgtttatc aatgaagcgt taaccgcaaa
    23701 gggcttcaaa cagcccacag aggtccagga acgtttgatt cctttaattg caaaaggaaa
    23761 aaatatcatt gggcaatctc aaactggtac aggaaaaaca catacgtttt tgttgccttt
    23821 gtttgaaaaa atcaatgcag aaaaagagga agtacaagtt gttattacag ctccaagtag
    23881 ggaactagct gcacagatct atgaagcagc tacacaaatc gctaaatttt ctacaccgga
    23941 gatccgtgtc tcgaattttg tcggcggtac agacaaacag cgtcaattaa atcgtctgca
    24001 tcaccaacag ccacaggttg tagtaggcac gcctggtaga atattagaca tgatgaatga
    24061 acaagcgctg aagattcaca ccgcatttgc atttgttgtc gatgaagcgg atatgacatt
    24121 ggatatgggt tttttaaatg aagtagacca aattgcaagt cgattaccag aaaagctgca
    24181 gtttttagtt ttttctgcca ctattccaga aaaacttcgt ccattcttac gaaaatacat
    24241 ggaaaatcca atcattgaag aaatcaaacc aaaagcagtt atttctgaag acattgaaaa
    24301 ttggctgatt tcaacaaaag gtaaagatga gaatcaaatg atttatcaac tgctgacaat
    24361 tggtcatcct tatttagcaa tcgtatttgc caatacaaaa cagcatgtgg atgaaattgc
    24421 cgattacttg aaaaaccaag gcttgaaagt agcaaagatt catggagaca tcaccccaag
    24481 agagagaaaa cgagtgatgc gacaagtaca gaatctggag tatcaatatg ttgtagcgac
    24541 tgatttagct gctagaggga tcgatatcga aggtgtctct catgttatta atgcagaaat
    24601 tccagaagat ctagacttct ttatccatcg tgtcggacgt actggacgta atggcttaaa
    24661 aggaacggcc attacgttat attcgccaaa tgatgagcaa gccattgatg cgatagaaaa
    24721 attgggcgtc tcatttgaac caaaagaaat caaaaacggg gaaatcgtca aaacatacga
    24781 tcgtaataga cgtgccaaac gagaaaaatc aaaagatgta ttagatccca cgctgattgg
    24841 tcttgtgaag aagaaaaaga aaaagatcaa gcctggttat aagaaaaaaa tcgattgggc
    24901 aattgcagaa aaaaataaaa aagaacgcaa aatcgaacgc agacagcaaa gccgtactgc
    24961 tcgtaaaaat aagaaaaatt cacataaata aaaaacaaga ggttgtgaca aaaggcgtgt
    25021 cacaatctct tgtttttaag ctagactttt tttcattccg atacaaagta cttcatcttc
    25081 aataaaaggt tctgtgcaag tatgataccc ttgtttttca taaaaatcta cagccgtcat
    25141 ttcagctact acataactag tctgacaacc ttctgaaacc gcccgttttt cagcagcttc
    25201 aagcaactga ccgcctaacc cttttcctcg gtattctttt gctacgcaaa atcgttccgg
    25261 cttgaagcaa gtaggtgttt tcttttcata acgcaaagta gctactggtc ttttttgatc
    25321 aagaaataga taataggttt gttgcgggat atcttttccg tcgaattcta gttctgcagg
    25381 aatcccttgt tctaatacaa aaacttgata tctcaaaaag cagctagctg cgcgtatcca
    25441 ttcatccgct ccaactattt ttttcatcat attcctcctt gtcatgaata gcagagatgt
    25501 attgattcct ttattcttat cgtaccaaaa atcgtggagt atgaccaaaa ggaaatgaaa
    25561 ataaaaattg agatattgac agtgatcaat agaatgcgta tactaaataa gtacgaaaag
    25621 gatatgattt gttttttaag actcacagaa aattctttct tggctgaaaa aagaatagtc
    25681 actaatcaaa ttgctccctt tttctatttt ggtagaaata ccgacgcagc tcagcgttat
    25741 cgagtttaag aggtaatgat tacacatcat tgcaatcaag gtggtaccgc gagttttcgt
    25801 ccttggctgt gatggtgttt ttttgtattt aatttataga aagcaggtaa tgacatgaaa
    25861 caattaagta gtgcacaagt tcgacaaatg tttcttgatt tcttccaatc taaaggacat
    25921 acgattgaac ctagtgcgtc tttgatcccc gtgaacgatc caaccttatt gtggatcaac
    25981 tctggtgttg caacattgaa aaaatatttt gatggttcag ttgtgccaga aaatccaaga
    26041 atcacaaatg cccaaaaatc tattcgaaca aatgatatcg aaaatgtcgg taaaacagca
    26101 cggcaccata cgatgtttga gatgctgggt aatttttcga ttggtgacta tttcaaaaat
    26161 gaagccatcc actgggcatg ggaatttttg actgatccaa aatggatggc attcgatcca
    26221 gaaaaacttt atgtaacagt ttatccaaaa gatacagaag caaaacgcat ctggcatgaa
    26281 gaagttggcc tgccactaga tcacattatt gatgtagaag acaacttctg ggatatcggt
    26341 gcaggcccat gtggtccgga tacggaaatt ttctatgacc gtggagaagc ttataacgat
    26401 ttagcagaag acgatcctga aaactatcca ggaggagaaa atgaacgtta tttagaaatc
    26461 tggaacttag tattttcaga attcaaccat aagcctgata acacatttga accacttcct
    26521 cataaaaaca ttgatacggg gatgggattg gaacgcatgg tctcaatcgt tcaagatgcg
    26581 tcaacgaact ttgagacaga cttgtttatg cctattatcc acgccgtaga aaagctaagc
    26641 aaacaagtaa aatatggtga aaacccagta acagatattt cttacaaagt aatcgcagat
    26701 catattcgcg ccctttcatt tgctattggc gacggtgcat tgccatcgaa tgaagggaga
    26761 gggtatgtct tacgccgttt gcttcgtcgt gctgtcatgc atgggaaaaa attaggtatt
    26821 gaacaagcat tcttatatcg tttagtccct gttgttgggg aaatcatggt aagttattat
    26881 cctgaagtac ttcaacaaaa agaatttatt gaaaaagtta tccgtacaga agaagaacgt
    26941 ttcaatgaaa caatcaatga aggtttggaa atcttaaatc aagtgatcca agaagtaaaa
    27001 aacgaaaacg ggacgactct agcaggaaaa gacatcttca aactatacga cacatatggc
    27061 ttcccggtag aattaacgga agaggtggca gaagatgaag gactgaaagt tgatcatgct
    27121 ggttttgaaa aagaaatgga tgcacaacgc gaacgtgctc gctctgcccg cagtactgaa
    27181 aaatcaatgg gggtacaatc tgctttattg acagatatca aagtagaaag taaattcatt
    27241 ggatacacag aacaagaatc agatagtcaa ttattggtca tcgttaaagg tgagtctctt
    27301 ttgaatgaag tcgcagaagg tgaagctcaa atgatctttg atcaaacacc tttctatgca
    27361 gaaatgggtg ggcaagtagc ggatcaagga tggatcatga atgaagtagg cgaaatcgta
    27421 gcagttgtta cagatgttca aaaagcgcct aatggtcaat ttatgcacac cgtagaagta
    27481 aaagcaccaa tgagtgaagg acaaacctat catctattga tcgatcaatc gatgcgcaat
    27541 cggatcatca aaaaccatac agcaacccat ctactgcaca aggcattgaa agaagtactt
    27601 ggcgagcatg caaatcaagc tggttcttta gtcgctcctg gacatttacg attcgacttt
    27661 acccactttg gtcaaatcac ttcagatgaa ttagctgaaa tggaaagaat cgtcaacgaa
    27721 aaaatctggg aagctatccc agttgaaaca attgaaacag atatcgatac agccaaaaac
    27781 atgggtgcaa tggctttgtt tggtgaaaaa tacggacatg acgttcgagt agtaaatatt
    27841 ggcggctggt caatcgaact gtgcggaggc acacatgtag caaatacaga aaacatcgga
    27901 atcttcaaaa tcgtttctga atcaggaatt ggtgcaggcg tgcgacgaat cgaggctgta
    27961 acaagtaaag aagcgtacga actacttgaa gaagaagaaa aacaactaaa acaagtagca
    28021 acaattgtta aatcacctca attgaaagaa gttgtttcaa aagcggaaca attgcaacag
    28081 caagtaagag agctacaaaa ggaaaatgaa caattagcta gcaagttagc gaatcaacaa
    28141 gctggtgatg tattcaaaga tccagaaacg atcaatggaa aaacaatcat tgcagcacaa
    28201 gtaaaagtga aagatatgaa tcagctgcgt caattagctg accaatggaa acaaaaaaat
    28261 atttcagata ttcttgtttt agcaaacgaa caagaaggaa aagtcagtct gctagcggca
    28321 atgacgaaag aatcaaatga agctggacta aaagctggcg acttgattaa agcaatcgca
    28381 ccgaaagtag gcggtggcgg tggtggacgt ccagacatgg cacaagctgg cgggaaaaat
    28441 cctgctggta ttccagatgc acttaaagct gcgaaagaat gggttgcgca acaatagggc
    28501 gtttacgttt gacagaaaaa caaaagttca aacattgaac gaaacatgat tatgggggcg
    28561 aagacaaaca agtcttgccc tcatactttt ttcaattgga tggcgcatct aatcaaatgg
    28621 tcggattcgg atggtcttta gttgacgaaa gtgacagaaa tttttacgat tagtataaat
    28681 aaaaaggggt gaaaaaatga atagtagaaa taagaccttt cgactagtct tacgtgcgat
    28741 cttgttagca atcatcatcg tacaagcgat ggttccttgg ctggggttta ttccattagg
    28801 attcattagt ttaacaatta tccatatcac agtaattatt gctgcagtag tattaggccc
    28861 aaaagatggc atggtgattg gcttgttttg gggaatcgct acaattgttc gtgcctatgc
    28921 catgccaaca acgccatttg atacattagt gttcacgaat ccgattatct cggtagttcc
    28981 cagagtactt gttggcttag tagcaggctt ggttttccac tggatttatc aaaaaaataa
    29041 atcaataacg atcagctcag cctttgcagg ggtactgggt tcattggtca atacagtctt
    29101 agtgttagga ttcatgggat tattttatac aggtgcaacg gcagatgcct atggtgtaga
    29161 ctctgctctt ttatttaaaa ccttagcagg ggttgcagca atcaatggga taccagaagc
    29221 aataggtgcg ggaatcataa caccattact agcaaaagcg ttatttgcag caacaccgtt
    29281 gaaaccagaa taatgaccat cttttaatag taataggacg cacgatagat agaaaaagga
    29341 agagaggaga ggaaaacaat cgtcctctcc atctttttac ctgagcaaca agcaaactag
    29401 aaggggtaaa aaacttggct aagaaacaag aagaaaaaaa gaaacaaata ccgcaacagc
    29461 ggacaaaaaa aggagtacta gcgggtatct taggattggt tacgaatctg atcttgtttg
    29521 tctctaagct aatgatcggg cttttttcag gaagtgtctc cattatggct gatgcagtga
    29581 acagtctatc agatactgct tcatccatat tgactttgat cggatttaaa attgctgcaa
    29641 agccagcaga tcaggaacat ccttatggac acgaacgctt cgaatatatc agtgggttat
    29701 ttgtttcgat catcattact tatgtaggat ttcaattttt agagtcttct gctgaaaaaa
    29761 tcatccatcc agaaaatgtc tctttaacac ccatcgtctt ttttgtccta atcatttcca
    29821 tctttttgaa atttgcacaa ggcaaaatgt atcaggttat tgcgcaatcc attgattctg
    29881 aaacattgag agctacagca acagatagtt ataatgatgt ctttactaca ctggctgtat
    29941 tgctttcagc agcaatcgaa tgggtaactg gatggcgtat tgatggatat ataggttttg
    30001 ctttagcatt atatatcctt tatagtggat tgacgatgct tcgaaatttt gtatacgaac
    30061 tattaggaag tcgcccaacg ccagcagaga ttgaagaaat ggaagagcat ttaaatgctt
    30121 gcgatgatat acttggctat catgatttat tggtgcataa ctatggaccc aataaacgct
    30181 ttgcatcagt ccacatcgaa gtagatgaat caatgaattt gaatgtggct cataagatta
    30241 ttgatctgat agaaaaagac tttaaaaagt ctttggatgt ggaacttgtc tgtcacttgg
    30301 atccaatgcc tgttgataac gaaaaatact ataatatctt gcggcagtta aagcaaattc
    30361 ttcttgaaac aggtacaggg cttaatattc atgattttag agtaattcat caaggaaaaa
    30421 cgctgcaatt tgatgtagtg gtccctgaga aattccagtt tgttgataca gaactagaaa
    30481 gaatcttacg tagtcaaata gaagaaaaaa tcggagatta ccaattggaa attacgtttg
    30541 atcacaatta tcttttatat taaatgagaa actataaaaa gactccttaa agtttttaat
    30601 ttaaagagtc tttttttctt ttaattgttt atggagagcc tgacgtgcaa gattatctgc
    30661 tcctttattt ttgttttcgg gcaaccattg caggatcaat aaagaaaatt cggatagaag
    30721 ttcttggatt ctttgaaggt agggaaggaa gagctcgttc ttcgttgcgt ttttgtcgac
    30781 cgtagaaact agtgttttgc tgtctgaaaa acagaaaatc gtttcattct gtaagtcgtt
    30841 tttctttaga aattctaaag tttttaaaaa gacttcgaac tctgcttgat ggtttgtccc
    30901 tatagaaagc gggatagata gctgttcttg tttaccttga tagacaatca agattccacc
    30961 tccactagga ccagggttgc cttttgtaga ggcatcaatg tatactttta acataaaaag
    31021 agattctcct ttttgttcaa actaatgtta tggtaagatt atatcattac tgaatcggtg
    31081 agaggttaga gaatgaaaaa aaatattcga tggcagcctg aactggcaca tacgatcatc
    31141 tattggtcat tgaccttgat cattctgttt tttagtctga ttctttcttt agaaaacaca
    31201 ggtccttatt ggaaaagcaa ttttgtttta ggtatttttc ttgtttttct atttctaggt
    31261 ttgcggcgtt cttttatttt aaaatcaaac tctgtgatta tacgttatgc tgctttttgg
    31321 aaagaccgag aaatatctgt cggacagatt cgatctttga cgccaactaa tactggggtg
    31381 caaatgatgt tgcaagatga gaaagcccca tctgttttca tgatgcgaaa aaaagatcaa
    31441 gtagtccttt ttgatcattt tgaaaaaaac ggacccaaat cagaatcaat tccttatcct
    31501 tatacgaaaa aaagaaaaag ctaattttaa aaatcagaac ctaaaaaaac gaatttttac
    31561 aggaaaagaa aagagtgaga cgtacggttc atcccgttta gcgtctcact ctatttgttt
    31621 atctattcat gcatactagt atcggtagtc tgaacgttgc ctttcttgac atgggcagct
    31681 tgtgttcctc gattcccttc gatgatctca aattcgacca cttgattttc ttccaaagtt
    31741 ttgaatccct cttcttcaat cgcagtaaaa tgtacaaaaa tttcttctgt gtcatcataa
    31801 ctgataaagc cgtatccttt tttgttgtca aaccatttta caattcctgt ggtcaaagca
    31861 ctcacgacct ttctaaagtc tgatcatagc cttcattata aagagtattt ataagtacgt
    31921 caaataaatt aaaaacctgt aattttatgt tttttttctg aataaaaaaa ggtataattg
    31981 gcatatctta acaaagaaga tattttgttg aataaagttc gtgaaaaggg gtaatcaaat
    32041 gaagaatgat ctgcaaattt cacaagaaac agagctagaa ccgattgttg aagtggctag
    32101 taaattagat cttaaggaag acgatttgga actgtatggg aaatataagg cgaaaatcaa
    32161 tttttctgga atcaatcgat caaaggataa cgctgagggg catttgatct tagttacttc
    32221 catcaatcca acaccagctg gcgaaggaaa gtcaacgatc actgtagggt taggagacgc
    32281 gctcaataaa atcaataaaa aatctgttat tgcattgcga gaaccctcac ttggtcctgt
    32341 gatgggaatc aaaggtggtg ctgcaggcgg aggatatgca caggtattgc ctatggaaga
    32401 tatcaacttg cattttactg gtgacatgca tgctatcaca acagctaata atgcattatc
    32461 tgctctttta gataatcata ttcatcaagg aaatgaattg aacatcgatg cccgccgagt
    32521 gatttggaaa cgggtagtcg atctcaatga tcgtgaactg cgtaaagtaa ttgttggctt
    32581 gggtgggcca atccaaggtg ttccaagaga agatgggttt gatatcacag ttgccagcga
    32641 aatcatggct atcttgtgtc ttgcggcaga ccttgaagat ttaaaggctc gtcttgcaag
    32701 gatcgttgtc ggctatacat ttgaccgtca gcctgtgact gctggagact tgaaagcaga
    32761 aggcgctctg gcattactgc tgaaagatgc aatcaagccg aatcttgtac aaacaattta
    32821 cggaacacca gcttttgtcc acgggggacc gtttgccaat atcgctcatg gctgcaatag
    32881 tattttagct accaagacag cattgagatt agcagattac gttgtcacag aggcaggatt
    32941 tggtgcagat cttggcggag agaaattttt agatatcaaa gtacctaact tgaaaaaagc
    33001 gccggatgct gtggtgattg tcgccactgt ccgtgcattg aaaatgcatg gcggaatgaa
    33061 aaaagatgaa cttaaaaatg agaatcttga tgctttgaaa gtaggttttg caaatttaaa
    33121 gcgccatata cgtaatatgg aacaatatca gctacctgtg atcgtcgcaa tcaatgaatt
    33181 cgtaacagat acagacaatg aactcacact gttggagcac ttgtgtgaaa atcaggggat
    33241 tcttgccaag agagcgagtg tatgggcaga tggagcagaa ggcggcgttg atttagcaaa
    33301 agctgtagta cgattgattg atagaaaaga agctaattac aagccattat accgcctaga
    33361 agaaacgata caagaaaaga cagaaacaat cgtcaagaaa atttacggag gaaatggtgt
    33421 tgttttcagc aaaaaagcgc aaaaacaaat agaagagttt acgaagaatg gatgggacaa
    33481 actgccgatt tgtatggcaa aaacacagta ttcattttct gatgatcctt cactgctagg
    33541 tgcaccggaa gatttcacca tcacgatccg cgaaatcatc ccaaaattag gggcaggatt
    33601 tttagtagcc ttgactggag atgttatgac gatgcctggt ttgcctaaaa aacctgctgc
    33661 attgaatatg gacgtgacaa atgacggaga agtgttggga ttgttttaag cttgattata
    33721 atctaccatc gaaggagctg tattttgact acagcttctt tttttagacg atagggaatt
    33781 aattttgttt acactaggat cattcttttt ctttattgta ttttgagcta tactaaagca
    33841 taataggagg gtatgatgaa aacgacattt ataagaaaaa ccggttttta cggtatgggt
    33901 agctcgattc agctaagaat caacaatgaa aaacgcagtg ttctcagtca tgaacaaaag
    33961 ataacgcttg atctggaagt gccctttacg atgcaggtca ccttttattg gctaaaaagc
    34021 cccgtttata cagtgaaaga agcaaagcct gcttatgtga tcacaatgaa ttacttgatt
    34081 cttcaaatct atccgttttt atttctagca actgggttgg gggccgtttt cctacaaaat
    34141 ttatttttca gtttttttgc agttattgtg ttgattgcgt tctttttcta tataaaaaac
    34201 cgggcatatt tgatcaagga ggaaaattat ggcaaactct gatctttttt taatcagttt
    34261 caatcgaatc gaaaaatgga tgagagacga gatgggaaat gcacgaaata tgggatttac
    34321 cgaacttgtc agacgcctag ctcaaagaaa acaattaatg atcagaaaat acgaagatga
    34381 tcttttacag cttgctcagt taaggaatgc gatcgtccat gatcggatcg cagtcgattt
    34441 tgtcattgca gagccaaatg attggacagt caagcgaatc cagctgatcg aacaagaact
    34501 gattcagcct gaaaccgtgc tgcctcgatt tgcaaaacgt gtaacaggtt ttgaacaaga
    34561 tcttccgtta cttgaactgt taaagatagt agcagaaaaa aggtattcac aatttccgtt
    34621 atacaataaa ggaaaatttg tagcattgat tactttacgt aatatcgggt tttggctagc
    34681 aaaagaaagc caaaaaggtc cggttgattt aacaaataaa cgagcgttgg atttgatcat
    34741 ccaaaacgga aagtacacaa attatcattt tgttccagct aaaacacata tttacgaggt
    34801 tgaagcgatg tttcgtgagc aagggacttt ggaagccgta cttatcacta aagatgggaa
    34861 tcccgatggt aatctgctcg ggatcgtacg acctcgtgat atttataaac aaatagaaaa
    34921 ggattgattt tttgttaatt atttattgga tattcagcgc tttgctagta ggagtggatc
    34981 agttggtcaa atggtggatc actgataatc tagcgcttgg agagacgaaa aatcttatac
    35041 caggtatttt gtcactgaat catattcgaa acactggagc cgcatggagt atgctagaag
    35101 ggaagatgtg gttctttact atagtgacac tcattgcagt cgttgtgatt ctcacattga
    35161 tgattaaaaa tcgtgaaaaa ggtaatcgct ggttcatgat tggattgagt ttgattctag
    35221 ctggtgcgat tggcaatttt atcgaccgta ttcgtcttgg ctatgtagta gatatgttcc
    35281 agacagattt tatgagcttt ccgattttta acgtagcaga tgtgacactt gtatgtggag
    35341 tgatttgtat gttaatttat attattttag atgaaaagga tcaaagaaaa aaatgacaga
    35401 acttaaaacg acgattcacc atgaatctgg taggatcgat aaagtattga ctaatttatt
    35461 caccgattac agtcgttcgc aaattcagct gtggctgaaa aatggagcgg tttctgtcaa
    35521 tggacagcca gtcaaagcaa attacaaagt aaaacaagga gacgagatta ctgtcttgat
    35581 ccccgaacca gaaacattag atgtggtccc agaaaatatc ccgttgacga tcgtttacga
    35641 agatgaagat gtagcggtga taaacaaacc tcaaggaatg gtcgttcatc cttcagcagg
    35701 tcatacgcat ggcacaatgg tcaatgcgct gatgtaccat atcaaggatc tttctacgat
    35761 caacggcgtt attcgtccag gtattgttca ccgaatcgac aaagatactt ccggactgct
    35821 aatggttgcc aaaaatgacc aggcacacga atcattagct cagcaattaa aagataagac
    35881 ctctttgcgc aaatatgttg ctttagtcca tggagagatt cctcacgaaa aaggaaccat
    35941 caatgcgcca atcggccgtt cgaaggaaaa ccggaaaatg caggcgataa gagaagatgg
    36001 gaagtcggct gtcacacatt ttactgtatt ggaacgtttc gaaggattta ctctggttga
    36061 attaaaacta gaaaccggaa gaacacacca gatccgtgtg catatgaagt atatcggtta
    36121 tccgttagct ggagatccag tatacggacc gaagaaaact ttgaaaggca atggtcagtt
    36181 tctccatgcg caaatgttag gttttacgca cccgactaca aacgaaaaga tgatctttga
    36241 agcacctctt ccagaagttt ttgaaaaaac tttagaaaaa ttaagaaaaa acattgcatt
    36301 ttaatttaga taacggtata gtaattaaca acgaaagcat aaaacttaat agaattcctt
    36361 taagtttagt cccgtgaggc taagaagggt gggagcaagg atacgtatgg tgcgccataa
    36421 gtagattgct cattgacata gtatagctat cagtgtatca gtatacgctc agtctaaaca
    36481 ttcctcctgt cctcttaggg caggagtttt tttatgcaaa aaagtagggg gaatgaaaat
    36541 gcaagcaaaa gaagtagtag atcaggtaac catgaagcga gcattgactc gaattactta
    36601 tgagattatc gagagaaacc atagtatcca agatatcgta ttggtaggta tcaaaacacg
    36661 aggaatctac attgcatcaa gaattgccga acgcctgaag cagctagaag atatcgatat
    36721 tcctgtagga gaactggata tcactttata ccgagatgac aaaaaagaaa atccagaaga
    36781 accggaactt cattcttctg acatcccagt ttccttagaa ggaaaagaag ttattttgat
    36841 tgatgatgtt ttgtatacag gacgaacgat tcgagcagca atggacgcag taatggattt
    36901 tggcagacca agaaaaattt cattagcagt cctggtcgat cgtgggcatc gagaattgcc
    36961 aatccgtgca gattatgttg ggaagaacat tccaacatct cgggcggaag agattttagt
    37021 agagatgcaa gagcttgatg gacaagatcg catcatgatt ttgaaagagg aagattagag
    37081 gagagagaaa catgtcggag aaaaaaggat ttcataatga tgacgtggtg ttagatatcc
    37141 acgatcgccc aaccccagga cattgggtag gattaagttt acaacacttg ttcacgatgt
    37201 tcggagcaac cgtgttagtc cccatcttag taggtatcga tccaggtatt gcgctagtca
    37261 gttcaggact aggtacattg gtgtacttat ttactactaa aggaaagata cctgcgtact
    37321 taggaagcag cttcgctttc attgcagcga tgcagctttt gatgaaaaca gatggttatc
    37381 cagcgattgc acaaggagca gtcacaactg gattagtcta tttgattgtt gcgctgatca
    37441 tcaaaaagat cggttcagca tggctggata aaatcttgcc tccaatcgtc gtcggtccag
    37501 tcatcatggt tatcgggttg ggacttgcgg caaatgcagc aacaaatgct atgtataatc
    37561 agggcacgta tgatttcaag tatattgctg tagcgctgat cacattagga ttaacaattt
    37621 tcttcaacat gtggctaaga ggttttctcg gattgattcc gattttacta ggtattatta
    37681 gcggatacat cgtagccttg ctgtttggaa tcgtggatac taagccaatc gtagacgctg
    37741 cctggtttgc tgttcctaac tttgagattc cctttgtaca atatgaacca aagctatatc
    37801 ttggagcaat cacaacaatg gcacccatcg cttttgtgac gatgacagag catatcggcc
    37861 atcttatggt attgaataaa ctaactaaac gtaatttctt tgaagaaccg ggtcttcata
    37921 agacgttgac aggtgatgga ttagcacaaa tcgtggcagc ctttgtcgga ggtcctcctg
    37981 taacaagtta cggtgaaaac attggtgttc tggctatcac acgtgtccat agcgtgtttg
    38041 tgatcggtgg agctgcagta tttgcagtca ttttaggatt cgtaggaaaa ttaagcgctt
    38101 tgattttaag tatccctgga ccagtcatct caggaatcag ttttatctta tttggagtaa
    38161 ttgccgcaag tggaatgaag attttaatcg agaacaaaat cgattttgat aaaaagaaaa
    38221 atctgttgat tgcttcagtt atcttagtag taggaattgg cggactcgtc tttgaagtag
    38281 gcacatttac attgtcggca atggcattag caactgtact tggcatcatt ttaaatctta
    38341 tcttaccaga aacttcacga agcgaagaaa actaaggagg aaacattatg atcatcaaat
    38401 cagaacgtat cagcttaaag catttattga ccgttgaggc acttactgat caagaagtta
    38461 tgggcttgat ccgcagaggg caggaattca agcaaggtgc taattggact ccgcaaaagc
    38521 gccagtactt tgctacaaac ctctttttcg aaaatagtac tcgcacacat aaaagcttcg
    38581 atgtagcgga gaaaaaacta gggctagaag tgattgaatt tgaagcaagc acaagctctg
    38641 tccaaaaagg ggaaacacta tacgatacag tactgacgat gtcagcatta ggcgtagacg
    38701 tagcggttat ccgtcatggt gatgagaact attatgacga actgatacaa agtaaaacaa
    38761 tccagtgttc gattatcaat ggaggagacg gaagcggaca gcatccaacc caatgcttgc
    38821 ttgatttgat gaccatttat gaagaatttg gtcattttga aggtctgaaa gttgccatcg
    38881 taggtgatat cactcactct cgcgtagcta aatccaatat gcagatgtta aaacgtctag
    38941 gcgcacaagt attcttctca ggtcctagag aatggtacga cgatgaattc gaagtgtacg
    39001 gacattatat gccattggat gaactactag atcaagttga tgtcatgatg atgcttcggg
    39061 tgcaacacga acgccatgat ggaaaagaaa gtttctcaaa agaaggctac catcaggaac
    39121 atgggttaac agttgagcgt gcgaagaagt tgcaaaaaca tgcaatcatt atgcacccag
    39181 caccagttaa ccgtgatgta gaattagctg attcattagt ggaaggatta cagtcgcgga
    39241 tcgttcagca aatgagcaat ggagtattcg tcagaatggc aatcttagaa gcagtgctaa
    39301 atggaaaagc gtaattatag gaggatgaaa aaatgaaaac actcattaaa aacggtcaga
    39361 tcaatacacg aaaaaatatg acgacaccag cagaaatttg gatagaagat gggcgaatca
    39421 aagcaatcgg tacaggattc tcagaagccg aatttgatga agtgtttgat gcaaagggac
    39481 aattgatcac acctggttta gtggacgtcc atgttcattt gagagagcca ggatttacat
    39541 acaaggagac gatcgaagct gggactcgct cagctgctcg tggcggtttc actactgtat
    39601 gcgcgatgcc gaatttaaat cctgtacctg atacggcaga aaagctgaga caagtatatg
    39661 acatcattag aaaagatgca gttgtgaagg tattgcagta tgcgccaatc acagaaaatc
    39721 tgcgaagtga gaaattagtt gatcaagaag cactgattga agaaggtgct tttgctttca
    39781 caaatgacgg tgtaggtgtc caaacagctg ggacgatgta tctggctatg aaagaagctg
    39841 caaaaaacaa taaagcccta gtagcccata cagaagatga atctttatta tttggcggcg
    39901 ttatgcacgc tggcaagaag gcagaagaac ttggtcttcc cgggatctta agcgtaaccg
    39961 agtcttctca aattgctaga gatctgttgc tagctgaagc aactggtgtt cattaccatg
    40021 tttgccatgt ttctactaaa gaaagtgtcc gtgtaatcag agacgcaaaa aaagcaggaa
    40081 tccacgtaac agcagaagtt tcaccccatc atcttatttt gatcgacgaa gatattcccg
    40141 aagatttcgg cttttggaaa atgaacccgc cgctaagagg acgggaggac agagaagctt
    40201 tgatcgaagg cttgcttgac ggtacgatcg attgcatcgc tacagaccat gccccccatg
    40261 gattagaaga aaaaagccaa agtttcatga aatcaccatt tggtatcgta ggaagcgaaa
    40321 cagcgtttca actgatctat actcattttg tagaaactgg tcgattcacg ttggaacaag
    40381 tgatcaattg gttggcagtt aaaccggctg agatttttgg tttgaatgca ggaacgctaa
    40441 cggttggtgc ccccgctgat gtagcagttt ttgatattac acaaacttgc acgatcgata
    40501 aagaagactt tttatcaaaa ggggagaata caccttttat cggctggaaa gtaaaaggcg
    40561 aaacacaaat gacttttgtc aacggaaaac ttgtgtggca gaagggagaa taaaagtatg
    40621 gaacgtttgc ttatattaga agatggaaca gttttcgaag gaaaggcttt tggtgcagat
    40681 gctagtgtct tcggagaaat cgtttttaca acaagtatga ctggttatca agaaactatc
    40741 actgatcaaa gttttaacgg tcaaatcatt acatttacct atcctatggt gggtaattat
    40801 ggggtaaata gagatgatta tgaatcgatt tctccaacat gcaaaggagt agtagtaaaa
    40861 gaacatgcac gtgtagcttc aaactggcga aaccaaatga cgctagattc atttttgaaa
    40921 caaaaaggaa ttcctggaat atcaggtatc gatacgcgcg cccttactcg caaaatccgt
    40981 gaagtcggaa cgatgaaagc tagtatagtt gatgctggag attccttcga acatgcattt
    41041 gatcagctga aagcaaccgt tctagcaacc aatcaagtgc agcaagtctc aactaacaaa
    41101 ccttatccaa gtccaggaac aggtcggaaa gtcattgtca ttgacttcgg cttgaaacat
    41161 agtattttac gagaattgag taaaagaaac tgtaacctca cagtacttcc ctataacaca
    41221 gatgccgaga cgattttagc gctatcacca gacggagtca tgctgacgaa tggacctggt
    41281 gatccaaaag atgtgccaga agcaatcgaa atgatcaaaa aaatccaagg aaaagtaccg
    41341 atttttggta tttgtctcgg tcaccagtta tttgctttag ccaacggtgc agatacctat
    41401 aaaatgaaat tcggacatcg aggattaaat cacccggtac gagaagtagc gaccggaaga
    41461 attgatttta cttctcaaaa tcatggctat gcagtcgatg aagccacgat tgatccagaa
    41521 aaactcatcg taactcatgt agaagtaaat gacggaacag tagaaggagt caaacacaga
    41581 gattatcccg ctttcagtgt gcagtttcat ccagatgctg cccctggtcc gcatgatgca
    41641 ctacatttat ttgatgaatt tatggaaatg atggacgcag gaaaggagca gtaaacagat
    41701 gccgaaacgt acagatatca agaaaattat ggtgattgga tctggtccga tcatcattgg
    41761 tcaagccgca gaatttgact acgcaggaac acaagcctgc cttgccttaa aagaagaagg
    41821 atatgaagtg gttttagtaa attctaatcc tgcgacgatc atgacggata aagaagtggc
    41881 agatcaagta tatatcgaac cgatcacact tgaatttgta tcaaggattc ttcgaaaaga
    41941 gcgtccagat gctctccttc caactttagg cggacagaca ggcctcaata tggcaatgga
    42001 gctggcagca tcaggtattt tagaagaatt gaacatagaa cttctaggaa caaagctttc
    42061 tgcgatcgat caagcagaag atcgtgatct attcaaacag ttgatgaaag aattgaatca
    42121 gccaatcccc gagtctgaaa tcgtcaatac agtagaagaa gctgtagatt ttgcaaataa
    42181 aatcggctat cctgtcatcg ttcgtccagc ctttacttta ggcggaactg gtggaggtat
    42241 gtgtgaaaat gaagaagaat tacgtatcgt atcagaaaat ggattaagtc tttcccccgc
    42301 tacccaatgt ttgattgaac gaagtattgc aggttttaaa gaaattgaat atgaagtgat
    42361 gagagattcg gctgataatg caatcgttgt ctgcaatatg gaaaattttg acccggtggg
    42421 tatccataca ggtgattcta tcgtatttgc ccctagtcaa acattgtctg accatgaata
    42481 tcaaatgctt cgtgatgctt ctctttcgat tattcgagca cttaagatcg agggaggctg
    42541 taatgtccaa ctcgctcttg atccacatag ttttaattat tatgtgattg aagtcaatcc
    42601 gcgtgtttct cgttcatctg cgttagcaag taaggcgact ggctatccga tcgctaagct
    42661 agctgctaaa atagcgcttg gattaacatt agacgaaatg aaaaatcctg ttacaggaac
    42721 gacttttgca gaatttgaac ctgcattaga ttatgttgta gctaaaattc ctcgctggcc
    42781 gtttgataag tttgaaaacg gagaacggct tttaggcacg cagatgaaag caactggtga
    42841 agtgatggct atcggtcgga atatcgaaga gtctttattg aaagctgtgc gttctttaga
    42901 aatcggtaca caccatatcg aacttcctga gttggcagac atcacggacg atgacctaat
    42961 ccaaaaagtg gttcgagcac aagatgatcg cctgttttat gtagctgaag ctattagaag
    43021 agggtacacc atagaagaat tagcggattt gacaaaaatc gatttattct ttttagataa
    43081 actgttgcat atcgtagaaa tcgaacagca gttgaaacag cagccgttgg atgacaagat
    43141 attgaaaaca gcgaaacaaa acggttttac agacaaaaaa gtggcggagc tgtgggaaat
    43201 aaacgaagaa gccgttcgcc agatgagaaa agaaaatgat ttgattcctg tatataagat
    43261 ggttgacact tgtgcagcgg aattcgaatc aaaaacacct tatttttata gttcctatga
    43321 atatgaaaat gaaagttcac gatcagaaaa gccctcaatt ctagtactgg gatctggtcc
    43381 tatccgtatc ggacaagggg ttgaatttga ctatgcgact gtgcattctg tcaaagcaat
    43441 ccagcaggca ggatacgaag caatcatcat gaacagcaat cctgaaacag tttcgactga
    43501 cttttctatt tcggataaat tatattttga gccattgacc ttcgaagatg tgatgaatgt
    43561 gatcgagcta gaacagccga taggagtaat cgttcaattt ggtggtcaga cagcaatcaa
    43621 cttagccgaa cctttgactg ctgctggtgt aaaaatctta gggacaacga tcgaagactt
    43681 ggatcgtgcg gaaaatcgtg atttattcga gcaagcgctg aaagagttgg atattcctca
    43741 acctttaggg gatactgcta caagtaaaga agaagccgtg gttatcgctt cgagaattgg
    43801 ttatccagtt cttgttcgtc caagctatgt attaggcgga cgtgcgatgg aaatcgttga
    43861 aaaccagcga gatttagaag attacatgga acatgctgtg aaagcatctc cagaacatcc
    43921 agtactagtg gaccgttact tgcttggtgg tgaatgcgaa gtggatgcga tttgtgacgg
    43981 tgaaacagta ctcatcccag ggatcatgga gcatattgag cgtgctggtg tccattcagg
    44041 ggattcaatg gctgtgtatc cacctcaaac attatctgaa tcgatcaaga aaacgatcga
    44101 agattacacg atccgcttag cattaggttt gaattgtgtc gggatgatga atatccagtt
    44161 tgtcatccat gaaaatgagg tttatgtgat cgaagtcaat cctcgagcaa gtcggactgt
    44221 tccattctta agtaaggtga caggaattcc aatggcacaa attgcgacga aagctatttt
    44281 gggagagaaa ctaaagacac ttggttatga aaacggactt tatccagaaa caaaagaagt
    44341 tcatgttaaa gcacctgtct tttcttttac gaaattgcag aaagttgata cttacttagg
    44401 gcctgaaatg aaatcgactg gagaagtaat gggatctgac agacaattag acaaagcttt
    44461 gtacaaggca ttcgaagctt ctggattaca cttgcctgaa tatggagccg tattatttac
    44521 gattgcggac gaaacaaaag aagaagcact agaattagct aaacgtttta cagaaattgg
    44581 ctatagtctg ataggaacga aacatacagc tgcttatttc gaaaaaaatg gtctggtcgt
    44641 tgaaacagta gcgaaaattt ctgaggaagc agcagaaaaa aatgtagtcg acttaataag
    44701 agatggtaaa acacaagtgg ttgtcaatac gattgataaa gatcggggaa atgcttctaa
    44761 agacggtttc atcatccgaa gagaagcagt tgaacatggt attccattgt ttacttcttt
    44821 agacacagca gatgcgatcg ttcgagtgat ggaatcccgt gctttttcaa ctaaccctat
    44881 ttaacggcga gcacatgtta agacaaaaag acgaaaaacc gttgcaggag gggacagatg
    44941 aaacaagaaa tgatggaaat cgttcagcaa aaacagctgg caccaaagat ttttgaaatg
    45001 acattgaaag gtgatctagt aaaagaaatg cagcaaccag gacagttctt gcatattctc
    45061 gtgccgcgtg cagacttgct attacgccga ccgattagct tgaatcatat cgaccacgaa
    45121 acaaatactt gccgtatcat ttatcgggtg gaaggtgagg ggactagagt cttctctact
    45181 ctttctgccg gagaccattt agatgtcatg ggtcctttag gcaatggttt tgatttgtcc
    45241 aatcttcata caggagacga agtatttata atcggtggag gaatcggtgt ccctcctcta
    45301 tatgagttat caaaacagtt agtcgaaaaa ggaattaagc caacgcattt tttaggtttt
    45361 gccacacatg aagtcgttta ttatgaaaaa gaatttaatc gtctaggaga aacaagaatc
    45421 gctactgacg atggaacata cggtatgcac ggaaatgtcg gtaatttatt gttaggaacg
    45481 aagacggaac ctacagctgt ttttgcatgt ggttcaaacg ggttattgaa gacagtggaa
    45541 cagctgtttt cttcgcatca aaatgtccag ttatcattag aatcccgcat ggcatgtggg
    45601 ataggggctt gctatgcttg cgtttgtcat acgccggaag atgaaacagg aacaaaaagt
    45661 gtgaaagttt gtgacgaagg accgattttt aaaataggag aggtaattat atgaatgaga
    45721 atcctttagc ggtcaaactt cctggcctag aattaaaaaa tcctatcatg ccggcaagcg
    45781 gctgtttcgg ttttggcaaa gaatacggaa aatactatga tttgaatcag cttggatcga
    45841 tcatggtcaa ggcaacgact ccaaatgccc gctttggcaa tcccacgcca agagtggcgg
    45901 aaacaccatc tggcatgttg aatgcaattg gtttgcaaaa tcctggtcta gacgttgtta
    45961 tgcataaact tcttccagaa ttagaggagt acaatgagtt acccatcatc gcaaatgttg
    46021 ctggtgcttg tgaagaagac tatgtagaag tttgtagcaa aattggcgaa gcaccaaatg
    46081 tgaaagcaat cgagctgaac atttcttgcc caaatgtcaa acatggcgga attgcttttg
    46141 gaacagattc tgatgttgct tttcaattaa cacaagcagt aaagaaagtt tcttctgttc
    46201 ctgtctatgt caaattgtcc ccaaatgtaa cagacatcgt tccaatcgct caggcaatcg
    46261 aagctggagg ggcagatggg tttacgatga tcaatactct tcttggtatg cggattgacc
    46321 ttaagacaag aaaaccgatt ttagccaatc aaacaggtgg actctccgga ccagcaatca
    46381 agcctgtcgc tattcgtttg attcaccaag tagcaagtat atccagcctt ccaatcattg
    46441 ggatgggcgg cgtgcagaca gtggatgatg ttcttgagat gtttatggct ggagcaagtg
    46501 ctgtagctat agggaccgcg aatttcaccg atccgtatat ctgtcctaaa ctaattaaag
    46561 agctccctgt gcgaatgagc gaactaggca tcgaatcgct ggaaagatta atcaaagaag
    46621 tgagagagga acgtgaacga tgaatcaact agaccaacga ccaattattg cattagattt
    46681 ttcaactagg caagaggtag aagactttct tcgatttttc ccgaaagaag aaaaattgtt
    46741 tgtgaaaatc ggaatggaat tgttctacca agaaggacct gaaatcgtac gttatctaaa
    46801 agaggctggt cataatgtat ttttagatct gaaacttcac gatattccga atacggtcga
    46861 aaaagcaatg cggggattgg caaagcttgg tgttgatctc acctgtgttc atgccgctgg
    46921 cggtattcgt atgatggagg cggcaatgcg aggattagaa gaggggactc cagaaggtgg
    46981 aaaacgtccg ctacttctag ctatcactca gcttacttct acaagtgaag aagaaatgca
    47041 tgccgatcaa ctaatcgaag tttctttaga aaaaagtgtg atccattatg ctagctgtgc
    47101 caaaaaagca ggattagatg gtgtggtttc ttctgcttgg gaagtagaag cgatcaaaga
    47161 aatggcagga gacgaatttg tttgcttaac tccgggtata agaccagaag gaacagtcgc
    47221 aggagatcag acaagagtag tcacaccttc tcaggcaaaa aagatcggct caacttttat
    47281 cgttataggt cgaccaatca ctcagtcaac taatccttat aaagcatatc aaacgattca
    47341 aacagaatgg agctaaccta aaatgaatgt tgaacaaagt atcgcaaaag acttattaga
    47401 aattgaagca gtatttttaa atccaagtaa tccttttaca tgggcaagtg gaatcaaaag
    47461 cccaatttac tgtgataacc gaatcacgat gagctatcca aaagtccgaa aagagatcgc
    47521 aaaaggatta gcaagcaaaa tcaaagaagc ttaccctgaa gtacaagtga ttgctggaac
    47581 tgcaacagca ggaatccctc atgccgcatg ggtagcggaa atactggatt tgccaatggt
    47641 ctatattcga agtaaggcga aagatcatgg gaaaggtaac caaatcgaag gacgtatatt
    47701 tgaaggtcag aagatggttg tgatcgagga tttgatttct acaggcggaa gtgtcttgga
    47761 agcagctgaa gcagcaaaaa gagaaggtgc ggatatcctt ggtgttgcgg ctatctttac
    47821 gtatgagttg ccaaaaggaa aagcaaattt cgaaaaagcc gaaatccctc ttatgacgtt
    47881 gaccaattat tctgtattga ttgaagcagc tttagaagat cgttatatcg atgagcaaga
    47941 attaactctg ctaaaagaat ggaaaaaaga tcctgaaaat tggcagattt aagcgcgctt
    48001 gatgaagata gagaaatccg atttgtgtct ccagaatcat caattggaat agcaaaaatc
    48061 caaaaactga ttgcgagaag catcttttca tcaggtatga aaagaaactt ctatcgtgat
    48121 cagtttttga tttttttaaa attcattttt ctaagactgg ttagcagaaa gaagagaata
    48181 atctcttctc ttttttctat tatatataga ttttctctat tttttggtaa gggagctgtt
    48241 tcaaaaatgg taaagagcgg aaatgttgcg aatatcagtt atttaatgat atgatattcg
    48301 taaaaagaaa tctcaaaggg aggtaacttt tatggggttg aatgaattta ttttaggatt
    48361 gaacaattta gagacgatca caagggcacc tggatttttt aaatatacag agcatacagt
    48421 tgcagcacat tcgtatcgtg tagcatctat tgcgcaagtt ctaggagaca ttgaagaagc
    48481 gaatggacaa ccgatcgatt ggaaactgct ctatgaaaaa tcattgaatc atgactacac
    48541 agagcgtttt attggtgata tcaaaacgcc ggtgaaatac gcaagcaaag agttaagagg
    48601 gatgctgcaa acagttgaag aaaagatgac ggacgaattc atcaaccaag agattccagc
    48661 tgagttccaa gaagtttatc gccgtcggtt gttcgaagga aaagatgaaa ccgtagaagg
    48721 agaactatta gccatttcag ataaggttga ccttctttat gaatcttttg atgaaatcat
    48781 caaaaataac ccggaaaaag tttataagga gatgttcatt gaggcagtga ctacgattaa
    48841 aagctttgaa catcggcctt ctgttcagta tttctttaaa gagatatttc cggaactatt
    48901 gaaccaggaa ttttatggaa aagaggcgtt tttagaaacc gtctcaacga ttgtaaagaa
    48961 agaagaaaaa taaaaatgat atgagatgca gggggaagta tagttgaaaa agaatatgga
    49021 tgtcgaatgg ggctattctg gagacaaagg tccggaaaat tgggcgagtt tatgtgattg
    49081 gtttgcgaga ggtgcggaat ttccattgca gtcgcctatt catttgacca agggggaaga
    49141 aaccaaaata gaaggagaca cgctttcctt tcattatcaa aagcaacggt ttactgacaa
    49201 ggaattcaaa aacacgattc atttagtacc ttttgaccaa ctcagttatg tagagttcaa
    49261 gaaagaacgc tattatttga cagatattca tttccacttg ccttctgaac atatcatcaa
    49321 cggaaaacag gaagatattg aatttcattt tgttcatatg aacagcaaaa aagagaatct
    49381 agttgtgggt gtcatgtacc agctaatggt acaggaaggt tggctgtata atcaagaaaa
    49441 tggggaaagt tggaacttag aaaaacatga gcattgggta aatccggatg tgttctttcc
    49501 ggagcaaaaa agccatttcc attatattgg ctcattgaca actccgccta ccagcgggcc
    49561 aatccaatgg tttgtaatgg atcatgtagg aaaactgaac caagagtttc ttctcccctt
    49621 cgatggtcag tatgctcgac cgaacaaccg accaatccag cccttgaatg gaagagaaat
    49681 ttattatttc gaggagtttg agcaatgaat attcagcaga tgaaatacgt ggtcgctgta
    49741 gcaaacaatg gtagtttcag agaagcggca aagaaaatgt ttgtctccca gccaagtctt
    49801 tcagctggta tcaaagaatt agaaaccgag ttagggatca cgctgtttac tcgaacgaat
    49861 cgaggggcat atttaacaga agaagggcaa gacttcttaa atcgtgccga gaaaatattg
    49921 gtccagcttg atacattaga aactcactat ctaacgagtg aaaagagaga caatttttcg
    49981 atcgctgccc agcattatga tttcttaggt cctttgaccg cacagctact cgaggaattc
    50041 aaagacgaga tcaaacaatt tcggatcatg gagacgacaa cagcgagagt gatcgaagaa
    50101 gtcaaagagc agcacagtga gatcggcatt atttatatga atgagcataa tcaagctggt
    50161 atcagaagat atttacaaca aggagagcta agtggccgca gcattggaaa attcaaaacg
    50221 catatttttt taaggcaagg acatccatta gctgaacacg cagagatcac caaagaagaa
    50281 ttgttatctt atcctcaagt tcgttttaca caggatggaa ataatttccc gtatttttat
    50341 gaagacctta tcgagatccc tgatcaagaa acagtgattt atacgagtga tcgaggtact
    50401 ttgatgaata tcgttcttga aactgatgct tacgcttcag gatctggtat tgtgattgga
    50461 gggattcgcg agcacttgcg gttaatccct ttggcagaag gcgaactaaa tgaattttat
    50521 atcatttatt cggcgaaacg tccgctcagt gaaatcgctc aaagatttat caaagagctt
    50581 actcggttac tggaccagca gagctaagaa aagcagatga gaacgctgtt tattgaacac
    50641 cgttgatcaa aaaagagggg ttgtgacaga attttgtcac aactcctctt tttgtagcaa
    50701 acaatttata actaattgct gttgtgggaa agtacgcaaa tatgattcta gaaacactca
    50761 ttgattacct gttttgtttc atagctgtaa ttttttcttc ttctggtgtc acgataatcg
    50821 tcttttggtt ttcataaata acataaccag gcttggcgcc atttggtttt cggatatgct
    50881 ttacctgtac aagatcaacc ggcacttggg cagagtatcg gtattttgaa aaataggcag
    50941 ctaactcggc agcttctgta attgtttcat ctgagggctt gtcactttta atgatgacgt
    51001 gcgaaccggg tatatttttt gcatgaagcc aatagtcggt ttttttagct gtcttcattg
    51061 tcagctggtc attttgaaga ttgtttttac caacaagaat gagcgttccg tcagaagaaa
    51121 agtattgatc aggctgagat ggtttcttac gtttttgttt ttttaagttc ttctttttca
    51181 ggtatccttc tgaagtcaat tcttctttaa ttgcttcgat atccattggg ccggcaattt
    51241 ccagttgaga taagacagat tcaagatatt ggatttcatc tttggcttct tggatttgtt
    51301 cgccaatcag cttaacagcg ttcttcagct tttggtatcg atggaaatat ttctgtgcat
    51361 tttgatttgg tgtcaatgcc ggatctagtg ctattttgat tggccgatct tcttcataat
    51421 aattaggtaa aacaacttct tttgcgccgc gtggtacttg tgtcagaaaa gtagtaagta
    51481 gttcgccatt tctacggtaa ttctcagcgt tttcggattc tttgagtgtt tgttcacgtt
    51541 ttttcaattt atttttattt cgttttagtt cattttcgat ttttcgaatc agttctccgc
    51601 cttgttgttt tgcccgatct ttctctgctt tttcgtgata atagctatct aataattgac
    51661 tgagtgttgg ataagctgtt acagcagatg cctgttcgga caatacctga taagcaatcg
    51721 gtgtgaaaaa atctttattt tccgtttcgt aaaaagtagg aataggctga tggctgatgg
    51781 ctgagaaaaa ttcgtcccat acaaccatct tttcattagg acgttccagt aatcttttgg
    51841 tcagctcttg agcgatatcg aaaccgattc cctgaaactg acgttggatt gcttttggat
    51901 ctagttcagt ttgggaaagc cgctgaaaga ttttttcttt ctcggagcta aatgggttca
    51961 agacctcttg ttttggcgga gcaacatatt ctacaccagg aagcaaagaa cgataagtgt
    52021 tttgagagct tccaatgtgt ttgatcgcat ccagtatttt tccagtttct cgattaacta
    52081 agacgatcgt actatgacgt cccattaatt caacgatcaa tatgatattt tgtagatcac
    52141 ccaactcgtt tcgtttagca aagtggaaat ggatcactcg atcattttcg atttgttcga
    52201 tgtcttctaa aatagcgcca tccaaatatt ttcgaagcat catcacgaag ttaggcggat
    52261 tatcaggatt ctgataatcg atttgggtaa tctgtacacg agcataactt gggtgcgcag
    52321 ataataataa tcgatggttt ttgccgcgtg aacgaatcac cagcacgatt tcattttcat
    52381 aaggctgatg gattttcgag atccggccag atagtaacgt ttcacgcaat tcgttgacca
    52441 tcgcgtgggt aaatacacca tcaaaggaca tggttcattc ctcatttctt ttcataagta
    52501 tattcattat aacgaaaaaa agaagaaaaa ccaatttggc cgaatagtaa agcaaaagtc
    52561 tagaaaaatc ttggactaat tacataaaaa acagtgtttc tatcgttgaa atccaaattt
    52621 ttaggtataa taaaaaatag gagaaaaagt agaaaagaag gtgtttgtta tttgggaagt
    52681 agttaaatcg agagtacaag aaatgaatga acatttctca gtgtcattcg cagaaaatcc
    52741 aagtaagtat tttcgacgtc ttgtttttct gctcatctta tcattgctgt taacagttgc
    52801 aatgttttta ttgccggaaa aaatccgaga agagcaagta aatagtctcg tttattcgtc
    52861 cataccaacc agcaaattga aaccttttga ttacagcaaa gctgatcaga aaatcaaaca
    52921 aagccgggcg atatcggtga tgttcagcaa accgaacggg aaaacctatc aggacatgct
    52981 tgatgttttt aatgatcctg agcttatgga agaattgaat cgaccgatct tttattatcc
    53041 gatcgtttat gatgtacatg aactggaaca aaaatataac atacgaacgg atgaagtgac
    53101 atttattttc tttgatggag gaaaagaagc aaatcggata actgcgggta agggaggaat
    53161 aactgatttt gataaggagt tgatccctga actgaatcga cttccgttag ccaatatcaa
    53221 acaattagaa gaagaattgg atagaacggg agtaacttcc caaaattccg agattgctaa
    53281 ttgagacatt ggcgcgatga aacggtgggt ctatatagcg ctatttttaa ttatcagaac
    53341 aagtgatgtt tgatcttcaa aataacaaat aaaaaattaa aaaatatagt tgacgaaatt
    53401 caaaaattcg atttgactta aatcaattct taaggaaagg gtgacctgta atgaacttat
    53461 caaaacgtat ttcagcagaa aacaaaaaaa attggcgcag ctggcgtaga taagttgtat
    53521 taatggtgag actttcccat agatacaact ttttagagtg catttctaaa gcttgtatct
    53581 atgctagaca tgaacattga ctgccgcata gattagaatc tatgcggttt tttgtgtaaa
    53641 gacaatgacc gctttggcca ttgtcttttt ttgtagactg gatacttgcc tgattataat
    53701 aaataaaaag attgactttg caggaggaaa aaaatgaaaa acaaacgatt aataacagtt
    53761 gtagtaatta ttttagttta tttagcaggt gcatttattt atggaaaagc ctcaggcgaa
    53821 aaagaaagta cttcgacgaa ccagacaaaa aaaacaacag ttgttggggt attgcaatac
    53881 gtgagccatc cggcattaga tgagatttat cgaggaatca aagatggtct gaaagaagaa
    53941 ggattaaaag aaggagaaaa tcttgagatc aaatttcaaa atggacaagc cgatcagagc
    54001 aagctagcca caatgagtca acagctagta caatctgatc cagatgcctt gattggaatc
    54061 gcaacacctg ccgctcaatc attagcaaac acgacttcat cgatcccagt tgtgttaggt
    54121 gctgtaacgg atcctgtggg ggctggatta gtcgcttctt tagagaaacc tggtggtaat
    54181 gtaacaggtg tttctgatca gccgcctgtt acttcacaaa tcaagcttgc ttctgatttg
    54241 ttgccaaatg caaaaaaagt cggaatcttg tatgcttctt cagaggataa ttcaaaatac
    54301 caagtagcac aagcagaaga agctgcaaaa aaagaagggt tagaatcagt aaaatatgcg
    54361 gtgccttcca ctaatgagat tgcacaaacg gttcaagtga tgagccgaca agtcgatttt
    54421 atctatgttc cattagataa taccattgcc aatgcgatgc aaacagtggt aaaagaagca
    54481 aacaaagcaa atatccccgt cattccatct gtggatacaa tggtggaaca aggtggacta
    54541 gcaacaatcg ggatcaatca atatcaatta gggcttcaaa gcggtaagat ggcggcagaa
    54601 cttgcgagtg gaaaagaaaa accggaaacg acgcctgttt atacatttga tcaaggggat
    54661 acagtgatca atcaatctca agctgatcgc ttaggaatca ttgttcccca atcgatgaag
    54721 gaaaaagcca aaatcattac agatgactcg cagcaagaaa catctaagga ggatgacaaa
    54781 tgatcgtatc agctatttca caaggcatgc tttgggcaat attaggatta gggattttca
    54841 tgacttatcg gatcttagac tttcctgata tgacgacaga agggtccttc ccattaggtg
    54901 ctgctgtctg tgtgacagct attactcatg gggtagcgcc gattgtagct acattattag
    54961 gcgtaggtgc tggcatgata gcaggactcg ttacggggtt actttataca aaaggaaaga
    55021 taccggttat tttagcaggg attttagtga tgtcaggatt gaactcagtt attttgtttg
    55081 tgatgcgaac accaaatctt tctttattga atcatccgat tctacaagac agcttccatc
    55141 gctttgggtt acctgattac tttgacacag tccttcttgg cttcatctct ttgggcatct
    55201 tgattgctgt actgctattc ttcttcaata cagatttggg tcaaggctat attgcgacag
    55261 gagacaacga aacgatggct cggtcgttag ggataaaaac cgatcgtatg aaaattttag
    55321 gtttaacttt gtcgaacggt gtcattgcat tatccggtgc gctgattgcc cagaacgacg
    55381 gatatgcaga tgtaaataaa gggattggcg taatcgtcat cggtcttgct tccatcatca
    55441 tcggtgaagt gatcttccaa gaattgacgc tagcagaaag attgattgct attgttgtcg
    55501 gcagtatcat ttatcagcta ttgattttag tagtaatcaa actagggttt gacacgactt
    55561 atctgaagtt gttctccgct atcatcttag ctatttgtct gatgatcccg caattgaaga
    55621 aagcactgaa cttaaaaacg ggttttgaga aggaggcata gtaatgactg atatattgac
    55681 aatcaaaaat ggcagaaaag tcgtaaacaa tggaatgaat gaagagaaag tactattgga
    55741 tgaaattaac cttacaatca gagaagggga cttcatcact gtccttggcg ggaatggtgc
    55801 tggaaaaagc acactgttca atacgatcgc tggtacgctt caactcagtc aaggatcgat
    55861 ctcttttaaa gatcagctga tcacaaaaga ttcagaagaa aaaagagcac gattcctttc
    55921 tcgagttttc caagacccca agatgggaac ggctcctcgg atgacagtag cagaaaattt
    55981 gctacttgca caaaaaagag gtcaaaaacg gaaattccgt ttacgtaact tgaaaaatca
    56041 aaaagaagat tttttcagac tatgtcaaga agtcggtaat ggcctagagc aacacttgga
    56101 tactccagcg ggtgaattat ctggtggtca acgccaagca ttaagcttgc tgatggcgac
    56161 gatcacagct cctgagttac tattattaga tgaacatact gcagctttag atcctaaaac
    56221 agctaaagca ttaatgcgat taacaaatca gcggatcaat gaacaaaaat tgacttgtct
    56281 catgatcacg catcgaatgg aagacgcctt gaaatacgga aatcgtctga tcgtactcca
    56341 aaaagggaaa atcgttcaag atatttctga aaaagaaaag caacatttga caatgggcga
    56401 ccttttgcag ttctttgaag aagtagtgga ttgatttcga cagaaaaatt cctttcagta
    56461 gaaggacttg aaaactcatt gacatcttcc tttgattcat cctatactta aaacaataaa
    56521 caattaaaca tatttgggtg ttttgtagga tcacgtagtc aatgatttta acaattaaat
    56581 agaatattct ttgctctgac aagtaaacga tgagaaaaga atttgctact ttgccaccta
    56641 gacgtttcgt actttttcgt atcaaacgct aagtggcttt ttttattgaa gtaagaacaa
    56701 aggaggaata agatgatttc tggacaaacc aaattagctg ggctctttgc tgatccggct
    56761 tctcacagtt tatccccatt gatgcacaat actgcttttg aagcaaacaa catcgatgcg
    56821 gtgtatttag ctttccaagt aaatccaatg aatttgaagc aagcagtcga aagtattcga
    56881 acttttgata tgttaggtgt aaatctttcg atgccgaata aaacagcggt tattccttat
    56941 ctggatgagg taagccagga agcgcaattg atcggagcag tgaatacgat cgtgcacgaa
    57001 aagggtcgtt tgattggcta taatactgat ggtgcgggct tcatgcaatc cgtgcaagaa
    57061 gctgggattt cgatcaaaaa gaaaaaaatg actctactgg gagctggagg tgcagcaaag
    57121 gcagtcactg ttcaagcagc gttagacggc gctgaggaaa tcgtagttta taaacgaaac
    57181 aaccaaacat tcgctcaagt aaaagaaaca ttcgaacaac tcagctatcg aacttcttgt
    57241 aagataaaag ttcgtgactt tgccgatacg catcaattaa gaaaagactt gaaagaaagc
    57301 tgtcttctag tcaatgcaac agatatcggg atgggaaaga aaatcaatca gtcaccgctc
    57361 ttagatataa gcatgatgca tgagaatcta gcggtttttg atttgattta tgcacctaga
    57421 gaaacacgtt tattaaaaga agcaaaaaaa gtaggagcaa aaggatacaa tggacttggc
    57481 atgttgatct accaaggagc aatcgcgttt gaattatgga caaaggaaaa gatgccgatc
    57541 catgtgattg aaaagctgtt tgattaaaaa aggataatag ataaagatct tttattctcg
    57601 cataaacggt ctcaagaaaa gtaatccttt atgtatcgaa gcatttattt cgttattttt
    57661 tattaaatta tcaaaaaatg ataggctttt gtcgattggt tatcgtatcc tttatttatc
    57721 agtaagaaac gaggaggaac cacaatgagt cggatggatc gctataagga catccataag
    57781 aaggcgaaac ctctgaagcg ggatacgggg agtatttttg ctagaagaga acgaaaacga
    57841 acgcgtatgg aaaatgagga agatgctacc cgtatttatg aaagagagca gcattcattt
    57901 gaacatttga accaatacga gcaacagata tacagagatg caccaagagc agaagaacaa
    57961 caaaaaaata aaaaattttt caatcggcaa aagaagaaca aaccgttaaa acctcgaaga
    58021 aagcgatcgt ggaaaaaaat cattctatcg attttgcttg ttttgatcct ttattcaggt
    58081 atctcatttt ttattggtaa atatgtagct gaacatgaca caagcttaga ggcagcgact
    58141 tcagaaacct ttcatgggca aaaagcgacg aatggtgcgc ataatatttt gatccttgga
    58201 agtgatacac gcggagaaga tgccgggcga gccgatacga tcatggtctt acagttggat
    58261 ggtccttccc ataagccgaa actgatttct tttatgcgtg acagcttcgt tacgatccca
    58321 ggggtaggac aaaataagat caattcagct tatgcatacg gaggagccga tctagtgcgt
    58381 caaactttag tagaaaattt tggaatcgat tgtcaatact atgcgaaagt cgatttcaaa
    58441 tcgtttgaaa aagtgatcga tgccttattc atgaacggag tgaagatcga tgcagaaaaa
    58501 gatctgaatc tggatggtgt agatattaaa aaagggggcc agaagatgga tggacatgtt
    58561 cttttgcagt acgcacgttt ccgaatggat gaacaaggag actttggccg tgtcagacgc
    58621 caacagcaag taatgaacgc tattttcagc caattgaaga atccattgaa tctgatccgt
    58681 gcaccttatg cagctggtaa agctttagga tatacatcca cagatgtcac tgcttggttc
    58741 ttgacgaaaa acctcttttc gattgcacga ggagctggtg gcattgatcg aataagtgtg
    58801 ccagtagacg gttcgtggaa ttatgggcaa agtgattatg ctggcagtat tcttgaaatt
    58861 gataatcaaa tgaatcaatc tgctattaca gattttttga ataaatgatc ataaaaaaga
    58921 tcaagaagaa gctgcgcaag gcttttgtca tgaatcaatc aaacgattca ctcgtaaaaa
    58981 acgctttctt atggtagatt taaccaagag aggagctgtt tacattggat atctatctga
    59041 acttcaaaaa tgagtcgcgt gaagccatcg ctttttatga aaaagttttt cagactgaag
    59101 catcaggtat caccacatac ggtgaaatgc ctggaataga acaaatgaac ttgccagaag
    59161 aagcaaaaaa tctaatcacg aatgcacggc tgaacattta tgatacatta gttatgtttg
    59221 cagatacgcc agaaggaatt ggtcctgaat tagttgtggg aaataatgtt tctttagtca
    59281 tccagacaag aaatgaagaa gaaacgaagc gcctatttga aagcttagct gagggtggta
    59341 agattgagat gccactggat gctgttccgt gggctcagtt gtatgggatg gtaactgatc
    59401 gatttggcat caactggcag attaaccaag agtgacagct aaagatgaat attttctgga
    59461 aacatcaagc agcaaacgga tcatcgtttg tttgcttgat gtttttgtgt ctatttcgac
    59521 tatacggtat ctttttttta ttgccagatg cgaaaatatg ttccataata gagaagtccg
    59581 caaaaaatta agtaacggag gtcagaagat gaagacggtg atactagctg aaaaaccttc
    59641 acaagcaaaa gcctatgccg aaaccttcca acagcaaaag cggcatgaag ggtattatga
    59701 aatcagcgat ccattgtttg ctggtgaagt aaccatcact tatggttttg gaaatttggt
    59761 agatatggtt gctccaggag cttatgaaga gcgttgggca aaatggtctt tagaaaattt
    59821 gcctattttc ccagaaacct tccgttacga agttccaatg gacaaacgtg cacaattttc
    59881 gatcgtaaaa cgagaattgc agtcagccga taccatcatt attgcaacag atggtgatcg
    59941 agaaggtgaa gccatcgcgt ggtcgattat tcgacaagca aacgcatttt ctaaggaaaa
    60001 gaactattta cgtttatgga tcaattctct tgaaaaagaa gcaatctatg aaggttttaa
    60061 gaatctccaa cctggaaaga actattttcc aaaatataaa gaagcgcaag caaggcagaa
    60121 cgctgattgg ctgattggaa tgaatggaag tccattatat agcttgctac ttcaacgaaa
    60181 agggattgat ggcagttttt ctcttggtcg tgtacaaaca ccgacactct atatgattta
    60241 tcagctgcaa gaagaaatca aacacttcaa aaaagaaacg tactttgaag gagaaggttt
    60301 aattacgaca aacaaagggc agttttctgg aaaaatcgta ccaaaaaaag catttaaaac
    60361 ccaagaagag ttaacgaagg aaatagaaaa acttggagcg catttaggta agcaaaacgg
    60421 acggattctt gaagttacga aaaaggaaaa gaggttgcat agtccacgtt tattttcgct
    60481 atctagtttg cagacaaaga tgaatcagct aatgaaagca agtgccaaag ctacacttga
    60541 tgctgctcaa ggattgtacg aaagcaagtt tctaagctat ccaagaacgg attcctttta
    60601 cattacagaa aatgagcatc agtatctggt taaacatctg caaaattata aaaaattttt
    60661 aggaatagaa gaagtacaga caactgagat caaagcaaag aaacgatatg tcgatgcgaa
    60721 aaaagttcaa gaacatcatg caattattcc gacaaagacg attccgactc ctgcacgctt
    60781 tgcgaagctt tccaaattac agcaagcaat ctatttgcaa gttttgcgca ctactgtggc
    60841 tatgtttgct gcagattata tctacgaaga gacgaccgta atgacgggcg tacagcaatt
    60901 aaagctaaaa agcatcggaa agatcccatt acagcaaggt tggcaggaaa tcttacgcat
    60961 caagtcaaaa aagaaagaag ctcagactct tcctcctatc gtagaaaatg aagaagcaga
    61021 agtagaactg aaaagtatgg agaaagaaac acaacctcca aaaccctata ccgaaggaac
    61081 gttgatcaca gcaatgaaaa ctgcgggaaa aacgctggat aatgatgaag cgcaagaaat
    61141 tctcaaagaa gtagaaggaa tagggacaga agctacacga gccaatatca ttgaaaatct
    61201 taagcagaag cattacatcg aagtcaataa aaacgaaata actgttacgc caaaaggaat
    61261 cactctttgt aaggcagtag ccaatgaacc attactgacg agcgcagaaa tgactgcgcg
    61321 ctgggaaggg tacttgagaa aaattggtaa acaagagggg acaccatctg tttttttaga
    61381 gaatatcaaa aaattcatcc tacatttatt ggcagaagtt cctaatcaaa tcgacaaggt
    61441 agacttttca gatgagatta gcgggacacg tcagataaaa gcgatggaga agaaaaacga
    61501 tcaattagga agatgtccaa aatgtaaaaa gggaatagtc atgctttatc ctaaaatcgc
    61561 tacatgcttg aatccggaat gcgacttcaa attgtggcca acagtagcta aaaagaagct
    61621 gactaaaacg aatctcagag atttgctttc aaaaggaaag acaagtaaag ttgtcaaagg
    61681 ttttactggt aaaaaaggga aattcgatgc agttttagta ttaaaagaag atatgacaat
    61741 cggtttttct tttccatgga tcgaaaacag tggaacaaaa gcagttgatg gaaacaaaga
    61801 aacatcaaga aaaaataatg aaaacgaagt agagtaaatg aaaacaatga aatagcggaa
    61861 tatttattcc gaaaagtgag aatataaata ccaataaaac taaaaaatat cagtgaatca
    61921 agcaaaaacg ttggggtagg ctgattttat atagatagca aggagttttt ttatttgaaa
    61981 aaagtgcatt catttttaaa ttatcttatg ggagcaatca cgattgtggc tgtgtaccaa
    62041 gcatttctaa agtatcctga ttacgggacg aagttgttgt cattgacgca caatcaaaca
    62101 gcatattcac caacgttgat tttatcgact ttgactgcag gagctaaaag cgctacttat
    62161 ttttttcata aaacgacaag catgctaaag cgaaagaaac agcgaaaaca attgttggtg
    62221 gtggtagcgg ctatgatcat tatttatttt ctaccagtta ttacacaagt atttcatcaa
    62281 tattttggtt aagaatacga gagtttgtga caaaagtcat gtcacaaact tttttctttg
    62341 tcattttttc gtaagaaaaa gcaaaataaa agtatataca ttgattaaaa gtatatactt
    62401 ggatataatg tacttactat agaatgagaa tggtatagag ggtggcgaaa tatgaaaaaa
    62461 atgaaaaagt ataaaattag aaaatctggc aatagcgatg taacaactat cccaccagaa
    62521 gtaaaagaat tcatgggtgt gcagacaggt gacgcaatca gttatgtttt tcaatctgat
    62581 ggttctgtac gaatgatcaa agcacaagaa gaacctgata ttgattcatt agttgattcg
    62641 atcatgaatc aatatgaaga cgcgttaaaa gatttggttg atttatgagg tatctttcga
    62701 ctaaagaaat tatcaaaatc aacgcgaaag ttattttacg tcactcgcca ggcgaaatga
    62761 tcggtgtaaa agatgcaaat gcattagata tggccgtcaa acagccttca caagcagtat
    62821 tcaatcaaga actctatcct gaaatctatg aaaaagcggc gattttagca attaatttag
    62881 ctaaaaaaca tccttttcat aatggcaata aacgaactgc tcttgttgcc atgttgttgt
    62941 ttcttcaatt gaataattgt ccagttgctt tttctcgtca agaagctgtt gattttatca
    63001 taatgattac cactagttca ttggatttcg attcactaaa gtccaagata accagttatt
    63061 tacgacaaac cgcaataaaa tgaacgaatt aaaaacttta tttctcaatt agatcagcat
    63121 gtcattaagg aatatgctga tttttttatg tttaatcata caaaatagtt ttttcataaa
    63181 aatatggaaa atatggatta attttgaaat aattgattta aaaggaatac aaaagagtga
    63241 atagtaggaa atagtggttt agaactagtg ggctgatttt ttatatattt tagtttacat
    63301 aatatatatt atacaaagta gatttaaaaa atgataaacc tctctcgaac ggttttttat
    63361 caaaaatcgt catttttcca tcaaaatctg cttatgcaaa attataaaaa aattttgcag
    63421 tttttcttac tttttttgtc gtttaattga atgataaaaa ccagtttctt tattcagtta
    63481 atcaaatatg aacgaattag atatgaatca ttgtatttgc cgttgcggaa ggatttttta
    63541 attaaccaca gataaacatt gataacgatt cgcttattgt aatcaacaga ttaaatttca
    63601 tatgttcata tgtacggata cattttcgga ccgattaatt ttaaccattc tgtttatttg
    63661 cttacctatt agatatcaat aaaaaactgc ttaacagcta tttcagctgt taagcagttt
    63721 taggattttt agttcatatt cattgtttct tataatacag tgttcaatac ttctcttaaa
    63781 gcacttgttg atttgctgaa cattgctttt tcttcttcgt tgattgataa ttcaacaact
    63841 tcacgaacac cattttcgtc aacgattgat ggcacacctg taaagatatc tttttcgtcg
    63901 tattcaccag ttaaataagc agatacaggc aatacagctt gttcgttatt caagatagct
    63961 tttacgatac gtgcagtact cataccaata ccatagtaag ttgctttttt acgatcaatg
    64021 atctcataag cagcattacg gactttatca gcaatcacat ctaattcatc ttgggcaata
    64081 cgatggtctt tttctacaat ttcaaacact ggtttaccac cgacagttgt atgtgaccat
    64141 gcagcaactt ctgaatcacc atgttcacct aagatatagc cgtggacgct gcgtgggtca
    64201 acttttaatt tcaatgcgat ttctttacgg aaacgagttg tatccaatgt tgttccagta
    64261 ccgataacac gtgatgttgg cagaccagat tcgttccaag cgatatatgt caaaatatct
    64321 actgggtttg aagcaacaac gataataccg tcgaatcctg atcccatgat ttcttttacg
    64381 atttggcgca tgattgacgc atttgtttta actaaatcta aacgagattg accaggtttt
    64441 tggttgatac cagctgtgat aacaacgata tcagcatctt tacattcttc atagccacct
    64501 gaccatacag ccacattttc atcgccccaa gccataccat ctaaaaggtc caatgcttcc
    64561 ccttctgctt tttcttgatt cacatcgatc aatactaatt cattagagat tccttggttg
    64621 atcattgcat aagcgatact tgttccaaca aaacctgtac cgacgattac tactttacga
    64681 cttgtttttt tcatgaataa acagctcctt ttcataacta tttgttactt tcatgaaaag
    64741 tatagtcttg tttattcatt ttatcaacat gttaattata atagttgtta ttataatttt
    64801 tgatggaaac gaattcctga atacgcataa cagataaatg acaaatgttt acacctatat
    64861 cccctgataa tacaaccaaa agtttagaac tgaaaataaa tccaaaaaaa ttcgctgcaa
    64921 cgatataata agacagcaat cgcacctaaa acaattttcc ttcatatgct ttagtgaaag
    64981 attttcttct taatgtttat ttctccattc attgggagta catgttgaat acttcttgaa
    65041 taatttgaat aaagaagtcg tttgtttata tccgatacga ttagcgattt cttccaacga
    65101 aaaactcgtt tcttgaatca gttccaacgc aaagtcgaat tttttcttta gaaccagttc
    65161 ttgaaaggaa gcatcaaaat acattttcaa tttattacta agatagaccg gattgtagcc
    65221 aaaatgagct gctgtttctt ttaacgtaca agaagtaaaa tgcttatcga tataatctaa
    65281 tactctaagc atctcatttt ctgcgcatcc atctgctgat gaaaagcttt gttgttctaa
    65341 taaatgagtc aattcgatca gtaatagtga tgtatagaga tttaacgaac ggatcttatg
    65401 actgtatgta tcaaaataaa tcaacagcat attttcaatc aaatgcgtca aacgacttgt
    65461 ttttccgccg cgaaaatgaa tgaattgtgt atgttcccct ttttcttttg atgcatttat
    65521 caaaaaagaa gaaagtagat tatttgtgct tgccaaatga ttcaatatct ctgtagataa
    65581 ggtttcttct tttaataaga tgttgattaa aatatcctct tgccctgtgt attcgattct
    65641 ttgagtagct tctttatcaa tgatcaccac gtcactttct tccatctcta tcctttctcc
    65701 attaataatt tgtaaacatg taccgctata catataattg atttcaacaa aatcatgtgt
    65761 atgctcggga acttccgcat atcgacggtg tttactgata tgaatatttc cctgttgaaa
    65821 tagatcccct cggtggattt ttggcggtgt ctgaagatgg taagctaagt ttaaatcatt
    65881 gatattcatt ccttgttcac gctgcagagt ttcgattgat tcttcgttac gcaaaaaaaa
    65941 tgtctaattc agctagttcc aattgactcc ctcctttttg taagcggttt ctttcgctta
    66001 ttagttcacg ctgtactgct attatatgca aagctatttt tggtttcata aagactttct
    66061 atggttggga catgaacttc ctgtgattcc gctattgaga gaataaccac ttcatactat
    66121 atttttgata agcgcttaca aaaatgaaag gaacatgctt atgaataaaa agatgatgaa
    66181 attttctctg ctgtcagtct ctcttatttt gacttctgct ggtgcagtca cgtctgcaat
    66241 tcccagtatg tcagctactt atgccacgcg ttctttatct gctgttgaat tattaacgac
    66301 tgctccctct tttatggtca ctatttttgt tttgattagt agttttattg ctaggaaaat
    66361 cggacaaaaa caaactgtga tcatcggatt agtgattgca tcgatttgtg gtatcctccc
    66421 cctcttctca caaagttaca gtattgtctt agcttcaaga gctggactag gtattggctt
    66481 tggattgatc aattctttgg cagtcagcat gattgctgcc ttttatcacg gagatgaacg
    66541 agcctctatg attggttttc aaagtgcatt tcaaggattt ggtgcagctt taatgacatt
    66601 tgttgcagga cagctagtac agttcggttg gcaatatacc tttttagtct acgccatcag
    66661 cttacctatt cttgtcttgt ttgttttgtt tgttcctaca cctgaaacaa ctgaacttca
    66721 atcgcatggc acagccccaa caagacaagt aatcaaaacg aatcctaaaa tgattagtta
    66781 tggtattttt ctcttgctgg tcatcgtggt atataatgct gtatcgatta aattagccac
    66841 agtcctgacg acttattctc taggaaacga aactaatgca gcgaatatct taacaatcat
    66901 gcaattggca agtatggctg ccggagtttg ttttggctgg cttcagacaa aagcacatcg
    66961 ctatatgctt acactttctt tactactgat gggaatcggc tttgtattga ttgccactgt
    67021 gataaacctg tatgtgattg ggtttggtgc gatcctaaca ggaatttctt tttcgttatt
    67081 cattccttac ttattcaacc aagtaagtat ccaagcgccc aagtacgcgg agagtttcaa
    67141 tacttcaatc ttattggttg gcgctaattt aggtactttc attgcaccat atggtttgct
    67201 ctttctctct tttgcttctc ttgggagtaa aacacttgct gttttcgtca atggcagtat
    67261 cttgctgttg attagcgcgc ttattagcct tctagtagta cacaggacga atagaaagac
    67321 agtgataaga gtagatgaag aaataaaaga acaattgaca acaaaataaa tttgatggag
    67381 gtcgtgtaaa atgacaaatg aaaaacataa agatagatgg ctttggtatc ctggagactt
    67441 tgagatccgc catggactgc tacaaaattt ccaacgggaa gaacgaggtt ttgactggcc
    67501 agcgtactgg tacatggatg attgccatcg gaacgtcaag tttaagagat attactttct
    67561 tgatcaacct tccatgttta aagtgacgat ccaaggagtt gggtatgtag aaattaatgg
    67621 acaaaaacat ccatgtggaa aatggctgac ttgtccagct ggtaaagcaa aaattcgtat
    67681 ctttgtagga catacatcag ggctaccagc gatgtttatc gagggagacg aagtaaaatc
    67741 agatattggc tggacagcaa gtaattttat tgaagaatat ccagctggct ggagtccgct
    67801 ttatgtcgat atcgcaaaag atccaaatca aatctattat caaaaagaat gcgtccatcc
    67861 agtcactgaa acggagattg gcggaggaat cttattcgat tttgggcgag cagtgaatgg
    67921 ctgtgtagaa ctaatatctc tggatgacca tatcgaatct atcactctat gttatggaga
    67981 gtccgatgta gaagctatgg atatcgatta ttgctactat aagcaaatag gaatgacaag
    68041 aaaaatgaaa gctcgtaaac gcgcttttcg ctatttgttt ataccagagg tttctactgg
    68101 aatggttcaa cttcaagttt ttcatgaatt tttatctctt tcgaaacaag ctgctttttc
    68161 aagcgattct tctttactga atcagatctg gtcagtatca gaagaagcct tcaagttatg
    68221 tagtgatttg ttttttatcg acggtatcaa acgagatcgc tggatttggt ctggagatgc
    68281 gtatcaatca ttcatgatca atcaatatct tttttttgac gaggaaatca ataaacgaac
    68341 gatattagca ttaagaggac aaaatgaaat caagcagcat atgaatacta tcgttgacta
    68401 ttcgatcttg tggttgattg gtatcgaaaa ccactatatg atgacgaaag actatgaatt
    68461 tttacgcatc gtctacccta agatgcaatc attaatgaga tacttgatgg agcaaacgaa
    68521 tgaattaggg tttatttatg ggagagcaaa agattggata tttattgatt ggtctgaaat
    68581 ggataaagaa ggaacgcttg ctgcagaaca agtcttatta ctgaaagcct atcattccat
    68641 gatcacttgc ggagatatct tagctgaaac atatggagag aacgaaaatt atcatactca
    68701 tctctatcaa gaaaaatatc aactattgaa acaaaaccta tttgactact tttgggatga
    68761 agaacttggc gcttttatcg attgctatga atctgggaga agaaatgtga cgcgtcatgc
    68821 gaatattttc gctgttttat tcgattttgc taacaaagac caacagcaat cgatcttaaa
    68881 gaatgtctta ttgaatgaca ctatcacaca gattactact ccatatttca aattctatga
    68941 acaagatgct ttatgcaaac tcggacagac gaatatcgtc taccaaacga ttcttgatta
    69001 ttggggaggg atgttatctc atgatgcggt aactttctgg gaagaatacg accctactca
    69061 aacaggaaat gaaaagtaca gtatgtatgg agatccttat ggaaaaagct tatgccatgc
    69121 atggggagca agcccaatct atcttttagg acgctatttt atcggtttgt atccaacaaa
    69181 gccaggttat gaagaattta tgatacaacc taatctagat tcatttgaaa cactgaattg
    69241 tacgctacct atcaaagatg gaaagatttc gcttgaaaaa acaaaagata agatcgtgat
    69301 tacttctgat agaacaggcg gaacagtgaa aatgaatggt aaaagttatc ctcttctagc
    69361 aaaacagcca cttgtcttaa caagctattc aaaaataaat gcataaaaca aaaaactgct
    69421 tgcgacatat cagaagactt taaatcttct tctgatattg tccaagcaat ttttattttg
    69481 aagtttgctt aattctgttc tttagaaaca atgtttgttc tttttccggc aaaaagaaag
    69541 ctagataata cgacaagtaa aaagaaagcg atgattccaa ctgtcaaggc tatttgaccg
    69601 tattctccta gtttcccaag tacaagtcct ggtactagat aatcagtatc ggcaaatgta
    69661 gaagaagcga ttttaagatc tcctaatact ggaaggataa ataatggcag ccaactaatc
    69721 aataagctat tgaaagcaga acctaatacc gcccctcttc taccgccagt cgagttgccg
    69781 aagacaccag aagcagctcc gcagaagaaa tgtcctacta ccccaggaat gataactgta
    69841 gtttgcaagc ctatcatagc aaacatggat agtgttccta caaagaagct aacaaaaaag
    69901 ccaattaata cagcattagg tgcatatgga aaaacgatag gaacatctaa tgctggttta
    69961 gaatcgggta cgagtttttt agcaatccct tggaatgctg gaacgatttc tgccaacacc
    70021 attcgaaccc cttgaaggac gataacaaac ccagctgtga atgttccagc ttggatcagt
    70081 gcaaagatta cagcgttgtc tccattgctt agttctcttt caacaaatcc aggaccagct
    70141 aacaaagcaa gtgcgacata tacgatcgac atcaagagca tgatcgatac agtagaatct
    70201 cgcaaaaagc tgaaactttt aggaatcttt atgtcctctg tagaacggtc tttgtttcca
    70261 aaaaactttc cgatccatcc actagaagca taaccgatat ttccggtatg ccctaacgca
    70321 acttgattgt ttccagtgat gttcttcata aacggttgac aaagagcagg cgtaatagtt
    70381 aatagtgttc cttcgaagac cccgcctaat aagatcatcc acaaatttgc agtaaacccc
    70441 gcgcttacta aaatgactgc tgttagacaa gaaacataaa gcattgcttg acctgtaaga
    70501 aaaatgaatt tatatcttgt gaatctagca agtaaaatat tcacgatcat ccctactagc
    70561 atgatcaaag cagtaggtgt accgtattgt tgcaaagcaa tcgccactac tgcttcattg
    70621 ctaggaacta ctccttgagt atgcagagct gtttggaaca tcgaagcaaa aggggttagt
    70681 gaattactga ttaaaccagc accgccgatc agtactagga atccgacaaa tgttttgata
    70741 gttccttgga tcacttctga aaatttcttc ttctgaagaa cgagaccaag cagtgcaatc
    70801 aaagaaacga ggatggaggg ctgactgacg attgacacaa acaaattcaa caatttatcc
    70861 attgatagtt cctcccttga atcattttta ttcttttgac aagatcttcg ttactttttc
    70921 ttttacttct tcgctgtcaa tgatcgattg caaaggtacg agcttttcat caggtataga
    70981 agttagcgta tctttcaaag aatgctcaat gaagaaataa tcagccatat cgctagatac
    71041 acttccaaca tccgtatgac ttacttcaaa ctcgtccaca tctgctccaa gatctgcaag
    71101 tgcttgtttg atgttcatct ctaccataaa acttgttcct aatccacttt gacatactgc
    71161 aaaaattttc atatcattcg tctccttttc ttatgatcgc taatatttct tcttttgttg
    71221 atgcgtgtaa taaatcttga agattttgtt tattagaaag tagctttgtt aaatttgcca
    71281 aagcccgaag atgtgcctca ttatcgatag cagctaaaca gatgaacaaa ctaatgggat
    71341 gggctggatt atcaagcaga tccacaggtt gttgaagttt cagcaaagac atccctactt
    71401 cgtttacgcc atcttctgga cgagcatgag gtaatgcgat gtgatcgcca atatggataa
    71461 acgcaccata ctgctccacg cgctcgatca tagctttgat ataactttct tctattttat
    71521 tttctgataa tagcggctgt gcggcaaatg tgattgcttc ttgccagttt tttggttgat
    71581 ccgataattg gatcatttct tctgttaata attcagatag cataggacgt tgatcctcct
    71641 tcttttctaa aagtttgttc attttacgat ttaatacttg atagagcttt tcttcgtcta
    71701 cgccttcttt taattcgata taaggcagta gcgccgacaa caattcttgg gcagaaggca
    71761 ttgaaaatcc tggtatcagc caatctcttt gtacttgatt gatcagctga tttttttcca
    71821 agtcagtcat gattggatgc agaacataga gagacttttt cttatcagta agtgtgagag
    71881 gtacagtaga aaaaataata tcgtaagaag tttcgtcaac ctcgtgtaag cggtcagctg
    71941 aattagtctc tgtaaaaaag atcatcggga ataattgctg aagttcactt tttaagatca
    72001 atgaagagct aatgccactt ggacagacga tcacggctct tatttttcta tttctttctt
    72061 ctgcgtccgc ttttctgatc tctccgccaa atagtatagt gaaaaaacca atctcttctt
    72121 cagggatgct cttccctatt cgtctttcta acggaagtaa tgcttttctt gtcatttcgt
    72181 agatggaagc atattgatgc ttaatttgat cgatcatcac attaggtaaa taaaaagaat
    72241 aggaaatacg aaaataggca gggaccaagt gataaaagac attcatcaat aattcacgaa
    72301 acgaagcaaa ttctacggcc atcaggaatt ccatgcgatg gatgacttct gaagaacatt
    72361 ccagcaaaaa atcaagtgca ggctcctgga catctccttc aacgatcgat gctaagcaaa
    72421 gagagaaaaa tataatctcc gaattttgat gttcggaata gccaaggcca gtcaatactt
    72481 gtcgactaat gtcagtgact gcaagagaag ccaacagttc agcatctttt accagttcca
    72541 tggatgtttt tccaattcga atggttgtca aactcaaata ataagctaat tcatccattc
    72601 gatttggtgc gaatcgaaga tctgatagtg aaatcgtttt atctagcaaa tctctaactt
    72661 tggcgtaata atcaatggaa agggttgcgg ttaaatacgt gagcccaaat cttccagcaa
    72721 gtgactgcat caaacgagca gtgcgatttt ttgcttctct tcttaatatt gcttctgacc
    72781 ctagcagcct aaaaccagtt ttcctagtat acgacagctg acaatcttcc acttctaatt
    72841 catttcttat ctttttgata tctgacagga ctgtcccttt agaaacctga agaaaatctt
    72901 gaaaatgaaa aacagaaaca gacgttgcag tcgaataaac catcaaataa agaagatctc
    72961 ttcgctcttg ttcggtatac acagcttcaa atcgagtaat atccaaaaat ttttctgccc
    73021 agtcgattgc tcggaatttc tttatacgga tacgggtatc atccacatat tcggcaaaag
    73081 gagttaattg tttgatcgcc tcgcttgtat ttacttcgat gatctctgct gctttttcta
    73141 gactgatttc tcttggtgtt ttcaggagat aactaatttt gtagttcaca gcgctgttca
    73201 cctcctactt atattctagt atggtagcgc ttttaaatcg aggggtgttt ggtacaactt
    73261 acagttggat tttttttacg actgtaccga acgatttcta tcgaatggat acagaaaaaa
    73321 agcaggtgac caaatgtctc ctgcttttat gaattgattt cgtccgatca atgatgatca
    73381 tgtttatttt ttgaggtcag ttcttcaaat ttttctttga catcttcaac cgctttttcg
    73441 atatcttttt caaagtgatt gggctcatta ggctttgttt cctcttctac agaatttgaa
    73501 ccagataaag ctgtttcttt attttctgtt tcaccagagt ttgtgccagc taatgattct
    73561 tctttgtctt ctgtttcacc agaattagtt cctgctaaag ccacttcttc ttctgtttta
    73621 ggggccattg aacctcttaa tcgtttgtgt ttttcaccgt cataatttgt catgttggtt
    73681 cctcctagta gttctatact ttttcatcgt acaataagac agtttatgcg tcaaaaaaca
    73741 aacccgattc ttacaaatat gtcatatttt tccttctgat tcttgaatgc ttttgattcc
    73801 ttcttccaaa attttcattt gtaagattgt ttcttcatct ttgatgactt tttctgcgcc
    73861 attaactaat gtctcgtaaa tcccttcgta gacacggctg taatcaccaa cctcggaaat
    73921 tactttttct tcatgataac tcccttgttc atctatatag gtcaatacac cataatgttc
    73981 gggcaaatcg ataccaaagt cttcatgatc aggcatgtaa aacattttca gatgttcttc
    74041 ttgtcgatct tttgtttgtt tcacgaacat cccttttttt ccgtaaacga cgaaacttgg
    74101 acgttctttg atgcggaaat aactggattt tatcgaaatt ttcatatttc catagaaaaa
    74161 atccagatcg aagtaatcat tcattcgtcc tttccctaaa agttgacgta catcatagct
    74221 gatatcatct ggttcgccga aataagaaag aacttgatct actgtatgac aagcatgtcc
    74281 atataaatag ctgttcgcag tagaaaattc atgcgtattt tctggtactt ccggtctgaa
    74341 ataatcataa tgcatttcta cttctaaaat atcccctaat tttccgcttt cgattacttt
    74401 ttggactgtc aagaagtcag aatcgaaccg tctgttttgg taacattgga taaatagacc
    74461 tttttctttt gctaatgcaa ataactcttc tgcttccttt gacgtttctg caaaaggttt
    74521 ctctactagt acattcttac catgttcgag tgccattttt ccatattcat aatgaaattg
    74581 actaggtgta gtgatgacaa ctaattggat ctcaggatca tcccaaagat cagacagctg
    74641 atcagtatat tcgatgtctt cgaatgtttt ccacactggt tcagatgggg aaaaaatttt
    74701 tttgatattg attttgttcg taagttttct tgaaaaaggc aaatgatagc gatttgtact
    74761 ctttccattg ccaagataag cgattgtaag catgagtggt gcctcctttt attgatgttt
    74821 tcagtatatc ctagaaaagc gcagaaagta tttataatag ctattctggt aaaaaagttc
    74881 agaaaaacac ttgttatcat tcggtttggt gaaattaatg ttcaaagtaa ggataaaaat
    74941 caaaaagata gtagcggaac caagtgttta tcagtaagat agaatttgga ggtcagatca
    75001 tgcttattga agaaaaacta acaaaacaag agttgtttac cacgacagag aaacggattg
    75061 tcgattacat ccgtaggaat atcgaagctg cagtctacat gacgattgaa gaattagcaa
    75121 aagctacgta tacttcccat tcagctatca ttcgtttatg caaaaaaatg ggattcagcg
    75181 gatttaaaga attccgtttc gagctggggc gggaagttca tcaattgatt gctcagttca
    75241 atcaaacgat tgatcctaat tttccttttt caagtgaaga tagcactcag caaattgcaa
    75301 agaaaatggc ggatttatcg atccagtcaa taaaaaaagc acaattgcag attgaacatg
    75361 aagatttaga tcaaatcggt aaagtattga acaaggcaca gcgaatcttt ctttttgcaa
    75421 aaggtgattc tcaaatcacg gcaaggaaat tccagaataa aatggtcaag ttgaataagt
    75481 ttttgatcat ggctgaagaa tacagtgatt cttcttggaa tgcagccaat ttgactagcg
    75541 aggattgcgc catttttatt agctacagcg gtcgcatcca tcattatgaa cgaataatga
    75601 cctatttgaa gcatgtagag gcccctacct tgctgattac cggaaatcag cattcagaaa
    75661 tggccaaaca ggctgatatg tgtcttgtta tatcgcagga ggaatatgat tttgctaaag
    75721 tagcgacttt ctcctctcaa attgccttcg attacgtatt aaatacgtta ttctcagtga
    75781 tatattctca aaattttgaa gagaatatcc gcaacttgaa aaacaaacaa gaattgatgc
    75841 aaaaaggcct tcttaaagaa tatcggaaaa cttaagaaaa gatcctcatt tagtaataag
    75901 aaagatagtg tttgataggc tctctttgat atcatcataa aaacaggctg aagttttctt
    75961 tttcaaacct cagcctgttt gtttacggaa cgattcgaat agatatatta tagaaatgag
    76021 gaatagctaa cttctgtttc ttattttgaa cgattgacga aaaagatata taagaaggag
    76081 gaaaatcagt atacatgcag ctaacaatcc atacaggaaa aatcgtttgt tctcggatac
    76141 tttctgtact tctttttgaa cttcttttgc atgataagga acccggtgcc ctctgacaag
    76201 taagcgatga ctgttgacca tataaggtgt acaagttagg agtgtcacga aatcctgccc
    76261 tttttcgatt ctcagatctt ttgtatcagt cggttctacc gtcttgatct gatcgacttg
    76321 ataagcgagt gtccgtccat tgatttcgat atagaaagaa tcacctaaag tcagtttcgg
    76381 taagtctgtg aacaactttg cttgaggcag tcctcgatgg ctggaaataa cggcatgtgt
    76441 attttctccc cccgtaggat aagacgttcc ttccaataat gaggcacctt tttctagcag
    76501 cacagtattc gtttcatcaa aaattggcaa atggacattg atctcaggga tcgtcaaaat
    76561 accgatcgta tgtttctcaa aataggttct atcctttttc gcaggttctt ttttcttagt
    76621 aaagggatct gcacctggat ttccaccttc ttttgctaat tgctggtttt tctttgtcat
    76681 gttttcttgg attttagcca tgacttcttc attttctttg accgcttgtt gctgataatg
    76741 agagatgatc tgctgatcca gataattatt cagcgcgtcg ctaacaaatg gataagctag
    76801 tatccctatt cctgagagaa gcaagaaaag catcagcaga tctagaagtt tccttttctt
    76861 tggtttcatt tgtgttctcc ttgtgatgac tgtttgataa taaaagaaaa aggagcattt
    76921 gcgtaatccg ctgctccttt ttccaattct tgcaaaaaga ctaaatctga ctgtgcttgc
    76981 gtctagcaaa gtacagtcca gcaatcagta gaaggactac tcctgcaccg atatacacat
    77041 agattccctt accgcctgtt gaaggaagtg tacctttgtg tttatttggt attttttcag
    77101 gagaaatcaa ctgtcctgct gttacataag attgttcatc gatagtaaat gctacacggt
    77161 ttgttaatgg aacatatttt tctggcgctt tcgtttcttc cagatagtac gtgccatatt
    77221 ttagacctgt cacatcgatt aaaccgttac ttgtggttgt aaaaaccgtt gctgattctt
    77281 tcgccgatac ccagctgacg gcttttgtgg atgggtcgat cgataaatat ttcgctgtgt
    77341 cactatcttg atcacgaacg acgaattctg ctccagcaag tgtttggtct gatgtaacgt
    77401 caccatctac tttaacaaat cgtttgcccc cagtaacgac atcgactgac ggtggtgttt
    77461 gatcatttgt atgcccgtta tcgacatttg cttggttaga aaatcctttg gttggatctg
    77521 ctttttcgtt caaatgcata tagtaaacga atttcaatgt accgccagga gttaatgaag
    77581 gaatataatt cggatcaact gaaaccgtga atccgtctgt ttgctcagtg acagaataat
    77641 ttactgggtc gatttcttta tttccatcat ataaggcata agcatacgtt cctgaagaat
    77701 cattatcaaa tgttaaagca gcgtcatgag tatcgataag tttgaatgtt gtgtacttgt
    77761 tttgcgttcc ttctttatca gcgataccta atgggatatt gacagaaatc tcatattgaa
    77821 ttttttcacc gattgcgaca tcttttccat tcaattgagg tgttgtttta tcaactttag
    77881 acgtatcatt tttgatggtc ttttctactg gtgtttggct atttgccagg atctcaaaag
    77941 gcgtgattgt ttgcttttca atcatttccg cattatcagg agcttttact tcttctaaat
    78001 tatattttcc aacttctaaa tgattaacga tcaactggcc tttttcaata gatgcctcgg
    78061 caaagtcatt gttgccgatg tcataagaat gaccagtaat gaaatgtttg gctttggttt
    78121 gatcagttgt ccaagtgtac aatccatctg tgacactttg gatgtatttt ttgacgcttg
    78181 gtgttccttc ttctttagaa ataataaatt ctgctccatt tagtgcttcg ttttcggcag
    78241 taccgatttt tgtaactttc aacgttccat cattaccgac tgtattttta gggtagagat
    78301 ggatagtatc tagttcttct gtcccgtatt tataagagcc atctgcttgt ttgatcatct
    78361 catatacagg gaaagctaaa accatgtttg cggcagctga cactccgtct tttggttctt
    78421 ctttgatcgt gtagactgca tctttcccat tttgtttttt aggtaaagat aaagtgacat
    78481 ttccatcagc atctgtcgtt cctgaagcaa ctggtgtacc aggagtcaaa gactggactg
    78541 cttgttttgc tgcatccacg gacgctcctt tatctcgttg cgcataaaat tcttgagtga
    78601 cgttataaac tgaaaatgaa atatcggcta atccttggta ttgatcgaat tcgctcattt
    78661 ctttcccgct gttttggatt aaaggatcgg gtaaatcagt cattttcttt ttatgaagga
    78721 tgacttgagc tgctgtctcc tctgcaaaca ctttttttgc gccgaagctg tttgtgagta
    78781 atggtaaaat aaggaaaagg actcctaaca taacgtttat ttttttatga tttttcattt
    78841 tttcactcct gttctttttt tgataaacaa ccagattgca aagcttgcga ataccatacc
    78901 aacaacgcct aaaagtgtat ttttcgtttc gtttgttttt ggaagaaatg gacggctatt
    78961 ttctttttta ttgactactt tcaatatact gtccgcctct ttatcctcag aaagaaaagt
    79021 tgaaatggta aacggaattt ctgtttcact taaaatataa ccagaaggtg cttcgatctc
    79081 ttttaatcga taacttcctg ttttcaaccc ggaaattgaa aaagcgccat ttttatcgga
    79141 aatcaggtga agcgcatctg attcgttctt tgtccacttg tatccgttgg ctgtttgctg
    79201 gaggtaattt cctgctttgt ttttaataag gaatactgcg ccagctaatc gtttatctgg
    79261 tttatttgtc tcgattttga caaattgctt actccctgta tatacagaga ctttctttgt
    79321 actgacacca aaaccaaaat ccagtgttcc gttgttgttg atttccttgt tcgcctgtgc
    79381 tgtactgctt agctgcatct gataagaaat ggtcagtttt tttccagcat atttttccaa
    79441 cgaagggatc gaaaataaaa catcaaatcc gtgaggtttc ttgtgtatga caaagccttc
    79501 tgtcagcttt tctccattcg atgaaatcgt taaactatta ggtaaaaacg ttaatgcttc
    79561 atccgcacta tctgacaatt cgaacttttg atagtcaagg atatttacag gaattgtcgt
    79621 atgcaaggaa taagtgattt tttcaccaat cgtaaaatca tttctaggct cttctaatac
    79681 cttctcaaaa ggtggatcag ggtagtcgtt ttcttcattt ttaggataca aatggatagt
    79741 tgaaagtttt tgattgtttt gtccatgtac aggaagaaca actaccatat tctctgcctt
    79801 ttctttgacg acttctggta ctttggattc aatgaaaaga tacgctttat ctcttttttc
    79861 ttgatcttta gcggccagag aaaaagaagc gataccatct tcgttgttaa gagttgtagt
    79921 tgttgcttct gcggtaaaca taccggaaga cgcaccgttt tttgcgatct ctgcttgtgc
    79981 ttcttctacc gttttgccct tttcccgtag atggtaaaaa gaatctgtga catcataaac
    80041 ttggaatgtg acaccattta atcctcgata cgtttgtaat aaagcttttt cttgtccgtc
    80101 atttggatga tttttcggca gttgcccgtt tgggaaaagc aatttgtgta aagtaatctg
    80161 aaccatttct gtttctgttt ctgttgctac ctgagtaaaa gctggtttaa atagtaacaa
    80221 gaagagacac atactaagcc aaccaagttt tttcatattt agctgccccc tctttctttt
    80281 ttcaaaaaaa gataccaaat agaaaacgca caaccaatca tccctactag atagattcct
    80341 aaacggccaa ttcctcccgt ttcaggtaat ggtacttttg cctgattcgt gatgtctaaa
    80401 gaaatctggt tgtttttggc tcctggtgac agaacagatt catgatcttg tccatccact
    80461 tgaattgacc catcttcgtg tataactata gtaactggct cttttagacc ttggtatcct
    80521 tctggtgtaa aagtttcggt cagcgtataa gttccaggtt ttaaattttc gaatagaaag
    80581 gtatctgttt cttgtccatc ttttggcgat tctaagtcca tttctggtcc ctgcagtctg
    80641 aattttgctc cttttaatgt ctgtccgttg tcttcttttt tgtgtaccgt tagatcaaac
    80701 gcttttagtc gattttgatg agtgagcgtc catacattat ttgtcatctc ggtatttttt
    80761 cccgtgtaaa tgatttttcc atatttatcg atttggaatt cataatttcc cggcgaagta
    80821 tcatatccgg caggaccagc tgtttcaacg actcgatatt taccaggtgt gagtgaatca
    80881 aaactggcaa gacctttttc attcgttgtt tggctgtcaa ttggctgata agtaccattt
    80941 gcttcttttt tctgtaggga aaatgctgct cctttaagat ttatctcttt gtccgtccct
    81001 tgcatcgcat acttacgtac tgctacagga acttcaacaa aaggattttc aatagtcaac
    81061 tggatcgtat catcggaagt agtgactgtt tttccatcaa tggttaccgt accatcagaa
    81121 gcgatcttga tttcccaagt agtctttttg cttaatccat gcccttctgg agcttttgtt
    81181 tctgtcagcg tataggtcat ttctttttgc aatttgacat tttctggaag agaataggtt
    81241 ccgtcgccat gatctgttag taaagtatca atagaatctc ctgttaattt gaaaacagcg
    81301 ccaataagat ccttttcacc tgtagaggaa tttttcgtta ttttcaagtt taacggtgtg
    81361 aattgtttag tatttttcca tgtcattgca tctatttgtt gagaatcgta tcctggtaca
    81421 ggtaattctt tgattgtttg gtaactgaat gcttgacctt gattattgta ttgaggtagt
    81481 gataatatct cttgataact ttctccgcta tttgcagata atttgtcaat gtctgcacgt
    81541 tcccacgtat ttgttgtatc tttagctggt ttaatgattc gaatatatcc gtttttccaa
    81601 gctgcagcat ttgtcgtatg ttcccgttga atctcaaaag taacttgatc tggacgatca
    81661 gctagattgt tgtcaaattc ttcccataac tttttgatgt gaagactgac tccgggagct
    81721 ttagcagatg gtataccgaa ttcagctaat tcattggtat caatgtttgg ctggaaagtt
    81781 gtcctgccgt tcatttgata ccagaaattt ggatggaagt cctcattttc tgtttggatt
    81841 ctcacttggt aatggatttg gatttcttgg tcttttccta aatagatctg attgctcttg
    81901 atggtatttc cttctatgga aatagatgga gtgaccgttg taggacttgt ccccacactc
    81961 ttgactgaaa gtgtaccagg ctgataaatg aatggttctg cgattggatc atttatttgt
    82021 ccattgctta cagttgctga gatctgtaca gcttttttgg ctaggtattc agagatatct
    82081 gttgcatgat cagctgattc atagtaaaga tcgccttttt catctgatga aaccatttgt
    82141 cgcatacgag actctacttc tgcttttgag agaccagctg ccggatcgct ttgaagttgg
    82201 atgccaagac catgtatttc gattcctcgt tctttgagtg ccatcgcttc tccgatggtt
    82261 gcgataaacg tactgtcgat tcttctggat agattgtttt ggtcaggtgc atcatagatt
    82321 cttgagatta gagaagtatt tcccggccga tcttgcgtat tagaaaactg agttccgtaa
    82381 taattgctgc ttgattgtgc gtgtacccgc tgtactttat aggaaaatgt tggtacacca
    82441 tccgtcagca aaacgatcac ttttttatgt ccatttggaa cggatagcat gcttcctgca
    82501 tctcttagtg ctttttgtgt aaaagtacca ccatttgtcc gtgaaggtgt aatggatttt
    82561 acttgatttt tcactgaatc aaatgaaccc atctgtactg caccgttact gtagctatat
    82621 ccttcgcttg agtagccgac atatcccata ttgattttgt ctgtgatacc gctatctgct
    82681 aaagtatcga caaaacgatc gacaccaatc tttacttcac cgatccgatt attgtcgttc
    82741 atacttcctg accagtctac gaccaatacg agatcaagag gcgtgatatc tttttgtaca
    82801 tttccacgag cattcaaata aacatcaaac aatccgggtg tacttgtttc ctttgcatac
    82861 tttcgtatcg catagtctgc ttgattaccg gttcctccat attcgatata cgaatgggtc
    82921 cgatcattag gatctccatt ccaagaattt ataccatccc attgatttgt tccgttttta
    82981 ttgccttgat gatcaagaac atttgtattt cctgtaggtt gccaactggc tttaggataa
    83041 gtgccctgat catctgttgt atattctgta ggaatcgttt gattagatgg cacactcaca
    83101 gctggcaagg ataatgtagg caatgtaaat gggctgacag aattttcgtt ttcttttgat
    83161 gattcttctt ctatttcgtc tggctttggt actgacacat ctgtatcttt cttattttct
    83221 gtctcatcaa taatgtcata ttctttatta tcgacgatca gcttgtttgc ctggctgtgg
    83281 taaagtgctg gatcgattgg aaaactcaga tcgatagttt gtttagtgtt tgatgagatt
    83341 tccaacgtaa ttttcccgct atttacctga taagcatagc catctccttc ttttctttcc
    83401 acatcactta agtaattttc gactagacca atttcttttt ctatcttttc agcactggtg
    83461 ttattcgcat ttagcttgat gttcagtgct ttttttccag actgatccga aatgacttca
    83521 gctgaaattg tttctaaaac tgttggatca tctgtagtgt ctgctattgc agataatggc
    83581 acaaagtttg ataaactcaa tattatcagc atgaaaataa ctttcagttt cttccctgtg
    83641 gtcgtcattt ttcccctcct ttttcttttt ttctgttttg acgtgaatag tgaaaattat
    83701 taaaataaac aggcgttaca taattttatt tattttaata tgataattat tatacgaagg
    83761 gcgctaaagg gaatcacacc aattttcata ccaattggtt tcatttatga agttgattcc
    83821 ttcgattaat gagcgtttca ttgaaagaaa agggttgagg gagaaaaaca tatgatcagg
    83881 ttgttggaac gaaactatag aaagatggaa aaaatcattc gaattctgtc catttctgac
    83941 aagtggatga ctaaaaaaga acttgccaaa cgaattggta gttcagaatc tacatttgta
    84001 aggtataatc gaagagatca aaatccgctg gggaacggat gtaacgattc aatcttcaca
    84061 aaaattgggg tatcgtcttg aacatttgaa tgtaccagct tatttaaatg ttctgatgga
    84121 aatgtcgcaa agttctacaa acagtcgttt attaaatgag attattgtca atccgggtaa
    84181 aacgattgag tattattgtg aaaaaatttc catcagccgg tcttctttta cacgtaagtt
    84241 gaaacaatgc aatcaaattt tagaaagcta tttattaaaa gtgatcgttg accaaggttt
    84301 tcagttaact agccttaaaa gtgagctcca gttgcgtatc tttgttacct ttttcttttt
    84361 aagttactac ggaagacgca cgttgccatt tccaatcgaa aaaaagaaga tcaaagaaat
    84421 tatggtcaag aataattgtc agatgaattt gtttcaggaa gaaagcccat atgagcaatc
    84481 tttctttatt atgtattttg ttgtgcatct catgagagaa tcccaaggaa ctccatttga
    84541 atggaaagct ggagactctt atgtacagtt gataaatatc gataaaaaag acttcttaat
    84601 cttgaaaaat ctcttaggaa aattgaagta cagcagctat ataaaagtag tgaactattt
    84661 tgtcaatacg attttttcag aattttcgga gaaagaaaaa aatgaaatca gtgagcagat
    84721 acgaaaaaat atgtcctact gttcgttttc atccgctgat tgcaaagaaa aaaacgaaga
    84781 atatgttgtt caattattaa cgcaaattta ttttttctcc cgtattttcc catacgatac
    84841 gactcatttg acgatccgtg caacttactt tgcacagcag atgcaacacc gccagatacg
    84901 tctatatgct ggatttcgtg cagaacttca attttattcc actctactga atcagaatct
    84961 gatttattat ttatctagct atatcttttg gatgcttatc ggtaatcctg aaattcacca
    85021 ttatacttct gataaaaaaa tactgattat cagcgactta agtcttcgac atagtcaata
    85081 tattgaagaa tatatcagtg atattcttgc tgtgcataaa attcactctg agacaactgc
    85141 tattactgaa gatcagctgt cgaaatacaa tcttctcgag tatgatctga tcgttacgaa
    85201 tcaacccatt ttgaatgccc atgttcctca tatattgatt gatgatagtg tgtcattcgc
    85261 aaatgaagaa gaactcatcc gcttattcga gttatgaata atcaaaaaac agctatgtat
    85321 aaaccaccct gataaaaatt tcaggacaaa tacacatagc tgtttctttt tattgtattc
    85381 cttcagcaat ccaacgagat ttatagcgaa agtcttttaa caactcttct tttgtccaat
    85441 tatttgcaat gagatccgtc aaagtgttca ttacgagggt catggaaaag tataggaaac
    85501 taactgcttc ttccgacgat tgaatggaga aatgattgat tcttaataat tccagccatt
    85561 tttcgttcat tggagaatca gccgatagtt ctctacgttt ggttgtctgc tgatcatttc
    85621 gctgggttaa caagtataac ctttgccaat agatactttc gtgatctaag tcgcagcacc
    85681 actctaaata tttttcgatc cccaaaaaga aatgttgttt gttttcgcta atgaatttta
    85741 agatatcttg atggactatg tgagaactgc ttttgatcgt atacaaataa gcatcttcca
    85801 aatcttgaaa atatttataa aaagcaccgc gcgacatccc catcttgtca acgatttctg
    85861 agactttgac ttggctgatg tgctgtgagc aaaatatctc cagtaatagg tcatcgattc
    85921 tctgtttctt tgcgttcgat aaattgaaaa aagtttcttt tggcatccac atctctcctt
    85981 tatctctgat tatacgtgga tagcccttca ttgtcatgaa ggattcattc cttctttttc
    86041 tcttcttctg tcaagtaccc atcttccatt cgataaacgc gatcactcca ttgaatcata
    86101 cggacatcat gagtaaccat aatagtcgct ttttgtttct catgagcttc tttaactagt
    86161 aatttgacga cttcatatgc atgatctgta tccaaactag ctgttggttc gtctgctaag
    86221 atcaagcttg gctcattata taaagcgcga gcaattgcca ctctctgtct ttctccacca
    86281 gaaaggtctt taggataact atttttaagt gactggatat ctaaagattg cagcaaggaa
    86341 tcgatttttg ttgaatcttc tttttttgaa gtaacttggt caactagttc aaattgttcc
    86401 tttaccgtta aaaaaggaat caaattagag ctttggagaa taaatcctat ttctttaaag
    86461 cgtaaatctg ctcgtttttt ttctggaagc tcagttagtg agtgaccgtt gatcactatt
    86521 tctccggaag tcggtgtttg caatcctcct gaaatggtaa ggaaagtact tttacctgaa
    86581 ccagaaggac caatgatgct gacgaattct ccttccttta cataaaaatc aattgctttc
    86641 aaagctgaga cctttgtatg accagaacca aatgttttgg taactttttt catcgttaat
    86701 atttttttca tttttattaa cctcctattg ctgtaattgg gtctactttg gttatcgtac
    86761 gtatcgaaaa caatccgcct agcattgcga caatgatcaa aatcccacta tatagcaacc
    86821 attgtgacca aaaaacagca aaaggcatcg cgcttggtaa aatcagacta gtcaaataag
    86881 caaacaaaag agcaagcaga acgcctacca ccccaacaat aaaggactgt gctactaaag
    86941 atttagcgat gaagaaattt ttgatccctt gtgctttcat tactccaaaa atagcagtct
    87001 tctgaagtgt catcacgtac atgaaaatac cgaccacggc agcaaccact aagaacaaaa
    87061 agtatatcat cgcatttaag gtcatatttt gggcagaata gccaggaata ctttcaatga
    87121 atgtcccaat agttaataac tgtagaccct tcgatgcttt ttctttcgaa attttagctg
    87181 aatcctttat tacgatccca ttgatcggct gttcttcttc agaagcaaac ggctgttgtc
    87241 catacttcaa agcagtccac gtatctaggg acgcatagat gacgggagaa actgtgtaat
    87301 aagtttcagg aaagataccg acaatcgtca aaggatcgtc gtaactgcca attttgatcg
    87361 tatctccaat tttatagcct gaatcagcca gattttgaga gatgatgatt tcattctttg
    87421 ttttaaattc atgccctttc gtgagttttg gtaataaaaa tgcttctttc gttgtgccga
    87481 aaactgtaac attttctttg ttttttcctt tgattgctcc gctgtacaat ccgattggtg
    87541 ctttctctcc tccttcaatg tatttcagat ctcctcttgt taattgtgaa gctgcaaata
    87601 cttgatttgc atcctccgac aaaacaatct cttgtgcgtc ccaatcatcg attgcttttt
    87661 taaactcttc tgaaagtcca ttcgctagtc ctgacaacat gaatacgaca tacgcaatca
    87721 agaacataat accgacgatc aagccatatc gtaatttaga atagcgaatt tctttgatag
    87781 ctagaaacat ttgtttttcc tccctatgat agattgatag tgacaaaatg tcacttgttg
    87841 aatagtgtaa ctctaaagtg acaatttgtc acttgtgttg tttttttctt atcaataaat
    87901 tgtctaagac atctttcgat aaaaccttaa catgagtcat aaaaaattta tttaagcctt
    87961 atttatgctt tccatgataa actaaagtga ccaaatcaat gaggtgggaa aatgattaaa
    88021 ctattagtag tagaagacga taaagtatta tccaataata taaaagaaat actcgctgca
    88081 atcggcgaga taacacaagt ttatgatggt agtgaaggac tgttcgagtt ggaaagtgga
    88141 gtttatgatc ttgcaatctt ggatttgatg atgccggaaa tgaatggata tgaagtgtta
    88201 gcaaaaatac ggaaagaaaa aatacagact ccagtattga ttttgactgc aaaagatagt
    88261 ttggaagata agattgaagg atttgaacga ggtgcagatg attatctaac aaaacctttc
    88321 tatcgagaag aactgatcat gcgcgtgaaa gcattattga aacgctcgct aggtctcttt
    88381 gatgaaaatg ttctgaagta taaggatatc agttgtgatt taaaaagcaa tgaagtcttg
    88441 tataaagaac aagttttgcc catacaagga aaagagtttg aattgctcgt ttatttttta
    88501 caaaataagg gaatcatttt gacaaaagag cagatatttg accggatctg gggatttgat
    88561 tctgatacga cgattacagt tattgaagtt tatatgagca acttacgaaa acatctgcga
    88621 agtactggat tggataaaga aatcaaaacc ttacgtaatg tcggttatat actgcaaagg
    88681 gtgtgatgca atgaatggag atattacacg aaagcaacgt agtcgctttt ttgcgacaaa
    88741 tgtagcagca tttgctttta tcttttttct tttgggattc attactttac agatattaaa
    88801 ccaatctgca tacagagaaa cagatctgtc attagagaaa ataaattttg attctcgaac
    88861 agtacaatta gagatacaaa gatatcagca aggcgatccc tttttaaacc cgactcaaac
    88921 ggaacaaaac agaacaaaca tggaacagcc attaatggaa ccatcaaatg accgttttaa
    88981 cactcaagtg atcttgtggt ctaaaaatgg tgagatattg aataaagcag ctattggtgg
    89041 gcgtttcaac caaatcaaag aattaaaaat ggatacgaaa aatctgaata ccatccaaaa
    89101 tattgaatta aatgaagaca gtggctcatc tgccctctct ttccgttcga ttacgaaaaa
    89161 agcggagacg aatcaagatg gcgttgccta catccaaatt ttagaaaata caaatcaaat
    89221 caagaattca ttagcgactt ttcgcacgat tatgattttg tgtatgattg ttttttggat
    89281 tctctctatt ggtatcagtt attacttgtc tagtctaagc atgcgcccta ttattctttc
    89341 ttggagaaga caaaaagaat ttgttgagaa tgcttctcat gaattgcgca caccgttaac
    89401 gattattcaa aatagtttgg aacatctttt taccaagcct aatcatacta ttattgaaga
    89461 atccgaaagc atcgctcaag cattgtcaga gacgaggcgc ctcactggat tgacttcgga
    89521 tttgctgaca atcgctcgga atgattctga tcagcagctg ctttcaaagc aaatgatcaa
    89581 tacacaagaa tatatcgaac aacttgttaa accatttcaa gagatggcca tcatagatgg
    89641 aaaagagttt attctccata acgatgcaac attagaagta ccaattgatg aaaaaaaaat
    89701 ccatcaagtt ttggttattt tgctggataa tgcattaaaa tatacgaatc cagaagataa
    89761 gatcattttg gattcatctg ttaaccataa agaatggctg attcacgtaa agaatactgg
    89821 cccttctatc agtgaagaag atcaagcaag gatttttgat cgattttatc gggaagatca
    89881 atctcgggcg aaagagactg gcggatacgg gcttggcttg gcaattgcaa aacaggtaat
    89941 cgaacagcat catggacaga tttctgtatc caattatctt ccacaaggag tcgattttaa
    90001 agtccaattg ccgttgaagc ctaaaaaata atgcttatcc ctaaaaaagg gctgtgacaa
    90061 aaatcttgtc acagcccttt tttgttgcga ataaacggtg ttccagaagt agcttcttcg
    90121 gaaataagcc gaaatttctt taagctgacc acttctgtca caacctcttt agcttacgct
    90181 tacgattttt tattgcggtc ttcaatgtgt acatcaccgc ttgtgtcaat atccaattct
    90241 tctcggctaa catcttctgt cactttttca acatcttcat gttcttcttt atgaatccca
    90301 acttcttcac gaataactgt atgtttgctt acatctactt gctcttcttt gattgggata
    90361 gtaatcgtgt catcttccaa tttttcgtct gttccctgtg aagattgatc tgttactggt
    90421 ttgcgttcga tgacgatttc ttcacgtttg accggtactt ctaccgtttc agtatcgttg
    90481 accacatgtt tgtggatgtc gacttctcca gttgtcacat catgtgtatt tacatctaat
    90541 ttttcttctt ttagttgaat tgtatcatca tctagatttg gtttgcgatc gatgtcttca
    90601 gtcttgcttg tacccattgt atcagtctcg ccaggtacgt ccatcggatc agttcctggt
    90661 gtcatattca atggatccgt tgtattttga aagcctgtcg tgccacctac gtccattgga
    90721 tctgttccag tgccagtttc taatccagtc cccattgtgc ttgctgggct aacagtatct
    90781 tgtgtatcca ttgtatcttc tgttgtttct ggctgacgat agccttttac tgtgatgaca
    90841 aattttccat cagaaatatc tcctctatat tgatataaag gatcattttc tggtgtagcc
    90901 gtctcagaat cataggtatc aaaagaaaaa gtatctttta ttttttccca taaagaacgg
    90961 tcttcttcac catccatccg attttcatct gtttcaacat ctataccaga caatccgtca
    91021 aatcctagtc tagatgctgc ttcatcagta gtataaataa cgatatcatc tcgttcatac
    91081 ccttcgttac gcaaccgttc aattactgat aatgcttctt ccctcgtact atagcttccg
    91141 atgaccgtta aatttttctc ttccatgtaa attcctccta gcaaatagat ttatgattgg
    91201 tatattgtta cttataaatt tattctatag gagacgattg ttttctacaa atatttagat
    91261 tggaatttga ttaaaacaat ttaattgaaa tttgaaaaca tttatgttaa tgaaagtcat
    91321 attctaataa aatgtcattt gtttctatat gaatttttat gaaaaatttc atataatttc
    91381 cactcgttgt gatggtttaa tttatccaat ccatcaataa gcaaacaact tatataaaaa
    91441 aggattaatt ctcaatataa ttgctcctac catagaataa atcttcatgt aaagtaatga
    91501 agtaccaact atttctaata cttctttaag aattatccca acaatatcgt tagacaaacc
    91561 attattgaat aaatggagag ccaatcgatt ctgaaaaaat gttttctaat ttttcggaaa
    91621 taaaagaaag agcctcctgc cattagaacg aaccaaatcc atttcattgc tcatgaagta
    91681 accacatagc taaaaagagg ataaatcaat taaaagatca aaagaatgac tgcactaata
    91741 aaataactaa aaatgtatct tcttacttca tatcttttag ctagtactta gttaaaaatt
    91801 tgcttcctaa gatcaagaca aactgtctat cttcatttga tgaaatgcgg taaaatatag
    91861 aaaatgaaca ctattggagg gaatttgtaa tggacagcaa aactagaaaa caactgcaag
    91921 aaaagttaaa gcaacgtaca cacttgctcc cttccgtctt tcaacagttt ttagaagaaa
    91981 atcgttcttc cctttcatta ggcagtcgct atgaatacgc aaaagatttt catctgttta
    92041 ctgattattt gagaaaagta ttttctgaag aagtggatga tcagctgatt atccatttag
    92101 aaaaacaaga ttatcagaat ttcttagcta aaatctatcg acatactcgt tcgttccaaa
    92161 ctacagcgaa ccaagaaacg gagcaattgt ttgaaaatag ctattacggg atttcaagga
    92221 agcaatattc attaaatcat tttttacgat ttttgtatca aaaaggactg attgaagaag
    92281 agatttctct tttgggtaca agtttaccgg aaacaaccaa agcagctccg cgatatatcg
    92341 atgcagaact tttcaaagat tttgagcatt tgtttatccc gattgaaggc tttcaaacaa
    92401 gcagagaagc tagctttgaa gaaaagaata gaccgaggaa ccttgcaatt actgccattc
    92461 ttctgtattg cggattaaag atccatgaag tagtagaact taaacgtaaa gatgtatctt
    92521 tgaccaagca gattcttaat ctgaatagaa aagaaaacag actgaataaa gtaccaatac
    92581 caaaagaagc gatgccattt ctggagaact attttaagtt aacagcacaa aatacggacg
    92641 aaaattcttt tgtttttcgt tcctcacatg atcagcaaat ttctcctcgg actattcgcc
    92701 aaattttgag caaaattaca gtatataaaa acgtatcgcc agaactatgc agaaaaacat
    92761 atcgttatta tgcagaacta tatttagatg atgctgacgc ggtaaattat ttatgtggta
    92821 atcgatacct ctcatcccat tcttttcaag atatctggga aaagatggtt gatttttctt
    92881 atcacgaatt agcggcattc gttcgggttt cttccatata aaacaaatgt atgatctttt
    92941 tttcacaata aactatgtta ttatataaag gattatgtta cgattatctt gaatttgtat
    93001 attacttaac aaaagataat ggagtgtgaa tgatggagac cataacgtat tcccctttga
    93061 acttatttac gaattttcaa gaagctgcag ctaacttttc cgagaccccg attatctttg
    93121 atgagccact ttcagctttc ccagaattag gacttgaaac aacttacaaa aaatgctgcg
    93181 aaagtgtgtt gaaacgggct tatcaattgg ctcatcttgg agtgaaatcc ggagacaaag
    93241 ttattattta taagagttcc gcttttgaca cataccttct agctgtttct gtgtcttacc
    93301 ttggtgcagt gcctgtcatg acttcttatc atctaccaac aacaacaatg gaagtattta
    93361 tcgatcgttt agaagaccct ttcattttat ttgatgatga gacaaaaaag cgagtgagag
    93421 aaatttcaaa tggaacaaaa tcaaaacaga ttcc
//
LOCUS       DAFBVQ010000005        92224 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.005, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000005 DAFBVQ010000000
VERSION     DAFBVQ010000005.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 92224)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 92224)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..92224
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.005"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(552..2165)
                     /locus_tag="LLC22_000393"
     CDS             complement(552..2165)
                     /locus_tag="LLC22_000393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5433699.1"
                     /translation="MKVVVIGGVAGGPSFATRFRRLNEAHEIIIYERGENISYASCAL
                     PYYLGGVITDRDSLIERTPEILKTKNNIDVFTKHEVTAIDPSTKRLTVKDLSTNEEIK
                     TDYDKLIISSGARPDYPDIPGVFEAENGFVLRSVTDADRIKSFLEEKNPQHVVILGAG
                     VMGLELAENFKHRGLDVTLIDQLPQVAFPYDPEIANLVYDKLLKEGLAVHLETRVTEI
                     RDKGREIVLSDGSVLSADMLIFAVGVSPKNEVVKATGIQLSDTGQIIVDDQLQTNLPD
                     IYAIGDIIETTSVVTGQPIQSMLSSAANRQGHMLADILNGTPMRYRGYIGAGVAKIFD
                     HTASYAGMTEHELKASGITNYKTVFITPFDHAYFYPEATRLNLKLIFDADSGRILGGQ
                     AFGEKGVDKRMGELSVAITGNLTVFDLPDLELPYSPPYSTTRDPLNIAGYVAINQMTN
                     IVETIKASDIPENDLKEAFFLDIREPNKAPSGSISATKNIPMNELRDRINEIPKDKKV
                     YITFRRGLNTYTSARILAGLGIKAILIEE"
     gene            complement(2306..3214)
                     /locus_tag="LLC22_000394"
     CDS             complement(2306..3214)
                     /locus_tag="LLC22_000394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5433700.1"
                     /translation="MVLLLTNNQSSNLVKKTLTYSIDTHLHLSAAPYFRLLINESANL
                     YAEFAHKSIELDNPSLLFIDKQQEVQIFSTQKETQTFIIIQFYFDEQLLAHITGQSFS
                     IDQEITSIITFLKNEQFKIDYLKHSKPAISYDQEINSFFILCQQMSIHLLSLLVTYCL
                     QKIQLSSLPRHYQQELALLTIPSNEKVIPKKKHILYSDELVDPIIRYLEEHLSENFLL
                     EQLAQIFFISPASLKKHFRKVNGKSVISYFKELKMEKAKRLVLENELTYTEIADILGF
                     HSIHHFSSAFKKYTGLSPSKYYLSLK"
     gene            3397..4521
                     /locus_tag="LLC22_000395"
     CDS             3397..4521
                     /locus_tag="LLC22_000395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5433701.1"
                     /translation="MKKRYKLVIALLNITLLFSLSACGKTNEEVTANIADPMIKKATT
                     LEVYVANGKLTNYVENAAKIYNRKTGANIDLKIVNVASGTATVQMITPKLVTHEDMPD
                     IISMADTSAAGVLEKFQDAFYSADEYGFYDKYGDQFYDQKLNILRQQTSNETIIPWAS
                     DFTPALCYYQPKKFAEIGVDFEEISSWEEYIQVAKALKEKTGSFGIALPESGDQELFI
                     NMLAQQNQSLLDEEGNIRLNTKEAKHAAKLIKEMIDSDIVHFYGAQDAEKAFQESAMF
                     VAGGWYATNMSLNFPDASDKWRMAPLIPFSKENPGKGAVSGGSSFYVPKDAKNPQVAQ
                     QFLTFMLTDEECLANALELGVATSNSLAYQTEAAEKKFDY"
     gene            4748..5665
                     /locus_tag="LLC22_000396"
     CDS             4748..5665
                     /locus_tag="LLC22_000396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5433702.1"
                     /translation="MMQSSLPSKTIKNSKKKATDTSHKKSAYGLVTPFVIFFIVTILI
                     PIIISFAFSFMKIGYSFEFVGFDNYLAIFRDPLFIKSYTNVLIIMAGSIPITMLLAIY
                     FAVLLNSAQLKGKGFFRTVYYIPTITSTVAVASVFMTFFNPTGLFNGFLNALGINGVQ
                     WLTNPFWIRISMIITMIWLSVGYNTILFLAGLQGISKEIYESAEIDGASKFRQFFLLT
                     IPMLKPIILMATVLATINGLGNFNIPNIFFGTSNGPENSALVVGVNLYKTSFEMVDFG
                     KASAIAWTMVFVSVILSAIQFKFGGDKND"
     gene            5658..6491
                     /locus_tag="LLC22_000397"
     CDS             5658..6491
                     /locus_tag="LLC22_000397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287754.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5433703.1"
                     /translation="MTKQKIQSRIFTYVIIVFGALIFLMPYLYMIVASTQSNQEILSG
                     GINFKFGDMLLKNWQAIMARYNYPLIIWNSIVIAVISTVLATASSTMAGYALAKYRFM
                     GNKLLFNTVMLSRMVPFFTTLIPLFYIMSRLGLSNTYAGVIIPSIASTTSVFMMRQYS
                     SQFPTALMEAARIDGANEWVIFTKIAVPILSPTIITSGLLIFMGSWNQYLFPLVMLSD
                     KDKYTVPLIIKNMTVSSTGEPINYGAIMLILATSVIPMVLIYVWAQSKFKENDIGAAN
                     K"
     gene            6574..7692
                     /locus_tag="LLC22_000398"
     CDS             6574..7692
                     /locus_tag="LLC22_000398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBK5433704.1"
                     /translation="MNEQTKEWSRKILNVASEKIDAELDRMGNKIPYISYNGKYTDVI
                     KDRGIDWWTNGFWSGILWQLFHKTKREKFKEAAIQQEQLLESALYHFSDVHHDVGFLF
                     LPSAIAHYQQSQNKHSRQLGLHAATVLAGRYNISGNYLVAWNDHKPGWMIIDSMMNLP
                     LLYWASRETGDPRFSKIARQHADTTAKYLVRKDGSTGHIAEFDAESGKYIRLLGGQGY
                     NENSCWSRGNAWALYGFALSYRYTKNPYYLAIAEKIAVNFIQKIEKTGYIPLIDFAVK
                     DSNIDTSAGVCAACGLLELAGYVSSVRSKMYHEAAINILQKTEKHYANWNMDEDGIIG
                     GGAEAYHRELTYNVPLIYSDYFFIEGLLRLEQSELAIW"
     gene            7686..9584
                     /locus_tag="LLC22_000399"
     CDS             7686..9584
                     /locus_tag="LLC22_000399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2264 domain-containing protein"
                     /protein_id="HBK5433705.1"
                     /translation="MVVKRGENTMKHPVPLLRTRQDYFDLFKKINQPLQPFYRASGAQ
                     IDYIHQGVGYGNKIAGMEGFSRVLWGAGPAIDQLDERWLKLILSGIKAGTDPSHPDYW
                     GEIHERDQRMVEMPAMLLALYHHEQLLWKKLDTGEKSQIIHWFSQIFEYECADGNWQF
                     FKIIVGTIIQKFGYPVKESALKEAFDNIENCYLQNGWYRDSSRGRQDYYNPFAFHYYG
                     LIYSVLEPEKPISQIYKNRAIDFSRDYIHFFAEDGANVPFGRSMIYRFAVSSFWSAML
                     WADLLPFKLGEIKGLVNRNIRWWMQKEIFDEKGILNIGYTYPQLTLTEPYNSTLSPLW
                     LNKIFLLLALPEDHEYWTAKEMPMPIREGTKLLSEANLLIQHDNGHTFFLNAGQLGPN
                     FHTLTNEKYLKFAYSSQFGFSIPRANQLKAEMAMDSMLGIQRADTYITTSFKNESIKT
                     YGQFIVRNNVRDIVCKKEVLASTWEPTLQAKIRTWLIPFEGWQIRVHKVELDTEYVLY
                     ETGFAIECSPEKEGIIIEEDKENYRVSEAGFSGIICLSDDTIKRKSTAIMGLPNTNLM
                     TWENTFIPGLEGTFGKGTHWLGTGVVAHQDRDYSLEVWNNRPKIDFDGTTGLTIQNKN
                     NKKRLKLC"
     gene            9578..10801
                     /locus_tag="LLC22_000400"
     CDS             9578..10801
                     /locus_tag="LLC22_000400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBK5433706.1"
                     /translation="MLKAGGEMLDKVMFEEIIHPEKWINECYKELMEKEWNNEIERCR
                     RHTERLIKRISNSQYQFPSECPIKGRYPLRDNIGWTEGFWTGINWLLFEKTGDPLFQQ
                     TAEKADIDFIHRIDCQIITNHHDLGFLYSLSTVADYKITGNRKMKEASIDAAETLLQR
                     FWEKAGVIQAWGDPSDPSQQGRMIMDCCMNLPLLYWASEETGNQKYKKAAQAHIQNAA
                     DYLVREDGSTYHTFYMDVKDGKPRYGSTHQGYSDNSCWARGQAWGIYGFALSYRYLKE
                     QKYFDLSKILANYFMNRLPEDTICYWDLIFDDSSREEKDTSSMVIMVCGLLELIESGL
                     LDKTEKNLYQSAVWKIMRQLKERYATTEEEDGFLTQSVYNKPKNNGVNTPCIWGDYYY
                     LEALVRMTSNWSSYW"
     gene            complement(10887..12821)
                     /locus_tag="LLC22_000401"
     CDS             complement(10887..12821)
                     /locus_tag="LLC22_000401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5433707.1"
                     /translation="MILLQANQIARHFGAEVLFENIHLEISTGARVALVGRNGAGKST
                     LLKIIAGIEAPDEGKIAKNKTATLGYLAQDTGLDSNETVWNEMLKAFEQVRQMEERMR
                     ELEIFISEGTPDTPAYSSYLKEYDRLQHDFSDRNGYGYENEIRSVLHGFKFDSSFYDQ
                     KIDTLSGGQRTRLALARMLLQHPDILILDEPTNHLDIETLSWLENYLQSYTGALLIVS
                     HDRYFLDKVVNEVYELSRRKMRHYKGNYSKYLDLKAEQLASEWKAYEKQQTEIHKLED
                     FVARNLVRASTTKRAQSRRKTLEKMDRLDRPQGDEKQANFLFSIEKPSGNVVLQIEDA
                     AIGYDNVTLSEPINLDIRRQEAIALVGPNGIGKSTLLKSIIHQIPFIRGKETLGTNVT
                     IGYYDQGQADLHTNKTILAELWDEHPTTPEKEIRSALGAFLFSGEDVEKPIPLLSGGE
                     KARVALAKLAMNKENFLILDEPTNHLDIDNKEVLENALIDYDGTLLFVSHDRYFINRI
                     ATKVVELSENGSKVYLGDYDYYLEKKQEEEEIAELLAQDEPESAPAPTNKSDYYQSKE
                     QQKLIRSLQRKITQVEEEMARIDEWIDQLEQEMVAPENLEDHVKLNELNQDLEAARQD
                     QETKLTEWEELSLELEEYEN"
     gene            13047..13703
                     /locus_tag="LLC22_000402"
     CDS             13047..13703
                     /locus_tag="LLC22_000402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBK5433708.1"
                     /translation="MKDHIIPKATAKRLPLYYRYLRILNNAGKKKVSSTELSEAVQVD
                     SATIRRDFSYFGELGKRGYGYDVEDLMHFFAKTLNDDQLTNVALIGVGNLGSALLKYK
                     FHQSNSIRISCAFDVNEEIVGRIVDGIPVYPMEDMSEQIKIQQIEVAILTIPAERAQE
                     VVNQLTEAGIKGILNFTAARLNAPSDVLIQNVDLTNELQTLIYFLHSDANAHSENTAE
                     "
     gene            complement(13777..14130)
                     /locus_tag="LLC22_000403"
     CDS             complement(13777..14130)
                     /locus_tag="LLC22_000403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBK5433709.1"
                     /translation="MKQTTNLTEVQDILQQSSVAVIYLSMPNCSVCHAVRPRLEELLT
                     HYDIPALHLDAFETPEVASKFEVLTAPVVLIFHQGKEVFRQARFIDFKKIRYLLDELT
                     AEDDSLSYEEIFRTK"
     gene            14322..15251
                     /locus_tag="LLC22_000404"
     CDS             14322..15251
                     /locus_tag="LLC22_000404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306129.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="permease"
                     /protein_id="HBK5433710.1"
                     /translation="MFSFIPNSVLQMSTIFLSIVIEALPFVLLGCLISGALQVFLTPE
                     RVKRWLPENRIFSIFTGSILGFFFPSCECGIVPIVHQFVKKGVPVHTAFAFMLTAPII
                     NPIVIFSTFIAFGNSWQMASWRVIGSFFVALVIGVWLAYFQKDAVLKEKITSKVAENH
                     HHHVHEEEQSEKNEPKNQLIHQTGHVLTHSIDEFFDTGRYLIIGGLIAAAMQTYLPTR
                     IMLTLGSTKILAIIIMLLLAFTMSLCSEADAFIGSSLLSLFGTAPVAAFLVFGPMVDI
                     KNLLMMKRYFTGRFILSLIGLIALSVIGFTLFI"
     gene            15262..16098
                     /locus_tag="LLC22_000405"
     CDS             15262..16098
                     /locus_tag="LLC22_000405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR03943 family protein"
                     /protein_id="HBK5433711.1"
                     /translation="MLRFLILSGYFELMMYLQVSGKLDQYINVHYRYLAILSMILSAL
                     LALVQLYLWVKNGKAEEKAHEHDHDHGLSKPYQRGIAYVLLALPVIVGTLFPTVSLDT
                     TIVEAKGFNFPVSKESVGDPEMQTQYLKPDTSIYFNKSDYLDQMNELKEKYGDKQTIK
                     ITDENYLEVMELIYNYPSEFIGKKISYEGFVYQTPNDSNTDIFLFRFGIIHCVADSGV
                     FGLLTHMPEGVTVKNDEWYKIEGTIQSDYYQPFKREIPSVVVTNAEKVSAPKNQYVYR
                     SF"
     gene            16346..17122
                     /locus_tag="LLC22_000406"
     CDS             16346..17122
                     /locus_tag="LLC22_000406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5433712.1"
                     /translation="MVTRIFILDDSLVFEKMLVEILEESRILLSPWKFEIVQGLNVIQ
                     FVEFIKNNEIYSSDIFFLDIDLNAYYSGIELGEMLREKNEKCKIVYLTSHPNKAITVI
                     NRKITPSGYLIKEFTYEKNKKSIQSYLLKEKENYPVQHATKKRWTTVRYGNSDHYIHY
                     DEILYLMSMPGYKNKIGLVLKDEEILVNGTIKKYKKSLEYEYLCKDLKAYIINTENIT
                     SISRVNEIVTFANGEQLEMGKRSIDKLKNFMQEKIENESF"
     gene            17298..18041
                     /locus_tag="LLC22_000407"
     CDS             17298..18041
                     /locus_tag="LLC22_000407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5433713.1"
                     /translation="MIEFINVSKSYGKKQALKDLSLSIRQGEIFGFLGHNGAGKSTTI
                     KSLVSIIEPSSGTILVDGMKLTENRLSIKQKIGYVPDSPDIFLQLTAGEYWDLISAAY
                     ELDTQKKEKRLAELTALFDMYSHQNETIASFSHGMRQKTILIGTLLPDPDIWVLDEPL
                     QGLDPQAAFDLKEMMKAHAAKGKTVIFSTHVLDTAQQLCDKLAILKKGELIYQGAVSE
                     LLNGSPDETLEKIYLKMAGRQATGDGPYV"
     gene            18034..19614
                     /locus_tag="LLC22_000408"
     CDS             18034..19614
                     /locus_tag="LLC22_000408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter"
                     /protein_id="HBK5433714.1"
                     /translation="MYKRQLLELIRVNLLYVNPQLTNKAREKGKKGKRLTIYLLSQNL
                     FSGLIFLLIYGFAMFAMNFVKLPGFFTYYVALFGMLGLTQSISVIYNIFFEGNDLQVF
                     LPLPFGQEQVFSAKILVVALTIIPFVFPLLVMFILTGWRADLGILLTIIISILLFSLF
                     LIILFCLASLIVFGLARTAVFKKHRKTVSSILLGSSMLIAFAGIMWMNHQTGTIENEL
                     TDRHPISILLPFYDAASQPLSQQGLLGWGILAITALGFFLAVKQLIVPKLTEQLTDSN
                     SEFKIKRTHKKNQNVHQLLFSYNAQLVKEPNLIMQVLSSSLLTPIIFILAFALGGEIK
                     LTDLDNKLIGVVFLVGIALAFLTVNQTSFISNLISLDQENFLFIRSLPISMNQYLKEK
                     FRFGWILQSFLTGGIALLSGLSFQLPLFFIPSLLFGSLFGCYLLSLRYFARDYRLLLL
                     NWTNINQLFNRGSGSLGLVATMMGSLIISIILIVLYGMLALFYPFWLVNIPVIGLVLI
                     LSALWIVYYQRTFWKKFE"
     gene            complement(19865..20344)
                     /locus_tag="LLC22_000409"
     CDS             complement(19865..20344)
                     /locus_tag="LLC22_000409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK5433715.1"
                     /translation="MGTIFIQFSFSFLATAAFAVITNVPRRSLICCGLSGAFGWMIYW
                     ICVQIGGSAAFGSLLGSLGVAFISDLFSKRLKMPVTIFNIPGMVPLVPGGLAYQAVRN
                     LVTESYREAAHYAVQAIMIAGAIALGLVLSEVFNHNIRNFKVKRDAIMMKRKKRLFK"
     gene            complement(20360..21112)
                     /locus_tag="LLC22_000410"
     CDS             complement(20360..21112)
                     /locus_tag="LLC22_000410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine/serine exporter family protein"
                     /protein_id="HBK5433716.1"
                     /translation="MTGKELDLLLDTCLLAGKIMMESNAEMYRVEDTMSRIALASGNF
                     RLVSYVTQTGLFIGLDRTSTIRMEQITNRSINLEKVVKVNDLSRKYVASELTLEELYC
                     ELQAIDRDRSFFPVWLQIVSAAVISGTIMVLFGGKMTDLPVTLVIGGLGYAAYLYSLK
                     FFRIKFLSEFLSSLLIGIAAIYSVRFGLGSNQDLIIIGCVMPLVPGVQITNAIRDLLA
                     GHYVSGVSRGTEAMMTATMIGFAIAFIFQLFY"
     gene            21229..21299
                     /locus_tag="LLC22_000411"
     tRNA            21229..21299
                     /locus_tag="LLC22_000411"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:21261..21263,aa:Gly,seq:ccc)
     gene            21660..22385
                     /locus_tag="LLC22_000412"
     CDS             21660..22385
                     /locus_tag="LLC22_000412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA non-specific endonuclease"
                     /protein_id="HBK5433717.1"
                     /translation="MSKKTTKAIVGIVAAVIAGAFGVSTTQKDSDIFQQITTIFDSTP
                     QASQVADVPEYDGKHQEIEINGNQPEFTKEDLSLSKGTWESYSNIDKLNRVGQANAML
                     GKDLFPTEKREPLYIDPTGWKQKKLSDGQWLYNRSHLIGFQLTGQNNNIKNLMTGTRS
                     LNAPYMLAHENDIAAYIKETNHHVRYRVTPHFEGNELVARGVQLEAESIEDKKIEFNV
                     FIYNVQDGYTINYETGQATKTKN"
     gene            22640..22906
                     /locus_tag="LLC22_000413"
     CDS             22640..22906
                     /locus_tag="LLC22_000413"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IreB family regulatory phosphoprotein"
                     /protein_id="HBK5433718.1"
                     /translation="MGFTDETVRFGFDDSRKKEVSETLAIVYRALEEKGYNPINQIVG
                     YLLSGDPAYIPRYRDARNLIRRHERDEIMEVIVKDYLSNHGVNL"
     gene            22903..23334
                     /gene="ruvX"
                     /locus_tag="LLC22_000414"
     CDS             22903..23334
                     /gene="ruvX"
                     /locus_tag="LLC22_000414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction resolvase RuvX"
                     /protein_id="HBK5433719.1"
                     /translation="MRVMGLDVGSKTVGVAISDPFGWTAQGVEIIRINEAEEEFGFDR
                     LKELVAQYEVDRFVVGLPKNMNNSIGPRAEASMSYGEKIKELFSLPVDYQDERLTTVQ
                     AERMLVEQANTSRAKRKKVIDKLAAVMILQNYLDGSGKQLF"
     gene            23359..23664
                     /locus_tag="LLC22_000415"
     CDS             23359..23664
                     /locus_tag="LLC22_000415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002419177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1292 domain-containing protein"
                     /protein_id="HBK5433720.1"
                     /translation="MTEHNHSHDHEGHEHITLVDDQGNETLYEILLTVDGQEEFGRNY
                     VLLYPAGVSEDEDVELQAYAYIENEDGTEGELEQIETDAEWDMIEEVFNTFMAEEEE"
     gene            complement(23745..24890)
                     /locus_tag="LLC22_000416"
     CDS             complement(23745..24890)
                     /locus_tag="LLC22_000416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5433721.1"
                     /translation="MATFKQYETKKGKFWLYEAYLGMNKMTGKPDKVRRRGYKTKKEA
                     QLALSRLQVDYDKNGIKKANNETFKEVYDLWLETYKTTVREATFMKTEIKFRKWILPK
                     YGNLRVNEVTVKKAQQIVNSWAETTDQYKVLHSTSKRIFSYAINLGIIETNPLDNVLM
                     PKRTTTKHKEKVKVYSKEQLITLFDYLNSKPETYRNDFDKTLLRFLFYSGVRISEALA
                     LNWSDIDFQENTVTINKTLSQSKNGYKISDPKTDCSAGVLPLDERTISILKKWQINQR
                     KYMLTLGVTDPTMIFCGIYKELITHHAIYARLITICEKAMVPFLGVHVARHTHASMLL
                     DAGATMVEVQTRLRHTKISQTIDCYGHLAKETKEKTVEKLVQHLNID"
     gene            complement(24951..25598)
                     /locus_tag="LLC22_000417"
     CDS             complement(24951..25598)
                     /locus_tag="LLC22_000417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5433722.1"
                     /translation="MNGGENVARKKYPEAVETGQRIRLARIEKGLSMEQLGGKLSPPA
                     SKGAVSNWENGYNLPNNTRLKQLSKVLDVSTTYLLNGSYTLRDMHMMPEIKRNVLEKQ
                     LKKTIEKNNSIIDSNLSNAINNIEEDNLTVSQKIYLTNAIKYLKTGSRIEFPDGSTPI
                     AYLAALLNTLLRYDSLINDSEKNTDEKKEYQEFYENDLLKEFTALVTELNKHYSK"
     gene            25792..26085
                     /locus_tag="LLC22_000418"
     CDS             25792..26085
                     /locus_tag="LLC22_000418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433723.1"
                     /translation="MELKIDKLTLDDPAFKIIDDRVVQQVEQTQGTLLSLLEKKYQFP
                     KYMNKAQAAKYMNVSYNTMMQKYVPNGLKLIIVDGVVRISQDECDRFMEEYQK"
     gene            26129..26440
                     /locus_tag="LLC22_000419"
     CDS             26129..26440
                     /locus_tag="LLC22_000419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433724.1"
                     /translation="MESTQNKAIEKVLSTILTEDTAAELANLEGKALEETFECLYEQM
                     DYQKLLPQEPTVSGVLRGLNDLVQAEFKERLSIEEYQEILYQQVELLASLLGLELEDV
                     E"
     gene            26437..27061
                     /locus_tag="LLC22_000420"
                     /pseudo
     CDS             26437..27061
                     /locus_tag="LLC22_000420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350005.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phage repressor protein"
     gene            27202..27360
                     /locus_tag="LLC22_000421"
     CDS             27202..27360
                     /locus_tag="LLC22_000421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433725.1"
                     /translation="MKRNLIIGSILIGGIFGLLPLIAKIAIFAGLALYLFTAYDEYDY
                     QLRTGGHK"
     gene            27361..27723
                     /locus_tag="LLC22_000422"
     CDS             27361..27723
                     /locus_tag="LLC22_000422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433726.1"
                     /translation="MYKTKLLNQLDSLELEEINQGIAELENNIGKTYFGNSFNEKLTV
                     LYVLKKHAEHKIICREINELKNQILTAWLNITDMQEARVKTFNTWVKYQNQLKGAEFV
                     RDGLKYELEQLKLMEVSE"
     gene            27760..28608
                     /locus_tag="LLC22_000423"
     CDS             27760..28608
                     /locus_tag="LLC22_000423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional DNA primase/polymerase"
                     /protein_id="HBK5433727.1"
                     /translation="MANNYQAATELQKSGWSIYPLSPGTKIPIKGSSGWNDATNDSNQ
                     INEWWTEDATRNIGLMLEDHQMVVVDLDQHSETRNGVENYKKLASMYDPFPSTYTEIT
                     PGKGIHFFFKIPDGVIIQQETGAFADIFGRDDKGKSLSGIDIITKGVPIAPTMIISRS
                     VGRAYEPIENVSLNNIAPAPDWLVNLLLKKPQEIKTQYRPVAKTGTAKKLDMIVQGAG
                     EGSRNDHLTKLCGWLLWHGVDNQTLAELIYTANAYNEPPLKDKEVNQIIRSMIKKDLR
                     GKAHGS"
     gene            28598..30073
                     /locus_tag="LLC22_000424"
     CDS             28598..30073
                     /locus_tag="LLC22_000424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase"
                     /protein_id="HBK5433728.1"
                     /translation="MAHKHKLDSILDFPEASEREDNIIELKTWMSRLRCNKDDQIKSN
                     SVVNAELILTNDSNLAGTIAYNEFSGYIHLLKDSPWINRTAGEWEDSFEDALTAYIEE
                     NYNVVFDDNKIHKAVVNVARKNVFNPVKERIEKVKWDQQPRLETLFIDLLGVDDNLYT
                     REVTKRWIVGSVARIYKPGIKFEIVPVLDGPQGIGKSTVPALLYTDDFFTDSLDSLGE
                     KKDDYMQLQGNVIIELGELSSMNKTKIEQIKNFISAKIDKIRPPYGRNVIAWARQCVF
                     IGTSNDGQYLKDDTGNRRFYPLPCKNKPKMNPFKTKDEYFLQVLAEAKVLFDKGQRIY
                     FSPDEDKEVLEIAKDYQEDAKMENPIKEAITKYLEMEIPYKWEEAPAWARRSYYQNYP
                     DSKCNEKNLQHFYNGATMQQEFYLVDSVLTADILEAVFDKQAKDLLNGRSDAETKKIA
                     LIISSIPGWERKQLPKRNKRRGFYNKSNAYENKNRAGKYKK"
     gene            30339..30746
                     /locus_tag="LLC22_000425"
     CDS             30339..30746
                     /locus_tag="LLC22_000425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3206 domain-containing protein"
                     /protein_id="HBK5433729.1"
                     /translation="MLNIISTNKAPNFQYTDEMDRFLMNTLAFSVGLVTEDYSTFDPE
                     VLKIMEEEPDWLQESVAWCQSLVVGSLVDSGNYDDTGELMDEFNCLLNLYDRARQREL
                     TSNEDNLFLNIHDKFLALLLTDDELITNLLEVE"
     gene            30749..30964
                     /locus_tag="LLC22_000426"
     CDS             30749..30964
                     /locus_tag="LLC22_000426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433730.1"
                     /translation="MHMESIRYFDGEKHIEYSNTQEDVDFISFEEDKITKVNFKDGTC
                     LKIVSPYIEYKSKWEQDDSDERDRFGW"
     gene            30968..31348
                     /locus_tag="LLC22_000427"
     CDS             30968..31348
                     /locus_tag="LLC22_000427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBK5433731.1"
                     /translation="MAVKKQCNHAGCKTLIDYRQKYCGKHKAKQTAIKREERKQSEGK
                     YFQFYQSRTWRKASYLYRLNHPVCEDCLEEGLIRKADVVDHKIELKDDWNRRLDETNF
                     RSLCHAHHNSKTANERQRREKSTL"
     gene            31482..31637
                     /locus_tag="LLC22_000428"
     CDS             31482..31637
                     /locus_tag="LLC22_000428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010780558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2292 domain-containing protein"
                     /protein_id="HBK5433732.1"
                     /translation="MKVGDLLKNTIVITDKTGKQRTIELPHFGQVTIQMQNGKIIYID
                     KLDKEKF"
     gene            31706..32179
                     /locus_tag="LLC22_000429"
     CDS             31706..32179
                     /locus_tag="LLC22_000429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase small subunit P27 family"
                     /protein_id="HBK5433733.1"
                     /translation="MGHPKILHDTKGNISSEEKAIRVDAREELFKQQPLINITPPDWM
                     AASARSEWNRIVPTLKKDYPLSEADYGSLVAYCLAFARMKTAEAEIRKSGTFITCENG
                     VKKANPAVRVQSQAMSDLKKQATSLGMTLESRSKLALNKVKNDEPEDPFKELMNS"
     gene            32176..33870
                     /locus_tag="LLC22_000430"
     CDS             32176..33870
                     /locus_tag="LLC22_000430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBK5433734.1"
                     /translation="MNDYIEKVLSGKLIAPKKIIQACERHISDLERSKSDSFPYVFDE
                     EQATKAIKFIELLPSTDGKAIKMLGFQKFILGSLYGWRTKEGNYRRFNRAFTSMSRKN
                     GKTYIASGMAANALIMEQEPAEARQVLFVSNALKQAKLGYDMLSNSLRNVVKSSKFLR
                     PQLKIMNSKIQHLPSNSFAMALASETSTLDGFAPTTAILDEWHEAKTRKTYNVIKSGM
                     TQQKNGLLCVISTAGLDLNVPMYEEYLLLDRVLKGEEQADRYFIAIWELDDPEEIHDQ
                     EKWIKANPIFESEEIKKVMIPTIQDDVNLALKQNNLNSVLVKNFNLWRQASEDSYMIA
                     EDWQATEVEPQDITGKPVYIGVDLSKTDDLTSVSWIVPLDNGELYCDSHSFVATKYGL
                     QDKEKRDGLPYRELEKAGECSITQLESGIVDYDQVFQFIQDLIQENDLECMGICYDPY
                     NANSLISKAEKANYPMLEVRQGTITLNVPTRTFREQVYEGNVIHNKNTILTHAVNNAI
                     LKTDNNGIQINKSKNSNKIDPIAALINAYVFAMDYFTTTEGAKADNEFYTSEEFSF"
     gene            33836..34021
                     /locus_tag="LLC22_000431"
     CDS             33836..34021
                     /locus_tag="LLC22_000431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433735.1"
                     /translation="MNFIQVKNFLSNYIHTVLLLLGLVCVLVAITLLTNVYYGLLALG
                     IVLIGVAVMLNTEQKGG"
     gene            34025..35200
                     /locus_tag="LLC22_000432"
     CDS             34025..35200
                     /locus_tag="LLC22_000432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK5433736.1"
                     /translation="MAFFKARQNTTGDPFLQHVVSIQSDDYTTSFTSVRALRNSDVFA
                     AVRIIASDIASSPIQLVKNNMPQADNELVKLLNEKPNSEMDGWHLKFALAVNMLLNGN
                     SFAEIKRNGEKVEEIHLLPNSSVTVTQLDNGTLSYQIGDKKRRVKSSDILHFKYFTQD
                     GLTGLPPLYALRDELKIQQAGNRTLHNFFTRGVSGSGILKVHKSDLDGSAKNAIREKF
                     EEANGSSSGDNALRTIILDETMDYKTLEINTDVLKLINSNDWNTKQIAKAFGVPIERL
                     GVENEHSSTVQSNLQYIQSTLIHYFNVFVSELDTKLETNIRFNSDQLLETDPETKVKN
                     VLDQVKGSLLTINEGRSKMGLPPMDGGDRLLASLNFTYLDTLEKYQLKEQEGVTPVE"
     gene            35193..36716
                     /locus_tag="LLC22_000433"
     CDS             35193..36716
                     /locus_tag="LLC22_000433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBK5433737.1"
                     /translation="MNNEEEKEKRLTEEAELTADSPKVEKENEKQPTDGKTISGYALK
                     FGQPSKDLGGFVEVITPEALKEVDLSNVFLLYGHDYSKPLASVKAGTLKLNVDDTGLH
                     FEAELTDTTYSNDVYENISKGVVDSMSFGFVLGLDSFDKKEDGTIERSIDKIKALNEI
                     SVVTVPAYDSSNVQVNKRSYESFMSNNQAKQTNNSLESTSKAQKESNNMEKTLIDNEK
                     TELRGYEEYIRSQGEVRDGVTTVNAAAVVPEEVIGEVFDLKRSNYNLAQYATVKTVSN
                     GQGKYPVATNQQAVLATKAELAEIGDIDAEMFTSVDYKVETRAGKIALSNEVVEDSAV
                     NIVQEVKDQLAKLVENTDNKHIMDLLKTFTKKTAATLDDLKQLYNVALDPALNKMVIL
                     NQSGYYHLDTLKDSDGRYILQPDVTAPSGKSLFGMPVVLIADTLFANPKAGTFPMIMG
                     DIAQSIFVARRNQVTTQWEKFDYYSQGLAVIVRNDYKKIDQNASVYIEFTPVVTPKV"
     gene            36772..37056
                     /locus_tag="LLC22_000434"
     CDS             36772..37056
                     /locus_tag="LLC22_000434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBK5433738.1"
                     /translation="MVILDSIKKSMRIDHTIDDDFIQQLIDTAGEYIKSAIDSSATDK
                     DMDNYQQFDLAVSLLTQHWYLNRQEASSERIPVTVQALVQQMRGAYYANH"
     gene            37043..37378
                     /locus_tag="LLC22_000435"
     CDS             37043..37378
                     /locus_tag="LLC22_000435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBK5433739.1"
                     /translation="MPIIKNVNELTERVKFKKTKRVKDEDGQMVDSEETVFECWANVR
                     SQMLKDVLASVGTILEGTLTFIIRYDQDYELTNDMKVAWKNKSYKIISINEGTAFKDY
                     TTIIAKQIS"
     gene            37673..38299
                     /locus_tag="LLC22_000436"
     CDS             37673..38299
                     /locus_tag="LLC22_000436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296481.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433740.1"
                     /translation="MDKAEFTNFYWKYYLHLENEFINTTDFVMLDENNFKTFSIEYQK
                     LLLAIGSECEIIFKELCGFDSSSNKSITDFKAVIKSSELMCLDNGVRVMNSLTLTSLK
                     PFGDGWPEDTPDWWKIYNRVKHGRSSNYKEANLENVLYALASLYLLEEYLHKKVILEG
                     EVDFISPESNLFTLSWERKHSSMQKVTFEKVDSNYVAPLIDFKEQEEI"
     gene            39041..39877
                     /locus_tag="LLC22_000437"
     CDS             39041..39877
                     /locus_tag="LLC22_000437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfite exporter TauE/SafE family protein"
                     /protein_id="HBK5433741.1"
                     /translation="MIGLIYFVVIVLANTVGAISGMGGGVLIKPILDLIGAHSVAGIS
                     FYSTVAVFTMSIVSTVRQVSSGKSLNWQIVGWVSSGAVVGGVVGNIVFEVFLQLFENE
                     KHVQLIQIFLTVLTLVFAFFYTKHHQPKFHLTSWTWYLICGGVLGFLASFLGIGGGPV
                     NVSLLMLMFALPIKEATLYSLSTIFFSQLAKLVTIALTSSFMRFDLSMLFYVIPAAVI
                     GGLWGARFSRVLSPKKVTFIFQVIVLVVLLVNCYNAFVILQTLGESRLTQVKITETYC
                     SK"
     gene            39942..40376
                     /locus_tag="LLC22_000438"
     CDS             39942..40376
                     /locus_tag="LLC22_000438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5433742.1"
                     /translation="MLREMRLEDAEALREINADQLGYDIPLTVTVRQMKKLLKEPEKN
                     FFLVYEDPTSKKAAGYVQAESYESIFSDPMFNIMALAVSKYAEKRGIGKALMTGVEEE
                     AKKRGITTIRLNSAEYRVEAHQFYEHIGYHSDKMQKRFLKIL"
     gene            complement(40444..41766)
                     /locus_tag="LLC22_000439"
     CDS             complement(40444..41766)
                     /locus_tag="LLC22_000439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBK5433743.1"
                     /translation="MAQKTTTATAVEEKKKEGFWSTKITGVSLPLYLIMVLVLIIAMA
                     LGKLPTNMIGPIAVLVIFGNLFHFIGTKIPIVKSYLGGGSVFAIFASAAIATFGILPE
                     YVVKSTENFVSNMGFWDFYIAALITGSILGMNRNLLMKASVRFIPVALISMVVSFFAV
                     GLVGMLIGNGFANSVLYISLPAMAGGVGAGAVPLSTIYANVLGTDASSIISRLIPATA
                     MTNVLAIIGAALVARAGQSMPKFNGNGKLMEKGDLGDGKPRTVKPSIPQLGVGLMVSL
                     TFFILGQIGNYFVPKVHAYAFMIIIVVICKIANLLPEYYEDAAIMFNNLIVKNLTAAV
                     LAGIGIALLNLNVLASALTWQFVVLCLTSVIAISVVSGFVGRLFGLYPIESTITAGLC
                     NNSMGGTGNVAVLSAANRMELIAFAQMGNRLGGAIVLIISGFLMQLLS"
     gene            complement(41920..43560)
                     /locus_tag="LLC22_000440"
     CDS             complement(41920..43560)
                     /locus_tag="LLC22_000440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345286.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent malic enzyme"
                     /protein_id="HBK5433744.1"
                     /translation="MLTGLNLLNNPFLNKGTAFTKEERAKYGITGMLPSTVQTLEQQS
                     VQAYGQYLSKQTDLEKRIFLMNLFNTNRTLFYKLMGEHLVEFMPVVYDPVVADSIEQY
                     NEIFLKPQDAAFLSIDEPENIKASLKNAADGRDIRLIVVTDAEGILGMGDWGVNGVDI
                     AIGKLMVYTAAAGINPAQVLPVSIDAGTNNEELLNNPLYLGNRHARVEGETYYEFIDQ
                     FVQSATELFPELLLHWEDFGRGNAAAILEKYEDQITTFNDDIQGTGIVVLAGVLGGLN
                     ISGEQLKDQIILTFGAGTAGVGIANILLDEMIRQGVPEEEARQHFYQVDKQGLLFEDT
                     EGLTPGQIPFARKRSDFTNADELTNLEAVVKAIHPTIMIGTSTQPGAFTEEIVKEMAA
                     HTPRPIIMPLSNPTKLAEAKAKDLIEWTDGKALVGTGIPAADVEYNGVTYQIGQANNA
                     LMYPGLGLGLIASTATRVNAEIISQASRALGGIVDVTKPGAAILPPVAKITEFSQTIA
                     ETVAKSVVAQNLNREEITDIKEAVESAKWVPEYKSLED"
     gene            43890..44360
                     /locus_tag="LLC22_000441"
     CDS             43890..44360
                     /locus_tag="LLC22_000441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4809 family protein"
                     /protein_id="HBK5433745.1"
                     /translation="MKEVQLIRKSELSEGGCNACGVVEATSYTLKLDSNQAIISELTV
                     GGLVDSLALAEGFTGEDIYEMFSEVRQLKKGEKCIEVHHESPNVRFKRGDNEMIFKNH
                     VSDHTELYEIVNQILSGIFELGPYEFKEENGNPKLNEEWQETIETQRNNPHLFQ"
     gene            44989..46092
                     /locus_tag="LLC22_000442"
     CDS             44989..46092
                     /locus_tag="LLC22_000442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBK5433746.1"
                     /translation="MEKTYQAGTNEGIVDFINMEDLEIAASQVIPAGGYGYISSGAGD
                     LFTYQENERAFNHRLIIPHVLRDVELPDTTTHFDEEMLTAPIIMAPVAAHGLAHVKAE
                     KASAKGVADFGTIYTASSYASCTLEEIREAGGEKAPQWFQFYMSKDNGINLDILEVAK
                     RNGAKAIVLTADATVGGNRETDRRNGFTFPLPMPIVQAYQSGVGQTMDAVYKSSKQKL
                     SPKDVEFIAAHSDLPVYVKGVQSEEDVYRSLESGAGGIWVSNHGGRQLDGGPAAFDSL
                     QYVAEAVDKRVPIVFDSGVRRGQHVFKAIASGADLVAIGRPVIYGLSLGGSTGVHQVF
                     DFFKTELEMVMQLAGTQTVEDIKKIKLRENRFI"
     gene            46376..47056
                     /locus_tag="LLC22_000443"
     CDS             46376..47056
                     /locus_tag="LLC22_000443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBK5433747.1"
                     /translation="MKKNMIGTLLLSTLLLGGLATPAFAEGQATSKGDITFTEPTNTV
                     EPLNPTDPSKPVEPADPENPATGQTGSLTLDVVPELPFGTHEIESGTKTYQVDASKND
                     TPYLQVSDRRGVGADGQAQGWNVTVSVSDFVNGSQVLQGAELDFGTSTVKSTSDNEST
                     GPTSQTVTGLSKASAATPIFTAAKDQGLGTWLSVYDPANITLKVPKAAAGTFTADLTW
                     NLVAGPVA"
     gene            47146..48180
                     /locus_tag="LLC22_000444"
     CDS             47146..48180
                     /locus_tag="LLC22_000444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBK5433748.1"
                     /translation="MNQSKRLFVSFFSILSLFFIFPSISQAKDSAGDFGIKPVFPENQ
                     IDKAIGYFDLLVAPEQNQTLEVIISNSSDEERTFEVSVNPAVTSDGGTIDYSQKNPTL
                     DETLPFDVRDVLLIAKKEINVSAHAETTIPIEVKIPAKSFKGRVLAGIHVSPKEEAET
                     ENATEGAQIKNRIAYNLAVVLQESQETIEPDLKLLSGDLDEVNAKPTVQLRFQNPQPR
                     IISNLIFTSKIFYENQLYIENTSNEFLVAPNSNFHLNLDLAGDKAKAGDYRAEIIAKS
                     GDSNEWRFTQNFTIKKEKAQKVNENSVFAVQEQSFPWLYAGLVAAVLVLWLILLFLWV
                     HKKKKKGETT"
     gene            48194..48529
                     /locus_tag="LLC22_000445"
     CDS             48194..48529
                     /locus_tag="LLC22_000445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433749.1"
                     /translation="MKTSILLGGIIASLLFFSWQEPVQADTKSSGTITFYDLSPVPHP
                     SGSVNGASKQQTQLPIYKESNQHGVFPETNEEKIRFLYLIIGIELWLLAWLLLWRRKE
                     KEDEHVATK"
     gene            48513..50975
                     /locus_tag="LLC22_000446"
     CDS             48513..50975
                     /locus_tag="LLC22_000446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326300.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433750.1"
                     /translation="MLLQNKFSFFRSFFFTSLFVLSIFIFSPSAEAVGATPPAISYDP
                     YTYENIVPPNGGRSAVNGGKLVQLTGANQLPKLTATYLNDGSNDPWKGGTVRFHWESH
                     VKLTNVLDLVNITAQGFAFVAIINLPEHVSSSDVLKAIDWNNAYLYIAGAPIKVTSGS
                     LLSAGSHTLRFGMGSWDTNTLLADIIAIITRGIPLQFDVTANVAKMTENGDKYDTSPN
                     KILTKGKLQPSMSKKAVFSVDFYDSNNIIQDRMFNSILAPAAGRFYPKLTGGNLNPGA
                     YAFSASAEINTWNSYISTSDSTGKYNTFADTTEYVDGNNQNLPGSTNSRTLTMGLTEG
                     RFDQLPFSRFDRVVNYFTGKNVTQGAILTHTPASTSGLNQTANIVYSGKDAQGGLLSP
                     VALKVLEQYKLDGTVLPTNLTADSQWGKLLSSASYQVTANWSATELKKGSIHYRLYSK
                     GTQKLATGWTDQLFQTIQSNNGGVNTATSTLPALASGQYYFDYRLVDDVLTNMYPSFA
                     YKWQSEQAGITTLPQITVANFPSVSADSQLKNLSRQPETGDPLSALSGDTIQENVTFT
                     LTKSGDAITDKKITISLPENTTYINGSLKLNGTTIADTGIQQGVSVPADLLSKIGDTI
                     HLTYNYQLNTVDTSVQSVSILTKAAVLSSNITLADGAKLPNPVVQTSAKTILVPKQEL
                     TLVNVPDDFTFGNDLPKPLKTSYYEAKGDFSFDVRDTRLPSTSPWQLTGTLTSLFKND
                     QGQELSGTKLYFNHSGSKQLIQQGQNTLIYESDGTAKGEVLVDFPDTDGLLLEVNSST
                     NAQPGATYQGMVTWELTAGPTS"
     gene            51031..52590
                     /locus_tag="LLC22_000447"
     CDS             51031..52590
                     /locus_tag="LLC22_000447"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433751.1"
                     /translation="MRRKLLLLKSEMLGGVDLELFSLLEKNEQRQIKLFQLLLEEKGE
                     ISVNNVLTRLSVDRATLKEDLFYLQANLENIKQLEIVIQEGNILLIRHGNIAAVDVYY
                     HCYLRYSTKYQILLYLLENGSFDRQKLVMELNISSATLSRRVKELNDSLNEFHLKIKS
                     GRLTGPESQICYFYFQLFWFGRPYLENKKEYSDLSGNTFLDLLQKEFSFTITEEGRLK
                     FEIWLSIMKKRMRCTKKSKPDYSNLPVGLFQTTQFLLDLHTFLTRYFFQYAFPWNQNE
                     TLVFYLFMISNFTLDTHNSHVQEFLISEKYKDDVVAQLNRTFKQSIEEYFSFYVFPEE
                     ISQKIALTVMQNHAHFAYFRGWMNIFGQEGLKQRLTEVEDKQFLVLCERLVRQTFAIV
                     DFTEVDEENARFELFARYASILRTLIKQLELRLQIAYDLPYERLMADIVKEIIQEQLL
                     NTIKYDLVEYEKEKQYDIILTSQLKEYPSQKSAKVFVFTSNEYNYDFPYLNQFLKECY
                     LEKLNLRMNKT"
     gene            52587..53951
                     /locus_tag="LLC22_000448"
     CDS             52587..53951
                     /locus_tag="LLC22_000448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5433752.1"
                     /translation="MKIVIIGASHAGITAALNLRKLQPKAEVLLIDEDHKDGLGYVSN
                     GINLYLKGKIRSLAEVAHNMRTLQESGAKLITEWRVTELDPDKHQLILASKEGKNETI
                     TYDKLIVATGSSPVTLYKQIEAENVYTYKNLVQSKQVLAALKEAKEVVIFGAGYIGLE
                     LADALRNKGYIIHLVDYMPNVLSRYFDKDMINSFQNQLQTKQINFYPNEFLIDWKKSE
                     EKVVSVQLLSQAIKADMVIFSAQTRPNTTLLKEKVALYEDETVIVNEYLQTSDPDIYA
                     IGDIVPVSFDKNKRHLFLPLVTRAVHMARAVALTLSGQPTAYDLRQKITAAVIIDYFL
                     GTVGLTEDEAPFLEQNTGSCSGEFDLFPQYDEENKTVNAKLIYHPDTLEIIGGQLISQ
                     EFLLSDLNLLADIVKHKTTIPQLAVEDFGFLSEHTSRFHYLNELAFKVLAKRANSNRV
                     DKRL"
     gene            54122..55192
                     /locus_tag="LLC22_000449"
     CDS             54122..55192
                     /locus_tag="LLC22_000449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631334.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5433753.1"
                     /translation="MFLALNEIMHSKLRYALVAGVMFLIAYLVFFLTGLAYGLAQDNR
                     TAVDKWEADSIVLSKDANSNLGMSMITKKIAEEVEGGKVAYLAQTPGVVTSKDSTEEG
                     KINVSFFGIDKNQFIMPNLVEGKAFDNDDEAVGDISLKEEYGLAVGDTVKLSGSDKTF
                     KLTGFTDHAKFNVSPVLYTTINAYQEIRFEKEDTSENARINAIVVRGKISNLPEDLEQ
                     IKISKFINELPGYNAQVLTFGFMIGFLIVIAAIVIGIFIYVLTMQKINIFGVMKAQGI
                     TGGFIARSVVAQTFILSFVGILLGLLGTVGTSLVLPDAVPFQSNWLFFGVISLLMLVV
                     AVLGALFSVRTIVKIDPLKAIG"
     gene            55207..55875
                     /locus_tag="LLC22_000450"
     CDS             55207..55875
                     /locus_tag="LLC22_000450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5433754.1"
                     /translation="MKAIEFKEVEKSFQDGDQVVKALKETTMSIDKGEFVAIIGPSGS
                     GKSTFLTLAGGLQTPSSGSVFINDQEFSNQKESERVKLRFKEIGFILQASNLVPFLTV
                     KKQLLLVDKIKHEHRQKEAKELFEQLGVDKLINKYPEELSGGERQRVAIARALYNDPS
                     IILADEPTASLDSEKAREVVDILAKESKDKNKATIMVTHDTRLIDKCDRIFMMEDGVL
                     KEKE"
     gene            55895..56473
                     /locus_tag="LLC22_000451"
     CDS             55895..56473
                     /locus_tag="LLC22_000451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5433755.1"
                     /translation="MVHRYNKDTQQKILKEATDLFMSKGYLGTSTREIAQKVGITQPN
                     LYHYFGDKEKLYTAVLENHLKDVGKALREIVQTSETGFQVTLTKMAQFLIETHLVDLF
                     LMLHDLESNLSKETRDHLFFLWKKNYREPFEEIFSANQSVLRNGISKEIAARHFFLVL
                     APYITRSKRPVEEPLNVAQLIDLYLNGVLGEA"
     gene            56876..57787
                     /locus_tag="LLC22_000452"
     CDS             56876..57787
                     /locus_tag="LLC22_000452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5433756.1"
                     /translation="MKKIIGAFVFAIIIIIICFQIDVFGQKKIVGQTVSSTNSTVTKT
                     KESFDDTEQETLIKIGKNDRTLYTDDSLTTPLATINGGELAEFLSETKNAYQIKTNDG
                     YTGYLALEDGTKVTKNIQTKPEELSDAVIVLDPGHGGNDTGALSNDEQTEEKDITLST
                     AIKVKKALEDAGATVYLTHTTDELVQLGDICDYSEEKKADVFISLHADSTEYANEATG
                     ITTYYYYGQEETLAQTIADSFTDLPLDSRGISTGNYQVLRENLQPSILIEMGYMNNDS
                     DLKELVTDSYQQQIAASLTQALTTYFQ"
     gene            complement(58043..58960)
                     /locus_tag="LLC22_000453"
     CDS             complement(58043..58960)
                     /locus_tag="LLC22_000453"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HIII"
                     /protein_id="HBK5433757.1"
                     /translation="MSNVIIKATNDQLSQMKAYYRSYLLNKQIPYTSFAAKKDGTTIT
                     AYTSGKVMFQGTNAAIEADKWGEAQDKQAKPAKTASSLPKNISQLSVLGSDEVGNGSY
                     FGPLTVCAAYVKRDQLAELRKLGVRDSKELKDSQIIQLADILKKTIPYKLLVLSPEKY
                     NEIQPKYNAVRMKVALHNQAIHLLLKKIEPEKPEAILIDQFTPEANFKKYARLEKNQL
                     QEKLYFVTKGEQYHLAVAAASIISRASFLEELHKASAEAGITLPSGAGTKSDQVAAKL
                     LEKGGMPMLEKYAKLHFANTEKALKLLKK"
     gene            59162..59599
                     /gene="zapA"
                     /locus_tag="LLC22_000454"
     CDS             59162..59599
                     /gene="zapA"
                     /locus_tag="LLC22_000454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340190.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein ZapA"
                     /protein_id="HBK5433758.1"
                     /translation="MAHEKTRYKAVIANQTYTIIGRETKHHMDIVTKLINEQLAELKQ
                     LSPQMDNEQAAILMAVNALSDQLKKQERILELEEETAELKKKMIKFTELENRVKRIEA
                     IENEAREVLKENGQADHTIKNHVEAQQILNEKRKGQIKQKSSN"
     gene            59657..60205
                     /locus_tag="LLC22_000455"
     CDS             59657..60205
                     /locus_tag="LLC22_000455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CvpA family protein"
                     /protein_id="HBK5433759.1"
                     /translation="MLSLLILFLLLIAFFSGARRGFALQIIFAIGYVLSFIAAQHFYK
                     PLASHLELYIPYPAVTPTSKLAFFDQVFAFHLDEAFYAGTAFLIILLIGWLLTRFVGV
                     FVHGLTYVPILRQVDWIAGGILSLIMAYVTIFLILQLLAFVPLDVVQNQFGEHSFARF
                     IVERTPFLTNKMYELWVTNILN"
     gene            60320..62680
                     /locus_tag="LLC22_000456"
     CDS             60320..62680
                     /locus_tag="LLC22_000456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endonuclease MutS2"
                     /protein_id="HBK5433760.1"
                     /translation="MNNRILETLEFEKVKQMVRQFVVTAQGKEELAELVPVSEKQTIT
                     NWLQETEDGLKVQRLRGGIPIPKLENIRPHMKRIEIGADLNGVELAQVSRVLSTTSEL
                     NRFIDDLSDSEIEFARLYMWADQLVTIPVLSRRLKEAIDEDGRVTDDASPELKSIRQN
                     IRRSEQAVREQLDGIVRGKNAKYLSDAIITMRNDRYVIPVKQEYRGVFGGVVHDQSAS
                     GQTLFIEPKQVVDLNNRLRQYQIAERNEIQRILSELSAELVPHRQEIIHNAYVIGKMD
                     LMNAKARFGKEVKAIVPGISEDNHVVLKQARHPLIDQEKVVSNDITIGKDYQAIVITG
                     PNTGGKTITLKTLGLLQLMGQAGLPIPAGEESQIGIFEEVFADIGDEQSIEQSLSTFS
                     SHMTNTVDILSKVNEKSLVLFDELGAGTDPQEGAALAIAILDDLGKKSAYVMATTHYP
                     ELKVYGYNRANTINASMEFDVDTLSPTYRLLIGVPGRSNAFEISSRLGLDTEVIDEAK
                     QLMNDESQDLNEMITDLENRRKMAETEYLEMRHFVSEAQELHDDLKEAYSYFFEEREK
                     EMEKAKKKANEVVSEAEEKAEKIIADIRKMQQQIGQGNVKEHQLIDAKTQLANLHQEE
                     TLKKNKVLKKAKEQKTLKPGDEVLVTTYGQRGTLLRKNGNQWQVEIGILKMNVSEDEL
                     TPVAPQKEPTQRVIHAVRSESSSHVPNQLDLRGKRYEEALSEVDQYLDSAILAGYPQV
                     TIVHGKGTGALRKGITDYLKNHRSVKSFEFAPANQGGNGATIVKFK"
     gene            62767..63081
                     /gene="trxA"
                     /locus_tag="LLC22_000457"
     CDS             62767..63081
                     /gene="trxA"
                     /locus_tag="LLC22_000457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin"
                     /protein_id="HBK5433761.1"
                     /translation="MSQVITDKTFNEETDKGLVLIDFWATWCGPCRMQAPILDQLEQE
                     YDEEEFRIAKMDVDENPETPQQFGIMSIPTLMLKKDGQVVEKAVGVHSKEQLRQMIDQ
                     YL"
     gene            63263..65041
                     /gene="uvrC"
                     /locus_tag="LLC22_000458"
     CDS             63263..65041
                     /gene="uvrC"
                     /locus_tag="LLC22_000458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346080.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrC"
                     /protein_id="HBK5433762.1"
                     /translation="MNERIKNKLALLPDQPGCYLMKDKNGTIIYVGKAKILKNRVRSY
                     FTGSHNTKTERLVSEIEDFEYIVTESNIEALLLEINLIKKNDPKYNIMLKDDKTYPFL
                     KITNEKYPRLVITRKVLKDKALYFGPYPDVGAANETKKILDRLFPLRKCKPSQTKEPC
                     LYYHLGQCLCPYYFDVDPKVYTKIVDEVKKFLNGGHEKIESEIHQKMEKAAENMEFEK
                     AAEYRDQIRAIETIMTRQKMTNTDLLDRDVFGYAIDKGWMCVQVFFVRQGKLIERDVS
                     MFPFYNEAEEDFLTYLGQFYQENEHFIPKEVLIPDTIDKPSVEALLATKVLQPKRGEK
                     KKLVELANKNASVALNERFDLIARKQERTIGAVERLGNAMNIPTPIRIESFDNSNIMG
                     TNPVAAMVVFIDGKPARKEYRKYKIKTVNGPDDYASMREVIYRRYSRVIREGLPLPDL
                     ILIDGGKGQVDVAKDVLENQLGIDIPIAGMAKNDKHKTNELLFGIDLAVVPLERNSPE
                     FFLLQRIQDEVHRFAITFHRQLRSKNSFASRLDEIEGLGPKRKKMLLKEFKSLKNITA
                     ATTEELQEIGLPKNVAQNVFDKLHQE"
     gene            65186..66085
                     /locus_tag="LLC22_000459"
     CDS             65186..66085
                     /locus_tag="LLC22_000459"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5433763.1"
                     /translation="MLEVKDLVKTFGNYTAVDHVSFQIPDGKIMGLIGQNGAGKTTTF
                     RLILDFLTQDQGEVLWNGHHLGEKDYDVIGYLPEERGLYPKVTIQDQLLYFAELRGKS
                     RKEIEPKIDFWMEKFQVKGKKTDKVKSLSKGNQQKVQLIATLIHEPKLIILDEPFSGL
                     DPVNAELLKDGILELKKHGSCVIFSSHNMDNVEKICDHLIMLRNGKMVLNGKVHEIRE
                     SFGRTKLFLESGLSQQEVEEIEGVKKVILHEDNTLEITLEDPEAGKEIFTRATQFGYI
                     PMFNQQPPTLEEIFKLKAGEIDA"
     gene            66078..67340
                     /locus_tag="LLC22_000460"
     CDS             66078..67340
                     /locus_tag="LLC22_000460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5433764.1"
                     /translation="MRKFWIITKDVYLKNVKSISFLIMILVPFIMLGIIYVAGNFAQQ
                     NSDVNKIGVLADNEQISQQMSQVKTDDFEFKAVDSEEKAQKELSEEKIDAYLVVSTEN
                     DKINGMLYSENSLGQSTQLLIQQQLTGLQSMLRASQLGISPEEVASLSQQASLTRQKV
                     NFDSKGKMTVGEDNSTVQYVVSYVATIVLFIIILTYAQIIAQEIASEKGTRIMEVILS
                     STTAQKHFYGKLTGVLLVALTQMALYGIIFGIGYSQFKDMEMVKNILDGISLDNLIGP
                     FLWCSLLFMIFGILIFSVLAALCGSLVNKAEDTAKAILPVTYLSLGGYMLGLILGASD
                     PNNIVIRITSYIPFLSSYIMPVRLANETVGMGGALISLLVLVAVTFLLMILSANMYKS
                     NVLVYSEGGLWSSLKQSISIMRNERKKA"
     gene            67501..69399
                     /locus_tag="LLC22_000461"
     CDS             67501..69399
                     /locus_tag="LLC22_000461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphatase class III"
                     /protein_id="HBK5433765.1"
                     /translation="MDRYLDLLSEKFPTTEDVITEIINLEAILQLPKGTELFLSDIHG
                     EFPAFDHILRIGSGNLKEKIKDLFSEQMTETEISQFTIFTAYPEYVLTTDWYKKQDKS
                     QLIHRLIDLLRFTTVKYTRSKVRKGLPKEYSYIIEELLYIDDRINGKKDYVKKIIEQL
                     VLMKEEEKFLTKLAQTIQKSVIDHLHIVGDIFDRGTQAAKVMDRIMDFSSVDIQWGNH
                     DILWIGAYCGSEACLLTLLRIAARYNYLFELEKEYGLNLRPLFSFAHQTYQKNPVFTP
                     KNRKDLSEREQEELEKIHQALSILQFKSEHQLLNRRPEFKMDDRKLLEKINYEESTIV
                     LEGQLYELKGTCFQTIQPDDPKKFLEEEQKVIDSLMYSFQHSLRMQKHMTFLIEKGGM
                     YLTNNQHVLFHGCIPVDEKGQLLAFELDQSYRGKELLGFFEKQITESAKDLTANEDLA
                     TDLIWYAWSGPFSPLFGKSKMATFERYFLTEPHTHVEKSNPYYHLRDEEWFSEKILAE
                     FDAKEEGSAIINGHTPVKVKKGESPIKANGKAFVIDGGLSKAYQKTTGIAGYSLLCNS
                     YGFQIVTHYPFLPIEQQFAKKSDQTNVKKVIEQQLPRKLNRNTTKGMELQQQITQLQR
                     LLDYRKDD"
     gene            complement(69698..70417)
                     /locus_tag="LLC22_000462"
     CDS             complement(69698..70417)
                     /locus_tag="LLC22_000462"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma-glutamyl-gamma-aminobutyrate hydrolase
                     family protein"
                     /protein_id="HBK5433766.1"
                     /translation="MKPIIGIAGNQLIRATDTFQGNQVSYTPQGFVDAVLDAQGLPLI
                     LPVMSPDSAPQLIEKIDKLILAGGQDVSPQLYMEDPHPKLTETNIQRDQFEQALILEA
                     LKQRKPIFAVCRGLQLLNVVLEGTLYQDLSLYPKWSVKHEQQPTAPQFATHEVKIVSD
                     SLLSDLLPDSYFVNSYHHQAVKDLSPLLKAIAFSNDGLIEAVQSKDNMHKILGVQWHP
                     ELSHRVDSSEQRLFDFFVNEF"
     gene            70754..71086
                     /locus_tag="LLC22_000463"
     CDS             70754..71086
                     /locus_tag="LLC22_000463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433767.1"
                     /translation="MKQVLEALEQIRKAEEENEKRARTLRQQLKTYAEEKEQELEIIQ
                     TNSRQQLKQLVEEKEQFEKQELEKEKMKLKAEADKVQATLKDQYQKHQSQAIGAIIER
                     VKETYGRH"
     gene            71073..73076
                     /locus_tag="LLC22_000464"
     CDS             71073..73076
                     /locus_tag="LLC22_000464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit I"
                     /protein_id="HBK5433768.1"
                     /translation="MAVTKMEKVTLISDKRNQERILQAVQGIQNVEIRDLYQNRTNNQ
                     WVEKYFPDTTIIDKEAKLSALGNRLKDIQEAIQFIQHHGDSRQKKLHLKRQELSLQDL
                     EANYSEENFMNKLEEVLDLKEKWEQLTEKRDRLEEEEEWLLHWQQLDIAPSMYASKTT
                     IFEMGTVSAANFESFKEELSKLDDVYMEEIDYTPKQVYLSYVALKKSVAAIEEIAGKY
                     GFNKETYPYEQNPKEKLQETKQQLSIVHEQQKKITTALGQCSGYIQEFEWVEEVTLAV
                     AEREKVKERFIHATYLIVLQGWVDAEEKQNLMHVLNETVSEEDIYVSFETPNSEEIQQ
                     EVPTKLKNHPLIEPFELLTEMYSLPKYEEVDPTPWMTPFYLVFFGMMVADVGYGLLML
                     IGTILAQKLFVLPRGMKRFVKFFEILSVPSIIWGLIYSSFFGQALPKELFGIRLPFPI
                     LSTTDDVNTILILSVIFGLIQILVGLFVAAKENIRRKDYLSAVSDGFAWQGILIGIVI
                     ALIGVMLIKNTAFVYLGAGLSIIAALCILIVPIIQSPSKVKGAAKGAYNLYGLTGYIG
                     DLVSYTRLMALGISGGSIGAAFNMLVAFMPPAARFSVGILLIIALHALNMFLTLLSAY
                     VHGARLQYVEFFGKFYTGGGRAFDPLKTAEKYVNINHKKKNNK"
     gene            73095..73565
                     /locus_tag="LLC22_000465"
     CDS             73095..73565
                     /locus_tag="LLC22_000465"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit K"
                     /protein_id="HBK5433769.1"
                     /translation="MMDYLISQNGGMVFAVLAMATATIFSGIGSAKGVGMTGEAAAAL
                     TTSQPEKFGQALILQLLPGTQGLYGFVIAFLIFINLGNDMSVVQGLNFLGASLPIAFT
                     GLFSGIAQGKVAAAGIQILAKKPEHATKGIIFAAMVETYAILGFVISFLLVLNA"
     gene            73586..74170
                     /locus_tag="LLC22_000466"
     CDS             73586..74170
                     /locus_tag="LLC22_000466"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase V"
                     /protein_id="HBK5433770.1"
                     /translation="MNAIEKIISQMNEAAEQERAALEQEERMKIDQNFEQKRTQIETE
                     HQKQKEKQIELLEKKYRQLRNRQQVEVRQENLNAKQEFLRRLFADAIAEMENWDESEQ
                     IQFIKNSLYSLPLTGKVTFIAGEKSAAYLSQTLLDEWNNELPFMMVLSDETVADQAGF
                     LINDQGVQYNFLFSSLVQDIQGTMSFEIANQLFE"
     gene            74185..75171
                     /locus_tag="LLC22_000467"
     CDS             74185..75171
                     /locus_tag="LLC22_000467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATPase subunit"
                     /protein_id="HBK5433771.1"
                     /translation="MEYHELNPLIRGRELELLSNETFERMIQTNSVEALGEILKSTIY
                     SPYIYDGYEYDFEQNLLKEQSRLFRWLKESAPEPEIVWIYTMRYTFHNLKVLTKAEMT
                     NQNLDHLYIDDGFYSLETLKDAIHTQVSNELPESIMDSIREVRDYFEESTILQGIDVI
                     YDRQFLTEQRRLADKLGYQELLTEVIAFIDLTNITTMARGILQKRTYGFMTTVLSSSG
                     SIEKEVFLNFVDKDMEDYTNFLLETDYADFLRPVIREGNLDLVKLEQLKDDYLSSLYQ
                     EAQTQAFGPLPLLAFLNAKEVESKNLRLLVIGKRSHFEPETIRKRVRQVYDA"
     gene            75161..75472
                     /locus_tag="LLC22_000468"
     CDS             75161..75472
                     /locus_tag="LLC22_000468"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit F"
                     /protein_id="HBK5433772.1"
                     /translation="MTHKIGVVGDKDSVLPFKLFGFDVRYGTTKQTVRQAIEEMAKNE
                     YGVIYVTEQCAALSPETIERYKEQMIPAIVLIPNHQGSLGIGLEEIQKNVEKAVGQNI
                     L"
     gene            75494..77275
                     /locus_tag="LLC22_000469"
     CDS             75494..77275
                     /locus_tag="LLC22_000469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit A"
                     /protein_id="HBK5433773.1"
                     /translation="MQIGKIIKVSGPLVMAENMSDASIQDMCLVGDLGVIGEIIEMRG
                     DVASIQVYEETSGIGPGEPVRSTGEALSVELGPGIISQMFDGIQRPLDTFMEITQSNF
                     LGRGVQLPALDHEKKWWFEPTVEAGETVSAGDVIGIVEETKVIKHKIMVPNGIKGTIK
                     TIEKGSFTIDETVCVIETENGDKNLTMLQKWPVRRSRPIKEKLNPDAPMITGQRVIDT
                     FFPVTKGGAAAVPGPFGAGKTVVQHQIAKWADVDMVVYVGCGERGNEMTDVLNEFPEL
                     IDPNTGESLMERTVLIANTSNMPVAAREASIYTGITIAEYFRDMGYDVAIMADSTSRW
                     AEALREMSGRLEEMPGDEGYPAYLGSRLAEYYERSGRVIALGSEGREGSITAISAVSP
                     SGGDISEPVTQNTLRVVKVFWGLDSSLAQKRHFPSIDWIQSYSLYSTEVGKYMDHILQ
                     ADWASMVTEGMRILQEEQQLNEIVRLVGIDSLSDNDRLTLEVAKSIREDYLQQNAFDD
                     VDTFTSREKQFKMLKMILTFGEEGRRALSLGAYLSEIMDGTVSIRERIGRSKYIPETE
                     LEKLDQIIGEIKQTMQTIVSEGGMSND"
     gene            77268..78644
                     /locus_tag="LLC22_000470"
     CDS             77268..78644
                     /locus_tag="LLC22_000470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit B"
                     /protein_id="HBK5433774.1"
                     /translation="MIKEYRTIGEVVGPLMAVEKVAGVKYEELIEVRMQNGEIRRGQV
                     LEVQEDKAMVQIFEGTSGINLRDSSVRFLGHPLELGVSEDMIGRVFDGLGRPKDNGPE
                     ILPEKHLDINGEVINPVARDYPDEFIQTGISAIDHLNTLVRGQKLPVFSGSGLPHKEL
                     AAQIARQATVLDSSDDFAVVFAAIGITFEEAEFFMEDFRQTGAIDRSVMFMNLANDPA
                     IERIATPRMALTAAEYLAYEKGMHVLVIMTDMTNYAEALREISAARREVPGRRGYPGY
                     LYTNLATLFERAGRIRGLKGSVTQIPILTMPEDDKTHPIPDLTGYITEGQIILTRELY
                     KSGIQPPIDVLPSLSRLKDKGTGPGKTREDHAATMNQLFAAYAQGKQAKELAVVLGES
                     ALSDVDKIYAKFAERFEKEYVNQGFYTNRSITETLDLGWELLSMLPRTELKRIKDDML
                     DKYLPEGK"
     gene            78651..79286
                     /locus_tag="LLC22_000471"
     CDS             78651..79286
                     /locus_tag="LLC22_000471"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="V-type ATP synthase subunit D"
                     /protein_id="HBK5433775.1"
                     /translation="MARLNVNPTRMELTRLKKQLTTATRGHKLLKDKQDELMRQFILL
                     IRKNNQLRQEMEESMTEAMSDFVLANASITEPFIEELFVLPAENVDLSIVDKNIMSVK
                     VPVMNFEYDEQLTDTPLEYGYLNSSAELDRSIDRFTTLLPKLLELTEIEKTCQLMASE
                     IEKTRRRVNALEYMTIPQLEETIYYIRMKLEENERAEVTRLIKVKNMGTTD"
     gene            79316..80671
                     /locus_tag="LLC22_000472"
     CDS             79316..80671
                     /locus_tag="LLC22_000472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBK5433776.1"
                     /translation="MIKQSKQIKKRLPAVQLLALGFFLLILVGGGLLTLPFFSNSGHG
                     TNFIDALFTATSAVCVTGLTTLNTAEHWNSAGQFLIMLLIEIGGLGFMMVPILCFALI
                     KKKVSLSTRIILKEALNLEEVSGVMKLMLYILKFAFVIQLIGTVALSFVFVPEFGWLK
                     GIWYSLFHAISSFCNAGFDLLGDSLANHQQNVYLIMVVSALIISGGLGFIVWRDLLEY
                     HQKKKITIHSKIALTVTGTLLLGGFVVFFFTERNGETLVEGNMFQRLANTFFMSVTPR
                     TAGYYSVDYLHMSHAGLILTMFLMYIGGTSGSTAGGLKTTTLGVLLIQMRSMLKGRTR
                     AEAFGRTIRQGAVLRALTLFFVTLTLCVVAIMILSVTETIPKTSGIEYIAFEVFSAFG
                     TVGLTMGLTPDLTAIGKLIIIALMYIGRVGVLTVVFSLMTKAQRTQSKYKYPEESVMI
                     G"
     gene            complement(80863..82257)
                     /locus_tag="LLC22_000473"
     CDS             complement(80863..82257)
                     /locus_tag="LLC22_000473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK5433777.1"
                     /translation="MPINSYDNYPLTWRPDKQKLKRPYYRSLIQQLEQDILKNKLQKN
                     TQLPSQRELADYLDLNFTTVGKAYKYGIEKGLLYTNIGSGTFISPNVFESITISTNEV
                     TEHIIDFGLVSSFEECNKFVVPFIQSTSNNPNLVGLLNYQDPKGTNFQLTTAANWLKT
                     QGVIPSLESLSIVSGVQNGLAITLSALFSPGDRIATDRYTYANFIELAQLYHLEIVPI
                     DFDEQGMRPDILIQECRKKKIHGVFLMPSCNNPIGFQISHKRREQLAEVIEKEGLWVI
                     EDDIHSFLTTYYQHTIIPPFQKLLPNQTIYLAGMTKFICSGLRVAYLVVPVHVQNKIE
                     QAIFNINVKTSGLDVEVITQILHSNEANRILETKLSLTKRANQLFDSLFKVEKPTNRV
                     PYYRILPVDPEIDPKIIENDFLANGIRLYHSRRFTTRAQPDAFVRISLSSNNLEILAS
                     GLSIVKEKIKKYEL"
     gene            82349..83320
                     /locus_tag="LLC22_000474"
     CDS             82349..83320
                     /locus_tag="LLC22_000474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine cyclodeaminase family protein"
                     /protein_id="HBK5433778.1"
                     /translation="MKIINFEEVVASFSFEEAIQVMKKCFFDYESGKISQNPRLVEIL
                     PDGKDKNMFAMMPAYLGENRYFGTKVITAFPDNHQYHLPSHLGEIFLFDAQNGLPKAL
                     INANAVTWIRTAAVSALATDYLANPHAETLALIGAGQQALSHLTAISTIRPITTVFVY
                     DILEERRNTFIAKAKKQYPKITFINAISVEDAVRPAEIICTLTSSKEAFLQKEWVRED
                     AHINAVGTFTPDTREISTSLMETSQIYVDDYSATLTESGDLLIAMAEGDLEESCIVGT
                     LGELVSEKKTFYKGESRPTIFDAVGLAIEDLCCAEYIYNKLEKGALK"
     gene            83317..84098
                     /locus_tag="LLC22_000475"
                     /pseudo
     CDS             83317..84098
                     /locus_tag="LLC22_000475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295114.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PhzF family phenazine biosynthesis protein"
     gene            complement(84267..84638)
                     /locus_tag="LLC22_000476"
     CDS             complement(84267..84638)
                     /locus_tag="LLC22_000476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5433779.1"
                     /translation="MKMAHTCVRVKDLEASIEFYQKAFGFEESRRRDFPENKFTLVYL
                     TLPGDDYELELTYNYDHGAYDLGDGYGHIAIAADDLEKLHEQHKAAGLEITDLKGLPG
                     TTPSYYFVIDPDGYKIEVIRG"
     gene            84772..85215
                     /locus_tag="LLC22_000477"
     CDS             84772..85215
                     /locus_tag="LLC22_000477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325070.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX domain-containing protein"
                     /protein_id="HBK5433780.1"
                     /translation="MDKPIFGEKKQSANYQTRYAAYIVIERDKRIAVIEAPNGAFFLP
                     GGEIEGEETKEEAIVRELIEEMGIVAEISSYLGEADEYFYSNYRATYYYNPGYFFVAD
                     SWKRIGEPTEKTNKIWWVSPQEALVKLKRGSHRWAVERWIEKNKN"
     gene            complement(85258..86067)
                     /gene="yidA"
                     /locus_tag="LLC22_000478"
     CDS             complement(85258..86067)
                     /gene="yidA"
                     /locus_tag="LLC22_000478"
                     /EC_number="3.1.3.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-phosphatase"
                     /protein_id="HBK5433781.1"
                     /translation="MSIKLVAIDIDGTLLNEKREVTKEVKEAIAAAVAKGVSIVLCTG
                     RPLPGVQEQLNELNLFQDNDYVITYNGALVQQTKSGKIIARHGLTHEDFLEIEVMARR
                     VGSHLHSIDDKAIYTPNRDISAYTIHEASLVKMPLKYRTPEEMTPDMNIVKMMMIDEP
                     EILDAAIARLPQTFRDKYTTVKSAPYYFEVLNKEASKGAAVANLAQHLGIDQDEIMAI
                     GDNENDLSMIEYAGLGVAMGNAVSLVKEAANVITSSNDEHGVAEAIKKYVL"
     gene            complement(86086..87453)
                     /locus_tag="LLC22_000479"
     CDS             complement(86086..87453)
                     /locus_tag="LLC22_000479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5433782.1"
                     /translation="MTTPYKYQMLPMEKVFRDPVHNYIHVQHKVILDLINSKEVQRLR
                     RIKQLGTSSFTFHGAEHSRFTHSLGVYEISRRICDIFSRNFSKEKIGNGGWDDQERLV
                     TLCAALLHDVGHGPYSHTFEHIFHTNHEAITVEIITSPETEVYQILNRVEEGFPEKVA
                     SVIQKTYPNPQVVQMISSQIDADRMDYLLRDAYFTGTEYGTFDLTRILRVIRPYEGGI
                     AFSMSGMHAVEDYIVSRYQMYVQVYFHPVSRGMEVILEHLLHRAHELYQEDASSFELH
                     SQLLLPFLDGSFTLEEYLKLDDGVLGTYFTQWSESADPILNDLAKRFLNRKPLKSATF
                     SGNRDSKLVQELTLLVEKVGYNPVYYTAVNSSYDLPYDFYRPEQGRHRTQIEILRNDG
                     TLIELSQVSQLVAALAGQEQGDERFFFPKEMVDPSLRDHYDLFDETYQEFASHIRNGA
                     LIEIN"
     gene            complement(87437..88267)
                     /locus_tag="LLC22_000480"
     CDS             complement(87437..88267)
                     /locus_tag="LLC22_000480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase family protein"
                     /protein_id="HBK5433783.1"
                     /translation="MNPAIRLDQHIYQKNDFSPFALTDILTEYSKEHQQIFLHFWQYD
                     CTVILGMKDVRTPFLSDGIQTLKDAGYAPVIRNSGGLGIVSDEGILNISLIFPQSDTK
                     KITIDDAYEQMLLLTKYAFPKAPIQAFEITHSYCPGTYDLSIHGKKFAGIAQRRIKNG
                     ISVMMYLSVNGNQEKRGQVMKRFYQSALKEDFGTNGYPAVDPATMATLEELLDQPLFV
                     KEVKEAFAKAFEKLYSASDLQDSTDWLKKEIQLEQWNNQIQRMEQRNNIKELHYDNPL
                     "
     gene            88430..88867
                     /locus_tag="LLC22_000481"
     CDS             88430..88867
                     /locus_tag="LLC22_000481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292826.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1934 domain-containing protein"
                     /protein_id="HBK5433784.1"
                     /translation="MELSQGTPISIKLRTKVKQQGEVQDFYFDLKGQMVTIGDTLYIR
                     YKEIQEETGDEIPVTIKLVPDGHVQLIRAGEMRMRLKFGYKERLETSYRTPYGMIQIA
                     TFTKELHVSLKDRPTAGKVRIDYDLFMGPEKIGEYYLTLDFTA"
     gene            88943..89563
                     /locus_tag="LLC22_000482"
     CDS             88943..89563
                     /locus_tag="LLC22_000482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit delta"
                     /protein_id="HBK5433785.1"
                     /translation="MEISVFEGANKSELSMIEVAHAILEQRGDVMDFSDLANQIQNYL
                     EKSDSEIRDSLAQFYTDLNIDGSFISLGDNRWGLRSWYAIDSIDEEVNHGMDEEDEDT
                     PRRRKRKKVNAFINDDEDAIDYNDDDPEDTDLTEEDDDDLFDDDDDEDEEIAAYNSDL
                     QEIGADDPTDDEEDLPGNIEEDLSIIDEDDDDEDYEEEEFSDSEKE"
     gene            89752..90258
                     /locus_tag="LLC22_000483"
     CDS             89752..90258
                     /locus_tag="LLC22_000483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor"
                     /protein_id="HBK5433786.1"
                     /translation="MIFTGYKKKRQIEKYRHLLNGLIETDYQKMFRITMNYVHDKEEA
                     LDVMQDSFHKALNYFEKEKEIEHFSAWFYRILIRTALDSWRRQKRTPVDLFEIQDIPQ
                     QLPLETSVAELHMILDKIDSPEKEILILYFFEGFRLKEIATILDMNENTVKTKMYRSL
                     NALRQILE"
     gene            90275..91174
                     /locus_tag="LLC22_000484"
     CDS             90275..91174
                     /locus_tag="LLC22_000484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3298 domain-containing protein"
                     /protein_id="HBK5433787.1"
                     /translation="MYSQKENLKKLKKTYKEQAIPKGLKEEIRQRFIIEEQSFIKARR
                     RKRRLQGFGVSLAIVMITTSSLLFNSQVRSFAEDLPILGSVIELILGERFTDRSEKID
                     IQVPKINTQNEKENKTIHGLNQKYFREGQADFEKAEKEYGNFETDHYQVLGDYQKIVD
                     DNRFLVIERQITQTAADSHVEKRYDTIDKKNSVQLSLPLLFKDDTYLSVLTKEVKRQM
                     AEQVKEDPSKYYWTEQDIQEGTIEKPTLVTPTRSFYLNKEHQLVLTFSQYEIAPGYMG
                     TPEFVIPKSVTKTILASEDYLDH"
     gene            91261..92146
                     /locus_tag="LLC22_000485"
                     /pseudo
     CDS             91261..92146
                     /locus_tag="LLC22_000485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295129.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide deacetylase family protein"
BASE COUNT        30491 a        15647 c        18973 g        27113 t
ORIGIN      
        1 ttaaataaat aggaacaaaa aaattaaatt atttaataca cacattaggg atcattcatt
       61 gaaggattag aagacaacga ggatggcgaa aaatatgatt acaatagaaa agtcgttcta
      121 aaccaatcag ttcctagtat cacacaacgc aagccagtcg atttggtgag attagaggag
      181 tgaaagcaaa ctttattata taagaaaaaa tattcgaaag ggatgctagt ttaggtacta
      241 gtgctgatag attaatatga tgcctcgtaa tattaggcgt agttactcta gagacatcac
      301 tatggactat gatttgtctc agagtcacaa catgtttttt tatgaaaaga aacagctaaa
      361 ataattaaat tgcgcaatgt ttaaactttc ttaaactata acctaataaa tgtgaagaaa
      421 taatgcacaa tttcttcaca tttatcttct attctatata cataccaacc aacaacccta
      481 tatacttttt catttttact cctcaagtaa aaataactcc tagaccgcgg ctacccaccg
      541 cggtcgtttt tttattcttc aatcaaaatc gctttgatac ccaaacctgc caagattcgg
      601 gcagaagtat aagtattcaa tcctcttctg aaagtaatgt aaactttttt atcttttggg
      661 atttcattga ttcgatctcg taactcattc attggaatat tttttgttgc cgagatactg
      721 ccagaaggtg ctttattagg ttcacgtata tctaaaaaga acgcttcttt caaatcgttt
      781 tcgggtatat cacttgcttt gatcgtttct acgatattcg tcatttgatt gattgcgaca
      841 taaccagcta tattcaacgg gtcacgggta gtagaatacg gtggagagta aggcaactcc
      901 aaatcaggca aatcaaagac tgtcaagttt ccggtgattg ctacagaaag ttctcccatc
      961 cgtttatcga cacctttttc tccaaatgct tgtccaccta aaatacgacc gctatctgca
     1021 tcaaaaatca gctttagatt taatcttgta gcttctggat agaaataggc atggtcaaag
     1081 ggagtgataa aaacagtttt ataatttgtt atgcctgatg cttttaattc atgttctgtc
     1141 attcccgcat aacttgctgt atgatcaaag atttttgcga cacctgcacc aatatatccg
     1201 cgatagcgca taggcgtacc atttaaaata tctgccagca tatgtccttg acgattggcc
     1261 gcactggaaa gcatactttg gatcggctga ccagtcacta cactagtcgt ttcgataata
     1321 tcgccaatcg catagatgtc cggcagattg gtttgtaact ggtcatcaac aatgatctga
     1381 cctgtatctg ataattgtat gccggttgct ttcaccactt cattcttcgg agaaacacca
     1441 acagcaaaaa ttagcatatc agcagaaagg acggagccat ctgataatac tatttctcga
     1501 cctttatcac ggatctcagt aactcttgtt tctaaatgaa cggctaatcc ttctttcagc
     1561 aatttgtcat aaactaaatt agcaatttct ggatcataag ggaaagcgac ttgtggcaat
     1621 tgatcgatta aagtcacgtc taagccgcga tgcttgaaat tctcagctaa ttccagaccc
     1681 ataacacctg caccaagaat gacgacatgt tgtggatttt tttcttcaag gaacgatttg
     1741 attcgatccg catccgtcac actacggagg acaaagccgt tttctgcttc aaaaactccg
     1801 ggaatatccg gataatctgg tctagcacca gaagagatga tcaacttatc gtaatctgtt
     1861 tttatttctt catttgtgga taggtcttta actgttaatc gcttagtaga aggatcgatt
     1921 gctgttactt cgtgtttagt aaagacatcg atgttgtttt ttgttttcaa tatttctggt
     1981 gtacgttcga tcagcgagtc acggtcagtg atcacacctc ctaaataata aggcaaagca
     2041 caacttgcat aagaaatatt ttctccgcgt tcatagataa tgatttcgtg cgcttcattc
     2101 aatcgacgga aacgagtggc aaatgaagga ccgccagcta caccgccaat gacaacaact
     2161 ttcataaaaa catctccttt tctacgttga tcgtactatg ttatggtaaa aaacagcaaa
     2221 taattgtgcc ggaaaattat tgtttatttt gaatagacag aaaatataga gaaataattt
     2281 gtggataaaa cctaaaaatt tttttctatt ttaaggatag ataatacttt gaaggggata
     2341 accctgtata ttttttaaaa gctgaagaaa aatgatggat cgaatgaaat cctaatatat
     2401 ctgcaatttc tgtataggtt aattcatttt ctagcacgag acgttttgct ttttccattt
     2461 ttagttcttt aaaatagcta ataacacttt ttccattcac ttttctaaaa tgttttttta
     2521 agctggctgg actgataaaa aaaatttggg ctaattgttc aagcaaaaaa ttttctgaaa
     2581 gatgttcttc taaatatcgt atgattggat caactaattc atctgaataa agaatatgct
     2641 tttttttagg aatgactttc tcatttgaag gtattgtcaa taaagcaagt tcctgttgat
     2701 aatgccttgg taaggaagac aattgaattt tttgcagaca ataagtaact aataaggaaa
     2761 gcaaatgaat gctcatctgt tggcatagta tgaaaaaaga attgatttcc tgatcatagg
     2821 aaatagctgg cttactatgt tttagataat caattttgaa ctgttcattt ttcagaaaag
     2881 taatgataga tgttatttct tgatctatag aaaaagattg tcccgtaata tgtgctaata
     2941 attgctcatc aaaataaaac tggataatga taaaagtttg tgtttccttt tgagtagaaa
     3001 agatttggac ttcttgctgt ttatcaatga ataaaaggga aggattatct agttctatag
     3061 atttatgtgc aaattcagca tataaattag cgctttcatt tattagtagt cgaaaatagg
     3121 gagcagcaga taaatgaaga tgggtatcta tggaataggt tagtgttttt ttgacaagat
     3181 tggaggattg gttgtttgtt aacaaaagaa ccactttcct ttctcttttt atataaaaag
     3241 ctttctattt ataattaatg actattataa caaaaatgaa aagccaaaac gacaagtaaa
     3301 atattttttt atataaatat ttgtgttact aattccgtta atatacataa gtgaaagcgt
     3361 tttatataag aacttgaaaa gaaagaaggg atagacatga aaaaaagata caaattggtg
     3421 atagctttgc taaacattac cctattattc agcttaagtg catgtggaaa aactaacgaa
     3481 gaagtaacag caaacatcgc agatccaatg ataaaaaaag ccactacatt agaagtatat
     3541 gtcgcaaacg gcaaactgac aaactatgtt gaaaatgctg caaaaatcta taaccgcaaa
     3601 actggagcaa atattgactt aaaaattgtg aatgtagctt cgggaacagc aacagtacaa
     3661 atgatcaccc caaaattggt aacacacgaa gatatgccgg atattatctc catggcagac
     3721 acttcagcag caggtgtgct ggaaaaattt caagatgctt tttatagtgc tgatgaatat
     3781 ggattttatg acaaatatgg cgatcagttt tatgatcaaa aattgaatat tttgcgtcaa
     3841 caaacgagta atgaaacgat tattccttgg gctagtgatt ttaccccagc actttgttat
     3901 tatcaaccaa aaaaatttgc tgaaataggt gtagattttg aagaaatcag ttcttgggaa
     3961 gaatatatcc aggtggcaaa agcattaaaa gaaaaaactg gtagttttgg aattgccttg
     4021 ccagaatctg gggaccaaga attgtttatc aacatgctag cccagcagaa tcaatctttg
     4081 cttgatgaag aaggaaatat ccgtctgaat actaaagaag cgaaacatgc tgcaaagtta
     4141 atcaaagaaa tgatcgactc agatattgta catttctacg gtgcacaaga tgctgagaaa
     4201 gcatttcaag aatctgcaat gtttgttgct ggcggctggt atgctacgaa tatgtctttg
     4261 aattttcctg atgcatctga caaatggcgc atggctccac tgattccttt ttcaaaagaa
     4321 aatccaggaa aaggtgcagt atcaggagga tcaagttttt atgtccctaa agatgccaaa
     4381 aatccacaag tggcacaaca atttcttaca tttatgctga cagatgaaga atgcttagcc
     4441 aacgcactgg agctgggcgt ggctacatct aactcattgg cctatcaaac agaagcagct
     4501 gagaaaaagt ttgactacta aggaggacaa aaatactatg aactattgaa taaaatcaat
     4561 gaaaatacat caaatactgt tttaccagcc acttattcag atgctacgtc ttatttgact
     4621 accgctgcat ataactattg gcaaacaggt gattttgaaa attcatatct aaaagaagca
     4681 gaaaattttg ctcataagta cggcgtaaaa ttaactggtg attaaaaaat attaggagga
     4741 cttaacgatg atgcaatctt cgttaccaag caagacaata aagaacagca agaaaaaagc
     4801 aacagatacg tctcataaaa aaagtgctta tggattggtc acaccttttg ttattttctt
     4861 tattgtgacg attttgattc ccatcattat ctcgtttgct tttagtttta tgaaaattgg
     4921 ctactcattt gaatttgttg gatttgacaa ttatctagct atcttccgag atccattgtt
     4981 tattaaatct tacacgaatg ttttgattat catggcagga tcaattccaa taacgatgct
     5041 attagctatt tactttgctg ttttattgaa ttcagcacag ttaaaaggaa aaggattttt
     5101 tagaactgtc tattatattc caaccattac atcaacggtg gctgtagctt ccgtattcat
     5161 gacttttttc aatccgactg ggttattcaa tggatttttg aatgcgctag gaattaacgg
     5221 tgtacagtgg ttaacaaatc ctttttggat acgaatatca atgatcatca cgatgatttg
     5281 gcttagtgta ggatataaca ctattttatt tttagctggt cttcaaggga tttctaaaga
     5341 gatatacgaa agtgctgaaa tagatggagc atcgaaattt cggcaattct ttttattaac
     5401 gatccccatg ctaaagccaa tcattttaat ggccacagtt ttagccacta tcaatggctt
     5461 gggtaatttc aatatcccaa atatattctt tgggacttcc aatggaccag aaaattcagc
     5521 tttggtcgta ggagtcaatt tatataaaac aagttttgaa atggttgatt ttggaaaagc
     5581 ctctgctatt gcctggacga tggtgtttgt atctgttata ttatcggcta ttcaatttaa
     5641 attcggaggt gataaaaatg actaaacaaa agatacaaag cagaattttt acgtacgtca
     5701 ttattgtgtt tggtgcctta atatttttga tgccatattt atatatgatt gtagcttcaa
     5761 cgcaaagtaa tcaagaaatt ttaagtggcg gaatcaattt caagtttggg gatatgctat
     5821 taaaaaactg gcaagccatc atggcgagat ataattatcc cttgattatt tggaattcga
     5881 ttgttattgc tgtaatcagt acagttttag ctacagccag ttctacaatg gcgggttatg
     5941 cattagcaaa gtatcgtttt atggggaata aactgttgtt caatacagtt atgctatcta
     6001 ggatggtgcc tttttttacc acattgattc ctttatttta cattatgagt cgtttaggat
     6061 tatcgaatac ttatgcaggt gtgatcatcc cttcgattgc cagtacaact tcagtgttta
     6121 tgatgcgaca atatagcagt caatttccta cagcactgat ggaggctgcc agaatcgatg
     6181 gtgccaatga gtgggtgatt tttacgaaaa tcgctgtacc gattttatca cctacgatta
     6241 ttactagtgg tttacttatc tttatgggaa gttggaatca atatctattt ccattagtca
     6301 tgctttcaga taaagataaa tatacggttc ccttaattat caaaaatatg acggtttcta
     6361 gtacaggtga gccaattaat tatggcgcaa ttatgctaat tttagcaact tcagtgatcc
     6421 caatggtctt gatttatgtg tgggcgcagt ctaaatttaa ggagaatgac attggagctg
     6481 caaataagta aaaaaaataa cgaatgttaa ccatctagtt cgttctagga gcaactccac
     6541 attcataaaa attaaaagaa tggcgggata tccatgaatg aacagacgaa ggaatggtca
     6601 agaaaaattt tgaatgtagc ttctgaaaag atagatgcgg aattagacag aatggggaat
     6661 aaaattccat atatttctta caacggaaaa tatacagacg taataaagga cagaggaatc
     6721 gactggtgga ccaatggttt ttggagtggt attttatggc agctctttca caagacaaaa
     6781 cgagaaaagt tcaaagaggc agcaatacaa caagaacaat tattagaatc tgccctgtac
     6841 catttttcag acgttcatca tgatgtaggt tttttattct taccatcggc tattgcacat
     6901 tatcaacagt ctcaaaacaa acatagtcga caactagggt tacatgcagc tacggtactt
     6961 gctggacgct ataatatttc agggaactat ttagtagcat ggaatgacca taaacctggt
     7021 tggatgatta ttgatagtat gatgaattta ccattactgt attgggcttc gagggaaact
     7081 ggtgatccga ggttctctaa aattgctcgg cagcatgcag atacaacagc taagtatcta
     7141 gtgaggaaag atggatcaac cgggcatatc gcagaatttg atgcagaatc agggaaatat
     7201 attcggttac ttggcgggca aggatacaat gagaattctt gttggagcag aggaaatgca
     7261 tgggctttat atggattcgc gttaagttat cgttacacaa aaaatccgta ctatctagct
     7321 atagcagaaa agatagcagt aaattttatt cagaaaatcg aaaaaactgg ttatattcct
     7381 ctcattgatt ttgctgtaaa agattcgaat attgatacca gtgctggagt atgcgctgca
     7441 tgcggtcttc tggaattagc aggatatgtt tcctctgtac gatcaaaaat gtatcatgaa
     7501 gctgctatca atatactcca aaagacagaa aagcactatg caaattggaa tatggatgaa
     7561 gatgggatca ttggaggcgg agcagaagca taccatagag aactgactta taatgtgcca
     7621 ctgatctatt ctgattattt ttttattgaa ggcttacttc gattagaaca gtcggaatta
     7681 gctatttggt agtaaaaaga ggagaaaata caatgaaaca tccagtacca ctattaagga
     7741 ccagacagga ttactttgac ttatttaaaa agataaatca accactccag ccgttttatc
     7801 gagcaagtgg cgcacaaatt gattatatac atcaaggggt aggatatgga aataaaattg
     7861 caggaatgga aggattctct cgggttttat ggggagcggg gcccgcaatt gaccaattag
     7921 atgaacgatg gttgaaatta attctatcag gaataaaagc tggaacagat ccttcccatc
     7981 ccgattattg gggagaaata catgaaagag accagcgtat ggtagaaatg cccgcaatgt
     8041 tattagcgtt atatcatcat gaacaattat tatggaaaaa attagataca ggagaaaaaa
     8101 gccagattat tcattggttc tcgcaaattt ttgaatatga atgtgcagat ggtaattggc
     8161 aattttttaa gataattgtc ggaacaatta tccaaaaatt tggttatcca gttaaagaat
     8221 cagcactgaa agaagcattt gataatatag aaaattgtta tcttcaaaat ggctggtatc
     8281 gagacagttc aagaggtcgc caagattatt ataatccttt tgcatttcat tattatggtt
     8341 tgatttatag cgtactagaa ccagaaaagc ccattagcca gatatataag aaccgagcta
     8401 ttgatttttc tagagactat attcattttt ttgcggaaga tggtgcaaat gtgccttttg
     8461 gtcgaagcat gatttatcgt tttgcagttt caagcttttg gtcagctatg ttgtgggccg
     8521 atcttttgcc ttttaaatta ggtgaaatca aggggttagt caatcggaat ataagatggt
     8581 ggatgcaaaa agaaatattt gatgaaaaag gtatcctgaa tattggttat acctaccctc
     8641 aattgacatt gactgaaccc tataatagta cgttatctcc attatggctg aataagattt
     8701 ttttattgtt ggcgctacct gaagaccatg agtattggac ggctaaagaa atgcctatgc
     8761 ctattcgtga aggaactaaa cttctttcag aagccaattt gctcatacaa catgataatg
     8821 gacatacatt ttttttgaat gcgggacaat tagggccaaa tttccataca ttgaccaatg
     8881 aaaaatattt aaaatttgct tattctagtc aatttggttt ttcgataccg cgagcgaatc
     8941 aattgaaagc agaaatggca atggattcaa tgctagggat tcagcgagcg gacacatata
     9001 tcacgaccag ttttaagaat gagagcatca aaacctatgg acagttcatc gttcgaaata
     9061 atgtacgaga cattgtatgt aagaaagagg tacttgcctc tacatgggaa cctactttac
     9121 aggcaaaaat cagaacttgg cttattcctt ttgaaggctg gcagattcgc gtacacaaag
     9181 tagaattaga tacagaatat gttctatatg agacagggtt tgctattgaa tgttctcctg
     9241 agaaagaagg aataatcata gaagaagaca aggaaaacta tagggtgagt gaagctggct
     9301 tttcaggtat tatctgttta agtgacgata ctattaaacg aaaatccaca gctattatgg
     9361 gtttgcccaa tacaaacttg atgacatggg aaaacacttt tattcctgga ttagagggta
     9421 catttggaaa aggaacccat tggctcggaa caggagtggt tgctcatcaa gatcgggatt
     9481 atagtttaga agtatggaac aatcgtccca aaattgattt tgatgggaca accgggctaa
     9541 ctatccaaaa taaaaacaat aaaaaaagac taaaattatg ctaaaggctg gtggggaaat
     9601 gcttgataaa gtgatgtttg aagagataat acatccagaa aaatggataa atgaatgtta
     9661 taaagaatta atggaaaaag aatggaataa tgagatcgag cgttgtcgca gacacacgga
     9721 gaggttaatc aaacgtatca gtaacagtca gtatcaattc ccaagcgagt gtcctataaa
     9781 aggacgttat ccattaagag acaatattgg ttggacagaa ggattttgga caggaattaa
     9841 ttggttgtta tttgagaaga cgggtgatcc tttatttcaa caaacagctg aaaaagcaga
     9901 tatagatttt atccacagga ttgactgtca aattatcact aatcatcacg atcttggttt
     9961 tttgtattct ttatcaaccg tagcagatta taaaataacg ggaaatcgaa aaatgaagga
    10021 agcttcaatt gatgctgcag aaacattact tcagcgtttt tgggagaagg caggagttat
    10081 acaagcttgg ggagatccta gtgatccttc acaacaaggt agaatgatca tggattgttg
    10141 catgaatctt ccattattgt attgggcgag tgaagaaact ggaaatcaaa aatataaaaa
    10201 agctgctcag gctcatattc aaaatgcagc agattattta gtaagagaag atggttcaac
    10261 ttatcataca ttttatatgg atgtcaaaga tggaaaacca agatatggaa gtacgcatca
    10321 aggttatagt gataattcct gttgggctag aggccaagca tgggggattt acggttttgc
    10381 attaagttat cgttatttga aagaacaaaa atattttgat ttaagcaaaa tattagccaa
    10441 ttattttatg aatcggttgc cagaagatac catttgttat tgggatttga tctttgatga
    10501 ttctagcaga gaagaaaaag atacatctag tatggtgatc atggtttgtg gattattaga
    10561 attaatagaa tcaggtctat tagacaaaac agaaaagaac ttataccagt ctgctgtttg
    10621 gaaaattatg cgacaattga aagaaagata tgctacaacg gaagaagaag atggcttttt
    10681 aacacagtct gtttataata agcccaaaaa taatggggta aatacacctt gtatttgggg
    10741 tgattactat tatttagaag ctttagtgag aatgactagt aattggtctt cttattggtg
    10801 aaaaaggtaa atatggaatt tttgtttgat aaaataaaaa aagaaaaacc aaaacagcat
    10861 gaatggtttc tgttttggtt ttttcgttaa ttttcatatt cttctaattc caagcttagt
    10921 tcttcccatt ccgtcaattt tgtttcttga tcttgtctag cagcttctaa atcttggttc
    10981 agctcattga gttttacgtg atcttccagg ttttctggcg cgaccatttc ttgttccaac
    11041 tgatcgatcc attcatcgat ccgcgccatt tcttcttcaa cctgagtaat ttttcgttga
    11101 aggctacgga taagcttttg ctgttctttg ctttggtaat aatcagattt gttcgtggga
    11161 gcaggagcag attctggctc atcttgtgcc aacaattcgg cgatttcttc ttcttcctgc
    11221 tttttctcta aataataatc atagtctcct agatagactt tgctgccatt ttcagagagt
    11281 tcgacgactt ttgtcgcgat ccgattgatg aaatatcggt catgggaaac aaaaagcagt
    11341 gtgccgtcat aatcgatcaa tgcattttct aatacttctt tgttgtcaat atctaaatgg
    11401 tttgttggtt catccaaaat caaaaaattt tctttgttca tcgctaactt ggctaaagca
    11461 acccgtgctt tttcaccgcc acttagcaga gggattggtt tttctacatc ttcgccagaa
    11521 aataagaaag cacctaaagc acttcggatc tctttttctg gagtggtagg atgctcatcc
    11581 cacaattctg ctaggatcgt cttgtttgta tgcagatcag cttgaccttg atcgtaatag
    11641 ccgatggtga catttgtccc tagcgtttct tttccacgga taaaagggat ctggtgaatg
    11701 attgatttca gcaacgtcga tttcccgata ccattcggac ctactagagc aatcgcttct
    11761 tgacgacgga tatctagatt gattggttca gataaggtga cattatcata tccgatagcg
    11821 gcatcttcga tttgcaagac tacatttcca gaaggctttt ctatactgaa tagaaagttt
    11881 gcttgttttt catccccttg aggacgatcc agccggtcca ttttttctaa tgtctttctg
    11941 cggctttgcg ctcgttttgt ggtagaggcg cgaacaaggt tccgagcaac gaagtcttct
    12001 aatttatgga tttctgtttg ctgcttttca taagccttcc attcacttgc taactgttct
    12061 gctttcaaat ctagatattt cgaatagtta cctttgtaat ggcgcatttt tcttctgctt
    12121 aattcataga cttcattgac tactttatct aaaaaataac ggtcatggga aacaatcaat
    12181 aatgcaccag tatagctttg cagataattc tcaagccagg aaagtgtctc gatatctaaa
    12241 tggttcgttg gttcatctag aatcaaaatg tcagggtgtt gcaaaagcat gcgagctaaa
    12301 gctaaacgtg tgcgctgtcc gcctgataaa gtatcgattt tctgatcata aaatgaagaa
    12361 tcgaatttaa acccatgcaa tacggaacga atttcatttt cataaccata gccgtttcga
    12421 tctgaaaaat cgtgttgcag ccggtcgtat tcttttaaat aagaactata agcaggtgtg
    12481 tctggcgtac cttcgctaat gaaaatctct agctcgcgca tccgctcttc catttgtcta
    12541 acttgttcaa aagctttcag catctcgttc caaactgttt cattggaatc aagtcctgtg
    12601 tcctgagcga ggtatccgag agtcgctgtt ttatttttag cgatctttcc ttcatcaggt
    12661 gcttcaattc cagcaatgat ctttaataaa gtcgattttc cagcgccatt tctgccaact
    12721 aaagcgacac gagcgcctgt actgatttct aaatgtatgt tttcaaataa gacttctgca
    12781 ccaaaatggc gagcaatctg attggcttgt aataatatca tggaatcctc ttttctactt
    12841 tgtgaattct cctcaaataa aaaactattt ttcaattagt agtctaccat aaattccatt
    12901 atactgcgag atttgcagaa atgataaata aatgaataaa gaataaaatt tcacaatatc
    12961 tgagcaatgg aattgatttt ttcctataaa tactgctatg atggagaaat caaagatgta
    13021 attagacaat acgtggaggt catttcgtga aagatcatat tattccaaag gcgacagcta
    13081 aaagactgcc tttgtattat cgctatttaa ggattttaaa taatgctgga aagaaaaaag
    13141 tgtcttcaac tgaattaagt gaagccgttc aagtagatag tgcaacgatc cgtcgagatt
    13201 tttcttattt tggcgaatta ggaaaacgtg ggtatggtta tgatgtagaa gatcttatgc
    13261 acttttttgc aaagacatta aacgacgatc aattgacaaa tgttgcgctg atcggtgtag
    13321 ggaacttggg aagtgcttta ctaaaataca aattccatca aagtaatagc atacgtatca
    13381 gttgtgcttt tgatgtgaat gaggaaatcg ttgggcgcat cgtagacggt atccccgttt
    13441 atccaatgga agatatgtca gaacaaatca agatccaaca aatcgaagta gcaattttaa
    13501 cgatacccgc tgaaagagca caagaagtag tcaatcagtt aacggaagca ggaatcaaag
    13561 gaatcttgaa ctttaccgct gctcgattga atgctccgtc agatgtattg atccaaaatg
    13621 ttgatttgac gaatgaattg caaaccttga tctatttctt gcattctgac gcaaatgcgc
    13681 attccgaaaa tacagcagaa taaaaataaa aagcgattga acaaatgaag gcaaaacttt
    13741 cacttgttca atcgcttttt tctgtttgga caacgattat tttgttcgga agatttcttc
    13801 ataagaaagg gaatcatctt ctgctgtcag ttcatctagt agataacgga tttttttaaa
    13861 gtcgatgaac cgtgcttgcc gaaagacttc ttttccttga tgaaaaatca ggacaactgg
    13921 cgcagtcagc acttcaaatt tactagctac ttctggtgtt tcaaatgcat ccaaatgaag
    13981 tgccggaata tcataatgtg tgagaagttc ctctagtcgt ggacgaacag cgtgacaaac
    14041 actgcaatta ggcatcgaaa gataaatgac ggcaacggat gactgttgca gtatgtcttg
    14101 aacttcagtc aagttagtgg tttgtttcat ttttattctc ccttttatga tagaagtgat
    14161 atgtatgaga ccttaattta atgggaataa cagaaaaagt caattgaagt gctttggtaa
    14221 aaaataagag ttgtgtaaaa atttacagag caacttgttt tttttgaata aaagcgtata
    14281 tttgcaaagc gaatgaacta gaaataaaaa ggaggaaact catgttttct tttattccaa
    14341 attcggtttt gcagatgagt acgattttct tatcgatcgt tattgaagca ttacctttcg
    14401 tattattagg ctgtcttatc tcaggcgcct tacaagtatt tttgacccca gaacgtgtga
    14461 agagatggct tcctgaaaat cgtatcttct ctatttttac tggttcgatc ttaggatttt
    14521 tctttccttc atgtgaatgc ggcatcgtac cgatcgttca tcaatttgtt aaaaaaggcg
    14581 taccagttca cacagcgttt gcttttatgc tgactgctcc gatcatcaat ccaatcgtga
    14641 ttttttccac ttttatcgca tttggcaatt cttggcagat ggcaagctgg cgggtgatag
    14701 gcagcttttt tgttgccctt gtgattggtg tctggcttgc ctattttcaa aaagacgctg
    14761 tattgaaaga aaaaatcacg tctaaagtag cagaaaatca ccatcatcat gtccatgaag
    14821 aagaacaaag tgagaagaat gaaccaaaaa atcagctgat ccatcaaact gggcatgtgt
    14881 tgacacattc aatcgacgaa ttttttgata caggtcgtta tttgatcatt ggcggattaa
    14941 tcgcagctgc gatgcagact tatttaccaa ctagaattat gctaacgctc ggctcaacaa
    15001 agattttagc cattatcatc atgctgttat tggcctttac gatgtctctt tgctcagaag
    15061 cagatgcgtt tataggatct tctttgttaa gtctgttcgg cacagcacct gtagctgcct
    15121 ttttggtctt tggcccaatg gtcgatatca aaaatctact gatgatgaaa cgatatttta
    15181 caggacgctt tattttatcg ctgatcggac tgattgccct tagcgttatt ggattcacat
    15241 tatttattta ggagggaaaa tatgctgcgg tttttgattt tatctgggta tttcgaattg
    15301 atgatgtact tgcaagtttc tggcaaactc gatcaatata tcaatgtcca ttatcgctac
    15361 ttagctattc tttcaatgat tttatctgct cttttggctt tagttcagct gtatttgtgg
    15421 gtcaaaaacg gaaaagcaga agaaaaggca cacgagcacg atcatgacca tgggttgtca
    15481 aaaccttatc aacgtggaat cgcttatgta ctgctagctt tgccagtaat cgtggggacg
    15541 ttgtttccaa cagttagtct cgacactacg atcgtagaag ccaaaggatt taatttccca
    15601 gtaagtaaag aatcagtagg ggatccggag atgcagacac aatacttaaa gccggatacc
    15661 agtatttatt tcaacaaatc agactactta gaccaaatga atgagttgaa agaaaagtat
    15721 ggggataagc aaactatcaa gatcacagat gaaaactatt tagaagttat ggagctaatt
    15781 tataattacc ctagcgaatt cattggcaaa aaaatcagct atgaaggatt tgtttaccaa
    15841 acaccgaacg atagcaatac agatatcttc ttgttccgat tcggcattat ccattgtgtg
    15901 gcagattcag gagtctttgg tttgttgacg catatgccgg aaggagtaac ggttaaaaat
    15961 gatgaatggt ataaaataga aggaaccatc caatcagact attatcaacc attcaagcgt
    16021 gaaatcccat ctgtagttgt tacaaacgct gagaaagtct ctgctccgaa aaatcagtat
    16081 gtgtatcgtt ctttttaaaa gaacaaaata aataaacata gctcagacag ctgacacgca
    16141 aggacgtcgg ttgtctggct ttttttgcat gatgtattca tttgtttgat atttatttta
    16201 gaagcagcat cctgaaagta tttgatatcg gtttcaaagg tgttggaaaa gattgtgaag
    16261 agaattacaa tttattccta acatgtatgt tgaaaagttg tatgaaatga ttttgatagt
    16321 aaaatatcga gtggaggtac tttttatggt aacgcgtata tttattttgg atgatagttt
    16381 ggtttttgaa aaaatgctag tagaaatttt ggaagaatcc agaattttat taagtccttg
    16441 gaaatttgag atcgttcagg gattgaacgt tatacaattt gttgaattca ttaaaaataa
    16501 tgaaatctat tcctcagata tttttttcct agacatcgat ttgaacgcct attatagcgg
    16561 tatcgaacta ggcgaaatgc ttagagaaaa gaatgaaaag tgtaaaattg tttatctaac
    16621 gtctcatccg aataaagcaa taactgttat taatcgaaag attacgccta gtggttattt
    16681 gataaaagaa ttcacttatg aaaaaaataa aaaaagcatc caaagttact tattgaaaga
    16741 aaaagaaaac tatcctgttc aacatgctac gaaaaaaagg tggacaactg tccgttatgg
    16801 taatagcgat cactatatcc attacgatga aatcctttat ctaatgagca tgccaggtta
    16861 taaaaataaa ataggcctag tattgaaaga tgaagagatt ctcgtaaacg gcacaattaa
    16921 aaaatataaa aaatcactcg aatatgagta tttatgtaaa gatttaaaag cttatatcat
    16981 taatactgaa aacattacat ctattagcag agtaaacgaa atagtaacat ttgcaaatgg
    17041 agaacaacta gagatgggaa agagaagtat tgataaacta aagaatttta tgcaagaaaa
    17101 gatagaaaat gaatcatttt aaagaaaaca aagactcata tcttacctgt tagaagagtg
    17161 ttttcctgta gaagagaaca acccaagtag cagcctagtc gtttctatcc ttttttgtta
    17221 tgcactcttt ttgacattta ctccaccaat aacgaagggt acaataaaaa gtaataacaa
    17281 acaaaaggag tacagaaatg attgaattca tcaatgtaag taaaagttac gggaaaaaac
    17341 aagcattaaa agacttgtct ctctcgataa gacaagggga aatttttgga tttttaggac
    17401 ataatggtgc cggaaaatca actacgatta aaagtttagt tagtattatt gaaccatcat
    17461 cgggaacgat tttagtagat ggaatgaaat tgacggaaaa tcgattgagt atcaaacaaa
    17521 aaatcggtta tgtgcctgat tccccagata tttttttaca attgacggct ggagaatatt
    17581 gggacttgat ttcagctgcc tatgaattag acacacaaaa aaaagaaaag cgtttagcag
    17641 aattgacagc gctttttgat atgtatagtc atcaaaatga aacaatcgca agtttttcac
    17701 atggaatgcg tcaaaaaacg attttgatcg gcacgttgct gccagatcca gatatttggg
    17761 tattggatga acctttgcaa ggacttgatc ctcaagcagc atttgatttg aaagaaatga
    17821 tgaaggctca tgccgcaaaa ggaaaaacag tcattttttc tacacatgta ttggataccg
    17881 cacaacagtt atgcgataaa ctggctattt tgaagaaagg tgaattgatt tatcaggggg
    17941 cagttagtga attattgaat ggctcacctg atgaaacgct agaaaagatt tatttgaaaa
    18001 tggctggaag gcaagcgaca ggagatggac cgtatgtata agcgacaatt attagaatta
    18061 attcgagtta atcttttata tgttaatcca cagctcacga ataaagcaag agagaaagga
    18121 aaaaagggaa agcgattaac tatctatctt ttgtctcaaa atcttttttc agggctgatt
    18181 tttttactga tttacggatt tgctatgttt gctatgaact ttgttaaatt gccaggtttc
    18241 tttacttatt acgtggcact ttttggtatg ttaggtttaa ctcaaagtat atcagtcatt
    18301 tataatatct tttttgaagg aaatgacctg caagtatttt tgcctctgcc ttttggacaa
    18361 gaacaggttt tttcagcaaa gattttggta gttgctttga ccatcattcc ttttgttttt
    18421 ccgcttctag tcatgtttat tttaaccgga tggcgagctg atctagggat tttgcttact
    18481 atcattatct caatcctttt gttttctcta tttttgatta ttcttttttg tctggctagt
    18541 ttgattgttt ttggtttggc tcgaacagca gtgtttaaaa aacatagaaa aacagtttct
    18601 agtatcttgc ttggcagctc gatgctgatc gcatttgctg gaatcatgtg gatgaatcat
    18661 caaacgggga ctattgaaaa tgagttaaca gatcggcatc cgatttcgat attattgcca
    18721 ttctatgatg ctgccagtca gccactttct caacaaggtt tattgggttg gggaatacta
    18781 gctatcacgg ctctgggatt tttccttgct gtaaaacagc tgatagtacc aaagcttaca
    18841 gagcaactga ctgattcaaa cagtgagttc aaaataaaaa gaacccataa aaagaaccaa
    18901 aatgtgcatc agcttttatt tagttacaat gctcaattag taaaagaacc taatttgatt
    18961 atgcaagttc tttcttcttc cttgttaact ccaatcattt ttattcttgc ttttgcccta
    19021 ggaggcgaaa taaaattaac tgatttagat aataagttaa tcggtgttgt tttcctggta
    19081 gggatcgcat tggctttctt aacagttaat cagacttctt ttatcagcaa tcttatttct
    19141 ttggatcaag aaaattttct gtttatccgt tctttgccaa tctctatgaa ccaatattta
    19201 aaagaaaagt tcagattcgg atggatattg cagagttttt taactggtgg gatcgcatta
    19261 ttaagcggac tgtcttttca gctgcctttg ttttttatcc ctagcttgct atttggttct
    19321 ttattcggct gctacttatt gtcactacgt tatttcgcta gagattatcg gttgctgctg
    19381 ctgaactgga ccaatattaa ccaattattt aacagaggtt caggaagttt gggtttagtc
    19441 gcaactatga tgggttcatt gatcatcagt attattctta tcgtcttata cggaatgttg
    19501 gctttgtttt atccattttg gttagtgaat attcctgtga tcggtttagt tctaatactt
    19561 tccgctctat ggatcgttta ttatcaacga acgttttgga aaaaatttga ataaagaaga
    19621 ggggccgtga caaaaatcat gtcgcagccc cttttttaca gatagagggt gttcaaaagt
    19681 cagtttctca gtattaagtc aattttatgt aaaaatgtga gaagctattt ttacaaaact
    19741 ttttttaata ctcataatta cttcttattg ctcctgcggt tacttgtcgc aatgtttgtg
    19801 agatattttg tcatcgctca aggctgaacg tctctttcac aaccttttct ttgttacact
    19861 tcgtttattt aaaaagccgt ttttttcgtt tcatcatgat tgcgtcacgc tttactttga
    19921 aattacggat gttatggtta aagacttctg ataatacaag acctaaagcg attgctccag
    19981 caatcataat tgcttggacc gcataatgag ccgcttctcg ataggattca gtaacgagat
    20041 ttcgaaccgc ttgataagct aaaccaccag ggactagagg aaccatcccg ggaatattga
    20101 aaatcgttac gggcattttc aaacgtttag agaaaagatc gctgatgaat gctactccta
    20161 aagaaccaag caatgaacca aaagcagcag atccgcctat ttgaacacag atccagtaga
    20221 tcatccagcc aaaagcacca gaaagaccac aacaaatcaa tgaacgccta ggtacatttg
    20281 taataacggc aaatgccgca gtcgctaaaa aactaaaaga aaactgaata aatatcgtcc
    20341 ccatacttgt gttcctttcc taataaaaaa gctggaaaat aaaagcaatc gcaaaaccga
    20401 tcatcgtagc agtcatcatc gcttctgttc cgcgagaaac tcctgagaca taatgtccag
    20461 ctagcaaatc acggatagcg ttcgtaattt gaactccagg aactaaaggc atcacacatc
    20521 cgataatgat tagatcctga ttgcttccta agccaaaacg tacgctgtag atagcggcta
    20581 tgccaatcaa taaagaagat aaaaattccg ataaaaattt gattctaaaa aatttcaaac
    20641 tatatagata agctgcgtat cccaatcctc caatgactaa agtcacaggt aaatcggtca
    20701 tctttccgcc aaataacacc ataattgttc cactgatcac tgccgcgcta acgatttgca
    20761 accagacagg aaagaaagaa cggtctcggt cgattgcttg cagttcgcag taaagttctt
    20821 ctaatgttag ctctgaagca acatatttac gtgaaagatc atttactttt actacttttt
    20881 ctaaattaat cgaacggttg gtaatttgtt ccattcggat ggtcgaggta cgatcaagac
    20941 caataaagag accggtttga gtgacatagc tgaccaaacg gaaatttcca gaagctaaag
    21001 caattcgact catcgtatct tctacccgat acatctccgc attgctttcc atcatgattt
    21061 tcccagcgag taaacaagtg tccagcaaca gatctaattc ttttcccgtc atagcatctt
    21121 ctccaataat tgattgatta gttttatttt actacaaaac ataccagaag cgtaaagaat
    21181 aaaaaaactt gaggaaggaa taaaagaggc gtatactgtt tttgtattgc gggtgtagtt
    21241 tagtggtaaa atcccagctt cccaagctga tgtcgcgggt tcgattcccg tcacccgctt
    21301 aaaataggtt gtgaaaaagc tgctctgcaa caagtaataa gaacagccaa gcaaaaacaa
    21361 cttcttatgt ttttaacttg gatggactta ttaccgcaga tgcaagcttt tgcgcaccgt
    21421 ttaccaagcg gttgtgaaat cagtgtattg tcttgagtat gaagaaaatt tttgaataat
    21481 aataaatacc ttacagatag agtggtgact gattagagac gaggaatccg tctctttttt
    21541 gtatttttaa gccatcttaa aacaggtttt attttttgct gtttctattt ctttctagta
    21601 tttatttata ggggaacata tgttaagatt tagggagctg ttagtaaagg agtaaagaaa
    21661 tgagcaaaaa aacaaccaag gcgatcgtgg ggatcgtcgc tgctgtgatt gcaggggcat
    21721 tcggtgtttc caccacacaa aaagattcag atatctttca gcagattaca actatttttg
    21781 attccacacc acaagcttct caagtagcgg atgtgccaga atatgatgga aaacatcaag
    21841 aaatagaaat caatgggaat cagccggaat ttacaaaaga ggatcttagc ctttccaaag
    21901 gaacatggga aagctattca aatattgata aattgaacag agtaggacaa gccaatgcta
    21961 tgcttggaaa agatttgttc cctactgaaa agagagagcc tttgtatatt gacccgacag
    22021 gttggaaaca aaagaaatta agtgacgggc aatggttata taatcgcagc catttaattg
    22081 gtttccagct gactggtcaa aataacaaca ttaaaaactt gatgacaggg acacgttcgt
    22141 tgaatgctcc atacatgctt gctcacgaaa atgatattgc ggcatatatc aaagaaacaa
    22201 atcatcatgt acgctaccgt gtcactcctc attttgaggg gaatgaactg gtagccaggg
    22261 gagtgcaatt ggaagcagaa agcattgaag acaaaaaaat tgaattcaat gtctttatct
    22321 acaatgttca agatggctac acgatcaatt atgagacagg acaagcaaca aaaacaaaaa
    22381 attagtagca gctattcgaa ttttttatga atattatgaa aaaattgtgt aaaaacatac
    22441 attcaaagaa atatagcgta tactttatga aaagagtact tttgataaag ctacagaaaa
    22501 aaggaaaaaa acatacaaat agtgtttctt aatttattcg gaagtttgga atatttgttt
    22561 gtagttttcc ctttcttcga gtaaaataag gttgtagaag gtaagctgga attaccttgc
    22621 gggaaagagg tgtagaatca tgggttttac agatgaaacc gtacgttttg gttttgacga
    22681 tagtcgcaaa aaagaagtga gcgaaacatt agcgattgtt tatcgggctt tggaagaaaa
    22741 aggctacaat ccaatcaatc agattgtcgg ctacttgctt tctggagacc cggcctacat
    22801 tcctcgttat cgtgatgctc gaaatttgat tcgccgtcac gaacgcgatg agatcatgga
    22861 agtaattgtc aaggactacc tctcaaatca tggagtgaat ttatgagagt aatgggcttg
    22921 gatgtcggtt ctaagacagt aggtgttgct atcagtgacc cctttggctg gacagctcaa
    22981 ggagtagaga tcattcggat caatgaagca gaagaagagt ttggctttga tcggttgaag
    23041 gaattagtag cacaatatga agtagaccgg tttgtagttg gattacctaa aaatatgaac
    23101 aattccatcg gaccaagggc agaagcttcc atgtcatacg gagaaaagat caaagaacta
    23161 ttctccttgc cagttgatta tcaagatgaa cgattaacca ctgttcaggc agaacgtatg
    23221 ctagtagagc aggcaaatac ttcaagagcc aaacgaaaaa aagtcatcga taaattagca
    23281 gctgtgatga tcttacaaaa ttatttagac ggctcaggta agcaattatt ttaataataa
    23341 aagaaaagag gtaatcttat gacagaacat aaccattccc acgaccatga aggacacgaa
    23401 cacatcacat tggtggatga ccaaggaaat gaaacattat atgaaatcct actaacagtt
    23461 gacggacaag aagaatttgg acgtaactat gttcttttat atcctgctgg tgtttcagaa
    23521 gatgaagatg tagaattaca agcttatgca tacatcgaaa acgaagatgg aacagaaggc
    23581 gagttagaac aaatcgaaac agacgcagaa tgggacatga ttgaagaagt attcaataca
    23641 ttcatggcgg aagaagaaga atagactata aagctaggag aaaccttgat atgatagggt
    23701 ttctcctttt tttatttttt actgtatgcc atattgtatg ccatctagtc aatatttaag
    23761 tgttgtacta atttttcaac agtcttttct ttcgtttctt ttgccaagtg accgtaacaa
    23821 tcgatcgtct gactaatttt tgtatgccgt aatctagttt gaacttctac catagtagct
    23881 ccagcgtcca agagcattga agcatgagtg tgtcttgcta catgcacacc gagaaatgga
    23941 accatagctt tttcacaaat agtaatcaat cttgcataaa tagcgtggtg tgtgattagt
    24001 tctttataga taccacaaaa aatcatagtc ggatcagtta caccaagtgt cagcatatat
    24061 ttccgctgat taatctgcca tttttttaat atagaaattg ttctttcatc tagtggaaga
    24121 accccagcac tacaatcagt tttaggatca ctgattttat agccattttt ggattggctt
    24181 agtgttttat tgatggtgac cgtattttct tgaaaatcaa tgtctgacca attcaatgca
    24241 agggcttcac tgatcctaac cccgctataa aagagaaagc gtagtaacgt tttatcaaag
    24301 tcgtttcgat aagtttcagg tttgctgttt aggtaatcaa acaaggtgat cagttgttct
    24361 ttactgtaaa ctttgacctt ttctttatgc ttagtggtgg ttcttttagg cattaatacg
    24421 ttgtctagtg gattagtctc aataatccca agattgatag cgtagctaaa aatacgctta
    24481 gaagttgaat gaagtacctt gtattggtca gtagtttcag cccagctatt tacaatttgt
    24541 tgggcttttt ttaccgtgac ttcattcaca cgaagatttc catattttgg aagaatccac
    24601 tttctaaact tgatttcagt tttcatgaag gtggcttctc ggacagtggt tttatatgtt
    24661 tctagccaca agtcataaac ttctttaaac gtttcgttgt tcgctttttt aataccgttt
    24721 ttatcgtagt ccacttgcaa gcgtgacaag gcaagctggg cttctttttt tgttttgtaa
    24781 cctcgtctac gaaccttatc aggtttgcca gtcattttgt tcattccaag ataggcttca
    24841 tagagccaaa atttaccttt tttagtttca tattgcttga atgttgccat aatagttttc
    24901 cctccatagt gtagcaagcc gtgggggcgg ttggaggagg cagtttatta ttattttgaa
    24961 tagtgtttat ttagctcagt aacaagagct gtgaactctt ttagaagatc attttcataa
    25021 aattcttgat actctttttt ctcatctgta tttttttctg aatcattaat taatgagtca
    25081 tatcgtaaaa gcgtatttag aagagctgcg agataagcaa ttggggtact cccgtcagga
    25141 aattcaattc gagatcctgt tttaagatat tttattgcgt ttgttaaata aatcttctgt
    25201 gagacagtca ggttatcttc ttcgatgtta ttgatagcat tagaaagatt agaatcaatt
    25261 atagagttat ttttttcaat agtttttttc aattgctttt caagcacatt tcgcttaatt
    25321 tcgggcatca tatgcatatc tcttaatgta taagatccgt ttaatagata ggtagtggat
    25381 acatctaata cctttgaaag ttgtttaagc ctggtgttat tgggaagatt atagccattt
    25441 tcccaattac taacggcacc tttactggcc ggtggggata atttacctcc aagttgttcc
    25501 attgagagtc ccttttcaat tctagccagt ctaattcttt gtcctgtctc cactgcttcg
    25561 gggtattttt ttctagccac attttcacca ccattcatat attttctcta ctatatcacg
    25621 atttaaatat gtgtgaaaca taaaagttca aaaaagtatg ttaaaattct tgcaaatgaa
    25681 aaggtatgat ggtatattga gtttataaga ggtatagaaa tgtattcaag agcctcttgc
    25741 atttttttaa aatctttgta tagaaatgta tgctaacgag gggggataaa tatggaatta
    25801 aaaattgaca aactcacgct tgatgatcca gcttttaaaa ttattgacga tcgagttgtt
    25861 caacaagtag agcaaactca aggaacgtta ctttcattat tagaaaaaaa gtaccagttt
    25921 ccaaaatata tgaacaaggc acaagctgct aagtatatga acgtttcata caatactatg
    25981 atgcagaaat atgttcctaa cggtttaaag ttgattatag ttgatggagt cgtaagaatt
    26041 tcacaagatg aatgtgatcg ctttatggaa gaataccaaa aataaacgca agccgtgggg
    26101 gcaaagggat taataggagg aaataataat ggaatcgaca caaaataaag caatcgaaaa
    26161 agtattatca acaattctta cagaagacac agcggcagaa ttagcaaact tggaaggcaa
    26221 agcgctagaa gaaacgtttg aatgtttgta cgaacaaatg gactatcaaa aattgctacc
    26281 acaagaacca acggtaagcg gagtattgcg tggcttgaac gatttagtac aagcagagtt
    26341 taaagaacga ctttctattg aagagtatca agaaattttg tatcagcaag ttgagttgtt
    26401 agcgagcttg ctagggcttg aactggagga cgttgaatga aaactgaaat ttggaacgga
    26461 cacattataa gatttgtcga tattaatgat gaatggtggg cagtggcgaa agatgttgcg
    26521 gaagcgttag gtcttaaaca ggttactaga gccattcact ctttgcctaa agatggggtt
    26581 actactagta aggtcatcga ttcattgggc agaacacaag atgtaaacat catcaacgaa
    26641 aaaaaatatt taccgcatgg cattcaaaag ccgtaaaaaa gaagccgagg catttcaaga
    26701 ctggattttc gacatcatca aagaactacg ccagtccaca ggacttgaag gctttcaagt
    26761 attccgcatg ctagacaaag aacaccaaaa agaagcaatg actaaattaa gccacgctat
    26821 tactgaacca aaaccagtag actacattaa agcgaatgtg atagccaata aagctgtatc
    26881 aactatttat ggtcattcca aaatggtaaa aaagaaagat atgactcctg aaatgttggt
    26941 tgatcgtgaa cctattttag atgagacagt agaattaatg actgttaaag aaaaatatgg
    27001 gttgcagttt tcagtgagtg agaaaattta taatcgttct gctgaattgc agacaactta
    27061 ggagcattaa catgatcgag aacaaagaaa aagccttatc cataacagtc ttggcggaca
    27121 ggataaaggc aacttaattg ggataaaacc cgatattctt tgttccgatt ataccatatt
    27181 aaaaaatcgg agggaaccat tatgaaacga aacttaatta taggaagcat tttaatcggc
    27241 ggaattttcg gcttattacc attaattgca aaaatagcta tctttgcagg attagcgtta
    27301 tatctcttca ctgcttatga cgagtacgac tatcaattaa gaactggagg gcataagtag
    27361 atgtacaaaa caaaactatt aaaccaactc gatagccttg aattagagga aattaatcaa
    27421 gggatcgctg aactagaaaa taatatcggg aaaacctact ttggaaattc attcaatgaa
    27481 aaactaacag ttttgtatgt actcaaaaaa catgcagaac acaaaataat ttgtcgagaa
    27541 atcaacgagc taaaaaatca gattttaacc gcatggttaa acattactga tatgcaagaa
    27601 gcaagggtga aaacatttaa tacatgggta aagtatcaga atcaattaaa aggtgctgaa
    27661 tttgttcggg atgggttgaa atacgaactt gagcagttga agctcatgga ggtgtctgaa
    27721 tgatttatac cagtattttg aaaaaggagg agaggtttat tggcaaataa ttatcaagca
    27781 gcaacggaat tacaaaagtc gggatggtca atttatccct tatctcctgg aactaaaatt
    27841 ccaataaaag gctctagtgg ttggaatgat gcaactaacg attctaatca aattaatgaa
    27901 tggtggacgg aagatgcaac tagaaatatt gggttaatgc ttgaagatca tcaaatggtg
    27961 gtagttgacc tagatcaaca ttctgaaaca cgaaacggcg ttgagaatta taaaaaactt
    28021 gcttcaatgt atgatccatt tccttctact tatacggaaa tcacaccagg taaaggaatc
    28081 catttcttct ttaaaattcc tgatggtgta attatccaac aagaaacagg tgcatttgct
    28141 gatatcttcg ggcgtgatga taaaggtaaa agtttaagcg ggattgatat tatcactaaa
    28201 ggagttccaa tagcgccaac tatgattatt tcaagaagtg ttgggagagc atatgaacct
    28261 attgaaaacg tatctctaaa taatattgca ccagctcccg attggctagt gaacctactg
    28321 ctaaaaaaac cgcaagaaat aaagactcaa taccgacccg tagcaaaaac agggacagca
    28381 aaaaaattag atatgattgt tcaaggcgct ggcgaaggta gtagaaacga tcatttaact
    28441 aagttatgcg gttggttact atggcacggt gtagataatc aaactttagc agaattgatt
    28501 tatacagcaa atgcgtacaa tgaaccaccg ctaaaagata aagaagtgaa tcaaattatt
    28561 cgatcgatga ttaaaaaaga tttgaggggg aaagctcatg gctcataagc ataaattaga
    28621 tagtatttta gactttcccg aagccagcga gcgtgaagac aatatcattg aattgaaaac
    28681 ctggatgtca cgattaagat gcaataaaga cgatcagatt aaaagtaaca gtgttgtgaa
    28741 tgcagaattg attttaacca atgatagcaa tttagctgga acaattgctt ataacgaatt
    28801 tagcggatac attcacctat taaaagattc tccttggatc aatcgtaccg ctggagaatg
    28861 ggaagacagt tttgaggatg ccttaacggc atatattgaa gaaaactaca atgtagtttt
    28921 tgatgacaac aaaatacaca aagcagtagt aaatgtggct agaaagaatg ttttcaaccc
    28981 agtaaaagaa cgtatcgaaa aagttaaatg ggatcaacag cctagactgg aaacactgtt
    29041 tattgacctt ttaggggtag acgacaacct ttacacacga gaagtaacaa aacgttggat
    29101 agtcggatca gtcgcacgta tctataaacc aggaataaag tttgagatcg ttccagtttt
    29161 ggatggaccg caagggattg gtaagagtac cgttccagca ttactttaca cggatgattt
    29221 tttcaccgat tcattagatt cgctaggtga aaagaaagat gattatatgc agcttcaagg
    29281 caatgtaatt attgaacttg gagaattatc ttcaatgaac aaaactaaaa ttgaacagat
    29341 aaaaaacttc atcagtgcca agatcgataa aattagacct ccttatggtc ggaatgtcat
    29401 agcttgggca aggcaatgtg tatttattgg aacgtcgaat gatgggcagt atttgaaaga
    29461 tgatacagga aaccgccgtt tttatccttt gccttgtaag aataagccaa agatgaatcc
    29521 gtttaaaaca aaggatgaat attttcttca agtgttagct gaagcaaagg tgctttttga
    29581 taaaggacaa cgaatctatt ttagtcccga tgaagataaa gaagtcttag aaattgcaaa
    29641 agactatcaa gaggatgcca agatggagaa tccaattaaa gaagcaatca ctaaatattt
    29701 ggaaatggaa atcccgtata aatgggaaga agctccagcg tgggcgagac gttcttatta
    29761 tcagaactat cctgacagta aatgtaatga gaaaaattta cagcatttct ataatggagc
    29821 tactatgcaa caagagtttt atttagttga tagcgtactc accgctgata ttttggaagc
    29881 tgtttttgat aaacaagcaa aggatttatt gaatggtcga tcagatgcag aaactaaaaa
    29941 gattgccttg attattagca gtattcctgg ttgggaacgg aagcaactgc caaaaagaaa
    30001 taaacgacga ggattttaca ataagtcaaa tgcctatgaa aataaaaatc gagctggaaa
    30061 gtacaaaaag taacgggtag taacgggtca gtaacaccta gcccgttact agtttaccct
    30121 tactgcccca agggatacag caatttggta acggggtaac accttatttc cttaaaactt
    30181 ttgaaatagt tagctaatat gctggggaat aatgttactg gattttaccc gttacctgtt
    30241 accaaaacgc tagaaccctt gtccccgttg ggattgagtg gtaacgggta cctgttacgt
    30301 aggtgttacc acgtgttacg aatcaaggag gaaagtaaat gctcaatatt atttcaacaa
    30361 acaaagcacc gaactttcaa tatacagatg aaatggatcg gtttctaatg aacacgctgg
    30421 catttagtgt gggattggta acagaagatt attccacatt tgatccagaa gtattaaaga
    30481 taatggaaga agaacctgat tggctgcagg agtcagtagc gtggtgtcaa tcgctagtag
    30541 tgggatcatt ggtagatagt ggcaactatg atgatacagg tgagctaatg gatgaattta
    30601 attgtctgct taacctatat gatcgagcga gacaacgaga gcttacatcg aatgaggata
    30661 atttgttttt aaacatccat gataagttct tggctttgct actaacagat gatgaattga
    30721 taactaattt attggaggta gaataattat gcatatggaa agtattagat acttcgatgg
    30781 tgagaaacac attgagtatt caaacactca agaagatgta gactttatta gttttgagga
    30841 agataaaatc actaaagtta attttaaaga cggaacgtgc ttgaagatag tttcgcctta
    30901 tattgaatac aaatcaaaat gggaacaaga tgattctgac gaacgagatc gctttggttg
    30961 gtaatctatg gcagttaaaa aacaatgtaa tcatgctgga tgtaaaacat tgattgatta
    31021 taggcagaag tattgtggga agcataaagc aaagcaaacg gcaattaagc gtgaagaaag
    31081 aaagcaaagc gaaggtaaat attttcaatt ctatcaaagt agaacatggc gaaaggcttc
    31141 atacttgtat cggttaaatc atccagtatg tgaggattgc ctagaagaag gcttgataag
    31201 gaaagctgat gttgtagatc acaaaattga actaaaagat gattggaata gacggttaga
    31261 tgaaactaat tttcgttctt tatgccatgc acaccataat tccaagacag ccaatgaaag
    31321 acaaagacga gaaaagagta ccctttgagt taagggggca tagtgtgaaa cttactgaca
    31381 atcgatgcct actcattttg gtacaaataa ccgttgtgaa aaggcataag ggtaattaca
    31441 aataacgatt acacttgtaa tcacaagtga aaaagtatat aatgaaagta ggagatttat
    31501 tgaaaaatac aattgttatt actgataaaa cagggaaaca gcgcaccatt gagttacctc
    31561 attttggtca agtgaccatt caaatgcaga acggaaaaat catttatata gataaattag
    31621 ataaagaaaa attctgatcg aaaaacgaag gaatgtgagc ttaattgctt acgttccttt
    31681 ttcttttgtc tgaaaggagg acaacatggg acaccctaaa atattacacg atacaaaagg
    31741 caatatatca agtgaagaaa aagcaatccg tgtggacgct agagaagaat tgttcaagca
    31801 gcaaccatta ataaatatca cgccccctga ctggatggca gcgagcgcta gaagtgaatg
    31861 gaatcgtatc gtaccaacat taaaaaaaga ttatccattg agtgaagcag attatggttc
    31921 attggtagcc tattgtttag cctttgctcg aatgaaaaca gccgaagccg agataagaaa
    31981 atcaggtacg tttatcacat gcgaaaacgg agtaaagaaa gccaatccag cggttcgggt
    32041 tcaatcacaa gctatgagtg atttgaaaaa acaagccacc tcactaggta tgaccttaga
    32101 atcacgatca aaactagctt tgaacaaggt taaaaatgat gaacccgaag acccgttcaa
    32161 agagttgatg aattcatgaa tgattacatt gagaaagtcc tatcaggtaa gctgattgca
    32221 cccaagaaaa ttatccaagc gtgtgagcgt catataagcg atttggagcg ttctaagtca
    32281 gatagcttcc cttatgtgtt cgatgaagaa caagccacca aagcgattaa attcattgag
    32341 ttgctaccat ctacggacgg taaagcaatc aagatgttag gatttcaaaa attcattcta
    32401 ggcagtcttt atggctggcg tactaaagaa gggaattaca ggcgattcaa tcgagcgttt
    32461 accagtatga gccgtaagaa tgggaaaacg tatatcgcaa gtggcatggc tgccaatgcg
    32521 ttgattatgg aacaagaacc agcagaagca aggcaagtat tgtttgtaag taacgctttg
    32581 aaacaagcta aattgggcta tgatatgctg tctaattcac ttagaaacgt ggtcaagtct
    32641 agtaagtttt taagaccaca actgaaaatt atgaactcta agattcagca cttgccctct
    32701 aattcgttcg ctatggcact ggctagtgaa accagcacgc tagatgggtt tgcaccaaca
    32761 accgcaattc ttgacgagtg gcacgaagca aaaactcgta aaacgtacaa cgtcattaag
    32821 tcaggaatga cccaacaaaa gaacggctta ttgtgtgtta ttagtaccgc tgggcttgat
    32881 ttaaacgttc ctatgtacga ggaatactta ttgttagatc gtgtgctaaa aggcgaagaa
    32941 caagccgaca ggtactttat agcgatatgg gaattggacg atcccgaaga aattcacgat
    33001 caagagaaat ggatcaaagc caatccgatt tttgaaagtg aagaaatcaa aaaagtaatg
    33061 attccaacca ttcaagatga tgtgaacctt gctttgaaac aaaataacct taattctgta
    33121 ttggtgaaaa acttcaattt atggagacaa gcgagtgagg acagctatat gattgctgaa
    33181 gactggcagg caaccgaagt agaaccacaa gatattacag gcaagcccgt ttatatcgga
    33241 gtggatttat ctaaaacaga tgatttaact agcgtttcat ggatcgtacc gctagataac
    33301 ggcgaacttt attgtgattc acatagcttt gtagccacca aatatgggct tcaagacaaa
    33361 gaaaagcgcg acggtttgcc ttatcgagaa ctagaaaaag ctggtgagtg ttccattact
    33421 caattagaaa gtggaatcgt ggactatgac caagtatttc agtttattca agatttgatt
    33481 caagaaaatg atttggaatg tatggggatt tgttatgacc cgtataacgc taattcgctt
    33541 atcagtaaag ctgaaaaagc caactaccca atgttagaag taagacaagg aacgattact
    33601 ctaaacgttc cgacccgaac ttttagagaa caagtttatg aaggcaacgt tattcacaat
    33661 aaaaatacga ttctcaccca tgcagtgaac aacgctattt taaaaacgga taacaacggc
    33721 attcagatta ataaatcaaa gaacagtaac aaaattgatc caatagctgc attaatcaat
    33781 gcctatgtgt ttgcaatgga ttacttcacc acaacggaag gagcgaaagc agacaatgaa
    33841 ttttatacaa gtgaagaatt ttctttctaa ttacattcat accgttcttt tacttcttgg
    33901 attggtgtgt gtgttggttg ctatcacctt actaacaaat gtctactatg gcttgttagc
    33961 gctgggcata gtgcttattg gggtagcggt catgctaaat acagaacaga agggaggtta
    34021 aaagatggca ttttttaaag cgagacaaaa tacaacggga gatcctttcc tacaacatgt
    34081 ggtatcaatc caatcggatg attacaccac cagctttaca agcgttcgtg cattaagaaa
    34141 tagtgatgtg tttgcagccg ttcgaattat tgctagtgat attgcttcaa gtccgattca
    34201 attggtcaaa aacaatatgc cacaagctga taatgaactg gtgaagttac taaacgagaa
    34261 acctaattca gaaatggatg gttggcattt aaagtttgct ttggcggtca atatgttgct
    34321 aaacggtaat agctttgcag agattaaacg caacggtgaa aaggtagaag aaattcactt
    34381 attacctaac tcaagtgtaa cggttactca attagataat ggtacgttgt cttatcagat
    34441 tggtgataaa aaaagacgtg tgaagtctag cgatattttg cacttcaaat atttcaccca
    34501 agatggttta acaggattac caccacttta tgcgttacgt gatgaactga aaattcaaca
    34561 agctggcaac cgcacattgc acaatttctt tactcgtggt gtcagtgggt caggtatttt
    34621 gaaggttcat aagtcagatt tagacggatc agcaaagaac gcaattcgtg aaaagtttga
    34681 agaagccaac ggttcaagta gtggagataa tgctcttaga acgatcattc ttgatgaaac
    34741 aatggactac aaaacattag aaataaacac cgatgttttg aagcttatca attccaatga
    34801 ttggaacaca aaacaaattg ccaaggcgtt tggtgtaccg attgagcgtt taggcgttga
    34861 aaatgaacat tctagcaccg ttcaaagtaa tctccagtat atccaaagta cgctgattca
    34921 ttactttaat gtgtttgtga gtgaattaga tacgaaactt gaaaccaata tccgctttaa
    34981 ttccgatcag ttactagaga ctgatcctga aacaaaagta aaaaatgtat tggatcaggt
    35041 caaagggtca cttctcacga ttaatgaggg gcggtcgaaa atggggctac cccccatgga
    35101 tggtggcgat cgtttactag caagtttgaa ctttacgtat ttagatacgt tggagaaata
    35161 tcaattaaaa gaacaggaag gagttacacc agttgaataa tgaagaagaa aaggaaaaac
    35221 ggctgacaga agaagctgag ctaacagccg attctcccaa agtagagaaa gaaaatgaaa
    35281 aacaaccaac agacggcaaa actatttcag gctatgcgtt gaaattcggg caaccgtcaa
    35341 aagatttagg cggctttgta gaagtgatta cacccgaagc attaaaagag gtggatttat
    35401 caaatgtgtt cttattatat ggacacgatt attcaaagcc actagctagt gtcaaagcag
    35461 gtacgttgaa attgaatgtc gatgatacag gattacattt tgaagcagag ctaaccgaca
    35521 cgacctattc aaatgatgtg tatgagaata tctcaaaagg ggttgttgat tctatgtcct
    35581 ttgggttcgt gcttggatta gattcattcg acaaaaaaga agatggcaca attgaacgat
    35641 caatagataa aatcaaagca cttaatgaaa ttagtgtcgt gaccgttccc gcttatgatt
    35701 catcaaatgt ccaagtaaat aagcgttctt acgaatcgtt tatgagtaac aaccaagcaa
    35761 aacaaacaaa caatagctta gaatccactt ctaaagcaca aaaggagagt aataacatgg
    35821 aaaaaacttt aatcgataac gaaaaaacag aattgcgtgg gtatgaagaa tatatccgtt
    35881 cacaaggcga agtgcgtgat ggagtcacta ctgtaaatgc agcggcagtt gttcccgaag
    35941 aagtaatcgg tgaagtcttt gatttgaaac gttcaaatta taacttagct caatatgcaa
    36001 cagtaaaaac agtatcaaat ggacaaggta aatatccagt agcaactaac caacaagcag
    36061 tgttagcaac aaaagctgaa cttgctgaaa ttggtgatat tgacgctgaa atgtttactt
    36121 cagttgatta taaagtagaa actcgtgctg gtaagattgc cttatcaaat gaggttgtgg
    36181 aagattcagc agtgaatatt gtacaagagg tcaaagatca gttagcgaaa ttggtagaaa
    36241 acactgacaa taagcatatc atggatttat taaaaacatt cactaagaaa acggctgcta
    36301 cgttggacga tttgaaacaa ctatacaatg tggcattaga cccagcatta aataaaatgg
    36361 taattctaaa ccaaagcgga tattaccacc tagatacatt gaaagattca gatggacgtt
    36421 acattttaca acccgatgtg acagcaccta gtggtaaatc attattcggt atgccagtag
    36481 tattgattgc agatacattg tttgccaatc ctaaagctgg aacattccct atgattatgg
    36541 gggatattgc acaatctatc tttgttgctc gtagaaatca agtaacgact caatgggaaa
    36601 aattcgatta ctactcacaa ggacttgcag tgatcgttcg caacgattat aagaaaattg
    36661 atcaaaatgc ttcagtgtat attgagttta cgccagttgt aacaccaaaa gtatagaaaa
    36721 atattgggcg gcggtttatc ccactgcctt tttttcatta ggagagataa aatggtaatt
    36781 ttggatagca taaaaaaaag tatgcggatc gatcacacta ttgatgatga ctttattcaa
    36841 caattgattg atacagcagg cgaatatata aaaagtgcta ttgatagtag cgcaacggat
    36901 aaagatatgg ataattatca gcaatttgat ttggcggtgt cattacttac tcaacattgg
    36961 tatttgaacc gtcaagaagc cagcagcgaa cggataccag taacggtaca agcattagta
    37021 caacaaatga gaggtgctta ttatgccaat cattaagaat gtaaatgaat tgactgagag
    37081 agtcaagttt aaaaagacaa aacgggtaaa agatgaagat gggcagatgg tggatagtga
    37141 agaaactgta tttgaatgtt gggctaatgt gcgttcacaa atgctaaaag acgtgcttgc
    37201 tagtgtaggt accattcttg aaggaacgtt gacgtttatt attcgatacg atcaagatta
    37261 tgaactaaca aacgatatga aagtagcttg gaaaaacaag agttataaaa ttatttcaat
    37321 caatgaagga acggcgttta aagattatac aacgatcata gctaaacaga tttcttagaa
    37381 tgattacact tgtaaacgtt gtgggtattt agtataatta aggtagtaaa tgaagggtta
    37441 gctgcctgaa ttttgcaaga cttagctagt cgaaatctat tgttggactg aaaattgtag
    37501 gtgtggttgc aaacatgctg gactaagaaa gatgatagat gatgaacgtt caattttaat
    37561 acaggcatgc taggactgat tggatggttt tggcaagctg attgtgtaga aatcaaagaa
    37621 cacgtctgtt gtggacgtgt tttttttgtt ataattcaaa agaggtgatt taatggacaa
    37681 agcagagttt acaaattttt attggaagta ttatctacat ttagaaaatg agtttattaa
    37741 taccacagat tttgtgatgc tcgatgagaa taatttcaaa acattctcta ttgaatatca
    37801 aaaactacta ctagcgattg gttcggagtg tgagattatt ttcaaagaac tttgcggatt
    37861 tgatagcagt agcaataaaa gcataactga ttttaaagct gttattaaat ctagcgaatt
    37921 aatgtgtttg gataatggtg ttagggttat gaattcttta acattgactt cactaaaacc
    37981 ttttggagat gggtggcctg aagatacacc agattggtgg aaaatatata acagagtaaa
    38041 acatggtcgt tcttcaaatt ataaggaagc aaatttggaa aatgtgttgt atgctttagc
    38101 aagtctatat ttattagagg aatatttgca taagaaagta atactagaag gtgaagtaga
    38161 ctttataagt ccagagtcaa atctatttac gttatcttgg gaaagaaaac attcgtcgat
    38221 gcaaaaagtg acgtttgaaa aagtggattc aaattatgta gctccactca ttgattttaa
    38281 agaacaagaa gaaatttaaa aacccccacg gcttattgaa gtttttgtat gccatattgt
    38341 atgccatttg gtttaaatcg cttgaaaaat agtgatagat aactctaatt catttagtca
    38401 taaacgctgt tttgataacc tttatagttc tttgatatgg gtttctcatt catggcggaa
    38461 gaagaagaat agaacaaaag aatgaattaa taagatataa aaaaagggat tgtgacaaac
    38521 gtcttgtcac aatccctttt tccaaataaa cgatgttcaa tcagctgccc ctcggcattc
    38581 gctcgaaaaa cggcgaaata tgaagaacta ttttgccatt tgtttctcta ataatcaggt
    38641 caaaacgttg acttcacagt ctcttcctta aacggtgttc tcctgccaac tcctcggtca
    38701 caagtcacaa tattcaacaa acatgagaag ctgttttttg aaattgttcc ttgtgactcg
    38761 gagctgaacg gcaggctcac gacctctttc ttaaacggtg ttcaaaagct tgcatctgcg
    38821 gtaataagtt caaccaaacg aaaattatga ggagctattt ttgtttggct gttcttatta
    38881 cttgatgcag gacagctttt tcacaacctc ttttcgttta gcactaaatt tccttaaaaa
    38941 gtagaaaagc tttcgaagcc tcgtttgttt cttttactgt ataataaaag aaaagagtaa
    39001 caatcgctaa aagatataaa caagagaaag gaaatacaag atgattggtc tgatttattt
    39061 tgtggtgatc gttctggcga acacagttgg cgctatttcc gggatgggtg gaggcgtgtt
    39121 gatcaaaccg attcttgatc ttatcggcgc ccattctgtt gcagggattt ctttttactc
    39181 aacagttgcg gtattcacga tgtccattgt ttcgactgtg cgacaagtat caagcgggaa
    39241 atcactgaat tggcagattg tcggttgggt atctagtgga gctgttgttg gaggagtagt
    39301 cggcaacatt gtattcgaag tttttttaca gttatttgaa aacgagaagc atgtgcagct
    39361 gatccaaatt tttttgacgg tattgacctt ggtttttgcg ttcttctaca ccaagcatca
    39421 tcagccaaaa tttcatttga cgtcatggac ttggtacctt atatgtgggg gggttctggg
    39481 ctttttagct agttttttag gtattggtgg tggaccagtc aatgtttctt tgttgatgct
    39541 gatgtttgca ttgccaataa aagaagcaac actatattct ctatctacga ttttcttttc
    39601 tcaactggca aaattggtaa cgattgcttt aacaagtagc tttatgcgct ttgatttatc
    39661 tatgttgttt tatgttatcc ccgctgctgt tattggaggt ttgtggggag caagatttag
    39721 cagggttttg tctccaaaaa aagtgacctt tatttttcaa gtaattgtcc tcgtggttct
    39781 tttggtcaat tgttacaatg cctttgtcat cttacaaaca ttaggagaat ctagactaac
    39841 gcaagtcaaa atcactgaaa catattgttc taaatgaaaa aaagagtata ctatgataaa
    39901 aaaattcatt ttaaaaaatc agaaattggc tggtgatttg gatgttacgg gaaatgcgtt
    39961 tagaagatgc agaagcacta cgtgaaatca atgcggatca attagggtat gatataccat
    40021 taaccgttac ggtgagacaa atgaagaaac tgctgaagga gccagagaaa aattttttct
    40081 tggtttatga agatcctact tctaaaaaag cagctggcta tgtacaagcg gagtcctatg
    40141 aatcgatttt tagcgatcca atgttcaata ttatggcact tgctgtgtct aaatatgctg
    40201 aaaaaagagg catcggaaag gctttgatga ctggcgtaga agaagaagcg aaaaaacgag
    40261 gaataacgac aataaggctt aattctgcag aatacagagt agaagcacac caattttatg
    40321 aacacatcgg ttatcattcc gataaaatgc aaaaaagatt tttgaaaatc ctgtaaatct
    40381 ttatcaaaaa aatacccgat caccaagccg atacttgatg atcaggtatt tttgtttttt
    40441 tgactaagaa agtaattgca tcaagaaacc agagatgatc aaaacgatgg caccaccaag
    40501 tcgattgccc atttgagcaa aagcaataag ttccatccga ttagctgcag ataagacggc
    40561 tacatttcct gttccgccca tcgagttgtt gcataagcca gcagtaatag ttgattcaat
    40621 tggatataaa ccaaacaaac gaccgacaaa tcctgaaaca actgaaatcg cgataacact
    40681 tgtcagacat aagacaacaa attgccatgt caaagcagaa gctaatacat tcagattcag
    40741 caacgcaata ccgataccgg caagaacagc tgctgtcaag tttttgacaa tcaagttatt
    40801 gaacatgata gctgcatctt cataatactc tggtaatagg ttggcgattt tacagatgac
    40861 aacgataata atcataaatg cgtaagcatg gactttagga acaaaatagt taccaatttg
    40921 tcctaagatg aagaaagtca atgataccat caaaccaaca cctaactgtg gaatggaagg
    40981 tttcacagtt cgaggttttc catcgccaag atcgcctttt tccattaatt taccattgcc
    41041 gttgaatttt ggcattgatt gtccagcacg agcaactaat gctgcaccga tgatagctaa
    41101 gacatttgtc attgctgtcg caggaatcag gcgggaaatg atagaagaag catccgtacc
    41161 taaaacattt gcataaatcg ttgataaagg aacggctccg gctccaacac caccagccat
    41221 cgcaggtaat gagatgtata aaacggaatt tgcaaaacca tttccgataa gcatgcccac
    41281 gagtcctacg gcaaaaaagg agacgaccat tgaaataagt gcaacgggaa taaaacgaac
    41341 agaagctttc atcaatagat tacggttcat accaaggatg ctaccagtaa tcaaggcagc
    41401 aatataaaag tcccaaaagc ccatattgct gacaaagttt tctgtggatt tcactacata
    41461 ttcaggtaag atcccaaatg tagcaatcgc agcagaagcg aagatcgcaa aaacggaacc
    41521 accacccaaa taacttttga cgatagggat ttttgtcccg ataaaatgaa ataaattacc
    41581 gaaaataacc aaaactgcga ttggtccaat catattcgtc ggtaatttcc ctaaagccat
    41641 tgcaatgatc aggacaagga ccatgatcaa ataaagtggc aaacttacgc cggtgatttt
    41701 tgtggaccaa aaaccttctt ttttcttttc ctcaactgca gttgcagttg ttgttttttg
    41761 tgccattttt acagatcctt tcttattctg tatcatatga aaaaagccaa agaaaagcga
    41821 caaaagagca ggagttggct ggccgctgtt ttgccgcagt cgcttttttc tttttagacg
    41881 tcatacaaag tttctgtatg ttcttttact ataacgatct taatcttcta aagatttata
    41941 ttcaggaacc catttagcag attcaactgc ttctttgata tccgtgattt cttcacgatt
    42001 caagttttgt gcgacaactg attttgcgac agtttcagca atcgtttgag aaaattcagt
    42061 gatttttgct actggaggca agatagctgc tcctggtttt gttacatcaa cgattccgcc
    42121 taatgctcga ctagcttgag aaatgatttc agcatttact cgtgtagctg ttgaagcaat
    42181 caaaccaagt cctaaacctg ggtacatcaa agcattattt gcttgaccga tttggtaagt
    42241 tacaccatta tattcaacat cagcagcagg gatacctgtt ccaactaatg cttttccgtc
    42301 cgtccattct attaaatctt ttgcttttgc ttctgccaat tttgttggat tagacaaagg
    42361 catgatgatc ggacgtggtg tatgagcagc catttctttc acgatttctt cagtgaatgc
    42421 tccaggttgg gtagaagtac caatcatgat tgtcggatgg atcgctttta caactgcttc
    42481 taagtttgtc aattcatcag cattagtgaa atctgagcgt ttgcgagcga atgggatttg
    42541 accaggagtc aatccttctg tatcttcaaa caataaacct tgtttatcta cttgatagaa
    42601 atgttggcgt gcttcttctt caggtacacc ttgacggatc atctcatcta aaaggatgtt
    42661 tgcgataccc acaccagcag taccagcacc aaatgtcaaa attatttgat ctttcaattg
    42721 ttcaccggat atattcaatc cgcctaatac acctgctagg acaacaattc ctgtaccttg
    42781 gatatcgtcg ttgaaagtag tgatttgatc ttcgtatttt tctaagatcg ctgcagcatt
    42841 tcctcgtcca aaatcttccc aatgcaataa caattctggg aataattcgg tagctgattg
    42901 aacgaattga tcgatgaatt catagtaagt ttcgccttct acacgagcat gacgattgcc
    42961 taagtataag ggattattca ataattcttc attattagta ccagcgtcga tcgatacagg
    43021 caaaacttgt gctggattaa taccagcagc agcagtatag accatcaatt tgccgatagc
    43081 gatgtcaaca ccgttcacac cccagtcgcc catacctaag attccttctg catcagtcac
    43141 aacaatcaaa cgaatgtctc gtccatctgc cgcgttcttc aaacttgctt tgatgttttc
    43201 tggttcgtcg attgaaagaa atgcagcatc ttgcggtttc aagaaaattt cgttgtattg
    43261 ttcgattgaa tccgcaacga caggatcata aacgacaggc atgaattcaa ctaaatgttc
    43321 gcccatcaat ttataaaaca atgtccgatt cgtattgaat agattcatta agaagatacg
    43381 tttttccaaa tctgtttgtt tgcttaagta ttgaccataa gcttgaacag attgttgttc
    43441 cagtgtttgg acagtacttg gaagcatacc agtgattcca tattttgccc gttcttcttt
    43501 tgtaaaagct gttcctttat ttagaaaagg attatttaat aagtttaacc ctgtaagcat
    43561 gaatgattcc tcctaagttt taatacaaac gaagtataga agtcagatga tgatatagtc
    43621 aaaaagagca ggtatgataa attttattta tatgtaatat agccaaaaga aatcaaaata
    43681 gcagtatttg ttctttttat atcgacaatc cttgcttgaa tactatgcgt atctcttata
    43741 tgctagagaa agaaaagtag aagaataagg gatagatgga atggataaat aggatttctg
    43801 aggaaaaaag cacatgatag cgttgatagg agtcacctat gtcaggtgat aaaaatacat
    43861 aagtagaaaa ttaagaggag gaagagaaaa tgaaagaagt tcaattgatt agaaaaagcg
    43921 aactatcaga aggcggttgc aatgcatgtg gcgtagtaga agcgacaagc tatacattaa
    43981 aattagattc caatcaagca ataatctctg aactgacagt aggcggtctt gtggacagtc
    44041 tggcgcttgc tgaaggtttt actggagaag atatttatga gatgttttca gaagtccgtc
    44101 agttaaaaaa aggagaaaaa tgcatagagg ttcatcatga gagcccgaat gtgaggttca
    44161 aacgtggtga taatgagatg atcttcaaga atcatgtgtc tgatcacact gaactatatg
    44221 aaatcgtgaa tcaaatactg tctgggattt ttgaattagg accttatgag ttcaaggaag
    44281 aaaacggtaa tccaaaatta aatgaagaat ggcaagaaac gattgaaaca caaagaaaca
    44341 atccacactt atttcaatag tcttccacag tatttcgtaa aaatgttgat gaaaaagaaa
    44401 caccgtgaat cagaggtcgt gaaaaacctg ccctgcatca agtaataaga acagccaaac
    44461 aaaaatagct cctcctattt ttcgtttggt tgggcttatt accgcagatg caagtttttg
    44521 aacaccgttt aaggaagaga ctgtgaagtc aacgttctga cctgagtatt agagagacaa
    44581 atggcaaaat agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat
    44641 tgaacaccgt tttatcgaga ggttgtgaaa aagtcgctta gtttcgagta gtaagaaaaa
    44701 ttttgtgaaa atggctttcc acatttttgc ataaatttga cttaataccg agaaaatggc
    44761 ttttgaacac cgtttattca aaaaaaggga ctttgacact acttttgtca aagtcccatc
    44821 ggttttttat ctatttttat tacaatcatt tcttccagag tagtgacatc tggaatggct
    44881 gaaatgtaaa cagattattt gcctgtatca atgtcgaaga gtaatataaa aagtgtaaac
    44941 gctatcatat tgttcatcat tcaaatttta tagagagaag gcattgagat ggaaaaaaca
    45001 tatcaagcag gtacaaatga aggaatagta gattttatca atatggaaga tttagaaatc
    45061 gcggcttcac aagtgattcc agctggtggt tatggttaca tcagcagtgg tgctggcgac
    45121 ttatttactt atcaagaaaa tgaacgggca ttcaatcatc gtttgattat tcctcatgta
    45181 ttaagagatg tagaattacc cgatacaact acacattttg acgaagaaat gctgactgca
    45241 ccaatcatca tggcaccagt tgctgctcat ggattagctc atgtgaaggc ggagaaagct
    45301 tctgcaaaag gtgtagcaga ttttgggacg atctatacag caagttctta cgcttcttgt
    45361 actttagaag agataagaga agcaggcggg gagaaagcac cgcaatggtt tcaattttat
    45421 atgagcaaag ataatggaat caatttggat attcttgaag tggccaagcg taatggagca
    45481 aaagcaatcg tattgacagc ggatgcaaca gttggcggaa accgtgaaac agaccgcaga
    45541 aacgggttta ccttcccgct gccaatgccg atcgttcagg cttatcaatc aggagtaggc
    45601 caaacgatgg atgctgtata taaatcttcc aaacaaaaac ttagtccaaa agatgtagaa
    45661 tttatcgctg ctcattctga tttgccagtc tacgtgaaag gtgttcaatc agaagaagat
    45721 gtctatcgat cattagaatc tggtgctggt ggaatttggg tatctaacca tggtggccgt
    45781 caattagatg gggggcctgc tgcgtttgat tcgttgcaat atgtggcaga agcagtagat
    45841 aaacgtgtac caatcgtgtt tgacagcggt gtacgacgtg gacaacatgt tttcaaagca
    45901 atcgcatcag gtgccgatct tgttgctatt ggcagacccg ttatttatgg attgtcttta
    45961 ggaggaagta caggagtcca tcaagtgttt gatttcttta aaacagaatt ggaaatggtc
    46021 atgcaattag ctggaacaca aacagtagaa gatatcaaaa aaataaaatt gcgtgagaat
    46081 cgttttattt aagaaataaa tgacgaaaaa aataggagtg cggcagatga tgccgtactc
    46141 ctatttttat agttcaagga tgtcactaat agaataattt gaaacgaaaa aataaaattg
    46201 aaatattgtt tcatacttaa taaaaaagga agaatattca tgtaaacgat tttattgttt
    46261 ttttctcttt tatacaaaaa gggtcataat ttcaagtaag cggatgaatt catgaggatt
    46321 ttttgcatac tgtctctact atacttaggt cactaagaaa aaggagtgat ttattatgaa
    46381 aaagaacatg attgggacat tattactttc aacacttctt ctaggcggct tggcaacacc
    46441 agcttttgct gagggtcaag cgacttcaaa aggagatatt acctttactg aaccaacaaa
    46501 taccgttgag cctcttaacc ctactgatcc ttcaaaacca gtagagccag cagatccgga
    46561 aaatccagca actggccaga caggttcttt aacattggat gtagttcctg aattgccatt
    46621 tggtacacac gagattgaaa gcggaacaaa aacgtatcaa gtagacgctt caaaaaacga
    46681 tacaccttat ctccaagtat cagatcgtcg aggtgtaggt gcagatggcc aagcacaagg
    46741 gtggaacgtg acagtttcgg tttcagattt tgtaaacggt tcacaagttt tgcaaggcgc
    46801 tgaattagat tttggaacat ccactgttaa aagtacgtca gataacgaat ccactggacc
    46861 aactagtcaa actgtaactg ggttgagtaa agcaagtgca gcgacaccaa tatttacagc
    46921 agcaaaagat caaggtctgg gaacatggct ttctgtttat gatccagcaa atatcacact
    46981 gaaagtgccg aaagcagcag ctggaacatt cacggctgat ttgacttgga acctcgtggc
    47041 tggcccagta gcatagagta tgaaataaat tcaacaaact gcggtgaaaa tactataggt
    47101 gaaggatttt ttaccgcagt tgttgttgaa aggatgtggt ggacaatgaa tcaaagtaaa
    47161 cgactgtttg tttcgttttt ttctatttta agtctatttt tcatttttcc gtcaatcagc
    47221 caagcaaagg attcagcagg agactttgga atcaaaccgg tatttccaga gaaccaaata
    47281 gataaagcaa tcggttattt tgatttatta gtggcaccgg aacaaaatca gacactagaa
    47341 gtaattatca gcaattcttc agatgaagaa cgaacatttg aggtctctgt caatccggcg
    47401 gtaacgagtg atggtggaac gatcgattat agtcaaaaaa acccaacgtt agatgagaca
    47461 ttgccgtttg atgtccgtga cgttttgctc attgcgaaaa aggaaatcaa tgtatcagca
    47521 catgcagaaa caactatacc tatagaagtg aaaatcccag caaaaagctt taagggacgt
    47581 gtattagcgg gtattcatgt ttcacctaaa gaagaagctg aaacagaaaa tgctacagaa
    47641 ggagcacaaa tcaaaaatcg tattgcttat aatctcgcag tcgttttaca agaaagtcaa
    47701 gagacgatag aaccggatct gaaactttta tcaggagatt tggacgaggt caacgcaaag
    47761 ccaactgttc agcttcgttt ccaaaatcct cagcctagga ttatcagcaa tttgatattt
    47821 acgagcaaga tcttttatga aaatcagctt tatattgaaa atacgtctaa tgaattttta
    47881 gttgcaccaa attcgaattt tcacttgaat cttgatttag ctggtgataa agcaaaagcc
    47941 ggcgattacc gcgcagaaat catagcaaaa tcaggcgaca gtaatgaatg gcgatttaca
    48001 caaaacttta cgatcaaaaa agaaaaagca caaaaagtaa atgaaaattc cgtttttgca
    48061 gtacaagaac aatctttccc atggctttat gcaggattgg ttgctgcagt tctagtgtta
    48121 tggttgattt tgctgttttt gtgggtccac aagaaaaaga aaaaaggaga aacaacatga
    48181 tgaggtgatt tcgttgaaaa catcgatctt attgggaggg attattgcaa gtttgctgtt
    48241 cttcagctgg caagagccag tccaagcaga taccaaaagt tcaggtacga ttacatttta
    48301 tgatctaagt ccagttccgc atccaagtgg ttcagtcaat ggcgcatcaa aacagcagac
    48361 acagctaccg atttataaag aatctaatca acatggcgta ttcccggaga cgaatgaaga
    48421 aaagatccgt tttctttatt tgatcattgg tatagaatta tggcttcttg cgtggttgtt
    48481 gttatggaga agaaaggaaa aggaggatga acatgttgct acaaaataaa ttttcatttt
    48541 ttcgctcctt cttttttact tcgctttttg ttttaagtat atttatcttt tcaccttcgg
    48601 cagaagctgt tggagcaacg cctcctgcca tttcttatga tccatacacg tatgaaaata
    48661 tcgtacctcc aaatggtgga cgtagtgcag tcaatggcgg gaagcttgtc caactaactg
    48721 gggctaacca attgcctaaa ttgactgcta cttatttgaa cgatggttca aatgatcctt
    48781 ggaaaggtgg cacggtccgt tttcattggg aaagccatgt gaaactaaca aatgtacttg
    48841 atttggtgaa tatcactgca caaggatttg catttgtggc gatcatcaat ttgccggaac
    48901 atgtatcaag cagtgatgta ttaaaagcaa ttgactggaa caacgcctac ttgtatattg
    48961 ccggtgcccc catcaaggtt actagcggta gtttattatc agcaggaagc cataccttgc
    49021 gttttgggat ggggtcgtgg gatacaaata ctctattggc agatattatt gctattatta
    49081 cgcgaggtat cccgcttcaa tttgatgtta cagctaatgt cgcgaagatg acagaaaacg
    49141 gagataaata tgatacgagt ccaaacaaaa ttttgaccaa gggtaaatta caaccttcta
    49201 tgtctaaaaa ggccgttttt tctgttgatt tttatgattc gaataatatt atccaagatc
    49261 gtatgttcaa ttcgatttta gctccagctg caggtagatt ttatcctaaa ttaactggcg
    49321 gaaacttgaa tccaggagca tatgcatttt ctgcaagtgc agagataaat acgtggaata
    49381 gttacatctc aacaagtgat tcaacaggaa aatataatac atttgctgat accacagaat
    49441 acgtggatgg aaataaccag aaccttccag gctctaccaa tagtcggaca ttgacgatgg
    49501 ggctgactga aggacgtttt gatcagttgc catttagtcg ctttgatcgc gtagtcaact
    49561 attttacagg aaaaaacgtt acacaaggag caatactgac tcatactcca gcaagcacaa
    49621 gtggattgaa tcagacagcc aatatcgtgt acagtgggaa agatgcgcaa ggcggattgc
    49681 tttctcctgt tgctttaaag gtattggagc agtacaagct agacggaacg gttttaccaa
    49741 caaacttaac agccgatagt cagtggggaa agctcctttc ttctgcatcg taccaagtca
    49801 cggccaattg gtcagcaact gaactaaaaa agggttcgat ccattacagg ctttattcga
    49861 aaggaaccca aaaattagcg acaggatgga cagatcaact tttccaaacg atccaatcaa
    49921 ataacggggg tgtaaataca gctacttcta cactacctgc attggcttca gggcaatatt
    49981 attttgatta tcgcttggtg gacgatgtac ttactaacat gtatccgtct tttgcgtaca
    50041 aatggcagtc tgaacaagct ggaatcacca ctcttcctca aataacagtg gctaattttc
    50101 catctgtgag tgcagatagt cagctaaaaa accttagcag acaacctgag acaggagatc
    50161 ccctgtctgc tctatcagga gatacgattc aagaaaatgt gacattcacg ttaacaaaat
    50221 ctggggatgc gataaccgac aaaaaaatca cgatctcact tcctgaaaat actacttata
    50281 tcaatggttc cttaaaatta aatggtacaa ctatcgcaga taccggcatt caacaaggag
    50341 tttctgtccc agcagatcta ttgagcaaaa taggagatac cattcatctt acttacaact
    50401 atcaattaaa tactgtagat acttctgtac aatccgtcag catactgaca aaggcagctg
    50461 tactttccag caatattaca ttagcagatg gtgctaagct tcctaaccca gttgtccaaa
    50521 catctgctaa aacaattctt gtccccaaac aagaattaac attagttaat gtaccagatg
    50581 attttacatt tggtaacgat ctccccaaac cgttgaagac aagttattat gaagcaaaag
    50641 gcgatttttc ttttgatgtg cgggatactc ggcttccaag cacgtctcct tggcaactga
    50701 cagggacatt gacttcttta tttaagaatg atcaaggtca agaattaagc ggaacaaaat
    50761 tatacttcaa tcattctgga tcaaaacaat tgattcagca aggtcaaaac acgttgattt
    50821 atgagagtga tggaacagct aaaggagagg ttctcgttga ctttcccgat accgatggtt
    50881 tactcttaga ggtaaatagc agtacgaatg ctcaacctgg cgcaacgtat caaggcatgg
    50941 tcacatggga actgacagct gggccaacca gctaagtgat tagaatttgt atggatctgt
    51001 gataactgtc acagatcctc tttttcaagg atgagaagga aacttctgct gttaaaatca
    51061 gaaatgcttg gaggagtgga cttggaactt ttcagtttgc ttgaaaaaaa tgaacaacgg
    51121 caaatcaaac ttttccaact tttattagag gaaaaaggag agatttccgt taataacgta
    51181 cttacccgct tatcagttga tcgggctacc ttgaaagaag atctgtttta tttacaagct
    51241 aacttggaaa atatcaaaca attggaaatt gttatccaag aagggaatat tttattaatc
    51301 agacatggaa atatagcagc agtcgatgtt tattatcatt gctacttgcg ctattctaca
    51361 aaatatcaga tacttcttta tctgttggaa aatggctcat ttgatcggca gaaacttgtc
    51421 atggaactta atatcagttc ggctactttg tctcgcagag tgaaggaatt aaatgattct
    51481 ttaaatgagt ttcatctgaa aataaaaagc gggcggctga ccggtccaga aagtcaaatt
    51541 tgttattttt atttccaatt attttggttt ggacgtcctt atcttgaaaa caaaaaagaa
    51601 tacagtgatt tatcaggaaa cactttttta gatctgctgc aaaaagagtt tagttttact
    51661 attacagaag aaggacgatt gaaatttgaa atatggcttt ccattatgaa gaagcgaatg
    51721 cgctgtacga aaaaatccaa accagattat agcaatcttc ctgttggatt gtttcaaacg
    51781 acacaatttt tattggacct ccatacattt ttgacccgtt acttctttca atatgccttt
    51841 ccttggaatc aaaatgaaac gttggttttt tatcttttca tgatcagtaa ctttacatta
    51901 gatacacata actcgcatgt ccaggagttt ttgataagcg aaaaatacaa agacgacgta
    51961 gtagctcaat tgaatcgaac gtttaaacaa tcgatagaag aatatttctc tttttatgtt
    52021 tttccagaag agatttcgca aaagattgcg ttgacagtga tgcaaaatca cgctcatttt
    52081 gcctatttta gaggatggat gaatattttt ggccaagaag gattaaaaca gcggttaact
    52141 gaagtagaag ataaacaatt cctggtttta tgtgaaagat tggtcagaca aacatttgct
    52201 attgttgatt ttactgaagt agacgaggaa aatgcccgct ttgaattatt tgctcgctat
    52261 gcatctattt tgcggacgct gatcaagcag ttagaattac gtctgcaaat tgcttatgat
    52321 cttccttatg aaaggctaat ggcggatatc gtgaaagaaa tcatccagga acaattgctg
    52381 aatacgatca aatatgattt agtcgaatac gagaaagaaa agcagtatga tatcattttg
    52441 actagccaat tgaaagagta cccgtcacag aagtccgcta aagtttttgt attcactagc
    52501 aacgaatata attatgattt cccctatttg aaccaatttt taaaagaatg ttatttagaa
    52561 aaattgaatt taaggatgaa taaaacatga aaatcgtgat cattggtgct tcccatgcag
    52621 gcatcacagc tgccctaaat ctaagaaaac ttcaaccgaa agcagaagtt ttactgatcg
    52681 atgaagatca taaagatgga ctaggctatg tttcaaatgg aatcaacctt tatttaaaag
    52741 gaaagatacg tagtttagct gaagttgccc ataacatgcg gactcttcaa gaaagtgggg
    52801 caaaactgat caccgaatgg agagtaactg aacttgatcc agacaaacat cagctcatcc
    52861 tcgcatccaa agaaggaaaa aacgagacca taacctatga taaattaatc gtagcaacag
    52921 gttcctctcc tgtcaccttg tataaacaaa ttgaagctga aaatgtctac acctataaaa
    52981 atctagtgca atctaagcaa gtacttgccg ctttaaaaga agcaaaagaa gtagtgatct
    53041 tcggtgctgg ttatattgga ttggaattag cagatgcttt gagaaataaa ggatacatta
    53101 ttcatctagt tgattatatg ccgaatgttt tatcaagata tttcgataag gatatgatca
    53161 acagttttca aaatcagctg caaactaagc aaatcaattt ttatccaaat gaattcttga
    53221 tcgattggaa aaaatcagaa gagaaagtag tatccgtaca acttctatct caagcaataa
    53281 aggcagatat ggtcattttt tctgcccaaa ctcgtcctaa tacgacattg ttaaaagaaa
    53341 aagtggcttt gtatgaggat gagactgtga tagtcaatga atatctgcag acaagtgatc
    53401 cggacatcta tgcgattgga gatatcgtcc cagtcagttt tgacaaaaat aaacggcatc
    53461 tctttttacc tttagttact cgagctgtac atatggcaag agcagtagcg ctaactttga
    53521 gtggtcagcc aaccgcttac gacctcagac aaaagataac agcagcagtc attatagact
    53581 actttttagg aactgtaggg ctgacagaag atgaagcgcc attcttggaa caaaataccg
    53641 gttcgtgttc aggagaattt gatctatttc cacaatacga tgaagaaaac aaaacagtaa
    53701 atgcaaagct gatctaccat ccggatacat tagaaataat tggcggacag ctgataagcc
    53761 aagaattctt attatcagat ttgaacctgc ttgcggatat cgtgaaacac aaaactacga
    53821 ttccacagct agcagttgag gattttggat ttctgtctga acacacctct cgttttcact
    53881 acctcaatga gttagctttt aaagtactag ctaagagagc aaatagcaat agagtagata
    53941 aaagactgtg agaaatatca cggtctttta ttgtgtgggg atataataaa tattaatcaa
    54001 tcgagaataa aaaattcata taatgaaata gcggaagaat tttttgagca taatattcgc
    54061 caaaaattta tcaagtgata aaattgttgt ataaaatgat tatttcagga ggaggagtta
    54121 aatgttttta gcattaaatg aaattatgca ttcaaagtta cgttatgcgt tagttgcagg
    54181 ggtgatgttt ttgatcgcct acctggtatt ttttttgact gggttagctt atggcttagc
    54241 tcaagataat cgaacagcag tcgacaagtg ggaggcagat tcgattgtgc tttcgaaaga
    54301 tgcaaattca aatctaggga tgtccatgat tactaagaag atagcagaag aagtcgaagg
    54361 tgggaaagtg gcgtatcttg cccagacacc tggagtcgtg actagtaaag acagtacaga
    54421 agaaggaaaa atcaatgtta gcttcttcgg tatcgataaa aatcaattca tcatgcccaa
    54481 tcttgttgaa ggaaaagctt ttgataacga tgatgaggca gtaggcgata ttagtttgaa
    54541 agaagaatat ggtctagccg taggagatac agttaagtta tctggtagtg acaagacgtt
    54601 taaactaact ggctttacgg atcatgccaa attcaatgtc tcaccagttc tctatacaac
    54661 catcaatgct taccaagaga tccgcttcga aaaagaagat acaagtgaaa atgcacggat
    54721 taacgcaata gttgtcagag gtaaaatcag taatttacct gaagatttag aacagatcaa
    54781 aatttctaaa ttcatcaatg aattacctgg atataatgcg caagtattga cttttggatt
    54841 tatgatcgga tttttgatcg ttattgcggc tattgtgatc gggattttca tttatgtact
    54901 gacgatgcaa aagattaata tctttggtgt aatgaaagca caagggatca caggaggatt
    54961 tattgcgcgt tctgtagtgg cacaaacatt cattttatca tttgttggta ttcttcttgg
    55021 tctattagga acagtgggaa catcccttgt tctacctgat gcggttccat tccaaagcaa
    55081 ttggctgttt tttggcgtca ttagcttgtt gatgctggta gtagctgtgt taggcgcact
    55141 attttctgtt cggacaatcg taaaaatcga tccgttgaag gcaattggat aagaaggagg
    55201 aagagcatga aagcaataga atttaaagaa gtagaaaaaa gtttccaaga tggcgaccaa
    55261 gtagttaaag cattgaaaga aacaaccatg agtatcgata aaggggaatt tgttgcaatc
    55321 atcggtcctt ctggttcagg taaaagtact tttttgactt tggcaggcgg attgcagacg
    55381 cctagcagtg gctctgtatt tatcaatgat caagaattca gtaatcaaaa agaaagtgaa
    55441 cgcgttaaac tacgttttaa agaaattggc tttattttgc aagcttccaa tctggttcct
    55501 tttctgacag taaaaaagca gttattatta gtagataaga tcaaacatga acatcgtcaa
    55561 aaagaagcaa aagaattatt tgagcagctt ggcgtggata agttgatcaa caagtatcca
    55621 gaagaactat ctggtggaga acggcaaagg gtcgcaatcg ctcgtgcatt gtacaatgat
    55681 ccgtccatta ttctagcaga tgaaccaact gctagtttgg attcagaaaa ggcacgagaa
    55741 gtagtcgata tcttggcaaa agaatcaaaa gacaaaaata aagcaacgat catggttact
    55801 cacgatacac ggctgattga caaatgcgat agaatattta tgatggaaga tggtgtattg
    55861 aaagaaaaag aataaccaaa aagcaggtgg aaaaatggtc catcgataca acaaagatac
    55921 acagcaaaaa attttgaaag aagcgactga cttgtttatg tccaagggat atctcggcac
    55981 ttcaacaaga gagatcgcac aaaaagttgg gatcacccaa cccaatctct atcattattt
    56041 cggtgataaa gaaaaactat atacggcagt tttagaaaac cacttaaaag atgttggaaa
    56101 agctttgaga gaaatcgttc aaacaagcga aacgggattt caagtaacct tgacaaaaat
    56161 ggcgcagttt ttgattgaga cacatctggt cgatttgttt ctgatgcttc acgatcttga
    56221 aagcaatctt tcaaaggaaa caagagatca tcttttcttt ctatggaaga aaaattatcg
    56281 tgaacctttt gaagaaatct tttcagcaaa ccaatctgtg ctaagaaatg ggatttcaaa
    56341 agaaatcgca gcaaggcatt ttttcttagt gttagcacct tacatcactc ggtcgaaaag
    56401 acctgtggaa gaaccgctaa atgtggcgca attgatcgat ttatatttga atggtgtatt
    56461 aggagaagcg taaagctgtt atatagggag aaaaatagtt aggtgaagaa gcaagatatg
    56521 acgaagatcg ttatatcttg ttttttttat ataggtagtt tttcataaat acaaatttgt
    56581 tattctctca tgattatcag ggtatatttt tatttattat gtcggtgttc caggaagtgt
    56641 tttaatttaa taacgaagaa attaattgtt tgtagaatga aggaaactat ttattgggta
    56701 gatgaatcac cacgaatagt caaaaggaga tttcaggata tgccaaaaat gaaaaaaatc
    56761 attttagcag taatgttatt ttctacggtt atatctttta cagccccttt tttgcgtact
    56821 taagctgatt ttaagttttg acccttagtc tggatctacg aggtgagagt caagaatgaa
    56881 aaaaataatt ggagcttttg tatttgcaat cattatcatt attatctgtt ttcaaataga
    56941 tgtttttggt caaaaaaaga tagttggaca aacggtcagc agtacgaaca gtacggttac
    57001 aaagacaaag gaatcatttg atgatacaga acaagagaca ttaatcaaaa tcggaaaaaa
    57061 tgaccgtaca ctatatacag atgactcgct aactacccca cttgcaacta taaacggcgg
    57121 agagctggcg gagtttcttt ctgaaacaaa aaatgcttat cagatcaaga caaatgatgg
    57181 ctatactgga tatttagccc tcgaagatgg aaccaaagtc acaaagaata tacaaacaaa
    57241 accggaagag ctatctgatg cagtgattgt attagatcct gggcatggcg gaaatgatac
    57301 tggggcatta agcaatgatg aacaaacaga agaaaaagat ataacattaa gtacagccat
    57361 aaaagtaaaa aaggcgctag aggatgctgg agcaacggtt tatttgaccc atactacaga
    57421 tgaattagta cagcttggag atatatgcga ctacagtgaa gaaaaaaagg cagatgtctt
    57481 tatcagttta cacgcagact ctacggaata tgcgaatgaa gcaactggaa tcacgacata
    57541 ttattactat ggacaagagg aaacattagc acagacaatt gctgactcct tcactgatct
    57601 gcctctggat tcaagaggaa tctccactgg gaactatcaa gttcttcgag aaaatcttca
    57661 accttctatt ttaatcgaga tgggttatat gaataatgat agtgatttaa aggaattagt
    57721 aacagacagt tatcagcagc agattgctgc aagtttgaca caagcattga ccacttattt
    57781 tcagtaataa ataagcccag ccaaacaaaa atagctcctc atatttttcg tttggccggg
    57841 cttattatcg cagatgcaag cttttgaaca ccgtttaagg aagaggttgt gagcctgccg
    57901 tttaactccg cgtcacaagg agcaatttca aaaaacagct tctcatgttt gatgactatt
    57961 gtgacttgtg accgaggagt tggcatgaga acaccgttta ttcggaacaa gggactgtga
    58021 catgactttt gtcacagttc cattattttt ttagcagctt caaagctttt tctgtattgg
    58081 caaaatgaag tttggcatat ttttcaagca taggcatgcc gcctttctcc aatagttttg
    58141 ccgctacttg gtcagatttc gttccagctc ctgatggaag ggtgattcca gcttcagctg
    58201 atgctttgtg taactcttcc aaaaagctgg cacgactgat gatagaagca gcagcaacag
    58261 ctaaatgata ttgttctcct ttagtaacga agtacagttt ttcttgtaat tgattttttt
    58321 ctaaacgcgc atatttttta aaatttgctt ccggcgtaaa ctgatcgatc aaaatcgctt
    58381 ctggtttttc tggctcgatt ttttttagca gcaaatggat cgcttgattg tgcaaagcga
    58441 ctttcatccg aacggcattg tattttggtt ggatctcatt gtatttttct ggagataaga
    58501 caagcagttt ataggggatg gtttttttta agatgtcagc aagctggatg atttggctat
    58561 cttttaactc ttttgaatct ctaacaccaa gtttacgtaa ttctgcaagc tgatcacgtt
    58621 tcacataagc agcacatact gttagcggac caaaatagct gccatttccg acctcatcac
    58681 tacctaaaac ggataattga ctgatatttt ttggcaaaga agaggctgtt tttgctggct
    58741 tggcttgttt atcctgtgcc tccccccatt tatcagcttc tattgctgca ttcgtacctt
    58801 gaaacatcac ttttccggat gtataagcgg taatggtcgt cccgtctttt tttgcagcaa
    58861 agctagtata aggaatctgt ttatttaaca aataagagcg atagtatgct ttcatttgac
    58921 taagttggtc gtttgttgct ttgataatga cgttgctcat aaaattctcc tcgtttttat
    58981 acataaaact ataccgcaac tcacgacttt tcgttttcta agagattgcg agacatagca
    59041 tttttttaaa gtttatcata taatagttaa gtatgtgaaa aatatttgtg gagaacggtg
    59101 aaagaaccaa cttcatggta cactaaataa aactttcatc aaataggagg aaatgattcg
    59161 tatggcgcac gaaaaaacac gctacaaagc agtgattgcc aaccaaacat atactattat
    59221 cggacgggaa accaagcatc atatggatat cgtaacgaag ctgatcaatg aacagttagc
    59281 agaattgaaa caattatcac cacaaatgga taatgaacaa gcagcaatct tgatggctgt
    59341 caatgcgctt tcggatcaat tgaagaaaca agaaagaatc ttggagctgg aagaagaaac
    59401 agcagaatta aagaaaaaaa tgatcaaatt tacagagctt gaaaatcgtg tgaaacgcat
    59461 tgaagcaatc gagaacgaag ctcgggaagt attgaaagaa aatggtcaag cagatcatac
    59521 cattaaaaat catgtggaag cacaacagat tttaaacgag aaacgaaaag gacaaattaa
    59581 acaaaaatct tctaattaag atccttttat caaaataaga aaaatttaaa aaagttagaa
    59641 gagaaaggaa cgtagcatgc tgagtttgct gattttattt ttattgctaa ttgcgttttt
    59701 ttctggagca cgtcgcgggt ttgctttgca aatcatattc gcgattggat atgtattgtc
    59761 atttattgct gcccagcatt tttacaaacc attagcaagt catttggaat tatacattcc
    59821 atacccagct gtcaccccaa catcaaagtt agcatttttt gatcaggtat ttgcttttca
    59881 cctagatgaa gctttttatg caggaactgc ttttctgatt attttgctaa ttggctggct
    59941 gcttacccga tttgtggggg tttttgtcca tggattgacg tatgtgccga tcttgagaca
    60001 ggtagactgg attgcaggag gcatcctgtc actaatcatg gcttacgtta ctatattttt
    60061 gattttgcag ttacttgcct ttgttccatt agatgtggtc caaaatcaat tcggcgagca
    60121 tagtttcgct cgttttatcg ttgagagaac gccatttctt accaacaaga tgtatgagct
    60181 ttgggtaacg aatattttga attaaggaaa atagtgctgg aaaatatttc gttttttgta
    60241 cagagtagtt tatttaagaa ggctgcgtag cgtatgtccg gcacagctct tttttcatag
    60301 tgaaagataa ggtgataaaa tgaataaccg aatccttgaa acattggaat ttgaaaaagt
    60361 caaacagatg gtcagacaat ttgtagtgac tgcacaagga aaagaagaac tggcagaatt
    60421 ggtaccagtg agtgagaaac aaacgatcac aaactggctt caagaaactg aggatggatt
    60481 gaaagtgcaa cgtctgcgag gcgggatccc tatacctaaa cttgaaaata tccgtcccca
    60541 tatgaaacgg atcgagatcg gagcagactt gaatggagtg gagcttgcac aagtttccag
    60601 agtattgtct acgacaagcg aattgaatcg tttcattgat gatctttctg acagtgaaat
    60661 cgaatttgca cgtttgtata tgtgggcaga tcagttagtc acgatccctg ttttgagccg
    60721 ccgtttaaag gaagcaatcg atgaagacgg acgcgtgact gatgacgctt ctcctgagtt
    60781 aaagagcata agacagaaca ttcggcgaag tgaacaagct gttcgtgaac agttagatgg
    60841 gatcgtccgt gggaaaaatg caaagtattt aagtgatgcg atcatcacca tgcgaaatga
    60901 ccgctacgtt atcccagtca aacaagaata ccgcggtgta tttggcggtg tagtccacga
    60961 tcaaagtgct tcaggacaga ctttatttat tgaaccaaaa caagtggtgg atttgaataa
    61021 tcgtttgcgt caataccaaa tcgctgaacg aaatgagatt caacgtattt taagtgaact
    61081 ttctgctgaa cttgttcccc atcgtcaaga aatcatccac aatgcttatg tgattggtaa
    61141 aatggatctg atgaatgcaa aagcacgatt tggtaaagaa gtaaaagcca tcgtgccggg
    61201 aatcagtgaa gacaatcatg tcgtcttgaa acaagcaaga catccactga tcgatcagga
    61261 aaaagtagtt tctaatgaca tcacaatcgg aaaagactat caagccatcg tcattacagg
    61321 acctaacaca ggtgggaaaa cgatcacgtt gaagacttta ggtctgttac aactgatggg
    61381 gcaagcagga ttaccgattc ctgcaggtga agaaagtcaa atcggtattt ttgaggaagt
    61441 atttgcggat ataggagacg aacagtcgat tgagcaaagt ctatcgacct tttcttctca
    61501 tatgacgaac actgtagata ttttatcaaa agtcaatgaa aaaagtctgg tattatttga
    61561 cgagctcggt gcaggaacag atccgcaaga aggtgctgct ctagcaatcg caatcttaga
    61621 tgatcttggt aaaaagtctg cttatgtgat ggcaacaacg cattatcctg aattgaaagt
    61681 ttatggatac aatcgggcaa atacgattaa tgccagcatg gagttcgatg tggatacact
    61741 aagtccaacg tatcgtttgc tgattggcgt tcctggacga agcaatgcgt ttgaaatctc
    61801 tagccgatta ggtcttgata cagaagttat tgatgaagcg aagcagttga tgaatgatga
    61861 gagccaagat ttaaacgaaa tgatcacaga tttagagaat cgccggaaaa tggcagagac
    61921 cgaatatctg gaaatgcgtc attttgtttc tgaggcacaa gaacttcacg atgatttgaa
    61981 agaagcttac agctatttct ttgaagaacg tgaaaaagaa atggaaaaag caaagaaaaa
    62041 agcaaacgaa gtcgtgtcag aggcggaaga aaaagcagaa aaaatcattg ctgatattcg
    62101 taaaatgcaa cagcagattg ggcaaggaaa tgtgaaagag catcagttga tcgatgcaaa
    62161 gacccaatta gcaaatctac atcaagaaga aactttgaag aaaaataaag tattgaagaa
    62221 ggcgaaagaa caaaaaacgt tgaaaccggg agacgaagtg ttggttacga cttacggcca
    62281 aagagggacg cttttacgta aaaacgggaa tcagtggcaa gtagaaatcg gtatattaaa
    62341 aatgaatgtg tccgaagacg agctgacgcc tgttgctcct caaaaagagc cgacacaacg
    62401 agttatccat gctgtacgat ctgaatctag tagtcacgtg ccgaatcaat tggaccttcg
    62461 aggaaaacga tacgaagaag cgctaagtga ggtagatcaa tatttggatt ctgccattct
    62521 agctggttat cctcaagtga ctattgtcca cggaaaagga acaggcgcac ttcgcaaggg
    62581 aattactgat tatcttaaaa accatcggag cgtcaaaagc tttgagtttg caccggcaaa
    62641 ccaaggcgga aatggtgcga caattgttaa atttaagtaa agcttactaa aggtaagcag
    62701 atggttcgct atccaagtat agaaatgcta tactaatcat agattttaaa aatggaggtc
    62761 tttgatatgt cacaagtaat tacagataag acatttaatg aagaaacaga taaaggactt
    62821 gtattgattg atttttgggc aacttggtgt ggtccatgtc gtatgcaagc accgattttg
    62881 gatcagttgg aacaagaata tgatgaagaa gaattcagaa ttgctaaaat ggatgtggat
    62941 gaaaatccag aaactcctca acaattcggt atcatgagca ttccaacatt aatgttgaaa
    63001 aaagatggtc aagtagtaga aaaagctgtt ggtgttcatt caaaagaaca actacgtcaa
    63061 atgatcgatc aatatttata aaaacttaca gcaaaaataa gctgagggtg ggactgaatc
    63121 cagttccgtc ctcggttttt ttgcggttga gttaaggtta ttcaaattaa tattttttga
    63181 gtataattac gttgtcaggc tggattgttt ttttgacaga catgctataa taactttaat
    63241 tgaatatgaa ggggagtacc agatgaacga acgaatcaaa aacaaattag ctttacttcc
    63301 tgatcagccc ggctgttact tgatgaaaga taaaaatgga acgatcattt atgtcggcaa
    63361 agccaaaata ttaaaaaatc gtgtccgctc atattttact ggcagccata atacgaaaac
    63421 ggaacggctt gttagtgaaa tcgaagactt tgaatacatc gttacagaat cgaatatcga
    63481 agcattgctc ttagagatca atctgataaa gaaaaatgat cctaaataca acattatgtt
    63541 aaaggatgat aaaacctatc ctttccttaa gataacgaat gaaaaatatc cccgtttggt
    63601 gattactcgt aaagtactaa aagacaaagc actgtatttt ggaccatatc ccgatgtcgg
    63661 tgcggcgaat gagacaaaga agatcctcga tcgattattt cctctgagaa aatgcaaacc
    63721 tagtcagacg aaggagcctt gtctttacta tcatttggga caatgtctgt gtccttatta
    63781 tttcgacgta gatccgaaag tctatacgaa aatcgttgat gaagtgaaaa agtttttaaa
    63841 cggaggacac gaaaaaatcg agtcagagat ccatcagaaa atggaaaaag ctgctgaaaa
    63901 catggagttt gaaaaagctg cagaataccg agaccagatc cgtgccattg agacaatcat
    63961 gactcgccaa aaaatgacaa atactgattt actggatcga gatgtatttg gttatgcgat
    64021 tgacaaagga tggatgtgtg tccaagtgtt tttcgtaaga caaggaaagc taattgaacg
    64081 agatgtttca atgtttcctt tctataacga agcagaagaa gatttcttga cttacctcgg
    64141 tcagttttat caggaaaatg agcatttcat tcctaaagaa gtcttgattc ctgatacgat
    64201 cgacaagccc agtgtagaag ctttgttagc tacgaaagtg ctgcaaccaa aacgaggaga
    64261 aaagaaaaaa ttagttgaat tggcgaataa gaatgcctca gttgctttga atgaacggtt
    64321 tgatctgatt gccagaaaac aggaacggac gatcggagca gttgaacgtt taggaaacgc
    64381 gatgaatatc ccgaccccaa tacgtatcga gtcttttgat aactctaata tcatggggac
    64441 gaatcctgtg gctgcgatgg tcgtattcat tgatggaaaa ccggcaagaa aagaatatcg
    64501 gaaatataaa ataaaaacag tcaacggacc ggatgattat gcatcaatga gagaagtcat
    64561 ctatcgcaga tattcacgag tgattcgcga agggttgcct ttacctgatt tgatcttgat
    64621 cgatggagga aaaggacaag tagatgtggc aaaagatgtc ttagaaaatc aattaggaat
    64681 cgatattcct attgctggca tggcaaaaaa cgataaacat aaaacaaatg agttgctatt
    64741 cggtatagat ttggctgtag taccgcttga gcgaaattca ccagagtttt tcttactcca
    64801 gcgaatccaa gatgaagtcc atcgattcgc aatcactttc catcggcagc tacgcagtaa
    64861 aaacagtttt gcttcccgat tagatgaaat tgaagggtta ggaccaaaac gaaaaaaaat
    64921 gctgcttaaa gagttcaaat cgttgaaaaa tatcacagca gccacgacag aagaattaca
    64981 agaaatcgga ctgccgaaaa atgtcgcaca aaacgtattt gataaattac atcaggaatg
    65041 aggaaagggc actttacaaa gaaagtaaag tgtcctatca ttttatgtac aacaaaaaga
    65101 gcgtttacgt tttgttggta aataataaat cgcttacgtc tggtgtctaa ggatatatgt
    65161 gatttcttga agaaggagtg aagaaatgtt agaagtcaag gatcttgtta aaacttttgg
    65221 gaactacaca gctgtcgatc atgtctcttt ccaaatcccc gatggaaaaa tcatggggct
    65281 aattggccaa aacggggctg ggaagacaac gacttttcgt ttgatcttgg attttttgac
    65341 acaagaccaa ggagaagtgt tatggaatgg ccatcatctt ggggagaaag attatgatgt
    65401 catcggttat cttccggagg aacggggact ttatccgaaa gtaacgattc aagaccaact
    65461 gctttatttt gcagaactta gagggaaatc aagaaaagag attgaaccaa aaatcgattt
    65521 ttggatggaa aaatttcagg taaaagggaa aaagacggat aaagtaaaat ctttgtctaa
    65581 aggaaatcag caaaaagtcc agctgatcgc cacgttaatc catgaaccta aattgatcat
    65641 tttggatgag ccattcagcg ggttagatcc ggtaaatgct gaattgctaa aagatggaat
    65701 attggaattg aaaaaacatg gttcatgtgt cattttttct agccacaata tggataatgt
    65761 agaaaaaatc tgcgatcatt tgatcatgtt gcgaaacgga aaaatggttt tgaatggaaa
    65821 agtacatgag attcgtgaat catttggccg tacgaagtta ttcttggaat ctggtttaag
    65881 ccaacaggaa gtagaagaaa tcgaaggcgt gaaaaaagtg atccttcatg aagacaatac
    65941 gttagagatt accttagaag atcctgaagc tgggaaagaa atctttactc gtgcgactca
    66001 gttcggctac attcctatgt ttaaccagca accgccaact ttggaagaga ttttcaaatt
    66061 gaaagcaggt gaaatcgatg cgtaagtttt ggattattac caaagatgtc tatttaaaaa
    66121 atgttaagtc gatttctttc ttgatcatga tattagtccc ttttatcatg ctgggtatca
    66181 tttatgtagc aggaaacttt gctcaacaaa atagtgatgt caataaaatc ggcgtattgg
    66241 ctgataatga gcaaatcagt cagcaaatga gccaagtcaa aacagatgat tttgagttca
    66301 aagcagttga ttctgaagaa aaagcacaaa aagagctttc ggaagaaaaa atcgatgcgt
    66361 atttagtagt ctcaactgag aatgataaga taaatgggat gctttatagc gaaaattcat
    66421 taggacaaag tacacaacta ctgatacaac aacaactgac tggcttgcaa tcgatgcttc
    66481 gagcaagtca attaggcatt tcaccagaag aagtagctag cttgagccaa caagcaagtt
    66541 tgactcgaca aaaagtcaat tttgattcaa aaggaaaaat gacagttgga gaagataact
    66601 cgacagtcca atatgtcgta agttatgtag caacgattgt cttgttcatt attattttga
    66661 cgtatgcgca gatcattgca caagagatcg cttctgaaaa aggcacgcgg atcatggaag
    66721 tgatcctgtc cagtacgact gcacaaaagc atttttacgg aaaactaaca ggtgttttac
    66781 ttgttgcatt aacgcaaatg gcattatacg gtattatttt tggtatagga tacagtcaat
    66841 tcaaagatat ggaaatggtc aaaaatatat tagacggtat ctcattggat aacttgattg
    66901 gaccattctt gtggtgttct cttctattca tgatctttgg cattttgatt ttttctgttt
    66961 tagcagcttt atgtggctct ttggtcaaca aagcagaaga tacagcaaaa gcaattttgc
    67021 cagtgactta tctatctcta ggcggatata tgcttggatt gatactagga gcttcagatc
    67081 caaacaatat cgttattcgg atcacttcgt atattccatt cttatcttca tatattatgc
    67141 cggttcgctt agcaaatgag acagtcggta tgggtggagc attgatttcc ttgttggtac
    67201 ttgtagccgt aacattctta ttgatgatct tgtctgcaaa catgtacaaa tcgaatgtac
    67261 tcgtgtatag cgaaggcgga ttatggagtt cattgaaaca atcgatttca attatgagaa
    67321 atgaacgaaa aaaagcataa aatatagaaa aatatagaag gaagctggac atttattgtt
    67381 cccagcttct tttttgtata gacctatttc tattttttta ttatattgga tatatattca
    67441 ttgaaaatag agcataacaa ctttataatg ttgagtatac caatttttgg aggcgtttta
    67501 atggaccgct atttagattt actttcagag aagttcccta caacggaaga tgtcatcacg
    67561 gaaatcatca atctcgaagc aattttgcag cttccaaaag gaacagagtt atttttgagc
    67621 gatatacatg gcgaatttcc tgcttttgat catattctgc gtatcggttc aggaaatctt
    67681 aaagaaaaga tcaaagacct tttctctgaa caaatgacgg aaacggagat cagccaattc
    67741 actattttta cggcttatcc agaatatgtg ttgacgactg attggtacaa aaaacaagat
    67801 aaatcccagc tgatccatcg tttgatcgat cttttacggt ttacgacagt caaatacact
    67861 cgatcaaaag ttcgaaaagg attgccgaaa gaatatagct atatcattga ggaactcttg
    67921 tatatcgatg atcgtatcaa cgggaaaaaa gactatgtaa aaaaaatcat tgaacaactt
    67981 gtcttgatga aggaagaaga aaaattttta acaaaacttg cgcagacgat ccaaaaatct
    68041 gtcatcgatc atttgcatat cgtgggtgat atttttgatc gaggaactca agcagccaaa
    68101 gtaatggatc gaatcatgga tttttcctct gtagatatcc agtgggggaa tcatgatatt
    68161 ttgtggattg gtgcgtattg cggctctgag gcatgtttat tgacgctttt acggattgcc
    68221 gcacgctaca actatttatt tgaattagag aaagaatatg gattaaattt acgtccatta
    68281 ttttcttttg cccatcaaac ctatcagaag aatccagtat ttacccctaa aaacaggaaa
    68341 gatctatctg aaagagagca agaagaatta gaaaagatcc atcaagcact ttctatcctc
    68401 caattcaaat cagaacatca gttgttgaat cgacgacctg aatttaaaat ggacgatcgt
    68461 aaattgttgg aaaaaatcaa ctatgaggaa tcaacgatcg ttttagaagg tcagctctat
    68521 gagttgaaag ggacttgttt tcaaacgatc cagccagatg atcctaaaaa attcttggaa
    68581 gaggaacaaa aagtgatcga tagtttgatg tattcattcc agcactcgtt aagaatgcaa
    68641 aaacacatga cgtttttgat cgaaaaaggg ggaatgtatc tcacgaacaa tcagcatgta
    68701 ctgttccatg gctgtatacc tgtagatgaa aaggggcagc tcttagcatt tgaattagac
    68761 caatcttatc gcggaaaaga actgctggga ttttttgaaa aacagataac tgaaagcgca
    68821 aaagatttga ctgcaaatga agatttggcg accgatttga tttggtatgc gtggagcggg
    68881 ccattttcgc ctttattcgg caagagtaaa atggcaactt ttgagcgcta ttttctcaca
    68941 gagcctcata cgcacgtcga aaaaagcaat ccctattatc acttgcgaga tgaagagtgg
    69001 ttcagtgaaa aaattttggc agaattcgat gcaaaagaag aaggttcagc aatcatcaat
    69061 ggacacacgc cagtaaaagt aaaaaaagga gagtcaccga tcaaagcaaa cggaaaagca
    69121 tttgttattg acggaggtct atccaaagct tatcaaaaaa caaccgggat tgctggctac
    69181 tcattactat gcaattctta cggtttccaa atcgtgacac attatccgtt cttgcctatt
    69241 gaacaacaat ttgcaaaaaa atctgatcaa acgaatgtaa aaaaagtgat cgagcagcag
    69301 ctcccacgca aacttaatcg gaatacgaca aaaggaatgg aattacagca acagattact
    69361 caactccaaa ggctgttgga ttatcgaaag gacgattgag aaaaatgcta gccaacattg
    69421 ctcaatagac taaaaagcga ctgcaacaaa aggcgtgtcg cagtctcctt cggaattagc
    69481 tcaaaaaacg gtaaaatatt agaagctatt tttctgttta tttctctaat actcaggtca
    69541 gggcgctgat ttcacgacct cttccttaaa cggtgttctc ctgccaactc ctcggtcaca
    69601 agtcacaata tccaacaaac atgagaagct gttttttgaa attgctcctt gtgactcaga
    69661 gttgaacggc aggctcacga cctaatcaga aaaacgatta aaattcattc acaaagaaat
    69721 cgaataaacg ctgttcagat gaatctacac gatgagaaag ttccggatgc cattggacac
    69781 caaggatttt gtgcatatta tctttacttt ggactgcttc aatgagtcca tcgttggaaa
    69841 aggcgatggc ttttaacaaa ggagaaagat ctttgactgc ctgatgatga taggaattca
    69901 caaagtatga atcagggaga aggtcactta ataaactgtc cgaaacgatt ttgacttcgt
    69961 gagttgcaaa ctgcggggca gtgggctgtt gttcgtgttt tacggaccat tttggatata
    70021 atgaaagatc ttgataaagt gttccctcca acacgacatt caatagttga agtcctcggc
    70081 agactgcaaa aatcggtttt ctttgtttca atgcttccaa gatcaatgcc tgttcgaatt
    70141 ggtctcgttg aatatttgtt tccgtcagtt ttggatgagg gtcttccatg taaagttgcg
    70201 gactaacatc ctgaccgcct gcaagaatga gtttgtcgat tttctcaatt agttgaggcg
    70261 ctgaatctgg agacatgact ggcagaataa gaggtaatcc ttgagcatct aaaactgcat
    70321 ccacaaatcc ctgcggtgta tagcttactt gatttccttg gaaagtatct gtcgctcgaa
    70381 tcagttgatt cccggcaatg ccgatgattg gtttcatttt tattccccct aaagtagact
    70441 aattgtaaca aggatttaaa aaaatttaaa ctatgtaaga cttgccccta tacttatctg
    70501 ttcttgctgt gttactatct gtaaagagaa ttttcgtgtg aaattcatga cgatagttga
    70561 aaatattgct taatttgtta taataaaaag taagcagaaa taaaaaggtt gggcgtaagc
    70621 ttcaaggatc tagttcttca aggggtgaga aggacatttt attgaagggg cctgcctata
    70681 ctaagttatc tttagaggta catactttca atgaaaaaag aaagcatgta cctctttttt
    70741 aaatcgaaag gaagtgaagc aagtgttaga agctttggaa caaatccgaa aagcagaaga
    70801 agaaaatgag aagcgtgctc gaaccctacg gcagcagttg aagacctatg cagaagaaaa
    70861 agagcaagaa ttggagataa tccaaacgaa cagtcggcaa cagctgaaac agttggtaga
    70921 agaaaaagaa caattcgaaa agcaagaatt agaaaaagaa aaaatgaaat tgaaagcaga
    70981 agcagacaag gtgcaagcaa ctttgaaaga ccaatatcaa aagcatcaga gtcaagcaat
    71041 cggtgcaatc attgaaaggg tgaaagaaac ttatggccgt cactaagatg gaaaaagtga
    71101 ccctcatttc agataaaaga aatcaggaga ggattttaca agcagtacaa ggaatccaaa
    71161 atgttgaaat ccgggatctg tatcaaaata gaacaaacaa ccagtgggta gaaaaatatt
    71221 ttccagatac cacgattatt gataaagaag caaaattaag cgctttaggc aatcggctga
    71281 aagacatcca agaagctatc caattcatac aacaccacgg cgatagccgt caaaagaaac
    71341 tccatttgaa acgtcaagaa ctttccttac aagacttgga agcaaattat tccgaagaaa
    71401 atttcatgaa taaattagaa gaggtccttg atttaaaaga aaagtgggaa cagctaactg
    71461 aaaaacgtga tcgtttagaa gaagaggaag aatggcttct tcattggcaa cagctggata
    71521 ttgctccaag tatgtatgca agtaagacga ccatttttga gatggggact gtgagtgcag
    71581 caaattttga aagtttcaag gaagaactaa gtaagcttga tgacgtttat atggaagaaa
    71641 tagattatac gccaaaacaa gtttatcttt cgtatgttgc tttaaaaaaa tcagttgctg
    71701 ctatagaaga aattgctggg aaatacgggt tcaataaaga aacgtatcct tatgaacaaa
    71761 atcctaaaga aaaattgcaa gaaaccaaac agcaattatc cattgttcac gagcagcaaa
    71821 aaaagataac gacagcgtta ggtcagtgca gcggctatat ccaagaattt gaatgggtag
    71881 aagaagtcac acttgccgtt gcagaacggg aaaaagtaaa agaacggttt atccatgcca
    71941 cttatctgat cgttttgcaa ggttgggtag atgcagaaga aaaacagaat ttgatgcatg
    72001 tgttaaacga aactgtatca gaagaagata tatacgttag tttcgaaaca ccaaactcag
    72061 aagagattca gcaggaagtc cctactaaat tgaaaaacca tccgcttatc gaaccttttg
    72121 aattgctgac tgaaatgtac agtctgccaa aatatgaaga agtagatcca acgccttgga
    72181 tgacaccatt ttatcttgtc ttcttcggga tgatggtcgc agatgttggt tacggattgc
    72241 tgatgctcat tgggacaata ctagctcaaa aactatttgt tttaccccgc gggatgaaac
    72301 gtttcgtaaa attctttgag attctctcgg taccatcgat catctgggga ttgatctaca
    72361 gttcattttt cggacaggca ttaccaaaag aactatttgg tatccgcttg cctttcccaa
    72421 tcctatctac gacggatgac gtcaatacga ttttgatttt atccgtgatt ttcggtctga
    72481 tacagatctt ggttggatta ttcgtggcag caaaggaaaa tatcaggagg aaagattact
    72541 tgagtgctgt cagtgatggt tttgcctggc aagggatcct gattgggatc gttattgcat
    72601 tgattggtgt catgttgata aaaaatacag catttgttta tcttggcgcg gggctatcga
    72661 tcattgctgc tttatgtatc ttaatcgtgc cgattatcca atcgccgtct aaagtcaagg
    72721 gtgctgccaa aggagcgtat aatctttacg gattgactgg ttatatcggt gatttagtca
    72781 gttatacacg tttgatggca ctaggtattt caggcggaag tattggcgcg gcattcaata
    72841 tgctagttgc tttcatgccg ccagccgctc gattcagtgt agggatcctt ttgatcatcg
    72901 ctttacacgc actgaatatg tttttgacac tgttaagtgc ctatgtccat ggtgcacgat
    72961 tgcagtatgt cgaatttttt ggaaaatttt atacaggagg cggacgtgcc tttgacccgc
    73021 tgaaaacggc ggaaaaatac gtcaacatca atcataagaa aaaaaacaat aaataattgg
    73081 aggattttta tacaatgatg gattacttaa ttagtcaaaa tggtggaatg gtatttgcag
    73141 tattagcgat ggcaacagcg acgatttttt cagggattgg ttcagctaaa ggtgttggaa
    73201 tgacaggtga ggcagcagca gcgttaacaa caagtcaacc cgaaaaattc ggacaggctt
    73261 tgattctgca attgcttcca ggtacgcaag ggttgtatgg attcgttatc gcctttttga
    73321 tttttatcaa cttaggaaat gatatgtcag ttgtacaagg attgaacttt ctaggcgctt
    73381 ctctgccgat tgcttttaca ggtttgtttt caggtatcgc ccaagggaaa gttgcagcag
    73441 caggtatcca aattttagcg aaaaaacctg aacatgctac aaaaggaatc atttttgctg
    73501 cgatggttga aacatatgcg attttaggtt tcgttatttc cttcctatta gtattgaatg
    73561 cctaagcata aaggaggaaa agcagatgaa cgccattgaa aaaatcatct ctcagatgaa
    73621 tgaagcagca gagcaagaaa gagcggcgtt agagcaagaa gagcgaatga agatcgatca
    73681 aaactttgaa caaaaacgta cgcaaatcga aacagaacat caaaaacaaa aagaaaaaca
    73741 aatcgaatta cttgaaaaaa aataccgtca gcttaggaat cgccaacaag tagaagtacg
    73801 acaagaaaat ttgaatgcga agcaggaatt tttacgacga ttgtttgcag atgcaatagc
    73861 tgaaatggag aattgggatg aatctgaaca aatccagttt atcaaaaatt cattgtattc
    73921 attacctttg acaggcaaag taacattcat tgctggagaa aaatcagcag cttatctttc
    73981 tcagacattg ctggatgaat ggaacaatga acttcccttt atgatggttt taagtgatga
    74041 aactgttgct gatcaagcgg gttttctgat aaacgatcaa ggagttcagt ataattttct
    74101 tttcagcagc cttgtacaag atatccaagg aacgatgagt tttgagattg ccaatcaatt
    74161 attcgaataa ggagggatca gtgtatggaa taccacgaac taaatccctt gattcgcgga
    74221 agagagcttg aacttttgtc caatgagaca tttgaacgga tgattcaaac aaattctgtc
    74281 gaagcacttg gtgaaatatt gaaatccacg atttacagtc catatattta tgacggatat
    74341 gaatatgact tcgaacagaa tcttttaaag gagcagagcc gtctatttcg ctggttaaag
    74401 gaatcagcac cggagcctga aatcgtttgg atctatacga tgcgctatac tttccataat
    74461 ctgaaggttt tgacaaaagc cgagatgaca aatcaaaatc tggaccattt gtatatcgac
    74521 gatggatttt attcattaga aaccttgaag gatgccattc atacgcaagt ttcaaatgaa
    74581 ctccctgaaa gcattatgga cagtatacga gaagtacgtg attattttga agagtctacc
    74641 attcttcagg gaattgacgt gatttatgat cgacagtttt tgacagagca gcgacggctt
    74701 gccgataagc taggatatca agaattgctg acagaagtca ttgcttttat tgacttgacc
    74761 aatatcacaa cgatggctcg aggaatattg cagaaaagaa catatgggtt catgacgacg
    74821 gtactttcca gctcgggaag tatcgaaaaa gaagtatttt tgaactttgt agataaagat
    74881 atggaagatt acacgaattt tctattagag acagattatg ctgattttct gcgccctgtc
    74941 atccgtgagg gaaatcttga tctcgtaaag cttgaacagt tgaaagatga ttatctaagt
    75001 tcattgtatc aagaagcaca aacccaggct ttcggaccac tgccactact agcctttttg
    75061 aacgcaaaag aggtagaaag caaaaacctt cgtttactgg ttatcggcaa aagaagccat
    75121 ttcgaaccag aaacaatcag aaagcgggtg agacaagtct atgacgcata agatcggtgt
    75181 agttggcgac aaagattctg ttttgccatt caaattgttt ggctttgatg ttcgttatgg
    75241 tacaaccaag caaaccgttc gtcaggcaat tgaagaaatg gcaaagaatg agtatggcgt
    75301 gatttatgtc acagagcaat gtgcagcatt gagcccagaa acgatcgaac gttacaagga
    75361 acaaatgata cctgctatcg tattgattcc caatcatcaa ggatcattag ggatagggct
    75421 ggaagaaatt caaaaaaacg tagaaaaagc agtaggtcaa aatatcttat agtatgaaaa
    75481 ggagatagaa attttgcaaa ttggaaaaat cataaaagtc tccggacctc ttgtaatggc
    75541 tgagaacatg tctgatgcca gtatccaaga catgtgtcta gtgggagatc taggagttat
    75601 cggagaaatt atcgagatgc gtggcgatgt ggcgtctatt caagtatatg aagagacttc
    75661 tggaattggt ccaggcgaac cggttcgctc tactggtgaa gctttatctg ttgaattagg
    75721 accagggatc atttcacaaa tgtttgacgg aatccaacgg ccattagata cctttatgga
    75781 aatcacacaa agtaatttct tagggcgcgg agttcaattg cccgcattgg accatgagaa
    75841 aaaatggtgg ttcgaaccaa cagtagaagc cggagaaacg gtgagtgctg gagatgttat
    75901 cgggatcgta gaagaaacaa aagttataaa acataaaatc atggtgccaa atgggataaa
    75961 aggtacgatc aaaacaatcg aaaaaggttc attcactatt gatgaaacag tatgtgtcat
    76021 tgaaaccgaa aatggtgaca aaaatttgac gatgcttcaa aaatggccag taagacgtag
    76081 tcggccaatc aaagaaaaat taaacccgga tgcacccatg atcactggac agcgagtgat
    76141 tgatacattc ttcccagtga caaaaggagg agcagcagct gtacctggtc cttttggtgc
    76201 agggaaaaca gtcgttcagc atcaaattgc aaaatgggcc gatgtggaca tggttgtcta
    76261 tgtgggatgt ggcgagcgtg gaaatgagat gacggatgtt ttaaatgaat tccctgaatt
    76321 gattgaccct aatacaggag aatcgttgat ggaacgtacg gtattgattg ctaatacatc
    76381 aaacatgcca gtagcagctc gagaagcttc tatctatacg ggaatcacaa ttgcggaata
    76441 tttccgtgac atgggttatg acgttgctat catggcagac tccacttcac gatgggcaga
    76501 agcacttcgt gagatgagcg gacgtttgga agaaatgcct ggtgatgaag gttatccagc
    76561 ttatcttggt tcacggcttg cggaatacta tgaacgatct ggaagagtca ttgcattagg
    76621 atcagaaggt cgcgaaggaa gtataaccgc aatcagtgct gtatcgccgt ctggagggga
    76681 tatttcggaa ccagtcacac aaaatacatt gcgggtcgta aaagtattct ggggtcttga
    76741 ttccagttta gcccaaaaaa gacattttcc ttcgatcgat tggatacaaa gctattctct
    76801 ttattcaaca gaagtaggga agtatatgga tcatatcctt caagctgact gggcatccat
    76861 ggtcaccgag ggcatgcgta ttttgcagga agaacagcag ctgaatgaaa tcgtgcgttt
    76921 ggtagggatt gattcccttt cagataatga ccgtctgaca ttagaagtgg caaaatccat
    76981 tcgtgaagat tatttgcagc aaaatgcttt tgatgatgtc gatacattca cttcaagaga
    77041 gaaacaattc aaaatgttga agatgatctt gacctttggt gaagaaggac gccgtgcgtt
    77101 gtcgttaggt gcttatttaa gtgagatcat ggacggtacc gtatcgattc gtgaaaggat
    77161 cggacgaagc aaatatatcc cggaaacaga attagaaaaa ctagatcaaa ttattggtga
    77221 aatcaagcaa acgatgcaaa cgatcgtttc agaaggaggc atgagcaatg attaaagaat
    77281 atcgtacgat cggtgaagtc gtcggtccat tgatggcggt tgaaaaagtt gctggtgtca
    77341 aatatgaaga attaatcgaa gtccgtatgc aaaatggcga gattcgtcgt ggacaagtat
    77401 tggaagtcca agaagataaa gcaatggtcc aaatattcga aggaacaagt ggtatcaatt
    77461 tacgtgactc ttctgtacga tttttaggcc atcctttaga actaggtgta tcggaagaca
    77521 tgatcggtcg agtattcgat ggtttgggac gaccgaaaga taacggacca gagatcctgc
    77581 ctgaaaagca tttggatatt aacggagaag taatcaatcc agtagctcgg gattatccag
    77641 atgagtttat ccaaacaggt atctctgcaa tcgatcattt gaatacatta gttcgtgggc
    77701 aaaaattacc agtattttct ggctctggtc ttcctcataa agaattagct gctcagatcg
    77761 cgcgacaagc aacggtactc gattcatcag atgatttcgc cgtagtcttt gctgctattg
    77821 gaatcacttt tgaagaagca gaatttttca tggaagattt tcgtcaaacg ggcgcaatcg
    77881 accgttctgt catgtttatg aatttagcaa acgaccctgc aatcgagcgt atcgctactc
    77941 ctcgtatggc tttgactgct gcagaatatc ttgcttatga aaagggaatg catgttttgg
    78001 ttatcatgac agacatgacc aactatgcag aggcattgcg agagatttct gcagcacggc
    78061 gagaagttcc aggaagaaga ggatatcctg ggtatcttta cacgaactta gctactttat
    78121 tcgaacgagc aggaagaatc cgcggactaa aaggatcggt tactcaaatt ccgattctaa
    78181 caatgccaga agacgataaa actcatccaa tccctgactt gactggttat attacagaag
    78241 gacagatcat cttgactaga gagctttaca agagtgggat tcagccacca attgatgtac
    78301 tcccgtctct ttcgcggtta aaagataagg gaactggacc cggaaagaca agagaagacc
    78361 atgcagctac gatgaatcag ctttttgcag cctatgcaca aggaaaacag gcaaaagaat
    78421 tggccgtagt tttaggtgaa tctgctttat ctgatgtaga caagatctat gcgaagtttg
    78481 ctgagcggtt tgaaaaagaa tatgtcaatc aaggattcta cacgaaccgt tcgattactg
    78541 aaacacttga tctagggtgg gaactgctat cgatgttgcc aagaaccgaa ttaaaacgaa
    78601 tcaaagacga catgctggac aaatatctgc cagaagggaa gtgagttctg atggcacgat
    78661 tgaatgtgaa tccgacccgc atggaattga ctcgattgaa aaaacagttg acaactgcca
    78721 caagagggca taaattatta aaagataagc aagatgaact gatgcgtcaa ttcatcctgt
    78781 tgattcgaaa gaacaaccag ctgcgtcaag aaatggaaga gtctatgaca gaagcaatgt
    78841 ctgattttgt attggcaaat gcttcgatca cggagccttt catcgaagaa ttatttgttt
    78901 tgccggcgga aaacgttgat ttgtctatcg tagacaaaaa tatcatgagt gtaaaagtac
    78961 ctgtgatgaa ttttgaatat gatgaacagc tgacagacac acctttggaa tacgggtatt
    79021 tgaattccag tgccgaactg gatcggtcaa tcgatcggtt tactaccctg cttccaaaac
    79081 ttttggaact gacagaaatc gaaaaaactt gtcaactgat ggcgagtgaa atcgaaaaga
    79141 cacgtcggcg agtcaatgca ttagaatata tgacgatccc tcaattagaa gaaacgatct
    79201 attatattcg tatgaagctg gaagaaaacg agcgcgcaga agtaacaagg ttgatcaaag
    79261 taaaaaatat gggtaccact gactaagtgg tatccttttt taaaagagga aaacgatgat
    79321 taaacaaagc aaacaaataa agaaacgctt gccggctgtt cagcttctcg cattaggatt
    79381 ttttctcctg attttagttg gcggcggcct acttacccta ccatttttta gtaatagtgg
    79441 gcatgggaca aattttatcg atgcgctttt cactgcaact tctgctgtct gtgtgacggg
    79501 attgacaaca ttgaatacag cagagcattg gaacagtgct ggtcaatttt tgatcatgct
    79561 tttgattgag atcggcggtc ttggttttat gatggttccg attctatgct ttgcattgat
    79621 aaagaagaaa gtcagtctca gcacacgtat tatattaaaa gaagcgctga atctagaaga
    79681 agtatcaggt gtgatgaagc tcatgcttta catcctgaaa tttgcctttg tgatccaact
    79741 gattggtacg gttgctttat cttttgtatt cgtgcctgaa tttggctggt tgaaaggtat
    79801 ctggtacagt ttgttccatg caatctctag tttttgtaat gcagggtttg atttgttagg
    79861 agacagttta gccaatcacc agcaaaatgt ttatttgatc atggtggtat ctgctttgat
    79921 catttctggt gggttaggct tcatcgtatg gcgtgattta ctggaatatc atcagaaaaa
    79981 gaagataacg attcattcaa aaatcgcatt aaccgttaca ggtacccttt tattaggcgg
    80041 attcgttgtg ttctttttca cagagcgcaa tggggaaacg ctagtggaag ggaatatgtt
    80101 tcaacgattg gcaaacacct tttttatgag tgtgacacct agaacggctg gatattattc
    80161 agttgattac ctccatatga gccatgcagg tctgatttta acgatgtttt tgatgtacat
    80221 cggtggaaca tctgggtcga cggccggcgg attgaaaaca actacgttag gtgtgttgct
    80281 gatccagatg cgttcgatgc ttaaaggacg tacgagagcg gaagcatttg gccgtaccat
    80341 ccgacaaggc gcagtgttgc gggcacttac tttatttttt gttacgttga cgttgtgtgt
    80401 agtcgccatc atgattttat cggtgactga aacgatacct aaaacttctg gcatcgaata
    80461 tattgctttt gaggtcttct ctgcgtttgg tacagtaggt cttacgatgg gattgacgcc
    80521 agacttgact gcaataggga aattgatcat tatagcgctt atgtacattg gacgagttgg
    80581 tgtattgact gtggtcttct ctctgatgac aaaagcacaa agaacacaat caaaatacaa
    80641 atatccagaa gaaagtgtca tgattggata atttcatctt ctgacagaaa cctagtgatt
    80701 tagtaaaata agaaaataaa ataatttttc ttgcttcttg gatactttaa gtgcaaaatg
    80761 ttcgtttatt ttttgaggca ctatccgttg ttgaacctcg ggtagtgcct ctttcttatt
    80821 gaaaggaatc aataagattt gattccttta tttatcaata ggttataatt catatttttt
    80881 tattttttct tttacgatac ttagtccaga agctaaaatt tcaaggttat tagaggatag
    80941 ggaaattcga acgaatgcat ctggttgcgc acgtgtagta aagcgtctgg aatgataaag
    81001 tcggataccg ttagcaagaa agtcattctc aattatctta ggatcaatct caggatcaac
    81061 tggaagaatt cgatagtaag ggacacgatt cgttggtttt tctactttga aaagagaatc
    81121 aaaaagctga ttggctcttt tcgtaagact taatttagtt tctaagatcc tatttgcttc
    81181 atttgaatgg aggatttgag tgatgacttc cacatctaat ccagaagttt tcacatttat
    81241 attaaaaatt gcttgttcta tcttgttttg gacatgtact ggaactacaa gataagcaac
    81301 tcgcaatcca gaacaaataa attttgtcat tccagctaag tagattgttt ggttaggtaa
    81361 taatttttgg aaaggaggaa tgatcgtatg ttgatagtaa gttgttaaaa atgaatggat
    81421 atcatcttca ataacccata gaccttcttt ttcaatcact tcggctaatt gctctcgtct
    81481 tttgtgagag atttgaaacc ctataggatt attacaagaa ggcataagaa agacaccatg
    81541 aatcttcttt tttctacatt cctgaatcaa tatatcaggt cgcattcctt gctcgtcaaa
    81601 atcaattgga acgatctcta aatgatataa ctgagccaat tcaatgaaat tagcgtatgt
    81661 atatcggtct gttgctattc tatcacctgg agagaaaagt gcagaaagtg tgatagccaa
    81721 tccattttga acaccggaaa caatagatag agattctaag gacggaatga ctccttgagt
    81781 ttttaaccaa tttgctgcag tagtcaattg aaaatttgtg cctttgggat cttggtaatt
    81841 aagcaaacca acaagatttg ggttattact agttgattga ataaacggga caacgaattt
    81901 attacattct tcaaaagaac taaccagacc aaaatcaatg atatgttcgg ttacttcatt
    81961 ggtagagatg gtgatggact caaagacatt gggagaaata aatgtgccac ttccaatatt
    82021 cgtatacagc aaacctttct caattccata tttataagcc ttgccaacgg tagtaaaatt
    82081 taaatctaaa taatcagcta gctctctttg ggagggtaac tgagtgtttt tctgtaattt
    82141 attctttaaa atatcttgtt ctaattgttg aatcaacgat cgataataag gacgcttcaa
    82201 tttttgtttg tctggtcgcc aagttaacgg gtaattgtca taagaattaa taggcatttt
    82261 ctacactcct taaaattgta taccatacaa ttttaccatt gattgtattg attttagaag
    82321 ttaatctttt gtgaggaggg aattgtctat gaaaattatt aattttgagg aagtagtagc
    82381 ttcttttagt tttgaagaag cgattcaagt aatgaaaaaa tgtttttttg attatgaaag
    82441 tggtaaaatc agccaaaatc ctcgattggt ggaaatttta cctgacggaa aagacaaaaa
    82501 tatgtttgcg atgatgcctg cttatttggg ggagaacaga tattttggaa caaaagtcat
    82561 taccgctttt ccggataatc atcagtatca tttaccttct catttaggag agattttctt
    82621 gtttgatgct caaaacggac tacccaaagc attgataaac gcaaatgcag tcacctggat
    82681 tcgaacagct gctgtatctg cgctggcaac agattactta gcaaatccgc atgcagaaac
    82741 acttgcttta attggagctg gtcaacaagc attgtcgcat ttgactgcga tttctaccat
    82801 tcgtcccatc actacagtgt ttgtttacga tattttagaa gaaagacgaa atacttttat
    82861 cgctaaagct aaaaaacagt atcctaaaat aacgtttata aatgcaatat cagtagaaga
    82921 tgcagtacgt ccagcggaaa tcatttgtac gttgacctct agtaaagagg catttcttca
    82981 aaaagagtgg gtaagggaag acgcacatat caatgctgtg ggcacattta ctcctgatac
    83041 aagagagata agtacatcgt tgatggaaac ttctcaaatc tatgtagatg attactcagc
    83101 taccttaaca gaaagcgggg acctgcttat agccatggca gaaggagatt tagaggaatc
    83161 ttgtattgtt ggtacattag gcgaattagt ttctgagaaa aaaacatttt ataaaggaga
    83221 atcgaggccg acgattttcg acgcagttgg tctagctatt gaagatcttt gttgtgcaga
    83281 atatatttat aacaaattag agaaaggggc tttaaaatga acttagatta ttacgtagtt
    83341 gatgcatttg cagatgaggt gttcaaagga aatccagcag cggtttatgt gctagaagaa
    83401 tggctgccag aaggtacgat gcaaaaaatt gccattgaaa acaatttatc tgaaacagca
    83461 tttacagtga agaaaaacca agaatttgag cttagatggt ttacgccaga tcgagaaatc
    83521 gatctttgtg gtcacgcgac attagcaaca gcatttgttt tatttaacta ttacaaaata
    83581 cctgatgaaa cgattaaatt ttctactcaa agcggtaatc tatttgtgac aagaattaaa
    83641 gattattatt acatggattt tcctagtatt atgccgaaaa aagtgccgat attgactgaa
    83701 tatgaagaag caattggggc taagattaaa gaagcctact tagcacgtga tttatttttc
    83761 gtattagaag atgaaaaaac ggtggctaaa ttgcagccag attttacagc tatcaaaaat
    83821 tttgaattag gaatagagtc atcgtgacag cagaaagtgt gcaaaaagac tttgtttcta
    83881 gaaccttctt tccaaaatta acaatcaatg aagatccagt atgtggatca gcacattcta
    83941 atcttattcc ttattgggca gaaagaatga ataaaacaaa attgtcagct tatcaaatgt
    84001 catcaagggg cggggatcta gaatgtgaat taaaagaaga tcgtgtgata ataggaggaa
    84061 aagcagtttt gttttctaaa ggtacctcgt ttatttgatt tctttcaaat gaattaaaaa
    84121 taaattggtg gagagtggca gccttatagc tacaatggtt gttaaaaaaa gacgcaaact
    84181 ttttcaattt aatgaaaagt ttgcgtcttt ttttaattat tggtgtttgt tttttattca
    84241 atcaagagta aaatgcccca tactaactat cctcggatga cttcgatttt ataaccatca
    84301 gggtcaatga caaagtagta agaaggcgta gtgccaggta atccttttaa gtcagtaatc
    84361 tcaagacctg cagctttatg ttgctcgtgt aatttttcta aatcatcagc tgcaatagcg
    84421 atatgaccat agccgtctcc tagatcatac gcaccatgat catagttgta agtcaactct
    84481 aattcatagt catctccagg aagtgtcaaa taaacaagtg taaatttgtt ttctggaaaa
    84541 tcacggcggc ggctttcttc aaaaccaaat gccttttgat aaaattcgat tgatgcttca
    84601 agatctttca cccgaacaca tgtgtgagcc attttcataa attcatctct ccttttcctt
    84661 ttactcaatc ataacaaaaa gaagtaagaa aatagttgat ttgtgcttgt tcatgagaaa
    84721 tttctcatgt aaaatggata gaaaataata ctgttaaggt ggaaacaatt catggataaa
    84781 ccaatttttg gtgaaaaaaa gcaatctgct aattatcaaa cccgttatgc agcatatatt
    84841 gtcatagaaa gagacaagcg gattgcggtg atcgaggctc caaatggtgc ttttttcctt
    84901 cctggtgggg aaatcgaagg agaagagacg aaagaagaag cgattgtccg tgagctgata
    84961 gaagaaatgg gaattgtggc agaaatttct tcttatctgg gagaagctga tgagtatttt
    85021 tactcgaatt atcgtgcaac ttattattat aatccaggat atttctttgt tgctgattct
    85081 tggaagcgta taggagaacc aactgaaaag accaataaaa tttggtgggt gagccctcaa
    85141 gaagcgcttg tgaaattgaa acgtggtagc caccgatggg cagtcgagag atggatcgaa
    85201 aaaaataaaa actgaaagaa agcgagtaga tcagctttct ctcagttttt ttatttatta
    85261 cagtacatat tttttgattg cttcagctac accgtgctcg tcgtttgatg aagtgatgac
    85321 atttgctgct tctttgacaa gagaaacggc atttcccatt gctactccta gaccagcata
    85381 ttcaatcatg gataagtcgt tctcgttatc tccgatagcc atgatttcat cttgatcaat
    85441 accaaggtgc tgtgcgagat tcgcaactgc cgcaccttta cttgcttctt tatttagtac
    85501 ttcgaagtaa tagggcgcac ttttgaccgt tgtgtattta tcacggaaag tttgcggtaa
    85561 acgcgcaatt gctgcatcta aaatttctgg ttcgtcgatc atcatcattt tgacgatgtt
    85621 catgtctggt gtcatttctt caggtgttcg atattttagc ggcatcttga ctaaacttgc
    85681 ttcgtggatc gtataagcgc tgatatctcg attaggcgtg tagatcgctt tgtcatcgat
    85741 cgaatggaga tgactgccga cacggcgtgc catcacttcg atctctagga aatcttcatg
    85801 agtcagtccg tgacgggcga tgattttacc tgatttcgtt tgttgtacga gtgccccgtt
    85861 ataagtaata acgtaatcat tatcttgaaa aaggttcaac tcgtttaact gttcctggac
    85921 acctggtaag ggacggccag tgcataaaac gatcgaaaca ccttttgcaa cagcagcggc
    85981 aatcgcttct tttacttctt ttgttacttc tcttttctca tttaataaag taccatcgat
    86041 gtcgatagcg actagtttga tagacataat ttcctccaat atattttaat ttatttcaat
    86101 caatgcgcca ttacggatat ggctggcaaa ttcttgataa gtttcgtcaa ataaatcata
    86161 atgatcacgc aaggagggat caaccatttc ttttggaaag aaaaatcgct catctccttg
    86221 ttcttgtccc gctaatgcag caacaagctg actaacctgt gataattcta tcaaagttcc
    86281 gtcatttcgc aaaatctcga tttgtgtgcg atgtctgcct tgttctgggc gataaaaatc
    86341 ataaggcaga tcgtagctag aattcacagc agtgtaataa acagggttat agccaacctt
    86401 ttctactaac aaagtgagtt cttggactaa ttttgaatcc cggttgccag aaaaagtagc
    86461 agatttcagt ggtttacgat tcaaaaaacg tttagctaaa tcatttaaaa taggatcagc
    86521 agattcagac cattgagtaa agtaagtgcc caagacccca tcatcaagtt tgaggtattc
    86581 ttctaaagta aagcttccgt caagaaatgg cagaagtaat tgagaatgga gttcaaaact
    86641 gctggcatct tcttgataca actcgtgtgc gcgatgaagc agatgctcca aaatcacttc
    86701 cataccacgg gaaacaggat ggaagtacac ttgcacatac atttgatatc ggctaacgat
    86761 ataatcttcc actgcatgca tgccactcat ggaaaaagcg atcccgcctt cataaggacg
    86821 aatcacacgt aatattcggg taagatcaaa tgttccatat tctgttccag tgaaataagc
    86881 atcccgaagc aaatagtcca ttcgatctgc atcgatctga ctagaaatca tttggacaac
    86941 ttgtgggttg gggtaagttt tttggatcac actagctacc ttttcaggaa aaccttcttc
    87001 tactcggtta agaatctgat acacttctgt ttctggagaa gtgatgatct ctacagtgat
    87061 ggcttcatga ttcgtatgga agatatgttc aaatgtatga gagtaaggac catgaccgac
    87121 atcatgcaac agtgccgcac ataaagtcac cagccgttcc tgatcatccc agcctccgtt
    87181 gcctattttt tcttttgaaa aatttcgaga aaagatatcg cagattcgtc ttgaaatctc
    87241 ataaacgcct aatgaatggg taaaacggct atgttctgct ccgtgaaaag tgaaagaaga
    87301 agtgcctaat tgtttaatgc gtcgtaaacg ttggacttct ttcgaattga tcaaatctaa
    87361 gattacttta tgctggacat ggatatagtt atggactgga tcacgaaaaa ctttttccat
    87421 aggcagcatt tgatatttat aaggggttgt cataatgtag ctcctttatg ttattacgtt
    87481 gttccattct ctggatttgg ttgttccatt gctccagctg gatttctttt tttagccagt
    87541 cggtagaatc ctgtaaatca cttgcagaat acagcttttc aaaagctttt gcaaatgctt
    87601 ctttgacttc ttttacaaaa aggggttggt caagcagttc ttcaagtgtt gccattgtag
    87661 caggatccac tgcaggatag ccatttgtac caaagtcttc ttttaaagca gattgataaa
    87721 atcgcttcat gacttgcccg cgtttttcct gattaccgtt gacacttaag tacatcataa
    87781 cagaaatccc atttttgatc cgacgctgag cgataccggc aaattttttg ccatggatgc
    87841 ttaaatcata agttccagga caataagaat gggtgatttc gaatgcttgt atcggtgcct
    87901 ttggaaaagc gtatttagtc aataggagca tttgctcgta agcgtcatct atggttattt
    87961 tttttgtgtc actttgaggg aaaatcaaag aaatatttaa aattccttca tctgatacga
    88021 tccctaatcc acctgaattt ctgatcactg gagcgtaacc tgcatctttc agtgtttgga
    88081 tcccgtcact tagaaaagga gttcgaacat ccttcatacc taagatgact gtgcagtcat
    88141 attgccagaa atgtaaaaag atttgctggt gttctttaga atattccgtt aatatatctg
    88201 ttaatgcaaa aggggaaaag tcgttttttt gataaatgtg ctgatctagt cgaatcgcag
    88261 ggttcattca accggctcct ttgtataaat tcatattttc tacaatatta tactctaaaa
    88321 tcaaagagtt gttttggaaa aaaggttttc tgtaaaaatg gacaagttgg ttgacaaaac
    88381 aaaagaaact aggaacaatg tagctatgag aagtaaagga gaatgaataa tggaattatc
    88441 acaaggaaca ccgatttcaa tcaaattgcg tacaaaagta aaacagcaag gggaagtgca
    88501 agatttttat tttgatttga aagggcaaat ggtgacaatt ggcgatacgc tgtacatacg
    88561 ttataaagag attcaggagg agacgggcga tgagattcct gtaacgatca aattagttcc
    88621 agatggtcat gtacagctga tccgtgcagg agaaatgcgg atgcgtttga aatttggcta
    88681 taaagaacgg ttagaaacat cctatcgaac accatacggt atgatccaga ttgctacttt
    88741 tacgaaagaa ctgcatgtta gtttgaaaga ccgtcccaca gcagggaagg ttcgaatcga
    88801 ttatgatctg ttcatgggac cggaaaaaat cggcgaatat tatttgacct tggattttac
    88861 agcgtaaata taaaagaaaa gtttgatttt ttgtgtctga ttttgtatga taaggagtag
    88921 actgtgaaag gacgtgtcct gattggaaat tagtgtattt gaaggtgcaa acaaaagcga
    88981 attatcaatg atcgaagtag cacacgcgat cttagaacaa cgtggcgatg tcatggattt
    89041 ttctgattta gctaaccaga tccaaaacta tcttgagaaa tcagacagtg aaattcgtga
    89101 ttcactcgca caattttata ctgacttgaa tattgacggc agctttatct cattagggga
    89161 taatcgttgg ggcttgcgtt catggtatgc tatcgattcg atcgatgaag aagtaaacca
    89221 tggaatggac gaagaggatg aagatactcc acgtcgccgt aaacgcaaga aagtcaacgc
    89281 ctttatcaat gatgatgaag acgcgatcga ttacaatgac gatgacccag aagatacaga
    89341 tctgacagaa gaagatgacg atgatctgtt tgatgacgat gatgatgaag atgaagaaat
    89401 cgctgcttat aattctgact tgcaagaaat cggagcagat gacccgacag atgatgaaga
    89461 agacttgcca ggaaatatcg aagaagattt aagtatcata gacgaagacg atgatgatga
    89521 agattatgaa gaggaagaat tttctgactc tgaaaaagaa taaacattat tttcttacga
    89581 gaggttgtga cagagacgat cagcctatca gaataaggag gtgtgacacg atttttgtca
    89641 caccttcttt tttgtatata aaaatcccaa gtaaatacat aaaaaataaa aaaattgaaa
    89701 cttttagcgc accttgtacg tcatattaag tgaggcagaa aggagtggag aatgattttt
    89761 actggatata agaaaaaacg gcagatcgaa aaataccgtc acctgctgaa tggactcatc
    89821 gaaactgatt atcaaaaaat gttccgtatc acgatgaatt acgtacatga taaagaagag
    89881 gccttagatg tgatgcaaga tagttttcat aaagccttga actattttga aaaagaaaaa
    89941 gagatcgagc attttagtgc atggttttat cggatattga tccgcacggc attagatagt
    90001 tggcgcagac aaaaaaggac gcctgtggac ttatttgaaa ttcaagatat cccccaacag
    90061 ttacctttag aaacttccgt tgcagagctc catatgattt tagataaaat agacagtccg
    90121 gaaaaagaga ttctgatcct ctactttttt gaaggatttc gtttgaaaga aattgcaact
    90181 atcttggata tgaatgaaaa cacagttaaa acgaaaatgt accgctcatt gaatgcttta
    90241 cgtcaaatcc tagaatgaag gagagaagag tgccatgtat tcccaaaaag aaaatttaaa
    90301 aaaactaaag aaaacttata aagaacaagc aattcccaaa gggcttaaag aggagatccg
    90361 ccagcgtttt attatcgaag agcaatcatt tataaaagca aggcggagaa agagacgtct
    90421 ccaagggttc ggagtatctt tggctatcgt aatgattaca acaagtagcc ttctttttaa
    90481 tagtcaagtt cgaagctttg cagaagattt acccatctta ggatcagtca ttgaattgat
    90541 cttaggcgaa cgctttactg atcgatctga aaaaatcgat attcaggtac cgaagatcaa
    90601 tacacaaaat gagaaagaaa ataaaacaat tcatggatta aatcaaaaat actttcgcga
    90661 aggacaagca gattttgaaa aagctgaaaa agaatatgga aattttgaaa cggatcatta
    90721 ccaagttttg ggagattatc agaaaatcgt agacgataac cggtttctcg tgattgaaag
    90781 gcagatcacc caaacagcag cagatagcca tgttgaaaaa agatacgaca caatcgacaa
    90841 gaaaaacagt gtccagctct cacttccact tttattcaaa gatgacactt atctatctgt
    90901 tttgacaaaa gaagtcaaac ggcagatggc cgaacaagtc aaggaagatc catctaagta
    90961 ctattggact gagcaagata ttcaagaagg gacgatagaa aaaccaacac ttgttacgcc
    91021 tacacgaagt ttttatttga acaaagagca tcaattagtt ttgacttttt ctcaatacga
    91081 aattgctcct ggttatatgg gtacaccaga atttgtcatt cctaagtccg tgacaaaaac
    91141 gattttggca tcggaagatt atttggatca ttagacgaga agtagttgcg actagcagtt
    91201 tcaattttca agtaagtaca agtaaataat aagaagagaa aaagagaaag aagagatata
    91261 gtgaaaagaa attatttagt catcagtatt attgctttat ccgtgctttt gtttttcgaa
    91321 attacttcgg tggcctcctt gatcaccgaa gtaaaaggac aaacacactc ttcggagcat
    91381 tcgtcacaat ctttcaaaca atcagaacaa tcaaccatta aaagccaatc aactgaaaca
    91441 gctaacgtca aagaagccat tcaagaatca gcggaaaagg tacaaagtca atcatcacaa
    91501 tcaacacaag acagtacaga agcaatccaa gacccgactg tcaaaagcgt cgcaatcagc
    91561 tttgatgatg gaccaggagc gaccacaacg ccgcagcttc tgcgaatctt aaaagaaaaa
    91621 aacgtgcatg tcactttttt cgtcttagga gaaaatacgg cgcagcatcc tgaaatcgtg
    91681 aagcagacag ctgaagcagg gcacgagatt ggcaatcaca catacgatca tcagaatctg
    91741 gccactcttt ctgcccagtc gatgacggag gaagtgacga aagcagacac tgagatcaaa
    91801 aaaagtcact ggcaaaaccc ccgcttttgt tcgtccgccc tatggttctg tcacgaatgt
    91861 aggagcaacg atcatccagc gaccgatcat cgaatggtct gttgattcag aagattggaa
    91921 gacaaggaat cctgatttga ttttgcagaa gatccaagca acagtatacg atgggtcaat
    91981 tattttattc catgatatct atcctgaaac gattcgtgcc gttcctcaag tgatcgatta
    92041 tctgaaagag caaggctatc gcatcacgac agttagcgat ttattagggc atccaacggc
    92101 tgtcgagaac tattatggca gaaacgatca tcggccagtt cagtaagtga gacaagtatc
    92161 tttaataaat aacacatttt aataagtagt tgaacacata actaccttac ttgcaaaggc
    92221 ttaa
//
LOCUS       DAFBVQ010000006        90176 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.006, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000006 DAFBVQ010000000
VERSION     DAFBVQ010000006.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 90176)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 90176)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..90176
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.006"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(204..287)
                     /locus_tag="LLC22_000486"
     tRNA            complement(204..287)
                     /locus_tag="LLC22_000486"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(251..253),aa:Leu,seq:gag)
     gene            342..521
                     /locus_tag="LLC22_000487"
     CDS             342..521
                     /locus_tag="LLC22_000487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433788.1"
                     /translation="MGGLIKMEKYDGEFSGLGMILGVLIGLAFGRFLLGFMLGIICGI
                     AMDWAANLWNDYHDN"
     gene            670..1887
                     /locus_tag="LLC22_000488"
     CDS             670..1887
                     /locus_tag="LLC22_000488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5433789.1"
                     /translation="MREFEKSNKLEGVSYDVRGPVLEEAERMQEEGISILKLNTGNPA
                     PFGFEAPNEVIRDLIMNARDSEGYSDSKGIFSARKAIEQYCQLKHFPNVTINDIYTGN
                     GVSELITMCMQGLLDNGDEVLVPMPDYPLWTASIALAGGTPVHYICDEEAEWYPDIDD
                     IKSKITSRTKAIVIINPNNPTGALYPKELLEEIVEVARQNNLIIYSDEIYDRLVMDGL
                     EHIPIATLAPDLFVVTLNGLSKSHRVAGFRVGWMVLSGDKSHVKGYIEGLNMLSSMRL
                     CSNVLSQQIIQTALGGYQSVDELLLPGGRIYEQREYIYNAINDIPGLSAVKPKAAFYI
                     FPKIDTKRFNILDDEKFVLDFLHEHHILLVHGGGFNWNQPDHFRIVYLPKMDDLKQTA
                     KKMREFLATYRQK"
     gene            2071..2907
                     /locus_tag="LLC22_000489"
     CDS             2071..2907
                     /locus_tag="LLC22_000489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5433790.1"
                     /translation="METLIESFGTIIKEIRKEQKMTQKMLSHDICSQSVLSRIENNEE
                     LPNVLVMMQICQRLGVTIDHVMNLSRKTTRTNDKLFELLDSCFQKRDYRKLEQVLKSS
                     DISENLYQATDFQRYYYYLGVCEFTLRQNISQSLYYLKEALSYSSQKERIHVSDTEIQ
                     LISCIGKIYGVAGKTAEARYYLSRSIQLLHQSADERSKSEFSQIFYNYGNFLFHQNEI
                     DEALEQVNQGIYWAQEKNSYYYLNDLFVLKSLIYKRKEEPERAAFYEGLAQAVKQISK
                     NL"
     gene            2983..4131
                     /gene="nagA"
                     /locus_tag="LLC22_000490"
     CDS             2983..4131
                     /gene="nagA"
                     /locus_tag="LLC22_000490"
                     /EC_number="3.5.1.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylglucosamine-6-phosphate deacetylase"
                     /protein_id="HBK5433791.1"
                     /translation="MRTFIYADKFFLASGVKHAGYLEITDGLFGEYTKELPEGEVNII
                     DQSGKWIAPGLVDTHIHGYMNHDVMDNDAEGIKVMSEGLLSCGVTSFLPTTLTSSKER
                     LKDVAETIGKMYQEAPGAKIKGIYFEGPFFTEEHKGAQNPSYFGDPDLDTFHEWQEAS
                     GGLIKKIALAPERQGVEEFVKQVTEEGVVVSLGHSNATLEEAQKAVEAGASVFVHAFN
                     GMRGLNHREPGMVGALLSLEHVFSELICDGHHVHPNAAGILMEKAGHDHVALITDCMM
                     AGGMPDGNYNLGEFPVVVKEGTARLESGNLAGSILKLKEAIKNVVDWGLATPEQAVMM
                     ASLIPAISCKIDDTCGKIAQGRDADFIVLNPDMTLEATYLDGVERFHA"
     gene            4352..5410
                     /locus_tag="LLC22_000491"
     CDS             4352..5410
                     /locus_tag="LLC22_000491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AEC family transporter"
                     /protein_id="HBK5433792.1"
                     /translation="MNLFDIFRSTLTDMSIVSAITSTVFIILLGFVCRKKGIFSESVG
                     KILSKVVLTVALPALAFRAFMQDINTELLMQGINVLIWGLVIYIILILVSKPFFLSYK
                     GDKQTTLRVLTIFGSTTFFGTPIVSAIYGPVGVMYSSIFNIGYRIFLYSYGYIKMSGL
                     KMEAKNIKAMFVNPIIIATFAGLFIWLFQGYLPQVSVTGAEGEISQVAFLRIDQTAPW
                     LFQPMDYLAGLSSPLAWLAIGATLGEVSFKKAASEKTSWYYSLVKVVFVPALNIVILA
                     VLTATNILPVNFEALATIVIMMATPAATVAAAYAISFDREALLASNASLLSTIFAVVL
                     TPVWIVVLQMIHGIGLFS"
     gene            5414..6448
                     /locus_tag="LLC22_000492"
     CDS             5414..6448
                     /locus_tag="LLC22_000492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactate dehydrogenase"
                     /protein_id="HBK5433793.1"
                     /translation="MEEESMRIACYGVRPNEIDFFEKLNIYHYDLSLYEELLTHDNIV
                     SAKDHDAVLLRGNCIADETNLAKMQEYGIRYVFTRTVGVNHIDLQAAADFGMTVARVP
                     SYSPNAIAELSLTFAMMLLRNTAYTTIRTSFKDFRVDEQMFSREIRNCTVGIIGTGRI
                     GLTEAVLFKGLGAKVIGYDIHQTEAAKKVLTFHSLEELLAKSDIVSIHVPHIPGENDQ
                     MINEGFLAQMKKGSILINTARGELQDNEAILRALKSNHLAGFATDVFANETEVFFRSF
                     KPWETIPDPAIQQLVEMYPRVLVTPHVGSNTDEALSNMISTSFENFREIIETGKTKNE
                     VSLPKARQLR"
     gene            complement(6550..7266)
                     /locus_tag="LLC22_000493"
     CDS             complement(6550..7266)
                     /locus_tag="LLC22_000493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK5433794.1"
                     /translation="MMTNVLIIEDDPMVAELNRTFVESIPNMNVIESFRNVEEGKKYF
                     RQKNADLLLLDVYMPGESGIHFLSWLRQQGNDIPVILITAADDIETIKNVIRYGALDY
                     LIKPFTLQRFQLAIEKYLAFSQTIQTTEKADQKLIDQVFNHTTPIHEIPSFIDLPKGL
                     SKLTLKKISAFILKEDTIFSTKELAQKSSLSRISVKKYLNFLVEQDILNERIKYLEIG
                     RPLTCYELTKNGRKKLTDYC"
     gene            complement(7235..8020)
                     /locus_tag="LLC22_000494"
     CDS             complement(7235..8020)
                     /locus_tag="LLC22_000494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spo0B domain-containing protein"
                     /protein_id="HBK5433795.1"
                     /translation="MYLNGIETISSVTPLFSNDRFLGAVATLRNRSEVMKLMEELGGT
                     KQYINSMRAQTHEFMNKLHVISGLIDLKKYEEVTHFIQQLNQNYKKEIGQVSSLIKVP
                     AIAGFLLGKINEAKEQSVEMLLESDSFIPKMEMDDSIHSLLQVLGNLLDNAKEAVLQK
                     HERNGQVRIHLNYDTEAEVFIVTVCDDGVGISEEISEKIFTLGFSTKGINRGFGLNLI
                     HSIVKRHGGFLEFSKQTNGGTIVYLELPKKEDQNDDKCPDNRR"
     gene            complement(8011..8760)
                     /locus_tag="LLC22_000495"
     CDS             complement(8011..8760)
                     /locus_tag="LLC22_000495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK5433796.1"
                     /translation="MNRSSVSDKISSIAKIVANDKLIQKKLQTGDPTHAIQGITNEIM
                     IASNLDFIVVMDPEGIRYSHADPSYIGLPFSSHEDVKKVIGGQEFFSEKEGMLGFGFR
                     YFVPIYYDQEIIGAVCVGLTNNTIDNQVKDGQKMIVFSLIIGLSVGIIGAVFLAQKMK
                     KVLLGLEPQEIAEQLSEKTIIENEVDEGILAISSDKTILLINTPAKNIFYQTEQLLDF
                     EVGKKSVIIYMTFCLKRRLSIKRPFGLNPCI"
     gene            9058..9582
                     /locus_tag="LLC22_000496"
     CDS             9058..9582
                     /locus_tag="LLC22_000496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NfeD family protein"
                     /protein_id="HBK5433797.1"
                     /translation="MIGGIALETIYWYTLLICAGLAVLLIIFGDVFDFDGPLDPMLII
                     PWLTFTSLFGFLGERLTDQSSLFLFIASGGISIVLVFLLNFYILMPMKHAESTMSSSE
                     KTLEGQVAVVITPIPVRGMGEIQLKSVTGSISRPACFYSPQEQTAERGTKVLIIEIKE
                     RICYVMPYESMIKA"
     gene            9598..11097
                     /locus_tag="LLC22_000497"
     CDS             9598..11097
                     /locus_tag="LLC22_000497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flotillin family protein"
                     /protein_id="HBK5433798.1"
                     /translation="MEIPVVFIAIAIAALILLMLLIVFVAKYQTAKPDEALIISGSYL
                     GSKNVHIDESNNKIKIVRGGGAFVLPVFQRSNRISLLSSKLDVSTPEVYTEQGVPVMC
                     DGTSIIKIGSSVEEIATAAEQFLGKTREELENEAREVLEGHLRSILGSMTVEEIYQNR
                     DKFSQSVQEVASVDLAKMGLIIVSFTIKEVRDKNGYLDSLGKPRIAQVKRDADIAEAE
                     ALKETRIKKAQAEKESQAAELQRQTEIAESLKEKELKLATYKQEQDVAKAKADQAYNL
                     ESARAQQQVIEQEMQIKIVERQKQIELEEKEITRREKQYDSEVKKKADADRYAKEQEA
                     QAQKVKEVTEAEAERFRVEALAEAEANKTRLAGQAEAEAALAKGKAEAEAKQKIANAF
                     KEYGEAAVLSMVIDMLPQLMREAAQPLGNIEKISVVDTGSSSGETSGANRVTNYATNL
                     LSSTQETLKATTGLDLKEIVENLSTRGTTSQVNMYEAPKEAEQNSMKEE"
     gene            complement(11185..11787)
                     /locus_tag="LLC22_000498"
     CDS             complement(11185..11787)
                     /locus_tag="LLC22_000498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339383.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5433799.1"
                     /translation="MQFGRFRLGMRTIKSALAVFLCILFFHLTQRGIPMIAALSAVFS
                     LRQDLTTTVSFGKSRIIGNTLGGTLAIIYFFVKSYFHNDFLVELILLPILVIIVIVVS
                     DGINNNSGIISAIATLLLIALSIPQGESALYAIQRVLDTFIGTFIAIGINFFLRPPET
                     EKKEELSEDLVELQKKERLLRTNLQEIEAKIQKQKKNSED"
     gene            11891..12847
                     /locus_tag="LLC22_000499"
     CDS             11891..12847
                     /locus_tag="LLC22_000499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aromatic acid exporter family protein"
                     /protein_id="HBK5433800.1"
                     /translation="MRIGMRTVKTVISVFFSMVTAGSLSLLYWPAAGIIALLSVGNTK
                     RSTLRTGMNRIAAFILATATALFSFFAVGYTIFGFSLFLFLFIPLASRFKLTEGIVVN
                     SVLVTHYLVEENMSWQLIGNEAGLMAIGLVFALLANVYMPDRTKQLKENQIQIEKEFR
                     NILRQMAEFLLSENKEDVQIKCEHLLTFIRESQEDAREHQENYWLRQPLYYETYFSMR
                     RAQANVIKDMLENLERIQQPAYYGKHIYGLLIYTAETFSESNDGRQILTRIEEVYVLY
                     RQMPLPTSRPEFEDRAELFQFLQSFKSFIEIKAEFSQQKIQK"
     gene            complement(13152..14108)
                     /locus_tag="LLC22_000500"
     CDS             complement(13152..14108)
                     /locus_tag="LLC22_000500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5433801.1"
                     /translation="MKKYQWGIVGLGTIAHEFAESFNQETSELTAVASRTSEKAENFA
                     HRYNIPKAYGSYQEMLDDAEIDIVYIAVPNRQHIDHILAALEAGKHVLCEKAITMNKK
                     ELADAMRLAEEKNLILAEAMTIFNMPLYQQLRSIMDTGKLGALKMIQAPFGSYKEPDP
                     KNRFFNPELAGGALLDIGTYAVSFARFFLSSQPEVVASTMVPFETGVDEQSVTILRNK
                     ENELAAVSLTFQAKMPKVGIVAFENGYVTIADYPRADRAEILFTDGTKEFIESGNTSE
                     AMNYEIKNMVHMIEGDLPNRSLFLTKDVIEILDQMQVLWKNM"
     gene            14282..14842
                     /locus_tag="LLC22_000501"
     CDS             14282..14842
                     /locus_tag="LLC22_000501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433802.1"
                     /translation="MHQVYIDLIMSVLLEQFETEKNFLDEYLLISPEQWQKWKDGEKN
                     LPSEAMQKVKNLFTDYEWMLTQKILRQTIIFPEKRNVAVAEYKQIKTRIAQKWLSSKA
                     AKVELIPLKNNQQAGRYLDLKVSIQYDEWGYDDILNFRLPADVQKQIEGEKIELLDWV
                     NENLEETYVHEANGEREEQRKDFSSE"
     gene            14835..15659
                     /locus_tag="LLC22_000502"
     CDS             14835..15659
                     /locus_tag="LLC22_000502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M15 family metallopeptidase"
                     /protein_id="HBK5433803.1"
                     /translation="MNKFLGFGAVVIMIAAMGYVIFSDDDSHVQAGNQAVERTSTKTT
                     ASKEKNSQTTSSKVKDKETKDRTSKQLPDVKTDDWKLVLVGPDHKLEKEIDESTQLAS
                     LSNGYLIDKRIAPEYEAFAKAAEAAGFPLVMVSAYRSVSSQQQVFEQNVQDVMSRQGV
                     SEEEATKITKETITEPGYSEHHTGLAVDVVDQNWYNSYPSTVLDASYGDQPGAKWIAD
                     NAAQYGFIVRYPKGHEDITKITYEPWHLRYVGKENAEYITKHQLTLEEYLNELNEK"
     gene            15669..16286
                     /locus_tag="LLC22_000503"
     CDS             15669..16286
                     /locus_tag="LLC22_000503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBK5433804.1"
                     /translation="MAKKKWKKQKRKNIRWPAVVAGVAVILLAFVFSLKNLSSPFTDN
                     QQENEAQSHQQFIERLVPHAQELQDGYGVLPSIILGQAILESNWGKSTLASKYNNLFG
                     IKAYGDQKKVSLETKEFVNEEWITIQGDFKVYDSWEQSMDDHTQLFVQGVDWNPALYE
                     KVITATNYQEAAQALQDAGYATDPGYAQKIIQVIETYQLNQYDRR"
     gene            16304..16987
                     /locus_tag="LLC22_000504"
     CDS             16304..16987
                     /locus_tag="LLC22_000504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBK5433805.1"
                     /translation="MAEQFTPEIMTELRKDIVRVPEIILEASGIKIFGKLIRSIIFTT
                     DIAIIRNTNANAVIAVYPFTPHPAITKSIIEAADIPVFSGVGGGLTQGARSSYMSMFA
                     EAQGSLGVVLNGPTPLETVKEVCRVVDIPVISTVTSKYTEIDEKLAAGISIINISAGK
                     ETAEAVRHFRKKYPELPIIATGGPTEESIAETIQAGANAITYTPPSSGELFSRKMEKY
                     RETEKKNHE"
     gene            17670..18953
                     /locus_tag="LLC22_000505"
     CDS             17670..18953
                     /locus_tag="LLC22_000505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738728.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5433806.1"
                     /translation="MKKRMRIILALSVMLFFLTACGQEDDKKITLNMAWWGSQVRHDA
                     TVKVIELYEEKNPHVTIDYEFYDYEGYYTKLGTLAASDDIWDIFQLNNQFPQYINQIE
                     PLDEYVEQGIIDISNADESYLATTTYDGQLVGLSNGVNSFAIAYNKNIFEQLNIPEPA
                     SNWTWDEFEQISYQITEELGIYAISRFEDFIAGCIIQIPQVEKGLNFYNREDLSNSLG
                     FENPDYLTDFFQLRKNLVDKGAHPEPGGGAASTTDLSFQAVRDREAAMVFLSSNQLTE
                     ILSGAPEDMEIQLINPPRRKADGESGIPLRSSQMLSMAKSSAHKEEAAKFIDFFQNSE
                     EANEILKGERGVPIMSNIREQLARADDATLQATFDYLEMISDMDNGEVNVFDSALNPE
                     IQDQYNLLVEKVIYEEVTAEEAAESLYEFASNILG"
     gene            18969..19856
                     /locus_tag="LLC22_000506"
     CDS             18969..19856
                     /locus_tag="LLC22_000506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5433807.1"
                     /translation="MKKEKLKRFLDQDNVVGYVFASPFILGFLLITVIPMILSLYYSF
                     TDYRLGNPVSWIGLDNYIKMLSDARFLNSIRVTFLYVFASVPVKLIFGLLIAYLLTRN
                     IKGTTFFRSLYYVPSLIGGSISIALVWRELFSKNGLVNIFLERLGAPALSWFSDQKLV
                     MIPLVLMSAWQFGSAMIIFAAGIKEIPGSYYEAAEIDGANKWQTFYKITLPLLSPIIL
                     YNLVMQTIAAFMTFTQAFIITQGGPNDATNFYALYVYNQAFSFNSMGYASAISWIMLL
                     IMGAVTFLIFKSSKKWVVV"
     gene            19873..20709
                     /locus_tag="LLC22_000507"
     CDS             19873..20709
                     /locus_tag="LLC22_000507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5433808.1"
                     /translation="MNNTVTKWFQYGFILLLGLVMIYPVLWMIAGSFKTDQEIMSGSL
                     NLIPETFQWENYAKGWAGFAGISFFTFFRNSFVISAVSTIGTVLSSTCIAYALSRIDF
                     KGKRFWFVVMLVTMMIPAQVILIPQFIIYNRLNLVGTYVPLILPHFFGQAFFIYQIMQ
                     FMVSIPKELDESAIIDGCSKYSVFTKIIFPLLKPSIITTIIIQFYWKWDDFMGPLIYL
                     NKPRSYTVSIAIKLFADAGSSTTYASMFAMSTLSLLPVFLIFLFFNKYLVQGISTSGL
                     KG"
     gene            20712..21335
                     /locus_tag="LLC22_000508"
     CDS             20712..21335
                     /locus_tag="LLC22_000508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433809.1"
                     /translation="MKKPIEEMFLYKLNYYVCRIFLTSLISNALFALVLGCLFTLGLV
                     LSARVVYLIYFLMMYPSYYLSVHYLAEKKVCWRKGKIKRMCFIITLFQLFVIIFAVDW
                     YLLVGKIGAWYLIPFLLCLLLFVSHSFFSTLIDICKEDKADSLVYLIKRNIWLLSKNV
                     KGFLWYLCLLYGLFWCIQHDFLLTALLYPGLPFVTVFCLKEKENDFK"
     gene            21332..22624
                     /locus_tag="LLC22_000509"
     CDS             21332..22624
                     /locus_tag="LLC22_000509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738727.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5433810.1"
                     /translation="MKKKYVQVGLGGRARFFYEAIASTYHQTCELVGFCDVSQTRMDY
                     ANRILVNKYGQKKVKTCMPSQFEQLLDDVRPAEVIITSVDRTHHDYIIRAMKKGYDVI
                     CEKPLTIDEEKAQEIITVQKQTGRSLRVTFNYRYAPYHTKIKELIESDVIGDVFSIHF
                     EWLLNTQHGADYFRRWHRNKHNSGGLLVHKSTHHFDLVNFWLNSRPQKVFAFGGLNFY
                     GMHNAEKRGVEIFYSRCYGSELAKADPFAIDLSANEELREMYLEAEKDSGYIRDRSVF
                     SDDISIEDTLGVTVKYETGAILTYSLNAYMPWEGFNVSFNGSKGRIEMKVIEKSYINA
                     GGDKKDEGAAVLQSIHVYPMFGEPYEVIVEQEAGGHGGGDPRLLDDLFGEEKEEDPWN
                     RAATHVDGILSILTGIAANHSIASGKAVVIDELVSLKE"
     regulatory      22983..23080
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00167"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="purine riboswitch; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="guanine and/or adenine"
                     /db_xref="RFAM:RF00167"
     gene            23196..23777
                     /locus_tag="LLC22_000510"
     CDS             23196..23777
                     /locus_tag="LLC22_000510"
                     /EC_number="2.4.2.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xanthine phosphoribosyltransferase"
                     /protein_id="HBK5433811.1"
                     /translation="MKELVERIQKDGRILGEGVLKVDSFVTHQVDPVLMEQMGKRFAE
                     VFKEQGITKVVTIEASGIAPALFAARELDVPMIFARKAKSLTMDEELLTASVYSFTKQ
                     VTSTISISRKFLSSEDKVLIIDDFLANGQAAKGLIELCQQAGAQVEGIGIVIEKSFQD
                     GRQLLEEMGLRVVSLARIASLTNGQVEFLEEDA"
     gene            23780..25087
                     /locus_tag="LLC22_000511"
     CDS             23780..25087
                     /locus_tag="LLC22_000511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306869.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine permease"
                     /protein_id="HBK5433812.1"
                     /translation="MEKETQNGKAAVLGLQHLLAMYAGAVAVPLLIGTGLGFNQEQMT
                     YLISIDIFMCGLATLLQLTVNRFFGIGLPVVLGCAIQAVAPLILIGTNEGVGAIYGSI
                     IASGIFVVLVSGVFSKIKKLFPPIVTGTVITVIGLTLIPVAIEKMGGGNATAADFGDK
                     TNLLLAFVTILLIVGVQMLAKGFIRSIAVLIGLVGGSILAAFMGMIDLSAIGDAPLFH
                     VPQPFYFGKPTFDVWSILLMIIISMVSMVESTGVYFALGDITGKNVGEEELKKGYRAE
                     GLAVILGGIFNTFPYTGFSQNVGLVQLSGIKTRKPIYFSAFFLIVLGLFPKIGALAQI
                     IPEPVLGGGMLVMFGMVAVQGIRMLLEVDFSNDKNLLIVAVSVGFGLGFNVTPTLFSQ
                     MPQTLQMFTGNGIVMSSITAIILNLIFNGLKKDEEILEEAFKK"
     gene            25503..25991
                     /gene="purE"
                     /locus_tag="LLC22_000512"
     CDS             25503..25991
                     /gene="purE"
                     /locus_tag="LLC22_000512"
                     /EC_number="4.1.1.21"
                     /EC_number="5.4.99.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide mutase"
                     /protein_id="HBK5433813.1"
                     /translation="MTAKISVIMGSTSDWETMKEACQILDEFGVSYEKKVVSAHRTPD
                     LMFEYAQNARKKGIKIIIAGAGGAAHLPGMVASKTTLPVIGVPVQSRTLNGLDSLLSI
                     VQMPGGVPVATTAIGKAGAINAGLLAIQMLSMYDLELEAKLAERRSMLAKTVIESSDQ
                     LG"
     gene            25984..27108
                     /gene="purK"
                     /locus_tag="LLC22_000513"
     CDS             25984..27108
                     /gene="purK"
                     /locus_tag="LLC22_000513"
                     /EC_number="6.3.4.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-(carboxyamino)imidazole ribonucleotide
                     synthase"
                     /protein_id="HBK5433814.1"
                     /translation="MVKPLLPGSTIGIVGGGQLGRMMAISAKEMGFKVGVLDPVSDCP
                     AAQVADWHIESVYDDTFALKELARRTDVITYEFENVSVEALNAILPMSFIPQGTDLLA
                     ITQDRLLEKSFLETNNIVIAPYATIVSPTDIQDAIDGIGYPCVLKTTRGGYDGKGQYV
                     LKSRADLAPAMDLLREGTCVLEAWIPFEKEISIMVAGNGQGDFTTFPVVENIHHNNIL
                     HETIAPAAIDQDVIEEAERIARVIAEAVSLSGVLGVEMFLTKTGGLYVNELAPRPHNS
                     GHYSIEACSMSQFDAHIRGICGWPLGEKVRLISNAVMVNVLGEQLLESYRLIENKPDW
                     QFHFYGKKQAKKGRKMGHITILTEDIQQTLEEIKQTNIWD"
     gene            27121..28416
                     /gene="purB"
                     /locus_tag="LLC22_000514"
     CDS             27121..28416
                     /gene="purB"
                     /locus_tag="LLC22_000514"
                     /EC_number="4.3.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate lyase"
                     /protein_id="HBK5433815.1"
                     /translation="MLERYTRPEMGNIWTEENKYRAWLEVEILADEAWAELGEIPQED
                     VKKIREHASFDIDRILEIEKLTRHDVVAFTRAVSETLGEERKWVHYGLTSTDVVDTAY
                     GYLIKQANDILREDLKRFTEIIGEKAKEHKYTVMMGRTHGVHAEPTTFGLKLATWYSE
                     MKRNIERFEHAAKGVEAGKISGAVGTFANIPPFIEEYVCKQLGIRPQEISTQVLPRDL
                     HAEYFSAMALIATSIERFATEIRGLQKSETREVEEFFAKGQKGSSAMPHKRNPIGSEN
                     MAGLARVVRGHMVTAYENVTLWHERDISHSSAERIILPDTTILLNYMLNRFGNIVKNL
                     TVFPENMKRNMSATFGLIYSQRVMLKLIDKGMTREEAYDLVQPKTAYAWDNQVQFRPL
                     LEEDPTITSVLSKEEIDDAFDYHHHLKNVDVIFKRVGLE"
     gene            complement(28596..28973)
                     /locus_tag="LLC22_000515"
     CDS             complement(28596..28973)
                     /locus_tag="LLC22_000515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433816.1"
                     /translation="MEDAIKQGQLFLSELTAEERSCLYNDLLSIKDVYLCNKDTSFYT
                     FRKIRRATKRCAECRKRTFLYQTEHKGELSISQIHEQKRFKNHYRIQILFNGQEMEYA
                     FLENLLQHLHNQHFSYNSQAIYA"
     gene            29229..29957
                     /locus_tag="LLC22_000516"
     CDS             29229..29957
                     /locus_tag="LLC22_000516"
                     /EC_number="6.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylaminoimidazolesuccinocarboxamide
                     synthase"
                     /protein_id="HBK5433817.1"
                     /translation="MEKKELLYEGKAKKIYLTSDENLIWIEYLDQATALNGARKDQIS
                     GKGELNNQITSAIFRYLTQRGIKNHFIEQLSKTEQLAKKVQIIPLEVVIRNIAAGSFS
                     KRLGVPEGKEFIKPIIEFYYKDDQLDDPFINEEHIYFLQLAKPEEISELKAQALAINE
                     ILTELFAKVGLVLVDFKLEFGRSNGQILLADEVTPDTCRLWDERTNEHMDKDVYRRDL
                     GDLIPVYQEVYNRLSELTEEKERV"
     gene            29957..30211
                     /gene="purS"
                     /locus_tag="LLC22_000517"
     CDS             29957..30211
                     /gene="purS"
                     /locus_tag="LLC22_000517"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurS"
                     /protein_id="HBK5433818.1"
                     /translation="MYFVKVYVTYKDSVLDPQGEAVKKAVHRMGYETIEDIRIGKYFE
                     IQLADAEEPIDTVIETICDKLLANVNMETYRYEIKKMEEV"
     gene            30213..30884
                     /gene="purQ"
                     /locus_tag="LLC22_000518"
     CDS             30213..30884
                     /gene="purQ"
                     /locus_tag="LLC22_000518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurQ"
                     /protein_id="HBK5433819.1"
                     /translation="MKFAVIVFPGSNCDADMLWAVREIMGADAEFVRHDESSLEGFDG
                     VLLPGGFSYGDYLRCGAIARFSTIMEEVIRFAEEGKPVFGTCNGFQILTEAGLLPGVL
                     RRNESLHFICKTVPLKVNPKTAFTSEYEADEIIYLPVAHGEGNYFCDEETLQELKKNN
                     QIAFTYNDNINGSVENIAGITNKAGNVLGMMPHPERAVEDLLGSEDGKRFFASILKNF
                     GKVTV"
     gene            30885..33107
                     /gene="purL"
                     /locus_tag="LLC22_000519"
     CDS             30885..33107
                     /gene="purL"
                     /locus_tag="LLC22_000519"
                     /EC_number="6.3.5.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine synthase
                     subunit PurL"
                     /protein_id="HBK5433820.1"
                     /translation="MKTLKEPTAEEIKKKRIYAEWGLTDEEYRMIEEDILGRMPNYTE
                     TGLFSVMWSEHCSYKNSKPVLRKFPTSGPHVLQGPGEGAGIVDIGDGLAVVFKAESHN
                     HPSAVEPYEGAATGVGGIIRDIFSMGARPIALLDSLRFGELDNPRTKYLLEEVVAGIG
                     GYGNCIGIPTVGGEIAFDPCYEGNPLVNAMCVGLIEHKHIQKGQAAGVGNSIMYVGAK
                     TGRDGIHGATFASEEFNQEEEQQRSAVQVGDPFMEKLLLEACLELILHHSDSLIGIQD
                     MGAAGLVSSSAEMASKAGSGLILTLDEVPQRETGMTPYEMMLSESQERMLICVKSGEE
                     EKIQELFQKYDLDAVTIGKVTDDGQYRLYHQGEEVANLPVDALAEDAPVYHKEMKEPA
                     RIVEFQQLAPYQPVIEEPGQVLLDLLQQPTIASKRSIYETYDSQVQTNTVVRPGSDAA
                     VMRVRGTNKALAMTTDCNARYLYLDPKIGGQIAVAEAARNIIASGGKPLAITDCLNYG
                     SPDKPEVFWELSTSADGIAAACETLGTPVISGNVSLYNETDGQAIYPTPMIGMVGLIE
                     DHKHITTQEFKKSGDLIYILGKTFADFDGSELQKMQLGRIEGVIRNFDLSIEKRNQEL
                     VLTAIQNGLIESAHDCSEGGLAIALAESAFKHQLGISVQFELSSAQLFAETQSRFVLT
                     VAPENKTRFEEMMGDAAVLAGKVTDEAIIEISATDGQIKIETAVARKCWEDAIVCLMK
                     "
     gene            33092..34531
                     /locus_tag="LLC22_000520"
     CDS             33092..34531
                     /locus_tag="LLC22_000520"
                     /EC_number="2.4.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidophosphoribosyltransferase"
                     /protein_id="HBK5433821.1"
                     /translation="MSYEVKSLNEECGIFGVWGHPDAASVAYFGLHSLQHRGQEGAGI
                     VSNDRGKLKGHRDLGLLSEVFKDQRKLQQLTGEAAIGHVRYATAGNGSVDNIQPFLFK
                     FHDQSIGLAHNGNLINARSLRKELEENGAIFHSNSDTEILMHLIRRSEETDFLNKLKS
                     ALNEVKGGFAYLLMTETAMIAALDPNGFRPLAIGQMKNGAYVIASETCALEVIGARFI
                     RDVQPGEIVIINDEGIQIDCFTKDTQLSICSMEYIYFARPDSNIAGINVHTARKNMGR
                     NLAKESPVKADMVVGVPNSSLSAASGYAEASGIPYEIGLVKNQYIARTFIQPTPELRE
                     QGVRMKLSAVRGVVEGKKVIMVDDSIVRGTTSRRIVHLLKEAGAKEVHVRIASPPLKY
                     PCFYGIDIQTRKELIAANHTIDEIKECIGADSLGFLSEEGLIESIGLEKDAPYSGLCM
                     AYFNGDYPTPLYDYEEKYQESLKEKVSFF"
     gene            34554..35606
                     /locus_tag="LLC22_000521"
     CDS             34554..35606
                     /locus_tag="LLC22_000521"
                     /EC_number="6.3.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylformylglycinamidine cyclo-ligase"
                     /protein_id="HBK5433822.1"
                     /translation="MNSMANAYAKAGVDVEAGYEVVERIKKHVKKTERLGMMGAIGGF
                     GGCFDLSVFQLKEPVLVSGTDGVGTKLAVAIEADKHDTIGIDCVAMCVNDILAQGAEP
                     LYFLDYLATGKNDPLRLENVVKGVADGCVQGNMALIGGETAEMPGMYSGNDYDLAGFA
                     VGIAEKSQLLTGETINPGDVLLGIASSGIHSNGYSLVRKIFFEQQQFSLSSKLPELKK
                     TLGEELLEPTKIYVSSLLPLIKEKKIKGAAHITGGGFVENIPRMLPESMAAQIKLGSW
                     PILPIFGCLQKYGEIPEMEMYEIFNMGIGMVLAVEESKVKEIVHEIEQAGEKVYEIGK
                     VIAKEKHRVVFIGEER"
     gene            35603..36181
                     /gene="purN"
                     /locus_tag="LLC22_000522"
     CDS             35603..36181
                     /gene="purN"
                     /locus_tag="LLC22_000522"
                     /EC_number="2.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylglycinamide formyltransferase"
                     /protein_id="HBK5433823.1"
                     /translation="MRIAVFASGNGSNFQALADYLSKKGLESSIDWLFCDQPEAYVLK
                     RATALSVPADCFSPKEFDSKKEYEEAILHKLKEKKIDLIVLAGYMRIIGPVLLKNYDK
                     RIINIHPSLLPAFPGLHGIRDAFEAGVKETGVTIHYIDQGVDTGPIIRQEKVRIEQED
                     TFDSLEEKIHRVEHRIYPEVISEIIENGGYLK"
     gene            36178..37713
                     /gene="purH"
                     /locus_tag="LLC22_000523"
     CDS             36178..37713
                     /gene="purH"
                     /locus_tag="LLC22_000523"
                     /EC_number="2.1.2.3"
                     /EC_number="3.5.4.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional
                     phosphoribosylaminoimidazolecarboxamide
                     formyltransferase/IMP cyclohydrolase"
                     /protein_id="HBK5433824.1"
                     /translation="MTRALISVSDKTGIVAFAQGLIEQGVEIISTGGTKHALDKAGIK
                     TLSIEEVTGFPEMMDGRVKTLHPKIHGGLLGRRDLPSHMEAMETENIQPIDFVCVNLY
                     PFKETIMKPDVEIAEAIENIDIGGPSMLRSAAKNHEFVTSVVDPSDYEEVLSELRQYG
                     HTSLSFRQKLAAKVFRHTAAYDALIAQYLTDWVEEKEPEKLTLTYERKQTLRYGENSH
                     QAAAFYQSALLEKYSIAAAKQLHGKELSYNNIRDADAALRIMKEYDEPTVVALKHMNP
                     CGIGTASTILEAWEAAYEADPVSIFGGIIVLNREVDLPTAEQMHKLFLEIIIAPSYTQ
                     EALELLQKKKNIRLLTVDFAQEENQNREETVSVLGGLLVQDQDLAIENEEEWKVVTKR
                     KPTPAEAKALVFAWRAVKHVKSNAIVLANERQTVGIGAGQMNRVGSVKIAIEQAQEKM
                     EGAVLASDAYFPMDDSVEYAAKHGIKAIIQPGGSIKDQDSIDMANKYDLAMVFTDVRH
                     FRH"
     gene            37729..39003
                     /gene="purD"
                     /locus_tag="LLC22_000524"
     CDS             37729..39003
                     /gene="purD"
                     /locus_tag="LLC22_000524"
                     /EC_number="6.3.4.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoribosylamine--glycine ligase"
                     /protein_id="HBK5433825.1"
                     /translation="MNILVIGAGGREHAISKKLLASPKVDTVYCAPGNPGMTKDGINC
                     VAISERDHSALIHFVKKEAIDWSIVGPEVPLLNGIVDDFMAEGLKIFGPTKAAALIEG
                     SKSFAKQLMDTYQIPTAKSRSFECYEKAAAYIKENGAPIVVKADGLAAGKGVVVATTV
                     KEALDAAEQMLNQHRFGDSSKKIVVEEFLAGEEFSLLAFVRNTKVYPMVISQDHKRAF
                     DNDKGPNTGGMGAYSPVPQISKKMIEKAVEEVLKPAALGMKELGRSFTGVLYAGLIAT
                     KEGPKVIEFNARFGDPETQVVLSRLKSDFAQVIDDLLENRTVELKWQQEGYNVGVVVA
                     AAGYPEEYETGMVLPDFLEEELSVYYAGVSSNNGKLVGAGGRLYLVEAYGETIKEAQK
                     KIYTALMDKTTDGTFYRTDIGEKAANSELIVK"
     gene            39125..40039
                     /locus_tag="LLC22_000525"
     CDS             39125..40039
                     /locus_tag="LLC22_000525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631494.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5433826.1"
                     /translation="MKKIQLGTSDQKAAAVILGCMRINNAEDPVKVIETAYENGIDFF
                     DHADIYGNGECEEIFADALAKTSIKREDLFIQTKCGIVPGVMFDFSKKHIIESVEKSL
                     TRLKMDYVDALLLHRPDTLVEPEEVAEAFDELERSGKVRYFGVSNQKPMQIELLKKYV
                     RQPLVANQLQFGLKHTGMIDQGIHVNMTDEASIDHDGSVLDYSRLHDMTIQAWSPYQY
                     GFFEGVFIGNEKFPELNQTLEELAAKYQTTPTGLASAWILRHPANMQVIAGTMNVGRI
                     KEIAQASEINMSREDWYELYRAAGNILP"
     gene            complement(40172..41737)
                     /locus_tag="LLC22_000526"
     CDS             complement(40172..41737)
                     /locus_tag="LLC22_000526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK5433827.1"
                     /translation="MYKVFIIEDEYLIRNNLREQITVLGSYYPITYVGEAGDGEMALS
                     SIIDLQPDIILTDIQMPFMDGLTFSKEARKLLPWTRLIFISGFDDFDYMKGAIQVQAD
                     DYLLKPIKSSELKQAIEKAVTALDLQQKETHTSSDLVFELKKNHFLNGLFKGSLTISE
                     TLKLAESFNRSLAGKKMTVLLAANQVSTDFEDYAHLSDYLKFLFRENQQVIFSAVSSR
                     FIKFLIVDSLEENVIETSYQVAQTLVHELEKGQKNNFSVAIGPVAERISELPASFEIT
                     QMILETASSLKEQIISYEDLIQEAKLPVDSVFYFDLSLDLSSLSKNEVSKYIEHLTKP
                     QGTPTRTRLYRLFVLTKLLQHVCLKEKKIPQEMVHCTSTSQRLAISADDSLYRSTVYM
                     FISFLTALPSQPSRNKYQPILNHALDFIKENFTDPDMSLTWVAQQVALSPSHFSTIFS
                     QSFNQTFIDYLTEQRIELAKKLLQQSDYRISDIAFEIGYNDPNYFSYLFKKKQGISPK
                     EYRTQLFLKNKNN"
     gene            complement(41730..43181)
                     /locus_tag="LLC22_000527"
     CDS             complement(41730..43181)
                     /locus_tag="LLC22_000527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5433828.1"
                     /translation="MTKNLSIKQIFAQANKAMLLFAVIPLLLSILLYSQQLLIYQQTI
                     ANIQKADAIALKVDQKVLESMWDLISGQVTVDEFNEENILEELRNDIREIKNNTNTLK
                     EISTLDVSLRTIDTLEDYQNELINNILAKDFMDTNEEIINQVDSVTQLLSDILQDFVR
                     VEIDLASKKNTTLVRSLILLTIVELGVLSTIFFYAKKNRRFLERKVQEPINQLIEMSE
                     QLSSGNLGFRLTLPETLELQTLTASMNKMAEDLNQSLRENALKQYHLAQSEVRVLQAQ
                     ITPHFIYNSLDAIISLIEQDCFEEALTMTHALSGFFRTSLSKGQDWIPLEKEISHIND
                     YLVILKIRYGHMLDYKIDIPETLFPVSILKMILQPLIENAVYHGTKYVRHKGFIRITT
                     CKIDEMIQFKVIDNGIGIPAEKLAEIRKELAKGIDSDFSIGYGLYNVNKRLLLYYGND
                     QKPITIDSKYREGTTVTLMIPLSPKTIGGNKHV"
     gene            complement(43195..44211)
                     /locus_tag="LLC22_000528"
     CDS             complement(43195..44211)
                     /locus_tag="LLC22_000528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5433829.1"
                     /translation="MKRVLFFLALVVIAYQMMGCTPNTKEAPDPLVVGFSQSGTESSW
                     RKKHTESIITALEKEDYQVLYRNGYMNQERQIQDIRTFIAYKVDMIIFTPLQESGWDS
                     VLKEAKRAGIPVILVDRHIQTNDPELFVTHIGPSFKAEGNRAGLFVSNHFTNSKKQEI
                     RILELAGSENSTPTKLRSEGFLESINRKPTLKKDGTIDHKPPMTIVHRIVGDFIRMKG
                     KDQMKRYLETNDLSEIDVLYSHSDEMTHGALAAIKETSIKPGEDLIIVTIDGQEDMIE
                     KLRSGIVNCVVECKPDVGWYVANTVTRYFGNIQTGKTLPKDIFISETVFSQQNIANIP
                     TRNY"
     gene            44431..45519
                     /locus_tag="LLC22_000529"
     CDS             44431..45519
                     /locus_tag="LLC22_000529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar-binding protein"
                     /protein_id="HBK5433830.1"
                     /translation="MKNKFRKIVGTIAILTASILLSACGNSGSADDSTGYVGIAMPTK
                     SAERWIADGNNMVSELEKLGYKTDLQYGEDKVENQVAQIENMITKGVDTLVIASIDGS
                     ALTDVLAKAKEADIKVIAYDRLLMNSENVDYYATFDNFGVGVSQAAYIEEHLGLKEGK
                     GPFTIELFGGSPDDNNALINYNGVMSVLQPYMDNGQLVVPSGQTSFSQIATLRWDGST
                     AQARMDNLLSANYTDQTLDAVLSPYDPISLGIISSLKGVGYGSESKPLPVITGQDATV
                     AGVKSIIAGEQTQTIFKDTRILAKNTIEMIKAISDGEEVPVNDTETYDNGVKTVPTYL
                     ANTVSVDKDNYQAELIDTDYYKESDLKN"
     gene            45573..47099
                     /locus_tag="LLC22_000530"
     CDS             45573..47099
                     /locus_tag="LLC22_000530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315151.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter ATP-binding protein"
                     /protein_id="HBK5433831.1"
                     /translation="MADCILKMADITKKFSGIRALDCVNLMIERGEIHALCGENGAGK
                     STLMNVLSGLYPYGSYDGEIFYDGKLCQFKDLKDSEEKGIVIIHQELALSPYLSIKEN
                     IFLGNEQAERGVIDWELTEKKTYELLNKVGLSIDPNLLVSQIGVGQQQLVEIAKALSK
                     SVRLLILDEPTAALNEEESANLLRLIRELKEQGVTSIIISHKLNEIVDIADRITILRD
                     GQTIETLENEMISEEHIIRGMVGRDLVDRYPERKPDIGEVYFKVEDWTVYHPLDHERI
                     INDHINLHLKKGEIVGIAGLMGAGRTEFAMSLFGHSYGSKISGRILKEGAEISVKTVP
                     SAIANGLAYVSEDRKSLGLNLLMDIRENVTLSSLDKISQKGVLDKEKEVTEAENFRKK
                     MRIKTNSIHQIVSSLSGGNQQKVVLSKWLMTQPDILFLDEPTRGIDVGAKYEIYTIIE
                     EMAANGKAVCLISSELPEILGMCDRIYTMNEGRITGEVSREDADQEVLMKLMTKEEVG
                     "
     gene            47101..48306
                     /locus_tag="LLC22_000531"
     CDS             47101..48306
                     /locus_tag="LLC22_000531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5433832.1"
                     /translation="MEQAKNLTDKKEKKLNLKSRAADLFGRYSMVIILAGLLIAFQLM
                     TDGIFWRPLNITNLVLQNSHILVLAAGMLLVVLLGHVDLSVGSVMAFVGAIAGMMMVN
                     RQMNPWMTVIACLAVGGLIGAWQGFWVAYAGIPAFIVTLAGLLMFRGLTQVVLGGQSL
                     APFPAVFQKMSTGYLPDLSEGSSLHFLTLILGMIITIVLVVGQWRTRNRRKNHLFEVE
                     SPTAFLVKAVFTAVVVLGITYIFASYQGYPIILIILGLIVAAYGFLTNKTVAGRQIYA
                     TGGNRKAAELSGIKTKRITFWVFVNMGVMAALAGLVLAARLNAATPQAGTSMELDAMA
                     AVYFGGASTSGGIGTIMGAIVGGLVMGVLNNGMSILGVGVDWQQAIKGLILLLAVVLD
                     LYNKKKRTT"
     gene            48563..49540
                     /gene="guaC"
                     /locus_tag="LLC22_000532"
     CDS             48563..49540
                     /gene="guaC"
                     /locus_tag="LLC22_000532"
                     /EC_number="1.7.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GMP reductase"
                     /protein_id="HBK5433833.1"
                     /translation="MKVFDYEDIQLIPNKCIVNSRSECDTTVTLGKHTFKMPVVPANM
                     QTIIDETIAEFLAENGYFYIMHRFDEAARIPFIKKMKKRGLITSISVGVKKEEYSFIE
                     KLAEESLNPDYITIDIAHGHANSVIDMIQHIKKYLPETFVIAGNVGTPEAVRELENAG
                     ADATKVGIGPGKVCITKIKTGFGTGGWQLAALRWCAKAARKPIIADGGIRTHGDIAKS
                     VRFGATMVMIGSLFAGHEESPGETKVENGIVYKEYFGSASEFQKGEKRNVEGKKIWIQ
                     HKGSLKDTLVEMQQDLQSSISYAGGRDLEAIRKVDYVIVKNSIFNGDTI"
     gene            49804..51228
                     /locus_tag="LLC22_000533"
     CDS             49804..51228
                     /locus_tag="LLC22_000533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PLP-dependent aminotransferase family protein"
                     /protein_id="HBK5433834.1"
                     /translation="MWEKVEKKQGPIYRQIMEQIMREIENGRINPGSQLESERKLGQL
                     FGVNRSTVVHALEELRELGVLTSKRGSGWFVNQTEWGKFAVPRIDWRQMISPRYEQTD
                     WYEQKIREAKQIQKTSFLDLYASEMPDELLPNFEFPSYSLEEILAEEKEMDLLGYTPL
                     RNKIKRYLESKFELAFSPNQLLVTGGGQQAIFLILQTILSAGEGIAVESPSFFYRLPL
                     FKASGTRLFGIPMDEEGIDLEKLKESIHKNKLKAVLINPNFQNPTGKVMSQKRREKLV
                     ELCRQYRLPIIEDDVFTDLSFLNQEEVLPIRTIDPDNVLYVGSLSRVLGKTTKIGWVI
                     GPETFISQLAQAQEMMEFSMNILTQITVANVFNEAIDLKMQDVRKKLKEKSRLISAWG
                     DSQSFFKLHSILGGYYAWITWDGKKLDPELAEKVVDMGLGIAPSLLFGQDINGIRINY
                     SRLDENQIPLFYSKMKILEKWLTE"
     gene            51689..52798
                     /gene="pdhA"
                     /locus_tag="LLC22_000534"
     CDS             51689..52798
                     /gene="pdhA"
                     /locus_tag="LLC22_000534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate dehydrogenase (acetyl-transferring) E1
                     component subunit alpha"
                     /protein_id="HBK5433835.1"
                     /translation="MANKKAPIDFQALLDEVNADFPVYQALDQDGNVVNKDLVPDLSD
                     DELVELMTHMVWSRVLDQRSTALNRQGRLGFFAPTAGQEASQLASAYAFDKEDVLLPG
                     YRDVPQLVKHGLPLSQAFLWSRGHAAGNSYPEELKALPPQIIIGAQYVQAAGVALGLK
                     KRNKKNVVFTYTGDGGSSQGDFYEAINFAGAYHANAVFYIQNNGYAISTPREKQTAAK
                     TLAQKAVAAGIPGIQVDGMDPLAVYTVSKMAREWAISGNGPVLIETLTYRYGPHTLSG
                     DDPTRYRTKDTDDDWQKKDPLIRFRKYLTEKGLWSEEKEEQVIEATKEEIKAAIAEAD
                     KVPKQKVSDFLKNMFEVSPQSIKEQIAIYEAKESK"
     gene            52801..53778
                     /locus_tag="LLC22_000535"
     CDS             52801..53778
                     /locus_tag="LLC22_000535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-ketoacid dehydrogenase subunit beta"
                     /protein_id="HBK5433836.1"
                     /translation="MAQKTMIQAITDALALELENDENVVVFGEDVGKNGGVFRATEGL
                     QEKFGEDRVFDTPLAESGIAGLSFGLALEGFRPVPEIQFFGFIFEAMDEVVAQMARTR
                     YRMSGTRNLPITIRSPFGGGVHTPELHSDNLEGLIAQSPGIRVVIPSNPYDAKGLLIS
                     SIRSNDPVVFLEHMKLYRSFREEVPDEAYEVPLDKAAVTREGTDVSIITYGAMVREAI
                     KAADNLAKENISVEIIDLRTVAPLDVETIIQSVEKTGRVVVVQEAQRQAGVAAQVVSE
                     ISERAILSLEAPIGRVSAPDTVFPFGQAENVWLPNAKDIEDKVKEIAEF"
     gene            53803..55446
                     /locus_tag="LLC22_000536"
     CDS             53803..55446
                     /locus_tag="LLC22_000536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyllysine-residue acetyltransferase"
                     /protein_id="HBK5433837.1"
                     /translation="MAYQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHEDNEGDSGVAAESQTPAKPAA
                     EPTVDTESAGSSSEGVFQFKLPDIGEGIAEGEIVKWFVKPGDTINEDDTLLEVQNDKS
                     VEEIPSPVTGTVKNVIVPEGTVANVGDVLVEIDAPGHNSAPSTSAPSAEAPKEKVETS
                     GSASVVEAADPNKRVLAMPSVRQFAREKDVDISQVTATGKGGRVTKEDIENFLAGGPS
                     SAPAKSEAPEAAAPKEAAPAAESKPAAPAKPFKSNLGDLEERVAMTPTRKAIAKAMVN
                     SKHTAPHVTLHDEVEVSKLWDNRKRFKEVAAANGTKLTFLPYVVKALTATVKKYPVLN
                     ASIDDANQEIVYKHYYNIGIATDTDHGLYVPNVKDADRKGMFAIADEINEKAKLAHDG
                     KLSAEDMRNGTITISNIGSVGGGWFTPVINYPEVAILGVGTIAQQPIVNAEGEIVVGR
                     VMKLSLSFDHRIVDGATAQQAMNNIKRLLADPELLMMEG"
     gene            55454..56860
                     /gene="lpdA"
                     /locus_tag="LLC22_000537"
     CDS             55454..56860
                     /gene="lpdA"
                     /locus_tag="LLC22_000537"
                     /EC_number="1.8.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrolipoyl dehydrogenase"
                     /protein_id="HBK5433838.1"
                     /translation="MVVGDFAVELDTVVIGAGPGGYVAAIRAAEMGQKVAIIEREYIG
                     GVCLNVGCIPSKALIAAGHHYQESLDSEMFGVTSENVKLDFAKTQEWKENKVVHTLTS
                     GVGFLLKKHKVETIEGEAFFVDDHTLRVIHPDSAQTYSFNNAIIATGSRPIEIPGFKF
                     GGRVLDSTGGLALKEVPKKFVIIGGGVIGAELGGAYANLGAEVTILEGSPQILPTYEK
                     DLVKLVEDDFKKKGVTVVTNAMAKEAVDNGDSVTVKYAVDGKEESVTADYVMVTVGRR
                     PNTDDMGLEQAGVEVGERGLITVDKQGRTNVPNIYAIGDIVPGAALAHKASYEAKIAA
                     EAISGKKVAVDYKAMPAVAFTDPELASVGMTIKEAKDAGIEAKAYKFPFSGNGRALSL
                     GKTEGFIRLVTTIEDNVLIGAQIGGVGASDMVSELALAIESGMNAEDIALTIHPHPSL
                     GEIVMDASELALGLPIHI"
     gene            57022..57297
                     /locus_tag="LLC22_000538"
     CDS             57022..57297
                     /locus_tag="LLC22_000538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UPF0223 family protein"
                     /protein_id="HBK5433839.1"
                     /translation="MQEYQYPLDLDWTTDEMVIVMKMWEDLERANEKGINNEAFLKTY
                     QQFKTVVKSIGEEKRLGREFEKASGYSLYRTVQQAKKNPNKTLRMNG"
     gene            57303..58070
                     /locus_tag="LLC22_000539"
     CDS             57303..58070
                     /locus_tag="LLC22_000539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="inositol monophosphatase family protein"
                     /protein_id="HBK5433840.1"
                     /translation="MEQMIDHIKSWLEEAGEKIKSSQQTLTISQKSNRTDLVTNVDRN
                     IQNFLIEKIHSFDPEAKILAEEEGCNQLSDLDGRVFIIDPIDGTLNFVIEGENFCIML
                     AVYESGVGKLGFIYDVMRNELFWGGKGIGVYKNDEPLPRPANKSLSEGLLGVNSYLFG
                     HNKYGIREIAESSMGTRMYGCAGLELVAILKGNHIAYISNLSPWDYAAGNVLLEEFGM
                     VTSGLFGTPLTFEKREYYLAGTSCAYAEIADLLKKEG"
     gene            58238..60067
                     /gene="typA"
                     /locus_tag="LLC22_000540"
     CDS             58238..60067
                     /gene="typA"
                     /locus_tag="LLC22_000540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translational GTPase TypA"
                     /protein_id="HBK5433841.1"
                     /translation="MNYRNDIRNVAIIAHVDHGKTTLVDELLKQSDTLDAHTQLQERA
                     MDSNALEKERGITILAKNTAVDYKGIRVNIMDTPGHADFGGEVERIMKMVDGVVLVVD
                     AYEGTMPQTRFVLKKALEQHITPIVVVNKIDKPSARPEHVVDEVLELFIELGADDDQL
                     DFPVIYASALNGTSSLSDDPADQEPTMAPIFDTIIEKIPAPVDNSDEPLQFQVSLLDY
                     NDYVGRIGIGRVFRGTIKVGDQVALIKLDGTVKKFRVTKLFGFFGLKRLEIQEAKAGD
                     LIAVSGMEDIFVGETVTPVDHQDALPILHIDEPTLQMTFLVNNSPFAGREGKFVTARK
                     IEERLMAELQTDVSLRVEPTNSPDAWTVSGRGELHLSILIENMRREGYELQVSRPEVI
                     EKEIDGVKCEPFERVQIDTPEEYMGSVIESLSLRKGEMQDMVHTGNGQIRLTFLTPAR
                     GLIGYSTEFLSMTRGYGIMNHTFDQYLPMLPGQIGGRHQGALVSIDTGKATTYSIMSI
                     EERGTVFVEPGTEVYEGMIIGENSRDNDLTVNITKAKQMTNVRSATKDQTSVIKKPKQ
                     LTLEESLEFLNDDEYCEVTPESIRLRKQILEKNAREKASKKKK"
     gene            60328..62100
                     /gene="recQ"
                     /locus_tag="LLC22_000541"
     CDS             60328..62100
                     /gene="recQ"
                     /locus_tag="LLC22_000541"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase RecQ"
                     /protein_id="HBK5433842.1"
                     /translation="MNDLLKQYFGYDEFRPGQKEIIQKVIDQENVLGIMPTGSGKSIC
                     YQLPALLLDGLTVVVSPLISLMKDQVDAANQLGIPATFINSSLDGYETARRFQEIDRQ
                     QYRLLYIAPERFIMPDFIQAMKRWNVRMIAIDEAHCISQWGHDFRPSYLQMANQLDQL
                     PNRPVIVALTATATVQVAADIKRLLKIPENNHIQTGFERENLRFQVIKDQKKEQYLIE
                     YLKINKNQSGIIYAATRKEVDRLYHLLKKFDFSVGRYHGGLNENERTEMQEAFLYDRL
                     QLIVATNAFGMGRNKSNVRFVIHYQIPGSLEAYYQEAGRAGRDGLSSEAILLFSPQDI
                     QVQKFFIQQSQREEGQKQKEYEKLKAMTEYVYIESCLQQYILNYFGETSSPCNRCGNC
                     LDDREIVEVTTEAQMVLSCLKRMGENYGKQMLMKVLAGSKEQKLQALGFGHLSTYGLM
                     KNQSQKETMQLIEYLISNGYLLTINGEYPVLKVTERGIQVLKGQESVYRKEPKKVQQL
                     SDEETDTLFEVLRELRTDLASEAGVPPYVVFSDSTLKEMSRIRPSSRLEMLQIKGVGQ
                     SKLDKYGEAFLSRIKNADSNVLDK"
     gene            62214..62516
                     /locus_tag="LLC22_000542"
     CDS             62214..62516
                     /locus_tag="LLC22_000542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlaN family protein"
                     /protein_id="HBK5433843.1"
                     /translation="MDSLSKKLAIQVLNDEAERIKRLIRNQNNSLCISQCKAFEEVVD
                     TQMYGFSRQVGFAVRIGVIGKNEGQLMLSELERELNQLYSEVYQEIYDKKEVGKEE"
     gene            62519..63682
                     /locus_tag="LLC22_000543"
     CDS             62519..63682
                     /locus_tag="LLC22_000543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBK5433844.1"
                     /translation="MPKKVKKRHLLDYSILIPYLILCVLGLIMVYSSTSYLLLENGQN
                     PSASVINQSIFWVLSLIAIALLYKMKTDVLKNQRLIMAAIAVLTILLLIVVFFGKEIN
                     GAKGWLQIAGFSIQPAEYLKIISIWYLSLTLSKRQNSVQKDFLGTVKRPLAMVIGLTA
                     LVAILPDFGNAAVIFLIILVLLLASGVNYVYTLIVGVGGFCLSTFTIWLINITNGKIL
                     PGRLQYIYNRFAIYQNPFSDELNKGHQLVNGYYAMFNGGLFGRGLGNSIQKKGFLQEA
                     QTDFIYAIVVEELGVIMGILILALLFFMIVRIVLVGIRSKDPFNSLLCIGIGAMFLIQ
                     VFVNLGGITGVIPLTGITFPFLSQGGSSLLMLSICVGFVLNISADEKRKSLGL"
     gene            63708..67136
                     /locus_tag="LLC22_000544"
     CDS             63708..67136
                     /locus_tag="LLC22_000544"
                     /EC_number="6.4.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate carboxylase"
                     /protein_id="HBK5433845.1"
                     /translation="MKKVLVANRGEIAVRVFRACTELGIKTVGIYAEEDEYSVHRFKA
                     DEAYLVGQGKKPIDAYLDIEGIISIAKECGADAIHPGYGLLSENLNFAQRCEEEGIIF
                     VGPKLHHLDIFGDKIKAKAAAIEAGIASIPGTDGPIASIDDALEFAKQYGYPIMIKAA
                     LGGGGRGMRVAHDEKSAREGYERAKSEAKAAFGSDEVYVEKYIANPKHIEVQILGDTH
                     GNVIHLFERDCSVQRRHQKVVEVAPCVSMNEQQRQKICQAAVQLMKYVGYVNAGTVEF
                     LVEGDDFYFIEVNPRVQVEHTITEMITDIDIVTTQLLIAQGLDLHKEIGLPQQEGIKL
                     NGSAIQCRITTEDPLNNFLPDTGKIDTYRSPGGFGVRLDVGNAYAGYVVTPYFDSLLV
                     KVCTHGATFETAIQKMERCLKEFRIRGVKTNIPFMLNVITHPEFQSGNAKTTFIDSTA
                     TLFEFPRLRDRGNKTMKYIGEITVNGFPGIESGEKPFYEEPRMPKDLITRTDYVTAKN
                     VLDAKGADALVEWIKGQENLLLTDTTFRDAHQSLLATRVRTKDFKQIARLTGEGLPEL
                     FSSEMWGGATFDVAYRFLNEDPWQRLRKIRSLMPNTLLQMLFRGSNAVGYSNYPDNVL
                     VEFVKEAAAQGIDVFRIFDSLNWTPQMEKSIQAVRDTGKIAEAAICYTGDINDPSRAK
                     YNVQYYKDMAKELEQLGAHIIAIKDMAGLLKPQAAYRLISELKETTDLPIHLHTHDTS
                     GNGIITYSAASKAGVDIVDVAMSAMSGNTSQPSMSSLYYALVNGPRLPEITIENAQKL
                     NHYWEDVRMYYKPFENGLNAPETEVYMHEMPGGQYSNLQQQAKAVGLGHRWDEIKQMY
                     HTVNLMFGDIVKVTPSSKVVGDMALFMVQNDLTEEDIYEKGETLSFPESVVTFFQGEL
                     GQPVGGFPKKLQKIILKGRPALNERPGLLAESVDFNEVKKELAEKIGYEPKQDEVLSY
                     LMYPQVFLDYQKAYNQFGDVTLLDTPTFFQGIRLGETINVQIERGKTLIIRLDEIGEP
                     DIEGNRVLFFNLNGQRREITIKDNSIISTVQTRLKAEPTNREQIGATMSGSVLDVLVK
                     KGDNVKKGDTLMITEAMKMETAIEARFDGEVAHVYVSSGDTISSGDLLIEVTEK"
     gene            67157..68281
                     /locus_tag="LLC22_000545"
     CDS             67157..68281
                     /locus_tag="LLC22_000545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433846.1"
                     /translation="MKRLGLFWLILLLVIVAFYMEPVLFPPKLEVKENSDQQISNQMT
                     TWKYQELKATGFSTYIGKPIDQLEKDFGQAYDRLTSGFGFETRYYENKASHLTFEANI
                     QDSRVTTVKVLQTGPADIAPFYLGMTMQDLTKITTIYTNFTFEYHDTEVGIELMEEDM
                     NYRPLIAFDNDTFAILFFDQTTNGLFSVVYLDKDSLLKLLPYQVFGEGLPHYQADKSA
                     DWESINRVKERKSTTLLNMLRREDELPIYNQTLAFQNHSQLLLHDFLTRPEEILSEER
                     MADWQKSLGSAQTTVKFSLTNDELEKLISKQKLENTSGLFIHPAIDATFSFLYWYSDP
                     YNHDRFMDPGTDSVGIAFSKENMLVLLQEENGESSDSSDR"
     gene            68271..68708
                     /locus_tag="LLC22_000546"
     CDS             68271..68708
                     /locus_tag="LLC22_000546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBK5433847.1"
                     /translation="MIVNEELFQLEDQCLQVAEMIKKSKTMASYLEHKQSMEESAKVC
                     QLKEAFLSKKEAFENVAAYGEYAPDYREKKRAVRKAKRQLDMDEHVAAFRYSETQLQS
                     LLDQIVQVLAEEVSNEIKVDAGSPFFETKKHFGCGGNCHAIRQ"
     gene            68692..69030
                     /locus_tag="LLC22_000547"
     CDS             68692..69030
                     /locus_tag="LLC22_000547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbG family protein"
                     /protein_id="HBK5433848.1"
                     /translation="MQLDNSEFEITKRRGLIVWVYSLKQLKNLKKFGLLHYVSRRMKY
                     VVLYLNEETLEETEERIRKLHFVRNVERSYRPDIEMNFAEKIGNKTVLKDEGFEIEEL
                     NTEIRLAEHL"
     gene            69149..69709
                     /gene="rsmD"
                     /locus_tag="LLC22_000548"
     CDS             69149..69709
                     /gene="rsmD"
                     /locus_tag="LLC22_000548"
                     /EC_number="2.1.1.171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(966)-N(2))-methyltransferase
                     RsmD"
                     /protein_id="HBK5433849.1"
                     /translation="MRIISGNYGGRRLKSLAGANTRPTTDKVKESIFNMIGPYFDGET
                     VLDLFAGSGGLAIEAVSRGCSHAVCVDKNYQALKIIKENIEITKEPEKFTTIKLDADK
                     AIERLAAEKQQFDYLFLDPPYAKQKIIDQIHKMEELGLFSKTAVIVCETDKTVELPET
                     VAGFHQIRKQIYGITAVTIYRKEGNQ"
     gene            69706..70197
                     /gene="coaD"
                     /locus_tag="LLC22_000549"
     CDS             69706..70197
                     /gene="coaD"
                     /locus_tag="LLC22_000549"
                     /EC_number="2.7.7.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantetheine-phosphate adenylyltransferase"
                     /protein_id="HBK5433850.1"
                     /translation="MKRALFPGSFDPFTKGHLDTVERAAKLFDEVVIGVFINTSKKSL
                     FPPEERMTLITKAVSHLPNVKVMHQENQLTVETAKEIGADALIRGIRSIKDFEYEREI
                     AQMNHHLYDELETVFLLAKPEYSHVSSSILKEVLHFGGDVSSYLPPVINEALAGKRES
                     NES"
     gene            70187..71230
                     /locus_tag="LLC22_000550"
     CDS             70187..71230
                     /locus_tag="LLC22_000550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374474.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PDZ domain-containing protein"
                     /protein_id="HBK5433851.1"
                     /translation="MKAKQWLKTVLIIIFGMLIIGFVVVPLPYYVESPGATIDLKELI
                     TVNDKEDKGSGSFSLTSVGIRQATGFLALKAKMTPFEELISEEELTGGATNEEYNQMQ
                     QYYMDSSQNAAIEQALKLADKPYKMEFKGVYVMSVEKTSNFFGKLSVGDTVTKVDGKS
                     FQSTEAFMDYVKSQKVGQTIEISYLHNGEEKTASGDLIELPTDKKAGIGITLTDHTEI
                     ESDTDVRINSGSIGGPSAGLMFTLEIYEQVTGKNLRHGKQIAGTGTINSEGEVGRIGG
                     IDKKVASADKAGVEIFFAPDDTISDDVKKEYPEIKTNYEEAKAAAKKLNSSMKIVPVK
                     TVQEALDYLEKMK"
     gene            71389..72117
                     /locus_tag="LLC22_000551"
     CDS             71389..72117
                     /locus_tag="LLC22_000551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016925838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-hairpin-helix domain-containing protein"
                     /protein_id="HBK5433852.1"
                     /translation="MKGVMNDFYWSFFEKRTMIEKISKKILASPKLIIWMSMIVLIFC
                     IASGFLLSNLLFYRETEETAAKEILSSFSSSGEDPSAEGNDVEEDARPKVMYTDIKGS
                     VKEPGIYSFSSEERVYDVLKRAGGLLEEADSDRINFSAKIEDQQVLYIPAVGEELPEH
                     LDQLASSEGKQPTADSEPPKININTATPSELQQIPGIGSVKAQEIIRFREENGSFQKV
                     EDLQEISGIGEKTVEKLKNFVTIK"
     gene            72233..72478
                     /locus_tag="LLC22_000552"
     CDS             72233..72478
                     /locus_tag="LLC22_000552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBK5433853.1"
                     /translation="MIVRKETLKKPMLNVYLQNKISGIHIMNTAVSGNNSQALRERFA
                     KDVLSYTADKVFILIGTNDLAEHKQLSKETYQKICSG"
     gene            72475..72693
                     /locus_tag="LLC22_000553"
     CDS             72475..72693
                     /locus_tag="LLC22_000553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase"
                     /protein_id="HBK5433854.1"
                     /translation="MIVQLKKDYSSDHAFFITPPAVDETKQKYRNNKLIKEYISVLTE
                     VAKRHDCEVSIFIRNFLNKWIRRIFIMG"
     gene            72829..73368
                     /locus_tag="LLC22_000554"
     CDS             72829..73368
                     /locus_tag="LLC22_000554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComE operon protein 2"
                     /protein_id="HBK5433855.1"
                     /translation="MLEKSSKACDTNKEKVTDKSHNERIPWDQYFMAQAVLLSLRSTC
                     TRLEVGATLVREKRIIAGGYNGAVSGDVHCIDEGCYVVDGHCLRTIHAEMNALLQCAK
                     LGIPTEGSEIYVTHFPCLACTKALLQAGVKGINYLHDYRNDPYAQALIEQLGVSVHQV
                     ALDSQHFSKLQNELTGKHV"
     gene            73361..75634
                     /locus_tag="LLC22_000555"
     CDS             73361..75634
                     /locus_tag="LLC22_000555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA internalization-related competence protein
                     ComEC/Rec2"
                     /protein_id="HBK5433856.1"
                     /translation="MSSVLERHVRNRLIFPAITSMIICLLYYTDNWGYRLLLAGIFLW
                     FSLKEGRFIAYLCILCSITVSISYRLQEYSFLEEKTTSAQITVFTDTIRANGNFLTME
                     GRLSENKQKLQLSYQVNTEAELKTWLNFRGKGIELTAEGEFISPAKKRNLYNFDQEAY
                     FRNHRISGRFQIQKIEQITMQNHWRNWLQRKRGSFISFVQSEFPQKTSVYINSLLWGY
                     KDAGFREPEEIFRESGLLHLFSLSGLHIQFYLGWLYYLFRRIGWPLHVSIIPLSLLTI
                     CYVSIAGSSISVLRASLLFLLRLLVKLLNKHYSTMDLFAVVFWLLLLFDPRFLFHAGG
                     QLSFFMSFLFILISFDGDWLKKTASHVLFTMITMPLIVWHFYEWPILGSLFTLLIAPV
                     FKFLFLPGVLFLTLFNRWLPETLLLLIEEGLILFERIIDFSSGSSLIIGRLPLVLSGM
                     YIFGLLICMDRLKEQPVKHLFYVGLFSFIFLTLPFLRFSSTIAFIDVGQGDSIFLQSP
                     FRKETILIDTGGQLHFEREKWAQGMIRPPAERNIVPYLKGQGISVIDKLILTHDDTDH
                     VGELPTLSQHFTIKKIYIGWGAGRNEPLQRHLSEAQKNGTEIIEIKHGDRISGYYDLY
                     VLTPFEKGEGRNEDSIGLWMEYNNRRFLFLGDLNQAMEKQLLLIYPNLKADVVKLGHH
                     GSRTSSNTDFLSHIEAKHGIISCGVNNRYGHPHSEVLETLEENQIKTWRTDQQGMITY
                     RWHPVFHPHGLVETMID"
     gene            75672..76718
                     /gene="holA"
                     /locus_tag="LLC22_000556"
     CDS             75672..76718
                     /gene="holA"
                     /locus_tag="LLC22_000556"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta"
                     /protein_id="HBK5433857.1"
                     /translation="MVSNLSIQAELQKIRKEKLASCYLILGTEKFLQDQVRTEIVKKI
                     QLEGEDDLNFLSFDMENASLDEVVAEAETLPFFGDQRLVFVENPYFLTGEKVNNGIEQ
                     NTDLLTAYLKEPLESTVLVFFAPYEKLDERKKVTKQLKKTAIIINVQQLNEKEVRQYL
                     MNTLENSSIKMERSAIDLFLRLTDLDLSKMMRELQKLVLYGQNQQQITVREVEELVPK
                     TLEHNIFDMTQYILKGKTEQALRLYEDLVMQGEETIKINAILLSQLRLFLQTKFLVKI
                     GYQQANIAETLKIHPYRVKLAMQEVKKFDEHLLVQLFDQLVEMDYQIKTGQIEKELSF
                     QLFVLRTGQLLRNR"
     gene            complement(76807..77061)
                     /locus_tag="LLC22_000557"
     CDS             complement(76807..77061)
                     /locus_tag="LLC22_000557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S20"
                     /protein_id="HBK5433858.1"
                     /translation="MPNIESAIKRVRTSENANVKNSSQTSAMRTAIKKFEDAVASGAD
                     NVDALYKEAVKAIDMAESKGLIHKNKANRDKSRLSKKIAK"
     gene            complement(77461..77730)
                     /locus_tag="LLC22_000558"
     CDS             complement(77461..77730)
                     /locus_tag="LLC22_000558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433859.1"
                     /translation="METFEGLLIDTYVLQEQPMMLTGINLQLEDRVINGLLKDRYLAK
                     YILRLPLNKYVLEVSGKWNRRNQLVIKKMLIKNIDEYIKIIGTPE"
     gene            complement(78200..78655)
                     /locus_tag="LLC22_000559"
     CDS             complement(78200..78655)
                     /locus_tag="LLC22_000559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF441 domain-containing protein"
                     /protein_id="HBK5433860.1"
                     /translation="MESWLFLGIILLVAILAKNQSLMIAAAFVLIMKLIPASRSFFPW
                     LQGKGINIGVTIITAAILIPIATGEIGLRDLLEAFKSPIGWVAVFCGGLVAVLSSKGV
                     GLIASDPQITVALVFGTILGVVFLRGIAAGPVIASGITYCILQVFALGK"
     gene            complement(78793..80721)
                     /locus_tag="LLC22_000560"
     CDS             complement(78793..80721)
                     /locus_tag="LLC22_000560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heavy metal translocating P-type ATPase"
                     /protein_id="HBK5433861.1"
                     /translation="MTNQKKAFAATIGCLLFMIFGFIFDRFSLTITPLFYISAIIIGG
                     YKQTSEGLKELWNDRTLNVDLLMALAAIGACLIGNYFEGAMLTFIFCLSGALEEYTTN
                     KSQKEITALMNLQPQKAQLLKENGQMQEVDVSQLKVDNLVFVAKGAAVPIDGFLESTQ
                     ATIDESALSGESVPVEKYLGDEMYAGTLNQGNPITIRVTKTSSETVFAKIIQLVEEAQ
                     NTPTQTASFIERIENNYVKLILLAVPLMILLPHFFLGWSWDESFYRGMVLLVVASPCA
                     LVASATPASLAALSNSAKNGILIKGGIHLEKLSELKAIAFDKTGTLTKGKPVVTDSFF
                     FDEKDLAQQLLVAMEQKTTHPLAHAILQYFDCTIPEEIQYLPIEEITGFGLQTTYLGA
                     QWKVGKHAYDPETMIISKEIAEMIERLENQGKTVIYLSKDQQLIAVLGLLDIPKANTQ
                     QVISYFKSQNIHTSMITGDHSGTAKAIAEQVGIEHYYASCTPEEKTQLVKKENELYQV
                     NAMVGDGVNDAPALAAASLGVAMGQGTDAAMDIADIVLMKSDLNKFVYSHRLSLKMRR
                     IIKQNIIFSILVILLLIASNFLQFLNLPLGVVGHEGSTILVILNGLRLLRPLPDLSDS
                     SKKCKSCPLYKARLSSVK"
     gene            complement(80918..81751)
                     /locus_tag="LLC22_000561"
     CDS             complement(80918..81751)
                     /locus_tag="LLC22_000561"
                     /EC_number="3.6.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl-diphosphate phosphatase"
                     /protein_id="HBK5433862.1"
                     /translation="MFFANIIKAVILGIIEGITEWLPISSTGHLILADEFIKLDASSQ
                     FMSMFNVVIQLGAILAVVVLYFHKLNPFSPSKSTVEKKDTWTLWFKVIVACIPAIIIG
                     LPLDDWLEANFHKFLPVAIVLIVYGIAFIIVEKRNKNKTPRWTSLNDFTYQAALLVGL
                     FQVLALVPGTSRSGATILGSILIGASRFVATEFSFFLGIPVMFGASGLKIVKYLAEGN
                     SFKMEETVVLLVGTFVSFVVSVLAIKFLLSYLKKNDFTAFGWYRIILGIILIGYWFIA
                     M"
     gene            complement(81943..82647)
                     /locus_tag="LLC22_000562"
     CDS             complement(81943..82647)
                     /locus_tag="LLC22_000562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5433863.1"
                     /translation="MTETTLYIVRHGKTMFNTIERVQGWCDTPLTKQGQEGIHYLGRG
                     LKNVDFSFAYSSDSGRAIETARIILGEHSKGKEIPYFIEKRIREWCFGSLEGGYDMEM
                     WGVIPRVLNFKTYDEMFTTEVSFEQIANAVYNLDTAGWAETYETLRDRVWTGFEDIAH
                     HCEKNGGGNVLVVSHGLTIAFLLNLIDPKQPVRAGLLNGSVTKVTYANGRFSIHGIND
                     TSYIDNGKTHSRDSFL"
     gene            complement(82670..83296)
                     /locus_tag="LLC22_000563"
     CDS             complement(82670..83296)
                     /locus_tag="LLC22_000563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK5433864.1"
                     /translation="MHIERLKTGMIEENCYLVYNEEALLIIDPGEDAERIKQEIKKTN
                     QQPVAILLTHTHYDHIGAVEPLRAYYQIPVYVSPLEQKWLGDPILNLSGLGRHDDIAD
                     VIVSPAEYEFEMKTYTLGNMSFRVVPTPGHSIGSVSFIFDDFVVSGDALFRGSIGRTD
                     LYTGNLEQLLHSIRTQLFVLPDEFAVYPGHGDATTIEQEKRTNPFFNR"
     gene            83622..85997
                     /locus_tag="LLC22_000564"
     CDS             83622..85997
                     /locus_tag="LLC22_000564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase"
                     /protein_id="HBK5433865.1"
                     /translation="MIKQSKISVRHLVEFILRRGSIDNRKKSNHTALEGARIHRKLQK
                     DAGENYEKEVFLKTTVQLDEYYLIVEGRADGIFKRDGIYYIDEIKTSEPRFEDLEPEQ
                     VELFFHQARVYAYIYSQEHDLQEINLQLTYFQTAEEVITRKVEHQTREQLETFFKKLT
                     EDYKEWLVFQENWRTVRNASLMALKFPHDEYRKGQRELAVAAYKTIRTKQKLFVEAPT
                     GTGKTISTLFPALKAVGEEEGEKIFYLTAKTITRQVAEDAMTALKDTGAEVKSVTLTA
                     KDKICFLDETTCNPDQCPYANGYYNRINEGLWDLLNHENQITREVIETYARKHTLCPF
                     ELSLDVSIWCDVIIGDYNYLFDPTVYLRRFFEDEKNEDYLFLIDEAHNLVNRSREMYS
                     AELSYEKTKRSKEAIPKEFKKLHRRFNKLLKEFDSIREIAKEDHWDYHHQKAPAESLV
                     KAGYQLSEKIKEWLAEFPEHPSQEQLLPYYFDLLHFLKVSEFYDDHYETTVEKTYRDL
                     IVKEFCIDPSLFLEQSLDKGKSSILFSASFSPLSYYQETLGGQKSLAYKLPSPFPEGN
                     QQVFIANYLETTYRKREHSLAKLVETIHAFADGKVGNYFVFFPSYQYLDLAVEAFRQQ
                     YPDSNVLIQETDMNEEERERFLTKFQTNPAETLIGFCVLGGIFSEGIDLRGDRLIGSM
                     IVGVGLPQMNHEQELIKSYYDEKEHLGFAYAYQLPGMNKVLQAGGRVIRGMADQGIVV
                     LADQRFSSFSYRRLFPQHWQTAREVRSVGELEEGIQRFWLSKEAVNQKNEE"
     gene            complement(86021..86512)
                     /locus_tag="LLC22_000565"
     CDS             complement(86021..86512)
                     /locus_tag="LLC22_000565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YajQ family cyclic di-GMP-binding protein"
                     /protein_id="HBK5433866.1"
                     /translation="MAKDASFDIVSEVNTEEVKNAIQQTTKELSNRFDFKDSTVEIKL
                     ENSNLVVLSDDDFKIEQIKDVLFGKLIKRNVPIKNIHFSESEHALGGKARQTADLVNG
                     IDRENAKKITTAIKNEKLKVKAQIQEDQIRVTGKNRDDLQAVIALLRKLDLPIELQFT
                     NYR"
     gene            86699..87619
                     /locus_tag="LLC22_000566"
     CDS             86699..87619
                     /locus_tag="LLC22_000566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5433867.1"
                     /translation="MTAYHKNERLKKIVVILITGLTAAVALNYFLIPANVFSAGMNGI
                     AQIISSLLYEWFHIKIDTGTFIFLLNIPVFVLGFLKVGKRATILSFVNVVCVSVMTML
                     LPVGQITDNILMNALVGGVLLGLGVGLSLKMGFTTGGMDIISLVLSQTTGKTVGNYML
                     ILNGIIVVIAGFFFNWESALYTIISIYAMTQVIDAIHTSHQKVTAMIVTVKPEEVTEE
                     LAKRMVRGMTLLPSVGGYSKKQGNMIMMVITRYEMYDLDQIVHEIDDDAFINILPTHS
                     VFGRFANENEQKMYRTTGVLPEIKNRSQKK"
     gene            87773..88117
                     /locus_tag="LLC22_000567"
     CDS             87773..88117
                     /locus_tag="LLC22_000567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-sulfur cluster assembly factor"
                     /protein_id="HBK5433868.1"
                     /translation="MSEANQERSGQEIELIKERILAALEMVIDPELGIDIVNLGLIYD
                     IEFNPENGETVIKMTLTTMGCPLADILTESIHDALKEVPEVTKAEVKLVWYPAWTTDK
                     MSRYARIALGIR"
     gene            complement(88307..88807)
                     /locus_tag="LLC22_000568"
     CDS             complement(88307..88807)
                     /locus_tag="LLC22_000568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5433869.1"
                     /translation="MKLIKLWEADLKKAYQLQTSFGPNESGFINNAYGYTFAEFLDYV
                     KKCEKTSLGIDLPESYVPATVFILESDEHEYVGIFNLRHKLNETLRNGAGHIGYGISP
                     NYRKKGYATQGLALVLQEAKKIGIDEALLSVNKKNLGSLKAQQKNGAAIYREDEKEYY
                     TKIKLM"
     gene            89335..89418
                     /locus_tag="LLC22_000569"
     tRNA            89335..89418
                     /locus_tag="LLC22_000569"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:89369..89371,aa:Leu,seq:cag)
     gene            complement(89742..>90176)
                     /locus_tag="LLC22_000570"
     CDS             complement(89742..>90176)
                     /locus_tag="LLC22_000570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBK5433870.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEPVQAEQPVVQET
                     VQTETQAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQL
                     DSSYLNGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT        29249 a        15582 c        19332 g        26013 t
ORIGIN      
        1 gattttactc gtttttcgat taattgtttt aacacttgca agtttctacg agtagcttgt
       61 ttccgacctt catatactca cctcaggctg tttacatgat tgtacgttct ttttgtaaag
      121 gatacagtga tatgtatata atggcataaa gaaacgttca aacaaaaaaa ctcgtgaagc
      181 aaaattaact tcacgagttg tagtgcagat gatgggactc gaacccacac gagctaacgc
      241 tcacatgacc ctcaatcatg cttgtctgcc aattccaaca catctgcgta ataataacac
      301 actaatgata gcgaggtttt acatagttgt caagctcaaa aatgggagga cttattaaga
      361 tggagaaata tgacggagaa ttttcaggac tgggaatgat cttaggtgta ttgattggac
      421 ttgcattcgg acgttttttg cttggtttta tgctaggaat catttgtgga atcgcaatgg
      481 attgggcagc gaatctatgg aatgactatc atgacaatta agttctcaac gcttgtttgt
      541 gtttttttaa tacttacgtt tttcctaaat aagtggcaaa attttctagg atggagtatg
      601 atattgaaat agtaaataac aaaaaatttg gaaagttcta actttttgaa atgagggatt
      661 ggctaagtga tgagagaatt tgaaaaatcc aacaaattag aaggtgtcag ttacgatgtt
      721 cgcggtcccg ttctagaaga agcggagcgg atgcaagaag agggcattag tattttaaaa
      781 ttgaacacgg gaaatcccgc accttttgga tttgaagcac caaacgaagt cattcgtgat
      841 ttgatcatga atgcccgtga ctcagaaggc tactcagatt ccaaggggat cttttctgct
      901 agaaaagcaa ttgagcaata ttgccaactg aaacattttc cgaatgtgac gatcaatgat
      961 atctacaccg gcaacggagt gagcgaattg atcacgatgt gtatgcaggg gttgctggac
     1021 aatggagatg aagtactggt tccaatgccg gactatccgt tgtggacggc ttctattgca
     1081 ttagctggag gcacacctgt tcattatatt tgcgatgaag aggcagaatg gtatcctgat
     1141 attgatgata tcaaatcaaa aataacgagt cggacaaaag ctattgttat cattaatcct
     1201 aataatccta ctggggcact ttatccaaaa gaattattag aagaaatcgt tgaagtagct
     1261 cgacaaaata acctgattat ttattccgac gaaatctatg atcgcttagt gatggatggt
     1321 ctagaacata ttccgattgc tacattagcg cctgatttgt tcgttgttac gctgaacggt
     1381 ctatccaaat ctcatcgtgt agcaggattt cgagtaggct ggatggtcct aagtggagat
     1441 aagtcacacg tcaaaggcta tatagaaggg ctgaatatgt tgtcctccat gcgtttgtgt
     1501 tccaatgtat tgtctcagca aattatccaa accgcgctag gcggttatca aagtgtcgat
     1561 gagctgctcc tgccaggcgg aaggatctat gaacaaagag aatatatcta taatgcaatc
     1621 aatgatattc ctggtctttc agccgtaaaa ccaaaagctg ctttttatat attcccaaaa
     1681 attgatacaa agcgattcaa tattttggat gatgaaaaat tcgttttgga ctttttacat
     1741 gaacatcata ttctacttgt acatggtggt ggatttaatt ggaaccagcc agatcatttt
     1801 cgaatcgttt atcttcctaa aatggatgat ttgaaacaaa cagctaagaa aatgagagaa
     1861 ttcctagcaa cctatcgcca aaaatgattt taaaaaccaa atttttcagt aggagggcca
     1921 cagacaaaca cactgaggct ctctttctag tggagttttc ttaaataact aaagtatatt
     1981 atttagttgc aagtcttttc ttgaagtttg cgacttccta aagtaaaata cgaatagaat
     2041 gcgaatacgc atattttggg gaggatactt atggaaacgt taatcgagtc ctttggaacg
     2101 atcattaaag agattcgaaa agaacaaaaa atgacgcaaa aaatgctttc gcatgatatt
     2161 tgttcacaaa gtgtattaag tcggatcgaa aataatgagg aactgccgaa tgtattggtg
     2221 atgatgcaga tttgtcaacg gctaggggta acgattgatc atgtgatgaa tctctctcga
     2281 aaaactactc ggacaaacga taaattattt gaactgttgg atagttgttt ccaaaaacgt
     2341 gattatcgga agttagaaca agtactaaaa tcttctgata tttctgaaaa tctgtatcaa
     2401 gcaactgact ttcaacgcta ttattattat ctcggtgttt gcgaattcac gttgcgtcaa
     2461 aatatctctc agtcccttta ttatttgaaa gaagcattaa gctactctag ccaaaaagaa
     2521 agaatccatg tttctgacac agaaatacaa ctgattagtt gtatcggaaa aatatatggt
     2581 gtggcaggaa aaacggctga agcacgctac tatttgagtc gaagcatcca actgctgcat
     2641 caatcagctg atgaacgatc aaaaagtgaa ttttcgcaaa ttttttataa ttatggaaat
     2701 ttcttattcc atcaaaatga aatcgacgaa gcgttagaac aggtgaatca aggaatctat
     2761 tgggctcaag agaagaatag ctactattac ctcaatgatt tatttgtgct taaaagctta
     2821 atatacaagc gtaaagaaga accagaaaga gcagcattct atgaaggctt agcacaagct
     2881 gtgaaacaaa tttcaaaaaa tttgtaaatg gtgtagacca ttcttgactt cttctctaaa
     2941 taagagtact ttagaggtag aaaaacaaag ggagagaata gaatgagaac ttttatctat
     3001 gctgacaaat tctttttagc gtcaggtgtc aaacatgcag gctatcttga aattaccgat
     3061 ggactttttg gtgaatacac caaagaacta cctgagggag aagtcaacat cattgaccaa
     3121 agcggcaaat ggattgctcc tggtttggta gatacacata ttcacggcta tatgaatcat
     3181 gatgtaatgg ataatgatgc agaaggcatc aaagtgatgt ctgaaggtct gttatcttgt
     3241 ggagtgactt catttttacc aacaacattg acgtcaagca aagaacgttt aaaagatgta
     3301 gctgagacaa tcggcaaaat gtatcaggaa gcaccaggag ctaaaatcaa aggaatctat
     3361 tttgaaggtc ctttcttcac agaagaacac aaaggggcac aaaacccaag ttatttcggg
     3421 gatcctgatt tggatacttt ccatgaatgg caagaagctt caggtggttt aatcaaaaaa
     3481 attgctttag caccggaacg tcaaggtgta gaagagtttg tcaaacaagt gactgaagaa
     3541 ggagtagttg tttctctagg acacagtaat gctacactag aagaagcgca aaaagctgtt
     3601 gaagcaggcg caagtgtatt tgtccatgct ttcaatggta tgcgtggatt gaatcatcgc
     3661 gaaccaggta tggtgggtgc gttattatct ttagaacatg tcttttctga attgatttgt
     3721 gatggccatc atgtacatcc aaatgctgcg ggaatcctaa tggaaaaagc aggacatgat
     3781 catgtcgcat taattacaga ctgtatgatg gccggtggga tgcctgatgg aaattacaat
     3841 ttaggcgaat ttccagtagt agtaaaagaa ggaacagcac gtctagaatc tggcaactta
     3901 gctggaagta tattgaaatt gaaagaagca attaaaaatg ttgtagactg gggattagca
     3961 acaccagaac aagcagtcat gatggctagt ctgattccag caatcagctg taaaatcgat
     4021 gatacatgtg gaaaaatcgc tcaaggacgc gatgcagact ttatcgtatt gaaccctgat
     4081 atgacattgg aagcaactta tctagatggc gtggaacgtt tccacgcata atataattta
     4141 agttaacctt aaaactaaac ttcttaagtt tggttttaag gttttttttg tgttctagta
     4201 aaaatcactt tacataagtt tcaaaagttt ctttaatttc ctattgttca ataagtaaca
     4261 atgtaaagat aaaattaaaa atgttaatac gtattagcaa aataaaagct ttttttattg
     4321 tgaataaatg aacataatta ggaggagaaa gatgaactta tttgacattt ttcgatcgac
     4381 tttgacagat atgtcgattg tcagtgcaat cacttcaaca gtttttatta tattattagg
     4441 gtttgtttgt agaaaaaagg ggattttttc tgaatctgtt ggaaaaattc tatcgaaagt
     4501 cgtcttaaca gtggctttgc cagcactggc atttcgagct ttcatgcaag atatcaatac
     4561 agaattactg atgcaaggaa tcaatgtctt gatttgggga ttagttattt atattattct
     4621 tattctagtt tcaaaacctt ttttcttaag ctataaaggg gataagcaaa caacgttgcg
     4681 tgtcctgacg atctttggtt ctacgacctt tttcggaacg cctatcgtca gtgcgattta
     4741 tggtcctgtc ggcgtgatgt attcctcaat tttcaatatt ggctaccgaa tctttttgta
     4801 ttcttatgga tacataaaaa tgagtggctt gaagatggaa gctaaaaata tcaaagcgat
     4861 gttcgtcaat ccaatcatta tcgctacttt tgccggcctt ttcatttggc tgttccaagg
     4921 gtatctgcca caagtgtcag ttacaggtgc agaaggagag ataagccaag tagcgttttt
     4981 gcgaattgac cagactgcac cgtggctatt tcagccgatg gattatttag ctggtttaag
     5041 ttcaccattg gcgtggctag caatcggcgc aacattaggt gaagtaagct tcaaaaaagc
     5101 tgcatctgaa aaaacttcat ggtattacag tctagtcaaa gtggtatttg tacctgcatt
     5161 gaatatcgtg attctagcag ttttgacggc aacgaatatt ctaccagtca attttgaagc
     5221 actggcaaca atcgttatca tgatggctac accagctgca acagtggcag cagcctatgc
     5281 tatcagtttt gatagggagg cacttttagc ctccaatgca tccttactgt caactatttt
     5341 tgctgtggta ctgacacctg tatggatcgt tgtattacaa atgattcatg gcataggttt
     5401 attttcataa gaaatggagg aagaaagtat gagaatcgca tgttacggtg ttcgtccgaa
     5461 cgagatagat ttttttgaaa aattgaatat ttaccattat gatctcagtc tttatgaaga
     5521 actgttgaca catgacaata tcgtgtcagc aaaggaccat gatgctgtat tgttgagggg
     5581 aaattgtata gcagatgaga ccaatcttgc aaaaatgcag gaatatggga ttcgttatgt
     5641 ttttacacgg actgtgggag tcaatcatat cgatctacaa gcggcagctg attttggtat
     5701 gacagtagcc cgtgtaccat cgtattcgcc aaatgcgata gcagagttat ctttgacttt
     5761 tgccatgatg cttttgagaa atactgcgta tacgacgatc cgaacatctt tcaaagattt
     5821 tcgagtggat gagcaaatgt ttagtcgtga aatcagaaat tgcacagtag ggatcatagg
     5881 aacaggcagg atagggttga cggaagctgt tttgtttaag ggactaggag ccaaagtgat
     5941 cggctacgat attcatcaga cagaagctgc taaaaaagta ttgacgttcc actcgcttga
     6001 agagttatta gccaaaagcg atattgtcag tattcatgta cctcatatcc caggtgaaaa
     6061 cgatcaaatg atcaatgaag gatttttagc tcaaatgaaa aaaggtagca tcttgattaa
     6121 tacagcccgt ggagagcttc aagataatga agctatttta agagctttga aaagcaatca
     6181 tttagctggt tttgcaaccg atgtttttgc aaatgaaaca gaggtttttt tccgatcctt
     6241 caagccatgg gagacgattc cagaccctgc tatccagcaa ttagtagaaa tgtaccctag
     6301 agttcttgta accccgcatg taggttcaaa tacagatgag gcattatcaa atatgatttc
     6361 gacaagtttc gagaactttc gtgaaataat agaaactgga aaaacgaaaa atgaggtatc
     6421 tcttcctaaa gcccgtcaat taagataaga aaacatggat attcgtcaat aaaatgttta
     6481 aaaatagtcc aagtaaacag ttgttacttc tgtatacttg gactattttg tatgggataa
     6541 ttcgatgact caacagtaat ctgtgagctt tttccgccca ttctttgtca attcataaca
     6601 ggttagcggc cggccgattt ccaaatattt gattctttcg ttcaatatat cttgttctac
     6661 taaaaaattc aaatatttct tgacggatat acgtgacagt gagctttttt gagccagttc
     6721 ttttgttgaa aaaatagtat cttcttttag aataaatgca cttatttttt ttaaagtcag
     6781 ttttgacaga cctttaggca aatcgatgaa tgatggtatt tcgtgaatgg gagtggtgtg
     6841 gttgaatact tgatcgatca atttctgatc ggctttttca gtcgtttgga ttgtctgaga
     6901 gaaagcaaga tacttttcga tcgccagctg aaaacgttgc aaagtgaacg gtttgatcaa
     6961 ataatctaag gcaccgtagc ggatcacatt ctttatggtt tcgatatcat ctgcagcagt
     7021 gatcaaaatc actgggatat catttccttg ctgtctaagc caagataaaa aatggatacc
     7081 actttcgcca ggcatgtata catcaagcag cagcagatct gcgttttttt gtctgaaata
     7141 tttttttcct tcttctacat ttctgaaact ttcgattacg ttcatattag ggatgctttc
     7201 cacaaaagta cgattcaatt ctgcaaccat tggatcatct tcgattatca ggacatttgt
     7261 catcattttg atcttccttt tttggtaatt ctagatagac gattgtaccg ccatttgttt
     7321 gtttggaaaa ttctaaaaat ccaccgtggc gtttgacgat tgaatggatg agattcaatc
     7381 caaacccacg attgattccc ttcgtcgaaa aacctagcgt aaatattttt tctgagattt
     7441 cttctgatat cccgacaccg tcatcgcaga cggtcacgat gaatacttca gcttctgtgt
     7501 catagtttaa atgaatccgg acctgtccgt ttctttcatg tttttgtagc acggcttctt
     7561 ttgcattatc aagtaagttc cctaacactt gcaaaagtga atggatggag tcatccatct
     7621 ccattttagg gataaaagaa tcgctttcta acagcatttc aacagattgt tctttggctt
     7681 cgtttatttt gcctaataaa aaaccggcaa ttgcaggtac tttgatcaga cttgagactt
     7741 ggccaatctc ttttttataa ttttgattta gctgctggat aaaatgggtg acttcttcat
     7801 acttcttcaa atcaatcaaa ccagaaatga catgaagttt attcatgaat tcatgggttt
     7861 gagctctcat ggagtttata tattgtttcg tccccccaag ctcctccatt aatttcatta
     7921 cttctgatcg atttcgtaaa gttgcgactg ctcctaaaaa acggtcattg ctaaaaagag
     7981 gtgtaacgct agaaatagtt tctatcccat ttaaatacat ggattgagtc cgaacggtcg
     8041 tttgatgctc aatcgtctct ttaaacaaaa cgtcatatag attatcactg atttttttcc
     8101 tacttcgaaa tccaatagct gctctgtttg gtagaaaatg ttttttgcag gtgtattgat
     8161 caagaggata gttttatcag aagagatggc taagattcct tcatctactt cattttcgat
     8221 aatcgttttt tcacttaact gttctgctat ttcttgtggt tcaagtccaa gcagtacttt
     8281 tttcattttt tgggcaagaa aaacggcgcc tatgatgcct acgctaagtc caataatcaa
     8341 tgaaaaaaca atcatttttt gtccatcttt gacttgattg tcaatcgtgt tgtttgttaa
     8401 gccaacacaa actgcaccaa taatctcttg atcataataa atagggacga aatagcggaa
     8461 gccgaaccct aacattcctt ctttttcaga gaaaaattct tgtcctccaa tcactttttt
     8521 cacatcttca tgacttgaga aaggaagacc gatgtaactt gggtctgcgt gagaatatcg
     8581 aatgccttca gggtccatga caacgataaa atctaaattc gatgcaatca tgatttcatt
     8641 tgttattcct tgaatcgcat gtgtcgggtc accagtctgc agcttttttt ggatgagttt
     8701 atcattggca acgattttag caatgctaga gattttatct gacacactag atcggttcat
     8761 cgaaagaata aaattcctga tcaatatggc agaaacaatc aaagaaacga atgtggagaa
     8821 acaaacgaca aggatgatcg tgttctggag ctttaatggt tttttcttaa aaaaaggaaa
     8881 cataggctac ctcgaaagaa tttattgtga aaattttaac atgaaaacaa aaatttaaca
     8941 aattgtcaac gataaacaca accttcctat aaaaaacacc actgagtcgg taaaagaagc
     9001 tatacagaat tttcaaacat tggtatgata gacgtagaaa tggaaggagg cgtgtatatg
     9061 atagggggaa tcgcacttga gacgatttat tggtatacat tgctgatttg tgcaggattg
     9121 gcagtcctat tgattatttt tggagatgta ttcgattttg atggcccgct tgatccgatg
     9181 cttattatcc cttggttaac tttcacaagc ttatttggtt ttctaggtga gcgtttaaca
     9241 gatcaatcat ctttattttt atttattgct agtggaggca tatcgatagt gttggtattt
     9301 ttgcttaatt tctatatatt gatgccgatg aaacatgccg aatcaacgat gtcgtcttct
     9361 gaaaaaactc tggaaggaca agtagctgtt gtgatcacac cgatccctgt acgaggtatg
     9421 ggagaaattc agttgaaaag tgttaccggt tccattagtc gtccagcttg tttttacagc
     9481 ccccaagaac agacagctga gcggggaacg aaagtattga tcattgagat caaggaaaga
     9541 atctgttatg tcatgcctta tgaaagcatg ataaaagctt aaaggagcgt gtgttaaatg
     9601 gaaataccag ttgtttttat cgcgatcgca atcgcagctt tgattttact gatgttgctg
     9661 atcgtctttg tagcgaagta ccagacagca aaaccggatg aagcgttgat catcagtgga
     9721 agttatttag gaagcaaaaa tgtgcacatt gatgaaagca ataacaaaat caaaattgtg
     9781 cgtggaggtg gcgcattcgt cttgccagtt tttcaacgtt cgaatcggat cagtctatta
     9841 tcgagtaaat tggacgtctc cacccctgaa gtgtatacgg aacaaggcgt accggtgatg
     9901 tgtgatggta cttcgatcat caaaatcggt tcatctgtag aagagattgc tacagcagca
     9961 gaacagtttt taggcaagac aagagaagaa ctggaaaatg aagcaagaga agtattagaa
    10021 ggacacttgc gctcgattct tggttctatg actgtagaag aaatctatca aaatcgcgat
    10081 aagttcagtc aaagcgtaca agaagtcgct tctgtagacc ttgcaaaaat ggggttgatc
    10141 atcgtttctt tcactatcaa agaggtcaga gacaaaaacg gttatcttga ctctttaggg
    10201 aaaccaagaa tcgcccaagt caaaagagat gcagatatag cagaagcgga agctctaaaa
    10261 gaaacgcgta tcaaaaaagc tcaagcagaa aaagaatcac aagcagctga attacagcga
    10321 caaacagaga tcgcagaatc attaaaagaa aaagaactga aattagcaac ctacaaacaa
    10381 gaacaagatg ttgctaaagc aaaagcagac caagcctaca atttagaaag tgcccgagca
    10441 caacaacaag taatcgaaca ggaaatgcag attaaaatcg tagaacgtca aaaacaaatc
    10501 gaactggaag aaaaagaaat cacacgtcgt gaaaagcaat atgattcgga agtgaagaaa
    10561 aaagcagatg ccgatcggta cgctaaagaa caagaagcac aagctcaaaa agtcaaagaa
    10621 gttactgaag ccgaagcaga acgattccgt gtggaagcac tggcagaagc ggaagccaat
    10681 aagacacgtt tagctggaca agcagaagcc gaagcagcac tagcaaaagg aaaagcagaa
    10741 gccgaagcaa aacaaaagat cgccaatgcc ttcaaggaat atggcgaagc agctgtcttg
    10801 agtatggtta tcgatatgct accgcaattg atgcgcgaag cagcacagcc gctaggaaat
    10861 atcgaaaaaa tctctgttgt cgatacagga agcagttcag gagaaaccag tggagcgaac
    10921 cgagtgacaa attatgccac aaatttgctt tcttctactc aagaaacact aaaagcgaca
    10981 acaggacttg acttgaagga aatcgtagag aatttgtcga cacgtgggac tactagccaa
    11041 gtaaatatgt atgaagcgcc aaaagaggca gaacaaaact cgatgaagga agaataaagt
    11101 agtacacttc accgttcaat caaaaatgga ggaagacttt ttaaagttct tctctccatt
    11161 tttttatttt attgcaaaag aaaattagtc ctcgctattt ttcttttgtt tttggatctt
    11221 agcttctatc tcttgtaaat ttgttcttag caatcgttct ttcttttgga gttcgaccaa
    11281 atcttctgat agttcttcct tcttttctgt ttcaggagga cgaagaaaga aattgatacc
    11341 gattgcaatg aatgtcccta taaaagtatc tagtacacgt tggatagcat acaaagcgga
    11401 ttcgccttga gggatgctca acgcaatcag caacaacgta gctattgcgg aaatgatacc
    11461 ggaattattg ttaataccat ctgacacgac gatcacaata ataactagaa taggaagcaa
    11521 gatcaattct accaaaaaat cattgtgaaa atagcttttg acaaaaaaat aaatgatagc
    11581 taatgtacca cctaatgtat tgccgatgat cctagacttt ccaaaagaaa cggttgtagt
    11641 caagtcctga cgcaaagaaa aaacagcaga taatgcagca atcatcggga ttcctcgttg
    11701 agtcaaatga aaaaacaaga tacataaaaa aacagctaag gcacttttga tcgtacgcat
    11761 acctagtcga aaacggccaa attgcataga gattctcctt tttggtcttt ttactatcat
    11821 acctaaactt ttgtctgata gctagttttt cattattcaa gtataattaa aataaaaaag
    11881 ggggaagtaa atgcgtatag gaatgcgaac agtcaaaaca gtgatcagtg tcttcttttc
    11941 gatggtcaca gcgggtagct tatcgctgtt gtattggcca gctgcaggga tcattgcatt
    12001 attaagtgta ggaaatacca agcgctctac attgcgtacg ggcatgaatc gaatcgcagc
    12061 ctttatatta gctacggcaa cagcactgtt cagttttttt gctgttgggt atactatttt
    12121 tggcttcagt ctttttttat tcctgttcat cccgcttgcc tctcgcttca aattaaccga
    12181 agggatagta gtaaattcgg ttttggtcac tcattattta gtggaggaaa acatgtcttg
    12241 gcagctgatc ggcaatgaag cgggattaat ggcgattgga ttagtatttg ctttgcttgc
    12301 aaatgtttac atgccagatc gtacgaagca gctgaaggaa aaccaaatac agatcgaaaa
    12361 agaatttcga aatattttga gacaaatggc agaatttctt ttatcagaaa ataaagaaga
    12421 tgtgcagatc aaatgcgaac atttactgac attcattcgc gaaagccaag aagatgccag
    12481 agaacatcaa gaaaactact ggctcagaca gccgctatac tacgaaactt acttctctat
    12541 gagaagagca caggccaatg tgattaaaga catgctggaa aatctagaga gaatccagca
    12601 accagcttat tatggaaaac atatctatgg tttattgatt tatactgcag aaacattttc
    12661 agagtcaaat gatggcagac aaattttaac acgtattgaa gaagtttatg tattgtatcg
    12721 gcaaatgcct ctgccgacta gtcgccctga attcgaggat cgagcagaat tgttccagtt
    12781 tttgcagtct tttaaaagtt ttattgaaat caaggcagaa ttctcccaac aaaaaatcca
    12841 aaaatagagg ttgtgaattc agctaatatt caggtcaaaa agctgatttc acaacctctt
    12901 ctttaaacgg tgttctcctg tcaactcctc ggtcacaagt cacaatattc aacaaacatg
    12961 agaagctgtt ttttgaaatt gctccttgtg actcggagct gaacggtagg ctcacaacct
    13021 ctttcttaaa cggtgttcaa aagctttcct ctgcggtaat aagtccagcc aaacgaaaaa
    13081 taggaggagc tatttttgtt tggctgttct tattacttga tgcagaacag ctttttcaca
    13141 accttttaaa attacatatt tttccataga acttgcattt gatccaagat ttcgatgaca
    13201 tcttttgtca agaagagaga gcgattgggc aagtcacctt caatcatgtg taccatattc
    13261 tttatttcgt aattcattgc ttcagatgta ttcccgcttt cgatgaattc ctttgtacca
    13321 tctgtaaata agatctccgc acgatcagca cgcgggtaat cagcaatcgt cacataaccg
    13381 ttctcaaagg caacgatacc gacttttggc atttttgcct gaaaagtcaa gctgacagca
    13441 gcaagttcat tttctttgtt acgcaagata gtgacggatt gttcgtccac gcctgtttca
    13501 aaaggaacca ttgtagaggc aactacttca ggttgagagc tcaaaaagaa acgagcgaaa
    13561 gatacagcat acgtaccgat atccaacaga gctcctccag ctaattctgg attgaagaac
    13621 cggtttttag ggtctggttc tttgtaactg ccgaaaggtg cttggatcat ttttaaagcc
    13681 cccagttttc ctgtatccat tattgagcgt aactgctgat aaagtggcat gttgaagatt
    13741 gtcatcgctt ctgctaagat caaattcttt tcttctgcta agcgcatagc gtcagccagt
    13801 tcttttttat tcatcgtgat ggctttttca catagaacgt gtttgcctgc ttccaatgct
    13861 gccaagatat ggtcgatatg ctgtctattt ggtacagcaa tgtacacgat gtcgatttca
    13921 gcatcgtcta acatttcttg atagcttccg taagcttttg gaatattgta acggtgagcg
    13981 aagttttccg ctttttctga agttctggaa gcaactgctg ttagttcgct cgtctcttga
    14041 ttgaagcttt cggcaaactc atgtgcgatg gtaccaagac caacgattcc ccattgatat
    14101 tttttcatct gaaaacgctc cttcatagtt ggattgagtt tcttgtctgt ctattattat
    14161 aacaaaaatc acgaagaata aagaggagag gacttgaaac attaaaaaaa atgaaagcag
    14221 cgatttaaga ggtgcttttt gatcaaaact taagtagaat agttaaaagg aggggataaa
    14281 cgtgcatcaa gtatatattg atcttattat gagtgtatta ttagaacagt ttgaaactga
    14341 aaaaaatttt ttagatgaat acttgctgat cagtccagaa caatggcaaa aatggaaaga
    14401 tggcgagaaa aatctgccat ctgaagcgat gcagaaagta aaaaatcttt tcactgatta
    14461 tgaatggatg ctaacgcaaa agattttgcg tcaaacgatt atttttcccg aaaaacgaaa
    14521 cgttgccgtt gcagagtaca agcaaatcaa aacacgcatc gcgcaaaaat ggcttagcag
    14581 caaagcagca aaagtcgagc tgatcccttt gaaaaataat cagcaggctg gtagatacct
    14641 tgacttgaaa gtaagtattc aatatgatga atggggctat gatgatattt tgaattttcg
    14701 tctgccagca gatgttcaaa aacagatcga aggagaaaaa atcgaacttc tcgattgggt
    14761 gaatgaaaat ctggaagaaa cttacgttca tgaggcgaat ggggaacgtg aagaacaacg
    14821 aaaggatttt tcaagtgaat aaatttttag gatttggagc agttgtgatt atgatcgcag
    14881 caatgggcta tgttattttt agcgatgatg attcgcatgt tcaagccggc aatcaagcag
    14941 tcgaacgaac aagcaccaaa acaactgcta gtaaagaaaa gaacagtcaa acaaccagca
    15001 gcaaggtaaa ggacaaagaa acaaaagatc gtacgtccaa acaattgcca gatgttaaaa
    15061 cagacgattg gaagctagtt ttggttggtc cagatcacaa attagaaaaa gaaattgatg
    15121 agtctactca attggcatca ttaagtaacg gatacttgat cgacaaacgc attgctccag
    15181 aatatgaagc atttgccaag gctgctgaag cagctggatt tccattagtg atggtctcag
    15241 cttaccggtc tgtatcatcc caacaacaag ttttcgaaca aaatgtccaa gatgtgatga
    15301 gtcgtcaagg tgtatcagaa gaggaggcga caaagattac taaagaaacg attacggagc
    15361 caggatacag cgaacaccac acaggtctgg cagtcgatgt cgtcgatcaa aactggtaca
    15421 acagttatcc ttctactgta ttggatgcaa gttacggaga tcagcctgga gctaaatgga
    15481 tcgcagataa tgctgcgcag tatggattta tcgttcgtta tccaaaagga cacgaagata
    15541 taactaagat cacatatgaa ccttggcact tacgttatgt cggtaaagaa aacgctgagt
    15601 atatcaccaa acaccaattg acgctagaag aatatctgaa tgaattaaat gaaaagtagg
    15661 aattgatcat ggcgaaaaaa aagtggaaaa agcaaaagcg caagaatatc cgttggccag
    15721 cagtggttgc cggtgtagca gtgatactct tagcctttgt tttttccttg aagaatctgt
    15781 cttctccttt tactgataat cagcaagaaa atgaagcgca atcccatcag caatttattg
    15841 aacggcttgt tccgcatgcc caagaactac aagatggtta tggagtgctt cctagtatca
    15901 ttttaggaca agctatatta gaatcaaatt ggggaaaaag taccttggct agcaaataca
    15961 ataatctttt cgggatcaag gcttatgggg atcagaagaa agtaagcctg gaaacaaagg
    16021 aatttgttaa cgaagaatgg ataactatcc aaggagactt caaagtgtat gattcatggg
    16081 aacagtccat ggatgaccat acacaactgt tcgtccaagg agtagattgg aatcctgcgc
    16141 tgtatgaaaa agtgattacg gccaccaact atcaggaagc cgcacaagca ttgcaagatg
    16201 caggttatgc gacagacccc ggttatgcgc aaaaaatcat ccaggtcatc gagacgtatc
    16261 aattgaatca gtatgaccgg agatagcaaa ggagaagtgg ctgatggcag aacaatttac
    16321 gccagaaatc atgacggaat tgagaaaaga tatcgtaaga gtaccggaaa tcattttaga
    16381 agcaagcggg atcaagatat ttggaaaatt gatccgttcg atcatcttta ctacggatat
    16441 tgcgatcata cgtaatacaa atgcgaatgc agtaattgct gtgtatcctt ttacacctca
    16501 tccagcgatt actaaaagca ttattgaggc agctgacatt ccagttttct ccggtgtagg
    16561 tggtggtttg acacaaggtg ctcgttcttc ctacatgagc atgttcgcag aagcgcaagg
    16621 ttcgttaggg gtcgttttga acggtcctac gcctttagag acagtaaaag aagtttgtcg
    16681 agtagttgat attccagtta tcagtacggt aacgtcgaaa tatacagaaa tagatgaaaa
    16741 gttagcagct ggtatttcga ttatcaatat cagtgcaggt aaagaaactg cagaagcagt
    16801 acgccatttt cgtaaaaaat atcctgaact tcctatcatt gcgacaggtg gtccaacgga
    16861 agaaagtatt gctgagacca ttcaagcagg agcaaatgcc atcacatata cgccaccaag
    16921 tagcggagag ctttttagtc gtaaaatgga aaaatatcgg gaaactgaga aaaagaatca
    16981 tgaataacag gtgagaatca aaagacgagg aagagcagat agtggctctt cctcgtcttt
    17041 tgtactccag tactatttgt tcagaattca aaaaaaagag aaattttttt gtttttttac
    17101 ctgtaatgta cataagaaga gttaaaacct tttgttatta ttagcattct aacaaaaaaa
    17161 tgtcttgatt tattgaagcg ctttctatag aatgaaaaac gaataaaaac taaaaaaggc
    17221 acccgacaat ttagtagcag ctaaattgtc ggggcttgaa aagtcagcgg gaactgacca
    17281 atcaagttgc catagtcaat gcttgtgcat cgacgtgtat attgtaccta atttcataca
    17341 gaattactag ttatttttct gttttttagg gaagagcgca cacgaagaag catgcttatt
    17401 tagctatgtc aaggatattg ggcagttgtc tgatatcctt ttttctttgc gtaattatcc
    17461 tcccatcatt gaagcaagaa gtgtttttag cgatgaaaga agaatcagca ctatctaatt
    17521 tttcttgaaa gtattgagtt gttcatccta ggcagaacga taaggcaagt cttggttttt
    17581 attccccttg aaaaagatcg tttaataaat atgttctgta taaaaataca gtatattgaa
    17641 aaataacaat ggaagtagag gtgcagagaa tgaagaaaag aatgagaatc atcttagctt
    17701 taagtgttat gttattcttc ttgacggctt gtgggcaaga agatgacaaa aaaatcacgc
    17761 tgaacatggc ttggtggggt tcgcaagtcc gacacgatgc aacagtaaaa gtaatcgagc
    17821 tttatgaaga aaaaaatccc catgtgacga tcgattatga attttatgat tatgaaggat
    17881 attacacaaa attaggtaca ctagcagcat cagatgatat ctgggacatt ttccaactga
    17941 acaatcaatt tcctcaatac atcaatcaga ttgaaccatt agatgaatat gtggagcaag
    18001 ggataattga tatttctaat gcagatgaat cctatttagc aacgacgact tacgacgggc
    18061 aattagttgg actgtctaac ggggtgaatt cgtttgcgat tgcttacaat aaaaatatat
    18121 ttgaacaatt aaatatccct gaaccagctt caaattggac atgggatgaa tttgaacaaa
    18181 tcagctatca aatcactgaa gaattaggaa tctatgctat ttcaagattc gaagatttta
    18241 tagctggctg tattattcaa ataccacaag ttgagaaagg attgaatttt tataatcggg
    18301 aagatctatc taacagcttg ggatttgaaa atccagacta tctaacagat tttttccagc
    18361 tgcgtaaaaa tctggtagac aaaggggccc atccagaacc aggtggtgga gctgcaagta
    18421 cgacggatct gtcttttcag gcggttaggg atagagaagc ggcaatggtg tttctatcaa
    18481 gtaaccagtt gacagaaata ttgtcagggg ctcctgaaga tatggagatt cagttgatta
    18541 atccacctcg cagaaaagca gatggagaat ctggtatccc tttacgttct tcgcaaatgc
    18601 tgagtatggc aaaaagctca gcccataaag aagaagctgc taagtttatt gatttctttc
    18661 aaaacagtga agaagccaat gaaattttaa aaggagaacg tggtgtacca atcatgtcga
    18721 atattcgaga acagctcgct cgtgcagatg atgcaacttt gcaagcgaca tttgattatt
    18781 tagaaatgat ttccgatatg gacaacggcg aagtgaatgt ctttgatagt gctttgaatc
    18841 cggaaattca agaccaatac aatcttttag ttgaaaaagt catttatgaa gaagtaacag
    18901 cagaagaagc agcagagagt ctttatgagt ttgcgtcaaa cattctagga tagcagcagg
    18961 aggaaggcat gaaaaaagaa aaactaaaac ggttcttgga tcaagacaat gtggtcggtt
    19021 acgtatttgc ttctccattc atcctaggat ttctattgat aacagtgata ccgatgatct
    19081 tgtcacttta ttattcgttc accgattatc gtttgggaaa tccagtctca tggatcggct
    19141 tggataatta tataaagatg ctgagtgatg cccgtttttt gaactccatc cgagtcactt
    19201 ttctctatgt atttgcatct gtacctgtga aactgatctt tggtctattg attgcttatc
    19261 ttttaacgag gaatatcaaa ggaacgactt tctttcgttc tttgtattat gtgcctagtt
    19321 tgatcggtgg cagtatttct atcgctctag tttggcggga gttgttttct aaaaacgggt
    19381 tagtgaatat tttcctggaa cgattaggcg cacctgcgct ttcctggttt agcgatcaaa
    19441 aactggtcat gatccctctt gttttgatgt ctgcttggca attcggttcg gcaatgatca
    19501 tctttgctgc aggtatcaaa gagatcccag gctcgtatta tgaagcggca gagatcgatg
    19561 gagcgaacaa atggcagacg ttttacaaga tcacgttacc tcttctttcg ccgatcattt
    19621 tgtataactt ggttatgcag acaatcgcgg cgtttatgac ttttacgcag gcatttatca
    19681 ttacccaagg tggtccgaat gatgccacga acttttatgc tctttatgtg tataaccaag
    19741 ctttttcttt taattctatg gggtatgcta gtgctatttc gtggatcatg ctgttgatta
    19801 tgggagctgt cacctttctg attttcaaat catcaaaaaa atgggtcgtt gtgtgaatga
    19861 gaggaggaag aaatgaataa tacagtaacg aaatggtttc aatacggttt tattttgcta
    19921 ttaggtctag tcatgattta tccggtctta tggatgatcg caggttcttt taaaacggat
    19981 caagagatta tgagtggttc gctgaatttg attccagaga cttttcaatg ggaaaattac
    20041 gcaaaaggat gggcggggtt tgctggaatt tcatttttta ctttctttag gaattcgttt
    20101 gtcatctctg cagtttcgac gatagggaca gttctgagct cgacttgtat tgcttacgca
    20161 ttatcgagaa tcgatttcaa aggaaaaaga ttctggttcg tcgtcatgtt agtaacgatg
    20221 atgattcctg cacaagtgat tttgattccg cagtttatta tttacaatcg gctgaatttg
    20281 gttgggacgt atgtgccgct gattttacca catttttttg gacaagcatt tttcatttac
    20341 cagatcatgc aattcatggt cagcatcccc aaagagttag atgaatcagc gattattgac
    20401 ggatgcagca agtatagtgt ctttaccaaa attatttttc ctttgctgaa accttcgatc
    20461 atcacgacga tcatcatcca gttttattgg aaatgggacg acttcatggg accattgatt
    20521 tatttaaaca agccgagatc ttacacggta tcgattgcca tcaaattatt tgcagacgct
    20581 ggatctagta cgacttacgc gagtatgttt gcgatgtcta cgttgtcgct gctaccggtt
    20641 tttctgattt tcttattctt caataaatat cttgtccagg ggatcagtac aagcggtctg
    20701 aagggctgaa tatgaaaaag ccaatagaag agatgtttct ttacaagctc aactactatg
    20761 tctgtcggat ttttttaacc agtcttatca gtaatgctct tttcgcttta gttctaggat
    20821 gtttgttcac tttaggatta gtgctgtctg ctcgtgttgt ctatctgatt tattttttga
    20881 tgatgtatcc ttcttattat ctatctgtcc attacttggc agaaaaaaag gtatgttgga
    20941 ggaaaggaaa aatcaaacgg atgtgtttca tcattacgtt gtttcagctg tttgtcatta
    21001 tttttgcagt tgattggtat ttattagtgg gaaagattgg agcttggtat ctgattcctt
    21061 ttctattgtg tctgttgctt tttgtatccc atagtttttt tagtacgcta attgatatct
    21121 gcaaagaaga taaagcagat agtcttgttt atttgatcaa aaggaatatc tggctgttgt
    21181 caaaaaacgt caaggggttt ctgtggtatt tatgcctttt gtatggactg ttctggtgta
    21241 tacagcatga ttttttactc actgcattac tgtatccagg gctgccattt gtcacagtat
    21301 tttgcttaaa agaaaaggag aatgacttta aatgaagaaa aaatatgtac aagtcggact
    21361 tggtgggaga gcgcgttttt tttatgaggc aattgcctct acgtatcatc aaacttgtga
    21421 actagtcggt ttttgtgatg tatctcaaac aaggatggat tatgcaaatc ggatacttgt
    21481 gaacaagtat ggacagaaaa aagtaaagac atgtatgcca tcacaatttg agcaactact
    21541 ggatgacgta cggccggctg aagtcattat tacgtcagta gatcgaacgc atcatgatta
    21601 tatcattcgt gcaatgaaaa aaggatatga tgttatttgc gaaaaacctc tgactatcga
    21661 tgaggaaaaa gctcaagaaa taataacggt ccaaaaacag acgggaagaa gcctgcgagt
    21721 cacttttaat tatcgttatg caccgtatca cacgaagata aaggaactga tagaaagtga
    21781 tgtgattggt gatgtgtttt ctatccactt cgaatggctg ttaaatacgc aacacggggc
    21841 agattatttc agaagatggc atcgaaataa gcacaatagc ggcgggcttc ttgttcataa
    21901 atctacccat cattttgatc tagtgaattt ttggttgaac agccgtcccc aaaaggtatt
    21961 tgcattcggt ggattaaact tttatgggat gcataatgcg gagaaacgcg gagtagaaat
    22021 attttacagt cgatgctatg gaagcgaact agctaaagct gatccatttg ctatagacct
    22081 gtcagccaat gaggaattgc gagaaatgta tttagaagca gaaaaagaca gtggatatat
    22141 tcgtgaccgc agtgtatttt ccgatgatat ctctattgaa gatacactag gcgtaacggt
    22201 caaatatgaa actggtgcga ttttgacgta ttcgctaaac gcgtatatgc cgtgggaagg
    22261 attcaatgtt tctttcaatg gcagcaaagg acggatcgaa atgaaagtga tcgaaaagtc
    22321 ttacatcaat gcaggtggag ataaaaagga tgaaggagca gccgttcttc agtccatcca
    22381 tgtctatccg atgttcggtg agccatatga ggtaatcgtc gaacaagaag cgggcggaca
    22441 tggcggagga gatccgcgtt tattagatga tctatttggt gaagaaaaag aagaagatcc
    22501 gtggaatcgg gcagcaactc acgtagatgg tattttgtcg attttgacag gaatcgcagc
    22561 aaatcattct attgcttcag gaaaagcagt agtgattgac gagcttgtca gcttaaaaga
    22621 ataagaatag atttacggaa attacttccc gtagtttata aaatcttgcc ttattgccga
    22681 taggctgtct tttgaacact atttattcgg aaaaaggggc tatgacatgc tttttgtcat
    22741 gccttctttt tatgtgggct gcttttttag ataggagaaa ataaaaataa ctatttaaac
    22801 ccgaacaaaa aggaataatg cattaaaaat cattagattt tacaaaaaaa taagtaaacc
    22861 acgttgtcag tttcagaaag tagtgttaga ctgttttcaa tatttgaaac aacatttttt
    22921 attcaaatat ggcaaactgc cttcacgtgc aaaacagttg caagaaaatg aatttacact
    22981 attattagtt ttacatacct acttatatat cgtcataata tggatgacag tttctagcca
    23041 gtaccgtaaa tgctggacta taagtaaaag attggctatt tcacccttct tttcttatga
    23101 taaagtggag ggtgtttttc tttaacagaa acatagtagg tttttgcaca aaagcggtta
    23161 tttcggtatt aataaatgat aaaggagcaa ataaagtgaa agaattagtt gaacgtattc
    23221 aaaaagacgg acgtatatta ggcgagggcg tattaaaagt cgacagcttc gtcactcacc
    23281 aagtagaccc tgtattgatg gaacaaatgg gaaaacggtt tgcagaagta tttaaagaac
    23341 aaggaatcac gaaagttgtg accattgaag cttctgggat cgcaccagct ttatttgctg
    23401 caagagaatt agatgttcca atgatcttcg ctagaaaagc aaaaagtttg acgatggatg
    23461 aagaattatt gacagcttct gtttattctt ttacgaaaca agtgacaagt acgatttcta
    23521 tttctcgtaa atttttatct tcagaagaca aagtattgat tatcgacgat ttcttggcaa
    23581 acggacaagc ggcaaaagga ttgatcgaat tatgccagca agctggagcg caagtagaag
    23641 gaatcgggat cgtcatcgaa aagtctttcc aagatggacg tcagttactt gaagaaatgg
    23701 gattgagagt cgtttctctt gcgcgtattg cttccttgac gaatggacaa gttgagtttc
    23761 ttgaggagga cgcataatcg tggaaaaaga aacacaaaat ggaaaagctg cggttttagg
    23821 gctgcagcat ctgctagcga tgtatgcagg agcagtagcg gtgcctcttt tgatcggtac
    23881 aggactaggc tttaatcaag aacagatgac ttatttgatt tcaattgata tctttatgtg
    23941 tggattagcg acattattgc aattgacagt taaccgattt ttcggaattg gcttgcctgt
    24001 cgttttagga tgtgcgatcc aagcagtagc tccactgatc ttgatcggaa ccaatgaagg
    24061 agtaggagct atctacggat ctattatcgc ttctgggatc tttgttgtgt tagtttctgg
    24121 tgtcttttct aaaattaaaa aactattccc tcctatagta acaggaacgg ttatcaccgt
    24181 tattggtttg actttgattc ctgtagcaat cgagaaaatg ggtggaggta atgcaacagc
    24241 agctgatttt ggtgacaaaa caaatctgct acttgcattt gtgacgattc tcctaattgt
    24301 aggcgtgcaa atgctggcaa aagggttcat tcgttcaatc gcggtattga ttggtttagt
    24361 cggaggaagc atcttagctg ctttcatggg aatgattgat ctgagcgcga ttggagatgc
    24421 gccgttgttc catgttccac aaccctttta ttttggtaaa ccaactttcg acgtatggtc
    24481 gattttacta atgatcatca tttccatggt cagcatggta gaatcaacag gtgtatattt
    24541 tgcacttggt gacattactg ggaaaaatgt tggagaagaa gaattgaaaa agggatatcg
    24601 tgcagaagga cttgccgtta tcttaggcgg tattttcaat acattccctt atactggctt
    24661 ttctcaaaat gtcggattgg ttcaactttc gggaatcaaa acaagaaaac ccatctattt
    24721 ctctgcattc ttcttgattg ttttaggatt attccctaaa atcggtgcgt tagcacaaat
    24781 catccctgag ccggtacttg gtggaggaat gttagtcatg ttcgggatgg tggcagtcca
    24841 aggaatccgt atgctgttgg aagttgattt cagcaatgat aaaaatctat tgattgttgc
    24901 tgtttctgtt ggatttgggc tgggtttcaa tgttacgccg acattattca gtcaaatgcc
    24961 gcaaacattg caaatgttca ctggaaatgg catcgtaatg agtagcatta cggctatcat
    25021 attgaatttg atctttaatg gattgaaaaa agatgaagaa atattggaag aagccttcaa
    25081 gaagtaatag agcaaaagaa aggttgtgaa atcagcgttt tgacctgatt gttagagaaa
    25141 caaacggaaa aatagttcct cgtattttgc cgtttgtttg agctaatacc gagggtcagc
    25201 tgattgaaca ccgttgaagg aagaggtcgt gagcctgccg ttcatctccg agtcacaagg
    25261 aacaatttca aaaaaaagct tctcatgttt gttgaatatt gttccttgtg accgaggagt
    25321 tggcaggaga acaccgttta tccataaaaa ggaatgtgac ctaacttttg tcacattcct
    25381 tttttttatc tttaataaac acgaacaata aaatgttttt ctttgttaac attcgaaatt
    25441 tctttgacat caaaaaaagt gattgttaaa atatgaatgt agaaaaactg ggaggaaaaa
    25501 caatgacagc aaaaatctct gtgattatgg ggagtacttc agattgggaa acaatgaaag
    25561 aagcatgtca aatattggat gaattcggtg tgtcttatga aaaaaaggtc gtttctgctc
    25621 atcgaacccc agatttgatg tttgaatatg cacaaaacgc tcgaaaaaaa ggaatcaaaa
    25681 tcattattgc aggagcaggg ggagccgcgc atctgccggg tatggtcgca tcaaaaacaa
    25741 ctttgccggt tatcggtgta ccggtccaat cacgaacatt aaatggtttg gattcgcttc
    25801 tttcgattgt ccaaatgcct ggaggagtac ctgtagctac tacagcaatc ggaaaagcgg
    25861 gagcaattaa tgctggacta cttgcgatac agatgctttc catgtatgat ttagaattgg
    25921 aggctaaatt ggctgaaaga cgttcaatgt tggctaaaac tgttatagaa agtagtgatc
    25981 aacttggtta aacctttgtt gcctggttca acgatcggga tcgtcggtgg cggtcaatta
    26041 ggtcgtatga tggcgattag tgcaaaagaa atgggcttta aagtaggtgt gctggatcct
    26101 gtgagcgatt gtccagccgc acaagttgca gattggcaca ttgaaagtgt ctatgatgac
    26161 acctttgcgc tgaaagagct tgccagaaga acagatgtca ttacctatga attcgaaaac
    26221 gtcagtgtag aggcgttaaa tgcgatttta cccatgtcat ttattcctca agggacagac
    26281 ttgcttgcga ttacgcaaga ccgcctgtta gaaaaatctt ttttggaaac gaataacatc
    26341 gtgattgctc cttatgcaac gatcgtcagt ccgacggata tccaagatgc gattgacggg
    26401 atcggctatc cttgtgtttt gaaaaccact cgaggcggct atgatggcaa ggggcagtat
    26461 gttttgaaaa gtcgggcgga tctagctcct gccatggacc ttttaagaga aggaacctgt
    26521 gttttagaag catggatccc gtttgaaaaa gagatttcga tcatggtggc aggaaatggt
    26581 caaggagatt tcacgacttt tccggtcgtg gaaaacatcc accacaacaa tattcttcat
    26641 gaaacgattg ctccagccgc gattgatcag gatgtgatcg aggaggctga gcgtattgcc
    26701 cgtgtgattg cagaagcagt gagcctttca ggtgttttag gggtagaaat gtttttaaca
    26761 aaaacaggcg ggctatatgt gaatgaatta gctcctcgtc ctcacaattc tggacattat
    26821 tctattgaag cttgttctat gagtcagttc gatgcccata ttcgaggtat ttgtggttgg
    26881 ccattaggag aaaaagtacg tttgataagc aatgcagtaa tggtcaatgt tttgggagaa
    26941 caactgctgg aaagctatcg cttgattgag aataagccag actggcaatt ccatttctat
    27001 ggaaaaaaac aagcaaaaaa aggtcgcaag atgggacata tcactatctt gacagaagac
    27061 atccagcaaa cgctggaaga aatcaaacaa acgaatattt gggattagag gagaaaaaac
    27121 atgttagaac gttatacacg ccctgaaatg gggaatatct ggacggaaga gaacaaatac
    27181 cgtgcgtggc tcgaagtcga gattttagca gatgaagctt gggcagaact tggtgaaatc
    27241 ccgcaagaag atgtgaaaaa aattcgtgag catgcatcat ttgatatcga tcggatcttg
    27301 gaaatcgaaa aattaacacg ccatgatgtc gttgcgttta cacgagcggt ttctgaaaca
    27361 ttgggagaag aaagaaaatg ggtccattat ggtctaacaa gtacggatgt cgtagatact
    27421 gcttatggct atctcatcaa gcaagcaaat gatattttac gggaagactt gaaacgtttt
    27481 acggaaatca ttggcgaaaa agcaaaagaa cacaaatata cagtgatgat gggtcggaca
    27541 cacggtgtcc atgctgaacc aactactttt ggattgaaac ttgccacatg gtattcagaa
    27601 atgaaacgga acatcgaacg atttgaacat gcggcaaaag gagtagaagc aggaaaaatc
    27661 tcaggagcag tgggaacgtt cgcaaatatc ccgccattta ttgaagagta tgtatgtaaa
    27721 caattgggga tccgtccaca agaaatttct actcaagttc tccctcggga tctacatgct
    27781 gaatatttct cagcgatggc gcttattgct acaagtattg aacgttttgc aacagagata
    27841 cgcggattgc aaaaatccga aacacgtgaa gtagaagaat tttttgcgaa aggtcaaaaa
    27901 ggttcttctg ctatgccgca caaaaggaat ccgatcggtt cagaaaatat ggctggtcta
    27961 gccagagtgg tgcgcggaca catggtcact gcctatgaaa atgtcacatt atggcatgaa
    28021 agagatattt ctcattcttc agcagaacga atcatcttgc ctgataccac gattttattg
    28081 aattacatgt taaatcgttt tggcaatatc gttaaaaatc taacggtctt tcctgaaaac
    28141 atgaagcgga atatgtctgc aacatttggt ttgatttata gccagcgcgt tatgctgaaa
    28201 ttgatcgata agggaatgac aagagaagaa gcttatgatc ttgttcagcc aaaaactgcg
    28261 tacgcttggg acaaccaagt gcagttccgc ccgctgttag aagaagatcc aaccatcaca
    28321 tcggtattat ctaaagaaga aatagacgat gcctttgatt atcatcatca tttgaaaaac
    28381 gttgacgtga tattcaaacg agtaggtttg gaataaagaa gagtgagttg caaaattcaa
    28441 ttaaaataga atagcaaaaa taaccaaaaa agaagcagat ccgttagcgg ttctgcttct
    28501 tttagtttat tatattttct tatcaataat aggaacctga ttttaaaagc ggctacctct
    28561 ttaccgtgcc tctttacata caaaaaatag aggaattaag cgtaaatggc ttggctatta
    28621 taactaaaat gctggttatg gagatgttgc agcaagtttt cgagaaaagc gtattccatc
    28681 tcttgtccat tgaataagat ctggatacga taatgatttt tgaaacgctt ctgttcatga
    28741 atctgactga ttgaaagttc gcctttgtgt tctgtctgat aaagaaaagt ccttttacgg
    28801 cattcagcac agcgcttggt tgctcggcgg atttttcgga atgtataaaa actagtatct
    28861 ttattgcata aataaacgtc tttgatcgac agcaaatcat tatatagaca ggaacgttct
    28921 tcagctgtta attctgataa aaaaagctga ccttgtttta ttgcatcttc catcggcaag
    28981 tgcctcctcg aacccattat ccaaattttt agttaattct aatataccat cattaagtat
    29041 aaatgtaaac gcttgttgat ggtataagat tttcgtttct gataaaacac gaacattaaa
    29101 agaatctaat gccttaaatg tacatatttt tgttgattta taaaaagatg attgctaaaa
    29161 tttaaagtga aaaaacgaac aaaaaacgat gtatttgctt ttaatgtaaa taaaaaggag
    29221 agacgtacat ggagaagaaa gaacttttgt atgaaggaaa agccaaaaaa atatatctta
    29281 cttctgatga gaacttgatt tggatagaat atttagatca agcaactgcg ttgaatggcg
    29341 cgaggaaaga ccagataagt ggaaaaggag aattgaataa tcaaatcaca agtgcaattt
    29401 tccgttatct gactcaaaga ggaataaaaa atcattttat tgaacaattg tctaaaaccg
    29461 aacaattagc aaaaaaagta caaattatcc ctctggaagt ggttatccga aatattgcag
    29521 caggaagttt ctcaaaacgt ctaggtgttc ccgaaggtaa agaattcatc aaaccaatca
    29581 ttgaattcta ctataaggat gaccagttgg atgatccatt tatcaatgaa gagcatatct
    29641 atttcttaca acttgcaaag ccggaagaaa tcagtgagct gaaagcccaa gcgttggcta
    29701 ttaatgaaat tttgaccgaa ttatttgcta aggtcggttt ggttttagta gatttcaagc
    29761 tagaatttgg ccggtcgaat ggacaaattt tgcttgcgga tgaagtaaca ccggatactt
    29821 gccgattatg ggatgaacgt acgaatgaac atatggacaa agacgtttac cgcagagatc
    29881 taggtgattt gatcccagtc tatcaagaag tatataaccg tctatcggaa ctaactgaag
    29941 aaaaggagcg agtatgatgt atttcgtaaa agtatatgta acctataaag attcagtgtt
    30001 agatcctcaa ggggaggcag taaaaaaagc agtccatcgt atgggatatg aaacaatcga
    30061 agatatccga ataggaaaat actttgagat acaacttgct gatgcagaag aaccaatcga
    30121 tacagtgatt gaaacgattt gtgacaagct gcttgcaaat gtaaatatgg aaacataccg
    30181 atatgaaatc aaaaaaatgg aggaagtata acatgaaatt tgcggtcatc gtttttccag
    30241 gttcaaattg tgacgcagat atgttatggg cagttcgcga gatcatgggc gctgatgccg
    30301 aatttgtacg gcatgatgag tcctctttag aaggatttga tggggtttta ctgccgggag
    30361 gattctccta tggtgactat ttgagatgcg gtgcgattgc tcggttttct acaatcatgg
    30421 aagaagtgat tcgttttgct gaagaaggga aaccagtatt cggtacatgc aatggattcc
    30481 agatattgac agaagcagga cttttgccag gtgtactgag acgaaatgag tctttgcatt
    30541 ttatttgcaa aactgtacca ttgaaagtca accccaagac ggcctttact tcagagtatg
    30601 aagccgacga aataatctat cttccagttg ctcatgggga aggaaattat ttctgtgacg
    30661 aagaaacact tcaagaacta aaaaaaaata atcagattgc ctttacttat aatgacaaca
    30721 tcaacggcag cgtggaaaac attgcaggga ttacgaacaa agcagggaat gtgttaggaa
    30781 tgatgcctca tccagaacgt gcagtagaag acttgctagg atcagaagat gggaaacggt
    30841 tctttgcttc cattttaaaa aacttcggaa aggtgaccgt atagatgaaa acattgaaag
    30901 aaccgacagc tgaagagatc aagaaaaaaa gaatctatgc cgaatgggga ttgactgatg
    30961 aagaatatcg aatgatcgaa gaagatatct taggaagaat gcctaattat acggaaactg
    31021 gactgttttc tgttatgtgg agcgaacatt gttcctataa aaattctaaa ccggttctac
    31081 gcaaatttcc tactagtgga cctcatgtgt tgcaaggccc tggagaaggc gcaggcatcg
    31141 tcgacatcgg tgatggacta gcagttgtct tcaaagcaga aagtcacaat catccttcag
    31201 ccgtggagcc ttatgaagga gctgcgacag gagttggcgg aatcatcaga gatattttca
    31261 gcatgggggc tcgtccaatt gcgttgctag attcattgag gttcggcgaa ttagataatc
    31321 caagaacgaa atatttacta gaagaagtag ttgcaggtat cggcggatac ggcaattgta
    31381 tcggcatacc gactgtaggc ggcgaaattg catttgatcc ttgttatgaa ggaaacccat
    31441 tagtcaatgc aatgtgcgta ggtttgattg aacacaaaca tatccagaaa gggcaagccg
    31501 ctggcgtcgg taattcgatc atgtatgtag gtgcaaaaac aggtcgcgac ggtatccacg
    31561 gagcaacttt tgcctcagaa gaatttaatc aagaagaaga acagcaacgt tctgctgtac
    31621 aagtaggcga tccttttatg gaaaagctgc tgcttgaagc gtgtttggaa ttaatcttgc
    31681 atcattcgga ttctctaata ggtatacagg atatgggagc agcaggactt gtttcatcta
    31741 gtgcggaaat ggcttcaaaa gctggctcag gacttatatt gacattagat gaagtcccac
    31801 aaagagaaac tgggatgaca ccttatgaaa tgatgttatc ggaatcacaa gaacggatgt
    31861 tgatttgtgt taaatcagga gaggaagaaa aaatccaaga actatttcag aagtatgatc
    31921 tagatgcagt cactatcggt aaagtaacag acgacgggca atatcggcta tatcatcaag
    31981 gagaagaagt agcaaatctg ccagtcgatg cattagctga agatgcacca gtttatcata
    32041 aagaaatgaa agaaccagct cgaatcgtag aatttcagca gttagctcct tatcagccag
    32101 ttatcgaaga acctggacaa gtattgcttg atctgctgca gcaaccgacg attgcttcaa
    32161 aacgttcaat ctacgaaact tatgattcac aagtacaaac caatacagtt gtccgtccag
    32221 gaagcgatgc tgctgtgatg agggttagag ggacgaataa agcgttagct atgaccacag
    32281 actgcaacgc gcgctatctg tatttggatc caaaaatcgg aggacaaata gcagtggcag
    32341 aagctgctag aaatattatt gctagcggtg gtaagccctt ggcgatcacc gactgcctga
    32401 actatggttc tcctgataaa ccagaagttt tttgggaatt atcgacttca gctgacggaa
    32461 ttgctgctgc gtgtgaaacg ttaggaactc ctgttatttc aggaaatgtc tctttatata
    32521 atgaaacgga tggtcaagca atctatccaa caccaatgat tggtatggtc ggattgattg
    32581 aggatcataa acatatcact actcaggaat tcaaaaaatc aggggatcta atctatatat
    32641 taggtaagac gtttgcagat tttgatggca gtgaattaca aaagatgcag cttggaagaa
    32701 tcgaaggtgt gatccgaaac tttgatctat ccattgaaaa gagaaaccaa gagttagtat
    32761 tgacagccat ccaaaacgga ttgattgaaa gtgctcatga ctgttcagaa ggtggcttgg
    32821 caattgcact ggcagaatca gctttcaaac atcagctagg gatatctgta cagtttgaat
    32881 tgtcctctgc tcaattattt gcagaaactc aatcaagatt tgtgttgaca gtcgcaccgg
    32941 aaaataagac acgattcgaa gaaatgatgg gagatgctgc tgttttagca ggtaaggtga
    33001 cggatgaagc gataatcgaa atttcagcaa ctgacggtca gatcaaaata gaaactgcag
    33061 tagcaagaaa gtgctgggag gatgcaatcg tatgtcttat gaagtgaaga gtttaaatga
    33121 agaatgcggg atcttcggtg tttggggtca tccagacgcc gctagtgtgg catacttcgg
    33181 gctccatagt cttcagcatc gaggacaaga aggtgcaggt atcgtgtcca atgatcgagg
    33241 aaagcttaag gggcatcgag atttggggct gctttctgag gtattcaaag atcaaagaaa
    33301 attgcagcag ttaacaggag aagctgcaat cggacatgta cgttatgcaa cagcaggcaa
    33361 tggaagtgtg gacaatattc agccttttct attcaaattt catgatcagt cgatcggctt
    33421 agcgcataat ggtaacttga tcaatgctcg ttcccttaga aaagagttag aggaaaatgg
    33481 ggcgatcttc cattctaact ccgatacgga gatattgatg catttgatcc gacgaagtga
    33541 agaaacagat tttttaaata aattaaaaag tgctttgaat gaagtcaaag gtggctttgc
    33601 ctatttatta atgacagaaa cggcaatgat tgccgctttg gacccaaatg gttttcgtcc
    33661 attagcaatc ggacaaatga aaaacggagc atacgtgatt gcctcggaaa cttgtgcatt
    33721 agaagttatt ggggcacgtt ttataagaga tgtccagcct ggtgagatag tgatcatcaa
    33781 tgacgaagga atccagattg attgctttac gaaggacacg cagctttcta tttgttcgat
    33841 ggaatatatc tattttgcca gaccagattc aaacatcgca gggatcaatg tgcatactgc
    33901 acggaaaaat atgggacgga atttagcgaa agaatcgcca gtaaaagcag atatggtcgt
    33961 tggcgtacct aattcttctt tgtcagccgc aagcggttat gcggaagcta gtggaatccc
    34021 ttatgaaatc ggattagtaa aaaatcaata cattgcccga acatttatcc agccaacgcc
    34081 tgagctaaga gagcaaggtg ttcgaatgaa attatctgct gtacgaggag tagtggaagg
    34141 taaaaaggtg attatggtcg atgattcaat tgttcggggt acgacaagca gacggatcgt
    34201 ccatcttttg aaagaagcag gggcaaaaga agtccatgtg aggattgctt ctcctccttt
    34261 gaaatatcca tgtttttacg ggattgatat tcaaacgcgt aaagaactca ttgcggcaaa
    34321 tcacacgatt gatgaaatca aagaatgtat cggtgcagat tctttaggtt ttttaagtga
    34381 agagggtctg atcgaatcga tcggtctgga aaaagatgct ccgtattcag gattgtgtat
    34441 ggcttatttc aacggagatt atccgacgcc gttatatgac tatgaagaaa aatatcagga
    34501 atcactaaaa gaaaaagtat cgttctttta aaagcagacc aagaagggag tatatgaatt
    34561 caatggcaaa tgcatacgca aaagctggcg tagatgtcga agctggatat gaagtagtag
    34621 aacggatcaa gaagcatgtc aaaaaaacgg aacgtttagg tatgatgggc gctataggag
    34681 gattcggcgg ttgttttgat ttatcggtct ttcaattaaa agagccagtc cttgtctcgg
    34741 ggaccgatgg cgtggggacg aaattagcag tggcaatcga agcagacaaa cacgatacaa
    34801 tcgggatcga ctgcgtagcg atgtgtgtca atgatatctt agcacaaggc gcagagccgt
    34861 tatatttctt agactactta gcaacgggga aaaatgatcc gttacgtttg gaaaatgtag
    34921 taaaaggtgt agcagatgga tgtgttcaag gaaatatggc gctgattggc ggagaaacag
    34981 ctgaaatgcc tggtatgtac tcaggtaatg attatgatct agccggattt gctgtaggga
    35041 tagctgaaaa atctcaatta ttgacaggag aaacgatcaa cccaggagat gtgttgcttg
    35101 gaatagcatc tagcgggatt cattcaaatg ggtactctct tgttcgcaaa attttctttg
    35161 agcagcagca gttttcttta tcatcaaaac tgccagaatt gaaaaaaaca cttggcgaag
    35221 aattgcttga gccaacgaaa atctatgttt cttccttgct tccgctgatc aaagaaaaga
    35281 aaataaaagg agctgcacat atcactggtg gagggtttgt agaaaatatc ccgcgaatgt
    35341 taccagaatc tatggctgca caaatcaaac ttggctcatg gccgattctt ccaatattcg
    35401 gctgtttaca aaaatatggt gaaattcctg agatggagat gtatgaaatc ttcaatatgg
    35461 gcatcggtat ggtcctggca gtcgaagaat cgaaagtaaa agaaatagta cacgaaattg
    35521 agcaagctgg cgaaaaagtt tatgaaatcg ggaaagtgat cgccaaagaa aaacatcgtg
    35581 tggtgtttat aggagaagaa cgatgagaat cgctgttttt gcttctggaa acggaagcaa
    35641 ctttcaagcg ctagccgatt atctatcgaa aaaaggattg gaatcttcga ttgactggtt
    35701 gttttgtgat cagcctgaag catatgtttt gaaacgtgca actgcgttga gtgtaccggc
    35761 agattgtttt tcacctaaag aatttgattc aaaaaaagag tatgaagaag caattttgca
    35821 taaattgaaa gaaaaaaaga tcgatttgat cgtattagct ggatatatgc gaatcattgg
    35881 accggtattg ctgaaaaatt atgataaaag aatcatcaat atccatccgt ctcttttacc
    35941 tgccttccct ggtttgcatg gcatacgtga tgcctttgaa gctggagtaa aagaaacggg
    36001 tgtcacaatt cattatatcg accaaggtgt agatactgga ccaatcatcc ggcaggaaaa
    36061 agtgagaatt gaacaggagg acacgttcga ttctttagaa gaaaaaatcc atagagtaga
    36121 gcatcgaatc tatccagaag tgattagtga aattattgaa aatggaggct atctgaaatg
    36181 acaagagcat tgatcagtgt atcagataaa actgggattg tagcattcgc ccaaggtttg
    36241 attgaacaag gagtagaaat catttcaaca ggaggaacaa agcatgcgtt ggataaagct
    36301 gggatcaaaa cgctttcgat cgaagaagtg acagggtttc ctgaaatgat ggatggccgt
    36361 gtcaaaacac ttcatcctaa aatccatggt ggtcttttag gaagacgcga tctccctagc
    36421 catatggagg caatggaaac ggaaaatatc caaccaatcg actttgtttg tgtcaattta
    36481 tatcctttca aagaaacgat tatgaaacca gatgtcgaaa tagcagaagc tattgaaaac
    36541 attgatatcg gtggtcctag tatgctccgt agtgcagcaa aaaaccatga atttgtcacc
    36601 tctgttgttg atccatctga ctatgaagaa gtactttcag aattacgtca gtatgggcat
    36661 acttcacttt ctttcagaca aaaactagcg gcaaaagtct ttcgtcatac tgcggcatat
    36721 gatgcactga tcgctcaata cttaacggat tgggtggaag aaaaagaacc ggaaaaattg
    36781 acacttacgt atgaacgaaa acaaacgctt cgttacggtg aaaatagcca tcaagccgct
    36841 gccttttatc agtccgctct tctggaaaaa tattcgatcg cagcagcaaa acaactccat
    36901 gggaaagaac tttcttataa taatatccga gatgcagatg ctgcgctacg gatcatgaag
    36961 gaatatgacg agccaacggt agtcgccttg aaacacatga atccttgtgg tattgggaca
    37021 gcatctacga ttttagaagc gtgggaagca gcgtatgaag cagatcctgt ttcaatcttt
    37081 ggtgggatca tcgttttgaa tcgagaagta gatctgccaa cagcagaaca gatgcataag
    37141 ctgtttctag aaatcatcat tgccccttct tatacacaag aagctttgga attactgcaa
    37201 aaaaagaaaa acatccgatt actgacagta gactttgcgc aggaagaaaa tcaaaatcga
    37261 gaagaaacgg tctcagtctt aggtggactt cttgtacaag atcaagatct ggcaatagaa
    37321 aatgaagaag agtggaaagt cgtgacaaaa cgtaagccga ctccagcaga agcaaaagca
    37381 ttagtgtttg cttggagagc tgtcaaacat gtgaaatcta atgcgatcgt actggcaaac
    37441 gaacgtcaga cagtaggaat cggagccggg cagatgaatc gagtcggttc agtaaaaatt
    37501 gcgattgaac aagcgcaaga gaaaatggaa ggtgcagttt tagctagcga tgcttatttt
    37561 ccaatggatg attcggttga atatgcagcc aaacatggta taaaagcaat cattcagcca
    37621 ggaggaagca tcaaagacca agattctatt gatatggcga ataaatacga tctagcaatg
    37681 gtctttactg atgttcggca ttttagacat tagagaggag tcggataaat gaacattttg
    37741 gtgatcggtg caggtggtcg tgaacatgca ataagtaaaa aacttttagc cagtccgaag
    37801 gtggatacgg tgtattgtgc gccaggaaat ccggggatga caaaagatgg tatcaattgt
    37861 gtcgctatca gtgagcgaga tcattcagcg ttaatccatt ttgttaagaa agaggctatt
    37921 gattggagta tcgttggtcc tgaagttcct ttgttaaatg ggatcgtcga tgattttatg
    37981 gcggaaggat tgaaaatctt cggtccgaca aaagcagcag ctctgatcga aggttcgaaa
    38041 agttttgcta aacaattaat ggatacttat caaatcccga cagctaaatc cagaagtttt
    38101 gaatgttacg aaaaagcagc agcgtatatc aaagaaaatg gtgcgccaat cgtagtgaaa
    38161 gcggacggct tagcagctgg gaaaggtgta gtcgtggcta ccacagtgaa ggaagcgctg
    38221 gatgcggcag aacaaatgtt gaaccagcat cgatttgggg atagtagcaa aaaaatcgtc
    38281 gtagaagagt ttttggcagg agaagaattc tcccttttgg cgtttgtccg taataccaag
    38341 gtgtatccga tggtcatttc gcaagatcat aagcgggcat ttgataacga taaagggcca
    38401 aatacaggcg gaatgggtgc ttattcacca gtaccgcaaa tttcaaaaaa gatgattgaa
    38461 aaagctgtgg aagaagtttt aaaaccagcg gctttgggaa tgaaagaact aggacgctct
    38521 ttcacgggtg ttttatatgc gggtttgatt gctacgaagg aaggaccaaa agtgatcgaa
    38581 ttcaatgcgc gtttcggtga tcctgaaacg caagtcgttc tttctcggtt gaagagtgac
    38641 tttgcgcaag taatcgatga tttattagag aatcgtacag tagagttaaa gtggcagcaa
    38701 gaaggataca atgtaggcgt tgtggttgca gctgccggtt accccgaaga atatgagaca
    38761 ggaatggttc taccagattt tctggaagaa gagctttctg tttactatgc tggagtttcc
    38821 tcaaataacg gcaaactagt tggagcagga ggacgtcttt atttagtaga agcatacggt
    38881 gagacgatca aagaagcaca gaaaaaaatt tacaccgcgt taatggataa aacgacagat
    38941 ggaacatttt atcgtacaga tattggagaa aaagctgcca atagcgaact gatcgtgaag
    39001 taaatcagct gcttccattt ataaaaaata caacaaacat aatcggaagc gccgatttta
    39061 gtgaagcctt ttcataaaga gtgtggtaca cttttgttgt gtatataaat aaggaggagt
    39121 tcagatgaaa aaaattcaat taggtacttc tgatcagaaa gcagctgcag tgatcttagg
    39181 ctgtatgcgt atcaacaatg cggaagatcc agtaaaagtg attgagacag cttatgaaaa
    39241 cggcattgat ttttttgacc atgcagatat ttatggaaac ggtgaatgtg aagaaatctt
    39301 tgcagatgct ctagcaaaaa catcaatcaa acgagaagat ctttttattc aaacaaaatg
    39361 tggaatcgtt ccaggtgtga tgtttgattt ttctaaaaaa catatcattg aatctgtaga
    39421 aaaaagtttg acccgtctga aaatggatta tgtggatgct ttacttcttc atcgtccaga
    39481 tacattggta gaaccagagg aagtagctga agcgtttgat gaattggaac ggtcaggaaa
    39541 agttcgttat tttggcgtca gcaatcaaaa accaatgcaa atcgaattgc tgaaaaaata
    39601 tgttcgtcaa ccattagtag ctaatcagct gcaatttggc ttgaaacata ctggaatgat
    39661 cgatcaaggg attcatgtca atatgacaga tgaagcaagt atcgatcatg acggtagtgt
    39721 acttgattat tcccgattgc atgatatgac gatccaagca tggtcaccat accagtatgg
    39781 attttttgaa ggtgtattta tcgggaacga aaaattccct gaattaaacc aaacattaga
    39841 agaactagca gctaaatatc aaacgacacc aactggcttg gcttctgctt ggattttacg
    39901 ccatccagcc aatatgcaag tgatcgccgg tacgatgaac gtagggcgaa tcaaggaaat
    39961 cgctcaagct tcagaaatta atatgtctcg ggaagattgg tacgaattgt accgtgctgc
    40021 tggaaacatt ttaccttaaa gattgtcata agcaggtcaa aagggctata aattaaaaag
    40081 acagaataac ttgaaagctg ttttcagctt cgagatattc tgtctttttt tattgcaaat
    40141 ggaaagagta tcattgtacg gatttcgttt attagttatt tttgttttta aggaaaagct
    40201 gtgtccgata ttcttttgga gaaatccctt gttttttctt aaataaataa ctgaaatagt
    40261 tagggtcatt ataaccaatt tcaaaagcaa tatctgaaat acgatagtct gattgctgca
    40321 ataatttttt tgctaattcg attctttgtt ctgtcagata atcgatgaat gtttggttaa
    40381 acgattgaga aaaaatcgta ctgaaatgag agggacttaa tgcaacttgt tgagcgaccc
    40441 aagttaagga catatctgga tcggtaaaat tttctttgat aaaatccaat gcatggttca
    40501 aaattggctg atatttgttc cttgaaggct gtgagggcag agcagttaag aaagaaatga
    40561 acatataaac tgtcgaacgg taaagcgagt cgtcggcgct gattgctaag cgttgactgg
    40621 tggatgtgca atgaaccatt tcttgcggga ttttcttttc tttcaggcag acatgctgga
    40681 gtagcttagt caagacaaat aaacgatata atcgtgttcg agttggtgtg ccttgtggtt
    40741 tcgtcaagtg ttcgatgtac ttagatactt cgtttttcga taatgaagac aaatcaagtg
    40801 agaggtcaaa gtaaaagaca gaatcaactg gaagtttcgc ttcttgaatc aaatcctcat
    40861 agctgataat ttgttcttta agggaactgg cggtttcaag tatcatctgc gtgatctcaa
    40921 aagatgcagg taattcgctg attctttctg cgacaggacc aatggcgaca gaaaaattat
    40981 ttttttgtcc cttttctaat tcatggacca acgtttgggc tacctgataa ctggtctcga
    41041 tcacattttc ttcaagagaa tcaactatta aaaatttgat gaatcgagag gaaacagcag
    41101 agaagatcac ttgttgattc tccctaaata aaaacttcaa ataatcactg agatgagcgt
    41161 aatcttcaaa gtctgtactg acttggtttg ctgctaataa tacggtcatt tttttccctg
    41221 ctaaagagcg attgaaagat tcagcaagtt tcaatgtttc actgatcgta agtgagcctt
    41281 tgaacaaacc gttcaagaaa tgattttttt tcaattcgaa aacaagatca gaagaagtgt
    41341 gcgtttcttt ttgctgcaaa tctaaagcag ttactgcttt ttctattgct tgtttcaatt
    41401 cgctactttt aatcggttta agcagataat catctgcctg tacctggatt gctcctttca
    41461 tataatcgaa atcgtcgaat ccactaataa atatgagacg agtccaagga agtagtttcc
    41521 ttgcttcttt tgaaaaagtc aacccgtcca tgaaaggcat ttggatatca gtcagaatga
    41581 tgtcgggctg taagtcgata attgaagaca gtgccatctc accatctcca gcttcgccga
    41641 cataagtgat tggataataa gaaccaagga cagttatttg ttcccgcaag ttattgcgaa
    41701 tgaggtattc gtcttcgatg ataaaaactt tatacatgtt tgtttcctcc aattgttttg
    41761 ggagatagag ggatcatcag tgtgacagtt gttccttctc ggtatttgct gtcaatcgtg
    41821 ataggttttt gatcatttcc gtaataaaga aggagacgct tgtttacgtt gtaaagtccg
    41881 tagccgatac tgaaatctga atcgatccct ttggctaact ctttacgtat ttctgccagt
    41941 ttttctgcag ggatgccaat cccgttgtct ataactttga attggatcat ctcatcaatt
    42001 ttgcatgtgg taatacgaat aaatcctttg tgacggacgt acttcgttcc atggtataca
    42061 gcattttcaa tcaatggctg caagatcatt tttaaaatag aaacaggaaa aagtgtttct
    42121 ggtatatcga tcttatagtc aagcatatgg ccgtatctta tttttaagat gactagataa
    42181 tcattgatat ggctaatttc tttttcaaga ggaatccagt cttgtccttt gcttaaagac
    42241 gtacgaaaaa agccggaaag tgcatgggtc atagtcagag cttcttcaaa gcagtcttgt
    42301 tcgatcaaag aaataatggc atccaaactg ttataaataa aatggggagt aatctgagct
    42361 tgcaatacac gaacttcact ttgtgctaaa tggtattgtt tcaaagcgtt ctcccgtaaa
    42421 gactggttta gatcttccgc cattttattc atgctagcgg taagtgtttg taattccagt
    42481 gtttccggca gggttaaacg aaagccaagg ttccctgaag aaagttgttc tgacatctcg
    42541 atcagctgat tgatcggttc ttggaccttt ctctctaaaa agcgacgatt ctttttcgca
    42601 tagaaaaaaa tggtactaag aactccaagt tccactattg ttaatagaat gagcgagcgg
    42661 acaagtgtcg tatttttttt gcttgctaag tcgatctcca cacgaacaaa atcttgtaag
    42721 atatctgaca gcagttgagt gacagaatct acctgattga tgatctcttc attggtatcc
    42781 ataaaatctt ttgccaagat attattgatc agctcgtttt gataatcttc cagtgtatcg
    42841 atcgtacgta gcgatacatc taacgtacta atttctttaa gtgtatttgt attatttttg
    42901 atctctcgaa tatcattcct aagttcttct aggatatttt cctcattgaa ctcatctacg
    42961 gttacttggc cagaaatcaa gtcccacata ctttccaaaa ctttttgatc aaccttcaaa
    43021 gcaattgcat ctgctttttg gatatttgcg atcgtctgtt gataaatcaa aagctgttgc
    43081 gaatataaca gtatgctcag tagcaaaggg ataacagcaa atagaagcat ggctttgttt
    43141 gcttgggcaa aaatctgttt tatgcttaaa ttttttgtca tgatacttct ccagtcaata
    43201 atttctggtt gggatgttag ctatattctg ctgggaaaag acagtctcgg aaataaaaat
    43261 atctttaggt aatgtttttc ctgtttgaat atttccaaaa taacgagtaa cggtattggc
    43321 tacataccag ccgacatcag gtttacactc gactacacaa ttgacgattc ctgagcgtag
    43381 cttctcgatc atatcttctt gtccatcaat agttacaatg atcaaatctt ctccaggttt
    43441 gattgatgtt tcttttatcg cagctaaagc accgtgagtc atttcatcac tatggctgta
    43501 taatacatcg atttcggata aatcatttgt ttctaaatat cgtttcatct ggtcttttcc
    43561 tttcatccga ataaaatcac cgacaattcg gtgaacaata gtcatcggag gtttatggtc
    43621 gatggttcca tcttttttta gggttggttt acgattgatt gattccaaaa atccttcgga
    43681 gcgtagcttg gtcggtgtgg agttctctga accagcaagt tctaggattc tgatttcctg
    43741 tttctttgaa tttgtgaagt gattgctgac aaataaaccc gcccgatttc cttctgcttt
    43801 gaaactgggg ccaatgtggg tgacgaaaag ctcgggatca ttcgtttgaa tatgtctgtc
    43861 gacaagtatg acagggatcc ctgctcgctt tgcttctttt aatacagagt cccacccgga
    43921 ttcttgcaaa ggagtaaaaa tgatcatatc cactttatag gcaatgaacg tccgtatatc
    43981 ttggatttgc cgttcctgat tcatgtagcc atttcggtag agaacttggt aatcttcttt
    44041 ttcaagcgca gtgataattg attcagtatg ctttttccgc cagctactct ccgttcctga
    44101 ttgcgaaaaa ccaacgacta gtgggtcagg tgcttccttt gtattaggtg tacaccccat
    44161 catttggtaa gcgattacaa caagggctaa aaaaaataaa acacgtttca ctttaaatca
    44221 ctccatctgg atttgttagt actatcttat cagataaaag ggaaaatcaa agtcaaaagg
    44281 aatcaatcga aaaaaatcca agaaacttaa aaaaatccaa gacaaaaaaa gtacacctaa
    44341 aaaatttaaa gtaaatccca taaaaaaatc aatgttaacg ctttctttat tagctatact
    44401 cggtgtatca attgaaatgg gggataaaaa atgaaaaaca aatttagaaa gattgttggg
    44461 actatcgcta ttttgaccgc aagcattcta ttaagtgcgt gtggcaattc aggatctgca
    44521 gatgatagta cggggtatgt aggaatcgct atgccgacca aatcagcaga aagatggatc
    44581 gctgatggga acaacatggt ctcggaatta gaaaaactgg gttataaaac agatcttcaa
    44641 tatggagaag ataaagtaga aaatcaagta gcacaaatag aaaatatgat tacaaaaggg
    44701 gtagatacac ttgtgattgc ttctatcgat ggttcggctt taactgatgt gttagctaaa
    44761 gcaaaagaag cagatatcaa ggtgatcgcc tatgatcgtt tactgatgaa ttcagaaaat
    44821 gtcgattatt acgcgacttt tgataatttt ggagtaggtg tatcgcaagc agcttatatt
    44881 gaagagcact taggattgaa agaaggaaaa ggaccattca cgattgaatt atttggtggc
    44941 tcgcctgacg acaacaacgc actaatcaat tacaacggag tgatgtctgt tttacaacca
    45001 tatatggaca acggtcagtt ggtcgtgcca tctggacaga cgagtttcag tcaaatcgct
    45061 acgcttcgct gggatggttc tacggcgcaa gcaaggatgg ataatctgtt aagcgcaaat
    45121 tatactgacc aaacattgga tgctgttttg tcgccatatg atccaataag tttaggaatc
    45181 atttcgtcat taaaaggcgt ggggtatggg agtgaaagta aacctttacc tgtgattact
    45241 ggacaagatg cgacagttgc tggcgttaaa tcgatcattg ccggggaaca aacacaaacg
    45301 atctttaaag acacacgtat cttagcaaaa aatacgattg aaatgatcaa agcaatcagt
    45361 gatggagaag aggttccggt caatgatact gaaacttatg ataatggggt gaaaactgtc
    45421 cctacgtatt tagcaaatac agtatctgtc gataaagata attatcaagc agagctgatc
    45481 gacaccgatt attataaaga atccgatctg aaaaattaag aggaaccaaa caaggaacta
    45541 aagagatcta agtcagagag aggataagaa ttatggcgga ttgtatttta aaaatggcag
    45601 atatcaccaa aaaattttct ggaatccgag cgttagattg cgtgaatctg atgattgaac
    45661 gtggggaaat ccatgcattg tgcggagaaa acggagcggg aaaatcaaca ttgatgaatg
    45721 tcttgagcgg cttgtatcca tatggctcct atgacgggga aatcttttat gatggaaagc
    45781 tgtgtcaatt taaagatttg aaagatagtg aagaaaaagg catcgtcatc attcatcaag
    45841 aattagcact aagtccttat ctttcaataa aagagaatat ttttctcgga aatgaacaag
    45901 cagaaagagg cgtgattgat tgggaactga cagaaaagaa aacatatgaa ctgctgaata
    45961 aagtcggttt gtctatcgac ccgaatcttc tagtatccca gattggcgta gggcaacagc
    46021 aactagttga aatagctaaa gcattatcaa aatccgtccg tctgttgatt ttggatgagc
    46081 ctaccgctgc attgaatgaa gaagaaagcg cgaatttgct gagattgatc cgagagttga
    46141 aagagcaagg tgtaacctcc atcattattt cacataagct gaatgaaatc gtggatatcg
    46201 cagatcgaat caccatttta cgggatggac agacgattga gacactagaa aatgaaatga
    46261 tcagcgaaga gcatattatt cgcggaatgg tgggcagaga tttagttgat cgttatcctg
    46321 aaagaaaacc ggatattgga gaagtttatt ttaaagtaga agactggacg gtctatcacc
    46381 ctcttgatca cgagcgaatc ataaacgacc acatcaactt gcatttgaaa aaaggagaga
    46441 ttgtaggaat agctggactg atgggagcgg gcagaactga attcgctatg agtctatttg
    46501 gacattctta tggaagcaag atatccggac gtatattaaa ggaaggggca gagatatcag
    46561 ttaagaccgt tccttcagcc attgcaaacg gactcgctta tgtctcggag gaccgaaaat
    46621 ctttaggact gaatctgctg atggatattc gggaaaacgt gacgctgagc agtttggata
    46681 aaataagtca aaaaggagta ttagataaag aaaaagaagt aactgaggca gaaaatttcc
    46741 ggaaaaagat gcgtataaaa acaaactcca tccatcaaat tgtcagtagt cttagtggtg
    46801 ggaatcaaca aaaagtcgtt ttatccaagt ggctgatgac acaacccgat attctttttt
    46861 tggatgagcc aacccgtggg atagatgttg gggcaaaata tgagatctac acgattatcg
    46921 aagaaatggc agcaaatggc aaagctgtct gtcttatctc ttctgaactt cctgaaatat
    46981 tagggatgtg tgatcgaatc tatacgatga acgaaggacg tattacagga gaagtctcgc
    47041 gagaagatgc agatcaggaa gtcttgatga aattaatgac gaaagaagag gtgggttaag
    47101 ttggaacagg caaaaaatct tacggataaa aaagagaaaa aactaaattt gaaaagtaga
    47161 gcagctgatc tttttggtcg ctacagcatg gtgatcattt tagcgggact acttattgcg
    47221 tttcaattga tgacggatgg tattttctgg cgtccattga atataactaa ccttgttctg
    47281 caaaatagcc atatattagt actagctgca gggatgttat tagttgtgct cttaggtcat
    47341 gtggatttgt cggtagggtc agtgatggcg tttgttggtg caattgcggg catgatgatg
    47401 gtcaatcgcc aaatgaaccc gtggatgaca gttatcgcat gtcttgcagt aggcgggctg
    47461 atcggcgcat ggcaaggttt ttgggtagct tatgcaggga taccggcgtt tatcgtgact
    47521 ttagcaggat tgctgatgtt tcgtggactg acacaagttg ttctaggagg ccaatctcta
    47581 gcaccttttc cagctgtttt ccaaaaaatg tctacgggtt atttaccaga cttaagcgaa
    47641 ggaagcagcc ttcacttctt gacattgatt ttaggaatga tcatcacgat cgtgttagtt
    47701 gttggtcaat ggcgaacaag aaatcgtcgg aaaaatcatt tatttgaagt ggaatctcca
    47761 acagctttct tggtaaaggc ggtatttaca gcagtcgttg tactaggaat aacttatatc
    47821 tttgcctctt atcaagggta tccgattatt ttgatcattc ttggtttgat cgttgcagca
    47881 tatgggtttt tgacaaataa aacagtagca ggtcgacaga tttatgcgac gggcggaaat
    47941 cgaaaagcgg ctgaactatc agggatcaaa acaaagcgaa tcacgttctg ggtattcgtc
    48001 aacatgggag tcatggcagc tttagctgga ttagttttag ctgctcgatt gaatgcggca
    48061 acacctcaag caggtacatc gatggaactg gatgcaatgg cggcagtata ttttggtggt
    48121 gcttcgactt ccggcggcat tggaacaatc atgggtgcga ttgtcggtgg cttggtcatg
    48181 ggtgtattga acaatggcat gtcgatttta ggcgtcgggg tagactggca gcaggcaatc
    48241 aaaggattga tcttgctttt agccgttgtg ctagacttgt ataataagaa aaaacgaaca
    48301 acgtaggaga acgccggtta ttcagaaaaa agactgtgac aagacatttg tcacagtctt
    48361 tttttcgcta aaagcgaaca ttcattgttt cgtttgtata gactaaaaat aatatatgtt
    48421 tttttaccat tcgtataaat tctctttttg ctcttgattt ttttgcttaa ttgagttaaa
    48481 ttacataggg cgctaaaaaa agccttgatt aaattaataa tgttcgtgtt ttgctggatg
    48541 tgaacatcag gaggataatg taatgaaagt atttgattac gaagatattc aattaattcc
    48601 taataaatgt atcgtaaata gccgttctga atgtgataca acggtcacat taggtaaaca
    48661 tacattcaaa atgccagtag tgcctgccaa catgcagacg attattgatg aaacaatcgc
    48721 agaattctta gcggaaaatg gttatttcta tatcatgcat cggtttgatg aagcagctcg
    48781 aattccgttt atcaaaaaaa tgaaaaagcg tggattgatt acctcgatca gtgttggcgt
    48841 caagaaagag gaatattcct ttatagagaa gttggcagaa gaatcgctaa atcctgatta
    48901 tatcactatc gacatcgcgc atggacatgc taactcagtt attgatatga ttcagcatat
    48961 taaaaaatat ttgcctgaaa cttttgtgat tgccggtaat gttggtacac cggaagccgt
    49021 ccgtgaattg gaaaatgcgg gcgcagatgc aacaaaagtc gggattggtc caggaaaagt
    49081 atgtattaca aaaatcaaga caggctttgg gactggaggc tggcaactgg cagctcttag
    49141 atggtgtgcg aaagcagctc gcaagccgat catcgctgac ggtgggatca gaacacatgg
    49201 cgatattgca aaatctgtcc gttttggtgc gacaatggtc atgattggtt cattgtttgc
    49261 cggtcacgag gaatctcctg gcgaaacaaa agtcgaaaat ggaatcgtgt ataaagaata
    49321 ctttggttct gcttcagaat tccaaaaagg cgaaaaacga aatgttgaag gaaagaaaat
    49381 ctggatccaa cacaaaggat ctttgaaaga tacactagtg gaaatgcaac aagaccttca
    49441 atcatctatt tcttatgctg gaggaagaga tctggaagcc attcgaaaag ttgactatgt
    49501 catcgtgaaa aattcgattt ttaatggaga cacaatctaa aaaataaata aaatattagg
    49561 atgttgtgaa aaagttgtcc tgcattaagt aataagaaca gccaaacaaa aatagttctt
    49621 tatatgtttt gtttggctgg aattattatc gcagatacaa gcttttgaac atcattattc
    49681 agaataaggg actgtgataa gatttttgtc acagtccctt atgttttgca aaaaaagttt
    49741 ttcttttttc tcgtaaattc ggtaaaatca aaagaaaaaa tagacaatag aaaagagaag
    49801 cttatgtggg aaaaagtaga gaaaaaacaa ggaccgattt atcgtcaaat tatggaacag
    49861 attatgagag aaatcgaaaa cggaaggatc aatcctggaa gtcaacttga atcagaacga
    49921 aaactagggc aactttttgg tgtgaatcgt tccaccgttg tccatgcatt ggaagagctt
    49981 agggagcttg gggtactaac gagcaaacgt ggcagcggat ggtttgttaa tcagactgaa
    50041 tgggggaaat tcgctgttcc aagaatcgat tggcggcaaa tgatctctcc tcgttatgag
    50101 cagacggact ggtatgagca aaaaataaga gaagcaaagc agatccaaaa aacatcgttt
    50161 cttgatttat acgctagcga gatgccagat gagcttttgc cgaattttga gtttccttct
    50221 tattctcttg aagaaatctt agcggaagaa aaagaaatgg atcttttagg ctatactccg
    50281 ttacgtaaca aaatcaaacg gtatttggaa agtaaatttg aattggcatt ttcccccaac
    50341 cagcttcttg tgactggtgg cggtcagcaa gcaatctttt tgattttaca aacgattctt
    50401 tcagctggag aggggatagc tgtagagtca ccttcttttt tttaccgatt acctcttttc
    50461 aaagcttcag gaacgcgttt atttgggata ccgatggatg aagaagggat cgacttagaa
    50521 aaactgaaag aatcgatcca taaaaataaa ttgaaagcag tgcttatcaa cccgaatttt
    50581 caaaacccta caggaaaagt gatgagtcaa aaacgacgag aaaagctagt agaattgtgt
    50641 cgacagtatc ggcttccaat tattgaagac gatgtattta cggatctttc atttctaaac
    50701 caagaagaag tccttcctat acgaacgatt gatccggata atgtgttata cgtcggttcg
    50761 ttatctaggg ttttaggaaa aacaacgaaa atcggttggg tgataggacc tgagactttt
    50821 atctcgcaac tagctcaagc gcaagaaatg atggagtttt cgatgaatat ccttacacaa
    50881 atcacagtgg ctaatgtatt taatgaagca attgatttga aaatgcaaga tgtaagaaaa
    50941 aagttgaaag aaaaaagccg actgataagc gcttggggag attcacaatc gtttttcaag
    51001 cttcattcaa ttttaggtgg ttactatgcc tggattactt gggatgggaa aaaactagac
    51061 cccgaactag cagaaaaagt agtagatatg ggtcttggaa ttgcaccaag tctacttttt
    51121 gggcaagata taaatggaat cagaatcaat tacagtaggc tggatgaaaa ccaaataccg
    51181 ttgttttatt caaagatgaa aattctagaa aagtggttaa cagaataatt tcacaaagta
    51241 aatagattaa agaatataac agcttggatt taaatttcaa gctgtttctt ttttttcgga
    51301 aaaagaatac gatataaaga aactaagaaa aaaccattat ttgtacgtcc gttcacgatg
    51361 tgtaaataaa ataaatgttt gcaacaaaac tgtataacac caacgttttt aaatagaaac
    51421 agatggttgt aagtttgatt agaaaataga aaaaatgcag atgaaatata aaacgctttc
    51481 cttattgtga ttttattcac taatgctgtt aatatgcgga ttggcataat ttcctttcat
    51541 cgtgaaaatt tgtgctttta gcttgtattt ctcataaatc catgataatt tattaatgaa
    51601 gacggttaaa tagtgataca gttttattca ctgtttcaat cgcagaatga agagattttc
    51661 ttatagatga gagaggaatg tgtgacaaat ggcaaacaaa aaagcaccga tcgacttcca
    51721 agcactgcta gatgaagtca atgcagattt cccagtatat caagcacttg atcaagatgg
    51781 aaacgtagtt aacaaagatt tagtacctga tttatccgat gatgaactcg ttgaattaat
    51841 gactcatatg gtatggtctc gtgtattaga ccaacgttca acagcgctga accgccaagg
    51901 acgcctaggc ttttttgcac caactgctgg acaagaggca agtcagctgg ctagtgctta
    51961 cgcatttgat aaagaagatg ttcttcttcc aggttatcgg gatgtacctc aactagtaaa
    52021 acatggttta cctttatctc aagctttttt atggtctcga ggacatgctg caggtaattc
    52081 ttatccggaa gaattgaaag ctctaccacc acaaattatc atcggtgcac aatatgtaca
    52141 agcagccggt gttgcattag gtttgaagaa acgaaacaag aaaaatgtcg tcttcactta
    52201 tactggtgat ggcggttcat cacaaggtga tttttacgaa gcaatcaatt tcgctggcgc
    52261 ttaccatgca aatgccgtat tttatatcca aaacaacggg tatgcgatct ctacacctcg
    52321 tgaaaaacaa actgcagcaa aaacacttgc acaaaaagct gtcgcagctg ggattcctgg
    52381 tattcaagtc gatggaatgg atccgcttgc agtatatact gtatctaaaa tggcacggga
    52441 atgggcgatc agtggaaatg gaccagtcct aatcgaaaca ctgacttatc gttatggacc
    52501 acatacacta tctggtgacg atccaacccg ctaccgtaca aaagacacag atgacgattg
    52561 gcagaaaaaa gatccattga tccgcttccg taaatatttg acggaaaaag gactttggtc
    52621 tgaagaaaaa gaagaacaag tcatcgaagc aactaaagaa gaaatcaaag cagctattgc
    52681 tgaagccgac aaagtaccaa aacaaaaggt ttcagatttc ttgaaaaaca tgttcgaagt
    52741 atctccacaa tcaatcaaag aacaaattgc aatttatgaa gcgaaggagt cgaaataatc
    52801 atggcacaaa aaacaatgat ccaagcaatc acagatgcct tagcacttga actagaaaat
    52861 gacgagaatg tcgttgtttt tggtgaagat gttgggaaaa acggaggagt tttccgggca
    52921 actgaaggat tgcaggaaaa gttcggagaa gaccgagtat tcgatactcc tttagctgaa
    52981 tctggaatcg caggattgag tttcggtctt gcgttagaag gatttcgtcc agttcctgaa
    53041 atccaattct ttggttttat tttcgaagca atggacgaag tagtagctca aatggctcgt
    53101 acaagatatc gaatgagcgg cactagaaat ctacccatca caattcgttc gccatttggt
    53161 ggcggtgttc atacaccaga attgcattcg gataatttag aaggtttgat cgctcagtct
    53221 cctggtattc gagtagtgat tccttccaac ccttatgatg caaaaggact attgatttct
    53281 tctattagaa gtaacgatcc ggttgttttc ctagaacaca tgaaactata tcgctcattc
    53341 cgagaagaag tgccggatga agcttacgaa gttcctttgg ataaagcagc agttactcgt
    53401 gagggaacag atgtatctat tatcacatac ggagcaatgg tgcgtgaagc aatcaaagca
    53461 gcagacaatc ttgcaaaaga aaatatatct gttgaaatca ttgatcttcg tacagttgcg
    53521 ccattagatg tagaaacgat cattcaatcc gtggaaaaaa ctggtcgcgt agttgttgtc
    53581 caagaagcac aacgacaagc gggcgttgcc gcgcaagtag tttctgagat ctcagaacgc
    53641 gctatccttt cattagaagc cccaatcgga cgagtttctg cacctgatac agtcttccca
    53701 tttggacaag cagaaaatgt ctggttgcca aatgcaaaag atatcgaaga caaagtaaaa
    53761 gaaatcgcgg aattttaaga aaagaaggga cgaaacaaag tcatggctta tcaatttaaa
    53821 ttgccggata tcggtgaagg aatcgcagaa ggtgaaatcg tcaaatggtt cgtcaaacca
    53881 ggagatacga tcaatgaaga tgatacatta ctagaagttc aaaatgacaa atcagtagaa
    53941 gaaatcccgt cacctgttac aggaacggtt aaaaatgtga ttgttccaga aggtaccgta
    54001 gcaaatgttg gggatgtatt agtagaaatc gatgcaccag gacacgaaga caatgaaggg
    54061 gacagtggtg tagccgcaga atcccaaact ccagctaaac cggctgctga acccactgtt
    54121 gatacagaat cagctggatc gtcaagcgaa ggagtcttcc aatttaagtt accggatatc
    54181 ggtgaaggaa tcgcagaagg tgaaatcgtc aaatggttcg tcaaaccagg agatacgatc
    54241 aatgaagatg atacattact agaagttcaa aatgacaaat cagtagaaga aattccgtca
    54301 cctgtcacag ggacagttaa aaacgtgatt gttccagaag gcactgtagc aaatgttggg
    54361 gatgtattag tagaaatcga tgctcctgga cacaatagtg caccgtcaac tagtgcgcca
    54421 tcagctgaag caccaaaaga aaaagtggaa acatcaggtt cagcaagtgt cgttgaagct
    54481 gccgatccaa ataaacgtgt attggctatg ccatctgttc gtcaatttgc ccgtgaaaaa
    54541 gatgtagata tctcacaagt aactgcaact ggaaaaggtg gcagagtaac aaaagaggac
    54601 atcgaaaact tcttggcagg tggtccaagc agtgcaccag cgaaatcaga agcgccagaa
    54661 gcggcagcac cgaaagaagc agctcctgca gcagaaagca aaccagctgc accagcaaaa
    54721 ccattcaagt ccaacttagg agacttggaa gaacgtgtag caatgacgcc aacacgtaaa
    54781 gctatcgcta aagcaatggt caacagtaag catacagctc cacacgtgac attgcatgat
    54841 gaagtagaag tgtctaaact atgggataat cggaaacgat ttaaagaagt tgctgctgca
    54901 aatggtacga aacttacttt cttgccatat gtcgtgaaag ctttaacagc gactgttaag
    54961 aaatacccag tattgaatgc atctatcgac gatgcaaacc aagaaatcgt ttataaacat
    55021 tactacaata tcggtattgc aactgatacg gatcacggac tatatgtacc aaatgtgaaa
    55081 gatgcagacc gcaaaggaat gtttgctatt gcagacgaaa tcaatgagaa agcaaaatta
    55141 gctcatgacg gcaaactatc tgcagaagat atgcgcaatg gaacaattac gatcagcaat
    55201 atcggatctg taggtggcgg ttggtttaca ccagtcatca actatccaga agtagctatt
    55261 ttaggtgtag gaacgattgc acaacaacca atcgtaaatg ctgaaggcga aatcgttgtc
    55321 ggtcgtgtga tgaaactgtc attaagtttc gatcaccgta tcgtagatgg agcaactgcg
    55381 caacaagcaa tgaataatat caaacgtctt ttagctgatc cagagctatt aatgatggaa
    55441 ggatgataaa caaatggtag ttggagattt tgctgtagaa ttagatacag ttgtaattgg
    55501 tgcgggacct ggtggctatg tagctgccat ccgcgctgct gaaatgggac aaaaagtagc
    55561 aatcattgaa agagagtata ttggcggtgt ttgtttgaat gtcggctgta ttccttcaaa
    55621 agcactgata gctgcaggac accattatca agagtcacta gattctgaaa tgtttggagt
    55681 aactagtgaa aacgtcaaac tagattttgc aaaaacacaa gaatggaaag aaaacaaagt
    55741 tgtccatacg ttgacttctg gtgttggttt cctattaaaa aaacataagg ttgaaacaat
    55801 cgaaggagaa gcgttcttcg tagatgatca cacactacgc gtcattcatc cagattcagc
    55861 tcaaacttat tcgttcaata acgcaatcat cgcaacaggt tcccgtccaa tcgagattcc
    55921 aggatttaaa ttcggaggac gtgtgttaga ttctactggc ggattagcat tgaaagaagt
    55981 acctaagaaa tttgtgatca tcggtggcgg tgtgattggt gccgaattgg gcggagcgta
    56041 cgcaaactta ggagcagaag taacgattct tgaaggctca ccacaaattt taccaactta
    56101 cgaaaaagat ctagtaaaat tagtagaaga tgatttcaag aaaaaaggcg taacagtcgt
    56161 aacgaatgca atggcgaaag aagcagtcga taacggtgac agcgtgacag tgaaatatgc
    56221 agtggacggg aaagaagaat ccgttactgc tgattatgtg atggtcactg taggtcgtcg
    56281 tccgaataca gatgatatgg gcttagaaca agcgggtgtc gaagtaggag aacgaggatt
    56341 gatcacggtg gataaacaag gacgtacgaa cgtacctaac atctatgcca tcggtgatat
    56401 cgttccaggg gcggcattag cacacaaagc cagttatgaa gcaaaaatcg ctgctgaagc
    56461 aatctctggc aaaaaagtag ctgtagatta taaagcaatg ccggcagtag ccttcactga
    56521 tcctgaattg gcttctgtag gtatgacgat caaagaagca aaagatgctg gtatcgaagc
    56581 aaaagcatat aaattcccat tttcagggaa cggtcgggca ttatcgcttg gtaaaacaga
    56641 aggattcatc cgtctagtta cgacgatcga agataacgtg cttattggcg cgcaaatcgg
    56701 tggagtcggc gcaagtgata tggtctctga attagcttta gcaatcgaat caggaatgaa
    56761 tgctgaagat atcgccttga cgattcatcc tcatccatct cttggcgaaa tcgtcatgga
    56821 tgcttcggaa ttagcattag gtttaccaat ccatatttga tttgaataat acaggcgaaa
    56881 cgcaactgaa aaatcagttg cgttttgttt tttagaatta tcaataatat tattatgtaa
    56941 acttaaaaat atgacaactt cttggtttat taccacttcc tatgctacac tgaagaggaa
    57001 tatgaaatag gagagttgaa gatgcaagaa tatcagtatc cacttgattt agattggaca
    57061 acagacgaaa tggtcattgt aatgaagatg tgggaagatc tggaacgtgc gaatgaaaaa
    57121 gggataaaca atgaagcttt tttgaagact tatcagcagt ttaaaactgt tgtcaaatcc
    57181 attggtgagg aaaaacgatt gggacgggaa tttgaaaaag cttccggtta ttctttatat
    57241 cgtacagtgc agcaagcaaa aaaaaatcca aacaaaactt tgagaatgaa cgggtgagat
    57301 aaatggaaca gatgattgat catatcaagt cctggcttga agaagctggt gagaaaatca
    57361 aatcttctca acaaacatta acaatctcgc aaaaatcaaa tcgaacggat ctagtaacaa
    57421 atgtcgatcg aaacatccag aattttctaa tcgaaaaaat ccattccttt gatccagagg
    57481 cgaaaatatt ggcagaagaa gaagggtgta atcaattatc ggatctcgat ggaagagtct
    57541 ttatcatcga tcctattgat ggcaccttga attttgtgat tgaaggggaa aatttttgta
    57601 ttatgctcgc tgtttatgaa tccggcgttg gaaagcttgg tttcatttat gacgtgatga
    57661 gaaatgaact tttttggggt ggaaaaggaa taggcgtgta taaaaatgat gagccattgc
    57721 ctagaccagc aaataaatcc ttatcggaag gcttacttgg tgtgaatagt tatcttttcg
    57781 gtcataataa atatggaatc cgagaaattg cggaaagcag catggggaca cgtatgtacg
    57841 gatgcgctgg tcttgaacta gtggcaatct tgaaaggaaa ccacattgct tatatttcaa
    57901 accttagccc ttgggattat gcagcgggaa atgtcttatt ggaagagttt ggtatggtaa
    57961 caagcggtct ttttggtact cctttgacat ttgaaaaaag ggaatactat ttagcaggga
    58021 cttcttgtgc atatgcagaa atcgcagacc ttttgaaaaa agaaggctga aaaaaaggta
    58081 gaaatcattc acaaaaatga taaaaacgag caaaagatta attttctcga aaaaatgaaa
    58141 acattttact atatttcatg aaaaaagtct gctataatta gcagtcgagt aaaatttgcc
    58201 ctgtcataaa gaaccaataa aaaaggagtt agttacattg aattatagaa acgatatccg
    58261 taacgtcgca attattgccc acgttgacca cggaaaaaca acattagttg atgaactatt
    58321 aaaacaatca gatacattag acgcacatac gcaattgcaa gaacgtgcga tggactcaaa
    58381 tgcgctagaa aaagaacgtg gtatcacgat tttagccaaa aacacagctg tagactataa
    58441 aggtattcgc gtaaacatca tggatactcc aggacacgcg gacttcggtg gcgaagtaga
    58501 acggatcatg aaaatggttg acggcgttgt gttggtcgta gatgcgtatg aaggaacaat
    58561 gcctcaaaca cgttttgtat tgaaaaaagc actggaacaa catatcacac caatcgttgt
    58621 cgtaaacaag attgacaaac cttctgctcg tcctgagcat gtcgtagatg aagttcttga
    58681 actattcatc gaattaggag cagatgatga tcagttagac tttcctgtga tttatgcatc
    58741 tgcactaaat ggtacgtcaa gcttgtcaga tgatccagca gatcaagaac caaccatggc
    58801 acctattttt gatacaatta ttgaaaaaat ccctgctcct gtcgataaca gcgacgaacc
    58861 attacaattc caagtttcat tacttgacta caacgattat gtaggtcgta tcggaatcgg
    58921 acgtgtattt agaggaacaa tcaaagtagg agaccaagta gcattaatta aattagacgg
    58981 aacagttaag aaattccgtg taacgaaatt atttggtttc tttggactaa aacgtctaga
    59041 gattcaagaa gcaaaagctg gagacttgat tgctgtctca ggtatggaag atatctttgt
    59101 cggtgaaaca gttactcctg tggatcatca agatgcgtta cctatccttc acattgacga
    59161 accaacattg caaatgactt tcttagttaa taattcacca tttgccggtc gagaaggtaa
    59221 attcgtaacc gctcgtaaga ttgaagaacg tttgatggca gaacttcaaa cagatgtatc
    59281 cttacgagtt gaaccaacaa actctccaga tgcatggaca gtttctggtc gtggagaatt
    59341 gcatttgtct atcttgattg aaaacatgcg ccgtgaggga tacgaattgc aagtatctcg
    59401 tccagaagtt attgaaaaag aaatcgacgg tgtaaaatgc gaaccgtttg aacgcgtgca
    59461 aatcgataca ccagaagaat atatgggtag tgttatcgag tccttgagct tacgtaaagg
    59521 tgaaatgcaa gatatggtcc atacaggaaa cggacaaatc cgtttgacat tcttaacacc
    59581 tgcccgcggt ttgattggtt attcaactga attcctttca atgacacgtg gttacggaat
    59641 catgaaccat acttttgacc aatatctgcc aatgcttcct ggtcaaattg gcggacgtca
    59701 ccaaggggcg cttgtttcga tcgatacagg aaaagcaacg acttattcta tcatgagtat
    59761 cgaagaacgc ggtacagtct tcgtagaacc aggtacagaa gtatatgaag gaatgattat
    59821 cggggaaaac agccgtgata atgatttgac tgtcaacatc acgaaagcaa aacaaatgac
    59881 aaacgtacgg tctgctacta aagaccaaac atctgtcatc aaaaaaccaa aacaattgac
    59941 gttggaagaa tctttggaat tcttgaatga tgatgaatat tgcgaagtaa caccagaaag
    60001 cattcgcttg agaaaacaaa ttttagagaa aaatgctcgt gaaaaagcat ctaaaaagaa
    60061 aaaataatct gtaaaaggat gaagagagaa accagcttgt tataaaaaat agctggtttc
    60121 tttttttgtc caactctttt ctgtggagaa gtcatctttg tcaatggaca taaattcaga
    60181 aaatacgccg aaagacgttt aaaagacttt taaaaaactt atttctagag agtttttgtt
    60241 tcataataag ataatgtttc acgaaaggag atcaacttgt ccttcgaaga aaatcgaagt
    60301 aaaatggcaa gagaaaggag cgggaagatg aacgacttat taaaacaata ctttggctat
    60361 gatgagttta gacctggtca aaaagaaatt atccagaaag tcattgatca ggaaaatgta
    60421 ttaggaatca tgcctaccgg aagtgggaaa tcaatctgtt accagcttcc agctttacta
    60481 ttagatgggc ttactgtggt tgtgtcccct ttaatctctt tgatgaagga tcaggtggac
    60541 gcggcgaatc aattaggtat acccgccact tttatcaata gctcgttaga tggttacgaa
    60601 acagctagac gcttccaaga aatcgataga cagcagtacc gtttacttta tatcgctcct
    60661 gaacgtttta tcatgccgga ttttatccaa gcaatgaagc gatggaacgt ccgtatgatc
    60721 gctattgacg aggcacattg tatctctcag tgggggcatg atttccgccc aagttattta
    60781 cagatggcga accagctaga tcaactgcca aatcgtcctg taattgttgc tttgacagct
    60841 acagcgactg tgcaagtagc tgctgacata aaaagacttt taaaaattcc agaaaacaac
    60901 catattcaga ctggttttga acgagaaaat ctacgatttc aagtaattaa agatcaaaaa
    60961 aaagaacaat atctaatcga atatttaaag atcaacaaaa atcaatctgg tatcatttat
    61021 gcagcaacga gaaaagaagt agaccgtctc tatcatttgc ttaaaaaatt cgatttttcc
    61081 gtgggtagat atcatggtgg tctaaatgag aatgagcgaa cagaaatgca agaagccttt
    61141 ttatacgatc gcttgcagct gattgtagcg acaaatgcat ttggtatggg tagaaataaa
    61201 agcaatgtcc gttttgttat ccattatcaa attcctggct ctctagaagc atactatcag
    61261 gaagctggtc gggcgggaag agatggtctt tccagtgaag ccatcctgct tttctctcct
    61321 caagatatcc aagtccaaaa gttttttatc cagcagtccc aaagagaaga agggcaaaag
    61381 caaaaagaat atgaaaaatt aaaagcgatg acagaatacg tgtatattga gtcctgtctt
    61441 cagcaataca tcctaaacta ttttggcgag acaagcagtc cgtgcaaccg ttgtggtaac
    61501 tgtttagatg acagagaaat agtagaagta acgacagaag cacagatggt tctttcttgc
    61561 ttaaaacgta tgggtgagaa ctatggtaaa caaatgctga tgaaagtctt agcaggatcg
    61621 aaagaacaaa agctgcaagc tttaggtttt ggacatttat ctacctatgg actgatgaaa
    61681 aaccaatcgc aaaaagaaac gatgcagtta attgaatatt tgatatcgaa tggctatctt
    61741 ctgaccatca atggtgagta tcctgttttg aaagtaacag aaagagggat acaagtattg
    61801 aaaggacaag aatctgttta tcgaaaggaa cccaagaaag tccagcagct atcggatgaa
    61861 gaaaccgata cactatttga agtgctgcgg gaactgcgaa cggatctagc atcagaagca
    61921 ggcgttcccc cgtatgtcgt attttcagat tccacattga aagaaatgag ccgaatacgt
    61981 ccatcaagca gattggagat gcttcagata aaaggagttg gccaaagcaa gcttgataaa
    62041 tatggcgaag cctttttatc tcggataaaa aatgcggact ctaacgttct ggataagtag
    62101 aaagaacgaa tacgtaaaaa tgaataaaaa caactggtta aatctgtttt ttttgctcct
    62161 tatgaaaatc aaatatgtta taattaagga attagaatgg gaggtaagca cagatggatt
    62221 ctttgtcgaa aaaacttgcg atccaagtat taaatgatga agcagaacgg atcaaacgat
    62281 taatccgaaa tcaaaacaac agtctctgta tctcacaatg caaagccttc gaagaagtgg
    62341 tagatacaca gatgtacggc ttttcccggc aagtcggttt tgctgtccgt ataggagtaa
    62401 tcggaaagaa cgagggccag ctgatgttaa gtgagctaga acgagaattg aatcagttat
    62461 atagtgaggt ttaccaagaa atttatgata aaaaagaagt tggcaaggag gaatagactt
    62521 gcctaagaaa gtgaaaaaaa ggcatctatt agactatagc atcttgattc cctatttaat
    62581 tttatgtgta ttgggattga tcatggtata tagttctacg tcgtatctat tattagaaaa
    62641 cggacaaaat ccgtccgcat cagtcattaa ccagagtatt ttttgggtgc ttagcttgat
    62701 tgctatcgca ctactttata aaatgaaaac agatgttttg aaaaaccagc gtttgatcat
    62761 ggcagccatc gcagttttga cgattttgct gctgattgtt gtgttttttg gtaaggagat
    62821 caatggggcg aaaggttggc tgcaaattgc aggattctcg atccaacctg ccgaatacct
    62881 aaaaatcatt tctatctggt acctgtctct gactttatct aaaagacaaa acagtgtaca
    62941 aaaagatttt cttgggactg tgaaacgtcc acttgcaatg gttatcggac ttactgcatt
    63001 agtcgctatt cttcccgatt ttggtaatgc ggcagttatc tttttgatta ttttggttct
    63061 gcttttagcc agcggagtca attatgtgta tactttgatt gtaggagtag gaggcttttg
    63121 tctaagtact tttacgatct ggctgatcaa tatcacaaac ggaaagatct tacccggacg
    63181 tttacagtat atctataatc gatttgctat ttaccaaaat cctttctcag acgaattaaa
    63241 taaagggcat caactagtca acggctacta tgccatgttc aacggaggac tatttggcag
    63301 gggattaggt aacagtatcc agaaaaaagg atttttacaa gaagcacaaa ccgattttat
    63361 ttatgcaatc gtagtggaag aactgggagt gattatgggg attttgatat tagcgttgct
    63421 attctttatg attgtgcgca ttgtccttgt aggtatccgt tcaaaagatc cgttcaattc
    63481 gcttttgtgc attgggatcg gcgcaatgtt tttgatccaa gtatttgtca atcttggagg
    63541 aattactggc gttattcctt tgacagggat cacgttccca tttttaagtc aaggaggctc
    63601 cagtttgctg atgctttcga tttgtgtcgg ctttgtcctc aacatcagtg cggatgaaaa
    63661 acgcaagagc ttaggtttat aataaaaaaa gatgtaggag tggttcgatg aaaaaagttt
    63721 tagttgctaa caggggtgaa atcgctgtac gtgtatttcg tgcttgtaca gaattaggaa
    63781 ttaaaactgt tggaatctat gcagaagaag atgaatattc cgtacaccgt ttcaaagcgg
    63841 atgaagcata tttagtagga caaggaaaaa aaccgattga tgcgtatcta gatattgaag
    63901 ggatcatttc tatcgcgaaa gaatgcggag ctgacgctat tcatccgggt tacggtcttt
    63961 tgtcggaaaa cttgaatttt gcgcaacggt gcgaagaaga aggcatcatt tttgttggac
    64021 ccaaactgca tcatttagat atttttggag ataaaatcaa agcaaaagct gcagctatcg
    64081 aagcggggat tgcttcgatt ccaggcacag atggaccaat cgcttctata gacgatgcct
    64141 tggagtttgc gaaacaatac ggttatccga ttatgatcaa ggcagctcta ggcggcggcg
    64201 gacgcggcat gcgtgtagct cacgatgaaa agagtgcaag agagggctac gaacgtgcga
    64261 aaagcgaagc aaaagcagcc tttggtagtg atgaagtgta tgttgaaaaa tacatcgcta
    64321 atcctaagca tatcgaagta cagattctcg gggatacgca tggaaacgtc atccatcttt
    64381 ttgaaagaga ttgttctgtt cagcgccgtc accaaaaagt agtagaagta gcgccttgtg
    64441 tctctatgaa tgaacagcaa cgtcaaaaaa tctgccaggc agctgtccaa ttgatgaaat
    64501 atgtcgggta tgtcaacgca ggtacagtag aatttcttgt tgaaggagat gatttttact
    64561 ttatcgaagt caaccctcgc gtccaagtgg aacatacgat cacagaaatg attacagata
    64621 ttgatatcgt aacaacgcaa ctgttgattg ctcaaggttt ggatctgcat aaagaaatcg
    64681 gattgcctca gcaagaagga attaaattaa atggttcagc cattcaatgc cgaatcacta
    64741 cagaagaccc gttgaataac tttttaccag acacagggaa aatcgatacg tatcgttcac
    64801 ctggtggttt tggcgtacgt ctggatgtcg gaaatgctta cgcgggctat gtagtgacac
    64861 cgtattttga ttcattgcta gtaaaagtat gtacgcatgg tgctaccttt gaaacagcca
    64921 ttcagaaaat ggaacgttgc ttgaaagaat ttagaatccg tggagtgaaa acaaacattc
    64981 catttatgct caatgtcatc acacatcctg aattccaatc aggaaatgca aaaacaacct
    65041 tcattgatag tacagcaaca ttatttgaat ttcctcgact acgagaccgc ggaaacaaaa
    65101 cgatgaaata tatcggtgaa attactgtga atggttttcc aggtatcgaa agtggcgaaa
    65161 aaccatttta tgaagaacca cgtatgccta aagatctaat cacaagaact gattacgtaa
    65221 cggctaagaa tgtattagat gcgaagggtg ccgatgcttt ggtcgaatgg atcaaaggac
    65281 aggaaaattt gttgttgacg gatacgacat ttagagacgc ccatcaaagt ctgctagcaa
    65341 ctcgtgttcg gacaaaggat ttcaagcaga ttgcacgttt gactggagaa ggtcttcctg
    65401 aactcttttc aagtgagatg tgggggggag caacatttga tgtggcttac cgctttttga
    65461 atgaagatcc ttggcaacgg ttgagaaaaa ttcgttcttt aatgcctaat acgttgctgc
    65521 aaatgctttt cagaggttca aatgccgttg ggtattctaa ttatcctgac aatgtattgg
    65581 tggaatttgt caaagaagca gcagcgcaag gaatcgatgt atttcgaatc tttgatagtt
    65641 tgaactggac tccacaaatg gaaaaaagta tccaagctgt acgggatact ggtaaaatcg
    65701 cagaggcagc tatttgctat actggcgata tcaacgatcc aagtcgggca aaatacaatg
    65761 ttcagtatta taaagacatg gcaaaggaac tagaacaact gggtgcgcat atcattgcaa
    65821 tcaaagatat ggctgggctg cttaaaccgc aggcagctta tcgtttgatt agtgaattga
    65881 aagaaacgac agatctgcca atccatctgc atactcatga taccagcggg aatggaatca
    65941 tcacttattc tgctgcttca aaagcaggag tagacatcgt tgacgtggca atgagtgcaa
    66001 tgagtgggaa tactagtcag cctagcatga gcagcttgta ttatgcactg gtcaatggtc
    66061 cacggctgcc agaaatcacg attgaaaatg cacagaaatt aaaccattat tgggaagatg
    66121 tgcgcatgta ttacaaaccg tttgaaaacg gcttgaatgc tcctgaaaca gaagtatata
    66181 tgcatgaaat gccaggagga cagtattcga atctacagca acaggcaaaa gctgtcggat
    66241 taggtcatcg ctgggatgaa atcaaacaaa tgtatcatac tgtcaacttg atgtttggcg
    66301 atatcgttaa agtaactcca tcatctaaag tagttggaga tatggcacta tttatggtcc
    66361 aaaatgatct tacagaagaa gatatttatg aaaaaggcga aacactaagt ttccctgaat
    66421 ctgttgtgac tttcttccaa ggagaactag ggcaacccgt tggcggattt cctaaaaaat
    66481 tgcaaaagat tattcttaaa ggcagacctg cattgaatga acgtccaggt cttttggctg
    66541 aatcagtcga cttcaacgaa gtaaaaaaag aattggcaga aaaaattggc tatgaaccaa
    66601 aacaagacga agtattaagc tatttgatgt atccgcaagt ctttttggac tatcaaaaag
    66661 catataatca atttggcgat gttacattac tggacacacc aacatttttc caaggtatac
    66721 gtttgggtga aacaatcaat gtacaaatcg aacgcggaaa aacgcttatc attcgtttag
    66781 atgaaatcgg agaacccgat atcgaaggga atcgcgtact gttcttcaat ttgaatggac
    66841 aaagacgtga aatcactatc aaagataatt cgatcatcag tacggtccaa acccgattga
    66901 aagctgaacc gacaaaccga gaacaaattg gagcaacgat gtctggttct gttttggatg
    66961 tattagtgaa aaaaggcgat aacgttaaaa aaggtgatac gttgatgatt actgaagcga
    67021 tgaaaatgga aacggccatc gaagcacgtt ttgacggaga agtcgcacat gtatatgtgt
    67081 cttcaggaga cactatttcg tctggtgacc ttttgattga agtgactgag aaataataag
    67141 cgaaaggtgg ggaaacatga aaagactggg tttgttttgg ctgattctgc tattagttat
    67201 tgtggcattc tacatggaac cagtcttgtt tccgccaaaa cttgaagtga aggaaaactc
    67261 tgatcaacaa atatcaaacc aaatgacaac gtggaaatac caggagctta aagcaactgg
    67321 tttttctact tatatcggaa aaccgatcga tcagctggaa aaggattttg gccaagccta
    67381 tgatcgatta actagcggat ttggttttga aacaagatat tatgaaaata aagctagtca
    67441 tctcacattt gaagcgaaca tccaagacag cagagtcaca actgttaaag tactgcaaac
    67501 agggcctgct gatatcgcgc cgttttattt agggatgacg atgcaagatc ttacgaaaat
    67561 cactactatc tatactaatt tcacttttga gtaccatgat acagaagttg gaatcgaact
    67621 aatggaagag gatatgaatt atcgtccgct aattgctttt gataacgaca cttttgctat
    67681 tttatttttt gatcaaacaa caaacggcct attttcagtt gtgtatttag ataaagatag
    67741 tcttttgaaa ctattgccat atcaagtgtt tggtgaaggc cttccacatt atcaagcaga
    67801 taaatcggct gattgggaat caatcaatcg cgttaaagaa cgaaaaagta cgactttatt
    67861 aaatatgctt agaagagaag acgaacttcc catatacaat caaacacttg cctttcaaaa
    67921 ccacagtcag ctgctactac atgatttttt gacaaggcct gaggaaatat tgtcagagga
    67981 acgtatggct gattggcaaa aatcgctagg cagtgctcaa acgacagtga aattctcact
    68041 gacgaatgat gaattggaga agttaatcag taaacaaaaa ttagaaaata ctagtgggct
    68101 atttattcat ccggcgattg acgctacttt ttcgttttta tattggtaca gcgatcctta
    68161 caaccatgac cgtttcatgg acccgggaac ggattctgta ggcattgctt tttctaaaga
    68221 aaatatgtta gtcttattgc aagaagaaaa cggagaaagt agtgatagca gtgatcgtta
    68281 acgaagagct gtttcaactg gaggatcaat gcctccaagt cgctgaaatg ataaaaaaga
    68341 gtaaaacgat ggcttcttat cttgaacata aacagtcaat ggaagaatct gcaaaagttt
    68401 gccagttgaa agaagcgttc ttgtctaaga aagaagcatt tgaaaatgta gcggcatatg
    68461 gtgagtatgc acctgattat cgtgaaaaaa aacgagctgt tcgaaaagca aaaagacagc
    68521 ttgatatgga tgagcatgtt gcagctttcc gatatagtga aacacagctg caaagtctgt
    68581 tggatcaaat tgtccaagta cttgccgaag aagtttctaa tgaaatcaaa gtagatgcag
    68641 gtagcccgtt ttttgaaacg aaaaaacact ttggatgcgg aggtaattgt catgcaatta
    68701 gacaatagtg aatttgaaat aacaaaacga cgcgggctga tcgtatgggt ctacagctta
    68761 aaacaattaa agaatctgaa aaagttcggc ttgttgcatt atgtctcaag aagaatgaaa
    68821 tatgtcgtgc tttacttaaa tgaagagaca ttggaagaaa cagaagaacg aatccgtaaa
    68881 ttacattttg ttcgaaacgt agaacgttct taccgaccgg atatcgaaat gaattttgcc
    68941 gaaaaaatag gaaacaaaac agtattaaaa gacgaaggtt tcgaaattga agagctaaat
    69001 acagaaatcc gattagctga acatctttaa aaatctctta tgagcagttt ttaaataaaa
    69061 aataacttgg ataacgatcg atttttgatc attgtccaag tatttttttg gtatactagt
    69121 accagtacca tttctaagga gtgagtagat gcggataata tcaggaaatt atggcgggcg
    69181 ccgtttaaaa agtttagcag gggcgaacac cagaccaact acagataaag taaaagaatc
    69241 catattcaat atgattggac catattttga tggagagaca gtattggatc tgtttgcagg
    69301 aagcggtggt ttagctatcg aagcagtatc tagaggctgc agtcatgcgg tatgcgtaga
    69361 caaaaattac caagcgctaa aaatcatcaa agaaaacatc gaaattacga aagaaccaga
    69421 gaaatttacc acaataaaac ttgatgcgga caaagcaatc gaacggctag cagcggagaa
    69481 acaacaattc gactacttgt ttcttgatcc gccatatgca aaacaaaaaa taatcgatca
    69541 aatccataaa atggaagaac tgggactttt ttctaaaacc gcagttatcg tatgcgaaac
    69601 ggataaaaca gtcgaattgc cagaaactgt ggctggattc catcaaataa gaaaacagat
    69661 ttatggcata acggccgtaa ctatctatag aaaagaggga aatcaatgaa acgtgcatta
    69721 ttcccaggaa gttttgatcc ttttacaaaa ggtcacttag atacggtgga acgtgcggct
    69781 aaattattcg atgaggtagt aattggtgtt tttatcaata cttcaaagaa aagtttgttt
    69841 cccccagaag aaagaatgac attgatcaca aaagctgttt ctcatcttcc taatgtaaaa
    69901 gtcatgcatc aagaaaatca attgacggta gaaacagcaa aagagattgg tgcagatgcg
    69961 ttgatcagag gcatacgaag tatcaaagac tttgaatatg aacgagagat tgctcagatg
    70021 aatcatcatc tatatgatga attggaaact gtcttcttat tagcaaaacc agaatatagt
    70081 cacgtgagtt ccagtatttt aaaagaagta ctgcactttg gcggagatgt gagcagctac
    70141 ttaccgccag tgatcaacga agctttagct ggaaagcgtg aatcaaatga aagctaaaca
    70201 atggttgaaa acagtactga ttatcatatt tggaatgttg atcattggat ttgtagtagt
    70261 tcccttgccg tattatgtag aatcaccggg agccacgatc gatctgaaag aactaattac
    70321 ggtcaatgat aaggaagata aaggttctgg gtctttctct cttacctctg ttggtatcag
    70381 gcaagctaca ggtttcttag ctttaaaagc taaaatgacc ccttttgaag aattgatcag
    70441 tgaagaagaa ttgactggtg gggcgacaaa tgaagaatat aatcaaatgc aacagtatta
    70501 tatggattct tcccaaaatg cagcaatcga acaagcgtta aaacttgcag acaagcctta
    70561 taaaatggaa ttcaaaggcg tatatgtcat gagtgtagag aaaacatcga atttctttgg
    70621 caagctttca gttggagata cagtaacaaa agtagacggg aaaagctttc aaagtacaga
    70681 agcatttatg gattatgtaa aaagccaaaa agttggacaa acaatcgaaa tcagttattt
    70741 gcataatggt gaagaaaaaa cagcttctgg tgatctgatc gagttaccaa cagataaaaa
    70801 ggcaggaata ggtatcacgc ttactgacca taccgagatc gaatcagata cagatgttcg
    70861 tattaattct ggctctatcg gtgggccatc agcgggattg atgttcactt tagaaatcta
    70921 tgaacaagtc actggtaaaa acttgcgaca tggtaagcaa attgcaggaa ctggaacgat
    70981 caacagtgaa ggagaagttg gccgaatcgg aggaatcgat aaaaaagtgg caagtgcgga
    71041 taaagctggc gtagagattt tctttgcacc agatgatacg atttcagacg atgttaagaa
    71101 agaatatcct gaaataaaaa ccaactacga agaagcaaaa gctgccgcta aaaaattgaa
    71161 ttcctcaatg aaaatcgtac cagtaaaaac agtacaagaa gcgcttgact atctagagaa
    71221 aatgaaatga aactaaataa ttaaagaggg gttgtgacac gagttctgtc acaacccctc
    71281 tttttcgtca aaaatcttca cgataaaaat aaaaacaaaa gaaaaaattg acgtaattag
    71341 atgttgaagg gacgattttg ccagagctca ctgtttcttc aattttaaat gaaaggagta
    71401 atgaatgatt tttactggtc attctttgaa aaaagaacaa tgatagaaaa aatcagcaag
    71461 aaaatactag cttcacccaa attgatcatt tggatgtcta tgatagttct tatcttttgt
    71521 atcgcaagtg gttttttatt atcaaatttg ctattttata gagaaacaga agagactgct
    71581 gcaaaagaaa tactttcttc gtttagttcc agtggagaag atccatcagc tgaaggaaac
    71641 gatgtagaag aggatgctcg tccaaaggtc atgtacaccg atatcaaagg aagtgtgaag
    71701 gagcctggta tctattcctt ttcttcagaa gaacgggtct atgatgtact aaagcgtgca
    71761 ggtggattat tagaagaagc ggatagcgat cgaatcaact tttctgcgaa gatagaagat
    71821 cagcaagtcc tatatatccc tgctgtaggt gaagagctgc cagaacatct tgatcagttg
    71881 gcatcctcgg aaggaaaaca gcctacagca gattccgagc ctcccaaaat aaatatcaat
    71941 acagccactc catcagaact tcagcagatt cctgggatcg gatcagtcaa agcgcaagaa
    72001 atcattcgat ttagagaaga aaacggatcc ttccagaaag tggaagacct gcaggagatt
    72061 tctggtatcg gtgaaaagac agttgaaaaa ctaaaaaact tcgttacaat taaatagaat
    72121 gattcaaaat cgactggcac gagcaataaa tggacgctaa tggatactaa gaataatcca
    72181 attctaagag cttggcagga cgaggaggta gtatttttgg ataggaaata gcttgattgt
    72241 tcgcaaagaa acattaaaaa aaccaatgct gaatgtctat ctccaaaata aaatatctgg
    72301 gattcatatt atgaatacgg ctgtcagcgg caataacagt caagctctac gagaacgctt
    72361 tgccaaagat gtacttagct atacagcaga taaagtattt attctcattg gcacgaatga
    72421 tctagcagag cataaacaac tttctaaaga aacgtaccaa aaaatctgca gtggatgata
    72481 gttcagctga aaaaagacta tagttctgat catgctttct ttatcacgcc accagcagtc
    72541 gatgagacaa aacaaaaata tcggaataac aagttgatca aagaatatat ctctgttctc
    72601 acagaagtag caaaacgcca tgattgtgaa gtatcgattt ttatacggaa tttcttgaac
    72661 aaatggattc gaagaatttt tataatgggc taatggatga cggacttcat ttcggcagtg
    72721 aagggtagga tcttttgtca gacaggatga ttcgttatat ttaaagaata ttttgtttaa
    72781 gcaatgagta ctttttaatc aacttgaaaa aacggaggaa tataaaacat gttagaaaaa
    72841 tcttcaaaag catgcgatac gaataaagaa aaagttactg ataagtcaca taatgaacgc
    72901 attccttggg accagtactt tatggctcag gcagtactgt tatctttacg tagtacgtgt
    72961 acacgtttag aagtaggagc gacactcgtt cgagaaaaaa ggatcattgc tggcggctat
    73021 aatggagcag tcagtggaga tgtccactgc atagatgaag ggtgttacgt cgtggatgga
    73081 cactgcttgc gaacgatcca tgcagagatg aatgcactcc tacagtgtgc aaaacttggt
    73141 atcccgacgg aaggttcaga aatctatgtc acacattttc catgtttggc ctgtacaaag
    73201 gctttgttgc aagctggtgt gaaagggatc aattatctcc atgactatcg aaatgatcct
    73261 tatgcccaag cgttgatcga acaattaggt gtatctgtac accaagttgc tttagactca
    73321 cagcattttt caaaacttca aaatgaatta acaggaaaac atgtctagcg ttttagaaag
    73381 gcatgttcga aatcggttga tttttccggc aattacgtcg atgattatct gtttgttgta
    73441 ttacactgac aattggggtt atcgtttgct tcttgccgga atttttttat ggttttcgct
    73501 aaaagaagga cgttttatcg cgtacttgtg tattttgtgt agcataacgg tatccatttc
    73561 ttataggcta caagagtatt catttttaga ggaaaaaaca acatctgcgc aaattactgt
    73621 atttacagat acgattcgtg caaatggtaa ttttttgaca atggaaggaa ggttatcaga
    73681 gaataaacaa aagctccagc tttcttatca agtaaacaca gaagcagaat tgaaaacatg
    73741 gcttaacttc cgaggaaagg gaatagaatt gactgctgaa ggcgagttca tctctccagc
    73801 aaaaaagcgg aatctttata attttgacca agaagcttac ttcaggaacc atagaatttc
    73861 tggacggttc caaattcaaa agattgaaca gatcaccatg caaaatcact ggcgaaactg
    73921 gcttcagaga aaaagaggat cttttatctc ctttgtccaa tctgaatttc cgcaaaaaac
    73981 aagtgtatat attaattctt tattatgggg ctataaagat gcaggattca gagaaccaga
    74041 agaaattttt agggagagtg gtttgctgca tctgttcagt ctatcgggtc tacacatcca
    74101 attttattta gggtggctgt attatttatt tcgacgtatc ggatggccac tacacgtcag
    74161 tattattccg ttgagtctac taactatctg ttatgtttct attgcaggaa gttctatttc
    74221 tgttttgcgt gctagtttgc tgtttttatt gcgattgcta gtcaaattgc tgaataagca
    74281 ttattccacc atggacttat ttgcagttgt cttttggctt cttttactat ttgatcctcg
    74341 atttcttttt catgcgggtg gacagcttag ttttttcatg agttttttgt ttatcctgat
    74401 ttcttttgat ggagattggt tgaaaaaaac ggcctctcac gtcctgttta ctatgatcac
    74461 gatgccgttg attgtatggc atttttatga gtggcctatt ttaggtagtc tttttacatt
    74521 actgattgca ccggtattca agtttctttt tcttcctggt gtgttatttc tcacactctt
    74581 caatcgctgg ctgccggaaa ctttactttt gttgatagaa gagggattaa tcttatttga
    74641 gcgaataatc gatttttctt cagggtcgtc tctcattata ggacgtttgc cccttgtgct
    74701 atctgggatg tatattttcg gattactgat ttgtatggat aggttgaaag aacaacctgt
    74761 gaaacacttg ttttatgttg gtcttttttc ttttattttt ttgactttgc catttttacg
    74821 cttttcttca acgatcgctt ttatcgatgt cggtcaagga gacagtatct ttttgcaaag
    74881 tccttttcga aaagaaacga ttttgatcga tactggaggt cagttacact ttgaaagaga
    74941 aaagtgggcg caaggtatga tacgtcctcc tgctgaaaga aatatcgttc catatctaaa
    75001 aggtcagggg ataagtgtaa tcgataaact catcttgaca cacgacgata cggatcatgt
    75061 gggagaatta cccacgttat ctcagcattt tactatcaaa aaaatttata tcggttgggg
    75121 cgctggacga aatgagccat tacaaaggca tttatctgaa gctcaaaaaa atggtactga
    75181 gatcattgaa atcaaacatg gggacaggat cagcggttat tatgatcttt atgtattgac
    75241 tccttttgaa aagggagagg gaagaaatga agattcgatt ggtctatgga tggaatataa
    75301 caataggcgc tttttatttt taggagattt gaatcaagca atggaaaaac aattgctttt
    75361 gatttatcct aatctgaaag ccgatgtagt caaattaggt catcacggta gccgtacgtc
    75421 aagtaacaca gattttcttt cccatattga agcaaaacat gggattatat cctgcggcgt
    75481 aaataatcgt tatggtcacc cgcacagcga agtattggag acactagaag aaaatcagat
    75541 aaaaacatgg cgaacggatc aacaaggaat gatcacctat cgctggcatc cagtttttca
    75601 tcctcatggg ctagtggaaa caatgataga ctagtaattc tcatctgctc atggtaggat
    75661 aatttttgaa agtggtgagt aatttgagta tacaagcaga gttacaaaaa atacgtaaag
    75721 aaaaacttgc atcttgttac ttgattttag gaacagaaaa gtttctccaa gatcaagttc
    75781 ggacagaaat tgtcaaaaaa atccaattag agggcgaaga tgacttaaat tttttaagtt
    75841 ttgacatgga aaatgcaagt ttagatgagg tagtagctga agcagagacg ttgccgtttt
    75901 tcggagatca acggttagta ttcgtagaga atccttattt tttaacaggt gaaaaagtaa
    75961 acaatggaat cgaacaaaat actgatttat tgacggctta tttgaaagaa ccattagaat
    76021 cgactgtatt agtattcttt gcgccatatg aaaagttgga tgaacggaaa aaagtaacga
    76081 aacaattgaa aaaaacagca attatcatca atgtccaaca gttgaatgaa aaagaagtac
    76141 gtcaatatct gatgaatacc ttagagaatt cctcaatcaa aatggaacga agtgcaattg
    76201 atttattctt gaggttgacc gacttagatt tatccaaaat gatgagagag ttacagaaat
    76261 tggtccttta tggacaaaat caacagcaaa tcacggtaag agaagtagaa gaattagttc
    76321 ctaaaacgtt agaacataat atttttgaca tgacccaata tattttaaaa gggaagacgg
    76381 aacaagcttt gcgtttatac gaagatttag ttatgcaagg ggaagaaaca atcaaaatta
    76441 atgcgatttt gctttctcaa ttacgtttat ttttacagac aaaatttctt gtaaagattg
    76501 gttatcagca ggcaaatatt gctgaaacat tgaaaatcca tccatatcgt gtaaaacttg
    76561 ccatgcagga agtaaaaaaa ttcgatgaac atttgctggt acagttgttt gatcaattag
    76621 ttgagatgga ttatcaaatc aaaacgggac aaatcgaaaa agaattaagt tttcaactat
    76681 tcgttttgcg cacagggcag ttgttaagaa atcgataaga agaaagacga gggcaaagca
    76741 tgcgggaagg tcgtttgttt ttgtcctttt tttgacaaat aaaaaaatcg gccgaagccg
    76801 attcttttat ttagcgattt ttttgcttaa acgagatttg tcgcggttag ctttgttttt
    76861 gtggattaga ccttttgatt cagccatatc aatagcttta acagcttctt tatataacgc
    76921 atctacgttg tcagcacctg aagctacagc atcttcaaat tttttgattg cagtacgcat
    76981 agcgcttgtt tgagatgaat ttttcacatt agcgttttcg cttgtacgaa cacgtttgat
    77041 tgcagattca atgtttggca ttagtttcac ctccgataac ttaagttctt acgcgtgtta
    77101 ccgcataatt caacattcat tattatacct aaaggcagcg tgctttgcaa tatgaacatg
    77161 acaagttttt ttccttaaca gtcttttatt aggatttttt ttcagtaaaa acggatagta
    77221 caagctgaaa aaaatcaaaa agacgctatt gtgggaggca atagcgtcaa accaaactag
    77281 atttttattt atctatttaa acaaagtttg aatgggaatg tttggtacta agttattata
    77341 taacaaagag aaccgtttgc aaagtttttt ttgaaaaggg atacgattcc ctgttgttct
    77401 ttgtttttct attaagaaac tgcagttatt ttataaccag tatcctttga tcagtaaagg
    77461 ctattctggt gtaccgatta ttttaatgta ttcatcgata ttttttatca acattttttt
    77521 tatgaccaac tggttccgac ggttccattt gccacttact tccagcacat atttatttag
    77581 gggcaaacgt aagatatatt ttgccaaata gcgatcttta agcaggccat tgatcacacg
    77641 gtcctcaagc tgcaagttga tcccagtcag catcattggc tgttcttgta aaacgtacgt
    77701 atcaattaaa agaccttcaa aagtttccac aagcgtcttc ctttcttttc aaagtaacct
    77761 gaaaacaggc actaattctt ccattttgat attcgttgaa gtggatgcga tcattctttc
    77821 ttttgtccac tgtaatctag tataacaaaa aagagcagaa gagccaaaaa gaaaaaagag
    77881 catcgaattc tataggaagt ctcattggca cggcctaaat tattacaaaa cattgattaa
    77941 aaaaagcccc tgcatcgcag gagcatcccc tatatcgttt taataggtca atcaaaaagc
    78001 agtatcaaac acattttgta tcaaatcagg aaataataga taagctaagc ccagaatcaa
    78061 aagtaccgct agaagaaacc agccgattgt tcctatgaaa tactttaatt tttcgaacat
    78121 tgtatcacct cgttgtcagt atatcacgga tcagtaaatt gggggtgtta agaatctcct
    78181 aaaatagaca aaatttgttc tattttccta aagcaaatac ttgtaagata cagtaagtga
    78241 taccagaagc aatgaccggt ccggcggcga ttcctcttaa gaagacaaca cctaaaatcg
    78301 tgccgaaaac aagtgcaaca gtgatttgtg gatcagaagc aatcaatcct acacccttgg
    78361 aagataagac agccactagc ccaccgcaaa aaacagctac ccagccaata ggggatttaa
    78421 aggcttctaa tagatcacgt agaccgattt ctcctgttgc gatagggatt agaatagccg
    78481 ctgtgatgat cgtcacccca atattgattc ctttgccttg aagccaaggg aaaaaggaac
    78541 gggaggctgg tatgagcttc ataatcaaaa caaaagctgc cgctatcatc agactttgat
    78601 ttttagctaa aattgctaca agtaaaataa ttcctaaaaa aagccaactt tccatgaaat
    78661 atattcctca ctttcttcga aacaatcata acatgttttt agaaagttac aaaagtagga
    78721 attcatcctt caagacctat tcataagctg tttttttcat aaaataaaca aaatcataaa
    78781 aaaacacttt gcttatttga cagaagacag ccgcgctttg tatagtggac aagacttaca
    78841 tttttttgaa gaatcagaaa gatcaggtaa aggtcttagt aaacgcaagc cattcagaat
    78901 aaccaatatt gtgcttcctt cgtgtcctac aactccaaga ggtagattta aaaattgcag
    78961 gaagttagaa gcaatcaaca agagaataac aagaatcgaa aaaataatat tttgtttgat
    79021 gatccgccgc atttttaaag atagccgatg actgtagaca aatttattta agtcgctttt
    79081 cattaagacg atgtctgcga tatccatagc ggcatctgtc ccttgcccca tagcgacacc
    79141 taaagaagcg gctgctaaag caggcgcatc attgactcca tcaccaacca tcgcatttac
    79201 ttggtaaagt tcattctctt ttttgactag ttgtgttttt tcttccggag tacagcttgc
    79261 atagtaatgt tcaatcccta cttgttcagc aatggccttt gctgtgccag aatggtcgcc
    79321 ggttatcata cttgtatgga tgttttggga tttaaagtag gaaattactt gttgggtatt
    79381 tgcttttgga atatctagca gacctaaaac agcaattaac tgctgatctt tagaaagata
    79441 aatcacggtt ttgccttgat tttccaaacg ttcgatcatt tccgcaatct ctttgctgat
    79501 tatcatcgtc tcaggatcat atgcgtgctt gccaactttc cattgcgcac ctaaataggt
    79561 agtttgtaat ccaaaaccag taatttcttc tattggtaag tattggattt cttcaggtat
    79621 tgtgcaatcg aaatattgca aaatcgcatg agcaagtgga tgcgtcgttt tttgttccat
    79681 agcaacaaga agttgttgtg ccaaatcctt ttcatcaaag aaaaagctgt cagttacaac
    79741 tggttttcct ttagtgagcg ttcctgtttt atcaaaggca atcgctttta attcagaaag
    79801 cttttctaaa tggataccgc ctttgattaa aatcccattt tttgcagaat ttgaaagagc
    79861 agctagagaa gctggtgtag cagatgcgac aagcgcacaa ggagaagcca caactaataa
    79921 taccattcct cgataaaagc tttcatccca actccaacct aggaaaaagt gggggagaag
    79981 gatcattaga ggaacagcaa gcaaaatcaa ttttacataa ttattttcga ttcgttcgat
    80041 aaatgaagct gtttgagttg gcgtattctg cgcttcttct actaattgga taatcttagc
    80101 aaagacagtt tcggaactcg tttttgttac tcgaatcgtg atgggatttc cttgattcag
    80161 cgttcctgca tacatctcat cgcctaaata tttttctaca ggcacagatt caccgcttaa
    80221 tgcagactca tcgatcgttg cctgtgtgct ttctaaaaag ccatctatcg gaacagctgc
    80281 tcctttagcg acaaatacca agttatccac ctttagttga gaaacatcta cttcttgcat
    80341 ttgtccattt tcttttaata attgggcttt ttgtggttga agattcatca aagcagtaat
    80401 ttctttttga cttttattag ttgtgtattc ctctaatgca ccgcttaaac aaaagatgaa
    80461 tgtcaacatt gctccttcaa agtaattacc gatcaaacag gcaccaatag cagctaaagc
    80521 catcaataaa tccacattca gtgtccgatc attccacaat tctttcaagc cttccgatgt
    80581 ttgtttatat ccaccgatga taatggcact gatataaaaa agtggggtga tggtaagaga
    80641 gaatcggtcg aagataaaac cgaagatcat aaataaaagg cagccgattg ttgctgcaaa
    80701 agcttttttc tgattagtca tcgttattag acctccttgt caaaacaagg atagcataat
    80761 aaaaatgtaa ttgataataa taacagctaa atgagaacga taatggttat catttggtga
    80821 ttaagcttga tgttgttttt attatttata atgattatta ttaaagaaaa taaaaaacca
    80881 gaacatttct caaataagag aagtgttctg gttttttcta cattgcaata aaccaataac
    80941 caatcaaaat gataccaagg ataatacgat accagccaaa agcggtaaag tcgtttttct
    81001 tcaaatagct tagtaagaat ttgatagcta agacggaaac cacaaaagat acgaatgttc
    81061 ctacaagaag aacaacagtt tcttccattt tgaatgaatt cccttcagct aaatatttga
    81121 cgatcttcaa gccgcttgcg ccaaacatga caggaatccc taagaaaaat gaaaactctg
    81181 tagcgacaaa acgcgaagca ccaatcaaga tagatcctag gatcgttgcg ccagaacggg
    81241 atgttccggg aacaagtgcc aagacttgga ataacccaac aagaagagct gcttggtacg
    81301 taaagtcatt cagagaagtc caacgaggtg ttttgttttt gttgcgtttt tcgacaataa
    81361 taaaggcaat accgtaaacg atcaaaacaa tggcaactgg taagaacttg tggaaatttg
    81421 cttctaacca atcatccaaa ggcaaaccaa tgatgatggc tggtatgcaa gcaacgatca
    81481 ctttaaacca aagtgtccac gtatcttttt tttctaccgt tgatttactt ggagaaaatg
    81541 ggtttaactt gtgaaaataa agaacgacga cagccaagat cgcccctaat tggataacga
    81601 cattgaacat cgacataaat tgtgaactgg catccagttt gatgaattca tctgctagga
    81661 tcaaatgacc agtactactg atgggcagcc attccgttat tccttcaata ataccgagaa
    81721 tcactgcttt gataatattt gcaaaaaaca taaattcctt ccttcccaat taagatacat
    81781 cttatagtat accgttattt tttgagaaac ccaatctgtt ttttaatatt aagaaaaact
    81841 tgagaaataa agcagataag tacacgaaga gaaaaaagaa gacaaagccc tcgttcagac
    81901 tttgcctttt atgattctct ggtaaaaatt aaaatatccc cattatagaa acgagtcgcg
    81961 actatgtgtt ttcccgttat cgatataaga cgtatcattg atgccgtgga tagaaaatcg
    82021 accgtttgca taagtgacct ttgttacgct gccatttaaa agcccagcac gaacaggctg
    82081 tttaggatcg atcagattaa gcaaaaaggc gatcgtcaaa ccatgagata cgactaaaac
    82141 atttccacca ccattttttt cgcagtgatg ggcgatatct tcaaatcctg tccatacacg
    82201 gtctcgcaat gtttcataag tttccgccca cccagcggta tctaagttgt atacagcatt
    82261 agcaatttgt tcaaaagaaa cttctgtggt aaacatttca tcatatgttt taaaattcaa
    82321 tacacgaggg atcacacccc acatttccat gtcatatcca ccttcaagag acccgaaaca
    82381 ccattctcta atcctttttt caataaaata aggaatttct tttcccttag aatgttctcc
    82441 tagaataata cgggcagttt cgattgcacg accactgtca ctagaataag caaatgaaaa
    82501 gtcgacattt tttaacccgc gacctaaata atgaatgcct tcttgtcctt gctttgtgag
    82561 gggtgtatca caccagcctt gtactcgttc aattgtattg aacatcgttt ttccgtgtcg
    82621 tacgatataa agtgtagttt ctgtcatttt attctcctcc taagtcgttt taacgattga
    82681 aaaaaggatt tgtccttttt tcctgttcaa tcgtcgttgc atcgccatgt cctggataga
    82741 ctgcaaattc atcaggtaat acaaacagct gggtccgaat actatgaagt aattgttcta
    82801 aattccctgt atacagatcg gttctaccga tacttcctct aaacagggcg tcgccagaaa
    82861 cgacaaaatc atcaaaaata aagctgacgc ttcctataga atgccctggg gtagggacga
    82921 cgcgaaaaga catgtttcct aaagtataag ttttcatttc aaattcatat tctgcaggcg
    82981 agacaataac atcagcaata tcatcatgtc taccgagtcc agaaagattc aaaatcggat
    83041 cacctagcca tttttgctct agtgggctga cataaactgg gatttgataa tacgcgcgta
    83101 aaggttccac tgcaccgata tgatcgtagt gagtatgggt aagcaaaatc gctaccggct
    83161 gttggtttgt ttttttgatt tcttgtttga ttcgttccgc atcttctcca gggtcaatga
    83221 tcaaaagtgc ttcttcgttg tagaccaaat aacagttttc ttcaatcatt cctgttttta
    83281 atctttcgat atgcatgtgc attcctcctt gatagccaaa acttctttca tccattagta
    83341 taacgcattc attgctagga aacaaaaaca ggtacttatt tctctttact tatctgaatt
    83401 atcagactat atgaaaagta tttggatatt ctaaagagaa ggaaagtaag ttttcatagc
    83461 attttaatat gtccttgtta cattagattc atccaaaaat ccaaattcta tatcctatat
    83521 ccctgcctaa tcagcagggt gtttttttat gtttggaaag agagctcttt ttgctaaact
    83581 aggttttttc aggtaatctt agagagaaag aggtggtgga aatgatcaaa cagtcaaaaa
    83641 tatctgtgcg gcacttagta gaatttattt tgcgacgtgg aagtatcgac aatcgtaaaa
    83701 aaagtaacca tactgcatta gaaggagcga gaatccaccg caagctccaa aaagatgcgg
    83761 gagaaaacta tgaaaaagaa gtctttttaa aaacaacagt tcaattagat gaatattacc
    83821 tgatcgttga aggccgtgca gacggtattt tcaaaagaga cggtatttat tatatagatg
    83881 aaatcaaaac ctccgaacca cgatttgaag atttagaacc agaacaagtg gaacttttct
    83941 ttcatcaagc aagggtgtat gcctatatct atagtcaaga acatgattta caagaaataa
    84001 atctgcaatt gacttacttc cagacggcag aagaagtgat cacgagaaag gttgaacatc
    84061 agacaagaga gcagttagaa acttttttta aaaagctgac tgaagattat aaagaatggc
    84121 ttgtttttca agaaaactgg cgcactgtac gcaatgcctc tttgatggct ttgaaattcc
    84181 cccatgatga gtataggaaa ggtcagcgtg aactagcggt agctgcttat aaaacgatcc
    84241 gtacgaaaca gaaattgttt gtagaagcac ctaccggaac aggaaaaaca atctctacgt
    84301 tattccccgc tttgaaagct gtaggggaag aagagggaga aaagatcttt tatctaacgg
    84361 ctaaaacaat aactagacaa gtagctgaag atgctatgac agcattaaaa gatacaggag
    84421 ctgaagtaaa aagtgtcact ttgacggcga aagacaagat ctgcttttta gatgagacga
    84481 cctgtaatcc agatcagtgc ccatatgcca atggttatta caatcggatt aatgaaggtt
    84541 tatgggatct tttgaatcat gagaatcaga tcactcgtga agtcatcgaa acttatgcaa
    84601 gaaagcatac actttgtcct ttcgaactat cattagatgt cagtatctgg tgtgacgtaa
    84661 tcattgggga ttacaattat ttatttgatc caactgttta tttaagacgt ttttttgaag
    84721 atgaaaaaaa cgaggactat ctgtttttga ttgacgaagc acataatttg gtgaatcgtt
    84781 cccgagagat gtattcggca gaactatctt atgaaaaaac gaaacgaagt aaggaagcta
    84841 taccaaagga attcaaaaaa cttcatcgcc gtttcaacaa actattaaaa gaatttgatt
    84901 cgatccgaga aatagcaaaa gaagatcatt gggattatca tcatcaaaaa gcaccggctg
    84961 aatctttagt aaaggcaggt tatcaattaa gcgaaaaaat taaagaatgg ctggcagaat
    85021 ttcctgagca cccatcacaa gaacaattgc ttccttatta ttttgatttg cttcattttt
    85081 tgaaggtcag tgaattttat gatgatcact acgaaacaac agtcgaaaaa acgtatcgcg
    85141 atctgatagt aaaagagttt tgtattgatc caagcttgtt tcttgagcag tcgttggata
    85201 aaggaaaaag cagtattctt ttttctgcta gtttttcacc actctcttat tatcaggaaa
    85261 cactgggggg acaaaaaagt ctggcttaca aactgccgag tcctttccca gaaggaaacc
    85321 agcaagtttt catcgcaaat tacctagaga cgacttatcg aaaaagggaa cacagtctgg
    85381 caaaattagt agagacgatt catgcttttg ctgatggaaa ggtcgggaat tatttcgttt
    85441 tctttccttc ttatcaatat ttagatcttg cggtggaagc attcagacag caatatcccg
    85501 acagcaatgt gctaatccaa gaaacggaca tgaatgagga agaacgcgaa cgatttttaa
    85561 caaaatttca aacaaatccc gctgaaacat tgattggatt ttgcgtactt ggcgggattt
    85621 tttcagaagg aatcgatttg agaggggacc gattgatcgg cagtatgatc gtaggtgtag
    85681 gtttgccgca gatgaatcat gagcaggaac tgatcaaatc atattatgat gagaaggaac
    85741 accttggatt tgcttacgct tatcagcttc ctggaatgaa caaagtcttg caagctggtg
    85801 gtcgagtgat tcgtggcatg gcggatcaag gaatcgttgt attggcagat caacgatttt
    85861 ctagtttttc ttatcgacgt ttattcccac aacattggca aacagcaaga gaagtacgaa
    85921 gtgttgggga attggaagaa ggaatacagc gtttttggtt atcaaaagaa gcagtaaatc
    85981 aaaaaaacga ggaatgacag acgtcagcct cgttttttga ttaacgatag ttagtgaatt
    86041 gcaactcgat tggtaagtca agtttacgta ataaagcaat cacagcttgt agatcatcac
    86101 ggttcttacc tgtcactcta atctgatctt cttggatttg tgcttttact ttcagttttt
    86161 catttttgat agctgtagtg attttcttcg cgttttcacg atcgattccg ttgaccaaat
    86221 cggcagtttg tcgagctttg ccacctagag cgtgttctga ttcggaaaaa tggatatttt
    86281 tgattggcac atttcttttg atcagcttac caaataatac atctttgatc tgttcgattt
    86341 tgaaatcatc atcgctcaat acaactagat tgctgttctc taatttgatt tctactgtag
    86401 aatccttgaa gtcaaagcga ttggacaatt cttttgttgt ttgctgaatc gcatttttta
    86461 cttcttctgt attgacttct gatacaatgt cgaagctagc atcttttgcc ataggaaccc
    86521 tcctgatata catataaata tttaccatac atctatctta tcataggatt agggcagatt
    86581 cttacctgtt tgctaaaatt cttctcattt gagttcgaag tattttattt taatagataa
    86641 actgttattc ttacatttgg aataccaaag taggggagag gtgcttgtga gtaaaattat
    86701 gactgcgtat cataaaaatg aaagattaaa gaaaatagtg gttattttga taaccggatt
    86761 gaccgctgcg gtcgctttaa attatttttt gattccagcc aatgtctttt ctgcagggat
    86821 gaatgggatc gctcaaatca tttcctcgct tttatatgaa tggtttcata tcaagataga
    86881 cacaggaaca tttatttttc ttttgaatat ccctgtgttt gtattagggt ttctcaaagt
    86941 aggaaaacga gcaacgatcc ttagttttgt gaatgttgta tgtgtatcgg tgatgacgat
    87001 gctgcttcca gtcggacaga tcactgataa tattttgatg aatgccctag taggcggtgt
    87061 tttattaggt cttggcgtag gattatcttt aaaaatgggc tttacaactg gtgggatgga
    87121 tatcatctct cttgtacttt cacaaacaac tggaaaaaca gtcggaaact acatgctgat
    87181 tctaaatggt atcattgtag tcatcgcagg cttcttcttt aactgggaaa gtgccttgta
    87241 tacgattatt tccatttatg caatgactca agtaattgat gccatccaca cgagtcatca
    87301 aaaagtaaca gcaatgatcg ttaccgtcaa gccagaagag gtaacagaag aactagcaaa
    87361 acggatggta cgtggaatga cattactgcc gtctgtcggt ggctattcaa aaaaacaagg
    87421 gaacatgatc atgatggtca tcacccgcta cgaaatgtat gatcttgatc agatcgttca
    87481 tgaaatcgac gacgatgcat ttatcaatat tttaccaact cattcagtat ttggccggtt
    87541 tgcaaatgaa aacgaacaaa aaatgtatcg aacaactggc gtattgccag aaataaaaaa
    87601 tcgttcacaa aaaaaatgag gaatcaggtt tattttagaa taaatttaat ctattacatc
    87661 taataagaac atttttataa atttaaacga gaatcttact tctaaattct catttacaag
    87721 cagctaaaaa aagagtatga taaataaaaa tcgtgttaag gagtgtcgta cgatgagcga
    87781 agcaaaccaa gaacggtctg gacaagaaat agaactaatc aaagaacgta ttcttgctgc
    87841 cttggaaatg gtgattgatc ctgaattagg aatcgacatc gtcaatttag gcttgattta
    87901 tgatatagaa ttcaatcctg aaaatggaga aacagtcatt aagatgactc taacaactat
    87961 gggctgtcca ttagcagata ttttaacaga atctatccat gacgcattaa aagaagtgcc
    88021 agaagtaacg aaagcagaag tcaaactagt ctggtatcca gcatggacga cagataagat
    88081 gagccgttat gcacggattg cgttggggat acgatagaaa tcttggctga ctagctatga
    88141 gaagcaaata ggaaaaacaa aaaagccttt tatcctttct agaagaaaag agataaaagg
    88201 tttctttgtt tataaaattt tgtctgctat attataagtt aattaaataa atgtgttcta
    88261 ttgataaagg acattcaaat ccctttcctt ttggaatcct tcttttttac atcagtttga
    88321 ttttcgtata gtattctttc tcatcttcac gataaatcgc agccccattt ttttgttgtg
    88381 ctttaagact gccaagattt tttttattta cagacaaaag tgcctcatca atgccgattt
    88441 tttttgcctc ttgtagtact aatgctaatc cttgtgtggc atatcctttt ttacgataat
    88501 taggggagat gccgtaacca atatggccag cgccgtttct taatgtttcg ttcagtttat
    88561 ggcgcaaatt aaaaattcct acatactcat gttcatcact ttctaaaata aagacggttg
    88621 cgggaacgta actctcagga agatcgattc ctaaagacgt tttttcgcat ttttttacat
    88681 aatctaaaaa ttcagcaaat gtatagccat aagcattgtt gataaatcca ctctcatttg
    88741 gtccaaagct agtttgtagc tgataagctt tctttaaatc tgcttcccat agtttgatca
    88801 gtttcatcgt attcacctct ttaagtaacc ttattcattt gttttctact atagcactat
    88861 tgttgtaaat agccatgcct atttttattt attgtgtcat atcgtattaa gaatcatcga
    88921 acaatacaaa tatgaattac aataaaaaaa ttatttgaag ttcgttcatt cgttacttat
    88981 gatctctaga agaaagaaaa cgtgaattac ttcagcgtct agaattccag aaggatagta
    89041 atcaacagaa gaaataatca atatccaaat gaaagaagat agctgaatcg agaaaaagag
    89101 gaaaaaagaa atgaagaaaa aaataaaata gttactaatc ccagagtcgt tcgtttaaca
    89161 ttgaaatcga tcatatggat aaaacagatt ttttcaccaa ccctcaatag atgatggagt
    89221 tgctcggatg aattatttgt gtagatggca taagggaggg cgtacagaaa tgaaaaagaa
    89281 caaaaatatg ttcttgacaa aaaacacatg taatcctaaa ctaaaagatg tgatgcggct
    89341 atggcggaat tggcagacgc gctagcttca ggcgctagtg agggtgacct cgtggaagtt
    89401 cgagtcttct tagccgcata atttgttttt ttataaagag aaggtacacc tggagcgatg
    89461 agaaagaaaa taacatatta tctaaaagaa tataggaaaa attttaaaca acggaaccag
    89521 attcaaataa atcaaaaaaa atttgtgtga aggtgggaca gtttaaaacc taatagattg
    89581 attcaaatag tagatttata gattctgata caagaaatac tggcaaacga tagttaagga
    89641 ataaagacta aacttaaact caaaaagagg tcatgcgaaa gaataaatcg catgacctct
    89701 tactatattt tgaatgtgtt taaacgttca aataatgaat cttagtacca accgtttgct
    89761 tcccagaatg ctttcgccgc ttcccaagaa ccataacgtg aagtaacata ttgttctgct
    89821 actctttctt ggtttgcagc agagtagtca ccatttaagt aagaagaatc taattggtaa
    89881 cggccgatgt aacgtccgtt cgttgctgtg taagaaccgc ttgattcttt ttgtgcgatc
    89941 cattcttttg cagagcttgt acttgctgga gtagcagcag tttctgttac agcaggagca
    90001 ggttgtgttt cagcaacagg cgctgcttgt gtttccgttt gaaccgtttc ttgtacaaca
    90061 ggttgttcag cttgaacagg ttcagcttgg actggtgctt cttgaacggc tgcttgaggt
    90121 tcagcagctg cttgtgcaga gccttctgtt gggattgtta attgttgtcc tgagta
//
LOCUS       DAFBVQ010000007        80101 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.007, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000007 DAFBVQ010000000
VERSION     DAFBVQ010000007.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 80101)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 80101)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..80101
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.007"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            373..3180
                     /locus_tag="LLC22_000571"
     CDS             373..3180
                     /locus_tag="LLC22_000571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5433871.1"
                     /translation="MYVKEKTAHLTKAEYDQGVTTQEIAEVLGIQRTNSSKDLNQLVR
                     EGKLIKTDGRPVRYIYQTLVTHVKPVTKHVVSYKETPVSEEKNTLQIDTKDIFAKIIG
                     ANGSMKNSVEQAKAAILYPPRGLNCLITGPTGSGKTYFAHAMYHFAKAHHVIDEETEL
                     IVFNCADYANNPELLMSHLFGYAKGAFTGADEEKMGIIDQADGGMLFLDEIHRLPPEG
                     QEMIFYFMDHGTYSRLGETTKSHEANVRIVGATTEDPGSSLLETFVRRIPINIKLPAF
                     EKRPANEKVDLVKIMIAHEANRTQRKISLTEDVAKALIGSVTYGNIGQLKSNIQLVCA
                     RGFLNHMQSPEISITIDDLTEGIRSGLIQLASNRSAMAELSKILEPKITVAPNDTIMK
                     IQSDSYELPYNLYDIIGDKAALLKSDGLDQEAINHFISTDINIHLKSFYKDHGFSFNA
                     DSKLAEFVDPKIIEVTNQIYVMVKRSLPYEFQQNFIYAMSLHISSFLKKINLGEERHT
                     NDNIREMAFDFPDEYAVAKEVRSYIETYFQVEIPESEDYYLTVLLVSLRANQASGRIG
                     VVVAAHGNSTASSMVQVVQQLLDAENVRAVDMPLDMDPKTALDRIERNVQEVDEGSGV
                     ILLVDMGSLASFNSQIQRDTGIPVRTVDMVTTSLVLETVRKVSVLGTDLDMLHESLKN
                     FRGYAEISSVESVQEAKPIHKKKAVLAICASGEGTAQRIKELIERAVNKRQETELEVL
                     ALSIVEVKEELPVIQKEYQIIATTGITDLNIQAPFIPLERFIDQNIEVILDQLLMESE
                     LEETEFISLDEESAKNTCVEFISDNFIFINGSKLIDPMWQFSTQISQTTGIGDEEYGF
                     KINLVMHTAGMIERIIRNEPLTVEENELTNTTNDPLYSQLAASVVLLEDQIKVKVPIE
                     EMYYLLRLVHNQLDKKEYTVP"
     gene            3371..3862
                     /locus_tag="LLC22_000572"
     CDS             3371..3862
                     /locus_tag="LLC22_000572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342244.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5433872.1"
                     /translation="MDIRLARIDDRLIHGQVATVWSKQTGVERIIVISDVVAQDKLRK
                     FLLKEAAPPGITANVITVQKMIQIYHSGLLSRAKVMLLFTNPQDVEAVVRCGVQLKSL
                     NIGGMSFTEGKSMITNFVSVNQQDIDSFRYLNSQEVELEIRKVPADRKILLMELLAKI
                     KKV"
     gene            3965..4954
                     /gene="manX"
                     /locus_tag="LLC22_000573"
     CDS             3965..4954
                     /gene="manX"
                     /locus_tag="LLC22_000573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIAB"
                     /protein_id="HBK5433873.1"
                     /translation="MVGIILASHGQFAEGILQSGSMIFGEQENVKAVILKPSEGPDDL
                     RAKLEEAVASFDNQDEVLFLVDLWGGTPFNQSNTLFEEHKDKWAIVSGLNLPMLIEAY
                     ASRFSMESAHEIAAHIIETAKDGVKVKPEELEPAEAPKAAVEDAQPKGALPEGTVVGD
                     GKIKYVLARVDSRLLHGQVATAWTKAVQPNRIIVVSDAVSKDDLRKRLIEQAAPPGVK
                     ANVIPISKMIEVAKDPRFGNTKALLLFENPEDVLTAVEGGVDIKELNVGSMAHSVGKV
                     VVSKVLSMGQEDVEAFEKLEQKGVKFDVRKVPNDSRDNMDDILKKAKAELAKA"
     gene            4987..5790
                     /locus_tag="LLC22_000574"
     CDS             4987..5790
                     /locus_tag="LLC22_000574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter subunit
                     IIC"
                     /protein_id="HBK5433874.1"
                     /translation="MSIISIILVVLVAFLAGMEGILDEFQFHQPLVACTLIGLVTGNL
                     EAGIVLGGTLQMIALGWANIGAAVAPDAALASVASAIILVLGGQGVKGVPSAIAIAVP
                     LAVAGLFLTMIVRTIAVPIVHLMDAAAEEGNIRKVEMWHIIAVCLQGVRIAVPAAALL
                     FIPAQTVQSFLESMPAWLTDGMAIGGGMVVAVGYALVINMMATKEVWPFFVIGFVVAA
                     ISQLTLIALGALGVALALIYLNLSKMGGSSNNGGGSNSGDPLGDILNDY"
     gene            5811..6725
                     /locus_tag="LLC22_000575"
     CDS             5811..6725
                     /locus_tag="LLC22_000575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose/fructose/sorbose transporter family
                     subunit IID"
                     /protein_id="HBK5433875.1"
                     /translation="MAEEKIKLSKKDRLAVAWRSTFIQGSWNYERMQNGGWAFSMIPA
                     IKKLYKTKEERSAALKRHLEFFNTHPYIASPILGVTLALEEERANGAPVDDVAIQGVK
                     VGMMGPLAGVGDPVFWFTVRPMLGALGASLAMGGNILGPIIFFLGWNIIRWAFMWYTQ
                     EFGYKAGSKITDDLSGGLLQDVTKGASILGMFVLAALVQRWVSIKFLPVVSTVKLDKG
                     AYIEWDKLPSGGEGIKSAFEQVNNGLALSPEKVTTLQDNLDQLIPGLAALGLTLLCMW
                     LLKKKVSPIVIILGLFVVGVVGHVIGLL"
     gene            6808..7182
                     /locus_tag="LLC22_000576"
     CDS             6808..7182
                     /locus_tag="LLC22_000576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF956 family protein"
                     /protein_id="HBK5433876.1"
                     /translation="MVQSINTKVDLVIDATSFTGLTDYGQIMIGDNGFEFYHARDRRK
                     YIQIPWEEVDYVLASVMLKGKWIPRYAIQTKKNGTYTFSSKEPKKVLRAIREYVDEDR
                     MVQSLSFFDVVKRGIRSMFKRK"
     gene            7321..7566
                     /locus_tag="LLC22_000577"
     CDS             7321..7566
                     /locus_tag="LLC22_000577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5433877.1"
                     /translation="MSWLWTLIVGAVIGAIAGAITSKGNSMGCVTNIIAGLVGSSIGQ
                     AIFGEWGPKAAGMALIPSILGAVILVAVVSFFFGKRS"
     gene            7738..8802
                     /locus_tag="LLC22_000578"
     CDS             7738..8802
                     /locus_tag="LLC22_000578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK5433878.1"
                     /translation="MMLRVEKLRKKMQEENLDSFLVTSPYNLRYLTNFTGTTGLAVIT
                     LEKAFFITDFRYTEQAAAQAQGFEIIKNVGPIFDEVANLVRKEELHSLAFEETTVSFL
                     EYSVLEEIIDAELVPVSQMIEELREVKDEEEIAIIEKACHIADMAYDHILKMIQPGMT
                     EIEVANQLDFYMRSLGASGVSFDTIVASGLRSAMPHGVASKKIIEQGDLITLDFGCYY
                     EGYVSDMTRTFAIGDPGEKLKEIYQIVLDAQLAVIDAAKPGMTGVQLDAVARDYISKH
                     GYGEAFGHSTGHGIGLEIHEGPNVSSRAEKQFVPGNVITDEPGIYLPGIGGVRIEDDL
                     LITEDGNRVLTRSPKELIIL"
     gene            9048..9473
                     /locus_tag="LLC22_000579"
     CDS             9048..9473
                     /locus_tag="LLC22_000579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5433879.1"
                     /translation="MADEKNLILNANQDLGEIVIAPEVIEVIIGIAASKVEGVYGMRG
                     TFASNVTELLGRAAHGKGVYLANEEDGLKVDLYCYLEYGVSVPKVAMEMQERVSQQVL
                     FMTDIDLSEVNIHVVAVVPEKLEQPTIEELFEDEEEENE"
     gene            9466..9915
                     /gene="nusB"
                     /locus_tag="LLC22_000580"
     CDS             9466..9915
                     /gene="nusB"
                     /locus_tag="LLC22_000580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751503.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription antitermination factor NusB"
                     /protein_id="HBK5433880.1"
                     /translation="MNKELSRHEIREMALQALFPLDFNADLTKEDAIFNAIELDHRDM
                     INEDESEFVPVYLDTLVGGVCAKKDELDKVIEKHLKNNWHINRISKMDLVILRIAIFE
                     MTYVTDVPAAVALNEAIELAKTFSDDRSRKFVNGVLSNVLKELEAGA"
     gene            10012..10866
                     /locus_tag="LLC22_000581"
     CDS             10012..10866
                     /locus_tag="LLC22_000581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional methylenetetrahydrofolate
                     dehydrogenase/methenyltetrahydrofolate cyclohydrolase"
                     /protein_id="HBK5433881.1"
                     /translation="MAELINGKELAEKMQAEIAEKIQKLKDNGIHPGLVVLLVGENPA
                     SQIYVRNKERVAKEIGIHSLVERYPETISEDELLAEIEKYNQDPSFHGILVQLPLPKH
                     IDEEKILLAIRPEKDVDGFHPMNLGRLLAGKPDKIPCTPYGIMKMFEAYSIDPAGKRA
                     VVIGRSNIVGKPMAQLLLMADATVTVAHSKTENLAELAQEADILVVAIGRGHFVTKEF
                     VKPGAVVIDVGMNRDANGKLIGDVKFDEVEPIAGWITPVPKGVGPMTITMLMYQTVKS
                     AEAFGAGE"
     gene            10867..12204
                     /locus_tag="LLC22_000582"
     CDS             10867..12204
                     /locus_tag="LLC22_000582"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII large subunit"
                     /protein_id="HBK5433882.1"
                     /translation="MAQEYLTVTTLTKYLKRKFDADPYLERVYLTGEISNFRLRANAH
                     QYFSLKDDHAKISAIMFKGAFQKLRFQPKEGMKVLVVGRISLYEAGGSYQIYVEHMEP
                     DGIGALYQELEERKEKLMKEGLFQGPKKMLPRFPKRIAVLTSPSGAVIRDIITTVKRR
                     YPIVQLVLFPTVVQGNQAADNVVRNIQRVEEMGNFDTMIIGRGGGSIEDLWPFNEERV
                     ARAIYQANTPVISSVGHETDTTIADLVADVRAATPTAAAELAVPVLSEELMRIQERQA
                     RLQQAFVRQIQRKQERFERARRSYVFRQPERLYEGQTIKLDQLKQRLYQATQQIYHAK
                     EKQTIALSHQLEQVAPLYRVKAARQETAYLEKRLEEKIQQYMKQQQQRFAQAVQSLDL
                     LSPLKIMGRGYSYTTLNDQVVKSVTEIHQGDLLTIHYQDGIVKGQVQEIDKGE"
     gene            12209..12433
                     /locus_tag="LLC22_000583"
     CDS             12209..12433
                     /locus_tag="LLC22_000583"
                     /EC_number="3.1.11.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease VII small subunit"
                     /protein_id="HBK5433883.1"
                     /translation="MENPTFEESLQELEKIVMQLEQGDVPLESALDSFKRGMELSKHC
                     QDTLAKAEETLTKMMTESNEEVDFDGNEES"
     gene            12435..13325
                     /locus_tag="LLC22_000584"
     CDS             12435..13325
                     /locus_tag="LLC22_000584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBK5433884.1"
                     /translation="MRLTDFSAIHLPAVEKEILSFLDEHTTDRGLYDAMSYSVKAGGK
                     RIRPLLLLTAVASFDEPIDVPVYQVAAALEMVHTYSLIHDDLPAMDNDDLRRGKPTNH
                     KVFGEALAILAGDGLLTGAFQLISMAHLGNSPKLLLLQQLAVCAGSQGMVAGQAADIE
                     GESKKLSLEELAFIHERKTGHLIRYALLAGGILAKQPEEILLLLQRLAEHLGLAFQIR
                     DDLLDVIGTTKTLGKTAGKDERMEKNTYPRLLGLEKTREALEIELLSANKIIDKLEED
                     VFSFDGGLMRQMIKQFDVEK"
     gene            13334..14152
                     /locus_tag="LLC22_000585"
     CDS             13334..14152
                     /locus_tag="LLC22_000585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlyA family RNA methyltransferase"
                     /protein_id="HBK5433885.1"
                     /translation="MEKERVDVLAVKQGLFETREQAKRSVMAGLIYNEKNERFDKPGE
                     KIPVSSELRVKGKKLPYVSRGGLKLEKALKAFDLSVEGKTLLDIGASTGGFTDAALQN
                     GAKMSYALDVGYNQLAWKIRQDPRVVVMERVNFRYAKPEDFTLGIPEVAVIDVSFISL
                     KLMLPPLHAILKEEGEVIALIKPQFEAGREAVGKNGIVRDPQTHQKVLEDILSFAAQG
                     GYDVLELSYSPITGGEGNIEFLAHLRKVPESGTINSAINMAEVVSNAHEQFDHK"
     gene            14259..14708
                     /locus_tag="LLC22_000586"
     CDS             14259..14708
                     /locus_tag="LLC22_000586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine repressor"
                     /protein_id="HBK5433886.1"
                     /translation="MRKKDRHRLITRLLSEQDIRKQEEFVEILKSKGISVTQATISRD
                     IKELKLIKVPASDGGYRYSIPAETNEDVNTKLEKLLKDAFVAVDQMEKFVILKTLPGN
                     ASAAANLIDKRYKKELFSIINDDDNVLMITRTEDQAVLLKKDFLHYL"
     gene            14726..16408
                     /gene="recN"
                     /locus_tag="LLC22_000587"
     CDS             14726..16408
                     /gene="recN"
                     /locus_tag="LLC22_000587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecN"
                     /protein_id="HBK5433887.1"
                     /translation="MLQEISITNFAIIPELRLSFHEGMTALTGETGAGKSIIIDALGL
                     LAGGRGSSDYIRQGAEKCVLEGLFELPKQEGFSELMVELGIETDEDNLIVRRDMSLTG
                     KNVCRVNGHIITLANLRRIGSYLVDIQGQNEHQELLQPESHLALLDRFGDVAFQQKKK
                     SYQQEYISYRELEKRVRKVQQNEKSYVQRIDMLHFQQEEIAAADLQVGEEEKLKEERE
                     KLSNYQKIADGLAAGYGALTNNEQNSVDGVGLAVSELQGIAHLDVEYEAIYENIQSAY
                     YLLQDAIGDMSRQIDLLELDESRLEEVTQRLELIRQLKRKYGESIESILAYYDEITEE
                     LASSDFSEGQLDKMKEELEQKELLLQQQAADLHEARKKIAKELEKSILHELKSLYMEN
                     TEFEVRFLKEENRQLNHDGFDQIEFYITTNPGEPLKPLVKVASGGELSRMLLALKTIF
                     SSEQGVTSIIFDEVDTGVSGRVAQAIADKISQISKYSQVLCITHLPQVAAVADYQYYI
                     VKAVIDGRTQTSVSELKTKEREEEIARMLAGSEITKLTLEHAKELLKLAKRT"
     gene            complement(16463..16579)
                     /locus_tag="LLC22_000588"
     CDS             complement(16463..16579)
                     /locus_tag="LLC22_000588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4044 domain-containing protein"
                     /protein_id="HBK5433888.1"
                     /translation="MREKKQTSTFAKVTKFVIWTMLILTIGSVVLTAVMSVM"
     gene            complement(16652..17608)
                     /locus_tag="LLC22_000589"
     CDS             complement(16652..17608)
                     /locus_tag="LLC22_000589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK5433889.1"
                     /translation="MIKYFTLDNEKLRNTGKETDQTIWYCVERPNQEEIHQLTHQFEI
                     PSDYITSILDDAENSRTEEFNQSKLTKPALLLLQYPFAKTSPSGYFQVDTYPLSIILT
                     PKKKLITITNHEPLFLKKVFSQTFPKSDISPNLNIFFQFIWQVTLSYNSYLATLQSQC
                     DTLEAKLQVSTENKQLYQIMDIQKSLVYFREATSANLDALKELAQNKLFQENHALKNH
                     LRDVLVETEQAMTTSRIQLKLVEQMNQTFSAIVSNNLNNIMKILTSLTIILTIPTIVG
                     SIYGMNIKLPIAERDDAFIWLVLLTLFICIVTTYYLKKGKFL"
     gene            17779..18147
                     /locus_tag="LLC22_000590"
     CDS             17779..18147
                     /locus_tag="LLC22_000590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3397 domain-containing protein"
                     /protein_id="HBK5433890.1"
                     /translation="MGTFTPLILFWYIYPVIVLFGCQFLVKLFSLNRRFKIKAPDLAI
                     PFLWGGMHALSRNTGTISILPFFFISVLLMGICIAVFQAYYYEEIIYPRYFKMTWRLV
                     FLLTIVLYAVLIIVNILSYL"
     gene            18318..18749
                     /gene="mraZ"
                     /locus_tag="LLC22_000591"
     CDS             18318..18749
                     /gene="mraZ"
                     /locus_tag="LLC22_000591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005881057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="division/cell wall cluster transcriptional
                     repressor MraZ"
                     /protein_id="HBK5433891.1"
                     /translation="MLMGEFQHNIDAKGRLIVPSKLREELGEKFVLTRGLDGCLFGYP
                     MSEWENLEAKLNEMPLAKKDARTFVRFFYSAATECELDKQGRINIPSTLRNYAALTKG
                     CVVIGVSNRIEIWDETRWQDFSAAAEENFDEIAESMIDFGL"
     gene            18770..19729
                     /gene="rsmH"
                     /locus_tag="LLC22_000592"
     CDS             18770..19729
                     /gene="rsmH"
                     /locus_tag="LLC22_000592"
                     /EC_number="2.1.1.199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(1402)-N(4))-methyltransferase
                     RsmH"
                     /protein_id="HBK5433892.1"
                     /translation="MTETFQHYTVMLKETVDGLNIKPDGVYVDCTLGGAGHSEYLLSQ
                     LSSKGHLYAFDQDQKAIDHAKLRLASYVEQGMVTFIKANFRELEERLSEHVDKVDGIL
                     YDLGVSSPQLDEAERGFSYHQDAPLDMRMDQSAPLSAYHVINEYSYHELVKIFFRYGE
                     EKFSKQIAREIERVRKTKPIQTTGELVEIIKQVIPAPARRKGGHPAKRIFQAVRIAVN
                     DELGAEEASLEQAIRLLKVNGRISVITFHSLEDRIVKSMFKEYSTVQDLPPGLPVIPD
                     EFQPELKVITRKPILPSEEELTENNRSRSAKLRIAEKIRMKEE"
     gene            19734..20135
                     /gene="ftsL"
                     /locus_tag="LLC22_000593"
     CDS             19734..20135
                     /gene="ftsL"
                     /locus_tag="LLC22_000593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsL"
                     /protein_id="HBK5433893.1"
                     /translation="MAELKKMQDYEYDLPELVDQPEQQMPDSSSNQEIILPQSPAKRL
                     KQISALEKIAVASVAIAIVALCVLTVMLRTNISGAEKEITSIQTEINDKKQEKTSLEQ
                     EKNELSRTERIKQIAEEKGLSINDDNLRKVK"
     gene            20136..22328
                     /locus_tag="LLC22_000594"
     CDS             20136..22328
                     /locus_tag="LLC22_000594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326487.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBK5433894.1"
                     /translation="MSLKNKIRRFMEKKNLNPINNRKKVGIILFATSIGLFFLFAVRF
                     SYIVIGGHVAGTSLAEKTKQLYQGSEVVKAKRGTIYDRNGVALAEDASSYSIKAILSK
                     TYTSGDKKLYVEEKNFDKIAEILHKNLSIDKKDALNILEDGAKKELYQVEFGSYGKNI
                     SQETKQNIEADMKKEGVAGLYFVDHQARMYPNGVFSSHFIGYAVPDKDENGLVGKLGL
                     ESAYNDILSGKDGKIIYQKDNFQNPLPGTVAEEEKAVDGQDIYTTLDSRLQSYLETLM
                     DQVNEEYQPEELTAVLMKAKTGEILAMGQRPTFNPETMEGLTGKDAIWRNFLVQDSYE
                     PGSTMKVFTTAAAIEEGEFNENETFQSGKIQVEDATINDHDFGEKGVLTMRQALSWSS
                     NVGMVILEQRLGGRWYNYLQKLGFGQSTHSGLDDEVNGALPTLNIVDRAMSAYGQAVG
                     VTNFQMMKAFTSIANNGTMIQPRYISKVVDPQTGEERTTQTEVLGQPFSKETTEKVRE
                     YMRDVVESENYGSAYGVYSVPGYNVSAKTGTAQIASDTGGYQTGDTAYLYSIVEMVPS
                     EDPDYVLYLTMKHPKTYDRMALAKIANPLMKRAMDFKETEEDSDTETKTEKVSVADYR
                     NLEADVAAADAQKSGLQPVVIGNGKKVQKQSTANGDQLISGEKLILYTGGDKLMPDVT
                     GWSKADIMKLGKILGIEVSFDGDGYCVKQELAPYEKITEDKLSFTLEE"
     gene            22354..23316
                     /locus_tag="LLC22_000595"
     CDS             22354..23316
                     /locus_tag="LLC22_000595"
                     /EC_number="2.7.8.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-N-acetylmuramoyl-pentapeptide-
                     transferase"
                     /protein_id="HBK5433895.1"
                     /translation="MEWTQALIPIVSSCAMTIAAMPLFIGYFQMKKQGQAIREEGPKW
                     HNSKAGTPTMGGLVFLIGSILTGIWVGAWQKQLTPTLFILLFVLALYGVIGFLDDFIK
                     IFKKRNMGLNSKQKLIGQILGGIIFYLVYRSEGYPGVLNFFGLDLPLGIIYGIFALFW
                     LVGFSNAVNLTDGIDGLVAGLGSISFAAYGLIAWHQHQYDVLIICLSVLGGLLGFFVY
                     NRKPAKIFMGDVGSLALGGLLAAISIMLNQEWTLLLIGLIYVMETASVMLQVTSFKLT
                     GKRIFKMSPIHHHFEMCGWSEWKIDTVFWLISIVTSLITLWIVW"
     gene            23330..24691
                     /locus_tag="LLC22_000596"
     CDS             23330..24691
                     /locus_tag="LLC22_000596"
                     /EC_number="6.3.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanine--D-glutamate
                     ligase"
                     /protein_id="HBK5433896.1"
                     /translation="MKKISTYENKKVLVLGLAKSGVSAAKLLHELGALVTVNDGKPFD
                     ENPEAQELLSLGIKVITGSHPIELLDEEFSLMVKNPGIPYSHPLVAKAQEMGIPVITE
                     VELAYEVAECPIIGITGTNGKTTTTTMTGLLLNAGADQGIARLAGNIGYPASGVAQEA
                     KSEDKIVMELSSFQLMGITDFRPHIAVITNIYEAHIDYHGTRKEYVKAKWNLQKNMTE
                     KDYLILNWNQSELQELAQRTKARVLPFSTKEVLEDGVYADDYSIYYKKEKIMEISELG
                     VPGKHNVENALAAISVAKLYGISNEAIRETLHFFHGVPHRTQYVGEIQGRKFYNDSKA
                     TNILATKMALSGFETSKVVLLAGGLDRGNTFDELIPSLKGIKAMVVFGQTKEKLMDAG
                     KKAGIETIVTADSVEQAVPLALENSTDGDVVLLSPANASWDQYPNFETRGNRFMEAVN
                     RLK"
     gene            24717..25805
                     /gene="murG"
                     /locus_tag="LLC22_000597"
     CDS             24717..25805
                     /gene="murG"
                     /locus_tag="LLC22_000597"
                     /EC_number="2.4.1.227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyldiphospho-muramoylpentapeptide
                     beta-N-acetylglucosaminyltransferase"
                     /protein_id="HBK5433897.1"
                     /translation="MKILVTGGGTGGHIYPALAFVNYVKTQEPNAEFMYVGAKRGLEN
                     KIVPDTGMPFHTLEIQGFKRKISMHNIKTVRLFLKSIRQAKKILSDFQPDIVIGTGGY
                     VSGAVVYAAAKMGIPTVIHEQNSVPGVTNKFLSRYVDRIALSFKDAASFFPENKAVLV
                     GNPRAQEVADTKKSDILKTFDLDPEKKTVLIFGGSQGALKINQAVSVFLSEYIPSSYQ
                     VLYASGDRYYEEILNKINPEIQNISVQPYIKNMAEVMASSDLLVGRAGATSIAEFTAL
                     GLPAVLVPSPYVTNDHQTKNAMSLVHAGAAKMIADNELTGESLSQTVNEIMGDEELQK
                     QMCRASKEQGIPDASKRLYDLVKQIIKK"
     gene            25820..27040
                     /locus_tag="LLC22_000598"
     CDS             25820..27040
                     /locus_tag="LLC22_000598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsQ/DivIB"
                     /protein_id="HBK5433898.1"
                     /translation="MSKKKEPKKLSHPSSDENNLTPWQKANRKYLAEQEMKNQEPKKE
                     DITLDTPLSDSEEEKTVQEEQQEESQSEKKIEFFEEIKQKKNGGPYNGSFLNRLPNLK
                     SQRHKVLFRRLALIITVLGIPLIFLIYYVSPYSKLQAVAVSGNKTVNSQEIISDTKLS
                     LGENVWGQYFHRSTYIDRLKKAQPRIETANIHFKGMNEFDLDVTEYKEIALIAKNNQY
                     YPVIENGTVLDEKVANPTKNLPILEEFKDSAKIKELTKQYNQLSSELQKAISEIKYTP
                     RASNKNLIQLNMNDGNQVIVNINNLANQMKYYSQVAKDMDEKGVIDMEVGIFSHPYGS
                     TQETEESGQSEETTESEENADQTNESSEEAETQKAQTPGSSSTNGSSDSNDSSETSQI
                     EDNPSTTPSSLNEN"
     gene            27196..28521
                     /gene="ftsA"
                     /locus_tag="LLC22_000599"
     CDS             27196..28521
                     /gene="ftsA"
                     /locus_tag="LLC22_000599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsA"
                     /protein_id="HBK5433899.1"
                     /translation="MAKTGMYVGLDIGTTSVKVVVAEYIDSQMNIIGVGNAKSEGINR
                     GIIVDIDKTVQAIQRAVRQAEEKAGIQIKGVSVGLPANMLEVENCQGMIAVNGDSKEI
                     TDEDVRNVASAALVRSIPPERQIVSILPQDFTVDGFEGIKDPRGMIGVRLEMYGLLFT
                     GPKTIIHNIRKCVENAGLIVNEMVITPLALTESILSDGEKDFGTIVIDMGGGQTTTAV
                     MHDKQLKFTNLDQEGGEFVTKDISIVLNTSFNNAEALKINYGDAYPERTSPDEEFPVD
                     VIGQSEPVKVDERYLSEIISARMEQIFNKAKDALDQIEALELPGGVVLTGGAASLPGV
                     VDLAQEIFGVNVKLYVPNHMGLRNPVFTNVISIVDYSANLSEVYQLAKIAVTGETSAA
                     RQMVVEQETTNTYESYEAPEETIYDEPEPKESGENVKNKIKGFFTNIFD"
     gene            28544..29785
                     /gene="ftsZ"
                     /locus_tag="LLC22_000600"
     CDS             28544..29785
                     /gene="ftsZ"
                     /locus_tag="LLC22_000600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsZ"
                     /protein_id="HBK5433900.1"
                     /translation="MEFSIDNNINDGAVIKVIGVGGGGGNAVNRMIEENVKGVEFITA
                     NTDVQALKNSKAETVIQLGPKYTRGLGAGSQPEVGQKAAEESEQSLREALDGADMIFI
                     TAGMGGGTGTGAAPIVAGIAKELGALTVGVVTRPFTFEGPKRGRFAAEGIARLKENVD
                     TLLIISNNRLLEVVDKKTPMLEAFREADNVLRQGVQGISDLITAPGYVNLDFADVKTV
                     MENQGTALMGIGVASGEDRVVEATKKAISSPLLETSIDGAEQVLLNITGGLDMTLFEA
                     QDASDIVANAATGDVNIILGTSINEEMGDEIRVTVIATGIDESKKERKSSRPARQAQM
                     QSPAQKTVLDMDQAKPTSSEEENSFGDWDIRREQNVRPRVDDSNFDNIEKKEFDTFNR
                     EETKSHGDDELNTPPFFRRKK"
     gene            29802..30479
                     /locus_tag="LLC22_000601"
     CDS             29802..30479
                     /locus_tag="LLC22_000601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggS family pyridoxal phosphate-dependent
                     enzyme"
                     /protein_id="HBK5433901.1"
                     /translation="MIADNLQKIKQEIQDSCALVHRDPKEVTLVAVTKSVESAQAEEL
                     VRAGVMNCAENRVDKLLEKKQDLFDFPEIKWHLIGNLQRRKVKLIVNEIDYFHALDSL
                     RLAEEIQKRLEKELSCFIEVNVSGEESKHGISPDELLPFVESLAACTKIKVVGLMTMA
                     PKEASDEQIHKVFGTLKELRDLVQAKGYAHAPCSELSMGMSQDFQIAIEEGATFIRVG
                     TALFKDE"
     gene            30493..31092
                     /locus_tag="LLC22_000602"
     CDS             30493..31092
                     /locus_tag="LLC22_000602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326044.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein SepF"
                     /protein_id="HBK5433902.1"
                     /translation="MPLLNRGAIANFFGLADEEEYEYQDYPETTKKAVQPTKKNTTQN
                     QSTHSVSAANTHEKQKTATSRPVTHESIQPAEKKKVIELHQSPTKTVAKERTASRTST
                     QPKANLAGKITVMEPRAYSEAMAIAKRIIAGEATLVNFHLVEEKQARRIVDFLTGTVY
                     ALDGDIKRVGDEIFLCTPTGMEIDSSTAQSFADANLFDL"
     gene            31107..31394
                     /locus_tag="LLC22_000603"
     CDS             31107..31394
                     /locus_tag="LLC22_000603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YggT family protein"
                     /protein_id="HBK5433903.1"
                     /translation="MYTIALLLHLLQRAAYFYSIILMVYALLSWFPGGYQSGLGRLLA
                     KICEPYISLFDRLPLRIGPLDFTILGAILILNLAVQGLAQIVIWITVHLVY"
     gene            31443..32225
                     /locus_tag="LLC22_000604"
     CDS             31443..32225
                     /locus_tag="LLC22_000604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
                     /protein_id="HBK5433904.1"
                     /translation="MDANVYQHFRADERTFIDSVGDWIEQVQGQYAPYLTEFLDPRQS
                     YILETLIRQSSDLRFMFYGGYEQAERKRCLIFPDYYEPVEEDFETALYEIHYPSKFAS
                     LSHGKILGTLVGTGIKRSYFGDIISDGDRWQVFIANEVDHFVAAQVTKIGKVAVRLEP
                     IKYTEMIMPKDSWTQERGTVSSMRLDSVISEIYNISRQRSKQLIEAGKVKVNWTENTR
                     PDFVLELLDIISVRGYGRVQIQELEGKTKKEKYRVLFGVLRK"
     gene            32246..32953
                     /locus_tag="LLC22_000605"
     CDS             32246..32953
                     /locus_tag="LLC22_000605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DivIVA domain-containing protein"
                     /protein_id="HBK5433905.1"
                     /translation="MALTPLDIQNKTFPTKMRGYNQDEVDDFLDLVVRDYEELTQRNR
                     ELEKAVKHSEEKLEYFNELKDALNQSIIVAQDTADKVKTSASKESEVIVTSAQNKADE
                     LVANAEKRAHQLTTDAEEKARKILTDATEKARQLATETEDLKKKTRVFHQRISLMLES
                     QLEQVKSPEWDEILQPFSSYVTDSHEVIKEVLAKQLDNENDTDVNSDTGVIEAPMTAF
                     DTQAIDISIVPGENENE"
     gene            33215..36013
                     /gene="ileS"
                     /locus_tag="LLC22_000606"
     CDS             33215..36013
                     /gene="ileS"
                     /locus_tag="LLC22_000606"
                     /EC_number="6.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoleucine--tRNA ligase"
                     /protein_id="HBK5433906.1"
                     /translation="MKMKETLQLGKTKFPMRGNLPNREGEWQKEWEENRIYQKRQELN
                     EGKPSFVLHDGPPYANGNIHLGHSLNKISKDIIIRSKSMSGYRAPYVPGWDTHGLPIE
                     QVLANKGVKRKEMSMAEYLEKCREYALSQVDKQRADFKRLGVAGDWEHPYVTLDPSYE
                     AAQVRVFGKMAEKGYIYKGLKPIYWSPSSESSLAEAEIEYKDVKSPSIFVAFNVKDGK
                     DILDEDTAFVIWTTTPWTLPANQGIAVNPKFTYVLVEADGRKFVVAKDLLETVQSEIG
                     WENVTVLKEFAGQEMEYMTASHPFYERESLVILGDHVTLDAGTGLVHTAPGHGEDDYI
                     AGSKYKLSVVSPVDSKGLFTEEAPGFEGIFYDKANPMITDLLKEKGALLKLDFFTHSY
                     PHDWRTKKPVIYRATPQWFASIDKFRQNILDEVEKVEWVIPWGKTRLYNMIRDRGDWV
                     ISRQRAWGVPLPIFYAENGEAIITPETIEHVAKLFAEHGSIIWFEKEAKELLPEGFTH
                     PGSPNGEFTKEKDIMDVWFDSGSSHEAVLRQRPELSFPADMYLEGSDQYRGWFNSSIT
                     TSVAINGVAPYKSVISQGFALDGEGRKMSKSLGNIIAPEKVIKQFGADILRLWVSSVD
                     YEADVRVSMDILSQVAEVYRKIRNTMRFLLANTEDFDPKKDTVSYNDLRSVDKYMTVR
                     LNQVIKEIREEGYDKYNFMHIYRTVMNFLTVDLSSFYLDFAKDVVYIEAEDDYQRRCM
                     QTVFYQTAVALTKLLTPIIPHTAEEIWSFLKEEEEYVQLSEFPGYEEFANQEELMDTW
                     TAFMDFRDNVLKALEEARNSKLIGKSLEAKLTVYPKQQVREMLKALDADIAQLLIVSP
                     DYFEVMAADEQVPDNAMVFDDVAITVEKADGETCDRCRQVRKDVGVDEKLPHLCGRCA
                     KIVEDFYPEAVAEGFEEK"
     gene            complement(36062..37588)
                     /locus_tag="LLC22_000607"
     CDS             complement(36062..37588)
                     /locus_tag="LLC22_000607"
                     /EC_number="1.1.1.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate dehydrogenase"
                     /protein_id="HBK5433907.1"
                     /translation="MSNEKNVLFTIFGGTGDLAQRKLYPSLFRLYRKGNLGEHFAVIG
                     TARRPWSDEHYREVVKETIRALNPSDEEATTFASHFYYQSHDVNDSTHYQTLKELSDR
                     LDGHYQLNGNRVYYLAMAPQFFGTIVSHLKSQNIMTKNGFNRLIIEKPFGSDYQSAFE
                     LNQQIREVFPEQDIFRIDHYLGKEMIQNISAIRFANNIFEAQWNNRYIDNIQITFGEN
                     LGVEDRGGYYDHSGALKDMVQNHILQVVALLAMEPPVAFSEKEIRTEKIKALKAIRIY
                     NEEEVLENFVRGQYAQGELDGVQFKGYREEDKVDAQSETETFVAGKFTIDNFRWSGVP
                     FYVRTGKRLTEKGTRINIVFKQVPVNVFKTSVDEPCDDTTLPPNVLTIYIQPTEGFSL
                     SLNGKEVGQGFETEPIKLEFRNSAEMVENSPEAYEKLLLDALNGDGTNFSHWEEVAQS
                     WHIVDVIRKAWDQTQPDFPNYKAGSMGPKAAFELLEKDGFEWIWQPDNWYRERGKLND
                     "
     gene            complement(37603..38250)
                     /locus_tag="LLC22_000608"
     CDS             complement(37603..38250)
                     /locus_tag="LLC22_000608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent transcriptional regulator"
                     /protein_id="HBK5433908.1"
                     /translation="MTPNREDYLKIILELGGDTTKVNNKQIVSSLDVSAASVSEMISK
                     LVKEELVEHSPYQGVQLTASGLQKASSLIRKHRLWEVFLVEHLDYSWNEVHDDAEVLE
                     HVTSEHLADHLENYLNHPEHCPHGGSIPKKEEVVHEERRQTLESYPVGTKVRIARVLD
                     EKELLDYLVTIDLNINEEYEIVDIAAYEGPITIQNDRKKIPVSFKAASTIFVDKI"
     gene            complement(38434..38763)
                     /locus_tag="LLC22_000609"
     CDS             complement(38434..38763)
                     /locus_tag="LLC22_000609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4828 domain-containing protein"
                     /protein_id="HBK5433909.1"
                     /translation="MIYFLGSLITVLSSFIYLKKKKQAEKSEGLSKYQGTWFFSDSQQ
                     KQQLQITSDYTFLINGQSLGTSVVEIDEYRLVVRDQYGFYLIFSYPEQTLYDESADTS
                     YKLLSEK"
     gene            38940..39668
                     /gene="sfsA"
                     /locus_tag="LLC22_000610"
     CDS             38940..39668
                     /gene="sfsA"
                     /locus_tag="LLC22_000610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA/RNA nuclease SfsA"
                     /protein_id="HBK5433910.1"
                     /translation="MKYQQVEIAFFIDRPNRFIAHCMKKDGEIIIAHVKNTGRGKEVL
                     IPGAEVAIVFAPGPKRKTAYDLIAVKKKGDWFNIDSQLPNRLAIDGILDGTILLPGLT
                     GPFTVYKREVTYLHSKFDIYLETVVGQKAFVEVKGMTLENKAIGAFPDAPTLRGLKHI
                     GELTYAAQDGYAAYVLFIAQFEHLHLATIHEEMQPALADMVRHAQQSGVQILAYNCQV
                     SADEVTVKQAIPFDVDIPFEDPIQ"
     gene            39684..40697
                     /locus_tag="LLC22_000611"
     CDS             39684..40697
                     /locus_tag="LLC22_000611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5433911.1"
                     /translation="MINLGIIGTNWITHQFVQAALSTKKYELTAVYSRHLEKAQEFGS
                     HYEGDIEFATDLKTFFNITHMDTIYIASPNSLHFSQAKQAILAGKNVIVEKPAFSTPK
                     EMDEIIHLANEHNVYFFEAARNIHESGFKKIADYLPLKDEIIGANFSYMKYSSRYDQV
                     LDGEEPNIFSTHFSGGALMDLGVYLVYAAVAWFGMPKEVHYFPRKISTGVDGLGWGIL
                     RYENFDVSIQPGKIGDSYLPSEIYFDSGTLVMNGVNAIEQAQFHDRAHKEIIDLAVTA
                     AENPMADEAEDFANVMAHPKDPAWGLLYEEWIELARNVNQVIYDLRKNGGIKFDADNE
                     EDF"
     gene            40697..41974
                     /locus_tag="LLC22_000612"
     CDS             40697..41974
                     /locus_tag="LLC22_000612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK5433912.1"
                     /translation="MNEFVQVFPENWQKKYEDKGFISPSLIQRAVFQPLSNKQSIVAV
                     SPTGSGKTLAYLWPLLLNVEPGEASALVIFASSQELAIQVADVAREWGKDKELKVQSL
                     VGGANVKRQIEGLKEKPEILIGTPGRILELMKAKKIKAHQVKTMVFDEADQLFDAGNS
                     QIIDQILHQAPTEYQLAFFSATADRSLESIEKITGKTFETIDVTAEDDSRKGLRHYFL
                     RVPIRKKDDYLRRLTHIEDFHGLIFFNQLTELGVMEEKLLYRGVPVGSLASDQNKLLR
                     KAALEQFKKKMVRALLTTDVAARGLDITGLPYVVNAEVPLSEEAYLHRSGRTGRMGNE
                     GIVITLVQDNNLRDLKRLLRPSNITLEEIFLYGGKLQTEQPTKEDAAPAVNKKYAKTF
                     SGKEQNPEYNKEKIRKKVKNKSKKERNKGARRK"
     gene            42037..44739
                     /locus_tag="LLC22_000613"
     CDS             42037..44739
                     /locus_tag="LLC22_000613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5433913.1"
                     /translation="MKERQEEILQLLTENQQGLTASDVAERLTIDRSNASRYLSELYK
                     AHHIVKTAGRPVVYSLPTEKSKSDEVHVDSSTQVTFETLVGENDSLKVSIQQAKAAIL
                     YPPRGLHTIIFGETGTGKSMFAECMYHFAIDSEMLSADAPFVSFNCADYAQNPQLLFG
                     HIFGIKKGAYTGAAQDSPGLIAKADGGILFLDEIHRLPPEGQEMLFTFIDKGIYRPLG
                     ESAQVHEASVQIIGATTESSESFLSTFNRRIPMAITLPNLASRSLDERYEIISLFIKQ
                     EANRLNQRIDIEKEAILAFMLYDAEGNIGQVKRDLKLVCAKSFLHYRTHHEKKLIIRK
                     EELSLQVQKGLLKIKEIPERLDRFMDSKSQYLTFEPGFADVVWSQDPERNMQVYNDIE
                     EKVTSLSETGVENIDLETLISKDVDAYFQTYVKELTKSSIPKDLLPDEIWRLTNQLYD
                     VAEKRLDRIYNEKARFAFALHLQSTLDRVREGHMIVHPDLNNVRKNFKREFQVAIDLS
                     TIIEEEEQVEIPFDEIGFISMFLSINLGESEPVKENKVDVLILMHGRQTASSMLEMAQ
                     ELLGTKVGKAFNMPLVMEVQTMYEEVLQYVKNYQEHLTNGLLLLTDMGSLNTFSDLIY
                     EETGIRTKAITMTSTMIVIEAIRMASVGRSLEDIYQNIQLSFESIVRDQFKAEKSETL
                     QRKKAVIVTCFTGEGVAAKLYQRIMPVINQNKVELIQMQFLERESFKKHIDALLEEYE
                     IKAIAGTVDVDYQNIPFFSAYDVFDDEKLNILKRIADDEIPTAKIVDSLAGSLSDVFS
                     IDELIRSLQKTVQQIQTDLSIIVEPGVDTGIVIHLAFMLDGLIKQESHRQFEKLSIFS
                     KIYRLEMDIVRANLMALERKYQVKIPEDDIAFLTQMFLENKIKK"
     gene            44891..45208
                     /locus_tag="LLC22_000614"
     CDS             44891..45208
                     /locus_tag="LLC22_000614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5433914.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEEKGMEADIFAVSASDA
                     DNNLESKNVDVLLLGPQVRFMKAQFEQKLAPKGIPLDVINMQDYGMMNGEKVLAQAEN
                     LMK"
     gene            45238..45558
                     /locus_tag="LLC22_000615"
     CDS             45238..45558
                     /locus_tag="LLC22_000615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK5433915.1"
                     /translation="MEDQQNLEAIMGLIMFGGNAKSDAMEAIAAAKIGDFELADRKIA
                     DAEESLIQAHHAQTDMLTQEAQGNHMQVTLLTVHSQDHLMTSIAFTDLAKEIIELYRR
                     VYSE"
     gene            45666..47126
                     /locus_tag="LLC22_000616"
     CDS             45666..47126
                     /locus_tag="LLC22_000616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5433916.1"
                     /translation="MNGLSSWMEKYILPVAAKIGAQKHLVALRDAFIGTLPATMAGSV
                     AVMINAIIRDLPQQFNSTYADSLAADKGIFAVLNVIIGINGFVWNGTLAIAGLIFAFS
                     WGYNLARAYGVNDLAGGIVGLATLIQGISFGPALSAALDVNVPSNVADAINSSEIGAT
                     IADGTLSVGLWGWLKLDHLNGNAYFTVMIMGAISVIIFCKLMLANITIKMPDSVPPAV
                     SKAFAAILPATIALYVIAIINYIVGRVADGQLIIDLVQKYIAEPFLGLSQGLGAVLIV
                     TVFVQVFWFFGIHGPNVLAPVLEGIWGQAQLINIDIFQKGYNGKTGTPAVLDAIEDGK
                     AYMWVRGSFDAFAWFGGSGGTIVLLIAILIFSKRADYLTVAKLSIGPGIFNINEPVMF
                     GLPIVLNAIMFIPFLIAPVVATAIGWTATYLGLVAPVSQQVTWVVPPFLLSFLATGAD
                     WRAPIVTLVCMVVTFLIWAPFVISANKMDPAAGEQQ"
     gene            47194..47415
                     /locus_tag="LLC22_000617"
     CDS             47194..47415
                     /locus_tag="LLC22_000617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433917.1"
                     /translation="MITIASAMQQDEIKELLEGYNEEGMTFTFKEKQGIKLFFETSAE
                     DPEVAAKKAKELIKAQPWGTVLYFQSTAV"
     gene            47446..47628
                     /locus_tag="LLC22_000618"
     CDS             47446..47628
                     /locus_tag="LLC22_000618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3188 domain-containing protein"
                     /protein_id="HBK5433918.1"
                     /translation="MIKNGLFLCSIGSLIVLYSLNPHSQRYDLYSMVTGLFLTGLGIY
                     FFMKGKKREEAKEKNN"
     gene            47628..48041
                     /locus_tag="LLC22_000619"
     CDS             47628..48041
                     /locus_tag="LLC22_000619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3284 domain-containing protein"
                     /protein_id="HBK5433919.1"
                     /translation="MEITKKLNIPASFFYDKVMDSVLFDVRKATGKSVTRKQLKNLEY
                     VKQFSQNNRARIKIEEVIENQSYKFRTSTTKNEFVVHYQIKPLDDSTCEVHYTEKMES
                     YGMLQKLNDMLLGTILMYFKRRRFKKMLDMIEATY"
     gene            48164..49345
                     /locus_tag="LLC22_000620"
     CDS             48164..49345
                     /locus_tag="LLC22_000620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5433920.1"
                     /translation="MTNKVRELGVSSIEEMFDLATYAFNGADTPERRERFRTLAENSW
                     NYGFFDEEDRLTSQVMATPFPVNFYGQEYLMAGIGYVASYPEARGQGGINQIMEKILE
                     DCRDRKVSLSYLAPFSYPFYRRYGYEQSFDKISYQLNSRDVPFIKKKSGKIKRMDFED
                     AKAAIRRIYEQMPENQRAGLKREDWWYTYKFKQKGNYQFALHFDDNEEATGYIVYQLA
                     TSSFIIAEWGFLDHDAFCSLVRFVSSHNGAFETFEYSCGYGGNDQNYLLENPFASVMI
                     TPYMMARIVDISLFLENYPFKKRQAAFALQIEEDHYAKWNEGIVEVTIENGKNHLSKV
                     EQTKLPIVRGSIQHITQLLLGYRKVEELVFQERIQVTKEYEETLSSILPQQQPILNDY
                     F"
     gene            complement(49416..49580)
                     /locus_tag="LLC22_000621"
     CDS             complement(49416..49580)
                     /locus_tag="LLC22_000621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433921.1"
                     /translation="MNDKPKEKVYAERLDSSKKNREKITKEAIQDHKKENPKTKENKK
                     FKFTKKEDLL"
     gene            49734..49807
                     /locus_tag="LLC22_000622"
     tRNA            49734..49807
                     /locus_tag="LLC22_000622"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:49768..49770,aa:Arg,seq:cct)
     gene            complement(49876..51015)
                     /locus_tag="LLC22_000623"
     CDS             complement(49876..51015)
                     /locus_tag="LLC22_000623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5433922.1"
                     /translation="MARLVKRGNSWQYEISYKKDDGKYTKIRKSGFKTKGEAKDAANE
                     LEYNLNKGLKGDRKNLLLSDYFEDWMQLYKEGTVSPITYRKYEDTLMNIKKYMPAVLI
                     SDLDRVGYQRFLNKYAKDHVKSTVIKFNNHIRASLKDAVEEGLIPFDPTRKAVIKGKD
                     SLKPKEDKYLDYDQFKSLMKLVEENLSAQYSSPMLVLVAGATGMRFAELLGLTWEDID
                     FEDQIITINKTWNYKLNEWGKTKNETSNRKISIDKHTIDLLKKFKINQKELFENFEIK
                     NPHNFVFFNLKNGLVSSNAVSKYLRKKLKELGIEKQFTLHGLRHTHASILLYQGVNIL
                     SVSKRLGHSSLETTMSTYLHIVRELEDQDKEKINTVFDSLYKNDN"
     gene            complement(51314..51949)
                     /locus_tag="LLC22_000624"
     CDS             complement(51314..51949)
                     /locus_tag="LLC22_000624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433923.1"
                     /translation="MDNSNEKLTKKEYLELIVEGGIGAIPYIGGVVQSLYFGSKNEKR
                     FKRIEKFYKNLNESLENIRDQIPEDVFNLENKDQLIGIFEGINDEVEKSKAQNKIDMY
                     KNLYKNCLLRINSASWDNEEYYLLVLNQLTSIEIQLLACLMSRGNENFTGNISMSGYS
                     QELIDGSLNRLSDFGLLEKTISSIVLGDVGKQNMGYKISHLGIQFINSTLT"
     gene            complement(52062..52697)
                     /locus_tag="LLC22_000625"
     CDS             complement(52062..52697)
                     /locus_tag="LLC22_000625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336314.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3221 domain-containing protein"
                     /protein_id="HBK5433924.1"
                     /translation="MDGIFGFTGIVLFIIGLIMLIVRFIKKTNKKTPMILLIIGIIFT
                     TVGFSLSSSNEANDNNKQESSSSDTQTTTSNSSNKSLTQFEEFLETNNHDWGAFLDSY
                     YSITPATEQNTAFTKYISGKTYTFEGTVIESMTTRIAIIADKEYDDKSWNDISATPKV
                     SYVIFAKDLNNADTFTKGDKVTFTGEISSRGSNIEKSYAQWDMINSKVSKK"
     gene            complement(52731..53192)
                     /locus_tag="LLC22_000626"
     CDS             complement(52731..53192)
                     /locus_tag="LLC22_000626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SHOCT domain-containing protein"
                     /protein_id="HBK5433925.1"
                     /translation="MEKEILIKSPGKTLIKVTDDSISIIRKGFINLVNQGIKGEKTIP
                     FKNISAVQLKKPGMSNGYIQFTLLGGNESRGGILAATKDENTVMFTKKYWNEMENLKK
                     YIEKQQSILDNNSKETQISSADEIKKYKELLDEGIINQEEFDFKKKELLGL"
     gene            complement(53322..53753)
                     /locus_tag="LLC22_000627"
     CDS             complement(53322..53753)
                     /locus_tag="LLC22_000627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326797.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ImmA/IrrE family metallo-endopeptidase"
                     /protein_id="HBK5433926.1"
                     /translation="MYLKLKEMLSEYNLKVVYMEMKEPGFYYPKPRIIFLNENLYGET
                     AEAFHLSHELAHFSASHFEFSVLYDTSTTFHSKFETEADKIAILILLNIYIENELTDE
                     SQFNLEKFMEYYSIQNKLRYTCYAVCQCYFKKKYSYARQYV"
     gene            complement(53771..54091)
                     /locus_tag="LLC22_000628"
     CDS             complement(53771..54091)
                     /locus_tag="LLC22_000628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296612.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5433927.1"
                     /translation="MNTYEIIKDLAKRKKISIRQLEINFGYSNGYLAKWKNNTPNSDE
                     LSRIADYFDVSVDYLLGREERETPKHVDLSEDDTVFSFDGKEISKETMRKAIAIAKAL
                     EENE"
     gene            54390..55166
                     /locus_tag="LLC22_000629"
     CDS             54390..55166
                     /locus_tag="LLC22_000629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage antirepressor"
                     /protein_id="HBK5433928.1"
                     /translation="MNTPQIFNFEQNEVRTILVNDEPYFVGKDVASVLGYSNTKDALS
                     RHVDLEDKMGSRITTSGQSREMTIINESGLYSLILKSKLPSAKKFKRWVTSEVLPAIR
                     KHGGYLTPEKVEEALLNPDTIIQLATQLKEERTGRLIAEQKIAEYEPKISYLDSILSS
                     TDSVTISQIAADYGMSPQQMNKLLHKLGIQKKVGNQWLLCKKHMNQGYTKSHTTEIPK
                     ADGGTKIVMNTKWTQKGRLFIYELLKKEGYYPQMDLEEIG"
     gene            55181..55384
                     /locus_tag="LLC22_000630"
     CDS             55181..55384
                     /locus_tag="LLC22_000630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433929.1"
                     /translation="MTDIAEITQRDREKIKEYVESSKFLTYTMLAERFGISKSYLSLI
                     LNGKKTSAEANRIIDSIITMYEL"
     gene            55400..55738
                     /locus_tag="LLC22_000631"
     CDS             55400..55738
                     /locus_tag="LLC22_000631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF771 domain-containing protein"
                     /protein_id="HBK5433930.1"
                     /translation="MQYLEAKIPIPEGYVIISQVDYEELKKADDTGRWMTLPEVLERI
                     NRKYDWFTSRVLKNPRYRNIIDIEKNKNGFVYYPVEGRDTYLFLRSKTLEFLETNFSE
                     ILRRQADGKI"
     gene            55725..55904
                     /locus_tag="LLC22_000632"
     CDS             55725..55904
                     /locus_tag="LLC22_000632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433931.1"
                     /translation="MGKFNRALVFSAPLIIYALGLWGSRQALIGTIVYMVWIFMGLDE
                     AEAEYRAKKPTEGAD"
     gene            complement(55947..56417)
                     /locus_tag="LLC22_000633"
     CDS             complement(55947..56417)
                     /locus_tag="LLC22_000633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433932.1"
                     /translation="MSIISFILSTFLTGIKIKGMRPQLEVELNASYFAADMIYTKVII
                     SNYSTEPAMLVNLELSSANLNRRWSATPFKKLIAKGGSVDDNRIYSEAVPLNIPPKSA
                     ISCYLAFEVGKINFNKLLNHQTKMIFTLNRTQIHKIVDIKNTNFPIEKLVKELN"
     gene            56504..57202
                     /locus_tag="LLC22_000634"
     CDS             56504..57202
                     /locus_tag="LLC22_000634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage regulatory protein"
                     /protein_id="HBK5433933.1"
                     /translation="MQELVILKNKEAVTTSLQVAESFEKKHQHVLRDIDALKKDVSNF
                     GQMFVEGNEPDSYGRNRRVFFISRDGFFLLAMGFTGKKAIYFKQKYIEAFNEMEDVIR
                     KNTVPQTIEDMMIYQLEEMKDVKKDVSMLKDTMRISGQQEFEIKQKGNMKVMGVLGGK
                     ESRAYEEISKKVFSKFWSEFKRTFSIPRYGELPRKRFDDAVSFIEMWLPETAIRMEID
                     QLNRQQRLFGDDNE"
     gene            57380..57721
                     /locus_tag="LLC22_000635"
     CDS             57380..57721
                     /locus_tag="LLC22_000635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433934.1"
                     /translation="MEKELSTLDQYLIDPDWGKPKIEETSGRKIRRNLLTNEELAWDQ
                     DDLGNHVTIWDHVYLIHLSKHSNKPEYIYVIEDGLIDALEEYDRDNLIDISYYGPGKK
                     YIAEMEAEFDE"
     gene            57714..58385
                     /locus_tag="LLC22_000636"
     CDS             57714..58385
                     /locus_tag="LLC22_000636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1071 domain-containing protein"
                     /protein_id="HBK5433935.1"
                     /translation="MSEIKGTTNFEKLFSRKLNKILKKKGNFDYLSWAHAWEIMKKND
                     PQATVTINEYKHYRVVSGTHQDFLVEEYKPFLMDETGTYVSVSVTVKGHTETELFPVL
                     DYRNQPVVKPNAMQINNSLKRCFVKALALHGLGLYVFQGEDIPTPPRIDTKKLNMLET
                     ILEAFNEQMGKDMTKTLIEYVNEQTDKLGLLADNVETIEQLSYEQCALMERAIAAKRK
                     ELDKK"
     gene            58391..59077
                     /locus_tag="LLC22_000637"
     CDS             58391..59077
                     /locus_tag="LLC22_000637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347917.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433936.1"
                     /translation="MFKPLIDSYSAVLKKFKGKDISATINEEVNIDRLKTMYDGYDGD
                     RVIEIRFIDPRRFTVQQRNFIYALIGDIFIDTGMPTDFWKEFFYFRFEGVTGRKISLK
                     DESNTTVSDANVLANIILDFIFEHHIPFKEGYEILPANQEYYFYKCITKRVCCICGKT
                     GADIDHFDKALGRRKRKEVDHAEYTFAALCRIHHTEKHKIGVINFKNKYQIKGIKLNQ
                     KTIKKLNIGG"
     gene            59080..59829
                     /locus_tag="LLC22_000638"
     CDS             59080..59829
                     /locus_tag="LLC22_000638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433937.1"
                     /translation="MTEHRSYYAIIPANVRYDKRLKPNTKLLYGEITALCNERGFCWA
                     GNEYFADLYGVNKETISRWVSDLIKFGYLNREIIYKEGTNQIINRYLRINQYPIDEKR
                     NTPIDEKVKDNNTSINNTFNNTKEYIRELPPSKKSKAKPVRHKYGEYKNVLLSDEQME
                     KLKTEFPNDYQERIERLSEYCESSGKTYKNYLATIRSWARKEKSEPKNASSGYKRTGR
                     REKLPEWAIDQEAYLKKKALERANRQSKAPF"
     gene            59841..60110
                     /locus_tag="LLC22_000639"
     CDS             59841..60110
                     /locus_tag="LLC22_000639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433938.1"
                     /translation="MKIDYLELINEIANYKKGEELDVLRDVYDQLEEAGIEGIKNDRS
                     SWSKLRYYFALYIDGTQLRNLAYTKLLFIDCVKGLQKHLNELEQV"
     gene            60116..60280
                     /locus_tag="LLC22_000640"
     CDS             60116..60280
                     /locus_tag="LLC22_000640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433939.1"
                     /translation="MDLKTFTAQIELMHQEALRQSVSYEDKWLNTFHGGRESALDQVL
                     KLLKGECRDG"
     gene            60273..60572
                     /locus_tag="LLC22_000641"
     CDS             60273..60572
                     /locus_tag="LLC22_000641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433940.1"
                     /translation="MDKKAAMQRIIELTYSEDWQEDKKIVAEVQKLGKSMWTEKPKRR
                     TPRKIAIWHGDRILVTGTAKQLSEITGLSKNIIWDRARSLWIDSKGRQFRYVEEK"
     gene            60572..60874
                     /locus_tag="LLC22_000642"
     CDS             60572..60874
                     /locus_tag="LLC22_000642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBK5433941.1"
                     /translation="MDELIAKVEQWAKDKGLDQADFSKQMLKTVEEIGEVAASLARKD
                     EHGLRDGIGDVVVTLIILAMQNDMDLYECLDFAYDEIKGRTGKMVNGVFVKSSDLK"
     gene            60914..61279
                     /locus_tag="LLC22_000643"
     CDS             60914..61279
                     /locus_tag="LLC22_000643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433942.1"
                     /translation="MIDAKQVQKQKDGMLMFEAYVLPFLNQFEVLECSASGEELEYVV
                     IRETKENVQKLNEFLCTINCWDMIAPGFLCPAMGEFLEYCRLEDAGTLDLAYLVYNYL
                     NINTDHLWFGTAERKWVVR"
     gene            61769..61909
                     /locus_tag="LLC22_000644"
     CDS             61769..61909
                     /locus_tag="LLC22_000644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433943.1"
                     /translation="MNEIAADHELSETALIDQIELARQYFVPYADTWSKHKNDIIFPE
                     EQ"
     gene            61906..62094
                     /locus_tag="LLC22_000645"
     CDS             61906..62094
                     /locus_tag="LLC22_000645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433944.1"
                     /translation="MRATDPVIILEEAKFIWTHEEIEQARLLFSQGVKPSKVAEIMGQ
                     KILDVGLLLLHLAEKNLI"
     gene            62102..62296
                     /locus_tag="LLC22_000646"
     CDS             62102..62296
                     /locus_tag="LLC22_000646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433945.1"
                     /translation="MMIQLAGIQTGKIYFSGESKSEANQWLLKTYTNNKKLRKKYPDL
                     LLKDDQIMPEPMILTRKEGS"
     gene            complement(62329..62541)
                     /locus_tag="LLC22_000647"
     CDS             complement(62329..62541)
                     /locus_tag="LLC22_000647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433946.1"
                     /translation="MNINNLVKLVEQRFKESGLEQLKKDNSPELFSNFTEDDIPTLKQ
                     LKYYSDYWTQTRENELNLEKLIIKKK"
     gene            62666..62869
                     /locus_tag="LLC22_000648"
     CDS             62666..62869
                     /locus_tag="LLC22_000648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433947.1"
                     /translation="MVKVREQFKIVSDEDNVYKIKIVNINEYREADHKYLVDLYMNDK
                     YLGEGFCGDSLFDDERILKEETE"
     gene            62866..63138
                     /locus_tag="LLC22_000649"
     CDS             62866..63138
                     /locus_tag="LLC22_000649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3850 domain-containing protein"
                     /protein_id="HBK5433948.1"
                     /translation="MIHELKILPEYFEAVTSGRKQFEIRKNDRDFKVGDQLILREYKK
                     YIKHELPGLTRPTFSYTGDSYKAEITYITDYMQKSGYVVLGIKGVN"
     gene            63139..63324
                     /locus_tag="LLC22_000650"
     CDS             63139..63324
                     /locus_tag="LLC22_000650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433949.1"
                     /translation="MKVYILAITEGTWMFPVGSGKIYKSKTAAYKAFEKYKKENGGGT
                     NAKILVADNWHEEGERN"
     gene            63311..63658
                     /locus_tag="LLC22_000651"
     CDS             63311..63658
                     /locus_tag="LLC22_000651"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433950.1"
                     /translation="MNVIDLPVHFRGTNYFYASNLIQKKMSKDERKILANFYLVLKIE
                     QNVFSERRIVWEKQNQRLRRKNDVWNKRQSRMERLRKNKKATPFEIAAQYYSTIRGGV
                     CEISLVKRLPRTR"
     gene            63618..64094
                     /locus_tag="LLC22_000652"
     CDS             63618..64094
                     /locus_tag="LLC22_000652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1492 domain-containing protein"
                     /protein_id="HBK5433951.1"
                     /translation="MRFHWLKDYQELDEQILYLKWNLNKSKLELNRWVCGDLANVRIE
                     KNSRTSSLEENIQKIENELELLIEQKEEMLLLIDSFSGIDNQIVKMKYVDQMSLEDIA
                     ESVGYSSSYVRQRHAEIRKTLNFLDEYEHRQADRLKKENEIDFYNSEKYKEQLSLF"
     gene            complement(64240..64968)
                     /locus_tag="LLC22_000653"
     CDS             complement(64240..64968)
                     /locus_tag="LLC22_000653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4145 domain-containing protein"
                     /protein_id="HBK5433952.1"
                     /translation="MRGVLMLQEVNIKYRDRQNTETIYLPNSCPHCGNIMTPYVYFGV
                     SSYSAFDNDRIFGVLVQCINDECNKFYSLQFINTFNEDEGYSENILIKDYYRPPIKID
                     LPENIEKVSPTFVDIYTQATQAKSEQLEQIAGVGYRKALEFLIKDYAISKNSEDEDKI
                     KKMLLGKTIENYLNDFPKLQRLAKAATWIGNDETHYVRRHTNKDVHDMDAFIKSAAQF
                     IAADYDADLADQFINGNNFMPTTN"
     gene            65016..65294
                     /locus_tag="LLC22_000654"
     CDS             65016..65294
                     /locus_tag="LLC22_000654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303029.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433953.1"
                     /translation="MNDFHEAVLSIEVESSLAKVYKKAIEAENSPYRENWNGNHAHVQ
                     VENDDYRTGMNTLVISLLSHTLPNLQETIEWYERMGAKVIRTNYKGEN"
     gene            65296..65682
                     /locus_tag="LLC22_000655"
     CDS             65296..65682
                     /locus_tag="LLC22_000655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433954.1"
                     /translation="MAMIKIRTSISGTEYWDSEKKRTVVVPKDQEPNFEVKEEKGILS
                     DGKSFVAVNGELIAHSSEILDSDGNTAANFDGDEATNDQSTEDTDELDNMTAKELRAY
                     AKKHGIDIPGAIRAKGDIINLIREVE"
     gene            65679..66059
                     /locus_tag="LLC22_000656"
     CDS             65679..66059
                     /locus_tag="LLC22_000656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HNH endonuclease"
                     /protein_id="HBK5433955.1"
                     /translation="MKYCQFDGCTNKIAKGIYCTEHKRSSRSRKKKQQAKSVYHHENK
                     PFYRTQAWKDMRQFIYEREGGHCQRCGQFIFGKRAHVHHIVPIKDNELLKLDPNNLML
                     LCSKCHPIVENETEDKKVFPSYFN"
     gene            66171..66623
                     /locus_tag="LLC22_000657"
     CDS             66171..66623
                     /locus_tag="LLC22_000657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase small subunit"
                     /protein_id="HBK5433956.1"
                     /translation="MTTKAQRKAIIDEKVSAEKARILEIMNLSDLYTITLDPLIESYL
                     DIFEIYQHKYLLWKEKGFPETQKFTNKSGATNQSKHPLAQQVETWADKKMKALDLLGL
                     TNKAKTGRLIAGGSTARKDEEITRPEVKPVDELAAHRNKWRKKAGAEK"
     gene            66620..68347
                     /locus_tag="LLC22_000658"
     CDS             66620..68347
                     /locus_tag="LLC22_000658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="terminase large subunit"
                     /protein_id="HBK5433957.1"
                     /translation="MIEPGVNYADLFAKEVRKKPKKYPKTVRLAIDRWYQWKKRKDIW
                     FDVDRANEMMDWVESFIVHTKGEMVGKPFLLEPWEKFIYSWIYGWVKENEKGQIVRVT
                     REAYVQIPKKNGKTLIAVGSLGYAMYGEGALSVDCYACASDFAQAQYAAKPFAVTILN
                     NPILLEGTKIFRGPKGTVSSITYDYIHEDMAYSNKFIVQTKNIDNIEGSNPYFVLNDE
                     LHKQEKMEQYDNFKSAQISLPQPLMFNISTAGKGSSSVGMRVYREAKEVLKRDDNDSN
                     FVLIYEPNKNYDWTDRKVWEMCNPNWGISVDLSALESAFKTAQRSAHSKAEFLTKHLD
                     VFVNGADNFFEQDQVEPCLVTTQELGDLSGEPCYIGLDLSRTRDLTCVSLNFPTWDED
                     GKAVLKVKQLYFIPNEDLEFREKEDNVPYSDLAEQGFVEFCDGKMIDQDQILQYIEDC
                     MNLYDIQQVNYDPAMSDKLVEKLENLGLECVEVAQYPKVLNAPFDDVERLFYEKRIQF
                     DNPLFLYCTLNVVAITNINGQKAPSKRQSKKKIDGFVAFLCGHKETMNQMTDIDSDEL
                     DDYLSSIYR"
     gene            68411..69598
                     /locus_tag="LLC22_000659"
     CDS             68411..69598
                     /locus_tag="LLC22_000659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK5433958.1"
                     /translation="MEKRGYIEDIFGHYTRYGQRYVTDSSIMESSDVYELVQDISNQV
                     ALATPIVIGPDGNEVKDHHLLNILKSPNDYLTGFEFTKLETNTLLINGETFPLTDRDQ
                     LHLAYGVTTKINERLQEEFEMNGQKIPGQMIRHIKNIGTDSLKGAGIIDLARNTLEGV
                     LSAEKVLTDKYTKGGLLAFMLKLDAHINPNNSAQTKIVKAILDQLEGTQNESDHSVKM
                     IPLGKGYSIETLKSPVDDAAILNYLGVYKKDLGKFLGINVDTYQSLMKTDIEKAMMYL
                     HNKAIKPILKNKSEHYTALFFMPNSGYRVEWKINILDFVPYSTKTNIGYNIVRTGITS
                     PDNVAEMLGFPKQNTPETQAIYISNDLSRIGQKNATDDSLPTNDQDLKGGDGNEEEGN
                     SHD"
     gene            69570..70139
                     /locus_tag="LLC22_000660"
     CDS             69570..70139
                     /locus_tag="LLC22_000660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 family phage prohead protease"
                     /protein_id="HBK5433959.1"
                     /translation="MKKKEIRTIDITNLSTRSDEETHTRTISGYAAVFNSQTLLWDDL
                     SEVIVPGAFSKAISNSDVRCLFNHDWSNVLGRTKSGTLRLEEDERGLKFEVDLPDTTV
                     ARDLVKSMERGDINQCSFGFVPTEETWDYNSEPMLRTIHEVELYEVSIVPLPAYEDTE
                     AALRSRDELEKNVEERKKLIKKINQALEA"
     gene            70152..71516
                     /locus_tag="LLC22_000661"
     CDS             70152..71516
                     /locus_tag="LLC22_000661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage major capsid protein"
                     /protein_id="HBK5433960.1"
                     /translation="MDKELLKKMKARREQRLTELREKVESGELREADLEAVKEEIDSV
                     IDELNGIKDELGADSGTDETDDNTDDQSNSTDSDESRSGEDNDQEEDSDSEDSSENRS
                     GMITQQQRDGLLGSIKNGLEARAKMTKKQKDQQLRKAFANFVAGNISEAEARALGIEA
                     GNGSVTVPEVIASEVITYAQEENLLRKYGTVVRTSGDVKYPILVKKADANVNKKERST
                     DIAETAIQFDEILLNPAEFDALATVTKKLLKMSGVPVEDIVVEELKKAYVRKEINYMF
                     NGDDAGNENPGALAKKAVAFKKPLDLTASGAGQKLYDALIEFKNTPVTEVMKKGRFII
                     NRAALTAIEKMKTDDGFPLLRPFTQAEGGIGYQLVGYPVDWTDAADKKGEPDTPVLYF
                     GDFSAFKIQEVIGALEIQKLVEKFSGKNQIGFQIYNLLDGQLVYSPFEPAVYRYEITK
                     PVGG"
     gene            71518..71799
                     /locus_tag="LLC22_000662"
     CDS             71518..71799
                     /locus_tag="LLC22_000662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002395304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage gp6-like head-tail connector protein"
                     /protein_id="HBK5433961.1"
                     /translation="MEEQTKELSLEEKFKSHIHFEEGMDDSLLSFYLNMAKDYVKTAT
                     GGQQEYLILMVAGIAYEYRVSEDELDKAMNAMTPFIVQGAIQNAEETDQ"
     gene            71777..72103
                     /locus_tag="LLC22_000663"
     CDS             71777..72103
                     /locus_tag="LLC22_000663"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head closure protein"
                     /protein_id="HBK5433962.1"
                     /translation="MPKRQTNNLRWKAELLDIKTGTDGNDRPTTIYEFKRLIFYEELG
                     VTSQEKYLSQQAKTDVVRRIKVRWDKSITEKLSALKIDSVTYNITRIYTNPDAREMEL
                     SLAYVD"
     gene            72093..72431
                     /locus_tag="LLC22_000664"
     CDS             72093..72431
                     /locus_tag="LLC22_000664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433963.1"
                     /translation="MSISFDELKTALKSTKLAVFRDKARLGTMYPYIVYSNVSNSKKM
                     ASGKVYKKLPYYQVSFFTLGTEQDLVVIEQALQNAGIPYSDFTGIQGDENDDTVTNYY
                     TYVRCVENAK"
     gene            72421..72786
                     /locus_tag="LLC22_000665"
     CDS             72421..72786
                     /locus_tag="LLC22_000665"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK5433964.1"
                     /translation="MPSNKNGFSEISDYLGNLSKVDPKKLSLESLEEAANFYLKQLLP
                     NIPKSLLKKKHMRDQIKVVVENDQVKVQFEETAFYWRFAENGTTNQRAQHFASGTYEQ
                     NKEKIEEIMTRKILDLWEG"
     gene            72793..73419
                     /locus_tag="LLC22_000666"
     CDS             72793..73419
                     /locus_tag="LLC22_000666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5433965.1"
                     /translation="MGKQDTFYFEGLDDILIAMMATPDSVGTAPTYSEVLRLPIATKI
                     GVKGNGTALEKWASSKMFRRVSRETKHELALDHVGIPIEVMDEIKGLVAKSGVTFSKN
                     TAREFPYFAFGFIGNIENGGKKAVWYPNTQLSNVIDEEYATAEEETKIDDVTANLVSI
                     GLKYNNVMYASFDSNRDGASLELFNKFIAQPVYDEEQWKTLAKVGGAG"
     gene            73419..73883
                     /locus_tag="LLC22_000667"
     CDS             73419..73883
                     /locus_tag="LLC22_000667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433966.1"
                     /translation="MARLSDYGIHVEDLKNSAVVIIQGAEFPISFTMQTMEFIADVYG
                     GDYSQFESDMNAMLSKKEGQISSANLSPSDLKIMRALIYAMLRTGGLEEDPETIFKFL
                     GMSGEVLSAYSTCMEIFASQTFQVEDLKKSKKPQDFQKAQAKRKKNKKNRKR"
     gene            74078..76387
                     /locus_tag="LLC22_000668"
     CDS             74078..76387
                     /locus_tag="LLC22_000668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail tape measure protein"
                     /protein_id="HBK5433967.1"
                     /translation="MAGKESDVVLNFKTNGEVSYSKTIKEINKEMNLAAAEYKNQVSA
                     MDKDATQTEKLRAAKQKLEKQLGLAEQRSQMLREEYEKSVKETGEYSAESEKLYKQLL
                     NSETGENKLRTALEQTNDALKEQGDVSVDTAKKLQKIEETGEKVKGVGEKMSVGVTAP
                     IVAAGAAGLAAFGEVDEALDTIITKTGATGDQADRLSQSFKNVGSNTHLPLQTVGEAI
                     GEVNTQFGFMDKKLEDSTNYLLQYAEINDTDVSQSAISARQAIDAYGLEYDDLNSVLD
                     VTTKTSQNTGQSVDDLMQKAIDGAPQIKQLGLSFGEGVTLLGQFEQSGVDSSAALSSL
                     SKATVAYAKDGKSLSQGLEELQDKVKNAGSETEAINAAAEVFGTKGGPRMADAIRRGT
                     LNLEDLAKTAGESGGAVGDTFDATLDPIDQADQAMNNAKLAMADVGEAVQVSLLPFFE
                     KATSLLQEFSKWWGSLDQDTKNWIITIAGIAAAVGPVLIVLGSLMGSVTKIVGEVKSF
                     IGVWQGLAGLFGMSGGWFALAVIAIGALVTGLIWAYNNVKWFHDGVNSFFKGVSDVAV
                     EIFNFLSGYFGGFFDGVIANFNNFYNAGKRIFSGFLDFITGVFTGNWSKAWQGLVDIF
                     GGIFDGIVAVGKAPINAMIGLINGFIGGLNNIKIPKWVPGVGGKSFSISKLPYLAQGG
                     HLINGQAIVGEAGPELLTAKNGKTTVTPLSDEEKRKGISGRVSGGSIEQHIHIGKVDA
                     NNPSELDRMNRKFAKANKQAIRDLGGVPI"
     gene            76399..77103
                     /locus_tag="LLC22_000669"
     CDS             76399..77103
                     /locus_tag="LLC22_000669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5433968.1"
                     /translation="MNPDEPNFIWKNRNAVIDMNCIIEAELPDIMPNKRYETYTIQGR
                     SGELTETFDDYEPFDLEIEGITIPHSKLREVKRWLTGKSQLITHNDPDKYLEAICSMD
                     KEVPFENEWGFFYTFDVTFRCQPLKRKIGEAPKIFHSSVMDIFDHGDEIAHPYLEIES
                     NGGDITIAVGDKSLTILNTLAATIVVDTQLGKAIQEGLNLFTRGDWPVLQPEWNQVKI
                     SGKFKEVRFWNRSVYL"
     gene            77100..79859
                     /locus_tag="LLC22_000670"
     CDS             77100..79859
                     /locus_tag="LLC22_000670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5433969.1"
                     /translation="MTQEFIYAYKKMPDDLSVNGASLVDWEDLPEINRVLNGQYRFYG
                     NYSRSGQYRSYLKKGNFIKAKVPDGSWQYFEIYNVKKNLTSVSVTARHIGFMANKNFI
                     VKSFTDNGNGSQIMTNLKNSLAFDQKFNYLSNVGTTHQFTARQVAPVEAIIGSNNGNQ
                     NLTGVTSAELDMDNYDLKLVKQIGSDNGFRIDFGINLEAIEEEIDEESIVNSLYLVGG
                     VPDNDYDEDKEPIEYGYLEIDGVTNENRRIAKRENGDCKTVDELIKWGKTLFDNDRIH
                     EPKATHTVSMVALEHTLEYGDMYQELASLHFGDVAHVRAKELDIEIKERMVEYTYFPT
                     LGKYKDIVLGNDLSLYTSAVNTQAQELKKKIDNRTETLVQNVLNATAWITGNSGGHVV
                     FRPEKAPSEILIMDTPNVANAKRVWRWNLNGLGYSDNGVNGPFGIAITSKGEIVADFI
                     KVGTINAEVFETSFNAYGDVLKLVKGTLQIWNENKKIMELTKKGMEFWNRKESIGTIG
                     TTDSAGNPFPNAVTPTPLEENSLVIRTNGDGKYILISPTAEKGFVLLGNGKAYYFGDL
                     DIQGKLTVRGKEVIPGQNGGPSGGGETPGGYPDELKTDAEKRAWRIYDILCNNGFTKQ
                     SACGILGNIQQETGGTFDPDTVQIGGPAYGLVQWDGSSYPLVGPATWDGKVYVQNLFN
                     AAGIKEPITSLDAQVRLLIWTFTNGQWMGVVQPTTVDGFKACTDPRQAAYAFERNYER
                     PAATHPERQDYAVNWYNKFKDLKPGGATGEAGLKHLESLIGQRIGNGQCYGLSAEYSG
                     YLGGCGMGAGTKYGLTHVIGNTSAASDIGIAYDWSAVGWKVIQNPRYDQLVVGAIINW
                     ARGGQVGSWFADGTYGHTGVIRGLANGRMQTYEQNTELGMICGKLDRQYYSASAISSI
                     VIPPK"
     gene            79872..>80101
                     /locus_tag="LLC22_000671"
     CDS             79872..>80101
                     /locus_tag="LLC22_000671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBK5433970.1"
                     /translation="MAKWNVILSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETRIVDAKKGKI"
BASE COUNT        27132 a        13158 c        16845 g        22966 t
ORIGIN      
        1 aaataaaagt tgtagtggag gctacgaagt ttactttgtc tttttacact taatattttt
       61 ttgccaattt ggaatcagga tgttttgata actatcgttt tcaattgatg gaagctatat
      121 tgtttgctat cagtgaaata attatatggt aaacagtgtt ctttttcttg tttccattat
      181 aaaaatcgta tcgggatttt tcgttctttt aaattgaaca tttctatcta tccgcgtgtt
      241 atcaacaaaa caaaatcagg taaatagttg acgaaacaga aataaataca tagtattatg
      301 ttttgaagcc taagtacaat agtctataga aaaggagcga taccattggc aaaacgcatt
      361 gaccgaattt atatgtatgt caaagaaaaa accgctcatt taacaaaggc agaatatgat
      421 caaggagtaa caacacagga aattgctgaa gtgttaggga ttcagcgaac aaatagcagt
      481 aaagatctga atcagctagt gcgcgaagga aaactgataa agacagacgg acgaccagta
      541 cgttacatat atcaaacact cgttacgcac gtaaagccag ttacaaaaca tgtagtcagt
      601 tacaaagaaa cgccggtctc tgaagaaaaa aatacactcc aaatagatac taaggatatc
      661 tttgcaaaaa tcattggagc taacggcagc atgaaaaatt cagtggaaca ggcaaaagct
      721 gcgattttgt atccgccaag aggattaaat tgtttgatta caggacctac cggatcagga
      781 aagacttatt ttgcacacgc gatgtatcat tttgcaaaag cgcatcatgt aatagatgag
      841 gaaacggaac tgattgtttt caattgtgct gattatgcca ataaccctga gcttttgatg
      901 agtcatttat ttgggtacgc aaaaggtgct tttacaggcg cagatgaaga aaaaatgggg
      961 attatcgatc aagcggatgg cggtatgctg tttttggatg agattcaccg gttgccgcct
     1021 gaaggtcaag aaatgatctt ttactttatg gatcatggaa cttacagtcg tcttggggaa
     1081 acaacgaaat cccatgaagc aaatgtacgg atcgtaggtg cgaccacaga agacccaggt
     1141 tcttctctat tagaaacttt tgttcggcgt atcccaatca atatcaaact tccggctttt
     1201 gaaaaacgtc ctgcaaatga gaaagtcgat ttagtaaaaa tcatgattgc ccacgaagca
     1261 aaccgcacgc agcgaaagat ttctttgaca gaagatgtag caaaagcatt gatcggcagt
     1321 gtgacctatg gaaatatagg acaattgaag tcaaatatcc agttagtatg tgcacgagga
     1381 tttctaaatc atatgcaatc acccgaaatc tcgatcacaa tcgatgattt gacagaaggg
     1441 attcgtagcg gattgattca attagcaagc aaccgcagtg caatggcaga gctttctaaa
     1501 atattggagc caaagataac tgtagcacca aatgatacga tcatgaaaat ccaatcggac
     1561 tcctatgagt taccttataa tctatatgat atcatcggag ataaagcagc tttactgaag
     1621 tcggatggtt tggatcaaga agcaatcaat catttcattt ctacagatat caacatccat
     1681 ctgaagtctt tctataaaga ccatggtttt tcttttaatg cagacagcaa attagcagaa
     1741 tttgtagatc cgaaaatcat agaagtgacc aatcagattt atgtaatggt caaaagatct
     1801 ttaccatatg agtttcagca aaactttatt tatgctatga gcttgcatat cagttctttt
     1861 ttgaaaaaaa tcaacttagg agaagaacgg catacgaatg ataacatccg tgagatggct
     1921 tttgattttc cagatgaata tgctgttgcg aaagaagtgc gtagttatat cgaaacgtat
     1981 tttcaagtgg agattccaga aagtgaagac tattacttga ccgttctact cgtctcgtta
     2041 cgggcaaatc aagcaagcgg cagaatcggt gtagtcgttg cagctcacgg aaacagcaca
     2101 gcaagcagta tggtccaagt tgtccaacag ttgttagatg cagagaacgt acgagcagta
     2161 gacatgcctt tggatatgga tccgaaaaca gcattggacc gaattgaacg caatgtacaa
     2221 gaagtagatg aaggaagcgg ggtcatactc ttagtagata tggggtccct tgcgtcgttt
     2281 aattcgcaaa ttcaaagaga cactggaatt ccagtacgta ctgttgatat ggtaacaact
     2341 tctctagttt tggaaactgt acgaaaggtc tcagtattag ggacagatct agatatgttg
     2401 catgaatcat tgaaaaattt tcgaggttac gcagaaatat cttctgtaga atctgttcag
     2461 gaagcaaaac ctattcataa gaaaaaagct gttttggcta tctgcgcatc tggcgaaggt
     2521 acagcacaaa gaatcaaaga attgatcgaa cgagcggtaa acaagcgtca agaaacagaa
     2581 ttagaagttc tagctttgtc gattgtggaa gtgaaagaag aactgccagt tatccaaaaa
     2641 gaatatcaga tcatagctac tactgggatt actgatttga atatccaagc cccatttatt
     2701 cctttagaac gttttattga tcaaaatatc gaagtcattt tggatcagtt gctgatggaa
     2761 tcagaattgg aggaaactga attcatctcc ctagatgaag agtcagctaa aaatacgtgt
     2821 gttgagttta tctctgataa cttcatcttt attaatggta gtaagttaat cgatccaatg
     2881 tggcaatttt ctacacaaat ctctcagacg acgggaatcg gcgatgaaga atatggattc
     2941 aaaatcaacc tagtgatgca cacagcagga atgatcgaac gtattattcg gaatgaacca
     3001 ttgactgtgg aagaaaacga attgacaaat acaacgaatg atcctcttta tagccaattg
     3061 gcagcctcag ttgttctgtt ggaagatcag ataaaagtaa aagtgccgat agaagaaatg
     3121 tattatctgc tacgtctagt ccataatcag ttagataaaa aagaatacac tgtgccatga
     3181 atacacaaaa acgatacact tttatagtgt atcgtttttg tgtattggtt aagaatcctt
     3241 taaattcaat tagtgtatcg taaaaaagtt ggcacgcttt ttgcttatag tagtgtgtgc
     3301 taggaggtgg ttgttcacac agaaatgata ggggtttctg tgaagtagtg aggaagaagg
     3361 agttttgcag atggatattc gattggcacg tatagatgat cgtttaatcc acgggcaagt
     3421 cgcaacagtt tggtcgaagc aaacaggtgt tgaacgtatc attgtgatca gcgatgtagt
     3481 cgctcaagat aaattgagaa agtttctact aaaagaagct gcaccgccgg ggatcacagc
     3541 aaatgtaata accgtgcaga aaatgattca aatctatcat agtggattat tatcacgagc
     3601 aaaagtgatg cttttattca ccaatcccca agatgttgaa gcggttgtcc gctgcggtgt
     3661 acagttgaag tcgttgaata tcggcggtat gagttttact gaaggcaaat caatgattac
     3721 caattttgtt tcagtaaatc aacaagatat tgattccttt cgttacttga acagtcaaga
     3781 agtggagtta gagattcgaa aagtacctgc tgacaggaaa atccttttga tggaactact
     3841 agcgaaaatc aaaaaggtgt agcaagaatg gttgttggaa aaggtcaaat aattctgttg
     3901 taatggttag caattattaa tatttttgaa tttgttacaa caaaagtaaa taggaggtat
     3961 aaatatggta gggattatcc tagcaagtca tggacaattt gctgaaggaa tcttacaatc
     4021 cggttcaatg atctttggcg aacaagaaaa cgtcaaagcc gtgattttga aaccaagtga
     4081 aggtccagat gacttgagag ccaaattgga agaagcggtt gcttcttttg ataatcaaga
     4141 cgaagtgtta ttcttagttg atttatgggg cggaacaccg ttcaatcaat caaacacatt
     4201 attcgaagag cacaaagata aatgggcaat cgtcagcggt ttgaatttac caatgttgat
     4261 tgaagcctac gcatcacgct tttcaatgga atctgctcat gaaattgcag cacacatcat
     4321 tgaaacagca aaagacggtg taaaagtaaa accggaagaa ttagaaccgg cagaagcacc
     4381 gaaagcagca gttgaagacg cacaacctaa aggagcactt ccagaaggaa ctgtggtcgg
     4441 agacggaaaa atcaaatatg tattagcacg tgttgactca cgtctgttac atggacaagt
     4501 tgcgacagct tggacaaaag cagtgcaacc aaaccgtatt atcgttgttt cagatgcagt
     4561 atcaaaggat gatctgcgta agagactaat cgaacaagct gctcctccag gtgtaaaagc
     4621 aaatgttatt cctattagca aaatgatcga agtagcaaaa gaccctcgtt ttggaaatac
     4681 caaagcattg cttttatttg aaaatcctga agacgtattg acagctgttg aaggtggcgt
     4741 agacatcaaa gaattaaatg ttgggtcaat ggcgcattcg gtcggtaaag tcgttgtaag
     4801 taaagtattg tctatgggac aagaagacgt tgaagcgttt gagaagcttg aacaaaaagg
     4861 tgtgaaattc gatgtacgta aagtacctaa tgattcacgc gataacatgg atgatatttt
     4921 gaaaaaagca aaagctgaat tagcaaaagc gtaataaata atattaaaat ttataggagg
     4981 cttatcatgt ctattatttc aataatttta gtcgtattag ttgcctttct agctggtatg
     5041 gaaggtattc ttgatgaatt tcaatttcat caaccactag tggcatgtac attgatcggt
     5101 ttagttaccg gtaacctcga agctggtatc gtacttggcg gtacgcttca gatgatcgct
     5161 ttaggttggg caaatatcgg tgccgctgta gcaccagatg ctgcattagc atcagtagca
     5221 tcagcaatta ttttagtttt aggtggacaa ggtgttaaag gtgttccttc tgcgatcgcg
     5281 attgccgttc ctttggctgt tgcagggttg ttcttaacaa tgatcgtacg tacaatcgct
     5341 gttccaatcg ttcatttgat ggatgcggct gctgaagaag gaaacatccg taaggttgaa
     5401 atgtggcaca tcattgctgt atgtttacaa ggggttcgta tcgcggtccc agcagcagcg
     5461 ttgctattta tcccagcaca aactgtgcaa tcattccttg aatcaatgcc agcatggtta
     5521 acagatggta tggctatcgg tgggggaatg gtcgtagctg taggttacgc tttggtaatc
     5581 aacatgatgg ctacaaaaga agtatggcca ttcttcgtta ttggtttcgt tgtagctgca
     5641 atttctcaat taacattgat tgctctaggt gctttaggtg ttgcattagc tcttatttac
     5701 ttgaaccttt ctaaaatggg tggttcatca aataatggag gcggaagcaa ctctggtgac
     5761 cctttaggcg acattttgaa tgactattaa tcttgaagga ggaaaataaa atggcagaag
     5821 aaaaaatcaa attatcaaaa aaagatcgtt tagctgttgc gtggcgctct accttcattc
     5881 aaggttcatg gaactacgaa cgtatgcaaa acggtggctg ggcattttct atgattccag
     5941 caatcaaaaa attatacaaa acaaaagaag aacgttctgc agcattaaaa cgtcacttgg
     6001 aattctttaa tacacaccca tacattgctt ctccaatttt aggggttaca ttggctctgg
     6061 aagaagaacg tgcgaatggc gcgcctgttg atgatgtagc gattcaaggg gttaaagtag
     6121 gtatgatggg tcctttagct ggtgttggtg acccagtgtt ctggtttaca gtacgtccaa
     6181 tgctaggtgc actaggtgct tcattagcta tgggaggaaa tatccttgga ccaatcatct
     6241 tcttcttagg ttggaacatt attcgttggg cattcatgtg gtatacacaa gaatttggct
     6301 acaaagctgg ttctaaaatt actgatgacc tttctggcgg attgttacaa gacgtaacaa
     6361 aaggtgcttc aattttaggg atgttcgtat tagctgccct tgtacaaaga tgggtatcaa
     6421 tcaaattctt accagttgta tcaactgtaa aattagataa aggtgcttac atcgaatggg
     6481 ataaattgcc ttcaggtggt gaaggaatca agagtgcatt tgaacaagtt aataatggct
     6541 tagccctttc tcctgaaaag gtaacaacat tacaagacaa cttagaccaa ttgattcctg
     6601 gtttagctgc attaggatta acattgttat gtatgtggtt gcttaagaaa aaggtttctc
     6661 caatcgttat catccttggt ttattcgtag tcggtgttgt tggacacgtc atcggacttt
     6721 tataatccat aaaaatatag ctcgggcgtt gtcccgagct ttttttatat agtatactgt
     6781 tcataaacaa atatctggag ggagaaaatg gttcaatcaa tcaatacaaa agtagacttg
     6841 gtaattgatg ctacttcgtt tacgggtctg acagattacg ggcaaatcat gataggtgat
     6901 aatggttttg agttttacca tgcgcgagat agacgcaaat atatccaaat tccatgggaa
     6961 gaagtggatt atgtactagc atcagtcatg ctaaagggaa aatggattcc tcgatatgcc
     7021 attcaaacga aaaaaaatgg tacatacaca ttttcttcca aagaacctaa aaaagtgctt
     7081 cgtgcgatca gagaatatgt agatgaagat agaatggtac aatcattgag tttctttgat
     7141 gtagtgaaac gtggtattcg tagtatgttt aaacgcaagt aaaaaataaa gaaaacttct
     7201 aagaggaggt tttctttatt tttttacttt gcagaagaaa atatgaaata gcaaaaccaa
     7261 ttatttgtcc cctttaaatc ccatatgcta aaattgatta gcaaagaagg aggttatatt
     7321 atgagttggt tatggacatt gattgttgga gccgtgatcg gagcaattgc aggtgcgatc
     7381 accagtaaag gaaattcgat gggctgtgta acgaatatca ttgctggact agtcggttca
     7441 agtattggac aagcgatttt cggcgaatgg ggaccaaaag ctgcaggtat ggcacttatt
     7501 ccatctattt taggcgcagt gattttggta gcagttgtct catttttctt tggaaaacga
     7561 tcataagttt ttacaaaata gtaaactaaa aggagttgca gcgagactgt gactcctttt
     7621 tggctttatt tatttaaaat aaaaagaagt tttccggaaa tttttattta actgtcgtgt
     7681 acgaagaaaa gtttgctata atggaaaaaa gcgtgcaaag aaagagggag tttcattatg
     7741 atgctacgtg tagaaaaatt gcgcaaaaaa atgcaagaag aaaatttgga ttcatttttg
     7801 gttaccagtc cgtacaatct tcgttactta acgaacttta caggtacgac aggattagct
     7861 gttattactt tggaaaaagc attttttatt actgattttc gttataccga gcaggcggca
     7921 gcgcaggctc aagggtttga aattattaaa aatgtcggac ctatttttga tgaggtagca
     7981 aacttagtac gcaaagaaga actgcactca ttagcttttg aggaaacaac agtctcattt
     8041 ttagaatatt cggttttaga agaaatcatc gatgcggaat tagtacctgt ttcacagatg
     8101 atcgaagaac tcagagaagt gaaagatgaa gaagaaatcg ctattatcga aaaagcatgt
     8161 catattgcgg atatggcata tgatcacatc ctgaaaatga tccaaccggg catgactgag
     8221 attgaagtcg caaatcaact agacttttat atgcgttctc ttggcgcttc aggtgtttct
     8281 tttgatacga tcgttgctag cggattgcgt tcggctatgc cgcatggtgt agcaagcaaa
     8341 aaaatcatcg aacaaggtga cttgatcaca ttggactttg gttgctatta cgaagggtac
     8401 gtttccgata tgacacgtac attcgctatt ggtgatcctg gggaaaaatt aaaagaaatt
     8461 tatcaaatag tcttagatgc tcaattagca gttattgatg ctgcaaaacc aggaatgact
     8521 ggtgtccaat tagatgcagt tgctagagat tatatttcaa aacatggtta cggggaagca
     8581 tttggacatt ctacaggaca tgggatcggt ttagagatcc acgaaggacc aaacgtttct
     8641 tctcgtgcag aaaagcaatt tgtaccagga aatgtgatca ctgatgaacc agggatctac
     8701 ttaccaggaa tcggtggagt acgtattgag gatgacttgt tgatcacaga agatggaaat
     8761 cgtgtgttga ctcgttcacc aaaagaattg atcatcttat agtttcatca atagaagaag
     8821 taagcgtaaa aatcagtgtt cacagacttt gttatagaaa atcactcgat ttaatgatac
     8881 actatagaag aacttttaag ctgtaagaga taataaagtt gggtgttttc tccaattcat
     8941 agcagtttgc agctgatcgg cggcagtttt cttaccacgt gatcactatg ccgcatcata
     9001 gagaattcgg atgtatctcg tgcttaggca aagggaggaa taaataaatg gcagatgaaa
     9061 aaaatttgat tttaaacgca aaccaagatt taggagagat cgtgatcgct cctgaagtca
     9121 tcgaagtaat tatcgggatt gcagcttcta aagtagaagg cgtatacgga atgcgcggaa
     9181 cttttgccag caatgtcact gaattattag gacgtgcagc tcacggaaaa ggtgtttact
     9241 tagcaaacga ggaagatggc ttgaaagtag atctttactg ttatctagaa tatggtgttt
     9301 cagttcctaa agtagcaatg gaaatgcagg aacgggtcag ccagcaagtc cttttcatga
     9361 cggatatcga tttatctgaa gtcaatatcc atgtagtagc tgttgttcct gaaaaattag
     9421 aacaaccaac aatcgaagaa ctttttgaag acgaagagga agagaatgaa taaagaatta
     9481 tcaagacacg agattcggga aatggcattg caggctttat ttccattaga cttcaatgca
     9541 gacctaacaa aagaagatgc gattttcaac gcaatcgaat tagaccaccg cgacatgatc
     9601 aacgaagatg aatcagagtt tgttcctgtt tatcttgata cgctagttgg cggtgtctgt
     9661 gcaaaaaaag atgaattgga taaagtgatt gaaaaacatt taaaaaacaa ttggcacatc
     9721 aatcggatct caaaaatgga tttggtgatc ttgcgtatcg cgatttttga aatgacttat
     9781 gtgacagatg taccagcggc tgttgcttta aatgaagcaa tcgagttggc aaaaacattt
     9841 agtgatgacc gttcacgtaa attcgtcaac ggtgttttat ccaatgtatt gaaagaatta
     9901 gaagctgggg cgtaagtcct agcttttttc tatgaatcat cataaacctg ttataaatcg
     9961 ggaaaattct atggtagaat gaaaacacaa aaaatatctg ggagtggtta gatggcagaa
    10021 ttgattaacg gaaaagaatt agctgaaaaa atgcaggcag agattgctga aaaaatccaa
    10081 aaattgaaag ataatggtat ccatcccgga ttagtcgttt tattggtagg ggaaaatcca
    10141 gccagccaaa tctatgtaag aaataaagaa cgtgtagcaa aagaaatcgg aatccattca
    10201 ttggtagagc gttatcctga gacgatttct gaagacgaac tacttgcaga aattgaaaaa
    10261 tacaatcaag atcctagttt tcatggtata ttggtccaat taccattgcc aaagcatata
    10321 gatgaagaaa agatcctgtt agctatccgc cctgaaaaag acgtagacgg ttttcatccg
    10381 atgaatttag gcagactcct tgcgggtaaa ccggacaaga ttccttgtac tccatacggc
    10441 atcatgaaaa tgtttgaagc ttattctatc gatccggcgg gtaaacgagc agtagttatc
    10501 ggacgaagca atatcgtcgg taaaccgatg gctcagctac tcttgatggc agatgcaact
    10561 gttactgttg ctcattctaa aaccgaaaat ctggctgaac tggcacaaga agcagatatt
    10621 ttagtcgtag caataggacg tggacatttt gtcacaaaag aattcgtaaa accaggtgct
    10681 gtagtgatag atgtagggat gaatcgtgat gctaacggta agctgatcgg tgatgtgaaa
    10741 tttgatgaag tggagcctat tgcaggctgg atcactcctg tgccaaaggg tgtagggcca
    10801 atgactatca cgatgctgat gtatcaaacc gtaaaatctg ccgaagcttt tggagcaggt
    10861 gaatagatgg cacaagaata tttaactgtc actacattaa cgaagtattt gaaaagaaaa
    10921 tttgatgccg atccttattt agaacgcgta tatttaacag gcgaaatatc gaatttccgt
    10981 ttacgtgcca atgcccatca atatttcagc ttaaaagatg accatgcaaa aatatctgct
    11041 attatgttca aaggagcatt ccaaaaatta cgattccagc caaaagaagg aatgaaagtc
    11101 cttgtcgttg ggcgtatttc attatatgaa gcgggaggtt cttatcaaat ctatgtagag
    11161 cacatggagc ctgatggaat aggtgcttta tatcaagaat tggaagaacg aaaagaaaag
    11221 ctgatgaagg aaggcctttt tcaagggcct aaaaaaatgc tgccacgttt cccaaagcga
    11281 atcgcggtcc ttaccagtcc aagcggagcg gttatccgcg atatcatcac gacggtgaaa
    11341 agaagatatc caattgtcca attggttttg ttcccaacag ttgtacaagg aaaccaagca
    11401 gcggacaatg ttgtcaggaa tatccagaga gtagaagaga tgggcaattt cgatacaatg
    11461 atcatcggtc gtgggggtgg ttcgattgag gatttatggc cgtttaatga agagcgggtt
    11521 gctcgggcga tttatcaagc taatacgccg gtgatttcat ctgtaggaca tgaaacagat
    11581 accacgatcg ctgatttagt agcagatgtt cgggctgcca ctccaacagc agctgcagaa
    11641 ttagctgttc ctgttttgtc agaagagttg atgcgcattc aagaacggca agctagattg
    11701 cagcaggcgt ttgtacgcca gatccagcgc aaacaagaac ggttcgagcg tgctcgacgt
    11761 tcctatgtat ttcggcagcc tgaaagattg tatgaaggtc agaccatcaa attagaccag
    11821 ttgaaacagc gattatatca agctacacag caaatttatc atgcgaaaga aaaacaaacg
    11881 atcgcattaa gccaccaatt ggaacaagtg gctccgcttt atcgagttaa agcagctcgc
    11941 caagaaactg cttatctaga aaaacgctta gaagagaaaa tccaacaata tatgaaacaa
    12001 cagcagcagc gttttgctca agctgttcaa tctcttgatt tgttgagtcc attgaaaatc
    12061 atgggaagag gctacagcta tacgacgtta aatgatcaag tagtaaaaag tgtcaccgag
    12121 attcatcaag gggatttgct gacgatccat tatcaagatg gaatcgttaa aggacaagta
    12181 caagagatag acaaaggaga ataaaaatat ggaaaatcca acttttgaag agtcactgca
    12241 agaattagaa aaaattgtca tgcagttaga acaaggagac gttccattag aatcagctct
    12301 agattcgttt aaacgaggaa tggaattaag caaacattgc caagatacat tagctaaagc
    12361 agaagagacc ttgacgaaaa tgatgacaga atcaaatgaa gaagttgatt ttgacggaaa
    12421 cgaggaaagc tgagatgaga ttaactgact tttcagctat tcatctacct gctgtagaaa
    12481 aagaaatctt gtctttttta gatgagcata caacggatag aggactctat gatgcgatga
    12541 gttattcagt gaaagcaggc gggaaaagaa tacgtccctt attactttta acggccgttg
    12601 cttcctttga tgagcctatt gatgttcccg tctatcaagt agcagctgct ttagaaatgg
    12661 tgcatacgta ttccttgatc cacgatgatt tgcctgcgat ggacaatgat gatcttcgta
    12721 gaggaaaacc taccaatcat aaagtattcg gcgaagcatt agctatattg gccggagatg
    12781 gtttgcttac aggagcattc cagctaatca gtatggcaca cttaggtaat tctcctaagc
    12841 ttctgctgct tcagcaatta gctgtttgtg cgggatcaca aggtatggtt gctgggcaag
    12901 ctgcagatat cgagggcgaa tcgaaaaagc tttctttaga agaattagca tttattcatg
    12961 aaagaaagac agggcatttg attcgttatg ccttgctggc tggtggcata ttagcgaagc
    13021 aacctgaaga aatcttattg ctacttcaac gattagccga acatttaggt ttagcttttc
    13081 agataagaga tgatctactc gatgtgattg gtacaacgaa aacattaggg aaaacagctg
    13141 gtaaagatga acgtatggaa aaaaatactt acccgcgttt attaggccta gaaaagacac
    13201 gtgaggcgtt ggagattgag ctgttatccg ccaacaagat catagacaaa ttagaagagg
    13261 acgttttttc ttttgatggc gggctgatgc gccagatgat caagcaattt gatgtggaga
    13321 aatgagggaa agaatggaaa aagaacgcgt agatgtatta gcggtcaaac aaggattatt
    13381 tgaaacaaga gaacaagcca aacgttcagt gatggctggt ttgatttaca acgaaaaaaa
    13441 cgagcggttt gataaaccgg gagaaaaaat tccagtgagt agtgaattaa gagtcaaagg
    13501 taaaaaactt ccttatgttt ctcgaggggg attaaaatta gaaaaagcac tcaaagcatt
    13561 tgatctatct gttgaaggaa aaacattgtt agatattggt gcatccactg gcggatttac
    13621 tgatgcagct ttgcaaaatg gcgcaaaaat gagttatgct ttagacgttg gctacaatca
    13681 gctagcttgg aaaataagac aagatcctag agtcgtcgta atggaaagag tgaattttcg
    13741 ttatgcaaaa cccgaagact ttaccttagg aattccagaa gttgctgtta tcgatgtttc
    13801 ttttatttca ctaaaactga tgctgcctcc attacatgct attttaaaag aagagggaga
    13861 agtgattgct ttaatcaaac cccaattcga agcaggcaga gaagctgtag ggaaaaacgg
    13921 aattgttcgt gaccctcaga cccatcaaaa agttttagaa gacattttgt catttgcggc
    13981 acaaggtgga tatgatgtgc tggaattaag ttattctccg atcacggggg gagaaggaaa
    14041 tatcgagttc ttggctcact tgaggaaagt acccgaaagc ggaacaatca attcagctat
    14101 taatatggca gaagtggttt caaatgcaca cgaacagttt gaccataaat aaattgtaac
    14161 tgtgaaaatc aagtgagaag tatgcggatt cttctttatt ataccaagga aataagctat
    14221 cattgattaa gaagaatatg ctaaggagcg aagacgtaat gagaaaaaaa gatcggcatc
    14281 gtttgattac tcgattgttg agtgagcaag atatccgaaa gcaggaagaa tttgttgaaa
    14341 tcctgaaaag caaaggaata tctgttactc aagctacgat ttccagagat ataaaggaac
    14401 tgaaactgat caaggtaccg gcttcagatg gcggctaccg ttatagcata ccagctgaaa
    14461 caaacgaaga tgtaaatact aaattggaaa aactattaaa agacgctttc gtggcagttg
    14521 accaaatgga aaaatttgtt attttgaaaa cattgccggg aaatgcttcg gcagcagcaa
    14581 atttgattga taaacgttac aagaaagaat tattttcgat tatcaatgat gacgataatg
    14641 ttttgatgat tacacgaact gaagaccagg cagttttatt gaagaaagac ttcctgcatt
    14701 acctttaagt tgaggagcga atgtgatgct acaagaaatc agtattacta actttgcgat
    14761 tattccggaa ttgcggcttt cttttcacga aggaatgacc gcgctgaccg gagagactgg
    14821 tgcgggtaaa tccattatta tcgatgcttt aggtctgtta gcaggaggaa gaggttcaag
    14881 cgattatata cgtcaaggag cagaaaaatg tgtgcttgaa gggttgtttg aactaccaaa
    14941 acaagaagga ttctctgaac tgatggttga attagggatc gaaacagatg aggacaatct
    15001 gattgttcga cgggatatgt ccttaactgg aaaaaatgtt tgtcgagtga atggtcatat
    15061 tatcacatta gctaatctga gaagaatcgg cagttattta gtagatatcc aaggacaaaa
    15121 cgaacatcag gaactgctcc agcctgaatc acatcttgct ttattggatc gttttggaga
    15181 tgtagctttc caacagaaga aaaagagtta tcagcaagaa tatatctctt atcgtgagct
    15241 ggaaaaaagg gtacgaaaag tgcagcaaaa tgaaaaatcc tatgttcaga gaatagatat
    15301 gctccatttc cagcaagaag aaatagctgc tgctgatttg caagtcggag aagaagagaa
    15361 attaaaagaa gaaagagaaa aacttagcaa ttatcaaaaa attgctgatg gattagctgc
    15421 aggttacgga gcactgacga ataatgaaca aaacagtgta gatggtgttg gcttggccgt
    15481 ttcagaactg caagggatcg cccatctaga tgtggagtat gaagcaattt atgaaaatat
    15541 ccaaagtgct tactatttgc tgcaagatgc aatcggcgat atgagtcgtc agattgattt
    15601 attggagtta gatgagagtc gtttagaaga agttacgcaa cgtttagaat taatccgaca
    15661 gttgaaacgt aaatacggcg aatccattga gtcaatattg gcttactatg acgaaatcac
    15721 cgaagagcta gcttcttctg atttttcaga aggtcaattg gacaaaatga aagaggaact
    15781 agagcaaaaa gagcttctac ttcagcaaca agccgcagat cttcatgaag cgcgtaaaaa
    15841 aatcgcaaaa gaattggaaa aatccattct gcatgaattg aaaagtctgt atatggaaaa
    15901 cactgagttt gaggtacgtt tcttaaaaga agaaaataga caattgaatc atgatggatt
    15961 tgaccaaatc gaattttaca ttacgaccaa tccaggagag ccactgaagc ctttggtgaa
    16021 agtcgcttct ggtggcgaac tgtctcggat gttgcttgct ttgaaaacta ttttttcttc
    16081 tgagcaaggt gtgacaagta ttatttttga tgaagtggat acaggtgtga gcggaagagt
    16141 tgcacaggcc atcgcagata aaatttctca aatatcgaaa tactctcaag ttttgtgcat
    16201 cactcatctg cctcaagttg ctgcagtcgc cgactatcaa tattatattg tgaaagcagt
    16261 gattgatgga cgtacgcaaa cttctgtttc agagttgaaa acaaaagaaa gagaagaaga
    16321 aattgcacgt atgctggctg gaagtgagat tacaaaactc acactcgaac atgcaaaaga
    16381 actattgaaa ctcgcaaaaa ggacctgagc cacctcgcag tggttcaggt ccttttcagc
    16441 agctgatagc tatattttat ttttacatga cactcattac agcagtcaat acaacagatc
    16501 caatcgttaa aatcagcatt gtccaaatga caaattttgt tactttagca aaagtacttg
    16561 tttgtttttt ttcacgcatt gttttcaacc tcgtcattaa ttagttgatt caagtgtaca
    16621 atcttttttc catttccaca agagggcttt tttataaaaa cttccctttt tttaaataat
    16681 aggtagttac gatacaaata aataatgtta atagaactag ccatataaag gcatcatccc
    16741 tttcagcaat aggtaactta atgttcattc catagatact gccgacgatt gtcggtatag
    16801 ttaaaataat cgttaaagaa gttaaaattt tcataatatt attcagatta ttcgatacga
    16861 ttgctgaaaa agtctgattc atttgttcta ctagttttaa ttgaatgcga gaagtagtca
    16921 ttgcctgctc tgtttccacc aatacatcac gtaaatgatt tttcaaagca tgattttctt
    16981 ggaaaagttt attttgcgct agttctttca atgcatctaa attagcagaa gtcgcttctc
    17041 tgaaataaac gaggcttttt tggatatcca tgatttgata aagttgtttg ttttcagtgg
    17101 atacttgaag tttggcttcc aaagtatcgc attgagattg aagcgtagct aaataactgt
    17161 tgtaagagag tgtgacctgc caaatgaatt gaaagaagat attgagatta ggcgaaatat
    17221 cactttttgg aaaggtctgg ctaaagactt tctttaaaaa cagtggttca tgattcgtaa
    17281 ttgtgataag cttctttttg ggcgtcaaaa taatagagag cgggtatgta tccacttgaa
    17341 aataaccgct aggacttgtt ttagcaaaag gatattgtaa caataataac gctggctttg
    17401 tcaactttga ttgattgaat tcttctgtac gggaattttc tgcatcgtcc aatatggaag
    17461 tgatgtaatc tgacggaatt tcaaattgat gtgtcagctg atgaatctct tcttgattag
    17521 gacgttctac acaataccag atcgtttggt cagtttcctt tccggtatta cgcagtttct
    17581 cattatctaa tgtaaaatat ttgatcatga ttttcctcct gttgcctgtt tcttttatta
    17641 taacggatag ggaattggaa tacatggaat gtgtttgtaa gatatagaat ataactgcat
    17701 aaatttaaat aaaatgaaac agttgtgtaa agtatataca gtatacttga agcaacgata
    17761 aaaaaggagt ttacgttcat gggcacattc acaccactta tcttgttttg gtatatttac
    17821 ccggtaatcg ttttgtttgg ttgccaattt cttgtaaaat tattttcgtt aaatcgtcgt
    17881 tttaaaataa aagcccctga tttggcgatt ccttttttgt ggggcggtat gcatgcattg
    17941 tctagaaata cagggacaat ttctatctta ccgtttttct ttatttctgt tttgctaatg
    18001 ggaatttgta ttgctgtttt ccaagcatat tattatgaag aaattattta tccgcgttat
    18061 ttcaagatga cttggcgttt ggtttttctg ttgacaatcg tcttgtacgc tgtcttgatc
    18121 attgtgaaca tactttctta cctatgaaaa aaatagaaaa gctgtaaaaa gtcttttaaa
    18181 aggctttttg cagcttgatt tttaaaaaaa tgtttatgaa taaaaaaagt tgttcccgga
    18241 tttcccagaa aaggtggtag aaagtggggg attgtggtag actaatttta gttagtggag
    18301 gaatgggggg gctttcaatg ttgatgggtg aattccaaca taatattgat gcaaaaggac
    18361 gtttaatcgt gccctcaaaa cttcgtgaag aacttggcga aaagtttgtt ctgacacgcg
    18421 gattggatgg ctgtcttttc ggctatccga tgagcgaatg ggaaaatctg gaagctaaac
    18481 tgaacgaaat gccgttggct aaaaaagacg cacgtacttt tgtgcgattc ttctattcgg
    18541 ctgccactga atgcgaactt gataaacaag gacgaatcaa tatacccagc acgttaagaa
    18601 attatgcagc tttgacaaaa ggttgcgtag tcatcggtgt atctaaccga attgaaattt
    18661 gggatgagac acgatggcaa gatttttctg cagcagcaga agagaacttt gacgaaattg
    18721 ctgaaagtat gattgatttc ggactataag aataggaaga ggctgactaa tgactgaaac
    18781 atttcaacac tatacagtca tgttgaaaga aacggtagat ggattgaaca tcaaaccgga
    18841 tggcgtttat gtagactgta cactcggcgg tgccggacat agtgaatatt tattaagcca
    18901 actaagttct aaagggcatc tgtatgcgtt tgaccaagat caaaaagcaa tcgatcacgc
    18961 caagctgcgt ttagcttctt atgtcgaaca aggtatggtc acatttatca aagcgaactt
    19021 cagagaatta gaagaacgct tgagtgagca tgtagataag gtagacggca ttttgtatga
    19081 tctaggggtt tcctctcctc agctagatga agcagaacgt ggatttagtt atcatcaaga
    19141 tgcaccgttg gatatgcgca tggatcagtc agctccttta tccgcttatc acgtaattaa
    19201 tgaatattcc taccatgaat tagtaaagat tttcttccgc tatggcgagg agaaattttc
    19261 caaacaaatt gctcgtgaaa tcgaacgagt acgaaaaaca aaaccaatcc aaacaactgg
    19321 tgagcttgtc gaaatcatta aacaagtcat cccagctccc gcaagaagaa aaggcgggca
    19381 tcctgcaaaa agaatttttc aagctgtgcg gattgcagta aatgacgaac tcggtgccga
    19441 agaggcctct ttagaacagg caatccggtt attgaaagtc aatggaagaa tcagcgtaat
    19501 cacattccat tcattggaag acagaattgt caaaagtatg tttaaagaat atagtacggt
    19561 acaagatcta ccaccgggac ttcctgtcat acctgacgaa ttccaaccag aactgaaagt
    19621 cattactcgt aaaccaatcc ttccttcaga ggaagagcta acagaaaaca atcgatcacg
    19681 cagtgcaaag ttacgtattg cagaaaaaat aagaatgaaa gaggagtaga atgatggcag
    19741 aattaaagaa aatgcaagat tacgaatatg atttacctga attggtggat cagccggaac
    19801 aacaaatgcc tgattcttct tcgaatcaag aaatcattct tccacaatca ccggcaaaac
    19861 gattaaagca gatttctgct ttggaaaaaa ttgctgtggc aagcgtggcg attgctattg
    19921 ttgctttatg tgttttaaca gttatgctgc gcacaaatat cagcggagct gaaaaagaaa
    19981 tcacgtcaat acaaacagaa atcaatgata aaaagcaaga aaaaacgagt ttagaacaag
    20041 aaaaaaacga actttctcgt actgaacgga ttaaacaaat cgcagaagaa aaaggattgt
    20101 ctattaatga cgacaattta aggaaagtga agtaaatgag tcttaaaaat aaaattcggc
    20161 ggtttatgga aaagaaaaat ctaaatccga taaacaatcg caaaaaagta ggtatcattt
    20221 tatttgctac gagtattgga ttgttctttt tatttgccgt ccgtttctcg tatatcgtta
    20281 ttggaggtca tgttgctggt acctcattag ctgaaaaaac aaaacagttg taccaaggaa
    20341 gtgaagtagt aaaagcaaaa agaggaacga tttatgatcg taacggtgtg gcgctcgcag
    20401 aagatgcctc ctcttattca attaaagcga tactctcaaa aacatatacc tctggggata
    20461 aaaaactgta tgttgaagaa aagaattttg ataaaatagc agaaatcctg cataagaatc
    20521 tttctataga caaaaaagat gcactgaata ttttagagga cggcgcaaaa aaagagctgt
    20581 atcaagttga atttggtagc tatgggaaaa atatctccca agaaaccaag caaaacatcg
    20641 aagcggacat gaaaaaagaa ggtgtcgctg gtctttattt tgtcgaccat caggctcgga
    20701 tgtatccaaa tggcgtcttt tcttctcatt ttattggata cgcagttcca gacaaagatg
    20761 agaatggctt agttggtaaa ctaggtttgg agtctgctta caatgatatc ttgagcggta
    20821 aagatggtaa gattatttat caaaaagata attttcaaaa tcctctgcca ggtacagtgg
    20881 cagaagaaga aaaagctgtc gacggacaag atatctacac gactttagac agcagactac
    20941 aaagttattt agaaacactg atggatcaag taaatgaaga atatcagcca gaagaattga
    21001 cagcagtcct gatgaaagca aaaaccggag aaatcttggc aatgggacaa cgacctactt
    21061 tcaatcctga aacaatggaa ggattgactg gaaaagatgc tatctggcgt aatttcttgg
    21121 tacaagatag ttatgaacca ggatcaacca tgaaagtttt cactactgca gctgctatcg
    21181 aagaaggaga attcaacgag aatgaaacct tccaatctgg aaaaatccaa gtagaagatg
    21241 ctacgatcaa tgaccatgac tttggtgaaa aaggtgtgct gaccatgcgt caagctcttt
    21301 catggtcaag taacgtcggg atggtcatac tggaacagcg attaggcgga cgatggtata
    21361 actatttaca aaaactggga tttggacaaa gtactcattc tggattagat gatgaagtaa
    21421 acggtgcttt acctacatta aatattgtcg accgagcaat gagtgcttat ggacaagcgg
    21481 taggtgtgac gaatttccaa atgatgaaag ctttcacttc tattgcgaat aacggtacaa
    21541 tgattcaacc tcgatatatc agcaaagtgg tggatcccca aactggagaa gagcgaacaa
    21601 ctcaaacaga agttctaggg caaccttttt caaaagaaac aacagaaaaa gtccgtgaat
    21661 atatgagaga tgttgtcgaa agcgaaaact acggtagtgc ttatggtgta tatagtgtac
    21721 ctggatacaa tgtatcggca aaaaccggaa cagcccaaat cgcttctgat acagggggat
    21781 atcaaacagg agatacagcc tacctgtatt cgattgtgga gatggttcct tctgaagatc
    21841 cagactatgt cttgtatcta acaatgaaac accctaagac atatgatcga atggcattgg
    21901 ctaaaatcgc aaatccattg atgaaacggg caatggattt taaagaaact gaagaagatt
    21961 cagatacaga aacaaaaaca gaaaaagtat ccgtagccga ttatcgtaat cttgaagcgg
    22021 acgttgcagc agctgatgct caaaaaagtg gactgcaacc tgtagtgatc ggtaatggta
    22081 aaaaagtaca aaaacaatct actgccaacg gtgatcagtt gatctctgga gaaaaactga
    22141 tcctatatac tggtggtgat aagctgatgc ctgacgtaac aggatggtca aaagcagata
    22201 tcatgaagct ggggaaaatc ctcggtattg aagttagttt tgatggagat ggttattgtg
    22261 tcaaacaaga acttgctcca tatgaaaaaa tcactgaaga caaacttagt tttactttag
    22321 aagaataaga agagaaatag gagagaaaag agcatggaat ggacacaagc attgattccc
    22381 attgtcagca gttgtgcaat gacaattgcc gcaatgccgc tatttattgg ttattttcaa
    22441 atgaaaaagc aaggtcaggc gattcgtgag gagggaccaa agtggcacaa tagcaaagcc
    22501 ggaactccta caatgggcgg cttagtgttt ctgatcggct ctattttgac aggaatttgg
    22561 gttggagctt ggcaaaaaca gctaactcct actcttttca tcttgctttt tgtattagcg
    22621 ttatacggag taatcggctt tcttgatgat tttataaaaa tattcaagaa aagaaacatg
    22681 ggactgaact cgaagcagaa attgattgga cagattctag ggggaatcat cttttatctt
    22741 gtttaccgtt ctgaaggtta tccaggtgta ttgaatttct tcggactaga tctaccttta
    22801 ggaatcattt atggtatttt cgctctcttc tggcttgttg gattttcaaa tgcagtaaat
    22861 ctgacagatg gcatcgatgg attagttgct ggcttaggaa gtatctcttt tgcagcttac
    22921 ggtctaattg cttggcatca gcatcagtat gatgtattaa tcatttgctt aagtgtttta
    22981 ggaggtttac tgggtttctt cgtctacaac agaaaacctg ccaagatttt tatgggagat
    23041 gtcggttcat tagcgttggg cggactttta gcggcaattt ctataatgct aaaccaagaa
    23101 tggacattgc ttttgattgg tttgatctat gttatggaaa cagcaagtgt gatgcttcaa
    23161 gttacttcct ttaagcttac aggaaaacga atttttaaaa tgtctccaat tcatcatcac
    23221 tttgaaatgt gcggatggtc ggagtggaag attgatacag ttttttggtt gatcagcatt
    23281 gtgacttcgt tgatcacatt atggatcgtt tggtaggaga tgacgggaaa tgaaaaaaat
    23341 atcaacatat gaaaataaga aagtgcttgt cttaggactc gcaaaaagcg gagtaagtgc
    23401 ggccaaatta ttacatgaat tgggcgcact tgtcaccgtt aatgatggaa aaccttttga
    23461 cgaaaatccg gaagcacaag agctgctttc tttagggata aaagtaataa caggtagtca
    23521 tccaatcgaa ttgttggatg aagaattttc attgatggtc aaaaatccag ggattcccta
    23581 cagtcatcct ttagtagcaa aagcccaaga aatgggtatt ccggtaatta cggaagttga
    23641 gctagcttac gaagtagcgg aatgcccaat tattgggatt acaggaacga acggaaaaac
    23701 aacgacaaca acgatgacag gactactact gaatgcagga gcagatcaag gaattgcacg
    23761 tttagcgggt aatattgggt atccagcaag tggtgtagcg caagaagcaa aatcagaaga
    23821 taaaattgtg atggaattgt ctagcttcca actcatggga atcacagatt tccgccctca
    23881 tatagcggtg attaccaata tctatgaagc acatattgat tatcatggta caagaaaaga
    23941 atatgtcaaa gctaaatgga accttcaaaa aaacatgaca gaaaaagatt atctgatcct
    24001 taactggaat cagtcagaac tacaagaatt agcgcaaaga acaaaagcac gcgtactgcc
    24061 tttctcgaca aaagaagtgt tggaagacgg tgtgtatgct gacgattact caatatacta
    24121 taaaaaagaa aaaataatgg aaatatctga acttggcgta ccaggtaagc ataatgtaga
    24181 aaatgcacta gctgctattt ctgtagcaaa attgtatggt atatcaaatg aagctatacg
    24241 agaaacgttg cattttttcc atggcgtacc acatcgtacg caatatgtag gagaaatcca
    24301 aggcagaaaa ttttataatg attcaaaagc aaccaatatt ttagcgacta aaatggctct
    24361 aagtggattt gaaacgtcta aggtcgtgtt attggctggc ggattagaca gaggaaatac
    24421 atttgatgaa ttaattcctt cattaaaagg aatcaaagca atggtcgtat ttggccaaac
    24481 aaaagaaaag ttgatggatg ctggaaaaaa agcaggcatc gagacaatag taacagccga
    24541 ttctgtagaa caagcagttc ctttagcatt agaaaacagt acagatggtg atgtagtttt
    24601 attatcacca gcgaatgcca gctgggatca atacccaaat tttgaaacta gaggaaacag
    24661 attcatggaa gctgtgaacc gattaaaata gaaaaagtag aagcgagcga taaaaaatga
    24721 aaattttggt tacaggcgga ggaacagggg gacatattta tccagctctt gcctttgtca
    24781 attatgtaaa gactcaagaa ccgaatgctg aattcatgta tgtgggagca aaacgaggtc
    24841 tagaaaacaa aatcgtccct gatacaggaa tgcctttcca taccttggag attcaaggat
    24901 ttaaacgaaa aatttccatg cataacatca agacggtccg attgtttctt aagagtatcc
    24961 gtcaagcaaa aaaaatcctc agtgattttc aaccagatat cgttatcggt actggaggat
    25021 atgtttccgg agcggtagtg tacgctgcag ccaaaatggg tattccaaca gttatccatg
    25081 aacaaaacag tgtaccaggt gttaccaata aatttttaag ccgatatgtg gatcggatcg
    25141 ctctttcatt taaagatgcg gcttcctttt ttcctgaaaa caaagcagtt cttgtaggta
    25201 atcctcgagc acaagaagta gcagatacta aaaaatcaga tattttgaaa acatttgatt
    25261 tggatccaga aaagaaaaca gtcttgattt ttggcggtag tcaaggagca cttaaaatca
    25321 atcaagcagt atcagttttt ttaagtgaat atattccttc ttcttaccaa gttttgtatg
    25381 cttcaggaga tagatattat gaagagatcc taaataaaat aaatcctgaa atacaaaata
    25441 ttagtgtcca gccttatatc aaaaatatgg cagaggtcat ggcttccagt gatctgctgg
    25501 tggggcgtgc tggtgcaact tcgatcgcag aattcacagc tctggggtta ccggcagtgt
    25561 tggttcccag cccatatgtt acgaatgatc atcagactaa aaatgcaatg agtcttgttc
    25621 acgcaggagc agcaaaaatg attgcagata atgaactaac aggtgaatca ctaagtcaga
    25681 cagtcaacga aatcatgggt gatgaagaat tgcaaaagca aatgtgccga gcttctaaag
    25741 aacaaggaat ccctgatgct tcaaaacgtc tttatgactt agtaaaacaa ataatcaaaa
    25801 aataaaggcg gtggtcttag tgagtaagaa aaaagaacca aaaaaattgt ctcatccgtc
    25861 ttctgatgaa aacaatttga ctccttggca aaaggctaac cgaaaatatc tggcagaaca
    25921 agagatgaaa aaccaagagc caaaaaaaga agacataaca ttagatacac ccctttcaga
    25981 ttctgaagaa gaaaaaacgg ttcaagagga acagcaagaa gaaagccagt ccgagaaaaa
    26041 aatcgaattt tttgaagaga tcaagcaaaa gaaaaacggt ggaccatata acggttcttt
    26101 tttgaaccgg ctgcccaatt taaaaagtca acggcacaaa gtactatttc gtcggttagc
    26161 tttgatcatc actgtattgg gtataccgct gatttttttg atctattatg tttctcctta
    26221 tagcaaatta caagcagttg cagtatcagg caataagaca gtcaacagcc aagaaatcat
    26281 ctctgataca aaattgtcat taggagaaaa tgtttgggga cagtattttc atcgatctac
    26341 ttatatcgat cgccttaaaa aagcacagcc aagaatcgaa acagcaaata tacatttcaa
    26401 agggatgaat gaattcgatt tggatgtaac agaatataaa gagattgctt tgatcgcaaa
    26461 aaacaatcaa tactacccag tgattgaaaa tggaacagta ttagatgaaa aagtagcaaa
    26521 tcctacaaaa aatctcccta tcttggaaga gttcaaagac tctgcaaaaa tcaaagaatt
    26581 aacaaagcaa tacaatcagt tatcatcaga attacaaaaa gcaatttctg aaatcaagta
    26641 cacgccaaga gcaagcaata aaaatctgat ccaattgaat atgaatgacg gcaatcaagt
    26701 tattgtaaat atcaataatc ttgcgaacca aatgaaatat tattcgcaag tagccaaaga
    26761 tatggatgaa aaaggtgtga tcgacatgga agttggtatc ttctcgcatc cttacggtag
    26821 cactcaagaa acggaagaat cgggccaatc ggaagaaaca actgaaagtg aagaaaatgc
    26881 ggatcaaaca aacgaatcaa gtgaagaggc agaaacgcaa aaagcacaaa cacctggatc
    26941 gtctagcaca aacggatcat ctgattcaaa tgattcaagt gaaacaagtc aaatagaaga
    27001 taatccaagt acaactccgt caagtttaaa tgaaaattga taaaacaact ttaaaaagta
    27061 agaatgtact ttctaaaaac cagtaattta tggtagaatt ggaagcagtg aatatatcta
    27121 ttaataagta tattttaaaa cggacgctag ttgttcgctt gtatatggaa tagtaagtag
    27181 gagggaatcc cattcatggc aaaaacagga atgtatgtag gccttgatat tggaacgaca
    27241 tctgttaaag ttgtcgtggc tgaatatatc gacagccaaa tgaatattat tggagtagga
    27301 aacgcaaaat cagaagggat taaccgaggc attatcgttg atatcgataa aacggtccaa
    27361 gcgatacaac gagcagtacg acaagcagaa gaaaaagcag gtatccagat caaaggcgta
    27421 agtgtcggtt tgccagcaaa catgcttgaa gtagaaaatt gccagggaat gattgcagtt
    27481 aacggagatt caaaggaaat caccgatgaa gatgtcagaa atgtggcttc agctgccctt
    27541 gttcgttcaa tacctcctga acgtcaaatc gtgtcaatat tgccacaaga ttttactgtc
    27601 gatgggttcg agggaatcaa agatcctcgt ggaatgatcg gcgtaagatt agaaatgtac
    27661 ggtctgttgt ttacaggacc taaaacgatc atccataaca tacgtaaatg cgtggaaaat
    27721 gccggattaa tcgtcaacga aatggtgatt actcctttag cgctgactga atcaattctt
    27781 tctgacggag aaaaagattt tggtacgatc gtcattgata tgggtggcgg ccaaacaaca
    27841 acggctgtta tgcatgataa gcaattgaag tttaccaatc ttgaccaaga aggtggcgaa
    27901 tttgtcacta aagatatctc tattgtatta aatacgtcat ttaacaatgc agaagcgttg
    27961 aaaataaact acggggatgc atacccagaa cggacatcac cagatgaaga atttccagta
    28021 gatgtgattg gtcagtcaga accagtgaaa gtcgatgaac gctacttgtc agaaattatt
    28081 tcagctcgaa tggaacagat tttcaacaaa gcaaaagatg cattggacca aatcgaagca
    28141 ttagagttgc caggtggcgt cgtattgaca ggcggagctg ctagtcttcc tggtgttgtg
    28201 gacttggcac aagaaatctt cggcgtaaat gtaaaattgt atgttccaaa tcacatgggg
    28261 ctgagaaacc cggtatttac aaatgtaata agtatcgtgg attattcagc aaacttgagt
    28321 gaagtgtatc aattggcaaa aattgctgtt acgggtgaaa cctcagcagc tcgtcaaatg
    28381 gtagttgaac aagaaacaac aaacacatat gagagctatg aagcacctga agaaacaatc
    28441 tacgatgagc cggaaccaaa agagtccgga gaaaatgtaa aaaataaaat caagggtttc
    28501 tttacaaata tttttgatta attcatcctg ggaggaataa gatatggaat tctcaattga
    28561 taataatatc aatgacggcg cagtaatcaa agtcatcgga gtcggtggtg gcggtggaaa
    28621 tgctgtaaac cgaatgattg aagaaaacgt taaaggtgtt gaattcatta cagccaacac
    28681 agacgtgcaa gcattaaaaa attcaaaagc tgaaacagtt atccaattag gccccaaata
    28741 tactcgtggt ttaggtgctg gttctcagcc agaagttgga caaaaagcgg cagaagaaag
    28801 tgaacaatcc ttacgcgaag ctttagacgg tgcagatatg attttcatca ctgcaggaat
    28861 gggtggagga accggtacag gtgctgcacc aatcgttgca ggtatcgcga aagaattggg
    28921 cgcattgact gttggtgtcg tgacacgtcc attcactttt gaaggaccga aacgtggccg
    28981 ttttgctgca gaaggtatcg ctcgtttgaa agaaaatgtg gatacattat taattatctc
    29041 aaataaccgt ttattagaag ttgtagataa aaagacaccg atgcttgaag ctttccgtga
    29101 agcagataat gttttacgac aaggtgtaca aggtatctct gatttgatca cagcgccagg
    29161 ttacgttaac cttgactttg ctgacgtgaa aacagtgatg gaaaaccaag gtacagcatt
    29221 gatggggatc ggtgtggcta gtggagaaga tcgcgtagta gaagcaacga aaaaagcaat
    29281 ctcctctcca ttgcttgaaa catctattga tggagctgaa caagtacttc ttaacatcac
    29341 aggcggtttg gatatgacat tgttcgaagc acaagatgct tcagatatcg tagcaaatgc
    29401 agcaactggc gatgtaaata tcattctagg tacatctatc aatgaagaaa tgggcgatga
    29461 aatccgtgtg acggtcatcg caacaggtat cgatgaatca aaaaaggaac gcaagtctag
    29521 ccgaccagct agacaagcac aaatgcaatc acctgctcaa aagactgtat tagatatgga
    29581 tcaagctaaa ccaacttctt cagaagaaga aaacagtttt ggcgattggg atatcagacg
    29641 tgaacaaaat gttcgtccta gagttgatga ttccaatttt gacaatatcg aaaaaaaaga
    29701 atttgataca ttcaaccgcg aagaaacaaa atctcatggc gatgatgaat taaatacgcc
    29761 accgtttttc cgtcgtaaaa aataaaggag aggaagagca catgattgct gacaacttgc
    29821 agaaaatcaa gcaagaaatt caggattcgt gtgctcttgt tcatcgtgat ccgaaagaag
    29881 ttacattagt agctgtaaca aaatctgttg aatccgctca agctgaagaa ttggttagag
    29941 ctggcgttat gaattgtgca gaaaaccgag tagataaatt attagaaaag aaacaagatt
    30001 tatttgattt tcctgaaata aagtggcatt taattggtaa tttacagcgc agaaaggtaa
    30061 aattgattgt aaatgaaatt gattactttc atgcgttgga cagtttaaga ttagcagaag
    30121 aaatccagaa gcggttagag aaagaattat cctgttttat tgaagtaaat gtttctggtg
    30181 aggaatcaaa acatggaatt tcaccagatg agcttttacc gtttgtggaa tctttagctg
    30241 cctgcacaaa aatcaaggtt gttgggttga tgactatggc gcctaaagaa gcttctgatg
    30301 agcaaatcca taaagtgttt ggtacgctga aagaattgcg tgatcttgtt caagcaaaag
    30361 gttatgccca tgcaccatgt agtgaattaa gtatggggat gagtcaagac tttcaaattg
    30421 cgattgaaga aggtgcaaca tttatccgtg taggaacagc gctattcaaa gacgaataaa
    30481 ggaggaacaa aaatgccgct tttaaacaga ggagcaattg ctaatttttt cggattagct
    30541 gatgaggaag agtacgaata ccaagattat cctgaaacaa caaaaaaggc tgtacagcca
    30601 actaaaaaaa atacaacaca gaatcaatca actcattctg tatctgctgc gaatactcat
    30661 gaaaaacaaa aaacggcgac ttcacgtcct gtaacgcatg aaagtattca gccggctgaa
    30721 aagaaaaaag taattgaact acatcaatca cctacaaaaa ctgtagcgaa agaaagaaca
    30781 gcttcaagaa cctctacaca acctaaagca aatcttgctg gaaaaatcac tgtaatggaa
    30841 ccaagagctt attctgaagc tatggcgatt gctaaacgaa tcattgctgg agaagcaacc
    30901 ttagtgaatt ttcatttagt agaagaaaaa caagcgagaa gaatcgttga ttttctaaca
    30961 ggaacagttt atgcactaga tggagatatc aaacgtgttg gagatgagat ttttctttgt
    31021 acaccgactg ggatggagat tgacagttca accgctcaat cttttgcaga tgcgaatttg
    31081 tttgatctgt aagaggagga actacgattt atactattgc actattactt catttacttc
    31141 aacgggcagc ctatttctat agcattatct tgatggtata tgcattgctc tcttggtttc
    31201 caggcgggta tcaatcaggg ctaggacgat tattagctaa gatctgcgaa ccgtatatca
    31261 gtttgttcga tcgtctgcct ttgaggattg gacccttgga tttcacaatt ttaggggcaa
    31321 tcctgatctt gaacttagcc gtacaaggtt tagcacagat cgttatatgg ataactgtcc
    31381 atttagttta ttgattgaag caacaaaatc tttattctca gaatagatag gaggggaaaa
    31441 ttttggatgc aaatgtatac cagcactttc gggcagatga acgtacattt atcgattcgg
    31501 taggcgattg gattgaacag gttcaaggac aatatgcacc ctatctgacc gaatttcttg
    31561 acccaagaca atcctatatt ttagaaacac tgattcgaca aagcagtgat ttgcgtttca
    31621 tgttttatgg cggatatgaa caggcagaaa gaaaaagatg tttgattttc cccgattatt
    31681 acgaacctgt agaggaagat tttgaaacag cattgtatga aatccattat cctagcaaat
    31741 ttgccagcct aagtcatggg aaaatccttg gaactttagt gggaacgggg atcaaacgct
    31801 cttactttgg cgatatcatc tcggacggtg atcgctggca agtatttatt gcaaatgagg
    31861 tggatcattt tgttgctgca caagtaacaa agattggaaa ggttgctgta cgcttggaac
    31921 caatcaaata cacagaaatg attatgccga aagatagctg gacacaagaa agaggaacag
    31981 ttagttccat gcgactagac agtgtgatct ctgagattta taatatttcc agacagcggt
    32041 ccaagcagct gatcgaagct ggtaaagtaa aagtgaactg gacagaaaat acaagacctg
    32101 attttgtact tgaactatta gatattattt cagtcagagg ttatggcaga gtccagatcc
    32161 aagaacttga ggggaagacg aaaaaagaaa agtacagggt actgttcggt gtattacgta
    32221 aataaaataa aaaggtggtt tactcatggc tttaactcca ttagatatcc aaaataagac
    32281 attcccgaca aaaatgcggg gatataatca agacgaagta gatgatttct tagatttagt
    32341 tgttcgtgac tatgaggaat tgactcaaag aaatcgagaa ttagaaaaag cagtcaaaca
    32401 ttctgaagaa aaacttgagt acttcaatga attaaaagat gctttgaacc aatcaatcat
    32461 cgtagctcaa gatacggctg ataaagtaaa aacaagtgca agcaaggaat ccgaagtgat
    32521 cgttacttct gcacaaaaca aagcagatga gttagttgcg aacgctgaaa aacgtgcaca
    32581 tcaattaaca actgatgcag aagaaaaagc aagaaaaatc ttgacagatg caacagaaaa
    32641 agcaagacag cttgcgacag aaactgaaga tcttaagaaa aaaacacgag tattccatca
    32701 acgtatcagc ttgatgcttg agtctcaatt agaacaagtg aaaagtccgg aatgggatga
    32761 aattttacaa ccattctcca gctacgtgac tgacagccat gaagtgatca aagaagtttt
    32821 agcaaaacag cttgacaatg aaaatgatac tgatgtaaac tcagacacag gagtcataga
    32881 agcacctatg acggcatttg atacacaggc tattgatatc tcgatcgtgc ctggtgaaaa
    32941 tgaaaacgag tagaacagaa aagcactttg ttattcttaa agcgagccga tgagagtgga
    33001 agttcggtaa gacactgcat ggtgaaagat cctctacttg agacctgctt ttccgaaatt
    33061 agagtaagaa gcagcggctg acctcgttat tggtcacaga gagtttgcac tagatagatg
    33121 caactaaatt tgggtggtac cacggcatgt tcgtcccttg cggctgaaca tgcttttttg
    33181 tgtccggaaa acaaataaag gagtgtatgg ttgaatgaaa atgaaagaaa ccttgcaatt
    33241 aggaaaaaca aaattcccta tgcgtggtaa tttgccaaac cgagaaggcg agtggcaaaa
    33301 agaatgggaa gaaaatcgaa tctaccaaaa aagacaagag ttgaacgaag gaaaacctag
    33361 ctttgttctt catgatggac ctccatatgc caatggtaat atccatttag gacattcatt
    33421 gaataaaatc agtaaagaca ttatcattcg ttcaaaatca atgtctggct atcgtgcacc
    33481 atatgttcca ggatgggata cacatggatt gccgattgaa caagtattgg ctaataaagg
    33541 cgtgaaacgt aaagaaatgt ccatggcaga atacttggaa aaatgtcgtg aatatgcact
    33601 ttcccaagta gataagcaac gagcagattt caaacgccta ggagttgcag gagattggga
    33661 acatccttat gttacattag atccttctta tgaagctgca caagtacgcg tatttggtaa
    33721 aatggctgaa aaaggctata tttacaaagg attgaaacca atttactggt ctccgtcaag
    33781 tgagtcttct ttagcggaag ctgaaattga atataaagat gtaaaatctc catctatttt
    33841 tgtagctttc aatgtcaaag acggcaaaga tattcttgat gaagatacag cttttgtcat
    33901 ttggacgaca acaccatgga cattgccagc aaaccaaggt attgctgtaa atccaaaatt
    33961 tacgtatgta ttggtggaag ccgatggccg taagtttgtc gtagcgaaag atttgctaga
    34021 aacagtccaa tcagaaatcg gttgggaaaa tgtaacagtt ctaaaagaat ttgctggaca
    34081 agaaatggaa tatatgactg caagtcatcc attctatgaa cgtgaatcac ttgtgatttt
    34141 aggcgatcat gttactttag acgctggtac tggattagtc catactgctc caggacatgg
    34201 ggaagatgac tatatcgctg gtagcaaata taaactatct gtagtgtcac ctgtagactc
    34261 aaaaggattg tttacagaag aagcacctgg atttgaaggt atcttttatg acaaagcaaa
    34321 tcctatgatc actgatctat taaaagaaaa aggagctttg ctgaagctag atttctttac
    34381 tcatagttat cctcacgatt ggcggacgaa aaagcctgtg atctatcggg caactccaca
    34441 atggtttgca tctatcgata aattccgtca gaatattttg gatgaagtag aaaaagtaga
    34501 gtgggttatc ccatggggta aaacacgttt gtataatatg atccgtgacc gcggcgattg
    34561 ggtaatttcc cgtcagcgtg catggggagt accacttccg attttctatg ctgaaaatgg
    34621 agaagcaatc atcacaccag aaacaatcga acatgtggca aaattatttg ctgaacatgg
    34681 atcaattatc tggtttgaaa aagaagcgaa agaacttctt cctgaaggat ttacccaccc
    34741 aggttctcct aatggcgaat ttacaaaaga aaaagatatc atggatgtct ggtttgattc
    34801 tggttcttct catgaagctg ttttacgtca gcgaccagaa ttatcattcc cagcagatat
    34861 gtatttagaa ggatcagacc aatatcgtgg ctggttcaac tcaagtatca cgactagtgt
    34921 ggctatcaat ggtgtagcac catacaaatc agttatttct caaggatttg ctttagatgg
    34981 tgaaggccgt aagatgagta aatctttagg aaacatcatt gcaccagaaa aagtgatcaa
    35041 acaatttggt gcagatatcc ttcgcttatg ggtatctagt gtagattatg aagcagatgt
    35101 tcgtgtttct atggatatct taagtcaagt ggcagaagta tatcgtaaaa tcagaaatac
    35161 gatgcgtttc ttattagcga atacagaaga tttcgatcct aaaaaagata ctgtttcgta
    35221 caatgattta cgttctgtag acaaatatat gaccgttcga ttgaaccaag taatcaaaga
    35281 aatccgagaa gaagggtacg acaaatataa cttcatgcat atttaccgta cagttatgaa
    35341 cttcttgacg gttgatctat cgtcattcta cctggatttt gctaaagatg tagtttatat
    35401 tgaagcagaa gatgattatc aacgtcgttg catgcaaact gttttctatc aaacagctgt
    35461 agctttgaca aaattattga ctcctatcat tccgcataca gcagaagaaa tctggtcatt
    35521 cctgaaagaa gaagaggagt acgttcagtt aagcgagttt cctggttatg aagagtttgc
    35581 aaaccaagaa gaattgatgg atacctggac tgctttcatg gacttccgtg ataatgtctt
    35641 aaaagcattg gaagaagcaa gaaacagcaa attgattggt aaatctttgg aagcaaaact
    35701 aactgtttat ccaaaacaac aagttcgtga aatgttaaaa gctttggatg cagatattgc
    35761 acaattattg atcgtttcac cagactactt tgaagttatg gcagcagatg aacaagtgcc
    35821 agataacgct atggtatttg atgatgttgc tattacagtg gaaaaagcag acggggaaac
    35881 ttgcgatcgc tgtcgccaag ttcgtaaaga tgtaggagta gatgaaaaac ttcctcatct
    35941 atgcggtcgt tgtgcaaaaa tcgttgaaga cttctatcct gaagctgtag ctgaaggatt
    36001 cgaagaaaag taaaagggaa aagggggtgt gacatgttct ttgtcacacc cccttttgtt
    36061 atcaatcgtt taattttcca cgttcacgat accagttatc tggttgccag atccattcga
    36121 atccgtcttt ttcaagtagt tcgaaagctg ctttaggtcc cattgatcca gctttgtagt
    36181 tgggaaaatc cggttgtgtt tggtcccaag cttttcgaat gacatccacg atatgccaag
    36241 attgagcgac ttcttcccaa tgagagaagt tcgttccatc accattcaac gcatctaata
    36301 gtaatttttc gtaagcttct gggctatttt caaccatttc tgcactattt ctaaattcca
    36361 atttgattgg ttccgtttca aatccttgcc ctacttcttt cccattcaag gataaagaaa
    36421 atccttcagt tggctgaata tagatcgtta gaacattagg tggaagtgtc gtatcgtcac
    36481 atggttcatc gacagatgtt ttgaatacat taacaggaac ttgtttgaat acgatgttga
    36541 tccgagtccc tttttcagtc aaacgtttgc ctgtacgtac atagaaagga acacctgacc
    36601 aacggaagtt atcgatagtg aatttgcctg cgacgaatgt ttcagtctct gattgagcat
    36661 ccactttgtc ttcttcgcga tagcccttga attgtacacc atccaattca ccttgagcat
    36721 attgcccgcg aacgaagttt tctaacactt cttcttcgtt ataaatgcgg atagctttca
    36781 atgctttgat cttttctgta cggatttctt tttcggaaaa tgctactggc ggttccattg
    36841 caagtaatgc tacaacctgt aaaatatgat tttgcaccat gtctttaagt gcgccactat
    36901 gatcgtagta gcccccgcga tcttctacac cgaggttttc gccaaaagta atttggatat
    36961 tgtcgatata gcgattgttc cattgagcct caaaaatatt attggcaaaa cggatagctg
    37021 agatgttttg gatcatttct tttcctaaat aatgatcaat cctgaaaata tcttgttctg
    37081 ggaatacttc tctgatttgc tggttcaatt caaaagcaga ctggtaatca gaaccgaacg
    37141 gtttttctat gatcaaacga ttgaagccat tttttgtcat aatattttgt gatttcaaat
    37201 gagaaacgat cgttccaaaa aattgaggtg ccatagccaa ataatagaca cggttaccgt
    37261 ttaattgata gtgtccatct aatcggtcag acaattcttt taatgtctga taatgcgttg
    37321 aatcatttac atcatgggat tgatagtaaa aatggcttgc aaaggtagtt gcttcttcat
    37381 ctgaaggatt caatgcacgg attgtttctt tgacaacttc acggtagtgc tcatcgctcc
    37441 agggacggcg agcggttccg attacagcaa aatgctcgcc taaatttcct tttctgtaaa
    37501 ggcggaacaa agacgggtac aatttacgct gggctaggtc acctgtaccg ccgaatatcg
    37561 taaacaatac atttttttca ttagacatgt ggatacactc ctttatattt tatcgacaaa
    37621 aatcgtgctg gccgccttaa agctgacggg gattttcttt ctatcatttt ggatagtgat
    37681 cggtccttca taagctgcga tgtcaacgat ctcatattct tcgttgatat tcaggtcaat
    37741 agtgactaag taatccaaca attctttttc atcaagcact cgtgcgatac gcacttttgt
    37801 accgacagga taggactcca atgtttgtcg gcgttcttca tggacaactt cctctttttt
    37861 aggaatcgat cctccatgag gacaatgttc aggatgattc aaatagtttt ctaaatgatc
    37921 tgcaagatgt tccgaagtca catgttccaa tacttcagca tcatcatgga cttcattcca
    37981 gctatagtct aaatgttcaa ctaaaaaaac ttcccataag cgatgtttgc gaatcagact
    38041 gctagctttt tgcagtccgc ttgcagtcaa ttgtacacct tgataagggg aatgttctac
    38101 aagctcttct ttcacaagtt tagaaatcat ttcactgaca gatgcagctg agacatctag
    38161 actagatacg atttgtttat tgttgacttt cgttgtatct ccacctagtt ctaaaatgat
    38221 tttcaaataa tcttctcgat ttggtgtcat attcgatcat cctttcatgg taaaaaacca
    38281 tcattagtaa gtgtaacaaa aaaaacgtta attgactatt tttctaaata aaaaacaaag
    38341 gatttttaga cgtttttaca acaaaaaacg aaagatgata gagaagactc attctttcgt
    38401 ttataaagga tatatatata cattgggagg gatctatttt tcagataaca acttatatga
    38461 agtgtctgca gattcgtcat aaagagtttg ttcgggataa gaaaagataa gataaaaacc
    38521 atactgatca cgtacgacta aacgatattc atctatttct accacagatg tgccaagaga
    38581 ctgaccgttg atcaaaaacg tgtaatcaga tgtaatctgt aattgttgtt tttgctggct
    38641 atcactaaag aaccatgtac cttgatactt tgagagtcct tctgactttt ccgcttgttt
    38701 tttctttttc aagtaaataa aacttgagag aacggtaatg agtgaaccaa gaaaatagat
    38761 catttttttt atcaccaaat cactccttta tgagaaaata atcgcataga catattcttt
    38821 cttctttatt tcattgtacc gaataaaagc taaaatttct ctaagacttt cgactggttt
    38881 ttttactgtt tttctacaaa ttatgatagg atacatagta ggaagaaagg tgacataatt
    38941 tgaagtatca gcaagtggaa atagcttttt ttattgaccg cccgaatcgg tttatagcac
    39001 attgtatgaa aaaagacgga gaaataatta ttgcgcatgt caaaaataca ggtagaggaa
    39061 aagaggtcct gataccaggc gctgaagtgg ctattgtatt tgctcctgga cctaaacgga
    39121 aaaccgccta tgatctgatt gctgtaaaaa agaagggtga ctggtttaat atcgatagtc
    39181 aattgcctaa tcggctggca attgatggta ttttagacgg cacgatcctt ttaccaggat
    39241 taactggtcc atttacggta tacaagcgtg aagtaactta tcttcactcc aaatttgata
    39301 tttatttaga gacggtggtc ggacaaaaag catttgttga agtcaaaggt atgacacttg
    39361 aaaataaagc gattggtgct tttcctgatg cgcccacact cagaggattg aaacatatag
    39421 gagaattaac gtatgccgca caagatggtt atgccgctta tgtcttgttt attgctcagt
    39481 tcgaacatct tcatctggca acgatccatg aagaaatgca accagcacta gctgatatgg
    39541 ttcgacatgc gcagcaaagc ggagttcaaa tcctcgccta taattgtcaa gtatcggcag
    39601 atgaggtaac tgtcaagcag gccattccat ttgatgtaga tatccctttt gaagatccta
    39661 tacaatagaa agaaggtaaa ataatgatca acttaggtat tatcggaaca aattggatta
    39721 ctcatcaatt tgtccaagca gctttaagca caaaaaaata tgaattgaca gcggtatatt
    39781 ctagacattt ggaaaaagca caggaatttg gttctcatta tgaaggggat atcgaattcg
    39841 caacagattt gaagactttt ttcaatatta ctcatatgga caccatttat attgcttctc
    39901 cgaatagtct tcactttagt caagctaagc aagcaatttt ggcaggaaaa aatgtgatag
    39961 ttgaaaagcc agctttttcg acgccaaaag aaatggatga aatcatccat ttggcaaatg
    40021 aacacaatgt gtattttttt gaagcagcaa gaaatatcca tgaatcaggt tttaaaaaga
    40081 ttgccgatta cttaccatta aaagacgaga taatcggtgc aaatttcagc tatatgaaat
    40141 attcttcgcg ctatgaccaa gtattagatg gagaagaacc gaatatcttc tcgactcatt
    40201 tctcaggtgg tgcattgatg gatttaggtg tttaccttgt atatgcagct gttgcttggt
    40261 ttggaatgcc aaaagaagtc cattatttcc caagaaagat ttctactggt gtagatggtc
    40321 ttggatgggg gatcttacgt tatgagaatt ttgatgtatc gatccagcca ggtaaaatcg
    40381 gtgattctta tttaccgtca gagatttatt ttgactcagg aacgctagtg atgaatggag
    40441 tcaatgcaat tgaacaagca caatttcatg atcgcgcgca taaagaaatc attgatttgg
    40501 cggtaacagc tgcagaaaat ccaatggcag atgaagcaga ggattttgcc aatgtcatgg
    40561 ctcatccgaa agatccagct tggggattgt tgtatgaaga gtggatcgag ctagctagaa
    40621 atgtgaacca agtgatttat gatttaagaa aaaatggcgg catcaaattc gatgcagata
    40681 atgaggaaga tttttaatga acgaatttgt acaagtattt cccgaaaatt ggcagaaaaa
    40741 atatgaggat aaagggttta tctcaccttc tcttattcaa cgagcagttt ttcagccact
    40801 aagtaataaa caaagtatag tagcggtttc tcctacaggt tcaggtaaaa cactggctta
    40861 tctttggcct ctactactaa acgtggaacc aggtgaagca agtgcgttgg tcatttttgc
    40921 ttcttctcaa gaactagcta ttcaagtagc agatgttgca cgtgaatggg gaaaagacaa
    40981 agagttgaaa gtccaatctt tggtgggcgg agccaacgtc aaacgtcaga ttgagggttt
    41041 gaaggaaaaa ccagaaatct tgattggtac accaggaaga atattggaat tgatgaaagc
    41101 aaaaaaaata aaagcacatc aagtgaaaac aatggtattt gatgaagcag accagctatt
    41161 tgacgctggg aacagccaaa tcattgatca aattcttcat caagctccaa cagagtatca
    41221 gctagctttt ttttcagcga cagcagatcg ttcccttgaa agcattgaaa aaatcactgg
    41281 gaaaacgttt gagacaattg acgtgacagc agaggacgat tctcgaaaag gactgagaca
    41341 ttacttttta cgtgtaccga tacgaaagaa agatgactac ttgagacgtc tcacgcatat
    41401 agaagatttt catggtctga ttttctttaa tcaactgact gaattaggcg taatggaaga
    41461 aaaattgctg tatagaggtg taccggtagg aagtctggcc tctgatcaga acaagctact
    41521 ccgaaaagca gcgctagaac aattcaaaaa gaaaatggtc agagcacttt tgaccacaga
    41581 tgtggcggct agaggtttag atattacagg tcttccttat gtagtgaatg cagaagttcc
    41641 gttaagtgaa gaagcttatt tgcatcgttc gggaagaact ggtcgaatgg gtaatgaagg
    41701 aatagtaatt acactcgtac aagataataa tctaagagat ttaaaacggc ttttacgtcc
    41761 atcaaatata acacttgaag agattttttt atacggaggt aagctgcaaa ctgagcagcc
    41821 aaccaaagaa gatgcagctc ctgcagtaaa taaaaagtat gcgaaaactt tttctggaaa
    41881 ggagcagaac ccagaatata acaaagaaaa aataagaaaa aaagttaaaa ataaatcaaa
    41941 aaaagagaga aataaaggag caaggcgcaa ataagcgcct ttttatgcta tgattatgaa
    42001 aacgggaaca aaattggttg ccagaggagg ggttatgtga aagaacgtca agaagagatc
    42061 ttgcagctat tgacagaaaa ccaacaagga ttgacagcaa gtgatgtagc tgagcgctta
    42121 actatcgatc gaagcaatgc aagccgatat ttaagtgaac tatacaaggc ccatcatatt
    42181 gtaaaaaccg ctggccgacc agtcgtttac tctttgccaa cggaaaagtc aaaatctgat
    42241 gaagtgcatg tcgactcttc tacgcaagtg acttttgaaa cactcgttgg agaaaatgat
    42301 tctttaaaag tcagcataca gcaggcaaaa gctgcgattc tttatccacc gcgggggttg
    42361 catacgatta tttttggaga aactggtaca gggaagtcga tgtttgctga atgtatgtat
    42421 cattttgcaa tcgattcaga gatgctttct gcagatgcgc catttgtttc tttcaattgt
    42481 gcggattatg ctcaaaatcc gcaactgctc tttggacaca tctttgggat caaaaaaggg
    42541 gcttacacag gagcagctca agatagtccc ggtctaatag ccaaagcaga cggcggtata
    42601 ttgtttttag atgagatcca ccgtttaccg ccggaagggc aggaaatgct gtttactttc
    42661 attgataaag gtatttaccg tccgcttgga gaaagtgcac aagtacatga agcatctgtt
    42721 cagatcattg gggcgacgac tgaatcttca gaaagtttct tatctacgtt caatcgacgg
    42781 attcctatgg caatcacctt gccgaatctt gcttcacgtt cactggatga gcgttatgaa
    42841 atcatctctc tttttatcaa acaagaagcg aatcgtttga atcaacgtat cgatatcgaa
    42901 aaagaagcga ttcttgcctt catgctttat gatgcggaag gaaatatcgg tcaagtgaaa
    42961 cgagacttga aactagtctg tgcaaaatct tttttacatt accgtactca tcatgagaaa
    43021 aagctaatca ttcgaaaaga agaactttcc cttcaagtac aaaaaggatt actgaaaatc
    43081 aaggaaatac cggaacgtct cgaccgattc atggacagca aaagtcagta tttgacattt
    43141 gaaccaggat ttgctgatgt tgtctggtca caagatccag aacgaaacat gcaggtctat
    43201 aacgatattg aggaaaaagt cacttctctt tccgaaaccg gtgtggagaa cattgatcta
    43261 gagaccctca tttcaaaaga tgtggatgct tatttccaga catatgtcaa agaattgact
    43321 aaaagttcga ttcccaaaga tcttttgcca gatgaaatct ggcggttaac caatcaattg
    43381 tatgatgtgg ctgaaaaacg gttagaccgt atttataatg aaaaagctcg ttttgctttt
    43441 gctttgcatc tgcaaagtac attggatcgt gtgagagaag gtcatatgat cgtccaccca
    43501 gatttgaata acgtacggaa aaattttaag agggaattcc aggtagcaat cgatctttca
    43561 acgatcattg aagaagaaga acaagttgag attccttttg atgaaatcgg ctttattagt
    43621 atgtttcttt ctatcaatct aggagaaagt gagcctgtta aagaaaacaa agtagatgtt
    43681 ctcatattga tgcacggcag acagactgct tcaagcatgt tggagatggc acaagaacta
    43741 ttaggaacaa aagtagggaa agcttttaat atgccactgg ttatggaagt tcaaacaatg
    43801 tatgaagaag tgttacaata tgtcaaaaac tatcaagagc atttgacgaa tggcctactc
    43861 ttgttaacag atatgggatc attaaacacc ttcagtgatt tgatttatga agagactggc
    43921 attcggacga aagctatcac gatgacaagt accatgattg tgatagaagc gatacggatg
    43981 gcaagtgttg gaagaagctt agaagatatt tatcaaaata tccagctttc ctttgaatcg
    44041 atcgtacgtg atcagttcaa agcggaaaag tctgaaactt tacagcgtaa aaaagccgta
    44101 atcgtgacat gctttactgg tgaaggagta gctgccaaat tatatcagcg tattatgcca
    44161 gtgattaatc aaaataaggt agaactgatc cagatgcagt ttttagaacg tgaatcattc
    44221 aaaaaacaca tcgatgcctt attggaagaa tatgagatca aagcaattgc gggaacagtt
    44281 gatgttgatt atcaaaatat cccatttttt tcagcctatg acgtttttga tgatgaaaaa
    44341 ctaaatattt taaagcgtat agctgatgat gagatcccga cagctaaaat tgtcgattca
    44401 cttgctggat cattaagcga tgtcttttct attgatgaac tgatccgttc attgcaaaag
    44461 acagttcagc agatccagac cgatttgtcg attatcgtgg aacctggagt agatactgga
    44521 atcgttatcc atttagcctt catgttagac ggattgatca aacaagaaag ccatcggcaa
    44581 tttgagaaac tgtctatttt ctcaaaaatt tatcgtttgg aaatggatat cgttcgggca
    44641 aacttgatgg cactagaacg aaaatatcag gtaaaaattc cagaagatga tatcgcattt
    44701 cttacacaaa tgtttcttga aaataaaata aaaaaatgaa cacactaatc atactgttta
    44761 cacactaaac atctgtgtgc gcactataaa aaagagctaa aaagcatgaa aacgctattt
    44821 cagctctttt ttttattggc atgcttcttg cgttatataa aagtgtaaaa aaataaaagg
    44881 agtgttaaaa atggcaaaaa aaacaatcat gttagtttgt tcagcaggga tgagtacgag
    44941 tttattggtc acaaaaatgc aaaaagcagc agaagaaaaa gggatggaag ccgatatttt
    45001 tgcggtctct gcctcagatg cagataataa tttagaatct aagaatgtcg atgtattatt
    45061 attaggtcct caagtacgtt tcatgaaagc tcaatttgaa caaaaacttg cgcctaaagg
    45121 tattccatta gatgtcatca atatgcaaga ctatggcatg atgaacggag aaaaagttct
    45181 tgcacaagca gaaaatctaa tgaaataaat caagtatgca gttgggggta taacaacgtg
    45241 gaagatcaac aaaatctaga agccatcatg gggttaatca tgtttggcgg taatgcaaag
    45301 agcgatgcaa tggaagcgat tgcggctgct aaaatcggtg attttgagtt agcggatagg
    45361 aaaatcgctg atgcagaaga atcacttata caagcgcatc atgcacaaac agacatgttg
    45421 acacaagaag cacaaggaaa tcatatgcaa gtgacattat tgactgttca cagtcaagat
    45481 cacttaatga catctattgc gtttactgat ttagcaaaag aaatcatcga actttatcgt
    45541 cgcgtataca gcgaataaat acaacttctt ttttgaacgg aagaagaaaa atttttgaac
    45601 ggatttttta ttttgttata aggagaactc tctttatata aaaaacttat aggaggaagt
    45661 aaaaaatgaa cggactatca agttggatgg agaaatacat cctgccggtt gccgcaaaaa
    45721 tcggagcgca aaaacattta gttgctttgc gtgatgcttt tatcggcaca ctgcccgcaa
    45781 caatggcggg atcagtcgct gtaatgatca atgcaattat tcgtgattta ccgcaacagt
    45841 ttaacagtac ctatgctgac agtttagcag cagacaaagg aatctttgcc gtattgaatg
    45901 tcatcatcgg aatcaatggt tttgtctgga acggtacact agcaatcgcc ggattgatct
    45961 ttgccttttc ttgggggtat aatcttgccc gagcttatgg agtaaatgat ctagctgggg
    46021 ggatcgttgg tttagctacc ttgattcaag gtatttcctt tggtccagca ttatcagcag
    46081 cattagatgt gaatgttcct tcaaatgtcg cagatgcaat caatagttct gagattggtg
    46141 caacgattgc agatggcaca ctgtcagttg gattatgggg ttggctaaaa ctagatcatt
    46201 tgaatggaaa cgcttatttt acagttatga tcatgggagc tatttcagtc attatttttt
    46261 gtaaattgat gcttgccaac attacgatca aaatgcctga ttcagtacca ccagcagtat
    46321 ctaaagcatt tgcagccatt ttaccagcga cgatcgcttt atacgtcatt gctattatca
    46381 attatatcgt aggtcgtgta gctgatgggc aactgatcat tgatttggtg caaaaatata
    46441 ttgcagaacc attcctagga ttatctcaag ggttgggagc agtattgatc gtcacagtat
    46501 ttgttcaagt attctggttc tttggtattc atggaccaaa tgtattggca ccagtgctag
    46561 agggaatctg gggacaagca caactaatca atattgatat tttccaaaaa ggttataacg
    46621 gaaaaactgg tacaccagcc gtgttagatg caatcgaaga tggaaaagct tatatgtggg
    46681 tccgcggatc gttcgatgct tttgcatggt ttggcggatc aggcggaacg atcgtcttac
    46741 tgatagctat cttgattttc tctaaacgtg cagattatct aacagtagct aaattatcca
    46801 ttgggcctgg tatcttcaat atcaacgaac cagtgatgtt tggtctgcca atcgtattga
    46861 atgcaatcat gtttatccca ttcttgattg ctccagtagt agcaacagca attggatgga
    46921 cagctactta tcttggccta gtcgctccgg tatcgcagca agtcacatgg gtagtaccgc
    46981 cgttcttatt gtcattctta gcaacaggag cggattggcg ggcaccgatc gtaacattag
    47041 tatgtatggt cgtgactttc ttgatttggg caccatttgt catctctgca aacaaaatgg
    47101 accctgccgc aggcgaacaa caataagatg aacgtgagga gcgggacgct ttaagtttcg
    47161 ttcctcataa tgaattttct aggaggaact gaaatgatta caattgccag tgcaatgcaa
    47221 caagatgaaa tcaaagaatt gttagaagga tacaatgaag aaggaatgac ttttacattt
    47281 aaagaaaaac aaggaatcaa gctgttcttt gaaacaagtg cagaagatcc ggaagttgcg
    47341 gctaaaaaag caaaggaact aatcaaagca cagccttggg gaacagtcct ttattttcaa
    47401 tcaacagctg tttagaaaat ggtttaaaaa gataggatgg ttgagatgat aaaaaacggt
    47461 ttatttttat gtagtattgg ttctttgatc gtgttgtata gtttgaatcc acattcgcaa
    47521 aggtatgatt tgtatagtat ggtcacaggt ctttttctaa caggattagg aatctatttc
    47581 ttcatgaagg ggaaaaaaag agaagaagca aaggagaaaa ataactaatg gaaatcacga
    47641 aaaaattaaa tattccagca tcgttttttt acgataaagt tatggactct gtccttttcg
    47701 atgtacgtaa agcgaccggc aaatcagtaa ctagaaaaca gctgaaaaat ttggagtacg
    47761 tcaaacaatt ctcgcaaaat aaccgggctc gcataaaaat cgaagaagtc attgaaaacc
    47821 agtcttataa gtttcgtaca tcgacaacga agaatgaatt cgtcgttcat tatcaaatca
    47881 aaccattgga cgattcgacc tgtgaggttc attacacaga aaaaatggag tcttatggca
    47941 tgcttcaaaa gttgaatgat atgcttttag gaacaatctt gatgtatttt aaacggagac
    48001 gtttcaaaaa aatgctagat atgatcgaag caacgtatta aatcaatgaa acatggtact
    48061 atttagttat tgaaaaatga agtaagctag aaggaatttt tcataggaag atagatcttt
    48121 cctgcgaatc ctcactagct tttttgtagg aaggggcagc aaaatgacaa acaaagtaag
    48181 agagctaggt gtatcttcga ttgaggaaat gtttgattta gccacttatg catttaatgg
    48241 ggcagataca cctgaaaggc gagaacgttt tcgtacactt gcggagaatt cttggaatta
    48301 cggatttttt gatgaggagg atcggctaac aagtcaagtc atggcgaccc cttttccagt
    48361 gaatttttac ggacaagagt acctaatggc cggcattggc tatgttgctt cttatccaga
    48421 agcaagggga caaggcggga tcaatcagat catggaaaag atccttgaag attgccgtga
    48481 tcgtaaagta agcttatctt atctggcgcc attctcctat cccttctatc ggcgctatgg
    48541 ctatgaacaa tcatttgata aaatcagtta tcaactaaac agtcgtgatg tgccgtttat
    48601 caaaaaaaaa tctggaaaaa taaagcgtat ggattttgaa gatgcaaaag ctgcaatcag
    48661 aagaatttat gaacagatgc cggaaaacca acgagctggt ctgaagcgcg aagactggtg
    48721 gtatacgtat aaattcaagc aaaaaggcaa ttaccagttt gctttgcatt ttgatgataa
    48781 tgaggaagca acgggatata tcgtttatca gcttgcaacg tcttccttta ttattgcgga
    48841 gtggggattt ttggatcatg atgctttttg cagccttgtt cgcttcgtaa gttctcacaa
    48901 tggtgctttt gaaacatttg aatattcatg cggctacggc ggtaatgatc aaaattatct
    48961 attagaaaat ccatttgctt ctgtaatgat cacaccttat atgatggcga ggatcgtaga
    49021 tatttctttg tttttggaaa attatccatt taaaaagaga caagctgcat ttgccctaca
    49081 aatagaagaa gatcattatg cgaaatggaa tgaaggaatc gtggaagtaa caatcgaaaa
    49141 tggaaaaaat catctctcaa aagtagaaca aacaaaactc ccaatcgttc gaggaagtat
    49201 ccaacatatc acgcagctat tattagggta tcgtaaagtg gaagagttgg tattccaaga
    49261 aagaatacag gtgacaaaag aatatgaaga aacgttaagc tcaatcttgc cacagcaaca
    49321 gccaattctt aatgactatt tttgataaaa aacgggtgat gacaatattt ttgtcaccac
    49381 ccttttgttt ttcatttggc atttgaagga aaatgttaaa gtaaatcctc ttttttcgta
    49441 aatttgaatt ttttgttttc ttttgtttta gggttttctt ttttgtggtc ttggattgct
    49501 tctttcgtaa tcttttcccg atttttttta gatgaatcta agcgttctgc gtatactttt
    49561 tcttttggct tatcattcat tggaaaggac ctccctacat tatttcattc tacctctagt
    49621 ttatcatctg ttaaggacta gtggaaacgt tttgcctaac ttataagctg atttttttag
    49681 cagataagct tgcaagtaaa aaacaaacaa gctacaattg atttattgaa attgttcctg
    49741 tagctcagta ggatagagca atcgcctcct aagcgatagg tcgctggttc aattccagtc
    49801 aggaacgtat aaataacccc tgtatccttt gcggtacagg ggtttgtttt gtatttgtgc
    49861 caaaaatgtg ccaaactagt tatcattttt atataaacta tcgaacacag tattgatttt
    49921 ttctttatcc tgatcttcaa gctctcgaac aatatgaaga taagtagaca ttgtagtttc
    49981 taaactgcta tgtcctaaac gtttcgatac gctaagtata tttactcctt gataaagtaa
    50041 aatagatgca tgtgtatgcc ttagtccatg caaagtaaat tgcttttcaa tccctaattc
    50101 ttttaatttt ttgcgcaaat atttgctgac ggcgtttgat gaaactaatc cattttttaa
    50161 gttgaaaaaa acaaaattat gagggttttt gatttcaaaa ttctcgaata attctttttg
    50221 attgatttta aactttttta agagatcaat cgtatgttta tcaatggaaa ttttcctatt
    50281 tgaagtttcg ttttttgttt ttccccattc atttaattta taattccatg ttttattaat
    50341 agtgatgatt tgatcttcga aatcgatatc ttcccatgtt aatcctagaa gttcagcaaa
    50401 tcgcattcca gtggcaccag caactaacac gagcatagga gaagagtact gcgcagaaag
    50461 gttttcttct acgagtttca ttaaagattt aaattgatca taatctaaat atttatcttc
    50521 ttttggcttc aatgaatctt ttcctttgat tactgctttt ctagttggat caaacggaat
    50581 taatccttct tctacggcat ctttcaacga cgctctaata tggttattaa acttaataac
    50641 ggtagatttt acatggtctt tagcatactt atttaaaaag cgttgatatc ccactctatc
    50701 taaatcagaa atcaataccg ctggcatata tttctttatg ttcattaacg tatcttcgta
    50761 ttttctataa gtgataggag atactgttcc ttctttataa agttgcatcc aatcctcaaa
    50821 gtaatctgat aataatagat ttttgcgatc ccctttaagg cctttgttca agttatattc
    50881 taattcgttg gcggcatctt ttgcttctcc ttttgtctta aatcctgatt ttcttatctt
    50941 cgtgtatttt ccgtcatctt ttttgtatga aatttcgtat tgccaactat ttccacgttt
    51001 gactaatctt gccataattg aatcagctct ctttctctga tacaatagga actataaaga
    51061 agcccattgt ttgggtttta ttattttttg cacatccttt ttgcttgccg gcgcaaggat
    51121 gtgctatttg tcgttttaat ggtataattg gatgtgtatt agatcatcca atcagaggtg
    51181 tttattatga ttaaagtgat ttttaaaaga ataactgaac ttccagagtt tagattattt
    51241 gttgattatt ggtatgtctg gttttttatt gttgcattgc tgataggtct agatgtcata
    51301 ttagaaagaa aacttaagta agagttgagt taataaattg aattcctaaa tgagatattt
    51361 tgtagcccat attttgtttg ccgacatcac ctaatactat ggagctaatc gttttttcta
    51421 acagaccaaa atcagataat ctatttaagc taccatctat tagctcttgt gaatagccag
    51481 acatgctgat atttccagtg aaattttcgt ttccacgact cattaagcat gctaacaatt
    51541 gaatctcaat cgatgttaat tgattcagta caagaagata atactcctcg ttatcccatg
    51601 aagcgctgtt aattcgaagt aaacaattct tataaagatt tttatacata tctattttat
    51661 tttgtgcctt tgatttttct acctcgtcat ttatcccttc gaatattcca atgagttggt
    51721 ccttgttctc taagttgaaa acatcttctg gaatttgatc gcgaatgttt tctaatgatt
    51781 cgtttaaatt tttgtagaat ttctcgatgc gtttgaaacg cttctcgttt ttagacccaa
    51841 aataaagtga ctgcacaacg ccaccaatat aaggaattgc tccaataccg ccttcaacta
    51901 ttaattcaag atattctttt ttggttagtt tttcattgct attatccata gttacctcct
    51961 attttgtcat ttcctttaca agcattgtga ctcctgatgg cactcttttg tataggtttt
    52021 attattgtgc acaatctaac tcttagtggg gcgtggttca tttatttttt acttacttta
    52081 ctattaatca tatcccattg agcataggat ttttctatgt tcgatcctct tgaactaatt
    52141 tctcctgtaa aagttacttt atcgcccttt gtaaaggtat cagcattgtt taagtccttc
    52201 gcaaaaatta catatgaaac tttaggtgtt gcagaaatat cattccaact tttatcatcg
    52261 tactctttgt ctgctataat ggctattcta gtagtcattg attcgataac agttccttca
    52321 aaagtatatg ttttaccact aatatattta gtaaaagctg tattttgctc agtagctgga
    52381 gtaatagaat aataactatc taagaaagca ccccagtcat gattatttgt ctctaaaaat
    52441 tcttcaaatt gagttaggct tttattgctg ctgttagatg tagtagtttg agtatcagat
    52501 gatgagcttt cctgtttgtt attgtcattt gcctcgtttg atgaggaaag cgagaaacct
    52561 acggtagtaa aaataatccc gataataagg agaatcatag gtgttttctt atttgttttt
    52621 ttgataaatc ttacaattaa catgattaaa cctataataa ataaaacaat accagtaaaa
    52681 ccaaatatac cgtccattaa tagatcctct ttctcttttg atattgaata ttataaacca
    52741 agcaattctt ttttcttaaa atcgaattct tcttgattaa taatcccttc atctaacaac
    52801 tctttatact ttttaatttc atctgcactt gaaatttgtg tttctttgga attattatct
    52861 aatatagatt gttgcttctc tatatatttt tttaaatttt ccatttcatt ccaatatttt
    52921 tttgtaaaca taacggtgtt ttcatctttc gtggccgcta atatacctcc gcgactttcg
    52981 tttccgccta gcaaggtaaa ttgtatataa ccattactca tacctggttt ttttaattgt
    53041 acggctgata tatttttaaa ggggatagtt ttttctcctt taataccttg attaactaaa
    53101 tttataaatc cttttctaat aattgaaata gaatcatcag ttactttaat caaggttttt
    53161 cctggagatt ttattaaaat ctctttttcc attttttctt cctcatttct gtgatatgat
    53221 tttttttgta gaagctcata tatgaggaaa gagcccgtgt tgcagcacgg gcttttttaa
    53281 tgttttgctg aaatcggttt ttttaataat tcttgatgta ttcatacata ttgccttgcg
    53341 taagaatatt ttttcttaaa atagcattgg cagacagcat aacaagtgta tctgagctta
    53401 ttctgaatag aataatactc cataaatttt tcgagattaa actgagattc atcagtcagt
    53461 tcgttctcaa tatagatatt taataaaatt agaatagcta ttttatctgc ttctgtttca
    53521 aattttgagt gaaaagttgt agaagtatcg tacaaaactg aaaattcaaa atgagaggcg
    53581 ctgaaatgtg caagttcatg agataaatga aaggcttctg cagtttcacc gtatagattt
    53641 tcattcaaaa aaatgattct gggttttgga tagtagaaac caggctcttt catctccata
    53701 taaactactt tcaaattgta ttcgctcaac atttctttca atttcaaata catacaaacc
    53761 atcactccaa ctattcattt tcctctaaag ctttagcaat tgcaatcgct ttacgcattg
    53821 tctccttaga tatttctttt ccatcaaaag aaaaaacagt atcgtcttct gataaatcca
    53881 catgtttagg ggtttctctt tcttctctac ctagaaggta gtctacagag acatcgaaat
    53941 agtcagcaat ccgacttaat tcatctgaat taggagtatt atttttccac tttgctagat
    54001 aaccgttaga atatccaaaa ttaatttcta actgccgtat agatatcttt ttcctcttcg
    54061 ccaagtcttt tattatttca taggtattca tcgataaaac aacctttcta aatgtttaca
    54121 aaaaaagttt agaaaaatac gcagaaataa tttgactaat tctgagtaat gagctatact
    54181 atatcttgta aacagattta acaactaaaa agacaacaaa aaacactatt gatatgtaaa
    54241 tgcagaccgc caagaaagct ttaaaatcaa tgtttttatg tcttatttaa ttatgctctt
    54301 agtatagagt attactcaga tactgtcaat tgaatttaga aaaaagttgt taaatttgtt
    54361 tacgaatata aaagaaagga atgagaaata tgaacacacc gcaaattttt aatttcgaac
    54421 aaaacgaagt tcggacaatt ttagtaaatg atgaaccata ttttgtaggc aaagacgttg
    54481 cgagtgtttt gggttattca aacactaaag atgctttgtc gcggcatgta gatttggaag
    54541 ataagatggg gtcgcgaatc acgacctcag gtcaatcaag agagatgaca atcatcaacg
    54601 aatctggttt gtacagttta atcttaaaat caaaacttcc ctctgccaaa aaatttaaac
    54661 gttgggtaac aagtgaagtg ttgccagcaa ttagaaaaca tggaggttat ctaactccag
    54721 aaaaagtaga agaagctttg cttaatccag atacaatcat tcaattagca actcaactaa
    54781 aagaagaaag aactggaaga ttaatcgcag aacaaaagat tgcagagtac gaacctaaaa
    54841 tctcctattt agatagcata ttatcttcta cagattcagt aacaattagt cagattgcag
    54901 cagattatgg gatgtctcca caacagatga ataaattact tcataaacta ggtattcaga
    54961 aaaaagtcgg taaccaatgg ttattgtgca aaaaacacat gaaccaagga tacacaaaat
    55021 ctcatacaac tgagatcccg aaagccgatg gtggcactaa aattgtaatg aataccaaat
    55081 ggacacagaa agggcgtcta tttatctacg aattactaaa aaaagaagga tattaccctc
    55141 aaatggattt agaggaaatt ggttagaaag gagttttagt atgactgaca ttgcagaaat
    55201 cactcaacga gatagagaaa aaatcaaaga atatgtcgaa agttcaaagt tcttaactta
    55261 caccatgctt gctgaaagat ttggaattag caaaagctac ttatctttaa ttttaaacgg
    55321 taaaaagact tctgcagaag caaacagaat tatagattcg attatcacta tgtacgaatt
    55381 gtaaagggag gaacagctaa tgcaatatct agaagcaaaa atcccaattc cagaaggcta
    55441 tgtaattatc tcccaagtgg attatgagga gttaaaaaaa gctgatgata ctggtagatg
    55501 gatgacgttg ccagaagtgc tagaacggat taacagaaaa tatgattggt ttacttctag
    55561 agttttaaag aacccaagat atagaaatat tatcgatatc gagaaaaaca aaaatggatt
    55621 tgtctattat ccagttgaag gaagagacac atatctattt ttaagaagta aaacacttga
    55681 atttttagaa acaaattttt cggaaatctt aaggaggcaa gcggatggga aaatttaata
    55741 gagcgctagt gttcagcgca ccgctaatca tctacgcttt aggactttgg ggaagcaggc
    55801 aagcgttgat aggaacgatt gtttacatgg tttggatttt tatggggctt gatgaagctg
    55861 aagctgagta cagagcgaaa aagccaaccg agggggctga ctaaaaatga atagaaaaga
    55921 gaaactagaa tgtatattac tattactcag tttaattctt tcactaattt ctctattggg
    55981 aagtttgtat ttttgatatc aacaattttg tggatttggg ttctatttag agtaaatatc
    56041 atttttgttt ggtgattaag gagtttatta aaattaattt tccctacttc aaatgcaagg
    56101 taacaagata tagcactttt aggaggaata tttagcggta cagcttcaga gtatattcta
    56161 ttatcatcga ctgatcctcc tttagcaatt aatttcttaa atggagtagc tgaccatctg
    56221 cggtttaagt tagcggatga aagttctaaa ttaactaaca tagctggttc tgttgaatag
    56281 ttagaaatga ttacttttgt ataaatcata tctgcagcga agtaagaagc attaagttca
    56341 acttctagtt gagggcgcat tccttttatt tttatccctg ttaaaaacgt actcaatata
    56401 aaacttatta ttgacatcca ttgaaaaatt gttaagtgaa aaaaattcaa aataaacacc
    56461 accagttttt aactaaatta taccaaaaag gagagaagaa ataatgcaag aattagtaat
    56521 tttgaaaaat aaagaagctg tgactacgag cttacaagtg gcagaaagct tcgagaaaaa
    56581 acatcaacat gttttaagag atattgatgc actaaaaaaa gatgtgtcca attttggaca
    56641 gatgtttgta gaaggtaatg aaccagattc atatggcaga aatcgacgag ttttcttcat
    56701 tagtagagat ggatttttct tgctggctat ggggtttaca ggaaagaaag ctatctactt
    56761 caaacaaaaa tacattgaag cattcaacga aatggaagat gttattcgca agaatactgt
    56821 tcctcaaaca attgaagata tgatgatcta tcaattagaa gaaatgaaag atgttaaaaa
    56881 agatgtttcc atgcttaaag atactatgcg aattagcgga caacaagagt ttgaaattaa
    56941 gcaaaaagga aatatgaaag ttatgggagt tctaggggga aaagaaagcc gagcttatga
    57001 agaaatcagc aaaaaagtat tctcaaaatt ttggtctgaa tttaaacgta ccttttcaat
    57061 cccaagatat ggcgagttac ctcgtaagag attcgatgat gctgtttcat ttattgaaat
    57121 gtggttgcca gaaactgcga tccgtatgga aattgatcaa ctgaacagac aacagagact
    57181 ttttggtgat gacaatgaat agagctgaag cgctaagaat agggacggca attgctaatt
    57241 gctggtggaa atactataaa ccaatcatcc taagccaaca acatattgac aagcaaaaag
    57301 catggcaaca aataaaaaag tgactccgcc ggcaagcaaa gagtcacaaa gaaaacacat
    57361 cataaggaga ttttagcata tggaaaaaga actttccact ctagatcaat atttgattga
    57421 tcctgattgg ggcaagccga aaattgagga aacaagtggt cgaaaaatca gacgaaatct
    57481 tttgacgaat gaagaactag cttgggatca agatgattta ggcaaccatg taactatttg
    57541 ggatcatgtt tatcttatcc atctatcgaa gcattcgaat aaacctgaat atatttacgt
    57601 catcgaagat ggcttgattg atgcgctaga agagtacgac agagataact tgattgatat
    57661 ctcttattac ggaccaggta agaaatacat tgctgaaatg gaggcagaat ttgatgagtg
    57721 aaatcaaagg gacaacgaac tttgaaaaac tttttagtcg taagttaaat aaaattctca
    57781 agaaaaaagg aaattttgat tatttatctt gggctcacgc gtgggagatt atgaaaaaga
    57841 atgatccaca ggcaacggta actattaatg agtacaaaca ctacagggtt gtttctggaa
    57901 ctcatcaaga ctttcttgtt gaggaatata aaccttttct tatggatgaa actgggactt
    57961 atgtatctgt ctcagtaacg gttaaaggac acacggaaac cgaattattt cctgttttag
    58021 attatcgaaa ccaaccagtt gttaaaccaa atgcaatgca aatcaataac tcattgaagc
    58081 gatgctttgt gaaagcattg gctctacacg gactgggatt atatgtattt caaggggaag
    58141 atattccaac accacctaga atcgatacaa agaaattaaa catgctagag acgattctag
    58201 aagctttcaa tgagcagatg ggtaaagata tgaccaaaac cttaatcgaa tatgttaatg
    58261 agcagacaga taaattaggg ctcttagctg ataacgttga aactattgaa cagttaagct
    58321 atgagcaatg tgccttgatg gagcgagcaa tagcagctaa gagaaaagaa ttagataaga
    58381 agtgatatga gtgtttaaac cattaatcga ttcatattca gcggttctga aaaagttcaa
    58441 aggaaaagac ataagcgcaa ccatcaatga ggaagtgaac attgatcgac taaagacgat
    58501 gtatgacggc tacgatggtg atcgagtcat tgaaattcgt tttattgatc ctagacgttt
    58561 caccgtacag caacgaaact tcatctatgc gctgataggc gatattttta tcgatacagg
    58621 catgccaacg gacttctgga aggaattctt ctactttcgt tttgaaggtg tcacagggcg
    58681 caaaataagc ctgaaagacg aatcgaatac aactgtgagt gatgccaatg tcttagcaaa
    58741 tatcatctta gatttcatct ttgaacatca tattcctttc aaagaaggct atgagatttt
    58801 acctgcgaat caagaatatt acttctacaa atgcatcaca aaaagagtct gctgcatctg
    58861 tggcaaaaca ggagctgaca tcgatcactt tgacaaagcg ctaggaagac gaaagcgcaa
    58921 agaagttgat catgcagagt acacatttgc agcactctgc agaatccatc acacagagaa
    58981 gcacaaaata ggtgtgatta atttcaaaaa taaatatcaa atcaaaggga tcaaattaaa
    59041 ccagaaaaca atcaaaaagt taaatattgg agggtaaaaa tgacagaaca tcgaagttat
    59101 tatgcgatta taccagccaa cgtaaggtac gacaaaagac ttaaaccaaa tactaagttg
    59161 ttatacggag agataacggc cttgtgtaat gaaagaggct tttgttgggc aggcaatgag
    59221 tactttgcag atttatatgg tgtgaataaa gagaccatat cgcgatgggt aagtgatttg
    59281 attaagtttg gatacttgaa tcgggaaatc atttacaaag agggtaccaa tcaaataatc
    59341 aataggtacc tacgaattaa tcaataccct attgacgaaa aacgcaatac ccctattgac
    59401 gaaaaagtca aagataataa tacatctatt aataatacat ttaataatac aaaagaatat
    59461 ataagagagt taccgccttc gaaaaaatcg aaggctaagc ccgtccgtca taaatacgga
    59521 gagtataaaa atgttctttt gtcagatgag cagatggaga aactcaaaac agaattccct
    59581 aatgattacc aagagcgaat cgaacgactg tcagagtatt gtgaatcatc tggtaagact
    59641 tataaaaact atttggcaac tattcgaagt tgggcaagga aagaaaaaag tgaacctaag
    59701 aacgcaagca gtggatacaa gcgcacagga agacgagaga agcttcctga atgggcaatc
    59761 gaccaagaag cctatctcaa gaaaaaagcg ctagaacgag ctaatagaca atcaaaagca
    59821 ccattctaag aggtggaaaa atgaagatcg attatctaga actaattaat gaaatagcga
    59881 attataaaaa gggcgaggaa ttagacgtcc tgagagacgt atatgatcaa ctcgaagaag
    59941 ctggaattga aggaattaag aatgatcgtt cgagttggag taaactcaga tactatttcg
    60001 cactctatat cgatggaacg caattaagaa atttagcata taccaaatta ctattcattg
    60061 attgtgttaa aggcttgcaa aaacatctta atgaacttga gcaggtgtaa acaagatgga
    60121 cctaaagaca tttacagcac agatcgaatt aatgcatcaa gaagctttaa gacaaagtgt
    60181 gtcgtacgaa gacaagtggc tcaacacatt tcatggcgga cgtgagagcg cacttgatca
    60241 agtactcaaa ttactgaaag gagaatgtcg ggatggataa gaaagcggca atgcagcgaa
    60301 ttatcgaatt gacttattca gaagattggc aggaagataa aaaaatagtt gcagaagtcc
    60361 aaaagctcgg taaatcaatg tggactgaaa agcccaaacg gagaacgccg agaaagattg
    60421 caatctggca tggtgatcga attctagtaa cgggtaccgc taaacagtta tctgaaatta
    60481 ctggtctgag caaaaatatt atttgggata gagctaggag cttatggatt gattcaaaag
    60541 gaagacagtt taggtatgtg gaggagaaat aatggacgaa ctaatcgcga aagtagagca
    60601 gtgggcaaaa gataagggat tggatcaagc ggatttcagc aagcaaatgt taaaaacggt
    60661 cgaagaaatc ggggaagttg ccgcttctct agctagaaaa gatgaacatg gtttaagaga
    60721 cggaattggc gatgtagtag taaccttgat catcttggca atgcaaaatg atatggattt
    60781 atacgagtgc ttggattttg cttatgacga aatcaaaggt cggactggaa agatggtcaa
    60841 tggtgttttc gttaagtcca gtgacctgaa ataattccat taatggaaga aataactgaa
    60901 taggaggata gacatgattg atgcaaaaca agtgcaaaaa cagaaagatg gaatgttgat
    60961 gtttgaagca tatgttctac catttcttaa tcaatttgaa gttttggaat gctctgccag
    61021 cggagaagaa ttggagtatg ttgtaattcg tgaaaccaaa gaaaacgttc agaagctaaa
    61081 cgaatttctt tgcactatta actgttggga tatgatagct ccaggatttt tatgtccagc
    61141 tatgggagaa tttttggaat attgtcgtct tgaagatgca ggcactttgg atttagctta
    61201 tctggtatac aactacctaa acatcaacac agatcatttg tggtttggca ctgccgaaag
    61261 aaaatgggta gtccgctaac caccaatatc aatgaaaaaa ggcggtttcc tgaaagtgga
    61321 attgccgcca ttgctgtaag gttctttacg cgactcaagg tcacagaaat ataaatgcaa
    61381 atctcttttg aagtgatcca aagctctcgg aaaatggaag ttttttgttt caaagaataa
    61441 atgagatttg cgtcaagaac ctgagagtta tttccaaaaa agcttccaaa gaaccgaatg
    61501 agctaaggac atcatgtgta aacacataat atagctctcc tttcacggct aatcataaca
    61561 tgaaaaatat tcgatgtcag taggaaaaaa ggtgaattat gaaaagaata ttaaattatc
    61621 ccggcagtaa cagattctgc aattaaactc cgaagctgat gtatcagtat caactgtaga
    61681 atattatgag cgtggagaaa gtcaagcagt cacaaatgta aaaatcgata acgtcaacgg
    61741 tcttatctgt ttagatgaag gcgatagtat gaatgaaatt gctgcagacc atgaattatc
    61801 agaaactgct ttaattgatc aaatcgaatt agctagacaa tactttgttc catatgcaga
    61861 tacctggtcc aagcataaga atgacatcat ttttccagag gaacaatgag agcaactgat
    61921 ccagtaatta tccttgagga agccaaattt atttggactc acgaagagat agagcaagca
    61981 cgcttgctct tttctcaagg agttaagccg agcaaagtag ctgaaataat gggtcaaaag
    62041 attcttgatg tcggattgct tttgctccat ctagcagaaa aaaatttgat ttgaggtgaa
    62101 aatgatgatt caacttgcag gcatccaaac agggaaaatt tatttttctg gagaaagcaa
    62161 aagcgaagcc aaccaatggc tattgaaaac ttacacgaac aataagaagc taaggaaaaa
    62221 atatcctgat ttgttgctaa aggatgatca gattatgccg gaaccgatga ttttgacccg
    62281 taaggaggga agttgaaact aaaaaaccag ccgtgtgggc tggagttgct atttcttttt
    62341 aataatgagt ttttctaaat ttaattcatt ctcacgagtt tgcgtccaat aatcagaata
    62401 atattttaat tgtttaagag taggaatgtc gtcttcggta aaattagaaa ataattctgg
    62461 agaattatct ttttttaatt gttctaatcc tgattcttta aaacgttgtt caacgagttt
    62521 tactaaattg ttgatattca tgataaatca cctttttaaa tttaatttcg atttgattaa
    62581 tcgatacaag tattatatca aataaaaaag ctgatttagg gggtcttaca aaaacactaa
    62641 aattttttca aaaagaggag gaacggtggt gaaagtcaga gaacaattca agatagtgag
    62701 cgacgaagat aatgtttaca aaataaagat cgttaatatt aatgaatatc gagaagcaga
    62761 tcacaaatat ttggttgact tatacatgaa cgataaatat ttgggagaag gattttgtgg
    62821 agattcactt tttgatgatg agcgaatttt gaaggaggaa acagaatgat ccacgaacta
    62881 aaaatactac cagaatattt tgaagcagtg acgagcggac gcaaacaatt cgagatccgc
    62941 aagaatgatc gtgacttcaa agttggtgat cagttaatac tacgtgaata taaaaaatac
    63001 attaaacatg aattacctgg actaacgaga ccaacattta gttacactgg tgactcatac
    63061 aaagcagaga tcacttatat tactgattac atgcagaagt ccggatatgt agtgttgggg
    63121 attaaagggg tgaattaaat gaaagtatac atcttagcta tcacagaggg cacatggatg
    63181 ttcccagtcg gttccggaaa aatctataaa tcaaaaacag ctgcttataa agcatttgaa
    63241 aaatacaaaa aagaaaacgg tggcggcact aacgcaaaga ttctagtggc tgataactgg
    63301 catgaagaag gtgaacgtaa ttgatttacc tgttcatttt cgtggtacta actattttta
    63361 tgctagtaat cttattcaaa aaaagatgag taaagacgaa cgaaaaattc tggccaactt
    63421 ttatttagta ttaaaaatcg aacaaaatgt gttttcggaa aggagaattg tatgggaaaa
    63481 acaaaatcaa agattaagaa gaaaaaacga cgtttggaac aaaaggcaat ccagaatgga
    63541 acggctaaga aaaaataaaa aagctacccc tttcgagata gcagcgcaat actattctac
    63601 cataaggggt ggcgtttgtg agatttcatt ggttaaaaga ttaccaagaa ctagatgagc
    63661 agattcttta cttaaagtgg aatcttaata aaagtaagct tgaattgaat cgatgggtct
    63721 gtggtgattt agcaaacgtc cgcatcgaaa agaattcgag aacttcttct ttagaagaga
    63781 atatccaaaa gatagaaaat gaattggaat tgttgatcga gcaaaaagaa gaaatgttat
    63841 tgctgataga tagcttttct ggtatcgata atcaaattgt taagatgaaa tatgttgatc
    63901 aaatgagctt agaagatatt gctgaatctg ttgggtatag ctcatcgtat gtcagacagc
    63961 gacatgcaga aattagaaag acattgaact ttttagatga gtatgaacac agacaagctg
    64021 accgattgaa aaaagaaaac gaaattgatt tttacaatag cgagaagtac aaagaacaac
    64081 tctctttatt ctaaaattac actgttcact aaatgttcgg tcattgtagc tatgtaaaca
    64141 ttgttagcag catgatattc tattagtgtc aaaaaaatat gaaagagcca agatatccca
    64201 accgttttat taattggtat ctgtggctct tttattcttt taattagtag ttggcataaa
    64261 gttatttcca tttataaatt gatcagctaa atcagcatca taatcagccg cgataaattg
    64321 cgctgctgat ttaataaatg catccatatc atgaacatct ttattagtat gtctacgaac
    64381 atagtgcgtt tcatcattac caatccaagt agcagctttg gctaatcttt ggagtttagg
    64441 aaaatcattc aaataatttt caattgtttt acctaataac atttttttta ttttatcttc
    64501 atcctctgaa tttttagata ttgcataatc tttaattaga aattctagag cttttctata
    64561 accaactcca gcaatttgtt ccaattgctc agatttagct tgtgtggctt gagtataaat
    64621 atcaacaaat gtaggagaaa ctttttcaat attttctggt aaatctattt taatcggcgg
    64681 acggtaataa tctttaatta aaatattttc agaatatcct tcatcttcat taaacgtatt
    64741 tataaattgt aaactataaa atttgttgca ctcatcattt atacactgta ctaatacgcc
    64801 aaagattcta tcattatcga acgcactata tgatgaaacc ccaaaataca catacggagt
    64861 cattatattt ccgcaatgcg gacaactatt tggcaaataa attgtctctg tattttgacg
    64921 atcacgatac ttaatattaa cttcttgaag cattaaaaca cctcgcatct tttttataaa
    64981 tcataccaca aaatatctga taggagagta aacaaatgaa tgattttcat gaagcggtac
    65041 ttagtattga agtagaatca agtttggcta aagtttataa gaaagcaatt gaagcagaga
    65101 atagtccgta cagagaaaat tggaatggta atcatgcaca tgtgcaagtg gagaatgatg
    65161 attacagaac tggaatgaat acgttagtta tttctttatt gtcacacact ctacccaatc
    65221 tgcaggaaac gattgaatgg tatgagcgaa tgggcgcaaa agtaatccgt acaaattaca
    65281 aaggagagaa ttaaaatggc aatgatcaaa attagaacat ccattagtgg aacagagtat
    65341 tgggattcag aaaagaaaag gacagtagtt gttccgaaag atcaagaacc aaattttgaa
    65401 gtaaaagaag aaaaaggaat tttgagtgat ggcaaatcat ttgttgctgt caatggcgaa
    65461 ctcatagctc atagcagtga aattcttgat agcgatggaa acactgctgc taattttgat
    65521 ggagacgaag ctactaatga tcagtccact gaagatacgg atgaactgga caatatgact
    65581 gcaaaagaat tgcgtgcata tgctaagaaa catggtattg atattcctgg tgctatccgt
    65641 gcaaaaggcg atatcataaa tcttattcgt gaagtagaat gaaatactgt cagtttgacg
    65701 gatgcacgaa caaaatagca aagggtatct actgtactga acacaagaga tcaagcagat
    65761 cacgcaagaa gaagcagcaa gcaaagtctg tttatcatca tgagaacaaa ccattctatc
    65821 gaacgcaagc atggaaagat atgcgtcaat ttatttatga aagagaaggt ggtcattgtc
    65881 agcggtgtgg tcagttcata tttggaaaga gagcacacgt ccatcacatt gtaccaatca
    65941 aagacaacga actgcttaag cttgatccaa acaatctcat gctattatgt tcaaaatgtc
    66001 atccaattgt tgaaaacgaa acggaagaca aaaaagtttt tccttcgtat ttcaattgaa
    66061 gcccccctat tcattttcaa aattttttcg cgtggggaga tagggtagcg gggagtcacg
    66121 cgcatcgtta ggtcaaattt ttcaaaaaac aaaggggggt gtatacaaaa atgacgacta
    66181 aagcgcaacg taaagcgatt attgatgaaa aagtaagtgc tgaaaaagct cgtatcttag
    66241 aaataatgaa tttgtctgat ttgtacacca tcactcttga tccattaatc gaatcatact
    66301 tggatatttt tgaaatttac caacacaaat atttattgtg gaaggaaaaa ggatttccgg
    66361 agacgcaaaa attcacgaat aaatcaggag ctactaatca atcaaaacat ccattggcac
    66421 aacaagtaga aacttgggca gataagaaga tgaaagctct agatttatta ggattaacaa
    66481 acaaagcaaa aactggtaga ctaattgctg gaggatcgac cgcaagaaaa gatgaagaaa
    66541 ttacacgccc agaagtaaag ccagtagatg aactagcagc gcacagaaat aaatggcgta
    66601 agaaggcagg tgctgaaaaa tgattgaacc tggtgtaaat tatgctgatt tatttgcaaa
    66661 agaagtaaga aagaaaccta agaagtatcc taagaccgtt cgtttagcaa tagatcgctg
    66721 gtatcagtgg aaaaaaagaa aagatatttg gtttgatgta gatcgcgcga atgaaatgat
    66781 ggattgggta gaatcattta ttgttcacac aaaaggagaa atggtgggaa aaccgtttct
    66841 tttagaaccc tgggaaaaat ttatttattc ttggatttat ggttgggtta aagaaaatga
    66901 aaaaggccaa attgtacgcg ttactcgtga ggcttatgtc cagattccaa aaaagaatgg
    66961 taaaacattg attgctgtcg gttcattagg atatgcaatg tacggagaag gggcgttatc
    67021 agttgattgc tatgcttgcg catctgattt tgctcaagcg caatatgctg ccaaaccttt
    67081 tgcagttaca atcttaaaca atccaatcct acttgaagga actaaaatat ttagggggcc
    67141 aaagggaact gtttctagta ttacttatga ctatattcat gaagatatgg cttactcaaa
    67201 taaatttatt gttcaaacca agaatattga taatatcgag ggatccaatc catattttgt
    67261 attgaacgat gaattgcata aacaggagaa aatggaacag tatgacaatt ttaagtctgc
    67321 tcagatatct ttaccacagc cattgatgtt taatatctca actgctggga aaggttcgtc
    67381 gtctgttgga atgcgtgtat atcgcgaagc aaaagaagtg ttgaaacgtg atgataatga
    67441 ttcaaacttt gttctaatct atgagccaaa taaaaattat gattggacgg atagaaaagt
    67501 ctgggaaatg tgcaatccta actggggaat atcagtcgat ttatctgctt tagaatcggc
    67561 atttaaaaca gcgcaacggt cagctcattc caaagctgaa tttctaacga aacacttgga
    67621 tgtatttgtg aacggcgcgg ataatttctt tgaacaggat caagtagagc catgtttagt
    67681 taccacacaa gaacttggtg atttaagtgg cgaaccatgt tatatcggtt tagatttatc
    67741 acgtacacga gatttgacct gtgtatcttt aaacttccca acatgggatg aagatggtaa
    67801 agcggttctt aaagtaaagc aactttattt tattccgaat gaagatttag agtttcgaga
    67861 aaaagaagat aatgttcctt acagtgattt ggctgaacaa ggtttcgttg aattttgcga
    67921 cggaaaaatg attgatcaag atcagatttt gcagtacata gaggactgca tgaatttata
    67981 tgatattcag caagtgaatt atgatccagc gatgagtgac aaacttgttg agaaattaga
    68041 aaacttagga ttggaatgcg ttgaagttgc tcaatatcct aaagtattga atgctccttt
    68101 tgacgatgtc gaacggttgt tttatgagaa acgaattcaa tttgataatc cattattcct
    68161 ttattgcact ttgaacgttg tagcaattac taacatcaat ggacaaaaag cgccaagtaa
    68221 acgtcaatca aagaaaaaga ttgatgggtt cgtggcgttt ttgtgtggtc ataaggaaac
    68281 gatgaatcaa atgacagata ttgattcaga tgagttagat gattacctaa gttccatcta
    68341 tagataaata gaaaggcggt gaaaaaaatt gaaattacgt gatcggttat cgaatgcagt
    68401 ctattctttt atggaaaaac gtggatatat cgaggatatt tttggacact acacacgtta
    68461 tggtcaaaga tatgtgacgg attcatctat catggaatct tctgatgttt atgaattagt
    68521 tcaagacata tctaatcagg tggcattggc cacaccaatt gttattggtc ccgacggcaa
    68581 cgaagtcaaa gatcatcact tactaaatat tttgaagagt cccaatgatt atttgacagg
    68641 attcgaattt accaaattgg aaacaaatac tttattgatc aatggtgaga cattcccatt
    68701 aacggatagg gatcagcttc atttggcgta cggtgtaaca actaaaatca atgaacgact
    68761 tcaagaagaa tttgaaatga atggtcaaaa aatacctggt caaatgattc gacacattaa
    68821 gaacatcgga actgattcat taaaaggtgc tggaataatt gatcttgcaa gaaacactct
    68881 agaaggcgtt ctgagcgctg aaaaagtttt gacggacaaa tatactaaag gcggtttact
    68941 tgcgttcatg cttaaactag acgcccacat caatccaaat aatagcgccc aaacaaaaat
    69001 tgtcaaagct atattggatc aactggaagg aacgcaaaat gagagtgatc attctgttaa
    69061 gatgattcct ttgggaaaag gatattccat cgagacatta aaaagtcctg ttgatgacgc
    69121 ggcaattttg aattatttag gtgtttacaa aaaagactta ggaaaatttc taggaatcaa
    69181 tgttgatacg tatcaatcgc tgatgaagac agatattgaa aaagcgatga tgtatctgca
    69241 caacaaagca atcaaaccaa tattgaaaaa caagagcgaa cattacaccg ctcttttttt
    69301 tatgcctaat tctggctata gagtggaatg gaaaattaat attttggatt ttgttcctta
    69361 ctcaacaaaa acaaatattg gctacaacat cgttcgtacc gggattacaa gtccagataa
    69421 cgtggcagaa atgcttggtt ttcctaaaca gaatactcca gaaacacaag ctatctatat
    69481 ttcaaatgac ttatctagga ttggccagaa aaatgcaaca gatgattcct taccaacgaa
    69541 tgatcaagac ttgaaaggag gtgatggaaa tgaagaagaa ggaaattcgc acgattgaca
    69601 tcaccaatct ttcaacacgt tccgatgaag aaactcatac gaggaccatt agcggctacg
    69661 ctgctgtatt caacagtcaa acacttttat gggatgactt aagcgaagtg attgttcctg
    69721 gtgcattctc aaaggcaatt agtaattcgg atgttcgttg tttgttcaat cacgattggt
    69781 ccaatgtgct aggacgtact aaaagcggaa cccttcgcct tgaagaagat gaacgtggtt
    69841 tgaaattcga agttgattta ccggacacaa cggtagcaag ggacttagtt aaatctatgg
    69901 aacgaggaga catcaaccaa tgtagttttg gttttgtgcc gactgaagaa acgtgggact
    69961 acaattctga accaatgctt cgaacaatcc atgaagtgga attatacgag gtttctattg
    70021 tgcctttgcc agcatacgaa gatacagaag ctgcattaag aagtcgtgat gaattagaaa
    70081 aaaacgtcga agaaagaaaa aaattaatca aaaaaattaa tcaagcgcta gaagcgtagg
    70141 aggaaaaata catggataaa gaattattga aaaaaatgaa ggcacgtcgt gagcaacgat
    70201 tgactgaatt acgtgaaaaa gttgaatcag gagaattacg cgaagcagat ttagaagccg
    70261 tgaaagaaga aattgacagt gttattgatg aattgaacgg aattaaagac gaattaggcg
    70321 cagattctgg aactgatgaa acagacgaca atacagatga tcaatcgaat agtacggatt
    70381 cagacgaaag ccgttctggt gaagacaacg atcaagaaga agattcagac agtgaagata
    70441 gttcagaaaa tcgttctgga atgattactc aacagcaacg agatggatta cttggatcaa
    70501 ttaagaacgg attggaggca cgtgcaaaaa tgaccaagaa acaaaaagat caacaactac
    70561 gaaaagcatt tgctaatttt gtagctggaa atatttctga agcagaagct cgagctttag
    70621 ggattgaagc tggcaacggt tcagttactg tcccagaagt aattgcatct gaagttatta
    70681 cttatgctca agaagaaaat ttacttcgta aatacggaac agtggtgcga acatcaggag
    70741 atgtcaaata tccaattctt gtgaagaaag cagatgcgaa tgtaaacaag aaagagcgtt
    70801 caactgatat tgctgaaaca gctattcagt ttgatgaaat tttgcttaat cctgccgaat
    70861 tcgatgcttt ggcaacagta actaaaaaat tattaaaaat gtctggtgtt ccagttgaag
    70921 atattgttgt ggaagaattg aaaaaagctt atgtgcgtaa agaaatcaat tatatgttca
    70981 atggtgatga cgctggaaat gaaaatcctg gtgcattagc caaaaaggct gtagcattta
    71041 aaaaaccttt agatctaact gcttcaggtg ctgggcaaaa attatatgat gcattaatcg
    71101 aatttaaaaa tacaccagtg acagaagtga tgaaaaaggg acgctttatt attaatcgag
    71161 ctgctttgac tgccattgaa aaaatgaaaa cagatgatgg atttcctttg ttgcggccat
    71221 tcacacaagc agaaggtgga attggttacc aattagttgg ctatcctgtg gattggacag
    71281 atgcagcaga taaaaagggt gaaccagaca cgccagtttt atattttggc gatttttctg
    71341 catttaaaat tcaagaagtt attggtgcct tggaaattca aaaacttgtt gaaaaattct
    71401 ctggtaaaaa tcaaattgga ttccaaattt acaacttgct agatggtcaa ttggtttatt
    71461 ctccatttga accggcagta tatcgctacg aaattacaaa accagttggt ggttaagatg
    71521 gaagagcaaa ctaaagaatt gtctttagag gaaaaattca aatcacatat tcattttgaa
    71581 gagggcatgg atgattcttt gctctctttt tatttaaata tggcaaaaga ttatgtcaaa
    71641 acagcaactg gtggccaaca agaatatctt attttgatgg ttgccggcat tgcctatgaa
    71701 tatagagttt cagaggatga actcgacaaa gctatgaatg ccatgacgcc atttatcgtg
    71761 caaggagcga ttcaaaatgc cgaagagaca gaccaataat ctcagatgga aagccgaatt
    71821 gctagacatc aaaacaggaa cagacggaaa cgatcgtcca actacaattt acgaatttaa
    71881 gcgtctaata ttctatgaag aactcggtgt gacttctcaa gaaaaatatt tatcacagca
    71941 agccaagaca gacgttgtca gacgaattaa agtcagatgg gataaatcca tcacagagaa
    72001 attaagtgcg ctcaaaattg attctgtaac gtataacatt actcgcattt atacgaatcc
    72061 cgatgcaaga gaaatggagt tgagtttagc ttatgtcgat tagctttgat gaattgaaaa
    72121 cagcgctgaa atcaacaaag ttagcagtgt tcagagacaa agccagatta gggacgatgt
    72181 atccatacat tgtgtactca aatgtgagta acagcaaaaa aatggcatcc ggtaaagtct
    72241 ataaaaaatt accttattac caagtctctt tttttacact tggaacagaa caggatttag
    72301 ttgttattga acaagcgctg caaaatgctg gcattccata ttcagatttt acaggtatac
    72361 aaggtgatga gaacgacgat accgtaacca actattacac atatgtgagg tgtgtggaaa
    72421 atgccaagta ataagaatgg tttttctgaa atatcggatt atttaggaaa cctttcaaaa
    72481 gttgatccga aaaaattatc gttggaatct ttagaagaag cagctaactt ttatctaaag
    72541 cagttgcttc ctaatattcc taagtcgctc ttaaaaaaga aacatatgcg cgatcaaata
    72601 aaagtagtag ttgaaaacga tcaagtgaaa gttcaatttg aagagacggc cttttactgg
    72661 cgctttgccg aaaatggcac aacaaatcaa cgtgcccaac attttgcaag tggtacgtat
    72721 gaacaaaaca aagaaaaaat tgaagaaatt atgactagaa aaatacttga tttatgggaa
    72781 gggtgatttt aattgggaaa acaagatact ttttattttg aaggattgga cgacatttta
    72841 attgcgatga tggcaacgcc agattctgtt ggaactgcac cgacttatag tgaagtttta
    72901 cgattgccaa ttgccacaaa aatcggtgtc aaagggaatg gaacagcatt agaaaaatgg
    72961 gcatccagca aaatgtttcg tcgtgtgtcg cgagaaacaa aacatgaact tgcgttggat
    73021 cacgtgggta ttccgataga agtgatggat gaaatcaaag gattagttgc taaaagcgga
    73081 gtaacgttta gcaaaaatac cgcacgagaa tttccgtact tcgcctttgg atttattgga
    73141 aatattgaaa atggcggtaa aaaagcagtt tggtatccta atacacaact atccaatgtg
    73201 attgacgaag agtatgccac tgcagaggaa gaaacaaaaa ttgacgatgt aactgcaaat
    73261 ctggtttcca tcggactgaa atacaataat gtgatgtatg caagttttga ttcaaataga
    73321 gacggagctt ctctagaatt atttaataaa ttcattgctc aacctgtata cgatgaagaa
    73381 cagtggaaaa cattggctaa agttggaggt gcgggttaat ggctcggtta tctgattatg
    73441 gaattcacgt tgaagactta aaaaattctg ctgttgtaat tattcaaggc gcagaattcc
    73501 ctatttcatt tactatgcaa acgatggaat ttatagcaga tgtgtatggt ggagattatt
    73561 cgcaatttga atctgatatg aacgccatgc tatctaaaaa agaaggacaa atttcttctg
    73621 ctaacttatc gcctagtgat ctaaaaatca tgcgtgcctt gatttatgcc atgctgcgta
    73681 ctggtggttt agaggaagat ccagaaacta ttttcaaatt tttgggaatg agtggagagg
    73741 tgttgtctgc ttatagtacc tgtatggaaa tttttgctag ccagacattt caggtggaag
    73801 acctaaaaaa atccaagaag ccacaagact ttcaaaaagc gcaagcaaaa agaaagaaaa
    73861 acaaaaagaa tcggaagaga taggaactcc ttggagtttt tatatttacg ttgctctcac
    73921 tctattgaat tggagtgaga gtttcttttt aaagtctaca cctaacttgt ggctcaaatc
    73981 ttatttacag tggttacaac aaaacaccga ttttgaacca cctcaatctg taactatgga
    74041 taaatcgcct tggtggtaga aaggagcgct aagataaatg gctggtaaag aatctgatgt
    74101 cgttcttaat tttaaaacga atggcgaagt cagttattcg aaaacaatca aagaaatcaa
    74161 caaagaaatg aacttagccg ctgccgagta caaaaaccaa gtgtctgcga tggacaagga
    74221 tgcaactcaa acagaaaaat tgcgagcggc taaacaaaaa ttagaaaaac aattaggatt
    74281 ggctgaacaa cgatctcaaa tgctgagaga ggaatatgaa aaatctgtca aagaaaccgg
    74341 tgaatattct gctgaatcag aaaaacttta taaacaatta ctcaattctg aaaccggaga
    74401 aaataaactt cgtacagcat tagaacagac gaacgatgca cttaaagaac aaggtgacgt
    74461 ttctgttgat acagcaaaaa aactccagaa aatcgaagaa acaggtgaga aagtaaaagg
    74521 cgttggtgaa aaaatgtctg ttggagtaac cgcgcctatt gtagcggcag gagcagcagg
    74581 acttgcagca tttggtgaag ttgacgaggc acttgatacc atcattacaa aaaccggagc
    74641 aacaggtgat caagctgata gactttcaca gtctttcaaa aacgttggtt caaatactca
    74701 tttaccttta caaacggttg gggaagctat tggtgaggta aatacacaat ttggattcat
    74761 ggataaaaaa ctggaagatt caaccaatta tctcctacag tacgctgaaa tcaatgatac
    74821 agatgtttcg caatcagcaa tatctgctcg acaagctatt gatgcttatg gactagaata
    74881 tgatgatttg aattctgtcc ttgatgtaac aacgaaaaca tcgcagaata ctggtcaatc
    74941 tgtagacgac ttgatgcaaa aagcaattga tggcgcacca caaattaaac aattagggtt
    75001 gagctttggt gaaggggtca ctttacttgg acaatttgag caatctggtg ttgattcaag
    75061 cgcagcttta agtagtttat ctaaagcaac agtggcttat gcgaaagacg gaaaatcttt
    75121 aagtcaagga ctagaagaac tacaagacaa ggtaaaaaat gcaggttctg aaacagaagc
    75181 catcaatgca gcagcagaag tattcgggac taaaggcggt cctagaatgg ccgatgcaat
    75241 tcgtagaggt actttgaacc tggaagattt agcaaaaact gctggagaaa gtgggggagc
    75301 tgtaggagac acattcgatg ctactctcga cccaattgat caagccgatc aagctatgaa
    75361 caatgcaaaa ttagcaatgg ctgacgtagg tgaagcagtc caagtaagcc ttttgccttt
    75421 ttttgaaaaa gcaacttcct tattacagga attctctaaa tggtgggggt ctctagatca
    75481 agatacaaag aattggatca taacaattgc tggtatagcg gcagcagttg gaccagtact
    75541 aatcgttctt ggttcactta tgggatctgt tacaaaaatc gttggggaag ttaaaagttt
    75601 tataggagtt tggcaaggac ttgctggttt atttggaatg tcgggaggct ggtttgcatt
    75661 agcagttata gctattggcg cattagttac tggactaatt tgggcatata ataacgttaa
    75721 atggtttcat gatggagtga attctttctt caaaggtgtt tcagatgtag ctgttgaaat
    75781 atttaatttt ttaagtggtt attttggtgg atttttcgat ggtgttatag caaatttcaa
    75841 taatttttat aatgctggaa aacgaatttt cagtggtttt ctagatttta tcactggagt
    75901 atttacaggg aattggtcaa aagcatggca aggtctagtt gatatttttg gaggtatttt
    75961 cgatggtatt gttgctgtag ggaaagctcc tattaatgcc atgattggat tgatcaatgg
    76021 atttattggt ggattgaata atataaagat accaaaatgg gttcctggtg taggtggaaa
    76081 atcattttct atttcaaaac tgccttattt agcacaaggc ggtcatctaa tcaatggaca
    76141 agcgattgtt ggtgaagctg gacctgagtt actgactgcc aagaatggta aaaccacagt
    76201 tactccatta tcagacgaag aaaaacgcaa agggatcagt ggaagagttt ctggaggtag
    76261 cattgaacag catatacaca ttggcaaagt cgatgcaaac aatccatctg agttagatcg
    76321 tatgaatcgt aaatttgcta aagcaaacaa acaggctatt cgtgatttgg gaggtgttcc
    76381 tatttgagtc gacaatttat gaatccagat gaaccaaatt ttatttggaa aaatcggaat
    76441 gcagtaattg atatgaattg catcattgag gcagagcttc cagatattat gccgaacaag
    76501 cgatacgaaa cttacacgat tcagggccga agcggagaat tgacggagac gtttgatgac
    76561 tatgaacctt ttgatttgga aatagaaggg atcactattc cacattcgaa actgagagaa
    76621 gtcaaacgat ggctcactgg taaaagccaa ttaatcacac ataatgatcc agacaagtat
    76681 ctagaggcta tctgcagcat ggataaagaa gtccctttcg aaaacgagtg gggcttcttt
    76741 tatacattcg atgttacttt tcgttgtcag ccactcaaaa gaaaaatcgg tgaagcacct
    76801 aaaatttttc attctagtgt tatggatatt tttgatcatg gtgacgaaat tgcacatccc
    76861 tatctggaaa tagaatcgaa cggaggagat ataacgatcg ctgtcggtga taaaagccta
    76921 acaatactta atacgttagc tgcaacaatc gtggttgata ctcagcttgg aaaagcaata
    76981 caagaaggtt tgaatttatt tacgcgtggt gattggccag tattgcagcc tgaatggaat
    77041 caggtaaaaa tatccggaaa atttaaagaa gtgcggtttt ggaataggag tgtgtatctg
    77101 tgacgcaaga atttatttat gcttataaaa aaatgccaga tgatttgagc gtgaacggag
    77161 cgtcgttagt tgattgggaa gatttgccag aaatcaatcg tgtgctgaat ggccaatatc
    77221 gtttttatgg taactattca agaagcggac agtatcgctc ttatttaaaa aaaggaaatt
    77281 ttataaaagc gaaggtacca gatggatcat ggcaatattt tgaaatttat aatgtcaaaa
    77341 agaatttgac ctccgtttct gtaacagctc ggcatattgg ttttatggcc aataagaact
    77401 ttattgtcaa gtcgtttacg gataacggca atgggtctca gatcatgacc aatcttaaaa
    77461 acagtttggc atttgatcaa aaatttaact atctttcgaa tgtagggaca acgcaccaat
    77521 ttacagcaag acaagtcgcg ccagttgaag caatcattgg ttcaaataac ggtaatcaaa
    77581 atttgactgg cgtgactagc gcggaacttg atatggataa ctatgatttg aaactggtaa
    77641 aacagattgg atcagataat ggttttcgga ttgattttgg catcaattta gaagcaatcg
    77701 aagaagaaat tgatgaagaa tcaattgtca atagtttgta tttggttggc ggtgttcctg
    77761 ataacgatta tgatgaagac aaagaaccta tcgaatatgg ttatttagaa attgatggag
    77821 taaccaacga gaatcgacgt attgccaaac gtgaaaacgg agattgtaaa acagttgatg
    77881 aattgatcaa atggggcaaa accttatttg acaatgatcg tatccatgag ccaaaagcta
    77941 ctcatacagt cagtatggtg gcgttggaac acacactcga atacggtgac atgtatcaag
    78001 agctagcgtc tttacacttt ggtgatgtcg ctcatgttag ggcgaaagag ctagatatcg
    78061 agataaaaga gcgtatggtc gaatacactt atttcccaac gcttgggaaa tataaggata
    78121 ttgttttagg taatgattta tcactgtaca cttcggcagt aaatactcaa gcacaagaat
    78181 tgaaaaagaa aatcgacaat cgaacagaaa cgttagttca aaatgtgttg aatgcgacgg
    78241 catggatcac tggtaattct ggtgggcatg tcgtttttcg tccagaaaaa gctccatcag
    78301 agattcttat catggatact ccaaatgtgg cgaatgcaaa gcgagtgtgg cgttggaatt
    78361 taaatggctt aggttattca gacaacggag taaatggccc gttcggtatt gctatcacat
    78421 caaaaggaga aattgttgct gacttcatca aagtaggaac aataaatgca gaagtattcg
    78481 aaacttcctt taatgcttat ggtgatgtgt taaaacttgt aaaaggcacg cttcaaattt
    78541 ggaatgaaaa caaaaaaatc atggagctaa ccaaaaaagg tatggaattc tggaatagaa
    78601 aagaatccat tggaacgatc ggaacaacag attcagcagg aaatccattt ccaaatgctg
    78661 taacacctac acctcttgag gaaaattctt tggtaatacg tacaaatggc gatggaaaat
    78721 acattttaat ttctccaact gcagaaaaag gatttgtgtt attaggaaac ggaaaagcat
    78781 attatttcgg tgatttagat attcagggaa aacttactgt tagaggtaaa gaagtgatac
    78841 caggacaaaa tggcggtcca tctggcggag gagaaacacc tggtgggtat cctgatgaat
    78901 taaaaacaga tgcagaaaag agagcttgga gaatatacga tattttgtgt aataacggat
    78961 ttacgaaaca atctgcatgt ggaatattgg ggaacattca acaagaaaca ggaggaactt
    79021 ttgatcctga tactgttcaa ataggtggac cagcatacgg attagttcag tgggatggtt
    79081 cttcatatcc tcttgttggt ccagcaacat gggatggaaa agtttatgtt caaaacttat
    79141 ttaatgctgc aggtattaaa gaaccaataa cgagcttaga tgcacaagtt cgattgctta
    79201 tttggacatt tacaaatgga caatggatgg gcgtagtaca acctacgacg gttgatggat
    79261 ttaaggcctg tactgatcca agacaagcag catatgcttt tgaacgaaac tatgaacgtc
    79321 cggcagcgac acatcctgaa cgtcaagatt atgcagttaa ctggtataac aaatttaaag
    79381 atttaaaacc aggaggagct actggagaag caggactaaa acatttagag tctttgattg
    79441 gacaacgaat tggcaatggt cagtgttatg gcttgtctgc agaatattca ggatatctgg
    79501 gtggttgtgg catgggtgct ggaacaaaat atggtttaac tcatgtgata ggaaatactt
    79561 ctgcagcatc tgatattggt attgcctatg attggtctgc tgttggttgg aaagtgattc
    79621 aaaaccctag atatgatcaa ttagtagttg gtgcaattat taattgggca agaggtggac
    79681 aagtgggttc atggtttgca gacggaactt atggacatac tggcgttatc cgaggcttag
    79741 ctaatggtcg tatgcaaact tatgaacaaa acacagagtt aggtatgatt tgtggaaagt
    79801 tagatcgcca gtattatagt gcaagtgcaa tttcttccat tgtcatacca ccaaaatagg
    79861 gaggtgattt aatggcaaag tggaatgtca tattaagtac aacagaaccc tataattacg
    79921 tggggatgat tcaagttcga caaggcaata aaaacactga agttatggaa gctacaattg
    79981 tcgaaaatgg tcttccatat gatttatcag aatgtaaggt atattttgaa tcagttgttg
    80041 gcggaaaata tccagtccaa ttagaaacaa gaattgtgga tgctaaaaaa gggaaaatca
    80101 a
//
LOCUS       DAFBVQ010000008        73467 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.008, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000008 DAFBVQ010000000
VERSION     DAFBVQ010000008.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 73467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 73467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..73467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.008"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..1087
                     /locus_tag="LLC22_000672"
     CDS             <1..1087
                     /locus_tag="LLC22_000672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5433971.1"
                     /translation="DINDDGSRKKVEKVGGDTRPEAEAALRKVLSDIDETGQYFLGTD
                     TRVKQYLDFWMEEYVKLNLKYNTYENYRFTIKNHINGYLGKKKLTDLSPALLQNFINA
                     EFKKGYSKKTMTITHSVLKNALNMAVYPWGLIKQNPMLYVKIPKYEARPTTKKDLKII
                     SLEDFDHMLEITPEGHPFYIPLNIGFYTGMRVGEVCGLTWDDVDFSNGTITVEKQMVK
                     NDGAWVYGTPKTSSSNRTIFIGQTLLAILKKHKKQQLENRMKYGKLYIDSNAVCTKED
                     GELVTPSVVKWNTRRISNALSLSFNFHSLRHTHATLLLENGAKMKEISERLGHSRISI
                     TMDTYSHVTDKMRNETVDIMENLRKNS"
     gene            complement(1307..2449)
                     /locus_tag="LLC22_000673"
     CDS             complement(1307..2449)
                     /locus_tag="LLC22_000673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171850.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5433972.1"
                     /translation="MRKIANVYKDRKRGTWFFSATLGQDRFGKRIQVTRRGFKTQGEA
                     RRGLEELKQSFSDSQGICLQGITFHDFYREYFFPWYKLGTVEKTYMKTDHILQRALDF
                     FGEMQVVKIRPIHIQEFQQFLSKIHVVKKGIEQPLSPNYIKQIFNKLRVVFKRAIVLE
                     IIEENPVDTIGKIKTQRPQVEFWTVDEFKKVYNSVYHGDFYEEFYKRLMRFIFVTGVR
                     SEELLALQWKDFDLINGRCSVNKSIYIRTRQDYEFAETKNTSSIRIISLDRQTVEDLK
                     TWKKTQQSIGKNIELVFSFDGLPPSPRTILSRIKKLAEIAGVKPIHMHGLRHSHVAFL
                     IEHNKNIYAISKRLGHASIKTTLDKYGHLYPETNQALANEITRFDI"
     gene            complement(2454..2639)
                     /locus_tag="LLC22_000674"
     CDS             complement(2454..2639)
                     /locus_tag="LLC22_000674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359862.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBK5433973.1"
                     /translation="MKTATRKDLINLGFSQYYANKIFKECKELLVEKGYFFYRNSKIK
                     RIPISILEEVLHISWEE"
     gene            complement(2993..3238)
                     /locus_tag="LLC22_000675"
     CDS             complement(2993..3238)
                     /locus_tag="LLC22_000675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5433974.1"
                     /translation="MVDKSKKRQYLLVPLSIILSALEGDPISIKMILKHYHSYMAKLC
                     LTNGFNEVGQFVTYVDEYMISQLEIKLIEAILKFKIN"
     gene            complement(3232..3633)
                     /locus_tag="LLC22_000676"
     CDS             complement(3232..3633)
                     /locus_tag="LLC22_000676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010818872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5433975.1"
                     /translation="MQQHYNDISIQHQFDAYCKKVLRNEAKSIRKRNANIKDNEEPLA
                     DSNEGRYSQTHFDEQDVYFLFGMEILISDQKLSAAIDQLSEIRRKIILLYYFAGFNDA
                     EIGKILNMSTSGIWYQRKKAVEQLKMGYDLW"
     gene            complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="LLC22_000677"
     CDS             complement(3818..5626)
                     /gene="uidA"
                     /locus_tag="LLC22_000677"
                     /EC_number="3.2.1.31"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-glucuronidase"
                     /protein_id="HBK5433976.1"
                     /translation="MLYPIMTETRQVIDLSGLWRFKLDTNDDLQEELALEPINEKESY
                     PISVPSSYNDLFETENIRNHVGWVWYEKEVTLPKRLLEERLVLRFGSATHEAKVFLNG
                     KLITQHKGGFTPFESEINRFVKDGNNRITVAVNNIIDDSTLPVGIMKETVQENGDIKK
                     ENLVNFDFFNYAGIHRPVKLYTTPKDYISDITINTRITDLDASVEFNIDTEWTGKILI
                     AIYDEEAQLVAEAEGKKGMIQLKNPIFWEPLDAYLYSMKISLIDDNKVIDTYTEEFGI
                     RSVQVTNGKFLINNKPFYFKGFGKHEDSYVNGRGLNEAVNIKDFNLMKWIGANSFRTS
                     HYPYSEEIMRLADREGIVVIDEVPAVGLHLNFMATLLDDNVEKHNTWKEIRTENSHKT
                     VIKELIERDKNHPSVVMWSIANEPDSDSEGAKEYFEPLVELTKELDPQKRPVTIVTYL
                     KSTPDICKVGDIVDVLCLNRYYGWYVSGGDLAHAKYLLKKELDGWKERCPDTPIMFTE
                     YGADTVAGFHDTVPTMFTEEYQVAYYEANHEVIDTCENFVGEQVWNFADFATSQGILR
                     VQGNKKGIFTRDRKPKMIAHYLQKRWSSIPNFSYKK"
     gene            complement(5649..7415)
                     /locus_tag="LLC22_000678"
     CDS             complement(5649..7415)
                     /locus_tag="LLC22_000678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003056564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-hexosaminidase"
                     /protein_id="HBK5433977.1"
                     /translation="MTIKVDLRKKPYNLDEDAISWIEETIDSMTLEEKIGQLFVNMGS
                     SRDKNYLSNMVNQYHIGAVRYNPGTADEVYDQNYILQTESKIPLLIAANTEAGGNGAC
                     TDGTEVGVEVKIGATNDAKYAYELGRVSGIEASAIGCNWSFAPIVDINRNWRNPIISS
                     RSFGQNPDKVLELSLAYMKGIQESGILPAAKHFPGDGIDERDQHLSFSINSLGTEEWD
                     NSFGKVYSGLIEAGLPSIMAGHIHMPAYSKHFNPDLKDEDLLPATLSKELITDLLRGK
                     LGFNGLVVTDASHMLGMTGAMKRSELLPTSIAAGCDLFLFFNDPDEDFNYMMEGYRKG
                     IISDDRLLDALKRILGLKAKLGLHKKAKEQILLPKQEALEKIGLIENKSIFKEVADQA
                     ITLVKDKQDIWPIEPEKYKRILLVDVHGVKGGFGEVVAGNRPQAIDLLKQILSAKGFE
                     VEKYISPEEELKGLSQEEKIKNIAGIYAAKRPIKNLTKKYDLIINIANVNPGTVQRIV
                     WPASKGTPDIPFYIHEIPTIFVSVQCPFHLADVPQVKTYINTYDGKQETLEILVDKLM
                     GLSEFKGVSPIDAYCGLKDTFI"
     gene            complement(7428..8222)
                     /locus_tag="LLC22_000679"
     CDS             complement(7428..8222)
                     /locus_tag="LLC22_000679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK5433978.1"
                     /translation="MNNWIFCIDSDGCVMDTMTYKHNLFFGPIAAEIFDVHHREKFLQ
                     DWNNINLYSETRGINRFLGLVKTLEKNDVTSINRLKHWVSLTKELSNPSLKREIEYYQ
                     SEDLLKALKWSEEVNQQISQAKGLDKPFLSARDTIKALKKYGKIIIVSSANKEAVQEE
                     WERHELLSLVDELCCQDKGKKEDIIRSVIENGCDLDKILMIGDSPGDLEAANKNKVFF
                     YPILVNKEKESWENLRTDVLFKCLSGEYVDIEQKFIDTFWKNLTNK"
     gene            complement(8232..9608)
                     /locus_tag="LLC22_000680"
     CDS             complement(8232..9608)
                     /locus_tag="LLC22_000680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5433979.1"
                     /translation="MERKFGIRDKIGYMFGDFGNDFTFIFASSFLMIFYTKVLGISGA
                     AVGTLFLVARFIDAVTDVTMGRIVDRSKATKQGKFKPWILRMSGPVALASFLMYQTSM
                     ISASMSVKVVYMYVTYILWGSIFYTSINIPYGSMASAITSITEERTMLSTFRNVGATL
                     ASLIIGVLTPLFIYTRDDSGAQIVRGGSTFTIVAGIFSICALICYLICYKLTTERVRI
                     DQSQFKVSLLKSLKGLVKNRALLSIIGAAIFLLLAQLLIMSMNNYVFPDYYNDAQGIV
                     LMNFINPILVLIVVSPLTLFLSKKYGKKELASVGMFFSAIVYLILFLIKTSNMYVFLI
                     LSSVGYMGLGVFNTVIWANITDVIDDQEVKSDQREDGTVYAVYSFARKIGQALAGGVG
                     GWTLSIIGYDSLANIQTGDVLEKLYNASTLIPSICFFIVGLILFFLYPLSKDKVLENC
                     ELLKQKYK"
     gene            complement(9728..10375)
                     /locus_tag="LLC22_000681"
     CDS             complement(9728..10375)
                     /locus_tag="LLC22_000681"
                     /EC_number="4.1.2.14"
                     /EC_number="4.1.3.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 2-keto-4-hydroxyglutarate
                     aldolase/2-keto-3-deoxy-6-phosphogluconate aldolase"
                     /protein_id="HBK5433980.1"
                     /translation="MKKVEILSKLEAAGVIAVVRGKNKDEAIKAINSIIAGGIKGIEL
                     TFTVPNAEEIIKEIAKKYADQKDVIIGAGTVLDAFTARIAIMAGAEYIVSPSFDRQTA
                     EICNLYQIPYLPGCMTITEIKEALTAGVDIIKLFPGSAFGPSIVKAYQAPLPHVNIMP
                     TGGVSLENLEDWFEVGVVAVGVGGNLLASVEKGDFEEVSRVASKYIDKFYEIKNY"
     gene            complement(10468..11895)
                     /gene="uxaC"
                     /locus_tag="LLC22_000682"
     CDS             complement(10468..11895)
                     /gene="uxaC"
                     /locus_tag="LLC22_000682"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBK5433981.1"
                     /translation="MFLDKNFLLENEIAKRLFHKFAKHQPIIDYHCHLDPAYLLENKQ
                     YKNLTQVWLNDKGAGDHYKWRLMRANGIEEELISGPGDDYEKFLAFVKTVEKAPGNPI
                     FEWSHLELQRYFDIDLTISEKNAPEIWRRANEKIQTDSYRPKELLEMMDVKAICTTDD
                     PTDDLGYHTELSKQDNSFKVLPTFRPDKVWSIKSSGFSNYILKLSQAAAIPIKDFNGL
                     KQALSQRVDHFHQIGCRLADHGLNTYFYEIADEKILDNLLIKALAGKTDFHLSEIAQF
                     VTGIQLHLMSEYTRYGWTMQMHLNALRNNSSILKEQIGVDVGGDSMGDQASLTQNVVA
                     LFDTAEKSGCLPKTILYSLNPTDWLPLATAMQSFQGGMIQKIQLGCAWWFNDTAEGMR
                     QQLTTMAQQSLLSNFTGMLTDSRSFLSYPRHEYFRRVLCQLLSEWVKAGRIPDDEMYL
                     SQIVENICYRNAYNYFNFFEIGSRK"
     gene            complement(11969..13048)
                     /gene="uxuA"
                     /locus_tag="LLC22_000683"
     CDS             complement(11969..13048)
                     /gene="uxuA"
                     /locus_tag="LLC22_000683"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBK5433982.1"
                     /translation="MEMTFRWYGANEEKISLQEIRQIPAMKGIVGTLMDIPAGEVWPR
                     ERIKSLKDEVEANGLTLKVIESVNVHDDIKIGLQTRDQYIENYKQTIRNLAEFGIEVI
                     CYNFMPVFDWVKSDLDYRLDDGSSTLAYISKNIPTDPEEIIRKVENSTNNFELPGWEP
                     HRLSQIKQLLEAYKEVDEEKLRENFAYFLKAIIPTCEEVGIKMAVHPDDPPYSIFGLP
                     RIVKNRDDLDWLCNVVDSPSNGITLCTGSIAERPDNDVYEILSEFCQRDRIPFAHVRN
                     IKYLSDNGLDFYEAPHKSEYGSLDMYKILKTMYDNGFNGYIRPDHGRMIWGETGRPGY
                     GLYDRALGAVYLNGIWEALEKGASK"
     gene            complement(13051..14682)
                     /locus_tag="LLC22_000684"
     CDS             complement(13051..14682)
                     /locus_tag="LLC22_000684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBK5433983.1"
                     /translation="MVSIKNWQNSIEEFNEMQILLPCFDVKEVKQEGQQHPVWLHFGG
                     GNLYRGFHAEIAQCLADQNELETGVVVCETFDEEVVEKAYHDYNNDILEIVMSGDGEL
                     KKRLLAVTADSLYCNPKNIADYQRVVKYFEDPKLQFTTFTITEKGYSLKDSKGQFFSV
                     VKADIKSGPSNPQHTMSIVTSLLYSRFNAGELPIAMVSTDNFSQNGQRFQDSIFTIAE
                     AWQKEGYVSEKFIAYLKDKEKVTFPWSMIDRITPNPSENVKEDLLMMGLEDLDIIHTK
                     KHTNIAAFTNTEVVHYLVIEDSFPNGRPKLEKAGVIMTDRETVDKADIMKVTTSLNPL
                     HTALAVTGCLLGYQSISAEMQDDDLVGLIKGIGYLEGLPVVENPGIIDPKQFIDEVIN
                     KRLPNPYIPDTPQRIATDTSQKVAIRYGETIKKYVEKDGNAENLTFIPIAIAAWLRYL
                     LAVDDQGENFVPSPDPLLVELQDKLSVLKLGEQDPSNIHCAVQEILENKEIFGLDLYQ
                     VGVGKKTEKIFCEMLVGPQAVRKTINKYITEVGGK"
     gene            14988..15659
                     /locus_tag="LLC22_000685"
     CDS             14988..15659
                     /locus_tag="LLC22_000685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5433984.1"
                     /translation="MTIKTSLQNQAYQSIRRQIIYADLEPGKKVSEKKLEETLSIGRT
                     PIREALIQLRQHGLVDTIPQSGNYISLIDLDSAKNARFVREHLERQIMLECCAKINNQ
                     KKRILETIISEQEKAVSQKNARSFFHNDNLFHKACFEIAEREEVWQWLENNNTHLERF
                     RWLRVKTEGLKWEKIMEQHYQLFEALTKQDPEEANFLTSLHLHLMLNEQNIVLATHPK
                     YFKSI"
     gene            complement(16362..16717)
                     /locus_tag="LLC22_000686"
                     /pseudo
     CDS             complement(16362..16717)
                     /locus_tag="LLC22_000686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313007.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(16734..16901)
                     /locus_tag="LLC22_000687"
     CDS             complement(16734..16901)
                     /locus_tag="LLC22_000687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002404637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433985.1"
                     /translation="MQTLINALQGKNYDYAVKILLDVAKRSLTPAQFAKFNAATIAAG
                     IAINAISCWGK"
     gene            complement(16901..17308)
                     /locus_tag="LLC22_000688"
     CDS             complement(16901..17308)
                     /locus_tag="LLC22_000688"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433986.1"
                     /translation="MSRFFKFFSLLGVMLIGLSTLVGAGTSVYAAEKVNEVPDIETQR
                     QQAVESLKFYLEEAGYVDTETHQYIVTDLEAIQKKAELDGSEGIAGKFILENFVQPTG
                     KRQKRDLQKYAACVVMNSLPFGVLFGIYLIVKI"
     gene            complement(17809..18003)
                     /locus_tag="LLC22_000689"
     CDS             complement(17809..18003)
                     /locus_tag="LLC22_000689"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433987.1"
                     /translation="MKDQKTNNKTGERSACSWAFTGAGLLHSGIYTAAALGLSLTGVG
                     AAVIPFAVGTAYGIAGAAIC"
     gene            complement(18017..18355)
                     /locus_tag="LLC22_000690"
     CDS             complement(18017..18355)
                     /locus_tag="LLC22_000690"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433988.1"
                     /translation="MKRIVKIFGILGVFLIGLSTFVSAGISVDASETNNFLVKQQETE
                     INIIQNNLATHKDSKGNRLVYIIDESDLKSSLDRINSEITVSEIQQYLNEFNRSIQKK
                     WPWMANRSAS"
     gene            complement(18399..18731)
                     /locus_tag="LLC22_000691"
     CDS             complement(18399..18731)
                     /locus_tag="LLC22_000691"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433989.1"
                     /translation="MSEEKKEIVESLVALKDSLSKIEYVDRKEIQKLIDDTIIEIQDA
                     RCEGIKISVALSKVIEKMNRSLAFNGLKLDRQTSLVWDHLKDLYDKSKRSERTAVSIL
                     KGLWGMNS"
     gene            complement(18745..19002)
                     /locus_tag="LLC22_000692"
     CDS             complement(18745..19002)
                     /locus_tag="LLC22_000692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003653123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433990.1"
                     /translation="MKKLIGYSVMCIGFVGVGLFVSTESASAAEWYNPIWYNPNIECQ
                     KVYPYGPTNLKNGKCRVNWNGVVDSVITGSMDSALHGFTGH"
     gene            complement(19197..19733)
                     /locus_tag="LLC22_000693"
     CDS             complement(19197..19733)
                     /locus_tag="LLC22_000693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433991.1"
                     /translation="MKKGIILVFSWLCLIGLTGCHWFSSEKQKTQLTTTEETIEAVKE
                     TSGTLQSTESNSQIGSLEDETAQQIDEMTKNFLKDFARKWSNFTDVYKRNQAVRDYMT
                     DRCIKDNSIDVDPHVQMKTTGKLHQVTQDIENPDQYLLFGEETTNEVTQFVLLQLKVD
                     QEAQKIDAIKIYYVRSVY"
     gene            complement(19754..20845)
                     /locus_tag="LLC22_000694"
     CDS             complement(19754..20845)
                     /locus_tag="LLC22_000694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK5433992.1"
                     /translation="MKKGCLGCLLFFILPFFLLPFFFSGELSEDGGEATGLAVAFNWE
                     YTEGLPIFSEIKGRGPITDEHAQAAVGAAVKYQLLPSVILSQLGYESTYGQSQSGRND
                     TNFFGITWFPGCPYPQGSARGIGGSEGGFYMKFPNLKDCYDYYGFLVASQSNFNQCVG
                     NKDPGSCLLILGRGGYAAAGITEGSPYYQGAMSIIKSYNLTEYDTFAIKHWNSLPTKK
                     SSLVAGKSKGNAKVLDRIIGRSVNNGECYGGTAWYVSQLGGPQLMGSGHMFAMLIGED
                     YDWTAYGWQVIMNPKPSDLQAGDVVNWQAGGALSPGIYGHTGIITDVSDGGQHFSSVE
                     QNAEQGRIMARYQRTYNQTKIRSLVRKVK"
     gene            complement(20853..23063)
                     /locus_tag="LLC22_000695"
     CDS             complement(20853..23063)
                     /locus_tag="LLC22_000695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433993.1"
                     /translation="MAYIKRKEKKWCVWLFLTVGFGLFFVGGLVYAVEKQVDQSIYEI
                     GKFHIDTFSSYLSDSEFSLGKMLFGANGTDFLKMMTNMFFSLSKLIWQGLDFVIEKLY
                     EGAAMNELIHQFFTFSDTIYSKIYDPIGAGIVVLYVLYLFTLRIFRGKHYAKMVFIRF
                     LFVVIFSMVWFGYGSNVPSKGEAFTKGLNDLSVEVEGFIFSATNSLDELATKDVNGVL
                     VPTTQKEAIQKVRQLYYKAAVVDPYLLLNYGTTNLEELYQAEIEPQEFLAKEASSEEL
                     SDIETKVTTAAGEDRGKKKAYRVYIQPTKAVYKAVVGSMVPLLNLSIGLPLVVIGMIR
                     FIFQMLVLCLLLVIPFSLLASFVPAFDYMIMNTLKSFLSLMFQKSFYSVIILVAFLIY
                     NIVDDLILMNTVFGFLGNMFVKALLSILLIVKRKDLLKKLGLGAADQTINNTKNIASH
                     SLSQMKQLPGQLSTAGQNLAIKGAGLAGNVYRATNPLASAAIHGFQKFQQKRTPQESV
                     KGGQVINPFELGGRSNQDLPYSGRHVRYHGVEPEMSSTKSKTEWNSGLSNGLIPNSSM
                     NSVRPKQQVQSLAQSSKQQGNNQRKPLLNKGIAFVGQSIPLPAGKVPVPQLTAAGSLS
                     QQIHQVKNQAKNGSYPAMQQLLNQYSVPKSSVATLSGNRSVQRQIQRSSESKPSISVP
                     KSLQPAFSSFNNPVEQSKKIEKKNETLPILDAKPGTDFTLPKGRTVQKPLSKKG"
     gene            complement(23079..25607)
                     /locus_tag="LLC22_000696"
     CDS             complement(23079..25607)
                     /locus_tag="LLC22_000696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5433994.1"
                     /translation="MVLVKEPVKALKKNCLLNGEDCIWAYYHVFPRTISKNTPKKTQE
                     IKEMMARLLLLLADYEDVELVMYPRTMNLRTKFDTLGKGFSPDSQAIGAYYAKETVTL
                     LEREGQVYRPSFILGIKVKEKATVESFYDVLNLIWLDVAGSLARLFGLEVDDLETLFS
                     ESDPYVKEVTQLLYSFSIRPLVKKELLYLNRLQYIRGMAHKVEEQNNWEVLKDNQGTY
                     VRMPKEHKGLLQLEDELGTSYLALLPIGETPENMRNCDLFQFAQDLSFPAELRMKIHY
                     PRLKGQGGIGLKLNWLSERFKTEYKELVQNDEEPSERLLTVRGLVKHLKQRVDNGQPV
                     VDWIACFIVYGQTVEEVRQNSATIIQQLHTTIHIHRAKNDQRELFYKCLLGQPLGRQL
                     HWKHRTTVEAIGEWLFSAVSELGMESGWYIGRQDTLGDGGSRGEKTPLEELIYASNRF
                     VFLNLLAIAEGIKGALFDAPHVAVTGKTGKGKTFLVGLLFLYSSFMNVQSLFVDPKGE
                     KRKWFTKLIQDPYYQKHYPLFVEHLQKMSYVTLDATNPRNYGVLDPIVCLSRVDAKQV
                     AQDMIDELSPLGTNHLLKGAVLKGIQEVLVQKEAGQQVGLMHVVEYLEQMEQKEVREY
                     GEFLRLTVEDSILRLGFSYGENPGLDFNAKTTILEIQDLKLPNDNVRPELYTDADRKS
                     LCLMISLGRFCEMFGKRDSSKKTAIYFTEAWVFNNSNAGRSIIAAMARVGRSQMNQLV
                     LDTQFIGDLGSDKEKGNFGVVFAFDEDSEREKILTHLRLEVNEANLSEMSHMIKGQCW
                     MLDPYGRVGKLNVHSLFEEMTAALQTTEKTSHSQIEEQDTLIMQ"
     gene            complement(25661..26071)
                     /locus_tag="LLC22_000697"
     CDS             complement(25661..26071)
                     /locus_tag="LLC22_000697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433995.1"
                     /translation="MDWEPYDYSIVYAEPYRVQQITSNWRLPFPVALVNAATFLLVVI
                     FEYLFLRSFIGWVISFFPPAGVVFFIGLPYLCVLALAKLKPDGKKVHFYLWDWFCYVV
                     RMMNGDCVYYNWDKVSNNALEELLFANKYVYLED"
     gene            complement(26084..26302)
                     /locus_tag="LLC22_000698"
     CDS             complement(26084..26302)
                     /locus_tag="LLC22_000698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433996.1"
                     /translation="MTLKGIVDFILTQGGYFLIMVVVYLGLRNFMKSKVGNALISIAA
                     GAAVYFFLNDPTRVFDAFGKIIEKLFMD"
     gene            complement(26299..27291)
                     /locus_tag="LLC22_000699"
     CDS             complement(26299..27291)
                     /locus_tag="LLC22_000699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5433997.1"
                     /translation="MKKRQLRRKEKVYTEKVPNQRKIHSKKAVKWIWCLVLFLCFSGG
                     LAFFQSMKTKVQVSFLKDEIQQLQKKEVQSQSELTYTPEIESFMNRFVALYMNTFDNH
                     EQEQQRQEILKKEFYAQNFIQEPGSVSGIRKLTAASFIGLKEIETIPTASYKVTYDIR
                     SMDPENKKETSVTITQVLNLPFSISNKGCRIIAYPYFTALPKNTEKQRMITYDDTLYE
                     TVDASEAKDVEGFVEDFLDKYAKNNAKDMSYMMKEPEGLNQTAKVDQVEMKVLRYKET
                     KKTFIVKATVVFRDGDTSLLQKEQMTLVITKKTNQYYVEKLTHNWLDRKGDERK"
     gene            complement(27370..28281)
                     /locus_tag="LLC22_000700"
     CDS             complement(27370..28281)
                     /locus_tag="LLC22_000700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5433998.1"
                     /translation="MKKTTLAVVTTLGISLFSFQLGSSLVYADETVETPKSEIVETLP
                     GEGLSDVETELNGGTTEKPAEPEHLQPEKPEKEPVAPEPEIPESTLPTDPIEEEGVHS
                     STTTDSSIVTTPEQSGTTSSSETNTDSSSTEQPTMSFTSEEPKEEPKQPAEKSEAIPK
                     ENKPIVPAKEVTVSVTPNGEITTNNSQGMSVPIVTSNVEELTHIPTPTTPLKAEGGQT
                     IVGVKDGIPLIQDSEGNLVKDLSIPVKKLPSGNIEVKTADGKTKVLPKTGEEIHVVLS
                     VLGGVLTSIAGFVGYKRKRKGIENEGN"
     gene            complement(28300..28644)
                     /locus_tag="LLC22_000701"
     CDS             complement(28300..28644)
                     /locus_tag="LLC22_000701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5433999.1"
                     /translation="MWRLLFLVVCGMALFYVYRVYLGPRTERWTSWYRDPLKQRKGLK
                     RYRYELLVEFSDGRQAQYYFFANYPKYNTSELLIQLFKNNPYVGLEENGREFFYRSDN
                     ISAASMNKTRIA"
     gene            complement(28664..29221)
                     /locus_tag="LLC22_000702"
     CDS             complement(28664..29221)
                     /locus_tag="LLC22_000702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434000.1"
                     /translation="MSLEFLGEPIEKEEFVSHYMDLFIRVIKKLCTIDEFYPREQDYL
                     AAERIKISLLWEKFTDENNRPPDYRYLSDCLTNNVLSKEYLFHKREKNQMSAEHFCDC
                     YIALLRSQQLLTVERYGAEFGYVMQAERHRATRCYEKEDQVIDGYEELCIRNNRYLQQ
                     RLYEKLMMDFSDLYRGYECSVIQER"
     gene            complement(29301..29801)
                     /locus_tag="LLC22_000703"
     CDS             complement(29301..29801)
                     /locus_tag="LLC22_000703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434001.1"
                     /translation="MKKIMIYVGAYWSRDPTVLENPEAVHYCLRQLFYLYKERLESLI
                     RQLPYTDRRLDELLLRYPAMYKRRKNRLLPKEYPIEKRELEGRFVAYFYDDVRMRLVE
                     QRMEIENDRYYFINYCKKRKYQVTDDFYDCILQDGEVILSKIAPSFRELVPINFLKKC
                     HLRILP"
     gene            complement(29802..30347)
                     /locus_tag="LLC22_000704"
     CDS             complement(29802..30347)
                     /locus_tag="LLC22_000704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434002.1"
                     /translation="MNAYTTTEWLRLLDLKAAIEALNEKMVDLSYFRFRVPYIEQAVK
                     AGRYQEKENWQEIARLLEVRKGYEQELEELEFSRRKGTLKFIRFYRFSLPVPAILAVK
                     KGCDKMKIYENCVAALSNEKPLVEEISLATVTWEMNRQPTEEQTYLSLEEIELELEEI
                     GRYATCSTYCGSVISIAGVIV"
     gene            complement(30344..31600)
                     /locus_tag="LLC22_000705"
     CDS             complement(30344..31600)
                     /locus_tag="LLC22_000705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5434003.1"
                     /translation="MTPIELRNYRKKLSAIHASGGGKKLLSQKRFAQLLGCSVDYIKK
                     MEQGKKKIPEDFEKRIKERFRLYMKSGIDLRAMIDYLRLSFFGTDYKIVIQRVLRMDL
                     TEFETRPTGLYLFDCLSVRGNIWVFWHSKQTVTQNVLVQFSGQGCREYEEVMREQRTD
                     WRTWLYSIWKNQGKLEAGYKRVQCSRFDIALDELWGLETEEHFDLFELLEKQKAGLLE
                     MDFKKFQNIGGCFLDDGYFRSEGLSLYFGSRKSPLFFNFYEKRFEIANREKISEIEAL
                     TKYGIYNRYELRLANEKATQAVEAFILDHSPKRLGEIGVGLINAKLIVWDRLESDARI
                     VDERWAKLFRSMEELDFTVKPEKFSLDRSERWFLKQVAPTLKLLQEADRILGRDFVQE
                     GIENAELNDEQQSYLEWMGTSGGKIA"
     gene            complement(31963..32277)
                     /locus_tag="LLC22_000706"
     CDS             complement(31963..32277)
                     /locus_tag="LLC22_000706"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434004.1"
                     /translation="MGEVLYRVSSAAGEISPDFAVRRLYEWINKVEYYTKGSYVFRRI
                     ERETLFVTRNQIVLTKEDILRFRQVYRLCKEKNIQLRLAILQCFAPEQYKELQEKEDS
                     LV"
     gene            complement(32404..33597)
                     /locus_tag="LLC22_000707"
                     /pseudo
     CDS             complement(32404..33597)
                     /locus_tag="LLC22_000707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322060.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cell division protein FtsK"
     gene            complement(33787..34143)
                     /locus_tag="LLC22_000708"
     CDS             complement(33787..34143)
                     /locus_tag="LLC22_000708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434005.1"
                     /translation="MNLDKTNQTLREIMVCCQNIQQLIEYFGDNPTIFIQTNEYICAV
                     IGQCMFLRDLVRFSLPYQWKQDHQEVVWIRVVRICNMCAHPYKNRLNLFRLWFFIKCD
                     IPVLVAFCQKFLAQEK"
     gene            complement(34209..34661)
                     /locus_tag="LLC22_000709"
     CDS             complement(34209..34661)
                     /locus_tag="LLC22_000709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434006.1"
                     /translation="MGLKFPNNYDITEALDETCIGAVRFGALEESDRVFDNETGDYTG
                     EIRSQRAQLVFGNPDEPKIARRVKFPADVDLTGFKRRDPVKLIDPEYHVVYIPAQDGN
                     REYSDLVIYAKGLEKVEAPTNNSNPKQSQEKGLDQKQPSADSKEKEKK"
     gene            complement(34663..35028)
                     /locus_tag="LLC22_000710"
     CDS             complement(34663..35028)
                     /locus_tag="LLC22_000710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434007.1"
                     /translation="MAEKALRMKKEFLGQVFLLGSREPNPPKEINGVSGRYVQLQAEC
                     SREEQPAFFVYLTAEEDKRLRLPEKEVRISFEEAYFVFRKERVNSRETNDMGQTERRT
                     TGYQDVGVFLTGVKIEEVL"
     gene            complement(35045..35299)
                     /locus_tag="LLC22_000711"
     CDS             complement(35045..35299)
                     /locus_tag="LLC22_000711"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434008.1"
                     /translation="MEKELLLGFYRKENNGGKKNMEKKNINICFLSGKECTYEECTDI
                     SVHERDGMLIVDMSPSDEPFVVKHYFPLCNIESFRIDCEF"
     gene            complement(36217..40512)
                     /locus_tag="LLC22_000712"
     CDS             complement(36217..40512)
                     /locus_tag="LLC22_000712"
                     /inference="COORDINATES: protein
                     motif:HMM:NF019941.1,HMM:NF037291.1,HMM:NF037639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VaFE repeat-containing surface-anchored protein"
                     /protein_id="HBK5434009.1"
                     /translation="MYAKTKMNWLKALALVALSQFCFLVGTAQAHAEETTATQPTVEA
                     IAQVASEVTEVQPAEAGVPAGEATVEQAPVTEAPTVNSKTTLDQTIGETQHPGNSPVT
                     SQPVEETASITTPASETSTPEGEKAAEATPSVKPESSEKQAEEKQRIEETVEQPAATA
                     DKEGKNEENVEKTISSTAASQNQPTKLNKESTASIEDQKKKEQDIPKTGTPTLLVTVP
                     TNRSVRVRRATNTAVLGGRKIDWGENIGVTSSPNNPNFTLNYMVRFEINGQVAFCIEP
                     GVSAAEGQVYTATALENYLKNSNVRKKTSLISYLGYVTNKDKSDEQYIAAQFMIWEAL
                     GTKIPIKNIRVDYDRRKAEIQRLLNNFDVRATFHNQTHTIKIGETLKVKSGNDFLQRV
                     KGIQKPKGINVSIHGNEAWITVTKEAPEKAKIHFNQIEVLGTPLAYRRPGAQTIGILN
                     PFEPGDSVVNLTILKQGNIRVFKEDAETGVKAQGAASLENAVYGLYQADGKKIKEITL
                     KNMNGKVQAEIKDLDPGKYVLKEIKAPKGYALSDETIEIVVEPGKTVNATAKDQVIKG
                     TIDLVKIANKDLVDSTNPDNKPKLAGIEISLTSKTTGKVVKTVVTDNDGYATFGKNTV
                     VFDTYILSETKGKEGYKLFEPLEVTISENGQTFHYVLEDKVIEQRLKVVKVDQETGKV
                     IPLANTEFKIFDTLANRYVTMEIPNDTETTDIFKTNEKGFFLTNGTLTYGKERYRLEE
                     IKAPVNYVLNQNPLVFSITNDTEPIKVIHFANRQARKSVKLFKYEEWNKKKTPLAGVT
                     FTLYNGKGQAIGKYTTDQNGEILVKGLVANNYYFTENVPLESFQPNTGKQAFTITFRQ
                     NAPDDGETLLVSVRNYLIPPKLETQASNKADGEKVVDPLETIVIKDSVSYTNLFVGKE
                     YTISGVLMNKATNAPILQEGKEITSILTFIADKANGTKDLEFVVNASVLKGQTIVVFE
                     KLFRDGIEVAVHVDINDDNQSVRVNNPTVHTTAVFEDGLTIADPTGLFTLNDTVEINE
                     ILPGKAYLVKGILMDKATGEALLVHGQPVESAVGFIAKAENETVIVPFTFDLTGLNGR
                     EMVVFESLFRNDEELANHKDINDKGQTVRVTNPSVRTTATHKPTGLKEVNPLTKVTIT
                     DAVKYHDLIVGKTYTVNGVLMDKVTEKPVLVDGKEVSSTLTFVAETTDGTVNLDFILD
                     AHALRSKEVVVFEDLFREGVLLASHADITDKDQTIKIVSPTITTKATNANGGKEILAL
                     PNQKVVEWVQVNGLAIGQIYKLIVQGYLTPDGTPFEGTHAEKVFMADKEMMEFLFEFI
                     VDGRNLAGKGLSFAEWLQAKTEDEKETFEEVAKHNVDLTNKDQTVQFVEAPKPPQPVK
                     PNEPQPVKEVKQAAMVPMLPKTGSEDNVLWIMIGMIFVLAAGLIGYDLYKVRD"
     gene            complement(40659..40898)
                     /locus_tag="LLC22_000713"
     CDS             complement(40659..40898)
                     /locus_tag="LLC22_000713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434010.1"
                     /translation="MIDISIPEDLKPDPATIGNSGMIFDSLDEAMSYGWKEIKDEGSN
                     WYGMIFGDGEVANKAGIPIGKWTVDFHEAGSFFVL"
     gene            complement(40988..41260)
                     /locus_tag="LLC22_000714"
     CDS             complement(40988..41260)
                     /locus_tag="LLC22_000714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434011.1"
                     /translation="MSDGFEQVSIIKNQVREILRKKGYLVDSYFEGDYETWVGVYARP
                     ENKPTYLDPTTSEDAYLQNRYRVDGFKQDFAEWFEWEIENGEVKEE"
     gene            complement(41343..41594)
                     /locus_tag="LLC22_000715"
     CDS             complement(41343..41594)
                     /locus_tag="LLC22_000715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434012.1"
                     /translation="MRKVLVFNTRGQSFLGIEGTRVTVDGWCDCFEVGKHVELMAFTE
                     LKDKNNVEFVESDIGWDDHEEVYGKFILRKGNSYTNGEA"
     gene            complement(42592..43503)
                     /locus_tag="LLC22_000716"
     CDS             complement(42592..43503)
                     /locus_tag="LLC22_000716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434013.1"
                     /translation="MVDNSSGRVLKSLRKEKKLSQKKLADLAGISQSTLVKYEKGSRK
                     IPKDVDNTLSKILNIETLIKDEEDKIEILIGQLIAYRDMNKLLNKELADNIGISEVLL
                     SYVLNRKRNPSKEMQKKIDIFLLSNEKEISKESNRDSEIFSLSKDDKIVMGKRIREVR
                     KNREETLEKFGKNFTIYTGKNVISRWEKGINIPDIEKLMNIAYLGKVTVPYLMYGEDY
                     KNILPKDERVSDFNKINSFSMGLRMRKIRKDYYLEREEFGKLFSPSISKWSIDRYENG
                     RDIPNTNRIIQYAYIGNLSLEFLIYGI"
     gene            complement(43700..45535)
                     /gene="lepA"
                     /locus_tag="LLC22_000717"
     CDS             complement(43700..45535)
                     /gene="lepA"
                     /locus_tag="LLC22_000717"
                     /EC_number="3.6.5.n1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor 4"
                     /protein_id="HBK5434014.1"
                     /translation="MDIKKMKERQEQIRNFSIIAHIDHGKSTLADRILEMTHTVTSRE
                     MQDQLLDSMDLERERGITIKLNAVELNYTAKNGETYIFHLIDTPGHVDFTYEVSRSLA
                     ACEGAVLVVDAAQGIEAQTLANVYLALDNDLEILPVINKIDLPAADPERVRQEIEDVI
                     GIDASEAVLASAKSGIGIEDILEQIVEYVPAPSGDLDAPLKALIFDSIYDSYRGVVLN
                     VRITDGMVKPGDKIKLMSNGKTFDVTEVGVFSPKAVARDFLMVGDVGYITASIKTVQD
                     TRVGDTVTLADNPAAEALPGYRKMNPMVYCGLYPIDTSRYNDLREALEKLQLNDAALQ
                     FEPETSQALGFGFRCGFLGLLHMDVVQERLEREFNLELITTAPSVIYHVNKTDGTTAT
                     VDNPADFPEPVTIQDVEEPFVKAQIMVPNDFVGAVMELSQRKRGEFITMDYLDDYRVN
                     VVYNIPLSEIVFDFFDKLKSSTKGYASLDYEMSGYQKSKLVKMDILLNGEKVDALSFI
                     VHRDFAYERGKAIVEKLKKLIPRQQFEVPIQAAIGQKIVARSDIKALRKNVLAKCYGG
                     DVSRKRKLLEKQKEGKKRMKQIGSVEVPQEAFMAVLKMDEQDSVK"
     gene            45682..46902
                     /locus_tag="LLC22_000718"
     CDS             45682..46902
                     /locus_tag="LLC22_000718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434015.1"
                     /translation="MDQKDFRENLELKPVTQEHIDQFNELLSYVFQVTEADIEESGFE
                     NKRAFIRSKKPILEVSKVFGWFHENKLISQIAIYPCEVNIHGARYKMGGVTGVGTYPE
                     YANHGLMQDLIIVALDNMRKNKQWISYLYPYSIPYYRRKGWEIMSDKLSFKIRDTQLP
                     KQIPVSGMVERLPVDHPDVFSVYDKFAQQNHGALFRSDFHWEEYWRFENEDERTAAVY
                     YDSNHEPRGVLFYWVAEEIFHVKEMFYLDQEARNGLWNFISAHFSMIYWVHGDIYKNE
                     PLAFLIEDSQIKEQIEPYFMARIVDVKEFLQRFPFVGTADAFHFIIEDPVAPWNNGVF
                     ALTWDEQGQVRVLNEPIGKSVRLDIQTLTCLMMNYRRASYLARIERLETDEETLKSLE
                     RIIPNMEAYFSDYF"
     gene            46922..47416
                     /locus_tag="LLC22_000719"
     CDS             46922..47416
                     /locus_tag="LLC22_000719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBK5434016.1"
                     /translation="MKIYFAAPMFAKSDLLYNQQLVKEIRELSSELSIYLPQENEAIN
                     DKTAYADSRMIALADTEKVLASDLMIALLDGLTIDAGVASEIGVAYAKGIPVIGLYTD
                     TRQQGGTHPKKIAALQETAENQFHYLNLYTIGLIKLNGKVVSSEIELLSEVKRFLDGG
                     TFSD"
     gene            47394..48080
                     /locus_tag="LLC22_000720"
     CDS             47394..48080
                     /locus_tag="LLC22_000720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434017.1"
                     /translation="MEGLSVIKEIKKVQIALLAFGVFVVCYNFYEFITQKYSTSQGIT
                     FIVESLLGIALIFMPQVILKVFKLKIPAAIVLFYWFFLFISVFLGTGMHLISIISFWD
                     KILHAVSPMVLTALGYGLIGYLMKDAEISKTSPWLFLLFGFAFAGLCGVFWEFWEFLC
                     DQFLGMNLQRFAASDGTLFVGRAALMDTMGDLLTNTIGAALMGLFAWSQSKKDERYFE
                     SYKLEKVKNT"
     gene            complement(48231..50840)
                     /gene="clpB"
                     /locus_tag="LLC22_000721"
     CDS             complement(48231..50840)
                     /gene="clpB"
                     /locus_tag="LLC22_000721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent chaperone ClpB"
                     /protein_id="HBK5434018.1"
                     /translation="MNIEKMTTTLQEAIAEAQQIAVTRKHQDIDIAHVWKIFLQPNHF
                     GRNFYTDAGLDVESFEHEIDRLLDEYPVVSGGNVQYGQNLSQNFFRLLNEADQIRESF
                     GDEFLSTEVVILALMKLKNYPLTVYLNKNGLSEKELRKNIEEMRGGERVTSQNQEEQY
                     KALEKYGVDLVQQVKSGKMDPIIGRDEEIRDVIRILSRKTKNNPVLIGEPGVGKTAIV
                     EGLAQRIVRKDVPENLKDKTIFSLDMGALIAGAKFRGEFEERLKAVLKEVKKSDGRIL
                     LFIDEIHNIVGAGKTEGSMDAGNLLKPMLARGELHLIGATTLDEYRQYMEKDKALERR
                     FQKVLVKEPTVEDTISILRGLKERFEIHHGVNIHDNALVAAATLSDRYITDRFLPDKA
                     IDLIDEASATIRVEMNSMPTELDQVTRRLMQLEIEEAALKKESDDASKKRLKNLQEEL
                     AELREEANAMKMQWETEKEEVNSVSAKRAEIDKAKHELEDAENNYDLERAAVLRHGTI
                     PQLEKELKELEAKAKDSEIKMVQESVTENEIAQVVGRLTGIPVTKLVEGEREKLIKLN
                     ETLHKRVIGQDEAVDAVSDAVIRSRAGLQDPNRPLGSFLFLGPTGVGKTELAKALAEN
                     LFDSEDHMVRIDMSEYMEKHAVSRLVGAPPGYVGYEEGGQLTEAVRRNPYTIVLLDEI
                     EKAHPDVFNILLQVLDDGRLTDSKGRVVDFKNTVLIMTSNIGSQLLLEGVTADGTIPE
                     AVAEQVNTLLRGNFKPEFLNRIDDTILFTPLSLDNVKGIVDKMVAQLAQRLEHQEILL
                     TISDEAKTWIAENAYEPAYGARPLKRFITKEVETPLAKEIVAGHVMPKSKVTITLLDG
                     QLHFKTEELEEIV"
     gene            complement(51091..52137)
                     /locus_tag="LLC22_000722"
     CDS             complement(51091..52137)
                     /locus_tag="LLC22_000722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flippase-like domain-containing protein"
                     /protein_id="HBK5434019.1"
                     /translation="MSSKGTKTKIILNLLLLIVIFAIIYYLINQSFADIFAELLSTSV
                     VVLAAAVILGTVYQIAEGRSIKEIAEPFAPNFTTKDGFLTSSYIAFYRIVSFGTGTLI
                     SEIYFYNKKGMKLSQGAGVTALHMIMYKLAVITYALAGLVIQFSLFYSNGPSMIWFII
                     AGILLTIVIVAFLLAMSVSLNVQIFFVSLSNKLFKSERLRKWVDTCNQQIYSLRETVQ
                     TIIQDRTALLRIYLWNMLKLVFWYVLPYLILIENHPKIDFLLTISFISFAVVLSGVIP
                     TPAGIGSFEFVYLLLFRPVVGTVDAVSSLLLYRFSSFILPFLYGFVYVIAERRRVIKE
                     EIIEVKKENKENQG"
     gene            complement(52148..52420)
                     /locus_tag="LLC22_000723"
     CDS             complement(52148..52420)
                     /locus_tag="LLC22_000723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305633.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1294 domain-containing protein"
                     /protein_id="HBK5434020.1"
                     /translation="MDVLLHNLLWFYLFIVNFYLFCLMGYDKHQARTSGWRVPENNLI
                     FVSLLGGGLGGLISRKVFHHKTRKKKFTIGFAAGVLVDLILIYFFH"
     gene            complement(52455..53363)
                     /locus_tag="LLC22_000724"
     CDS             complement(52455..53363)
                     /locus_tag="LLC22_000724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YegS/Rv2252/BmrU family lipid kinase"
                     /protein_id="HBK5434021.1"
                     /translation="MEKLLVFYNKSSGKDEGEKLARWFQDYVKEKQPELYVELAETGP
                     SIDDAELVKKAEAIEADTLVIIGGDGTIHHIVQAFQKTLSQYHVGLLPGGTVNNLARV
                     LEIPLKKEEAADVILEGNVRKIDYGQVNDEVIISTLTIGILADTAVWISQEEKQRYGS
                     WIFIKKFFKLLLKKKKYHLDLETDEEHWKGKSQLLTVTMSNSVGGFTNFDDSATLDDG
                     KFHVTIVPSLDIFRFIFYLPRIMRGKFYTIPGITYFTAKRMKIQAQEKSVGTRTDGDT
                     TDDLPVELSVVSKGLTVYSPKKEEKA"
     gene            complement(53495..54727)
                     /gene="pepT"
                     /locus_tag="LLC22_000725"
     CDS             complement(53495..54727)
                     /gene="pepT"
                     /locus_tag="LLC22_000725"
                     /EC_number="3.4.11.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase T"
                     /protein_id="HBK5434022.1"
                     /translation="MYENLLPRFLRYVKTETRSDATSKTTPSTQTQVAFAQELKKELE
                     ELGLADVFYNEDNGFVMGTLPSNVDHEVRSIGFISHMDTADFNAVGVNPQIIENYDGE
                     STIVLDAEERYTLNTKDFPNLKNYEGHTLITTDGSTLLGADDKSGIAEIMTAMEILIN
                     NPSIPHGTIKVAFGPDEEIGVGADKFDVEQFDVDFAYTVDGGPLGELQYETFSAAQAN
                     ITIQGKNVHPGTAKDTMINALQLAIDFHNQLPADEVPEKTEGYEGFFHLMALDGNPEE
                     ASMSYIIRDHDREKFEARKAQITHIQEELNQRFDQERIKVDMYDQYYNMKEIIEKDMS
                     IVELAKQAMIELGISPVIEPVRGGTDGSKISYMGIPTPNLFAGGENMHGRFEFVSLQV
                     MEKATDVIVKIAELNTKS"
     gene            complement(54742..55863)
                     /locus_tag="LLC22_000726"
     CDS             complement(54742..55863)
                     /locus_tag="LLC22_000726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nif3-like dinuclear metal center hexameric
                     protein"
                     /protein_id="HBK5434023.1"
                     /translation="MTISGRTFIQKFESYCPQWLAEEGDPVGLHIGTLDKPIQRVMMT
                     LDVRPEVVEEAIKKKIDLLIAKHPPIFRPVKRLVTDQPQEKMYADLLKHDIAVYAAHT
                     NMDIIWDGLNDWFCELLGIEVESYLVKTHEIHYKKLAVYVPVDHAQKMREVLAAAGAG
                     TQGDYTGTSFTSIGHGRFTPEAGAQPAIGKVGKTEQVQEAKVEVILPETIEKQVIQAM
                     RSAHPYEEPAYDLFAIDEPVEMFGLGRVGELPQEISIEAFVEQVKEAFQLDGLRIVQP
                     KNAKSSVKRIAICGGSGEKFYPQAIAQRADVYITGDIYYHTAHDMQSAGLIAIDPGHY
                     IESLCKQRFIEKFESWKQEENWDINFFVSETNTNPFQFN"
     gene            complement(55860..56561)
                     /locus_tag="LLC22_000727"
     CDS             complement(55860..56561)
                     /locus_tag="LLC22_000727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenine-N(1))-methyltransferase"
                     /protein_id="HBK5434024.1"
                     /translation="MNHLDLSQRLAAVGDFVPESARLADIGSDHAYLPVALILRGKIE
                     YAVAGEVVQGPYESARKQVKKDGLEDRITVRLANGLDAIQPQDGITAVTIAGMGGSLI
                     RDILEAGKLNQRLSGQERLILQPNIGERTLRSWLQENQYKIQSEKILEENKKIYEIIV
                     AEKEQKPVTYNEMELMFGPFLLEEKSEIFKSKWTRELQQRKAIREQLKQAANQEARQK
                     QIEQEIQMIEEVLKP"
     gene            complement(56705..57145)
                     /locus_tag="LLC22_000728"
     CDS             complement(56705..57145)
                     /locus_tag="LLC22_000728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK5434025.1"
                     /translation="MRAIFSSISVVGLFFLLAGCGSADSNTGSVDSIDAGQTVKTSST
                     KTERQSIFVGTIESITQVEAEEETLQLKLVDVMAKEDPANMGTSFSNDGVILNATAEK
                     ISVDINELKIGDKVQFTLVEMPIMTMSIPPQVPGDSIIDVSLNK"
     gene            complement(57274..58200)
                     /gene="dnaI"
                     /locus_tag="LLC22_000729"
     CDS             complement(57274..58200)
                     /gene="dnaI"
                     /locus_tag="LLC22_000729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein DnaI"
                     /protein_id="HBK5434026.1"
                     /translation="MEDVGKELKRIISKRNYQEKYAEMIAEVLNDADVQAFLSAHQEE
                     LTQADIEKSYAKLYEFVQEKRKYQKNDPTMIAPGYEPKLTLNFHYVDVTYVPTEALLA
                     RQRQEEIRSRVKAMDMPKDIQSASFENFERTDGRGYASLEALDFVEKYTADPKGYHKG
                     LYLVGSFGIGKTYLLGATARELAIAGFTTTLVHFPTFAVEMKQAIGKDQVAEKLDAVK
                     RSPILMIDDIGADAMSSWIRDEVFGVILQYRMQEQLPTFFSSNFTMDELEQHLSVTQR
                     GDEEPLKAKRIMERIRYLTKEIEMTGRNRRNG"
     gene            complement(58200..59573)
                     /locus_tag="LLC22_000730"
     CDS             complement(58200..59573)
                     /locus_tag="LLC22_000730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DnaD domain protein"
                     /protein_id="HBK5434027.1"
                     /translation="MENAWKELQPKNIYQGRKAAPLREDSKNALLYLYQPLIGGEALS
                     IYFTLLSEISQESGKGPEGMHADLLSSLGCGIPQFYDARKKLEGIGLLDVYFKEDSDL
                     GPRFIYELLEPLIPKAFFKDSVLAFLLLEKVGERRFQKLTQFFEPKRHTAEGYQKITK
                     KFLDVYRFNEAVYAANQENIESLNKSFEESESVALLEADSTFDWQFLNDWLAKKHIAS
                     LDDPIIKQVDMYHQLYGFDELTLGELISQSYDFSEQKVSEKELQKAILAMQRRPVKQT
                     KETVAVSENSNEPSSNEHLTNAALQLIKEAQSIPPMKYLEAIKSEKGGYVSKQENWLL
                     QDLVSQSGLSSSVINVLLNYVLVIKNNASLNASYVNTVANEWAQKKIATAEEAIQHIR
                     QISNQAKQSKQKKQTNYQTGKRNVRREKLPDWVNQPKDEKQISSEKKAEIDRRFKEYL
                     AKKEGDI"
     gene            complement(59596..60087)
                     /gene="nrdR"
                     /locus_tag="LLC22_000731"
     CDS             complement(59596..60087)
                     /gene="nrdR"
                     /locus_tag="LLC22_000731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor NrdR"
                     /protein_id="HBK5434028.1"
                     /translation="MRCPRCQHNNSRVIDSRQADDGRAIRRRRECENCSFRFTTFERI
                     EAAPLLVIKKNGEREEFNRDKILRGLIRSAEKRPVAMEQMEQIVNHVENRVRSLGENE
                     VSTNLIGEYVMEDLVDLDEIAYIRFASVYRQFKDMSVFLKELQDIVDKAKENNKENNK
                     ENN"
     gene            complement(60399..60731)
                     /locus_tag="LLC22_000732"
     CDS             complement(60399..60731)
                     /locus_tag="LLC22_000732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBK5434029.1"
                     /translation="MGSLKNQKDKVVGNAKEKIGEMLNKENLIDEGRTQSETAEEKEK
                     QYQARIDEIEDQQAEEEAKRQDLTQERKNPTPDRSKTPLPESDHISDEQKIEEQRMKH
                     YTGIEEKL"
     gene            complement(60783..61412)
                     /locus_tag="LLC22_000733"
     CDS             complement(60783..61412)
                     /locus_tag="LLC22_000733"
                     /EC_number="2.7.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dephospho-CoA kinase"
                     /protein_id="HBK5434030.1"
                     /translation="MSELSKAKNRKVGFVLGLTGGIATGKSTAAKVFQSHGFPLIDGD
                     VIARETVEPGTLALRKIVSVFGQEVLQPDGQLDRGKLGMIVFPSKEKRQKLDQLLDPF
                     IRKAIKDQIASLSSNHPLVIVDIPLLYEGHYDHYMDAVAVVYTTPETQLQRLMKRNQL
                     TLEQAQQRISSQLPIEEKKQRADILFDNNGTKEKLVGQIENWLFANRFL"
     gene            complement(61376..62212)
                     /gene="mutM"
                     /locus_tag="LLC22_000734"
     CDS             complement(61376..62212)
                     /gene="mutM"
                     /locus_tag="LLC22_000734"
                     /EC_number="3.2.2.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-formamidopyrimidine glycosylase"
                     /protein_id="HBK5434031.1"
                     /translation="MPELPEVETVRKGLERLVVGKTIQKVQVLWPKIIEQPETPIFEA
                     SLVGETIQSIGRRGKFLIFHLDHCELISHLRMEGKYQFTKENTPIDKHTHVLFFFEDG
                     SQLRYNDVRKFGRMTIVEKGASATYRGIMKLGPEPLPDSFLLADFANGLKKSHKAIKP
                     LLLDQRLVTGLGNIYVDEALWEAKIHPEQPANTLRPKEVEQLRLSIIDVLDRAIEAGG
                     TTIRSYLNALGESGGFQVALHVYQQTGKPCIRCGTPIVKTKVAQRGTHYCPNCQRLKI
                     AK"
     gene            complement(62257..64902)
                     /gene="polA"
                     /locus_tag="LLC22_000735"
     CDS             complement(62257..64902)
                     /gene="polA"
                     /locus_tag="LLC22_000735"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase I"
                     /protein_id="HBK5434032.1"
                     /translation="MTKNKLLLVDGNSVAFRAFFALHNSLERFKNRNGLHTNAIYAFN
                     TMFENVMQKEQPTHVLVAFDAGKTTFRTEMYAEYKGGRSKTPGEFKEQMPYIRDLLTG
                     LGVQYYELPNYEADDIIGTLAEKVDKDQFDVVVLSGDRDLTQLASKEVKVDITVKGVS
                     DIESYTPEHVAEKYDGLTPKQIIDMKGLAGDASDNIPGVTKIGEKTAIKLLKQYGSVE
                     GIYEHIDEMKQSKMKENLINDKEQAFLSKKLATINTSAPVDVSIDSLKYEGKNLDKLV
                     PFYKEMDFNQFLSKLNIVEEEVKMDDILFEVVHEFKEEMFTTDMALYVEMMGDNYHTE
                     EIVGVAWGTEKKIYVTNDLSVFENRAFHSWITDPTRLKKVYDAKRTYVALNRYTGKTK
                     GIDFDVLLGAYLLDTNEKSTDIEGIAAHYGYNDIQSDEAVYGKGAKKGLPEEEELFFA
                     HLARKVAAINALTPKLSQELADKNQEDLFRKMELPLSIILAEMEISGIKVDATRLQEM
                     KGEFSARLREIEQKIYEEAGEEFNLNSPKQLGVILFEKMGLPVIKKTKTGYSTAVDVL
                     EQLREQAPIVEDILTYRQIAKIQSTYVEGLLKVIQSDGKVHTRYVQTLTQTGRLSSVD
                     PNLQNIPIRLDEGRKIRQAFVPREKDWLIYSSDYSQIELRVLAHISNDEHLKAAFLEG
                     QDIHASTAMRVFGIEKAEDVTPNMRRQAKAVNFGIVYGISDYGLSQNLGISRKAAQQY
                     IDTYFEKYPGVKEYMERIVREAKDQGYVETLYHRRRYLPDINSRNYNIRSFAERTAIN
                     TPIQGSAADILKIAMIELDKRLKETGLQATMLLQVHDELVFEVPEKELESLDKLVKEV
                     MEQAVSLHVPLITDSSWGKTWYEAK"
     gene            complement(65028..65711)
                     /locus_tag="LLC22_000736"
     CDS             complement(65028..65711)
                     /locus_tag="LLC22_000736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Bax inhibitor-1/YccA family protein"
                     /protein_id="HBK5434033.1"
                     /translation="MNNPSTSMSGINRFYAKVYGFLGMGLALSAVTSYLALWVFPLQL
                     ATFINNFPLGFVGLWIVELILVMVLGVKAQKNPSLAIGGFIAYSLLNGITLAVTLAYY
                     DIGTVTQAFLTATLMFMGMSVVGVTTKRDLSGVGRAGQAALIGVIIALVLNIFILRSS
                     VVELFISLLLVVIFAGITAYDNQSIRNIYVQTNGTAHSGIAVFMALKLYLDFINLFLA
                     FLRIFGRNN"
     gene            complement(65704..66189)
                     /locus_tag="LLC22_000737"
     CDS             complement(65704..66189)
                     /locus_tag="LLC22_000737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydratase"
                     /protein_id="HBK5434034.1"
                     /translation="MNIGKPRKLGKTINEIEEGDSLSLTESIEDNQLLLYLGLTNDAN
                     PLYIQHDFAQKTEYQQPIVPSVMLMGIITSAISKHLPGPGSHVVNFSVNFIEPVFHYE
                     TLTFQFEVIKVDKMKDVVTISVEAENTNEDRVLDAVVMVQPPQVPELEIAIESEGELN
                     E"
     gene            complement(66496..67830)
                     /locus_tag="LLC22_000738"
     CDS             complement(66496..67830)
                     /locus_tag="LLC22_000738"
                     /EC_number="6.3.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate--L-alanine ligase"
                     /protein_id="HBK5434035.1"
                     /translation="MENQNKLYHFVGIKGSGMSSLALVLHEQGLNVQGSDIEKYFFTQ
                     RDLEKANITILPFNADNVKPGMTIIAGNAFPDSHEEIQRAKELGLEVIRYHDFIGHFI
                     QNYTSIAVTGSHGKTSTTGLLSHVLSGVRPTSYLIGDGTGHGDPQAEFFSFEACEYRR
                     HFLAYSPDYAIMTNIDFDHPDYYTSIDDVFTAFQTMAGQVKKAIFAYGDDAYLRKLKA
                     NVPIYYYGVTENDDIQARNIERTTSGSAFDVYHGDEFVGHFTVPAFGKHNILNALGVI
                     AVAYFEKLDLKEVAEEMLTFPGVKRRFSEKIVADMTVVDDYAHHPAEIKATIDGARQK
                     YPDKEIIAVFQPHTFTRTIALMDEFAEALDLADKVYLCDIFGSAREEQGNVKIEDLGA
                     KIKKGGEVIKENNVSPLLDYHDAVVIFMGAGDVQKFEQAYEKLLSSTTKNVL"
     gene            complement(67961..68722)
                     /locus_tag="LLC22_000739"
     CDS             complement(67961..68722)
                     /locus_tag="LLC22_000739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBK5434036.1"
                     /translation="MEKSEQRNLKDWNQLLNFLAAPEEGNFEELTAPTLILAGNCLPI
                     LADKAAQMYLNGQVDQLFLVGGVGHATRILYENFEKQGFHFEDGMSESEICRQYLKEV
                     YDLPDKAFLIESKSTNSGENATFSLEILHSLGAVPEKILLMNDPTLQRRTRATFEKVW
                     QNEQTIFANAVPFVPEILHFSEEIIFTAKELNHQWPKEYFHALVLGEMERLHDDENGY
                     GPKGKDFIPHIDISEEVWSSYTRIKESIKTDFSRT"
     gene            complement(68738..69220)
                     /locus_tag="LLC22_000740"
     CDS             complement(68738..69220)
                     /locus_tag="LLC22_000740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SprT family protein"
                     /protein_id="HBK5434037.1"
                     /translation="MTQEELQQLVEEISLKSFQLPFKHQAMFNPRLRTTGGRYHLNDH
                     HLDFNAKLFEESDEETIAGIIKHELCHYHLHLAGRGYQHKDMDFKYLLKKTGGLRYAP
                     ALTKKQIKMEYYRCQDCSATICRKRRIDVRKYRCGRCHGEIKWIETKREDFNEAQKIR
                     "
     gene            complement(69240..71420)
                     /locus_tag="LLC22_000741"
     CDS             complement(69240..71420)
                     /locus_tag="LLC22_000741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding transcriptional accessory protein"
                     /protein_id="HBK5434038.1"
                     /translation="MTENLNQTIIQLVQKELSDYRPKQLTTVLNLLNEGNTVPFIARY
                     RKEMTGSLDEVQIREIEERYAYLENLEKRKTEVIRLIDEQGKLTPELEAEITQAVKMQ
                     QVEDLYRPYKQKRRTKATIAKEKGLEPLAKWLMQLTDGEVQSEAEKYIDKEKEVSSAE
                     EALHGAHEIIAEQVSDNAKFRTWIRSYTYNKGMYVSNVKDEQADEKGVYEMYYDFAEP
                     VHKMVSHRILATNRGEKEDILKVFFQVDEAAILAYLDRQIVKNPASPSSSFVREAYQD
                     SYKRFIQPAIERELRNELTEKADEQAIAIFGENLRNLLLQPPLKGKVVLGFDPAYRTG
                     CKLAVVDATGKVLAIEVIYPHKPAAQAKREAAGPAFIQLINKYQVDMVAIGNGTASRE
                     SELFVAEQLKSADHKTYYAIVNEAGASVYSASEIARKEFPHLQVEERSAVSIARRLQD
                     PLAELVKIDPKAVGVGQYQHDVSQKRLAEQLDFVVETAVNQVGVDVNTASPQLLQHIS
                     GLNKTTAQNIVIYREENGEFTARTQLKKVPRLGPKAYEQAIGFLRVPGGKNILDNTGI
                     HPESYSIAKEILTSVQLSEKELGTEEAVEKLTRLSVEKLAESLSVGEETLADILAGLT
                     QPGRDMRDEMPAPLLRTDVLSMEDLKPGMELTGTVRNVIDFGAFVDIGVKQDGLVHIS
                     KLSKKFVKHPTDVVSVGDIVTVWIEQVDTKKGRISLTMLSPYEE"
     gene            complement(71564..72295)
                     /locus_tag="LLC22_000742"
     CDS             complement(71564..72295)
                     /locus_tag="LLC22_000742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325746.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine protein phosphatase"
                     /protein_id="HBK5434039.1"
                     /translation="MKSLIYAIGDVHGKHELFEKLIHYYDPKIHQLVLLGDLNDRGPR
                     TKECFLLGKQLVEETGAIYLRGNHEEYFLQFLQSPEDWYAPYMRNGGKETFESLIHPG
                     ASEEYSPTEISMMIQSRYSELIKFLVQRPLYYEWENYLFVHAGVDLTKKDWRKTSLRD
                     FIWIREPFHEGKNNTGKTIVFGHTITPMLHGDMQTTDLWIQDHKIGMDGGAVFGGSLH
                     GVVFDKEGILQDIEYQNNEGPWHGI"
     gene            complement(72364..73305)
                     /locus_tag="LLC22_000743"
     CDS             complement(72364..73305)
                     /locus_tag="LLC22_000743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-related sulfurtransferase"
                     /protein_id="HBK5434040.1"
                     /translation="MDYQVLLYYNYTKIEEPEEFAKNHLAFCKSLDLKGRILVAEEGI
                     NGTVSGTVENTTAYMKAMKADPRFADTMFKIDPSEGHAFKKMFVRYRPELVSLKLEED
                     IDPNQVTGAYLSPQEFKEAILDEQTVVIDARNDYEYDLGHFRGAVRPDIRSFRELPDW
                     IREHKEEFMEKRVVTYCTGGIRCEKFSGWLVREGFKDVGQLHGGIATYGKDPEVQGEL
                     WDGKMYVFDERIAVDINQVDKQIVGRDWFDGTPCERYINCSNPECNRQILASIENEEK
                     HLGACSIECAKHPRNRYVQDHGISPEEAELRFTALIK"
BASE COUNT        21570 a        15400 c        11398 g        25099 t
ORIGIN      
        1 agatatcaat gatgatggct caagaaaaaa agtggagaaa gttggcggag acacccgacc
       61 agaggccgaa gctgctttac gaaaagtttt atcagatatt gacgaaacag gacaatactt
      121 tttaggtacg gatactcgag taaaacaata ccttgatttt tggatggagg aatacgttaa
      181 actaaatcta aaatacaata cctatgaaaa ctaccgattt accatcaaaa atcatataaa
      241 cggttattta ggaaagaaaa aacttacgga tctctcccct gctcttttac aaaatttcat
      301 caatgctgaa tttaaaaagg gttactcgaa gaaaacaatg actattactc actctgtcct
      361 taagaatgcg ctgaatatgg cggtttatcc ttggggatta atcaagcaaa atcctatgct
      421 gtatgtaaaa ataccaaaat atgaagcacg accaacgact aaaaaagatc taaaaatcat
      481 ttctcttgag gactttgatc atatgctaga aattactcct gaaggacatc ctttctatat
      541 tcctttgaat attggatttt atacgggaat gcgcgttggc gaagtttgtg gtctgacgtg
      601 ggatgatgtc gatttttcaa atggaacaat tactgtagag aaacaaatgg taaagaatga
      661 cggcgcatgg gtatatggta cgccaaagac aagcagttcc aatcgaacga tttttattgg
      721 acaaaccttg ctagcaattc tgaaaaaaca taagaaacaa caattagaaa atcgaatgaa
      781 gtatggaaag ctctacattg attcaaatgc agtatgtacg aaggaagacg gtgagctagt
      841 tacgccaagt gtagtgaaat ggaatactag gaggatatcg aatgcactct ccctctcttt
      901 taacttccat tctctcagac atactcatgc tacacttctt ctcgaaaatg gcgcaaaaat
      961 gaaagaaatc tctgaacgat tgggccacag cagaatttca attacgatgg atacttactc
     1021 gcatgtaaca gataagatga gaaatgaaac ggtcgatatc atggaaaatc ttagaaagaa
     1081 ttcttgattt ttgccaccga aaaaaaccac cggtggcaaa ccggtggcaa atccatgtaa
     1141 acatggttta ttttttacac tgttttcaaa caaacccttg ctatttcttc ggttcgtcct
     1201 cgtccatttt cgataccgac agctagctta taacccaagg tatatcaaca taaaaaaaaa
     1261 aaaaaatagg ctgtgacagc agcgtgacag caaaaaagat ggaaagttaa atatcaaacc
     1321 tcgtaatttc atttgcgagt gcttgatttg tttctggata taagtgtcca tatttgtcca
     1381 aagtagtttt aatagaggca tgacctagac gcttagatat tgcatagata tttttattat
     1441 gttcaattaa aaaggcaaca tgcgagtgtc ttaatccatg catatgaatt ggttttactc
     1501 ctgcaatttc agctaatttt tttattctgc ttaaaatagt tcttggagat ggcggtaatc
     1561 catcaaaaga aaaaaccaat tctatatttt tcccaattga ttgttgagtt tttttccatg
     1621 tttttaaatc ttcaacggtt tgtctgtcta acgaaattat ccgaatactt gatgtatttt
     1681 ttgtttcagc aaattcataa tcttgtcttg tacggatgta aattgactta tttacgctac
     1741 atctgccatt tattaagtca aagtctttcc attgtaacgc taagagctcc tcactcctta
     1801 cacctgtaac aaaaataaaa cgcatcaaac gtttataaaa ttcttcataa aaatccccgt
     1861 gataaacact attatatact ttcttaaatt catcaactgt ccaaaattct acttgaggac
     1921 gctgagtttt tattttacct atagtatcta caggattttc ttcaataatt tcaagtacaa
     1981 ttgccctttt aaaaactact ctcaacttat tgaatatctg tttaatataa tttggtgata
     2041 atggttgctc aatgcccttt tttacaacat ggattttcga taaaaactgt tgaaattcct
     2101 gtatatgaat tggtcgaatc tttacaacct gcatttctcc aaaaaaatcc aatgcacgtt
     2161 gtaaaatatg atctgttttc atatatgttt tttctacagt tcccaactta taccaaggaa
     2221 aaaaatactc tcgataaaaa tcatgaaacg ttattccttg cagacaaatt ccttgtgaat
     2281 cagaaaaact ttgttttaac tcttcgagtc cccttctagc ttctccttga gttttgaagc
     2341 ctcttctggt cacttgaatt ctttttccaa agcgatcttg tcctaaagtt gcagaaaaaa
     2401 accaagtgcc tctttttctg tctttataaa cattcgcaat tttcctcatt ttactattcc
     2461 tcccaagaaa tatggagaac ttcttctaaa attgaaatag gaattctttt tatttttgaa
     2521 ttacgataaa aaaagtatcc tttctcaact aaaagttctt tacattcctt gaagatttta
     2581 ttagcatagt actgagaaaa acctagatta atcaaatctt ttcgagtagc tgttttcatt
     2641 atagcacctt ccttactttt tttcatttat ttctatcagc tgcttttgtc aaaagcacat
     2701 aggaatttca cctctcccca agtttacggc gagccttacg gaagtatcat tatcccaact
     2761 ttaaatcatc gctttttatt gactataaaa attattttag aatatttatc gctccttctt
     2821 tacagcaaga aatcatggcg caactaaaat atgctcctta aagtgttaac gtactgatag
     2881 aatctattta attttcaatg aacaataggt tttctaccta aaagaatcta ctaattcctt
     2941 aactattaga agattctttt aaacagaaaa agtggaaagg agattttttt aattagttaa
     3001 ttttaaattt taagatcgct tctattaatt taatttctag ctgacttatc atatattcat
     3061 ctacataggt aacgaattga cctacctcgt taaatccatt tgtcaaacat aacttagcca
     3121 tataactatg ataatgtttg agtatcatct tgatcgaaat tggatctcct tctagagcag
     3181 ataagataat ggatagtgga actaataggt actgccgctt tttggattta tctaccatag
     3241 gtcatacccc attttcaatt gttcaactgc cttctttcgt tgataccaga taccacttgt
     3301 gctcatattg agaattttac cgatttcagc atcattaaaa cctgcaaaat aataaagtag
     3361 gataatcttt cttcttatct ccgataactg atcaattgct gctgataact tttgatctga
     3421 aattaatatt tccattccaa ataagaaata gacatcttgt tcatcaaaat gagtttggga
     3481 atacctgcct tcatttgaat ctgccaatgg ttcctcatta tcctttatgt tagcatttcg
     3541 ttttcgaata gacttagctt cgtttcgtaa tactttttta cagtaggcat caaattggtg
     3601 ttgtatagat atgtcattgt aatgttgttg catgataata tgctcctttt tccccctttc
     3661 cactaataca acaatcagag agcccctttt tttcgaaaaa actagaaaaa aacataaaaa
     3721 tatttatcat tctttaaaca gaaaatcttt ctataaaaaa caaaaaaacg attaggctag
     3781 gctaatcgtt ttttgaacat tcttaaaaaa atccaaatta ttttttataa ctgaaattgg
     3841 gtattgatga ccatcgtttc tgtagatagt gagcaatcat tttaggtttt ctatctctag
     3901 taaagattcc tttcttattt ccttgcactc ttaaaatccc ttgactcgtt gcaaaatctg
     3961 caaaattcca cacttgttca ccaacaaaat tttcacatgt atctattact tcgtgatttg
     4021 cttcgtaata agccacttga tactcttctg taaacattgt tggtactgta tcatgaaatc
     4081 cagctactgt atctgctcca tattctgtaa acattattgg cgtatcagga catctttctt
     4141 tccatccatc tagctctttt ttcaacagat attttgcatg tgccagatcc cctcccgaaa
     4201 cataccaacc ataataacga tttaaacata aaacatcgac aatatctcct accttacaaa
     4261 tatctggcgt tgattttaga taagtaacta ttgttacagg tcttttctgc ggatcaagtt
     4321 ctttagttaa ttcaactaaa ggttcaaaat attctttagc accttcggaa tccgaatctg
     4381 gttcatttgc aatagaccac attacaacac ttgggtggtt cttgtcgcgt tctatcaatt
     4441 ccttgatcac cgttttatga gaattttctg ttcgtatctc tttccacgta ttatgttttt
     4501 ccacattatc atctaataaa gtggccatga aatttaaatg taaccctact gcaggtactt
     4561 catcaataac tacaatacct tctcgatctg ctaatcgcat aatttcttct gagtaaggat
     4621 aatgtgatgt tctaaaagaa ttagcaccta tccatttcat taaattaaaa tctttaatat
     4681 ttacagcctc attcaaacca cgtccattaa catacgaatc ctcatgctta ccaaatcctt
     4741 taaaataaaa aggtttatta ttaatcaaaa atttgccatt ggtaacctga acactgcgaa
     4801 taccaaattc ttctgtatag gtatcgatca ctttattatc atcaattaaa ctaattttca
     4861 tactatataa ataagcatct agaggttccc aaaaaattgg attcttaagc tgaatcattc
     4921 ctttctttcc ttcagcttca gctacaagtt gagcctcttc gtcatatatc gctattaaga
     4981 tttttccggt ccattctgta tcgatattga attctacact tgcatccaaa tcagttattc
     5041 ttgtattaat agtaatatca cttatatagt ctttcggagt tgtatataac ttaacaggtc
     5101 tatgaatacc tgcataattg aagaaatcaa aattaactaa gttttccttt tttatatccc
     5161 cattttcctg tactgtttcc ttcataatcc ccacaggtaa agtactatcg tcaataatat
     5221 tgtttacagc aactgtaatt cgattattcc cgtcttttac aaaccgatta atttcagact
     5281 caaatggtgt aaacccacct ttgtgttgag taatcaactt tccattcaaa aaaacttttg
     5341 cttcatgtgt tgcagatcca aaacgaagaa ctaatctttc ttctaataat cttttaggaa
     5401 gagtcacttc tttttcatac cacacccatc caacatgatt tctaatgttc tctgtttcaa
     5461 ataaatcatt ataagaagag ggaactgaaa tcggataact ctctttttca tttattggtt
     5521 ctaaagcaag ttcttcctgt aagtcatcat ttgtatctaa tttaaatctc cagagaccgc
     5581 ttaagtcaat tacttgcctc gtctctgtca taatgggata caacatataa accactccta
     5641 tctaaatatt aaataaatgt atcctttaaa ccacaataag catctattgg acttactccc
     5701 ttaaattcag aaagacccat tagtttgtcc accaatattt ctaaagtttc ttgttttcca
     5761 tcataagtat taatataagt ctttacttga ggtacatcag ccaaatgaaa cggacactgt
     5821 acagatacaa aaattgttgg aatttcatga atgtaaaacg gtatatccgg agttccttta
     5881 cttgctggcc agacaattcg ttgaactgtg cctggattaa cattagctat attaatgatc
     5941 aagtcatatt ttttagttaa atttttaatt ggtctcttag cagcatatat tccagctata
     6001 tttttaattt tttcttcttg cgataatcct ttcaactctt cttcaggtga aatgtatttt
     6061 tcaacttcaa atccttttgc tgacaaaatc tgtttcaata aatcaatggc ttgaggtcta
     6121 tttccagcaa ctacttcacc aaacccacct tttaccccat gtacatctac tagtaaaatc
     6181 cttttatatt tttctggttc aataggccaa atatcttgtt tatctttaac taatgtaatt
     6241 gcttggtcag ccacctcttt aaaaattgat ttattttcaa ttaaaccaat tttttccaga
     6301 gcttcttgct taggtaataa aatttgttct tttgcttttt tgtgtaatcc caatttagct
     6361 tttaacccta aaattctttt taaggcatct aataaccgat catcagagat aattccttta
     6421 cgataacctt ccatcatata attaaagtct tcatctggat cattaaaaaa tagaaataga
     6481 tcacatccag ctgcaataga agtgggcaat aattctgatc gtttcattgc cccagtcatt
     6541 cctaacatat gactagcatc agtaactact aatccattaa atccgagttt tcctctaagt
     6601 aagtcagtga ttaattcttt tgataaagtt gcaggaagta aatcttcatc tttcagatca
     6661 ggattaaaat gttttgaata agctggcata tggatatgac ctgccataat cgaaggtaat
     6721 ccagcttcta ttaaacctga gtatactttt ccaaaagaat tatcccattc ttccgtacct
     6781 aaactattaa tactaaaaga tagatgctga tctcgttcgt caataccgtc accagggaaa
     6841 tgtttagctg caggcaaaat tccactctcc tgaatacctt tcatataagc taaactaagt
     6901 tctaaaactt tatcagggtt ttgtccaaaa gatcgactag aaatgatagg atttctccaa
     6961 tttctattaa tatctacaat aggagcaaaa ctccagttac atccaatagc cgatgcttca
     7021 atcccagaaa ctctccctaa ttcataagca tatttcgcat catttgttgc accaattttt
     7081 acttctacac caacttcagt accatctgta caagctccgt taccacctgc ttccgtatta
     7141 gcagcaatta ataaaggaat tttgctttct gtttgtagga tatagttttg atcatatacc
     7201 tcatcagcag ttcctgggtt atatcgtaca gctccaatat ggtactgatt gaccatatta
     7261 ctcaagtaat ttttatcacg actagatccc atattaacaa acaattgacc tattttttct
     7321 tccaaagtca tagaatcaat cgtctcttca atccaagaaa tagcatcttc atctaaatta
     7381 tatggttttt ttcgtaagtc tacttttata gtcattttct ttctcctcta cttattagta
     7441 agatttttcc aaaaagtatc tataaatttt tgttcaatat ctacatactc tcccgataaa
     7501 catttaaata aaacatcagt tcttaagttt tcccatgatt ctttttcttt attaaccaaa
     7561 ataggataaa agaaaacttt atttttattt gcagcttcta gatcaccagg agaatcacca
     7621 atcattaata tcttatccaa atcacaacca ttttcaatta cacttcgaat aatgtcttct
     7681 ttttttcctt tatcttgaca acacagttca tcaactaatg ataataattc atgtctttcc
     7741 cattcttctt gaacagcttc cttattagct gagcttacaa taattatctt cccatatttt
     7801 ttcagagctt ttatagtatc tctagcactt aaaaagggtt tatctaatcc tttagcttga
     7861 ctaatctgtt gattgacttc ttccgaccat tttaaagctt ttaataaatc ctctgactga
     7921 taatattcta tttccctctt caaagatgga ttagacaatt cttttgttag agatacccag
     7981 tgctttaatc gattaatgga tgttacatca tttttttcta atgttttaac taaacctaaa
     8041 aatctgttta ttccacgagt ctctgaatat aaattaatat tattccaatc ctgtaggaat
     8101 ttttctctat gatgaacatc aaaaatctct gcagcaattg gtccgaaaaa gagattgtgt
     8161 ttataagtca tcgtatccat aacacagcca tctgaatcaa tacaaaatat ccaattattc
     8221 atatttctct cctatttata tttttgtttt aaaagctcgc aattttctaa gactttatct
     8281 ttagataatg gataaaggaa aaataaaatt aatcctacaa taaaaaaaca aattgatgga
     8341 attaatgttg aagcgttata taacttttct aaaacatctc ccgtttgtat atttgctaaa
     8401 gagtcatagc ctataataga aagagtccaa cctccgacgc ctccagctag agcttgacct
     8461 atttttctag caaaagaata taccgcatat acggtcccat cttctctttg atcagacttt
     8521 acttcttgat catcaataac atcagtaata tttgcccaaa taacagtatt aaacacaccc
     8581 aaacccatat agccaaccga actaagaatt aagaatacat acatattact agtttttatc
     8641 aaaaataaga tcaaatatac tattgctgaa aagaacattc ctactgatgc cagttctttt
     8701 tttccatatt ttttacttaa aaacaaagtt aaaggtgaaa caactattaa aaccaaaata
     8761 ggattgataa aattcattaa aactattccc tgtgcatcat tatagtaatc aggaaataca
     8821 taattattca tactcataat taataattga gcaaggagta agaaaatagc cgcaccaatt
     8881 atagaaagta atgccctatt tttaactaac ccttttaaag attttaacaa tgaaactttg
     8941 aattgagatt ggtcaattct tactcgttca gtagttagtt tataacatat taaataacaa
     9001 ataagtgcac atatcgaaaa tattcccgca acaattgtaa aagttgatcc accacgaact
     9061 atttgagcgc ctgaatcatc tcttgtataa ataaataatg gtgttaatac accaatgatc
     9121 aaacttgcta aagtagctcc aacatttcgg aatgtcgata gcattgttct ttcttctgta
     9181 atagaagtaa tagctgatgc cattgatcca taaggaatat ttatagatgt gtaaaaaata
     9241 ctcccccata atatatacgt aacatacatg tatactacct taacgctcat agaagctgaa
     9301 atcatagaag tttgatacat taaaaaactt gctaaagcga ctggaccact cattcttaaa
     9361 atccacggtt taaacttacc ctgcttagtt gctttcgatc tatcaacaat acgccccata
     9421 gttacatcag taactgcatc gataaatctt gctactaaaa ataatgttcc aacggcagct
     9481 ccgcttatcc ccaatacttt tgtataaaag atcattaaaa aagaactagc aaaaatgaaa
     9541 gtaaaatcgt ttccaaaatc tccaaacata tatcctattt tgtctcttat accaaatttt
     9601 ctttccatac aattctctcc cttcttttgt taagcgtttt cattcttatg aaagtacgta
     9661 ctatactctg aagcgtaaag agtcagtatt tattttttac atttcagagt attatttgtt
     9721 ttttctccta ataattcttt atctcataaa acttatctat atatttacta gctactcgac
     9781 ttacttcttc aaaatcacct ttttcaacag aagccaataa attcccacct acaccaactg
     9841 caacaactcc tacttcaaac caatcttcta agttctctag acttactccg ccagtaggca
     9901 ttatatttac gtgtggtaat ggagcttgat aggcttttac aatggatgga ccaaaagcag
     9961 aacctgggaa tagtttaatg atatctacgc cagcagtaag tgcctccttt atctcagtaa
    10021 ttgtcataca acctggtaaa taaggaattt gatataaatt acaaatctca gctgtttgtc
    10081 gatcaaaaga tggactaacg atatattctg ccccagccat aattgcgata cgagcagtaa
    10141 acgcatctaa aaccgtaccg gctccgatta ttacatcttt ttgatcagca tattttttag
    10201 caatttcttt gattatttct tcagcattag gaactgtaaa agttagttca atccctttaa
    10261 ttccacccgc aataattgaa tttattgctt taatggcctc atccttattt ttcccacgta
    10321 caaccgcaat cactccagcc gcttctaact tacttaaaat ttctactttt ttcatatcta
    10381 tctcctctat ctccttcttt tatggataca tactttgtct agctgtacta acttaaaaag
    10441 aataaattta agcttttatt tcaagtatta ttttctactt ccgatttcaa aaaaattaaa
    10501 ataattatac gcattacgat aacaaatatt ctccactatc tgactaagat acatttcatc
    10561 atctggaatt cggcctgctt taacccactc gcttagtaat tgacataata ctcgacgaaa
    10621 atactcatgg cgaggatagc ttagaaaact tcgagaatca gtcaacatac ctgtaaaatt
    10681 cgacaacaaa ctttgttgcg ccatcgtagt caactgttga cgcattcctt cagctgtatc
    10741 attgaaccac caagcacatc ccaattggat tttttgaatc ataccccctt ggaagctttg
    10801 cattgctgtt gctagtggaa gccaatcagt tggatttaat gaatataaaa ttgtttttgg
    10861 taagcaccca ctcttttcag cggtatcgaa caatgctaca acattttgtg tcaaactagc
    10921 ttgatccccc atcgaatcac caccgacatc tactccaatt tgttccttta atatacttga
    10981 attatttctt aaagcattta aatgcatttg catcgtccaa ccatatcttg tatactcaga
    11041 catcaaatgt aattgaatac ctgtaacaaa ttgtgcaatt tctgataaat ggaaatccgt
    11101 ttttcctgct aaagctttta ttaacagatt gtcgagtatt ttttcatctg ctatttcata
    11161 aaaataagta ttcaaaccgt gatctgctaa tcgacagcca atttgatgaa aatgatccac
    11221 tcgttggctc aatgcttgct tcaacccatt aaagtctttg attggtatag ccgctgcttg
    11281 actaagtttt aaaatatagt tcgaaaagcc tgatgatttg atactccaga ccttatctgg
    11341 acggaaagta ggtaatacct tgaaagaatt atcctgttta gaaagctcag tatgataccc
    11401 caagtcatct gtaggatcat ccgttgtaca gatggctttc acatccatca tctccaacaa
    11461 ttctttcggg cgataggaat ccgtttggat tttttcgtta gcacgtcgcc aaatttctgg
    11521 tgcattcttc tcagaaattg tcaaatcaat atcaaagtaa cgttgtaatt ccaaatgaga
    11581 ccattcaaaa ataggattac ctggcgcctt ctccactgtt tttacaaaag ctaaaaattt
    11641 ttcataatca tcacctggac cactgatcaa ctcttcttct ataccattag ctcgcatcaa
    11701 tcgccattta taatgatctc cagctccttt atcatttaac catacctgag tcaaattctt
    11761 gtattgctta ttttctagca aatatgctgg gtctaaatga caatgatagt cgataattgg
    11821 ttggtgtttt gcaaatttat gaaaaagtct tttagctatt tcattctcta ataaaaagtt
    11881 cttatctaaa aacatattta aacactcctt tccttccgtt agtttttaga agagaaaatt
    11941 tttcctctaa ataaactcca ttatataatt atttactcgc ccccttttca agcgcttccc
    12001 aaataccatt taaataaact gcacctagag ctcggtcata taatccataa ccaggtctac
    12061 cggtttctcc ccaaatcatc cgaccatgat ctggacgaat atagccatta aatccattat
    12121 cgtacattgt ttttaatatc ttatacatat ctagagaacc atattctgat ttatgcggcg
    12181 cttcgtaaaa atcgagtcca ttgtcactta aatatttgat attacgaaca tgtgcaaaag
    12241 gaatccgatc ccgttgacaa aattcagata gaatttcata gacatcatta tctggtcgtt
    12301 ctgcaatact tccagtacat aatgtaatac cattagaagg agaatccact acattacaca
    12361 accaatctaa atcgtcacga tttttaacaa tacgaggtaa tccgaaaatg gaatatggtg
    12421 gatcatctgg gtgaactgcc attttaatcc caacttcttc acatgtcggg ataattgctt
    12481 tgagaaaata tgcaaagttc tctcgtaatt tctcttcatc aacttcttta taggcttcta
    12541 ataattgctt aatttgtgat aaccgatgag gttcccaacc cggcaattca aaattattag
    12601 tagaattttc tacttttcta ataatttcct ccggatcagt agggatattt tttgaaatat
    12661 aggctaacgt agaagaccca tcatctaaac gataatccaa atccgatttt acccaatcaa
    12721 atactggcat aaaattataa cagataacct caatcccaaa ttctgccaaa ttgcgaatcg
    12781 tctgtttata attctcaatg tattgatctc gtgtttgtaa accaattttg atatcatcat
    12841 gaacattaac actctcaata actttcaagg taagtccatt ggcttcgact tcatctttta
    12901 aagatttaat tcgttctctc ggccaaacct ctccggctgg tatatccatt aatgttccaa
    12961 caattccttt cattgctggg atctgacgaa tttcttgtag tgagattttt tcttcatttg
    13021 ccccatacca tctaaaagtc atttccatag ttactttcct ccaacttctg ttatatattt
    13081 attgattgtt ttacgaactg cttgaggacc tactagcatt tcgcaaaaga ttttttcagt
    13141 tttctttcct accccaactt gatataaatc taaaccaaaa atttctttat tttctaaaat
    13201 ttcctgtacc gcacaatgaa tatttgaagg atcttgttca cctaatttca atactgataa
    13261 tttatcctgc aactctacca ataacggatc aggacttggc acaaaatttt ccccttgatc
    13321 atcgactgcc agtaaataac gtaaccaagc agcaatagcg ataggaataa atgttagatt
    13381 ttctgcattt ccgtcttttt cgacatactt tttaattgtt tcaccatagc gaatcgctac
    13441 tttttgagaa gtatctgttg caattcgttg tggtgtatct ggaatatagg gattaggcaa
    13501 acgtttatta attacttcat caataaattg ttttggatca ataatgcctg gattttcaac
    13561 tactggtaaa ccttctaaat aacctattcc tttgattaaa ccaaccaaat catcatcctg
    13621 catctctgct gaaattgatt gatatcctag cagacaacct gttactgcca aagcagtatg
    13681 aagtggattc aagcttgtcg taaccttcat gatgtctgct ttatcaaccg tctctctatc
    13741 tgtcataatc acaccagcct tttccaattt aggccggcca tttggaaaac tatcttcaat
    13801 aactaaataa tgaactacct cagtattagt gaaagcagca atattggtat gtttttttgt
    13861 gtgaatgata tctaaatcct cgagccccat catcaataga tcttccttta cattctctga
    13921 aggatttggc gtaattcgat caatcatact ccaaggaaaa gtcacttttt ctttatcctt
    13981 taaataagca ataaattttt cagaaacata tccttctttt tgccaagctt ctgcaatcgt
    14041 aaaaatacta tcttgaaaac gttgaccatt ctgtgagaaa ttatcagtag aaaccatcgc
    14101 aatcggcaac tctccagcat taaatctgct atataacaag gatgttacaa tactcatcgt
    14161 atgttgagga ttgctaggtc cagatttgat atcagctttg actaccgaaa agaattgccc
    14221 tttagaatct tttaaactgt aacctttttc agtaatagta aacgttgtaa actgtaattt
    14281 aggatcttca aaatatttaa ccactctttg atagtccgct atattcttcg gattgcaata
    14341 taaactatca gccgttactg ccaaaagcct ttttttgagt tcaccatctc cactcataac
    14401 aatttccaaa atgtcattgt tgtagtcatg ataagctttt tccactactt cttcatcaaa
    14461 tgtttcacac acaactactc ctgtttctaa ttcattttga tctgctaagc attgagcaat
    14521 ttctgcatga aatcctcgat aaagatttcc tccaccaaaa tgaagccata ctggatgttg
    14581 ctggccttct tgcttaactt ctttgacatc aaaacacggc agtagaatct gcatttcatt
    14641 gaattcttcg atagaatttt gccaattttt aatcgaaacc ataattaacc tccttaaact
    14701 aatatgttag ttttgataca ttttatattt taaaacccgt tgtaaccgtt gtcaatataa
    14761 aaatggaata aacttgcttt ttttctacca tatcagaatt attgtatttt ttattcagaa
    14821 aaataaaata ctccttcttt ttggactgat tttatcgaaa cttatttttt tctttttttc
    14881 atgtattctt ttatttttat aactagtgta ttacttcaaa atttgatatt atatggcatg
    14941 aacagaatta aaatatcagc taaaataaaa gttaaggagc attgagtatg acaattaaaa
    15001 ctagtctcca aaatcaagct taccaatcta ttcgccgaca aattatctat gctgacttag
    15061 aacctggaaa aaaagtatca gaaaaaaaat tagaagaaac actttctatt ggtcgtacac
    15121 caatacgtga agcactgatt caactccgac aacatggtct tgttgataca attcctcaaa
    15181 gcggaaatta tatctcatta attgatttag attcggccaa aaatgctcga tttgtcagag
    15241 aacatttgga acgacaaatt atgttagagt gttgtgccaa aattaataac caaaaaaaac
    15301 ggattttaga aactataatt tcagaacaag aaaaagctgt tagtcaaaaa aatgctcgta
    15361 gtttttttca taatgataat ttattccata aagcttgttt tgaaattgca gagcgagaag
    15421 aagtatggca atggttagaa aataacaata cacacttaga acgatttcgt tggctacgag
    15481 taaaaacgga aggattaaag tgggaaaaaa ttatggaaca acattatcaa ctatttgagg
    15541 cattaacaaa acaagatcca gaagaagcta actttctaac atcgttgcat cttcatttaa
    15601 tgcttaatga gcaaaatatt gttttagcta ctcatccaaa atatttcaaa agtatataac
    15661 ttttaactct ttttaaatta aatgattgtt ctgatcagaa aaatatcgct tgttttctta
    15721 ttatgtaata tatttcataa actattctgc ataacaacta ttgtttgtac tttttacatt
    15781 ggataactaa ttatgactgc tgataacttt tgatattaaa ctagtatctc caatccaaat
    15841 aaaaaataga tatcttgttc atcaaaatta gttcatggat acttaccttc atttacatca
    15901 ttcagcggtt tctcattttc ttttattcta ttatttcatt ttctaataga cttggcttca
    15961 tttcgcaata cttttttaca ataggcatca aattggtgtt gtttagatat ttagttgtag
    16021 ttttgtgaca tgataagtat gctccttttt gtcttttcca ctaatacaac gatcaaaggg
    16081 tgcttttttc aaaaaactag aaaaatcaaa ataagattcg tattttgatt ctatatatcc
    16141 tgtttcaact acatcttata tttcataata gaataaatag ccttttgcat agctgcttaa
    16201 cttataagaa attgcaattt acttcttcaa agtgaaaacg aatatgagta aaataaaatt
    16261 attcttctta cagataatta aaaatagcgc gtaacaaaaa tcggcattca atcacataat
    16321 taggattgat gccgattact tatattctac gtatagtttt agtattcttt ttttatcacc
    16381 agtaaccaat tgagaacagt cctaaagcag aatagtcttt tatctcaaaa cgcttaattt
    16441 caggcttagg aatatgaata atcttttgag tatattcttt ctcttttaat cttactgaag
    16501 aaataccact gcctatcttt tttacaaata tttcatttgg tgtacagact aataaaacaa
    16561 tatttgtaat caatccttgc actaaagaat taaaaggaag actatttaaa acagggtgtg
    16621 cataactata acatgtgaag tagttatttt gaactttaac ttttaaaaac tttaaaaata
    16681 atcttatttg ttcttctaaa caatcatcta tactcatata atcactccac taattacttc
    16741 ccccaacaag aaatagcatt aatagctata ccagctgcaa tagttgcagc attgaatttt
    16801 gcaaattgtg caggagttaa acttcttttt gctacatcta aaagtatttt aacagcataa
    16861 tcataatttt tcccttgcaa cgcattaatt aaagtttgca ttagattttc acgattaagt
    16921 atatcccaaa caacacacca aatggtaatg agttcataac aacacatgca gcatactttt
    16981 gaagatcacg tttttgacgc tttcctgttg gctgcacaaa attttctaaa ataaatttcc
    17041 ctgctatacc ttcagagcca tctaattcag cttttttctg tatagcttct aaatcagtaa
    17101 ctatatattg atgtgtttct gtatcaacat aaccagcttc ttctaaatag aatttcaaac
    17161 tctctactgc ctgttgtctt tgtgtttcta tatcaggaac ttcattcact ttttcagcag
    17221 cataaacact ggttccggca ccgactaacg tacttaatcc aattaacatt acacctaata
    17281 atgaaaaaaa cttaaaaaaa cgactcattt ttatccctcc tgaaaagtat tgttgattat
    17341 caatttttat ccttttaagc tgttcaataa gacgttttta cgttccttcc gtttctattt
    17401 tattctttct gtcttataac agcttttttc aagtaaagaa cgatataatt cttcttaaaa
    17461 aacagtctat tttttcggta tataataaaa ttgtattgtt acctacatag cgaaacagta
    17521 ccaacatcat tcaaatgaag atagcaaatt tgcttcttcc tttttcttaa gtgactattt
    17581 aaataaccag aaaaaaacta aaatcacact gatatcccaa ataaattgaa ataaaggaaa
    17641 aagttttttt ctaccatgat agtttttcaa aaaatagaaa ctcgtactat ttaaaagtaa
    17701 aataactagc atcgtaaaga ctactgattt atctaaactt ctataaaaaa gtgggctaaa
    17761 taataaagta attaaaaaat gaactatttg atattgtttt ttttcatatt aacagatcgc
    17821 agctcctgcg attccatagg ctgttcctac agcaaatgga ataacggctg cacctactcc
    17881 cgtaaggctt aaacctagag cagcagctgt ataaatccca gaatgtagaa gtccagcccc
    17941 agtgaaagcc caactgcagg cacttcgttc accagtttta ttatttgttt tttgatcttt
    18001 catataattc tcaacttcat gaagctgatc ggttagccat ccatggccat tttttttgaa
    18061 tagaacgatt aaattcattt agatactgtt ggatttcaga aactgtaatt tcagaattaa
    18121 ttctatctaa acttgatttt aaatcactct catcaataat atatactaat cgatttcctt
    18181 tagaatcttt atgtgtggct aaattatttt gaatgatatt tatttcagtt tcttgttgtt
    18241 ttactaaaaa attatttgtt tcagaagcat cgacacttat tccagcgcta acaaaagtac
    18301 ttaaacctat taagaaaaca cctaaaatac caaatatttt aactattctt ttcataattt
    18361 ttcctactta aaaataagtt atttttaaaa tatcttgatt atgaattcat cccccaaagg
    18421 ccttttaaga ttgatacagc agtccgttca cttcttttag acttgtcata taagtctttt
    18481 aaatgatccc ataccagact agtttgtcta tctagcttca atccattaaa cgctaatgaa
    18541 cggttcattt tttctattac tttagataaa gctacagaaa tttttatacc ttcacaacgc
    18601 gcatcttgga tttcaataat agtatcatca attagttttt gaatttcttt cctatcaaca
    18661 tattcaatct tagaaagaga atcttttaaa gctactaatg attcaacgat ttcttttttc
    18721 tcttcagaca ttctcttcct ccttctagtg acccgtaaag ccatgtagag cagagtccat
    18781 tgaaccagta attacactat ctacaacgcc attccaattt actctacatt ttccattttt
    18841 cagatttgtc ggtccatacg gatagacttt ttgacattca atgttcggat tataccagat
    18901 aggattatac cattcagccg cagaagcaga ttcagtcgat acaaacaatc ccacaccaac
    18961 aaaaccaata cacatcacac tatagccaat taattttttc atctcgtatc catctcctaa
    19021 aaaatagaat agttcttgta gttattcata agacatattt tttccgtttt tgttttatcc
    19081 tttctgtcct ataacaactt ttttcaagta aagaatgaca tacttcttct taaaaaaaca
    19141 gtctgttttt ttctattttt tcggtgcata ataaatatga gtgttcattt tttattttaa
    19201 tacacacttc gtacataata aatcttgatc gcatcaatct tttgagcttc ttgatctact
    19261 ttcaattgaa gtaatacaaa ttgagtgacc tcattcgttg tttcttctcc aaataacaaa
    19321 tattgatccg gattctctat atcttgtgtc acctggtgaa gtttcccagt tgttttcatt
    19381 tgtacatgcg ggtctacatc aatactattg tctttaatac aacgatccgt catatagtcc
    19441 ctcacagctt gattgcgttt ataaacatct gtgaaattac tccattttct agcaaaatct
    19501 tttaagaaat tttttgtcat ttcatctatt tgttgcgctg tctcgtcttc taatgaacca
    19561 atttgactgt tactttcagt actttgaaga gttccacttg tttcttttac tgcttcgatt
    19621 gtttcttctg tcgttgtcaa ttgtgttttt tgtttttcag aagaaaacca atgacaacca
    19681 gtaagaccta tcaaacataa ccaactaaat actaaaatta ttcctttttt cacgcttcta
    19741 gacactgcct ttcttatttc accttacgaa ccagactacg aatttttgtt tgattgtacg
    19801 tgcgttgata ccgagccata atccgtcctt gctcggcatt ctgttccaca ctagagaaat
    19861 gttgtccgcc atctgaaaca tctgttataa ttccggtgtg accatagatt ccaggagaca
    19921 atgcaccacc tgcttgccaa ttcaccacat ctcctgcttg taaatcactt ggttttgggt
    19981 tcatgatcac ttgccaacca taggctgtcc aatcataatc ttcccctatt aacatcgcaa
    20041 acatgtgtcc agaacccatt aactgtgggc cacctagttg ggatacatac cacgccgtgc
    20101 caccataaca ctctccatta tttaccgatc gtccaatgat ccgatctaaa actttcgcat
    20161 tacctttact tttccctgca acaagtgacg atttttttgt tggtaggcta ttccaatgtt
    20221 tgatcgcaaa agtatcatat tctgttaagt tataagactt tatgatactc atcgctcctt
    20281 ggtaatacgg actgccttcg gtaatacctg ccgccgcata gcctccacga cctagaatca
    20341 ataaacaact cccaggatct ttattgccca cacattgatt aaagttgctt tgactcgcca
    20401 ccaaaaagcc gtaatagtca taacaatctt tcaggttcgg aaacttcata tagaagccac
    20461 cttcagaacc accaatcccc cgtgcagaac cttgtggata gggacaacca ggaaaccagg
    20521 taatcccaaa gaagtttgta tcgtttcttc cagattgtga ttgtccataa gtcgattcat
    20581 aacctaattg agaaagaatc acacttggta ataactgata ctttaccgct gcaccgactg
    20641 ctgcttgcgc atgttcatct gtgatcggac cacgtccttt aatctctgaa aaaatcggta
    20701 atccttcggt atattcccaa ttaaaagcga cagctagacc tgtagcctct cctccatcct
    20761 cggaaagttc tcctgaaaaa aagaatggca atagaaaaaa gggaagaata aagaaaagca
    20821 gacaacctag acaccctttc ttcatttctt cctcatcctt tcttcgataa tggtttttga
    20881 actgttcgtc cttttggtaa agtaaaatcg gttcctggtt ttgcgtccaa aatcggcaat
    20941 gtttcatttt tcttttctat ttttttcgat tgctctactg gattattaaa agaagaaaat
    21001 gcaggttgta aggattttgg tacggaaatc gacggtttac tttcagacga acgttgtatc
    21061 tgtcgttgca cagaacgatt tcctgataga gtggctaccg acgacttagg aacagagtat
    21121 tgattcaata actgctgcat tgctggataa ctcccatttt tcgcctgatt tttcacttgg
    21181 tgaatctgtt gtgaaagaga accagcagct gttaattgtg gcacgggtac ttttccagca
    21241 ggcaacggaa tcgattgacc aacaaaagcg atacctttat ttaacaatgg ttttctttga
    21301 ttattccctt gttgcttact cgattgtgcc aacgattgta cctgttgttt cggtcttact
    21361 gaattcatgg acgaatttgg aatcaaacca tttgaaagac cagaattcca ctctgttttt
    21421 gatttggtag aagacatttc aggctctacc ccatgataac gaacatgacg accactataa
    21481 ggcaagtctt gatttgaacg cccacctagt tcaaagggat taatcacttg cccccctttt
    21541 accgattctt gtggtgtacg tttttgttga aacttttgaa atccatgtat cgctgcagaa
    21601 gcgagtggat tcgttgctcg gtacacattc cctgctaatc ctgcaccttt gattgccaaa
    21661 ttttgcccag cagttgatag ttgaccaggc agttgtttca tttgagacaa agaatgactt
    21721 gctatgtttt tcgtgttatt tatggtttga tctgcagctc ctaaccctag tttctttaat
    21781 aaatctttcc gttttacaat gagtaaaatt gataggagtg ctttgacaaa catatttcct
    21841 aaaaaaccaa aaacagtatt cattagaatt aaatcgtcta ctatgttata gatcaaaaat
    21901 gccaccaaaa taatcacact gtaaaaagat ttttgaaaca tcaagctcaa aaaggacttt
    21961 aaggtattca tgatcatata atcaaatgct ggaacaaaag aagcgagtaa tgaaaaagga
    22021 atcacaagta ataaacacaa caccaacatt tgaaagataa aacgaatcat gccaatcact
    22081 acaagtggta atccaatact tagattaagc aatggcacca tagaaccaac gactgcttta
    22141 taaacagctt tagttggttg aatatagaca cgataagcct tctttttccc tctatcttct
    22201 cctgcagcag tggtcacttt tgtctcaata tcagataatt cttcacttga cgcttccttg
    22261 gctagaaatt cttgtggttc aatctctgct tgatacaatt cttctaaatt tgttgtccca
    22321 taatttaaca atagatacgg atcaacaaca gccgctttat aataaagttg gcgcactttt
    22381 tgaatggctt ccttttgtgt cgttggcact aaaacaccat tgacatcttt tgtcgccaat
    22441 tcatctagac tatttgtagc agaaaaaata aagccttcta cctccacgga caaatcattt
    22501 aaccctttag taaaagcttc tcctttacta ggtacgttac taccatagcc aaaccaaacc
    22561 attgaaaaaa tgacaacaaa gagaaatcga ataaacacca tttttgcgta atgtttccct
    22621 ctaaatatac gaagagtaaa tagatataac acatacaaga cgacaatccc cgcaccaata
    22681 ggatcgtata ttttcgaata aatagtatcc gaaaaagtga aaaactggtg aattaactcg
    22741 ttcattgcag ctccttcata gagcttctca atgacaaaat caaggccttg ccaaatcaat
    22801 ttacttaaac taaagaacat attcgtcatc atttttagaa aatctgtgcc atttgctcca
    22861 aataacattt tgcctaatga aaattcacta tcagataaat aagaagaaaa ggtatcaata
    22921 tgaaatttcc cgatctcata gatcgattga tccacctgtt tttctaccgc atataccaat
    22981 ccaccaacaa aaaacagtcc gaatccaacc gttaaaaaaa gccaaacgca ccatttcttt
    23041 tccttacgct ttatataagc cattgtttca cctcgtttct attgcatgat taacgtatcc
    23101 tgttcttcta tttgagagtg acttgttttt tccgttgttt gtaatgcagc ggtcatttct
    23161 tcaaacaaac tgtgtacatt gagttttcct acacgtccat agggatctaa catccaacac
    23221 tgtcctttaa tcatatggct catttcagat aagttcgctt catttacttc caaacgtaaa
    23281 tgagtcaaaa tcttttctcg ctcactgtct tcatcaaaag cgaagacaac accaaaattc
    23341 cctttttctt tatctgaacc taagtcgcca ataaattgtg tatctagcac taattgattc
    23401 atctgtgaac gccccacacg cgccattgct gcaataatac tacgtcccgc gttcgaatta
    23461 ttaaataccc atgcttctgt aaaataaatc gctgttttct tactactatc tcgttttcca
    23521 aacatttcac aaaaacgacc taaactaatc atcaaacaca aagactttcg atccgcatct
    23581 gtatatagtt ctggtcggac attgtcattt ggtaatttca aatcttggat ctctaaaatc
    23641 gttgttttgg cattaaagtc taatcccggg ttttctccat aagaaaatcc taaacgtaaa
    23701 atcgaatctt ctaccgtcaa gcgtaaaaac tcaccatatt ctcgaacctc tttttgttcc
    23761 atttgttcta aatactcgac cacatgcatc aagccaactt gttgtccggc ttctttttga
    23821 actaaaactt cttggattcc ctttaatacc gcccctttta aaaggtgatt ggtacctaac
    23881 ggacttaact catcaatcat atcctgggct acttgtttcg catctactcg ggataaacaa
    23941 acaattggat ctaatacgcc ataattacgg ggatttgtag catctaacgt gacataactc
    24001 attttttgca aatgttccac aaacaaaggg taatgtttct gataatacgg gtcttgaatg
    24061 agtttcgtaa accatttgcg cttttctcct ttgggatcca caaataaact ttgtacattc
    24121 ataaacgaac tatacaaaaa gagcaatcca actaaaaagg tcttcccttt accggttttt
    24181 ccagttactg ctacatgagg cgcatcaaac aacgcacctt tgattccttc cgcaatagct
    24241 agaagattca aaaagacaaa acgatttgac gcataaatta attcttctaa tggtgttttt
    24301 tctcctcgag aaccaccatc ccctaatgta tcttgccgac caatatacca gccggattcc
    24361 atacctaatt ctgatactgc tgaaaacaac cattcgccaa ttgcttctac agttgttcgg
    24421 tgcttccaat gcaactgtcg acccaatggt tgccctaata aacatttata gaacaattct
    24481 cgttgatcat tttttgcacg gtggatatgg atagtcgtat gaagctgttg aataatcgtt
    24541 gcactatttt gacgaacttc ttcaaccgtt tgaccgtata caataaaaca tgcgatccaa
    24601 tcgacgacag gttggccatt atctactcgt tgctttaaat gttttactaa tccccgaaca
    24661 gttaataagc gttcgctagg ttcttcatcg ttttgaacca attccttata ttctgttttg
    24721 aaccgttccg atagccaatt tagttttaaa ccaatacctc cctgtccttt caagcgtgga
    24781 tagtgaattt tcattcgtaa ttctgctggg aaagaaagat cctgtgcaaa ttgaaataga
    24841 tcacagtttc tcatattttc aggtgtttct ccaataggta acaacgctaa ataactagtc
    24901 cccaactcat cttctaattg aagaaggcct ttatgttcct tcggcatacg tacatacgtt
    24961 ccttgattgt ctttcagtac ttcccaatta ttttgttctt ctactttatg agccattcct
    25021 cgaatatatt gcagacgatt gagatacaac agctcttttt ttactaaggg acgaatagaa
    25081 aagctataaa gtaattgtgt cacttctttt acataaggat cactttcaga aaacaaagtt
    25141 tctaaatcat ctacttctaa tccaaataag cgtgctaaac ttcctgctac atctaaccag
    25201 attagattta gtacatcata aaaactctcc acggttgctt tttctttgac tttgattcct
    25261 aaaataaagg aaggacgata gacttgacct tctcgttcca acaatgtcac tgtttctttt
    25321 gcataatacg caccaattgc ttgactatcg ggagaaaatc cctttcctaa tgtgtcaaat
    25381 ttcgtccgta aattcattgt tcgtggatac atcaccaact ccacatcttc ataatctgct
    25441 aaaagtaaca gtaaacgagc catcatttct tttatttcct gtgtcttttt tggtgtgttt
    25501 tttgaaatgg ttcgtggaaa aacatgatag taggcccaga tacaatcctc gccatttaac
    25561 aaacaatttt tctttaatgc tttcactggt tcttttacaa gtaccaatag atctcacctc
    25621 ccaattaaaa aaaggaacaa ccagttgatt gtcccttttt ctaatcctct aaataaacat
    25681 acttattcgc aaaaagtaat tcttccaatg cattatttga taccttgtcc cagttataat
    25741 acacacaatc accattcatc atacgcacta cataacaaaa ccaatcccat aaataaaaat
    25801 gcactttttt tccatcaggt tttagttttg ccagtgctaa cacacataaa tagggtagcc
    25861 ctataaaaaa aacaacccct gctggtggaa aaaaagaaat aacccaacca ataaatgaac
    25921 gtaaaaataa atattcaaag attacgacca ataaaaaagt tgctgcattg actaatgcaa
    25981 ctggaaatgg aagacgccaa ttgcttgtaa tctgttgtac gcgataaggc tccgcataaa
    26041 caatcgaata atcgtaaggt tcccaatcca cttcactatc ctcctaatcc ataaataatt
    26101 tttcaatgat tttaccaaac gcatcaaata cacgcgttgg atcatttaag aagaaataga
    26161 ctgcggcacc tgctgcgata gatattaatg catttcctac ttttgatttc ataaaatttc
    26221 gcaatcccag ataaacaacc accattatta aaaaatagcc accttgcgtt aatataaaat
    26281 ctacaattcc cttcagtgtc atttccgttc gtctcctttc ctatccaacc aattatgtgt
    26341 gagtttttca acataatact gatttgtttt tttcgtaata acaagcgtca tttgttcttt
    26401 ttgtaaaagt gacgtatcac catctcgaaa gacgactgtt gcttttacaa taaaagtttt
    26461 tttcgtttct ttataacgca atactttcat ctctacttga tcaactttag ctgtctgatt
    26521 gagtccttca ggttctttca tcatgtatga catatctttt gcattgtttt tcgcatactt
    26581 atctaagaaa tcttccacaa atccttccac atctttcgct tccgacgcat caaccgtttc
    26641 gtataatgtg tcatcataag taatcattcg ttgtttttct gtattctttg gtagtgccgt
    26701 aaaataagga taagcaataa tacgacagcc cttgtttgaa atagaaaagg gaagattgag
    26761 tacttgtgtg attgtcacac ttgtttcttt cttattctct ggatccatcg agcgaatatc
    26821 ataagttact ttataactag ctgttggaat ggtttcaatt tcttttaatc caataaacga
    26881 agcagcagtt aattttcgaa tacctgaaac acttcctggt tcttgaataa agttttgtgc
    26941 ataaaactct ttttttaata tttcttgacg ttgttgttct tgttcatgat tatcgaatgt
    27001 attcatatac aaagcaacaa aacgattcat aaaggattca atttcaggtg tgtacgttaa
    27061 ttctgactga ctttgtactt ctttcttttg taattgttgg atttcatctt tcaaaaacga
    27121 cacttgaacc ttcgttttca tggattgaaa aaatgccaag ccccctgaaa aacaaagaaa
    27181 taaaaccaaa caccaaatcc atttcactgc tttttttgaa tggattttcc tttgattcgg
    27241 tactttctct gtataaactt tttctttccg ccgtagttgt cgttttttca taagctactc
    27301 cttctagtat gtttttacta gtacgtacga ttgacaacga taagcttgtt tttctgaaaa
    27361 atagtccatt caattaccct cattttctat tccttttctc tttcttttat atccaacaaa
    27421 tccagcaata cttgtcaaca ctcctcctag aacagaaagt acaacatgta tttcttcacc
    27481 agtctttggt aagacttttg tttttccatc tgctgttttg acttcaatat tgccacttgg
    27541 aagtttcttt acaggaatcg acaaatcctt taccaaattc ccttcactat cttggattaa
    27601 tggaattcca tcttttacac caacaattgt ttgtccacct tctgctttta gtggagttgt
    27661 tggtgttgga atatgggtca attcctctac attactagtg acaatcggta cactcattcc
    27721 ttgagaatta ttcgtcgtaa tttcaccgtt tggggttacc gatactgtga cttcttttgc
    27781 tggaacaata ggtttatttt cttttggaat tgcttctgat ttttcagcag gttgtttcgg
    27841 ttcttctttt ggttcttcac tggtaaacga catcgttggc tgttccgtac ttgacgaatc
    27901 ggtattcgtt tcagaagaac tggttgttcc tgattgttct ggagttgtga ctatacttga
    27961 atccgttgtt gttgaactgt gcacaccttc ttcttcaatt ggatcagtcg gcaaagttga
    28021 ttcaggaatc tctggttctg gtgccactgg ctctttttca ggtttctctg gctgcaaatg
    28081 ttcaggttct gctggttttt ccgttgttcc tccatttagc tctgtctcaa catctgataa
    28141 tccttcccct ggcaatgttt ctacaatttc tgacttaggt gtttctacag tttcatctgc
    28201 ataaaccaat gaactcccta attgaaacga aaataatgaa attcctagtg ttgttacgac
    28261 tgctaatgtt gtttttttca tgattattcc tccaattttt tatgcaattc gtgttttgtt
    28321 catagacgcc gcactaatat tatctgaacg ataaaagaac tcccgtccgt tttcttctaa
    28381 cccaacatat ggattatttt tgaataattg aatcaatagt tcactggtgt tgtattttgg
    28441 atagtttgca aaaaaataat actgtgcttg tcgcccatcc gaaaattcaa caagtaattc
    28501 ataacgatac cgcttcaatc cttttcgttg ttttaaagga tctctatacc aacttgtcca
    28561 tcgttccgtt cgtggaccga gatagacacg atacacatag aacaatgcca taccacatac
    28621 caccaaaaat aataatcgcc acataaaaat tccccctttt cttctacctt tcttgaatca
    28681 ccgaacattc ataccctcgg tagagatccg aaaaatccat cattaatttt tcgtataaac
    28741 gttgttgcaa atagcgattg tttcgaatac ataattcttc atagccatca atcacttgat
    28801 cttctttctc atagcatctt gtagctctat gacgctcagc ttgcatgaca taaccaaact
    28861 ctgcaccata tcgttctacc gttaataact gttgactacg caataatgca atataacaat
    28921 cacaaaaatg ttcagccgac atttgatttt tctcacgttt gtgaaatagg tattctttag
    28981 aaagcacatt attcgttaaa caatctgata aatagcgata atctggcggt cggttatttt
    29041 catctgtgaa tttttcccat aataaactga tttttattcg ttcagcggct agatagtctt
    29101 gttcgcgtgg ataaaattca tcaatcgtac aaagcttttt tatcacccga ataaacaaat
    29161 ccatataatg cgaaacgaac tcttcctttt caattggctc tcctaaaaat tccagtgaca
    29221 taccatcttc tccttcctta aaaaataaaa aagcagaaac cgatttggct tctacttttc
    29281 tttcctttta tagctctttt ttacggaaga atccgcaaat gacatttttt caaaaaatta
    29341 atcggcacaa gttcacgaaa acttggagca attttagata gaatcacttc cccatcttgt
    29401 aaaatacaat cataaaaatc atcagttact tgatacttac gcttcttaca ataattgata
    29461 aaatagtagc gatcattttc tatttccatt cgttgttcta ctaagcgcat acgaacatca
    29521 tcatagaaat aagccacaaa tcgcccttca agttcacgtt tttcaatggg atactctttt
    29581 ggtaacaatc tattttttcg tcgtttatac attgctggat accttagaag aagttcatcc
    29641 aaacgtctgt cagtatatgg caactgacga atcaatgatt ccaatcgttc tttatacaga
    29701 tagaataatt ggcgcaagca atagtgtact gcttctggat tttctaatac tgttggatca
    29761 cgcgaccaat acgcaccaac ataaatcata atttttttca tttagacaat cacaccagca
    29821 atactaatca ccgatccaca ataggtagaa caagtggcat agcggccgat ttcctctaat
    29881 tccagctcaa tctcttctaa agaaagatac gtctgttctt ctgttggctg gcgattcatt
    29941 tcccaagtaa cagttgccaa cgagatttct tccacaagag gtttttcgtt gctaagtgct
    30001 gccacacagt tttcgtatat cttcatttta tcgcagcctt tttttaccgc taaaatcgca
    30061 ggtaccggca atgaaaatcg ataaaagcga atgaatttta gcgttccttt tcttcggcta
    30121 aattccaact cttcgagttc ttgttcgtac cccttacgaa cttctaataa gcgtgcaatt
    30181 tcttgccagt tttctttttc ctgataacgt ccagccttta ccgcttgttc aatataagga
    30241 actcgaaaac gaaaataaga caaatcaacc atcttttcat ttaatgcttc aattgcagcc
    30301 tttaaatcca aaagacgcag ccattctgtt gtcgtatatg cattcatgca attttccctc
    30361 ctgacgttcc catccattct agatagcttt gttgctcgtc atttagttca gcattctcaa
    30421 ttccttcttg tacaaagtct cttcctaaaa tacgatctgc ttcttgtaat aactttaatg
    30481 tcggagctac ttgtttcaaa aaccagcgtt ctgaacgatc taatgagaat ttttctggct
    30541 ttacggtaaa atccaattct tccatcgaac gaaacaattt tgcccatcgt tcatcaacaa
    30601 ttcgtgcatc actttccagt cgatcccaaa caataagttt tgcattaatt aaaccaacgc
    30661 caatctctcc taaacgttta ggggaatgat ccaaaataaa cgcttctact gcttgtgttg
    30721 ctttttcatt agctaggcgt aactcatatc gattataaat gccatatttc gttaatgctt
    30781 ctatttctga aattttctca cgattcgcaa tttcaaaacg tttttcgtag aaattgaaaa
    30841 acaatggact ctttcgcgat ccaaaataca aggataaccc ttcgcttcgg aaataaccat
    30901 catctaaaaa acaaccgcca atattctgaa atttcttaaa gtccatttct aataaacctg
    30961 ctttttgttt ttctagtaat tcaaagagat caaaatgttc ttctgtttcc aatccccaaa
    31021 gttcatctaa cgcaatatcg aatcgactac attgtactcg tttataacca gcttccaact
    31081 ttccttgatt tttccaaatg gaatatagcc atgttcgcca atctgttcgt tgttcacgca
    31141 tgacttcctc atattctcgg caaccttgac ccgaaaactg tacaagtaca ttttgtgtta
    31201 cagtttgttt tgaatgccag aatacccaga tatttccacg aacagaaaga caatcaaaaa
    31261 gatacaagcc cgtcggacgt gtttcaaatt ctgttagatc cattcgtaac acacgttgaa
    31321 tcactatttt gtagtctgtc ccaaaaaagg agagacgcaa atagtcgatc attgctcgaa
    31381 gatctattcc gcttttcata tacaatcgaa agcgttcctt gattcgtttt tcgaaatcct
    31441 ctgggatttt cttttttcct tgttccatct tctttatata atctaccgag catcccaata
    31501 actgtgcaaa acgtttttga gagagtaatt ttttccctcc acctgaagcg tgaatagcac
    31561 tcaatttttt tcgataattt cgcaattcaa taggtgtcat attctacctc ctttataaaa
    31621 taacaaattt cgattttctt aatctgctag aaatcccgat ataacaggtg gtacccccta
    31681 atttttctaa aaaggagtac tccttctaac cttagctaaa gccttgatat aactgattta
    31741 aatacacttt tttatttgtg ttatgttatt tctgcccccc atattatata tcggggggct
    31801 ttacacaaag aggccgtgcg caagcgcacg acctctttgt gggcacacat gccaagcatg
    31861 tgctgccacg actggtctcg gtggcttcgc cgacacaagc cgcggcagca catactcgga
    31921 caatgtgttc tcccatagtc cctatgaaag ccaccccgat atctaaacca atgaatcttc
    31981 tttttcttgt aattctttat actgttcagg agcaaaacac tgtaaaatcg ctaaacgtaa
    32041 ctgtatgttt ttctctttgc ataaccgata tacctgacga aaacgcaata tatcctcttt
    32101 tgtcaaaaca atctgatttc tcgtaacaaa caatgtctcg cgctcaattc gtcggaaaac
    32161 ataagaacct tttgtgtagt attctacttt gttaatccac tcgtataatc ttcgaaccgc
    32221 aaaatcaggt gaaatttcac ccgcagctga agaaacacga tacaaaactt cacccatact
    32281 tcaccacttc cttctaaatt ataaaagtgt ataactttcc tcatctaccc catttgtttt
    32341 cgtatttcct tttaacgatt gcgcttgacg atcaatttgt tcttcgtaac tagtaaacgc
    32401 ctcttctttc agtacagaaa aatcttgcac aatcattgtg tcaaattttt taaattcctc
    32461 aataaagtga tagtctttgt aaacaaatgg cgcaaagaat tctacaggca catcaaaacc
    32521 aggaaaagca tacccacgac caggttgatc tttgttataa aacggcttat tcttaaaatc
    32581 ctctccaaaa gtcattaaat agccaatggg agataaacgg ccaacagaaa tacggaacgt
    32641 taaactatct cgaacaccac ttggaaaata ttccgcatct ggtcgctgca tcgctaaaat
    32701 aacatacatg cctgcttgac gaccttttaa tactaatggc tgaattaatt tatcaacttt
    32761 gtttctcgtt tccatatcca acgaaccata gaaagctgcc cattcatcaa aaaagataaa
    32821 atgcggcggt atcccataat aagcataatt tttccctggt tcatacttag gctctttcat
    32881 cgttttcata taggtatatc gctgattcat ttcttgtaac gcatttcgta agcaaataat
    32941 catttcttca ttcgttttgt aaaacacatg tcctttgaat acatcaatat cacctaatgc
    33001 cgctaaatct gccgctttcc catcgcaaat atctactgtc cctacatcta aacaagcttt
    33061 gatcaatgaa tacaataaat aggtttttcc gccaccaatc gcaccagaaa ttaatagatt
    33121 tggcgattga tcatataccc aatccaatgt tttcattaaa tgaatacgtc cattttctgc
    33181 tatacattga tcaataggaa tccgaccaga atcggaaaga aatacataat tgattcgggc
    33241 tttttctcgt tcttcacgaa ttaaatcacg caaaaatact tcggataata agctacccat
    33301 ttttaaaaat cgttcgtgga aacggccacc atctaaagga aaagaaacca ctaattcttg
    33361 tttcttttga taaaaataaa cttttggtaa tctcattttt tccttcgttt gtttctcacc
    33421 aacttgcttc tttgtataaa caaaccgatt gtcaattaac attcgagcaa gtaactgacg
    33481 ccaataaaca gaagcaaaat atccttcctt tagtcgcgac caacgcatca aacctaaaat
    33541 taatccacta accagcaaca aatacatcac aatactgatt ccaggaataa gatacatttg
    33601 ccaattcgaa tacgtattta aacgaggata aaatactttc caactaaacc aacttaatag
    33661 aatcaaaaat ggtaacagaa agaaaccata ataacaaaac cataaataac gattgaaata
    33721 acgaattcgt cgaccacgat acttaaaaaa atgaggttcc aattgtcaca ttcctccttt
    33781 ctgtttttac ttctcctgtg ctaaaaattt ttgacaaaaa gcaactaata ctggaatatc
    33841 acatttaata aaaaaccata atcgaaaaag atttaatcga tttttatatg ggtgtgcaca
    33901 catattacat attcgtacta cacgaatcca aaccacttcc tgatggtctt gtttccactg
    33961 atacggtaat gaaaaacgaa caagatcacg taaaaacata cactgcccaa taaccgcaca
    34021 aatatactca tttgtttgta taaaaatcgt tggattgtct ccaaaatact caatcaattg
    34081 ttggatattt tgacaacaaa ccataatctc tcgaagtgtt tgattggttt tgtccagatt
    34141 caaaatctcc ccttccttct accttaaata gaaagagtag gaagacttcc tcctactctt
    34201 taaaaaactt attttttctc tttttcctta gaatcagcac ttggttgttt ttgatctaaa
    34261 cctttttctt gtgattgttt cggattagaa ttatttgttg gagcttctac tttctctaat
    34321 cctttcgcat aaatcactaa atctgaatat tcacgattgc catcttgtgc tggaatatat
    34381 accacatgat attctggatc aattaatttc acaggatcac gtcgtttaaa accagtcaaa
    34441 tctacatctg ctggaaattt aactcgtcgt gcaatctttg gttcatctgg atttccaaaa
    34501 actaattgtg ctcgctgtga tcgaatttct cccgtataat cgcctgtttc attatcaaat
    34561 acacgatcgg actcttctaa tgcgccaaag cgtacggctc ctatacaagt ttcatctaat
    34621 gcttctgtaa tatcataatt atttggaaat tttaatccca tcttacaaaa cctcctcaat
    34681 ttttacacca gttaaaaaga caccgacatc ttgatagcca gttgttcgac gctctgtttg
    34741 tcccatatca tttgtttcac gactattcac tctttcttta cgaaaaacaa aataagcttc
    34801 ttcaaatgaa atacgtacct ctttttctgg taatcgtaat cttttatcct cttcagctgt
    34861 gagataaaca aaaaaagcag gctgttcttc tcgcgaacat tctgcttgta attgaacata
    34921 tcgcccagac acaccattaa tttcctttgg tggattaggt tcccgtgaac ccaataaaaa
    34981 tacctgacct aaaaactctt tcttcatacg caatgctttt tctgccatat catttttcct
    35041 cctcttaaaa ttcacaatca attctaaacg actctatatt acacaatgga aagtaatgtt
    35101 taacaacaaa tggctcatca ctaggagaca tatctactat taacatcccg tctcgttcat
    35161 gcacagaaat atcagtacac tcctcatacg tacattcttt tccactcaaa aaacaaatat
    35221 ttatattttt cttttccata ttcttttttc ctccattatt ttcttttctg taaaaaccaa
    35281 gtaataattc cttttccatc ttccaacaca aactgatgat atatttccct agcaagaatc
    35341 cacacacatg ctaaaataaa gaaaataata atactactaa agatgcactc atccttgctg
    35401 tcaaacggaa aaagatatat cataattgcc tcccccataa ttaagaaacc aattgataca
    35461 aacaaaaact ctaccatcat acaaaagaat atttcttcca actcttttac atcctttcta
    35521 actttttata aaaaaggaga ttatttttat aaacactttt attcaacaac tattttcaaa
    35581 tgaattacac attatcatct caagtatagt ttcaatcgtc actattgttt ggtccatttc
    35641 tagcttttat ttaaaacatc gctatacaag aaaaaagaaa agcactgaaa ccctaacaaa
    35701 agaaatgttt attccattta aatcttcaat tgaaaattat ctatttcaaa aaattacaag
    35761 aaaaaatatt ctagaacgaa aacaaacaat tcaacatcta atccaaacag ttgaaaataa
    35821 aaatatagac ttttatttgc cttatgaact tatttatttt gccaaagaaa tacaaaaaat
    35881 aattaacaca aataaacatt cgaaaaaaat cctcttcaaa gtacaaagaa tgtattttga
    35941 attctcatac tgctacctag cagaactaaa taaagtaaga aagcaattag gagtagctaa
    36001 acgtgatttc ttctatagaa aaaaagaaac tgtattatca cataattata ttctatctct
    36061 tttggatcct taaattctta tttattacac tcagtatttc ttggtgtatc ctcatgatca
    36121 tttactactc aacacaataa tttatttgcc tttgataaaa aattctttct aaaaactaaa
    36181 caagcggcta gttgcctaac cgcttgttcg tcctctttag tctctgactt tatacaaatc
    36241 ataaccaatc aatcctgccg caaggacaaa gatcatacca atcatgatcc ataatacatt
    36301 gtcttcagag cctgtttttg gcaacatagg taccattgca gcttgtttca cttcttttac
    36361 aggttgtggt tcgtttggtt ttactggttg cggtggtttt ggtgcctcca caaattgaac
    36421 cgtttgatct ttgtttgtta gatcgacgtt atgttttgcg acttcttcaa acgtttcttt
    36481 ttcatcttct gttttggctt ggagccattc cgcaaaactc aatccttttc ctgcaaggtt
    36541 gcgaccgtca acgatgaatt caaacaagaa ttccatcatt tctttatcag ccataaagac
    36601 tttttccgca tgtgttcctt caaatggggt gccgtctggt gttaagtagc cttgaacaat
    36661 cagtttgtaa atttgaccga ttgctaaccc attaacttga acccattcga caaccttttg
    36721 atttggtaaa gctaagatct cttttccacc atttgcattg gtagcttttg tcgtaatggt
    36781 tggactgacg attttgatgg tttggtcttt gtcggtaata tctgcgtgag aagccaataa
    36841 tacgccttct ctaaacagat cttcaaaaac tacgacttct ttgcttcgca acgcatgtgc
    36901 gtctaggata aagtctagat tgactgtacc atcagttgtt tctgccacaa acgttaaggt
    36961 acttgagact tcttttccat ctactagcac tggtttttcc gttactttgt ccattagaac
    37021 accgttgact gtgtatgttt ttccaacgat caaatcgtgg tatttcacag cgtctgtaat
    37081 ggtgactttc gttaatggat taacctcttt caagccagtg ggtttatgtg tagccgttgt
    37141 acgtacactt gggttcgtta ctcgtaccgt ttgacctttg tcgttgatgt ctttatggtt
    37201 tgctagttct tcgtcatttc taaaaagact ttcaaacacg accatttcac gaccatttaa
    37261 acctgtcaaa tcaaaggtaa atggtacgat caccgtttca ttttctgctt tggcaataaa
    37321 gccaacagca ctttctaccg gttgaccatg aacaagtaag gcttcaccag ttgctttatc
    37381 cattaagatt cctttgacca agtaagcttt tcctggaagg atctcattaa tttcaacggt
    37441 atcatttaag gtgaacagcc ccgttgggtc tgcgatcgtc aacccgtctt caaatacagc
    37501 tgtggtatga accgttggat tgtttacccg aacactttga ttgtcatcat tgatatccac
    37561 atgtaccgca acttcaatgc catcacggaa aagtttttca aagacaacga ttgtttgacc
    37621 tttcagaaca ctagcattaa ccacaaattc aagatctttt gtgccattgg ctttgtctgc
    37681 aataaaggtc aagatacttg tgatttcttt gccttcttgt aaaattggcg cattcgttgc
    37741 cttgttcatc aatacacctg aaatagtgta ttctttgccg acaaacaggt tggtataaga
    37801 aacactatct ttaatgacga tagtttctaa tggatcaacc actttttcac catcggcttt
    37861 atttgacgct tgtgtttcta attttggtgg aatcaaatag ttacgtacag aaaccaataa
    37921 cgtttcccca tcatctggcg cattttgtct gaatgtaata gtgaatgctt gtttgcctgt
    37981 atttggttgg aaactttcta atggtacatt ttcggtaaag taatagttat tggcaaccag
    38041 accttttact aaaatctcac cattttgatc ggtggtatat ttaccaattg cttgaccttt
    38101 tccgttatat agcgtaaacg tcacaccggc aagtggtgtt ttcttcttgt tccattcttc
    38161 atacttgaac aattttacac ttttccgtgc ttgacggttc gcaaaatgga tcactttgat
    38221 cggttctgta tcattggtaa tcgagaacac taatgggttt tgattcaaaa cgtaatttac
    38281 gggtgctttg atttcttcca aacgatagcg ctcttttcca taagtaagtg taccgttagt
    38341 taggaaaaag cctttttcat tggttttaaa gatatccgtt gtttctgtat catttggaat
    38401 ctccattgtg acataacgat tggctaaagt atcaaaaatc ttgaattctg tattggcaag
    38461 tggaatcact tttcctgttt cttgatccac tttcaccact ttaagacgtt gttcaattac
    38521 tttatcttct aaaacataat ggaaagtttg cccattttca gaaattgtga cttcaagtgg
    38581 ttcaaatagt ttataccctt cttttccttt ggtttcagaa agaatgtagg tatcaaagac
    38641 aacagtattt ttaccaaaag tagcgtaacc atcattgtct gtcacaacgg ttttcaccac
    38701 tttgccagtt gtttttgacg tcaaagagat ttcaatgcca gctaattttg gtttgttatc
    38761 tggattggtt gaatcgacta aatctttatt agcaattttc actaaatcaa tggttccttt
    38821 gatcacttga tcttttgcgg tcgcattgac agtttttcct ggttcaacaa caatttcaat
    38881 tgtttcatca gaaagtgcat agcctttcgg cgctttgatt tcttttaaaa catatttgcc
    38941 aggatcaaga tctttaattt ctgcctgtac tttgccgttc atatttttca aggtaatttc
    39001 tttgatcttt ttcccatctg cttgatacaa gccatacacc gcattttcta aagaagctgc
    39061 gccttgtgct ttcacaccgg tttctgcatc ttctttaaag acacgaatgt ttccctgttt
    39121 caaaatagtc aaattgacaa cagagtcacc aggttcaaaa ggattcaata taccaattgt
    39181 ttgggcacct ggacgacgat acgctaatgg cgtacccaat acttcaatct gattgaaatg
    39241 aatttttgcc ttttctggtg cttcttttgt gactgtgatc catgcttcat tcccatgaat
    39301 agatacattg atcccttttg gcttttgaat gccttttaca cgttgtagaa agtcattgcc
    39361 actttttact tttaacgttt cgccaatttt tatcgtatgt gtttgattat gaaaagtagc
    39421 tcttacatca aaattattaa gcagacgttg aatttctgct tttcgacgat cataatcaac
    39481 acggatattt ttgattggga tttttgtgcc caaagcttcc caaatcataa attgtgccgc
    39541 aatgtattgt tcatcggatt tgtctttatt tgtgacatat cctaaataag agatcaagct
    39601 tgtttttttc cgtacatttg aatttttcaa atagttttcc aaagcagtag ctgtataaac
    39661 ttgaccttct gcggctgaga caccaggctc aatacaaaac gccacttgtc cattaatctc
    39721 aaaacgaacc atataattta aagtgaagtt tggattgttc ggactagaag taacaccaat
    39781 attttcgccc caatcaattt tccgaccacc taaaacagct gtattggttg cacggcgaac
    39841 acgaaccgaa cgattggttg gtactgttac taacagtgta ggtgtacctg tttttggaat
    39901 gtcctgctct tttttctttt gatcttcaat actagccgta gattctttgt ttagtttcgt
    39961 tggttgattt tgactagctg cggttgaaga gattgttttt tcaacgtttt cctcattttt
    40021 tccttctttg tcagcagtag ccgctggttg ttccactgtt tcttctattc gttgcttttc
    40081 ttccgcttgt ttctcagaag actctggctt cacagaaggc gttgcttcgg cagctttttc
    40141 tccttctgga gtggacgttt ctgaagcagg ggttgtaatt gaggcagttt cttcaactgg
    40201 ttgtgaagta acaggactat tccctgggtg ttgtgtttcc ccaatcgtct gatcgagagt
    40261 cgttttggaa ttaaccgttg gcgcttctgt cacaggggcc tgttcaacag tggcttcacc
    40321 agctgggacc ccggcttctg ctggttggac ttctgtcact tcagaagcga cttgggcaat
    40381 ggcttccacc gtaggttgtg tagccgtcgt ttcttctgca tgtgcttgag cagttcccac
    40441 caagaaacag aattgagata aggccaccaa tgcgagtgct ttcaaccaat tcattttcgt
    40501 ttttgcatac acaagaattc ctccttttcc tgagaatttt atataataaa acaaaacacc
    40561 gttaccaaaa gtgataacga cgtgaactgt ctcttctatt tttatctggc gctcttatct
    40621 gaacacattt catcaatgat tttaccctcc cactataatt acagaacaaa aaaagaacct
    40681 gcttcgtgga aatcaactgt ccatttccca attggaatac cagctttatt ggcaacttca
    40741 ccatcaccaa atatcatgcc ataccaatta ctaccttcat ccttaatttc tttccaacca
    40801 tatgacatag cttcatctaa cgaatcaaaa atcatgccac tgttgccaat tgttgcagga
    40861 tctggcttaa gatcttctgg aatagaaata tcaatcacac cataatgatc cgattcccca
    40921 gtattattgt cattactagc tactggtttg gttgttctac tgacttattt tgatacaaca
    40981 agtacgctta ttcttctttt acttctccgt tttcaatttc ccattcaaac cactccgcaa
    41041 agtcttgctt aaaaccatct actcgatacc tattttgtaa ataggcatct tctgacgtcg
    41101 taggatctaa ataggtaggt ttattctctg gacgagcata gacacctacc catgtttcgt
    41161 aatctccttc aaaataacta tctaccaaat agcctttttt tctaagaatc tcccgaactt
    41221 gatttttaat tattgatact tgttcaaaac catcactcat tctatcacct caaataactc
    41281 tagattctca taaatattcc cgacaatttc aatcctatca atgatctcta acaaatcgct
    41341 acttatgctt ccccattcgt ataagaattt cccttccgca aaataaattt tccataaact
    41401 tcttcatgat cgtcccaacc aatatcactc tcgacaaatt ccacgttgtt cttatctttt
    41461 agctcagtaa atgccataag ttcaacatgt tttccaacct cgaaacaatc acaccaccca
    41521 tcaaccgtta cacgtgtgcc ttcaatacct aagaaacttt gtcctcgtgt attaaacact
    41581 aaaactttcc gcattttttg ctcattaatt aatcacgcgc gaaatctagg aatcacaact
    41641 tgttcgcttc ttctttataa aataaaaaaa ctccaataat cggaaattac tatcttttcc
    41701 tcattccttt tttaaatctt catacttctt cttatctttg tcctaaccta ataacacaaa
    41761 ttttgaagaa aaactcagta aaacctgatt ctttttttat cttcacaaca accaactttt
    41821 tcttcagatc cttttactag aacttgtata caaaaattgt tgaatgctga tacaatttgc
    41881 ggttacttga aaaaacgata gatgtaaaaa gataaataga atcatttttt tattctatat
    41941 cagtctatga ttcattgctt atcaatcacc caacccattc gatgccgttt ttttaagaga
    42001 aatttaaaaa agaccgtacg aatctcgcat tgtccgatta cttttctaga aaagatcccc
    42061 aattctgtat aaataaccct atcttcttgt tggtttcatt ttctcatata agaattcagt
    42121 caatctaccc actatgacca ttactacgtc caacacaacc gacatattaa ccacgtaagt
    42181 attccctcac agatctccga atttccatgg tatggattcc catcctgacg ctgcagagga
    42241 caacatattt catgtggctc tgtacccttt tgatttggaa agactacaaa tcaatactca
    42301 tctataactt atcaagcgaa ctttcgctag gcttctagtg attactaaat tgttggataa
    42361 catacctagc ccattttatc tagctggtat tcataacagt tatttcttgt attacttctt
    42421 ccgcttgtgt tgccattgag cttgtcaaaa agttacttag aaaaaagctg ccagtaaagc
    42481 aactttcaac aaaccctttt tgtttcttat catatcaaga aacctccttt tataaatttt
    42541 tctataataa aaaaacgtcg ataacttaat aagtatcgac gtaaactatt tttatatccc
    42601 gtaaatcaaa aattctaaag aaagatttcc tatataagca tattggataa ttcgattagt
    42661 attgggtata tctctaccat tctcatacct atctatggac cattttgaaa ttgaaggaga
    42721 aaaaagcttt ccaaactcct ccctttctag ataataatct ttcctaattt tcctcatcct
    42781 taatcccata ctaaaagaat ttatcttgtt aaaatcgcta actctttcat cttttggaag
    42841 tatattctta taatcttctc cgtacataag gtaaggaaca gtgaccttac caagataggc
    42901 aatattcatt agtttttcaa tatctggaat attaatacct ttttcccatc tacttataac
    42961 atttttgcct gtatagatgg taaagttttt accaaatttt tcaagcgtct cttcccggtt
    43021 ctttcggact tctcgtattc tttttcccat aacaatttta tcgtcttttg ataaactaaa
    43081 tatctcacta tcacgattac tctccttcga aatttctttt tcattactta atagaaaaat
    43141 atcgattttt ttttgcattt cttttgacgg atttctcttt ctatttaaca cataactgag
    43201 taatacttca ctaattccta tattatcagc taactctttg ttaagtaact tattcatatc
    43261 tctgtatgca attagttgac cgatgagaat ctcaatctta tcttcctcat cttttattag
    43321 agtttctata ttcaaaatct tgcttagagt attatctacg tctttaggga tttttcttga
    43381 ccctttttca tatttaacta aagtactttg tgaaatacct gctaaatcag ctaacttttt
    43441 ttgagatagt tttttctctt ttcttagaga tttaagaacc cttccacttg aattatcaac
    43501 catgaaaaaa gcacctccta tgagatgctt tcatcatata ctgacagcta aaaatcttca
    43561 agaaaaaata ttccaatttt gttaatttta gtatcgccgt gataaccaaa tgacagttta
    43621 aaatctttta tacagataat cctcagtgtt gcatctactc aaaaaggttg atttaatagg
    43681 tttttcgatt gattataagt tatttcacac tatcttgctc atccattttc agaacggcca
    43741 tgaaggcttc ttgcggaact tcgacggagc cgatttgttt catccgcttc ttcccttctt
    43801 tttgtttctc taagagttta cgtttacgag aaacatctcc accataacat ttagccaaga
    43861 cgtttttacg caaggctttg atgtctgaac gggcaacgat tttttgtcca atagctgctt
    43921 ggattggcac ctcaaattgt tggcgtggga ttagtttttt cagtttttca acgattgctt
    43981 ttccacgttc ataggcaaag tctcggtgaa cgataaagct taatgcatcg actttttctc
    44041 cattcagcaa gatgtccatc ttcactaact tgcttttttg ataaccagac atttcataat
    44101 ccaatgaggc atagcctttc gtgcttgatt tcaatttgtc gaaaaagtca aagacaattt
    44161 cagaaagcgg aatattatag acgacattta ctcggtaatc atctaaataa tccatcgtaa
    44221 tgaattctcc ccgttttcgt tgagaaagtt ccattactgc accgacaaaa tcatttggga
    44281 ccatgatctg tgctttgacg aatggttctt ctacatcctg aatcgttaca ggttcaggaa
    44341 aatctgccgg gttatctact gtagcagtcg taccatccgt tttattaaca tggtaaataa
    44401 cggatggtgc agtcgtgatc aattctagat tgaattcccg ttccaagcgt tcttggacga
    44461 catccatatg aagaagtccg aggaatccac agcggaaccc aaaacctaat gcttgagagg
    44521 tttctggttc gaattgtaaa gcagcatcat tcaattgcag tttttctaaa gcttcccgca
    44581 aatcgttgta acgagaagta tcaattggat aaagaccaca ataaaccatc ggattcattt
    44641 ttcggtaacc tggtaaagct tcagcggcag gattgtctgc taacgttact gtatccccta
    44701 ctcgtgtatc ttggacagtt ttgatacttg ctgtgatata accgacatca ccgaccatca
    44761 aaaagtctct agcaactgct tttggcgaga agaccccgac ctctgtaaca tcaaatgttt
    44821 tgccattact catcagtttg attttgtctc cgggtttgac cataccgtcc gtgatccgga
    44881 catttagaac aacaccgcgg taactatcat aaatagagtc aaagatcaaa gcttttagcg
    44941 gtgcatctaa gtctccactt ggtgcaggaa catattccac gatctgctcg agaatatctt
    45001 caatcccaat ccctgatttg gcactggcta atacagcttc actagcatcg attccgatta
    45061 cgtcttcgat ttcttgacgg acacgttcgg gatctgctgc gggtaggtcg attttattga
    45121 tgactggcag gatctccaaa tcattgtcta acgctaaata aacattggcc aatgtttgtg
    45181 cttcgattcc ttgtgctgca tcgaccacta aaacggcacc ctcacaggca gcaaggcttc
    45241 gagagacttc ataggtgaag tcgacgtgcc ctggggtgtc aatcaagtga aagatatatg
    45301 tttctccatt tttcgctgtg taattgagtt ctacagcatt taatttaatc gtgattccac
    45361 gttcacgttc caaatccatc gagtctaaca gctgatcttg catttcgcga gacgtcacag
    45421 tgtgcgtcat ttctaaaata cgatcggcca atgtagattt cccatggtcg atatgagcga
    45481 tgatcgaaaa attacgaatc tgctcttggc gttctttcat tttctttata tccatagcgt
    45541 ctcctctttt catataatca gcactttcca ttataccaac gaaaagcagt aatttaaaga
    45601 gtttttaatt agtcagctat agaagttttt tttgtagaat tttgctatac tgttatcaag
    45661 ctaataaatg gagatgaaaa aatggatcaa aaagatttta gagaaaatct tgaattaaaa
    45721 ccggtcactc aagaacatat cgatcaattc aatgaattgc tttcctatgt gttccaagtg
    45781 actgaagcag acatcgagga aagcgggttt gagaataaac gagcttttat ccgttccaaa
    45841 aaaccgattt tggaagtatc gaaagtgttc ggatggttcc acgaaaataa actgatctct
    45901 caaatcgcta tctatccttg tgaagtcaat attcacggtg cacgttataa aatgggtggt
    45961 gtgactggag ttggaactta tccagaatat gctaaccatg gattgatgca agatctaatt
    46021 atcgttgcat tggataatat gcgcaagaat aagcaatgga tctcttattt gtatccttac
    46081 agtatcccct actatcggcg taaaggatgg gaaatcatgt ctgataaact ttcctttaaa
    46141 atcagagata cacagctacc taaacaaatc ccagtaagtg gtatggttga gcgattacca
    46201 gttgatcatc cagacgtatt ttccgtttat gacaaatttg cccaacaaaa ccatggtgct
    46261 ttattccgca gtgattttca ttgggaagag tattggcgtt tcgaaaatga agatgagcgc
    46321 acagccgctg tctactacga tagcaaccat gaaccaagag gtgttctgtt ctactgggta
    46381 gctgaagaaa tatttcacgt aaaagaaatg ttctatcttg atcaagaagc tcgaaatggc
    46441 ttatggaact ttatttccgc acatttttcc atgatctact gggtacatgg agatatttat
    46501 aaaaatgagc ctttagcatt tttgattgaa gatagtcaga tcaaagagca gatcgaacca
    46561 tattttatgg ctcggatcgt tgatgtaaaa gaattccttc aacggtttcc gtttgttgga
    46621 acagctgatg cttttcattt catcattgaa gatcctgtcg ctccttggaa taatggtgtc
    46681 ttcgctttaa catgggatga acagggacaa gtccgtgtct taaatgaacc tataggaaaa
    46741 tccgttcgac tggatatcca aacattgact tgcttgatga tgaattatcg ccgtgcttct
    46801 tatttggcaa gaatcgaacg gttagaaaca gatgaagaaa cactgaagtc actagagcgt
    46861 atcattccaa acatggaagc ttactttagc gattattttt gataaaaagg atgatgttta
    46921 gatgaaaatt tattttgccg caccaatgtt tgctaaaagt gatttgttat ataaccaaca
    46981 gttagttaaa gaaatcagag agctctcttc tgagctttcg atctatcttc ctcaagaaaa
    47041 tgaagcaatc aatgacaaaa ctgcttatgc agacagtcga atgattgctc ttgctgacac
    47101 agaaaaagtg ttggctagtg atttaatgat tgctttacta gatgggctga cgatcgatgc
    47161 cggggtagca tcggaaatcg gtgtggctta tgcgaaaggc atcccagtga tcggcttata
    47221 tactgatact cgacagcaag gcggaaccca cccgaaaaaa atcgctgcac tacaagaaac
    47281 agctgaaaat caatttcact acctgaactt atatacaata ggtttgatca aattgaacgg
    47341 aaaagtggtt tcttcagaaa ttgagttgct ttcagaagta aaaagatttt tagatggagg
    47401 gactttcagt gattaaagaa atcaaaaagg tgcaaatagc tttacttgct tttggtgtat
    47461 tcgttgtctg ctataatttt tatgaattta tcacacaaaa atattcgact tctcaaggaa
    47521 tcacatttat cgtggaatct ttattaggga ttgcattgat tttcatgcca caagtcattt
    47581 tgaaagtttt caaacttaaa ataccagcag caatcgtttt gttttactgg tttttcttgt
    47641 tcatctctgt ctttttaggc acagggatgc atttgatcag tatcatctct ttttgggaca
    47701 aaatcttaca tgcggtgagt ccaatggtcc tgacagctct tggctatgga ttgattggtt
    47761 acttgatgaa agatgctgag atatcaaaaa ccagtccttg gttgttcctc ttattcggct
    47821 ttgcgtttgc tggactttgc ggcgtgtttt gggagttctg ggaattctta tgcgaccagt
    47881 tcttaggcat gaatcttcaa cgttttgctg cttctgatgg cacactgttt gtcggacgag
    47941 cagcattgat ggatacgatg ggcgacttgc tgacaaatac gataggtgct gccttaatgg
    48001 gattgtttgc atggtctcaa agtaaaaaag atgagcgtta ctttgaaagt tataaattag
    48061 aaaaagtgaa aaatacctaa taaaagaggt tgtgacagaa gcgggcagct tcaagaaatt
    48121 tcggcttatt tttcgaagaa actacttctg gaacactgtt tatttgaaaa aaggaggtct
    48181 gacactagtt gtgtcagacc ccttttttct tttatagtct caatggaaga ttagacgatt
    48241 tcttctagct cttctgtttt gaaatgaagt tgtccatcaa gtaaagtaat cgttactttt
    48301 gatttaggca taacatgtcc tgcaacgatt tctttagcta gtggtgtttc tacttcctta
    48361 gtgataaatc gtttcaatgg tcttgcacca tatgctggtt cataagcatt ttcagcaatc
    48421 cacgttttgg cttcatcact gattgtcagc aggatttctt gatgttccag acgttgtgcc
    48481 aattgcgcca ccattttgtc aacgattcct ttcacgttgt ctaggctcaa tggtgtaaat
    48541 aaaatcgtgt cgtcgattcg gttcaagaat tctggtttga agtttccacg taatagcgtg
    48601 ttgacttgtt cagccactgc ttctggaatc gttccatcag cagtcacgcc ttccagcagt
    48661 aactgtgaac cgatattgct ggtcatgatc agaaccgtat ttttgaaatc tactactcgc
    48721 ccttttgaat cagtcaagcg tccgtcatct aggacttgta acaagatatt gaagacatcg
    48781 ggatgcgctt tttcgatttc atccaacaag acgattgtat aaggatttcg tctgacagct
    48841 tccgttaatt gaccaccttc ttcgtaacct acatagcctg gaggagctcc gactagacga
    48901 gacacagcat gtttttccat atattcactc atatcgatcc gtaccatatg atcttctgag
    48961 tcaaacaagt tctcagctaa cgctttcgct aattcggttt ttccgacacc agttggtcct
    49021 aggaaaagga aagaacctag aggacgattt gggtcttgca atccagcccg tgaacgaatt
    49081 accgcgtcac tgaccgcatc aactgcttca tcttgaccaa tcactcgttt atgaagtgtt
    49141 tcattcaatt taattagttt ttctcgttca ccttctacaa gtttcgttac ggggataccc
    49201 gttaatctgc caacgacttg agcaatctca ttttcggtaa cggactcttg aaccatctta
    49261 atctcgctgt cttttgcttt agcttctaat tccttcaatt ctttttctaa ttgaggtatc
    49321 gtaccatgac gcaatacagc agcgcgttct aaatcatagt tattttctgc atcttctaat
    49381 tcgtgttttg ctttatcgat ttcagcacgt tttgctgaaa cagaattgac ttcttctttt
    49441 tctgtttccc actgcatctt catcgcattt gcttcttcac gaagttcagc taattcttct
    49501 tgcaaatttt tcaagcgttt tttacttgca tcatctgatt cttttttcag tgcagcttct
    49561 tcgatttcca actgcatcaa acgtctagta acttgatcta attccgttgg catagagttc
    49621 atttctaccc gaatcgttgc actggcttca tcgatcaaat cgattgcttt gtccggtaag
    49681 aaccgatcag taatataacg gtcagataaa gtagctgctg ctactaatgc gttgtcatgg
    49741 atgttaacac catggtggat ctcaaaacgt tcttttaatc cacgcagaat actgatcgta
    49801 tcttccactg ttggttcttt gactaatacc ttttgaaagc gacgttccaa cgctttgtct
    49861 ttttccatat attgacggta ctcatctaaa gttgtggcac cgatcaaatg taattcaccg
    49921 cgagcaagca ttggtttcaa cagatttccg gcatccatac ttccttctgt ttttcctgcc
    49981 cctacgatat tgtggatttc atcgatgaac aagaggatac gtccatcact ttttttgact
    50041 tctttcaaga ctgcttttag tctttcttca aattcaccac ggaattttgc tccagcgatc
    50101 aatgcaccca tatctaatga aaaaatcgtt ttatctttta aattttcagg cacatctttg
    50161 cgtacgatac gttgagcaag cccttcaacg attgccgttt tccctacacc gggttctcct
    50221 atcagaacag gattattttt tgtttttcgt gaaagaatac ggatgacatc acggatttct
    50281 tcatcacgac cgatgattgg atccattttt ccgcttttga cttgctgtac taaatcaacg
    50341 ccgtattttt ctaatgcttt gtattgttct tcttggtttt gtgaggtcac tctttctcct
    50401 cctctcatct cttcgatgtt tttacgcaat tctttttcag ataatccgtt tttattcaaa
    50461 taaacagtta acggataatt ttttaatttc atcaacgcta aaataacgac ttccgttgaa
    50521 agaaactcgt cgccgaagct ttcacgtatt tggtctgctt cattcaataa tcgaaagaaa
    50581 ttctggctga ggttttgtcc atattggacg tttccaccag aaacaactgg atactcatcc
    50641 agtagacgat caatttcatg ttcaaaagat tcgacatcca atccggcatc cgtatagaaa
    50701 tttcgaccaa aatgattagg ttgtaaaaag attttccata catgggcaat gtcgatatct
    50761 tgatgttttc gagtgaccgc aatctgttga gcttcagcaa tcgcttcttg aagcgtcgta
    50821 gtcattttct caatattcat acaggtatac cctcctaatt aaaggtaaga tcacttattt
    50881 ctttgatctt tacaaaaact attatatcgc tttggtcaat tttggtcaaa atatacacat
    50941 ggttttttga ctttttttct cgacttatat aaatcttaaa aaaacaaaat tgattgtatg
    51001 tatataaaaa aagagccaaa caaacgtaaa attatcttat ccataacgtt tttctttgat
    51061 ttgataaaaa gggtagatct tataaaagac ctacccttga ttttctttat tctctttttt
    51121 tacttctatt atttcttctt tgatcactct tcgccgttca gcaatcacat acacaaatcc
    51181 atagagaaat ggcaagataa aggaactgaa acgatacagt aaaagcgaag aaactgcgtc
    51241 aactgttcca acaactggtc tgaataataa caaatagaca aattcaaagg aaccaatacc
    51301 agcaggcgta ggaataaccc ctgaaagcac tactgcaaag ctgataaacg aaatggtcag
    51361 tagaaaatct attttaggat ggttttcaat cagaatcaaa taaggaagta cataccaaaa
    51421 tacaagtttt aacatattcc atagataaat ccgcaatagc gcagtcctgt cttggataat
    51481 ggtttggacc gtttccctta aagagtagat ctgctgattg catgtatcca cccatttccg
    51541 caaacgctca cttttaaata acttattcga taagctgaca aaaaatattt gaacattcaa
    51601 gctgacggac atcgccaata aaaaggcaac aatcacgatc gtcaaaagga taccagcgat
    51661 gataaaccag atcattgatg gaccattaga ataaaaaaga gagaattgga tgaccaagcc
    51721 agctaatgca taagtgatca ctgccagttt gtacataatc atatggagtg ctgtcacccc
    51781 tgctccctgg gatagcttca ttcctttttt gttataaaaa taaatctccg agatcagcgt
    51841 tcctgtacca aacgaaacga ttcggtaaaa cgcaatatag ctagaggtca agaacccatc
    51901 tttcgttgta aaattcggcg cgaaaggttc agcaatttct ttgattgagc gcccttcagc
    51961 gatttggtaa actgtcccta atataacagc cgctgccaaa acaacaacac tggtagacag
    52021 caattcggca aagatatctg caaatgattg attgattaaa taataaataa tggcaaaaat
    52081 cacaatcagc aaaagcagat tcagaatgat tttagttttc gttcctttag acgacatctc
    52141 ctgctcctta atggaaaaaa taaatgagaa tcaaatcaac aagtacacct gcagcgaatc
    52201 ctatagtaaa cttctttttc cgagttttat gatggaaaac ttttcgagag atcaatcctc
    52261 ccaaaccacc gcctaacagg ctgacaaata tcaaattatt ctcaggaaca cgccagccgc
    52321 tagttctagc ctgatgttta tcatacccca tcagacaaaa taagtaaaaa ttcacaatga
    52381 aaaggtaaaa ccacaaaaga ttgtgtaaca atacatccat tactcttctt ccaactttct
    52441 gttaactact atttctaagc tttttcttct ttctttggtg aataaactgt taatcctttt
    52501 gatacaacag ataattcaac tggaagatca tctgtcgtgt ctccatccgt tcgagtgccc
    52561 acagattttt cctgcgcttg gattttcatg cgtttggctg tgaaataagt aatgccgggg
    52621 atcgtataga atttgcctct catgattcta ggcaaataaa aaataaatcg gaaaatatct
    52681 aaggaaggta cgatcgttac atgaaatttt ccatcatcta gggtcgctga gtcgtcaaaa
    52741 tttgtaaaac cgcccacgga gttagacatc gtgactgtca acagttggga ttttcctttc
    52801 caatgctcct cgtctgtttc taaatccaaa tgatattttt tcttcttcag caataactta
    52861 aaaaacttct tgataaagat ccacgagccg taacgctgtt tttcttcttg actgatccaa
    52921 actgctgtat ctgctaagat tccgattgtc agtgtagaga taatgacttc atcattgact
    52981 tgaccatagt ctattttccg tacattgcct tccaggatca cgtcagcagc ttcttctttt
    53041 ttgaggggaa tctcaagaac acgtgcaagg ttgttgacag ttccacctgg aagtaatccg
    53101 acatggtatt gagataatgt tttttggaac gcttggacga tatgatgaat cgtgccgtct
    53161 ccacctataa ttactaaagt atcagcttct atggcttctg ctttcttgac taattccgca
    53221 tcatcaatcg atgggccagt ttcagctagt tctacatata attctggctg cttttctttt
    53281 acataatctt gaaaccagcg tgctaatttc tcaccctcat ctttccctga acttttgtta
    53341 taaaaaacta gcagcttttc cattctttac ctcctattta ctcttcaaaa aagagggcgg
    53401 gacaaccaat tccattgtcc tgccctttag ccttagacag atgacattcc atcattggga
    53461 cgaacgcctt gtcataagct gttctttttc gattttaact ctttgtgttc aattctgcaa
    53521 tttttacaat cacgtctgtt gctttttcca ttacttgtaa agaaacaaat tcgaatcgtc
    53581 cgtgcatatt ttctcctccg gcaaatagat ttggcgtcgg aatacccatg taagagattt
    53641 ttgaaccatc tgttcctcca cgaactggtt cgatcactgg agagatacca agctcgatca
    53701 ttgcttgttt cgctaattcc acgatgctca tatctttttc aatgatttct ttcatgttgt
    53761 aatattgatc atacatatct actttgattc gttcttgatc aaatcgctga ttcaactctt
    53821 cttggatatg tgtgatttgt gctttgcgtg cttcgaattt ttcacgatca tgatcgcgaa
    53881 tgatataact catagaagct tcttcaggat tcccatccaa tgccatcaaa tggaagaaac
    53941 cttcgtatcc ttccgttttt tctggaactt catcggctgg aagctgatta tgaaaatcga
    54001 ttgctaactg tagagcattg atcattgtat cttttgccgt ccctggatgt acatttttcc
    54061 cttggatcgt aatatttgct tgagcagcac taaacgtttc atactgcaac tcacctaaag
    54121 gaccaccatc gactgtataa gcaaaatcta catcgaattg ctcaacatcg aatttatccg
    54181 ctccgacacc gatttcttca tcaggaccaa aagccacttt gatggtaccg tgagggatag
    54241 aaggattatt gatcaagatc tccattgcag tcatgatttc cgcaatccct gatttgtcat
    54301 ctgctcccag taatgtactg ccatctgttg tgatcaatgt gtggccttca taatttttca
    54361 aatttggaaa atcttttgta ttcaatgtat agcgttcttc cgcatctagt acgatcgtag
    54421 actcgccatc atagttttca atgatttgtg gattgactcc tactgcatta aaatctgctg
    54481 tatccatgtg ggaaataaat ccaatggaac gcacttcatg atcaacattg cttggtaatg
    54541 ttcccataac gaatccgtta tcttcattat agaaaacatc agctaagcct aactcttcta
    54601 attctttttt caattcttgc gcaaaagcaa cttgtgtctg agtcgatgga gtcgttttgc
    54661 ttgttgcatc ggagcgtgtt tctgttttga catatcgtaa aaaacgtggc aaaagatttt
    54721 cgtacatagt attctctcct tttaattaaa ttgaaatggg tttgtatttg tttcagaaac
    54781 gaaaaagtta atatcccaat tttcttcttg tttccaagat tcaaatttct cgataaatcg
    54841 ttgcttgcat aacgattcaa tataatgacc gggatcaatt gcaatcaacc cagcgctttg
    54901 catatcatga gccgtatgat aatagatatc tcccgtgata tagacatctg ctctttgggc
    54961 gattgcttgc ggataaaatt tttcaccgct tccaccgcaa atcgcaatgc gcttcacaga
    55021 ggattttgca ttttttggct ggactattct cagtccatct agttggaacg cttcttttac
    55081 ttgttctaca aatgcctcta tagaaatttc ttgcggcaat tcacctactc gtcctaaccc
    55141 aaacatttcg actggttcat ctatagcgaa aagatcataa gcaggttcct cataaggatg
    55201 agctgaccgc atggcttgaa tcacttgttt ttcgatagtt tccggcaaaa taacctcaac
    55261 ttttgcctct tgaacttgtt ctgtcttccc tactttccca atcgctggtt gtgcaccagc
    55321 ttccggagta aatcgaccgt gtccaatcga ggtaaaactt gtaccggtat aatcaccttg
    55381 tgtaccagca ccagctgcag ctaatacttc acgcattttc tgtgcatgat ccacaggtac
    55441 ataaacggcc agttttttat aatgaatctc atgagtcttt actaaataac tctccacttc
    55501 aataccgaga agttcacaaa accagtcatt cagtccatcc caaataatat ccatgttcgt
    55561 gtgtgctgca tagacggcaa tatcatgttt caacaaatct gcatacattt tttcttgtgg
    55621 ctgatcagta accagccgtt ttacaggacg aaagattgga ggatgtttag caatcagcaa
    55681 atcgattttt ttcttgattg cttcttcgac cacttctgga cgaacgtcta atgtcatcat
    55741 tactcgttgg attggcttat ccaatgttcc gatatgcagt ccgactgggt ctccttcttc
    55801 agctagccac tgaggacaat agctttcaaa cttttggatg aaagtgcgtc cgctgattgt
    55861 catggcttta aaacctcctc aatcatttgg atttcctgct cgatttgttt ttgacgtgcc
    55921 tcttgattag ctgcttgttt gagctgttca cggatagctt ttctttgttg aagctctctt
    55981 gtccattttg atttgaagat ctcacttttc tcttcaagca gaaatggccc gaacatcagc
    56041 tccatttcat tgtaagtaac tggtttttgt tctttttcgg ctacaatgat ttcatatatt
    56101 tttttatttt cttcaagtat tttttctgat tggattttat actgattttc ttgcagccaa
    56161 gatcgtaatg tacgctctcc gatgtttggc tgaaggatca aacgttcttg tccgcttaag
    56221 cgttgattca acttgccagc ttctaggata tctcggatca gtgaacctcc catacccgca
    56281 atcgtgacag ctgtaatacc atcttgtggc tggatagcat ctagaccatt tgcaaggcgt
    56341 acggtgatac ggtcttctaa tccatctttt ttgacttgct tacgtgctga ttcataagga
    56401 ccttgaacga cttcaccagc aactgcatat tcgatttttc ctcttaatat caatgcaacg
    56461 ggtaagtaag cgtgatctga tccaatgtct gctaaacgag cggattcagg gacaaagtca
    56521 cccactgcgg ctaagcgctg agataaatct aaatggttca tagcttcact ccttctagat
    56581 aattatagca ttttccaaat aaaataagga gactaggaat aaaaaaattc ccatatctcc
    56641 ttaaaaaata taccttttcg ttctataaaa caacattttc ttatttttga aaaaatgtta
    56701 ttggttattt gttcaatgaa acatcaataa tcgaatctcc aggaacttgc ggtgggatag
    56761 acatcgtcat gatcggcatc tcaactaatg taaattggac tttgtcaccg attttcaatt
    56821 catttatgtc cacgcttatt ttttcagcag tagcatttaa gatcactccg tcattgctga
    56881 atgacgttcc catattcgct ggatcttctt tggccatgac atcgacgagt ttcaactgaa
    56941 gcgtttcttc ttctgcttct acttgagtaa tactttcaat cgttccgaca aatatgcttt
    57001 gtctctccgt tttcgtactg cttgttttta ctgtttgacc cgcatcaatc gaatcaacag
    57061 aacctgtgtt gctatctgcg ctaccgcagc ctgctaaaag aaaaaataga ccaactacag
    57121 atatactaga aaaaatagcc ctcataaaaa atcctccgtt taagtttctg cattacttgt
    57181 tgcggtgatt gtctccggtc atttctgtcc atataatgat tcgctgacct gcttttacta
    57241 ctaggtcaaa tgtcagttgg acttgtcaac tgttcaacca ttgcgtcggt tgcgaccagt
    57301 catttcgatt tcttttgtca aataacgtat gcgttccatt atccgtttcg cttttagcgg
    57361 ctcttcatct ccacgttgag tgacggacaa atgctgttcc aattcatcca ttgtaaaatt
    57421 cgatgagaag aaggttggta actgttcctg catccgatat tgaaggataa caccgaatac
    57481 ttcgtctcgt atccaactac tcatcgcatc tgcaccaatg tcatcgatca tcaaaatagg
    57541 tgaacgtttc actgcatcta acttttctgc cacttgatct tttccgattg cctgtttcat
    57601 ctcaacggca aatgtcggaa aatggactag cgtcgtggtg aatccagcaa tcgctaattc
    57661 tctcgctgtt gctcctaata aatatgtttt tccaatacca aaacttccta ctagatacag
    57721 tcctttatga tacccttttg gatcagcagt atatttctct acaaaatcta gggcttctaa
    57781 gctcgcatat cctcgtccat ctgtacgttc aaagttttca aaagaagccg attgaatatc
    57841 ttttggcata tccattgctt ttactcggct tctgatttct tcttgtcttt gccgtgctaa
    57901 caatgcttcc gttggtacat aagtgacatc cacataatga aaattcaacg tcagcttcgg
    57961 ctcatagccg ggagcgatca tcgttggatc gtttttttga tatttacgct tttcttgcac
    58021 gaattcatac aatttagcgt aacttttttc aatatccgct tgtgtcaatt cttcttggtg
    58081 tgcgcttaga aaagcttgaa catccgcatc atttaagact tcagcgatca tttcagcata
    58141 cttttcttga taattgcgtt tgctgatgat cctcttcaat tctttgccta cgtcttccac
    58201 tagatatcac cctccttttt tgccaggtat tctttaaaac ggcggtcaat ctctgctttt
    58261 ttctcgctgc tgatctgttt ttcatctttt ggctggttga cccaatcagg aagcttttcc
    58321 cgtcgaacat ttcgcttgcc agtttgataa tttgtttgct tcttttgttt tgattgtttt
    58381 gcttgattac ttatttgccg aatgtgctgg atcgcttctt ctgctgtggc gattttcttt
    58441 tgtgcccatt catttgccac tgtatttaca taactggcat ttaagctagc attattcttg
    58501 atcactagta cataattcag caaaacattg atcacgctac tggaaagacc tgattgagaa
    58561 acaagatctt gcagtaacca gttttcttgt ttagaaacat atccgccttt ttctgacttg
    58621 attgcttcca gatatttcat cggtggaatg ctctgtgctt cttttatcag ctgaagcgct
    58681 gcgtttgtca aatgttcgtt tgacgagggt tcattactgt tttcagaaac cgcaactgtt
    58741 tcttttgttt gcttcaccgg acgtctctgc attgccaaaa tggctttttg cagttctttt
    58801 tcagatactt tttgttcact aaagtcataa gattgactga tcagttcgcc aagtgtcaat
    58861 tcatcgaaac cgtaaagctg atgatacatg tcgacttgtt tgatgattgg atcatcaaga
    58921 cttgcaatat gtttttttgc cagccaatca ttcaaaaact gccaatcgaa tgtcgaatct
    58981 gcttcaagta atgctactga ttcagattct tcaaaagatt tattcagcga ttcgatgttt
    59041 tcttgattag cagcgtacac tgcttcattg aagcgataaa catctaaaaa tttttttgtg
    59101 attttttgat atccctctgc tgtatgcctt ttaggttcaa agaattgggt aagcttctgg
    59161 aatcgtcgtt caccaacttt ttccagaaga agaaaagcca gaacagagtc tttgaaaaat
    59221 gctttaggaa tgagtggttc taacagctca taaataaaac gaggtcccag atcactatct
    59281 tctttaaaat aaacatccag taagccgatt ccttctagct tttttcttgc atcataaaat
    59341 tgcgggatac cgcagcctag actactaagc agatctgcat gcatcccttc aggacctttg
    59401 ccagattctt gagagatttc tgataacagg gtgaaataga tactcaaggc ttctccgccg
    59461 attagtggct gataaagata cagcaaggcg ttcttgctgt cttctctcag cggagccgct
    59521 tttcttcctt ggtaaatatt ttttggttga agctctttcc aagcattttc caaggaaatg
    59581 cctccttttt gtttcttaat tgttttcttt attattctct ttattatttt cttttgcttt
    59641 atccacgata tcttgcaact cttttaagaa aacagacata tctttgaact ggcgataaac
    59701 acttgcaaaa cgaatataag cgatttcgtc taaatcaact aaatcttcca tcacatattc
    59761 accaattaga ttcgtcgata cttcgttttc tccgagactg cgtacgcggt tttcgacatg
    59821 gttgacgatt tgttccattt gttccatagc tacaggtctt ttttctgctg aacggatgag
    59881 tcctcttaaa attttatcgc gattgaactc ttcgcgttcc ccgtttttct tgattactaa
    59941 taacggagca gcttcaattc gttcaaatgt agtgaatcgg aacgaacaat tctcacattc
    60001 gcgacggcga cggatcgcac gtccatcatc tgcttgacgg ctgtcgatta ctcgtgaatt
    60061 attatgttga catctgggac atctcatttt gtctcacctc ttgcatcgca ttttatataa
    60121 aggatgtgtc tttctttaca actagttgta ttataacacg aaacaaatca caaacgcgac
    60181 tgtcctaccc aaaaaacacg gatataagaa caattttttc tactttcatg cgtaattgtg
    60241 tcccctgtcc ttactaaatt tcaattttcc aatactgatc accttgatta ctgagaaata
    60301 acttacacaa aagctgattt agtcatctag cacaaaaaac ttgaagcaga tgaacacctt
    60361 ctcatctgct tcaagtcaca tctcgatttt ttactatttt ataacttctc ttcgattcct
    60421 gtatagtgtt tcattcgctg ttcctcgatt ttttgctcat cggaaatgtg gtcactttct
    60481 gggagcggtg ttttactacg atcaggtgtc ggattttttc gttcttgagt caaatcttgc
    60541 cgcttcgctt cttcttctgc ctgctggtct tctatttcat cgattcttgc ttggtactgc
    60601 ttttcttttt cttctgctgt ttctgattgc gtacgacctt catcgattag attttcttta
    60661 ttgagcatct cgccgatttt ttcttttgcg ttacctacga ctttatcctt ttgatttttt
    60721 aatgatccca tcgctatccc tcactttcta tatactcagg atagcaaaat tgacacagat
    60781 actcaaagaa agcgattagc aaaaagccaa ttttcgattt gtcccacaag tttttctttt
    60841 gttccattgt tgtcgaacaa aatatccgca cgctgctttt tttcttcgat tggaagttga
    60901 ctactaattc tctgctgcgc ttgttctagc gtcagttgat tacgtttcat caaacgctga
    60961 agctgagttt ctggcgtagt ataaacgaca gctactgcat ccatatagtg gtcataatga
    61021 ccttcgtaga gcaatgggat atctacaatt actaaaggat gattggaact tagagaggcg
    61081 atttgatctt ttatcgcttt tcggataaac ggatctaata gctgatcaag tttttgccgt
    61141 ttttcctttg atggaaaaac aatcatccca agtttccctc gatctagttg cccatcaggc
    61201 tgcaatacct cttggccaaa cactgataca attttcctca gagcaagcgt tccaggctca
    61261 acagtttctc tggcaatcac atcgccatcg atcaaaggaa atccatgaga ctgaaagact
    61321 ttggctgccg tacttttacc ggtagctatt ccacccgtca aacctaaaac aaatcctact
    61381 ttgcgatttt tagcctttga caattcggac aatagtgcgt ccccctttgt gccacttttg
    61441 ttttcacgat cggcgttcca caacgtatac atggtttgcc agtttgctga tagacatgca
    61501 gtgctacttg aaatccgcct gattctccta atgcattcaa ataactgcga atcgtggtac
    61561 ctccggcttc tattgcacga tccaaaacat caatgatcga tagacgtaat tgttctacct
    61621 ctttggggcg cagtgtgttc gccggttgtt ctggatggat cttcgcttcc cataatgctt
    61681 catctacata aatattacct agaccagtca ctagacgttg gtctagcagc aatggcttga
    61741 ttgctttgtg ggactttttc agtccatttg cgaaatctgc taataagaag ctatctggca
    61801 aaggctcagg tcccaatttc atgattcctc ggtaagttgc acttgctcct ttttcgacga
    61861 ttgtcatacg accaaatttt cgtacatcgt tgtagcgaag ttggcttcca tcctcaaaaa
    61921 agaaaagtac atgcgtatgt ttatcgattg gtgtattttc tttcgtaaat tgatattttc
    61981 cttccattcg caagtgtgag atcagttcac aatgatcgag atgaaaaatt aaaaacttcc
    62041 ctctacgtcc aatggattgg atggtttcgc caacaagaga agcctcaaag atgggtgtct
    62101 ctggttgctc gatgatcttg ggccacaaga cctgaacttt ttgaatcgtt tttcctacta
    62161 ctaaccgttc caatccttta cgaacggttt ctacttctgg taattctggc attttttctt
    62221 ttcaccttca ttatattgct ctgtcttaaa caatgtttat tttgcttcgt accacgtttt
    62281 tccccaactg ctgtcagtga tcagtggtac atgaagagaa acagcttgtt ccataacttc
    62341 cttcaccaat ttatctaatg attcaagttc tttttccggt acctcgaaga caagttcatc
    62401 atgaacttgt aacagcatcg tagcttgaag acctgtttct tttaatcgtt tatccaattc
    62461 gatcatcgcg attttcaaaa tatcagcagc acttccttgg attggtgtat tgatagctgt
    62521 tcgttccgca aaagaacgga tattgtaatt tcttgaattg atgtctggca gatatcgacg
    62581 gcggtgatac agcgtttcga cgtagccttg gtcttttgct tcgcgtacga ttctttccat
    62641 atattctttg acacctgggt atttttcaaa gtacgtatcg atgtattgct gtgctgcttt
    62701 tcggctgatt cctagatttt gtgaaagtcc gtaatcagag atgccataca cgataccaaa
    62761 attcactgct tttgcctgcc tacgcatatt tggtgtgaca tcctctgcct tttcgattcc
    62821 aaatacacgc atcgctgtgc tggcatggat atcttgacct tctaggaagg cagctttcaa
    62881 atgttcatca tttgagatat gcgcaagtac gcgtaactcg atttgtgaat agtcagaaga
    62941 ataaatcagc cagtcttttt ctctaggaac aaatgcctga cgtatctttc tcccttcatc
    63001 taatcgaatc gggatgttct gcaaattagg atcaacagag cttaatcgtc ctgtttgggt
    63061 caatgtctgg acataacggg tatgcacttt tccatctgat tggatcactt tcagcagtcc
    63121 ctcgacatag gtagattgaa tttttgcaat ttgacgatag gtgaggatat cctctacgat
    63181 tggtgcttgt tcacgaagct gttccagtac atctacggct gtggaatatc cagtttttgt
    63241 ttttttgata acgggtaatc ccattttttc aaataagatc actcctaatt gctttggtga
    63301 attcaaattg aattcttcgc cggcttcttc gtagattttt tgttcgatct ctcttaagcg
    63361 agcagagaac tcgcccttca tttcttgtaa gcgagtcgca tctactttga tcccgcttat
    63421 ttccatctct gccaaaatga tagacaatgg cagttccatt ttccggaaaa gatcttcttg
    63481 gtttttatct gccagttctt ggctcaattt tggtgtcaac gcattgattg cagctacttt
    63541 tcgcgctaaa tgagcaaaaa agagttcctc ttcttctggt aaaccttttt tcgccccttt
    63601 gccgtataca gcttcatctg attggatatc gttgtatccg taatgagcag ctattccttc
    63661 gatatctgtg cttttttcat tcgtatcgag aaggtatgca cctagcaaga catcaaaatc
    63721 gattcctttc gtttttccag tatagcggtt taaagcaaca taagttcgtt tcgcatcata
    63781 tacttttttc agccgagtcg gatcagtgat ccaagaatgg aacgctcggt tttcgaatac
    63841 agatagatcg ttcgtgacat aaattttctt ttctgtcccc cacgctactc cgacgatttc
    63901 ctctgtatga taattgtcgc ccatcatttc cacgtacaac gccatatccg tagtaaacat
    63961 ttcctctttg aattcatgaa cgacttcaaa caaaatatca tccattttta cttcttcttc
    64021 tacgatattc aatttagaaa ggaactgatt gaaatccatt tctttataaa acggaacgag
    64081 tttatcgaga tttttccctt catacttcaa tgagtcgata gagacatcca caggcgctga
    64141 agtattgatg gtcgccaatt ttttcgataa gaaagcctgc tctttgtcat ttatcagatt
    64201 ttctttcatt ttgctttgct tcatttcatc gatatgttca taaattcctt cgactgagcc
    64261 atattgtttc aatagcttga tagctgtttt ttcaccgatt ttagtcacac cggggatatt
    64321 gtcagaggca tctccggcta gtcccttcat gtcaataatc tgttttggcg tcaacccatc
    64381 atatttttcc gctacatgtt ctggtgtata gctttcgata tcgctgacac cttttacagt
    64441 gatatccact tttacttctt tactagctaa ttgagtcaaa tcccgatcac ctgaaagcac
    64501 gacgacatca aattgatctt tgtctacttt ttctgccaaa gtaccgataa tatcatctgc
    64561 ttcataattg ggcaattcgt aatactgtac ccctagtcct gtcaacaaat cacgtatata
    64621 tggcatttgt tctttgaatt cgccaggtgt tttggatctt ccacctttgt actccgcata
    64681 catttctgtc cgaaaagtcg tttttcctgc atcgaacgca accagaacat gagtcggttg
    64741 ctctttttgc ataacatttt caaacatcgt attgaatgca tagattgcat ttgtatgaag
    64801 accgtttcta tttttgaaac gttcaagaga attgtgaagc gcaaagaatg cgcgaaaagc
    64861 cacactgttc ccatcaacga gtaataattt attttttgtc atcttcttaa ctccttactg
    64921 taaagttctt attcattcta acaaagaatc ctgcggaatg cgaaaagaaa aagcgggacc
    64981 ataccaaata attcggtata gccccaactg atgaattttt ttctttttta gttgttccgt
    65041 ccaaagattc tcagaaacgc caagaacaag ttgataaagt ccaaatacag cttcaatgcc
    65101 atgaatacag caattccact atgtgctgtt ccgtttgtct ggacatagat attacggatg
    65161 ctttggttat cataagctgt aatccctgca aagatgacga ctaacagtag ggagatgaac
    65221 agctcaacta cgctacttct caaaatgaag atgttcaaga ctagtgcaat gatcactccg
    65281 attaaagctg cctgtcctgc tcttccaacc ccgctaagat ctctttttgt tgttactccg
    65341 acaacagaca tccccatgaa catcaaagta gctgtcaaga aagcttgcgt tactgttcca
    65401 atatcgtagt atgcaagagt aaccgctaat gttatgccat tcaaaagaga gtaggcaata
    65461 aatccaccga ttgctaagct cggattcttt tgtgctttta cgcctagaac cattactaaa
    65521 atcagttcaa cgatccacag acccacaaag cctagtggaa aattattgat aaaagttgct
    65581 aattgcaaag gaaataccca aagagccaag taagaagtga ctgcactaag ggcaagtccc
    65641 atacctaaaa atccataaac ttttgcataa aaacgattga tacctgacat tgatgtactt
    65701 ggattattca ttcaattcac cttcactttc gattgctatt tccaattcag gaacttgtgg
    65761 cggttggacc ataacgacag catccaacac acgatcttcg ttcgtattct ccgcttctac
    65821 agaaatcgtc accacatcct tcatcttatc tacttttatg acctcaaact gaaaagtcag
    65881 tgtttcataa tggaaaaccg gttcaataaa attgacagaa aaattgacaa catgtgatcc
    65941 tggtccagga agatgctttg aaattgcact tgtgatgatc cccatcagca tcactgatgg
    66001 aacgattggc tgttgatatt ctgttttttg tgcaaagtca tgttggatat acaaaggatt
    66061 tgcatcattc gtcaatccca aatacagcaa aagctggtta tcttcaatag attctgttaa
    66121 ggataacgag tcgccttcct cgatttcatt tattgttttt cctagttttc tcggcttacc
    66181 tatgttcaag atagaaaccc tccagtttat ttttaatcat acattattgt accaaaagta
    66241 gcgtaaaagg caagttctgc tcccttgatt taacagattc ctatagttta cagaggtcgt
    66301 gaaaaagctg tcctgcatca aataataaga acagccaaga aaaaacagct tctcatgttt
    66361 ttgatttgat tgggcttatt accgcagatg caagcttttg aacaccgttt atcataagtt
    66421 gcaaaaaagg gggcttggca agatttttgc cactccccct ctttctattt ttataaggac
    66481 actgcagtaa ttgtattaca gtacattttt cgtcgtgctg cttaaaagtt tttcatacgc
    66541 ttgttcaaat ttttgaacat ctccagcacc catgaagatt actactgcat catgataatc
    66601 taacaatgga gatacattat tttctttgat gacttctcca ccttttttga ttttcgctcc
    66661 aaggtcttca atcttaacgt ttccttgttc ttcccgagcc gaaccaaaaa tatcgcataa
    66721 gtaaacttta tcagctaaat caagtgcttc tgcaaattca tccatcaatg caatcgtacg
    66781 cgtaaacgta tggggttgga aaactgcaat tatttcttta tctggatatt tttggcgtgc
    66841 gccatcaatc gttgctttga tctctgcagg gtgatgcgca taatcatcga ctacggtcat
    66901 gtctgctacg atcttttcac tgaatcgacg ttttactcct gggaaagtca gcatttcttc
    66961 tgcaacttct ttcagatcca gtttttcgaa ataagctact gcaataacac ctaaagcatt
    67021 taagatattg tgtttaccga atgctggtac agtgaagtgc ccaacaaatt catccccatg
    67081 atagacatca aaagcagaac cagaagttgt gcgttcgatg tttcgtgctt ggatatcatc
    67141 gttttctgtg acaccataat aataaatcgg cacatttgct tttaatttgc gtaaataagc
    67201 atcgtcacca tacgcaaaaa tagctttttt cacttgtcca gccattgttt ggaaagctgt
    67261 aaatacatcg tcgatacttg tataataatc cggatgatca aaatcgatat tggtcatgat
    67321 tgcatagtct ggtgaatagg caaggaaatg acggcgatat tcacaggcct caaatgaaaa
    67381 gaattccgct tgcggatcac catgtcctgt tccatctcca attagataac ttgttggacg
    67441 gacaccactc aatacatgag agagcagtcc agtcgtactt gtttttccgt gagagcctgt
    67501 tacagcgata ctcgtataat tttggataaa atgaccaata aagtcgtgat agcgaatcac
    67561 ttccaaacct aattcttttg ctcgctggat ttcttcatgt gaatcaggaa atgcatttcc
    67621 tgcaatgatc gtcatccctg gttttacatt atctgcgtta aatggcagaa tcgtgatatt
    67681 tgctttttct aaatctcttt gtgtaaagaa atatttttca atgtctgatc cttggacatt
    67741 tagaccttgt tcatgtaaaa caagagccaa ggagctcatt cctgaacctt tgataccaac
    67801 aaaatgatac aatttatttt gattttccat ttgaatcctc ttctcttatc tagcgtccat
    67861 tcttttagct attacattca acacgctcct cattatctta taaacgattg aaaatttcaa
    67921 ccaaatttat ttggaaagga ggattcgctt gctaaaatgg tcaagtacga gaaaaatccg
    67981 tttttattga ctctttaatt ctggtgtaag aagaccaaac ttcctctgat atatcaatgt
    68041 gaggaataaa atcttttcct ttcggaccat agccgttctc atcgtcatgg agacgttcca
    68101 tttctcctaa tactagcgca tggaaatatt ccttaggcca ttgatgattc agttcttttg
    68161 ctgtaaagat gatctcttca gaaaagtgaa ggatttccgg cacaaatggc acagcattcg
    68221 cgaaaatagt ttgttcattt tgccatactt tctcaaaagt tgctcgagtc ctgcgttgca
    68281 gtgtcggatc attcatcaat aagatttttt ctggtacagc tcctaaggaa tgaagaatct
    68341 ccagtgaaaa agtggcgttc tctccagaat ttgtagactt cgattctatc agaaaagcct
    68401 tatcgggcaa atcatagact tcttttagat actgacgaca gatttcactt tcactcatgc
    68461 catcttcaaa atgaaatcct tgcttttcaa aattctcata aaggattcta gtcgcatgcc
    68521 ccacccctcc gaccaaaaac aattgatcta cttggccatt taaatacatt tgtgctgctt
    68581 tatcagctaa gataggaaga cagtttccag ctaaaataag tgtaggtgcc gtcagttcct
    68641 caaaatttcc ctcttcaggt gcggctaaaa aatttaatag ctgattccag tcttttagat
    68701 tcctctgctc acttttttcc aaaggccttc tatcctttca tctgattttt tgtgcttcat
    68761 taaagtcttc tctttttgtc tcaatccatt tgatttctcc atgacatctt ccacaacgat
    68821 atttgcgtac atcgattctt ctcttgcggc agatcgtggc agaacaatct tggcatcgat
    68881 aatactccat ctttatctgt ttcttcgtca aggctggtgc atagcgcaac cctcctgttt
    68941 ttttcaaaag atacttgaaa tccatatctt tatgctgata ccctcttcca gctagatgaa
    69001 gatgataatg gcaaagttca tgtttgatga ttcctgcaat cgtctcttcg tctgactctt
    69061 caaatagctt cgcattaaaa tctaaatgat gatcgtttaa atgatagcgc ccgccagttg
    69121 tacgtaagcg tggattgaac attgcttggt gcttgaaagg aagctggaag ctttttaatg
    69181 atatctcttc tactaactgc tgcagttctt cttgtgtcaa tttttgttac tcctcattgt
    69241 tactcttcat aaggggaaag catcgtcaaa ctgattctgc cttttttcgt atcgacttgt
    69301 tctatccaaa ctgttacgat atctcctact gacacgacat ctgtaggatg cttgacgaat
    69361 tttttgctga gtttcgatat atggacaagt ccgtcttgct tcacaccgat atcaacaaat
    69421 gcgccgaagt caatgacatt acggaccgtt ccagtcaatt ccatccctgg tttcaagtct
    69481 tccatactca atacatctgt acgtaataag ggcgctggca tctcatcacg catatctcgt
    69541 ccaggttgtg tcagcccagc taaaatatcg gctaacgttt cttctccgac tgataggctt
    69601 tcagccagtt tctctacgga taatcgtgtc aatttttcta ctgcttcttc tgtaccaagc
    69661 tctttttctg aaagttggac tgaagttaat atttcttttg caatagaata actttcggga
    69721 tggatacctg tgttgtccaa aatgtttttc ccaccaggga ctcgcaagaa tccgattgct
    69781 tgttcatatg cttttggtcc taagcgtggc acttttttca attgagttcg tgcggtgaat
    69841 tctccgtttt cttcacgata aatgacaatg ttttgggcag ttgttttatt caatcctgat
    69901 atatgctgca agagctgcgg gcttgctgta ttcacatcca cacctacttg gttaaccgct
    69961 gtttccacaa caaaatccaa ttgttcagcc aaacgttttt gagaaacgtc atgttggtac
    70021 tggcctactc cgacagcttt aggatcgatt ttgactaatt cagctaaagg atcttgcagg
    70081 cgacgggcaa tagaaacagc acttctttct tcaacttgta gatgcggaaa ttcttttcgt
    70141 gcaatttcgc tagcggagta aacagaagcg cctgcttcgt tgacgatagc gtaataggtt
    70201 ttatggtcgg cggatttcaa ctgctcagcc acaaaaagtt cagattcccg actggctgta
    70261 ccatttccga tagctaccat atctacttga tatttattaa ttaattggat aaaagctggt
    70321 ccagcagctt ctctttttgc ttgcgctgca ggtttatgag gataaataac ttcgattgct
    70381 aaaactttcc ctgtcgcatc tacgactgct agtttacatc cagtacgata agccggatca
    70441 aatcccagga caactttacc ttttagtggc ggttgcaaca aaagattacg gaggttttcg
    70501 ccgaaaatag cgattgcttg ctcatctgcc ttttcagtca attcattgcg cagttctcgc
    70561 tcgattgctg gctgaataaa gcgtttataa ctatcctgat aggcttctct gacgaatgaa
    70621 gaagaaggag aggcaggatt tttgactatt tggcgatcca agtaagctaa aattgctgct
    70681 tcatctactt gaaagaatac tttcagaata tcttcttttt ctccacgatt agtagctaat
    70741 attcgatgag aaaccatttt atggacgggt tctgcaaagt cataatacat ttcatatacg
    70801 cctttttcat ctgcttgctc atccttgaca ttgctgacat acataccttt gttatacgta
    70861 taagaccgaa tccaagtccg aaattttgca ttatcgctga cttgttcagc aataatctca
    70921 tgagcaccgt gcaacgcttc ttcggcagaa gagacttctt tttctttgtc aatatatttt
    70981 tctgcttcag attgcacctc tccatctgta agctgcatca gccacttcgc gagtggttca
    71041 agtccttttt ctttagcaat cgttgctttt gtccgtcgtt tttgtttgta tggacgatac
    71101 aaatcttcca cttgttgcat tttcacggct tgggtgattt ctgcttctaa ctcgggagtc
    71161 agtttccctt gttcatcgat tagccgaatc acttcagttt tacgtttttc taagttttca
    71221 agataggcat accgctcttc gatttcacga atctggactt catcaagact tccagtcatt
    71281 tcttttcggt aacgcgcgat aaaaggaaca gtgtttcctt catttaacaa attaagtaca
    71341 gtagtcaact gcttaggacg atagtctgaa agttcttttt gtacaagctg aatgatcgtc
    71401 tggttcaaat tttccgtcat taaaatgcct cttttctgct aaaaattgct tctttattct
    71461 atcatacttt ttatcctggg ttaaactact gaaagaaaca atattctcta taaaaataaa
    71521 aagagccgca acaaagtcac agctccttca ttctttccat tagtcagatt ccatgccaag
    71581 gtccttcgtt gttctgatat tcaatatctt gaagaatacc ttccttgtca aaaacaaccc
    71641 catgcaatga ccctccgaat acagccccac cgtccattcc gattttatga tcctgaatcc
    71701 agaggtctgt tgtctgcata tctccatgga gcattggtgt aatcgtatgt ccaaatacaa
    71761 ttgtcttacc tgtattgttt ttcccttcat gaaatggttc ccttatccaa ataaagtctc
    71821 ttagacttgt cttacgccag tctttctttg tcaaatccac accggcatgg acaaaaagat
    71881 aattttccca ttcataatac aaggggcgct ggactaaaaa tttaatcagt tctgaatatc
    71941 tcgattggat catcatcgag atttcagttg gggagtattc ctccgatgcc cctgggtgaa
    72001 tcaggctttc aaacgtttct tttccaccat ttctcatata aggcgcatac cagtcctccg
    72061 gtgattgcag aaattgcaaa aaatattctt catggtttcc ccggaggtaa atggctcctg
    72121 tttcttcgac taattgcttt cctaataaaa aacattcttt tgtacgagga cctcgatcat
    72181 tgagatcccc taataaaaca agctgatgga tctttggatc ataatagtga ataagttttt
    72241 caaaaagctc atgtttgcca tggacatccc caatagcata aatcaatgat ttcatgtgga
    72301 tcaccatcct caacgctagt atagcgcata ttggaaatgg tcgacaatca aaactattgt
    72361 tttctattta attaaagctg taaaccgcag ttctgcttct tctggagaga ttccatggtc
    72421 ttgaacatag cgattgcgcg gatgtttcgc acactctatg ctacatgctc ctaaatgttt
    72481 ttcttcattt tcaatggaag caagaatctg acgattgcac tcaggattgc tacaattgat
    72541 atatcgttca catggtgttc cgtcaaacca gtcgcgaccg acgatttgtt tatctacttg
    72601 gttgatatcg acagcgatcc gttcatcaaa cacatacatc ttgccgtccc ataattctcc
    72661 ttggacttca ggatccttac cataagtagc aataccgcca tgcagctgtc cgacatcttt
    72721 gaatccttca cggacaagcc aaccagaaaa cttctcgcaa cgaatgccac cagtacagta
    72781 ggtcactacc cgtttttcca taaattcttc tttgtgctcg cggatccagt ctggaagctc
    72841 tcgaaaactg cgtatatctg ggcgtacagc ccctcgaaaa tgtcccaagt catattcata
    72901 atcattccgt gcatcaatca ccactgtctg ttcatctaaa atagcttctt taaattcttg
    72961 cggtgaaaga taggcacctg tcacttggtt tggatcaatg tcctcttcta gctttaaact
    73021 tacaagctct ggacggtatc ttacaaacat cttcttaaag gcatgtcctt cgcttggatc
    73081 gatcttgaac atcgtatcag caaatcgagg atcagctttc attgctttca tataggcagt
    73141 cgtgttttca acggttccag acacagtacc atttattcct tcttcagcta ctagaatacg
    73201 acctttaaga tccaaagatt tgcaaaaggc taaatgattt ttggcaaatt cctctggttc
    73261 ttcgattttt gtataattgt aataaagcag tacttgataa tccatgtatt tcttccttcc
    73321 ttcttttcgt tcctaaacag tataaagaag gcgttcgcat ttgacgattt atttgcttgt
    73381 gtataattac gcatggaaag ttttttgttt acataatatt attatttgaa ttaaaaagac
    73441 ttcgctttcc tgtttcgcac agaaaaa
//
LOCUS       DAFBVQ010000009        59527 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.009, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000009 DAFBVQ010000000
VERSION     DAFBVQ010000009.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 59527)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 59527)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..59527
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.009"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(341..1651)
                     /locus_tag="LLC22_000744"
     CDS             complement(341..1651)
                     /locus_tag="LLC22_000744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBK5434041.1"
                     /translation="MRTKKGIINALNFKTNDTQQDDTIILQKAIDQGAKEHLPVFIPK
                     GIYLVGALFLKDKSHLIFEEGAVLKGRTDIEAFPEIDTRVAGVEMKWPAAILNVLSAK
                     DILIEGKGIIDGQGDHWWELYWGKDQKSGTRAEYDQKGLRWIADYAIKRPRACLLYHA
                     EHVVVRDLIFQKSGFWNLQITYSNDVLVEKVIIRNNDGPSTDGIDIDSSTNVRVYECD
                     LACGDDCIAIKSGRDGNGARVNRKSSRIEVARCKIRSGYGVTIGSEVSAGVSDVYIHD
                     IDFFQSDCGIRMKSSKERGGVIENIRVENLNMIDVQFPFSWIMDWHNEYNRKNSNDLA
                     QMPESWQAVAEEIPESKQMTKVKDIHIKNVQACLSPGYSLPSRAFDLVAFPEKPIEDV
                     CFSHCQITAKEFGRIEAVQNLCFKSCDLSIETGNTAANNTFDNR"
     gene            complement(1663..3081)
                     /locus_tag="LLC22_000745"
     CDS             complement(1663..3081)
                     /locus_tag="LLC22_000745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5434042.1"
                     /translation="MLSQNAVTANTIKKEKKEFGISDKIGYMFGDLGNCFILGLVNSF
                     LMIYYTNVLGVSGAIVGTLFLISRILDAFADVMVGRLCDVSELTETGRFIPWIRKMKY
                     PFCLVTVILFLPFVQHLPMTVKIAYIFVSYIVYGIFLSTINIPYGAMAAAISSNPNDR
                     TSLSTFRSIGSAIGGSTTGFFIPILMYTHNKSGQQVVSGNHFFWISIGCAAIAFVAYM
                     LTCKLTTERVRVVKNEKVSASQLVKGLLANRALIILVIVDIFIVINQILAGTNMTYLF
                     NDYFHNKQAMSVALLFTYGTVVVLAPFATKLTKLFGKKEASVFALLASSCMYLLMYFL
                     HITNAWVYLILLFIATLGSGLFNLMVWAFITDVIDYHQYKTGLREDGTVYGVNSFARK
                     VGQACAGAVGGFMLALIGYQSSTTGGAIQSVLVQERIYTMANLLPAFCLFVSAIILLV
                     GYPLNRSKTVFIGEELKKINER"
     gene            complement(3321..4889)
                     /locus_tag="LLC22_000746"
     CDS             complement(3321..4889)
                     /locus_tag="LLC22_000746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBK5434043.1"
                     /translation="MQTIKVKNPILRGFNPDPNILRVKERYYIIVSSFEWLPGIRVYE
                     SKNLVNWSHTTDILTTQVSLQGNPTNGSIWAPQISYADGLFYLVYTDVKSAGRPFKDV
                     HNYLITASEITGPWSEPIYLNSNGFDPSLFHDLETGKKWLVNELWDYRLDTPNKSSGI
                     VLQEYDAEKKKLDGPIYKIFAGTELAKTEAPHLYFRNGYYYLMTAEGGTGRGHSVTVC
                     RAKNITGPYELDPGFPMLTASDKPASTLQCTGHGSLVQTPSGRWYMTYLCTRPLNGAA
                     ILGRETAIQEVYWTSDDWLRLKDSQTTPMEEIMIETNEEVQQEKDHQFMDTFEGELKK
                     NWNARRILPNADWCDTKCRPGFLRLISGESLQSTFEHHLLAIRQTDFTFDAETAFEYM
                     PNNFNQMAGLVLYLNESNYIYCYVTWNEDKGKCLRMIESENGVAQIEDWTIPLTEKKT
                     FLKVTVKKETAQFHLKDVSTEEWKKVGPQKNMCILSGGFTGNFIGIAVHDLNKKRGSY
                     ADFEFFKYDGKDHL"
     gene            complement(4893..5303)
                     /locus_tag="LLC22_000747"
     CDS             complement(4893..5303)
                     /locus_tag="LLC22_000747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4064 domain-containing protein"
                     /protein_id="HBK5434044.1"
                     /translation="MKRKWELLLGMVGGSLSLIFFGGLAVTLSNMSASEFKKSYQSLA
                     VDHSTLSLENTFGLLQDMTGLFAVVLFISLAFLAVALFLTAKGKYLTTATGLYFITGF
                     ILLIGTQFIAFPFAFFYFAAGAFSLYRVRMRKGA"
     gene            complement(5300..6223)
                     /locus_tag="LLC22_000748"
     CDS             complement(5300..6223)
                     /locus_tag="LLC22_000748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pectin esterase"
                     /protein_id="HBK5434045.1"
                     /translation="MRMKDKLIIGKNAIDTPTDFETIQEGIDYLAGLPDSHPKVLIVK
                     EGRYDEYIESRLSNFKLVGAGTVVISGNRFAKQEYLDGSQLGTFRSATFFLEGSNVVL
                     ENLHIENTAGPGEKVGQAVALFNSGDRVSLKNCRLSGYQDTLCTGPLPDLQKDGTPFC
                     TPASANPEYCRQTYEYCWIEGTVDFIFGGADAVFHQCHIHSLASKNPGYITAASTPKN
                     QKTGYRFESCTLTAEPDTRNVYLGRPWRPYANVLFEACKIGGHVHPTGWDNWDDKKNE
                     QTVKFSERNNNYETSIKRPEWIHLEKQGVQK"
     gene            complement(6220..7098)
                     /locus_tag="LLC22_000749"
     CDS             complement(6220..7098)
                     /locus_tag="LLC22_000749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl oligopeptidase family serine peptidase"
                     /protein_id="HBK5434046.1"
                     /translation="MQLNDFLGAPSSRHTPSGKRLYREKQNGFMLEYYQLYLNELETV
                     PALYAYPEKEGPFPPVLYLHSHGGDFSVGKSELIHGAPYLASPSFAEVLTGMGYAVWS
                     IDAWGFEERGGISESELFKQFLLTGKTLWGMRIYDVISLIDYLETREDTDTQRLATIG
                     LSMGGLLSWWVTALDSRVKVCIDLAAQVDIEILLLHRRLDHHGFYYYVPNLLTAYTTL
                     AIQEKIAPRPRLSLVGKNDTMCLDEGVLKLRKGLDKKYQSMGSPENFSSFSLTGGHME
                     TQEMRNIWKQFIREHL"
     gene            complement(7085..8422)
                     /locus_tag="LLC22_000750"
     CDS             complement(7085..8422)
                     /locus_tag="LLC22_000750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324619.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 28 protein"
                     /protein_id="HBK5434047.1"
                     /translation="MYDILTFGASIDELNTEAIQQAIDAAASDGGGTVVVPAGEFLTG
                     ALFLKSNVELHLSAGAVLKFSDDPKDYPVVHSRWEGVHRKVYASCIYAQNVENISVTG
                     FGTLDGNGKKWWHTFRNEPDNLAYPRPKLMSFHNCHRITVKDIKLIQSPSWTINPILC
                     SNATFDNLTILNPADSPNTDGIDPESCKNVRISNCHIDVGDDCIAIKAGTEDTYERIA
                     CENITITNCTMVHGHGGVVLGSEMSGSIRNITISNCIFQETDRGIRLKSRRGRGGIVE
                     DIRVSNIVMDNVMCPFILNLYYFCGPRGKEPYVWEKKAYPIDERTPAFRRIHFSNITA
                     RNVHASAGFIYGLAEQFIQEITFDNIDVSMAQDAVPGVPAMMTGIEEMSRQGFYIGFA
                     GKVSFNQMSIENHEGPAFLLENTKEISIEKFQSNQSENMDELVVRKNFAYAVE"
     gene            complement(8425..9528)
                     /locus_tag="LLC22_000751"
     CDS             complement(8425..9528)
                     /locus_tag="LLC22_000751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 88 protein"
                     /protein_id="HBK5434048.1"
                     /translation="MENWSKKLAKSIMERTPRLYEEKWYKGKWSYDYGVVLKGFQLLW
                     ERTQEKIYFDFIKDNIDYFVQEDGTIRGYSVEEYNIDHVNTGKLFFLLYKETGEEKYK
                     KAAELLSQQLANHPRTSEGAFWHKEIYPYQIWLDGLYMGSPFYAEFIQNFSEEKDYQD
                     VLRQFEISYKHLFDPKTNLLIHAWDEKKVQPWADPKTGLSHHFWSRSIGWYLMAAADT
                     YELLHEETDCSLLKEILEKTLAALLPYQEENSGTWYQVTTETKRKGNYLEASGSSMFV
                     YAMAKGIRLGLLNKEEWLPQVKKSHQGLLDEFVLETKEGWLNLNKNCQVAGLGGADQR
                     DGSYAYYISEPIICNDQKGVGAFLQALIEVEAL"
     gene            complement(9602..11110)
                     /locus_tag="LLC22_000752"
     CDS             complement(9602..11110)
                     /locus_tag="LLC22_000752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5434049.1"
                     /translation="MKKATLVKLGLSFAGILALAACGSSSSNSSSETEDGKAKITWLN
                     ILHHASPPTDTIVNLIEEKTDTELTFNWIPDASKEERLTTALASDELGDIVTLQIAML
                     KNSSVRNALKSGVFWDVSEYLKDYKNLSQISEDRIEAASIDGALYGVPIQKDYARAGL
                     VIRKDWLDNLGLDVPTTMDELYEVAKQFTENDPDGNGVDDTVGFGDRAPSDIRYTSFK
                     LFTSYFGAPNGWAVDDNGKFTPEFDTEEYMKALNFSRDLFENGYLAQDFAVTQKTDQQ
                     EQFAQGRTGIYTGMVDIKNLKTMGQGIQDDMELVPVNKISDGEGGGYHVWSEGNGIGG
                     LLAFPKSQVKDEAQLKKLLQFVDDLLEEDVYKLMTGGIEGTHYELNDDGSIEFIDMDL
                     WQQEVQPLSSSRPSEVTFSFKDTDPEKEFSNQLIKENEEFAVMDPSVPLDSPTNNEVG
                     SEIEKIVIDATVQYIMGQLDEDGFKKAVEDWKAQGGDRITQEYEEAYKAAAQ"
     gene            complement(11076..11768)
                     /locus_tag="LLC22_000753"
     CDS             complement(11076..11768)
                     /locus_tag="LLC22_000753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBK5434050.1"
                     /translation="MLQSLDKINGRLNRILQLVYLNFLWGGLVIAGLGVFTFGPASYA
                     MVAVIRKWLRSKETFPLTKTYFTYFKENYRETLLMSWIYGAIGIVLLVDLSFIHNWYL
                     RIALYIAAFIYVLSALYIFPIMAHYDWKGYFFKMKMAFLFGFSHLHYSLVLILSMVGI
                     YLMIIQTMPGVLTFIGGSLFFSAVTWTANSIFCHLEWKNSYTEKTEENKNIIKTVKEK
                     IYEKSNARKIRS"
     gene            complement(11790..12764)
                     /locus_tag="LLC22_000754"
     CDS             complement(11790..12764)
                     /locus_tag="LLC22_000754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5434051.1"
                     /translation="MESVKKQEPFQLTLSKKEEKLRRRKKIIAGIKTNKFLYVMILPG
                     VLYFLIFRYLPMGGLVIAFQDYQPFLGIMGSPWVGFKHFIRLFTEPTFFTLLRNTLIL
                     FGLNIFVFFPMPIILSLLLNEVTNKRLKNGIQTIIYIPHFMSWVIIVSITYVFLNVDG
                     GVLNEFLATMGFEKISFLTSPEWTRTVYIGQVIWKELGWSTIIYLSAITAVDTQLYEA
                     AEMDGAGRLRKTWHVTLPAIRPVIITLLILKIGQTLDLGFEHMYLLLNSLNRSVAEIF
                     DTYIYTAGLKNGQLSFSTAMGLFKGVVGLFMVILANKIAKKLGEDGVY"
     gene            13064..13936
                     /locus_tag="LLC22_000755"
     CDS             13064..13936
                     /locus_tag="LLC22_000755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5434052.1"
                     /translation="MKKKVSIGERSFTLFNNTFLILLALICIVPFLNIIATSFASTQE
                     VVAKKFILFPTTFSLDAYRYILSTPTIFRALAVSIGVTGVGTIVSMCATSLMAYGLSR
                     KYLFGRGFVNFLVVFSMLFSGGMIPTFLVVRSLGLVNSYWAMILPVAVNAMNMIIMRN
                     FFQALPDSLEESAKMDGCTDFGVFFKIMLPLALPSIATISLFYAVTYWNTYMTAILYI
                     NDSSKWPIQILLRQIVIVSSGMQAESSAVDVIPPAQTVKMAVIVIATVPMLIVYPFVQ
                     KYFVKGALVGSVKG"
     gene            complement(14394..16592)
                     /locus_tag="LLC22_000756"
     CDS             complement(14394..16592)
                     /locus_tag="LLC22_000756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434053.1"
                     /translation="MKKSTVFYKIFLPMFLLGAVLVIGFSLFIYQNTYESIESSYLTD
                     KKNLLRQVKTNVEWKIRTIEYSFSTYGSTKNFSDIFKHPLTYTDYSTYSEIRKELNFI
                     ETIVMDDNNYDLVSLAGKWGVINGSLSQLTEEEIEKYQQKYINNKNNLFWQKKNKGIE
                     MVISLPMFEKEKYALGIATIEKHTIEQVVGESGEDILSIENEVGNLFTTQTVKNKEQP
                     TVLTDVDLDYNQLKVIREKDKTYIVLKSDYNNWIYRLEVDSSAIGAMIRNLRIGLVAV
                     SLTLVGLIGLLSYLFSDRFARPISQIQERLNLKSKGFSGKELDLVAQSVSRIIGEKEA
                     LSAHLVTQKPQLETLFVLSLFRNRVERRELDQRLQQFGYSSQNDCYYTALVQIDLLED
                     SHGGERDLLLLAINNMITEIVPKENRMLPIVLNEEMQATIYRMDKDDAEASKKVMEYC
                     RLIQKRVKEYLNLTISIGISNRFETLNESKQSVDRAKEALYYRVNTGPSSIIFYQEIV
                     PAAHEKTLIRYPIEEQNRLFEAIRSGNQEVKNLVHELIDALFAQNKNPLSREVVSVRL
                     INELVQLGQLLGVDSKNFDNMKQIYVKALNNYHPKELEKLVLEQLVLPITECSQAITD
                     HEFKNLSENIMHIVYTEYDRDLSLDVIADRLHYNPNYLSNVFKKETGEKFGDFVQNHR
                     LEVAKKWLKETNLSVKEIAERLQYRNPQNFIRFFKKKESITPGEYRKKYL"
     gene            16824..17816
                     /locus_tag="LLC22_000757"
     CDS             16824..17816
                     /locus_tag="LLC22_000757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434054.1"
                     /translation="MVTIKDVAKAAGVSHTTVSRALNNSSLIKNETKQKIRQLAKEMN
                     YSPNYSAKGLVNQKKYLIGLFFSSLHKGTSSNFLADSIAGIHSVLDTNYSLSVESIDV
                     VDLTEINLQRYDGLIVMSQSDDDQPFIDYLKEKEFPFVVVNRHINDPAVINVTADDAA
                     GVMQAVDYGIGCGHTKIAYIGGKKNFRSTKEREKGVLKSLKKASIPVNPAYFLTGDYS
                     LESGLQNMEYLLSLSDLPTLVFCGNDDIAIGALRAVHLAGLRVPQNISLIGFDDSPVV
                     SYLNPPLTTVRKPLKEMCQEGTKLLLDLIEGRTIEQSKIELSTLLILRESINYL"
     gene            17876..19297
                     /locus_tag="LLC22_000758"
     CDS             17876..19297
                     /locus_tag="LLC22_000758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagaturonate reductase"
                     /protein_id="HBK5434055.1"
                     /translation="MKKLTKELVKKNEAPVKVLQFGEGNFMRGFIDWQIQQLNNQQLF
                     KGNVAIIQPLEQGLGNMMNQQDNLYTVILQGLSNGEIVDTSEIITVVEQMINPYDEWD
                     AYLSLAENDDLAYIVSNTTEAGIQFVETDNLTDTPPQSLPGKLTAFLYRRFKLNKAGF
                     TIIPCELIDRNGERLKEIILRYAEKWDLEPAFVEWLEKENVFCCSLVDRIVPGYPRED
                     AGVFNQRHNYEDQLMVKAEPFMLWVIEGPKELENQLPFKQAGLNVIITDDMTPYRERK
                     VHLLNGPHTAMVPLALLAELETVEEVMKDPLFSAYVDQLFNLELIPMLSLPKDELAIY
                     ADQIKERFLNPFAHHKLEAISLNSVSKFSTRLLPVFKKYIEEQNQVPPLITVSLAALL
                     LMYRGDQVKPHDDEKTISEFTDAWSDNGTAIPRLLQNAALWGEDLSQIPNVTDTVQEI
                     AAKIDQKGVRSVLQEMKGTMVHA"
     gene            19290..20789
                     /locus_tag="LLC22_000759"
     CDS             19290..20789
                     /locus_tag="LLC22_000759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="altronate dehydratase"
                     /protein_id="HBK5434056.1"
                     /translation="MLETLQPTMKLNRRDSVVVALTPIPKQTQLTIDQQTITTLEDIP
                     QGHKIALGDLKAGDNVIKYGYPIGHVTTDVTAGQWLHTHNVKTNLSGELDYRYEKDVH
                     PSHYLFENRTFQGYLRKNGKVGIRNDLFLVPTVGCVNGIAELIVKQFKEKHPDLGQFD
                     HITILKHPYGCSQLGKDHQNTREILADAVNHPNAGGVLVFGLGCENNTVPEFKKILGE
                     YDEERVKFLVAQDVYDEIEQGVALLEELLTAAENDQRISVPLSKLNVGLKCGGSDGLS
                     GITANPLLGAFSDYLIAQGGSTILTEVPEMFGAEQVLMARAENEEVFDSIVDLINDFK
                     QYFLSYGEPVYENPSPGNKAGGITTLEDKSLGCTQKSGSSPVVDVLQYGEKIRKPGLS
                     LLQAPGNDLVAASALASSDCQLVLFTTGRGTPFGSYVPTVKVSTNTTLFERKGHWMDF
                     NAGVLLEQPMEVILESFVQKIIAVASGEETKNEQNDVREIAIFKNGVTL"
     gene            20828..22222
                     /gene="uxaC"
                     /locus_tag="LLC22_000760"
     CDS             20828..22222
                     /gene="uxaC"
                     /locus_tag="LLC22_000760"
                     /EC_number="5.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628919.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucuronate isomerase"
                     /protein_id="HBK5434057.1"
                     /translation="MFLSDDFLLKDDWAKKLYHSYAKNMPIIDYHCHLDPKEIYENNN
                     FSNLTEAWLGGDHYKWRLMRACGVPEEKITGNASDFEKFLAWCQTVPKIIGNPLYSWS
                     HLELKRFFGIDLLINEENAEKIWTQANEILAAPDFRRREIAKKSNVEVICTTDDPADD
                     LHYHQLLAHEEPDLKVLPSFRPDKALNIEKEGFNAWVTLLEEAADQTITTYQELIEVL
                     GQRIEYFHQHGCRVSDHALDILRYKEADETVLEEIFQKARANKLLSSDEIDAYRTETL
                     IHLTHFYHSHNWTMQLHIHAYRNCNTQMLEKLGPDTGYDGMNDLSLTIPLQKLLNRAE
                     ETDQLPKTILYSLNPNDYPAILALMGCFQKEQNGKLQLGSGWWYNDTRAGMRDQLTQF
                     ADGSALGNFVGMLTDSRSFLSYTRHEYFRRVLCEFLGEMVMRGEAPEDEQLLGSLVQA
                     ISYTNAKNYFGFFA"
     gene            22381..23064
                     /locus_tag="LLC22_000761"
     CDS             22381..23064
                     /locus_tag="LLC22_000761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnogalacturonan acetylesterase"
                     /protein_id="HBK5434058.1"
                     /translation="MPTIHIAGDSTAAEKDENKRPETGWGEKISAYFSPEIQINNQAK
                     NGRSTKSFIQEGRLARLASQFQPNDFLFVQFGHNDQKIQEERGTLPFGSYLKNLQIFF
                     ECAKKANVQMVLLTSVTRRDYLENGTLNPDILGDYPKAMRAFAEKHHIPLLDVFSRSQ
                     ELFQTFSKEETKKFYLHLIPDTCKNYPEGLKDNTHFSPEGADKVARIIVELIKESRLP
                     LANYLQKGV"
     gene            23066..23902
                     /locus_tag="LLC22_000762"
     CDS             23066..23902
                     /locus_tag="LLC22_000762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344933.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBK5434059.1"
                     /translation="MFPLNLGIRAHDLDVRNREEIVQKVSQLHLSHIQFAPQKAFPEQ
                     LKLTDMTLGSAAYFGEYFQKNNIELSILGCYINLSSKNQEVRAQALATFKQQIALCSA
                     YQAKMIATETGSVSVGYTKENFTEEAYQIARNSIIELVAHAENFGVTVAVEAGINHPI
                     YNYQLAKRLIDEVASPNLKIILDCANLMHKENHADQEKVIRGALDNLHGYITALHLKD
                     YIMENGKIRMVPVGKGCLDFRPVLHYIKYERPLMYATLEATPEIYVPEAIEHLQFIYQ
                     DC"
     gene            23913..25667
                     /locus_tag="LLC22_000763"
     CDS             23913..25667
                     /locus_tag="LLC22_000763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434060.1"
                     /translation="MEERIQKSYQKYHANAFQTLLHLYQGNYWRFAMSGLFFIIKHLP
                     SWLMPIAIANVINAASSKDSSQLQAIYFNAFLMACLIGQNILTNYFHVKYHSTSIRQV
                     EAGLRATLIKKIQELSIPYQKELQSGRIQSKIIRDVEAIQTLSSQVFVSGLNIAVNLF
                     VALGITLYKSPVVFMFFLLTVPLAAFVTLFFRKRIRQSNSDFRQEMEETSAKVIEVIE
                     LAPIARAHGLEKHETTRLNKHFTQIYEKGFHLDILQSVFGSVSWASFQIFQLICLIFT
                     GILALQGRIQPGDVVMYQTYFTTIVNSVSGMITLIPTISKGMESITSIGELLIAGDVE
                     TYHGKKKIQHLDGNFRFEDVSFLYPDSLKPIIDHFSLEVKAGETIAFVGPSGSGKSTL
                     LNLLIGFIQPTSGKIFLDDQPLDELDMRSVRNYLAVVPQTTLLFSASIKENITYGLKN
                     VSKERLDEVIEAAQLSSLIDQLPDGLDTLVGEHGNKLSGGQKQRISIARALIRQPKII
                     LLDEATSALDNQSEKKIQQALNYLTETPTTFIVAHRLSTIKEADKIVVIDEGKIVEIG
                     TYEKLLAQKGYFYRLKNE"
     gene            complement(25943..26284)
                     /locus_tag="LLC22_000764"
     CDS             complement(25943..26284)
                     /locus_tag="LLC22_000764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBK5434061.1"
                     /translation="MSNIYDSANQIEREIRELPEFKALKEAYEKVQANEEAHKLFKDF
                     QAMQIELQEKQMSGQEFSDEDAMKAQEMAVKIQSEEVINDLMQKEQGFSTIINDLNRI
                     IMTPVRDLYSE"
     gene            complement(26352..28523)
                     /locus_tag="LLC22_000765"
     CDS             complement(26352..28523)
                     /locus_tag="LLC22_000765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PBP1A family penicillin-binding protein"
                     /protein_id="HBK5434062.1"
                     /translation="MDFQSILEKIKAALISFWRWIRPYLGQFHRWRKRIWKKYHVNKL
                     ILLIGLICVLVTSIYLFILAKQANVETLKSGLSQSTVIYDKKNEEAGTLYAQKGTYVE
                     LNAISPYIQDAVISTEDRNFYEHHGFDIKGIARAAVRMVLSGGTSGGGGSTITQQLAK
                     NAYLTLDQTFDRKAKELFLAIEIEKKYSKEEILTMYLNNAYFGNGVWGVQDASRKYFG
                     VDATNVTLSEAATLAGMLKGPGIYNPIDHPKNANDRKNTVLSVMEENGKITKEQEQAE
                     SQTDISAYLNDTYDNSDSGYRYPYYFDAVIDEAVNEYGLDEEDVMNKGYKIYTALDQD
                     YQKQLEATYQNSALFPANASDGAMVQSASVALDPNTGGVQALVGRRGDHVFRGFSFAT
                     QMRRSPGSTIKPLSVYTPALEAGYKPSSILKDEPQSYYDAHNFDGTYQGEVPMYQAVA
                     QSLNLPTVWLLHEIGLQKGYDKAEEFGLPLAKSDKYYGLALGGLEKGVSPLIMAGAYS
                     AFANDGQMYTPHLITKIVDSTGAVIVDNTNKKPKQVISKETADEMTSMLLGTFSNGTA
                     AAANPAGYTIAGKTGATETNFDATKANDQWMIGYTPDVVISTWMGYEESSKLHYLEGT
                     SGNVVGKVFKSAAEGILPYTSKTGFSVADAYATGGQVVAADQVGNTGNSNGESGNWQD
                     NLNQYGEQAKEGLKNFGDMVKEGVQGIGEAAKDLWRKYQGE"
     gene            28692..29591
                     /locus_tag="LLC22_000766"
     CDS             28692..29591
                     /locus_tag="LLC22_000766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK5434063.1"
                     /translation="MVQLVCDCTERSTLVKITITLPMNHPETTIRDLLEKEWLVPRKV
                     RHFLRIRKNVWINQQPALFHHEVKGNDQITLLFEETDYNYQEVQLGDAKHIRVLYEDE
                     HLIIVDKPAGMKTHPNEPTENSTLLNHLAAYLDTKQQRPYVVHRLDKETSGAVLFAKN
                     PFVLPILGRMLEQKMIYRRYQAIVWGEIAKDMTITNKIGRDRHDRRKRVVDDKNGQSA
                     LTHVTVNKVLSEQTQVYCVLETGRTHQIRVHLAHKGHPIVGDPLYQNRTAERLMLHAL
                     ELHMIHPFTQEKIVGKALPGLWE"
     gene            complement(29662..30519)
                     /locus_tag="LLC22_000767"
     CDS             complement(29662..30519)
                     /locus_tag="LLC22_000767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5434064.1"
                     /translation="MYGGIEAGGTKFVCAVSDGGEILEKLSIPTTTPEETLDQVFEFF
                     DRYELKGIGIGSFGPIGIDKTKDNYGYVLATPKKGWAQFDFLGTIKERYNIPAAWTTD
                     VNAAAYGELKQGAAQGKNSCIYLTVGTGIGAGVVINEEIFSGIAHPEMGHIWVKRHPD
                     DHYEGTCPYHKDCLEGLAAGPSIEARTGIKGQDLPQDHPVWAIQAYYIAQALINYTLT
                     LAPEKIILGGGVMNQDHLLQKIRQQFVELMGGYMETPQVSEYIVRWGLPNESGIIGSL
                     LLAEHEHQK"
     gene            complement(30504..33206)
                     /locus_tag="LLC22_000768"
     CDS             complement(30504..33206)
                     /locus_tag="LLC22_000768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-mannosidase"
                     /protein_id="HBK5434065.1"
                     /translation="MKKKVYIISHSHWDREWYMAYEQHHMRLIELIDDLLELFEVDPS
                     FNSFHLDGQTIILDDYLQVRPEKRQAIQQAINEGKLRIGPFYILQDDFLISSESNVRN
                     MLIGMEESRKWGTPVMLGYFPDTFGNMGQTPQLMKQAGISAAAFGRGVKPIGFDNQVL
                     EAENYSSQYSEMWWKGPDQTAIFGLLFANWYSNGNEIPVEKEAALAFWKQKLADAEQY
                     ASTNHLLMMNGVDHQPVQKDISKAIHLANELFPDYEFIHSNFTDYLEAVQKDVPEDLG
                     SVEGELTSQETDGWYTLANTASARVYLKQWNTKVQRQLENITEPLATMAYEVSGNYPH
                     DQLDYAWKTLMQNHPHDSICGCSVDSVHREMIPRFEKADEVGKYLAQDSLEQLTAAID
                     TTGFPKDSFPFVIVNTAGMDKTGEAEITIELERKRFAEGIPEQLYQELENLPKRKYHV
                     ETKSGATIPAILSEETVQFGYDLPKDRFRVPYMARMIKVTLPLENMPAFSWETFALVE
                     GEAKAEEKETMIHQSGRIIENGPLHLTIEKNGTITMEDRKNKRKLNNLHIFEDIGDIG
                     NEYIFKQPFCDQPILSSNKENSEVKVLVDTPEIAKISILQEMEIPVSADERLEKEQQM
                     VVEFRYRKAERSKEKRILQIKTIMTIRKDSKKIDFETTLDNQMKDHRLRVLFPTKLHV
                     EHHEADSIFEVVKRPNHVSKSWENPTNPQHQQAFVNIHDEEYGVTVGNFGLNEYEVTE
                     DGQIAVTLLRSVGELGDWGYFPTPEAQCLGEHRFNYSIELHGPEEKFSTYLHAYAAQI
                     PFSTQQIKHHEGTLISKQQYLTIKSETFAITALKRSKFSDKVVVRGFNMSSHLEKLEI
                     TKDNGKTVILNLLEEPTKQAVVPIIQPYEIRTIGFEEENECMAE"
     gene            complement(33219..34508)
                     /locus_tag="LLC22_000769"
     CDS             complement(33219..34508)
                     /locus_tag="LLC22_000769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 125 protein"
                     /protein_id="HBK5434066.1"
                     /translation="MAYKDIPKSVQKFMEDITQKCGDIHADWAKNFTAAFANTLLTTV
                     KKQNDGTTFLLTGDIPAMWLRDSTAQVRPYLVIAKEDEELADMISGLVKKQFFYINID
                     PYANAFNEEANGAGHQTDHTKMNDWIWERKYEIDSLCYPIQLAYLLYKNTGKTDQFNQ
                     SFIEGIKKILDVFKTEQDHEHSPYTFVRDTTRKEDTLINDGRGAKTAFTGMTWSGFRP
                     SDDTCRYGYLVPSNMFAVVVLGYVEEIFQTILDDKEIVQQTQKLKKEIQEGIQNHGRT
                     VNQKGQTIYAYEVDGMGNATVMDDSNVPNLIAAPYLGYCSEQEEDYLQTRRTLLSKEN
                     PYFYEGKYAKGIGSSHTPEKYVWPIALAMEGMTTSDKSEKERILNLLVATDAGTHLMH
                     EGFDVNNPENYTREWFSWANMMFCELVMDYFDIRVEK"
     gene            34658..35704
                     /locus_tag="LLC22_000770"
     CDS             34658..35704
                     /locus_tag="LLC22_000770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434067.1"
                     /translation="MNQPLYQTIFNDLQTAILTGELPVDSQLPTEKELSRTYKVSRIT
                     SKRALTELEQLGLIYRVRGKGSFVKSASPEQILASPTKTRRILFLLPYVADLSVGDFS
                     KGLNPVMQDKQIDVMMTTLDFLQNKTAKELINEFDGLIYYALDTEQHLDLLFELSLKE
                     FPVVILDKKIYELPFPTVLSDNFQGGALAASYLIEQGHSKIAYLFGTQTHPQSVRQRY
                     LGYLEALDKAGLTFHTSLDDKSATLDELLSYITKYEVTAFVCENDVVAIQTMNLLRQH
                     GYHIPEDFSIIGFDDIQAAALVDPPLTTIAQDFEQLGKLAGDALVTWLETKDRPSDSK
                     FPVSFIKRQSTKEK"
     gene            35706..37859
                     /locus_tag="LLC22_000771"
     CDS             35706..37859
                     /locus_tag="LLC22_000771"
                     /EC_number="3.2.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GH92 family glycosyl hydrolase"
                     /protein_id="HBK5434068.1"
                     /translation="MNIGQIDTRHATANQPNFSNGNCQPYTGVPFGMNYFAPQTTDQN
                     GSWWFHPDDRVFQGYRLTHQPSPWMGDFSHMLFTPINGKLQENTLFHAQSSYRPEESI
                     FCPTHLSICQLRYGICSTLIPSMYGGILSIDYSKNDSGLLLSFPGRHQLFVIDPYTVE
                     GKITHFAGSEDPDFSFYFILRFEYPLTIDELAVSNKNSDSIPLYFEQTKKQTIRFGTS
                     FISSEQAAYNLELEQNQSKETYLAHSQEQWQSYFDRIQLTHHDQQQLRTFYHNLYRVF
                     LFPQTFYEIDPSGQKIHYDTTSRSIKPGVLYTNNGFWDTYKTVYPLYSLIAVEKYEEM
                     LEGFLNSYRESGYLPKWLSPDERGLMPGTLIDAVIADAAVKDIRRDLMPEFLTAMEKG
                     ATVQSKHPNYGRQGTEDYLTYGYVPNHYHESVNHTLDYAYSDFCISQVAKVLEEEEMT
                     KKYQQQSLNYQNIFDYESGFMRSKDKDGKFREPFSANRWGQDYAEGSAWQSSFAVYHD
                     FSGLIGKYGGSERYKEKLIELCNQPPTFDPGGYGFEIHEMSEMAAIEFGQLAISNQPS
                     FHYPYLFSYIGQPEMAQPLLKQLMTQTFDDSPMGYPGDEDNGSMAAWYIFNSLGFYPV
                     TPGTGEYVIGMPLIDKAVLLLSNGKELTIEATPNRPQQQFIHKIKRMDKEYTKLYFTH
                     QDLLKGGTISYQLGIIPHPKKYQAKDLPFSLSNYN"
     gene            complement(38332..39783)
                     /locus_tag="LLC22_000772"
     CDS             complement(38332..39783)
                     /locus_tag="LLC22_000772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628234.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5434069.1"
                     /translation="MSVYQVLLVDDEYMILNGLKKIIDWQSLGFQIVATAENAKEGLA
                     VLEQRQIDLVVTDVTMPEINGLEFIEAAQKERHNFEFMILSGYQEFDYLKGGMQLGAV
                     NYLMKPVNKFELVESLKKIKTRLDQQNEQKNQQEIYQELLFSQWLNEELDEISEEEII
                     GQISEKQHRIVLIQLARTHDTLINRWLQERQQIFYYQRNYGDRVLITLLLEADEVDGF
                     CCFVQENFPDQEWLISIGEETDSLDKIPETFQQAKDNLQLHQFYGDKDEHVFYAVQAE
                     TKDQTIDFSSFRRVLQNKQLEVAQKMITDFFEQFQLAAMMPEDIRYSSFLLFMEIQRE
                     LIDLEDEEYLQGIEKIHQAKTVQELQQLLLSFIKKHQRQKKYSDNVEKVIVILHQHYQ
                     EPLTLKEVSENLHLNVMYLGQLFKKETKKSFSAYLNHLRMEKAKQLLLHSNQNINEIA
                     SEIGYNNTTYFSKLFKKIVGRSPKEYRENSGES"
     gene            complement(39780..41504)
                     /locus_tag="LLC22_000773"
     CDS             complement(39780..41504)
                     /locus_tag="LLC22_000773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5434070.1"
                     /translation="MNKFRILFSKGTLLNRLLRKYAVIMIGVTMTATVIFSIHTWEQN
                     QKQAENMTSDAVQSTSRMLNDKTTLSRIIKNQLVGNSEKIENVTTYLTKPIDQYLMYV
                     YEQQNSTDELVSFPNQIKDLYANYEELSAIYIVLNQLPEYYESSRENKGGEIKKGTPK
                     LLDAFYIKLPITQGGAESGSIFIGFQKKELDMILENLTSFNGLSLYMISGTTNRLYTF
                     HDNKIAKETFERQEMIITESLKKNSQLPIDDLEKNNFVQHQELSDDYRILAVLDKKSV
                     KIETGKNLAPLIIGIIILDNILLIFLYKTFKRYSQQVSIVMQAMDQTAAGNLETRIDI
                     TNTEYELKELSIGINEMLDSINQFVEDIYKLEIKQQDAHMRALQAQINPHFLYNTLEY
                     IRMYAISEGSEELADVVYAFSALLRNNTNQEKTITLKEELDFCEKYVYLYQMRYPNRV
                     AYHFMIDPDLEKIEVPKFVIQPLVENYFKHGIDFTRFDNALSVKVLQEGKRVRIIIKD
                     NGKGMTEKRLKQIEEKLSHPKVELHGSIGLQNVNERLRASFGSSYYMSLENNETGGLT
                     VSITFKEG"
     gene            complement(41497..42111)
                     /locus_tag="LLC22_000774"
     CDS             complement(41497..42111)
                     /locus_tag="LLC22_000774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF624 domain-containing protein"
                     /protein_id="HBK5434071.1"
                     /translation="MLGKVLEELFIRIWVIIKLTLYFWIYTFAGGIIFGLGAAWKTVN
                     ELFYLYGFEYKEITIKRGWNIYKRNFLRGNLLFSLFLSGTALLSYNLYLSVQIKGLIF
                     LAIDFILLFALLCLFATYQYSMILDSEYTISVPNLLKLSFISVFSSFSSFLKIIIGSG
                     IILGVTWQFKGLILFGVIGLLTVWNGTMTTHWREELDKQLESYE"
     gene            complement(42456..43913)
                     /locus_tag="LLC22_000775"
     CDS             complement(42456..43913)
                     /locus_tag="LLC22_000775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5434072.1"
                     /translation="MKLWKKLAFTGVSALLLGTLAACGGSGSKDQAEASNSDTLQMYQ
                     IGDKPDNFDQLMEVANKRIEKEIGVKVNINYIGWGDYEKKMNVIISSGENYDIAFANN
                     YVSNAQKGAFADLTELAPKYAEKAYNDLDEAYIKGNLVNGKLYAFPVNGNVFAQQVLT
                     FNKALLDKYDLSIDGIQSYADAEKVLKEFHEKEPNTAAFAIGQGFKVQGNFDYPLGNT
                     LPFAIDLDGDDSKIINQYDNETYIGLLRTMHSWYKQGLIPSDAATSNKDYPLEGNTWL
                     MRGETQGPYDYGDTILTNAAKQELVSKAITVPLKSTAQAQMANFVVSNTSKNKEKSVE
                     LLGLLNSDPELLNGLVWGIEGEAWEKVDGSDDKIKLLDGYQPNTHMSAWNTGNNKILY
                     TQESITDDMIAKRDQSIADAETSPILGFSFNTDSVKTELSNISNVMNQYLDGLNTGTV
                     DPDETLPKLKDALDKAGYDKVLKEMQKQYDEFRQE"
     gene            complement(43954..44874)
                     /locus_tag="LLC22_000776"
     CDS             complement(43954..44874)
                     /locus_tag="LLC22_000776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5434073.1"
                     /translation="MKKKKVERVQVRSFNKTANFFSNIMIALFAISCILPFIFVIAIS
                     FTDESILSTHGYSFWPEKFSIFGYTYLFDQMQDKIFQALFVTVLVTVLGTLINSTATS
                     LYAYAISRSNFPFRRFFTVFCLITMLFSPGMVANYLVMTNLLQLKDTIWALILPMAVS
                     PFNIIVMRTFFKRSVSDSIIESARIDGASELRIFVQIVLPLAVPGIATISLFAALGYW
                     NDWFNALLYIQDDKLVPLQYLLMKIQSNIQYLTQNSGAGSQLTGGLASVPGESARMAI
                     VVISTLPIAISYPFFQKHFVKGLTIGGVKE"
     gene            complement(44886..45833)
                     /locus_tag="LLC22_000777"
     CDS             complement(44886..45833)
                     /locus_tag="LLC22_000777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877947.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5434074.1"
                     /translation="MKKRKGFNHFFMNLWRYKALVLMAVPGMLWMIFFFYIPVMANVV
                     AFKNFHISADGFLASLRESPWVGWENFKFLFSSDQAFLITKNTILYNVAFILLNLLIS
                     VVFAIIMSELRNKRLVKVYQTMSLLPYFLSWVIISYFVYAFLSPDKGIFNQWITGHGG
                     EAVNWYNEPKYWPFILVFIGTWKGIGYNSIIYFASVMGIDPTYYEAAMVDGASKWQQI
                     KHVTIPQLIPLMTILTILAVGNIFRADFGLFYNIPRNSGALYDVTQVLDTYIYNGLTS
                     TGDFGMTAAAGLYQSVVGFVLLMITNTIARRFDSDSALF"
     gene            complement(46312..47031)
                     /locus_tag="LLC22_000778"
     CDS             complement(46312..47031)
                     /locus_tag="LLC22_000778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBK5434075.1"
                     /translation="MRLDKFLADMGLGSRKEVKGLIKKGTIEVNGQVVKSDKAQVNEF
                     EDAVTYLGEIITYQKDFYYILHKPAGVISATQDNHDQTVIDLLEDQDYREDLFPVGRL
                     DKDTEGLLILTNDGVFAHQLLSPKKHVEKEYLAEVSGIMTEEDIRLFAEGLIIDGDEQ
                     TLPAKLQIDQVDQETETSIIRLILHEGKFHQVKRMVKAVGKEVLYLKRIRMGKFWLPK
                     DLNKGQYRPMTKEELEQVREK"
     gene            complement(47080..48726)
                     /locus_tag="LLC22_000779"
     CDS             complement(47080..48726)
                     /locus_tag="LLC22_000779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5434076.1"
                     /translation="MDNQRKPALDQLTPQEKMARGSAWMTASNIISRLLGAVYIIPWY
                     AWMGENAKAANGLFNMGYNIYALFLLISTAGIPAAIAKQTARYNSLNEYGTSRRLFIR
                     ALQMMGGLGLLFALFMYIASPWLAHASGGGEELIPTMRSLSIAVLVFPCMSVIRGYLQ
                     GNQEMMPYALSQIVEQVARIFYMLLATFIIMKVMDGDYVTAVTQSTFAAFIGMLASIL
                     VLLYFLKKHQAYTSAFIHYSENKINIATKELLLDTVKEAIPFIIVGSGVTIFKLVDQF
                     TFMKIMSASTEYSNAQLLDLFSIFSANPDKLTMVVIALATSIASTGLPLITEAVTLKD
                     RVGLAKLTSGNLQLFSFFMFPATFGVMLLAYPLNTLFYTPDSLGSNVLIQASFVGLFL
                     GLYMLVSNMLQGMFENKAAINYLVIGFLVKLLLQYPAIRLFEVYGPLLATMIGFAVSC
                     TLILKRIHEVARFKPSFVWRRTLLIFILTLIMLLASWITKMIFGAFLNEDSKFQSLLL
                     ILVVAGIGALVYGYLALKIRLAERLLGPGIARLRHKLKIK"
     gene            48905..49495
                     /locus_tag="LLC22_000780"
     CDS             48905..49495
                     /locus_tag="LLC22_000780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319599.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5434077.1"
                     /translation="MTQEIKKLPVIFLGLFFITVGLNWFLLPHDIASAGVGAIGHLVE
                     TAFSIQRSVTVWSINLMMLLLAAVLLGKSVFFKTVAGSLLFPVVLEIVPKVEMISSHF
                     FSLISGSLLFSLGVYTLYTVGASNGGITIPPIIFHKFFRLPMPQGLLLTNSLIVFLNY
                     YVFGLLETLFVLLSITVSSLFMKILIRLSPVSRKFE"
     gene            49587..51092
                     /locus_tag="LLC22_000781"
     CDS             49587..51092
                     /locus_tag="LLC22_000781"
                     /EC_number="6.3.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-
                     lysine ligase"
                     /protein_id="HBK5434078.1"
                     /translation="MSFSLEDIRHLLLKENLLKEFVSTRGWHLDVPEKAEFLQLSYDS
                     RKADASTLFFCKGMNFKEEYLDSAIEQGIQYYVSEQPYENSAVGIIVTDIRKAMALLA
                     MAFYDYPQNKLKVIGFTGTKGKTTAAYFTKAILDHTTNKKTALLSTMNTTLDGKTYFK
                     SHLTTPESLDLYRMMSEAVENGMTHLVMEVSSQAYKTQRVYGLTLDVGIFLNISPDHI
                     SPIEHPTFDDYFYCKRQLILNSKTVVLNHESDYFDLLRETADLFQIPTITYGRSEESN
                     YQVIRSDKGTHGFTLSSHEDRLAICDTAYDILLAGGFNQENAASAIIAAALTGASSQD
                     AQDGLKEARVPGRMDQLIQSNGAHVYVDYAHNYLSLKTLLKFAKNEHPDGRVIVVLGS
                     PGNKAISRRHDFGKVLSETADIAFLTADDPAFEDPKKIAEEINEAITNPDLIVHYEMD
                     RPEAIRRALAESAPQDSVVIAGKGVDPYQKINGVDEPYEGDYAIVKRLIEE"
     gene            complement(51176..52528)
                     /gene="celB"
                     /locus_tag="LLC22_000782"
     CDS             complement(51176..52528)
                     /gene="celB"
                     /locus_tag="LLC22_000782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBK5434079.1"
                     /translation="MFDFLQKYLMGPMGKIAQLKIVRAVMAAGMASIPFTIVGSMFLV
                     LNILPLPFPFLEGFFNATFFKVSDLYMIVNTMTMGILSIYFAIVFAYELTSIERDEQK
                     LNVNPLTGALLSVFAFFMCIPELIMTDGKISLIASINETETVVNGIRMGSFVERLGTS
                     GIFTAIIMSIIAVELYCMCVKRNWVIKMPDVVPPGVSRSFTALIPTFVIAFVVMIING
                     LLVALGTDIFKMIAIPFGFVTQLTNTWLGVMVIYFLIHALWIVGIHGANIITSFLTPI
                     VLANMAANAQGANYPLAGEFNSSYVTVGGSGATLGLIIFIAFLAKSDQLKVLGKASLV
                     PGLFNINEPIIFGMPIVYNPYLAVPFFLAPMASATLAYFAIRLEIVKPMLAQMPWPSP
                     VGIGAFVGSGGDWKAAVLAVICAIIAFIIWFPFIKFYDNKLLNEEREKAAELASEKLK
                     "
     gene            complement(52528..53046)
                     /locus_tag="LLC22_000783"
     CDS             complement(52528..53046)
                     /locus_tag="LLC22_000783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434080.1"
                     /translation="MQDTVKRKIELEKKQLSLKNMYFNRYLIVRYLTAFFFFMNMQWM
                     ILLLSAKSLGSSLPMILILAILPAVGEQVKLYRKHQTNVPWTKWYFLFQSVFNLLVIP
                     VLFTSGFTFLYPFMANNNGGQLFVFILVVSGIFASAFIQYRLKKISLNQDQQYIRIKQ
                     YEKALYLGKENN"
     gene            complement(53062..53388)
                     /locus_tag="LLC22_000784"
     CDS             complement(53062..53388)
                     /locus_tag="LLC22_000784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIA"
                     /protein_id="HBK5434081.1"
                     /translation="MAEKINSETLQVTSFDIIFHSGNARTLIHEAFRSMRKEMFEEVE
                     EKLRQANEEILHAHQSQTQLLKEYASGTKIEMEIIMVHAQDHLMTTMTLLEVAQEMNY
                     LYQKNK"
     gene            complement(53401..55380)
                     /locus_tag="LLC22_000785"
     CDS             complement(53401..55380)
                     /locus_tag="LLC22_000785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5434082.1"
                     /translation="MKQKEKLLLRYLIDHKKEYVTSQRLASELLLSDRTIRNYLQRIK
                     ELVEKNGGKIIAKPGYGYQLHILQRLTFDLFLSRQEIVPGYAREPQGFYESEDRQKYI
                     LNQLLLEDAILFMDDLAEELYISRSSLTKDMQEIKERLIPYSLKIVSKHGQGTWIEGE
                     ERNRRHFIMDTFFGNHYGNSLKEYLGQSRFFPDISFEELVIIILDETREAKLKVSDFI
                     IQNLTLHLALGIKRLREGFEIKELGIEQEVSKRVEYQVAQRIVQRIEVIAGVSFPEEE
                     IAYLTLHLMAKSNHKENQNDQELSKELAKVLKRLSQEFHFSLVEDLQLFNGLLDHLSP
                     MMIRLSRGIRIENPLTEEIKKENPKVFDAVKRHFSNMPALKNYTINEDEWAYLALHLM
                     AALEKERAAHKLHALIICATGYGSAQLLKNRVVSEFGKNITVVSVKGYYEINETTLKG
                     IDLIISSIDLSTMFFKIPVLHVSIFLNEDDVRKIRKVVGESIPYHSSDRPIPAFSLQQ
                     KKQIYTEQLSEKFFKTYTYEPKKEEILHDLLQKLSINEEEGYIREMRKQIQQRENMGQ
                     IIFSDTVAVPHPAVPVGIETKVAVALIPSGMQWDQYQEIHFVFLVSPSYVENEGITVV
                     TKAIVRLVDQLKVQQEILAEPIFENFSSKFIKLIE"
     gene            complement(55401..55715)
                     /locus_tag="LLC22_000786"
     CDS             complement(55401..55715)
                     /locus_tag="LLC22_000786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736972.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIB"
                     /protein_id="HBK5434083.1"
                     /translation="MKKALIICAAGMSSSMMASKTTDFFKQKREEVLVDAVSATEGDN
                     MIKNSDFDLFLISPQTTMFLDKFKKLGESVGKPVVSIPFQAYVPIPTGIQKLAEVIEE
                     NI"
     gene            55883..56176
                     /locus_tag="LLC22_000787"
     CDS             55883..56176
                     /locus_tag="LLC22_000787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antibiotic biosynthesis monooxygenase"
                     /protein_id="HBK5434084.1"
                     /translation="MSITVNILYTSTNGQARKFAEEMVERNIVKAIRAEEGNEKYDYY
                     FPLEDPESLLLIDRWKDEEAIEKHHKSEMMAQINELRKKYKLKMKVERFTDLP"
     gene            complement(56254..57366)
                     /locus_tag="LLC22_000788"
     CDS             complement(56254..57366)
                     /locus_tag="LLC22_000788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5434085.1"
                     /translation="MTVKNKSKKKGRQQVDFYQSLQLDPFILKQKIREAASKKEKCMY
                     ICSLFLRSLFIVLFAICFIIIITTLFESKHKPYAVVLFCMLMSIRFVDFGYKISHSII
                     GLAIVMFSLLVAPYVQLIKWSVMGMLIHFILLSSILMATASDPKMGNASLYGFSYLFI
                     VYSLPKDSLNKNFFTQTSSLLFLFFCWFSVLLYRKHREKNKDKSLFKEIFLKGMYSQE
                     KIWMLIYAFGISLLIVAGEYVPFQRLMWAGFAFSSIVSSYGLMSIGFKERAVDRIIGS
                     LIGCVLFIGISQFIPFNWVGILGGLALGVCSTYRYKTVFNSFGALAITASLFGVPGAV
                     TIRIFENILGVCLGIMYIGVTEILIRKIREKHGLNH"
     gene            57519..57743
                     /locus_tag="LLC22_000789"
     CDS             57519..57743
                     /locus_tag="LLC22_000789"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434086.1"
                     /translation="MNGSIKKILRSIDKNLMITEVSYETLQKKKTLIVAAVLFPAPCV
                     CRNCGSAVVDGNRKLMVVKNKKKETIVHFE"
     gene            57753..57932
                     /locus_tag="LLC22_000790"
     CDS             57753..57932
                     /locus_tag="LLC22_000790"
                     /inference="COORDINATES: protein motif:HMM:NF026041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434087.1"
                     /translation="MPMVIRLKKQRYTCKNCRSHWNAQSYFIRPRHSISNHVRHKITS
                     LLTEKVSLFFISKSC"
     gene            58126..58296
                     /locus_tag="LLC22_000791"
     CDS             58126..58296
                     /locus_tag="LLC22_000791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016615560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5434088.1"
                     /translation="MPRLTNYFLSCTNPKEIEFLVTDMNATYFQLTKHVLPNAKLVID
                     RLLGFSTPFKEA"
     gene            complement(58720..59460)
                     /locus_tag="LLC22_000792"
     CDS             complement(58720..59460)
                     /locus_tag="LLC22_000792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5434089.1"
                     /translation="MTKANRLTPGGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGL
                     TTGADGKLAIDGLAPGVYQLVETQAPTGYELDATPIEFEIERSQTAVVELTKENRLTP
                     GGVVLTKIDDQSGEVLQGAVFELQDANGTVLQSGLTTGADGKLAIDGLAPGAYQLVET
                     QAPTGYELDATPVTFKIEKEQEVAIFLTKENRKVADSSDIRGNNPTSSGNKHLPKTGE
                     TIISQFILSILGVLLVFISIKFRKKRNI"
BASE COUNT        17804 a        12169 c        10405 g        19149 t
ORIGIN      
        1 agcaactttt atatcatatc agagagacaa acgattgtca actctttttt aaaagttttt
       61 ttcgatttcg tttttcgaaa tctttcagca actcatttat cataacttat cgtttgttat
      121 ttgtcaagaa cttttttgaa gtttttttcg atagaatcaa gcttcgcaag tggttctttt
      181 taacgactta gttatcttat cacgtctaaa aacatgtgtc aactcttttt tggaattttc
      241 ataaaatgtt tcaatgaagc gcgacaacgt tgtttaatat atcattaaaa aaaataaagg
      301 tcaagctaaa atattattta agcttgacct tattataatt tcaacgattg tcaaaagtat
      361 tgtttgcagc tgtgttgcca gtttctatag ataaatcaca gcttttgaaa cataagtttt
      421 gtactgcttc gattcgcccg aattcttttg cagttatttg gcaatgagaa aagcagacat
      481 cttctatagg cttttcagga aatgctacta aatcaaaagc tcgggaagga agtgagtaac
      541 ctggagaaag gcatgcctgt acgtttttga tgtgtatgtc tttgactttc gtcatttgct
      601 ttgattcagg tatttcttca gccactgctt gccaactttc tggcatttga gcaaggtcat
      661 tgctattttt tctattgtat tcattatgcc agtccattat ccaagaaaaa ggaaattgta
      721 catcaatcat attcagattt tctaccctga tattttcgat cactccccct ctttcttttg
      781 aagatttcat tcgaatacca cagtctgact gaaaaaaatc gatatcgtga atatatacgt
      841 cactaactcc agcactaact tcgctaccaa tagttacacc gtatcctgaa cggattttac
      901 atctagcaac ctcgattctt gatgattttc gattgactct tgcaccattg ccatctctgc
      961 cagacttaat agcaatacaa tcatcaccac aggccaaatc acattcatag acacgcacat
     1021 ttgttgaaga atcaatatca atcccatctg tacttggtcc atcattgttg cggatgatta
     1081 ctttttctac taatacatcg ttagaataag tgatttgcaa gttccaaaaa cctgatttct
     1141 gaaaaatcaa atcacgaaca acaacatgtt ctgcatgata cagtaaacaa gcgcgtggac
     1201 gtttaatagc ataatccgca atccaacgaa gtcccttttg atcgtattca gctcttgtcc
     1261 cgcttttttg atcttttccc caatacagct cccaccaatg gtctccttga ccgtcgatta
     1321 ttccttttcc ttctataaga atatctttcg ccgagagaac attcaaaatc gctgctggcc
     1381 atttcatttc tacgccggct actcgtgtat cgatttctgg aaatgcttcg atatctgttc
     1441 tccccttgag gactgcacct tcttcaaaga taagatgact cttatctttt aaaaaaaggg
     1501 ctccgactaa ataaatgcct tttggaataa atacaggtaa gtgttctttc gcaccttgat
     1561 cgattgcttt ttgcagtatt attgtatcat cttgttgagt gtcgtttgtt ttaaagttca
     1621 aagcattgat aatccctttt tttgtccgca atacgtttct ccctatcttt cattgatttt
     1681 tttcaattct tcaccaataa atacagtttt tgaacgattc agtgggtaac ctactagcaa
     1741 aatgattgcg gatacaaata agcagaatgc tggtaacaag tttgccatcg tataaatcct
     1801 ttcttgtact aaaactgatt ggatggctcc acctgttgta gacgattggt aaccaatgag
     1861 tgccagcata aatccgccta ccgctcctgc acatgcttgt cctacttttc tcgcaaaaga
     1921 atttactcca tatactgttc catcttctct taagcctgtc ttatattgat gataatcaat
     1981 cacgtcagta atgaatgccc agaccatcaa attgaataaa ccagatccta aagtagcgat
     2041 aaataaaaga atcagatata cccatgcatt tgttatatga aggaaataca tcagcaagta
     2101 catacatgaa gaagcaagta acgcaaatac gcttgcttcc tttttaccaa ataattttgt
     2161 cagctttgta gcaaatggtg ctaaaactac tactgttccg taagtaaata aaagagcaac
     2221 agacattgct tgtttattat ggaagtaatc attgaataaa taagtcatat tcgtcccagc
     2281 taaaatctga ttgatcacaa tgaaaatgtc aacaatgact aaaataatca gtgctcgatt
     2341 agctaacaaa ccttttacca actgagaagc agatactttt tcgtttttga caactcttac
     2401 tctttcagta gtcaatttac aagttaacat atatgcgaca aatgctattg cagcacatcc
     2461 gattgaaatc caaaagaaat gattccctga aacgacttgt tgtccactct tgttatgggt
     2521 atacattaaa atcggaatga agaatcctgt agttgatccg ccaatcgcag aaccaatgct
     2581 tcggaacgtg gacaacgagg tgcggtcatt aggatttgag ctaattgctg ctgccattgc
     2641 tccatacggg atattgattg ttgagagaaa aatcccataa acaatgtatg aaacaaaaat
     2701 ataagcaatc ttcaccgtca ttggaagatg ttggacgaat ggcaaaaaca aaatgacagt
     2761 cactaagcaa aatggatact tcatttttct gatccaagga ataaatcggc cagtttctgt
     2821 taactctgag acatcacata atcttccaac catcacatca gcaaacgcat ccaaaattct
     2881 cgaaatcaag aataacgtac ctacgattgc ccctgaaacg ccaagaacat tcgtataata
     2941 aatcatcaag aaactattga ctaaacctaa aataaaacag ttacctagat caccgaacat
     3001 gtagcctatc ttatcggaaa tcccaaattc ctttttttct ttttttattg tatttgctgt
     3061 aacagcattt tgtgaaagca tttgaattcc tcctacctct tctagtaaac gttttcaaaa
     3121 ttataactct ttttttcttg tttttatatt cacaatgttg gctttttatt gcattatctt
     3181 gacagataaa aaacaaaaaa taatctaaaa acattgatgc ataagattga taactttttt
     3241 tacataacaa tatatacaaa caaaaaaatt cactaactag tgaaaataag ttagtgaacc
     3301 tcatttatta aagaattaaa ttacagatga tcttttccat catacttgaa aaactcaaaa
     3361 tcagcataac ttcctctttt tttatttaga tcatgcactg ctatcccgat aaaatttcca
     3421 gtaaaccctc ctgagagtat acacatgttt ttttgcggac ctactttctt ccattcttca
     3481 gttgatacgt ctttcaaatg aaactgtgct gtctctttct ttacagtgac tttcaaaaaa
     3541 gtcttctttt ctgtgagtgg aatcgtccaa tcttctattt gtgctactcc gttttctgat
     3601 tctatcatac gtaggcattt tcccttgtcc tcattccaag taacataaca ataaatataa
     3661 ttggattcat ttaagtacag taccagtcca gccatctgat taaaattatt aggcatgtat
     3721 tcaaatgctg tctccgcatc aaaagtaaaa tccgtttgcc gaatagctaa caaatgatgt
     3781 tcgaaggtag attgaagaga ttcaccggaa atcagacgta aaaaacctgg tctacatttt
     3841 gtatcacacc aatcagcatt tggcaaaatg cgtctggcat tccagttctt ctttagctct
     3901 ccttcaaatg tatccataaa ctgatgatct ttttcttgtt gtacctcttc atttgtctca
     3961 atcattattt cttccatcgg agttgtctgg ctatctttaa gtcttaacca atcgtcggac
     4021 gtccaataca cttcttgaat agcggtttct cttcccaaaa tagccgcacc gtttaatggt
     4081 ctggtacaaa gatatgtcat gtaccatctt cctgacgggg tttgtactaa gctcccatgt
     4141 cctgtacatt gcaatgtaga agcaggtttg tcactagctg tcagcatagg aaaaccagga
     4201 tcaagctcgt aaggaccagt aatattcttt gctcggcaaa ctgtaactga atgtcctctt
     4261 cctgtaccgc cttctgccgt catcaaataa taatacccgt tacgaaaata caaatgtggt
     4321 gcctccgttt tcgctaattc tgtacctgca aatattttat agatgggacc atcaagcttc
     4381 ttcttctctg catcatattc ttgtaatacg ataccgctgg atttattcgg tgtgtccaga
     4441 cgataatccc atagttcatt gacaagccat ttttttcccg tttcaagatc atggaacaaa
     4501 gaaggatcaa agccgttact atttaaataa attggttcgg accaaggacc tgtgatctca
     4561 gatgcagtga tcaaataatt gtggacatct ttaaacggac ggcctgcact tttgacatct
     4621 gtgtaaacaa gataaaacaa tccatcagca taactgatct gtggcgccca tatacttcca
     4681 tttgtaggat ttccttgcaa agatacttga gtggtcaaaa tatccgttgt atgtgaccag
     4741 ttgactaaat ttttcgactc atatactcgg attcctggaa gccattcaaa agaggagaca
     4801 ataatgtaat accgctcttt cactcttaat atattaggat ctggattgaa tcctcttaaa
     4861 ataggatttt tcactttgat agtctgcatg attcaggctc cttttctcat tcttactcga
     4921 tataaactga atgccccagc tgcgaaataa aaaaatgcaa aaggaaacgc aataaactga
     4981 gtgccaatca acaatatgaa tcctgttata aaatacaaac cagtggcagt tgttaagtat
     5041 tttcctttag cagtcaaaaa caatgctact gctaaaaaag caagtgaaat aaacaacaca
     5101 acggcaaaca gaccagtcat gtcctgtaat aatccaaatg tattttctaa agacaaagtt
     5161 gaatgatcta cagcaagcga ctgataactt tttttaaact ctgacgcaga catattactt
     5221 aaagtaactg ctaacccgcc aaagaaaatc aaagatagac tgccaccgac cattcctagc
     5281 aatagttccc attttctttt catttctgaa ccccctgctt ttctaaatgt atccattcag
     5341 gtcttttgat cgatgtttca taattgttat tacgttcaga gaatttgaca gtctgttcat
     5401 ttttcttgtc atcccaatta tcccaaccag ttgggtgaac atgcccacct atcttacacg
     5461 cttcaaataa gacatttgca tacggacgcc acggtcttcc taaatagacg tttctagtat
     5521 caggttctgc agtcaaggta cagctttcaa aacgataccc tgttttttga tttttcggcg
     5581 tagatgctgc tgtgatgtat ccaggatttt tactggctaa gctatggata tgacactgat
     5641 gaaaaacggc atctgcccca ccaaatatga aatccaccgt tccttcaatc cagcaatatt
     5701 cataggtctg acgacaatac tcaggattgg cagaagccgg tgtacaaaaa ggagtaccat
     5761 ctttttgcaa atcaggcaac ggacccgtgc ataaggtatc ctgataacca gatagtcgac
     5821 agttttttaa agatacgcga tctcctgaat tgaataaagc aacagcctgt cctacctttt
     5881 ctcctggacc tgctgtattt tcgatgtgaa gattttctaa tacgacattc gatccttcta
     5941 agaaaaaagt agcacttcgg aaagtcccta actggctacc gtcaagatac tcctgttttg
     6001 caaaacgatt accggagata actactgttc ctgctcccac aagtttaaaa ttggataatc
     6061 tgctttctat atattcatca tatcttcctt cttttactat caagaccttt ggatggctat
     6121 ccggcaggcc tgccaaataa tcgattcctt cttggatagt ttcaaaatcc gtcggggtat
     6181 ctatagcatt ctttccaatt atcagtttgt ctttcatcct cataaatgct cccttatgaa
     6241 ttgtttccaa atatttctca tttcttgtgt ttccatatga ccgcctgtta aagaaaaaga
     6301 agaaaagttt tctggactac ccattgattg atactttttg tccagccctt ttctcagctt
     6361 cagtacgcct tcgtccaagc acatcgtatc gttttttcca actaagctaa gacgagggcg
     6421 cggagcgatt ttttcttgga ttgctaacgt tgtataagct gtcaatagat ttggcacata
     6481 gtaataaaac ccatgatgat ctaggcggcg atgtagcaaa agtatttcga tgtccacctg
     6541 tgccgctaga tcaatacaaa ctttgacacg agaatccaat gctgtcaccc accagcttaa
     6601 taagcctccc atagaaagac caatcgttgc gagccgttga gtatctgtgt cttcccttgt
     6661 ctccaaataa tcgatcaagc tgatcacatc ataaatacgc attccccata acgtttttcc
     6721 tgttaataaa aattgtttga acaactcgct ttcagaaata cctccgcgtt cttcaaatcc
     6781 ccaagcatca atcgaccaaa cagcatatcc cattcctgtc agtacttctg caaaagatgg
     6841 agaagctaag taaggagcac catggatcaa ttcacttttc ccgactgaaa aatctccgcc
     6901 gtgagaatgc aggtaaagga ccggcggaaa cggtccttct ttttctggat aagcatagag
     6961 ggctggtact gtttccaatt catttaagta caattgatag tattcaagca taaaaccgtt
     7021 ttgtttttct cggtataatc gttttccact aggggtatgt ctgctagatg gagcacctaa
     7081 aaaatcattc aactgcataa gcaaagtttt tacgaacaac cagttcatcc atattttctg
     7141 attgatttga ttggaatttc tcaatactga tttctttagt attttctaat agaaatgctg
     7201 gtccctcgtg attttcaatc gacatctggt taaaggaaac cttacccgca aagccaatat
     7261 aaaatccttg tctgctcatt tcctctattc ctgtcatcat agcaggaaca ccgggaactg
     7321 catcttgggc catcgagaca tcgatattgt caaatgtgat ttcttgtatg aattgttccg
     7381 ctaatccata aataaaacct gcagaagcat ggacattcct tgccgtgata ttcgaaaaat
     7441 ggatccttct gaatgctggt gtccgttcat ctatcggata agcctttttt tcccatacat
     7501 acggttcttt ccctcgcgga ccacagaaat aataaagatt cagtataaat ggacacatca
     7561 cattatccat gactatattg gatactcgaa tatcttcaac gatcccgcct cgacctcgtc
     7621 tagatttcaa tcgtattcct cgatcagttt cttggaagat acaatttgaa atggtaatat
     7681 tacgaatact accactcatt tcacttccta atacgacacc gccatgtcca tggaccatcg
     7741 tgcaatttgt gatcgtgata ttttcgcaag cgatcctttc gtacgtatct tcagtccctg
     7801 ccttgattgc aatacagtca tctcccacgt caatatggca attactaata cgcacatttt
     7861 tgcatgattc tggatcaatt ccgtctgtat ttggtgaatc cgctgggttc aagatcgtca
     7921 agttatcaaa cgttgcatta ctgcaaagaa tcgggttgat cgtccaactt ggtgactgga
     7981 tcaatttaat atctttcaca gtaattcgat gacagttatg gaaactcatc aatttaggac
     8041 gaggataagc gagattatct ggttcatttc taaaagtatg ccaccatttt tttccatttc
     8101 catctaatgt accgaaacca gtgacagaga tgttctctac attttgagca tagatacagg
     8161 aagcataaac ttttcgatgg actccttccc aacgtgaatg aacaacagga taatcttttg
     8221 gatcgtcaga gaatttcaga accgctcctg cgcttaaatg aagttcgaca ttgcttttta
     8281 aaaataaagc tcctgttaga aattcacctg ctggaacaac tacggtcccg cctccgtcac
     8341 ttgctgcagc atcaatggct tgttgtattg cttcagtatt caattcatca attgatgcgc
     8401 caaatgtcaa aatatcatac atatttataa tgcctccact tcaatcaatg cttgcaagaa
     8461 tgcaccaacg cctttttgat cattacaaat aattggttca ctgatgtagt aagcatatga
     8521 accatctcgc tgatctgctc cgcctaaccc tgctacttga cagtttttat tcaagttcag
     8581 ccagccttct tttgtttcca gaacaaattc atcaagtaat ccttgatgtg atttcttcac
     8641 ttgtggaagc cattcttctt tgttcagcag tcccaaacgt attcctttag ccattgcgta
     8701 aacaaacata ctactgccgg aagcttccag ataatttcct ttccgttttg tttctgttgt
     8761 tacttgatac catgtcccgc tgttttcttc ttgatatgga agtaatgcag ccagtgtctt
     8821 ttctagaatt tctttcagca aagaacaatc tgtttcttca tgaagtaatt cataggtatc
     8881 tgctgcagcc atcaaatacc agccaatcga tcggctccaa aaatgatggg atagacctgt
     8941 ttttggatca gcccatggtt ggaccttctt ttcatcccat gcatgaatca gcaaatttgt
     9001 ttttggatcg aatagatgtt tataactgat ttcaaactgt ctcaaaacat cttggtaatc
     9061 tttttcttca ctaaaattct ggataaattc agcataaaaa ggagaaccca tatataagcc
     9121 atccaaccaa atttgataag gataaatttc tttatgccaa aaagctcctt cggatgtgcg
     9181 tggatggttt gccaactgct gggaaaggag ttctgctgct tttttatatt tttcttcgcc
     9241 tgtttctttg tacaataaaa agaaaagctt tcctgtattt acatggtcga tattgtattc
     9301 ttcaacgctg tagccacgga tcgttccatc ttcttgcacg aaatagtcga tattgtcttt
     9361 tatgaaatca aaataaattt tttcttgggt tcgttcccaa agtaattgga accctttaag
     9421 tacgacgcca tagtcataag accattttcc tttataccac ttttcttcat ataagcgagg
     9481 tgttctttcc atgatacttt ttgctaattt ctttgaccag ttttccatta tttgctctcc
     9541 tttaaaaatt aaaataggat ttgggacaaa taccaagaag tatttgtccc aatcgtctat
     9601 attactgtgc cgctgctttg tatgcttcct cgtactcttg tgtgattcga tcgcctcctt
     9661 gtgctttcca gtcttctaca gcttttttga atccatcttc gtcaagctgt cccatgatgt
     9721 attgcaccgt agcatcaatg acgatttttt caatttctga tcctacttca ttgttcgtcg
     9781 gtgaatccaa tggcacagaa ggatccatta cagcaaattc ttcattttct ttgatcaatt
     9841 gattagagaa ttctttttca gggtctgtat ctttgaaaga gaacgtcact tcactaggac
     9901 gagagcttga taacggttgc acctcttgtt gccaaagatc catatcgata aattcgatag
     9961 aaccatcatc attcaattca taatgcgttc cttcgatacc gccagtcatc aatttataca
    10021 catcttcttc taaaagatca tcaacaaatt gaagtaattt cttcaattgt gcttcgtctt
    10081 ttacttgaga tttgggaaat gctagcaagc cgccaatacc atttccttct gaccaaacat
    10141 gataaccgcc gccttcacca tctgagatct tgtttacagg cactaattcc atatcatctt
    10201 gaataccttg acccatcgtc ttcagattct tgatatccac cattccagtg tagattccag
    10261 ttcttccttg tgcaaattgt tcttgctgat cagtcttttg ggtaactgca aagtcttgtg
    10321 ccaaatagcc attctcaaat agatctcttg aaaaattcaa agctttcata tactcttctg
    10381 tatcaaattc tggagtgaat ttgccattat cgtctacagc ccagccattt ggtgctccaa
    10441 aataagaagt gaaaagttta aagctggtat aacgaatatc actaggcgca cgatcgccaa
    10501 aaccaactgt gtcgtccaca ccatttccat caggatcgtt ttctgtaaat tgtttagcta
    10561 cttcataaag ctcatccatg gtagttggaa catctagtcc tagattatcc aaccagtctt
    10621 ttcgaatgac taagccagca cgagcgtagt ctttttgtat cggtacgccg tacaaggcac
    10681 cgtcgatact cgcagcttcg attctatctt cagaaatttg acttaaattt ttatagtctt
    10741 ttaaatattc tgatacatcc cagaatacgc ctgattttaa cgcattgcgg acagaagagt
    10801 ttttcaacat cgcaatttga agtgtaacga tatctcctag ttcatcagaa gccaatgcag
    10861 ttgttaatct ttcttctttt gaagcatcag gaatccagtt gaatgtcagt tccgtatcgg
    10921 ttttttcttc gatcaagttc acaatcgtgt ctgtaggcgg tgaagcatga tgcaaaatat
    10981 ttaaccaagt gattttagct tttccatctt ctgtctctga agaactgtta cttgaactgc
    11041 tgccgcatgc ggcaagtgct agaattcctg caaaactaag acctaatttt acgagcgttg
    11101 cttttttcat aaattttctc cttcactgtt ttaataatat ttttgttttc ttctgttttt
    11161 tctgtatatg agttcttcca ttccaaatgg caaaatatag aatttgctgt ccacgtgact
    11221 gcggaaaaga agagactgcc accgataaag gttaaaacac ctggcattgt ttggatgatc
    11281 atcagataaa tccctaccat acttaatatc aacactaatg agtaatgaag atgtgagaat
    11341 ccgaataaaa atgccatttt cattttgaaa aaatatcctt tccaatcata atgagccatg
    11401 attgggaaaa tatagagtgc tgagagcaca tatatgaacg cagcaatata caaagcgatc
    11461 ctaagatacc aattgtgtat gaaagaaaga tccacaagta aaacaatccc gatggcgcca
    11521 tatatccagc tcatcagcaa ggtttcacga tagttttctt taaaatatgt gaagtacgtt
    11581 ttcgtcaaag gaaacgtttc ttttgagcgc agccattttc taatcactgc aaccatcgca
    11641 tacgatgcag gaccgaaagt aaaaactccc aaacctgcga tgactaaacc gccccacaga
    11701 aaattcaaat aaaccaactg taaaatacga tttagccttc cgtttatttt atctaatgac
    11761 tgcagcatat ctttccctct ctttctatct tagtaaacgc cgtcttctcc tagctttttg
    11821 gcaatcttat tagctaaaat taccataaac aatcctacga cccctttaaa caatcccatt
    11881 gctgtactga aacttaactg tccattcttc aatccagctg tataaatata ggtgtcgaaa
    11941 atttctgcaa cgcttcgatt caatgaattc aataacaagt acatatgctc gaaccctaag
    12001 tctaatgtct gaccgatttt tagaatcagc aaggtaatga ttactggacg aattgccggc
    12061 aatgtaacat gccatgtttt gcgtaagcgt cctgctccat ccatttctgc agcttcatac
    12121 aactgtgtat cgactgcagt tatcgctgaa aggtagatga tcgtagacca gcccaactct
    12181 ttccagatca cttgtccgat atatactgtg cgtgtccatt caggggatgt tagaaaactg
    12241 attttttcaa atcccattgt tgcaaggaat tcattcaata cccctccgtc aacattcaaa
    12301 aatacataag taatcgaaac aatgattacc caagacatga agtgagggat gtaaatgatc
    12361 gtttgaatcc cgtttttcaa tcgtttgttc gttacttcat ttaatagtaa agacaaaatg
    12421 attggcatcg gaaaaaacac gaagatattt aatccgaaca agatcaacgt atttcttaat
    12481 aatgtaaaga atgtcggttc tgtaaacaaa cgaatgaaat gtttgaaacc gacccaagga
    12541 cttcccatta ttcctaaaaa tggttgataa tcttgaaaag caataacgag tccccccata
    12601 ggaagatacc taaaaatcaa gaaataaagg actcccggca gaatcatcac atataaaaat
    12661 ttattcgttt tgattcctgc aattattttt tttcgtcttc tgagcttttc ttcttttttc
    12721 gatagcgtca gttgaaatgg ttcttgtttc tttacacttt ccataagccc ctccttagtt
    12781 ttgtgaatgt ttgctgctta tgacttcatg atagataact atctgaatta cgtatataat
    12841 catttttacc gtaagtaaaa acgcttacat agcaatgatt tttgtgctat acaaaacgat
    12901 aaagtgtatt ttttcacaaa taaactacgc atagcaaacc ttctattttt ttctatctga
    12961 cacttagcat aggaaatgat tatatacgta atctttcacc gatgataaat tgaacatata
    13021 gaaacagaaa catttaattt attttgagga ggagcctatc tatatgaaaa agaaagtctc
    13081 tataggagaa agaagtttta cacttttcaa caatacgttt ctaattttgc tagctttgat
    13141 ctgtatcgtt ccttttttaa atatcatcgc tacatctttt gcttctacac aagaagtcgt
    13201 cgcgaaaaag tttatccttt ttcctactac cttttcttta gacgcgtatc gctacattct
    13261 ttctacgccg accattttta gagcacttgc tgtttcgatt ggtgttacag gtgtcggaac
    13321 gatcgtcagt atgtgtgcaa cttcactgat ggcctacggt ctttccagaa agtatttgtt
    13381 tggtcgaggt ttcgtcaact ttcttgttgt attttctatg ttgttcagcg gggggatgat
    13441 tccaacgttc ttagttgttc gttctctagg gctggtcaat tcttactggg ccatgatcct
    13501 gcctgtggct gttaatgcaa tgaatatgat cattatgaga aactttttcc aagccttgcc
    13561 ggatagtttg gaagaatcag caaaaatgga tggttgcaca gattttggtg tatttttcaa
    13621 aattatgctg ccattagcgt taccgtctat tgctactatc tcgctttttt atgctgttac
    13681 ttactggaac acttatatga ctgctatttt gtatatcaac gattcatcta aatggccgat
    13741 acagattctt ttacgccaaa tcgtcattgt atcaagtggg atgcaagcag aaagtagtgc
    13801 cgttgatgtg attccaccag cacaaacagt taaaatggct gttatcgtta ttgcaacagt
    13861 gcctatgctg attgtttatc cttttgttca gaaatatttt gtcaaaggag cactcgtagg
    13921 ttctgtcaaa gggtgattat gtactgaacg caaaatggta gttgtgtcag aagtggtcag
    13981 cttcaagaaa taagaaggca tttacgaaaa ttgcttctta aatttttgtg aaatttcggc
    14041 ttatttttcg aagaatctac tcctggaaca ccgtgtatca gaggttgtga aagagacgtt
    14101 cagccttgag cgatgataaa aactctcaca aacattgcga cgagtaaccc acaggagcaa
    14161 taagaagcga ttttgaaaaa tagcttccca tatttcacaa aattatgcct tattgtcgat
    14221 agcctgtctc ttgaacgcca tttattcgta aaaaagaact gtgacaagac ttttgtcaca
    14281 gttctttttg cgtgcttagc cttgaaattt aactatccat aaatacaaat actagggtta
    14341 ttctaacttc ttttattgct tgaatcagtc cacaagaaaa acagcctctt gattcacaaa
    14401 tatttttttc gatattctcc cggcgtaatc gattccttct ttttaaagaa acgaataaaa
    14461 ttttgcggat ttcgatattg caatctttct gcaatctctt ttacggagag gttagtctct
    14521 ttcaaccatt tttttgctac ctctaaacga tgattttgaa caaaatcacc aaatttttct
    14581 cctgtttcct ttttaaatac attacttaaa tagttagggt tataatgcaa cctatcagcg
    14641 atcacatcta aagacagatc acgatcatat tctgtgtaga cgatatgcat aatattctcc
    14701 gacaaatttt taaattcatg atcagtgatt gcttgagagc attctgtgat tggcagaact
    14761 aattgttcta aaacaagttt ttctagttct ttgggatgat aattgttcag tgcttttaca
    14821 taaatttgtt tcatgttatc aaagtttttt gaatctactc ccaataactg tcctaattga
    14881 acgagttcat tgatcaagcg gaccgaaact acttcccgac tcaaaggatt tttattttgt
    14941 gcaaacaatg catcaatcaa ttcatgtact aaattcttca cttcctgatt tccagaacga
    15001 atggcttcaa acaatcgatt ttgttcttct atcggatatc taataagtgt tttttcatga
    15061 gcagcaggaa cgatttcctg ataaaaaata attgaacttg gaccagtatt tacacgataa
    15121 tacagggctt cttttgcccg atcaaccgat tgcttgcttt cattcagcgt ttcgaaccgg
    15181 ttactgatgc ctatactgat agttaaattc aagtattctt ttacacgttt ttgaatgagt
    15241 cggcaatact ccatgacttt tttgcttgct tctgcatcat ctttatccat tcgataaata
    15301 gtggcttgca tttcttcatt caaaacgatc ggcagcattc gattttcctt tggcacaatt
    15361 tccgtgatca tgttgttgat cgctaaaagt agcaaatcac gctccccacc gtgactatct
    15421 tctaacagat cgatttgaac caaagctgta taatagcagt cattttgaga actataacca
    15481 aattgctgca accgctgatc tagttctcgc ctttctactc gatttctaaa taaactaagt
    15541 acaaatagcg tttccagctg tggcttttgg gtaactaagt gtgcacttaa cgcttctttt
    15601 tctcctatga tccgactgac tgattgagcg accaaatcta gttctttccc actgaatcct
    15661 tttgatttaa gattcagacg ttcctgtatt tgagaaatcg gacgggcaaa tctgtccgaa
    15721 aataagtagg aaagaagacc aatgagtcct accagtgtta aagacactgc aactagcccg
    15781 attctcagat tgcggatcat tgcgccaatt gcactagagt caacttctaa tctgtaaatc
    15841 caattattat aatctgattt cagtactata tacgttttat ctttttctct tatcactttc
    15901 agctgattgt aatctagatc cacgtccgtt aatacagttg gttgctcttt attttttact
    15961 gtctgagtag taaaaaggtt gccaacttcg ttttcaatag aaagtatgtc ttctccactt
    16021 tcaccaacaa cttgttctat tgtatgtttc tctatcgtag caattcccaa tgcatatttt
    16081 tctttttcaa acattggcaa agaaatcacc atttcgattc ctttgttttt cttttgccaa
    16141 aataaattat ttttgttatt tatgtacttc tgttgatact tttcaatttc ctcttcggtc
    16201 agttgactca acgatccatt gattactccc catttaccag ccaaactgac taaatcataa
    16261 ttattatcat ccataacaat cgtttctata aaatttagtt ctttcctgat ttcagaataa
    16321 gtggagtaat ctgtatatgt cagcggatgc ttgaatatgt ccgagaaatt tttggtcgaa
    16381 ccatacgtag aaaacgaata ttcaatcgtt ctaattttcc attcaacgtt agttttaact
    16441 tgcctgagca aattcttttt gtctgttaaa taactcgatt cgatcgattc ataggtattc
    16501 tggtaaatga ataaactaaa tcctatgaca agtacggctc ctaataaaaa catcggtaaa
    16561 aatattttat aaaatactgt acttttcttc attttcttcc tctcctcctt ttaaaataaa
    16621 aggctttcat ttttctgtaa aattgatact catctaatta aatgagcatt ccccgctttc
    16681 aagaatagca taattaaaaa taaaaatcca agtaattttt aacgtgtgca atcttttcat
    16741 atcaaagatc tattgactta tcgtagttat cgtaatatga tgaatgcgtt aacaaaaagt
    16801 gaaaaagtaa ggaaaatgat ggaatggtaa cgatcaaaga tgtcgctaaa gcagctggcg
    16861 tttctcatac gacagtttct cgtgctttga ataacagcag tttaataaaa aatgaaacaa
    16921 aacaaaaaat acgacaacta gctaaggaaa tgaattattc gccaaactat agtgcaaaag
    16981 gtttagtgaa tcaaaaaaaa tatctaatcg gactattttt ctcaagtttg cataaaggaa
    17041 cttcatcaaa tttcctagca gattccattg caggcatcca ttcagtatta gacacaaatt
    17101 acagtttatc tgttgaaagt atcgatgttg ttgatttaac agaaatcaac ctgcaacgct
    17161 acgatggact gatcgttatg agtcaaagtg atgatgatca gcctttcatc gactatctca
    17221 aagaaaaaga atttcctttc gttgttgtca atcgtcacat caatgatcca gcggttatca
    17281 acgtcactgc cgatgatgcg gccggtgtta tgcaggcagt agattacggt attggatgcg
    17341 gacatacgaa gatcgcttat attggcggaa agaaaaattt tcgttcgaca aaagaacggg
    17401 aaaaaggggt attgaaaagt ctaaaaaaag cgagcatccc tgtcaatcca gcctattttt
    17461 taacaggaga ttacagctta gaaagcggcc tccaaaacat ggaataccta ttatcacttt
    17521 ctgacctgcc tactctggtt ttttgcggca acgacgacat agcgattggt gcattgagag
    17581 ctgtacattt agctggcctc cgtgttcccc agaacatttc tctgatcggg ttcgatgatt
    17641 ctccagtcgt ctcctatctc aatccgccgc ttaccaccgt acgtaagcct ttgaaagaaa
    17701 tgtgtcaaga aggaacaaag cttttactag atttgatcga aggcaggacg atcgaacaat
    17761 ctaaaattga gctctccacc ttgttgatcc ttcgtgagtc gatcaattac ttgtaaacta
    17821 caagtaattt tatataaaaa tgttaacgtg tgcataacac agaaaggaag tttatatgaa
    17881 aaaactgaca aaagaattag tgaaaaaaaa cgaagcacct gtaaaagttc ttcagtttgg
    17941 tgaaggcaat tttatgcgtg gatttattga ttggcagatt cagcagctga ataaccaaca
    18001 attgtttaaa ggtaatgttg caatcattca acctttagaa caaggtcttg gaaatatgat
    18061 gaaccagcaa gataatttat atacggtcat tttacaagga ctcagcaatg gcgaaatcgt
    18121 tgatacttcc gagattatca ccgtagtaga acaaatgatc aatccttatg atgaatggga
    18181 tgcttatcta tctctagcag aaaatgacga cttggcctat atcgtctcca atacaacaga
    18241 ggcaggaatc caattcgtgg agactgataa tttaacagat actcccccac agagcctccc
    18301 gggcaaactg acagcctttt tataccgacg tttcaaatta aacaaagctg gctttaccat
    18361 cattccttgc gaactgattg acagaaacgg cgaacgtcta aaagaaatca ttttacgcta
    18421 cgcagaaaaa tgggatttag aacctgcttt tgttgagtgg ttagaaaaag aaaatgtttt
    18481 ctgttgtagt ttagttgatc gcatcgtccc aggttatcct cgcgaagatg caggtgtttt
    18541 caatcaacgg cataactatg aagatcaatt gatggtcaaa gcagaaccat tcatgctttg
    18601 ggtgatcgaa gggcctaaag aattggagaa tcaactacca ttcaaacagg ctggcttgaa
    18661 tgtcatcatc acagatgata tgactcctta tcgtgaacgt aaggtgcatt tgcttaatgg
    18721 accgcataca gcgatggtcc ctcttgcttt gttggcggaa ttggaaactg tagaagaagt
    18781 aatgaaagat cctttattct ccgcatatgt tgatcagtta ttcaatctag aattgattcc
    18841 tatgctttct ttacctaaag atgaattagc catttatgct gaccaaatca aagaacgttt
    18901 cttgaatcct tttgcccatc acaaattaga agcgatttca ttaaatagtg tttcaaagtt
    18961 cagcacccgt ctgcttccag tgttcaagaa gtatatcgaa gaacaaaatc aggtaccacc
    19021 gttaatcact gtttcactag ctgcgctact tcttatgtat cgaggcgatc aagtaaagcc
    19081 acatgatgat gaaaagacga taagcgaatt tactgatgct tggtctgata atggaacagc
    19141 tattcctcga ttattgcaaa acgctgcgct ttggggagaa gatttgtctc aaataccgaa
    19201 tgtgacagat acagttcaag aaatagctgc aaagatcgat caaaaaggtg tccggtcagt
    19261 attacaagaa atgaaaggaa cgatggtcca tgcttgaaac cctgcaacca acaatgaaat
    19321 taaatcgacg agacagtgtg gtcgtcgcat taacccctat tccaaaacaa acacaactga
    19381 cgattgatca gcaaacgatc accactcttg aagatatccc gcaaggtcat aagattgcat
    19441 tgggtgattt gaaagctgga gacaacgtga tcaaatatgg ctatccaatc ggtcatgtga
    19501 cgacagacgt aactgccggt caatggctgc acactcataa tgtaaaaacc aatctttctg
    19561 gtgaattgga ttatcgatat gaaaaagatg tccatccaag tcattacctt tttgagaacc
    19621 gaacatttca aggttacttg cgaaaaaatg gaaaagtagg gattcgtaat gatttgtttt
    19681 tagtacctac cgttgggtgt gtgaatggca ttgctgaact gatcgtcaaa cagttcaagg
    19741 aaaaacatcc agatctggga cagtttgacc atattacgat tttaaagcat ccttatggct
    19801 gttcgcagct tggaaaagat catcaaaata ctcgagaaat tttagcggac gcagtaaatc
    19861 atcccaatgc cggaggagtt ttagtatttg gattaggttg tgagaacaat acagttcctg
    19921 aattcaaaaa aattttaggt gaatatgatg aagaacgagt gaaatttcta gtggctcaag
    19981 atgtttacga tgagatcgaa caaggtgtgg ctctattaga agagctttta acagcggcgg
    20041 aaaatgacca gcgcatatca gtcccgctct ctaagttgaa tgtcggtttg aaatgcggcg
    20101 gttctgatgg tctatcggga ataactgcta atcctttact tggtgcattt tctgactact
    20161 tgattgctca aggaggcagc acgatcttaa cagaagtgcc agaaatgttt ggcgcagaac
    20221 aagtattgat ggcacgagcg gaaaatgaag aagtttttga ctcaatcgtt gacttgatca
    20281 atgacttcaa acagtatttc ttgtcttacg gggaaccagt ttacgaaaac ccatctcctg
    20341 gtaataaagc aggtgggatc actacattag aagataagtc tttaggctgc acgcaaaaat
    20401 caggaagctc tcctgtcgtt gatgtgctac aatatggcga aaaaatcaga aaaccagggc
    20461 ttagtttatt gcaagctccc gggaatgatc ttgtagctgc ctctgctctt gcttcatccg
    20521 attgccagtt ggtcttgttt accacaggaa gagggactcc gtttggctca tatgtcccaa
    20581 cggtcaaggt atctacgaat acaactcttt ttgaacgcaa aggtcattgg atggatttta
    20641 atgcaggcgt cttattagaa caaccaatgg aagtaatctt agaatcgttt gttcaaaaaa
    20701 tcatcgctgt agctagtgga gaagaaacga aaaatgaaca aaatgacgtt cgagaaattg
    20761 ccatttttaa aaacggagta acactttgat tttcataaaa cagtataaaa agaaagaagg
    20821 aagatttatg tttttatctg atgatttttt attaaaagac gattgggcga aaaagcttta
    20881 ccattcctac gcaaaaaaca tgcccattat tgattatcac tgtcacttag atccaaaaga
    20941 aatttacgaa aacaacaatt tcagcaatct gacagaagct tggttaggag gcgatcatta
    21001 caaatggcgc ttgatgcgag cttgcggcgt gcctgaagaa aaaatcacag gaaatgcttc
    21061 tgattttgaa aaatttttag cttggtgtca aaccgtacca aaaattatcg gaaatccgct
    21121 ttacagttgg tcacatcttg aattgaagcg tttcttcggt attgacttgt tgataaatga
    21181 agaaaatgca gagaaaattt ggacacaagc aaatgaaatt ttggcagctc ctgattttcg
    21241 ccgtcgggaa atcgcaaaaa aatcgaatgt agaagtgatt tgtacaacag atgatcccgc
    21301 agacgacttg cactatcatc agttgcttgc tcatgaagaa ccagatttga aggttctacc
    21361 ttcattccgt ccagataaag cactcaatat tgaaaaagaa ggatttaatg catgggtcac
    21421 actactggaa gaagcagctg accaaacgat caccacctat caagaactga tagaagtctt
    21481 agggcagcgg atagaatact tccatcaaca tggatgtcgt gtttccgacc acgctttaga
    21541 catcttacgc tataaagaag cggatgaaac agtattagaa gagatttttc aaaaagcacg
    21601 agctaacaaa ctattatctt cagatgaaat cgatgcttat cgtacagaaa cactgataca
    21661 tttgacccac ttctatcatt ctcataattg gacgatgcag ctgcacatcc atgcttatcg
    21721 taactgtaat acacaaatgt tggaaaaatt agggcccgat accggctatg atggaatgaa
    21781 tgatctttct ttgactattc ctctgcaaaa attattgaac cgtgcagaag aaacggatca
    21841 gttgccaaag acgatccttt attcattgaa tccgaatgac tatcctgcga ttttagcttt
    21901 gatgggctgt ttccaaaaag aacagaatgg aaaactgcag ttaggttctg gatggtggta
    21961 caacgatact cgagctggta tgcgcgatca attgacacaa tttgctgatg gtagtgcttt
    22021 ggggaatttt gtcggcatgc tgacagattc aagaagtttc ctgtcctaca ctagacatga
    22081 atatttccgt cgtgttcttt gtgaattttt aggcgaaatg gtcatgcgag gagaagcacc
    22141 tgaagatgaa caacttttag gaagtctagt tcaagcgatt agttatacaa atgctaaaaa
    22201 ttactttggc ttttttgcct aattgattaa tagtaacagt aacgaatcaa aaacaggata
    22261 gtgaaataac ggaatccgtt tatccacgtt ttagagaaga agacggacca aatttgctcc
    22321 gtcttcttct cttgctgttc tgcttcattg cctataaacc tttatgaaag aagagataac
    22381 atgcctacta tccatattgc cggtgattct actgcggcag aaaaagatga aaacaagcgt
    22441 cccgagacag gttggggaga aaaaatctct gcttattttt cacccgagat ccagatcaat
    22501 aaccaagcaa agaatggacg cagcaccaaa tcatttatcc aggaaggaag gttagcccgt
    22561 ctagcttcac agtttcagcc gaatgatttc ttatttgtac aatttggaca taacgaccag
    22621 aaaatccaag aagaaagagg tacgcttccc ttcggtagct atttaaaaaa tctgcagata
    22681 ttttttgaat gcgcaaaaaa agcgaacgtc caaatggtct tactgacatc tgtgacgcga
    22741 cgagattact tagaaaacgg aacattgaat ccagatatac ttggagacta tccaaaagcg
    22801 atgcgtgcat ttgctgagaa acaccatatt cctcttttag atgtgttctc aagatcacaa
    22861 gaattgttcc agaccttctc aaaagaagag acaaaaaaat tctacctgca tcttatacct
    22921 gatacttgta aaaattaccc agaaggacta aaagacaata cccactttag tccagaaggc
    22981 gctgataaag ttgcccgaat aattgttgaa ttgataaaag aatcccgtct gcctcttgct
    23041 aattatttac aaaaaggagt ttgagatgtt tccattaaat ttaggcatcc gtgcccacga
    23101 tttagatgtt cgaaatcgtg aagaaatcgt tcaaaaagta tcacagcttc acttgtccca
    23161 tatccaattt gcaccacaaa aagcatttcc tgaacaactt aaattaactg acatgacact
    23221 tgggagtgct gcctattttg gtgaatactt ccaaaaaaac aatatcgaac tttccatttt
    23281 aggatgctat atcaacctat ccagcaaaaa tcaagaagtt cgtgcacaag cattggcaac
    23341 tttcaaacag caaattgctc tgtgctctgc ctatcaagcc aagatgattg ctacggaaac
    23401 cggtagtgtc tctgtcggtt acacaaaaga aaattttact gaagaagctt atcagatcgc
    23461 cagaaattct atcattgaat tagtcgctca tgcagaaaat tttggcgtaa ctgttgctgt
    23521 tgaagcaggg atcaatcatc caatctataa ctatcagtta gctaaacgtt taatcgatga
    23581 agtagcttca ccaaatttaa aaatcatttt agattgtgcg aatttgatgc ataaagaaaa
    23641 tcatgctgat caggaaaaag tgatccgagg tgccttggac aatttacatg gttatattac
    23701 agcgcttcat ctcaaagact atatcatgga aaatggaaag atccgcatgg tacctgttgg
    23761 caagggctgt ttagatttcc gcccggtact gcattatatc aaatatgagc gtcctctaat
    23821 gtacgccact cttgaagcta ctcctgagat ttatgttcct gaagcaatag aacacttgca
    23881 gtttatttac caagattgtt aaggagaaga ttatggagga acgaatacag aaaagttatc
    23941 aaaaatatca tgcaaatgct tttcagacat tgctgcatct ttatcaggga aattattggc
    24001 gttttgccat gtcaggactc ttttttatta tcaaacatct tccatcttgg ttaatgccga
    24061 tcgctattgc caatgtaatc aatgcagctt catcgaaaga ttcttctcag ttgcaggcca
    24121 tttatttcaa cgcttttttg atggcttgtc tgattggtca aaatatattg acgaattatt
    24181 ttcatgtaaa ataccatagc acttcgatcc gtcaagtaga agctggacta agagcgaccc
    24241 ttatcaagaa aatccaagaa ctatctattc cttatcaaaa agaattgcaa tctggacgaa
    24301 tccagtcaaa gatcatccgt gatgtagaag ctatccaaac gttgtcctct caagtatttg
    24361 tcagcggatt aaatatcgct gtcaatttat tcgtagcttt aggtatcacg ctttataaaa
    24421 gtcctgttgt tttcatgttt ttcttattga ctgttcctct cgccgcattc gttactctct
    24481 ttttccgtaa aaggatcaga cagtccaact cagacttcag gcaagaaatg gaagagactt
    24541 ctgcaaaagt gatcgaagtg atcgaattag caccgattgc tcgagctcat gggttagaaa
    24601 aacacgaaac aactcgctta aataagcatt ttactcaaat ctatgaaaaa ggattccact
    24661 tagatatcct gcaatctgtt ttcggatcag tcagctgggc tagttttcag atatttcagc
    24721 tgatttgttt gattttcact gggatattag ctttacaagg gcgcatccaa cccggcgatg
    24781 tcgtgatgta tcagacgtat ttcacgacga tcgtcaattc cgtttctgga atgatcacgc
    24841 tgattcctac gatttcaaaa ggcatggaat ctatcacttc tattggcgaa ctgttgattg
    24901 ctggcgatgt agaaacttat cacggtaaga aaaaaatcca acatttggat ggaaattttc
    24961 gttttgagga tgtttctttt ctttatccgg actcactcaa accgattatc gatcattttt
    25021 ctctagaggt gaaagctgga gaaacaattg cttttgttgg gccatctggc tctggaaaat
    25081 ctacactcct taacttattg attggattta tccagccgac ttcaggaaaa atttttctag
    25141 atgatcagcc tttggatgaa ctggatatgc gaagtgtgcg aaattattta gccgttgttc
    25201 ctcaaaccac tttgttgttc tccgcttcga tcaaagagaa catcacttat ggcttgaaaa
    25261 acgtatcaaa agaacgttta gatgaagtca tcgaagctgc gcaactttct tcactgattg
    25321 accagcttcc tgatggtctg gataccttag taggcgaaca tggcaacaag ctgtctggtg
    25381 gccaaaagca acgtatctcc attgcacgag cgttgatacg tcagccaaaa atcattttgc
    25441 tagatgaagc aacctcagct ttagataacc agtcagagaa aaaaatccag caagccctga
    25501 attacctgac agaaacaccc actactttta ttgtggctca tcggctttca acgatcaaag
    25561 aggcagataa aatcgttgtg atcgatgaag gaaaaatcgt tgaaataggt acttacgaaa
    25621 aactgttagc tcaaaaaggc tatttctacc gcttgaaaaa tgaatgacaa aaaataggag
    25681 ctatgacaag acttttgtcg tagctcctat ttctgaataa acggtgttct cctgccaact
    25741 cctcggtcac aagtcacaat agtcatcaaa catgagaagc tgttttttga aattgttcct
    25801 tgtaactcag agttaaacgg taggctcacg acctcttggt aaatggtgtt caagagacag
    25861 cctatcggca ataagaagca attttgtcat cgctcaaggc cgaacgtctc tttcacaccc
    25921 tctgttgttt cataaaatag ttttattcgc tgtaaaggtc gcgaactggt gtcatgatga
    25981 tacggttcaa gtcattgatg attgtactga agccttgctc tttttgcatc aagtcattga
    26041 ttacttcttc tgattggatt ttcacagcca tttcttgtgc tttcattgca tcttcgtcgc
    26101 tgaactcttg tccactcatt tgtttttctt gtaattcgat ttgcatcgct tggaagtctt
    26161 tgaacagttt gtgtgcttct tcgtttgctt gtactttctc gtacgcttct ttcaacgctt
    26221 tgaattctgg taattcacgg atctcacgtt cgatttgatt cgcgctatcg tagatgtttg
    26281 acatgttatg ccctcttttc ttttagtagt tactctctat tgtaacatgg ggttattcgt
    26341 tttcaaaggg gctactctcc ttgatatttc cgccagaggt ctttagccgc ttcaccaatt
    26401 ccctgaacgc cttctttcac catatcgccg aagtttttca gcccttcttt tgcttgttca
    26461 ccatattgat tcaagttatc ttgccaattt ccagactctc cattagaatt tcctgtgttt
    26521 ccaacttgat ctgcagctac cacttgtcct cctgtggcat aggcatctgc tacactaaat
    26581 cctgtttttg aagtatacgg aaggatgcct tctgccgctg atttgaagac tttcccgaca
    26641 acatttccac ttgtcccttc caaatagtgc agcttgctgg attcttcgta acccatccat
    26701 gtcgaaatca ctacgtctgg cgtgtaaccg atcatccatt ggtcatttgc ttttgtggca
    26761 tcgaaattag tttctgtggc tcctgttttc cctgctatcg tataacctgc aggattcgca
    26821 gcagccgctg ttccatttga aaatgtacca agaagcatgc tggtcatttc atcggctgtt
    26881 tcctttgata tgacctgttt tggttttttg tttgtgttat cgacgatcac cgctccagtc
    26941 gaatcaacga ttttcgtgat aagatgcggc gtatacatct gaccatcatt ggcaaatgca
    27001 ctgtaagcac ccgccatgat caatggagat actccttttt ccagtccacc aagggctaag
    27061 ccataatact tatcagattt tgctaaaggc aggccgaatt cttctgcttt atcatatcct
    27121 ttttgtaaac cgatctcatg caaaagccat acagtaggca aattcaaact ttgtgcaaca
    27181 gcttgataca tcggtacttc tccttggtat gtcccgtcaa aattatgcgc atcgtaataa
    27241 ctttgcggtt cgtctttcaa gatactggaa ggcttgtatc cagcttccag tgctggtgta
    27301 tatacgctta atggtttgat cgttgatcct ggtgaacgac gcatctgtgt agcaaagctg
    27361 aatcctctaa agacatgatc tcctcttcgt cctactagtg cttgtacacc acctgtattc
    27421 ggatctaaag ctactgaagc agattggacc atggcaccat ctgaagcatt tgctgggaat
    27481 aatgcactgt tttgataagt agcttctaat tgcttttgat aatcctgatc taaagctgta
    27541 tagattttat agcctttatt catgacatct tcttcatcaa gaccatactc gttaactgct
    27601 tcatcgatca ctgcatcaaa ataataagga taacgataac cagaatctga attatcgtat
    27661 gtgtcattaa gatacgcgct gatatctgtc tggctttctg cttgttcttg ttcttttgtg
    27721 atttttccgt tttcttccat tacacttagt actgtgtttt tccgatcatt cgcatttttt
    27781 gggtgatcga tcggattata aataccagga cctttcagca ttcctgccaa agtagcagcc
    27841 tcagacagcg taacattcgt tgcatctact ccaaaatact ttctggaagc gtcttggaca
    27901 ccccataccc cgttgccaaa ataggcattg ttaagataca tggtcaagat ttcttctttg
    27961 ctgtacttct tttcgatctc gattgccaaa aataattcct tcgcttttcg atcaaacgtt
    28021 tggtctaatg tcagatacgc atttttggca agctgctgag tgatcgtact tcctccgccc
    28081 cctgatgttc cgccagacaa gaccattcgg actgctgcac gggcaatccc tttgatatca
    28141 aacccgtgat gctcgtaaaa attcctatct tctgtcgaga ttactgcatc ttggatatag
    28201 ggagaaatcg cgtttaattc tacatatgtt cctttttggg cgtacagtgt gccagcttct
    28261 tcgtttttct tatcataaat gactgtcgat tggcttaatc ctgattttaa cgtttcgaca
    28321 tttgcttgtt ttgctaaaat aaagaggtag atacttgtca ctaagacaca gatcaaacca
    28381 atcagcaaaa tcaatttgtt cacatgatat tttttccaga tgcgctttcg ccatcgatgg
    28441 aattgtccga gatatggtct gatccaacgc caaaaactga tcaaagcagc ttttatcttt
    28501 tctaaaatgc tttgaaaatc catttgcttc ttctcctgtc tatttgattc aatcgtctta
    28561 ttttaccata gtgaaagagt gttttcttcc tgcttaagtt gtagttcaat atgttttttt
    28621 acgttagtgc aagtagagta acataagaat gaacagaaaa atgtaagttt tttcttaaat
    28681 atgttttaaa aatggtacaa ttagtctgcg attgcactga aaggagtaca cttgtgaaaa
    28741 tcacgatcac tttacctatg aaccatcctg aaacaacaat tcgcgacttg cttgaaaagg
    28801 aatggttagt tcctagaaag gttcgacact ttttgcgtat acgtaaaaac gtttggatca
    28861 atcaacaacc tgctttgttc catcatgaag taaagggcaa tgaccagatc acattgttat
    28921 tcgaagaaac agattataat tatcaagaag ttcaattagg agatgcgaag cacatccgtg
    28981 ttttatatga agatgagcat ttgattatag tggataagcc tgcaggaatg aagactcatc
    29041 caaatgaacc gacagaaaac agtaccttac tcaatcattt agctgcttat ctcgacacta
    29101 aacagcaacg accttacgtt gtccaccgct tggacaaaga aacaagcggt gccgttttat
    29161 ttgcaaaaaa tccatttgtc ttgccgatac ttggaagaat gttggaacaa aaaatgatct
    29221 atcggagata tcaagccatc gtatggggag aaattgccaa agatatgacc atcaccaata
    29281 aaattggacg agatcgccat gatcggagaa aaagggtcgt agatgataaa aatggtcaga
    29341 gcgccttgac acatgtcact gtcaacaaag tactttctga acaaacacaa gtctattgtg
    29401 ttttggaaac cggacgtaca caccagatca gagttcattt agctcataag ggacatccga
    29461 tcgttggaga ccctctctac caaaatagaa cagctgaacg actgatgctc catgcattag
    29521 aactgcacat gatccatcca tttactcaag aaaaaatagt cggtaaagct ttacctggat
    29581 tatgggaata gaaataaaaa agaacagagt cttatcagca gataatgata agactctgtt
    29641 ctttttgtgt aatttgtctg cttacttttg atgttcgtgt tctgctaaca gcaaactacc
    29701 gataatccca ctttcattcg gcagtcccca acgaacgata tattcactta cttgaggtgt
    29761 ttccatataa ccacccatca attcaacaaa ttgctgacgg attttttgaa ggagatgatc
    29821 ctgattcatt accccaccgc ctaaaataat cttttcaggt gctaacgtca acgtatagtt
    29881 gatcagtgct tgagcaatat aataagcctg aatagcccaa acaggatgat cttgcggcag
    29941 atcttgccct ttgatccctg tgcgtgcctc aatagacggt cctgctgcta atccttctaa
    30001 acaatcttta tgataaggac aagtaccttc ataatggtca tctggatggc gtttcaccca
    30061 aatatgtccc atttcaggat gtgcgatccc tgaaaaaatt tcttcattga tcacgacacc
    30121 tgcaccgatt cctgttccca cggtaaggta aatacaacta ttttttcctt gtgctgctcc
    30181 ttgcttcaat tccccatatg cagcagcatt gacatccgtt gtccaagcag caggaatatt
    30241 gtagcgttcc ttgattgtgc caagaaaatc gaattgtgcc cacccttttt tgggagttgc
    30301 caaaacgtat ccgtaattat cttttgtttt gtcgatacca atcgggccga atgagccaat
    30361 cccgattccc ttcaattcat aacgatcaaa aaattcaaat acctgatcca atgtttcttc
    30421 tggtgttgtg gtagggatac ttaatttttc taaaatttct ccaccatctg aaaccgcaca
    30481 cacaaatttt gttccgcctg cttctattcc gccatacatt cgttttcctc ctcgaatccg
    30541 attgtccgaa tctcataagg ttggattatt gggacaaccg cttgcttcgt tggttcttca
    30601 agcagattca atatgacagt ttttccattg tctttagtta tttccaattt ttctaaatga
    30661 ctagacatat tgaaacctct tactactact ttatcactaa acttgctgcg tttcaaagct
    30721 gtaattgcaa acgtttcact ttttatcgtt aaatattgtt gttttgaaat caatgttcct
    30781 tcatgatgtt tgatttgttg agtggaaaaa ggaatctgtg ctgcgtatgc atgcaaataa
    30841 gtagagaatt tttcttctgg tccatgtagt tcaatgctgt aattgaaccg atgctcacct
    30901 agacactgtg cttctggtgt tggaaaatat ccccaatcgc ctagttctcc cacactgcga
    30961 agtagcgtca ctgcgatttg tccgtcttct gttacttcat attcattcaa accaaagttt
    31021 ccgactgtta caccgtactc ttcatcatga atattgacaa atgcttgctg atgttgcgga
    31081 ttcgtggggt tttcccaact tttagacaca tggtttgggc gcttcaccac ttcaaaaata
    31141 ctatctgctt cgtgatgttc cacatgtaac tttgtaggaa acaagacacg taagcgatga
    31201 tctttcatct gattgtcgag agtcgtttca aagtcgattt ttttactatc ttttctgatt
    31261 gtcatgattg tttttatttg aaggattcgt ttttctttgg atcgttctgc ttttcgataa
    31321 cgaaattcca caaccatctg ctgttctttt tctaaacgct cgtctgcaga aacagggatt
    31381 tccatttcct gtagaatact tatttttgct atttccggtg tatctactaa tacttttact
    31441 tcagagtttt ctttgttact ggataggatt ggctgatcac agaaaggttg tttaaagata
    31501 tactcatttc ctatatcgcc gatatcttca aaaatatgca gattattcaa ctttcgtttg
    31561 tttttgcgat cttccattgt aatggtacca tttttttcaa tcgtcaaatg tagagggccg
    31621 ttttcgatga ttcgtccact ctgatgaatc attgtttcct tttcttctgc tttcgcttcc
    31681 ccttctacaa gcgcgaatgt ttcccaagaa aatgctggca tgttttctaa tggtaaagtc
    31741 actttgatca ttcttgccat atatggcaca cggaaacggt ctttcggcaa atcataacca
    31801 aattggacag tttcttcaga taaaatagct ggtatagtgg ccccactttt tgtttctaca
    31861 tgatacttac gtttaggcaa attttctaac tcttgatata gttgttcagg tattccttca
    31921 gcgaatcttt ttctttctaa ttcgatggtt atttctgctt caccagtttt atccattcct
    31981 gcagtattta caatgacaaa tggaaagctg tcttttggga atccggtcgt atcgattgct
    32041 gcggtcagct gttctaagga atcttgtgca agatactttc caacttcatc tgctttttca
    32101 aaacgaggta tcatttcccg atggacagaa tcgactgaac aaccgcaaat actgtcgtga
    32161 ggatgatttt gcattaatgt cttccaagca taatctaatt gatcatgggg atagtttcca
    32221 ctaacttcat aagccatcgt cgcaagtggt tctgtaatat tttctagctg tcgctggacc
    32281 ttggtattcc attgttttaa gtaaacccga gcagatgctg tattggctaa agtataccag
    32341 ccatccgttt cttgacttgt caattctcct tctactgagc ctaagtcttc tggcacatct
    32401 ttttgaactg cttccagata gtcagtaaaa ttagaatgaa taaactcgta atctggaaac
    32461 agttcatttg cgagatggat tgcttttgat atatcttttt gtaccggttg atgatcaaca
    32521 ccattcatca tcaataagtg gttcgtagag gcatattgtt ctgcatccgc taatttttgc
    32581 ttccaaaagg caagagctgc ttctttttct actggaatct cattcccgtt gctataccaa
    32641 ttggcaaata gcagaccaaa gattgctgtt tgatcaggtc ctttccacca catctctgag
    32701 tattgggaag aatagttttc tgcttccaaa acttgattat caaagccaat tggttttaca
    32761 ccacggccaa acgctgctgc tgaaatacca gcttgtttca ttaattgagg cgtctgtccc
    32821 atatttccaa atgtatcggg aaaatagcct aacatgacag gggttcccca tttacggctt
    32881 tcttccatgc caatcagcat atttctcacg ttcgattccg agctgataag aaaatcatct
    32941 tgcaagatat aaaatggtcc aattctcaat tttccttcat tgattgcttg ttggattgcc
    33001 tgtctttttt ctggccttac ttgaagatag tcatctaaaa taatcgtttg cccatccaaa
    33061 tgaaaactgt tgaaggacgg atcaacttca aatagctcta gtagatcgtc tatcaattca
    33121 atcagtcgca tgtgatgctg ttcgtaagcc atgtaccatt cacgatccca gtggctatga
    33181 gaaatgatat atactttctt tttcatttac gatacctcct acttttctac tctaatatca
    33241 aagtaatcca tgactaattc gcaaaacatc atatttgccc aagaaaacca ttctctcgta
    33301 taattttcag gattgttcac atcgaatcct tcgtgcataa ggtgtgttcc tgcgtcagtt
    33361 gctacaagta aattcaatat ccgctctttt tcagatttgt ctgacgttgt cattccttcc
    33421 atagctaatg caatcggcca aacgtatttt tctggcgtat gggaggatcc aattcctttt
    33481 gcgtactttc cttcatagaa atatggattt tctttactca acaatgttct tcttgtttgc
    33541 agataatctt cctcttgttc agaacaatat cccaagtaag gtgcggcgat cagattgggc
    33601 acattactgt catccatgac tgtggcgttt cccattccat ctacttcata tgcataaatc
    33661 gtttgccctt tttgattaac cgttcgtccg tgattctgaa tcccctcttg gatctctttc
    33721 ttcaatttct gtgtttgctg tacaatttct ttatcatcga gtatcgtttg aaaaatttct
    33781 tccacataac ctaacacgac caccgcaaac atattggatg gtaccagata tccataacgg
    33841 caagtatcat cgctaggacg gaaaccagac catgtcattc ctgtaaaagc tgtttttgca
    33901 cctcgcccgt cattgatcag cgtatcttct tttcttgtcg tgtctcgtac aaatgtataa
    33961 ggagagtgtt catgatcttg ctctgttttg aacacgtcca agattttttt gataccttca
    34021 ataaaagatt gattgaattg atcagttttt cctgtatttt tgtaaagaag ataggccaac
    34081 tgtattgggt agcataaaga atcaatttca tattttcttt cccagatcca atcgttcatt
    34141 tttgtatgat ctgtttggtg gccagcaccg ttagcttctt cgttgaaggc attcgcatat
    34201 ggatcgatat tgatataaaa aaattgcttt ttgactaacc cgctgatcat gtcagctaat
    34261 tcctcatctt cttttgcaat cactaaataa ggacgaactt gtgcagtaga gtctcttaac
    34321 cacatcgctg gaatgtctcc cgtcaataaa aaggtggttc cgtcattttg ctttttgact
    34381 gttgtcaaca gagtattggc aaatgctgct gtaaaattct ttgcccagtc cgcatggata
    34441 tccccacatt tttgtgtgat atcttccata aatttctgca ccgattttgg tatatcttta
    34501 taagccacta ataaaacctt ctttctattt gatatatctt taaagattat acttcataca
    34561 gccaattatg tctacgcttt caaaaaatat ctttttattt actttttcat ccattatggt
    34621 attatttgaa tatgatatat cattaagagg tgtttatatg aatcaaccat tgtaccagac
    34681 aatatttaat gatttgcaaa cggctatttt aactggtgaa ttacctgtag acagccaact
    34741 accaactgaa aaagaacttt cacgtaccta taaagtaagc agaatcactt ccaaacgtgc
    34801 attgactgaa ttagagcaat taggacttat ttatcgcgtt cgcgggaaag gcagtttcgt
    34861 taaatccgct tctccggaac agattcttgc ttctcctaca aaaacacgac ggattctgtt
    34921 tcttcttcca tatgtcgctg atttgtctgt tggtgatttt agcaagggat tgaaccctgt
    34981 gatgcaagat aaacagattg atgtcatgat gacgacgctt gactttctac aaaataaaac
    35041 agcaaaagag ctaatcaatg aatttgacgg attgatttat tatgctcttg atacagaaca
    35101 acatcttgac ttactttttg agctttcatt gaaagaattc cctgtcgtca tattagataa
    35161 aaaaatctat gagttacctt ttcctaccgt tctttccgat aatttccaag gcggtgcgct
    35221 tgctgcctct tatttgatcg aacagggaca ttcaaaaatc gcttatttgt ttggtacgca
    35281 gactcatcca caatccgttc gacagcgtta ccttggttac cttgaagcat tggacaaagc
    35341 tggtttgact ttccacactt cactggatga caaaagcgcg acattagatg aattgctttc
    35401 ttatatcact aagtatgaag taactgcttt tgtttgtgaa aacgatgttg tcgctatcca
    35461 gaccatgaat ctcttgagac agcatggtta tcatatccct gaagattttt caattatcgg
    35521 atttgatgat atccaagcag cagctcttgt tgacccgcca ctgacaacca tcgcacaaga
    35581 ttttgaacag ttaggtaagc ttgcgggaga tgctttggtc acttggttag agacaaaaga
    35641 tcgaccatcc gatagtaaat ttccagtttc attcatcaaa agacaatcaa caaaggagaa
    35701 ataaaatgaa tatcggtcaa atagatacta gacatgcaac agcgaatcag ccaaatttct
    35761 ctaatgggaa ctgccagcct tatactggcg ttccttttgg gatgaattat tttgcaccgc
    35821 aaactacgga tcaaaacggc agctggtggt ttcatcctga tgaccgcgtt tttcaaggct
    35881 accgtcttac ccatcaacca agtccttgga tgggtgattt cagtcatatg ctgtttacgc
    35941 cgatcaatgg aaaactacag gagaacaccc ttttccatgc tcaaagttct taccgcccag
    36001 aagaaagtat attttgcccg actcatctgt cgatctgtca attacgttat ggcatctgtt
    36061 ctacattgat acctagcatg tatggcggaa tcttatctat tgattacagc aaaaatgaca
    36121 gcggtttact tttatccttt ccgggacgcc atcagctctt tgttatagat ccttacacag
    36181 tggaaggaaa aatcacacat tttgctggtt cagaagatcc tgatttttct ttttatttta
    36241 tattgagatt tgaatatcct ttaacaattg atgagttagc tgtttccaac aaaaatagcg
    36301 actcgatccc gttgtatttt gaacagacaa aaaaacaaac tatccgattt gggacatctt
    36361 ttatcagctc ggaacaagca gcttataacc tggaactaga acaaaaccaa agcaaagaga
    36421 cttaccttgc tcacagtcaa gaacaatggc agtcctattt tgatcgtata cagctcacac
    36481 accatgatca acaacaattg cggacgtttt atcataattt atatcgggtg tttttatttc
    36541 cacaaacatt ttatgaaatt gatcctagtg ggcaaaaaat ccactatgat acgactagtc
    36601 gatctataaa acctggtgtt ctctatacaa ataatgggtt ttgggatacg tataaaacgg
    36661 tttatcctct ttattctttg attgctgtag aaaaatacga agaaatgctg gaaggttttt
    36721 tgaacagcta tagagaaagt ggctatttgc caaaatggct gtctcctgat gaacgtggac
    36781 ttatgcctgg gacattgatc gatgcggtca ttgcagatgc tgctgtaaaa gatatccgac
    36841 gagacttgat gcctgaattt ctaacggcaa tggaaaaagg tgctacggtt caaagcaaac
    36901 atccaaatta tggacgccaa ggaacagaag attacttgac atatggctat gttcctaatc
    36961 actaccacga atcagtcaat cacacattag actatgctta tagcgatttt tgtattagcc
    37021 aagttgccaa ggtactagaa gaagaggaaa tgacgaagaa atatcagcag caatcattga
    37081 actatcaaaa tatctttgac tatgagtcag gatttatgcg ttcaaaagat aaagatggca
    37141 agttcagaga accattttca gctaatcgtt ggggacaaga ttatgcagaa ggaagtgctt
    37201 ggcaaagcag ctttgctgtt tatcacgatt tttcaggact gatcggaaaa tatggtggca
    37261 gtgagagata taaagaaaaa ctcattgagc tgtgcaatca gcccccaacg tttgacccag
    37321 gaggatatgg ttttgagatc cacgaaatga gtgagatggc cgcgatagaa tttggacaat
    37381 tagctatttc aaaccagcca agttttcact atccttactt gttcagttat ataggacaac
    37441 ctgaaatggc acagccactg cttaaacagt tgatgactca gaccttcgac gattctccaa
    37501 tgggttaccc tggagatgag gacaatggaa gtatggccgc ttggtatatc ttcaatagtc
    37561 tgggatttta tcctgtcacg cctggaaccg gtgaatatgt tatcggtatg ccattaattg
    37621 acaaggctgt tttgcttttg tcaaatggaa aggaattgac gattgaagca acgcctaatc
    37681 ggccgcagca acaatttatc cataaaatca aacggatgga caaagaatat acgaaattat
    37741 attttaccca tcaagatttg ctgaaaggcg gcacgatctc ttaccaatta gggatcatcc
    37801 ctcaccctaa gaaatatcaa gcaaaagatt tgcctttttc cttatcaaac tataattaac
    37861 aagaggttgt gaaaaagctg tcctgcatca agtaataaga acagccaagc aaaaatagat
    37921 cctcatattt ttcgtttggt tggtcttatt accgcagatg caagcttttg aacaccgttt
    37981 attgagaggt tgtgaaatca gcgttctgac ctgagtatta gagagacaaa tggcaaaata
    38041 gttcctcata ttttgccatt ttttgagcta ataccgaggg tcagctgatt gaacaccgtt
    38101 tagtggagag gtcgtgaaaa agctgtttag tttcgagtat taagaaaaat tttgtgaaaa
    38161 tggctttcca catttttgca taaatttggc ttaataccga gaaactggct tttgaactcc
    38221 gtttatcgag aggtcatgaa aaagctgcct tgcctcaagt aataagaaca gcccaaaatt
    38281 agatttctag acaatttttt ataagttatt tcattacatt ggctttttct tttatgattc
    38341 tccactgttt tctcggtact ctttagggga tctgccgacg attttcttga ataatttaga
    38401 gaaatacgtg gtgttgttgt agccaatctc acttgctatc tcattgatgt tttgattact
    38461 gtgcaaaagc agttgtttcg ctttttccat acgtaaatgg ttcaaataag ctgaaaaact
    38521 ttttttcgtt tcttttttga acagctgtcc tagatacatg acatttaaat gcaggttttc
    38581 tgacacttct ttgagtgtaa gtggttcttg ataatgctgg tgcaggatta cgattacttt
    38641 ttccacattg tcactgtact ttttctgtct ctgatgcttt ttgatgaatg acagaagtag
    38701 ctgctgaagt tcttgcaccg tttttgcctg atggattttt tcgattcctt gtaaatattc
    38761 ctcatcttcc agatcaatca attcccgttg aatctccata aacagtaaaa aactggaata
    38821 tcgtatatct tccggcatca tggctgctaa ctgaaactgt tcaaaaaaat cagtgatcat
    38881 tttttgagcg acttccaatt gtttattttg cagcacgcgt ctgaaacttg aaaaatcgat
    38941 ggtttgatct tttgtttctg cttgtactgc gtaaaaaaca tgctcgtctt tatctccata
    39001 aaattgatgc aactgtagat tgtctttcgc ttgttggaat gtttcaggga ttttgtccaa
    39061 agaatctgtc tcttccccga tactgatcag ccattcctga tcaggaaagt tttcttgaac
    39121 aaaacaacag aagccatcaa cttcatctgc ctccaacaac aacgtgatca atacacggtc
    39181 tccgtaattt cgttgatagt aaaagatttg ttgccgttct tgcaaccatc tattgataag
    39241 agtatcatga gttcttgcca gttgaatcaa tactatccta tgctgcttct cacttatttg
    39301 tcctattatt tcttcttcac ttatttcatc caattcttca ttcaaccatt gactgaataa
    39361 cagttcttga tagatttctt gttgattttt ttgttcattt tgctgatcta accgtgtttt
    39421 gattttcttg aggctttcaa ccaattcgaa cttattcacg ggtttcatca aataattcac
    39481 ggcgcctaat tgcatacctc ctttcaaata atcgaattct tggtatcctg ataaaatcat
    39541 aaattcaaaa ttatgacgtt ctttttgagc cgcttcaata aattccagtc catttatttc
    39601 tggcattgtc acatccgtta ctactaaatc aatctgtcgc tgttcaagta cagctagtcc
    39661 ttctttggca ttctctgctg ttgctactat ttgaaagcct aaactttgcc aatcaattat
    39721 cttttttaac ccattcaaaa tcatgtattc atcatctacc aataacactt gatacacgct
    39781 catccctcct tgaatgtaat agaaacggtc agtccacctg tctcattatt ctcaagcgac
    39841 atataataac tgctgccgaa gctggcacgt aaacgttcat tcacgttttg cagaccgata
    39901 gaaccgtgaa gttccacttt aggatgagac agtttttctt caatctgttt tagccgtttt
    39961 tcagtcatcc cttttccatt atctttgatg atgatcctta cccgtttgcc ttcctgcaag
    40021 actttgacac ttagcgcatt atcgaatcga gtaaaatcaa taccgtgttt aaaataattt
    40081 tcaactaatg gctggatcac aaatttaggt acttcgatct tttccaaatc aggatcgatc
    40141 ataaaatgat aggctactcg attaggataa cgcatttgat acaaatagac atatttttcg
    40201 caaaagtcca gttcttcttt taaagtgatc gttttctctt gattcgtatt gtttcgaagc
    40261 aaagcggaaa acgcatacac aacatctgct aattcttcac ttccttcgct gattgcatac
    40321 attcggatat attctaatgt attatataaa aagtgtggat tgatctgtgc ttgaagcgcc
    40381 cgcatatgtg cgtcttgctg tttgatttct aatttgtaga tgtcttctac aaactgattg
    40441 atgctatcca acatttcgtt gataccgatt gaaagttcct tcagttcata ttccgtgttt
    40501 gttatgtcga tccgcgtctc taaattccct gctgctgttt gatccatggc ctgcatgacg
    40561 atagatactt gctgtgaata tcgtttgaat gttttataaa gaaagataag cagtatattg
    40621 tctaaaataa tgataccaat gatcagcggg gcaagatttt ttcccgtttc gatttttaca
    40681 ctttttttat ctagtacagc taatatacga taatcatcag acagttcttg gtgttgaaca
    40741 aaattgtttt tttccagatc gtcaatcggc aattgtgaat ttttcttcag actctctgtg
    40801 atgatcattt cttgtctttc aaacgtttct ttagctattt tattatcatg gaatgtgtat
    40861 agtcgatttg tcgttccaga aatcatgtat aaagagagtc cattgaatga cgttagattt
    40921 tctaaaatca tatctagttc tttcttttga aaaccaataa aaatacttcc tgactcagct
    40981 cctccttgtg tgataggcaa cttgatataa aaggcgtcta gtaattttgg tgtccccttt
    41041 tttatttccc cacctttgtt ttctctagaa gattcataat actccggtag ttgattcaac
    41101 acgatatata tcgcacttag ttcttcataa tttgcgtaga gatctttgat ttgatttggg
    41161 aaagaaacta attcatcggt actgttttgc tgttcgtata catacatcag atactgatct
    41221 atgggttttg ttaagtaggt cgtcacattt tcgatctttt cggaattccc tacaagctgg
    41281 tttttgatga tcctactcaa ggttgtttta tcattcagca ttctgcttgt gctttgaacg
    41341 gcatcacttg tcatgttttc tgcctgtttt tgattttgtt cccaagtatg gatactaaaa
    41401 ataacggtag cagtcatcgt tacaccgatc atgataaccg cgtatttccg caacagacga
    41461 tttagtaagg ttccttttga aaatagaatc cgaaacttat tcataacttt ccaactgttt
    41521 atctaattct tcacgccaat gtgttgtcat cgtaccattc caaaccgtca aaagaccaat
    41581 gacaccaaac aggatcaatc ctttgaattg ccaagtcacg cctaaaatta taccgctacc
    41641 aataattatt tttagaaaag acgaaaagct ggaaaaaacc gaaataaaac ttagctttag
    41701 cagattagga acagagatcg tatattcact atctaaaatc atactgtatt gataagtagc
    41761 aaataggcag agcaaggcaa aaagtaaaat aaaatcaata gctaaaaaaa tgagcccttt
    41821 gatttgaaca gataaatata aattgtaact caataaagca gtaccagata aaaataaact
    41881 aaatagcaga ttgcctctta aaaaatttct tttatatata ttccagcctc tttttattgt
    41941 gatttcttta tactcgaatc cgtacaaata aaatagttca ttgactgttt tccatgccgc
    42001 acctaatcca aagatgatcc cgccggcaaa tgtatatatc cagaaataca aggttagttt
    42061 tataatgacc cagatccgga taaataactc ttccaaaacc ttccctaaca tatcttctcc
    42121 tccaaacatt aagtttatac tttctcatta tacaaaaaaa ggttgggcaa tcagcacctt
    42181 gacctgatta ttagagaaac aaacggaaaa atagttcctc atattttgtc gttttgtgag
    42241 cgaataccga gggttagctg attgaacacc gtttaccaag agtttgtgaa atagccgctt
    42301 agtttcgagt agtaagaaaa attttgtgaa tatggctttc cacattttta catatattta
    42361 gcttaatacc gagaaactgg cttttgaaca ccgtttattc ggaacaagag gttgtgacac
    42421 gtcttttgtc acaacccctt tgtctttatt cattattatt cttgtcggaa ctcatcatat
    42481 tgtttttgca tttctttcaa taccttatca tagccagcct tgtccaaagc gtctttcaat
    42541 ttcggtaatg tttcatctgg atcaacagtc cctgtattca atccatctaa atattgattc
    42601 atgacattag aaatattact taattctgtt ttgacactgt cagtgttgaa gctgaatcct
    42661 aaaatcggtg aagtttctgc atcagcaatc gattgatcac gtttggcaat catgtcatcc
    42721 gtaatagact cttgtgtata tagaatcttg ttgtttcctg tattccaagc agacatatgt
    42781 gtatttggct gataaccatc tagcaatttg attttatcat ctgaaccatc gactttttcc
    42841 catgcttctc cctcgatccc ccaaacaagc ccattcaata attctggatc actgttaagc
    42901 agccctagaa gttctactga tttttcttta ttttttgaag tatttgatac gacaaaattt
    42961 gccatttgtg cttgagctgt agattttagt ggaacagtaa ttgcttttga gacaagttct
    43021 tgttttgctg catttgtcaa aattgtatcg ccataatcat acggtccttg tgtttctcca
    43081 cgcattagcc aagtatttcc ttctagtgga taatccttat tgctcgttgc agcgtcactt
    43141 ggaatgagtc cttgtttgta ccagctatgc attgtacgta acagtccgat atacgtttca
    43201 ttatcgtatt ggttgatgat tttcgaatca tctccatcca gatcaatagc aaatggtaac
    43261 gtattcccta aaggataatc aaagttccct tggactttga agccttgtcc aatggcaaaa
    43321 gctgccgtgt ttggttcttt ttcatggaat tccttcaaga ctttttctgc atcagcgtaa
    43381 gattggattc catcaattga aagatcgtat ttatctagta aagctttgtt aaaagtaagt
    43441 acttgttgag caaagacatt tccattgact gggaaagcat ataattttcc attgaccaga
    43501 tttcctttaa tatatgcttc atctaaatca ttataagctt tttcagcgta cttaggcgct
    43561 aattcagtca aatcagcaaa ggctcctttt tgggcattgg aaacatagtt gttcgcaaag
    43621 gcgatatcat aattttcccc ggaagaaatg atgacgttca ttttcttttc gtaatcgccc
    43681 cagccaatgt aattgatatt gacttttaca ccgatctctt tttcgattcg tttgtttgct
    43741 acttccatca attgatcgaa attatctggt ttatctccga tttgatacat ctgcaaagtg
    43801 tccgaattgc tagcttctgc ctggtcttta gaaccagaac ctccgcatgc tgctaatgtt
    43861 cccaacaaca acgctgaaac acctgtaaag gctagtttct tccataactt catttttctt
    43921 cctcctaatt ttatgattta tatttttgtt tctttattct tttactccgc cgattgttag
    43981 acctttgaca aaatgcttct ggaaaaatgg atagctgatc gcaataggca acgtcgagat
    44041 gactacgatc gccattctgg cagattctcc tggaactgag gctaatccgc ctgtcaattg
    44101 gcttcctgct cctgaatttt gtgtcagata ttgaatatta ctttggattt tcatcaaaag
    44161 atactgtagt ggaactagct tatcatcttg gatgtatagt aaagcattga accagtcatt
    44221 ccagtaaccc aatgcggcaa ataaactgat tgtcgcaata cctggaacag ctaacggtaa
    44281 aacgatctga acaaatattc gcagttcgct agctccatcg atccgtgccg attcaataat
    44341 cgaatcagag accgaacgtt taaagaatgt gcgcatcaca ataatattga agggactgac
    44401 agccattggc aagatcaatg cccaaatcgt atcttttaac tgaagaagat ttgtcataac
    44461 aagataattg gccaccatcc ctggtgagaa caacatcgta atcaaacaaa aaacggtaaa
    44521 aaaacgacgg aatggaaagt ttgaccgtga aatcgcataa gcatataaag aagtagccgt
    44581 gctattgatc agtgtaccta aaacagtaac aagtacagtg acgaaaagcg cttggaaaat
    44641 tttatcctgc atctggtcga acaagtacgt ataaccaaat atactgaact tttctggcca
    44701 aaaactgtac ccgtgagtcg acaatatgga ctcatcggta aaagagatgg cgataacaaa
    44761 tataaatggc aaaatacagg aaatagcaaa gagtgcaatc attatattag agaaaaaatt
    44821 agccgtctta ttgaaagagc ggacttggac tctctccact ttcttttttt tcattttttt
    44881 cctccttaga ataatgcaga atcgctatca aaacgtcggg cgatcgtatt tgtgatcatc
    44941 aacaagacaa agccgacaac tgattggtaa agtcctgcag cagccgtcat accaaaatct
    45001 cctgtggatg tcaggccatt gtagatatac gtatccaaaa cttgagtcac atcatataat
    45061 gcaccggaat tcctaggaat gttataaaac aggccaaaat cagctcggaa aatgtttcct
    45121 acggctaaaa tcgttaaaat cgtcattagt ggaataagtt gtggtatcgt cacatgtttg
    45181 atctgctgcc atttgctagc tccatcaacc atagcagctt cataataagt cggatcgatt
    45241 cccataacag atgcaaagta aataatgctg ttataaccaa tccctttcca tgtaccaatg
    45301 aacaccaaga taaacggcca atatttcggt tcattatacc aattgacagc ttctcctcca
    45361 tgtccagtga tccactgatt gaatattcct ttgtcaggac ttaaaaaagc gtaaacaaag
    45421 taactgataa tgacccaaga tagaaaataa ggtagtaagg acatcgtttg ataaacttta
    45481 acgagtcgtt tatttctcaa ctcgctcata atgattgcaa atacgactga gatcagcaga
    45541 ttcaaaagga taaatgctac attatataaa attgtatttt tagtgatgag aaatgcttga
    45601 tccgaagaaa ataaaaattt gaaattttcc caacccaccc aaggactttc cctcaagcta
    45661 gccaagaacc catctgctga aatatgaaaa tttttgaatg ctacgacatt cgccattaca
    45721 ggtatgtaaa agaaaaaaat catccaaagc atacccggta cagccatcag gacaagtgct
    45781 ttataacgcc atagattcat aaaaaaatga ttgaacccct ttcgtttttt catctaaaaa
    45841 cccctttcga ttcattcgca acgtaattat agcgctttca ataatgagaa taaataaaca
    45901 aagtataggg aaaatgaaac aaagtatagg agaggttgtg aaatcagcgt tttggcctga
    45961 gtattagaga aaaaaacggg aaaatagttc ctcatatttt gccgtttttt gagctaatac
    46021 cgagggtcag ctgattgaac accgtttatc agaggttgtg aattcagcgt tttggcctga
    46081 gtattaggga gatcgtgtcc ttactatcta actctgagtc acaaggaaca atggggactg
    46141 taacaaaagt cttgtcacag tcccttattc cgaacaaacg gtgttccaga agtagcttct
    46201 acggaaataa gccgaaattt cacaaaaaag ccatccgaaa gtcagacgga caagtctgct
    46261 tttcagatgg cgctacaact actctgctta ttcttttagc tatccattca attatttttc
    46321 tctcacttgt tctagctctt ctttggtcat gggtcgatat tgccctttat tcaaatcttt
    46381 aggcagccaa aattttccca tacggattct ttttaaatat aagacttctt ttcctactgc
    46441 tttgaccatt cgcttaactt ggtgaaactt tccttcatgc aaaatcagac ggataattga
    46501 agtttctgtc tcttgatcta cttgatcaat ttggagtttt gccggcaatg tctgctcatc
    46561 gccatcaata atcagtcctt ctgcaaataa acggatatct tcttctgtca ttataccgct
    46621 aacctcagct agatattctt tctccacatg ttttttaggt gatagtaact gatgggcaaa
    46681 caccccgtca ttcgttaaaa tcaagaggcc ctctgtgtct ttatctaatc ggccgactgg
    46741 aaaaagatct tcccgataat cctggtcttc caataaatcg attacggttt gatcatgatt
    46801 atcctgagta gcagaaatga ctcctgcagg tttatgcaaa atgtagtaaa aatctttttg
    46861 atacgtaatg atttctccta aataagtaac cgcatcttcg aattcattta cttgcgcttt
    46921 atcgcttttc accacttgtc cattgacttc gatcgttcct tttttgatta atcctttgac
    46981 ttctttgcgg ctgccaagtc ccatatctgc taaaaactta tctaaacgca tgcgtttccc
    47041 ccatttcaaa agagcatcaa tctagctctt ctgattcact tattttattt ttaatttatg
    47101 tcgtaaacgc gctattcctg gtcctagtag tctttctgcc aagcggattt tcaaagctaa
    47161 ataaccatac actaaagccc ctatacctgc tactacaaga atcaacaata gagactggaa
    47221 tttgctatct tcgtttaaaa aagcaccaaa aatcatcttt gtgatccacg aagccaaaag
    47281 cataatcaag gtaagaataa agatcagcaa tgtcctgcgc cagacaaaac ttggtttaaa
    47341 gcgggctact tcatggattc tctttaagat caaggtacaa gacacagcaa atccgatcat
    47401 tgtcgccaat aaagggccgt atacttcaaa taaacgaatg gctgggtatt gaagaaggag
    47461 tttcactaga aacccaataa ccaaataatt aattgccgcc ttgttttcaa acattccttg
    47521 cagcatgttg gaaactagca tatatagtcc taggaagagt cctacaaaac ttgcttggat
    47581 cagtacatta cttcctagag aatccggtgt ataaaataat gtatttagcg gataggcaag
    47641 taacataaca ccaaatgtcg ccggaaacat aaaaaatgaa aacaactgta aatttccgct
    47701 tgtcaatttt gccagaccta ctcgatcttt caacgtaaca gcttctgtaa tcaacggtaa
    47761 cccagtagac gcgatcgatg ttgccaatgc aataactacc atcgtcaact tatctggatt
    47821 ggcactaaaa atcgaaaaaa gatccagtaa ctgtgcattg gaatactcgg tggatgcaga
    47881 catgatcttc ataaaagtga actgatcgac taatttgaag atcgttaccc ctgaacccac
    47941 aataataaac ggaatcgctt ctttaacggt atctaacaac aattccttcg ttgcaatatt
    48001 tattttgttt tcgctgtagt gaataaacgc cgatgtatac gcttgatgtt tcttcaaaaa
    48061 atacaaaagg acaagaatac ttgctagcat accgataaat gccgcgaaag ttgattgcgt
    48121 gaccgccgtc acatagtcac catccatgac tttcatgatg atgaatgtag ccaatagcat
    48181 ataaaaaata cgtgccacct gttctacaat ctgcgacagc gcataaggca tcatttcttg
    48241 attgccttgc aaataccctc gtatcacact catacaagga aaaaccaata cagcgatact
    48301 caaagaacgc atcgttggaa tcagttcttc tccgccacca gaagcatgag ctagccaagg
    48361 agaggcgatg tacatgaaca aagcaaacaa caggcctaac ccgcccatca tctgtaatgc
    48421 acggataaat aatcgtcgtg aagtgccata ttcattcaat gaattatagc gtgcagtttg
    48481 ttttgcaatc gcagcaggta ttcctgctgt agagatcagt agaaacaatg catatatatt
    48541 gtatcccata ttgaataatc cattggcagc cttagcattt tcgcccatcc aagcatacca
    48601 gggaatgata tagacagcgc ctagcaatct tgaaatgata ttactggcgg tcatccaagc
    48661 agagcctcgt gccatttttt cttgcggtgt taattgatct aatgctggtt ttctttgatt
    48721 atccatcggt cagattccaa ctttctacaa aacattacta tcattttaat tggtaaaaca
    48781 gaaactggca atcgatttta tataactttt ataagaacaa ttgttttttt gaattcggtt
    48841 tcgttttttt ggtaaagtaa agaaatatac agccttttat ggctaacatt tataggagat
    48901 atcaatgaca caagaaataa aaaaactacc cgttatattt ttaggtcttt tctttatcac
    48961 agttggattg aattggttct tgctccctca cgatatagct tccgccggag tgggcgccat
    49021 cggacattta gttgaaacgg ccttttctat ccaacgctca gttactgttt ggagcatcaa
    49081 tcttatgatg ctgcttctag ccgctgtcct attaggaaaa tcagtatttt ttaagactgt
    49141 agcgggaagt ctgctttttc ctgttgtttt agagattgtt ccaaaagtgg aaatgatctc
    49201 ctcacatttc ttttcactga tttcaggaag tcttttgttc agtcttgggg tttacacatt
    49261 gtacacagtc ggggcctcaa atggcggtat aacgataccg ccgattattt tccacaaatt
    49321 ttttcggctt ccaatgccgc aaggactttt acttaccaat agtcttatcg tctttttgaa
    49381 ttattatgtt tttggattgt tggagacact attcgttctc ctatctatta cagtcagttc
    49441 attgtttatg aaaatactca tccgcttgtc ccctgtgtca agaaaatttg aataaagctg
    49501 gattttgtca tagcggaaac aaacgatata ttaaaaagag tgtgctataa taaaccaaga
    49561 aattgaataa agcgagggat caatcaatga gcttctcttt agaagacatc cgtcatttac
    49621 tattaaaaga aaatctatta aaagaatttg tttcaacaag aggctggcat cttgatgtac
    49681 cagaaaaagc tgaatttctt cagttaagtt atgattcaag aaaagctgat gcttctactt
    49741 tgtttttctg taaaggaatg aatttcaaag aagaatattt ggattcagca atcgaacagg
    49801 gtattcaata ttatgtatca gaacaaccat acgaaaattc agcagtagga atcatcgtaa
    49861 cggatatccg taaagcaatg gcgcttcttg ctatggcttt ttacgactat ccgcaaaata
    49921 aattgaaagt gatcggattc actggaacaa aaggtaaaac aactgctgcg tactttacaa
    49981 aagcaatctt ggatcacaca acaaataaaa aaacagcatt gctttctact atgaatacaa
    50041 cgttagatgg caaaacatat ttcaaatccc atttgacaac gcctgagtca ttagatttat
    50101 atcgtatgat gtcagaagca gttgaaaatg gtatgactca tctagtgatg gaagtttctt
    50161 cacaagctta caaaacacaa cgcgtatacg gcttgacttt agatgtcgga atcttcttga
    50221 atatctcgcc tgaccatatc agtccgatcg aacatccgac atttgatgac tatttctatt
    50281 gcaagcgaca attgatcttg aattcaaaaa cagttgtttt aaatcatgaa agtgactatt
    50341 ttgatttact tagggaaaca gccgatctat tccagattcc aacgatcact tatggtcgtt
    50401 cggaagaaag caattatcaa gtgatccgtt cagataaagg tactcacggt tttactttat
    50461 cttctcatga agatcgctta gctatctgcg atactgctta tgatattttg ctggctggag
    50521 gattcaacca agaaaatgca gccagtgcga tcattgccgc agcactaaca ggtgcctcca
    50581 gtcaagatgc acaagacgga ttaaaagaag ctcgtgtacc aggccgaatg gatcaattga
    50641 tccaatccaa tggagcgcat gtctatgtgg actatgcaca taattatcta agcttgaaaa
    50701 cattgctgaa atttgccaaa aatgaacatc cagatggccg tgtaattgtt gtattaggca
    50761 gcccaggaaa caaagcaatc tcccgtcgac atgattttgg aaaagtgcta tcagaaacag
    50821 ctgacatcgc ctttttgacg gcagatgacc cagcatttga agatccgaaa aaaatcgcgg
    50881 aagaaatcaa tgaagcaatt actaatccag atttgatcgt tcattatgaa atggatcgtc
    50941 ctgaagcgat tcgacgcgct ttagcagaaa gcgctccgca agattcagtc gttattgcgg
    51001 gaaaaggcgt ggatccctat caaaaaatca atggtgtaga tgaaccttat gaaggggatt
    51061 atgcaatcgt gaagcggttg attgaagaat aatggtattt atatactagt ggtttcccat
    51121 ttctaagaaa aaaagggact gtgatttttt gtcacagttc cttttttctt agaaatcatt
    51181 ttaacttttc actagctaat tctgctgcct tttctctttc ttcatttaat aatttattat
    51241 catagaattt gataaatggg aaccagataa tgaatgcgat gattgcacaa atgactgcta
    51301 acacagcagc tttccaatca ccaccactac caacaaatgc tccgatcccg actggtgaag
    51361 gccacggcat ctgtgcaagc atcggtttga cgatttccag ccgaatggca aaataagcga
    51421 gtgtagcaga agccatcgga gctaagaaaa acggaaccgc taaataggga ttgtagacga
    51481 ttggcatccc gaaaatgatt ggttcattga tattgaataa tcctggtaca agtgaggctt
    51541 ttcctaacac tttcagctga tcagatttcg cgaggaatgc aataaagatg atcaatccta
    51601 aagtcgcacc tgatccacca acggttacat aagaactgtt gaattctcct gccaacggat
    51661 aatttgcgcc ttgtgcgtta gctgccatat tagctaatac gatcggggtc aagaaagaag
    51721 tgatgatatt cgctccatgg atccctacga tccacaatgc atggatcaag aaataaatca
    51781 ccatgacacc aagccatgta ttcgtcaact gcgtaacaaa cccaaatggg atagcaatca
    51841 ttttgaagat atccgttcct agtgcaacta ataatccatt gatgatcatc accacaaacg
    51901 caatgacaaa tgttgggatc agagcagtga aagaacgaga aactcctggc ggaacaacat
    51961 ctggcatttt tatgacccaa tttctcttga cacacataca atacaattcg accgcaataa
    52021 tcgacataat aatagctgta aagattcctg aagttcctaa acgttcgaca aaagagccca
    52081 tcctaatacc atttactaca gtttctgtct cattgataga agcaatcaag ctgattttac
    52141 catcagtcat gatcaattca gggatacaca taaagaatgc aaaaacagat agtaatgccc
    52201 ccgtgagcgg attaacattt aatttttgtt catctcgttc aattgacgtt aattcataag
    52261 caaacacaat ggcaaagtaa atagataaaa tccccatcgt cattgtattg acgatcatgt
    52321 acaagtcact aactttgaaa aaagttgcat taaaaaatcc ttctaaaaat gggaacggta
    52381 atggcaaaat atttaaaacc aaaaacatcg agcctacaat cgtgaaagga atagaagcca
    52441 tccccgctgc catgacagcc cgaacgattt taagttgcgc aattttcccc ataggtccca
    52501 tcaggtattt ctgcaaaaaa tcaaacatta gttattctcc tttcctaaat ataacgcttt
    52561 ttcatattgt ttaatacgga tatactgttg gtcttggttg agtgaaattt tctttaaacg
    52621 atactgtata aatgcactgg caaaaatacc gcttacaaca agaatgaaaa caaataactg
    52681 tcctccattg ttatttgcca taaaaggata caagaatgta aatcctgagg taaacaacac
    52741 tggaatcact aataaattaa agacactctg gaacaaaaaa taccactttg tccatggaac
    52801 gttcgtttgg tgttttcgat aaagctttac ttgttctcct actgcaggca aaatagctaa
    52861 aatcagaatc atcggtaaac tacttcctaa acttttagct gatagaagca gaatcatcca
    52921 ttgcatgttc atgaaaaaga aaaaggcagt caggtaacgt acgattagat aacgattgaa
    52981 atacatgttt ttcaaactaa gttgcttttt ttctaattcg attttccttt ttactgtatc
    53041 ctgcacaatg atccttcctt tctatttatt tttttgatac aaataattca tttcctgtgc
    53101 aacttccaat aatgtcatcg tcgtcatcag atgatcttgt gcatggacca tgataatttc
    53161 catttctatt tttgtcccgc tggcatattc tttcagaagt tgagtttgtg actgatgcgc
    53221 atgaagaatc tcttcatttg cttgtcgcaa cttctcttct acttcttcaa acatctcttt
    53281 acgcatcgag cgaaatgctt catgtatcag tgtccgtgca tttccgctat ggaaaatgat
    53341 atcaaaagaa gtcacttgta gtgtttcact gtttattttt tcagccatct gttttcctcc
    53401 ttattcgatc agtttgataa atttactgct gaaattctca aaaataggtt cagctaagat
    53461 ttcctgctgt acttttagct ggtcaactaa cctaacgatt gctttagtca cgaccgtaat
    53521 tccttcattt tcgacataag aaggcgaaac taaaaaaaca aaatgaattt cttgatattg
    53581 atcccactgc atcccagaag gaatcaatgc aacggctacc tttgtttcga ttccaactgg
    53641 aacagcggga tgtgggactg ccactgtatc actgaatatg atttgtccca tattttcacg
    53701 ttgctggatc tgctttcgca tttctcttat atatccttct tcttcattta tgctcagctt
    53761 ttgcagcaaa tcatgaagaa tttcttcctt tttcggttcg tacgtataag tcttgaaaaa
    53821 tttttcagac aactgttcgg tgtaaatctg ctttttttgc tgtagagaaa atgctggtat
    53881 cggtctatct gaggaatgat agggtataga ttctccaact acctttcgta ttttacgaac
    53941 atcatcttca ttcaaaaaaa tactgacatg taaaactgga attttgaaaa acattgtcga
    54001 aagatcaata gaagaaataa tcaggtcgat tccttttaaa gttgtttcat tgatctcata
    54061 atagcctttt acacttacca ctgtaatatt tttaccgaat tcactgacta cgcgattctt
    54121 taatagttgg gcactgccgt aacccgttgc acagataatc aatgcatgta gtttatgcgc
    54181 agctctttct ttttccaatg ccgccatgag atgcaaagcc aaataggccc attcatcttc
    54241 attgatggta tagtttttca aagccggcat gttgctgaaa tgccttttta ctgcgtcaaa
    54301 gactttggga ttttctttct ttatctcctc agtcaatggg ttctcaatgc gaatacctcg
    54361 gctcaatcga atcatcatcg gtgacaaatg atcgagtagt ccattgaaaa gctggagatc
    54421 ctctactaat gaaaaatgaa attcctgaga caatcttttc agaactttcg ctaattcctt
    54481 tgatagttcc tgatcatttt gattttcttt gtgattcgac ttagccatga gatgtaatgt
    54541 caaataagca atttcttctt cgggaaacga tacacctgcg attacctcaa tacgttgaac
    54601 gatccgctgc gccacttgat actctactcg cttagaaact tcttgttcga tgcctaattc
    54661 cttgatttca aacccttctc ggagccgttt gatccccaaa gccaagtgta aagtcagatt
    54721 ctgtatgata aaatccgaaa cttttaactt agcttctctt gtttcatcga gaatgataat
    54781 gactagctct tcaaaactga tgtctgggaa aaaacggctt tgccctaaat attctttcaa
    54841 tgaatttcca taatggtttc caaaaaaagt atccatgata aaatgccgtc gatttctttc
    54901 ttccccttcg atccatgtcc cttgaccatg cttagaaacg atttttagtg aatatggaat
    54961 caatcgctcc ttgatttctt gcatgtcctt tgtcaaactg gaacgactga tataaagctc
    55021 ttctgccaaa tcatccataa aaagaatggc atcttccaaa agcaattggt tcaatatata
    55081 cttttgtcga tcttcggact cataaaatcc ttgcggttct ctagcatatc caggtactat
    55141 ttcttgccga ctcaaaaaca agtcaaatgt cagtctttgt aaaatatgca gttggtagcc
    55201 ataacctggt ttagcaatga tcttacctcc gtttttttct actaactctt tgatccgctg
    55261 caagtaatta cggattgtcc gatcagataa taacaattca gaagctaaac gttgactggt
    55321 gacatactcc ttcttgtgat caatcaaata tctcaacagc aatttttcct tctgtttcat
    55381 tatcatccac tcctattcca tcatatgttc tcttcgatca cctctgctaa cttctggatg
    55441 cctgtaggga ttgggacata cgcttggaaa gggatactaa caacaggctt tccaacagat
    55501 tctcctaatt ttttgaattt atccaaaaac atcgtcgttt gcgggctgat cagaaataaa
    55561 tcaaaatcac tattcttaat catattatcg ccttctgtag ctgaaactgc atctacgagt
    55621 acctcttctc ttttttgctt aaagaaatcc gttgtctttg aggccatcat cgaggatgac
    55681 attcctgccg cacaaataat caatgctttt ttcataaatc aatcactcct tttattttta
    55741 taaaccaagc atatcttgta agcgttttct attcaaaata tatatttccg tagcattgcg
    55801 gaaaaaatgt gtatcatatc ttgaataata atttctggca ccgtgatata ctagtgatag
    55861 aattttttca ggaggggatt tagtgagtat cacagtgaat attttgtata caagtacaaa
    55921 tggacaagcc agaaaatttg cagaagaaat ggtcgaaaga aacattgtca aagcgattcg
    55981 tgcagaagaa ggaaacgaga aatatgacta ttactttcca ctagaagatc cagaatctct
    56041 tttactgatc gaccgttgga aagatgaaga agcaatcgaa aagcatcaca aatccgaaat
    56101 gatggctcaa ataaacgaac tccgtaaaaa gtataaatta aaaatgaaag tcgaacgttt
    56161 cactgattta ccgtaaaaag atacacatgg aatgatagca atttatcatc catgtgtatc
    56221 ttcacttttt ccttattttt tattcgatct catctaatga ttcaaaccgt gtttttctct
    56281 tatttttcgg ataagtattt cagtcacccc aatatacatg attcctaaac ataccccaag
    56341 gatattctca aaaatgcgga tcgttactgc tcctggaacc ccgaataaac tggcagtgat
    56401 tgccaaagca ccaaaagaat taaaaactgt tttatatcta taggtagaac aaacacctaa
    56461 agctagacca cctaatatac cgacccagtt aaaaggaata aattggctga taccaataaa
    56521 taaaacacat ccaatcaatg agccaatgat tcggtctact gctcgttctt tgaaaccaat
    56581 cgacatcaat ccatagctag atacaataga agaaaatgca aaccctgccc acatcaatcg
    56641 ctgaaaaggg acatactctc ctgcaacgat caaaagacta atgccaaatg catagatgag
    56701 catccaaatt ttttcctgcg aatacatgcc tttcaaaaaa atctctttaa acaagctttt
    56761 gtctttgttc ttttctcgat gttttctgta aaggagaact gaaaaccaac aaaaaaacaa
    56821 aaataataag ctacttgttt gtgtaaagaa attcttgttc aacgaatctt taggtaacga
    56881 ataaacaata aagagatatg aaaagccgta caaagaagca ttccccattt tgggatcact
    56941 agcggttgcc attaatatgc tgcttagtaa aataaaatga atcaacatgc ccataactga
    57001 ccatttgatc agctggacat acggtgctac taatagtgag aacatgacga ttgctaaacc
    57061 tatgatcgaa tgggaaatct tataaccaaa gtcaacaaaa cgaatactca tcaacataca
    57121 gaataaaacc acagcgtatg gtttatgctt cgattcaaat aatgttgtaa ttataatgat
    57181 aaaacaaatg gcaaacaata cgatgaataa tgatcgtaaa aacaatgaac aaatatacat
    57241 gcacttttct tttttagaag ctgcttctcg tattttttgt tttaaaataa acggatctag
    57301 ttgtagagac tgataaaaat ccacctgttg tcgtcctttc tttttacttt tattttttac
    57361 agtcatctat gacaggttgt aaatactatg gaacatcata tggcgttgtc attttcttgt
    57421 caactatttt tcctattcat gtttttataa aaaaacatat cgttttcttg tatgattaaa
    57481 tcaccacaaa ataaacaact gagagaacga tatgctttat gaatggttct atcaaaaaaa
    57541 ttctgagatc aatagacaaa aatttgatga ttacagaggt ctcttacgaa accttacaga
    57601 agaaaaaaac attgatcgtt gctgcagttc tcttccctgc tccatgtgtc tgtagaaatt
    57661 gtggttctgc tgtggtagat ggaaatagga aattaatggt ggtgaaaaac aagaagaagg
    57721 aaaccattgt ccactttgaa taatataatc atatgccaat ggttatacgc ctaaaaaagc
    57781 agcgctatac ctgtaaaaac tgtcgaagcc attggaacgc tcaaagttat tttatccgtc
    57841 caaggcactc gatttcaaat catgtcagac ataaaatcac ttctttactg actgaaaaag
    57901 tgtcgttatt ttttatttcg aaaagttgtt aggtatcttt gacaaccgtt attcgcacat
    57961 tgaaagagtt gagaagctat ttaccaaagt cttccaaaag aattctgtct tgagtgttga
    58021 gggttgtgaa tttcgttctc acgtttccgt tgaggataaa ctgagtttta tttccgcgga
    58081 tggcgagaca gaaaaattaa tcgagaaaat ttacctacac aaaaaattcc tcgattaaca
    58141 aactatttcc ttagctgcac taatcctaaa gaaatagaat tcttagttac agacatgaac
    58201 gccacctact ttcagctcac caaacatgtt ctaccaaatg cgaaattggt gattgatcga
    58261 ttacttggtt tttccacgcc tttcaaggag gcgtaacctt tattcacgag ttggttgaag
    58321 ctttccgaga caaaagaccc gacttgtttt tctccttatt gacaaagagc cattaaaact
    58381 agagaaaaaa ttacaactga tcgctgatta tttgtagaaa gaaaatcaaa gtattaccca
    58441 ataaacttga gtcattaggc aaaaaacact gcgaaactca agaatgattt tcgcagtgtt
    58501 tttgtatatt ttttattaac tagtattact acaaaggttt atttttcact tctcaacgca
    58561 gcacaaaatt gtctttactt atttactggt tgggttcaac cttctctact ccgatactaa
    58621 tatttgtttg tatacccctt ctaaaatcgg tagtttccat tcaattgatg ggtactagtt
    58681 gattttaaaa actatgctta ttcaattttt tattttagct catatatttc gtttctttct
    58741 aaattttata ctgatgaaaa caagtagcac acccaatatt gacaatataa actggctaat
    58801 gatggtttct ccagtttttg gaagatgctt atttccactg cttgttggat tgtttcctct
    58861 tatatctgag ctatcagcaa cttttctatt ctcttttgtt aaaaagatcg ccacttcttg
    58921 ttctttttcg atcttgaaag ttactggtgt cgcatccaat tcataccccg ttggcgcttg
    58981 agtttctacc agctgatatg ctcctggtgc taagccatct atcgccagtt ttccatctgc
    59041 tcctgtggtt agacctgact gcagaacggt tccattggca tcttgtaact caaaaacagc
    59101 tccttgcagg acttctccgc tttggtcatc gatctttgtc aacacgacac cgcctggtgt
    59161 aagtcgattt tctttcgtca attctaccac cgctgtctga cttctttcga tctcaaactc
    59221 gattggtgtc gcatccaatt cataccccgt tggcgcttgg gtttctacca gctgatacac
    59281 tcctggtgct aagccgtcaa tcgccagttt tccatctgct cctgtggtta gacctgactg
    59341 cagaacggtt ccattggcat cttgtaactc aaaaacagct ccttgcagga cttccccgct
    59401 ttggtcatcg atctttgtca acacgacacc gcctggtgta agtcggtttg ctttcgtcaa
    59461 ttctaccacc gctgtctgac ttctttcgat ctcaaactcg atcggtgtcg catctaattc
    59521 atacccc
//
LOCUS       DAFBVQ010000010        56387 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.010, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000010 DAFBVQ010000000
VERSION     DAFBVQ010000010.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 56387)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 56387)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..56387
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.010"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            330..1175
                     /locus_tag="LLC22_000793"
     CDS             330..1175
                     /locus_tag="LLC22_000793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5434090.1"
                     /translation="MDEMKLIGIDLDGTLLNSDQSISQKNARTMKHLPEDCFPFICSG
                     REVEDINNILKKSGLRIPAVGLNGSVGFDGEKKIFESSFDKNDVKKIDSVLSKFPTKI
                     YTNLGSYESQNYKNKMKKIFHEVGSEFSIKELNYELEYEKSICSIPYNNIEEIIEKDA
                     ISIYKFFIFIPNRQLKANIFNHLKKMLNVSVTESAPVNIEIVPQNVSKGVVFDRLESI
                     YNLKKPLRIAIGDSLNDLSMFESADISFAMGNSHQEIMKKADYVTVSNDKDGVSQAFE
                     RILTI"
     gene            1456..2676
                     /locus_tag="LLC22_000794"
     CDS             1456..2676
                     /locus_tag="LLC22_000794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair exonuclease"
                     /protein_id="HBK5434091.1"
                     /translation="MVKFIHAADLHMDRSFEGLTTLDKTVQEKLLKTNLTVLSNIIEQ
                     AIINNVDFVLLAGDNFHQNRPSLKIQKHFSEQMKRLEKNHIPVFIIFGNHDFYQKERY
                     WFSFPKNVHLFTSETVETKKITIKSGETVSLSGFSYRQPWIQKDKVMEFPSRELTDYH
                     IGLYHGEPGVSQKGNYAPFQPSKMQEKGYDYWALGHIHVPTVLNEKQTIVYPGAPQGH
                     TKKEQASTSILLVELSKGSCQIHPIKVAEVYWKTKEISLRKARTTKEVIVHIRQQLSK
                     VEDGFSLIEIKLKDYDHLNTDVLERIQSGELLDYLLEEFSDRINDFFIWRISLIENTF
                     YTKTPLAASAKLMEQLFQYYQTPQDFQQILNEVYSHQEAARILSELPEYQEETLEKAK
                     QLLNQDFLFEEDQE"
     gene            2673..5393
                     /locus_tag="LLC22_000795"
     CDS             2673..5393
                     /locus_tag="LLC22_000795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5434092.1"
                     /translation="MKILRIEIAAFGKWRQKSFDFYSGNQLIYGGNEAGKSTIYQFIQ
                     AILFGFPSKGRKKKDYTPKDGSAYGGKIWLKHPVYGEFAVERYKQQNRGKSKVWLGDQ
                     VGSDELLEKLIAPLTKELFQQVFTFQQEQLMELDHLREKELHDALISLGITGSSQVFQ
                     KRQEYYQKAQQLFKKKGQKLLINQKLNEWKELQEKIHQKQEQEAYFGKLIQQEQEYES
                     QQQQLLAQLKEANKQFSLARQQELNFSLYEEWQSLKKNSTTGLPDEQLLLDLESFSKR
                     YQQTNERLEELEATLEKHSGMDQQSARYYFYLEQEQELKDLQQLQFTAEQLNEEWQRL
                     QIETRETNSELKILEQRWHWQKNPLPEEFLYEEEWKHLLAEERRIADLESQISVRLQI
                     AKEQQEMIEAEVNDLEETYPALLQNQSEIAPVSSSKPYMLMAGGAIIIAGIFVPMPLK
                     VILLLIGAGMIGYFFYKRQPKIKTKNDFSEIKGMWQEKLGQLDLALAQLAEAEEKQKR
                     TGEEKQILQQEVYRFADHRHLGKMDTLKLMKEYGQEVIDYQKLYGVFERKHKREQEIQ
                     EKLRQIDQKFEFVKEWLPIQDKTISEKMVLLSRFIQEMEQMKFARSYQQNTLLKQEIN
                     QLKKKQKVWIQEYSEQLTQAGLSYPSEVPVFLQKAKQAEQQMKRYNELSEMLTPLFPE
                     ELTKEKLSVRLRQLKEKQSQLQQEEKEASENRQRLQLQVEELQRDGTLDELYQQASRQ
                     KAKLQELLEEWGALEIAGTFLGDLSTEMSERQLPQLLRAAGDYLGILTKGNYQKILLK
                     NDTLTLTDGYTEFPIYELSTGTKDQLIMAMRFAYLSLEANRSICPIIIDDGWLHYDHQ
                     RKYQLAELLAKFGEKYQIICFSSDKEMVSYYHEMNQIVKQLEGANNEKNS"
     gene            5377..6321
                     /locus_tag="LLC22_000796"
     CDS             5377..6321
                     /locus_tag="LLC22_000796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5434093.1"
                     /translation="MKKIRDLVIDEQFEQFVLIKSADVRIAKNGKKFIAFTFQDTSGT
                     IDGKYWDASEEEINKFTAGTVVFLNGKREVYQGNPQVKILHMRLTRVDEPGEPSLYME
                     RAPLKKEEMEEEINQLLFEITNAHWNRIVRYLLNKYQKQFFEFPAAKRNHHAFASGLA
                     YHTLTMLHLGKSIADEYPELNRALLYAGIILHDLGKVIELSGPMSTEYTLAGNLIGHL
                     VLIDEEITKACLALKISEADEDVLVLRHMVLAHHGLLEYGSPVRPRIMEAEILHQIDN
                     IDASMQMMLTSIRQTEPGKYTDRIFGMDNRSFYVPKDL"
     gene            complement(6390..7400)
                     /locus_tag="LLC22_000797"
     CDS             complement(6390..7400)
                     /locus_tag="LLC22_000797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5434094.1"
                     /translation="MKKKSIILAATSALAVLTLAACSGDTNKDIATMKGGTITVSDFY
                     DEAKLESSNQSLVQRMIIYKVFNNKYGDKVTDKQVDAEYDKQAKSLGDTFESQLEAAG
                     YTKDTYKEYIRNNLAFEAGLKAHVDITDDDLKTAWKSFHPEVEAQIIKLSSEDEAKDV
                     KKSADDGDDFSKLAKDKSTDTETKEDGGKVKFDSTTTTIPAEVKEAAFKLKDGEISDV
                     ITTTNPTSYATEYYVVKMVKNQNKGNDMDKYKDQLKDIATETKLSDNAFTTKVIGEEL
                     KDANVKIKDDAFENVLSAFTTTSSSTKDSSETTASTKSSDTKSTDSTKESSTEETTDS
                     SK"
     gene            complement(7580..7924)
                     /locus_tag="LLC22_000798"
     CDS             complement(7580..7924)
                     /locus_tag="LLC22_000798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK5434095.1"
                     /translation="MIKNFFKGLLFGAAAGTVGGLLLAPRSGNETRKKLIEELEEATT
                     LTNDLNNSLNHFKSALIETKETAESVIPAFQEAIKKDIEDFKFQAEPRITQINEQVEK
                     LKADLPEYPEQI"
     gene            complement(7917..8351)
                     /locus_tag="LLC22_000799"
     CDS             complement(7917..8351)
                     /locus_tag="LLC22_000799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HIT family protein"
                     /protein_id="HBK5434096.1"
                     /translation="MENCIFCKIINQEIPSYKIYEDDKVYAFLDISQATKGHTLVVPK
                     RHVADIFEYDPELAGEVFSRVPKIAQALEKAFPEMKGLNILNNNRELAYQSVFHSHIH
                     LVPRYSKEDDFSIHFVNHQDSYGSEELKAIQETIVKQVSCDD"
     gene            8489..9226
                     /locus_tag="LLC22_000800"
     CDS             8489..9226
                     /locus_tag="LLC22_000800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434097.1"
                     /translation="MSLIIDHVTGGYGHLPVLKDISFDVQPGEIVGLIGLNGAGKSTT
                     IKHIIGLLEASKGTIEINHLSLKKNTEEYRKQIGYIPETPSLYEELTLREHIEVTAMA
                     YDIPMDIAMKRAEKLLETFRLSNRLDWFPANFSKGMKQKVMILCAFLIEPSLYIIDEP
                     FLGLDPLAINALLELMVEMKKEGAGILMSTHILATAEKYCDRFVVLHNGEIRADGSLE
                     MLRKEFQLPDSSLDEIYIALTKEQAHE"
     gene            9219..10430
                     /locus_tag="LLC22_000801"
     CDS             9219..10430
                     /locus_tag="LLC22_000801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434098.1"
                     /translation="MSSFFQKRLARHQKKMMKYMRYVLNDHFVLVCLFLIGGVGLYYS
                     NWLKTLQPPFAIGGLIISVFWMLCLFVGKMATFAEAADIVFLLPKEKEMQTYLERAFR
                     YSCIFPLIFLILACGLAMPLVVVSTEQSFSMFFVYLIILWSLKFSHLQIKRAELFRLD
                     QQVIRYWKLGWFFSSLIFLFLSFYWLIWAGIAGALVQASLYYWFLWKQQEKGLDWEKM
                     VHVEEHRLHQIYQFINLFTDVPEITAKIKRRRYLDPILTHIKRESKNTYLYLFARRLA
                     RGSDFSGLYFRLVIIGGLLIAGVVDFYFSLIIGFLFLYLIGFQLLPLANQFRYMVLVQ
                     LYPIHKNQKKQAIQYLLTWVLIIASVIFGLIAAVVLDGQQRWVPLAAYLIVTMLFVKL
                     YVPTRLKKMSD"
     gene            10634..11416
                     /locus_tag="LLC22_000802"
     CDS             10634..11416
                     /locus_tag="LLC22_000802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphotransferase family protein"
                     /protein_id="HBK5434099.1"
                     /translation="MMEFQLDQEWRLRPIKGDTGKTYIGMRDEDKVFIKRNTTPMLAA
                     LSREGITPKLVWTKRTGNGDTLTAQEWLEGRLLTPNEIGQRNDVIDVLYHLHHSNSLK
                     TMLTRIGGRVMTPEKMLQKYEKELPEELQKNQFLQIVHRFLREQIPSIDKENLSVVHG
                     DVNHRNWLVCKNYLYLVDWDSIMFADPAVDIATILGNYVPLSSWNQWLISYGIRPTDE
                     MLEKFHWYAAMNLLQEITRYCKREDHRRMNEEILQLKRIFSG"
     gene            11486..12148
                     /gene="trmB"
                     /locus_tag="LLC22_000803"
     CDS             11486..12148
                     /gene="trmB"
                     /locus_tag="LLC22_000803"
                     /EC_number="2.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(46)-N7)-methyltransferase TrmB"
                     /protein_id="HBK5434100.1"
                     /translation="MRVRNRPGAAEMLAAHPNFVISDPTLWKGKWNELFENDHPIHIE
                     IGMGKGQFITGMAKAHPEINYIGVEMQVSVVSIALDKLIEQPLPNLKLLHVDGSALTE
                     YFADSEVDQIYLNFSDPWPKKRHEKRRLTYKTFLAVDEQILRPNGEIHFKTDNQGLFE
                     YSLASFSQYGMILKQVWLDLHQSQFEGNIMTEYEEKFSSKGQRIYRVEAQFQDKTKKK
                     SL"
     gene            complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LLC22_000804"
     CDS             complement(12246..14000)
                     /gene="ade"
                     /locus_tag="LLC22_000804"
                     /EC_number="3.5.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine deaminase"
                     /protein_id="HBK5434101.1"
                     /translation="METTLRKYIEVASKKKPADLVIKHAKIVNVFTKEIMEKDVAICE
                     GMIVGIGEYEGKSVHNANGQYLVPGFIDGHVHIESSLLSPSEFSKVSLLHGVTTVVTD
                     PHEIGNIAGSTGLEFMIEDARQTLMNIFFMLPSCVPVTPFETNGANLNAKKLAPFLQK
                     PEVLGLAEVMNYQAVANNETDILEKIQLMHQHKKKIDGHAAGIGMEELNVYPAAGIRT
                     DHEATTAKEAKEHLDLGMYLMVREGTVAKDLASLLPAITPENSRRCFFVTDDKLINDL
                     VKEGSIDHIVRQAIALGIDPLQAIQMATLNAAECFDLKTLGAIAPGYQADFFLTDDLT
                     KLPIHEVFYKGTLVVQSGQLQDHLFADHSNSYTCCLPKLNAQPLNPHSLELLLSSSQA
                     HVIEIIPNSLVTKDLVEKVDRQGERFIPSIEKDQLKIAVIERHHQTGNIGLGIVKGFQ
                     LKQGAIATTIAHDSHNLVVVGTNDEDMLYAANLLIQKGGGMTVVNKQQEIACVSLPIG
                     GIMTQEPFSIVYEQLNELITKAHQLGAAKTFDPFLTLSFLTLSVIPELKITDKGLFSF
                     SRFQLIPPCGKTDEINTF"
     gene            14132..15061
                     /gene="tadA"
                     /locus_tag="LLC22_000805"
     CDS             14132..15061
                     /gene="tadA"
                     /locus_tag="LLC22_000805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346292.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Flp pilus assembly complex ATPase component
                     TadA"
                     /protein_id="HBK5434102.1"
                     /translation="MEIKRLSDQMISESFAKHAQDVYILPASEVFYIYFRYGKKRTFW
                     KKVSSADGQQLISRFKYLGQMDIGEKRKAQLGAFTYSLEKQEVRLRLSSVGDYLQRES
                     LVIRLLYGTFETPHRCFSSRDFATILQKTVRRGLYLFSGPVGSGKTSLMYRLALEEKL
                     QVITIEDPVEIEEPFFLQLQINPKIAQTYDTLLRLALRHRPDLLIIGEIRDESTAHAA
                     VRAALTGHRVFATVHARNLEGTLVRIHELTKKKEELSECLAGVIYQELLEDANHHPSV
                     LWSYQFMEEESVKKSWEESYEEAQENIWQSELF"
     gene            15018..16067
                     /locus_tag="LLC22_000806"
     CDS             15018..16067
                     /locus_tag="LLC22_000806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein ComGB"
                     /protein_id="HBK5434103.1"
                     /translation="MKKLRKIFGSQNYSKGLTRSQQNQFAQTMGELLLSGFSLQESLY
                     LLLTIRSFPPVILANIQHQLKEGQAFSEVLSQIGYGAEQLVQIELAERHGNLPTTLLE
                     IAKQFRLVEGFRNDLKKLLAYPMLLLTFLLGILFSMRLFVLPQLIGSGMVMQEHWGIQ
                     LIQVFHWYVLLFILAVTLLALLVRYRLMKLSPVDQSEWISRQLLIGPIYSLYQSAYLS
                     LEIGKLFHEGFELRQIIVCLKETKQESLIQHLASKLIQGLEAGMSLAEQFQNYRFLSE
                     EFSKIVLQGEAKGSLGKELIFYSEWTRKQLFKRLHHWMHFIQPIIFLGVAALILLVYA
                     AVLLPVYGSIEEVLP"
     gene            16064..16342
                     /locus_tag="LLC22_000807"
     CDS             16064..16342
                     /locus_tag="LLC22_000807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin-type N-terminal cleavage/methylation
                     domain-containing protein"
                     /protein_id="HBK5434104.1"
                     /translation="MKKRKISYYSGFTLIEMLIVLLIISVLVLLFVPNLSRYRNHVDQ
                     ESREAIIQLVDTQKELYALQNNGRVPTVEELLNEGYIKREHAEIYQRP"
     gene            16317..16787
                     /locus_tag="LLC22_000808"
     CDS             16317..16787
                     /locus_tag="LLC22_000808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II secretion system protein"
                     /protein_id="HBK5434105.1"
                     /translation="MQKSISGLEGKVLASGYTLFESLLLILLLTTILSFPVLAFSAWK
                     NELAVYQFFGQFEKRIYSTQKIAIVNQIQTGFYWNSEENQIIFHVPNPDKINWEVLDI
                     PDEITLKRHASITFAARTGNESSLKAYQFYWEEKERTITYQFQIGSGRYTKRIE"
     gene            16804..17106
                     /locus_tag="LLC22_000809"
     CDS             16804..17106
                     /locus_tag="LLC22_000809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434106.1"
                     /translation="MESLTALMIASVCVYLVSFGQLFLLQAEKKSGEELLFIRMIYED
                     IKTQRMYHKRPERREEMIPYDIQIVDNNGVIEKVFVNMEKEAISIEKTSNSSIYAD"
     gene            17123..17494
                     /locus_tag="LLC22_000810"
     CDS             17123..17494
                     /locus_tag="LLC22_000810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComGF family competence protein"
                     /protein_id="HBK5434107.1"
                     /translation="MILSSLLLTFNLLIQQTIQVSEFLQRKDQKEWLIFLAQLEEELK
                     SSHNVSVKNQQLHYTIEDKQYIIERYQAMIRKRRTSGGHQPMLTSITELQLLEKEHTI
                     SFYVHFENGEDGYAIWTKNDQ"
     gene            17466..17825
                     /locus_tag="LLC22_000811"
     CDS             17466..17825
                     /locus_tag="LLC22_000811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434108.1"
                     /translation="MPYGQKTISRKCYKGSILFSVLLLFLLCTFLLMAALESYRLSMD
                     LNIRIKNYYIAKIMKQMALSEQSTLAESSEGVFYYTTGSVTYQWVQQSLFLEVEVSPF
                     IFRFTEEVKNDTDTSTE"
     gene            17997..19004
                     /locus_tag="LLC22_000812"
     CDS             17997..19004
                     /locus_tag="LLC22_000812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5434109.1"
                     /translation="MLPEKMEQGFNQNLEAIQLLQNALGTSFLEAYVENAENLIDDYQ
                     VRVVDGVPTKETTQRITALYEELKKLSFEPEEWRRLSQLLLLKGSQTEHLQANHQLTP
                     DSIGFLFVFLIEQLYTNKKAPVKILDIAAGMGNLLLTVLLNLSNAGYQTEGIGVDIDD
                     TLLAVAASTSDLTQANVQYFHQDGLQELLIDPVDFAISDLPIGYYPNDEKAKEFLTST
                     EEGHSYAHHLLLEQSMKYVKPDGFGLFLMPSGFLETDQSEEIKKWFKEEGYLQGMIQL
                     PDELFRNKQSQKSILILQKKGPQAQQVKEVLLVKLASLKEPEKVTEFFNEFKNWKSSA
                     L"
     gene            19029..20213
                     /locus_tag="LLC22_000813"
     CDS             19029..20213
                     /locus_tag="LLC22_000813"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetate kinase"
                     /protein_id="HBK5434110.1"
                     /translation="MSKTIAINAGSSSLKWQLYQMPEETVVAKGIVERIGLQDSIFTI
                     KYGDNQKFEQIMDIENHEVAVKMLLDQLIELQILSSYDEITGVGHRVVHGGETYGDSV
                     VIDEKVMDRIAELAEFAPLHNPANLMGIKAFKKILPDILSVAVFDTSFHSTMPKQNYL
                     YSLPVSYYEDFKVRKYGFHGTSHRYVSERAAKLLNKPIEELKIITCHLGNGVSITAVD
                     GGKSMDTSMGFTPLAGVTMGTRSGDIDPAVLPYLMEKLEIDIDEMINVLNKKSGLLGL
                     TGLSSDMRDLEKNYEKEHIRLAYDIFVDRIRKYIGGYVTTMNGVDAIVFTAGIGENDG
                     HVRSEIIKGMSWFGCEIDPALNELRGEEVDISTKESKVRVLVIPTDEELMIARDVERL
                     RG"
     gene            complement(20650..22233)
                     /locus_tag="LLC22_000814"
     CDS             complement(20650..22233)
                     /locus_tag="LLC22_000814"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5434111.1"
                     /translation="MIIQAISIKKTIGGNPLFEDLSCQIEAGEKIALVGINGTGKSTF
                     LQILTGREGVDSGVISRKKGLKIGTVEQELTVSEATVNHYLLHSAAEIQDLKQQMSRY
                     EALMTEPDTNLEKCLARYGELQHRFEELGGYVLEDRIAAILQGLGIPHRQEARLTELS
                     GGERVKVALAKILAADADLLLLDEPTNHLDLNSIRWLENYLQNTKKSVLVVSHDRQFL
                     DQVTTKTWELEEGALIEYPGNYSRFRVLKEARLAELTKNYELQQKEVQRLKVMIRRFR
                     QWAHEGDNESFFKKAKELERRLAKLTLVKPPPPPKNRLQSLSNGGKSGKEVFIIQNLH
                     QQYADQVLFKDSSFAVYRGDHLAIIGDNGAGKSTLLKLLLGEEKPYGGTIKLGSSLQI
                     GYLPQQLQFADPDSRLLAYAITLTGNEEVARRQLAKSGFYQSDVGKRIKDLSGGEKIR
                     LALLKLFLEKINVLILDEPTNHLDSYAREEIEEMLQDYQGTLLAVSHDRYFLQQHFQE
                     ALVIDQEQISRQPLGQLID"
     gene            complement(22811..22954)
                     /locus_tag="LLC22_000815"
     CDS             complement(22811..22954)
                     /locus_tag="LLC22_000815"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="portal protein"
                     /protein_id="HBK5434112.1"
                     /translation="MEVSDESDTKKYEVSMADTDFIAKLKFYFGFGYREKASATFGKS
                     FKN"
     gene            complement(23177..23656)
                     /locus_tag="LLC22_000816"
     CDS             complement(23177..23656)
                     /locus_tag="LLC22_000816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337968.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5434113.1"
                     /translation="MLQQYKKIMVAVDGSDEAELAFKKAVNVAIRNNGELLLAHVIDT
                     RSFQTVSSFDGMLAEQATEMAKQTLADYESNAKKAGLNNVTSVVEYGSPKQIIAREIP
                     EDNQVDLIMLGATGLNAVERLFIGSVSEYVIRNAACDVLVVRTDLENQLPAKDHTKA"
     gene            complement(23729..24013)
                     /locus_tag="LLC22_000817"
     CDS             complement(23729..24013)
                     /locus_tag="LLC22_000817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434114.1"
                     /translation="MIRILMIIATLVLLFVSYYLFNKQDIFFVLINKNDKNQGFLQFY
                     GAAYAVLGVMGILTAFFNQRFIALVFLLIVIIVSATFSIRFAKKIAEPKQ"
     gene            complement(24091..24285)
                     /gene="ssrS"
                     /locus_tag="LLC22_000818"
     ncRNA           complement(24091..24285)
                     /ncRNA_class="other"
                     /gene="ssrS"
                     /locus_tag="LLC22_000818"
                     /product="6S RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00013"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00013"
     gene            complement(24357..25643)
                     /locus_tag="LLC22_000819"
     CDS             complement(24357..25643)
                     /locus_tag="LLC22_000819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication-associated recombination protein A"
                     /protein_id="HBK5434115.1"
                     /translation="MQQPLAYRMRPRTIDEVVGQQHLVGEGKIIRRMVDARMLSSMIL
                     YGPPGTGKTSIASAIAGSTNYAFRMLNAATDSKKDLQVVAEEAKMSGTVILLLDEVHR
                     LDKTKQDFLLPHLESGRIILIGATTENPYITINPAIRSRTQIFEVKPLTEQDIQLAVE
                     HALRDKERGLGQQAIQLDEDALLHLSRATNGDLRSALNGLELATLSTPSDKEGRIHLT
                     LSIIEECVQRKALTHDKNGDAHYDVISAFQKSIRGSDVDAALHYLARLVEAGDLASIC
                     RRLMVIGYEDIGLGNPAAAARTVNAVLAAEKLGLPEARIPLADVVVDLCLSPKSNSAY
                     MALDAALADIREGKAGDVPDHLRDSHYKGAKSLNRGVGYQYPHHFDQAWVNQQYLPDK
                     LKSAQYYQPKDTGKYEQALGQQYYRIKEWKKHPPKN"
     gene            25781..26452
                     /locus_tag="LLC22_000820"
     CDS             25781..26452
                     /locus_tag="LLC22_000820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289090.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase"
                     /protein_id="HBK5434116.1"
                     /translation="MTDKQKIDEFFWNKTTPEVARDLLGMYLEHDTPEGRLAGYIVDA
                     EAYLGPEDEAAHSYGLRRTPRVRAMYEKPGTIYLYTMHTHRILNIITQPEGIPQGVMI
                     RAIEPAAMIDQMSKNRGGKTGPDISNGPGKLVEALAIPQELYGQSIADSSLRLVFEKK
                     KTPKKINALPRIGIPNKGVWTEKPLRFVVSGNPYISLQRKNQIEKDWGWRKENEKEGS
                     INIFR"
     gene            26418..26906
                     /locus_tag="LLC22_000821"
     CDS             26418..26906
                     /locus_tag="LLC22_000821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3013 family protein"
                     /protein_id="HBK5434117.1"
                     /translation="MKKKDLLTYLDEIIEKQVTDYDVALDWDTKNHTIEIVVRLFAEN
                     KAQFEIDDAEGIVSQEPIIEFEDGVLLFNPQKSVFDERNYLAVIPYEGKKGLAKSVAD
                     SLVEYLNEVLAQGQSDLLDFLDEDDDEAVFELHWDNQQLAELVEVKQQNEADTYLPYP
                     SY"
     gene            26919..27866
                     /gene="prmA"
                     /locus_tag="LLC22_000822"
     CDS             26919..27866
                     /gene="prmA"
                     /locus_tag="LLC22_000822"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11 methyltransferase"
                     /protein_id="HBK5434118.1"
                     /translation="MKWNEVKVETESEAVEAVANILMEAGASGVAIEDSLDVEHFQSD
                     QYGEILDKNDFTSLKEGALVMAYFPETTFLPEILPFIKDRITQLPEFGLAIGKNKVTV
                     SEVEESNWATAWKKYYHPVRITRMLTVAPSWENYQTEDPLEKIITLDPGMAFGTGTHP
                     TTSLTLTALETVLRGGETLLDVGTGSGVLSIAAKYLGAKDVYAFDLDEVAVRSAKENM
                     DMNEIAKDVHVSANDLLTGIEIESDVIVANILADIILLMIPDAWRLLKQTGTLIVSGI
                     IEEKKQMVLDAMLEQGFIVDQIFQQKDWYAIILKKPEVE"
     gene            27867..28631
                     /locus_tag="LLC22_000823"
     CDS             27867..28631
                     /locus_tag="LLC22_000823"
                     /EC_number="2.1.1.193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (uracil(1498)-N(3))-methyltransferase"
                     /protein_id="HBK5434119.1"
                     /translation="MQRYFLKESYESKDYFVLEGENYHHIVRVMRMEPEDEVFLAFND
                     QIAIVAEITEITEEAVYLKEIKKEENQKELPSSITIASGYPKGEKLDWIVQKSTELGA
                     QAFLGFPASASVVKWDAKKRMKRQQRLEKIAQEAAEQSHRQIVPSVELLETKQDLFER
                     LDDYDVVLVAYEESAKQGEKSNAAKILSETKPDSRILAVFGPEGGLSRDEVDYFVEHK
                     GILCGLGPRILRTETAPLYLLSAASYQWELMNPSFS"
     gene            28864..31077
                     /locus_tag="LLC22_000824"
     CDS             28864..31077
                     /locus_tag="LLC22_000824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016616266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional (p)ppGpp
                     synthetase/guanosine-3',5'-bis(diphosphate)
                     3'-pyrophosphohydrolase"
                     /protein_id="HBK5434120.1"
                     /translation="MTKEEILTGPGVIKLVSQYMGPEHVAFVEKACEYATAAHDGQFR
                     KSGEPYIIHPIQVAGILADLKMDPHTVATGFLHDVVEDTEITLEDLREEFGDDVAMLV
                     DGVTKLGKIKYKSHEEQLAENHRKMLLAMAQDLRVIMVKLADRLHNMRTLKHLREDKQ
                     RRIAQETLEIYAPLAHRLGISRIKWELEDTALRYLNPKQYYRIVHLMQTKREEREKYV
                     SGTVEDIRIATEELGIFAEIYGRPKHIYSIYRKMKDQKKQFNEIYDLLAIRVIVDSIK
                     DCYAVLGAIHTKWKPMPGRFKDYIAMPKANMYQSLHTTVIGPAGNPVEIQIRTQEMHE
                     IAEFGVAAHWAYKEGKNEKVEPDGMTKQLSWFHEILELQDESYDASEFMEGVKGDIFS
                     DKVYVFTPKGDVTELPKGSGPLDFAYSIHTDIGNKTTGAKVNGKMVQLDYKLKNGDII
                     EIMTSPNSFGPSRDWLKLVATSKARNKIKRFFKAQDREENVIKGHESVVKCITDLGFT
                     PKDILTKNKLQEALDRFNYQTEDDLYAAVGYGEVSPLTMANRLTEKERKEQKIEQQKQ
                     EAEEIMNQPKKEPDKMKVRHEGGVVIQGVENLLIRISRCCNPIPGDDIVGYITKGRGI
                     SIHRRDCPNVQPDKPNVAERLIEVEWEDTSNTRKEYDADLEIYGYNRSGLLNDVLQTV
                     NALTKNLNSVEARTNKDKMATIHLTVGIQNLSHLKSIVDKIKAVPDVYSVRRTNG"
     gene            31088..31534
                     /locus_tag="LLC22_000825"
     CDS             31088..31534
                     /locus_tag="LLC22_000825"
                     /EC_number="3.1.1.96"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-tyrosyl-tRNA(Tyr) deacylase"
                     /protein_id="HBK5434121.1"
                     /translation="MRAVVQRVSKAAVSVDQQEIGKIGYGLLVLLGIHETDTQKDVDY
                     LVKKIAQMRIFEDEQGKMNISVEDVGGQILSISQFTLFADTKKGNRPSFVEAARPETA
                     IPLYESFNEGIRSRGITVATGQFGADMSVSLVNDGPVTIIIDSKNK"
     gene            31705..32964
                     /locus_tag="LLC22_000826"
     CDS             31705..32964
                     /locus_tag="LLC22_000826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cytochrome P450"
                     /protein_id="HBK5434122.1"
                     /translation="MKEVPVVDIKITDLKKLYQKGYNMLEELRHEADAPVVKAKIFNK
                     EAITIYGSSAAKVFYDPRNFKRKGAMPKLVLKTLFGQGGVQTLDGAAHHHRKNIFMDL
                     MTPERMEDYHRILDKNLTQALEAQHGQFELFDLSKMVFFTSICEWAGINLSAISKDEV
                     EKLAEYQISMISGTFTSPIDHIKGVENRKKSEKWAQGLIEEARQNPVAGKENVALYAF
                     ANATDLDGQLLPLEVAAVELLNIIRPTVALTVWAALMGHALFSRPDLYQQLKNDFSTL
                     QDPFIQEMRRYYPFFPMLPAISLKEVEVDGYRIPEGSWVILDLYGTDHDERTVEAPDS
                     FMIKRYVGKAKDISYKEEYEMIAQGGGNFRQMHRCAGEWITLHSLRVFSDQLVNKFEF
                     SVPEQDWTIPFNQFPTYPNSRALLYKN"
     gene            complement(33053..34000)
                     /locus_tag="LLC22_000827"
     CDS             complement(33053..34000)
                     /locus_tag="LLC22_000827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5434123.1"
                     /translation="MAEIRIGHSQVYAEQLGLGANAVGGHNLFDGLEDETGKQVVRTA
                     LNSGINLIDTAYAYGNGRSEELIGEVLKEKEYDRSRVVIATKAAHVPNKGRTFDNSPE
                     FLKQSVEDALKRLQTDYIDIFYIHFPDESTPKNESVATLHELKEAGKIRAVGVSNFTL
                     EQLKEANADGYVDVVEDKYSLIHRQAEKELFPYLEKNKISFVPYFPLASGLLTGKYEL
                     GEEKQFGEGDPRKRNPDFQGERFREILTAVDVLRPIAKRYQATPAQLVLAWYMKNPRV
                     SVVIPGAKRPEQVSDNVQALDLHLSNEDYQTIDEAFRGF"
     gene            34394..35686
                     /locus_tag="LLC22_000828"
     CDS             34394..35686
                     /locus_tag="LLC22_000828"
                     /EC_number="6.1.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine--tRNA ligase"
                     /protein_id="HBK5434124.1"
                     /translation="MSFQRPKGTNDILPGESEKWQFVEETARLLFRDYQYNEMRTPIF
                     EHYEVISRSVGDTTDIVSKEMYDFYDKGERHVTLRPEGTAPIVRSFVEHKLFGPEYAK
                     PFKTFYMGPMFRYERPQKGRLRQFHQIGVEAFGSENPATDVESMVMALDFFKQLGITQ
                     IRLVINSLGDKETRQAYRQALIDYLLPFESELSEDSKRRLHENPLRVLDSKDKRDQKF
                     VAEAPSILDYLSEPAQKHFDTVVSMLDALAVPYEIDSNMVRGLDYYTHTIFEIMSDAP
                     KMGAQATICAGGRYDNLVEELGGPSTPGFGFAMGIERLLLTMEAEEVVIPAFNELDAY
                     VVALGDETNIEALKVVQAIRNFGFSADRDFMNRKAKAQFKTADKANAKLVLVIGEDEL
                     ASQTINVKAMASRKEKSFPLEEIYEHFDEVYDEMTLFE"
     gene            35701..37470
                     /gene="aspS"
                     /locus_tag="LLC22_000829"
     CDS             35701..37470
                     /gene="aspS"
                     /locus_tag="LLC22_000829"
                     /EC_number="6.1.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate--tRNA ligase"
                     /protein_id="HBK5434125.1"
                     /translation="MAQRTIYCGLVSEQQLEQTVTLKGWVQKRRDLGGVIFIDLRDRE
                     GIVQIVFNPEINKEAWEIADKCRSEYVIEVTGEVRRRGENAVNPKMATGEFEVIASEI
                     VILNQAKTPPFQIEDDQAISDEIRLKYRYLDLRRPKMTKNIKLRNATTKAIRHYLDDN
                     DFLDIETPYLGKSTPEGARDYLVPSRVHAGHFYALPQSPQLFKQLLMNAGFDRYYQIV
                     RCFRDEDLRGDRQPEFTQVDIETTFLTAEEIQTYTEGLIAKVMKEVRGIEVTLPFPRM
                     TYDEAMARYGSDKPDTRFDMELIDLSDTVKEVEFKVFQMALENGGVVKALNAKGAADR
                     YSRKDMDQLGQYVGQFGAKGLAWLKVEEDGLKGPIAKFMGEATEAIIKATDAKPGDLL
                     MFGADKSEIVAAALGAIRTRLGKELGLIDESKFNFLWVTDWPQFEFSEEEGRYVSAHH
                     PFTMPKEEDIPLLAEDPAKVYAEAYDIVLNGYELGGGSIRIHTRELQEKVLETLGFTK
                     EQMEEQFGFLLTALDYGFPPHGGIALGLDRFAMLLAGEDNIREVIAFPKNGKAADVMS
                     DAPSMVSPLQLFELNIDVTNIEE"
     gene            37579..38454
                     /locus_tag="LLC22_000830"
     CDS             37579..38454
                     /locus_tag="LLC22_000830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5434126.1"
                     /translation="MKKTFENWAYHDYTTKLSVSIVYALIASVALNFFYQPGHIYSSG
                     ITGLAQILTTLSKSLIGFEVPVSTTLYLLNIPLFVLAWLKIGKKFTIFTFITVTLTSL
                     CIHILPETVLSTDPIICALFGGAVMGLGIGLALRNGLSSGGLDIVSITIRKKTGKSIG
                     SISIYFNALIVFVAGILFGWQYMFYSTLSIFVSGKVTDVVYTKQKKMQVMIVTKHPEK
                     VVNEIQNCMRRGITIINEAEGAYKHDKQTVLMTIVTRYELPLLREAMKASDPQAFVSI
                     AENVQILGRFYEDGI"
     gene            38720..40603
                     /locus_tag="LLC22_000831"
     CDS             38720..40603
                     /locus_tag="LLC22_000831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBK5434127.1"
                     /translation="MEKQKRLKNSRYITGFDGLRSLAVVGVIFYHLLPTSMKGGYLGV
                     PIFFVVSGYLITDLLRQEWEQNGKINIWQFYVRRMKRLYPALVFMLVTASAYITLFQR
                     GLLNNLRGVVVSSLLYVNNWWQINNGLSYFDRFANESPFTHIWSLAVEGQNYLVWPIL
                     FVLLMVFVRKRKWIFYTVLGTSFLSAILMMILYTPGGDPTRVYYGTDTRLFSIWLGSA
                     LAFVWPSTRLKKNIPKQAKNILNIAGGISLLALILCFFFLDDHYNFIYYGGMLLVSLL
                     CVVLVAVTAHPGASLNRWLTNPVFTWIGKRSYGIYLYQFPVMIFYEAKVTDIADHVLL
                     HTLVEITLILIISELSYRYVERPLARFDYGRTFQVMKGWFSKPIISKSKPWVVPGTLL
                     VAIALVGFVTAPKNAVTADQKQLQAKIAESKKLAEETRNNSENTTSSVDQAILDKYEL
                     SKAQGNKAQKLELTAFGDSVMLDAATDLQELYPKVVVDGDVGRQLYASVPYIEKLKEQ
                     DLLKDTVLIGLGTNGSFSEAQFDSVMDAIGDRKVYWVNVRVPTKRWQNDVNAMLEQMT
                     KKYDNMTLIDWYSYSNDHSDWFYDDQVHPNPEGMTHYIHLVSEALLGGSSSTNSSETN
                     VTE"
     gene            complement(40678..40962)
                     /locus_tag="LLC22_000832"
     CDS             complement(40678..40962)
                     /locus_tag="LLC22_000832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK5434128.1"
                     /translation="MANEHYFYVLFCKDQTFYGGYTTDLSRRLEEHNNGTGAKYTRLQ
                     KRRPVKMIHAEVFSSRSEATKAEAAFKKLTRKQKERYLQTHSTVLLPESI"
     gene            complement(40952..41686)
                     /locus_tag="LLC22_000833"
     CDS             complement(40952..41686)
                     /locus_tag="LLC22_000833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341140.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA1(Val) (adenine(37)-N6)-methyltransferase"
                     /protein_id="HBK5434129.1"
                     /translation="MLHEDERIDQLYAEDIKIIQSSKVFSFSLDAVLLAHFSRVPKKG
                     KIVDLCAGNGAVGLFLSKRTQAAIDAIELQPRLADMARRSIALNHLNEQMTVHTIDLK
                     DSLSVVRHNSCDLVVCNPPYFKGLPTNKTNPNKHLAIARHEIHTTLEEVIDISSKLLK
                     TNGRFTMVHRPDRFLEIIQVMEDYRIAPKRIQFVYPKPGKEANILLVEGIKEGKLDGF
                     KVAPPLITYNMDGEYTAEIREMLYGK"
     gene            41815..42438
                     /locus_tag="LLC22_000834"
     CDS             41815..42438
                     /locus_tag="LLC22_000834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-acyl-sn-glycerol-3-phosphate acyltransferase"
                     /protein_id="HBK5434130.1"
                     /translation="MFYRFMRGVVRVLLALVNGNARYENKEVLPQDENYILVAPHRTW
                     WDPLYLAVAAAPKEFSFMAKEELFKNPVLRFILTRSNAFPVKRENPGPSVIKTPVKIL
                     KSTNLSLIMFPSGTRHATELKGGMALISRMSKAKIVPAVYQGPLTLGDLFKRQRVTVR
                     FGEPIDLSDIKKTDKEGMAEIERRTQAAFDKLDKEVNPDFKYEVKKK"
     gene            42630..43751
                     /locus_tag="LLC22_000835"
     CDS             42630..43751
                     /locus_tag="LLC22_000835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease SbcCD subunit D"
                     /protein_id="HBK5434131.1"
                     /translation="MRFLHTADWHIGKKLQGYDLIEDQRHVLSSILDIAKEEKVEAIV
                     IAGDLYDRSVPAVDAVELYNELMVDWNLKEKIPIFAISGNHDSSTRLSAGTPWFSYSN
                     YFLRTQLAEAFEPVEFKNVQFFFLPYFEPIAARLYFEDDNIRTIKQAVAKVIDKMQEL
                     FDSEKKQVLISHFFVMGSVKSDSETKIEVGGLDSIPGELLTPFDYVALGHLHNQAALR
                     QDNARYSGSPLKFSLSEINQKKGVWIVDLTTGLELNFREIEPLHDIEEITASFKELLD
                     PAFYQSVNRENYIYIYLTDRTIIPNMMNQLRQIYPRILGIERANGRAEQTKRKRKVLE
                     MKDPQKLAEAFFSEMTEEQLTANQEKWLGETLQEIMEME"
     gene            43758..46886
                     /locus_tag="LLC22_000836"
     CDS             43758..46886
                     /locus_tag="LLC22_000836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC family ATPase"
                     /protein_id="HBK5434132.1"
                     /translation="MKPKKLQLKNFGPFINETVDFSRLTEAPLFLISGKTGAGKTTIF
                     DGITFALFGETSGRLRSGKEMRSLFATPDEETSVTFSFEHQQMSYEIERKPEQVLAKR
                     KGNGTKKQAAKVTLTIFDGKGKEIKQITKRTEADQLIRELMNLDAKQFSQIVLLPQGE
                     FRNFLVSSSSDKETVLRHLFGTQFFQQFNERLKEKAKQQQQKLDHLEQELHLLQKRFV
                     LVKEEEPAAGFEAVLAQWTNHQAILEKQITEEKEALTELQEKQKQLENSYYRFESLKK
                     SYEEKTILINKQKELAAQKDEIEEKKRWIGYYEFTQRLVEPIQRLQEIKVEKIELSQK
                     SSEQTKKLAMTTQNYEEWQKNEANRVRRQTKIKEAAQKLQNKQMMVPIVESLRSKKQD
                     AEQLTISLDKEELNAEKLYQNLAIYQERTRILQENLLDQEKLQEDRLAFGQLKYLDEK
                     QQEIEKQKAKDTGSLAQIREELKKATEEITKNSQLLKEQTEQAEQLKSQWAKQQIARL
                     QLFLRPGEPCLVCGSTEHPIQQLKHEQPNKEDILKVEQQLAEAESAVERTQQIIAKSE
                     AHENNLQQQLSDLEQKIMATNIQLAEQEEHLQQALKKAFPEITEQKTKTTLVVIEQSL
                     DRRKSKMANARIELEEIRQQAEKLEQQLAVYKQQQTEKNNQLQQLQGEIKSLEQQLQD
                     TDSNCLEEEIRRLEKQLEEDSNQLAVEQKAGVQLLQDLHTLRTQLDLQHEQIEKIDEK
                     IEKEQERIAKKLESQSYFSTIEEICAFAQQQAQYKENQRTVTSYHEEQLVTADRLRQL
                     ENIQLTETFPDTEEISQQLEEIRRMIEIKQEKIYGLQEQKISNQKIYDECLSIYHTSQ
                     TKLDELTQLQQLSQTFNGENPKKTSLERYVLQVYLQEVLQVANDHLQRLTKNRYQFEL
                     ADTIGSYRGKTGLEINIYDDQAGMSRSAHTLSGGESFIAALSLALALADVIQTQAGGV
                     AIDALFIDEGFGSLDEEALEMAMEALETIESEGRMIGIISHVRELKERVLQQIRIDTE
                     GSGQSKIRYQLG"
     gene            46905..50099
                     /locus_tag="LLC22_000837"
     CDS             46905..50099
                     /locus_tag="LLC22_000837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SNF2 helicase associated domain-containing
                     protein"
                     /protein_id="HBK5434133.1"
                     /translation="MKWSIPEKVIARGRQYLQEGRVLSVVPDQEENVWHAEVLGSELY
                     MVDLDGTAKEIDYCQCPYWEEHKYCKHTVAVELYLRSKNLSRIMKKDQPMLEPVKATS
                     EGEIIAKGFSRLKTQNNPQAVQPLIIEYQVETIETNQYHPELSILALYLRIGSLASPK
                     KTYIVKNIYDFLQAYTEKETYTVNKQYQFRLDKRAFQKEDQKILTHLAGSAQTHQLLG
                     TNGLQVKGKLDKRYLLLPVEQARFLLEQMNQTTRLHLQINEQNDQGIQFSDQNKPLSF
                     KVEKFGEDYLLQALNDFDFFFMHYQWGVIQGTFYSLTKYQQTVYQTWKQLIRRLEKPE
                     VVFKKKELPSLFKEIIPLLSEIGDVAIAPAVEEEVADIPVEFIFFFRKAKGKIQARVD
                     FVYGEVIYSTDPKHEVSTEQAFQVLRDTVEEKRVLDLFRMYRYQKNETGYERPLPSGE
                     ELYAFFRTELSVFRQFGEVRLGRKLRELYLDAHKHQPKIEVTETGSWLDIRFDVTGIE
                     EQEIDHVLQSLLRNDAFYTLENGQVLSFDSEEFQQTSQVLQQLRESIRTEEGTIHVPK
                     NQGLIIQNQLEKSNATFSESFQTMVQDLIHPERYQAQLPKGLNATMRDYQKQGFRWLK
                     MLGHYQFGGILADEMGLGKTLQTIAFLLSEKEERKSFSALIVAPASLIYNWQAEVRKF
                     APSLSIQVINGNKKEREELLAKDTDIRVTSYASLRQDLANYQSQKIDYLILDEAQMVK
                     NSSTKTAQALRELAVPQRFALSGTPIENNLEELWSLFATIMPGFFPTKTKFRELAAEE
                     IAQMIRPFILRRDKQTVLKDLPEKTEMNLYSALTEEQKTVYLAYLRQMREEITSMDSE
                     AFKKNRIGILAGLTRLRQICCDPRLFIEDYQGGSGKLEQVKDLLVAAKENKRRVLLFS
                     QFTGMLTILQEELAELGISTFYLRGSTKPQDRLSMVDAFNAGEKDVFLISLKAGGTGL
                     NLTGADTVILYDLWWNPAIEEQAAGRAHRIGQKNVVEVWRMISEGTIEERMDSLQQEK
                     RELFQKVIQGNEEQLTKLTEEDIRMILSVGEIEE"
     gene            complement(50245..50952)
                     /locus_tag="LLC22_000838"
     CDS             complement(50245..50952)
                     /locus_tag="LLC22_000838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK5434134.1"
                     /translation="MIKSVVFDVDDTMYDQQQPFRNAVKRVVPLVSDADMHPLYIRFR
                     HHSDENFPKVMAGDWTLEYMRAHRISQSLKDLDYPHITEEDGLLFQKIYEEELDNICL
                     HEEVKKTLDFLKEKNVPLGIITNGPTDHQTKKLKQLQLNNWIPSRNMLISQATGFQKP
                     EKEIFQLAEKEFHMLPEETLYVGDNYDNDVLGAKSANWQALWFNHRERKIEQTPICDI
                     EISSFDQLLETMKTIFV"
     gene            51717..52115
                     /gene="spxA"
                     /locus_tag="LLC22_000839"
     CDS             51717..52115
                     /gene="spxA"
                     /locus_tag="LLC22_000839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBK5434135.1"
                     /translation="MLTLYTSPSCTSCRKARAWLQEHQIPFVERNIFSEPLNSSELKA
                     ILQMTEDGTEEIISTRSKVFQKLNMDLDDLPLQELLELVQNNPGLLRRPIMIDDKRLQ
                     VGFNEDEIRRFLPRDVRQLELRQAQLMAGL"
     gene            52447..53100
                     /locus_tag="LLC22_000840"
     CDS             52447..53100
                     /locus_tag="LLC22_000840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adaptor protein MecA"
                     /protein_id="HBK5434136.1"
                     /translation="MEMEHINENTIRVLIGHEDLEERGVSFLDLLGNHKEIENFFYSI
                     LEEVDIEEEFRGSEAVTFQVLPKGDGLELFISKNLPDEEISQSEDSTVDSEDVSDFLR
                     QQIIGSDPEEELSGSALEEQERQATFAFEDFEQVIQLATDVELESAWTDLYLFEERYY
                     LVVHFWMENLNQADVENQIARILEFAEKSDRTPETLNEYGQCLMARNAIERTKFYFV"
     gene            53326..54324
                     /locus_tag="LLC22_000841"
     CDS             53326..54324
                     /locus_tag="LLC22_000841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318540.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence protein CoiA"
                     /protein_id="HBK5434137.1"
                     /translation="MLLAMNEYNKCCFAKHAEKGKKYYCRGCRKRVILKKGKKKCAHF
                     AHQKSDNCSVFSERESKEHLQLKECFMDWLGQSVEPVFLEAYLPRLRQRPDILLANLA
                     IEIQCSRLSHQRFIERTQNYLNNSYQVWWILGNSFLGQSQFSLIEKSCCYYNRKRGVH
                     CWKADLKKQKLYLYHHITETVSGHISFCSSCWTFSSRDLKEIFTSNEIKMNQMKKIEK
                     VSEDGKKWLTRQLIHKQKNTVSIQEQCYLRHKHLLHLSSWIYQKSRFFFYLQEQVFLY
                     RMLYEEALENQKVPDFNSWLCQIKEHKREWLFPMIDEEMVYQQFFNECIHLSSLKK"
     gene            54500..56308
                     /gene="pepF"
                     /locus_tag="LLC22_000842"
     CDS             54500..56308
                     /gene="pepF"
                     /locus_tag="LLC22_000842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336686.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligoendopeptidase F"
                     /protein_id="HBK5434138.1"
                     /translation="MEVKQLPKREELPENLTWDLTKIFSSDQEFDEKYLELSEELKQS
                     EKHKGTLDQGASQFLNAIEFVLRVYRQTEVIYVYAHLKNDQDTGNTDYQALYARASSL
                     FSKVSEAVSWFEPEILQLSDDQIWQYFKEEPKLEVYRHYIQQIVDNRAHVLSAEQESL
                     LAGAGEIFDASSDTFAVLNNADLVFPTIEGENGEIVQLSHGVYGQLLESTDRRVREAA
                     FKGLYSVYEQFRNTFASTLGTHIKGHNFKAKVRNYSSAREASLSNNHIPESVYDTLVD
                     VVNKHLPLLHRYMELRKRLLEVEKLHMYDLYTPVLGEAPITFTYEEAKEKALEALKPM
                     GEEYMAIVEKAFSERWIDVVENKGKRSGAYSSGSYDTNPYILLNWHDTLDQLFTLVHE
                     MGHSVHSYFTRSNQPYVYGDYSIFLAEIASTTNENILTEYLLETEKDPRVRAYVLNHY
                     LDGFKGTVFRQTQFAEFEHFMHTEDEKGVPLTSEYLSDSYGKLNAKYYGPAVEEDPEI
                     KFEWSRIPHFYYNYYVFQYSTGFSAASALAKKILNQEPEALENYLAYLKAGNSDYPVE
                     VMKKAGVDMTQAAYIEDAMSMFEQRLNELEELIDRL"
BASE COUNT        18555 a         9727 c        11686 g        16419 t
ORIGIN      
        1 aaggcaaaaa gatgaactag aaatagttca tctttttttg tttaaatctt ttgctaagtt
       61 gaactaatag agtcttttat gaatatcgaa gttagttttt cacctaactt cgttttttat
      121 agttggttat tataaaatag taatatagct gatttggatt caattcatat ttatttataa
      181 atcaaaaata cagagaatag tatataaatg tcctttccta ttcttaaaat gatgtttgta
      241 cttacttaaa ttaggtataa ttagtatatg ttttgtgaga aatttagact tacaataagc
      301 agtgaattta taatcaacgt ataggagaca tggatgaaat gaaactaatt ggtatagatt
      361 tagacggtac tcttttgaat tctgaccaga gcattagtca aaaaaatgca agaacaatga
      421 aacatttacc ggaagactgt tttccattca tttgttctgg aagagaagta gaagacatta
      481 ataatattct caaaaaatct ggtttaagga taccagcagt agggttaaat ggttctgttg
      541 gatttgatgg agaaaaaaag atatttgagt cttccttcga taaaaatgat gtaaaaaaaa
      601 ttgattctgt cctatcgaaa tttccaacca aaatatatac aaatctcgga agttatgaat
      661 ctcagaatta taaaaataaa atgaaaaaaa tttttcacga ggtagggagt gaattttcta
      721 tcaaagagct aaactatgag cttgagtatg aaaaatctat ttgttcaatc ccttataata
      781 atattgagga aattatagaa aaggatgcta tcagcattta caaatttttt atttttattc
      841 ctaatcgtca attgaaagct aatatattta accatttgaa aaagatgcta aatgtgtctg
      901 ttactgaatc ggcacctgta aatattgaaa tcgtacctca aaatgtatct aaaggtgtgg
      961 tgtttgatcg tttggaatca atctacaatt taaagaaacc tttgagaatc gcgatcggag
     1021 atagtttaaa tgacttatct atgtttgaaa gtgcagatat tagttttgca atgggaaata
     1081 gtcatcaaga aatcatgaaa aaagctgatt atgtcactgt ttcaaatgat aaagacggag
     1141 tatctcaagc atttgaaaga attcttacca tataaactaa ttaaggtagt atagaacata
     1201 gaattctaaa tacggaaaaa tggagcataa attccagtac aaatagtact tcttcagtgt
     1261 caaacgaagc gaatataaca tagatattta ggattgtgac aaaaatcatg tcacaatctt
     1321 tttttcgaat aaacttattt tttgaagtcg gccatttatc gtaatttctt tgcataatac
     1381 gaacaaattt tcggttattg atgaaaaaaa acattgaaaa tggtatgata aaagaaaaaa
     1441 aggaggaaat ttttaatggt gaaatttatc catgcggcag atttacatat ggatcggtca
     1501 tttgaaggac tgacaactct tgataaaact gtacaggaaa aactattgaa gacgaatctg
     1561 accgttttat caaatatcat tgaacaggca ataataaata acgttgattt tgttttactt
     1621 gcaggagata attttcatca aaatcgtcct tcattaaaaa tacagaaaca tttttcagaa
     1681 cagatgaaac ggttagaaaa gaaccatata cctgtattta taatattcgg aaatcatgat
     1741 ttctatcaaa aagagcggta ttggttctcc tttcctaaaa atgtccattt atttacatcc
     1801 gaaacggtag agacaaaaaa aataacgata aaaagtggag aaactgtctc tctcagtgga
     1861 tttagttatc gtcaaccgtg gattcaaaaa gacaaagtga tggaatttcc ttctagagaa
     1921 ctcacagatt accatattgg gttgtaccac ggggaacctg gcgtctctca aaaaggaaac
     1981 tatgctcctt tccaaccctc aaagatgcaa gaaaagggat acgattattg ggctttaggg
     2041 catatccatg tgccaacggt cttaaatgaa aagcaaacaa ttgtttatcc aggtgcgcct
     2101 caaggtcata ctaaaaagga acaagcttct acatctattc tactagttga attaagtaaa
     2161 ggaagttgcc aaatacatcc gattaaagta gcagaggtct attggaagac aaaggaaata
     2221 tcattgagga aagcaagaac gacaaaagag gtcattgttc acattcgtca gcagctttca
     2281 aaagtagagg atggatttag tttaattgag ataaaattaa aagattatga ccatctcaat
     2341 acagatgttt tggaacggat acaatcagga gagctattag actatttgtt agaggaattc
     2401 tcagatagga taaatgattt ctttatttgg cgtatttctc tcatagagaa tactttttat
     2461 acgaagaccc cacttgctgc ttctgctaaa ttgatggaac agttatttca atactatcag
     2521 acacctcaag atttccaaca aattttaaat gaagtatata gtcatcaaga agcggctaga
     2581 atattgagcg aactgccgga atatcaagaa gaaacacttg aaaaagccaa gcagctgctt
     2641 aatcaagatt ttttatttga ggaggatcag gaatgaagat tttaaggatc gagattgctg
     2701 cttttggaaa atggcgtcaa aaaagttttg acttttattc aggcaatcag ctgatctatg
     2761 ggggaaacga agcaggaaaa tcaacgattt atcaatttat tcaagcaata ttatttggtt
     2821 tcccttcaaa aggccgtaaa aaaaaggatt atacaccaaa agacggctca gcctatggcg
     2881 gcaaaatatg gcttaaacat cctgtatatg gtgaatttgc tgtcgagcgc tacaagcagc
     2941 aaaatcgcgg aaaatcgaag gtgtggctgg gggatcaagt gggaagtgat gagttactag
     3001 aaaaactgat cgcacctttg acgaaagagt tattccagca ggtatttact ttccagcaag
     3061 agcagttgat ggaactagat catttgagag aaaaagagct acatgatgcg ctgatttctt
     3121 taggcatcac gggcagttct caagtattcc aaaagcggca agaatattat cagaaagcac
     3181 aacaattatt caagaaaaaa ggccaaaaat tactaatcaa tcaaaaatta aatgaatgga
     3241 aagagctgca agaaaaaatt catcaaaaac aagaacagga agcttatttt ggcaagttga
     3301 tccaacaaga acaggaatac gagtcgcaac agcagcagtt attggcacaa ttaaaagagg
     3361 cgaacaaaca attttcatta gccagacagc aagaacttaa tttttcttta tatgaagaat
     3421 ggcaatctct caaaaaaaac agcactacag gtcttcctga tgagcaactt cttttagatc
     3481 tggagtcttt ctccaaacgg tatcagcaaa caaatgagcg tttggaagaa ttagaagcaa
     3541 cactggaaaa gcatagcggg atggatcagc agtcagccag atattatttt tatttagagc
     3601 aggagcagga actaaaagat ctccagcaac ttcaatttac agcggaacaa ttaaacgaag
     3661 aatggcaaag attacaaatt gagactagag aaacaaattc agaattgaag attttggaac
     3721 aaaggtggca ttggcagaaa aatccgttac cggaagaatt tttatatgaa gaagaatgga
     3781 agcatcttct ggctgaagaa agaaggattg ctgatctaga aagccagatt tctgtgcgtc
     3841 tccaaatagc taaagaacag caagagatga ttgaagcaga agtgaatgac ttggaagaga
     3901 cctatccagc attattacaa aatcagtcag agatagcacc agtctcttca tctaaaccgt
     3961 atatgctgat ggctggcgga gcaataatca ttgcaggtat atttgtacca atgcccttga
     4021 aagtgatcct tttactaatt ggtgcaggca tgattggcta tttcttctac aaaaggcaac
     4081 caaaaattaa aactaaaaat gatttctctg agataaaagg aatgtggcaa gaaaaactag
     4141 gacaacttga tctagcctta gctcaattag ctgaagcaga agaaaaacaa aagagaactg
     4201 gagaagaaaa acagattctt cagcaagaag tatatcgttt tgcggatcat cggcacttag
     4261 gaaagatgga tacgctcaaa ctcatgaaag aatatggaca ggaagtcata gattatcaga
     4321 aattatatgg cgtatttgag cggaaacata aaagagaaca ggaaatacaa gaaaaactac
     4381 gacaaatcga ccaaaaattt gagtttgtta aagaatggtt accgatacaa gataagacaa
     4441 tttcagaaaa aatggtattg ctttcccgtt ttatacaaga gatggaacag atgaaatttg
     4501 ccagaagcta tcagcaaaat actttattga agcaagaaat caatcaattg aaaaagaaac
     4561 aaaaagtatg gatacaagaa tacagcgaac aattgactca agcaggctta tcttatcctt
     4621 cggaagtacc tgtcttttta caaaaagcca aacaagccga acagcagatg aaaagataca
     4681 atgaattatc ggaaatgctt actccactat ttcctgaaga gctgacaaaa gagaaattat
     4741 ctgtaagact gcgccaactg aaagaaaagc aatcccaact ccagcaagaa gaaaaagaag
     4801 caagtgaaaa tcggcaacga ctccaacttc aagtagaaga gttgcaaaga gacggcacat
     4861 tggacgaact ttatcaacaa gctagccggc aaaaagcaaa attacaggaa ttactggagg
     4921 aatggggagc acttgaaatc gccgggacat tcttaggtga tctttcaaca gagatgagtg
     4981 aaagacaatt accccagttg ttaagagcag caggtgatta tttaggtatt ttaacaaaag
     5041 gaaattatca gaagatatta ctgaaaaatg atacactgac tttaacagac ggatatacag
     5101 aatttcccat ctatgagtta tctacaggta cgaaagatca gctgattatg gcgatgagat
     5161 ttgcttacct ctcattagaa gctaaccgtt cgatatgccc gatcatcatt gatgatggct
     5221 ggcttcatta tgatcatcag cgaaagtatc aattagctga acttttagct aaatttggag
     5281 aaaagtatca aataatttgt ttttcttctg ataaagaaat ggtaagctat taccatgaga
     5341 tgaaccaaat cgtaaaacaa ttagaaggag caaataatga aaaaaattcg tgatttagta
     5401 atcgatgagc agtttgaaca atttgtcctg atcaaaagtg cagatgtaag aatcgctaaa
     5461 aacggaaaaa aatttattgc ttttactttc caagatactt caggtactat cgatggtaaa
     5521 tactgggatg cttcggagga ggaaatcaat aaatttacag ccggcacagt cgtttttcta
     5581 aacggtaaaa gagaggttta tcaaggaaac cctcaagtaa agattcttca tatgcgctta
     5641 acaagggtag atgagccagg agagcctagt ttatacatgg aaagagcccc tttgaagaaa
     5701 gaagaaatgg aagaagaaat caatcaattg ttgtttgaga tcaccaatgc gcattggaat
     5761 cgtattgttc gctatctact taataaatat caaaaacaat tttttgagtt tccggcagca
     5821 aaaagaaacc atcatgcatt tgccagtgga ttagcttatc atactttgac aatgcttcac
     5881 ttagggaaat caatcgccga tgaatatcct gagctgaatc gagcattgtt gtatgctggt
     5941 atcattttgc atgatttagg aaaggtgatt gaactttccg gtcctatgtc gacagaatat
     6001 acgcttgcag gaaatttgat cggtcatctg gtattgattg acgaagaaat aactaaagcc
     6061 tgtcttgcgt tgaaaatcag cgaagctgac gaagatgttc tcgtattacg tcatatggtt
     6121 ttagcacacc atggcttatt agaatatggc tcacctgtac gtccaagaat aatggaagca
     6181 gaaatattac atcaaatcga caatatcgat gcttcgatgc agatgatgtt gacttcgatt
     6241 cgtcaaacag aaccaggaaa atacaccgat cggattttcg gtatggacaa ccgaagtttc
     6301 tatgtaccaa aagatttata gcaaaaattt atttttttca ttcaaaacaa aaaaagcgag
     6361 acataagtct tcgctttttt tgttttcttt tattttgatg aatcagttgt ttcttcagtt
     6421 gaagattctt ttgttgaatc agttgatttt gtgtcagaac tctttgttga agctgtagtt
     6481 tcacttgagt ctttcgtact tgatgaagtt gttgtgaatg cactcaacac attttcaaag
     6541 gcatcatctt tgatttttac atttgcatct tttaattctt caccgattac tttagttgtg
     6601 aatgcattgt cacttagttt agtttcagta gcgatatctt ttagttgatc tttgtattta
     6661 tccatgtcat tgcctttatt ttggtttttc accattttga caacgtagta ttctgtcgca
     6721 taagaagtag gatttgttgt agtaataaca tcggagatct caccgtcttt caatttgaaa
     6781 gctgcttctt ttacttctgc aggaatagtt gttgtcgttg agtcgaattt aactttaccg
     6841 ccatcttctt ttgtctctgt atcagttgat ttgtctttgg ctaatttaga gaaatcatct
     6901 ccatcatccg ctgatttttt cacatctttt gcttcatctt cacttgataa tttgatgatt
     6961 tgtgcttcta cttctggatg gaaagatttc caagcagttt tcaaatcgtc atctgtaata
     7021 tctacgtgag ctttcaagcc agcttcaaaa gctaaattgt tacgaatata ttctttataa
     7081 gtatctttcg tatatccagc agcttctaat tgtgattcaa aagtatcacc taatgatttc
     7141 gcttgtttgt cgtattctgc atccacttgc ttatcggtta ctttatcgcc atatttgtta
     7201 ttgaatactt tataaatgat catccgttgt actaaggatt ggttcgatga ttcaagtttt
     7261 gcttcatcat agaaatcaga tacagtgatc gttccgcctt tcatcgttgc gatatcttta
     7321 ttagtatcgc ctgaacaagc tgctagagtt aaaacagcca acgcactagt agctgccaaa
     7381 ataattgatt tttttttcat taaaatttgc actcctgtaa ttagttatta tttttatata
     7441 ttaactatac catatcccat ttcctttaaa aacgttgtcg tggtagtttc aaacaaaatt
     7501 caaaatttca tcacattcct aggaaatacg caaacttttc tcacttatat agttaaatct
     7561 gttgagaaaa taatcattat tatatttgtt caggatactc tggcagatca gcttttagtt
     7621 tttctacttg ttcattgatt tgtgtgatac gtggttcggc ttggaattta aaatcttcga
     7681 tatctttttt gattgcttct tggaaagcag gaatcacaga ttcagctgtt tcttttgttt
     7741 cgatcaatgc gcttttaaaa tgattcaggc tgttatttaa atcatttgtc agagttgttg
     7801 cttcttccaa ttcttcgatc agtttctttc ttgtttcatt cccgctcctg ggcgccaata
     7861 acagacctcc gacagtgcca gcagcagctc caaataacag tcctttgaaa aagtttttaa
     7921 tcatcgcagg acacctgctt tacgattgtt tcttgaatag cttttagttc ttccgatcca
     7981 taactatctt gatgattgac aaagtgaata gaaaaatcat cctctttgct gtagcgaggg
     8041 actaaatgga tatgtgaatg aaaaacagat tgataggcta gttcacggtt gttattcaag
     8101 atattaagac ctttcatttc tggaaaagct ttttccaatg cttgagcaat cttaggcaca
     8161 cgcgaaaaaa cctctcctgc aagttcggga tcatattcaa aaatatctgc tacatgacgt
     8221 ttaggcacaa ctaatgtgtg tcctttcgtt gcttgagaga tgtctaaaaa agcatagacc
     8281 ttgtcgtctt catatatttt atagcttggg atttcttgat tgatgatttt gcaaaaaata
     8341 cagttttcca tataaaacat cctttctata aagaataaat acttcagctt aactttacca
     8401 taagttaaag ctattgtaag gaaaaaaaca aaataccgtc attttcttcg tggtataata
     8461 aataaaaata aatggcggag gaaaaagaat gagtttaatt atcgatcatg tcacaggggg
     8521 gtacggacat ctccctgtgt taaaagatat cagtttcgat gtacagcctg gagagatagt
     8581 agggttgatt ggactgaacg gagcagggaa aagtacgacc atcaagcaca ttatcggtct
     8641 gctggaagct tcaaaaggaa cgatagaaat caatcatcta tccttaaaga aaaatacgga
     8701 agaatatcgc aaacaaattg ggtatattcc agagactcct tctttatatg aagaattgac
     8761 attgagagaa catatcgaag tcactgcgat ggcctacgat atacctatgg atatagcaat
     8821 gaaaagagca gaaaagttgt tggagacttt tcggttatct aatcgtcttg actggttccc
     8881 agctaatttt tcaaagggaa tgaaacagaa agtgatgatc ttatgcgcct ttttgatcga
     8941 gccttcttta tatatcatcg acgaaccatt tttaggcttg gatccactag ctatcaatgc
     9001 attgcttgaa ttgatggtag aaatgaaaaa agaaggagcc ggtattttga tgtctacgca
     9061 tattttagct actgcagaaa aatattgtga tcgttttgtg gtcttacata acggagagat
     9121 acgagcagac ggttctcttg agatgttgag aaaagaattt cagctgccgg attcttcttt
     9181 ggacgaaatc tatattgctt taacaaagga gcaggcacat gagtagtttt tttcaaaaac
     9241 gtttagcaag acatcaaaag aaaatgatga aatatatgcg ttatgtattg aacgatcatt
     9301 ttgttttagt ttgtcttttc ttgattggcg gtgtgggatt atattattct aattggttga
     9361 aaaccctgca gccaccgttt gcaattggag ggctcataat ctctgtattt tggatgctct
     9421 gtttattcgt gggtaagatg gctacttttg cagaggcagc agatattgtt tttttacttc
     9481 ctaaagaaaa agaaatgcaa acctatttgg aacgagcttt tcgctattct tgcatttttc
     9541 cgttgatctt tttgatattg gcatgcggat tggccatgcc attagtggtg gttagtacgg
     9601 agcaatcctt ttcgatgttt ttcgtctatc tgatcatatt atggagtttg aaattcagtc
     9661 atctgcaaat caagagagca gaattgtttc gactagatca acaagttatt cgttattgga
     9721 aattaggctg gtttttttct tctctgatct ttttgtttct atcattttat tggctaatat
     9781 gggcaggaat agcaggtgca ttagtacagg caagtctata ttactggttt ttgtggaagc
     9841 aacaagaaaa aggattggat tgggagaaaa tggtgcatgt agaagaacat aggttgcatc
     9901 agatctatca atttatcaat ttattcacag atgttcctga aattacggca aagatcaaaa
     9961 gaagacgcta tttggatcct atattgactc atattaaaag agaatcaaaa aacacttatc
    10021 tttacttgtt tgcaagaaga ttggcaagag gttctgattt tagtggtctt tatttccgat
    10081 tagtaattat aggtgggtta ttgattgccg gagtagtcga cttttatttt agtctgatta
    10141 tcggtttctt atttttatat ttgatcggtt tccaactgtt acctttagcg aaccagttcc
    10201 gctatatggt tctcgttcag ctttatccaa tccataagaa tcagaagaag caggcgattc
    10261 agtatctact cacatgggta ttaattatcg cgtcggttat ttttggtttg attgctgcag
    10321 tcgtattaga tgggcagcag cgatgggttc cgctagcggc ttatttgatt gttactatgc
    10381 tctttgttaa actatatgta ccaactcgtt tgaagaagat gtcagactga aaacaaagct
    10441 gtgtagggta aaaatgagaa tgaaaaatag agcgttgaca gtaagaatgc tgttcgttct
    10501 attttttttg agaaaagctg gttttttgaa tggcaattaa atgaaaaaga acgtatatgt
    10561 gcttgacgtg tagtgttcag gcgactagaa taataagtac tgcaaaacaa agagtaagag
    10621 gacgggagaa tgcatgatgg agtttcagtt agaccaagag tggcggttac gtcccatcaa
    10681 aggcgacaca ggaaaaacat acataggcat gcgtgatgag gacaaagtct ttattaaacg
    10741 aaacacgact ccgatgttgg ctgctctttc aagggaagga attacaccaa aacttgtttg
    10801 gacaaaacga acggggaatg gcgatacttt gacagcacaa gagtggctgg aaggtcgctt
    10861 gctgactcct aatgagattg gtcaaagaaa cgacgtgatt gatgttttgt accatttaca
    10921 tcattcaaat tctcttaaaa ccatgctgac ccgtatcggt ggtcgtgtca tgacgccgga
    10981 gaagatgctg caaaaatatg aaaaagaatt accggaagaa ctccagaaaa atcaatttct
    11041 gcaaattgtc catcgttttc ttcgtgagca gatcccgtca atagataagg aaaacttatc
    11101 agtagtacac ggagatgtaa accatcgtaa ttggttagta tgtaaaaatt atttatatct
    11161 agtcgattgg gattcaatca tgtttgcaga ccctgcggtg gatattgcaa cgattttagg
    11221 aaattatgtg ccactgtcta gctggaatca gtggctgatc agttatggca tacgcccgac
    11281 tgacgaaatg cttgaaaaat ttcattggta tgcggccatg aatttgctcc aagaaatcac
    11341 cagatattgc aaacgtgaag atcatcgacg gatgaacgaa gaaattttac aattaaaacg
    11401 aattttcagt ggctgaggtt tggcccaaac tctgcggaga tttggccaga cctttttaat
    11461 tagaggaaag gaatggagat aaataatgcg tgtccgaaat cgtccgggag cagcggaaat
    11521 gttagcggct cacccgaatt ttgtaattag tgatccaaca ttgtggaagg gaaaatggaa
    11581 tgaattgttt gaaaacgatc atccaatcca cattgagatt ggtatgggga aaggccagtt
    11641 catcactgga atggcaaaag cccatcctga aatcaattat attggagtag aaatgcaggt
    11701 cagtgttgtt tcgattgcac tagacaagtt gatcgaacaa ccgcttccta acctgaaact
    11761 tctacatgtg gatggatcag cgttgacaga gtatttcgct gacagcgaag tagatcaaat
    11821 ctatctgaat ttttccgatc catggccaaa aaaacgtcat gaaaaacggc gattgacata
    11881 taagactttt cttgctgtag atgaacagat tcttcgtcca aatggagaaa tccatttcaa
    11941 aacagataat caaggattgt ttgagtattc tctggcaagt ttttctcaat atggcatgat
    12001 cctcaaacag gtatggttag atttacatca aagtcaattt gaaggcaata ttatgacgga
    12061 gtatgaagaa aaattttctt caaaaggtca acgtatttat cgagtagaag ctcaatttca
    12121 agataagacc aaaaagaaaa gtctgtgaaa ctaactttct gctttcataa aaacattaat
    12181 atccataaat aaatcccaga aaatgaacat tacagatgta atgtattttc tgggatttat
    12241 ttgatttaaa atgtatttat ttcatcggtt tttccacaag gtggaatcaa ttggaagcga
    12301 gaaaatgaaa ataatccttt gtcggtgatc ttcaattcgg gtatgacaga taatgttaag
    12361 aaagaaagtg tcaaaaaagg atcaaaggtt ttagctgctc ctagttgatg tgctttagtt
    12421 attaattcat tcaactgttc atagacgatc gaaaaaggtt cctgtgtcat gattccgcct
    12481 ataggaagag aaacacaagc tatttcctgc tgtttgttga caacggtcat cccgccacct
    12541 ttttgaatca aaagattagc agcatacagc atatcctcgt cgtttgtccc aacgacaact
    12601 agattatgcg agtcatgggc aatcgttgtc gctatcgctc cttgtttcag ctgaaatcct
    12661 ttcactatgc ctaatccaat gtttcccgtt tgatggtgac gctcgatcac cgcaatcttt
    12721 aattggtctt tttcgattga aggaatgaat cgttcgcctt gtcggtccac tttttctacc
    12781 aaatctttag tcactagact attcgggata atttcgatca catgggcttg tgaagaagaa
    12841 agaagcagct ctaacgaatg tggatttaat ggttgagcgt ttagttttgg cagacaacac
    12901 gtatatgaat ttgaatgatc agcaaataaa tggtcttgga gttgcccaga ttgaacaact
    12961 aatgttccct tatagaaaac ttcatgaatt ggcagcttgg taagatcgtc tgttaagaag
    13021 aaatcagctt gatacccagg ggcaatcgca cctagtgttt tcaaatcaaa acattctgct
    13081 gcattcaatg ttgccatctg aatggcttgt aatggatcga ttccaagtgc aatagcttga
    13141 cggacgatat gatcgattga tccttctttt actaaatcat tgatcagttt atcatcggtg
    13201 acaaagaagc atcttcttga attttcaggt gtgatcgccg gtagtagcga tgccagatct
    13261 tttgcaacgg tcccttctcg aaccattaaa tacataccaa gatccaaatg ttctttagct
    13321 tcttttgcag ttgtagcttc atgatccgtc cgaatacctg ctgcaggata aacatttaac
    13381 tcttccatgc cgataccagc tgcatgcccg tcaatttttt tcttatgctg gtgcatcaat
    13441 tggatctttt ctaggatgtc tgtttcatta tttgctactg cttgatagtt catgacttca
    13501 gctaagccta aaacttcggg tttttgtaaa aaaggggcta atttttttgc atttaaattt
    13561 gcaccattgg tctcaaaagg ggttacaggt acacaagaag gtagcataaa aaagatattc
    13621 atgagtgttt gtcttgcatc ttctatcata aactcaagac ctgtactccc agcaatgttt
    13681 cctatttcat ggggatctgt cactacagta gtaactccat gaagcaagga tacttttgaa
    13741 aattcgcttg gtgataaaag tgagctttcg atatgcacat ggccatcgat gaatcctggc
    13801 actagatatt gcccattagc attatgtacg ctttttcctt cgtattcacc gattcctacg
    13861 atcattcctt cgcagattgc tacatctttt tccatgattt ctttcgtaaa gacgttgacg
    13921 atcttagcat gcttgatcac taggtcagca ggcttttttt tacttgctac ttcgatatat
    13981 ttccttaatg ttgtttccaa tggagtgcct cccaagataa atttttataa gtataacata
    14041 aattcggttt ttgccaatat ttttttgtaa attcatttta tttgaaacaa aaagatcaaa
    14101 aagacgtatg ttttttgtgg aggggagaat aatggaaata aaacgattat cggatcaaat
    14161 gataagtgaa agttttgcca aacatgccca agacgtatat atattgccag cttcagaagt
    14221 attttacatc tattttcgct atggaaaaaa acgaacattc tggaagaaag tctcttcggc
    14281 agatggacag caactgatct caagatttaa gtatttggga cagatggata tcggagaaaa
    14341 aagaaaagct cagttaggtg catttactta ttctttagaa aaacaggaag ttcgtctgcg
    14401 gttgtcttct gtaggagatt accttcaacg agagagttta gtgattcggc tattatacgg
    14461 tacttttgaa acaccccatc gttgctttag ttctcgagat tttgcaacta ttttacagaa
    14521 aaccgtcaga cgtggattat accttttcag cggaccagtc ggatcaggca agacttctct
    14581 aatgtatcgg ttggctttgg aagaaaaatt gcaagtgatt actatcgaag atcctgtaga
    14641 gatagaagaa ccgttttttc tgcagctaca gatcaatccg aaaatagcac agacttatga
    14701 tacacttttg agactcgcat tacggcatcg tccagacttg ctaatcattg gcgagataag
    14761 agatgaatca actgcacatg ctgcggtaag agcagcacta acagggcacc gggtttttgc
    14821 aaccgtacat gcacgcaatc ttgaaggtac attggtcaga atccatgaac tgacaaagaa
    14881 aaaagaagag ctatctgaat gtttagctgg tgtcatttat caagaacttt tggaagatgc
    14941 caatcaccat ccttctgttt tatggagtta tcaatttatg gaggaagaat cagtaaaaaa
    15001 atcatgggag gaaagttatg aagaagctca ggaaaatatt tggcagtcag aactattcta
    15061 aaggattaac aagaagccag caaaaccagt ttgcacaaac catgggagaa ctgcttttat
    15121 ctggttttag tctgcaagaa tccctttatt tattactcac gatccgttcg tttccacctg
    15181 ttattttggc aaatatccaa catcagctaa aggaagggca agcgtttagt gaggtacttt
    15241 cgcaaatagg atatggagca gagcaactgg tacagatcga gttagctgaa cgtcatggga
    15301 atctgccgac aactttgttg gaaattgcca aacagtttcg gcttgttgaa ggatttcgca
    15361 atgatttgaa aaagctgctt gcatatccga tgctattgct cacctttttg ctaggtatct
    15421 tgtttagtat gcggttgttc gttttgcctc agcttattgg ttcaggaatg gtcatgcaag
    15481 agcattgggg tattcagctg atacaagtct ttcattggta tgttctacta ttcatcctag
    15541 cggttactct attggcttta ctagtaaggt atcgtctgat gaagttgtct cctgttgatc
    15601 agagtgaatg gataagcaga caattattga ttggaccgat atattccttg tatcaatcgg
    15661 cttatttgtc actagagatt ggaaagcttt ttcatgaagg tttcgaatta aggcaaatca
    15721 tagtctgctt aaaggaaacg aaacaagaaa gtctgattca gcatcttgcc tctaagttga
    15781 ttcaaggatt ggaggcaggt atgtcattgg ctgagcagtt ccagaattat cgttttctat
    15841 cagaagaatt cagtaaaatt gttttacagg gagaggcaaa gggaagttta ggtaaagaac
    15901 tgatttttta cagcgaatgg acaagaaaac agcttttcaa acgtcttcat cactggatgc
    15961 attttattca gccaatcatt tttttgggcg tagcggcttt gattttatta gtttatgccg
    16021 ctgttttatt acctgtttac ggaagcatag aggaggtttt gccatgaaaa agagaaaaat
    16081 atcttattat agcggtttta cattgatcga aatgctaatc gtcttactga tcatcagtgt
    16141 attagtgttg ttgttcgtcc ctaatttgtc gcgttatagg aatcatgtag accaagaaag
    16201 tcgtgaagcg atcatccagt tggtagacac acaaaaagag ctctatgcgc ttcaaaataa
    16261 tggaagagtt cctactgtgg aggaattgtt gaatgaaggc tatatcaaac gagaacatgc
    16321 agaaatctat cagcggcctt gaaggtaagg ttttagcatc aggatatacg ttgtttgaat
    16381 cactcttact gattttatta cttacaacga tcctttcttt tccagttctc gcattttctg
    16441 catggaagaa tgaattggca gtctatcaat ttttcggcca atttgaaaaa cgaatctatt
    16501 ctacgcaaaa aatcgctatt gtgaatcaga tccaaacagg cttttattgg aatagtgaag
    16561 agaatcaaat catttttcat gttccgaatc cagataaaat aaattgggaa gtattagata
    16621 ttcctgatga gattaccttg aaacgccatg cttctattac ttttgctgct agaaccggga
    16681 atgaaagttc actaaaagct tatcaatttt attgggaaga aaaagagcgg acgattacgt
    16741 atcaattcca gatagggagt ggtcgctata caaaaagaat tgaataaaac aggatttgtt
    16801 ttgttggagt cccttacagc gcttatgatc gcttctgtct gtgtctactt agtgagcttt
    16861 ggccagctgt ttttgcttca ggcagaaaag aaaagtgggg aggaactgct atttattcga
    16921 atgatttatg aagatatcaa gacgcagcgg atgtatcaca aaagaccaga gcgaagggaa
    16981 gaaatgatcc catacgatat ccaaattgtc gataataatg gagtaatcga aaaagtgttt
    17041 gtcaatatgg agaaagaagc gatcagtatt gaaaaaacaa gtaattccag catttacgct
    17101 gattgaatgt ctaattggac tgatgatatt gagcagtcta ttgctcacat tcaatctttt
    17161 gattcagcaa accatccaag taagtgaatt tttgcagcgt aaagatcaaa aagagtggct
    17221 aatattttta gcacaattag aagaagaact caagagcagt cacaatgtct ctgtgaaaaa
    17281 tcagcaactg cactacacga tcgaggataa acagtatatc atcgaaagat atcaggcaat
    17341 gatacgtaaa agaagaactt ccggcggaca tcaacctatg ttaacaagta tcactgagct
    17401 tcaattattg gaaaaagaac acacaatttc tttttatgta cactttgaaa atggagaaga
    17461 tggatatgcc atatggacaa aaaacgatca gtagaaaatg ttataagggc tctattttat
    17521 tttctgtctt gcttttattt cttttatgta cgtttttatt gatggcagca ttagaaagct
    17581 accgtttgtc aatggatctt aatatacgaa tcaaaaatta ttatatagca aaaataatga
    17641 agcagatggc tttatcggaa cagtctacgc ttgccgaaag ttcggaagga gttttttact
    17701 acacaactgg atctgtaaca tatcagtggg tacaacagtc cctattctta gaggtggaag
    17761 tctcaccgtt tatctttcgg ttcacagaag aagtaaaaaa tgatacagat actagtacag
    17821 aatgatggaa tgttcgtgaa aacgccctct tttctgttat aacactgttt ttaataaaaa
    17881 aatgtttgcc gtttcacaaa taaaaaacag tgaaaacgat tgaaattttg tcaattgttc
    17941 gatagaatta aacaggtgaa aaaattgtta taatatatct agaaatgagg tgcaccatgt
    18001 taccagaaaa aatggaacaa gggtttaatc aaaacctgga agctattcag cttttacaga
    18061 atgcattggg aacttccttt ttagaagcct atgtcgaaaa tgcagaaaat ttaatagatg
    18121 attatcaagt acgtgtggtg gatggagtgc cgacaaaaga gacaacgcaa cggatcacag
    18181 ctctttatga agagttgaag aaactttctt tcgagccaga agaatggcgc agactgtctc
    18241 aattactttt attgaagggc agccagacag aacatttgca ggcgaaccat caactcactc
    18301 ctgatagtat cggtttttta tttgtttttc ttattgaaca actatacaca aataaaaaag
    18361 caccggttaa gattctggat attgcggcag gaatgggcaa cttgttatta acagttcttt
    18421 taaacctatc gaatgcgggg taccaaacag aaggaattgg tgtggatatt gatgatacat
    18481 tgttggctgt cgcagcttct acaagtgatt tgacacaagc aaatgttcaa tactttcatc
    18541 aagacgggtt gcaggaatta ttaatagatc ctgtcgattt tgcaatcagc gatttgccaa
    18601 tcggttatta tccgaatgac gaaaaagcaa aagagttttt aacaagtacc gaagaaggcc
    18661 atagttatgc acatcattta ttgctagagc aatcaatgaa atatgtgaag ccggatggtt
    18721 ttggtttgtt tttgatgccg agtggatttt tagaaacgga tcaaagtgaa gaaatcaaaa
    18781 aatggtttaa agaagaaggt tatcttcaag gaatgattca attgccagat gaattgttcc
    18841 gtaataaaca atcgcaaaaa agtattttga tcttacagaa aaaaggacca caagcacaac
    18901 aagtaaaaga agtcttgctt gtgaaacttg cttcattaaa agaaccagag aaggtgacgg
    18961 aatttttcaa cgagtttaaa aactggaaat catctgctct gtaatcattc aacgagaagg
    19021 agagtcatat gtctaaaaca attgcaatca atgctgggag ttcaagtttg aaatggcaat
    19081 tatatcaaat gccagaagaa accgtagttg cgaaagggat cgtcgaacgt atcggtttac
    19141 aagattctat ttttaccatc aagtacggcg ataatcaaaa attcgaacaa atcatggata
    19201 tcgaaaacca cgaagtagca gtaaaaatgc tgttagatca gttgattgaa ctgcaaattt
    19261 taagctctta tgatgaaatc accggagtag ggcaccgtgt tgttcacgga ggagaaactt
    19321 atggggattc agtagtgatc gatgagaaag taatggaccg cattgctgaa ttagcagaat
    19381 ttgctccttt gcataatcct gcaaacttaa tggggatcaa agcgtttaaa aagattttac
    19441 ctgacatttt gagtgtggct gtattcgata catctttcca ctcaacaatg ccaaagcaaa
    19501 attatttata tagcttaccg gtgtcttatt atgaagattt caaagtaaga aaatatggct
    19561 tccatggcac aagtcatcgt tatgtgtcgg aacgtgcggc aaaattattg aacaaaccga
    19621 tcgaagaact aaaaatcatc acttgccact taggaaatgg tgtatcgatc acagcagtcg
    19681 atggaggtaa atccatggat acttctatgg gattcacacc attagctggg gtgacaatgg
    19741 gtacacgttc aggtgatatc gatccagctg ttctcccata tttaatggaa aaattagaga
    19801 ttgatattga tgaaatgatc aatgttttga acaagaaatc tggtctgcta ggcctaacag
    19861 gattgtctag tgatatgcgt gatcttgaaa agaactatga aaaagaacat attcgtttag
    19921 cttatgacat tttcgtggac cgcatccgaa aatacatcgg cggttatgtg acaacgatga
    19981 atggtgttga tgcaattgtc tttactgctg gtatcggcga gaatgacgga catgtacgta
    20041 gtgaaatcat caaaggtatg tcttggtttg gttgtgaaat cgatccagcg ttgaatgaat
    20101 tgcgtggtga agaagtagat atctctacaa aagaatcaaa agtaagagta ttagtgatcc
    20161 caacagatga ggaactaatg attgcccgtg atgtggagcg tctgcgcggc taagccaaag
    20221 cattcgttag gataaaagat gaaacgcatg caagagggaa ttcttgcatg tgtttttttt
    20281 gcggagaaga ccgcaaaatg gtaatttaac ttcaatttcc cttctttttt acaggatctt
    20341 cttagggaat tttgcttgga aaagtggtca aaagggaaaa gactggcatt ttatttattg
    20401 attttcagga aaatcccaat attttatttt cattcatctt tataagggac attacatatg
    20461 taaaaagaaa aaacattttt agatcagcct cgtgggctgt cgactttatt cttcgcttta
    20521 tgtttagcta gaaaaccgat ccgaaacatt cattgatcga ataataaaaa cttgattttc
    20581 cacctgtact ttgcctgaat cgtgaaagca caggtatgaa aatcaagttt tttgttgcga
    20641 aaaaacgtcc tagtcaatca gttggccgag cggctggcgg ctgatctgct cctgatcaat
    20701 aacgagtgct tcttggaagt gttgctgcaa aaagtagcgg tcatggctga ctgctaggag
    20761 cgttccttga tagtcttgca gcatttcttc aatttcttct cgagcatagc tgtcgaggtg
    20821 attggttggt tcatccaaaa tcaggacgtt gattttttct aaaaagagtt tcagcaacgc
    20881 caaacggatt ttttcaccac cggataaatc tttgatccgt ttacccacat cgctttgata
    20941 aaagccactt ttggctaatt gccgtcgagc gacttcttcg tttccagtca atgtgatggc
    21001 gtaagccagc aaacggctat cgggatcggc aaactgcagc tgctgcggca aataaccgat
    21061 ttgcaagcta ctacctaatt tgatggtgcc accgtaaggc ttttcctcac cgagtaataa
    21121 tttgagtaag gttgattttc ctgcaccatt gtcgccgatg atggctaaat gatctccacg
    21181 atagactgca aaactgctgt ctttgaatag tacttgatca gcgtactgct ggtgcaagtt
    21241 ttgaatgatg aaaacttctt tgccagattt tccaccatta gacaagcttt gcagccgatt
    21301 tttcggggga ggtggcggtt tgacgagtgt cagtttcgcc aggcggcgtt ccagttcttt
    21361 ggcttttttg aagaaggact cattgtctcc ttcatgtgcc cactgacgaa aacgacgaat
    21421 catgactttc aaccgctgga cttctttttg ctgcagttcg taattttttg tcagctcagc
    21481 caagcgagct tctttcaaga ctcgaaaacg gctgtagttt ccgggatact caatcaatgc
    21541 accttcttcc agttcccatg tttttgtggt gacttgatcg agaaattgcc gatcatgaga
    21601 aacgaccaga accgattttt ttgtattctg taaatagttt tccaaccagc gaatactgtt
    21661 aagatctaaa tgattggtcg gttcatcgag taaaagtaaa tcggcatcgg ctgctaaaat
    21721 tttggctaaa gcgactttaa ctcgttcgcc tccgctaagt tctgttaacc gtgcttcctg
    21781 acggtgtgga atccctaagc cttgcaagat cgctgcaatc cggtcttcta atacgtaacc
    21841 gcctagttct tcaaagcgat gctgcagctc accgtaacgg gccagacact tctctaagtt
    21901 tgtatctggt tctgtcatca atgcttcgta gcgactcatt tgctgtttga ggtcctgtat
    21961 ctcagcggca gaatggagca agtagtggtt gacggtcgct tcggaaactg taagttcttg
    22021 ttcgaccgtc ccgatcttta agcctttttt gcgactgata acaccgctgt cgacaccttc
    22081 tctgccggtc aagatttgta aaaaggttga tttgccagtt ccgttgatac cgactaaggc
    22141 aattttttca ccagcttcaa tttgacagga taaatcctca aataatggat tcccgccgat
    22201 tgttttttta atagaaattg cttgtatgat catgatctct ctccttgaga ccactcaaaa
    22261 aggccatggt tatccatggc ctgtgttatt taaactcaga ttatcatgag aaaaatacct
    22321 tgagatggcc attgatttta cgtgaattca actgttttgg acaaacttgt cccgtcaaca
    22381 gcaactgtaa aaccaattgc atggctaaat gcgatatggt atcgttggta attttcatta
    22441 cttgttattt tagtcatgcg catcatagta ttttccctcc ttcgtgtagt tgtcttttcc
    22501 agtgtacctg aaagtgtcag aaagttcaac tagcgctgac atttacttaa tatttatcga
    22561 tgtgtaattc tgtcagagag ctttttttat ctgactgagg gtaatgtctc gtggaccaca
    22621 tcattgtatt ctgagctaaa ccagcgttca ggcgaaatca tatggtgttt gataaaaaac
    22681 tttgtctaca tgacttcctt ttgccatttg cttaataccg ttgcattaaa cagctcttct
    22741 ctttggaaat ctcaccaaca tcgcgttcag gagtatcgtt gtggttgcaa tggcaagcgg
    22801 tagcctttca tcaattcttg aatgatttac cgaatgtagc acttgccttc tcgcggtacc
    22861 cgaacccgaa ataaaatttt agtttggcga taaaatcggt atccgccatc gatacttcat
    22921 attttttcgt atcagattca tcggaaactt ccacattgac gaaccaataa gctttggcat
    22981 gcttaggtcg ttttaaacca caccagggcg actaatcgcc ctggtgttca ctttttttta
    23041 ttttacttga actcattgac tgttttccct ttattttaaa cattataaag accgatgagt
    23101 gcttgccgcg tcttttgttt ttatcacggt tttttgtgca aaaaaacctg ccgatagttg
    23161 gcaggtcgtc tacgtgttaa gctttggtgt ggtctttagc tggcaattgg ttttctaaat
    23221 cagttcggac aacaagcaca tcgcaagctg cgtttctaat aacatattca gaaacagaac
    23281 caataaataa acgttctaca gcattcaatc ctgtggctcc taacataatc aaatctactt
    23341 gattatcttc tgggatttct ctggcaataa tttgttttgg tgagccatat tctacgacag
    23401 aggttacatt attcaagcca gctttcttcg cattgctttc ataatctgcc aatgtttgct
    23461 ttgccatttc agtagcttgt tctgcaagca ttccatcaaa ggatgaaacg gtttggaaag
    23521 aacgtgtgtc aatgacatgt gctaatagaa gttctccgtt atttcggata gctacattga
    23581 ccgccttttt aaaagctaat tcagcttcat cagaaccatc tacggcaacc atgatttttt
    23641 tgtattgttg taacataagc attcactcct caagtcaatc gtattgtact cttttattgt
    23701 agaacacttt agggaaaaag agaattattt actgctttgg ttcagcaatt ttttttgcaa
    23761 atcggatact gaaggtggca gaaacaataa ttacgatcag taaaaagacc aaggcaataa
    23821 agcgttgatt gaaaaaagct gttaaaatac ccattacgcc taaaacagca tatgcagctc
    23881 cgtaaaattg taggaatcct tgatttttat catttttgtt gatcaataca aaaaagatat
    23941 cctgtttatt aaataaataa tagctaacga ataataatac taaagtggcg ataatcatta
    24001 aaatcctaat catgaacaaa tcctccaaaa taagcaacaa atagaaaaag caatttgcca
    24061 agagcaaatt gctttattct ttaaaagatg gtaatctccg ttaatgccgt tgtttgtcct
    24121 gtagtattga tcccgcgaat tcaagcaggt gggtcccatg gtcgtagctt cgaactacca
    24181 aatgataagg catgttacca gcagtgacac aagacgggtc ccaagatatc aataaaaatg
    24241 ttcggtcaac acacaaagag gacaattcga acatcacaga tttcccacct ctatagtagc
    24301 atatgaattt aaaaagagca atgagagagc tcgcagaaac agaaccgttt tcttgtctag
    24361 ttttttggag gatgcttttt ccactctttt atacggtaat actgttgacc cagagcctgt
    24421 tcatatttcc ctgtatcttt tggctgataa tactgagcac tcttcagttt atctggtaaa
    24481 tattgctgat tgacccaagc ctgatcaaaa tgatgaggat actgataacc cacgccacgg
    24541 ttgagtgatt tcgcaccttt gtaatggcta tctctcaaat gatcaggaac atctccagct
    24601 ttgccctctc gaatatcagc aagtgctgca tctaatgcca tgtaggcaga attggatttt
    24661 ggcgacaagc aaagatcgac gacgacgtct gctagtggga tacgtgcctc aggcaatccc
    24721 aatttttcag cagctaatac agcgttcact gtacgagccg cagcagcagg attacctaaa
    24781 cctatatctt cataaccgat aaccatcaga cgccggcaaa tacttgccag atcacctgcc
    24841 tcaactaaac gggcgagata atgaagtgca gcatccacat cacttccacg aatcgatttt
    24901 tgaaaagccg aaataacgtc ataatgagca tctccatttt tgtcatgggt aagagctttt
    24961 ctttggacac attcttcaat gatcgacagt gtaagatgaa tccttccttc tttatctgaa
    25021 ggagtcgata gtgtagccag ttccagccca ttcaatgcac tccgcaaatc gccgttcgtt
    25081 gcacgcgaaa ggtgaagaag agcatcttcg tctaactgga ttgcttgttg tccaaggccg
    25141 cgttctttat cccttaaagc atgttcgact gccaactgga tgtcttgttc tgttaatggt
    25201 ttgacttcaa agatctgtgt acggctgcgg atcgctggat tgatggtaat ataaggattc
    25261 tcagtagtcg ctccgatcaa gatgattcgg ccactttcta aatgaggaag cagaaaatcc
    25321 tgttttgttt tatctaatcg gtgtacttca tccaataaga ggatcactgt accactcatt
    25381 tttgcttctt ccgctacaac ttgtagatcc ttttttgaat ctgtagcggc gtttagcatg
    25441 cgaaatgcat aattagtaga gccggcgatc gcacttgcga tactcgtttt tccagtacca
    25501 ggaggtccat atagaatcat ggaagagagc atgcgagcat cgaccatgcg gcgtatgatt
    25561 tttccttccc cgactagatg ctgctgacca acgacttcat cgatcgttcg aggtctcatg
    25621 cgataagcca atggctgttg cataggattt tcctccttct tgtttttacg tcccttaatt
    25681 atatcatatt tagcaagatg cctagaaaga acagccttct gttgttttgt tttcatagct
    25741 tatccaacta atattgtgta tgataaagta ggtgagaaaa atgacggata aacaaaagat
    25801 agatgaattt ttttggaata aaacgacgcc agaagtggca cgggatttat tggggatgta
    25861 tttggagcat gacacaccag aaggaagatt agctggatat attgtagacg cggaagcata
    25921 cctaggtcca gaagacgagg ccgcccatag ctatggttta agaagaacac cgcgtgtgcg
    25981 ggcaatgtat gaaaaaccag gtacgatcta cctttacacg atgcatactc atcggatttt
    26041 gaacatcatt actcagccag aagggattcc tcaaggagta atgatacgtg caatcgaacc
    26101 cgccgcaatg attgatcaaa tgagtaaaaa tcgtggcgga aaaactggtc cagatatcag
    26161 caacggtccg ggaaaattag tggaagcatt agcaattcct caagaacttt atggtcagtc
    26221 tatagcagat agttcgttac gcttagtttt tgagaaaaaa aagacaccaa aaaagatcaa
    26281 tgctttgcct agaatcggta tcccaaacaa aggtgtatgg acagaaaagc cgttgcgttt
    26341 tgttgtgtcg ggaaatcctt atatctcttt acaaagaaaa aaccaaatcg agaaagattg
    26401 gggttggagg aaagaaaatg aaaaagaagg atctattaac atatttagat gaaataattg
    26461 aaaaacaagt gacagactat gatgtagctt tagattggga tacaaaaaat catacgatcg
    26521 agatcgttgt tcgcttgttt gcagaaaata aagcacaatt tgagattgat gatgcagaag
    26581 ggatcgtttc gcaagaacca attatcgaat ttgaagacgg cgtacttctt tttaatcctc
    26641 agaaatctgt ttttgatgaa cgcaattatc tagcagtaat cccttatgaa ggaaaaaaag
    26701 ggttggcaaa atcagtagct gattctttag tggaatatct aaatgaagta ttagctcaag
    26761 ggcaaagcga tttgcttgat tttttggatg aagacgatga cgaagctgta ttcgagcttc
    26821 actgggataa tcagcaacta gcagaattag tagaagtaaa acagcaaaat gaagcagata
    26881 cttatttacc gtacccaagt tattaaggag tgacagatat gaaatggaat gaagtaaaag
    26941 tagaaactga aagtgaagca gtcgaagcag ttgctaatat tttgatggag gcaggggcga
    27001 gtggtgtcgc gattgaagat tctttagatg ttgaacattt tcagtcggat caatatggtg
    27061 agattttaga taaaaatgat tttacatcgc tgaaagaagg cgcactagtc atggcttatt
    27121 ttccggaaac gactttctta ccggaaatct tgccttttat caaagatcgt atcacacaat
    27181 tacctgagtt tggtctagct attggaaaaa ataaagtaac agttagtgaa gtagaggaaa
    27241 gcaactgggc aacagcctgg aagaaatact atcatccggt gcgtattacg cgaatgctga
    27301 cggttgcgcc aagctgggaa aactaccaga cagaagatcc tctagaaaaa attatcacac
    27361 tagatcctgg tatggcattt ggcacaggca ctcatcccac gacttccttg acattgacag
    27421 cactagaaac agtcttgcgt ggtggtgaaa cattgctaga tgtgggaact gggtcgggcg
    27481 tgctaagtat tgcagcaaaa tatcttggtg caaaagatgt ctatgccttt gatttagacg
    27541 aagtagccgt tcgttcggcg aaagaaaata tggatatgaa tgaaatagcc aaagatgtcc
    27601 atgtatcagc taacgatctt ttgacaggaa tcgagattga aagtgatgta atcgttgcga
    27661 acattttagc agatatcatc ttattgatga tcccagatgc ttggcgttta ctgaagcaaa
    27721 caggcacgct gatcgtttca ggaatcattg aagagaagaa gcaaatggtt ctggatgcca
    27781 tgttagaaca agggtttatc gtggatcaaa ttttccagca aaaagactgg tatgcaatta
    27841 ttttgaaaaa accagaggtg gaatagatgc agcggtattt tttaaaagaa tcatatgaat
    27901 caaaagacta ttttgtttta gaaggggaaa actatcacca cattgtacgg gttatgagga
    27961 tggaacccga ggatgaagtt tttttggcat tcaatgatca aatagccatt gttgcagaaa
    28021 tcacggagat tactgaagag gctgtttatc tgaaagaaat taaaaaagaa gaaaatcaaa
    28081 aggaactgcc aagttcgatt accatagcga gtggctatcc taaaggggaa aagctggatt
    28141 ggatcgttca gaaatccact gaattaggag cgcaagcttt tcttggtttc ccggcatcag
    28201 cctctgtcgt taaatgggat gcaaaaaaac gtatgaaacg acaacaacgg cttgaaaaga
    28261 ttgctcaaga ggcagcggaa caatcccatc ggcagatcgt gccatcagta gagttattgg
    28321 aaacgaaaca agatttattt gagcggctag atgattatga cgtggtcttg gttgcttatg
    28381 aggaatcagc aaagcaaggc gaaaaatcaa atgcagccaa aattcttagt gaaacaaaac
    28441 cagatagtcg aatcttagct gtctttggac cagaaggtgg attatcccgc gatgaagtcg
    28501 attattttgt agaacacaaa gggatacttt gtggattagg accaagaatc cttcgtacag
    28561 aaacagcacc tctttattta ttaagtgctg ctagctatca atgggaatta atgaatcctt
    28621 ctttcagcta acgttcttca ttaataaaag agtatcgaca gaaagaattg aaaaaatagt
    28681 caacaatttg tataatagaa acaattattt atacaatgga tacgaaaaat cgtttgaaaa
    28741 agcttttaaa aagcgaacat ttccgtaaaa aaacgtataa ctgcacggat tttgggacaa
    28801 ttatcaaaca gatatttgtc ccgattcccg ttttaccgaa aaaagaaagg gggatcgatt
    28861 cctgtgacaa aagaagaaat tttaacggga cccggtgtca taaagctcgt tagtcaatac
    28921 atgggtcccg aacatgtagc atttgttgag aaagcatgcg aatacgcgac tgctgcacat
    28981 gacggacagt ttagaaaatc aggcgaaccc tacattattc atcctatcca agtcgcaggt
    29041 atattagcag atttaaaaat ggatccccat acagtggcta caggcttctt acatgatgtt
    29101 gttgaagata cagaaatcac tttagaagat ctgagagaag aatttggcga tgacgttgct
    29161 atgttagtgg acggcgtaac caaattaggg aaaataaaat ataaatccca cgaagagcag
    29221 ctagcagaaa accaccgaaa gatgctgcta gcaatggctc aagatttacg agttatcatg
    29281 gtcaaattag ctgatagact acataacatg cgtacgttga agcacctgcg agaagataag
    29341 caaagaagga tcgctcagga aactttagaa atctatgcgc ctcttgcaca tcgtctaggg
    29401 atcagccgga tcaaatggga attagaagat acagcacttc gttatctaaa tccaaaacag
    29461 tattaccgta tcgtccactt gatgcagacg aagagagaag aacgtgaaaa atacgtaagt
    29521 ggtactgttg aagatattcg aatagcgaca gaagagctgg ggatttttgc agaaatctat
    29581 ggacggccaa aacacattta ttcaatctat cgtaaaatga aagatcagaa aaagcagttc
    29641 aacgaaattt atgacttgct agctattcga gtgatcgtag attcaatcaa ggattgttat
    29701 gctgtattag gagcaatcca cacaaaatgg aaaccaatgc ccggcagatt taaggattat
    29761 attgccatgc caaaagctaa tatgtaccaa tctttgcata ctaccgtgat cggtccggca
    29821 ggaaatccgg tagaaattca aatccgaaca caggaaatgc atgaaatcgc tgaattcggg
    29881 gttgctgcac actgggccta taaagaagga aaaaatgaaa aagtagaacc agatggtatg
    29941 acgaaacaat taagctggtt ccatgagata ctcgaacttc aagacgaaag ctatgatgct
    30001 tctgaattta tggaaggcgt aaaaggagat atctttagtg ataaagtcta cgtcttcaca
    30061 ccaaaaggag acgttactga gttaccaaaa ggatccggac cattggactt tgcatacagt
    30121 atccatacag atatcggtaa caaaaccact ggtgcaaaag taaatggcaa aatggtgcag
    30181 cttgattaca aattgaaaaa cggagatatc attgagatca tgacttctcc aaattcattt
    30241 ggcccaagtc gcgactggtt gaaattagtt gctactagca aagcaagaaa taagatcaaa
    30301 cgtttcttca aagcccaaga tcgagaagaa aatgtgatca aaggccacga atccgtggtc
    30361 aaatgtatta cagatctagg atttacgcct aaagatattt tgacgaagaa caaactgcaa
    30421 gaagcactcg atcgttttaa ttatcaaaca gaagatgatc tctatgcagc tgtagggtat
    30481 ggagaagtta gccccttgac gatggccaat cgtctgactg aaaaagaacg taaagaacaa
    30541 aaaatcgagc agcaaaagca agaagcagaa gaaatcatga atcagccgaa aaaagaacct
    30601 gacaaaatga aagtacgtca tgaaggtggc gttgtcattc aaggggtaga aaacttacta
    30661 attcgtatca gtcgctgctg taatccgatt cctggtgatg atatcgttgg ttatatcact
    30721 aaaggcagag ggatatccat tcatcgtcga gattgtccga atgttcagcc tgacaaacca
    30781 aatgtagcag aacgtttgat tgaagtcgaa tgggaagata catcgaatac acgaaaagag
    30841 tatgatgcag atttggaaat ttacggctat aatcgttcag gcttattgaa tgatgtactt
    30901 caaacagtca atgcgctaac gaaaaatctc aacagcgttg aagcacggac gaataaagat
    30961 aaaatggcga cgatccattt gacggttggt atccagaatt tatcccacct aaagagtatc
    31021 gtggataaaa tcaaagcagt acctgatgtc tacagtgtac gccggacgaa tggataggag
    31081 gacagatatg agagcagttg ttcaacgggt aagtaaagct gctgtgtcag tcgatcagca
    31141 agaaattgga aaaattggct acggcctact tgttttatta ggcattcatg aaaccgatac
    31201 gcaaaaagat gtggactatc tggtaaaaaa aattgcacaa atgcgtattt ttgaagatga
    31261 acaaggaaaa atgaatatta gtgtagaaga tgtgggagga caaattttaa gtatctctca
    31321 attcacactg tttgcggata cgaaaaaagg aaatcgacca agctttgtgg aagccgcacg
    31381 accagaaaca gctattcctt tatacgaatc attcaatgaa ggaatcagaa gtcgcggcat
    31441 cacagtcgct accggacaat tcggagcaga tatgtcggtt tctctcgtca atgatggacc
    31501 tgtaacgatc attattgatt ctaaaaacaa ataaagtaat ctggttttca ctagtaaaaa
    31561 ctatgaaaca cgtcgcttaa gttagactga taaactctaa cttaagtggc ttttttgtct
    31621 gcaaaaagcg cttcttttgt cagcagtcgg aaaaaaagtt aagcttaaat tatacaagtt
    31681 attttttata ggaggttgct gaagatgaaa gaagtaccag tagtagatat caaaatcaca
    31741 gatttaaaaa aattgtatca aaaaggatac aacatgttgg aggagttacg ccatgaagcg
    31801 gacgctcccg tcgtcaaagc aaagattttc aataaagaag ctatcacgat ctacggatca
    31861 tcagcagcaa aagtatttta tgatccaagg aatttcaaac gaaaaggtgc tatgccaaaa
    31921 ttagtattga agacactttt tggtcaaggt ggagtacaga ctttggatgg agctgctcat
    31981 caccatcgga aaaatatttt tatggatcta atgacaccgg aaagaatgga agattatcat
    32041 cgtatcttag ataagaatct gacacaagca cttgaagcac agcatggtca atttgaacta
    32101 tttgatttaa gtaagatggt tttctttaca tctatttgcg agtgggcagg tatcaattta
    32161 tcagcgattt ctaaagatga ggtcgaaaaa ttagcagaat atcaaatctc tatgatcagc
    32221 ggaacgttta cttctccgat tgatcacata aaaggtgtcg aaaatcgcaa aaaatcagaa
    32281 aaatgggcgc aaggcttgat tgaagaagct cgacaaaatc ctgtggctgg aaaagaaaat
    32341 gtggcattat atgcttttgc caatgccaca gatttagatg gtcagctttt acctctggaa
    32401 gtggcagctg ttgaattatt gaacatcatc cgtccaacgg ttgctctaac tgtgtgggcg
    32461 gcattgatgg gacatgcact tttcagtaga ccagatttgt atcagcaatt aaaaaatgac
    32521 ttttcgacgt tacaagatcc gtttattcaa gaaatgagac gctattatcc tttcttccca
    32581 atgctacctg cgatttcgct gaaagaagta gaagtagatg gttatcgtat accagaaggc
    32641 agttgggtta ttttagattt atatggaaca gaccatgatg aacgaacagt tgaagcgcca
    32701 gattccttta tgatcaaacg gtatgtaggg aaagcaaaag atatttccta taaagaagaa
    32761 tatgagatga ttgcacaagg cgggggaaat tttcgacaaa tgcatcgctg tgcaggagaa
    32821 tggatcactc ttcatagtct acgtgtgttt tccgatcagc tagtaaataa gtttgagttc
    32881 tctgtacctg aacaagattg gacgattcca ttcaatcagt ttccgactta tccgaatagc
    32941 cgagcgctac tttacaagaa ttagattagc ataaacttat cgaaaaaaag gaagatcaaa
    33001 cagtgctgat cttccttttt tcatattact ataaattgat aaggtcaatt gatcaaaatc
    33061 cacgaaatgc ttcatcaatg gtttgataat cttcattgga taaatgcaaa tctaaagctt
    33121 ggacattgtc agatacttgc tctggacgct tagctccagg tataactaca gacactcgtg
    33181 gattcttcat gtaccaagct aaaacaagtt gcgcaggagt ggcttggtat cttttagcaa
    33241 tggggcgaag tacatcgaca gcggttaaaa tttctctgaa acgttctcct tggaaatctg
    33301 gatttctttt tcgaggatct ccttcaccaa attgtttttc ctcaccaagt tcatattttc
    33361 ctgtcagcaa accggaagca agaggaaaat agggaacaaa actgattttg tttttttcaa
    33421 gataagggaa taattctttt tcagcctgcc gatggatcaa actgtattta tcttctacta
    33481 catcgacata tccatctgca ttcgcttctt tcaattgttc taacgtgaag tttgacacac
    33541 cgactgctcg gatttttcct gcttctttta attcgtgcaa tgtagcaact gattcatttt
    33601 ttggtgtgct ttcatccgga aagtggatat aaaaaatgtc gatgtaatca gtttgcagac
    33661 gttttagtgc atcttccacc gattgtttga gaaactcagg agaattatca aatgttcgcc
    33721 ctttatttgg tacatgagca gcttttgtag cgatgacgac acgtgagcga tcatattctt
    33781 tttccttcag tacctcgcca atcagttctt cggaacggcc gtttccgtaa gcataagcgg
    33841 tatcgatcaa attgatcccg ctattcaaag ctgtacgaac tacttgtttt cctgtctcat
    33901 cttccaaacc gtcaaaaaga ttatgtcctc caacggcatt tgctcctaat ccaagctgtt
    33961 ctgcgtagac ttgtgaatgt ccgattctta tttctgccat agctgattcc tcctttttgt
    34021 ctagtctaaa acaaaatacc aaaaagctga actaaaacgt ttttgtgagg ggaaatagtc
    34081 agatatctct tgactttgag actggttttt agtaggttat aagtaatatc gaatgtcaat
    34141 gaaagagcga gtaagttttt gaaactttac aagagaggat catcgaggct gaaaatgatc
    34201 taaagtttca ttagcctaaa gacactctgg agatggacga gtgaaaagcc gtcccgcgta
    34261 cgagcgttat tcgtaagagg aaagagaaat ctttcaaaat taggtggtac cgtgtatgaa
    34321 tttcattcac ccttgttcat gatgaacaag ggtgattttt ttatttacat agctaagaaa
    34381 gggagagaaa actatgagtt tccaaagacc aaaaggaaca aatgatattt tgccaggcga
    34441 atcagaaaaa tggcagtttg tcgaagaaac agcacgttta ttattcagag attatcagta
    34501 taatgaaatg cgtacaccga tttttgaaca ctatgaagtg atatcccgaa gtgtagggga
    34561 tacaacggat atcgtttcaa aagagatgta tgatttttat gacaaagggg aacgccatgt
    34621 gacgcttcga ccagaaggta cagcaccaat cgttcgttct tttgttgagc ataaattgtt
    34681 cggcccagag tatgcgaaac cgttcaaaac tttttatatg ggaccaatgt ttcgctacga
    34741 acgccctcaa aaaggacggt tacgtcaatt ccatcaaatc ggagtagaag catttggatc
    34801 agaaaaccct gcaactgatg tggagagcat ggtgatggca cttgatttct tcaaacagtt
    34861 ggggatcacg caaatccggc tagtcatcaa ttcattaggt gataaagaaa cgcgtcaagc
    34921 ctatcgtcaa gcattgatcg actatctttt accttttgaa tcagagctga gtgaagactc
    34981 taaacgccgc cttcatgaaa atccattacg cgtattggac agtaaagaca aacgagatca
    35041 aaaatttgtg gcagaagctc catctatctt agattatcta agcgagcctg ctcaaaaaca
    35101 ttttgatacc gttgtttcca tgctggatgc attggctgtt ccttatgaaa tcgacagtaa
    35161 tatggttcgc ggactagatt attacacaca tacgattttt gaaatcatga gtgacgcacc
    35221 aaaaatgggg gcacaagcaa cgatttgcgc aggcggacgt tatgacaatc tagtggaaga
    35281 actaggtggt ccttcaacac ctggcttcgg atttgcaatg ggtatcgagc gattactctt
    35341 gactatggag gcagaggaag tagttatccc tgcatttaat gagttggatg cttacgtggt
    35401 cgcactcgga gacgaaacaa atatcgaagc attgaaagtg gtccaagcga ttcgaaactt
    35461 tggtttttca gctgaccgcg acttcatgaa ccgtaaagca aaagcgcaat ttaagacagc
    35521 agataaagcg aatgccaaat tagtattggt gatcggtgaa gatgagcttg ctagtcaaac
    35581 gattaatgtc aaagcaatgg caagccgaaa agaaaaaagt tttccattag aagagatata
    35641 tgaacatttt gatgaagtct atgatgaaat gactttattc gagtaggagg aaaaaaataa
    35701 atggcacaaa gaacgatcta ttgcggatta gtttccgaac aacaattaga acaaacagtt
    35761 acattaaaag gatgggtaca aaaaagacga gaccttgggg gagtaatctt tatcgaccta
    35821 cgtgatcgtg aaggaatcgt tcaaatcgtc tttaatcctg aaatcaacaa agaagcatgg
    35881 gaaatcgcgg ataaatgtcg cagtgaatac gtgatcgaag tgactgggga agttagaaga
    35941 cgcggagaaa atgcagtaaa tcctaaaatg gccactggtg aattcgaagt gattgcaagt
    36001 gaaatcgtga ttttgaatca agcaaaaacc ccgccatttc aaattgaaga tgatcaagca
    36061 atcagtgacg aaatacgttt gaaatatcgt tatttggatc tgcgtcgtcc aaaaatgact
    36121 aaaaacatca aattaagaaa tgcgacaaca aaagcgattc gtcattattt agatgataat
    36181 gactttctcg atatcgaaac accttaccta gggaaatcta caccagaagg cgcaagagac
    36241 tacctagttc cttcacgtgt ccatgctgga catttctatg cgttgccgca atctcctcaa
    36301 ttgtttaaac aattgctgat gaatgctgga ttcgaccgtt attatcaaat cgttcgttgt
    36361 ttccgcgatg aagatttacg tggagaccgt cagcctgaat ttacgcaagt agatattgaa
    36421 acaacgttct taacagcaga agaaatccaa acttacacag agggattgat tgcgaaggta
    36481 atgaaagaag ttcgcggtat cgaagtcaca ttgccatttc ctcgtatgac ctatgatgaa
    36541 gcaatggctc gctacggcag cgacaaaccg gatacacgtt ttgatatgga attgatcgat
    36601 ctaagcgata cagtcaaaga agtagaattc aaagtcttcc aaatggctct tgaaaacggc
    36661 ggtgtcgtga aagcattgaa tgctaaaggc gctgcagatc gctactcacg aaaagacatg
    36721 gatcagttag gtcaatatgt aggacaattc ggagctaagg ggcttgcatg gctgaaagta
    36781 gaagaagacg gattgaaagg tccaattgct aaattcatgg gagaagcaac agaagcaatc
    36841 attaaagcaa cagatgcaaa accaggtgac ttgctgatgt ttggcgcaga taaaagtgaa
    36901 atcgtcgctg ctgcattagg tgctatccgg acacgtttag gaaaagaatt aggactaatt
    36961 gatgaatcga aattcaattt cttatgggta actgattggc cacaatttga attttcagaa
    37021 gaagaaggtc gatatgtctc tgctcaccat ccattcacga tgccaaaaga agaagatatc
    37081 ccgttattgg ctgaagaccc tgcaaaagtc tatgcagaag cttatgatat cgtcttgaac
    37141 ggttatgaac taggcggagg ttctatccgt attcatactc gtgagcttca agaaaaagta
    37201 ctagaaactc taggctttac aaaagaacaa atggaagaac aatttggttt cttgttaaca
    37261 gctttagatt acggattccc tccacatggc ggtattgcat taggattgga ccgttttgca
    37321 atgttattag ccggagaaga taatattcgt gaagtcattg cctttcctaa aaacggaaaa
    37381 gcagcagatg tgatgagtga tgcaccaagt atggtttcgc ctttacaatt gttcgaattg
    37441 aatattgatg taacgaatat agaagaatag ccgataaaaa ggtaaaaagg atttgtcgaa
    37501 tacgcttctt ttgacaacct tgatttaatt gaaaaacact ttataatgaa gccataacat
    37561 ataaagcggg gcttttccat gaaaaaaaca ttcgaaaatt gggcttatca tgattacacg
    37621 accaagcttt cggtatctat cgtttatgcg ttgatcgcat cagtcgcatt gaatttcttt
    37681 tatcagccag gacatattta ttcaagtggt attactggtc tagctcagat tttgacgact
    37741 ttgtcaaaat cactgatagg attcgaagta ccggtatcaa caactttgta tttactgaat
    37801 atacctttgt ttgtattggc gtggttaaaa atcgggaaga agtttacaat tttcactttt
    37861 atcacagtca ctttgacctc cctttgtatc catattttac cggaaacagt cctatctacc
    37921 gatccaatca tctgtgcgtt gtttgggggg gctgtgatgg gactaggtat tgggctagcg
    37981 ttgagaaacg gcctatcatc gggcggtcta gatatcgtga gtatcacgat tcgtaaaaaa
    38041 acaggaaagt cgattggttc tatttcgatc tacttcaatg cattgatcgt ttttgttgcc
    38101 ggaattctat ttggctggca atatatgttt tacagtacgt tgtctatttt cgtcagtgga
    38161 aaagtaactg atgtcgttta tactaaacaa aagaagatgc aggtaatgat cgtaacgaaa
    38221 catccagaaa aagtagtaaa tgaaatccaa aactgtatgc gtagagggat cacgatcatc
    38281 aatgaagcag aaggtgctta taagcatgat aagcagacag tattgatgac gatcgttaca
    38341 cgatacgaac tgcctctact tagagaagca atgaaagctt ctgatccaca agcttttgta
    38401 agtattgcag aaaacgtcca gatacttggt cgtttctatg aggatggcat ttagatcgag
    38461 tttgacaaaa attcatgaaa tactgctgta gacagacgtt cgtttgtctg cagttttttt
    38521 ctaccatagt agaatcagca aagaaaaact gcttttttat ttgaaatttt cttaaagttg
    38581 aaaaaaagca tgtttatttt tttaaattta tgggatgata gaaaaaaata gtagagaaag
    38641 gacacgattc tacttgctat tttcacttaa tacccgtata ttacgaatga aaaaagttta
    38701 tgaaaagttg gaatattgaa tggaaaaaca aaaaaggtta aaaaacagcc gctacatcac
    38761 tgggtttgat gggctccgtt cattagctgt ggtgggtgtt atcttctatc accttctgcc
    38821 aactagtatg aaaggcggct atttgggcgt tccgattttt ttcgtcgtat ctggttattt
    38881 gatcacggat ctgctgcggc aggaatggga acaaaatgga aaaatcaata tttggcaatt
    38941 ttatgtcaga agaatgaaga gactctatcc ggcacttgtt tttatgcttg tgacagcttc
    39001 ggcttatatc actttgtttc agcgagggct gttaaacaat cttcgaggag ttgtggtcag
    39061 cagcttactg tatgtcaaca actggtggca aatcaataac ggtttatctt atttcgatcg
    39121 atttgctaat gagtcaccgt ttacgcatat ctggtcttta gcagtagaag gtcaaaacta
    39181 tttggtttgg ccgatcttgt ttgtattgtt gatggtattt gttcgtaaaa gaaaatggat
    39241 cttttatact gtgttaggta catccttcct ctccgccatc ttgatgatga tcttgtatac
    39301 accaggaggc gatccaaccc gtgtttatta cggtaccgac actcgtctgt tttctatatg
    39361 gttgggaagt gcgcttgcgt ttgtttggcc aagtacgcgt ttaaagaaaa acatcccgaa
    39421 acaagcgaaa aatattctga atatcgctgg aggaatctcg cttttggcac tgattctttg
    39481 cttcttcttt ttagatgatc attacaattt catctattac ggaggaatgc tcctagtgag
    39541 tctgttatgc gtagtgctag ttgcagtgac agcacacccc ggagcaagtt tgaatcgatg
    39601 gctgacaaat ccagtattta cttggattgg caaacgaagc tatggcattt atctgtatca
    39661 gtttccagtt atgatttttt atgaagcaaa ggtgactgat attgccgatc atgttttgtt
    39721 gcatacttta gtggaaatca cattgattct aatcatcagt gaactttctt atcgatatgt
    39781 ggagcgtccg ctagcacgtt ttgattatgg tcgtacattc caagtgatga aaggatggtt
    39841 cagcaaaccg atcatcagta agagcaaacc atgggttgtt ccaggcacat tacttgtagc
    39901 aattgcactc gttggtttcg ttacggcacc gaaaaacgct gtaacagccg atcaaaaaca
    39961 actgcaggca aaaatcgctg aaagtaaaaa attagcagaa gaaaccagaa acaattcaga
    40021 aaacaccact agttcggttg accaagcgat ccttgataag tacgagttgt ccaaggcaca
    40081 agggaataag gcacaaaaat tagaactaac ggcatttggt gattcagtta tgttggatgc
    40141 tgcaacggat ctacaagaac tttatccaaa agtagtggta gatggagatg tcggacgaca
    40201 attatatgcc agtgtaccgt acattgaaaa attaaaggaa caagatttgt tgaaagacac
    40261 tgttctgatc ggactaggaa cgaatggctc attctcggaa gctcagtttg atagtgtgat
    40321 ggatgcaatc ggtgatcgaa aagtatactg ggtcaatgtc cgagtaccga cgaagcgctg
    40381 gcaaaatgac gtgaatgcga tgcttgaaca gatgacgaaa aaatacgaca atatgacgct
    40441 gattgattgg tacagctaca gtaatgacca tagtgactgg ttttatgatg atcaagtcca
    40501 tccaaatcct gaagggatga cacattacat tcacttagtc agcgaagcct tgctaggagg
    40561 aagttcaagt acgaacagca gtgagacaaa cgtgacagaa tgatagctac aaaaaacttc
    40621 aggcaaaaac atttgttttt gcctgaagtt tttttatatt taccgtgttt ttaacattca
    40681 tatagattca ggaagcaaaa cggttgagtg tgtctgtaaa taacgttctt tttgttttcg
    40741 ggtgagtttt ttgaatgcag cttctgcttt tgttgcttcg cttcttgaag aaaatacttc
    40801 tgcatggatc atcttaacag gtcttctttt ttgaagacga gtatatttag caccagtacc
    40861 attgttatgt tcctctaatc gtctagaaag atcggttgta tatccaccat aaaatgtctg
    40921 atctttacag aataatacgt aaaaataatg ttcatttgcc atagagcatc tcacgaatct
    40981 ctgcagtgta ttctccatcc atattgtaag tgatcaatgg tggagcgact ttgaatccgt
    41041 ctaatttgcc ttctttgatt ccttcaacta acaaaatatt tgcctctttt ccaggttttg
    41101 ggtaaacaaa ttggatcctt ttaggtgcaa ttcgatagtc ttccatgacc tgaatgattt
    41161 ctaagaaccg atcaggacga tggaccatag taaagcgtcc atttgttttt agtagcttac
    41221 ttgaaatatc gatcacttct tctaacgtcg tatgaatctc atgacgggcg attgccaggt
    41281 gtttattagg gttcgtttta tttgttggca gccctttgaa ataaggtgga ttacagacga
    41341 ctaagtcaca agaattatgt cgaacgacag ataagctgtc tttcagatcg atggtgtgga
    41401 cagtcatttg ttcatttaaa tggttaagcg cgatactacg tcttgccatg tctgctagac
    41461 gaggttgaag ttcgatagcg tcgatagccg cctgggttcg tttacttaaa aaaagtccaa
    41521 ctgcgccatt tcctgcacaa aggtcaacaa tcttcccttt tttaggtaca cgggaaaagt
    41581 gagcaagcag cacagcatct aaagaaaaag aaaacacttt ggaactttgg ataatcttga
    41641 tatcttctgc gtataattgg tcgattcgtt cgtcttcgtg aagcatggat tccctccaaa
    41701 atgaaaaaaa tagtcgtctg tattatacta tttttattaa aaagaaccaa ggtggcttgt
    41761 caaacctcta ttttttatgc atactatgac cataagaagg gaaaggaaga gactatgttt
    41821 tatcgattta tgcgcggggt agttcgagta ctattagcct tagttaatgg aaatgcccgc
    41881 tatgagaata aagaagtttt accgcaagat gagaattaca tactagttgc tccccatcgt
    41941 acttggtggg acccattata tctggcggta gctgcagcac ccaaggaatt cagctttatg
    42001 gcaaaagaag aactgttcaa aaatccagtt ctgcgattta tattaactcg atccaatgct
    42061 tttccagtta aaagagaaaa tccaggacca agcgtcatta aaacacctgt aaagattttg
    42121 aaatcgacaa atttgagttt gatcatgttt cccagtggga caagacatgc tacagaactt
    42181 aaaggcggaa tggcattgat ttccagaatg tctaaagcga aaatcgtgcc agctgtatat
    42241 caaggtccgt tgacacttgg ggatctgttc aagcgtcaga gagtgacagt gcgtttcggc
    42301 gaaccaatcg acttatcaga tatcaagaaa acggataaag aaggtatggc ggagatcgaa
    42361 cgacgaacac aagcagcttt tgacaaattg gacaaagaag tgaaccctga tttcaaatat
    42421 gaagtcaaaa aaaaataaaa tgataagttt atgcgtgggc ggtcttttga atctactgtc
    42481 ctgttcagtt cagacttttt caatgaaaac gagggagaga cgtcaagtct gccctctttt
    42541 tgcgttccaa tatgtaaaat agaagacagg tgtcatgtaa tggatcaaag tgttataata
    42601 attagaagga cattttttga ggtgattgaa tgcgtttttt acatacagcc gattggcata
    42661 tcggaaaaaa actacaaggt tatgacttga ttgaagacca gcgtcatgta ctatcttcta
    42721 tactagatat cgcgaaagaa gaaaaagtag aggcaatcgt gattgccgga gacttatatg
    42781 ataggagtgt cccagctgtt gatgccgtag aattatacaa tgaattgatg gtcgattgga
    42841 atttaaagga aaagatcccg atttttgcta tatcaggaaa tcacgatagc agtacgagac
    42901 tttcagcggg tacgccatgg ttcagttatt cgaactattt tttgcgaaca cagctagcag
    42961 aagcatttga accagtcgag tttaaaaacg tacaattttt ctttcttcct tactttgaac
    43021 caattgcagc gagattatat tttgaagatg acaatatccg aacgatcaag caagcggtag
    43081 ccaaggtgat agataaaatg caggagctat ttgattcaga aaaaaaacaa gtattgatta
    43141 gccatttttt tgtaatggga agtgtaaaat ctgattcgga aacgaaaatc gaagtaggcg
    43201 ggttggattc gatccctggt gaactactta caccgtttga ttatgtagca ctaggacatt
    43261 tgcataatca agctgctttg agacaggata atgctcgcta tagcggttcc ccattgaaat
    43321 tctctttatc tgagatcaac caaaaaaaag gcgtatggat cgttgacctg acaacaggcc
    43381 tggagttgaa ttttagggag atcgaacccc tgcatgatat tgaagaaata acagcgagtt
    43441 tcaaagaatt gctggatcct gccttttatc agtccgtcaa tcgggagaat tacatctata
    43501 tctatctcac tgatagaacg atcatcccga atatgatgaa ccagcttcgg caaatatatc
    43561 ctcgtatttt ggggattgaa cgggcaaacg gtcgagcaga acaaacaaag cgcaaacgaa
    43621 aagtactaga aatgaaagat cctcaaaaat tagcagaagc attttttagt gaaatgacgg
    43681 aagagcagct aactgcaaac caagaaaaat ggctcggaga aacgttgcaa gaaatcatgg
    43741 aaatggaatg atcaagaatg aaaccgaaaa aattacaact taaaaatttt ggtcctttta
    43801 tcaatgagac cgtagatttt tcacgtttga cagaagcacc gctttttttg atcagcggga
    43861 agacaggagc tggcaaaacg acgatttttg atgggatcac cttcgcactt tttggtgaaa
    43921 cttccggaag acttcgctct ggaaaagaga tgcgttcttt gtttgctaca ccagacgaag
    43981 aaacaagcgt gactttttct tttgaacatc agcagatgag ctatgaaatc gaacgaaaac
    44041 cagaacaagt tttagcaaaa cgaaaaggaa acggaacaaa aaaacaggca gccaaagtaa
    44101 cgttgaccat ttttgatggg aaaggaaaag aaataaaaca aatcacaaaa cgtacagaag
    44161 cagatcagtt gatcagagaa ctgatgaatc tcgatgcgaa acagttttct caaatcgttt
    44221 tactacccca aggagaattc cgtaattttt tggtttcatc aagcagtgat aaagagactg
    44281 ttttacgtca tttattcggt actcaatttt tccaacagtt caatgagcga ttaaaagaaa
    44341 aagcaaaaca acagcaacaa aaattggatc atttagagca agagctgcat cttctgcaaa
    44401 aaaggtttgt tttagtcaaa gaagaggaac cagcagcagg gtttgaagcc gttttagccc
    44461 aatggacaaa ccatcaggca atactcgaaa aacaaatcac ggaagaaaaa gaagctctaa
    44521 cggaacttca ggaaaaacaa aagcaactag aaaattccta ctatcgtttt gaaagcttga
    44581 aaaaaagtta tgaagaaaaa acgatattaa taaacaagca aaaggaatta gctgctcaaa
    44641 aagacgaaat agaggaaaag aaacgatgga ttgggtatta tgaatttacg caacgattag
    44701 tcgaaccaat ccagcgccta caagaaataa aagttgaaaa aatagaactg tcacaaaaaa
    44761 gtagtgagca aacaaagaaa ctagcgatga ctacgcagaa ttatgaagag tggcaaaaaa
    44821 atgaagcaaa ccgcgtacgc cgacaaacaa aaatcaaaga agctgctcaa aaactgcaaa
    44881 acaaacagat gatggtgcca attgtcgaat ccttacgtag taaaaaacaa gacgcagaac
    44941 aattaacaat ttcattggat aaagaagaat tgaatgccga gaagctgtat caaaatctcg
    45001 ctatctatca ggaaagaact cgaattcttc aagaaaattt actggatcag gaaaaactgc
    45061 aagaagatcg tcttgctttt ggacagttaa aatatctaga tgaaaagcag caagaaatag
    45121 aaaaacaaaa agcaaaagac actgggtcgc tcgcacagat aagagaagaa ctcaaaaaag
    45181 caactgaaga aataacaaaa aatagtcagc tattgaaaga acagacagaa caagcagaac
    45241 agctgaaaag ccaatgggca aagcagcaaa ttgctcgtct tcagcttttt ttgcgtccag
    45301 gggagccatg tcttgtttgt ggatcaacgg aacaccccat acaacaatta aaacacgaac
    45361 agccaaataa ggaagatatc ttaaaagtag aacaacaact ggcagaagct gagtctgctg
    45421 tagaaagaac tcagcaaatc attgccaaaa gtgaagcaca tgaaaataat cttcaacaac
    45481 aattatcaga tttagaacaa aaaatcatgg caacgaatat acaattggct gaacaagaag
    45541 aacacttgca acaggctttg aaaaaggcat ttcctgagat aacagaacaa aaaacaaaaa
    45601 caactcttgt agtaatcgaa caatctttag atagacgaaa aagcaagatg gccaatgcaa
    45661 gaatagagct ggaagaaata agacaacaag cagaaaagct cgaacaacaa ttagctgtct
    45721 acaaacagca gcagacagaa aaaaataatc agctccagca actgcaagga gaaatcaaaa
    45781 gtttagaaca acaattgcaa gatacggata gtaactgttt agaagaggag atacgacgac
    45841 ttgaaaaaca gttagaagaa gactcgaatc aactagctgt tgagcagaaa gcaggagtgc
    45901 aattgttgca agatcttcat acgcttcgga cacagcttga tcttcaacat gaacaaatag
    45961 aaaaaataga tgaaaaaata gaaaaggaac aagaaagaat agctaaaaag ttagaaagcc
    46021 agtcgtattt ttcaacaatt gaagaaatct gtgcatttgc acaacagcaa gcacaatata
    46081 aagaaaacca acgtacagtt acttcttatc atgaagagca attagtgaca gctgaccggc
    46141 tgcgtcaatt agaaaatatc cagctaactg agacattccc agatacagaa gagatcagcc
    46201 aacagttaga agaaataaga cgtatgatcg aaataaagca agaaaagata tacggtttac
    46261 aagaacaaaa aattagtaat caaaaaatct acgatgaatg tctttcgatt tatcacacaa
    46321 gccagacgaa attagatgag cttacgcaat tacagcagct ttcgcaaaca ttcaacggag
    46381 aaaatcctaa gaagactagt ttggaacggt atgtgcttca ggtttatctt caagaagtgt
    46441 tacaagtagc aaatgatcat ctccaacgtt taacgaaaaa tcgttatcaa tttgagctag
    46501 cggataccat tggcagttat cgagggaaaa ccggattaga aatcaatatc tatgatgatc
    46561 aggcaggtat gtctcgaagt gcgcataccc tgtctggcgg tgagagtttt attgcagcac
    46621 tttctttagc attagctctt gccgatgtga tccagacaca agctggtggt gtagcaatcg
    46681 atgcattgtt tattgatgaa ggatttgggt cattagatga agaagctttg gaaatggcaa
    46741 tggaagcttt agaaacgatc gaaagtgaag gaagaatgat cggcatcatt agtcatgtaa
    46801 gagaattgaa agaacgagta ttacaacaaa taagaattga tacagaaggt agcggacaaa
    46861 gcaaaatacg ctatcaactt ggataaaaag ggagattggt aactatgaaa tggagtattc
    46921 cagaaaaagt cattgcacgt ggacgtcaat acttgcaaga aggccgagtg ttatcggttg
    46981 tccctgacca agaagaaaac gtgtggcatg cagaagtctt gggcagtgaa ttgtatatgg
    47041 ttgatttgga tggtacagca aaagagatag attactgcca atgtccctat tgggaggaac
    47101 ataaatattg taagcataca gttgctgtgg aactttattt acggtcgaaa aatctatctc
    47161 gtatcatgaa aaaagaccag ccaatgctag aaccggtaaa agcaacaagt gagggagaaa
    47221 tcattgcaaa aggtttttct cgtctaaaaa cacaaaacaa tcctcaagcg gtgcaacctt
    47281 tgattattga ataccaagta gaaacgattg agactaatca gtatcaccca gagctttcta
    47341 ttttggcact ttacttgcgt atcggttcat tggcatcacc gaaaaaaaca tatatcgtaa
    47401 aaaacatcta tgatttttta caagcttaca cagaaaaaga aacttacact gttaataaac
    47461 agtaccagtt tcgtctagat aaacgggcgt ttcaaaaaga agatcaaaaa atactcacgc
    47521 atcttgcagg aagtgctcag acgcatcaat tattaggtac gaacggctta caagtcaaag
    47581 gaaaactaga taaaagatat ctgcttctcc cagtagaaca agcccgcttc ctgttagagc
    47641 agatgaatca gactacacgt ttgcatctgc agataaatga acaaaacgat caaggaatac
    47701 aattttccga tcaaaacaaa cctttatcat tcaaagtgga aaaatttgga gaagattatt
    47761 tgctgcaagc attgaatgat tttgattttt tctttatgca ttatcagtgg ggagttatcc
    47821 aagggacatt ttattctctg acgaaatatc aacaaacggt ttatcaaact tggaaacaat
    47881 tgattcgccg attggagaaa ccagaagtag tgttcaagaa aaaagaatta ccgtctttgt
    47941 ttaaagagat tatccctctg ctgtcagaga tcggcgacgt agctattgcc cctgcagtag
    48001 aagaggaagt agcagatatc cccgtcgaat ttattttctt tttccgaaaa gcaaaaggaa
    48061 aaatccaagc tcgagtcgat ttcgtctatg gcgaagtcat ctattcgact gacccgaagc
    48121 atgaggtctc gacagaacag gcttttcagg tgttacgtga cacagtagaa gagaaacgag
    48181 tacttgatct attcagaatg tatcgctacc agaaaaatga aactggttat gaacgtccat
    48241 tgccaagcgg ggaagaacta tatgcctttt tccgcacaga actatctgtc ttccgtcagt
    48301 ttggtgaagt cagacttgga agaaaattgc gagagttgta tttagatgcg cataaacatc
    48361 aaccgaaaat cgaagtaacc gagaccggtt catggctcga tattcgattc gatgtgacag
    48421 ggatagagga gcaagaaatc gatcatgtcc tgcaaagctt gctgagaaat gatgcttttt
    48481 atacattaga aaatggtcag gttctttctt ttgattcaga agaatttcaa caaacaagcc
    48541 aagtgttgca acaattacgg gaatcgatac gtacagaaga aggaacgatc catgtaccta
    48601 aaaatcaagg attgatcatt caaaatcaat tggaaaaaag caatgctact tttagtgaat
    48661 cgttccaaac gatggtacaa gatctcattc atccagaaag ataccaggca cagcttccca
    48721 aaggattgaa tgcaacgatg agagattatc aaaagcaagg ttttcgatgg ttgaagatgt
    48781 taggtcatta tcagtttggc ggtattttag ccgatgaaat gggacttggg aaaacactac
    48841 agacaattgc ctttttactt tcggaaaaag aagaacggaa aagcttctct gctttgatcg
    48901 tagcgcctgc gagcttaatt tacaactggc aggcagaggt gagaaaattc gccccttctt
    48961 taagtatcca agtaatcaat gggaataaaa aagaacgtga agaattactg gctaaagaca
    49021 cagatatccg agtgacttct tatgccagct taagacagga tctagctaat tatcagtcgc
    49081 aaaaaattga ttatttgatt cttgatgagg cacaaatggt caaaaatagc agtacgaaaa
    49141 ctgcacaagc attgagagaa ttagctgtac ctcagcggtt tgcactgagt gggacaccaa
    49201 tcgagaataa tttagaagaa ttgtggtcat tgtttgcaac gattatgcca ggatttttcc
    49261 cgactaaaac aaaattcagg gaacttgccg cagaagaaat tgcgcaaatg attcgaccgt
    49321 ttattttacg gcgagataaa caaactgtgt tgaaagactt gccggaaaaa acagagatga
    49381 atctatattc tgcacttaca gaagaacaaa aaactgttta tttagcttac ttgcgtcaaa
    49441 tgcgtgaaga aatcacatca atggattctg aagcattcaa gaaaaaccgg atcgggatac
    49501 ttgctggtct gacaagactg cgacaaattt gctgcgatcc tcgtctgttt attgaagatt
    49561 accaaggcgg ttccggcaag ctcgaacaag taaaagatct actggtagct gccaaagaga
    49621 acaaacgaag agttttgctg ttttctcaat ttacagggat gctgactatc ttgcaagaag
    49681 agttagccga gctagggatc tcgacatttt atttaagagg cagtacgaaa ccacaagatc
    49741 ggttaagtat ggtagacgca tttaatgctg gcgaaaaaga tgtttttctg atttccttaa
    49801 aggctggggg aactggattg aatctcacgg gagcagatac ggtcatcttg tatgaccttt
    49861 ggtggaatcc tgccattgaa gaacaagctg ctggacgtgc acatcggatc ggacaaaaaa
    49921 atgtggtaga agtgtggcgt atgatctctg aaggaacgat tgaggaacgc atggattcac
    49981 tccagcaaga aaaacgcgaa ctgttccaaa aagtgatcca aggtaatgaa gaacagttga
    50041 cgaaactgac tgaagaagac atccgcatga ttttaagtgt aggagaaatc gaggagtaag
    50101 agactcgaaa aagcgttcag taatgggtaa gaaagccttt ctaaagaagc gattgtttat
    50161 ttgatttaaa aaatagcaag gaggctggga ttccatttta tcccagcttc cttgctatca
    50221 tttttttatt tctattttta aaggttatac aaagattgtc ttcattgtct ctaacagctg
    50281 atcaaaagaa gaaatctcga tatcgcaaat tggagtctgt tcaattttgc gttctcgatg
    50341 gttgaaccaa agcgcttgcc agttagcact ttttgcacct agaacatcat tgtcgtaatt
    50401 atcgccaacg tataaggtct cttctggaag catatgaaat tctttctcag ctagctgaaa
    50461 aatctctttt tctggttttt ggaaacctgt tgcttgagaa atgagcatat tgcgggaagg
    50521 aatccaattg ttcaattgaa gttgcttcag tttttttgtc tgatggtcag tcggcccatt
    50581 tgtgataatt cctaatggga cattcttttc cttcaagaaa tcgagggttt ttttgacctc
    50641 ctcatgcaag cagatattat caagttcttc ctcgtaaatt ttttgaaata agaggccatc
    50701 ttcttccgta atatgagggt agtctaaatc ttttagtgat tggctgatcc gatgtgctcg
    50761 catatattct agtgtccaat ctcctgccat tacttttggg aagttttcat cactatgatg
    50821 gcggaaccgg atatatagtg gatgcatatc tgcatctgaa acaagcggaa cgactctttt
    50881 gaccgcgttt cgaaatggct gctgctgatc atacatcgta tcatcaacat caaacacaac
    50941 tgatttaatc aaaattttac acgcctttcg gttttcattg attttttcac aaatccttga
    51001 ctattgtaac agaaaaaatt gtctaaaaaa gctgataaat aaaggttttt cttactatat
    51061 ttctatttcc ttgacagaat aaggttttta tatttcagtt tttttcacta aaaatcgtga
    51121 aacacgtcaa taagtttgat gaacaaatta atcattatgg tagaagtcga ttgatttatt
    51181 ttaatgcaat ctctgtggaa ttttcgaaag atttattttt ttaatacagt ctcaatataa
    51241 ctattcaaac ataaaataac gttatttgat ttatttgttt atagtaaatt ttatttagta
    51301 atcattgctt taaaatacta cgcttatata acagagaaaa taagcgttat aataaagaac
    51361 agtattattt aaaatgacag aaaacattac tattaaagaa ataaaaaaca taaaaaatct
    51421 taagaaatcg gtttcattta gcttttgaga taaaataata gtacagtttt atacgctgtt
    51481 tcatatgttt agaaaatttg aattagattt gaaaactcta atttttaaat gataaaaaaa
    51541 gcgagaatgc tggttttact gtatattaac cttagataac tttcattttt ttaaaaaaat
    51601 tatgaaaaaa aggtagctat ttaaaagttg attatgtata atagaaacag atgggagatt
    51661 attatgatct tctgttacaa aaaagtgatt cttatcacga aaaggagtgg tgcacgttgt
    51721 taacattata tacttcccca agttgtactt cctgcagaaa ggctcgtgcg tggttgcaag
    51781 aacatcagat tccatttgtt gaacgtaata ttttttcaga accattgaac agttctgaat
    51841 taaaagcgat tttacaaatg acagaagacg gaacagaaga aatcatctcg acacgttcca
    51901 aagtattcca aaaactgaac atggatttag atgatctgcc gttacaagaa ttattggaac
    51961 ttgtgcaaaa caatcctgga ttgcttcgcc gtccaatcat gattgatgat aaacgtctgc
    52021 aagttggttt taatgaagat gaaattcgtc ggttcctacc gcgcgatgta cgacaattag
    52081 aattacgtca agcacaattg atggctggat tatagaagga taatacgaaa cttggaaaag
    52141 actattacaa agatagtttt tccaagtttt tttgttttta caaaaagtat tcttgattag
    52201 atgtataaaa aggtagtaga agatgatgat tgcacgaaaa atagagaggg aaaattagct
    52261 gaaaagtcgg ctatatagta ttcgtctgcc aaaaatgtta tagttaaata agatagcttg
    52321 aaaggttgaa aaatccgctg gttttattaa attcgcttaa cagcgagatt ttttttcttt
    52381 acatttaagc tgatttcgct acaatgaatc tatattaaac attgtggcaa agtgaggtgt
    52441 agcaaaatgg aaatggaaca tattaatgaa aatacgatcc gtgtactaat tggtcatgaa
    52501 gatttagagg aacggggcgt ttcatttttg gatttacttg gcaatcacaa agaaatcgaa
    52561 aatttctttt atagtatttt ggaagaagtt gatatcgaag aggagttccg aggaagcgaa
    52621 gctgtcactt tccaagtttt gccaaaagga gacggattag aactgtttat cagtaaaaat
    52681 cttccggatg aagaaatttc tcaatcagaa gattctactg ttgattcaga agatgtgagt
    52741 gactttcttc gtcagcagat tattggcagc gatccggagg aagaattatc tggaagcgcc
    52801 ctagaagaac aggaaagaca agcaactttt gcttttgaag attttgaaca agtgatccaa
    52861 cttgcaacag atgtcgaact agagtctgct tggactgatt tgtatttatt cgaagagcgc
    52921 tattacctag tcgttcactt ctggatggaa aatctcaacc aagcggatgt agagaatcag
    52981 attgctcgaa ttttggagtt tgctgaaaag agcgatcgta caccagaaac attgaatgaa
    53041 tatggacaat gtctgatggc gcgtaatgct atcgagcgaa cgaaatttta ttttgtataa
    53101 atcagcatta tagtaagaga ctgtgacaaa aattgtgtcg cagtcttttt ttcgtataaa
    53161 tgtgttcaaa agcttgcatc tgcggtaaca agcccaacca aacgaaaaat attgggaact
    53221 atttttgttt agctgttctt attacttgat gcagaatagc tttttcacgc cctctttttt
    53281 cgtgtaaata aattcttaga cgtaaataag ttcagaggga gaaaaatgct gcttgcaatg
    53341 aatgaatata ataagtgctg ttttgctaaa catgcagaaa aaggaaagaa atattattgt
    53401 cgtggctgtc gaaaaagagt gattttgaaa aagggaaaga aaaaatgtgc tcattttgcc
    53461 catcaaaaat cagataactg ttcggtcttt agtgaaagag aatcaaaaga gcacttacag
    53521 ttaaaggaat gcttcatgga ttggctggga cagtcagtag aaccagtatt tttggaagcc
    53581 tatttgccga ggttgcggca aaggccggat attttgttgg cgaatctagc aatagaaatc
    53641 caatgttcta gactgtctca ccagagattt attgaaagaa cccaaaatta tttgaataac
    53701 agttaccaag tatggtggat acttggtaat tcttttcttg gacaatcgca attctcattg
    53761 atagaaaaaa gttgctgcta ctataataga aaaagaggag tgcattgctg gaaagctgat
    53821 ctcaagaaac aaaagcttta tttgtatcat catattacag agactgtatc agggcatatt
    53881 tccttttgca gtagctgctg gactttttct agtagggacc ttaaagaaat attcactagt
    53941 aacgaaatta aaatgaacca aatgaaaaaa atagaaaaag tgagtgaaga tgggaagaaa
    54001 tggctgacac gacaacttat tcacaagcaa aagaatacag tatccataca agaacaatgc
    54061 tacttgcgtc ataaacatct tttgcatcta tcatcgtgga tctatcaaaa aagtcggttt
    54121 ttcttttatt tacaagaaca ggtttttctt tatcgaatgt tgtacgaaga agccttggaa
    54181 aaccagaaag ttcctgattt caactcatgg ctttgccaaa taaaagaaca taaaagggaa
    54241 tggctttttc ctatgattga tgaagagatg gtctatcagc agttttttaa cgaatgcata
    54301 cacttgtctt ctttgaaaaa atagtaagta taaaaatagg ctaggaatcg gttttctatg
    54361 taaaacaaga tttagttatg ctaaaattga tggaagcaga cacatgaatg agtagaaaag
    54421 ttagatgctg tgacatgtgg atgttagact atgatctatt ttgatagata gagctaaggg
    54481 aagaaaagga gtggatttca tggaagtaaa gcagttgcca aaacgagaag aattgcctga
    54541 aaatttaact tgggacttga ccaagatctt ttcaagcgac caagagtttg atgagaaata
    54601 tttggaatta tcagaagagt taaaacaatc tgaaaaacac aaaggaacac ttgatcaagg
    54661 cgcttctcaa tttttaaatg cgattgaatt cgtattgagg gtttatcgcc aaactgaagt
    54721 catttatgta tatgcgcacc ttaaaaacga tcaagacact ggaaatacag attaccaagc
    54781 gctttatgca agagcaagca gtctgttttc gaaagttagt gaagccgttt cctggtttga
    54841 accagaaata ttgcaattgt cagatgacca gatttggcaa tatttcaaag aagaaccaaa
    54901 attggaagtc tatcgccatt atatccagca aatagtagat aatcgagccc atgtcttatc
    54961 tgctgagcag gaatctcttc ttgctggagc aggtgaaatc tttgatgctt caagtgatac
    55021 atttgctgtt ttgaataatg cagatctagt ttttccaacg attgaaggag aaaatggtga
    55081 aatagtccaa ttatctcatg gcgtgtatgg tcagttgcta gaaagcacgg atcgaagggt
    55141 gcgcgaagca gcatttaagg ggttgtacag tgtttacgaa caatttagaa atacatttgc
    55201 ttctacttta ggcacacata taaaaggaca taattttaaa gcgaaagtcc gtaattacag
    55261 ctctgccaga gaagcgtctt tgagcaataa tcatattcct gaaagtgtat acgatacttt
    55321 ggtagacgtg gtaaacaagc atttgccttt gttacatcga tacatggaat tacggaaacg
    55381 tttattagaa gtggaaaaac tgcacatgta tgatctttat acaccggtct taggggaagc
    55441 tccaattacc tttacgtacg aagaagcaaa agaaaaagct ttagaagcac tgaaaccaat
    55501 gggtgaagaa tacatggcca tcgtagaaaa agcattctct gaacgttgga tcgatgttgt
    55561 cgaaaataaa gggaaacgaa gcggtgctta ttcttcggga agctatgaca caaatccata
    55621 tattttattg aattggcatg atacgctgga tcagctattt acgcttgtcc acgaaatggg
    55681 acatagtgtt catagttatt tcactcgttc gaaccagcct tatgtgtacg gcgactactc
    55741 catcttttta gcagaaattg cttcgacaac gaatgaaaat atcctaacgg agtatttatt
    55801 ggaaacagaa aaagaccctc gtgtacgggc ttatgtactc aaccattact tggatgggtt
    55861 taaaggaaca gttttccgcc agacacaatt cgctgaattc gagcatttca tgcatacgga
    55921 agatgaaaaa ggtgtgccat tgactagtga atacctaagt gatagttatg gtaaattgaa
    55981 tgcaaaatat tatggtccag cagtcgaaga agacccagaa attaaattcg aatggtcacg
    56041 gataccgcat ttttattata attactatgt tttccaatac tcgactggct tttctgctgc
    56101 ttcagcactg gcgaagaaaa tactaaacca ggaaccagag gcactagaga actacttggc
    56161 ttacctaaaa gcaggtaaca gcgattatcc tgtggaagta atgaaaaaag caggagttga
    56221 tatgacacag gctgcatata ttgaagatgc aatgtcgatg tttgaacaac gtctaaatga
    56281 attagaagaa ttgatcgatc gtttataagg ctttctattt ttgattttct cgaatagaaa
    56341 cgaaaaaaat acgtcggctc tcttgtaagg gagtcgacgt atttttt
//
LOCUS       DAFBVQ010000011        52884 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.011, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000011 DAFBVQ010000000
VERSION     DAFBVQ010000011.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 52884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 52884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..52884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.011"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LLC22_000843"
     CDS             complement(26..1522)
                     /gene="lysS"
                     /locus_tag="LLC22_000843"
                     /EC_number="6.1.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysine--tRNA ligase"
                     /protein_id="HBK5434139.1"
                     /translation="MTQEQQHQVEDLNDQMLVRRQKMEQLREDGIDPFGKRFERTHNS
                     EELHELFDPRTKEELAEMGLTASVAGRMMTRRGKGKTGFAHLQDREGQIQIYVRKDQV
                     GDEAYEVFKHADLGDFFGVTGQIMKTDTGEVSIKASEITILSKALRPLPDKYHGLTNI
                     EQRYRQRYLDLISNRESFDRFMKRSQIISEIRRYLDGNGYIEVETPVLHNEAGGAAAR
                     PFITHHNALDIDLYLRIALELHLKRLIVGGMEKVYEIGRVFRNEGIDTTHNPEFTMLE
                     AYTAYTDFNDVMNLTEGIIRNAAEKVLGTAKITYDGQAVDLESDFKRIHMVDAIKEQT
                     GVDFWQEMTLEEALALAEKHNVEVTEAMGVGHVINEFFETFVEETLTQPTFVYGHPVE
                     VSPLAKKNPEDPRFTDRFELFIVGREFANAFTELNDPIDQRERFEAQEKERELGNDEA
                     HGVDEDFLEALEYGMPPTGGLGIGIDRLVMLLTDAQSIRDVLLFPTMR"
     gene            complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LLC22_000844"
     CDS             complement(1633..2637)
                     /gene="dusB"
                     /locus_tag="LLC22_000844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA dihydrouridine synthase DusB"
                     /protein_id="HBK5434140.1"
                     /translation="MEHTWKIGNVEIPNRVVVAPMAGITNSAFRVTVKEFGAGLVVCE
                     MISDQGIHFRNKKTLEMLHIEETEHPLSLQIFGGNKDSLVEAAQFVEENTAADIIDIN
                     MGCPVNKVIKAEAGAKWLLDPEKVYEMVQAVSSAVNIPVTIKMRIGWDEEHVFAVENA
                     LAAQSAGASAIAMHGRTRVQMYEGKADWEVLKEVKKHLTIPFMGNGDVKTPEDAKWML
                     DYVGADGVMIGRAALGNPWMIHRTQHYLETGELIPEPTPAEKIATAKLHLQRLADLKG
                     EKVACREFRTHAAYYLKGIPRAAKVKVAINQTEKQQEINDLLDQFVEKAEKVLLKQTL
                     "
     gene            complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LLC22_000845"
     CDS             complement(2638..3525)
                     /gene="hslO"
                     /locus_tag="LLC22_000845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp33 family molecular chaperone HslO"
                     /protein_id="HBK5434141.1"
                     /translation="MKDYLVKALAHDGFVRAYAVQATNTVAEAQRRHDTWHTSSAALG
                     RTLVGSLLLGATLKGEDKLTVRIQGDGPATGIVVDANGKGDVKGYIKNPHLSLPLNSE
                     GKIDVRGAVGTQGMFTVTKDLGLKEPFSGQTPIVSGEIAEDFTYYLAISEQIPSAVGL
                     SVLVNTDDSIKTAGGFMIQIMPGADEETISKIEEQLKTTPRISTLLDEGQTPEEILKG
                     LLGTEELNILEKMPVQFKCDCSKEKFAEAIIALGAEEIQAMIDEDHGAEAVCSFCNNK
                     YKYSEEELDGLKKEALGGI"
     gene            complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LLC22_000846"
     CDS             complement(3742..5853)
                     /gene="ftsH"
                     /locus_tag="LLC22_000846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent zinc metalloprotease FtsH"
                     /protein_id="HBK5434142.1"
                     /translation="MNKKNNGMMKNALYYVLVILAMVMVVYFIFGNNGQRSSDIEYSK
                     FTEQLQAGKIKEFEVQPANGVYKITGEYKEQQTVANSGGLAILGSTDTTTTHFTTIIL
                     PNDTTLSQVTELAKENKVATTVKEESSSGIWVSLLLSFLPIVIIIFFFYMMMGQQGGG
                     GGGGGRVMNFGKSKAKEADKKANRVRFSDVAGAEEEKQELVEVVEFLKDPRRFVELGA
                     RIPAGVLLEGPPGTGKTLLAKAVAGEAGVPFYSISGSDFVEMFVGVGASRVRDLFETA
                     KKNAPAIIFIDEIDAVGRQRGAGMGGGHDEREQTLNQLLVEMDGFDGNEGVIVIAATN
                     RSDVLDPALLRPGRFDRQILVGRPDVKGREAILRVHARNKPMADDVDLKVVAQQTPGF
                     AGADLENVLNEAALVAARRNKKKIDASDIDEAEDRVIAGPAKKDRVISKKEREMVAYH
                     EAGHTIVGLVLSRARVVHKVTIIPRGRAGGYMIALPKEDQFLMTKEDMFEQIVGLLGG
                     RTAEEIIFNVQSTGASNDFEQATALARSMVTEYGMSDRLGPVQYEGNHQVFVGRDYGQ
                     TKAYSEQVAFEIDQEVRKILMEAHDKAREIIEAHRAQHKLIAEKLLEFETLDAKAIKS
                     LFEHGVMPEGTESNDYPSEKEAKTFEEAKRALEEKDAEKQAEEKRDFEEAKHELNEEN
                     KAEHDSDSQQSEDNHSDDQYK"
     gene            complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LLC22_000847"
     CDS             complement(5943..6488)
                     /gene="hpt"
                     /locus_tag="LLC22_000847"
                     /EC_number="2.4.2.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875186.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypoxanthine phosphoribosyltransferase"
                     /protein_id="HBK5434143.1"
                     /translation="MLEKDIERILISQEEIQVRCKELGKELTEIYQNTNPLVVGVLKG
                     AVPFMADIVRSIDTYLELDFMDVSSYGNATVSSGEVKIVKDLDTNVEGRDLLIVEDII
                     DSGRTLAYLVDLFKYRKAKSVKIVTLLDKPEGRVVNIEADYVGFNVPNEFVVGYGLDY
                     AEAYRNLPYIGVLKPSVYQSN"
     gene            complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LLC22_000848"
     CDS             complement(6488..7933)
                     /gene="tilS"
                     /locus_tag="LLC22_000848"
                     /EC_number="6.3.4.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA lysidine(34) synthetase TilS"
                     /protein_id="HBK5434144.1"
                     /translation="MNVEKGGKKAPLLQQSFIRHGNEQGFWQQGSRILAAVSGGVDSM
                     VLLHLLLQVQRQIGFSLGIVHINHQLREESAEEAAYLRSYCEEKNLPLYVSIWEDPAK
                     SAIETEARNFRYQEFTRVMEEGQYDTLMTAHHGDDQIETVLMKIVRGGQLNTFSGIKE
                     VQPFATGRLIRPLLSFSKEDLYTYAAESQLVYFEDQTNQLLDIQRNRLRHLVVPQLKQ
                     ENTQALRHFQQFSQQIQWADQVIQKYMGQLIEKEVEQWEEQFRFSAEMIEEMTDAERY
                     YFFYSFFDKAFSKTGIILKEQQMESILDQWQQKKSQWQLSIGNNWILKREYHFVVLSK
                     KEKQATSQTEDQRLLLIPEQGIYLNETEWIGLVKPENAGDIKATDSWSLFSHDIWIPA
                     DVQLYVEKRKAGDRIKLTENLTKKVSRYFIDQKVPNSQRQHAWIITDAKRNIYSLIPF
                     AFSYLSIREETDKIHYILLYKYQKEAIGRRT"
     gene            complement(8053..8523)
                     /locus_tag="LLC22_000849"
     CDS             complement(8053..8523)
                     /locus_tag="LLC22_000849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein S1"
                     /protein_id="HBK5434145.1"
                     /translation="MSIEVGAKLQGKVSGITNFGAFIDLGAGKTGLVHISEVSNGYVK
                     DIHDVLSVGDEVTVKVISVNDDGKIGLSIRKAQEQPAESGEESRPKKYQQKDPRDNRN
                     RPAQKKSFSRSQPSAQKEDFDSLMSSFLKDSDDRLSSLKRNTEGKRGGRGGRRS"
     gene            complement(8569..8994)
                     /locus_tag="LLC22_000850"
     CDS             complement(8569..8994)
                     /locus_tag="LLC22_000850"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation initiator family protein"
                     /protein_id="HBK5434146.1"
                     /translation="MTKKSNKIAALDTEYAKKKYAEFQQQQRQLIFRRRRLAAIFVGA
                     LVIFAIIGVQIFHDMQRMHQLNELRVEANTEMKEVNADVDQLHQDVSLLKDDEYVAKL
                     ARSKFFYSKDGEKVYPILESNTDSSTNETDQSTSSTTAK"
     gene            complement(9061..9330)
                     /locus_tag="LLC22_000851"
     CDS             complement(9061..9330)
                     /locus_tag="LLC22_000851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding S4 domain-containing protein"
                     /protein_id="HBK5434147.1"
                     /translation="MRLDKFLKISRIIKRRSVAKEVADKGRIQINGKLAKSSSDVKVG
                     DILKVQFGNKTLEVKITELHESTKKEDAQKMYEIISENRTETLEK"
     gene            complement(9341..10936)
                     /locus_tag="LLC22_000852"
     CDS             complement(9341..10936)
                     /locus_tag="LLC22_000852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298177.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5434148.1"
                     /translation="MDHKEMRRVMQGAFVLTIASFIAKVLSALYRIPLQNLVGDEGFY
                     VYQQVYPIYGIAMTLALSGLPQFISKYVAERKNPFERKQALQNLYPLVFWTGVFLWLF
                     VFAFSSWIAWMMGDIQLKPLIQVVSFTFLLMPGLSFYRGNFQGRFLMEPTAVSQVVEQ
                     FVRVFVIVCSAFAFRKLGWTVYQTGTAAMSGAVFGGLCAYGILHYYEQKIHGGALSFR
                     RFPLFKQPSKPLIRRFLVEGGLVSIYSGLLIFFQLIDSFFVKNALEVYGLSEYGAKIA
                     KGVYDRGQPLVQLGLVIATALSATFLPALTRHLTNRIYRQFLQTAKIYLRLTTALALA
                     ASLGLALLLPYINYALFKDYAGNAALVLFVFSIAFTAVIQAYQSIAQSKNSFRPSLKG
                     AGWGLLVKGLTTSFLTGLLGTAGASLSTLLGLGVTLWYFVRIETKELNAFWKERHFGR
                     KLMFSLLCMTVVLLLYYGVLNIVFGPVTHRSTAFFVSVIGVGIGASVFIYAVIRLRLF
                     TVREWLMLPFGKKILRLNKKIKK"
     gene            complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LLC22_000853"
     CDS             complement(10951..14472)
                     /gene="mfd"
                     /locus_tag="LLC22_000853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription-repair coupling factor"
                     /protein_id="HBK5434149.1"
                     /translation="MDIIQLVGKDPQVKEWVSNLEEKMPRQLITGLAGSAKTLLFARA
                     FKKTNKNMIILMPNLYYANQLAEDLQHVIPQDQIHLFPVDEVLSAEMAFSSPEARGER
                     VATLNALQEKKAGIYLLPVASLHKRLPNKKTWLQAQLNWHIGDEIDVENLPRQLTLMG
                     YVREEMVAKPGEFSIRGSIIDIYPLTTTYPVRVELFDVEIDSMRYFEAETQRSIEKTE
                     EIWVSPTSEQVYGPEDLEHGIEQMQKMLEKRLAATTEEADREFLQDYFGQLTSSWQAG
                     VPTEEAKFYSDLLYQESVTILDYFPSNSLLVVDDYQRIMETNREIEREAAEWQTQKIS
                     ELRVFSEQTFSADIQKIVQKEKFTTTFFSLFQKGMGNLRFQAIHNFQYRTMQQFFGQM
                     PLLKTEMDRWRKQKQTVVIFIPTKDRIRKAEQMLRDEDILVVETEKNALIRGQVQLVE
                     GALQAGFELPQEKIVAITEKEIFQKTTKKQTRRQTVTNAERLKSYNELKAGDYVVHAN
                     HGIGKYIGMETLEVDGVHQDYMTILYQNDDKLFIPVTQLNLIQKYVASEAKAPRINKL
                     GGSEWTKTKRKVSSKIEDIADDLIKLYAARESEKGYAFGPDDAYQKEFENAFPYSETD
                     DQLRSAAEIKRDMEKEKPMDRLLVGDVGYGKTEVALRAAFKAIKESKQVAFLVPTTIL
                     AQQHYETMLERFEGFPVNIGLLSRFRTRKQQKETIEQLRTGQVDIVVGTHRILSKDIE
                     FSDLGLLIIDEEQRFGVKHKERLKQLRAQVDVLTLTATPIPRTLHMSMLGVRDLSVIE
                     TPPANRYPIQTYVMEKNPGAIREAIHREMGRGGQVFYLYNRVETIEQKVEEIQELVPE
                     ARIGYAHGQMTEAQLENTLFEFIEGQYDVLVTTTIIETGVDIPNANTLFVENADYMGL
                     STLYQLRGRVGRSSRVAYAYFMYEQQKILNEVSEKRLQAIKDFTELGSGFKIAMRDLS
                     IRGAGNLLGAQQHGFIDAVGFDMYSQMLSEAVSRKQGKNSQVEKTTVEIDLGVDAYLP
                     ETYVADQRQKIEIYKRIRELDSQEMLDELEDDLLDRFGEYPEEVAHLLTIGQIKMDGD
                     RALLETIRKQEAHIVFTLSKVGTKRYSVEQLFEALTATKLKASLGVEKEQMVIRLTIP
                     NQMEEAVWLQEIQKFVKALREQKYLSA"
     gene            complement(14489..15049)
                     /locus_tag="LLC22_000854"
     CDS             complement(14489..15049)
                     /locus_tag="LLC22_000854"
                     /EC_number="3.1.1.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA hydrolase"
                     /protein_id="HBK5434150.1"
                     /translation="MKMIVGLGNPGTKYQYTKHNIGFMVVDKIAREHQATFKKNPFEA
                     EVAEFFHNGEKILLVKPQTFMNESGRAVGPLMTYFGIYPEELVVIYDDLDLAVGKIRL
                     RQKGSAGGHNGIKSIISHLNTNVFDRIKVGIGRPEGKKTVVQHVLSPFSKENQPLIEE
                     SMCQSVKAVEYLIEGHSFVDAMNRFN"
     gene            15402..16376
                     /locus_tag="LLC22_000855"
     CDS             15402..16376
                     /locus_tag="LLC22_000855"
                     /EC_number="1.1.1.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875171.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-lactate dehydrogenase"
                     /protein_id="HBK5434151.1"
                     /translation="MTAAAEKKDHQKVILVGDGAVGSSYAFALVTQNIAQEVGIVDIN
                     TAKTEGDAIDLSHALAFTSPKKIYSATYADAHDADLVVITAGAPQKPGETRLDLVNKN
                     LKINRDVVTQIVESGFNGIFLVAANPVDILTYSTWKFSGFPKERVIGSGTSLDSARFR
                     QALAELVDVDARNVHAYILGEHGDSEFPVWSHANVAGLQIYEWVKNNPEIDEEAMVNL
                     FFGVRDAAYTIIEKKGATFYGIAVALARITRAILDDENAVLPLSVFMNGEYGLNDIYI
                     GAPAVINRQGIQKVIEIPLSDSEQDRMAASAKQLKEILDEAFAKLDAE"
     gene            16546..17946
                     /locus_tag="LLC22_000856"
     CDS             16546..17946
                     /locus_tag="LLC22_000856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L,D-transpeptidase/peptidoglycan binding
                     protein"
                     /protein_id="HBK5434152.1"
                     /translation="MTRSSHRKKSKHVALLSVLGVLLVLISFYTYRSTYYTKHFLPNT
                     EINGINVSNLTVEKANEKLKEAYSDKKLAIKEDGKVWQEVPKSELGYKDDFTSELSPI
                     LNEQNGWTWGMTYVSAAEKQEIDPVSQNHQKLDTTVQTLTTKLTDLNKDRTPTTDATI
                     EKAGDSFVIKPEVNGNTIDVDAAVKQLKSAVNSGKDTIELTEFKEKPKVTSEDSSLKE
                     QLASMNAIANVKATYSINGETFQIPSSDIMSWLTYNDGKVDLDTEQVRQYVTDLGTKY
                     NTSTNDTKFKSTKRGEVTVPVGTYSWTIQTDSETEALKKAILAGQDFTRSPIVQGGTT
                     ADHPLIEDTYIEVDLENQHMWYYKDGKVALETDIVSGKPTTPTPAGVFYVWNKEEDAT
                     LKGTNDDGTPYESPVNYWMPIDWTGVGIHDSDWQPEYGGDLWKTRGSHGCINTPPSVM
                     KELFGMVEKGTPVLVF"
     gene            complement(18024..18746)
                     /locus_tag="LLC22_000857"
     CDS             complement(18024..18746)
                     /locus_tag="LLC22_000857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434153.1"
                     /translation="MSGHSKWHNIQGRKNAQDAKRGKVFQKLSREIYMAAKAGGPDPS
                     MNPALRLVVDKAKAANMPNDNVERAIKKATSAVDETNYDEITYEGYGPGGVGILVHAL
                     TDNRNRTATNVRVAFTRNGGSLGETGSVSYLFDRKGYIAIERDGLTVDEETMFEDVLE
                     AGAEDLQTSPEVFEIYTAPEDFAAVRDELEKEFTLAQAELTMIPQTTIDLNEEQKEQL
                     ERLVDKLEDDDDVSEVFTAAEM"
     gene            complement(18825..19331)
                     /locus_tag="LLC22_000858"
     CDS             complement(18825..19331)
                     /locus_tag="LLC22_000858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
                     /protein_id="HBK5434154.1"
                     /translation="MNSSKKQMKNGNIYLVIALIVVIILFYSSSQTYGQQSQVSRLES
                     WLPNQPFKDTLAGIRFNYGGSMVSIDHLGYAKFLEFFLRKGAHFGTYFILGGSLFLGV
                     FPKLKIWWLTAILAWLSATGYAGLDEFHQMMTGGRTPMFQDVMLDSIGALTAVILCVL
                     FAAFKKRL"
     gene            19454..21253
                     /locus_tag="LLC22_000859"
     CDS             19454..21253
                     /locus_tag="LLC22_000859"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M3 family oligoendopeptidase"
                     /protein_id="HBK5434155.1"
                     /translation="MSYSLNWNLDSIFSGGSHSDALNQRMKQLEDQMNEYYHRVTKWS
                     PSSDNAEQLNAILQLQETITNGFTQCSSYITALLSANVNDSDAKVLSGKLYAMLPRLQ
                     SAETVLSKKFAEISDNDWNQMLSQSSFETIAFRLNEIRRDGSQLLSEAEENIINTLSL
                     DGLNAWSSHYDTIVASISIPFEQDGQVVELSAGQAFNKMMGDPDPKVRETLFAAWEEA
                     WKEKAPLFTDTLNHLDGFRLSDYELHGVTDFLQKPLEYNRLKKETLSVMWDTIQKNKQ
                     PLVNYLTRKANLFGKEKMEWQDQDAPIILGDLKEKTFSFDEAAAFIIENFNKFSPKMA
                     KFAQSAFEKSWIEAEDRPGKRPGGYCTELPETKESRIFMTYSNSVNEVATLAHELGHA
                     FHSSTMWDLPSLNREYAMNVAETASTFAELIVADATLKVAKTKEEKINLLDTKLQNAL
                     AMFMNIHSRFIFENRFYEARQEGLVSEDKITEMMVEAQKEGYQGALATYHPYFWAAKL
                     HFFIDDVPFYNFPYTFGYLFSLGIYAYANQKGANFEEEYIHLLRDTASMTTEDLAKKH
                     LNVDLTQPDFWQAGIDMVTEDIQTFMELTEEFI"
     gene            complement(21321..22895)
                     /locus_tag="LLC22_000860"
     CDS             complement(21321..22895)
                     /locus_tag="LLC22_000860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK5434156.1"
                     /translation="MKKSLISAVMVCSMTLTAVASPIAAAADDFDSQIQQQDQKIADL
                     KNQQADAQSQIDALESQVSEINTQAQDLLAKQDTLRQESAQLVKDIADLQERIEKRED
                     TIQKQAREAQVSNTSSNYIDAVLNADSLADAIGRVQAMTTMVKANNDLMEQQKQDKKA
                     VEDKKAENDAKLKELAENQAALESQKGDLLSKQADLNVLKTSLAAEQATAEDKKADLN
                     RQKAEAEAEQARIREQQRLAEQARQQAAQEKAEKEAREQAEAEAQATQASSTAQSSAT
                     EESSATQSSMTEESSSATQSSATEESTTPESSTEESTAPESSATEESTTAPESSATEE
                     STTVPESSATEESTTVPESSTTEESTTPAPTTPSTDQSVDTGNGTGSSTPAPTPTPTP
                     EQPKPVTPAPAPSGSVNGAAIVAEAYKYIGTPYVWGGKDPSGFDCSGFTRYVYMQVTG
                     RDIGGWTVPQESAGTKISVSQAKAGDLLFWGSQGGTYHVAIALGGGQYIHAPQPGESV
                     KVGSVQWFAPDFAVSM"
     gene            complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="LLC22_000861"
     CDS             complement(23150..23659)
                     /gene="mreD"
                     /locus_tag="LLC22_000861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreD"
                     /protein_id="HBK5434157.1"
                     /translation="MLKKETMKYYLPIVLFFLMLIDGHLTRMLGEWSKGTYMSNAHFL
                     ILALLCCSMAFEKRYLLITTIVLGAIYDAYYIGVIGIYAVALPLIVWLMYVMKDVIHV
                     NIFTEFFSMIIFVTGYELFTMVVQLIFKLAVVNNTYFITRFLGPTLLLNMIIFVLFIF
                     PFKKLFSDE"
     gene            complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="LLC22_000862"
     CDS             complement(23663..24517)
                     /gene="mreC"
                     /locus_tag="LLC22_000862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rod shape-determining protein MreC"
                     /protein_id="HBK5434158.1"
                     /translation="MKKFNPNKNIIITLVIVIIVVTILSVTAAQRANEGKPNFFQSIV
                     NDSVAMVDKTISAPVRWVRNGVDSVHNLFSTYAENERLKEKIDSYDDVSQQNKNYERE
                     IEALKKELELNQTLTSYEKVTANVITRSPDSWQDMLIVDKGSKDGIEANMAVMSQKGL
                     IGRVIEVNTASSKIELLSSSNESSNHFPVRVSSANGEAFGLLKNYDEKLHALVVTQLT
                     GDTDIKEGDVVQTSGLGGNSPANLPIGTVIKTKPDSYGLDREVYVKPYAEMYDVSVVT
                     IVQRLAED"
     gene            complement(24672..25310)
                     /locus_tag="LLC22_000863"
     CDS             complement(24672..25310)
                     /locus_tag="LLC22_000863"
                     /EC_number="2.7.6.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thiamine diphosphokinase"
                     /protein_id="HBK5434159.1"
                     /translation="MKILLAAGGNPQNWPQSLLSKYDAYVGIDRGALYLLQAGYPVDL
                     AVGDFDSLSNEEQKEVFAKAKEYTRSPAEKDDTDTQLGILKTFERYPQAEVTLIGATG
                     GRLDHLLANLWLGMEPRFKPFAHQLIIRDCQNYLSYYLPGEHIVRQIPDMKYLAYCCL
                     TPVSNLTLKGSKYVLENKEVEYPTSYASNEFLSDTAEFSFSDGMIAVIQSKD"
     gene            complement(25311..25961)
                     /locus_tag="LLC22_000864"
     CDS             complement(25311..25961)
                     /locus_tag="LLC22_000864"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBK5434160.1"
                     /translation="MKIAPSILSADFANLQRDIELVEKGGADYIHVDVMDGQFVPNIT
                     LGPNIVQAIRPVTKLPLDVHLMIVDPENYIPAFAKAGADIITVHVEATPHIHRALQMT
                     KSLGVKAGVVINPGTPVSMIKHVLPLADQVLVMTVNPGFGGQSFIEETVEKITELADL
                     RRENNWTYAIEVDGGIVPETAKICKDAGADVFVAGSYIYGAENPVGQIERLKEALD"
     gene            complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="LLC22_000865"
     CDS             complement(25974..26873)
                     /gene="rsgA"
                     /locus_tag="LLC22_000865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome small subunit-dependent GTPase A"
                     /protein_id="HBK5434161.1"
                     /translation="MALIKGQIRKAISGFYYVYANGETYQTRGRGNFRNRKITPLVGD
                     QVIFESENQTDGYLLEILPRKNQLVRPPVTNVDLGIIVTSIVEPAFSYNLLDRFLVTL
                     EYESIEPIIFLTKTDLSDDPEKIEEIKQTYTKIGYPVIVPNHTGDTTELIRYFPERLS
                     VFMGQSGAGKSTLLNQISPELNLATGEISDALGRGRHTTRHVELIPIYGGLVADTPGF
                     SSIDFLTIEAGELPRQFPEFVEASVHCKFRECMHAKEPGCEVKHRVETGGIAQTRYDN
                     YLQFLQEIEKRKPMYAKKEGKRK"
     gene            complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="LLC22_000866"
     CDS             complement(27038..29107)
                     /gene="pknB"
                     /locus_tag="LLC22_000866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stk1 family PASTA domain-containing Ser/Thr
                     kinase"
                     /protein_id="HBK5434162.1"
                     /translation="MIELGKKLNGRYQITGNIGSGGMANVFLAHDLILDRDVAVKVLR
                     FDFQNDQTAIRRFQREALAATELVHPNIVSVYDVGEEDNMQYLVMEYVKGMDLKRYIQ
                     THYPVPYETAVNIMQQILSAISLAHNHQIIHRDLKPQNVLIDNEGVVKITDFGIAIAL
                     SETSITQTNTMLGSVHYLSPEQARGSMATKQSDIYALGIILYEMLTGSVPFDGESAVT
                     IALKHFQDDLPSIKALDPNVPQALENVILRATAKEPADRYKSAEEMSDDLSTVLSPAR
                     ANEEKWQPHVMDNETKVITPLTEDAPMPDSFKSMPLPKDKPENETLPEEEEVLPDPKK
                     KGQKKWWLILLAILAVLGIGTAVFFASGGRGEVVVPDVSDLSEASARETLAKAKLEVA
                     TKTEEIADDKIEEGNVVKTDPAAGTTVKQKREVTLYISSGTKKIKLDDYSGKSYEDAE
                     ASLKELGFSADLIQKEEEFSSEVESGMIISQSPSEDTEVDPKTDTITFTVSKGPETVT
                     LSSHVGENYETVRNWLVTQGFNINNISATYDYSDTVPSGSIISQDPASGEVVAEETYI
                     NFVVSQGTEPKLNDISGYTKSEAQSYLASVGAEYIGHETSEYSNTVDKDKVIRTVPGA
                     GTTITKGMVVNVIYSKGPDPASSSSEKDSSDSSSSSSSSSSTSNSSKEESSSSTSSSA
                     STSESSK"
     gene            complement(29104..29844)
                     /locus_tag="LLC22_000867"
     CDS             complement(29104..29844)
                     /locus_tag="LLC22_000867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Stp1/IreP family PP2C-type Ser/Thr phosphatase"
                     /protein_id="HBK5434163.1"
                     /translation="MQIEYQSDVGRRRNTNQDYASVFTSRSGLKLAVLADGMGGHRAG
                     DIASQMAVTNLGEAWEKQEAVDDEKIAQWFIQSIQEENMLIYQRGQEQPEYNGMGTTI
                     VAAALSDDWFTIANVGDSRAYLIREDKIMQLTEDHSLVNELVKSGEISEEMAVNHPRK
                     NILTRSVGMPGTVEVDVSTHLWQLKDRLLLCSDGLTNMLSEEEIGTIINQEGPLSHKV
                     TELIDRANEAGGADNITVLLIEYKEDSV"
     gene            complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="LLC22_000868"
     CDS             complement(29857..31215)
                     /gene="rsmB"
                     /locus_tag="LLC22_000868"
                     /EC_number="2.1.1.176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (cytosine(967)-C(5))-methyltransferase
                     RsmB"
                     /protein_id="HBK5434164.1"
                     /translation="MKKIPKKMKKSVRYMALLTLERVNKGGAYSNLLLNEMIKQSELN
                     QKDVGLFTELIYGTISHQRLLEFYVAPLIAKAKKVDDWVKTLLYLSVYQLEFLDKVPA
                     HAILNEAVEIAKVKGNPGTGKFVNGVLRNYQRQGAPDLQGIADPIERLSVKISLPLWM
                     TKRLVDQIGYEETEKLGLSLYQPSHASARVDTRRLSRDQAITVLQEEEITAEKSQVSP
                     YGIVAKKGHLASSSLFHDGVMTIQDESSMLVAPSMQIEPEHHVLDACAAPGGKTTHIA
                     SFLDPSCGGEVVALDVHEHKVKLIEDNAARLGVSSAVYAQKMDAREVSKQFEAEQFDR
                     ILVDAPCSGLGLLRRKPDIRYKKQPDELANLPKIQLEILESCAPTLKSSGILTYSTCT
                     ILKEENQDVVSAFLERHPDFERIDVLTNPMLQSSIEEKMLTLYPHQFYTDGFFICCLR
                     KK"
     gene            complement(31215..32153)
                     /locus_tag="LLC22_000869"
     CDS             complement(31215..32153)
                     /locus_tag="LLC22_000869"
                     /EC_number="2.1.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287372.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionyl-tRNA formyltransferase"
                     /protein_id="HBK5434165.1"
                     /translation="MTKLVFMGTPAFSVPILEGLIESGYEIQAVVTQPDRPVGRKRVI
                     TPTPVKEAALKHGIRVLQPEKISGSPEMEEIIELVPDVIVTAAFGQFLPEKLLQVPKL
                     GAINVHASLLPKYRGGAPVHYAIMNGEKETGVTIMEMIKKMDAGGIYAQESIPITKQD
                     DVGTMFEKLSLLGRKLLLETLPNILDGQKPVPQDESEATFSPNITREQEAIDWHKTAE
                     EIDNQVRGMRPWPIAFTTYEGIRWKLLSVEVLAETTDKAPGTIIRKDKKNLWIACGKQ
                     TVLAINELQPAGKGKQAVHDFLNGSGQQVQIGQQVK"
     gene            complement(32146..32637)
                     /gene="def"
                     /locus_tag="LLC22_000870"
     CDS             complement(32146..32637)
                     /gene="def"
                     /locus_tag="LLC22_000870"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBK5434166.1"
                     /translation="MRYPILIHPNDKLKRTAQPIDVITDETIALLDNLYETMIANDGI
                     GIAAPQVGQNKRIAVIEVDEGEKFELINPEIIEAKGESLDVEGCLSIPHVYGTVKRAD
                     EVTVRYYDRDGEEIEVTAFGYLARAFQHEIDHLDGILFIEKMIQQIPEEELEEYMEEH
                     LDD"
     gene            complement(32652..35060)
                     /gene="priA"
                     /locus_tag="LLC22_000871"
     CDS             complement(32652..35060)
                     /gene="priA"
                     /locus_tag="LLC22_000871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="primosomal protein N'"
                     /protein_id="HBK5434167.1"
                     /translation="MTLTAEVIVDVPTMQTDQPFTYLVPSEMETALQVGMRVEVPFGN
                     GNRHVQGFVMAIQKSEESANPSLKAVIRLLDLAPVVNEELLSLADYMKKITYAFKITC
                     LQTMLPSVMKAEYDKLIYPLADTPEVQVLFDQREVISWKEAEEEGSLSQLIRWRQEQL
                     VDIKYEVHTRNKVKTIRLVRSLLTEKQIEEEWAKLRQNAKKQKELLLCLSELSQEEPI
                     AYFKNKGISTAVLNQGKEKGWLEFIESERYRDPYKDRVFDQTTALELNAEQKNAVEQI
                     ITAGQQQKDQVFLLEGITGSGKTEVYLQAIADVLSENKTAIMLVPEIALTPQMVERFK
                     GRFGESVAVLHSGLSQGEKYDEWRKIEREEAQVVVGARSAIFAPLKNIGLIIIDEEHE
                     SSYKQDETPRYHARDLAIWRSKYHHCPIVLGSATPSLESRARAQKGVYQLLQLNHRAK
                     AAAQLPAIEIVDMREEFQNHRTSTFSANLQEKIQNRLDKKEQTVLLLNRRGYSSFVMC
                     RDCGFVLPCPNCDISLTLHMDTRSMRCHYCGHEEPIPNRCPNCGGNKIRYYGTGTQKV
                     EEELRELYPQARILRMDVDTTRRKGAHEQILQKFGAKEADILLGTQMIAKGLDFPEVT
                     LVGVLNADTSLNLPDFRSSEHTFQLLTQVSGRAGRAEKAGEVVIQTFNPQHYAIELAK
                     KQNYEQFYQQEMHVRHRGGYPPYYFTVKITASHPEEQVAAKKIFQIANQLKEVLSPQS
                     LLLGPTPSMILRVKNRYYYQLIIKYKHEPNLPHVLDEILNGSQKEQRQGLFVAIDNEP
                     LNFI"
     gene            complement(35313..35618)
                     /locus_tag="LLC22_000872"
     CDS             complement(35313..35618)
                     /locus_tag="LLC22_000872"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287365.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
                     /protein_id="HBK5434168.1"
                     /translation="MMLKPSIDSLLDRVNSKYSLVILASKRAHELDASAQPTLDSFDS
                     VKSVGQALEEIDAGNVVNDPHPELKRERLKMEEEERQAQKEREQHELESRIREEQKM"
     gene            complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="LLC22_000873"
     CDS             complement(35623..36237)
                     /gene="gmk"
                     /locus_tag="LLC22_000873"
                     /EC_number="2.7.4.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010766465.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="guanylate kinase"
                     /protein_id="HBK5434169.1"
                     /translation="MSERGLLIVLSGPSGVGKGTVRKAIFESEDNDFQYSISMTTRKM
                     REGEVEGVDYFFRSKEEFESMIEAGEMLEYAEYVGNYYGTPLSYVNKTLDEGKDVFLE
                     IEVQGAKQVKEKVPDGVFIFLTPPDLAELKSRIVGRGTDADEVIEERMKVAKEEIEMM
                     ALYDYAVVNDEVPLAVERIKNIIASEHFRVDRVIGKYIKMLKEM"
     gene            complement(36724..37008)
                     /locus_tag="LLC22_000874"
     CDS             complement(36724..37008)
                     /locus_tag="LLC22_000874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287356.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434170.1"
                     /translation="MKYYDVTFHELSGKTVVKRDIPSEKNGFDVWKDACADYNENELF
                     ILINDGAYVTMNRKFIVRIDTEEVEDPTEKARSRKDEIMGVVNTLSNMGF"
     gene            complement(37026..37916)
                     /locus_tag="LLC22_000875"
     CDS             complement(37026..37916)
                     /locus_tag="LLC22_000875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YicC family protein"
                     /protein_id="HBK5434171.1"
                     /translation="MKSMTGFGKAIRETKAYQLDIEIKSVNQRFLDVQIRSPKILNFV
                     ENDFRQLIKQQLSRGRIEVFVNLAYIGKNEKQIVINWELIDSLITQLTDGIQQRYGSQ
                     NQVSISRMAERFALDENFVTVEEKPEESMEELAQLALDTLKSALDSIEASREKEGQAL
                     ALVLKKNTEEFKEVLKKLDSFVEIYEKEFQIRYQKKLEEFLGAKVDEQRLLTELAILL
                     ERGDIHEELDRLAIHVQKLDELIEAQCPVGRELDFLIQEMNREINTIGSKSNAIEIKN
                     QVVQSKTILEKIREQVQNIE"
     gene            complement(37936..38154)
                     /locus_tag="LLC22_000876"
     CDS             complement(37936..38154)
                     /locus_tag="LLC22_000876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875139.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdbC family protein"
                     /protein_id="HBK5434172.1"
                     /translation="MAQEFSYEIVEEIAILSENNKGWRKELNLVSWNGRPPKFDLRDW
                     APDHEKMGKGLTLTNEEFEQLQKAIENM"
     gene            complement(38124..39824)
                     /locus_tag="LLC22_000877"
     CDS             complement(38124..39824)
                     /locus_tag="LLC22_000877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="patatin-like phospholipase family protein"
                     /protein_id="HBK5434173.1"
                     /translation="MEIKKVYFSQKMSLYSPIQQAKQPLPFFQSHQESRDAFWRSAKK
                     QCAFKAVSKKYTVYFTIAKSRGDVIFNNLLIEGETFEWKKFFRYMEACARFFIKENCC
                     FLFQSPLSEEWLRIFHKNGYQGTTQLNKKLVYHTALVLGGGGAHGAYQIGVWQALKEH
                     DINFEIITGTSVGALNGALILQGDMKKAVNLWKKLSTRQVLALPEMAAVEDLRERFYR
                     ERRQMTKTALIEGGVSSAPLEKMVKDNLDLSLLKHNPKIRLYTVSTKLPELAEVVTDI
                     QQTKTEEIPDWILASASFYPAMAYRKIGKNKYADGGYRNKIPIDIAINKGATEAFVVD
                     VQGPGPAKKIRMPDIFIHWKCQTLWTLGSFLLFDSQRNQLNLQLGYLEMKKRLGYYYG
                     NWYTFHSVKPARTYWRGFLSYLTKEIQLELSFFKSIKFWQKLRNLYKNRVVPETCGLA
                     MLELLAKKHFLLPNEIYQVDMMIQMICQQDIKSMPDDLLAQIGQLSTEEWRRYRKYQQ
                     KIQNERTKTVYFDYLLQGKRKDRLQHELLKQPVDTLLILYLYYLKEEQPWHKNFHMKS
                     "
     gene            40090..40863
                     /locus_tag="LLC22_000878"
     CDS             40090..40863
                     /locus_tag="LLC22_000878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434174.1"
                     /translation="MTESVYVHIDTTSNAVLTKGLTATDFANSIVHFPQNLLLLDPSA
                     SAGEYESHTGLKVIRGTENIQRFFSSSRNRRGFDELKWIDFTDLTMLKELTPLEISEL
                     LYFGHMKTHLHSPFFYKLQNNFVYFDLNDQLNRIYYRYLDEFYRIFASKLSSILSDKI
                     NVKKSFFKKETPVEKISVELLKEMRNLMQEGIIFSFDQVGLIDGKYRIPIYVIEDYIW
                     KLKGTRYREEEIIATLIYSVTDRHWQLVEDADLSYLPLK"
     gene            complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="LLC22_000879"
     CDS             complement(40944..41513)
                     /gene="thiT"
                     /locus_tag="LLC22_000879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupled thiamine transporter ThiT"
                     /protein_id="HBK5434175.1"
                     /translation="MGKNRVWVEGTIVAALAMVLSLIPIQIGSSFSISLGQIPLTLFA
                     LRRGTKAGMLAGFIWGILHFPLGQVYYLSVVQVLIEYPIAYTFAGAAGLMASNVQKGY
                     VDDNTKQIRKSIVFGALIGALSRYFWHFIAGVVFWGAYALWGMNSWLFSFVMNGASGL
                     STAIVTIIVLLGIQQTTPSIFVPDKRQEL"
     regulatory      complement(41579..41681)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            complement(41687..42658)
                     /locus_tag="LLC22_000880"
     CDS             complement(41687..42658)
                     /locus_tag="LLC22_000880"
                     /EC_number="2.7.6.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016618611.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribose-phosphate diphosphokinase"
                     /protein_id="HBK5434176.1"
                     /translation="MSKHYFDPRLKIFALNSNRPLAEKIAAAVGVELGKSSVTQFSDG
                     EIQVNIEESIRGSHVYVIQSTSSPVNDNLMELLIMIDALKRASAKTINVVMPYYGYAR
                     QDRKARAREPITAKLVANMIQKAGATRMLTLDLHAVQIQGFFDIPVDHLMGAPLIANY
                     FLEKGIKGDDVVVVSPDHGGVTRARKLAEFLKSPIAIIDKRRPKANVAEVMNIIGQVK
                     GKTCVLIDDMIDTAGTITLAANALKEAGATSVYASCTHPVLSGPALQRIEDSAIERLV
                     VTDSIYLPEDRKIDKIDEVSVGGLMGDAIKRIHENKPVSPLFETKNK"
     gene            complement(42752..44125)
                     /gene="glmU"
                     /locus_tag="LLC22_000881"
     CDS             complement(42752..44125)
                     /gene="glmU"
                     /locus_tag="LLC22_000881"
                     /EC_number="2.3.1.157"
                     /EC_number="2.7.7.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346271.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional UDP-N-acetylglucosamine
                     diphosphorylase/glucosamine-1-phosphate
                     N-acetyltransferase GlmU"
                     /protein_id="HBK5434177.1"
                     /translation="MDARYAIILAAGKGTRMKSKLYKVLHPVSGKPMVEHIINRVSET
                     KPDEVITIVGHGAEQVKAQLGERSKYALQAEQLGTGHAVLQAASFLEGKKGTTLVISG
                     DTPLLTTETLNNLFEYHQGKNASATILTAQAENPTGYGRIIRDHIGIVEKIVEQKDAT
                     PEEALVQEINTGTYCFDNEALFDALSKVGTNNAQGEYYLTDIIEILKEEGHTVAAYQT
                     DDFEESMGVNDRIALAKANEIMRKRINQMHMVNGVSFVDSATTYIDAGVEIGPDTLIE
                     AGVQIQGNTVIGSDCVIGSHSKIVDSRIEDHVVIENSVIESSHVKKHADVGPYAHLRP
                     KAEIGENVHIGNFVEVKNAQIGKGTKVGHLTYVGDATLGEEINVGCGVVFVNYDGKNK
                     HHTTVGDHSFIGSSTNIIGPVEVAKNSSIAAGSTITDNIPEYALAIARARQVNKEGYA
                     KKLPYLN"
     gene            complement(44628..45446)
                     /gene="purR"
                     /locus_tag="LLC22_000882"
     CDS             complement(44628..45446)
                     /gene="purR"
                     /locus_tag="LLC22_000882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pur operon repressor"
                     /protein_id="HBK5434178.1"
                     /translation="MKVRRSERLVDMTQYLLNHPHELISLTSFAERYESAKSSISEDL
                     GIIKKTFKERGYGTLETIPGAAGGVLFIPEISYEEAKKYIESLAERLSEQDRLLPGGY
                     VYLSDLLGEPELLRQVGRIIASKYLGEKIDAVMTVATKGVPIAQAVSYYLNAPFVIVR
                     RDSKITEGSTVSVNYVSGSSERIEKMELSKRSLKRGSRVLVVDDFMKGGGTVNGMKSL
                     IEEFESELVGITVFAESKFNGHRAIDDYTSLLYVKDVDTQTKNITVVPGNYFSE"
     gene            complement(45613..46437)
                     /locus_tag="LLC22_000883"
     CDS             complement(45613..46437)
                     /locus_tag="LLC22_000883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBK5434179.1"
                     /translation="MALLSYEFMRRAFLAAIFIAGIAPMLGVFLVIRRQSLMADTLSH
                     VSLAGVALGFFLNLNPTLTTMLVVVLAAVILEYLRTIYRTYSEISIAILMAGGLALAL
                     VLMNLSGGNSATSIQSYLFGSIVTITWEQVIFLGILFVAIGILFFLFKRPMYVLTFDE
                     DTAHVDGLPVHLMSMMFNVITGVAIAVMIPIAGALLISAIMVLPAAIGMRLGKSFNVV
                     IAISVCVGFLGMLSGLTSSFYLDTPPGATITLVFIALFLIVNIIKRILVAFRRKNN"
     gene            complement(46410..47090)
                     /locus_tag="LLC22_000884"
     CDS             complement(46410..47090)
                     /locus_tag="LLC22_000884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBK5434180.1"
                     /translation="MRYIEISDLTFYYDDEPVLEDVSYHVDAGEFVILTGENGAAKST
                     LVKASLGLLKPSKGMIKIAEKNQEGKKLSIGYIPQQVASFNAGFPSTVIELVRSGRYP
                     RGRWFKRLSEKDHQHVQRALEAVGMWDMRNRRIGELSGGQKQRISLARIFATDPDLFV
                     LDEPTTGMDEESRNEFYRLLRHSAHVHGKSVLMITHDHEDIKQYADRQIRLVRKEDSQ
                     WRCFHMNS"
     gene            complement(47113..48051)
                     /locus_tag="LLC22_000885"
     CDS             complement(47113..48051)
                     /locus_tag="LLC22_000885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein"
                     /protein_id="HBK5434181.1"
                     /translation="MKKYLLTATVMIGALLFAACGNTNKEADKKEDLTIVTTFYPMYD
                     FTKEIVGDEGNVKLLIPAGTEPHDFEPSAKERAEISDADVFVYNSSDMEFFVDSLKDS
                     VDSKQTLMIEAAKGIDRLESQEADEHEESEEGHGHSHEYDPHVWLDPVLAIKEVRTIA
                     EELGEKYPDKKETFTKNADAYIKKLEALDQKYSDELKDATNRTFVTQHAAFAYLANQY
                     DLKQVAISGVSPDQEPTPSRLAELKEFVKKNNIKVIYFEENASSKVAETLSNETGVKL
                     EVLNPLESLTNEQIKAGENYISVMEKNLKALKESIN"
     gene            complement(48296..49159)
                     /locus_tag="LLC22_000886"
     CDS             complement(48296..49159)
                     /locus_tag="LLC22_000886"
                     /EC_number="2.7.1.148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-(cytidine
                     5'-diphospho)-2-C-methyl-D-erythritol kinase"
                     /protein_id="HBK5434182.1"
                     /translation="MGERMELIEKAPAKINLGLDVLYRRQDGYHELEMVMSSVDLADH
                     LFFEEITEDKIIVETNKAFLPVDERNNVYQAALLLKNKYNIKTGVKIFVKKNIPVAAG
                     LGGGSTDCAAALRGINQLWNLGCSLEELAEIGLEVGTDVPYCVYGSTAFVGGKGEEIQ
                     VLPSMPQCWVVLVKPRMSVSTRTVFREVDTQAIQHQDIHGLAEAIREQDYQQMIKKMG
                     NSLEDITGKRHPVIHQIKERMIKYGADAALMSGSGPTVFALCQHYSRAQRVYNGLKGF
                     CEEVYLVRTLQ"
     gene            complement(49301..51874)
                     /gene="mprF"
                     /locus_tag="LLC22_000887"
     CDS             complement(49301..51874)
                     /gene="mprF"
                     /locus_tag="LLC22_000887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBK5434183.1"
                     /translation="MKNKRYLMLQWIKEHSLILKLIFFGSVLVFVANQVANIANGMSW
                     QDIWQRMGQQSRMTILLMILAGLLGVTPMLLYDWVTIRVLEKQGKPKMERKEFLLAAW
                     VTNTINNLAGFGGVVGASLRASFYGKQTNRKMVLATVSKVALFMLTGLSVWSFLTFID
                     VFFIQSESIFRSYWIWLFGGSFLAPVIFFFAYLKRKTLFFEFYPKGLLGLLLASFGQW
                     TGALAVFLIIGKLMRIDISMLSIYPMFMIATLIGMLTMVPGGMGTFDVLMILGMSQLS
                     VRQDVAVVWLLYYRLFYYVLPFMTGLLLFITHTGVKINRFLDNIPRLFFQKVAHIVLV
                     SAVYFAGIMMVLLSTITNLSAISRLFQVLLPFSFNFLDQTVNLLVGFLLLGLARALSV
                     KVKKAFLPTIALLSFGILNTITRTLSWQLILVYVLILLAVWLSRKEFYRTKFVYSWGA
                     IIFDASLFGFLFIVYAIAGYHSGRFLVGRITGNHFILFPSDDVWFSGLIGLGISLLAL
                     VALYQYLAEDTTKLGSEYEKDRFDRLLETYGGTATSHQLRLSGYSYFYYQEDDQDQVV
                     FGYQIKGNKCFVLGDPVGNPKMMRAATNQFMKQADCLGYQLAFYKISESYVVMLHELG
                     FHFTKVGEAGIVDLATEDLSRLSQQLEYQRLMKEGYHFTWYDQLPEELHQAVNEVSQK
                     WLQGAREKYFSVGRFDKSYVLSSGVGIVRKDQKVVGFITAQPMTKKQAGYDLLRVLPK
                     ESEELADYLLANLFIVYEKMGYSEANLGLAPLANVGETDFSFFQEKVMHIVYNYGNFF
                     YSFQSAYEKKLKYVDHWEGRYFAYRKGSNFGFATMQLLSLIGKEKGNVPSLAEEVLTE
                     L"
     gene            52015..52821
                     /gene="proC"
                     /locus_tag="LLC22_000888"
     CDS             52015..52821
                     /gene="proC"
                     /locus_tag="LLC22_000888"
                     /EC_number="1.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyrroline-5-carboxylate reductase"
                     /protein_id="HBK5434184.1"
                     /translation="MKVGFIGTGNMAQAIIDGLLKKGTVSKEEVFVSSGHFENAQKFA
                     AETGVHACKSNQEVASQSDIVLLAVKPKIIEKVLEELREYSQKVLFISIASGKSLTDL
                     ETALEDPQASIVRVMPNVNVSVGAGVSAICKNEAATEEQLQQATMIFEAIGSVYPLAE
                     SDFSTFIGLAGSSPAFVYMLIDAMGRTGVLNGLSKQTATEIAAKAIMGSCQKFLSSDK
                     NPWELVDQVSSPGGTTVAGVVALEEAGFIPAIIKGINTTIEKDLEMLNKK"
BASE COUNT        14661 a        11480 c         9505 g        17238 t
ORIGIN      
        1 aattccttag acagctttta ttcgattatc tcattgttgg gaatagcaaa acatcccgaa
       61 ttgattgtgc atcagttagc aacattacta atctgtcgat cccgatgcct agaccaccag
      121 ttggcggcat accgtattct aaggcttcca agaagtcttc gtctacaccg tgagcttcgt
      181 catttcctag ttcacgttct ttttcttgcg cttcgaatct ttctctttga tcaattggat
      241 cgttcagttc tgtaaaggca ttagcaaatt cgcgccccac tatgaatagt tcgaatcgat
      301 ctgtgaatcg aggatcttct ggatttttct tcgctaaagg cgaaacttcg actggatgtc
      361 cgtatacaaa cgtcggttgt gtcaatgttt cttcaacaaa tgtttcaaag aattcattga
      421 taacatgtcc gacacccata gcttcggtta cttctacatt gtgtttttcg gctaaagcta
      481 atgcttcttc caatgtcatt tcttgccaga agtctacacc agtttgttct ttgattgcat
      541 ctaccatatg gatgcgttta aagtcacttt ctaagtcgac agcttgtcca tcatatgtga
      601 tttttgctgt tcctagtact ttttcagctg cgttacggat aataccttct gtcagattca
      661 ttacatcatt gaaatcagta tatgctgtgt atgcttctaa catcgtaaat tctggattat
      721 gtgtagtatc aattccttca ttacggaaaa cgcggccgat ttcataaact ttttccattc
      781 cgccaacaat tagtcgtttt aaatgaagtt ctagcgcaat acgcaaatat aaatcaatgt
      841 ccagtgcatt atgatgcgtg ataaatgggc gtgcggcagc tccacctgcc tcattgtgca
      901 atactggtgt ttctacttca atatagccat tgccatctaa atagcgacgg atttcgctga
      961 taatttggct tcgtttcata aatcggtcaa agctttcgcg attactgatt aaatccaagt
     1021 agcgttgtct gtagcgttgt tcaatattcg ttaagccatg gtatttatct ggcagtggac
     1081 gaagtgcttt tgacaaaatc gtgatttctg aagctttgat agaaacttcg cctgtgtctg
     1141 ttttcatgat ttgtccagtt acaccaaaga aatctccaag gtctgcatgt ttgaatactt
     1201 cataggcctc atcacctact tggtcttttc ttacataaat ttgaatttgg ccttcacgat
     1261 cttgtagatg cgcaaatcca gttttccctt ttcctcggcg agtcatcata cgaccagcta
     1321 cactagcggt caatcccatt tctgctagtt cttcttttgt tcttggatca aatagttcat
     1381 gcaattcttc tgagttgtgc gtgcgttcaa atcgttttcc aaatggatcg attccatctt
     1441 cacgcaattg ttccattttt tgacgacgta caagcatttg atcatttaaa tcttctactt
     1501 gatgttgttg ttcctgtgtc acaaaagttc ctccattctc atgttaatct ctttcctata
     1561 atgccaatga aacacaaaaa aagcaagccg aacttggaat ttcggcttga aaattcacga
     1621 aaaacttaga aatcacaacg tttgtttcaa tagtactttt tccgcttttt ctacaaattg
     1681 atccagcagg tcattgattt cttgctgttt ttctgtctga ttgattgcta ctttcacttt
     1741 cgctgctcga ggaatccctt ttaaataata agccgcatgt gttctgaatt ctctacaagc
     1801 tactttttct cctttgagat ctgctaagcg ttgtaaatga agtttagctg tagcaatttt
     1861 ttcggctggt gttggttcag gaatcagttc tcctgtttcg agataatgct gtgtgcggtg
     1921 aatcatccat ggattgccca gcgctgcacg accaatcatc acaccgtctg caccgacata
     1981 gtcaagcatc cattttgcat cttctggcgt tttgacatcc ccgttcccca taaatgggat
     2041 cgtcaaatgt tttttcactt ctttcaatac ttcccagtcc gcttttcctt catacatctg
     2101 aacccgtgta cgtccatgca tagcgatggc acttgctcca gctgattgtg ctgctaatgc
     2161 attttctaca gcaaagacgt gctcttcatc ccaaccaata cgcatcttga ttgttactgg
     2221 gatatttact gctgaagaaa cagcttggac catttcgtat actttctcag gatctaaaag
     2281 ccattttgct cctgcttctg ctttgattac tttatttact ggacagccca tattgatatc
     2341 tattatatcg gcagctgtgt tttcttcgac aaattgagca gcttcaacta gactatcttt
     2401 atttccgcca aatatctgta aacttaatgg atgttctgtt tcttcaatgt ggagcatctc
     2461 taaagttttt ttgtttctga aatgaatacc ttggtcactg atcatttcac atacgactaa
     2521 gcccgcacca aattctttga cagtgactcg aaatgctgaa tttgttattc cagccatcgg
     2581 tgcaacaacg acacgattag ggatttccac attgccaatt ttccatgtgt gttccactta
     2641 aatccctcct aaggcttctt tcttcaatcc atctaattct tcttcgctat acttgtattt
     2701 gttattacag aaagaacaaa ccgcttctgc accgtgatct tcgtctatca ttgcttggat
     2761 ttcttctgca cctaacgcga taattgcttc tgcaaatttt tcttttgaac agtcacattt
     2821 gaattgaaca ggcatttttt ccaaaatgtt caattcttct gtaccaagca atcctttcaa
     2881 tatttcttct ggtgtctgtc cttcatctaa gagggtagag attcttggtg tcgtttttaa
     2941 ttgttcttcg atcttgctga ttgtttcttc atcggcacct ggcatgattt ggatcatgaa
     3001 tcctcccgcc gtcttgatgc tgtcgtcagt attgaccaat acactcagtc caacagctga
     3061 agggatttgt tctgagatag caagatagta agtaaaatct tcagcgattt ctccagaaac
     3121 aatcggcgtt tgcccagaaa aaggttcttt taatcctaag tcttttgtga cagtaaacat
     3181 tccttgtgtt ccaactgctc cccgcacatc gattttacct tcactattta gaggaagact
     3241 gagatgcgga tttttgatgt aacctttcac atctcccttt ccatttgcat ctactacaat
     3301 tcctgttgct ggaccatcgc cttggattcg aacagttagt ttgtcttctc ctttgagcgt
     3361 cgcaccaagt agcagactac cgaccaatgt ccgtcccaaa gcagctgagg aggtgtgcca
     3421 agtatcatga cgtctttgtg cctccgctac ggtatttgtt gcttgaacgg cgtatgctcg
     3481 gacgaatccg tcgtgagcaa gtgccttaac caaataatct ttcatttgtt atgtactcct
     3541 ttttccgttt ttaaactcat agtgaatcat actagcaact actgcttttt tcaactttgg
     3601 aatgcttctt ttaaaaataa ttcagaatca tctagaaaac aggacatcac cctatttaca
     3661 acttaaataa agaaatctcc cgaaaaccgg tttttgttcc ggttttcggg agtcatatca
     3721 gatcaattga cctatatttt tttatttgta ttgatcgtct gaatgattat cttctgattg
     3781 ttgagaatct gaatcatgtt ctgctttatt ttcctcattc agttcatgtt ttgcttcttc
     3841 aaaatcacgt ttttcttccg cttgtttttc agcgtctttt tcttccaaag cacgttttgc
     3901 ttcttcaaaa gttttcgctt ctttttcgct tggataatca tttgactcag taccttcagg
     3961 catcacaccg tgttcaaaca atgacttgat tgctttggca tccaatgttt cgaattccaa
     4021 aagtttttca gcaatcagtt tatgctgtgc acgatgagct tcgatgattt ctcgagcttt
     4081 atcatgagct tccatcaaga tttttcgtac ttcttgatca atctcgaaag cgacttgttc
     4141 cgagtaagct tttgtttgac catagtcgcg gccaacaaac acttgatggt ttccttcata
     4201 ttgaacagga cctaaacgat cactcattcc atattctgtt accatgcttc gtgctagagc
     4261 tgtcgcttgc tcaaagtcat tggaagcacc agttgattgg acattgaaga tgatttcttc
     4321 agctgtacgt ccaccaagta agcctacgat ttgttcaaac atatcttctt tcgtcatcaa
     4381 gaactgatct tcttttggta aagcgatcat atatccgccg gcgcgtccgc gagggatgat
     4441 cgttactttg tggacgaccc gagcgcgact caatactaat ccgacaatcg tatgaccagc
     4501 ttcgtgataa gcaaccattt cgcgttcttt tttgctgatt acgcgatctt ttttagctgg
     4561 acctgcaatc acgcgatctt ccgcttcatc gatatcagaa gcatcgattt tctttttatt
     4621 tcttctagca gctactaacg ctgcttcatt caagacattt tctaaatctg ctccggcaaa
     4681 acctggtgtc tgttgagcca caactttcaa gtcaacgtca tctgccatcg gtttattccg
     4741 tgcatggact cgcaagattg cttcacgacc ttttacatct ggacgtccaa ctaaaatctg
     4801 gcggtcaaaa cggcctggac gtagtaacgc tgggtctagt acatcagaac ggttggttgc
     4861 agcaatgacg attactcctt catttccgtc gaagccatcc atttctacaa gcaattggtt
     4921 caatgtttgt tcgcgttcat catgtccgcc gcccataccg gcaccacgtt gacgacctac
     4981 cgcatcaatt tcatcaatga aaatgatagc tggtgcgttt ttcttcgctg tttcaaacaa
     5041 atcacgaaca cgacttgctc caacaccgac aaacatttct acgaaatcag aacccgagat
     5101 cgagtaaaac ggtactccag cttctccggc aacagctttt gctaataagg ttttacctgt
     5161 tcctggaggt ccttctaaaa gtacacctgc cgggatacgg gcacctaatt caacaaatcg
     5221 gcgaggatct ttcagaaatt caacaacttc aactagttct tgtttttctt cttccgcacc
     5281 cgctacatca gaaaaacgta cgcgattagc ttttttgtct gcttctttgg cttttgattt
     5341 accaaagttc atgacacggc cgccaccgcc accgccgccg ccttgttgtc ccatcatcat
     5401 gtaaaagaaa aagatgatga ttacgattgg caagaagcta agcaataggg aaacccatat
     5461 accgctgctt gattcttctt ttactgttgt agcaactttg ttttcttttg ccagttctgt
     5521 tacttggctc aatgttgtat catttggcaa aatgattgtt gtgaaatggg tagtagtcgt
     5581 atctgttgaa cctaagatag ctaacccacc gctgttagcg acggtctgct gttctttgta
     5641 ttcaccagtg atcttatata caccatttgc aggctgcact tcaaattctt tgatcttgcc
     5701 tgcttgtagt tgttctgtga attttgagta ctcgatatct gacgatcgct ggccgttatt
     5761 accaaaaatg aaataaacga ccattaccat cgctaagatt acgaggacat aatacaaggc
     5821 atttttcatc atgccgttgt tctttttgtt catagttgcc ctccctaagc gtcaatttaa
     5881 tttaacagtt ttttatcaat cctgaccatt ctattgtacc ataatttaat tgagatacag
     5941 cattaatttg attgataaac actaggtttc aatacaccga tgtacggaag gttacgatat
     6001 gcttctgcat aatccaagcc ataaccgacc acaaattcat ttggtacgtt gaagccaaca
     6061 taatctgctt cgatatttac tactcttcct tcaggtttgt caagtagtgt aacaattttg
     6121 actgattttg ctttgcggta tttgaaaaga tccactaaat aagcaagtgt tcttccgctg
     6181 tcaatgatat cttcaacgat caacagatcg cgaccttcta cattcgtatc taagtctttg
     6241 acgattttta cttcccctga cgagactgtt gcattcccgt agcttgaaac atccatgaaa
     6301 tccaattcca aatacgtatc gatagaacga acgatatctg ccatgaatgg taccgctcct
     6361 tttaagacac ctactactag gggattggtg ttttggtaaa tttctgttaa ctctttgcct
     6421 agttctttgc aacgaacttg tatctcttct tgtgagatca aaattctctc aatatccttt
     6481 tccaacatca ggttctcctt ccaattgctt ctttttgata tttgtaaaga agtatgtagt
     6541 gtattttatc agtttcttca cgaatactca aatatgaaaa ggcaaaaggt atcaagctat
     6601 atatatttct tttggcatct gtaatgatcc aagcatgctg cctttgtgaa ttaggtactt
     6661 tctgatcgat aaaatatcta gatacttttt ttgtgagatt ctctgttaat ttaatgcggt
     6721 ctcctgcttt tcttttttcg acatacagtt gcacatcagc aggaatccaa atgtcatgag
     6781 aaaatagaga ccatgaatct gttgctttga tgtcccctgc attttcaggt ttgaccagac
     6841 caatccattc tgtttcattc aaatatattc cttgttctgg aatcagcaac aagcgctggt
     6901 cttctgtctg gctagttgct tgtttttctt ttttagagag tacaacaaaa tgatactctc
     6961 ttttcagtat ccaattattg ccaatactga gttgccattg gctttttttc tgttgccact
     7021 ggtctaaaat cgactccatt tgttgttctt tcaaaataat tcctgttttt gagaatgctt
     7081 tgtcgaaaaa ggagtaaaaa aaatagtatc gttcagcatc tgtcatttct tcaatcattt
     7141 ctgcagaaaa tcgaaattgt tcctcccact gttcgacttc cttttcgatc aactgtccca
     7201 tatatttttg aatgacttgg tctgcccatt ggatctgttg cgaaaattgc tggaaatgtc
     7261 tcaacgcctg tgtattttct tgtttcaatt gaggaactac caaatgacga agccgatttc
     7321 tctggatatc taacaattgg tttgtctgat cctcaaagta aacaagctgc gattccgctg
     7381 cataagtata taggtcttct ttgctaaaac tcagcaacgg acgaatcagt ctgcccgtag
     7441 caaatggttg tacttctttg attccagaaa aagtatttaa ctgtccccca cgaacgattt
     7501 tcattaacac cgtctcgatt tgatcatctc cgtgatgagc agtcatcaac gtgtcatatt
     7561 gtccttcttc catcacgcga gtgaattctt gataacgaaa gttacgagct tctgtttcta
     7621 tggcggattt ggctggatct tcccaaatac ttacatataa agggagattc ttctcttcac
     7681 aatatgagcg aagataggca gcttcttctg ctgattcttc tcttaattgg tgattgatgt
     7741 ggacgatacc taaagaaaaa ccgatttggc gttgcacttg taaaagtaaa tggagcaaaa
     7801 ccatcgaatc aacaccacct gataccgctg ctaaaattct cgatccttgt tgccagaatc
     7861 cttgttcatt cccgtgccga ataaatgact gctgtaatag cggtgctttt ttcccgcctt
     7921 tttcaacgtt catcctttcc acaccctttc ttcctaaaaa aaagagagcg ggaaaacgtc
     7981 taaaacgaca attaacctgc cctctgttga tactatgacc caaatagtcg cactatcatt
     8041 atttgcggct ttttagctgc gacgtccgcc acggccaccg cgctttcctt ctgtgtttcg
     8101 cttcaatgaa gataagcggt catcgctatc tttcaaaaat gaactcatca atgaatcgaa
     8161 gtcttctttt tgagctgaag gttgactgcg agaaaaagat tttttctgtg ctggacgatt
     8221 tcggttgtca cggggatctt tttgttgata ttttttagga cggctttctt ctccagattc
     8281 agcaggttgt tcctgcgctt tccggataga tagtccgatt tttccatcat catttactga
     8341 aataacttta actgttactt catctcctac acttaaaaca tcatggatgt cttttacata
     8401 gccatttgac acttcgctaa tatgaactag acccgttttt ccagcaccta gatcaataaa
     8461 cgcaccaaaa tttgtgattc ctgatacttt tccttgcagt tttgctccta cctcgattga
     8521 cataaaaaaa atgttcctcc taattatttc ccttttttat attcctgctt attttgcagt
     8581 tgtagaacta gttgattgat ctgtttcatt tgtcgagctg tctgtatttg attctaatat
     8641 aggataaact ttttcaccgt cttttgagta aaagaatttg cttctggcaa gtttagctac
     8701 atactcatca tctttcagca atgaaacatc ttggtgcagc tgatcaacgt ctgcgttgac
     8761 ttctttcatt tcagtatttg cttcgactct caattcgttc aattgatgca tcctttgcat
     8821 gtcatggaaa atctgcacac ctattatcgc gaaaatgacc aaagcaccaa caaaaattgc
     8881 agccagtctg cgtcttcgaa aaatcagttg acgttgttgt tgctgaaatt cagcatactt
     8941 tttctttgca tattccgtat ctagcgcagc gattttattg ctttttttcg tcacttggat
     9001 tcgctccaat ctttttgatt gtctttttca ttataccaat atcgtgaaag cttgtctaat
     9061 ctatttctct agtgtttctg tgcgattttc agaaataatt tcgtacattt tttgtgcatc
     9121 ttcttttttg gttgattcat gtaattccgt aattttcact tccaacgttt tgttgccaaa
     9181 ctggactttc aaaatatcgc ctactttgac atcactggaa gatttcgcca atttaccgtt
     9241 gatttgaatt cttcctttat cagctacttc ttttgctact gatcgtcttt tgatgattcg
     9301 ggaaattttt aaaaatttat ctaatcgcat atcttattcc tcacttttta atttttttat
     9361 ttaatcgcag gattttctta ccaaaaggca acattagcca ttctcgtact gtaaacagac
     9421 gaagacgaat cactgcataa atgaacacag aagccccgat cccaactcct atcacgctga
     9481 caaaaaaagc agtggaacga tgagttacag gaccaaatac tatattcaat acaccataat
     9541 acagcagcag tactactgtc atacaaagaa ggctgaacat caacttccgt ccaaaatgcc
     9601 gttctttcca aaaagcattt agctcttttg tttcaattcg aacaaaatac caaagcgtca
     9661 cacctaatcc taaaagggta gacaggcttg cacctgctgt tcctaataaa ccggtcagaa
     9721 aagaagtagt caatcctttt accaatagtc cccatcctgc gccttttaaa gaagggcgaa
     9781 acgagttctt gctttgagca atactttgat aagcttggat gactgcagtg aaagcaatgg
     9841 aaaaaacaaa taatacaagc gctgcatttc ccgcataatc tttaaacaac gcataattga
     9901 tataagggag cagcaaggct aatcccaaag acgcagctaa tgctaaagcg gtcgtcaatc
     9961 taagatagat tttggctgtc tgtaaaaact gacgatagat ccggttggtc aaatgacgag
    10021 tcaacgcagg caggaatgtc gcacttaatg cagtggcaat cactaaacct aattgtacta
    10081 aaggctgacc tcgatcatag accccttttg ctatcttcgc accgtattct gacagtccgt
    10141 aaacttccaa agcatttttt acaaagaaag agtcgatcag ctggaaaaag ataagcaatc
    10201 cactataaat cgaaaccagt ccgccttcta ccagaaaacg ccggatcaag ggctttgacg
    10261 gctgtttgaa caatggaaac cgtcggaagc ttaacgctcc tccatgaatc ttttgttcat
    10321 agtagtgaag gatcccatat gcgcataaac cgccaaaaac agctccactc attgctgccg
    10381 tccctgtttg gtacaccgtc catccaagct ttctaaaagc aaacgcacta cagacaatca
    10441 caaaaacacg aacgaactgc tcaactactt gagaaacagc agttggttcc atcaagaatc
    10501 ttccttggaa attccctcga taaaaagata gaccaggcat cagcaaaaag gtaaaggaaa
    10561 ctacttggat cagcggtttc aattgtatgt ctcccatcat ccaagcaatc cagctgctaa
    10621 atgcaaagac aaacaaccac aaaaagacac ctgtccaaaa tactaaggga taaagatttt
    10681 gcaaagcttg ctttcgctcg aaaggattct ttctttctgc aacgtacttt gatatgaact
    10741 gcggaagacc ggataaagct aaagtcattg ctatcccata aattggataa acttgctgat
    10801 aaacataaaa accttcgtcg ccgactaagt tttggagggg aattcggtaa agggcactta
    10861 atacttttgc tatgaaagaa gcaatcgtca atacaaatgc tccttgcatg acgcgccgca
    10921 tttctttatg atccaaatca ttgctccttc ctacgctgac agatattttt gctcacgcaa
    10981 cgctttgaca aacttttgga tttcctgaag ccatactgct tcttccattt ggttggggat
    11041 cgtcaagcgt atcaccatct gttctttttc aacgcctaga ctggctttta gttttgtcgc
    11101 tgtcagtgct tcgaataact gttccacact atagcgtttt gttccaactt tacttagagt
    11161 aaagactata tgcgcctcct gtttccttat cgtttctagg agcgctcgat cgccatccat
    11221 tttgatctgc ccaattgtca agagatgtgc tacttcttct ggatattctc caaaacggtc
    11281 gagcagatca tcttctagtt catctagcat ttcttgcgaa tcaagttcac gaattcgttt
    11341 atagatctcg attttctgcc gttgatctgc cacgtatgtt tcaggtagat acgcatcgac
    11401 accgaggtcg atctcaacag tggtcttctc cacttgacta ttctttcctt gtttacgaga
    11461 aacagcttcg cttagcattt gagaatacat atcgaaaccg actgcatcaa taaatccatg
    11521 ctgctgagca cctaagagat tacctgcacc gcgaatggaa agatcccgca tcgcaatctt
    11581 gaatccagat cccagttctg taaaatcttt gattgcctga agacgttttt cactgacttc
    11641 gttaaggatc ttctgctgct catacataaa gtaagcatat gcgacacggc tgcttcttcc
    11701 tacccgccct cgcaattggt ataacgtgga taatcccata taatcagcgt tctcaacgaa
    11761 caacgtattt gcgttcggga tatctactcc tgtttcaatg atggttgtag tgacaagaac
    11821 atcatattga ccttcaataa attcaaaaag cgtattttct aattgcgcct ctgtcatttg
    11881 cccatgagca taaccgatcc gtgcttccgg aacgagttct tggatttctt ctactttttg
    11941 ttcgatcgtt tctacccgat tatataaata gaatacttgt ccacctcgtc ccatttctcg
    12001 atggattgct tcgcgaatag ccccaggatt tttttccata acatacgttt ggatcggata
    12061 acgattcgca ggcggtgttt cgattactga aagatcccgc acgcctaaca tcgacatatg
    12121 caaagttctc ggaatcggtg ttgcagtcag agtcaaaaca tccacttgtg cacgtaactg
    12181 tttcaatcgt tccttatgtt ttacaccaaa acgttgttct tcgtcaatga tcagtagacc
    12241 caaatcgcta aattcaatat cttttgacaa aattcggtgg gttcctacaa caatatcaac
    12301 ttgacctgta cgcagttgtt cgatggtttc tttttgttgc tttcttgttc tgaaacgact
    12361 taatagcccg atatttacgg ggaaaccttc aaatctttcc agcatcgttt catagtgctg
    12421 ctgtgccaag atcgttgttg gaactaaaaa ggctacttgt ttgctttcct ttatcgcttt
    12481 aaaggccgct cgaagcgcta cttctgtttt cccataacca acatcaccta cgagtagtcg
    12541 atccattggt ttttcttttt ccatatcccg tttgatctcc gctgcacttc tcaactggtc
    12601 atcagtttca gagtagggga aggcattttc gaattctttt tggtaggcgt catcaggtcc
    12661 aaaagcatat cctttttctg actctcttgc ggcatataat ttgattagat cgtcagcgat
    12721 atcctcgatt tttgaagaga cttttcgctt ggttttcgtc cattcacttc cgcctagctt
    12781 attgatgcga ggcgctttgg cttcagaggc gacatatttt tggatcagat tcagttgagt
    12841 aacaggaata aacagtttgt cgtcgttttg atacaaaata gtcatatagt cttggtgaac
    12901 gccatctact tctagcgttt ccatcccaat gtatttcccg ataccatgat tggcatggac
    12961 aacgtaatct cctgctttta actcattata gcttttcaat cgctctgcgt ttgttactgt
    13021 ttgacgtctc gtttgttttt tcgtcgtttt ttggaaaatt tctttttctg tgatagctac
    13081 tattttttct tgaggaagtt caaaaccagc ctgcaaagct ccttcaacta attgtacctg
    13141 tcctctgatc aatgcatttt tttctgtttc tactactaat atgtcttcat ctcgaagcat
    13201 ttgttctgct ttgcgtattc tgtcctttgt cggaataaag atcacaacag tctgtttttg
    13261 cttgcgccaa cggtccattt ctgttttcag caatggcatt tgtccgaaga actgttgcat
    13321 cgtccgatat tgaaaattat ggattgcttg gaaacgaaga tttcccatcc ctttttggaa
    13381 gagtgagaaa aaggttgtgg tgaacttttc cttctgcacg attttttgta tatctgctga
    13441 aaatgtctgc tcagaaaaca cccgcaattc gctgattttt tgagtctgcc attctgccgc
    13501 ttccctttcg atttcccgat ttgtttccat gattcgctga taatcatcaa cgactagtaa
    13561 actatttgaa gggaaataat ccaagatcgt cacagattct tggtaaagaa gatctgagta
    13621 gaattttgct tcttctgtcg ggacacctgc ttgccagctt gaagtcagct gaccgaagta
    13681 atcttgcaaa aactcgcggt ctgcttcttc tgtggtcgca gcaagccgtt tttctagcat
    13741 tttttgcatt tgctctattc catgttctag atcctctggt ccgtagactt gttcactcgt
    13801 tggggaaacc cagatttctt ccgttttttc gattgagcgt tgtgtttctg cttcaaaata
    13861 ccgcatagaa tctatctcta catcaaatag ttctacacga acaggatagg ttgtcgttaa
    13921 cgggtaaata tcgataatgc ttcctcgaat actgaattct cccggttttg cgaccatctc
    13981 ttctcgtaca tagcccatca aagtcaattg gcgaggaaga ttttccacgt ctatctcatc
    14041 accaatatgc caattcaatt gcgcctgtag ccaagttttc ttattcggca gtcgtttgtg
    14101 caaagatgcg actggcaaca aatagatacc tgcttttttt tcttgaagtg cgttaagcgt
    14161 tgcaactctc tcgcctcgcg cttctggaga agaaaaggcc atttcagcag aaagcacttc
    14221 atccactgga aataaatgga tctgatcttg cggaatcaca tgttgcagat cttctgctaa
    14281 ctgattcgca taatacaaat ttggcatcag aataatcatg tttttatttg ttttcttaaa
    14341 cgctcgagca aatagaagtg ttttcgctga gcccgctaat cctgtgatta gttgtctagg
    14401 cattttttct tctaaattgc tgacccattc ttttacttgc ggatcttttc cgactaattg
    14461 aataatatcc attccttttc ctccttcctc aattgaatcg attcatcgca tccacgaacg
    14521 aatgcccttc tatgagatat tcgactgctt taacagattg acacatgctt tcttctatca
    14581 aaggctgatt ttctttgctg aaaggactaa gcacatgctg gactactgtt tttttccctt
    14641 ctggcctgcc gattcccacc ttgattcgat caaagacatt cgtattcaaa tgggaaataa
    14701 tacttttgat accgttatgc ccgccggcac ttcccttttg acggagccgg atttttccca
    14761 ctgccagatc caaatcatcg tagattacga ctaattcctc tggataaatc ccaaaataag
    14821 tcattagtgg gccgactgca cgaccagatt cattcatgaa tgtttgtggt ttgactaaaa
    14881 ggatcttttc tccattatga aaaaattcgg caacttctgc ttcgaacgga ttttttttga
    14941 aagtagcttg atgctcgcgt gcaattttat ccacgaccat aaagccgata ttgtgttttg
    15001 tatattggta tttggtacct gggtttccta acccgacgat cattttcatt tttgttttcc
    15061 acctaattct aaaaagcagc acaaaaggct ggactgctaa ttagcggtcc agtccatcga
    15121 gcttttttct tttttatact tgtcaatgca tagtataaca caaaacaagg cgtttcggct
    15181 aaaagagaat cgttaataaa tgataaagaa attaaaaatt tcttcaaagt ttaatgaaat
    15241 aattgatata taaaaatagt gaaataacgc acatgtaagc ttttacatat aatacaacct
    15301 tgttatctgt tatattttat agccaaatag cgtgacatgg ggcttgagaa atgttagcat
    15361 aagcatggga aaaaacaaat caatggaagg attgatacta aatgactgca gctgcagaaa
    15421 aaaaagatca tcaaaaagtt attcttgttg gagacggcgc cgtaggttct agctatgcct
    15481 ttgctctagt tactcaaaat atcgctcaag aagtaggtat tgtggatatc aatactgcta
    15541 aaactgaagg agacgcaatt gacttgtctc acgctttggc atttacttca cctaaaaaaa
    15601 tctattctgc tacttacgca gacgcacatg atgctgactt agttgttatt acagctggcg
    15661 caccacaaaa accaggtgaa actcgtttag acttagtaaa caaaaaccta aaaatcaacc
    15721 gcgatgttgt cacacaaatc gttgaatcag gatttaacgg tatcttttta gttgccgcta
    15781 acccagtaga tattttgact tactcaactt ggaaattctc aggtttccct aaagaacgcg
    15841 taatcggttc aggtacctct cttgactcag ctcgtttccg tcaagcactt gcggaattag
    15901 ttgacgttga tgcacgtaac gtccatgctt acatcttagg tgaacacgga gattcagaat
    15961 tcccagtttg gtcacatgca aatgttgccg gcttgcaaat ctatgaatgg gtaaaaaaca
    16021 acccagaaat cgatgaagaa gctatggtta acctattctt tggcgtacgt gacgctgctt
    16081 acacaattat cgagaaaaaa ggcgctactt tctatggtat cgcagtagca ttagcacgta
    16141 tcactcgtgc catcttagat gatgaaaatg ctgttcttcc tttatcagta ttcatgaatg
    16201 gcgaatatgg attgaacgac atctacattg gtgcacctgc tgttatcaac cgtcaaggta
    16261 tccaaaaagt aatcgaaatt cctttaagtg acagcgagca agaccgtatg gctgcttctg
    16321 ctaagcaatt aaaagaaatt ctagatgaag cttttgctaa actagacgct gaataatctt
    16381 tgaacatgac ggaaaacatc tattcggtgt tttccgtttt tttattttat cacccttatg
    16441 gtttctaaat tttttcataa agtagagata accttcgtct tttcctctaa attatgctat
    16501 catgagaccg ttccacccta aacttttact taaggagttg tcgatatgac aagatcttcg
    16561 catcgaaaaa aatcgaaaca tgttgctttg ctttcagttc ttggtgttct cttagtgctg
    16621 atcagctttt atacctatcg cagtacatac tacacaaagc attttttgcc gaatacagaa
    16681 ataaatggaa taaatgtcag caatctaaca gtcgaaaaag caaatgaaaa attaaaagaa
    16741 gcttattctg ataaaaaact ggctattaaa gaagatggaa aagtctggca ggaagtacca
    16801 aaatccgagc tcggctacaa agatgatttc acttcggagc tttctccgat cctaaatgaa
    16861 caaaacggat ggacttgggg aatgacttat gtctcagcgg cagaaaaaca agaaatagat
    16921 cctgtcagtc aaaaccacca aaaactagac actaccgttc agacattgac aactaagctg
    16981 actgatttga acaaagaccg gacacctact actgatgcaa cgatcgaaaa agcaggtgac
    17041 tctttcgtta tcaagcctga agtcaatgga aatacgatcg acgtcgatgc tgcggtcaaa
    17101 caattaaaaa gtgcggtaaa ctctggtaaa gatacaattg aattgactga attcaaagaa
    17161 aaaccaaaag taacatctga agacagctca ctgaaagaac aactcgcatc catgaatgct
    17221 atcgcaaatg taaaagctac ttacagtata aacggtgaga ctttccagat cccatcaagt
    17281 gatattatga gttggctgac ctacaatgat ggaaaagtcg atttagatac agaacaagta
    17341 cgtcaatatg taacagattt aggcacaaag tataacacaa gtacgaatga cacaaaattt
    17401 aaaagtacaa aaagaggaga agttacggtc ccagttggca cttacagttg gacgatccaa
    17461 acagacagtg agacagaagc attgaaaaaa gcgattctgg caggccaaga ttttactcgt
    17521 tcacccattg tgcaaggtgg cacaaccgct gatcatccat tgatcgaaga tacgtatatc
    17581 gaagttgatc tggagaacca gcatatgtgg tattacaaag acggaaaagt ggcccttgaa
    17641 acagatatcg tttccggaaa gccaactaca cctacacctg ctggagtctt ctatgtttgg
    17701 aataaagaag aagatgcaac tttaaaagga acaaatgacg atggaacacc ttacgagagt
    17761 ccggtaaact actggatgcc gattgactgg acaggtgttg gtatccacga ttcagactgg
    17821 caacctgaat acggtggaga cttatggaaa acccgcggtt cacacggctg catcaacacc
    17881 ccaccaagtg taatgaagga attattcggg atggtcgaaa aaggaacgcc tgtattggtc
    17941 ttctaacaaa aataatatat aaaaagaaag cacccgtacg attggtacag gtgctttctt
    18001 tttattatct aacaatgtgc tacttacatt tcagcagcag taaagacttc tgaaacatca
    18061 tcatcgtctt ctagcttatc tactagacgt tccaattgct ctttttgttc ctcatttaaa
    18121 tcaatcgtcg tttgtggaat catcgtcaat tctgcttgcg ccaaagtgaa ctctttttcc
    18181 aactcatctc gtacagcagc aaaatcttct ggtgcagtat aaatctcgaa tacttcagga
    18241 gaagtttgca gatcttctgc ccccgcctct aatacatcct caaacatcgt ctcttcatca
    18301 acagtcaacc catcgcgttc aatagcgata tatcctttgc ggtcaaacaa gtaactgact
    18361 gaacccgttt ctcccagtga tccaccgttt cgagtaaaag ctactcggac atttgtcgct
    18421 gtccgattac ggttatctgt caatgcatgg actaagattc ctactccacc cggaccatat
    18481 ccttcatacg tgatttcatc gtaattcgtt tcatctacgg cactcgtagc ctttttaatc
    18541 gcccgttcca cattgtcgtt aggcatattt gcagcttttg ctttgtccac aacaagccgc
    18601 aaagctggat tcatagatgg atcaggaccg cctgctttag ctgccatata aatttcacga
    18661 gaaagtttct gaaagacttt ccctcgtttt gcatcttggg cattttttct tccttggata
    18721 ttatgccatt tactatgtcc tgacatgatt tttcctccct tgttcttttg agaatacact
    18781 tctattctag tactatttca caaaaaaaca aagccacagc caatctataa acgcttcttg
    18841 aatgccgcaa aaagcacaca taatatcaca gcagtcagag caccgatcga atccaacatg
    18901 acatcttgga acataggtgt tcgtccaccg gtcatcatct gatggaattc gtccaaacct
    18961 gcgtaccctg ttgctgaaag ccaagcaagg atcgctgtca gccaccaaat ttttagcttg
    19021 gggaaaacac ctaaaaacaa gctgcctccc aaaataaaat aggtaccgaa atgtgcgccc
    19081 ttccttaaaa agaactctaa aaatttggcg tagcccagat ggtcgatact caccatactt
    19141 ccaccataat taaaacgtat acccgctaat gtgtctttaa atggctgatt aggcagccag
    19201 ctttctaatc gcgaaacttg tgattgctgt ccgtaagttt gagaagaact gtaaaataag
    19261 attataacga ctatcagtgc gattactaaa taaatatttc cgtttttcat ttgttttttt
    19321 gaagaattca taagtcacct ctgtatttta tcttagactt tttttgaaga aacaacaatc
    19381 attttcatag agacttcttc cataaaaaag tgctatactt aattttgtat tacaatatga
    19441 agggagtttt ttcatgagtt attcattaaa ttggaatcta gattctattt tttccggagg
    19501 cagtcattct gatgctttga accaacggat gaagcaattg gaagaccaaa tgaacgagta
    19561 ttatcaccgc gtaacaaaat ggtcacctag ttctgacaat gcagagcagt taaacgctat
    19621 tcttcaattg caagaaacga ttacgaatgg ttttacccaa tgcagcagct atattactgc
    19681 attgctttct gccaatgtca atgattcaga tgcaaaggtc ttatcaggca agctttacgc
    19741 aatgctgcct cgtctgcaat cagccgaaac tgtattgtca aagaaatttg cagaaatatc
    19801 tgacaatgat tggaatcaga tgctttctca atcttcgttt gaaacaattg cttttcgttt
    19861 aaacgagatt cgtcgtgatg gctcacaatt attatcagaa gctgaagaaa acattataaa
    19921 tacgctttct ttagatggtc taaatgcttg gagcagtcat tatgatacga ttgtagccag
    19981 catttcgatt cccttcgaac aagatggaca agtagtcgaa ttatctgctg gacaagcctt
    20041 caataagatg atgggcgatc cagatccaaa agtcagagaa acacttttcg cagcatggga
    20101 agaagcctgg aaagaaaagg cacccctctt cacggatact ttgaatcatt tagatggttt
    20161 tagactttct gactatgaac ttcatggtgt cacagatttt ctacaaaaac cattagagta
    20221 caatcggttg aagaaagaaa cattgtctgt catgtgggat acaatccaga aaaacaaaca
    20281 accccttgtt aattacttga ctagaaaagc taatcttttc ggtaaagaaa aaatggaatg
    20341 gcaagatcaa gatgcaccta ttattttagg cgatttgaaa gaaaaaacct ttagttttga
    20401 cgaagcagca gcatttatta tcgaaaactt taacaaattc agtccaaaaa tggctaaatt
    20461 tgcccaatct gcttttgaaa agagctggat cgaagcagaa gatcgtcctg ggaaacgtcc
    20521 tggtggttat tgtactgagt taccagaaac aaaagaatca aggatcttta tgacctacag
    20581 taattctgtt aatgaggttg cgacacttgc tcatgaacta ggacatgctt tccatagcag
    20641 cacgatgtgg gatttacctt ctttaaatcg cgaatatgcc atgaatgtcg cagaaacagc
    20701 aagtacattc gcagaactga tcgtagccga tgctacatta aaagtcgcaa aaacaaaaga
    20761 agaaaaaatc aatttgctag atacaaaact gcaaaatgct ttagctatgt tcatgaatat
    20821 ccattcccga ttcatttttg aaaatcgatt ctatgaagca cggcaagaag gattagtctc
    20881 agaagataag atcacagaga tgatggttga ggcgcaaaaa gaaggctatc aaggagcttt
    20941 agctacttac catccatatt tctgggctgc aaaattgcat ttctttattg atgacgtacc
    21001 gttttataac ttcccataca catttggcta cctctttagt ttgggcatct atgcttacgc
    21061 caaccaaaag ggagcaaatt ttgaagaaga atatatccat ttactacgcg atactgcctc
    21121 aatgacgacg gaagatcttg cgaagaaaca tttgaatgtc gatcttaccc aaccagattt
    21181 ttggcaagca ggtatcgaca tggtgactga agatatccaa acgttcatgg aattgacaga
    21241 agaatttatc tgatttctat tttatcacaa taaaaaaaga gttagtccag aatgggctaa
    21301 ctctttttga ttaatcattc ttacatgctg acagcaaagt caggggcaaa ccattgaact
    21361 gaaccaactt ttacgctttc gcctggttga ggagcatgga tatattgtcc tccgcctaaa
    21421 gcaatcgcta cgtggtaagt tccgccttgt gacccccaga ataacaagtc tccagctttt
    21481 gcttgagaaa ctgaaatttt tgttccagct gattcttgag gaactgtcca accaccgatg
    21541 tcacgaccag ttacttgcat gtaaacatag cgtgtgaacc ctgagcagtc aaagccactt
    21601 ggatctttac cgccccaaac atatggagta ccaatatatt tgtaagcttc tgctacgatt
    21661 gctgcaccat tcacacttcc agaaggagct ggagcaggtg ttacaggttt tggttgttca
    21721 ggtgttggtg ttggcgttgg agccggagta ctacttcctg tgccgtttcc tgtatcaaca
    21781 ctttgatctg ttgatggtgt tgtaggcgca ggtgttgttg attcttctgt tgttgaagat
    21841 tcaggcactg ttgttgattc ttctgttgct gaagattcag gcactgttgt tgattcttct
    21901 gttgctgaag attcaggcgc tgttgttgat tcttctgttg ctgaagattc aggcgctgtt
    21961 gattcttctg ttgaagattc aggtgttgtt gattcttctg ttgctgaaga ttgtgtagct
    22021 gatgatgatt cttcagtcat tgaagattgt gtagctgatg attcttctgt tgctgagctt
    22081 tgtgcagtag atgaagcttg agtagcttgt gcttcagcct ctgcttgttc gcgtgcttct
    22141 ttttcagctt tttcttgtgc agcttgttga cgagcttgtt ctgctagacg ttgttgttca
    22201 cgaatacgag cttgctctgc ttcagcttct gctttttgac ggttcaagtc agctttcttg
    22261 tcttcagcag ttgcttgttc agcagctaat gaagttttca gtacgttcaa atcagcttgt
    22321 ttagataaaa gatcgccttt ttgagattcc aaagcagctt ggttttcagc taattctttt
    22381 agtttagcat cgttttcagc ttttttgtct tctacagctt ttttatcttg tttttgttgt
    22441 tccatcaagt cgttgtttgc ttttaccatc gttgtcattg cttgaacgcg tccaatagca
    22501 tctgctaatg aatcagcatt caatacagca tcgatgtagt ttgagcttgt gttgcttact
    22561 tgtgcttcgc gtgcttgttt ttggattgta tcttcacgtt tttcaatacg ttcttgtaaa
    22621 tctgcaatgt cttttactaa ttgtgcagat tcttgacgca atgtatcctg ttttgctaat
    22681 aggtcttgtg cttgtgtgtt gatttcagaa acttggcttt ctaaggcatc gatttgtgat
    22741 tgtgcatctg cttgttgatt tttcaagtct gcaatctttt gatcttgctg ttgtatctga
    22801 gaatcaaaat cgtccgccgc ggcagcgatc ggtgatgcta cggcagtcaa ggtcattgaa
    22861 cataccatta ctgctgatat taaactcttt ttcactcttc attcctccga ctggcttaat
    22921 ttaataaata tctaaatata tttaagtctt tcttaacgat ataaaaattg taccatagca
    22981 gtgtgtcaac gatataatag ttatgttaca aaaatgtttc aaaacaactt ttaaaaatga
    23041 caaaactgtt cgtttcagaa aatgatcatg aaaaagccgc gttaagtcta gcatttctta
    23101 agataacaac gattcttttt cgctttcgac ctaaaaataa aaaaagaaat tattcatcac
    23161 tgaataattt cttaaaggga aaaatgaata atacaaatat aatcatgttc aacagcagtg
    23221 taggtcctaa aaaccttgta ataaaatacg tgttatttac tactgctaat ttaaaaatca
    23281 actggaccac catcgtaaac aattcataac ccgtgacaaa gatgatcata ctgaaaaatt
    23341 cagtaaagat gttgacatgg ataacgtctt tcattacata catcaaccat acaattaaag
    23401 ggagagctac tgcatagata ccgataacgc caatatagta agcgtcatag atagccccga
    23461 gaacaatcgt ggtaatcagt aaataacgtt tttcaaacgc catactgcaa cataataatg
    23521 ccaatatcag aaagtgggca tttgacatat aggtgccttt cgaccactcc cctagcattc
    23581 ttgttaaatg accatctatc aacatcaaaa agaacaaaac gattggcaga tagtacttca
    23641 ttgtttcttt cttcaacatg gactaatcct ccgctagccg ttggacaatc gtcacaactg
    23701 acacgtcata catttctgca taaggtttca cataaacttc ccgatccagc ccataactat
    23761 ctggtttcgt tttaataacc gtaccgatcg gcaagttagc tggagaattc cctccaagac
    23821 cggatgtctg gacaacatcc ccttctttga tatccgtatc accagttaat tgggtcacca
    23881 ctaaggcatg gagcttttca tcatagtttt taagcaaacc aaacgcttcg ccattagccg
    23941 aagatacccg tactggaaaa tgattggagc tttcattaga ggatgacagt aattcgattt
    24001 tagacgaagc cgtattgacc tcgatcactc ggccaatcaa tcctttttgc gacatgactg
    24061 ccatatttgc ttcgataccg tctttagaac ccttgtctac gatcagcatg tcctgccaac
    24121 tgtcaggcga acgagtaatg acatttgccg ttactttttc gtaactagtc agcgtctgat
    24181 tcaactcaag ttcttttttc aacgcttcga tttctctctc gtaattcttg ttttgctgtg
    24241 aaacgtcatc atagctatcg attttttctt ttagccgctc attttcggca taagttgaaa
    24301 aaagattatg gacagaatct actccatttc gtacccaccg tactggggca gagattgttt
    24361 tatcaaccat tgcaacactg tcattaacga tggattggaa gaaattgggc tttccttcat
    24421 tcgctcgctg cgcagcggtc acacttagta tcgtcaccac gatgataaca ataaccaagg
    24481 taataataat atttttatta ggattgaact tcttcacaaa gacacctcga attaattaga
    24541 ctcttgtgtt caattttatc actaaatgcc gtgaaacaaa aggtaagttg ctcctcttaa
    24601 gctttttttt agcaaataat agattctgtc atttttagcc tgaaagacaa atttttttat
    24661 ttgtttatgg atcaatcttt gctttgaata actgcaatca taccatctga aaaagaaaat
    24721 tctgcggtat ctgaaagaaa ttcgttactt gcataagatg tcggatattc tacttcttta
    24781 ttttccaata catacttgct gccttttaat gtaagattcg agacgggagt caagcagcaa
    24841 taagctaaat acttcatatc tggtatctgt cttactatat gctctccagg caaataataa
    24901 gacaaataat tttgacaatc tctgataata agctgatggg caaagggttt gaagcgaggt
    24961 tccataccta accagagatt ggctaaaaga tgatccaatc ttccgcccgt agctccaatc
    25021 aaagtgactt ccgcttgcgg gtaacgttca aatgttttta agatacctaa ctgtgtatct
    25081 gtatcgtctt tttctgcagg ggaacgggta tactctttgg cttttgcaaa tacttccttc
    25141 tgctcttcgt tcgacaatga atcaaaatca cccactgcca gatctactgg gtagcctgct
    25201 tgaagcaggt acagcgcacc acggtctatc ccgacatagg catcgtattt ggacagcaga
    25261 gactgcggcc agttttgcgg attacctcca gcagctaata aaattttcat ttagtctaat
    25321 gcctctttta atcgttcgat ttgtccgact ggattttcgg ctccatagat atatgatcct
    25381 gcaacgaaga catccgcccc tgcatcttta cagatttttg ctgtttctgg aacgattccg
    25441 ccatctactt cgattgcata agtccaattg ttctctctac gtagatcagc gagttccgta
    25501 attttttcta ctgtttcttc aataaagctt tgtccgccga acccaggatt gacagtcatg
    25561 actagtactt gatcagccaa aggcaaaaca tgtttgatca tggagactgg tgttcctgga
    25621 ttgataacta ctccagcttt aactcctaag ctttttgtca tttgaagtgc ccgatgaata
    25681 tgaggagttg cttcgacgtg gacagtaatg atatctgctc cagcttttgc aaatgctgga
    25741 atgtagtttt ctggatcaac gatcatcaga tggacgtcta acggtaattt agtaacagga
    25801 cggattgcct gaacaatatt tggccctaat gtgatatttg ggacaaattg gccatccatt
    25861 acatctacgt ggatgtaatc tgcgcctcct ttttccacta actcaatgtc tctttgtaaa
    25921 ttggcaaaat ctgcactcaa aatggatggt gctatcttca ttcttgtttc ctcctatttt
    25981 cgtttacctt ctttttttgc atacattggt tttctttttt cgatttcttg taagaattgc
    26041 aaataattgt cgtaacgtgt ctgtgcgata ccacctgttt ctactctatg ttttacttcg
    26101 cagccaggtt ctttagcatg catgcactct ctaaatttgc aatggacaga agcttctaca
    26161 aattcaggaa attgtctcgg cagttctcct gcttcaattg tcaaaaagtc aatcgagcta
    26221 aatcctggtg tatctgctac taacccgcca tagataggaa tcagttccac atgacgtgtt
    26281 gtatgccgtc ctcttccaag tgcatcagaa atctctcctg ttgctaaatt cagttccggt
    26341 gatatttgat tcagtagcgt cgattttcct gctccagact gacccataaa gaccgatagc
    26401 cgttctggga agtaacggat cagttctgtc gtatcacccg tatgattggg tacaatcacc
    26461 ggatagccta ttttagtata ggtttgcttg atctcttcga ttttttctgg gtcgtctgac
    26521 aagtcggtct ttgtcaaaaa aataatcggt tcgatcgact cgtattccaa ggtaactaga
    26581 aagcggtcaa gtagattata agaaaatgca ggctctacga tacttgtgac aatgattcca
    26641 agatcaacat ttgtgactgg tgggcgaact aattgatttt ttctcggcaa gatttccaga
    26701 agatagccgt ctgtttgatt ttcactctca aagatcacct gatctccgac aagcggcgtg
    26761 attttccgat tccggaaatt tcctcttcct cttgtttgat aggtctctcc gtttgcgtat
    26821 acatagtaaa aaccgctgat tgcttttctg atttgtcctt tgataagtgc cacctccgtt
    26881 tttgtttatt ttaccatacg aagaggaaag taggtgttat tccatgcaaa cttctcaaag
    26941 tatatggctt gaaaattgat caaaagagat agaaacacaa aaaagagaat gcaacaaatc
    27001 aatgtcgcat tcccttctga tatattttat tcagcactta ttttgaactt tctgaggtgc
    27061 tagctgatga acttgtggag ctggaagatt cttcttttga agagttgctt gtgctactgg
    27121 agctacttga gctgctagaa ctgtctgaag agtctttttc agaactagaa gacgctggat
    27181 ctggtccttt agagtaaatt acgttcacaa ccattccttt ggtaattgtc gttcctgccc
    27241 ctggtactgt acgaatcact ttatctttat ccaccgtgtt tgaatattcg gaagtctcat
    27301 gcccgatata ttctgcaccg acactagcta aataactttg tgcttcgctt tttgtatagc
    27361 cggagatatc attcaattta ggctctgttc cttggcttac gacaaaattg atgtaagttt
    27421 cttctgctac aacttcaccc gaggctggat cctgactgat gatcgaacct gatggtacag
    27481 tgtcgctata gtcataagta gcactaatat tattgatatt gaatccttgt gtaacaagcc
    27541 aattacgaac agtttcgtag ttttctccta catgactact caaagtcact gtttctggtc
    27601 ctttgctgac tgtgaaagta atcgtgtctg ttttaggatc gacttctgta tcttctgatg
    27661 gagattgcga aatgatcatt ccgctttcta cctctgaact gaattcctct tctttttgaa
    27721 tcaagtcagc agaaaaccct aattctttca aacttgcttc ggcatcttca taacttttac
    27781 cactgtaatc atctaatttg atttttttcg tgccgctact aatatacaga gtgacttcgc
    27841 gtttttgctt gactgtcgtt cccgctgccg ggtctgtctt cactacatta ccttcttcga
    27901 ttttgtcatc tgcaatttct tctgtttttg ttgctacttc taatttcgct tttgcgagtg
    27961 tttctctagc agaagcttca gaaagatcag aaacatcagg aacaacaact tctcctcgcc
    28021 cgccagaagc aaagaataca gctgttccga ttcctaaaac agcaagaata gctaatagga
    28081 tcagccacca ttttttctgt cctttctttt taggatcagg cagaacttct tcctcctctg
    28141 gtaaggtttc gttttctggc ttgtcttttg gcagaggcat agatttgaat gaatcaggca
    28201 ttggtgcatc ttccgtaagg ggtgtgataa cttttgtttc attatccatc acatgaggct
    28261 gccatttttc ttcgtttgca cgagctggtg ataatactgt agaaagatca tcagacattt
    28321 cctcggctga cttataacgg tctgcaggtt ctttagccgt tgcccgtaaa atcacgtttt
    28381 ccagtgcttg tggcacattt ggatcaagtg cttttataga tggaagatca tcttgaaaat
    28441 gttttaaagc aattgttaca gcagattcac catcaaacgg tacgctaccc gtcaacatct
    28501 cataaaggat gatccctaaa gcataaatat ctgactgctt cgttgccata cttcctctgg
    28561 cctgctcagg ggacagataa tgaacagatc ctagcatcgt attcgtctgc gtgatcgatg
    28621 tttcagataa agcgatagca atcccgaaat ccgtgatttt tacaacacct tcattatcga
    28681 tcagtacgtt ttggggtttc aaatctcggt ggatgatttg atggttatga gctaaagaaa
    28741 tagcagaaag gatctgctgc ataatattta ctgctgtttc ataaggaaca ggataatgtg
    28801 tttggatata tcgtttcaag tccattcctt tgacgtattc catcaccaga tactgcatgt
    28861 tgtcttcttc accaacatcg taaacactaa caatgtttgg atgaacgagt tctgttgctg
    28921 ctaaagcttc tctctgaaat cgtcgaatcg cagtctggtc attttgaaag tcaaatcgta
    28981 agactttaac tgctacatca cgatccaaga ttaaatcgtg cgccaaaaat acatttgcca
    29041 taccaccgct accgatattt ccagtgattt gataacggcc atttaatttt ttgcccaact
    29101 cgatcataca ctgtcctcct tatattcgat aagaagaacg gtgatattat ccgctccgcc
    29161 tgcttcattg gcacgatcaa tcagctcagt tactttatga gacaatgggc cttcttgatt
    29221 gatgatcgtt cctatttctt cttcagacag catgttcgtc aagccatctg aacataacag
    29281 cagtcgatct tttagttgcc aaagatgagt agaaacatct acttcgactg ttccaggcat
    29341 gccgacagaa cgtgttaaaa tatttttcct tggatggttc actgccattt cttcgctgat
    29401 ttctcctgat ttgactagtt cattgactaa agaatgatcc tccgtcaatt gcatgatttt
    29461 atcttcacga atcaaataag ctctgctatc cccaacattg gcaatcgtga accagtcatc
    29521 tgacagagcg gccgctacga ttgttgttcc cataccgtta tattccggct gttcttgtcc
    29581 acgctgataa atcagcatat tttcttcttg aatcgattga atgaaccatt gggcgatttt
    29641 ttcatcgtca acagcttctt gtttttccca agcttcgcct agattcgtta ccgccatctg
    29701 actggcaatg tctccggcac gatgaccacc catcccgtct gctaatacag caagcttgag
    29761 acctgaacgg ctggtaaata cactggcata gtcttgattt gtgttacgtc gtcttcctac
    29821 atctgattga tattcaatct gcattttttc acctcattac tttttgcgca aacaacaaat
    29881 gaaaaatcca tctgtgtaaa actgatgcgg atacaaagtc aacattttct cttcgattga
    29941 tgattgtagc ataggattgg tcaaaacatc aatcctctca aaatcagggt gtctttccaa
    30001 gaaagcagaa acaacgtctt ggttttcttc ttttaagatc gtacaagtgc tataagtcag
    30061 aataccggaa gactttaaag ttggtgcgca gctttctaaa atttccaatt ggatttttgg
    30121 taaattcgct aattcatccg gctgtttttt ataacgaata tctggttttc gccgaagcag
    30181 cccaagacct gaacaaggcg cgtctactaa aatccgatca aactgctctg cttcgaactg
    30241 tttactgact tctctagcat ccatcttttg agcgtagaca gcagaagaga cacctagacg
    30301 tgctgcatta tcttcaatga gtttgacttt gtgttcgtgt acatctaaag cgaccacttc
    30361 tccaccgcat gacggatcta aaaaagaagc aatatgcgtc gtcttacctc cgggtgctgc
    30421 acaggcatct aagacatgat gttcaggctc gatttgcata gacggcgcta caagcatcga
    30481 actttcatct tggatcgtca tgacgccatc gtggaacaat gagctagaag ctaaatgccc
    30541 ttttttcgct actataccgt atggactgac ttggcttttt tcagctgtga tctcttcttc
    30601 ttgcaaaaca gtgatggcct gatctctgga aagtcggcgt gtatctactc gggcactagc
    30661 atggctaggc tgatatagcg ataaaccgag cttttcagtt tcttcgtatc cgatttgatc
    30721 caccagtcgt ttagtcatcc atagaggcag gctgattttg acagaaagtc tttcgatagg
    30781 atcagcaatg ccttgcagat ctggtgctcc ttgacgctga taattcctca agacaccatt
    30841 tacaaatttc cctgtcccag gatttccttt tacttttgcg atttcgaccg cctcgtttaa
    30901 aatagcatgt gcagggactt tatctaaaaa ttctaattgg tatacagaaa gataaagaag
    30961 cgtcttgacc cagtcatcca ctttttttgc tttagcgatc aatggtgcaa cgtaaaattc
    31021 caatagtcgc tgatggctaa tcgtaccata gatcaattct gtaaataaac ccacatcttt
    31081 ttgatttagc tcgctttgtt tgatcatctc attcaacaaa agattcgagt aggcgccacc
    31141 cttgttcact cgctctaatg tcagtaatgc catatatcgt actgattttt tcattttttt
    31201 agggattttt ttcattattt cacctgctga ccaatctgaa cttgctgacc gcttccgtta
    31261 aggaaatcat gtacggcctg ttttccttta ccagctggct gtaattcatt gatggctaag
    31321 acggtctgtt taccgcaagc aatccataga ttttttttgt ctttccggat gatcgtacca
    31381 ggtgctttgt ctgtagtttc tgccaatact tcaaccgata ataatttcca gcgtatgccc
    31441 tcataggtcg tgaatgcaat tggccaagga cgcattccgc gtacttggtt gtcaatttct
    31501 tctgcagttt tatgccaatc gattgcttct tgttcccgtg tgatgtttgg cgaaaaagtt
    31561 gcttctgact cgtcttgagg tactggtttt tgtccatcca aaatattggg caatgtttct
    31621 agcaatagct ttcttcctaa aaggctaagc ttttcaaaca tcgtccctac atcatcttgt
    31681 ttagtgattg gtatgctttc ttgcgcatag attccgcctg catccatttt tttgatcatt
    31741 tccatgatcg ttacaccagt ttctttctcc ccattcatga tggcataatg aacaggcgca
    31801 cctccccgat atttaggaag taaagaagca tggacattga ttgcccctaa ttttggtact
    31861 tgcaataact tttcaggcaa gaattggcca aatgccgcag tgacgatcac atcaggcacc
    31921 aattcaatga tttcttccat ttctggcgaa ccggagattt tctctggctg cagcacacgg
    31981 ataccgtgct tcagagccgc ttcttttacc ggtgtcggcg taattactcg tttccgccca
    32041 actggacggt cgggctgtgt taccactgcc tggatctcgt aacctgattc tatcagccct
    32101 tcaagaatcg gcacagaaaa agcaggtgtg cccataaata ctagcttagt catcaagatg
    32161 ttcctccata tattcttcaa gttcttcttc cgggatctgc tgtatcattt tctcaatgaa
    32221 caagataccg tctaagtgat cgatttcatg ctggaaggca cgggctaaat agccaaaagc
    32281 cgtcacttct atctcttctc cgtctcgatc ataataacgc acggtcactt catctgctcg
    32341 cttgaccgtt ccatagacat gcggaatact gagacaacct tctacgtcaa ggctttcacc
    32401 ttttgcttcg atgatttctg ggttaatcag ttcaaatttc tcgccttcat ctacttcgat
    32461 cacagcaatt ctcttgtttt gtcctacttg aggagcagcg atccctattc cgtcattcgc
    32521 aatcattgtc tcatataaat tgtctaataa agcgattgtc tcgtccgtga ttacatcgat
    32581 tggctgagca gttcttttta atttatcatt agggtggatc aatataggat agcgcataat
    32641 ttggcccttt cttaaataaa gtttaatggt tcgttgtcaa ttgccacaaa aagaccttgt
    32701 cgctgttctt tctggcttcc attcaaaatt tcatccaaaa catgaggaag attcggttca
    32761 tgtttatatt tgatgattag ttgataataa tatcggtttt tcactctcaa aatcatgctg
    32821 ggcgttggcc ctaatagcaa gctttgaggg cttaacactt cttttagctg attggcaatc
    32881 tgaaagattt tctttgccgc tacttgttct tcaggatggc tggcggttat tttcacagta
    32941 aagtaataag gaggatagcc tccacgatgc cgtacatgca tttcctgctg ataaaactgc
    33001 tcataatttt gttttttagc caattctatg gcgtaatgtt gaggattgaa tgtttggatc
    33061 acgacttcgc ctgctttttc cgctcgccct gctcgtcctg aaacttgggt aagcaattgg
    33121 aatgtatgct cactagaacg aaaatccggt aaattcaggg aggtatcagc attcaacacc
    33181 ccaactaatg tcacttctgg aaagtccaaa cctttagcaa tcatttgtgt ccctaataat
    33241 atatctgctt cttttgcacc gaatttttgt aaaatctgtt cgtgtgcccc ttttcttcga
    33301 gtggtatcta catccatacg caaaatccta gcttgcggat aaagttctcg gagttcctct
    33361 tctacttttt gagtacctgt tccatagtag cggattttat tgccgccaca attaggacag
    33421 cgattgggaa taggttcttc atgtccgcaa taatggcagc gcattgaacg tgtatccata
    33481 tgcagtgtaa gagagatatc gcaattagga catggaagaa caaatccaca gtccctacac
    33541 atcacaaaag acgaatatcc tcgacgattg agcagtagga cagtttgttc ttttttgtct
    33601 aatcgatttt gtattttttc ctgcaaatta gcagaaaaag tagaggtccg atgattctga
    33661 aactcttcac gcatatctac gatctcaata gctggaagct gtgcagctgc tttggctcgg
    33721 tggtttaact gcaataactg ataaacgcct ttttgagctc gtgctcttga ttctaaagag
    33781 ggcgtcgcgc ttcctagaac tattgggcaa tgatgatatt tactgcgcca aattgctaga
    33841 tctctcgcat gataacgcgg tgtctcatct tgtttgtaac ttgattcatg ttcttcatcg
    33901 ataatgatca gcccgatatt tttcagcggg gcaaaaatag cagatcgtgc gcctactact
    33961 acttgcgctt cttcccgctc aatcttgcgc cattcatcat atttttcacc ttgggaaagt
    34021 ccgctatgta agaccgcaac tgattctccg aagcgtcctt tgaatcgctc gaccatttgc
    34081 ggagtcaatg cgatttcagg cactaacata atagccgttt tattttctga caaaacatca
    34141 gcgattgcct gaagatatac ttctgttttc ccgctgccag tgattccctc cagcaaaaag
    34201 acctgatctt tttgctgctg acctgctgtg atgatttgtt cgacagcatt tttttgttct
    34261 gcattcagtt ccaatgccgt cgtttggtca aatactcggt ctttataagg gtcgcgataa
    34321 cgttctgatt ctataaactc cagccagccc ttttcttttc cttgattcaa gacagcagta
    34381 ctgattcctt tatttttgaa ataagcaatt ggttcttctt ggctcagttc agataaacac
    34441 aaaagaagtt ctttttgttt cttggcattt tgccgtaatt ttgcccattc ttcttcgatt
    34501 tgcttttcag ttaacaaaga acggaccaaa cgaatcgttt ttactttatt tcgtgtatgg
    34561 acttcatatt tgatatctac taattgctct tggcgccagc gaatcaattg agaaaggctg
    34621 ccttcttctt ctgcttcctt ccaggaaatc acttctcgct gatcaaacaa tacctgaact
    34681 tctggtgtgt ctgccaaagg atagatcaat ttatcatatt ctgctttcat cacactcgga
    34741 agcatcgttt gtagacaagt gattttgaat gcgtaagtaa tttttttcat ataatcagct
    34801 aatgaaagta attcttcatt gaccaccgga gcaaggtcta gcaaacgaat aactgccttc
    34861 aaagatggat tagctgattc ttctgatttt tggatagcca taacaaatcc ttggacatga
    34921 cgattgccat taccaaaagg gacttctact cgcatcccga cttgcaaagc tgtttccatt
    34981 tcagagggaa ccaaataagt gaatggctga tcggtctgca tagtaggtac gtccacaatg
    35041 acttcagctg ttaatgtcat ggttcgtttc ctcctttttt tgtcttttct tatcaagcga
    35101 caaaaagttc cttgcctatt ttactagaga tcgatggatt tgtcttatct tctgccaaat
    35161 cctaacaaaa aattaacagc agataagaaa aaaaagaact gtgtcaaaaa gttcagacac
    35221 agccttttct accagacaat aagtggcgaa tgtttgaaaa ggaaacagct gggtttgctt
    35281 ttctttttag atgttcgctc tatttttctt tattacattt tttgctcttc acggatacgt
    35341 gattccaatt cgtgttgttc acgctctttt tgtgcttgac gttcctcttc ttccatcttc
    35401 aaacgttcac gttttaattc aggatgtgga tcattgacta catttcctgc atcgatttct
    35461 tctaaagctt gaccgacgct ttttactgaa tcaaaagaat ctagagtagg ctgtgcactt
    35521 gcatccaatt catgcgcgcg tttacttgct aaaatcacta gagaatattt tgaatttaca
    35581 cgatctaata gtgagtcaat tgaaggtttt aacatcataa gactacatct cctttaacat
    35641 tttaatatat ttaccgatta cgcgatctac tcgaaaatgt tcactggcaa taatgttttt
    35701 gattcgttca actgctagcg gcacttcatc atttacaaca gcatagtcgt aaagagccat
    35761 catttcgatt tcttcttttg caactttcat tcgttcttcg attacttcat ctgcatctgt
    35821 tcctcggcct acgatccgtg attttaattc cgctaaatct ggcggagtca aaaagatgaa
    35881 tacaccatcg ggcacttttt ctttgacttg ttttgctcct tggacttcaa tctccaagaa
    35941 aacatctttt ccttcatcca atgtcttgtt gacatatgac aaaggagttc cataataatt
    36001 cccgacatat tctgcgtatt ccagcatctc tccagcttcg atcattgatt caaactcttc
    36061 tttgcttcgg aagaaataat caacgccttc gacctcccct tcacgcattt tacgggtagt
    36121 cattgagatc gaatactgaa aatcattatc ctcactctca aaaattgctt ttcgtactgt
    36181 gccttttcct acaccggatg gaccagacaa cacgattaat aatccacgct ctgacatgac
    36241 gacgtccttt caactagtct ttttgtactt atcgtttatt ttgcactttt tttctgcaac
    36301 tttcaaggtt atctttaatt atagctagaa attggtaaaa aagctaccct gtaccaagag
    36361 gtcgtaaaaa agctgtcctg catcaagtaa taagaacagc caaacataaa cagcttctca
    36421 tgtttttcgt ttggttgggg ttattatcgc agatgcaagc ttttgaacgc cgtgtataag
    36481 aggtcgtgaa gaagccgatt agtttcgagt atgaagaaaa attttgtgaa aatagtttct
    36541 cacatttttg cataaatttg gcttaatacc gagaaaatgg tttttgaaca tcacttattc
    36601 aaaataaaaa aagattgtga cacgaatttt gtcacaacct ttaaatgtat tcctagagca
    36661 aagaagctaa gcgaagaaat ccaattctga ttatttattg tatttctttg ttcagcatcc
    36721 ttgctaaaag cccatattgg acaaagtatt cactacaccc atgatctcat cttttcgaga
    36781 acgtgctttt tctgtcggat cttctacctc ttctgtgtca attcgaacaa taaatttccg
    36841 attcatcgtc acgtaagcac cgtcgttgat caaaataaac agttcgttct cattatagtc
    36901 tgcacaggca tctttccata cgtcaaagcc gtttttttca gaagggatat cccgtttaac
    36961 cacagttttt ccacttaatt cgtggaacgt tacgtcataa tatttcatta tctctacctc
    37021 tttcgtcatt caatattttg tacttgttct ctgatttttt ctaagatcgt cttagactgg
    37081 acgacttgat ttttaatttc gattgcattt gatttggaac cgatcgtgtt gatttcccga
    37141 ttcatttctt ggatcaggaa atctaattcc cgacctacag gacattgtgc ttcgataagt
    37201 tcatctagtt tttgtacatg gatcgccaga cgatccagtt cctcgtgaat atctccgcgt
    37261 tccaacaaga tggctagctc cgtcaacaac cgttgctcat cgactttcgc tccaagaaat
    37321 tcctccagct ttttttgata ccttatttga aattcctttt catagatttc tacaaaacta
    37381 tcgagttttt ttagtacttc tttgaattct tcagtattct ttttcaacac taaagctaaa
    37441 gcttgacctt ctttttctcg actcgcctca atagaatcaa gtgcgctttt caatgtatct
    37501 agagctaact gtgccaattc ttccatgctc tcttccggtt tttcttctac cgttacgaag
    37561 ttttcgtcca gcgcgaagcg ttccgccatc cgactaattg acacttgatt ttgactaccg
    37621 tatcgttgtt gaattccgtc tgtcaattga gtgataagtg aatcaatcaa ttcccagttg
    37681 atgacgatct gtttttcgtt tttgccaata taagctagat tcacaaatac ttcgattcga
    37741 ccgcggctta actgctgttt aataagctga cgaaaatcgt tttcaacaaa gttcaggatt
    37801 ttaggacttc gtatttgaac atctagaaaa cgctggttga cactttttat ttcaatatct
    37861 aactgatacg cttttgtttc gcggatggct ttgccaaaac cagtcatact tttcattcga
    37921 cagggtcctt cctcattaca tattttctat tgctttttgc agttgttcaa actcttcgtt
    37981 cgtcaatgtc aggcctttcc ccattttttc atggtctggc gcccaatctc gaagatcgaa
    38041 ttttggcggg cgaccattcc agctgactag gttcagttct ttacgccacc ccttgttgtt
    38101 ttctgacaat atagcgattt cttctacgat ttcatatgaa aattcttgtg ccatggttgt
    38161 tcctccttga gataatataa atataggatc agtaatgtgt caactggttg cttaagcaat
    38221 tcatgctgca aacgatcctt gcgttttcct tgtagcagat aatcaaaata aacagttttc
    38281 gtgcgctcat tttgtatttt ttgctggtat tttcgatacc ttcgccattc ttcagtactt
    38341 aattgaccaa tttgtgccaa taaatcatcc ggcatacttt ttatatcttg ttggcagatc
    38401 atttgaatca tcatgtctac ttgatagatt tcattgggca gtaaaaaatg tttttttgct
    38461 aaaagttcta gcatcgccaa tccgcatgtc tctggtacga ccctgttctt atataaatta
    38521 cgcagttttt gccaaaattt tatgcttttg aaaaaagata attctaactg aatttctttt
    38581 gttaagtaag acaaaaatcc tcgccagtat gttcttgcag gtttaacaga atgaaatgta
    38641 taccagttcc catagtaata gcctaatcgt tttttcattt ccagatagcc taattgtaaa
    38701 tttaattggt tcctttggct atcaaaaagc agaaagctgc ctagtgtcca caatgtttga
    38761 catttccaat ggataaaaat gtctggcata cgaatttttt tcgctgggcc tggcccttgc
    38821 acatctacga caaatgcctc tgttgctcct ttgttaatcg caatatcaat aggtattttg
    38881 ttgcgatacc caccgtctgc atatttattt tttccgatct ttcgataagc catagcggga
    38941 taaaatgaag cagaggcgag tatccaatct ggtatttctt ctgtttttgt ctgttggata
    39001 tcagtcacta cttccgctag ttctggcagt ttagtagaca ccgtatataa acgtattttg
    39061 ggattatgtt tgagtaagga caaatccaaa ttgtctttga ccatcttttc caatggagca
    39121 gaagaaaccc cgccttcaat tagtgctgtt ttcgtcattt ggcgtctttc tcgatagaag
    39181 cgttcacgaa ggtcttcaac tgcagccatt tctggtaacg caagcacttg tcttgtcgac
    39241 agctttttcc ataaattcac agcttttttc atatctcctt gtaaaatcaa tgcgccgttc
    39301 aacgcaccta ccgaggtacc tgtgataatc tcaaagttga tatcatgttc cttcagcgcc
    39361 tgccacacac caatctgata agcaccgtgt gctcctcctc cacctaaaac aagtgctgta
    39421 tgatagacca gctttttatt taattgtgtg gttccttgat agccgttttt atgaaaaata
    39481 cgcaaccatt cttctgatag aggagattga aataaaaaac aacagttttc tttaataaaa
    39541 aaacgagcgc aagcttccat ataccgaaaa aattttttcc attcaaaagt ttcaccttca
    39601 atcaacagat tattaaaaat aacatctcct ctacttttag caatagtaaa atagacggta
    39661 tattttttcg atactgcttt aaaagcacat tgcttttttg cagaacgcca aaaagcgtct
    39721 ctactttctt gatgactttg aaaaaatgga aggggttgtt ttgcttgctg gataggcgaa
    39781 tacagcgaca ttttctgtga aaagtaaact ttttttatct ccatcgcgct ctcctttttc
    39841 ttcaagtata ccagtacgtc ataaaaaggt catgagtctc gtattcgact ttgtagattc
    39901 cataagaaaa caattcataa aacatccttt aaataaaaaa tacaaaaatc acaaaaatta
    39961 attgaaaatg agagtgtttt caatgaaaac gtgattttgt aatggaattt taaaataaaa
    40021 gaaacaagct tttttaatgc aaatgttgta aaataaaaga gattaagagg aaataagagg
    40081 aggaacatga tgactgagtc agtttatgta catattgata ccacaagtaa tgctgtttta
    40141 acaaaagggc tgactgctac tgactttgca aacagtatcg tgcattttcc tcaaaacttg
    40201 ctcttgcttg atccatctgc ttctgctgga gaatatgaat cccatacagg gctgaaagta
    40261 atccgtggta cagaaaatat tcagcgtttc ttttcctctt ctcgtaacag gcgtggattc
    40321 gatgaattga agtggatcga ctttactgat ttaacgatgc tgaaagaatt gacaccttta
    40381 gaaatttcag aattattata ttttggtcat atgaaaacac atcttcattc gccgtttttt
    40441 tataaactac agaataattt tgtatacttc gatcttaatg atcagctgaa tcggatttat
    40501 tatcgctatt tagatgaatt ttataggatt tttgctagta aattaagttc gatcttgtca
    40561 gataagatca atgtaaaaaa atcttttttc aaaaaagaaa cacctgttga aaaaatcagt
    40621 gtggaattat tgaaagaaat gcgtaatttg atgcaggaag ggatcatttt ttcttttgat
    40681 caagttggtt tgatcgatgg taaatatcgt atcccaatct atgtgattga agattatatt
    40741 tggaaattaa aaggcacccg gtatcgagaa gaggaaatca tcgctacttt aatctactct
    40801 gtcaccgatc gacactggca attggtagaa gatgccgatc tttcttatct gccattgaag
    40861 tagatctatt tcttatcaaa aaataaaaag gaaacaagaa actaggacat gattctgtct
    40921 caagtttctt gcttcttttt tatttacagc tcctgtcgtt tatctggcac aaaaatcgaa
    40981 ggagtcgttt gttggatccc taataaaacg atgatcgtta caatagctgt actcaacccg
    41041 ctggcaccat tcattacgaa agaaaagagc caagaattca tcccccatag tgcatacgct
    41101 ccccagaaaa ccactcctgc aataaaatgc caaaaatatc tggaaagtgc gccaatcaat
    41161 gcaccaaaca cgatgctttt tctaatttgt ttcgtattat cgtctacata gcctttttgg
    41221 acatttgaag ccatgagccc tgctgcgcct gcaaaagtat aggcaatcgg gtactcaatc
    41281 aacacttgaa cgacacttaa ataataaact tgtcccaacg gaaaatgtag gatgccccaa
    41341 atgaaacctg ccagcatccc tgcctttgtc cctcttctta acgcaaaaag agtcaatgga
    41401 atctgcccta atgaaataga aaaactgctg ccgatctgga tcggaatcaa cgacaacacc
    41461 atcgctaacg ctgcaacaat cgttccttct acccaaactc tattttttcc cataaaaaaa
    41521 cttcctcctt tgaataaaaa agtcacaaag gaggaagcag ctttcgaaaa tagtcaaaca
    41581 gctgtttatt cacaattcct acgctcgcat aaccgataca ggtacgaagg gtttagaaat
    41641 agattcaatc tcagcccaat tggactcccc tttgtgagtt tatttattat ttattttttg
    41701 tttcaaacaa tggactaact ggtttgtttt catggatacg tttgattgca tctcccatta
    41761 gtccgccaac acttacttca tcgattttgt cgattttacg atcttctgga agatagatcg
    41821 agtctgtaac aactagacgc tcgatagctg aatcttctat tctttgtaaa gcagggccgg
    41881 ataatactgg atgtgtacat gaagcataca cactagttgc accagcttct ttcaaagcat
    41941 tggcagccaa tgtgatcgta cctgctgtat cgatcatatc atcgatcagt acacaagttt
    42001 tgcctttgac ttgtccaatg atattcatta cttctgcaac atttgctttt ggacggcgtt
    42061 tgtctatgat cgcaatcgga gatttcaaaa attccgctaa tttacgtgcc cgtgtgacac
    42121 caccatggtc tggtgaaaca acgacaacat catcgccttt gattcctttt tctaagaaat
    42181 aattggcaat aagtggcgca cccatcaaat gatcgactgg aatatcaaag aaaccttgga
    42241 tttggactgc atgaaggtcc aaagtcagca ttcttgttgc accagctttt tgaatcatgt
    42301 ttgctactaa tttcgctgtg attggttccc gtgcacgtgc tttacggtct tgacgcgcat
    42361 agccataata aggcatgact acgttgattg tttttgcact tgctcgtttc agtgcgtcaa
    42421 tcatgatcag caactccatc aagttatcat tgactgggct gctcgttgat tgaataacat
    42481 agacatgcga tccacgaata ctttcttcaa tgtttacttg aatttctcca tcactaaatt
    42541 gagtaacaga tgattttcct aactcgacgc cgactgctgc tgcaattttc tctgctaatg
    42601 ggcgattgga atttaacgca aaaattttta atcttgggtc aaagtaatgt tttgacatgg
    42661 ggacctccac tttctttttc acaactctag aattctacct aataaatagt agtcatattt
    42721 tttaaataaa tcaagtgatt ttgcaaaagt cttagtttag ataagggagt ttttttgcat
    42781 atccttcttt attgacttgt cttgctctcg caattgccag cgcatattct ggaatattgt
    42841 ctgtaattgt tgacccggca gcaatcgaac tgtttttagc tacctcgaca ggtccgatga
    42901 tattcgtgct agaaccaata aagctgtggt cgccgacagt cgtatgatgt ttgttctttc
    42961 catcatagtt gacgaagaca acaccacatc cgacattgat ttcttctccc agcgtagcat
    43021 caccaacata agtcaagtga ccgactttag ttcctttgcc gatttgagca tttttcactt
    43081 ccacaaagtt tccgatatgg acgttttcgc caatttcagc ttttggtcgt aaatgtgcat
    43141 aaggtcccac atctgcatgt ttcttgacat ggctgctttc aatgactgag ttttcaatga
    43201 cgacgtgatc ctcaatccta ctgtctacga tttttgaatg tgacccgatg acacaatcag
    43261 aaccaatgac tgtatttcct tggatttgta cacctgcttc gatcaatgtg tctggaccga
    43321 tttctacgcc tgcatcgatg tatgtcgttg ctgaatcgac aaagcttacg ccattgacca
    43381 tatgcatctg gttaattcgc tttctcatga tctcatttgc tttagctaac gcgatccgat
    43441 cattgactcc cattgattct tcaaaatcat ccgtttgata agcagcaact gtatggcctt
    43501 cttcttttaa gatttcgatg atatctgtta gatagtattc accttgagca ttgtttgttc
    43561 caactttgct taacgcatcg aacaaagctt cgttgtcaaa acagtaagtt cctgtattga
    43621 tttcttgtac aagagcttct tctggtgttg catctttttg ttccacgatt ttttctacga
    43681 tcccaatatg gtcacggatg attcgtccat atcctgttgg gttttctgct tgtgccgtca
    43741 agatcgttgc acttgcattt tttccttggt gatattcaaa aagattgttc agcgtttcag
    43801 tagtcaataa tggtgtatcg ccactgataa ctaacgttgt tccttttttt ccttccaaga
    43861 aagaagcagc ttgcaaaaca gcatgtcctg ttcccaattg ttctgcttgt aacgcatatt
    43921 tactgcgttc tcctagttgt gctttaactt gttctgctcc gtgtccaacg atcgtaatca
    43981 cttcatctgg tttcgtttca ctgacccgat taatgatatg ttctaccata ggtttaccag
    44041 aaacgggatg taaaacttta tataattttg acttcatgcg ggtacctttc cctgccgcca
    44101 aaataattgc ataacgtgcg tccaactgcg tcactcctaa atatagtttg ctgatttcag
    44161 tttatcccag tatacccatt ttttcaacaa aacaagtgat tttcttttat cccagcgttt
    44221 tctggataaa aaaatagata gaccataacg ggcctatcta tttggtaacc ggtgctctcc
    44281 tgccaactcc tcggtcacaa gtcacactac tcataaaaca tgaaaagctg ttttttgaaa
    44341 tcgtttcttg tgacttagag ttaaacggta ggcttacaac ctcttcatta aacgtttttc
    44401 aatcagctga ccttcggtat tagctcaata aacggcaaaa tatgaggagc aatttttccg
    44461 tttattgagc taatactcag gacaggacgc tgatttcaca acctctagat aaacggtgtt
    44521 caaaagccag tttctcggta ttaagccaaa tttatgaaaa aatgtggaaa gccattttca
    44581 caaaattttt cttactactc gaaactaagc ggctttttca caacctctta ttctgaaaaa
    44641 taatttcctg gcacaaccgt aatatttttc gtttgagtat ctacatcttt gacataaagc
    44701 agtgacgtat aatcatcgat ggcgcgatga ccgttgaatt ttgattcggc aaatacagtg
    44761 atgccaacaa gttctgattc gaattcttca atcaagctct tcattccgtt gactgttccg
    44821 ccgcctttca tgaaatcatc cactacaagg acacgtgaac cacgtttcaa acttctctta
    44881 gacagttcca tcttttcaat tctttcagaa gatccagaca catagttgac acttactgtt
    44941 gatccttctg ttatttttga gtcccggcgt acaataacga atggcgcatt cagataatag
    45001 gacacagctt gggcaatagg tacgcctttt gtggctacag tcattacagc atcgattttt
    45061 tcaccaaggt atttagaagc aatgattctt ccaacttgac gcagcagttc aggttctcct
    45121 aacaaatcag agagataaac atatcctcct ggaagcagac ggtcttgttc tgatagacgt
    45181 tctgctagag attcaatata ttttttcgcc tcttcatatg aaatttcagg gatgaacaat
    45241 acaccacctg cagcacccgg gattgtttcc aaggttccat accctcgttc tttaaatgtt
    45301 ttcttgatga ttcccaaatc ttcactgata gaagatttag cagattcata acgttcggca
    45361 aagcttgtta aggaaatcaa ttcatgcggg tgattcaata aatactgtgt catgtcaact
    45421 agacgttcac tgcgacgtac tttcacctat tccaactcct tttaagaaat tttatcgttt
    45481 tacattatat aagtttttct tcaaaaattc gagcatttta tgaaaaaata agaaaatagt
    45541 tcggtattta ttaaaataaa aagaagccta taaaaaattt ttcgttttta taaggcttct
    45601 tttctttata atttagttat tttttcttct gaaggcaacc aatattcgtt tgatgatatt
    45661 tacaatcagg aacaaagcaa taaagactaa tgtgattgtt gctcctggag gtgtatctag
    45721 ataaaacgag ctagttagtc ctgacagcat ccctagaaat cctacacaaa cactgatagc
    45781 aatcacgaca ttgaagcttt tgcctaatcg cataccgatt gctgcgggaa gaaccatgat
    45841 tgcggatatc aaaagtgcac cggcaatcgg gatcatcaca gcaatagcca caccagtaat
    45901 cacattgaac atcatcgaca tcaaatgaac gggtagccca tccacgtggg cggtatcttc
    45961 atcaaaagtc agaacataca tcggccgttt gaataaaaag aacaatatac cgatggcaac
    46021 gaataagatt cctaaaaaga tgacttgctc ccatgtaatg gtcacgatcg aaccaaacag
    46081 ataggattgg atacttgttg ctgaattccc tccgctcaaa ttcatcaata ctaacgctag
    46141 cgccaaacca ccagccatta aaatggcaat ggagatttct gaataggttc ggtagatcgt
    46201 tcgcagatac tccaatatca cagctgctaa tacaacgact agcatggtcg taagtgtagg
    46261 attaaggttc aaaaagaatc ctaacgctac ccctgctaaa gagacatgag aaagcgtatc
    46321 agccatcagc gattgtcttc tgatcactaa aaacacacct agcatcgggg cgattccggc
    46381 aatgaagata gcggcaagaa acgctcttct catgaattca tatgaaagca acgccattga
    46441 gaatcctcct ttctcaccag tcggatctgt ctgtccgcat actgtttgat atcttcatga
    46501 tcatgggtga tcattagaac tgatttccca tggacatgcg cactatgtcg gagaagacga
    46561 taaaattcat ttctggattc ttcatccata cctgttgttg gttcatcaag aacaaataag
    46621 tcagggtcag tagcaaaaat acgcgctaaa ctgattcgct gcttttgtcc gccagacaat
    46681 tcacctattc gccgatttcg catatcccac atccctacag cttctaaagc acgctgtaca
    46741 tgttgatgat ctttttcaga gagacgcttg aaccagcggc ctcttggata tcttcctgaa
    46801 cggactaatt cgatcaccgt actaggaaaa cctgcattga aagatgcaac ttgttgagga
    46861 atataaccga tacttaattt ttttccttct tgatttttct cagcaatctt tatcattcct
    46921 tttgaaggtt tcagtaatcc taacgatgct ttcaccaagg ttgacttggc tgctccattt
    46981 tctccagtta aaatgacaaa ttcacccgca tctacatgat aagagacatc ttctagtaca
    47041 ggttcatcat catagtaaaa ggtcaaatca gatatttcga tataacgcac cttacaacct
    47101 ccattctaaa acttaattga tactttcttt taaagctttc agattttttt ccatgacaga
    47161 aatataattt tcgcctgctt tgatttgttc attagtcaag ctttctaaag gattcaacac
    47221 ttctagcttc actcctgttt cattcgacaa tgtctcagct accttcgaag aggcattttc
    47281 ttcaaaataa atcactttga tgttgttttt cttcacaaat tcttttagct cagctaagcg
    47341 acttggtgtg ggttcctgat ctggtgaaac gcccgaaatc gctacttgtt ttaagtcgta
    47401 ttgattcgct aaataagcaa aagcagcatg ctgagtgaca aatgtgcggt ttgttgcatc
    47461 ttttagctca tcggagtatt tttgatccag tgcttcaagc tttttgatat aagcatcggc
    47521 attcttcgta aaagtttcct ttttatctgg atatttttcg cctaattctt cagcaatcgt
    47581 tctgacttct tttatagcta ataccggatc gagccaaaca tgtggatcgt attcatgtga
    47641 atgaccatgc ccttcttctg attcttcatg ttcgtctgct tcttgcgatt ctaaacggtc
    47701 gattccttta gctgcttcga tcatcaaggt ctgtttgcta tccactgaat cctttaacga
    47761 atccacaaaa aattccatgt ctgaactatt atacacgaaa acatctgcat cggaaatttc
    47821 tgctctttct tttgcacttg gttcgaaatc atgcggctcc gttccagcag ggatcaaaag
    47881 tttcacgttt ccttcatccc ctacgatctc ttttgtaaaa tcatacatcg gataaaaagt
    47941 cgtaacgatc gtcaaatcct cttttttgtc tgcttccttg ttcgtatttc cacatgctgc
    48001 aaacagtaaa gcacctatca ttaccgtagc tgtcaaaaga tattttttca tttatatgct
    48061 cctttcaatg aacaaatcgg aattttacga tttattaacg tgaactaatg tatcaaaata
    48121 aaaaaacaca gtcaatagaa atccatcaat ttctgattta agcatgtata ttcttgatta
    48181 aatcgtaaaa tggatgagtt gctgctcata tctagccatt tcactacaat aaaaaactga
    48241 agaataccat tttaggattc ctcagttttt catcacctat tttacttctt atattttatt
    48301 gcagggttcg tactaaataa acttcctcac aaaaaccttt taacccatta tatactctct
    48361 gcgctcttga ataatgttga cacaaggcaa aaacggttgg tccgcttcca ctcatcaatg
    48421 cagcatctgc tccgtacttg atcatacgct ctttgatttg atggatgact ggatgccgct
    48481 ttcccgttat atcttctaaa ctgtttccca tttttttgat catctgctga taatcttgct
    48541 ctcggatggc ttcagcaagt ccgtggatgt cttgatgttg gatggcttgc gtatctactt
    48601 ctctaaacac tgtacgtgta gagacactca ttcttggttt gaccaacaca acccagcact
    48661 gtggcataga aggtaatact tggatttctt cccctttgcc accgacaaat gccgtacttc
    48721 cgtagacaca gtaaggaaca tctgtaccga cttccaaacc gatttctgcc agttcttcta
    48781 acgaacagcc cagattccat aattggttga tccctcttag agcagctgca cagtctgtac
    48841 ttcctccgcc taatccagct gctactggaa tattcttctt aacaaagatc ttgacaccgg
    48901 ttttgatatt gtatttattt tttagcaata aagcagcttg ataaacattg ttccgttcat
    48961 ctaccggtaa aaatgcttta tttgtttcta caatgatttt gtcttctgtt atttcttcaa
    49021 aaaatagatg atctgccaag tctacgctcg acatcaccat ttccaactca tgatacccat
    49081 cttgccgtct atataataca tccagtccta aatttatctt ggctggcgct ttttcaatca
    49141 attccatcct ctcacccatt cgaaaagtct aagtcgcaag tattctatca tagggaaaaa
    49201 taaaagtata gcttatgtct gcctagtggt tgattttgtc atcgtttcaa cagctttcac
    49261 agaattttct cttcataatc caaacaagtt ctagtgattc ttataattct gtgagcactt
    49321 cttctgccaa actcggaaca tttccttttt cttttcctat cagactgagt agctgcatgg
    49381 tagcaaatcc gaaattactt cctttcctat aagcaaaata acgtccttcc caatgatcga
    49441 catattttaa tttcttttca taagcagact ggaaggaata gaaaaaatta ccataattat
    49501 atacgatatg catgactttt tcttgaaaga aagaaaaatc tgtttctcca acattagcta
    49561 atggagctaa gcctagattg gcttccgagt agcccatttt ctcgtataca ataaacagat
    49621 tggctaacag atagtcagct aattcctcag attctttagg taagacccgc aacaaatcat
    49681 atcccgcctg cttcttcgtc atcggctgag cggtgatgaa gccaacgact ttttgatctt
    49741 tacggacaat accgacaccg ctagataata catatgattt atcaaatcgt cccacagaga
    49801 agtatttttc tcgtgcacct tgaagccatt tttgtgaaac ttcatttaca gcttgatgta
    49861 attcttccgg cagttgatcg taccaagtaa aatggtatcc ttctttcatc aaacgttgat
    49921 attcaagttg ctgactcagc cgagacaagt cttctgttgc tagatcaaca atccctgctt
    49981 cacctacttt cgtgaagtga aaacccaatt catgaagcat cactacgtag ctttctgata
    50041 tcttataaaa cgcaagctga tagcctaaac aatctgcttg tttcataaac tgattcgttg
    50101 ctgcccgcat cattttagga ttgccaactg gatctcctaa aacaaagcat ttgtttcctt
    50161 tgatctgata accaaaaacg acttgatctt ggtcgtcttc ttggtaataa aaataactgt
    50221 aacctgacaa gcgaagctga tggcttgtag ctgtgcctcc gtatgtttcc aataaacggt
    50281 caaaacggtc tttttcgtac tcactgccaa gcttcgtagt atcttcagct aaatattgat
    50341 aaagcgccac taaagctagc aatgagatgc ccaaaccaat aagccctgag aaccacacat
    50401 catctgaagg aaacaaaata aaatgatttc ctgttattcg accgactaaa aagcgtccgc
    50461 tgtgatagcc tgcaattgcg taaacgataa acaaaaagcc gaacaagcta gcatcaaaga
    50521 ttatagctcc ccaagaataa acgaattttg ttcgataaaa ttcttttctg gataaccaca
    50581 cagctaacag aatcaagaca tataccaata tcaactgcca agataacgta cgtgtgattg
    50641 tatttaaaat accaaaagat agtaaagcaa tcgtaggcag aaatgccttt ttgactttta
    50701 ctgaaagtgc tctagcaagg ccgagtaata aaaagccaac caatagattc actgtctgat
    50761 ctaaaaaatt gaatgagaac ggcaataata cttgaaatag ccgactgatt gcagacagat
    50821 tagtgattgt tgatagaagt accatcatga tccccgcaaa atagacagca cttacgagca
    50881 cgatatgcgc aaccttttgg aaaaacagtc gcggaatgtt atctaaaaat cgattgattt
    50941 tgactcctgt atgtgtgatg aacaatagaa gtcccgtcat aaaaggtaga acataataaa
    51001 acaaccgata atataatagc caaactactg ctacatcttg ccgaacagac aattgactca
    51061 ttcctaagat catcaaaacg tcaaaagtcc ccattccacc tgggaccatc gtcagcattc
    51121 ctatcaatgt agcaatcatg aacataggat agatcgaaag catcgaaata tctattctca
    51181 tcaacttgcc gatgatcaaa aataccgcaa gggctcccgt ccattgtcca aaggatgcca
    51241 gtagcagacc aagcaagcct tttggataaa actcgaagaa caatgtcttt ctctttagat
    51301 aagcaaaaaa gaaaatgact ggtgctaaaa aactaccgcc gaaaagccag atccaatagc
    51361 ttcgaaaaat actttctgac tgaataaaaa agacatcaat aaatgtaaga aacgaccata
    51421 cagacaaacc agtcagcata aatagtgcga cttttgatac agtggctaaa accatttttc
    51481 tatttgtctg ctttccataa aaactagccc gcagacttgc tcctaccaca ccaccaaaac
    51541 cggcgagatt gttgatcgtg tttgttaccc acgcagcaag aagaaactct tttctttcca
    51601 tttttggttt tccttgtttt tctaagactc tgatcgtcac ccaatcatac aacaacatcg
    51661 gagtgacacc cagcagtcca gccagaatca tgagcaggat cgtcatgcgg ctttgttgtc
    51721 ccatcctttg ccaaatatct tgccaactca tgccattagc aatatttgcg acttgatttg
    51781 ccacaaagac taacacggag ccgaaaaaaa tcagttttaa aatcagacta tgttccttta
    51841 tccattgcag catcaagtat cgtttatttt tcacattttc ccattcctaa cttgtatact
    51901 tttgtgtcat accccaatgt tatcttattt attttaattt ttccacttta gacctgttct
    51961 ttgcttgcga tgatagaaaa agaaagatat cctaatgcta aaggagagga taacatgaaa
    52021 gtaggattta tcggcacagg gaatatggca caagctatta ttgatggttt attaaaaaaa
    52081 ggaacagtct cgaaagaaga ggtgttcgtt tccagtggac attttgaaaa tgcacaaaaa
    52141 tttgctgctg aaactggcgt ccatgcatgc aaaagtaatc aggaagttgc atcacaatca
    52201 gatatcgttc ttttagccgt gaaaccaaaa atcattgaaa aagtattgga agaactaaga
    52261 gaatatagcc agaaagtctt attcatttct attgcttcag gaaaatcatt aacagattta
    52321 gaaacagcgc ttgaagatcc tcaggcctcc atcgtacgtg tgatgccgaa tgtcaatgtc
    52381 agcgtaggag caggcgtttc tgcgatttgc aaaaatgaag ctgccacgga ggaacagctt
    52441 cagcaagcta cgatgatttt tgaagcaatc ggcagcgtct atcctttagc agaatcagat
    52501 ttcagtacat tcattggcct tgctggcagc tcacccgcat tcgtttacat gctgatcgat
    52561 gcgatgggac ggactggtgt actgaatggt ttgtccaaac agacagccac tgagattgct
    52621 gcaaaagcaa ttatgggttc ttgtcaaaaa ttcctttcaa gtgataaaaa tccatgggaa
    52681 cttgtagacc aagtttcttc tcctggcggt acaactgttg caggtgtagt tgccttagaa
    52741 gaagcaggat tcatcccagc aatcatcaaa ggaatcaata cgacgatcga gaaagatctt
    52801 gagatgttga ataaaaaata atgatagcaa tgttttttcg taccttacaa aaaaagaaga
    52861 gctgtggctt ttgccgcggc tctt
//
LOCUS       DAFBVQ010000012        50590 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.012, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000012 DAFBVQ010000000
VERSION     DAFBVQ010000012.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 50590)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 50590)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..50590
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.012"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            131..505
                     /locus_tag="LLC22_000889"
     CDS             131..505
                     /locus_tag="LLC22_000889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBK5434185.1"
                     /translation="MYLKITEQAQERLQKYIDEGATVILDLDDGVGEYSKMGVCSLDT
                     SFRLLLLDKEQRKNDYKLQLDSDIGDVYIKDYSKMYMDEHMTLSLDPRLGVFTLESPS
                     GSLDSHVQLVDLRPEKFSGIKQ"
     gene            complement(619..1248)
                     /locus_tag="LLC22_000890"
     CDS             complement(619..1248)
                     /locus_tag="LLC22_000890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5434186.1"
                     /translation="MKIVFLHGLGQDEQSWKDVISYLPNSYSCKSLSLFNHLNSTDTA
                     TLDDLTKYIEVQLNQIKEPFILCGLSLGAVIALNYLATPSPYLKKVVLVAPQFESPNR
                     LLLTFQNIYFYCVPSKIFEKLGLSKKQTLTLLRSLETLDCKKQLRTSRLPKLILCGTK
                     DHANKPAAKRLYKLSTNGRLLFIKNGKHELNREKPEIMAQAMRSFIENS"
     gene            complement(1382..1454)
                     /locus_tag="LLC22_000891"
     tRNA            complement(1382..1454)
                     /locus_tag="LLC22_000891"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(1419..1421),aa:Thr,seq:ggt)
     gene            1668..1741
                     /locus_tag="LLC22_000892"
     tRNA            1668..1741
                     /locus_tag="LLC22_000892"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1702..1704,aa:Asn,seq:gtt)
     gene            complement(1879..2043)
                     /locus_tag="LLC22_000893"
     CDS             complement(1879..2043)
                     /locus_tag="LLC22_000893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434187.1"
                     /translation="MKNLIAGGFLFVGGGILMNTDNFGNVIPFLGAACALIGVGMLIY
                     FVFSDDGKYG"
     gene            2338..3666
                     /locus_tag="LLC22_000894"
     CDS             2338..3666
                     /locus_tag="LLC22_000894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C1 family peptidase"
                     /protein_id="HBK5434188.1"
                     /translation="MKAITPDMTTKFNKQFQANIKQQALQRAVVKNGITASAENVSAH
                     VENTPVFSIDLATGKVANQMQSGRCWMFAALNTFRHKMLNQFHLKEFELSQNYTFFWD
                     KYEKANYFYENIIATGKEAIDSRKVAFLLATPQQDGGQWDMIVSLFQKYGVVPKSVMP
                     ESANSSNSRDLNNYLNKLLRKDAVVLRKMVAQGETLDAIEEKKEEMLESIYNFLAISL
                     GTPPKEFDFEYRDEEKNYHLDRGLTPQIFYDKYIGVKLDDYVSVINAPTKDKPFNRSY
                     TVEMLGNVVGGKEVKYLNVDMETFKKLAIAQLEEGESVWFGCDVGQSSTRTSGIMALD
                     AYSMDDLFDTDFTMTKAERLDFGESLMTHAMVLTGVDLVDGQSTKWKVENSWGEKVGK
                     NGFFVMSDAWMDEYTYQIVVRKDLLTKEQLNAFNEEPIVLSPWDPMGALA"
     gene            3868..4701
                     /locus_tag="LLC22_000895"
     CDS             3868..4701
                     /locus_tag="LLC22_000895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructosamine kinase family protein"
                     /protein_id="HBK5434189.1"
                     /translation="MDIQTVLSDLKLNGKVIPVVGGDVNQTYRIKTEHRAYFLKIHPN
                     VKKGFFEAEVDGLKELSAFVRVPDTYMLGETSEGAYLLMEWIEPGKGDQRDLAAALAN
                     LHQQTAPQFGFRKDNYLGTLVQKNSFEEDWWTFFFKDRLESQISLAEETNRWNVQRQE
                     KYLRFKERVLKSVEPKKITPRLLHGDLWSGNVFFDQQGHPVFVDPAVSYGNREQDIAM
                     SQLFGGFRPEFLDAYQTIFPLEKGWKDRLPIYQLYYLLAHLNMFGESYGSQVDQLLEN
                     F"
     gene            4717..5454
                     /locus_tag="LLC22_000896"
     CDS             4717..5454
                     /locus_tag="LLC22_000896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-[acyl-carrier-protein] thioesterase"
                     /protein_id="HBK5434190.1"
                     /translation="MAKKYTKKHEVSYYECDINQTMTFPSMLGVVIKTSEDQSDQLGR
                     GSEFVNSFGLTWVITNYSMEINRLPRVGEVISVTTQAMEYNKFFCYRNFWIHDEDGKE
                     LVKIESVFVLMDFVNRKMSSVNEEIIAPFESEKIKKIKRQEKIEKIDSGFMLPYRVRF
                     YDIDSNQHVNNAMYFNWIIDVLGYDFLTTHVPEKVIIRFDKEVEYGNEIESHFEQIPI
                     ENGVKTKHEIRMQEQLYCEANIIWKNK"
     gene            complement(5609..6577)
                     /locus_tag="LLC22_000897"
     CDS             complement(5609..6577)
                     /locus_tag="LLC22_000897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparaginase"
                     /protein_id="HBK5434191.1"
                     /translation="MKKILVLHTGGTIAMKENMLTGGVSPDVANPLLDAEITIPKHVE
                     LLVEDIFNLPSPHIMPSHMLVLKERILSAYASGISGVVITHGTDTLEETAFFLDTTIG
                     NKLPIVLTGAMRSSNELGSDGLYNFESAIRVASCEEALDKGVLVVMNDEIHSARYVTK
                     THTTNVATFRTPTLGPIGLVTKNRILFLQELLETKRLDISAVDGTIPIVKAYAGMQGD
                     LLEAIAHTKVDGLVIEALGAGNLPPQALAALEKLLVQKIPVVLVSRCFNGIAEPVYDY
                     EGGGKELEKMGIIFCNSINSQKARLKLLIAVNYGLSGEELISFIQN"
     gene            6809..7642
                     /locus_tag="LLC22_000898"
     CDS             6809..7642
                     /locus_tag="LLC22_000898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372832.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF72 domain-containing protein"
                     /protein_id="HBK5434192.1"
                     /translation="MIRIGLTSFKEHDKLTGKKNNTLYEYAGFLPLVELDTAYYGIPR
                     KSSVENWISEVPESFRFVVKVYQGISGQGDWKPYYQTEEEMIAHFLDVMSPMVDAGKM
                     FCFLVQFPSSFKCTKENVQYLRKLRKWFEGYPVSIELRDYSWYSDEFLERTRNFMSRA
                     AFSLAIIDEPQLLNTTIPFDPFVTNPNFALFRFHGRNAQGWQANDKEWRKKRTLYRYS
                     EKELQELAHEVKVVDSKTKEVGVIFNNNSGGDAAENALALQKILNIKPDGLNPTQMDL
                     F"
     gene            7676..8515
                     /locus_tag="LLC22_000899"
     CDS             7676..8515
                     /locus_tag="LLC22_000899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5434193.1"
                     /translation="MIKAIFFDIDGTLVTNRSKALESTKQAIEYARKNGILCGVATGR
                     SPVKIKEIIDELELDMYVVYNGQLVFTADRTIIDHPFEQKVLEHIVEFADENHRQIVF
                     GARNRLDGSTTMLLGQSIFIKRLVSFLPRKFPVRLMKKILQVFSPHRQKDRYETLEIL
                     KEPIYQCILLSPESEQKKLEHRFPECTFQRSNTYTVDIIPKGGSKLLGIQAFANAVEI
                     EMEEIMAFGDHYNDIEMLKGVGIGVAMGNAQIEVKHAADFVTQSNEEDGIYEGLKHFG
                     LIY"
     gene            8541..9101
                     /locus_tag="LLC22_000900"
     CDS             8541..9101
                     /locus_tag="LLC22_000900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK5434194.1"
                     /translation="MEAETPFQKVETFHKTFDPRRPEIPTAFTENEAHTRAAFKIEEL
                     VEFVAATSPNKEQLHEAVMLLHEALDKAEEKILGKTQWGSDPLVEQVDALTDILYFTY
                     GSFSLLGIVPDRIFEIVHQANMGKLFPDGKPHYDPVTNKVLKPENWQMEYAPEPKIAA
                     EIQRQIQEAIAKKKSADIGMCTNEKE"
     gene            9300..11021
                     /locus_tag="LLC22_000901"
     CDS             9300..11021
                     /locus_tag="LLC22_000901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septation ring formation regulator EzrA"
                     /protein_id="HBK5434195.1"
                     /translation="MGNNVIIGIVIAIIIVAIVVFLVSYLMKKKNQDRLDALEKRKEE
                     LFDLPVIEEVDDVKKMHLVGQSQNTFREWSQKWNDISTSSFAELESQIFEVENLNESF
                     RFLKGKKAVVEAEATMDQMEKQVTEIREGLKELRETEERNSLAVQQALDVYEELKEKV
                     REDEHEYGPALFELQKQIKVIEKEFTQFVTLNTSGDPVEAREVLDKAEKHTYEVEALM
                     KKIPPLYEELHTTFPEQLEEISDTYEKLMEEQYVFPEEDLAEDIAKVSRRIENSLANL
                     EKTEVETVEFENRETADLIDSLYDILEREMEAQRYVKTNQSTIAEYIKHTTKNNRQLL
                     IELDHTSQSYTLNHNEIGRVRGFQTEVEEMERQNEQMIPQIRQHEIPYSEVRTFYKTV
                     FKVLEDIEKQQVEIDDSLHELRKGEKEAQEKIDTFEFKLRSLKRFVEKQRLPGLPNDY
                     LEFFFVATDRIEELSVVLNKIRVNMEEVNRLVALCEEDLELLDKKTHDLVDAAALTEQ
                     MLQYANRYRHTHEEVREAIDKSYYLFNKEYHYQEALDEIGTALERVEPGAFKRIEDFY
                     FNHPDLV"
     gene            11186..12328
                     /locus_tag="LLC22_000902"
     CDS             11186..12328
                     /locus_tag="LLC22_000902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK5434196.1"
                     /translation="MIYFDNSATTPIFPQSLDAYVKTSQRIIGNPSSLHDLGNQANRL
                     LQQARKQIADLIHVEPEEIYFTSGGTEGDNWVLKGTMIEKREYGNHMIISGVEHPAVS
                     ETAEQLKELGIEVSIAPVDKRGFVRVDELKELIRKETVLVSVMAVNNEVGSIQPIQEI
                     SDLLDDFPKIHFHVDAVQAIGKVPFSQWLTERVDFATFSAHKFHGPRGTGFIYWKKGR
                     RLAPLLTGGGQERNQRSGTENVPGIVAMVKALRLSLEIKEQKPEQTQRLKVALINALK
                     TYEKVTIFSEGTDYAPHILCFALKGIRGEVLVHALEEKQIFVSTTSACSSRKHMASST
                     LHAMHVPNDLATSAVRISLDENNSLAEVEQFMIIFKQLYKKFSAIN"
     gene            12344..13555
                     /gene="thiI"
                     /locus_tag="LLC22_000903"
     CDS             12344..13555
                     /gene="thiI"
                     /locus_tag="LLC22_000903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391639.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA 4-thiouridine(8) synthase ThiI"
                     /protein_id="HBK5434197.1"
                     /translation="MKYSEIMVRYGELSTKGKNRKSFIMQLAQNVRQALKDFPEIKIH
                     ADRDRMHLLLNGADGQLVIPKLAKIFGIQNFSPSIRVEKDVEVLKQAVQDIMKEIYTG
                     KETFKIIAKRSDHQFELTSNELNQTLGNAVFDIFPHIQVQMRQPDIPLRVEIRRDGAY
                     LSYETIKGAGGLPVGTSGKGMLMLSGGIDSPVAGYFAMKRGVEIEAVHFASPPYTSEQ
                     ALQKAKDLTAKLAPYVGTIHFIEVPFTEIQEEIKKSVPQGYWMTITRRMMLRLTDEIR
                     RIRHGLVILNGESLGQVASQTLQSMVAINEVTNTPIIRPVATMDKLEIIEVAEQIDTF
                     NLSIQPFEDCCTIFAPPQPKTRPQLEKVHQYEERLAIDEMIQRALAGLKMEEIQAESS
                     NEKTEEFSELL"
     gene            14128..14775
                     /locus_tag="LLC22_000904"
     CDS             14128..14775
                     /locus_tag="LLC22_000904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-sensing transcriptional repressor Rex"
                     /protein_id="HBK5434198.1"
                     /translation="MREKTDTLPKATAKRLPLYLRYLKMLDDSGISRIKSNEFSEITQ
                     IPSATIRRDFSQLGELGRSGYGYDVPFLIDVFNNILNTKEEKRIALVGYGNLGKALKH
                     NNFRRNENLNIVCVFDNDPALINRVIDGEMIYPIDRFAEIAKAKNVTVAISTVPSKYS
                     QSAIDEIVKGNVTAILNFAPDRVTVPAYVNVQYIDLTTELQTLIYFDENYSEVFS"
     misc_binding    14904..15120
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            15168..17813
                     /locus_tag="LLC22_000905"
     CDS             15168..17813
                     /locus_tag="LLC22_000905"
                     /EC_number="6.1.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="valine--tRNA ligase"
                     /protein_id="HBK5434199.1"
                     /translation="MTEENNLSTKYNPQEVEAGRYQHWLEQDLFKPSGDKKAKPYSIV
                     IPPPNVTGKLHLGHAWDTTLQDMLIRQKRMQGYDTLWLPGMDHAGIATQAKVEAKLRE
                     QGISRYDLGREKFIDQVWEWKEEYASHIREQWAKMGLSLDYSRERFTLDDGLSEAVRK
                     VFVTLYEKGLIYRGEYIINWDPQARTALSDIEVIHKDIEGAFYHMSYELADGSGVVEI
                     ATTRPETMLGDTAIAVHPEDERYQALIGKKVILPLVNKQIPIIADEYVDMEFGTGVVK
                     ITPAHDPNDFEVGNRHDLPRVNVMDDDGTMNELAGKYAGMERFAARKAIVQDLKEIGR
                     LIKIDTMIHSVGHSERTGVVVEPRLSTQWFVKMAPLAKKAIDNQETDQAVEFFPPRFN
                     QTFLRWMENVHDWVISRQLWWGHQIPAWYHKETGEMYVGMEAPADSENWVQDPDVLDT
                     WFSSALWPFSTMGWPDTESEDYKRYFPTSTLVTGYDIIFFWVSRMIFQSLEFTGERPF
                     ENVLIHGLIRDEQGRKMSKSLGNGIDPMEVIEKYGADALRWFLSNGSAPGQDVRFSYE
                     KMDASWNFINKIWNASRFVIMNIEGMTVEEIDLSGEKSVADRWILTRLNETIERVTEL
                     FDRFEFGEAGRQLYNFIWDDFCDWYIEMSKEVLYGDDAVSKQTTRSILVHTLDQILRL
                     LHPIMPFVTEEIWEHIPHQGNSLVVAEYPVVRPEFDDETASKGMEVLKELIRAVRNIR
                     SEVNTPLSKPITLLIKTNDAKIDQFLVENTSYIERFCNPEELTISSEITAPDLAMSAV
                     LTGAEIFLPLAGLINIEEEIKRLEKELEKWTSEVKRVQGKLSNERFVSNAPEEVVEAE
                     RAKEKDYLEKQTAVKERIESLRTIQ"
     gene            18123..19436
                     /locus_tag="LLC22_000906"
     CDS             18123..19436
                     /locus_tag="LLC22_000906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional folylpolyglutamate
                     synthase/dihydrofolate synthase"
                     /protein_id="HBK5434200.1"
                     /translation="MTIEEAIEWIHSRLPFGSRPGLDRVEALLEVVGHPERKVKTIHI
                     AGTNGKGSTVAYLRSLLEEAGLTVGTFTSPYIETFNERIAINGKSIPDNDLIQLVKKY
                     QPLIKQLDQFEAVAGITEFETLTAMAFDYFLMKKVDVAIIEVGLGGLLDSTNVAVPML
                     TGITTIGLDHTEILGDTIEEIAAQKAGIIKQGVPVVTGNIAPEAFTVIQQTAKAKNAP
                     LYVYGENYKINYLHPDEMWGEVFEFFNEIGKIPQLTTPLLGQHQAENAGVAIELYFVY
                     CQLEKLPFREKDVLKGLKKSRWPGRMERLSNEPLVVLDGAHNTHAMNRLVENLKKEFK
                     GYQINILFSALRTKNVREMLERLQQVPNVHIYLTTFEHPKAIELSEVSDLASERVSIV
                     SLWQFGLADILEKMTNEDVLVVTGSLYFISEVRHLLIQLGGDHEV"
     gene            19426..20079
                     /locus_tag="LLC22_000907"
     CDS             19426..20079
                     /locus_tag="LLC22_000907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5434201.1"
                     /translation="MKYNAVIFDMDGLLFDTELVYYEATQVVADKMGFPYDKDLYLKF
                     LGVSDEEVWANYHMIFSEFGKTSVQRFIDDSYQETLERFSQGAVQMKPGVLELLSFLE
                     EHQIPKVVASSNQRAVIELLLKKNNLFERFETIVSAENVQRAKPDPEIFLLANQKLGT
                     AKKETLILEDSQNGILAASAAEIPVVMVPDLLPPSQELIKKTAGVVSSLHEIPALLK"
     gene            20134..20805
                     /gene="radC"
                     /locus_tag="LLC22_000908"
     CDS             20134..20805
                     /gene="radC"
                     /locus_tag="LLC22_000908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadC"
                     /protein_id="HBK5434202.1"
                     /translation="MGKRLIKEVPTSSLPRERMEIYGAEALSDQELLAILLRTGQHPY
                     SVMSIAGNLLKTFGGLASLRQATLHELEEIRGIGRVKAIEIKALIELGRRIQTDHERA
                     APPVRTSYELAQQLILEMKDHKQEHLVCIYLDTKNQVILKKTVFIGSLNQSVAHPREI
                     FHYAVRYCAARIVLAHNHPSGIYKLVHINYIRKFTVILPSGNTIMLSIIERHNAFFSS
                     SEDSL"
     gene            complement(20700..22052)
                     /locus_tag="LLC22_000909"
     CDS             complement(20700..22052)
                     /locus_tag="LLC22_000909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5434203.1"
                     /translation="MKRVALYMRVSTEQQAKHGDSLREQKETLYEYIEQHKDLKVVNE
                     YVDGGISGQKINRDEFQKLLQDVKENKIDLILFTKLDRWFRNLRHYLNTQEILEKHNV
                     SWNAVSQQYYDTTTAYGRTFIAQVMSFAELEAQIDSERIKAVMANKIAQGEVVSGKTP
                     LGYSIENKKLVINDDAPIVIDIFNYFLSSGSLRKTVYYLGSQYGIVRDYQSVKNMLTN
                     KKYIGELRNNKNYCPPIIDKKLFYAVQKALPKNLKTNAKRDYIFKGLLKCSDCQGSVA
                     GQTIKARYKKKDGTESIYERTCYRCVKRRNNKLRCTNKRAFYEKNLERYIFEATKQKF
                     EQIQINYSKKQPKIIKKKNSKKNIENKLDRLKKAYLNEVIDLEEYKKDREALMKELNE
                     IEVEPAKIDIKNVEFILSKEFDEIYKESSEEEKNALWRSIIDNIIVFPDGNITVNFLI
                     "
     gene            complement(22118..23407)
                     /locus_tag="LLC22_000910"
     CDS             complement(22118..23407)
                     /locus_tag="LLC22_000910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBK5434204.1"
                     /translation="MGVLLFLVGIVLIIMGSSKLSEAKKLKDKTSALESKVKEYSQEL
                     NARETFISEKEKNISKLNKNLSTLENKIDILNAESQRLDDEINQKYDTSLVTIYKSVI
                     IPNIDETSSSEIKNKLSLLKIKEKDFILDGAINIPSYLNNREANNIKKKMLIPLESEI
                     TGLLNKLTISNVDSTREKIIRTFDKINKLFKNDEAEFKKELLELKLQELELNYSYIVK
                     VNDEKEQQKAIKEQMIEEEKVRREIEREKKRIDKEERQFNSEITKLMAYMQKASADVE
                     KELYADKIKELEEKLRELETVKEDVLQRELNTRAGYVYVISNIGSFGEDVYKIGMTRR
                     LEPMDRIKELSSASVPFEFDVHAMIFSEDAPTLENQLHSHFRKNEVNKVNQRKEFFKV
                     SLDEIEKVVLENYNGTVSFTKLAQAEQYRRSLELTDV"
     gene            complement(23494..24198)
                     /locus_tag="LLC22_000911"
     CDS             complement(23494..24198)
                     /locus_tag="LLC22_000911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LexA family transcriptional regulator"
                     /protein_id="HBK5434205.1"
                     /translation="MFAENLKFLREKYNIDQQELAEKLGRKSSSSISEWEKGKYTPKL
                     KTLNEIAKIFNVDIDDLMNIDLSISNQIYNILPIYNQLNDENKVATYEFASNRLEEQK
                     QENVLDFPKKEKIPTVHNSASAANPTELTYGDTVVEEEEFERVPSAADFAVPIIGDSM
                     EPVIRNGQFVFVKEQPDVEDGEIAIVELGGDGVTCKEIYKDYENQTIILRSINDLYED
                     RIVSPEQIRIIGKVVF"
     gene            24398..24664
                     /locus_tag="LLC22_000912"
     CDS             24398..24664
                     /locus_tag="LLC22_000912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303266.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5434206.1"
                     /translation="MDTAKKEKYTLRQLRALKGYSKEELSRKSKVTSRTIFIYENDVD
                     KMRNGKYATLEKIAKALGVRVSDIFLDPDSEKPKSITGETKQVS"
     gene            24677..24835
                     /locus_tag="LLC22_000913"
     CDS             24677..24835
                     /locus_tag="LLC22_000913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434207.1"
                     /translation="MEEKNIKVPTLEEYTKIVVETDEQNPKTIAVITANDIESCEGFR
                     VRMTPRYD"
     gene            complement(24832..25062)
                     /locus_tag="LLC22_000914"
     CDS             complement(24832..25062)
                     /locus_tag="LLC22_000914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBK5434208.1"
                     /translation="MGKNQWVSPRNGKWAVRGEGNSEDTKLFDNKSDAVEYGKKISKK
                     QQSEFIVQKKNGQIQSKDSFGNDPIPPRDKEH"
     gene            25134..25289
                     /locus_tag="LLC22_000915"
     CDS             25134..25289
                     /locus_tag="LLC22_000915"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434209.1"
                     /translation="MSNKPKITLNGTPNLQRLADEMARIRSRHWGVTVVATIIEQKEK
                     PTQPASK"
     gene            25446..25601
                     /locus_tag="LLC22_000916"
     CDS             25446..25601
                     /locus_tag="LLC22_000916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434210.1"
                     /translation="MKEESKIGILNENNYTRLIIETEEGEKVAEVTLTDATPADGYRI
                     RLTPKYD"
     gene            complement(25598..25822)
                     /locus_tag="LLC22_000917"
     CDS             complement(25598..25822)
                     /locus_tag="LLC22_000917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBK5434211.1"
                     /translation="MGKNQHVVPNSNGGWNVKGAGNSKATAHTNTKSEAVKIAREISK
                     NQGSELFIHGRDGKIQSRDSHGNDPHPPKG"
     gene            26089..26424
                     /locus_tag="LLC22_000918"
     CDS             26089..26424
                     /locus_tag="LLC22_000918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434212.1"
                     /translation="MNKKIENLIEELKRECQKQGVSIICTAQKEGELKSLVYGETTEI
                     LLCLAMQEEHLDENLPLSAHIMRRIAVDAYEQAKNEEENQPSNHTFVINNKEDLADVM
                     TRILKGEFQ"
     gene            26657..27598
                     /locus_tag="LLC22_000919"
     CDS             26657..27598
                     /locus_tag="LLC22_000919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629347.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqaJ viral recombinase family protein"
                     /protein_id="HBK5434213.1"
                     /translation="MSKSTLEMSHQEWLEDRKRGIGGSDVATVLGLNKYKSPYQLWLE
                     KTGQIELKDLESEPAYWGNVLEEVVAKEFQERTGKKVRRRNQVFEHPLHPFLRANIDR
                     EVVGENAILECKTANQFLGKEWEGEEVPLSYLCQVQHYMNVLNKDYCYIAVLIGGQKF
                     IWKRIERDQELIDTITEQLVEFWETNVLGGIEPVIDGSGATADFLKEKYADVEENQTA
                     LPSRFDELIEQKRELKRTKKEIESSIRQVDNEIISELGKREASIGITQRNIISWKLVR
                     TRRMNTKKLAEKYPDVANDEEIYNVTESRRLTEKEIK"
     gene            27600..28490
                     /locus_tag="LLC22_000920"
     CDS             27600..28490
                     /locus_tag="LLC22_000920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecT"
                     /protein_id="HBK5434214.1"
                     /translation="MATNESLKNQLAEKPQKQVAPGQLGLKALMNTPTMRKKFEEVLH
                     DNANAFMSNVMTLVSNDSYLADSEPMSIMSGALTAATLNLGLDKNLGYAYLVPFNSKN
                     KQTGKWEKKAQFMLGYKGYIQLAQRSGKYKALNVIEVYEGELKSWNRLTEEFEFDPNG
                     RTSDEVIGYVGYFELLNGFKKTVYWTKQEIEAHRIANNKDRDKTKLSGVWASDYNAMA
                     RKTVLRNLLSKWGILSIEMQEATTSDERVQRVQEDGSIIAETEVEEDIPERKEAEVIS
                     EENEDVQTGLFDASNPPLNK"
     gene            28533..29333
                     /locus_tag="LLC22_000921"
     CDS             28533..29333
                     /locus_tag="LLC22_000921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBK5434215.1"
                     /translation="MNTGYVKLHRKVMNSFVWTNPYMYKLWSLCLMKASHENRKILFN
                     GKEIQVNSGEFVTGRDAITSEMNEGVKREHQVNSGSVWRWLKQFEKNGMLNIKSTTKY
                     SVISIKNWSLYQSSEQQMNIKRTTSEQQVHTNKNEKNYKNEKNNKTSSSQPRKKRVYD
                     TDSVYYILAEELFKQICQNQEIKKPNLQSWADNIRKMIEIDKRTENQVRGMIEWSQHN
                     VFWASNILSAKKLREKYDTMAAQANRDYKTKQTKTLEYEKFSTDELPI"
     gene            29348..30199
                     /locus_tag="LLC22_000922"
     CDS             29348..30199
                     /locus_tag="LLC22_000922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5434216.1"
                     /translation="METVGEIMEKLIQKVLVQRGECPECGQPLYGWRTKNPDGSERCK
                     PTCMQCGYKALRVQEDLQTERIYNESLKARAINFFKGGSVVPNQALFDCTLQNYQIVD
                     QETRQAVEVTKRFVNSVLLGNPSHLVLTGKQGTGKSHLAMAAAWEVLKRSNYDKKILF
                     IGLQEMLDQIKFSYNNPELRKTIEGSLIADIKTADLVIIDDIGSELGKDASDSRAFGI
                     NTLNSFLDARQNLATIITTNLLGEELKKAYGTRTISRMFVNSDGFTMVFSQTADKRIK
                     PVKGSIA"
     gene            30196..30555
                     /locus_tag="LLC22_000923"
     CDS             30196..30555
                     /locus_tag="LLC22_000923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1064 domain-containing protein"
                     /protein_id="HBK5434217.1"
                     /translation="MNKYRNKKTVHRGIKFDSIAEAEYYDLALWQAEANGWKVKLQER
                     FELMPKFELEGKKYRKIEYIPDFTFYKSGKLVKVVDVKGMQTKDFKIKAKLFCHQYQV
                     PLILAKKYRNTFKEERF"
     gene            30570..30731
                     /locus_tag="LLC22_000924"
     CDS             30570..30731
                     /locus_tag="LLC22_000924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antitoxin"
                     /protein_id="HBK5434218.1"
                     /translation="MTTEEVIQMRIRSLRREIDDLERTKAVMVNETARKAIDLHIENL
                     RREIRRLEE"
     gene            30728..31054
                     /locus_tag="LLC22_000925"
     CDS             30728..31054
                     /locus_tag="LLC22_000925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434219.1"
                     /translation="MSVDKEAAWRKLMLLIQDENWQEDEAVVAEVQRLGKIANGRIRK
                     KPDKRKQRKGKIVVVLHEGKILMQGTASELSAETGYTRGTIRTYAWRNHTDRKGHEYK
                     YLEEEK"
     gene            31051..31866
                     /locus_tag="LLC22_000926"
     CDS             31051..31866
                     /locus_tag="LLC22_000926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prohibitin family protein"
                     /protein_id="HBK5434220.1"
                     /translation="MNENKLIKLGVAGAVIVGIGVIGGFKFFEKIDNGYVGVRYSMNG
                     GIKDEALTQGVKFVGIDKVIQYPIRLQTIQSKNISVSTSDGKKTTIDIKYDYKVDSTK
                     AAKMYKEFGNITSEDIESGWLKSKLQKVAREVYAKYSLLDVLSGDSSKVEAEVLTNFA
                     KSVESKGFEVEDVTLGVPDVDKETQKSIDAIIRAGQENEKAKLDAETAKTQADSEAYK
                     KTKAAEAEAESNRKVAESVTDNLIRYEEAQARKKHGWVTVNGADTVVTDEAGK"
     gene            32005..32316
                     /locus_tag="LLC22_000927"
     CDS             32005..32316
                     /locus_tag="LLC22_000927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MazG-like family protein"
                     /protein_id="HBK5434221.1"
                     /translation="MDELITKVEQWAKDKGLDQADPKAQFLKVAEEFGEIASAMARSN
                     DELFKDSVGDVIVTLIILSMQKGTNVQECLEMAYNEIKGRTGKMVDGVFVKSSDLEDV
                     K"
     gene            32313..32543
                     /locus_tag="LLC22_000928"
     CDS             32313..32543
                     /locus_tag="LLC22_000928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434222.1"
                     /translation="MKYEIPLSEAGIQAIINGREVNIELPDGTELVIRQSYLKDMAAP
                     VLIDRFNVTDSVVENHLKEFRSSIDDTFRLGS"
     gene            32550..32753
                     /locus_tag="LLC22_000929"
     CDS             32550..32753
                     /locus_tag="LLC22_000929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toxin PIN"
                     /protein_id="HBK5434223.1"
                     /translation="MNNRHRRITKLRKQELNVLKTKFEKEYGISAEETYKVASQFVAD
                     ASDAIRKFGISILNDDRKWEEMR"
     gene            32750..33049
                     /locus_tag="LLC22_000930"
     CDS             32750..33049
                     /locus_tag="LLC22_000930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434224.1"
                     /translation="MKLKDGFYASSHGIGGLMLDMPTKNPKTRKKPKVKVGDMVRCEA
                     EEFIYPFRGYVEHVYNHSAIIRIENTMECDKWLAKSKENLAVARLVDMEVINNEV"
     gene            33039..33203
                     /locus_tag="LLC22_000931"
     CDS             33039..33203
                     /locus_tag="LLC22_000931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434225.1"
                     /translation="MKFKIFEEDTRYKLEKELNDFAKNNEIQHISLATSKRGYANYYA
                     AVVSYVSREV"
     gene            33292..33705
                     /locus_tag="LLC22_000932"
     CDS             33292..33705
                     /locus_tag="LLC22_000932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="autolysin"
                     /protein_id="HBK5434226.1"
                     /translation="MQLLREVDFKQTRCNARDVLKNFRRLERMAGRSLIDIKSPIITD
                     MPKAPKHGNKAEDAIIQMMDIEAERDAILVALMALSLISRQILYYSFCVPDSFSNYRI
                     SREVGYSERSIQRMKSEALIEFAEAYKHGRIIAYK"
     gene            33718..34104
                     /locus_tag="LLC22_000933"
     CDS             33718..34104
                     /locus_tag="LLC22_000933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434227.1"
                     /translation="MWKDYVSLKELKKDLVFKRIVEWSESELILEDGTKMEVVCSESD
                     CCAWAEGEFKNVKLDAVITDIKIFDKGNRLYNGDGHTSYAEVVVYHNRNEIAKAECTA
                     NDGNGGYYYSVCALKVKDKLCIVTDA"
     gene            34655..34879
                     /locus_tag="LLC22_000934"
     CDS             34655..34879
                     /locus_tag="LLC22_000934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434228.1"
                     /translation="MRTYWYVSLNNKYPKPMKGQHRRVVMSVQMKAKYSIVEMIREAT
                     PVEIDYCKLVYCGCGRWKEDHVQKNISKYI"
     gene            34897..35325
                     /locus_tag="LLC22_000935"
     CDS             34897..35325
                     /locus_tag="LLC22_000935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434229.1"
                     /translation="MEKSDTKANRYKPTAAEKKLLEVLINPDNLGKPVQELCSLAKIG
                     RTKYYDAMSKDGFVDLVNETTMDLIKGKASDVLNATYKYALTEKGHQDRKMILTIAGI
                     YADKQELKHSGGVDIRKQYEKMSDEELEELVKRYEKINDS"
     gene            35303..36721
                     /gene="terL"
                     /locus_tag="LLC22_000936"
     CDS             35303..36721
                     /gene="terL"
                     /locus_tag="LLC22_000936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage terminase large subunit"
                     /protein_id="HBK5434230.1"
                     /translation="MKKSTTLNRVEYAVVQRELAIRKARKSFWLFCQLLYPEFYKDDR
                     LYLKDLCHTLQDFYEDKIDKKILVINMPPRHGKTFTARLFVLWMFGQNPKTKIITGSY
                     NQILSSLFAQQTRDGIMVENENVKAEYFKDIFPEVQIKYGDAAKGFWSLDGSEEKNYL
                     ATSPGGTSTGIGANYVIVDDIIKTAEEAYNERVLDSHWEWYNNTLAQRMERPRKQILI
                     MTRWSSNDLAGKMLTRRKNNVHQICYKAVQEDGSMLCNEIMTHDEYLDVVQEMNVDIA
                     EANYQQEPIDQKGRLYQKFLTYDTLPDNIIKIWNYTDTADKGADYFASPVFAETSDHD
                     AYIIDVMYTKEPMETTEIAHANMIIRNRVNKVRIEGNNGGRGFRRNSERITKERGYRG
                     AVFEDFHQSDNKLSRILANSAWVENHVYYPDDWATRWPDFYEAMVSYQREGKNAHDDA
                     PDAVTGIAETIIEADDFEFIAY"
     gene            36733..38268
                     /locus_tag="LLC22_000937"
     CDS             36733..38268
                     /locus_tag="LLC22_000937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010779952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage portal protein"
                     /protein_id="HBK5434231.1"
                     /translation="MFYSGITLKKYKRLRTKYSTQIEEGLFDPNAFMEDMKPFFDDRE
                     RKYLAYTSEKNEIDSREKPKTKIIKVNNKIHAGMYSVVVDQAVNHFTGIPIKWDYDVS
                     EQKRTFIQRMRDKLLGNDISAPSTPEEFETLTRQLSTMRFGMLDPDTATFQGATGLAF
                     RLLEPVETNDGWELRASNIEPWKAEKYENGAVYIKEKYDPYQKKFYEEMKVVTPKSIF
                     TYARYTDYPGTVQGAFKTLGNVPNPLGVINLTEFKNNTNRYCDFEVAEEISDAIDRVL
                     SDQQNEIEQFKLAYMLITGADLSEDKAKKMMEQLGIINLKDPNAKAGYVTKDLQKDFN
                     EYHFDLLKKQFYTVCKAIDFNDEVFKSNSSGEARKWQIISLEAKTNTKEQYFREGLKE
                     CAEVMAAYLDFAEKVTIDPEKIIFTFSRSLPTDLSYLAEALPKLAPYVSKRTIQSQIP
                     FVTDVDYENEMIDVESRQSYPDGEYGGGIVESNRNEVLDQTSRTGRFSKTQNGKSNAK
                     ETK"
     gene            38348..39226
                     /locus_tag="LLC22_000938"
     CDS             38348..39226
                     /locus_tag="LLC22_000938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="minor capsid protein"
                     /protein_id="HBK5434232.1"
                     /translation="MMEFYSTSDQKKYREYVEKNYKSLKMYDAKYKEFIEEYFPSFDY
                     AKVNRLLQMRSDIFRILAESAIDADVNKYFSDRLEDILQRSYVSNANVFAQILNVDLP
                     NYLSKEELERYLNYPWSGKTFSRRLWGNISSLEQKLSNAITTSVASGEGVLVALRTMR
                     EDPEICDMFKREESKYNKAIENLVRTEYAKFAQDGIEKSYIETGVDEYNVLTAKDEKV
                     CSICGGKAKNNPYKLSEAIIGENRAPFHGRCRCTDVPNMPKLGKDIDEEYERLFGDLL
                     DEFAHDSFGINLKRRK"
     gene            39228..39545
                     /locus_tag="LLC22_000939"
     CDS             39228..39545
                     /locus_tag="LLC22_000939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434233.1"
                     /translation="MKDFFEAVLTINVNADIAEAYKTAIESENHPNGLRDHWNGNYAY
                     VVIGDQTVNYQDNTPVDKNTVNLTIQLLSHSLPNLKETVDWYENMGCIVVRTDYKEGK
                     SSN"
     gene            39672..40295
                     /locus_tag="LLC22_000940"
     CDS             39672..40295
                     /locus_tag="LLC22_000940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4355 domain-containing protein"
                     /protein_id="HBK5434234.1"
                     /translation="MIMKHKSLMPMNLQYFAEGDDQKFSFDDFKSFVESNEEAQKFIQ
                     SQSQSVADKQLEAWKQNNLDKIKQDTIKEYEESKKNKSPEQIQLEKLQAEFEAEKALR
                     VTSDNKAFVAEQIAGLELDGELKESISQFMLNNLVSSDTDFTKNAVEGFTSVLNAINE
                     KHADALKELQMKSAFGGTQQSNNQVQQNNETLTNPEEQLGQILQQFN"
     gene            40310..41200
                     /locus_tag="LLC22_000941"
     CDS             40310..41200
                     /locus_tag="LLC22_000941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5309 domain-containing protein"
                     /protein_id="HBK5434235.1"
                     /translation="MKKTSLNNLEYLDISPAINAMQVPNTPFLSYLLGAGKTEPANST
                     EIKWREYDINNDDSSEKLEGGEYPDAESGRTWFNNYTEIFRKSTSVSGTLDAINVNGV
                     GNELTNQVALRGMEMKIDLNRKLITGVKADENGSKGRRMNGILNLINSANKAETATAG
                     AVTRKDIDTLFKLMYEKGYMGEKLCLISPDMQELMTDELDGKSTKIVQFGERVTFGLQ
                     IGNIVSNYGTGIALLEPSLPKGTIAAIDTNYVKLRPLREWRAEELAKTTDSRRIGLVG
                     EYSLEYNASNSGAILNLKSE"
     gene            41223..41438
                     /locus_tag="LLC22_000942"
     CDS             41223..41438
                     /locus_tag="LLC22_000942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311614.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434236.1"
                     /translation="MIGGITVVKKDETKKDEVVKYRVGKTKNFVGFVHPKTRRFITAD
                     SNNEFIISIDDKEAIAILEDAIDVNEI"
     gene            41450..41791
                     /locus_tag="LLC22_000943"
     CDS             41450..41791
                     /locus_tag="LLC22_000943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434237.1"
                     /translation="MDESLKTEIIESTKEDFPDLSEERITNLLEIILLEIESYNTCKN
                     DISWEKLKSVISEVLYKIIKNESEKTVSSVRRGDTTISYASTTNDVSELLLGYGDLIR
                     RVIGCGGLEFF"
     gene            41791..42162
                     /locus_tag="LLC22_000944"
     CDS             41791..42162
                     /locus_tag="LLC22_000944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434238.1"
                     /translation="MNEADILETTYEDSCIIERLTDIEDSNTNITIQDYKKVYDNPIS
                     CALSQGQIDGLAVIEDGEMVNVSTDTYKLFVHPKIKLKKGDRITITQKASGLIFSLFA
                     TKPFYYPSHCEVNLIGSEKNG"
     gene            42155..42550
                     /locus_tag="LLC22_000945"
     CDS             42155..42550
                     /locus_tag="LLC22_000945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HK97 gp10 family phage protein"
                     /protein_id="HBK5434239.1"
                     /translation="MGNLKYESNAEKIIENFKNMTVIAQKEGISFVNDSMNKVVSLAK
                     PLTPVKSGNLRRGYRVVKARKLSSGRIVGAVINNEHYFKYVEEGHRTKNGGFVKGKFM
                     LTRATNLANMSYIPRRFKQMAIKIVKKGK"
     gene            42552..42929
                     /locus_tag="LLC22_000946"
     CDS             42552..42929
                     /locus_tag="LLC22_000946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434240.1"
                     /translation="MKDEIIAAISSKLKEIYPDGTIYLDSVMQSTKDFYFVLSVMESG
                     TENVGIDIQNVSFLIDIALIDNKPNRNLINELVSRCGTFFNTITIDEQILFPKAYLPD
                     EADGVQHIRFTLEFPQYIEWSER"
     gene            42930..43538
                     /locus_tag="LLC22_000947"
     CDS             42930..43538
                     /locus_tag="LLC22_000947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5434241.1"
                     /translation="MGEKRSKTGIISVEKPTWFPLEDETGNFPVYGTALPMGTAVSIK
                     PTANYETTQDYGDSVVQDQFTAFGGAEVELEANGYTHKVLSTITGGKIVKGGALRSGE
                     DIAQDGAFAYRRKKSNGKYRYTVFYKGQFALDSDETSTIEGSKVSFTHPTWKGSFVDV
                     PGLGYMYSVDEDDEGVDKAMIGNWFTKVAIPIEEAELSGGTE"
     gene            43538..43879
                     /locus_tag="LLC22_000948"
     CDS             43538..43879
                     /locus_tag="LLC22_000948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434242.1"
                     /translation="MSKYQTTIKLTKKDEEGKYEQVQFKSAEFLPGTVVEDAAGVMEE
                     MQTATDKQSVKKALSRAYSFIADTLFEGQFTGEDYCKGIDAREIASLTGKLLKSVTAG
                     FDETYTETKKK"
     gene            44121..46910
                     /locus_tag="LLC22_000949"
     CDS             44121..46910
                     /locus_tag="LLC22_000949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tape measure protein"
                     /protein_id="HBK5434243.1"
                     /translation="MILDESGFTAGMNNAVKKLNSFDETIERKSRNGGSSLGSIWKIF
                     AGSFLASGVTRIVGAGFDLIKGSISGAVDRVDTMNNALRNFQNMGFSNSEIMKNIGKN
                     GLLSQGIQGLPTALNDAISHVQLLASSTGDLTRSTQIFKALNDGILGFGGSTDQVNEA
                     VIQLSQSFSNGKVDAQTWNSMINAQLGPTLSAIAKKMGITMGDLKEGLSQGKISVEEF
                     QNQLIEMDTKGGGGLKSLSQIAKDSTKGIKTSIQNAKTAVTRGVGEVIEGLNKALVDS
                     DLGGFKGIIDKVASSMESFLKVIAANIPRAVSFLSNLFDAVQKFGSALKFMMPFLVPA
                     TTAFGALMFQLKGIPTIIKSFNNFKNAIIGVGNSLKIMGAIAAANPFVLIVGAVVGAI
                     AVFGYFMATNEEVRNKVISVWNDVKDSVLGVLKNIKDWGIDTWNSAKEMASNAVESVK
                     DAWSGIKEWFSNTWQGIKNGATGLFDKTVETSMNAVDSVKNAWSNTKQWFSDIWQSIK
                     DSATEKWNEIKGSIMEVAGPLITGLKNAFLHVTFYLETLWNNLVEIGKNVFEILKNVI
                     LTPVLFITSMISGGWEETKNNMIGVWNNIKESALNIWESIKNIFVSYITNIYFAALNI
                     WTGFKLTLINIWNEVVSQAKSIWINVKYFFINLWIDIKYFAIQKWIELKFGIIQTWID
                     LKYNAITTWNNIKQFFKDTWQNIKDIAYNTWISIKNSMINTWNNIKESFWNIVTGIVN
                     SAENAWTNLKNGVSKAINRVKEIFDSLREINLFEIGKNIIDGLINGVVEKWNALKKTI
                     KGIAGSIKDSIKGALGIHSPSRWMRDMVGKNIVQGIIVGIDKEKSKLDQTMTDLVKTP
                     SVQPVITGSNSQPVVQAKQNTSSNAVNEIHLHLNVYGDLPDSMIKQIAKKMKTELTRQ
                     MKRDADAVGGTLYAT"
     gene            46900..47640
                     /locus_tag="LLC22_000950"
     CDS             46900..47640
                     /locus_tag="LLC22_000950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage tail protein"
                     /protein_id="HBK5434244.1"
                     /translation="MQLKRGQFFINQHYSSEFNVYIQNRPASVSASRVIELREREGND
                     SIIIDKAYYKNVTRKIECYYKAPSIDLVQEWEDRITEWLDMNSYSDFILYYDQQYIYQ
                     AIVTEAPEFKGTRKTGNIVPFEFTVSLRPFKENYSGRFAIQQIKAFELFNPEKYASKP
                     LIKLSGSGDASFYINNDKYDLKLLDRELYIDSKLEESYRKLDDNLEHQDHVTLFLDFP
                     FLYPGKNEIKWTNNIHSFEIIPRWWRKV"
     gene            47637..50348
                     /locus_tag="LLC22_000951"
     CDS             47637..50348
                     /locus_tag="LLC22_000951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBK5434245.1"
                     /translation="MIPRIYSPTETDFSTNGLGILKDTTKCEIYEVANGKYELELEYP
                     LGTRFDEYFENDYQIKAKSNDQEEYHIFFIDDKDIDTFLDTVTIYAQSRTNRLGRRAV
                     TFAGVDSKTGREAMAIIENNMDKKSDIRLYSDITTVSSTTFEARNVLNCIAGEQGSLL
                     QYWGGEIKREPFKLSLLKRRGRDNIGTIRYGKDLSGLKVKLDWTGVKTRIIPYADPQS
                     DAGTTSRIYGSPVDSEYINNYPDVYTEHVQFTEEQGVKDVNSLNKIAKNYFKTINPGC
                     DKPKISITVEFDKLTDTEEGKEFAKIRNYGLFDTFKIYHRKYKLYFESKVSGVQYDSL
                     SEKVLKLEAGDAQVAFYQQQAVTIQDKLKDYATNNYMSSFNDYVSSMIAGQGNAGGYV
                     VLWPKEKPSNIFIMDSPDLNKAKEVLRMNKNGIAFSKNGWNGPFNSAWTLDSIFNANF
                     IQTGLIKADIFQNSFNKTGDVLKLVNGLLQIWNNKKKIMELTKKGMEFWNSNSSIGTI
                     GTTDSAGNPFPGASTPTPIEDNSLVIRTNGDGKYILISPKVGKGLVLLGNGKAIYFGD
                     LDVQGKLTVNGKEITGNNSGGSDPGTIPPQLTTEAEKRAWKIWTMLKARGYSEYAAAG
                     ILGNIQGEVGASMNPDTEQLGGPAYGIVQWDGSAYPLVGSPTWNGREYVQRLMNTAGI
                     QEDYRSIEAQVKLLDWCMFNGQWLGKVNPTTVSGFKSINDAKSAAYAFEMNFERPASA
                     HPERQNYAQSWYNKLHGLTSPEPGGNFICPIQKPVTVTSECGWRTSPINGGQEFHNGI
                     DLVNGNPNTPVFAALDGEVVQAGANYYDWYGNYVVIKHNNGKWTGYAHLSRIDVSVGQ
                     KVQKGAQIGLMGTTGPSTGEHLHFQIMKNYWPQPVVDFENPRNYIQF"
     gene            50361..>50590
                     /locus_tag="LLC22_000952"
     CDS             50361..>50590
                     /locus_tag="LLC22_000952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BppU family phage baseplate upper protein"
                     /protein_id="HBK5434246.1"
                     /translation="MSKWNVVLSTTEPYNYVGMIQVRQGNKNTEVMEATIVENGLPYD
                     LSECKVYFESVVGGKYPVQLETKIVDAKKGKI"
BASE COUNT        17442 a         7976 c        10425 g        14747 t
ORIGIN      
        1 ctacactctg agatgtaaga aatatcataa gatatttctt acatcttttt gttttgagca
       61 ggactttaga taattttatt aatatatgct agcatgcttt tgtaagaaaa agaaagaggg
      121 cgtattagtt atgtatctta aaattacgga acaagcacaa gaaagattac aaaaatatat
      181 tgatgaaggc gcaacagtta tattggattt agatgatggc gttggggaat attctaaaat
      241 gggtgtttgc tctttagata ctagttttcg tttacttctt cttgataaag aacagagaaa
      301 aaatgattat aaactccaat tagatagtga tattggggat gtttatataa aagattattc
      361 aaaaatgtac atggatgaac atatgaccct ttctttagat ccacgtctag gtgtatttac
      421 tcttgaaagc ccaagtggtt ctttagacag tcatgttcaa ttagtagatc tacgaccaga
      481 aaaattctct ggaataaaac aataactttc tctctattgt ccataaaact agtctcaatc
      541 aagctgtatt gaaaaaacaa gacaacattc ttaccatggt aaataaaaag acgacacatt
      601 ttgtcgtctt tttttaaatt aactattttc gataaaagat cgcatagctt gtgccattat
      661 ttctggcttt tctctattca attcatgttt tccgttttta ataaagagta gccggccatt
      721 cgttgaaagt ttatataaac gttttgctgc tggtttattc gcatgatctt tggtaccgca
      781 taaaatcaat ttaggaagtc gtgatgtacg aagctgtttt ttgcagtcta atgtttcaag
      841 tgaacgaagt agggtaaggg tttgtttttt agatagacct aatttttcaa atatcttaga
      901 aggtacgcag taaaaataaa tattctggaa agtaagcaat aagcgattag gagactcaaa
      961 ttgtggagcg actaaaacaa ccttttttaa atatggagaa ggagttgcaa gatagtttaa
     1021 agcaataaca gcgcctaaag ataatccaca taaaataaaa ggttccttta tctgattcaa
     1081 ttgtacttcg atgtatttgg ttaagtcgtc taaagtagca gtgtctgtgc tgtttaaatg
     1141 attgaacaat gaaagacttt tgcaagaata actattgggt agataagaga ttacatcttt
     1201 ccatgattgt tcgtcttggc ctagaccatg caaaaaaaca attttcatat tgctctcctt
     1261 tttatagtta tcatatagac tttctttgta ctattaaaat ataaacattc atttcttacg
     1321 tcataaaata aaaaaacagc gcagacacat tgttaaacca acatgttgca ctgtttaagg
     1381 aagccacttg ccgggcttga accggcgacc tcttccttac catggaagcg ctctaccagc
     1441 tgagctaaag cggcattatc attaatacaa ataataggat aacgaatatt aatgtatttg
     1501 tcaacagaat tttttcgaaa aaatgtgttt ctctaatagg aaaacagatt ttagaaaaaa
     1561 taaaaataac aaaaaatgcg aacggtttct ttgataatat aataaaaaaa ttcaaaaaaa
     1621 gtattgcgtt atttagaaga aattgatatt atattcatgt acttgattcc ggcatagctc
     1681 agttggtagt agcgcatgac tgttaatcat gatgtcgtag gttcgagtcc tactgccgga
     1741 gtaaataaag cttatgcaaa gaaaaagaaa tccaatcact tgggtttctt tttcttttat
     1801 tattatgatg aatcaagctt tctgtttttg tcacgtatgt tgtaatcttt acgaaagagt
     1861 agagttggct actcataatc aaccatactt cccatcatcg ctaaatacga aataaatcag
     1921 cattcctaca ccaatcaaag cacaagctgc accaagaaaa gggatgacat tcccaaagtt
     1981 atctgtattc ataagtatgc caccacccac aaacaaaaag ccgccagcaa tcaggttttt
     2041 cattttattc atctcctttc ttacgttata gtatttcctt ctttcaatga gtattttgaa
     2101 agctatctta ttgtatgatg ttcttctagg cctcttcttt attatacagg ccattttcgt
     2161 tatctcatag aaatattcct ttttatctga aaactattgt ataccgtatg acatttttct
     2221 tcatgaagtt gtaagtatat tctcattcaa atgaaaattt catcatagaa gagattgtat
     2281 ttctaaattc ttaagagtaa aatacgaagt ataacttgga tttggaagga tgattggatg
     2341 aaagctatta cgcctgatat gacaacaaaa tttaacaaac agtttcaagc aaatatcaaa
     2401 cagcaggcat tgcagcgggc agttgtgaag aacggaatta ctgcttctgc tgaaaatgtt
     2461 tcagcacatg tggagaatac accggtattt tctatagatt tggctacggg gaaagtggct
     2521 aatcaaatgc aatcggggcg ttgctggatg tttgctgcac tgaacacatt ccgtcataag
     2581 atgctgaatc aattccattt aaaagagttt gaattatcac aaaattacac ttttttctgg
     2641 gataaatatg aaaaggcaaa ttatttctat gaaaacatca ttgcaacagg aaaagaggca
     2701 atcgatagcc ggaaagtagc tttcttactc gctactcctc aacaagatgg cggccaatgg
     2761 gatatgatcg tttcattatt ccaaaaatat ggcgttgtgc ctaaatcggt gatgccggaa
     2821 agtgcgaata gttcaaattc tcgagatttg aataactact tgaacaaatt actgcgtaaa
     2881 gatgcagtag tgttacggaa aatggttgct caaggagaaa cattagacgc tattgaagaa
     2941 aagaaagaag aaatgctaga aagcatttat aacttcttag ctatctcatt aggaacacct
     3001 ccaaaagaat tcgattttga gtaccgcgat gaagaaaaga actatcatct tgaccgagga
     3061 ctgacaccac aaatttttta tgataaatac atcggtgtaa aattagatga ttatgttagc
     3121 gtgatcaatg caccaacaaa agacaaacca ttcaatcgtt cttatacagt agagatgcta
     3181 ggaaatgtcg ttggcgggaa agaagtcaaa tatctgaatg ttgatatgga aactttcaaa
     3241 aaattagcga ttgctcagct tgaagaagga gaatctgttt ggtttggttg tgatgtaggt
     3301 caatcttcta ctagaactag tggcatcatg gccttagatg cttattcaat ggatgatcta
     3361 tttgatacgg attttacaat gactaaagct gaacgtttag attttggaga aagtctgatg
     3421 acccatgcga tggtattgac cggtgttgac ttagtagacg ggcaatcaac aaaatggaaa
     3481 gtcgaaaata gctggggcga aaaagttgga aagaatggct tctttgttat gagtgatgcc
     3541 tggatggacg aatatacgta ccaaatcgtt gtaagaaaag atttattgac gaaagagcaa
     3601 ttaaatgcgt tcaatgaaga accaattgtt ctatctccgt gggatccaat gggtgcttta
     3661 gcatagacga gtatttcaat gaagagtatg tagtaaagat aaaaagagct ggcttaagcc
     3721 agctcttttt atctttaaag tccattccct gttttttatg gtccctgtgc tataattcta
     3781 aataaaggat aaggattgga aataatcctt ttatcattaa aaatatgatg acgaagtaga
     3841 ataaaattgg gagtaggggg gaaagtcatg gatatccaaa ctgttttatc tgatctgaaa
     3901 ttaaatggta aagtgattcc agttgttggt ggcgatgtta atcagaccta tcgtataaaa
     3961 accgaacatc gtgcttattt tttaaaaatc catccgaatg taaaaaaagg attttttgaa
     4021 gcagaagtag acggattaaa agaactgtca gcattcgtac gtgtaccgga tacgtatatg
     4081 ctaggtgaaa caagtgaagg cgcttatttg ttaatggaat ggatcgagcc gggaaaaggg
     4141 gatcaacgag atcttgctgc agctttagct aatctccatc agcaaacagc gccacaattt
     4201 ggttttcgta aagataacta tttgggtaca cttgttcaga aaaattcttt tgaagaagat
     4261 tggtggactt ttttctttaa agatcggctt gaatcccaga tttctttggc agaagaaacg
     4321 aatcgatgga atgtacagcg tcaagaaaag tatctgcgat ttaaagaacg tgtattgaaa
     4381 tcggttgaac caaaaaagat cactccacgc ctcttgcacg gagacctgtg gagtggtaat
     4441 gtgttctttg accagcaagg gcatccagtt tttgtcgacc cagctgtttc ttatgggaat
     4501 cgggaacaag atattgcaat gagccagtta ttcggtggtt tccgaccgga atttttagat
     4561 gcttatcaaa ctatatttcc attagaaaag ggatggaaag accgactgcc gatttaccag
     4621 ttatattatc ttttggcaca tttgaatatg tttggagaaa gttacggttc ccaagtagat
     4681 caattactag aaaattttta agaggagggc gtgtttttgg caaaaaaata taccaaaaag
     4741 catgaagttt catattatga gtgtgacatc aaccaaacga tgacatttcc ttcgatgtta
     4801 ggagtagtta tcaaaacgtc tgaagatcaa agcgaccagt tgggaagagg cagtgaattc
     4861 gtcaatagct ttggacttac ttgggtcatc acgaattatt ccatggagat taatcgtctc
     4921 cctagagtcg gtgaagtaat ctcagtaacg actcaagcca tggagtacaa taagtttttc
     4981 tgttatcgga acttctggat ccatgatgaa gatgggaaag aattagtcaa aatagaatct
     5041 gttttcgtat tgatggattt tgtgaatcga aaaatgagca gtgttaatga agagatcatt
     5101 gctccttttg agagtgagaa gatcaagaaa atcaagcgtc aggaaaaaat tgaaaagatt
     5161 gattcgggct tcatgttgcc atatcgtgtt cgtttttatg atatcgatag taatcagcat
     5221 gttaataatg cgatgtattt taattggatc attgacgtat taggatatga ctttttgact
     5281 acgcatgttc cagaaaaagt aattattcga tttgataaag aagtagagta cgggaatgag
     5341 atcgaaagcc attttgaaca aatccctatc gaaaatggtg tcaaaacaaa acatgaaatc
     5401 cgaatgcaag aacagctgta ttgtgaagca aatattatat ggaaaaataa ataaaaaaga
     5461 ggttgtgaca gaagggggca acttcaagaa ataagaagaa atttacgaaa attgtttctc
     5521 aaatttttgt aaattttcga cttagttttc gaagaagcta tttttgtcac agcctctctt
     5581 tttaagttta gctattagat aatgatgttt agttttggat aaacgaaatc aattcttcac
     5641 ccgacaaacc atagtttaca gcaatcaata gttttaaacg tgctttttga ctattaatac
     5701 tgttacagaa aataatcccc attttttcta gttcttttcc cccgccttca taatcataaa
     5761 caggctctgc gattccattg aaacaacgag aaacaagtac tacagggatt ttttggacaa
     5821 gaagcttttc caaagcagct aaggcttgtg gagggagatt ccccgcacct aaagcttcga
     5881 ttaccaaacc gtctactttc gtatgggcga tggcttccaa taagtcccct tgcatcccag
     5941 catatgcttt aacgatcggg atagtcccat ctacagcgga aatgtccagt cgctttgttt
     6001 ctaaaagttc ctgcaagaat aaaattcgat tcttagttac taagccgatg ggacccaatg
     6061 taggtgttcg gaaagtagca acatttgtgg tatgggtctt tgtcacgtag cgtgcagaat
     6121 ggatctcatc gttcatgacc accaaaaccc ccttatctag cgcttcttca caacttgcga
     6181 cacgaatcgc actttcaaaa ttataaaggc cgtcacttcc aagttcatta cttgaacgca
     6241 ttgccccagt caaaacaatt ggtaatttgt tgccaatcgt tgtatcaaga aaaaaagcag
     6301 tttcttctaa tgtatctgta ccgtgtgtga tcaccactcc ggatatacct gatgcataag
     6361 cggacaagat acgttctttt aataccaaca tgtgagaagg catgatgtgt ggtgagggaa
     6421 gattgaagat atcttcaact aataattcta catgcttggg gattgtgatt tctgcatcta
     6481 ataatgggtt tgccacatca ggactaacac cgcccgtgag catgttttct ttcatggcga
     6541 tcgttccgcc ggtgtgtagt acaagtattt ttttcatttt acagacttcc ttacgaataa
     6601 ttttgcatag ccgttaaatc ttattgtata ctatataaaa gagttttgct atcagtgaag
     6661 aataacgaat agcctaactt atcataaaaa agctgacctt attaaaatgg aaaagactca
     6721 accttgacct cctaatacaa tggagtatct ggttgagttt cttttacaag aaagcagcca
     6781 aggaaatcaa tcacgaaggt ggccggaaat gatcagaatc ggattaacat cgtttaaaga
     6841 acatgacaaa ttaactggta aaaagaataa cactctttat gaatatgcag ggtttctacc
     6901 cttagtggaa ttagatactg cctattatgg aattccccga aagtcctcag ttgagaattg
     6961 gataagtgaa gtacctgaat catttcgctt tgtagtcaaa gtctatcaag gaatcagcgg
     7021 tcaaggagac tggaagcctt attatcagac cgaagaagag atgattgcgc attttttaga
     7081 tgttatgtcg ccaatggtag atgctggaaa gatgttttgc tttttagtcc aattcccctc
     7141 atcattcaaa tgtacgaaag aaaatgtcca gtacttgcgc aaacttagaa agtggtttga
     7201 gggttatcct gtttctatag aattgcggga ttattcttgg tacagcgatg aatttcttga
     7261 acgtacaaga aactttatgt ctagagccgc tttttcttta gccatcatcg atgagccaca
     7321 gttgctgaat acaacgattc cttttgatcc atttgtcacc aatccgaact ttgctctttt
     7381 tcgattccat ggtaggaatg cgcaaggatg gcaagcaaat gataaagagt ggcgtaaaaa
     7441 aagaacgtta tatcgttatt cagaaaaaga actgcaagaa ctagcacatg aagtcaaagt
     7501 agttgattct aagacaaaag aggtaggtgt gatttttaat aataattctg gtggtgatgc
     7561 ggctgaaaat gcattagcac tgcaaaaaat attaaatatc aagccagatg gactcaatcc
     7621 aacccaaatg gatctgtttt aagggcttat tttattcaag aaaggggcga agtctatgat
     7681 caaagctatt ttttttgata ttgacggaac attggtcacc aatcgttcaa aagcgttgga
     7741 atcaacaaaa caagcaattg aatatgctcg gaaaaacggc attttatgcg gtgtagcaac
     7801 ggggcgcagc ccagtaaaga tcaaagaaat cattgatgaa ttggaattag atatgtatgt
     7861 cgtgtataat ggtcaactgg tttttactgc agatcgcacg attatcgacc acccttttga
     7921 acaaaaagta ttggaacata ttgttgaatt tgcagatgag aaccatcgac aaatcgtttt
     7981 tggtgcgaga aatcggttag atggatcaac gacgatgcta ttaggacaat cgatttttat
     8041 caagcgacta gtcagctttt taccgcgtaa attcccggta cgtctgatga aaaaaatcct
     8101 ccaggttttt agccctcacc gacaaaagga tcgttatgaa acgttagaga tattaaaaga
     8161 accaatttat caatgtatat tgctcagtcc ggagtcagaa cagaaaaagt tagaacatcg
     8221 ctttcccgag tgtacgtttc agcgttcaaa tacgtatact gtagatatca tcccaaaagg
     8281 tggttcaaaa ttactaggca tccaagcttt cgcaaatgct gtcgaaattg aaatggaaga
     8341 aattatggca ttcggcgatc attacaatga tatcgagatg ctgaaaggtg taggaattgg
     8401 agtggccatg gggaatgctc agatcgaagt aaaacatgct gcagactttg tgactcaatc
     8461 aaatgaagaa gatgggatat acgaaggact gaaacacttc ggtctgattt attagtcaat
     8521 gaaagaagga aaaaatcagt atggaagcag agacaccttt tcaaaaagta gaaacattcc
     8581 acaaaacttt tgatccaaga agaccagaga tacccacggc ttttacagaa aatgaagctc
     8641 atacacgtgc tgcgttcaaa atagaagaac ttgttgaatt tgttgcagct acttcaccta
     8701 ataaagaaca actgcatgaa gctgttatgc tgctgcacga agcattagat aaagcagaag
     8761 aaaaaatact tggtaaaaca cagtggggaa gtgatccgct ggttgaacaa gtagatgcac
     8821 tgacagatat cctttacttt acttatggtt ctttttcatt actaggaata gtgcctgatc
     8881 gaatattcga aatcgtccat caggcaaata tggggaaatt atttccagat ggaaaacctc
     8941 attatgaccc tgtaacaaat aaagtgttga aacctgaaaa ctggcagatg gaatatgctc
     9001 cagaacctaa aatcgcggca gaaatccaac gtcagattca agaagcgatt gctaagaaga
     9061 aatccgctga tataggcatg tgcacaaatg aaaaagagtg atcagagttt cactattttt
     9121 gttatcttta tacgatggaa aaacaaaaga ttttcgttta agttagtgaa tgcatgaaaa
     9181 tagtatgcta taatctagaa tagatgtctt ttgcacgaga gacgtattat ttggatttat
     9241 gccaagcaga acgccatctg ttgcataaaa gatgcatact gaaaacggag gaaccataaa
     9301 tgggaaataa tgttatcatc ggaatcgtca ttgcaatcat tatagtcgcc attgtcgtct
     9361 ttttggttag ttacttgatg aagaaaaaaa accaagatcg attggatgcc ttagaaaaac
     9421 gcaaggaaga attatttgac ttgccagtga ttgaagaagt cgatgatgtt aaaaaaatgc
     9481 atctggttgg gcaaagccaa aatacctttc gtgaatggag tcaaaaatgg aatgacatat
     9541 ctacttcctc gttcgctgaa ctagaaagtc aaattttcga agtggaaaac ctcaatgaaa
     9601 gttttcggtt cttaaaagga aaaaaagcag ttgttgaagc agaagctaca atggaccaaa
     9661 tggagaaaca agtgacggaa atccgtgaag gtctaaagga attgcgggaa acggaagaac
     9721 gcaactcact agctgttcag caggcacttg acgtctatga agaactgaaa gaaaaagtca
     9781 gagaagacga gcatgaatac ggaccagctc tttttgaatt gcaaaaacag atcaaagtga
     9841 tcgaaaaaga atttacgcag tttgtgactt taaacacttc tggagaccct gttgaagccc
     9901 gcgaggtttt ggataaagca gaaaaacata cgtatgaagt ggaagctctg atgaaaaaaa
     9961 ttccaccgct gtatgaggag ctccatacca ctttccctga acaacttgaa gaaatcagtg
    10021 atacttacga gaaattgatg gaagaacaat atgtattccc agaagaagat cttgctgaag
    10081 atatcgcaaa agtaagtcga agaattgaaa attcattagc caatcttgaa aaaacagaag
    10141 ttgaaacggt cgaatttgaa aaccgtgaaa cagctgattt gattgattcg ttatatgata
    10201 tcttagaacg ggaaatggaa gctcagagat atgtaaaaac taaccaatca acgattgcag
    10261 agtatatcaa acatacaaca aagaataacc gtcaattatt gattgagctg gatcacacat
    10321 ctcaaagcta tacattgaac cacaatgaaa ttggccgtgt acgaggtttc caaaccgaag
    10381 tggaagaaat ggaacgtcaa aatgaacaga tgattccaca gatccgtcaa cacgaaattc
    10441 cttattcaga agtgcgcacg ttctataaaa cagtcttcaa agtcttagaa gatatcgaaa
    10501 agcaacaagt agagatcgac gactcattac atgaattgag aaaaggcgaa aaagaagcgc
    10561 aagaaaagat cgatacattc gaattcaaat tgcgcagttt gaaacgtttt gtagaaaaac
    10621 aacgtttgcc tggcttgccg aatgattacc tagaattctt ttttgttgct actgaccgta
    10681 ttgaagaact aagtgttgtc ttgaataaaa ttcgagtaaa catggaagag gtcaatcgtt
    10741 tagttgctct atgtgaagaa gatctagaat tattagataa gaagacacat gatttagtag
    10801 atgcagcagc attaacggag caaatgctcc aatatgcaaa tcgttatcgt catacacacg
    10861 aagaagtgag agaagcaatt gataaaagct actatttatt caataaagaa tatcactatc
    10921 aagaagcatt agacgaaatc ggtacagcat tagagcgagt agaacctggt gctttcaaac
    10981 gcatcgaaga tttttatttt aatcatccag acttagtata aagcaaaaaa gttagtaaac
    11041 cagcaagagc aagacggatt attgtcttgt tcttgtcttt ttttgtatat ttgaaaattg
    11101 aaacaagtga aaatttcacc tgctcttgaa agcaccttgg acaaccgtta taatagaaaa
    11161 gaatttcaaa aaagaggggt ttcttatgat atattttgat aacagtgcaa caaccccaat
    11221 ctttccgcaa agcttagatg catatgtaaa aaccagtcag cggattattg ggaatccatc
    11281 aagcttgcat gatttaggca atcaagctaa ccggttgttg cagcaagcaa gaaagcagat
    11341 cgctgatttg atccatgtag aaccagaaga aatctatttt acttcaggcg gaacagaagg
    11401 agataactgg gtattaaaag gaacgatgat cgaaaaaaga gaatatggga atcatatgat
    11461 catttcagga gtcgaacatc cggccgtcag cgagacagca gaacaattaa aagaattagg
    11521 aatcgaagta agtatcgccc cagtggataa acgcggattt gtacgtgtcg acgaattgaa
    11581 agaattaata agaaaagaga cagtattagt ctctgttatg gctgtgaata atgaagtagg
    11641 atcgattcag cccatccagg aaatcagtga tcttttggat gattttccta aaattcattt
    11701 ccatgtagat gctgttcagg cgattggaaa agtaccattc tcgcaatggt tgacagaaag
    11761 agttgatttt gcaacatttt cagctcataa attccatggc ccacggggaa ctggtttcat
    11821 ttattggaaa aagggtcgtc gtttagcacc attactgaca ggtggagggc aagaaagaaa
    11881 tcagcgaagt gggacagaaa atgttccagg tattgtggct atggttaaag ctttacgttt
    11941 atcattagag ataaaggaac aaaaacctga gcagacacaa cgcttaaaag tagctctaat
    12001 caatgcgttg aagacgtatg agaaagtgac gattttttca gaaggaactg actatgcacc
    12061 gcatatttta tgttttgctc taaaaggaat tcgcggcgaa gttctcgtcc atgccttaga
    12121 agaaaaacaa atatttgttt ctactactag tgcctgctcc tcacgtaaac atatggcaag
    12181 cagtacattg cacgcaatgc atgtaccaaa tgatctggct acatctgctg ttcgaatcag
    12241 cttagatgaa aacaattcgc ttgcagaagt cgagcaattt atgattattt tcaagcagct
    12301 ttataagaaa ttttctgcaa tcaattaaaa gaggagtgtt cttgtgaaat acagtgaaat
    12361 tatggtccgt tatggggaac tttcgacaaa aggaaagaat cgaaaaagct ttatcatgca
    12421 actagcacaa aatgtcagac aagctttgaa agactttcca gaaatcaaaa tccatgctga
    12481 tcgggaccgg atgcatcttt tattgaatgg cgcagacggg cagctagtta ttccaaaact
    12541 agcaaaaata tttgggatcc aaaatttctc tccaagtatt cgtgtagaaa aagatgtcga
    12601 agttttgaaa caagctgttc aagacatcat gaaagaaatt tatactggga aagaaacatt
    12661 taaaattatc gctaaaagaa gcgatcacca atttgaattg acaagtaatg aattgaatca
    12721 aacattaggt aatgctgttt ttgatatttt cccgcatatc caagttcaaa tgcgtcaacc
    12781 agatattcca ttacgtgtag agattcggcg tgatggcgct tatctatcgt atgaaacgat
    12841 caagggagct ggaggattgc ccgtaggaac aagcggaaaa ggaatgctta tgctttctgg
    12901 ggggattgat tctcctgtag cagggtactt tgccatgaag cggggagtgg aaattgaagc
    12961 tgttcatttt gctagtccgc cgtatacaag tgaacaagca ctgcaaaaag caaaagatct
    13021 aacagccaaa ctagcacctt atgtgggaac gatccatttt atcgaagtgc catttaccga
    13081 gattcaagaa gaaatcaaaa agtcagtgcc acaaggatat tggatgacaa ttactcgtcg
    13141 aatgatgttg cgtttgaccg atgaaattcg ccgtattcgt catggtttag tcattttgaa
    13201 tggtgaatca ttaggtcaag tggcttcaca aactttgcaa agtatggtgg ctatcaatga
    13261 agtaacgaat acgccaatca ttcggcctgt agcgacaatg gataaacttg aaattattga
    13321 agtagcagaa cagatcgata catttaatct ttctatccag ccttttgaag attgctgtac
    13381 gatttttgct cctccacagc caaaaacacg ccctcaactg gaaaaggtcc atcaatatga
    13441 agagcgttta gcaatagatg aaatgatcca acgagcacta gctggcttga agatggaaga
    13501 gatacaagca gaatcgtcta atgaaaaaac tgaagaattt tcagaattgc tataagaggt
    13561 tatgaaaata gtgttttgac cagagtatta gagaaacaaa acgaaaaaat agctccatgt
    13621 attttaccgt ttttgaacta atgtcgaaga ttagctgatt gaataccatt tatcaagaag
    13681 ttatggaaaa gccggttctt ttttactaac tgaaaaataa aattttattt agagatcaag
    13741 ctacagttga taaatgatat aaaaaagaga atttcccatg aaatagcgag gttgtgacag
    13801 aagtgggcag cttcaagaaa taagaaggaa tttacgaaaa ttgcttttca aatttttgtg
    13861 aaatttcggc ttatttttcg aagaagttac ttctggaaca ccgtgtatca gaggttgcga
    13921 aaaagctgcc ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatatttta
    13981 cgtttggttg agcttattac cgcagatgca agcttttgaa caccgtttta tttgtctcac
    14041 acccttttcc ttcctacttg taaccttgct cccgtgttag aaacatgtta cactaaatat
    14101 gtgaaattat taacaaggag cgtcgttatg cgagaaaaaa cagatacact gccaaaagca
    14161 actgcgaaaa gattaccttt atatttacgc tacttgaaga tgctggatga ctcaggtata
    14221 agtagaatca aatcaaatga gttcagcgaa atcacccaaa ttccttctgc aacgatccgc
    14281 agagacttct cgcaattagg cgagctaggc agaagcggat atggctatga tgtccctttt
    14341 cttatcgatg tattcaataa tatccttaat actaaagaag aaaaacgaat cgcattagta
    14401 ggatatggaa atcttggcaa agcattgaaa cacaacaatt ttagaagaaa tgaaaatcta
    14461 aatatcgtgt gcgtctttga taatgatcca gcactgatca atcgagtaat tgatggagaa
    14521 atgatctatc cgattgatcg tttcgcggag atagccaaag caaaaaatgt gacagtagca
    14581 atctctacgg taccaagtaa atattcacaa tctgctattg atgaaattgt caaaggaaat
    14641 gtaaccgcta tacttaattt tgcgcctgac agagtaactg tcccagctta tgtcaatgtt
    14701 caatacattg atttgacaac cgagttgcag acgcttattt actttgatga gaattactca
    14761 gaagtttttt cttaggaaaa tttgagtagg cttattgatc ttgcgagaac tcgtcgtaat
    14821 tctttcaaaa attttttagt actaaatgaa gtggtttttt cacgaccact tgttgactaa
    14881 aaaaaaaaac cattgtagaa tgaagcataa cgctgaacaa gaggagtaac tggcacattc
    14941 attcttagag agagaactat ctgctgaaag gttctcaatg acaaccagtg aaggtagctt
    15001 gggagtttct gtcttgaatg gagtagagat agacgagtcg tgatcgttaa ctcacttgag
    15061 aggcaataat gattgattat tgcaatttag gtggtaccgc gtaaatcata cgtcctagaa
    15121 tacgaaagta ttttaggacg ttttttagtt taaaggagga aaacagcatg acggaagaaa
    15181 ataacctatc aacaaaatat aatccgcaag aagttgaagc tggacgttat cagcattggt
    15241 tagaacaaga tttgtttaaa ccgagcggag ataaaaaagc aaaaccttat tcaatcgtaa
    15301 tcccgccccc aaatgttact ggaaaacttc atttagggca tgcttgggat acgaccttgc
    15361 aagatatgct gattcgtcaa aagagaatgc aaggatatga tactttatgg ctgcctggta
    15421 tggaccatgc aggaatcgcg acacaagcaa aagtagaagc gaagcttaga gagcaaggga
    15481 tttctcgtta tgatctaggt cgtgaaaagt tcatcgatca agtgtgggaa tggaaagaag
    15541 agtatgcgag ccacatccgc gaacagtggg ctaaaatggg cttatcttta gattacagta
    15601 gggaacgttt tacattagat gatggattat ctgaagcagt acgtaaagtt tttgttacct
    15661 tatacgaaaa aggtttgatt tatcgtggtg aatatatcat caactgggat cctcaagcac
    15721 gaacagctct atctgatatc gaagttattc ataaagatat cgaaggcgcc ttttatcata
    15781 tgagctatga actagcagat ggatcaggcg tagtagaaat tgcgacaacc cgtccagaaa
    15841 cgatgttggg agatacggcg attgctgttc atccagaaga cgagcgttat caagcgctca
    15901 tcggcaaaaa agtgattcta cctttagtca ataaacaaat cccaatcatt gcagatgaat
    15961 atgtagatat ggaattcggg acaggtgtag taaaaatcac tccagcacat gatccaaacg
    16021 actttgaggt aggtaatcgt catgatcttc cacgcgtaaa tgttatggat gatgatggta
    16081 cgatgaatga actagcagga aaatatgctg gaatggaacg ttttgctgct cgtaaagcaa
    16141 tcgtgcaaga tctgaaagaa atcggtcgat tgattaaaat cgatacgatg atccacagtg
    16201 tgggtcattc cgagcggaca ggtgtcgttg ttgaacctcg gctgtctact caatggtttg
    16261 taaaaatggc gccgttagcg aaaaaagcca ttgataacca agaaacagat caagcagtgg
    16321 aattcttccc tccaagattc aatcaaacgt ttttacgttg gatggaaaat gtccatgatt
    16381 gggtaatctc acgacaatta tggtggggac atcaaattcc tgcatggtat cacaaagaaa
    16441 caggtgaaat gtatgtaggg atggaagcac cagcggatag tgaaaactgg gtacaagatc
    16501 ctgatgtttt agacacttgg tttagttcag ctttgtggcc tttctcaaca atgggctggc
    16561 cagatacgga aagcgaagat tataagcgat acttccctac tagcacttta gtaaccggtt
    16621 atgacatcat tttcttctgg gtaagcagaa tgattttcca aagcttggaa tttactggcg
    16681 aacgtccatt tgagaatgtc ttgattcatg gattgattcg tgacgaacaa gggcggaaga
    16741 tgagtaaatc attaggtaat ggaatcgatc cgatggaagt aatcgaaaag tatggagcag
    16801 atgctctccg ctggttctta tcgaatggtt ctgcaccagg acaagatgtc cgcttcagct
    16861 atgaaaaaat ggatgcttct tggaacttta tcaacaaaat ctggaatgct tcacgtttcg
    16921 ttatcatgaa tatcgaagga atgaccgtag aagagatcga tttatctgga gaaaaatcag
    16981 tggctgaccg gtggatcctt actcgtttga atgaaacgat cgaacgagta actgagctat
    17041 ttgatcgttt tgaatttggt gaagcaggtc gacaactgta taactttatc tgggatgatt
    17101 tttgtgactg gtacatcgaa atgagtaaag aagtacttta tggagatgat gctgtttcaa
    17161 aacaaaccac ccgtagcatc ttagtccata cacttgatca gatcctacgt ttattgcatc
    17221 caatcatgcc attcgttaca gaagaaatat gggaacatat tcctcatcag ggaaattctc
    17281 tagtagtggc agaatatcct gttgtacgtc cagagtttga tgatgaaaca gcttctaaag
    17341 ggatggaagt attgaaagaa ttgattcgag ccgttcgaaa tattcgttca gaagtgaata
    17401 caccattgtc taaaccaatt acgttgctaa ttaaaacaaa cgatgctaaa atcgatcaat
    17461 ttttagttga aaatacaagc tatatcgaac gcttctgtaa tcccgaagag ttgacgatat
    17521 caagtgagat cactgcgcca gatctagcga tgtcagctgt tctgacaggt gcagaaatct
    17581 tcttgccgtt agcaggattg atcaatattg aagaagaaat caaacgatta gaaaaagaac
    17641 tggaaaagtg gacaagcgaa gtaaaacgtg tccaaggaaa actttctaat gaacgttttg
    17701 tttctaacgc gccggaagaa gtagtagagg cagagcgtgc aaaagaaaaa gattatttag
    17761 agaagcaaac ggctgtcaaa gaacgaatcg aaagtttgcg tactattcaa taagaataga
    17821 aaaagagagt gtgaaatcag ctagctatta ctaaaagcta gctgattgaa catcgttaca
    17881 ggaaagagtt tgagcctcac tcttagcttc gattcataag gagatgtgac ataaattttg
    17941 tcgcatctct tttttagtct actcttatta tgtaggagaa ggagggaggt ggatcatgta
    18001 tcaagagtca ataaagtagt tgataaaatc gttcctctct ctgtttcttt tctctttgtc
    18061 atacttttat ttttcttatg tgttctattt gttataataa aagagaaatg ggggaattgt
    18121 tgatgacgat tgaagaagca atagaatgga tccatagtcg attaccattt ggttcacgtc
    18181 ctggccttga ccgagtcgaa gctttattag aagtggtagg gcatccagag agaaaagtaa
    18241 aaacgatcca tatcgctgga acaaacggaa aaggttctac tgtagcttat ttgagaagcc
    18301 tattagaaga ggctgggctg acagtaggta catttacttc accttatatc gaaacgttca
    18361 atgaacggat cgcaatcaat ggcaaaagca ttccagacaa tgatttgatc cagcttgtaa
    18421 aaaaatatca gccactgatc aaacaacttg atcaatttga agcagtagct ggtattactg
    18481 aattcgagac attaacagca atggcatttg attatttttt gatgaagaaa gtggacgtag
    18541 cgattatcga agttggctta ggcggcttat tggattctac caatgtagct gtaccaatgc
    18601 tgacgggaat aacaacgatt ggacttgatc ataccgaaat acttggagat acaattgaag
    18661 aaatcgctgc acaaaaagct ggaatcatca aacaaggcgt tccagtagta acaggaaata
    18721 ttgccccaga agcttttact gtcatccaac aaacagctaa agcaaaaaat gcaccgcttt
    18781 atgtatacgg ggaaaattat aaaataaact atctgcatcc tgatgagatg tggggagaag
    18841 tatttgaatt ttttaatgaa ataggaaaga tccctcaatt aaccactccg cttttagggc
    18901 aacatcaagc tgaaaatgca ggagtagcca tcgaattgta ttttgtttac tgtcaattgg
    18961 aaaagctgcc tttccgagaa aaagatgttt tgaagggatt gaagaaatct cgatggccag
    19021 gaagaatgga gcgtttgagt aacgagccat tagttgtttt agatggtgcc cataatacgc
    19081 atgcaatgaa ccggcttgtt gagaatttga aaaaagaatt caaaggatat caaatcaaca
    19141 ttttgttttc cgccttacga actaaaaatg ttagagaaat gctagaacga ttgcagcaag
    19201 taccaaatgt ccatatttat ttgacgacct ttgaacatcc aaaagccatc gaattaagtg
    19261 aagtatcaga tttagcaagt gagagagtat caatcgtttc attgtggcaa ttcggattag
    19321 cagatatatt ggaaaagatg acaaatgaag acgtattagt tgtgaccggt tcactttatt
    19381 tcatttcaga agttcgccat ttattaatac aattaggagg agatcatgaa gtataatgca
    19441 gtgatttttg acatggatgg tttgctgttc gacacagagt tagtgtatta cgaagccaca
    19501 caagtagtag cagacaagat gggttttcct tatgataaag acctgtattt aaaattctta
    19561 ggtgtttcag atgaagaagt atgggcgaat tatcatatga ttttctcgga atttggcaaa
    19621 acaagtgtac aaagattcat agatgattca taccaggaaa cgcttgaacg tttttcgcaa
    19681 ggagcggtac aaatgaagcc cggtgtgttg gaactcctct cttttttaga agaacatcag
    19741 attcccaaag ttgtcgcttc cagtaaccaa cgagcagtca ttgaactttt attgaagaag
    19801 aacaatctgt ttgaacgatt tgagacgatt gtttctgcag aaaatgttca acgagcaaaa
    19861 ccagacccag aaattttctt gttagctaat cagaagctag gtacagcgaa gaaagaaaca
    19921 ttgattttag aagattcaca aaatggtatt ttagcagctt ctgcggctga gatcccggta
    19981 gtcatggtac cagatctgct tccaccatcc caagaattga tcaaaaaaac agctggggtt
    20041 gtttcttctt tacatgaaat ccctgcattg ttaaaataaa aatccatctc ttttcgtatc
    20101 ttattttaga taagatagaa aggagatgtt tttttgggaa aacgattgat caaagaagta
    20161 cctactagct ctttaccaag ggaacgtatg gaaatttatg gcgcggaagc tttatcggat
    20221 caggagcttt tggcaatctt actgcgtacc ggtcaacacc cttatagtgt gatgtcgatt
    20281 gctggaaatc tgttaaaaac gtttggagga ctggcctctt tacgacaggc tactttgcat
    20341 gagttagaag agattcgagg gataggacgc gtgaaagcaa tcgaaatcaa agccttgatc
    20401 gaattaggtc gacgaattca gacggatcat gaaagagcgg ctccaccggt tcgtaccagc
    20461 tacgaattgg cccagcaatt gattctggaa atgaaagatc acaaacaaga acatttggtt
    20521 tgtatttatt tggacacgaa gaatcaagtg atcttaaaaa aaacagtgtt catcggttcg
    20581 ctgaatcagt cagtcgctca tcctagagaa attttccatt atgctgtacg ttattgtgca
    20641 gcaaggatcg ttttagcgca taatcatcct tccggaatat ataagttagt acacataaat
    20701 tatataagga aatttactgt tatattgcca tctggaaata ctattatgtt atcgataatt
    20761 gaacgccata atgcattttt ttcttcttcc gaagattctt tataaatttc atcgaattct
    20821 tttgatagaa taaattcgac attttttata tctattttag ctggctctac ttcaatttca
    20881 tttaattctt tcattaaagc ttctcgatct tttttgtatt cctctaagtc tataacttca
    20941 ttcaagtagg ctttcttcaa tctatctaat ttattctcaa tatttttctt actatttttc
    21001 tttttaataa tctttggttg tttttttgaa tagtttattt gtatttgttc aaatttttgt
    21061 ttagtagctt caaaaatata acgttctaaa tttttttcgt aaaaagcgcg cttatttgtg
    21121 caacgtaatt tattatttct tcgttttaca catctataac aagtcctttc gtatatagat
    21181 tctgtaccgt cttttttctt atatcttgct ttaatagttt gaccagctac tgatccctga
    21241 cagtcagaac attttaataa acctttaaaa atgtaatcac gttttgcatt tgtttttaaa
    21301 tttttaggta aggctttttg aacagcataa aaaagttttt tatcaataat aggaggacag
    21361 taatttttat tatttcttaa ttcaccaatg tattttttgt tcgtcaacat atttttaaca
    21421 ctttgataat ctctaacgat tccatactga gagcctaaat aataaacagt ttttcttaaa
    21481 ctaccactag aaagaaagta gttgaatata tctatcacga taggagcatc atcatttatt
    21541 actaatttct tattttctat agagtagcct aacggagttt tcccgcttac tacttcacct
    21601 tgtgcaattt tatttgccat aacagctttg atgcgttctg aatcaatttg ggcttccaat
    21661 tcagcaaaac tcattacttg tgcaatgaaa gttctgccat acgctgtagt tgtatcataa
    21721 tattgttgag aaacagcatt ccaagaaaca ttgtgttttt ctaaaatttc ttgagtgttt
    21781 aaataatgtc gtagatttct aaaccatcta tctaattttg taaataaaat tagatctatt
    21841 ttattttctt ttacatcttg taatagtttt tgaaattcat cacgatttat tttttgacca
    21901 gaaataccac cgtctacata ttcattaact actttcaaat ccttgtgttg ttcgatatat
    21961 tcatagaggg tttctttttg ttctctaaga ctatctccat gtttggcttg ttgttcagtt
    22021 gatactctca tatataatgc tactcgtttc atgttatctc ctttcgaatg tatgttctta
    22081 tcgttgtaaa agaaaagccc gaaggctaat ctttttacta cacatctgtt aattctaatg
    22141 atcttctgta ttgttcagct tgagctagtt tagtaaaaga tacagttccg ttataatttt
    22201 ctaaaacaac tttttcaatt tcatcaagag atactttaaa gaattctttt cgttgattaa
    22261 ctttattgac ttcgtttttt ctaaaatgcg aatgtagttg attttctaat gttggtgcat
    22321 cttctgaaaa tatcattgca tgaacatcaa attcaaaagg tacagaagcg ctactaagtt
    22381 ccttaattct atccataggt tctaaccgtc tagtcattcc tattttatag acatcttcac
    22441 cgaaagatcc gatattactg atgacataaa catagccagc tctagtatta agttctcttt
    22501 gcaatacatc ttctttgaca gtttctagtt ctcttaattt ctcttccagt tctttaattt
    22561 tatcagcata gagttctttt tcaacatcag cactagcttt ttgcatgtat gccattaact
    22621 tagttatctc tgagttaaac tgtcgttctt ctttatcaat gcgtttcttt tcacgttcta
    22681 tttcacgtct taccttttct tcttcaatca tttgttcttt tattgctttt tgctgttctt
    22741 tttcatcgtt aactttaact atgtatgaat agttgagttc taattcttga agttttaatt
    22801 caagtaattc ttttttgaat tctgcttcat cgtttttaaa aagcttgttt attttatcaa
    22861 aagttcttat aattttttct ctagttgaat ctacgttaga aatagtaagt ttattgagaa
    22921 gtccagttat ttctgattct aatggtataa gcattttctt tttaatatta ttagcttctc
    22981 tattattcaa ataagaagga atattaattg caccgtctaa aataaaatcc ttttctttaa
    23041 tctttaataa agaaagtttg ttttttattt cggatgaaga agtttcatct atattcggaa
    23101 taattactga tttatagata gtgaccagag atgtgtcata tttttgatta atttcatcgt
    23161 ctaaccgctg gctttcagca ttaagaatat caattttgtt ttctagcgtt gacaagtttt
    23221 tattcaattt acttatgttt ttctcttttt cagatataaa cgtttcccta gcatttaatt
    23281 cttgagaata ttcctttacc ttactctcta aggcagaagt tttatctttt aattttttag
    23341 cttcagataa tttgctacta cccataatta ttaaaactat tccaactaaa aacaatagta
    23401 ctcccattca aaacgcctcg cttcttttat aaaataattg tcaaaatcat ataaaccctt
    23461 accgaagttg acggctccgg catgggaatt tttttaaaat acaacttttc cgataattct
    23521 aatctgttct ggcgatacaa ttctatcttc gtataagtcg tttatagaac gtaaaatgat
    23581 tgtttgattt tcgtaatctt tatatatctc tttacatgta actccgtcac cacctaattc
    23641 cacaatagca atttccccat cttctacgtc cggttgttct ttaacgaata cgaattgtcc
    23701 attcctgata acaggttcca ttgaatcgcc tataataggt actgcgaagt cagcagcact
    23761 tggaactctc tcaaattctt cctcttcgac aaccgtatca ccgtaagtaa gttctgttgg
    23821 attggcagcc gaagccgaat tgtgaacagt tgggattttt tcttttttag gaaaatctag
    23881 gacattttct tgtttttgtt cttctaatcg attacttgca aattcatagg tagcaacttt
    23941 attttcgtcg ttaagctgat tatatatagg aaggatatta tatatctgat tagatataga
    24001 taaatcaata ttcatcaaat catctatatc aacattgaat atcttagcta tctcatttaa
    24061 ggtttttaat tttggtgtat attttccttt ttcccattcg cttattgagg atgaactttt
    24121 tcttcctagt ttttcggcta gttcttgttg atcaatatta tacttttctc taagaaactt
    24181 tagattttca gcgaacatag taacacctcc ttgagttaat tgtaacaccg tttcggaaaa
    24241 aatgtaacag gtttcttaga aaatatttta gtgtttttaa agaagtattt acgcaaaata
    24301 gaaatcgatt tcaggaaaac tgaaatatgc acttgacttc ggaaaaaccg aagtatataa
    24361 tttagtcaga aagttaaaga gaggaggcga ataaaatatg gataccgcga agaaagaaaa
    24421 atatacattg agacaattaa gagctttaaa gggttattca aaagaagaac tgtcaaggaa
    24481 aagcaaagtg acatcaagaa caatatttat ttacgaaaac gatgtagata aaatgaggaa
    24541 cggaaagtac gccactctag aaaaaattgc taaggcattg ggtgttagag tttccgatat
    24601 ttttttagac cctgattcgg aaaaaccgaa atcaataaca ggtgaaacaa aacaagtcag
    24661 ctaggaggtg tgaatagtgg aagagaagaa tataaaagta ccgactcttg aagaatatac
    24721 aaaaattgtt gtcgaaacag acgagcagaa cccgaaaaca atcgcagtta ttacggcgaa
    24781 tgatattgaa tcatgcgaag gttttcgagt tcgaatgacc cctagatatg attaatgttc
    24841 tttatcacgt ggaggtatag gatcgtttcc aaaactatct tttgattgta tttgtccatt
    24901 ctttttttgg acaataaact ctgattgctg ttttttagaa atctttttac catactcaac
    24961 agcatctgat ttattatcaa atagttttgt atcttcggaa ttaccttcac cacgtacagc
    25021 ccatttgcca tttctaggag atacccattg atttttaccc ataacaattc acctcgcttt
    25081 caagttaatt ctattaagag gtgaaaagaa aacaaactga tggaggtgag attgtgagta
    25141 acaagccaaa aatcactttg aatggcacac ctaatcttca aagattagca gatgaaatgg
    25201 ctagaatacg ttctagacat tggggagtta ctgtggtggc aaccataatt gaacaaaaag
    25261 aaaagcccac acagccggca agcaagtagt gggcaccata gaacaataat attatatcac
    25321 acactcgcca cttccgaaaa gaggagttgc tgctctcctt tcaagtttgc caaagtccac
    25381 gtttcttcat tttggcaact cctcttcttg gaggtggtga cggcgagaga cgaaggaggg
    25441 atgacatgaa ggaagaatca aaaataggga ttttgaatga gaacaattac acaagattaa
    25501 ttattgaaac agaagaaggg gaaaaagtag cagaagttac attgaccgat gcaactcctg
    25561 ctgacggtta tcgtattcga ttaactccta aatatgatta accttttggt gggtgtggat
    25621 cgtttccgtg actatcacgg ctttgaattt ttccatctct gccatgaata aatagctcag
    25681 atccttgatt tttagaaatc tctctagcga tttttactgc ttctgatttt gtattagtat
    25741 gtgcagtcgc tttagaattt ccagcacctt tgacattcca accaccattg gaattaggta
    25801 caacatgttg attttttccc atagttttca cctccatttc tatagaaata ttttatcaaa
    25861 tagaaatgga gaaattcaat aaacgaaagg agggatcaaa tgacattaca agagcatcaa
    25921 cacttgatgc gaaaactaaa tcaggaatac cacgaggaaa tgaaacctag attgctaggg
    25981 gaacaatggc gtgaacgcca gaagaagtgg ttagaaataa aaaagtgact cagccgtcca
    26041 aagcaatgag tcacaaacca aaaattatac ctaaggagat tttatcacat gaataagaaa
    26101 attgaaaatc ttatcgaaga attgaaacgt gaatgccaaa agcaaggtgt ttctattatt
    26161 tgtacagccc aaaaagaagg ggaacttaaa agtctcgttt atggtgagac aacagaaatt
    26221 ttactttgtc ttgctatgca agaagaacat ttagatgaaa atctcccatt gtcagcacat
    26281 attatgcgta gaattgctgt ggatgcttac gaacaagcga aaaatgaaga agaaaatcaa
    26341 ccttcaaatc atacttttgt tattaataac aaggaagatt tagctgatgt gatgactcgt
    26401 attctcaagg gggaatttca atgatgaatg aaaaaacaat tgatctactc attattttat
    26461 ttttcacgtt agtgattgta gcgaaaagtt atgtaatctt tggcttgtta ttcgcaatta
    26521 ccatgcttgt gctttgcgtg ttagcaagca gaaaagaggt taaacatgaa cgagttagca
    26581 aatcttgaca actatttaac tgatcctgat tatgctaaac caccatatga agcgccaatt
    26641 gatgaggagg atgaagatga gtaaatctac cttagaaatg agccatcaag aatggctcga
    26701 agaccgcaaa agaggtattg gtggctcaga tgttgcaacc gtacttggat taaacaaata
    26761 caaatctcct tatcaattgt ggcttgagaa aacgggtcaa attgaattga aagatttaga
    26821 aagcgaacca gcttattggg gtaatgtttt agaagaagtg gttgctaaag agtttcagga
    26881 acgtacaggc aaaaaagtac gcagaagaaa ccaagtattt gaacatccat tacatccatt
    26941 tttaagagca aatattgatc gggaagtagt gggagaaaat gccattctgg aatgtaaaac
    27001 agccaatcaa tttctcggaa aagagtggga aggtgaagag gtaccgctta gctatctctg
    27061 tcaagttcag cattacatga acgttttaaa caaagactat tgttatatcg ctgttttgat
    27121 cggtggacaa aaattcattt ggaagcggat tgaacgagat caagagctga tcgatacaat
    27181 cactgaacaa ttagtagagt tttgggaaac gaacgttctt ggaggtatcg agcctgtaat
    27241 tgacggaagt ggagcgactg ctgacttctt aaaagaaaaa tatgcagatg tagaagaaaa
    27301 tcaaacagct ctaccatcac gttttgatga acttatcgag caaaaaagag aactcaagcg
    27361 gacgaaaaaa gaaattgaat catctattcg tcaagtagac aacgagatca tcagtgagct
    27421 aggtaaacgt gaagccagta tcggtatcac acaaagaaac attatcagct ggaaacttgt
    27481 tcgtacaaga cggatgaaca cgaagaaact agcagagaaa tatccagatg tcgcaaatga
    27541 tgaagagatt tataacgtta ctgaatcaag aaggctaacc gaaaaggaga tcaaataata
    27601 tggcaacaaa tgaatcgtta aaaaatcaat tggcagaaaa gccacagaaa caagttgcac
    27661 caggacagtt agggcttaaa gctctaatga atacaccaac aatgagaaag aaatttgaag
    27721 aagtacttca tgacaatgct aatgctttta tgtcgaatgt tatgactctt gtatctaatg
    27781 acagttatct tgcagatagt gaaccgatgt ctatcatgag tggtgcgtta actgctgcaa
    27841 cattaaatct tgggctagat aagaatttag gttatgcata tttagttcca ttcaatagta
    27901 aaaacaagca aacaggaaaa tgggaaaaga aagctcaatt catgcttggc tataaaggat
    27961 atatccaatt agcccaacga tcaggtaaat acaaagcatt aaatgtgatc gaagtttacg
    28021 aaggagaact aaaaagctgg aaccgactga cagaagagtt tgagtttgat ccaaatggta
    28081 gaacgtctga tgaagtcatt ggatatgttg gctatttcga gttactgaat ggattcaaaa
    28141 aaactgtcta ttggaccaaa caagaaatcg aagctcatcg gattgctaac aataaagatc
    28201 gcgataagac aaagttaagt ggtgtgtggg catctgatta caatgcaatg gcacgaaaaa
    28261 ctgttttgag aaatcttctt tctaaatggg gaatcttgtc catcgaaatg caagaagcca
    28321 ccacatcgga tgagagagtc caaagggttc aagaagacgg cagcattatt gctgaaacag
    28381 aagttgaaga agatattcct gaaagaaaag aagcagaggt tatatctgaa gaaaatgaag
    28441 atgtacaaac tggattattt gatgcatcta atccgccgtt aaacaaataa tgagggagct
    28501 ttctcccttg cttttctaga ggagaaatac gaatgaacac aggatatgtc aaattacatc
    28561 gaaaagtgat gaattcattc gtttggacca atccttatat gtataaatta tggagcttgt
    28621 gtttgatgaa agcgagtcat gagaatcgca agatactttt taatggaaaa gagatacaag
    28681 tgaacagcgg agaattcgtc acagggcgcg atgctatcac atctgagatg aacgaaggcg
    28741 tgaaacgtga acatcaagtg aacagcggtt ctgtatggag atggctaaaa caatttgaaa
    28801 aaaacggaat gttgaacatc aaatcaacta cgaaatacag cgttatatca ataaaaaact
    28861 ggtctttgta ccaaagcagt gaacaacaaa tgaacatcaa acgcacaaca agtgaacaac
    28921 aagtgcacac aaacaagaat gaaaagaatt ataagaatga aaagaataat aaaacatcat
    28981 cgtcgcaacc acgcaaaaag cgtgtttacg acaccgactc agtttactac attctcgcgg
    29041 aggagttatt caaacagatt tgtcagaatc aggaaatcaa aaagccgaat ctgcaaagtt
    29101 gggcagataa cattcggaaa atgatcgaga tcgacaagcg gaccgaaaac caggtacggg
    29161 gaatgattga atggagtcag cacaatgtgt tttgggcatc gaatatttta tctgctaaaa
    29221 aattgcgaga aaaatacgac acaatggcag cgcaagcaaa tcgtgattat aaaacaaaac
    29281 aaactaaaac gcttgaatac gagaaattta gcacagatga gttgcctatt tgagaggagg
    29341 cgtaggcatg gaaactgttg gggaaatcat ggaaaagctg atacagaaag tgcttgtcca
    29401 acgtggcgaa tgtcctgaat gcggacagcc tttgtatgga tggcgtacga agaaccctga
    29461 tggctcagaa cgttgtaagc caacctgtat gcaatgtggg tataaagcat tgcgagttca
    29521 ggaagactta caaacagaac gaatttacaa cgagagcctg aaagcaagag caatcaattt
    29581 tttcaaaggt ggttctgttg tgcctaatca agcgttgttt gattgcacat tgcagaatta
    29641 tcaaattgtc gatcaagaaa caagacaagc ggttgaagta accaaacgct ttgttaattc
    29701 agtcttgtta ggaaatccaa gtcaccttgt tttaactgga aaacaaggaa caggtaaaag
    29761 tcacctagcg atggcagcgg cttgggaagt cttgaagcga tcaaactacg ataaaaaaat
    29821 cttatttatc gggttacagg aaatgctgga tcaaatcaaa ttttcgtaca acaatcctga
    29881 actcagaaaa acgattgagg gatcgttgat tgcagatatc aaaacagcgg atttagtcat
    29941 cattgatgat atcggttcag aactaggaaa agatgcatca gatagtcgag cgtttggcat
    30001 aaacacgcta aattcgttct tggatgcacg acagaaccta gcaacgatta tcacaacgaa
    30061 cttgcttggt gaagaactga aaaaagctta cggtacgaga acaatatcaa gaatgtttgt
    30121 caactctgat ggatttacga tggtattttc tcaaacagca gacaagcgca taaaaccagt
    30181 gaaaggtagt atcgcatgaa taaataccgt aataaaaaaa ctgttcatcg aggtatcaag
    30241 tttgattcta tcgcggaagc agagtattac gatctagcct tgtggcaagc tgaagcgaat
    30301 ggttggaaag tgaagctcca ggaaaggttt gagctgatgc cgaagtttga actagagggc
    30361 aagaagtatc gcaagatcga gtatattccc gacttcacat tttacaaaag cggcaagctg
    30421 gtcaaagtcg tagatgttaa ggggatgcag acaaaagact ttaagatcaa ggcaaagttg
    30481 ttctgtcatc aatatcaagt gccgttgata ttagccaaaa aatatcggaa tacgttcaag
    30541 gaagagcgtt tttaacgagg tggtccatca tgacaacaga agaagtgatt caaatgcgaa
    30601 ttcgaagcct tcggcgtgag attgacgatc tggaacgaac aaaggcagtg atggtcaatg
    30661 aaacggctag aaaggcaatc gatttgcaca tagagaattt aagaagggaa atccgtagat
    30721 tggaggaatg agcgtggata aggaagcggc ttggcgaaaa ttaatgttgc tgattcaaga
    30781 tgagaactgg caagaagatg aagcagtggt tgctgaagtt cagcgtctag gaaagattgc
    30841 taacggacgt atacgaaaaa agccagacaa aagaaaacag cgcaaaggga aaatcgtcgt
    30901 tgttttacac gaaggcaaaa ttttgatgca aggaacagct agtgagctgt ctgcagaaac
    30961 tggatatacg cgtgggacta ttcgaacgta cgcttggcga aatcacaccg atcgaaaagg
    31021 gcacgaatat aagtatttgg aggaagaaaa atgaacgaaa acaaattaat caaattgggt
    31081 gtagcaggag cagtaatcgt aggtattgga gttatcggag gatttaagtt cttcgaaaaa
    31141 atcgataatg gatatgtggg tgtgcgctat tcaatgaacg gcggtatcaa agatgaagca
    31201 ctgacgcaag gtgtgaaatt tgtagggatt gacaaagtga tccaatatcc aattcgcttg
    31261 caaactatcc aatcaaaaaa tatttcagta tctacaagcg acggcaaaaa gacaacgatt
    31321 gatatcaaat atgactacaa agttgattca actaaagcag caaaaatgta caaggaattt
    31381 gggaatatca cttcggaaga tatcgaaagt ggatggttaa aatctaagct tcaaaaggtc
    31441 gctcgtgaag tttatgcgaa atatagtctg cttgatgtcc tttcaggaga ttcctctaaa
    31501 gttgaagctg aggtattaac gaactttgct aaatcagttg aatctaaagg gtttgaagtc
    31561 gaagacgtaa cacttggtgt tccagatgtc gataaagaaa cacaaaaatc aatcgatgcg
    31621 atcattcgag ctggtcaaga aaatgaaaaa gcgaagctag acgcagaaac tgcaaaaact
    31681 caagctgata gtgaagctta caagaaaaca aaagctgcag aagcagaggc agaatctaat
    31741 cgcaaagtcg ccgaatcagt aacagacaat ttgattcgtt atgaagaagc tcaagctcgc
    31801 aaaaagcatg gatgggtaac agtaaatgga gcagatactg tagttacgga tgaagcaggc
    31861 aaataatatg ggattcttta tggctaaaat tctcttgttc ttaggtttag taggagcagc
    31921 atatctcgtg tatgcgctcc tttcccaaac tgatgacaaa gaagatgaca acaacgatga
    31981 aatgaaattt taggaggaga aataatggac gaactaatca caaaagtaga gcagtgggct
    32041 aaagacaagg gactggatca agcagatcca aaagcacagt ttttgaaagt agctgaggaa
    32101 ttcggggaaa tagcttcggc gatggcaaga agtaatgatg aactatttaa agatagcgta
    32161 ggagacgtta tcgtcacgct gattatcctt tccatgcaaa aagggacaaa cgtacaagag
    32221 tgtttagaaa tggcatacaa cgaaatcaaa ggacgcacag ggaaaatggt agatggtgta
    32281 ttcgtgaagt cgagtgattt ggaggatgtg aaatgaaata cgaaatacca ctaagtgaag
    32341 cgggcattca agcaattatc aatggtcggg aggttaacat agaacttcct gatggtactg
    32401 aattagtcat cagacaaagt tatttgaaag atatggcagc tccagtatta attgatcgtt
    32461 ttaacgtgac tgattctgtg gtagagaacc acttaaaaga atttcgatca agtatagacg
    32521 acactttcag attagggagt tgattgacaa tgaacaacag acatcgcaga ataacaaaac
    32581 taagaaaaca ggaactgaat gtactaaaga caaagtttga aaaggaatat ggaatttcag
    32641 cagaagaaac atataaagtg gcaagtcagt ttgttgctga tgcaagtgat gctattcgta
    32701 agtttgggat ttcgatatta aatgatgatc gtaaatggga ggaaatgaga tgaaactaaa
    32761 agacggattt tacgctagta gtcacggcat cggcggttta atgctagata tgccgacaaa
    32821 gaaccctaaa acacgtaaga aaccaaaagt caaagtcggt gacatggttc gctgtgaagc
    32881 agaagagttc atttatccgt ttcgtggata tgtagaacac gtctataatc actcagcgat
    32941 cattcgtatt gaaaacacaa tggaatgcga taagtggtta gcgaaaagca aagagaattt
    33001 agctgtagcg agattggtgg atatggaggt tataaacaat gaagtttaaa atctttgaag
    33061 aggacactcg ttataaatta gaaaaagaat taaacgattt tgcgaaaaac aatgagattc
    33121 agcatatatc tttagcaact tctaagagag gttatgcaaa ttactatgca gctgttgtga
    33181 gctatgtaag tcgagaagtg taactcggca aataaaaaaa gccggatcgc tccgactgat
    33241 tcaataaatc caacacattt attatatcac ataaaggagc ggtttgactt gatgcaattg
    33301 ttacgagagg tagatttcaa acagacaaga tgtaatgcga gagatgtgct gaagaacttt
    33361 cggcgtttgg agcggatggc aggtcgctct ttgatagata ttaagtcgcc gattattacg
    33421 gatatgccga aggcaccgaa gcacggcaat aaggcagaag acgcgatcat tcaaatgatg
    33481 gatatagaag cggagagaga cgcgattcta gtggctttga tggctcttag tctgattagt
    33541 cgtcagatac tctactacag cttctgtgtg ccagacagct tctcaaacta cagaattagc
    33601 cgtgaagtgg gttattcaga aagaagtata caacggatga aatcggaagc tctaatagag
    33661 tttgcagaag catataaaca cggaagaata attgcttata aataggggga ccatataatg
    33721 tggaaagatt atgtatcgtt gaaagagttg aaaaaagatc ttgttttcaa aagaattgta
    33781 gaatggtcag agagtgaatt aattttagaa gatggaacca aaatggaagt tgtatgtagc
    33841 gaatcagatt gctgcgcatg ggccgaaggt gaattcaaaa atgtaaagct tgatgcagtg
    33901 attacagata taaagatttt tgataaaggt aaccgtctct ataatggtga cggacatacc
    33961 tcttatgctg aagtcgttgt ttatcataat cgtaatgaga tcgctaaagc agaatgcaca
    34021 gcgaatgatg ggaatggcgg ctactattat agtgtttgtg ctttaaaggt caaagacaaa
    34081 ctttgtatag tgactgacgc ataaaaaaat ggcggttttt tggcggaatg atggcggttt
    34141 ttagccattt atcagtgata ttatggtagt gtcgaaagat tagtgatagg tctgagacaa
    34201 aataataata aaaggaacat cgttttatta ttgtttcaca attaagcttc gatagacagc
    34261 agcggaaata ttaagaataa ggatgtgaat tttaactcct tctaaattgt tcttattatc
    34321 tatcatccgt tgctgtctat tgttacatac agatcgctta ggcggtcttt ttattttggc
    34381 cgaaaaccta cattttcgat ggccgattat tggaggagga atagcatgtt caaactatct
    34441 gaaatcatta agaagtccga cgttgagaaa ttagagatgt taaaaaagaa gttgaagaaa
    34501 tagcagtctc ttcgtgaggc tgttttattt tgctcacaaa aatagaccac tatcgggtaa
    34561 tagtggtcag gaattaaatg aaaaagatgt tagggttgtt agctaagtat aacatcataa
    34621 cgcttacaaa acaatgcaag aaggataaat tattatgaga acttactggt atgtgtcatt
    34681 aaacaataaa tatccgaagc caatgaaagg acagcatagg cgtgtagtca tgtctgttca
    34741 aatgaaggcg aagtattcga ttgtagaaat gatcagagag gcaacgccag tagagattga
    34801 ttattgcaag ctagtctatt gtgggtgcgg ccgttggaaa gaggatcatg tacaaaaaaa
    34861 tatcagcaag tacatataga gaggcggtga ttaaggatgg aaaaaagcga tacgaaagcg
    34921 aacagataca aacctactgc tgcagagaaa aaactcttgg aagtattgat aaatccagat
    34981 aacttaggca aaccggtgca agagttgtgt tcactggcga aaataggtag gaccaaatat
    35041 tacgacgcca tgagcaaaga tggctttgtt gatctagtta acgaaacaac aatggatctg
    35101 atcaaaggaa aagcttctga tgtccttaat gccacttaca agtatgcatt gactgaaaaa
    35161 ggtcatcagg ataggaaaat gattctgact attgctggaa tctatgcaga caaacaagaa
    35221 ctcaaacatt ctggcggcgt cgatatccga aaacagtatg agaaaatgtc cgatgaagaa
    35281 ttagaagagt tggtgaaacg gtatgaaaaa atcaacgact cttaatcgtg ttgagtatgc
    35341 cgttgttcaa agagagctag ccattcgaaa agctaggaaa agtttttggc tattctgcca
    35401 gcttctttat ccagagtttt acaaagatga tcggttgtat ttgaaagatt tatgtcatac
    35461 gctacaagat ttttacgaag ataaaatcga caaaaaaatt ttggttatta acatgccgcc
    35521 tcgacatggg aagactttta cagcgcggct attcgtttta tggatgtttg gacaaaatcc
    35581 aaagacgaaa attattaccg gatcttataa ccaaatcctg tcatctttat ttgcgcaaca
    35641 aacacgtgat ggaatcatgg ttgaaaacga aaatgttaag gctgaatact ttaaagatat
    35701 ttttccagag gtgcaaatca aatatggaga tgctgcaaag ggtttctggt ctttagatgg
    35761 ttcagaagaa aagaattatt tagcgacttc tcctggtgga acatccactg gtattggcgc
    35821 gaattatgta attgttgatg acatcattaa aaccgcagaa gaagcctata acgagcgtgt
    35881 tttagattct cactgggaat ggtataacaa cacgttggcc caacgaatgg aacggccacg
    35941 taaacagata ttgattatga cacgttggtc aagtaatgat ttagccggaa aaatgttgac
    36001 gagacgaaaa aataatgttc atcagatctg ttataaagca gtacaagaag acggctcgat
    36061 gttgtgcaac gagattatga cccacgatga gtacttagat gtggtacaag aaatgaatgt
    36121 agatattgca gaagccaact atcagcaaga accaattgac caaaaaggca ggctatatca
    36181 gaagtttctt acttatgata cgttgcctga taacattatc aaaatatgga actacaccga
    36241 caccgccgac aagggtgccg attactttgc gtctcctgtt tttgctgaga cgtctgatca
    36301 tgatgcttat attatcgatg tcatgtatac aaaagagccg atggaaacaa ctgaaatagc
    36361 ccacgctaat atgattattc gcaatcgagt taataaggta cggattgaag gaaacaatgg
    36421 cgggcgtgga ttcagaagaa attcagaaag aattacaaaa gagcgaggct atcgaggtgc
    36481 agtatttgaa gactttcatc aatcggataa taaactgtct agaatactgg cgaatagtgc
    36541 ttgggtggaa aatcatgttt actatccaga tgattgggcg acacgttggc cggactttta
    36601 tgaggctatg gttagttatc aacgtgaagg taagaacgct catgatgatg ctccggatgc
    36661 agttacagga attgcagaaa cgattataga agcagatgac ttcgagttta ttgcttatta
    36721 ggaggtgggt ctttgtttta ttctggaatc acattgaaaa aatacaaacg tttaagaacg
    36781 aaatattcaa cgcaaatcga agaaggatta ttcgatccta acgcttttat ggaagatatg
    36841 aaaccctttt tcgatgatcg agaaagaaag tatcttgctt atactagcga gaaaaacgag
    36901 atcgacagtc gtgagaaacc aaaaacaaaa atcattaagg tcaataacaa gattcatgcg
    36961 ggaatgtatt cagtggtcgt tgatcaagca gttaaccatt tcacaggaat accaattaaa
    37021 tgggattatg atgtttcgga acagaaaagg acattcattc aacgaatgag agacaaatta
    37081 ctgggtaatg atatcagcgc cccttctacc ccagaagaat ttgaaacact cacgagacaa
    37141 ttaagtacta tgcggtttgg aatgttagac cccgatactg caacatttca aggagcgaca
    37201 gggcttgctt tcagattact ggagcctgtt gagacaaatg atggttggga actaagagca
    37261 agcaacattg agccgtggaa agctgaaaag tacgaaaacg gcgcagtgta cattaaagag
    37321 aaatacgatc catatcaaaa gaagttttat gaagagatga aggttgtcac gccgaaatca
    37381 atatttactt atgctcgata tactgattac cctggcacgg tacaaggagc atttaaaacg
    37441 ctgggtaatg ttcctaatcc tttaggcgtt atcaatctta cggagtttaa aaacaataca
    37501 aaccgttact gtgactttga agttgcagag gagattagtg atgctattga tcgtgtttta
    37561 tctgatcagc agaacgagat tgaacaattc aagttagctt atatgctgat cactggggca
    37621 gatttgtccg aggataaagc caagaagatg atggagcaac tagggatcat caatctgaaa
    37681 gaccctaatg cgaaagccgg ctacgtgaca aaggatctac aaaaggattt caacgagtat
    37741 cattttgatc ttcttaaaaa gcaattctac acggtgtgta aagcaattga tttcaatgac
    37801 gaagtcttta agtcgaatag ttctggggaa gcccgaaagt ggcaaatcat tagtttagaa
    37861 gctaagacaa ataccaaaga acagtacttt cgagaaggat tgaaagagtg tgccgaggtt
    37921 atggctgctt atttggattt tgccgagaaa gttacaattg atccggaaaa gatcattttc
    37981 accttctctc gttcgcttcc aacagattta agctacctag ctgaggcatt gcctaagttg
    38041 gcaccatacg tttctaagag gacgattcaa agtcagatcc cgttcgtcac agatgttgat
    38101 tatgaaaacg aaatgattga cgtcgaaagc agacaatctt acccagacgg cgagtatgga
    38161 ggtggcatcg ttgagtcaaa tagaaacgaa gtactggacc aaacgtcgag aactggaaga
    38221 tttagcaaga ctcaaaatgg aaaatcaaac gctaaagaaa ctaagtagtg tctttcctga
    38281 tgcgttgaaa gaaattcaag cggagttatt atcccaagct gatttacacg atattaccta
    38341 tgctgagatg atggaatttt atagtacaag tgatcagaaa aaatatcgtg aatacgttga
    38401 aaagaactac aaatcactga agatgtatga tgcaaaatac aaagagttca tcgaagaata
    38461 ctttccttct ttcgactacg ccaaagtgaa tcggctgctt caaatgaggt cagatatttt
    38521 tcgaattctt gcagagagtg caatagatgc agatgtgaat aaatattttt cggatcggtt
    38581 agaagatatc ttgcaacgtt cgtatgtatc aaacgcaaac gtatttgccc agattttgaa
    38641 cgtagatttg ccgaattact tatcaaagga agaacttgaa cgttacctga actatccttg
    38701 gtcaggtaag acattctcgc gtcgtttatg gggcaatatt tcatctctag aacaaaagct
    38761 atctaacgcc attacaacta gtgtagcaag tggcgaagga gttctcgtgg cattacgaac
    38821 aatgcgagaa gacccagaaa tatgcgatat gttcaaaagg gaggaatcga agtacaacaa
    38881 ggcgatcgaa aatcttgtga gaacagaata cgctaaattc gctcaagatg gtattgagaa
    38941 atcttatatt gaaactggcg tagacgaata caatgtctta actgcaaaag atgaaaaggt
    39001 atgttcaata tgcggtggca aagcaaagaa caacccatac aagttgagtg aagcgatcat
    39061 tggtgagaac cgtgcgcctt ttcatggccg atgcagatgt acagatgttc ctaatatgcc
    39121 gaaattagga aaagatattg acgaagagta tgagcgttta tttggcgatt tattagatga
    39181 gtttgcacat gattcttttg gaattaattt gaaacggagg aagtagaatg aaagattttt
    39241 ttgaagcagt actaacaatt aatgtaaatg ctgatattgc agaagcctac aaaacagcta
    39301 ttgagtctga gaaccatcct aatggcttga gagaccattg gaatggcaat tatgcctacg
    39361 tggttattgg cgatcaaact gttaattatc aagataatac tccagttgat aagaataccg
    39421 ttaatttaac gattcaatta ttatctcatt cattaccaaa tttaaaagaa acagttgatt
    39481 ggtatgaaaa tatgggatgt attgttgtta gaactgacta caaagaagga aagtctagta
    39541 attaggcttt tttattttgt ccgaaatgac gttaaactag cgcaatactg ggcttggttg
    39601 aatggtgggg cgcaactatt aaaactcaaa gcaatgcggg gcgtgaaaac gaatcgtggg
    39661 gcgaaaggag aatgattatg aaacacaaat cattaatgcc aatgaatttg caatactttg
    39721 ccgaaggtga cgatcaaaag ttttcttttg atgacttcaa atcttttgtg gaatccaatg
    39781 aagaagctca aaaatttatt cagtcacaat ctcaaagtgt tgccgacaaa caattggaag
    39841 cttggaaaca aaataactta gataaaatta aacaggatac catcaaggaa tatgaggaat
    39901 ctaagaaaaa caagtcacct gagcaaattc aactggaaaa actacaagct gaatttgaag
    39961 cagaaaaagc gttgcgtgtg acaagtgata ataaagcatt tgttgcagaa caaattgctg
    40021 gattagaact agatggagag ttaaaagagt ctatttctca atttatgcta aataatcttg
    40081 ttagttcgga tacagatttc actaagaatg ctgttgaagg ttttacaagt gttttgaatg
    40141 caattaatga gaaacatgca gatgcattaa aagaactaca aatgaagtct gcatttggtg
    40201 gaactcaaca atcgaataac caggttcagc agaacaatga aacattaaca aatccagaag
    40261 aacaattagg acaaattctt caacaattta actaggagag tgaaaaatta tgaaaaaaac
    40321 atctttaaat aatttagagt atttggatat ttcaccagcg attaatgcta tgcaagtacc
    40381 aaatacacct tttttaagct atttacttgg tgctggaaaa acagagccag caaactcgac
    40441 agaaattaaa tggcgtgaat atgatatcaa caacgatgat tcttctgaaa aacttgaggg
    40501 cggagaatat ccagatgctg aatcaggtcg aacttggttt aacaactata ctgaaatttt
    40561 tagaaaatca acctctgtat ctggtacatt agatgctatt aatgtgaatg gagtcggaaa
    40621 tgaattaact aatcaagtag cactacgtgg tatggaaatg aaaattgatt tgaaccgaaa
    40681 attgattact ggtgtaaaag ctgatgaaaa tggttctaaa ggtcgtcgaa tgaatgggat
    40741 tttgaacttg atcaattcag caaataaggc agaaacagcc actgcgggtg cagtaacaag
    40801 aaaagatatc gatactttat ttaaattgat gtatgaaaaa ggttatatgg gagaaaaact
    40861 atgcttgatt tctccagata tgcaggagtt aatgactgat gagttagatg gaaaatcaac
    40921 aaaaattgtt cagttcgggg aaagagtaac ttttggattg caaattggaa atatcgtgtc
    40981 taattacggt acaggtattg ctctactaga accatcattg ccaaaaggaa caattgccgc
    41041 aatcgatact aattatgtga aactacgtcc attacgtgaa tggagagcag aagaacttgc
    41101 aaaaacaacg gattctagac gtatcggtct tgtaggtgaa tactctcttg aatacaatgc
    41161 ttcaaactct ggggcaattt taaatttaaa gtctgaataa aagggagtta gtactccctt
    41221 ttttgatagg aggaattaca gtggtaaaaa aagatgaaac taaaaaagat gaagtcgtga
    41281 aatatagagt aggtaaaact aaaaattttg ttgggtttgt tcatcctaaa actcgtagat
    41341 ttatcacagc agattcaaat aacgaattta tcatttctat agatgataaa gaagcaattg
    41401 caattttgga agatgcaatt gatgttaatg aaatttagga agtgatctga tggatgaatc
    41461 gctaaaaacg gaaatcattg agtctacaaa agaagatttt ccagatttga gtgaagaacg
    41521 cataactaat ttattagaaa taattttgct agaaattgaa tcatacaaca cttgtaaaaa
    41581 tgatatttca tgggaaaagt taaaaagcgt gattagtgaa gtgttgtata aaataataaa
    41641 aaatgaatca gaaaaaacag tatcttcagt tagacgtggc gatacaacga ttagttatgc
    41701 ttcaacaaca aatgatgtta gtgagttact tctaggctat ggtgatttga tacgaagagt
    41761 tattggttgt ggaggattgg agttttttta atgaatgaag cagatatttt agaaactact
    41821 tatgaagata gttgtattat tgaaagactg acggacattg aagattctaa tacaaatatt
    41881 actattcaag attacaaaaa agtatatgat aatcctattt cttgcgctct ttcacaaggt
    41941 caaatcgatg gactagcagt catagaagat ggagagatgg taaatgtttc aactgacaca
    42001 tataaattat ttgttcatcc taagattaaa ctaaaaaaag gagatcgaat aacaataact
    42061 caaaaggcca gtggcttaat tttttctcta tttgctacta agccttttta ctatcctagt
    42121 cattgtgaag tgaatttgat aggaagtgag aaaaatgggt aatctcaaat atgaatcaaa
    42181 tgcagaaaag atcattgaga attttaaaaa tatgactgta attgctcaaa aagaaggaat
    42241 atccttcgtt aacgattcaa tgaataaagt cgttagttta gctaaaccat taactcctgt
    42301 aaaatcaggt aatttaaggc gaggatatcg tgtagtaaaa gctagaaaac tatcaagcgg
    42361 tcgaattgtt ggagcagtta taaacaatga acattatttt aaatatgtag aagaaggtca
    42421 taggactaaa aatggtggct ttgtcaaagg gaaattcatg ttaactcgtg caacgaatct
    42481 tgcaaatatg tcttatattc ctcgaagatt taaacaaatg gcaataaaaa tcgttaagaa
    42541 aggaaagtaa catgaaagat gaaatcattg ctgcaatcag tagcaaatta aaagaaatct
    42601 atcctgatgg gacaatatat cttgattcag ttatgcagtc aactaaagat ttttatttcg
    42661 ttttatcagt aatggaatct ggaactgaaa atgtaggaat tgatattcaa aatgtttctt
    42721 tcttaattga tattgcattg attgataata aacctaatag aaatttaatt aatgaattag
    42781 tctcacgttg tgggactttt tttaatacga ttacaatcga tgagcaaata ttatttccaa
    42841 aagcctattt acctgatgaa gcagatggtg ttcaacatat tcgttttaca ttagaatttc
    42901 cacaatatat tgaatggagt gaaagataaa tgggagaaaa aagaagtaaa accggaatta
    42961 tttctgtcga aaaacctact tggtttcctt tggaagatga gacagggaat ttcccggtat
    43021 atggtactgc gttgccaatg ggaacagcag taagtatcaa accaacagct aattatgaaa
    43081 caacacaaga ttatggggat tcagtggttc aagatcaatt tacagctttt ggtggtgcag
    43141 aagttgaact ggaagcaaat ggatatactc ataaagtttt atctacaatt actggaggga
    43201 aaattgttaa aggtggtgcc ttgcgttctg gagaagatat tgcgcaagat ggtgcgtttg
    43261 catatagacg taaaaaatcg aatgggaaat accgttatac ggtcttttat aaaggacagt
    43321 ttgctctaga ttcagatgaa acgtcaacga ttgaaggaag taaagtaagt tttactcatc
    43381 caacttggaa gggttcattt gtagatgtac caggacttgg atatatgtat tcagttgatg
    43441 aagatgatga aggcgtggat aaagcaatga tcggaaattg gtttacaaaa gtagcaattc
    43501 caattgaaga agcagaactt tcaggaggta cagaataatg tcaaaatatc aaacaacgat
    43561 taaattaacg aaaaaagatg aagaaggtaa atatgagcaa gtacaattta aatctgctga
    43621 atttttacca ggaacagttg tagaagatgc tgcaggagtt atggaagaaa tgcaaacagc
    43681 gactgataaa caatcagtta aaaaagcttt aagtcgtgct tattcattta ttgcagatac
    43741 tttatttgag ggacaattta ctggtgaaga ttattgcaaa ggaattgatg ctcgtgagat
    43801 tgcctcattg acaggaaaat tattgaagtc tgttactgca ggttttgatg aaacttatac
    43861 agagacgaaa aaaaagtaag tgaggcgctc aagtcacctt catttaagta ttcgattact
    43921 taccgagaat tagatataaa gacgcaatta ctcgaagcag gttggacgtt accagaaatt
    43981 gaacgtactg acttggatga gttaatgcgt ctttttgctt ttagagatgc ggtaaaagag
    44041 catgaagatg ttgagtacta tgataatttc actcaatttt aggaggtgat actttgaata
    44101 acgatgacct aattctgaag atgatactag atgaatctgg ttttactgcc ggtatgaata
    44161 atgctgtcaa aaagttgaac tcttttgatg aaacaatcga aagaaaaagt agaaatggtg
    44221 gcagttcatt aggtagtatt tggaaaatat ttgctggaag ttttctagct agcggagtaa
    44281 ctagaatcgt aggagctggc tttgatctaa tcaagggttc cataagtgga gcggttgatc
    44341 gagtagatac gatgaataac gctctacgaa atttccaaaa tatgggattt agtaattcag
    44401 aaattatgaa gaatatcgga aagaatgggc ttttatctca aggtattcaa ggacttccta
    44461 ctgctttgaa tgatgcgata agtcatgttc aacttcttgc ttcttctaca ggtgatttaa
    44521 ctcgttcaac tcaaatattt aaagctttaa atgatggaat tcttggtttc ggtggttcaa
    44581 ctgatcaagt taatgaagct gttattcaat tatctcaaag tttctcaaac ggaaaagtag
    44641 acgcacaaac ttggaactca atgatcaacg ctcaacttgg acctactctt tctgctattg
    44701 ctaaaaagat gggaattaca atgggagatc tgaaagaagg tttatctcaa ggtaagattt
    44761 ctgttgaaga attccaaaat caattaatag aaatggatac caaaggtggc ggaggactta
    44821 aatcattaag tcaaatcgct aaagattcta ctaagggaat taaaacctct atacaaaatg
    44881 caaaaacagc tgttacacgt ggtgttggtg aggtaataga aggattaaat aaagcattag
    44941 tagattcaga tttaggtgga tttaagggga ttattgataa agttgccagt tccatggaat
    45001 cttttttgaa agtaattgct gcaaatattc ctagagcagt gtctttttta agtaatcttt
    45061 ttgatgcagt tcaaaaattt ggctctgcat tgaaattcat gatgccattt ctggttcctg
    45121 caactactgc ttttggcgca ttaatgtttc aacttaaagg aataccaaca attataaaaa
    45181 gcttcaataa ttttaagaat gccataatcg gtgttggaaa ttcactaaag attatggggg
    45241 ctatagccgc cgcaaatccg tttgttttga ttgttggagc cgttgttgga gcgattgctg
    45301 tatttggcta ttttatggca accaacgaag aggttagaaa caaagttata tccgtttgga
    45361 atgatgtaaa agattccgta cttggtgtat taaagaatat aaaagattgg ggaattgata
    45421 cttggaattc tgctaaagaa atggcatcaa atgctgttga gagtgtcaag gatgcttggt
    45481 ctggaataaa ggaatggttt tcaaatactt ggcaaggcat taaaaatgga gcaacaggtt
    45541 tatttgataa aacagtagaa acatctatga atgcggttga tagtgtaaaa aacgcatggt
    45601 caaatacaaa gcaatggttt tctgatattt ggcagagcat aaaagattca gcaactgaaa
    45661 aatggaatga aattaaaggt tctatcatgg aagttgctgg tccattgatt acaggtttaa
    45721 agaacgcatt cttgcatgtc actttttatt tagagacctt atggaataat ctagttgaga
    45781 ttggtaaaaa tgtttttgag attttaaaaa atgttatact tacgccagtt ttgtttatta
    45841 cctccatgat ttctggtgga tgggaagaaa caaaaaacaa catgattggt gtatggaata
    45901 atattaaaga aagtgctcta aatatttggg agtctataaa aaatattttt gttagttaca
    45961 ttacaaatat ttattttgct gcgcttaata tttggacagg gttcaaactt actttgataa
    46021 acatttggaa tgaagtagta agtcaagcta aatcaatttg gattaatgta aaatactttt
    46081 ttattaatct ttggattgac attaagtatt ttgctattca aaaatggatt gaattaaaat
    46141 tcgggattat tcaaacttgg attgatttaa aatataatgc tattactact tggaacaata
    46201 ttaaacagtt cttcaaagat acttggcaga acattaaaga tatagcatac aatacatgga
    46261 tttctataaa gaattccatg atcaatactt ggaataacat caaggaatct ttctggaata
    46321 ttgttactgg aattgttaac tccgctgaaa atgcatggac taatctaaaa aatggtgttt
    46381 caaaagcaat taatcgggtg aaagaaatct ttgattcatt aagggaaatc aatttattcg
    46441 aaatcggtaa gaatatcatt gatggactta tcaatggtgt agtagaaaaa tggaatgcat
    46501 tgaaaaagac tattaaagga atagctggaa gtatcaaaga ttctattaag ggtgcattag
    46561 gtattcattc tccatctaga tggatgaggg atatggtagg taaaaatatt gttcaaggta
    46621 ttatcgttgg tattgataaa gaaaaaagta aattggatca gacaatgact gatttagtga
    46681 aaactccgtc ggttcaacca gttattacag ggtctaatag tcaaccagtg gtacaagcta
    46741 aacaaaatac atcttcaaat gcagtgaatg aaattcactt gcatttaaat gtttatggag
    46801 atctacctga ttcgatgatt aaacaaatcg ccaagaagat gaaaacagaa ttgacgagac
    46861 aaatgaaacg agatgctgat gcagtaggag ggacattata tgcaacttaa aagaggacaa
    46921 ttttttatca atcaacatta ttcttctgag tttaacgtat atattcaaaa taggcctgcc
    46981 tctgtttcag ctagtcgtgt aattgaattg agagaacgtg aaggcaatga ctcaattatt
    47041 atcgataaag cctattacaa aaacgttact agaaaaattg aatgttatta caaagcacca
    47101 tcgattgatt tagtgcagga atgggaagat cgaattactg aatggttaga tatgaactct
    47161 tacagtgatt ttattcttta ttacgatcaa caatatatct atcaagctat agtaaccgaa
    47221 gcgccagaat ttaaaggaac aagaaaaaca gggaacatag ttccatttga atttacagtt
    47281 agtcttcgac cattcaaaga aaattatagt ggtcgttttg ctattcaaca gataaaagct
    47341 ttcgagttat ttaatccaga gaagtatgct tcaaaaccgc ttattaaatt gagtggttct
    47401 ggagatgctt ctttttatat taataatgat aaatatgatt tgaaactatt agatagagaa
    47461 ttatatatag attctaaact agaagagtct tatcgaaagc tagatgacaa tttagaacat
    47521 caagatcatg tcactttatt tttagatttt ccatttctat accctggaaa aaatgaaatc
    47581 aaatggacga ataacataca ttcgtttgag ataataccaa ggtggtggag aaaagtatga
    47641 taccaagaat atatagtcct accgagacag atttttctac gaatggttta gggattttga
    47701 aggacaccac aaaatgtgag atatatgaag tagcaaatgg aaaatatgaa ttagagttgg
    47761 agtatccatt aggtactcga tttgatgaat attttgaaaa tgactatcaa ataaaagcaa
    47821 agtcaaatga tcaagaagag tatcatatct tttttattga tgataaagat attgatacct
    47881 ttttagatac cgtaactatt tatgcccaga gtcgtacaaa tcggcttgga agacgagcgg
    47941 tcacttttgc tggagtcgac tctaaaactg gtcgagaagc aatggcaatt attgaaaaca
    48001 atatggataa aaaatcagat atacgcttat attctgatat tacaactgta tcaagtacaa
    48061 cttttgaagc aagaaatgtt ttaaattgta ttgctggtga acaaggatct ttacttcagt
    48121 attggggcgg agaaattaaa cgtgagcctt ttaagctatc tttattaaag cgaagaggtc
    48181 gtgataatat tggcacaatc cgatatggaa aagatttatc tgggttaaaa gttaagttag
    48241 attggacagg cgtgaaaaca agaattattc cgtatgctga tcctcaaagt gatgcaggta
    48301 caactagccg aatttatggc tcgccagtag atagcgaata tattaataat tatcctgatg
    48361 tatatacaga acacgttcaa ttcacagaag aacagggagt taaagacgtt aatagcttaa
    48421 ataaaatagc taagaattat ttcaaaacaa ttaatccagg ctgtgataaa ccgaagattt
    48481 ctattaccgt tgagttcgat aaattaacgg acaccgaaga aggaaaagaa ttcgctaaga
    48541 taagaaatta tgggttattt gatacgttta aaatatatca tcgaaaatat aaactatatt
    48601 ttgaatcgaa agttagcggt gttcaatatg attcattatc tgaaaaggtt ttgaaattgg
    48661 aagctgggga tgctcaagtt gctttttatc aacaacaagc tgttactatt caagataaat
    48721 taaaagatta tgctacgaat aattatatga gtagttttaa tgattatgtg tcctctatga
    48781 ttgcaggtca aggaaatgca ggcggttatg tagttttatg gccaaaagaa aaaccttcaa
    48841 atatttttat aatggatagc cctgatttaa acaaggcaaa agaagtatta agaatgaaca
    48901 aaaatggaat tgccttttct aaaaatggtt ggaatggtcc ttttaattcc gcttggacat
    48961 tggatagtat attcaatgct aattttattc aaacaggatt aataaaggca gatatctttc
    49021 aaaactcttt taataaaact ggagatgtat tgaaattagt taatggacta cttcaaattt
    49081 ggaataacaa aaagaaaata atggagttaa ccaaaaaagg aatggagttt tggaattcta
    49141 atagttcaat tggaacgatt ggaacaactg attctgctgg taatcctttt cctggagctt
    49201 ctactcccac acctattgaa gataattctt tagttattcg tacaaatgga gacggcaaat
    49261 atattttgat ttctcctaaa gttggtaaag gattagtttt attaggaaat ggtaaagcaa
    49321 tttattttgg agacttagat gtacaaggca aactcacagt taacggaaaa gaaatcacag
    49381 ggaacaacag tggaggaagt gatcctggaa ctatccctcc tcaattgacg acggaagctg
    49441 aaaaaagagc atggaaaatt tggacaatgc tgaaagctcg tggctattct gaatatgcag
    49501 ctgcaggtat tctaggaaat attcaggggg aggttggagc aagtatgaac cctgatacag
    49561 aacaacttgg tggtccagct tatgggattg ttcaatggga tggttctgct tatccgttag
    49621 tcggatcacc aacttggaac ggacgagagt atgttcagcg tttgatgaac accgcaggga
    49681 ttcaagaaga ttatcgaagt attgaagccc aagtaaaatt attagattgg tgtatgttca
    49741 acggtcaatg gctcggaaaa gtaaatccaa ccacagtatc aggatttaaa tcgatcaatg
    49801 atgccaaaag tgcagcgtat gcttttgaaa tgaacttcga acgcccagct tctgcacatc
    49861 cagaacgcca aaattatgcc caatcttggt ataacaaatt acatggatta actagtccag
    49921 aacctggagg gaatttcatt tgtccaattc aaaaaccagt gacagttact tcagaatgtg
    49981 gatggagaac tagtccaata aatggcggcc aagaatttca taatggaatt gatcttgtaa
    50041 atggaaatcc taatacacct gtttttgcag cattagatgg ggaagttgtt caggctggtg
    50101 ctaattatta tgactggtat ggtaattacg tggttattaa acataataat gggaagtgga
    50161 caggttatgc tcatttgtct cgtattgatg tttctgttgg acaaaaagtc cagaaaggtg
    50221 ctcaaatagg cttgatggga acaactggtc catctacagg agaacatcta cattttcaaa
    50281 ttatgaaaaa ttattggcca cagccagttg ttgattttga gaatccaaga aattatatcc
    50341 aattttaagg tggtgattct atgagtaaat ggaatgtcgt tttaagtaca acagaaccat
    50401 ataattatgt ggggatgatt caagttcgac aaggcaataa gaatacagag gttatggaag
    50461 cgactatagt tgaaaatggt cttccctacg atttatcaga atgtaaggta tattttgaat
    50521 cagttgtagg tgggaaatat ccagtccaat tagaaacaaa aattgtggat gctaaaaaag
    50581 ggaaaattaa
//
LOCUS       DAFBVQ010000013        46152 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.013, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000013 DAFBVQ010000000
VERSION     DAFBVQ010000013.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 46152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 46152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..46152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.013"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            46..2211
                     /gene="acm"
                     /locus_tag="LLC22_000953"
     CDS             46..2211
                     /gene="acm"
                     /locus_tag="LLC22_000953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Acm"
                     /protein_id="HBK5434247.1"
                     /translation="MKKCRNIILSMLFIITNITSLIPVHVYADAGRDISSNVTSLTVD
                     PTNITDGGNIKVKFSFDEKKQNIQPGDYLWINWPSEGNIRGEGFQKEIPLMIENKNVG
                     TLTVRKDSAQVVFNENIKNLDSVEGWGQFEIQARNVTDTGEENTGPFTVTSGDKTATV
                     NVTKPASGSSSSVFYYKTGDMLPEDTKHIRWFLNINNNGTYVEQPVKISDEIQSGQRL
                     DPSTFEINQIHLGEQKVYRGEEGIQQFLQDFPSATFNFSVTDNYIEITIPKNFVNLRK
                     IMVSYKTIIENPEQINFENHSEAWFKEFNKPAVDGESFNHTVKNISASGGVNGTVRGE
                     LKIFKYINDTEIGIPNVTFELRRADEQPIQGQSSILLTSNEQGEASIKGLQVGDYVVK
                     EKEAPNWIDFDPLSSNELKFSINENDTEGVSLPIYNKKKVTNITATKIWNGGTTPRPS
                     IYFKLFRASTNNWEPVPDAETKRLDNGITSVTWEDIQQYDDSGNEYTFKVQEVDQNGN
                     DYVPSGYQKIENGLVVTNENKEVISVSGQKTWEDNENQDGKRPTTITVNLLADGQPIQ
                     HKEVSEKDDWRYRFTNLPKYRDGQEIIYTVTEDNVPEYSTTIDGYNIKNSYTPEKTNI
                     SIPGSHITPWKNFPEKTEREKIRNLFSQKLQIFAHTGESSEQRSNYISKRAVPKQITN
                     KSKSILPKTSSKKSSFAVIIGLLIVTICAGIFLQKYKKV"
     gene            complement(2483..2968)
                     /locus_tag="LLC22_000954"
     CDS             complement(2483..2968)
                     /locus_tag="LLC22_000954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289239.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA synthetase associated
                     domain-containing protein"
                     /protein_id="HBK5434248.1"
                     /translation="MSRATEQEAYELLKKLGISFQKVDHPAITSVKNVPFSLPGPQVK
                     NLLLKSRKGKQIYLVILPDEKHADLKQLAEQLKEKRLSFVSEEQLPDLLGVPAGTVTP
                     LALMHDKEKKIQVVIDAAIDRQDTVGFHPNINTTTLIMDFSDFEKILVYLEHLPVYEN
                     L"
     misc_binding    3058..3403
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            3448..4089
                     /locus_tag="LLC22_000955"
     CDS             3448..4089
                     /locus_tag="LLC22_000955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5434249.1"
                     /translation="MEYLIEVMPQLLVGALTTLKLFLFTLIGSLPLGIVLALGLSLHF
                     KPLRYLLQTYVWVMRGTPLLLQLIFIFYGLPTIGIVFDRFEAALIAFILNYAAYFAEI
                     FRGGIQSIPQGQYEAAQVLQLSPFQTVTKIVIPQVTKIVLPSVGNEVINLVKDSSLIY
                     ILGLGDVMRAGKIAMERDATLLPLLGVAIIYLTLTGILTIVMKQVEGKLNYYR"
     gene            4108..4743
                     /locus_tag="LLC22_000956"
     CDS             4108..4743
                     /locus_tag="LLC22_000956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5434250.1"
                     /translation="MIELKKVNKAFGEKKIIKDLNLIIPDGKTLAIVGPSGGGKTTLL
                     RILAGLESSDSGEFYLDGVPFNPFELKMKEQVVGVVFQDFQLFPHLNIFENITLAPKM
                     VLKQTKEEYTKKAEELAASLGISDLLNIYPYQLSGGQKQRVAIARALAMNPRVLAYDE
                     PTSALDPELRQQVERLILSLKEDGVTQIIVTHDLVFAENVGDQLLKVSPIH"
     gene            4761..5576
                     /locus_tag="LLC22_000957"
     CDS             4761..5576
                     /locus_tag="LLC22_000957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5434251.1"
                     /translation="MKKTSFLFALIAGLLLFAGCSNKKTSADNWATINEEKKIVIGLD
                     DTFVPMGFRDKDGKLTGFDIDLAKAVFEQYGITVDFQPIDWSMKEFELNNGTIDLIWN
                     GYSKTPAREKKVQFTKPYMENDQVLITPKESGITNFGQMNNKRLGAQNGSSGYDVFTK
                     QPEVLKEIVKNQDAVLYDSFNEALIDLKSRRVDGLLMDKVYADYYLKQRNELEDFNIT
                     KGSYESEDFAVGARKSDSTLVKKINEALDQLEKTGEFQKISDKWFGEDVTPRN"
     gene            5895..7331
                     /locus_tag="LLC22_000958"
     CDS             5895..7331
                     /locus_tag="LLC22_000958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5434252.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            7520..9967
                     /locus_tag="LLC22_000959"
     CDS             7520..9967
                     /locus_tag="LLC22_000959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBK5434253.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            10197..11264
                     /gene="rlmN"
                     /locus_tag="LLC22_000960"
     CDS             10197..11264
                     /gene="rlmN"
                     /locus_tag="LLC22_000960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBK5434254.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(11457..12560)
                     /locus_tag="LLC22_000961"
     CDS             complement(11457..12560)
                     /locus_tag="LLC22_000961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBK5434255.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            13113..13661
                     /gene="aac(6')"
                     /locus_tag="LLC22_000962"
     CDS             13113..13661
                     /gene="aac(6')"
                     /locus_tag="LLC22_000962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBK5434256.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
     gene            14206..15867
                     /locus_tag="LLC22_000963"
     CDS             14206..15867
                     /locus_tag="LLC22_000963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5434257.1"
                     /translation="MKKKFTFGLVAVCGLVLAGCYGGSSATSSSSAKSGSADGGGVFN
                     LVVPQEMPTADLSVATDTISFTALNNVYEGIYRLDEDSKPQPAGASELAEVSEDGLTY
                     KIKLREDAKWSNGDPVTAADYVYGWQRTVDPATASEYAYLYAPVENAEDITAGKKDKS
                     ELGIKAVGDYELEIKLTKQTPYFQYLLAFPSFFPQKQSVVEENGDAYASASDKAVYNG
                     PFTLEDFDGPGTDTEWTYKKNDHYWDKDTVKLSEIKVSVVKESSTALNLFKDGQADDV
                     ILSGELAQQNANDPAYTSVKEARTSYIEFNQREKNSPFNNVNLRKAISYSIDREALVK
                     QVLGDGSVVSTGLIPSDMVKSPTTNEDFAKEAGKLVSYDKDKAKEYWEKAKKELGVDS
                     LEFDLMASDDDSSKKVIEYVQNSIQENLDGVTVKPTPVPFSVRLDRSTSGDFDAVLGG
                     WAADYADPSSFTDLFVTGNSYNRGRWSNAEYDEAVKAASSTDAGDEQARWDDFQKAIK
                     IISDDMGVVPVYQKAEGHLVNEKIKGIVHHAAGASWDYKWTYVEE"
     gene            complement(15937..16284)
                     /locus_tag="LLC22_000964"
     CDS             complement(15937..16284)
                     /locus_tag="LLC22_000964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3899 domain-containing protein"
                     /protein_id="HBK5434258.1"
                     /translation="MKKKSIPYAVAFLLILVILIKNLINHSFTLIQLSNDLFLWSLPF
                     LIIGGFLWVFSSGFFDHFQRSVHLARTRNRKKKPEFSSLSSASYGMYSFWLIIAGILI
                     ALSAIFMLFSLLG"
     gene            16368..17309
                     /locus_tag="LLC22_000965"
     CDS             16368..17309
                     /locus_tag="LLC22_000965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016184893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434259.1"
                     /translation="MNSYIKYVLKRVFFMIITLWLIATITFFLMQLLPGTPYTNQERL
                     SPETIEMLNKQVGLDKPVIVQYGIYLSNLLQGDFGISFQFKTQPVAHLLAGRIGPSLQ
                     LGLQAIIFGTVLGTILGTISAMKQNTWADTSSTLVAILGRSIPNFVFAVLLQYIFAIK
                     LQVLPIAKWDGFVYTILPTIALAMSPLADSARFIRTEMVEVLHSDYVELAKAKGLSRW
                     EIAFKHGLRNSLIPLMTLLGPLAVALMTGSLVVENIFAIPGIGEQFVKSITTNDYPTI
                     MAVTILYSFMLIFVILIVDLLYGLVDPRIRVSEGSRG"
     gene            17310..18353
                     /locus_tag="LLC22_000966"
     CDS             17310..18353
                     /locus_tag="LLC22_000966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434260.1"
                     /translation="MEMIPKRYETVADIPADEFLPLQKNTEEEREQITAPSLNFIQDS
                     WRRLKKNKAAVISMVLLLVIILISVITIFVSPHDPTAQNVAYINLPPRIPGINIDGLN
                     GKAMVGGELVDKYAQANVPSNVNFFLGTDGLGRDVLSRLFMGMRISLLIAFIAALLDV
                     TIGVAYGLVSGLLGGRVDNVMQRFLEILSGIPNLVVMILMLVVFEPGIFSIVAAMAIT
                     NWIPMARIVRAQTMKLKDQEYVLAGLTLGESRMKIAFKHILPNISSVIIIQMMFSIPS
                     AIFFEAFLSFIGLGLTPPSASLGTMLSEGYKTFLYLPYLLWIPAVTLSVIMIGFNLLA
                     DGLRDAFDPKMKE"
     gene            18359..19429
                     /locus_tag="LLC22_000967"
     CDS             18359..19429
                     /locus_tag="LLC22_000967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434261.1"
                     /translation="MTKILEVKDLEISFDTYAGKVRAIRGVNFHLNKGETLAIVGESG
                     SGKSVTTRSIMRLLSSNANIDAGQILFKGNDIVGKSEREMQKIRGKEIAMIFQDPMTS
                     LDPTMPIGKQVAESLRKHNKVSKKEGQKAALELLKLVGIPEAEKRINSYPHQFSGGQR
                     QRIVIAIALVCYPEILIADEPTTALDVTIQAQILELLKEIQTKIDTSIIFITHDLGVV
                     ANVADRVAVMYGGRIVEVGTSEEIFYNPQHPYTWGLLGSMPTLDSANDRLYAIPGSPP
                     DLLNPPKGDAFYPRNEFAMKIDAEQEPPFFELSKTHKAATWLLAPQAPKVTPPEEIQR
                     RWAIFKEKQKHTYGQGGIADAK"
     gene            19419..20372
                     /locus_tag="LLC22_000968"
     CDS             19419..20372
                     /locus_tag="LLC22_000968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5434262.1"
                     /translation="MPNKLLEVKGLKQYFNVGKKNEVHAVNDISFHIYEGETFGLVGE
                     SGSGKSTTGRTIIRLNEPTDGEILFDGQDITKIKDKKGLTKFRHDVQMIFQDPYASLN
                     PRMKVRDIIAEGIDVNGLAKSSEERAKKVDDLLRTVGLNPSHGTRYPHEFSGGQRQRI
                     GIARALAVKPRFIICDEPISALDVSIQAQVVNLLQDLQKEHQLTYLFIAHDLSMVKHI
                     SDRIGVMHNGLLLEMGTSDEIYNHGVHPYTESLLSAIPLPDPDHERKRRRIKYQPEPD
                     DGQVRQLREIAPEHFVYATEQEVPYYAKKLKRQKESLLVAN"
     gene            20384..21394
                     /locus_tag="LLC22_000969"
     CDS             20384..21394
                     /locus_tag="LLC22_000969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5434263.1"
                     /translation="MLKAFKFRMYPTEEQKQQLIRTFGCARFTYNHLLKKRQKSWQQT
                     GVANFSLTPATLKKEYPFLKEVDSLALANAQLNLDRAFRNYFKGRASFPKLKTKKSMW
                     QSYTTNNQTRTIYLENGYLKLPKQKELIKINQHRPVEGSIRSATISARYNEEFYVALL
                     CDVSPVKKESLAKWIGIAYHPKTLIQTSRPLEVTLPKFHQTEEKLQHAQRKLNVKVRS
                     AHHRKIRLDQASNYQKQKRKVMDLYLKQKNQREDYLEQLSGKLVKQYDYLFVESFPKE
                     EAHADFSIHDWHKLITKLRYKSQWYNKKFLLINTDGAEESNSVRKSQVVEKMGRHSVI
                     KG"
     gene            complement(21679..22500)
                     /locus_tag="LLC22_000970"
     CDS             complement(21679..22500)
                     /locus_tag="LLC22_000970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NUDIX hydrolase"
                     /protein_id="HBK5434264.1"
                     /translation="MNRFASKEEEKLYYEHKASEEEFLNWYQKQERPEYDKPSLTVDI
                     VLMCYNKEEDQLKVLLIQRKGHPYRNSWALPGGFVQKDESTGESVLRETKEETGVVIS
                     KENIEQLHTFSTPNRDPRGWVVTVSYLAFIGEEPLIAGDDAKEVRWFTLERHSNKIHL
                     SSGEVAISLDLVTGESSGKDTLAFDHSQIILKAFNRVVNKMEHEPQVLQVLGKDFTIT
                     EARKVFAKFLGIDYKTIDHSNFKKAMLQYFDEIGERPVGIGRPSKIYQLKPGHHE"
     gene            complement(22597..22875)
                     /locus_tag="LLC22_000971"
     CDS             complement(22597..22875)
                     /locus_tag="LLC22_000971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434265.1"
                     /translation="MQKKHLFFTLSIAFLSLAHLIFSYFYIRMYGYFNLHGHLNSFMT
                     AAWILRFIIDVYIVICGFFAIREERYKVLPFYLLFFLFNLILPFIFHI"
     gene            23143..25152
                     /gene="metG"
                     /locus_tag="LLC22_000972"
     CDS             23143..25152
                     /gene="metG"
                     /locus_tag="LLC22_000972"
                     /EC_number="6.1.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine--tRNA ligase"
                     /protein_id="HBK5434266.1"
                     /translation="MAEKETFYITTPIYYPSGKLHIGNSYTTIACDAIARYKRLMGFD
                     VFYLTGVDEHGQKIETKAEELGVKPQEYVDKMAADVKKLWKTLDISYDKFIRTTDDYH
                     KAAVQKIFDRLLEQGDIYLGEYEGWYSVSDEEFFTETQLAEVYKDDEGNVIGGKAPSG
                     HEVELVKEESYFFRMSKYADRLLEYYEEHPEFIQPESRKNEMINNFIKPGLEDLAVSR
                     TTFTWGVPVKSDPKHVVYVWIDALSNYITALGYGSEDESLFEKYWPADVQMVGKEIVR
                     FHTIYWPIMLMALDLPLPKKVFGHGWLLMKDGKMSKSKGNVVYPEMLVERYGLDALRY
                     YLLRAVPFGSDGVFTPEDFVSRVNYDLANDLGNLLNRTIAMINKYCDGLVPDYASLVT
                     PFDSELSTTAANVVGRYHDAMEKMEFNTALAEIWVLISRANKYIDETEPWVLAKDEEK
                     KAELNSVMIHLAESLRIAAILLQPIMTETPEKIFNQLGLDSETMNLEGLHFGEFPSGT
                     KVVAKGTPIFPRLDMEEEVAFIQEKMSEGTQTNEDTVKWDPEETELVSTKEKQIKFDV
                     FEKVELKVAEVINCQKVEGADKLLQFRLDAGDSQDRQILSGIAEFYPDPSELIGKKVV
                     IVANLKPRKMRGQISQGMILSAEAPDGSLQVIEAPKSMPNGSEIA"
     gene            complement(25631..26218)
                     /locus_tag="LLC22_000973"
     CDS             complement(25631..26218)
                     /locus_tag="LLC22_000973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434267.1"
                     /translation="MDFKRSYPKLADYLSNRVDFSRKEQQQSHWHWFTLILFGLMTVA
                     TLSQKLILLTLFIAIVALIKGPVMILWGMLYSFLVGLFPPIGILLSAIFFLLNIGTFT
                     KNWRMTLVGIYFYFYPFGVMALSEVMHWDNHWFIAGSLLLGLILLHVMLTKLYQHYGI
                     GRTIFWYVFSIPFALLTALLPSRLKTKIKGYHKIK"
     gene            26393..27715
                     /locus_tag="LLC22_000974"
     CDS             26393..27715
                     /locus_tag="LLC22_000974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5434268.1"
                     /translation="MKGKLKREINLFGALATVMGTVIGAGVFFKTAAVTASTQSTSLT
                     LLAWLLGGFLTICAGLTVAELATAIPETGGAVKYIEAAYGKLPSFLLGWAQSLIYFPA
                     NIAALSIIFATQLTNLLQLSTDYLLLIAVITAVSVTGLNLLGTKVGASVQSVTLIVKL
                     IPIAVIVIWGLLTPGQGTVQLFPIEAGKDVTFVEGLSSALLATLFAYDGWLGVGAMAG
                     EMKRPEKDLPKAIILGLSFVTVVYLLINFVFLKTLPIDHLAGNLNAASEASDVIFGGI
                     GGKLVTIGILISVYGALNGYTLTGIRVPYAMALEDELPFSKQLTKLSKKFTVPYVPAV
                     FQLAVACIMMSLGSFDFLTDMLIFVMWLFSLLIFIGVFILRKKAPELPRPYKVPLYPI
                     VPIIAILGAIFILGMTMMTQTKLALIGIGVTLIGIPVYYQKKKKRSEE"
     gene            27870..28646
                     /locus_tag="LLC22_000975"
     CDS             27870..28646
                     /locus_tag="LLC22_000975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBK5434269.1"
                     /translation="MIFDSHTHLNAEQFNEDIPETIQRAQEMGVTKMAVVGFDTPTIE
                     KSLQLSHDYPNIYSIIGWHPTEAGSYTKEIENKLQEQLTLPKVVALGEIGLDYHWMED
                     PKEVQDKVFRRQIAIAKEMNLPISIHTREALEDTYQILKEEDVRDIGGIMHSFSGDYE
                     WAKRFLDLGMHISFSGVVTFKKALDVQEAAANVPIERLLVETDAPYLAPVPFRGKRNE
                     PGYTRYTVEKIAELRNLPTEEVAAQTWTNAHRLFGLSEHG"
     gene            28639..29208
                     /gene="rnmV"
                     /locus_tag="LLC22_000976"
     CDS             28639..29208
                     /gene="rnmV"
                     /locus_tag="LLC22_000976"
                     /EC_number="3.1.26.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease M5"
                     /protein_id="HBK5434270.1"
                     /translation="MDKMKIQEIIVVEGKDDTRRLREVVDADTIETIGSAINEEILMQ
                     IEHAQETRGVIVFTDPDFSGEKIRKIIMEAVPQAKHAFLPRTQAKPKKKGSLGVEHAS
                     DAAILEALKKVVTPDISQTAVSEITRQDLLDYGLIAGAQAKEKREKLGDELRIGYTNG
                     KQLEKRLKMFRITPKELAQAMKIVEEQHE"
     gene            29201..30085
                     /gene="rsmA"
                     /locus_tag="LLC22_000977"
     CDS             29201..30085
                     /gene="rsmA"
                     /locus_tag="LLC22_000977"
                     /EC_number="2.1.1.182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (adenine(1518)-N(6)/adenine(1519)-N(6))-
                     dimethyltransferase RsmA"
                     /protein_id="HBK5434271.1"
                     /translation="MSEYREIATPSRTKEILLKHGFSFKKSLGQNFLTEPNILRKIVE
                     TAQIDEHTNVIEVGPGIGALTEQLAKHAKQVVAFEIDDRLIPVLADTMQPYDNVTIVH
                     QDILKTDLSTAVRETFHEELPLKVVANLPYYITTPIMMHFLESDLVVDELVVMMQKEV
                     ADRISAEPGTKAYGSLSIAVQYYMEASLAFIVPKTVFVPQPNVDSAILKLTRRDIPAV
                     EVTDEKAFFRLTKAAFQQRRKTLWNNLQHSYGKDDQTKAWLAKSLETAGIDPKRRGET
                     LSLQEFAALSNAMSENMQ"
     gene            30536..31165
                     /locus_tag="LLC22_000978"
     CDS             30536..31165
                     /locus_tag="LLC22_000978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434272.1"
                     /translation="MRKNSVRKLTISALLIGMGVIIPMVMPKIMIPPASFTLASHVPL
                     FIAMFFTPGVAVAVALGTTFGFFLTTPVIIALRALSHLVFALIGAWYLQKHPSIVLKN
                     GQFTFANWRFQGFNFVIGVIHSLAEMLVVSIFYFIGNMPETYYSQGYFYTVFILMGIG
                     GLIHSLVDYNIAYFIAGTLSKYFDIPVFTAAKKENRKESIQGYAKKTTY"
     gene            complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="LLC22_000979"
     CDS             complement(31289..32398)
                     /gene="ugpC"
                     /locus_tag="LLC22_000979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sn-glycerol-3-phosphate ABC transporter
                     ATP-binding protein UgpC"
                     /protein_id="HBK5434273.1"
                     /translation="MVEMALKNVYKKYDNAENYSVTDFNLSIKDREFIVFVGPSGCGK
                     STTLRMIAGLEDISEGELNIGGKVMNDVAPKDRDIAMVFQNYALYPHMTVFDNMAFGL
                     KLRKYDKADIKKRVDNAAEILGLTEYLKRKPAALSGGQRQRVALGRAIVRDAKVFLMD
                     EPLSNLDAKLRVAMRAEIAKLHQRLETTTIYVTHDQTEAMTMADRIVIMKDGFIQQIG
                     TPKEVYDTPVNMFVAGFIGSPAMNFFNVTLKNGVITDGHGLKLRIPEGKNKVLVEKGY
                     EGKEVIFGIRPEDIHSEQVALEASPEAVVKSEVVVSELLGAETMLYTKTGSTEFISKV
                     DARDFHKPGEIVDLAFNISKGHFFDKETEQVIKLP"
     gene            32607..33029
                     /gene="mgsA"
                     /locus_tag="LLC22_000980"
     CDS             32607..33029
                     /gene="mgsA"
                     /locus_tag="LLC22_000980"
                     /EC_number="4.2.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methylglyoxal synthase"
                     /protein_id="HBK5434274.1"
                     /translation="MKIALIAHDRKKPMMVKLATAYKTILEKHELFATGTTGQRITEA
                     TGLPIHRFKSGPLGGDQQIGAMISEDQLDLVIFLRDPLAAQPHEPDVTALIRLSDVYE
                     IPLATNIGTAEVLLRGLEAGFLDFRRIVHEIDKHPLSF"
     gene            33352..33888
                     /locus_tag="LLC22_000981"
     CDS             33352..33888
                     /locus_tag="LLC22_000981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBK5434275.1"
                     /translation="MKKHRLDARMIAIMGLLIALMVTLSRLVAIETPFIKISVTFIPQ
                     VIMGILFGPFWSGIGAVLADLVGMALFSKSAFFIGFTLNAFIEGAIYGFFFYRKEITW
                     KNAILATLSVTLIINLFLTPLWLALMYHVPLFSWVVWAPRLLKTVIWLPIQSIAIYYV
                     GRSIPYKKILRSLAIHAK"
     gene            complement(33928..35691)
                     /locus_tag="LLC22_000982"
     CDS             complement(33928..35691)
                     /locus_tag="LLC22_000982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434276.1"
                     /translation="MKVKKLSLQTLRRFIPYLTAYAKDIWLAVILGIINGIATVVMTL
                     QIGQSIDQMIGEGQVRFNRLFHLLILFGGIVLINVVSQWLIQVLSNRLAYLSVAKLRK
                     DAFAHLNRLPLRYYDQNSHGNIVSRFTNDMDNISIAISAAFNQLFSGVAIIILSFIFM
                     MRLSPLLTLVVLCSTPIIFLVSWIVARASQTNFDRQQRIIGDISGFVTERIGNQKIVK
                     AFQQEEASQQQFELLNADLYEKGQRAQFSSSLTNPSSRFVDHLAYLSIGLVGGLLALK
                     SGSSITVGVISSFTIYSSQFSKPFIELSGITTQLQTAFSGLERAFDLIDQPEEKPDLP
                     DAYALEPKNIKGKVSFDHVSFSYDPKQRLIEDFNFTAYPGQTIAIVGKTGAGKSTLVN
                     LLMRFYDTTKGTITVDDHDIRSIQRDTLRKSFGMVLQDTWLFDSTLRENLRFGNPEAS
                     DAEINDALKASYMYEFVERLPEKLDTKIGGQGLKISDGQRQLLTIARTMISNPPMLIL
                     DEATSSVDTLTEKKIQQAFLAMMEGKTSFVIAHRLSTIKNADQILVMDQGAIVEMGTH
                     DELLQKDGYYRRLYQAQFTAQ"
     gene            complement(35694..37409)
                     /locus_tag="LLC22_000983"
     CDS             complement(35694..37409)
                     /locus_tag="LLC22_000983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434277.1"
                     /translation="MIQLLRYAKDYRKQIILGPFFKFLEAVFELVLPLMMASLIDNGL
                     KMNDRGKIIEMGLWMVAMSVIGLICAIICQYYASVASQGFGTELRNQLIKKINTFSHN
                     ELNHFGTDTLITRMTNDINQLQLALAMVIRLLIRAPFLSIGSVVMAFVIDWEVGLFFL
                     ALLPIFSIILFFIIKKTVPLYQKVQEKLDQLNEHVSQNLSGVRVIRAFAQTKKETEKF
                     DKSTNDLANNYLRVSNISALLSPATTLIMNVGIICLLTVGGIKVNIGSLQQGQVLALI
                     NYMNQMLLALIVVSNLVVIFTRAEASGNRVKEVLDTENSILEAEVSTTPDFSSEAIIA
                     FDHVDFRYTPDSGLSLQNITFQLKRNTVLGIIGPTGSGKTTLTQLIPRFYDVSSGTVI
                     MDGMDVRSWQLDHLRQQIALVPQTSVLFTGTIRENLQWGKKDATEKECWEALKIAQAE
                     EFVRQLPNGLDTKVMENGKNFSGGQKQRLTIARALIAKPALLILDDSLSALDYQTDLD
                     LRKALQTYLGSTVIIISQRVRSIQEAHHILVMDQGKIAAQGTHEELLAQSAEYQEIVA
                     SQEEE"
     gene            complement(38188..38412)
                     /locus_tag="LLC22_000984"
     CDS             complement(38188..38412)
                     /locus_tag="LLC22_000984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434278.1"
                     /translation="MKSDKYKNRKHTSWKTFREIIGSYLAVVVFLPLLYMAMTEQTRF
                     IGVDTQYIAETGFLFIFILIFAFYKSFHTK"
     gene            38603..41380
                     /locus_tag="LLC22_000985"
     CDS             38603..41380
                     /locus_tag="LLC22_000985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5434279.1"
                     /translation="MNKLLKKEILCYLENQTAFFDLEHMNEVFTAQRLADHFGVKRNT
                     VSHYLNQLNDEQLLVKINSRPVIYFHKEAFEKQFFKLRTNFYFSIDDLKEEQPFFAQP
                     KDLFSFMIGYDASLKESIEQIKTALYYPDGGLPLLITGESGTGKSYLVNLVYQYCLLH
                     DLLEDSAPFITFNCAQYADNPELLTSNLFGHVKGAYTGAEENKKGAFEAADGGILFLD
                     EVHRLTPEGQEKLFTYLDQGVIYRMGEPNLSRRIKTRLFFATTEEITSHFLTTFIRRI
                     PIRIELPALNQRSRNERLELIYSFFLEEQRKMGSPLSVSGPALSLLTSQKLSGNIGEL
                     KNIVKVSAAKAYAEQREQPEIHVTIHHLQKELLAQPITKNTAQQGIYITQDQTLEQLM
                     EKQQPEQQRIVKSFEQILIDFKKNNCLLYSCEGKLKQEVIQLFDFLLFETSRQEKHEL
                     LVYWTQSIRETFRQMETAYQIKFDGNSVYALSYYLYQRSTIKWLPEEHDIIQLIKELE
                     QQVSQSYPSSYHYVQRILELSKIKLDIEDTSMDRILLTIYLKKAKWSKEKRLPKAMIA
                     AHGYATASSMANVVNRLLQEDLFESFDMPLDVTPQQIASEILDYCENSDVSNGLIILV
                     DMGSLKEIHQFFKKQLSVPLLILNNVTTPLAITVGECLQKNVSLEEIAEETVRQIQPE
                     WRLLYPEENKPKALITTCFTGIGTAVHLSELLEKSLPTACQLKIIPYEYQQLKDKKNS
                     DPLFSIYEVVGMIGTTDPDITNIDYLSLEDLISGEKMSVLAEWLDTTMNASEKEIFNQ
                     RIIRNFSLEKVLDSVTILDTEKVMGEIDHFMRELEVQLNRSISNPKKLALYVHVSCLI
                     ERLIRQMPIETYQGLEKWKQCQKEGLSAIKSAFSVIEEHYSVMIPNSEIAYIYDILSE
                     DTEFLSIEEEF"
     gene            41461..41880
                     /locus_tag="LLC22_000986"
     CDS             41461..41880
                     /locus_tag="LLC22_000986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannose transporter subunit IIA"
                     /protein_id="HBK5434280.1"
                     /translation="MDREIILASHGKFASGILDSLELIYGKNHSITVFDCYTDENFDL
                     AETVRQLFMRYKDKEIIVLTDLFGGSVNNEFLQYINRDHVYLVAGLNLPLLIELVSRL
                     DAEVETTVLIQQVLTDSKKMIQFCNERLNQKIEEDEF"
     gene            41892..42362
                     /locus_tag="LLC22_000987"
     CDS             41892..42362
                     /locus_tag="LLC22_000987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5434281.1"
                     /translation="MIVLTRVDHRLLHGQVAFSWTQTIGADCILIANDDVPTNEIRKT
                     TIKLAKPQGVKLVIKSIDDSIAALKSGVTDKYKLFIVVESIEDAYKLAEAYPEIKTIN
                     LGGIKAKPGTRSIGKAVNILPEEEERLKRLIDKQIEVEIRQVPADKKVDVREVL"
     gene            42379..43158
                     /locus_tag="LLC22_000988"
     CDS             42379..43158
                     /locus_tag="LLC22_000988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5434282.1"
                     /translation="MIVQAVLLGIVAFVAQSEYALGTSLLSRPIVTGLFTGIVLGDVK
                     TGIIMGATLELAFIGSFSVGASIPPDVVTGGILGTAFAITAGAGTETALLLGLPIATL
                     TLILKNIYLGLLIPIMNHKADNYAEEGNYKGVEHMHLLAGIGLSLMLGVVVMVSYMVG
                     SNTIGNLLNMIPDFVQKGLSVATGLIPALGFAMLARLLINKQVAPYFFLGFAIASYLE
                     IPVTGVAIFGAILAVVVVNIMNVRQLPLQTTAGEVEEDEEF"
     gene            43145..43966
                     /locus_tag="LLC22_000989"
     CDS             43145..43966
                     /locus_tag="LLC22_000989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375593.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5434283.1"
                     /translation="MKNSEIKNSKITKKELNHVFWRSFQMEFSWNYERQMNMAYVYAM
                     IPILKKLYQSKEEMAAALKRHLEFFNTTPHIVTLILGITAAMEEENKDDPEFDVTAID
                     SIKTSLMGPLAGLGDSFFWGTLRLIATGVGTSLAMQGNILGPILFILIFNIPHILFRY
                     LATGWGYRLGTGFLKKIQANGMMESLTLGASIIGLMVVGAMTATMITINIPLKIGSGE
                     NAVTVQSIFDDIVPNILCLGAFGIVFYLLKKEVKPLTILIGLAFFGIFGSWIGIF"
     gene            43983..45032
                     /locus_tag="LLC22_000990"
     CDS             43983..45032
                     /locus_tag="LLC22_000990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287118.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5434284.1"
                     /translation="MFTMQDYIYEEKEVLSTILKKNDFSTREHMKKTVNLLILATGSS
                     YNACLAAKPALESYGDLTVDIQEPFYFFNYGKLSPSIDTVIAVSQSGKSASTVEAVKM
                     IQKQGLPVVAITNDVQSPLALEAAQIIDLGAGVESVGFVTKGYSATVLQLLLLGIGIG
                     ISKNKISKKIEQDYMQQLRKIINHLPAIIQKTEEFFDGYQSLFRLAQRFVTIGYGPNW
                     GTAKEAETKLTETIRVPSQGFELEAYMHGPYLEADASHLLFFIEGESVNKERSQKLQR
                     YMSRYVGETLTITTKKARNEKTLGLAIECDEYLSVLALVVPFQLFAYKTAVAKGIDLN
                     KKIFEDFDTVLKSKL"
     gene            45045..46049
                     /locus_tag="LLC22_000991"
     CDS             45045..46049
                     /locus_tag="LLC22_000991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344006.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5434285.1"
                     /translation="MLKFNEEEQIKAIKGALALRPQVEEIIDKLYAEKFDAVYYLGIG
                     GTYASSMQAVTYMNGKSNLPVFVQHAAEYYTTGNKRLTKDSIVILSSVTGTTQEVVKA
                     VEQIKKVGATLIGFIDKANSKLSQLCDFVVTYPAPGTEQIKFFMAADRLMYLNGEFEA
                     YSEYYEQLERYLPTGLVEAEKKADAFGLSFAEKHRRDSMHYFIGAGNQWGAVYSYAMC
                     YWEEQSWLPSKSIHAAEFLHGTLEIVEETTPVTLFLGEDEQRVLSERVAKLLPKICSN
                     YTLIDTKDYPVEGISEKYRGRVLSFLLMHVVTQRIDAHVEQLNCHPLEIRRYYRQFDY
                     "
BASE COUNT        15257 a         8049 c         9519 g        13327 t
ORIGIN      
        1 atatagtagg ttttattttt agttaaaata ggggagatag aaaaaatgaa aaagtgtaga
       61 aatattattt tatcaatgtt atttattatt actaatataa catcactgat tcctgttcat
      121 gtctatgcgg atgcaggcag agatatcagc agtaatgtca cttcgttgac cgtggaccca
      181 acgaatatta cagatggagg aaacataaaa gtaaaattct cgtttgacga aaaaaaacaa
      241 aatatccaac caggtgatta tctttggatc aattggccaa gtgaaggaaa tattcgcggt
      301 gaaggattcc aaaaagaaat cccattaatg attgaaaata aaaatgttgg aactttaacg
      361 gtcagaaaag attctgcgca ggttgtgttt aatgaaaata ttaaaaacct agactcagta
      421 gaaggttggg ggcaatttga gatacaggcc agaaacgtaa ccgataccgg tgaagaaaat
      481 acgggaccat tcaccgtgac gagcggtgat aaaacagcta ctgtaaatgt gacaaagcca
      541 gcttctggtt cttcttctag cgttttttat tataaaacag gagacatgct acctgaagat
      601 actaagcaca ttcgatggtt tttgaatatt aacaataacg gcacttatgt tgaacaacca
      661 gttaaaatca gtgatgaaat ccaaagtgga caaagattag atccaagtac gtttgaaatt
      721 aatcaaatac acttaggtga acagaaggtt tatagaggag aagagggaat ccaacaattt
      781 ttacaagatt tccccagcgc tacatttaat ttttcagtaa ctgataatta cattgaaata
      841 actataccaa aaaactttgt caatcttagg aaaataatgg tgagttataa gacgatcata
      901 gaaaacccag aacaaataaa ttttgagaat cattcggaag cttggtttaa agaatttaat
      961 aaacctgctg ttgatggaga aagtttcaat catacagtta aaaatatttc agcttctggt
     1021 ggagtcaacg gtacagttag aggcgaattg aagattttca aatatatcaa tgacacagag
     1081 attggtatcc caaatgtgac tttcgaatta agacgagcag atgaacagcc tattcaagga
     1141 cagtctagta tcctgttgac ttcgaatgaa cagggagaag ctagtatcaa aggcctgcaa
     1201 gtaggagact atgttgtaaa agaaaaagaa gcacccaatt ggattgattt tgatccacta
     1261 agttcaaatg aactcaaatt ctccataaac gaaaatgata cagagggagt cagtttacct
     1321 atttataaca agaaaaaggt tacgaacatc acagcaacta aaatttggaa cggtggaacc
     1381 actccaagac cgagtattta ttttaaatta ttcagagcaa gtacaaacaa ttgggaacca
     1441 gttcctgatg cagaaacaaa acgattagac aatggaataa cttcagtgac ttgggaagat
     1501 atccaacagt atgatgatag tggaaacgaa tatacgttta aagtgcaaga agtagatcaa
     1561 aacggaaatg attatgtccc ttcaggttat caaaaaattg aaaacgggct agtcgttaca
     1621 aatgagaata aagaagtcat ttcagtctca ggacaaaaaa catgggaaga caatgagaac
     1681 caagacggca aacgaccgac gacgatcaca gtaaatctat tagccgacgg tcaaccgatc
     1741 caacacaaag aagtaagtga aaaagatgat tggcgctatc gtttcacaaa tctgccaaaa
     1801 tacagagacg ggcaagaaat catctatact gtaacggaag acaacgtgcc cgaatacagt
     1861 acgacgattg acgggtataa catcaaaaac agttatacac cggaaaaaac aaatatatct
     1921 ataccaggta gccatataac accgtggaaa aattttccag agaagacaga gagagagaaa
     1981 attagaaatc tattctctca aaaattgcaa atatttgctc atacaggaga atccagcgaa
     2041 caaagaagca attatattag taagagagct gtacctaaac agataacaaa taaatcaaaa
     2101 agcattcttc ctaaaacaag tagtaaaaaa tctagttttg ctgtaatcat tggtttattg
     2161 atagtaacta tctgtgctgg gatattctta caaaaatata aaaaagttta gttagaatat
     2221 aatatttttt gttaaatatg actgaaatca aaagaataaa attccgattt ataatcgaaa
     2281 aaagaagcat ttttatatat gcttcttttt tcgtagaatc aataaatatg gatttggcta
     2341 actatggaag aatactcgta ttagttttca gcgttcatac tagttgttac attgtttgat
     2401 tggccaaaag aatttctgat atattttgtg ctaaataaag aaaaagacgc ttgaattggg
     2461 aaataagaaa actactctat cattacaaat tttcataaac tggcagatgt tctaagtaaa
     2521 caagtatctt ttcaaagtcg gaaaaatcca taatcaacgt agtggtattg atatttggat
     2581 gaaagcctac ggtatcttga cgatcaatag cagcatcgat cacgacttgg atttttttct
     2641 ctttgtcgtg catcaatgct aatggagtca ctgtacctgc tggaacgcct aggaggtcag
     2701 gaagctgttc ttcagaaaca aaagataagc gcttttcttt taattgttca gctagttgtt
     2761 ttaaatcggc gtgcttttca tcaggcaaga tgacaagata gatttgtttt ccttttcttg
     2821 atttcaataa tagatttttt acttgcggac caggtaggga aaaagggaca tttttgactg
     2881 acgtaatcgc aggatgatcg actttttgaa aagagatacc cagttttttt agtagttcat
     2941 aagcttcttg ttcggttgca cgactcatcg cgcatcaccc tccttttttt attagtgtat
     3001 cataaaaaag agttgacaaa tgaaaaataa tcatgtaaat tacacgtaaa gttaaaacaa
     3061 atgacatcga aaagaagagt agccgttagg tgtttttaga gagtctctgg ttggtggaaa
     3121 gaggcagcag ttaaccgtga aacacatctt ggagtcgatt ttctgaagcg tatagtagga
     3181 aaatccgggg agcccgttac agctgcggtc gttgctagat gaccagataa ggctggcttt
     3241 tccgtgagga gtcggtaaaa aaaggtggaa ccacgtgatt aacgtccttt gatcttcgga
     3301 tcaaaggact ttttgttttc atctgaacgg caacgactgt gtgaggtttt ttctgcaagg
     3361 aaaaaataaa cagaggtgga accacgtata atacgtcctc ttggcatttg ccaagaggat
     3421 ttttttattt taaaggagga aaagaagatg gagtatttga ttgaagttat gccgcaatta
     3481 ttagtaggag cactcacaac attgaaatta tttttattta ccttgattgg ctcattacca
     3541 ttagggattg ttttagcatt aggattgtct ttgcatttta agccgctacg ctacttgctt
     3601 caaacatatg tatgggttat gcggggaaca ccgctgttgt tgcaactgat ttttattttt
     3661 tatgggttgc cgacgattgg gatcgttttt gatcgtttcg aagcagcact cattgccttt
     3721 atcttaaact atgcagctta ttttgcagag atctttcgtg gagggataca atcgattcct
     3781 caaggtcaat atgaagcagc gcaagttttg caattaagtc cctttcaaac ggtgacgaaa
     3841 atcgtcatcc cacaagtgac aaagattgtt ttaccttctg tagggaatga agttatcaac
     3901 ttggtcaaag attcttcctt gatctatata ttaggtttag gtgacgtaat gcgtgctggg
     3961 aaaatcgcga tggaacgcga cgcgacttta ctgcctttgc taggcgtggc aatcatctat
     4021 cttacattga ctggtattct aacaatcgta atgaaacaag ttgaaggaaa attaaattat
     4081 taccgctaac tgataggagg aagaaatatg attgaattga agaaagtgaa caaagcattt
     4141 ggtgaaaaaa aaataatcaa agatttgaat ctaatcattc cagatgggaa aacattagct
     4201 atcgtaggtc cttccggtgg cggtaaaacc acgcttttac gtatcttggc tggcttagaa
     4261 agttctgaca gcggagaatt ttatttagac ggtgtaccgt tcaacccatt cgagcttaaa
     4321 atgaaagaac aagttgtagg agtcgtattc caagacttcc agctatttcc acatctgaat
     4381 atttttgaaa acattacctt agcaccaaaa atggtattga aacagacaaa agaagaatac
     4441 accaaaaaag cagaagaatt agcggcttca ttagggatta gtgatttatt gaatatctat
     4501 ccttatcagc tttctggcgg acaaaaacag cgggtagcga ttgccagagc attggctatg
     4561 aatccacggg tattggctta tgatgaacca acaagtgctt tagatcctga attacgccag
     4621 caagtcgagc gtttgatcct atcattgaaa gaagatgggg taacccaaat tattgtcacc
     4681 catgatttag tatttgcaga aaatgtcggt gatcaattac taaaagtttc cccaattcat
     4741 taagaaagga gaagatagag atgaaaaaaa ccagttttct attcgctttg atcgcaggtc
     4801 ttcttctttt tgcaggctgt tcgaacaaaa aaacttcagc agataattgg gcgactatca
     4861 acgaagagaa aaaaatcgtt ataggtttag acgatacatt tgttcctatg ggatttagag
     4921 ataaagacgg gaagctcaca ggatttgata ttgatttagc caaagcagtc tttgaacaat
     4981 atgggattac ggtagacttt cagcccattg actggtcaat gaaggaattt gaactgaaca
     5041 atggaacgat cgatttgata tggaacggct attccaaaac gccggcaaga gaaaagaaag
     5101 tgcaatttac aaaaccttat atggaaaacg atcaagtgct gatcacacct aaagaatcag
     5161 gaatcacaaa ctttggacaa atgaataata agagattagg tgcgcaaaat gggtcatctg
     5221 gttatgatgt atttacgaaa caaccagaag tattaaaaga gatagtcaaa aaccaagatg
     5281 ctgttttgta tgatagtttt aatgaagcat tgatcgatct gaaaagcaga cgggtcgatg
     5341 gtctgctgat ggataaagta tacgcagact attatttgaa acaaagaaac gaactagaag
     5401 acttcaacat aacaaaaggt tcttatgaga gtgaggattt tgcagttggt gcacgcaagt
     5461 cagatagtac attagtgaaa aaaatcaatg aagccctaga tcaactagag aaaacaggtg
     5521 aattccaaaa aatatccgat aaatggtttg gcgaagatgt tacgccgaga aattaacaaa
     5581 taggggactg tgacaaaaga cgtgtcacag tccctttttc cgaataaaca gtgttctcct
     5641 gccaactcct tgtgactcgg agctgaatgg caggctcaca acctcttggt aaacggtgtt
     5701 caaaagccag tttttcggta ttaagccaaa tttatgcaaa aatgtagaaa gccattttca
     5761 caaaattttt cttactactc gaaactaagc gactttttca caacctcctt tacatatttt
     5821 tattttgttg tggaaggggt ttcgtgttat tctaaaagag gaacgattga aggttatagg
     5881 aaaggaagag atgaatggaa cacaaagaac ttacctcatt tccaaaagat tttctgtggg
     5941 gctctgcttc tgcagcgtat caagtagaag gagcttggca agaagatggg aaaggagaat
     6001 cagtctggga tcgatttgta cggatacctg gaaagacatt taaaggaacg aacggtgatt
     6061 tggcagtaga ccactatcat cgttataaag aagatattgc tttaatgaaa gaacaaggtc
     6121 tgaaagctta ccgcttctct gtagcttgga cacggatttt tcctaatgga cgaggagaag
     6181 tcaatcaagc tgggctcgct ttttatgaga gattgatcga cgaattgatt gaaaacgata
     6241 ttgaacctat gttgacttta tatcattggg atcttccaca agcattgcaa gatgaatata
     6301 atggttggga atcacgtcag atcattgaag atttcactca ttatgcagaa acattatttg
     6361 aggcattccg cgggaaagtc cattactgga ttagtttgaa tgaacaaaat atcttcactt
     6421 cattaggtta tttgttagca gcacatccgc caggtgtgac agacccgaaa cgaatgtatg
     6481 aagttaacca tattgctaat ttagcaaatg catctgtcat caataaattt cacgagttag
     6541 aaatgcctgg aaaaatcgga ccaagctttg cgtatacgcc aaattatcca attgacagta
     6601 atcctgaaaa tgttctggct gctgaaaatg cagaagacct gatggccaat tattggatgg
     6661 atgtctatat gtggggaaaa tatccgattg ctgccatgag gttcttagaa gaaaaaggat
     6721 gggcaccaac gattgaagct ggcgatgcag aattgctaga atctgctaaa ccagattttc
     6781 ttgggatcaa ttactatcaa acggcgacga atgcattcaa tccattaaac ggagttggtg
     6841 ctggaaaaat gaatacgaca ggaaaaaaag gttcatcaga agaaactgga gttcctggaa
     6901 tgtataaaaa agttgagaat ccatttgtcg aacgaacaaa ttgggactgg gagattgacc
     6961 cagaaggatt aaggatcgga ctgcgtcgta tcacaagccg ttaccgcatg ccggtactga
     7021 ttacggaaaa tggcttagga gagtatgaca agttgacaga agataaacaa atccatgacg
     7081 actatcgaat caattactta caaagccacg tcaaagccat caaagaagca atttcggatg
     7141 gagcagaagt cctaggctat tgcacctggt cttatacaga tttgcttagc tggctgaacg
     7201 gttatcaaaa gcgatatgga tttgtatatg ttgatcaaga cgaaacacaa gaaggatctt
     7261 tggaacgata taagaaagac agttattact ggtaccaaaa actgattgaa gaaaatggag
     7321 agaaccttta gttcacatac ttaaaacaag aaggtacggc tggatatggc cgtgcctttt
     7381 cttgataaaa tcatttagaa attaagaaaa actgtaaaat aagctgaaaa atgaaagaaa
     7441 gcgtcagttc tttcaaacaa aactttagtt cccttacttt tttttgtata atgaaacttg
     7501 atgaaatgag ggataataaa tggcacaaaa gaaacggcct actaaaaaaa ggaaaaagac
     7561 gaaaaaaacg aaaaagcaaa aacagcagca ggaacaaatg ctgacgattg gtgttgggtt
     7621 tgccttgatt ttatttgctg tcttcggctt tttaaaatta ggttttttag gaatattgat
     7681 tgcaaacggc tttcggatca ttgcaggaaa tacttaccaa atcctctgtc ttttattagc
     7741 cgtattagga ttttggattg tcattaagaa tacagagttt tcaattggta aaaaccgacg
     7801 ctggtttggc ggcatactct tttatttcgg tatcttatta ttgttacatg cccatttatt
     7861 tggcaaactc catactgggg aaccaaatat catggggacg acatgggatt tgttagccag
     7921 tgatataaaa caaagtcaag tagacaataa cgttggtggt gggatgattg gagcaatcct
     7981 ttatcatttt acttacttct tgattgcaca gcctggaagt tatttagcag cagtgctatt
     8041 actggcagga ggagcattcc tgttcagtaa tctggaaggc tatcagctgt taaatggtat
     8101 ccaatcaatt ggagaacgag tacaggaatt attggaaggt gatcctgcca agcaagctcg
     8161 aaagcaagcg gcaaaggaag agagaatgaa acagcgcgca gaagcgaaag aagcaaggcg
     8221 cttagctgca aaagaagctg cagaaaaaga agctgcagaa tatgagaaga aaaaagcggt
     8281 gagccagcaa agggaaaata ctgctgatga atggcaggaa ccagaaaata cagagccgga
     8341 gcagctaagt tttgttccaa tcgacagttt tcaagaaaat atccatcctg cgaatctaga
     8401 gaaaccagta ccagatacac caaaacagac caatacagca gaaggttttt cagatgagtt
     8461 gccagaggat gacggtacct cattagaatt tgagattgaa gcagaacagg aaaatcaaga
     8521 ctatgaatta ccgacagttg atttgcttga ttctatacca actgtggatc aaagtgatga
     8581 gtataaaaaa attgaaaaaa atatcggcgt attagaacaa actttccaaa gtttcggtgt
     8641 cgatgccaag gtcgtcaaag ccagcttagg accatccgtc acaaaattcg aagtccagcc
     8701 ggctgtaggg gtaaaagtaa gtaaaattgt gaacttaaca gatgatatcg cgcttgcttt
     8761 agcggcgaaa gatgtccgga tggaagcacc gattccaggt aaatcactga ttggtattga
     8821 agtaccaaat ggaaagatca gtatggtttc ctttagagaa atcatcgaag cacaaccaaa
     8881 ccacccagat aaattactag aagtaccttt aggacgtgat gtttctggac gggtacaaac
     8941 ggctgatctt tcgaagatgc ctcacttact cgtggctggt tcgactggta gtgggaagtc
     9001 agtagcaatt aatgggatta tcacaagtat attaatgcgt gctaagcccc atgaagtaaa
     9061 actgatgatg atcgatccga aaatggttga attgaatatg tacaacggca tacctcatct
     9121 gttgacgccg gtcgtgacga accctagaaa agcagcgcaa gccttacaaa aagtagtaca
     9181 agaaatggaa gaacgatatg aaaaattcgc ggcaaccgga gtaagaaata tttctggtta
     9241 caatgaattt gttcaacaga aaaacttgga aaacggaacg aaacatccaa ccttaccatt
     9301 catcgtagtg atcgtagatg aattagctga tttgatgatg gtagccagca atgaagttga
     9361 agatgcgatt attcgtttag cgcaaatggc tcgggcagcg gggattcata tgatcctagc
     9421 tactcaacgt ccaagtgtgg atgttatcac aggaatcatc aaagcaaatg taccttccag
     9481 aatggcattt gcggtatcaa gcggtacaga ttctcggacg atcattgatt ctaatggggc
     9541 agaaaagctc ttagggcgag gagatatgct attcttgcca atgggtgaga ataaaccgat
     9601 ccgtgtgcaa ggagcattca tttctgacca cgaagtagaa cgggtcgttc aatttgttac
     9661 agatcagcaa gaagctcatt atgaagagaa aatgatgccg acagatgaag ttgaaacgac
     9721 aggtgctcca gaacagccac aagatgagct gtttgaagaa gcaaaagcac ttgtcgttga
     9781 aatgcaaacg gcaagtattt cccttctcca aagaagattt cggatcggtt acaaccgagc
     9841 agcacgttta gtagatgaac tggaagctca tggagttgtt ggcccgtcag aaggaagcaa
     9901 gcctcggaaa gtattcattg agcaggaaga aacatcagaa acgttgccgg acgataatga
     9961 catgtaaaac ttgtgtgatg aagggttgaa aaacgaataa ccaataaaaa gacaaggcat
    10021 gatgatacca aaagaaaaaa tggttttttt ccatcttttc taatacggta tgatgtcttg
    10081 tctttttagt ttttgtgaga ttaaagttct attcgattta tttgtgaagt attgcattaa
    10141 ggaaatgaat catgtatagt atgtagcgaa actttgagaa aaagagggaa aatactttgg
    10201 aaaaacagtc catttatggc ttgacgaatg aagaattaat caattggttt atagaaaacg
    10261 gcgagaaaaa attccgagct gcccaagttt gggaatggtt gtatcaaaaa cgtgtaagta
    10321 atttcacaga aatgacgaat ctatcgaaac aattgatcga aaaattatcg gagcatttta
    10381 tcatcaatcc tctaaaacag atggtcgtcc aagaagcttc ggatggtaca gtaaaatatt
    10441 tgtttgaact ccctgataaa aacatgattg agactgtact gatgagacaa gaatatggct
    10501 tgtcagtttg tgtgacgaca caagtaggat gtaatatcgg ctgtacgttt tgtgcaagcg
    10561 ggctgctcaa aaagaaccgt gatctgactg ctggagaaat tgttgcacag atcatgatgg
    10621 tccaacatta ttttgatgag cgcaatcttg gcgaacgcgt ttcacatgtc gttgtaatgg
    10681 ggatcggtga gccatttgat aattacgaca atgtaatgga ctttttgcat atcatcaatg
    10741 atgccaaagg attggcaatt ggtgctcggc acattacagt ttccactagt ggattagcac
    10801 acaaaatcaa ggaattcgct aataacggct tgcaagtcaa tctggctatt tccttgcacg
    10861 cgccgaataa tgaggtgcga acatcgatca tgcggatcaa ccgaagtttc ccaattgaga
    10921 aattgatgga agctgtggat gagtatttag agaaaacaaa ccgtcgaatc acgtttgaat
    10981 atatcatgtt gaatcaagta aatgatagac cagagcatgc gcaacaatta gcagatctat
    11041 taaaagataa gaaaaaatta gcatatgtca acttgattcc atataatcca gtcagtgaac
    11101 atgatcaata ttctcgcagt ccaaaagctg atgtattgag attttatgat gtattgaaga
    11161 aaaacggcgt aaactgtgtg atacgtaaag aacatggtac agatattgat gcagcttgcg
    11221 gacaattgcg aagcaagcaa atgaaaaaaa cagttgccaa ataatcgtat cctactcgtt
    11281 ttttcaatta ccataaaagg agcagttttc ttaattaagg aactgttcaa cttaaataag
    11341 agaaaagatt ctatagcgaa agctataaag ctttttttga caagaaaaac cctcatcaag
    11401 caaagaaatg tcctcaattt gatgacagcc tgcttgatgg gggttttagc aattatttaa
    11461 ctgattttct tatatccttg ctggctttct tgtgtagcat gataagtttc tacgtcaaga
    11521 atggcctgtt taaatttttc tcgggtgatt tcataaggca catgtttaat atcatttgtt
    11581 gccatggctt tatctaagat tgcttctaaa tcggtcgtga cattgagatt catgtcggtt
    11641 aacgatactg gaagttggtt ctttttcata aacacataga ttttatcaaa caaatcgaac
    11701 tgctgatcca tcatcaataa ggtcagtaca ccataactga cagatgctcc gtgaaggtat
    11761 ccctccattt tttctagaac agtcgtaccg taatagaatg agtgtgccat agcagaatta
    11821 tagttattgt taactaaaac agaaaccaat ccggtagtaa caatgatatc cgaaacgact
    11881 tgttcaattg catatgaggg acgatcgtcg gcactatctt tcaatgcttg cgtaccataa
    11941 gtcaagagac gatcaatgca catttttccg atttggattc ctaatctatc cgtgtagcct
    12001 agatcatcgc cacgagcaga aaaagtagat tcgacttctt tggataaagc atcgccaata
    12061 cctgcccata agtatttatc aggtgcttcg gcaataattg ctgtatcaat gaaggtgtgt
    12121 acaggtggtt ttgaaggaaa gaagagtccg tccattacgc cttcttcgtt atagatgaca
    12181 cataccgcag tgacgggcga acagttcgaa ccaatagtgg gaaaggtgaa gactggttta
    12241 gctagttttt caccaatgac ttttacagta tcgcaagcac ggccaccacc gactgcaaac
    12301 aggacgtctg ctttttggac actttcatgc tggatcaact gttcaatatt tccataagtt
    12361 gaattacccc cgtaccagag actggcgaca acctctattt cctgtgtcaa agctactttt
    12421 attttgtttt ctgcctttga aagtgcagtc ttccctccaa tcagcactac ttttgtccca
    12481 tattctttga cgattccatt tgctttttca tacgcatctg ttccaatggt ataatttggt
    12541 aagaaaacac tttgactcat attcatttcc ttctttcttc gttgaaacgg gttaaaattt
    12601 taaagagtga tcgatctgac tgcggctgta gatggagtag aggtgaacct aagacaggat
    12661 aagtgatgaa taaggtggca tgaacacctt gaaatcatca ataagtatcc taaaaacgaa
    12721 caagtacaaa aacattgaaa acgacaataa tgaatttttg ttcctcttag tatttctacc
    12781 gattcccttt gcttttttgt aattatctaa aaattctaaa aattaagatt attatatgaa
    12841 aacaggtttt atttgtcaat tcataattgg ttttttttaa agcaaaagat aatctatatc
    12901 atgatgaaca aacagagttt tttcctccaa ttgatggctt tcctgatctt tcctattttg
    12961 aataaagtgt ttctgtataa tttttttatt ttataagtaa gataaataat gaaagaatag
    13021 agatactgat tggtagctaa agatttttga gcgagaacat ttcgtttttt caaaaggact
    13081 gttagaataa gcaagaacaa gggggaagac gtatgataat cagtgaattt gaccgtaata
    13141 atccagtatt gaaagatcag ctttctgatt tactgagact gacttggccg gaagaatatg
    13201 gagacagctc ggcagaagaa gtagaagaaa tgatgaatcc agaacgaatc gcggtagcag
    13261 cggtagacca agatgagtta gtaggattta ttggtgcaat ccctcaatac ggtatcacag
    13321 gttgggaatt gcatccatta gttgtagaaa gctcccgacg aaagaaccaa ataggtactc
    13381 gattagtcaa ttacttagaa aaagaagtag cttccagagg aggaatcacg atttatttag
    13441 gtacggatga tttagaccat ggaacaacgt taagtcaaac ggacctgtat gagcatacat
    13501 ttgataaagt ggcttccatc cagaaccttc gtgaacatcc gtatgaattc tatgaaaaat
    13561 taggttataa aatcgtaggt gtcttaccaa atgcaaatgg ctgggacaaa ccggatattt
    13621 ggatggcaaa aacgattatt cctcgaccaa attctcaata ataaaaagag gttgtgacag
    13681 aagtaatcag cttcaagaaa taagaaggaa tttacgaaaa ttacttcttg aatttttgtg
    13741 aaattccaac ttatttccga agaagctact tttggaacac cgtgtaccag aggttgtgaa
    13801 aaagtcgctt agtttcgagt agtaagaaaa attttgtgaa aatggctttc tacatttttg
    13861 cataaatttg gcttaatacc gagaaactgg cttttgaaca ccgtttattc agataaggga
    13921 ctgtgacaag acttttgtca cagtttcttt ttgtttattc ttttttatct ttgtatggca
    13981 ataatagaca atataacgaa aattatttaa tggcttttgg aagaccatgg aaaaccttgt
    14041 acaaagctat tttttctgaa aaattccttg aaacctcacg aaaaaatcat tattttatga
    14101 aaaagacaaa aaaagtgttg attttttaat aattattcat taaactctta aacaacttca
    14161 gaaaatatta attattctga aaattccaat aaaggggtac gtaaaatgaa aaagaaattt
    14221 acatttggtt tggttgcggt atgcggcctt gtacttgctg gatgttatgg cggcagttca
    14281 gccacaagca gtagttcagc aaaaagcggt tcagcagatg gaggaggcgt atttaactta
    14341 gtcgtgcctc aagaaatgcc tacagctgac ttatcagttg caacagatac aatcagtttt
    14401 acagcattga ataacgttta tgaaggaatt taccgtcttg atgaagacag caaaccacag
    14461 ccggcaggag ctagcgagtt ggcagaagtc agtgaagacg gattaactta caaaatcaaa
    14521 ttacgagaag acgcaaaatg gtcaaatggt gatcctgtta cagcagcgga ttacgtttat
    14581 ggctggcaac gaacagtaga cccagctaca gcttctgaat atgcttacct gtatgcgcca
    14641 gttgaaaatg cagaagacat tacagctgga aagaaagata aatcagaact agggatcaaa
    14701 gcagttggtg actatgaatt agaaatcaaa ttgacgaaac aaacaccata tttccaatat
    14761 ctgcttgctt tcccatcatt tttcccacaa aaacaatccg tagtggaaga aaatggggat
    14821 gcctatgcat ctgcaagtga taaagctgtt tataatggac cattcacatt agaagatttt
    14881 gatggaccag gaacagatac agaatggact tataagaaaa atgatcatta ctgggacaaa
    14941 gatacagtaa aactttctga aatcaaagtc agtgtagtaa aagaatcttc tactgcattg
    15001 aacttattca aagatggcca agcagatgac gtgatcttgt ctggtgagtt agcacagcaa
    15061 aacgcaaacg atccagctta tacttctgtt aaagaagcgc ggacaagcta tatcgaattc
    15121 aatcaacgtg aaaagaattc accattcaac aatgtgaacc taagaaaagc tatttcttat
    15181 tctatcgatc gtgaagcttt agtaaaacaa gtactaggtg acggatcagt tgtctctaca
    15241 ggattgatcc catcagatat ggtaaaaagt ccaacaacga acgaagactt tgcaaaagaa
    15301 gctggaaaat tagtttctta tgacaaagat aaagcaaaag aatattggga aaaagcgaaa
    15361 aaagaattgg gcgttgattc tttagaattt gatttgatgg cttctgatga tgattcatcg
    15421 aaaaaagtaa tcgaatatgt tcaaaactca atccaagaaa acttggatgg cgtaacagtc
    15481 aaaccaacac ctgttccatt ctctgtacgt cttgaccgct caacttcggg tgattttgac
    15541 gcagtactag gcggatgggc tgctgactat gcagacccaa gcagctttac tgatttgttt
    15601 gtcacaggta attcatacaa ccgtggtcgc tggagcaatg cagaatatga cgaagcagtt
    15661 aaagcagctt catcaacaga cgctggcgat gaacaagccc gttgggatga tttccaaaaa
    15721 gcaatcaaga tcatctctga tgatatgggt gtcgttccgg tgtaccaaaa agcagaaggt
    15781 cacctagtga atgaaaaaat caaaggtatc gttcaccatg cggcaggcgc ttcatgggat
    15841 tacaaatgga catacgttga agaataatcg ttaataccgt gagcatgaga aaaaacgagg
    15901 ctgcggcaaa tgtcgcaacc tcgttctcat attcacttat cctaacaaag aaaaaagcat
    15961 gaaaatagca gaaagagcaa ttagtattcc ggcaatgatc agccaaaagc tgtacatacc
    16021 gtagctggca gacgagagcg aggaaaattc tggttttttc tttcggttcc ttgttcgtgc
    16081 aagatggacc gatcgctgaa aatgatcgaa gaaacccgaa gaaaagaccc ataaaaaacc
    16141 gccgataatc agaaacggca atgaccataa gaatagatca ttagataatt gaatgagtgt
    16201 aaaggaatgg ttgatgagat tttttattaa aataaccaga atcagtagaa aagctactgc
    16261 gtaggggata gatttttttt tcatttgatt gctcctttat ttttggttca ttatctaata
    16321 atgtagcgaa acatctgtca gaagtcaaaa gctaggggga aacattagtg aatagttata
    16381 tcaaatatgt attaaaacgt gtctttttca tgatcatcac gctttggtta attgcaacaa
    16441 tcaccttttt cttgatgcaa ttgctgccgg gcacgccata tacgaatcag gaacgtttga
    16501 gtcctgaaac aatcgagatg ctaaataaac aagtcggttt ggataaacca gttatcgtac
    16561 aatatgggat ttatctttct aatttgcttc aaggagattt tggaatttcc ttccaattta
    16621 aaacccagcc agtcgcacat ttgttagctg gaagaatcgg accatccttg cagttagggt
    16681 tacaggcaat tatctttgga acagtcctag ggacgatttt aggaacgatc tctgccatga
    16741 agcaaaatac atgggcagat acatcttcta cactcgtagc gatattaggt cgttccattc
    16801 caaactttgt atttgctgtt ttattacaat atatctttgc aatcaaatta caagttttgc
    16861 caatcgcaaa atgggatggc tttgtgtaca caatcttacc aacaattgcg ttggccatgt
    16921 cgccgcttgc tgactctgct cggtttatcc gtacggaaat ggtggaagta ctgcatagtg
    16981 attatgtgga attagcaaaa gcaaaaggat tgagccgttg ggaaatcgcc tttaaacatg
    17041 gtcttcgaaa tagtttgatt ccattgatga ctttattagg accgttagct gtagcattga
    17101 tgaccggatc actggtggta gaaaatatct ttgctattcc tggtatcggg gaacaattcg
    17161 ttaagtcaat cacaacaaat gattatccta cgatcatggc tgtaacgatc ctttactcat
    17221 ttatgctgat ttttgttatt ttgatcgtgg atctattgta cggtctagtt gatccaagaa
    17281 ttcgtgtttc agaagggagc cgaggataaa tggaaatgat accaaagcgt tatgaaacag
    17341 ttgcagatat ccctgcggat gaatttcttc cattacaaaa aaataccgaa gaagaacgtg
    17401 aacagattac tgcaccttct ttgaatttta tccaagattc atggcgccgt ttaaagaaaa
    17461 acaaagctgc cgttatttca atggttttac tattggtcat cattttgatc tctgtgatca
    17521 caatctttgt ttctcctcat gatccaactg cccaaaacgt ggcttatatc aatttgcctc
    17581 ctcgtattcc gggaatcaat atcgatggat tgaatggaaa agcaatggtt ggtggtgaac
    17641 ttgttgataa atatgctcaa gcaaacgtcc cttcaaacgt aaatttcttt ttaggaacag
    17701 acggtttggg acgtgatgta ttaagccgct tatttatggg aatgagaatc tcgttgctga
    17761 tcgcatttat tgctgcatta ctagatgtaa cgattggtgt agcttacggg ttggtttctg
    17821 gtttgttagg cggacgtgtc gataacgtga tgcaacgttt tttggaaatc ttatcaggaa
    17881 ttccaaacct cgttgtcatg attttgatgt tggtcgtttt tgaaccagga attttttcaa
    17941 tcgtggctgc tatggccatc acaaactgga taccaatggc acgtatcgtt cgtgcacaaa
    18001 caatgaaatt aaaagatcaa gaatatgttt tagctggatt gacattaggt gaatcaagaa
    18061 tgaaaattgc attcaaacat attttgccga atatctctag tgtcattatt attcaaatga
    18121 tgtttagtat tccatctgct attttcttcg aagccttttt aagctttatc ggtttaggtc
    18181 ttacgcctcc gtcagcttca ttaggaacga tgttgagcga agggtacaag acattcctgt
    18241 atctgcctta tctattatgg attccggcag taactttatc ggttatcatg attggcttta
    18301 acttacttgc tgatggattg cgtgatgcct ttgatcctaa aatgaaagag tgaagacgat
    18361 gacgaaaatt ttagaagtga aagacttaga aatctctttt gatacgtatg ctggaaaggt
    18421 acgagcgatt cgcggtgtca attttcattt gaataaagga gaaacattgg cgatcgttgg
    18481 ggaatctgga agtggaaaat cagtgacgac cagaagcatc atgcgcttgc tgtcaagcaa
    18541 cgccaatata gatgctggtc aaatcctctt taaaggtaac gatatcgttg gaaaatcaga
    18601 aagagagatg caaaaaatcc gtggtaaaga aatagcgatg attttccaag atccaatgac
    18661 ctctttagat ccgacgatgc ccattgggaa gcaagtcgct gagtccctta gaaagcataa
    18721 taaagtttca aaaaaagagg gacaaaaagc tgcattagaa ttgcttaaat tagttggaat
    18781 acccgaagct gagaaacgta tcaacagtta tccgcatcag ttctcaggag gtcagcgtca
    18841 acggatcgtg atcgcgattg cactggtatg ttatccggaa atcctgattg ctgatgaacc
    18901 tacaacagcg cttgatgtga ctattcaagc acagattttg gagctgctga aagaaattca
    18961 gacaaaaatc gatacatcaa ttatctttat cactcatgac cttggtgtag tagcgaatgt
    19021 cgctgatcgt gtcgctgtca tgtatggagg aagaatcgtt gaagttggaa catcggaaga
    19081 aattttctac aacccgcaac atccctatac ttggggactg cttggttcaa tgccgacatt
    19141 agatagtgcg aacgatcgat tgtatgctat tcctggttct ccaccggatt tattgaaccc
    19201 gccaaaagga gacgcattct atccaagaaa tgaattcgcg atgaaaatcg atgcagaaca
    19261 agaaccacca ttttttgaac tatcaaaaac acacaaggca gcaacttggc tacttgctcc
    19321 gcaggcaccc aaagtgacac cgccagaaga aatccaacgt cgctgggcta tctttaaaga
    19381 gaaacaaaaa catacttacg gtcaaggagg aattgctgat gccaaataaa ctacttgaag
    19441 ttaaaggatt gaaacagtat ttcaatgtag gaaaaaagaa tgaagtacat gctgtaaatg
    19501 acatcagctt tcacatttat gaaggagaaa cattcggttt agttggagaa tctggaagcg
    19561 gaaaatccac tactggccgt acgatcattc gcttgaatga acctactgat ggtgagatat
    19621 tattcgacgg tcaagatata acgaagatca aagataaaaa aggtttgacg aaattccggc
    19681 atgatgttca gatgatcttt caagatccat acgcttcgtt gaatcctcgt atgaaagtca
    19741 gagatatcat tgccgaagga attgatgtta atggactagc taaatcatct gaagagcgtg
    19801 caaaaaaagt cgatgatcta ttgagaactg ttggattgaa tccaagccac ggtactcgtt
    19861 atcctcatga attttcaggt gggcaacgcc agcgtattgg tattgcacga gcattggcag
    19921 taaaaccgcg ttttatcatt tgtgatgaac caatttctgc actagatgtg tcgatccaag
    19981 cccaagtggt caatttgttg caagatctcc aaaaagaaca tcaattgacc tatctattta
    20041 ttgcacatga tttgtcgatg gttaaacata ttagtgaccg aatcggtgta atgcataacg
    20101 gcttgttatt agagatggga acaagtgatg aaatctataa tcacggtgtt catccttata
    20161 cagaaagttt gttatctgct attcctctac cagatccaga ccatgagaga aaacgcagaa
    20221 gaatcaaata tcaacctgaa ccagatgacg gacaagtacg tcaacttcgt gaaatcgcac
    20281 cagaacattt tgtctatgca actgagcagg aagtcccata ttacgcaaaa aaactaaaac
    20341 gacaaaagga atctcttctg gttgctaact aggagggaca tagatgctaa aagcttttaa
    20401 attccgtatg tatccgacag aagaacaaaa acagcaattg attcgtactt ttggatgtgc
    20461 tcgatttacc tataaccatt tgctgaaaaa gcggcagaaa agttggcaac aaacaggagt
    20521 agccaatttt tcgctcacac ccgctacatt aaaaaaagaa tacccattct taaaagaagt
    20581 agacagtctt gctttagcaa atgcacagct taatttggat cgggcttttc gcaattattt
    20641 caagggacgt gccagcttcc caaagcttaa aacgaaaaaa agtatgtggc aatcttatac
    20701 gaccaacaac caaacccgta cgatctatct ggaaaatggc tacttaaagt taccaaaaca
    20761 aaaagaacta atcaagataa atcagcatcg gccagttgaa ggatcgattc gctccgctac
    20821 gatttctgct cgatataatg aagaatttta tgtcgcacta ctttgtgatg tttcgccagt
    20881 aaaaaaagaa tctttagcta aatggatcgg gatcgcctat catccgaaga cattgatcca
    20941 aacatctcga cctctagaag taactttacc aaaatttcac cagacagaag aaaagctgca
    21001 acatgcacag cggaaattga atgtgaaagt ccgctccgct caccatagaa agatcaggtt
    21061 agatcaggca agcaattatc agaaacaaaa gagaaaagta atggatcttt atctgaaaca
    21121 aaagaaccag cgagaagatt atcttgaaca attatctggg aaattggtca aacaatatga
    21181 ctacttattt gtagaatctt ttccaaaaga agaggcacat gctgattttt ctattcacga
    21241 ctggcataaa ttaataacaa aattgcgtta taagtcccaa tggtataata aaaaatttct
    21301 tttgatcaat accgacggag cagaagaaag caattccgta agaaagagcc aagtagtaga
    21361 aaaaatgggc agacattcgg ttatcaaggg ataaaaaatg aatgaaactg ataggagcgt
    21421 tagggttagc cttgttaata aaaagtctta atgacttttg tttctaggaa tttttctttt
    21481 gaagaaaagc tcactaatta tgacaaacca ataaaacaat agcagaaaaa gttcgtacga
    21541 gctttttctg ctattgttaa ttttttattc agaaagttta cgaatacatc aaaattctga
    21601 aacaaaaaac gtaactcaca aagagttgtt tttgcgtttt ttcttgaatg attaggtctg
    21661 aatcttttgc tcacaacctt attcatggtg ccccggcttg agctgataga tttttgaagg
    21721 acggccgatt cctacaggac gttcaccgat ctcatcgaaa tattggagca tagctttctt
    21781 aaaattggaa tgatcgatcg ttttataatc gatccctaag aatttagcaa atacttttcg
    21841 agcttccgta atcgtgaaat ctttacctaa aacttgtaga acttgcggct cgtgttccat
    21901 tttattgact acacggttga atgctttcaa gatgatttga ctatggtcaa aagccaaagt
    21961 atctttgcca gaagactctc cagtgactaa atcaagcgag atagccactt ctccgctaga
    22021 taaatggatc ttgttactat gacgttctag tgtgaaccag cgtacttcct tggcatcatc
    22081 tccggcgatt agcggttctt ctccaataaa ggctaagtag ctgactgtga cgacccagcc
    22141 tcgcggatct cgattaggcg tactgaatgt atgcagttgc tcaatatttt cttttgaaat
    22201 aaccacacca gtttcttcct ttgtttctct taagacgctt tctccagttg actcatcctt
    22261 ttggacaaag ccaccaggca atgcccatga atttcgataa ggatgccctt ttctttggat
    22321 caacaaaact ttcagctgat cttcttcttt gttatagcac atcagtacga tatcgacagt
    22381 caaagagggc ttgtcatatt ctggacgttc ctgtttttga taccagttaa gaaattcttc
    22441 ttcacttgct ttatgttcat aatataattt ttcttcttct ttagaagcaa aacggttcat
    22501 ctgaccacct ccattgacag taaaagtact ttttacctta ttgtagcaga ctctgaaaaa
    22561 aaaccaagga tttacttgaa aaatctaggt tatcatttaa atatgaaaaa taaatggaag
    22621 tatgagattg aataaaaaga aaagcagata aaacggcaat actttatacc gctcttcacg
    22681 aatggcaaag aagccacaaa taacgatata tacgtcaatg ataaaacgca aaatccaagc
    22741 tgctgtcata aaactgttca aatgcccatg gaggttaaaa taaccataca tacgaatata
    22801 aaaatagctg aatattaaat gtgctaatga aagaaaagca atactaagtg taaaaaaaag
    22861 atgtttcttc tgcatgattg ttccagtccc ttactaagat agatagtctt tattatacca
    22921 cgtgtgaggg gagaaataaa aagccgtttt ttagtagata tgaaacaaaa caaaaacccg
    22981 catttattca acctattcat ccttttaaag gatagattga acgtagatag aagtcgttta
    23041 tccagtcttt ttcattttga aaaaaagcta acagcatgct ttttttatgg tatactagca
    23101 aggaaacgaa ttcgcatcat gcgataaagg aggaagagcc ccgtggcaga aaaggaaact
    23161 ttttatatca ctacgccaat ctattatcca agcggcaaac ttcatatcgg caactcgtat
    23221 actacgattg catgtgacgc aattgctcgt tataaacggt tgatgggctt tgatgtgttt
    23281 tatctcactg gagtggatga acatggtcaa aaaatcgaaa caaaagcaga agaactaggt
    23341 gtaaaaccgc aagaatatgt agataaaatg gcggctgatg tcaagaaatt atggaaaacg
    23401 cttgatatca gttatgataa attcattcgc acgacagatg attaccataa agcagctgtt
    23461 caaaaaatat ttgatcgttt attagaacag ggagatattt acttaggtga atatgaaggc
    23521 tggtactctg tttctgacga agaattcttt acagaaacac aacttgcaga agtgtacaaa
    23581 gatgacgaag gtaacgtgat cggtggtaaa gcgccaagtg gacacgaagt agaattggta
    23641 aaagaagaat catacttctt ccgcatgagc aaatacgcag accgtctatt ggaatactat
    23701 gaagaacatc ccgaattcat ccagccagaa tctcgtaaaa acgaaatgat caacaacttt
    23761 atcaaaccag gattagagga tcttgcagtt tcacgaacaa cttttacttg gggagtacca
    23821 gtcaagagtg atccgaaaca tgtggtgtat gtatggatcg atgcattatc caattatatt
    23881 actgcactag gatatggctc cgaagatgaa agtctattcg aaaaatactg gcctgcagat
    23941 gttcagatgg tcggtaaaga aatcgttcgc tttcatacga tctattggcc aatcatgctg
    24001 atggcccttg atttgcctct acctaaaaaa gtatttgggc atggctggct attgatgaaa
    24061 gacggaaaaa tgtctaaatc aaaaggaaat gtcgtttatc ctgaaatgct tgtggaacgt
    24121 tatggtttag atgcactccg ttattatttg cttcgtgctg ttccgtttgg gtcagatggt
    24181 gtctttacgc cagaagattt tgtttcccgt gtcaattatg atctggcaaa tgatctaggg
    24241 aacttattga atcgaacgat tgctatgatc aacaaatatt gtgatggact cgttcctgac
    24301 tatgcctcac ttgtcactcc atttgatagt gaactgtcta cgacggctgc taacgttgtc
    24361 ggacgttacc atgatgcaat ggaaaaaatg gaattcaata cagcattggc tgaaatctgg
    24421 gtgctgattt ctcgtgcaaa caaatacatt gatgaaacag aaccatgggt attagcaaaa
    24481 gacgaagaaa agaaagctga attgaatagt gtcatgatcc atttagctga atctttgcgt
    24541 atcgcagcga tattacttca gccaatcatg acagaaacgc cagagaagat cttcaatcaa
    24601 ctaggattgg actctgaaac aatgaatctt gaaggattac actttggcga atttccttca
    24661 ggaacaaaag tagttgcaaa aggtacacca atcttcccac gtttagatat ggaagaagaa
    24721 gttgctttta ttcaagaaaa aatgtctgaa ggtactcaaa caaacgaaga tacagtcaaa
    24781 tgggatccag aagaaacaga acttgtttca acgaaagaaa aacaaatcaa atttgatgta
    24841 tttgaaaaag tagaactaaa agtagcagaa gtcatcaact gtcaaaaagt agaaggggca
    24901 gataagttgc tgcaattccg actagatgct ggagacagcc aagaccgtca aatcttgtca
    24961 ggaatcgctg aattttatcc tgatccaagc gaattgatcg ggaaaaaagt cgtcattgta
    25021 gcaaatctga aaccacgaaa gatgcgtgga caaatcagtc aaggaatgat cctttctgca
    25081 gaagcaccag atggctcttt acaagtaatc gaagcaccaa aatccatgcc aaatggctca
    25141 gaaatcgcat agaaattcaa agggggtatg acactagttg tgtcataccc cctttttccg
    25201 aaatttgaga agcaattttc gtaaattcct tcttattact tgaagccaat catataatac
    25261 agaaacagag aactatccaa aataaatcct agaaaaagaa gtacgagctt cgctgatttt
    25321 tgttaattta gaataatact aataggaatc gtaaaaacag aaaaaaagca taatgataaa
    25381 gggtcgggca gattttaatt gattcatctg gtactctttt ttattgtcct tacattcata
    25441 aagtttgaat gcaatgactt tattacatct atatttatat ctaacagtag cgttgatgtg
    25501 ttaattataa gttctatcac tttatgttca attagtttgt gctcttatat gtgtgattga
    25561 aaatatagat aaaaaaacaa tcatcggctt tgacttcgat gattgttttc tttattttgt
    25621 aaaaatccta tcacttgatt ttatggtaac cttttatttt tgtcttcaaa cggcttggta
    25681 agagagcagt aagcagtgca aatgggatcg aaaagacata ccagaaaatc gtacgtccga
    25741 taccataatg ttgatagagc tttgtcaaca tcacgtgtaa caagatcaac cctaaaagca
    25801 aggagccagc tataaaccaa tgattatccc aatgcatgac ttcactaagt gccatcactc
    25861 caaaaggata gaaataaaaa tagatcccga ctaaggtcat ccgccagttc tttgtaaatg
    25921 ttccgatatt caataaaaag aaaatcgctg aaagcaaaat accgataggc ggaaaaagcc
    25981 caaccaaaaa ggaatacaac atcccccaca agatcatcac aggacctttg atcaatgcaa
    26041 cgattgcgat gaacaaagtc agcaatatta gtttttgtga taacgttgca acagtcatta
    26101 atccaaataa aattaatgtg aaccaatgcc aatgggactg ctgttgttct ttacgggaaa
    26161 aatcgacccg gttggataaa taatctgcta atttcggata agaacgctta aaatccataa
    26221 actgttcctc cttcgtggaa aaggtaggtt tagtatacga aaaataaaaa agaaatacat
    26281 ccgtcttaag agggagtttt tcactgaaag tggagaaaaa agaatggtaa attaaaatat
    26341 tctcagttat actgaaaatt ataccaaatt tcaaagaaga aagaggatgg gaatgaaagg
    26401 caaactaaaa cgagaaatca atctgtttgg cgcattagct accgttatgg gaaccgtgat
    26461 cggtgcaggc gtcttcttca aaactgctgc tgttactgct agtactcagt ctacaagttt
    26521 gacattgcta gcttggcttt tgggtggttt cttaacgatc tgtgctggat tgacagtggc
    26581 tgaattagct acagcaatcc cggaaactgg tggagctgta aaatatattg aagctgcgta
    26641 tggaaaattg cccagctttt tattaggatg ggcgcaaagc ttgatttact ttcctgctaa
    26701 tattgctgca ttatcgatta tctttgcgac acaattgacg aacttattac aattatctac
    26761 cgattatctt ttgttgattg cagtgatcac cgctgtttct gtgacagggt tgaatttgtt
    26821 agggacaaaa gtcggtgctt ctgtacaatc agtgacgttg attgttaaat taataccaat
    26881 tgctgtgatt gtcatatggg gattattgac cccaggacaa ggaactgtcc agttatttcc
    26941 aatcgaagct ggaaaagatg ttacttttgt cgaaggattg agcagtgcgt tgttagcaac
    27001 gttgtttgct tatgacggct ggttaggtgt cggtgcaatg gcaggggaaa tgaaacggcc
    27061 ggaaaaagat ttgcctaaag caattattct tggtttgagt tttgtaacag tcgtttatct
    27121 attgatcaat tttgtttttt tgaaaacttt gccgattgat catcttgccg gtaatttgaa
    27181 tgcagcttct gaagcatcag acgtcatttt tggaggaatc ggtggaaagc tggtcactat
    27241 tgggatcttg atctcggtat acggtgcatt gaacggttat acactaactg ggatccgcgt
    27301 gccttatgcg atggctttag aagacgagct acctttcagt aaacagctga caaagctttc
    27361 aaagaagttt acggttcctt atgttcctgc ggttttccag ttagcagtag cttgtattat
    27421 gatgagcctt ggttctttcg actttttaac agacatgttg atttttgtga tgtggctatt
    27481 cagtttactg atttttatcg gtgtctttat tttaagaaaa aaagcgccgg aattgccacg
    27541 tccatataaa gtaccacttt atccaatcgt tccgattatt gcgattctcg gtgctatttt
    27601 cattttaggt atgacgatga tgacgcaaac gaaattagca ttgatcggta taggtgttac
    27661 cttgataggt atcccagtct attatcaaaa aaagaaaaaa cgctcagaag agtaaaatat
    27721 ttcaacaaca gacagaaaaa gtacgaacta ggtcctctag atcttcgtgc tttttctatt
    27781 tcaataaaac aagttcttct attttgattt ttgctacttc tgcaagtagt gcttatgtgc
    27841 taaagtaaga atgaaaagga gagataaaca tgatatttga ttctcatacc catttaaatg
    27901 ctgaacagtt caatgaagat attccagaaa cgattcagcg agcacaagaa atgggggtaa
    27961 cgaaaatggc ggtcgtgggc ttcgatacgc caacgattga aaagtctttg caattaagcc
    28021 atgactatcc aaatatatac agtattatcg gctggcatcc gacagaggct ggcagttata
    28081 cgaaagaaat cgaaaataaa ttacaagaac aattgacttt accaaaggtt gtagcattag
    28141 gggaaattgg cttggattat cattggatgg aagacccgaa agaagtccaa gataaagtat
    28201 ttcgcagaca gattgctatc gcaaaagaaa tgaacctacc aatcagtatt catactagag
    28261 aagcacttga agacacgtat caaatcctaa aagaagaaga tgttcgagat atcggtggaa
    28321 tcatgcatag tttcagtggt gattatgaat gggcaaaacg atttcttgac ttagggatgc
    28381 atatttcatt tagcggtgtc gtcactttca aaaaagcatt agacgtccaa gaggctgcag
    28441 caaatgtacc aatcgaacga ttacttgtgg aaacagatgc cccttatctg gcaccagttc
    28501 cttttagagg aaagcgaaat gaaccaggct atactcgtta tacagtagaa aagattgctg
    28561 aacttcggaa tcttccgaca gaagaagtgg ctgcccaaac atggacaaat gcgcaccgat
    28621 tatttggtct aagcgaacat ggataagatg aagatccaag agattatagt cgttgaagga
    28681 aaagacgata caagaaggct gcgggaagta gttgatgcag atacgataga aacaataggg
    28741 tctgcaatca atgaagagat cctgatgcaa attgaacatg cccaagagac tcgtggagtg
    28801 atcgttttta ccgatcctga tttttcagga gaaaaaataa gaaaaatcat tatggaagct
    28861 gttcctcagg caaaacatgc ttttttgccg cgcacacaag ctaaaccaaa gaaaaaggga
    28921 agccttggtg tcgagcatgc aagtgatgct gctattttag aagcattgaa aaaggtcgtg
    28981 acgccagaca tttcccaaac ggctgtttct gaaatcacta gacaagacct tttagactat
    29041 ggtttaatag ctggggcaca agcaaaagaa aaacgagaaa aactaggtga cgagttgcgc
    29101 atcggttaca cgaacggcaa acaattggaa aaacgtttga agatgtttcg tattacgccg
    29161 aaagaactcg cccaagcaat gaaaatagtg gaggaacaac atgagtgaat atcgtgaaat
    29221 tgcgacaccc tctagaacaa aagagatttt attgaaacat ggtttttcat ttaaaaaaag
    29281 tttaggacaa aattttctga ctgaaccaaa tattttaagg aaaatcgtag aaactgcgca
    29341 aatagatgaa catacgaacg tgatcgaagt tggaccagga atcggtgcat tgacggaaca
    29401 attagccaag catgcaaaac aagtcgtagc atttgagatc gatgatcgtt tgatccctgt
    29461 attggctgat acgatgcaac cctatgacaa tgtgactatt gtacatcaag atattttaaa
    29521 gaccgatttg tcaacagctg ttagagaaac atttcatgag gagcttccgt taaaagtcgt
    29581 agcgaattta ccttactata ttacgacacc gatcatgatg cattttcttg aatcagattt
    29641 ggttgtggat gaactagtcg tcatgatgca aaaagaagta gctgatcgta tctctgctga
    29701 accaggaacg aaagcttatg gttcattatc gattgctgtt caatattata tggaagccag
    29761 tttagcattc atcgtaccaa aaacagtatt tgtccctcag ccaaatgtag attcagcgat
    29821 tttgaaactg acaagaagag atataccggc agtcgaagtg acagacgaaa aagcattttt
    29881 ccgattgaca aaagcggcat ttcagcaaag aagaaaaacg ctttggaata acttgcagca
    29941 ttcgtatggc aaagatgacc agacaaaagc atggttagca aaaagcttgg aaacagctgg
    30001 aatcgatcca aaacgtcgtg gggagacttt gtcattacaa gaattcgccg cattaagcaa
    30061 tgcgatgtca gaaaatatgc agtaaaaaaa gaggttgtga cagaagttgt gaaaaagctg
    30121 tcctgcatca agtaataaga acagccaaac aaaaatagtt cctcatgttt ttcgtttgtt
    30181 tgggcttatt accgcagatg caagcttttg aacaccgttt aagaaagagg ttgtgggcct
    30241 gccgtttaac tctaagtcac aaggaacaat ttcaaaaaac agcttctcat gtttttgagt
    30301 tagttggtct tattacttga tgcaagcttt tgaccactat tatgccgaac aaggagatgt
    30361 gacacaaatt ttgtcacatc tcctattttt gtttcttgat caaaaaattc ttatacttga
    30421 tactcacact cattttgtat ggatttagaa aagaatatgt gtcttgacag ttattagtaa
    30481 gtgagttata ctaagtcgac atttatgtgt caagacatat taggagagag aaaaaatgag
    30541 aaaaaattca gttcgaaaac taacgatttc tgctttattg attgggatgg gggtcattat
    30601 cccaatggtc atgcctaaaa tcatgattcc accagcttcc tttactttgg cgtctcatgt
    30661 gccattattt attgcgatgt tttttacacc aggagttgca gtggctgttg cgctaggtac
    30721 gacatttggt ttctttttaa caacgccggt tatcatcgca ttgcgagcat tgtcacatct
    30781 tgtgtttgcg ttgattgggg cttggtactt gcaaaagcat ccgagtatcg ttttaaaaaa
    30841 tggacagttt acttttgcta attggcgttt ccaagggttc aattttgtga tcggtgtgat
    30901 tcattcttta gcagaaatgc tagtagtcag catcttttac tttattggta atatgcctga
    30961 aacatattat tctcaaggat atttttatac agtattcatc ttgatgggga ttggtgggct
    31021 tatccacagt ttagttgatt ataatattgc ttattttata gcaggaacac tcagcaaata
    31081 ttttgatatc cccgtattta cggcagcaaa aaaagaaaat cggaaagagt cgattcaagg
    31141 gtacgcgaag aaaacgacat attagacatg atctctcaaa aaaaaaactc tcatctagta
    31201 atggataata aatcctctaa gatgagagtt ttttgtccta aaaagagctg caccaacatc
    31261 ttctggcaca gctctaacag ggggcaattt atggaagttt gatgacttgt tctgtttctt
    31321 tatcaaagaa gtggcctttg ctgatgttga aggcaaggtc gactatttcg cctggtttat
    31381 ggaaatctct tgcatctact tttgagatga actcagtaga accagttttt gtgtaaagca
    31441 tcgtttcagc tccaagtaat tcggaaacga caacttctga tttcactacg gcttcaggtg
    31501 aagcttcaag ggctacttgt tcactgtgga tgtcttctgg acgaataccg aagataactt
    31561 cttttccttc ataacctttt tcaactaata ctttgttttt tccttcagga atacgaagct
    31621 taagcccatg tccatctgtg ataacaccat ttttcaatgt cacattaaag aagttcatgg
    31681 caggagatcc aataaagccg gcaacgaaca tattgacggg tgtatcataa acttctttcg
    31741 gtgtaccgat ttgttggata aatccgtctt tcatgataac gattcggtca gccatagtca
    31801 ttgcttctgt ctgatcgtga gtaacataga tggtcgttgt ttcaagacgc tggtgaagtt
    31861 tggcaatctc agcacgcatg gctacacgta atttagcatc taaatttgat aatggctcat
    31921 ccattaagaa gacttttgca tcccgaacga ttgcccgtcc caatgccaca cgttggcgtt
    31981 gtccaccaga taaagcagct ggttttcgtt tcaagtattc tgtcagacct aagatctctg
    32041 ctgcattgtc cacacgtttt ttgatgtctg ctttatcata tttacgtaat ttcaagccaa
    32101 aagccatatt atcaaaaaca gtcatatgag gatacaatgc gtagttttgg aaaaccatgg
    32161 caatatcacg gtctttaggt gccacgtcat tcatgacttt tccgccgata tttagttctc
    32221 cttcagagat atcttccagt cccgcgatca ttcgcaaagt agttgacttt ccacaaccgg
    32281 aaggaccaac aaaaacgata aattcacggt ctttgattga tagattaaaa tcagttacag
    32341 aataattttc tgcattgtca tattttttat atacgttttt cagagccatt tctaccataa
    32401 tacgttccac actttctttt ttagttttat taactattta aagtataaat gaaagcgtta
    32461 actaacttca atgtcatgtt gaacaagaat tttttctttt ttttgtcaat gtgctagttt
    32521 taagctttaa taaatatcca taagaaataa aaactgatac actggagtaa ataagtatgt
    32581 taacaatatc aaaaggagtg tctcttatga aaatcgcttt gatcgctcat gaccgaaaaa
    32641 aacctatgat ggtgaaatta gcaacagcgt ataaaacaat attggaaaaa catgaacttt
    32701 ttgctaccgg gacgactggg cagaggatca cggaagcaac cggcttgccg atccatcggt
    32761 ttaaatccgg accgttaggc ggggatcagc aaattggagc catgatttcg gaggatcagt
    32821 tagatttggt gatttttctt cgagacccgc tggctgcaca gccccatgaa ccagatgtaa
    32881 cagcacttat ccgtttatct gatgtctatg agattccgtt agctacgaat atcggaacag
    32941 ctgaggtgct actaagagga ctggaagccg gcttcctaga ttttcgaaga atcgtccatg
    33001 aaatagacaa gcatccactt tcattttgat ggataagcgt atggaaaaat aacgtttaat
    33061 gttcgcctat atgtagctat aaaagctaaa caaactgata atatgcgata taatacgaac
    33121 gtattggata atataaacaa taatattagt ttttcgtatt tgcagtaaat gtgaaaatat
    33181 gctatagttt ctgtgggaaa agatcccaaa aataatacag agtagaaaat aaagcgttaa
    33241 gtgctaagag gatgggatgt tgcctcttgg acgaaggacg taatgttcgc ggttttattt
    33301 tcgcattcgc tgcatgatac gatgtagcag ctcttaaagg agatgctaaa aatgaagaaa
    33361 caccggttag acgcacgtat gattgctatt atgggcttat tgattgcatt gatggtcact
    33421 ttgtcccgac tggtagcaat cgagacccca tttattaaaa tcagtgtcac atttattcca
    33481 caagtgatca tgggcattct ttttggtcct ttttggtcag ggataggcgc agttttagct
    33541 gatttagtag gaatggccct cttctcgaaa tctgcattct ttattggatt tacattgaat
    33601 gcatttattg aaggagcaat ctacggattc tttttctatc gaaaagagat cacttggaaa
    33661 aatgccattc tggctacgct tagtgtcacg ctgatcatca acttattttt gacaccatta
    33721 tggcttgcgt tgatgtacca tgtgccattg ttcagctggg tcgtttgggc gccccgcctg
    33781 ttaaaaacag taatatggtt accgattcaa tcaattgcca tttattacgt aggacgtagt
    33841 attccttaca aaaaaatttt aagaagttta gcgatccacg ctaaataaaa aacaagcagt
    33901 cttcccatcc cagaagactg cttgttttta ttgtgctgtg aattgtgctt gatagagccg
    33961 tcggtaataa ccatcttttt gaagcagctc atcatgggtg cccatttcga caatagctcc
    34021 ctgatccatc actaatatct ggtccgcatt tttgattgtg gacaggcgat gggcaatcac
    34081 aaaactggtt tttccttcca tcattgctaa gaaggcttgt tggatttttt tctctgtcaa
    34141 tgtatcgact gagctggtag cttcatctaa gatcaacata gggggattac tgatcatcgt
    34201 tcgagcaatc gtcaacagtt ggcgttgtcc atctgatatc tttaaccctt gaccgccaat
    34261 cttagtatct aatttttccg gcaaacgttc tacaaattca tacatataag aggcttttag
    34321 ggcatcattg atttctgcgt cacttgcttc cggattccca aaacgaagat tttctcgcaa
    34381 tgtactgtca aatagccaag tatcttgtaa caccattcca aaacttttac gtaatgtatc
    34441 acgttggata gagcggatgt catggtcatc gactgtaatt gttccttttg ttgtgtcata
    34501 aaaacgcatc agcaaattaa caagtgtgga ttttccggcc cctgtttttc ctactatagc
    34561 aatggtttga cctggataag cagtaaaatt gaaatcttcg atcaaacgct gcttggggtc
    34621 ataagaaaaa gaaacatgat caaaagagac ttttcctttg atatttttgg gttccaaggc
    34681 ataggcatct ggcaaatcag gcttttcttc tggctgatcg atcaaatcaa atgctcgttc
    34741 tagaccagaa aaagcggttt gcagttgtgt cgtgattcca gaaagttcga taaatggttt
    34801 agaaaactga cttgagtaga tcgtaaagct ggaaatcaca ccaacagtga ttgacgaacc
    34861 actcttcaat gccaataggc cgccaactaa accaatcgat aaataagcaa ggtgatctac
    34921 aaaacgagaa gacgggtttg tcaaggaaga agaaaattgt gcccgttgtc ctttttcata
    34981 tagatcagca tttagcagtt caaattgctg ttgactagct tcttcttgct gaaaagcttt
    35041 cacgattttc tggttaccga ttcgttcggt cacaaagccc gagatatccc caataatcct
    35101 ttgctgtcta tcgaaatttg tttgtgaagc acgagcaacg atccaactca caaggaaaat
    35161 aattggtgta gaacaaagaa cgaccaatgt cagaagtgga cttagacgca tcataaaaat
    35221 aaacgaaaga atgatgattg ccactccaga aaataattga ttgaaggccg cagaaattgc
    35281 aatggaaata ttgtccatat catttgtaaa tcgactgacg atatttccgt gggagttttg
    35341 atcataataa cgaagtggca atcgattcag atgagcaaat gcatcttttc ttaattttgc
    35401 aacggataag taagctaacc gattgcttaa cacttggatg agccattgac tgactacgtt
    35461 gattaaaacg ataccaccga atagaataag taaatggaac agtcgattga agcggacctg
    35521 tccttctcca atcatttgat cgatactttg accaatttgt aacgtcatca caactgttgc
    35581 aatcccattg atgattccta gtatcacagc tagccaaatg tcttttgcat aggcagtaag
    35641 gtaaggaatg aatcggcgga gcgtctgcaa ggataatttt tttactttca taactattct
    35701 tcctcctgtg atgcgacgat ttcctgatat tctgctgatt gagcaagtaa ttcttcatgg
    35761 gtaccctgag cagcaatctt accttgatcc atcactaaga tatgatgtgc ttcttgaata
    35821 gagcggacac gttgggagat aataatcact gtactgccaa gataagtctg tagcgcctta
    35881 cgcaaatcca agtctgtttg ataatccaac gcacttaaag agtcatctaa aatcagtaat
    35941 gctggcttgg caatcaaagc tcttgcaatc gtcagtcgct gtttttgtcc gccagagaaa
    36001 tttttcccat tttccatgac ttttgtatct aaaccatttg gaagctgacg gacaaattct
    36061 tctgcctgag cgattttcag agcttcccaa cattcttttt ctgtggcgtc tttcttaccc
    36121 cattgaaggt tttcacgaat agtcccggta aatagtacag aagtttgggg aacaagagca
    36181 atttgctgac ggagatgatc cagctgccaa gaacgaacat ccattccgtc cattataact
    36241 gtaccggaac tgacatcata gaaacgcgga atcaattgtg tcaaagtcgt tttcccgctt
    36301 ccggttggac caatgattcc aaggactgta tttcgcttca gctgaaatgt aatattttgg
    36361 agagaaagac cagaatcagg agtataacgg aagtcaacat ggtcaaaagc gataattgct
    36421 tcagaagaaa aatcgggagt agtactgacc tcagcttcaa gaatcgaatt ttctgtgtct
    36481 agcacctctt tcacccgatt tcctgaagct tcggcacgtg tgaagatcac gacgaggttt
    36541 gaaacaacga tcagtgccaa aagcatttga ttcatataat tgatcaaagc aagaacttgt
    36601 ccttgttgca agctaccaat atttactttg atcccgccaa ctgtcagcaa acagatgatc
    36661 ccgacattca tgatcaaggt tgtagcaggt gataataggg cagagatatt ggaaacacgt
    36721 aaataattgt tcgctagatc atttgtgctt ttatcgaact tctctgtttc tttttttgtc
    36781 tgcgcaaatg cgcggatgac acgaacaccg ctaagattct gactaacgtg ttcattgagc
    36841 tgatctagtt tttcttgcac tttttggtag agaggaacgg tttttttgat gataaaaaat
    36901 aaaatgattg agaaaatagg caataatgct aagaaaaaca gacctacttc ccagtcgatc
    36961 acaaaagcca tgaccactga cccgatactt aaaaacggtg ctctgatcaa taaacgaatg
    37021 accattgcta aagctagctg aagctgattg atgtcgtttg tcattcgggt gatcaaggta
    37081 tctgttccaa aatgattcaa ctcgttgtga gagaaagtat tgattttttt gattagctga
    37141 ttacgtaact ctgtaccaaa tccttgtgaa gctactgaag catagtattg gcaaatgata
    37201 gcacaaatca gaccaatcac agacatagcg accatccata agcccatttc aatgattttt
    37261 cctcggtcat tcatttttag tccattatcg atcaaggaag ccatcattaa aggcaggaca
    37321 agttcgaaga cagcttcaag aaatttgaag aacgggccca aaatgatttg cttacgatag
    37381 tcttttgcat aacgtaataa ctgaatcata tgattcctcc tattatttat ttgtccacaa
    37441 ttgaaaaaac aagtactacc acattgtagc ttaggaaatt tagaatgaaa agagaacaag
    37501 ccttttcata aatgaaagtt ttattatgaa gaagctttag aaattgaata gactattttt
    37561 tttaaaaaaa agaaaatgag aaaacatgcc agtctcttca ttcataggaa cgtctatttt
    37621 acttaatttt tctataaatg aattctgcat aaaaaatata tcaagtaaat gtttatagat
    37681 gaaactctat ttacttcttt tttaatttgt tcttgcaatc ttttttgcta cgtaattttt
    37741 gtaaaaaagt gggttgagag aaatctaatt gattttcaaa gaaggagtat gaaaatgaga
    37801 aaaatattta ttcgtttatt gtgggtacta tcttagagga ataaataata gtggagaaaa
    37861 ctatggtttg gcgcagattc tatcaggttt gatggaacga agacaacctc ccgacatcaa
    37921 gtcaaaagct acttgagatt ttgatctgaa aataaaaaaa gaaaacaagg taggaacatc
    37981 aatgtttcta ccttgttttc gtaatcaatg ggaaaaaact aagagtggtg tacgtaatca
    38041 ataaaaagga tggtgacaac agtacctctt tactctctga aagcatcata actcgttttt
    38101 cctcattatg ccaataaatt gttgttatac cacatataag gatttgtaat agctaaaaac
    38161 agacaggaaa gttgaaatct gtgaatctta ttttgtatgg aaggatttat agaacgcaaa
    38221 aatcaagata aagatgaata aaaatcctgt ttcggctata tattgcgtat ctacgccaat
    38281 aaaacgagtt tgttctgtca tagccatata aagcaaaggc aaaaatacaa ctacagcgag
    38341 ataagatccg atgatttctc gaaaagtttt ccaggaagta tgtttcctgt ttttatattt
    38401 atccgatttc attgaatagt catagcctcc ttattctttc atatgttgaa attccagtat
    38461 aaaaactgga aggaactgta cgttttttag aataaaaatt ataagggata agtaggctgc
    38521 tgtctataat aagatatatt tttcaattct ttattaaaga ttttattgac aaaatgaatc
    38581 cgttttctat gatggaggag gggtgaataa gttgttgaag aaggaaattt tatgttactt
    38641 agagaaccag acagcctttt tcgatttaga acatatgaac gaggtcttta cagcacaaag
    38701 gttagctgat cattttgggg taaaaagaaa cacagtcagt cattatttga accagttaaa
    38761 tgatgagcaa ctactagtca aaatcaattc tcgaccagtg atttatttcc acaaagaagc
    38821 ttttgaaaaa caatttttta agttacgcac gaatttttat ttttctatcg atgatctcaa
    38881 agaggaacag ccttttttcg cgcaaccaaa agacttattc tcttttatga tcggatacga
    38941 cgccagtttg aaagaaagta tcgaacaaat caaaacagct ctttactatc cagatggcgg
    39001 attaccactt ttgattacag gcgaaagtgg cacaggtaaa agttatttag ttaatttggt
    39061 ctatcagtat tgtctgcttc atgatctgct agaagattct gcaccattca tcacttttaa
    39121 ttgtgcacaa tatgcagata atcctgaact tttgactagc aatttgtttg gacatgttaa
    39181 gggagcgtac actggtgcag aagaaaataa aaaaggggct tttgaagcag cagatggtgg
    39241 gatcttgttt ttagacgagg tacatcgctt aacaccagaa ggtcaggaaa aactgttcac
    39301 ctatcttgat caaggtgtga tttatcgtat gggagaacct aatttgtcac gccggatcaa
    39361 aacacgtctc ttttttgcta cgactgaaga gattactagt catttcttaa caactttcat
    39421 tcgaagaata cctatccgaa tcgaactacc tgcacttaat cagcgtagtc gtaatgaacg
    39481 gctagaactg atttactctt tttttctcga agaacaaaga aaaatgggga gccctttgtc
    39541 agtcagtgga ccagctttgt cacttttaac aagtcagaaa ttatccggaa acataggaga
    39601 gctgaaaaat atcgtcaaag tttcagcagc aaaagcatat gctgaacagc gtgaacagcc
    39661 tgaaatccat gtcacgatcc atcatttgca aaaagaacta cttgcgcagc ctattactaa
    39721 aaatacagca cagcaaggaa tctatattac gcaagaccag accttagagc aattaatgga
    39781 gaagcaacag cccgaacagc agcgaatcgt taaaagtttt gagcaaatcc taattgattt
    39841 caagaaaaat aactgtctgc tatattcttg cgaaggaaaa ttaaagcaag aagtgattca
    39901 attatttgat tttttgctgt ttgagaccag tagacaagaa aaacacgagc tgctggttta
    39961 ttggacacaa tctatccgag agacctttcg acaaatggaa actgcctatc aaatcaaatt
    40021 cgatggaaac agtgtctatg ccttgagtta ctatctctat cagcgaagca ctatcaaatg
    40081 gttaccggaa gaacatgata ttatccaact aatcaaagaa ttagaacaac aagtttctca
    40141 gtcttatcca tctagttatc actatgtcca acgaattctg gaattaagta agatcaaatt
    40201 agatattgaa gacacaagta tggatcggat tttactgacg atctatctaa aaaaagcgaa
    40261 atggtcaaaa gaaaaacgac tgccaaaagc gatgattgct gctcacggtt atgcaactgc
    40321 tagcagtatg gcaaatgtag taaatcgttt attacaagag gatctatttg aatcatttga
    40381 tatgccacta gatgtcacac cacagcagat tgcttcagaa atccttgatt attgcgaaaa
    40441 cagcgatgtt tcaaatggat tgatcatatt agtagacatg ggatctctga aagaaatcca
    40501 tcagtttttt aaaaaacagt tatccgtacc gcttttgatt ttgaataatg tgacgacacc
    40561 tttagcaatc acagtagggg aatgcctgca aaaaaatgta tcattagaag agatagcaga
    40621 agagactgtt cgacagatcc agccagaatg gcgactgctc tatccagagg aaaacaaacc
    40681 caaagcactc attactactt gcttcactgg aatcggtacg gcggtccact taagtgaact
    40741 gctagaaaaa agcttaccta cggcttgtca gttgaaaatc atcccatatg aatatcagca
    40801 attaaaagat aagaaaaaca gtgacccatt attttccata tacgaagtcg taggaatgat
    40861 tggcaccaca gatcctgata tcaccaatat cgactatctt tcattagaag acctcatctc
    40921 gggggaaaag atgtctgtac tagctgaatg gttggacact actatgaatg cttcagagaa
    40981 ggaaatattc aatcagcgca tcattcgtaa tttttcattg gaaaaagtac tggattccgt
    41041 gactattcta gatacagaga aggtgatggg agaaatcgat cattttatga gagaattaga
    41101 ggtgcagttg aatcgaagca tcagcaatcc caaaaaatta gcgttgtatg tccatgtgag
    41161 ctgtctcatt gaacgattga tccgacaaat gccaatcgaa acctatcaag gattagagaa
    41221 atggaagcag tgtcaaaaag aagggttatc tgctattaaa tctgcgttta gtgtcattga
    41281 agagcattat agtgtcatga tccccaattc tgagattgcc tatatctatg atattttgag
    41341 tgaagataca gagtttctct cgatagaaga agaattttga acataagcaa gttgttgcca
    41401 ctaattttgg catgcaactt gcttttttag tatgtgtaag tgaaaagagg agatgaaaaa
    41461 gtggatagag aaattatctt agcttcccat ggaaaatttg cttcagggat attagattca
    41521 ttagagctga tctatgggaa aaatcattct attactgtat tcgattgcta tactgatgag
    41581 aattttgatt tagcggaaac agtaaggcag ctttttatga ggtacaaaga taaagaaatc
    41641 attgttctga cggatctttt tggcggaagt gtcaacaacg aattcttaca atatatcaat
    41701 cgggatcatg tctatctcgt tgccggattg aatttgccac tattgattga gctagtatct
    41761 cggttggacg ctgaagtaga gacaactgtt ttgatccagc aggtgctaac tgattcaaaa
    41821 aaaatgatcc agttttgtaa cgagcggctc aatcagaaaa tagaagaaga cgaattttag
    41881 gaggaagaaa aatgattgta ttgacaagag tcgaccatcg gttattacac ggacaagtag
    41941 ctttttcatg gacacaaaca ataggcgcag actgtatttt gattgctaat gatgatgtac
    42001 ctacgaatga gatacgaaag acaacgatca aattagccaa gccacaagga gtcaaactag
    42061 tgatcaaatc aattgatgac tcgattgccg cgttgaaaag cggggtgaca gataaatata
    42121 agttattcat cgtagtggaa tcgatcgagg atgcatataa gctggcagaa gcgtatccag
    42181 aaatcaaaac catcaactta ggagggatca aggcaaaacc tggtactcgc agcatcggaa
    42241 aagcggtaaa tattttacca gaagaggagg aacgcttgaa acgattaatt gacaaacaaa
    42301 tagaagtaga aatccgtcaa gtaccagcag ataaaaaagt ggatgtaaga gaagttttgt
    42361 aagaaaggaa gaacctcaat gattgtacaa gcagtcttat taggaattgt tgcatttgtc
    42421 gcacaatcag aatatgcact agggacatcg ttgctttctc gtccgattgt gacggggctg
    42481 tttacaggaa tcgtgttagg tgatgtaaaa actgggatca ttatgggcgc aactttagag
    42541 ttagcattta tcggatcgtt ctcagtaggt gcttcgattc cacctgatgt tgtgaccggt
    42601 gggattttag ggacggcttt tgctattaca gctggagccg gtacagaaac cgcgctttta
    42661 ctaggtttgc cgattgctac gttgacattg atattgaaaa atatttactt agggcttttg
    42721 attccaatta tgaaccataa agcagacaat tatgcagaag aaggaaatta taaaggagtc
    42781 gagcatatgc acttgcttgc cggtatcggt ctttccttga tgcttggtgt tgtggtaatg
    42841 gtttcttata tggtgggaag caatacgatc ggaaatctat taaatatgat tcctgacttc
    42901 gttcaaaagg ggttgtcagt agctacaggg ttgattccag ctcttggttt tgcgatgctt
    42961 gctcgtttgc tgatcaacaa acaagttgca ccatattttt tcttaggttt tgctatagct
    43021 tcttacttag agattcctgt gaccggagta gctatttttg gtgcgatttt agcagttgtg
    43081 gtagtcaata ttatgaatgt ccgtcaacta ccacttcaaa caactgcagg ggaggtagaa
    43141 gaagatgaag aattctgaga tcaaaaacag caaaataacg aaaaaagagc taaatcacgt
    43201 attttggcgt tcttttcaaa tggagttttc ttggaattat gaacgtcaga tgaatatggc
    43261 ttatgtttat gcaatgattc cgattttgaa aaagttatat cagtcgaaag aagaaatggc
    43321 agcagctttg aaacggcatc tagagttttt taacacgacc ccacatatcg ttacactgat
    43381 tttaggaatc acggctgcaa tggaggaaga aaataaggat gatcctgaat ttgatgtgac
    43441 tgcgatcgat agtatcaaaa catctttgat gggacctctt gcagggttag gagattcttt
    43501 cttttgggga actttgcgat tgattgccac aggtgtgggt acctctttag ccatgcaagg
    43561 aaatatttta ggccctatct tgttcatttt gattttcaat attccgcaca ttctgtttcg
    43621 ctatctagca acaggttggg gatatcgctt aggaacgggt tttttgaaaa agatccaggc
    43681 aaacggtatg atggaaagtt tgacattagg cgcgtctatt attggactga tggtcgttgg
    43741 agcaatgact gccacgatga tcaccatcaa tattccttta aaaatcggtt caggagaaaa
    43801 tgctgtgact gttcaaagta tttttgatga tatcgttcca aatatcttat gtcttggagc
    43861 atttggcata gtgttttatc tattgaagaa agaagtgaaa ccattaacga tcttgatcgg
    43921 actagctttc tttggaattt ttggttcgtg gatagggatt ttttaaaaaa ggagcagaga
    43981 aaatgtttac gatgcaagat tatatctatg aagaaaagga agtactaagt acgatcttga
    44041 aaaagaatga tttttcgaca agagaacata tgaaaaaaac agtgaattta ctgatcttag
    44101 caacgggttc atcttataac gcttgtttag cagcgaagcc agcattggaa tcttatggtg
    44161 atcttactgt cgatattcaa gaaccttttt attttttcaa ttatggaaaa ctttctcctt
    44221 caatcgatac tgtgattgct gtgtcacaaa gcgggaaaag tgcttctact gttgaagcag
    44281 taaaaatgat acaaaaacaa gggttacctg ttgttgctat cacaaatgac gtgcaaagtc
    44341 cacttgcttt agaagctgca caaattattg atttaggtgc cggggtagaa tcagtaggct
    44401 tcgttacaaa aggctattct gcgactgttt tacagttact actcttaggg ataggaattg
    44461 gaataagtaa aaataaaatc agcaaaaaaa tagaacaaga ctacatgcaa cagttgcgca
    44521 aaataatcaa ccatttacca gcgattattc aaaaaacgga agaatttttt gatggatatc
    44581 aaagtttatt tcgtttagca cagcgtttcg tcaccattgg atatggtcca aactggggaa
    44641 cagctaaaga agcagagacg aaattgactg aaacaatccg cgttccgtca caaggatttg
    44701 agttagaagc ttatatgcac ggcccatacc tggaggcaga tgcttcgcat ttgctattct
    44761 ttattgaagg ggaaagtgta aataaggaac gttcgcaaaa gttgcaaaga tatatgagtc
    44821 ggtacgttgg agagactctc accattacca caaaaaaagc aagaaacgag aaaacacttg
    44881 gattagcaat agaatgtgat gaatatctgt ctgtattagc gcttgtcgtt ccgtttcaac
    44941 tattcgctta taaaaccgca gtagctaaag gtattgactt gaacaaaaag atttttgaag
    45001 actttgatac agtcttgaaa agtaaattat aagaggtgga aatcatgctg aaattcaatg
    45061 aagaagaaca aatcaaagca ataaaaggcg cactagcttt acgtccgcaa gtagaagaaa
    45121 tcatcgataa actttatgcg gaaaaatttg acgctgtcta ttatctagga atcggtggaa
    45181 cgtatgcttc ctcgatgcaa gctgtcactt atatgaatgg gaaaagcaac ttgcctgtct
    45241 ttgtacagca tgctgcagaa tattacacta ctggaaacaa aagattaaca aaagattcta
    45301 tcgttatttt gtcctctgtt accggtacaa ctcaagaagt agtgaaagca gtagaacaaa
    45361 tcaagaaagt aggagcgaca ctgattggat ttatcgataa agcgaacagt aagttgtctc
    45421 agctatgcga ttttgtggtc acttatccag ctcctggaac agaacaaatc aaatttttta
    45481 tggcagcaga tcgattgatg tatttgaatg gagaattcga agcttattca gaatactatg
    45541 aacagctcga acgttattta ccaacagggt tagtggaagc agagaaaaaa gcagatgcat
    45601 ttggcttatc atttgcagaa aaacatcgac gtgatagtat gcattatttt attggagcag
    45661 ggaatcaatg gggagctgtt tattcatatg ccatgtgtta ctgggaagaa caaagctggc
    45721 ttccatcgaa atctatccat gctgccgagt ttcttcacgg gacgttagag atcgtagaag
    45781 aaacaacccc agtcacatta tttttaggcg aagatgaaca gagagtgtta tctgaacgtg
    45841 tggctaaact tttgccaaaa atttgcagca attatacatt gatagacaca aaagactatc
    45901 cagtagaagg tatcagtgaa aaatatcgcg gacgtgtttt gtctttctta ttgatgcatg
    45961 tagtgacaca acgcatcgat gctcatgtgg agcagttgaa ctgccatcca ttagagatac
    46021 gccgctacta tcgtcagttt gattattagg atagactgga taaaaagaat ataaaaaata
    46081 aagagagcag cgataactgc tccctttatt tttttaaaat attggcatca attacgttat
    46141 aaaacacatt tt
//
LOCUS       DAFBVQ010000014        42886 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.014, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000014 DAFBVQ010000000
VERSION     DAFBVQ010000014.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42886)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42886)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42886
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.014"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            6..305
                     /locus_tag="LLC22_000992"
     CDS             6..305
                     /locus_tag="LLC22_000992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5434286.1"
                     /translation="MKNRLIVACGSGVATSQTIASKIQSMLEDDGIAFPVEAVDYKSI
                     QNELLTAGIYVYVAQPDEEVLEQAKDLGIEVFPGIPFLTGMGVEPIYDSIKELVQ"
     gene            378..1739
                     /locus_tag="LLC22_000993"
     CDS             378..1739
                     /locus_tag="LLC22_000993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBK5434287.1"
                     /translation="MEVFQTIINYVLNLGSAIFVPLIILILGLLAGMKLKKAFMSALT
                     LGIAFSGMSMVIGYMSNAVSPASEALAKNTGISLPALDLGWTGAASITWSWSYAFIFF
                     AVTIGVNFVLLLFNWTKTLNVDMWNVWGKALTAYLVYYVSGSLAAGFLTAMVQVILEL
                     KLGDMFQKHIQDLTGIPLVTVTHFMTSAAVLLLPFNMIMDKIPALNKRADTNALKKKI
                     GIFSENSVMGFIIGLGLGFAAAYGVSGSLNLAIQTATALSLFPMISKMFMQSLSPLAD
                     AMSEFMKKRFKDREVYIGLDWPILAGRSEIWVTAILLVPVFIGYAIILPGNQVLPLAG
                     IINYSIAVGGLLLTGGNLARMLILGIITMPIYLYGATYLAPILSDLAEKSGAVEGIKK
                     GQLITWSSIEGPEFRVLFAEAFNRNILAIVGCVIFLGLFVLLYKYMIKAKVPSERYAE
                     LQK"
     gene            1761..2021
                     /locus_tag="LLC22_000994"
     CDS             1761..2021
                     /locus_tag="LLC22_000994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434288.1"
                     /translation="MKREETDKIKWTVALCGTLLLFLYGLFTQNIIINLLVIFFALVI
                     YKYGNHVLFREYDEKRKRKIEESMKIKEATKEILREKSFIKR"
     gene            2035..2787
                     /locus_tag="LLC22_000995"
     CDS             2035..2787
                     /locus_tag="LLC22_000995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II aldolase/adducin family protein"
                     /protein_id="HBK5434289.1"
                     /translation="MSDGRMLFERERQDMARIVRVIFERKNTNVAGGNFSFKTTDDQG
                     KDYIIMTPTMMSEAYLGEISPAQVLVVEPRTRRIVDGVGHLTREINMHEAMYETNPAI
                     KAVLHAHAPNAMFWATTGLPMPNLTEATAKVKEIPVMDFEPNCSEELAELTSDYVKKQ
                     HLELPHMLLLNSHGVLINTGGESGIEAIHKALQILDTVEWNAEIAYKQTIFQALGITD
                     GFYSKGEKIGGLEELKHKTAIYNKSVIAAGGD"
     gene            complement(2881..3486)
                     /locus_tag="LLC22_000996"
     CDS             complement(2881..3486)
                     /locus_tag="LLC22_000996"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5434290.1"
                     /translation="MTYIFEKGTSGKHLILLHGTGGDEHSLLDIAHFLAPNSTLLSFR
                     GTVQEDGMNRFFKRNGLNQFDLDSLEKETDKLHEKIKEISEKELIPLSDWLLVGYSNG
                     ANIAAHLLLERETELNKGLFFHPMSLGVHQSRSTLEDKTVWISYGDNDPIVSPASFKE
                     LADQFETRQANVTIQLTVTGHQLTMDEIKQAREWTDHLLTK"
     gene            complement(3539..4513)
                     /locus_tag="LLC22_000997"
     CDS             complement(3539..4513)
                     /locus_tag="LLC22_000997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ring-cleaving dioxygenase"
                     /protein_id="HBK5434291.1"
                     /translation="MDTQIRGIHHVTAMTSSATKIYRFFTDILGMRLIKKTVNQDDIE
                     TYHLYFTDDTGAPGTDMTFFDFPNQPKGKKGTDTISRASFRVPSDAALDFWLERFEKY
                     DVTHSAINERFGKKYIEFEDFDNQYYQLISDENNQGVAAGIPWKNSNVPTEFAITGLG
                     PVFVRVSQLEHIRLILEKILGFKETDHSGDFYLFEIGEGGNGASIIIEHRTDLPKAIE
                     GFGNIHHLALRVADKEALEYWIQVINKIELPNSGFVDRFYFQSEYFLAAHHVLFELAT
                     DGPGFLEDEPAESAGEKLSLPPFLEERREAIEAYVRPFDTSDANKKRE"
     gene            complement(4891..5610)
                     /locus_tag="LLC22_000998"
     CDS             complement(4891..5610)
                     /locus_tag="LLC22_000998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5434292.1"
                     /translation="MPKYEEIANILRERIRSKEYPLDSFLPNQVDLVKEFGASRMTIK
                     KAINILAMEGLVYSQRGSGTKILNHPFMQKDTSPANEYEGLSLQMKRRHRSLKSQIIH
                     FDVEFPNQYIQERLMIDAEQPVYNIHRLRILDGEPYVLEHTFMPVHLVPGLKKEHLLA
                     SIYDHLHQELNVHFAGAYRAISADKSDEYDQQYLNCAENDPVLEVQQVVYLKDGQPIE
                     YSSSRNRFDVRNYSVLDVRST"
     gene            complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LLC22_000999"
     CDS             complement(5737..7008)
                     /gene="celB"
                     /locus_tag="LLC22_000999"
                     /EC_number="2.7.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS cellobiose transporter subunit IIC"
                     /protein_id="HBK5434293.1"
                     /translation="MNGFMDKLSEKIMPLANLLGQNRYLTVLRDAFMLSFPLTMFGSI
                     VVVINNLPFFSDATKGTLSNLFGNGQNATMSIMSVFVTFGIGYYLSKSYDVEGIFGGA
                     VSFASFLILTPFAMKTAGGEDVTGVLSLDRLGAKGMFIGMIAAFLAGEIYCRITKRGW
                     QIKMPDGVPPAVTKSFAALIPAVVTLTIFLVINAVMTGIFNANLHDVVYEVIQKPLTG
                     LGSSLPATLIALFFVQFLWFFGLHGQIIVNSVMDPIWNTLMLDNLEAYQHGKELPHII
                     TKPFMETFTVGIGGSGMTLAVVLLMAFVLKKKQYRDVGRLALAPGIFNVNEPAIFGLP
                     IVLNATILIPWVVAPLIVTTFNYLVMAAGLVPAPTGVSVPWTVPIIASGVLATNSWLG
                     GMLQVIDFVIVAFIWYPFLKVLDKQPDLDIA"
     gene            7161..8558
                     /locus_tag="LLC22_001000"
     CDS             7161..8558
                     /locus_tag="LLC22_001000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5434294.1"
                     /translation="MKTYTFPENFWWGSAASGPQTEGRVSDDGKGENIWDHWYELEPE
                     KFFDQVGPEKTSQVYTKYKEDVQLMKETGHNTFRTSIQWSHLIPEGTGEINQKAVSFY
                     RDYFTELLDNGIEPFVNLYHFDMPLPLQEKGGWLSRETVDAYVSYAAACFELFGDLVK
                     KWFTHNEPIVPVEGGYLYQFHYPNHINMKEAVQVGYHENLASAKVIKAYHEGGHDGEI
                     GIILNLTPSYPRDETNPEDVKAAKIADAFFNRSFLDPAVKGEFPQELIEIVKELAIMP
                     EIHEGDLELIRENTIDLLGINYYQPRRIKAKETPINHEHSPMPDDYFDNYDMPNKKMN
                     PYRGWEIYEKGIYDILTNTRENYGNIKCYISENGMGVEGEERFVNSEGIIEDDYRIEF
                     VTDHLKYVHQAIQEGTNCVGYHMWTCMDNWSWTNAYKNRYGFIAVDLAQDGKRTIKKS
                     GRWFKTVSEKNGFDA"
     gene            8639..9079
                     /locus_tag="LLC22_001001"
     CDS             8639..9079
                     /locus_tag="LLC22_001001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5434295.1"
                     /translation="MVDTYRNILVAIDGSEKAEKAFLEAITIAKRNQATLHILYVNEV
                     TGNYFGDFAFVTTSLQEELDEVAENQMKEHRNLAIEKGLTDIETYVLYGYPKTLIANF
                     HESKEPIDLIVMGATGLNAVERALVGSTTSYVVNHASCNVMVVK"
     gene            9227..9553
                     /locus_tag="LLC22_001002"
     CDS             9227..9553
                     /locus_tag="LLC22_001002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5434296.1"
                     /translation="MISSDGIRGYNDAIILSILNKNDSYGYEISKTIRERTNDSYVIK
                     ETTLYSVFARLEKNQLIVSYPGEVTHGKKRTYYKITEIGRNLLEEKKQEWLTTKDVVD
                     QFLEGN"
     gene            9554..10303
                     /locus_tag="LLC22_001003"
     CDS             9554..10303
                     /locus_tag="LLC22_001003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434297.1"
                     /translation="MDTIRNYLDSLFIGVPQSTEIDKLKTDLLANMEDHYHELMGEGK
                     NEQEAIGTVISTFGSIDELLEELDVEKKHQADETETNTASIYLSEAENYWKEYRAASL
                     QVASGVLFISLSFASFLFFCSAGYVFMGISCLIFGIALAVGFFIASGMKITRLNHFLH
                     HRKIPEKVLAEAKEKEEEYQRSFGFSLIAGIGLCIFSLFPLLASLMWYMDGSIGASIF
                     FVTVGTGVFLIIYGSLVRHSYRQFTQSAYYW"
     gene            complement(10383..10838)
                     /locus_tag="LLC22_001004"
     CDS             complement(10383..10838)
                     /locus_tag="LLC22_001004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289471.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBK5434298.1"
                     /translation="MLTIYSSRTHSYHLMANWLKDHQMPYRERIFTPKQPLTRKEIFY
                     LLSLTENGFDDLLAKRSIDYKNLKDQIDQCTTSELVDLIVSHFTLLQRPIITDGKKLL
                     VGFNEDSMRLFIPVQWRRSQLKSVYNDFTWVSNLENSTDLDDEFLNYYI"
     gene            complement(11265..11540)
                     /locus_tag="LLC22_001005"
     CDS             complement(11265..11540)
                     /locus_tag="LLC22_001005"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434299.1"
                     /translation="MKLEDKKVILKKIKRLPDQIDGYTICSFKKDRSIKAYTQNTEKG
                     IIYFLHEEGYDTQTFMFTEKKEFHKQMKKLIEKEFPRSHKLYVNQQF"
     gene            11834..12649
                     /gene="thiD"
                     /locus_tag="LLC22_001006"
     CDS             11834..12649
                     /gene="thiD"
                     /locus_tag="LLC22_001006"
                     /EC_number="2.7.1.49"
                     /EC_number="2.7.4.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional hydroxymethylpyrimidine
                     kinase/phosphomethylpyrimidine kinase"
                     /protein_id="HBK5434300.1"
                     /translation="MEDQYVQAMTIAGSDSDGSAGMQADMHTFFTRNVYGVSVMTACV
                     AGNSYGIGASVTLPTDFIDKEFELIAKDFQIRAAKTGMLADSKLIETVVKNYQKYDFG
                     PLVVDPVIVTKHGNLLLEESALQSLKEKLVPLAEVLTPNFYEAEKLTGRTLAAEEDFV
                     QAAKELQDMGAKNVMIKGHHAKNAQQETVNDYVLFESGKSFWLNAPFYPTDRINGTGD
                     SLSACIAAELAKGKTVEQAIRLAKDYVNRAIREEINVGHKYGPINHWAAGELE"
     gene            complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LLC22_001007"
     CDS             complement(12978..14429)
                     /gene="cls"
                     /locus_tag="LLC22_001007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBK5434301.1"
                     /translation="MVSSIITALYLLNALIALVAILIKPRDVAAIWAWLLVLFALPGV
                     GFVLYLFFGRGLTDKKKFYLRQSDLKELENFQSFRGDTIEHYDPDMGDKDKQQFVDFF
                     SSLNRMPLTRMNSVTLLTDGQEKLDSLLQDLKKAKHSIHIEYYAFVTDNIGQQVLHVL
                     EEKAAEGVEVRILYDAFGSHGTKAKDFNRLIKNGGHVHTFVTSQRALLRFRLNYHDHR
                     KIVVIDGKISYTGGFNIANQYVNTTKKFGYWRDTHIRIFGAASSLLQLRFLTDWNVSV
                     PEEKKVGYHLNYFFKKADRDESKLADTSIQLVSSGPNNEREQIKLSFIKLITSAKKRV
                     WIQTPYLVPDESVIAALKIATASGVDVKIMIPNKPDHPFIYRATQYYARQLIKENVQI
                     LVYENGFLHAKTLIMDDEICMVGSANQDIRSYRLNFETSAVIYDPEFLEELATQFKED
                     ETHCSSMTTETVKEMSNWLLFKQQISRLFSPIL"
     gene            14770..17436
                     /locus_tag="LLC22_001008"
     CDS             14770..17436
                     /locus_tag="LLC22_001008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331875.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5434302.1"
                     /translation="MENKEQAQQAVYKETIDSLMQQTQSSTDGLSTTQAKEKLERDGL
                     NQLKEKPKKPTWKLFLETFKDAMVIVLLIVALIQMVMGDYIEFLVIFAVLMLNSIISV
                     VQTKKAEGSLEALKNLSAPDARVIRDGKEKTIPANELVVGDIVLLDAGDYVPADGRLL
                     DAGSLKVDEGMLTGESTSAEKEVTDITSTVPIGDRTNMVFSGTIVTYGRGKFLVTSTG
                     NNTEIGQVAGLLESTTEQVTPLQRGLDKFSKKLSLAILALSLLILGIQLFRIYLGEGT
                     GDMTADIVSAVMFAVAVAVAAIPEALQSIVTIVLSLGTNKMAKRHAIIRKLPAVETLG
                     STSIICTDKTGTLTQNKMTVVDYFLGNGDTGDFTNDPSKWTADERRLIEISVLANDAS
                     ISEDGTKLGDPTEVAFIDFSEKLNQPYQEIRNNYPRQAELPFDSDRKLMSTGHTIDNK
                     NYLFVKGGPDIVFQRSKKVLLNGEVVPMTDELMKKFQEQNEAFSTRALRVLAFAYRPL
                     DNFDLSFEDEDDLILVGLLAMIDPPRAEVTQAVTEARSAGIKTIMITGDHKTTAVAIA
                     KQIGIFEEGNLALTGTELDELTEDQLNEVLEKVTVYARVSPENKIRIVRAWQNKGHIS
                     AMTGDGVNDAPALKQADIGIAMGTGTDVAKDAAAMVLTDDNFASIVSAVEVGRNVFDN
                     IKKAISYLFAGNLGAIIAIIFALVADWSNPFTALQLLFINLVNDSLPAIALGTEKAEP
                     ATMNRPPRDPNSGIFTDKTLISVTYRGVLIGIAVIFAQWLGMQHSPEFGVAMSFSTLI
                     WCRTLQTFPARSNTQTAIQAGFFSNRSVLLAVVVCSALYCLTMIPGLKEVFSIPSAFG
                     LTEVFTCMGIALVTIVLMEITKLIIVRVQGNK"
     gene            17800..18552
                     /locus_tag="LLC22_001009"
     CDS             17800..18552
                     /locus_tag="LLC22_001009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629622.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5434303.1"
                     /translation="MNEKEWDEFAEEYYEIQQESQVTIAEDVKNYLKTEKVLPAETAA
                     DVAGGSGRFLSLAKEINRYDLIDFSSGMLENAKKEAEKNELPNVSFIKQSLEEFIQSN
                     ETYEMVFTAANPALVHLIQLEKLMKKSSKWCVIIRVVESIDDVFYPIEKQLGMIEEDP
                     NTSPVVMDQFETYLIDEGFKVKKKDFTYFTQESITEELMKLYYDAYAKDPVVTRYIRK
                     LFSEKREILSTTKLTYRLLLWSADKKRTFHDS"
     gene            complement(18574..19728)
                     /locus_tag="LLC22_001010"
     CDS             complement(18574..19728)
                     /locus_tag="LLC22_001010"
                     /EC_number="2.3.3.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335590.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA synthase"
                     /protein_id="HBK5434304.1"
                     /translation="MKIGIDRLSFFIPNLYLDMTELAESRGDDPAKYHIGIGQDQMAV
                     NRANEDIITLGANAASKIVTEKDRELIDMVIVGTESGIDHSKASAVIIHHLLKIQSFA
                     RSFEVKEACYGGTAALHMAKEYVKNHPERKVLVIASDIARYGLASGGEVTQGVGAVAM
                     MITQNPRILSIEDDSVFLTEDIYDFWRPDYSEFPVVDGPLSNSTYIESFQKVWNRHKE
                     LSGRGLEDYQAIAFHIPYTKMGKKALQSVLDQTDEENQERLMARYEESIRYSRRIGNL
                     YTGSLYLGLTSLLENSKSLQPGDRIGLFSYGSGAVSEFFTGYLEENYQEYLFAQSHQE
                     MLDSRTRITVDEYETIFSETLPEHGECAEYTSDVPFSITKIENDIRYYKI"
     gene            19913..22354
                     /locus_tag="LLC22_001011"
     CDS             19913..22354
                     /locus_tag="LLC22_001011"
                     /EC_number="1.1.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylglutaryl-CoA reductase,
                     degradative"
                     /protein_id="HBK5434305.1"
                     /translation="MKEVVMIDAARTPIGKYRGSLSPFTAVELGTLVTKGLLDKTKLK
                     KDKIDQVIFGNVLQAGNGQNVARQIALNSGLPVDVPAMTINEVCGSGMKAVILARQLI
                     QLGEAELVIAGGTESMSQAPMLKQYQSETNEYGEPISSMVNDGLTDAFSNAHMGLTAE
                     NVATQFSVSREEQDRYALSSQLKAAHAVEAGVFSEEIIPVKISDEDVLSEDEAVRGNS
                     TLEKLGTLRTVFSEEGTVTAGNASPLNDGASVVILASKEYAENNNLPYLATIKEVAEV
                     GIDPSIMGIAPIKAIQKLTDRSGMNLSTIDLFEINEAFAASSIVVSQELQLDEEKVNI
                     YGGAIALGHPIGASGARILTTLAYGLLREQKRYGIASLCIGGGLGLAVLLEANMEQTH
                     KDVQKKKFYQLTPSERRSQLIEKNVLTQETALIFQEQTLSEELSDHMIENQVSEVEIP
                     MGIAQNFQINGKKKWIPMATEEPSVIAAASNGAKICGNICAETPQRLMRGQIVLSGKS
                     EYQAVINAVNHRKEELILCANESYPSIVKRGGGVQDISTREFMGSFHAYLSIDFLVDV
                     KDAMGANMINSILESVANKLREWFPEEEILFSILSNFATESLASACCEIPFERLGRNK
                     EIGEQIAKKIQQAGEYAKLDPYRAATHNKGIMNGIEAVVAATGNDTRAVSASIHAYAA
                     RNGLYQGLTDWQIKGDKLVGKLTVPLAVATVGGASNILPKAKASLAMLDIDSAKELAQ
                     VIAAVGLAQNLAALRALVTEGIQKGHMGLQARSLAISIGAIGEEIEQVAKKLREAEKM
                     NQQTAIQILEKIREK"
     gene            complement(22684..23388)
                     /locus_tag="LLC22_001012"
     CDS             complement(22684..23388)
                     /locus_tag="LLC22_001012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434306.1"
                     /translation="MKKKQKQKLLNQFRPSLDGVRGQLFRSLEEESLRRYGLPLQVML
                     DPKNRQILTIGLAGKTNEDTRINVPIDDNFNTVLKRIRSGENGIFERFRDNLLIEIVS
                     YWNDQRLKNDEPTAQAVATPVTEETVSVPEEKTEKPKADTTENTRSTDTNAALSFADF
                     SKAVAEYPKFYTEQNEHEVVINEKNADEPRKLATISMTTENEFVIEKALERKYKVKLT
                     LIPLIEQFAATAITDR"
     gene            complement(23575..23820)
                     /locus_tag="LLC22_001013"
     CDS             complement(23575..23820)
                     /locus_tag="LLC22_001013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434307.1"
                     /translation="MDPIERLNSLSEEVTQTFHSDFVFLIDAEKIQHFPARNWTHDQI
                     IEELKKRFDHSLMVKPWHEHEVIYSPELPVFALIPKK"
     gene            complement(23837..24688)
                     /locus_tag="LLC22_001014"
     CDS             complement(23837..24688)
                     /locus_tag="LLC22_001014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldo/keto reductase"
                     /protein_id="HBK5434308.1"
                     /translation="MNSLTSTYRLSNGYEIPVVGFGTWQTPDGDVAVSSVKEALAAGY
                     RHIDTAQGYKNEESVGQAIKESGIPREEIFLTTKLWNANHSYELVMSSFEESLKKLQT
                     DYLDLFLIHWPNPVAFRDNWEQANADTWRAFEELYEAGKIKAIGVSNFLPHHLDTLAK
                     TAKIMPMVNQVFLAPGELQTTVVEYAKKHDMILEAYSPLGTGKIFDVPEMKQIAEAHD
                     KTIAQVALRWSLQHEFLPLPKSVTPSRIKENTELFDFELTEEEMKQIDQLDGVVGKAK
                     DPDTTQF"
     gene            24854..25858
                     /locus_tag="LLC22_001015"
     CDS             24854..25858
                     /locus_tag="LLC22_001015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoid-associated protein"
                     /protein_id="HBK5434309.1"
                     /translation="MDIYLKKAILHIIDRETGSPVFSQKELDLTKEYIRDFLQKKIQK
                     ISSAQTKTGQLAEESMIVESLKIAQENFVEASEAIVQRWFDIYQESEEAPSADVFVVL
                     YELDTVMYLSLLKVNYREAYTHFVEADEAGIDNRLILNRAILGAKTQKADEAFAVNLT
                     DWTYELIEKKYEFSGKKELYFSGRVIESVPAPSLEENVKVIQKVAKHLGKKFETEEFD
                     IMADLKEAVYDTIEEKGRLDHEMIAEKVFKENITAKMAFKEEVQEQGFVPEAPPVKEV
                     QEISEKKFGKQKFKLSNGIELIVPVDVYRNPDLIEFVNNPDGTISVMIKNVDEVLNRL
                     "
     gene            complement(26099..26455)
                     /locus_tag="LLC22_001016"
     CDS             complement(26099..26455)
                     /locus_tag="LLC22_001016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5434310.1"
                     /translation="MKKLIGVLVVLGIFLGGSFAAYHYFYGGEAYYTKITTNGEMSAT
                     QADNGEKFTTYTYKQAAYNKDGEKKQVTLREEREHPLKMNAYLKLKVNPRKGVLSWEE
                     IKASEVPKNAAEKIDN"
     gene            26823..28010
                     /gene="tuf"
                     /locus_tag="LLC22_001017"
     CDS             26823..28010
                     /gene="tuf"
                     /locus_tag="LLC22_001017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Tu"
                     /protein_id="HBK5434311.1"
                     /translation="MAKEHYDRSKPHVNIGTIGHVDHGKTTLTAAITTVLGKKGLANP
                     QDYASIDAAPEERERGITINTAHVEYETEKRHYAHIDAPGHADYVKNMITGAAQMDGA
                     ILVVSATDGPMPQTREHILLSRQVGVKYLIVFLNKVDLVDDEELIDLVEMEVRELLSE
                     YGFPGDDTPVIKGSALKALQGDPDAEAAIMELMDTVDEYIPTPERDTDKPLLLPVEDV
                     FSITGRGTVASGRIDRGAVRVGDEVEIVGIKPETQKAVVTGVEMFRKTLDYGEAGDNV
                     GVLLRGIQRDDIERGQVLAKPGSITPHTKFKAEVYVLTKEEGGRHTPFFNNYRPQFYF
                     RTTDVTGTITLPEDTEMVMPGDNVTIDVDLIHPIAVENGTTFSIREGGRTVGSGIVTE
                     IEA"
     gene            complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LLC22_001018"
     CDS             complement(28198..30789)
                     /gene="mprF"
                     /locus_tag="LLC22_001018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysylphosphatidylglycerol
                     flippase/synthetase MprF"
                     /protein_id="HBK5434312.1"
                     /translation="MLKNTIQWLKNHLGLFKTIFLISVIVIIVGELMSIGKTLSIQQL
                     GETFATIPVWKSGLMLLIGLISVLPMVGYDIILNRMLEQKQNPRYLFETSWLINTINN
                     IAGFGGFVSVGLRSELYGQKKESRNVIQALSKVFLFLMAGLSIYSLLSFLLVVFTPVA
                     PFLKQYWIWLIGGGLYFPVVFLFTTFKKKGFLGGTSLKTQGQLLLVSLLEWTGVLFSF
                     LSVGYLMEIRIDLWQTIPLFIAASVIGIVSMIPGEIGSFDVMMIIGLSAIGVPREIVV
                     VWILLYRLFYYIIPFLIGIVFFFKNIGSTFDQRYSGIPKQLATEIAHKIVVVLLYFSG
                     IMLVLSATIPQAFTEFRWLHSLNPLKFHFIIQFPSILLGFLLIIMGRGIAARVKRAYL
                     PTIFLIVLALLYVLLSDFSFTPVVFLSILLLIILASKNELFREQLIYSWEWRTIDGII
                     IGALSLLYIVIGVYNLPDFPHRRHHFISFFLFPSEKIWFSGLLAIIAVSFMIVLFVHF
                     LQGEKKQIGEAFNEEKALKILTTYGGNSDSQLIFLKDKRMFAYEKDGEPTVLLQFACF
                     NNKCIVMGDPSGKKEDFPEAIEAFIEETDRLCYLPVFYETSEEIVMILHEFGYDFIKM
                     GEEAYVDLNSFTTSGKKMKGTRAVLNRIEREGFTFDVLQPPFSTEQMSTFKNISDNWL
                     GSRKEKGFSLGFFSEDYLQRAPIAVVKNTQEEIVAFATIMPTYTNNKVGTIDLMRYDS
                     KKAPSGSMDFLFLHLFAYMKEEHIQWFNLGMAPLSNVGTSRKSFLQERIAYLVYEFGS
                     HFYSFHGLREYKSKYATNWVSRYTLYSRDSWIAYVMIALLIIDNAPVEQTQGRISGLK
                     KWIRRKY"
     gene            complement(30815..31576)
                     /locus_tag="LLC22_001019"
     CDS             complement(30815..31576)
                     /locus_tag="LLC22_001019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5434313.1"
                     /translation="MTDIIVILYTVGDYVKKEKKYAKMPDGSEIYYEKSGQGFPLFLL
                     HGNDGSGRFFSEQVPVLERYYTVYLVDSRGHGRSTNEASMLNFQLMAEDLNTIMLLEK
                     IDQADFLGFSDGANLALVFASSFPKKVHRLILNSGNTLVKGVRFSARVISNIHYAWVW
                     LLSLFRPSLRKNLLVIKLLLHDIGLTENDLKKINSPTLIIVGKKDVIKLKHSLYIAKT
                     IPKASFVLVKEQGHELARKDPERFNREVLQFLSET"
     gene            31854..32375
                     /locus_tag="LLC22_001020"
     CDS             31854..32375
                     /locus_tag="LLC22_001020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lysozyme family protein"
                     /protein_id="HBK5434314.1"
                     /translation="MESYQIEITTAAKNYHMENYENLIKAIILTESKGKGTDLMQSSE
                     SLHGEAEIIDNPADSIDQGVKYLAEMIVEAKKQGCDLWTAVQAYNFGKDYIAYVKNHG
                     GENTVELAEAYSKDVLSPLLGNEEGKQYRYWRIQSLLYNGGYLYHNGGNMFYPDIVKM
                     NEKIIETYEKVFK"
     gene            32434..33294
                     /locus_tag="LLC22_001021"
     CDS             32434..33294
                     /locus_tag="LLC22_001021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF368 domain-containing protein"
                     /protein_id="HBK5434315.1"
                     /translation="MEKRQKMENQEVGYTTKDWMLRFVKGMFIGSGFILPGVSGGALA
                     AVFGMYERLISFLAHLTKNFKENVLFFLPVGLGGVTGIFLLSFLVSFLLGAYETTILW
                     FFVGCIAGTVPALWKEAGKKGRDTSDVIIMVVTFVLAYLFLLYGAQLFDGQVDQNFGT
                     WLIAGGLIGLGMIVPGLSPSNFLVYMGLYKAMADGFKEVRLEVIVPIGIGGILCVLGL
                     SKIMDYIFSKAYSKLFHFILGVVFASTIMIIPTDYAGLGVAGVLACPVLFIAGTALGW
                     WMSRLEEQYK"
     gene            33479..35794
                     /locus_tag="LLC22_001022"
     CDS             33479..35794
                     /locus_tag="LLC22_001022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5434316.1"
                     /translation="MNGLTQQEVVQKMASGQQNDYQEDASKSTKQIFSDNILTLFNFL
                     NFGIGICLLFVGAYSNMAYLAIIVVNIVIGIYQEIHARNLVRKLSIVSQSEVLVIRDG
                     KEQSISTKELVLGDLVKIGAGEQIPADLQVISGRAEANEALLTGESDLIVKETGAELL
                     SGSFLTSGSVMAEVIRVGADNYAVRLTSEAKTHKAIRSELVDSIRKVSKFTSFVIIPL
                     GIILFLEALFIRDASIKISVIASAAALLGMLPKGLVLLISIALTTGVTKLAKKRILVQ
                     DMYSIETLAHVDTLCLDKTGTITEGKMSIQRVEALHPLYEKAIPEIMGTYLAESSDNN
                     ITMRAMRDYFELSNRYDVTNKVAFSSDRKWGAMEFPELGVVYVGAPERLVEEDRLPDS
                     LKTAQANGYRVLMLGIAPNQQLNEEKPAFVEPVALFEIDDPIRKNAQETLAYLHEEGV
                     DLKVISGDNPFTVSNIARRAGLPNYDAYVDLSQITEEMEVREAAHRYTVFGRVSPQQK
                     KLLVNELKESGRTVAMTGDGVNDVLALREADCSIAMAEGDGATRQIANLVLLDSDFTT
                     LPEVLFEGRRVVNNVTKVSGIFFIKTIYSFILSIICAVTAIGFPFIPIQITLIDLAIE
                     GYPSFFLSFEQDKRKITYRYLPTALINALPNALLVVVNIIAVYLLGKTFAWGNAETTT
                     LMYYLLIGISCMAVVKACYPFNPLRIFLAVTTIVGIYVAAMLFHGILEVNLGLGESVG
                     YFFVFMLVNIVLRVLYWKADIQNQLLKRVAN"
     gene            35976..37817
                     /locus_tag="LLC22_001023"
     CDS             35976..37817
                     /locus_tag="LLC22_001023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337760.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA primase"
                     /protein_id="HBK5434317.1"
                     /translation="MAQRIPQEVIETVRSQTNIVEVIGQYVQLKKSGKNYLGLCPFHE
                     ERTPSFSVAEDKQIFHCFGCGKGGNVFTFLQELEGLSFPEAVVKVADFEQIPLEDQWR
                     QRTIAVQNPESATGKLIAAHEKAAEIYHHMLLHTKAGQPALEYLQSRGLSLELIEEFN
                     IGFAPNERSFLQQVFKNESISNELLERSGLFVTHDDGRMSDRFYQRVMFPLRNSQGQT
                     IGFSGRWLAPEKGQEKDQPKYLNSPETELFNKRQVLFNLDKARSDIRKNGEILLFEGF
                     MDVIAAWQAGIKTGLASMGTSLTAQQIQQMEKLTKELVFCYDGDNAGFEATNRGIELL
                     RQNSRLALSVVVVPEKLDPDEYLRKYGEASFQELVAHGRETVFTFKSRYLKQGKNLDN
                     EKDKIEYLEELLVELSRVVSPIEQDMYLSQLSTEFQIGRETIQKQLRDLRRTNQQNRQ
                     EPQESQHTQVTRQETARKKRPLTQVEKAEQILLYRAFKEVSVRNILKEREFQFIHDAY
                     AEVYFLFDAYVSQHYEFNLAEFLDFLQDENLRRLVVEIEYLPVAEESSPREIQDLLDV
                     ISKSGLADEITLKKQMQQEARRTGNKQLELELTIEIINLTKQLKQAK"
     gene            37841..38950
                     /gene="rpoD"
                     /locus_tag="LLC22_001024"
     CDS             37841..38950
                     /gene="rpoD"
                     /locus_tag="LLC22_001024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase sigma factor RpoD"
                     /protein_id="HBK5434318.1"
                     /translation="MANGTDKKTYEAAVAAFIKENKPKRQVVYDDLSNQLATPFTLNA
                     DEMDKLIQKIEDAGISVVDENGDPSIHSLKSAEKKAEQAKTEDLSAPTGVKINDPVRM
                     YLKEIGRVSLLTAEEEVALALKIEEGDQEAKQRLAEANLRLVVSIAKRYVGRGMQFLD
                     LIQEGNMGLMKAVEKFDYRKGFKFSTYATWWIRQAITRAIADQARTIRIPVHMVETIN
                     KLIRIQRQLLQDLGREPTPEEIGAEMDLPTEKVREILKIAQEPVSLETPIGEEDDSHL
                     GDFIEDQEATSPAEHAAYELLKEQLEDVLDTLTDREENVLRLRFGLDDGRTRTLEEVG
                     KVFGVTRERIRQIEAKALRKLRHPSRSKQLKDFLE"
     gene            39170..41269
                     /locus_tag="LLC22_001025"
     CDS             39170..41269
                     /locus_tag="LLC22_001025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBK5434319.1"
                     /translation="MKKCPNCGSKKMEQNTICPDCGHQITAEDQQIKESIEETNTDAA
                     MQDKSTEDAVFPDTELNDPIEWSELKDLPLESVMELFEKAEPEDEEPPAHDQVTNIEK
                     NEQKKATVHETSEESGKNQEETLESKQKRRVAELKEIVDNEEENSILSAYIKAHREDT
                     KEEHAKELLKMISEKIAQENKVEPEKEQETEKDSDRENATGKETVKIKDVKTDITEKT
                     EVFTEKQLEKEKTNKLPEAEKKEILENTDKKSTEPDEINSESDAENQSVSKEGTDLEA
                     KIEKEENQPKLFEAEAKSITIVPDTEKTHQESNLEKTDPDKAQKKKSKKVPYLVLAAV
                     LLLGGGSWAYYDHHQKVEAEVAAEAKRQQQMEELHEKLAAFYTDDHHQFIRADMIHQD
                     LSKLKNDLSSLKNEKGYSELETTYQDIQSKIRDIQKVNEWFIAPAIVDDHLADDIKLK
                     ADKEIQAIETDNTDFGKLIQQAQTEAKNQYAELQTAKEKTAIVFKDGKVVDSATRDQY
                     KTAKEAVEKVKNTDLSAQLNEQLKQVDKMLTDKEKKEEEEKKKAEEAKKAAEEQAKQA
                     AQAAAAAQAAQQAAVAQAAQQEAASSTPSSSNSANQPIKSARASDIADASNPAWTWAP
                     GVQSKVIATCIQRGYIVEGGYRLEKARIENGEGYYNLYATSTKSALMKGIGESALPFY
                     IVTINCKTGWFGGNGSN"
     gene            41465..42328
                     /locus_tag="LLC22_001026"
     CDS             41465..42328
                     /locus_tag="LLC22_001026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339421.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein"
                     /protein_id="HBK5434320.1"
                     /translation="MNDLLATIFTGIIIDENEKNYFVQKNGQTFGLSKSEGEHKIGEA
                     VEGFGYQNQKHENRITTQIPKSRIGHYAFGIVTATRKDLGAFVDIGLPDKDFVVSLDE
                     LPTMTELWPKKGDRLMISLRVDAKDRIWGSLADEKIFKSLSKYGTEEMKNKDVIGTAY
                     RLKLTGTYVLTEDFYLGFIHPSERYNEPRLGEQIKGRVIGVRPDGVLNLSLKPRAYEA
                     ISDDAQMILTILERSADQQINFTDKSDPEEIMKAFGISKGAFKRALGNLLKQGLITQE
                     NGVTKLVKKSN"
     gene            42433..>42886
                     /locus_tag="LLC22_001027"
     CDS             42433..>42886
                     /locus_tag="LLC22_001027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK5434321.1"
                     /translation="MVMNAISAMKKTKQQLHEAGFKLTPQREATLLVLLENEKEHLSA
                     EEIFFLVKKKSPEIGLATVYRTLEILTELKIVDKVSFNDGLARYDLRKEGAKHFHHHL
                     LCLNCGTIEEVEEDLLLEVEQVVEERYHFLVKDHRLTFHGICQECYEKE"
BASE COUNT        14096 a         7511 c         8868 g        12411 t
ORIGIN      
        1 aaaaaatgaa aaatcggtta attgtcgcat gtggaagtgg agtagcaacg agtcagacaa
       61 tcgctagtaa gatccaaagt atgttagaag atgacggcat cgcatttcct gtagaagcag
      121 ttgattacaa atcgattcaa aatgagcttc taactgctgg aatctatgtg tatgtcgcac
      181 aacctgatga ggaagtactt gaacaagcaa aagatttggg tattgaagta tttccaggaa
      241 ttccattttt aactggaatg ggtgtagaac ctatttatga cagtatcaaa gagttagtac
      301 agtaaaggag gattgttgga taaaaaagtt ggttcatagt tttatttact atatttagaa
      361 agaaagaagg tttatttatg gaagttttcc aaaccattat caattatgtt ttgaacttag
      421 gatcagccat ttttgttccc ctgattattt tgatacttgg attgttggca gggatgaaat
      481 taaaaaaagc attcatgtct gctttgactt tagggattgc ttttagcgga atgtctatgg
      541 tcattggcta tatgtctaac gcagtaagtc cagcatcaga agcattggct aaaaatacgg
      601 gaatcagttt gcctgcactt gatcttgggt ggacaggtgc agcaagcatc acatggtcgt
      661 ggagttatgc ttttatattt tttgcagtaa cgattggggt caattttgta ctgttacttt
      721 ttaattggac gaagacgtta aatgttgata tgtggaatgt ttgggggaaa gctttaactg
      781 cttatttagt ttattatgtt tccggtagtt tggctgcagg ctttcttact gcaatggtcc
      841 aagttatatt ggaattaaag cttggtgata tgtttcaaaa acatatacaa gatctcacag
      901 ggattccatt agtaacagtg actcatttta tgacatctgc cgctgtcttg ttgctgcctt
      961 tcaatatgat catggataaa attcctgctt taaataaacg agcggatacg aatgcattga
     1021 agaagaaaat tgggatcttc tctgaaaact ctgtaatggg attcattatt ggattggggc
     1081 ttggctttgc tgctgcgtat ggcgtttcag gttctcttaa tctagcgatc caaacagcta
     1141 cagcattaag tttgtttcct atgatctcta aaatgttcat gcaatctttg tctcctctag
     1201 cagacgctat gtcagaattt atgaaaaagc ggtttaagga tcgtgaagta tatatcggat
     1261 tggactggcc gatattagct ggtcgttcag aaatttgggt tactgctatt ttacttgttc
     1321 ctgtgtttat tggttatgcc attattttgc caggaaacca agtattgcca ttagcaggga
     1381 ttatcaacta ttcgattgcg gtcggcggat tacttttaac aggaggaaac ttggctcgta
     1441 tgctgatctt gggaatcatc actatgccta tttatttgta cggggccact taccttgcgc
     1501 caatactcag tgatttagca gaaaaaagcg gagcagtcga gggaatcaag aaaggacagt
     1561 tgatcacatg gtcatccata gaagggccgg agttcagggt tttatttgcg gaggcattta
     1621 ataggaatat tctcgctatt gtaggatgcg tgatttttct aggactgttt gttctacttt
     1681 ataaatatat gataaaagcg aaagtaccga gtgaacgtta tgctgaacta caaaaatagc
     1741 attgaaatgg tgggaaagta atgaaaagag aagagacaga taaaataaaa tggacagtcg
     1801 ctctttgtgg tacacttctg ctatttctat atggactctt tactcagaat atcatcatca
     1861 atctattggt catttttttc gcactagtga tctataaata tggaaatcac gttttattca
     1921 gagagtacga tgaaaaaaga aaacggaaaa tagaagaatc aatgaaaata aaagaagcta
     1981 ccaaagaaat attgagagaa aaaagtttta taaaaagata atggaggggt cattatgtca
     2041 gatggacgta tgttatttga gagagaacga caggacatgg cacgtatcgt aagagtgatt
     2101 ttcgaaagga aaaacacaaa tgtcgcagga gggaattttt cctttaaaac cactgatgat
     2161 caagggaaag actacatcat catgacgccg accatgatgt cagaagccta tctaggagag
     2221 atttctcctg cacaggttct agtagtagaa ccaagaacgc gtagaatcgt tgacggagtc
     2281 ggtcatttaa ctcgtgaaat caatatgcat gaagcgatgt atgagactaa tccagctatc
     2341 aaagctgtcc tacatgctca tgcgcctaat gcaatgttct gggcgactac tgggttgcct
     2401 atgcctaatt tgacagaagc cacagctaaa gtaaaagaga ttcctgtcat ggactttgag
     2461 cctaattgct ctgaagaact tgctgaattg acaagcgact atgtaaaaaa acagcatctc
     2521 gaattaccgc atatgttgct gctcaactct catggcgtat tgatcaacac aggtggagaa
     2581 tcaggaatcg aagctatcca taaagcactg caaatccttg atacagttga atggaatgca
     2641 gaaattgcct acaagcagac gatttttcaa gcattaggga ttactgacgg tttttattca
     2701 aaaggtgaga aaatcggggg attggaagag ttgaaacata aaacggctat ttataataaa
     2761 tctgttattg cagctggtgg agactaacct atctgacaca aaaaactacg actttcacaa
     2821 aatctgatcc agatcgatat ctgcttcagg ttgtattatg taagtcgtag ttcttttctt
     2881 ttatttagtt aagaggtggt ctgtccattc cctcgcttgc ttgatttcgt ccatcgtcaa
     2941 ctgatgacct gttacagtta gctgaatagt cacatttgct tggcgtgttt cgaattgatc
     3001 ggccaattct ttaaaggaag caggggaaac gattggatcg ttatcaccat aagaaatcca
     3061 gacggtttta tcctctaatg tggaacggct ttgatgaaca cctagagaca tcggatggaa
     3121 aaacaaccct ttatttagct cggtctcacg ctccaataat aaatgagcag cgatgtttgc
     3181 gccatttgaa tagccgacaa gcagccagtc acttaacggt atcagttctt tttcgctgat
     3241 ttctttgatt ttttcatgga gtttatctgt ttctttttcc aaactgtcca ggtcgaattg
     3301 attcaatcca ttacgcttga aaaaacgatt catcccatct tcttggaccg tgccacgaaa
     3361 agaaagcaat gtactgtttg gtgcaagaaa gtgagcgata tccagtaaag aatgttcatc
     3421 gccacctgtg ccatgaagta agatcaaatg cttgccactt gttccttttt caaaaatgta
     3481 ggtcattttg ttccctcttt tctgtttcta tagatgcaaa tgaagtagca tgaagagatt
     3541 attcacgttt tttatttgca tcacttgtat cgaaaggacg gacataagct tcaatggctt
     3601 cacgacgttc ttctaagaat ggaggaagag atagtttttc tcctgctgat tctgctggtt
     3661 catcttcaag gaatccagga ccatcagttg ctaattcaaa cagtacgtga tgagcggcta
     3721 ggaagtactc agattggaaa tagaaacgat cgacgaaacc agaatttggc aattcaatct
     3781 tattgattac ttgaatccag tattccaatg cttctttgtc tgctacacgc aatgctaagt
     3841 gatggatatt tccaaatcct tcgattgctt ttggcaagtc tgtccgatgt tcaataatga
     3901 tgcttgcacc atttccccct tcaccgattt caaataagta gaaatctcct gaatggtctg
     3961 tttctttgaa tcctaagatt ttttcaagaa tcaagcggat atgctctaat tgactgacac
     4021 ggacaaagac aggtccaagt cctgtgatcg caaactctgt cggtacattg ctgtttttcc
     4081 aaggaatgcc agctgctaca ccttgattgt tttcgtcaga gatcaattga taatactgat
     4141 tatcgaaatc ttcaaattcg atatattttt tgccgaaacg ttcattgatt gctgaatgag
     4201 taacgtcata tttttcaaaa cgttccaacc aaaagtctaa tgctgcgtca cttggcacac
     4261 ggaaagaagc acgagagatc gtatctgttc ctttttttcc ttttggctga tttggaaaat
     4321 caaagaaagt catatctgtt cctggcgcac cagtatcgtc tgtaaagtaa agatggtaag
     4381 tttcgatgtc atcttggtta actgtttttt tgattaagcg cattcctaaa atatctgtaa
     4441 aaaagcggta gatttttgta gcgctagatg tcattgctgt gacgtggtga attcctctga
     4501 tttgtgtatc catgataaat ttcctcctgt taacttacaa aaagtaagta gttgatttag
     4561 acatagtata gagggtgcat ctctattttg caattaattt gtcttctaaa gtatcaggaa
     4621 ggaatcaaga atggaaaaga ggagggacgg atcaataaaa taaaaagact tacgactagc
     4681 tgtatcgatt tcaaaaaaac tagctttaaa aagctaactt tagaatcatt acgggtggtc
     4741 ataagtcttt ttatgctgag ttattttttc atttttgagc taatgcttag gatagaatag
     4801 aatgttgatt tcacgatctc ttcttgttac ttgaaactgc ttaccactgt cacgatctct
     4861 tggtaaacgg ctttttcaca acctctttgg ttaagttgaa cgcacatcca gcacagaata
     4921 gttccgaaca tcaaatcggt ttcggctgga agaatattca atcggctgtc catctttgag
     4981 atagacgact tgctgaactt ccagtacagg atcgttttct gcacagttca aatattgctg
     5041 atcatattca tcacttttat ctgcagaaat agcacgataa gcccctgcaa aatggacatt
     5101 caattcttga tgaagatgat catagataga ggctaacaaa tgttcttttt ttaaacccgg
     5161 cacaagatgg actggcataa aggtatgctc taaaacatat ggctcgccat ctaagatcct
     5221 taaccggtga atattgtaga caggttgctc ggcatcgatc atcaatcgtt cttggatata
     5281 ttgattaggg aattcaacat caaaatgaat gatttgactc ttcaaagaac gatgtctgcg
     5341 tttcatttgg agactcaaac cttcatactc gttagcgggc gatgtgtctt tttgcataaa
     5401 tggatgattc aagattttcg ttcctgatcc tcgctgcgaa tagacaagtc cttccattgc
     5461 taagatattg atggcttttt tgattgtcat ccggctcgca ccaaattctt ttaccaagtc
     5521 gacttgatta ggcaaaaaac tatcgagagg atactctttt gaacggatac gttctcttaa
     5581 aatatttgcg atttcttcgt attttggcac gttattcacc tcttctagag tataacgaaa
     5641 gattatgctt ccgacaactc gaagtagcat ctggaacatt gtttattcga aaaaagaggt
     5701 catgacaagt ttttgtcaca accccttaat gatctattaa gcaatatcta aatctggttg
     5761 tttatctagt actttcagga atgggtacca gataaaggca acgatgacaa agtcgatgac
     5821 ttgcagcata ccaccaagcc atgaatttgt tgctaagaca ccgcttgcaa tgattggcac
     5881 agtccatgga acagagacgc cagttggtgc agggacaagt ccagcagcca ttaccaaata
     5941 attgaacgtc gttacgatta gaggtgccac aacccaagga ataaggattg ttgcattcaa
     6001 tacgatcggt agaccgaaga tcgctggttc atttacattg aaaataccag gtgctaaagc
     6061 taatcgtcca acatcacgat actgtttctt tttaagaaca aaggccatca ataaaacgac
     6121 agctaaagtc attccagagc caccaatacc aacagtgaag gtttccatga atggttttgt
     6181 gatgatgtgt ggtaattctt ttccatgttg ataagcttct aagttatcaa gcatcagtgt
     6241 attccaaatc gggtccatta cagagttgac gatgatttgt ccgtgaagtc cgaagaacca
     6301 taagaattgg acaaagaaca aagcaatcaa tgttgcaggt aaactacttc ccaaaccagt
     6361 taatggtttt tggatcactt cataaacgac gtcatgtaag ttagcattga aaataccagt
     6421 catcacagca ttgattacta agaaaatagt tagtgtcact acagcaggga tcaaagcggc
     6481 aaatgatttt gttactgcag gcggaactcc atcaggcatt ttgatctgcc agccgcgttt
     6541 cgtgattctg cagtagattt ctccagccaa gaaagcagcg atcattccaa tgaacattcc
     6601 ttttgcgcca agacgatcaa gtgaaagcac accagtcaca tcttcaccgc cagcggtttt
     6661 cattgcaaaa ggcgtaagaa tcaagaagct ggcaaaagac acggcaccac cgaaaatacc
     6721 ttcaacgtca taagattttg ataaataata gccgatacca aaagtaacaa aaaccgacat
     6781 gatgctcatt gttgcatttt gcccattacc gaataaattc gataaagttc cctttgttgc
     6841 gtcactgaaa aaaggcaagt tattgataac gacaacgatc gaaccgaaca tcgttaaagg
     6901 gaaggaaagc atgaaagcat cccgcagcac tgtaaggtaa cgattttgcc ctaataaatt
     6961 agctaagggc atgattttct cagaaagctt gtccataaaa ccgttcattt ttattcacct
     7021 caaatttatt tgcaatcgat tacatacaaa gtataacgcc aaaaatttta aatgtctagt
     7081 cattttcata aaaagtattg atttattttt tagggttcgt tatgattacg gtatcaagaa
     7141 aaaagagagg aagtaaaaaa atgaaaacct acacattccc agaaaatttt tggtggggtt
     7201 ctgctgctag cggaccgcaa acagaaggaa gagtaagtga tgatggtaaa ggagaaaata
     7261 tttgggatca ttggtatgaa ttagagcctg aaaaattctt cgatcaagta ggacctgaaa
     7321 aaacttcgca agtttacaca aaatacaaag aagatgttca gttaatgaaa gaaactggcc
     7381 ataacacatt tcgtacatct atccaatgga gtcatttgat tccagaaggg acaggtgaaa
     7441 tcaatcaaaa agctgtttct ttttatcgag attattttac tgaattgctg gataatggta
     7501 ttgaaccttt tgtgaacctt taccatttcg atatgccact accactgcaa gaaaaaggcg
     7561 gatggttatc aagagaaacg gtcgacgctt atgtttctta tgcagcagcg tgctttgaac
     7621 tgtttggaga tctggtcaaa aaatggttta ctcataatga accaatcgta cctgtagaag
     7681 gaggctactt gtatcaattc cactatccaa atcatatcaa tatgaaagaa gcggtccaag
     7741 taggctatca tgagaatcta gcaagcgcaa aggtaatcaa agcctaccat gaaggcggac
     7801 atgatggtga gatcggaatc atcttgaatc tgacaccaag ctatccgaga gatgaaacga
     7861 acccagaaga tgtaaaagcg gcgaagatcg ctgacgcatt cttcaaccga tcattccttg
     7921 accctgcagt gaaaggagag tttccacaag agttgatcga aattgtcaaa gaattggcta
     7981 taatgccaga gatccatgaa ggagacctag aactcatccg tgaaaacacg attgacctgc
     8041 taggaatcaa ttactatcag cctcgtcgaa tcaaagcaaa agaaactcca atcaatcacg
     8101 aacatagccc catgccagat gattattttg ataattacga catgcccaat aaaaaaatga
     8161 atccatatcg tggatgggaa atttacgaaa aaggaatcta tgatatttta acgaatacaa
     8221 gagaaaacta tggtaatatc aaatgctata tttctgaaaa tgggatgggg gtcgaaggag
     8281 aagaacgatt tgttaacagc gaaggaatta ttgaagatga ttaccggatc gagtttgtta
     8341 cggatcattt gaaatacgtc catcaagcaa tccaagaagg aaccaattgt gtgggttacc
     8401 acatgtggac atgtatggac aactggtctt ggacaaatgc ttataagaat cgctatggct
     8461 ttatcgctgt tgatttggca caagacggta aacggacgat caaaaaatca ggtcgctggt
     8521 ttaaaacggt ctctgaaaaa aacggatttg atgcctgata ttttttgata aaacgttcac
     8581 aaaatgtttg ttctaacact gtaatcgtgc tacactaaca gtgaaggagg cgtttacaat
     8641 ggtagatact tatcgtaata ttttagtagc aattgatggt tctgaaaagg cagaaaaagc
     8701 atttcttgag gcaatcacga ttgccaaacg aaatcaggca acgttgcaca tcctgtatgt
     8761 caatgaagta acaggcaatt actttggtga ttttgcattt gttacaacaa gccttcagga
     8821 agaattggat gaggttgcgg aaaaccagat gaaagaacat cgaaacttgg caattgaaaa
     8881 aggcctgaca gatatcgaga catatgttct ttacggttat ccaaagacac tgattgctaa
     8941 tttccatgaa tcgaaagaac caatcgatct gattgtcatg ggggcgacag gtctgaatgc
     9001 ggtagaacgt gcactagtag gttccactac ttcctatgta gtcaaccacg catcatgtaa
     9061 cgtcatggtt gtaaaataaa taaattaagg gaacagaaag caaaaaagca taacgcttct
     9121 tttgctttct gttcctttta tttttttgta aaaaattact ttacctgatg aagtaatcat
     9181 gctattctaa ttacaacgac agatggagta atatggagga aagaaaatga tttcaagtga
     9241 tggaatacgc ggatacaatg atgcgattat tttatcgatc cttaacaaaa acgattctta
     9301 tggatatgaa atttctaaaa cgattcgtga gaggacaaat gattcctatg tgatcaaaga
     9361 gacaacactt tactccgttt ttgcccgttt agaaaagaat caactgattg tttcgtatcc
     9421 tggagaagtg actcatggaa aaaagcggac atattataaa atcactgaaa tagggcgtaa
     9481 tcttttagaa gaaaaaaagc aagagtggct gacgacgaaa gacgtagtcg atcaattttt
     9541 ggagggaaat taaatggata caatccgtaa ttatttagac agtcttttta tcggagtacc
     9601 tcaaagtacc gagatagata agctgaaaac tgatttgttg gcaaatatgg aagaccatta
     9661 tcatgaattg atgggagaag gaaaaaatga acaggaggcc atcggtacag taatttcgac
     9721 atttggttca atcgatgaat tattagaaga actagatgtc gaaaaaaaac atcaagctga
     9781 cgagacggaa acaaacacag cttctattta tttaagcgaa gcagaaaact actggaaaga
     9841 atacagagcg gcaagtctcc aagtggcatc aggtgttcta ttcattagct tatcttttgc
     9901 aagttttctt ttcttttgtt cagcaggata tgtgttcatg ggtatttctt gtctgatttt
     9961 cggtatagca ttagctgtcg gtttttttat tgcttctggt atgaaaatca cacgtttaaa
    10021 tcactttttg caccatcgga aaatacctga aaaagtatta gcagaagcaa aagaaaaaga
    10081 agaagagtat cagcgaagtt ttggcttctc actgattgca ggaattggat tatgtatttt
    10141 ttcacttttc ccacttttgg cttctttaat gtggtatatg gatggtagta tcggtgcctc
    10201 tatatttttt gttacggtag gaacgggtgt cttcttgatc atttatggca gtctagtccg
    10261 tcattcttat cgtcaattca ctcaaagcgc ttattactgg tgaatgtatt cagatttgta
    10321 aaaatattct atttatccgg cgtagaaaaa aagactgtga cacgcttttg tcacagtctt
    10381 ttttatatat aataatttaa aaattcatca tctaaatccg tagaattttc tagattgctt
    10441 acccatgtaa aatcgttata gacagatttc agttgacttc tgcgccattg tacagggata
    10501 aaaagacgca tgctatcttc attgaatccg actaataatt tctttccgtc agtaatgatg
    10561 ggacgttgta acaaagtaaa atgcgagacg atcagatcga caagctctga ggtcgtacat
    10621 tggtcgattt ggtctttcaa atttttataa tcaatcgagc gtttagctaa tagatcgtca
    10681 aatccgtttt ctgttaatga caataaataa aatatctctt tccttgttaa aggctgttta
    10741 ggtgtgaaaa ttcgttctct gtaaggcatt tgatggtctt tcagccagtt tgccatcaga
    10801 tggtaactat gtgtgcgaga agaatagatc gtaagcataa aaaaactcct taaatagtcc
    10861 attaatttgt tagatctgtt gagataaata ataggtaagg agctgtgcat aagcattgat
    10921 caaaacaacc caaacatcat tagaaataac tttctaaagt cttaaacttg cgacgagaaa
    10981 caactagact aatagaaaaa atgtcttagc catttggctt cctgtttgtt tttttgctta
    11041 tgctgcagct cctcgggaaa gggttctaac aatttgaaga aggttgatga ttgatctagt
    11101 ttaaattgtg tgaaatttga aatctggtgt ttttactaga tgaatcacct aacaactatg
    11161 attataactt atagaacttc tgttttgcat tcggttttgt tatagttgtt ataaagtttt
    11221 attttattac agaacatttt taattaataa agaacagtta gaagttaaaa ttgctgattc
    11281 acatagagtt tatgacttct tggaaattct ttttcaatca gttttttcat ctgtttatga
    11341 aattcttttt tttcagtaaa cataaaggtt tgggtatcgt aaccttcttc atgtaggaaa
    11401 tagattattc ctttttctgt gttttgcgta taagctttta tactcctgtc ttttttgaaa
    11461 gaacagatcg tatagccatc tatttggtct ggtagtcgtt tgattttctt caaaatgact
    11521 tttttatcct caagtttcat ttttttcacc tgactttatt tttttcatat ggaaatcata
    11581 gcgcctttgg ttatatgaaa acaagaagga tactgaaata tatataaatc aaatagtggt
    11641 tatttattat tagaatagcg aatacaaata aacgaccact attttctgat ttattgcaaa
    11701 tgttttttca aataaatttg attaccaaga aaaggtagtg gtatatttac tgagggatac
    11761 tttgaaaaac atatgataga aacagtaaca gtattatgaa aaatcttttt ataaaaatgg
    11821 aggaatcgat ttgatggaag atcagtatgt acaagcaatg acgatcgcag gatcagatag
    11881 cgatggaagc gcagggatgc aagcagatat gcatacattc tttacaagaa atgtttacgg
    11941 tgtttctgtc atgaccgcat gtgttgcagg taattcttac ggaatcggag caagtgtgac
    12001 attgccaaca gattttatcg acaaagaatt tgaactgatt gcgaaggact ttcaaatacg
    12061 tgcagctaaa acaggtatgc tagcagattc aaagttgatt gagacagttg taaaaaatta
    12121 ccaaaaatat gattttggac cattagtcgt ggatcccgta atcgtaacga aacatggaaa
    12181 tcttttacta gaagaatctg ctttgcaaag cttgaaagaa aagcttgtcc ctttggccga
    12241 agtactgaca cctaattttt atgaagcaga aaagctgact ggacggacat tagcagctga
    12301 agaagatttt gtgcaagcag caaaagaact gcaagatatg ggtgcaaaaa acgttatgat
    12361 caaaggacat catgctaaaa atgcgcagca agaaacagtc aatgactacg tattgttcga
    12421 atcaggaaaa tcattttggt taaatgcacc attttatcct accgaccgga tcaacggaac
    12481 tggcgattcg ctatctgcat gtattgcagc tgagttagcg aaaggaaaaa cagttgaaca
    12541 agcgatccga ttggcaaaag actatgtaaa ccgtgcaatt cgtgaagaaa taaatgtagg
    12601 gcacaaatat ggccccatca atcattgggc agctggtgaa ttagagtaaa agaaagaagt
    12661 tgtgaaaaag ttgccctgca tcaagtaata agaacagcca agtaaaaaca gcttcttatg
    12721 tttttaactt ggttggactt attaccgcag atgcaagctt ttgaacaccg tttaagaaag
    12781 aggtcgtgag cctgccgtcc agctccgagt cacaaggaac aagttcaaaa aacagcttct
    12841 catgtttgtt gaatattgtg acttgtgacc gaggagttgg caggagaaca ccgtttgttc
    12901 ggaagaaggg actgtgacaa gatttttgtc acagtccctt taatcttagt atatttttct
    12961 ctacttgaat aaaaaaatta taggattgga gaaaataatc gagaaatttg ttgcttgaat
    13021 aatagccagt tagacatttc cttgactgtt tcagttgtca tggatgaaca atgtgtctca
    13081 tcttctttga actgagtagc aagttcttct aaaaactcag gatcgtaaat gacagcactt
    13141 gtttcaaaat tcaatcggta gctacgaata tcttgatttg ctgaacctac catgcagatt
    13201 tcatcatcca ttatcaatgt ttttgcatgg aggaagccgt tctcatagac aaggatttgt
    13261 acattttcct tgatcagctg ccgagcataa tattgtgttg ctcgataaat aaaaggatga
    13321 tccggtttgt tgggaatcat gattttcaca tctacaccag aggcagttgc gatttttaaa
    13381 gcagcaatga cactttcatc aggaacaagg taaggtgtct gtatccaaac acgtttttta
    13441 gcagaagtaa tcaatttgat aaatgaaagc ttgatttgtt ccctttcgtt attcggtccg
    13501 cttgaaacaa gctggatgga tgtatcagca agcttagatt catctcgatc tgctttttta
    13561 aagaaataat tcaaatgata gccgaccttt ttttcttcag gtaccgagac gttccagtct
    13621 gttaagaagc gaagctggag caaagaagaa gcggcaccga aaatccgtat atgcgtatcg
    13681 cgccaatagc cgaatttttt tgttgtattt acatattgat tggcaatatt gaaaccaccg
    13741 gtataactaa tctttccatc gatcacaacg atttttcggt gatcatggta attcaatcgg
    13801 aaacgaagta atgccctttg tgaggtaaca aatgtatgga catgtccacc atttttgatt
    13861 agacgattga aatcttttgc ttttgtgcca tgagagccaa atgcatcata taatattcga
    13921 acttccacgc cttctgcggc tttttcttct aaaacatgta agacttgctg gccgatatta
    13981 tctgtcacaa atgcgtaata ttcgatatgg atcgaatgtt tggctttttt tagatcttga
    14041 agcagtgaat ccaatttctc ttgtccgtct gtgagaagag tgacagaatt cattcttgtc
    14101 agcggcatac gatttaatga agagaagaag tcaacaaatt gctgtttgtc tttatcgccc
    14161 atgtcaggat cgtaatgttc aatggtatct cctctaaaag actgaaagtt ttctaattct
    14221 ttcaagtcac tttgtcggag atagaatttt ttcttatccg ttaatccacg tccgaaaaat
    14281 aaatataata caaagcccac cccaggaagg gcaaacaata ctaagagcca tgcccaaatg
    14341 gctgctacat ctcggggttt gatcaaaata gccaccaaag caataagtgc atttaataga
    14401 taaagggcgg ttataatact agataccaca aaaatgttcc tccttacata caataacatt
    14461 agtatagcat gatagaagaa agaagcctac caaggtgaat atacttttca ctcctttcat
    14521 gaaaatgtag gtaaatcggg ctaaagtagt tgctttttgt aggttaataa ggtaggatat
    14581 tagtacagtt gaatatctcc ttaggggagt aaccggcaac gtttgttgcg ataatatcaa
    14641 cagtaagtta accaaatggt tttctggtat tgtatgaaat ggtgagacct aagacaaatg
    14701 cgtatttgtc ttaggtctct tttttttcag acaggactag ggccaagatc aaaaaatggg
    14761 ggatgaaatt tggaaaacaa ggaacaagca caacaagcgg tctataaaga aacgatcgac
    14821 tcgttgatgc agcaaacgca gagctcaacc gatggattga gcaccacgca agcgaaggaa
    14881 aaattagaaa gagatggctt gaaccagcta aaagaaaagc cgaagaagcc aacttggaaa
    14941 ttgttcttag aaactttcaa agatgcaatg gttatcgtat tgctgattgt cgcactgatt
    15001 cagatggtca tgggtgacta catcgaattc ttagttattt ttgcagtatt gatgttgaat
    15061 tctataatca gtgttgtcca aacaaaaaaa gcagaaggtt ctttagaagc gttgaaaaac
    15121 ctttcagcgc ccgatgctcg agtgattcgt gatggtaagg aaaaaacgat tccggcaaac
    15181 gaacttgtgg taggagatat cgtgttgtta gacgcaggcg attatgtacc tgctgatgga
    15241 cgtttactag atgcgggatc attaaaagta gatgaaggta tgctgacagg agagtcgact
    15301 tctgcagaaa aagaagtaac ggatatcaca agtacggtac caatcggaga tcgtacaaat
    15361 atggtattca gtggaacgat cgtaacttac ggacgcggta aattcttagt gacttcaact
    15421 gggaataata cggagatcgg acaagttgct ggccttttgg aatcaacaac tgagcaagtc
    15481 actccgttac aacgaggtct ggataaattc agtaaaaaac taagtttggc tattttggca
    15541 ttgtctttat tgattttagg tatccaactg tttcgtattt atcttggaga aggtacagga
    15601 gatatgactg cagatatcgt cagcgcagtg atgtttgccg tagccgtagc cgtagctgct
    15661 attccagaag cattacagtc tatcgtaaca atcgtgttat ctttgggaac gaataaaatg
    15721 gcaaaacgtc atgccattat tcggaagctt ccagcagttg aaacacttgg ttcgacaagt
    15781 atcatctgta cagataagac tggtacattg acacaaaaca aaatgacagt tgttgactac
    15841 tttttaggta atggcgatac tggggatttc acaaatgacc cttcaaaatg gacagctgac
    15901 gaacgtcgct tgatcgaaat cagtgtttta gcgaatgatg catcgatcag tgaagacggt
    15961 actaaattgg gcgaccctac ggaagtagcg tttatcgact ttagtgaaaa attaaaccag
    16021 ccttatcagg aaatccgaaa caactaccca agacaagcag aacttccttt tgactcagat
    16081 cgaaaattaa tgtctactgg acacacaatt gataacaaaa attacttgtt tgttaaaggc
    16141 ggaccagata tcgtcttcca acgcagtaaa aaagtattgc taaatggtga agtcgttccg
    16201 atgacggatg aattgatgaa aaaattccaa gagcaaaatg aagctttttc aacacgcgca
    16261 ttacgtgtac tagcttttgc ttaccgtcca cttgataatt ttgatttatc atttgaagat
    16321 gaagacgatt tgatccttgt tggtttgctt gctatgatcg atcctccacg tgctgaagtg
    16381 actcaggcgg taacagaagc aagaagtgca ggaatcaaaa caatcatgat tactggtgac
    16441 cacaaaacaa cagctgttgc tatcgcaaaa caaatcggga tttttgaaga aggaaacctg
    16501 gctttgaccg ggacggaact agatgaattg acagaagatc aactaaacga agttttagaa
    16561 aaagtcactg tttatgcacg tgtttcacct gagaataaaa ttcgtatcgt tcgtgcttgg
    16621 caaaataaag gtcatatctc agctatgaca ggtgatggtg taaatgacgc accagcattg
    16681 aaacaagcag acatcggaat tgctatggga acgggtacag atgtggcaaa agatgcagca
    16741 gcgatggtat tgacggatga taactttgct tctattgtca gcgcagtaga agtaggacgt
    16801 aatgtgtttg ataatatcaa gaaagctatt tcttatctat ttgcaggaaa tttaggtgcg
    16861 atcattgcga tcatctttgc cttagttgct gactggtcca atccatttac agcattacaa
    16921 ctgttgttca tcaatttagt caatgattca ctgccagcaa ttgcattagg tacagaaaaa
    16981 gctgaacctg ctacgatgaa ccgcccgcca agagatccaa attcaggaat ctttacggac
    17041 aaaacattga tttctgtaac gtatcgtggt gtgctgattg ggattgctgt tatctttgct
    17101 caatggcttg gcatgcagca ttcacctgaa ttcggtgtag ccatgtcatt ttcaacattg
    17161 atttggtgtc ggacattgca aacattccca gcacgttcaa acacacaaac agctatccaa
    17221 gcagggttct tctctaacag aagtgtctta ctagctgtag ttgtatgtag cgcgctttac
    17281 tgcttaacaa tgatcccagg actgaaagaa gtcttctcta tcccatcagc atttggattg
    17341 acagaagtct ttacatgtat gggaatcgca cttgtgacaa ttgttttgat ggaaatcact
    17401 aaattgatca ttgtacgagt acaaggaaat aaataaaacg aatcaacgag gttgtgagcc
    17461 tgccgtttaa ttctgagtca caaggtgcaa tttcaacaaa cagcttctca tgtttgttga
    17521 atattgtgac ttgtgaccga agagttggca ggagaacacc gtttaaggaa gaagttgtaa
    17581 aatcagcatt ttgagctaat actgagggtc atctgattgg acactgttta ttcggaaaga
    17641 gggactttga cacgactttg gtcacagtcc ctttttttat ttatgataga cggaaagcca
    17701 atcattttat tattcatcaa aagagataga atagataaaa gaggagaatg atttattccg
    17761 aaaagtgaaa acatataaca aaaaattaga ggaaatcaaa tgaatgaaaa agaatgggat
    17821 gaatttgctg aagaatatta tgaaatccag caagaatcgc aagtaactat tgctgaagat
    17881 gtaaaaaatt atctgaaaac ggagaaagtc ctgcctgctg aaacagcagc agacgttgct
    17941 ggaggatctg gcagatttct ttccttagca aaagaaatta atcgctatga tttgatcgat
    18001 ttttcttcag gaatgctaga aaatgcaaaa aaagaagcag aaaaaaatga gttgccaaat
    18061 gtttccttta tcaaacagtc gttagaagaa tttatccaat caaatgagac atatgaaatg
    18121 gtttttacag cagcaaatcc agcattggta catcttattc aattagaaaa attgatgaaa
    18181 aagtcaagca aatggtgcgt gataatcaga gtagtggaat caatcgatga tgttttttat
    18241 cctatcgaaa agcaactagg aatgatagaa gaagatccta atacatcgcc agttgtaatg
    18301 gatcaatttg aaacatactt aattgatgaa ggattcaaag tgaagaaaaa agattttact
    18361 tattttacac aggaatcaat tactgaagaa ttgatgaagc tatactatga cgcgtacgca
    18421 aaagatcctg ttgtgaccag gtacattcgc aaactattca gtgaaaaacg agaaatcctt
    18481 agtacgacta agctgaccta tagactgctc ctttggtccg cagataaaaa aagaaccttt
    18541 cacgactcgt gaagggttct ttttatgatt ttattatatt ttgtagtaac gaatatcatt
    18601 ttcgatcttt gtaatcgaaa aaggtacatc tgaagtatat tctgcacatt ctccgtgttc
    18661 aggaagcgtc tcactgaaaa tcgtttcata ttcgtcaaca gtgatccgtg ttcgagaatc
    18721 tagcatctct tgatgagatt gtgcgaagag atattcttga tagttttctt ccagataacc
    18781 tgtaaaaaat tcacttactg caccagaacc gtagctgaat agaccgatgc gatctcctgg
    18841 ctgtagtgat ttcgaatttt ccagtagaga agttagcccc aggtataatg aaccagtgta
    18901 aagattaccg attcgtcggc tgtaacggat gctttcttca tagcgagcca taagacgttc
    18961 ctgattttct tcgtctgttt ggtctaatac gctttgcaat gccttttttc ccatcttagt
    19021 atacggaata tggaaagcaa tcgcctgata atcttcgagt cctcgacccg acaattcttt
    19081 atgtcgattc caaacttttt ggaatgattc gatatacgta gaattagata aaggaccatc
    19141 aacaacagga aattcgctat aatctggacg ccagaaatca tagatatctt ctgtcagaaa
    19201 tacgctgtcg tcttcaatcg ataaaatacg cgggttttga gtgatcatca tcgcaacagc
    19261 accgacacct tgcgtcactt caccaccgct tgccaagccg taacgagcaa tatcacttgc
    19321 tatgactagt acttttcgtt ctggatgatt tttgacatat tctttcgcca tgtgcaaagc
    19381 tgcggtgcca ccgtagcaag cctcttttac ttcaaaagaa cgagcaaaag attggatttt
    19441 cagtaaatgg tggataatta ccgcactcgc ttttgaatga tcaatcccgg attctgttcc
    19501 gacgatgacc atgtcgatta gctcacggtc tttttctgtt acgattttgc tggcagcatt
    19561 tgctcctagt gtaatgatgt cttcatttgc acgattgact gccatttggt cttgaccaat
    19621 ccctatatgg tattttgcag gatcatcccc acggctttct gccaactctg tcatatctaa
    19681 atataaatta ggaataaaaa aggaaagacg atcaatccct attttcattt caacacctct
    19741 ttacttatga taaaaaactt actttactaa ggtatcataa aaagattaaa agaaatataa
    19801 aaaagagaat atttaaggat tgttaaaatt taatcttaga aaaaaataac tggaacaaga
    19861 gctatttgtt tttacagcaa agaatggtat atttttgtag gaggtggctt acttgaaaga
    19921 agtcgttatg atagatgctg caagaacgcc gataggaaag tatcgcggaa gtttaagtcc
    19981 atttactgca gttgaattag gcacacttgt gactaaagga ttattagata aaacaaaact
    20041 gaaaaaagat aaaatcgatc aagtaatatt tggaaatgtc ctgcaagctg gtaatggtca
    20101 aaatgttgcc agacagattg ctttgaacag cggtctccct gtagatgtcc cagcaatgac
    20161 gatcaatgaa gtttgcggat ctggtatgaa agcagtgatc ttagcacgcc agctgatcca
    20221 attaggtgaa gcagaacttg tgatagccgg cggaacagag agtatgtctc aagcacctat
    20281 gctgaaacag tatcagtcag aaacaaatga atatggtgaa ccaatttcca gtatggtcaa
    20341 cgacggattg actgacgcat tttcaaatgc acatatggga ttaaccgcag agaatgttgc
    20401 aacacaattt tctgtgagca gagaagagca ggatcgctat gccttgtcgt cccagttgaa
    20461 agcagcacat gctgtcgaag ccggtgtatt ttctgaggag atcatcccag tcaagatttc
    20521 tgatgaagac gtgttatctg aggatgaagc agttcgtgga aatagtacat tggaaaaact
    20581 gggcacgtta cgtacagtat tctcagaaga aggaactgta acagcaggaa atgcttcccc
    20641 gttgaatgac ggtgcctctg tggtgatcct tgcatccaaa gaatacgcag aaaataataa
    20701 tctgccttat ttagcaacca tcaaagaagt agcggaggtc ggtattgacc caagtatcat
    20761 gggaatcgct ccaatcaaag ccattcaaaa attgacagat agatcaggaa tgaatttatc
    20821 aacaatcgat ctttttgaga tcaatgaagc atttgcagct tcttctatcg tagttagcca
    20881 agaactgcag ttagatgaag aaaaggtcaa tatatatgga ggagcaatcg cattaggcca
    20941 tccaattggt gcaagcggtg cacgtatctt gactacatta gcttacggat tgcttcgtga
    21001 acagaagaga tacggtattg cttcattatg tattggtgga ggtttaggct tggcagtctt
    21061 gttagaagcg aatatggagc aaacacataa ggatgtgcaa aaaaaaaagt tttatcagct
    21121 tacgccatct gaacggcgca gtcaattaat agaaaaaaat gtattgacac aagaaactgc
    21181 gttgattttt caggaacaaa cactttctga agagctctcc gatcacatga tcgaaaacca
    21241 agtgagtgaa gtggaaatcc caatggggat cgcgcagaat tttcaaatca atggcaagaa
    21301 aaaatggatt ccgatggcaa cagaggaacc atctgtcatt gcagctgcaa gtaatggtgc
    21361 aaaaatctgt ggaaatatct gcgcagaaac acctcagcgg ctgatgcgag ggcaaatcgt
    21421 tctatcagga aaatcggagt atcaagcagt gatcaatgca gttaatcatc gaaaagaaga
    21481 gctgattctt tgtgcaaatg aaagttatcc ttcaatcgtg aaacgcgggg gcggtgttca
    21541 agatatctct actcgggaat tcatggggag tttccatgca tacttatcta ttgatttttt
    21601 agtggatgta aaagatgcaa tgggcgctaa catgatcaac tcgattcttg agagtgtggc
    21661 aaacaagtta cgggagtggt tccctgaaga agagattcta ttcagtattt taagtaattt
    21721 tgctacagaa tcattggctt ctgcctgttg tgaaatccca ttcgaacgct tagggagaaa
    21781 caaagaaatc ggtgaacaaa ttgccaaaaa aatccaacag gcaggggaat atgcgaagct
    21841 tgacccttac cgtgcagcaa cgcacaacaa agggatcatg aatggtatag aagctgtagt
    21901 ggcagctaca ggaaatgata cacgtgcggt tagcgcttcg atccacgcct acgcggcaag
    21961 aaatggatta taccaaggat taacagactg gcagatcaaa ggggataaac tagttggaaa
    22021 actaacggtg cctttggctg ttgccacagt aggcggagct tccaatatcc tgccaaaagc
    22081 aaaagcatct ttagctatgt tagatattga ttcagccaag gaactagcac aagtaattgc
    22141 tgcagtaggg ttagctcaaa acctggctgc tttgcgtgca ttagttacag aaggaatcca
    22201 aaaaggccac atgggacttc aagctcgttc attagcgatc tcaattgggg ctattggtga
    22261 ggaaatcgag caagttgcga aaaaattacg tgaagcagaa aagatgaacc agcagacagc
    22321 tatacaaata ttggaaaaaa tccgggaaaa ataaaaaagc aatatcttta gaagaataaa
    22381 gcaagattta cagttatttt atttactgca gatcttgctt ttttctctat cagaaaatat
    22441 gtttattatt agaatttttt atagttaagg ttaggcatct taagaaatca ggcaactcca
    22501 agatatcttc aggtagaaga gaagtcgcct aacattgtag gatcataggt gatttgttgg
    22561 acaggtcaag ctgatatttg agcctgatgt tagaaggaat ttctttttac ttgctgtaga
    22621 aattattata tgactaaaaa ggctgggatt ttaaatccca gccttttatg acaaatagaa
    22681 tttttatcga tcagtaatcg ctgtcgctgc aaattgttcg atcaaaggaa tcaaagtcaa
    22741 tttgactttg tatttccgtt cgagtgcttt ttcgataacg aactcatttt cagtagtcat
    22801 agaaatagtt gctaatttac gaggttcatc agcatttttt tcattaataa ctacttcatg
    22861 ttcattttgt tctgtgtaaa atttaggata ctcagcaacg gcttttgaaa aatcagcaaa
    22921 acttaaagcg gcattcgtat cagttgagcg tgtattttca gttgtgtccg cttttggttt
    22981 ttccgttttt tcttctggca cactgactgt ttcttctgta actggtgtcg caacagcttg
    23041 cgcagttggt tcatcgtttt tcaatcgttg atcattccag taagacacga tttcaataag
    23101 aagattgtca cggaatcgtt cgaaaatccc gttttctcct gaacgaattc tctttaatac
    23161 agtattgaag ttgtcatcga ttggcacgtt gatccgtgta tcttcatttg ttttcccagc
    23221 taatccgatc gttaagattt gacggttttt gggatcaagc atgacttgta acggcaaacc
    23281 ataacgtcgc aagctctctt cttctagaga acggaataat tgtcctctta caccatccaa
    23341 tgaaggacgg aattgattta ataatttttg tttctgtttt ttcttcatat gttctctcct
    23401 tcgctcatac cctttcgatt ataagaaaaa aacagccaaa tgaaaaggag taatgcaaaa
    23461 aaacttgcgt atacgcaaat tacaacagaa aaatttgcgt attttcccgt tttttgaaag
    23521 aaaaataaaa aatggaacgg attatgtata tatacataat ccgttccatt ctttctattt
    23581 tttcggtatc aaggcaaaaa caggtagttc aggtgaataa atgacttcat gttcgtgcca
    23641 gggtttgacc attagcgaat gatcgaaccg ttttttcagt tcttcgatga tttgatcatg
    23701 tgtccagttt cttgcaggaa aatgttggat tttctctgca tcgatcaaaa agacaaaatc
    23761 ggaatgaaaa gtctgggtaa cttcttccga gagagaattc aagcgttcga ttggatccat
    23821 aaaatcacct ttcgacttaa aattgggtag tatctgggtc ttttgctttg ccgactacac
    23881 catctaactg atcgatttgt ttcatttctt cttctgttaa ttcaaaatca aataattcag
    23941 tattttcttt gattctgctt ggtgtcactg acttaggaag aggaaggaat tcgtgttgca
    24001 gcgaccaacg caaagcaact tgtgcaatcg tcttgtcatg tgcttcagcg atttgtttca
    24061 tttcaggcac atcgaagatt ttaccagtgc ctaatggact atatgcttcg aggatcatat
    24121 catgtttttt tgcatactca actacagttg tctgtaattc gcctggtgca aggaaaactt
    24181 gattgaccat cggcataatt tttgctgttt ttgctagtgt atctagatgg tggggtaaga
    24241 aattgctcac accgattgct ttgattttac ctgcttcata cagttcttca aatgctcgcc
    24301 atgtatctgc atttgcttgt tcccaattat cacgaaaagc aacagggttt ggccagtgga
    24361 tcaaaaacag atctaaataa tctgtttgga gcttcttcaa tgattcttca aaagaagaca
    24421 tcacaagttc atagctgtgg tttgcattcc ataattttgt tgtcaagaat atctcttctc
    24481 taggaattcc actttcctta atcgcttggc cgacgctttc ttcattcttg tatccttggg
    24541 cagtatcgat atggcgataa cctgcagcca gcgcttcttt aacagaggaa acagcgacat
    24601 ccccatcagg tgtttgccat gtgccgaatc ctactaccgg gatttcgtaa ccatttgata
    24661 gacgataagt gcttgttaat gaattcatac tttcagctcc ttttttattc gttcaactat
    24721 aagtgtagcg catttttcga aaaaaagaat ccattttgtt tctactcttg aaatttttgt
    24781 ttaaaagaaa atgattttga ttctggtatt tttgattttt tttccgtaaa ctaagacaga
    24841 agggaatgag aaaatggata tctatttaaa aaaagcaatt ctgcatatta ttgacagaga
    24901 aactggttct ccagtctttt cacaaaaaga gctggatctg acaaaagaat atattcgtga
    24961 ttttcttcaa aagaagatcc aaaaaatctc ttctgctcaa acaaaaactg gacaactagc
    25021 agaagaaagc atgatcgttg aatcacttaa aatcgctcaa gaaaattttg tggaagcaag
    25081 tgaagcaatc gttcagcggt ggttcgatat ctaccaagaa agtgaagaag cacctagtgc
    25141 agatgtattt gttgtcttgt atgaattaga tacagtgatg tacttatctt tattgaaagt
    25201 caattatcgt gaggcttaca ctcactttgt tgaagcagac gaagcaggga tcgacaaccg
    25261 cttgattttg aatcgagcaa ttctaggggc gaaaacacaa aaagcagatg aagcattcgc
    25321 tgtgaatttg actgattgga cctacgaatt aattgaaaaa aaatatgagt tttctggcaa
    25381 aaaagagctt tatttttctg gaagagtgat cgaaagtgtt cctgcacctt ctttagaaga
    25441 aaatgtaaaa gtgatccaaa aagtagccaa gcatcttgga aaaaaatttg agacagaaga
    25501 atttgatatc atggctgatt tgaaagaagc tgtctatgat acgatagaag aaaaaggtcg
    25561 gttggatcat gagatgattg cggaaaaagt cttcaaggaa aacatcacgg caaaaatggc
    25621 ttttaaagaa gaagtacaag agcaaggatt tgtcccagaa gcacctcctg taaaagaagt
    25681 acaagaaatt tctgagaaaa aatttggaaa acaaaaattc aagctatcaa acgggatcga
    25741 actgatcgta ccagtagatg tatatcgcaa cccagatttg attgaatttg tgaataatcc
    25801 ggatggtacg atatccgtga tgatcaaaaa tgtggatgaa gtattgaatc gtttataaaa
    25861 atgactagaa tattaggtgt tcaagtacca gtgatcagtt aaatgaattg tgtcaagaga
    25921 aggatcggaa aagacgaata taacaaaaaa agagcgtgag acaaaagtaa agaacacttt
    25981 tgtctcacgc tctaaacacg tataaacggc ggaagcagaa gcaactcctt cttatttctt
    26041 ggagttaaac gcttctgtcc cagcctcttt ttatctaata aaattttaag accatttact
    26101 aattatcgat tttttctgcc gcatttttag gcacttcaga agcctttatt tcttcccagc
    26161 ttaatacacc tttacgagga ttgactttga gtttaagata cgcattcatc tttaatggat
    26221 gttctctttc ttcgcgaagc gtcacctgtt ttttttcacc atctttatta taagccgctt
    26281 gcttgtaggt ataagtcgtg aatttctctc cgttatctgc ttgggtagct gacatttcgc
    26341 cattcgtcgt gatttttgta taataagctt cgccgccgta aaaataatga taagctgcaa
    26401 aacttccgcc gagaaatatg cctaaaacga caagtacgcc aattaatttt ttcatgtact
    26461 tcacctcttt ccttattatt aacgaaatag aagatttcgt ctattgaaag ttgttggcaa
    26521 cagctgaatt ttaaactttt cctcattttg ttcttattgc ttcaaaagaa agttaaggac
    26581 tatcttgaag tttttctcaa aaaacacatt tttttattta taaaaggtac ttttttcgcg
    26641 tataagacag acgagtgctc ttagttgact ttgaccaata ttgacgtata ataagcttag
    26701 ttcgaatctt acaaaaagta agtcggacgt attctttttg atttagtcaa aaaaagacta
    26761 taataaaaag gtgagagctg aaatttttca gtgatctata ttatttagga ggtttgtaaa
    26821 ttatggcaaa agaacattat gacagaagta aaccacacgt taacattggt acgattggac
    26881 acgttgacca tgggaaaact actttaactg ctgcgatcac tacagtatta ggcaaaaaag
    26941 gcctagcaaa tcctcaagac tatgctagta ttgatgcagc tccagaagaa cgtgaacgtg
    27001 ggattacgat caataccgca cacgtagaat atgaaacaga aaaacgccac tacgcgcata
    27061 ttgatgcacc aggacacgcg gactatgtga aaaacatgat tacaggggca gcacaaatgg
    27121 atggtgcaat cttagttgtt tctgcaactg acggtccgat gcctcaaaca cgtgaacaca
    27181 ttttattgtc acgccaagtt ggtgtaaaat acctgattgt tttcttgaac aaagttgatt
    27241 tagtcgatga tgaagaattg atcgatttgg tagaaatgga agttcgcgag ttattgagcg
    27301 aatatggttt cccaggcgat gacactcctg tgatcaaagg ttccgcatta aaagcattgc
    27361 aaggcgatcc agatgctgaa gctgctatta tggaattgat ggatacagta gatgaatata
    27421 tcccaacacc agaacgtgat acagataaac cattactatt gccagtggaa gacgtcttct
    27481 caattacagg tcgaggaact gttgcctcag gtcgtattga tcgtggtgct gttcgtgtcg
    27541 gtgatgaggt agagatcgta gggatcaaac ctgaaacaca aaaagcagtt gtaacaggtg
    27601 tagaaatgtt ccgtaaaacg ttagattacg gggaagctgg ggataacgta ggcgtgttgt
    27661 tacgggggat ccaacgtgac gatatcgaac gtggacaagt acttgctaaa ccaggttcca
    27721 ttactccaca tacaaaattc aaagcagaag tgtacgtgtt gacaaaagaa gaaggtggac
    27781 gtcatactcc attcttcaac aactatcgtc cacagttcta cttccgcaca actgatgtta
    27841 caggaacaat cacattgcca gaagatacag aaatggtcat gcctggtgac aacgtgacga
    27901 ttgatgttga cttgatccat ccaatcgctg ttgaaaacgg aacgacattc tcaattcgtg
    27961 aaggcggacg gacagtaggt tcaggtatcg ttacagagat cgaagcataa gaaacgcgac
    28021 tcgaatattt tggtaatgaa aaatgtttaa aataaaagag cggtccaaac aggatttctg
    28081 tttggaccgc tctttgttct tcaattgtat aagaagagat tgtagaagca tgaactttcg
    28141 ttttacttca gtctctttta ttcatcatga gagtgttcat ctatcggtat gcagttttta
    28201 atactttctt cgtatccatt ttttcaaacc acttattcta ccttgtgtct gctcaactgg
    28261 cgcattatca ataatcagca aagcaatcat aacatatgca atccaactat ctctagaata
    28321 tagagtataa cgtgagaccc agtttgtagc gtacttgctt ttatattctc ttaatccatg
    28381 gaaagaataa aaatgagaac caaactcgta aaccaagtat gcaatccttt cctgtaaaaa
    28441 actctttctg gaagttccga catttgaaag aggggccatc cctaaattga accattggat
    28501 atgttcttct ttcatatagg caaacaaatg caagaacaag aaatccatac tgccagaagg
    28561 tgctttttta gaatcatatc gcatcagatc aatcgttcct actttattgt tcgtgtaagt
    28621 aggcatgatc gttgcaaaag cgacaatttc ttcttgggta tttttgacaa ctgcaatagg
    28681 cgctctttgt agataatctt cagagaaaaa gcctaaagaa aacccttttt cctttcgtga
    28741 acccaaccaa ttatcagaga tatttttgaa agtactcatt tgctcagtag aaaatggtgg
    28801 ttgtaagaca tcaaatgtaa atccttctcg ttcgatccga ttcaagacag cacgagtgcc
    28861 cttcattttt ttccctgaag ttgtaaaact attcaggtct acataagctt cttcccccat
    28921 cttaatgaaa tcgtagccga attcatgcaa aatcataaca atctcttcgc ttgtttcgta
    28981 gaaaactggt aaatagcata gtcgatctgt ttcttcgata aaagcttcga ttgcttctgg
    29041 aaaatcttct ttcttaccag aaggatcacc cattacaata catttattat tgaagcaagc
    29101 gaattggaga agaacagttg gttcaccgtc tttttcatag gcaaacatcc gcttatcttt
    29161 taagaagatc aattgactat cggagtttcc tccataagtt gtaaggatct tcagggcctt
    29221 ttcttcatta aaggcttcgc caatctgttt cttttctcct tgaaggaaat gaacaaatag
    29281 aacgatcatg aaactaacag cgatgatggc caacaatccc gaaaaccaaa tcttttcaga
    29341 aggaaataag aaaaaggaaa taaaatggtg acgccgatga gggaaatccg gcagattgta
    29401 taccccaata acgatgtaaa gcaaggacag tgcaccaata atgattccat cgatcgtacg
    29461 ccactcccat gaatagatca attgttcccg aaataattcg tttttagaag caagaatgat
    29521 cagaagcaga atagacaaga aaaccaccgg tgtgaaacta aaatcactta ataaaacata
    29581 aagtaaagct agaacaatca agaagattgt aggcaaatat gctcgtttca cacgtgctgc
    29641 gatccctctg cccataatga ttaaaagaaa tcccaatagt atactaggaa attggataat
    29701 aaaatgaaat ttcaatgggt tcaaactatg aagccagcga aactctgtaa aagcttgcgg
    29761 gatagtggca gaaagtacta gcatgattcc agaaaagtat aataagacaa ccacgatttt
    29821 atgcgcaatt tctgttgcta attgtttagg gataccagaa taacgctgat caaaagtgga
    29881 accgatattt ttgaagaaaa agacgattcc aatcaaaaac ggaatgatgt agtagaacag
    29941 gcgatagagc aagatccaca caacgactat ttctcttggc acaccaatag cggacaaccc
    30001 gataatcatc attacatcga aactcccaat ttctcctgga atcatagaca cgattcctat
    30061 cactgaagca gcaatgaata atggaattgt ttgccacaga tcaatccgga tttccattaa
    30121 ataaccaaca gaaaggaaac taaacaggac accggtccat tccaacaatg aaactagcaa
    30181 tagctgtcct tgagttttaa gtgaggtacc accaaggaat cctttctttt tgaaagtagt
    30241 aaataaaaag acgacaggaa aatatagacc gccgccgatc aaccatatcc aatattgctt
    30301 caaaaaagga gcaactggcg tgaagactac aagtaaaaaa gaaagcagac tgtaaataga
    30361 aagtccagcc atcaaaaaca agaaaacttt cgataatgct tggatcacgt ttctgctctc
    30421 tttcttttgt ccatatagtt cagagcgaag ccccacacta acaaacccgc cgaaaccggc
    30481 aatattgttg atcgtattga tcagccagct tgtctcaaac aggtaacgag gattctgctt
    30541 ttgttcaagc atccgattca aaataatatc ataaccaacc ataggtaaca cagagataag
    30601 accaatcaat agcattagtc cgcttttcca tacaggtata gtggcaaacg tttctcctaa
    30661 ttgctggata gatagagttt taccgatgga catcaattca ccgacaataa tgacaatgac
    30721 agaaatcaaa aagattgttt tgaacagtcc taggtggttt ttcagccatt gtatggtatt
    30781 ttttaacaaa taaatcacct tctattccta atagttatgt ttcagaaaga aattgaagaa
    30841 cttctcgatt gaagcgttca ggatcttttc tagctaattc atgtccttgt tctttcacaa
    30901 gcacaaagga agcttttggt atagttttag ctatatacaa agaatgtttt agcttgatta
    30961 catctttttt tcccacgatg atcaaagtgg gggagttgat tttttttaaa tcattttctg
    31021 taagcccgat gtcatgcagc aaaagtttga taactaaaag atttttgcga agacttgggc
    31081 gaaataaaga gagtaaccat acccatgcat aatgaatatt actgatgact ctggcagaaa
    31141 aacgaacgcc tttaacaagc gtgtttccag aatttaaaat caatcgatga acttttttag
    31201 ggaagctgct ggcaaatacc agtgctagat ttgctccatc actaaatcca agaaaatctg
    31261 cctgatcgat tttttccagc aacatgatcg tattcagatc ctcggccatt aactgaaaat
    31321 tcaacataga tgcttcgttt gtcgaacgac catgtcctcg gctatctact agatacacgg
    31381 tatagtagcg ttcgagtaca gggacctgtt ctgaaaaaaa gcggccgctg ccgtcattgc
    31441 catgcagtaa aaagagaggg aagccttgac cgctcttttc atagtaaatt tcgctcccat
    31501 ctggcatttt tgcatatttc ttttcttttt tcacataatc acctactgtg taaagtataa
    31561 cgattatatc agtcattggg caattgtttt tactgaaaaa caacgatcat tttcgtaaga
    31621 tgtcaaaaaa tacaggaaaa ttcatttttt cttaaggcgt acacagaaat caaggaagaa
    31681 atagccaaga agataaagaa atagtaagat aaaaaaagat gtcaaaataa ctaggtgatg
    31741 aaatgaagcg aaaacgatta tctattatcc gtattctttt ttacatgatc attctgacgg
    31801 ttattggtgc ggtgttgttt ttatgaggaa gaacttatcg ttcggtaaaa cgagtggaaa
    31861 gctatcaaat agaaataaca acagctgcaa aaaattatca tatggaaaac tacgagaatt
    31921 tgatcaaggc gataatattg accgaatcaa aaggaaaagg gacagatctc atgcagagct
    31981 cggaaagtct gcatggagaa gctgagatca ttgataatcc agctgacagt attgatcaag
    32041 gtgtcaaata tttggcggaa atgatagtag aagcaaagaa acaaggatgc gatttatgga
    32101 cagctgtcca agcatataat tttgggaaag attatattgc ctatgtaaaa aatcatggcg
    32161 gagaaaacac agtagaatta gcagaagcgt attctaaaga tgtgctgagc ccacttttag
    32221 gaaatgagga agggaaacaa taccgatatt ggcggatcca gtccttgctt tacaatggcg
    32281 gctatctcta tcataatgga ggtaacatgt tttatcctga tattgtcaaa atgaatgaaa
    32341 aaataataga gacctatgaa aaagtcttta agtaaaatag caggaaatgt tcaatcatga
    32401 ataaaattaa atgaaagaag gagtgcgcaa atagtggaaa aaaggcaaaa aatggaaaat
    32461 caagaagtgg ggtacacaac caaagactgg atgttacggt ttgtgaaggg aatgtttatc
    32521 ggttcaggat ttatcttgcc aggagtcagc ggtggtgcat tagcagctgt ctttggcatg
    32581 tatgagcggc tgatttcttt tttagcccac cttacaaaaa atttcaaaga aaatgttttg
    32641 ttttttctgc ctgttggtct aggcggagtg acaggcatct ttctactttc ttttttagtc
    32701 agttttttat taggtgcgta tgaaacaacg atattatggt tttttgtcgg atgtatcgct
    32761 ggaactgttc ctgcgttatg gaaagaagca gggaaaaaag gaagagatac ttctgatgtg
    32821 atcatcatgg ttgttacttt tgttctggct tatttgtttt tattatacgg cgctcaatta
    32881 tttgacgggc aagtcgatca gaattttgga acatggctga ttgccggcgg attgattggt
    32941 ttgggtatga tcgtcccagg attgagccct tctaattttt tggtgtatat gggattgtat
    33001 aaagcgatgg ctgacggatt taaagaagta cgacttgaag tgattgtgcc gatcggaatt
    33061 ggtgggattc tttgtgttct tggattgtca aaaatcatgg attacatttt ctcaaaggca
    33121 tatagcaagc tattccattt cattttaggt gtagtttttg cttcaacgat tatgatcatt
    33181 cctaccgatt acgcgggatt gggagttgct ggggtactag cttgtcctgt tctttttata
    33241 gccggtacag cactaggttg gtggatgagc cgtttggagg aacaatataa gtaaagatag
    33301 attgataata aaaacagcac acgggtgatt caaacaaaaa ggttggcatc ttttttgtaa
    33361 aatcattcgt gtgtttttct ataaatttta taaaaacaag ttgtttttaa tcttggaaca
    33421 cgctagactt aaacacgtga ttatttttga aagttggcgg aaaatggaga aaaagaaaat
    33481 gaatggactt acacagcaag aggtagttca gaaaatggct tctggccagc aaaatgacta
    33541 ccaggaagat gcatcaaaaa gtacaaaaca aatattcagc gataatatat tgacgttatt
    33601 caattttctg aactttggta ttgggatttg tctgttattt gtaggtgcgt attccaacat
    33661 ggcgtattta gcaattattg tcgtcaatat cgttattgga atttatcaag aaatacatgc
    33721 aagaaatctt gtacggaaat tatcgattgt ttcccaatca gaagtactag tgatccggga
    33781 cggtaaagaa caatcgattt ctactaaaga gctggtatta ggagatttgg taaaaatcgg
    33841 agcaggagaa cagataccag ccgatttaca ggttatatct ggacgggcag aagcaaatga
    33901 agctcttttg acaggcgaat ctgatttgat tgtcaaagaa actggagctg aattgctttc
    33961 tggaagcttt ttgacaagcg gttctgtcat ggctgaagtt atccgagtag gtgcagataa
    34021 ttatgctgtc cgcttgacta gcgaggcaaa gactcacaaa gctattcgtt ctgaacttgt
    34081 agattcgatt cgcaaagtat ccaaattcac tagtttcgtg attattcctt tggggatcat
    34141 actatttttg gaagcactgt tcatccgcga tgcttctatc aaaatttctg ttattgcatc
    34201 tgcagcagct ttgttaggca tgcttccaaa gggtttggta ttgctaataa gtattgcatt
    34261 aacgacaggg gtaaccaaac tggcaaaaaa acgaatcctt gttcaagaca tgtattcaat
    34321 tgaaacgctg gcccatgtcg atacattatg cttggataaa acagggacca ttactgaagg
    34381 gaaaatgagt atccagcggg tagaagcact acatccgctg tacgagaaag ccatcccaga
    34441 aattatgggg acgtatctgg cagaaagcag tgataacaac atcactatgc gggctatgag
    34501 agattatttt gagctttcta atcggtatga tgtgacaaac aaagtcgcat tttcttctga
    34561 tcgcaaatgg ggcgcgatgg aatttccaga actgggagtc gtgtacgtag gagcgcctga
    34621 acgtttggtg gaagaagatc ggcttccgga cagtctaaaa acagcccaag cgaatggcta
    34681 tcgcgtactt atgttgggga tcgctccaaa tcagcaattg aacgaagaaa aaccagcatt
    34741 tgttgagccg gttgctctgt ttgaaatcga tgatccaatc cgaaaaaacg ctcaagaaac
    34801 actagcttat cttcatgagg aaggtgtgga tctgaaagtg atttctggag acaatccttt
    34861 tactgtctcc aatatcgcta gacgtgcagg attaccgaat tatgatgcgt atgtcgatct
    34921 ttctcaaatt actgaagaaa tggaagtgcg agaagctgct catcgctata cggtttttgg
    34981 acgagtgagt ccgcagcaaa agaaattgct ggtaaatgaa ttgaaagaaa gcggcagaac
    35041 ggttgcaatg acaggcgacg gtgtgaatga tgttttggcg ttaagagaag cagattgcag
    35101 cattgctatg gcagaaggtg atggagcaac acgtcagatt gcgaatctgg tattgttgga
    35161 ctctgatttt actacattgc cagaagtcct gtttgaagga cgccgagtgg tcaacaatgt
    35221 gacgaaagtc tcaggcatct tttttatcaa aacgatttat tcatttattt tatcgattat
    35281 atgtgccgtt acagcaattg gatttccgtt tatccctatc caaatcacgc tgattgattt
    35341 agcgattgaa gggtatcctt ccttcttttt atcttttgaa caagataaaa gaaaaatcac
    35401 ttaccgttat ttgcctacag cacttattaa tgctttacca aatgccttgc ttgtagtagt
    35461 gaatatcatt gcggtgtatc tacttggaaa aacattcgca tggggaaatg ctgaaactac
    35521 tactttgatg tattacttgc tgattgggat cagttgcatg gcagttgtaa aagcttgtta
    35581 tcccttcaac ccattgcgca tcttcctagc agtaacgacg atcgtaggga tatatgtagc
    35641 tgcaatgctg ttccatggaa ttttggaagt aaacttaggg ttgggagaga gcgtaggata
    35701 cttctttgta ttcatgctcg taaatattgt tcttcgagta ttgtactgga aggctgatat
    35761 tcaaaatcag ttactgaaaa gagtagcaaa ttgatgctta atgagataga aatgtgttat
    35821 acttgaaaaa gcaatgaaat atgatacaat caaacatgta taattgtgtc ctttaaaatc
    35881 gcactgattt cagttagtgc gattttttac cggttattct cctgaaatat cttctgttaa
    35941 acccaaaaga tatcaataga gcagggggtg aaaaaatggc tcaacggatt cctcaagagg
    36001 ttatcgaaac agtacgcagt caaacgaata tcgttgaggt gattggacaa tatgtccagt
    36061 tgaaaaagtc tggtaaaaat tacttggggc tgtgtccttt tcatgaagaa cgtacaccgt
    36121 ctttttctgt tgcagaagac aagcagattt ttcattgctt tggttgtggt aaaggcggaa
    36181 acgtgtttac ttttcttcaa gaactagaag gtctaagttt tccagaagca gtggtaaaag
    36241 tggcagactt cgaacagata ccgttagaag atcaatggcg tcagcgtact atagctgtcc
    36301 aaaatcctga atctgctacg gggaaactga ttgctgctca tgaaaaagca gcggaaatct
    36361 atcatcacat gctattgcat acaaaagctg gacagccagc tttagaatat ttgcaaagtc
    36421 gtgggttgtc tttagaatta attgaagaat tcaacatagg ttttgcacct aatgagcgtt
    36481 cttttcttca gcaagtattc aagaatgaat caatttcaaa tgaattgtta gaacgctctg
    36541 gattgtttgt cacgcatgat gatggccgta tgtctgatcg tttttatcaa agagtgatgt
    36601 ttccacttcg taattctcaa ggccagacga tcggtttttc aggacgctgg cttgcacctg
    36661 aaaaagggca ggaaaaagat cagcccaaat acttgaatag tccagaaaca gaactgttca
    36721 ataaaagaca agttttattt aatcttgata aagcaagaag cgatatccgg aaaaacggag
    36781 aaattttgtt gttcgaaggg tttatggatg tgattgctgc atggcaggct ggtatcaaaa
    36841 ctggattagc ttctatgggg acaagtctaa cagctcaaca gatccaacaa atggaaaagc
    36901 tgacgaaaga attggtcttt tgctatgacg gagacaacgc aggttttgaa gcaaccaatc
    36961 gagggattga attgcttcgg caaaacagtc gattagcact ttctgtcgta gtcgttccag
    37021 aaaagcttga tcctgatgaa tatctccgta agtatggaga agcatctttc caagaattag
    37081 tggctcatgg gcgcgaaaca gtctttactt ttaaatcacg ttatttaaaa caagggaaaa
    37141 atttagataa tgaaaaagac aagatcgaat acctcgaaga attactagtt gaacttagcc
    37201 gagttgtttc accaatcgaa caagatatgt atctatctca actgtcaaca gagtttcaga
    37261 tcggcagaga gacgatacaa aaacaactgc gcgatcttcg aaggacaaat cagcaaaatc
    37321 gtcaagaacc tcaggaaagt caacacactc aggttacgag acaagaaact gcacggaaaa
    37381 agagaccttt gacgcaagta gaaaaggcag agcagattct attatatcgt gcatttaaag
    37441 aagtttctgt ccgtaatatt ttaaaagaac gagaatttca gtttattcat gatgcatatg
    37501 cagaagttta ttttttattc gatgcatatg tctcacaaca ttatgaattc aaccttgcag
    37561 agtttttaga ctttttgcaa gatgaaaatt taaggcggtt ggtggtggaa atcgaatatt
    37621 taccggtggc agaagaaagt tcgccacgag aaatccaaga cttgctagat gtgatcagca
    37681 aatctggctt agctgatgaa ataacattaa aaaaacaaat gcagcaagaa gccagacgaa
    37741 ctggaaacaa acagcttgag cttgaattga cgattgaaat catcaattta acgaaacagt
    37801 taaaacaagc caaatagcta ctcaaggggg gccttctttt atggcaaatg gaacagataa
    37861 aaaaacgtat gaagcagcag tagcagcttt catcaaagaa aacaaaccca aacgacaagt
    37921 tgtatatgat gatttatcca atcagcttgc tacaccattc actttgaatg cagatgaaat
    37981 ggacaaattg atccaaaaga ttgaagacgc aggtatcagt gtggtggatg aaaatggtga
    38041 tccatcaatt cacagcttga agagtgctga gaaaaaagct gaacaagcaa aaacagaaga
    38101 tctttctgcg ccaaccggtg taaaaatcaa tgacccggtt cgtatgtatc tgaaagaaat
    38161 tggccgtgtc tcccttttaa ctgcggaaga agaagtagcg ttagcattga aaatcgaaga
    38221 aggcgaccaa gaagcgaaac agcgtctggc agaagcaaac cttcgtttag tagtaagtat
    38281 cgctaaacgt tatgtaggac gaggcatgca gttccttgac ttgatccaag aaggaaacat
    38341 gggactgatg aaggcagttg aaaaatttga ctaccgcaaa ggatttaagt tttcaaccta
    38401 tgctacatgg tggattcgtc aagccatcac tcgagcaatc gctgaccaag cacgtacgat
    38461 ccgtattcca gttcatatgg ttgaaacaat taataaattg atacgtatcc aacgtcaatt
    38521 gctgcaagac cttggaagag aacctacgcc agaagaaatc ggtgcggaaa tggatcttcc
    38581 aacagaaaaa gtccgagaaa tcttgaaaat cgcgcaagaa cctgtttccc ttgaaacgcc
    38641 aatcggtgaa gaagatgact ctcacttagg tgatttcata gaagaccagg aagcaacaag
    38701 tccagcagaa cacgcagctt atgagttact aaaagaacaa ttggaagatg tactagatac
    38761 attgactgat cgggaagaga atgtccttcg cttacgtttt ggtttagatg atggccggac
    38821 gagaacattg gaagaagtag ggaaagtatt tggtgttact cgggaacgta ttcgtcagat
    38881 cgaggctaaa gcattaagaa aattgcgcca tccttctcgt tcaaaacaat taaaagattt
    38941 cttagaataa gcgtggacta ttgaccagaa gagaaatcag taaaactgtt tggtttattt
    39001 taaaagaaaa aaagcttgag actacgcagt ctcaagcttt tttttctata ggaaggaaat
    39061 tcattcatta tttttaagta aatcctaaaa ataagctatt ggcgtgacgt atagaatatg
    39121 atagattaaa tggtagcgta aacctagtaa aggagccgat cgctaagtga tgaaaaaatg
    39181 tccaaattgc ggatcgaaaa aaatggagca gaatactatc tgtccagact gcggtcatca
    39241 aataactgca gaagatcagc aaataaaaga atcaattgaa gaaacaaata cagatgcagc
    39301 tatgcaggat aaatcaactg aagatgcagt ctttcctgat acagaattaa acgatccaat
    39361 cgaatggtcg gaattgaaag atttacctct agaatctgta atggaattat tcgaaaaagc
    39421 agaaccagaa gacgaagaac cacctgctca cgatcaagta actaatatag agaaaaatga
    39481 acagaagaaa gcaactgttc atgagacttc ggaagaatca ggaaagaatc aagaagaaac
    39541 gcttgaatca aaacaaaaaa gaagagtagc tgaactgaaa gaaatcgtcg ataatgagga
    39601 agaaaattcg atactatccg cttatatcaa agcacatcgt gaagatacaa aagaagagca
    39661 cgcgaaagag ctgctcaaaa tgatcagtga aaaaattgca caggaaaaca aagtagagcc
    39721 agaaaaggaa caagaaactg aaaaagactc tgatagagaa aacgccacag gtaaagaaac
    39781 agtaaaaata aaagacgtaa aaacggatat cacagaaaaa actgaagtat ttactgaaaa
    39841 acaattagaa aaggaaaaaa cgaataaact gccggaagca gagaaaaaag aaatactcga
    39901 aaacacagac aaaaagtcaa cagagcccga tgaaataaat agtgaatccg atgctgaaaa
    39961 tcaatctgta agcaaagagg gtactgatct tgaagcaaaa atagaaaaag aagagaacca
    40021 gcctaagctg tttgaagcag aagcgaaatc aataacaatc gtgccagata ctgaaaaaac
    40081 acatcaagaa tcaaacttag aaaaaacaga tccagataaa gcgcaaaaga aaaaatcaaa
    40141 aaaagtacct tatctcgttt tagcagcagt acttctactc ggtggaggaa gctgggctta
    40201 ttatgaccat catcaaaaag tagaagccga agtagcagca gaagcaaaaa gacagcaaca
    40261 aatggaagaa cttcatgaga aacttgctgc cttttataca gatgatcacc atcaatttat
    40321 tcgtgcagat atgattcatc aagatttatc aaaactaaaa aatgatttat ccagtcttaa
    40381 gaatgaaaaa ggatattcag agttagaaac aacttaccaa gatatccaat ctaagatccg
    40441 agatatccaa aaagtgaatg agtggttcat agcacctgcc atcgtcgatg atcatctagc
    40501 agatgacatc aagttgaaag cagataaaga gatccaagca atcgaaacgg ataacacaga
    40561 ttttggaaaa ttgattcaac aagcacaaac agaagctaaa aatcaatatg ctgaattgca
    40621 aacagctaaa gaaaaaacag ctatagtctt taaagacgga aaagtagtgg attcagcaac
    40681 acgcgaccaa tacaagacgg caaaagaagc agtagaaaaa gtgaaaaata cagatctatc
    40741 tgctcagttg aatgaacaat tgaaacaagt agataagatg ctcactgata aagagaaaaa
    40801 agaagaagag gaaaagaaaa aagcagaaga agcgaaaaaa gcagctgaag aacaagcaaa
    40861 acaagccgct caagcagcag ctgcagctca agccgctcaa caagctgcgg tcgcacaagc
    40921 agcacagcaa gaagcggcat cctcgacccc ttcctcttca aactcagcga atcagccaat
    40981 caaatctgcc agagcaagtg atattgccga tgcatctaat ccagcatgga cgtgggcacc
    41041 aggtgtccaa agcaaagtga ttgctacatg tatccaacgt ggatatatcg ttgaaggagg
    41101 ttacagatta gaaaaagcca gaatcgaaaa tggggaaggc tattataatc tatatgccac
    41161 ttcaacaaaa tctgcattga tgaaaggcat tggagaaagt gctttgccat tttacatcgt
    41221 aaccatcaac tgtaaaactg gatggttcgg aggaaatggg agcaattaat tttaggcaaa
    41281 tgaaagaggc tgtgagcctg ccgtttaaca ccgtttattc gaaaaagggg agtatgacac
    41341 aactgttgtc atactccttt tttcaccttt ccaaaccaag gctcagctat tcaagtagat
    41401 aacattatgt tatgatagca aagaaatgta ttaagaaaac ctttcactat agagggagaa
    41461 aaaaatgaac gatttattag caactatatt tacaggtatt attattgatg aaaatgaaaa
    41521 aaactacttt gtccaaaaaa acggacaaac ctttggctta agcaaatcag aaggtgaaca
    41581 caaaatcggt gaagcagttg aaggattcgg ttaccaaaat caaaaacatg aaaatcggat
    41641 cactacacaa attcctaaaa gccgtatcgg tcattacgct tttggaatcg ttactgctac
    41701 acgaaaagat ttaggtgcgt ttgtcgatat cggtcttcca gataaagact ttgtcgtatc
    41761 tcttgatgaa ttgccgacaa tgacagagct atggcctaaa aaaggggatc gcttgatgat
    41821 ttcccttaga gttgatgcaa aagaccgtat ttggggcagt ttagcagatg aaaaaatatt
    41881 caaatcttta agcaaatatg gaacagaaga aatgaaaaac aaagatgtga taggaacagc
    41941 ataccgcttg aaattaacag gtacgtacgt tttaacggaa gatttctatc ttgggtttat
    42001 ccatccttct gaacgatata atgaacctcg tctaggcgag cagataaaag gtcgagtgat
    42061 tggtgtccga ccagacggtg tactgaatct ttcattgaag ccaagagcat atgaagctat
    42121 atcagatgat gcacaaatga ttttaaccat tttagaacgt tctgcagatc agcaaatcaa
    42181 ctttacagat aaatcggatc cagaagaaat catgaaagct tttggtatca gcaaaggagc
    42241 atttaagcgc gcattaggta atcttttgaa acaaggattg attacacaag aaaacggtgt
    42301 gacaaaacta gtcaaaaaat ctaattgaga atcccttgca tgtttttctt aactagctta
    42361 taataatttt aattaacata gtgttatatc tttttttatt tgtaattatt ataaattgtt
    42421 ggggttgagt aaatggtcat gaatgctatt tcggcgatga aaaaaacaaa acagcagcta
    42481 catgaagcgg ggtttaagct gacaccgcaa agagaagcta ctctgcttgt gcttttggaa
    42541 aatgagaaag agcatttatc tgcagaagaa atcttctttt tagtgaaaaa aaagagtccg
    42601 gaaattggac ttgctactgt ttatcgaacc cttgaaatct tgacagaatt gaaaattgtc
    42661 gataaagtaa gttttaatga tggattagcc cgttatgatt tgagaaaaga aggcgccaaa
    42721 catttccatc atcatttact atgcttgaac tgcggcacga tcgaggaagt agaagaggat
    42781 cttttacttg aagtggagca agtagtagaa gaacgttatc attttttagt aaaagatcat
    42841 cggctaacgt tccatggaat ctgtcaggaa tgctatgaaa aagaaa
//
LOCUS       DAFBVQ010000015        42306 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.015, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000015 DAFBVQ010000000
VERSION     DAFBVQ010000015.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 42306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 42306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..42306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.015"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(23..391)
                     /locus_tag="LLC22_001028"
     CDS             complement(23..391)
                     /locus_tag="LLC22_001028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactoylglutathione lyase"
                     /protein_id="HBK5434322.1"
                     /translation="MFTNEIKIMLYVDDVEKNATFWRAVGFAEKDRQEMDGTLIIEVG
                     VEDSQTSFLLYDRAFVESHSPGTATSAPSLMFYSKDIFGLYKKMQTQSVTLGDMVQLG
                     EEYVFNFADPDGNYFAVTGK"
     gene            complement(1002..2393)
                     /locus_tag="LLC22_001029"
     CDS             complement(1002..2393)
                     /locus_tag="LLC22_001029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-cystine transporter"
                     /protein_id="HBK5434323.1"
                     /translation="MTTLITVLVVLVFAALLYVFYRMQKRHTKFSTRVFTALGVGIVF
                     GGLLQLIFGVDDKVVTQSMEWIGIVGQGYVSFLQMLVMPLVFISIIGAFTKMKVSEKL
                     GKISATVLTSLLGTTAIAALIGIGSTMLFGLQGAKFTQGAAETARISELATRQETVEN
                     LSIPQQILSFIPKNVFADLAGSRATSTIGVVIFAAFVGIAYLGVKRKAPKEAAFFSDL
                     VDSLYKIIMRIVTLVLRLTPYGVFALMTNVLATSDFAAIVNLGKFVVASYVALLAVLI
                     VHSLILIGAKVNPINYFKKAFPVLSFAFTSRSSAGALPLNIETQTKALGVDDATANFS
                     ASFGLSIGQNGCAGVYPAMLATIVAPAAGVNVFSLEFILMLVAIVTISSFGVAGVGGG
                     ATFASLIVLGAMNLPVAIVGLVISVEPLIDMARTAVNVSGSMVAGIVTSARIKDLDRD
                     VINDDSKVIDVNA"
     gene            complement(2606..2992)
                     /locus_tag="LLC22_001030"
     CDS             complement(2606..2992)
                     /locus_tag="LLC22_001030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1149 family protein"
                     /protein_id="HBK5434324.1"
                     /translation="MEIRRQKEVVEAFHYDMRLPNQEVETDLKVGFSPLKETIENYPK
                     EHSIVGARLEFRLVFDTYVLSGSVSQINHILNRKIEGQNDVTQEEVDELVAPLFDIVR
                     RMSYEVTEIALDQPGVKLNFQSEKQE"
     gene            complement(3048..3671)
                     /locus_tag="LLC22_001031"
     CDS             complement(3048..3671)
                     /locus_tag="LLC22_001031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IA family hydrolase"
                     /protein_id="HBK5434325.1"
                     /translation="MKNYIWDFDGTLFDTYPAMVDGAWQALKDFGISMDKKEIYFKMK
                     KYSTSYLINESNLNAREFNELFHRYEKESTEVSRPFPETKQVLEMLKDNGGRHFILTH
                     RLTESTWGLLKEHRLAHLIEEVVGIDQDFPRKPDPASLNYLIDTFHLERTDTMMIGDR
                     RLDIEAGKNAGVATCLYDIDHFLGEIPADYVVGNLNEILTLQSIIKK"
     gene            complement(3735..4403)
                     /locus_tag="LLC22_001032"
     CDS             complement(3735..4403)
                     /locus_tag="LLC22_001032"
                     /EC_number="5.4.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3-bisphosphoglycerate-dependent
                     phosphoglycerate mutase"
                     /protein_id="HBK5434326.1"
                     /translation="MKLVLLRHGESEANFENYWTGWLDVALTEKGKEQAAVAGQKMLE
                     AGLQFDAVYTSVLKRAILTGQVALEEMGQLWLPIIKTWRLNERHYGDLVGKNKDKMKE
                     IYGKDQVKTWRRGYTEVPPLTAENRFDRRYDHLDPHLIPYGESLEMTVNRIIPLWQDH
                     LAPKLKDRQDLLVVGHGNSIRALTKYLEDVPEDQMDTIDIPNAQPIQYTLADDLTILD
                     KKIL"
     gene            complement(4415..4855)
                     /locus_tag="LLC22_001033"
     CDS             complement(4415..4855)
                     /locus_tag="LLC22_001033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434327.1"
                     /translation="MMQTWLERLIRFQQNYHKLMQGRYAKFDQLNRGLLIAALVFSLL
                     SRWLPYRIGQLLFIVFFGWMIFRFLSKKIYPRLNENQRYLKYLDRVKEKYHQIKNKKQ
                     VKMDRKSYTFFECPNCHQKQRAPKGKGRIRVTCKTCGIKFETNV"
     gene            complement(4914..5585)
                     /locus_tag="LLC22_001034"
                     /pseudo
     CDS             complement(4914..5585)
                     /locus_tag="LLC22_001034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327855.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(5770..6168)
                     /locus_tag="LLC22_001035"
     CDS             complement(5770..6168)
                     /locus_tag="LLC22_001035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="P-II family nitrogen regulator"
                     /protein_id="HBK5434328.1"
                     /translation="MKDLVALNLHMIVTIVDGGMGEDVIDFSKEAGAAGGTILHGRGS
                     GVHDSGKFLGLDISPEKDIVLTLVPDSLTNKVMDAIGQGINIDIPGNGICFSIDVDKV
                     IGITKIHQYREIIGMQELLDENNDREKSES"
     gene            complement(6165..6938)
                     /locus_tag="LLC22_001036"
     CDS             complement(6165..6938)
                     /locus_tag="LLC22_001036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBK5434329.1"
                     /translation="MSFWQQVIDGIEIVTMEVILAVAPIVILFVLMNIISFRMRKKRF
                     FDIMKGFLITTIGLILFLHGVNMAYVPVGQHLGSAIAGLPYNYILVPLGFLMGFLVGF
                     AEPAIHVMIKQVEELSEGRIRSKIMLMVISIGIGAAVGLSMWRLLVGFSLYYFLIPGY
                     GLAFILGRKVDKIFLAMAFDNGGVATGPMCSTFILSMSVAIAAQIEGRDPIIDGFGVV
                     AMIALTPILSTLVLGYIYKRKDEKDRIEKERLQKLGESK"
     gene            complement(6935..7618)
                     /locus_tag="LLC22_001037"
     CDS             complement(6935..7618)
                     /locus_tag="LLC22_001037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1538 domain-containing protein"
                     /protein_id="HBK5434330.1"
                     /translation="MLKNFKEVIAAILPMTVLIVILTFVFAPLEGEDLASFLVGAAIM
                     MIGMTLFLFGADYSMMEVGDLVGKYMIKKKSLTVLVSLGFAIGIVITIAEPSVQVLGQ
                     QVYDISDGEIGRVLLIGIVSVGTGVFLAFALLRVVFKLSYYQLMAIGYIGVLIASFFT
                     SSEFMPIAFDSGGVTTGPVTVPFILALAGGMTSMIKQKKNENDSFGMVGIASLGPILA
                     VMILGVIFQ"
     gene            complement(7785..8672)
                     /locus_tag="LLC22_001038"
     CDS             complement(7785..8672)
                     /locus_tag="LLC22_001038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5434331.1"
                     /translation="MKNMVEKETIERPNVKKQALELRSTIGSVLKYTALSILSFISIF
                     PFVWMVLGMTNTPVDITSGKIKIGSNLIINFQNLFSNELNFTRSLWNSAMIALVTTVF
                     ALLISSMAGYGFEIYQSKRKDLIFNILLLSMMVPFAALMIPLYRMFSQLNGTVLGINS
                     FLVVILPSVSTAFLIFFFRQNVKSFPKDLVEAARLDGLKELSIFFRVYMPTAKNTYAA
                     AAIITFMSSWNNYLWPLVALQSPDKRTVPLVLSAMGASYTPDYGMIMAGLVIATLPTA
                     IVFFVLQKQFVQGMIGSVK"
     gene            complement(8669..9538)
                     /locus_tag="LLC22_001039"
     CDS             complement(8669..9538)
                     /locus_tag="LLC22_001039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5434332.1"
                     /translation="MKQKDLFKNGHAFLILPVILISIMVFIPMVLALITSFQSGPPVN
                     MTFNGLGNYQRMLTDATFKKAFFNTFLYLLVQVPIMLFLALFISNLLNDKKLKYKGLF
                     RTAIFLPCITSMVSYSLIMKSLFSQSGLVNNLLLGIGMIDTPIGWLTHPIWARVLIIL
                     SITWRWTGYNMIFFLSGMQNIDSEIYEAASIDGASKWQQFIKVTIPNLKPIILFTSIT
                     STIGTLQLFDEVQNITGGGPANATTTLSQYIYNLSYKFTPNFGYAAAVSFVIVSFIVI
                     LSIIQTKVGGESR"
     gene            complement(9675..10961)
                     /locus_tag="LLC22_001040"
     CDS             complement(9675..10961)
                     /locus_tag="LLC22_001040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5434333.1"
                     /translation="MNIRKLIAGVVCLAAASGFLTGCGSASSTADKEEKVTVWAWDET
                     FNIKAVNEAKKVYENEETEIEVVTMSQDDIVQKLNTALASGNTEGLPNIVLIEDYRIQ
                     GYLTSYPDAFANLSAIVKEDHFAPYKFAVNKVGDKIYGVPFDSGVTANFYRTDLMAEA
                     GYTEEDMENLKWDEYIQVARDVKEKTGKKIAEVNPSDLGRVRMIMQQAGEWYTSEDGE
                     TVTIQDNASLKYGLELFATLLKEDLVEQTSDWNAGVTAIQSGAVASSPTGAWYSSTIQ
                     GAENQSGKWKIAPIPALPENLQKAQASNLGGAGWYVIKGVAGEDSAKDFLEATFASNE
                     ELMGTLAKEIGLVSTMLSANEQEAYQEASEFYSGQKIFDDFSTWTSEIPEVNYGHETY
                     AIEAVVAEALHRIINGEETDKVLADTQKQVEAQLAN"
     gene            11234..11812
                     /locus_tag="LLC22_001041"
     CDS             11234..11812
                     /locus_tag="LLC22_001041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator"
                     /protein_id="HBK5434334.1"
                     /translation="MPIRVILIDDEQTILDGMKQLINWSEHGFQLIGTFSSPLKALDF
                     SLVHAIDIVVTDVMMPELNGIELSRLLKQQQPETQILILSSYDEFDMVKDSFKEGVAD
                     YLLKPRLSPDFFLNSLTAVSQKIKKKPNKSPITNRYEQICENLSQQIAGQTRPLLDPL
                     LFEHTLFFCYIPKNGHSVQNKALNKNSRSPIH"
     gene            11812..12741
                     /locus_tag="LLC22_001042"
     CDS             11812..12741
                     /locus_tag="LLC22_001042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5434335.1"
                     /translation="MDSDDSFTIYPVSTFSEESGYVINTDSKDTLRKFVQKFRQEVFP
                     GDFFVVSDSFAIQDINEIFQEIRNCTKGQRFYHKGKNLAYQHELLPLLTNHEQQASSY
                     LTKIVHKDYALAVKELENFFTTILEQPIDPAYLKHEAINRFYALLNALADEHVGNEEL
                     SLLKIALPSLLADAEYFEDFSILVKETLEKLTHFSANAKKDNFDILTLIYEFVQENYE
                     KEINLQLLSEKYHFSYSYLSAIFTEKFGINFSKYLKKVRISKAKLFLTETRLTLTEIC
                     EKVGYTELGYFSRVFKEETGMTPSQYRKGTFVK"
     gene            12738..14474
                     /locus_tag="LLC22_001043"
     CDS             12738..14474
                     /locus_tag="LLC22_001043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine kinase"
                     /protein_id="HBK5434336.1"
                     /translation="MRKKIKEHELFAKLLFILFIGLFLQAIVISLFIYHRSRDAYIQL
                     FNQSNDVVLKKIQSEFESLNDTIENTLAAFDSNPAVKSYFSNDPAQHMEQLQQLRTIQ
                     KMNDSLSKIHPMIDYDVLIFGENGRTFVGNDMLTAVSADSFFQSAIAQRVNERAADTQ
                     MLFAHHGLTLRDKKAPSVFFVKKLKNTLNHVYGYAVLSISSKQLANLFQSVVNPEISK
                     ISFMNEEQTIIASNEENTIGSRSMIFKKLTVGETTISNGQQLTRLPLYRQDCTLLSQV
                     DLHSLSNQMGVIFPIILYNIVTLAFAGSLVFMYLDRHTKSIYRLIDSLKRLEEDGLKA
                     TVPVQGSHEVQLLGNTINQLLSNAQHHYEQTIQDEKKKRSLEIQTMQAQIQPHFIYNT
                     LTSLKFLIWQKKTDEAVQGIDSFITLLRSTIGKKEEVIPVKEEIKSVQSYIDLLSMRY
                     GERISAKIMIPDELQSLSMPNMILQPIIENAYLHAFHNKTQGFITVYGKTKNQLLLFE
                     VIDNGDGFDTENTKQKNDHFSGIGISHVDERIRLMYGDAYGLTIQSVIGTGTTVTICL
                     PLLPKNQSEYQK"
     gene            complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="LLC22_001044"
     CDS             complement(14537..15373)
                     /gene="pheA"
                     /locus_tag="LLC22_001044"
                     /EC_number="4.2.1.51"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydratase"
                     /protein_id="HBK5434337.1"
                     /translation="MNVSYLGPESSFTYQAACQLFPTEQLTAYASIPVCLRALFRKQV
                     DLAVVPVENSLEGAVHHTIDLLSKHPEVEVKSEIVLPIKQQLLGNPATKITKILSHPQ
                     ALAQSQQFLETHYPNVPLVATESTTAAAMYVAEHPKEDAAAIASLETAQHVGLEILAE
                     NIQDNELNQTRFWIVGDRKMTSQQSAPVKMSVILTLPANRPGMLHKMLAAFGWREINL
                     SKIESRPLKTSLGEYFFVIDLLLDRPMTLVENALQEIKMLGGESQILGCYPVLTVEET
                     RR"
     gene            complement(15370..15879)
                     /locus_tag="LLC22_001045"
     CDS             complement(15370..15879)
                     /locus_tag="LLC22_001045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="shikimate kinase"
                     /protein_id="HBK5434338.1"
                     /translation="MASILLIGFMGAGKTTIGKGLAQCLQKEYVDLDTKIEEHIQLSI
                     AEYFHYYGEKSFRKVESDILRKLSNEDKIIATGGGIVQSAENRRFLKTQPIVLYLEAE
                     ADCLVDRIQQDETSIRPLALGKTREEIKALLAQRLSWYEESATHRINTTNQTPEKIID
                     TIIERIKSI"
     gene            complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="LLC22_001046"
     CDS             complement(15872..17167)
                     /gene="aroA"
                     /locus_tag="LLC22_001046"
                     /EC_number="2.5.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-phosphoshikimate 1-carboxyvinyltransferase"
                     /protein_id="HBK5434339.1"
                     /translation="MQLLQQIHGLRGTVRIPADKSISHRCIMFGAIAEGTTTIQNFLR
                     AEDCLSTLHAFQQLGVEIEEEEEVIKIHGRGSHSFVQPTESIDMGNSGTTIRLLMGIL
                     AGQPFTTTLFGDASLSKRPMGRVMEPLREMGADLQGEENDQYLPITVTGTRSLSPIRY
                     NMPVASAQVKSALLFAALQAEGTSVIVEKERSRNHTEEMIRQFGGRITVEDKTIIVTG
                     PQKLTGQQITVPGDISSAAFFLAAGLLVPESQLLLKNVGVNPTRTGILDVLEEMGAAI
                     TQTNHNEQNQSADLSVKTSHLKKATIGGEIIPRLIDELPILALVATQAEGITIIKDAE
                     ELKVKETNRIDAVAEELQKMGAKIKATADGLIIHGPTPLHGAKVSSRGDHRIGMMLQV
                     AALIADGPCELEGAEAVSISYPAFFDDLAELVSGGEAHG"
     gene            complement(17180..18271)
                     /locus_tag="LLC22_001047"
     CDS             complement(17180..18271)
                     /locus_tag="LLC22_001047"
                     /EC_number="1.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prephenate dehydrogenase"
                     /protein_id="HBK5434340.1"
                     /translation="MAQHVFIVGLGLIGASMALCIRQTNPELIVVGWDSQSKTREQAV
                     EQQIVDYVASDFETGAEQADVILLAVPVRTTLAYLDVLERINLSDHVIITDVSSTKQQ
                     VVTSAEQKNLRFVGGHPMAGSHKSGIQAADAKLFENAYYIFTPLEKTKKDVEKLQELF
                     CGTKAKYVTLTAREHDRITGMLSHFPHILAAGLVNQAEQFNQEYPRAKQLAAGGFRDI
                     TRIASSDPVMWTDILLSNKQILLERLADWQQEMTQIAEWIMTENQSEIFSFFNRAKES
                     RDQLPVHKQGAIPAFFDLFIDVPDEPGVIAEVTGLIGKAGVSLINLKIQETREDILGI
                     LQISFKNQQDLLQAKRIIMSNTSYHCWIK"
     gene            complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="LLC22_001048"
     CDS             complement(18288..19454)
                     /gene="aroC"
                     /locus_tag="LLC22_001048"
                     /EC_number="4.2.3.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001269368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate synthase"
                     /protein_id="HBK5434341.1"
                     /translation="MRYMTAGESHGPELTAIIEGLPAGLPLSEEEINHELARRQAGYG
                     RGGRMKIEKDRVRITSGIRHGKTIGSPVTLVVENKDWKNWTTVMSVAEVPEKDQSLRR
                     VARPRPGHADLVGGMKYHHRDLRNVLERSSARETTMRVAIGAIAKKILEELDIIVAGH
                     VICLGGIQAEIPGNISIQEIKEISEASEVRVVDPAVEQRIKDLIDQTKKNGDTIGGIV
                     EVLVGGVPAGLGSYVQWDTKLDAKIAQAVVSINAFKGVEFGVGFTSGSLPGSEVMDEI
                     LWEEERGYFRRTNNLGGFEGGMTNGEPLVIRGVMKPIPTLYKPLQSVDIDTKEPYKAS
                     VERSDSTAVPAASVVAENVVATVVATELLSKFPSDSLVELKAAVKEYRDYLKHY"
     gene            complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="LLC22_001049"
     CDS             complement(19456..20520)
                     /gene="aroB"
                     /locus_tag="LLC22_001049"
                     /EC_number="4.2.3.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-dehydroquinate synthase"
                     /protein_id="HBK5434342.1"
                     /translation="MLTVHVDNQKYDIHIEKGALEQAGSWLQTIWRPQKVAVITDTNV
                     APLYAEKIMFQLRQANFEPVLSIVPAGETSKSLEQAAELYDFLADNDFTRSDGILALG
                     GGMVGDLAAFVASTFMRGIHFVQIPTTLLAQVDSSIGGKTAVNTNKAKNLVGTFSQPA
                     GVLIDPEVLKTLPVRRLREGIAEIIKSAAIADATLWKQLNELKDEKDLLEHAVPIITA
                     TLEIKRKVVEEDVFDQGNRLILNFGHTIGHAIENTAGYGVVSHGEGVAIGMVAITSHA
                     EKIGLSPTGSTAALERILQKFHLPITYDLSHPDELFHAITHDKKARGSQLNIILLEKI
                     GQAKIVPVPTETFKDYLGGL"
     gene            complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="LLC22_001050"
     CDS             complement(20553..21575)
                     /gene="aroF"
                     /locus_tag="LLC22_001050"
                     /EC_number="2.5.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-deoxy-7-phosphoheptulonate synthase"
                     /protein_id="HBK5434343.1"
                     /translation="MIVIMKKEATEEQIKKVVDHIEKEGFKVSIDQGTERVVIGLKGD
                     TRSLQEGAFTRYEGVENAVRILNTYKLTSREFHPGNTVVDVDGVKIGDGSFVTMAGPC
                     SIEGLDQIRECARMAKAGGAKILRGGAFKPRTSPYAFQGLEEEGLKYIRQAADEFGMK
                     VITEVMDEGHIDMVAEYSDILQIGARNMQNFKLLSAVGKTGKPVGLKRGISGTINEWL
                     NAAEYIAVEDKSPVIFIERGIRTYETATRNTFDLSAVPLMKKLTHFPVIVDPSHGTGI
                     WELVPPMARAGVASGADGMIVEIHPDPANAWSDGPQSLNEKTYSRMMKEVAIMKEAME
                     KIQTLD"
     gene            complement(22234..23208)
                     /locus_tag="LLC22_001051"
     CDS             complement(22234..23208)
                     /locus_tag="LLC22_001051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase small subunit"
                     /protein_id="HBK5434344.1"
                     /translation="MKNTVNKSHMDTEKVAIVFGDCTLGVKSGNTHYIFSYTRGGLES
                     LNKNGKEWLYRETLPVFWRATTDNDRGSGFGFKSGMWLGAGLYPKVKEIEVLVDNKKI
                     DLPIAPVNNQYSSNEYAETVEIIFTLEINTVPKTQVTISYQIAGEGKMLVNMHYYGQK
                     GLPELPALGLRFIMPTKAKFFEYEGLSGETYPDRMAGGVEGIYKVAGLPVSPYLVPQE
                     CGMHMETKWVELTRNQTLDNTDKDQEDFSLRFEQQDTPFAFSALPFKAEELEQATHIE
                     ELPPERRTVLTIFAKVRGVGGINSWGADVESPYRISSEEDHEIGFIIQ"
     gene            complement(23189..25072)
                     /locus_tag="LLC22_001052"
     CDS             complement(23189..25072)
                     /locus_tag="LLC22_001052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-galactosidase"
                     /protein_id="HBK5434345.1"
                     /translation="MKANIKWLDDPQVFRVNQSNAHSDHVCYATREEVETRSSLKQSL
                     NGSWRFCYSPNPSVRPKTFYKKDFDACSFDEITVPSHIELANYDKIHYINTMYPWEGH
                     VFRRPPFTTSPEKEAEGIFSAAKDNPVGSYLTTFRLEEGLKGKQISIHFAGVEQAMFI
                     WLNGHFIGYAEDSFTPSEFDLTPYLEEENILAVEVYKRSTAAFLEDQDFFRFFGIFRD
                     VFLVARGQNHLEDLWIKPRLDDKCQNGKLEVDLSFEQVAKNSQLNVAILDPDGKEIYQ
                     QQYPLKEQMTIRIDGFENVALWGHFQPNLYKLELETIDEEKRVTEYIDYSFGFRKIEI
                     KDKIIYFNGKRMIINGVNRHEWHPKKGRAITIEDMEKDLAIIKNAKINGVRTSHYPNQ
                     ITWYYLCDQAGIHVMAETNLESHGSWQKMGAFEPSYNVPGAVPQWQAAVLDRAKTNFE
                     TLKNHPSILFWSLGNESYAEENIRQMNDYFKKVDPDRLVHYEGNFPNPAFEDSISDVK
                     SCMYAPPEEIIDYLENKAEKPFILCEYMHDMGNSLGGMDSYMTLLDRYEMYQGGYIWD
                     FKDQAIQVTDPITGREVMRYGGDFDDKPSDYEFSGNGIVFADGQEKPAMQEVRYYYEK
                     YSK"
     gene            complement(25090..27315)
                     /locus_tag="LLC22_001053"
     CDS             complement(25090..27315)
                     /locus_tag="LLC22_001053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-galactosidase"
                     /protein_id="HBK5434346.1"
                     /translation="MDITHRKTDKNFILFDEKSRVFHLRNTFLSYLIKIEESNVLAHI
                     YFGKPVKQYKDNKNYPRRDRGFSGNVPLNPDRSLSKDTLPQEYSSHGSMDFRTPASII
                     QRKNGSDLLDLRYDSHYITDGKPEIEGLPQTYVMDKSEAQTLVISLKDRETAIYFDLF
                     YTIFTDRAVITRSVKIRNETGETIKLEKAASFQLDFAHTRRFDEVIALPGAHVNERQI
                     SRQSVLSGTKVFESRRGTSSHHMNNFIALVHHHTTENTGEAIGLQFVYSGNHSFELEK
                     DQINQLRVVGGINSHRFSWELNAGQSFQTPEMILSYSSQGLNKMSQIHHELLRERIAR
                     GRHQFAERPILVNNWEATYFDFNSEKIKAIIDEAKELGIEMFVLDDGWFGKRDADNSS
                     LGDWFEYEGKLTNGLREIADYAHSKGLKFGLWFEPEMISVDSELYRTHPDFLMQEPGR
                     MPSASRSQHVLDFTRLDVRQTIEKQMRKILDTIPLDYIKWDMNRSLSDVYSITLDPQR
                     QGEVAHRYMLGLYELLEHLTTDYPEILWEGCSGGGGRFDAGFIYYMPQSWTSDNTDAV
                     ERMKIQYGTSLAYPISSITAHVSAVPNHQTDRSTSLKTRGETAMSAVFGYELDLTKLS
                     PEEEKQVKDQIISYQTIRPVIQYGHYYRLASPFEENIAAWMFVSPKQDEAIVFLGRIL
                     ASAQPAFHEVYLMGLDDEALYQEQTSKRIFSGAELMTVGLYFPDFQGDFQTELLHFKK
                     L"
     gene            27430..28464
                     /locus_tag="LLC22_001054"
     CDS             27430..28464
                     /locus_tag="LLC22_001054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434347.1"
                     /translation="MVGIRDVARKANVSPATVSRVLNNDQTIHVAQTTRQRIVEAAAA
                     LDYDISTRKYIKKRMPSIGVISTIGKASEEQDIYYKHLRVGMEEEARRLHLGMNRIYN
                     LSDNPKQWEDLDQLGAVIVVGTVTKESITALLKQNMQIVVVDNPDIQQEVDMVYADLE
                     RMTKTVLELFLENGHKRIAYIGGYKVDMDEFGGKQISINEKRMRAYQHFMIDHHLEKY
                     MSYHLGGWTEKQGEVLATNLLENESPLPTAILVGSDPMAIGVYRALKQKNIQIGEEIV
                     VASFDNIETIANLSPGLTSVQINAKSIGQAAVRMALERIDGIRDEPIILTYPARLIVR
                     ESFIPRTKRY"
     gene            complement(28531..29544)
                     /locus_tag="LLC22_001055"
     CDS             complement(28531..29544)
                     /locus_tag="LLC22_001055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5434348.1"
                     /translation="MKKKILKFIGWFFGIILGIAFAIFLAFQLSPRPGAFLINHMFSN
                     TVQITDKKTFDQAEKNVAKKTDLTYESKYKENTYDIYYPKNSKGPVPVLFWVHGGGFV
                     GGDKSGVKEFATKLVSDANIAVVAMNYELAPDSEYPNQVLQVNELIKDLLAEEKDDKL
                     LDMEQLFFGGDSAGSQIALQYAAIQTNDAYAKQMKIKHLLPKDSLKGTISYCGPVDLK
                     LTAQQHSDDRFMKFFVKTVAWSLIGTKDWKTSEQLKEASVADHVSKEFPPTYITDGNA
                     YSFQEQGQALENRLTELKVPVQSLFYTDTKKEITHEYQFDYTLKESQNCYQQTLDFVN
                     KYK"
     gene            complement(29622..29810)
                     /locus_tag="LLC22_001056"
     CDS             complement(29622..29810)
                     /locus_tag="LLC22_001056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine synthase"
                     /protein_id="HBK5434349.1"
                     /translation="MEEHQQVIDRIYEATRYLPLDRLCLSPQCGFASTEEENVLFEEQ
                     WKKFLLSKALQKKFGENH"
     gene            complement(30250..30378)
                     /locus_tag="LLC22_001057"
     CDS             complement(30250..30378)
                     /locus_tag="LLC22_001057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295229.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBK5434350.1"
                     /translation="MDQKEKMKELIKKKQGGGRSKQMETPKNDRKNMRKGPKIFNK"
     gene            complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="LLC22_001058"
     CDS             complement(30381..31754)
                     /gene="rlmD"
                     /locus_tag="LLC22_001058"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBK5434351.1"
                     /translation="MTEQQIVKKNERYTVEIVDLSYEGMGVAKIDGYPLFIENALPGE
                     EVEILVVKAGNKFGYGKVETFITQSPDRQPVENNALLRIGIAPLAHLKYEQQLVFKQK
                     QVEHVMAKIAKMPEVPVLPTVGMAEPFGYRNKAQIPVRRIDGQLATGFYKKNSHDLVP
                     IEDFYIQDPVIDQAIKVVRDILQRFQVRGYNEEKNEGQLRHIIIRRGHYSHEMMVVLV
                     TRKEKFFKSKEIAEAIHEELPEVVSVIQNINEEKTNVILGDKEKVLYGRDYIEDQLLG
                     KTYRISAKSFYQVNTQQAEYLYQTAIEFAELDKKDIVIDAYSGIGTIGLSLADRVDKV
                     YGMEVIPEAIEDAQFNALNNKIENVHYEVGKAEKVMKKWQEKGIKPSVIVVDPPRKGL
                     DHHFIESAIEMSPERIVYISCNPATFARDAKLFAEAGYAVKKVQPVDLFPQTHHIELV
                     ASFVKGE"
     gene            complement(31865..32920)
                     /locus_tag="LLC22_001059"
     CDS             complement(31865..32920)
                     /locus_tag="LLC22_001059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBK5434352.1"
                     /translation="MKKARVIYNPTSGKELLKKNLADILQALEEAGFEASAYATTPEP
                     DSAKNEACRVAELGFDLVVAAGGDGTINEVVNGIAPLEHRPKMAIIPAGTTNDYARAL
                     KIPRDNIKAAAEVIKKHQTVKMDIGLSDNSYFINIAAGGYLTELTYEVPSELKSIFGY
                     LAYLAKGAEMLPRVKPIKMRLKYDEGEYIGNASMFFLGLTNSVGGFEQIAPDAKLDDG
                     KFSLIIVKTANIFEILHIAALMLNGGRHVDDPRIIYTKTSSLFVETEDDINRPVMINL
                     DGEYGGEAPMHFQNLHQHIEFFANTDQIPDEAITGTDEEELEVVSKEFVKEVERLTDE
                     DIDGDGKIADETPNQKN"
     gene            complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="LLC22_001060"
     CDS             complement(32930..34360)
                     /gene="gatB"
                     /locus_tag="LLC22_001060"
                     /EC_number="6.3.5.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatB"
                     /protein_id="HBK5434353.1"
                     /translation="MNFETVIGLEVHVELKTNSKIFSPAPAHFGAEPNSNTNVIDWGY
                     PGVLPVMNKAALEFGMKAALALNCEISKDTHFDRKNYFYPDNPKAYQISQFDQPIGHD
                     GWIEIEVEGKKKKIRIERVHLEEDAGKNMHGIGGYSYVDLNRQGTPLIEIVSEADMRS
                     PEEAYAYLEALRSIIQFTEVSDVKMEEGSMRCDANISLRPYGQEEFGTKAELKNLNSL
                     SFVKKGLAFEEKRQAKVLLSGGEIQQETRRFDETTNKTVLMRVKEGSSDYRYFPEPDI
                     PKFVIDDEWIQKVKASLPEMPASRRERYIREFGLPEYDAMVLTLTKEMSDFFEAVLEN
                     GADAKQASNWLMGEVSAYLNSEKLELAETKLTPENLAGMIRLIADGTISSKIAKKVFR
                     ELITNGGEAQEVVEKNGWVQLSDPNKLLPIINEILDNNQQSVDDFKNGKDRAVGFLVG
                     QIMKATKGQANPGVVNKLLKDELAKR"
     gene            complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="LLC22_001061"
     CDS             complement(34357..35829)
                     /gene="gatA"
                     /locus_tag="LLC22_001061"
                     /EC_number="6.3.5.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatA"
                     /protein_id="HBK5434354.1"
                     /translation="MTELHNRSLEELHHMLVSKEITVQDLTKTTFERIKETEPEVEAF
                     ITLNEEKALEQAKALDEKGIDESNVLAGIPIGIKDNIVTKDILTTAASKILYNFEPIY
                     DATVMDKIYQADMIPVGKLNMDEFAMGGSTETSYFKKTKNAWDPTKVPGGSSGGSAAA
                     VAAGQIPVSLGSDTGGSIRQPAAFNGIVGMKPTYGRVSRFGLIAFASSLDQIGPMTRT
                     VKDNALALTAISGYDEKDGTSSGVSVPDFAEGLTGDIKGMKIALPKEYLGEGVAPGVK
                     EAVLKAAETFRSLGAVVEEVSLAHSKYGVAVYYIIASSEASSNLQRFDGIRYGYRSEN
                     VKSLDDVYVNSRSEGFGEEVKRRIMLGTFSLSAGYYDAYFKKAGQVRTLIKRDFEKVF
                     ADYDLIIGPSSPTVAFGIGENINDPITMYMSDILTIPVNLAGLPGMSVPAGLSEGLPV
                     GLQIIGNYFDEKTMYQAAYAFEQATEFHKQQPAILGGKDE"
     gene            complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="LLC22_001062"
     CDS             complement(35829..36134)
                     /gene="gatC"
                     /locus_tag="LLC22_001062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp-tRNA(Asn)/Glu-tRNA(Gln) amidotransferase
                     subunit GatC"
                     /protein_id="HBK5434355.1"
                     /translation="MAISEEQVKHVAKLAKLAFADEELASFTDQLGKIIDMVEMLEEV
                     DTEGVPFTSNVVETVNVMRQDRAQAGWNRDELLKNVPETEDGFIKVPAIIDNGEAGA"
     gene            complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="LLC22_001063"
     CDS             complement(36240..38276)
                     /gene="ligA"
                     /locus_tag="LLC22_001063"
                     /EC_number="6.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent DNA ligase LigA"
                     /protein_id="HBK5434356.1"
                     /translation="MEHEMTIDEAAKRAEELRTRLNQWSREYYVEDKPTVEDYVYDKE
                     YAELVAIEEQYPDLITSDSPTQRVGGKVLEGFEKVTHDIPLYSLNDVFSKEELIAFDQ
                     RVQKAVGRVVDYCCELKIDGLSVSLRYEDGNFVRGATRGDGTVGENITENLKTVRSVP
                     IKLKEPMNIEVRGECFMPKRSFVQLNQDREAEGKDIFANPRNAAAGSLRQLDSKITAK
                     RNLDTFLYTVADFGPMQAKTQYDALEELEKIGFHTNREKRLCHSIDEVWSYIEEYHDK
                     RVDLPYEIDGIVIKVNEFSLQDQLGFTIKAPRWAAAYKFPPEEVETLIENIEWTVGRT
                     GVVTPTAIMTPVRVAGTTVSRASLHNGDYIKLKDIRLKDTVLIYKAGDIIPEVSQVVL
                     DKRPKDSEEYQLPTHCPVCGSELVHLDEEVALRCINPKCPAQMKEGLNHFVSRNAMNI
                     DGLGPRVLEQMYDKKLVADVADLYKLTEEELLTLDKIKEKSANNILTAIDNSKDNSVE
                     RLIFGLGIRHVGAKAAKILAEHFGDLETLSKSDYESIIALDTIGDIIADSVVTYFSNE
                     EVHELMNELKQAGVNFEYKGLRNAQLQEVESPFKEKTVVLTGKLTRFTREEAKETIEN
                     LGGKVTGSVSKKTDIVVAGEDAGSKLTKAQELGIEVWTEDQMADALAKSRSVEE"
     gene            complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="LLC22_001064"
     CDS             complement(38293..40527)
                     /gene="pcrA"
                     /locus_tag="LLC22_001064"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase PcrA"
                     /protein_id="HBK5434357.1"
                     /translation="MSSKAELLNGMNPRQKEAVLHTDGPLLLMAGAGSGKTRVLTHRI
                     AYLIEEKEVNPWNILAITFTNKAAKEMKERVNAILASGGEDVWVSTFHSMCVRILRRD
                     VDFIGYNRNFTIIDSSEQLTLMKRILKELNIDPKKYDPRSILGTISQAKNSLQTPQDF
                     AKMQGSYYEEIAAKCYAAYQKELQYNQCMDFDDLIMNTIRLFEEHPDSLTYYQNKFHY
                     IHVDEYQDTNHAQYTLVNLLAGRFRNLCVVGDADQSIYGWRGADMQNILDFEKDYPDA
                     AVILLEQNYRSTKNILSAANQVIENNSNRKPKNLWTENKEGNKITYYRADNERDETRF
                     IVDRMQEEIRSNHRNYGDFAILYRTNAQSRVMEETLLKANIPYKMVGGHKFYDRKEIK
                     DILAYLNVLVNPQDSISFERIVNSPKRGIGPGSIEKLRSFASLHEWPLLEAAQNVDLA
                     NIGGKAGQQLGAFGEMIQEVTQMIPYLTVTELTKEVLDRSGYLEDLKIQNTLEAQARI
                     ENLEEFLTVTQEFDKQFEQQNEEDADAPEEKLTVFLNDLALVSDIDNLEEDASQVTLM
                     TLHAAKGLEFPVVFLIGLEEGVFPLSRALMEESELEEERRLAYVGITRAEEALYLTNA
                     FSRTLYGRTQYNRPSRFVEEIDQELLEIEGMRPTPKKTPVFAKKTAYSYKQPETAVVP
                     SKSATGGENNSWKPGDKVKHKKWGLGTVVRVSGTSKDLELDVAFPSQGVKRLLAAFAP
                     IEKA"
     gene            40682..42241
                     /locus_tag="LLC22_001065"
     CDS             40682..42241
                     /locus_tag="LLC22_001065"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClC family H(+)/Cl(-) exchange transporter"
                     /protein_id="HBK5434358.1"
                     /translation="MEKKGKIKKLDKTQIYFILKGIFVGLLTGIVVSLFRLSIEKLSD
                     LVRSIYEMSREQPIYLIGLAICCILAAFFVGYLVKNEPDIKGSGIPQVVGQLRGELSM
                     NWFSVLWKKFIGGVLSVGAGLFLGREGPSIQLGASIGQGAGQLFRSPSSEEKILISSG
                     ASSGLAAAFNAPIAGLLFVLEEIHHSFSPLVWLTSFASAITANFVSLYFFGLRPVLYL
                     GDLPSLPLKYYGSLVILGVLLGILGFIYQNVLLALPKFYNRLPLPAYFHGFVPFLLIL
                     PIGYLWPSTLGGGNQIVLAFGHASLPIIMIIGLFVLRFVFSMISYGGGLPGGIFLPIL
                     TLGALIGSFYGNIMVDFGMDPIYIKDFVVIAMAGYFTAIGKAPLTAIILVTEMVGSLN
                     HLMPLGLAALVAYIVNDLLGGNPIYESLLERLLGNTQTASLKGARTTFDFPVTAESSL
                     DGLMVRDFNWPKNMLLISIRRGNQEILTHGDTIMNVGDILVILTDEANLPRIKQEIEA
                     KSSITNLKQSF"
BASE COUNT        11760 a         9159 c         7551 g        13836 t
ORIGIN      
        1 aaaaacaaag tctttatttc tattatttac ctgtaaccgc aaagtagttg ccatcgggat
       61 cagcaaagtt aaagacatat tcttctccaa gctgtaccat atcacctaat gtgactgatt
      121 gcgtctgcat ttttttatat agtccaaaga tatctttact gtaaaacatc aaagatgggg
      181 cactagtagc tgtgccaggt gaatgggact caacaaatgc tcgatcatat aacagaaatg
      241 aggtttgact gtcctcaact cctacttcaa ttataagcgt cccatccatt tcttgacgat
      301 ctttttccgc aaagccaact gctctccaaa acgttgcatt tttttctaca tcgtccacat
      361 aaagcatgat ttttatttca ttcgtaaaca tctgtttcct cctaaacgat ctgttctaac
      421 attctcaact ttgtcagttt accataggaa aatgggaaaa tctacgaaag ctctcaacag
      481 aatcgtccta cttaaatacg cttttcttta ataataaata agttggttgt ttttgttatt
      541 tgcgctttca cttttcggaa taaataatgt gtatttatat ggaataaata aaaaaagagg
      601 tcgtgactaa aaacaagtca caacctctgg taaacggtgt tctcctgaca actcctcggt
      661 cacaagacac aatattcaac aaacatgaga agctattttt tgaaattgct ctttgtgact
      721 cagagtgaaa cggcaggctc acgacctctt tcttaaacgg tgttcaaaag cttgcatctg
      781 cggtaataag ctcaaccaaa cgtaaaatat gaggaactat ttttgtttgg ctgttcttat
      841 tacttgatgc agggcagctt tttcacaacc tcttattcac ggtgtttcag aagtagcttc
      901 tcggaaataa gccgaaattt cacaaaaatt tgagaaacta tttttaggaa acttcttctt
      961 atttcttaaa gctgaccact tctatcacaa cctctttttg actatgcatt cacatcgatc
     1021 actttagaat catcattgat gacatcgcga tctaaatctt tgatgcgtgc acttgtcacg
     1081 ataccagcta ccatgctacc gctgacgttt actgctgtac gtgccatatc gattaatggt
     1141 tcaacagaga taactaaccc aacgattgct actggcaagt tcattgcccc taaaacgatc
     1201 agtgaagcaa atgttgcgcc cccaccgact ccagctacac caaaagaact gattgttaca
     1261 attgccacaa gcatcaaaat aaattccaaa ctaaagacat tcactccagc tgctggtgcg
     1321 acgatcgttg ccaacatagc tggataaacg ccagcacagc cgttttgtcc aatagacaaa
     1381 ccaaaacttg ctgagaaatt agctgttgca tcatctactc ctaaagcttt tgtctgagtc
     1441 tcgatattca atggcaaagc tccagcactt gaacgtgaag taaacgcaaa gctcaatacc
     1501 ggaaaggctt ttttgaaata gttgattgga ttgacttttg caccaatcaa aatcagtgag
     1561 tggacaatca aaacagcaag caatgctacg taagaagcaa cgacaaattt acctaaattg
     1621 acgatagctg caaaatcact tgttgccaaa acgtttgtca tcaaagcaaa tactccataa
     1681 ggtgtcaaac gcaaaacaag cgtcacgatc cgcataatga ttttatacag actgtcgact
     1741 aaatctgaaa agaatgctgc ttcttttggc gcttttcttt tcacgcctag ataagcgatt
     1801 ccgacaaatg ccgcgaaaat aacgactcca atcgtacttg ttgcacgact acctgctaaa
     1861 tcagcaaaaa cgtttttagg gataaaggat aaaatctgct gtggaatcga taagttttca
     1921 actgtttcct gacgtgttgc cagttcagag attcgtgctg tttctgcagc tccttgtgtg
     1981 aatttagctc cttggagtcc gaacagcatt gttgaaccaa ttccgatcaa tgctgcaata
     2041 gctgttgttc caagtaaaga agtcaataca gtcgcactaa ttttccctag cttttcagaa
     2101 actttcattt ttgtgaatgc accaatgatc gaaataaaca ctaaaggcat aactagcatt
     2161 tgcaagaatg atacatatcc ttgacctaca atcccgatcc attccattga ttgagtaacg
     2221 actttgtcgt ctacaccaaa gatcaattga agcagaccgc caaagacgat accaactcct
     2281 aatgctgtaa agacgcgtgt tgaaaatttt gtatggcgct tttgcatacg atagaacaca
     2341 tataataatg ccgcaaaaac tagaaccact aaaactgtga tgagtgttgt catttttctc
     2401 ctcctcatat tattaatgac aagtccatcg aaggaagtaa aggttcccga gaatgattct
     2461 tcaaccatcc tcctgaaaaa atttttttca gtgactttta tattttagac gatttttatc
     2521 gaaatgacat tctttttgct tacaattagt aataaaaaaa catacctgtg atagctttaa
     2581 tctatcgcag gtatgttttt actgtctatt cttgtttttc tgattgaaaa ttcaatttta
     2641 ccccaggctg atctaaggcg atctctgtca cctcataaga cattcggcgt acgatatcga
     2701 ataacggtgc tactagctcg tccacttctt cttgtgtgac atcattttga ccttcaattt
     2761 tccgattgag gatatgattg atctgactca cacttccaga taaaacatat gtatcaaaca
     2821 ctaaacggaa ctctaagcgt gctcctacga tgctatgttc tttcggatag ttttcgatcg
     2881 tttcttttaa aggcgagaag cctactttca aatctgtttc tacttcttgg ttcggcaatc
     2941 tcatatcata atgaaatgct tctacaactt ctttttgtct tctgatttcc atataatttt
     3001 atcactcctt tatgaaaatt ataacatatc tcctttgaaa ggggatacta ctttttaatg
     3061 atgctctgca aggtaaggat ttcattcaga tttcctacca cataatctgc cgggatctca
     3121 cccagaaaat gatcgatgtc gtaaagacaa gtagcgactc ctgcattttt ccctgcttcg
     3181 atatctaaac gacgatcgcc gatcatcatc gtgtctgttc tttctaaatg aaaagtatcg
     3241 atcaaataat ttaaagatgc tggatcaggt ttacgaggaa agtcctgatc gatccctact
     3301 acttcctcaa tcagatgtgc caatcgatgt tcttttaaca ggccccatgt tgattctgtc
     3361 aaacggtggg tcaggatgaa atgacgaccg ccgttgtctt ttagcatttc cagtacttgt
     3421 ttcgtttctg gaaatggacg ggaaacttcc gtactttctt tttcatatcg gtgaaataat
     3481 tcattaaact ctctggcatt caagtttgat tcattgatca aataactagt agaatacttt
     3541 ttcattttga agtagatttc ttttttgtcc atactgatac caaaatcttt tagtgcttgc
     3601 catgcaccat ctaccattgc gggatacgta tcaaacaatg taccatcaaa gtcccatata
     3661 taatttttca tgttcctttt gttccattcc tttgcttctt ttttctatct ctcactttta
     3721 gataaaggtg ttctttaaag tatttttttg tccagaattg tcaaatcatc tgctaatgta
     3781 tactggattg gttgtgcatt tgggatatcg atcgtatcca tttgatcttc aggaacatct
     3841 tctaaatatt ttgtcagtgc tcggatgcta ttaccatgac ccacaactag taaatcttgc
     3901 cgatctttta gttttggtgc tagatgatct tgccataagg gaatgatccg attcactgtc
     3961 atttccagac tttctccgta tgggatcaaa tgcggatcca agtgatcata tctgcggtca
     4021 aatctatttt ctgcggttaa cggcggaact tccgtatatc ctctgcgcca tgtttttact
     4081 tgatcttttc cgtatatttc tttcatctta tctttgtttt tacccacaag atccccataa
     4141 tgccgttcat ttagacgcca tgtttttatt ataggaagcc ataactgacc catttcttct
     4201 agtgcgactt gtccggtaag aatcgcacgt ttcaaaacag aggtataaac ggcatcgaat
     4261 tgaagtccgg cttcaagcat tttttgaccg gcaactgctg cttgttcttt tcctttttct
     4321 gttaaggcga catctagcca tcctgtccag taattttcaa aatttgcttc gctttcgcca
     4381 tgacgtaata atactaattt cattcttttc tcccttaaac attcgtttcg aattttatac
     4441 cacatgtttt gcatgtcaca cgtattcgtc cttttccttt aggtgcacgc tgcttttgat
     4501 gacaattcgg gcactcaaaa aaagtataac tttttcgatc cattttgact tgctttttgt
     4561 tttttatctg atgatatttt tctttgactc tatcaagata tttcaaataa cgttgattct
     4621 catttagtct ggggtagatt ttttttgata ggaaacgaaa tatcatccat ccgaaaaaga
     4681 cgatgaacaa caattgtccg attctatagg gcaaccaacg acttagcaaa ctaaagacaa
     4741 gcgcagcgat caatagaccg cgattcaact gatcaaattt cgcatatctt ccctgcataa
     4801 gtttgtgata gttctgctga aatcgtatta gcctttctaa ccatgtttgc atcatattat
     4861 ctcctccatc atctaatatt tattatgaca aaaaaatcca aaaagaaaaa gccttaattg
     4921 gccttttcca ttgcaacttg gtgaaggaca ttccgatttc tggtaaagtc aatcacaatc
     4981 actttctttt tatcttctct gttgactact cgaaatgtgt ccgtcaatgg aagaaacagc
     5041 ttcttagatg gtagctgttg catacgtata aaacgatgga tcatcgtaat caattgagga
     5101 aattgaatag acgtgtgaag cagacctgga tattttttca acagctgtgt cgttttgatc
     5161 agattccgtt ttttactgat cactttttaa aagcttttta gaatcttttg ctgacgtcta
     5221 aaaatagaaa aagaattttc gtcatctatt tgataacgca tttgtttttg cagttctgct
     5281 gcagtcagat ggatcttccc atcgtttgta tcgatcatta aaccttctgg aaacagttca
     5341 accactgctc gatcccaaga ttcaagagaa agctcgatat aatcttttac tggtaattcc
     5401 aattctacct taaaaaagtg caaaacagcc gacagccctt ctgcttgata gatttctcct
     5461 aatgttagcc cctctagatg gaactctggt gaaaaatgca gcaatgtttt attttcctgc
     5521 aattgaacat atagaaatgt agatcgctca atcagagtat cttttaaaac aactaaaaaa
     5581 ttcatttttc tccccctttt ttcatcattt ttaaaatagc atattttgaa aagaaagtct
     5641 gatgcttaga gtagaatttc ataaaaattt actatttcat aagtattcac gagaaaaata
     5701 caaacaaaaa agcggaaata acgctcatcc gccttcttgt ttgtgtttat ttcctcttca
     5761 aacgcttgtc tatgattcag acttttctct atcgttattt tcatctaaaa gttcttgcat
     5821 tccgataatt tctcgatatt gatgaatctt agtgatacca atgactttgt ctacatcaat
     5881 actaaaacaa ataccattac ctggaatatc gatgttgatg ccttgaccaa tcgcatccat
     5941 tactttattc gtcaaactat cgggtactaa tgtcaacaca atatcttttt ctggcgaaat
     6001 gtccaaacct aaaaatttcc ctgaatcatg tacaccagaa cctcttccat gtaagatcgt
     6061 tccgcctgct gcacctgctt cttttgaaaa gtcgataaca tcttcgccca ttcctccgtc
     6121 aacgatcgtc acaatcatgt gaagattcaa tgctacaaga tctttcattt gctttccccc
     6181 aatttttgca atctttcttt ttcgattctg tctttttcat cttttcgttt ataaatatat
     6241 cctagtacta aagtggataa tattggtgtc aatgcaatca ttgcaaccac accaaacccg
     6301 tcaatgatcg gatctcttcc ttcaatttgt gcagcgattg ccacgctcat tgataaaata
     6361 aatgtcgaac acatcgggcc cgttgctact ccaccgttat caaaagccat tgctaaaaag
     6421 atcttgtcca cttttcgtcc taaaataaat gctagcccgt atcctgggat caagaaataa
     6481 taaagagaga atccgacgag caaacgccac atagacaatc ctactgctgc gccgatccca
     6541 attgaaatta ccatcagcat gattttcgat cggattctcc cctcgctcaa ttcttcaacc
     6601 tgtttgatca ttacatgaat cgccggctca gcaaacccta ctaagaaccc cattaaaaag
     6661 ccaaggggaa ccagtatata attgtaaggc aatcccgcaa tagcactgcc taaatgctgt
     6721 cctaccggta cataagccat attgactccg tgcaggaaaa ggatcaaccc aatagtcgtt
     6781 atcaagaaac ctttcataat gtcaaagaaa cgctttttgc gcatacgaaa actaatgata
     6841 ttcattaaaa caaataggat tacgataggt gccactgcca aaatgacttc catggtaacg
     6901 atttcgattc catctatcac ttgctgccag aaactcattg gaagatcacc cccaaaatca
     6961 tcacggcaag aatcggccct aacgaagcaa taccgaccat tccaaaactg tcattttcat
     7021 ttttcttttg tttgatcata ctagtcatcc ctccggcaag ggccaagata aatggaacag
     7081 ttactggacc agtagtcact ccccccgaat caaaagcaat cggcataaat tcggaactgg
     7141 tgaaaaatga ggcgatcaaa acgcctatgt agcctatagc catcaattga taataggata
     7201 gcttgaatac gacccgaagc agcgcaaagg ctagaaatac tccagtgccg acgctgacga
     7261 tcccaatcag caacactctg ccaatctctc cgtcagatat atcatatact tgttgtccca
     7321 aaacttgcac ggaaggttca gcaatcgtga tcacgatccc gatagcaaat cccaaactga
     7381 ccaaaacggt caaacttttc tttttgatca tatatttccc tactagatct ccgacttcca
     7441 tcatagaata atctgctcca aacaaaaaga gcgtcattcc gatcatcatg attgccgcac
     7501 caaccagaaa tgaagcgagg tcttctcctt ctaacggtgc aaaaacaaac gttaaaatga
     7561 caatcaggac agtcatcggc aatatagcag caatcacttc tttaaaattt tttagcatgt
     7621 atcctcctcc tttactcttt aagtttacct taaaatgaaa gagttttcga gcacaaactt
     7681 aaaacgttat catttaattt ttctcaacat aaaataacac acgtcccaaa agtatctttt
     7741 tacttggaaa aatgactttg aaggaacgcg cttattgtgt ttttttattt tacagagccg
     7801 atcattcctt gaacgaattg cttttgcaaa acaaaaaata cgatggcagt tggtaaagta
     7861 gcgatgacta atccagccat gatcattcca tagtctggtg tataggaagc acccatagca
     7921 gataaaacaa gcggaaccgt ccgtttatca ggagattgca aagctactaa gggccataaa
     7981 taattgttcc agctactcat gaatgtgatg attgcagccg cggcataggt atttttagcc
     8041 gtcggcatat acactctaaa aaaaatactt agttctttta gaccgtctaa tcgagcggct
     8101 tctactagat cttttggaaa agatttaaca ttttgtcgaa agaagaagat caaaaaagca
     8161 gtgctaacag atggcaggat gacaaccaag aaactgttga ttcccaaaac cgttccgttc
     8221 aattgtgaaa acattcgata taaagggatc atcaatgccg caaaaggaac catcatcgat
     8281 agcagtagaa tattgaaaat taggtctttt cgtttacttt gataaatctc aaatccatat
     8341 cctgccattg acgaaatcag caatgcaaac acagtggtca ccaaagcgat catcgctgaa
     8401 ttccaaaggg aacgagtaaa attcagctca ttggaaaaca aattttgaaa attgatgatc
     8461 aagttactgc caatctttat ttttcccgat gtgatatcca cgggtgtatt cgtcattccc
     8521 aaaaccatcc agacaaaagg gaaaatggaa ataaatgata ggatgcttaa tgctgtatac
     8581 tttaatactg acccaattgt cgaacgaagt tctaatgctt gttttttgac gttggggcgt
     8641 tcgattgttt ctttttctac catatttttc atcgactttc tcctcctact ttcgtttgga
     8701 ttatcgacaa tatcacaata aaggaaacaa taacaaagga aactgctgcc gcatatccaa
     8761 aattaggcgt gaatttataa ctcaaattat agatgtattg agatagggtg gtcgttgcat
     8821 ttgctggtcc cccgccagta atattttgta cttcatcaaa aagctgcaat gtcccgatcg
     8881 tcgaagtaat ggaagtaaac aaaatgattg gttttaaatt tgggatcgtc actttgataa
     8941 actgctgcca tttagaagca ccgtcaatag atgctgcttc ataaatctcc gaatcaatat
     9001 tttgcatgcc tgaaaggaaa aaaatcatat tgtatccagt ccaacgccaa gtgatcgaaa
     9061 gaatgatcag aactctcgcc caaattggat gagtcaacca gccaatcggt gtgtcaatca
     9121 taccaatgcc caacaacaag ttgtttacaa ggccagattg agaaaataga cttttcatga
     9181 tcagagaata actgaccatc gaagtgatac atggaagaaa gatagcggtt cgaaacaacc
     9241 ctttatattt caacttttta tcatttaaaa ggttggaaat aaaaagtgct agaaacaaca
     9301 tgatcggtac ttgtacaagt aaatacagga atgtattaaa aaaagctttt ttaaaagttg
     9361 catctgtcaa catccgctga taattaccta acccgttaaa tgtcatattg acagggggac
     9421 cactttgaaa agacgtgatc aaagccaaaa ccatcggaat aaaaaccatg attgatatca
     9481 aaatgactgg caagattaaa aaagcatgcc cgtttttgaa taaatctttc tgcttcattc
     9541 ttttccctcc aattctatca ttgattatct acatgaaaag acaagaaaga caatatctgt
     9601 aaggcagacg tgatcttttt tgtcttttcg tttgtctgat gaaaaagcga agaaattcac
     9661 ttttttacca ccgatcaatt agccaattgt gcttctactt gtttttgtgt atctgctagt
     9721 accttgtctg tctcttctcc attgatgatt cgatgaagag cttcagctac gactgcttca
     9781 attgcatagg tctcatgtcc gtaattcact tctggtattt cagatgtcca tgttgaaaaa
     9841 tcgtcaaaga tcttttgacc actgtaaaat tcagaagctt cttgataagc ttcttgttca
     9901 ttcgcgctaa gcatcgtaga tactagtccg atttctttcg caagagtgcc catcagttct
     9961 tcattcgaag caaacgttgc ttctaggaaa tctttcgctg aatcttctcc agctactcct
    10021 ttgatcacat accagccagc gccgccaagg ttagaagctt gcgctttttg cagattttct
    10081 ggaagtgcag gtattggtgc aatcttccat tttccagatt ggttttctgc tccttggatc
    10141 gttgaagaat accaagcgcc agttgggcta gaagctactg ctcctgattg tatcgcagtt
    10201 actccagcat tccagtcaga ggtttgttcg actagatctt ctttcaaaag agtggcaaac
    10261 aattcaagac catactttaa agatgcattg tcttggatcg tgactgtctc cccatcttca
    10321 gatgtatacc attctcctgc ctgttgcata atcatcctta ctcgaccaag gtcagaagga
    10381 ttgacttcag cgattttctt tcccgtcttt tctttgacat ctcgcgctac ttgaatatac
    10441 tcgtcccact tcagattctc catatcctct tctgtataac ctgcttctgc catcagatcc
    10501 gtacgataga agtttgctgt tacgcccgaa tcgaaaggaa caccgtatat tttatctcct
    10561 actttgttta ccgcaaattt atacggtgca aaatgatctt cctttacaat agcagacaaa
    10621 ttagcgaatg catctggata agaagtcaaa tagccttgta tcctataatc ttcaatcaag
    10681 acgatattgg gcaatccttc tgtattcccg ctcgctaaag cggtgttcag tttctgaacg
    10741 atatcatcct gagacatcgt aacaacttct atctctgttt cttcgttctc ataaactttt
    10801 tttgcttcat tcactgcttt gatattgaat gtctcatccc acgcccagac agtgactttt
    10861 tcttctttgt ctgctgtact actagcactt ccgcatcctg ttaagaaacc tgatgctgcc
    10921 gctaaacaaa cgactccagc aattaacttt ctgatgttca tttttatccg ctccttttcc
    10981 atccattagt tgtttacgtt tgctacattc atcataccaa agtttgaaaa cggtttcttt
    11041 attattcaga tacttcaaaa atttctccta aaataataaa aaaatacaaa tcaactatga
    11101 caaaaggaat aatcttagca tctagaccaa agatcgaaat ggtgaggttt ctttaaaata
    11161 aaaatatcct tgcattttct cctagaaata agtattttta aattacaaga ctattcttaa
    11221 ggcgggtaaa aaaatgccaa tacgcgtaat tcttatcgat gatgaacaga cgattttaga
    11281 tggaatgaaa cagttgatca attggtctga gcacgggttt caattaatag ggactttttc
    11341 cagtccgctg aaagcgcttg atttttcttt ggtacatgca atcgatatcg tggtcacaga
    11401 tgtaatgatg cctgaattaa atggaatcga attatcgcgg ctattaaaac agcaacaacc
    11461 tgaaacacag atccttatcc tctctagcta tgatgaattt gatatggtta aagattcttt
    11521 taaagaaggc gtcgctgatt atcttttaaa gcctcgattg agtcctgatt tttttctaaa
    11581 ttccttaact gccgtttcac aaaaaatcaa aaaaaagccc aacaaaagcc caatcaccaa
    11641 tcgttatgag cagatctgcg agaatctttc acagcagatt gctggacaaa ctcgtccatt
    11701 gcttgaccct cttctttttg aacacacctt gtttttctgt tatataccga aaaacggcca
    11761 ttcagttcaa aacaaggctc taaacaaaaa cagtcgatca cccattcatt gatggatagc
    11821 gacgattcgt ttactattta tcctgtttct accttttcgg aagaatccgg ctatgtaatc
    11881 aatactgatt ccaaagatac acttaggaag tttgttcaaa agtttcgtca agaagttttt
    11941 ccaggtgatt tttttgttgt ttctgattct tttgcaatcc aagatatcaa tgaaatattc
    12001 caagagatca gaaattgcac caaaggacaa cgtttctatc ataagggaaa gaaccttgct
    12061 tatcagcatg aacttcttcc gttattaacc aaccacgagc agcaagcaag tagttattta
    12121 acaaaaatcg ttcataaaga ctacgcttta gctgtcaaag aacttgagaa tttcttcacg
    12181 acgatattgg aacagcctat tgatccagct tatttgaaac atgaggcaat caatcgtttc
    12241 tatgcattac tcaacgcttt ggctgacgag catgttggga atgaagaact ttctttgctc
    12301 aagatcgccc ttccttcttt attagccgat gctgagtatt tcgaagattt ttctattctt
    12361 gtcaaagaaa cacttgagaa actcacccac ttttctgcaa atgcaaaaaa agacaatttc
    12421 gatatcttga ctttgatcta cgagttcgtc caggaaaatt atgagaaaga aatcaattta
    12481 caacttttat ccgaaaaata tcatttttca tatagctatc tctcagccat ctttactgaa
    12541 aaatttggta tcaacttttc aaaatatcta aaaaaagtcc gtatcagtaa agccaagctc
    12601 tttttgacgg aaacacggct tactttgacg gaaatctgtg agaaagtcgg ctataccgaa
    12661 ctgggttatt tctccagagt ttttaaagaa gagacaggaa tgacaccttc tcaataccgt
    12721 aaaggaactt ttgtaaaatg agaaaaaaaa tcaaagagca tgaactcttt gccaaacttc
    12781 tgttcatttt gttcatcggt ctttttctgc aagccatcgt catttctttg tttatttatc
    12841 atcgatcaag ggatgcctat atccagctgt tcaatcaatc gaatgatgtg gtactaaaaa
    12901 agattcaatc tgaatttgaa agtttgaatg atacaatcga gaatacatta gccgcttttg
    12961 attctaatcc agctgtcaaa agctattttt ccaatgatcc agcccaacat atggaacagc
    13021 ttcagcaact aagaacaatc caaaaaatga atgactctct ttcaaaaatc catccaatga
    13081 tcgattacga tgtattgatc tttggagaaa atggaagaac ttttgtcgga aacgacatgc
    13141 tcactgccgt atctgccgat tctttttttc aatctgcgat tgctcagaga gtgaatgaac
    13201 gtgctgctga tacacaaatg ctttttgcac accacggatt gactcttcgc gataagaaag
    13261 cacccagcgt cttctttgtc aaaaaactga aaaatacatt gaatcacgtt tacggatatg
    13321 ctgttttatc gatctcatcc aagcaactag cgaatctttt tcaatctgta gtaaatcctg
    13381 agatatcgaa gatctccttc atgaacgaag aacagacgat catcgcatca aatgaagaaa
    13441 atacaattgg gagccgatca atgattttca aaaaactaac agtaggtgaa acaacgattt
    13501 caaatggaca gcagttgacc cgtcttcctc tgtaccgcca ggattgtaca ttactcagtc
    13561 aagtcgatct tcattcttta tctaaccaaa tgggcgtgat ttttccgatt attttgtata
    13621 atatcgtgac acttgctttt gctggctcat tggtatttat gtatttggat cgacacacaa
    13681 aatcgatcta ccgcttgatt gattcgctaa aacggctaga ggaagatggc ttaaaagcta
    13741 ctgttcctgt acaaggaagc catgaagtcc aattgctagg gaatacgatc aatcaattgc
    13801 taagtaatgc tcagcatcat tatgaacaga cgatccaaga cgaaaagaag aaacgttcgc
    13861 ttgaaatcca aactatgcaa gcacagatac agccccattt tatttataat acgctgacta
    13921 gcttgaaatt tttgatttgg cagaaaaaaa cagatgaagc agttcaagga atcgacagtt
    13981 tcattacttt actaagaagt acgattggga aaaaagaaga agtgattcca gtcaaggaag
    14041 aaatcaaaag cgtacaaagt tacatcgatc ttttgagtat gcgatatggc gaaagaatct
    14101 cggctaaaat aatgattcct gatgaactgc agtcattatc tatgccgaat atgatccttc
    14161 aaccaattat cgaaaacgcc tatcttcatg cttttcacaa taaaacgcaa ggattcatca
    14221 cggtgtacgg caaaacaaaa aatcagcttc ttttattcga agtgattgat aacggcgatg
    14281 gcttcgatac tgaaaatacc aaacaaaaaa atgatcattt ttcaggaatc ggcatcagcc
    14341 atgtagatga gcggatacgc ctaatgtatg gcgatgcata tggcttaacg atccaatcag
    14401 tgattgggac aggaacgact gtaacgattt gtctaccgct tcttcctaaa aatcaatcag
    14461 aatatcaaaa ataaagaata gccaagcgct gattttttta ttttaagtta aataaatcaa
    14521 tcagtattct tgactttcat ctacgcgtct cttctactgt cagcactgga taacagccca
    14581 atatttgact ttctcctccg agcatcttga tttcttggag cgcattctct actaatgtca
    14641 ttggacggtc caacaacaaa tcgatcacga aaaaatattc tcccaagcta gttttcaatg
    14701 gtcgggattc aatcttactt aagttgattt cccgccagcc aaaagctgcc agcattttat
    14761 gaagcatccc tggccgatta gcaggtagtg tcaagatgac actcattttt actggagctg
    14821 actgctggct ggtcatcttt cggtcaccga cgatccaaaa acgtgtctgg ttcaactcat
    14881 tatcttggat attctcagct aagatctcca atccaacatg ctgtgctgtt tctaatgaag
    14941 caatcgctgc tgcgtcttct ttcggatgtt ctgctacata cattgctgca gcagttgttg
    15001 attctgttgc tactaaagga acattaggat aatgcgtttc taaaaactgt tgtgattgtg
    15061 ctagtgcttg tggatgtgaa aggatttttg taatctttgt tgctggattg cctaaaagct
    15121 gctgcttgat aggaagaacg atttcacttt taacttcgac ttctggatgt ttggaaagaa
    15181 gatcgattgt gtgatgaaca gctccttcca atgaattctc tacaggaacg acagccagat
    15241 cgacttgttt gcgaaacaaa gcgcgcaaac aaacagggat ggaagcatac gcagtcaatt
    15301 gttctgtagg aaatagctga caagccgcct gataagtgaa tgaactttct ggccctagat
    15361 agctgacgtt catatgcttt tgatcctttc tataatggta tcgatgatct tttctggtgt
    15421 ttgattggtc gtgttgattc gatgtgtcgc actttcttca taccaagaaa gtcgttgtgc
    15481 caataatgct tttatttctt ctcttgtttt tccaagagct aaaggtcgaa tagacgtttc
    15541 atcttgttgg atacgatcaa ctagacagtc cgcttctgcc tctaagtaaa gaacaatcgg
    15601 ctgtgttttt aaaaaacgcc gattttctgc actttggaca atccctccac cagtcgcgat
    15661 aattttgtct tcatttgaca gctttcttaa aatatctgac tccacttttc gaaagctttt
    15721 ttcaccgtaa tagtgaaaat attcggcaat cgacaattgg atatgttcct caatctttgt
    15781 atctaaatct acatactctt tttgtaaaca ttgagctaac cctttaccga ttgttgtttt
    15841 tccagcgccc atgaaaccaa tcagcaaaat gctagccatg agcttctcct cctgacacaa
    15901 gttctgctaa atcgtcaaaa aatgccggat aagagattga aacagcttca gctccttcta
    15961 gttcgcaagg tccatcagct atcaaagcag ctacttgcag catcataccg attcgatgat
    16021 cgcctctgct ggacactttt gcgccatgca gaggtgtcgg cccatggatg atcagaccgt
    16081 ctgctgtcgc ttttatcttt gctcccattt tctgtaattc ttctgccacc gcatcaattc
    16141 tgttggtttc ttttactttt aattcttctg cgtctttgat gatcgtgatt ccttctgctt
    16201 gagtagccac taaagctaga atgggcaatt catcaatcag acgcggaatg atttctccac
    16261 caatcgttgc tttcttcaaa tgactcgtct tgacacttaa atcagccgat tggttctgtt
    16321 cattgtgatt cgtctgggta atcgctgcgc ccatctcctc caacacatct aagataccag
    16381 ttcttgttgg attgaccccg acatttttta acaacagttg gctttccgga acaagaagtc
    16441 ctgctgctag aaagaaagca gctgatgaaa tatcacctgg aacagttatc tgttgaccag
    16501 ttaatttttg cggtccggtc actatgatcg ttttatcttc cactgtgatc cttccgccaa
    16561 attgacgaat catttcttcc gtatggttac gggaacgttc tttttcaacg attacggatg
    16621 tgccttctgc ttgtaatgcc gcaaacagca aagcagattt gacttgcgca ctggctacag
    16681 gcatattgta tcggataggt gataaagagc gggttcctgt cacagtgatt ggtagatact
    16741 ggtcattttc ttctccttgc aagtcagcgc ccatctcgcg taaaggttcc atcactcgcc
    16801 ccattggacg tttagacaac gaagcatccc cgaacagagt agtcgtaaaa ggctgtccag
    16861 ccaaaatacc catcaataaa cgtatggtcg taccggagtt tcccatgtca attgattcgg
    16921 ttggttggac aaatgagtgg ctaccgcgac catgaatctt gatcacctct tcctcttctt
    16981 cgatctcgac acctaattgt tggaaggcat gtaaagtact cagacaatct tctgcgcgca
    17041 aaaaattttg tatagtcgtc gttccttcag caattgctcc aaacatgatg cagcgatggg
    17101 aaattgattt atctgctggt atcctaacag tccctcttaa tccatgtatt tgttgtaata
    17161 attgcattta tccagcctcc tatttgatcc agcaatgata actggtatta gacataatga
    17221 ttctttttgc ttgtaacaaa tcctgttggt ttttaaaact gatttgcagt attcctaaaa
    17281 tatcttccct ggtctcttgg atcttcaaat taatcaaaga aactcccgct tttccgatca
    17341 gtccagttac ttctgcaata acgccaggtt catctggcac atcgataaat aaatcaaaaa
    17401 aggcaggaat cgcgccttgc ttatggacag gcaactggtc tcgactttct tttgcccgat
    17461 tgaaaaaaga aaagatttcc gattggttct cagtcatgat ccattctgct atttgtgtca
    17521 tttcttgttg ccaatctgcc aatcgttcca ataatatctg cttattgctc aacaaaatat
    17581 ctgtccacat gacaggatct gaggaagcga tcctagtgat atctcgaaag cctcctgctg
    17641 ccagttgttt ggctcgcgga tactcttgat tgaattgttc tgcctgattg actaagccag
    17701 ctgccagaat atgtggaaaa tgacttagca ttcctgttat acggtcatgt tctcttgctg
    17761 taagagttac atattttgct ttggttccgc aaaatagttc ttgcagtttt tcaacatctt
    17821 ttttcgtctt ttccaaaggt gtaaagatgt aataggcatt ttcaaatagt ttagcatctg
    17881 ctgcctgtat acctgattta tgagaaccag ccattggatg tccaccgaca aaccgaagat
    17941 ttttctgctc agcggatgtc acgacttgct gcttcgtact gctgacatcc gtaatgatga
    18001 cgtgatcaga caagttgatt ctttcaagga catcaagata agctaaggtt gtacggacgg
    18061 gaacggctaa taagataacg tctgcttgtt ctgcacctgt ttcaaaatca cttgcaacgt
    18121 aatcaacgat ctgctgttct actgcttgct cacgggtttt tgactgacta tcccaaccaa
    18181 ctactatcag ttctggattg gtctgacgaa tacaaagtgc catagaagca ccaatcagtc
    18241 caagccccac gataaaaaca tgttgtgcca tcttatttgc ccccttttta gtaatgtttc
    18301 aagtagtcac ggtactcctt cactgcagct ttcaactcaa caagcgaatc acttgggaat
    18361 tttgacaata gctctgtcgc taccacagtg gctacaacat tttccgcaac gacgctagct
    18421 gcaggaactg ctgtactatc cgaacgttct acacttgctt tgtaaggttc ttttgtatcg
    18481 atatcaacac tttgaagtgg cttgtacaat gtaggaatgg gtttcatgac cccgcgaatg
    18541 acaagtggtt cgccattggt cattccgcct tcgaagccgc ctagattatt ggtacgtcgg
    18601 aaatagcctc tttcttcttc ccataggatc tcatccatca cttctgagcc tggtaatgaa
    18661 ccagaagtga atccgacccc aaattctacg cctttaaagg cattgatact aaccacagct
    18721 tgtgcgattt tggcatctag cttcgtgtcc cattgtacgt agcttcctaa tccagctgga
    18781 acgcctccaa cgagcacttc tacaattcct ccgatcgtat ctccattttt ctttgtctga
    18841 tcgatcaaat cttttattct ttgctcaact gctggatcaa caactcgtac ttctgacgct
    18901 tcagaaattt ctttgatttc ttgaatcgag atatttccag gtatttctgc ttggattcca
    18961 ccaagacaaa tcacgtgtcc tgctacgatg atgtcaagtt cttccagaat ttttttggca
    19021 attgcgccga ttgctacacg catggtcgtc tctcttgcag aggaccgttc aagcacattc
    19081 cgaagatctc gatgatggta tttcataccg cctaccaaat ccgcgtgtcc tggacgcgga
    19141 cgtgcaactc gccgcagtga ttggtctttt tcaggcactt ctgctacaga catgacagtt
    19201 gtccaatttt tccaatcttt attttctacc actaaagtga caggtgaacc aattgttttg
    19261 ccgtgacgga tgccagacgt gatccgaaca cgatcttttt cgatcttcat ccttcctcct
    19321 ctgccgtaac cagcttgtct gcgagcgagt tcgtgattga tttcttcttc tgacagaggt
    19381 aatcctgctg gtagtccttc aataatggct gttaattctg gtccatggga ttctcccgca
    19441 gtcatataac gcatcttaca gtcctcctaa gtaatctttg aatgtctctg tgggaacagg
    19501 aacgattttt gcttgcccaa tcttttctag caagatgata ttcaattggc ttcctcttgc
    19561 tttcttatca tgggttatcg cgtggaataa ttcatctgga tgacttagat cgtacgtaat
    19621 cggcagatgg aatttttgaa gtatcctttc taaagcagct gtcgatccag ttggagacaa
    19681 gccgattttt tctgcatgag aagtgatggc taccattcca atagctactc cttctccatg
    19741 actgactacc ccatatcctg ctgtattttc aattgcatgg ccaattgtat gaccaaaatt
    19801 taaaataagt cgatttcctt ggtcaaagac atcttcttcc actacttttc gtttgatttc
    19861 caacgtagca gtaatgattg gaacagcatg ttccagaaga tctttttcgt ctttcagctc
    19921 gttcagctgt ttccaaagcg ttgcatctgc tatagctgct gatttgatga tttcagcgat
    19981 tccttctcgt aaacgacgta ccggcaaagt ttttagaacc tcaggatcaa tcaatacacc
    20041 agctggctgg ctaaatgttc cgacaaggtt tttcgctttg tttgtattga ctgctgtctt
    20101 cccgccaata ctagaatcta cttgtgcaag tagcgtagtc ggaatttgaa cgaaatggat
    20161 cccacgcatg aacgtcgagg ccacgaatgc tgctagatca cccaccattc ctccaccaag
    20221 tgcaagtatc ccatcgctgc gggtaaaatc attatctgct aaaaaatcgt ataactcagc
    20281 tgcttgttct aaagatttac tggtctcacc cgccggtacg attgaaagga ctggttcaaa
    20341 attagcttgt ctcaattgga acatgatttt ttctgcatat agtggagcaa cgtttgtatc
    20401 agtgatcaca gctacttttt gaggtctcca aatcgtttga agccatgatc cagcctgttc
    20461 tagtgcgcct ttttcaatat gaatatcgta tttttggtta tcaacatgta cagtaagcat
    20521 tcgtttcact tctttctttt aaaaagctgg aattaatcga gtgtctgaat cttttccatt
    20581 gcttctttca tgatcgcaac ttctttcatc atgcgtgagt aagtcttttc attcaacgat
    20641 tggggaccgt ctgaccaagc atttgcagga tcaggatgga tctctacgat catgccatct
    20701 gctccgcttg ccacacccgc acgagccatt ggtggtacaa gttcccaaat tcctgtacca
    20761 tgacttggat caacaatcac agggaaatga gttaattttt tcatcaatgg gacagcactt
    20821 aaatcaaacg tattacgtgt cgctgtttcg taagtccgaa tcccacgttc gataaaaatg
    20881 acaggagatt tgtcttcgac tgcaatgtat tctgcagcat taagccattc attgatcgta
    20941 ccggaaattc cacgtttcaa tccaacaggt ttacctgttt taccgacagc agatagcagt
    21001 ttaaaatttt gcatattacg tgcgccaatc tgtaggatat cgctgtactc agccaccata
    21061 tcgatatgcc cttcatccat cacttcagta atcactttca ttccaaattc atcagccgct
    21121 tgacggatgt atttcaatcc ttcttcttct aaaccttgga aagcatatgg agaagtacgt
    21181 ggtttgaagg caccacctcg cagaattttt gcgcccccgg ctttggccat tcgcgcacat
    21241 tctctgattt ggtctaatcc ttcgatagaa caaggaccag ccatcgtcac gaaactgccg
    21301 tcaccaattt ttactccgtc tacatccacg actgtattgc caggatggaa ttctcgagaa
    21361 gtcaatttgt atgtgtttaa aatacgcaca gcattttcta ctccttcata gcgtgtaaat
    21421 gctccttctt gtaaacttcg cgtatcacct tttagtccaa tcactactcg ttctgttcct
    21481 tgatcgattg agactttgaa tccttctttt tcgatatgat cgacgacttt ttttatttgt
    21541 tcttccgttg cttctttttt cataattact atcattgttt ttcccgcttt cttttgttta
    21601 cttatctatc ttggctgatt ttctctactt tttcaaggtg gttttacatt aattcctact
    21661 aaatgaccgt gtcctgttgt tctcattttc gctccttctt tcctacttat gacccagata
    21721 atcaacaaaa aaagatgtcc ctgtaggaaa ttgcctctac agtgaacatc ttcaacgagc
    21781 cttaaaaagc gctgcaaaaa tataaaatag ccactataga tgaatttctc tacgtggctg
    21841 taagtcgtgt ttaaaaatct ttagccatca tagatacaaa cctggtttgt ttgtacccac
    21901 gaagtcatga atacaaacct atctaaaata gctaaagtaa tacgtattca gttttgtaag
    21961 ttttctagat ttcataaaaa atcgctccaa actgatgtaa gaattgtacc tagtatagac
    22021 ataaaaaaat cgactgtcaa tcatttttat gaaacttttt ttaattttct gatagttaac
    22081 tttgtttttc agaaaaataa caattggttt tattgaagaa aatagtcatg aacaaaagta
    22141 tctgagaact tttttactct cttgttcatg acatatagaa taaagcagct ttgtcttgta
    22201 aactccgttt ttcaaataat aatctaaaga ttgctactga ataataaagc cgatttcatg
    22261 gtcctcttcg ctgctgattc ggtaaggtga ctcaacatcc gctccccagc tattgatacc
    22321 cccgactcct cttacttttg caaaaatcgt aagaaccgtt cgtctttctg gcggtagttc
    22381 ttctatatgt gttgcctgtt ccagttcttc tgctttgaat ggtaaagcgg aaaaagcaaa
    22441 tggcgtatcc tgctgttcaa atcgcaacga aaaatcttct tgatctttat ccgtattatc
    22501 caacgtttga tttcttgtta gttctaccca tttcgtttcc atatgcatgc cgcattcttg
    22561 gggaacaagg tatggggaaa cggggagtcc tgccacttta taaatacctt cgacaccacc
    22621 agccatccga tccggatatg tttcccctga taggccttca tactcaaaaa attttgcttt
    22681 cgttggcata atgaacctta aacccaatgc gggtaattcc ggtaatcctt tttgtccata
    22741 ataatgcata ttgacaagca ttttaccctc tccagcgatt tggtaggaaa ttgtcacttg
    22801 ggtttttggt actgtgttga tttccagtgt aaaaatgatt tcaaccgttt cagcgtattc
    22861 attacttgaa tattgattat ttactggagc aatcggcaaa tcgatctttt tattgtccac
    22921 cagtacttct atttctttga cttttggata caatccggct cctaaccaca taccggattt
    22981 aaatccaaat ccgctacctc tgtcattatc ggtcgttgct cgccaaaaaa ctggaagtgt
    23041 ttcccggtat agccattctt ttccgttttt attgagcgat tccagtccgc ctcttgtata
    23101 agaaaaaata taatgcgtat tccccgattt gacacctaat gtacagtcgc cgaagacgat
    23161 tgcaactttt tccgtatcca tatgactttt atttactgta tttttcataa taatatctta
    23221 cctcctgcat ggcgggtttt tcttgtccat ctgcaaaaac gatcccattc cctgagaatt
    23281 catagtcact tggtttatcg tcaaagtcac cgccatagcg catcacttct ctgcctgtga
    23341 ttggatcagt cacttggatc gcctgatctt taaaatccca tatatagcct ccttggtaca
    23401 tttcataacg atcaagcaac gtcatgtaag aatccattcc acctaacgaa ttccccatgt
    23461 catgcatata ttcacataag atgaacggtt tttccgcttt attttcaagg tagtcaatga
    23521 tctcttctgg tggcgcatac atgcagcttt ttacatctga aatcgaatct tcgaatgctg
    23581 gatttggaaa attcccttca taatggacaa gtcgatcggg gtctactttt ttgaagtaat
    23641 cgttcatttg tcgaatgttt tcttccgcat aagattcatt tccaagagac caaaaaagaa
    23701 tacttggatg gttttttaat gtttcgaaat tcgtttttgc tcgatcaaga acagccgcct
    23761 gccactgagg tactgcacct ggtacgttgt aagaaggctc aaatgcgccc attttttgcc
    23821 atgagccatg ggattcgagg ttcgtttccg ccatcacatg gattcctgct tggtcgcata
    23881 aataatacca agtgatctgg ttggggtaat gagatgtccg tacgccgttg atctttgcat
    23941 tttttatgat agccaaatct ttttccatat cttctatagt gatggcgcgt ccttttttcg
    24001 gatgccactc atgtcgattt accccgttga taatcatccg ttttccattg aagtagatga
    24061 ttttatcttt gatttcgatt ttacgaaaac cgaaggaata gtcaatatac tccgttactc
    24121 ttttttcttc gtctatcgtc tccaattcaa gcttatataa attgggctga aaatgccccc
    24181 acagtgccac attttcaaat ccatcgatgc gaatcgtcat ttgctctttt aacggatatt
    24241 gctgttgata gatttccttc ccatcaggat ctagtatcgc tacattcagc tgactgtttt
    24301 tggctacttg ctcaaaagac aaatctactt caagtttgcc attttgacat ttgtcatcta
    24361 agcgaggttt gatccaaaga tcttctaaat ggttttgtcc tcgagcaact aagaagacat
    24421 ctctgaagat cccaaaaaat cggaaaaagt cctgatcttc caagaatgca gctgtacttc
    24481 ttttgtaaac ctccacagct agaatatttt cttcttccaa ataaggtgtt aaatcaaatt
    24541 cagacggagt gaacgaatct tcggcatacc cgataaaatg accattcaac caaataaaca
    24601 ttgcttgttc tacaccagca aaatgaatcg agatttgttt tccctttaga ccttcttcta
    24661 atcgaaaagt cgtcaaatac gaaccaaccg gattgtcttt agcagctgaa aagatccctt
    24721 ccgcctcttt ctcagggctt gtcgtgaaag ggggacggcg aaatacatgt ccctcccacg
    24781 gatacatcgt attgatgtaa tggatcttgt cataatttgc taattcaata tgactaggaa
    24841 cagtgatttc atcaaaagaa caggcatcaa aatctttttt ataaaatgtt tttggtcgta
    24901 ccgaaggatt tggcgaataa caaaaacgcc atgatccatt taaagactgt ttaagggagg
    24961 atctggtttc tacttcttcc cttgttgcat aacaaacatg atcgctatgt gcatttgatt
    25021 ggttcactct aaaaacttgt ggatcatcta accattttat atttgctttc atactttttt
    25081 ccttctctct cataactttt tgaaatgaag cagttctgtt tggaaatcac cttgaaaatc
    25141 ggggaagtaa agtccaactg tcatcaattc ggcccccgaa aatatccgct tcgaggtctg
    25201 ttcctgataa agtgcctcat catctaaccc catcagatat acttcatgga acgctggttg
    25261 agctgaagct agtatcctcc ctaaaaacac aatagcttca tcttgtttag gagacacaaa
    25321 catccatgcg gcaatatttt cttcaaaagg actcgccaaa cgataataat ggccatactg
    25381 gatcaccgga cgaatcgttt gataggatat aatttggtct tttacttgct tttcttcttc
    25441 aggagacagc tttgtcaaat ccagttcata accaaaaaca gcgctcatag ctgtttctcc
    25501 tcttgttttc aacgaagtag atctgtcggt ctgatgattt ggtacagctg atacatgagc
    25561 tgtgatggac gaaatcggat aagcaaggct tgttccatat tggattttca tacgctccac
    25621 tgcatccgtg ttatcacttg tccatgactg cggcatataa taaataaacc cggcatcaaa
    25681 ccgtccacct ccaccagaac agccttccca taagatttcc ggataatcag ttgtcaaatg
    25741 ttcaagtagt tcataaagcc cgagcatata acgatgcgct acttctcctt gtctctgtgg
    25801 gtcaagggta atcgaataga catctgaaag cgaacggttc atatcccatt tgatgtagtc
    25861 aagaggaatc gtatctaaaa tctttctcat ttgtttctca atcgtctgcc gaacatctaa
    25921 ccttgtaaaa tccagtacat gttgtgatct ggaagcagaa ggcattctac ctggctcctg
    25981 cataagaaaa tcaggatgtg ttcgatacag ttcagaatca accgagatca tttcaggttc
    26041 aaaccataaa ccaaatttca atcctttgct atgagcataa tctgctattt cacgtaatcc
    26101 atttgtcaac ttgccttcat actcgaacca gtctcctaat gaagaattgt ccgcatctct
    26161 ttttccaaac cagccatcat ctaatacgaa catttcgatg cctagctcct ttgcttcatc
    26221 aatgatcgcc ttgatttttt cactattgaa gtcaaagtaa gtggcttccc agttattgac
    26281 cagaatcggc cgttcagcaa attgatgacg acctcttgcg attctttcac gtagcaactc
    26341 atggtggatc tgactcattt tgttcaatcc ctgacttgag taagaaagga tcatttcagg
    26401 tgtttgaaaa gactggcctg cattcaattc ccacgaaaaa cgatggctgt tgatcccacc
    26461 gacgactctc aattgattga tctgatcttt ttcaagttcg aaagaatggt tgccggaata
    26521 aacaaattga agtccgatcg cttctccagt attttctgtc gtatgatgat gaactaaagc
    26581 aataaagtta ttcatatggt gactgctcgt tcctcgacgg ctttcaaata cttttgttcc
    26641 agataaaaca gattgccgtg aaatctgtct ttcattgaca tgtgctcctg gcaaagcaat
    26701 gacttcatca aatcgcctag tatgggcaaa gtctagctgg aaactagccg ctttttctag
    26761 tttgattgtt tctccggttt catttcttat ctttacagat cgtgtgatca ctgctctatc
    26821 agtaaatatg gtatagaaca aatcgaaata aatcgctgtt tctctatcct taagtgaaat
    26881 caccaacgtt tgtgcctctg acttgtccat cacataagtt tgaggcaagc cttcgatctc
    26941 tggcttccca tctgtaatat aatggctgtc atatctcaga tccagtaagt ctgatccatt
    27001 cttgcgctga atgatcgatg cgggcgttcg aaagtccatg ctgccatgag aagagtattc
    27061 ttgcggtagt gtatctttcg acagagaccg gtcaggattt aagggaacat ttcctgaaaa
    27121 tccacgatct cttcggggat aatttttatt gtctttgtac tgcttgactg gtttgccaaa
    27181 ataaatatgc gccaatacat tgctttcttc tatctttatc agataagaaa gaaatgtatt
    27241 tcgtaaatgg aagactcggc tcttttcatc aaataagatg aaatttttat ctgtttttct
    27301 atgcgtaata tccatcattt cactcccaac aaaacggaaa ccgtttactt ttttttataa
    27361 ttcctgtata ctgtttacta aacaattttg tcaataaaaa ttttttattt ttttgaggag
    27421 tgtgtaaaaa tggttggaat tagagatgtc gcacgaaagg caaatgtctc tcctgctaca
    27481 gtttcccgtg tgttgaataa cgatcagacg atccatgtgg ctcagactac tcggcaacgg
    27541 atagtagagg cagctgctgc gttggattat gacatcagta ctcgtaaata tatcaaaaag
    27601 agaatgcctt cgattggtgt gatctctacg atcggcaaag cgagcgaaga acaggatatc
    27661 tattacaaac atttgcgagt agggatggaa gaagaagctc gacgtctgca tttagggatg
    27721 aatcgaatct ataatctatc tgataatcct aaacaatggg aagatctaga tcagttaggt
    27781 gcggtgatcg ttgttgggac tgttacgaaa gaatcgatta ccgccttgtt aaaacaaaac
    27841 atgcaaatag tcgtcgtgga taaccctgac atccagcaag aggtcgatat ggtgtatgca
    27901 gatcttgaac ggatgactaa aaccgtactg gaattgttct tagaaaatgg tcataaaaga
    27961 atagcctata tcgggggata taaagtcgat atggatgaat tcggtgggaa gcagatttct
    28021 ataaatgaaa agaggatgcg tgcctatcag cattttatga tcgatcatca cttagaaaaa
    28081 tatatgtctt atcatctagg tggctggaca gaaaaacaag gtgaggtact tgcgactaat
    28141 ctattagaaa atgaatcccc tcttcctact gccattcttg tcgggagcga tccaatggca
    28201 attggtgtct atcgggcatt gaaacaaaaa aatatccaaa ttggagaaga gattgttgta
    28261 gcaagctttg ataatatcga gacaatcgca aacctctccc ctggcttgac cagtgttcaa
    28321 atcaatgcga aatcaattgg gcaagcagct gttcgaatgg cattggagcg aattgacggt
    28381 atacgggacg aaccaatcat tttgacttat cctgcacgat tgattgttag ggaaagtttt
    28441 atcccaagaa caaaaaggta ttgaaagaga ggttgtgaaa agccgcttcg tttcttcata
    28501 ctcaaaacga aacggctttt tcacaacctc ttacttatac ttattcacaa aatccaatgt
    28561 ctgctggtaa caattttgcg attcttttag cgtgtaatca aattggtatt catgggtaat
    28621 ctcttttttt gtatctgtat aaaacaagga ttgcacgggt acctttaatt ctgtcaaccg
    28681 attttctaat gcttgacctt gctcctggaa tgagtatgca tttccgtcag ttatatacgt
    28741 tggcggaaat tccttagaaa catggtcagc cacactagct tctttcaatt gctcactcgt
    28801 tttccaatct tttgttccaa tcaacgacca cgcaacggtt ttgacgaaaa acttcataaa
    28861 tcgatcatcc gaatgctgct gtgctgttag cttcaaatca acaggtccgc aataagaaat
    28921 ggttcctttc agactatctt ttggaagtag atgtttgatt ttcatttgtt tagcatacgc
    28981 atcattcgtt tgtatagctg catattgcaa tgcgatttgt gaacctgcac tatctccacc
    29041 aaaaaataat tgttccatgt ctagcaattt gtcgtctttt tcttcagcta ataaatcttt
    29101 gatcagttca ttcacttgaa gaacttgatt agggtattct gaatcaggcg ctaattcata
    29161 attcatcgca accactgcga tgttggcgtc tgaaactaat tttgtcgcaa attctttgac
    29221 acccgattta tctccgccga cgaatcctcc accatgtacc caaaatagaa caggaacagg
    29281 ccccttgctg ttttttggat agtagatgtc ataagtattc tctttatact tggactcata
    29341 cgtcaaatct gtttttttcg ccacgttttt ttctgcttga tcgaacgttt ttttatcagt
    29401 gatttgaaca gtatttgaaa acatatggtt gatcaagaat gctccaggtc tgggggaaag
    29461 ctggaaggca agaaagattg caaacgcgat cccaagaatg attccgaaga accatccgat
    29521 aaatttaaga attttctttt tcataaggct ccctcagtag ttagtattaa gcattctgat
    29581 tataccatag tgttatttcc tatcaagctc tcctagatga tttaatgatt ttccccaaac
    29641 ttcttctgca atgcttttga caaaagaaat tttttccatt gttcttcaaa caaaacattt
    29701 tcttcttctg ttgaagcaaa tccacattga ggacttaagc acaaacgatc caaaggcaga
    29761 tatcgtgtcg cttcgtagat ccggtcaatc acttgctggt gctcttccat ttcgccattt
    29821 ttcgttacag tcaaaatcta agacaactaa tttatcttca gagactttct ctaaaagaac
    29881 aaaactccca gcacgttcac tatcgtattc taaataatag gcacggacat tttcttgagt
    29941 aaaataatgg gtctgctacg tcgtcatccc ccctgatgcc gccaaaatcg aataataatt
    30001 tccgcgtcaa acatgtatat ttagtgttga atcatttgag aatatgaaaa taaaaatctt
    30061 tttgatcaat cagttaatca aattgaaata acgaaaaatc tgagacagaa tgacgttcat
    30121 tctgacccag atttgatttt gcacaactca acagtcctta ttggcaaatc gccaaaataa
    30181 tgtagactaa ctaaaaagac taagaaacaa taacaaaagt taacacttct tagtctttct
    30241 ttagcacgtc tatttattaa agattttagg gccttttctc atgtttttac gatcattctt
    30301 aggtgtttcc atttgtttgg atcggcctcc accttgtttc tttttgatca attctttcat
    30361 tttttctttt tggtccattt ttattctcct ttaacgaatg aagcgactaa ttcgatatga
    30421 tgggtttgcg ggaaaagatc tacaggctga actttcttca cggcataacc tgcttctgca
    30481 aataacttag catctcttgc aaaagttgcc ggattacatg agatatagac gattcgttct
    30541 ggtgacattt cgattgctga ttcaataaaa tgatgatcta atccttttcg tggagggtca
    30601 actacgatca cagatggttt gatccctttt tcttgccatt ttttcataac tttttctgct
    30661 tttccgactt cataatgaac attttcgatt ttattattta aagcattgaa ctgtgcatct
    30721 tcaattgctt ctggaataac ttccatccca tacaccttat ccactctgtc tgctaaagac
    30781 aagccaatcg tacctattcc tgaataagcg tcgatcacaa tgtctttttt atctaactcg
    30841 gcaaactcga tggctgtttg gtacagatac tctgcttgtt gagtatttac ttgataaaat
    30901 gactttgctg agattcgata ggtttttcct aatagctgat cttcgatata gtctctgcca
    30961 tataaaactt tttctttgtc tcctaaaatc acatttgttt tttcttcatt gatattttgg
    31021 atgaccgaaa ccacttctgg caattcttca tgaatagctt cagcaatttc cttggattta
    31081 aagaattttt ctttacgagt aactaaaacg accatcattt catgggaata atgaccacga
    31141 cggataatga tgtgacgaag ctgtccttca tttttttctt cattatatcc tcgtacttgg
    31201 aaccgttgca agatatctct gactactttg attgcttgat cgatgacagg atcttggata
    31261 taaaaatctt cgatagggac tagatcatgg ctattctttt tgtaaaaacc ggtggctaac
    31321 tgtccatcga tacggcgaac agggatctgt gctttattac ggtagccgaa tggttctgcc
    31381 attccgaccg ttggaagtac aggaacttct ggcatcttag caatcttcgc cattacatgc
    31441 tctacttgtt tttgtttgaa gacaagctgt tgttcatact tcaaatgggc taaaggtgcg
    31501 atacctatgc gaagtaatgc attgttttct acaggctgac gatcaggtga ttgtgtaata
    31561 aatgtttcga cttttccata tccaaactta ttgcctgctt ttactactag tatttctact
    31621 tcttctccag ggagtgcatt ttcgataaat aatggataac catcgatttt tgctaccccc
    31681 attccttcat aactcaagtc gacgatttcg actgtatatc gttcgttttt ctttactatt
    31741 tgctgttctg tcatattttg ctcctttaag cctatttttc aatcctactg aactctacta
    31801 taaatcagct aattacacaa ctaaaaccgg cactgacctt actacgttca gcaccggctt
    31861 ttgattaatt cttttgatta ggtgtttcgt ctgctatttt tccgtcaccg tcgatatctt
    31921 catccgttaa acgttcgact tcttttacga attctttgct gacaacctct aattcttctt
    31981 catctgtacc tgtgattgct tcatcaggaa tctgatcggt attggcaaag aactcaatgt
    32041 gttgatgaag attttggaaa tgcatcggtg cttccccgcc gtattcacca tctaagttga
    32101 tcattactgg tcgattgata tcatcttctg tttcaacgaa caaactgctt gttttggtat
    32161 agattattct tggatcatcg acatgtcgac cgccattcag catgagtgct gcaatatgca
    32221 agatctcaaa gatatttgct gtcttcacaa tgattaaaga aaacttccca tcatccaatt
    32281 tggcatctgg cgcgatctgt tcgaatcctc caacagagtt cgtcagccct aggaaaaaca
    32341 tcgaagcatt tccgatatat tccccttcat catacttcaa gcgcattttg attggcttta
    32401 ctcgagggag catctctgct cctttcgcaa gataagcaag ataaccaaaa atactcttta
    32461 gttctgatgg aacttcataa gtcaattctg tcaaatagcc acctgcagcg atattgatga
    32521 agtaactgtt atcagaaagg ccgatgtcca tttttacggt ttggtgtttt tttatcactt
    32581 ctgctgctgc tttaatatta tctctaggaa tttttaatgc tcgagcatag tcgttcgttg
    32641 taccagctgg gatgatggcc attttaggac ggtgttcaag cggagcgatt ccattaacca
    32701 cttcgttgat tgtgccatcg ccaccagctg ccactactag atcaaaacct agttctgcga
    32761 ctctacatgc ttcattcttg gctgaatctg gttctggtgt agttgcatag gcgctggctt
    32821 caaatcctgc ttcttctaat gcctgtagga tatccgccaa attttttttc aataattctt
    32881 ttcccgaggt ggggttataa attacgcgtg cttttttcat tttcagcctc tatcgtttcg
    32941 ctaattcatc tttaagtagc ttattcacga caccaggatt tgcttgtcct ttagttgctt
    33001 tcatgatttg accgactagg aagccaaccg cacgatcttt tccatttttg aaatcatcga
    33061 cagattgttg gttgttatcc aaaatttcat taatgattgg cagtagtttg ttcggatcag
    33121 ataattgcac ccaaccattt ttttcaacta cttcttgggc ttctccgcca tttgtgatca
    33181 attcacggaa gacttttttg gcgatttttg agctgatcgt tccatcggcg atcaaacgaa
    33241 tcattcctgc taagttctca ggtgtcaatt ttgtctcagc taattccagt ttctcactgt
    33301 tcaagtaagc agaaacttca cccatcaacc agttagatgc ttgcttggca tctgcaccat
    33361 tttccaaaac agcttcaaaa aaatcagaca tttcttttgt aagtgtcaat accattgcgt
    33421 catactctgg aagtccaaac tcacggatat agcgttcgcg acgagaagct ggcatctcag
    33481 gcaaactagc ttttactttt tgaatccatt cgtcatcgat cacgaatttc gggatatcag
    33541 gctctgggaa gtaacgataa tcactagacc cttctttgac acgcatcaaa actgttttat
    33601 tcgttgtttc gtcaaaacgg cgtgtttctt gttggatttc tcctcctgaa agaagaactt
    33661 ttgcttgacg tttttcttca aaagctaaac cttttttcac gaaagataaa gagttcaagt
    33721 ttttcaattc tgctttcgta ccgaactctt cttgtccata agggcgaaga gaaatattgg
    33781 catcacagcg catagagcct tcttccattt tcacatcgct gacttctgta aattggataa
    33841 ttgatcgcaa tgcttctaga taagcgtatg cttcttctgg tgaacgcata tcagcttcag
    33901 aaacgatttc gatcaaaggc gtgccttgtc ggttcaaatc aacgtaagaa taaccgccaa
    33961 taccatgcat gttttttcca gcatcttctt ctaaatggac acgttcgatc cggatttttt
    34021 tctttttacc ttctacttcg atttcgatcc atccgtcatg accgattggt tgatcaaatt
    34081 gggaaatttg atatgctttt ggattatctg ggtaaaagta atttttccgg tcaaaatgag
    34141 tatctttaga gatttcacag tttaatgcca aagctgcttt catcccgaat tccagcgcag
    34201 ctttattcat tactggcagc acgcctggat aaccccagtc gatcacgttt gtattgctgt
    34261 ttggttctgc accaaaatga gctggcgctg gagagaaaat ttttgagttg gtttttaact
    34321 cgacgtggac ttctagtcca atgactgttt caaaattcat tcgtctttcc ctcctaaaat
    34381 agctggttgt tgtttatgga attctgttgc ttgttcaaac gcatatgccg cttgatacat
    34441 cgttttttca tcaaaataat taccgatgat ctgcaatcca actggtaatc cttctgataa
    34501 acctgccggt acagacatac ctggaagtcc agccaagttg acagggatcg ttaagatgtc
    34561 actcatgtac attgtgattg gatcgttaat gttctcaccg attccgaatg caactgttgg
    34621 tgaagatggc ccgatgatca agtcataatc tgcaaagact ttttcaaaat ctcgtttgat
    34681 caatgtacgg acttgtcctg cttttttgaa gtaagcgtca taataacccg cgcttaagga
    34741 gaatgtacct aacatgatac ggcgttttac ttcttcaccg aatccttctg aacgtgagtt
    34801 gacatataca tcatctaatg atttcacatt ttcagagcga taaccgtagc ggataccatc
    34861 gaatcgttgc aaattggaac ttgcttctga tgaggcaatg atataataaa cagccacacc
    34921 gtattttgaa tgagccaagc tgacttcttc cacaacagca cctaatgaac ggaatgtttc
    34981 tgctgctttc aatacagctt cttttacgcc aggggccaca ccttcgccta agtattcttt
    35041 aggtaaagca atcttcattc ctttgatgtc gcctgtcagt ccctctgcaa aatcaggaac
    35101 tgaaacgcct gaagaagtac cgtctttttc gtcataaccg ctgatagctg tcaatgctaa
    35161 tgcattatct ttcaccgtac gggtcattgg tccgatttgg tcaagagatg aagcaaaggc
    35221 aatcaaacca aaacgtgaga cacggccata agtaggtttc atccctacga tgccgttaaa
    35281 agctgctggt tggcggatac ttcccccagt atcactacct aaagaaactg gaatttgtcc
    35341 agctgcaact gctgctgcag aaccaccaga agagccacca ggtacttttg ttgggtccca
    35401 agcatttttt gttttcttga aataagaagt ttctgtactt ccacccatag caaattcatc
    35461 catgtttagc ttaccaacag ggatcatatc tgcttgatag attttatcca tgaccgttgc
    35521 atcataaatt ggttcaaaat tgtaaaggat cttagatgca gcggttgtca agatatcttt
    35581 tgttacgata ttatccttga taccaattgg aataccagca aggacgttgc tttcatcaat
    35641 ccctttttca tctaaagctt ttgcctgttc caatgctttt tcttcgttca atgtaatgaa
    35701 tgcctcgacc tcaggctctg tttctttgat tcgttcaaat gttgtttttg tcaaatcttg
    35761 tacagtgatt tctttcgata caagcatatg atgcagttct tctagagaac gattgtgtaa
    35821 ttctgtcatt atgcgccagc ctccccatta tcgatgattg cgggtacttt gataaagccg
    35881 tcttctgttt ccggcacatt tttcaataat tcatcgcggt tccatccagc ttgcgcccga
    35941 tcttgtcgca tcacgtttac tgtttcaacc acattcgacg taaatggaac accttccgta
    36001 tctacttctt ccagcatttc aaccatatcg atgattttac ctaattggtc ggtaaaactt
    36061 gcaagttctt catctgcgaa cgcaagtttt gctaatttgg caacgtgttt cacttgttct
    36121 tcactaatcg ccatactacc ccttctttct aaacgagtta aaaactttgc tctctatttt
    36181 aacacaagag tgccgtgtct gaaattgttt attgaaattt gtctgaaaaa actcattttt
    36241 cattcttcta ctgagcgact tttagccaat gcatctgcca tttgatcttc tgtccaaact
    36301 tcgattccta attcttgtgc tttggtcagc ttgctgccag catcttctcc tgctaccacg
    36361 atatccgttt ttttcgatac gctaccagtc actttcccgc caagattttc gatcgtctct
    36421 tttgcttctt cacgagtaaa tcgtgttagt ttaccagtaa ggactactgt tttttcttta
    36481 aaaggagact cgacttcttg caattgggca tttcgaagcc ctttgtattc gaaattgacg
    36541 cctgcttgtt ttaattcatt catcaattca tggacttctt cgttactgaa ataagtgact
    36601 acactgtcgg caatgatatc accgatcgta tcaagcgcaa taatcgactc atagtcactt
    36661 ttactcaatg tttctagatc accgaaatgt tctgctaaaa tttttgctgc tttcgctccg
    36721 acatgtcgga ttcctaaccc gaaaatcaac cgctcgaccg aattatcttt gctgttgtcg
    36781 attgctgtca aaatattatt tgctgatttt tcttttattt tgtccaacgt caataactct
    36841 tcttctgtca atttgtaaag atcagcaaca tctgctacta gttttttatc atacatctgt
    36901 tctagtacgc gcggccccaa cccatcgata ttcatcgcat ttcttgaaac aaagtggttc
    36961 aaaccttctt tcatttgagc agggcattta ggattgatgc accgtaaggc tacttcttca
    37021 tccaaatgga caagttcact tccacaaact ggacaatgtg taggcaattg gtattcttcg
    37081 ctgtctttag gtcgtttatc taacacgact tgcgaaactt ctgggatgat gtctcccgct
    37141 ttataaatca gaactgtatc tttcaagcgg atatccttca acttaatata atcaccgtta
    37201 tgcaggctgg cacggcttac tgtcgttcct gctactcgga ctggtgtcat gatagctgtt
    37261 ggcgttacta cccctgttcg accgactgtc cattcgatgt tttcgattag cgtttcaact
    37321 tcttctggcg gaaacttgta agctgctgcc catctcggtg ctttgatagt aaaaccaagt
    37381 tgatcttgta gcgagaattc attcactttg atgacgattc catcgatttc atagggcaaa
    37441 tccacacgtt tgtcatgata ttcttcaatg tatgaccaca cttcatcaat cgaatgacat
    37501 agacgttttt cccgattcgt gtggaatcca attttttcta gctcttctag cgcatcatac
    37561 tgggtttttg cttgcatagg accgaaatca gctactgtgt ataaaaaagt gtccagattt
    37621 cttttcgctg tgattttaga atctaactga cgcaaagaac cagctgcggc gttccgagga
    37681 ttcgcaaaga tatcttttcc ctctgcttct ctgtcttggt tcaattggac aaatgaccgt
    37741 tttggcatga aacattcgcc tcttacttcg atgttcattg gttcttttaa tttgattggg
    37801 accgaccgga cagtttttag gttttcagtg atgttttctc ctacagttcc atccccgcga
    37861 gtcgcacctc tcacgaaatt tccatcttca taacgcaaag aaacggaaag tccatctatt
    37921 tttagttcac agcaatagtc aactacacgt cccactgctt tttgtacacg ttgatcaaaa
    37981 gctatcagct cttctttgct gaaaacgtcg ttcaaactgt aaagcggaat atcatgagtg
    38041 actttttcaa aaccttctaa tacttttccg cctactcgtt gagtgggaga atcagacgtg
    38101 atcaaatcag gatattgttc ctcgattgct actaattctg cgtattcttt atcataaaca
    38161 tagtcttcca ctgttggttt atcttctacg tagtattcgc gagaccattg gttcagtctt
    38221 gtacgaagtt cttctgctcg tttagcagct tcgtcaatcg tcatttcatg ttccatcatt
    38281 taccctccac tactaagctt tttcaattgg cgcaaaggca gccaaaagac gttttactcc
    38341 ttgacttggg aaagccacat ctagttctag atccttcgac gtcccgctta ctcggacgac
    38401 tgttcctaga ccccattttt tgtgtttgac tttatctcca ggtttccagc tgttattttc
    38461 ccctccagta gcacttttag agggaacaac cgctgtctct ggctgtttat agctatatgc
    38521 tgttttttta gcgaatacag gcgttttttt aggcgtagga cgcatgcctt cgatttccag
    38581 taactcctga tcgatttctt ctacaaaacg agaaggtcgg ttatattgcg tccgtccata
    38641 taatgttctg gagaaagcat ttgttaaata caacgcttct tctgctcgcg tgatccccac
    38701 atatgcgaga cggcgttctt cctccagttc gctttcttcc atcaatgctc gagataaagg
    38761 aaaaaccccc tcttctagac caatcaggaa tacaactgga aattctaatc ctttggctgc
    38821 atgcaaagtc atcaatgtca cttgggaagc atcttcttct aaattgtcaa tgtcggaaac
    38881 aagtgccaga tcatttaaga agaccgttag tttttcttct ggtgcatcag cgtcttcttc
    38941 attttgctgt tcgaattgtt tgtcgaattc ttgtgtgacc gttaaaaatt cctccaagtt
    39001 ttcgatgcgt gcttgtgctt ctaatgtatt ttggattttt aagtcttcta gatatccgct
    39061 acgatccaaa acctctttcg tcaattctgt cactgtcaag tatgggatca tctgagtgac
    39121 ttcttggatc atctctccaa atgcacctaa ttgctgtcct gcttttccac cgatatttgc
    39181 cagatccaca ttttgcgctg cttcaagcag tggccattca tgaagagaag caaaactgcg
    39241 tagtttttcg atagatcctg gtccgatgcc tcgtttgggc gaattaacga tacgctcaaa
    39301 actgattgaa tcttgaggat ttaccagcac attcaaatac gctaaaatat ctttgatttc
    39361 tttacgatcg tagaacttgt gccctccaac cattttataa ggaatatttg ctttcaacag
    39421 agtttcttcc attacacgag attgtgcgtt cgtccggtac aagatggcaa agtcgccgta
    39481 attccgatga ttgcttcgaa tctcttcttg catccggtct acgataaaac gggtttcgtc
    39541 tcgttcatta tctgcacggt agtaagtgat cttgtttcct tctttgtttt ctgtccacaa
    39601 gttttttggt tttcgattgc tattgttttc aatgacttgg tttgctgcgc taaggatgtt
    39661 tttcgtggag cgatagtttt gttctagcaa aattactgca gcatctggat aatctttttc
    39721 aaaatccaag atgttctgca tatctgcacc gcgccagccg taaatacttt gatctgcatc
    39781 tcccacgacg cacaggttcc taaatctacc tgccaataaa ttgactagcg tatactgtgc
    39841 gtgatttgta tcttggtact catctacatg aatataatgg aatttgtttt gataatacgt
    39901 gagtgaatca ggatgttctt caaataatcg aatcgtattc atgatcaggt cgtcaaagtc
    39961 catacattga ttatattgaa gctctttttg gtaagcagca taacattttg ccgcaatctc
    40021 ttcgtaataa ctgccttgca tttttgcaaa atcctgaggg gtctgcaggc tgttttttgc
    40081 ttgagagatt gttcctaata tacttcgagg atcatatttt ttcggatcaa tgttcagttc
    40141 ttttagtatc cgtttcatca aggtcagctg ttcagaagaa tcgatgattg taaagttccg
    40201 gttatacccg ataaaatcaa catctcttct taaaatacgc acacacatcg agtgaaaagt
    40261 cgatacccag acatcttcgc ctccagatgc gagaatcgca ttgacacgtt ctttcatttc
    40321 ttttgcagcc ttattggtaa aagtaatcgc taggatgttc caaggattga cttctttttc
    40381 ctcaatcaaa taggcaatgc ggtgtgtcag cactctcgtc tttccacttc ctgcacctgc
    40441 cattagcagt aatggtccgt cagtgtgaag aacagcttct ttctgacggg ggttcatccc
    40501 gtttaataat tcagctttgg atgacattaa caacatcctt tcttttatca atcttgttaa
    40561 ttatagcatt ttcttggctt tcattaaact agctagttca aaatcatttg tttcttttta
    40621 tggatttttc cttgtcaatt cgttgatttc gcgctaaatt aaaagaaagc gaggcgtttg
    40681 aatggaaaaa aaaggaaaaa tcaagaaatt agataagact cagatatatt ttattctaaa
    40741 aggaatattt gttggactgc tgacaggaat cgtcgttagc ctgtttcgat tatctatcga
    40801 aaagctaagc gatttagttc gaagtatcta tgaaatgagt cgggaacagc cgatttactt
    40861 aattggccta gctatttgct gcatccttgc agcatttttc gtgggttatc tggtcaaaaa
    40921 tgaaccggat atcaagggaa gcgggattcc acaagtagtg ggacagcttc gcggggaatt
    40981 atcaatgaac tggttctctg ttttatggaa aaagttcatt ggcggtgtac tttcagttgg
    41041 tgcgggcctt tttctaggta gagaaggacc ttctatacag cttggcgcat ccattggaca
    41101 aggagctgga caattgtttc ggagtccatc ttcagaagaa aagattttaa tttctagcgg
    41161 tgcaagtagc ggacttgcag cagcattcaa tgctcctatc gcaggattac tctttgtttt
    41221 agaagaaatc catcactcct tttctccact tgtttggctg acatcatttg cttcagcaat
    41281 cactgctaac ttcgtctctc tttacttttt cggcttgaga cctgttttat atctaggtga
    41341 ccttccttct ttgccgttga aatattatgg ttccttagtg atcttaggag tacttctagg
    41401 catcttaggt tttatttatc agaatgtctt gctggctttg ccaaaatttt acaaccgatt
    41461 gcctttacca gcttattttc acgggttcgt tcctttcttg ctgattttgc caattggtta
    41521 tttatggcct agtactctag gcggaggcaa tcaaatcgtt ttagcttttg gacatgcttc
    41581 cttgccaatc attatgatta tcggtttgtt tgttcttcga ttcgtttttt ccatgatttc
    41641 ttacggtggg ggtcttccag gggggatttt ccttccgata ttgacattgg gggctttaat
    41701 cggtagcttt tatggaaaca ttatggttga tttcgggatg gatccaatct acatcaagga
    41761 ttttgtcgtt attgccatgg ctggttattt cacagcgatt ggaaaagcac cgctgacagc
    41821 aattatttta gtgacagaaa tggttggctc tcttaatcat ctgatgcctt taggattggc
    41881 tgctcttgtt gcttatatcg tcaatgacct tctcggcggt aatccaattt acgaatcatt
    41941 attggaacgt ctacttggaa atactcagac cgcctcacta aaaggtgcaa ggacaacttt
    42001 tgattttcca gtaacggcag agagttcttt agacggatta atggtacgag acttcaattg
    42061 gcctaaaaat atgctgctaa tctctatacg cagaggaaat caggaaatct tgactcacgg
    42121 tgatacgatc atgaatgtag gagatatttt ggttatcttg actgatgaag caaacttgcc
    42181 aagaatcaag caggaaatcg aggctaaatc ttctatcaca aatttgaagc aatcatttta
    42241 acgaacatgg aaaaactatt ttacaacaac tattcatcta cactacttga ttctatatga
    42301 ttctat
//
LOCUS       DAFBVQ010000016        41266 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.016, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000016 DAFBVQ010000000
VERSION     DAFBVQ010000016.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.016"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            214..498
                     /locus_tag="LLC22_001066"
     CDS             214..498
                     /locus_tag="LLC22_001066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328758.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1905 domain-containing protein"
                     /protein_id="HBK5434359.1"
                     /translation="MREIYSFESKIYASEVGKGGAYIIFPYDIRKEFGAGRVKVQATF
                     DNVPYEGSIVNMGVKNPDGSVCYILGLRKDIRKNIGKEIGDIVAVTVKQK"
     gene            complement(779..1198)
                     /locus_tag="LLC22_001067"
     CDS             complement(779..1198)
                     /locus_tag="LLC22_001067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312785.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid decarboxylase"
                     /protein_id="HBK5434360.1"
                     /translation="MEKETIVEVTKLGFTIQAAVKVIGKDLLITLTGGDTPHIGTVTT
                     FSRDTEMQTVRFPSHDGRFHKDDVLAEKIAVIIKTAVPGSCTITSGIHVDHISNAQIN
                     ASFPMSEELGYKILDWLEKIDFHIKEPVYYKDGEKPL"
     gene            complement(1200..1784)
                     /locus_tag="LLC22_001068"
     CDS             complement(1200..1784)
                     /locus_tag="LLC22_001068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiX family flavin prenyltransferase"
                     /protein_id="HBK5434361.1"
                     /translation="MEQLAQRKKKIVIGVSGASGTIYAINLVKKLKEYPMIETHGIIS
                     PWAKQNLKLESDLSLTEFESLFDYHYSNKDLGAAVASGSFLTDGMIIVPASMKTVAGI
                     SVGLGDNLIARAADVTMKEQRKLVIVPRETPLNAIHLENLTKLARLGVQIIPPIPAFY
                     NQPQTIQDLVNHHTMKLLDQFEIVNEHSKRWQGD"
     gene            complement(1831..3306)
                     /locus_tag="LLC22_001069"
     CDS             complement(1831..3306)
                     /locus_tag="LLC22_001069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UbiD family decarboxylase"
                     /protein_id="HBK5434362.1"
                     /translation="MTDQPYDLRKVIEELKTLPGQYHETDIEIDPEAELSGVYRYIGA
                     GGTVKRPTQEGPTMTFNNIKGFPGTRVNIGTMASRKRVGEILHHDYRTLGRFLKDAVE
                     NPIKPVKVDKADAPAQEVVHLATDADFDIRNILPAPTNTPEDAGPYITMGVVLGSDPE
                     KTMSDVTIHRMVLEDKDTIGMYIMPGGRHIGHFQKQFEALNKPMPITINIGLDPAIAI
                     GTTFEPPTTPLGYNELWCAGALRNEPIQIVDGIAVDEVGIARAEFIIEAEIMPNETMQ
                     EDINTNSGKAMPEFPGYTGDANPAVQVVKVKAVTHRKDNPIMQTTIGPSEEHVSMAGI
                     PTEASILALVDKAIPGKVVNVYNPPAGGGKLMTIMQIRKENEADEGIQRQAAILALSA
                     FKELKTVILVDEDVDIFDMNDVVWTFNTRFQGDKDIIVIPGMRNHPLDPSELPEYNPG
                     SIRFRGISAKTIFDGTVPFDMKEHFVRAKFQEVEDWEKYLK"
     gene            3487..3798
                     /locus_tag="LLC22_001070"
     CDS             3487..3798
                     /locus_tag="LLC22_001070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434363.1"
                     /translation="MKKMEESFPKAVKVENIANILKVTFENGEVKYVKSHWTEEITDA
                     LQFGKKGRGKRKNLLALSRNMWIGTEVTIEADGTVFINGKDRYTPEELWYKGKKSIPE
                     L"
     gene            complement(3913..6249)
                     /locus_tag="LLC22_001071"
     CDS             complement(3913..6249)
                     /locus_tag="LLC22_001071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5434364.1"
                     /translation="MLQLKDIKKYYKVGETTTKALDGVSVAFRQKEFVAILGPSGSGK
                     TTMLNVIGGLDNYDSGDMVINGKSTKDFKDSDWDAYRNNSIGFIFQSYNLIGHLGIIE
                     NVELGMTLSGVSKDEKRKRAEDALHRVGLTNHMHKKPNQLSGGQMQRVAIARALANDP
                     DILLCDEPTGALDTETSIQIMELIQELSKEKLVIMVTHNPELAHQYADRIIEFSDGKI
                     LTDSHPHIERPKDDQFNLRRTKMSFWTALKLSFNNIRTKKGRTFLTSFASSIGIIGIA
                     IVLSLSSGFQKQIDNTQAETMAKFPITISKVTTNQTRDDAGLGASKADYPDSKTITAK
                     VSEEDKAQHTNKIDQTYVDYVTDIDPNLSNNIGFTRTTGINLLRDVNGKVQPVSFSNQ
                     NPDTESLSLSSTMSAMTGVGVSSFPTQLDTSKENFLKDNYSLLAGSYPASATDVVLIV
                     DGNNNTNINALKNLGFDVKEDEKLDFDDIVGTTFKLVNNNTYYTKLPTGNFIPNTDYD
                     AMYQNASDELKISGILRVKSSSTMNLLSPGIAYSDQLTTQIVNENKESEIVKAQRDSG
                     VNVLTTEKVDENAKQTLLSYLGGDSLPSSIMIYPNNFEDKEKILDYLDDYNKGKSDED
                     KIIYTDLAGTMTELTGGLMDAITYVLIAFAGISLVTSMIMISIITYTSVIERTKEIGV
                     LKALGARKKDITRVFDAETCILGISSGILGVFIAWLATFPINSILYNMTDLKNVAQLN
                     PVHAIILVIVSTILTMLGGHLPARMAAKKDAAIALRAE"
     gene            6391..7059
                     /locus_tag="LLC22_001072"
     CDS             6391..7059
                     /locus_tag="LLC22_001072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5434365.1"
                     /translation="MNRILVVEDDPQLQLLYRSVLERAGFSVITALNGEDALKKLEAT
                     RIELIITDIMMPKMDGYDLLDSLRSTRFDTPVLMITAKADFEDKKRGFKLGADDYMTK
                     PIDVNEMILRVEALLRRSKINYSSSLIIGQTKLELDAYTVLQDQHSLILPQKEFLLLY
                     KLLSYPNKIFTRQQLMDDIWGLDTNTEERTIDVHIKRLRTRFEKTEDFQIITVRGLGY
                     KAVI"
     gene            7062..8105
                     /locus_tag="LLC22_001073"
     CDS             7062..8105
                     /locus_tag="LLC22_001073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5434366.1"
                     /translation="MKKKLFSQLWIYFASIVFISILVTLLCFLGFIFLLSRHSISPAE
                     SAGKPTLYPLFVFAGFSMVVGTGISIFVGRRILHPISALGTNMSLVATGDFSIRMDEQ
                     QKVAEVQQLYKDFNVMVQELNSIETLRNDFVSSVSHEFKTPLATIQGYVQLLQAPNLS
                     DEERQIFLYRIIESITQLSQLTENILKLNKLENQRIQLEKKEYRLDEQIREVIVFFQP
                     KWEKEQLELDIELAAVNYTGNEEFLYQVWLNIMDNAIKYNQINGQIHIKLFETATEIV
                     LEVTDSGVGMNEETRDRMFEKFYQGDTSRQISGNGLGLSLVKKILELHDGRIDYSSIE
                     GVGTTAMIRLSKQ"
     gene            complement(8342..9223)
                     /locus_tag="LLC22_001074"
     CDS             complement(8342..9223)
                     /locus_tag="LLC22_001074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5434367.1"
                     /translation="MDIHKFEVFLDLAETMNFTKTADRQFTTQGNISKQILSLETELD
                     VKLFERAHRKIELTEAGSLLLPYVKNVVEQYHAMQEVLETYTKDNNLSLNILTIPTMI
                     NYKGFSKITEFLKRHPEFTVQLKEVESVELTYNDANEHSDTIHFARSFQAPPSSIEWL
                     PTETDDFVAVLPKNHPLASKKKLDLSELKKENFLLLGPTTNLYQPVLDLCREAGFEPK
                     ISYKGARIDLIINMIANDMGIAIVMEKTVKNLLKENTVILPISPTTESYLAFTRKVGE
                     HSLASDTFWEYLNQEEN"
     gene            9382..10110
                     /locus_tag="LLC22_001075"
     CDS             9382..10110
                     /locus_tag="LLC22_001075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF554 domain-containing protein"
                     /protein_id="HBK5434368.1"
                     /translation="MPTGVLINVGSVLFGGLIGGLVGNKLSEHFKAQLTMVFGVCSMG
                     MGIYSIAPMKNMPAVIFALVIGTAIGLIVHLGNGINKGAALMQVPISKIFPSEKLGMT
                     HDEFISTLVTVIVLFCASGTGIYGSLDSGMTGDSTILISKSVLDFFTAAIFACNLGYV
                     VSVIAIPQFIIFYILFLLAKFIYPLTTPDMILDFKACGGFLMVATGFRMINVKMFPVA
                     DMIPAMIVIMPLSWMWTNWIMPLL"
     gene            10266..10583
                     /locus_tag="LLC22_001076"
     CDS             10266..10583
                     /locus_tag="LLC22_001076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5434369.1"
                     /translation="MHIQIPTVLLDGTVLAALSKEDMYGYALTKIVQESLSVSESTLY
                     PVLRRLKKEGYLETYDEPFEGRNRRYYSLTPMGSRHLEEIIDEWIVFRDSLDRLLEES
                     TNE"
     gene            10576..11184
                     /locus_tag="LLC22_001077"
     CDS             10576..11184
                     /locus_tag="LLC22_001077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1700 domain-containing protein"
                     /protein_id="HBK5434370.1"
                     /translation="MNEYLNEVVDHLQEIPEDDRFDLIQYYEEYFLDSGKTLDQIIDE
                     YGTPKQFALKLKISYFSEEEQAENELVKNPKRQIRLVWLIIIGLFASPVLIPLALGFI
                     LVIGGLLVALLALIFSIYVLCISILGVGLFMIISGISVFGQSILSGLFFIGVGLFATG
                     SAVFISPLLLKGTKGLFYVMMNFVKWMGRRFITKRDLHSAGV"
     gene            11239..12030
                     /locus_tag="LLC22_001078"
     CDS             11239..12030
                     /locus_tag="LLC22_001078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4097 family beta strand repeat protein"
                     /protein_id="HBK5434371.1"
                     /translation="MLTGGLLAGATYTLGAQKSLTWDNGPRLIDMVTETKKIKDANKI
                     VIHAENQTVSVIRGLDFEIKTTYDKTEKPEIKEKNGVLTVNAVKKSTGAIISLEDTSA
                     QITIVVPADHELSELTIEGNNSAIDINEVSIKKVNTKTHDGWVSFNEFTGGTITAKDE
                     LGSLRLDEANVDNLIVTGENSNFHLEDSLISKEGKVILNGGNLSLHEMENSGYTIQTS
                     GESYIEKDYQPITNTLLEQGQKKLKITAKDTSINITTDQEDNETD"
     gene            12168..12656
                     /locus_tag="LLC22_001079"
     CDS             12168..12656
                     /locus_tag="LLC22_001079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286309.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5348 domain-containing protein"
                     /protein_id="HBK5434372.1"
                     /translation="MKVEEGQREKLKTEMERLHTYITQLSQTFYDPDKEKVMVNYPNN
                     SEGRQLEQVYHEVFKHLLTVKKELDYYSLPIIDTGILKYDGKKERFIFKSVREDLPLS
                     AGMDLEVLVEDYFTEEKHWVRTKLDYLPQAAGGTQASGWYITEDKELELEGVMARIRK
                     KN"
     gene            12707..13579
                     /locus_tag="LLC22_001080"
     CDS             12707..13579
                     /locus_tag="LLC22_001080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBK5434373.1"
                     /translation="MREKRAFYINGYAGIVGLVVLALVGLFFFYLGMWQAKVWALFLS
                     IFLWLITLLLLSSATVVSPNQAKVILFFGQYLGTIRENGFFLTIPLAQKMTVSLKVRN
                     FNSSVLKVNDLDGNPIEISAVVVFKVVDTAKALFDVAYYQDFVEIQSETAIRHIASQY
                     PYDTFNENDLTLRGNTTAVSDELQKELQERLAVAGVEVIETRLNHLAYATEIASAMLQ
                     RQQAKAILSARQTIVEGAVTITQMALEQIEDGQEINFTDDRKVQLINNLLVSIITDKG
                     TQPVINTGDMKDRK"
     gene            13755..14117
                     /locus_tag="LLC22_001081"
     CDS             13755..14117
                     /locus_tag="LLC22_001081"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5434374.1"
                     /translation="MKKLLIGLLVFIVVVLAGVKIADYVVMGGEEYYVQITTDGTKTV
                     SKSDSGQETVNYRYILPGYTKEGKEKELDFKGQLTRPLRKGAYLKITWNKNKGVTSYE
                     EVEKKDVPKTALEKLIKG"
     gene            14126..14878
                     /locus_tag="LLC22_001082"
     CDS             14126..14878
                     /locus_tag="LLC22_001082"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434375.1"
                     /translation="MNKIVEVQNVTKVYGKNNEKKTQALSGISFDVEKGEFIGIMGAS
                     GSGKSTLLNILSTLDKPTDGHIRINQKDVTTLKGNQLADFRANEIGFIFQDFNLLESL
                     TAQENIAVPLSLQGVRPKEIKQRVQKIAERLSISHILESYPSEISGGQKQRVAAARAL
                     ITQPTILLGDEPTGALDSKSARDLLDTMDELNTKDHVSILLVTHDPFSASYCQRILFI
                     KDGGIHQEVKRGDQSRDSFYREILSILGNLEQ"
     gene            14892..16694
                     /locus_tag="LLC22_001083"
     CDS             14892..16694
                     /locus_tag="LLC22_001083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434376.1"
                     /translation="MLWKLSLTGIKSRLRDYLVLFSGLVMASAIFYMFESMASNEAFL
                     KSNTIVAATVIIFRFGSVLLGIITFVYILYANSFLMTMRQKDYAMFMMLGAKGRKIAQ
                     MIFSETFLVGIAATLVGSAVGVGLTSIVHRLLVDQLDLNISHFTPFSIHGLLITVLFF
                     AVLFLLAAVVNAFSIVKKPILALIRADQTPTRIKQHKFLFFLEVVLGIAFLGCGYYMM
                     KHVGTYQVFGIGVALVTIVLGTYFIFHSVIIFFLSLLKKSEQISLKKLNNFTLSQLNF
                     RIREYTQMLSMVAMLFALALGALTVGLGFKNEIADLTENNSGYDLVMNNPRAEDQQKI
                     KELSPTLSASYTQKEDAGTIYYNASEFAAQPLIMIKHEDGTPPKITKEKVPAKKMNEL
                     TVQEELRSYELPEQQEKEIKVVSQSEFDQLNLPQSTLQLVQVKDFQANLKPIETLVAQ
                     NKMNNPSLQKVEYSNQKYEMYEVYNGLFSGFEFMGFFLGLAFLTMLASCLMFKILSGS
                     KSDIARYEMLEKIGTRRGLLKQSIRREVGVLFLAPGILGVVHVLFGLQMFGLFMQNPY
                     KDIWVPFTIFFVLYFIYYVLTTWLYTGIVLKKRL"
     gene            16971..18011
                     /locus_tag="LLC22_001084"
     CDS             16971..18011
                     /locus_tag="LLC22_001084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337350.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose mutarotase"
                     /protein_id="HBK5434377.1"
                     /translation="MEINEQNFGENYHLITITNQNGTSLSVSDLGARVVHFQTIIDNE
                     KRELILGFDEAKEYLEKDPYIGASIGRMAGRITNGTFKLDDETFEVKTDPDTGHCLHG
                     GAPSFEAKQWHYTVINGENEASVIFYQTSPDMENGFPGTLDVEVRYTLTNDDTWRVTV
                     QGISDRKTVFNPTNHVYFNLTGDPAQSIDEHILWLNSRLFATLNKDTTPTGEVVSVSG
                     TAFDFQRPKKLGEVFASDFRQSMIVGGIDHPFLLKKQSGLLNAAELTSPDEKVSIQVK
                     TDASGIVIFTANFGEDGPEMRGNKLVNHGGITFETQELPGAERLESFGDVTLEPNQVR
                     EFVTEYKINIKK"
     gene            complement(18063..20207)
                     /locus_tag="LLC22_001085"
     CDS             complement(18063..20207)
                     /locus_tag="LLC22_001085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286297.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C40 family peptidase"
                     /protein_id="HBK5434378.1"
                     /translation="MKNKKTIRLLAATWLIAPSVLSTNTVFAVDNQIADQTVTTDTTT
                     SSSATSETTDSFTEDPTGTTNSTTGSTEPTEIDPADPSENEKPAETYSLTIAPSLIGK
                     IQLTASTADSPEQQPLDITESGTVEGLLAETKVTYTITPAEGEQIASVAVNGAKEVNY
                     DAKTFTVGTNNLSITAEFKAGPDTSTEKPTDPSEEVPSTPDPETPNKPDVGNNNNNNG
                     SNNSNNNNNNSNSGNSSNQTNPSGSNNNGNTQREPNHPNNGSSNGGTNNASSRPNTAN
                     QSGIENPSSASSDFVVKSPIDAVLPTNTTNVQQAIVREAFKHLGKPYVWGAKGPNTFD
                     CSGLTYYVYMKATGHYIGGWTGEQQYAGTQIPVSQAQPGDLVFWGPSSGVTHHVGIYI
                     GNGQFIHAPQPGDKVRVTSISDFTPDFAVRVNLAGLPAASGSLTGGSSILDGLDGSFH
                     FSQNQTTDQFLKKIADDAQEIGQKEGIYASVMMAQAILESGSGNSLLSSEPNHNLFGI
                     KGSYKGSSVTFNTLEQDSSGQSYQIRAQFRKYPSYKESLEDYADLIKNGLTGNPDFYK
                     PTWKSETKDYKEATKYLEGRYATDRQYSQKLNAIIEAYDLTKYDEPKKEAATTEEANA
                     EILNMSKRFDVPIKWTTDGVPITGLEFSTIKRVNNASSIFRVASIWDLWNNFTARQIP
                     ETTTRTVKAATVPVLTLLSLDKSFWLDLPLKK"
     gene            complement(20564..21937)
                     /locus_tag="LLC22_001086"
     CDS             complement(20564..21937)
                     /locus_tag="LLC22_001086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373274.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5434379.1"
                     /translation="METTMNPEQMVLSEQIHMLIEQLGGKDNIDSVLPCATRLRIKLK
                     KQPVANAEKLKQQIPSIKYFILLDRYAEIIMDQGLAPAYKELTRQIDHSAPKEKLNPI
                     EKLFGLISEIFTPIIPLFAGSGILKGLVVLATTIGWLSETSGTYHILSAASNAVFYFL
                     PIFLAFSAAKTFKVNGYIAAVIAAALIEPNLTSLLSDSGKAATDFLGIPVVLMQYTST
                     VMPAILGIFFYSFVEKFLKKYIRENMQLVFVPLLSLVITVPLTLMVFGPAGVYLGEGL
                     AAAITWMMDINGPISGAIIAGGWNILVIFGIQWAVNPVMISNISAYGFDRIVPLTGAA
                     NFGMAGAALGVFLRSKRSKTRSISGSAFASILLAGVTEPTVYGIAIPLKKPFVAACIG
                     AAAGGAVMGFAQVKAIAFVFGSLTTLPAFISGTFFWYLAGLAVSLVVAMITTLVSGFD
                     EDLMSYE"
     gene            complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LLC22_001087"
     CDS             complement(21937..22332)
                     /gene="rbsD"
                     /locus_tag="LLC22_001087"
                     /EC_number="5.4.99.62"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-ribose pyranase"
                     /protein_id="HBK5434380.1"
                     /translation="MKKGKVINSDISRVIAQMGHFDKLSIGDAGMPVPFGTEKIDLAV
                     SNGLPSFLSVLENVLEELEVQSIELAEEIKTMNPEILEKIKLLLPDTPISFIPHEEMK
                     KELNNCHAFIRTGEMTPYANIILVSGVVF"
     gene            complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LLC22_001088"
     CDS             complement(22360..23277)
                     /gene="rbsK"
                     /locus_tag="LLC22_001088"
                     /EC_number="2.7.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307932.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribokinase"
                     /protein_id="HBK5434381.1"
                     /translation="MNTVTVIGSINMDTTLRLTNMPKPGETMHAHEIFHAGGGKGANQ
                     AVAAKRSGARTSFIGGVGADSEGQQLLDLLTKENIDTSGIAEIQGATTGQAMIMVDAA
                     GENSILIHAGANNAFHEQEVLKNKQLITNSDFIIAQFESSLDATILAFSIAKDAGKTT
                     ILNPAPARETIPTELLEKTDIIIPNETETEIITGIRVTDHNSLVAAAEKLHELGIGTV
                     IITLGSAGAFYHTEKEHGIVPAFKVDAVDTTAAGDTFIGALSSTLQPDLSNLKEAILY
                     GNLASSVAVQSYGAQPSIPYREALEQSAV"
     gene            complement(23385..24398)
                     /locus_tag="LLC22_001089"
     CDS             complement(23385..24398)
                     /locus_tag="LLC22_001089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="substrate-binding domain-containing protein"
                     /protein_id="HBK5434382.1"
                     /translation="MVKKKITIKEVAKLSGVSITTVSLILNGNTEKFSPKTVQKVLAA
                     KEELGYQPDYFARQMITKETKTIGVLVPDITNPFFSTLMRGIEDILYKQNFVTILCNA
                     DSDHQKEIEYLAELTRRGVDGFIIATSAVSTDAINENLKKQGRPFIVLDQKKSEGFSD
                     AVRTDDFRGGYLAGMHLLSLGHQTIALVYPENPPENVHARIEGFKSALDVYQIPHDQL
                     ILLPTQFSKQGGYQITAELLDSAATGVFALNDELAFGLYRGLEEAGKSIPEDYSIIGY
                     DNIDMCEYIKPKLTTIAQPIFELGQTSAKLLLDRIQFPEKEWEEKRLPVRLEKRFSTA
                     PLK"
     gene            complement(24479..25078)
                     /locus_tag="LLC22_001090"
     CDS             complement(24479..25078)
                     /locus_tag="LLC22_001090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5434383.1"
                     /translation="MNDLKENMIFDLSKTAFVAIDMQKEIVNNGTLSPHTAASILTNN
                     DLLVRTLKRTAALKVLVNVDISTFPYLSQQTDMGGMTASVPPEFTDLLLKDSLKDTDN
                     MLTITKYNPSAFFGTSLDLQLRRRGIETIILSGVATTNGVYATALDAFQHGYHIVLAE
                     DACSDRDKESHQLFIKKIFPKTARVRSTKQIIEAIQQSK"
     gene            25264..25965
                     /locus_tag="LLC22_001091"
     CDS             25264..25965
                     /locus_tag="LLC22_001091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434384.1"
                     /translation="MKYVEVKNEYKRYKMGETTITANDDISFSIEKGELVIILGPSGA
                     GKSTILNILGGMDTPDEGQIIIDDTDIAQFSDKQLTAYRRTDVGFVFQFYNLVPNLTA
                     KENVELATEVSPDALDPVEVLRQVGLAHRLNNFPSQLSGGEQQRVSIARALAKNPKLL
                     LCDEPTGALDFETGKQVLKLLQNASRQHGNTVLIITHNSALAPIADRVIHINDAKVRS
                     VELNDHPSSIDEIVW"
     gene            25975..28686
                     /locus_tag="LLC22_001092"
     CDS             25975..28686
                     /locus_tag="LLC22_001092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434385.1"
                     /translation="MKTRTYLKAGFREIRQSKGRFIAIILIVMLGTLLFVGVKTAGPV
                     MQKTMDHYVGTAGLSDLQIVSTGGLTQKDIAQAEKIPDAKVETGKQIYYSNTGKNEVI
                     QIFSYNKNNKQNKLQLTDGKLPEKPNQLVLDEKAEDEGYKIGDIYQIDSDELKEKEYT
                     ITGFVRSPLFINNLERGYANVGNGSVDYFVYLPESVFKTDIYSVLYLDFTNVKNLNTY
                     SKAYKDKMEQNQEKAEKYLQDRPEERLEELKKSANEELEPAQQKIADGKAQTTQARTR
                     LEDAKKQLAQQSATIQQLPEAQRTIAVQTLSQQEAQLAEQERQLVEKERELASAEEEL
                     NRNAEKIENLTKPSYLYNERSENVGFQEFGDLSDRIAAIANVFPVFFFFIAALITFTT
                     MTRMVEENRREIGTLKALGYTKVEIAKKYAIYASLASGIGIVLGTILGTNLLPRIIFE
                     LSNERYDIGSALIFYDWPPILQAAAAFFIAAFGAAMIVLFKDLRERPAALLQPKAPKP
                     GKRIFLEYITPLWSRLSFNQKISYRNLFRYKSRMLMAIIGIAGCAGLMVAGVGLKDSL
                     SSVSAKQFGTIIDYQAIVTLDSSTEDSRQKAADMLQKQEKVNEILAIHTQTVELRKKG
                     HASQSLTVIVPSKTADLDRFIHLTDLEENPRSLPKTGIAITQKVAELFDLSTGDHISL
                     YDEDQKEWKVEVKEIVKNYLGSFIYMSPEYYASVTDQSMMDNAFLLRTDKMTTKEEEM
                     LSEKLLATDAVTNTSFMSKQIETQEESMANLDSVVLIFVVLSGLLAFIVLYNLTNINI
                     SERVRELSTIKVLGFFDKEVTMYIVRENIIFTLLGIIGGFGVGYILTDFILQQASMEN
                     VIFPLVITWWAYVLSAGLTIVFTVIVMIVTHFKLKHIDMIDALKSNE"
     gene            29137..30765
                     /gene="treC"
                     /locus_tag="LLC22_001093"
     CDS             29137..30765
                     /gene="treC"
                     /locus_tag="LLC22_001093"
                     /EC_number="3.2.1.93"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha,alpha-phosphotrehalase"
                     /protein_id="HBK5434386.1"
                     /translation="MTFKDKVIYQIYPKSYKDSNGDGIGDLKGIKEKLPYLNDLGIDM
                     IWLNPIYPSPQKDNGYDISDYTAIDPIFGTMEEFEQLIAEAKKYRIEIMLDMVLNHVS
                     TEHEWFKKALAGDQHYQDFFILREEPTDWVSKFGGSAWSPFGDTGKYYLHLYDRTQAD
                     LNWRNQAVREELFKVVRFWMEKGVKGFRFDVINVIGKDEQLKNNKENDGKPEYTDKPI
                     THTYLKELNQATFGTDSTIITVGEMSSTTIENCILYTEPSREELSMVFNFHHLKVDYE
                     NGNKWSTPPFDFAELKRLFHTWGEKMSEGNGWNALFFNNHDQPRALNRFVAIDQYRKQ
                     GAEMLATMIHLNRGTPYIYMGEEIGMIDPDYSSISDYIDVESLNAYKLLLEQGFTEKE
                     AFRRIKAKSRDNSRTPMQWSDTEQAGFTTGKPWLKVGGKLEEINVEKELSSEDSILSY
                     YKKLIRLRKTYPIVAQGDYHAYEANHPEVYGFLRQFEGQQLLVLTNFYDKDTRIAIPE
                     GFTEANILIDNYSDTVLHQSLELKPYQAIALLKN"
     gene            complement(30825..32006)
                     /locus_tag="LLC22_001094"
     CDS             complement(30825..32006)
                     /locus_tag="LLC22_001094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5434387.1"
                     /translation="MKKETDTTNRLIRFLGGKTSYYVLGIVILLALIIYFFHQISFIF
                     KPVGIIIATILPPLLFALILYYLLEPVIKRLSKHLSRNLSVIIVYVIILFLLGLGSIW
                     LIPFLEEQAKTLISSLPDLFQDFQESLRQFLEKTPFADSFNQFFASIDDVTSDIAGFI
                     GNYWESGAQRISNIFSTVTAIFITLFTGPIVAFFLLRDPQKFYQSVLAIVPPAFRTDF
                     KNLTKIANQQLGSFLKGQIIASFILGAVYWVCFLLIGLEFASVLAISAGLLCIIPYIG
                     PFIAFFPGLIIAFQDSTFMAVKFVIVWFAVQLLHGDLVIPRVMGDRLQIHPITILIVL
                     LVMGDLMGIVGVIFGIPIYTLVKLLVTFIFRKFKQRYNKFYGDKGEYENSSFSEEDYF
                     K"
     gene            32258..33781
                     /locus_tag="LLC22_001095"
     CDS             32258..33781
                     /locus_tag="LLC22_001095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000724057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBK5434388.1"
                     /translation="MKRLIGILAMLVLAGMLTACGASGKAEDSKEKLSVMTTFYPMYD
                     FTKAIVGDEGEVELLIPAGTDSHDYEPSAKDMAKIQDTDIFVYNDENMETWVPAIQKT
                     LQEGNVHTIKATEGMLLLPGSEEGHDHDHEHGEEGHTHELDPHVWLAPSLAIKQVANI
                     RDQLIEAYPEKQEVWTKNAAAYTEKLQALHQLYQETFKQAKQRSFVTQHAAFNYLALE
                     YGLNQVSIAGLSSSEEPSAARIAELKHFVKEHGINYIYFEENAKDSIARTLANEAGVS
                     LEVLNPLEGLTNEQIENGENYLSIMEANLEALKKTTETENPLEDTLTPKKEKSVYNGY
                     FEDEDVQDRSLSDWAGTWQTVDTYVEDGTFDPVFEYKEKLNQDKTAQEYKEYYTKGYQ
                     TDIASIKISEKEMAFTFKNGTTKRSNYRYVGKEILTYEAGNRGVRYLFEAEDKESGAF
                     RYIQFSDHTIAPADSEHFHLYAGNESQEVLLKEMENWPTFYPDTMDGREIAQEMLLH"
     gene            complement(33850..34578)
                     /locus_tag="LLC22_001096"
     CDS             complement(33850..34578)
                     /locus_tag="LLC22_001096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5434389.1"
                     /translation="MIPIYICEDDPKQLEVLSTVIKNRIMIENLDSYVHISTSDPEEL
                     LNAAKIRTSSFGIYFLDIELEDSEMDGVAIGKLIRELDPLGKIIYVTSHTEMSMKILK
                     SNIEPTDYIVKEDLYDLKENVEHILSKIFEDFQMSQIQKDIFKIEFNDEIKFLPIKDI
                     QYFSTSLGAPHKLEVHLTHAQLQFYEKIKEIEKMHRNFIRCHKSYVINTQNVRSINKK
                     TREVTLANGETIPASIRGLKKLIS"
     gene            complement(34591..35871)
                     /locus_tag="LLC22_001097"
     CDS             complement(34591..35871)
                     /locus_tag="LLC22_001097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK5434390.1"
                     /translation="MFLWSIALQYLIYTICILLIDHHIRYKYLFAGVILISCILIGWV
                     YSILGIFTALIAIGMLMLTFFFFSTSRQQLVYALPFGLLTSLLGDHLTSIGDFFVLKS
                     SVIEPGDSLQYFHIVLSAFLSALLAFCLKKSLETWFHTVDRRMIGTIGTLILFTYYII
                     IFYTRFSGETPDVLALNTSFFILYLCVGLIILVYYWKISNKKLADQLLEQQVRMQQDY
                     IKDLEKNYQDLREFKHDYQNLLFSLHSYISEGDLEGLRSYYDQTILPTRQMMNLFPAN
                     LSMLDNMKVPEIRSLLSLKLMMAQEKGLIVQLHFPEPIELDTKHTVNLVRMLGIILDN
                     AIEGASAAKKKKIELTILKKNHSVMIRVINTTTNTLPLNQLKQKGFSTKTNPKNEGLG
                     LFILDELTKTNPYLFLETSIENQRFSQTIYIQIK"
     gene            complement(36012..36614)
                     /locus_tag="LLC22_001098"
     CDS             complement(36012..36614)
                     /locus_tag="LLC22_001098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBK5434391.1"
                     /translation="MKDKVVNKLLEALFSGDKSEEDMVYVQVKFVLEVLLNNLGKLAV
                     VLVFSLVTGSWAETGITFLSYICIRRYAYGLHSDSEFVCLLWTLLYLWGVPLVMKHLQ
                     LTISFPMMVFLLISCFLLLLRYGSRGTAINPIEPEKRPPLLKKAISMFLIFSLITLFF
                     SASYFSTYLLLGIVLEIATLLPITNYLMNFGGIFHEKNNH"
     gene            36859..37065
                     /locus_tag="LLC22_001099"
     CDS             36859..37065
                     /locus_tag="LLC22_001099"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434392.1"
                     /translation="MENEQLFEVGETYAFKSDLFESPIKGKIEKIYENSVMIRVMKCA
                     VEDNDTAHNLHWQLVVRKSSTIEE"
     gene            37377..38096
                     /locus_tag="LLC22_001100"
     CDS             37377..38096
                     /locus_tag="LLC22_001100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBK5434393.1"
                     /translation="MPIIVIIVAGTIGAGKSTLTEMLAQDLETKPFYENVEDNEVLPL
                     FYSNPEKYTFLLQIFFLNKRFLAIKDAFSHDDNVLDRSIYEDSMLFHLNADLGRVSEV
                     EVKQYEGLLETMLKELEEISPQKKPDLLVYIRVSFETMLARIKKRGREYEQLEQDPEL
                     YSYYKELNRRYEEWYEQFDICPKIVIDGDKYDFVADPACGEQIVQEIKMRAKKMTEEA
                     DAQSIRYTTNNPKAKGIFTTK"
     gene            complement(38177..38860)
                     /locus_tag="LLC22_001101"
     CDS             complement(38177..38860)
                     /locus_tag="LLC22_001101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1275 domain-containing protein"
                     /protein_id="HBK5434394.1"
                     /translation="MQTSFHEGRTIGLLLTFIGGAMDSYTYIQYGAFASAQTGNIILS
                     IIQAFDGEWLSVGKKVLSTLFFFLGILLTKYLIDYFRKKEKHFWRLFVLYYEAVIFFF
                     VSLTPVHEHPALVTILIAFTASIQWVAFDKINGRAYTNLFTTGNLKGVATNLYDYCIS
                     KEKADFDRFFHYLSVVLAFIAGAIVLVFCHHLFGAHSILIVSILFLIMALTQTFHLWQ
                     FYHTNRFTI"
     gene            39078..41264
                     /locus_tag="LLC22_001102"
     CDS             39078..41264
                     /locus_tag="LLC22_001102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK5434395.1"
                     /translation="MNEKEILRLQKELKRWENKYKKLQQVFRLQEEIIATYEAAYGEA
                     PGLIEEEVQVKESEGNSSFFKMMEKRSYNRFNQEQKAAITYDMKKHLRIIAGAGSGKT
                     QTICAKAVYLMTQKQVDEERILMITFTRNAANELKKRVDNFSQRKTAVHIGTFHSIFF
                     RIYNEICRKFPEVAMQGIQGDFSKDTAQKVNAVLQQLIRKYNLYIFDQYGEKTIASRL
                     DYWQNMNLSVEEMVQLVKEKYDSIDKNARQPISERLYGLLTELQEQKRSQQLLEFNDV
                     LQNLKSALENEEIQHYIGQKYDYLFIDEFQDTNPLQWEIVKRMTKENRIKLIVVGDDD
                     QSIYGFRGSEPAYIKNFEKEYPTKTLFLLTNYRSRAAIVQGANRLISYNKNDRIPKAM
                     IPAQKEAGVMEAYLFSDTKAESQWLIKQIQTFIQKNGKYKESIILYRSASQTQQLVQS
                     LLKTNIPFVLEADSPYEGIFGIKSFQHFYQKIVHWQTALNLQKKNQAYQQLLRQLMAD
                     CYLKKSECDQYFSPKYQNISVADYILSISPNLKSKSAEIREFEEALRKTDQHQEIYSL
                     VQSYLHLPRIAKEIDQSDQEWIREEVKQHATFRRLQALSQETQATAKELKTRLIAYRQ
                     GKLDALCIQSIHKSKGLSYRNVFLIGCNEGSLPYNGATEKKVIDFNEIKAEPVTTIEE
                     ERRLFYVAMTRARNRLYLCVPQMKNSRKLKVSRFIKETGSRVKKGK"
BASE COUNT        13384 a         7322 c         8275 g        12285 t
ORIGIN      
        1 aggaagaggt tgtgagcctg ccgtttaact ctgagtcaca aggagcaatt tcaaaaaaca
       61 gcttctcatg tttgttgact attgtgactt gtgaccgagg agttggcagg agaacaccgt
      121 ttattcgaaa aaaggaactg cgacaagact tttgtcacag ttccttcttt tttttgctat
      181 gctatactag atgtaaaaaa taggagaaat aaaatgaggg aaatttattc ttttgaatca
      241 aaaatctatg cttccgaagt cggcaagggc ggggcatata ttatttttcc gtatgatata
      301 agaaaagaat tcggtgctgg aagagttaaa gtccaagcaa cttttgacaa tgtgccatat
      361 gaaggcagta tcgtgaatat gggcgtgaaa aatccagatg gttcagtctg ctacatcctt
      421 ggactacgaa aagatattcg taaaaacatc ggaaaagaaa tcggtgatat tgtagcagtt
      481 acagtgaagc aaaaataaaa gaggttgtga caaaagacgt gtcacaacct cttgataaac
      541 ggtgttcaaa agccagtttc tcggtagtaa gtcaaattta tgcaaaaatg tggaaaccca
      601 tgtttacaaa atttttctta ctactcgaaa cgaagcggct ttatcacaac ctcttgataa
      661 acggcgttca atcagctgtc cctcggtatt agctcaaaaa cggcaaaata tgagaagcta
      721 tttttccatt tttttctctc atactcaggt cataacgctg atttcacaac ctcttctttc
      781 ataatggttt ttcaccatct ttataataaa ctggttcttt gatatggaaa tctatttttt
      841 ccaaccaatc taaaatcttg taacctaact cttctgacat cggaaaagag gcgttgattt
      901 gtgcattgga gatatggtca acatggatac cggaagtgat cgtacaactt cccggaacgg
      961 cagttttgat gatcacagct attttttcgg ctaagacatc gtctttatgg aaccgaccat
     1021 cgtggctagg gaaacgtaca gtttgcatct ctgtatcacg agaaaatgta gtgactgttc
     1081 cgatatgtgg tgtatctccg cctgttaaag tgatcaataa gtctttaccg attactttaa
     1141 cagcagcttg gatcgtgaaa cctagtttgg ttacttcaac tatcgtttct ttttccatat
     1201 taatcaccct gccaacgttt tgaatgctca tttacaattt caaattgatc caaaagtttc
     1261 attgtatggt gattaacaag atcttggatc gtttgaggct gattataaaa agcaggaatt
     1321 ggtggtatga tttgcacacc tagtcgtgct aatttagtca agttttccaa gtgaatggca
     1381 tttaatggcg tttcacgagg aacaatgact aactttcgtt gctccttcat tgttacatca
     1441 gcagcacgtg caatcaggtt gtcgcctaaa ccaacagaga tacctgcgac tgttttcatg
     1501 cttgccggta cgatgatcat tccatcggtc aaaaatgatc cgctggcgac agcagcacct
     1561 aaatctttgt ttgaataatg gtaatcaaac aggctttcga attcagttag tgataagtcg
     1621 gattccagct ttaagttctg ttttgcccat ggactgatga ttccgtgtgt ttctatcatc
     1681 ggatattctt ttagtttctt cactaggttg atggcataaa tggtgcctga agcgccactt
     1741 acaccaatca cgattttttt cttccgttgt gccaattgtt ccattttccg cactcctttt
     1801 tatgatgtca aaacagttgc agatcattca ttatttcaaa tatttttccc aatcttctac
     1861 ttcttggaat tttgcacgta caaaatgttc tttcatatcg aaaggaactg taccgtcaaa
     1921 gatagttttt gcacttatcc cacggaaacg aatagagcca ggattatatt ctggtaattc
     1981 tgatgggtcc aatggatggt tcctcattcc tgggatcacg atgatatctt tatctccttg
     2041 gaaacgagtg ttgaaagtcc aaactacatc gttcatgtcg aaaatatcaa catcttcatc
     2101 gactaaaatg actgtcttca attctttgaa ggctgataaa gcaagaatag ctgcttgacg
     2161 ctgaatacct tcatccgctt cgttttcttt acggatttgc atgatggtca tcaatttacc
     2221 accacctgca ggaggattgt agacatttac tacttttcct ggaatagctt tatcgaccaa
     2281 ggcaagaata cttgcttctg taggaatacc ggccatagat acgtgttctt cactgggacc
     2341 aatcgttgtt tgcatgattg gattgtcttt tcggtgagta actgctttga ctttcactac
     2401 ttgtacagct ggattagcat ccccagtata gccaggaaat tctggcattg cttttcctga
     2461 gttcgtgttg atatcttctt gcattgtttc atttggcatg atttctgctt caatgatgaa
     2521 ttcagcacga gcaataccca cttcatcgac tgctatacca tcaacgattt gaataggttc
     2581 gttacgcaaa gctcctgcac accatagttc attgtagcca agtggagtgg taggtggttc
     2641 gaaagtcgtg ccaatggcaa ttgctggatc taaaccaata ttgatagtga taggcattgg
     2701 tttattcaag gcttcgaatt gtttttggaa gtgaccaatg tggcgtccgc caggcatgat
     2761 gtacataccg atcgtatctt tatcttctag aaccatacga tggatcgtta catcgctcat
     2821 tgttttttct ggatctgatc ctaagactac acccattgtg atgtatggac cagcatcttc
     2881 aggagtattt gtaggtgcag gcaaaatgtt gcgaatatcg aagtctgcat cggtagctag
     2941 atgaacgact tcttgtgctg gagcgtctgc tttgtctact ttcacaggtt tgattggatt
     3001 ttctacagcg tctttcaaga aacgaccaag tgttcgataa tcatggtgca aaatttcacc
     3061 tacacgttta cgactagcca ttgttccgat gttcacacgt gtgccgggga aacctttgat
     3121 attgttgaaa gtcatagttg gtccttcttg agtcggacgt tttactgtac cgccagcacc
     3181 gatataacgg taaacaccag ataattctgc ttcaggatcg atttcaatat ctgtttcgtg
     3241 atattgacct ggaagtgttt ttagttcttc gatgactttt cttaaatcat acggttgatc
     3301 tgtcatgaga gattcctcct tagttgtctt tacctatcta tagtaaaagg tgaaaaagag
     3361 gaaaacaatt caacttgttc ggtaaagtat tctacaatgg aatggatgcg tttttttgat
     3421 aatagaataa actatgatat acttatcact aaaagaaagc gcatacttag tgttggagga
     3481 aggaaagtga aaaaaatgga ggagtcattt cctaaagcag taaaagtgga aaatatagcg
     3541 aatattttga aagttacatt tgaaaacgga gaagtaaaat acgtgaaatc tcattggaca
     3601 gaagagataa ccgatgcctt gcaatttgga aaaaaaggaa gaggaaaaag aaaaaatctt
     3661 ctcgcacttt ctcgtaatat gtggattggg actgaagtaa cgattgaagc agatggaaca
     3721 gtattcataa atggaaaaga caggtatacg ccagaagagt tgtggtacaa aggaaagaaa
     3781 agtataccag aattataaaa aataattaaa aaaaacagcg cgaaacaagg aacatattac
     3841 ttcctcgttt cttgctgttt tctactattt cagcgctctt atgactcaaa tctaaatgtg
     3901 gttgtcacaa ccttattctg cacgcaaagc gatagcggcg tcttttttcg ctgccattcg
     3961 tgcaggaaga tgaccgccaa gcatcgtcaa tatagtagag acgatcacta gaataatcgc
     4021 atggacagga tttagttgag caacattttt tagatccgtc atgttgtata agatgctatt
     4081 gatagggaac gtagctagcc atgcaataaa cacacctaat atcccagaag aaatacctaa
     4141 aatacacgtt tctgcgtcaa atacgcgagt gatgtctttt ttacgtgcac ctaaagcttt
     4201 tagtacaccg atttcttttg tccgttcaat cacagatgta taagtaatga tactgatcat
     4261 gatcatactt gttactaaag agatccctgc aaaagcaata aggacataag tgatagcatc
     4321 catcaatccg ccagtcagtt cagtcatcgt tccagctaaa tcagtataaa tgattttatc
     4381 ttcatctgat ttgcctttat tgtaatcatc tagataatcc aagatctttt ctttgtcttc
     4441 aaaattgttc ggataaatca tgatacttga aggcaagctg tctccaccta aataactaag
     4501 caatgtttgt ttggcatttt cgtcaacttt ttcagtagtt aagacattta caccactgtc
     4561 tctttgagct ttgacgattt ctgattcttt gttttcgttg acgatttgag tcgttaattg
     4621 atcgctataa gcgattcctg gagataagag attcattgta gaagaagatt tcacgcgtag
     4681 gatccccgag atcttcaatt catcagaagc attctgatac atcgcatcat aatctgtatt
     4741 agggataaaa ttcccagttg gaagttttgt atagtaagta ttgttgttta ctaatttgaa
     4801 tgttgtacca acgatatcat caaaatcaag tttttcgtct tctttcacat caaatccaag
     4861 attcttcaat gcgttgatat tagtattatt attgccgtct acgatcagca cgacatctgt
     4921 tgctgaggct ggataacttc cggcaagtaa agaataattg tcttttaaaa agttttcttt
     4981 gctagtgtca agctgtgtag ggaaacttga cactcccaca cctgtcattg ctgacatcgt
     5041 actagataaa gaaagagatt ccgtatcagg attttgattc gagaagctga caggctgtac
     5101 tttgccattt acatcacgta aaagattgat tcctgtagta cgggtaaatc cgatattatt
     5161 acttaagtta ggatcgatgt ctgttacgta atcgacgtat gtttgatcaa tcttattcgt
     5221 gtgctgtgct ttatcttctt cgctgacttt tgcagtaatc gttttgctgt ctggataatc
     5281 cgctttgctt gcacccaatc cggcatcgtc acgagtctgg ttagtcgtta ccttagaaat
     5341 agtaatcgga aatttcgcca tcgtttcagc ttgcgtgtta tcgatttgtt tttggaatcc
     5401 agaagaaagg gacagaacga tcgcgattcc gatgatccca atactggaag caaaggaggt
     5461 caagaaagta cgtccttttt ttgttcggat attgttgaag gaaagcttta acgctgtcca
     5521 aaaactcatc tttgttctgc gtaagttaaa ttgatcatct tttggtcgtt cgatgtgagg
     5581 atgggaatct gttaagatct taccatcaga aaattcaatg attcgatctg cgtattgatg
     5641 ggccagttca ggattatgtg tgaccatgat cactaatttt tctttcgata actcttggat
     5701 caattccatg atctggatac ttgtttctgt atctaacgct ccggttggtt catcgcacaa
     5761 aaggatatct gggtcattgg ctagtgctcg agcgatggcc actcgctgca tttgtccacc
     5821 agataactga tttggctttt tatgcatatg atttgtcaag ccgactcggt gcaatgcatc
     5881 ttctgcccgt tttcgttttt cgtctttaga aacaccactt aatgtcatcc caagttcaac
     5941 gttttcaata atgcctagat gaccaatcaa gttgtaactt tgaaaaatga aaccgataga
     6001 gttgtttcgg taggcatccc agtcactgtc cttaaagtct ttagtagact ttccgttgat
     6061 taccatatca ccggaatcat aattatctag tccaccaatc acattcagca tagtcgtttt
     6121 accagaacca ctaggaccta aaatcgctac gaattctttt tgtctgaaag cgacagacac
     6181 accatccaat gctttggtgg tggtttcgcc gactttataa tattttttta tatcttttaa
     6241 ttgaagcata atcacccttc tcccgtattg aaatattcgg tatactaata agtatatcag
     6301 aacaatgatc gtagtatacg aaataaatgt taactgaaga tgaactacaa gaaaaaatct
     6361 agaaattttt caaaaaacag agggagatca atgaatcgta ttttagtagt agaagatgat
     6421 ccgcaattac agttgcttta ccgttctgtg ttggaacgag cgggcttttc agtcatcacc
     6481 gcattgaatg gagaggatgc gctgaaaaaa ctagaagcga cacgtataga attaatcatt
     6541 acagatatca tgatgccgaa aatggatggc tatgacttgc tagactcatt acgtagcacc
     6601 agatttgaca cacctgttct aatgattacg gcaaaggccg attttgagga taagaaacgc
     6661 gggttcaaat taggagcaga tgattatatg acaaaaccca tcgatgtcaa tgagatgatc
     6721 ctacgtgtgg aagcattgct tcgacgttca aagatcaatt acagcagtag cttgataatc
     6781 ggacaaacaa aattagagct agatgcttat acagtgttac aagatcagca ttcgttgatt
     6841 ctgcctcaaa aagaatttct gcttctgtat aaattactgt cttatcccaa caagatcttc
     6901 actcgccaac agttgatgga tgatatttgg ggattagata cgaatacaga agaacgaacg
     6961 atcgatgtac atatcaaacg tttaaggacc cgttttgaaa agacggaaga ttttcaaatc
     7021 atcacagtac ggggactagg ctataaggcg gttatttaaa gatgaaaaaa aagctatttt
     7081 cacaattatg gatctatttt gctagtattg tcttcatttc gatcttagtg acactgctgt
     7141 gttttctcgg ttttattttc ttattgtctc gacattctat ctcgcctgct gaatcggctg
     7201 gaaaaccaac gttatacccg ttattcgtct ttgcggggtt cagtatggtc gtgggtacag
     7261 gaatatcgat ttttgttggg cggcgtatcc tgcatccaat cagtgcgcta gggacaaata
     7321 tgagtctggt agcaacggga gatttttcga ttcgaatgga tgaacagcag aaagtagcag
     7381 aagtacagca actgtataaa gatttcaacg ttatggtcca agaactcaat agtatcgaga
     7441 cactgaggaa tgactttgtg tccagtgtat cccatgaatt caaaacacca ctagcaacaa
     7501 tccaaggata tgttcaattg ttacaagccc caaatctctc tgacgaagaa cgccaaatat
     7561 ttttatatcg gattatcgaa agtatcacgc agctttcaca attaacagag aacatcttaa
     7621 aattgaacaa actggaaaac cagcgtatcc aactggaaaa gaaagagtat cgattagatg
     7681 aacaaatcag agaagtaatc gttttttttc agcctaaatg ggagaaagaa cagctagaat
     7741 tggatatcga acttgctgca gtaaattaca caggcaatga agagtttttg taccaagtgt
     7801 ggctgaatat catggataac gccataaagt acaatcaaat caatggacag attcatatca
     7861 aactatttga gacagccaca gagattgtac tggaagtgac cgattcaggt gtaggaatga
     7921 atgaagagac cagagatcga atgtttgaaa aattttatca aggagataca agtcgtcaaa
     7981 tttctgggaa tgggctagga ctttcactgg ttaaaaaaat tctagaactg catgatggac
     8041 gtattgatta tagcagtatc gaaggagtag gaacgacagc aatgatacgg ttaagtaaac
     8101 aataggaaaa agaataaaac ccctaaaaat tctattgaag gtttttaggg gtttttagtc
     8161 gtttttttgt gattagggaa atgttcttac ggttcttttg gcataaaaat cgctgctttc
     8221 ttattgaact acgagaaatg ttagaggtgt cattgaaaca aggacatgat gcaagaaaga
     8281 gagcgaaagt catgcgtcgc tctctttttt tgggtggata gatggacaga aaatgtaggg
     8341 cttagttttc ttcttgattt aaatactccc aaaatgtatc tgaagccaaa gaatgctcac
     8401 cgactttacg agtaaatgca agataactct ctgttgttgg agaaataggg agaatcacag
     8461 tattttcttt taatagattc ttgactgttt tttccataac aatagcaatc cccatgtcat
     8521 ttgcaatcat attgatgatc aagtcgattc ttgctccttt ataagagatt tttggttcaa
     8581 atccagcttc gcgacacaga tctagtacag gttgatacaa gttcgtagtg gggccaagga
     8641 gcaaaaagtt ctcctttttc agttcgctta gatccaattt ctttttacta gctaaaggat
     8701 gatttttagg tagaactgct acaaaatcgt ctgtttcagt aggcaaccac tcaatcgaac
     8761 ttggtggggc ctggaaactt ctagcaaagt ggatcgtgtc actatgttca ttggcgtcat
     8821 tgtaagttaa ttcgacactt tccacttctt tcaactggac tgtaaattca ggatggcgtt
     8881 tcaaaaactc ggtgattttg gaaaaacctt tataattgat cattgtcggt atcgttaaga
     8941 tatttaatga aagattgttg tctttcgtat aggtttcaag cacttcttgc atagcatggt
     9001 attgttctac gacatttttt acatatggga gcaataagct tccagcttcg gtcaattcga
     9061 tttttctatg ggcgcgttcg aataatttga cgtctaattc tgtttctaac gaaagaatct
     9121 gtttagaaat atttccttgg gtggtgaatt gtcgatcagc agttttggtg aaattcattg
     9181 tttcggctaa atcaagaaaa acttcgaatt tatggatatc catcatattc ctcctactta
     9241 ttccaataaa gaatacttta acacaaaaaa tgaattggtg taatcttctc tgtctgttac
     9301 aatctttctt gcagcgaaag caataattac agaaattttt ctgatttttt tcgcttcgta
     9361 gaaaaagaga ggagtttttt gatgccaact ggagttttga tcaatgtagg ttccgttttg
     9421 tttggcggac taattggcgg attagtagga aataaattaa gtgaacattt taaagcacag
     9481 ctgacgatgg tttttggtgt gtgttcgatg gggatgggaa tctattccat tgcgccgatg
     9541 aaaaatatgc cggctgttat ttttgcttta gtgataggaa cagcgattgg tttgattgtt
     9601 catttaggta atgggataaa taagggggct gcgctgatgc aagtacctat ttctaaaatc
     9661 ttccctagtg aaaagcttgg tatgacccac gatgaattta tcagcacatt agtgacggtc
     9721 attgttctat tttgtgcaag tggtacgggg atctatggaa gtttagattc tgggatgaca
     9781 ggagacagta cgattttgat ttctaaatct gtccttgatt ttttcacagc agctattttt
     9841 gcgtgtaatt tagggtatgt cgtttctgtg atagcaattc cccaattcat tattttttat
     9901 attttgttct tattggcaaa atttatttat ccattgacta caccagacat gatcttagat
     9961 tttaaagctt gcggcggatt cttgatggtc gctaccggtt ttagaatgat caacgtgaaa
    10021 atgttcccag tagctgacat gatacctgca atgatcgtta tcatgccact gagctggatg
    10081 tggacaaatt ggattatgcc actgttataa taaaaatcaa agagaagcca ttttttgctg
    10141 actaaaaagg atcaaatctt ttagtcagtt tttttgtatt tgacaaactg attttgaaac
    10201 tatattatat gttgtataat atagattgaa ataaaatatt acacttgaga atagaaggtg
    10261 acgtaatgca catccagatt ccaactgttc ttcttgatgg tactgtgcta gcagcattaa
    10321 gcaaggaaga tatgtatggg tatgccttaa caaaaatcgt acaagaaagt ctctctgtca
    10381 gtgaatctac actatatccg gttttgagaa gattgaaaaa agaaggatat cttgagacct
    10441 atgatgaacc ttttgaaggc agaaaccgtc gatattactc gttgacacca atgggaagtc
    10501 gtcatttaga agaaattatt gatgaatgga ttgtttttcg agattcttta gaccggttat
    10561 tggaggagag cacaaatgaa tgaatatttg aatgaagttg tggatcatct tcaagaaatt
    10621 cctgaagacg atcgttttga tttgatccag tattatgagg aatatttttt agattctgga
    10681 aaaacattag atcagatcat tgatgaatat ggtacaccaa agcagtttgc cttaaaatta
    10741 aaaatcagtt acttttcaga agaagaacaa gcagaaaacg agttagtgaa aaatccaaaa
    10801 agacaaattc gcctggtttg gttaatcatt atcggtttat ttgcttctcc tgtcctcatt
    10861 ccactagcac tggggtttat attggttatt gggggactat tggttgcttt actagcgctc
    10921 atttttagta tctatgtttt atgtatcagt atcttaggtg ttggcctatt catgatcatc
    10981 tcaggaatca gtgtgtttgg acaatcgatt ctgagtggat tattctttat cggtgtcggt
    11041 ctgttcgcca caggaagcgc agtatttatt tcgccactgt tgctgaaagg aacaaaaggg
    11101 cttttttatg tcatgatgaa ctttgttaaa tggatgggac gacgttttat tacaaaaaga
    11161 gatctgcatt cagcgggcgt ttgaaggagg acacataaat tgagattgaa acattttttg
    11221 attaccggta ttggtctgat gcttactggt ggcctcctag caggtgcaac ttatacatta
    11281 ggcgctcaaa agagtctgac ttgggataat ggtcctcggt tgatcgatat ggttactgag
    11341 acaaaaaaaa tcaaggatgc aaacaaaatc gtcatccatg cagaaaatca aacagtttcg
    11401 gtcatacgcg gattggattt tgagataaaa acgacttatg ataagacaga aaagccagaa
    11461 ataaaggaga aaaatggcgt gttgactgtg aatgcagtca aaaaatcaac aggtgcaatc
    11521 attagtttag aagacacaag tgcacaaatc actattgttg tccctgcaga tcatgaatta
    11581 tctgaattga caatcgaagg gaataatagt gcaattgata tcaacgaagt atcaatcaaa
    11641 aaagtgaata ctaagacaca tgatggctgg gtatcgttca atgaatttac aggaggaaca
    11701 ataactgcga aagatgaatt aggctcactt cgattagatg aggccaatgt ggataacttg
    11761 atcgtcacag gtgaaaacag caacttccat ctagaagaca gtttgatcag caaagaagga
    11821 aaagtcatcc taaacggtgg caatttatct ttgcatgaga tggaaaacag tggctatact
    11881 atccaaacgt ctggtgaatc ttatattgaa aaagactacc agccaataac aaatactttg
    11941 ttagaacaag gacagaaaaa gctaaagatc actgctaaag acacatcgat caatattacg
    12001 acggatcaag aggacaatga aacagattga tcctgtactc aactggatat tttaagaaaa
    12061 aacagcaaag atccttccaa tctttgctgt ttttcatcgc ttaacgcaca taactatagt
    12121 aaaataagaa agaaaatatc taaaaagaaa acagggtgaa agagtatatg aaggtagaag
    12181 aaggtcaaag agaaaagtta aaaacagaaa tggaaagatt acatacttat atcactcaac
    12241 taagccaaac cttctatgat ccagacaaag aaaaagtgat ggttaattac ccgaacaatt
    12301 cagaaggtcg ccaattagag caagtgtacc atgaagtttt caaacattta ttgacggtga
    12361 agaaagagct ggattattat tctttaccga ttatcgatac aggaatattg aagtatgatg
    12421 ggaagaagga acgatttatc tttaaatctg ttcgggaaga tttgcctctt tcagcaggga
    12481 tggatctaga ggtcttggta gaagactatt ttacagaaga aaagcactgg gttcgaacaa
    12541 aattggatta tttaccgcag gcagccggag ggacacaggc aagcggttgg tacatcactg
    12601 aagacaaaga gttagaacta gaaggtgtaa tggcgcgtat tcgaaaaaaa aattaaaaaa
    12661 gtaacattag atatttattg aaggataaag gagcgcagga agtagcatga gagaaaaaag
    12721 agcattttat atcaatggtt atgcagggat tgtcggattg gtcgtattag ctttagttgg
    12781 attgtttttc ttctatttag gtatgtggca agcgaaagtt tgggcacttt ttttaagtat
    12841 ttttctttgg ttgatcacgt tattgttgtt aagttcggca actgtagtca gtcctaatca
    12901 agcaaaagta attttgtttt ttggacaata tttaggtacg attcgagaaa atggcttttt
    12961 ccttacgata cctttggcac aaaaaatgac tgtttcgttg aaagttcgga atttcaatag
    13021 ttctgtttta aaagtcaatg atttggatgg aaaccccatc gaaatctcag cagtagtagt
    13081 ctttaaagtc gttgatacag caaaggcatt attcgatgta gcgtattatc aagattttgt
    13141 agaaatccaa agtgagacag ccattcggca tatcgctagc caatacccgt atgatacatt
    13201 caatgagaat gatttgacgc ttcgaggaaa cacgacggca gtgtctgacg agttgcaaaa
    13261 agagctgcaa gagcgtttag cagtagcagg tgtcgaagta atcgaaacac gcttgaacca
    13321 tttagcctat gcaacagaaa tcgctagtgc catgctccaa cgtcaacaag caaaagccat
    13381 tttgtctgct cgacaaacca ttgttgaagg agctgtcaca atcactcaaa tggccttaga
    13441 gcaaatcgaa gatggacaag aaatcaattt caccgatgat cggaaagtcc aattgatcaa
    13501 taatttactt gtctcaatca ttacagacaa aggaacgcaa cctgttatca atacaggcga
    13561 catgaaagac cgtaagtgac atactttttg taagatagga agaaggagtt taggacggat
    13621 tattgtcttg aactcttttt ttagttgttt taaagaaaat gacaaaattg aaagaagaat
    13681 gatagttgat tcgaaggcag aattgttcgc ttttttctat aatcagtata taaagtaaga
    13741 gagaagggga aaaagtgaaa aaacttctga tcggtctact tgttttcatc gttgtggtac
    13801 ttgcaggggt gaaaatcgca gattacgtag ttatgggtgg agaagaatac tatgtacaaa
    13861 ttacgacaga tggtacaaaa acagtttcaa aatcagactc tggacaagaa acagtcaact
    13921 atagatatat cctgcctggc tatacgaaag agggtaagga aaaagaactg gacttcaagg
    13981 gacaattgac tcgaccgctt cgtaaaggag catatttaaa aatcacctgg aacaaaaata
    14041 aaggtgtcac ttcgtatgaa gaagtcgaaa aaaaagacgt gccgaaaaca gcactggaaa
    14101 aactaattaa agggtaggga aagaaatgaa caaaatagtc gaagtacaga atgtaacaaa
    14161 agtatacgga aaaaacaatg agaaaaagac gcaagcatta agcggcatca gcttcgatgt
    14221 agaaaaaggc gaatttattg ggatcatggg cgcttctggt tctggtaagt cgacactttt
    14281 gaatatttta tccacattag ataaaccaac agatgggcat atccgaatca atcaaaaaga
    14341 tgtgaccaca ttaaaaggaa atcaactagc agattttcgt gcgaatgaga ttggctttat
    14401 tttccaagat ttcaatttat tagaaagctt gacagcacaa gaaaatatcg ctgttcctct
    14461 ttctttacaa ggcgtcagac caaaagaaat caagcaacgt gtccaaaaaa ttgcagaacg
    14521 tttatccatc tctcatattt tggaaagcta tccttctgag atttccggtg gacaaaaaca
    14581 acgggtcgcc gccgcacgtg cattgatcac acaaccaacg attctattag gggatgagcc
    14641 tacaggtgcg ctggattcca aaagtgcccg ggatctttta gatacgatgg acgaattgaa
    14701 tacaaaagat catgtatcga ttcttcttgt gacgcatgat ccgttttctg caagttattg
    14761 ccaacgtatt ttattcatca aggatggcgg tatccatcaa gaagtgaaac gtggagatca
    14821 aagccgtgat tccttctatc gagaaatact atctattctt ggaaacttgg aacagtaggg
    14881 ggagattgac tatgctttgg aaattatcac ttactgggat caagagccgt ttaagagact
    14941 acttggtgtt attctcagga ttagttatgg catctgctat tttttacatg tttgaatcaa
    15001 tggcaagcaa cgaagctttt ttgaaaagta atacgatcgt tgcggctaca gttatcattt
    15061 tccgattcgg ttctgtttta ctagggatca tcacattcgt ttatatttta tatgcaaatt
    15121 cctttttgat gacgatgcgg caaaaagact atgcaatgtt tatgatgctg ggagcaaaag
    15181 gcagaaaaat cgcacagatg attttttctg aaacattctt agtagggatc gcagctactt
    15241 tagtgggttc agctgtcggt gtaggattga caagtatcgt ccaccgatta ttagtggatc
    15301 agttagatct caatatttcg cattttacac cttttagtat tcacgggttg ttgatcactg
    15361 ttttgttttt tgctgttttg tttttattag ctgctgttgt caatgctttt tcgattgtca
    15421 aaaaaccgat tttagcattg attcgtgcgg atcagacacc aacaagaatc aagcagcata
    15481 aattcttgtt tttccttgaa gtagtactgg gaattgcttt tctaggctgc ggttactata
    15541 tgatgaaaca cgtggggacc tatcaagtct ttggtatagg ggtagcctta gttacgatcg
    15601 tattaggaac ttatttcatt ttccattctg tgatcatttt ctttttatca ttactaaaga
    15661 aatcagaaca gatttcattg aaaaaattga acaatttcac attgtcacag ttaaactttc
    15721 gtattcgtga atatacacaa atgctctcaa tggtcgctat gctgtttgcc ttggcactgg
    15781 gcgctttgac ggtaggatta ggttttaaaa atgaaattgc agacttgaca gaaaacaatt
    15841 ctggatatga tctagtgatg aataatcctc gggcagaaga tcagcaaaaa atcaaagaac
    15901 tttcaccaac actttctgct tcttatactc aaaaagaaga tgcgggaacg atttactata
    15961 atgcaagtga atttgcggct caaccattga tcatgataaa acatgaagat ggaacaccgc
    16021 cgaagatcac gaaagaaaaa gttcctgcta aaaaaatgaa tgaactgact gtacaagagg
    16081 aacttcgaag ctatgaattg ccggaacagc aagaaaaaga aatcaaggta gtcagtcaat
    16141 cagaatttga tcaactgaac ttgccacaat ccactttaca gctagttcag gtaaaagact
    16201 tccaagcaaa cctgaaacca atcgaaacac ttgttgctca aaataaaatg aacaatccat
    16261 ctttgcaaaa agtagagtac agcaaccaga aatatgaaat gtatgaagtg tataatggtc
    16321 tattctctgg ttttgaattt atgggattct tcctaggttt agctttcttg accatgcttg
    16381 ctagctgttt gatgttcaag atcttgtcag gaagcaagag tgacattgct cgttatgaaa
    16441 tgcttgaaaa gataggaaca cgacgcgggt tgcttaaaca atcgatccgt agagaagtag
    16501 gcgtgttatt cttagcacca ggaatcttag gtgtagtcca tgtcttattc ggattacaaa
    16561 tgtttggtct attcatgcaa aatccataca aagatatttg ggttccgttt acgatattct
    16621 tcgtattgta tttcatctac tatgtactga cgacatggtt atatactgga atcgtattga
    16681 aaaagagatt gtgaaaaagc tgtcctgcat caagtaataa gaacagccaa gcaaaaatag
    16741 ctcctcatat ttttcgtttg gttgggctta ttaccgcaga tgcaagcttt tgaacaccgt
    16801 ttgttcggaa aaagaggttg tgacaatatt tttgtcacaa cctttttttc acggtctttt
    16861 attagaatat agtaaatttt ttctcgttac tcacggaata agctgttaag aaaacggttt
    16921 ccatgtatgc tggaatcagt gcaaatgaaa gaaaagaggg tgcaaggaac atggaaatca
    16981 atgaacaaaa ttttggcgaa aactatcact tgattacgat cacgaatcaa aatgggacat
    17041 ctttgtctgt cagtgatctt ggggcacggg ttgttcattt tcaaacaata atcgataatg
    17101 aaaaacgaga gttgatctta ggttttgatg aagcaaaaga atatctagaa aaagaccctt
    17161 atatcggtgc ttcaatcgga cgtatggctg gacggattac gaatggcaca ttcaaattag
    17221 atgatgaaac gttcgaagta aaaacagacc cggacactgg tcattgttta catggtggtg
    17281 cacctagctt tgaagccaag cagtggcatt atacagtcat caatggtgaa aacgaagcat
    17341 cggtcatttt ctatcagact agcccagata tggaaaacgg atttcctgga actttagatg
    17401 tagaagtacg gtatacgctg acgaacgatg atacatggcg agtgacggtc caagggatca
    17461 gtgaccgcaa aacagtattc aatcctacaa atcatgtcta tttcaattta accggtgatc
    17521 cagcacagtc aatcgacgaa catatacttt ggttgaatag ccgattattt gctacgctca
    17581 ataaagatac aacgcctaca ggagaagtag tttcagtaag tggcacagca tttgacttcc
    17641 aacgtcctaa aaaattaggt gaggtctttg ccagtgattt tcgccaatca atgatagtgg
    17701 gcggcatcga tcatccattt ttgttgaaaa aacaatctgg tttactaaat gctgcggaat
    17761 tgacaagccc agatgaaaaa gtatcgatcc aagtaaaaac agatgcttca ggaatcgtga
    17821 tttttacagc aaattttgga gaagatggac cggaaatgcg cgggaataaa ttagtaaatc
    17881 atggcggtat cacatttgag actcaagaac tgccaggagc ggagcgactt gaaagttttg
    17941 gagatgtcac tctggaacct aaccaagtac gcgagtttgt aacggaatac aaaataaata
    18001 taaagaaata gaataaatta aaaagggagt gtgacagtgt cacatcccct ttttaattta
    18061 ttctatttct ttaaaggcag atcaagccag aatgatttgt ctaaacttaa caaggttagt
    18121 acaggaacag ttgcagcttt aactgtacga gtagttgttt ctggtatctg tcttgccgta
    18181 aaattgttcc acaaatccca gattgaagcg acacggaaga tggaagaagc gttgttgacg
    18241 cgttttatcg ttgaaaattc taatcctgtg attggcacgc catctgttgt ccatttgatt
    18301 ggcacatcga atcgcttaga catattgagg atttcagcgt ttgcttcttc agttgttgct
    18361 gcttcttttt tcggttcatc atattttgtc aggtcgtacg cttcgatgat cgcgttcaat
    18421 ttttgtgaat attggcgatc tgtagcataa cgtccttcca aatatttggt tgcttctttg
    18481 tagtcttttg tttccgactt ccaagttggt ttgtagaaat caggattgcc agtcagtcca
    18541 tttttgatca agtcggcata gtcttccaaa ctttccttgt aagaaggata tttacggaat
    18601 tgtgcgcgga tttggtagct ttgtccggaa ctatcttgtt caagtgtatt gaaggtcacg
    18661 ctgcttcctt tatatgatcc tttgatacca aaaaggttat gatttggttc gcttgataat
    18721 aagctgtttc cagatccact ttcaaggata gcttgagcca tcatgactga tgcgtagatt
    18781 ccttcttttt gcccgatttc ctgtgcatca tctgcaatct ttttcaagaa ctgatcagtt
    18841 gtttggtttt gactgaaatg gaacgagcca tctaatccat ctaaaataga tgagccgcct
    18901 gtcagcgaac ctgaagcagc aggtaaacct gctaagttta ctcggacagc aaaatcaggc
    18961 gtgaaatctg aaatagaagt tactcgaact ttatctcctg gttgaggcgc atggataaat
    19021 tgtccgttcc caatatagat acctacatgg tgagtaacac cggaagaagg tccccagaag
    19081 acgaggtcgc caggttgggc ctgacttact ggaatctgcg tacctgcata ttgctgttcg
    19141 cctgtccagc caccgatata atgaccggtt gctttcatat atacgtaata agtcaaacca
    19201 gaacagtcaa aagtatttgg accttttgct ccccatacat atggttttcc aagatgcttg
    19261 aatgcttctc gaacgattgc ttgttggaca ttcgttgtat ttgtaggcaa tacagcatca
    19321 attggtgatt ttacaacaaa atcagaagaa gcagaagatg gattctctat accgctttga
    19381 tttgctgtat ttggacgaga tgaagcattg ttcgttccgc cattcgatga accattgttt
    19441 ggatggtttg gttctctctg agtatttcca ttgttattcg atccagatgg gtttgtttga
    19501 ttcgaagaat tcccgctgtt cgaattattg ttattattgt ttgaattatt tgaaccatta
    19561 ttattgttgt tattacccac atctggtttg tttggcgttt ccggatctgg tgtactaggg
    19621 acttcttcac taggatcagt tggtttctct gttgaagtat ccggtccagc tttaaattct
    19681 gcagtaatag ataaattgtt cgtacctact gtaaaggtct ttgcatcata atttacttct
    19741 ttggcaccat taacagcgac tgaagcaatt tgttcacctt cagctggcgt aatagtgtaa
    19801 gttaccttcg tttccgctaa taaaccttct accgttccac tttccgtaat atccaaaggt
    19861 tgctgttcag gggaatccgc tgtcgaagca gtcagttgga tcttaccaat caaagaagga
    19921 gcaattgtaa gggaatatgt ctcggctggc ttttcatttt ctgatggatc agccggatca
    19981 atttcagttg gctcggtcga tcctgttgtt gagttagttg ttccagttgg gtcttctgta
    20041 aaagaatccg ttgtttcact agtagctgag ctggatgtag tcgtatctgt tgtgactgtt
    20101 tgatcagcta tttgattatc tacggcaaat acggtattgg tcgacaaaac agacggagca
    20161 atcagccaag tagcagctag caaacgtatc gtttttttat ttttcataat aaactagtcc
    20221 ttttcctttc attgattttc tgtcttattc agcattcatt agacattttt tggaacagat
    20281 aatcgtgtcg aaaagctttt tcttttcata aatctgtctg tgtattctaa ataaaacaat
    20341 ttgtaaataa gcaacgagca ttcattcgtt tttctttgac gttcatttta ttgcatagac
    20401 cacctttgtt tggggataaa caagtgggga taaaaatggt tatgcatatg taaattatac
    20461 caaagtttgg aaagtatcac aaaaatttat aaaaataatg atcctaaaaa gaaaaagact
    20521 gaaatatgtg ataaacatct catacttcag tctttttcat taactattca taagacatta
    20581 ggtcttcatc aaacccgcta acgagagtag tgatcattgc tacgactaga ctaacagcca
    20641 gtcctgctaa gtaccagaaa aaagtaccgg aaatgaatgc aggcaatgtg gtcagactac
    20701 caaatacaaa agcgatcgct ttcacttggg caaatcccat tacagctcca ccagcagctg
    20761 caccaatgca agcagcaaca aatggttttt tcaatgggat cgcaattccg taaacagttg
    20821 gttcggtcac tcccgcaagt aaaatcgaag caaaagcaga accggagatc gaacgggttt
    20881 ttgaacgttt acttcgcaga aatacaccta aagctgcacc agccattcca aaattggctg
    20941 ctcctgtcaa cggaacgatt cggtcgaacc cataagcaga gatattactg atcatgacag
    21001 ggtttacagc ccattggata ccaaatatta ccaaaatatt ccaaccacca gcgatgattg
    21061 cgccactgat cggtccgtta atatccatca tccaagtaat tgcggcagct aaaccttcgc
    21121 caaggtaaac acccgcaggc ccgaatacca ttaacgtcaa aggaaccgtg ataactaatg
    21181 aaagtaaagg tacaaatact aattgcatat tttcgcgaat atattttttg aggaattttt
    21241 caacaaaaga ataaaagaaa atacctaaaa tcgccggcat gacagtagac gtatactgca
    21301 tcagtactac aggaatcccc agaaaatcag tagctgcttt gccactgtct gaaagtaaag
    21361 aggtcagatt cggttcaatc agtgctgcag caatgacagc cgcaatatat ccattcactt
    21421 taaacgtttt ggcagcagaa aaagcaagaa agattggcag aaaataaaag acggcattcg
    21481 acgcagcaga caaaatatga taagttccgc ttgtttcact aagccagcca atcgtagtcg
    21541 ctaaaacaac cagacctttt aatataccag aaccggcaaa cagcggaatg atcggcgtaa
    21601 agatttccga tatcaaacca aatagttttt cgatcggatt tagcttttct ttcggagctg
    21661 aatgatcgat ttgacgcgtc aattccttgt aagcaggagc caatccctga tccatgatta
    21721 tttctgcata tctatcgagt aaaatgaaat acttaatgga agggatttgc tgttttaatt
    21781 tttctgcatt ggctactggc tgttttttca atttgatacg aagccgagtc gcacatggaa
    21841 ggacagaatc aatattgtct tttcctccca actgttcaat cagcatatga atctgctcgg
    21901 acagtaccat ctgttcagga ttcattgtcg tttccattag aagaccactc cactcactaa
    21961 tataatattg gcgtaaggtg tcatttcgcc tgtacgaata aatgcatgac agttattcaa
    22021 ctcttttttc atttcttcat gtgggataaa gctaatcggt gtatctggta acaataattt
    22081 gattttttcc aatatttccg ggttcattgt ctttatttct tccgccaatt caatcgattg
    22141 tacctcaagt tcttctaaaa cgttttctaa aacagataaa aaacttggaa gaccgtttga
    22201 gacagccaaa tctatttttt cagtaccaaa ggggacaggc atgcctgcat ccccgatact
    22261 taatttatca aagtgcccca tttgtgcgat tactcgtgaa atatctgaat tgattacttt
    22321 tccttttttc atgtttgttt cttcctctca ttgttaattt tagactgctg attgttctaa
    22381 agcttcgcgg taagggatag aaggttgcgc accataagac tgcacagcaa cagaagaggc
    22441 tagatttcca taaaggatcg cttctttcaa gttactaagg tctggctgaa gtgtgctgct
    22501 taatgcgcca ataaatgtat cacctgcggc tgttgtgtca acggcatcca ctttaaaagc
    22561 agggacgata ccgtgttctt tttctgtatg atagaaagcg ccggcactgc ctagtgtaat
    22621 gattactgtt ccaataccta attcatggag tttttcggct gctgcgacca aactgttatg
    22681 atctgtcact ctgattcctg taatgatttc tgtttctgtt tcatttggta taatgatatc
    22741 tgtcttttca agtagttcag taggaatcgt ttcacgagct ggtgcaggat tcaggatcgt
    22801 tgtttttcct gcgtcttttg caatagaaaa agctaggatc gtcgcatcta agctactttc
    22861 aaactgagca ataataaagt cactgtttgt aatcagttgc ttgtttttta ggacttcttg
    22921 ttcatggaaa gcattatttg cccctgcatg gatcaagata ctattttctc ctgctgcgtc
    22981 taccataatc attgcttgtc cggttgtggc gccttggatt tcagctatcc cagatgtatc
    23041 gatgttttct tttgtcagta gatctaataa ctgttgtcct tcgctgtcag ccccaacgcc
    23101 tccaataaaa gatgtccgtg cgcctgaacg tttggctgcc actgcttggt tggcaccttt
    23161 acctccgcca gcgtgaaaaa tctcatgcgc atgcatcgtt tcgcctggct tgggcatgtt
    23221 ggttaaacga agggtagtgt ccatattaat acttccaatt actgtaaccg tgttcatttt
    23281 acaaacctcc aactatctca tttattttga tgggaaaatt attttttaaa acgttttagt
    23341 aaaacgtttt aatagttcga taaaaatata gcacaccttg aaagctattt caagggtgca
    23401 gttgaaaatc ttttttctaa tcgtacaggt aatctttttt cttcccattc tttttctggg
    23461 aattggatcc gatctaacaa taacttggca gatgtttgtc ccaattcgaa gattggttgt
    23521 gcgatcgttg tcagtttcgg cttgatatac tcgcacatat ctatattatc atagccaata
    23581 atgctgtagt cttcagggat gctttttcca gcttcctcta atccgcgata taatccaaaa
    23641 gctaattcat catttaaagc aaacacacca gttgcagcag aatcaagaag ttctgctgtg
    23701 atctggtagc caccttgttt tgagaactgt gtaggtaaga ggatcagttg gtcgtgaggg
    23761 atttggtaaa catcaagagc agatttaaac ccctcaatcc gagcgtggac attttccggt
    23821 ggattttcag gatagacaag ggcgatcgtt tgatgtccta gactaagcaa gtgcatgccc
    23881 gctaggtaac caccgcgaaa atcgtctgtt cgtacggcat cactaaatcc ttcagatttt
    23941 ttctgatcca aaacaatgaa gggccggcct tgttttttca aattttcgtt gattgcatct
    24001 gtagagacag cagaagtcgc gataatgaat ccatccacac ctcgacgtgt gagctcggct
    24061 agatattcga tttctttttg atgatcagaa tcagcattac ataatatcgt gacgaaattc
    24121 tgcttataca agatatcctc aattcctcgc atcagtgtac tgaagaatgg attcgtgata
    24181 tcaggaacga gtacaccaat tgttttcgtt tccttggtaa tcatttgtct agcaaaatag
    24241 tcaggctgat agcctaattc ttctttggca gctaaaactt tctgaacagt tttcggactg
    24301 aatttctccg tatttccatt taatatcaag gagacagttg tgattgaaac gccggaaagt
    24361 ttagcgactt ctttgattgt gatctttttt ttcaccatgt tcatactcct atctaaatcc
    24421 tgtggttatt ttcccatgaa atcaaaaaga agtaaatgaa aatcacgtgt gccagtactt
    24481 atttgctttg ttggatagct tcgattattt gtttcgttga gcgtactcgt gcagttttcg
    24541 gaaatatctt ttttatgaac aattgatggg attctttgtc acgatcactg caagcatctt
    24601 cagcaagcac gatatggtac ccgtgttgaa aggcatctaa tgcagtagca tatacaccgt
    24661 ttgttgtcgc tacaccgctt aaaatgatag tttcgattcc acgccggcga agttgaagat
    24721 caagagaagt accaaaaaaa gcacttggat tgtattttgt gatagtcaac atattatctg
    24781 tatctttcaa agaatccttc aaaagtaaat cagtgaattc tggaggtaca gaagcagtca
    24841 ttccacccat atcagtttgt tgactcaaat aagggaaagt ggagatgtct acgttcacta
    24901 aaactttcaa ggcagcggta cgtttcaatg ttcttactaa caaatcattg tttgtcagaa
    24961 tagatgctgc agtgtgtgga gagagtgtac cgttatttac gatctctttt tgcatgtcga
    25021 tcgcgacaaa agcagttttt gataaatcaa aaatcatatt ttcctttaaa tcattcatga
    25081 tgttccttct ttcaaataac aatgtttttt atgtaagtaa atcataaatc gtttatttgt
    25141 caactaaatt aaaggattcc tttctttagt ctagagaaat tcagtggtaa aataaataag
    25201 tgtgagaaaa cgcattcgat gcatagatat agcgagaaat atcgtgaaaa tggaggaatc
    25261 agagtgaagt atgtcgaagt aaaaaatgaa tacaaacgat acaaaatggg agaaacgacc
    25321 attacagcaa atgacgatat ttctttttca attgaaaaag gcgaattagt gattatactt
    25381 ggtccaagtg gagcaggaaa gtcaacgatt cttaatattt taggtgggat ggatacacct
    25441 gatgaaggtc agatcattat tgatgacaca gatattgcgc aattttcaga taaacagctt
    25501 actgcttacc gacgaacaga tgtagggttc gttttccaat tctacaatct cgttcctaat
    25561 ctaacagcaa aagaaaatgt ggaattggca acggaagttt ctcctgatgc gcttgatcct
    25621 gtagaggtat tgaggcaagt gggcctagct catcgattga ataactttcc gtcccaatta
    25681 tcaggaggcg aacagcagag ggtttcaatt gctcgtgcac tagctaaaaa tcccaaactt
    25741 cttttatgtg atgaaccgac aggcgcgctg gattttgaaa cgggcaagca agtattgaaa
    25801 ttattgcaaa acgctagcag acaacacggc aataccgttt tgatcattac acataattct
    25861 gctttagcgc ccatcgctga tagagtcatt cacattaatg atgctaaagt aaggtctgtt
    25921 gaattaaatg atcatccttc atccattgat gagattgtat ggtaggggga ttttatgaaa
    25981 acaagaacat atcttaaagc aggttttcgc gaaattcggc aatctaaagg acgattcatt
    26041 gcaatcatcc ttattgtcat gctaggaaca cttttatttg taggtgtcaa aactgctgga
    26101 cctgtcatgc aaaaaacgat ggatcactat gttggtacag caggactttc tgatttgcaa
    26161 atcgtttcta ctggtggctt gacacaaaaa gatattgctc aagcagaaaa gatcccagat
    26221 gcaaaagtag aaacaggaaa acagatctat tattccaata ctggcaaaaa cgaagtgatt
    26281 caaatatttt cttataacaa aaataacaag cagaacaagc tacaattaac tgatggaaaa
    26341 ctcccggaaa aaccaaacca gcttgtattg gatgaaaaag cggaagatga agggtataaa
    26401 atcggtgata tttatcagat tgattcagat gaattgaaag aaaaagagta taccatcacg
    26461 ggctttgtcc gttctccatt gttcatcaac aatttggaga gaggatacgc gaacgtcgga
    26521 aatggtagcg tcgattattt tgtctattta cctgaatccg tttttaaaac agatatttat
    26581 tctgtcttat atcttgattt tacaaacgta aagaatttga atacgtacag caaagcttac
    26641 aaagataaaa tggagcaaaa tcaagaaaag gcagaaaagt atttacaaga tcgacccgaa
    26701 gaacgcttag aagagctgaa aaaatcggcc aacgaagaat tagaaccggc acagcaaaaa
    26761 atagcggatg gcaaagcaca aacaacgcaa gcaagaacac ggttagaaga tgctaaaaaa
    26821 cagttagcgc aacagtcagc aactatccag cagcttcctg aagcgcaacg aacaatcgct
    26881 gttcaaacat tatctcaaca agaagctcaa cttgctgaac aagaaaggca attagttgag
    26941 aaagaacgtg aactggcctc tgcagaggaa gaattgaatc gaaatgcaga aaaaattgaa
    27001 aatttaacta aaccatcata cctatacaat gaacgttcag aaaatgtcgg ttttcaagaa
    27061 tttggtgatc tgtctgatcg tatcgctgcg attgccaatg tttttcctgt tttctttttc
    27121 tttattgccg cattgatcac ctttacgaca atgacacgta tggtagaaga aaaccgcagg
    27181 gaaatcggga cattaaaggc gttaggttat acgaaagttg aaatcgcaaa aaaatatgca
    27241 atctatgcaa gtctagcctc agggataggt attgttttag gaacgatatt aggaacgaat
    27301 cttttgccaa ggatcatttt tgagctgtct aacgagcggt atgatattgg gagtgcgctt
    27361 attttttatg actggccgcc gattttacaa gcagctgccg cattcttcat tgccgcattt
    27421 ggcgctgcaa tgatcgtttt attcaaagat ttaagagaac ggcctgctgc attgcttcaa
    27481 ccgaaagcac cgaagccagg gaaacgcatt tttcttgaat acatcactcc gctgtggtca
    27541 cgccttagct ttaatcaaaa aatcagttac cgaaatctct tccgatataa gtcaagaatg
    27601 cttatggcga ttatcggaat tgctggatgt gccgggctga tggttgcagg cgtgggattg
    27661 aaagattctc taagttctgt ttcagccaaa caatttggaa cgatcattga ctatcaagca
    27721 atcgttacat tggattcatc cacggaagat agtcgtcaaa aagcagcgga tatgctgcag
    27781 aagcaagaaa aagtaaatga gatcctagct attcatactc aaaccgtaga attgagaaaa
    27841 aaaggacatg cttcgcaaag tctgacagtg atcgtaccaa gtaaaacagc tgatttggat
    27901 cgttttatcc atttaactga tcttgaagag aacccacgct ccttgcctaa aacaggaatc
    27961 gctattacgc aaaaagtagc agaactattt gacttatcta caggagatca tatttcgctt
    28021 tatgatgaag atcaaaaaga atggaaagtc gaagtaaaag aaatcgtgaa aaactatcta
    28081 ggtagcttta tttatatgtc ccctgaatat tatgcttcag ttactgatca atcgatgatg
    28141 gataatgcat ttttgctgcg tacagataag atgacaacaa aagaagaaga aatgctttcc
    28201 gagaaactgc ttgccacaga cgctgtgaca aatacgtctt tcatgtccaa acaaatcgaa
    28261 acgcaagaag aatcaatggc gaacttagac tcggttgtct taatctttgt cgtattatca
    28321 ggactgctgg cttttatcgt cttgtataat ctaactaata tcaatatttc cgagcgtgta
    28381 cgcgaattat ctacaataaa agtccttgga ttttttgata aagaagtcac gatgtacatt
    28441 gttcgagaaa atatcatctt tactctttta ggaatcatcg gaggatttgg tgtaggatat
    28501 atattgactg acttcatctt gcaacaagcg tctatggaga atgtcatctt tccattagtg
    28561 atcacatggt gggcttatgt cttatcagca ggattaacta tcgtatttac ggttattgtg
    28621 atgattgtta cccatttcaa attaaagcat atcgatatga ttgatgcgtt gaaatcgaat
    28681 gaataaaaac agaggttgtg aaatcagcgg tttgacctga gtattagaga aacaaacggc
    28741 aaaatagttt ttcatatttt gccgtttttt gagctaatac cgaaggacag ctgattgaac
    28801 accatgaatc agaggttgta aaaaagccgt cctgcatcga gcaaaaagaa tactcaaata
    28861 aaattagctc ctcatgtttt acatttgaga agactgattg ccgtagataa aagcttttga
    28921 acaccattta tagaagaaac aagaatattt tgctatttta aacaagagga tagacaaata
    28981 catgtctgat ctcttgtttt ttattgggca acagacctct tagaatgtat aaagataaat
    29041 tttacaaacg ctttcggttc agttataata ataaatgata acttgtatat ataagttgtg
    29101 gtaggtaata aatcagttga atggaggtaa atatccatga catttaaaga caaagtcatt
    29161 taccaaatct atcccaaatc ttacaaagac agtaatggtg atggaattgg agatttaaaa
    29221 ggaatcaaag aaaaactccc gtatctgaat gatctaggca tcgacatgat ttggctaaac
    29281 cctatttatc caagccctca aaaagacaac ggttatgata tctctgatta cacagccatc
    29341 gatcctatct ttggtacgat ggaggaattc gaacagctaa tagccgaagc aaagaaatac
    29401 cggatagaaa tcatgctcga tatggtgctg aatcacgttt cgacagaaca tgaatggttc
    29461 aaaaaagcac tagcagggga ccagcattat caggacttct tcattttaag agaagagcca
    29521 acggattggg tatcaaaatt tggtggaagt gcttggtcgc catttggaga tacggggaaa
    29581 tattatttgc acttatatga tcggacacaa gctgacttga actggcggaa ccaagcagta
    29641 agagaggaac tattcaaagt tgttcgtttt tggatggaaa aaggggtaaa aggattccgt
    29701 ttcgatgtta tcaatgttat cggtaaagac gaacaattga aaaataataa agaaaatgat
    29761 ggcaaacctg aatatacgga caaaccaatc acccatacgt atctaaaaga attgaaccaa
    29821 gcaacgtttg ggacggattc cactatcatc acagtcggtg aaatgagctc tacgacgatc
    29881 gaaaattgta tcttgtatac agaacctagt agagaagaat tatcaatggt ctttaatttc
    29941 catcatttga aagtcgatta tgaaaatggg aataaatggt ctactcctcc atttgatttt
    30001 gcagaattaa agcgactatt tcatacatgg ggagaaaaga tgagtgaggg taacggctgg
    30061 aatgctctat tttttaataa tcatgatcag ccacgtgcgc tcaatcgatt tgtagctatc
    30121 gatcagtatc gaaaacaagg agcagagatg ctagcaacca tgatccattt gaaccgtggg
    30181 acgccctata tttatatggg agaagaaatc ggcatgatcg acccagacta ttcatcgatt
    30241 tccgactata ttgacgtaga aagtttgaat gcttataagt tactccttga acaaggattc
    30301 acagaaaaag aagcgtttcg tcggatcaaa gcaaaatctc gcgataactc tcgaacaccc
    30361 atgcaatggt cagacacaga acaagcagga tttactacag ggaaaccttg gttaaaagtt
    30421 ggaggcaagc tagaagagat taatgtagaa aaagaactat cttctgaaga ttctattttg
    30481 tcctattaca agaaattgat tcggctgaga aaaacatatc caatcgttgc acaaggagat
    30541 tatcatgctt atgaagcaaa tcatccggaa gtttatggct ttcttcgcca atttgaagga
    30601 cagcagctgc ttgtattaac aaatttctat gataaagata caaggatcgc catcccagaa
    30661 ggattcacag aagccaatat tcttatcgat aattattccg atactgttct tcatcaaagt
    30721 ctggagctaa aaccatacca ggcaattgct ttgctgaaaa attaaaacaa aaacacaaaa
    30781 cgtcgttcct acgagctatt ctcgtaagat cgacgttttg tgttttattt aaaataatct
    30841 tcttcagaaa atgaagagtt ttcatactct cctttatcgc cataaaattt attgtagcgt
    30901 tgtttgaatt tacggaaaat aaaagtaacg agtaatttga ctaacgtata gataggaata
    30961 ccaaaaataa cgcccacaat tcccattaga tcacccatga caagtaaaac gattaagatc
    31021 gtaatcggat ggatctgtaa acgatcaccc attactcgag gaatcaccaa gtcaccgtgg
    31081 agaagttgta cggcaaacca gacaatgaca aatttgacag ccataaaagt agagtcttgg
    31141 aatgcaatga tcaaacctgg aaagaaggcg ataaacggcc caatatatgg aatgatacat
    31201 aacaacccag cagaaatagc taaaacacta gcaaattcta atccgatcag taagaaacaa
    31261 acccagtaga ctgctccaag gataaatgaa gcaatgattt gcccctttag aaatgaaccc
    31321 aattgttgat tagcaatctt tgtcaaattt ttaaaatctg tacgaaatgc tggtgggaca
    31381 atcgctaaaa ctgactgata aaatttttga ggatctctca aaaggaaaaa agcgacaatt
    31441 ggaccagtaa ataaagtaat aaaaatagct gtaacagttg aaaaaatgtt gctgatccgt
    31501 tgtgcgccac tttcccaata atttccaata aatccagcta tatcagacgt cacgtcgtca
    31561 atagaagcga aaaattgatt aaatgaatcg gcaaaaggtg ttttctccaa aaattgtcgg
    31621 agactctctt gaaaatcttg aaacaaatct ggcaaactac tgatcaatgt ctttgcctgt
    31681 tcttcaagaa aaggaataag ccatatgctt ccaagcccca ataaaaataa aataatcaca
    31741 taaacgataa tgactgacaa gttcctcgaa aggtgcttgc tcaaacgttt gatgactggt
    31801 tccaaaagat aatacaagat cagtgcaaac aataatgggg gcaagatagt agcgataatg
    31861 attccgacag gcttgaatat aaacgagatc tgatggaaaa aataaatgat cagcgcaagt
    31921 aagataacta ttcctaaaac atagtaagag gtttttcctc ctaaaaagcg gatcaaacga
    31981 ttcgttgtat ctgtttcttt tttcactctt tttcctcctt tatctataac ttcattatag
    32041 acaaaagcgg gtataaaagg aaaatgatag aggttgattg caaaaatatc gtcaatcatt
    32101 catataaact ttctcatcaa ttaaaataag aaaacgcttg acagttcttt taaccatatg
    32161 ataaattaaa tcctgttgct aaaacgtaac tattacggtt tgcgaaaagc gaatcggaac
    32221 attcaaatga aagaagatga gaagaggagt gtcataaatg aaacgattga taggtatatt
    32281 ggccatgctg gttttagcag gtatgttaac tgcttgcggg gcaagtggga aagccgagga
    32341 cagtaaagaa aaattgagcg tgatgacgac cttttatccc atgtatgatt ttacaaaagc
    32401 aatcgtcggg gatgaaggag aagtagagtt attgattcca gcagggactg attcccacga
    32461 ttatgaacct tctgctaaag acatggcaaa gatccaagat acagatatct ttgtttataa
    32521 tgatgaaaac atggaaacat gggtccccgc aatccaaaaa acattacaag aaggcaatgt
    32581 ccatacgata aaagcgacag aaggtatgct tttacttccg ggaagtgaag aaggacatga
    32641 tcatgaccat gaacacgggg aagaaggcca tacacatgag ctagacccac atgtatggct
    32701 agctccaagt ttagcaatca agcaggtagc aaacatacgt gatcagctga ttgaagctta
    32761 cccagaaaaa caggaagtat ggacaaaaaa tgcagcagcc tataccgaga aacttcaagc
    32821 actccatcag ctttatcaag aaacctttaa gcaagcaaaa caaagatctt ttgtcacgca
    32881 acatgctgca ttcaactatc tagcgttaga atatggattg aatcaagtat cgattgctgg
    32941 tctttcttct agtgaagaac cgtctgcggc gagaattgct gaactgaaac actttgttaa
    33001 agaacatgga atcaactata tttattttga agaaaacgcc aaagatagta ttgccagaac
    33061 gttagcaaac gaagcaggtg tatctttaga agtattgaat cctttggaag gattgacgaa
    33121 tgaacaaata gaaaatggag aaaactatct ttctatcatg gaagcaaacc tcgaagcgtt
    33181 gaaaaaaacg acagagacag aaaacccgct agaagatact ttgaccccca aaaaagaaaa
    33241 gagcgtctac aacggttatt ttgaagacga ggatgtacaa gatcgctctc tttcagattg
    33301 ggcaggaact tggcaaacag tagatacgta tgtagaagat gggacttttg atcctgtttt
    33361 tgaatataaa gaaaaattga atcaggataa gacagcacaa gaatataaag aatattatac
    33421 gaagggctat caaacagata ttgcttcaat caagatcagt gagaaagaga tggcatttac
    33481 gtttaagaat ggaacaacga aacgttcaaa ttatcgttat gtagggaaag aaatcttgac
    33541 ctacgaggca ggaaaccgtg gcgtaaggta tctattcgaa gcagaagata aggaaagtgg
    33601 cgcttttaga tatattcaat tcagtgatca cacgattgca ccggctgact ccgaacattt
    33661 tcatttatat gcaggaaatg aaagtcaaga agtattgctg aaagaaatgg agaattggcc
    33721 aacattttat ccagatacaa tggatggacg tgaaattgca caggaaatgc ttttgcactg
    33781 ataggcaaaa aagaaccgaa gggtttggat cggctggtca tttagtcggt ccaaactatt
    33841 cggttctttt tatgaaatca atttctttaa tccacggata gaggctggga tggtctcgcc
    33901 gtttgccaac gtgacttctc tggttttttt attaatcgac cgcacatttt gtgtattgat
    33961 aacataggat ttatgacaac ggataaaatt ccgatgcatt ttctcgattt ctttgatctt
    34021 ctcatagaat tgtaattggg catgagtcaa atggacttcc agtttatgtg gcgctcctag
    34081 cgaagtagaa aaatattgga tgtctttgat cggtaaaaat ttgatctcat cattaaactc
    34141 tattttgaag atatcttttt ggatttggga catttgaaaa tcttcgaaaa ttttgctcag
    34201 gatatgctcg acattttctt ttaaatcata aagatcttct ttgacgatat aatcagtcgg
    34261 ttcgatgttg ctttttaaga ttttcatcga catttccgta tgggaagtca catagattat
    34321 ttttcctaaa ggatctaatt cacggatcaa tttaccgatc gctacaccat ccatttcact
    34381 gtcttctagt tcgatatcta aaaagtaaat accaaaagaa gaagttctga tcttggctgc
    34441 attgagaagt tcttccggat cagaggtaga aatatggaca taactgtcta agttttcaat
    34501 catgattcta tttttgatca ccgttgataa aacttctaat tgttttggat cgtcttcaca
    34561 aatataaatg ggaatcatat cattactcct ttattttatt tgtatataaa tcgtttgaga
    34621 aaaacgctgg ttttcaattg atgtttcaag gaaaagataa ggattggtct ttgtcaattc
    34681 atccaagata aacaagccaa ggccttcgtt ttttggattt gtttttgttg agaacccttt
    34741 ttgtttcaac tggtttaacg gtaatgtatt tgttgttgta ttgatcacac gaatcatcac
    34801 ggaatgattc ttcttgagta tggtcaattc gatttttttc ttctttgcag cactagctcc
    34861 ttcaatcgca ttgtccaaga taataccaag catacgtaca aggtttaccg tatgtttcgt
    34921 atccagttcg attggctcag gaaaatgaag ctggacgatc aacccttttt cctgtgccat
    34981 catgagtttt aatgacagta aactacggat ctcaggaact ttcatattat ccaacatact
    35041 tagattggcc ggaaaaaggt tcatcatctg gcgtgtaggt aatatcgttt gatcataata
    35101 agaccgtaat ccttctaagt cgccttctga aatatagctg tgaagagaaa aaagcagatt
    35161 ttggtaatca tgtttgaatt ctctcaagtc ttgatagttt ttttctagat ctttgatata
    35221 atcctgttgc atcctgactt gttgctctaa taactgatca gctaatttct tattagagat
    35281 tttccaataa taaaccaaga tgatcaggcc aacacacaga tatagaatga aaaaactcgt
    35341 attcaaagct aagacatcag gtgtttcacc agaaaaacgg gtataaaaaa taatgatata
    35401 gtatgtaaat aatatcaatg tcccgatcgt accgatcata cggcggtcca cagtgtgaaa
    35461 ccaagtctct aacgattttt ttaaacaaaa agctaataaa gcagataaaa aagcggataa
    35521 gacaatgtga aaatactgca atgaatctcc tggttcaata accgaagatt tcaaaacaaa
    35581 aaaatcgccg atgcttgtta agtgatctcc taaaagcgac gtcaataacc caaaaggaag
    35641 cgcgtaaacc aattgttgac gcgaagtcga aaagaagaaa aaagtaagca tcagcattcc
    35701 tatagcaatt agagcagtaa aaatccctaa aatcgaatag acccatccaa tcaaaataca
    35761 agaaatcaga atgactcccg caaacagata tttgtatcgg atgtgatggt caatcaataa
    35821 gatacaaatt gtgtaaatca aatattgcaa cgctatggac cataaaaaca taaagtacag
    35881 ctcccattga tttttaccaa attatagcac aattggcgta ttattttttt aatttttcag
    35941 ggattttgaa ttcagaactc ataccaaagc agcagccaga tacaaaaaag tcagataagt
    36001 tagttaattg tttaatgatt gtttttttca tgaaagattc ctccaaaatt catcaagtag
    36061 tttgtaatag gaagcaacgt agctatttct aaaacaatcc caagtagcaa ataggtagaa
    36121 aagtaagaag ctgagaaaaa taacgtaatg agagaaaaaa ttagaaacat gctgatcgcc
    36181 ttctttaata atgggggacg tttctcgggt tcaatgggat tgattgctgt acctcttgat
    36241 ccatagcgaa gcagtaacaa aaagcagctg attaacaaaa agaccatcat tgggaaggag
    36301 atagtcaatt gcagatgttt catcaccaag ggaacgcccc ataaataaag tagtgtccac
    36361 agcagacaaa cgaattcaga gtcggaatgc aatccataag catatctgcg gatgcagata
    36421 taagaaagaa aggtgattcc tgtttccgcc catgagcctg tcaccagaga aaagactaga
    36481 acgaccgcta gttttccaag attattcaat aaaacttcta agacaaattt tacttggaca
    36541 tacaccatat cttcttccga tttgtctccg ctgaataagg cttctaataa tttgttcaca
    36601 actttatctt tcatctcata cgtacctcca ccacaaattt tatgctaaaa aaaataaaaa
    36661 acgtcttttg tttcataaaa agtggttttg acatcaaaac cgtcatgatc tcctaaaaaa
    36721 atcttcgttt tccaagaacc ttaccaaaaa aagtgacagt tttgatacga aaagtacttt
    36781 ttatgacaag tttgtgcttt ttcgagtgat ttatgttaaa aaattactga ccttataaaa
    36841 ggtgatggag ggattcttat ggaaaatgaa caattgtttg aagtcggcga aacatatgca
    36901 tttaaatctg atttatttga atcaccaata aaaggaaaaa tagaaaaaat ctatgaaaat
    36961 agtgtgatga tacgtgtcat gaaatgcgca gtagaagaca atgataccgc tcataatctg
    37021 cactggcagt tagttgtacg caaatcaagt acaatagaag aataaaaaca gataaaatgt
    37081 tgagagcata aagaggttgt gagtctcccg tttagctctg agttacaagg aataatgtta
    37141 aaaaacagct tttcatgttt tatgaatatt gccttgtgac cgaggtgttg gcaggagaat
    37201 actgtttatt tgaaaaaagg gctgcgacaa gacttttgtc acagccttta ttttcatgaa
    37261 taggagttac ttttggctac ttttagagaa gtagctttta aggagcagat aaagtcaagg
    37321 cttttatttc tataaatgaa gtagtaaaat gaagaacaga ttttattaca ggaaggatgc
    37381 cgataattgt gatcattgtt gcaggaacga tcggtgcagg gaaaagcaca ctaactgaaa
    37441 tgcttgccca agatttagaa acaaaacctt tttatgagaa cgtggaagat aatgaagtat
    37501 tgccgctatt ttattctaat ccagaaaagt atactttttt attacagatt ttctttttga
    37561 acaaacgctt tttggcaatc aaagatgctt tcagccatga tgacaacgta ctagaccgct
    37621 ccatctacga agatagtatg ctgtttcatt tgaatgcaga tttagggcgt gtttctgaag
    37681 tagaagtaaa gcagtatgaa ggtcttttag aaacgatgct gaaggagtta gaagaaattt
    37741 cgccacaaaa gaaaccagat ctactggttt atattcgtgt atcctttgaa actatgttag
    37801 cgagaatcaa aaaaagaggc cgggaatatg aacagctaga acaagatcct gaactctatt
    37861 cctactataa agaactcaat cgacgatacg aagagtggta tgaacagttt gatatatgtc
    37921 ccaaaatagt gatcgatggg gacaaatatg atttcgtagc cgatccggca tgtggagaac
    37981 aaatcgtaca agaaatcaag atgcgggcaa agaaaatgac agaagaggca gatgcccagt
    38041 cgatccgcta cactacaaat aacccgaaag caaagggaat ctttacaact aaataatata
    38101 aaaactaagc aaattgctca ctcgcagata tttctctgtg agcagcatct tgcttagttt
    38161 ttttgattca ttgagatcaa atagtgaacc gattcgtatg ataaaattgc cataaatgaa
    38221 atgtctgagt gagggccatg atcaaaaata aaatggaaac gatcaaaatc gaatgggcgc
    38281 caaacagatg atgacagaaa acaaggacaa tagctcctgc gataaaggca agaacgacac
    38341 ttagatagtg gaaaaatcga tcaaaatctg ctttttcttt agaaatacaa taatcatata
    38401 agttcgttgc tacccctttt aaatttccag ttgtaaataa attagtgtag gcacgcccgt
    38461 tgattttatc aaaagctacc cactggatcg atgcagtaaa agcaatcaaa atcgttacta
    38521 atgcgggatg ctcatggacg ggtgtcaaac taacaaagaa aaaaatcact gcttcataat
    38581 atagaacaaa caagcgccag aaatgttttt ctttttttct aaaataatca attagatact
    38641 ttgttagaag aatccctaag aaaaagaaaa gggtagacaa tactttttta ccaacactta
    38701 gccattctcc gtcaaatgct tggatgatcg atagaatgat attgccagtt tgagcagagg
    38761 caaaagcacc atattggata taagtataac tgtccatggc tcctccgata aatgtcagca
    38821 aaagtcctat tgtacgcccc tcgtgaaagg aagtctgcat ttttttcatc accttttatg
    38881 aatatttttg tcttccttat cttagcataa acgattgaaa aaaaggaaaa attttcagaa
    38941 aactaaaatc atatcgcttc ccattttcat ttttagaaag gtctgttagt ataaagaaaa
    39001 aatagacaac gaaactttaa ataaccaact tgaaataaac aaattcaaag aagaaagatg
    39061 ggaaggaaat caatcagttg aatgaaaaag aaattctccg attacaaaaa gaattgaaac
    39121 gctgggagaa caagtataaa aagcttcaac aagtctttcg gctacaagaa gaaatcattg
    39181 ctacctatga agcggcttat ggcgaagcac ccggacttat tgaggaagaa gtacaagtaa
    39241 aagaaagtga aggaaacagc tctttcttta aaatgatgga gaaacgttcc tataatcgct
    39301 tcaatcaaga acaaaaagca gctatcacat atgatatgaa gaaacatctt cgaatcatag
    39361 caggagctgg gagcggcaaa acgcaaacaa tctgtgcaaa agctgtttat ctgatgacgc
    39421 aaaaacaagt agacgaagaa cgcatactaa tgatcacttt tacaaggaac gctgcaaatg
    39481 aactaaaaaa acgagtagat aatttcagcc agagaaaaac cgctgtccat atcggaacat
    39541 tccatagtat cttttttagg atatacaatg aaatttgtcg aaaatttcct gaagtagcaa
    39601 tgcaaggaat acaaggagac ttttcaaagg atactgcaca aaaagtgaat gctgttttgc
    39661 aacagctgat acgtaaatat aatctttata tatttgatca atatggagaa aaaacgattg
    39721 cttctcggtt agactattgg cagaatatga acctttcagt agaagaaatg gttcagttag
    39781 ttaaagaaaa atatgattcc attgataaga atgcacgaca gccgatatca gaacgactgt
    39841 atggattgct cacggaactc caagaacaaa aaagaagcca gcaattgcta gagttcaatg
    39901 atgtactcca aaatctgaaa agcgctttgg agaatgagga gatccagcat tatatcggcc
    39961 aaaaatatga ttatctattc attgatgaat ttcaagatac taatccactt caatgggaaa
    40021 tcgtgaaacg gatgacaaag gaaaacagga tcaagttgat tgttgttgga gatgatgatc
    40081 agagtatcta tggattcaga ggatcagagc cagcatacat caagaacttt gaaaaagaat
    40141 atcctaccaa aactcttttc ttattaacta attatcgttc tcgggcagct attgtccaag
    40201 gagcaaatag attgatcagc tataataaaa atgatcggat accaaaggcg atgattccag
    40261 cacaaaaaga agcaggtgtt atggaagcct atttgttttc tgatactaaa gcagaaagtc
    40321 agtggctaat caaacaaatt cagacattta ttcaaaaaaa tgggaaatat aaggaatcaa
    40381 tcatattata ccgatcagct tcacaaacgc agcagcttgt ccaatctctg ctgaaaacga
    40441 atattccttt tgtactggaa gcagatagtc catatgaagg tatctttggt atcaagtctt
    40501 tccaacattt ctatcaaaaa attgttcatt ggcaaacagc actgaatctg caaaagaaaa
    40561 atcaggccta ccagcaattg ctccggcagc tgatggcaga ctgctacctg aaaaaaagtg
    40621 aatgcgatca atacttttct cctaaatatc aaaatatatc cgttgcagat tatattttgt
    40681 cgataagccc caatttaaaa tcgaaatctg cagaaatccg agagtttgag gaagcgttgc
    40741 gtaaaacaga ccagcatcaa gaaatctatt cgcttgttca aagctatctt catctgccac
    40801 gtatagctaa ggaaatcgac cagagtgatc aagaatggat acgagaagaa gtaaagcagc
    40861 atgctacttt cagaagactc caagccttat cgcaagaaac ccaagcgaca gctaaagaat
    40921 taaaaacccg cttgattgct tacagacaag gaaaacttga tgcactatgt atccagagca
    40981 ttcacaaaag taaaggtctt agttaccgaa atgtcttttt gattggttgt aacgaaggaa
    41041 gtttgcctta taacggagcg acagaaaaga aagtaatcga ctttaatgaa ataaaagcag
    41101 aaccagtaac gacgatagaa gaagaacgaa gactatttta tgttgcgatg actagagcaa
    41161 gaaatcgtct gtatctatgt gtacctcaaa tgaaaaattc aagaaaattg aaagtatcga
    41221 gatttatcaa agaaaccggg agtcgtgtga aaaaaggaaa gtgata
//
LOCUS       DAFBVQ010000017        41152 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.017, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000017 DAFBVQ010000000
VERSION     DAFBVQ010000017.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 41152)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 41152)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..41152
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.017"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            238..480
                     /locus_tag="LLC22_001103"
     CDS             238..480
                     /locus_tag="LLC22_001103"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3781 domain-containing protein"
                     /protein_id="HBK5434396.1"
                     /translation="MENELLENLGRLHTTELGVIRIKKNLSLNVENVIEWCKEKISLS
                     NAEITRKGKNWYITIDNCIITVNAYSYTVITAHKVK"
     gene            477..947
                     /locus_tag="LLC22_001104"
     CDS             477..947
                     /locus_tag="LLC22_001104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002606082.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBK5434397.1"
                     /translation="MINFSIKELNAFAVIGQEVELTNYQKKNIQISTQFWRKFNSSLK
                     KAYLSQSGNWVKYAFMERRNGKLYYFCSIPQRTITPEGFLYKEIPSYKYLVVEHIGAM
                     DKIYETYGKIYEEIIPSTSYIPIKDIILHFEKYDYRFHWNSDNSVIEIWIPIQD"
     gene            1075..2289
                     /locus_tag="LLC22_001105"
     CDS             1075..2289
                     /locus_tag="LLC22_001105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="XRE family transcriptional regulator"
                     /protein_id="HBK5434398.1"
                     /translation="MNDKNFIEELRQKREEYGVTQTRLAVACGISREYYNRIEKGKQP
                     LNDELREIIEKQIERFNPQEPLFLLIDYFRVRFPTTDALAIIRDVLQLKSNYMLYEDY
                     GKYGYESKYVLGDINIMCSMQEHLGVLLELKGKGCRQMECYLLAQERSWYDFMLDCMT
                     AGGVMKRLDLAINDKAGILDIPKLKEKYKAGECMSYFRMQKDYSGTEKCGSDLPKNTG
                     ETLYLGSTSSELYMCAYQKNYEQYVKNGTEIEDTEIKNRFEIRMKNERAYYAVVDLLT
                     YRDAERTAFSIINHYVRFVDREDDKPKSQWITNDDWAWFVGENREPIRLTTKPEPYTL
                     QKALHWLQRQVAPTIKMVQALDRENRTTILKDMIEQAELKDKHKHLLQLEKSTIEERI
                     DTAVPQENDGIF"
     gene            3278..3487
                     /locus_tag="LLC22_001106"
     CDS             3278..3487
                     /locus_tag="LLC22_001106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008394616.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA wybutosine-synthesizing protein 3-like
                     protein"
                     /protein_id="HBK5434399.1"
                     /translation="MNCLERFYRKGVCVIDNAVKTIQKKNGKCGIGNRGKTKIVVKEH
                     FSEKGKTMEELLTDVMLEKAKQTIA"
     gene            3599..5212
                     /locus_tag="LLC22_001107"
     CDS             3599..5212
                     /locus_tag="LLC22_001107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003019515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5434400.1"
                     /translation="MKQQIYNTALYLRLSRDDELQGESSSITTQRSMLRLYAKEHHLN
                     VIDEYIDDGWSGTNFDRPSFQRMIEDIEAGKINCVVTKDLSRLGRNYIMTGQYTELYF
                     PSHNVRYIAIDDGVDSEKGESEIAPFKNIINEWVARDTSRKVKSAFKTKFAEGAHYGA
                     YAPLGYKKHPDIKGKLLVDDETKWIIEKIFSLAYQGYGSAKITKQLRAEKVPTASWLN
                     FTRYGTFAHIFEGKPESKRYEWTIAHVKAILKSEVYIGNSVHNMQSTVSFKSKKKVRK
                     PESEWFRVENTHEPIIDKEVFYRVQEQIKSRRRQTKEKATPIFAGLVKCADCGWSMRF
                     GTNKTNKTPYSYYACSYYGQFGKGNCSMHYIRYDVLYQAVLERLQYWAKAVQQDEEKV
                     LNKIQKAGNAERIREKKKKASTLKKAENRQNEIDRLFAKMYEDRACEKITERNFVMLS
                     SKYQKEQIELEQQITSLREELSKMEQDMIGAEKWIELIKEYSVPKELTAPLLNAMIEK
                     ILIHEATTNEDNERIQEIEIYYRFIGRVE"
     gene            5247..6458
                     /locus_tag="LLC22_001108"
                     /pseudo
     CDS             5247..6458
                     /locus_tag="LLC22_001108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340024.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
     gene            6481..7407
                     /gene="glsA"
                     /locus_tag="LLC22_001109"
     CDS             6481..7407
                     /gene="glsA"
                     /locus_tag="LLC22_001109"
                     /EC_number="3.5.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaminase A"
                     /protein_id="HBK5434401.1"
                     /translation="MEVKELEQLIGKNFHYYQTGQVADYIPALAEVDPKQLGMAIYDL
                     DTKQLIEGGDADVRFAIESMSKVPVLLLAIKDNGIEKVFQTINTEPTGFAFNSIMNME
                     INHRKHPMNPFVNAGAIATTSLIAGKDADEKFERILSFMKEICDDPNITLNEEIYHSE
                     SRTGDINRSLAYYMKGNQMIEGDVPEILDAYFRQCSLNVTATGIAKLAAVLANKGIAP
                     WNGKQIITEESATIVKSIMTTAGLYDESGEFSVHVGVPAKSGVGGGLMAAVPNRYGIG
                     VFSPALDPFGNSAAGIQLLKDVVKELDADIFE"
     gene            7615..9075
                     /locus_tag="LLC22_001110"
     CDS             7615..9075
                     /locus_tag="LLC22_001110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434402.1"
                     /translation="MLENYIERNIFRKVYLCEQLFEFQEIDIEQTAISLRVTTPTILH
                     DLESLAECLEYCIKEQVREKHKYKLVFKHGIALSELTQFLYGQSYFLKFLSYYFNGIF
                     TSTELADLEFISLSKVYTIKKIVLDFFKENDYLKNKEIIIPEFDSRNILLALVRYVNW
                     EGYENKNPYVEEACNELIDYVETHFFKRRYSEDEKSFIIREIEIAIGRKAFPLGLKEE
                     DKKSAETKPLFQLVCQGLEEQKGILDLQEEDVYYIFSLFNSRNYTNENMELLRKDFEV
                     VYKNFVLNDLSLNELILQIISIAEIDDAENFIFKQSFLQFVRTLWADGQVFLPERIYL
                     LSEKEQLLYGKIVEILEEWKKKNQIQLRWNENFIRKFVKSLSLINSEQAGRQEIEIFV
                     VSESSVKQFFYRTQFHLYAEEGIAEINPILFRSLEELPDECLCAKKRVVLCDAASYQN
                     GLETEKTKIYPISLKGANIHLYHIAQELHLLKKHIS"
     gene            9296..11059
                     /locus_tag="LLC22_001111"
     CDS             9296..11059
                     /locus_tag="LLC22_001111"
                     /EC_number="2.2.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-deoxy-D-xylulose-5-phosphate synthase"
                     /protein_id="HBK5434403.1"
                     /translation="MSTVLHVLDAINSPADVKKLSVEEMKQLAEEMRQKILQKDSDVG
                     GHVGPNLGVVELTIAFHYVFDSPKDKIVWDVSHQSYGHKLLTGRKNGFEKGHYREVSG
                     YSNQHESKHDYFTVGHTSTSISLATGLAKARDLKKESGNVVAFIGDGSLSGGLAFEGL
                     NNGGVLQSNLIVLVNDNEMSIDENHGSLYKNLAELRQTNGKSSNNLFKAMGFDYRYVD
                     NGNDLETVIRLFEEVKDIDHPIVLHVHTEKGRGYQPAIDNKMKYHWHVPFDLSTGEAK
                     QVTSGETFNMIIMDYLDKKMQTSTAPIAAVNAAIPGAFGLKTFQEKHPDHYFDVGIAE
                     QHSITFASALASQGVRPVVFQSSTFLQRAYDQLSHDLAINENPVIILVGGGTISASDR
                     THQGTFDIPYLSSIPNIKYLAPATKEDMISMLDWAFEQTAQPVAIRIPTHGVEHGTAI
                     ANDYSIPAYQTVNNGGKVAILALGGFLELGKETVKAFRKKGIEATLINPGTITENDVE
                     TLDKLKETHELVITLEDGSLSGGFGENISRYYGDSSMNVLNFGAEKEFTDSVPVGQLY
                     ERYHLTPKQIVEDSLRVLNIQ"
     gene            11143..11601
                     /locus_tag="LLC22_001112"
     CDS             11143..11601
                     /locus_tag="LLC22_001112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ASCH domain-containing protein"
                     /protein_id="HBK5434404.1"
                     /translation="MYQQVEEYVKKFQEKYPSYQSEKLGFFSFGDTEKMADELSELVV
                     KKIKTGTSSGYDLYKQENEPLPKVGQLDVVLNGKNEPVCIIKNINVTILPFSEVTKEH
                     AWKEGEGDRTLAYWRKVHAEFFKHAYKEALNIEFTEEKLVVYEEFEVIFF"
     gene            11710..12393
                     /locus_tag="LLC22_001113"
     CDS             11710..12393
                     /locus_tag="LLC22_001113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBK5434405.1"
                     /translation="MDTLEQIKGGVVVSCQALENEPLHSSFIMGRMALAAKEGGAVGI
                     RANTTEDINEIKRIVDLPVIGIIKRDYDGSEVFITATEKEVEELLETQAEIIALDATS
                     RKRPTEKTTAELVQMIHEHGRLAMADISTFEEALQAQEDGFDLLSTTLAGYTEYSRKT
                     QTPDFDLLNQIIEQVDIPVIMEGHTDSPEQVEKAYELGAFSVVVGSIITRPQLITKRY
                     VEAASKANN"
     gene            12540..13154
                     /locus_tag="LLC22_001114"
     CDS             12540..13154
                     /locus_tag="LLC22_001114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavin reductase family protein"
                     /protein_id="HBK5434406.1"
                     /translation="MFERSPSELTERENYKLLIGSVIPRPVAVVTTKSAKDIVNIAPF
                     SYFNIVSSNRPILSLAIQRKQDAVKDTAKNILETREAVIHILDEDNVEEVNKTAANLP
                     NEESELYLTDLTLTDSVIISVPALTEAKVRFETSLYEHVEIRNKNKVTADLFLLEVQK
                     YHLNETVYDDKTGRIDPRKLNAVSRLAGNDYAAIGEIFTIARPE"
     gene            13170..13376
                     /locus_tag="LLC22_001115"
     CDS             13170..13376
                     /locus_tag="LLC22_001115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434407.1"
                     /translation="MLKISYKPSTDSKEMKKEYETVNDFLQGQYLEVPPLQDHFVVTT
                     VTLDGKEIEMPDQTISGLFNYFNK"
     gene            13917..15047
                     /locus_tag="LLC22_001116"
     CDS             13917..15047
                     /locus_tag="LLC22_001116"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBK5434408.1"
                     /translation="MGPYLTLSMIGLLEVYSASSYLLLQADENTKSLLLRQLIFIFLS
                     WSVIFLARSVKLHYLLHPKIAGYGLALSIFFLVLVRIGIFGVTVNGAQRWISLFGIQF
                     QPSELANLFLIFYLSWFFRDGNSSPKDLKKPFLITVGITFLILFQPKIAGALMILSIA
                     WVIFWAAAVPFKKGIYLIVTFSALLIGAAGGVLYLGNKGWLPQMFNHAYERIATLRDS
                     FIDSHGAGYQMTHSFYALYNGGIFGRGLGNSITKKGYLPETETDFIFSIITEELGLIG
                     ALCVLFLLFSLCMRIFCLSSRCKNQQAGLFLLGFGTLLFVQTIMNVGSIAGLMPMTGV
                     PLPFVSYGGTSYLILSLGIGITLNISSKIQAEELALYRPEKQ"
     gene            15139..15894
                     /locus_tag="LLC22_001117"
     CDS             15139..15894
                     /locus_tag="LLC22_001117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5434409.1"
                     /translation="MKVSQKIILSILLLLTLVVGYFSIEFIHGFSSAKQSSTVKKVEP
                     KSIPTTLNVALIGSDARSKDENGRSDSLLVAQYNQKTQQAKLISIMRDSYVDIPGYGM
                     NKINAAYSYGGVDLLNQTLKENFKFEAPYYASITFQDFIDCVNELFPGGVKIDAEKSL
                     DLDGVYINKGEQVMDGNTLLQYARFREDKEGDFGRIRRQQQVIKAISQQLKDVTSIFK
                     LPKAVGKLLGSIQTNLPESVLLDCGMDFLKDIC"
     gene            15952..17991
                     /locus_tag="LLC22_001118"
     CDS             15952..17991
                     /locus_tag="LLC22_001118"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding transpeptidase
                     domain-containing protein"
                     /protein_id="HBK5434410.1"
                     /translation="MKRSDKHGKNRTGAYIAGAVILIAAAGGGYFYYQHYQETQAVEA
                     GEKTVEQFVQALNKGDYNKAAEMTSKKAANKSALSEKEILDKYQNIYGAADVKGLQIS
                     NLKVDKKDDSTYSFSYKAKMNTSLGELKDLSYKGTLDRNDGQTTINWQPNLVFPEMEG
                     NDKVSLTTQEAARGNIIDRNGEPLATTGKLKQLGVVPSKLGDGGEKTANIKAIASSFD
                     LTEDAINQAISQSWVQPDYFVPLKIIDGATPELPAGATIQEVDGRYYPLGEAAAQLIG
                     YVGDITAEDIDKNPELSSNGKIGRSGLEMAFDKDLRGTTGGKLSITDADGVEKKVLIE
                     HEVQNGKDIKLTIDAKAQKTAFDSLGGKAGSTVATTPKTGDLLALASSPSYDPNKMTN
                     GISQEDYKAYEENPEHPFISRFATGYAPGSTFKMITAAIGLDNGTIDPNEVLTINGLK
                     WQKDSSWGSYQVTRVSSDVSQVDLKTALIYSDNIYAAQETLKMGEKKFRTGLDKFIFG
                     EDLDLPISMNPAQISNEDSFNSDILLADTGYGQGELLITPIQQAAMYSVFTNNGTLVY
                     PKLIADKETKDKKNVISETAVQTIVPDLREVVQDVNGTAHSLSALGIPLAAKTGTAEI
                     KEKQDVKGQENSFLFAFNLDNQGYMMVSMLENKEDDDSATKRASELLQYLNQNYQ"
     gene            complement(18100..19251)
                     /locus_tag="LLC22_001119"
     CDS             complement(18100..19251)
                     /locus_tag="LLC22_001119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation:proton antiporter"
                     /protein_id="HBK5434411.1"
                     /translation="MEFIGILCLILISTTIGSHISRRLGIPAVIGQLLVGVLLGQAGL
                     NWVKPDILVHDFSEIGVILLMFLAGLESDLSLLKKYFRPGMFVALLGIIFPVVFGWLT
                     GKAFQVSGNEAIFFGIILAATSVSISVEVLKELNVVNTKEGSTILGASVVDDILVVLV
                     LSFSLSFLTGEASSNASLPLVLIEQLIYFVFIFLLVKWIAPFLLSFAEKVYANSSIII
                     VSLVICLGMSYVADLVGLSSVIGAFFAGIAVSQTKVKEEVYHNVEALGYAVFIPVFFV
                     SVGLEVDFSDFSEQLLFISILTLVAILTKLLGGYFGAQIAGFSQHSSLMVGAGMISRG
                     EMALIILQIGQQSQLIEPQYYSPLVIVILLSTLISPLVLKYFTKKVYEV"
     gene            complement(19405..19935)
                     /locus_tag="LLC22_001120"
     CDS             complement(19405..19935)
                     /locus_tag="LLC22_001120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF308 domain-containing protein"
                     /protein_id="HBK5434412.1"
                     /translation="MFETIKQNIQKYALLRAAVYIISGIAIVLNPSAVFHFIGYLITA
                     YLVLLGLLNLFEAYRFKRKTGSWSIGLFSGLFFLILALIVYAFAPAIVSILPILLGLA
                     VIINSLFQLFFSMNTKAKSWSVYSSILLLIGGFVLLFNPFKSLMLLFQIFGFILIFMG
                     IQEIINFIRIRKMTIR"
     gene            complement(20034..20384)
                     /locus_tag="LLC22_001121"
     CDS             complement(20034..20384)
                     /locus_tag="LLC22_001121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2200 domain-containing protein"
                     /protein_id="HBK5434413.1"
                     /translation="MAQNRIFTTSFASVYPMYVAKAERKDRIKEEVDEIICWLTGYSQ
                     TELEYQLQKQVTFEQFFAEAPVPNPSRSLITGVVCGVRVEDIEDNLMKEIRYLDKMID
                     ELAKGKKMEKILRS"
     gene            complement(20541..22070)
                     /gene="ahpF"
                     /locus_tag="LLC22_001122"
     CDS             complement(20541..22070)
                     /gene="ahpF"
                     /locus_tag="LLC22_001122"
                     /EC_number="1.8.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkyl hydroperoxide reductase subunit F"
                     /protein_id="HBK5434414.1"
                     /translation="MLDKETKQNLEQYLALIESPIVFSVSLDNSENSQKLAEFTKEIA
                     EMSPKISWEKRDSMRTPSFSINPVGKESGIVFAGIPLGHEFSSFLLAMLQISGRAPKI
                     SESLSLKIKKITQTLHFDSYVSLTCHNCPDVVQALNILAVLNPNITHTMIEGGMFQKE
                     IDDKKIMAVPTVFLNGEEFSSGRMTIEQIVEKITGPLIEEELFEKEPYDVLVIGGGPA
                     ASSAAIYAARKGIRTGLVADSFGGQVVETLGIENMIGTSYTEGPKLMQQVESHVRSYP
                     IDIMMNQQAVSLNKEQHFINIGLANGISLKAKTAIIATGAHWRSINVPGEKEFKNKGI
                     AYCPHCDGPLFKGKEIAVIGGGNSGVEAAIDLAGLAKHVYVLEFLPELKADQILQDKL
                     VSLANVTVIKHAATKEISGTNQVESLSYIDRRTMEMHTLAVSGVFILVGLLPNTDWLD
                     GTIEMNPRNEIVTEKNGATNIPGVFAAGDCTDSPYKQIIVSMGSGATAALGAFDYLMR
                     T"
     gene            complement(22080..22643)
                     /gene="ahpC"
                     /locus_tag="LLC22_001123"
     CDS             complement(22080..22643)
                     /gene="ahpC"
                     /locus_tag="LLC22_001123"
                     /EC_number="1.11.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peroxiredoxin"
                     /protein_id="HBK5434415.1"
                     /translation="MSLIGKKIEEFNAHAYHQGEFLEVSEKDLMGNWSILCFYPADFT
                     FVCPTELEDLQEQYSTLKSLGVEVFSCSTDTHFTHKAWHDTSDAIGKIEYVMIGDPSH
                     QISRIFDVLDEEQGLAQRGTFIIDPDGIVQAMEINADGIGRDASALIDKIRAAQYVRT
                     HPGEVCPAKWKESGETLKPSFDLVGKI"
     gene            complement(22787..23449)
                     /locus_tag="LLC22_001124"
     CDS             complement(22787..23449)
                     /locus_tag="LLC22_001124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5434416.1"
                     /translation="MKSSLQSQAYQAIRKQIIYADLEPGRKISEKALEEHLAIGRTPI
                     REALIQLRQQELVYTIPQSGTYVSKINLVSAENARFVREQLEEQIMIECCSKLDTQTR
                     IVLETILEEQEKAVKINDERAFFRADNLFHEACFEIAGRKEVWNWLDDHNTHLERFRW
                     LRVTIQGLPWETIMEQHYDLLKALVDKKPEEARFQTGLHLHMMLKEQETVTQRYPEYF
                     QQ"
     gene            23633..25279
                     /locus_tag="LLC22_001125"
     CDS             23633..25279
                     /locus_tag="LLC22_001125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol dehydrogenase family protein"
                     /protein_id="HBK5434417.1"
                     /translation="MIDLNNWRNFIPELSQKEVEIPHFDRASLRENGQKNPVWIHFGG
                     GNLYRGFHAEIAQRLADLGELSTGVIVCETFDEEIIERAYQDFDDLILEVVMPSSGEF
                     VKRILAATADSLYCHPDCSEHFDKMIRHFENPSLQLVTFAITEKGYRLKDTNNKYIGP
                     IAVDIKNGPKKPSHTMSILAVLLYKRFLSGAWPIALVSTDNFSQNGSQLRTSLLTIAK
                     EWQKEGYVQNTFIQYLSNEEIVAFPWTMIDRITPNPSLSVSKMLAKEGFSNMSIFQTA
                     KGNNIAPFVNTEDIHYLIMEDHFPNGRPKFEKAGVFLTDRATVDKADTMKVTTCLNPL
                     HTSLAIMGCLLGYRSIAEEMKDPDLSLLVSEIGYNEGLPVVESPGIIDPKIFLEEVIT
                     VRFSNPNIPNMPQRIATDTSQKVAIRYGETIKKYMEIEVKDPQTLVFIPLTLAAWLRY
                     LIGIDDQGKPFIPSPDPLLTDLQHKLSDIQLGTQDTSHIHEKMAPILSNKEIFGVDLY
                     QAELGRKIEEMFIKMVAGPNAVRKTLQDYLQEHGGNLSWK"
     gene            25270..26352
                     /gene="uxuA"
                     /locus_tag="LLC22_001126"
     CDS             25270..26352
                     /gene="uxuA"
                     /locus_tag="LLC22_001126"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBK5434418.1"
                     /translation="MEMTFRWYGSQEEKITLDEIRQIPAVKGIVGTLMDIPVGEVWPR
                     ERIKELKEEIESRGLTLKVIESVNVHDAIKIGLPSREQYIENYKQTIRNLAEYGIEVI
                     CYNFMPVFDWVKSDLDYRLEDGSSTLAFISDDIPDDPREIVARIEHSSNEFGLPGWEP
                     ERLAPIKSLLEAYASVDEEKLRENFAYFLQSIIPTCEEVGVKMAVHPDDPPYSIFGLA
                     RIVKNREDLDWLCRIVDSPYNGITLCTGSIAEDPENDVYGILAEFCQRDRIPFAHVRN
                     IKFLANRDFYEAPHKSEYGSLDMYRILKTMYDNGFNGYIRPDHGRMIWNETGRPGYGL
                     YDRALGAVYLNGLWEAIEKGNKSKDN"
     gene            complement(26460..28013)
                     /locus_tag="LLC22_001127"
                     /pseudo
     CDS             complement(26460..28013)
                     /locus_tag="LLC22_001127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738699.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            28161..29302
                     /locus_tag="LLC22_001128"
                     /pseudo
     CDS             28161..29302
                     /locus_tag="LLC22_001128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318369.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
     gene            complement(29428..30507)
                     /locus_tag="LLC22_001129"
     CDS             complement(29428..30507)
                     /locus_tag="LLC22_001129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5434419.1"
                     /translation="MNNVFIFCYLEVVDLTVYQRFLANEKIRRLTVLLFVVFVLFLVR
                     SMITTILLTFIFTYLMIHLVQIIQRFVRIPTGVLAIMIYTLIVYLIYLAFTKYIPMLI
                     HQTFDMIQSVINFYEHQPKDADPVLQYIHTYIERNDFFEQLQNGASIALGYLQDIGKM
                     AVAFAMSFILSFFFMIEKKKTIVFSRLFLKSEFSWFFQDIYYFADKFVNTFGLVLEAQ
                     FVVALLNTLLTTIALAVFGFHQLLSLAIMIFILSLIPVAGVIISCIPLSFIAYSQGGI
                     RDVVYILITILIVHLIESYVLNPKLMSSKTELPIFYTFVVLLVSERFFGVWGLIVGIP
                     IFTFFLDVLKVKKIPNHLPKETDIP"
     gene            complement(30610..31050)
                     /locus_tag="LLC22_001130"
     CDS             complement(30610..31050)
                     /locus_tag="LLC22_001130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5434420.1"
                     /translation="MEDLYLVNQVCFPLYAASKEIIRHYTPLLKPLNLTYTQYLVMLV
                     LWEKKKTSVKELGNDLCLDSGTLTPLLKKLAEKNYINRQRETGDERIVNVTLTAQGAA
                     LQKQAEGIPQKIKSYLPLEQEELDTLQHLTRKMLDNFHQDQKKG"
     gene            complement(31107..31517)
                     /locus_tag="LLC22_001131"
     CDS             complement(31107..31517)
                     /locus_tag="LLC22_001131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="organic hydroperoxide resistance protein"
                     /protein_id="HBK5434421.1"
                     /translation="MKKMYSTKMINTGGRSGEVHNPDRTFELNIAAHGKRVENATNPE
                     QLFAAGFSACFNSALELIKQQKNISGASTVSAQVSLYSESETSFVLGVEIEGSIEGLS
                     LEETQELLEAAHKVCPYSKATAGNIEVTLKAVSE"
     gene            complement(31697..32131)
                     /locus_tag="LLC22_001132"
     CDS             complement(31697..32131)
                     /locus_tag="LLC22_001132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5434422.1"
                     /translation="MHKGTEIDFVLNDSLKALELYQTIFDEIQLIEATDYPRGNNEVI
                     FTLYGTRFHMLDENTSLGLTAPTAEHPNTIWFNIIVSDIEDTHNKALRNGCVEIQEMT
                     EMMDFGVTNSMFRDPFGYLWMLHQVHREVIFEERKQLFEKYM"
     gene            complement(32231..33079)
                     /locus_tag="LLC22_001133"
     CDS             complement(32231..33079)
                     /locus_tag="LLC22_001133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5434423.1"
                     /translation="MKETRQFIWTYIKIIFALFILGVAINMFLGPHHIAAGGVSGLGI
                     LLEAALGFDRAIVILVLNIVMLVLALLFLGKKPFFKVLFGSLVFPLIIAIVPETMITS
                     DRLLSVIFGSAIFALGVAILYKNNSSSGGTTIPPLIFKKYFHLNTSIGLFFTDAFVVS
                     LNLFIFGIEEFLYAILSIAITSIVMTYIETGINRKKSVMVMSEHYLEDIRLRLSAEIG
                     RGLTLLEAKGGYNRKSKEVLLIVVTDHEFSRMKPLIEEIDPSAFVIVSSVAEVMGRGF
                     TYHPIE"
     gene            33468..35234
                     /locus_tag="LLC22_001134"
     CDS             33468..35234
                     /locus_tag="LLC22_001134"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008271692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glycosidase"
                     /protein_id="HBK5434424.1"
                     /translation="MDTAAIYHRPESEYAFLYTNTRFRIRLRTRKNDIKKVYVLCGDP
                     YTITTEKWYQKQRPMKKCLSTNVHDYWEIEVTSETSRLQYAFHVVGEDNTDCFYGDQG
                     IFPYRENVITEPNFYFRIPYFHQIDRFTIPEWVKETVWYQIFPERFANGDKANDPEHT
                     LPWGSKDPDREDFFGGDLQGVMDHLDYLTDLGINGIYFCPIFKATSNHKYDTIDYYEV
                     DPAFGDKKLLKNLIDEAHKRGIRIMFDAVFNHMGVHSPQWQDVLKNGEKSIYKDWFHI
                     RFFPVDSYQMTDLPETAENIPYDTFAFTPFMPKLNTANPEVQKYLLDIATYWIKEFDI
                     DGWRLDVANEVDHHFWKKFREAVTEIKPDIYILGEIWHSSQAWLQGDEFHAVMNYAFT
                     DSIKDYFAKKKITASQMVSGMNHQQMLYRDQVNEGTFNLLDSHDTARILTLCQGNKEL
                     MKSVMAFMFLQKGSPCIYYGTEIGMTGEDDPDCRKCMIWEKEEQDLELFGFIKELVSL
                     RKQLSKIISEGSTQWLIVNDREDKLYFTRKLEGQIIYVYFNQSKEPWVVEQENEVILS
                     QNCQLLEDGKAEIRQYGFLIMC"
     gene            35336..36595
                     /locus_tag="LLC22_001135"
     CDS             35336..36595
                     /locus_tag="LLC22_001135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5434425.1"
                     /translation="MKKRSVKQLGLGLISLGILGGLAACGNGNSSAEGEADEGKTLTV
                     SVDSGYKDYINEIKNTFEKENDVKIKLVEKDMFDQLESLALDGPAGKGPDVMMAAYDR
                     IGALGQQGHLAEVKLGNEAAYDETDKAQVTYDGKIYGEPAVIETLVLYYNKDLVDTAP
                     STFKDLENLSKDSRFAFESEAGKNTGFLAKWTDFYYSYGLIAGYGGYVFGDDGTNPSD
                     IGLNNAGAVEGISYATDWFKNVWPKGMQDIKSAGDFASQQFMSNKTAAIIDGPWQAQT
                     YKENNINYGVAKIPTLNNGQPYQPFGGGKGWVVSNYAKNKDLSQKWLDYVTNQENQEK
                     FFEMVNEIPANQQARETAKAKNDELTTAVIEQYETAQAMPNIPEMGEVWTGAENLMFD
                     AASGSKTPKESADEAVKTISEAIEQKY"
     gene            36742..38043
                     /locus_tag="LLC22_001136"
     CDS             36742..38043
                     /locus_tag="LLC22_001136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5434426.1"
                     /translation="MQQDKTSNINEKKITLCSLIPGMGQFVNGQAFKGIVFFAIFVLF
                     IGQMLLGGFHALVGLVTLGSIPMEDHSLFILIEGTLQFIITIIFLIFYGLNLLDAYRV
                     AKMRQEGKKINRTMKEVIHNIGDEGFPYLLTLPAYLLMIFTIIFPVLVTLFTAFTNYD
                     FNHIPPASLIDWVGAKNFFSIFFLSSYRNTFFAVFSWTVIWTLCATTLQITLGILTAV
                     VAHQKFIKFKRIFGIIFLLPWAVPAFITIMSFSNIFNDSVGAINTQVIPFINQLPFVD
                     ISAISWKTDPNWTKVAIILVQGWLGFPYIYVMVTGILQSISEDLYEAAKIDGANAWQR
                     FSNITLPAVFLVAAPTFITQYTGNFNNFSMIYLFNNGGPGSVGGGAGSTDILISWIYK
                     LTTGTSQQYSMASAITLIISVIVICVSLLVFKKTNAFNMGD"
     gene            38046..38897
                     /locus_tag="LLC22_001137"
     CDS             38046..38897
                     /locus_tag="LLC22_001137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5434427.1"
                     /translation="MKKFHSSARFQKRLSHFFTYFFLLILSVIIIYPLLITASTAFKS
                     GNIAAFSLDLSSDWTLGNFTRLFSETLYGTWYKNTLIISVLTMIVQVTVVTLAGYTYS
                     RYRFIGRKSSLMFFLVIQMVPTMAALTAFYVMAFLLEALDKYWFLTMIYIGGGIPMNT
                     WLMKGYFDTVPIDLDESAKLDGAGHFRIFFQIVLPLVKPMLAVQALWAFMGPFGDFML
                     AKFLLRTPENQTVAVGLQTFISDVTNQRVSLFAAGAILIALPICLLFFFLQKNFVTGL
                     TSGGTKG"
     gene            38910..39725
                     /locus_tag="LLC22_001138"
     CDS             38910..39725
                     /locus_tag="LLC22_001138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltodextrose utilization protein MalA"
                     /protein_id="HBK5434428.1"
                     /translation="MQTFPLNYFSALRTPTQVFAGRKLLSWPKFFLIFVFLVSLMVMP
                     VTLFYANQIQAIPLEQFLSVHSLIDEQGTQKFSELELSETGLQASQQTIAVTPEILVG
                     VSLSEKQQSDHGTFIDFEKEQWVIQQKDKSGIRRYTMNYSPSFQPDSVRTPEDFQRFL
                     EREFYASNRPTIILSYSLSLGLVLFVMTSLILFGASFFLWMTRKSQLSSIHTFKESAN
                     LMLNVMGIGSMAAAVVGFIHFDFILMLSVQTTITVLLLLWVFVKTRFKDKRVE"
     gene            39876..41042
                     /locus_tag="LLC22_001139"
     CDS             39876..41042
                     /locus_tag="LLC22_001139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369828.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5434429.1"
                     /translation="MLEKTLYNQLFSRSFSLPVEVNYWDGTTKQYGDTDTPPQIKINI
                     HEEIPMKEITSNASLALGEAYMDHRIEIEGSIQALINDAYQQANSFLRGKDYLKWLPK
                     KEKHTKQKNKEDIHAHYDLGNDFYKLWLDPTLTYSCAYFNTPEDTLEQAQINKVHHIL
                     DKLFIKEGETLLDIGCGWGTLMFTATKEYNVKATGITLSEEQYDLITKRIKEEHLEDK
                     CRVLLMDYRELKGETFDHITSVGMFEHVGSENLEGYFKVVKDLLKPKGTALIHGISRQ
                     QGGATNAWINKYIFPGGYVPGVTELVDNITKNDLQLIDLESLRRDYQLTLEHWTKNFH
                     QVQDQVTKEMGDSFYRMWDLYLQACAASFESSNIDVIQYLLVQPGNNDIPMHRA"
BASE COUNT        13972 a         7119 c         7989 g        12072 t
ORIGIN      
        1 aaataagaaa ttgattgtcg ttttcttttg cagaaattta agtgcaggca attatggtag
       61 ttgtcgtaat tgctgtcagc tcagtgttta tcactgatgg tgtgaaagat ttacggttgg
      121 agatgttcaa taagattatt ggtgcttaat tatttttatt gtagtgctga tatgagaatg
      181 ttataattgg ggtataaaac atacaaataa atttgctgaa aaatgaggta tcaaaatatg
      241 gaaaatgaat tactggaaaa cttaggaaga cttcacacaa ctgaacttgg cgttattaga
      301 attaaaaaga acttatcttt gaatgtagaa aatgtaattg aatggtgcaa agaaaaaatt
      361 agcctttcta atgcggaaat cacaagaaaa ggaaaaaact ggtatataac gattgataat
      421 tgtattataa cggtaaatgc gtacagttat accgttatca ctgctcacaa ggtaaaatga
      481 taaatttttc tataaaggaa ttaaacgcat ttgcagttat tgggcaggaa gtagaactga
      541 ctaattatca aaaaaagaat attcagatta gtacacagtt ttggagaaag tttaacagta
      601 gtttgaaaaa agcgtatctt tcacaatcag gaaattgggt aaaatatgct tttatggaaa
      661 gaagaaatgg aaaactttat tatttctgtt ctattcccca aagaaccatt accccagagg
      721 gctttctgta taaagaaata ccgtcttata aatatttggt tgtggagcat attggtgcta
      781 tggataaaat atatgaaact tatggcaaga tttatgaaga aattattcct agtacatcgt
      841 atattcctat aaaagatatt atcctacact ttgaaaaata cgattatcgt tttcattgga
      901 atagtgataa ttcagttatt gaaatttgga tacctattca agattagaag caattttata
      961 tccatacaca caaagcagtt agtcttagga ttgactgctt tttctataca gatttttaat
     1021 gacaggcaat tatcaattat ggtagttgcc ttttttgatt ggaggaattg aagaatgaat
     1081 gataaaaact ttattgaaga actaagacaa aagcgtgagg aatacggagt aacacaaaca
     1141 aggcttgctg ttgcctgtgg tatcagccgt gaatattaca accgcattga aaaaggaaaa
     1201 cagccattga atgacgaatt aagagaaatc atagaaaaac agattgagcg tttcaatccg
     1261 caagaaccac tattcttatt gattgattac tttcgtgtcc gctttcctac tacggacgca
     1321 ttggcgatta tccgtgatgt attacaactg aaatctaatt acatgcttta tgaagattat
     1381 ggaaaatacg gatatgaaag caaatatgta cttggcgaca tcaatatcat gtgttccatg
     1441 caggagcatt taggtgtttt attggaactg aaaggcaaag gctgtcggca aatggaatgt
     1501 tatctgctgg cacaggaacg ctcatggtat gacttcatgc tggattgtat gacggctggt
     1561 ggtgtgatga aacggcttga tttggctatc aatgataaag caggaatatt ggatattcca
     1621 aagttaaagg aaaaatacaa ggctggcgaa tgtatgtcct acttccgtat gcagaaagat
     1681 tacagcggta cagaaaaatg cggtagcgat ttaccaaaga atacaggaga aaccttatat
     1741 ctcggttcaa caagtagcga attatatatg tgtgcttatc agaaaaatta tgagcagtat
     1801 gtcaagaatg gcacagaaat tgaagatacg gagattaaga accgttttga aatacgcatg
     1861 aagaacgaac gagcctatta tgcggttgta gatttactga cctatcggga cgctgaacgc
     1921 accgcttttt ctatcatcaa tcattatgtc cgctttgttg acagagagga cgacaagcca
     1981 aaaagtcaat ggataacaaa tgatgattgg gcatggtttg taggggaaaa cagagagccg
     2041 atacgcttaa ccacaaagcc agagccttac actttacaaa aagcgttgca ttggctacaa
     2101 agacaagtcg caccaaccat aaaaatggta caggcattag acagagaaaa tcgtacaacg
     2161 atactgaaag atatgattga gcaggcagaa ctaaaagaca agcataaaca tttattacaa
     2221 ttagagaaat caaccataga agaacgtata gataccgctg ttccacaaga gaatgacggt
     2281 attttttaat gtaattgaaa aatttcagat ttagtcagca aagagctgtt ttcattccct
     2341 atgtgaagtg aaagaagaaa aataaatttt ttattaaatc tgcaacaaaa tggctacttg
     2401 cgtacagata tggtgcgaga aaaggaaatc taaacttttt ttgaaaatag gtcattaaat
     2461 cggggcttgc tgtccctata tgaagtgaaa gaagaaaaaa gttttgaaaa aatgacggaa
     2521 attcgtgatt agtggacagt cttctgtgaa aagaggaaaa acatcatcat tttgtattca
     2581 aacaggcatt agcagttgag tgttgatgtg aaaagatgaa aatactttgt tctcaactta
     2641 acaatttaag gtttccgttc cctatatggt gcaaagaaaa tatttcattc tattgttggc
     2701 agtaacggta tggtttgggt agttagggtg tgaaaaggaa aatattcttt tttcatcatc
     2761 aacttagcaa aatgacattt tctatcccta tatggtgcat gaaaagaagt taaaattttt
     2821 ccatttaaac ttagcaaatg gacgtttgct gtacagatag tagtgaaaaa ggagaaaatc
     2881 aaccgttgat tgccaaaatg aaccgttcca tttgtactaa taatggaaaa agttttggat
     2941 tttggttacg tttctcctct tttccaacgc gatatatagg aaagacgatt tttttctttc
     3001 aatcgttctt tgacaactga ataaagctat tcaatacgtt tgacagacag ctagccgttg
     3061 aaacaaatac gccacgacct ttcccctgca agagcgagcg aaaacctatt tgtgttcttg
     3121 taaaagattt gtcctctttt atcgccatga cctgtactgt cagataatga tactcccgta
     3181 cagccacagc ttgagcatta agagcgtcgc acgcaatggg tacggctaca taagaactat
     3241 gcagaggtgg aactcctgtg ggctatgaca aaagccgttg aattgcttag aaagatttta
     3301 cagaaagggg gtatgtgtta ttgataatgc tgtaaaaaca attcaaaaga aaaatggcaa
     3361 gtgtggcatt ggcaacagag gaaagacaaa gattgtagta aaagagcatt tttccgaaaa
     3421 gggcaaaaca atggaagaac ttctaactga tgtcatgctg gaaaaagcaa agcagacaat
     3481 cgcataaaat cggtgcagtt gtaagaaata gattgaatga caaaaagtac ccgtgttata
     3541 ctttacttgc aagcaggtat tgtaaacacg ggttagttat aaaggaggat aactgacaat
     3601 gaaacaacag atttacaata ctgcacttta tcttaggtta agccgagatg atgaattaca
     3661 gggcgaaagt tccagcatta ccacacagag aagtatgttg cgtttatatg caaaagaaca
     3721 tcatttgaat gtcattgatg aatatattga tgacggctgg tcgggaacaa attttgacag
     3781 accgagtttt caaagaatga ttgaggatat agaggcagga aaaatcaact gtgttgtaac
     3841 gaaagacctt tcccgtcttg gcagaaatta tattatgaca ggacaatata cagaattgta
     3901 tttccctagt cataatgtcc gctacatagc gattgatgac ggtgtagaca gcgaaaaagg
     3961 cgaaagtgag attgcaccat ttaagaacat catcaatgaa tgggtggcaa gagatacaag
     4021 ccgtaaagtc aaatcagcat ttaagacaaa gtttgcggag ggggctcatt acggtgctta
     4081 tgctccgtta ggatataaga aacaccctga catcaaagga aaactgttgg ttgatgatga
     4141 aacaaaatgg attattgaaa aaatcttttc cctagcctat caaggttacg gaagtgcaaa
     4201 aatcacaaag cagttaagag cagaaaaagt tccgacagcg tcatggctaa attttacaag
     4261 atacggtact tttgcacata tctttgaggg aaaacccgaa agtaagcgtt atgagtggac
     4321 gattgctcat gtcaaggcga tattgaaaag tgaggtttat atcggaaaca gtgttcacaa
     4381 tatgcagtct acggtatcgt tcaagagcaa aaagaaagtg cgtaagcccg aaagtgaatg
     4441 gtttcgagta gaaaacactc acgagccgat tattgacaag gaagtgttct atcgtgtgca
     4501 ggagcagata aaatcaagac gcagacagac aaaggaaaag gcaacgccga tttttgcagg
     4561 gcttgtcaag tgtgcggatt gtggttggtc tatgagattt ggaacgaata agacaaataa
     4621 aacgccttac agttattatg cttgcagtta ctacgggcag tttggcaaag gtaattgttc
     4681 tatgcactac attcgttatg atgtgctgta tcaagccgta ttggaacgct tgcagtattg
     4741 ggctaaggca gtacagcagg acgaagaaaa ggtattgaac aagatacaga aagctggcaa
     4801 tgcagagaga atacgggaaa agaagaaaaa ggcaagtaca ttgaagaaag ccgagaacag
     4861 acaaaatgag attgaccgtt tatttgcgaa aatgtatgaa gatagagcct gtgagaagat
     4921 aacagagcga aattttgtga tgttgtccag caagtaccaa aaagaacaga tagaactgga
     4981 acagcagata acaagcctaa gagaagaact aagtaaaatg gaacaggata tgataggtgc
     5041 tgaaaagtgg attgagttaa tcaaggaata ttccgtacca aaggaactga cagcaccatt
     5101 attaaatgcc atgatagaaa aaatcctcat acatgaagca acaacgaatg aggataacga
     5161 aagaatacag gaaattgaga tatattaccg atttattgga agagttgagt aatcaacaag
     5221 agtaatattt ttaactaagg gaaaccggcg gtgtctatac ttgggtcagt cgcacattgg
     5281 gaaaacgatt cggttttgcc gcaatctttt tccaatggtt tgagataaca gttggctact
     5341 tgaccatgct gtatttctta actggtgcat tatcctatgc aacgggtatt ggtgctatac
     5401 aaaacaataa atatctgaaa ttggcaatcc tattgattat tttctgggct attttactct
     5461 cacagttaaa aggaaccaaa tacacttcat tgattgctcg gatcggtttt gtagctggta
     5521 tcttgttgcc agcattagtc ttgtttggct tagggatcca ttatgtcgct tcaggcgctc
     5581 cactacaaac gatactgtct atgaaaacat tgattcctga tttttcgaaa ttgcctacgc
     5641 tggttgtttt tgtttccttt attttagcat atatgggcgt agaaacatct gccagtcatg
     5701 caaatgaaat ggaaaaccct aaaaaggatt atccattagc aatgtttgta ttggttattc
     5761 tggcaatcat tttagatact tttggcggat tgaccgtcgc tactacagta cctcaacatg
     5821 gtttgtctct taatacaggg gtgattcaat cgttagaatt cctattaaga cacattgatc
     5881 caaatcttgc atggattgcg aaaattcttg cgattcttgt ttgtttaggt gtcatcggag
     5941 aaattgcttc ttgggtaacc tctccttcaa aagcacttca cgtagcagca gaagaaggat
     6001 tacttcctga atattttgca aaagaaaaca cacacggtgt tcctgctcat ttgatgatcg
     6061 caaatgggat cgttgcaaca atctgggcag ccgtctttac attaagcggc ggggggaata
     6121 atctttcatt tcttgcagcg atgtcattga ctgttgtaat ctacctgatg ttgtacttta
     6181 tgtttttcgc gggctatttg aagctggttt ttaaagatga cagtcttgaa agagcctatc
     6241 aggttccagg cggaaaagtt gtaaaagtaa tcgttgcttg tttaggtctt ttgacttcac
     6301 tttttgcttt ttgtatctca tttgttccac ctgctagtat cgcagctgga cagcatggga
     6361 tttatgaaac gattctgatt gtttcttatc ttatcgtctt agttattcca tttacgatct
     6421 acgcatgccg tcataaattc cagcatgcag aaaaataaaa aatgaaagct ggttattcaa
     6481 atggaagtaa aagaattaga acaattgatt ggaaaaaatt tccactatta tcaaacagga
     6541 caagtggcgg attacattcc agcattagct gaagtggatc ccaaacaatt aggtatggcg
     6601 atttatgatt tggatacaaa acaactgatt gagggaggag acgccgatgt gcgctttgcc
     6661 atcgaaagca tgtcaaaagt tcccgtattg ttattagcaa tcaaagacaa cggaatagaa
     6721 aaagtctttc aaacaatcaa cacggaacca accggttttg ccttcaattc tatcatgaat
     6781 atggaaatca atcatcgcaa acatccaatg aatccttttg ttaatgcagg agcgattgca
     6841 acaacctcgt tgattgccgg taaagatgca gatgaaaaat ttgagcgaat cttgtcattt
     6901 atgaaagaga tctgtgatga tcctaatatc acattgaatg aagaaatcta tcattctgaa
     6961 tcaagaacag gtgatatcaa tcgctctctt gcttactata tgaaaggtaa tcaaatgatc
     7021 gaaggagacg taccggagat actcgatgct tatttcagac aatgctccct caatgtcacc
     7081 gctacaggca tagcaaaatt agctgctgtg ctggcaaata aaggaattgc tccttggaat
     7141 ggcaaacaaa tcattactga agaaagtgct acaatcgtca aatcaattat gacaactgct
     7201 ggtttgtatg atgaatcagg agagttttcc gtccatgttg gtgtacctgc aaaaagcggt
     7261 gtaggcggcg ggttgatggc agctgtgcca aatcgttacg gcataggtgt cttcagcccg
     7321 gcactagatc catttggtaa cagcgcagct ggtatccaat tgttgaaaga tgtagtcaaa
     7381 gaactagacg ctgacatctt tgaataacca ttcttgaaag aggctggggt aaaagtccaa
     7441 acggctcaaa gctacctaca atgaggctga aattgtgagc ttgtttgact tttgtcccag
     7501 tttctttttt tattggtttt tgaaagggct tttctaaata aaaaggaaac aaaaatacga
     7561 tttacagata tgattaaata aaatcataag aaaaactgga ggcgtgtatc aggaatgctg
     7621 gaaaattaca tcgagcgaaa tatatttaga aaagtgtatc tgtgtgaaca attatttgaa
     7681 ttccaagaaa tagacatcga acaaacagct atttctctaa gggtgactac accaacgatc
     7741 cttcacgatc tagaaagtct agccgagtgt ctagaatatt gtataaaaga acaagtaaga
     7801 gagaagcata agtataaact cgtattcaaa catggtattg ctctttctga gctcacacag
     7861 tttctgtacg gtcaatctta ttttttaaag tttttaagtt attattttaa tggtatattc
     7921 acgagtacag aactggctga tcttgaattt atttctttga gtaaagtata tacaatcaaa
     7981 aaaatcgtat tggatttttt taaagaaaat gattatttga aaaataaaga aatcattatc
     8041 ccagaatttg actcgcggaa catcttgcta gctttagtac gttatgtcaa ttgggaaggc
     8101 tatgaaaata aaaatccgta tgtagaagaa gcttgtaacg agttgattga ttatgtagag
     8161 actcattttt ttaaaagaag atattcggaa gatgaaaagt cctttatcat acgagaaata
     8221 gagatcgcaa tcggaagaaa ggcatttccc cttggactga aagaagaaga taagaaaagc
     8281 gcagaaacga agccgttatt tcaattagtc tgtcaaggat tggaagagca aaaaggaatt
     8341 ctagacttac aagaagaaga tgtctattat attttttctt tgttcaacag tagaaattat
     8401 accaatgaga acatggagct gttaagaaaa gatttcgaag ttgtttataa aaattttgtt
     8461 ctcaatgacc tatcactgaa tgaattgatt ttacagatta ttagtatcgc tgaaatcgac
     8521 gatgcagaaa attttatttt caagcaatcc tttttacaat ttgtccgtac gttgtgggca
     8581 gatggacaag tatttttacc ggaaaggatc tatcttctat cagaaaaaga acaacttctg
     8641 tacggaaaaa ttgtagaaat attggaagag tggaaaaaga aaaatcaaat ccaactaaga
     8701 tggaatgaaa atttcattcg aaaattcgtc aaaagtcttt ctttgatcaa cagtgaacaa
     8761 gcggggagac aggaaataga aatttttgtt gtttcagaaa gttcagtcaa acaatttttt
     8821 tatcgaaccc aatttcattt gtatgcggaa gaaggcatcg ctgaaataaa tcctatttta
     8881 tttcgttcat tagaagaatt gcctgatgaa tgtctatgtg cgaaaaaaag agtggttttg
     8941 tgcgatgctg ctagctatca aaatggatta gaaactgaaa agacaaagat ctatccaatc
     9001 tcattaaaag gtgcaaacat ccatttgtat catattgctc aggaacttca cctattaaaa
     9061 aaacatattt cttgatgaga ccttaattag gagaccttct acaaagcttt ttaattgtct
     9121 gtagaaggtt tttatttgag tcctgattcg tgcgaagatc tacttatata acaagctttc
     9181 tctgaaattt ttttaaaatg ctattgactt agagtcaact ctaagtagta gaatagataa
     9241 agtgtaacaa atctattttc attaaaagaa gatagtacgg aggagagaat gtattatgag
     9301 tacagtatta catgtattgg atgcaatcaa tagccccgca gatgtcaaaa aattatctgt
     9361 tgaggaaatg aaacagttgg cagaagagat gcgccaaaaa atcttgcaaa aggacagcga
     9421 tgtaggtggg cacgttggtc cgaatctagg tgtagtagaa ttaacgattg cgtttcatta
     9481 tgtatttgat tcaccaaagg ataaaatcgt ttgggatgtt tcccatcagt cttatggtca
     9541 taagctttta actggtcgaa aaaatggttt tgaaaaagga cattaccgtg aagtgagcgg
     9601 atattccaac caacatgaaa gtaaacatga ctattttaca gtggggcaca catctacatc
     9661 tatcagctta gcaacaggtt tagctaaagc gagagatctg aagaaagaat caggaaatgt
     9721 ggtagcattt atcggtgacg gctccctaag tggtggctta gcttttgaag gattgaacaa
     9781 tggtggtgtt ttacaatcca atctaatcgt attagtaaac gataatgaga tgtctattga
     9841 tgagaatcat ggcagtttat ataaaaactt agctgagctt cgtcaaacca acggtaaaag
     9901 cagcaataac ctatttaaag caatgggatt tgattatcgt tacgtggata atggaaacga
     9961 tctggaaacg gtgatccgtt tatttgaaga agtaaaagat attgatcatc cgattgtact
    10021 tcacgtccat acggaaaaag gtcgcggtta tcagccggca atcgataata aaatgaaata
    10081 tcattggcat gtaccatttg atctgtccac cggggaggca aagcaagtaa cttctggaga
    10141 aacatttaat atgatcatca tggattattt ggataagaaa atgcaaacaa gtacagctcc
    10201 tattgccgca gtcaatgcag cgataccagg cgcctttgga ctgaaaacat tccaagaaaa
    10261 acatccagat cattattttg acgtggggat cgctgaacag cactctatca ctttcgcttc
    10321 tgctttggct tctcagggag tacgtccagt cgtcttccaa tcaagtactt tcttgcaacg
    10381 ggcatatgat caattatcac atgatttagc gatcaacgag aatccagtga ttattttagt
    10441 cggtggcgga acgatctcag ctagtgaccg aacacaccaa ggaacatttg acattcctta
    10501 cttatcaagt atcccgaaca tcaaatatct tgctccagca acaaaagagg atatgatctc
    10561 tatgctagat tgggcgttcg aacaaacagc gcagcctgta gcaatccgaa ttcctacaca
    10621 tggtgtagaa catggtacag ctatcgcaaa tgattatagt attccagcct atcaaacagt
    10681 aaataatgga ggaaaagtag caattttagc tttaggcggt tttcttgaat taggaaaaga
    10741 aacagtaaaa gcttttagaa aaaaaggaat cgaagcaacg ttgatcaatc caggaacgat
    10801 cacagaaaat gacgtagaaa cattagataa attaaaagaa acacacgaat tagtcatcac
    10861 attagaagat ggtagtttgt caggaggatt tggcgaaaat atcagtcgtt attatggtga
    10921 ttcttcaatg aacgtattaa attttggtgc agagaaagaa ttcacggata gcgttcctgt
    10981 agggcagctt tatgaacgtt atcatttaac accaaaacaa atcgttgaag atagtctgcg
    11041 tgtcttgaat attcaataat tcattatgct caccatccag ataattgttt atactagtat
    11101 ctggatggtt ttttcattat aaaaagcaaa ggggtggatg ttatgtatca gcaagtagaa
    11161 gaatatgtca aaaagttcca agaaaaatat cctagttatc aatcagaaaa attaggtttc
    11221 ttttcatttg gggatacaga aaaaatggca gacgagttga gcgaactagt tgtaaaaaag
    11281 ataaagactg gtacatcaag tggttacgat ctgtataaac aagagaatga gcctttacca
    11341 aaagttggtc aattagacgt ggtcctgaat ggaaaaaatg aaccagtttg tatcatcaaa
    11401 aatataaatg tgaccatctt gccttttagt gaagtcacga aagagcatgc ttggaaagaa
    11461 ggagaagggg atcggacatt agcttattgg cggaaagtcc atgctgagtt ttttaaacat
    11521 gcttataaag aagcgttgaa catagaattt acagaagaga agctggtcgt atacgaagaa
    11581 tttgaagtaa ttttctttta gtaagaaagg tctgctgaaa gaaatagctc attattgtct
    11641 cctgaataga aaagggttac atttttatat gaagctgtat ttttatataa cattactgga
    11701 ggagatattg tggatacact ggaacaaatc aaaggcggag tcgtcgtttc ttgtcaagct
    11761 ttggaaaacg agccgctaca cagttctttt attatgggga gaatggcttt ggctgcaaaa
    11821 gaaggcggag cagttggtat tcgagcaaat acgacagaag atatcaatga aatcaagcga
    11881 atcgttgatt taccggtaat agggattatc aaaagagatt acgatgggtc agaagtgttt
    11941 attactgcga cagaaaaaga agtggaagaa cttttggaga cgcaagcaga aatcattgca
    12001 ctggatgcaa cttctcgtaa acgtccgaca gaaaaaacaa ctgctgaact tgtccaaatg
    12061 attcacgaac acggtcggtt agctatggca gatatttcga cttttgagga agcgcttcaa
    12121 gcgcaagaag atggttttga tcttttgtct acgactttag caggctatac agaatattca
    12181 cgaaagacgc agacacctga ttttgattta ttgaatcaaa tcatagaaca agtcgatatc
    12241 ccagtaatta tggaaggaca tactgactct cctgaacaag tagagaaagc atatgaatta
    12301 ggtgcttttt cagtcgtagt tggatctatt atcacccgtc cgcaattgat cactaaaaga
    12361 tatgtcgaag ccgcaagtaa agcaaataac taaaaaacac gcacggcaca gattcttgac
    12421 aaaaaagaaa aattgataga tagtttaaag cagattctaa gaagatgaaa aaagcattac
    12481 ttttcatttt gtcttcaaga tctgcttttt aacgaatttt atagaaagaa ggcgaaacca
    12541 tgtttgaacg gagtccttca gaattgacag aacgtgaaaa ttacaagttg ctgattggtt
    12601 cagtcatccc tagaccagta gcagtagtaa cgactaaatc agcaaaagat atagtgaata
    12661 tcgcaccctt cagttacttc aatatcgtca gttcgaatcg acccatctta tccttggcga
    12721 tccagagaaa acaagatgca gtaaaagaca cagcaaagaa tattcttgag acaagagaag
    12781 ctgttatcca tatccttgat gaggacaacg tagaagaagt aaataaaaca gcagccaatc
    12841 tgcctaatga ggaaagcgaa ctgtacctga ctgacttgac tttaactgat tcagtaatca
    12901 tttcagtacc agcattgaca gaagcaaaag ttcgttttga aacatcctta tatgaacatg
    12961 tcgagatacg gaataaaaat aaagtaacag ctgatttatt tttgctagaa gtacagaaat
    13021 atcatttaaa tgaaacagtc tatgatgata agacaggaag gatcgatcca agaaaattga
    13081 atgctgtaag ccgtttggca ggaaatgatt atgcagcaat aggagaaatt ttcacgattg
    13141 cacgtcccga ataaaaagga gcactagtta tgttaaaaat aagctataaa ccatcgacag
    13201 attcaaaaga aatgaaaaaa gaatatgaaa cagtgaatga ttttctgcaa gggcagtact
    13261 tagaagttcc gccattgcaa gaccattttg tcgttactac tgttacttta gatggtaagg
    13321 aaatagaaat gccagatcaa acgattagcg gattgtttaa ttactttaac aaataaatat
    13381 ttattccgaa aagtgaaaaa acatataaaa aaacacataa aactaaaaaa ttatcaaaga
    13441 atcctggtgc aactgaaaga atttgcaacg ggattctttc aacttatttg ttattttttt
    13501 ctaaaaaata ttaaagattg ttaaatttca ctatttcatt tcaaattcca ttgcctaatc
    13561 attaggaaaa gtctatcatg aactcgtaaa tagaatatag taataacctt gttaggtgag
    13621 gctcctatac aaacataggc tgttgcccag aaacgtcgaa agtcgccaat gggtaaaaca
    13681 gaaactgttg gattaaggct ttttccaata gctaagaatg ttttctttac gttgtatagt
    13741 gctaaaactc ggacgatgag atgatgctag gtcagaattc ttgttcgaaa aggtttctga
    13801 ccttttcttt atatttttgt gactgactta tttgatgaga caaactcgct cctcacctga
    13861 caagtggatt gctgtgtgag gaggagatgc ggtgaaaaaa gatcgattgg tggattttgg
    13921 gtccttattt gactttgtcc atgatcggtc ttttagaagt atacagtgcc agttcttatc
    13981 ttttattgca agccgatgaa aatacaaaaa gtctattatt gcgtcaacta attttcatat
    14041 ttttgagttg gagcgtgatc ttcttagctc gttcagtcaa actacactat ttacttcacc
    14101 ctaaaatagc aggatacggt ttagccttat cgattttctt tttagtatta gtaagaatag
    14161 ggatattcgg tgtcactgtc aacggcgcac aacgttggat ctctctgttt ggcattcaat
    14221 tccagccttc tgaactggca aatctttttt tgatttttta tttaagctgg ttttttcgtg
    14281 acggaaatag tagcccaaaa gatctaaaaa aaccattcct gattacagta ggtataactt
    14341 ttctgatttt atttcagcca aagattgctg gagcattgat gatcctttcg attgcgtggg
    14401 tcatattttg ggcagcggcg gttccattta aaaaagggat ctatctaatc gttacttttt
    14461 ctgcattgct gattggagca gcaggcgggg tattatattt aggaaataaa ggttggcttc
    14521 cacagatgtt taatcatgct tatgaaagga tcgcgacttt aagagattct tttatcgata
    14581 gtcatggtgc gggctatcaa atgacccatt cgttttatgc actatataat ggtggcatat
    14641 ttgggcgggg attaggaaat agtatcacaa aaaaagggta tcttccagag acagaaacag
    14701 attttatttt ttcgattatt acagaagagc ttgggctaat cggtgcattg tgtgtgcttt
    14761 tcttattgtt ctcattatgc atgagaatct tttgtttaag cagtcgctgt aaaaatcagc
    14821 aagctggatt gtttctttta ggattcggaa ctttgctatt cgttcagacg ataatgaacg
    14881 tgggaagtat cgcggggctg atgccaatga ctggtgtgcc attgccattt gttagctacg
    14941 gaggaacaag ttatctgatc ctttctttag gaatcggaat cacgttgaat atttcttcaa
    15001 agatacaggc cgaagagttg gcgctctatc gacctgaaaa acaataaaga gaaactgaga
    15061 aactctcagt ttgaattatc ataaagtaca atcttttatt tttcaagcga gaggttcttt
    15121 tagaaagagg aattcgcaat gaaagtatct caaaaaatca tattatctat tttgttactg
    15181 cttacattag tagttggcta tttttcgatt gagtttatcc atggattttc gtctgcaaaa
    15241 cagagttcaa ctgtgaaaaa ggtagagccg aaaagtatcc ctaccacact aaatgtggct
    15301 ttgattggtt cagatgctcg ttcgaaagac gaaaacggtc gctcggattc acttctggtt
    15361 gcacaataca accagaaaac acaacaagca aaactgatct ctatcatgag agattcatat
    15421 gtcgatattc caggttacgg aatgaataag ataaatgcag cttactctta tgggggagtt
    15481 gatttattaa atcaaacatt aaaggaaaat ttcaaatttg aagctcccta ttatgcaagt
    15541 atcacatttc aagattttat cgattgcgtt aatgaactgt ttcctggtgg agtcaagatc
    15601 gatgcagaaa aatctctaga tttagatggc gtatatataa acaaaggaga gcaagtgatg
    15661 gatggtaata ctttactcca gtatgctcga tttcgggaag acaaagaagg agacttcggg
    15721 aggatcagaa ggcagcagca agtgatcaaa gctatctctc agcagctgaa agacgtaact
    15781 tcaatattca agctacccaa agcggttggg aaattacttg gtagtatcca aacgaacctt
    15841 ccagaaagtg tgcttctgga ttgtggtatg gatttcctca aagacatatg ttagaataaa
    15901 caggtataaa tagtgaaata aaggaatgac aagcaagaga aggaggaaaa aatgaaaaga
    15961 agtgacaagc acggcaaaaa tcgaacaggc gcttatattg ccggcgcagt gatcttaata
    16021 gcagctgcgg gtggcggtta tttttactac cagcactatc aagaaaccca agcagtagaa
    16081 gctggagaaa agacagttga gcaatttgtc caagctttga acaagggaga ttataacaaa
    16141 gctgcagaaa tgacatcaaa aaaggcggca aataaaagtg cattatctga aaaagagatc
    16201 ttagataaat accagaatat atacggtgct gctgatgtca aaggacttca gatatcgaat
    16261 ctaaaagtag ataaaaaaga cgattctact tacagttttt catataaagc aaagatgaat
    16321 acctcattag gtgaattgaa agatctttct tataaaggaa cattagacag aaatgatggt
    16381 caaaccacga tcaactggca acccaacttg gtttttccag aaatggaagg aaatgacaaa
    16441 gtaagcctga ccacacaaga agcagcaaga gggaatatta tagatcgaaa tggtgaacca
    16501 ttagcaacaa caggcaaact aaaacaatta ggagtcgttc caagtaaact tggagatgga
    16561 ggcgaaaaaa cagccaatat caaagcgatt gcttcctcct tcgacttaac agaagatgct
    16621 atcaatcagg cgatttcaca aagctgggta caacccgatt actttgtccc attgaaaatc
    16681 attgatggag caacgccaga acttccagct ggagctacca ttcaagaagt agacggcaga
    16741 tattatcctt tgggtgaagc agctgctcag ctgattggtt acgtgggaga tatcacagca
    16801 gaagatattg ataagaatcc agaattaagc agtaatggaa aaatcggtcg ctcaggtttg
    16861 gagatggctt ttgataagga tcttcgtggg acaacaggtg ggaaattaag cattacagat
    16921 gcagacggtg tagagaaaaa agttctgatc gaacatgaag ttcaaaatgg caaagatatc
    16981 aaattgacaa tcgatgcgaa ggcacaaaaa acagcttttg acagtctagg aggaaaagct
    17041 ggatcaactg ttgcgacaac gccaaaaacc ggtgatcttc ttgcgcttgc tagctctcca
    17101 agctatgatc caaacaaaat gacaaacggg atctcacaag aagattacaa agcttatgaa
    17161 gaaaatcctg aacatccatt catcagccga tttgcgacag gttatgctcc tggatctacg
    17221 tttaaaatga ttacagcagc aatcggtctc gacaacggca ctatcgatcc aaatgaagtg
    17281 ttgacgatca acgggcttaa atggcaaaaa gacagttctt ggggatctta tcaagtaacg
    17341 cgtgtcagta gtgatgtatc acaagtagac ttaaaaactg ctttgatcta ttccgataat
    17401 atatatgcgg cacaagaaac gttgaaaatg ggtgagaaaa aatttcgtac aggcttagat
    17461 aaattcattt ttggtgaaga ccttgatttg ccaattagta tgaatccagc acaaatttct
    17521 aatgaagata gctttaactc agatatcttg ctagctgata ctggatatgg acagggcgaa
    17581 cttctaatta ctcctatcca gcaagcagca atgtattctg tttttaccaa caatggcaca
    17641 cttgtctatc ctaaattgat tgcagataaa gagacaaaag ataagaagaa tgtcatcagc
    17701 gaaacagcag tacaaacgat cgtgccagat ctgagagaag ttgtgcaaga tgtaaatggt
    17761 acagcacatt ctctttctgc tttagggatt ccgttggcag cgaaaactgg tacagcggaa
    17821 atcaaagaaa aacaggatgt aaaggggcaa gagaacagtt tcttgtttgc tttcaatctt
    17881 gataaccaag gttatatgat ggtcagcatg ttggaaaata aagaagatga tgattcagca
    17941 accaaacgag catcggaact attgcaatac ctcaaccaaa attatcaata aaaaattgct
    18001 ttttaagtac agtaaaagga ctgtggcgtt atcgtcacag tccttttttc aaataaacgg
    18061 ttttcacgat gtctctttca caacttcttt ttgatttact cacacttcat aaactttttt
    18121 tgtaaaatat ttgagaacaa gtggagaaat aagtgtactt aataaaatca cgataactaa
    18181 aggtgaatag tactgtggtt cgatcaattg actttgctgt ccaatttgta aaatgatcaa
    18241 agccatttct ccacgcgaaa tcataccagc accgaccatc aatgaactat gttgagaaaa
    18301 accggcaatc tgagcaccaa aataacctcc aagcaatttg gtcaaaatcg ctacaagcgt
    18361 caatatagaa ataaagagta gttgttcact aaagtcagaa aaatcaactt ctaatcctac
    18421 actgacaaaa aatactggta taaatactgc atatcctaaa gcctctacat tgtggtatac
    18481 ttcttcttta acctttgtct gactgacagc tatcccagca aaaaaagcac caatgacaga
    18541 gctaagccca acaagatccg ctacgtaaga cattcctaaa caaataacta gcgatacgat
    18601 gataatagaa gaatttgcgt acactttttc tgcaaatgaa agtaggaaag gcgcaatcca
    18661 tttgactaat aagaaaataa aaacaaaata aattagctgt tcaatcaaaa caagcggtaa
    18721 agaagcattg ctagaagctt cccccgttag aaaagatagg ctgaaactta gaactaaaac
    18781 gactaaaatg tcatctacca cagaagcacc caaaattgtt gatccttctt ttgtattcac
    18841 tacgtttagt tcttttaata cttctactga aatactgaca gaagttgccg caagaataat
    18901 cccaaagaaa atcgcttcat ttcccgaaac ttggaatgct ttgcctgtca accagccaaa
    18961 aacaaccggg aagatgatcc caagcaaagc aacgaacata ccaggtcgga aatatttttt
    19021 caaaagagat aaatcacttt ccagaccagc taaaaacatt aataagatca caccaatctc
    19081 cgaaaagtca tggactagaa tatcaggttt gacccaattc aatccagctt ggcctagcaa
    19141 aacaccaaca agtaattgtc caatcactgc tgggatacct aatctccgcg agatatgtga
    19201 gccaatcgtt gttgaaatca atatcaggca taaaatacca ataaattcca ttctcatcat
    19261 tcctttgtat aaaatatagc ccgaacttag cataacatac attattgaaa aaataggaaa
    19321 atatactcac aaaaaaacca acaatccaaa agattttttt ggattgttgg tttttatacg
    19381 gtctatttta ataactaaaa atgattaacg tatagtcatt tttcttattc tgatgaaatt
    19441 gataatctcc tggatgccca tgaaaatcaa aataaagccg aatatttgga atagaagcat
    19501 caaacttttg aatggattga acaataagac gaatccgcca atcaacaaca gaatactact
    19561 ataaacactc caacttttag cttttgtatt catgctgaag aacaactgga acaagctgtt
    19621 gatgataaca gctaatccaa gaagaatcgg caggatagaa acgattgcag gtgcaaaagc
    19681 atagacgatc agagctaaga tcaggaaaaa aagaccactg aacagaccga tactccaaga
    19741 acctgttttc cttttaaaac ggtaagcctc aaaaagattc aacaacccaa gcaaaacaag
    19801 ataggcggtg atcagataac cgataaaatg aaaaacagca gaagggttta gcacaatcgc
    19861 aatcccagaa ataatataaa cagcagctct taataaggcg tatttttgaa tattttgttt
    19921 aatcgtctca aacatataag aaaacctcct ttgacttatt ttaacgtgaa ctagtcattt
    19981 taccaaatta aatgttacaa aatgagcgaa ggagaagaat atctctggaa aaatcaactt
    20041 ctgaggatct tttccatttt tttgcctttt gctagctcat cgatcatttt atctaaataa
    20101 cgaatttctt tcatcaagtt atcctcgatg tcttctactc gtacaccaca aacaacacct
    20161 gtaatcaagg aacgtgaagg attggggaca ggggcttccg caaaaaattg ttcgaaagtc
    20221 acttgttttt gtagttgata ttctagttct gtttgggaat aacccgtcag ccaacaaatg
    20281 atttcatcta cttcctcttt tatacgatct tttctctccg cttttgctac atacatagga
    20341 taaacgcttg caaaacttgt cgtaaaaata cgattttgcg ccataatcag tcacctttct
    20401 ttttttcaaa ttatttacta cttatagtat ataagaaaaa gagaagaaaa agcgattatt
    20461 caaaaaaaca aaaaggattg tgacaaaatt cttgtcacca tccttttttc cgctctctga
    20521 ctttttacaa tcttcatagc tcaagtgcgc atcagataat cgaatgctcc taaagctgca
    20581 gtagctcctg aacccattga aacaatgatt tgtttgtatg gactatctgt acaatcacca
    20641 gctgcgaaaa cgccggggat attcgttgcg ccatttttct cggtcactat ttcatttctt
    20701 ggattcattt cgatcgttcc atctagccaa tccgtattag ggagtaagcc gactagaatg
    20761 aatactcctg aaacagctag tgtatgcatc tccatcgtac ggcgatcgat ataggagaga
    20821 gattctacct gattcgtacc gctgatttct ttcgtcgctg catgtttgat aacagtgaca
    20881 ttcgcaagag agactagttt atcctgtaag atttgatctg cttttaattc tggtaagaat
    20941 tctagaacat atacatgttt tgctaaccca gccaaatcga ttgctgcttc aacaccagaa
    21001 ttaccaccac cgataacagc aatctctttt cctttaaata aagggccgtc acagtgtggg
    21061 caataagcaa ttcctttatt tttaaactct ttttcgcctg gtacattgat agaacgccag
    21121 tgcgcacctg tcgcgatgat ggcggttttt gctttaagtg atataccgtt agctaagcca
    21181 atattaataa aatgttgctc tttatttaag gaaacggcct gttgattcat cataatgtcg
    21241 atagggtaac tacgcacatg actttctact tgctgcatca attttggacc ttctgtgtaa
    21301 gaggtaccaa tcatattttc aatccctagt gtttcaacga cttgtccgcc gaaagaatca
    21361 gcgacaagtc ctgtacggat tcctttacgt gctgcataga tagctgcact actagctgct
    21421 ggtccaccgc caatcactaa tacatcataa ggttcttttt caaacaactc ttcttcaatc
    21481 aaagggccag tgattttttc aacaatttgt tcgatcgtca tgcgtccgct actaaattct
    21541 tctccattta aaaacacagt tggcactgcc atgatttttt tatcatcgat ttctttttgg
    21601 aacatcccac cttcaatcat cgtatgagta atatttggat ttaatacagc taatatattc
    21661 aatgcctgta caacgtcggg gcaattatga caagtcaagc taacataact gtcaaaatgc
    21721 aatgtttgtg ttattttttt gattttaaga ctcaaagatt cactgatttt cggtgcccgt
    21781 ccactaattt gtaacatagc cagtaaaaaa gaggaaaatt catgaccgag ggggatacca
    21841 gcaaaaacga ttccactttc tttgccaact ggattgatag aaaaactagg tgtgcgcatc
    21901 gaatctcttt tttcccaaga gattttagga gacatttctg ctatttcctt cgtaaattca
    21961 gctagttttt gactattttc actattatcc aaactaacag aaaaaacaat aggagattca
    22021 atcagtgcta aatattgttc gagattttgt ttagtttctt tgtctaacat atccaccacc
    22081 taaatctttc caacaagatc aaaacttggt ttcaatgttt cgccactttc tttccatttt
    22141 gccggacaaa cttcacctgg gtgggtacgt acatattgag cagcgcgaat cttatcaatc
    22201 agtgcactag cgtcacgacc gattccatct gcattgattt ccatagcttg aacgattccg
    22261 tctggatcaa taataaatgt tcctcgctga gctaatcctt gctcttcatc caaaacatca
    22321 aaaatacgag aaatctgatg agacggatca ccgatcatca cgtattcgat tttaccgata
    22381 gcatctgatg tatcatgcca tgctttgtga gtaaagtggg tatcggtaga gcaagaaaag
    22441 acttcaacac ctaaagattt caatgtactg tattgttctt gtaagtcttc taattcagta
    22501 ggacaaacaa aagtaaaatc agctggatag aagcaaagaa tactccagtt ccccataaga
    22561 tctttttcac tgacttctaa aaattctcct tgatgataag catgtgcatt aaattcttcg
    22621 atttttttcc caatcaatga catagtaaaa cctccaataa taattattta tttataatta
    22681 ttgtaattta gttggagttg caaagtcaat ggatattttg ttatttaata aagattactc
    22741 aaaaacgaag gttaattata aaaatagaag aggtcgcaag aaaatgctac tgctggaaat
    22801 actcgggata acgttgagta acagtttcct gttctttcag catcatgtgt aagtgcaatc
    22861 ccgtttgaaa tcgagcttct tctggttttt tatcaactaa agccttgagt aaatcataat
    22921 gttgttccat gatcgtttcc catggaagcc cctgaatggt cactcgtaac cagcggaaac
    22981 gttctaaatg ggtattatgg tcatctaacc agttccaaac ttcttttctt cctgcaattt
    23041 cgaaacaagc ttcatgaaat aaattatctg cacggaaaaa agcgcgttcg tcatttattt
    23101 tgactgcttt ttcttgttct tctaaaatcg tttctagcac tattcgtgtt tgtgtgtcca
    23161 atttggaaca acattcaatc atgatttgct cttccaactg ttctcggaca aagcgagcat
    23221 tttctgcaga aacaagatta attttggaaa catacgtacc actttgaggt atcgtataca
    23281 cgagttcttg ctgacgtagt tgaatcaatg cttcgcgaat gggagtccgg ccgatagcaa
    23341 gatgttcctc cagtgccttt tcagatattt tccttccagg ttctaagtca gcatagataa
    23401 tttgtttacg aatcgcttga taagcttgtg attgcaagct gcttttcatc tttattcctc
    23461 caaaatcatt tctatgaacg tagtataaca gaagaggtct gaaaaacaat ctggtatgtc
    23521 acattaacta gtaaatttgt ataaatagta aaattttggt tgacatagcg atttttattg
    23581 cataaaattc acttgaatac aaaaactaat atgttagttt aggaggggaa aaatgattga
    23641 tttaaacaac tggaggaact ttatccctga attatctcaa aaagaagtag aaatacctca
    23701 ttttgaccgt gcatcattaa gagaaaatgg acaaaaaaat cctgtctgga tccatttcgg
    23761 tggcggaaat ctttatcgag gatttcatgc agaaatcgct caacgtttag cggatctagg
    23821 cgaattgtcc actggtgtca ttgtttgtga aacattcgat gaagaaataa ttgaaagggc
    23881 ttaccaagat tttgatgatt tgattcttga agtggtcatg ccaagcagtg gagagttcgt
    23941 caaacgtata ttagctgcga cagctgacag tctgtattgt catccagatt gttctgaaca
    24001 ctttgataag atgattcgac actttgaaaa tcctagttta caattagtta cttttgctat
    24061 tactgaaaaa ggttatcgat tgaaagatac aaataataaa tatataggac cgattgcagt
    24121 cgatataaaa aatggtccaa agaagccatc acatacaatg agtattcttg ctgtgctact
    24181 ttataaacgt tttttatctg gagcttggcc gattgcactt gtctctacag ataatttttc
    24241 acaaaacggt agtcaattac gtacttcttt gctaacgatc gcaaaagaat ggcaaaagga
    24301 aggttatgta caaaatacat ttatccaata cttatcgaat gaagaaattg ttgcgtttcc
    24361 atggacgatg attgatcgta tcaccccgaa tccttccttg tcagttagca aaatgttggc
    24421 aaaagagggc ttttcaaata tgtcgatttt ccaaaccgca aaaggaaata atattgctcc
    24481 atttgtcaat acagaggaca tccattattt aatcatggaa gatcattttc ccaatggacg
    24541 tccgaaattc gaaaaagctg gggtattctt gactgatcgt gcaacggtag ataaagcaga
    24601 tacgatgaag gtgacgactt gccttaatcc tttgcatacg tctttagcta ttatgggttg
    24661 tttactgggg tataggagca tagctgagga gatgaaagat ccagatttat cgctgctagt
    24721 ttctgaaatc gggtacaatg aaggcctccc agttgtggag tctccaggta tcattgatcc
    24781 aaagatcttt ctggaagaag taattactgt gcgcttttct aatccaaata ttcctaatat
    24841 gcctcagcga atcgccacgg atacctctca aaaggtggcg attcgttatg gtgagacgat
    24901 taaaaaatat atggaaatag aagttaaaga cccgcagaca cttgtattca taccattgac
    24961 tctcgctgct tggcttcgat accttattgg cattgatgat caaggaaaac cattcatccc
    25021 gagtccagac ccactattga cagaccttca gcataagctt tccgatattc aactgggtac
    25081 gcaagataca tcacatattc atgagaaaat ggctcctatt ttgtcaaata aagaaatttt
    25141 tggtgtagat ctttaccaag cagagcttgg cagaaaaata gaagaaatgt tcatcaagat
    25201 ggtagcagga ccaaatgccg tacgaaaaac attacaggat tacttacaag aacatggagg
    25261 aaatttatca tggaaatgac ttttagatgg tacggatcac aggaagaaaa gattacctta
    25321 gatgaaatca gacagattcc tgcggtcaaa gggattgtag gcacattgat ggatatacca
    25381 gtaggagagg tatggcctag ggagaggatc aaagaactaa aagaagaaat tgagtctcgt
    25441 gggttaacac taaaagtaat tgaaagcgtc aatgtgcatg atgccattaa aattggatta
    25501 ccttcccgtg agcagtatat cgaaaactat aagcagacaa tccgaaactt ggcagaatat
    25561 ggaatagaag tcatctgcta taattttatg cctgtatttg actgggtgaa atctgacctt
    25621 gactaccgct tagaagacgg ctcatccacg ttagctttta tatctgatga tattccagat
    25681 gatccaagag aaatcgtcgc gcgcatcgaa cattccagca atgaatttgg attgccggga
    25741 tgggaacctg agcgcttagc tcctatcaaa tccttgcttg aagcctatgc atcagtagac
    25801 gaagaaaaac ttcgagaaaa ttttgcctat tttctccaat caatcatccc aacatgtgaa
    25861 gaggtagggg tcaaaatggc tgtacatcca gatgatccgc catactcgat ttttggatta
    25921 gctcgaatcg taaagaatcg agaagattta gattggttgt gtcgcatagt agacagccct
    25981 tataacggaa tcactctttg tacagggagt attgcagaag atccagaaaa tgatgtatat
    26041 gggattttag cagaattttg ccaaagagat cgaatcccat ttgcacatgt tcgaaatatt
    26101 aaatttttag ctaatcgaga tttctatgag gcaccacata aatccgaata cggttcatta
    26161 gacatgtacc gcatactaaa aacaatgtat gacaacggat ttaacggata catccgtcct
    26221 gatcatggaa gaatgatctg gaatgagaca ggaagaccag gatacggctt atatgatcga
    26281 gcattaggtg ctgtttatct aaatggatta tgggaagcaa tcgaaaaagg aaacaaaagt
    26341 aaagataatt agtgaaaaaa actgtaattt tattatgtaa ataagaagga tgttcaaatt
    26401 cttgatacat aaatccggag gttgttaata agcattcgga tttatgtatc ttatttggtc
    26461 taggaagtaa cttgattttc ttttttcgat tgatccatga gtgcttcttc ttttaattca
    26521 aagatatatt ctgagatcct cataatcact tttttccagt cttctggtgt gatgattcct
    26581 tttaaaatat agattttttt gatatgagaa ggcaattgtt tcaaagggca gtcgctgata
    26641 acgatgttgc agttctccat aaaatcattt tgtattttga tcgattcatt tgaaaaaatt
    26701 tgttctatct taacgatcag atctttactg atataaaaat cacgcgtata gttcacacca
    26761 atcacaattc gcggctgttt tttgtagcga tcatacaaat gtactaggtc ttcaaccatc
    26821 cattgcacat tttccttttc taaaataact ggtaacaagt gttgattttg ttctctgaaa
    26881 tccatataaa attgttcaat ggcggtttgg acttctttca atacgctatg ttcttgataa
    26941 agcatgaaag taggaagggg cgtatttggt tgattgaagt taagaaatcc attataaagt
    27001 ttatttcgtg cgaatgccaa tgagtaaaga atcttttctt tttcaggtat aaacaaatca
    27061 aatacagtac aaagggactc caccatttct cttgaataaa gaacatgagg aacgtttgct
    27121 ttttttaaaa gtttgtattg ctccaagctt gtttcttccg attcgatttt cgtgatagaa
    27181 agtcgagcta aaatattcac taagatgcgt tgttcgcgac aaattggcag attaggtcgc
    27241 aaaatatcta cagagagatc aataaaaaag tcaatatatt catactctgt gaattctttt
    27301 tgtacgtctt tcacagaagt tgcaggaaaa ttctctttac atatttttaa tagaaaatat
    27361 aatttatcta tcataccgct atttagtcgg tcaagtactt cttttttaaa aaaagtattc
    27421 atcataaaag ccactacttg cggatcttca tcataaaatt ctgtagcagt acttgaaaag
    27481 atgttccaat aaatatctaa tgctgcatat tgaatttgta cctcttttcc agaaaaagac
    27541 tttctgccat tattagaaaa ggagatagac aaaccgtact atgctaaaaa tgcattaatc
    27601 tttttcattt tcgtatacaa ataagaggca ctatagtttg tttgctgact gaaactgata
    27661 atcgaatttg tctgacagct gaacaaagaa gtcaagatct gataactgac tgattcgttg
    27721 cagtatcttc caaatagacg ataatagcag taagccggat caattccttc aaaattcaac
    27781 tttaaaaaag gtttttgctt atcaatatgc agttctgtta gattgagacg ctcaaagtct
    27841 tgttctaatt ctttgatgta tagtaaaaaa tttgattcag acatatggaa atgatctgct
    27901 aaatattgtg tagtaataaa gaaacgatgt tcagatagga aaagaaaaat atctaatttt
    27961 gtattgcttt ttttcttcaa gataaacgtt ttaatcgctt cttgagtttg catgaaagag
    28021 gctccttttt acttaaattg ttaaaacttg aaaatattac tgtttttttc ataaatttag
    28081 acaaaaaaac agtaaacata taggtagaat ctctactatc ttatttcttg catacaaaaa
    28141 aatcaaggag tgagagagtt atgagatatt caaccatctt aatatcaaca tttgcagcct
    28201 taagcttatc gcttactata aatcagacag tccacacaga ggagacagaa acagccaaat
    28261 ggacagaaac caagtgggcc aacgtcaatc gaattacctt tcaggatgaa ttttcatcct
    28321 tcaattcagg agtcgcaaaa ttaagaaaag gacaaacagc gaccatcaaa gcaaaaattg
    28381 actattcggg agacttagca cctatactac aatcagctgt tacatttgag aatgttgatc
    28441 ccactttgtc gattggctat gacgagaaca ctttgactat ccaacacaag caagcgatat
    28501 ttaccttcac cgttacatta aatcaggact tgttaaaacc agcgcttttt actgtcaagg
    28561 tatcagatgg actaccgaac gatcatcatt taacgccgta tagtcagcgg cagacaattg
    28621 agcaagattc agccatcgac tcaggaggag atcttgttga agaaccaaca gataaaccag
    28681 aaaatgaaaa taagccagaa gtaccgccta cagaaaatcc agacggagaa cagaaaccgg
    28741 aaatagaacc tggagaagaa cccgatacag aaactcaacc agagccagac aataaatcaa
    28801 aacctgaaat aacccctgga gaaaaaccag atgtaactcc agaaccagat acggattctg
    28861 gaaaccaaac agtaccggaa acaaatccag acacagataa tgaaactgaa aatccagaaa
    28921 aaccagaggt agatccagaa gaaaaaccag atgtgactcc agaaccagat acggacgcaa
    28981 gagaccaagg aataccagaa aaaataaaca aaaaaacaat tcaagaggat ggaaaaaaag
    29041 agagtaaaaa atcaaatcta gcaattctaa aaataaatga agagcagctg aataaaaaat
    29101 cacgaatatt tgatagcgcc caatcagctg aaaccttaaa aagtagcaag gatacaacct
    29161 ttgctgtcct gaaacgaaaa ataaacagct accaaaatcc ggagagtcac aaaacaaagt
    29221 tatactgtgg agcggaatca ttctattaag tatagcaaca atgctttctg caaaaagatt
    29281 taaacaaaac agatctctct aacatttgaa taatgtctgt gaacgcattt ttcaaataaa
    29341 aagaaatatc cagaaaatga ccccaaaata ccagattgaa atctgatatt tggggtcgtt
    29401 catactttat ctttcttcat atttatttta agggatatct gtttcttttg gaagatggtt
    29461 cgggatcttt ttcactttca atacatctaa aaagaaggta aagatcggaa tgccgacaat
    29521 caagccccaa acgccaaaga accgttcgct aacaagtaag accacaaatg tataaaaaat
    29581 cggcagttct gttttgctgg acatcaactt cggattcagc acataagact caattagatg
    29641 gacaatcaaa atcgtaatca ggatataaac aacatctcgg atgcctcctt gggaataagc
    29701 tatgaaagat agaggaatac aagaaatgat aacacctgct actgggatca gacttaaaat
    29761 gaaaatcatg atcgctaaac tcagcagctg atgaaagcca aatacagcca aggcgattgt
    29821 agtgagcaac gtatttaaaa gagcgacaac aaattgagct tctaatacca aaccaaatgt
    29881 attgacaaac ttatcggcaa aatagtaaat atcttgaaag aaccaagaaa attcactttt
    29941 taaaaacaat cttgagaata caattgtttt tttcttttca atcataaaaa agaaacttaa
    30001 gatgaatgac atagcaaacg ccactgccat ttttcctata tcctgtaaat agccaagcgc
    30061 aatcgaagcg ccattttgaa gctgttcaaa aaaatcgttt cgctcaatat aagtatggat
    30121 atattgtaaa acaggatctg catcttttgg ctgatgctcg taaaaattaa taacggactg
    30181 gatcatgtca aatgtttgat gaataagcat cgggatatac tttgtgaatg ccagatagat
    30241 aaggtaaacg atcagtgtat aaatcatgat agctaaaaca cctgtaggga ttcggacaaa
    30301 tcgctgaatg atttgaacaa gatgaatcat caaataagta aagataaatg tgagcaaaat
    30361 ggttgtaatc atacttctaa ctaagaaaag aacaaaaacg acaaataata aaacagtgag
    30421 acggcgtatt ttttcattcg ccaaaaaacg ctgataaacg gtcaaatcga caacctccaa
    30481 ataacaaaaa ataaacacgt tattcattat atgatggaat atgaaaataa gaaagagcaa
    30541 aaagaaaaac cgctaaatga cgttatctta tgagttggtt ttcctcataa aatcgttcat
    30601 ctagcagttt cagccctttt tctggtcttg atgaaaatta tctagcattt ttcgggtcag
    30661 atgttgcagt gtatccaatt cttcctgttc aagtggaaga taagacttga tcttttgtgg
    30721 aataccttct gcttgttttt gcaacgcagc accttgagca gtcagcgtaa catttacgat
    30781 tctttcatca cccgtttcac gctgacgatt aatataattt ttttctgcta acttttttag
    30841 taagggagtc agcgtaccag aatccagaca caaatcattt cctagctctt tcactgaagt
    30901 ctttttcttt tcccataaaa ctaacatcac aagatactgg gtataggtaa gattcagcgg
    30961 cttgaggagg ggagtgtagt gtctaatgat ttctttagag gcggcatata aaggaaaaca
    31021 tacttgatta actaaatata gatcttccat ttttccacct ccgctgtttt actatagtgt
    31081 atcatagcgg atttacacaa aaaagtctat tcactaactg ctttcagagt aacttctata
    31141 tttccagctg tagcttttga atacggacac actttatgcg ctgcctctaa taattcttgc
    31201 gtttcttcca gagaaagacc ttcgatagat ccttcaatct ctacacctaa gacaaagctc
    31261 gtttcacttt ctgaataaag ggaaacttgt gcactgacag tagaagcccc agagatattt
    31321 ttttgctgtt tgatcaattc taatgcactg ttaaaacatg cactgaaacc agctgcaaac
    31381 aattgttcag ggttggttgc attttcgacg cgtttaccat gagctgcaat attcaattcg
    31441 aatgtacgat cgggattatg cacttctcca gagcgtccgc ctgtgttgat cattttcgta
    31501 gaatacattt ttttcataaa attaccacct ttaattatat tttatacaat tgaattttac
    31561 acaatataat tgtggaaagc aaagaaatgg attggcataa gataaataag agaaagcaca
    31621 tgaaacagac gcgctttctc gaatagcaaa catatacaaa aaatatcaga gacaaaaaat
    31681 aatctcatca taaacattac atatatttct caaaaagttg ttttctttct tcaaaaatta
    31741 cttcacgatg gacctgatga agcatccata aataaccaaa aggatctctg aacattgagt
    31801 tagtcacacc aaagtccatc atttctgtca tttcttgaat ctctacacag ccatttcgta
    31861 atgctttatt atgtgtgtcc tcgatatcag agacgatgat attgaaccag atcgtatttg
    31921 gatgttcagc agtaggagca gtcaaaccaa gagacgtgtt ttcatccagc atatggaatc
    31981 tcgtaccata caaggtaaaa atgacttcat tattgcctct agggtaatct gttgcctcaa
    32041 tcagttgtat ttcatcaaag attgtttgat acagttctag tgctttcaaa ctatcattta
    32101 atacaaaatc gatttccgtt cctttatgca taaagatctc ctctcctttt cagtcgaaca
    32161 gttactagat tcttttatta taccagctaa agaaaacgca ttcaaaaaaa tagcggattt
    32221 acttaccaac tcattcgatt ggatgataag taaatccgcg tcccattact tctgctacgc
    32281 tgctgacaat gacaaaggca cttggatcga tttcttctat caatggtttc attcgggaaa
    32341 attcatgatc agtcacaacg atcaataaaa cctcttttga ctttcgatta tacccgcctt
    32401 ttgcctctag cagggtaagg ccacgtccaa tctcagcact taagcgaagg cggatgtctt
    32461 ccaaataatg ttcactcatg accataacag atttctttcg attgatacct gtttcgatat
    32521 aagtcatgac aattgaagtg attgcaatag ataaaatagc ataaagaaac tcttctattc
    32581 caaaaataaa cagattaaga gaaacaacga atgcgtctgt aaaaaataag ccaatcgaag
    32641 tattcaagtg gaaatatttt ttaaaaatga ggggagggat cgtcgtaccg ccgctagaag
    32701 agttgttttt atataaaatc gcaactccta aagcaaaaat cgcacttcca aaaatgacag
    32761 acaacaaccg atctgaagta atcattgttt ctggaactat tgcaatgatt aaaggaaaaa
    32821 ccaagcttcc gaaaagtact ttaaaaaagg gttttttacc taaaaataga agagctagta
    32881 ccaacataac gatattcaac actaaaataa ctatagctcg gtcaaagcct aaagcagctt
    32941 ccagtaatat tcctagaccg ctgacacctc cagcagcaat atgatgaggc cctaaaaaca
    33001 tattgatagc gactcctaat atgaagaggg caaaaataat cttaatgtat gtccatataa
    33061 attgtctcgt ttctttcatt tattcacttc cttaattcat taataatact cttatcttat
    33121 tataacttac ttttcacctt aagttaactt taattaataa aaaaattagg ctagtctaaa
    33181 ttattatgtt tcattcttct agaatatact tctacgccaa aaactgttaa aaaactttta
    33241 ctttagaaaa ttggagaaat tgatcgctta agataaattc aggacactaa atagtacagg
    33301 aagtagacta aaacttttaa aagttttaag tctatctatt tggcaagttt aaaaaataaa
    33361 aattcggtat caaaaaactg ttaccgataa catttttgaa agcgttgtct tttgcttctc
    33421 tatcacttat agtgatgacg tcatattaaa acacaaggag gaaatcaatg gatacagctg
    33481 caatttatca tcgaccggaa agtgaatatg catttctata tacgaataca agatttcgta
    33541 ttcggcttcg tactaggaaa aatgatatca aaaaagtata tgtgctatgt ggagatccat
    33601 ataccataac aactgaaaaa tggtatcaaa aacaacgacc aatgaaaaaa tgtctaagta
    33661 ccaatgttca tgattattgg gaaattgaag tgacgagcga aacaagtcgc ttacagtatg
    33721 cgttccatgt tgttggggaa gataacacgg actgttttta cggtgatcaa ggaatttttc
    33781 cttatcgaga aaatgtgatt actgaaccaa atttttattt tcgaatacct tattttcatc
    33841 aaatcgatcg attcactatt ccagaatggg taaaagaaac agtatggtat caaatttttc
    33901 ccgaaagatt tgcaaacggg gacaaagcaa atgaccccga acacacttta ccttggggaa
    33961 gtaaagatcc agaccgagaa gactttttcg ggggagattt gcaaggtgtg atggatcatt
    34021 tggattactt gacggacctt ggcatcaatg gcatctattt ttgtcccata tttaaagcca
    34081 catccaatca taaatacgat acgattgatt attatgaggt ggatcccgct tttggcgata
    34141 aaaaactttt aaaaaacttg attgatgaag cacataaaag agggatacgt atcatgttcg
    34201 atgctgtatt caatcatatg ggtgtccatt caccacagtg gcaagacgtt ctcaaaaacg
    34261 gagaaaaatc gatctataaa gactggttcc acatccgttt tttcccagta gattcttatc
    34321 agatgactga cttaccagaa actgctgaaa atatcccata tgatactttt gcttttactc
    34381 cattcatgcc gaaactaaat acagcaaatc cagaagtgca aaaatatttg ctggatatcg
    34441 caacttattg gataaaagaa ttcgatattg atggatggcg tcttgatgtt gctaatgaag
    34501 tcgatcatca tttttggaaa aaattcagag aagcagttac agaaatcaaa ccagacatct
    34561 atatccttgg agagatttgg cattcctctc aagcttggct gcaaggggat gaattccatg
    34621 cagtgatgaa ttatgcattt acagattcga ttaaagatta ttttgcaaaa aagaaaatca
    34681 cagcttcaca aatggtcagt ggaatgaatc atcagcaaat gctttacaga gatcaggtga
    34741 acgaaggaac attcaactta ttagattctc atgatactgc caggatcttg accctttgcc
    34801 aaggtaacaa agaattgatg aagtctgtga tggcctttat gtttcttcaa aaagggtctc
    34861 cttgtatcta ttacgggaca gaaataggga tgactggtga agatgacccg gattgccgca
    34921 aatgtatgat atgggagaag gaggaacaag atctagagct attcggtttt ataaaagaac
    34981 ttgtttctct aaggaaacag ttgtctaaga ttatttctga aggttctact cagtggctaa
    35041 tagtaaatga tcgtgaagat aagctctatt tcacacggaa actagaggga cagatcatct
    35101 atgtttactt taatcagtca aaagaacctt gggtagtaga acaggaaaat gaggtgattc
    35161 ttagtcaaaa ttgtcagttg ttagaagacg ggaaagcaga gatacgacaa tacggatttt
    35221 tgatcatgtg ttgaaaactg ttaccggtaa caacaagaaa gcgtttgcaa atgaagattt
    35281 gtgcccatta taataagggt gtaacagcac gttgaataca aaggaggaaa tgaagatgaa
    35341 aaaaagaagt gtgaaacagt tgggtttagg gttaatctct ttaggaatct taggcggatt
    35401 agcggcttgt ggcaatggta actcttcagc agaaggggaa gccgatgaag gaaaaacgtt
    35461 aacagtttcc gttgattctg gatataaaga ttatataaac gaaataaaaa acactttcga
    35521 aaaagaaaac gatgtgaaaa tcaagctagt agaaaaggac atgttcgatc agttggaatc
    35581 attagcgtta gatgggcctg ctggaaaggg acctgacgtt atgatggcag catatgaccg
    35641 gatcggtgcg ttaggacagc aaggacatct ggcggaagta aaactgggaa atgaagcagc
    35701 ttacgatgaa acagacaaag cccaagtgac ttatgatgga aaaatctacg gagaacctgc
    35761 agtaatcgag acccttgttt tgtactataa caaagattta gtcgatacag caccatcaac
    35821 gtttaaagat ttggagaatc tatccaaaga cagtcgtttt gcttttgagt cagaagcagg
    35881 aaaaaataca ggatttttag ctaaatggac tgacttttat tattcctatg gtttaattgc
    35941 aggttacggt ggctatgtat ttggtgatga tggcacaaat ccttcagata tcggtttgaa
    36001 taatgcaggt gctgtagaag gaatctctta tgcaacagat tggttcaaaa atgtttggcc
    36061 aaagggaatg caagacataa aaagtgcagg agacttcgcc agccagcaat tcatgtccaa
    36121 taaaactgca gcaatcattg acggtccatg gcaagcgcaa acatacaaag aaaacaatat
    36181 caattatggt gtagccaaaa ttcctactct aaataatgga cagccttatc aaccgtttgg
    36241 cggaggaaaa ggatgggtag tcagcaatta tgctaaaaac aaagacctct ctcaaaaatg
    36301 gcttgattat gtaacgaatc aggaaaatca agaaaaattc tttgaaatgg taaatgaaat
    36361 ccctgcaaac caacaagcta gggaaacagc aaaggctaaa aacgatgaat taacaacagc
    36421 tgtgattgaa caatatgaaa cagctcaagc gatgccaaac atcccagaaa tgggcgaagt
    36481 ttggacaggt gcagaaaact tgatgttcga tgcagcatca ggttcaaaaa caccaaaaga
    36541 atccgcagat gaagcagtaa aaacaatcag tgaagccata gaacaaaaat actgattaaa
    36601 atgataaccg tccattttta taaaaaatgg aacaggtgct tcagataaaa gtggcaagag
    36661 cgagatggaa aattatcttg ctcttgttgc cattatctta aaagcagttt gcggtttagc
    36721 aagtttagag ggggcattca gatgcagcaa gataaaacaa gcaatatcaa cgaaaaaaaa
    36781 atcacgcttt gttcacttat tccagggatg gggcagtttg taaatggcca agcttttaaa
    36841 ggtatcgttt ttttcgccat attcgtccta ttcattggtc agatgcttct gggcggattt
    36901 catgcattgg taggattggt tactttggga agtataccaa tggaagatca ttcattattt
    36961 attttgattg aaggcacttt gcaattcatc attacaatca ttttcttgat tttttacggt
    37021 ttgaatcttt tagacgctta tcgagtagcg aagatgcgtc aagagggcaa aaaaatcaat
    37081 cggacgatga aggaagtcat acataatata ggtgatgaag gttttcctta tctattgaca
    37141 cttcccgctt atcttctcat gatttttacg atcattttcc cagtcctagt tacattgttc
    37201 actgcattta ctaattatga cttcaatcat attccaccag ccagtttaat tgattgggta
    37261 ggggctaaaa acttttttag tatcttcttt ttaagctcat atcgtaatac tttttttgca
    37321 gtcttttcgt ggaccgtgat ttggacttta tgtgcaacaa ctttgcaaat cacccttggt
    37381 attctcacag cggttgttgc tcaccagaaa tttattaaat tcaaacgtat tttcggtatc
    37441 attttcttat taccatgggc ggtcccagct tttattacta tcatgagttt ttcgaatata
    37501 ttcaacgata gcgtaggtgc catcaatact caagtgattc ctttcataaa ccagcttcct
    37561 tttgtagata tcagtgcaat ctcttggaaa acggacccga actggacgaa agtagcaatt
    37621 atcttagtgc agggctggtt aggatttccc tatatctatg tgatggttac aggaatctta
    37681 caatcgattt cagaagactt atatgaagca gcaaaaatcg acggagcaaa tgcatggcag
    37741 cgcttttcaa acatcacgct tcctgctgtc ttcctagtgg cagcgccaac atttattaca
    37801 cagtatacgg ggaatttcaa taatttctcc atgatctatc tgtttaacaa tggcggtccc
    37861 ggaagcgtag gcggaggagc tggttctact gatattctta tttcctggat ctataaactt
    37921 acgactggaa cttctcagca gtattctatg gcttcagcaa tcacgttgat tatctccgtc
    37981 atcgttatct gtgtgtcatt gctggtattt aaaaagacaa atgcgttcaa tatgggggat
    38041 taacaatgaa aaaatttcat tcgagtgctc gattccaaaa acgactttct cactttttta
    38101 cttacttttt tcttttaata ctgtcagtca ttatcatcta tccgcttttg atcacagcaa
    38161 gtactgcctt caagtcagga aatattgcag cttttagttt agatctttca agtgactgga
    38221 ctttaggaaa ctttactcgg ctattcagtg aaacacttta cgggacttgg tataaaaata
    38281 cattgatcat ttctgtccta acaatgatcg tacaagtgac tgtagtaact ttggcgggct
    38341 atacttatag tcgctatcgt tttatcggcc gcaaatcaag tttgatgttc tttttagtga
    38401 ttcagatggt accgactatg gcagcattga ctgcctttta tgtcatggct ttcttattag
    38461 aagcgctcga taagtactgg ttcttgacaa tgatctatat aggcggtgga attccaatga
    38521 atacttggct gatgaaagga tactttgaca ctgtaccaat agatttagat gaatctgcta
    38581 aacttgatgg ggcagggcat ttcaggattt ttttccagat tgtattaccg cttgtcaaac
    38641 cgatgctcgc cgttcaagca ttatgggctt ttatgggacc ttttggggat ttcatgttag
    38701 ctaagttcct gcttcgaaca cctgaaaatc agactgttgc tgtcggctta caaacattta
    38761 tttctgatgt gacaaaccaa agagtctctc tttttgctgc tggggcaatt ttgattgcac
    38821 taccgatttg tctattattc ttctttttac aaaagaactt tgttaccggc ctgacatctg
    38881 gcggaacaaa aggataggag cagagtatca tgcaaacatt tccgttaaac tatttttccg
    38941 cattacgtac gccaactcaa gtgtttgcgg gacgcaaact attatcatgg cctaaatttt
    39001 tcttgatatt tgtattttta gtttccttga tggtcatgcc tgtgactctt ttttatgcca
    39061 atcagatcca agcgattcca ttagaacaat ttctatccgt tcattcgctg atcgatgaac
    39121 aaggaaccca aaaattttct gaacttgaat tatctgaaac tgggttacaa gcatcgcaac
    39181 aaacgatagc tgtgacccct gaaattttgg taggtgtgtc tttatctgag aaacaacaat
    39241 ccgatcatgg aacttttatt gattttgaga aggaacaatg ggtgatccaa caaaaggata
    39301 aatctggtat acgccgctat acgatgaatt atagcccatc tttccaacca gattctgtac
    39361 gtacgcccga agatttccaa cgatttttag aaagagaatt ttatgccagt aatcgtccaa
    39421 caatcatttt atcttatagt ttaagtcttg gtcttgtcct atttgtcatg acgagtctca
    39481 ttttattcgg ggcttccttt ttcttgtgga tgacaagaaa aagccaactt tcatccattc
    39541 atacattcaa agagagtgca aatttgatgc tgaatgttat gggaataggt tccatggcag
    39601 cagcagttgt agggtttatc cactttgact ttatcttgat gctaagtgtc caaacaacga
    39661 taactgtctt gctgctttta tgggtttttg tcaaaacaag attcaaagat aagcgtgtcg
    39721 aatgacaagt ttaagcgatt tatgcgacaa tgaatgtgaa aaaaatgaaa aataaagtag
    39781 tttttgaaaa atttctgaaa aaattaaact tcttagttga ttcttttctt ttttagtatt
    39841 aacgtaatag ggtagttttt ttaaggagga aaatcatgtt agagaaaact ttatacaatc
    39901 aattattttc acgttctttc tcgctccctg tcgaagtaaa ttattgggac ggtacaacga
    39961 aacaatacgg agatacggac actcctcccc aaatcaaaat caatatccat gaagaaatcc
    40021 caatgaaaga gattacaagt aacgcatctt tggcactagg agaagcctat atggatcatc
    40081 gaatcgagat cgagggaagt atccaagcat tgatcaacga tgcttatcag caagcaaaca
    40141 gctttttacg aggaaaagat tatctaaaat ggctgccaaa gaaagaaaaa catacgaaac
    40201 aaaaaaacaa agaagatatc catgcgcatt atgacttagg taacgacttt tataaacttt
    40261 ggctagatcc aactttgact tattcttgtg cttatttcaa tacacctgaa gatacgttgg
    40321 aacaagcaca aatcaataaa gtccatcata tcttagacaa actctttatc aaagaaggcg
    40381 aaacgttgct tgatatcggt tgtggctggg gaacattgat gttcactgct accaaagagt
    40441 ataatgtcaa ggcaactggg atcacactaa gtgaagaaca atacgatttg attaccaaaa
    40501 gaataaaaga agaacattta gaagataaat gccgtgtatt attaatggat taccgcgaac
    40561 taaaaggcga aacgtttgat catatcacaa gtgtaggtat gttcgaacat gtaggttctg
    40621 aaaatcttga aggttatttc aaagtggtaa aagatttatt gaaaccaaaa ggaacagctt
    40681 tgatccatgg aatcagccga caacaaggcg gtgcgacaaa tgcttggatc aataaatata
    40741 ttttccctgg cggttatgtc cctggtgtta ctgaattagt tgataatatt acaaaaaacg
    40801 atttgcaact gattgatttg gaaagcttac gtcgtgacta ccaattgaca ttagaacatt
    40861 ggacaaagaa ttttcatcaa gtccaagatc aagtcacgaa agaaatgggt gattccttct
    40921 atcgaatgtg ggatctatat ttacaagctt gtgcagcttc atttgaatca agtaatatcg
    40981 atgtgattca atatttgctt gttcaacctg gaaacaatga catcccaatg catcgtgcat
    41041 aattgaggca aaagtactgt ttaaagacta tttaaaaaga agctaagttt tatgatgctc
    41101 cagaagtgaa cttttttgtc taacttctag gattgtctct aaagcttagt tt
//
LOCUS       DAFBVQ010000018        40372 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.018, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000018 DAFBVQ010000000
VERSION     DAFBVQ010000018.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 40372)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 40372)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..40372
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.018"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(163..2160)
                     /gene="tkt"
                     /locus_tag="LLC22_001140"
     CDS             complement(163..2160)
                     /gene="tkt"
                     /locus_tag="LLC22_001140"
                     /EC_number="2.2.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transketolase"
                     /protein_id="HBK5434430.1"
                     /translation="MFDKIDQLGVNTIRTLSIEAVQKANSGHPGLPMGAAPMAYALWT
                     KHLKVNPTTSKNWADRDRFVLSAGHGSAMLYSLLHLAGYQVTIDDLKQFRQWDSKTPG
                     HPEVHHTDGVEATTGPLGQGIAMAVGMAMAEAHLAATYNKENFNVMDHYTYAICGDGD
                     LMEGVSQEASSMAGHMKLGKLIVLYDSNDISLDGPTSKAFTENVGARYEAYGWQHILV
                     KDGNDLEAISKAIEEAKAETDKPTLIEVKTVIGYGAPKEGTSAVHGAPLGEDGIKMAK
                     EVYGWEYPDFTVPEEVAARFHQTMIEEGQKAEDAWNEMFANYKKAYPELAQQFEDAFD
                     GKLPENWDAELPTYEVGSSQASRVSSKEVIQELSKAIPSFWGGSADLSGSNNTMVAAD
                     KDFTPEHYEGRNIWFGVREFAMASAMNGIQLHGGTRIYGGTFFVFVDYLRPAVRLAAI
                     QHTPVVYVLTHDSVAVGEDGPTHEPIEQLASVRCMPGVQVIRPADGNETRAAWKVAME
                     TTDAPTILVLSRQNLPVLPSTKEVADEMVKKGAYVLSPSQGETPEGILIATGSEVDLA
                     VKAQKELAEKGKDVSVVSMPSFDLFEKQSSEYKESVLPKSVKKRVAIEAAASFGWERY
                     VGTEGATITIDHFGASAPGTKILEEFGFTVENVVNTYNQLS"
     gene            complement(2262..2513)
                     /locus_tag="LLC22_001141"
     CDS             complement(2262..2513)
                     /locus_tag="LLC22_001141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF896 family protein"
                     /protein_id="HBK5434431.1"
                     /translation="MLSPEKIERINELARKKKENGLSKAEEQEQINLRKEYLEAFRSG
                     MRHHIEGMKVVDPEGNDVTPEKLKEIQKKKGLHNRNDNF"
     gene            2660..3283
                     /gene="lexA"
                     /locus_tag="LLC22_001142"
     CDS             2660..3283
                     /gene="lexA"
                     /locus_tag="LLC22_001142"
                     /EC_number="3.4.21.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751062.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor LexA"
                     /protein_id="HBK5434432.1"
                     /translation="MARQTESRQIEVLRYIHEQVTQKGYPPTVREIGEAVQLSSTSTV
                     HGHLARLEKKGFIQRDPTKPRAIELTKQGLEKIGIRPTTIPVLGVVTAGEPILAVEDA
                     SDFFPIPPNLSSEEGSLFMLTIRGDSMINAGILDGDNVIVRKQETAQNGDIVIAMTAE
                     DEATCKRFYKEKNFFRLQPENDLLEPIILDQVSILGRVVGLYRSHIY"
     gene            3463..3681
                     /locus_tag="LLC22_001143"
     CDS             3463..3681
                     /locus_tag="LLC22_001143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434433.1"
                     /translation="MKSMRRLGLVLTVLFLGIIIGNFGIRPALLVFVPLFTLWFMLWD
                     EKKYRQSERRRIHEDHFYHEPYYRSRQS"
     gene            complement(3970..4482)
                     /locus_tag="LLC22_001144"
     CDS             complement(3970..4482)
                     /locus_tag="LLC22_001144"
                     /EC_number="2.4.2.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenine phosphoribosyltransferase"
                     /protein_id="HBK5434434.1"
                     /translation="MDLKDYIASIPDYPSKGIVFRDISPLMADGDAYREATKQIVNYA
                     KEKRIDMVVGPEARGFIVGCPVAYELGVGFAPVRKKGKLPRETIEVTYGLEYGTDTLT
                     LHKDAIKPGQRVLICDDLLATGGTIKATIELIEQLGGVVVGCAFLIELMDLHGRDKIK
                     GYDIITLMEY"
     gene            complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="LLC22_001145"
     CDS             complement(4496..6793)
                     /gene="recJ"
                     /locus_tag="LLC22_001145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded-DNA-specific exonuclease RecJ"
                     /protein_id="HBK5434435.1"
                     /translation="MRQANFDWKLSETEPSESFLQMIRELKLSPFVGKLLWQRGYHEE
                     KDINRFLHPKEQELHDPYLIHDMDKAISRIQEAVISGEKILVYGDYDADGITSATVMK
                     ETLELLGAEVEVFLPNRFEHGYGPNQSVYQEKIEEGIQLIITVDNGVAGNDAVAYAQQ
                     AGVDVIITDHHELPENLPDAYAIVHPRHPAGHYPFPDLAGVGVAFKVASALLEEPPAE
                     FLDLVAIGTIADLVSLTDENRILVSLGIDAIHHSERIGLQALFEESGVKMRDADETTI
                     GFSIAPRLNAIGRMGDPRPAVSLLATFDEEEASVQAKKLNEINEERKAIVEQITQEAL
                     AMVNKENHIHLLVNRGWHEGVLGIVAGKIMNETGKPTLVLTLKEDGSAKGSGRSIEAL
                     NLFEMLDQMRDLFTYFGGHHAAVGLTMPSENVTILQEKMNQYIVDHQIDLMRGPELRI
                     DEVLLPNEVTVERIDELKLLAPFGTDNPLPQFLFRQVQAENIKRIGANQQHLKFVLSD
                     ASSQLDAVAFGFGTQEEELLNNQVDVVGKLSINEWNGRKKPQLMVSDFSVGGLQVFDW
                     RAKRFREQSRTSEGSLYLAFDSSTLKFVPEIIQEAAIVFEGLDSVKAIIEKRKPNSLV
                     VMDCPDDLADLKEVFRSYSFNRVYLMGISPDEAYLNGVGTREQYAKLFKLIHSQERID
                     IRHKIKAIAQYLRIPEKLLIFMIQVFFELKFVTIENGVLQKVASPESHPLTESRLYQR
                     RLNKIKVEEFLLLSDIPTIKKWLTT"
     gene            complement(6935..7378)
                     /locus_tag="LLC22_001146"
     CDS             complement(6935..7378)
                     /locus_tag="LLC22_001146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303793.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1049 domain-containing protein"
                     /protein_id="HBK5434436.1"
                     /translation="MKELKKQSNVILGFVLVLIIVLFAVLNNKNVPVSFGFTSFSAPL
                     ILVIIGSALIGALIVFLTASATLWQQKKQIKQLTQEMSEYQTELQKKIEEAKEEQQRE
                     FRNERAELEAAYQAELQAKTAQISQLKAPEEQKTQSPKQSFNYFD"
     gene            complement(7379..8167)
                     /locus_tag="LLC22_001147"
     CDS             complement(7379..8167)
                     /locus_tag="LLC22_001147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5434437.1"
                     /translation="MNLEDKVVLVTGSSGGLGAQICYEAAKQGAIVISCARRMAFVEG
                     VRDECRRLSGKEAYAFKVDVSNPESVDELYEKVMEEVGRVDILVNNAGFGIFEDFLTF
                     DLGKAYDMFEVNILGMMVLTQKFAIDMAERRQGHIINIASMAGKMATAKSTVYSATKF
                     AVLGFSNALRLELKPLGVAVTTVNPGPIETNFFDKADPSGSYLEKVGQIVLEPAKLAK
                     MIVRNMRHPKREINQPFILEVASKFYTLFPTIGDYLASGIFNKK"
     gene            complement(8164..9105)
                     /locus_tag="LLC22_001148"
     CDS             complement(8164..9105)
                     /locus_tag="LLC22_001148"
                     /EC_number="3.1.26.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Z"
                     /protein_id="HBK5434438.1"
                     /translation="MELQFLGTGAGVPAKHRNVTSIALKLLDERNEVWLFDCGEGTQM
                     QILRTTIRPRKIGKIFITHLHGDHIFGLPGLISSRSFQGGDTPLEIYGPKGIEEYIKV
                     SLGISQTRLSYPLKFIELNETAPIFTDQQFSVYTKKLNHGIDSFGYRVVEHDHKGELQ
                     VDRLKELGIPAGPLYGKLKQGETIQLEDGRTINGKDFVGPDKKGRIVTILGDTRKTHN
                     SVVLAENSDILVHESTFNKDEARMAHNYFHSTTHQAAEVAKEAQAKRLLLTHISARYL
                     GKAALELEKEAQEVFENTTIMKDFDSIEIPFREEEEA"
     gene            complement(9282..9869)
                     /locus_tag="LLC22_001149"
     CDS             complement(9282..9869)
                     /locus_tag="LLC22_001149"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1269 domain-containing protein"
                     /protein_id="HBK5434439.1"
                     /translation="MSKRVIILNFQVESQAYQAFSEIKKLHAVRSIKGEQMAVVSHDP
                     NGTHQFKIEDFIDFTGNNKSSTGGLIGMLVGVLGGPLGILLGWFAGGMIGATQDAKEI
                     KDAQTVFDFVGNKIGEGATGLILIADEEDNRPLNQLVMMELGGEITRLDYEDVEKDVH
                     DAKEAENHAKEAAQKTWKDKHPQTSNDNESSGSSN"
     gene            complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="LLC22_001150"
     CDS             complement(10090..11397)
                     /gene="obgE"
                     /locus_tag="LLC22_001150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase ObgE"
                     /protein_id="HBK5434440.1"
                     /translation="MFLDQVTIDVKAGKGGDGMVAFRREKYVPDGGPAGGDGGRGGDV
                     ILIVDEGLRTLMDFRFNRHFKAQPGENGMSKGMHGRGSEDTYVKVPQGTTVRDAETGA
                     LLGDLIENGQTLVVAKGGRGGRGNIRFASPRNPAPEIAENGEPGQERKIELELKVLAD
                     VGLVGFPSVGKSTLLSVISSARPKIGAYHFTTLVPNLGMVTTSDGRSFAAADLPGLIE
                     GASQGVGLGTQFLRHIERTRVILHVIDMSGMEGRDPYEDYLAINKELSTYNLRLLERP
                     QIIVANKMDMPDAPENLVKFKEQLNKEKEDEFADDIPVFPISGVTRQGLDALLNATAD
                     LLEVTPEFPLYEEELEEETVHYGFNPEGPEFQIDRDSDATWILSGEKIEKLFQMTNFD
                     HDETVMRFARQLRGMGVDEALRARGAKDGDLVRIGEFEFEFVE"
     gene            11691..12701
                     /gene="gap"
                     /locus_tag="LLC22_001151"
     CDS             11691..12701
                     /gene="gap"
                     /locus_tag="LLC22_001151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBK5434441.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIKEVSDDIEVVAINDLTSPTMLAQ
                     LLQFDSTHGTYPGTVTATEDSIVVDGEATRVYAEPDASKIPWAKENGVDIVLECTGFY
                     TSEEKAKAHLDAGVKRVVISAPAGAMKTIVYNVNDDTLDENDKIISAGSCTTNCLAPM
                     AYFLNNEFGIEVGTMTTVHAYTSTQMLLDGPVKGGNLRAARSAADNTIPHSTGAAKAI
                     GLVIPELQGKLQGHAQRVPVVDGSLTELVSVLKTKVTADQVNEAIKKHTVDNPSFGYD
                     DRQIVSSDVIGTTQGSIFDPTQTEVTTAGDFQLVKTVAWYDNEYGFTCQMIRLLEKFA
                     NL"
     gene            complement(12786..13721)
                     /locus_tag="LLC22_001152"
     CDS             complement(12786..13721)
                     /locus_tag="LLC22_001152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5434442.1"
                     /translation="MKLWMKILLGVALALIVALVFAGNYFYNYAVVPSEKDFLDEDTP
                     GTTQTSKETDAHKWFSSKENRSDWTITSKDGLKLSAIYLPAETKSEKTALVAHGYMGN
                     AETMTNYAKMFHDMGYNVLVPDARGHGKSEGDYIGFGWPERKDYVQWINKVLENNGKS
                     QEIVLYGVSMGAATVMMTSGEKLPDNVKAIIEDCGYSSVHDELAYQLDDMFSLPAFPL
                     MQVTSLVTKVRAGYFFGEANAVEQLKKNQRPMLFIHGDEDTFVPFEMLDKVYRATKGP
                     KEKYVVKGAEHAEAYKTDPEKYQQVVQQFLSQYVH"
     gene            13907..14866
                     /locus_tag="LLC22_001153"
     CDS             13907..14866
                     /locus_tag="LLC22_001153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000221326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5434443.1"
                     /translation="MTYKHLTIDELTMIESYYLQHNKPVEIANRMGRAIQTIYNVVNK
                     FKQGKTALDYWHQYKENKKKCVRKVIQLPAHEVDYIKEKVTLGWTPDVIIGRKERSVS
                     CGMRTLYRLFSKGIFDIDTLPMKGKRKPNGHQEKRGKQQYQRSIHDRPDNYPDFNSEF
                     GHLEGDTIVGIHHKSAVITLVERLSKVIITIKPNGRKALDIETALNQWFSRFPKNFFK
                     SITFDCGKEFSNWKAISNQHDIDIYFADPGTPSQRPLNENSNGILRRNGLPKSMDFRK
                     VNQTFISSVSNQRNHIPRKSLNYRTPIEIFLSYVQEAFYSSLI"
     gene            complement(14952..16046)
                     /locus_tag="LLC22_001154"
     CDS             complement(14952..16046)
                     /locus_tag="LLC22_001154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK5434444.1"
                     /translation="MGKLGISIYPERSTFEKDKAYLDLAHKYGYKRVFTSLLQINDDK
                     EKVLSEFKEVVDYANSLGMEVMVDINPALFEQLEISYDDLSFFHKMGAYGVRLDIGFT
                     GAEEAKMTRNPFGIKIEINMSSGTNYVDNIMSYSPNTDNLLGSHNFYPHRYSGLGYEH
                     FVFCSEKFRKYNLNTMAFVNSQSAEFGPWPTQDGLCTLEDHRDLEIATQVKHLILTGL
                     IDDISIGNAYASEEELKEMAEAFNADYPTLKVDTEEGITENERICLFDNLHSYRGDRS
                     EYILRSTMTRVYYKDKDFPPHNTRDMHHGDVLIDNEGYGQYKGETQIALKDMKNDGRV
                     NVVGRISDDELFLLDFLKPWSSFKLIENKK"
     gene            16235..16996
                     /locus_tag="LLC22_001155"
     CDS             16235..16996
                     /locus_tag="LLC22_001155"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5434445.1"
                     /translation="MKKNKVILSISLAAALLFAAGCSANNTTSSSSSTESSKSTSTAE
                     STTASSVDLNALELPQLTKDVAENEDLVEMVTNKGTIKIKLFPEHAPKAVENFMTHAK
                     DGYYNGLTFHRVIKDFMIQGGDPKGDGTGGESIWGEGFETEINNHLYNIRGALSMARS
                     QDPNSNGSQFFIVQNTDDMHDGLLKDDYPQAIIDAYKNGGYPSLDGHYTVFGQVIEGM
                     DVVDAIANIETDSSDKPKEEVKIDKINILQEAKQK"
     gene            complement(17111..17551)
                     /gene="fabZ"
                     /locus_tag="LLC22_001156"
     CDS             complement(17111..17551)
                     /gene="fabZ"
                     /locus_tag="LLC22_001156"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBK5434446.1"
                     /translation="MSYVLSATEVMELIPNRYPICYIDYVDTLEPGKKIVATKNVTIN
                     EDFFQGHFPDNPVMPGALILETLAQAGSILILKSEEFLGKRAYIGGINKAKFRQKVVP
                     GDVLKCHFEITKMKGSVGTALSAAYVDDKKVCECEFTFIVNQNA"
     gene            17771..18526
                     /gene="fabI"
                     /locus_tag="LLC22_001157"
     CDS             17771..18526
                     /gene="fabI"
                     /locus_tag="LLC22_001157"
                     /EC_number="1.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="enoyl-ACP reductase FabI"
                     /protein_id="HBK5434447.1"
                     /translation="MSFLEGKKIVIMGVANKKSIAWGCAEAMLKQGAEIIYTYQNERM
                     KKSLVKLVGEEAFTVECDVSSDESIEKAMNAIGEYAGEIHGLVHAVAYANKEELSGNV
                     SDISRDGYQLAQDISSYSLIAVSKYAQPFLAPNSGIVSMTYLGSERAIPNYNMMGIAK
                     ASLEAAIRYLAAEFSPKGIRVNGISAGAIKTLAVTGVKDYQKLIQLSESRTPDQQGVT
                     IEEVGNACAFLISPLSSGIIGDIIYVDKGVHLS"
     gene            complement(18636..19649)
                     /locus_tag="LLC22_001158"
     CDS             complement(18636..19649)
                     /locus_tag="LLC22_001158"
                     /EC_number="2.6.1.42"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid aminotransferase"
                     /protein_id="HBK5434448.1"
                     /translation="MQIDWNNLGFSYIKTPWRFIAKWKDGQWEEGELTEDNYLTIHEG
                     SPALHYGQQCFEGLKAYRRKDGKVNLFRPEQNSRRMNQSARRLLMPMVPEKMFVDAVK
                     QVVKANEDFVPPYGTGATLYLRPLLIGVGENIGVHPAPEYLFVVFCTPVGAYFKGGLK
                     PTNFIVSDYDRAAPKGTGAAKVGGNYAASLLPGTEAKELDYSDCVYLDPATHTKIEEV
                     GAANFFGITKDGKFITPQSPSILPSITKYSLLQLAEERLGLQAIEGDIFIDDLDQFAE
                     AGACGTAAVISPIGGIYHNNNLHVFYSETEVGPVTKRLYDELTGIQFGDIEAPEGWIE
                     VVE"
     gene            19814..20734
                     /locus_tag="LLC22_001159"
     CDS             19814..20734
                     /locus_tag="LLC22_001159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mechanosensitive ion channel family protein"
                     /protein_id="HBK5434449.1"
                     /translation="MFSLLATAGTTDSSGETLTDQAVSKVNAFQRFWDGIDWDAILAA
                     FIQKSLYLIFLIVLFWILHRVGKYLIDKSFNQYSKKAILNESRLKTLHSLLNTIFHYT
                     LGFFFIYAILSAIGVPIGSLLAGAGIAGVAIGLGAQGFMSDVITGFFIIMEQQMDVGD
                     YIKLANLTIEGTVVSVGIRTLQLKATDGTVHFIPNRNITTISNLSRANMQVLLDIRIV
                     PEEGYDKIYEIIDRVNRTLAEKYQEELQTEPSIFGLVDLGNSNFAIRTVCYALNGKQY
                     ALKEEFLSSYVKELTASGFTIPNSPIAVGK"
     gene            complement(21014..21514)
                     /locus_tag="LLC22_001160"
     CDS             complement(21014..21514)
                     /locus_tag="LLC22_001160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5434450.1"
                     /translation="MIGPIVREMLLENQETFLIPAENVANVMYHHPLSHGLLVLSKVG
                     YSKIPVLGKDDHFVGLVSLSDVVNKMIDLQTISMDPLEGLTVADVTETDVPTIDENWE
                     LEEVLHLLVDSPFLPVVTEDRIFKGIITRKELLKAVNFMVHELERRNILSPKIEELKE
                     QIDIVS"
     gene            complement(21621..22139)
                     /locus_tag="LLC22_001161"
     CDS             complement(21621..22139)
                     /locus_tag="LLC22_001161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK5434451.1"
                     /translation="MRYLVVSDNHGDRDILVDLVDRYRSEVDIFFHCGDSELEASDPL
                     WDTFQVVQGNCDYGPGFEQKKVIQTGQDTVFMTHGHLSNVRFGLTQLAIEARAATADM
                     VFFGHTHQIGCEMDQKILFLNPGSISQPRGPIQIPSYALIESLDDQISVQYYNRAHQA
                     VEELAFSFSRER"
     gene            complement(22140..23495)
                     /gene="rph"
                     /locus_tag="LLC22_001162"
     CDS             complement(22140..23495)
                     /gene="rph"
                     /locus_tag="LLC22_001162"
                     /EC_number="2.7.7.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629501.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease PH"
                     /protein_id="HBK5434452.1"
                     /translation="MRHDGRKAQELRKLELQTNVFKYPEGSVVIRFGDTTVICSATIE
                     NSVPPFLRETGTGWVTAEYSMLPRATSTRNRRESSKGKLSGRTMEIQRLIGRSLRAVV
                     DLEKLGERSIIVDCDVIQADGGTRTASITGAFVALKLAIEKLLREKELSEDPIKEHLA
                     AVSVGILPDGTCVTDLDYQEDSAALVDMNLVMTESGKFVEIQGTGEEATFDGEQLNEM
                     LFFGKNAIEDLIKEQKHALLTEFAQNDERIEETKTIIIATRNPGKAEEFRNMFKEAGY
                     HVKTLLDYPELPDVEETGSTFEENARLKAETIAQLLDQPVLADDSGLKVDALGGMPGI
                     YSARFAGEQKSDAGNNAKLLYELTDVPDEKRTAQFHCTLVFAAPKKDSLVVEAEWPGR
                     VARIPSGENGFGYDPLFIPEGKKQTAAELSSEEKNKISHRAQAMKKLSAEWKQWLEGE
                     R"
     gene            complement(23498..24319)
                     /gene="racE"
                     /locus_tag="LLC22_001163"
     CDS             complement(23498..24319)
                     /gene="racE"
                     /locus_tag="LLC22_001163"
                     /EC_number="5.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate racemase"
                     /protein_id="HBK5434453.1"
                     /translation="MIRLTDNRPIGFIDSGVGGLTVVKEALKQLPNENILFVGDTARC
                     PYGPRPAEQVIQYTWEMTDYLVEQGIKMLVIACNTATAVALEEIKAALSIPVIGVILP
                     GTRAAVKKTQNKQVGIIGTIGTVKSQAYEKALKEKVPELTVTSLACPKFVSVVESNEY
                     HSSVAKKIVAETLAPLTTKKIDTLILGCTHYPLLRPIIQNVMGENVQLIDSGAETVGE
                     VSMLLDYFNLSNSPQNGRTLCQFYTTGSAKLFEEIAEDWLGIGHLNVEHIELGGK"
     gene            complement(24481..25137)
                     /locus_tag="LLC22_001164"
     CDS             complement(24481..25137)
                     /locus_tag="LLC22_001164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5434454.1"
                     /translation="MDFSGAFSWMNIRFLLEGLKVTVEVSLFSIIFSFLIGGLTGVIR
                     FANIPFFSKILGVVIDIIRNLPLLLIIFFTYFALPQIGIQMNIFWSAVAALTIFESAM
                     LSEIFRAGLNAVPKGQMEAGLSTGLTYVESMRTIVLPQAFKSMIPAIVSQLISLIKDT
                     SLAVIISLPELSHQARIIYGQNTNYVLPMFIIMTLMYFVVCYALSLLSGYLEKRRYSY
                     "
     gene            complement(25153..25800)
                     /locus_tag="LLC22_001165"
     CDS             complement(25153..25800)
                     /locus_tag="LLC22_001165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5434455.1"
                     /translation="MSELIQTYGPIFVDGFKITLFSSVLALVFSLIIGTLMAIFQLSK
                     NKVVSALAKAYVEFFRNIPLLIIVMFFYVVVPIYWFNLDGFQAGTIGLTIYTSAFIAE
                     TVRSGIQTVPKGQTEAGLSSGFTYSEIMRYIVLPQAFKIVIPPLGNQFINLVKNSSIL
                     AIVAGLDLMYQGDLIASETFNTFDTYIIVGLFYLVITLPLSYLMVYLEKKWAVRS"
     gene            complement(25813..26628)
                     /locus_tag="LLC22_001166"
     CDS             complement(25813..26628)
                     /locus_tag="LLC22_001166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBK5434456.1"
                     /translation="MRRLKKIRLIFLLGIAFLALAGCKGNGLANEDILERSKSTNEII
                     WGVKYDTRLFGMMDIESRTVQGFDVDIAKAITKKILGDNGKTEFVEVTSKTRIPLLKN
                     GNIDAIIATMTITDERKKQVDFSDVYFDAGQALLVKKGSQIKSVDDLNASTTVLAVKG
                     STSAANIRQHAPDAKILELENYAEAFTALQSGQGDAMTTDNAILLGIADENPEYELVG
                     GTFTNEPYGIAINKGQENFLKAVNQALEEMHADGTYDKIYQKWFPNETEGKVE"
     gene            complement(26642..27379)
                     /locus_tag="LLC22_001167"
     CDS             complement(26642..27379)
                     /locus_tag="LLC22_001167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5434457.1"
                     /translation="MAMIKFDHVDKYYGKFHALKNINLEFEKGEVVVVIGPSGSGKST
                     MLRCINGLETISSGKLLINDTDLHDKKTKLTEVRKNIGMVFQHFNLYPNKTVLENIKL
                     APIKVLKQDQATAVKNAEKFLKTVNMLDKKDSYPSMLSGGQQQRVAIARGLAMNPEML
                     LFDEPTSALDPEMIGDVLDVMKKLAHDGMSMIVVTHEMGFAKEVADRVIFMADGEVLE
                     DSRNVRDFFENPNEVRAQQFISKVINH"
     gene            27633..28643
                     /gene="trpS"
                     /locus_tag="LLC22_001168"
     CDS             27633..28643
                     /gene="trpS"
                     /locus_tag="LLC22_001168"
                     /EC_number="6.1.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan--tRNA ligase"
                     /protein_id="HBK5434458.1"
                     /translation="MKNIILTGDRPTGKLHLGHYVGSLKTRVAMQADEDNQLFVMIAD
                     MQALTDNAKNPEKVSSNVLQVALDYLAVGLDPAKSTLFIQSQIPELAELTMYYLNLVS
                     VGRVRRNPTVKTEIEQKKFGESVPTGFFIYPVSQAADITAFKANLVPVGEDQKPMLEQ
                     TQEIVQSFNHTYGEVLVEPKGVFPPKGMGRLPGIDGNGKMSKSLGNGIYISDPADVLQ
                     KKVMSMYTDPNHIHVQDPGQVEGNMVFTYLDVFGTDKEAIEEMKAHYRRGGLGDVKIK
                     RYLIDVLEAEFAPIRARREELEKDPSAVMEILRKGSEEAAKVAAQTLSEVKSAMGINY
                     FH"
     gene            complement(28813..31233)
                     /locus_tag="LLC22_001169"
     CDS             complement(28813..31233)
                     /locus_tag="LLC22_001169"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit beta"
                     /protein_id="HBK5434459.1"
                     /translation="MLVSYKWLNRYVDLSNVTPKELADKMSVTGIEVEGVTVPEEGLK
                     KIVVGEVKECVPHPDSDHLSICQVDIGEDELSQIVCGAPNVKVGIKVIVALPNSRIAG
                     NVKIKKGKMRGQVSNGMICSLQEIGYSDSVIPKEYAEGIYYMPQEAVNGDPVFPYLDM
                     DDSIIELSITPNRADALSMRGVAYEVGAIYRQTPTFDDEKLVESSRPASDKIQVEVED
                     KEAVPAYQIRIIEGVRIQPSPQWLQNLLMNEGIRPINNVVDVTNYILLLFGQPLHAFD
                     YDKLKSKEIFVRRAKENETLVTLDGESRELTTDNLVITNGKEPVALAGVMGGLDSEIT
                     NETTTVALESALFDPISIRRTAKQFNLRSESSARFEKGINHATVGEASEVAAAMIVSL
                     AGGEVLQGAVKGSEIKAEDVSVKISLERINQYLGTSLVVKEVNEIFEALGFSYEEKEY
                     VYSVVVPPRRWDIQIEADIIEEVARIYGYDQLPSTLPSGETVAGSLSKEQETTRKIRT
                     IFEGSGLSEAISYALTTEEKSRQFVINESNITRLDWPMSEERSVLRMNLISGLLDDIS
                     YNTARKNTEIALYEIGRVFFQENDPRTHLPQEVKHAAIAISGIWEEKDWQTKAQNVDF
                     FTIKGLLENLFEQLGITEDVHYQTVTEMKEMHPGRTAAIYLGEKFIGFVGQVHPTITK
                     SYDIPETYVAEFDLSAIVEAAQKGIVFEAVTKFPAVSRDIALLVKETVTNQELTEVIR
                     SAAGRFLTDIQLFDVYQGENIEKGHKSMAYSLTFVNPEATLTDEEINKAMEKVEKALV
                     ENLEASIR"
     gene            complement(31238..32281)
                     /gene="pheS"
                     /locus_tag="LLC22_001170"
     CDS             complement(31238..32281)
                     /gene="pheS"
                     /locus_tag="LLC22_001170"
                     /EC_number="6.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanine--tRNA ligase subunit alpha"
                     /protein_id="HBK5434460.1"
                     /translation="MSLQAQLESLKEATLVKITAAQDLNELNQIRVETLGKKGPITEV
                     LRGMKDLSPEERPKVGSFANEIRDLLTEEIERKKQVLEEEALNAALAKETIDVTLPGR
                     KVKHGTRHIVTQIMEEIEDIFVGMGYQIVEGYEVESDHYNFERMNLPKDHPARDMQDT
                     FYISDEILIRTHTSPVQARTMEKHDFSKGALRMISPGKVFRRDTDDATHSHQFHQIEG
                     LVVDKNITMGDLKGTLEVVMKKMFGEDREIRLRPSYFPFTEPSVEVDVSCFKCGGAGC
                     NVCKYTGWIEILGAGMVHPNVLKMSGIDPEEYSGFAFGLGPDRVAMLRYGVNDIRNFY
                     QNDLRFLSQFKGE"
     gene            complement(32590..32931)
                     /locus_tag="LLC22_001171"
     CDS             complement(32590..32931)
                     /locus_tag="LLC22_001171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5434461.1"
                     /translation="MELTQTEFVLCPKFEKTFSILGKKWNGLIIDVLLENGPQRFVEL
                     AAKIPMVSDRVLVERLKELEKEGIVTRNFACSEKSRSEYLLTEKGADLQKAMRQIQVW
                     SEKWITEEECG"
     gene            complement(33000..36722)
                     /gene="addA"
                     /locus_tag="LLC22_001172"
     CDS             complement(33000..36722)
                     /gene="addA"
                     /locus_tag="LLC22_001172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helicase-exonuclease AddAB subunit AddA"
                     /protein_id="HBK5434462.1"
                     /translation="MNQIPLKPQNERFTDDQWQAIFDQGDNLLVSASAGSGKTTVLVR
                     RVIEKLKMGFDIDELLIVTFTEAAAREMKERIQEALQESVNSESDPVRRQHFTKQLVL
                     LPTANISTLHAFCLTVIRRYYYLIDIDPVFRMLTDETETILMKEDVWDELREALYAEN
                     DERFFQLTMNFSNDRSDDGLTNLVFSLYEFARANPDPQKWLEQLSDNYRLPEGLAKSR
                     LYQKQIRPLVLADIYQCVQLYEQMTQLAQGEGLEKMHEQVAGEQQQIKNIYEAFSQDR
                     LEEAYAGLEQLTFSTFKSSRKAELKEISNEVKGMRDKAKKLIQQISKSYFPVSPSQME
                     ELTDKALPLVEEMTKVTQSFMDGFSMRKREKGVLDFNDLEHLALQILTEKTKDVWLPS
                     EASKHYRKKFKEVMVDEYQDVNQLQEAILYWLREPDDTKGNMFMVGDVKQSIYSFRLA
                     DPSLFIGKYENFSKKEGGRRIVLAENFRSRKEVLSFTNLIFEQLMDPAVGQINYDEAA
                     KLIQGFSDFPENEQFEPEIMIYEKEQEESEIEIPTDDILEDKTEGELFMTGLKIRQLI
                     DSSFMIYDKKSKKSRPIEYKDIVLLTPTKKNNLTILEIFKTLDIPLEMNDAQNYFQAT
                     EIRTMISLLQLIDNPYQDIPLAAVLRSPIVGLIEPELASIRLANRAHTYYDAVLAYQA
                     SNEDELAAKLEHFGKQLEHWRELARRSSITDLLWDIYYETGYLEYVVGLPAGAQRQAN
                     LYALVDRAKAYEQSSFRGLYQFVRFIEKMQEKDKDLAEPVISIEDNAVRVMTIHASKG
                     LEFPVVFLLDMTKEFNLQDLRNRYAFEEKLGAGIRYMDPETRVLYDTLPFQAIKLAKQ
                     NKLLSEEMRKLYVGLTRAEQKLFIVGSYKNKEQMIQTWSEAADHEELVFDPALRLKGR
                     SSLMNWIGYGLIRHPEMQKYLEEEISTSFLQHSNAQFSISWMNQQSIIEQRQLLAEKE
                     LVNLDQQMKEDETLLADSLQKRLAYEYPYQASSQTTSYQSVSEIKRLFEDPDDTQESR
                     LTLESSQNKAASRQFRYTQEQLAEPKFLQKDRQVSAAAVGTATHALLQLLPLEMPTTE
                     SIHQKLQELVRKRLVDEKVAKKVDVSSIIWFFQTELGQQLIANKENVKREQPFSMLLP
                     ADEVFQDYPNQEDELLIHGIVDGYLEEKDHLNIYDFKTDFILHPDDPAEIDAIVQKYQ
                     GQLRLYQQAMSEALNKPVENVFLILLRVKQIININK"
     gene            complement(36719..40246)
                     /locus_tag="LLC22_001173"
     CDS             complement(36719..40246)
                     /locus_tag="LLC22_001173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PD-(D/E)XK nuclease family protein"
                     /protein_id="HBK5434463.1"
                     /translation="MSLQFILGNGKKDHRQVLIDEASAWLDQDASNQVFFLVPNYSKF
                     EQEQEILAEMRRRSGKKTFSTTNVQVFSFYRLAWYLLQQTTLLTGNELSESGSAMILR
                     QILEKNEEELTIFRGEINKRGFIRQLQELYSELRTGNIQPEDLMLLFGDSPNAEDQQL
                     KMKDLKLIFSAYDSELTQRALTNEDALSILANYMQTQDFNNVKFIVSGFSRINGQEYQ
                     LLQAMMEKGQLVVDLLLDRPYTADLPEVLTLFHETGKLYFRLFQSARERKVPILVDRF
                     APEQTRPTELQLLQTMWEETSSQKKAAVHKIGGQEHLHLWEAENPTEEVRQLAVEIRR
                     LVSEENYRYRDIQVLTKNMSLYGNILRPIFQEMAIPFYIDEEQMMENHPLIEWINSLF
                     ALDRYSYRLSDIMRFFKTELFLSTEAETELDEWKQERDEFRKKLDITENVALAYNYQG
                     TYWTREKDWQFVAYDFEAEQIEDVQYLEEQSNTIRRLFQKAVPVFLKKIKKSKTGQEA
                     ANVFYQFLIQSGVQQQLLFWRNQEVDRGNLEAARNHEQTWGALIDLLDEYVVIYGESA
                     FDWSLFQEIITSGLENLSYGKIPTAIDQVRINRLELVRPNQAAVTFALGLNDQVFPDR
                     KETKGLLSSEEREVLNQALPDGQFLFDPSKESISFEPFQAYLVFLSGTDRLYLSYAQS
                     YDTDGSLKMSPYLRRITEYLSVPVERKEHLTIESDPNCYVGTYRSGINTVNRIYRLAL
                     DEKKPVPKHWQKLKELVLNSSWRNFALQIFESQEHLNVPVSMPEKMAEELYGKEIYTS
                     ISRMENFYNCEYKYFMQFGLKLKERTVYGLTPAATGDFYHESLDRFFKLLFSNQLSLV
                     NMSDAQRRDFTEKVLQEVFGELRFEILDSSARMNYIRYQLGQTIQKVTWALQKQSKNT
                     GMHPLQTEILFGQIAGAKGITGLELPLSNGGKLHVRGKIDRIDVASEQEDTWLSVVDY
                     KSSGRSFDVTEAYYGMAMQLLTYLDVALMDAVRLTGKAAVKPAGSYYLHVHNPVLTET
                     DDVEKNTLKKFSYDGVFVDDPALLEVLDHSLEAKEQSLIYPVKKNAKDEYQKGSFSKD
                     KFFTEEELQLFMAHNRENMRLAGDAITSGEIKLNPAYKDKQRIACEFCPFRSICTFDV
                     MLKENNYHRLEKIDKEEALRRILKRSEEE"
BASE COUNT        11438 a         8670 c         7043 g        13221 t
ORIGIN      
        1 tctcaagaaa cacaaactaa tccgaagaat tctttgtttt gtcatttaaa tgtaacatag
       61 ccgaaaacga aaagtaatat tgatttattc ttctaacaca taaagaacag ctgtctccaa
      121 cttgcagaca gctgttctta tcagtcaaac aattgcttgg atctatgata gttgattgta
      181 cgtattcacg acattttcta ctgtaaatcc aaattcttct aaaattttag tgccaggggc
      241 agatgcaccg aaatgatcga ttgtaatcgt tgcgccctct gttcctacgt agcgttccca
      301 tccaaatgat gcagcagctt cgatagccac acgtttcttc actgatttag gaagtacact
      361 ttctttatat tcagaagatt gtttttcaaa gaggtcaaag cttggcatag aaacaacaga
      421 aacatctttg cctttttcag ccaattcttt ttgagctttc acagccaaat caacttcaga
      481 acctgttgca atcaaaatac cttctggtgt ttctccttgt gatggagaaa gaacatacgc
      541 gccttttttc accatttcat ctgctacttc ttttgtagaa ggcaatactg gaaggttttg
      601 acgactcaat acaaggatag taggcgcatc tgttgtctcc atcgctactt tccaagcagc
      661 acgtgtttca tttccgtctg ccggacgaat cacttgaaca ccaggcatgc agcgaacaga
      721 tgctagttgt tcaatcggtt cgtgcgttgg tccgtcttct ccgacagcaa ccgagtcatg
      781 tgttaagacg taaacaacag gagtatgttg gattgctgct aaacgaactg ctggtcttag
      841 ataatcgaca aagacaaaga atgttccacc gtagatacga gttccgccat gaagttggat
      901 accattcata gccgaagcca ttgcaaattc gcggacaccg aaccagatgt tgcgtccttc
      961 ataatgttca ggagtgaaat ctttatctgc agccaccatt gtattattgg aacctgacaa
     1021 gtccgctgaa ccaccccaga agcttggtat agctttcgat aattcttgga tgacttcttt
     1081 acttgaaaca cggcttgctt gactgcttcc aacttcataa gttggcaatt ctgcatccca
     1141 gttttctggt agtttgccat caaaagcatc ttcaaattgt tgtgctaatt caggataagc
     1201 ttttttataa ttggcaaaca tttcattcca tgcatcttca gctttttgtc cttcttctat
     1261 catcgtttga tggaagcggg cagctacttc ttctggaaca gtgaaatctg gatactccca
     1321 accataaact tctttagcca tcttgatgcc atcttcacca agaggagcac catgaacagc
     1381 agatgttcct tctttaggag caccatagcc gatgactgtt tttacttcga tcaatgttgg
     1441 tttgtctgtt tcagcttttg cttcttcaat cgctttagag attgcttcta ggtcatttcc
     1501 gtctttcact aagatatgtt gccagccata tgcttcatag cgagcaccaa cgttttctgt
     1561 gaaagctttt gaagttggac cgtctagtga aatatcgttt gaatcgtata aaacgatcaa
     1621 tttccctagt ttcatatgac ctgccatcga acttgcttct tgagataccc cttccatcaa
     1681 gtctccgtca ccgcatattg catacgtata gtgatccatc acattaaagt tttctttgtt
     1741 atacgttgct gcaaggtgcg cttctgccat tgccataccg acagccattg caatcccttg
     1801 tcctaatggc cctgtagtgg cttctacacc atctgtatga tgtacttcag gatgtcctgg
     1861 tgttttagaa tcccattgac ggaattgttt caaatcatcg attgtcactt gatagccagc
     1921 taaatgaagc aagctataca acattgctga cccatgtcct gccgaaagaa cgaaacggtc
     1981 gcggtcagcc cagttttttg atgtcgttgg atttactttc aggtgttttg tccataacgc
     2041 atatgccata ggtgctgcgc ccatcggcaa tccaggatgt cctgagtttg ctttttggac
     2101 tgcttcaata cttaatgtac gaattgtgtt aacgccaagt tggtcaattt tgtcaaacaa
     2161 aataacccct cctattaatt taggtttttt ttacctttat ttcttacact ttcattctat
     2221 aagatgtcac acgaaaaagc aatctttttc agtatttttt actaaaagtt gtcatttcgg
     2281 ttgtgtaagc cttttttctt ttggatttct tttaattttt ccggggtcac gtcattgccc
     2341 tcaggatcga cgactttcat tccttcgata tgatgacgca taccggaacg aaaagcttcc
     2401 aaatactctt tgcgcaagtt gatttgttct tgttcttcgg cttttgagag accattttcc
     2461 ttctttttac gtgcaagttc attgatccgc tctatttttt caggtgacag catgctcagc
     2521 cctcctttta ctctccttca tattatataa aaactgaaaa aaaaacaact agataaacta
     2581 aataaaatac gaacattcgt ttgatttagc gctttttata tggtactatt tatttatcaa
     2641 gtgaaagaag gtgtaccttg tggcccgaca aactgaatca agacaaatcg aagtcttacg
     2701 atatatccat gaacaagtaa cccaaaaagg atacccgccg actgtccgtg aaatcgggga
     2761 agctgttcag ctttcttcta cttctactgt tcacggtcat cttgcacggc ttgaaaaaaa
     2821 agggtttatc caaagagatc cgacgaaacc tcgtgcaatc gagttgacaa aacaaggttt
     2881 agaaaagatt gggattcgtc caacaactat tccagtactt ggcgtcgtaa cagctggaga
     2941 acccatttta gcagtagagg atgcttcaga cttctttcca atccctccta atctttcttc
     3001 cgaagaaggc agtctcttta tgctgacaat tcgtggagat agtatgatca atgctgggat
     3061 attggatggt gacaacgtga tcgttcggaa gcaagaaact gctcaaaatg gcgatattgt
     3121 cattgcaatg actgccgagg acgaagcgac ttgcaaacga ttctataaag aaaaaaactt
     3181 tttccgtctg cagcctgaaa acgacttgct cgaaccaatc atcttagatc aagtatctat
     3241 attaggacga gtagtaggac tttatcgtag tcatatctat taattgctac taattaaaag
     3301 aaaacttttt aaaaagagtt tgagacgttg gtctcaaact cttttttcgc ccgggttctt
     3361 cttctttcaa atttttatca cttccctctt tacaaaccga acaaatattc gtatactaaa
     3421 tatacgaaca attattcgca taaattaaag aggtgagaat tcatgaaatc aatgagacgt
     3481 cttggcttag tattaactgt tttgttttta ggtattatta ttggtaattt cggcatacgt
     3541 ccagctttac ttgtgtttgt tccgttattt actttgtggt tcatgttgtg ggatgaaaag
     3601 aagtaccgtc aatctgagcg gcgcagaatt catgaagatc atttctatca tgagccctac
     3661 tacagatcca ggcaatcata ataaggattg actgctaatt attcaaaaga caagaagtta
     3721 aacttttacg ggggtgtgac aaaaatcggt cacatccttt ttttcgaata aacggtgttc
     3781 taaagccagt ttttcggtat taagtcaaat tgcggaaaaa gtgatttttt aaacttctac
     3841 tggtctttgc ttgtttccat ttataaaaaa atagcgaccc tcaaaagtca gatagagaat
     3901 ctgacttttg agggtcgctt taaaatcgct tctttaagaa taacatcaag aatagcttct
     3961 tttttctgct taatattcca ttaatgtaat gatgtcatat cctttgattt tgtcgcgtcc
     4021 atggagatcc atcaattcga tcaaaaatgc gcagcctacg actacaccgc ctaattgttc
     4081 gatcagttcg atcgtcgctt tgattgttcc tccagtagct agcaaatcgt cacaaatcag
     4141 cacacgttga cctggtttaa tggcatcctt atgcaatgtc aatgtatctg ttccatattc
     4201 taatccataa gtcacttcga tggtttctcg aggtaacttc ccttttttgc ggactggggc
     4261 aaaaccgact cctaactcat aagcaacagg acatcctacg atgaatccac gggcttctgg
     4321 cccaactacc atatcaattc gtttttcttt tgcataattt acgatttgtt tagtagcttc
     4381 ccgataagcg tcaccatctg ccatcagtgg ggaaatatct cgaaacacaa ttccttttga
     4441 cggatagtcg ggaatactgg caatataatc ttttaaatcc actctttgtt tcctcctagg
     4501 ttgttaacca tttctttatg gtaggaatat cgctcaaaag caaaaattcc tcaactttga
     4561 ttttattgag ccgtcgctgg tataatctgc tctcagtcaa aggatgactt tctgggctag
     4621 cgactttttg taaaacaccg ttctctattg taacaaattt caattcaaaa aacacctgta
     4681 tcataaaaat taataatttt tcagggatac gcaaatattg agctattgct tttattttat
     4741 gacgtatatc aattcgttct tgagaatgga tcaatttaaa caattttgcg tactgttctc
     4801 ttgtgcctac cccattcaaa taggcctcat caggtgaaat ccccatcaga taaacacgat
     4861 tgaatgaata agaccgaaaa acttctttca gatccgctaa atcatctgga caatccataa
     4921 caactagaga gtttggtttt cttttttcaa ttattgcctt tacagaatct agtccttcga
     4981 aaacaatcgc agcttcctgg ataatctcag gcacgaattt caacgtcgaa gaatcaaatg
     5041 ctaaataaag gctaccttcc gacgttcggc tctgttcacg gaaacgtttt gcccgccaat
     5101 caaatacttg cagaccaccc acagaaaaat cagataccat cagctgcggt ttcttacgcc
     5161 cgttccattc attgatcgaa agctttccta ccacatctac ctgattattc agcagttctt
     5221 cttcttgagt accaaaacca aaagcgaccg catcaagctg actcgatgca tcggaaagga
     5281 caaatttcag atgctgttgg tttgctccga ttcttttgat attttctgct tggacttgtc
     5341 gaaataaaaa ctgaggcaaa ggattatccg taccaaatgg cgccaatagt ttcagctcat
     5401 caattcgctc tactgttact tcatttggca gcaatacttc atcaattctc aactcaggcc
     5461 ctctcatcaa gtcaatttga tgatcgacta tatattggtt catcttctcc tgtagtatag
     5521 tgacattttc acttggcatc gttaaaccga ctgctgcatg atgtcctccg aagtaagtaa
     5581 ataaatctcg catctggtca agcatttcaa aaagattcaa ggcttcaata ctacgtccag
     5641 atcctttagc tgatccatct tcttttaaag taaggacaag cgttggttta cccgtttcat
     5701 tcattatttt cccagcaaca atgcccaaaa cgccttcatg ccatcctcgg tttaccaata
     5761 gatggatatg attctcctta ttgaccatcg ctaatgcttc ttgtgttatc tgctctacga
     5821 ttgcttttct ttcttcattg atctcattca atttttttgc ttgaacggat gcttcctctt
     5881 catcaaacgt cgcaagtaac gagacggcag gacgtggatc gcccatccga ccgattgcat
     5941 ttagtctggg agcaatcgaa aaaccgatcg ttgtttcgtc tgcgtccctc atttttacgc
     6001 cgctttcttc aaatagcgcc tgaagtccta tccgttctga atgatgaatg gcatcgattc
     6061 ctaatgaaac aaggattcga ttctcatcag tcaatgaaac taaatcggcg atcgttccta
     6121 tcgctactaa atccaaaaat tctgcaggcg gttcttccaa taatgcagaa gctactttga
     6181 atgctactcc gactcctgcc aaatctggaa atggatagtg ccccgctgga tgacgagggt
     6241 gaacaatcgc ataagcgtct ggtaaattct caggtagttc gtgatgatct gtaatgatca
     6301 cgtctacacc agcttgctga gcgtatgcta ccgcatcatt tcctgctacc ccgttatcaa
     6361 cagtgatgat caactggatt ccttcttcga tcttttcttg gtataccgat tggtttggtc
     6421 catacccatg ctcaaatcga tttggcagga atacttctac ttctgcacca agtaattcca
     6481 gtgtttcttt cattaccgtt gcactggtga tcccatctgc gtcataatca ccgtaaacga
     6541 ggattttttc tccactgatt acagcttctt ggattcggct gattgcttta tccatatcgt
     6601 gtatcagata cggatcatgt aattcttgtt cctttggatg taaaaatcgg ttgatatcct
     6661 tttcctcatg gtaacctctt tgccacagta acttaccgac aaatggagat aatttcagtt
     6721 cacggatcat ttggagaaag gattcagaag gctctgtctc gcttaacttc caatcaaaat
     6781 ttgcttgtct cactttctca ctcctaactt agttattata gcaaaggaaa tcagcaaaaa
     6841 aaagcagaaa gaaagaataa aaacagatca gatccgctag acagatgttc agcaggacct
     6901 gatcttttgt acgaccattt atgaaatatc cctattagtc aaaataattg aagctttgtt
     6961 tgggcgattg agttttttgt tcttccggcg ctttcaattg actgatttgt gcggttttcg
     7021 cttgtaactc cgcctgataa gcagcttcca actccgcacg ttcgtttcta aactcgcgtt
     7081 gctgttcttc ttttgcttct tcaattttct tttgaagttc tgtttgatat tctgacattt
     7141 cctgagtcag ctgtttgatt tgcttttttt gctgccatag tgttgccgaa gcagtcaaaa
     7201 atacaatcag tgcaccaatc agcgcagaac cgatgatcac taagatcaat ggcgcagaaa
     7261 aggaagtgaa gccaaaactt acaggaacat ttttattgtt caatacagca aaaagaacaa
     7321 taatcaaaac taaaacaaat ccaagaatca cattgctttg ctttttcaat tccttcacct
     7381 actttttgtt aaaaattccg ctggctaaat aatcaccaat cgttggaaac agcgtataaa
     7441 attttgatgc aacttctaaa ataaacggtt gattgatttc ccgttttgga tgtctcatat
     7501 tgcggacgat catttttgcc aacttggcag gttctaaaac gatttgtccg actttttcca
     7561 aatagcttcc gcttggatca gccttatcga agaaatttgt ctcgattgga cctggattca
     7621 ctgtcgtaac agctacgcca agtggtttca attctaatcg caaagcgttg gagaagccaa
     7681 ggactgcaaa tttcgtggca gaataaaccg ttgattttgc agttgccatt tttccagcca
     7741 tagaggcgat attaatgata tgaccttgtc ttctttctgc catatcgatc gcaaattttt
     7801 gtgtcaaaac catcattcct aagatgttga cttcaaacat atcgtatgct tttccaaggt
     7861 cgaatgtaag gaagtcttcg aaaatcccaa aacccgcatt gtttaccaga atatcgacgc
     7921 gcccgacttc ttccatcacc ttttcatata attcgtccac gctttcagga ttgctgacgt
     7981 ctaccttgaa agcataagcc tctttgccgc tcaagcgtct gcactcgtct ctgacacctt
     8041 ctacaaatgc cattcttcgt gcgcaactta taacgattgc tccttgcttt gctgcttcat
     8101 aacagatttg tgcgcccaga ccgcctgaac tacctgttac taaaacaact ttatcttcta
     8161 aattcatgcc tcttcctcct cgcgaaatgg aatctcaatg ctatcaaaat ctttcataat
     8221 cgtcgtgttt tcaaacactt cttgtgcttc tttttcaagc tctaaagctg cttttcctaa
     8281 atatctcgca ctgatatgag taagtagcag ccgttttgcc tgcgcttctt ttgcaacttc
     8341 agcagcttga tgagtcgtgg aatggaaata gttgtgcgcc attcttgctt catctttatt
     8401 aaatgtgctt tcatgtacca gaatatcgct attttccgca agcacaacgg aattatgtgt
     8461 ttttctcgta tcgcctaaaa tagtcacgat tcgtcctttt ttatctggac ctacgaaatc
     8521 ttttccattg atcgtccgcc catcttctag ttggatcgtt tcaccttgct tcagtttgcc
     8581 gtacagtggt ccagctggaa tacctaattc ttttagacga tccacctgca attctccttt
     8641 atgatcatgt tcaaccacac gataaccaaa actgtcgatc ccatgattta gtttttttgt
     8701 ataaacagaa aattgctgat cagtaaaaat cggggctgtt tcatttagct caatgaattt
     8761 cagcggataa cttaaacgcg tttgcgaaat acctaaagag acttttatgt attcctctat
     8821 cccttttggc ccgtaaatct ctaatggcgt atccccacct tgaaatgacc ggctgctgat
     8881 gagcccggga agtccaaaaa tatgatcgcc gtgtaaatgt gtaatgaaaa ttttaccgat
     8941 ttttctcgga cgaatagtcg ttcgcaaaat ctgcatttgc gtgccttcgc cacagtcgaa
     9001 caaccaaact tcattgcgct cgtctaaaag tttcaatgct atacttgtca catttctatg
     9061 ttttgcagga acacctgcac ctgttcctaa aaattgtaat tccataatct acctgacttt
     9121 ctttaagttc ctctttaatt ttagggtaaa aagaagggat aatcaaccgt aagtcgagaa
     9181 tgggttcaaa ttaaaaataa cgttctaaag cgatagcgtt ttctttgaaa attactataa
     9241 aaacagcagc gaacccgttt gagatcctct gctgtttttt attaatttga agatccagaa
     9301 ctttcattgt cgttggaagt ttgcggatgt ttgtccttcc aagtcttttg tgcagcttct
     9361 ttcgcatgat tttcagcttc tttcgcatca tgcacatctt tttcgacatc ttcataatcc
     9421 aagcgagtaa tttctccgcc taattccatc attaccaatt gattcagtgg gcgattgtcc
     9481 tcttcatcag caatcaagat cagtcctgta gctccttcac cgattttatt tcctacaaag
     9541 tcgaacacgg tctgggcatc ttttatttct ttggcatctt gtgtcgcacc gatcattcct
     9601 ccggcaaacc atcctaataa aatccctagc ggaccaccta atacaccaac caacattccg
     9661 attaatccac ccgtagaaga tttgttatta ccggtaaagt cgataaaatc ttctattttg
     9721 aattgatgtg tcccattagg atcatggctg acaactgcca tctgttctcc tttaatcgaa
     9781 cgaacagcat gtaacttttt gatttctgaa aatgcctgat atgcctggct ttctacttga
     9841 aaatttaaaa tgattactcg tttgctcatt aaaaacgccc ctttcatacc ttcttgttat
     9901 ttattttacc tttaattgaa aaataagaaa agaaaagcac tctttttttc caataaaata
     9961 gggctgtgac aaaagtcgta tcacagctcc tttttccgaa taaacggcgt tcttgaagct
    10021 gatcacttct gtcacaacct cccttaaatc tgaatctata ttttttggta tttgttttta
    10081 tttgcttgcc tattcgacaa attcaaattc aaactcaccg atacgtacaa ggtcgccatc
    10141 tttcgcaccg cgtgcccgaa gagcttcatc cacacccata ccacgtaatt gacgagcaaa
    10201 acgcatcact gtttcatcat gatcgaaatt cgtcatttgg aataattttt cgatcttctc
    10261 accagataag atccacgttg catctgaatc acgatcgatt tggaactcag gaccttctgg
    10321 attgaatcca tagtgtacag tttcttcttc cagttcttct tcgtacaatg ggaattctgg
    10381 cgttacttct aacaaatctg ctgtagcatt caataacgcg tccaatcctt gtcgagtcac
    10441 tccagaaatt ggaaatactg ggatgtcatc agcaaattca tcttcttttt ccttgttcag
    10501 ctgttctttg aatttcacta gattttccgg tgcatccggc atatccattt tgtttgccac
    10561 gatgatttgc ggacgctcta gcaagcgtaa gttataagta gataattctt tgttgatggc
    10621 aagatagtct tcataaggat ctcgtccttc catcccactc atatcgatca catgtaaaat
    10681 tactcgtgtt ctttcgatat gacgaaggaa ttgtgtaccc agcccaacac cttgcgaagc
    10741 tccttcaatc aagcctggca agtctgctgc ggcaaaactt ctgccatcac ttgtagtaac
    10801 cattcctaga ttaggtacga gcgtcgtgaa atgataagcg ccgatttttg gacgagcaga
    10861 tgaaataacg gatagtaaag tcgatttccc gacagatgga aaacctacaa gtccaacgtc
    10921 tgccaatact ttcaattcta gttcgatttt tcgctcttgt cctggttcac cgttttcagc
    10981 aatttccggt gcaggattcc gaggagaggc aaaacggata ttccctcgtc caccgcgtcc
    11041 accttttgcc acaactagtg tttgaccatt ttcaattaaa tctcctaaaa gagcaccagt
    11101 ctccgcatct cggacagtgg ttccttgtgg tactttaaca taggtatctt ctgaaccacg
    11161 accgtgcatc cctttactca tcccattttc acctggctgc gctttgaaat ggcgattgaa
    11221 ccgaaaatcc atcaatgtac gtaacccttc atcgacgatc aagatgacat cgccgccacg
    11281 accaccgtct ccgccagccg gtccgccgtc aggaacgtat ttttcgcgac gaaatgcaac
    11341 cattccgtct ccgcccttgc cagctttcac atcgatcgtt acttgatcta aaaacatgga
    11401 cataattaag tcctcctatt attcatttat ttatttgact gcctgaattt ccacaataaa
    11461 caaaagtctt acttatttta tcggtgaaat ctgattttgt ctatcatttc agcaaaaaga
    11521 ttgtttacct tcttcttttt ttatcatttg gtaaggtttc caaccttttt tctgctacca
    11581 agtataattt tttgacaaaa tattctttgc gtagcagaat aacagtgtat taattgtatt
    11641 aattgaggat gccgtttcac agcaccccta ataaaggagg aacttttgat atgacagtaa
    11701 aagtaggtat taacggattt gggcgtattg gccgtctggc tttccgccgc atcaaagaag
    11761 tctcagatga tattgaagta gtagcaatca acgacttaac aagtccaact atgttagcac
    11821 aattattgca atttgactct actcatggta cttatcctgg cacagttact gcaacagaag
    11881 actcaatcgt agtggatggc gaagcaactc gtgtttatgc agaacccgac gcaagcaaaa
    11941 tcccttgggc aaaagaaaac ggtgtagata tcgtactaga atgtactggt ttttatacat
    12001 ctgaagaaaa agcaaaagcg catttagatg ctggtgtcaa acgagtagtt atttctgccc
    12061 cagctggtgc tatgaaaacc atcgtctata acgtcaatga tgatacatta gatgaaaacg
    12121 acaaaatcat ctcagcaggt tcatgtacaa caaactgttt agcacctatg gcttatttct
    12181 taaataatga atttgggatc gaagttggta caatgacaac agttcatgcc tacacttcca
    12241 cacaaatgct cttagatgga cctgtaaaag gcggtaattt gcgtgctgct cgttcagctg
    12301 ctgacaatac tatcccacat tctactggtg ctgcgaaagc aatcggctta gttatccctg
    12361 agctacaagg aaaattacaa ggacacgcac aacgtgttcc agtcgttgat ggttcattaa
    12421 ctgaattggt ttcagtattg aaaacaaaag taactgctga tcaagtaaac gaagcaatca
    12481 aaaaacacac agttgacaat ccttcattcg ggtatgatga ccgtcaaatc gtttctagcg
    12541 atgtcattgg aacaactcaa ggttcgatct ttgacccaac gcaaacagaa gtaacaactg
    12601 ctggtgattt ccaacttgtt aaaactgttg catggtatga caatgagtat ggatttactt
    12661 gccaaatgat tcgcttacta gaaaaattcg ctaacttgta atttgataga tcaatcgata
    12721 aaagaagcct ttgactggat ccagtcaaag gcttctttct tttcatcccc tacttttaaa
    12781 ctcgttcaat gaacatattg gcttaaaaat tgttggacta cttgctgata tttttcagga
    12841 tctgtcttgt atgcttccgc atgctcggct ccttttacaa catacttttc ttttggtccc
    12901 ttcgttgcac gatagacctt atctaacatt tcaaatggta caaatgtatc ttcgtctcca
    12961 tgtataaaga gcattgggcg ctggtttttc ttcaattgtt ccactgcatt tgcttcaccg
    13021 aaaaagtagc cagcacggac ttttgtcact agactcgtta cttgcataag cggaaatgct
    13081 ggaagactaa acatatcgtc tagctgataa gcaagctcat catgaacgga agaataaccg
    13141 caatcttcaa tgattgcttt cacattatct ggtagttttt ctccgctagt catcataact
    13201 gttgctgctc ccatgctgac accgtataga acgatttctt gcgattttcc attgttttct
    13261 agcactttgt ttatccactg tacatagtct ttacgctctg gccatccaaa tccaatgtaa
    13321 tccccttcgc tttttccatg tcctcttgca tcaggaacaa ggacattgta acccatatca
    13381 tgaaacatct ttgcgtaatt ggtcatcgtt tcagcgtttc ccatatagcc atgagccaca
    13441 agagctgttt tttcactttt cgtttcagca ggaagataaa tcgctgataa tttcagaccg
    13501 tcttttgaag tgatggtcca atcgcttcgg ttttcttttg aactaaacca tttatgtgca
    13561 tccgtttctt tggatgtctg tgttgtacca ggtgtatctt cgtctaaaaa gtctttctca
    13621 gaaggcacaa cagcataatt ataaaaataa ttccctgcaa acactaacgc aacaatcaga
    13681 gctaaagcga cgcctaaaag gattttcatc caaagtttca taaatcatcc atctcatttc
    13741 tcttttttca tataaccttg aattagtata atcaaagaat ctctactatg caatgttcat
    13801 ttttataacc cgcgaattgt aaaattaagt tagaaaaata aaaaggcatt tatggtacac
    13861 tcaaattgta tttccgacga aagaaaacaa aggagtgtaa ccataaatga cctacaaaca
    13921 tcttaccata gacgaactga caatgataga atcatattat cttcaacata ataagccggt
    13981 tgaaatcgct aaccgaatgg gacgtgctat acaaactatt tataatgtag tcaataagtt
    14041 caagcaaggc aagactgctc ttgattattg gcaccagtat aaagaaaata agaaaaaatg
    14101 tgttagaaaa gtcattcaat tacctgctca tgaagtagat tacattaaag agaaagtcac
    14161 tcttggttgg acgcctgacg tcattatcgg gcgaaaagaa aggtctgttt catgcggtat
    14221 gagaacactt tatcgtttat tttctaaagg aatatttgat attgacacac taccgatgaa
    14281 aggtaaaaga aaacccaatg gccatcagga aaaacgggga aaacaacagt atcagcgctc
    14341 aatccatgat cgacctgata attatcctga tttcaattct gagtttggtc accttgaagg
    14401 tgatacgatc gttggcattc atcataaaag tgccgtcatt actttagttg aaagattatc
    14461 taaagtcatt atcacgatta aacccaacgg ccgtaaggca ttagatattg aaactgccct
    14521 taatcaatgg ttttctcgct tccctaaaaa cttctttaaa tctattacgt ttgactgtgg
    14581 aaaagaattt tctaactgga aagccattag taaccaacat gatattgata tatattttgc
    14641 ggaccctgga acaccttctc aacgcccatt aaacgagaat tctaacggga ttctgcgtcg
    14701 taatggactg ccgaaatcaa tggattttag aaaagtgaat cagacattta tttccagtgt
    14761 cagcaatcaa cgtaatcata ttccaagaaa atcattgaat tacagaacac caatcgaaat
    14821 atttttgagc tatgtacaag aagcatttta ttctagctta atttgacaaa tcataaccta
    14881 taaaaaaaca aaataaaaaa gcagaaataa ctggctattt ctagcggatt atttctgcaa
    14941 taactaatta tctatttttt attttcaatt aatttaaagc ttgaccatgg tttcaaaaag
    15001 tcaaggagga ataattcgtc atcggagatt cttcctacaa cattgacacg tccgtcgttt
    15061 ttcatatcct tcaaggcgat ttgtgtttct cctttgtatt gaccgtaccc ttcattgtca
    15121 atcagtacat ccccatgatg catatctcgc gtattatgag gcgggaaatc tttatctttg
    15181 tagtatacac gagtcatcgt tgaacgaagg atatattctg agcgatcccc tcgataacta
    15241 tgaaggttat caaacaagca gattcgttcg ttttctgtaa taccttcttc cgtatctact
    15301 ttcaatgttg gataatccgc gttaaatgct tctgccattt ctttcaattc ttcttcactt
    15361 gcgtacgcat ttccaataga aatatcatca atcaatcctg taaggattaa atgcttcact
    15421 tgtgtcgcaa tttcaagatc tcggtggtct tccagcgtgc acaagccatc ttgcgtaggc
    15481 caagggccaa actcagcaga ttgcgaattg acgaatgcca tcgtattcaa attatatttt
    15541 ctgaattttt ctgaacaaaa aacaaagtgt tcgtatccta aaccagagta tcgatgagga
    15601 taaaaattat gagaacctaa taaattatcc gtgtttggcg aataactcat gatgttgtca
    15661 acgtaattcg tgcccgaact catattgatc tcgattttga taccaaaagg attgcgcgtc
    15721 atttttgctt cttctgctcc tgtgaatccg atatctaagc ggaccccgta ggcacccatc
    15781 ttatggaaaa aagataagtc atcgtaagaa atctccaact gttcaaataa cgctggattg
    15841 atatcaacca ttacttccat gcctaggcta ttcgcgtaat caactacttc tttaaattct
    15901 gaaagaactt tttctttatc atcattgatc tgcagcaaac tggtaaaaac ccgtttatac
    15961 ccatacttat gagctaaatc caagtacgct ttgtcctttt caaatgttga ccgttctgga
    16021 taaatcgaga ttcctaattt tcccatatta ccatttcctc ctgcatcttt tcgtttttgt
    16081 atccacttac attatagcaa acacaaagta aatggtctac accttttctt tttcttttaa
    16141 aataaatgat aaattccaat aatttaagta ggtattttcc ctctattttg ttatcattaa
    16201 agataacaaa atagtaaatt ggaaaggaac agttatgaag aaaaataaag ttattttaag
    16261 tattagttta gcagcagcat tgctgtttgc tgctggttgt tctgcaaaca acacgacttc
    16321 ttctagttcg tctacagaaa gttcaaaaag tacatctact gcggaaagca cgactgccag
    16381 tagcgtcgat ttgaacgcat tggaattacc acaattgacg aaagatgtcg ccgaaaatga
    16441 agatctggtc gaaatggtga cgaataaagg cacaatcaaa atcaaattat ttcccgaaca
    16501 cgcaccaaaa gcggttgaaa actttatgac acatgcaaaa gacggttact acaacggact
    16561 gactttccat cgcgtcatca aagatttcat gatccaaggt ggcgatccta aaggcgatgg
    16621 cactggaggg gaaagcattt ggggagaagg atttgaaaca gagatcaaca accaccttta
    16681 taatataaga ggtgcgttat ctatggctcg ctcacaagat cctaacagta acggcagcca
    16741 gttctttatc gttcaaaata cagatgatat gcatgatggt cttttaaaag acgactatcc
    16801 tcaagcaatc atcgacgctt ataaaaacgg cggttatcct tcactagatg gccattatac
    16861 tgtcttcggc caagtgattg aaggaatgga tgtcgtggat gctattgcaa atatcgaaac
    16921 agatagttca gacaaaccaa aagaagaagt aaaaatcgat aaaatcaata tactgcaaga
    16981 agcaaaacaa aaataaaaaa ataacgtctg aatcctgcat agatgacaac gtatgctagg
    17041 attcaggcgt cttcttttta cataaaaagc aagtaagctt ccttttgttt tgctatatca
    17101 ggttttatag tcaagcattt tggttgacga tgaacgtgaa ctcgcactca cagacttttt
    17161 tatcatctac atatgctgca gataacgctg taccgactga tcccttcatt ttggtgattt
    17221 caaaatgaca tttcagcaca tctcctggaa caactttttg acggaatttg gccttattga
    17281 tcccaccgat ataagctctt tttcctagaa actcttctga ttttaggata agtatcgaac
    17341 ctgcttgtgc cagtgtttct agaatcaacg cacccggcat cactggattg tcaggaaagt
    17401 gaccttggaa aaaatcttca ttgattgtta cattttttgt cgcaacgatc ttttttcctg
    17461 gttctaaagt atctacataa tcaatataac aaataggata acgattagga atcaattcca
    17521 ttacttcagt agcagataat acgtaagaca taattaaact ccttctttca ggcaattgcc
    17581 attttcatta ctttgactat caaagtatca tattcctaaa tatttagcaa tcttttttta
    17641 atttaagaaa aaatagtttg acaatcaaaa cattttgact aataattaag aaatcaagaa
    17701 gttattttag ctattattct ctattttttt acgactatca aatttttatc agaaacaaag
    17761 gagagtcatt atgtcatttc tagaaggaaa aaaaatcgtc attatgggcg tcgctaacaa
    17821 aaaaagcatt gcttggggtt gtgctgaagc aatgttgaaa caaggggcag aaattatcta
    17881 tacttaccaa aatgaacgaa tgaaaaaatc attagtcaaa ttggtcggcg aagaagcatt
    17941 cactgtagaa tgtgatgttt ctagcgacga aagcatcgaa aaagcaatga atgccatcgg
    18001 tgaatatgct ggggagatcc acggccttgt ccatgcagtt gcttacgcca acaaagaaga
    18061 attgtccgga aatgtgtctg atatttccag agacggctat caattagctc aagatatcag
    18121 cagctactct ttaattgctg tatcaaaata cgcacaaccg tttcttgcac caaacagcgg
    18181 gatcgttagc atgacttatc taggttcaga acgcgcaatc ccgaattata acatgatggg
    18241 tattgcgaaa gcttctcttg aagctgctat ccgttatttg gcagctgagt tctcgcctaa
    18301 aggaattcgg gtcaatggaa tctcagctgg ggcaatcaaa acattagctg tcacaggtgt
    18361 taaagactat caaaaactga tccagttatc tgaatctcgt acgcctgatc agcaaggtgt
    18421 gacgatcgaa gaagtcggta atgcttgtgc tttcttaatc agcccacttt ccagcggaat
    18481 catcggtgat attatctacg ttgacaaagg tgtccatctt tcataaactt ttgttgcatt
    18541 ctttaaagta aaacatataa aaatcaggaa aaaacttttt aaagtctctt cctgattttt
    18601 tctttttacg tttttttcaa ctcattactt tgaaattatt ccacgacttc aatccagcct
    18661 tctggtgctt ctatgtctcc aaattgaata cctgtcaatt catcatacaa ccgttttgtt
    18721 actggtccta cttccgtttc actataaaat acatgaagat tgttattgtg ataaatccca
    18781 ccgattggag aaataacagc cgctgtacca catgcaccag cttctgcaaa ttgatctaga
    18841 tcatcaatga aaatatctcc ttcaattgct tgcagtccta gtcgttcttc agctaactgc
    18901 aacaaggaat atttcgtgat acttggtaag atagagggcg attgcggagt gatgaatttt
    18961 ccgtcttttg taattccaaa gaaatttgct gcacctactt cttcgatttt cgtatgtgtg
    19021 gctggatcaa gataaacaca atctgagtaa tccagttctt ttgcttctgt tcctggaagt
    19081 aaactcgctg cgtaatttcc gccgactttt gctgcaccag tccccttagg agcagcacga
    19141 tcgtaatcag atacaataaa attcgttggt tttagtccac ctttgaaata cgctcctact
    19201 ggcgtacaga agacgacaaa taaatattct ggagctggat ggacaccaat gttttcaccg
    19261 accccaatca gtaaagggcg caagtataat gtagcgcctg ttccataggg cggcacaaaa
    19321 tcttcatttg cttttaccac ttgcttgaca gcatcaacga acatcttttc agggaccatt
    19381 ggcatcagca atcgtctagc actttgattc atccgtcgac tattttgttc aggtcgaaag
    19441 agattgacct tgccgtcttt tcgacgataa gcttttagac cttcaaaaca ttgctgacca
    19501 taatgaagcg ctggagagcc ttcatgaatc gtcaggtaat tatcttctgt caattctcct
    19561 tcttcccatt gtccgtcttt ccatttggca ataaaacgcc aaggagtttt gatataagaa
    19621 aaacctagat tgttccaatc gatttgcata tacttaccac cttcgttatt ttctccacat
    19681 tttatcatta tccatattat ttgtcatttt attttcagct tttttccttc attatagtta
    19741 tttttgctat ttcctttttt gaaaacttct tggtacaata cagaaagaat caaattttag
    19801 aaaagaggat tttatgtttt cattattagc aactgccggt acgacagact cttctggcga
    19861 gacattgaca gatcaagctg tcagcaaagt aaatgcgttt cagcggtttt gggacgggat
    19921 tgattgggac gccattttgg ctgcctttat ccaaaaaagt ttatatctga tttttttgat
    19981 cgtccttttt tggattcttc accgtgtggg aaaatatctg attgataagt cttttaatca
    20041 gtattctaaa aaagccattc taaacgagag ccgcttaaag actttacata gtcttttaaa
    20101 tactattttt cattataccc ttggtttctt ttttatctat gcaattttat ctgctatcgg
    20161 tgtgccgatc ggatcacttt tggctggtgc cggaattgca ggtgtggcaa tcggtcttgg
    20221 tgcccaaggg ttcatgagtg atgttattac cggatttttt attatcatgg aacaacagat
    20281 ggatgttggg gactacatca agctagcaaa cttaacgatt gaaggaaccg tcgtatctgt
    20341 tggtatccgt acccttcagc tgaaagcaac ggatggtact gtccatttca tcccgaatcg
    20401 aaacatcacc acgatcagca atctctctcg tgcaaatatg caagtacttt tagatattcg
    20461 gattgttcct gaagaaggat atgacaaaat ctatgagatc attgatcgag taaatcgtac
    20521 attagctgaa aaataccaag aagagctcca aactgaacct tctatctttg gattagtgga
    20581 tcttggaaac agcaattttg cgattcgtac ggtctgctac gcattgaacg gaaaacaata
    20641 tgccttaaaa gaagagttct tgagctccta tgtcaaagaa ttgacagctt ctggtttcac
    20701 gattccgaac agtccaattg ctgtcggaaa ataatttgga caaacgatgc aacgaatctc
    20761 actaaaaaga gcgtgggaca aaagtaaaga acacttttgt cccacgctct aaacacgtat
    20821 aaacggcgga agcagaagca actccttcgg aaataagctg aaattcacaa aaatttgaaa
    20881 agcaattttc gtgaattcct tcttatttct tggagttaaa cgcttttgtc ccagcctctt
    20941 tttcaagata aagtcaaaac tggtacgctg ttttttctac ttattttttg attatctttt
    21001 agtttctcgt tctttagctc acgatatcga tttgttcttt taattcttcg attttcggag
    21061 acaatatatt acgacgttct aattcatgca ccatgaagtt tacggcttta agcagctctt
    21121 ttcttgtaat gattcctttg aaaatccgat cttctgtgac aaccggtaaa aaaggcgaat
    21181 cgactaacaa atggagtact tcttctagtt cccaattttc atcaattgtc ggaacatctg
    21241 tttctgtcac atcagcaacc gttagtcctt ctaacgggtc catgctgatt gtttgcaagt
    21301 caatcatttt attgaccaca tctgataaac ttactagtcc tacaaagtga tcatcttttc
    21361 ctaatacagg aattttggaa taaccgacct tcgataacac aagtaaacca tgggacaatg
    21421 gatgatgata cataacattt gccacatttt ctgcaggaat caaaaacgtt tcctgatttt
    21481 ccagcagcat ttctcttact ataggtccaa tcatctgatg gcctccattt ctatttcatt
    21541 caacactact attttaccga aaccggatgc aaaattcata aaataaagct tatttttatt
    21601 aaaaattaga gtttttttat tcagcgctct ctcgaaaaag aaaaggccaa ctcttcaact
    21661 gcctgatggg cacggttata gtattgaaca gaaatttggt catctaaact ttcgataaga
    21721 gcatatgatg ggatttggat cgggcctcta ggctgagaaa tgctaccagg attcaaaaac
    21781 aggattttct gatccatctc acagcctatt tgatgggtat gaccaaaaaa caccatatcg
    21841 gcagttgcag ctcgagcttc gattgctaac tgtgtcaaac caaatcggac attcgataaa
    21901 tgaccgtgag tcatgaatac tgtatcctga ccagtttgga tcactttttt ctgttcgaat
    21961 cctggtccat aatcacaatt accttgaacc acttggaatg tatcccataa tgggtcagaa
    22021 gcttctaatt ccgaatcacc acaatggaaa aagatatcca cttcagaacg ataacgatct
    22081 actaagtcaa cgaggatatc tctgtctcca tgattatcac ttactactaa ataccgcatc
    22141 tatctctctc cttccagcca ttgtttccac tcggcactca attttttcat tgcttgagcc
    22201 cgatgactga tcttgttttt ttcttcgctc gataattctg ctgctgtttg tttcttacct
    22261 tctgggataa ataaaggatc atacccaaag ccattttcgc cagatggtat acgggctact
    22321 cgaccgggcc attccgcttc tactacaagg ctgtcttttt tgggtgccgc gaatactaac
    22381 gtacaatgga attgtgctgt tcttttttca tccggcacat ctgtcaattc atataataat
    22441 ttggcgttat tccccgcatc acttttttgt tcccctgcaa aacgtgcaga atagattcct
    22501 ggcataccgc ctaaagcatc cactttcaaa cctgaatcat ctgctaagac tggctgatca
    22561 agcaattgtg caatcgtttc tgcttttaat cgggcatttt cttcaaatgt gctgccagtt
    22621 tcttccacat ctggcaattc aggatagtca agtaatgttt ttacatgata tcccgcttct
    22681 ttgaacatat ttcgaaactc ttctgctttt cctggatttc ttgtcgcaat gatgattgtt
    22741 tttgtttctt ctatccgctc atcattttga gcaaactctg ttagcaaagc atgtttttgc
    22801 tctttgatca aatcttcaat cgcgtttttt ccaaaaaaga gcatttcatt caactgttca
    22861 ccatcaaacg ttgcttcttc tccagttcct tgaatctcca cgaattttcc agattctgtc
    22921 attacaagat tcatgtctac aagtgctgcg gaatcttctt ggtaatccaa atctgtgacg
    22981 caagtcccat ctggtaagat tcctacgcta actgcagcaa gatgttcttt tattggatct
    23041 tctgacaatt ctttttctct taaaagtttt tcaatggcta atttcaatgc cacaaatgcc
    23101 ccagtgatac ttgctgttct agtaccgcca tccgcttgga tcacatcgca gtctacgatg
    23161 atactacgtt ctcctaattt ttccaagtct actactgcac gcaaggaacg accaataaga
    23221 cgctggattt ccattgttct accagaaagt ttccctttgc tgctttctct acgatttctc
    23281 gtactcgttg ctcgaggcag catactatat tctgctgtca cccatcctgt tcctgtttct
    23341 ctcaaaaaag ggggaacaga attttctatt gttgcagaac aaataactgt tgtatcacca
    23401 aaacggatca ctaccgatcc ttctggatat ttgaaaacat ttgtttgaag ctccagtttg
    23461 cgaagctctt gggcttttct cccgtcatga cgcatcctta ttttcctccc aattcgatat
    23521 gttctacatt taagtgtccg attccaagcc agtcttcagc tatttcctcg aaaagtttgg
    23581 cagagccagt tgtataaaac tggcataatg tccgaccatt ttgcggtgaa ttgctcaaat
    23641 tgaaataatc taacagcata gatacttcac ctactgtttc tgctccagaa tcgatcagtt
    23701 gaacattttc tcccattaca ttttgaatga tggggcgtaa taatggataa tgggtgcatc
    23761 ccaaaatcaa tgtatcgatt tttttagtgg ttaaaggagc taatgtttct gccacaattt
    23821 ttttcgccac cgatgaatgg tattcattac tttcgacaac tgaaacaaat ttgggacaag
    23881 caagacttgt cacagtcaat tctggtactt tctctttcag tgctttttca taagcttgac
    23941 tttttaccgt accaatcgta ccgataatgc caacttgttt attttgtgtt ttttttactg
    24001 ccgctctagt accgggaagg atcacaccga tgactggaat agaaagagca gctttgattt
    24061 cttctaaagc caccgcagtt gcggtattgc aggcgatcac cagcatcttg attccttgct
    24121 ccaccagata atccgtcatt tcccaagtat actggattac ctgttccgcg ggtctagggc
    24181 catatgggca gcgtgctgtg tctcctacaa ataaaatatt ttcattcggt aattgtttca
    24241 gggcttcttt tactacagtc aagccgccga cacctgaatc aataaatccg atagggcgat
    24301 tatctgtcaa tcgtatcatc ctttttttca ataaattcta tcctccctat tgtgtacttt
    24361 ttagcgtgaa ttttcaagtg ctcttacttg cttaaaacaa tcgaaatctc tttttttcga
    24421 atggaaagag gaaaagcggt tgtgacttta gtttgccaca accgctaaaa gaatcatcta
    24481 ttaataactg taccgtctct tttccaagta accggaaagc agagaaagcg cgtaacatac
    24541 cacgaagtac ataagtgtca tgatgatgaa catcggaagc acataattgg tgttctgtcc
    24601 ataaataata cgtgcctgat gagaaagttc aggtaaagaa atgattactg ctaatgaagt
    24661 atctttgatc agtgaaatca attggctcac aattgccggg atcattgatt taaatgcttg
    24721 cggtaacacg atcgttcgca tcgattctac ataagtcagt cccgttgata atcctgcttc
    24781 catctgtcct tttggaacag cattgagtcc agctcggaaa atttccgaca acatagctga
    24841 ctcaaaaatc gttaatgctg cgacagcgga ccagaagatg ttcatctgaa tgccgatttg
    24901 aggtaaggca aagtaagtga agaaaatgat caataataat ggaagattcc gtataatatc
    24961 aatcactaca ccaaggattt tggaaaagaa agggatattc gcaaaacgaa tcacacctgt
    25021 cagaccaccg atcaagaaac taaaaatgat cgaaaacaat gaaacttcaa cagtaacctt
    25081 taatccttcc aataaaaaac ggatattcat ccatgaaaaa gcgccgctaa aatccatgta
    25141 tttcccctcc ttctatgaac gaaccgccca ttttttctca agataaacca ttaagtaaga
    25201 taacggtagc gtgataacta agtaaaataa cccaacgatg atatacgtat cgaaggtatt
    25261 gaatgtttca ctagcgatca agtctccttg atacatcaaa tctaaaccag ctacgattgc
    25321 taaaatagat gagtttttta cgaggttgat aaattggttg cctaatggcg ggataacgat
    25381 tttgaatgct tgcggtaaaa caatataacg catgatttct gaataggtaa aaccagaaga
    25441 tagtcctgct tctgtttgac cttttggtac ggtttgaatc cctgaacgta ctgtttcagc
    25501 aataaaagca gatgtataga tcgttaatcc aatcgtacct gcttggaatc catctagatt
    25561 aaaccaataa atcggtacga caacataaaa aaacatcacg atgattaata atggaatgtt
    25621 tctaaaaaat tctacatatg cctttgctaa ggcgctcact actttattct ttgataattg
    25681 gaagattgcc attaacgttc cgataatcaa actaaacaca agtgctaaga cactcgaaaa
    25741 caatgtgatc ttgaacccgt cgacaaagat tggtccataa gtttgtatca attcgctcat
    25801 tgcctctccc ccttactcta cttttccttc agtttcattt ggaaaccatt tttgatagat
    25861 tttatcgtat gtgccatctg catgcatttc ctctagcgct tggttaacag ctttcaagaa
    25921 gttttcttgc cctttgttga tcgcaatccc gtaaggctca ttagtaaacg ttccaccaac
    25981 taactcatac tctggatttt catctgcaat ccctaacaaa atcgcattat ccgtagtcat
    26041 cgcgtctccc tgaccagatt gtaaagcagt aaatgcttct gcatagtttt ctaattctaa
    26101 aatttttgca tctggtgcat gctgtcggat attcgcagcc gatgtagaac ctttgactgc
    26161 tagaaccgtt gtagaagcat tcaaatcatc tacacttttg atttggcttc ctttctttac
    26221 caacaaagct tggccagcat cgaaatagac atctgaaaag tcaacctgtt tttttcgttc
    26281 atctgtgatc gtcatcgttg caataattgc atcgatattt ccgtttttca ataatggaat
    26341 ccgagtttta gaagtgactt caacaaattc tgtttttcca ttgtcaccaa ggatcttttt
    26401 agtgattgct tttgcaatat ctacatcaaa tccttgtaca gttctgctct caatatccat
    26461 cattccaaat aatcgagtat catacttgac accccagatg atttcattgg tagatttgct
    26521 tcgctctaaa atatcttcat ttgccaaccc atttccttta catccggcta gtgcaagaaa
    26581 agcaatgcct aaaaggaaaa tcaggcgtat tttttttaac ctgcgcatct ttttcctcct
    26641 atcaatgatt gataacttta ctgataaatt gctgtgctcg gacttcattt ggattttcga
    26701 aaaagtctct cacatttctg ctgtcttcca atacttctcc atcagccatg aagataacac
    26761 gatccgccac ttctttggca aagcccattt catgtgtcac gacaatcatt gacataccgt
    26821 catgagccaa ttttttcata acgtctaata catcaccaat catttccgga tccaaagcag
    26881 aagtaggttc atcaaacagc agcatctcag gattcatcgc taaacctctg gcgattgcca
    26941 cccgttgctg ttgtcccccg gataacatgg aaggataaga atctttctta tctaacatat
    27001 tgacagtttt caaaaatttc tccgcgtttt tgactgcagt tgcctggtct tgcttcaaca
    27061 ctttgattgg tgctaatttg atgttttcca gaacagtttt atttgggtac aaattgaaat
    27121 gttggaaaac catgccgatg ttttttcgga cttctgtcag ttttgtcttt ttatcatgca
    27181 agtcagtatc attaatcagc agcttacctg aagagatcgt ctctaatcca ttgatacagc
    27241 gaagcatcgt gctctttcct gaaccagaag gaccaatgac aacgacaact tctcctttct
    27301 cgaattcgag attgatattt tttaatgcgt ggaacttgcc ataatattta tccacgtgat
    27361 caaatttaat cattgccata gaattacact cccattatta tttagtaaga tttcttttaa
    27421 agatgtataa taaaatacat tatatctgat agtttagtaa tttgtaaagt ttcttagaac
    27481 gtttattctc ccataaatat ttcttccatt tctaatctat tagttatttt atcctctttc
    27541 cttgtttttt ccttaggaac tgttgtttct tttcaggaaa aacggtaaga tattaagtgc
    27601 tcagacttac aaatcgtaaa gaggtgtctt ttttgaaaaa tattatttta acgggagatc
    27661 gaccaactgg gaagctgcat ttagggcatt acgtcggttc tctaaaaacc cgagtggcta
    27721 tgcaggcaga tgaagacaac caactgtttg tcatgattgc tgacatgcaa gcactgacag
    27781 ataatgctaa aaatcctgag aaggtttcat caaatgtctt gcaagttgct ttagactatt
    27841 tagccgtggg attagatcct gcaaaatcta ctttatttat ccaatcacaa attccggaat
    27901 tagctgaatt aaccatgtat tatttgaact tagtcagcgt aggacgcgtt cggcgcaatc
    27961 cgactgtcaa aacagaaatc gaacaaaaaa aattcggtga aagcgtgcct acaggattct
    28021 ttatctatcc tgtttctcaa gcagcagata tcactgcatt caaagcgaat cttgtacctg
    28081 ttggtgagga tcaaaaacca atgctagagc agacacagga aatcgtacaa agcttcaatc
    28141 atacatatgg tgaagtcttg gtggaaccaa aaggcgtatt cccaccaaaa ggaatgggta
    28201 gattacctgg aatcgatgga aatggcaaaa tgagtaaatc gttaggaaac ggtatttata
    28261 tctccgatcc tgccgatgtc ttacagaaaa aagtcatgag tatgtatact gatccaaacc
    28321 acatccatgt acaagatcct ggacaagtag aagggaatat ggtcttcacc tacttggatg
    28381 tattcggaac agataaagaa gcaattgaag aaatgaaagc tcattaccgc cgcggcggac
    28441 ttggtgatgt aaagatcaaa cgatacctca ttgatgtatt ggaagctgaa tttgcaccga
    28501 tccgtgcgcg ccgagaagaa ttggaaaaag atccttcagc tgttatggaa atcttacgta
    28561 aaggtagtga agaagctgct aaagtagctg cacaaacact ttctgaagta aaatcagcaa
    28621 tgggaatcaa ttacttccat taattcattt actctaaaaa agcaggctgt aaaggcctgt
    28681 ttttttatct cgtctctgtg ctattccttt tttaaaatca aaaaaagaga tgtgacgaag
    28741 ttgtgtcaca tctttttttc aaatgtatgg tcttcaaaag ctacttgatc gttacttact
    28801 atattttcct tcttagcgaa tacttgcctc taggttttct accaacgctt tttcgacttt
    28861 ttccattgct ttattgattt cttcatctgt caatgttgct tctgggttga cgaatgtcag
    28921 gctatacgcc atggatttat gtcctttttc aatgttttct ccttgataga catcaaataa
    28981 ttggatatct gttaaaaatc ttccggcagc agaacggata acttctgtta attcctgatt
    29041 tgtcacagtt tcttttacaa gcaaagcgat gtcccggctg actgctggga attttgtcac
    29101 tgcttcgaaa acgatccctt tttgagcagc ttccactata gcagataaat caaactcagc
    29161 aacatatgtt tctggaatat cataactttt tgtaatcgtt ggatgcactt gaccgacaaa
    29221 accaataaat ttttcgccaa ggtaaatcgc agcagttctt ccaggatgca tttccttcat
    29281 ttctgtcact gtttgataat ggacatcttc agtgatgcct agttgttcaa ataagttttc
    29341 taaaagaccc ttgatggtga aaaagtctac attttgagct ttcgtctgcc aatctttttc
    29401 ttcccaaata ccagaaatag cgattgctgc atgttttact tcttgcggca gatgtgtacg
    29461 tggatcattt tcttggaaga acacccgacc aatttcatat aaagcaatct ctgtattttt
    29521 tcgggcagtg ttataactga tatcatctaa tagtccgctg atcaaattca ttcgtaatac
    29581 agaacgttct tcgctcattg gccagtccaa acgtgtaata ttactttcat ttataacaaa
    29641 ctgtcttgat ttttcttctg ttgtcaatgc ataactgatt gcttcgctca atccgcttcc
    29701 ttcaaagatt gtacgaattt tacgagtagt ttcttgttct tttgacaagc ttccagcaac
    29761 cgtttctcca cttggaagtg tagatggcaa ctggtcgtat ccataaatac gagcaacttc
    29821 ttcgataata tctgcttcga tttggatatc ccagcgtctt ggtggtacta ctacggaata
    29881 aacatactcc ttttcttcat agctaaatcc aagtgcttca aaaatctcat ttacttcttt
    29941 aacgacaaga gatgttccta aatattgatt gatgcgttca agtgaaatct tcactgatac
    30001 gtcttctgct ttgatctctg agcctttgac cgcgccttgt agaacttccc cacccgcaag
    30061 agaaacgatc attgctgcag caacctcact ggcttctcca acagtcgcat ggttgattcc
    30121 tttttcaaaa cgtgcagagg attcactacg caaattaaat tgttttgctg tacgacgaat
    30181 cgaaattgga tcaaataaag cagattctag tgcaactgtt gttgtttcat tcgtgatctc
    30241 tgagtctaac cctcccatga caccagctaa agcaactggt tctttgccgt tagtaatgac
    30301 gagattgtca gttgtcaatt cccgagattc tccatctagt gttactaatg tttcattttc
    30361 ttttgcacgg cggacaaaga tctcttttga tttcaatttg tcgtagtcaa atgcatgtag
    30421 tggttgtccg aataaaagca aaatatagtt cgtcacatct actacattgt tgattggacg
    30481 aatgccttcg ttcatcaaaa gattttgcag ccattgagga cttggctgga ttcttactcc
    30541 ttcaatgatt ctgatttgat aagcaggaac tgcttcttta tcttcaactt ccacttgaat
    30601 tttatcgcta gcaggacgtg aggattctac cagcttttcg tcatcgaatg taggagtctg
    30661 acgataaatt gccccaactt cataagctac gccacgcatt gacaatgcat ccgcacgatt
    30721 cggtgtgata gataattcaa taatcgaatc atccatatcc aaataaggaa aaactggatc
    30781 gccatttaca gcttcttgtg gcatataata gataccttca gcgtattctt tcggtataac
    30841 actatctgaa tagccaattt cttgtaatga gcaaatcatg ccatttgata cttggccacg
    30901 catttttcct tttttgattt ttacattacc agcgatacgt gagttaggaa gtgcaacaat
    30961 cactttgatt ccaaccttca cattaggcgc tccacaaacg atttgagaca gttcgtcttc
    31021 gccaatatcg acttgacaaa tagaaaggtg atcagaatct ggatgtggta cgcattcctt
    31081 gacttcaccg acaacgattt ttttcaagcc ttcttctgga accgttactc cctctacttc
    31141 gattcctgtc acagacatct tatccgctaa ttcttttggt gttacattcg ataaatctac
    31201 ataacgattg agccatttat atgaaactaa cattttctta ctcccccttg aactgactta
    31261 agaaacgtaa gtcattttga tagaaattac ggatatcatt cactccatac cgcaacatag
    31321 ctacgcggtc tggtccaagg ccgaaagcaa agcctgaata ttcttctgga tcgattcctg
    31381 acatcttcaa cacattcggg tgtaccatgc cagctcctaa aatttcgatc catccagtgt
    31441 atttacatac gttacaaccg gcaccaccac atttgaaaca gctgacatct acttctactg
    31501 atggttccgt aaatgggaaa taacttggac gcaaacgaat ttcacgatct tccccaaaca
    31561 tttttttcat tacgacttct aatgttcctt taaggtcgcc cattgtgatg tttttatcaa
    31621 caactagccc ttcaatttga tggaactgat gactgtgggt cgcatcatct gtatctctgc
    31681 ggaagacttt ccctggcgag atcattcgta gagcaccctt agagaaatca tgtttttcca
    31741 ttgtccgtgc ttggactggt gaagtatgtg tccgaatcaa tatctcgtct gaaatataga
    31801 aagtatcttg catgtccctt gctggatgat cttttggcag attcatccgt tcgaaattgt
    31861 aatgatcaga ttctacttca tatccttcta cgatctgata gcccataccc acaaaaatat
    31921 cttcaatttc ttccatgatt tgtgtcacga tatgacgtgt accatgtttt acttttctac
    31981 caggtagtgt cacgtctatt gtttcttttg ccaaagctgc atttaacgct tcttcttcta
    32041 atacttgttt ttttcgctcg atctcttctg tcaaaagatc tcggatctca tttgcgaaac
    32101 ttccgacttt tggtcgctct tctggactta gatctttcat cccacgtaat acttctgtga
    32161 tcggtccttt ttttcctaac gtttcaacac gtatttgatt taattcattt aaatcttgtg
    32221 ccgctgtgat tttgacgagc gttgcttctt tcaagctctc taattgtgct tgtagagaca
    32281 tgtgcttgtt cctcctttaa attccaaata caaaacaaaa agacctcatt cctgttaagg
    32341 aacgaggtct tcgcgttacc atcctaattt gcggataaat gacttacacc gcactcttac
    32401 ttcgttaacg acaattgccg gtctgatttt atcagacgaa ctcggaaagt gaacttcatt
    32461 tttcaaacac aggatctgct ttcagtctgc gacagatctc cctgaactgg tttagccaaa
    32521 ctactctttt tcgtcatcgt tctttactta ttcgtatgga ctatagttta caagattttt
    32581 tttacaaaat caaccgcatt cttcctctgt gatccatttt tcgctccaaa cttgtatttg
    32641 acgcatcgct ttttgcaagt ctgctccttt ttcagtcaag agatattctg aacggctctt
    32701 ttcgctacag gcaaagtttc gagtgactat tccttctttt tctaattcct tcaagcgttc
    32761 gactaatact cgatcactga ccatcgggat ttttgccgca agctcaacaa agcgttgcgg
    32821 accgttttcg agtagtacat cgataatcaa tccgttccat ttttttccta aaatagagaa
    32881 tgttttttca aatttagggc ataaaacgaa ttctgtctgt gttagctcca tcatactcac
    32941 ctcttcccag agtatagcat aatccttaca aaacataagt caagtttgct caattataat
    33001 tatttgttaa tgtttataat ttgtttcact cgaagcaaaa ttaggaaaac attttctact
    33061 ggcttattca aagcttctga cattgcttgt tggtaaagtc ttagctgtcc ttgatatttt
    33121 tggacgattg catctatttc tgctggatca tccggatgta aaataaaatc tgttttaaaa
    33181 tcatagatat tgagatgatc tttttcttct aggtatccat cgacgattcc gtggattaat
    33241 agttcatctt cttgatttgg atagtcttga aatacttcgt cagcaggaag cagcatggaa
    33301 aaaggttgtt ctcgttttac gttttctttg ttggcaatca gctgttgacc aagttctgtt
    33361 tgaaagaacc atataataga agaaacatct acttttttcg cgactttttc gtctactaac
    33421 cgtttcctta ccaattcctg taatttttga tggatactct ctgtagttgg catctctaat
    33481 ggcagtaatt gtaacaaagc atgcgtagca gttccaacag cagctgctga cacttgccga
    33541 tctttttgca aaaattttgg ttctgctagt tgttcttgcg tataacgaaa ttgacgggat
    33601 gctgctttgt tctgactgct ttccagagtc aaacgtgatt cttgtgtatc atctggatct
    33661 tcgaataatc gtttgatttc agatacagat tgataacttg tggtttgtga agaagcttga
    33721 taaggatatt catatgccag acgtttttgt aacgaatctg ctaataaagt ttcatcttct
    33781 ttcatctgct gatctaagtt aaccagttct ttttcagcaa gcaactgtct ttgttcaatg
    33841 atcgattgct gattcatcca tgaaatagaa aactgtgcat ttgaatgttg aagaaaagaa
    33901 gtcgaaattt cttcctctaa gtatttctgc atttcaggat gacggatcaa tccgtaacca
    33961 atccaattca tcaagctgct tctgcccttc aaacgtagcg caggatcaaa aactaactcc
    34021 tcatgatcag ctgcttcaga ccacgtttgg atcatttgct ctttattttt ataggaaccg
    34081 acaatgaaaa gcttttgttc tgcccgagtc aatcctacat acaatttacg catttcttcc
    34141 gacaacaatt tgttttgctt tgccaatttg atggcttgaa acggtaacgt atcatataac
    34201 actcgtgttt caggatccat atagcgaatt cctgctccaa gtttttcttc aaaagcatac
    34261 cgattgcgca agtcttgtaa gttgaactcc tttgtcatat ctaacaaaaa tacaactggg
    34321 aattccaagc ctttacttgc atggatcgtc ataacgcgaa cagcattatc ttctattgaa
    34381 atgactggtt ctgctaagtc tttatctttt tcttgcattt tttcaatgaa acgcacgaac
    34441 tggtataatc ctctgaaaga actttgctcg taagctttgg cacgatcaac caatgcataa
    34501 agattggctt gtctctgtgc ccctgctggc agaccgacca catactctag atatcccgtc
    34561 tcataataga tatcccataa caagtcagtg atcgaagaac ggcgagcaag ttctcgccaa
    34621 tgctctagtt gcttgccaaa atgttccagc ttagctgcta attcatcttc gtttgatgct
    34681 tgataagcaa gcacagcatc atagtaagta tgtgcacggt tagctaatcg aatgctggct
    34741 aattctggtt caatcagacc cacgatcggt gagcgcaata cagccgcaag cggaatatct
    34801 tgatagggat tatcgattaa ttgtagcagc gagatcatcg tgcgaatttc tgtcgcttga
    34861 aaatagtttt gagcatcatt catctctaat ggaatatcca atgttttgaa aatctctaaa
    34921 atcgttaagt tgttcttctt tgtaggtgtc aagagaacaa tgtctttgta ctctatcgga
    34981 cgactttttt ttgatttttt atcataaatc ataaaggagg aatcaattaa ttgacgaatt
    35041 tttagtcctg tcataaaaag ttcgccttct gttttgtctt ccagtatatc atccgtcgga
    35101 atctcaatct ctgattcttc ctgttctttt tcatagatca tgatttccgg ctcaaactgt
    35161 tcattctctg gaaagtctga aaatccttgg atcagtttgg ctgcttcgtc ataattgatt
    35221 tgacccactg ctggatccat tagttgttca aaaataagat tcgtaaaaga aaggacttct
    35281 tttctagagc ggaagttctc agccaaaacg attcgacgtc cgccttcttt ctttgagaaa
    35341 ttctcgtatt tcccgataaa taaactagga tctgctaaac ggaaagaata gatggattgt
    35401 ttgacatccc caaccatgaa catatttcct tttgtatcat cgggttctct tagccagtat
    35461 aaaatggctt cttgtaattg gttcacgtct tgatattcat ctaccattac ttctttgaat
    35521 ttttttcgat aatgttttga agcttcactt ggcagccata catctttcgt tttttctgtg
    35581 agaatctgca acgctaaatg ttccagatca ttgaaatcca gcacaccttt ttcccgttta
    35641 cgcatactga aaccgtccat gaagctttgc gtgacttttg tcatttcttc gactaacggt
    35701 agtgctttgt ccgttaattc ttccatttgg cttggggaaa caggaaaata acttttactt
    35761 atctgctgaa tcagtttttt tgctttatcc ctcatgccct tgacttcatt ggaaatttct
    35821 ttcaattctg ctttccgact gctcttaaaa gttgaaaaag ttagttgttc caaaccagca
    35881 taagcttctt ctaaccgatc ttgcgagaac gcttcataga tattcttgat ctgctgttgt
    35941 tctccagcta cttgctcatg cattttttct aatccttcac cttgtgctaa ctgagtcatc
    36001 tgttcatata actgtacaca ttggtatata tctgccaaaa ctaaaggacg gatttgtttt
    36061 tgatataatc gagatttcgc tagcccctca ggcaaacgat aattatcgct taactgttct
    36121 agccattttt gggggtcagg gttggcacgg gcaaactcat aaagagaaaa caccagattc
    36181 gtcaagccgt catctgaacg atcattagaa aaattcattg ttaattggaa aaatcgttca
    36241 tcattttctg cataaagtgc ttctctcagc tcgtcccaca catcctcctt catcaagatc
    36301 gtttctgttt catctgttaa catgcgaaag actggatcaa tatcaattaa gtaataataa
    36361 cgtcgaataa ctgtcaggca aaaagcatgt aaggttgaga tattcgctgt gggcaataaa
    36421 actaactgct tagtaaaatg ctgtctacgt acagggtcac tttcgctatt gacggattct
    36481 tgtaatgcct cttgaattct ttctttcatt tctcttgcgg cagcttcagt aaatgtcaca
    36541 atcaataatt catcgatatc aaaacccatt tttagttttt caatcactct tcgaacaagc
    36601 actgtagttt tacctgatcc ggcagacgca gagactaata gattatctcc ttgatcaaaa
    36661 atcgcttgcc actgatcatc tgtgaatcgt tcattttgcg gttttaaagg aatttgattc
    36721 actcttcttc actccttttc aatattctac gcagtgcttc ttccttatct attttctcca
    36781 gacggtggta attattttct ttcagcatca catcaaacgt acagatgctt ctgaatggac
    36841 aaaattcgca ggcaatccgc tgtttatctt tataagctgg atttagtttg atttctccgg
    36901 aagtaatcgc atctccagct aaccgcatat tttcccgatt atgcgccatg aatagttgca
    36961 gttcttcttc cgtgaaaaat ttgtctttac tgaaactacc tttttggtat tcatctttcg
    37021 catttttttt cactggatag atcagtgatt gttcttttgc ttccagtgaa tgatctagta
    37081 cttctaaaag agcgggatca tcgacaaaaa cgccatcata actaaatttt ttcaatgtat
    37141 tcttctctac atcatctgtc tccgtcaata caggattatg aacatgtaaa taatatgatc
    37201 ctgctggttt aacagccgcc tttccagtca aacgtaccgc atccatcaat gctacgtcca
    37261 gatacgtcaa taattgcata gccatgccat aataagcttc tgtgacatcg aatgaacgtc
    37321 cgctagattt gtaatcaacg acgcttagcc aagtatcttc ttgttcagaa gctacatcga
    37381 ttcgatcgat tttccctcga acatggagtt ttccaccatt actcaacggt aattccagac
    37441 ctgtgatacc ttttgctcca gcaatctgac caaatagaat ctctgtctga agaggatgca
    37501 tgcctgtatt tttgctctgt ttttgcaaag cccatgtcac tttttgaatc gtctgtccta
    37561 actggtagcg gatatagttc attcttgcag aactatccaa tatctcaaac cgaagttctc
    37621 cgaatacttc ctgcagcact ttttcagtaa agtctctacg ctgcgcatcg gacatattca
    37681 ctaaggataa ttggtttgaa aacagtagct tgaagaaacg atccaatgat tcatgataaa
    37741 aatcaccagt tgctgctgga gttagaccat aaacagttcg ttctttcaat ttcaaaccaa
    37801 attgcatgaa gtatttgtat tcacaattat aaaaattctc catacgtgaa attgaagtat
    37861 aaatctcttt tccataaagc tcttccgcca ttttttctgg catcgaaaca ggaacattta
    37921 aatgttcctg actttcaaaa atctgtaaag caaaatttcg ccatgacgaa ttcagtacta
    37981 attctttgag cttttgccag tgctttggta caggtttttt ttcatctaaa gctaatcgat
    38041 aaatcctatt gactgtattg attccgcttc tgtaagtccc tacataacaa ttagggtcgc
    38101 tttcgatcgt caaatgctct tttctctcga cgggaacaga taaatattct gtgattctac
    38161 gcaaataagg agacatcttc agcgaaccat ctgtgtcata gctttgtgca taactaagat
    38221 ataatcgatc tgttccggaa agaaaaacaa gataggcttg gaaaggctca aaagagatac
    38281 tttcctttga tgggtcgaat aaaaactgtc catctggcaa ggcctgattt aatacttctc
    38341 gttcttcact ggacaacaat ccttttgtct cttttcggtc tggaaacact tgatcattca
    38401 accctaatgc aaaagtgacg gcagcttgat ttggtcgaac taattccaaa cgattgattc
    38461 gcacttggtc gattgcggta gggattttac cataacttag attttctaga ccacttgtaa
    38521 tgatttcttg gaacagtgac cagtcaaaag ccgattcacc ataaattact acatattcat
    38581 ccaacagatc aatcagcgct ccccatgtct gctcatggtt tcttgccgct tctaagtttc
    38641 ctctgtctac ttcctgatta cgccaaaaca ataattgttg ctgtacgcca ctttggatca
    38701 aaaattgata aaaaacattt gcggcctctt gtcctgtttt gcttttcttt atttttttca
    38761 aaaatactgg tacagctttc tgaaataatc gtctaatcgt atttgactgt tcttccaaat
    38821 actgtacgtc ttcaatctgt tctgcttcaa aatcatacgc cacaaactgc cagtcttttt
    38881 cacgagtcca ataagttcct tgataattgt aagcaagtgc tacattttca gtgatgtcca
    38941 gttttttcct gaattcatct cgctcttgtt tccattcatc aagttcggtt tctgcttccg
    39001 tcgacagaaa taattcagtt ttgaaaaaac gcataatatc acttagccga taagaatagc
    39061 ggtcaagagc gaacagactg ttgatccatt cgatcagcgg atgattttcc atcatttgtt
    39121 cttcatcgat ataaaaagga attgccattt cttgaaagat cggccgaagg atatttccat
    39181 ataaagacat attttttgtc agcacttgga tatcacgata acggtagttt tcttcactga
    39241 ctagtcgtct gatttcaaca gctaattgtc ggacttcttc agttggattt tcagcttccc
    39301 acaaatggag atgctcttgt ccccctattt tgtgtactgc cgctttcttt tggctagatg
    39361 tctcttccca cattgtttgc agcagttgaa gctctgtcgg acgagtctgc tctggtgcaa
    39421 atcggtccac taatataggg actttccgtt ctcttgcact ttgaaaaaga cggaaataaa
    39481 gctttccagt ctcatgaaag agcgtaagta cttctggaag atccgctgta taaggacgat
    39541 ccagcaataa atcgacaacc aattgcccct tttccatcat tgcctgcagt aattgatact
    39601 cttgaccatt gattcgagaa aaaccactga caataaattt gacgttgttg aaatcttgtg
    39661 tctgcatata atttgctagt atagatagtg catcttcatt tgttagtgca cgttgagtca
    39721 attcgctgtc ataagctgaa aaaatcagct tcaagtcttt cattttaagt tgctggtctt
    39781 ctgcattagg tgaatcacca aataaaagca tcaggtcttc tggttgaata tttcctgtac
    39841 gcaattcact gtagagttct tgtaattgac gaataaaccc tcttttattg atttctccgc
    39901 gaaagattgt taattcttcc tcattttttt ctaaaatctg tcgcaagatc attgcagatc
    39961 ctgattctga taattcattt cctgtaagaa gagttgtctg ttgcagcaaa taccaagcca
    40021 gacgataaaa actaaatact tgaacgtttg ttgtgctgaa agtttttttt ccgcttcttc
    40081 ttcgcatctc cgctaaaatt tcttgttcct gttcgaattt gctgtagttg ggaacaagga
    40141 aaaatacttg gttacttgca tcctggtcga gccaagcgga tgcttcgtcg atcaagactt
    40201 gacggtgatc ttttttcccg tttccaagaa taaattgtaa agacatgctt ttcctccttc
    40261 aacacatgat acggtgctcc tttattatat caaaaaatac tgaacatttg ttctatattc
    40321 ttcaaattat atccttttaa ggttctgata tttctacttt tttaagtata cg
//
LOCUS       DAFBVQ010000019        39181 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.019, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000019 DAFBVQ010000000
VERSION     DAFBVQ010000019.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 39181)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 39181)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..39181
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.019"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            212..604
                     /locus_tag="LLC22_001174"
     CDS             212..604
                     /locus_tag="LLC22_001174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5434464.1"
                     /translation="MGEKELRRSMSVFPIGTVMKLTDLSARQIRYYEEQDLVHPERSE
                     GNRRMYSLNDIDMLLEIKDYLSEGLNMAGIKRVYEMAQAKKQEAKNKKPLTDHDVRQI
                     FRDEILAQGGLSKTGHYQSQGLQRQFFD"
     gene            632..1972
                     /gene="glnA"
                     /locus_tag="LLC22_001175"
     CDS             632..1972
                     /gene="glnA"
                     /locus_tag="LLC22_001175"
                     /EC_number="6.3.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332748.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glutamate--ammonia ligase"
                     /protein_id="HBK5434465.1"
                     /translation="MVKKQITGEEIKRIIEEENVRFLRLMFTDILGTIKNVEVPVSQI
                     DKVLENKMMFDGSSIEGFVRIEESDMYLYPDLSTWMIFPWESAHGKVARLICDIYNPD
                     GTPFAGDPRGNLKRALKDMRDLGFTSFNLGPEPEFFLFKLDEDGGITTTLNDKGGYFD
                     FAPTDLGENCRRDIVLELESLGFEVEASHHEVAPGQHEIDFKYADVVDACDNIQTFKL
                     VVKTIARKHGLHATFMPKPLFGINGSGMHCNMSLFNDEGNVFYDKDGELELSETAYHF
                     LGGLLKHARAYTAVCNPTVNSYKRLVPGYEAPVYVAWSGRNRSPLVRVPESRGLSTRL
                     ELRSVDPSANPYLAMAVLLQAGLDGIRNQITPPAAVDRNIYVMDEEEREAAHIQDLPS
                     TIHNAIKELRKDNVMIDALGQHIFSNFVEAKRLEWAAFRQTVSEWEREQYLELY"
     gene            3165..4775
                     /locus_tag="LLC22_001176"
     CDS             3165..4775
                     /locus_tag="LLC22_001176"
                     /EC_number="6.3.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170456.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CTP synthase"
                     /protein_id="HBK5434466.1"
                     /translation="MTKYIFVTGGVVSSIGKGIVAASLGRLLKNRGLKVTIQKFDPYI
                     NVDPGTMSPYQHGEVFVTDDGAETDLDLGHYERFIDINLNKYSNVTTGKIYSEVLRKE
                     RKGEYLGATVQVIPHITNEIKEKIMRAAKMTDSDVIITEVGGTVGDIESLPFLEALRQ
                     MKADVGTDNVMYIHTTLIPYLKAAGEMKTKPTQHSVKELRGLGIQPNILVVRTEQPVS
                     QSVKNKLAQFCDVEPEAVIESPDVDTLYSIPLVLQAQGMDQIVCDHLKLDTPEADMTE
                     WKELEERVLNLKKKVRIALVGKYVELPDAYISVVEALKHSGFAYNSDIEIDWIKAQEL
                     TRENVEERLKDADGILVPGGFGDRGVEGKIEAIRYARENDVPFLGICLGMQMACVEFA
                     RNVVGLEDASSAETNPDTANNIIDLMADQENIENLGGTLRLGLYPCKIKKGTKTAEAY
                     DGADVVQERHRHRYEFNNKYRQLFEEQGLVFSGVSPDNRLVEIVELPEKKFFVGCQFH
                     PELISRPNRPQKLIKAFVGASLADHETK"
     gene            5067..5936
                     /locus_tag="LLC22_001177"
     CDS             5067..5936
                     /locus_tag="LLC22_001177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010753191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-bisphosphate aldolase"
                     /protein_id="HBK5434467.1"
                     /translation="MPVVSGAEFLKAARKGGYAVGGFNTNNLEWTQAILEAAEAKQAP
                     VLIQTSMGAAKYMGGYKICKDLITDLVEAMNITVPVAIHLDHGDYEAALECIELGYTS
                     VMFDGSHLPFEENLKLAKDVVEKAHAKGISVECEVGSIGGEEDGIIGNGELADIEECK
                     QMVATGIDYLACGIGNIHGQYPENWKGLAFDHLQAIADAVGPDMPLVLHGGSGIPQDQ
                     IEKAISMGISKVNVNTEFQLSFAAATRKYIEAGKDKEGKGFDPRKLLAPGKAAIVEDA
                     KSHIDWFGSANKA"
     gene            6101..7372
                     /locus_tag="LLC22_001178"
     CDS             6101..7372
                     /locus_tag="LLC22_001178"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBK5434468.1"
                     /translation="MKKIVIKGNRPLAGEVTISGAKNSAVALIPAAILADSPVILEGV
                     PDIQDVHSLIEILEIMGATVHFSNNILEIDPREVVSIPMPHGKINSLRASYYFMGTLL
                     GKFGEAVVGLPGGCYLGPRPIDLHVKGFEALGAEVTNEHGAMYLRTENKGLRGNRIFM
                     DVVSVGATINVMLAAVKAKGQTVIENAAREPEIIDVATLLNNMGAKVRGAGTDVIRIE
                     GVETLHGCRHFMIPDRIEAGTYLALAAAVGNGIKVKNVIFEHLESFIAKLQEIGVHMK
                     ISEDEIEVYPSKELKPANIMTYPYPGFATDLQQPLTALLLMTTGTSEIIDTIYAKRVN
                     HVPELARMGADITVEGNMIIVNGPNKLHGTEVVASDLRAGACLVIAGLLAEGTTTIYN
                     VDYILRGYDHIIEKLTALGASIEMIEEVGAE"
     gene            7369..8664
                     /gene="rho"
                     /locus_tag="LLC22_001179"
     CDS             7369..8664
                     /gene="rho"
                     /locus_tag="LLC22_001179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination factor Rho"
                     /protein_id="HBK5434469.1"
                     /translation="MSDYLTMAELENKTLKEVYSYAKEFKIPYYSKMNKKELSLAVIR
                     AQAEKQGFYYMEGILDIVGQDGYGFLRPINYGPSAEDIYISASQIRRFSLRNGDKVAG
                     KARPPKESERYYGLMHVESVNGKDPEEAKERPHFPALTPLYPQRQLQLETTPQRLSTR
                     MIDIFSPIGFGQRGLIVAPPKAGKTSVLKEIANGITENYPEVELIVLLIDERPEEVTD
                     LERSVKGDVVSSTFDLQPQNHTRVSELVLERAMRLVEDKRDVVILMDSITRLARAYNL
                     VVPPSGRTLSGGIDPAALYKPKKFFGAARNIEEGGSLTILATALVDTGSRMDDVIYEE
                     FKGTGNLELQLSRELSERRIFPAIDIKKSGTRKEELLMPSEELEEIWKLRKNMTGDSL
                     EYTEQLIRFLRKTKNNQQFFKEFQDVSFGKKNPTRNLKR"
     gene            8763..9026
                     /locus_tag="LLC22_001180"
     CDS             8763..9026
                     /locus_tag="LLC22_001180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016174397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type B 50S ribosomal protein L31"
                     /protein_id="HBK5434470.1"
                     /translation="MKENIHPDYHPVVFMDSTTGFKFLSGSTKTSQETVEWEDGNTYP
                     VIRVEVTSDSHPFYTGRQKFTQADGRVDRFNKKYGLKDANAAE"
     gene            9471..9920
                     /locus_tag="LLC22_001181"
     CDS             9471..9920
                     /locus_tag="LLC22_001181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5434471.1"
                     /translation="MRFDQLIAEELIVFDPLIDSKGSLFERIGDVLKKTNKVRNVQKV
                     VKALFKREEEISTGIEDGFGIPHAKSKYVTKPALCFFHTAKLTDYSGIDEMPIEYIFA
                     IVVPEKSADMHLEILSTLSRRLMNADFRKGIKEATTPADIIRQISQE"
     gene            9977..11395
                     /locus_tag="LLC22_001182"
     CDS             9977..11395
                     /locus_tag="LLC22_001182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5434472.1"
                     /translation="MKIVGVTACPTGIAHTYMSAEKLEVTARNLNHQAKFETQGVKTE
                     NQLSEQEIKEADAIILAVDKEIELDRFAGKKVKRVSTSRAIKEPQVVIDEALRDIGVF
                     VVSNEKEPAANEKKPTIYNHFMNGVNYMLPFVIAGGIIIALSFAFGITAADPNSADYN
                     VLAAAFSRIGGDTAFAMMVPALGAGIATSIAGKAGFAPGIVAGLLASTGGSGFLGGMI
                     GGVLAGYICDFLANKISVKKEFSAIYQLIVVPFLSILIIGLLMVFVIEQPITWVLDAL
                     TNWLNSLGNTSGLLFGLLIGIMMAADMGGPINKSTSTFSIGLMSAGVNAPIAACMAAG
                     MTPPLGIALATLLFKHKFTKEERTSGQSCWILGASYITEGAIPFAVSDPIRVIPSLMT
                     GSAVAAGISMAVGVTSMAPHGGIWVMLIPNVMNNLPMYVLAIASGTVTTAFMLGLLKK
                     TVKEKKQDKWTKNENLTNEVEA"
     gene            11395..12255
                     /locus_tag="LLC22_001183"
     CDS             11395..12255
                     /locus_tag="LLC22_001183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketose-bisphosphate aldolase"
                     /protein_id="HBK5434473.1"
                     /translation="MLYTMKELLKVAKENQFAVPAFNICSYDMMKAIIEEAERLEAPV
                     ILEIHPDEIAYLSDEFVAAVRAYAYTSKLPIVIHLDHGGTIEDVLRAIRNGYSSVMID
                     ASLKSFDDNVQITKKVVALAHAVNVSVEAELGTIGNNGSAEGGAETIIYTDPDQAKIF
                     VKETGIDTLAVAIGTAHGLYPKNRTPKLNIDLLKELNQQIDLPFVLHGGSGNPDAEVS
                     EAVKYGVAKVNLSSDLKSVFFNALREILSENPSMYEPNAIYPAANKKVQEVVKHKMEI
                     LNTVGKASLY"
     gene            12429..13202
                     /locus_tag="LLC22_001184"
     CDS             12429..13202
                     /locus_tag="LLC22_001184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5434474.1"
                     /translation="MLNEVENRQQEIVNYLKNNQFARVTDLIELVNYSEATIKRDLVF
                     LEKSGLIRRVRGGAMLIDNRKIDVPYLMKITKLEEETEKRKIADTASSLIRDDMVLFL
                     DSSTTSLHLVRNLARFDGLQIITNGIVTAAMLSEYTTAKVSVLGGAIVPKRATINGSK
                     AYNDALSYYADLAIMSCRGLDFSQGVTETHEGEAMVKKAFRKQSDRLAVLVTQQKIAH
                     KFMHQAIAFHEIDYLVTSKELTKEQYAKVKEHHIECLYG"
     gene            13349..13714
                     /locus_tag="LLC22_001185"
     CDS             13349..13714
                     /locus_tag="LLC22_001185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2512 family protein"
                     /protein_id="HBK5434475.1"
                     /translation="MKHVKALVVKAIMIWAILWVVLTGLYGVSFMDSTIVGVIIVVMI
                     YVLGDLLILRKVGNIAATIADAGSAAVILWLYLYFMNDTVDIWMKVLIPALLIGVAEW
                     FFHKWLLSQGIVPDERKME"
     gene            complement(13862..15070)
                     /locus_tag="LLC22_001186"
     CDS             complement(13862..15070)
                     /locus_tag="LLC22_001186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5434476.1"
                     /translation="MEKKLFNKYFIGITLINFIVYLIYYLLMVIMAVIAQDTLHASLS
                     QAGFASGIYIIGTLLARLFMGKQLELFGRKFTLRGGAIFYLLSTLAYLYTPTIGALYL
                     VRFLNGFGYGTVSTATNAIVTAYIPASKKGEGINYYGLSTSLAAAVGPFLGMILLNMT
                     DFRFIIWFSIVLVFFVTIACLVFPVKNIPLSEEQKISLRSWNINSFIEKKALFITGIA
                     FLMGLSYSSVLSFLSSYTKVIHLVAAGSFFFVVYALVITFTRPLTGRIFDVKGEQYVM
                     YPSYLFLTAGLFLLSVTTNSVTLLISGALVGLGYGTFMSNGQAVCLKIVREHRISIAL
                     STYFIGLDLGLGVGPYLMGMLKSLTSFRGLYVIAGVIPLICTALYLVNGRKHSHEAEG
                     ELIESLKNEI"
     gene            complement(15089..15367)
                     /locus_tag="LLC22_001187"
     CDS             complement(15089..15367)
                     /locus_tag="LLC22_001187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434477.1"
                     /translation="MNYWMNTIINRLETAYQTRFDMKASLVFLNDAYQNSIELIKAVD
                     ENPTNECEEFLNLFMSTRDLFIRQLVDRYPSNYHDVEVQIQKLKAYSA"
     gene            15521..16216
                     /locus_tag="LLC22_001188"
     CDS             15521..16216
                     /locus_tag="LLC22_001188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK5434478.1"
                     /translation="MIFLDESLDGGASLDSRVLKEYLDKNDFPIIRKGYHKYLTFEGM
                     EDSHTYILKEGTVKASVISNDGREFNLRYIKDLEIVSLLKDEYSQFIDSPYNIRVESE
                     YAEFYRINRVRFWQNINQDPKLQHYVKEYYRYRLLYSMKKMQQMLLNGKLGAVCTQLY
                     ELYDLFGVRTEEGMLIDFSITNEEIAKFCGISTASSVNRILKQLKKDGIITVKDHHIV
                     ILNMDLLEDNIIF"
     gene            complement(16658..17455)
                     /locus_tag="LLC22_001189"
     CDS             complement(16658..17455)
                     /locus_tag="LLC22_001189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TPM domain-containing protein"
                     /protein_id="HBK5434479.1"
                     /translation="MMKKFFLFFLLLVSVGWPVATHADTATVNDEAGLFTTDQIQSLE
                     QQAEKLNEKIKGRVLIVTTTSNSEEPRDFADNYLRDAVGNDQNGSVLLLDMGQREIYI
                     STSGNMIDYLTDSRIDSILDDVYDQMTNAAYYNAAKAYLSKSATYVEDGVPGGHYRVD
                     EETGKITRYKVLTTVEIIIAVVLALILSLVFYFVTVSRYQLKSGIYKYPFREKSSIKL
                     TEKTDRLTNSFVTTRRIPKSPPPGSGGGGSTTHSSGGGTFGGGGRSF"
     gene            complement(17452..18636)
                     /locus_tag="LLC22_001190"
     CDS             complement(17452..18636)
                     /locus_tag="LLC22_001190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TFIIB-type zinc ribbon-containing protein"
                     /protein_id="HBK5434480.1"
                     /translation="MDVLTHKCPNCGGPLTFDPKDQKFHCEYCLNIYTEEEVSQYEQK
                     QKEARMAGEESKEEPSPTEDFTFTAQEQLADMNEAERKAVDEAGGFSDTADESADNTA
                     AIDLFLCPNCGAEIVTDATTAATYCYYCHNPVVLSGRLSGEFLPNKVLPFAVEKEEAI
                     NRFLAWTKKKWFVPKAFFNKDQIDKLTGVYFPYWATDAEVDGAMQANGTVIRIWRIGD
                     IEYTETKQFAVSRAGKLSFKELVKNALSKNTQQKMVEGVQPFPLDKAIDFKSQYLAGF
                     QAEKRDIEYEAIKSQIQSELKDYSEKLLKDTANGYTTLTGVRTSASITNEVNNYVLLP
                     VWLVTYRSNDSSKKVYYYAMNGQTGKVSGVLPISQKKLGLTALGIFAGLAILFLIGGY
                     LI"
     gene            complement(18661..19908)
                     /locus_tag="LLC22_001191"
     CDS             complement(18661..19908)
                     /locus_tag="LLC22_001191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SPFH domain-containing protein"
                     /protein_id="HBK5434481.1"
                     /translation="MGLIKAATSMVGGGLADQWLEVIEPDNMSDTTVMTKGVKVRKDD
                     KRGSNRKGTEDVLTDGTVVHVYPNMMMLLVDGGKIIDYTAEEGYYTIKNDAAPSMFNG
                     TLKEAIAETFDRFKFGGVTPQKQQVFYINLQEIKGIKFGTSAPLNYFDNFYNAELFLR
                     AHGTYSIHVVDPILFYTNAIPKNKTQVEINDINEQYLAEFLTALQSAINQMSADGQRI
                     SYVPSKSLELSKYMDTALDDSWRELRGMEIVSVAVASISYTDDSVKLINMRNEGAMLG
                     DPSVREGYVQGSIARGMEAAGKNEAGAMTGFMGVGMGMNANGSYLSQAAQNNQEQIKQ
                     QAEKQNQQTAQGNADTWTCPVCGTENSGKFCSNCGAAKPVENVQPKLQMRCSECNEIV
                     DLSNGIPKFCPNCGKPFKGIPVN"
     gene            20123..21868
                     /gene="dnaX"
                     /locus_tag="LLC22_001192"
     CDS             20123..21868
                     /gene="dnaX"
                     /locus_tag="LLC22_001192"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit gamma/tau"
                     /protein_id="HBK5434482.1"
                     /translation="MAYQALYRVWRSQRFEDIVGQKAVTQTLKNAIVSHKTSHAYLFT
                     GPRGTGKTSAAKIFAKAINCPNSKDGEPCNECEMCRSITAGTQEDVIEIDAASNNGVE
                     EIRFIRDRANYAPTKAAYKVYIIDEVHMLSTGAFNALLKTLEEPKESVIFILATTEPH
                     KIPATIISRTQRFDFKRINTADIVEHLEFILKESTISYEPAALNVIARSAEGGMRDAL
                     SILDQAISFSEGTITLDDAMQVTGSLTDEMMDSYLSACVKKEVPEALETLNQILAAGK
                     ESRRFLEDMLQYCRDLLMYQQAPNLVEEQSSTIRSTFTELAQTVSADQLFSMIKILSD
                     TQNEIRFTNSAAIYLEVATVKLAQLPSASVPSADVAFADDQIVKQLQQEIKELRNEIK
                     ELRSNTGIENTKVQPVQQTNHKKQTSTYRVPTERVYKVLREATRQHLNQVKEVWEDLL
                     MSLSVTQRAMLKASEPVAAGPTGLVIAFDYEIVCQRAANDEELQLSVHNNLSRMIKDY
                     APDPVYITRESWPELRRNYLTQAQEEGTENSFASEDSEGEIELLPQEQEVPEETLVVK
                     AEELFGSEAVTVVDD"
     gene            21888..22202
                     /locus_tag="LLC22_001193"
     CDS             21888..22202
                     /locus_tag="LLC22_001193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YbaB/EbfC family nucleoid-associated protein"
                     /protein_id="HBK5434483.1"
                     /translation="MMRGMGNMQGMMKQVQKMQKEMAEAQELLNKTEFTGKATNELVK
                     AVFTGDRRMKDIQINEEVVDPDDIEMLQDLVVMAVNDAIAQIDVETEKKLGKYAKGLP
                     GF"
     gene            22227..22823
                     /gene="recR"
                     /locus_tag="LLC22_001194"
     CDS             22227..22823
                     /gene="recR"
                     /locus_tag="LLC22_001194"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329007.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination protein RecR"
                     /protein_id="HBK5434484.1"
                     /translation="MQYPEPIAKLIDSYMKLPGIGQKTATRLAFYTIDMKDEVVNEFA
                     KSLLSVKRDLHFCSICGNITEEDPCEICRNPSRDRSVILVVEEPKDVMAMEKMREYHG
                     LYHVLHGVLSPMEGTGPEDINISSLLQRLHDADVKEVIIATNATTEGEATAMYLSRLI
                     KPAGIKVTRLAHGLSVGSDIEYADEVTLLKAVEGRREL"
     gene            22887..23531
                     /locus_tag="LLC22_001195"
     CDS             22887..23531
                     /locus_tag="LLC22_001195"
                     /EC_number="2.7.4.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327184.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTMP kinase"
                     /protein_id="HBK5434485.1"
                     /translation="MNGLFITIEGPDGAGKTSILNELYPLLKEVAKTEIIQTREPGGI
                     PIAEEIRAVILDPKNDRMDERTEALLYAAARRQHLVEKVLPALAKGKIVLCDRFVDSS
                     LAYQGAGRRIGVTEIARLNEFATEGTTPDFTLYLDVDSDTGLRRIKKNRQNQIDRLDS
                     EGLEFHQRVRHAYLKLAEENPERIHKVDARKSFEEVLQTSYHTIIEQYPQFFEN"
     gene            23546..23875
                     /locus_tag="LLC22_001196"
     CDS             23546..23875
                     /locus_tag="LLC22_001196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cyclic-di-AMP receptor"
                     /protein_id="HBK5434486.1"
                     /translation="MKIILAIIQDKDSNRLSNELIDANIRATKLSSTGGFLKAGNSTF
                     IVGIEDDRVEEALEIIKKTCESRKQFVSTPVTLDISMDGGVPYPVEVEVGGATVFVLP
                     VEGFHQF"
     gene            23889..24827
                     /gene="holB"
                     /locus_tag="LLC22_001197"
     CDS             23889..24827
                     /gene="holB"
                     /locus_tag="LLC22_001197"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300512.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit delta'"
                     /protein_id="HBK5434487.1"
                     /translation="MNQEINLAQMQPIVYQQLQRSFEHGRIAHAYLFEGEKGTGKHEV
                     GIWLAQHLFCTQMKDNLPCGKCNNCQRIEKKEHPDVLVIEPEGQTIKVDQIRRLQTEF
                     SRSGYESRKKVFLIKEAEKMNSSAANSLLKFLEEPPGDFLAVLETDAVGRILPTIQSR
                     CQVLHFQELSKEALIHRLQEEQIPLEKAKLLAFLTNSLGKAVEISQDEWFNDAKDLIY
                     QWFVYLQKQDTQAFIYVQKKLVKSFKEKTQQFTGLSVLMFYYQEAQRQAVANGEYGKV
                     KQINQIIERILIAEQKLRSNVSFQAVAEQFVLHTIF"
     gene            24863..25687
                     /locus_tag="LLC22_001198"
     CDS             24863..25687
                     /locus_tag="LLC22_001198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332104.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="stage 0 sporulation family protein"
                     /protein_id="HBK5434488.1"
                     /translation="MVEVVGVRYRDAGHIYYFAPGDSEYVYSDKVLVESQQSLHIATV
                     VLPKKEIDPNDLPEAIRPILHKASQAELEKDKKNKKDAYDALKIAKEKVQLRELEMKM
                     VKAEYTFDRNKLIFSFTADGRIDFRELVKDLAAVFRTRIELRQIGVRDEAKIIGGIGP
                     CGRPLCCSSFLGDFVPVSIKMAKDQSLSLNPTKISGLCGRLMCCLQYESEEYETAKKE
                     LPDFGKVIATPDGKGKVVGLNLLSRIVSIRLTGRENPVEYEWDELKEFIQVGEMNG"
     gene            25680..26027
                     /locus_tag="LLC22_001199"
     CDS             25680..26027
                     /locus_tag="LLC22_001199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication initiation control protein YabA"
                     /protein_id="HBK5434489.1"
                     /translation="MDKRSLYDGLNQLESELRNTLTELVEMKHALHEIVEKNTTLEME
                     NQRLREHLRELNQVAQAPAENVKQELSKSRMNLEKIYEEGFHVCYDLYGSRRDNDEPC
                     AFCLEVIYRESGR"
     gene            26096..26968
                     /gene="rsmI"
                     /locus_tag="LLC22_001200"
     CDS             26096..26968
                     /gene="rsmI"
                     /locus_tag="LLC22_001200"
                     /EC_number="2.1.1.198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA
                     (cytidine(1402)-2'-O)-methyltransferase"
                     /protein_id="HBK5434490.1"
                     /translation="MYNQKSFKGNPVYGDLYLVPTPIGNLEDMSYRSVRMLQESDLIA
                     SEDTRNTQKLLNHFEIHTPQKSLHEHNYKERVPQLIALLKEGKTIAQVSDAGMPSISD
                     PGHELVLACIKEGISVISIPGPTAGMTALIASGLVPQPFLFYGFLPRKKKEQKETLKK
                     LKEQTVTLIFYESPYRITATLTNFLEIFGNRQVVLCRELTKVHEEYLRGSTEELLAYI
                     EEHPVKGECCLLVEGNLFEMPVTEVDEELGTLKEQVEAKIASGEKPNAAIKAVALKNG
                     LKKQEVYRQYHELD"
     gene            27077..28198
                     /gene="dinB"
                     /locus_tag="LLC22_001201"
     CDS             27077..28198
                     /gene="dinB"
                     /locus_tag="LLC22_001201"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase IV"
                     /protein_id="HBK5434491.1"
                     /translation="MMELQFPLHNDTSRKIIHIDMDAFFASVEERDHPEFRGHPLVIA
                     RHPSDTGGRGVVTTANYEARKFGIHSAMSAQKAYELCPQAIFKPGDHHKYSDISKQVR
                     EVFYRYTDIVEPVSIDEAYLDVTENKINCKSAIKIARMIQADIWESVQLTCSAGVSYN
                     KFLAKLASDYQKPRGITVVAPQDAVPFLKALPIEKFHGVGKKTVPRMHELGIYTGKDL
                     YECTEMMLIRNFGKMGYSLYRKVRGIHDSPVNVTRERKSVGKEHTYGQPLQTEEAVLT
                     QLRQLAEKVEEALRRVQKHGKTVVLKVRYTDYSTVTKRVTLPEYIYKKEALFYQASLI
                     WEEILGVEKGIRLLGITLTNLDPMTYENIVLPLWENQEI"
     gene            complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LLC22_001202"
     CDS             complement(28252..28854)
                     /gene="nrdG"
                     /locus_tag="LLC22_001202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase
                     activating protein"
                     /protein_id="HBK5434492.1"
                     /translation="MRNPKPKEWLAKDYSQNYIADYKPFNFVDGEGVRNSLYVSGCLF
                     ACEGCFNKAAQNFRYGKPFTPELEEQIIADLRNDYVQGLTLLGGEPFLNTDVCLQVVR
                     RIRKEFGTTKDIWSWTGYTFDELLQDSEDKLELLSQIDILVDGRFELSKRDLKLQFRG
                     SSNQRIIDVQKSLESNQVVIWEKCTDATETYEQIKKQDLI"
     gene            complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LLC22_001203"
     CDS             complement(29169..31358)
                     /gene="nrdD"
                     /locus_tag="LLC22_001203"
                     /EC_number="1.17.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="anaerobic ribonucleoside-triphosphate reductase"
                     /protein_id="HBK5434493.1"
                     /translation="MKVNYEEKTVVTQQPETSQMKVIKRDGRHVDFDEQKINEALIKA
                     EKKIHGSLSPLTYEKIQMIADLVVQEIKSRFAENVKIYEIQNIVEHILLEKNEYELAE
                     EYINYRTKRDFARSKATDINFSIEKLINKDQTVVNENANKDSNVFNTQRDLTAGIVGK
                     SIGLKMLPPHIANAHQKGDIHYHDLDYHPYTPMTNCCLIDFKGMLNNGFKIGNAEVES
                     PKSIQTATAQISQIIANVASSQYGGCSADRTDELLAPFAELNYKKHLKDAEEWIDSPE
                     RQKEYAKAKTKKDIFDAMQSLEYEINTLFTSNGQTPFTSLGFGLGENWFEREIQKAIL
                     QIRINGLGSEKRTAIFPKLIFTLKKGVNLNPEDPNYDIKQLALECATKRMYPDILNYD
                     KIVELTGSFKVPMGCRSFLQGWKDENGQEVNVGRMNLGVVTLNLPRIAIESKGDQNKF
                     WQLLSDRLEIMKDALLYRVERCKEAIPANAPILYMYGAFGKRLSRTDSVNELFKNRRA
                     TVSLGYIGLYEVASAFFGGEWETNPEAKAFTLDIVKELKANADAWGDEYGYHFSVYST
                     PSESLTDRFCRLDTEKFGIIENITDKEYYTNSFHYDVRKNPTPFEKLEFEKDYPKYCS
                     GGFIHYCEYPMLQQNPKALEAVWDFAYDKIGYLGTNTPIDHCYQCGFEGDFKPTERGF
                     ECPECGNHDPKTCDVVKRTCGYLGNPQARPMVHGRHKEISSRVKHMK"
     gene            31657..32451
                     /locus_tag="LLC22_001204"
     CDS             31657..32451
                     /locus_tag="LLC22_001204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318288.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434494.1"
                     /translation="MKNERGGEELEKMIEVKHLSKSYGSKLSPVKALDNISFTVEEGE
                     FVGIMGPSGAGKTTLMNILSTINLPTMGSVSIQGKEITKMKNSELSDFRRKKLGFIFQ
                     EFNLIDTLNAKDNILLPLAVERMTKEEMEKRVRHVAQLLNIEELLKRYPDELSVGQRQ
                     RIAAARALVVQPQVIFADEPTGSLDSKSATELLNYLKTMNQKEKATILLVTHDPYTAS
                     YCDRILFIKDGVIFSEVVRRGTRREFFEKVIDMQATIGGGGKMNAV"
     gene            32441..34483
                     /locus_tag="LLC22_001205"
     CDS             32441..34483
                     /locus_tag="LLC22_001205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288087.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434495.1"
                     /translation="MLYKLAVKSFFRQSRGYLVYFFSLTLSVMIYYSFSAMTYDQSLV
                     RRASQDTSIDGGLSFGGFIITVVLLFFVFSANRFFLNRRQKEIGIYQLFGMNKLQISG
                     IYVLEIMIIGLFACISGILLGIIFSKLFSMILVRMMDMDLTSPFFISIPSVVDTLFAF
                     FIILLAVSVYSIWKIWRYPMIRSFGEKEQADSSTMRFRTRHRLLAVIGLLLLTSGYFG
                     ASHFREITSWMISYHYLDTLVFFFPFLIFFVCVVGTYLFFCYTFRLFLIILSKWKIYY
                     YGINFLIMGNTQVHLLKSWRTNSLITVILGISLMTIGGTASISTILSYQEKVSSPMDY
                     QFDVETEKKIKPILAEEGQKITKEITLHYKVIGSIYSQNLEEPMFQTANLITETQYQA
                     FRKVNPDLPNISLKSPGHTVLLDQMQTLFRNISLYGSSIGLPDNQELKIQQMLPSVLG
                     DETMVYLSPVLIVDDTVFEKAKGVDYQVVNVDVSGGNNEKIDERLSNDLSIKWLNAVY
                     YSYDIVNGSLQGEISTKKLPDDQMKEAQFSQESSRLNFSSSYSKLRAVNRRIGINIFV
                     TLFVGMIVIIATGSILTVRQLAEAEEEKENYHLLTKLGIPQRRIRRMIFEQNALTFFP
                     PMILGITHAVFAINVFTQYIKTADYWLAYLVSGLLILIYLLLYVITSQLYCRIIEE"
     gene            34764..34913
                     /locus_tag="LLC22_001206"
     CDS             34764..34913
                     /locus_tag="LLC22_001206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338698.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="teichoic acid D-Ala incorporation-associated
                     protein DltX"
                     /protein_id="HBK5434496.1"
                     /translation="MNKWRSNPKLNYWGKFIIRTIFYSAVLLFLIYLYHYKNIQGGTF
                     IYNEF"
     gene            34924..36438
                     /gene="dltA"
                     /locus_tag="LLC22_001207"
     CDS             34924..36438
                     /gene="dltA"
                     /locus_tag="LLC22_001207"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltA"
                     /protein_id="HBK5434497.1"
                     /translation="MEIKTIIEAIDDWGINEPDRVAYQADETHTFGELKQASDALAYY
                     LEKKVEGDGPIVVFGNLEFEMIVSFLGVVKSGHAYLPIEEHTPKERILSIFRVAKPSM
                     VISIGDWIEDIPSVPVITKKEFQEIKKIPVGFYPRNSVKGTENFYIIFTSGTTGEPKG
                     VQISHDNLVSFVQWTMEDFGIKPGMHFLAQAPFSFDLSVFSIYPALVSGGMLKPLNKA
                     VVQDFRQLFATLPALKLNVWVSTPSFMDICLMEPTFNGENVPELDMFLFCGEELTKKT
                     AESLLDRFPNARIYNTYGPTEATVAISSIQIDQHVLDSYDRLPIGYVKKDTKVSIVQE
                     GKPVSKGETGEIIIAGPSVSKGYLNNPEKTAAAFFCQNDLASYHTGDAGRLDEYGLLF
                     YEGRMDQQVKLHGYRIELGDIEHYLLQDNRIKQAVVVPKYQGTKVQQLVAFVVLENKT
                     KQPDFQLTKSIKEQLLEVVMDYMIPQKFHYVDLLPQTVNGKIDRKKLTAEVNPE"
     gene            36435..37640
                     /gene="dltB"
                     /locus_tag="LLC22_001208"
     CDS             36435..37640
                     /gene="dltB"
                     /locus_tag="LLC22_001208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltB"
                     /protein_id="HBK5434498.1"
                     /translation="MMLPHMIPYAEPFYFFLLAIALVPIVLSLLIWEKRLPVYQSAVT
                     LFFLFVSFGGNYWQQGAALIGYVLWQTILVWGYFVYRQRKNQTGWFFAAVILAIIPLF
                     LTKVTPFFEHGKASLLGFLGISYLTFKSVQMIMEIRDGMIKTYKPFRYIQFLLFFPTI
                     SSGPIDRYRRFEKDQLHPPVRDKYVDLLGKGVQNIFVGFLYKFIIGYYFGQVLLPVVG
                     RIALQHGGISWALVGYMYVYSMYLFFDFAGYSLFAVGTSYMMGYQTPINFNKPFLSWN
                     IKEFWNRWHMTLSFWFRDYVYMRLMFFMMKKKFFKSKIVMSNIGYFALFLLMGIWHGL
                     TWYYIVYGLYHACLICLTDAWIRFKKKHKEQLPSNKFTHGLAVFLTFQAVCFSFLIFS
                     GFLDKLFFS"
     gene            37685..37918
                     /gene="dltC"
                     /locus_tag="LLC22_001209"
     CDS             37685..37918
                     /gene="dltC"
                     /locus_tag="LLC22_001209"
                     /EC_number="6.1.1.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--poly(phosphoribitol) ligase subunit
                     DltC"
                     /protein_id="HBK5434499.1"
                     /translation="MEEQILSILEEITGTDEVRKNRDIDLFDEGLLDSLASVQLLVEL
                     DGELDIQVPVSEFEREDWSTPNKIIQQATALKG"
     gene            37921..>39181
                     /gene="dltD"
                     /locus_tag="LLC22_001210"
     CDS             37921..>39181
                     /gene="dltD"
                     /locus_tag="LLC22_001210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-lipoteichoic acid biosynthesis protein
                     DltD"
                     /protein_id="HBK5434500.1"
                     /translation="MKKKLFAIFGPVVLAVGLLFVFFTSSYQVDISNPETIRRASSSM
                     SVNVLKGDAIKNYALSEKQYIPFFGSSELSRISPFHPSVLAEKYQRNYRPFLLGAPGT
                     QSLSQYMMMRSAGDAMKNKKVVFIISPQWFVKNGVKTDYFNTYYSELQTYDWLFSMKK
                     VTPADRYLARRLLTFSKVKENDTLTAILQTIKKGKLPLPESLNQLRSQWNMLKREDEV
                     FSNIGLKDRQQKIDHESKRLPKQYQETELSILANQIGERETTNNPFGLKNDFYTHRIR
                     AHEPELKQSQKNWDYRFSPEFSDFQLVLDQLAKNHNEVLFIIPPVNEKWSDYTGLSQE
                     MLQGFAKKIKFQLNSQGFNRIADFVNQAGTNYFMEDTIHLGWKGWLAADQQIRPFLEE
                     NHITASKYHLDDAFFSKSWQHQIPDKLQ"
BASE COUNT        12584 a         6891 c         8188 g        11518 t
ORIGIN      
        1 aataaaaaca ctaataaagg atagtacagt ataataaaaa ataaaaggta tctggtacga
       61 aaatcaacta gatacctttt ttgtgttctt atttttttgt tattttataa aaaatagaga
      121 tctcatgtta gaaaacctaa catatgcagt tgacaatatt ttttttaatt ggtacacttt
      181 agccaactta taaaacgaaa ggggacgtct gatgggagaa aaggaattgc gccgatctat
      241 gtccgtattt ccaattggta cagttatgaa gctgactgat ttgtctgctc ggcaaattcg
      301 ctattatgaa gaacaagatt tagttcatcc ggaacgaagc gaaggaaacc gacgtatgta
      361 ttcgctgaat gatattgata tgttgcttga gattaaagac tatctttcag agggattgaa
      421 tatggctggg atcaaacgtg tatacgaaat ggcacaggcg aaaaaacaag aagcaaaaaa
      481 caagaagccg ttgacagatc atgacgttcg acaaattttt cgtgatgaga ttttggcgca
      541 aggtgggtta agcaaaacag gtcattatca gtcgcaagga ttgcaaagac aattctttga
      601 ctgaataaat taaaaaagga agagggatac catggtaaag aaacagataa caggtgaaga
      661 aatcaaacga atcattgagg aagaaaacgt acgattttta cgattgatgt tcacagacat
      721 cttaggtacg atcaaaaatg tagaagttcc agtgagccag atcgacaaag tattagaaaa
      781 taaaatgatg tttgacggtt cttcgattga aggatttgtt cgaattgaag aaagcgatat
      841 gtatttgtat ccagatctct ccacttggat gatcttcccg tgggaaagtg ctcatggaaa
      901 agttgctcgt ttaatttgtg atatctataa tccggatggg acaccatttg ccggcgatcc
      961 tcgcgggaat ttgaaacgag cattgaaaga tatgcgcgac cttggtttta cctctttcaa
     1021 tttaggacct gaaccagaat tcttcttatt taaattagac gaagacggtg ggatcacaac
     1081 gaccttgaat gataaaggtg gttattttga ttttgcacca acagatttag gtgaaaattg
     1141 ccgccgtgac atcgtgttgg aattagaaag tctaggcttt gaagtggaag cttcacatca
     1201 tgaagtagcg ccaggacagc atgaaattga ctttaaatat gcagatgtgg tagatgcttg
     1261 tgataatatc caaaccttca agctcgttgt caaaacgatt gcgcgcaagc atggacttca
     1321 cgcgactttc atgccgaaac cgttatttgg gatcaatggt tctggtatgc attgcaatat
     1381 gtctttgttc aatgatgaag gaaatgtttt ctatgataaa gacggtgaat tggaactaag
     1441 tgaaacagct tatcatttct taggtggttt gctgaaacat gctcgtgcct acacagccgt
     1501 ttgcaatcca acagtcaatt cttataaacg tctcgttcca ggttatgaag cgcctgttta
     1561 tgtcgcatgg agtggccgta atcgttcgcc attagtacgt gtaccagaat ctcgcggttt
     1621 atccacacgt ttggaattgc ggtcagttga tccatctgca aacccatact tggcaatggc
     1681 agtattgttg caagcaggac tagacggtat ccgtaatcag atcacaccgc cagcagctgt
     1741 tgaccgtaac atttatgtaa tggatgagga agaaagagaa gctgcacata tccaggactt
     1801 accttcaact atccataatg ctatcaaaga attgcgtaag gataatgtaa tgattgacgc
     1861 attaggacaa catatcttct caaattttgt tgaagcaaaa cgtctcgaat gggcggcatt
     1921 cagacaaact gtttccgagt gggaaagaga acaatatcta gaactttatt aaaacaggaa
     1981 taccgtgaat tagaggctgt gaaatcagcg ttttgacctg agtattagag aaactaacgg
     2041 aaaaatagtt cctcatattt tgccgttttt tgagctaata ccgagggtca gctgattgaa
     2101 caccgtttag tggagaggtt gtgaaaaagc tgccctgcaa caagtaataa gaatagccaa
     2161 gcaaaaacag cttttcttgt ttttgaattg gctgaactta ttaccgcaga tgcaagcttt
     2221 tgaacaccgt ttaccaagag gttttgaaaa agacgtttag tttcgagtat taagaaaaat
     2281 tttgtgaaaa tggctttcta catttttgca taaatttggc ttaataccga gaaactggct
     2341 tttgaatacc gtttatccag aggttgtgag cctaccattt aactccgaat cacaagaaat
     2401 aatttcaaaa acagcttctc atgtttgatg gatattgtga cttgtgaccg aggagttggc
     2461 aggagaacac cgtttattta gaaataagga ggcacgactt ttgtcgcatc tccttatttt
     2521 ttacttatgt gattcgttac cttcaatgaa tccctacaag gcacttttgt tgaaaaaaag
     2581 gtcatctttg aaaaaattag tggaattgtt ttgtttttga tattatttaa tagaaaagat
     2641 atgccaaaaa tccgagaact gtggactacg ttttttacgt aaaggaggta aataagggtg
     2701 aaagaaaaag attgtttcta cgataagcta tataaactgt tgctgcaagt aggaaaaagt
     2761 agttctttgt taggtgggat attatctatc ataatgtttg ttttattttt ttatctatta
     2821 tttcacttaa aatttttcag taacgatttt ctgatttgct taggtttaac gttagctatg
     2881 tttatatcaa gcttattatg tgggttaaat tttttttgca ctcataaagg acttaagaaa
     2941 taatttctca aaggatatcg aaaaagaaaa aattgtaagc ggatagtatt catttgagta
     3001 cttgactttc ccttagtcag cttgtattat acaccttggg caccctttta gagggtcaga
     3061 agtttacaga aatttcggct ccctattctt attgaagaat agggagcttt gtttattgtc
     3121 tgagactttt cctgcacata aattaaaaag gagtttttga acttatgaca aaatatattt
     3181 ttgtgaccgg cggtgtcgtt tcatcaatcg gaaaagggat tgttgcagct tctttaggac
     3241 gcttattgaa aaaccgcggc ttaaaagtaa ctatccaaaa atttgatcca tacatcaacg
     3301 tggatccggg gacgatgagc ccatatcagc acggagaagt attcgtaaca gatgatggtg
     3361 ctgaaacaga tttggatctg ggccactacg aacgttttat tgacatcaat ttgaacaaat
     3421 actccaacgt gacgacagga aaaatctatt ctgaagtttt gcgtaaagaa cgtaagggcg
     3481 aatacttggg agcaactgtt caagttattc ctcatattac aaatgagatc aaagaaaaaa
     3541 tcatgcgagc agctaaaatg actgattcag atgtgatcat tacagaagta gggggaacag
     3601 taggggatat agaatctttg ccattccttg aagcacttcg tcaaatgaaa gcagatgtcg
     3661 gtacagataa tgttatgtat atccatacaa cattgattcc ttacttgaaa gctgctggag
     3721 aaatgaaaac taaaccaacg cagcacagtg taaaagagct acgtggttta ggtatccaac
     3781 cgaatatttt ggtggtacgt acagagcaac ctgtttctca aagcgtgaaa aacaaattgg
     3841 cacaattttg tgatgtcgaa ccagaagcag ttatcgagtc gccagatgta gatacacttt
     3901 actccatccc attagtttta caagcacaag gaatggatca aattgtttgc gaccatttaa
     3961 aactagatac accagaagca gacatgacag aatggaaaga attagaagaa cgtgtcttga
     4021 acttgaagaa aaaagtacgg attgcgcttg tcggtaaata tgtcgagtta ccagatgcat
     4081 atatctcagt agttgaagca ttgaaacatt ctggtttcgc ctataattca gacatcgaga
     4141 tcgattggat caaagcacaa gaattaacga gagaaaatgt agaagaacgt ttgaaagacg
     4201 cagatggaat cttggttcct ggtggatttg gtgatcgcgg agtagaaggg aaaatcgaag
     4261 cgattcgtta tgctcgcgaa aatgacgttc cgtttttagg tatttgtctt ggtatgcaga
     4321 tggcttgtgt cgaatttgca cgtaacgtcg ttggattaga agatgcgtca tcagctgaaa
     4381 cgaatccaga tacagcaaac aatattattg atttaatggc tgatcaggaa aacatcgaga
     4441 atttgggtgg aactttacgc cttggattat acccatgtaa aatcaaaaaa ggaacgaaga
     4501 cggctgaagc atatgatgga gccgatgttg tgcaagaacg tcaccgtcac cgctatgagt
     4561 tcaataacaa atatcgtcaa ttgtttgaag aacaagggct agtcttttca ggtgtctcac
     4621 cagataaccg tttagtagaa atcgtagagc tgccagagaa aaaattcttt gtgggatgcc
     4681 aattccaccc agaattgatt tctcgtccaa atcgcccgca aaaattaatc aaagcatttg
     4741 tcggagcatc attagcagat cacgaaacaa aataattttt gaacttgata gaaagagaaa
     4801 agtagcaaga gaaggggata agcaattttc ttgtcacttt tctctttttc tgatttgtta
     4861 ttatttgtag gaaaaaagat agaaagcaaa agactttttt cgattaaagc gctattggat
     4921 attttatttt ttgcaaaaaa cttcttgaaa attttcattt tcattgattt tagtagaaaa
     4981 ctaccgaaat gtttggtaaa atagggtcgt tggttaagaa ttgtcttaac aaatttagtt
     5041 ttacaaaact taggaggaat tttattatgc cagtagtatc aggagctgaa tttttaaaag
     5101 ctgctcgtaa aggcggttac gctgtcggcg gattcaacac aaacaacttg gaatggactc
     5161 aagcaatcct tgaagcggct gaagcaaaac aagcaccagt acttatccaa acatcaatgg
     5221 gtgcagctaa atacatgggt ggttacaaaa tctgtaaaga tttaatcact gatttagttg
     5281 aagcaatgaa catcactgtt ccagttgcta tccacttaga ccatggtgat tacgaagctg
     5341 ctttggaatg tatcgaatta ggctatactt cagtaatgtt cgatggttca catctaccat
     5401 ttgaagaaaa cttgaaatta gctaaagacg ttgttgaaaa agcacatgca aaaggtatct
     5461 cagttgaatg tgaagttggt tcaatcggcg gagaagaaga cggaatcatc ggtaacggcg
     5521 aattagctga tattgaagaa tgcaaacaaa tggttgctac aggtatcgac tacttagctt
     5581 gcggtatcgg taacatccat ggtcaatatc cagaaaactg gaaaggatta gcttttgacc
     5641 acttacaagc aattgctgat gctgtaggtc cagacatgcc tttagtatta catggcggat
     5701 caggtattcc tcaagatcaa atcgaaaaag ctatctcaat gggtatctca aaagtaaatg
     5761 ttaacactga attccaatta tcatttgctg cagctactcg taaatatatc gaagctggta
     5821 aagataaaga aggtaaagga ttcgaccctc gtaaattatt agctccaggt aaagcagcaa
     5881 tcgttgaaga tgctaaatct catatcgact ggttcggttc agctaacaaa gcgtaagcat
     5941 ccacataaca gatacgatat ataggaatgg agaacgactt ttgaagtcgc tctccattct
     6001 tttttactta aaacggcaga ccatgctcgt ttcttttttt tatctatgat aaaatacaag
     6061 catatccatg aaaaaagatt aataaacaag gtggaaacag atgaaaaaaa tcgtaatcaa
     6121 aggaaaccga cctttagctg gtgaagtaac gatcagcggt gcaaaaaata gtgcagtcgc
     6181 attgattcca gctgcaatct tagctgattc cccagtgatc ttggaaggtg tgccggacat
     6241 acaagatgtt cattcattaa ttgaaatttt agagatcatg ggcgcaactg tccatttttc
     6301 caacaacata ctagaaatcg atcctcgaga agtcgtatcg attccgatgc cgcacggaaa
     6361 aatcaatagt ttgcgtgctt cttattattt tatgggaaca ctgcttggta aatttggcga
     6421 agcggtagta ggcctgccag gtggctgtta tttaggccct agaccgattg acctacacgt
     6481 caaaggattt gaagctctag gtgctgaagt gacaaatgaa catggtgcca tgtatttacg
     6541 gacagaaaat aaaggattgc gtggcaatcg gattttcatg gacgtggttt cagtcggagc
     6601 aacgatcaat gtgatgttag ctgctgtaaa agcaaaagga cagacagtaa ttgaaaacgc
     6661 tgcacgagaa ccggaaatca tagatgtggc aactttactg aataatatgg gggcaaaagt
     6721 tcgaggagcg ggtacagatg tgatccgtat cgaaggagtc gaaacattac atggctgtcg
     6781 gcatttcatg attcctgacc gcatcgaagc aggaacctat ctagcattag cagctgcagt
     6841 aggaaatggt atcaaagtga aaaatgtgat ctttgaacat ttggaaagct ttatagcaaa
     6901 attgcaggaa attggtgtcc atatgaaaat cagcgaagat gaaatcgaag tttacccctc
     6961 gaaagaatta aaacccgcaa acatcatgac ctatccttat ccaggatttg ccacagatct
     7021 gcagcagcca cttactgcgt tactattgat gactacaggc acttcagaaa tcatcgatac
     7081 gatctatgcg aaacgtgtga accatgtgcc ggaactagca cgaatgggcg ctgatattac
     7141 cgtggaagga aatatgatca tcgtgaatgg tccaaataaa cttcacggca cagaagtcgt
     7201 ggcttctgat cttcgggcag gtgcttgttt agtgattgct ggactattgg cagaagggac
     7261 aacgacgatt tacaatgtag attatatctt acgcggttat gatcatatta tcgagaaact
     7321 aacagcctta ggggcatcaa ttgaaatgat agaggaagtg ggagctgaat gagcgattat
     7381 ttgacaatgg cagaactaga gaacaaaacg ttaaaagaag tttatagtta tgccaaagaa
     7441 tttaaaattc cttattacag taagatgaat aaaaaggaat tatctctagc tgtgattcgt
     7501 gcacaagcag agaaacaagg attttattat atggaaggaa tattggatat cgttggtcaa
     7561 gatggttacg gttttttacg gccaatcaat tatggaccaa gtgcagaaga tatctatatt
     7621 tctgcctcac aaatcagacg attcagtttg agaaatgggg acaaagtggc aggaaaagcc
     7681 cgtccaccta aagaatcgga acgttattat ggtttgatgc acgtggaaag cgttaatgga
     7741 aaagatccgg aagaagcaaa agaacgtccg cattttccag ccttaacacc tctttatccg
     7801 caaagacagc ttcaactgga aacaacaccg caaagactat ctacccgaat gatcgatatc
     7861 ttttctccaa tcggttttgg tcagcgtgga ttgatcgtcg caccgccaaa agcagggaaa
     7921 acttctgtat taaaagaaat cgcaaatggt atcaccgaaa actatccgga agtagaatta
     7981 atcgttctac tgattgatga acgaccggaa gaagtaacgg atctagaacg aagcgtgaaa
     8041 ggcgacgtgg tatcttctac atttgatctg cagccgcaaa accatactcg agtttctgaa
     8101 ttagtattgg aacgcgcaat gcgtttagtc gaagataaac gagatgtcgt tatcttgatg
     8161 gatagtatta ctagacttgc tcgggcctat aacttagtcg ttccaccaag cggacgtaca
     8221 ttgagtggcg ggattgaccc agccgcattg tataaaccta agaaattttt cggggcagca
     8281 agaaacatcg aagaaggtgg cagtttgacg attttagcga ccgctttagt cgatacagga
     8341 agccgtatgg atgacgtgat ctatgaagaa ttcaaaggaa ctggaaatct agaattacaa
     8401 ctttcacgtg aattatctga acgtcggatc ttcccagcca tcgatatcaa aaaatcaggt
     8461 acccgaaaag aagaattatt gatgccaagt gaagaattag aagaaatttg gaaacttcga
     8521 aaaaatatga ctggagattc attagaatat acggaacaac tgatccgctt tttgcgtaaa
     8581 acaaaaaaca atcagcaatt tttcaaagaa tttcaagatg tctcctttgg taaaaaaaat
     8641 ccgaccagaa atctgaaaag ataattgcaa ccttgactga aacatgttaa gatgttaatg
     8701 ttgtaaatcg acaaatcaac tctggttcag caaatggagc agggcaaagg agcgaaaaaa
     8761 tcatgaaaga aaacatccat ccagattacc acccagtagt attcatggat tcaacaactg
     8821 gtttcaaatt cttgtcaggt tcaacaaaaa cttcacaaga aacagttgaa tgggaagacg
     8881 gtaatacata cccagtcatc cgtgtcgaag taacttctga ctcacatcca ttctacactg
     8941 gacgtcaaaa attcacacaa gcagacggac gtgtggaccg tttcaacaaa aaatacggtc
     9001 tcaaagacgc aaacgctgcg gaataataaa aacgctgata actcaacgtt tagcagacta
     9061 tctgataggg atagtctgtt tttttatgtt ttttgccaat ttaaaacttc gtttgatgct
     9121 gaaaaagtcg taggatcata atgcacaaaa caatgaaaaa ctagtatata gttttaatta
     9181 tccacttgat aaaaacacct tatattaacg aaatgaagag gggttatttc gaagtaaaaa
     9241 accatttacc taaaattaga agctaagctt tcctttcaag gaaggctttt tgttttgtta
     9301 tagacttgcg attgtttgtg agctagatcg ttcattttaa tgacttatac acgcggatga
     9361 tgggtctttt tcctctgttc attcataata ttgaacggta cagctagcga tgctatactg
     9421 acctcagttc caagaaaacg ttaacatttt ttgtggggga gaggtttttt atgaggtttg
     9481 atcaattgat cgcagaagaa ctgattgttt tcgatccatt gatagattca aaaggatcat
     9541 tatttgagcg aataggggat gtgttgaaaa aaacaaataa ggtaagaaat gttcaaaaag
     9601 tcgttaaggc actattcaaa cgagaggagg agatctccac aggaatagaa gatggatttg
     9661 ggattcccca tgcaaaaagc aaatatgtga caaaaccagc actgtgtttt tttcatacag
     9721 ccaaattaac ggactatagc gggatagatg aaatgccaat tgaatatatt tttgccatcg
     9781 tagttcctga aaaatcagca gatatgcatc tagagattct cagcacactc tccagacgat
     9841 tgatgaatgc agattttaga aagggaataa aagaagccac tacgccagca gatatcatca
     9901 gacagattag tcaagaatga aaatagtaga gtctttgtcc gagtatcgat agtgaagaaa
     9961 aaggaggaaa ataatcatga aaatcgttgg tgtaactgct tgcccgactg gaattgctca
    10021 tacttatatg tcggcagaaa aattagaagt aacagcaaga aatctaaacc atcaagcaaa
    10081 attcgaaaca caaggtgtaa aaacagaaaa tcagttatct gaacaagaaa tcaaagaggc
    10141 agatgcaatc attcttgcag tagataaaga aatcgaattg gaccgatttg ccgggaaaaa
    10201 agtaaagcgt gtctctacaa gccgagcaat caaagaaccg caagtagtaa tagacgaagc
    10261 attgagagat attggcgtat tcgttgtgtc taatgaaaaa gaaccagctg caaatgagaa
    10321 aaagccgaca atctataatc atttcatgaa tggtgtgaat tacatgcttc catttgtgat
    10381 cgcaggcgga atcatcatcg cactgagttt tgcctttggg attacagcgg ctgatcccaa
    10441 ctcagcagac tataatgtgt tagcagctgc attttcaagg atcggaggag atacagcgtt
    10501 tgccatgatg gttcctgcgt taggcgcggg gattgctaca tcgattgctg gaaaagcagg
    10561 ttttgcccca ggaattgttg ccggattact ggcctctaca ggtggttcag gttttcttgg
    10621 cggaatgatt ggtggcgtgc tagcagggta tatctgtgat tttctggcaa ataaaattag
    10681 cgtaaaaaaa gaattttctg ctatttatca gctgattgtc gtcccctttt tatcgatctt
    10741 aattattggg cttttgatgg tatttgtgat tgaacaaccg atcacatggg tgttggatgc
    10801 tttgacaaat tggctgaata gcttgggaaa tacatccggg ctattgttcg gattacttat
    10861 cgggatcatg atggcagctg atatgggtgg gccgatcaat aaatcgactt cgactttctc
    10921 gatcggtttg atgtcagctg gagtaaatgc accgattgct gcttgtatgg ctgcaggaat
    10981 gacacctccc ctaggtattg ctttagccac tttattattc aaacataaat ttaccaaaga
    11041 agaacggact tcaggtcaat catgctggat tttaggcgct tcgtatatta cagaaggtgc
    11101 tataccgttt gcggtatctg acccgatccg cgtgatacct agtttgatga caggttcagc
    11161 agtcgctgca gggatttcca tggcagtagg agttacttca atggcacctc atggagggat
    11221 ttgggtgatg ctaattccaa atgttatgaa caatttacct atgtatgtct tggcaattgc
    11281 atcaggtaca gtcactacag cctttatgct tggactattg aaaaaaacag tgaaagagaa
    11341 aaaacaagac aagtggacga aaaatgaaaa tctaacaaat gaggtggaag cgtaatgtta
    11401 tatacaatga aagagttatt gaaagtggct aaagagaatc aatttgcagt accagccttc
    11461 aatatttgca gctatgatat gatgaaagca atcatcgaag aagcagagag attagaagca
    11521 ccagtaatct tagaaattca tcctgatgaa atcgcctatt taagtgatga gtttgttgcg
    11581 gcagtaagag cctatgctta tacaagtaaa ctgccgatcg ttatccactt ggatcatggc
    11641 ggtacgatag aagatgtctt acgggcgatt cgaaacggct attcttccgt gatgatcgat
    11701 gcgtctttga aatcattcga cgacaatgta cagattacga aaaaagtggt tgcgttagct
    11761 catgcggtaa atgtctcagt ggaggctgag cttggaacga ttgggaataa tggttctgct
    11821 gaaggaggtg ctgaaacaat catttataca gatcctgatc aagcgaagat ttttgtgaaa
    11881 gaaacaggaa tcgatacact tgctgtagca attggaacag cgcatggctt gtatccgaaa
    11941 aacagaactc caaaattaaa tatcgactta ctgaaagaat tgaaccaaca aatcgatctt
    12001 ccatttgttt tacatggcgg ttcaggtaat ccggacgcag aagtcagcga agcagtaaaa
    12061 tacggagttg ccaaagtgaa tttgagctca gatcttaaaa gcgtcttttt caatgctttg
    12121 agagaaatat tgagtgaaaa tccatcgatg tacgagccga atgcaattta tccagcagct
    12181 aataaaaagg tacaagaagt ggtcaaacat aaaatggaaa ttttgaacac agtaggcaag
    12241 gctagtttat actaaaaata aaaatgtgtg gtcaagaggg tatgacaata gtcttgtcat
    12301 accctcttaa ccacacacga tgttcagaag tagttttttc gaaaaatttc ttcttatttc
    12361 tcgaagccaa tcacttctgt cacaacctct tttttcctgt tactatataa agtaaatggg
    12421 gtgattttat gttgaatgaa gtggagaata gacagcagga gattgtgaat tatctaaaaa
    12481 acaaccaatt tgcaagagtc accgatttga tcgagttagt aaattatagc gaagccacga
    12541 ttaaacgtga ccttgttttt ctggaaaaaa gtggattgat ccgtagagtt cgcggtggcg
    12601 ccatgcttat tgacaatcga aaaattgacg tgccttacct gatgaagatc accaaattag
    12661 aagaagaaac agaaaaacgt aagattgcag atacagcttc ttctttgatt cgagatgata
    12721 tggtcttatt cttggattcc agtacaacct ctttacactt agtcagaaac ctagcaagat
    12781 ttgatggttt gcagatcatt acgaatggca tcgtcacagc tgctatgttg agtgaatata
    12841 caacggcaaa agtatctgta ttgggagggg caattgttcc gaaacgagca acaatcaacg
    12901 gttcaaaagc ctataacgat gcattgtcat attatgcgga tttagcgata atgagttgtc
    12961 gcgggctaga tttcagccaa ggagtaacag aaactcatga aggagaggca atggtcaaaa
    13021 aagcttttag aaaacaatca gaccggcttg ccgttttagt tacacagcaa aaaattgcac
    13081 ataaattcat gcatcaagcc attgcttttc atgaaatcga ttatctggtg acaagtaaag
    13141 aactgacaaa agaacagtat gcgaaagtaa aggaacacca tatcgaatgt ctgtacggat
    13201 aaattattac gtgaatgttc taagtggctt cctcattttt agataggacc ttatctttgc
    13261 tcgcttctct cagccgatgg tataataatg aaaaggttat cttgttagat aatcttactt
    13321 ttttatccag gagaaaggag tgcagaaaat gaaacatgtg aaggcgttgg tagtgaaggc
    13381 aatcatgatc tgggcgattc tgtgggtcgt gctgacaggt ttatacggtg ttagctttat
    13441 ggattcaacg attgttgggg taattattgt agtcatgatc tatgtgctag gggatctgtt
    13501 gatcttacgt aaagtaggga acatcgcagc gacgatcgca gatgctggtt cagctgcagt
    13561 tatcttgtgg ctctatctat attttatgaa tgatacagtc gatatttgga tgaaagtatt
    13621 gattcctgct ctattgatcg gtgtggcaga atggttcttc cacaagtggt tgctaagtca
    13681 aggcatcgta ccagatgaac ggaaaatgga ataaatcaac agttaaacta ttcttatcga
    13741 taaatgaaag ctttaaaaat aaatagatgt ttaattaaga ataatcataa actattttta
    13801 ctcaaaaaac cgctcagatt attttcagat ctgaacggtt ttttttatct attcatcaag
    13861 atcaaatttc atttttcaat gattcaatca attcgccctc tgcttcatga ctatgttttc
    13921 ggccattaac aagatagagt gctgtacata tcaatggaat gactccggca atcacataca
    13981 atcctctaaa tgaagtaaga gattttagca tccccatcaa ataaggacca acgcctaagc
    14041 ctaggtctaa accaataaag taggtagata aagcaatact gattcgatgt tcgcggacga
    14101 tttttaaaca aacagcctgt ccatttgaca taaacgtacc ataacctagg ccgactaatg
    14161 ctccagagat aagcaatgtc acactattcg tcgttacact cagtaaaaat aatcctgctg
    14221 ttaagaataa atagctagga tacatcacgt attgttctcc tttgacatcg aaaatccttc
    14281 cagtcaatgg acgtgtaaat gtgatgacca aagcatatac gacgaagaaa aatgacccag
    14341 cagcaactaa gtggattact tttgtataag aagataaaaa tgataaaaca cttgaataag
    14401 aaagacccat caaaaaggca attcctgtaa tgaaaagtgc tttcttttca ataaaactat
    14461 tgatattcca tgagcgaaga gatatttttt gttcttcaga taatggaata ttttttacag
    14521 gaaagacaag gcaggcaatc gtaacaaaga agaccagtac aattgaaaac cagataatga
    14581 aacgaaaatc agtcatattc agcaaaatca ttcctaaaaa tggcccaaca gcggcagcta
    14641 aactagtact taatccataa taattgatgc cttccccttt tttagatgca gggatatatg
    14701 cagtaacgat agcatttgta gctgtagaaa ctgtaccgta gccgaatcca ttcaagaatc
    14761 gaactaaata caatgccccg atagttggcg tataaagata tgctaatgtt gaaaggagat
    14821 agaagatcgc gccgcctctt aaggtaaact tccgaccaaa tagttctaac tgtttcccca
    14881 tgaataagcg tgccagcaat gttccgatga tatagatccc agaagcaaaa cctgcttggc
    14941 tcaagctggc gtgtaaggtg tcttgcgcaa tgactgccat gatgaccatc aacagataat
    15001 aaatcaggta gacaataaaa ttgatcaatg tgattccaat aaaatattta ttaaataatt
    15061 tcttttccat gtatgttata cattcccctt aagctgaata tgcttttaat ttttgtattt
    15121 gaacttctac atcgtgataa ttggatggat agcgatcaac aagttggcga ataaataaat
    15181 ctcttgtaga cataaacaga tttaaaaatt cttcgcattc gtttgttgga ttctcatcca
    15241 ctgctttgat caattcgatc gagttttgat acgcatcatt taaaaagact aaagaagctt
    15301 tcatatcaaa tcttgtttga tatgctgttt ctaatcgatt aatgattgtg ttcatccagt
    15361 aattcatgtt ttttccctct attcttaaaa aattttactt ctgcagtata acgaataaaa
    15421 aaaaggaaaa aaatcgcata agtgatggaa aaaggtactt aacaaatgtt aatatcatta
    15481 gtaaaatacc tttggacttt aaaaagtttt aaagtactgt atgatctttt tagatgaaag
    15541 tttggatggg ggagcatcat tggatagtag agtcttaaag gaatatttgg ataaaaatga
    15601 ttttccgatt atacgcaaag gatatcataa atatttgaca ttcgaaggga tggaagattc
    15661 ccatacgtat atcttgaaag agggaacggt aaaagcaagt gttatttcaa atgatgggag
    15721 agaatttaac cttcgctata tcaaagatct tgaaatcgtc tctcttttaa aagacgaata
    15781 ttcacaattc atcgattcgc cgtataatat tcgagttgaa tcagaatatg cagagtttta
    15841 tcgaatcaat cgtgtgcgct tttggcaaaa tatcaaccaa gacccaaagc tacaacacta
    15901 tgtaaaagag tattaccgct atcgtctgct ttattcgatg aaaaaaatgc agcaaatgct
    15961 attaaacgga aagctgggag ctgtttgtac gcaactttac gaattatatg atttattcgg
    16021 tgtgcggaca gaagaaggga tgctgatcga tttttcgatc acgaatgaag aaatcgccaa
    16081 attttgtggc atctcaactg ctagcagtgt aaacagaatt ttaaaacaac tgaaaaaaga
    16141 tggtattatc accgttaaag accatcatat cgttattttg aatatggact tgttagaaga
    16201 caatattatc ttttgatgaa caaagaggtt gtgaaatcag cgttttgacc tgagtattag
    16261 agaaacaaac ggaaaaatag ttcctcatat tttgccgttt tttgagctaa taccgagggt
    16321 cagctgattg aacaccgttt accaagaggt tgtgagcctg ccgtttaact ctgagtcaca
    16381 aggaacaatt tcaaaaaaca gcttttcatg tttgatgaat attgtgactt gtgaccgagg
    16441 agttggtagg agaacaccgt ttaccaagag gttgtgaaaa agctgttctg catcaagtaa
    16501 taagaagagc caagtaaaaa cagtctctta tgtttttaac ttggctggac ttatcaccgt
    16561 agatgtaagc ttttgaacgc cgtttatttg caacaaaagg ggctgtgaca cgatttttgt
    16621 cacagccctt tttttgcgaa cattcattta gcaattttta gaaacttctg ccgccaccgc
    16681 caaaagtccc gccaccgcta gaatgggtag tacttccgcc accgccgctt ccaggaggtg
    16741 ggcttttggg gattcttctt gtcgtgacaa aagaatttgt cagacgatcg gttttttcag
    16801 ttaatttgat actggatttt tctcggaatg gatatttgta gatgcctgat ttcaattgat
    16861 aacgcgaaac agtcacaaaa taaaagacaa gactaaggat aagagccaaa acaacagcaa
    16921 tgatgatttc tactgtcgtc aaaaccttat agcgtgtaat tttgccagtt tcttcgtcta
    16981 cacgataatg tcctcctgga actccgtctt ccacatatgt tgctgattta gacaggtaag
    17041 cttttgcagc attgtaatag gcagcatttg tcatctgatc ataaacatca tctaagatcg
    17101 aatcgattct gctatcagtc aaataatcga tcatattacc agaagtcgaa atgtagattt
    17161 cacgctgtcc catatctaat agcaatactg agccattttg atcatttccg actgcgtctc
    17221 ttaagtaatt atcagcaaag tctcttggtt cttctgaatt agatgtagtc gttacgatca
    17281 agactcgtcc tttgattttt tcattcagct tttctgcctg ttgttccaaa gattggattt
    17341 gatctgttgt gaataaccca gcctcatcat ttaccgtagc tgtatctgca tgagtagcca
    17401 ccggccagcc aacacttact agcaaaagaa agaataaaaa aaattttttc atcatatcaa
    17461 gtaacctccg atcagaaaga ggatcgctag cccagcgaaa atcccaagag cggtcagtcc
    17521 caattttttc tggctgatcg gcaggacacc gctgaccttt cctgtttgtc cattcattgc
    17581 gtagtagtag acttttttac ttgagtcatt gcttcgataa gtaacaagcc ataccggcag
    17641 taatacgtaa ttatttactt cgtttgtgat tgaagcagaa gttcgcacac cggtcaatgt
    17701 tgtatatcca tttgcggtat cttttaacag cttctctgaa tagtctttta attcagattg
    17761 aatctgtgat ttgattgcct catattcgat atctcttttt tctgcttgga acccggctaa
    17821 atactggctt ttaaaatcaa ttgctttatc taacgggaaa ggttgcacgc cttcgaccat
    17881 cttttgttgc gtattttttg ataaggcatt ttttactagt tctttaaaag aaagcttgcc
    17941 tgctcttgaa acagcaaatt gcttcgtttc tgtgtattcg atgtcaccta tccgccatat
    18001 gcggataact gtaccattcg cctgcatggc accatctact tcagcatctg tagcccaata
    18061 agggaaatac acacctgtca acttatcgat ttgatcctta ttgaaaaaag ctttgggaac
    18121 aaaccatttt ttcttggtcc aagcgagaaa tctgttgatt gcttcttctt tctcgacagc
    18181 aaaaggaagt actttatttg gcaagaattc tccgcttaaa cgtcccgata gtacgacggg
    18241 attatggcag tagtaacaat aagtcgcagc agttgtcgca tcagtcacga tctctgcacc
    18301 acagttggga caaagaaaaa gatctatcgc tgcggtatta tctgcagatt cgtccgctgt
    18361 atctgaaaaa ccgcctgcct cgtcaaccgc tttgcgctcg gcttcattca tatcggcaag
    18421 ctgttcttgg gctgtaaaag taaaatcttc ggtaggtgaa ggttcttctt tgctttcttc
    18481 gccagccata cgcgcttctt tttgcttttg ctcatattgg ctgacttctt cttctgtata
    18541 gatattcagg cagtattcgc aatgaaattt ttggtctttg ggatcaaaag tcaacggacc
    18601 gccgcaatta ggacatttat gtgtaagaac atccatcagc tgcacacctt tctaaataaa
    18661 ttaattaacg gggattcctt taaacggttt accacagttt ggacagaatt tagggatgcc
    18721 gttggaaaga tccacgatct cattgcattc actgcatcgc atttgtagct taggctgaac
    18781 gttttctaca ggtttggcag ctccgcagtt ggaacagaat tttccggaat tttctgtccc
    18841 gcaaactgga catgtccaag tatccgcatt tccttgtgca gtttgttgat tttgtttttc
    18901 tgcttgttgt ttgatttgtt cttggttatt ttgagctgct tgagaaagat aagaaccatt
    18961 tgcattcatt cccataccta cacccataaa gccggtcatt gctcctgctt cattttttcc
    19021 ggctgcttcc ataccacgtg caatggaacc ttgcacgtat ccttcacgta cgctaggatc
    19081 acctagcatc gccccttcgt tacgcatatt gatcagtttc acagaatcat cggtgtaaga
    19141 aatgctggct acagccacag aaacaatctc catcccacgt aattcacgcc aagaatcatc
    19201 caatgcagta tccatgtatt tgcttaattc caaactctta gatggtacat aagaaatccg
    19261 ttgaccatct gcagacatct gattgattgc tgattgtagc gctgttagga attcagctaa
    19321 atactgctca ttgatatcat tgatttccac ttgtgttttg tttttaggga ttgcgtttgt
    19381 ataaaataaa atcgggtcaa cgacatgaat agaataagtg ccatgtgccc gtaagaataa
    19441 ttctgcgtta tagaaattgt caaagtagtt caacggcgcg cttgtaccga atttgattcc
    19501 ctttatttct tggagattga tataaaaaac ttgttgtttc tgcggtgtga cgccgccaaa
    19561 tttgaatcgg tcaaaagttt cagcaattgc ttctttcagt gttccattga acatggaagg
    19621 agctgcgtca tttttaatgg tgtaataacc ttcctcagcg gtataatcga tgatttttcc
    19681 accatcgacc aaaagcatca tcatgtttgg atagacatgg acgactgttc cgtctgttaa
    19741 aacatcttct gttcctttac gattggagcc acgtttgtca tctttgcgga ctttgacacc
    19801 ttttgtcatg accgttgtat cactcatatt gtctggttcg atgacttcta gccattgatc
    19861 tgccagaccg ccgccaacca tacttgttgc tgctttgata agacccataa aaaattcctc
    19921 ctctgattca gctagtgcca aacaattatt gtttatttat tataccatag gaagatgtga
    19981 aacttctcgg actagagacg gaattgaaat ggaaaattgc gtattgttta aatacctgaa
    20041 aaagccgaga aggatagtag tttttttacc taatatcacg tataataaga gatagtgaat
    20101 tttttaaaaa agggggatcc ttatggcata tcaagcactt tatcgagtct ggcgttcgca
    20161 gcgtttcgaa gacatcgttg gacaaaaagc tgtgacacag acactaaaaa atgctattgt
    20221 ttcccacaaa acctcacatg cctacttgtt tacaggaccc agaggaaccg gaaagacgag
    20281 tgcagcaaag attttcgcaa aagcaatcaa ctgtccgaac agtaaagacg gtgagccatg
    20341 caacgaatgc gaaatgtgtc gatcaattac tgctggtacg caagaagatg tgatcgaaat
    20401 cgatgctgcc agcaataacg gagtcgaaga aatccgattt atccgtgatc gggcaaatta
    20461 tgcgcctaca aaggcagcgt acaaagtgta cattattgat gaggtacata tgctttcaac
    20521 aggagctttc aatgccttgt tgaaaacatt ggaagagcca aaagaaagtg tcatattcat
    20581 cttagcaacg accgaacctc acaaaatacc agctacgatc atttcacgga ctcagcgatt
    20641 tgattttaaa cggatcaata cggcagatat tgtcgaacat cttgaattta tcttgaaaga
    20701 atcgactatc agctatgaac cagctgcatt gaatgtgatt gcccgttctg cagaaggcgg
    20761 gatgcgggat gcattgagta ttcttgatca ggcaatctcg tttagtgaag gaacaattac
    20821 tttagatgat gccatgcaag tgacaggtag cttaactgac gaaatgatgg acagttactt
    20881 gagtgcttgc gtgaaaaaag aagtaccaga agcattggaa acattgaacc aaattctcgc
    20941 agccggcaaa gaatcacgtc gctttctaga ggatatgtta caatactgcc gtgacttgct
    21001 gatgtatcag caagcaccta acctagttga ggaacaatcg agtacgatca gaagtacatt
    21061 tacagaattg gcacaaactg tttcagcgga tcagctgttt tcaatgataa agattttgag
    21121 cgatactcaa aatgaaattc gttttaccaa tagtgccgct atttatttgg aagtcgctac
    21181 agtcaaactt gcacagctac cgtctgcttc tgttccttca gcagatgtag catttgcaga
    21241 tgatcagata gtaaaacagc tacaacaaga gattaaggaa ctaagaaacg aaatcaagga
    21301 actacgcagt aatacaggaa ttgagaatac aaaagtacag ccggtacagc aaacaaatca
    21361 taaaaaacag acaagtacct atcgtgtacc gacggaacga gtatataaag ttctgcggga
    21421 agcgacaaga cagcatctga accaagtaaa agaagtatgg gaagacttgc tgatgagtct
    21481 atctgtcact cagcgagcaa tgcttaaagc aagcgaacca gttgcagctg gacctacagg
    21541 actagtgatt gcgtttgatt atgagattgt ttgtcaaaga gcagcaaatg acgaagaatt
    21601 gcagctttcg gtacacaaca acttaagccg aatgatcaaa gattatgcgc ctgatcctgt
    21661 ttatattaca agagaaagct ggccagaact tcgaagaaat tatttgacgc aggcacaaga
    21721 agagggaaca gaaaactctt ttgcttctga agactcagaa ggagaaatcg agttgcttcc
    21781 tcaagaacaa gaagtaccag aagaaacact tgtagtaaaa gcagaggaac tgtttggctc
    21841 cgaagctgtt acagtggtag atgattaata aaaaggagta gataattatg atgcgtggaa
    21901 tgggcaatat gcaaggcatg atgaaacaag tacaaaaaat gcaaaaagaa atggcagaag
    21961 cacaagagct gctaaataaa acagagttta caggtaaagc caccaatgaa ttggtcaaag
    22021 cggtttttac aggcgatcgt cgcatgaaag atatccaaat caatgaagaa gtcgttgatc
    22081 ctgatgatat cgagatgctt caggatcttg tcgtaatggc agtcaatgat gcgatcgcac
    22141 aaattgatgt ggaaactgag aaaaaattag ggaaatacgc aaaaggtttg ccaggatttt
    22201 agttttaaac tgaaggagta atgaatatgc aatatccaga accaattgcg aaactgatcg
    22261 acagctacat gaaacttcca ggaatcggtc agaaaacagc gacaagactc gccttttata
    22321 cgatcgatat gaaagatgaa gtagtaaatg aatttgctaa atctttgtta agtgtaaaac
    22381 gcgatttgca tttttgtagt atctgcggaa acatcacaga agaagatccc tgcgaaatat
    22441 gtagaaatcc ttcacgtgat cgaagcgtta tcctagtggt cgaagagccg aaagatgtaa
    22501 tggcaatgga aaaaatgcga gaatatcacg gactttatca tgttctccat ggtgtgttat
    22561 caccgatgga agggacaggt ccagaagaca tcaatatttc ttctctgttg cagcggctgc
    22621 atgatgcaga tgtaaaagaa gtgattatcg caacaaatgc aacaacagag ggagaagcaa
    22681 cagctatgta tctctcacgt ctgatcaaac ccgcaggtat caaagtgact cgtctagcac
    22741 atggtctgtc tgtaggctct gatatcgagt atgcagatga agttacttta ttgaaagctg
    22801 tcgaaggaag acgtgagtta taaatttcta attaagtgtt ttttcagata caatataaaa
    22861 gcagcacaag agatgggggc aacaatgtga acggactatt tattacaatc gaggggcctg
    22921 atggtgcagg aaaaaccagc atcttgaatg aactttaccc tcttttgaaa gaagtagcaa
    22981 aaacagaaat cattcaaaca agagaaccag gaggcattcc gattgctgaa gagatccgag
    23041 cagtgatcct tgatccaaaa aatgatcgga tggatgaacg tacggaagca ctgctttatg
    23101 cagcagcaag aagacaacat ctagtcgaaa aggttctgcc tgctctggca aaagggaaaa
    23161 tcgttttatg cgatagattt gtcgacagtt ctcttgctta tcaaggtgca ggccgacgca
    23221 tcggcgttac cgagattgct cggttgaatg agtttgctac agaaggtact acgccggatt
    23281 ttacccttta tcttgacgta gattcagaca ccggattaag aagaatcaag aaaaacagac
    23341 aaaatcaaat cgaccgttta gattcggaag gtttggaatt ccaccagcgt gtacgtcatg
    23401 cttacttaaa gctggcagaa gagaatccgg aaagaatcca caaagttgat gcaagaaaaa
    23461 gctttgaaga agtgctgcaa acaagttatc atacaattat tgaacagtat ccgcaatttt
    23521 ttgaaaacta ggaaggtgaa cgtttatgaa aattatttta gcgattatcc aagacaaaga
    23581 cagcaaccgt ttatcaaatg aattgattga tgcaaatatc cgtgccacaa aactatcatc
    23641 gacaggcggc ttccttaagg ctggaaacag tacgtttatc gtgggtattg aagatgaccg
    23701 tgtagaagaa gcattggaaa tcatcaaaaa aacgtgtgaa tcaagaaagc aatttgtatc
    23761 tacacctgtt acactggata tttcgatgga tgggggcgtc ccttatccag tagaagtaga
    23821 agtaggcggt gccacagtct tcgtcttacc tgttgaagga ttccatcaat tttaggagga
    23881 gctgagctat gaatcaagaa ataaacttgg ctcaaatgca accgatcgtg tatcagcagc
    23941 ttcaacggag ttttgagcat gggcgtatcg ctcatgctta tctttttgaa ggggagaaag
    24001 gaacaggaaa acatgaagta ggtatatggc ttgcacagca cctgttctgt acccaaatga
    24061 aagacaatct gccttgtgga aaatgcaaca attgtcagcg gatcgaaaag aaagaacatc
    24121 cagatgtttt ggttattgaa ccggaaggac aaaccatcaa agtcgatcag atcagacgtt
    24181 tgcagacgga attcagtcgc agcggttacg aatcaagaaa aaaagttttt ttgatcaaag
    24241 aagctgaaaa aatgaatagc agtgcggcaa acagtttgtt gaaattcttg gaagagcccc
    24301 ctggagattt tttagcggtg ttagaaacag atgcagtagg aagaattctc cctactattc
    24361 aatctcgttg tcaagttctg cattttcaag aactttcgaa agaagcactg atccatcgat
    24421 tgcaagaaga gcagattcca ttggaaaaag caaaactttt ggctttctta acaaacagtt
    24481 taggaaaagc agttgaaatc tctcaagatg aatggtttaa tgatgctaag gacttgattt
    24541 atcaatggtt cgtttacttg caaaagcaag atactcaagc ctttatctat gtccaaaaaa
    24601 aattggtaaa atcatttaaa gaaaaaacac aacagtttac aggattatct gtcttgatgt
    24661 tttattatca ggaagcacag cgtcaagcag tagcaaacgg cgaatatggc aaagtgaaac
    24721 agataaacca gataattgaa cggatattga tcgcagagca gaaactacgc agcaatgtca
    24781 gttttcaggc tgttgcggaa cagttcgttt tgcatacgat tttttagctt gccgcaaagg
    24841 atgatgatca aggaggatgg aaatggtaga agtagtaggt gtccgatata gagatgcagg
    24901 tcatatctat tattttgcac caggagactc tgaatatgtt tatagtgaca aggtattagt
    24961 cgaatctcag caatccttac atattgctac tgttgtcctt cctaaaaaag agattgatcc
    25021 caatgacctt cctgaagcta tccgtccgat cttgcataaa gcgtcacaag ctgaattaga
    25081 aaaagacaaa aaaaacaaaa aagatgctta tgatgcattg aaaatcgcaa aagaaaaagt
    25141 gcagttgcgt gagttggaaa tgaaaatggt caaagccgaa tacacatttg atcgaaataa
    25201 attgattttt tctttcacag cggacgggcg aattgacttt agagaattgg taaaagatct
    25261 ggccgctgta tttcgtactc gtattgagct tcgacaaatt ggtgtccgcg atgaagcaaa
    25321 gataataggc ggaattggtc catgtgggcg tccattatgc tgttcttctt ttttaggcga
    25381 tttcgtgcct gtatcaatca aaatggcaaa agatcaaagt ttatctttga atccaacaaa
    25441 aatttccggt ttatgcggac gcttgatgtg ctgtctgcaa tatgagagcg aagaatacga
    25501 gacagcgaaa aaagaactcc ctgactttgg aaaagtaatt gctacacctg atggtaaagg
    25561 gaaagtcgta gggttgaatc tgcttagccg tatcgttagt attcggctga ctggacggga
    25621 aaatcctgtc gaatatgaat gggatgaatt gaaagaattt atccaagtag gtgagatgaa
    25681 tggataagag atcattatac gacggattga atcaattaga atcagagttg agaaatacat
    25741 taacagaact tgttgaaatg aagcatgctt tgcatgagat cgtagaaaaa aatacaactt
    25801 tggagatgga aaatcaacgt ctgcgggaac acctgcggga attgaaccaa gttgcacaag
    25861 ctccagctga aaatgtgaag caggaacttt ctaagtctcg tatgaatctt gaaaaaattt
    25921 atgaagaagg attccatgtc tgctacgatt tatatggatc aagaagggac aatgacgagc
    25981 cttgtgcgtt ttgtctagaa gtgatctatc gcgaaagcgg tcgatgacca ataacaagag
    26041 gagactggag cggagaaata ctgctccagt ctttttatta aggagattgt gacagatgta
    26101 taatcaaaaa agtttcaagg gaaatccggt atatggggat ttatatcttg taccgacgcc
    26161 aattggaaat ttagaagata tgagctacag aagtgttcgt atgctgcaag aatccgatct
    26221 tatcgcaagt gaggatacgc gtaatacaca aaagttattg aatcattttg aaatccatac
    26281 accccaaaaa agtttacatg aacataatta taaagaacgt gtccctcaat tgattgcttt
    26341 gttaaaagaa ggaaaaacga ttgctcaagt cagtgacgca ggaatgcctt ccatcagcga
    26401 tcctggacat gagctagttt tagcctgcat aaaagaaggg atttctgtga tctctatccc
    26461 aggacctaca gctgggatga cggctttgat tgcttcaggg ctagtgcctc aaccattttt
    26521 attttatggc ttccttccac gtaagaaaaa agaacagaaa gaaacattga aaaagctaaa
    26581 agaacagaca gttacgctga ttttttatga gtcaccttat cggatcactg ctacattgac
    26641 gaatttctta gaaatttttg gaaatcgcca agtcgttttg tgtcgggaat tgacaaaggt
    26701 ccatgaagaa taccttagag gaagtacgga agagctactc gcttatatcg aagaacatcc
    26761 agtaaagggt gaatgttgtc tgcttgtaga agggaatttg ttcgaaatgc cagtgacgga
    26821 agttgatgaa gagttgggaa cgttaaagga acaagtagaa gcaaagatcg cttcaggcga
    26881 aaaaccaaat gctgctatca aagcagtagc gctgaaaaat gggctgaaaa aacaagaagt
    26941 ctaccgtcag taccatgaat tagactgaga tagtataagt tgtctataat gaaagactaa
    27001 tgaggaaatc agctactaac ttttcaaatc tcttgaacgc gaacgaatgt tcttgtataa
    27061 tgaataagag gtgaggatga tggagctgca atttccttta cataatgata catcaagaaa
    27121 aatcattcat attgatatgg atgctttttt cgcttcggtt gaagaacgag atcatcctga
    27181 gtttcgcgga catccattag taattgccag acaccccagt gacactggtg ggcgtggagt
    27241 agtgactaca gcaaattatg aagcaagaaa attcggaatt cattcagcaa tgagtgcaca
    27301 aaaagcgtat gagctttgtc cgcaagccat ctttaagcct ggcgaccatc ataaatacag
    27361 cgatatttcc aaacaagtac gggaagtatt ctatcgttat acagatattg tggaaccagt
    27421 tagtatcgat gaagcgtatc ttgatgtgac cgaaaataaa atcaattgca agtcagccat
    27481 caaaatcgcc cgaatgatcc aagcagatat ttgggagagt gtccagctaa catgttctgc
    27541 gggagtaagt tacaataagt ttttggccaa attagcatca gactatcaaa aacctagagg
    27601 aatcacggta gttgcccctc aagacgctgt gccattttta aaagctttgc caattgaaaa
    27661 atttcatggg gtagggaaga aaactgtacc tagaatgcat gagctaggga tttatacagg
    27721 aaaagaccta tatgaatgca cagaaatgat gttgattcga aattttggaa aaatgggcta
    27781 ttctctttat cgtaaagtca gaggaatcca tgattctcca gtaaacgtta caagagagcg
    27841 aaaatctgtg ggaaaagagc atacttatgg gcagccgttg caaacggaag aagcagtgct
    27901 gactcagttg cgccaactag ctgaaaaagt agaagaagca ctgagaagag tccaaaaaca
    27961 tgggaaaaca gtagttttga aggtcaggta cacggactat tctactgtga ccaaaagagt
    28021 gacattgcca gaatatatct ataaaaaaga agcactcttt tatcaagcaa gccttatatg
    28081 ggaggaaatc ttgggagtag aaaaaggaat ccgattgtta gggattactt tgacgaatct
    28141 ggacccgatg acttatgaaa acatcgtcct tccattatgg gaaaatcaag aaatataaaa
    28201 acagctttga gagttgaaac cggaaatccg ttttctctcc caaagctgtt tttatatcaa
    28261 gtcttgcttt ttgatttgtt cataggtttc tgttgcatcc gtacattttt cccaaatcac
    28321 aacttgattg gattctaaag atttttggac gtcaatgatc cgctggttgc tacttccgcg
    28381 aaattgtagt tttaggtcac gtttgcttaa ttcaaagcgt ccgtcaacaa ggatatcgat
    28441 ttgcgaaagg agttctaatt tatcttctga atcttgtagc aattcatcaa aggtatagcc
    28501 tgtccatgac cagatatctt ttgtcgtacc gaactctttt cggatacgtc gtacgacttg
    28561 cagacaaaca tctgtattca aaaaaggttc gccaccaagt aaagttaatc cttgcacgta
    28621 atcgttgcgc aagtcagcga tgatttgttc ttctaattca ggtgtgaatg gtttgccata
    28681 tcggaaattt tgtgcagctt tgttgaagca gccttcgcag gcaaataagc agccactaac
    28741 gtaaagactg ttgcggacac cttcaccatc gacaaaatta aacggtttgt agtcagcaat
    28801 atagttttgg ctgtagtctt ttgctaacca ttcttttggt tttggatttc tcataaaaaa
    28861 acttctttca tttaaggttc aaagatatag ctattgaaga taaaatctac tcgaccacat
    28921 aaataagaac aaactgacct aaatccattg ttcaagaaag cttgttctta ttttgataga
    28981 gggcgttcaa agatacaaag ccatcgaaag agggtggtga aaaaagactt gtcatagcct
    29041 cttattctga ataaacggtg ttcaaaagct tgcatctgca gtaataagcc caactaaacg
    29101 aaaaatatga ggaactattt ttgtttagct attcttatta cttgatgcag gacagctttt
    29161 tcacaacctc atttcatgtg tttcacacgt gaggaaattt ctttatggcg gccatgtacc
    29221 atcggacgag cttgcggatt tcctaaatag ccacaagtac gtttgactac atcacatgtt
    29281 tttggatcat gatttccaca ttctggacat tcgaaccctc gttctgtcgg tttgaaatca
    29341 ccttcgaaac cacattgata gcaatgatcg attggcgtat tcgtaccaag atacccgatt
    29401 ttgtcatatg caaaatccca tacagcttct aaagctttcg gattttgttg gagcataggg
    29461 tattcacagt agtggatgaa tccacctgaa caatattttg gataatcctt ctcaaattcc
    29521 aatttttcaa atggcgttgg gtttttacgc acatcatagt ggaaactgtt tgtataatat
    29581 tctttatctg tgatattttc gatgatgccg aatttttctg tatccaaacg gcagaaacgg
    29641 tcagttagac tttcacttgg agttgaatag acactgaaat gataaccata ttcatccccc
    29701 catgcatctg cattagcttt taattctttg acgatatcaa gtgtgaaagc ttttgcttct
    29761 gggtttgttt cccattcgcc accgaagaaa gctgaagcaa cttcatacaa tccaatgtag
    29821 cctaacgata cagtagctcg acggtttttg aataattcat tgacagaatc ggtacgtgaa
    29881 agacgtttcc cgaaagcacc atacatatat aaaattggcg catttgctgg aatggcttct
    29941 ttacaacgtt ctacacgata gagaagcgca tctttcatga tttctaagcg gtcagacagt
    30001 aactgccaga atttattctg atctcctttt gattcgatcg cgattcttgg caaattcaat
    30061 gtaacaacac ctaaattcat tcgtccgaca tttacttctt gaccattttc gtctttccac
    30121 ccttgcaaga atgaacgaca gcccataggt actttgaaac ttccagttaa ttcaacgatt
    30181 ttatcgtaat tcagaatatc aggatacatt cttttcgttg cacattccaa tgctagttgt
    30241 ttgatgtcgt aattaggatc ttcagggttt aagttcacac cttttttcaa agtgaagatc
    30301 agtttaggga agatagctgt ccgcttttca ctccctaatc cattgattcg aatctgtaaa
    30361 attgcttttt gaatttctct ttcaaaccag ttttctccta gtccaaatcc taatgaagtg
    30421 aaaggagttt gtccatttga agtaaataag gtattgattt catattccaa actttgcata
    30481 gcatcgaaga tatctttttt ggtttttgct tttgcatatt ctttttggcg ttctggcgaa
    30541 tcgatccatt cttccgcgtc ttttagatgt tttttatagt tcaattctgc aaaaggagca
    30601 agcaattcat ctgttcggtc ggcagaacag ccaccatatt gacttgacgc tacattggca
    30661 ataatctgtg agatttgtgc tgtggcggtc tggatagatt ttggcgattc gacttcggca
    30721 ttgccgattt tgaacccatt gttcagcatg cctttgaaat caatcaagca gcaattcgtc
    30781 atcggtgtat aaggatgata atccaaatca tggtaatgga tatcgccttt ttgatgcgca
    30841 tttgctatat gtggtggcaa cattttcagt ccgattgatt ttccaacgat cccggctgtc
    30901 agatctcgct gtgtattgaa aacattactg tctttatttg cgttttcgtt cacgacagtt
    30961 tggtccttgt tgattagctt ttcaatcgaa aagttgatat ctgttgcttt actgcgagca
    31021 aaatctcgtt tggtacgata attgatgtac tcttctgcta attcatattc gtttttttct
    31081 agtaatatat gttccacgat gttttgaatc tcatagattt tgacattttc agcaaaccgg
    31141 cttttgattt cttggacaac caagtctgca atcatttgaa ttttttcata agtaagtggt
    31201 gataatgagc cgtgaatttt cttttctgct ttgatcagtg cttcattgat cttttgttca
    31261 tcgaaatcaa catggcggcc atcgcgtttg atgactttca tctgggatgt ctctggctgc
    31321 tgagtaacga cagttttttc ttcataattt actttcatta tcttcaactc ctgctaaatt
    31381 gttcttgtct atcataaaac aaaatcgggg aaggagcaac taaatatcgg ctatatatag
    31441 tattcaatgt gctgtataat tggatttcta tactatatgt agtgtatatt ttattgtgaa
    31501 aaaaggtgaa aacttgtagc tggtggattt gttttttgca tatttaattt tgctgaataa
    31561 aataattgaa taaaattttt tattcagtcc aagtaaaagt gacaaaaaca taagagcaaa
    31621 ttattcgtag atatgctact atgcaaataa atagaaatga aaaatgaaag aggaggagaa
    31681 gaattggaaa agatgatcga agtgaaacat ctaagtaaaa gctacggcag caaactttct
    31741 cccgtcaaag ccttagataa tatctcattc acagtagaag aaggcgagtt tgttgggatt
    31801 atgggcccaa gtggtgcagg aaagacaacg ctgatgaata tcttgtccac gatcaatttg
    31861 cctacgatgg gcagtgtctc gatccaagga aaagaaatca caaaaatgaa aaacagtgag
    31921 ctcagtgact ttcgtcgaaa aaaactagga ttcatttttc aagagttcaa tttgatcgat
    31981 accctaaatg caaaagacaa tatcctattg cccctagcag ttgaacggat gactaaagag
    32041 gaaatggaaa agagagtaag acatgtagct caattgttga atatagaaga actgctcaaa
    32101 cggtatcccg atgaactttc tgtcggacag agacaacgaa ttgcagctgc tagagcactt
    32161 gttgttcagc cacaagtgat ttttgcagat gaaccaactg gctctttgga ctcgaagtcg
    32221 gctacagaat tgttgaacta cttgaagacc atgaatcaaa aagaaaaagc aacgatactg
    32281 ttagtcaccc atgatccata tacagcaagc tactgcgata gaattttatt tattaaagat
    32341 ggtgtgattt tttctgaagt tgtcagaaga gggacaagaa gagagttctt tgagaaagta
    32401 atagacatgc aggcgacgat tggcggagga ggaaaaatga atgctgtata aactagccgt
    32461 taaaagtttt tttcggcagt cacgaggcta tcttgtttat tttttcagtt tgactttatc
    32521 cgtaatgatc tattattcct tcagcgcaat gacctacgat caatctttag tcagaagagc
    32581 aagtcaagat acttcgatag atggtggatt gagttttggt ggatttatca ttactgttgt
    32641 tttgcttttt ttcgtattca gtgccaaccg atttttcttg aatagaaggc aaaaggaaat
    32701 aggcatctat cagctttttg gtatgaataa actgcagata tcaggtatat atgtgttaga
    32761 aatcatgata attggattgt tcgcctgtat ttctgggata ttactcggta ttattttttc
    32821 caaactcttt tcaatgattt tggttcgaat gatggatatg gatcttacta gtccattttt
    32881 tatctccatt ccatcagtag tagatacttt atttgctttt ttcatcatcc ttttagcagt
    32941 atctgtatat tcaatatgga aaatatggcg ctatccaatg attcgaagtt ttggagaaaa
    33001 agaacaagca gatagttcaa caatgcgctt caggacaagg caccgattac tcgcagtcat
    33061 cgggttacta cttttaacga gcggatattt tggagctagt cattttaggg aaatcacttc
    33121 atggatgatc agttatcatt atcttgatac attagttttc ttttttcctt ttttaatttt
    33181 tttcgtttgt gtggtcggta cttatttgtt tttctgttat acatttcggt tatttttgat
    33241 catattgagt aaatggaaga tttattacta tggtatcaat tttttgataa tgggtaacac
    33301 gcaagttcat ttgctcaaaa gttggcgtac aaattctctg attacagtca ttctcggaat
    33361 ttctttaatg acaattggcg gcacggctag tatctctact attttatcct accaggagaa
    33421 agtttcctcc ccgatggact atcagtttga tgttgagaca gagaaaaaaa tcaagccgat
    33481 tctagcagag gaagggcaga agataactaa agaaatcacc ttgcattata aagtcattgg
    33541 gagtatctat agtcaaaatc tcgaagaacc tatgtttcaa actgctaatc tgatcacgga
    33601 aacacaatat caagccttca gaaaagttaa tccagatttg ccgaacattt ctttgaaatc
    33661 acctggtcat actgttttgc ttgatcaaat gcaaactctt tttcggaata tttcattata
    33721 tggatctagt attggactgc cagataatca agaattgaag attcaacaaa tgcttccaag
    33781 tgtattaggt gacgaaacaa tggtatatct aagtcctgta ctgattgtag atgataccgt
    33841 ttttgaaaaa gcaaaaggtg tggattatca agtagtcaat gtagatgtat caggtggaaa
    33901 taatgaaaaa atagatgaac gactgagcaa tgacctgtcg ataaagtggc tcaatgctgt
    33961 ttattattct tatgatatcg taaatggaag tctacaagga gaaattagca caaagaaact
    34021 tccggatgac caaatgaagg aagcacaatt tagccaagaa agctctcgtt tgaatttctc
    34081 ttccagctat tcgaaattgc gtgcagttaa tcggcgaatc ggtatcaata tttttgtcac
    34141 actatttgtc gggatgatcg tgattattgc tactggtagt attttgacag tccggcaatt
    34201 agcagaagca gaggaagaaa aagaaaatta tcacctattg actaagctgg ggattccaca
    34261 aagaaggatc agacggatga tcttcgagca aaacgcactt accttctttc cacccatgat
    34321 attagggatc actcacgcag tatttgcaat caatgtcttc actcagtata taaaaactgc
    34381 cgattactgg ttggcttatc ttgtgagtgg cttattgatc cttatctatc ttttgcttta
    34441 tgtcattacg agtcagttat attgtcggat tatcgaggaa tgatatacgg aataagacaa
    34501 gataataaat agaactaaat tttgaatacc atttatttgg aataagaggt tgtgacacga
    34561 tttttgtcac aacctcttta ttttttatat tttttaaaag tacgagaaat tataaagaaa
    34621 aaagcagtga tttgatgtgc tatttttata aaagctatgt gacaaaactg ttagtaaaaa
    34681 aacggtttct gtaagctaga cacatgtttc tttttgtcaa aattagttac actttgtgtg
    34741 aggttatatg aggagggaat ccaatgaaca aatggcgttc taatccaaaa ttgaattatt
    34801 ggggaaaatt catcattcga acaatttttt atagtgcagt actgctgttc ctgatttatc
    34861 tgtatcacta taaaaatatt caaggaggaa cttttatcta taacgaattt taggaggaag
    34921 agtatggaaa tcaaaacgat tattgaagca atcgatgatt ggggaataaa tgaacctgat
    34981 cgagttgctt atcaggcgga tgagacgcat acttttggtg aattgaaaca agcatcagac
    35041 gcacttgctt attatttaga aaaaaaggta gaaggcgatg gaccaattgt cgtttttggc
    35101 aatttggagt ttgaaatgat tgtctcattt ctaggggttg tcaaatctgg ccatgcctat
    35161 ttgccgattg aagagcatac acccaaggag cgtatcctat cgatctttcg ggtggctaaa
    35221 ccatctatgg tcatcagtat cggggactgg atagaagata ttccttcggt tcctgtcata
    35281 acaaaaaaag aatttcaaga aatcaagaag ataccagtag gattttatcc cagaaatagc
    35341 gtaaaaggta cagaaaattt ttatattatt tttacttctg gtactactgg agaaccaaaa
    35401 ggcgtacaaa tcagtcatga taatctagtc agctttgttc aatggacgat ggaagacttt
    35461 gggatcaagc ctggtatgca tttcttagcc caagcgccat tttcttttga tttatcggta
    35521 ttttctattt atcctgcatt agtttctggc ggaatgctga agccgttaaa taaagcagtt
    35581 gttcaagact ttcgtcaatt attcgcgaca ttgccagcct tgaagttgaa tgtgtgggtt
    35641 tctactccat catttatgga tatttgcttg atggaaccta cattcaatgg agaaaatgtg
    35701 ccggaattgg acatgttttt attttgcgga gaagaattga cgaaaaaaac tgcagaaagt
    35761 ctacttgatc gattcccaaa tgcacggata tataatactt acggtccaac agaagcaact
    35821 gtagctattt caagtattca gattgaccag catgtactag atagttatga ccgactaccg
    35881 attggctacg taaaaaaaga cacgaaagtt tctattgtcc aagaaggtaa acctgtttca
    35941 aaaggagaaa cgggtgaaat cattattgca ggaccaagcg tatcaaaagg ttacctgaac
    36001 aatcccgaaa agacagctgc tgcgttcttt tgtcaaaatg acttagcaag ttaccataca
    36061 ggggatgcag gtagactaga tgaatatggg cttttatttt atgaaggacg tatggatcag
    36121 caggtcaaat tacatggata ccggattgaa ctcggggata tcgaacatta tctgctccaa
    36181 gacaaccgaa tcaaacaagc tgtcgtcgta ccaaaatacc aaggaacaaa agtacagcag
    36241 ctggttgctt ttgtcgtatt agaaaacaaa acgaaacagc cggattttca gttgactaaa
    36301 tctatcaaag aacaattact agaagttgta atggattata tgattcctca gaagttccat
    36361 tatgtcgatc tgctgcctca gacagttaat ggaaaaatcg atcgaaaaaa attaacagct
    36421 gaggtgaatc ctgaatgatg ttacctcata tgatccctta tgcagagccg ttttattttt
    36481 ttcttttagc cattgcgctt gtaccgatcg ttctatcttt attgatatgg gaaaaaagat
    36541 taccagttta tcaatcagca gtgacacttt tctttttatt tgtcagcttt ggaggtaatt
    36601 attggcaaca gggagcggcg ctgattgggt atgttttgtg gcagacgata cttgtatggg
    36661 gctattttgt ttatcggcaa aggaaaaatc agacaggatg gttttttgcc gccgttattt
    36721 tagcgataat tccactgttt ttaacgaaag tgactccttt ttttgaacat ggaaaagcat
    36781 cgttacttgg ttttttagga atctcttatt taacctttaa atctgtacaa atgatcatgg
    36841 aaataagaga tggcatgatc aaaacatata agccatttcg ttatatccag tttctgctgt
    36901 tctttccaac aatctcttct ggaccaatcg atcgctatag gagatttgaa aaagatcagc
    36961 tccatccgcc tgttcgtgat aaatatgttg atcttttggg aaaaggcgtc caaaatattt
    37021 ttgtcggttt tttatataaa ttcattatcg gttattattt tggtcaagta ctgcttcctg
    37081 tagtgggacg cattgcctta cagcatggtg gtatttcatg ggcattagta ggttatatgt
    37141 acgtgtacag tatgtatttg ttttttgatt ttgctggcta tagcttattt gcagtcggta
    37201 caagctacat gatgggatat cagacaccaa tcaatttcaa taaacctttt ttatcatgga
    37261 atatcaaaga attctggaat cgttggcata tgacgctgtc cttttggttc cgtgattatg
    37321 tatatatgcg attgatgttc ttcatgatga agaaaaaatt ttttaaaagc aagatcgtaa
    37381 tgtcaaatat cggttatttt gctttgtttc ttctaatggg tatatggcat ggattgacgt
    37441 ggtactacat cgtatatgga ctgtatcatg cttgtctgat ctgtctgaca gatgcatgga
    37501 tccgatttaa gaagaagcat aaagagcagt tgccttctaa caaatttacg catggcttag
    37561 ccgtattttt gacatttcaa gcagtatgtt ttagcttcct gattttttca ggatttttag
    37621 ataaactttt ttttagctaa cgaatagtga catattaatt tatataacaa aggagaaaag
    37681 gaaaatggaa gaacaaattt tatcaatctt agaagaaata acaggaacag atgaagtaag
    37741 aaaaaatcgt gatattgatc tatttgatga agggttgctt gattctttag catctgttca
    37801 attattagtc gagctagacg gagagctgga tatccaagtc cctgtatctg aattcgagcg
    37861 agaggattgg agcacaccga ataaaatcat tcaacaagca actgcattga agggttgagt
    37921 atgaaaaaga aactttttgc tattttcggc ccggttgttt tagctgttgg cttactgttt
    37981 gtgtttttta cctcctccta tcaagtagat atctctaatc cagaaacgat tagacgtgcc
    38041 tcttcttcca tgtcagtgaa cgtgttgaaa ggagatgcga taaaaaatta tgcattatct
    38101 gaaaaacaat atattccttt ttttggctca agtgaattaa gcagaatcag tccatttcat
    38161 ccgtctgttc tggcagaaaa ataccagcga aactatcgtc catttttgct gggagcaccc
    38221 gggacacaat cgttaagcca atatatgatg atgcgttctg caggagatgc tatgaaaaac
    38281 aagaaagtcg tctttattat ttctcctcag tggttcgtta aaaatggtgt aaaaactgat
    38341 tactttaata cgtattattc tgaacttcaa acatacgact ggttgttttc aatgaagaaa
    38401 gtaacgcctg ctgatcgcta tttagctaga agattattaa ctttctcaaa agtaaaagag
    38461 aatgatacgt tgacggcgat tctgcaaacg atcaaaaaag ggaagctacc tttacctgaa
    38521 tctttgaatc agctgcgcag ccaatggaac atgctgaaga gagaggatga agtattcagc
    38581 aatattgggt tgaaagatcg acagcaaaaa atcgatcatg agtcaaaacg attaccaaaa
    38641 caataccaag aaacagaatt atccatttta gcaaatcaaa ttggagaacg agaaacgacg
    38701 aataatccat tcgggttgaa aaacgatttt tatacgcatc gtatccgagc ccacgagcca
    38761 gagctcaaac agtcacaaaa aaattgggat tatcgttttt cgccagaatt ttctgatttt
    38821 cagctggtct tggatcaatt agcaaaaaac cataacgaag tattgttcat catcccaccg
    38881 gttaacgaga aatggagcga ttataccgga ctatctcaag aaatgttaca aggatttgcc
    38941 aaaaagatca aatttcaatt aaatagccaa ggattcaatc gaatagctga ttttgtcaat
    39001 caagcgggta ccaactattt tatggaagac acgatccatc taggctggaa aggctggttg
    39061 gctgcagatc aacagatcag accgttttta gaagaaaatc atattactgc tagtaagtat
    39121 catcttgacg atgctttttt tagcaaatct tggcaacatc aaataccaga taaactacaa
    39181 t
//
LOCUS       DAFBVQ010000020        38600 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.020, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000020 DAFBVQ010000000
VERSION     DAFBVQ010000020.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 38600)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 38600)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..38600
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.020"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(99..1229)
                     /locus_tag="LLC22_001211"
     CDS             complement(99..1229)
                     /locus_tag="LLC22_001211"
                     /EC_number="2.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-methyltetrahydropteroyltriglutamate--
                     homocysteine S-methyltransferase"
                     /protein_id="HBK5434501.1"
                     /translation="MSKNRPFTVDHVGSFLRPQSIKEARKKVQEGLLSKEELRAIEDQ
                     EIKKLVEDQKAVGIKGITDGEFRRGFWHLDFLEELNGIEGYVPETGYNQTFHGKAAPA
                     YNIRVVDKLSFNPNHPFLKDFAFLKEVVETDDTFVAKATIPSPTMILRQEILSNDGSS
                     KIKEIYPDLSDFYEDLSSTYKAAIHAFYEKGCRYLQFDDTNWAFLADQTKREALLQKG
                     IDPKEMAHICTEIINNALEDKPEDLTITTHICRGNHASSWLFSGGYEPIAEELFSTNY
                     DGFFLEYDSDRAGDFTPLRHWSNKESKVVLGLVTSKFPDLEDTEKIKERIKEAQQFVP
                     LENLSISPQCGFASTEEGNHLTEEEQWKKIQLLQQVAKEVWL"
     misc_binding    complement(1289..1516)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(1878..3080)
                     /locus_tag="LLC22_001212"
     CDS             complement(1878..3080)
                     /locus_tag="LLC22_001212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5434502.1"
                     /translation="MPKIKNIYQDKKTKKWFFRAYLGIDENGRKVQKTKRGYASQKDA
                     KIAYDKYMETHDFNKTIPNQLCSTNQMTFEEFYKDRFVKWYERQVKSQTYENAQFIFE
                     KRMQFFYHFRVRDITSHDIEDWLFELSQTESRNSRKKVNGETLSKSYINRIRGHLKIV
                     LDRAVKEGVIAKNPVEDVSSLPSENKKVEFWEHSEFQKVMNELKDDKIQTHHRKIVYE
                     MLFYTGIRIGELEALSWSNVDFEKNTITIEKTLIYNTKDDWYFSTPKTKCAYRTIGLG
                     KKLSLKLRQWYDLQKRIGNFEYVAQLDGTFTPPYSFANWLKEAAKKAGVKPIKLHALR
                     HSHVAFLIEQNIQPLSIQERLGHANIQITLGTYGHLYAKSDQQVVSAIDNVQEGAILS
                     KNDNLLPV"
     gene            complement(3140..3343)
                     /locus_tag="LLC22_001213"
     CDS             complement(3140..3343)
                     /locus_tag="LLC22_001213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 family protein"
                     /protein_id="HBK5434503.1"
                     /translation="METKCDFMVNRAILIEMGFKPSQAARMIKESKAYLARIEGIDFY
                     NNRQVGVVPSRVIEQLFHIQVAE"
     gene            complement(3485..4717)
                     /locus_tag="LLC22_001214"
                     /pseudo
     CDS             complement(3485..4717)
                     /locus_tag="LLC22_001214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173388.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
     gene            4880..5692
                     /locus_tag="LLC22_001215"
     CDS             4880..5692
                     /locus_tag="LLC22_001215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434504.1"
                     /translation="MEIDKQAVGNRIRQIRQELKLSMEKFGKLIGDLPRSTVNNWERG
                     INLPKTETLHQIAEIGHVTNEYLLYGDQENQYILEMLQKKAGKLDPKIEGLIVDEIKH
                     ADLVSEKEMDRMIEFFITNLIPPTEQDQFTFQCIDEKKQLYLGSTNFGKEAQLYLQHD
                     NQNHILHMMPFTFSNFSVDRILVYLANQKSYSYFGKHLPKELGEKAILLYSINQLTSD
                     VRIAPLVYSEETASYQYTEDNQYLLEQQYLYLPFVMEVEKERLLNAAYPSSK"
     gene            complement(6716..6913)
                     /locus_tag="LLC22_001216"
     CDS             complement(6716..6913)
                     /locus_tag="LLC22_001216"
                     /inference="COORDINATES: protein motif:HMM:NF016526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="accessory gene regulator B family protein"
                     /protein_id="HBK5434505.1"
                     /translation="MLLRFLFSFCCALYTLRIFTGGVHLNSNILCYFMSVVIVIVAYQ
                     CMFIFRNVDFIILGLMFEFFW"
     gene            complement(7059..7937)
                     /locus_tag="LLC22_001217"
     CDS             complement(7059..7937)
                     /locus_tag="LLC22_001217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5434506.1"
                     /translation="MIYGAIEAGGTKFVCAVGTEELTILERVSFPTTTPVETMKQVID
                     FFKPFKEQLAGIGVGCFGPIDIQCKSTSFGHITSTPKLAWQNFNFVGTLKQYFNIPIE
                     WTTDVNAACYGEYVAGSGKGLAGVAYFTVGTGIGGGALFNGTFVEGFSHPEMGHMLIK
                     RHPKDNFSGNCPFHQDCLEGMAAGPAIEKRLGVKGQNLLADDSFWQIEAFYLAQCAYN
                     TTLMFSPDRIIFGGGVMKQEHMKKKVQDKFVELINGYVEIPPIDSYIITPELGDNAGI
                     IGGLALARKAVRNKQP"
     gene            complement(7976..9094)
                     /locus_tag="LLC22_001218"
     CDS             complement(7976..9094)
                     /locus_tag="LLC22_001218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2961 domain-containing protein"
                     /protein_id="HBK5434507.1"
                     /translation="MSILKNITQFKKIQSRAITPENPTGEKGKAAMLPSELGPSRKGR
                     GAIPLTSGEETVIADITGTGIIRHMWMTIRDRTEFGSFVLRDLILRIYWDGSDSPAVE
                     SPLGDFFCNGFGERCEVNSLPIVVNPTGGFNSYFEMPFQTSAKITIENLHPKDMSSFF
                     YTINYALVDELEENSLYFHANWHRERITKLQEDYKLIDRLKGQGYYVGTYLALTCLER
                     YWWGEGEFKFYIDGDSEYPTVTSTGSEDYFGGAWAFHEYDEFGRPHAKNYSTAFLGYP
                     YQSNRDATRDRFETGKLNAVHAFGDDAMPRHGLYRWHLQDPICFTEDLSVTLQQIGND
                     DVRLFERQDDVASVAYWYSTEASGNTKRHFTDRERLPR"
     gene            complement(9091..11190)
                     /locus_tag="LLC22_001219"
     CDS             complement(9091..11190)
                     /locus_tag="LLC22_001219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase"
                     /protein_id="HBK5434508.1"
                     /translation="MTINEVIYSPKHPFFNAELNDGNVTTSNEYSYYRNIPDVKGLTF
                     DVSNQKTLANLDVCGTIQTLTFYRENLLTEEKPGVWVNKQLSQTNSLSLKVEVNGIVY
                     HLSESDHRIEVDVIQDCLPRYIHHYSTFKVIVVSFAPILANKRLSMLVQQVYIVNETH
                     ESLQVSVKDVPSYQEKYSDQQNVLISQKGNKDTIAQQEVASFAIAFVDPNAFEEVMTF
                     QESDIEKWLKETLNYFAQLFGQLSMPNDRVVHLYRRALYQSFSSFGMNRQGQVVGSNW
                     GSYPATNRIWNKDMYYASLPFTMFEPELCQKTVLWFDQYGVKFPGSKFTGGINHSLSN
                     SLSSALLASLYFEHTGDTKFFERCPQVLLNASRIIEDILAQRRSGEPMLFPSVWLSDA
                     FALGKYHTGSNLCLWKACIGLAEIFEALEQLSLSKRYKNIACKLKESICKQMTIDGPF
                     GEQFLEGIGDEEKTTYSVKHYQKPILEQGLIFLSDVIVDGKINLLMHDGEESDTTLMP
                     FYQFLDNKDHLYQNTMAFSASSFNPTYSEEIKGITWGLESGATFPGFITVLMSELHNP
                     QAFVTRLEELICLADLDGSWWWWPYRLEAQQGEVVRDFGCGKCGWASGLFVSLMISQY
                     FGLKFKKGVLQIDPVDNLTFSWKNLKFGQAFISIECTQSELSISNLSEKPLKISDTKK
                     ILHVEKGKTIHIQRRKR"
     gene            complement(11241..12062)
                     /locus_tag="LLC22_001220"
     CDS             complement(11241..12062)
                     /locus_tag="LLC22_001220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5434509.1"
                     /translation="MKLADGISKDEKKLVRKMFWRSMTMYASVNPVTMGGGGFAYSMM
                     PFINHFYKSEEDRAAALERHTQYFSTTIPCASFVMGIAASMEKENSEKAGFDVESINA
                     IKTSLMGPLAGIGDSLFWGVWRVVTAGLAINLANAGNILAPIIFLVMFNIPNYLMRYY
                     GGVLGYSLGSKYIEKLYANGLIEILTKAASILGLIMVGAMTISMVKFNTVLSFSMKGE
                     ELMNVQEILDSIFKGIVPLLVTLSCFKLLDKKVGVIKIIFGMVVLGILLSLLGIA"
     gene            complement(12059..12868)
                     /locus_tag="LLC22_001221"
     CDS             complement(12059..12868)
                     /locus_tag="LLC22_001221"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5434510.1"
                     /translation="MYDAFVVALAVFIGVAGHEMFGMSMLSRPIVVAPLAGALMGDLQ
                     TGLIVGASLEAIFMGVVNIGISSTAEPSLAAGLATAFAIKMGGNVDAIIPIVFPLAVL
                     GLQLMNMIFSFVCGPMAAKFFKFAKSGDQKGIINLHFFMWFVHYALYALIPFFAVLFG
                     ADVVKSVLDNIPEVIMNGLTVAGNLLPAVGMAMLLRMLWSKNIAVWFFFGAVVMAYLE
                     LPLIAIAAVGTIIAIVIAQRDLQLKNISVHAVQSDAAVNATLDQEEEDFFQ"
     gene            complement(12889..13383)
                     /locus_tag="LLC22_001222"
     CDS             complement(12889..13383)
                     /locus_tag="LLC22_001222"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5434511.1"
                     /translation="MIKAVRIDERLIHGQVAMTWTKSLNLTGLVVASDEAATNDIQKM
                     TLKMAAPSNVKVIIKTVDDAIHLLKDPRAKDMRLMVLVPNVKDAVKVAKAFPTEIELM
                     NVGNAGKMTPPSEDKKTLSKEVMLTTSEIQDLKELVELYPDTVFQPTPAMEKRSAISI
                     LSDF"
     gene            complement(13395..13883)
                     /locus_tag="LLC22_001223"
     CDS             complement(13395..13883)
                     /locus_tag="LLC22_001223"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5434512.1"
                     /translation="MFLKVGTGIAYIKVNRKKGINHMKKILIATHGHLASGFLSSIQL
                     LTGKVQEITVINAYVDECDFEQELNVFVNQVNEQDQIFVFTDLFGGSVNQKITKTFLE
                     KEIAVTILSGFNLPILLEIVLATKELTKEDIQELVNKCQQELKMTILDEVHVVNEEED
                     FF"
     gene            complement(13960..16656)
                     /locus_tag="LLC22_001224"
     CDS             complement(13960..16656)
                     /locus_tag="LLC22_001224"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5434513.1"
                     /translation="MEYKYRIDILQPIVYYAFRHIKLEEKMKKSAKDRVFDELIRLTG
                     NMSSVTAEKISKNLGISRQNASHYLTRLVEDKKVEKLPGKPVLWKPLDEYAVVDNTEQ
                     INEAFHSVVGHDGSLREVIQKCIAAVKYPPNGLSVLINGATGVGKSFLATKIFEYAIH
                     EQIIEKDAPFAILNCADYADNPELLSATLFGYKKGAFTGAEKDTDGLLATANNGYLFL
                     DEVHRLSKENQEKLFLFIDTGNYRPVGENVNWHSAKVRFIFATTEKGENYLLDTFDRR
                     IQISVMLPTFEDRPIRERLELIQLFFQNEADVLQKDIIVSREALSLMLSHPFSGNIGK
                     LKNIIKISCADVYSRTQEEPLTIGKNEILIQLNMLESEVESLPIASLLIKKNQKIKTD
                     RIKPFDYDSILEKITQLINEGNFNENFSSIKNEVQHLVHHIDKDSFLSMSRKLMIQMF
                     RKVWVSVLGKTYGLTTSGPVAEIISRSYVISPSYKTDLTGINRTLAANLPRTTYLCNQ
                     FLEHLPPLSEKDENFLRLLIVVTLSDYVDESIELKGLLLAHGDSTASSIQAVVNQLCG
                     NYVFEALDMPVESNVSEIVESTRNFVKRQVNTDSLVLIVDMGSLNQIYTQIKNDLKGE
                     LLLLNNLTTSIALDIGLKMTMNAPFKQIAEDAADKYSINVQYFEGFSQSSNIIISCMS
                     GLGISDKLKDVFRHHLSDESIEVFTKDYRELRELIDQNDETYFDKTKLVITTSDLPRS
                     FSIPNINVYDILDGDGAANLEHILSPEMKPAEFNRLIQELVKFFSLEGIADRLNFLNP
                     TIVMSEVETVISKYENYYHFTLNGRVKLNLYMHTALMMERLFLARTEKSEEPNYDLKP
                     DEDEFYYVSRSIFQSMEMKYNFKVNAYELSLLYELLGPYIQK"
     gene            complement(17084..18157)
                     /locus_tag="LLC22_001225"
     CDS             complement(17084..18157)
                     /locus_tag="LLC22_001225"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5434514.1"
                     /translation="MKKLQSLFLGILIIIAVLLLGVRQLEKTSGMSGAKVLTIYNWGD
                     YIDPSLITKFEKEYGYKVNYETFDSNEAMFTKIQQGGTNYDIAIPSEYMIQKMIKEKL
                     VLPLDHSKIKGLNNIDPRFLDLDFDPDNQYSIPYFWGTLGIVYNDKFFDANQIKHWDD
                     LWKPELKDSLMLIDGAREVMGLSLNSLGYSLNSKNMAQLTEAANKLNHLTPNVKAIVA
                     DEIKMYMINEEASVAVTFSGEAADMMWENEHLHYVIPPEGSNLWFDNIVMPKTVKNKE
                     GAYDFINFMLEPENAAQNAEYIGYSTPNEEAKALLPKDISSDEQFYPSDDTISHLEVY
                     KDLGSKYLGIYNDLFLEFKMYRR"
     gene            complement(18154..18981)
                     /locus_tag="LLC22_001226"
     CDS             complement(18154..18981)
                     /locus_tag="LLC22_001226"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434515.1"
                     /translation="MKKFKWSYLYLGIVFLFLYAPIFYLIFYSFNEGGTMNSFTGFTW
                     ENYEAVFEDTRLIIIVLNTFMLAFLSALIATIIGTFGAMGIYYTKKRRARTALLSMNN
                     ILLVSPDVIIGASFLIFFTLLGFGLGFQSVLLSHIAFSIPIVVLMVLPKLQEMNDSMV
                     DAARDLGANNFQVVKNIILPYLSPGIIAGYFMAFTYSLDDFAVTFFVTGNGFTTLSVE
                     IYSRARQGISLEINALSALVFLFSMILVIGYYFISKENRPKRLKKNRRVREGVARLR"
     gene            complement(18982..19788)
                     /locus_tag="LLC22_001227"
     CDS             complement(18982..19788)
                     /locus_tag="LLC22_001227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434516.1"
                     /translation="MKTMRRIYSVPYILWLGLFVIAPVLMIIYQSFFDMNGQFTLNNY
                     LSYFTSGTSLSMTINSVWYAFLITFFTLIISYPTAYFLTKLKHKQLWLMLIILPTWVN
                     LLLKAYAFIGIFSVHGSVNHFFDFIGIGPKQILFTDFSFLFVATYIEIPFMIMPIFNA
                     LEEMNPSLISASRDLGANSFETFRRVIFPLSLNGVKSGVQAVFIPSLSLFMLTRLIGG
                     NRVITLGTAIEQHFLVTQNWGMGSTIGVILIIAMFIVMLLTGEKKKGGRS"
     gene            complement(19800..20885)
                     /locus_tag="LLC22_001228"
     CDS             complement(19800..20885)
                     /locus_tag="LLC22_001228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356508.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434517.1"
                     /translation="MGKPIISFDQVVKRYDDETVLKKVSFEIEQGKFYTLLGPSGCGK
                     TTILRIIAGFTEATEGDIYFEGKRLNDLPANKRQVNTVFQDYALFPHMNVFDNVAFGL
                     KIKKMSKSDIEKKVKDALRMVQLPGYEKREISEMSGGQRQRVAIARAIVNEPKVLLLD
                     EPLSALDLKLRTDMQYELRDLQQRLGITFIFVTHDQEEALAMSDEIFVMNKGKIVQSG
                     TPVDIYDEPINHFVADFVGESNIVDGVMIEDNLVEFVGKQFECVDGGMRLNEPVEVVL
                     RPEDLTITTPDKGKLVVTVDTQLFRGVHYEIICYDEQQNEWMVHSTKKAKEGSKVGLA
                     FEPEDIHVMRFNESEEEFDARLDSYEE"
     gene            complement(20902..21444)
                     /locus_tag="LLC22_001229"
     CDS             complement(20902..21444)
                     /locus_tag="LLC22_001229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308415.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5434518.1"
                     /translation="MEIGEKLRNLRIQKNLTQEELGERTDLSKGYISQLERDLSSPSM
                     ETFFSILEVLGVTPEEFFHQEAANLQVVYSKEDHTVYFDEENGYELEWLVADSNEKEM
                     EPVLLTFEGAGEYKTFEPSLSETFIFVLEGELELSLGETVYVAKAGQSIYYQATKQHQ
                     LRNHLKKRTKVLIVATQSYL"
     gene            21702..22691
                     /locus_tag="LLC22_001230"
     CDS             21702..22691
                     /locus_tag="LLC22_001230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306123.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxidoreductase"
                     /protein_id="HBK5434519.1"
                     /translation="MNAFRSFQVIKEPVFHTAISDLPFTELAENEVLVKIAYSDVNYK
                     DALAMSESGQVIRTYPMTPGIDLSGTVVQSNNPRFSKEDLVLATGFGLGVTHPGGYSQ
                     YQKVPGDWLVPLPKNMTLRQAMILGTAGFTAMLCVNALIRQGMTSDKKVVVTGASGGV
                     GSTAIALLHKLGFQSIIAFSRKEESVTWLKSLGALQVVRPDEFLPETTKALGKQQIDY
                     VIDTVGGEQLSSLLPLISYNGAVALCGNAGGIKLNATVLPFILRNIQLIGIDSVNVPI
                     DQRLSLWQQMADLQIADELVVQEITLDQLPETASKLLAGTHQGRTLVNVGDHK"
     gene            22688..23425
                     /locus_tag="LLC22_001231"
     CDS             22688..23425
                     /locus_tag="LLC22_001231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenate--cysteine ligase"
                     /protein_id="HBK5434520.1"
                     /translation="MKILITAGGTTEKIDQVRAITNHSTGRLGQALADYLAANPDTTI
                     DYVTTKQALKPKRHSNITIYTIESALDLFLQLEELTKKEHYDAIIHSMAVSDFTPAFS
                     FSEEQLAKNLPTSSTQEELDNWFAENEQTDTTVSKISSNTEHLVLVLKKTPKIISYLR
                     EWQPKAKIIGFKLLVDVPKESLLAVAKNSLINNKTDFIFANDLTEIHGETHHGYLLSK
                     DGTVEEAQSKSEIAALITEKIRLEESK"
     gene            23422..23973
                     /gene="coaC"
                     /locus_tag="LLC22_001232"
     CDS             23422..23973
                     /gene="coaC"
                     /locus_tag="LLC22_001232"
                     /EC_number="4.1.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300740.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopantothenoylcysteine decarboxylase"
                     /protein_id="HBK5434521.1"
                     /translation="MKKILLGVTGSISAYKSADLTSQFVKLGAQVDVIMSKSSTHFIT
                     PLTLQSLSKRAVHTDVMQESNPQVINHIELAKQADLFLIAPATANIIGKLANGIADDL
                     LSTVAMALPVGTPKLIAPAMNTNMYQNPITQRNLETLRSVGYQEIEPRESLLACGDFG
                     KGALADIQTIIEQVMLTLNERNA"
     gene            23989..24621
                     /locus_tag="LLC22_001233"
     CDS             23989..24621
                     /locus_tag="LLC22_001233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268018.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5434522.1"
                     /translation="MKNTKNFTLTAMFLAILILLAVTPLGFIPIGPINATTMHIPVII
                     ASIVLGPRLGAFLGGTFGLISMIRSTVIQTPLSFVFSPFIPVIGTEHGSWKALLIAFI
                     PRILIGVVPYFVYKGLRKLMKQKADSVSLFLAGLSGSLTNTILVMNMIYFLFQQDYAK
                     VIGTNLNAVYSAILAVIFTSGIPEGIVAGLATAAVCNVLLRYFKHPSLTN"
     gene            24706..25353
                     /locus_tag="LLC22_001234"
     CDS             24706..25353
                     /locus_tag="LLC22_001234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5434523.1"
                     /translation="MKIFVVGANGQIGRHLIKDLAPSSHEIFAGVRDVASQTLVKKEN
                     VSYVSFDLTWSVEKMTEAFKGIDVLIFAAGSQGKNLLQVDLDGAIKTVIAAENAHVSR
                     YLMVSAVYADEPAKWPESMTDYYITKHYADEWLKRTNLDFVILQPVTLTNDEEVTSIQ
                     LTKPNEKASKTITRSTVAAVLAALVEETDISRTTLVLSEGSKELNTAFQEWAKEE"
     gene            25358..26341
                     /locus_tag="LLC22_001235"
                     /pseudo
     CDS             25358..26341
                     /locus_tag="LLC22_001235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373408.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-quinone oxidoreductase"
     gene            complement(26744..28258)
                     /locus_tag="LLC22_001236"
     CDS             complement(26744..28258)
                     /locus_tag="LLC22_001236"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavocytochrome c"
                     /protein_id="HBK5434524.1"
                     /translation="MKKLVAGLLTAVALLAMSACGADQKNTAQTSSSTKESAEVSSGA
                     SEQVYTDPKEMKESYDVVIIGAGGAGMAAAIEAKDAGLNPVILEKMPVAGGNTSKSSS
                     GMNASETKFQKEEGIKDSNDAFYEETLKGGGGTNDKEMLRYFVDHSADAVDWLDQNGI
                     KLDNLTITGGMSEKRTHRPSDGSAIGGYLVEGLLNNVHEREIPIFVNADVTDIKKNGE
                     TVNEVTVHVQGEEPKEVTGKAIVVTTGGFGASKEFIEKYRPDLADYITTNQEGSTGDG
                     ITMIEKLGGQTVDMDKIQIHPTVQQDEGVLIGEVVRGEGAILVDQEGKRFVNEMDTRD
                     KVSAAITALPEKSAYLIFDQGVRDRATAIEFYDQKGYVTTGKTMEELAEKIDLPKETL
                     AKTVDGWNTDVAEKKDAQFNRATAMEHDLSSPNYYAIKIAPGIHYTMGGVKINTNTEV
                     LDKENQPIRGLYAAGEVTGGLHGNNRIGGNSVAEIIIFGRQAGIQAARFASENE"
     gene            28396..29202
                     /locus_tag="LLC22_001237"
     CDS             28396..29202
                     /locus_tag="LLC22_001237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434525.1"
                     /translation="MNHLKTFFTNSTKTAGRITNGIYILLRIIVVIMLVDQVWNQHWG
                     NTMLLLLTLILFEIPYFLEKILKIQIPNMLEIILLSFIFSSTVLGELSDFYGYFSMWD
                     TFLHAFSGFLAGGVGFSLVYLLNKNTKTMNLTPLLLAVVSFCFSMTVGVMWEFVEFSA
                     DKLLQFDMQKDTIIQQINSVELSKDGNTVYHVPDITRTIIESQNADGKTDKTIIQNGY
                     LDVGIMDTMKDLFVNFIGAVVFSVFGYLYSRNDYQKFTFIKNFIPKKIKR"
     gene            complement(29377..29946)
                     /locus_tag="LLC22_001238"
     CDS             complement(29377..29946)
                     /locus_tag="LLC22_001238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434526.1"
                     /translation="MLDKTLPYAEIWMTRPLQQNVPITPLAEGFEFRFYQKEDESAWA
                     EIETSVGEFQTTDEALEYFQQNFAPYPEELERRMFFVETKKGEKVATCTAWRKKSREQ
                     VYPVFHWLAVKPDYQGKGLAKALTARVLQEFPTLHTDGPIYLHTQTWSHQAIALYKKM
                     GFTFIAENLDGTPNPDYEKVMQVLSKLDK"
     gene            complement(30029..32089)
                     /locus_tag="LLC22_001239"
     CDS             complement(30029..32089)
                     /locus_tag="LLC22_001239"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacterial Ig-like domain-containing protein"
                     /protein_id="HBK5434527.1"
                     /translation="MCSKRRSKQLNKHACRLDKERSCSEKHYVKFMMRTMLISLSVGV
                     YMHVPVQATTQTIKVVRTSVSETTDSPITITHTFTDANGKQLLPALTSYNKVSYPPTI
                     NHYWLIPNKTLWTSETGSSVPLSIFSDMTDPTKGDQLKQITDILNHALTDIKDGGSAQ
                     VSYVYEKDYSQFERKKIDVLAGTKVSISDLVERLKNADGTQGDMSKVISNNGNIVDTT
                     NTGTSTISLSYFDPIALKTMTASAVIHVRADQTAIKGKDLHLRTGESYAPKDLVEYVT
                     KSDGTSGNKEEIKMNGTVDTTTPGEYPVVLTYIDSKTSNVAETTAVVYVEASAASSTV
                     ITHFIDSQTNKELQAETHMSSVNRIPDLRLPAEFSDRVPNIDLSTYEQNGKVTSISDW
                     MQANGLDRKSHWSEILEVLHSELMNNRKQSGGEITFTYVYIPDNRSLEGHDLIVHPNE
                     KINKEELIQSATNSLGKPVPLKDVSVTINEVPLEDGYLTKQTGDFTIMYSYHDPYSLQ
                     ELHAQSLLHVLPLNKQIDQKEQKRQEESLSEKKQQMAHAVSPTGKVKQTRSLELARIS
                     RKISESNKTIRQEAHLAPQVSGLENEILEPKIKQQSEKEFVAKQSEDQKESDDQKETK
                     KKRLSTIDSTDEHLQPQVPLPSPGTPAPGGGIPSSALGDFMRGMAGTWVYANRNEFDA
                     DDWF"
     gene            complement(32366..33844)
                     /locus_tag="LLC22_001240"
     CDS             complement(32366..33844)
                     /locus_tag="LLC22_001240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434528.1"
                     /translation="MKLDYLIEEEDREKLLLARYLEFEKKNYVVLPKLYETLGLSKFK
                     TRNYIIELNKEFTEFKTKPEIQISEEAEIHVERLNLTDIKNLRRIYFQRSKIARLLTE
                     IVDSKVTIEKFAENHFLSISRAYVKRRELVSFLEQHQIKLKKNILVGEEINIRNVLFG
                     VYFGVFNGFSMPFRESVMNEAKSIVQYFEYLFNLKLSATKRIKFNLLTTISLLRAYGN
                     QPIGKRFFSDEYFKSSEGMKIIKDLSHISFLHIPKEQIIDEISYIMLFLITEEEFELD
                     GAFGLAEAHFHDIHMISQKMSVELIDQLPFSIEISEEERLYIRKELRMGMMHVNRKNW
                     IFDFEMTSFTSKKQLQFFFETYPIFSTAIQKVIQENKRYFLGKDERFMIRLFYDYLFL
                     LVGICPVSYFEAPIHVCIDFSQGSAYTDYIISQVKGFKNYNIVIESRITSRTNIYLSD
                     CLLEKFNKEQIIWKNPPTPDDWEYFGNTIIREKNRHLTEKIS"
     gene            complement(34142..35077)
                     /gene="murB"
                     /locus_tag="LLC22_001241"
     CDS             complement(34142..35077)
                     /gene="murB"
                     /locus_tag="LLC22_001241"
                     /EC_number="1.3.1.98"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287058.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramate dehydrogenase"
                     /protein_id="HBK5434529.1"
                     /translation="MNKEEIVESLATITILFDEPLMNYTFTKTGGPADVLAFPKKQEE
                     VKQIIDYCRIHDIPWMVLGNASNLIVQDGGIRGVVIMLTEMKQIHVKGTMVIAEAGAS
                     LIDTTYAALAESLTGFEFACGIPGSVGGAVYMNAGAYGGEIKDVFAEVDLLLEDGTLK
                     TLTKDEMVFSYRHSKVQELRAIVLEARFSLQTGDYEAIKARMDELTELRQSKQPLEYP
                     SCGSVFKRPVGHYTGQLIQQAGLQGLKWGGAQVSEKHAGFIVNIDHATATDYIELIAH
                     IQEVIKEKFDVSLETEVRIIGEKQAISETSRSLAN"
     gene            complement(35150..36070)
                     /locus_tag="LLC22_001242"
     CDS             complement(35150..36070)
                     /locus_tag="LLC22_001242"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5434530.1"
                     /translation="MKIGVIGVGNIAEKAYLPTYAKKQGTLDFYFATRNKETKERIQK
                     EYGFQHLYETIDELLEEKIEACMIHAATKVHYELAKKCLENGIHVYIDKPLSVHLNEV
                     RELQELADKNQIILMIGFNRRFAPMVEELKRIPDKRLIHLQKNRIAAKETTEFVLYDL
                     FLHLIDTAVYLLDEPILRTKYQIRETKEFLEYAILQLETQNQTAILTMDLASGANIEK
                     YQVTSKNGTYEVNDLTQLVIQDADGKKVKEFGDWTNTLVKRGFEPMVEAFFSQIRLGK
                     SETELLKQKEVVRSHELCEEVLKDHYRHQL"
     gene            36183..36935
                     /gene="xth"
                     /locus_tag="LLC22_001243"
     CDS             36183..36935
                     /gene="xth"
                     /locus_tag="LLC22_001243"
                     /EC_number="3.1.11.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291429.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exodeoxyribonuclease III"
                     /protein_id="HBK5434531.1"
                     /translation="MKFISWNVNGLRAIVNKNFLEVFHELDADFFCLQETKLQAGQID
                     LDLPGYYQYWNYAERKGYSGTAIFAKKPALNATYGMGIDIHDTEGRLITLEYSDFFLV
                     TCYTPNSQSELKRLDYRLEWEEAFYNYLENLKKQKPVIVCGDLNVAHQKIDLKNWKTN
                     QKNAGFTPEERAALSRLLDNGFIDTFRYFYPTQEGVYSWWNYRFNSRKNNAGWRIDYF
                     LTSKDLEPGLADAKIHTDIMGSDHCPVELDLK"
     gene            37799..38332
                     /locus_tag="LLC22_001244"
     CDS             37799..38332
                     /locus_tag="LLC22_001244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="exonuclease"
                     /protein_id="HBK5434532.1"
                     /translation="MNFVAMDFETANHQPYSACSLALVMVKNSQIVDEFYTLIQPETP
                     FFWRNVQIHGIHQEDVRNAPKFPEVWQTIQPYFQKNRLVVAHNAAFDTKVLAGCLDYY
                     HLEQPNYLSLCTVKSSRRLFPEFPNHRLNTVCENLNIQLDHHHDALEDSRACAEILLY
                     QEKKFGTDPLKKLVTIK"
BASE COUNT        11576 a         7961 c         6542 g        12521 t
ORIGIN      
        1 aaataaataa tataaaaggt aaataaaaaa gagtggattt ctccactcca tgaaaagccg
       61 actttttggg acgctttttt ttgccaagcc tcacattttt atagccaaac ttcttttgcg
      121 acttgctgca ataattggat tttcttccat tgttcttctt ctgttaaatg gtttccttct
      181 tctgttgaag caaacccaca ttgaggactg atacttagat tttccaatgg tacaaattgt
      241 tgtgcttctt ttattcgttc ttttattttc tccgtatctt ccaaatctgg aaacttagaa
      301 gtaactaatc ctaaaacaac tttactttct ttgttactcc aatgtcttaa aggagtaaaa
      361 tctcctgctc ggtcagaatc gtattccaaa aagaaaccat cataatttgt tgaaaacaac
      421 tcttctgcaa tgggttcata tccaccggaa aacagccaag aagaagcgtg attcccgcgg
      481 cagatatgtg ttgtgatcgt caaatcttct ggtttgtctt ccagtgcgtt attgataatc
      541 tctgtacaaa tatgggccat ttctttcgga tcaattcctt tttgaagaag tgcttctctt
      601 ttagtttgat cagctagaaa cgcccaattt gtatcatcga attgcaggta acggcaacct
      661 ttttcataaa aagcatgaat cgctgctttg taagtagagg acaagtcctc ataaaaatca
      721 gatagatcag gataaatctc cttgattttt gaagaaccat cattagatag gatctcttgt
      781 cgtaaaatca tcgtgggact agggatcgtt gcttttgcaa caaaagtatc atctgtttcc
      841 actacttctt tcagaaaagc aaaatctttt aaaaatgggt gatttggatt gaaagataat
      901 ttatctacta cccgaatatt ataagctggt gctgcttttc cgtggaatgt ttgattatat
      961 ccagtttctg gaacatagcc ttcgatacca tttagttctt ctaaaaaatc aagatgccaa
     1021 aatccacgcc gaaattcacc atctgtaatt cctttgatgc cgactgcttt ttggtcttcc
     1081 actaattttt ttatttcctg gtcttcgatt gcacgaagtt cttcttttga aagtaagcct
     1141 tcttgaactt tttttcttgc ttctttgatc gattgcgggc gtaagaaact tccgacatga
     1201 tctactgtaa atggtctatt tttgctcatt tcactcactc ttttctttgt tttttgtaaa
     1261 aaaaaatcct tttactagca aatactagta aaaggacgat tatactcgtg gtaccacctt
     1321 ttttcagaaa aaacattctt tctctcagcc tgacaataaa atcagtggtc ttggtaacga
     1381 aagactgttc gtttttgcct acctttcgac aaaaaatcct ctaaggccat tttcgacagt
     1441 caacttctag ctttttacac caaccaaagc ctctcttgaa ccattttctg tctactttcc
     1501 ttctcatcgg atactattag aataaaatta gaatagcatg tttgaaagaa aagtcaatag
     1561 ggaataagaa caaacaaaaa ctaatttgtt attcttagta atttgtttgt ggaatacaat
     1621 aaagcttttc taatatgata attgttcagt cgtcctttca tcttagatca cttccttaaa
     1681 atgatcatac ccgtttcaac cacataaaaa aggacttaat tttgaaaaat ttcccatcaa
     1741 aactaagtcc tttttattat agttatgcaa atttgcttat tttctcgcta tttccgatac
     1801 atcttgaaca ggagcaattc gactgaaaac actggtgcaa aagcatttat ttgtcttatg
     1861 gtagaaccgt ggaaaactca gactggtaat aaattgtcat tttttgaaag aatagcgccc
     1921 tcttgaacat tatcaatcgc acttaccact tgttgatctg actttgcata taagtgaccg
     1981 taagttccta aagtgatttg aatattcgca tggcccaatc gttcttgaat agatagcggt
     2041 tgaatattct gctcaattag aaatgcaaca tgagaatgtc gtagcgcgtg aagcttaatc
     2101 ggtttgacac ccgctttttt agcagcttct tttaaccagt tcgcaaaaga ataaggtggc
     2161 gtaaatgttc cgtccaactg agcaacatat tcaaaatttc caatacgttt ttgcaagtca
     2221 taccactgtc tgagttttaa ggaaagcttc ttccccaacc caatcgttcg ataagcacat
     2281 ttagttttgg gagtcgaaaa gtaccaatca tcttttgtat tataaatcaa tgtcttctca
     2341 atcgttatcg tgtttttctc aaaatctaca ttcgaccaag acaaagcttc aagttctcca
     2401 atccgaatgc cagtataaaa gagcatttca tacacaatct tccgatggtg ggtttgaatc
     2461 ttatcatcct tcaattcatt catcactttt tgaaactcac tgtgttccca aaactcaact
     2521 ttcttattct cagaaggaag cgaagaaaca tcttcaacgg gatttttagc aatcaccccc
     2581 tctttaacag cccgatccaa tacaattttt aggtgccctc gaatccgatt gatataagat
     2641 tttgataacg tttcgccatt aacttttttc cgtgaattac gtgactctgt ctggcttagt
     2701 tcaaataacc aatcctcaat atcgtgactt gtaatatctc gaacacgaaa atgatagaaa
     2761 aactgcatac gcttttcgaa aatgaattgc gcattctcat atgtttgact tttgacctgt
     2821 ctctcgtacc attttacaaa cctatccttg taaaactctt cgaaagtcat ttgattggta
     2881 gaacacagtt gattaggaat tgtcttgtta aaatcatgtg tttccatgta cttgtcataa
     2941 gcaattttgg catctttttg tgaagcataa cctcgtttag tcttctgaac ctttcttcca
     3001 ttttcatcta tacctagata cgctcggaag aaccattttt ttgtcttttt atcttggtaa
     3061 atatttttaa tttttggcat cgttccattc ctccctgtac ttgagaaaag ctactttaat
     3121 agtaccgcgc ttgtactgtt tattccgcaa cttgaatgtg aaaaagctgt tcaattactc
     3181 gggatggcac cacaccaact tggcgattat tataaaaatc aataccttca atccttgcaa
     3241 gatatgcctt gctctcttta atcattcgtg cagcttgact aggtttaaag cccatctcta
     3301 tcaaaattgc acgatttacc atgaaatcac attttgtttc cattctctca cctcctgatt
     3361 ctttactcct tttaaaataa tcctctttat aatctattgt ttctcattcg atggttgtgt
     3421 tatactcgtc ttgtcgaggc ggagtacgtt gcacaacttg ttgtgtaagc agtactttgc
     3481 ttttttagta gcttgttttc tcatttgata tactttgtaa ttttcgttca taatactcaa
     3541 cctcctcctg ataatactcc gggtctgcct tcatattttg gagaagtttg atctgtcttg
     3601 gattcatttc tccttgttca ataatcaaag gcaacaagga agaatgaaac gtttgatcga
     3661 cctgtgcaat aaaaactaat gatggtgaaa caccatgaat taaccaactc atagttttct
     3721 caaaactttg aggaattgta tctaaagaaa tggtgattgc gccataattg ctaataaagg
     3781 ctgcccattt ggcatcaact tttgcaccta gatcatttgg atcacggtca taaaaacaaa
     3841 ttgctccatt aagtaactca aagaacagtt tggttaaatc atgggttttt gaaataatct
     3901 ttgccaagct ttgcgctttc tcttttcgat accgtagttc aaagcgattc tttacttttg
     3961 cctcttctaa aggaattcct cgtcgcttcc gttgttcatg gtccttctga taaaagcaaa
     4021 aacgacactg actcttcttt gagcctaaat acaaggtctc accatttgat tcattgttta
     4081 tgatatccgt accgccatga gattcactca cttgaaaagt ggtccacaca tggcctagta
     4141 ttaccttatg cttaagttct ggaatgctga gactccccac aaaatcatct aaagtaaaat
     4201 caatccgtgt aaagttcccc tgataatcta ataccttacg aaaaaactgt tgccaatttg
     4261 tttttcgtgt ttttagccat cttgctaagt gtttacagcc ttgacctgaa aactccatca
     4321 cagttccttt aaccgcatcg tcaatggaat accgaatcgt gattacttga ttccacacgt
     4381 attggccaat atagcccttt ggcgcataat ccagttcctc aaaacgttca atgggcattt
     4441 caataatctc ttcaattagc tttaaatgtt gattcgagaa aaagtgaatg gttagataat
     4501 caatcaaaac acggttaact ggaacgacct cttcttgcaa actatccaac acaagattca
     4561 atttttcttc acttaattgt ctcgttcctt tttctacttt cgataataac tatctcgaaa
     4621 tccccacttt ttctgctaaa tatcgttgtg tccaccccct ttcttctcga gaaactcgaa
     4681 tggcttcacc gagatcatgt tgattaactt ggttcatcga caaacctcct tctgctattt
     4741 acttgtcaaa gaacctattg aacttatttt aagtacattt ttattgtacg cctgtattta
     4801 ttttaagtca atatgttttg acttttttta agtacacacg tatactaaat ttaagaactt
     4861 atcctgagga ggagttttca tggagataga caagcaagca gtcggcaatc gaattcggca
     4921 gattcgccaa gaattaaagt tgagtatgga gaaatttggc aaactaattg gtgatttacc
     4981 gcgaagtaca gtcaataact gggaacgtgg gatcaacctt ccaaaaaccg aaacccttca
     5041 ccaaatcgca gagataggtc atgtcaccaa tgaatatctt ttgtatggtg atcaagagaa
     5101 tcaatacatt ttagaaatgc tccaaaaaaa ggcaggtaag cttgatccta agattgaagg
     5161 tctcatagta gacgaaatca aacacgctga ccttgttagt gaaaaagaaa tggatcgaat
     5221 gattgaattt tttattacaa atctcattcc accaactgaa caagaccagt ttactttcca
     5281 atgtatcgat gaaaaaaagc agctttatct tggttcaact aattttggta aggaagccca
     5341 gctctatttg caacatgata atcaaaatca tattctgcac atgatgccct ttaccttctc
     5401 caactttagt gtggatcgca tactcgtcta tttagcaaat caaaaatcct attcctattt
     5461 tgggaaacat ttacccaagg aactaggtga gaaagccatc cttctatact caattaatca
     5521 attgaccagc gatgtgcgaa ttgccccgtt ggtctattca gaagaaaccg cttcttatca
     5581 gtacacagag gacaatcaat atctactaga acagcaatat ctttatctac cattcgtgat
     5641 ggaagtcgag aaagaacgcc tgttaaatgc agcgtatcca tcatcaaaat gaggtgacaa
     5701 aattgataag cacgtgacaa agaaaatact gctaggacac tccccaatgg gtagttgtca
     5761 cagtttcctg ttctttgtta gccccctgtt agaaccgggg gctttattcc tgcagtccgg
     5821 ctacgccttc ctgcaataga caaaactcca gatcgggtaa ttcgcttgtg gcgaaacccg
     5881 acctggagtt tgtctctgta ttttgaaccc taaaaattaa tcaaacagac tgatattctc
     5941 ataatcagcg cgaaataagc cattaagtac agttttccta cctatttttg ataacccgct
     6001 ggttagttaa tattcctttt ccgagagaga taaatgattg gttaaatcta tatacatctc
     6061 aacctttaaa aatgttttcg aaatacttca tcagtacatg tcatacaaat taccagtgca
     6121 ttctcaaatt ctagttcttt aattgatttc agttgaggag cagttacttt tggcggaaat
     6181 ttccattttt gtccaaacct cttcccccga tgaaatttct ttgttgcaat tattgcaatg
     6241 aaaaattttt gtttcaaaaa tatacataat tacttcctcc aataaaaact atctacctct
     6301 caaattattt ttctctaata agaaaaacag aaaaggtaat aagatacaac agtgatgatt
     6361 cctaataaag aaaagactac aataatattt ttctaactta tcgccttcaa agaaatagtt
     6421 tcttattttt cactaaaata aaaaatttat tgcaaaaaaa atagaagtga caaaattatc
     6481 aatcatttca aggtaatata actacctgag tttattatcg attaaaatgc taactacatt
     6541 tgcaagagaa gcgagagtta aaggtaaata tagaatttct acttttttag caatagaaat
     6601 aggaataaaa tatttaaaat gtatagaaac tttctttttt tttcttgcta tctttttata
     6661 atcacaactc tctataatag aattacgatt tattttatac ggctgaaaaa atctatcacc
     6721 aaaaaaattc aaacattaag ccaaggatta tgaagtcaac atttcgaaaa atgaacatac
     6781 attggtaagc aactataact attaccacag acataaagta acacaatata ttactattta
     6841 agtgtacgcc accagtgaat atcctcaagg tatacagcgc acaacaaaaa gaaaaaagga
     6901 aacgcagaag catttccttt cagtgattta atgaaaacaa cacgatttga cttagagcct
     6961 ttttatttga attcattttc gctttatcca acttcatttg atcatttgat tactcggtta
     7021 aatacttttg acatgagtat caatgaaaca ttcattaatt atggttgctt atttcttacc
     7081 gcttttctgg ccaatgctaa tccgccgatt attccggcat tatcacctaa ttcgggcgta
     7141 ataatgtagc tatcaattgg tggtatttca acatatccat ttataagctc aacaaattta
     7201 tcctgaactt ttttcttcat gtgttcttgt ttcattacac caccgccaaa aataattcta
     7261 tctggcgaaa acatcagtgt tgtattgtat gcacattggg caaggtaaaa ggcttcaatc
     7321 tgccaaaacg aatcgtcagc caataaattc tggcctttta cacccaaccg tttttcaatc
     7381 gctggtcctg ctgccatccc ctctaaacaa tcttggtgga agggacagtt tcctgaaaaa
     7441 ttgtcctttg gatgtcgctt gatcaacata tgccccattt ccggatgact gaacccttcc
     7501 acgaaagtcc cattgaacaa ggcaccacct ccgatacctg ttcccacagt gaagtatgca
     7561 acacctgcta accctttgcc agaaccagca acatattcac catagcaagc cgcattgaca
     7621 tctgttgtcc attcaatcgg aatattgaaa tattgcttta gcgttcctac aaaattgaaa
     7681 ttttgccaag caagttttgg tgttgatgtg atatgaccga aactcgttga tttgcattga
     7741 atatcaattg gaccaaagca gccgaccccg atgcctgcca attgttcctt aaaaggttta
     7801 aaaaaatcaa tgacctgctt cattgtttca actggagttg ttgtgggaaa actgactctt
     7861 tccaaaatcg ttaattcctc agtaccgact gcacagacaa atttagtccc tccagcttca
     7921 attgccccat atatcatcat aggttcctcc cttcgaatat gtgaaaaaca cttcattaac
     7981 gcggcaagcg ttctcgatca gtgaaatgac gtttagtatt tcctgaagct tctgttgaat
     8041 accagtaagc gacactagca acatcgtctt gccgctcaaa taagcgaaca tcatcgttgc
     8101 cgatttgttg taaagtgacc gataaatctt cggtaaaaca gatggggtct tgaagatgcc
     8161 aacgataaag accatgtcgt ggcattgcgt cgtcaccaaa ggcatgaacg gcattcaatt
     8221 ttcccgtttc aaaacgatct cttgtggcat ctctatttga ttggtaagga taccctaaaa
     8281 aggctgttga atagtttttc gcatgtggac gtccgaactc atcgtactca tgaaaggccc
     8341 acgccccgcc aaaataatct tctgaacctg ttgaggttac ggtcggatac tcactatccc
     8401 catcaatgta gaatttaaac tcgccttcgc cccaccaata acgttctagg caggtaagcg
     8461 caaggtaagt acccacgtaa tagccttgac cctttaatcg atcaattaac ttataatcct
     8521 cctgtaattt ggtaatgcgt tcccgatgcc aatttgcgtg aaaatatagg ctattttctt
     8581 ccaattcgtc caccaaagcg taatttatcg tataaaaaaa tgaggacata tccttcggat
     8641 gtaaattctc gatcgtaatt ttagcggatg tttggaaagg catttcgaaa taggaattaa
     8701 agccccctgt aggattaacc actatcggca acgagttcac ctcgcaacgc tctccaaacc
     8761 cattacaaaa gaaatcccct aaaggacttt caacagcagg gctatccgac ccatcccaat
     8821 aaattcttaa gattaaatca cgtaaaacaa aactgccaaa ttctgttcga tcacgaatcg
     8881 tcatccacat atgacgaatt attcccgttc cagtaatatc cgcaatcaca gtttcttcac
     8941 cagaagtcag cggaattgcg ccacgacctt tgcggcttgg tcctagctcg cttggcaaca
     9001 tcgcagcttt acctttctcg cctgttggat tttcgggagt gattgctcga ctctggattt
     9061 ttttaaattg ggtaatattt tttagtatac tcatcttttt ctcctttgaa tgtgaatcgt
     9121 ttttcccttt tctacgtgaa gaattttttt cgtatcactt attttcaatg gcttttctga
     9181 caaatttgaa atactcaact cggattgcgt acattcaatc gaaatgaagg cttgaccgaa
     9241 cttcaaattc ttccaagaaa acgttaaatt atcaacagga tcaatttgca atactccttt
     9301 tttgaatttc aatccgaaat attgactgat cattaggctg acaaaaagac ccgatgccca
     9361 gccgcatttg ccgcagccaa agtctcgcac gacttctcct tgttgagcct ctaagcgata
     9421 cggccaccac caccacgaac cgtctaaatc tgccaaacaa attagttctt ctaatcgggt
     9481 tacgaaagct tgagggttgt gcagctcgct cattaaaaca gtgataaagc caggaaaagt
     9541 ggcgccggat tctaatcccc aagtgatgcc tttgatttcc tcgctatagg ttggattgaa
     9601 agaactagca gaaaaggcca tggtgttctg atataaatga tctttattat ctaaaaattg
     9661 ataaaaaggc atcaacgtag tgtctgattc ttctccatca tgcatcaata aattaatttt
     9721 tccatccaca atcacatcac ttaaaaagat taacccttgc tcaagaatcg gtttttgata
     9781 gtgcttcact gaataggttg ttttctcctc atcaccgatt ccctccaaaa attgctcacc
     9841 aaaaggacca tcgatagtca tttgtttaca aattgattcc tttagtttac aggcaatgtt
     9901 tttgtatcgc ttgctaagac tcagttgttc tagggcttca aaaatttctg caagtccaat
     9961 acaggccttc caaagacaaa gattgctgcc ggtatgatac tttccaagtg caaaggcgtc
    10021 tgataaccaa acagatggaa aaagcattgg ttcccctgac cgacgttgag ctaatatgtc
    10081 ctcaataatt cttgaagcat tcagtagaac ctgcggacac cgctcaaaga attttgtatc
    10141 cccagtatgt tcaaaataaa gactagccag taacgcactg gataacgaat tactcagaga
    10201 atgattgata cctcctgtaa attttgaacc aggaaactta acgccatatt gatcaaacca
    10261 tagaaccgtt ttttgacata actccggttc aaacatggtg aatggcaatg atgcgtaata
    10321 catatcctta ttccaaattc gattagtagc aggatagctg ccccaattgc tgccgacgac
    10381 ctgtccctgt cgattcatac cgaaactaga aaagctttga taaagtgcac gacgatagag
    10441 atggacaact ctatcgtttg gcattgacag ctgcccaaat agctgagcaa aatagttcaa
    10501 tgtttccttc agccattttt cgatatcaga ttcctgaaaa gtcattactt cttcaaaagc
    10561 atttgggtcc acaaaagcaa tggcgaagct tgccacttcc tgttgtgcga tcgtgtcctt
    10621 atttcctttt tgagaaatca acacattttg ctgatccgaa tacttctctt gatacgaagg
    10681 cacatctttc actgaaactt gaaggctttc gtgtgtttca ttcacaatgt aaacctgttg
    10741 aacaagcata cttaaacgct tattagccag tatgggagca aaggatacta caatgacctt
    10801 aaacgtcgaa taatgatgaa tatatctagg caaacagtct tgaatcacat cgacttcaat
    10861 acgatgatcc gattctgaca aatggtagac aatcccgttt acttcaacct ttaaggataa
    10921 cgaattggtt tgagagagct gtttattgac ccaaacacct ggtttttcct cagttagtaa
    10981 attttctcga taaaaggtca acgtttgaat cgtcccgcaa acatcaaggt ttgctaatgt
    11041 cttttgatta cttacatcga aggtcaatcc ctttacatca ggaatattcc gatagtagct
    11101 gtattcgttt gaagtagtca catttccgtc gtttaactca gcattaaaaa atgggtgttt
    11161 gggtgaataa attacttcat taatagtcat cttttccctc cttgctaaaa aaactgcagc
    11221 ctagtagctg cagcttccta ctatgcgatt ccaagtaatg acaataaaat tcccaagacg
    11281 accattccaa aaataatttt gatgacgccg acttttttat ctagtaattt gaaacagctc
    11341 aatgttacca ataacggtac aattccttta aaaatactat cgaggatttc ttggacattc
    11401 attagttctt cgcccttcat tgaaaagctc aaaacggtat tgaatttgac catactgatc
    11461 gtcattgcac ctaccatgat cagacccaag atactagcag cttttgtcag aatttcaatt
    11521 aacccgttcg catacagctt ttcaatatat ttagagccta atgaatagcc taaaacgccg
    11581 ccatagtatc gcatcaagta attaggtata ttgaacataa ctaaaaagat aattggtgcc
    11641 aaaatatttc cggcattggc taagttgatc gctagtcccg cggtaacgac acgccaaact
    11701 ccccagaaca atgaatcgcc aattccagcc aatggtccca tcaaactcgt tttgatcgcg
    11761 ttgatacttt ccacgtcaaa accagctttt tcagaatttt ccttctccat cgatgccgca
    11821 atccccatga caaaggacgc gcaaggaatg gtcgtcgaaa aatactgtgt atgacgttcc
    11881 agcgccgcag ctcgatcttc ttcacttttg tagaaatgat taatgaaggg catcatagaa
    11941 taggcgaaac caccgccgcc catcgtcacc ggattcaccg aagcatacat agtcatcgag
    12001 cgccaaaaca tcttccgaac caattttttc tcatctttag aaattccatc agctaatttc
    12061 attgaaagaa atcctcctct tcttggtcaa gcgttgcatt tacagcagca tcgctttgaa
    12121 ctgcatgaac agatatattt tttagttgta gatctctttg ggctataaca attgcaataa
    12181 tcgttccaac tgcggcaatt gcaatcaatg gtaactcgag atacgccata acaacggccc
    12241 caaagaaaaa ccacacagca atatttttac tccaaagcat ccgtaacagc atcgccatcc
    12301 caactgccgg cagcagattt ccagcgactg ttaatccgtt catgatgacc tctggaatat
    12361 tatccaagac gcttttgaca acatctgctc caaataaaac ggcaaagaat ggaataagag
    12421 cataaagcgc atagtggaca aaccacataa agaagtgcag attgatgatt cctttttgat
    12481 caccagattt tgcaaatttg aaaaatttag cagccatcgg tccacataca aaagaaaaaa
    12541 tcatattcat taactgtaat cctaatactg ctagtggaaa gacaatggga ataatcgcat
    12601 ccacgtttcc tcccattttg attgcgaacg ctgtagccag cccagcagcc aaagaaggct
    12661 ccgccgtact agagattccg atattgacga cacccataaa gatggcttct agtgacgccc
    12721 cgacaatcaa ccccgtctgc aaatccccca tcaacgctcc tgctaacgga gcaacaacaa
    12781 tcggacgact cagcatggac atcccgaaca tttcatgtcc agcaactcca ataaaaacgg
    12841 ccaaagcgac tacaaatgca tcatacataa tttttctcct tcctttttct aaaaatcact
    12901 caaaatagag atagctgaac gtttttccat cgccggtgta ggctgaaaaa cggtatctgg
    12961 ataaagttca actaattctt ttaagtcttg aatttctgac gtcgttaaca tcacttcctt
    13021 tgataaggtt ttcttatctt ccgatggcgg tgtcattttc ccagcattcc ccacgttcat
    13081 taattcgatt tccgttggga aagctttcgc aacttttacc gcatctttga cattagggac
    13141 taaaaccatc aagcgcatgt ccttcgcccg cggatctttt aacaaatgaa tcgcgtcatc
    13201 aactgtttta ataatgactt tgacattcga tggtgcagcc atcttcaatg tcatcttttg
    13261 aatatcgttg gtagccgcct catcgcttgc tactactaac ccggttaaat ttagactctt
    13321 tgtccaagtc atcgctactt gtccatgaat taatcgttca tcaattcgca ctgctttaat
    13381 catttttctt cctcctaaaa aaaatcttcc tcttcattta ctacatgtac ctcatcaaga
    13441 atggtcatct ttaattcctg ttggcattta tttaccagtt cctgaatatc ctcctttgtt
    13501 aattccttgg ttgccaatac tatttcgagc agaattggca gattaaagcc agacaaaata
    13561 gttacagcaa tctctttctc caaaaaggtt ttggtaatct tctgattgac acttccgcca
    13621 aataaatcgg taaaaacaaa aatctgatcc tgctcgttca cctggtttac aaatacattc
    13681 aactcctgtt caaaatcaca ctcatccaca taagcattaa tcaccgtaat ctcttgaacc
    13741 ttccccgtca gtaattgaat actgctaaga aagcctgaag ctaagtgacc gtgagtcgct
    13801 attagaattt tcttcatatg gttaattcct ttctttctgt tcacttttat ataagcaatt
    13861 cctgtgccaa cttttaaaaa cattggttta atcacgttaa ttcacattaa aaaaagtgtc
    13921 taacctaaaa aaaacagatt agacactttt ttagacactt tatttttgaa tatacggtcc
    13981 taataattca tagagcagcg aaagctcata agcattgact ttaaaattat atttcatctc
    14041 cattgattga aaaatacttc tagaaacata ataaaattca tcttcatctg gtttcaaatc
    14101 ataattcggt tcttcagatt tttctgtccg agccaagaat aaacgttcca tcatcaatgc
    14161 cgtatgcata tagagattta gttttacacg gccatttaaa gtgaaatgat agtaattttc
    14221 atatttagaa atgactgttt ccacttcact catcacgatc gttgggttca gaaagttcaa
    14281 acggtccgca attccttcca acgaaaagaa ttttactagc tcctgaatca agcggttaaa
    14341 ttctgccggc ttcatttcag gactcaaaat atgctccaaa ttggctgctc catcaccgtc
    14401 taagatgtca taaacattaa tattaggaat tgaaaaggaa cgtggaagat ccgaagtcgt
    14461 gatgaccaat tttgtcttgt caaaataagt ttcatcattt tggtcgatta attcacgtag
    14521 ttctctgtag tccttcgtga aaacttcgat ggattcatcc gataaatgat gacgaaaaac
    14581 atctttcaat ttgtccgaaa tccccaaacc cgacatacag gaaatgataa tgttgctact
    14641 ttgagaaaag ccttcaaagt attgaacatt gattgaatac ttgtctgctg catcctccgc
    14701 aatctgttta aatggcgcat tcatcgtcat cttcaagcca atatcaagtg caatggaagt
    14761 cgtcaaatta ttcagaagaa gtaactcccc ttttaaatcg ttcttgatct gtgtgtaaat
    14821 ttgatttaaa gagcccatat ctacgatcag cactagacta tctgtattca cttgccgttt
    14881 cacgaaattc cttgtcgatt cgacaatctc tgacacatta ctctctactg gcatatccaa
    14941 cgcttcaaaa acataattgc cgcataattg attcactact gcttgaatgc tgctagccgt
    15001 actatctccg tgagcaagca acaggccctt cagctcgatg gattcatcta cataatcaga
    15061 taaagtcacg acaataagca gtcttagaaa gttctcgtcc ttttctgaga gcggtggtaa
    15121 atgctccaag aactgattac ataagtaagt cgtccgaggt agatttgcag ctaatgtacg
    15181 atttatcccg gttaagtctg tcttatagct tggggaaatg acataggatc tgctaataat
    15241 ttctgcaaca ggtccactcg tcgtcaatcc gtacgttttt cctaaaacgg atacccagac
    15301 ctttctaaac atctgaatca tcaattttct actcattgat aaaaaagaat ccttatcaat
    15361 gtgatgcacc aaatgctgta cttcattctt tatcgaagaa aaattttcat tgaaattacc
    15421 ttcatttatc agctgagtaa ttttttccaa aatcgaatca taatcaaacg gtttgattcg
    15481 atccgttttt atcttttgat ttttctttat caataaacta gcaatcggca agctttctac
    15541 ttcggattcc agcatattta actgaatcaa gatctcattt ttcccaatcg ttaatggttc
    15601 ttcttgtgtt cgactataca catccgcaca actgatttta atgatattct tcagcttacc
    15661 aatattccca ctaaagggat gagataacat taaagacaag gcttctcttg aaacaataat
    15721 atctttttgt aaaacatccg cttcattttg aaaaaataat tgaatcagct ctaatcgttc
    15781 tcgaatgggg cgatcttcaa aagttggcaa cataacacta atttgaatac gccgatcaaa
    15841 ggtgtctaat aaataatttt cacctttttc cgtcgtggcg aaaataaaac gaaccttagc
    15901 agaatgccaa tttacatttt caccgactgg acgatagttt ccagtatcaa taaatagaaa
    15961 gagcttttct tgattttctt tcgataggcg atggacctca tcgagaaaaa gatagccgtt
    16021 gttggccgtt gccaataaac catcggtatc cttttcagcc cccgtaaagg cccccttctt
    16081 gtatccaaac agtgttgccg aaagcagttc gggattgtcc gcataatcgg cacagtttaa
    16141 gatagcaaat ggtgcatctt tttcaataat ttgctcatgg atagcgtatt caaaaatttt
    16201 tgtggctaaa aaactttttc caacacccgt ggctccattt attaatacac tgagtccgtt
    16261 aggcggatat ttgacagcgg ctatacattt ttgaatgacc tctctcagac ttccgtcatg
    16321 accaactaca gaatgaaagg cttcgtttat ttgctccgta ttatctacaa ccgcatattc
    16381 atctaaaggc ttccacaaaa caggctttcc cggtaatttc tcgacctttt tatcttccac
    16441 taatctcgtc aaataatggc tggcattctg acgagagata cctagattct tcgaaatttt
    16501 ctcggcagtg acagaagaca tattccctgt tagtcgtatc agctcatcaa aaactcgatc
    16561 tttagcgctc tttttcattt tttcctccag tttaatgtgt ctaaaagcat aataaactat
    16621 cggctgcaat atgtctattc tatatttgta ttccaatttt tactttgaaa cacaaatagt
    16681 cgaatatttg cctcagatat ctgacaaaat aatttatcta ccaatttagt ttttatctaa
    16741 tatgattttt atgttttttc atagctacaa atattgaact ggattcatat attagtttta
    16801 ttaatagatt acagaagggt taagtatatt tgcatagttt ccaattactt tatccttctg
    16861 taactttttc aatcttagat ttactagccc gtctcgggcc ctattttaca atggttttgt
    16921 ccacttttct ctggtagaaa aacgtggtag aaaaaataaa ataacacaaa aaaagcggcg
    16981 tttcatccgc ttttggtaga agattggaaa actcagatag aaaaaggacg atttttagct
    17041 ctttagaacg ttgataagtc cccattctta ctgagttttg ccattatctc ctatacatct
    17101 tgaattctaa gaataggtca ttatagatgc ctaggtattt cgatcctaga tctttgtaga
    17161 cttcaagatg ggagatcgtg tcatcagatg gatagaattg ttcgtccgac gaaatgtctt
    17221 ttggcaataa cgcttttgct tcttcatttg gtgtagaata accaatatac tctgcatttt
    17281 gtgccgcatt ttccggttct agcataaagt tgatgaaatc ataggcacct tctttatttt
    17341 tcacggtttt tggcataacg atattatcaa accaaagatt ggatccttct ggtgggatca
    17401 cataatgtaa atgttcattt tcccacatca tatcggcagc ttcgccagaa aatgtcactg
    17461 ccacggaggc ttcttcattg atcatataca ttttgatctc atctgccacg attgctttga
    17521 catttggtgt taaatgattc aatttatttg ctgcttctgt cagctgtgcc atattcttac
    17581 tattcaaaga atagcctaaa ctattcaaag aaagccccat aacttctcgt gcaccgtcaa
    17641 tcagcatcaa actgtctttt aattccggct tccacaaatc atcccaatgc ttaatttgat
    17701 ttgcatcaaa gaatttatcg ttatatacga tccctaaagt tccccaaaaa tatggaatcg
    17761 aatactgatt atctggatca aaatccaagt ctaaaaatcg tggatcaata ttatttaatc
    17821 ctttgatctt cgaatgatct aatggaagta ctagtttttc tttgatcatt ttttggatca
    17881 tatattcact tggtatagcg atgtcgtagt ttgtcccacc ttgctggatt tttgtgaaca
    17941 tcgcttcatt agaatcaaat gtttcataat tcactttgta tccatattct ttttcaaatt
    18001 tcgtgatcaa actaggatcg atataatctc cccagttata gatggtaagt acctttgctc
    18061 cactcatgcc acttgttttt tcaagttgac gaacaccaag cagcagcacc gcaataatga
    18121 tgagaatacc taaaaacaga gattgtaatt ttttcatcgc agccgtgcca ccccctcgcg
    18181 tactcttctg tttttcttca gccgttttgg acggttttct ttactaataa agtagtatcc
    18241 aatgaccaat atcatggaga acaagaaaac taacgcactt agcgcattga tttctaaact
    18301 gattccttgt cttgcacgag aatagatctc tactgagagc gtcgtaaagc catttcctgt
    18361 gacgaaaaat gtaaccgcaa aatcatcaag agaataggta aatgccataa aatatccagc
    18421 tatgattcct ggagaaagat aaggcaaaat gatatttttg actacttgga aattattagc
    18481 accaaggtct ctagccgcat cgaccattga atcgttcatt tcctgcaatt ttggcaagac
    18541 catcaagacg acgattggaa tgctgaaagc aatatgggaa agcaatacac tctgaaaacc
    18601 taatccgaat cctagtagtg taaagaaaat caagaaacta gcaccgataa taacatcagg
    18661 agagactaat aagatgttat tcatgctcaa caacgctgtc cgtgcacgtc gttttttcgt
    18721 gtaatagatt cccatagccc caaatgtccc gatgatcgtg gcgatcaatg cagataagaa
    18781 agccagcatg aacgtattca atacgataat gatcaaacgt gtatcttcaa aaacagcttc
    18841 ataattttcc caagtaaatc ctgtaaagct gttcatcgtt cctccttcat tgaaggaata
    18901 aaaaatcaga tagaagatcg gtgcatataa gaataaaaag acgatcccta aataaagata
    18961 cgaccattta aattttttca tttatgagcg acctcctttt ttcttctcgc ctgtcaggag
    19021 catcacgatg aacatagcaa tgattaaaat cacaccgatt gtagaaccca tcccccagtt
    19081 ttgtgtaacc aagaaatgct gttcgatagc cgttcctaaa gtgatcaccc gatttccgcc
    19141 aatcagacga gtcagcatga ataaagaaag agaaggaata aatactgctt ggacaccact
    19201 tttcacacca tttaatgata acggaaaaat cactcgtcgg aaggtctcaa agctattcgc
    19261 gcctaaatct ctactagcac tgatcaaaga aggattcatc tcttccaatg cattgaaaat
    19321 tggcataatc ataaatggaa tctcgatata cgttgccacg aacagaaaac tgaagtctgt
    19381 gaataatatc tgtttcggcc cgatcccgat aaaatcaaag aaatgattca cgctgccgtg
    19441 cacactgaaa atcccaataa atgcgtaagc tttaagcagc agattcaccc atgtaggcaa
    19501 aataatcagc atcagccata attgcttgtg cttcagtttt gttaaaaaat aagcagtcgg
    19561 gtaactgatg atcagcgtga aaaacgtgat caaaaatgca taccatacag aattgatcgt
    19621 catagaaagc gatgtccccg acgtaaaata agatagataa ttattcagcg tgaattgccc
    19681 attcatatca aaaaaagatt gataaatgat cattaataca ggcgcgatca cgaataaacc
    19741 gagccacaaa atataaggga cggaatagat cctgcgcatt gttttcattc ttgtcccccc
    19801 tattcttcgt agctgtcaag acgtgcatcg aattcttctt cagactcgtt gaaacgcatg
    19861 acatggatat cttctggctc aaaggccaat cctactttgc ttccttcttt agcttttttc
    19921 gttgaatgga ccatccattc attttgctgt tcatcataac agatgatttc ataatggaca
    19981 ccacgaaaca gctgagtatc gaccgttacg actagttttc ctttatctgg tgtcgtgatc
    20041 gtcaaatcct ctgggcgtaa aacaacttca actggttcat ttagacgcat cccgccatcg
    20101 acacattcaa attgcttacc aacaaactca actagattat cttcgatcat tacaccgtcc
    20161 acgatattgc tctccccaac aaaatcagca acgaaatgat tgattggctc atcataaata
    20221 tctacgggtg taccactttg gacgattttc cctttattca tgacaaaaat ctcatcactc
    20281 attgccaacg cttcttcttg gtcatgagta acaaaaataa acgtgattcc taatcgttgt
    20341 tgcagatccc gcagttcata ctgcatatct gtacgtagtt tcaaatcaag cgccgataac
    20401 ggttcatcta atagcaatac tttcggttca tttacaattg ctcgtgcaat cgctacacgc
    20461 tgtctttgac caccagacat ttcactaatc tcccgttttt cgtatccagg aagctggacc
    20521 atacgcaaag catcttttac cttcttttcg atatctgatt tggacatttt cttgatcttc
    20581 aatccaaaag caacgttatc aaaaacattc atatgaggaa aaagtgcata atcttggaag
    20641 actgtattta cttgtcgctt attagctggc aaatcattca accgtttccc ttcaaaatag
    20701 atgtcccctt ctgtagcttc ggtgaatcca gctataatac gtaggatcgt tgttttacca
    20761 cagccggaag gaccaagcag tgtataaaat tttccttgtt cgatctcaaa acttactttt
    20821 tttaatactg tttcatcatc atagcgtttc actacttgat caaatgaaat gattggtttc
    20881 cccacgtttt taccccctat attacaaata tgattgcgtt gcaacaatca atacttttgt
    20941 tcgttttttg agatgattcc ttaattgatg ttgttttgtc gcttgataat agatcgactg
    21001 tcctgctttt gccacataga ccgtctctcc taagcttaac tctaattccc cttctaatac
    21061 aaaaataaac gtttcagata atgaaggttc aaacgtctta tattctcctg caccttcaaa
    21121 agtcagcaag acaggctcca tttctttttc attcgaatca gccacgagcc attccaattc
    21181 atacccgttt tcttcatcga aataaaccgt atgatcttct tttgaataaa ccacttgcag
    21241 attcgctgct tcttgatgaa aaaattcttc tggagtcaca cctaagactt caagaataga
    21301 aaagaatgtt tccattgatg gtgaacttaa atctcgttcc aactgggaaa tatacccttt
    21361 tgacaaatct gtgcgttcgc ctagttcttc ttgtgtcaaa ttcttttgga tgcgcaaatt
    21421 tcttaacttc tcaccaattt ccataatttc ctccgaatcg aagttttcta atagtaaact
    21481 tcctgtttac taccactcgt attagtatac gaaatttatt gaaaaaggca accctttgta
    21541 aaattttttt tgctgaatat ttctttatct tttggaataa attctagttg tttgattctt
    21601 tatttttcac ctaatttttg tctaaattta cggaagaaca agaataaaag agtaggcttt
    21661 atggtatgat aaaagaaaat tttaaaagga gtgtctcacg aatgaacgct tttcgatctt
    21721 ttcaggtaat aaaggaacct gttttccata cagcaatcag tgatctgcca tttactgagt
    21781 tggctgaaaa tgaagtcttg gtaaaaattg cctattctga tgtcaattat aaagatgcat
    21841 tggcaatgag cgagtctggt caggtgatac gaacatatcc gatgactcca gggattgatt
    21901 tatccggaac tgtcgtccaa agtaacaatc cacgtttttc aaaagaagat cttgtacttg
    21961 ctactggttt tgggcttggc gtcacccatc caggcggtta tagccaatat caaaaagtac
    22021 caggagactg gttagttcct ctaccaaaaa atatgacgct gcgtcaagcg atgatccttg
    22081 gtacagcagg gtttactgct atgttgtgtg tgaacgcttt aatccgtcaa ggtatgacct
    22141 ccgataaaaa agttgtcgtt actggtgctt ctggcggtgt aggcagtaca gcgatagccc
    22201 tgttacataa actaggattc cagtcaatca ttgccttttc cagaaaagaa gagtctgtca
    22261 catggctaaa aagtctaggt gctttgcaag tcgtacgacc tgatgaattt ctgccagaga
    22321 caacaaaagc tttaggaaaa cagcaaatcg actatgtcat cgacacagta ggtggcgagc
    22381 agctaagcag tcttcttcca ttgatctctt ataacggtgc agtagcttta tgtggcaatg
    22441 ctgggggaat caaactaaac gcgactgtct tgccttttat tctgcgaaac atccagttga
    22501 ttggaattga ttctgtcaat gtaccaatag atcaacgtct ttctttatgg caacagatgg
    22561 cggatttgca gattgcagat gaactggtcg tccaagagat tactctggat caattgcctg
    22621 aaacagcatc taaactactt gctggaacac accaaggaag aacactagta aatgtaggtg
    22681 accataaatg aagattctaa tcacagctgg aggaacgact gaaaaaatcg atcaagtacg
    22741 tgctattaca aatcattcga caggacgatt agggcaagca ttagctgatt atttagctgc
    22801 caatccggat accacaatcg attacgtgac tacgaaacaa gcactgaaac cgaaaagaca
    22861 ctccaatata acgatttata cgatcgaatc tgcactggac ttatttttac aattagaaga
    22921 actaacgaaa aaagaacact acgatgcgat tatccacagt atggcagtca gtgattttac
    22981 tcctgctttt agtttttcag aagaacagct ggcaaaaaac ctacccactt cttcaacgca
    23041 agaagaactg gacaattggt ttgcggaaaa tgaacagaca gataccactg tttcaaagat
    23101 ctcttctaac accgagcatc ttgtgctcgt tttgaagaaa acaccaaaaa tcatttctta
    23161 tctacgtgaa tggcagccaa aagcaaaaat cattggtttc aaactattag tagatgtacc
    23221 aaaggaatct cttctggcag tcgcaaaaaa tagtctgata aataacaaaa ctgattttat
    23281 tttcgcaaat gatttgacgg aaatccatgg cgagacacac cacggctatc tcttatctaa
    23341 agatggaaca gtggaagaag ctcaaagtaa atctgagatt gctgcattga ttactgagaa
    23401 aattagactg gaggaatcaa aatgaaaaag atcttactag gcgttactgg aagtatttct
    23461 gcttacaaaa gcgctgatct tacaagtcaa ttcgtcaaat taggtgccca ggtagatgtg
    23521 attatgtcta aaagcagcac acattttatc acgccattaa ccttgcaatc tctgtcgaag
    23581 cgcgcagtcc atacagacgt catgcaagaa tcaaatccgc aggtaatcaa tcatatcgaa
    23641 ctagcaaaac aagctgactt gtttctcatc gcgcctgcta cagcaaacat tatcggcaag
    23701 ctagcaaacg gcattgcaga cgatcttctt tcaacagtcg caatggcgct tccagtggga
    23761 acaccaaaat tgattgcccc tgccatgaac acgaatatgt atcaaaaccc gatcactcag
    23821 cgtaatctgg aaacattgag atctgtcggc tatcaggaaa ttgaaccaag agaatctctt
    23881 ttagcttgtg gagattttgg aaaaggtgcc ttagctgata ttcagacgat catcgaacag
    23941 gtcatgctga ctcttaatga aagaaatgct tagaaaaaag gagtacttat gaaaaataca
    24001 aaaaacttta cattaactgc gatgttttta gctattttga ttttattagc tgttacgcct
    24061 ttaggtttta tccctatcgg tccaatcaat gcaacaacca tgcatattcc tgtaatcatt
    24121 gcttcgatcg ttttaggacc aagactaggt gcttttcttg gcggtacatt tggactgatc
    24181 agcatgatcc gtagcacagt tatccaaaca cctttgtctt ttgtcttttc tccgtttatc
    24241 ccagtcatcg gaacagaaca tggaagctgg aaagccttgc tgatcgcgtt tattcctcgc
    24301 atcttgattg gggtggttcc ttatttcgtt tataaaggtc tgcgcaaact aatgaaacaa
    24361 aaagcagatt ccgtttcttt attcttagct ggactttccg gttcattgac caatacgatt
    24421 ttagtgatga atatgatcta ctttttattc cagcaagatt atgccaaagt catcggaaca
    24481 aatttaaatg ctgtttattc agctattcta gcggttattt ttacaagtgg tatacctgaa
    24541 ggaatcgtcg caggtcttgc gactgcagca gtatgcaatg tcttgttaag atacttcaag
    24601 cacccttctc ttactaactg atagtcatcg tagccgatct ctgatttttt tctcttttgg
    24661 tgttactatt gaatggaaag atttgacgtc gaaaggatga tccaaatgaa aatttttgtt
    24721 gtaggtgcaa acggacaaat tggccgacac ctgataaaag atttagctcc aagttcccat
    24781 gaaatttttg caggggtgag agatgttgct tcccaaacat tagtaaaaaa agagaatgtt
    24841 tcgtatgtct cttttgattt aacttggtcc gtggaaaaaa tgaccgaagc attcaaaggc
    24901 atcgatgtat tgatttttgc tgccggctct caaggaaaga atcttctgca agtagacttg
    24961 gatggcgcaa tcaaaacagt gatcgcagct gaaaatgcgc atgtctctcg ctatctgatg
    25021 gtcagtgctg tttatgcaga tgaaccagca aaatggcctg agtccatgac agattattat
    25081 attactaaac attatgcaga tgaatggctg aaacgaacta acttagattt tgtcattctt
    25141 caaccagtca cattgactaa cgatgaagaa gttacttcca ttcaattaac taagcctaat
    25201 gagaaggcat caaaaacgat cactcgctct acagttgctg ctgtacttgc cgctctagtg
    25261 gaagaaacgg atatttctcg tacgactcta gtactttctg aaggtagcaa agagttgaat
    25321 acagcattcc aagaatgggc aaaggaggaa tagatccatg cgtgccattt caatcaagca
    25381 tcctggttct gtagatgtat tagaacaaat tgaagtgcct gttcctaaac caaaacaagg
    25441 cgaattactg atcaaagtcc atacagcagc tgtcaatcga acagatatta tgaaaagaga
    25501 atcagtctct ttgaaacctc cctaccctat tttgggagtc gaagtagctg gagaggtagt
    25561 tgagaataaa agtgatatct ccacttttac tcctgggaca aaagtatacg gattagtcaa
    25621 tctaggtggt tatgccgaat atgctgtgat gcctgccgat cgtgcaatcc ttctccctga
    25681 tacgctagac tatgtttctg ctgctggaat ctcagaagtt tttttgactg cttatcaaac
    25741 actttactag cttggaaaat tacaagaagg cgaaactgtc ttgatccatg caggagcaag
    25801 tggtgtggga acagcagcga tccaattagc tagacagctt tctcacgcga aaatcatcgt
    25861 tactgcagga tcagaagaaa aactcgcctt ttgtaaagaa cttggtgcag atgaattgat
    25921 caactataaa aaacaagact ttcaagaaga ggtacgaaaa atcactgaag gtcggggagt
    25981 cgatgttatt ttggatttca tcggcgcttc ttactgggaa aagaatttag cttctatagc
    26041 cgttgatgga cgttgggtct tgattggtat gctaggtggg accatcgtgc ctgagataga
    26101 ccttggtgta ttgattggga aacgtgtcca actgcttggt acattattga cacctagaag
    26161 tgatcagtat aaagcagagc tcgcacaaac ttttatgcaa aaagctgggc cttttctaga
    26221 aaatggcaag attcggccaa tcattgaccg tacattccaa ttcagcgcag tcaaacaagc
    26281 gcatgaatat atggaagcaa acaaaaacat cggaaaaatc attttgaaga taactgaata
    26341 aaatcatgct gatcaaaaaa gaggctggga cagaagcgtt taactccaag aaataagaag
    26401 aaattcacga aaattgcttt tcaaattttt gtgaatttca gcttatttcc gaaggaattt
    26461 cttctgcttc cgccgtttat acgtgtttag agcgtgagac aaaagtgttc tttacttttg
    26521 tcccacgctc tttttccgaa taaacggtgt tcaaaagctt gcatctgcgg taataagtcc
    26581 aaccaagtta aaaacataag aagctgtttt tacttggctg ttcttattac ttgatgcagg
    26641 gcagcttttt cacaacctct tcactaaaca gtgttcaatc agctgaccct cggtattagc
    26701 tcaaaacgct gatttcacaa cctcttttta tttacgttct atttcattca ttttccgaag
    26761 caaatcgagc tgcttgtatg cccgcttgtc gcccaaaaat aatgatctcc gcaactgaat
    26821 ttccaccgat ccggttgttt ccatgtaagc cacctgtgac ttcaccagca gcatataacc
    26881 ccctaattgg ctggttttct ttatctaata cttcagtgtt cgtattgatt ttcacaccgc
    26941 ccatcgtgta atggattcct ggtgcgattt tgatcgcata ataattcgga gacgataagt
    27001 catgttccat ggctgtggca cggttgaatt gagcatcttt tttctccgca acatccgtat
    27061 tccatccatc aactgttttt gctagtgttt cttttggtaa atcgattttt tctgctaatt
    27121 cttccattgt ctttccagtt gtgacatatc ctttttggtc ataaaattca atagctgtgg
    27181 cacgatcacg cacgccttgg tcaaaaatca aataagctga tttttcaggc aatgctgtaa
    27241 ttgctgcaga tactttatcc cttgtatcca tttcattgac aaatcttttc ccctcttgat
    27301 cgaccaagat tgctccttct ccgcgaacaa cctcaccaat caagaccccc tcatcctgct
    27361 gcacagttgg atgaatttgt attttatcca tatcaacggt ttgtccacct aatttttcaa
    27421 tcatggtgat accatctcca gttgatcctt cttgatttgt cgtaatataa tcagctaaat
    27481 cgggacgata tttttcaata aattctttgc tggcaccaaa accgcctgtg gtaactacga
    27541 ttgcttttcc ggtgacctct tttggttctt ctccttgaac atgtacagtc acttcattga
    27601 ccgtttcccc atttttctta atgtctgtca catctgcgtt gacaaaaata gggatttccc
    27661 gctcatggac gttattcaat aacccctcca ctaagtatcc accaatagcc gagccatcag
    27721 acggacgatg tgtcctcttt tcactcatcc ctccagtgat cgttaagttg tccagtttga
    27781 taccgttttg atctagccaa tcgaccgcat cagcagagtg atcgacaaag tatcgaagca
    27841 tttctttatc attcgttcct ccaccacctt ttagcgtttc ttcatagaag gcatcattcg
    27901 agtctttgat tccttcttct ttttgaaatt ttgtttctga agcattcata ccgcttgatg
    27961 atttagatgt gtttcctccg gcaacaggca tcttttccaa aattactgga ttcaacccag
    28021 catcttttgc ttcgatagct gctgccatcc ctgcaccacc agctccaata atcacgacat
    28081 cataagattc tttcatttct tttggatctg tatatacttg ttcagaagcg cctgatgata
    28141 cttcggcaga ttccttcgta ctagaacttg tctgcgctgt atttttctga tctgcgccgc
    28201 atgcgctcat agcaagaagt gcaacggctg ttaataaacc agcaactaat tttttcattt
    28261 gtatccccct tttctcctta tactatatta agtgattttt ttcacaatat caactctgtt
    28321 tttctttaag tcatatagct ttggtaaaca cacgcttctt agtataatta aggatataca
    28381 tgaaggagtt attttatgaa tcatttgaaa acctttttta cgaacagtac aaaaactgca
    28441 ggtagaatca caaacggaat ctatatttta ttacgtatca tcgtcgttat tatgctagtg
    28501 gatcaggtct ggaaccaaca ctggggaaat acaatgcttt tattactgac attaatttta
    28561 tttgaaatcc cttattttct ggaaaagata ttaaagatac agattccaaa tatgctagaa
    28621 atcattttgt tatcttttat ttttagttca acagttttag gagagttaag tgatttttat
    28681 ggctattttt caatgtggga tacttttcta catgcattca gcggattttt agctgggggt
    28741 gtcggctttt cccttgttta tttgctcaat aaaaatacaa aaaccatgaa cttgactcct
    28801 ttattactag cagttgtttc cttctgtttt tcgatgacag ttggtgttat gtgggagttt
    28861 gtggaatttt cagcagataa attactgcaa ttcgatatgc aaaaagatac gatcatccag
    28921 caaatcaata gtgtggagtt aagtaaagac ggaaacactg tctatcatgt tccagatatc
    28981 actcggacaa tcattgaaag tcaaaatgca gatggtaaaa cagataaaac aatcatccaa
    29041 aatggttact tagacgtggg aatcatggat actatgaagg atttatttgt taattttatt
    29101 ggagcagttg ttttcagtgt atttggttac ctctatagtc gaaacgatta ccaaaaattt
    29161 acgttcatca agaattttat tcctaaaaaa atcaaacgat aaaacatgct aaaaaacaag
    29221 agaaggggca gtgacaatac ttttgtcact gccccttctt ttttgaatgt atggcatgcc
    29281 attagttatc cgatagtatt aactcaaaaa agtaagatat gaggaatgac tatttcgttt
    29341 tttatcccaa tactgaggac ttatttcacc atttcgttat ttatctaatt tacttaaaac
    29401 ctgcataact ttttcataat ctggattagg tgtgccgtct agattttcag caataaaagt
    29461 aaaacccatt tttttataaa gagcaatcgc ctgatggctc catgtctgtg tgtgaagata
    29521 gattggtccg tccgtatgga gggtaggaaa ttcttgcaag actctggcag tcaatgcttt
    29581 tgcgagccct tttccttggt aatctggttt cactgctaac caatgaaaaa ccggatacac
    29641 ttgctctctt gatttttttc gccaagcggt acaggttgct actttttctc ctttttttgt
    29701 ctctacaaaa aacatccttc tttcaagttc ttcaggataa ggagcaaagt tttgttgaaa
    29761 atactcaagt gcttcatctg tcgtttgaaa ttccccaacg gaagtctcaa tctccgccca
    29821 agcagattca tcttcttttt gataaaatcg aaattcaaaa ccttccgcta aaggcgtgat
    29881 tggaacattt tgttgaagtg gtcttgtcat ccagatttct gcgtaaggta acgttttatc
    29941 taacattttt ctatccctcc tcgtctccat tatgccaaat aacatatgac tcagctactt
    30001 atttgactat aacagataga gatataaatc agaaccagtc atctgcgtca aattcatttc
    30061 gattagcgta tacccatgtt cctgccatac ctcgcatgaa atctcctaaa gcagaagaag
    30121 gaatacctcc accaggtgcg ggtgttcccg gactaggaag tggtacttgc ggctgcagat
    30181 gctcatcggt ggaatcaata gttgacaagc gttttttctt cgtttccttc tggtcatctg
    30241 attccttctg atcttccgac tgtttagcaa caaattcttt ttctgattgt tgttttattt
    30301 taggctctaa aatttcattt tccaatccag aaacttgtgg ggccaaatga gcttcttgcc
    30361 ttatcgtttt attagattct gagatttttc tagatattct tgctaactct aggcttcttg
    30421 tttgttttac tttccctgtt ggagaaactg catgagccat ttgttgtttt ttttctgaca
    30481 agctttcttc ttgtcttttt tgttcttttt gatctatctg tttgtttaat ggtaaaacat
    30541 gtaatagtga ctgagcatgg agttcttgga gtgaatacgg gtcatgataa ctatacataa
    30601 tcgtaaaatc acctgtttgt ttggtcaaat aaccatcctc caatggtact tcattgattg
    30661 taaccgatac atcctttaac ggtacgggtt tacctaagga atttgttgct gattggatca
    30721 actcttcttt gtttattttt tcgtttggat gaacaataag atcatgacct tctaatgaac
    30781 gattgtctgg tatataaaca taagtaaagg taatttcccc tcctgattgc ttcctattat
    30841 tcatcagttc tgagtgaagt acttcaagga tctccgacca gtgacttttt ctgtctaatc
    30901 cgtttgcttg catccaatca gaaatagaag tgactttccc attttgttca taagtcgata
    30961 aatctatatt tggcactcga tcagaaaatt cagcaggtag gcgcaaatca ggaatacgat
    31021 ttacactact catatgtgtt tctgcttgaa gttctttatt tgtttgacta tctataaaat
    31081 gagtgatgac agtcgatgaa gcagcagatg cttctacata aactacagct gttgtttctg
    31141 ccacatttga tgttttcgag tctatataag ttaatacaac gggatattct cccggagttg
    31201 tagtatctac tgtcccgttc attttgattt cttctttatt tcctgaagtt ccatcgcttt
    31261 ttgttacata ttcaacaaga tctttagggg cgtaactctc tcctgttctt aagtgaagat
    31321 cttttccttt gatagctgtt tgatcagcac gaacatggat cacagcagat gcagtcattg
    31381 tttttaaagc aattggatca aaataggaca aggaaatagt agatgttcct gtattagtcg
    31441 tatccacgat attcccattg tttgaaatta ctttggacat atctccttgt gttccatctg
    31501 cgttcttcag cctttctacc agatcagata tcgaaacttt tgtccctgcc agaacatcga
    31561 ttttctttct ttcaaactgt gaataatctt tttcatatac ataagaaact tgtgcgcttc
    31621 caccgtcctt tatatctgtc aaagcatgat tcaaaatatc agtgatctgt tttaactgat
    31681 caccttttgt aggatcagtc atatcggaaa agatagaaag cggcacactg cttccggttt
    31741 ccgatgtcca taatgttttg ttaggaatta accagtagtg gtttatcgtt ggaggataac
    31801 tgactttatt ataggaagtc aatgcaggaa gtagctgttt tccatttgca tcagtgaaag
    31861 tatgagtaat agtgataggg gaatcagtgg tctcagaaac agaggtacgt acgaccttga
    31921 tggtttgtgt cgttgcctga acgggtacat gcatatagac acctacagat aaactgatca
    31981 gcatcgtgcg catcataaac ttaacgtagt gtttttcaga acacgaccgt tccttatcta
    32041 aacgacaagc gtgtttattt agttgttttg aacgtctttt tgaacacatt tattcttagt
    32101 cctccctact cttgtctaaa catgaagtag taattttcat aagatgattt cattatataa
    32161 ataaaatcaa aagaagatgg actattagga gagtattttt tttgattttt tattgtttca
    32221 agaaaatcgg aataataact tatgtacttt ttaattttgt taagtaatat atctagttat
    32281 atctagttat atctagttac cttttctttg aaaaaaacat aaatcagcta ataaatatgt
    32341 gagacaaagc tgccatccat aaatactagc tgattttttc agttaaatgt ctattttttt
    32401 ctctgatgat ggtatttcca aaatattccc agtcatctgg agtcggtgga tttttccaaa
    32461 ttatctgttc tttattaaat ttttcaagta aacaatcaga taaataaata ttcgtacgag
    32521 aagtgattcg actctcaatc acaatattgt aatttttaaa tcctttcact tgagaaataa
    32581 tgtaatcggt ataagcagat ccttgcgaaa aatcaataca gacatgaatc ggtgcttcaa
    32641 aatatgatac cggacaaata ccgaccaata aaaagagata atcataaaat aagcgaatca
    32701 tgaaacgttc atcttttccc aagaaatagc gtttattctc ttgtatgacc ttttggattg
    32761 ctgtactgaa tattggatac gtctcgaaga aaaactgtag ctgcttttta gacgtaaagc
    32821 tagtcatctc aaagtcgaat atccaatttt ttcgattgac atgcatcata cccatacgaa
    32881 gttcttttcg tatatatagt ctttcttctt cagagatttc aatcgaaaat ggtaattgat
    32941 caatcaattc cactgacatt ttttgactaa tcatgtggat atcatgaaaa tgagcttccg
    33001 caagtccaaa tgcgccatct aattcaaatt cttcttccgt gatcaaaaac aacatgatat
    33061 aagaaatctc atcaatgatc tgctctttag ggatatgaag aaaagaaata tgtgataaat
    33121 ccttgatgat cttcattcct tctgagctct taaagtattc atctgaaaag aaacgttttc
    33181 cgattggttg attcccatag gccctcaaca aactaatagt ggttagcaaa ttgaatttga
    33241 ttcgttttgt tgcagacagt tttaaattga acagatattc aaaatattgc acgatactct
    33301 ttgcttcatt catgacgctt tctctaaatg gcatagaaaa accattaaag accccgaaat
    33361 ataccccaaa taatacgttc cgtatgttta tttcttcccc aactaatatg tttttcttta
    33421 actttatttg atgctgttca agaaaagaga ctaattctct tctttttaca taggctcttg
    33481 atatgcttaa aaaatgattc tctgcaaatt tttcgatcgt tacttttgaa tccacgatct
    33541 ccgttaacag tcgagcaatt tttgatcgtt gaaagtagat tcttcttaaa tttttgatat
    33601 ccgtcaaatt cagacgttcg acatggatct ctgcttcttc tgaaatttgg atctctggct
    33661 ttgttttgaa ttcagtaaat tctttattta attctatgat ataatttctt gttttaaatt
    33721 tagacaaacc taatgtttca tataacttag gcagcactac ataattcttt ttctcaaatt
    33781 ctaaatatct agctagcagc agtttttctc tatcttcctc ttctataagg taatccaact
    33841 tcatatccta cacctcaaaa aatgcctcat accaattact tgatatgcag atgaaagttc
    33901 atcttttcac ctatactgat tttatgatgg attatgcttg ttttttcatc agttattctc
    33961 attttttatc ttttttttga gaatattgca aaaaatggaa aaatttatga ggaaatattc
    34021 tatatttttt gttttattgt gttaaaatgt acaagatttg cgccatttgc gtaaacaacc
    34081 acaaaaaaga gcaggacggc caccgtcctg ctcttttact tattttaagt tccattactt
    34141 attaattggc taaacttctg cttgtttctg atattgcttg tttttctcca atgatccgca
    34201 cttctgtttc taaagacaca tcaaattttt ctttgattac ttcttggatg tgcgcaatca
    34261 attcaatata atctgtcgct gtcgcatgat cgatattgac gatgaatcca gcatgttttt
    34321 cagagacttg tgcaccgccc catttcaggc cttgcaatcc tgcttgttgg atcagctgac
    34381 ctgtatagtg tcctactggg cgcttaaaga cacttccgca tgaagggtat tctaatggct
    34441 gttttgattg acgcaattcg gtcaactcat ccattcttgc tttgattgct tcataatccc
    34501 ctgtttgcaa actgaatcga gcttccaata cgatagcacg taattcttgg actttactgt
    34561 gacgataaga aaataccatt tcgtcttttg tcaaagtttt caatgttcca tcttcaagca
    34621 aaagatccac ttcagcaaaa acatctttga tctctccgcc atacgcacct gcattcatat
    34681 aaaccgctcc accgacactt cccgggatgc cgcaagcaaa ttcaaatcca gtcaatgatt
    34741 ctgccaaagc tgcataagtc gtatcaatca gtgaggcacc tgcttccgca atgaccatcg
    34801 ttcctttgac atgaatctgt ttcatttcag tcagcatgat gactacaccg cgaatcccgc
    34861 catcttgaac gatcagattg cttgcatttc ctaataccat ccaaggtata tcatggattc
    34921 ggcaataatc gatgatttgc tttacttctt cttgtttttt cgggaatgca aggacatcag
    34981 ctggtccacc tgttttcgta aacgtatagt tcatcaatgg ttcatcaaac aatatagtaa
    35041 tcgtggctaa gctttcaact atttcttctt tattcactga ggattttcct ttcttttctc
    35101 aaacgtcctc attattctat cacgcttaat acaatcttgc cagtcttgtt caaagttgat
    35161 gacggtagtg atctttaagc acttcctcac ataattcatg acttcttaca acttcttttt
    35221 gtttaagcaa ttctgtttcc gatttaccta aacggatctg agaaaagaag gcctctacca
    35281 ttggctcaaa cccgcgtttg actagcgtgt ttgtccagtc gccaaattct ttcacttttt
    35341 ttccatcagc atcttgaatg acaagctggg tcagatcgtt tacttcataa gtaccatttt
    35401 tacttgttac ttgatatttt tctatattag cgccacttgc taaatccatc gttaaaatag
    35461 ccgtttgatt ttgtgtttct aattgtaaaa tggcatattc caaaaattcc tttgtttctc
    35521 ttatctggta ttttgttctc aaaatgggtt catctaataa atacacagct gtatcaataa
    35581 gatgtaaaaa caaatcataa aggacgaact ctgtcgtttc ttttgccgct attcgatttt
    35641 tttgcaggtg gatcaaccgc ttatctggga tacgtttcaa ttcttctacc ataggagcaa
    35701 agcgccggtt gaaaccgatc atcaaaatta tttggttctt atcagctaat tcttgcaatt
    35761 cacgaacttc atttagatgg acactcagtg gtttgtcaat ataaacatgg ataccatttt
    35821 ctagacattt tttggctaat tcataatgta cttttgttgc tgcgtggatc atacatgctt
    35881 cgattttttc ttctaaaagc tcatcgatcg tttcatatag atgttggaac ccgtactctt
    35941 tttgaattct ttcttttgtt tctttatttc ttgttgcaaa ataaaaatca agtgttcctt
    36001 gttttttcgc ataagttggt aaatatgctt tttctgcgat attccctaca ccgattacac
    36061 caatcttcat ctactttcct cctggatcat ttagttactt tcatcttaca ccatttttta
    36121 ctaaaatgag gtacaatagt atcgcaaagg taaggaaatt aattcgaagg agtgtgcttt
    36181 tattgaaatt tatctcttgg aacgtaaacg ggcttcgtgc catcgtaaat aaaaattttt
    36241 tagaagtttt tcatgagtta gacgccgatt ttttctgtct gcaggaaacg aaactccaag
    36301 caggacaaat tgatttagat cttccaggtt attatcaata ttggaattac gcggaacgaa
    36361 aaggctattc cggcacagcg atttttgcta aaaaaccagc attgaatgcc acttacggaa
    36421 tgggtatcga tatccatgat acagaaggcc gtctgattac tttggaatat tccgatttct
    36481 ttcttgtaac ctgttacacg ccaaattctc aaagcgaatt aaaacgttta gattaccgat
    36541 tagaatggga agaagccttt tataattatt tggaaaatct aaaaaaacaa aaaccagtca
    36601 tcgtgtgtgg ggatctaaat gtcgctcatc aaaagattga tttgaaaaac tggaaaacga
    36661 atcaaaaaaa tgctggattc actccagaag aaagagcggc tctttctcga ctgttggata
    36721 acgggtttat cgatacattc cgttattttt atccaaccca ggaaggtgtc tactcttggt
    36781 ggaactaccg attcaattca aggaaaaaca atgctggttg gcggatcgat tactttttga
    36841 cgagcaaaga tttagagcca ggactagctg atgcaaagat ccatacggac attatgggca
    36901 gtgatcattg tccagtagaa ttagatttga aataaagagg ttgtgaaaaa gtcgtttagt
    36961 ttcgagtatt aagaaaaatt ttgtgaaaat ggctttccac attttgcata aatttggcat
    37021 aataccgaga aactggcttt tgaacactgt ttatcgagag attgtgaaaa agctgtcctg
    37081 catcaagtaa taagaacagc caaacaaaaa tagttcctca tatttttcgt ttggttgggc
    37141 ttattaccgc agatacaagc ttttgaacac cgtttattaa gaggttgtga aaaagctgca
    37201 ctgcatcaag taataagaac agccaaacaa aaatagttcc tcatattttt cgtttggttg
    37261 ggcttattac cgcagatgca agcttttgaa caccgtttat taagaggttg tgaaaaagct
    37321 gcactgcatc aagtaataag aacagccaaa caaaaatagt tcctcatatt tttcgtttgg
    37381 ttggacttat taccgcagat gcaagctttt gaacaccgtt tattgagaag ttgtgaaatc
    37441 agcgtcctga cctgagtatt agagaaacaa atggcaaaat agttcctcat attttgctat
    37501 tttttgagct aataccgagg gtcagctgat tgaacaccgt ttagtggaga agttgtgaaa
    37561 aagtcgccta ctttcgagtc gtaagaaatt tttttgaaaa tggttcctca caactttgca
    37621 taaatttgac ttaataccga gaagtcatga tccccatcta actccaaatc acaaggaatg
    37681 agttcaaaaa ctagcttttc tcaacaaata ttacataaaa aattctatgt tttttgttaa
    37741 atttatttgc ttttttcaaa agtatgttac agtaatttcc caaggaggtt ttacagaaat
    37801 gaattttgtt gccatggatt ttgaaactgc caatcatcag ccttatagtg cttgttctct
    37861 tgcgctagtc atggtaaaaa atagccagat cgttgatgaa ttctatacat tgatacagcc
    37921 tgagactcct tttttctggc gaaatgtcca aattcacgga atccatcaag aagacgtacg
    37981 caatgcgccg aaattcccag aagtctggca aactatccaa ccatattttc aaaaaaatcg
    38041 tttagtcgtt gcacataatg ctgcttttga tacaaaggtc ttagcgggat gcttagatta
    38101 ttatcatctt gaacagccta attatctttc tttatgtaca gtgaaaagta gccgtcgcct
    38161 gtttcctgaa tttccaaatc atcgattgaa cactgtgtgc gaaaatttga acatccaatt
    38221 agatcatcac catgatgcat tggaagatag tcgtgcatgt gcggaaatcc tgctttatca
    38281 agaaaaaaaa ttcgggacag atccattgaa aaaacttgtg actataaagt aaaagaatac
    38341 ttatgaaaca cacaaagagg tcgtgagcct gccgtttcac tccgagtcac aaggagcaat
    38401 ttcaaaaaat agcttctcat gtttattaaa tattgtgact ggtgaccgag gagctggcag
    38461 gagaacaccg tttattggag aggttgtgaa aaagctgttc tgcatcaagt aataagaaca
    38521 gccaaacaaa aatagcttct catatttttc atttggttgg acttattacc gcagatgcaa
    38581 gcttttggac accgtttacc
//
LOCUS       DAFBVQ010000021        37755 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.021, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000021 DAFBVQ010000000
VERSION     DAFBVQ010000021.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 37755)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 37755)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..37755
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.021"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(69..689)
                     /locus_tag="LLC22_001245"
     CDS             complement(69..689)
                     /locus_tag="LLC22_001245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340253.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-dependent NADH-azoreductase"
                     /protein_id="HBK5434533.1"
                     /translation="MASVLVVKGHPLTAEESRTVKALTSFLTSYKENHPDDEVTVLEL
                     YRDDIPEIDEELLSGWEALRAGAEFTSLSESQQQKIARFNELTDQFLAADKIVIANAL
                     WNLNIPTKLKAWFDTVNVAGKTFRYTENGPEGLVTGKKALHIQSNGGVYNGQDFASQY
                     VKGILNFVGIDQVDQLFIEGIDYDPDRADELMQNALDKAAALGKSF"
     gene            complement(881..1177)
                     /locus_tag="LLC22_001246"
     CDS             complement(881..1177)
                     /locus_tag="LLC22_001246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBK5434534.1"
                     /translation="MAQSISVQDFNKLPLDADSIVLDTRNTLDYTKNHLSHSLSIPAA
                     ILPRQLKNLDPKKLYYILSYTGRRSEALADQLTANGFRAVYIIGGMEALQSSVA"
     gene            1381..2031
                     /locus_tag="LLC22_001247"
     CDS             1381..2031
                     /locus_tag="LLC22_001247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629554.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR family transcriptional regulator"
                     /protein_id="HBK5434535.1"
                     /translation="MPTQTFFHLPKEKQKRLIEAARIEFSRVPLKEASIANIVKLADI
                     PRGSFYQYFEDKEDLYFYYFETMRRDSSKDMLQLMKESDGDLFKGFESYFSKMIYEIL
                     EGENASFYRNLFMNMDYRASRKVAPHTSRQKTPHDPHKEHKQDAKELLELIDRTKLKV
                     KNDHELELLIQLVMNTVFTTIAHSYRLFSTSEDYSVEQAISEFNLKLSWLKNGVYK"
     gene            2047..3774
                     /locus_tag="LLC22_001248"
     CDS             2047..3774
                     /locus_tag="LLC22_001248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434536.1"
                     /translation="MLKIVKRISLTSAIAAAVFMVIQVLADLYLPTLTSNIIDKGVAQ
                     GDVDYIWHTGFVMIGFSLISILAAIANTFFATRESQKLGKQLRTDVYKKSESLTKDAF
                     DKYGTASLITRTTNDVTQIQMVTQMFLRMMINAPITLIGASILAYQKDHQLTKIFLVV
                     IPVMIILIGGIMYFAVPLFKSMQKKTDRLNLVFREGLTGVRVIRAFDKTRFEENRFDL
                     ANKDYTNTAIKVNTIVALMMPMMTLIMSGTNVAITWFGGHYIADMTLEVGNLIAFMTY
                     AMQILISFMMLSAIFIMVPRAQASADRINEVLDEKIGIHDPENPKTVSFAGKNATLAF
                     NHVNYRYHGAEKLALEDIDFQAKSGEIVAIIGGTGSGKTTLVNLIPRLYDIESGSIQI
                     NGTDISDMTQYNLRELMGFVPQKAVLFSGTIRDNMQYGKPDATDEMIWKALEIAQAKD
                     FVSEMEDGLDSHVEQGGGNFSGGQRQRLAIARALVKTADIYVFDDSFSALDFKTDANL
                     RQALKTNMKESITVLVAQRVSTVMDADMILVLDEGKLVGKGTHEELLATNETYQEIVH
                     SQLREEDLA"
     gene            3771..5663
                     /locus_tag="LLC22_001249"
     CDS             3771..5663
                     /locus_tag="LLC22_001249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434537.1"
                     /translation="MSKTNTRPSHGPAGGPGHGGPGRNLGVKGEKPKNFWGTVRRLFG
                     YMSKRMVAIIAVFVLAIAAVIFQIQTPKVLGKATTEIFKGVMAGAQQMQQGQQVTKFP
                     IDFDKIAQIIATVIVMYLISAVFNFLQQFIMTRVSQRTVYELRHDLEAKMNRVPISYY
                     DTHTNGDIMSRAINDMDNIASTLQQNLTQFVTSAVTLIGVIVMMLSISWQLTLVALLM
                     IPLSLIIVMIVAPKSQVFFADQQKSLGLLNNQVEETYGGHTIVKTFNHTEKDQEVFEK
                     ENQNLYAAGWKAQFISAIIMPLMNFVKNLGYVFVAVLGGVKVANGNMTLGDVQAFLQY
                     TTQFSQPITQLASLMNTIQSTVASAERVFEVLDEEEMSNEKSGLPEEKDTPYKVRFEN
                     VQFGYTPDNLLMTDFNLDVKPGEMVAIVGPTGAGKTTLINLLERFYDVSGGSIRYDGV
                     DTRDLSRDELRAQFSMVLQDTWLFTGSIYDNIKYGNDDATDEQIIEAAKAAHVDDFVR
                     KLPEGYNTVLNEDASNISQGQRQLITIARAFLANPDVLILDEATSSVDTRTEILIQKA
                     MNRLLENRTSFVVAHRLSTIRDADNIIVMNHGSIVETGNHDTLMEKDGFYADLYNSQF
                     SEEEAS"
     gene            6367..7236
                     /locus_tag="LLC22_001250"
     CDS             6367..7236
                     /locus_tag="LLC22_001250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extradiol dioxygenase"
                     /protein_id="HBK5434538.1"
                     /translation="MKDFQLGAATYLKSVAIRVKDRDKMIDFYKNVVGFDLKREENEL
                     AILGTEEAGSEMLLLEESPRANDHMGVIKKLNRFSLIIPSTEEMADILCRIRKMNYPI
                     KEALEDHGRMGILLVDPEENELEIYHEENKNDQREIPETMDQEALLRKSEEKFSKLST
                     GSYFEKIHLNVTNLTKERQFLNHVLGLKVHNEEEGIHVLNEGDFHVGLTEASGGAIDL
                     PTDEVIGLDFLKFMIDTESMEGLIAHLQQLSVDFFLDKKHTVLTIYDAIGIEWWFVSE
                     PKEKNKTDIRCDA"
     gene            7445..8470
                     /locus_tag="LLC22_001251"
     CDS             7445..8470
                     /locus_tag="LLC22_001251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBK5434539.1"
                     /translation="MYPHTKQLILKKMEEGFYPGVAVAFIKENQVETFTAGFAQVVPE
                     KQLMTEDLLFDAASLTKVVATTSLVLRLLEDGKIELDQPLHKYLPEFENQTITLRHLL
                     THTSDIKTWIPNRDKLSQEELIAAYLKLEPGEQLGKEVKYTDAGTILLGLMLEEIYQE
                     TAVEIFQEQVLEPLGMMNSLFLPFPSKKIVPTEQLPSGEVLRGQTHDPKARVLAEHAG
                     NAGLFIDLKDSITFVQMYLNKGKIRNGRFLEEETIDSLLQDQTPKKNGYRSLGWDLKK
                     DVEDGHAILFHTGYTGTFFLIDIKTQEALIFLSNRVHPVDHRAEYLICRDEIVENFLK
                     EKAVLPK"
     gene            8509..9459
                     /gene="manA"
                     /locus_tag="LLC22_001252"
     CDS             8509..9459
                     /gene="manA"
                     /locus_tag="LLC22_001252"
                     /EC_number="5.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannose-6-phosphate isomerase, class I"
                     /protein_id="HBK5434540.1"
                     /translation="MQEPMFLKPVFQEKIWGGSRLRSVFGFDIPNDKIGEDWAISAHP
                     HGVSVVENGEFKGKRLDELWSEHKELFGHPSEPVFPLLIKILDAEDDLSVQVHPDDAY
                     GMKHEGELGKTECWYIIDAEPGAEIIYGHHAKTREELAEMIKDGRWDDLLKKVPVKKG
                     DFFYVPSGTIHAIGKGIMILETQQSSDTTYRVYDYDRKDAQGQTRELHIQQSIDVTTV
                     PAKTPELQIKEVRKGNSSIVTYLETEFFNVYEWDIKGITSFKKQAPYTLMTVIEGAGD
                     LVVDGKTYPLEKGTSCIIPNGVSEWAVQGELAIIASEPGK"
     gene            9553..11256
                     /locus_tag="LLC22_001253"
     CDS             9553..11256
                     /locus_tag="LLC22_001253"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5434541.1"
                     /translation="MEYKWKANNSSRVSMKQLRKAGHHLNEMIMPNLSLFIAWGILSL
                     ATKGVSGDLHTTLEEVCHWMIQLLLPILISYSGGKSVGGQKGAVAGAIASLGLIARSN
                     APQIVGAMIIGPLAGIVYEQFVSRFHVKFKAGYEMLVSNLLVGLTGSVICIIGIVFIE
                     PVLNSVHLLLASVVSWLVTMNLLPLVSLILEPLKVLFFNNAINHGVLTPLGIEFSQTV
                     GYSSLFLMEANPGPGLGILLSILCFAEKQEKVNASGALMIHAIGGIHEIYFPFVLLRP
                     YLFLAVMAGGASGTLIFQWLDTGLAAPVSPGSLLVIFANAPYPQLAGVSIGIAISTFV
                     TFICAAILLKLPNKEKENKTVKKRGEILEPSIIHSVIFACDSGMGSSAMGAALLKKKL
                     AAEKIDLSVGYSSIYELNNQVNQLVIVQHELAGLAREKVPQSQIYVLDHFLETDILLS
                     RIKEAIQFPKREEKKEIADITEQKTSPANIVFLYKNNRRGSQTMGMTILSQLAKKAKK
                     QFVISKESIEKIKIQEETIYIAQRELAVTEQLEEKIPRLVLVEHWVATNEYEKLVKGE
                     I"
     gene            11258..13291
                     /locus_tag="LLC22_001254"
     CDS             11258..13291
                     /locus_tag="LLC22_001254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374766.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BglG family transcription antiterminator"
                     /protein_id="HBK5434542.1"
                     /translation="MYLSPREKQLLAEFLSSPSPVSIQKMMNLLKVSKRTIYRELDNL
                     EVSLKSVNASLKKAARGSFVIEASEEVLEQLKENTDGKSNDLSTAKRQHAILAELLLT
                     TEPLSLAHFMESYRISNTTFYADIKQLEESIRQLPLEIIRNQGYEIEGPEKYRRLLTA
                     NVLELEINEYELFHSISFDASLNYFFRFVDPQHLSLARKVIGEELIQKKTNLSDRKLE
                     HLVLMLTLTMERVTKNHLLTNETYNSLANKELLQTAKRLFSRIASETKQLYPVNEIVF
                     FAGLLNDFTNSFDQNFFEETFDTQLAYLVKQLIQEVSEETNVHFYEDETLYKMLLTHL
                     SGVFSRAVLQEETLTNPILEKIMVQYEEVANAIRKAVERIFQEKKLSEEEIAYMVLHF
                     ANSLERSPKESNISIAGFSPSGLASTSMLELRLKRYFPFIQQIHFYRIADLKKIDLQE
                     EYDVVISTSILPGYGGKYILVSPLLLEDEVKQLKEAFSHIEKKKRQKITYNSNNEWMI
                     EDTYEETMHFMDQINQLLGRFFIQELDNPETISETIRSLFPYFPEGLVTDEEVVHRRL
                     LKRYEQAPIGIPHTNMGLFHTSSSLISKPIFCIFNLKHPLTIEGMDRQPVDLSRMLVM
                     LAPSPIQEKDGILLGKISGAIIMNDLNTEIFRSGNKEIVYQLLAKILIEEIKK"
     gene            13302..13742
                     /locus_tag="LLC22_001255"
     CDS             13302..13742
                     /locus_tag="LLC22_001255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5434543.1"
                     /translation="MIQLPAEKILLDQSYQNWKEALTEIGQWMTQQGGIKPAYIQSMI
                     ERQEKASVYIGNFVALPHGTDKDEEVVEEGIYLVQVPDGVDFGTKEEPKIATLLFVVA
                     LKKEHQLAVLQDLAFFCSDIDQVMALSDAETIEEVQMIFEHGHI"
     gene            complement(13942..15069)
                     /locus_tag="LLC22_001256"
     CDS             complement(13942..15069)
                     /locus_tag="LLC22_001256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287252.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434544.1"
                     /translation="MSLLTFERNLLLKNKVNFLFPLLLVVLFAFPLFFDHKLAYTEFD
                     ELNHNYEEMQRLIETLKEDENEKEFVESLEKSNKLIEAILHAKNTGNVQQMVEATYHY
                     EKDILDRLISGQRQGIPIIEQQKRVELLRYMKEHQIQRYSIFDLPAHLSLANYYENIF
                     SGMISSFLILCITALFLSSIISYEKRKQVISLVNLLPDSMVKKHSIRFTIYYGAAMLS
                     LVMPFLIVSILVIIKNGLGDFRYPVGTIIGQEIRILPMYEYLFQSFLFLLLWVLFLST
                     ISFLLSALFEHSLVNLLGTLLCLFLAEYRLFSSIGWIESISHYLPTSYVDFQNVIIGG
                     DIFSPLASEQVTFMNGILTLGIWSIVLLFIGMGTIYIKKSY"
     gene            complement(15072..15749)
                     /locus_tag="LLC22_001257"
     CDS             complement(15072..15749)
                     /locus_tag="LLC22_001257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335204.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434545.1"
                     /translation="MTLLIKNMNMKRGKKRVIRQLNLLVESGEVAALIAPNGFGKTTL
                     LNGIAQLLPTTYDQLSLHNISPTAYTDYRRSFFFLESTNQLSDYLSAVDYLTLIKYYW
                     QSKVECQTVFQRLKMTEYLTLPIGKMSLGMKQHVLLAAYLISDSSVMLFDEPLNGLDP
                     GSIDILNSLIRQWQKEGKTILLSSHAIANIQSICSKACFLKNGEIVTESSNMEEILAI
                     YRKLYEV"
     gene            16013..17779
                     /locus_tag="LLC22_001258"
     CDS             16013..17779
                     /locus_tag="LLC22_001258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS mannitol transporter subunit IICBA"
                     /protein_id="HBK5434546.1"
                     /translation="MERTIPKNNISLKARVQKLGSTLSSMVMPNIGALIAWGVLTALF
                     IPDGYLPNEAFATMVSPMLTYLIPLLIGYTGGKVIAGDRGSVVGAIATMGVIVGTDIP
                     MMLGAMIMGPLGGYAIKKFDQLFQKRIKSGFEMLVNNFSAGLIGFGLALLGFSAIGPV
                     VDALTQAMAKGVEIILSAHLIPLTSIFIEPAKILFLNNAINHGILTPLGTEQVAEAGK
                     SILFLLEANPGPGLGVLLAFTLFGKGAAKSSAPGAMIIHFLGGIHEIYFPYVMMKPLL
                     FLSVIGGGMSGSFIFQLMDAGLRAPASPGSIIAILAMTPFNSYLPVILGVIVAAAVSF
                     GISAVILKADAKDTNEDFEKSVQETKAAKQASKGAQGIPQGATFSGVQKIIFACDAGM
                     GSSAMGASILRKKVQEADLPQTVTNQAISQLTDDSNTLIVTQVELQERAKQKAPSARF
                     VSVENFLNSPRYDEIIQELSSKQKTSVSEIENEPAEEFLSANIKQIKEILLVHDDRSG
                     SATMGMTVLKDILDKNHLTIPLRKVNIQDLKDEPDSLIVAKESLAEKVQMAAPQSIHL
                     SVNSMVNPQKYESIAQYLKQTA"
     gene            17794..18231
                     /locus_tag="LLC22_001259"
     CDS             17794..18231
                     /locus_tag="LLC22_001259"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5434547.1"
                     /translation="MQSLPFDMIELNRSFKTKEEAIRYCGQMLVEAGCVDEEYIDAMV
                     DRDKMLSVYMGNFIAIPHGTDEAKKYVKKSGICVVQVPDGVDFGTEEEEKIATVLFGI
                     AGVGDEHLQLVQQIALYCSDMDNVVQLADALSKEEVTENLAIA"
     gene            18244..19395
                     /locus_tag="LLC22_001260"
     CDS             18244..19395
                     /locus_tag="LLC22_001260"
                     /EC_number="1.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannitol-1-phosphate 5-dehydrogenase"
                     /protein_id="HBK5434548.1"
                     /translation="MRAVHFGAGNIGRGFIGEVLAANGFEITFVDVNHTIIDALNERK
                     EYEIELADESKEKITVKNVKGINNQTNPEKVIQEIAEADLVTTAIGPNILPFIAELIA
                     KGIQEREKEGSTTSLDIIACENMIGGSAFLEKEVYKYLPETSFTDKYIGFPNAAVDRI
                     VPLQHHEDPLFVQVEPFKEWVIDDSQRKNKKIQLKGVLYVDDLEPYIERKLFSVNTGH
                     ATVAYTGALLGYQTIDEAMQDALVVAQLKSVLQETGSLLIAKWGFDAEQHHAYIEKII
                     HRFQNKNISDAITRVARTPLRKLGYQERFTRPVRELQEHNLTCPHLTATMGIIFNYYD
                     PEDEQSRQLHEMKIHENLEQLIQEVTGINDPKTIGNIKQNVNRYAKQVA"
     gene            complement(19457..20155)
                     /locus_tag="LLC22_001261"
     CDS             complement(19457..20155)
                     /locus_tag="LLC22_001261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 1 glutamine amidotransferase"
                     /protein_id="HBK5434549.1"
                     /translation="MANYELNIAHLYGNLMNTYGDNGNLLMLKYIAEKMGVSCHTEIV
                     SIHEPFDADKYDLVFFGGGQDFEQLIISKDIQKKKDSLINYIENDGVMLAICGGYQLL
                     GHYYMGANGEKIQGISALDHYTLSQENNRFIGDIVIHNEEFNETYYGFENHNGRTFLG
                     EGERPLGKVVQGQGNNGEDQSEGVIYRNVFGSYFHGPILARNENLAARLIRLALEQRY
                     GKELDLPYLEGQTA"
     gene            complement(20148..21500)
                     /locus_tag="LLC22_001262"
     CDS             complement(20148..21500)
                     /locus_tag="LLC22_001262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mur ligase family protein"
                     /protein_id="HBK5434550.1"
                     /translation="MGIRSHFAIAVGKTSQWALKTFFKGGSSLPGKLALKVDPHILDS
                     LAKDYQVVVVTGTNGKTLTTALTVNILRQQFDEVLTNPTGANMVQGIVSTFLQAKPKK
                     GQKKFAVLEIDEASLSKVTEYMKPELFLFTNIFRDQMDRYGEIYTTYKMIVDGAAKSP
                     NATIISNGDSPIFNSIETVNPRKYYGFDHEEDREQMAHYNTDGVLCPNCHHILHYKMI
                     TYANLGKYYCPNCDFKRPELDYRLTDMVRMDNVSADFVIDGHEYGIEVGGMYNVYNAL
                     AATAVAEYFNVDPDKIKQGLGYDEKVFGRQEVININGKKCTLVLVKNPVGINQVIDMI
                     GLAPYPFSLVALLNANYADGIDVSWIWDGNFENFADMDIPAVISGGDRHTDMTLRLKV
                     AGIPENKLTETKELPEVIEKIKELPTEHVYILATYTAVLQLRKELAAQGFIKGGMNRG
                     "
     gene            complement(21723..23123)
                     /locus_tag="LLC22_001263"
     CDS             complement(21723..23123)
                     /locus_tag="LLC22_001263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkH family potassium uptake protein"
                     /protein_id="HBK5434551.1"
                     /translation="MHVDLFFRRLQRRGQKFAANHFSSIQIIVFYYILMTVLSLVLFY
                     MPIFREPDSHVSFVDMLFMAISTVSVTGLSTFDINSVFNDNGIILLEILFQVGGLGIM
                     MISTAFVIFSKRRITLKQRQLIMTDMNQPRLSGIVRLIRITFAILIWFQLLFGTFFSI
                     YFYYRGYFDRWRDAVFYGFYQAISAVTNSGFDVTGDSIKPFAHDYFFLILIMFLIFVG
                     GIGFPVLMECREWLLYKRSNAKLPFRFSLFTKLAVLAFVILFVSGTVLIYLLEKDHLF
                     QDSNMSVKWINSMFYSITTRNAGLQIHDLGDFQITTLIIFSLLMFIGCSPSSVGGGIR
                     TTTVAIIGLYLYSFLKSEDNINIFGRRIDQDDVRKSVVVFMLSLGMCFFCIVFLSATE
                     EQTLISIIIEVTSAFGTTGLSLGITGDLSVVGKITIATLMFIGRIGMLYTLMLFVPKE
                     TRDLGYEYPSEKIIIG"
     gene            23284..24021
                     /locus_tag="LLC22_001264"
     CDS             23284..24021
                     /locus_tag="LLC22_001264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325405.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="epoxyqueuosine reductase QueH"
                     /protein_id="HBK5434552.1"
                     /translation="MINAQQIVEKMKNQKINYDTVLKKMIMQWEKEEVKPKILIHTCC
                     APCSTHTLEFMSQYAEITLFFSNSNIHPKSEYLRRLHEQKRFVDQFNEKTDHHVALIV
                     DEYRPNEFTKMVLTNHLENEKEGGARCSACFNMRLDLVAQKAQELGYDYFGSALTISP
                     KKNAALINQIGMDIQKIYGTQYLPSDFKKNKGYERSLQMCKEYDIYRQCYCGCVFAAK
                     QQGCDLKEINREAKAYLKTSTVVFEEN"
     gene            24146..24625
                     /locus_tag="LLC22_001265"
     CDS             24146..24625
                     /locus_tag="LLC22_001265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A-agglutinin attachment subunit precursor"
                     /protein_id="HBK5434553.1"
                     /translation="MRKVAPILKPIAVLTISTIVATTTGIVNSSSYRAPSSSSSTVEE
                     TTPTTSVSTSEPTTTESLNETTTTSTWDDTTTSSSYDETYTTDSSSETSNTVPDGTPS
                     DSTNPSTSPDTSASSETIPSSTTVDDNTQNDDAARTAQQNQDSGNTQTYNQQAGDSQ"
     gene            24622..25389
                     /locus_tag="LLC22_001266"
     CDS             24622..25389
                     /locus_tag="LLC22_001266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434554.1"
                     /translation="MTFLLDLINGVHKFLGYLDISPKYLNRGYTILSVIPTLYLLRIV
                     YGLWQNQNYLQFFLYGLAFLVLVYFTVLNVFYYFLDKNTKADVTQLFVKYLPDEAFNI
                     QTEESIDNGNSIDKVNTQEVMVSYDEDYQLKLAENMRYLIGNGEIKTNELGRMDGFLV
                     DRNTLYPYYYVKKTGEKEYVLNIGRSYSDMEKVGTIRLDSTEDTLEPVGLFIVGGDFV
                     KDGLRYHEPYRLKLIAKKAQSQEEPVVYSRSQRRRHS"
     gene            25619..26188
                     /gene="lepB"
                     /locus_tag="LLC22_001267"
     CDS             25619..26188
                     /gene="lepB"
                     /locus_tag="LLC22_001267"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK5434555.1"
                     /translation="MKEFLKNWGILILVLAAILLARVYVFTPVTVNGHSMDPTLSDGQ
                     RLISSKISNYERMDIITTKEPGDEERMIVKRIIGMPGDTVKMENDQLTINGKKYDEPY
                     LDEFKKEFSEDKLQGEYAYSSGFQAQAESSSTFTSDFEYTVPKGKYLVLGDNRLISKD
                     SRMFGLVDKDMIQGKVVFRYWPLSEIKIM"
     gene            complement(26292..26894)
                     /locus_tag="LLC22_001268"
     CDS             complement(26292..26894)
                     /locus_tag="LLC22_001268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5434556.1"
                     /translation="MTKNIFDSIANHYDSPDRQALAKIIREELTTYLPRDSHQKVLLD
                     YGGGTGLVSLPLAERFKELIIADASETMLKMAEEKIQAADLKNVRTIHADASVEFPAV
                     QANLILLSLVLLHIPDTENILTKLYEILAPGGQLIIVDFDKNEQISHPKVHNGFSQEE
                     LNNRLEKTGFVSATSHTFHRGEKLFMNKNASLFLSISQKA"
     gene            27000..27469
                     /locus_tag="LLC22_001269"
                     /pseudo
     CDS             27000..27469
                     /locus_tag="LLC22_001269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325408.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
     gene            27575..28159
                     /locus_tag="LLC22_001270"
     CDS             27575..28159
                     /locus_tag="LLC22_001270"
                     /EC_number="2.7.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidine kinase"
                     /protein_id="HBK5434557.1"
                     /translation="MAQLFFKYGAMNSGKTIEILKVAHNYEEQNKPVVLMTSGIDTRD
                     GLGVVSSRIGLKRNAMPIFEETDVFDVIQKMESKPYCVLIDEAQFLKKKHVIAFTRIV
                     DELDIPVMAFGLKNDFRNELFEGSKYLLLYADKIEEMKTICWFCHKKAIMNLHYIDGN
                     PVYEGDQVQIGGNEAYYPVCRKHYFHPSMITEGE"
     gene            28162..29235
                     /gene="prfA"
                     /locus_tag="LLC22_001271"
     CDS             28162..29235
                     /gene="prfA"
                     /locus_tag="LLC22_001271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003128515.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 1"
                     /protein_id="HBK5434558.1"
                     /translation="MYDQLQAIEDRYEELGELLSDPEVISDTKRFMQLSKEEANTRET
                     VEVYRRYKEVVQGITDTEELLGEKLDDEMAELAKEELSELKKEKEVLEEKIKILLLPK
                     DPNDDKNIIMEIRGAAGGDEAALFAGDLFNMYQKYAEAQGWKTEVMEANVTGIGGYKE
                     VIMMITGDNVYSKLKYESGAHRVQRVPSTESQGRIHTSTATVVVMPEAEEVEIDIEDK
                     DIRTDIYHASGAGGQHVNKTASAVRLTHLPTGIVVAMQDERSQIKNREKAMKILRARV
                     YDKIQQEAQSEYDANRKSAVGTGDRSERIRTYNFPQNRVTDHRIGLTIQKLDQILAGK
                     LDEIVDALIMYDQTSKLEAMQNG"
     gene            29228..30067
                     /gene="prmC"
                     /locus_tag="LLC22_001272"
     CDS             29228..30067
                     /gene="prmC"
                     /locus_tag="LLC22_001272"
                     /EC_number="2.1.1.297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor N(5)-glutamine
                     methyltransferase"
                     /protein_id="HBK5434559.1"
                     /translation="MGKMTYREVLSRASSFLEDHGKEAYSIQFLFLERKQWKKLDWLL
                     HMNEEISEEEQRLIETDLRLLLADHPPQYLLGYADFYDHRLKVTEATLIPRPETEELV
                     EWCLDETPGVPLEVIDIGTGTGAIAISLKAARKNWHISAVDLSEEALEVAKENAQKEG
                     TKISFYHGDTLGPVMDQQFDVIISNPPYISRNEWELMDESVRSFEPKMALFAENDGLA
                     IYEKIAVEAPSVLKSNGKIFLEIGFRQGEAVKKIFQQAFPDKKVAIKKDLFGNERMIQ
                     VYG"
     gene            30060..30239
                     /locus_tag="LLC22_001273"
     CDS             30060..30239
                     /locus_tag="LLC22_001273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434560.1"
                     /translation="MVEVVDEKFFICFFIIKKHLFDKDVNDFLVYQQVYPLLTNRLST
                     NSGKLEDKLRQNKNV"
     gene            30261..31286
                     /locus_tag="LLC22_001274"
     CDS             30261..31286
                     /locus_tag="LLC22_001274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonylcarbamoyl-AMP synthase"
                     /protein_id="HBK5434561.1"
                     /translation="METKRYDETELQEAAEALKEGELVAFPTETVYGLGANALLPNAV
                     KKVFSVKGRPQDNPLIVHVASFEQVKEYVDNFHPAAEKIVKNFWPGPLTLIFKIKKDT
                     LPSVVTGGLSTAAFRIPDNKKTLEVIELSGVPLVGPSANTSGKPSPTTADHVYHDLQG
                     KITGIIDDGATRIGVESTVLDLSDPTAMPMILRPGAVTKEQIEAVIESPVAIDQHLVK
                     ENETPKAPGMKYKHYSPDTRVLMVRDGDWSTAVQWAKNKKIRAGVIASPEIADQVRTD
                     TAAVYMYNDNSVEAAAKGLFAGLRGLDEPTLGLDLIFVQVYPETGLGNAYMNRLKKAA
                     GQNYFEK"
     gene            31461..32705
                     /locus_tag="LLC22_001275"
     CDS             31461..32705
                     /locus_tag="LLC22_001275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydroxymethyltransferase"
                     /protein_id="HBK5434562.1"
                     /translation="MVDYKTFDPDLWAAIAKEEERQEHNLELIASENFVSEAVMAAQG
                     SILTNKYAEGYPGHRYYGGCEFVDIVENLAIDRAKELFGAKFANVQPHSGSQANTAAY
                     LALVEPGDTILGMDLSAGGHLTHGSPVNFSGKTYHFVAYGVDPTTEVIDYNVVRILAR
                     KHQPKLIVAGASAYGRTIDFAKFREIADEVGAKLMVDMAHIAGLVAAGLHPNPVPYAD
                     ITTTTTHKTLRGPRGGMILTNDEALAKKINSAVFPGIQGGPLEHVIAGKAVAFKEALD
                     PAFKEYSEQIIANAKAMVKVFNQAIGTRVISGATDNHLMLIDVRELGINGKEAESILD
                     SVNITVNKNSIPFETLSPFKTSGIRIGTPAITTRGFKEEDAVKVAELVVKALQAKDDN
                     AQLDEVKTGVRELTEKFPLHKK"
     gene            32858..33805
                     /locus_tag="LLC22_001276"
     CDS             32858..33805
                     /locus_tag="LLC22_001276"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5434563.1"
                     /translation="MTDRISLEKEAVAFSDANAPHPRIYELAPEEGRVLLEEVQESPV
                     NKYSVDIEDLMVDTGEWGKLNIRLVRPEGNMDKLPVIFYIHGAGWVFGSAQTHDKLIR
                     ELAVRTNSVVVFPEYSRSPEAKYPTAIEQNYAVLQQLNKLAKSKNLDLENLIVAGDSV
                     GGNMATVMTILTKERKGLPISKQLLYYPVTNADFDTDSYHEFGENYFLTREGMMWFWD
                     QYTTNEEERAEITASPLRANINELNDLPSAMILTGEADVLRDEGEAYARKLRDAGVPV
                     TQVRFQGIIHDFVMVNAMDQTKATRAAMALSTSWIKKKE"
     gene            33939..34568
                     /gene="upp"
                     /locus_tag="LLC22_001277"
     CDS             33939..34568
                     /gene="upp"
                     /locus_tag="LLC22_001277"
                     /EC_number="2.4.2.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013774406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil phosphoribosyltransferase"
                     /protein_id="HBK5434564.1"
                     /translation="MGKFQVIDHPLIQHKLTIIRDKNCGTKVFREVVDEIAMLMAYEV
                     SRDMPLEDIVIETPITETTQKTLSGKKVAIIPILRAGIGMVDGILELIPAAKVGHIGL
                     YRDEETLEPHEYFVKLPEDIDARQLFVVDPMLATGGSAIMAIDALKERGASNIKFVCL
                     VAAPEGVKALQEAHPDIDIYTASLDEKLNEHGYIVPGLGDAGDRLFGTK"
     gene            complement(34707..34949)
                     /locus_tag="LLC22_001278"
     CDS             complement(34707..34949)
                     /locus_tag="LLC22_001278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719992.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434565.1"
                     /translation="MKMATFGKFDTTIVPSEIGEKFKINTHVMFTIHGKSQTGTISKQ
                     LKNSAVVEIDETAENANLMTQSKGVVIVNYKELKKI"
     gene            35070..35142
                     /locus_tag="LLC22_001279"
     tRNA            35070..35142
                     /locus_tag="LLC22_001279"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:35103..35105,aa:Thr,seq:cgt)
     gene            complement(35261..35899)
                     /locus_tag="LLC22_001280"
     CDS             complement(35261..35899)
                     /locus_tag="LLC22_001280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK5434566.1"
                     /translation="MNNILGKKIELKKGKLGTIVVVLGLLGLLFAPSIISIFSLTITG
                     FIAFTLVFGKKDTKKMFSKPVAPVKNIAKYFFINVVISAAVSVFLQQILKWGLTGNPI
                     NEAFSPLLFIILPIMILGEELFSVYFLAIFSSKFSIPVASFLSAIIFGFIHYSTYDNG
                     NILHTVAHILLIQGVARLLFNQAAIKSNSIITSWAVHVIFDFTAILLVVLFS"
     gene            complement(36022..36654)
                     /locus_tag="LLC22_001281"
     CDS             complement(36022..36654)
                     /locus_tag="LLC22_001281"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBK5434567.1"
                     /translation="MIFPKVNEASLNKGSFFHIYENEDFELYNILSQKEVIENQIICH
                     PIIYKSIFKYAFFASNDFQRMEITDCIFENCDFSGCILTKSMLHRVKFVNCKLTGTKL
                     MESYIGNTLFENCKMDYVNLSGSNIKESTFEHSVLSSADFVDCSLTKIMFSTNDLENA
                     SFFDTDLKNIDLSSNSFEMIEVRSEHLKNCTLNQLQALGFARKFLQIKVV"
     gene            37005..37304
                     /locus_tag="LLC22_001282"
     CDS             37005..37304
                     /locus_tag="LLC22_001282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBK5434568.1"
                     /translation="MSKSEEIENMVLKLYDLVLNPEIKEKERILLIDAKTGLEKGQYY
                     PKVINNLERSLRPLAIRGELSKPVSPFYMEISTIGKFEKELGRGMASAPITFGHL"
BASE COUNT        12767 a         6615 c         7601 g        10772 t
ORIGIN      
        1 atccaaggca caaatgctgc tttgaagatt ttttcctctg tctcttttgt atgcatttat
       61 ctcaattttt aaaatgattt acctaaagca gcagctttat ctaatgcatt ttgcatcaac
      121 tcatctgcac ggtcagggtc ataatcgatt ccttcgatga atagctgatc tacttgatcg
      181 atgcctacaa agtttaaaat accttttaca tattgagagg caaagtcttg tccgttgtat
      241 acaccgccat tagattggat gtgcagtgct tttttacctg tcactaatcc ttctggcccg
      301 ttttctgtat agcggaacgt ttttccagct acattgacgg tatcgaacca agcttttaat
      361 tttgttggga tatttagatt ccataaggcg tttgcgataa cgattttatc agcagcaagg
      421 aactgatcag tcaattcatt gaaacgagca attttttgtt gttgactttc tgataaggaa
      481 gtgaattctg caccagcacg taatgcttcc caacctgata ataattcttc atcgatttcc
      541 ggaatatcat cgcgataaag ttccaaaaca gtcacttcat catctggatg attttcttta
      601 taacttgtta aaaaagacgt caatgcctta actgtgcgcg attcttctgc agttagggga
      661 tgacctttga ctactaaaac agatgccata tgcttacctt ctccttttat tgctatgatt
      721 gttataacta tgactaacaa aatcagttta ctcgaaaaag aaaaggctat caagtcatat
      781 tgataaggtt gaagaataaa taactaaaaa aagacagggt ataaaagagg ctgtgacacg
      841 attttttgtc acagcctctt ttgaatctaa caagcaatat tcaagcaaca ctcgactgaa
      901 gagcttccat cccaccaatg atataaacag cacgaaaacc attagcagta agttgatcgg
      961 ctaatgcttc tgatcgcctg cctgtatagc ttagaatata ataaagtttc tttggatcta
     1021 gattttttaa ttgtcttggc aagatagcag cggggataga aagcgagtgg cttaagtggt
     1081 tttttgtgta atctaaggta tttcttgtat ctaaaacgat gctgtcagca tcgagaggca
     1141 atttattgaa gtcttggaca ctaattgatt gggccattta tctcatcctt tgtttagtat
     1201 gtggctattt taatgggcaa ctctcattaa ttcaaatgga aggattcctc ttatcacttt
     1261 tttaatgtat cggatgataa tgaaaaaaac tatgcaaatg tcttgcaaaa caggtaggag
     1321 gtgttataat gacatagcgt catatgacaa tgtgtcatct tgaaagaaag gagaatccat
     1381 atgccgacac agacattttt ccatttgcct aaagaaaaac aaaaaagact aatcgaggct
     1441 gcgagaatcg agttttctag agtaccctta aaagaagctt cgattgctaa tatcgtcaaa
     1501 ttagcggata tccctagagg cagtttctat cagtattttg aagataaaga ggatctttat
     1561 ttttattact ttgagacaat gagacgtgac agctctaaag atatgttaca actaatgaaa
     1621 gaatccgatg gtgatctatt caaaggattc gaatcctatt tttctaaaat gatttatgag
     1681 attttggaag gcgagaatgc ttctttttat cgtaacttgt ttatgaacat ggattaccgt
     1741 gcctcaagaa aagtcgctcc tcatacgagt cgccaaaaaa cgcctcacga tccacataaa
     1801 gaacacaaac aagatgcaaa agagttgctt gaattgatcg atcggacgaa gctgaaagta
     1861 aaaaatgatc atgaattgga attactgatc caattagtga tgaatactgt atttacaaca
     1921 attgcgcatt cgtatcgctt attttcaaca tctgaagatt actcagtaga gcaagcaatc
     1981 agtgaattca atttgaaact ttcttggctg aaaaacggag tatataaata gaaagaaggg
     2041 aactagatgc taaaaatcgt aaaacggatc tccttgactt cagcaattgc agctgcagtt
     2101 ttcatggtga tccaagtact ggcagattta tatttgccga cacttacctc caatattatt
     2161 gataaagggg tagcgcaagg agatgtcgat tatatttggc atacaggttt tgtgatgatc
     2221 ggcttttctt tgatcagtat cttagctgct atcgcaaata cattttttgc tactcgtgaa
     2281 tcacagaaac tgggtaagca attgcgtacg gatgtctata aaaaatcaga gagtctgaca
     2341 aaagatgcgt ttgataaata tggaacggcc tctttgatca caagaacgac caatgatgtg
     2401 actcaaatcc aaatggttac acaaatgttt ttacgtatga tgatcaatgc accaatcacg
     2461 ttgattggcg cgagcatact tgcttatcaa aaagatcatc agttgacaaa aatcttctta
     2521 gttgtcatcc cagtaatgat tattttgatc ggcggaatca tgtactttgc tgttccatta
     2581 ttcaaaagta tgcaaaagaa aactgaccgt ttaaacctgg tatttcgaga aggattgaca
     2641 ggggtcagag tgattcgagc attcgataag acacgctttg aagaaaatcg ttttgattta
     2701 gcgaataaag attatacaaa tacggcaatc aaagttaata cgatcgtcgc attgatgatg
     2761 ccaatgatga cattgatcat gagcggtaca aacgtagcaa tcacttggtt tggtggacac
     2821 tacatagcag atatgacttt ggaagtcggt aatctgattg catttatgac ttatgcgatg
     2881 cagatcttga tcagctttat gatgctttcc gctattttta tcatggtgcc tcgtgcacaa
     2941 gcttcagctg accgtattaa tgaagtgttg gatgaaaaaa tcggtatcca tgaccctgaa
     3001 aatcctaaaa cagtttcttt tgctggaaaa aacgcaacat tggccttcaa tcatgtcaat
     3061 tatcgatatc atggagcaga aaaacttgca ttggaagata ttgatttcca agccaagtcg
     3121 ggcgagatcg tcgcaatcat aggggggact ggttcaggta aaacgacctt agtcaatttg
     3181 atccctcgat tatatgacat cgaatctggt tcgatccaaa taaatggaac ggacattagt
     3241 gacatgactc aatataattt gcgagaatta atgggctttg ttcctcaaaa agcagttctg
     3301 ttctctggaa cgatccgaga caatatgcag tatggtaagc cggatgcaac agatgaaatg
     3361 atttggaaag cattagaaat cgcacaagct aaagattttg tttcagagat ggaagatggc
     3421 ttagatagcc atgtggaaca aggaggagga aacttctctg gtggacaaag acagcgtctg
     3481 gcaattgcac gggcattagt caaaacagca gatatctatg tgtttgatga ttccttctca
     3541 gcgttggatt tcaaaacgga tgccaatctt cgccaagcat tgaaaacgaa tatgaaagaa
     3601 agtatcaccg ttttagttgc tcaacgagta agtacagtaa tggatgcaga tatgatcctt
     3661 gtgctagatg aaggaaaact ggttggcaaa ggaacacatg aagaactatt agcaacaaac
     3721 gaaacttatc aagaaatcgt tcattcacaa ctaagagagg aggacttagc atgagtaaaa
     3781 caaacacacg tccctctcat ggaccagcag gcggtccagg acatggtgga cctggcagaa
     3841 atctcggtgt aaaaggtgaa aagcctaaaa atttctgggg aacggtacgc cgattgtttg
     3901 gctatatgtc taaacgtatg gttgcgatca tcgctgtatt tgtactagca atagcagccg
     3961 tgatcttcca aatccaaaca ccaaaggtct tggggaaagc aaccacagaa atattcaaag
     4021 gtgtaatggc tggcgctcaa cagatgcaac aaggccaaca agtaacaaaa tttccgatag
     4081 actttgataa aatcgcgcag atcattgcga cagtaatcgt gatgtatttg atttctgctg
     4141 tattcaactt tttacagcaa tttattatga cacgtgtttc ccaacgaaca gtttatgaat
     4201 tacgtcatga tttggaagcc aaaatgaatc gtgtaccgat ttcctattat gatacacata
     4261 caaatgggga tatcatgtct cgagcaatca atgatatgga taacatcgca agcacgctgc
     4321 agcaaaattt gactcaattt gtaactagtg cagtcacatt gattggggtc atcgtgatga
     4381 tgctttcaat cagctggcaa ttgacgttag tcgcgttatt gatgatccct ttaagcttga
     4441 tcatcgtgat gatcgtagcg ccgaaatcac aagtgttttt cgcagatcag caaaaaagtt
     4501 taggtttatt gaataaccaa gtagaagaaa catatggtgg tcataccatt gttaaaacat
     4561 tcaatcatac tgaaaaagac caggaagtat ttgaaaaaga aaatcagaat ctgtatgccg
     4621 ctggttggaa agctcaattt atttcggcaa tcatcatgcc gttgatgaat ttcgttaaaa
     4681 atctaggcta tgtgttcgtc gctgtactag gcggagtaaa agttgcaaat gggaacatga
     4741 cattagggga tgttcaagcg ttcttgcaat atacaacaca gttctctcaa ccaatcactc
     4801 aacttgcaag tttgatgaac actatccaat caacagttgc ttcagccgaa cgggtatttg
     4861 aagtgttgga tgaagaagag atgtccaatg aaaaatctgg ccttccagaa gaaaaagata
     4921 caccatacaa agttcgtttt gaaaatgttc aattcggcta cacaccagat aacttgctaa
     4981 tgactgattt taacttggat gtcaaacctg gtgagatggt cgctattgta ggtccgactg
     5041 gtgcagggaa gacgacactg atcaaccttc ttgaacggtt ctacgatgtt tctggaggta
     5101 gtattcgtta cgatggtgta gatacccgtg atctttcacg tgatgaattg cgcgcacagt
     5161 tttcaatggt actgcaagat acttggctgt ttacaggaag tatctatgac aatatcaaat
     5221 atgggaacga cgatgcaaca gacgaacaaa tcattgaggc tgctaaagct gctcacgtag
     5281 acgattttgt tcgtaaattg ccagaaggat ataacactgt attaaacgag gatgcaagca
     5341 atatttcgca agggcagcgt cagctaatca caattgcgcg ggcattctta gcaaatccag
     5401 atgtcctgat ccttgatgaa gcaacatcta gtgtagatac acgaacagaa atactgattc
     5461 aaaaagcgat gaaccgccta ttggaaaacc ggacaagttt cgttgttgct caccgcttgt
     5521 ctacaatacg cgatgcagac aacattattg tgatgaatca tggttcgatc gtagaaacag
     5581 gaaaccacga tacattgatg gaaaaagacg gattctatgc agatctttat aacagtcagt
     5641 tttctgaaga agaagcttca tagaatagta caaatttatt atttttttta ggggctgtga
     5701 caaaagtcgt gtcacagtcc ctttttccga ataaacggtg ttcaatcagc tgtccttcgg
     5761 tattagctca aaaaacggca aaatatgaga agctattttt ccgttttgta tctctaatac
     5821 tcaggtcaaa ccgctgattt tacaacctct tccttaaacg gtgttctcct gccaactcct
     5881 cggtcacaag tcacaatagt caacaaacct gagaagctgt tttttgaaat tgctccttgt
     5941 gactcggagt taaacggcag gctcacaacc tcttggtaaa cggtgttcaa aagccagttt
     6001 ctcggtatta agccaaattt atgcaaaaat gtagaaagcc attttcacaa aatttttctt
     6061 actactcgaa actaagcgac tttttcacaa cctcttcctt aaacggtgtt caaaagcttg
     6121 catctgcggt aataagccca accaaacgaa aaataggagg agctattttt gtttggctgt
     6181 tcttattact tgatgcagaa cagctttttc acaacctctt tttataagag tttttactca
     6241 ttaatttaca aaaaacaagc aaaatgcgaa ttttctcaca ttttttttaa caaaatcaaa
     6301 gttattgctt gaaagaagaa gaatccatcg ttaaaataaa gcttgacgta gaggggagca
     6361 agaaatatga aagattttca attgggggct gccacctatt taaaaagtgt agccattcgg
     6421 gtgaaagacc gagataaaat gattgatttt tacaagaacg ttgttggctt tgatttgaaa
     6481 agagaagaaa acgaattagc cattttagga acagaagaag ctggaagtga aatgttgctg
     6541 ctggaagaaa gtcctagagc gaatgatcac atgggggtga tcaaaaagct gaaccgtttt
     6601 tcattgatta tccctagcac agaagaaatg gcagatatcc tttgtcgtat ccgtaaaatg
     6661 aattatccaa tcaaagaagc tttagaagat catggacgta tggggatttt gctcgtagac
     6721 ccagaagaga atgaattgga aatttaccat gaagagaata agaacgacca aagagaaatt
     6781 ccagaaacaa tggatcaaga agcattatta agaaaatctg aagaaaaatt cagtaaacta
     6841 tcaacaggtt cttattttga aaaaatccat ttaaatgtta ctaacttaac aaaagaacgc
     6901 caatttctta atcatgtact tggtttgaag gtacataatg aagaagaggg catccatgta
     6961 ttgaatgaag gagatttcca tgttggtttg acagaagcta gcggaggcgc aattgatttg
     7021 cctacagatg aagtgattgg acttgatttt ctgaaattca tgatcgatac tgaaagcatg
     7081 gaaggactga ttgctcactt gcagcaacta tcagttgatt tcttcttaga caaaaagcac
     7141 acagtactca caatctatga tgctatagga atcgaatggt ggttcgtcag tgagccaaaa
     7201 gaaaagaata aaactgacat tcgatgcgac gcttaacttt ttctttctta acgattgtcg
     7261 catgtctcgt cattttatga acggtcatac tatcgcttat tctagagata gaaagagaaa
     7321 atagtatacc gggggaaact gcgcggtttt tcgcgcagtt tttttgtgta aaaaaggttg
     7381 attcctcata gattaagctt taagcttgga ctgtaagaat ctgatagaaa agcaggagaa
     7441 aaagatgtat ccacacacga aacagcttat tttgaaaaag atggaagaag gattttatcc
     7501 aggtgtagca gtcgccttca taaaagaaaa tcaagtagaa acatttacag ccggctttgc
     7561 ccaagtcgtt cctgaaaagc agctgatgac agaagatctg ttgtttgatg cagcctcact
     7621 gacgaaagtc gttgcaacca cttcattagt tttacgtcta ttagaagatg gaaagataga
     7681 actcgatcaa ccgcttcata aatatcttcc tgaatttgaa aatcagacaa tcactttgcg
     7741 tcatttactg acacatactt ctgatatcaa aacatggata ccaaacagag ataagctatc
     7801 tcaggaagaa ttgatcgccg cttatttgaa gctagaacca ggtgagcaac taggaaaaga
     7861 agtaaaatat acagatgccg gtacgattct tcttgggttg atgctagagg aaatttacca
     7921 agaaactgca gtggaaatct ttcaagaaca agtattggaa ccattaggaa tgatgaacag
     7981 cttatttctt ccttttcctt ccaaaaaaat cgttcccaca gaacaactgc cttcgggtga
     8041 ggttttgcgt ggacaaactc atgatccgaa agcaagagtt ttggctgaac atgcaggtaa
     8101 cgcgggtctc tttattgatt tgaaagacag cattactttt gtccaaatgt atttgaacaa
     8161 gggaaaaatc cgtaatggtc gttttttaga agaagagacg attgattctt tactgcaaga
     8221 tcaaacaccg aaaaaaaatg gctatcgttc tttaggatgg gacttaaaaa aggatgtaga
     8281 agacggtcat gcgattcttt ttcatactgg ttatacaggt acgtttttct tgattgatat
     8341 aaaaacacaa gaagcgttga tatttttgtc aaatcgcgta catcctgtcg atcatcgtgc
     8401 ggagtatctc atatgtcgag atgaaattgt tgaaaacttt ttgaaagaga aagcggtatt
     8461 accgaaataa tgctataata gctatgaaaa atgagaggag tttgaattat gcaggaacct
     8521 atgtttttaa aaccagtttt tcaagaaaaa atttggggag gaagtcgttt acgttcagtc
     8581 tttggttttg atatccctaa cgataaaatc ggagaagatt gggcgatcag tgcgcatcct
     8641 catggtgtca gtgtagtaga aaatggcgaa ttcaaaggga aaagattaga tgaactatgg
     8701 tcagaacaca aggaattgtt tggccatcct tcagaaccag tgtttccatt attgatcaag
     8761 atcttagacg cagaagatga tctatctgta caagtacatc cagatgatgc ctatgggatg
     8821 aaacatgaag gtgaattagg aaaaactgaa tgctggtata tcatcgatgc tgaacctggt
     8881 gcagaaatca tctatggtca tcatgcaaag acaagagaag aactagctga gatgatcaaa
     8941 gatgggcgct gggatgacct tttgaagaaa gtaccagtta aaaaaggtga tttcttttat
     9001 gtaccaagcg gaacgatcca tgctattggt aaaggaatca tgattttaga aacacagcaa
     9061 agttctgaca cgacttaccg cgtgtatgac tacgacagaa aagatgcgca aggacaaaca
     9121 agagagctgc atatccaaca atcgatcgat gtaacaactg tccctgcgaa aacaccagaa
     9181 ttacaaatca aagaagtccg aaaagggaat tcatcgatcg tcacttattt agaaactgag
     9241 tttttcaatg tatatgagtg ggatattaaa ggaatcacat ctttcaaaaa acaagcccct
     9301 tatacattga tgacggtaat cgaaggagca ggagaccttg tcgttgacgg aaaaacatat
     9361 ccattagaaa aaggaacaag ctgtattatt ccaaatggcg tttctgagtg ggcggtccaa
     9421 ggtgaactag caatcattgc gtctgaacca ggcaaatagt tcccagatag ctgaaagcag
     9481 cagacggttt ttcgtttgct gctttttcta cataaaatcc gtccatcaat aaatagaagt
     9541 ctggtgaaaa agatggaata caaatggaaa gcaaacaaca gcagtcgcgt gtctatgaaa
     9601 caactgagaa aagctggaca tcacctaaat gaaatgatca tgccaaatct aagtctgttt
     9661 atcgcttggg gaatcttgtc attagcaaca aaaggtgtgt ctggcgattt gcacaccaca
     9721 ttagaagagg tatgccattg gatgatccag ctgcttttac ccatcttgat cagttattca
     9781 ggcgggaaat cggtaggggg acaaaaaggg gcagtcgccg gtgcaattgc ttctttaggg
     9841 ttgatcgctc gttccaatgc tccacaaatc gtaggagcga tgattatcgg gccgcttgcc
     9901 ggcatcgtat atgaacaatt tgtttctaga ttccatgtga aattcaaggc tggatatgaa
     9961 atgcttgtca gcaacctact agtaggactg actggtagcg ttatttgtat aattggaatc
    10021 gtttttattg aaccagtttt aaatagtgtt cacttgttgc tcgcctccgt tgtgtcttgg
    10081 ctagtcacaa tgaatctgtt accacttgtc agtctgatct tagaacctct aaaagtacta
    10141 tttttcaata atgcaatcaa tcatggtgta ttgacacctt taggaatcga attctcacaa
    10201 acagtcgggt actcttcctt atttttgatg gaggcaaatc ctggacctgg tttagggatc
    10261 ttactttcta tcctttgttt tgcagaaaaa caggaaaaag taaatgcgag tggagcattg
    10321 atgatccatg cgattggcgg gattcacgaa atctattttc catttgtctt gctgcgaccg
    10381 tatctatttt tagctgtaat ggctggtggg gcaagcggca cgttgatatt tcaatggtta
    10441 gatacgggat tagctgcacc tgtatcgcct gggtcactac tcgtgatttt tgccaatgcg
    10501 ccttatccac aactagctgg ggtaagtata gggatagcaa tcagtacatt tgtgaccttc
    10561 atttgtgcag cgatactatt gaaattacca aataaagaaa aagagaacaa aacggtcaaa
    10621 aaaaggggag aaatcttgga accatctatc attcattccg tcatttttgc ttgcgactca
    10681 ggtatgggat caagtgctat gggagccgcc ctgctgaaaa agaaattagc agcagaaaaa
    10741 atcgatcttt ctgtcggata cagctctatc tatgaattga ataaccaagt aaatcagctg
    10801 gttatcgtgc aacatgaact agcgggtctt gcaagagaaa aagtacctca aagtcaaatc
    10861 tatgtactgg atcacttttt ggaaacagat atcttgctgt cacgaataaa agaagcgatc
    10921 caatttccaa agcgggaaga aaaaaaagag atagcagata tcacagaaca aaaaacgtcg
    10981 cctgctaata ttgtattttt gtataaaaac aacagacgcg gctcacaaac tatgggcatg
    11041 acgattttaa gtcaattagc aaaaaaagcg aaaaaacagt ttgttatctc aaaagaatca
    11101 atagaaaaaa tcaaaatcca agaagaaacg atttatatcg cacaaagaga actagctgta
    11161 actgaacagc tagaagaaaa gatccctcgg ctagttctag ttgaacattg ggtagctacg
    11221 aatgaatacg aaaaactcgt gaagggagaa atataagatg tatttatcgc ccagagaaaa
    11281 acaattatta gcagaatttc tcagtagccc gtcacctgta tctatccaaa aaatgatgaa
    11341 tttattgaag gtcagtaaac ggactattta ccgcgaatta gataatcttg aagtctcatt
    11401 gaaatcggta aatgcttctt tgaaaaaagc agctagaggc tcatttgtca ttgaggcatc
    11461 agaagaagta ttagagcaat taaaagaaaa tacagatggg aaaagtaatg acttatccac
    11521 tgctaaacga caacacgcga ttttagccga gttgttactg acgacagagc cgttgagtct
    11581 tgctcatttc atggaatcat atcgcatcag taataccact ttttatgcag atatcaaaca
    11641 gttggaagaa agtattcgcc aactgccttt ggaaatcatt cggaaccagg gatacgagat
    11701 cgaaggaccg gaaaaatacc gccggcttct gacagcgaat gtattagaat tagaaatcaa
    11761 tgaatatgaa ctttttcata gtatttcttt cgatgcatca ctgaattatt tttttcgatt
    11821 cgttgatccg caacatctat ctcttgcacg caaagtaatc ggggaagaat tgatccaaaa
    11881 aaagaccaat ctaagtgata gaaagcttga acatttggtt ttgatgctga cattgacgat
    11941 ggagcgtgtg acgaaaaatc atttactgac aaatgagaca tataatagtc tggcaaacaa
    12001 agaattacta cagacagcta aacgattgtt ttcacggatc gcttctgaga caaaacaact
    12061 ttatccagta aatgagatcg tcttttttgc aggattatta aatgacttca cgaactcatt
    12121 tgatcagaat ttctttgaag agacgttcga tacacagctt gcttatttag taaaacaact
    12181 gattcaagaa gtaagtgaag agacgaatgt ccatttttat gaagatgaaa ctttgtacaa
    12241 aatgctgttg actcatttat ctggtgtgtt ttcaagagcc gttttacaag aagagacact
    12301 gaccaatccg attttagaaa aaatcatggt tcaatacgag gaagttgcga atgcaatccg
    12361 taaagcagta gagcggattt ttcaagaaaa aaaattatcc gaagaagaga tcgcttatat
    12421 ggtccttcat tttgcgaatt cattggaacg aagtccgaaa gaaagcaata tcagtattgc
    12481 aggattttcg ccaagtggat tagcttctac tagcatgttg gaactacgat tgaaaaggta
    12541 ttttcccttc atccaacaaa ttcatttcta tcggattgct gatttaaaaa aaatcgattt
    12601 acaagaagaa tatgatgttg ttatttctac atctatttta ccaggatacg gtggaaaata
    12661 tattttagtc tccccgctac tgctagaaga tgaagtcaag cagctaaaag aagctttttc
    12721 gcatattgag aagaaaaaaa ggcaaaaaat tacgtataac agcaataacg agtggatgat
    12781 agaagatact tatgaggaaa caatgcattt catggatcaa atcaatcaat tactcggtcg
    12841 tttttttatc caagaactgg ataatcctga gacgatttcc gaaacgattc gcagcttatt
    12901 tccttatttt cctgaaggac tagtaacgga tgaagaggtg gttcatcgcc ggctgcttaa
    12961 gcgatatgaa caagcaccta tcggtattcc tcatacaaat atggggttat tccatacatc
    13021 cagctcattg atttctaaac cgatcttttg tattttcaat ttgaaacatc cgttgaccat
    13081 tgaagggatg gatagacagc cagtcgattt gtcccgtatg ttagttatgc tggcgccttc
    13141 gccaatccaa gaaaaagacg ggattctttt aggaaagatc agtggagcaa tcatcatgaa
    13201 tgacttgaac accgagatct tccgctcagg aaataaagaa atcgtttatc agttgttagc
    13261 gaaaatcctg attgaagaaa taaagaaatg aaggtgaaaa gatgatacag ctaccagcag
    13321 aaaaaatatt gctcgatcaa tcctatcaaa attggaaaga agcgttgacc gagatcggcc
    13381 agtggatgac ccaacaaggg ggaatcaaac cggcatatat ccaatcaatg atcgaaagac
    13441 aagaaaaagc gagtgtctat atcgggaatt tcgtagcctt gccacatggg actgacaaag
    13501 atgaagaagt agtagaagaa ggaatctatt tagtccaagt gcctgatggt gtggactttg
    13561 gaacaaaaga ggaaccaaaa atcgcgacac tcttatttgt agtggcttta aaaaaagaac
    13621 atcagttagc ggtgctccaa gatttagcct ttttctgttc agacatcgac caagtaatgg
    13681 cgctcagtga tgcggaaacc attgaagaag tccaaatgat ttttgaacat ggacatatat
    13741 aaccaatgtt cacagtaaaa aaagctgcct tgcatcaagt aataacttca accaagataa
    13801 aaataagagg agctattttt gttgggaggt tcttattact gcggatgcaa gcttttgaaa
    13861 actatttatt ctagaaaacc gtttatttga aataggggac ggtgacaagg tttttgtcac
    13921 cgcccctatt atttttgtgt tttaatagct cttttttata tagatagtgc ccatacctat
    13981 gaataataaa acgatactcc atataccaag tgtcaagata ccattcatga aagtaacctg
    14041 ttctgaagct agtggcgaga aaatatctcc tcctatgatc acattttgaa aatcaacata
    14101 agaagttggc aagtaatgac tgattgattc tatccatcca atcgaagaaa acaagcgata
    14161 ctctgctaag aaaagacaaa gaagtgtacc taaaagattg actagagaat gttcaaataa
    14221 agcagataga agaaaactga ttgtacttaa aaagagcacc cacaacaaca ggaacagaaa
    14281 gctctggaaa agatactcat acatcggcag gattcgtatc tcctgaccaa tgatcgttcc
    14341 tacaggataa cggaagtctc ccaaaccatt tttgattatt actagtatag agacgatcaa
    14401 aaatggcatc acgagactta gcatagctgc accataataa atggtaaaac ggatgctatg
    14461 tttctttacc atactatccg gtaatagatt gactagagag attacctgct ttcttttttc
    14521 ataagagatg atggaagaaa gaaacaaggc ggttatacat aaaatcaaaa aactagaaat
    14581 cattcctgaa aaaatatttt cgtagtaatt tgctaaagag agatgcgctg gcaagtcaaa
    14641 aatagaatat ctttggatct gatgttcttt catataacgg agcaactcga cacgtttttg
    14701 ttgttcaatg attggaattc cttgtctttg accagaaatc agtcgatcca gtatatcttt
    14761 ttcataatga taagttgctt cgaccatttg ctggacattc cctgtgtttt ttgcatgtaa
    14821 gattgcttcg atcagtttgt tgcttttctc taaactttcc acaaattctt tctcattctc
    14881 atcttctttc aacgtttcaa tcaaacgttg catctcttca tagttatgat tcagttcatc
    14941 gaattctgta taagcaagtt tatgatcaaa aaaaagtggg aatgcaaaga gcacgaccaa
    15001 caatagagga aataaaaagt ttactttgtt ttttagtaag agattgcgtt caaatgtaag
    15061 taaagacata gttacacctc atataattta cgataaatag ctaaaatctc ttccatattt
    15121 gaggattctg tgacgatttc tccatttttt agaaaacatg ctttagaaca aatcgattgg
    15181 atattcgcga tagcgtggga agaaagaaga atcgtcttcc cctctttctg ccattgtctg
    15241 atgaggctat tcaagatatc aatacttcct gggtctaatc cgttcaacgg ttcatcgaat
    15301 aacatgacag atgaatcact gatcaagtaa gcagcaagca agacatgttg tttcattcct
    15361 agagacattt ttccaatcgg caaagtaagg tactcagtca tcttcaatcg ttggaaaaca
    15421 gtttggcatt ctactttgct ctgccaatag tatttgatca aagtcaaata atcaacagcc
    15481 gatagatagt cggataactg attcgttgat tctagaaaaa agaaagaccg gcgataatct
    15541 gtataagcag taggagagat gttgtgaagg gacaattgat cataagttgt tggcagcagt
    15601 tgggcaatgc cattcagcaa agttgttttg ccaaatccgt tcggggcaat caaagcagct
    15661 acttctcctg attctactaa aagattcaat tgtcgaatca cacgtttttt accacgtttc
    15721 atgttcatgt ttttgatcag taatgtcata gataggcctc caatataaaa tttaataaca
    15781 taatagaatg gaaaacatct aaattaaatg ctaacaaaag ttattgtttg catattataa
    15841 aaaaattaaa ataacagttt tatttaaaat tgaagttttc tgataccgaa atctttttat
    15901 tttgctgaca tactcaaacc tttggcacaa agtttcgtgc caaagtacga ctatttctct
    15961 ttttagtaag cggatacaat tagagtatca aaaggagaga gggagagaca aaatggaacg
    16021 gacgattccc aaaaacaaca tttcgctaaa agcgagggta caaaaattag gcagtacttt
    16081 atcaagcatg gtcatgccaa atattggagc actgattgcc tggggtgtat taacggctct
    16141 atttatccca gatggttatt taccaaatga ggctttcgct accatggtaa gcccaatgct
    16201 aacttatctg attcctttat tgatcggtta tactggcgga aaagtaattg ctggtgaccg
    16261 cggatcagtt gttggggcaa ttgcaacgat gggtgtgatt gtcggaacag atattccaat
    16321 gatgctaggc gcgatgatca tgggacctct tggtggatat gccatcaaga aatttgatca
    16381 gctattccaa aaacggatca aatccggttt tgaaatgcta gtcaataatt tttcagcagg
    16441 tcttatcggt tttggattag cgttattagg tttttctgcg attggtccag ttgtcgatgc
    16501 attgactcaa gcaatggcaa aaggtgtaga gatcatttta tctgcccatt tgattccatt
    16561 gacaagtatt tttattgaac cagcaaaaat cttatttttg aataatgcaa tcaatcatgg
    16621 gattttgaca ccattgggaa ctgaacaagt agcagaggct ggaaaatcta ttctattctt
    16681 gcttgaagca aatcctggtc caggacttgg cgtattactt gcttttactt tgtttggcaa
    16741 aggagcagca aaatcttcag caccaggagc catgatcatt cactttttag gcgggatcca
    16801 tgaaatctat tttccttacg ttatgatgaa accgttatta ttcttatcag ttataggcgg
    16861 aggaatgtca ggaagtttca ttttccaatt gatggatgct ggactaagag cgccagcttc
    16921 tccagggtcg atcattgcga ttctagcgat gacaccgttc aattcttacc ttcctgttat
    16981 tttgggcgtg attgttgccg cagctgtttc gtttggtatt tctgcagtaa ttttgaaagc
    17041 ggatgcgaaa gatacaaatg aagacttcga aaaatctgtt caagagacaa aggcagctaa
    17101 gcaagcttcc aaaggtgccc aaggtattcc tcaaggagct acattctctg gcgtacaaaa
    17161 aatcattttt gcttgtgatg caggaatggg atcaagtgcg atgggcgctt cgatcttgag
    17221 aaaaaaagta caggaagcag acttgcctca aacggtgacc aatcaagcaa tcagccaact
    17281 gacagatgac tcgaatacat tgatcgttac tcaggtcgaa ctacaagaaa gagcaaaaca
    17341 aaaagcaccg agcgcgcgtt ttgtctcagt agaaaacttt ttgaattcac ctcgatatga
    17401 tgaaatcatt caagaattaa gcagcaagca gaaaacatca gtttctgaaa ttgagaatga
    17461 gccagcagaa gagtttcttt cagcaaacat caaacaaatc aaagagattc tacttgtcca
    17521 cgatgatcgt tccggatcag caacaatggg gatgaccgtg ctcaaagata tattagacaa
    17581 gaaccattta actatcccgt taagaaaagt caatatccaa gatttaaaag atgaacctga
    17641 ttcactgatc gtagccaaag aaagtttagc ggaaaaagta cagatggctg cacctcaatc
    17701 cattcattta tcagtcaaca gcatggtcaa tccgcaaaaa tacgaatcga ttgcacaata
    17761 tttgaaacag acagcttaag ggaggaaaac agcatgcaaa gtttgccatt cgacatgatc
    17821 gagctcaatc gatcttttaa aaccaaagaa gaagcgatcc gctattgcgg tcagatgctt
    17881 gtagaagcag ggtgcgttga tgaggaatat atcgatgcca tggtagatag agacaaaatg
    17941 ttatctgttt atatggggaa ttttatcgcg attcctcatg gaacagatga agcaaaaaaa
    18001 tatgtgaaaa aatccggcat ctgtgtcgtt caagtaccag atggtgtaga ttttggtacc
    18061 gaagaagaag aaaagattgc gactgttttg ttcggtattg caggagtcgg agatgagcat
    18121 ttgcaacttg tacagcaaat cgcactttat tgcagtgata tggacaatgt tgtccagcta
    18181 gcagacgcgc tcagcaaaga agaagtaacg gaaaatctag caattgctta aggagagaga
    18241 aaaatgagag cagtacattt tggtgcagga aatatcggtc gaggatttat tggagaggtt
    18301 ttggcagcta atggatttga gattactttc gtagatgtga atcacacgat cattgatgct
    18361 ttaaatgaaa gaaaagaata cgaaatcgaa ttagcagatg aatcaaaaga aaaaatcact
    18421 gtaaaaaatg tcaaaggaat caacaatcaa acaaatccag aaaaagtaat ccaagaaatc
    18481 gctgaagcag atttagttac taccgccatt ggcccgaata tcttaccttt tattgctgag
    18541 ttgattgcaa aaggtatcca agaaagagaa aaggaaggaa gcacaacatc tttagatatc
    18601 attgcctgtg aaaatatgat tggcggttca gcatttctag aaaaagaagt gtataaatat
    18661 cttccggaaa catcatttac tgacaaatat atcggctttc caaatgcagc agtcgatcga
    18721 atcgtcccat tacaacacca tgaagatcct ttattcgtcc aagtggaacc tttcaaagaa
    18781 tgggtcattg acgatagcca aagaaaaaat aaaaaaatcc aattaaaagg ggttttatat
    18841 gtagatgatc tagaaccata tatcgaacgc aaactattta gtgtcaatac tggtcatgcg
    18901 actgtcgctt atacaggtgc cttgttaggt taccagacca ttgatgaagc aatgcaagat
    18961 gcgttagttg tggcacaatt aaaatcagtt ttgcaggaaa caggaagttt gctgattgcc
    19021 aaatgggggt ttgatgcaga gcagcatcat gcgtatattg aaaaaatcat tcatcgcttc
    19081 caaaacaaaa atatctctga tgcgatcaca cgtgtcgctc ggacaccatt acgtaagtta
    19141 ggttatcaag aaagatttac acgtccagtg agagaactac aagaacataa cttgacttgc
    19201 ccacatttga cggcaacaat ggggattatt tttaattact atgatcctga agatgaacaa
    19261 agccgtcaat tgcatgaaat gaagatccat gaaaacttgg aacaattgat tcaagaagtc
    19321 acaggaatca atgatccgaa aacaatcggg aatatcaagc aaaacgtgaa ccgttatgcc
    19381 aagcaagtcg cttaaaatag gatacgaaaa aggggaatgt gacgaaattt ttgtcacatt
    19441 cccctttttc gaataactag gctgtttgtc cttcaagata gggcagatcc aattctttac
    19501 cgtaacgttg ttctaaagct aggcggatca aacgagctgc caggttctca tttcttgcaa
    19561 ggataggtcc atggaaataa gaaccgaaga catttcggta aatgacacct tcagattggt
    19621 cttcaccatt atttccttga ccttgtacca ctttccccaa aggtcgttca ccttcaccta
    19681 agaaagtccg accattgtgg ttttcaaatc cataataagt ttcattgaat tcttcgttat
    19741 ggataacgat atcaccgata aaccggttat tttcctgact taacgtgtag tgatccagtg
    19801 cactgattcc ttggatcttt tctccattag ctcccatgta gtagtgacct agcaattggt
    19861 agccaccaca aatggctaac atgacgccat cattttcgat atagttgatc aaagaatctt
    19921 tctttttctg gatgtctttt gaaatgatta attgctcaaa gtcttgacca ccgccaaaga
    19981 aaaccaagtc atatttatca gcatcaaaag gttcatgtat actaacgatc tccgtatggc
    20041 aagaaacccc cattttttct gctatatatt tcaacatcaa aaggtttccg ttatcaccat
    20101 atgtgttcat caaatttcca taaaggtggg cgatattgag ttcataatta gccacggttc
    20161 attcctcctt tgataaatcc ttgagcagct agttctttac gaagctgcaa tacagcagtg
    20221 taagtagcta aaatatagac atgctcagtt ggcaattctt tgattttttc gattacttct
    20281 ggtaattctt ttgtttctgt caatttattt tctggaatcc cggcaacttt tagacgtaaa
    20341 gtcatatctg tatgacggtc tcctccagaa ataacagctg ggatatccat atcggcaaag
    20401 ttttcaaaat taccatccca aatccagctg acatcgattc cgtctgcgta attggcattt
    20461 aataaagcca ctaaagaaaa tggataagga gctagaccaa tcatatcgat tacttgattg
    20521 atacctacag gatttttgac aagtactaat gtacattttt tcccattgat attgatgact
    20581 tcttgtcggc cgaatacttt ctcgtcatat cctaaacctt gtttgatttt atcaggatcg
    20641 acattgaagt actctgccac tgcagtagct gctaaagcat tgtagacatt atacataccg
    20701 ccaacttcga ttccgtattc atgaccatcg atcacgaaat ctgctgacac attgtccatc
    20761 cgtaccatat cagttaatcg ataatccaat tcaggacgtt tgaagtcaca atttggacag
    20821 taatatttcc ctaagtttgc ataagtgatc attttataat gcaagatgtg atgacaattt
    20881 ggacataaga caccgtctgt attgtaatga gccatttgtt cacgatcttc ttcatggtca
    20941 aagccataat attttctagg attgactgtt tcgatagaat tgaagattgg tgaatcaccg
    21001 ttactgataa tcgttgcatt tggtgacttt gcggcaccgt ctacaatcat tttataggtc
    21061 gtatagattt ctccataccg atccatttga tcacggaaaa tatttgtaaa taagaacagt
    21121 tctggtttca tatattctgt gactttgctc aaacttgctt catctatttc taggacagca
    21181 aactttttct gtcctttttt tggttttgcc tgcaagaaag tcgatacaat tccctgtacc
    21241 atattcgcac cagtagggtt ggttagaact tcatcgaatt gctggcgcaa aatattgact
    21301 gttaaagcgg tagtcaatgt tttaccgttt gttccggtga caacgacgac ttggtagtct
    21361 tttgccaaac tatctagtat atgtggatcg actttcagcg ctagtttacc tggtaaactt
    21421 gatccgcctt taaaaaaagt ttttaatgcc cattgcgacg tttttccaac tgcaatcgca
    21481 aaatgactgc gtattcccat tatgtaacct ccaaaaacga tttgctgacg aataaattca
    21541 actaatcata ccatatgttg aaaaaaaggt taaattgctt ttcttattct taagaaaagg
    21601 ttacggctga aagtgcatga aatcggacaa aatcgcatga tttaacaaaa aaacagcttg
    21661 aaacaaaatg attgtttcaa gctgctgtga ttttattatt ccctcttacc tatattccca
    21721 ttttaaccga taataatttt ctcgcttgga tattcatagc ctagatctcg tgtttctttt
    21781 ggcacgaata acatcaatgt atatagcatt ccgatccgcc caataaacat cagtgtagca
    21841 atcgtgattt tgcccacaac agacaagtct ccggtaatcc ctaaagataa accagttgtt
    21901 ccaaacgcag aagttacttc gatgatgatc gagatcagcg tttgttcttc tgtagcagat
    21961 aaaaaaacga tacaaaagaa acacatacca agagaaagca taaagacaac gactgatttt
    22021 cgcacatcat cttgatcgat tctccgtcca aaaatattga tgttatcttc acttttgagg
    22081 aaggaatata gatacaaacc gatgattgct acagtagttg ttcgaatccc gccgcctaca
    22141 gaactaggac tgcatccgat aaacatcagt aaagaaaaaa tgatcagtgt tgtgatttga
    22201 aaatcaccca aatcgtgaat ctgcagacca gcattacgag tcgtaatcga ataaaacatc
    22261 gaattgatcc atttgacact catattggaa tcttggaata aatggtcctt ttccaataga
    22321 taaatcaaga cagttcccga aacaaacaag ataacaaaag ctaacacagc taatttggta
    22381 aacaaggaaa aacgaaacgg aagcttcgca ttggaacgtt tgtataatag ccattcccgg
    22441 cactccatca atacaggaaa accaattcct ccgacaaaaa tcaaaaacat gatcaggatc
    22501 aagaaaaaat agtcatgtgc aaagggcttg atggaatccc cagtgacgtc aaacccagag
    22561 ttcgtgacag ccgatatcgc ctgataaaaa ccgtaaaaaa cggcatcacg ccaacgatca
    22621 aaatagcctc tgtaataaaa ataaatagaa aagaatgtcc caaaaagtaa ttgaaaccag
    22681 attaaaatag caaaagtgat ccgaatcagt cggacgatac cagacaaacg cggttgattc
    22741 atatccgtca tgatcagctg tcgctgtttc agtgtgatcc gtcgtttaga aaaaatgaca
    22801 aaagcagtag aaatcatcat gatccccaaa ccaccaactt gaaataatat ttccagcagt
    22861 ataataccgt tatcattgaa cacagaattg atatcaaaag tcgatagtcc agtcacactc
    22921 actgtactga ttgccatgaa cagcatgtcc acaaaagaaa catggctatc tggttcgcga
    22981 aaaatcggca tataaaatag aacgagtgat aagaccgtca tcaatatata ataaaaaacg
    23041 atgatttgga tcgatgagaa atgattggca gcaaacttct gtcctcgccg ctgcagcctt
    23101 cgaaagaata aatcaacatg cacagtacta tcctcctgac aatagtcgtt tctaccagta
    23161 tacaagggga attaggaata ctcaaagaaa ttatcaaaca gataacaata cagctttcga
    23221 ttaaaataga aatggcttat aataaggaaa atcctagaaa aaagaaggag gaggaataac
    23281 aaattgatta atgctcaaca aatcgtagaa aaaatgaaaa atcaaaaaat aaattatgat
    23341 acagttctga aaaaaatgat catgcaatgg gagaaagaag aagtaaagcc taagatatta
    23401 atacatacat gctgtgctcc ttgcagtacg cacacattgg aattcatgtc tcaatatgca
    23461 gagatcacgt tatttttttc aaattcgaat attcatccta aaagtgagta tttgcgaaga
    23521 ttacatgaac aaaaacgatt tgtagaccaa tttaatgaga aaactgacca tcatgttgcg
    23581 ctaatcgttg atgaataccg tccaaatgaa ttcaccaaaa tggttttaac aaaccatctt
    23641 gaaaacgaaa aagaaggtgg tgctcgctgc agtgcatgct tcaatatgcg attagatctt
    23701 gttgcgcaaa aagcgcaaga actaggatac gattactttg gaagtgccct gaccatctcg
    23761 ccaaagaaaa atgcagcttt gatcaatcag atcggaatgg atatccaaaa gatttacggg
    23821 acacaatact tgccaagtga tttcaagaaa aacaaaggct atgaacgctc tttgcaaatg
    23881 tgcaaagagt atgatattta tcgccaatgt tattgtggtt gcgtgttcgc tgccaagcag
    23941 caaggatgcg atctgaaaga aatcaatcgg gaagcaaaag cttacttaaa aacatcaacc
    24001 gtagtttttg aggaaaatta aagaaatctt tcggaaaaac gtaagaaaaa aataaagaat
    24061 ttatggtaga aataaggtag actgtataat ttgtccgtag taaagtaagg aaacaagaat
    24121 aaatttcaat gaaggaagag ataagatgcg aaaagtagca cctattttga agccaatcgc
    24181 tgtattaaca atctcgacga ttgtcgcgac tactacaggt attgtgaata gttccagcta
    24241 ccgtgcacca agttcaagtt ctagtactgt agaagaaaca acaccaacta cttcagtctc
    24301 gacatctgaa ccaacaacaa cggaaagttt gaatgaaacc actacgacaa gtacatggga
    24361 cgatacaaca actagttcgt cgtatgatga gacatataca actgacagct caagcgaaac
    24421 aagtaatacg gtaccagatg gcactccatc ggattcaacc aatccaagta caagtccgga
    24481 tacaagtgct agctccgaaa cgataccaag cagtacgact gtagatgata acacgcaaaa
    24541 tgatgatgca gcacgtacag cacagcaaaa ccaagattca ggaaataccc aaacgtataa
    24601 ccagcaagca ggtgattctc aatgacattt ttactagacc ttatcaacgg ggtgcataaa
    24661 ttccttggct atttagacat cagtcctaaa tatcttaacc gtggatatac gattttaagt
    24721 gtgattccca cgctttattt attgagaatt gtttatggac tttggcaaaa ccaaaactat
    24781 cttcaatttt tcttatatgg acttgcattt ctagtgcttg tttattttac tgttttaaat
    24841 gtattttatt actttttaga taaaaacacg aaagccgatg tcactcagct ttttgtgaag
    24901 tatttacctg atgaagcgtt caacatccag acagaagaat cgatagataa tggaaattcg
    24961 atcgataaag tgaatacaca agaggtcatg gtttcttatg acgaagatta tcaattgaaa
    25021 ttagccgaga atatgcggta tttgattgga aatggtgaga tcaaaacaaa tgaactcggt
    25081 cgcatggatg gatttctggt cgatagaaat acattgtatc cttattacta tgtcaagaaa
    25141 acaggagaga aagagtatgt tctaaatatt ggacgaagct actcggacat ggaaaaagta
    25201 gggaccattc gacttgactc aacagaagac acattggaac ctgtcggatt gttcatcgtc
    25261 ggcggtgatt ttgtcaaaga cgggttacgc tatcatgagc cttatcgtct gaaattgatt
    25321 gcaaaaaagg cacagtcgca ggaagaacca gtggtttata gtcgtagcca aagaagaaga
    25381 cattcataat gtgatgaaac gccgtgtatc agtggttgcg ataaaaacgt ttattcggaa
    25441 taagggggat gtgacacgtc ttttgtcacg ttcctttttt atataacgag aaagataaga
    25501 cgaacacatc acttattctt tcctttcatt tataaacatt gtagaataaa gaaagtacaa
    25561 cgaagtattg tgaaaaaacg taataaataa cgaggaaaat acaagtagga ggtaagctgt
    25621 gaaagaattt ttgaaaaatt gggggatttt gatccttgta ttagcggcta ttttattagc
    25681 tagagtgtac gtgtttacac cagttactgt aaacgggcat tcgatggacc ctacattaag
    25741 tgatggacaa cgattgattt catctaagat ctcaaactat gaacgaatgg atattattac
    25801 tacaaaggaa ccgggggatg aagaacggat gattgttaaa cggatcatcg gtatgcctgg
    25861 agatacagtc aagatggaaa atgaccagtt gaccattaat ggcaaaaagt atgatgaacc
    25921 ttatctggat gagttcaaaa aagaattttc agaagataag ttacaaggag aatatgctta
    25981 tagctcagga ttccaagcac aagcagaaag ttcatccacc tttacgagtg actttgaata
    26041 tactgtgcca aaaggaaagt atcttgttct aggcgataac cgcttgattt caaaagacag
    26101 ccgaatgttt gggttagtcg acaaagatat gatccaagga aaagttgttt tccgttattg
    26161 gcctctttca gaaattaaaa tcatgtgatg aaaaaataaa aagaagctgt gacatgtttt
    26221 ttgtcacagc ttctttttcc gaaaattcct tcttatttct tggagttgct cacttttttt
    26281 gcaatctcat tttaagcttt ttggctgatg gataagaaaa gcgaagcgtt tttgttcata
    26341 aatagctttt ccccacgatg gaaggtatga ctagtagcag agacaaagcc cgttttttcc
    26401 aatcgattat tcaattcttc ttggctaaag ccattatgga ctttcggatg actaatttgt
    26461 tcattcttgt caaagtctac gatgatcaat tgaccgccag gagctaaaat ttcataaagt
    26521 tttgtaagaa tattctccgt atcaggaatg tgtaaaagta caagtgatag aaggatgaga
    26581 ttagcttgga cagcaggaaa ttcgacagaa gcatcagcgt ggatcgttcg gacatttttc
    26641 agatctgctg cttggatctt ttcttctgcc attttcagca tagtttctga agcatcggca
    26701 atgatcagtt ctttgaatct ttccgcaagc ggtaaactaa caagcccagt tccgcctccg
    26761 taatccagca ggactttttg gtggctgtcg cgcggtagat aagtagttag ttcttcgcga
    26821 ataatcttgg ctaatgcttg acggtcaggg gaatcataat ggttagcgat ggaatcaaaa
    26881 atattttttg tcatcaaata gctccttacg taaaactttg aaattttaac ttattatagc
    26941 acgtgaaaag aaagaaagca tgctatactc aattcaaaaa gggagaatct agaaagaata
    27001 tgccgatatc gtttgtaaaa gatagagagg aaaaaggaaa gtgtgtccga gaaatattac
    27061 tagacttgcc tgagtggttt gggcttcctg aatcaacgga aaaatatatc gaggaatcaa
    27121 gtaaactacc tttatggtgt gaaaaaagaa aagaagaata tttaggcttt atcactcttt
    27181 cacagacaag tgaagatact gccgaaatct attctattgt atgggaataa aaaaagacta
    27241 tcatcaccaa ggattaggaa caaaactttt taaagaagca gaaggttacg cagcaaaaca
    27301 ttacaaatat ttgcaagtga agactgtaga cgaggggcac tactctatat atgatcaaac
    27361 tatttgtttc tacgaatcat taggattttc aaggttggaa gtttttccaa atttatggga
    27421 tgaatggaac ccatgtttag ttcttgtcaa aaaattggaa caaaagtgag caatagattt
    27481 aatactaatc tgtgcttgat gaaaattctc actgtaaaaa atgctgaaaa tcaagtataa
    27541 taccatagga acaaactgga aggtgaaaaa gagcatggca caactatttt ttaagtatgg
    27601 cgcaatgaat agcggcaaga cgatcgagat cctaaaagtc gcacataatt atgaagaaca
    27661 aaataagcca gttgtcttaa tgacaagcgg tattgataca agagatggtt taggcgttgt
    27721 ttcaagccga atcggactga aacgtaatgc gatgccgata tttgaagaaa cagacgtatt
    27781 tgacgtaatt cagaaaatgg aaagcaaacc ctattgtgtg ctgatcgatg aagcgcaatt
    27841 cttaaaaaag aaacatgtca ttgcttttac gagaattgtg gacgaattgg atattccggt
    27901 tatggcattt ggtttgaaaa atgattttcg aaacgagtta tttgaaggat caaaatattt
    27961 attgctttat gcagacaaaa tcgaagaaat gaaaacaatc tgttggttct gccacaaaaa
    28021 agcaatcatg aatttacatt atattgatgg aaaccctgtt tatgaaggcg atcaagtgca
    28081 aattggcgga aatgaagctt attaccccgt ttgtcgaaaa cattactttc acccatcaat
    28141 gattacagaa ggagaataag catgtacgat caattacaag caattgaaga ccgttatgaa
    28201 gagcttggag aacttttaag tgacccagaa gtgatttctg atacaaagcg ttttatgcag
    28261 ctttcaaaag aagaagcaaa cacgcgcgaa acagtcgaag tttatcgtcg ttataaagaa
    28321 gtagtacaag gaatcaccga tacagaagaa ctgcttggtg aaaaactgga tgatgaaatg
    28381 gctgaactag caaaagaaga attatctgaa ttaaaaaaag aaaaagaagt cttagaagaa
    28441 aaaatcaaga tcttgctttt accaaaagat ccaaatgacg ataaaaatat catcatggaa
    28501 atccgtggag cagcaggcgg agacgaagca gcattattcg ctggcgatct tttcaatatg
    28561 taccaaaagt atgctgaagc acaaggctgg aaaacagaag tgatggaagc taacgttacc
    28621 ggaatcggtg gatataaaga agtgatcatg atgatcaccg gagacaacgt atattcgaaa
    28681 ttaaaatatg aaagtggtgc gcaccgcgtc cagcgtgttc cttcaactga atcgcaaggg
    28741 cgtatccata cttccaccgc aacagttgtc gtgatgccag aagctgaaga agtagagatc
    28801 gatattgaag acaaagatat ccgtacagat atctatcatg cttcaggtgc tggcggacag
    28861 cacgtcaata aaacagcatc tgctgtacgt ttgactcact taccaacagg gatcgttgtt
    28921 gctatgcaag atgaacgttc tcaaatcaag aaccgtgaaa aagcaatgaa aatcttgcgt
    28981 gctcgtgtgt acgataagat ccagcaagaa gcacaaagcg agtatgatgc caatcgaaaa
    29041 tcagcagtcg gaactgggga tcgttcagaa cggatccgga cgtataattt cccgcaaaat
    29101 cgtgtgactg atcatcgtat cggattaact atccaaaaat tagatcagat tttagcaggg
    29161 aaattagatg agatcgttga tgcattgatc atgtatgatc aaacatcaaa actggaagct
    29221 atgcaaaatg ggtaaaatga cctatcgaga agtcctgtca cgggcttctt cttttttaga
    29281 ggatcatggg aaagaagcat atagtatcca atttttattt ttggaacgaa aacaatggaa
    29341 aaaacttgat tggctccttc atatgaacga agagatttca gaagaagaac agcggttgat
    29401 cgaaaccgat ctgcgacttc tgcttgcaga tcatccacct cagtatttgc taggatatgc
    29461 agatttttat gatcatcggt taaaggtaac tgaagcaaca ctgatccctc gaccagaaac
    29521 agaggagtta gtcgaatggt gtttagacga gacgcctggt gtaccgttag aagtgataga
    29581 tattgggaca gggactggag caattgctat tagtttgaaa gcagcaagaa aaaattggca
    29641 tatatctgct gtggatcttt cagaagaagc attagaagta gcgaaagaaa atgctcagaa
    29701 agaaggaacg aaaatcagtt tttatcatgg agatacatta ggaccagtaa tggatcagca
    29761 atttgatgtg attatttcta atccgccgta catcagtcgg aatgaatggg aactgatgga
    29821 tgaaagtgtc cggtcattcg aacctaaaat ggcccttttt gctgagaacg atggattagc
    29881 tatttatgaa aaaatagcag ttgaagcacc aagcgtacta aaatcaaatg gaaagatttt
    29941 tttagaaatc ggatttcgcc aaggtgaagc agtaaaaaaa atatttcagc aagcatttcc
    30001 agataaaaaa gtggcgataa aaaaggatct ttttggcaat gaacgaatga tccaagttta
    30061 tggttgaagt tgtggatgaa aaatttttta tttgtttttt tattataaaa aaacacttat
    30121 ttgacaagga tgtaaacgac tttttggttt atcaacaagt ttatccacta ttgacaaata
    30181 gattatccac aaacagtgga aaacttgagg ataaactcag acaaaataag aatgtatgaa
    30241 aaaggggttg tggataaact gtggaaacga aacgatatga tgaaacagaa ttgcaagagg
    30301 cagccgaagc actgaaagaa ggagaacttg ttgcttttcc taccgaaaca gtatacggat
    30361 tgggcgccaa cgctctttta ccaaacgctg tcaagaaagt gttttctgta aaagggagac
    30421 cgcaagataa tccattaatc gtccatgtcg cctcttttga acaagtaaaa gagtatgtgg
    30481 acaactttca tccggcagca gagaagattg tgaagaactt ctggcctgga ccattaactt
    30541 tgatatttaa gatcaaaaaa gacactttgc cctcagttgt gacgggagga ttatccacag
    30601 ctgcatttcg tataccggat aacaaaaaaa cactagaagt aatcgaactt tccggtgttc
    30661 cgcttgtcgg tccaagtgca aatacgtcgg gaaaaccaag tccaacgact gcagatcatg
    30721 tatatcatga tctacaagga aaaattaccg ggattattga tgatggagct acgcgaattg
    30781 gtgtagaatc cactgttctt gatttaagtg atccaacagc catgcctatg attttacgac
    30841 caggtgcagt aacgaaagaa caaatcgaag cagtcatcga atctcctgtt gctattgatc
    30901 agcatcttgt aaaagaaaat gaaacaccaa aagcccctgg gatgaaatac aaacactact
    30961 cacccgatac acgtgttctg atggtcagag atggcgattg gtcaactgca gttcaatggg
    31021 caaaaaataa gaagatccgt gcaggtgtca tagcaagccc cgaaattgcg gatcaagtgc
    31081 ggacagatac tgcagctgtt tatatgtata acgacaactc agtagaagcg gcggctaaag
    31141 gattgtttgc aggtctaaga ggattagatg aaccaacact tggattagat ttgatttttg
    31201 tacaagtgta tccagaaact ggattgggga atgcttacat gaatcgcttg aaaaaagcag
    31261 caggacaaaa ttattttgaa aaatgatcaa ttggttattg tcgcattctt ttagtatgat
    31321 acaatgctat caagtaaatc ttctatcagt gaacgaaaaa ctaagcgtaa ctaatcgtaa
    31381 tagaagagat acgaatattt ggcaatttgt ttttgatggg aaaaataaaa ttgtaggaaa
    31441 ataaaaagga gctgttgttt gtggtagatt acaaaacgtt tgaccctgat ctttgggctg
    31501 cgatcgccaa agaagaagaa agacaagaac ataatttgga gctgattgcc tctgaaaact
    31561 ttgtctccga agcagtgatg gctgcacaag gaagtatctt gacaaataaa tacgcagaag
    31621 gttatccagg gcatcgctat tatggtgggt gtgaatttgt cgatatcgtt gaaaatttag
    31681 cgattgaccg tgcaaaagaa ttattcggag cgaaatttgc gaacgtccag cctcactccg
    31741 gctctcaagc caacacggct gcttatctcg ctttggtaga accaggggac acgatcttag
    31801 gaatggatct ttccgcaggc ggacatctaa cacatggatc accagtcaac ttcagtggca
    31861 aaacctatca ctttgttgct tacggtgttg atccgacaac agaagttatt gattataatg
    31921 tggtacgtat tttagctaga aaacatcaac caaaattgat cgtagcaggt gccagtgctt
    31981 acggacgaac gatcgacttt gcgaaattca gagaaatcgc agatgaagta ggcgcaaaac
    32041 tgatggtaga tatggcacat atcgcaggat tagtagcagc aggacttcat cctaatccag
    32101 ttccttatgc agatatcaca acgactacca ctcataaaac attgcgtggc cctcgaggcg
    32161 gcatgatttt gacaaacgat gaagcattag caaaaaaaat aaatagtgcg gtatttcctg
    32221 gtattcaagg cggccctcta gagcatgtga ttgcgggtaa agcagtagca ttcaaagaag
    32281 cattagatcc tgcatttaaa gaatatagtg aacaaatcat cgccaatgca aaagcaatgg
    32341 tcaaagtttt caatcaagca attggaacca gagtcatttc aggggcgaca gataatcatc
    32401 tgatgttgat cgatgttcgc gagttaggta taaatggaaa agaagcagag agcattttgg
    32461 acagtgtgaa tatcactgta aataaaaact cgattccttt tgaaacacta agtccattca
    32521 aaacaagcgg tattcgaatc ggcacgccag caatcactac tcgcgggttc aaagaagaag
    32581 atgctgtaaa agtggctgaa ctagttgtca aagcattaca agcaaaagat gataacgctc
    32641 aactagacga agtcaaaaca ggtgtacgcg aattaactga aaaatttccg ttgcataaaa
    32701 aataaaaatt taaattccat tagtaaacag aaaagttcaa tgttgggctt ttctgtttat
    32761 tttttgggaa aacggattct ttgacaatat cggtgatgct ctctagtata tgaggtgtaa
    32821 ttttagtctt cacactaaat ctcagggagg aaaagtcatg actgatcgta tctcgttaga
    32881 aaaggaagca gtagcattca gtgatgcaaa tgcgcctcat ccgcgtatct atgaactagc
    32941 accggaagaa ggaagagttt tactagaaga agtacaagaa tcacctgtga acaaatattc
    33001 cgtcgatatt gaagacttga tggtggatac tggcgaatgg ggaaaactca atattcgtct
    33061 cgtacgacca gaagggaata tggataaatt accagttatt ttttatattc atggagcagg
    33121 ctgggttttt ggcagtgctc aaacccatga taaattgatc agagaacttg cggttcgtac
    33181 gaattccgtc gttgtctttc cagaatatag tcgatcacca gaagcaaaat atccaacagc
    33241 aattgaacaa aattatgctg tgttgcaaca gctgaataaa ttagccaagt caaaaaatct
    33301 ggatctcgag aatctaatcg ttgcaggaga ttcagtaggt ggtaacatgg ctacagtcat
    33361 gacgatctta acaaaagaac gaaagggcct cccaatatcc aagcaattgc tgtattatcc
    33421 agtcacaaac gctgattttg atacagattc ctatcatgaa ttcggagaaa actatttttt
    33481 gacaagagaa ggaatgatgt ggttttggga ccaatatacg acgaatgaag aagagcgtgc
    33541 tgaaatcaca gcttcgcctt tgagagcaaa tataaatgaa ctaaatgatc ttccttcagc
    33601 aatgatttta acgggagaag cggatgtatt aagagatgaa ggtgaggctt atgcgcgcaa
    33661 acttcgtgat gcaggggttc ctgttacaca agtacgcttc caaggaatca tccatgattt
    33721 tgtcatggta aatgctatgg atcagacaaa ggcaacgcgt gcagcaatgg cattatctac
    33781 ttcttggatc aagaaaaaag aataagcttt gcttgtccgc aggaaaactt cttttcaaaa
    33841 acggattttc ttaggaaaaa tggcgagttt gactagtcaa tcacttgatt ttgttttaca
    33901 attaaaaaga aacgacagaa caaaggagag cttaaaaaat gggcaaattt caagtgatcg
    33961 atcatccatt gattcaacac aaactaacta ttattcggga caaaaactgc ggaacaaagg
    34021 tttttcgtga agtagtcgat gaaatcgcta tgttgatggc atatgaagta tcacgggata
    34081 tgccattgga agacatcgtg atcgaaacac cgatcactga aacaacacaa aaaacgttgt
    34141 ctggtaaaaa agtagcgatt attccaatct tgcgcgcagg tattggaatg gttgacggta
    34201 tcttggaatt gattccagct gctaaagtgg gacatatcgg tctttatcga gatgaagaaa
    34261 cattggaacc acatgaatat ttcgtcaaac ttccagaaga cattgatgca cgtcagttgt
    34321 ttgtagtaga tccaatgttg gcaacaggcg gatcagcaat catggcaatc gatgcattga
    34381 aagaacgtgg cgcgtcgaac attaaatttg tttgtttggt agcagcacct gagggagtaa
    34441 aagctttgca agaagcgcat cctgatattg acatctatac agcttctcta gatgaaaaat
    34501 tgaatgaaca tggttatatc gttcctggac taggggatgc gggtgaccgt ttgtttggta
    34561 caaaataagt aaatacgaaa aagggtgtga cacaactttt gtcacatcct tttttggtca
    34621 tttttaacgt ttgatgcaga acagcttttt cacagctttc gtttgcatat aaaaaaacca
    34681 tcccaaaaat gcagagatgg tcaaattcaa atctttttta gttctttgta gttaacgatt
    34741 actacaccct tactttgcgt catcaagttc gcattttctg cagtttcatc aatctcaaca
    34801 acagcggaat ttttcaattg ctttgaaatc gttccagttt gcgacttgcc gtgaattgtg
    34861 aacattacgt gagtattgat cttgaatttt tcaccaattt ccgatggtac gatagttgta
    34921 tcaaattttc caaaagttgc cattttcata aaacctgcct ttcacatcaa ttataccacg
    34981 ttttatgaaa aatatcatga aattaaacta attttccatc ggactcttta caatcagcca
    35041 aatagagtat ataatttctt ttggataagg ccagcttagc tcagttggta gagcaacgca
    35101 ctcgtaacgc gtaggtcgta ggttcgatcc ctatagctgg cattaaaaga gaagacagat
    35161 atatcaagga tttttaatcc attgatacat ctgtcttttt gtttaaagga aataaagtat
    35221 gctttcttag caatagagca tgtattattt ctataaaaat ttaggagaat aaaacgacta
    35281 gcaatatagc tgtgaaatca aatatcacat gaactgccca acttgtaatg atcgagttgc
    35341 ttttaatggc agcttggttg aataacaatc ttgccacccc ttgtatcaaa aggatgtgtg
    35401 ctacagtgtg taaaatattt ccattatcat aagtactgta atggataaat ccaaagatga
    35461 ttgctgacaa gaaactagcg acaggaatgc tgaacttact agaaaaaata gcgagaaaat
    35521 acactgagaa caattcttct ccaagtatca tgataggcaa aataataaat aataacgggc
    35581 tgaaagcctc atttattgga ttgcctgtta aaccccattt caaaatttgt tgcaaaaata
    35641 ccgagactgc ggcactgatt actacattga taaaaaaata tttggctata tttttgacag
    35701 gagcgacagg tttcgagaac atttttttcg tatctttttt accaaaaaca agtgtaaatg
    35761 ctataaatcc agtgatagtt aaagaaaaaa tgctaataat ggatggcgca aatagcaacc
    35821 ctaacaaacc gagtacaacg acaatagtgc ccaatttccc ttttttaagt tctatttttt
    35881 ttcctaaaat gttattcatg ataataactc ctactattca gtttttgaag atagagtcag
    35941 tatacatgaa gagttaaaat aggcaatgtt tttttatgga tatttgtatt gctaaaaatt
    36001 tatcttatat attcattttg attatactac ttttatttgt aaaaattttc tagcaaaacc
    36061 aagtgcttgc aactgattaa gcgtacaatt ttttagatgt tccgagcgta cttcaatcat
    36121 ttcaaaggag ttgctactta aatcgatatt ttttaaatca gtatcaaaaa agctagcatt
    36181 ttctaaatca ttagtagaaa acattatttt agtgagggaa cagtctacaa aatctgcgct
    36241 tgataagaca gagtgctcaa aggtactttc ttttatgttt gaaccagata aatttacata
    36301 gtccatttta caattctcga ataacgtgtt cccaatataa ctttccatca atttagtacc
    36361 tgttaattta caattgacaa atttcacgcg atgcaacatg ctttttgtca atatacagcc
    36421 tgaaaaatca cagttttcga atatacagtc ggtaatctcc attctttgaa aatcattgga
    36481 agcaaaaaat gcatacttga aaatagattt gtaaataatt ggatggcaga ttatttggtt
    36541 ttcgatgacc tctttttgtg aaaggatatt atacagttca aaatcttcgt tttcatagat
    36601 atgaaaaaag gatcctttat tcaagcttgc ttcattaact ttaggaaaaa tcatatttaa
    36661 ttacctccat tttcataaag tcatattaac aaaagctaaa ccaacttaca ttagcagaaa
    36721 atgagatagg ttttcgcctt tttcgataac gatagtgtcg ctatctcttg aaacgttctt
    36781 agaattgccc tgagagacac aaattaggcg taattctaat aaaaatctta gaataaaaat
    36841 ttttactgat ttaatttaga atgtttttaa aataaaaatc gttgccataa cagtgtattg
    36901 aaaggtttta acaatccagt aatgatttaa aaaaatctag atgtagcgta tactttgttt
    36961 atagaatgta gtgggaagaa atatattttt gggaggaaat cgtgatgtct aaaagtgaag
    37021 aaatagaaaa catggtacta aaattatatg atctcgtttt aaatccagag atcaaagaaa
    37081 aggaacgtat acttttgata gacgcaaaga caggcttaga aaaaggtcag tattatccta
    37141 aagtcataaa taatttggaa cgtagtttac gtccgttagc aatcagggga gaattgtcta
    37201 aaccagtatc accgttttat atggagatat caacaatagg aaaatttgaa aaagaattag
    37261 gtcgaggaat ggcttcggca ccgattactt ttgggcattt ataaaaacga gttattcatc
    37321 tcaatgaatt aaaaagtata gtcaatctca taatgcaggc taggttcatt tatttgaaca
    37381 gagtctgtat ttttttattc taaataaaga aacagatgtt tctttatatt gtattttatc
    37441 ctttaattaa cacaaaaaca gctagtataa actaataatg ttaattaaaa gtgtatttta
    37501 tgaaactatc gttatttatt aatgttgcat ttttgtaagt taaaaattgg aaatatagat
    37561 tgaaaaaatg aaagcaataa gtaaaataaa atgaatatat gcgaaaaaat aatttacatt
    37621 aggaaaaacc ttgtaaaaac agttttttgg catatttatt ttttataaat atttgtaaaa
    37681 taactatcaa ttttttagtt aaaagattgg aaatgagtgg gggaggaatt gaagaaagga
    37741 tttttgagag atgat
//
LOCUS       DAFBVQ010000022        36797 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.022, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000022 DAFBVQ010000000
VERSION     DAFBVQ010000022.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 36797)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 36797)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..36797
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.022"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            355..1173
                     /locus_tag="LLC22_001283"
     CDS             355..1173
                     /locus_tag="LLC22_001283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK5434569.1"
                     /translation="MDTFQGTTFTVGNFKGGVGKTKIVSMLAYDNAMIRNRKTLIIDL
                     DPQANLTQVIARTFGITDIKTTITNGVANGELASSIIKVNENLDLLACDTSFRSFSAF
                     ANKHENELDQVTVLKKLLLPIKNNYQEIFIDVPPTISEFSDNAMAASDYSIISFQTAE
                     ESLEGVNKYVNYQKFMVDRYDLDLQIIDIVPCMVEPNDDFDEEILEEAIEKYGTVVSK
                     NLIHYQKRLRRYSKIGIHLRKYKNGNFDQWDYKAHQVFINILAELDARQEFLNK"
     gene            1192..1599
                     /locus_tag="LLC22_001284"
     CDS             1192..1599
                     /locus_tag="LLC22_001284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434570.1"
                     /translation="MPKDFDIPKMMENGEFEPLLPNNKRQDVKISGEYNFSNSALSNT
                     RNITLKKRGRPVSIPDKRNKVSVPKKISPALNSKLSILQDYMTELQSEKGRISFEKIV
                     NTLADSYIQHRLGVAKEEHIREEIQEEFEKLPK"
     gene            1919..3004
                     /locus_tag="LLC22_001285"
     CDS             1919..3004
                     /locus_tag="LLC22_001285"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBK5434571.1"
                     /translation="MSTENQSQKMIIKNWGYKATNVYIEKYYKFPSFLIQNSKYSKMK
                     DSSKIAYMLFKNEFRRALHEKWIDDDGLLYLEFTQADLMDKLNCYQGKVKTILNELET
                     YNLISVVKGEFNPKTKKNEKNKYYLLQPEISADDLFIQNSFDDDLSETIDKSTSSRNA
                     EIARREETAKTLDNTGNAEIARREKTAETLDNTGNAEIAQDYYINKSLDTKRHLKDTE
                     TDQLQNQVLLDNFVEIMKEDSINTFVPEKVLSLIKTFSNTYEEAQQTVTTIHKAKHKA
                     EELEKTVVVYEELESYGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFIEK
                     AIAAKLANEQRETFNELPTVSTENWLE"
     gene            3841..4173
                     /locus_tag="LLC22_001286"
     CDS             3841..4173
                     /locus_tag="LLC22_001286"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310954.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBK5434572.1"
                     /translation="MSYTGILSLEDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIS"
     gene            4764..5093
                     /locus_tag="LLC22_001287"
     CDS             4764..5093
                     /locus_tag="LLC22_001287"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434573.1"
                     /translation="MIQKFAKMSKTAWIEKLENDLSVMRLAPKKFKREIAEKEAILSV
                     LNAVDDKCPVKISFSDIATIIEGIYYGEVDEEISSTKDLLDFLDKNKDTFIVLTDYEE
                     VTTNEKL"
     gene            5080..5421
                     /locus_tag="LLC22_001288"
     CDS             5080..5421
                     /locus_tag="LLC22_001288"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBK5434574.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLTDDNGDELSVEDTWSYLSDYIVSV
                     EIIEFVADKEE"
     gene            5535..5774
                     /locus_tag="LLC22_001289"
     CDS             5535..5774
                     /locus_tag="LLC22_001289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434575.1"
                     /translation="MARPVLEAMDMDTLTKGRYVQLLARGYSPKDVFKSLSKGTDMEK
                     ERLRKEFDYWRTHNGIKDLKPARPVIKRKKKITQD"
     gene            5841..6080
                     /locus_tag="LLC22_001290"
     CDS             5841..6080
                     /locus_tag="LLC22_001290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434576.1"
                     /translation="MNYEEIENRKKVSKEMEEKLLKMMKQKHLKRLSVMQYINDMKIT
                     GKEKACLLGSMKNFEQLRRTYVKTGSNCQLLLEVS"
     gene            6207..6896
                     /locus_tag="LLC22_001291"
     CDS             6207..6896
                     /locus_tag="LLC22_001291"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sortase"
                     /protein_id="HBK5434577.1"
                     /translation="MNKNNKTLFNPYVGVIIVFLLFSYFAYQGYQKDKIAEKVDGVTK
                     TIHIQEQAKTYQDNLTSLTDISKRQLITNQKQALEKDLKGEIAGKLVFSSTGFILPVF
                     QGANSDTLSLGVASTYYLDTEMGNGNYILAGYNVDTPSVLLSDMTDLSEGEEIDLIDA
                     HYKYQYEVSKRGKISDYSQVVQSKENNSFLSLPKAGKKPLLTLLAFQANNMKKCDVIQ
                     CELVNVEKINK"
     gene            6902..8068
                     /locus_tag="LLC22_001292"
     CDS             6902..8068
                     /locus_tag="LLC22_001292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
                     /protein_id="HBK5434578.1"
                     /translation="MSHIQELVEKLINKMSAIFLLLLVSILYLIWTVGLNPPTILFIY
                     DNAAQLVTFFVGCLFLLNLYKVKRNDLFFIAAGILFYLFFSFFRSYRGDTFYGDLIVP
                     TIIAIILIVKWTKFTVIDRSLYLVVFYVFLLVTVYRVFTEIPVPEGQSIWNPSNKLSD
                     IWINTNTIGSSLMTLALLITGFASSFGKWYMRLLSLPALILAGATIWVCQSKAALYAL
                     VIFIILEILPKKVFRNTHLSFWMYAAVSVLALPISYFAAMSDKVHLFTGREEIWRKFY
                     ETLGEKTGQIFVGMKPFFFHRGNQILGNHNTYHALVNHYGLIGFVLSIILLLSFLWLL
                     VRKRELTNGQLTFLWAFLAIMCQSFMEETLTTISWVPIVFLMLAMATHQYKTTR"
     gene            8150..8821
                     /locus_tag="LLC22_001293"
     CDS             8150..8821
                     /locus_tag="LLC22_001293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBK5434579.1"
                     /translation="MKKWLFGFLGVALIVVCSVFGYVSYQKHEGEVFKQNIEKKMPVD
                     QINAHAKSYKEDATNVNNDMSLGQMLSIQKEAIEMGVNKQVFAQIQIPALGLALPIFK
                     GANQYTLSLGAATYFYEDAEMGKGNYVLAGHNMEMPGVLFSDIQKLSLGEVMDLVSND
                     GVYRYKVTRKFIVPEYFKLIDGVPEENSFLSLPKKGEKPLLTLFTCVYTSQGKERYVV
                     QGELQ"
     gene            8874..10850
                     /locus_tag="LLC22_001294"
     CDS             8874..10850
                     /locus_tag="LLC22_001294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBK5434580.1"
                     /translation="MAINRYVKKAGMIVGMLGIIAGCFQGYRAYAEDVTQKTPPERVN
                     ITVHKLMYDQSTQLNVDIDGIKNDGYTHDQYPTGVTKYNKADYGDVEFTLGNITDQVL
                     PTEDSDLTNAKVDEIVKDVEDKGSNSEYVKNATNKITSAVDENGEITFADQPAYVNSK
                     GNVYVVYESKSAAGLVTQKAKPMVVIAPMTDNTGSGFLKDIHLYPKNIVSKLSFELTK
                     FGDDGTAQSKQTPLKGAKFELYKGEPGKGTKLGELVSDDQGKLTATDLTLGKYYFVEV
                     PSEVVVGSDQEPTADQYLLGADARNDAHNKLTFEITNDGVTSDLKASYVNYKAPVIDK
                     TVTNGTGEEHSFQIGDAVNYQGTIHIPTDIAGGTDGITVNGVKSETSPYSVFKWGDTA
                     GKGLSYVAEKADIKVTNNDGSVVLKENTDYKIENSDSGFVIDFIVNNGQVSDTVANLH
                     GQDLKMTYNMFVNDSAEIANPLTNSVDFVYNNNPFNQEEHHEKTKADVVTYGAKFLKV
                     DSGLFGTGIKATPLEGAEFAAKNAEGKYYGGLTDTDKDGVKEAVWVDDVANAAILKSD
                     KEGHFEITGLTEGDYSLEETKAPENYQKLTKEISFKVDKDSYKEENRITIKNNQKASV
                     PMTGSNGFQSYVLISCLLLGAGAISAVVYFKKKA"
     gene            10863..11615
                     /locus_tag="LLC22_001295"
     CDS             10863..11615
                     /locus_tag="LLC22_001295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5434581.1"
                     /translation="MIIRHPKKKRIMGKWIIAFWLLSAVGVLLLMPAEASVAKYQQNQ
                     QIAAIDRTGTAAETDSSLDVAKIELGDPVGILTIPSISLKLPIYDGTSDKILENGVGI
                     TEGTGDITGGNGKNPLIAGHSGLYKDNLFDDLPSVKKGEKFYIKVDGEQHAYQIDRIE
                     EVQKDELQRNFVTYLEPNPNEDRVTLMTCTPKGINTHRFLVYGKRVTFTKSELKDEEN
                     KKQKLSWKWLLGSTVFLSVMIIGSLFVYKKKK"
     gene            11631..12392
                     /locus_tag="LLC22_001296"
     CDS             11631..12392
                     /locus_tag="LLC22_001296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434582.1"
                     /translation="MRNRKWLFVCAAALFSFTAYTQLTFADRQESTDSTEQTIQTSDS
                     STIQSSDETVDSSTVDSSEEPKIAEDDQIVKQTIHVQKIISSEQLDNQGQKLEKQEGV
                     NGAKFSVYDVSDILQKMDVKDLTTDQIESQLKDRVKKLSSDQLKLISNGETKTIDQQT
                     GVFEFSVEVQANQKQAYYIVNESSPENISNSEDILLLTPVSDKNGEFLKDVWIYPKSE
                     ASQPKEEVKKIVSTGVKKNFFENCWDFVTHLFSRD"
     gene            12405..12665
                     /locus_tag="LLC22_001297"
     CDS             12405..12665
                     /locus_tag="LLC22_001297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434583.1"
                     /translation="MKLIKLLLFNFSCLTAVFLYCGLLFSKLSILPSYQLYLMRILNI
                     PAASMPLDIMEKLIRNPLFTTINLIVIVGISLVIYKKEGMKG"
     gene            12662..14752
                     /locus_tag="LLC22_001298"
     CDS             12662..14752
                     /locus_tag="LLC22_001298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBK5434584.1"
                     /translation="MNFKHSWTRRLKYVFPIMMMLGTLFGLKTANVFAEKVIVDPSNP
                     IQNVKNNFIIPKDVPNAKTNITVNGASKVYKYHVDANKGGFTDDYVGLVEGNKNIRYP
                     SFQKEYGETNLVLEGVTTNTKVNIDYGKIGTYNGKKVNIKLVLSNIHLYSDTLPWNLL
                     DNNYTKTHFRDDGYKNTNGAMSKSKKRTVLWISDNLFSGIVYHSTQMNVQLVATYEDG
                     SPVQFSGDTFISFNSLNPAGGKSTDLKGEYAHYDKMNTTDWYVRKDTVLSEFKSFYNN
                     LNVVGGHPGGSSKLTQADNDFNNLHDKLGDPKFGQGTVSFKISEANPTFVIGSSNVQT
                     WFTLSSATIFSVVPDQPEKTGVDKNGNNVNDKMLQVGDTIQYRIKQKVNRLGVDLLAV
                     YDRFELIDNLPKEVNYVDAHVESGTNKKFDVSGEVTYDKTKHQVKYAAKADTLKNRMK
                     YNGETYELVINVKVNELANQNSVAKNQGTSIINKVEKDTNIITVYFPKIPVKEVQQNG
                     KDVNGRNDGKKGTPTAPLNAGSEVQYLVTQKWHTKGVDAASDHYKQFSIQDPIEARLT
                     YKEGSAQVIDKSKGKDITSEGTLTYDSNSRTLKWEASADFLNNNLLDGREIQLIFTAK
                     TPLQSEKNIDNQAVVAVDNVSNKTNVVTIGVDPNLPQVIVPKTGSTHLVTILAVSLLL
                     LVLATFGYAVLKFN"
     gene            complement(14788..16845)
                     /locus_tag="LLC22_001299"
     CDS             complement(14788..16845)
                     /locus_tag="LLC22_001299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FIVAR domain-containing protein"
                     /protein_id="HBK5434585.1"
                     /translation="MKLLNPKTVIAIGTFAATVALAGSADAASTNVMYRLYNPNNHEH
                     FYTSSTKERDHLVKIKWGNYEGPAWEAPTSGGHLVYRLYNKGLRDHHYTASWDEVKWL
                     TKNYGWTYEGPAWRSAEKNNKPIYRLFLPGVTSGSHHYTASWKEVQWLTKDYGWKYEG
                     IGWYGADTSKPKVNKSALEALYTSVKGTKKGDYTDNTWNAFQTALNNAKKVLNDSKAT
                     QKQVDSAKNTLDSAYKGLKKKPAPTVNKTELQALYNQVKSTAKGDFTEGSWNNFQTAL
                     SNAKKVLDDSKASQTQVNNAKNSLDSAFKGLQHKPKPSEYAVTVRHMNRQTGTLLKEE
                     HVSVKAGTSYTAKARTDLTNFEAPQYQVNGNETQTQTINTNTTFTFYYDEVFLVEVKA
                     RPNKVSDTDPNIQELYNYSKSYPVVYGQSITIEAPMFTNFVLDPRESSSNTVTLNNVT
                     SNQGINFAYTHQYNVTVNHINVDTNAVLSTETQTVYEGDSFSTSWKNMTDQNYFLCRN
                     DDSSVTVDKNGQRVINNVDQNRTITFKYKNISLSDLNNYVRQKELAWLNSYRQQNGVA
                     PMQFNDIVQQAADIRAKELQVSFSHYRPGGGTFQDLLESLGCYGAKGENINSFYLYVD
                     EILSDTGAVNAMVMWKDSAAHNANLLYNNQSIVGLSHAYEVSADGSLSSDNVFISANP
                     IFK"
     gene            complement(16990..17181)
                     /locus_tag="LLC22_001300"
     CDS             complement(16990..17181)
                     /locus_tag="LLC22_001300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434586.1"
                     /translation="MYADKEKIEWLLFETGKTAYEISKHSSVAESTIADLIKKKSAIE
                     KMRFDNAAKLTKYAESISS"
     gene            17369..17824
                     /locus_tag="LLC22_001301"
     CDS             17369..17824
                     /locus_tag="LLC22_001301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300032.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434587.1"
                     /translation="MKKLIMVFTSLIAMIVILGGCGSEKNKQDSQDNGVLKPGTVWKE
                     EVGGLVHNLKIIDDTTWEYSESVWHPEQVQITVEKLKDYKGLERYKVIDSGGVDLFIG
                     KTALIVSYNKDGLETFKFIPTNEKEHRDKSEILKEYSTKSGYKLQKTSE"
     gene            17821..18063
                     /locus_tag="LLC22_001302"
     CDS             17821..18063
                     /locus_tag="LLC22_001302"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5415 family protein"
                     /protein_id="HBK5434588.1"
                     /translation="MIASLFIYPEGGIAVAKAKTPFEKAASKILERRGVSETQWKQEV
                     LEKAQFDLLRGKDKDLEGYIYQREREKLVFDEIIKH"
     gene            18081..18383
                     /locus_tag="LLC22_001303"
     CDS             18081..18383
                     /locus_tag="LLC22_001303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434589.1"
                     /translation="MFESITMNFLTQPKVVAAVDIFRALQGAATSLKNNLMIFAAVAA
                     VASIVLGGIFFFFGRRGAENGKMHVGYVLMGVGVILAAASIVVSLFGMFGQTPQGL"
     gene            18452..20506
                     /locus_tag="LLC22_001304"
     CDS             18452..20506
                     /locus_tag="LLC22_001304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434590.1"
                     /translation="MYFTISGNTKKDKELIKKATKKVGKRTAFLPKTIKYSVIETEEQ
                     LHVLGQVLEQENQSSVKLTLTLHDKEGKIEKAGTEYVFGPLDYQISEGFYPTLMDLIR
                     LDVFKETDETMSVEESYRNEKLLQVLEEELESDQRKVSQVSEVEVNDEVPWERPIFPK
                     KESKEKETVYVDEQADIPTQKSIFEEENDVMGQLEVDPFEETMEDEETAEVEVDLVEA
                     NEEPTWTEGDSQEYIEPLISEEVEKNETEIQKATVFDYILDQYPPEHEWMKEKNKLFL
                     NELYSKYQLPQTYQAFLESKEELISQGKGTLLEQLESVQSTNWHELAQEDLLATFEER
                     QQETDQEINEYATEQSSNWERTKEELNKEEQRVIEEEVQKIKERYEKKRDNAYSLCIE
                     KINNFTKTNQEALSKEKENLLKERIKERKEEFYRGLRTDKLKISKELNEQLNKLYQTT
                     TEVLMERHGQIQQELQAQIPKWKKEYEIQQQELKEQEEKQRQEEKEREQLELKKREQH
                     LAEQKVAIEKQRLEQEKEKEAAARKERQEQMDTLRQAQLNYLAQPQPVAAVQTPVNNQ
                     ANLTPSPQRSFNGWMVGCIASLSLLLGGGTVFAFNHINQSSQADSVATTASIKEEAQE
                     QARKEYEQQLEELLNRTNQSTAESSMENSKESDPSKAKEGSSDSTVHSNTSESSESNE
                     VK"
     gene            20506..23118
                     /locus_tag="LLC22_001305"
     CDS             20506..23118
                     /locus_tag="LLC22_001305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV secretory system conjugative DNA
                     transfer family protein"
                     /protein_id="HBK5434591.1"
                     /translation="MRIRETTRRKDKRFNLEKNRYLSHFYRYTPSGEELPEKHDKRIS
                     QKIFYSGLAYLPLNYVVTRIPEAFHRFEIIPGSLQGVNIFQLQEMPQLFHFDSTGFWN
                     PLTPTTSLGTRLVVSTICVVPAVLMGLKMDMWFRPLADGQKGDNRLKTLKEIQQIYPQ
                     IPESKGSFPGYGGIPITHYKKYWYIQTDTVNTCIVGTSRSGKGQIEVLATIDNLSRAE
                     RQSSMVVNDPKTELYVASKDELEARGYDVYAFNITDPLQSMSDNPLALIVKYWKRGDI
                     DTATQLTNTFTNTIYYDANASDNKYFNENAQKAVNALIFALLEQADQTGDYSKLTPNN
                     LVELLSEIGGFNYYPDPENEFKQLNALDEFMNQLPPGNIAKKQYGATKIGSDKAKGNI
                     LSTAITGLNPFTLTKIAKMTSQSTIDYKSIGFPKYLDLKLHESLLNQRIVVEFYHKGK
                     KFHEERVKVGYRGFCEINFDCHLEQGDHVCLKYNHQGKQYVAWYEFSQKVLKDEEGKI
                     VYRKKRGETHLPELEKEAVLTLDEKKSNLLVESIRMHYTDKPMAIFMLTPDYDPSNHI
                     IVSIFLSQLYKELSTQCVKTKGDKCHRRIHFILDEFGNMPPMDNMEGIMTVTAGRNML
                     WDLFIQSYQQLYAKYGEQNAAIIKENCQTHIYIMSTDDNTIEEFSKKVGNKTVEQENS
                     TINSLGMNTHINRNVDSDRILTPERISTFLEGETIVLAPLKRQDLKGHKIRPYPIFNH
                     GETNLPYAYQYIEDFNPSWDINDIDIHCTHADLDLKALQIDYDYFLPDEYARNLYHGL
                     HDQLEEKNEENMFYKIVQSFENETAKKLLIQFYEEQATDRLQEYVEKLIKNEEISEMI
                     RKRLLLEAEKAVKE"
     gene            23115..25493
                     /locus_tag="LLC22_001306"
     CDS             23115..25493
                     /locus_tag="LLC22_001306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434592.1"
                     /translation="MIIGGIFSGIADWWSGLFGEGDADPKTVTKVLQDYGNYLQYQDV
                     FSWICNTFLWGLIKGLYNLNTLLEKTIYQSFDLKDLLNAAGVNELFQSLISKVLALFC
                     VVTLIYLGLKFFMSKHPPKVKNILVNLFMAMILIFGGSSLIDEGLNISKNFYGDVTAA
                     NKADKTGSPAFQIIQNNVIDVSTLLATDPNKVESLPTDKRNALTAKNFKTANINGIIT
                     PDQAKKMSESSDISTVQKDRLKALQYRLELDDNGKEIPVQISDEGLAKYVYTSGYRRY
                     ISSPGIILAGESSLSVAYLFILFTIVTCIIELVFKKFYLVIAASTDFETGQRMKSAIE
                     DISQSFLLLAFTILELRIYTLMLSGIGDLHAVGKINGFLYVVALIVLTIALFKGSQSV
                     TKIFGVDTSLKNGSNSLLSMFALGNIAKNVGSGAKNLASAGKSGLSHLNDIRKNGFGH
                     RKDITHDNGEEQSDDKATTVPNSKKTVSEMFGKAKNGVSKAAEGLGYVNERGLKGTVE
                     DLTEKAKDTLEEKLDGTRAKEFAEAVKNPSEALEKQKEKASAVKEGLKDAYGEGQVNA
                     AVKANTTSEKENQEGAAIPSAKDHQDELHSNENSIGEKDSEEGQHGQLPKTDPEQYRY
                     KSNINSENEKRISDLPKRNQEVQTDEDSIDLPNDNGIEVGTEKSTKIGLPKTQNLPMK
                     DSRLNQFKENDQSFVHQSPAGTVQMKSSRLPENGNLTTVSYNLAESGETENASVQNIV
                     TKEAAPKPINKVHNGYRPANVAFTAPTKINVTRETKNRNNELKEQLLKDIKP"
     gene            25554..26096
                     /locus_tag="LLC22_001307"
     CDS             25554..26096
                     /locus_tag="LLC22_001307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401498.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434593.1"
                     /translation="MEDILIATFITALGAFLTIFVVTIKGFKDTDSLQKDHQSILDGQ
                     KTHTESIIVHLSEGFTYLKDAMPTFTVKLTEIFHSVEQISSELKEQRQQKDRQLGSLN
                     FRQETIQESLENVNRLNDEMQRVHLENEELRAQNYDLIQKKRNLEQKIVELKEENRQL
                     NYQLRRGKNRSRDLGNELEL"
     gene            26174..26506
                     /locus_tag="LLC22_001308"
     CDS             26174..26506
                     /locus_tag="LLC22_001308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434594.1"
                     /translation="MDKYIHMKNPPRFSGEWKFFAFFFLDLLTLGGCFFWAKIVNNLV
                     HLPLFFALLNYGLWLAIALVIVWRPYNNPGQRQIFAIIESIFFTDKNHYHALDPNRNY
                     HGTYKEDE"
     gene            26507..27100
                     /locus_tag="LLC22_001309"
     CDS             26507..27100
                     /locus_tag="LLC22_001309"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302855.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434595.1"
                     /translation="MRVKGQNSVDKKSILQFGKPEERSILDLFPYKSCTEEGVLITRE
                     DHFQRYYRVVSTDVEGLNEQEKLERMNQLTTVMRTYVPTIKLVSLTTETDLTEQIVQK
                     RQLLDKNRMEQSLGRNLQRLRKYEKKLVEEIQELKRAEQERPDLSFFFVIEGKTIKDL
                     QTRNRQLMRSSGILGLKPLYKKELIKILYRMNNMNDE"
     gene            27122..29146
                     /locus_tag="LLC22_001310"
     CDS             27122..29146
                     /locus_tag="LLC22_001310"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATPase"
                     /protein_id="HBK5434596.1"
                     /translation="MLDVIKTAFSTQSNQKVIDPLKQLGNREIEILKSKGYDLDFLKQ
                     VMPQGGLNFDEEYVTYGNGYSRCVTVYHYTKNPTLFWLANLMNNPHTVATLDVSTDEK
                     QKVIDQINRALDELNDRSDNERKATDRNKSAEEYLELAEYARKLTSNGEISKQVKVRV
                     HVYGNTIQEVDERAQELIENLKGMDYRAVTYLHKTKRDWQSMFTMFDEQAEWFGNIKG
                     QSLPSLNIGGGFPFHHQTLKDPGGTQYGETMTGGPFVWNATYKNSVRLSTNTLLLGMM
                     GAGKSTVLKMIAEAHLAAGDFIWGFEKGKDFIPFLKEYNGIMVRLDGSDGMINPLEIF
                     ATRTYDEASSLYDDGSVKDLKINEAASYQTHLDKVVYQVQLVSPQLKGTMKAEFKTYL
                     NRFYEEYGTVPRGFTSSNSRSNTDTQVTGKDPEAYPTFKEFLAFLGQLELPGASQEKK
                     NRKEEMESIVESLCETYGMIFDGHSTIRHLDQQQLVFFDIDSITGLDRGVQQCQMYMA
                     MTLIWNQALIQGRRQRRLIKEKQMEEQDFKRFLAMIDECHNAINPDFIETVNYVTNFQ
                     REMRKVEAMTVLATQSPQEMVPENMSSDNFSKLKKVFEFSSTKIFMRMDESILRHIEG
                     LVGKSMTNSELESIPQQNQGDAVINFGSKETIRVHFSPNKRQLKLFDGGK"
     gene            29146..30345
                     /locus_tag="LLC22_001311"
     CDS             29146..30345
                     /locus_tag="LLC22_001311"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosaminidase domain-containing protein"
                     /protein_id="HBK5434597.1"
                     /translation="MENQNESLIKQYVKRRAKRRLFLWVFGTSAGLITILITVFVTLF
                     LILAAGSIDNSDSSSGGEAFTGEYSEGLPIYKEIKGRGPFSDEIAQYAVGAAVKYKLL
                     PSVILSQYGYESAFGTSASARNDLNYFGITWFDGCLFPKGTARGIGGIEGGWYMKFPN
                     SKAAFSYYGFMVATQSNFNACVGNKSPGASLLILGRGGYAAAGITEDSAYYKNCMSII
                     NTNKLMEYDEFAIKHWREGGGTGGTITGSWGNPFPGSSLDKNSFSGGQLFGKNPGGEF
                     RPNGFHDGLDFGSVDHPGSEIHAVHGGKVVYVGNPGISGLGACVIVINYDGLNMVYQE
                     FANSTGNSRVKVGDQVKVGQVIGIRDTAHLHLGFTRMDWRQAQGHAFIDDGTWIDPLP
                     FLNSSKK"
     gene            30361..31005
                     /locus_tag="LLC22_001312"
     CDS             30361..31005
                     /locus_tag="LLC22_001312"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434598.1"
                     /translation="MENKTLKIVLTAAISVSLIGNIALFWQLKEEQETNTYKIEEVAK
                     NASDKLKKNSSEAQAKIDKLNQTINEKNQEIDQLKQQDGTKAKEEVTEAQRKTAEEFG
                     QLAIDKSLSRNELTEKLKDVATQEVIDKLSPVDDDHQHDDYGSYSFTLGDVQTYAQTS
                     SVKEEQNFVVFVDYTIGNPQFKDVKPQKIKGGLTVTEKQVDGQWKVTDFSYFTR"
     gene            31016..31822
                     /locus_tag="LLC22_001313"
     CDS             31016..31822
                     /locus_tag="LLC22_001313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434599.1"
                     /translation="MSKKKGARQRFKKRKSYLRWLGIFMILGFLILASPIYTHKKVDI
                     PDEVSTNAFLNTKELTMVSKEKGANQQLVFEFAIDDEDQSLLKELANLNYRVEVKTAK
                     GDYQAIKAKVIKVSDDYFVVKLAHVPEEYIAMRLTIIPEKIDPKVDMQEPQDLIFYIH
                     EDKVKDHVKDEDYEQHAINYKVKGYKKEQKAAQKQIESFQATIDLNEELVKKLKDQLP
                     YQVAEDQENTENKINSYQQEIETSKTQMKDQEESIQKLQEKIDRMTKENI"
     gene            31845..32074
                     /locus_tag="LLC22_001314"
                     /pseudo
     CDS             31845..32074
                     /locus_tag="LLC22_001314"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731508.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            32095..33168
                     /locus_tag="LLC22_001315"
     CDS             32095..33168
                     /locus_tag="LLC22_001315"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4199 domain-containing protein"
                     /protein_id="HBK5434600.1"
                     /translation="MKKTYQKFLWISYIVLFIVGFLVSVSVIVGTLFLLFSDEDLVLK
                     GLMSTLSCVMLLYLCIQINEIMPPHWQEKKKEFKEEIEIKSNDWIEYTWLPLKRNSKR
                     KEFWALQLWPIGKLFIYMASLMVTLIGYLVVVYGVAYYLLSEPKQIAASNIFTAVMTL
                     MCVMCFSIFSYLLVQFIRQNLTMSKLFKSLLDLLILGSMLTTLTDRFEQSEKTVEGIK
                     NFLTTIDQFINGYMYLFEVGFILTLFGCVFIKLIKRSIEKEMVIDLIPTLSGYEYYVD
                     FGKYEELIHTDIVHTSIHEVTVKGIRSTLKDGQETKTIDRRKEVYNFYKVEASLRYGI
                     GKLRLDGSNIQQNKPYVLGKVVI"
     gene            33212..33481
                     /locus_tag="LLC22_001316"
     CDS             33212..33481
                     /locus_tag="LLC22_001316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434601.1"
                     /translation="MILLYRIVLIVGTELKILKKEQLFKVKEHHNQLLCIKTGTMNIQ
                     YRTEYLELTNQTDFLSIREQHKQEKLMATYSQLIDEWEQFKESKT"
     gene            33757..34032
                     /locus_tag="LLC22_001317"
     CDS             33757..34032
                     /locus_tag="LLC22_001317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434602.1"
                     /translation="MEVKIRDIDEKTIQRIDRRCIELSERTGTKWSRNRYLKVLIEND
                     FDHELMDHRKDQFDRLLEKFVDIQTYNTKILEEYIATNNQLIALLIE"
     gene            34074..34496
                     /locus_tag="LLC22_001318"
     CDS             34074..34496
                     /locus_tag="LLC22_001318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434603.1"
                     /translation="MAKATRKHVYLYDMHIEVLDEIISTHEDISNYSEAVRHLCMMYD
                     PKIEEKINPIQIKLNAMGKEISILTEMVSEFADLHLKDTGILIGTNSTVYQEAKERVE
                     GKIKANQTKKYSPKIKKPINESVHARVDPFDPTKFLKR"
     gene            34516..36108
                     /locus_tag="LLC22_001319"
     CDS             34516..36108
                     /locus_tag="LLC22_001319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434604.1"
                     /translation="MNKSPAVILTCQFTLPNKKSFSTYIDYMTREKALEEKERRTPDE
                     EQELQRIKNALEDFYIPEGETFSESKTDKEFSETSNEAQSLMEHGINFDKLEEQDFTK
                     YLSYMTRHYALEQKKELTQREQKEYQRLNQAMKKYQTEPHKKASGNLPGVFSMASDEV
                     KGSDLKEIKQIFQRGQQKGSIIYQDVVSHDNSYLEKMGLYDPKTDTLDEEGLKAAGRK
                     MMETLFEKEQLNETGYWMATIHRNTKHIHIHFAVVEKENTRKPYTEVENGVSYIVPKG
                     KRRQATLDAMKTNYVHELERFSYEKDRMIGMEKRNLLTRKSDLRNTLTKVVKEPARYD
                     RHAMNLLNEVYKTLPDKRSEWHYGDEKRTKLSPYTREKLDELTKYVLTKEPEYQEYIQ
                     ISKSLKEEAKSLYGESKRESKDAEKNALFDLKKRTGNAILTELKKQDSQIKPLIESMD
                     QMQSIYNERSFRTLKQLPTNEYKYSYEEFMKRRKQFQQRVVTQRSLRQLNRTINAHEE
                     KYHASKAYEEQQRRIQMEQERQ"
     gene            36129..36464
                     /locus_tag="LLC22_001320"
     CDS             36129..36464
                     /locus_tag="LLC22_001320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434605.1"
                     /translation="MKQYLDQWKVIEGSLREERIEQLPDCLEKEHLFQIREMLRNEQF
                     DPNQFLVVEYSATGVYCCNHVKGEKYFIIQEYEGKLAPYYTTWEMNEEGINNFPCKSI
                     EESISLTEC"
     gene            36610..>36797
                     /locus_tag="LLC22_001321"
     CDS             36610..>36797
                     /locus_tag="LLC22_001321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434606.1"
                     /translation="MAYSTIGVVVEKSRDNLVFVTEIQTGRAFVVTDKAAKAYQSGDI
                     LTLNLTTKTFVDAAEDYP"
BASE COUNT        13369 a         5606 c         7350 g        10472 t
ORIGIN      
        1 gtatatgatc taagtcttgc ttctagtatg aatatgaccg atgtatacga aaagttatta
       61 atactagaaa atgaatatga tcaattcaat tcaaatcagc agcgaaaagt aaagaaacag
      121 atagactaga atagctattt tcgaaaagca atatttaagg tataagttat acctttaata
      181 ataaaagtat aagttatacc ataaatatat atggtataac ttatactttt attattaaaa
      241 accgctatat ccaaacgttt ttagatatta ttatttaagt tatactttta atgttgacca
      301 tttccgatat ataagttata ctttaattat caattaaaga ttgggaggat ttacatggat
      361 acttttcaag ggactacatt tacagttggc aattttaaag gaggagtagg taaaactaag
      421 atagtcagca tgcttgctta tgacaatgca atgataagaa atagaaaaac gcttattatt
      481 gatttagacc ctcaagcgaa cttaacacaa gtcatagcaa gaactttcgg tataaccgat
      541 atcaaaacca ctataacaaa tggtgtcgca aatggagaat tagcaagtag tattattaag
      601 gtaaatgaaa atcttgacct tctggcatgt gacactagtt ttcgatcatt ctccgctttt
      661 gctaataaac atgaaaatga attagaccaa gttactgtct tgaaaaaatt acttcttcca
      721 ataaagaaca attatcaaga aatatttatt gatgtaccac caaccattag cgaattttcc
      781 gataatgcta tggcagcttc agactattcg ataatttcat ttcaaacagc tgaagaatcc
      841 ttagagggag tcaacaaata tgtaaattat caaaaattca tggtcgatag atacgatctt
      901 gatttgcaaa ttatagatat tgtaccttgt atggtagaac caaatgatga ttttgatgaa
      961 gaaatcctag aagaagcaat tgaaaaatac ggaaccgtgg tatccaaaaa tctcattcat
     1021 tatcaaaaaa gattgagaag gtattctaaa attggtatac atttaagaaa atacaaaaat
     1081 ggaaattttg atcaatggga ttataaagca caccaagtat ttataaatat tttggcagaa
     1141 ctagatgcta gacaagagtt tttaaataaa taataaggag ttgcataagt aatgcctaaa
     1201 gattttgata ttcctaaaat gatggagaat ggtgaatttg agccattatt acccaataac
     1261 aaacgccaag atgtgaaaat aagcggtgaa tataacttta gcaatagtgc attgagtaac
     1321 acaagaaata ttacattgaa aaaaagaggc cgaccagttt caattcctga taaaagaaac
     1381 aaggtatcag ttcctaaaaa gatctctccg gcattaaata gcaaactctc aattttacaa
     1441 gactatatga cggagttaca aagtgaaaaa gggagaattt ctttcgaaaa aattgttaat
     1501 acattagcag actcatatat ccagcataga ctaggagtag caaaagaaga acacataaga
     1561 gaagaaatac aagaagagtt tgaaaaatta ccaaaataat tttttttcat gcggtattca
     1621 attaaagtat aagttatact agataaatga atattaaagt ataagttata cattaaatat
     1681 ttaaggtata acttaataaa caacgtgtaa atttgcgatt aaatcaacat tataaaatta
     1741 ttatttaaag tataagttat acattatttg tatttaaagt ataacttata cttatttttt
     1801 taatatataa cttatacctt aaatactgaa agtgttttat tcacccttaa tacatggtat
     1861 agttcacttg ttgaaaatcc tgaatatata caagtttcta agaagaagga gaaatttaat
     1921 gtctacagaa aatcaatctc aaaaaatgat aattaaaaat tggggatata aagcaacgaa
     1981 tgtttatatt gaaaaatatt ataaatttcc tagtttttta attcagaatt ctaaatactc
     2041 taaaatgaaa gacagctcaa aaatagccta tatgcttttt aaaaatgaat ttcgtagagc
     2101 cttacatgaa aaatggatcg acgatgatgg tctattatat ttggaattta cacaagcaga
     2161 cctaatggac aaattaaatt gctaccaagg caaagtaaaa accattttaa acgagttaga
     2221 aacatataat ttgatttcag tcgtaaaagg agaatttaac ccaaaaacga aaaaaaatga
     2281 aaaaaataaa tactatttac ttcaacctga aataagtgcc gatgatcttt ttattcaaaa
     2341 ttctttcgat gacgatttaa gcgaaactat tgataaatca acctcttctc ggaatgcgga
     2401 aatcgcacgt cgagaggaaa ctgctaaaac ccttgataac actggaaatg cggaaatcgc
     2461 acgtcgagaa aaaacagctg aaacccttga taacactgga aatgcggaaa tcgcacaaga
     2521 ttattatatt aataaatctt tagacactaa aagacactta aaagacactg aaacagacca
     2581 attacaaaat caagttttgc tagataactt cgttgaaatc atgaaagaag acagcataaa
     2641 cacatttgta ccagaaaagg tattaagctt gataaaaaca ttttctaaca cttacgaaga
     2701 agcccaacaa accgtcacca caatacacaa agcaaaacat aaagccgagg aacttgagaa
     2761 gacggtagtt gtgtatgaag aacttgaatc ttacggaatt gatgcggata aaggattata
     2821 tatgacgttg ctgaaagctt atcaaaaaca aaagactgag aaagtaaata atttgcagaa
     2881 tttgattttt gtgtatgtaa aaaactggtt tattgaaaaa gctattgcgg caaagcttgc
     2941 aaacgaacaa agagaaacat ttaacgaatt accaacagtt agtacggaaa attggctaga
     3001 gtagttgata aaaagcgaac actataaaaa tgatcaattt taaattagaa cttttttaca
     3061 attttaattt tattacaaat gttacaaata aatagttatt attccggagt ttttagatta
     3121 aaagtttatg aaaacaatca caaacgtagg ttttaatgtc ataatcgtta gatattttag
     3181 ttatttttca ttcaaaaaaa cagggaacta gtgtttgcat atgtattttt ttgagttata
     3241 ataattcatg aagagaggta attcacttat ttacccaagc tgaaaagcct gatattactt
     3301 cttttcaggc agtgctgcta atattcaatt acactttttt gtataaattt agttgtttta
     3361 aatttaattg tctgctatgc ttgtgatgaa ttgattttcg ttctgcactt ttggacgata
     3421 aatttggaca attgaaaata caaaaaaaag aaaggccctg tgagactcgg aaggctacca
     3481 accttcgtcg acgtccacag gtggcattaa gtctataccc cttaatgcgt ttacctttca
     3541 gtgttacggt attacccgta acggatttag tataacagat attcaaaagt gataccactt
     3601 tttttggctg tgttaaggtt aaaaatacgt gatattacga tgaatctatg cctaagcata
     3661 atgttataaa aatgtccgtg gggctctttg ccgtatgacg aacgctgaaa ttagagggaa
     3721 cgcatgtttg aatgcgttcc ctcttttttg tttgtcatga acgaaaatca attctctatt
     3781 tttgaaaaat aacaagaaaa acttgttaaa aatatttaaa gtaagtgggt ggattatttt
     3841 atgtcatata caggaatttt gagtctcgaa gatatttgtc actacggtaa acggtgtacc
     3901 gctacagaaa agatcacgaa gaaactatca actggtcaaa gtaaaaccgt tgtgcagtgt
     3961 aagaaatata taatccagaa agacaaagtc tcagaagaaa tgatttatta cattgggaaa
     4021 caaaaacaaa taattttaaa agatcctatc cctttaaaag agctatatcc aacaatcaaa
     4081 catgtttatg accaaaacgg tgtactgatt ggtcgaagaa aaaatggagt cttgcgttgt
     4141 accgcaaaag ggatggggcg tttaatcagc tgaattgatc attctcataa cttgtatttt
     4201 atcgtttttc gcttgcttga aaatattgtc gagacttcta aaggaactta gaatcactag
     4261 aaaaataagg agtagacttg atctatcaac aattcccttc ggggagtgac ggggtaggtt
     4321 tttacgattg gtaacgtaaa aaattggtca atcgagtaaa tgcccttgtt tggatagtgg
     4381 tgaaatgaat ttgtgtaaat aatatgcaca gagtaaacaa gagggaattt agaagttaga
     4441 caagttagaa tagcgcctag attaatcatg agcagctact aagggatcta ggctttgacg
     4501 caaactcatg gaataaggag taggtcttct cgtaatgggg aggacgcaca agaaattgtg
     4561 tcgtgtgctg cagtacatgt agatacttgc gaggacgttg atcattggat caatcgagca
     4621 tttaccgctg tctactaggg tttctcgttt cggacgccat aaacgagtcg atttatttta
     4681 tatatttttg agtgaacgaa aaacgataaa gatattcgtt atgaagtaaa actaatttag
     4741 tagatagcaa aggtggtaga ggaatgattc aaaaatttgc gaaaatgagt aaaactgcat
     4801 ggattgaaaa gcttgaaaat gacttgagtg tcatgcgatt agctccaaag aaattcaaac
     4861 gagagattgc agaaaaagaa gcaattttgt cggtattgaa tgcggtagac gataaatgtc
     4921 cagtaaaaat tagtttttca gatatagcaa caattatcga aggtatttat tatggtgaag
     4981 ttgatgaaga gatatcttct acaaaagatt tattagattt tttggataaa aacaaagata
     5041 cctttatagt actaactgat tatgaggagg ttacaacaaa tgaaaaatta tgatccgaat
     5101 atacgattgg gcacacatac gattaaggtt tctttccaac gttgggatta caaaggattt
     5161 gtgacgttta gaagaggcgg aaattgtaaa ggattagatg ttttagcatt agacgaggat
     5221 gatttatacg atcaaacatt gactgataat ccaattggat tcggcttgct acctgaagat
     5281 gatgaaggta atgaatggtt taaaatgacg cttacggatg ataatggaga cgaattatct
     5341 gttgaagata cttggtcata tttgagtgat tatattgtca gcgttgaaat cattgaattt
     5401 gtagcggata aagaagaata aaaactggag gaataaattt tacagataaa ggcttagaag
     5461 gagtcacgac gaataataaa aaggtagtat taccttaggc attgagtaag gaatttattt
     5521 aggaggaaaa ttagatggcg cgaccagttt tagaggcgat ggatatggat actttgacaa
     5581 aaggaaggta tgtacagctg ttagctcgtg gttattcacc taaagatgta ttcaaatccc
     5641 tgtctaaagg aacagatatg gaaaaagaaa gattacgaaa agaattcgat tattggagaa
     5701 cccataatgg aatcaaggat ttgaaaccag cacggccagt aattaaacga aagaaaaaga
     5761 taacccaaga ctgaagtgta gagcgtatgt gatcataggc ttttttattt ttgcaaaaaa
     5821 caagaaaggt aggaaaactc atgaattatg aagaaatcga aaacagaaaa aaagtgtcga
     5881 aagaaatgga agaaaagttg ctaaaaatga tgaaacaaaa acaccttaaa agattatctg
     5941 tcatgcaata tatcaatgat atgaagataa caggaaaaga gaaagcttgt ttgttaggtt
     6001 caatgaaaaa ctttgaacag ttgaggcgaa cttatgtaaa aacaggttcc aattgccaac
     6061 tattattaga agtttcttga cgattatgat atgaaaatga tcaattatga tgtggcattg
     6121 ttattgaata aaaagaatag taaaatttaa catggtttat cttggttaga tgtaggtaaa
     6181 ttaattcata tatagaaggt agatagatga ataaaaacaa taaaacttta tttaatcctt
     6241 acgtgggcgt aatcattgtt tttcttcttt ttagttattt tgcttatcaa ggttatcaaa
     6301 aggacaaaat cgctgaaaaa gtagatggtg taacaaaaac aatccatatt caggaacagg
     6361 ctaaaaccta tcaagataat ttaaccagtt taacggatat ttctaagaga caactgatta
     6421 ctaatcaaaa acaggcatta gaaaaggatc tcaaaggtga aattgctgga aaacttgttt
     6481 tttcttctac aggatttatt ctccctgttt ttcaaggagc gaatagcgac acgcttagtt
     6541 taggagtagc ttctacttat tatctagata ctgaaatggg aaatggaaat tatattcttg
     6601 ctggttataa cgtagataca ccaagcgttt tattatccga tatgactgat ttatctgaag
     6661 gagaagaaat tgatctaatc gatgctcatt acaagtatca gtatgaagtc tccaaaagag
     6721 gaaaaatttc tgattacagc caggtagttc aatctaagga aaacaattcc tttttatcct
     6781 tgccaaaagc aggtaaaaaa ccactactca cactgttagc ctttcaagca aataatatga
     6841 aaaagtgcga tgtgatccag tgtgaattag tcaatgtaga aaaaatcaat aaataaggga
     6901 agtgagtcac attcaagaac ttgtagaaaa attgatcaat aaaatgagtg ccatttttct
     6961 gttactgttg gtatccattc tatatttaat atggacggtg gggttaaatc ctcctacgat
     7021 attatttatt tatgataatg ctgcacagtt agtgacgttt ttcgtaggct gtttgtttct
     7081 tttgaatctg tacaaggtaa agagaaacga tctattcttc attgcagcag gcattctttt
     7141 ttaccttttc ttttcttttt ttagaagcta ccgaggagat actttctatg gtgatctgat
     7201 cgttccgaca attattgcta ttattttgat tgtaaaatgg acgaaattta ctgtaattga
     7261 tcgtagcttg tatcttgtag tattctatgt ctttttactc gtaacggttt atcgagtatt
     7321 tactgagata ccagtaccag aaggacaaag tatttggaat ccatcgaaca aattatcaga
     7381 tatttggatc aatacaaata cgataggtag ttctttaatg acattagccc ttcttatcac
     7441 aggatttgct agttcatttg gaaaatggta catgcgattg ctatcattac cagcgttgat
     7501 tcttgctggg gcaacgattt gggtttgcca atcgaaagca gcattatatg cgcttgttat
     7561 cttcattatc ttagaaattt tacctaagaa ggtttttcga aatacacact tgtccttttg
     7621 gatgtatgca gcagtttcgg ttctagcttt accgatttct tattttgctg caatgtcaga
     7681 caaagttcac ttatttacag gacgagaaga aatttggcgc aaattctatg aaacattagg
     7741 cgaaaaaaca ggacaaatat ttgtagggat gaaacctttc tttttccata gaggaaatca
     7801 gattctaggt aatcataata cgtatcacgc actcgtcaat cactatggat tgattggttt
     7861 tgttctatcg attattcttt tgcttagttt cttatggttg ctcgtaagaa aacgtgagct
     7921 gacaaatgga caactaacat tcttgtgggc ttttttagcg atcatgtgtc aatcgttcat
     7981 ggaagaaaca ttaacgacaa tcagttgggt gccaattgta ttcttaatgt tagcaatggc
     8041 tacacaccaa tataaaacca ccagataaat gaaatagaat agtaataaga gaaaacactt
     8101 tttcgttgtg aaaaagtgtt ttttgttttg tctgaaagga ggcagatgga tgaaaaaatg
     8161 gttatttggt tttttaggag tcgctttaat cgtcgtttgc agtgtgtttg gctatgttag
     8221 ctaccaaaaa catgaaggag aggtgtttaa gcaaaatata gaaaaaaaga tgcccgtaga
     8281 tcaaatcaat gcacacgcaa agagttataa ggaggatgca acgaacgtca ataatgatat
     8341 gtctttgggg caaatgttgt ccatacaaaa agaagcaatc gaaatgggcg tcaataaaca
     8401 agtatttgca caaattcaga ttcctgcact tggtttagca ttgccaattt ttaaaggggc
     8461 aaatcaatac actttgagtc ttggagcggc tacttatttt tatgaagatg ccgaaatggg
     8521 taaaggaaac tatgtcctag caggtcataa catggaaatg ccaggtgttt tattttctga
     8581 tattcaaaag ttgtcattag gggaggtgat ggacttagtt agtaacgatg gcgtctatcg
     8641 ttacaaggta acgcgtaaat ttatcgtacc tgagtacttt aaattaatcg atggcgttcc
     8701 tgaagagaac tctttcttgt ctttaccaaa gaaaggagag aaacccttat taacgttgtt
     8761 tacttgtgtt tatacgtcac aaggaaaaga aagatacgtg gtacagggag agctacaata
     8821 acaagaattt aatcaacgcg agtcgttgaa atatgaaatg aggagagtaa aaaatggcaa
     8881 taaatcggta tgtaaaaaaa gctggaatga ttgttggaat gttaggaatc attgcaggct
     8941 gctttcaggg gtatcgagct tatgcagaag atgtcacgca aaaaacgcca ccagaaaggg
     9001 tcaatatcac ggttcataaa ttaatgtacg atcaaagtac gcaattgaac gttgatattg
     9061 acggaatcaa aaatgatggt tatacgcacg atcaatatcc tacaggtgta acgaaataca
     9121 acaaggcaga ttatggtgat gttgagttta cgttaggaaa tattacggat caagtattac
     9181 cgactgaaga ttctgatcta accaacgcga aagtggacga aatcgttaaa gatgtagaag
     9241 acaagggatc taacagtgag tacgttaaga atgcaaccaa taaaattact tcagctgtag
     9301 atgaaaatgg tgagatcact tttgctgatc aaccagccta tgtcaattcc aaagggaatg
     9361 tatatgtggt ttatgaaagt aaatccgctg ctggattagt cacacaaaaa gcaaaaccaa
     9421 tggttgtgat tgcgccaatg acagacaaca caggatcagg atttttaaaa gatattcatt
     9481 tgtatccaaa gaacattgtt tctaagttga gttttgaatt aacgaaattt ggtgacgatg
     9541 gcacagctca aagcaaacaa acacctttaa aaggggcaaa atttgagtta tacaagggcg
     9601 aacctggaaa aggaacaaaa ttaggagagc ttgtatcgga tgatcaagga aagctgactg
     9661 caactgattt gacgttagga aaatactact ttgtggaagt tccttcagaa gttgtagttg
     9721 gatcagatca agaaccaaca gcagaccaat atttgttagg cgcagacgct cgcaacgatg
     9781 cgcacaataa gttaaccttt gaaattacga atgacggcgt gacaagtgat ttaaaagctt
     9841 cctacgtgaa ctataaagca ccagtgatcg ataaaacagt gacaaatgga acaggagaag
     9901 aacattcttt ccaaattggt gacgcagtga attatcaagg tacaattcat atccctacag
     9961 atatcgcagg tggaacagat gggattacag taaatggtgt aaaaagtgaa acttctcctt
    10021 acagtgtatt taaatggggc gacacagcag gtaaaggact ttcttatgtt gctgaaaaag
    10081 cagatattaa agtaacaaat aatgatggtt cagtcgtatt aaaagaaaat actgactata
    10141 aaatcgaaaa ttctgatagt ggttttgtga tcgattttat cgtaaataat ggacaagtaa
    10201 gtgatacagt tgcgaattta catggtcaag atctaaaaat gacttataac atgtttgtga
    10261 atgatagtgc tgaaatcgca aatccattaa caaatagcgt ggatttcgtt tataacaata
    10321 atccatttaa tcaggaagaa caccacgaaa aaacgaaagc tgacgttgtg acttatggcg
    10381 caaaattctt aaaagtcgat agcggcctat ttggaacagg tatcaaagca acaccgcttg
    10441 aaggcgcaga atttgcagct aagaatgcag aaggtaagta ctacggtgga cttactgata
    10501 cagataaaga tggtgtcaaa gaagcagttt gggtagacga tgtagcaaat gcagcaatcc
    10561 taaaatcaga taaagagggt cattttgaaa tcactggttt aactgaagga gattactcac
    10621 tggaagaaac aaaagctcct gaaaactatc aaaaattaac aaaagagatc tctttcaaag
    10681 tagacaaaga ttcatacaaa gaagaaaacc gaatcacgat caaaaataat caaaaagctt
    10741 ccgtaccaat gactggtagc aacggtttcc aatcttacgt attgatctct tgcttgttgc
    10801 ttggggcagg cgcaatttct gcagttgttt actttaagaa gaaagcctag aaggatcagc
    10861 taatgattat cagacaccct aagaaaaagc gaatcatggg taaatggatc attgctttct
    10921 ggttactttc agctgttggt gtcttacttt tgatgcctgc tgaagcgagc gtggcgaaat
    10981 accaacaaaa tcagcagatt gccgcaatcg atcgaacagg aacggcagca gaaacggatt
    11041 cttctttgga tgttgctaag attgagttag gcgatcctgt tggtattctt acaattccaa
    11101 gtatttcttt aaaactacca atttatgacg gaacttccga caaaatttta gagaatggtg
    11161 tagggattac ggaaggaact ggcgatatta caggaggaaa cggtaaaaat cctttaatcg
    11221 cagggcacag tggactttat aaagataatc ttttcgatga tttgccttca gttaaaaagg
    11281 gagaaaagtt ttatatcaaa gttgatggtg agcagcacgc ttatcaaatc gatcggattg
    11341 aggaagtgca aaaagacgaa ctacaaagaa actttgtcac ttacttagaa ccaaatccca
    11401 atgaagatcg agtaacgcta atgacatgta cgcctaaggg gatcaacaca caccgtttcc
    11461 tagtgtatgg gaagcgagta acctttacaa aatcagaatt aaaagatgaa gaaaataaga
    11521 aacaaaaatt atcttggaaa tggcttttag gaagtactgt ttttctttca gtcatgatca
    11581 ttggttcgct atttgtttat aaaaagaaaa aataaaggag ggtaaccaac atgagaaata
    11641 gaaaatggct atttgtttgt gcagccgctc ttttttcttt cactgcctac acacagttga
    11701 cgtttgcaga cagacaagaa agcacggata gcacagaaca aacaatccaa acgtcagata
    11761 gcagcacgat tcaaagcagc gatgaaaccg tcgattcgtc aacagttgat tcttcagaag
    11821 aacctaaaat tgctgaagac gatcaaatag tcaaacagac cattcacgtt caaaaaatta
    11881 tttcttccga acaattagac aaccaggggc aaaagcttga aaaacaagaa ggagtaaatg
    11941 gcgcgaagtt ttctgtttat gatgtatcgg acattttaca aaagatggat gttaaggatc
    12001 tcactactga ccaaattgaa tcccaattaa aagatcgagt gaaaaaacta tccagtgatc
    12061 aactgaagct aatttctaat ggagaaacaa agacaattga tcaacaaaca ggtgtctttg
    12121 aattctcggt agaagtacag gcaaatcaga aacaagctta ttatattgtc aatgaatcaa
    12181 gtcctgaaaa catttctaat agcgaggata ttttgctatt aacacctgtt tctgataaaa
    12241 atggtgaatt cttaaaggat gtgtggattt atcctaaatc agaagcttcg caacctaaag
    12301 aagaagtaaa aaaaatcgta tctactggcg taaagaaaaa cttctttgag aattgttggg
    12361 attttgttac tcacttgttt tctagagatt aaggaagaaa taaaatgaaa ctgatcaaat
    12421 tattattatt caatttttct tgtttaaccg cagtcttttt gtactgcggt ttattatttt
    12481 ctaaactatc tattttgcca agctaccaac tatacctaat gaggatttta aacataccag
    12541 ctgcttccat gccgctagat attatggaaa agctcattag gaatccatta tttactacga
    12601 tcaatttgat cgttattgtc ggaatttcac tagtcattta taaaaaagag gggatgaagg
    12661 gatgaatttt aaacactcgt ggacaagacg gttaaaatat gtttttccca taatgatgat
    12721 gttaggtaca ttgtttgggt taaaaacagc caatgtcttt gctgaaaaag ttattgtcga
    12781 tccgtcaaat ccaatccaga acgtaaagaa taattttatt attccaaaag atgttcctaa
    12841 tgcaaaaaca aatattactg taaacggagc gtcaaaagtt tacaaatatc atgttgatgc
    12901 caacaaaggt ggttttacag acgactacgt aggattagtg gagggaaaca aaaatatacg
    12961 ctatccttct ttccaaaaag aatacggtga aacaaacctt gttttagaag gcgtaacaac
    13021 caacaccaaa gtcaatattg actatggaaa aatcggtacg tataacggga aaaaagtcaa
    13081 tatcaagcta gttctatcta atattcactt atactcggat acgttgccgt ggaatctact
    13141 agataacaac tatacaaaaa ctcattttcg agacgatggc tataaaaata cgaatggtgc
    13201 aatgagtaaa tctaaaaaaa gaacagtact ttggatctca gacaatcttt tctcaggaat
    13261 tgtttaccat tcaacacaaa tgaatgtgca gctagtagcc acatatgagg acggtagccc
    13321 cgttcaattt tcaggagata catttatcag ttttaactct ttgaaccctg caggaggaaa
    13381 aagcacggat cttaaaggag aatatgccca ctatgacaaa atgaatacga cagattggta
    13441 tgtcagaaaa gatacggttc tttcagaatt taaatctttc tacaacaatc tgaacgtggt
    13501 aggtggccac ccaggaggaa gctctaagct gacacaagcg gataatgatt tcaataattt
    13561 gcatgataaa ttaggagatc cgaagtttgg tcaaggtact gtgtccttta aaatatctga
    13621 agcaaatccg acgtttgtga ttggttcttc taatgttcaa acctggttta ctttatcttc
    13681 tgcgacaatc tttagtgttg ttcctgatca acctgaaaaa acaggggttg ataaaaatgg
    13741 aaataacgtg aacgataaaa tgttgcaagt aggagacacg attcaatatc gaatcaaaca
    13801 gaaggtgaat cgattaggag tggatttact agcggtttac gatcgatttg agttaatcga
    13861 taatttacca aaagaagtaa attacgtcga tgcacacgtt gaaagtggta caaataaaaa
    13921 attcgatgta tctggtgaag tgacctatga caaaacaaaa caccaggtaa aatatgcagc
    13981 gaaagctgat acattaaaaa atcgaatgaa gtataacggc gaaacttacg aattagtgat
    14041 caatgtaaaa gtcaatgaat tggccaatca aaatagtgta gccaaaaatc agggaacgtc
    14101 gatcattaat aaagtagaaa aggatacaaa tatcattacc gtttatttcc ctaaaattcc
    14161 agtgaaagaa gtacaacaaa atggaaaaga tgtaaacgga cgaaatgacg gtaagaaggg
    14221 tacgccgaca gctcctttaa acgcaggatc tgaagtacaa tatctagtca cacaaaaatg
    14281 gcacacaaaa ggcgtagacg ctgcgtcaga tcactacaaa caatttagta ttcaagatcc
    14341 aattgaagct cgtttgacat ataaagaagg ttctgcgcaa gtaatagata agagtaaagg
    14401 aaaagatatt acttctgaag gcacactaac ctatgatagc aattcaagaa cgctgaagtg
    14461 ggaagcttcc gctgacttct taaataacaa tcttttagat ggacgagaaa ttcagctgat
    14521 atttacagct aaaactccat tacaatcaga aaaaaatatt gataaccaag ccgtagtagc
    14581 agtagataat gtttctaata aaacaaatgt tgtgacaatt ggggttgatc ctaacttgcc
    14641 acaagttatt gttcctaaaa caggttctac acatttagta acgattttag cggtcagctt
    14701 actattactt gtgttagcaa cttttggcta cgcagttctg aagttcaatt aaacaaaaaa
    14761 acaaggctga aaatcagcct tgtttttcta tttgaaaatg ggattggcac taataaatac
    14821 gttgtctgaa gaaagtgatc cgtctgcaga aacttcataa gcatgggata aaccaacgat
    14881 actttgattg ttgtaaagca agtttgcgtt atgagcagcg ctatctttcc acataaccat
    14941 agcatttact gctcctgtat ctgaaaggat ctcgtcaacg taaaggtaga aactattgat
    15001 attttctcct ttagcaccgt agcagcctaa gctttctaag agatcttgga aagtaccgcc
    15061 gccaggtcgg taatgactga agcttacttg taattctttt gcacgaatat ctgcagcttg
    15121 ttgaacgata tcattgaatt gcattggggc aacgccattt tgttgacggt agctatttaa
    15181 ccaagcaagt tctttttgac gcacatagtt gtttaaatca cttagtgaga tatttttgta
    15241 tttgaaagtg atcgttcgat tttggtcaac attattgatt acacgttgtc catttttatc
    15301 aacggtaaca gatgaatcgt catttctaca caagaagtag ttttgatcgg tcatattttt
    15361 ccaagaagta gagaaactat ctccctcgta aaccgtttgt gtttcagtag ataaaacagc
    15421 gtttgtgtca acgtttatat ggttcacagt gacgttgtat tgatgagtat aggcaaaatt
    15481 gattccttga ttacttgtaa cgttgtttaa agtcacagtg ttgctagagc tttctctagg
    15541 atcaagaaca aaattagtga acataggtgc ttcaattgtg atgctttgtc cataaacgac
    15601 gggataactc ttactgtaat tatagagttc ttggatattt ggatcagtat ccgagacttt
    15661 atttggacga gctttcactt caactagaaa gacttcatca tagtaaaaag taaatgtggt
    15721 atttgtgtta atcgtttgtg tttgtgtttc attcccattt acttgatact gtggtgcttc
    15781 aaagttagtc aagtcggttc tagcttttgc agtgtaactt gtaccagctt ttactgagac
    15841 atgttcttct tttagcagcg ttccagtttg tcgattcata tgacggacag ttaccgcata
    15901 ttctgaaggt ttaggtttgt gttgtaaccc tttaaatgca gaatcaagac tatttttagc
    15961 attatttact tgggtttgag aagctttaga atcgtctagt acttttttag cattggataa
    16021 agcagtctga aaattattcc aagatccttc tgtaaaatct cctttagcag ttgattttac
    16081 ttggttgtac aaggcttgta attccgtttt gttcacagta ggagctggtt ttttctttaa
    16141 tcccttgtaa gcagaatcta atgtgttttt ggcactatcc acttgttttt gagtcgcttt
    16201 tgagtcattt aacacttttt tagcattgtt taaagcggtt tggaatgcgt tccaggtatt
    16261 gtcggtatag tcaccttttt tagttccctt aacgctcgta taaagagctt ctaaagctga
    16321 tttattcact ttgggtttag aggtgtcagc accataccaa ccaatacctt cgtatttcca
    16381 gccatagtct ttggttaacc attgtacttc tttccaactt gcagtgtagt gatgcgaacc
    16441 agaggtaaca cctggaagga aaaggcggta gatcggttta ttattttttt cggcagaacg
    16501 ccaggcaggc ccttcataag tccaaccgta atttttggtc aaccatttca cttcatccca
    16561 actagctgtg taatggtgat cacgaaggcc tttattgtat aaacgataga caaggtggcc
    16621 accgctagtc ggtgcttccc aagcggggcc ttcataatta ccccacttaa ttttcactag
    16681 gtgatcacgt tcttttgtgc tagaggtgta aaaatgttca tggttatttg gattataaag
    16741 gcgatacatg acgttagttg aagcagcgtc agcagatcca gcaagagcaa ctgtggcagc
    16801 aaatgttcca atagctataa cagtttttgg gtttaataat ttcatgtttt caactcccta
    16861 ttaaatgatt aaatattttg tttacattca taatatacca cggtataccg aggtagtcaa
    16921 cggtataccg tggaaatttt gaaataaaaa agccgcccta tgaagagtgt aaggatggct
    16981 gtttatatgc tatgaagaaa tggattcggc gtatttggtt agtttggcag cattatcaaa
    17041 tcgcattttt tcaatcgcac tttttttctt tattaaatcc gcaattgttg attctgcgac
    17101 tgaagaatgt ttgctaattt catatgctgt cttgccagtt tcaaatagta accattcgat
    17161 tttctcttta tcagcgtaca ttgcaatgct ccctcttgat tttttcttta ttatagctct
    17221 tttttgtaat aaatcacaat atcaagagga aaagtttcta tagaaaggtg ggaaattatg
    17281 agtatccgtt ccccgtgtat caaaatgagg tttgttgcta ctttcgttat ttaatatact
    17341 aaaataaaac aacgaaagaa ggaatagaat gaaaaagtta ataatggtat ttacttcgtt
    17401 gattgccatg attgttattt taggtggatg tggtagtgaa aaaaataagc aagatagtca
    17461 agataatggc gtgttaaaac caggaacagt gtggaaagaa gaagtaggcg gacttgttca
    17521 taatttaaaa attatagatg atacaacatg ggaatattcc gaaagtgttt ggcatcctga
    17581 acaagtacaa ataacagttg agaagctaaa agactataaa ggattagaaa gatataaggt
    17641 aatcgattca ggtggagtag atttattcat aggtaaaaca gccttaatag tttcctataa
    17701 caaagacggt ttagaaacgt ttaaatttat tccaacaaac gaaaaagaac atcgagataa
    17761 aagtgaaata ttaaaagaat acagtactaa atctggatac aagttacaaa agactagcga
    17821 gtgattgcta gtctttttat ttatcctgaa ggaggaatcg cagtggcaaa agctaaaacg
    17881 ccatttgaaa aagccgcgtc taaaatctta gaacgtcgcg gtgtatctga aacacagtgg
    17941 aaacaagaag tccttgaaaa agcacaattt gacctattac ggggaaaaga caaggactta
    18001 gaaggatata tctatcaacg tgaacgtgaa aagcttgttt tcgatgaaat tattaaacac
    18061 taaaaggagc gaacaatttt atgtttgaat caattacaat gaatttttta acacaaccga
    18121 aagtagtagc tgcggttgat atttttagag cattacaagg tgcagcaact agtttaaaaa
    18181 acaatctgat gatttttgcg gctgtagctg ccgttgcctc cattgttctt ggggggattt
    18241 tcttcttctt tggccgaaga ggagctgaaa acgggaagat gcacgtaggt tatgtattga
    18301 tgggggtagg agttatatta gctgccgcct ctattgtggt ttcgttattt ggaatgtttg
    18361 gacaaacccc acagggacta taaaaaataa atagaaggag taaaaagtac gtggctactt
    18421 tttactcctt ttttatgaaa ggagaatact catgtacttt acgatttcag gcaataccaa
    18481 aaaagataaa gagttaataa aaaaagcaac gaagaaagtg ggaaagcgta ctgccttttt
    18541 accgaaaaca attaaatatt ctgtcattga aacggaagaa cagctacatg tgttaggaca
    18601 agtgttagaa caagagaatc aatcttctgt taaattgact ctcacgttac atgataaaga
    18661 aggaaaaata gaaaaggctg gcacagaata cgtttttggc ccactggatt atcaaatttc
    18721 agaaggtttt tatcctacat tgatggattt gatccgcctt gatgtgttta aggaaacgga
    18781 tgaaaccatg agtgtggaag agtcttatcg aaacgaaaaa ctgctacaag ttttagaaga
    18841 agagttagag agcgaccaaa gaaaagtgag tcaagtgagt gaagtcgaag taaatgatga
    18901 agtaccatgg gaacgaccaa tctttccaaa gaaggagtca aaagaaaaag agacagtcta
    18961 tgttgacgaa caagctgata ttccgactca gaaatcgata tttgaggaag agaacgatgt
    19021 aatgggtcaa ttggaggtag atccctttga agaaacaatg gaggatgaag agacggccga
    19081 agtagaagtt gatctagttg aagctaatga agagccaaca tggactgaag gggattctca
    19141 ggaatatatt gaaccactta tcagtgaaga agtagagaaa aacgaaacag agatacaaaa
    19201 ggcaactgta tttgattata ttttggatca atatccgcca gagcatgaat ggatgaaaga
    19261 aaaaaataaa ttatttttaa atgagcttta ttcgaaatat caattacccc aaacctatca
    19321 agcattttta gagagtaaag aagaattaat ctcacagggt aaaggcacac ttttagaaca
    19381 gttagagtct gttcaatcaa caaattggca tgagcttgca caagaagatt tattagccac
    19441 ttttgaagaa cgtcaacaag aaacagatca agaaataaat gagtatgcga cggaacagtc
    19501 atctaattgg gagagaacaa aagaggaact aaataaagaa gaacaacgag tgattgaaga
    19561 agaagtacaa aaaattaaag agcgatacga aaagaaacgc gacaatgcgt attccttgtg
    19621 tatagagaaa attaataact ttactaaaac taatcaagaa gctttatcga aagaaaaaga
    19681 aaacttgtta aaagaacgta taaaagaacg aaaagaagag ttctaccgag gtttacgtac
    19741 agataagcta aagattagca aagaattaaa tgaacaactg aataaacttt atcaaacaac
    19801 gactgaagtt cttatggaaa gacacgggca gatccagcaa gaattacaag cacaaattcc
    19861 aaaatggaaa aaagagtatg aaattcaaca acaagaattg aaagaacaag aagaaaaaca
    19921 acgacaagaa gaaaaagagc gcgaacaatt agaactaaaa aaacgtgagc agcatcttgc
    19981 agaacaaaaa gtggcgatag aaaaacaacg gttagagcaa gaaaaggaaa aagaagcagc
    20041 tgctcgtaag gaacgtcaag aacaaatgga tacattgcga caagcacagt tgaattatct
    20101 agcacaacct caaccagtag ctgctgttca aacgccagtg aacaaccaag caaatttaac
    20161 tccttcacca cagcgttcct ttaacggatg gatggtggga tgtattgcaa gtttaagctt
    20221 gcttctaggt ggaggaacag tatttgcttt taatcatatc aatcaatctt cacaggcaga
    20281 ttctgtagcc acaacggcgt caatcaagga agaagcccag gaacaagcaa gaaaagagta
    20341 tgaacaacaa ttggaagaat tattgaatcg taccaatcag tcaacagcag agtcaagtat
    20401 ggaaaatagc aaagagagtg atcctagtaa ggctaaagaa ggatcaagcg attcaactgt
    20461 acactcaaac acttccgaaa gttcagaatc aaatgaggtg aaataatgcg tattagagaa
    20521 acaacgagac gaaaagacaa acgattcaat ttagaaaaga ataggtatct ttctcatttc
    20581 tatcgctata ctccttcagg agaagagcta ccagaaaaac atgacaaacg tatttctcaa
    20641 aagatttttt atagtggctt agcttatctt cctttaaact atgttgttac aagaatacca
    20701 gaagcatttc atcgatttga gattattcca ggaagtttac aaggagtgaa tatttttcag
    20761 ttacaagaaa tgccgcagtt attccatttt gattcaactg gtttttggaa tcctttgacc
    20821 ccaacaacaa gtttaggcac acgtttagtt gtttctacga tttgtgttgt tccagctgta
    20881 cttatgggat tgaaaatgga catgtggttt cgtccgctag cagatgggca aaaaggagat
    20941 aaccgattaa aaacgttaaa ggaaatccaa caaatttatc cgcaaatacc agaatcaaag
    21001 ggaagttttc ctggttatgg cggaatacca attactcatt ataaaaaata ctggtatatt
    21061 cagacggata cagtaaatac ttgtattgtt ggtacttccc gctcagggaa aggccagata
    21121 gaagttttag caaccattga caatttgtcg cgtgcagaaa gacaaagttc aatggttgtt
    21181 aatgatccaa aaacagaatt atatgttgct agtaaagatg aactagaagc tagagggtat
    21241 gatgtgtatg cctttaatat caccgatcca ctgcaatcaa tgagtgataa tccattggca
    21301 ctcattgtga aatactggaa gcgaggagac atagacaccg caacacagtt aaccaatact
    21361 tttacgaata cgatttatta tgatgcaaat gcttcagaca ataaatactt taacgaaaat
    21421 gcgcagaaag ctgtcaatgc gcttattttt gcgttattgg aacaagcgga tcaaacaggg
    21481 gattactcca aattaacacc aaataatctc gttgaactac tttcagaaat tggcggtttt
    21541 aattattatc cagatcctga gaatgaattc aagcagctca atgccttaga tgagttcatg
    21601 aatcagttac cccctggaaa tatagcaaaa aaacaatatg gggcaacaaa aattggatct
    21661 gataaagcga aagggaatat cttgtctacg gcaattacag gattgaatcc atttacccta
    21721 acgaaaattg cgaagatgac ttctcaatcg accattgatt acaagtccat tggttttccg
    21781 aagtatttgg atctcaaatt acatgaaagc ctattaaatc aacgcattgt cgtggaattt
    21841 tatcataagg gaaagaaatt tcacgaggaa cgagtcaaag ttggctatcg tggtttttgt
    21901 gaaatcaact ttgattgtca tttagagcag ggagatcatg tttgcttaaa atacaatcat
    21961 caaggaaaac aatatgttgc ttggtatgag ttttctcaaa aagtattgaa agacgaagag
    22021 ggaaaaatcg tttatcgaaa aaaacgagga gaaactcatt tgccagaact agaaaaagaa
    22081 gccgttctaa cattagatga gaagaaaagt aacctattag tagagtctat tcggatgcac
    22141 tataccgata aaccaatggc tatttttatg ttaacgcctg attatgatcc atctaaccat
    22201 atcattgtta gcatctttct tagtcagttg tataaagaat tatctacgca atgtgttaag
    22261 actaaaggag ataaatgtca ccgtaggatt cattttattt tagatgaatt tggaaatatg
    22321 ccaccgatgg acaacatgga aggaatcatg acggttacgg caggtcgtaa tatgttatgg
    22381 gatctgttta ttcaatctta tcagcaactt tatgcgaagt atggagaaca aaacgcagcg
    22441 attatcaaag aaaattgtca gacacatatt tatattatgt cgacagatga taataccatc
    22501 gaagaatttt ctaaaaaagt ggggaataag acggttgaac aagagaacag taccatcaat
    22561 tcattaggta tgaatactca tatcaatcgc aatgttgatt cagatcgtat cttaactcct
    22621 gaaagaattt ctactttttt agaaggtgaa acgattgtac tcgctccttt aaaacgacaa
    22681 gatttgaaag gtcataaaat acggccgtat cctattttta atcatgggga aacgaatctt
    22741 ccttatgctt atcaatatat tgaagatttc aatccatcgt gggatatcaa tgatatagac
    22801 atacattgta cacatgcgga cttggatctt aaggctttac aaattgatta tgattatttc
    22861 ctaccagatg aatatgctag aaatctctat catggactgc atgatcaatt agaagaaaaa
    22921 aacgaagaaa atatgtttta taaaatcgtt caatcttttg agaatgagac ggctaaaaaa
    22981 ttgttaattc aattttacga agaacaagca acggatcgtc ttcaagaata tgttgaaaag
    23041 ttgatcaaaa atgaagaaat ttctgaaatg attaggaaac ggctgttatt ggaagctgaa
    23101 aaggcggtga aagaatgatc attggaggaa ttttctctgg catagccgac tggtggtcag
    23161 gtttattcgg agaaggggat gcagatccca aaaccgtaac gaaagtctta caagattatg
    23221 gtaattatct gcagtatcaa gatgtattca gttggatttg taatactttt ttatggggat
    23281 tgatcaaagg gttatataat ctcaatactt tattagaaaa aacaatttat caaagctttg
    23341 atttaaaaga cttattgaac gccgctggtg ttaatgaact atttcaaagt ttgattagta
    23401 aggtattggc tcttttttgt gtcgtcacat taatttattt aggcttgaaa ttttttatga
    23461 gtaaacaccc accgaaagtc aaaaatatct tggttaattt atttatggcc atgatcttga
    23521 tttttggtgg tagttcttta atcgatgaag ggttaaatat cagtaaaaac ttttatggag
    23581 acgtcactgc agcaaataaa gcagataaaa cgggttcacc tgcttttcaa attattcaaa
    23641 ataatgtgat tgatgtcagt acattactag cgactgaccc gaataaagta gaatccttac
    23701 caacagataa aagaaatgct ttaacagcga aaaatttcaa aacagcgaat atcaatggga
    23761 ttattacacc tgatcaagct aagaaaatgt ctgaatcaag tgatattagt acagtacaaa
    23821 aagatcggtt aaaggcatta cagtatcgac tagagttaga cgataatggg aaagaaatcc
    23881 ctgttcaaat tagtgatgaa ggtttagcaa aatatgtgta tacgtcaggc tatcgtcgat
    23941 acattagtag tccagggatt attttggctg gggaatcttc tttgtcggta gcctatttat
    24001 ttattttgtt tacaatcgtt acttgcatta ttgagctagt atttaaaaaa ttctatttag
    24061 taattgccgc gtcaacggac tttgagacag gacaacggat gaaaagtgcg atagaagata
    24121 tttctcaatc cttcttgtta ttggcgttta cgattttaga attacgaatc tatacattaa
    24181 tgctttcagg tatcggtgat ttgcatgcgg taggaaagat caatggattc ttgtatgttg
    24241 ttgctttaat tgtgctaact attgcgctat tcaaaggctc tcaatcggtt acgaagattt
    24301 tcggtgttga tacgagtctg aaaaacggca gcaattctct tcttagcatg tttgccttag
    24361 gaaatattgc gaaaaatgtg ggtagcggag ctaaaaacct tgcaagtgct ggtaagagtg
    24421 gtttaagcca tttaaatgat attcgtaaga atggatttgg ccatcgaaaa gatattaccc
    24481 atgataacgg ggaagaacaa tcagacgata aagctacaac tgtacctaat agtaagaaga
    24541 cagtttccga aatgttcggg aaagcgaaaa atggtgtttc taaagccgca gaaggtcttg
    24601 gttacgtcaa tgaacgtggg ttaaaaggaa cagttgaaga tcttacagaa aaagccaaag
    24661 acaccttaga agagaaatta gacggcacga gagctaaaga atttgctgaa gctgtgaaga
    24721 atccatccga agcactagaa aaacaaaaag aaaaagcttc agcagtcaaa gaaggactaa
    24781 aagatgcgta tggtgaagga caagtcaatg cagcagtgaa ggcaaataca acaagtgaaa
    24841 aagaaaatca agaaggtgca gcgattcctt cagccaaaga tcaccaagat gagttacatt
    24901 ctaacgaaaa ttcgatcgga gaaaaagatt cagaagaagg acaacatggt cagttaccaa
    24961 aaaccgatcc agaacaatat cgttataaat ctaacattaa ttctgaaaac gaaaaacgca
    25021 tttcagattt accaaaacga aatcaagaag tacaaacgga tgaggattcc atcgatctgc
    25081 caaatgataa tggcatcgaa gttggaactg aaaaatcaac gaaaattggt ttgcctaaga
    25141 cacaaaattt accaatgaaa gatagtcgtt tgaatcaatt caaagagaat gatcaaagct
    25201 ttgttcatca atcacctgca ggtactgttc aaatgaaatc aagtcgtttg cctgaaaatg
    25261 gaaatctgac aactgtttct tacaatttag ctgaaagtgg tgaaacagag aatgcgtccg
    25321 ttcaaaatat tgtgacaaaa gaagctgcac ctaagccaat caataaagtt cataatggat
    25381 acagaccagc aaacgtagca tttactgcac cgacaaaaat aaatgtgaca agagaaacta
    25441 aaaacaggaa caatgaattg aaagaacaac tattgaagga tatcaaacca taaaaggcct
    25501 atttaagggc ctttttcttt ataaaacaag tttaaaatgg aaaggagaaa attgtggagg
    25561 atattttaat agctacgttt ataactgcac tgggagcatt tttaacgata tttgtggtga
    25621 ctattaaagg atttaaagat acggatagtt tacaaaaaga tcatcagtct attttagatg
    25681 gtcaaaaaac acataccgaa agcattattg tacacctttc agaaggattc acttatttga
    25741 aagatgctat gcccacattc acagtaaaat taacggaaat atttcattct gttgagcaaa
    25801 tatcgtcaga attgaaagag caaagacaac aaaaagatcg tcaacttggc tcacttaatt
    25861 ttaggcaaga aacgatacaa gaatcattgg agaatgtaaa tcgattaaac gatgaaatgc
    25921 aacgagttca tttggaaaat gaagaattac gcgcacaaaa ttatgattta attcaaaaga
    25981 aaagaaatct ggaacaaaaa attgttgaat taaaagaaga aaatcgtcaa ttgaattatc
    26041 aattacgacg aggaaaaaat cgttctcgtg atttaggaaa tgaattagag ttgtaatatt
    26101 tagaaaaacg ctgtgagaaa tcacagtgtt ttttatttct aaaaatacaa aatataaggg
    26161 gtatggttat attatggata aatacattca tatgaaaaat cctccaagat ttagtgggga
    26221 atggaagttt ttcgcctttt tctttttaga tctattaacg cttggtggct gctttttttg
    26281 ggcgaaaata gtcaataatc ttgtccactt accactcttt tttgcactct tgaattatgg
    26341 attatggctt gcgatagcgt tagtgattgt ttggcgaccc tataataacc ctggtcaacg
    26401 ccaaattttt gcgattatcg aatctatttt ctttacggat aagaaccact atcatgcgtt
    26461 agatcctaac cgaaattatc atggtacgta taaggaggat gaataaatgc gagtcaaagg
    26521 acaaaattca gttgataaga aatccatttt gcagtttgga aaaccagaag agcgctctat
    26581 cttggactta tttccatata aatcctgtac agaagaggga gtcttaatta ctagagaaga
    26641 tcattttcag cgttattatc gtgtcgtttc cactgacgtg gagggattaa atgaacaaga
    26701 gaaactagaa cgaatgaatc agttgaccac cgtcatgcgt acgtatgtgc caacaattaa
    26761 gttagttagt ttgaccacag agacggatct aacggaacaa atcgtgcaaa agcggcagtt
    26821 attagataaa aatcgtatgg aacagtcact aggaagaaat ctacagcgat taagaaaata
    26881 tgaaaagaaa ttagtagagg agatccagga attaaaacgg gcagaacaag aacgtcctga
    26941 cttaagcttc tttttcgtta ttgaaggaaa gacaatcaag gatttacaaa ctagaaatcg
    27001 tcagttaatg cgatctagtg gcattttagg gttaaaacca ctctacaaaa aagaattgat
    27061 taagattctt tatcgaatga acaacatgaa tgacgaataa aaaagatgga ggaaatgatt
    27121 catgctagat gtgataaaaa cagctttttc aacgcaaagt aatcaaaagg tgattgatcc
    27181 attaaaacaa cttggtaatc gtgaaataga gattttaaaa tcaaaaggtt atgatttaga
    27241 tttcttaaaa caagtgatgc cacaaggtgg gttgaatttt gatgaagaat atgtgaccta
    27301 tggaaatggt tattcacgat gtgtgacagt ttatcattac acaaaaaatc ctactctttt
    27361 ttggttggcc aatctcatga acaatcctca tacagtggcc acactagatg ttagcacaga
    27421 tgaaaagcaa aaagtgattg atcaaatcaa ccgcgcatta gatgaattaa atgatcgatc
    27481 agataatgaa cgaaaagcga ctgaccgaaa taaaagtgcg gaagaatacc tggaactagc
    27541 ggaatatgcc cgaaaattga cttctaatgg ggaaatttct aaacaagtca aagtgagagt
    27601 acatgtttac ggaaatacga tccaagaagt ggatgaacgg gcgcaggaac tgatcgaaaa
    27661 tctaaaaggg atggattatc gtgcggtgac ttatctgcat aaaaccaaac gagattggca
    27721 atcgatgttt accatgttcg atgaacaagc tgaatggttt ggaaatatca aagggcaatc
    27781 acttccatcg ttaaacattg gcggaggatt cccgttccac caccaaacgc taaaagatcc
    27841 aggaggcaca caatatgggg aaaccatgac aggcggccca tttgtctgga atgccacgta
    27901 taaaaatagt gtacgtttat ctaccaatac cttgcttcta ggaatgatgg gagctggtaa
    27961 atcgaccgtt cttaaaatga tcgcggaagc ccatttagct gcaggagact ttatttgggg
    28021 ctttgaaaag ggaaaagact ttattccttt cttaaaggaa tataacggta ttatggtgcg
    28081 tttagacgga tctgacggga tgatcaatcc tttagagatc tttgccacac ggacgtatga
    28141 tgaagcatcc agtttatatg acgatggttc agtcaaagat ttgaagatca atgaagcagc
    28201 gtcctatcaa acgcacttag acaaagtagt ctatcaggta cagttagtga gtcctcagct
    28261 aaaaggaacg atgaaagcag aattcaagac ctacttgaat cgtttttatg aagagtatgg
    28321 aacagtacca cgcggtttta cttcctcaaa ttcgcgttca aatactgata cgcaagtcac
    28381 agggaaagat ccagaagctt atccgacgtt caaagaattt ttagcctttt taggacaact
    28441 ggaactacca ggggcttccc aagagaaaaa gaatcggaaa gaagaaatgg agtctatcgt
    28501 ggaatcctta tgtgagactt atggcatgat ttttgatggt catagtacga ttcgacacct
    28561 tgaccaacaa cagttggtct tttttgacat tgactctatt acaggcctag atcgaggggt
    28621 acaacaatgt cagatgtaca tggccatgac gttgatttgg aatcaggcat tgattcaagg
    28681 acgaagacaa cgacgcttaa ttaaagaaaa acaaatggaa gaacaagact tcaaacgctt
    28741 cttggcgatg attgatgagt gccataatgc gattaatcca gatttcattg aaacggtaaa
    28801 ttatgtcaca aacttccaac gagaaatgcg taaagtagaa gcaatgactg ttttagctac
    28861 acaatcccca caagaaatgg tgccagaaaa tatgtcttct gataacttct cgaaactgaa
    28921 gaaagtcttt gaattttctt ctacgaagat ctttatgcgt atggatgaat ctattttacg
    28981 tcatatagaa ggattagttg gtaaatcaat gacgaactca gaattagaat ccattcctca
    29041 acaaaatcaa ggagacgctg tgatcaattt tggctcaaaa gaaaccattc gtgttcattt
    29101 tagtccgaac aaacgtcaat taaaattgtt tgatggagga aaataatgga aaaccaaaat
    29161 gaaagtttaa tcaaacagta tgttaagcgt cgtgcaaagc ggcgcttatt tttgtgggtg
    29221 tttggtactt ctgcaggttt gattactata ttgatcactg tgtttgtgac cctttttcta
    29281 atacttgcgg caggttctat tgataattct gattcaagta gtggtggcga agcttttaca
    29341 ggagaatatt cggaaggctt acccatttat aaagaaatca aaggaagagg ccctttttct
    29401 gatgagattg cgcaatatgc tgtaggtgca gcagtgaagt ataaattatt accaagtgtg
    29461 atcctttcgc aatacggtta tgaatcagcg tttggtacgt cggcgtccgc aagaaatgat
    29521 ctcaattatt ttgggattac gtggtttgat gggtgtctgt ttcctaaagg aactgcgcgt
    29581 ggaattggtg gcattgaagg tggctggtac atgaagtttc ccaactcaaa agctgccttc
    29641 tcctattacg gctttatggt agccacacaa tcaaatttta atgcttgtgt cggaaataaa
    29701 agccctggcg caagcttatt gatcttagga cgaggagggt atgccgccgc aggaattact
    29761 gaagacagtg cctattataa aaattgtatg tctattatta atacaaataa attgatggag
    29821 tacgatgagt ttgcgattaa acactggaga gaaggcggcg gaactggtgg tacgattaca
    29881 ggaagctggg gcaatccatt cccaggaagt agcttagata aaaattcgtt cagtggagga
    29941 caactttttg ggaaaaatcc aggaggagaa ttccgaccta acgggttcca tgatggacta
    30001 gactttggtt cagtcgatca tccaggaagt gagattcatg cggttcatgg cggaaaagtc
    30061 gtgtacgttg gcaatcctgg tatttcaggt ttgggtgcgt gtgtgatcgt gattaattac
    30121 gatggcttga atatggtgta tcaagaattt gcaaatagta caggaaattc tcgagtgaaa
    30181 gtaggcgatc aagtgaaagt tggtcaagta attgggatac gagatacagc acacttgcat
    30241 ttaggattta ctcgaatgga ttggcgtcaa gcacaaggac atgcattcat tgatgatggt
    30301 acatggatcg atccgttacc atttttgaat agcagcaaaa aatagatcag gagaaaaaat
    30361 atggaaaata aaaccttaaa aatcgtctta acagctgcaa ttagcgttag tttaatcggc
    30421 aatattgcgt tgttttggca gcttaaagaa gaacaagaga caaataccta taaaattgaa
    30481 gaagtggcta aaaacgcgtc tgataagctc aaaaaaaatt cttctgaagc acaggcgaag
    30541 attgacaagt taaatcaaac catcaatgag aaaaaccaag aaatcgatca gctgaagcaa
    30601 caagatggca caaaagcaaa agaggaagta actgaagcac aaagaaagac ggcagaagag
    30661 ttcggtcaat tggccattga taaatcatta agcagaaatg aattaacgga aaaactaaaa
    30721 gatgtcgcaa cccaagaagt gatcgacaaa ttaagtcctg tagacgatga tcaccaacat
    30781 gatgattacg gaagttactc ttttacatta ggtgacgtgc aaacttacgc tcaaacaagc
    30841 agtgtaaaag aggaacaaaa ttttgtcgta tttgttgatt atacaatcgg caatcctcaa
    30901 ttcaaagatg tcaaaccaca aaaaataaaa ggtggattaa ctgtcactga aaaacaagta
    30961 gatggtcaat ggaaagtcac agactttagt tatttcactc gttaggagga agaaaatgag
    31021 taagaaaaaa ggagcaagac aacgttttaa aaaacgaaaa agttatctta gatggctggg
    31081 gatctttatg attctcggct ttttgattct tgctagtccg atttacacac ataaaaaggt
    31141 agacatacca gatgaagtaa gcacgaacgc atttttaaac acgaaggaac tgacgatggt
    31201 ttcaaaagaa aaaggagcga accagcaatt agtttttgaa tttgcgatcg acgatgaaga
    31261 tcagagctta ttaaaagaac tagctaatct taattatcgt gtagaagtaa agacagctaa
    31321 aggggattat caagcaataa aagccaaagt gatcaaggtg tctgatgatt attttgtagt
    31381 gaagttagca catgtaccag aagaatatat tgctatgcga ttaactatta ttcctgaaaa
    31441 aattgatcca aaggtggata tgcaagaacc gcaagatctg attttttata ttcacgaaga
    31501 taaggtcaaa gatcacgtga aagacgaaga ttatgaacaa catgcgatca attacaaagt
    31561 gaaaggatac aagaaagaac aaaaagcagc acaaaaacaa attgaatcct tccaagcaac
    31621 cattgatttg aatgaagaat tagtgaagaa actaaaagat caattgcctt atcaagtcgc
    31681 agaagatcag gaaaatactg aaaataagat taatagttac cagcaagaaa ttgaaacatc
    31741 gaaaacgcaa atgaaagatc aagaagagag cattcaaaaa cttcaagaaa aaattgatcg
    31801 tatgacaaaa gaaaatattt agaagaatag gtggagtaaa agaaatgaag cgagcgaact
    31861 tggtcggcaa agatactttc gctgagcaga aagtattgat taaagcctat ctcaaagttg
    31921 taaaagctaa agaaatatgt caagaagtga attatctaac acaacaatat ctgagttgaa
    31981 gaatggtaga aagagtttag ataccttaaa attcagatca tttgaagctc tatatatagc
    32041 tgctaaaaaa tattttacag ctgataataa ataaaaaatt aaggtgggtt ctatgtgaaa
    32101 aaaacgtatc aaaagttttt atggattagc tatatcgtcc tatttatcgt tgggtttctc
    32161 gtcagtgtgt ccgtgatcgt cggaacgctt tttcttttgt tctctgacga agatctggta
    32221 cttaaggggt taatgagtac gttatcgtgt gtcatgttac tttatttatg tatacagatc
    32281 aacgaaatta tgccccctca ttggcaagaa aagaagaaag aatttaagga agaaatcgaa
    32341 ataaaatcca atgactggat tgaatacaca tggcttcctc tgaaaagaaa tagcaaacga
    32401 aaggaatttt gggcattgca attatggcca ataggaaaac tttttattta tatggcttca
    32461 cttatggtta ctttaatcgg ttatttggtg gtggtctatg gggtggccta ttacttgtta
    32521 agtgagccaa aacagatcgc ggcgtcaaat attttcacgg cagtaatgac attaatgtgt
    32581 gtcatgtgct tttctatttt tagttactta ctcgtccaat ttatcaggca aaatttaaca
    32641 atgagtaaac ttttcaaaag tttattggac ttacttatct taggcagtat gttaacgact
    32701 ctaacagatc ggttcgaaca atctgaaaaa acggtagagg ggataaagaa cttcttaacg
    32761 acgattgatc aatttataaa tggatatatg tatttgtttg aagtaggctt tattctcact
    32821 ttgtttggtt gtgtatttat aaaactcatt aaaagatcaa tcgaaaaaga aatggttatt
    32881 gatctaattc cgacgctgag cggctatgag tattacgttg attttggaaa gtatgaggag
    32941 ttgatccata cggatatcgt tcacacgagt atccatgaag taaccgttaa gggcatcaga
    33001 tctactttaa aagatggaca ggagacgaaa acaatcgacc gaagaaaaga ggtctacaat
    33061 ttttataaag ttgaagcaag tctacgatat ggcattggga aattgaggtt agatgggagt
    33121 aatattcaac aaaacaaacc atatgtttta ggaaaagtgg tgatttagaa cttcctatga
    33181 aagatgaata aataaggaga atcttttgaa aatgattctt ctttacagaa ttgtgcttat
    33241 agttggcacg gagttaaaaa tcttaaagaa ggagcagtta ttcaaagtga aagaacatca
    33301 taatcagtta ctatgtatta aaacgggtac gatgaacatt caataccgaa cagaatattt
    33361 agaattaacg aatcaaactg attttttgtc gattcgagag caacataagc aagaaaaatt
    33421 aatggctact tatagccaat tgattgatga gtgggaacaa ttcaaggaat ctaaaacata
    33481 aaattccatt taaacacctt attttttaaa gagcataagg aaacgtgtac ccactttcaa
    33541 aataaagtgg gtagataggc tgtgcctatc acgtttctga aaaaaataaa tgaccccaaa
    33601 attttcaatt tatgtgtagg tttatgggta gcaaaaatat gaatgtgggc agcaaaaagt
    33661 tcatttgtgg gtagtaaaat tcaaatgtgt gtagcaatgt gtgtagctac acacattgct
    33721 acacacgcta taacatatag tgaaaaggag atatttatgg aagtaaaaat aagagatatt
    33781 gatgaaaaaa cgattcaaag aattgaccga agatgtattg aattaagtga acgcaccggg
    33841 actaaatgga gccgaaatcg atacctaaaa gttttgattg aaaatgattt tgaccatgaa
    33901 cttatggatc atagaaaaga tcaatttgat cggttgttag aaaaatttgt ggatattcaa
    33961 acttataata cgaaaatttt agaagaatat attgcaacaa ataatcaatt aatcgccttg
    34021 ttaattgaat aataaaaata gtattgtgaa tttataaaag gaggaaatca attttggcaa
    34081 aagcaacaag aaaacatgta tatctttacg atatgcatat cgaagtactt gatgaaataa
    34141 tttctactca tgaagatata tctaattata gtgaagcagt cagacatttg tgtatgatgt
    34201 atgatccaaa aatcgaagaa aaaataaatc caattcaaat taaattgaat gcaatgggaa
    34261 aagaaatttc tatattaacc gaaatggttt cagagtttgc ggatcttcat ttgaaagata
    34321 caggaatact aattggtaca aattcaactg tctatcaaga agcaaaagag cgtgtggaag
    34381 ggaaaataaa agcgaatcaa acgaaaaagt attctcctaa gatcaagaaa ccaataaatg
    34441 aatctgttca tgccagagta gacccgtttg atccaacaaa gtttttaaaa agataaaaag
    34501 tagaagggga acatgatgaa taaatcgcct gcagtcattc tcacttgtca atttaccttg
    34561 cccaataaaa aatctttttc aacatacatt gattatatga caagagaaaa agcgctggaa
    34621 gaaaaggaac gacgcacgcc ggacgaagaa caggaactgc aacgaatcaa gaatgcttta
    34681 gaggattttt atattcctga aggagaaact ttttcggaga gtaagacaga taaagaattc
    34741 agtgaaacgt cgaatgaagc tcaatcgttg atggaacatg gaatcaattt tgacaagtta
    34801 gaggaacaag attttaccaa atatctttct tatatgaccc gtcactatgc gttagaacaa
    34861 aagaaagaac tgacgcaaag ggaacaaaaa gaataccaac ggttgaacca agcaatgaaa
    34921 aaatatcaaa cagagccaca taaaaaagct tcaggaaatc ttcctggagt tttttctatg
    34981 gcttcagacg aagtgaaagg aagtgatctg aaggagatca aacaaatctt ccaaagaggg
    35041 caacaaaaag gctcaatcat ttatcaagat gttgtctctc acgacaattc gtatcttgaa
    35101 aaaatgggct tgtacgatcc caaaacagat accttagatg aagaaggatt aaaagcagct
    35161 ggaagaaaaa tgatggagac attattcgag aaagaacaat tgaatgaaac aggttactgg
    35221 atggcaacga ttcaccgtaa cactaagcat atccatattc attttgcagt tgttgaaaaa
    35281 gaaaatacgc gtaaacctta cacggaggtt gaaaatggtg tgagttatat cgtaccgaaa
    35341 ggtaagagaa gacaagcaac attagacgca atgaagacca attatgtaca tgagttagaa
    35401 cgtttttctt atgaaaagga tcgaatgatt ggtatggaga aacgaaattt attgacgcgg
    35461 aaaagtgatt tgcgtaacac cttaacaaaa gtggtaaaag agccagcgcg ttacgatcga
    35521 cacgcaatga acttattaaa tgaagtatat aaaaccctac ctgacaaacg ttcggaatgg
    35581 cattatgggg atgaaaaacg aaccaaactt tcaccataca caagagagaa actcgatgag
    35641 ttaaccaaat atgtgttaac aaaagaacct gaatatcaag aatatataca gatttcaaaa
    35701 tcattgaaag aagaagcaaa aagtctttat ggggaaagca agagagaatc aaaggatgca
    35761 gaaaaaaatg ctctctttga tttgaagaag cgcacaggaa atgccattct aacagaactg
    35821 aagaaacagg atagtcaaat aaaaccttta atagaaagta tggatcagat gcaatctatt
    35881 tacaatgaac gatcctttcg aacgcttaaa cagttaccaa cgaatgaata caaatatagt
    35941 tacgaagaat tcatgaagcg caggaaacaa ttccaacaaa gagttgtcac gcaacggagt
    36001 ttgcgtcaat taaatcgaac gattaatgcc catgaagaaa aataccacgc aagtaaagcc
    36061 tacgaagagc aacaacgaag aattcaaatg gaacaagaaa gacagtaaag acagtaggag
    36121 gaatagcaat gaaacaatat ttagatcaat ggaaagttat agaaggatca ttaagagaag
    36181 aacgaatcga acaacttccc gattgtttag aaaaagagca tttgtttcag ataagagaaa
    36241 tgttgagaaa cgaacagttt gatccaaatc aatttttagt cgttgagtac tcagctactg
    36301 gtgtgtactg ttgtaatcat gtgaagggtg aaaaatattt tatcattcaa gaatatgagg
    36361 gcaagttagc gccttattat actacttggg aaatgaatga agaggggatc aataacttcc
    36421 cgtgtaaaag cattgaagag tctatttcac tcacagaatg ttagttgtta agtgaataaa
    36481 agaagtaaaa gagtcctgaa cgtaattgtc caggactctt tttttcaatg aattgttttc
    36541 cgccaattca atgagtggtg cgatttgcga ctacattata tcaaaagaaa gagaagggag
    36601 gaagaagaaa tggcttattc aacgattgga gttgttgttg aaaaaagcag agacaatctc
    36661 gtttttgtga cagaaattca aacgggcaga gcttttgtcg tcacagacaa agcggcaaaa
    36721 gcgtatcaaa gtggcgatat tttaacgtta aatctgacta cgaagacgtt cgtcgatgcg
    36781 gcagaagatt atccatt
//
LOCUS       DAFBVQ010000023        35796 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.023, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000023 DAFBVQ010000000
VERSION     DAFBVQ010000023.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35796)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35796)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35796
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.023"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..702)
                     /locus_tag="LLC22_001322"
     CDS             complement(<1..702)
                     /locus_tag="LLC22_001322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter ATP-binding protein"
                     /protein_id="HBK5434607.1"
                     /translation="MLEVKKLNVCYNDFLALNEISLKIQEGALTGIIGPNGAGKSTLL
                     KAMLNIIPHQGEVSINNEDINKKLVKIAYVEQKADIDFTFPIKVKECVSMGTYAGMKV
                     FQRIKNAEWQRVSKALEKVDMGKYSNHQIGELSGGQFQRVLLARCLAQNADFIFLDEP
                     FVGIDLVSERIIMDTLKELKHQGKTVLIVHHDLSKVKKYFDNIILLNRNLIAHGSVES
                     VFNEENLKKAYGDTIF"
     gene            1390..1548
                     /locus_tag="LLC22_001323"
     CDS             1390..1548
                     /locus_tag="LLC22_001323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434608.1"
                     /translation="MNKKQTCEFLGIDNNTLDKWIRIYNFPVIRIDGIVRFDIEDIKD
                     FMNTFKTI"
     gene            1620..2846
                     /locus_tag="LLC22_001324"
     CDS             1620..2846
                     /locus_tag="LLC22_001324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5434609.1"
                     /translation="MPTKLSNGKYKTNLRYPKKFREITGITSEKYQKVFPTRQLAIKA
                     ENAMKRKIETVLREENANSLELKGKIKFKEFYESKWLPRYELGQTTRSKRAPSYVTIS
                     NTKDIFRLHILPMFGEYAMNYLNSNTEIISDELTKKSKEYANIKIIKGYVRSMFDIAE
                     ILNYIEFNRTTKIIQCITAPKKIALEERRIREGNQALSSEELIAWIEAVNTDLNNHLL
                     TLHDYTLFMLTLYLGDRKSETYALQWKYIDFEKQTVRLKHALDKYQKKKFTKGRKDTV
                     IQVPEIVMALLSKWKSVQAEQLLRLKINQTPDQYLFTYTKPSGEVNCPVHADYLNYRI
                     NSIKRRHPELAHLSPHKLRHTYATIARQGGANMNQISSALTHSDISTTRIYVNTPDVV
                     DKTVFEAFQRGLNKCD"
     gene            complement(2935..3327)
                     /gene="rpsI"
                     /locus_tag="LLC22_001325"
     CDS             complement(2935..3327)
                     /gene="rpsI"
                     /locus_tag="LLC22_001325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002942223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S9"
                     /protein_id="HBK5434610.1"
                     /translation="MAQVQYIGTGRRKNAVARVRLVPGTGKITVNKKDVEEYIPHADL
                     REVINQPFAVTETKGAYDVFVNVNGGGYAGQSGAIRHGIARALLEVDPDFRLALKRAG
                     LLTRDARMVERKKPGLKKARKASQFSKR"
     gene            complement(3343..3786)
                     /gene="rplM"
                     /locus_tag="LLC22_001326"
     CDS             complement(3343..3786)
                     /gene="rplM"
                     /locus_tag="LLC22_001326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L13"
                     /protein_id="HBK5434611.1"
                     /translation="MRTTYMAKPGEVERKWYVVDATDVPLGRLSTVVASVLRGKNKPT
                     FTPHLDTGDFVIVINADKVKLTGKKATDKIYYRHSNYPGGLKSITAGELRAKNSRRLI
                     ETSVKGMLPKNTLGRKQFTKLNVYGGAEHPHAAQQPEVLDITNLI"
     gene            complement(4305..4772)
                     /locus_tag="LLC22_001327"
     CDS             complement(4305..4772)
                     /locus_tag="LLC22_001327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA starvation/stationary phase protection
                     protein"
                     /protein_id="HBK5434612.1"
                     /translation="MKFQQTKEVLNQLVADLSQMSVVVHQTHWYMRGPGFLTLHPMMD
                     EFMDDLNAQLDEVSERLITLDGSPYSTLREFADNTKIPDEIGRWDRTIPERLETLVAG
                     YRYLADLYQKGIEVSGEEGDDPTQDIFIEFKTATEKRIWMIQAHLGKAPEIDA"
     gene            complement(4892..6430)
                     /locus_tag="LLC22_001328"
     CDS             complement(4892..6430)
                     /locus_tag="LLC22_001328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318022.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconokinase"
                     /protein_id="HBK5434613.1"
                     /translation="MNVSIGLDIGTTQTKAVAFTDEAQEAASAYFRYPLIQETQGMAE
                     QDQELIFQGVCTVIKEVIKQLPSDTIIQFVSFSSAMHGLILLDEEKTPLSRMITWADN
                     RAADEAEKLKYTVLGKEFYRQTGTPIHPMTPLNKIKWLQNSQPELFKKTAYFVGIKDY
                     IFYRLFGELISDYGTASGTGYFDIHEFQWAEEVLDYLNIRIEQLPQVFPSTYQVTGLP
                     SKTAAELGLPNDISFVLGGADGPLSNLGLGAFGDTIAALTVGTSGALRFITTQPQFHP
                     EMETFCYVLDQKHWVVGGATSNGAGIFDWAGHTFLQEVVQSAKEKGENPYDALLSAIA
                     FVPAGANGLIFHPYLLGERAPLWDADAFGSFIGLQRQHTEKEMMKAILEGICLNLYRI
                     LKGVCQENQLTEIRATGGFAQSPIFRQMMADVLGYPLVFPTVTEASALGAVILGWRSI
                     GKIQSISEAQELIELKEQVGVQETDHKKYQKIYPLFVSTQKHLAQTYQQFAQLREELA
                     DSEK"
     gene            6510..7196
                     /locus_tag="LLC22_001329"
     CDS             6510..7196
                     /locus_tag="LLC22_001329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prepilin peptidase"
                     /protein_id="HBK5434614.1"
                     /translation="MLLYFIIGCCIGSFLCLTAQRIPLGHSIIYPRSHCVKCCRSLSW
                     YELIPILSIIVQRFRCRYCRCRLPFYYLLAEALCGGLFAWFFTFSSARNFSTFIWMLS
                     ALLFSLMDLFYFMVHSHTLFCSWAILWIFWLQAGVFQWQSVLLTFIVGGVCLRYGQSY
                     LGAGDTLLMLSWSGGLSLEELLQILFLASLFGISVFSVYFICHKKKLEKLPFIPFLSS
                     ALLIVLHLRY"
     gene            complement(7397..7924)
                     /gene="msrA"
                     /locus_tag="LLC22_001330"
     CDS             complement(7397..7924)
                     /gene="msrA"
                     /locus_tag="LLC22_001330"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339692.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5434615.1"
                     /translation="MTKKAVFAGGCFWCMVKPFEEQPGIISVTSGYTGGHVPNPTYEQ
                     VTTGTTGHTEAVEIEYDPEVISYDQLVEIYWQQTDPTDALGQFADRGDSYRPVIYYND
                     EEERNIAERSKQALQDSGRFDKPIVTKIEPRSEFYPAEDYHQDYYKKNKLHYNLYREG
                     SGRAGFLRRHWGVKK"
     gene            complement(8008..8685)
                     /gene="pgmB"
                     /locus_tag="LLC22_001331"
     CDS             complement(8008..8685)
                     /gene="pgmB"
                     /locus_tag="LLC22_001331"
                     /EC_number="5.4.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-phosphoglucomutase"
                     /protein_id="HBK5434616.1"
                     /translation="MKIKAALFDLDGVLVDTARYHYEAWLVLANQLSIPFTEKENEQL
                     KGISRTESLERLLSFGKMEQKFSEKEKSAFAEQKNNLYLQAIQKMDETSVLPGAIAVL
                     EYLKKTNIKIGLGSASKNARLILEKTNLTSYFDVLIDGTQVSKAKPDPEVFLKGAQQL
                     NVPPNACLVIEDSEAGCQAALAGNMHVLGIGENINLPSAEYVIPDLTVFDQVRSFWHL
                     SEAVSRI"
     gene            complement(8682..9812)
                     /locus_tag="LLC22_001332"
     CDS             complement(8682..9812)
                     /locus_tag="LLC22_001332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBK5434617.1"
                     /translation="MRILIAPDSFKESLTALEAAQAIQSGFQEVFVQAEYDLLPIGDG
                     GEGTVSSLADSLRLKRQTAVVTNAFGKNKEIQYASDGQTAIFEMAEIVGLKDVPLNQQ
                     QPLRLSTRGVGELIRQLLQQGVRHIIIGVGGSSTNDGGIGMAEGLGYAFYDQDNQKVE
                     ALGENLGKIATVDKTNVPIELIKAKITVITDVTNLLCGKEGASFVFGPQKGLKENELA
                     VADQAMHDFYMRFAPQVIEASGSSAGGGMGAGLLAFASGKIVSGIDYVLDLLEFDKRV
                     QQADLVIVGEGRLDGQSLKGKAPVGIARRVPEGVPVIAICGSVGKGSEKAADVGISAV
                     FPILPAAVPLQEALQQATDNLHRTAKNIASLLQVVHFQGGNR"
     gene            complement(9812..11995)
                     /locus_tag="LLC22_001333"
     CDS             complement(9812..11995)
                     /locus_tag="LLC22_001333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 65 protein"
                     /protein_id="HBK5434618.1"
                     /translation="MKVEEKQFDLEYINKYASQMTIGNGFFGIRGSQEEDYRNQVRGM
                     FAAGVYNRPLGAESAELVNLPDVIRWEIKIDGEHFSLETMKVLAYERALDLEMGELKR
                     YALIETAQGKKVEVITCRVADQNNLHQAALKVVIKPLTEDCQVDVKTGIDGQQTNFGT
                     QQLVEKELRVFGDDLISASYQTTESKIDIGIAAKFNKAGVFQAKNRRITASFSEKIRK
                     NTSFTLEKIIVLSTSLQQTDPFKKSIAQAQKSVSYTEILEQSMSYWTDFWHQHRITIQ
                     GDSSFDQLAMDFAAYHLQIMTPRNDPSVSVGAKGLTGEGYKGHVFWDTEIFILPFFLY
                     QFPEVAKNLLLYRYDRLEGARQKARDYHYQGALFPWESAHTGQEETPKFAALNIKTGT
                     RQEVASAAAEHHISADLAYAVQEYVQATEDQSFLETKGKTLIHETAAFWLSRAVKVDD
                     HLEIHRVIGPDEYTEYIDNNAYTNYLAHYNVALAVKYQAGDPLFLKECQNFLDKLYLP
                     VPNKEQLIPQDDTYLSKPVIDLTTYKERPGSQSILLDYARSEVNELQVSKQADLVMLL
                     YLLPEYFSQPIVSKNLHYYENKTIHDSSLSKAIHAIEACRIQEMEWAYHLFQEACLID
                     LGPDPHSSDDGIHAASLGALWLAVIFGFSGITVTNGTLSISPRLPSAWEKISFPFIWK
                     NHRLLFVLTKKQIVIKKETKETLPIFVNGDQYQLEKELILERRGK"
     gene            complement(11992..13017)
                     /locus_tag="LLC22_001334"
     CDS             complement(11992..13017)
                     /locus_tag="LLC22_001334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337111.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5434619.1"
                     /translation="MKKVAIIGAGQVAEKVHAAYYQKRSDVLELAAVVDPVSQRAEDF
                     CRRTGFSHAYTSVTQMLNEISPDIVSVCTPNRFHFEHVLAALEANASVMCEKPPAMTA
                     DQARKMAETADKNGQILAYGFQHRFSDEATMIKNHLDVLGDIYYVEANALRRSGVPGW
                     GTFIDKELQGGGPLIDYGIHMLDTAMYITGFPKVKSVRAYSFQKIGTKKNSGKFGKWD
                     PSKFTVEDAIFGTLELENGKIIQLNTSFALNIREDKLNVAFCGDQAGANLYPGELFED
                     VDGKLVSLQKTTPVNDPHELSMAHFVNRALGDQTQMIADGWQGYVIQNLVENLYRSAE
                     TGEVITL"
     gene            complement(13062..13889)
                     /locus_tag="LLC22_001335"
     CDS             complement(13062..13889)
                     /locus_tag="LLC22_001335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBK5434620.1"
                     /translation="MKFGTQDQAFFPRDILEKFRFIKDCGFEEYEIDGKLLIENIDTV
                     KQAIKETGIPVVTACNGYDGWIGDFIEERRLNGVRQIAEILRALSEVGGKGIVIPAAW
                     GMFTYRLPPMVSPRSKEGDYKAVSESLRYLDKVAEETGTVIYLEPLNRYQDHMINLLA
                     DARHYIDSNQLKHVQIIADFYHMNIEEDDISKALTTQKEYVGHIHLADNHRYQPGSGA
                     IDFTRHFQTLLQNEYEGYMVYECRLRGENEVKIYQESLQYLKNCLETARHLNDLEKE"
     gene            complement(13886..14953)
                     /locus_tag="LLC22_001336"
     CDS             complement(13886..14953)
                     /locus_tag="LLC22_001336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase"
                     /protein_id="HBK5434621.1"
                     /translation="MKKLVALEPRIAGFKDYEDREIEKNEVRIRVIFATPKPGTEIVD
                     FRGLSPFIDEEFSEEWRLFLPREEGSQRGVVFGEFQLGNMIVGTIEETGSLVTEYQKG
                     ELVCTYGPIRETLITNGVDNYKLRKLDRLDQWKNAVCYDPAQFALGGIREAHVRAGDA
                     VAIFGLGAIGQIAIQLAKKAGATTIVGIDPIAQRRELAEKYGADYTLDPMKADVGFRL
                     KELTDKRGVDSVIETSGSAAALQASLRGIGYGGIISYVAFAKPFPAGFNLGREAHFNN
                     AKIVFARASSEPNPDYPRWNRKRIEDTCWELLMNGYLDCEEIIDPVVPFAESAEAYMR
                     YVDQHPEESIKMGVQVRGGEQ"
     gene            complement(14979..15815)
                     /locus_tag="LLC22_001337"
     CDS             complement(14979..15815)
                     /locus_tag="LLC22_001337"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5434622.1"
                     /translation="MKNKKSRKILFYATILLLLAVNLFPFLIMLMTSFKDSQEAIATT
                     QTIFPKEWTFEHYQDIFNAEIFPFIMYFKNSLVISLIASVTAVVIGISGAYALSKLRF
                     KARSKINASFYTVYMFSGILIVVPLFKIISGLGLYDTNTALIITMVVQTLPTAIFMLK
                     SYFDTIPTDIEEAAMIDGLSRIQIIIRIIIPLAISGIISVFVYCFMVSWNDYLFASIF
                     LSTSEKFTLPIGLNTLFSTPDYIWGRMMAASLVTALPVIIMYALSERFIKGDLVEGGV
                     KG"
     gene            complement(15812..16681)
                     /locus_tag="LLC22_001338"
     CDS             complement(15812..16681)
                     /locus_tag="LLC22_001338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5434623.1"
                     /translation="MNRPRKHSDLKLAMGLLAPSMLLLAVLVLIPMLSNIQISFFDMP
                     LNPNSDAVFIGLSNYLEILSDSEFYRSLGLTVAYTFLVVAGSTALGLAVAILLNRKFR
                     FRKTVRSLILLSYVTPSISLIFAWKYMFNNSYGIVNDLLVDRLQLFNEAPLWFDQPVA
                     SFFMVVLFAIWRYYPYAFISFLAILQTVDKTLYEAAEMDGANAWQKFKIVTLPAIKPV
                     LATVIVLRSIWMFYMFTDVYLLTNKVNILGVYLYQTAFAFNDLGKAAAISILLFIIIA
                     AVVLLSRKKVDLK"
     gene            complement(16751..18034)
                     /locus_tag="LLC22_001339"
     CDS             complement(16751..18034)
                     /locus_tag="LLC22_001339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter substrate-binding protein"
                     /protein_id="HBK5434624.1"
                     /translation="MKKIIVTTCLLATGFLLTACGESQSSNESQQTTIQFMHSSVEQE
                     RLSVINELVADFEKENPDIKIKQVPVEESAFNTKIVTLARSGKLPEVMEVSQDFAKVM
                     DKDELIDQTAVQNVIEEAGEDNYYDGAKNLVRSEDGKSYIAAPISGWVQGIWYDKEKL
                     SEAGFSEPENWDDILKIAQHFTDKENKQYGIAMPTAEGTMSEQAFSQFALSNGANVLD
                     DEGEVTIDTEKMREALSFYQNLSQYTMPGSNDVTEIKDAFMNGTAPMAIYSTYILPSV
                     YEAGNSENIGFAIPTQKDQAVYGTVSGLTISSGLDEKQKEAAEAFTAFLSQPKNMEKW
                     VLMSPGGAQPVNKQVVELDGYKENEVIKSFGELPSEIASAFDEVQVFGLVGEKNFTKM
                     GDITSSGVIGKAVNQVTVGNEDVDQALADAQKNTK"
     gene            complement(18048..19733)
                     /locus_tag="LLC22_001340"
     CDS             complement(18048..19733)
                     /locus_tag="LLC22_001340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphorylase"
                     /protein_id="HBK5434625.1"
                     /translation="MYTKLLQAIYRDSDLSEKTASMIEQKVSVYQQKKGQAGKLHWDE
                     EDIFLITYGDQFFEEQQPTLRTFKKFYQKYLADTFRVVHFLPFFPYTSDDGFSVVNYQ
                     AINDRLGTWEDIEEMRSETRLMFDFVCNHMSAESTWFQEYLNLNDTYKDFFIDLPLDT
                     DTSSVTRPRTSPLLTTFIDKNGKEKHVWTTFSEDQVDLNFKNPEVLLKMIDILLFYLE
                     KGASFIRLDAVGFLWKELGTSCIHLPETHKIIQLFRAIADEAAPGTVLITETNVPHKD
                     NISYFGNGENEAQMVYQFSLPPLTLQAIRSGNTSKLKEWLKTIDFASKKTTFFNFLAS
                     HDGIGLNPVRGILPEKTILELVEQLKKEGARVNYKKNPDGTTSPYEINATYLDALSSP
                     TDTTEWRSKRFLAAHSFLVTLPGVPAIYIQSVLGSRNDYKGVEKTGENRKINRQKFLL
                     ADIEKELQTDPLRTAVYGELTQMLSIRKKEKAFHPNSLIYLLDSADSFISFIREAKEE
                     KVLVIHNFSNQSAGYLLPKGDYLDLFSGQIIHCSQERKLIFQPYEYMWLKIIK"
     gene            20008..21033
                     /locus_tag="LLC22_001341"
     CDS             20008..21033
                     /locus_tag="LLC22_001341"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434626.1"
                     /translation="MKPTIYDIAKKANVSKSTVSRVLNNQPNISDKAKASVLQAIKEL
                     NYEPSKIARGLSGNGFDAILALSHRTSHTTYGNPFFSDVIQSISAVSEQNNFDLILQT
                     AKTPEEELEKCAKKIQEKMIRGIIILSSTMDETLLFELDQYNIPIVVIGKVGNDYTNI
                     YSVDTDNFQDSYDLVETLIKNGHRHIGCLHAPTEVYVSNDRLNGYRQCLFDHHLDIRN
                     EWIIDGGFRLEDSMAAMNDLMKLRERPTAIFSTDALKSLSIYKVAEQSGKQIPDDLSI
                     AGFSDPLLSSLFSPQLTRIDIPTNQLGIKATELLFQLIHHQYPEEKRIILSTEITLTD
                     SIQQQEM"
     gene            complement(21628..25302)
                     /gene="rpoC"
                     /locus_tag="LLC22_001342"
     CDS             complement(21628..25302)
                     /gene="rpoC"
                     /locus_tag="LLC22_001342"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta'"
                     /protein_id="HBK5434627.1"
                     /translation="MKWREPLLIDVNKFESMQIGLASPEKIRSWSYGEVKKPETINYR
                     TLKPEREGLFCERIFGPTKDWECACGKYKRIRYKGIVCDRCGVEVTRSKVRRERMGHI
                     ELAAPVSHIWYFKGIPSRMGLVLDMSPRALEEIIYFASYVVIEPGNTNLEKKQLLTER
                     EYREKREQYGQEFQAAMGAEAIKQLLDNVDLDAEAAELKEELKSAQGQKRTRAIRRLD
                     ILEAFRASGNQPSWMVMDVIPVIPPDLRPMVQLEGGRFATSDLNDLYRRVINRNNRLK
                     RLLDLNAPGIIVQNEKRMLQEAVDALIDNGRRGRPVTGPGNRPLKSLSHMLKGKQGRF
                     RQNLLGKRVDYSGRSVIVVGPFLKMYQCGLPKEMAIELFKPFVMRELVQRELASNIKN
                     AKRKIERQEDEVWDVLEDVIKEHPVLLNRAPTLHRLGIQAFEPVLVQGRAIRLHPLVC
                     EAYNADFDGDQMAVHVPLNEEAQAEARMLMLAAQNILNPKDGKPVVTPSQDMVLGNYY
                     LTMEEEGREGEGMVFRDQNEAVIAWRNGYVHLHSRIGVNPNSLGEKPFTEWQKERTMI
                     TTVGKIIFNEIMPPEFPYLNEPTDFNLTVQTPDKYFVEAGTDIPAHIKEQELVLPFKK
                     KNLGNIIAEVFKRFKVTETSKMLDRMKDLGYKHSTHAGITVGIADISVLNEKQEIIEN
                     AHKQVETITKQFRRGLITDDERYERVIAVWNAAKDSIQQKLMEGLEAKNPIFMMSDSG
                     ARGNISNFTQLAGMRGLMAAPNGRIMELPIISNFREGLSVLEMFISTHGARKGMTDTA
                     LKTADSGYLTRRLVDVAQDVIIREEDCGTDRGLEIQAIREGNEIIESLEDRLVGRYTR
                     KEVRHPETNELIIAGNQLISEDIAKQIVDAGVETVTIRSVFTCNTKHGVCKHCYGRNL
                     ATGSDVEVGEAVGTIAAQSIGEPGTQLTMRTFHTGGVAGDDITQGLPRVQEIFEARNP
                     KGQAVITEVTGDVIDISEDPATRTKEVTIKGKTDTRTYTVPYTARMKVAEGDMIHRGA
                     PLTEGSIDPKQLLQVRDVLSVENYLLREVQRVYRMQGVEIGDKHIEVMVRQMLRKVRV
                     MDPGDTDILPGTLLDIADFKDQNYNTLVSGGVPATSRPVLLGITKASLETNSFLSAAS
                     FQETTRVLTDAAIRGKKDPLLGLKENVIIGKIIPAGTGMQRYRDMEPKEVGVASENVY
                     SISDIEAQMAAEDAMNNQTK"
     gene            complement(25360..28977)
                     /gene="rpoB"
                     /locus_tag="LLC22_001343"
     CDS             complement(25360..28977)
                     /gene="rpoB"
                     /locus_tag="LLC22_001343"
                     /EC_number="2.7.7.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBK5434628.1"
                     /translation="MAGHVVKYGKHRERRSFARISEVLELPNLIEIQTDSYQWFLDEG
                     LREMFEDILPIDDFNGNLSLEFVDYELKEPKYTVAEARAHDANYSAPLHVTLRLTNRE
                     TGEIKAQEVFFGDFPLMTEQGTFIINGAERVIVSQLVRSPGVYFHGKVDKNGKEGFGS
                     TVIPNRGAWLEMETDAKDISYVRIDRTRKIPLTVLVRALGFGSDDTIFEIFGDSETLR
                     NTVEKDLHKNASDSRTEEGLKDVYERLRPGEPKTADSSRNLLNARFFDPKRYDLANVG
                     RYKVNKKLDLKTRLLNLTLAETLVDPETGEIIVEKGTVLTHQVMETLAPFIDNGLNSV
                     TYYPSEDGVVTDPMTVQVIKVFSPRDPEREVNVIGNGYPEAAVKTVRPADIIASMSYF
                     LNLMEGIGNVDDIDHLGNRRIRSVGELLQNQFRIGLARMERVVRERMSIQDTETLTPQ
                     QLINIRPVVASIKEFFGSSQLSQFMDQTNPLGELTHKRRLSALGPGGLTRDRAGYEVR
                     DVHYSHYGRMCPIETPEGPNIGLINSLSSYAKVNKFGFIETPYRRVDRETGRVTDQID
                     YLTADIEDHYIVAQANSPLNEDGTFAQDVVMARAQSENLEVSIDKVDYMDVSPKQVVA
                     VATACIPFLENDDSNRALMGANMQRQAVPLINPQAPWVGTGMEYKSAHDSGAALLCKH
                     DGVVEYVDASEIRVRRDNGALDKYDVTKFRRSNSGTSYNQRPIVHLGEKVEKGDTLAD
                     GPSMEQGEMALGQNVLVGFMTWEGYNYEDAIIMSRRLVKDDVYTSIHIEEYESEARDT
                     KLGPEEITREIPNVGEDALKDLDEMGIIRIGAEVQDGDLLVGKVTPKGVTELSAEERL
                     LHAIFGEKAREVRDTSLRVPHGGGGIVHDVKIFTREAGDELSPGVNMLVRVYIVQKRK
                     IHEGDKMAGRHGNKGVVSRIMPEEDMPFLPDGTPIDIMLNPLGVPSRMNIGQVLELHL
                     GMAARQLGIHVATPVFDGASDEDVWETVREAGMASDAKTVLYDGRTGEPFDGRVSVGV
                     MYMIKLAHMVDDKLHARSIGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGAAYTL
                     QEILTYKSDDVVGRVKTYEAIVKGEPIPKPGVPESFRVLVKELQSLGLDMRVLDIEET
                     EIELRDMDDEDDDLITVDALTKFAEQQTAKELEKKAAEQVEDEKDDVIQNFETAEDNL
                     D"
     gene            29705..30673
                     /locus_tag="LLC22_001344"
     CDS             29705..30673
                     /locus_tag="LLC22_001344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5434629.1"
                     /translation="MKKNIIIGLGAALLLALGGCAQKDNSAEASDGQKTIGVLQLVQH
                     NSLDAAYKGFKEGLAEEGYKEGDNLTIDYQNAQNNQDNLKSMSEKLVKEDPDLLLGIA
                     TPAAQSLLNETTTIPMTVTAVTDLEQAHLVTSNEKPGGNVTGTTDMVPIEKQIGLLLN
                     IVPDAKTIGIMYNNGEANSKIQADLAEKELKKAGVKVKVLTANSTNDVQQVTKSLAKD
                     VDGIYIPTDNTFASAASVVGEVAKETKTPVVAGAVDQVKDGGLATVGIDYESLGKQTG
                     IMAAKILDGKNPSELPVETANDLELYVNKDMAKALGINPDSIKEAE"
     gene            30691..31596
                     /locus_tag="LLC22_001345"
     CDS             30691..31596
                     /locus_tag="LLC22_001345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434630.1"
                     /translation="MTNLLSLFLSSASQGVLWALLAIGVYVTFRILDIADLTAEGSFP
                     LGAGIAAVSITNGYHPLTACLLGFLGGAAAGLVSGLLHTKLKIPALLAGIITMTGLYS
                     VTSRVMGAPNISLLGQPTIFHWVESFGITKDNAVLIVGLLFALIVVCLLVLFLRTETG
                     LAIRATGDNLAMSEANGINTDNMKIIGYMISNGCIALSGSLLAQNNGFADLNSGIGTI
                     VIGLASIIIAEVLLRNQPLFLRLLTVVLGAVIYRFILALVFELNVEPSDSKLASAFVL
                     VICLSFPQIQQKFHLPQKKKGGSVK"
     gene            31593..32399
                     /locus_tag="LLC22_001346"
     CDS             31593..32399
                     /locus_tag="LLC22_001346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348469.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5434631.1"
                     /translation="MNDVLTLENLHHTFEKGTINENHVLKGINLSLDPGDFVTIIGGN
                     GAGKSTLLNSIAGTFSVDQGQILLNGKNITKKSVVERSKSISRVFQDPKLGTAVRLTV
                     EENLALAMKRGKKRGFFRGVKPQDRTFFKDQLVRLNLGLENRLSSEIGLLSGGQRQAI
                     TLLMATLQRPELILLDEHTAALDPATSKTVMELTEKLITEQNLTAFMVTHDMEDAIRY
                     GSRLIMLHQGRIVVDIQQEEKQQLTVPQLLALFKQNSGTALKDDQVLLSS"
     gene            32535..33524
                     /locus_tag="LLC22_001347"
     CDS             32535..33524
                     /locus_tag="LLC22_001347"
                     /EC_number="6.3.4.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin--[acetyl-CoA-carboxylase] ligase"
                     /protein_id="HBK5434632.1"
                     /translation="MGKELDAMTTKDKVLQLLKKTPDFLSGEKLAQQLEVSRTSIWKA
                     IKELEKAGYRFEHGPTGYRYLPSDVLDAKEIQQELRSFIPDLKVQTMLTSESTMKDAK
                     LAAAQGDSVSKLFVADTQEQARGRFGRPFFAEPGRGIYMSLLLHPDKRFDELPQYTII
                     AASACVKAIESVTGRSASIKWVNDIYMDGKKVCGILSEAVSDMESGRISHIIIGIGLN
                     FSVPQNHFPADLQEKAISVFPDGQASVTRNQLISKIWQELFTYLSHPEKALDFYKEKS
                     FVLGKTVSFNQKGTTYVGLAKEIGDHGELIVQTNEQKMSLSSGEISLTSIRTQ"
     gene            complement(33841..34365)
                     /locus_tag="LLC22_001348"
     CDS             complement(33841..34365)
                     /locus_tag="LLC22_001348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289384.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF664 domain-containing protein"
                     /protein_id="HBK5434633.1"
                     /translation="MDYLDMLCESVDRAYDRFERLFEGVSIEEANRFPVEDRAPQIKS
                     MTWLAWHTARELDFQIADLAGTSPIWHSQDWESRFPMTIADNEQDWKHSLEQAKQIQA
                     NQIEDLLGYLRGAADFAISYLRRLEPSELDEVIDENWTPPVTRGMRLVSIIDDAAMHS
                     GQVIYARRLLGLRD"
     gene            34652..>35796
                     /gene="scm"
                     /locus_tag="LLC22_001349"
     CDS             34652..>35796
                     /gene="scm"
                     /locus_tag="LLC22_001349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBK5434634.1"
                     /translation="MKKRASLLVLVALLFNIFSYGVAVSAETYIPKDPGNIYNDLTGN
                     YGLLGIASQFHVFAKNKTTVNAHTDGNIATHELDAKNNFGTELHEGLLNQEINYIQKT
                     DSFANSSGIPTGSTRMNKFVVGSNVDVALQDGHPTVNGSRLDHLTPDDFYKDRAGHEY
                     IDFEQEFAKLNVAANDLATITPAKTYTAADFPDMNNRTIDLTDLSDTGFLLVNIDAEV
                     LTMNTPLQIINPNDQVVVFNVINSSSALNVQSPIKYNDRSNHETEDFSDANISWNFGN
                     EMTDLTISAPFQGTILAPNATIRITQNQDGTIIGTNVILDAATNRWDPNEIFISDNGT
                     DTTDTSDSTDTSTTSDSSDSSTSSDSTDTTSTTSDSTDTSASSDSTDT"
BASE COUNT        10299 a         7561 c         6626 g        11310 t
ORIGIN      
        1 aaatatagta tctccatagg ctttttttaa attctcttca ttaaatacag attctacact
       61 tccgtgagca attagatttc gattcaaaag aataatatta tcaaaatact tctttacctt
      121 gcttaaatca tgatgcacaa ttagcactgt ttttccctga tgtttcaatt cttttaacgt
      181 atccataatt attcgttcac taactaagtc tatccctaca aatggttcat ctaaaaatat
      241 gaaatccgca ttttgagcaa gacatcttgc taaaagtaca cgttgaaatt gtcctccaga
      301 taattctcct atttgatgat tagaatattt tcccatatcg accttttcca aagcctttga
      361 aactctttgc cattctgcat ttttaattct ttgaaaaact ttcattccgg catatgttcc
      421 catagataca cattctttta cttttattgg aaaagtaaaa tcaatatcag ctttttgctc
      481 tacatatgca atcttcacca gttttttatt gatatcttca ttattaatgg agacctctcc
      541 ctgatgaggg ataatattta acattgcttt aagcaatgta gattttccag caccatttgg
      601 accaataata cctgttaaag caccttcttg tatttttaaa gaaatctcgt tcaatgctaa
      661 aaaatcgtta taacaaacat taagcttttt cacttctaac ataactttct ccttctaaat
      721 gataatgatt atcacgatca tatggtatac aaaaattata ttttagtcaa ccctaaattt
      781 tataatttag atttttttct gttgctgaag attagaatga caaaactatt tgaaactacg
      841 cgtatagtaa gtagctttca aaatatataa aaaaggagcg ttctcaaatg agaacatgct
      901 cctaaaacta ctttattggc gtatggaaaa attatactta aagtggatag cgggttgaat
      961 aagttgataa gcatcaaaac atttataaaa attattcaag actatgtctg ttccatatac
     1021 aaatatgaaa atcagtaaac tccatttaac ttttttcgta gtgtgtcttt ttatacatgt
     1081 ttatcgttat taatagtgaa taggaaaaaa cctatttttg atcattgaca attaaataca
     1141 atttttgaat aacgatccct gctattcgag ctagaaactc aagtacgcca tgacctgatt
     1201 agcgacaaat acttagagat ttctttttgt tctgggaaaa caaaatgcca tgacaatagc
     1261 agcaaataat gatacttccg taaggctcgc cgtaaactgg ggagaggtga aattcctatg
     1321 tgcttaccca aagcaattca aaaattctaa tcttttttag gagatgattt tataaaattg
     1381 agagtctact tgaataaaaa acaaacctgt gagtttctag gaattgataa taatacttta
     1441 gataagtgga ttcgtatata taattttcca gtaatcagaa ttgacggtat agttcgcttt
     1501 gacatagagg atatcaaaga ttttatgaat acatttaaaa caatttgaaa atttcttctc
     1561 gccgcatata ctaagaatag cgaaatatac tgccttactt tttaagggag tgaggaattt
     1621 tgcctacaaa actttcaaat gggaaatata aaactaatct gaggtatcca aaaaaattca
     1681 gagaaatcac tggaattaca tcagaaaagt atcaaaaagt atttccaact aggcaattgg
     1741 ctattaaagc cgaaaatgca atgaaaagga aaattgaaac agttttaaga gaggagaatg
     1801 caaattcact agaattaaaa ggaaaaataa aatttaagga attctatgaa tcaaaatggc
     1861 ttcctagata tgaactaggt cagactacta gatcaaaaag agctccaagt tacgtaacaa
     1921 ttagtaatac taaagatata ttccgattgc acatccttcc aatgtttggt gagtatgcaa
     1981 tgaactatct aaattcaaat actgagataa tatcagatga attaacaaaa aaatcgaaag
     2041 aatacgcaaa tataaaaatt atcaaaggat atgtccgttc tatgtttgat attgcagaaa
     2101 tactaaatta tattgaattt aaccgaacta ccaaaattat tcaatgtatc actgcaccta
     2161 aaaaaattgc tttagaagaa agaaggatac gggaaggtaa tcaagcatta tcgtcagaag
     2221 agcttattgc ttggatagaa gcagtaaaca ctgacttgaa taatcacttg cttactcttc
     2281 atgactatac tcttttcatg cttaccctat atcttggtga tagaaaaagt gagacgtatg
     2341 ctttgcaatg gaaatatatc gactttgaga aacaaacggt tcgccttaaa catgctttgg
     2401 ataaatatca aaaaaagaaa tttacaaaag gtcgaaagga taccgtaatt caagtacccg
     2461 aaattgtaat ggcattacta agcaaatgga aatcagtgca agctgagcaa ttgttgagat
     2521 taaaaattaa tcaaacacca gatcagtatc tctttaccta tactaaacca tccggagaag
     2581 taaattgccc tgttcacgct gattacctaa actatcgaat caattcaatt aaaagacgac
     2641 atcctgaatt ggctcattta tctccacata agcttcgtca tacctatgca actatagcta
     2701 gacaaggcgg agcaaatatg aatcaaatat ctagtgcttt aacacactca gatatttcta
     2761 caacgagaat atacgtaaat acaccagatg tagtagataa aactgttttt gaagcctttc
     2821 agagaggatt gaataaatgt gattagtatg tgttcttaaa tgtgttctta aacaagaaaa
     2881 agacactttt caaacaattg aaaagtgcct tgaaacattg atatataaat aatattaacg
     2941 tttagagaat tgagatgctt tacgagcctt tttgagacct ggttttttac gttcgaccat
     3001 acgtgcgtca cgagtaagta agccagcacg tttaagagct aaacggaagt caggatcaac
     3061 ttctagcaat gcacgagcga taccatgacg gatagctcct gattgtccag cgtatcctcc
     3121 gccgtttacg ttaacaaata cgtcatatgc gccttttgtt tcagtaacag cgaaaggttg
     3181 attgattact tcacgcaagt cagcatgtgg aatgtattct tcaacatctt ttttatttac
     3241 agtaattttg ccagttcctg gtactagacg tacgcgagca actgcgtttt tacgacggcc
     3301 tgtgccgata tattgaactt gtgccaatga aattccctcc tattagatta agtttgtgat
     3361 gtctaaaact tctggttgtt gtgctgcatg tggatgttct gctccaccgt atacgttcaa
     3421 ttttgtaaat tgtttgcggc ctaaagtgtt tttaggaagc atacctttta cagaagtttc
     3481 gatcaaacga cgagaatttt tagcacgcaa ttcgccagca gtgattgatt tcaatcctcc
     3541 tgggtagttg ctgtgacggt aataaatttt gtcagtcgct tttttacctg ttaatttcac
     3601 tttgtctgca ttgatgacga tgacgaaatc accagtatcc aaatgaggtg tgaaagttgg
     3661 tttattttta ccacgtagta cagatgcaac aactgttgaa agacgtccca atggaacatc
     3721 agttgcgtct actacatacc atttacgttc tacttcgcct ggtttggcca tatatgttgt
     3781 acgcacgtta ttttcctcca atttaagttc tgatgtttga catacacttc gagtttccgg
     3841 ggctctttgt ggggcaaaca ataccattta acatattacc cgctaatcta gtcaatgtca
     3901 acgtttttct gcttgattga aaaatttata tgaaacttta cttcttttct ttcttttata
     3961 taaaagggtc gtttcctgtc aaaatgaaaa acaaaaagag gctgtgacaa aagtcttgtc
     4021 acaacccctt attttgaata aacggtgttc tcctgccaac tcctcggtca caagtcacaa
     4081 tatccataaa acataagaag ctgtttttta aaattgtttc ttgtgactcg gagctgaacg
     4141 gcaggcttac aacctcttgg taaacggtgt tcaatcagct gaccctcggt attagctcaa
     4201 aaaacggcaa aatatgagga actattttga cgtttgtttc tctaatactc aggtcaaaac
     4261 gctgatttca caacctcttt ttcggtcaag ttcaacaaca gtttttacgc gtcgatctct
     4321 ggcgctttgc ccaaatgagc ttggatcatc cagatacgtt tttctgtggc tgttttgaat
     4381 tcgataaaga tatcttgtgt tggatcgtcg ccttcttctc cagaaacttc gattcctttt
     4441 tggtaaagat ctgctagata acgatagcct gcaacaagtg tttccaaacg ttctggaata
     4501 gtacgatccc agcggccaat ttcatcaggg atttttgtgt tatctgcaaa ttcacgcaat
     4561 gtagaataag gtgaaccgtc taatgtgatc aagcgttcgg atacttcatc taactgagcg
     4621 ttcaaatcat ccatgaactc atccatcatt gggtgcaatg taaggaaacc tggtcctctc
     4681 atgtaccaat gtgtttggtg aacaacaaca gacatttggc ttagatctgc aactaattga
     4741 tttaatactt ctttggtttg ttggaatttc atctttcttg cctcctaaca ttttcttaca
     4801 cttaaaataa tagtagactt tcaatgaaaa gtacaacaaa atcatttacc tgagaacgat
     4861 tttcagttcg cttttttatc cgtaaagcca atcatttttc agaatcagct aattcttctc
     4921 gcagttgagc aaattgctga taagtctgtg ctaaatgctt ttgtgtcgaa acaaataatg
     4981 gatagatttt ctgatatttt ttatgatcag tttcttgtac tccaacttgc tctttcaatt
     5041 ctatcaattc ctgtgcttca ctgatacttt ggatctttcc gatgcttctc cagcctaaaa
     5101 tcacagctcc taatgcggat gcttctgtga cagtagggaa aacaagcggg taacccagta
     5161 catcagccat catctgacga aaaatcggag attgagcaaa cccgcctgta gcacggatct
     5221 ctgtgagctg attttcctgg caaactcctt ttaaaatccg ataaaggttg agacagatcc
     5281 cttctagaat cgccttcatc atttcttttt ctgtatgttg ccgctgtaaa ccgataaaac
     5341 tgccaaacgc atctgcgtcc caaagcggtg ctcgctcacc aagtaaatag ggatgaaaaa
     5401 tcagaccatt ggcacccgct ggcacaaaag cgatagccga aagcagtgca tcatatggat
     5461 tttctccttt ttctttagca gattgaacga cttcctgtaa aaatgtatgc cctgcccaat
     5521 caaagatgcc agcaccattg ctagtcgctc ctcccactac ccaatgtttc tgatccagaa
     5581 cataacaaaa cgtctccatt tctggatgga actgaggctg agtagtaata aaacgaagtg
     5641 ctccgctcgt tcctacggtc aaagcggcga tcgtatcacc aaaagcacct aaccctagat
     5701 tagaaagcgg cccgtctgcc cctcccaaaa caaatgatat atcatttggc aaacctagtt
     5761 ctgctgctgt ttttgatggt agacctgtta cttgataggt ggaaggaaag acttgcggca
     5821 attgctctat tcgaatgttc aagtagtcaa gcacttcttc tgcccattgg aattcatgga
     5881 tatcaaaata tccagttcct gaagctgttc cgtagtcgct gatcagttcg ccaaacaatc
     5941 tataaaagat atagtctttg ataccgacaa aataagcagt ttttttgaat aattcaggtt
     6001 ggctgttttg cagccacttg attttgttca atggtgtcat tggatgaatc ggcgtcccag
     6061 tctgccgata aaattctttg ccaagcacgg tatatttcag tttttctgct tcgtccgctg
     6121 ctcggttatc tgcccaagtg atcattcgag ataacggtgt tttctcttca tccaacaata
     6181 tcaggccatg catcgcagag gagaaggaga caaattgaat gattgtgtct gaaggcaact
     6241 gtttaattac ttcttttata acggtgcaga caccttgaaa gatcaattcc tgatcttgtt
     6301 ctgccatccc ttgtgtttct tggatcaaag ggtagcgaaa ataagcggat gctgcttctt
     6361 gggcttcatc tgtgaaagca actgctttgg tttgtgtggt tccgatatct aatccgattg
     6421 aaacgttcat tttttcacct caaattttat gtatgtacaa aaatttagtt taagcttgcg
     6481 tatcttggtt ttgaaaaggg ggagatggcg tgttacttta ttttatcatt ggttgctgta
     6541 tcggatcatt tttatgttta accgcccagc ggattccgtt aggtcactct attatttatc
     6601 ctagatctca ttgtgtcaaa tgctgtcgtt cgctttcttg gtatgaattg attccgattc
     6661 tctcgatcat cgtccaacga tttcgctgcc gctattgcag gtgtcggttg cccttctact
     6721 atttgttggc agaagcctta tgtggtggtc tttttgcctg gttctttact ttttcttccg
     6781 caagaaattt ttcgacgttc atatggatgc tttcggcttt gctattttcg ttgatggatt
     6841 tattttactt catggtccat tctcacacgc tattctgttc ttgggcaatt ttatggattt
     6901 tttggttgca ggccggcgtc ttccaatggc aaagtgtgct gttaacgttt atcgtaggcg
     6961 gtgtgtgcct tcgctatggt caatcctatc tcggagctgg cgatactctg ttgatgcttt
     7021 cttggagtgg tggcttgtct ctagaagagt tgcttcagat cttgtttctt gctagtctgt
     7081 ttggaatatc cgttttttct gtttacttta tctgtcataa aaaaaagttg gaaaagctgc
     7141 ctttcattcc ttttttgagc agtgcgttgc tgattgtcct tcatcttagg tattgaaaaa
     7201 aggttgtgac aaacgacttg tcacaacctc tgatatatag tgttctctta ccaaatcctt
     7261 gtgacttgga gctaggcgac aggttcacaa cctctccact aaatggtgtt caatcagctg
     7321 accctcagta ttagctcaaa atgctggttt tacaacctct gatatacggt gttccataag
     7381 tagctttttc ggcttcttat ttcttgacgc cccaatgtcg acgaaggaaa cctgcacgtc
     7441 cagaaccttc tcgataaaga ttgtaatgga gcttgttttt cttgtaataa tcctgatggt
     7501 aatcttctgc aggataaaat tcgcttcttg gttcgatttt tgtcacgatt ggcttatcga
     7561 atcgcccgct gtcttgcaat gcttgttttg aacgctctgc aatatttcgt tcttcttcat
     7621 cattatagta gatcactgga cgataagaat caccgcgatc agcgaactgt cctaatgcgt
     7681 cagtcggatc ggtttgctgc caatagattt ccaccaactg atcataagaa ataacttctg
     7741 gatcatattc gatctctact gcttctgtat gccctgttgt gcctgttgtt acttgttcat
     7801 aagttggatt tggtacatgc ccgccagtat aaccggatgt cacagaaatg atccctggct
     7861 gctcttcaaa tggtttgacc atacaccaaa agcatccgcc tgcgaaaact gctttttttg
     7921 tcatataaaa tccccctttt ttctcatcat accttgattt ccaaaaggag gataacgttt
     7981 tgcttgtgac agaaaaaacg gaaactatta tatacgtgat acggcttctg ataaatgcca
     8041 aaacgaacgt acttgatcaa aaacggttaa atcaggaatc acatattcag cagaaggaag
     8101 atttatgttt tcacctattc ccaatacatg catgttacca gccaaagctg cttgacaacc
     8161 agcttctgaa tcttcaatga ccaagcatgc atttggcggt acattcaatt gctgtgctcc
     8221 tttgagaaaa acttctggat caggttttgc ttttgatact tgcgtgccgt caataaggac
     8281 atcaaaataa cttgtcaaat tcgttttttc taaaatgagg cgtgcatttt tgcttgctga
     8341 tcccaatccg atcttgatgt ttgttttttt caagtactca agaacagcta ttgcaccagg
     8401 caaaacggat gtttcatcca ttttttgaat cgcttgaaga tatagattgt ttttttgctc
     8461 agcaaaggct gatttctctt tttctgagaa tttctgttcc atttttccaa atgacagcaa
     8521 tcgctctagt gactcggttc tggatattcc tttcagttgc tcgttttctt tctcagtgaa
     8581 tggaatggac agctggttag ctaaaaccag ccacgcttcg taatgataac gagctgtgtc
     8641 tacaagaacg ccatctaaat cgaatagtgc tgctttgatt ttcatcgatt acctccttga
     8701 aaatgaacga cttgaagtaa agatgcgatg tttttagctg tgcgatgaag attatcagtg
     8761 gcttgctgta aagcttcttg taaaggcaca gctgcaggaa ggatcggaaa aacggccgaa
     8821 atgccaacat ctgctgcttt ttcgcttcct ttaccaacac ttccgcaaat agctatcaca
     8881 ggaacgccct ctggtactct tctagcaatc ccaactggcg cttttccttt tagactttgt
     8941 ccatctagac gtccttcgcc tacgattacg aggtctgctt gctgtacccg tttatcgaac
     9001 tccagtaaat ccaatacgta gtcgatgcca gagactattt tccctgaagc aaatgctaac
     9061 agtcctgcac ccattccacc accagcacta ctgcccgatg cctcgattac ttgaggggca
     9121 aatctcatat aaaaatcatg catggcttgg tcagccactg ctaattcatt ttctttcaag
     9181 cctttttgtg gtccgaaaac aaaagaagcg ccttcttttc cgcataaaag attagtaaca
     9241 tcagtaatga cagtgatttt ggctttaatc agctcaatag gcacgttcgt tttatcaact
     9301 gtagcaattt tacctagatt ttctcccagt gcttctactt tttgattatc ttgatcgtaa
     9361 aaagcataac ctagaccttc tgccatgccg atgccgccat cgttggtact acttccgcca
     9421 acgccgatga tgatgtgtcg aacaccttgt tgcaacaatt gtcgtatcag ttctcctact
     9481 cctcgcgtgg ataacctaag tggctgttgt tggtttagtg ggacatcttt caatccgacg
     9541 atttctgcca tttcaaaaat cgcagtttga ccgtctgaag cgtactggat ttctttgttt
     9601 ttgccaaatg cattagtaac gactgctgtt tgccgcttca accttaaact gtctgctaat
     9661 gatgaaaccg ttccttctcc tccatcgcct ataggtagca gatcatattc agcctgaaca
     9721 aaaacttctt gaaaacctga ttgaatggct tgtgctgcct ctaaggctgt cagactttct
     9781 ttgaaagaat ctggcgcaat cagaatacgc attattttcc cctccgttcc aagatcagtt
     9841 ctttttccag ctggtattgg tctccattga caaaaatagg taatgtttct ttcgtctctt
     9901 tttttattac tatttgtttt tttgtcaaaa caaatagcaa cctgtgattt ttccaaataa
     9961 aaggaaaaga aattttttcc catgctgaag gaagtcttgg agaaatagaa agagttccat
    10021 tcgttactgt aatacctgaa aaaccaaata taactgctag ccatagtgct cctaatgaag
    10081 cagcatgaat tccgtcatct gatgaatgcg gatctggtcc taaatcaatc aggcacgctt
    10141 cttggaataa atgatacgcc cattccattt cttggatacg gcaagcctct atggcgtgaa
    10201 tcgctttact caacgatgag tcgtggattg ttttgttttc atagtaatgc aaattcttag
    10261 aaacgattgg ttgagaaaaa tactcaggta ataagtataa cagcatgaca agatctgctt
    10321 gcttgctgac ttggagttca tttacttcgc tacgggcata atcaagtaaa atagactggc
    10381 tgccaggacg ttctttgtaa gtggtcaaat caataactgg cttactgaga tacgtgtcat
    10441 cttgcggaat cagctgttct ttgttaggca ctggcaaata taacttatct aaaaaatttt
    10501 gacattcttt caaaaaaagc ggatcgccag cttgatattt aacagctaag gccacattat
    10561 aatgcgccag atagttcgta tatgcattat tgtcgatata ttctgtgtat tcatctggac
    10621 caatgactct gtgtatctct aaatgatcat cgacttttac agctctgctc agccaaaaag
    10681 ctgctgtttc atgaatgagc gtttttccct ttgtttctaa aaacgattga tcctctgttg
    10741 cttggacata ctcttgaacg gcataagcaa ggtctgcact gatatgatgt tctgcggcag
    10801 ctgaagcaac ttcttgtctt gttccggttt tgatattcaa tgcagcaaat ttgggtgtct
    10861 cttcctgacc agtgtgtgcg ctttcccatg ggaaaagtgc accttgatag tgataatctc
    10921 ttgctttttg ccgtgcgcct tctaatcgat cataacggta cagcagcaaa ttctttgcta
    10981 cttcaggaaa ctgatataaa aagaaaggca ggataaaaat ttccgtatcc cagaaaacat
    11041 gccctttata accttcgcca gttagtccct tcgcccctac actaacactt ggatcattgc
    11101 ggggagtcat aatctgtaaa tggtaagcag cgaagtccat cgctaactga tcgaaagaag
    11161 aatcgccttg gatcgttatc cgatgctgat gccaaaaatc tgtccaataa gacatcgact
    11221 gctctaaaat ttctgtataa ctaacgcttt tctgggcttg ggcaatactt ttcttaaacg
    11281 ggtctgtttg ctgaagagag gtagagagca cgatgatctt ctccagcgta aaggacgtat
    11341 tttttctgat cttttctgaa aaggaagcgg tgatccggcg attttttgct tggaatacac
    11401 ctgctttatt gaatttagct gcaatcccaa tatcaatttt actttctgtt gtctggtagg
    11461 atgcactgat caaatcgtca ccaaatactc gcagttcttt ttcaaccaac tgctgtgtac
    11521 caaaattggt ttgctgtcca tcgatacccg ttttcacatc tacttggcag tcttcggtca
    11581 acggcttgat gaccactttc agggctgcct gatggagatt attttgatca gcaacacgac
    11641 aagtaatgac ttccactttt tttccttgag cagtttcaat gagcgcatag cgtttaagct
    11701 ctcccatttc taaatctagt gcccgctcgt atgcaagaac tttcatcgtc tcaagagaaa
    11761 aatgttcacc gtcgattttt atttcccatc tgatgacatc tgggagattc actaactcgg
    11821 ctgattctgc tcctaaaggt cggttatata caccagctgc aaacattccc cttacttgat
    11881 tccgatagtc ttcctcctgg cttcctctga taccaaaaaa tccatttcca atggtcatct
    11941 gactcgcata cttattgata tactctaaat caaactgttt ttcttctact ttcataaggt
    12001 aataacttct cctgtttctg ccgaacgata taaattttcc accagattct ggatgacata
    12061 tccttgccag ccatctgcaa tcatctgagt ctggtcaccg agcgcccgat tcacaaaatg
    12121 agccatactt agttcatgtg ggtcattaac tggcgtggtc ttttgtaagg aaaccagctt
    12181 tccatctaca tcttcgaata gttcgcctgg atacagatta gcacctgcct gatcgccaca
    12241 aaaagccaca ttcagtttgt cttctctgat attcaaagca aacgaagtat tcagttggat
    12301 gatcttgccg ttttctaatt ccagtgtgcc aaaaattgca tcttctactg tgaatttgct
    12361 tggatcccat ttcccgaatt tccctgaatt ttttttcgta ccaatttttt ggaagctgta
    12421 cgcccgaacg ctttttactt taggaaatcc agtaatatac atcgctgtat caagcatgtg
    12481 aatgccataa tcgatcaaag gcccgcctcc ttgaagttct ttgtcgataa acgttcccca
    12541 gcctggaaca ccagaccgac gaagcgcatt cgcttctacg taataaatat ccccgagaac
    12601 atcaagatga ttcttgatca ttgttgcttc gtcagaaaaa cgatgctgga atccataagc
    12661 caaaatctgc ccgtttttat cggctgtctc tgccatcttt cttgcttgat cagctgtcat
    12721 agctggtggt ttctcgcaca tcactgaagc attagcttcg agggcagcca atacatgttc
    12781 gaagtgaaag cgattgggtg tacagacact cacgatatcg ggagaaatct cattcagcat
    12841 ttgtgtaact gatgtatacg catgagaaaa tcctgtacgt cggcaaaagt cttctgctcg
    12901 ctggctgact ggatcaacca cagcggccaa ttctaagaca tctgatcttt tttgataata
    12961 agcagcatgt actttttctg ctacttgtcc agcgcctatg attgctactt tcttcattta
    13021 tttctctctc ctttgcttat ttacttattg ttattctttc tctattcttt ctctaaatca
    13081 tttaaatgac gcgctgtttc cagacagttt ttcaagtatt gcaatgattc ctgataaatt
    13141 ttcacttcat tttctcctcg caaacgacat tcatatacca tataaccttc atactcattt
    13201 tgaagtagcg tttgaaaatg gcgagtaaaa tcaattgcgc cagatcctgg ttggtagcga
    13261 tgattatctg ctaaatggat atgacccaca tactcttttt gcgtagtcaa tgcttttgaa
    13321 atatcatctt cttcaatatt catatgataa aaatcagcga tgatctgcac atgtttcaat
    13381 tgattagagt caatgtaatg acgcgcatcc gctaacaaat tgatcatatg gtcttggtat
    13441 cggttcaaag gctccaaata aataaccgta cctgtttctt cggctacttt atctaaataa
    13501 cgaagtgatt cgctgactgc tttatagtct ccttctttgc ttcggggtga aaccatcggc
    13561 ggtaatcgat aagtgaacat tccccaagct gctgggataa cgattccttt gcctccaacc
    13621 tcgcttagtg cacgcaaaat ctcagcaatt tgacgtacac cattaagacg ccgttcttcg
    13681 ataaagtcac cgatccaccc atcgtagccg ttacaagctg tcactactgg gatccctgtt
    13741 tctttgattg cctgtttgac tgtgtcgata ttttctatta acaacttacc gtcgatttcg
    13801 tattcttcaa atccacagtc tttgataaat ctaaattttt ctaaaatgtc tcttgggaaa
    13861 aatgcttgat cttgcgtacc gaatttcatt gttctcctcc tcggacttga acgcccattt
    13921 tgatactttc ttctgggtgc tggtctacat aacgcatgta agcttctgcg ctttctgcaa
    13981 atggcacaac tggatcaatg atttcttcac aatccaagta accgttcatc aataattccc
    14041 aacatgtgtc ctcgattcgt ttacggttcc atcttgggta atctgggttt ggttcactag
    14101 atgctcgagc aaagacgatt tttgcattat tgaaatgtgc ttcgcgacca agattaaacc
    14161 cagctggaaa aggtttagca aaggcaacat aagaaatgat cccgccatag ccgatccctc
    14221 ttaaagaagc ttgtaatgcg gcagcactgc cactcgtttc aataactgaa tctactccac
    14281 gtttatctgt caattccttt agacgaaaac cgacatctgc tttcatagga tctagcgtgt
    14341 aatcggcacc gtatttttct gctaattctc tacgctgcgc tatgggatcg atcccaacga
    14401 tggtagtagc acctgctttt ttagctaatt gaatcgcaat ttgcccgata gcgcctaaac
    14461 cgaagattgc tacagcatca cctgctcgaa catgtgcttc ccggatacca cctaaagcga
    14521 attgagcagg atcgtaacat actgcatttt tccattgatc caaccgatca agtttacgta
    14581 gtttataatt atcaacaccg tttgtaatca gcgtttcacg aatgggtcca taagtgcaga
    14641 ctaactctcc tttttgatac tctgtcacca aactgcccgt ttcttcgatc gtaccgacaa
    14701 tcatatttcc taattgaaat tcgccaaata ccacaccgcg ttggcttcct tcttctcttg
    14761 gcaagaatag gcgccattct tctgaaaatt cttcatcgat aaatggactt aatcctctaa
    14821 agtcgacaat ttctgttcct ggttttggag tagcgaaaat tactcggata cgtacttcgt
    14881 tcttttcgat ctcacggtct tcgtaatctt tgaatccggc tattcttggt tctaatgcaa
    14941 ctaatttttt catcttttct ttcctctttc ttttcttttt atccttttac gccgccttcg
    15001 actaaatcac ctttaataaa tcgttcagat aacgcataca taatgatgac tggtaaagcg
    15061 gtcaccaatg aagcggccat cattcgtccc caaatgtagt ctggtgtact gaataatgtg
    15121 ttcaaaccga ttggtaaagt aaatttttcg gaggtcgaca ggaaaatcga agcaaataaa
    15181 taatcattcc acgaaaccat aaagcaataa acgaagacag aaatgattcc agaaatagcc
    15241 aatggtataa tgatccgaat aatgatctgg atccggctaa gaccatcgat cattgctgct
    15301 tcttcaatat cagtcggaat cgtgtcaaaa taacttttta gcatgaatat cgcagtagga
    15361 agtgtttgaa cgaccatcgt gataatcagt gctgtattgg tatcatacaa acctagaccg
    15421 gaaatgattt taaataatgg aacaacgatc aaaataccgg aaaacatata aacggtgtaa
    15481 aagctagcat tgattttcga gcgagctttg aagcgtagtt ttgacaaagc gtatgccccg
    15541 ctgatcccaa tcactactgc agttacggag gctatcaagg agatcactaa actatttttg
    15601 aaatacatga tgaatggaaa aatctcagca ttgaaaatat cctgataatg ttcaaaagtc
    15661 cattctttcg gaaaaatagt ttgtgtcgtt gcaattgctt cttgtgaatc cttgaatgat
    15721 gtcatcagca tgatcaaaaa tggaaacaaa ttgacagcta atagcaacaa aatcgtcgcg
    15781 taaaataaga ttttcctgct ctttttattt ttcatttcaa gtccaccttc tttcgtgaga
    15841 gcaagacgac cgctgcaata atgatgaaca atagaatcga tatagctgct gcttttccaa
    15901 gatcattgaa cgcaaaggct gtctgataca aataaacgcc taagatattg actttattcg
    15961 tcagtagata gacatctgta aacatataga acatccagat agatcgtaaa acaatcacag
    16021 ttgctagtac tggtttgatt gccggcagtg tcacgatctt gaacttctgc caagcatttg
    16081 caccgtccat ttcagctgct tcataaagcg ttttgtcgac tgtttgcaaa atagccaaaa
    16141 atgaaataaa cgcatacgga tagtatctcc agatagcaaa caaaacgacc ataaagaagc
    16201 tagcaactgg ctggtcgaac cacagcggtg cttcgttgaa aagctgcaac ctatctacta
    16261 acagatcatt gacgattcca taactattat tgaacatata tttccaagca aaaatcaaag
    16321 aaatagatgg cgtaacataa cttaataaaa tcagtgaacg caccgttttc ctaaatctga
    16381 acttgcggtt aagcaaaata gctacggcta atcctaaagc tgtactgcct gctacaacta
    16441 agaatgtgta agcaactgtt aaacctaaag aacgataaaa ttcactatca cttaaaattt
    16501 caagataatt gcttaatccg ataaaaacgg cgtctgagtt aggattcagc ggcatatcga
    16561 aaaaactgat ctgaatattg gaaagcattg gaatcagcac taaaacagct aataaaagca
    16621 tgcttggtgc taaaagtccc atggctaatt ttaagtcaga atgtttcctt ggacgattca
    16681 ttgaaacctc cccctgataa tctgccaata gctatctact tttttcgaac accattggca
    16741 gaacttcttg ttatttcgta tttttttgtg cgtcagctaa agcttgatcg acatcttcgt
    16801 ttccgacagt tacttggttc actgcttttc cgatcacacc tgagcttgtg atatctccca
    16861 ttttcgtgaa attcttttcc ccgactagtc caaagacttg tacttcatca aaagcactag
    16921 caatctcaga tggcagctcg ccaaaagact tgatgacttc attttctttg taaccatcca
    16981 gttcgactac ttgtttattc actggttgag caccaccagg agacatcaag acccactttt
    17041 ccatgttttt cggttgagat aagaaagctg tgaatgcttc agcagcctct ttttgtttct
    17101 cgtctagacc agaagaaatc gtcaatccag atactgtgcc atagacagct tgatcttttt
    17161 gtgttgggat agcaaaaccg atattttctg agttccccgc ttcataaaca gaaggcaaaa
    17221 tgtaagttga atagattgcc attggtgctg ttccattcat gaaagcatct ttgatttctg
    17281 tcacatcatt agagcctggc atcgtgtatt gggataagtt ttgataaaac gacaatgctt
    17341 ctctcatctt ttccgtatcg atcgttacct cgccttcatc atccaaaaca tttgctccat
    17401 ttgacaaagc aaattgagag aacgcttgct cactcattgt tccttcagca gtaggcatag
    17461 caattccata ttgtttattc tctttatctg tgaaatgttg agcaattttt aaaatatcat
    17521 cccaattttc tggttctgaa aaaccagctt ctgataattt ttctttgtca taccaaatac
    17581 cttgaaccca gccgctaatt ggtgcagcaa tatagctttt tccatcttct gaacgaacaa
    17641 ggtttttggc tccgtcataa taattatctt ctccagcttc ctcgataacg ttttggactg
    17701 ccgtctgatc aatcagttca tctttatcca tcactttagc aaaatcctga ctgacttcca
    17761 ttacttctgg taatttaccg gaacgagcta acgtaacgat ttttgtattg aacgctgatt
    17821 cttctaccgg cacttgcttg attttgatgt ctggattttc tttttcaaaa tcagcaacca
    17881 gttcattgat cacacttaat cgttcctgtt cgacagaaga gtgcatgaat tgaatcgttg
    17941 tctgttgtga ttcgttagag ctttgacttt caccacaagc agtaagaaga aatccagtag
    18001 ctagcagaca ggtagtaaca ataatttttt tcattttttt ccacctctta ttttattatt
    18061 ttcagccaca tatattcata cggctggaat atcaactttc gttcttgact gcaatggata
    18121 atttgtccag aaaacaggtc taggtaatct ccttttggta aaagataacc tgctgattga
    18181 ttggaaaaat tatggataac taagactttc tcttccttcg cttcgcgaat aaaactgata
    18241 aaagaatctg ctgagtccag taagtaaatc aaactattcg gatggaaggc tttttctttt
    18301 tttcgaatag atagcatctg ggtcaattca ccatatactg ctgttcttaa tggatctgtc
    18361 tgcaactctt tctcaatatc tgctaacaaa aatttttgcc gattgatttt tcgattctct
    18421 cctgtttttt ctacgccttt gtaatcattt cgacttccca gcacactttg aatataaatt
    18481 gccggcacgc ctggtaacgt taccaaaaat gaatgagcag ctaaaaagcg tttgcttctc
    18541 cattccgtcg tatctgttgg agaacttaac gcatctagat acgtagcgtt tatctcatat
    18601 ggactggtcg ttccatctgg gtttttcttg tagtttactc gggcaccctc tttcttcagc
    18661 tgttccacta attcaaggat cgttttttcc ggcagaatac ctcgtaccgg attcaatccg
    18721 ataccgtcat gggaggctaa aaaattaaaa aaagttgttt ttttcgatgc gaaatcgatg
    18781 gtttttaacc attctttcaa cttacttgta ttacccgaac gaatcgcttg aagggtcaaa
    18841 ggtggtagcg aaaactgata gaccatctgt gcttcattct cgccattccc aaaataactg
    18901 atattatctt tgtgtggcac atttgtctca gtgatcaata ccgttcctgg agctgcttca
    18961 tcagcgattg cacggaataa ttggatgatt ttatgcgttt ctggcaggtg tatacaagaa
    19021 gttcctagtt ctttccataa aaatcccaca gcgtccaagc gaataaatga agcgcctttt
    19081 tctaagtaaa acaaaagaat atcgatcatt ttcaataaaa cttctggatt tttaaaattc
    19141 aagtctactt gatcttcgct aaaagtcgtc catacgtgtt tttctttccc gtttttgtca
    19201 atgaacgttg taagtaacgg gctggtcctt ggtctagtca cgctgcttgt atctgtatcc
    19261 agtggcaaat caataaaaaa atctttgtac gtatcattca agtttaaata ttcctgaaac
    19321 caagtacttt cggcagacat atgattgcag acaaagtcga acattaaccg tgtttcgctt
    19381 ctcatttctt ctatatcttc ccatgtgccc aaacggtcgt tgattgcctg ataatttaca
    19441 acggagaaac catcatcaga tgtatatggg aaaaatggca agaaatgtac aactctaaat
    19501 gtatctgcca aatacttttg ataaaatttc ttaaatgtac gcaaagttgg ttgctgctct
    19561 tcaaaaaatt gatccccata agtaatcaag aaaatatctt cttcgtccca atgcagtttg
    19621 cctgcctggc ctttcttctg ctgataaaca ctgacttttt gttcaatcat agaggcggtt
    19681 ttctcagaca aatctgagtc gcgataaatc gcttgtaaaa gttttgtata catcggattc
    19741 ccctttcttt tttgggagcg ttcccaacga tttgatcata ttatggaaaa cgcttactgt
    19801 caatagcatt tttttaaata attttgatat acacaaaaat acaaataaga aagcttatgt
    19861 atcaataatt aatagcttct taaaaaaata tggtctctca tgatcatgca agctattcct
    19921 aaattttcaa aatcatagac aaaaaagaat gtctattgta ctatggaatt attctaaaac
    19981 gctcccaaaa aggaggtgca tataaaattg aaacctacta tttatgacat tgcgaaaaaa
    20041 gctaatgtct caaaatcaac tgtctccaga gtattaaata accagccaaa tatctctgat
    20101 aaagcaaaag caagtgtact tcaagcaatc aaagaattga attatgaacc gagcaaaatt
    20161 gcaagaggac tgtcaggaaa tggttttgac gcgattctag cattatctca tcgtacttct
    20221 catacgacct atggcaatcc ttttttttca gatgttattc aatccatttc tgccgtttct
    20281 gaacaaaata acttcgactt gattctacaa acggcaaaaa caccagaaga agagctagaa
    20341 aaatgcgcga aaaagatcca agaaaaaatg atccgaggaa ttattatttt aagctctacg
    20401 atggatgaaa cacttctttt tgaattggat caatacaata ttcctattgt ggtaatcgga
    20461 aaagtcggaa acgactacac gaacatctac tcagtggaca cggataattt ccaggatagt
    20521 tacgatttgg tggaaacact gatcaagaat ggacaccgtc atatcggctg tctccatgct
    20581 ccgacagaag tttatgtatc caatgatcgt ctcaatggtt accgtcaatg cttatttgat
    20641 caccacctag atatccgtaa tgaatggatt atagacggcg gctttcgctt agaagatagc
    20701 atggcagcaa tgaatgattt aatgaagcta cgagaaagac caactgcgat tttttctacc
    20761 gatgcattaa aatcattgag tatttacaaa gtggcagaac aatctggaaa gcagatacct
    20821 gatgatcttt cgatcgcagg attcagtgat cccttattgt cctccctatt ttcgccacag
    20881 ttgactcgga tagacattcc gacaaatcag ttaggaatca aagccacaga acttttattc
    20941 caactaatcc accaccaata ccctgaagaa aaaagaatca ttctttcaac cgagattact
    21001 ctcacagatt cgatccaaca acaagaaatg tagaacagaa ttataaaaga acagaaacac
    21061 tgaggataag tcagttactc tgttcttttt tcaatcactc atccctcgtt accccctccc
    21121 ggtattttag cgaatttttc ttattttcca tctgttttag atagctgtgg ataactataa
    21181 tgtttgtgtt aaactatttt ttccacaggg aagaaaaaac tatttttaac cacgttgtgt
    21241 ataagttttt atagttcgtt tttttaaaca catttaccct tatttcaatc catgttattt
    21301 ggggatactt atctctaaaa cataaataga ataacagaca tgtctactgg ttttgtttta
    21361 ttcgaggaat tattcaataa tagctagcaa aatattaaaa ataaccgctc tatcttccca
    21421 tcaatttatt ttgcattcaa aaaatgatct atctttactt ttgttgattg acttctcttg
    21481 gaagatgatc gttccgatac cttaattgga tacgaaccga tgttgttaag atcctttccc
    21541 acttttcttc tagttagaca aattatttta gacaaaccaa aaaagaggtt gtgacaataa
    21601 tttgtcacaa cctctttttt aaaatatcta ttttgtttga ttgttcattg cgtcttctgc
    21661 agccatttgc gcttcaatat ctgaaatact gtagacattt tcgcttgcta caccgacttc
    21721 ttttggttcc atgtcacgat aacgttgcat accagtacca gctgggatga tcttacctat
    21781 aataacattt tctttcaaac caagaagagg atctttctta ccgcggatcg cagcatccgt
    21841 caagacacga gttgtttctt ggaatgatgc agcagataag aaactatttg tttctaatga
    21901 tgcttttgtg atacctagta agacaggtcg agaagttgca ggaacgcctc ctgagactag
    21961 cgtattgtag ttttgatctt taaagtctgc gatgtctaat aatgtacctg gtaagatatc
    22021 tgtatcacct ggatccatta cacgaacttt acgcagcatt tgacgaacca ttacttcgat
    22081 atgcttgtcg ccgatttcta ccccttgcat acggtaaaca cgttgtactt cacgaagcaa
    22141 gtagttttca acagataata catcgcgaac ttgcaacaat tgttttggat cgattgatcc
    22201 ttctgtcaat ggtgcaccac ggtggatcat atcgccttct gctactttca tacgtgctgt
    22261 ataaggaaca gtatacgtac gtgtatctgt ttttcctttg attgttactt ctttggtacg
    22321 tgttgcagga tcttctgaga tatcgatgac atcccctgtt acttctgtga tcactgcttg
    22381 ccctttcgga ttacgtgctt caaagatttc ttggacacga ggaagacctt gagtgatatc
    22441 gtctccggca accccacctg tatggaatgt acgcatcgtc aactgagtac caggttcacc
    22501 gattgattga gcggcgatcg taccaactgc ttctccgact tcaacgtcag agccagttgc
    22561 aaggttgcgt ccgtaacaat gtttgcagac accatgtttt gtattacatg tgaagacaga
    22621 acggattgtc actgtttcga cacctgcatc aacgatttgt tttgcgatgt cttcggaaat
    22681 caattggttt cctgcaatga tcaattcatt tgtttcagga tgacgtactt ctttacgggt
    22741 gtaacgtccc actaaacgat cttctaatga ttcgatgatt tcatttccct cgcggatggc
    22801 ttggatttca agacctcggt cagtaccgca atcttcttca cggatgatta catcttgggc
    22861 cacgtcaacc agacgacgag tcaagtaacc tgaatcggca gtcttcaagg ctgtatcggt
    22921 catcccttta cgagccccgt gagttgagat aaacatttcc aagacggata gtccttcacg
    22981 gaagttcgaa atgattggca attccatgat tcgaccatta ggagcggcca tcaaaccacg
    23041 cattccggca agctgtgtaa agttggaaat gttaccacga gctccagaat cagacatcat
    23101 gaagattgga tttttcgctt ccaaaccttc catcagtttt tgttggatgc tgtcttttgc
    23161 agcattccaa acagcaatga cacgttcata acgttcgtca tctgtgatca gaccacgacg
    23221 gaattgtttt gtaatagttt caacttgttt atgggcattt tcaatgattt cttgtttttc
    23281 attcagtaca ctgatgtcag cgatccctac tgtgataccg gcatgtgtcg aatgtttgta
    23341 ccctaagtct ttcatacggt caagcatctt agaagtttct gttactttga atcgtttgaa
    23401 gacttctgcg atgatgtttc ctaagttttt cttcttgaac ggtaatacta attcttgctc
    23461 tttgatatgt gcaggaatat cagtaccagc ttcaacaaag tatttgtccg gtgtttggac
    23521 ggtcaagttg aagtctgttg gttcattcag ataagggaat tcaggaggca tgatctcgtt
    23581 gaagatgatc ttaccaactg ttgtgatcat cgtacgttct ttttgccatt cagtaaatgg
    23641 tttttcacct aatgagttag ggttcacacc gatacgtgaa tgtaaatgaa catatccgtt
    23701 gcgccatgcg ataacggctt cgttttgatc tctgaagacc attccttcgc cttcgcgtcc
    23761 ttcttcttcc attgtcaagt agtagttacc tagaaccata tcttgagaag gagtaacaac
    23821 tggtttacca tctttagggt tcaagatgtt ttgagcagct aacatcaaca tacgtgcttc
    23881 tgcttgtgct tcttcattca atggaacgtg gacagccatt tggtctccat cgaaatcggc
    23941 attataagct tcacatacaa gtggatgcaa acggattgcg cgtccttgta ctaaaactgg
    24001 ttcgaatgct tggataccaa gtcggtgaag cgtaggtgcc cggttcagca atactgggtg
    24061 ttccttgatt acgtcttcta aaacatccca tacttcgtct tcttgacgtt cgattttacg
    24121 tttcgcattt ttgatgtttg aagctagttc gcgttgaaca agctcacgca tcacgaatgg
    24181 tttgaataat tcaatggcca tttcttttgg aagtccacat tggtacatct tcaagaaagg
    24241 tccaacaacg ataacggaac gacctgagta gtcgacacgt ttacctagca agttttgacg
    24301 gaaacgacct tgtttccctt tcaacatatg agaaagagat ttcaatgggc ggttacctgg
    24361 tccagtaact ggacgtccgc gacgaccgtt atcgatcaat gcatctactg cttcttgcag
    24421 catacgtttt tcattttgaa cgatgattcc aggtgcattc aagtctaaca aacgtttcaa
    24481 acggttatta cggttgatta cacgacggta aagatcattc aagtcacttg ttgcaaaacg
    24541 tccaccttct aattgaacca ttgggcgtaa atctggtgga ataacaggga taacgtccat
    24601 aaccatccag cttggttgat ttcctgaagc gcggaatgct tctaaaatat ccaaacggcg
    24661 gattgcacgt gtacgttttt gtccttgtgc agatttcaat tcttctttca attcggctgc
    24721 ttctgcatct agatcaacat tatcaagtaa ttgtttaatc gcttctgcac ccatagcagc
    24781 ttggaattct tgtccatatt gttcacgttt ttcgcgatat tcgcgttctg tcaacaattg
    24841 ttttttctct aaattcgtat ttcctggttc gatgactaca tatgaagcaa aataaatgat
    24901 ttcttccaaa gcgcgtgggc tcatgtctaa tacaagaccc atacgtgaag gaatcccttt
    24961 aaagtaccag atatgtgaaa caggagctgc taattcaata tgtcccatgc gttcacggcg
    25021 aactttcgaa cgagtaactt ccactccgca tcgatcacaa acgattcctt tataacggat
    25081 acgtttgtat tttccgcagg cacattccca gtcttttgta ggaccaaaaa tccgctcaca
    25141 gaacaaccct tcgcgttcag gttttaaggt acgatagtta atcgtctcag gtttttttac
    25201 ttcaccgtaa gaccagcttc tgattttttc gggagaagcc aaacctattt gcatactttc
    25261 gaatttattt acatcgatca aaaggggttc cctccatttc atttaatggc aaaccgcaag
    25321 acggctgatc ttcgaccgcc ttgcagctca tagaccggat tagtctaaat tatcttctgc
    25381 ggtttcaaag ttttggatga catcgtcttt ttcatcttcc acttgttcag cagctttctt
    25441 ttctaattct ttggcagttt gctgttcggc aaattttgtc aaagcatcaa cagtgatcaa
    25501 atcgtcgtct tcatcgtcca tgtcgcgaag ttcgatctct gtttcttcga tatccaagac
    25561 acgcatgtcc agacctagtg attgcaattc tttcaccaat acgcggaatg attccggtac
    25621 acctggtttt ggaattggtt cacccttgac gattgcttcg tatgttttca cacgtccgac
    25681 tacgtcatct gatttgtatg tcaagatttc ttgtaaagta taagccgcac cgtaagcttc
    25741 cagtgcccat acttccattt caccaaaacg ttgtccacca aattgagctt tacctcccaa
    25801 tggttgttgt gtaaccaatg agtaaggtcc gattgaacgt gcatgcaatt tgtcatcgac
    25861 catgtgagca agtttgatca tgtacatcac accgacagac acacgtccat caaatggttc
    25921 acctgtacgt ccgtcgtaca gaacagtttt cgcatcgctg gccataccgg cttcacgaac
    25981 tgtttcccat acgtcttcat cacttgcacc atcaaatact ggcgttgcta cgtggatacc
    26041 taactgacgt gcagccatac ccaagtgtaa ttccaatact tgcccgatgt tcatacgtga
    26101 aggcacccct aaaggattca gcatgatatc gattggtgtt ccatcaggta ggaatggcat
    26161 atcttcttcc ggcataatac gggatacaac ccctttattt ccgtgacgac cggccatttt
    26221 atccccttca tggattttac gtttttgaac gatataaaca cgaactaaca tgtttacgcc
    26281 tggtgacaat tcatctccag cttcacgagt aaagattttc acatcgtgaa cgataccgcc
    26341 gccgccatgt ggtacacgta atgatgtatc gcggacttca cgagcttttt cgccaaagat
    26401 cgcatgcaat agacgttctt ctgcagataa ttctgttacc ccttttggcg tgactttccc
    26461 tacaagcaaa tcgccatctt ggacttctgc accaatacgg atgataccca tttcgtctaa
    26521 atcttttaat gcgtcttccc cgacattagg gatttcgcgt gtgatttctt caggtcctaa
    26581 ttttgtatcg cgggcttctg attcatattc ttcaatatgg atagaagtgt atacgtcatc
    26641 ttttaccaaa cgacggctca tgatgatcgc atcttcatag ttgtaccctt cccaagtcat
    26701 gaaaccaact aaaacgtttt ggcctagagc catttcgcct tgttccatag atggtccgtc
    26761 tgccagagta tccccttttt cgactttctc acccaaatga acgattggac gttggttgta
    26821 gcttgttccg gagtttgaac gacggaattt tgttacatcg tatttatcta atgcaccgtt
    26881 gtcgcggcgt acgcggattt cagaagcatc aacgtattca acgacaccgt catgtttaca
    26941 taacaaagca gctcctgagt catgcgctga tttgtattcc ataccagtac caacccatgg
    27001 tgcttgagga ttgatcaacg gcactgcttg acgctgcatg ttggcaccca tcaaggcacg
    27061 gttggagtca tcgttttcca agaaaggaat acatgctgtc gcaacggcaa ctacttgttt
    27121 aggtgatacg tccatgtagt ctactttatc aatagatact tctaagtttt cactttgagc
    27181 acgagccata acaacgtctt gagcaaatgt tccatcttca ttcaatgggc tgtttgcttg
    27241 ggctacgatg taatggtctt cgatatcagc tgtcaagtag tcgatttggt cagtaacacg
    27301 acctgtttca cggtctacac gacgataagg tgtttcgata aatccgaatt tatttacttt
    27361 cgcataactg gacaaactat tgatcaaccc gatgtttggg ccttcaggag tttcgatcgg
    27421 acacatacgg ccatagtggg agtagtgaac gtcacgaact tcataaccgg cgcggtcacg
    27481 agtcaatccg ccaggtccta aggctgaaag acgacgtttg tgtgtcaatt cgccaagagg
    27541 gtttgtttga tccatgaact gtgacaactg agaagaacca aagaattctt tgatacttgc
    27601 cacaactgga cggatattga tcaattgttg aggtgtcaat gtttcagtat cttggatcga
    27661 cattctttca cgaaccacac gttccatacg tgctagcccg atacggaatt ggttttgtaa
    27721 aagttcaccg actgaacgga tacgacgatt tcctaagtgg tcgatatcat cgacattgcc
    27781 gataccttcc atcaagttca agaaatagct cattgaagca atgatgtcgg ctggacgaac
    27841 cgtttttaca gctgcttctg gatagccgtt tccgatcacg tttacttcac gttcagggtc
    27901 tcttggtgaa aatactttga tgacttggac agtcattgga tctgtgacca caccgtcttc
    27961 tgatggatag taagtcactg aatttaggcc attatcaatg aaaggagcta gtgtttccat
    28021 gacttggtga gtcagaactg ttcctttttc aacgatgatc tcgcctgttt ctggatcaac
    28081 taatgtttca gctaatgtca gattcaatag acgtgttttc aaatctaatt ttttgtttac
    28141 tttgtaacga ccaacgtttg ctaagtcgta acgttttgga tcgaagaaac gagcattcag
    28201 caagttacgt gagctgtctg ctgtttttgg ttcgcctgga cgcaaacgtt cgtaaacgtc
    28261 tttcaaacct tcttctgttc ttgagtcgct tgcgttttta tgcaagtctt tttcgactgt
    28321 attgcgtaat gtttcgctgt cgccgaagat ttcaaagatc gtatcatcgg aaccaaatcc
    28381 taacgcacga actaatacgg ttaaaggaat cttacgtgta cggtcgatac gtacataaga
    28441 gatgtctttt gcatcagttt ccatttctag ccaagctcca cggttaggga taacagtaga
    28501 accgaatcct tcttttccgt ttttgtcgac ttttccatgg aaatagacac ctggtgaacg
    28561 gactaactga gaaacgatta ctcgctctgc cccgttgatg atgaatgttc cttgttctgt
    28621 cattaatggg aaatcaccga agaatacttc ttgtgctttg atttcgccag tctcgcggtt
    28681 tgtcaaacgc aatgttacat gtaatggtgc agagtagttt gcatcatgcg cacgagcttc
    28741 tgctactgta tactttggtt ctttcaattc ataatctaca aattccaaag atagattgcc
    28801 attgaagtca tcgattggca aaatgtcttc aaacatttct ctaagtccct catctaagaa
    28861 ccattggtaa gagtctgttt gaatttcgat caaatttggt aattccaaca cttcactgat
    28921 tcttgcgaaa cttctacgtt cgcgatgttt tccgtatttt actacgtgtc cagccaagct
    28981 cttcacccct ctaaaatgtc attcaaaaag actacccgat caattgttac aataatattt
    29041 caaatattat ttttaggtaa caacagacat tttttgcggc ttttaggcaa aaaaaaacca
    29101 aaaatagaac attctcttga aaccttactt cgtgagcttc tacttttgtt tccttatatt
    29161 aaagccgaaa cggacaatat ttcgtttctg ccttttcttc atcagatagt ttttgcaact
    29221 tcatatacta cacttatttt ctataaaagt caacacttcc tggcgtttct tctgcttttt
    29281 cgcaacattt tcttaatgtt ttcaatttta tgttttcaat tatctgacaa ttcttaattg
    29341 acagaccttt ttatctcggt tatactttag aaaattcatt ttgtggagga acttctatgc
    29401 gaaccaacat caaccaaatc gcaccaacac aactgaataa cttttacttt agctacttta
    29461 gataggtttg tattcatcat gatggataca aacgttaaac gacagtttgt atctatgatg
    29521 gctaaagaac tttgtattgc agcaaaaagc cacgtagaca aaatgctaag tggctgagca
    29581 gtgaaaatac aaagtaaaag tatcaagcat tctacttttt caatttattt tccgactttt
    29641 caatccattt ggacattttg tctgaatgga ttttttgttt cccaaaatta aggaggaaaa
    29701 agaaatgaaa aaaaatataa tcatcggatt aggcgctgcc ctgctactag ctttaggagg
    29761 ttgcgcacaa aaagacaatt ccgcagaggc atcagatgga caaaaaacaa ttggcgtatt
    29821 gcaacttgta caacataact cgttagatgc tgcctataaa ggattcaaag aaggattagc
    29881 agaagaaggg tataaagaag gcgataatct aacaatcgat tatcaaaatg cccaaaacaa
    29941 tcaagacaac ctgaaaagta tgagtgagaa actcgtcaaa gaagatcctg atttgctact
    30001 tggaatcgcc actccagcag cacaatcttt attaaatgaa acaaccacta tcccgatgac
    30061 tgtcacagcg gtcacagact tggaacaagc ccatttagtc acatccaatg aaaaacctgg
    30121 cggcaatgtg actggcacga cagatatggt gccaatcgaa aaacaaatcg gcttactgtt
    30181 aaatatcgtg ccagacgcca aaacaatcgg catcatgtat aacaacggtg aagcaaactc
    30241 taagatccaa gctgatttgg cagaaaaaga attgaaaaaa gcgggcgtca aagtcaaagt
    30301 actgacagca aattccacaa atgatgtcca acaagtgacg aaaagtctag ctaaagatgt
    30361 agatggaatc tatattccta ctgataacac gttcgcaagt gcggcaagtg ttgtcggtga
    30421 agtcgcaaaa gaaacaaaaa cacctgtcgt tgctggcgca gttgatcaag tcaaagacgg
    30481 cggtctagca acagtaggaa tcgactacga aagcttgggc aaacaaacag ggatcatggc
    30541 agcaaaaatc ttagacggca agaatccaag tgaacttcct gtcgaaacag cgaatgattt
    30601 ggaactgtat gtcaataaag acatggccaa agcattaggc atcaatccag acagcatcaa
    30661 agaagctgaa taaaacacag gaggattctc atgacaaatt tgctctctct tttcttatca
    30721 tctgcatcgc aaggggtctt atgggcccta cttgcgattg gtgtatacgt cactttccgt
    30781 atcttggaca ttgccgactt gactgctgaa ggaagctttc ctttaggtgc agggatcgcg
    30841 gcagtaagta ttacaaatgg ctatcatcca ttgacagctt gtcttctagg ctttttaggg
    30901 ggtgcggcag cagggcttgt ttccggactg cttcacacaa aattgaaaat tcccgccctt
    30961 cttgcaggga tcatcaccat gactggttta tattctgtca catcccgtgt gatgggtgcg
    31021 ccgaacatct ctttattggg tcagccaacg atctttcatt gggtcgagtc attcggcata
    31081 acaaaagaca acgctgtact gatcgtcggt ctgctttttg ctttgatcgt tgtatgttta
    31141 cttgttttgt tcttacgtac agaaacagga cttgctattc gtgcaactgg cgataatctg
    31201 gcaatgagcg aagcaaacgg gatcaacaca gataatatga agatcatcgg ttatatgatt
    31261 tctaatggat gcattgctct ttctggctcc ttacttgcgc aaaacaacgg ctttgctgat
    31321 ttaaattctg gtattggaac gatcgtaatt ggacttgctt ctattatcat cgcagaagtt
    31381 ttgttacgta accagccact atttctccgt ctcttgactg tcgttttagg tgcggtcatt
    31441 tatcgtttta ttttagcgtt agtcttcgaa ctgaatgttg aaccaagtga ttcgaaactt
    31501 gcttctgctt tcgtgctagt gatctgtctt tctttcccgc agatccagca aaaattccat
    31561 ttacctcaaa aaaagaaagg cggtagtgtc aaatgaatga cgtcttaaca ttggaaaatc
    31621 tccatcatac ctttgaaaaa ggaacgatca acgaaaatca tgtcctgaaa ggcattaatc
    31681 tttccttaga tcccggcgac ttcgtgacga tcatcggtgg aaatggggct ggtaaatcta
    31741 ctttgctgaa cagcatcgcc ggtacatttt ctgtcgatca gggtcaaatt ttattgaatg
    31801 gaaaaaatat cacgaaaaaa tctgttgtcg aacgttcgaa atccatcagt cgcgtattcc
    31861 aagatcctaa actagggaca gccgttcgtt taacggtaga agaaaatctt gctcttgcta
    31921 tgaaacgagg aaaaaaacgc ggcttcttcc gtggtgtcaa accacaagac cgaacatttt
    31981 tcaaagacca gctggttcgg ctaaatttgg ggttggaaaa tcgtttatcc tcagaaatcg
    32041 gtttgctgtc tggaggacaa cgtcaagcta ttacgttatt gatggccaca ttacagcgtc
    32101 cagaactgat cttattagat gaacacactg cagcgcttga ccctgctact tccaaaacgg
    32161 tgatggaatt gacagaaaag ctgatcactg agcagaatct cactgctttt atggtcactc
    32221 atgacatgga agacgcgatc cgctatggga gtcgactgat catgctgcat caaggaagga
    32281 tcgtcgtaga tatccagcaa gaggaaaaac agcagctcac agtgccccaa ttattagcgt
    32341 tgttcaaaca aaacagcggc acggcattaa aagacgatca agtactttta tcttcataat
    32401 cagaaagagg atgggacaaa aaatgaacgc ccaccctctt cttttttctc tttccttctt
    32461 tcgtttttgc tttatgtatc aaccgttgtt tcttcgaaaa ctattttgtt ctctccttct
    32521 tcctgataga atggatggga aaggagcttg atgccatgac aacgaaagac aaggtacttc
    32581 aattattgaa aaagacacca gattttcttt ccggagaaaa gttggcacag caactggaag
    32641 tttcccggac aagtatttgg aaagccatca aagaattgga aaaggcaggc tatcgttttg
    32701 agcacgggcc tacagggtat cgttacctgc cctctgacgt actagatgca aaagaaatcc
    32761 agcaagagct acggtcgttt attcctgatt tgaaagtaca aacgatgttg acttctgaat
    32821 ctacgatgaa agatgccaaa ctggcagcag ctcaaggaga ttctgtttcg aagttatttg
    32881 ttgctgatac acaagaacaa gctcgtggac gttttggacg gccttttttc gctgaacctg
    32941 gacgaggaat ctacatgagt ctcttgctcc atccagacaa acggtttgat gaattgcctc
    33001 aatatacgat catcgcagcc agtgcctgtg tgaaagccat tgaatctgta accggtcgtt
    33061 ctgcttcgat caaatgggtc aatgatatct acatggatgg aaaaaaagtc tgtgggattt
    33121 tatctgaagc agtcagtgat atggaaagcg gcaggatcag tcatatcatc attgggatcg
    33181 ggcttaattt ttctgttcct caaaatcatt ttccagctga tctccaagaa aaagccatct
    33241 ctgtctttcc cgacggacaa gctagtgtca caaggaatca gctaatcagc aaaatctggc
    33301 aagaattgtt cacttatctt tctcacccag aaaaagcgtt ggacttctat aaagaaaaat
    33361 cattcgtatt gggaaaaacc gtgtcgttca atcaaaaagg aacgacttat gtcggtcttg
    33421 caaaagaaat cggtgatcat ggcgaactga tcgtccaaac aaatgaacag aagatgagtt
    33481 tgtcttctgg cgaaatcagt ctcacatcta tccgtacgca ataattatca gatttcacaa
    33541 aaggacacct gatctcatac agtgtccttt tttctgaatt ctcttcaaaa gactctcctt
    33601 attctatcag ctgacagttt ctctatcctc tagaaaaagg tattctaaaa atatctataa
    33661 agcatggtac actttcttta aatgaatcaa tgcaaaaaac aagagagtca tcagtttaca
    33721 cgatcaaaag agatagcagg ccgcttcctt tttcaatctt atagatagac catgggtaac
    33781 gataaaaaca aaaaagaact tgcgacttat tttgccgtaa gttctttttt agctagtgcc
    33841 ttaatctctt aatcccaaca aacgtctcgc atagatcacc tgaccagagt gcatagcagc
    33901 atcatcaata atagaaacga gacgcattcc tcgtgtgact ggtggtgtcc agttctcgtc
    33961 aattacttca tctagctcgg aaggttccag ccttcttaag taagaaatag caaaatcagc
    34021 agctcctcgc aagtatccta gcagatcttc tatttgatta gcttggatct gctttgcttg
    34081 ttccagacta tgcttccaat cttgttcgtt atctgctatc gtcatcggaa accggctttc
    34141 ccagtcttga ctatgccaaa ttggagaagt tcctgctaaa tcagcaatct ggaaatctaa
    34201 ttctcgagcg gtatgccaag ccagccaagt cattgatttg atctgcgggg ctctatcttc
    34261 cactggaaaa cgattggcct cctcaataga gacgccttca aacaaacgtt caaaccgatc
    34321 gtatgcccga tccacactct cgcatagcat atctaaataa tccatttatt ttcctccttt
    34381 ttatttatcc tacttacttt ttcctaattc taggatacct acttatatgt tactacacac
    34441 ccttattttt tacactttaa cagtcaccat catcaatagt ttggagattg aaagaaaaag
    34501 atagtgtcga actatcaatt gaacaagaag caacaatatg aacgtttcat taatattctt
    34561 taaataaaca atgatttttc aaacgaacag tttaagacta ggagaaaaag agtataatag
    34621 gaaaatgttt gaaaggaaag gaaggggaaa aatgaaaaaa agggcaagtt tactagtcct
    34681 agttgctttg ttgttcaata tcttttcgta tggtgtggcc gtttcagcgg aaacatacat
    34741 tcctaaagac cctgggaata tttataatga tctaactggt aactatggct tgttaggaat
    34801 tgctagtcaa ttccacgtat ttgctaaaaa taagacaact gtgaatgcac atacagacgg
    34861 aaatatagca acacatgaac ttgatgcaaa aaataatttt ggtacagagc ttcatgaagg
    34921 tttattgaac caagaaataa attatataca aaaaactgat tctttcgcta attcttcagg
    34981 catacctaca ggtagcacaa gaatgaataa atttgtcgtt ggcagtaacg tggatgtagc
    35041 acttcaagat ggtcatccta cagtcaatgg atccaggctt gatcacttaa ctccagatga
    35101 tttttataaa gatcgtgctg ggcatgaata tattgatttc gagcaggaat ttgctaaatt
    35161 gaatgtagca gcaaatgatc ttgcaacgat cactccagct aaaacatata ctgctgcaga
    35221 ttttccagac atgaacaatc ggacaatcga tttaactgat ttatcagata ccgggttttt
    35281 attggtaaat atcgatgcag aagtgttaac gatgaatacg ccacttcaaa tcattaatcc
    35341 aaatgatcaa gtagttgtat ttaatgtcat caacagttct tctgcattga acgtacagtc
    35401 accaatcaaa tacaatgatc gttcaaatca tgaaacagaa gatttttcgg atgcgaatat
    35461 ctcttggaat tttggaaatg agatgactga tttgacaatc agtgctcctt ttcaaggaac
    35521 aatccttgcg cctaatgcta ctatccgcat tactcaaaac caagacggaa cgattatagg
    35581 aacaaatgtg attttagatg cagctaccaa tcgttgggat cctaacgaaa tatttatcag
    35641 cgacaatggt acagatacga cagacacaag cgacagtaca gatacatcta ccacaagtga
    35701 tagctcagat tcatcaactt caagcgacag tacagatact acctctacca caagtgatag
    35761 cacggataca tcagcttcaa gcgacagtac agatac
//
LOCUS       DAFBVQ010000024        35019 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.024, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000024 DAFBVQ010000000
VERSION     DAFBVQ010000024.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 35019)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 35019)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..35019
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.024"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(56..2653)
                     /gene="adhE"
                     /locus_tag="LLC22_001350"
                     /gene_synonym="adhC"
     CDS             complement(56..2653)
                     /gene="adhE"
                     /locus_tag="LLC22_001350"
                     /gene_synonym="adhC"
                     /EC_number="1.1.1.1"
                     /EC_number="1.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional acetaldehyde-CoA/alcohol
                     dehydrogenase"
                     /protein_id="HBK5434635.1"
                     /translation="MAKVIEKEKTKTIDVQAMIDDLAEKANAALKEMESFDQEKVDHI
                     VHEMAMAALDQHMPLAKMAVEETGRGVYEDKAIKNMYASEYIWHNIKHDKTVGVINED
                     VQKGLIEIAEPVGVVCGVTPTTNPTSTTIFKSMIALKTRNPIVFAFHPSAQKSSAEAA
                     RVVRDAAIAAGAPENCIQWIEHPSIEATSMLMNHPGIAIVLATGGAGMVKSAYSTGKP
                     ALGVGPGNVPAYIEKTAKIKRAVNDLIVSKTFDNGMICASEQAVIVDKEIYAAVKAEF
                     QAHQVYIVKPDELQKLEDAVMNEGKYAVNPSIVGHSAMEIAKLAGISVPKGTKMLIAE
                     LEGVGPDYPLSREKLSPVLAMIKANNTDHAFDLCEGMLNLGGLGHTAVIHSENEELHV
                     KFGLRMKACRILVNTPSAEGGIGDIYNEMIPSLTLGCGSYGKNSVSRNVSAVNLINVK
                     TVAKRRNNMQWFKLPPKIFFEKNSLLYLEKMENVERVMIVCDPGMVQFGYCDTVREVL
                     ARRKNDVKIEVFSDVEPNPSTNTVYAGTKLMADFKPDTVIALGGGSAMDAAKGMWMFY
                     EHPDTSFFGAKQKFLDIRKRTYKIDKPEKTQFVCIPTTSGTGSEVTPFAVITDSETHV
                     KYPLADYALTPDVAIVDPQFVMSVPASVTADTGMDVLTHAIESYVSVMASDYTRGLSL
                     QAIKLVFDYLEKSVKTPDMESREKMHNASTMAGMAFANAFLGICHSVAHKIGGEYGIP
                     HGRTNAILLPHIIRYNAKDPQKHAMFPKYDYFRADTDYADIAKFLGLKGETTEELVEA
                     LATAVYELGKSVGINMSLKAQGVTQETLDTTVDRMAELAYEDQCTTANPKEPLISELK
                     QIIIDAYNG"
     gene            complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="LLC22_001351"
     CDS             complement(2958..3338)
                     /gene="yajC"
                     /locus_tag="LLC22_001351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit YajC"
                     /protein_id="HBK5434636.1"
                     /translation="MGTLPMLVMFIALLAMWFFMSRSQKKQQQERQNLLDSMKPGDSV
                     VTIGGLHGVVSEIDNDKRTVVLDCEGIFLEYDRAAIKTVKPGTVVTNDATTTVETTEE
                     PAETVEVKTETTETLEETEEKEEK"
     gene            complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="LLC22_001352"
     CDS             complement(3435..4580)
                     /gene="tgt"
                     /locus_tag="LLC22_001352"
                     /EC_number="2.4.2.29"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720296.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA guanosine(34) transglycosylase Tgt"
                     /protein_id="HBK5434637.1"
                     /translation="MTQPAIRYRLIKKEKHTGARLGELITPHGTFPTPMFMPVGTLAT
                     VKTMSPEELKEMGAGVILSNTYHLWLRPGEDLVEEAGGLHKFMNWDQPILTDSGGFQV
                     FSLSDMRNIEEEGVHFKNHLNGSRMFLSPEKAINIQNKLGSDIMMSFDECPPFDESYD
                     YVKKSVERTSRWAERGLKAHANPDRQGLFGIIQGAGFEDLRRQSAKDLVGMDFPGYSI
                     GGLSVGEPKSEMNRVLEFTTPLIPENKPRYLMGVGAADSLIDGVIRGVDMFDCVLPTR
                     IARNGTCMTSQGRLVVKNAKYAHDFRPIDEKCDCYTCKNYTRAYIRHLIKCDETFGIR
                     LTSYHNLYFLLNLMKQVRQAIMDDNLLEFREAFFEEYGFNKENAKSF"
     gene            4798..5496
                     /locus_tag="LLC22_001353"
     CDS             4798..5496
                     /locus_tag="LLC22_001353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBK5434638.1"
                     /translation="MQSSAELKRQAKESLKGRWGQAVLLNLIPTLIGIATILLIMIPI
                     ILFATTIYDGSASVSEATTSGGGSSGGGGGIISSIISALFMSGISWTYLDILRGQKDQ
                     IEPFKDAFRGFKGLFIGGVISLAVLISIFTTLWGLLLVIPGIIKSYSYSQSYFIYYDI
                     VQETGQTPKVLDTITASRKLMDGYKGQLFWLDLSFIGWHILALATAGIGYLWLSPYIS
                     ATKAAFYEQLPKDI"
     gene            complement(5664..8303)
                     /locus_tag="LLC22_001354"
     CDS             complement(5664..8303)
                     /locus_tag="LLC22_001354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5434639.1"
                     /translation="MEEYKQTIEEVKKVTEADPDTGLSSQEVDERRKKQGLNKFDEAP
                     KESMIKKFFRSLSDFTTIILLVAAVISFYTAFATEHGDLFEGLLIIAIVVINSVLAIV
                     QEGNAEKALESLQDMNKQTATVIRDGKVTTVESEQLVVGDILVLESGDAISADARLIE
                     ASQLRVEESALTGESEAVEKDAAFIAEEDESLGDQLNMVFKGCTVAAGRGKAIVTAIG
                     MATEMGKIADLLNENTMQKTPLQVRLNQLGKRISMIALAAAALVFVIGELQGEPLLEM
                     FMTSISLAVAAVPETLTVIVTLTLAYGVQKMARKHAIIRQLPAVETLGTANVICSDKT
                     GTLTQNEMRVRRVWSKEDEVTNIEDSMTNSAMEILKMAALCTDVTVEQEDDDLVIKGN
                     PTEVAIVRAVEENYHTKAELEEKYPRVNELPFDSERKMMTTVHQMGEKYISITKGAFD
                     VLAPRFSSGDVEQAAIVNDRFGKRALRVIAVGYATYDEEPQDISSEALEKDLRLIGLI
                     GMIDPPRPESKGAIKRAKKAGIKTVMITGDHVVTASAIAKELGILNDPSEALSGSELH
                     QLSDEELDARVKALSVYARVTPEDKIRIVKSWQRTGAVVAMTGDGVNDAPALKASNVG
                     CAMGITGTDVAQSAADMILTDDNFATIVDAVSQGRSVYQNIRKAINFLLSCNISEIFI
                     VLIAMLLGWGAPFTAVQLLFVNVVADGLPGFALGREPAEHGIMDQPPIPKNEGIFARG
                     LLQKIAINAGVFTIVTLFGYYLGSYVDTISPWVDASQHVGQTVAFLILAYSSILHVFN
                     VRSSQSIFKVNLATNKALVEMALLALAITTAVALLPFTQELFGLVHISLNHWFLVGIL
                     SIVPIAVNELIKFHRLPEAEEEE"
     gene            complement(8922..9953)
                     /gene="queA"
                     /locus_tag="LLC22_001355"
     CDS             complement(8922..9953)
                     /gene="queA"
                     /locus_tag="LLC22_001355"
                     /EC_number="2.4.99.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA preQ1(34) S-adenosylmethionine
                     ribosyltransferase-isomerase QueA"
                     /protein_id="HBK5434640.1"
                     /translation="MLTTEDFDFDLPEELIAQTPLKDRDHSRLLVLDRKTGEMEDKHF
                     HEIIEELQPGDALVMNNTRVLPARLYGEKPDTGAHLEVLLLTNTQGDTWETLIKPAKR
                     AKVGTRISFGDGRLQAVVKEELEHGGRIIDFEYEGIFLEILESLGEMPLPPYIKERLE
                     DPDRYQTVYAKENGSAAAPTAGLHFTKELLDEIEAKGVELVYLTLHVGLGTFRPVSVD
                     KIEEHHMHSEFYRLTEEAAERLNQVRKNGGKIVAVGTTSIRTLETIGTKFNGEIKADS
                     GWTDIFITPGYEFKVVEAFSTNFHLPKSTLVMLVSAFAGRELTLSAYQHAIEERYRFF
                     SFGDAMFVK"
     gene            10146..11321
                     /locus_tag="LLC22_001356"
     CDS             10146..11321
                     /locus_tag="LLC22_001356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628506.1"
                     /note="Members of the family are the ATP-binding subunit
                     of ABC transporters for substrates such as betaine,
                     L-proline or other amino acids, choline, carnitine, etc.
                     The substrate specificity is best determined from the
                     substrate-binding subunit, rather than this subunit, as it
                     interacts with the permease subunit and not with substrate
                     directly; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="betaine/proline/choline family ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5434641.1"
                     /translation="MIEFQNVSKIYKGGKVAVEDVNLSFEKGEFICFIGTSGSGKTTT
                     MRMINRMTDPTQGKILIDGKSIQEIDPVELRRQIGYVIQSIGLMPHMTIRENITLVQK
                     LLKVSQEERNKTAEKMIDLVELPREMLDRYPHELSGGQQQRIGVVRALAANQDIILMD
                     EPFGALDPITRDSLQDLVKDLQERLGKTIVFVTHDMDEAIKLASRIAIMSEGRVIQFD
                     TPENILRHPANDFVEELIGEDRLLQAKPNATRVGEVMLNTAITITPEKSLQEAIKLMR
                     EKRVDTLLVTDNSNVLKGFIDVETLNKKRGKVSSVGDILNKHVFYVKESAYLRDTLQR
                     ILKRGLKYVPVVDEQNKVVGILTRASLVDIVYDVIWGEDPATTDVAESATPEESKEV"
     gene            11325..11966
                     /locus_tag="LLC22_001357"
     CDS             11325..11966
                     /locus_tag="LLC22_001357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434642.1"
                     /translation="MQQFFHQHGSEILSKGFEHLYISGLALIIGIIIAVPLGVLLTRF
                     PKAATIVIGLTSALQTIPSLALLALMIPLFGVGKLPAIIALFIYSLLPILRNTYIGMK
                     NVDWNYRDVAKGMGMTEFQSIFSVELPIAMPTIMAGIRLAAVYVIAWATLASYIGAGG
                     LGDLIFSGLNNYQPDLILAGTIPVTILALLADWLLGLLEHRLTPIALREENEE"
     gene            11963..12880
                     /locus_tag="LLC22_001358"
     CDS             11963..12880
                     /locus_tag="LLC22_001358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="osmoprotectant ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5434643.1"
                     /translation="MKRILKMTMVLFSLLILASCSFPGLASNTDEDTISITGGITSEA
                     QILASLVAGMVEHYTDKNTAIINNLATTTINHQAMMNGDASISAARYTGTDLTTTLNL
                     PPEKDPKKAFATVKDEFEKRYGQTWFPSYGFENTYVFLVRKDTAQKYHLSKVSDLKNV
                     ADELVAGVDTSWINRKGDGYDGFQETYGFSFNSILPMQIGLVYDAVEAGKMDIVLGYS
                     TDGRIASYDLVMLEDDRQFFPPYDAAPVVDNKILADTPHLKEALNKLGHTISTEKMQE
                     LNYEADNNLVEPSVVAQRFLQENHYFEGK"
     gene            12877..13548
                     /locus_tag="LLC22_001359"
     CDS             12877..13548
                     /locus_tag="LLC22_001359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434644.1"
                     /translation="MKQLDKMNVFQQFFYYFQENGSYIFAQFIRHFLISIYGVLFAAV
                     VGIPVGIMISRRRKLANWVIRLANIIQTIPSLAMISILIIGLGLGVNVVIVTVFLYSL
                     LPIIKNTYTGMIQVDKNILDVGKGMGMTARQRLFMVELPLSVSVIMAGIRNALVVAIG
                     ITAIGAFVGAGGLGDIIIRGTNATEGTSIILAGALPTALMAIITDWLLGILERRLDPA
                     SRTSR"
     gene            complement(14089..14577)
                     /locus_tag="LLC22_001360"
     CDS             complement(14089..14577)
                     /locus_tag="LLC22_001360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannosyl-glycoprotein
                     endo-beta-N-acetylglucosamidase"
                     /protein_id="HBK5434645.1"
                     /translation="MTRKISKIGASLLVLAVATTIDYRQSEAKTIGNVVYRETAKSML
                     KKAMDNQPESSYWFPEDSLAWSFGKDTDTKYNTSVVPLAERVSKATLPNMNVTQTEEV
                     KVVALSAMNSSINGNASRGIDIFYANVFSYWQYIDQLVYGGALLVKDHRIAKSSCDGC
                     SP"
     gene            complement(14778..15044)
                     /locus_tag="LLC22_001361"
     CDS             complement(14778..15044)
                     /locus_tag="LLC22_001361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319468.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBK5434646.1"
                     /translation="MSNYTVAIKNSAKVDLRKIKQTNLKKQFEEVIQTLKEDPYMPTQ
                     SFEKLRPTHEGRYSRRLNRQHRVVYKVDEENKVVEIYSAWTHYE"
     gene            complement(15044..15307)
                     /locus_tag="LLC22_001362"
     CDS             complement(15044..15307)
                     /locus_tag="LLC22_001362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294199.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5434647.1"
                     /translation="MANTTMNPSTARKNFYQLLKEVNENHTEIEIISDRSGNNAVLIG
                     LEDWRAIQETLFLEQTGTLDKVRDREKDDSSFTNIDDIDWEAL"
     gene            15783..15968
                     /locus_tag="LLC22_001363"
     CDS             15783..15968
                     /locus_tag="LLC22_001363"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK5434648.1"
                     /translation="MALSYGNKKWSLDEAEIPTYEDTWHLRVEVKEEAENIGGCTLFG
                     KGFGNYDQDIKIKMFYS"
     gene            complement(16110..17933)
                     /locus_tag="LLC22_001364"
     CDS             complement(16110..17933)
                     /locus_tag="LLC22_001364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="APC family permease"
                     /protein_id="HBK5434649.1"
                     /translation="MDYLKRLLVGKPLKSAENDEHKLTRFAALALLSSDALSSIAYGT
                     EQIVVVLVALSAAAIWYSLPIAAFVIILLISLTLSYRQIIHAYPHGGGAYVVSSENLG
                     KNAGLISGGSLLIDYMLTVAVSVSAGAEAITSAVPALYGHQVAISVTIVLLLMMLNLR
                     GLRESASFLLFPVYTFILVISLLIVVGLYNIVTGAVPLQATALPGAAVPGVSIALILR
                     AFSSGSSSLTGVEAISNAVPFFKKPRAKNAAATLTMMALILGFFFVGITFINYWYGIV
                     PEKEVTVLSQIGKAVFGHGILYYVLQFATALILAVAANTGFSAFPVLAYNLAKDKFMP
                     HMYQDRGDRLGYSNGIITLALGSIVLLFIFHGSTERLIPLYSIGVFIPFALSQTGMVV
                     KWKKEGKRWLSKSIANITGAFISYAIIAILFVYRLGDIWPFFIIMPIVMFIFYKIHDH
                     YKKVAEQLRLENDAKLHDYDGNTVLVLVGNVTRVNIGALNYARSIGDYVVAMHVSLDE
                     DVEKEKEIEAEFKKHFPDVRFSIVHSSYRSIENPIIRYVDIVSKNAAKQNYTTTVLIP
                     QFVPNRRWQNILHNQTSLRLRLRLSWRENIVVSTYSYHLKK"
     gene            complement(18531..21236)
                     /locus_tag="LLC22_001365"
     CDS             complement(18531..21236)
                     /locus_tag="LLC22_001365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YhgE/Pip domain-containing protein"
                     /protein_id="HBK5434650.1"
                     /translation="MQSIKNTLRLYLLDWKRIFKNPIATLLIIAIMIIPSLYAWFNIK
                     ALWDPYGNTGELPIAVYSADKPAEFQGKEVAIGEQVIESLHKNKQLGWQFVDSKEQLE
                     DGVRSGKYYAGIYLPKDFSEDLLSFTSGDIKKPKIEYTVNEKINAIAPKITDKGASSI
                     QSQITNEFIKTASSTLLKVFNEIGYDIDTNLVSINKVKDMILSTDENLDTIDGYTKQV
                     LELQSQLPEIKEKLNKANEFVDYIPKVDEMGEKVVALNDKMPELKDQAKIILDLQEKI
                     PEIQNAGKQLAEIDGDFASIQETMNQGIDEAKQGLTIIQQVQDILPDVKNLENQASDL
                     ANQTKSGASQLKDAIPSITNSVDVTLKSIGQVATTTGSLIDTVRTAIEDGKLTDDEKK
                     NISNVLNGFIDGISQQQNAIDKLVEFLTKLQTSAGNTKLQPIIDQLNQLKPLLSNLQN
                     RLSALNTAVQNEDTKAIDELLDQIDAVVNNINGIIAGINTGQISSTVTSLLDQVIDTI
                     GTAQGALSKADQIDFDSLLSSTKATVTNAVAILEKYQKEMPAIGQEIHDANTMLNGNM
                     DTIVNGINEGADLYNNELPIIQQKLGLAADFIQNDWPALKNEITGTLTTVNEKMPEVE
                     TAVNAAADLINNDWPNIKAGIQKAADAIRKGEQEVDLGEVIKLLKLDATKESDFFTQP
                     VELQTNALYPIANNGSASTPFYTALCLWVGAVLLSSVATTEYYLGKKDRNNFTKREQF
                     VARMLTFLTMAIAQSLIVTLGNIFLLGVDVQNPVYSVSFAVLIALAFMMIVYVLAALF
                     DNVGKGIAIIILVLSISGGGGNYPIQVSGKFFQMINPFLPFTHAVNLLRESAGGIYWP
                     NATKAIWIMIGLFVVFGIVGTAIYPFIEEKMTKFKEAAHESHIFH"
     gene            complement(21542..22489)
                     /locus_tag="LLC22_001366"
     CDS             complement(21542..22489)
                     /locus_tag="LLC22_001366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent oxidoreductase"
                     /protein_id="HBK5434651.1"
                     /translation="MRRFAINGYGEAQDVFEEIDAHPREVGSGHVRVEIKAFSVNPYD
                     VALRLGEMKEIRTLKFPYVPGNDGAGIVTEIGSDVTTVHVGDRVAVHAVGGTYGEEVV
                     LPSAKVAKIPDKMSWEEAAGMVTPGITAYNLINHLTEIQPTDTVMILGASGAVGSSLI
                     QLLHEKGIRILTSASSKNEEKVKKLGASAFAAYDKTNPGLQFADQADLVIDATKGSIK
                     GETGIQIMKPGGRYVALNDLPDLDLRQKKEGFYESFVPRKEYLDAEAFAGIIKAYQKG
                     AFHVFISMNLSASLKHVIQAHQLVEGHPPAGKIILSFEK"
     gene            22679..22948
                     /gene="rpsN"
                     /locus_tag="LLC22_001367"
     CDS             22679..22948
                     /gene="rpsN"
                     /locus_tag="LLC22_001367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBK5434652.1"
                     /translation="MAKKSKIAKAKKQQETIERYAALRQELKAQKDYEGLRKLPLDAR
                     PERLKNRDLIDGRPRGYMRKFGMSRIKFRELAHKGLIPGVKKASW"
     gene            complement(23124..23486)
                     /locus_tag="LLC22_001368"
     CDS             complement(23124..23486)
                     /locus_tag="LLC22_001368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBK5434653.1"
                     /translation="MVKRGDIYFADLSPVVGSEQGGTRPVLVIQNNLGNHFSPTIIVA
                     AITAKMAKPKLPTHIGIKATGTGIERDSVILLEQIRTIDKSRLKEKVCHLDRPIMAEV
                     DRALKISVGIEALTPVTK"
     gene            complement(23497..24618)
                     /locus_tag="LLC22_001369"
     CDS             complement(23497..24618)
                     /locus_tag="LLC22_001369"
                     /EC_number="5.1.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alanine racemase"
                     /protein_id="HBK5434654.1"
                     /translation="MVVAWHRPTKAVIHKKAITENVANEVARLPQGKELFAVVKANGY
                     GHGAIETAEAAVAGGASGFCVSNLDEGVELREAGFTQPILILNMVPYDALTVAVAHDL
                     SVTAGTREWLQAAAAVLEKSKLETPLSIHLKADTGMGRIGFCTPEEVKEAAAFIKESR
                     VLEWEGLFTHFSTADQADDTYWNLQKERFIEVLKKLPELPRYVHVSNSATALWHDETI
                     GNMIRYGVAMYGLNPSGHALPEVYPLQPALELVSELIQVKKLPAGEGIGYGETYITPE
                     AEWIGTIPIGYADGWPRKMQGFSLLVEGNYCETIGRVCMDQLMIRLPQEFPVGTKVTL
                     IGKNADKEITMQDIADQLGTIHYEVACGLGQRIPREYQE"
     gene            complement(24634..24984)
                     /locus_tag="LLC22_001370"
     CDS             complement(24634..24984)
                     /locus_tag="LLC22_001370"
                     /EC_number="2.7.8.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="holo-ACP synthase"
                     /protein_id="HBK5434655.1"
                     /translation="MIKGIGIDAVELPRITRLIEEKPKFIARILTSDEMKLFQSLPFH
                     RQVEFLGGRYACKEAFSKAWGTGIGKVTFQDVEILKNENGQPVVTRSPHEGNVWVSIT
                     HTNETAFAQIILED"
     gene            complement(25114..26625)
                     /locus_tag="LLC22_001371"
     CDS             complement(25114..26625)
                     /locus_tag="LLC22_001371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623717.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase"
                     /protein_id="HBK5434656.1"
                     /translation="MKFKELELSPELLKSVERAGFEEATPIQAETIPLALAGKDVIGQ
                     AQTGTGKTAAFGLPMLEKIDPDRHELQGLVIAPTRELAIQTQEELYRLGRDKKVRVQA
                     VYGGADIGRQIRGLKDRPHIVVGTPGRMLDHINRHTLKLGTVQTLVLDEADEMLNMGF
                     LEDIEKIISQVPDQRQTLLFSATMPPAIKNIGVKFMKNPHHVKIKAKEMTADLIDQYY
                     VRAKEYEKFDIMTRLFDVQTPELTIVFGRTKRRVDELARGLEARGYRAEGIHGDLSQQ
                     KRMSVLRSFKSGHLDILVATDVAARGLDISGVTHVYNYDIPQDPESYVHRIGRTGRAG
                     KGGMSVTFVTPNEMDYLHVIENLTKKRMTTLRPPTEKEAFKGQLGAAVEQIETKLAEN
                     GLDKYLQTADKLLEEYSAQDLVALLLKTTAKDPADAVPVKITPERPLPMQKKGYNKNG
                     KRGGGNNRNRRDGGNYRGNKSKGGYSKNNNSQKDGGKRHNDKKRGFVIRSNND"
     gene            complement(26947..28299)
                     /locus_tag="LLC22_001372"
     CDS             complement(26947..28299)
                     /locus_tag="LLC22_001372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-
                     alanine ligase"
                     /protein_id="HBK5434657.1"
                     /translation="MNLTIQEIAQAVGSECSALTKITNVEFDSRKITEGSLFVPLAGT
                     RDGHEFIQQAITNGASASFWSLPVEQAPKNFPVIPVADPLKAMQQLATYYLEKVGAEV
                     VAITGSNGKTTTKDLTASVLSEKYKTYKTQGNYNNNIGLPYTILHMPQDTEKIVLEMG
                     MDHANEITELSLMAQPKAAAITMIGEAHIENLGSREGIAKAKMEITDGLVSDGLLVVP
                     ADEPLLTPLTATLVQTVTTFGIGNGDVHAEVTAKGKAQTDFVVEGETFTIPLPGSYNV
                     TNALIAYTIGRFFGLSIPEIRQGLAHVSITQNRTEWLTAGNGAAILSDVYNANPTAMG
                     LVLDTFKNLPTKGRRIAVLADMLELGKESLNMHAQMSEHIDPEKFAMIFLYGEQMHAL
                     KEELNQKYPQLPVFYFEKEKNKLIDAIKQNLAATDSIMLKGSNSMGLFEVVEQLQQMK
                     "
     gene            complement(28452..29528)
                     /locus_tag="LLC22_001373"
     CDS             complement(28452..29528)
                     /locus_tag="LLC22_001373"
                     /EC_number="6.3.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736859.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanine--D-alanine ligase"
                     /protein_id="HBK5434658.1"
                     /translation="MKITLLYGGRSAEHEVSILSAFSVLNAIYYNYYQVQLVFITKEG
                     QWVKGPLLTEKPASKDVLHLSWDPSGQTEEGFTGKVINPGEIKEEGAIVFPVLHGPNG
                     EDGTIQGFLETLNMPYVGAGVLTSACAMDKIMTKYILQAAGVPQVPYVPVLKNQWKEN
                     PKKVFDQCEGSLLYPMFVKPANMGSSVGITKAENREELQNALATAYQYDSRAIVEQGI
                     EAREIEVAVLGNEDVRTTLPGEVVKDVAFYDYEAKYINNKIEMQIPAEVPEEVYQKAQ
                     EYAKLAYTMLGGSGLSRCDFFLTNKNELFLNELNSMPGFTEFSMYPLLWENMGLKYGD
                     LIEELIQLGMNRYHQRQSFFEKNE"
     gene            29724..31469
                     /locus_tag="LLC22_001374"
     CDS             29724..31469
                     /locus_tag="LLC22_001374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342755.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AarF/ABC1/UbiB kinase family protein"
                     /protein_id="HBK5434659.1"
                     /translation="MAQTNPRSRLAEIIRVFINYNVVPNFVQQKNPEQVKKAFEELGP
                     TFIKIGQMLSVREDLLSSAFTQTFKTLQDSVPSDTFSTVKKTIETELSLSLSDIFDDF
                     SKSPFASASMGQAHRAKLKNGDAVVVKIQHPNIAEEIRLDLQLFERAIPLIKYIPETS
                     VVDLKGVLQEVKRSLINEMDFLKESQNGEQFYQKNNGWKEIRSPKIYDAFCSKKVIVM
                     EEMSGKNLNHLMNAENKTETFITGIQNKQLKQEVAKLLVENFMKQVFDDGFFHADPHP
                     GNLLFHVLTKEEQTQASRKTETVHEKEFGSFAFRASTSAEDPVAPYTINYIDFGMMGH
                     LSAGLRQKLTQAVLALYTKDAYRIEKAVLRLCQQEGSFDESRFHQELTSFLEQYYDSP
                     IDEINLQEVFTHVVTICHQNNLQFDRDITLLLKAFGTLEGVIRVLDPEVSLMEVASPF
                     AQHYFLTHLDVEDTLKQSGLDLLEGMKAAPKIPQQLHHLLEMWTSGQGKVNLELKKQD
                     KLLSRIESMINRLVFGMILAALIVGSSLLVQAAPVENAEVVSLLGIFTYAIAAFVIIF
                     LAIDALIQMYKKRKK"
     gene            complement(31749..32186)
                     /locus_tag="LLC22_001375"
     CDS             complement(31749..32186)
                     /locus_tag="LLC22_001375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YaiI/YqxD family protein"
                     /protein_id="HBK5434660.1"
                     /translation="MRLFIDGDGSPVKEDVIKLGESYGLDVVIVTSVDHYTTKEYANH
                     VQIVYVDRGADSADYKIVGMVKKNDFLITQDYGLASLVLPKGVRVFHHSGKEFDEANI
                     GTLLEQRYHSGKLRKAGIRTKGPKPFTEKDHMSFRQALKKAID"
     gene            complement(32170..33543)
                     /locus_tag="LLC22_001376"
     CDS             complement(32170..33543)
                     /locus_tag="LLC22_001376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434661.1"
                     /translation="MFEKLKRFGRNFTQTTPFILSNTVIFIPYLLFLGLTDSHNWLTI
                     LPFTLFYAFRMTGLFLVNSLRFGLDSYTLLMIALLIGGAGSLLGILGVFYFPLFYFSS
                     VLLGLSAAWLVPANTTVNFHEKTQGFINMDGKKYLFAAIWLFLLYQAIELPAPTQIAA
                     SFTIYTLFYVMAYHTVSHYPRYELDFKDIKRNLVATRELVLFLIFFGLLFLLRNARLL
                     FDERLFDLAIYGFLLLFILFVFVLGHQKKEWKLPSWLNLFTFLNGMLGNFLFLFSSFY
                     VGILYGLEKLSIFMYLPYAAGLIAAKIVGPWILKRLTWSPLAMQLLGLSSSLLVLLIP
                     NGFAIGVFLLSFWHVVTGSWLNKEYYQTDTAIPMDRRIVVKYTTQNKGSVIHQFLLMT
                     LLFVLAKEMGEPIHLLLITLNHESVPIESVQLLILAKWINVGLLLSGLVTVYHLWKKA
                     KKNEAIH"
     gene            complement(33865..34353)
                     /locus_tag="LLC22_001377"
     CDS             complement(33865..34353)
                     /locus_tag="LLC22_001377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434662.1"
                     /translation="MEKIKVTENELDELMAVIQEVWPEAFVPIIGQKQVDYMLKTYQS
                     KKQIQKELTEGVSYFLLKSEEKTVGYTAYEEINGKIYLSKLYLLNKVRGQGLTSSVFR
                     WYEELAAQTKEREIFLRVNQGNHQAIEVYKHEGFEITEELISDIGQGFQMVDYKMKKA
                     LA"
     gene            complement(34375..34977)
                     /locus_tag="LLC22_001378"
     CDS             complement(34375..34977)
                     /locus_tag="LLC22_001378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK5434663.1"
                     /translation="MSKKGSVLQKCLQIMPIIGLFFFFVLILYAYHHGIFRSSTSLQA
                     FIQQFGKYAVMIFVLLQVIQVIIPILPGGISSVAGMLMFGNGFGLLYSCIGLVIGEAI
                     GFLLVRYYGVAFVQLILSPKKYQKFDELLTRKTKDIKKVLVVTLLLPFAPDDLICLVA
                     GLTKLSFREFMQIVIFLKPWSVGVYSMIMLFLFHQAQGHL"
BASE COUNT         9919 a         7476 c         6466 g        11158 t
ORIGIN      
        1 ttttccaagt tctttttcat ctattttctt atcttttttc tacgctttct tttgcttatc
       61 cgttgtaagc atcaatgatg atctgtttca attcagagat caatggttct ttcggattag
      121 ctgtcgtaca ttggtcttcg taagctaatt cagccatacg gtctacggtt gtatctagtg
      181 tttcttgtgt gactccttga gcttttagac tcatgttgat gccgacagat tttcctaatt
      241 cataaacagc cgttgctaaa gcttcgacta attcctctgt tgtttcgcct ttcagaccta
      301 agaattttgc gatatctgcg taatctgtat ctgcacggaa atagtcatat ttagggaaca
      361 tcgcatgttt ttgtggatct tttgcattat agcggataat atgcggtaaa agaatcgcat
      421 ttgtccgtcc atgagggatc ccgtattccc cgccgatttt atgtgcgact gagtgacaaa
      481 tacctaggaa tgcgttagca aacgccatac cagccattgt agaagcgttg tgcatttttt
      541 cacgtgattc catatcaggt gtttttactg atttttctaa atagtcaaag actaacttga
      601 ttgcttgtag gctcaatcca cgtgtataat ctgaagccat gactgaaaca taggattcga
      661 ttgcatgtgt taacacatcc atcccggtat ctgctgtgac agatgctgga actgacatga
      721 cgaattgagg atcgacgatt gcgacatctg gcgtcaatgc ataatctgct aacggatatt
      781 tcacatgtgt ttcactgtca gtgatgaccg caaatggcgt tacttcagaa ccagtccctg
      841 atgttgtcgg gatacatacg aattgtgttt tttctggttt gtcgatctta tatgtccgtt
      901 tacggatatc caagaatttt tgttttgcac caaagaaaga tgtgtctggg tgttcataga
      961 acatccacat tcccttagct gcgtccattg cagaaccgcc tccaagagcg attactgtat
     1021 ctggcttgaa gtctgccatc agtttcgttc ctgcgtatac ggtatttgtc gatgggttcg
     1081 gttcaacatc tgagaagact tcgatcttca catcattttt acgtcgtgcc aatacttcac
     1141 gaactgtatc gcagtaaccg aattggacca taccagggtc acaaacgatc atgacacgtt
     1201 caacgttttc cattttctct aagtacaata gagagttctt ttcaaagaag atttttggcg
     1261 gtaatttgaa ccattgcatg ttatttctcc gtttcgctac agttttgaca ttgattaagt
     1321 ttacagcaga gacgttacga gaaacagagt tcttaccata agaaccgcat cccaaagtca
     1381 atgacggaat catttcgtta tagatatcac cgatgccgcc ttctgcagat ggtgtattca
     1441 ctaaaatacg acaagctttc attcgaagac cgaatttgac atgcaactct tcgttttctg
     1501 aatggataac tgctgtatgt cctaatcctc caagattcaa cataccttca cacaaatcaa
     1561 acgcatggtc cgtgttgtta gctttgatca tggcaagaac tggagaaagt ttttctcttg
     1621 atagcggata atctgggcct acgccttcca attcagcaat cagcattttc gttccttttg
     1681 gtacactgat tcctgccaat tttgcgattt ccatcgcaga atgtccaacg attgatggat
     1741 tgaccgcata ttttccttcg ttcatcactg catcttctaa tttttgcaat tcatctggtt
     1801 ttacgatata aacttggtgt gcttggaatt ctgcttttac tgctgcatag atttctttat
     1861 ccacgatcac agcttgttca gaagcacaaa tcattccatt atcaaatgtt ttcgaaacga
     1921 tcaaatcgtt cactgcacgt ttaatttttg ctgttttttc aatataagct ggtacgttac
     1981 ctggacctac acctaaagct ggttttcctg tagagtaagc agacttgacc attccagctc
     2041 cacctgtcgc taagacgatc gcgatacctg gatggttcat tagcatagaa gtcgcttcga
     2101 tcgaaggatg ttcgatccat tggatacaat tttcaggagc tccggcagcg atagcagcat
     2161 cacgtaccac tcgtgctgct tctgcagaag atttttgggc acttggatgg aaagcaaaaa
     2221 cgattggatt tcttgttttc aacgcgatca ttgatttgaa aatcgttgtg gaagtcggat
     2281 tcgttgttgg agttactccg caaaccacac cgactggttc agcaatttca atcaaccctt
     2341 tttggacatc ttcattgatc acaccaactg ttttatcatg tttgatatta tgccaaatat
     2401 attcggacgc atacatattt ttgattgctt tatcttcgta aacaccgcgg cctgtttcct
     2461 ctacagccat cttcgctaat ggcatatgtt gatccaaagc tgccattgcc atttcatgca
     2521 cgatatggtc tactttttct tgatcaaagc tttccatttc tttcaatgct gcatttgctt
     2581 tttctgccaa atcatcaatc attgcttgta cgtcaattgt cttcgttttt tctttttcta
     2641 ttactttagc catcattatc ctcctaatgg gtcatggtta tttgttaaat aattcacatg
     2701 tatatcatac aatatttatt tttctatgta aacacttttt tgtgattttt ttcacagtta
     2761 tttttaaata taaaattgct ttatttacag gtgtttgtat agaaaaatat ataaagttat
     2821 ttattattat ttatatgaca cacccgatta ttcaatattg agcaatatat cccatgctct
     2881 tatctctttc ttttttgaat aaaaaatgag gtaggacatc tttctgccct acctcgtctt
     2941 taaataagct ttgatactta tttttcttcc ttctcttctg tctcttccag cgtttctgtt
     3001 gtttcagttt ttacttcaac tgtctcagct ggttcttctg ttgtttcaac agtagtcgtt
     3061 gcatcatttg ttacgacagt ccctggtttg accgttttga ttgctgcacg atcgtactca
     3121 aggaagatcc cttcgcagtc taaaacaact gtccgtttgt cattgtcgat ttctgaaaca
     3181 actccatgta atccgccgat cgttacgact gaatcacctg gtttcatgct atctaacaag
     3241 ttttgacgtt cttgctgttg tttcttttgc gaacgtgaca taaaaaacca cattgctaat
     3301 agcgcgataa acatcacaag cattggtaat gttcccattt ttttcacctc actaattctg
     3361 tatctacaaa aaacacttta gcagaaaaat gctgataaca ctagtttttt acttaatttt
     3421 taaaagattt tcctttagaa gctttttgcg ttttctttat tgaacccgta ttcttcaaaa
     3481 aaggcttctc taaattcaag caaattatca tccatgattg cttgacgtac ttgtttcatt
     3541 agattcaaca agaagtataa attgtggtaa gaagtcaaac gaatcccaaa tgtttcatca
     3601 catttgatca aatggcggat ataggcacgt gtatagtttt tacatgtata acaatcacat
     3661 ttctcatcaa ttggacggaa atcatgggca tatttcgcat ttttcactac tagacggcct
     3721 tgagaagtca tacatgtgcc atttcgagcg attcgagtag gcaagacaca gtcaaacatg
     3781 tctactccac ggataacacc atcgatcaat gaatcagcag caccgacacc catcaagtaa
     3841 cgtggtttgt tttcggggat caacggtgta gtgaattcta atacacgatt catttctgat
     3901 ttaggttccc cgacagataa cccgccgatt gagtaaccag ggaaatccat cccgactaga
     3961 tctttcgcgc tttgacgacg aagatcttca aaccctgctc cttggatgat tccaaataat
     4021 ccttgacggt ctggattagc atgagctttc aatcctcgtt ctgcccatcg agacgtacgt
     4081 tctactgatt ttttcacgta gtcgtaactt tcatcgaatg gtggacattc gtcaaaactc
     4141 atcatgatat cagagcccaa tttattttgg atgttgattg ctttttctgg tgataaaaac
     4201 atacgcgaac cgttcaagtg atttttgaaa tgcacgcctt cttcttcgat attccgcata
     4261 tcacttaatg aaaaaacttg aaagccgcct gaatctgtta aaatcggttg atcccagttc
     4321 ataaatttat gcagtccgcc agcttcttct actaagtctt caccagggcg tagccataaa
     4381 tgatatgtat tacttaaaat aacgccagca cccatttctt tcaactcttc tggggacatt
     4441 gtttttactg tagctaatgt tcctactggc atgaacattg gtgtggggaa agttccgtgt
     4501 ggcgtgatca attcccctaa acgcgcgcca gtatgttttt ctttcttgat taaacgatag
     4561 cgaatggcag gttgcgtcat tcatttccct actttctata taaaatatct tgacaactcc
     4621 caccatcata atcgtttcaa gtgctttttg caagttccct cggcttcctt ctactttatt
     4681 taatattctt ttttttatcc tttttttatg aataacaaaa aaaagaaaaa cattatgaca
     4741 gaaatatttt ttgatacatg gtatattggt gttattaaag aaaaggaggg aaaaatcatg
     4801 caatcttctg cagaattaaa acgccaagca aaagagagtc taaaaggacg ttggggacaa
     4861 gctgttttac taaatctaat ccctacattg attggtattg ctactattct tcttattatg
     4921 attcctatta tcttgtttgc caccaccata tatgatggat cagcgagcgt ctcagaagcg
     4981 acaacttcag gaggcggtag ttcaggaggc ggtggcggaa ttatttccag catcattagc
     5041 gctttgttca tgagcggtat ttcttggact tatcttgata ttttacgtgg acaaaaagat
     5101 cagatcgaac cattcaaaga tgcatttcgt ggattcaaag gtttgtttat cggcggagtg
     5161 atcagcttag ctgtgctgat ctcgatcttt acaacattat ggggtttgct attagttatt
     5221 cctggaatca ttaaaagcta ttcttattct caaagctatt ttatttacta cgatatcgtc
     5281 caagaaacag gacaaacacc taaagtactg gatacgatca ctgcaagtcg aaaattgatg
     5341 gatggttata aaggacaact tttctggtta gatctttcat ttatcggctg gcatatctta
     5401 gcattagcaa ctgctggtat tggttatcta tggctcagcc catacatttc tgcaacaaaa
     5461 gcagcatttt atgaacaatt gccaaaagat atttaaaaga gagtgtgact tgtgaccgag
     5521 ggggtggcag gagaacaccg tttatcgaga ggcagtaaaa gaaacattca gcccattagc
     5581 aaaaaggagg tgtgacaaca ttcatgtcac acctcctttt tgtatagttc cagtaaaaag
     5641 aaaatcaact tagaaacagt taatcattcc tcttcttctg cttccggtaa tcgatggaac
     5701 ttgatcagtt cattcaccgc gattggtacg atagataaaa tccctaccaa gaaccagtga
     5761 ttcaaactga tgtgtactag gccgaatagt tcttgcgtaa atggcagcaa agcaacagcc
     5821 gttgtaatag ctaatgccag taacgccatt tctaccaaag ctttattggt cgctaaattg
     5881 actttgaaga tcgattggct gctgcgtaca ttgaacacat gcagaatcga tgaataagct
     5941 aagatcaaga atgcaacagt ttgaccgaca tgctgacttg cgtctaccca tgggctgata
     6001 gtatcgacat aactacctaa ataataacca aacaaggtta cgatggtgaa gacccctgca
     6061 tttatggcaa ttttttgcaa taaacctcga gcaaagatcc cttcattttt cggaatgggt
     6121 ggctgatcca tgatgccgtg ttccgctggc tctcttccta aagcaaatcc tggaagtcca
     6181 tcagcaacta cattgacaaa cagtagttgc acagctgtaa atggtgctcc ccatcctaac
     6241 agcatcgcaa tcaaaacaat aaagatctcc gaaatattac agcttagcaa aaagttgata
     6301 gctttacgaa tattctgata aaccgaacgt ccttgactga cagcgtctac gatcgtcgca
     6361 aagttgtcat ccgtcaaaat catatctgcg gcactttgcg ccacatctgt tcctgtgatc
     6421 cccatggcac acccaacgtt acttgctttc aacgctggtg catcattcac accatcccca
     6481 gtcatcgcta cgactgcacc cgtacgttgc caagatttga cgatccggat cttgtcttct
     6541 ggcgttaccc gagcatagac agagagagct ttgacacgcg catctaattc ttcgtctgat
     6601 aattgatgca gttctgatcc tgaaagtgct tctgacggat cattcaagat acctaattct
     6661 ttcgctatgg cactggcagt caccacatga tctccagtga tcatgactgt tttgatgcca
     6721 gcctttttcg ctcgcttgat tgctccttta ctttctggac gtggtggatc gatcattccg
     6781 atcagaccaa tcaaacgtaa gtctttttcc agtgcttcag aagaaatatc ttgcggttct
     6841 tcgtcataag tagcataacc aacagcaatc actctcagtg cccgtttacc aaagcgatca
     6901 ttaacgatcg ccgcttgttc tacatcgcct gaactaaagc gcggagcaag aacatcgaat
     6961 gctcctttgg tgattgagat gtatttttcg cccatttggt gaactgttgt catcattttt
     7021 cgttcagaat caaaaggaag ctcgtttact cgtggatatt tttcttctaa ttctgccttt
     7081 gtatgataat tctcttcaac agcccttacg atggctactt ctgttggatt acctttgata
     7141 acaaggtcgt catcttcttg ctcgaccgtc acatctgtac atagtgcagc cattttcaat
     7201 atttccatcg cgctgttcgt cattgaatct tcgatattcg ttacttcatc ttctttgctc
     7261 catacccggc ggacgcgcat ttcattttgt gtcagcgttc ctgttttgtc tgagcagata
     7321 acattagcgg ttcctagcgt ttcaactgct ggcaactgtc ggatgatcgc atgtttcctc
     7381 gccatcttct gcacaccgta tgcaagtgtc aacgtaacaa taacagtcaa ggtttccggt
     7441 acagctgcaa cagccaagga aatcgaagtc atgaacatct caaggagtgg ttctccttgc
     7501 agttcaccaa tcacaaatac taaagccgca gccgctaaag cgatcatact gattcgtttg
     7561 cctagctgat tcaatcggac ctgtaaaggt gttttttgca tagtattttc gttcaaaaga
     7621 tccgcgatct tacccatttc tgtagccatg ccaatggcag tgacgatcgc tttcccacga
     7681 cctgcagcaa ccgtacatcc tttaaatacc atattaagtt ggtcacctaa tgactcatct
     7741 tcttcagcaa taaatgctgc atctttttca actgcttcac tttctccagt caacgccgat
     7801 tcttctacac gtaattgtga tgcttcgatc aaacgggcat cggcagaaat agcatcaccg
     7861 gactctaaaa caagaatatc acccactacc agttgctctg actcaacagt ggtcactttg
     7921 ccgtctcgta tgacagttgc cgtttgttta ttcatatctt gcaaggattc cagtgctttt
     7981 tctgcgtttc cttcttggac aatcgccaat accgagttga tcacaacgat agcgatgatc
     8041 agcagtcctt caaataaatc cccatgttct gtagcaaatg cggtataaaa ggaaatcacc
     8101 gctgctacaa gaaggatgat cgttgtaaaa tcggacaagc ttcgaaagaa ttttttgatc
     8161 atcgattctt tcggcgcctc atcgaattta ttcaatccct gcttttttcg ccgttcatcc
     8221 acttcttgtg aagacaaccc agtatctgga tctgcttctg ttaccttctt tacttcttct
     8281 attgtctgct tgtattcttc catcctattc ctcctttaaa atcttcgtac aaaaaaaggt
     8341 acttatttta ctataacatc ctttttttat ttacttcaaa taaagggctt atcgattatt
     8401 tgttaagaaa gcgtaaaatt taaagtgctt atatttgcaa acgctaccaa aggatgctat
     8461 tatatagatg taaggaagga ggataccatc aaatagacag aagaatttct cgatagaaca
     8521 gtgtaagcaa acaaagttgt tagaagtaca ggtttcaccc agacatgcgt gtagagtaca
     8581 aacctataaa tagtgaatgc gtatggatgt ttggatcacg aagtatccga aacaagaagt
     8641 aatgcgatac gtaacaattg aataacgtaa acgtctgaaa attgaatagg aacaagagat
     8701 gtttcaaatg ttgaagatgt aacgaaaaca aaatttttgt ttaacatgaa gaaattcaac
     8761 accgtgcttt gcatgtatga tggaaagtta caatcatttc tgtttatttg aatccttccg
     8821 aggtacaaga aagccgagct tatcgagagc tcggcttttt ctttgtcata aaatctttgt
     8881 aaagcttttt tgttattcaa aactagcggc ttttcataac cttatttcac gaacatcgca
     8941 tctccaaaac taaagaaacg atagcgctct tcaatcgcat gctggtaagc agataaagtc
     9001 aattctcttc ctgcaaaggc actaactaac atgactaaag tcgattttgg caaatggaaa
     9061 ttagttgaga aagcttctac cactttgaat tcatagccag gcgtaatgaa aatatcagtc
     9121 catccgctgt ctgctttgat ttctccatta aatttcgttc caatcgtttc taatgttcga
     9181 attgaagttg ttccgacagc cacgattttc ccgccatttt tacgtacttg gttcaatcgc
     9241 tcagccgctt cttccgtcaa acggtagaat tcactatgca tatggtgttc ttcaatttta
     9301 tctacgctga caggtcggaa tgtacctaac cctacatgta gtgtcagata gactaattca
     9361 acaccctttg cttcgatctc atcaagtaat tctttcgtaa aatgcaatcc agctgttggc
     9421 gctgcagcag aaccattttc tttcgcatag acagtttgat agcgatctgg gtcttccaga
     9481 cgttctttga tatatggagg caatggcatt tctcccaatg attcaagaat ctctagaaaa
     9541 attccttcat actcaaagtc aatgatccgt ccgccgtgtt ccaattcttc tttcactact
     9601 gcttgcaatc tgccatcacc aaaagagatt cttgtcccaa ctttggcacg tttcgcaggt
     9661 ttgatcaatg tctcccacgt atctccttgt gtattcgtta gaagaaggac ttctaaatgc
     9721 gcaccagtat ctggtttttc tccatataaa cgagcaggca gaactcgtgt attattcata
     9781 actagcgcat caccaggctg taactcttca atgatttcat ggaaatgttt atcttccatc
     9841 tctccagttt tccgatccaa aacaagtaaa cgagaatgat cgcggtcttt taatggtgtt
     9901 tgtgcgatta attcttccgg caagtcaaaa tcaaaatctt ctgttgttaa catatcgtca
     9961 ctcactttct atcatgtgct tcatcattct atcatgtttt tcgttctgtt ggcaaaatca
    10021 gcactttttc acttctattt tttgttttcc taaataaaaa aactacccta tttgtatttt
    10081 ttcattgttt taggcatact agtaatagat agttcttcat tgaaaataga aaaagaggtg
    10141 gcaccatgat tgaatttcaa aatgtgtcaa aaatttataa aggtggaaaa gtcgctgtag
    10201 aggacgtcaa tctttcattt gaaaagggtg agttcatttg ttttatcggt acgagcggaa
    10261 gcggaaaaac gacgacgatg cggatgatca accgaatgac tgatccaaca caagggaaaa
    10321 ttttgattga tggaaaatcc atccaagaaa ttgatccagt ggaattgcga cgtcagatcg
    10381 gctatgttat ccaaagtatt ggattgatgc ctcacatgac gatccgtgaa aatatcactc
    10441 ttgtccaaaa attgttgaaa gtcagtcaag aagaacggaa taaaacagct gaaaaaatga
    10501 ttgatcttgt ggaattgccc cgtgagatgt tagatcgcta cccacatgaa ttatctggtg
    10561 gtcagcagca gcgtattgga gtcgttcgtg cccttgcagc gaatcaagat atcatcttga
    10621 tggacgagcc attcggtgcg cttgatccaa tcactcgtga ttccttgcaa gaccttgtca
    10681 aagatttaca agagcgtttg ggaaaaacga tcgtatttgt aacccatgac atggatgaag
    10741 cgattaaact agcaagccgt atcgccatca tgagtgaagg ccgtgtgatc caatttgata
    10801 caccagaaaa tattttacgt catcctgcaa acgatttcgt agaagagttg attggagaag
    10861 atcgcctact acaagccaag ccaaatgcga caagagtcgg cgaagttatg ctaaatacag
    10921 caatcacgat tacaccggaa aaatcattac aagaagcaat caaactgatg agggaaaaac
    10981 gtgtagatac gttgttagtt accgataatt cgaatgtatt aaaaggattt atcgatgtag
    11041 aaacgttgaa taaaaaacga ggaaaagtat ccagtgtcgg cgacattttg aataaacatg
    11101 ttttttacgt aaaagaatcc gcctatcttc gtgatacctt gcaacgcatt ttaaaacgcg
    11161 ggctgaaata cgtgccggtc gttgatgaac agaacaaagt cgtaggtatc ctgactcgtg
    11221 catcattagt ggatatcgtc tacgatgtga tttggggaga agatcccgca actactgatg
    11281 ttgcagagtc agctactcct gaagaatcta aggaggtctg acctatgcag cagttttttc
    11341 atcagcacgg ttcagaaatt ctctcaaaag gttttgaaca tctttatatt tcaggacttg
    11401 ctttgatcat tggtatcatc attgctgtac cgcttggtgt cttactgaca cgttttccaa
    11461 aagctgccac gattgtgatt ggcttaacca gtgccttgca gacaatccct tctcttgctt
    11521 tattggcatt gatgatcccg ctatttggcg taggtaaatt acctgcgatt atcgcactct
    11581 ttatttattc attattgccg attttacgta atacgtacat tgggatgaaa aatgtcgatt
    11641 ggaattatcg ggatgtggca aaaggcatgg ggatgactga gttccaatcc attttttccg
    11701 ttgaattgcc cattgctatg ccaacgatca tggctggtat tcgtttagct gccgtttacg
    11761 tgattgcatg ggctacactt gcctcttata tcggcgctgg tggtttaggc gatttgattt
    11821 ttagtggact gaataattac caaccagatc tcattttggc aggtacgatc cctgtaacaa
    11881 ttttagcact attggctgat tggcttctag gtctcttgga acaccggctg acaccgatcg
    11941 cacttagaga ggagaatgaa gaatgaaacg tatactaaaa atgaccatgg ttcttttctc
    12001 tcttcttata cttgcgagtt gttccttccc tggtcttgcc agcaatacag atgaagacac
    12061 catttcgatc acaggtggaa tcacttcaga agcacagatc ttagcaagtc tagttgccgg
    12121 aatggttgaa cattatacag ataaaaatac cgcaatcatc aacaatctgg ctactacaac
    12181 tatcaaccat caagcgatga tgaacggaga tgcttcaatt tcagcggctc gctacacagg
    12241 aacagattta acgactacat tgaaccttcc tcctgaaaaa gatccgaaaa aagcgtttgc
    12301 taccgtgaaa gatgaatttg agaaaagata cggtcaaacg tggttcccgt cctatggttt
    12361 tgaaaatacg tatgtctttc ttgttcgaaa agacaccgca caaaaatacc atctatctaa
    12421 agtcagcgat ctgaaaaatg tagcggatga attagtagct ggtgtagata cttcttggat
    12481 caatcgtaaa ggagacggtt atgacggctt ccaagaaact tatggcttct ccttcaattc
    12541 gatattacct atgcagattg gacttgttta tgacgcagtc gaagcaggaa aaatggatat
    12601 tgttcttggc tactctacgg atggacggat cgccagttat gatctagtca tgttggaaga
    12661 tgatcgtcaa ttcttcccac catatgatgc tgctccagtt gtagacaaca agatattagc
    12721 tgatacgcct catttaaaag aagccttaaa taagttaggt cataccatca gtacggaaaa
    12781 aatgcaggaa ttgaactacg aagcagataa taatctagtg gaaccatcag tagtagcaca
    12841 acgtttctta caagaaaacc actattttga agggaagtga agcaattgga taaaatgaat
    12901 gtctttcaac aatttttcta ttatttccag gaaaatggct cctatatctt tgcacaattt
    12961 atccgtcact tcctgatttc tatctatggt gtcctctttg cagcagttgt cgggattccg
    13021 gttgggatca tgatttctag gagacgtaaa ttagcaaact gggtgattcg tttggcgaat
    13081 atcatccaga cgatcccttc tctagccatg atctccattt taatcattgg attaggcctg
    13141 ggagtcaatg tcgtgattgt tactgtattt ttgtattccc tcttaccgat catcaagaat
    13201 acgtataccg ggatgatcca agtagacaaa aacatccttg atgtcggcaa aggcatgggg
    13261 atgactgcta gacaacgact attcatggta gagttaccac tctctgtttc tgttatcatg
    13321 gcaggcataa gaaacgcgtt agttgttgcc atcgggataa ccgcgatcgg tgcattcgtc
    13381 ggtgctggtg gtcttggaga tatcattatc cgaggaacca atgcaacaga gggcacatcg
    13441 attattttag caggtgcatt gccaactgca ttaatggcga tcatcacgga ctggctttta
    13501 ggtattttgg aaagacggct agatccagcc agccgtacat cacgctgatg ttattgtaaa
    13561 aaacaaaagc ttctgcgacc atttgttggt cgcaaaggct tttttagttc tgtcattttt
    13621 aaggcaataa tccactctga ttcttccctc cttatgggca aagagttgct tttcttagct
    13681 atttatccat tccgtatact ccaacttcat actgccaacg ggttcatatc tgcatccacc
    13741 gactaagttt ttttcttatc cgctaaggca ttttgccaat ccattttccc atcactcgtc
    13801 atggaattca taccacatga tctctaaata ctcgtctgct tgttctttga attgggcatc
    13861 aattcttaca tcctttggcg tggctttcat ttaagccttt tccatcagtc ctcgattgtt
    13921 cgatgccttc agctgcatca tcaaaactgg tgactgccgt atcggtaact tcgatcatct
    13981 tttatacaat cgggaacttg ccatcctcat ccttggctaa aaacatatct agccattcca
    14041 gcttctcgcc atgggaggtt tgcggttcct aaaaccggta cacgattctt atggactgca
    14101 tccgtcgcaa ctagacttgg cgatacgatg atccttcacc agaagagcac ccccgtaaac
    14161 caattgatcg atatattgcc aataagaaaa gacattggcg taaaagatat cgatccctcg
    14221 tgatgcattg ccgttgatac tgctattcat ggccgaaagc gccacgactt taacttcttc
    14281 cgtttgagtg acattcatgt tcggcaatgt cgctttggat acccgctctg ctaaaggaac
    14341 gacactggta ttgtatttcg tatctgtatc ttttccaaaa gaccatgcca acgaatcctc
    14401 tgggaaccaa taagacgact ccggttgatt gtccattgct tttttcaaca tacttttggc
    14461 tgtttctcga taaacgacat ttccaattgt cttcgcctca ctttggcgat aatcgatggt
    14521 cgttgccact gccaacacta acaacgatgc tccaatttta ctgattttcc ttgtcacact
    14581 tcttcctcct tgttttacat aaacccgtca acattccatt cctaaactca aacaatgacc
    14641 cttcaaaggt ggagatatag gaacaaatta aagaaatcat gcaataaatc caagaaggtt
    14701 ggttttagaa caaaaaaaga gtctcctttt tggggagact ctttgttaac tatctaaaaa
    14761 ggttggctct tctcacttca ctcataatgt gtccaggcag aataaatttc tacaacttta
    14821 ttttcctcat caactttgta aaccactcga tgctgtctat tcagcctgcg tgagtatctg
    14881 ccttcatgtg taggtctcag cttttcaaaa gactgcgtgg gcatatatgg atcttccttc
    14941 aatgtctgaa tcacttcttc aaattgtttc tttaaattcg tttgcttgat ttttcttaaa
    15001 tccactttcg cagagttttt gattgcgact gtatagttac tcatcaaaga gcttcccaat
    15061 caatatcatc gatattcgta aagctactgt cgtctttttc gcggtctcgt actttatcta
    15121 aagtacctgt ttgctcaaga aaaagggttt cttgaatcgc tctccagtct tccagcccaa
    15181 tcaatacagc attgtttcca ctacgatcac taataatctc gatttcagta tgattttcat
    15241 ttacctcttt caataactga taaaaatttt tacgagcagt gctaggattc atcgttgtat
    15301 tagccattgt ctctcctcct ttttctgata taattatagc gtacttgatt aagtacgtca
    15361 aaaaaataca ataaagcact taaattcagc aaacttttcc tcttttttac atagagaaaa
    15421 agaccccttt ttagggagga tctttgtcca cgctcacttc ttactccttt acgactagcg
    15481 gtagccaaac gtaaagtaat tggtaacaac gtatcatctt tagcaaaggt cgaatccaaa
    15541 gcctgtgagt ctatgcaaca acaccaatac acgaaggttc ctcgttgcag tgtgacttga
    15601 ttgatatctt gaataacctg aggatacgca cgaaagattt gtaacggtta ttcaaaactg
    15661 attttggccg tcaagtcttc tactgcctca aaaatgattg cctctttcgt ctcctgtcat
    15721 tcatgttcac tatcgatttg atacttgctt agaccgttgg gtttgtgaat caccaattaa
    15781 aaatggcact gagttatggt aacaaaaaat ggtcacttga cgaggctgag attcctactt
    15841 atgaagacac atggcactta agagtcgagg taaaggaaga agctgaaaat ataggaggct
    15901 gtacattatt tggcaaagga ttcggaaatt atgatcaaga catcaaaatc aaaatgtttt
    15961 acagctaaat aggaagaata ataacatttc atacgctgtt cccatcttta atggcttata
    16021 gagggcacct ttagctgaga ataagacaaa acagaccctc tagcttcaat taagagctag
    16081 agggtctgtt tttgatttta aaacttggtt tatttcttca aatggtagct ataggtgctg
    16141 acaacgatat tttcacgcca agacaatcgc aatcttaacc gcaaacttgt ttggttatgg
    16201 agaatattct gccagcgtct gtttggtaca aattgaggaa tcaacacagt agttgtatag
    16261 ttttgtttcg ctgcattttt acttacgata tctacataac ggataattgg attttcaatc
    16321 gagcgataag aagagtggac gattgaaaaa cggacatctg ggaaatgctt tttaaattct
    16381 gcttcgattt ctttttcttt ttcgacatct tcgtctagcg aaacatgcat cgcaacgaca
    16441 taatcaccga tcgaacgtgc gtaattcaac gcaccgatat ttacccgtgt cacattcccg
    16501 actaatacaa gaacggtatt cccgtcataa tcatgtagtt ttgcatcatt ttctaaacga
    16561 agctgttctg ctactttttt ataatgatca tggatcttat aaaaaatgaa cataacgatt
    16621 ggcataatga tgaagaaagg ccaaatgtcc cctaaccgat agacaaacaa aatcgcaatg
    16681 attgcatatg agatgaacgc acccgtaata ttggcaatcg atttgcttaa ccatcttttt
    16741 ccttcttttt tccatttgac gaccatccct gtttgagata aagcaaatgg aatgaacacg
    16801 ccgatagagt ataacggaat caagcgttct gttgagccat ggaaaataaa cagcaatacg
    16861 atcgaaccta gcgctagtgt gataatccca ttggaatagc ctagtcgatc cccacgatct
    16921 tgatacatgt gaggcatgaa tttatctttt gccagattgt atgcaagaac tggaaaagca
    16981 gaaaaaccgg tgttagcagc aactgctaaa atcagcgctg tagcaaattg aaggacgtaa
    17041 tacaaaatac catgtccaaa gacagcttta ccaatttgag acaaaacagt gacttctttt
    17101 tcaggaacga tcccatacca atagttgata aatgtgatcc ccacgaagaa gaaacctaag
    17161 atcaatgcca tcatcgtcaa tgtagcagcg gcattttttg ctcttggctt cttaaagaat
    17221 ggtacagcat tactaatcgc ctccacccca gttaaagagg aagaaccaga agaaaatgct
    17281 cgtaaaatca aagcgataga aacacccggc acagccgctc ctggaagtgc agtagcttgc
    17341 aatggcacag cacctgtcac gatattatat aaaccaacaa cgatcagtaa cgagatcaca
    17401 aggataaatg tgtacaccgg aaataatagg aacgatgcag attccctcag cccacgaaga
    17461 ttcagcatca tcagtagcaa aacgattgtc acagaaatag cgacttgatg accgtagagt
    17521 gctggcaccg ctgatgtgat cgcttcagca cctgctgaga cagatactgc tactgtcaac
    17581 atgtagtcga tcaataaaga gccaccggaa atcaagccag cattctttcc aagattctca
    17641 ctgctgacga catatgctcc cccgccatga ggataagcat ggatgatttg acgatatgat
    17701 agcgttaatg aaatcaataa aataataaca aaagcggcaa tgggtagcga ataccagatg
    17761 gctgcagcag acaaagcgac taaaacgaca acgatttgtt ccgtaccata tgcaatagat
    17821 gataacgcat cagacgacaa taatgccaaa gcagcaaatc gggttaattt gtgctcatca
    17881 ttttcagcag attttaaagg cttacctact aacaaccttt ttaagtaatc caatttctaa
    17941 actcctttac acacaatttt acttcaagtt ttatagtcga aaatttatag taaacaagat
    18001 gttatagtac gctcactgac cttaaaagtc aataaacttt aagaaaataa ttggaaaaaa
    18061 acagaaaaat atcaagcgct ttttcaaacg ctttaataca gcaaaaatct aacatttttt
    18121 tatgggcttt ttctttgaat tctataataa aaggatagaa cttgacttag aaaatcaagt
    18181 tctatccttt ttgatatctt aacttttgga agagagatgt aaggctgctt tctacccatc
    18241 attcttacta ctcgaagcat agcgcagttg tcacaacctc ttgataaacg gtgtttaaaa
    18301 gcttgcatct gcggtaataa gctcaaccaa attaaaaaca taagaagctg tttttatttg
    18361 gtcgttctta ttacttgatg cagagcagct tttttacaac ctcttggtac acggtgttca
    18421 atcagctgac cctcggtatt agctcaaaaa aacggcaaaa tatgaggaac tatttttcca
    18481 tttttttctc taatactcag gtcaaaacac tgatttcaca acctcttttt ttaatgaaaa
    18541 atatggctct catgcgccgc ttctttgaat ttcgtcattt tttcttcgat gaacggatag
    18601 attgccgttc ctacgattcc aaagacaaca aacaaaccga tcatgatcca gattgctttc
    18661 gtagcatttg gccaataaat tcctcctgca gattcccgta acaagtttac cgcatgagta
    18721 aatggcaaga acggattgat catttggaag aatttccctg agacttggat cggatagttc
    18781 ccgcctccgc cagagatcga cagtactaag atgataatag cgatcccttt accgacatta
    18841 tcgaataatg cagccaagac atagacgatc atcatgaacg ctaaggcgat caagacagca
    18901 aatgacacgc tgtagaccgg attttggaca tctactccta gtaagaaaat attccctaat
    18961 gtaacgatca agctttgcgc aatcgccatt gtcaaaaatg tcagcatacg agcaacgaat
    19021 tgttctcgtt tcgtaaaatt gtttcggtct ttctttccta aatagtattc tgtcgtagca
    19081 acacttgaaa gaagaacagc gccgacccac agacatagtg cagtataaaa cggggtgcta
    19141 gctgaaccgt tatttgcgat tggataaagc gcattggttt gtagctcaac aggttgtgta
    19201 aagaagtcac tttcttttgt tgcgtctagt ttcaataatt tgatgacttc gcctagatcg
    19261 acttcttgtt cgccttttcg gatcgcgtct gctgcttttt ggataccagc tttgatattt
    19321 ggccagtcat tgttgatcaa gtccgcagca gcgttcacag ctgtttcgac ttctggcatt
    19381 ttttcattta ctgttgtcaa tgtaccggtg atttcatttt ttagtgctgg ccaatcattt
    19441 tggataaaat cagcggccaa tcctaatttt tgctgaatga tcggtaattc attgttgtat
    19501 aggtctgccc cttcattgat gccattgacg atggtatcca tatttccatt cagcattgta
    19561 ttggcatcat ggatttcttg tccaattgca ggcatttctt tttgatattt ttctaaaatt
    19621 gccactgcat tcgttacagt tgctttcgtt gagctgagaa gcgaatcaaa gtcgatctgg
    19681 tccgctttgc tcagtgcgcc ttgtgcagtc ccaatcgtat cgatgacttg gtctagtaga
    19741 gaagtgacag tggaactgat ttgacctgta ttgataccag caatgatgcc attgatatta
    19801 ttaacaacgg catcaatttg atctagcaat tcatcaatag ccttcgtgtc ttcattttga
    19861 acagctgtgt tcaaagcaga taggcggttt tgcagattgc ttagcaaggg ttttaattga
    19921 tttagctgat caataattgg ctgtaatttc gtatttccag cacttgtttg caatttagtc
    19981 aggaactcga ccagtttatc gattgcattt tgttgttgag atattccgtc aataaagccg
    20041 ttcaatacat tgctgatgtt tttcttttca tcatcagtca gcttaccatc ttcaatagct
    20101 gttcttacag tatctattaa cgaacctgtc gttgttgcca cttgtccaat tgacttcaat
    20161 gtaacatcta cactgtttgt gatgcttggt atcgcatctt tcagctgaga ggcacctgat
    20221 tttgtttggt ttgctagatc acttgcctga ttttctaaat ttttcacatc tggcaagata
    20281 tcttgtactt gttggatgat cgtcaagcct tgttttgctt catcgattcc ttggttcatt
    20341 gtctcttgga tcgaagcaaa atcgccgtcg atctctgcta gttgcttacc ggcattttgg
    20401 atctctggga ttttttcttg caaatcaagg atgatttttg cttgatcttt caactcaggc
    20461 attttgtcat tcaatgcaac gactttttca cccatctcat ctactttagg gatgtaatcc
    20521 acgaattcat ttgctttatt cagtttttcc ttgatttcag gtagttgact ttgtaattcg
    20581 aggacttgtt ttgtgtagcc gtcgatcgtg tccaaatttt catctgttga taaaatcata
    20641 tctttaactt tattgatact tactaggttc gtatcgatgt cgtaacctat ctcattgaat
    20701 actttcaata aagtcgaact ggctgttttg ataaattcat ttgtgatttg cgattggatc
    20761 gaacttgctc ctttatcggt gattttcggt gcaatcgcat tgattttttc atttaccgta
    20821 tattcgattt ttggtttctt gatatcacca ctagtaaaac tcagcagatc ttctgagaaa
    20881 tcctttggca agtaaatacc tgcgtaatac tttccggaac ggactccgtc ttctaattgt
    20941 tcttttgaat caacgaattg ccatcctaat tgtttatttt tatgaagcga ttcgatgact
    21001 tgctccccaa tggccacttc tttaccttga aactctgctg gcttgtctgc actgtaaaca
    21061 gcaattggca gctctccagt atttccatat ggatcccata atgctttgat gttaaaccac
    21121 gcatatagcg aagggatgat catgatcgcg atgatcagaa gtgttgcaat cgggtttttg
    21181 aaaatccgtt tccagtcaag caaatataat cgaagcgtat ttttgattga ctgcatagtt
    21241 ctcccccttc ttcttttttc agctgaatta ctttaccatg tatttcatac ttttttcaat
    21301 cggctttttt caaaaaagtc gaatttttgg acatatcacg gcaattgtct cattgtaatc
    21361 tcttacatat tgagaaataa ttaaggatta cagcctttac tttatcatga aataaaaggg
    21421 aaagataatt ttatgccaaa gtttttatct attatacgta tacgcaaaaa agctaaaaca
    21481 ttttttgtct ttgcccctac aaaaatgttt cagctttttt cgttttttat tcctgtattt
    21541 cttatttttc gaatgacagg atgattttcc cagcaggagg atgtccttca actagctgat
    21601 gtgcttggat gacatgctta agtgaagcag acagattcat tgaaataaaa acatgaaagg
    21661 ctcctttttg gtaggctttg attatgccag caaaggcttc tgcatctaga tattcctttc
    21721 ttggaacaaa cgattcataa aagccttcct ttttttgccg caaatctaga tctgggaggt
    21781 catttaatgc aacatacctg ccgcctggtt tcatgatctg gatgccggtt tctcctttga
    21841 tacttccttt cgtcgcatcg attacaaggt ctgcctgatc agcaaattgc agacctggat
    21901 ttgttttatc ataagcagca aatgctgaag ctcctaattt ttttaccttt tcctcatttt
    21961 tactggatgc actggttaag attcggattc ccttttcatg gagaagctgg atcagacttg
    22021 acccgaccgc acctgatgct cctagtatca ttacagtatc tgtcggctgg atttccgtca
    22081 aatggttgat tagattataa gccgtaattc ctggcgtgac cattccggct gcttcttccc
    22141 aactcatttt atctggaatt tttgctactt ttgctgatgg caacacgact tcttctccgt
    22201 aagtcccgcc gactgcatgg acagctactc gatcacctac atgaacagtt gtgacatctg
    22261 aaccaatctc tgtcacaata ccagcgccat cattacctgg tacataaggg aatttcaatg
    22321 ttcgtatctc tttcatttct cctaaacgca aggcaacatc ataaggattc acactgaatg
    22381 cttttatttc tacacgaaca tgtccagaac cgacttctct gggatgagca tcgatttctt
    22441 caaaaacatc ttgtgcttct ccgtaaccgt taattgcaaa tcttcgcatg gtcaccatct
    22501 ccctttttct ttaagtttac gtttatgtct ttattttgac aaaaaaaatg tcttttcgtt
    22561 ttggcgcatg attcaaaaca aaatagttgt cttttttcgc gtaacgtgtt aaattattta
    22621 tctaaaagcg taaagattac gatttacgct aataaaaaat aattggagga atttgttgat
    22681 ggctaaaaaa tcaaagattg ccaaagcaaa aaaacagcaa gaaacgattg aacgctatgc
    22741 tgctttacgc caggaattaa aagcgcaaaa agattacgaa ggcttgcgta aacttccttt
    22801 agatgctcgt ccagaacgat tgaaaaatcg tgatttaatc gatggacgcc ctcgcggata
    22861 catgcgtaaa ttcgggatgt cccgtataaa attccgtgaa ttagcacata aaggtttgat
    22921 tccaggagta aaaaaagcca gctggtaatc caagtctggc tgtaatgtaa aggaggaggg
    22981 cgcatggacc actccttgga tcatcaaaaa agatacgttc gcttcttcta gcagaaatgc
    23041 tggtactaga agcagacgta tcttttttta cgcacagctg gtcctttttt atatgtaaag
    23101 gctgcatggt tacttcgcta tatttattta gtaacaggag tcagtgcttc gatacccaca
    23161 ctaattttca atgctcggtc aacttctgcc ataatgggtc gatccaaatg gcagaccttt
    23221 tctttcaatc ttgatttatc gatcgttctg atctgctcca acaggataac ggagtctctt
    23281 tctattcctg ttccagtagc tttgatccca atgtgagtcg gaagcttagg tttagccatt
    23341 tttgccgtta tggccgcaac aatgatcgtc gggctaaaat ggttacctag attattttga
    23401 ataaccaaaa ctgggcgtgt tccgccttgc tccgatccca cgactggaga aagatcagca
    23461 aaataaatat ctcctctttt taccatagga tcctccttat tcttgatatt ctcttggtat
    23521 ccgctgtcct aatccgcaag ccacttcata gtggatcgta cctaattgat ctgctatatc
    23581 ctgcatagtg atttctttgt ctgcattttt gccgataagc gtcacttttg ttccgacagg
    23641 aaattcttga ggcaatcgga tcatcagttg atccatacat acacgcccaa tcgtttcaca
    23701 gtagttccct tctaccaata gagaaaaacc ctgcatcttt cgtggccagc catctgcata
    23761 accgatcggt atcgttccga tccactctgc ttcaggagtg atatatgttt ctccatagcc
    23821 gattccttca cctgctggga gttttttgac ttgaatcaat tcagaaacca gctcaagtgc
    23881 tggctgcaat ggataaactt ccggtagtgc gtgcccagag ggattaagtc cgtacattgc
    23941 tactccataa cgaatcatat tgccgattgt ttcatcatgc cataaagccg ttgcactatt
    24001 gctgacatgt acatatcgag gaagttcggg aagttttttc agcacttcta taaagcgttc
    24061 tttttgcaga ttccaatatg tatcatctgc ctgatctgct gtagaaaaat gggtaaataa
    24121 accttcccat tctaatacac gactttcttt gatgaatgca gctgcctctt ttacttcttc
    24181 aggtgtacaa aatccgatac gacccatccc agtgtctgct tttagatgaa tcgaaagagg
    24241 cgtctctagc ttacttttct ctaaaacagc agctgctgct tgcaaccatt cccgtgtacc
    24301 tgcagttact gataaatcat gagcaacagc tacagtcagt gcgtcgtaag gaaccatatt
    24361 caagataagg atgggctgag taaatccagc ttctctcaac tcgactcctt catctaaatt
    24421 tgaaacacaa aagcccgaag ctccacctgc aactgctgcc tcagctgttt caatagctcc
    24481 atgaccgtat ccgttcgctt ttactactgc aaacaattct tttccttgcg gaagtcttgc
    24541 aacttcattt gctacatttt cagttatagc ttttttatgt atcactgctt tcgttgggcg
    24601 gtgccaagcg acaaccatcg tttttccttc tttctagtct tccaaaataa tttgtgcaaa
    24661 agctgtttca tttgtatgag taatactgac ccatacattg ccttcatgag gtgaacgcgt
    24721 cacaacaggc tgaccatttt cattttttaa aatctcgaca tcttgaaagg taacttttcc
    24781 gatcccagtt ccccaagctt tagagaaagc ctctttgcaa gcgtaacgcc cgcctaaaaa
    24841 ttctacttgg cgatgaaaag gcaaggactg gaatagtttc atttcatcag aggtcaagat
    24901 tcgtgcaatg aattttggtt tttcttcgat cagccgagtg atcctaggaa gttcgactgc
    24961 atcgatccca attcctttta tcatatgctt ttctcttttc aataaattta gaacactctc
    25021 attctaccaa attataacca ttttgccaca aataagtcca caaataacaa aaatgaaagt
    25081 ttctcttaaa aaagagaaac tttcatttta tgtttaatcg ttatttgaac ggattacaaa
    25141 tccgcgtttt ttatcattgt gacgtttacc gccatctttt tggctgttat tatttttgct
    25201 ataaccgcct tttgatttgt ttccacgata attaccgccg tcacgacgat tacggttgtt
    25261 tccgccacca cgtttgccat ttttattgta tccttttttc tgcattggca atgggcgttc
    25321 tggtgtgatc ttcactggca ctgcatcagc tggatctttt gctgtcgttt ttagcaaaag
    25381 tgcaactaaa tcttgtgcag aatattcttc taataattta tctgctgttt gcaggtattt
    25441 atctagacca ttttctgcaa gttttgtttc gatttgttca actgcagcac ctaattgacc
    25501 tttgaatgct tctttttcgg ttggtggacg taaagtcgtc atccgttttt tcgtcaagtt
    25561 ttcaatcaca tgcaagtagt ccatttcatt tggtgtaacg aaagtcacag acataccgcc
    25621 ttttccggca cggcctgtac gtccgatacg gtgaacgtag ctttctggat cttgagggat
    25681 atcatagttg tacacatgag tgacacctga aatatctaat ccacgtgcag caacgtctgt
    25741 cgctacaagg atatctaaat gaccgctctt aaatgaacgc aatacgctca ttcgtttttg
    25801 ttgagacaaa tcgccatgga ttccttctgc acggtaaccg cgtgcttcta atccgcgtgc
    25861 caattcgtct acacggcgtt ttgtacgtcc gaagacgatt gttaattcag gtgtttgaac
    25921 atcaaacaag cgagtcatga tatcgaattt ttcgtattct tttgcgcgga catagtattg
    25981 atcgatcaag tcagctgtca tttctttcgc tttgatcttc acatgatgtg gatttttcat
    26041 gaatttaacg ccaatattct tgatagctgg cggcatcgtt gctgagaaaa gtaatgtttg
    26101 tctttgatca ggaacttgtg aaatgatttt ttcgatatct tccaagaagc ccatattcaa
    26161 catttcatct gcttcatcca aaactaatgt ttgaacggtt ccaagtttca atgtgtggcg
    26221 gttaatgtgg tcaagcatac gtcctggtgt acccacaacg atatgtggac gatctttcaa
    26281 gccacggatc tgacggccaa tatctgctcc gccgtaaacg gcttgtacac gtactttttt
    26341 gtcgcgccct aaacgatata attcttcttg tgtttggata gctaattcac gtgttggtgc
    26401 gataactaaa ccttgtaatt cgtgacgatc tggatcgatt ttttctaaca ttggtaatcc
    26461 aaatgcagct gttttccctg tacctgtctg tgcttgtcca ataacgtctt ttccagctaa
    26521 tgctagtgga atcgtttctg cttggatagg cgttgcttct tcaaaaccag cgcgttcgac
    26581 tgatttcaac aattctggtg ataattctag ttctttaaat ttcaaatgaa tcctcctata
    26641 tggttgttaa ctgaggatgt agcttttttg ctaccccgtc gatttgttcg gtcaaagtgt
    26701 attgtttctt tttgacagtg gccacgcacg tttttatcca ttcttagccc ctgtggcacc
    26761 accgaaaaat cactttgcga agtttaggca ttagaaaagc caaacgggtc gcgttcagct
    26821 ttatcattat tatgacatct ggcttcaaca agttgtttct atggcaaaac cagtccaatt
    26881 tctcttcatc tttcggcaat aggttattct aacatagttt ttcgttttct gcaagtttac
    26941 agatttttat ttcatttgct gaagttgttc taccacttca aataagccca tgctgttgct
    27001 gccttttagc ataatactat ctgttgctgc aagattttgt ttgatagcat caatcaattt
    27061 attcttttct ttttcaaaat agaacacagg tagttggggg tatttttggt tcaattcttc
    27121 ttttagtgca tgcatttgtt ccccataaag gaaaatcatg gcgaatttct caggatcgat
    27181 atgttcactc atttgcgcat gcatatttaa agactctttc cctaattcca gcatatctgc
    27241 taacacagcg attctgcgtc cttttgttgg cagattttta aaagtatcta ataccagtcc
    27301 catggctgtt ggatttgcat tgtagacatc gctcaaaata gctgcaccat ttcctgccgt
    27361 tagccattcg gttctgtttt gagtgataga aacatgggcg agcccttggc gtatctcagg
    27421 tatggacagt ccaaagaagc gcccgatcgt atacgcaatc aaagcattcg ttacattata
    27481 acttccaggc agcgggatcg taaatgtttc tccttctact acaaaatcgg tttgtgcttt
    27541 tccttttgct gtcacttccg catgaacatc gccatttcca ataccgaatg ttgtgactgt
    27601 ttgtactaat gttgccgtta aaggtgtcag caacggttca tctgcgggca caacgagtaa
    27661 tccgtctgat acaagtccgt cagtgatttc cattttggct ttagcgattc cttctcgcga
    27721 cccaagattt tctatgtgtg cttcaccgat cattgtgatt gctgcagctt ttggttgagc
    27781 cataagtgaa agttccgtga tttcattggc gtgatccatg cccatttcca aaacgatctt
    27841 ttctgtatct tggggcatgt gcaaaatcgt gtaaggaaga ccaatattat tgttgtaatt
    27901 tccttgcgtc ttatatgttt tgtatttttc agacaagaca gacgcggtta gatctttcgt
    27961 ggtggtttta ccattgcttc ctgtaattgc aacgacttct gcgcctactt tttccaagta
    28021 ataggttgcc aattgctgca tggctttcaa aggatctgct acaggaataa ctggaaaatt
    28081 ttttggagct tgttcaacag gcaagctcca aaatgaagca gatgctccgt ttgtgatcgc
    28141 ttgctggata aattcatgtc catctcgcgt accagcaaga ggaacgaata aacttccttc
    28201 ggttatcttc cggctgtcaa attcgacatt ggtaatcttt gtcagtgcag agcattcgct
    28261 gcccacggct tgtgcaattt cttgtattgt tagattcatt gagatctctc ctaaaaaagg
    28321 ttgtgaaaaa agcgtttggc ctaaacggcg ggttcgcatg actctcactt ccaagtaaat
    28381 ttctctattc gtatttagaa gctagaatga acgcggttac gcaatcactc cagcctcttc
    28441 tttatttctc tttattcatt tttttcaaaa aaagattgac gctgatggta tcgattcatt
    28501 cctaactgga tcagttcttc aatcaaatca ccgtatttca agcccatatt ttcccataag
    28561 agtgggtaca tactgaactc cgtaaatcct ggcatagagt ttaattcatt caggaataat
    28621 tcatttttat ttgtcaaaaa gaaatcgcac cggctcaatc cgcttccacc taacatcgtg
    28681 taagctaact tcgcgtactc ttgcgctttt tgataaactt cttctggcac ttcggctgga
    28741 atctgcattt cgattttatt attgatatat tttgcttcat aatcatagaa tgctacgtct
    28801 tttacgactt caccaggcaa agtcgtccga acgtcttcat ttcctaatac agcaacttcg
    28861 atttcgcgcg cttcaattcc ttgttcaacg attgctcgag aatcatactg ataggctgtt
    28921 gctaaagcat tttgcagctc ttctcggttt tctgcttttg taatgccgac actagaaccc
    28981 atattcgccg gtttgacaaa catcggataa agcaaagaac cttcacattg atcaaatact
    29041 tttttaggat tttctttcca ttgattctta agtactggta cataaggaac ttgcggcaca
    29101 ccagcagctt gtaaaatata cttggtcatg attttatcca tggcacatgc actggtcaat
    29161 acgcctgcgc cgacataagg catattcaat gtctctaaga agccttggat cgttccatct
    29221 tccccgtttg gcccatgtaa aactggaaaa acgatggctc cttcttcttt gatttcgccc
    29281 ggattgatca cttttcctgt aaagccttcc tctgtctgtc cacttgggtc ccatgaaaga
    29341 tgcaagacat ctttgctggc aggtttttct gttagtaatg gacctttgac ccattgtcct
    29401 tcttttgtaa taaatacgag ttgaacttgg taataattat aataaatggc atttaaaact
    29461 gaaaatgcgg aaagaatgga cacttcatgc tctgcgctgc gtccgccata tagtaaagta
    29521 atcttcaaaa gattgtcctc ctgtattcta aatcgttcag tgatttactc tcatatttta
    29581 gcacaaaaca aaaataaacg aataacttat ttataaaaaa acgagccagc ttctaaaaga
    29641 acgagcgtca tttatttttt gtcagctaga ttatttgtcc cgttttttat aaaaagttat
    29701 gataaagaaa aggagggatg atgatggcgc aaacaaatcc acgcagccgc ttggcagaaa
    29761 tcattcgagt gttcatcaat tacaatgtag tgccaaactt tgtacagcaa aaaaatcccg
    29821 aacaggtaaa aaaagccttt gaagaactag gccccacctt catcaagata ggacagatgc
    29881 tttctgttcg agaagatttg ctttcttctg ccttcactca aacattcaaa acattacaag
    29941 atagtgtacc tagcgacaca ttttcaacgg tcaaaaagac gatcgaaaca gaactttctc
    30001 tttcattatc agatatattc gatgattttt caaaatcgcc ttttgcctct gcttctatgg
    30061 ggcaggctca tcgtgccaag ctgaagaacg gtgacgcggt agtcgttaag atccaacacc
    30121 ctaacatcgc cgaagagatc cgacttgatc ttcaactatt tgaacgagcg atccctttga
    30181 tcaaatacat tcctgaaact agcgtagttg atctaaaagg ggtactccaa gaagtaaaac
    30241 gttccttgat caatgaaatg gacttcttaa aagaaagtca aaatggcgaa caattctatc
    30301 aaaagaacaa tggctggaaa gagatccgca gccccaagat ttatgacgct ttttgttcga
    30361 aaaaagtgat cgtgatggaa gaaatgtctg gtaaaaactt gaatcattta atgaacgccg
    30421 aaaacaaaac tgaaactttt atcactggaa ttcaaaacaa gcagctgaaa caagaagttg
    30481 caaagctttt agttgagaac tttatgaaac aggtgtttga tgatggtttt ttccatgctg
    30541 atcctcatcc agggaatctg ctattccatg tactaacaaa agaagaacag acacaagcta
    30601 gccgaaaaac tgaaacagtc catgaaaaag agttcggttc ctttgctttt cgagcctcca
    30661 cttctgcaga agaccctgtt gcgccatata ccatcaacta catcgatttt ggtatgatgg
    30721 ggcatctttc tgcaggactt aggcaaaaac tcacacaagc cgttttagcg ctgtatacga
    30781 aagatgctta tcgaatcgaa aaagcggtcc ttcgactttg tcagcaagaa ggctcgtttg
    30841 atgaaagtcg gttccaccaa gaactgacaa gttttcttga acagtattat gattctccta
    30901 ttgatgaaat caacttgcaa gaagtattca cacatgtcgt gacgatttgt catcaaaata
    30961 atctgcagtt cgatcgtgat atcacgcttt tgctgaaagc atttgggaca ttagaagggg
    31021 tgatccgcgt cctcgatcct gaagtttccc tcatggaagt cgcttcgcct tttgctcaac
    31081 attattttct cactcatctg gatgtagaag atacattgaa acaaagcgga ttagacttat
    31141 tggaagggat gaaggctgcg cctaagatcc ctcaacagct ccaccatcta ttagaaatgt
    31201 ggacttcggg acaaggaaaa gtcaatttgg aattgaaaaa gcaagacaaa ttattgagca
    31261 ggatcgaaag tatgatcaat cggcttgttt tcggtatgat tttagctgca ttgatcgtag
    31321 ggtcctccct gcttgtccaa gcagcacctg tagaaaacgc agaggtcgtt tccttattag
    31381 ggatatttac gtatgctatt gccgcattcg tcattatttt tttggcaatc gatgcattga
    31441 tccaaatgta taagaagagg aaaaagtaga aaaaggttgt gacagaaaga atcagcttca
    31501 agaaataaga aggggtttta cataaattgt ttctcaaatt tttgtgaaaa ttcggcttat
    31561 ttttcgaaga ggctacttct gaaacaccga gaataaaaaa tgtgaaaaag ctgttctgca
    31621 cccagtaata agaacaatca aaaagggaac atggaacaca tttatcctgt ttccctgttc
    31681 cctttttgat gtattcgagc ataaataaaa taccttcgtt acctactatc ttctgtactt
    31741 ggtaaacctt agtcaattgc cttttttaac gcttgacgaa aagacatatg atctttctcc
    31801 gtaaagggtt ttggaccctt tgtccttatg ccagcttttc ttaactttcc actatgataa
    31861 cgttgttcta gaagcgtgcc gatattcgct tcgtcaaatt cttttccaga gtgatggaac
    31921 actcgcacac ccttcggcaa tacaagtgaa gctaaaccat aatcttgcgt gatcaaaaag
    31981 tcattcttct taaccatacc gacgatttta taatccgcac tatcagctcc gcggtctacg
    32041 tagacgattt ggacatgatt agcgtattct ttggtcgtat aatggtccac actggtcacg
    32101 ataaccacgt caagaccata ggattctcct aattttatga catcttcttt tactggagaa
    32161 ccatctccat caatgaatag cctcattctt tttcgccttc ttccataaat gataaacagt
    32221 tactaatccg ctcagtaaaa gaccaacatt gatccatttt gccaagataa gcagttgtac
    32281 actttctatc ggcactgatt catggttcag cgtgatcaat aatagatgga ttggctctcc
    32341 catttctttt gctaaaacaa acaaaagcgt catcaataaa aactggtgga tcacactccc
    32401 tttattttga gtagtatact tgacaacgat ccggcgatcc attggaatag ctgtatcagt
    32461 ttgataatat tccttattta gccagctgcc tgttactacg tgccagaaac taagcagaaa
    32521 gacacctatc gcaaaaccat ttggaatcaa gaggaccaat aaagaagaac tcagtccaag
    32581 caattgcata gccaatggag accatgttaa acgtttcaaa atccatggtc cgactatttt
    32641 tgctgcaatc aagcctgctg cataaggcaa atacataaaa atcgaaagtt tttctaatcc
    32701 gtacagtatg ccaacataaa aactgctaaa taaaaaaagg aaattcccta gcattccatt
    32761 tagaaaagta aacagattta gccagcttgg caacttccat tccttcttct ggtgtcctaa
    32821 aacaaacacg aacaagatga acagcagcaa gaaaccataa atagcaagat caaaaagcct
    32881 ttcatcgaat aacaatcggg catttctcaa aagaaacaat aagccaaaga atatcaaaaa
    32941 taaaacaagc tctcgcgtag ctaccagatt tcttttgatg tctttgaaat ccagttcgta
    33001 acgcggataa tgactaaccg tatggtaggc catgacgtaa aaaagtgtat aaatagtaaa
    33061 gcttgctgca atctgagtcg gtgcaggcaa ctcaatcgct tgatacagga gaaatagcca
    33121 gatagctgca aataagtact ttttcccatc catattgata aaaccttgcg tcttttcgtg
    33181 aaaattgacc gtggtattag caggtacaag ccatgctgca ctcagcccta gcaaaacact
    33241 tgaaaaataa aataaaggaa aataaaatac gcctaatatt ccaagcaatg aaccagcacc
    33301 accaatcagc agagcgatca tcagcaacgt gtaactatct agaccaaatc gtagactgtt
    33361 gactaaaaat agtccagtca tccgaaaggc ataaaacagc gtaaatggca aaatcgtcag
    33421 ccaattatgc gagtctgtta gtcccaaaaa taaaagataa ggaataaaaa taaccgtgtt
    33481 acttaagata aagggcgttg tttgtgtaaa attacgccca aatcgtttga gtttttcgaa
    33541 catgacaatg gctccttaaa cagtcttata actaatctgc tcttcgattt tagcattaaa
    33601 ggggaaataa accaatttta cagaatatat tcttgtaaaa aaaaatacag aaagaagcat
    33661 aagcttcttt ctgcattttt acggtacttg attactcaag cagacaagcc cttctccaca
    33721 aaagtcttgc ccgacacccc tgcatccggc aggtgataaa gatagaaatc aattatcctg
    33781 tgcctccaaa atcaattagg agctctgtaa accagagtcc ttctcgaccc gtcgcataaa
    33841 tttactttaa cacagttcct atgtttatgc gagagctttt ttcattttat aatcgaccat
    33901 ttgaaatcct tgaccgatat ctgaaataag ttcttctgta atctcaaatc cttcatgctt
    33961 ataaacctcg attgcttgat gattcccctg attcactcgc aaaaagatct ctctttcctt
    34021 tgtttgcgca gcaagttctt cataccagcg aaaaactgaa gaagtcaatc cttgaccacg
    34081 tactttattt agcaaatata atttacttaa ataaattttt ccatttatct cttcataagc
    34141 agtgtaaccg acagtctttt cttcgctttt taataaaaag taggacacac cttctgtcag
    34201 ttctttttga atctgttttt ttgactgata agttttcagc atgtaatcca cttgtttttg
    34261 accaatgatc ggcacaaaag cttccggcca tacttcttgt atgactgcca tcagctcatc
    34321 cagttcattt tctgttactt ttattttttc catacaccca cgtccttttt tacattataa
    34381 atgaccttgc gcttgatgga ataaaaagag catgatcatg ctatacacac ccaccgacca
    34441 tggtttcaag aaaatcacaa tctgcataaa ttccctaaaa gataatttcg tcaaaccagc
    34501 tactagacag atcaagtcgt ctggcgcaaa gggaagcagc aaggtaacaa ctagtacttt
    34561 tttaatatct ttcgtttttc ttgtcagcaa ttcatcaaat ttctgatact tttttggcga
    34621 taaaataagc tggacaaagg ctacgccata gtaacggaca agcaaaaatc cgattgcttc
    34681 cccaatcact aggccaatac aactatataa aagcccaaat ccattgccaa acatcagcat
    34741 gcccgctact gaggagatcc ctcccggcaa aataggaatg atcacttgga tcacttgcaa
    34801 cagaacaaat atcatcactg catacttgcc aaattgctgg ataaacgctt gcaaagacgt
    34861 gctcgatcga aaaatcccat gatgataagc ataaagaatc aacacaaaga aaaaaaacag
    34921 accaataatg ggcatgatct gaagacattt ttgtaaaact gatccttttt tagacatcta
    34981 tattccccac atcttttttc atttattaaa actgcctcc
//
LOCUS       DAFBVQ010000025        32658 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.025, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000025 DAFBVQ010000000
VERSION     DAFBVQ010000025.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 32658)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 32658)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..32658
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.025"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            161..391
                     /locus_tag="LLC22_001379"
     CDS             161..391
                     /locus_tag="LLC22_001379"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1146 domain-containing protein"
                     /protein_id="HBK5434664.1"
                     /translation="MQVYGIDAVLRIVSHLAFIYLAFWSLRSLRIETFFRPMHNTQIR
                     MAIVLFSIFLGYTASNFFLEVIALCRNLFVSL"
     gene            488..1789
                     /gene="murA"
                     /locus_tag="LLC22_001380"
     CDS             488..1789
                     /gene="murA"
                     /locus_tag="LLC22_001380"
                     /EC_number="2.5.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734894.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine
                     1-carboxyvinyltransferase"
                     /protein_id="HBK5434665.1"
                     /translation="MEEIIVRGGNQLNGTVRIEGAKNAVLPILAASLLAEEGITTLDN
                     VPILSDVFTMNQVIRHLNVDVDFDEQKNQVTIDASRQLEIEAPYEYVSQMRASIVVMG
                     PLLARNGHAKVAMPGGCAIGKRPIDLHLKGFQALGAKIIQKNGYIEAIADELIGNTIY
                     LDFPSVGATQNIMMAAVKAKGTTIIENVAREPEIVDLANILNKMGAQVYGAGTETMRI
                     EGVDHLHAVNHSIVQDRIEAGTFMVAAAMTQGNVLIADAISEHNRPLISKLIEMGAEI
                     IEEEGGVRVIGPKHILPTDVKTMPHPGFPTDMQAQMTAIQLVAEGTSVVTETVFENRF
                     QHLEEMRRMNAHVKIDGNVAIMDGNHELQGAEVYATDLRAAAALVLAGLKANGITRVR
                     NLNYLDRGYYNFHIKLQQLGADVERVDMDQTSAEKTAQTIA"
     gene            1802..1978
                     /locus_tag="LLC22_001381"
     CDS             1802..1978
                     /locus_tag="LLC22_001381"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit beta"
                     /protein_id="HBK5434666.1"
                     /translation="MSNQRYILLTLIKILMVILLLILLFVAGTMIGYGVIGGGNPFKV
                     FQPSLWIHIRDFFH"
     gene            2113..2409
                     /gene="yidD"
                     /locus_tag="LLC22_001382"
     CDS             2113..2409
                     /gene="yidD"
                     /locus_tag="LLC22_001382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertion efficiency factor
                     YidD"
                     /protein_id="HBK5434667.1"
                     /translation="MKKILIYLVRGYQRFISPAFPPSCRYYPTCSNYMIKAIQTHGAL
                     KGTVMGTARILRCHPFVKGGIDYVPLTFRLTRNKKDKKEPDYKKVVKNTGSTER"
     gene            2594..3061
                     /locus_tag="LLC22_001383"
     CDS             2594..3061
                     /locus_tag="LLC22_001383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434668.1"
                     /translation="MIEELNKKDLPWSLLLDADPDKEKVQVYVSRGSGWIWKEKEKTI
                     GVLIYVAREKEYEIVNVAVTPTYQGKGIGGKLLETAFQKLSQLASSQTQIIIRTGSTS
                     SAALHLYQKMGYVEIGRVKDYFIHHYSEPIFENGDQLRDQVILAIHLPKNSFN"
     gene            3146..4030
                     /locus_tag="LLC22_001384"
     CDS             3146..4030
                     /locus_tag="LLC22_001384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325063.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5434669.1"
                     /translation="MGILVFDFGGSAVKYGCWDGKEIKGKGQFATPESWEEMKAQLFQ
                     VYKKILVSFEVEGIGISSPGVVNNEKQVIEGISAIPYIHGFNIFRDLETLFQLPVTIE
                     NDANCAGMAEFYEGAARDYQDVAFVVAGTGIGGALFTKGQINKGAHLYGGEFGLMFLN
                     GDKTFSKLGTAVQMAWRYCERKGLDKNAYTGKDVFELAETGDAIAKEEVESFYTYLTK
                     GLFSIQFSFDPEVIVLGGGVSAKEGLIDEIKSRMKKLTEQFDLHDFEPQILLCEYRND
                     ANLVGAAANYLAVRQGEN"
     gene            4144..4380
                     /locus_tag="LLC22_001385"
     CDS             4144..4380
                     /locus_tag="LLC22_001385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2969 domain-containing protein"
                     /protein_id="HBK5434670.1"
                     /translation="MMSKKNKDIEVRIEEVKKDIKGKNYEVTQLFIGKKMIGEILAYG
                     PKEYEIFFGEEDFGKEKSLENAIETVIRHWNLHE"
     gene            4468..4548
                     /locus_tag="LLC22_001386"
     tRNA            4468..4548
                     /locus_tag="LLC22_001386"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4502..4504,aa:Tyr,seq:gta)
     gene            4555..4626
                     /locus_tag="LLC22_001387"
     tRNA            4555..4626
                     /locus_tag="LLC22_001387"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4587..4589,aa:Gln,seq:ttg)
     gene            4751..4921
                     /locus_tag="LLC22_001388"
     CDS             4751..4921
                     /locus_tag="LLC22_001388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292784.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434671.1"
                     /translation="MKWKEKVDEAAEKLYDLVKSEKYNIEVNIPKKGGKAVRVKSKRP
                     TNHTKKWMAKNR"
     gene            5141..5848
                     /locus_tag="LLC22_001389"
     CDS             5141..5848
                     /locus_tag="LLC22_001389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737976.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5434672.1"
                     /translation="MSNQLPVYIQIHDQLKNEIEQGIWKVGDRLPSERELAVKFNVSR
                     MTLRQAIQNLADEGILERKIGSGTYVAREKVQEKMSGATSFTEIMESQNRVPSSRTIS
                     YFLTSPSSSEMEKLNLSKDDTILRMERIRFADDVPICFEVASVPQKLIDGYSKAEITE
                     SLYRTLEEKGGKKIGPANQTITAVLASEKIADYLEVKRGDAVLRLRQISYFEDGTPFE
                     YVRTQYVGNRFEFYLEK"
     gene            complement(5907..6551)
                     /locus_tag="LLC22_001390"
     CDS             complement(5907..6551)
                     /locus_tag="LLC22_001390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YigZ family protein"
                     /protein_id="HBK5434673.1"
                     /translation="MIERYRTIKENGQSEIEIKKSRFICSLRRIESEDEAKSFIQEIK
                     KEHWKANHNCSAFIIGEKNEIQRSSDDGEPSGTAGIPMLEVLKKNQLINVAAVVTRYF
                     GGTKLGTGGLIRAYTHAVSQALSDIGIVEGTLQQEISVMITYPQLGKLQNYLELQHFF
                     IKEIQYTDQVSVICAVDEKSADHFKESIIELLNGQVQFEEGPVSYHEQLVTDHI"
     gene            6677..6964
                     /locus_tag="LLC22_001391"
     CDS             6677..6964
                     /locus_tag="LLC22_001391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434674.1"
                     /translation="MQERMKKYDAITHYLKNNGGSQVTLTFTQFDELLFPSNGLPKTA
                     RESTDWWANDYKHPEKGAYGWINAGYEVVVINLDKEYVVFNKLVKSSWLFD"
     gene            7072..7392
                     /locus_tag="LLC22_001392"
     CDS             7072..7392
                     /locus_tag="LLC22_001392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5434675.1"
                     /translation="MAKKTIMLVCSAGMSTSLLVTKMQKAAEAKGIDSDIFAVSASDA
                     DNNLANKDVDVLLLGPQVRFMKADFEKRLEPKGIPLDVINMADYGMMNGEKVLDQAIT
                     LIGE"
     gene            7473..8786
                     /locus_tag="LLC22_001393"
     CDS             7473..8786
                     /locus_tag="LLC22_001393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306206.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBK5434676.1"
                     /translation="MNHFWGRRLLTRDIKAIDCEEVNLPNYEKIAAVERLSNWILCHR
                     CGMRTSVIDGQLADYGYFCTHCLYLGRCDTQQDLYLFDQPEAKPREVVFFWTGQLTEK
                     QTEISKRILCHSEKRHHLIWAVTGAGKTEMLYPILVETLKAGGRVAICTPRVDVCNEL
                     FLRYRYVFPEEKITLLHGNTATAYTFTSFVICTIHQLYRFYRSFDLIVIDEIDAFPYN
                     GDAGLAHAVQTAIKPDGRFIYLSATPDKKLLKEIKQTFDIHKLALRFHRRLLPEPVLV
                     FMNNWRQKCKNKKKIKSLVRIIHQLIKENHILLFCPSITMMHRLKATLQEALPRYEIT
                     DVSSRDNQRAEKVQKMREAKYDILLTTMILERGVTFERISVIVLGADHPVFTKSSLVQ
                     IAGRADRKGPYTNSQVYFFYEEKTAAIRKACQEIKEMNEEGKKIL"
     gene            8783..9502
                     /locus_tag="LLC22_001394"
     CDS             8783..9502
                     /locus_tag="LLC22_001394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ComF family protein"
                     /protein_id="HBK5434677.1"
                     /translation="MRCSCCSKDIVQNLTFSEIIGVSKYRLPQTCSVCRAQFHLLETR
                     GCSGCQKPIHFNLESTKKKVNSIPVYCSDCQEWKKKYPTYDFQHRAFFVYDENMKAWL
                     NQYKFMGDIRLAGTFAYKWTQIKKEYPTYIYCPIPLSEKRRTERGFNQVSEMLKAARI
                     PFQMLLKREKHLLAQAKNTRKERLEMPQPFELAVTFSKIQNKKILIIDDVYTTGQTLF
                     HAADCLQIAQPKIIRTISLAR"
     gene            9630..10181
                     /gene="raiA"
                     /locus_tag="LLC22_001395"
     CDS             9630..10181
                     /gene="raiA"
                     /locus_tag="LLC22_001395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome-associated translation inhibitor RaiA"
                     /protein_id="HBK5434678.1"
                     /translation="MFRYNVRGENIEVTEAIRDYVEKKVGKLERYFSDAPDATAHVNL
                     KVYTEKTAKVEVTIPLPYLVLRAEETSPDLYASIDLVVDKLERQIRKFKTKINRKSRE
                     TGMNTANAAALFNEEDENENDSELDIVRTKRLSLKPMDSEEAVLQMNMLGHNFFIFED
                     AETNGTSIVYRRKDGKYGLIETD"
     gene            10403..12937
                     /gene="secA"
                     /locus_tag="LLC22_001396"
     CDS             10403..12937
                     /gene="secA"
                     /locus_tag="LLC22_001396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecA"
                     /protein_id="HBK5434679.1"
                     /translation="MANLIRSLIENDKKELKRLDSIAKKVEAYADQMAALTDEQLQAK
                     TAEFKGRYQKGETLDQLLPEAFAVVREAAKRVLGLYPYHVQLMGGIVLHDGNIPEMRT
                     GEGKTLTATMPVYLNALTGEGVHVVTVNEYLATRDSTEMGELYNFLGLTVGLNINSKS
                     SDEKREAYNCDITYSTNNELGFDYLRDNMVVYRHQMVQRPLNYAIVDEVDSILIDEAR
                     TPLIISGQAEKSTALYTRADNFVKRLKEEEDYKIDVQSKTISLTEAGIEKAEETFGLD
                     NLYDIENTALTHHLDQALRANYIMLLDIDYVVQDGKVLIVDQFTGRIMDGRRYSDGLH
                     QAIEAKEGVEIEDETKTMATITFQNYFRMYKKLAGMTGTAKTEEEEFREIYNIQVYQI
                     PTNRPVIRDDRPDLLYPTLQSKFHAVVQDIKDRYRKGQPVLVGTVAVETSELLSDMLN
                     QERIPHEVLNAKNHFKEAEIIMNAGQKGAVTIATNMAGRGTDIKLGLGVRELGGLAVI
                     GTERHESRRIDNQLRGRAGRQGDPGMSQFYLSLEDDLMKRFGSERIKAFLDRMKIGEE
                     DAVIQSKMLTKQVESAQKRVEGNNYDTRKNVLQYDDVMREQREVIYKQRQEVIMEEKS
                     LSKPLMNMVKRTISRVVDAHTQLEKENWNLESIIDFAGSTLVHEDSITLADIEGKTAQ
                     EIKEYLNERAQEVFNTKAAQLNGPEQLLEFEKVVILRVVDSKWTDHIDAMDQLRQSIG
                     LRAYGQNNPLVEYQTEGYKMFEDMVGAIEYEVTRIFMKAEIRQNVQREQVSQGTASHS
                     EDGDAKENSNTSAKKQPIHVNKVGRNDPCPCGSGKKYKNCHGKNAN"
     gene            13063..14164
                     /gene="prfB"
                     /locus_tag="LLC22_001397"
     CDS             join(13063..13134,13136..14164)
                     /gene="prfB"
                     /locus_tag="LLC22_001397"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_139124933.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 2"
                     /protein_id="HBK5434680.1"
                     /translation="MEISEIRNLLTEMQEKVTSFRRSLDLDQLEEDIAEAEAKMAEPG
                     FWDDSEAAQKVISENNANKETYDQFHSLAEELEEIELMVEMLQEEPDAAMQEEAETRI
                     NALDEKMKTYELSMLLDGPYDRNNAIVELHPGAGGTESQDWGSMLLRMYTRWAEQHGY
                     QVETLDYQAGDEAGIKSVTLLIKGHNAFGYLKSEKGVHRLVRISPFDSAKRRHTSFCS
                     VDVMPELDETIDIEINPDDLKIDTYRASGAGGQHINKTESAVRITHLPTGTVVASQAQ
                     RSQLKNREQAMGMLKAKLYQLEVEKKEQEAAALRGEQKEIGWGSQIRSYVFHPYSMVK
                     DHRTNVETGNVQAVMDGDLDLFIDGYLKMHLQ"
     gene            14269..14955
                     /gene="ftsE"
                     /locus_tag="LLC22_001398"
     CDS             14269..14955
                     /gene="ftsE"
                     /locus_tag="LLC22_001398"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell division ATP-binding protein FtsE"
                     /protein_id="HBK5434681.1"
                     /translation="MIEMKDVMKKYSNGTTAIRNLSIVIEQGEFVYVVGPSGAGKSTF
                     IKLMYREEKASKGTLNVAGHDLIAIKNREVPYLRREIGVVFQDYKLLPRKTVYENVAY
                     AMQVIGRKPRDIKKRVMEVLDLVGLKHKVRVFPSELSGGEQQRVSIARAIVNTPKVLI
                     ADEPTGNLDPENSWEIMKLLDRINAQGTTVVMATHNSTIVNTIRHRVIAIENGRIIRD
                     QAEGEYGYDD"
     gene            14939..15832
                     /locus_tag="LLC22_001399"
     CDS             14939..15832
                     /locus_tag="LLC22_001399"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434682.1"
                     /translation="MDTMIRTFFRHLLESIKSLKRNGWMTVASVSAVTITLTLVGVFM
                     AVIMNATKLAQDIEGNVDVSVFVDIGTKDEEMKKLEKELNDLDHVKKVEFSSKEQELK
                     KIQNEMGDSWKLFEGDNNPLYDVYVVSATDPSYTKQVAEEAADLKNVSRSDYGGASSD
                     RIFQIAGAVRTWGLVAAALLLFVAMFLISNTIRITILSRQREIQIMRLVGAKNGYIRW
                     PFFLEGGWIGLIGAILPILIITFGYAWFFQLINPSLLRSHYSLIHPQNIVWKINLLMV
                     GIGVIIGSLGSIISMRRFLKF"
     gene            15984..17432
                     /gene="cls"
                     /locus_tag="LLC22_001400"
     CDS             15984..17432
                     /gene="cls"
                     /locus_tag="LLC22_001400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010782552.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cardiolipin synthase"
                     /protein_id="HBK5434683.1"
                     /translation="MKIIVDNFFTILLIMNILLSFIIVFRERKETAQTWAWLLVLMFI
                     PVVGFILYIFLGRGISKEKIFDLKIQGKIGKNLEIEEDKQALMRGLYPHPPTGQVDVK
                     QLIYMLTVFESTLYTTKNEITLFTDGREKFDALIEDIKQAEDHIHFQYYIYRSDALGE
                     EVRDALTEAARRGVKVRVLLDAWGSTQVSSSFFQNLKKAGGEIAFFFPLFVPYINPRI
                     NYRNHRKIVVIDGKIGYTGGFNVGNEYLGLVKKFGYWRDNHLRIYGEAVYILQNRFLM
                     DWNSQHTKEVGYSPKFFPSIHSTGDIAVQIVTSGPDTEHEQIKMTYLKMISLAKREIL
                     IQTPYYIPDGSIHEALKLALLSGVKVHIQIPNKPDHLLVYWATYSFAAELIEYGARIE
                     TYENGFIHAKTMIIDGGIVSVGSANIDVRSFRLDFEVNTLIYDERMASRVRKAFFEDS
                     KISTHLTKEMYENRGIIIKMKEGLARLISPLL"
     gene            17769..18626
                     /locus_tag="LLC22_001401"
     CDS             17769..18626
                     /locus_tag="LLC22_001401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292763.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS"
                     /protein_id="HBK5434684.1"
                     /translation="MKKLKLFLPIIGLAILLSGCSKWIDRGESITAVGSSALQPLVET
                     VAETYQTENPGKFINVQGGGSGTGLSQVQSGAVDIGNSDLFAEEKSGIDASALVDHRV
                     AVVGITPIVNKDIGVKDISMENLKKLFTGEIKNWSEVGGKDQPVVILNRASGSGTRST
                     FEKWVLDGETAVQAQEQDSSGMVRQIVADTPGAISYVAFSYVSDDVDTLNVNGVEPTD
                     ENVTTNKWTIWAYEHMYTRDHPKKLTKEFLDYILSDEVQDNIVGELGYIPVSHMKVER
                     DWQGNIVKE"
     gene            18741..19661
                     /gene="pstC"
                     /locus_tag="LLC22_001402"
     CDS             18741..19661
                     /gene="pstC"
                     /locus_tag="LLC22_001402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease subunit PstC"
                     /protein_id="HBK5434685.1"
                     /translation="MEDVKKVLLTKSKRSKMEQRGKFISFLCIALIVLVVLSIFYFVA
                     SKGLATFFTDKINVFDFLFGTDWNPSQIGANGKPMVGALPMITGSFIVTFLSAIVATP
                     FAIGAAVFMTEISPKNGTKILQPVIELLVGIPSVVYGFIGLSVIVPFVRSIFGGTGFG
                     ILAGTFVLFVMILPTVTTMTVDALKAVPRHYREASLALGATRWQTIYKVVLRAAVPGI
                     LTAVVFGMARAFGEALAIQMVIGNAALMPTGLTTPASTLTSILTMGIGNTIMGTVENN
                     VLWSLALILLLMSLFFNIVIRMIGKKGELK"
     gene            19661..20545
                     /gene="pstA"
                     /locus_tag="LLC22_001403"
     CDS             19661..20545
                     /gene="pstA"
                     /locus_tag="LLC22_001403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010764435.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter permease PstA"
                     /protein_id="HBK5434686.1"
                     /translation="MNAKRSDKIATGVLYVVSGIIVLILAALLLYILVRGIPHISWSF
                     LTEPSKAYQEGGGIGIQLFNSIYLLLITMIISFPISLGAGIYLSEYAGKNWLTDVIRT
                     SIEILSSLPSVVVGLFGFLVFVIQFQYGFSIISGALALTVFNLPLLTRTVEESLQAVH
                     YTQREAGLALGLSRWETVIKVVVPEATPGILTGVILSSGRIFGEAAALIYTAGQSAPA
                     LDFTNWNPLSVSSPISIFRQAETLAVHIWKINTEGTMPDGVSVSAGASAVLIIAVLLF
                     NFGARAIGKRLYRKMTSA"
     gene            20560..21366
                     /gene="pstB"
                     /locus_tag="LLC22_001404"
     CDS             20560..21366
                     /gene="pstB"
                     /locus_tag="LLC22_001404"
                     /EC_number="7.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002408906.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBK5434687.1"
                     /translation="MKKYNWNETNVITMPKEKEVALYTDDLHVWYGDNEAIKGVDLEF
                     EKNKITALIGPSGCGKSTYLRSLNRMNDGIANTKITGKIMYQGVDINAPQVDVYEMRK
                     RIGMVFQRPNPFSKSIYDNITFALKQHGEKNKKKLDEIVETSLKQAALWDQVKDSLDK
                     SALALSGGQQQRLCIARAIAMKPDILLLDEPASALDPISTGTVEETLVNLKEDYTIII
                     VTHNMQQAARISDYTAFFYLGKVMEYDKTNKIFTRPKIQATEDYVSGHFG"
     gene            21382..22140
                     /locus_tag="LLC22_001405"
     CDS             21382..22140
                     /locus_tag="LLC22_001405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317877.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter ATP-binding protein"
                     /protein_id="HBK5434688.1"
                     /translation="MTKEIISSKDLHLYYGKKEALKGIDLSFNQGEITAMIGPSGCGK
                     STYLRSLNRMNDLIPNVTITGSVLYKDKDIYGPKTDVVELRKEIGMVFQQPNPFPFSI
                     YENVIYGLKLKGEKDKKVLDQVVEESLKAASVWDDVKDKLHKSALSLSGGQQQRVCIA
                     RVLAVNPEIILLDEPTSALDPVSTGKIESMLLELRERYTMIIVTHNMSQASRISDKTA
                     FFLDGHLIEYNDTKKIFMNPEKQETEDYISGRFG"
     gene            22153..22830
                     /gene="phoU"
                     /locus_tag="LLC22_001406"
     CDS             22153..22830
                     /gene="phoU"
                     /locus_tag="LLC22_001406"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010723432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate signaling complex protein PhoU"
                     /protein_id="HBK5434689.1"
                     /translation="MLRTQFEEELLNLHNQFYEMGMMVSSAVHKSVRAYIKHDKILAQ
                     EVIENDININNMETRLEKKSFEMIALQQPVTTDLRMIITVMKASSDLERMADHAVSVA
                     KSTIRVKGQTRIPEIEKEISDMSDYVKKMVDNVLVAYVKTDEKDARTIANMDQRVNDY
                     FNRIYNATIKNMQENPETVISGTDYLNVASYLERIGDYVTNICEWIVYLATGKITELN
                     TNHNEIF"
     gene            23067..24098
                     /locus_tag="LLC22_001407"
     CDS             23067..24098
                     /locus_tag="LLC22_001407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBK5434690.1"
                     /translation="MQKKISIITIFFICVLTSWVIQHQAALYEVPVIEIEKVRIKEDH
                     QLITGRLMNTNQKGESIYLSVPYQKNQIETANIKARQMYLVQMHGDEWQLVAKKNDGW
                     LFFFTSIFIGAMLLIGGKHGLFALGSLIINIVLLLLLLLIFTKIEGISLLNISILFVV
                     IGMIISILALDGWNRSSIIKISAAVTSVFLAFFICLLTMNLWKDQGLRYEELNYLTRP
                     YRSVFLSSVLIGTAGGTLDTVITVIATLEELTKRQPEITAKQLWLSGRQVGRDVIGSM
                     TNILLFVYISGSVPSLLLYLGNQWSFKETIEQHLSLEFLRVIAGSLGIVLSIPISVLF
                     FLTVRRLKR"
     gene            24095..24862
                     /locus_tag="LLC22_001408"
     CDS             24095..24862
                     /locus_tag="LLC22_001408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YibE/F family protein"
                     /protein_id="HBK5434691.1"
                     /translation="MNVLIILVGILAISVLLIGGTQGMYILLGLFINLGIFFLLLFGY
                     HQKWPILALSVIGFLLIAVVILFFINGYNLKMRAAFVSILIFLFCFLLLLPITDFLAI
                     QGFTTIELEELSGLDKTLAIDFRLLTRSLLLISLSGAVLDASVAISSGTFEVYQANPQ
                     LSFYQLRHSSFAIAKKILASTVMTLLFAFMGSSLALILWFIDLDIPFQQVINEKSFVL
                     EYTMAILTTLSALLVLPLTCVTTAYLFTKKKEQLKME"
     gene            24962..26530
                     /gene="liaX"
                     /locus_tag="LLC22_001409"
     CDS             24962..26530
                     /gene="liaX"
                     /locus_tag="LLC22_001409"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="daptomycin-sensing surface protein LiaX"
                     /protein_id="HBK5434692.1"
                     /translation="MKERERILDLVKKGILSTEEGLDLLESMATEKDEKQIKKEADKV
                     TASHKEKDQASQLIDKLENGEEEISEPVDPKERERQDQENLEKILDELATEANKTSAR
                     LDEVNAQFADNKAARNEKQEALMQLNTKEELGELTEEELAQRQTLEAEIKELEASGDT
                     LLEEQLKLEAELKDIRKNQWSEKKETFTDKFELPDDWKDQATDTLNQVGEKMSEAGSQ
                     LGKFLKKTFQTVSETVNDNMEWKDVSLRVPGIATTKFEHEFYYEAPAASILDIKAANG
                     NVTLKTWDSNDVKVEAKIKLYGKMGAEPFEAFSERSQIEVNEDHISFQIPNKRVRADL
                     VFYLPKRVYDHAAIKLLNGNIMIETLEAKDIYTKSTNGNIIVDQLTATMLEVEGVNGN
                     IDIRNGNILDSIIETVNGTVTFGATAENLSVSLVNGDVRLTIKEDNLKKVEASSVNGN
                     VKVALPDGIGLEGHAKTSLGSINSRLSNYEVVREKKERTNQMLQFRRVSDGEIAQVQL
                     STTTGSIYLKDTDK"
     gene            26827..27147
                     /locus_tag="LLC22_001410"
     CDS             26827..27147
                     /locus_tag="LLC22_001410"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629442.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PspC domain-containing protein"
                     /protein_id="HBK5434693.1"
                     /translation="MMKKKLTKSNKNVVLTGTLAGIGEYIGIDPTVIRVLYVFLSLVA
                     FGSPIILYILLALIIPSARSARTNYGHNNAYYEKNNYREQTREQTKKRKEAEKIDDDE
                     WSDF"
     gene            27147..27497
                     /locus_tag="LLC22_001411"
     CDS             27147..27497
                     /locus_tag="LLC22_001411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin family protein"
                     /protein_id="HBK5434694.1"
                     /translation="MSYFQRILVNTLTFISLAVLFPAMVHVSSIWTAVLASFVLSVLN
                     MFVKPILTILSLPFTLVTLGLFTFVINAAILKMTSFFVGAEHFSFSSFGAALLVAILM
                     SLVNVIVSEHNSRK"
     gene            27664..28602
                     /locus_tag="LLC22_001412"
     CDS             27664..28602
                     /locus_tag="LLC22_001412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HPr kinase/phosphorylase"
                     /protein_id="HBK5434695.1"
                     /translation="MSEVVKVSQLVKKLSLEIVTGDEKSLDRVIVTGDISRPGLELTG
                     YFNYYSHNRLQLFGSKEISFAERMIPEERLIIMRRLCSEDMPAFIISRGLPAPEEMIQ
                     AANENGIAVLRSPISTSRLLGELSSYLDGRLAPRTSVHGVLVDVYGLGVLIQGDSGIG
                     KSETALELIKRGHRLIADDRVDVYQQDELTVIGEPPKILEHLIEIRGIGIIDVMNLFG
                     ASAVRGSMQVQLAVYLEAWAKDKKYDRLGSEDTTVEIAEVGIPQIKIPVKTGRNVAII
                     IEVAAMNFRARTMGFDATKTFEERLSRLIEENSGND"
     gene            28617..29447
                     /locus_tag="LLC22_001413"
     CDS             28617..29447
                     /locus_tag="LLC22_001413"
                     /EC_number="2.4.99.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolipoprotein diacylglyceryl transferase"
                     /protein_id="HBK5434696.1"
                     /translation="MLAQINRVAFELVGIPIYWYALIIVSGIIIAMWLSSREAVRVGL
                     KADDVTDFMLWGLPISIIGARLYYVLFDLPQYIADPIQIFNIRSGGLAIYGGLIAGAI
                     TLYFFTKYHFISLWTFLDIAAPSVLLAQAIGRWGNFMNHEAYGPDTTRSFLESLHLPQ
                     FIIDNMYIEGIYRQPTFLYESLWSLIGFILLLFLRKKPHLLKKGEVLLCYLMWYSFGR
                     FFIEGLRTDSLYFLGVIRISQLLSAVLFVGTLILFIWRRKKGNLPDYDRSLGKNQQII
                     "
     gene            29491..30516
                     /locus_tag="LLC22_001414"
     CDS             29491..30516
                     /locus_tag="LLC22_001414"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBK5434697.1"
                     /translation="MNYRVAVLGPGSWGTALAQVLAENGHDVRIWGHRASQVEEINTQ
                     HTNQRYLPDHCLPDSIQAFTNMEDAVKDADAVLFVIPTKAIRSVAKELVPKLNTKPVI
                     IHASKGLEQGTHKRISDILLEEIPVEKRKAVVVLSGPSHAEEVAKHDITTITAASTDA
                     KAAKYVQELFMNNYFRIYTNPDVIGVEMGAALKNIIAIGAGAIHGLGFGDNAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLVVTCTSVHSRNWRAGNLLGQGQPLEEVLA
                     NMGMVVEGVNTTQAAMELAQIMEIEMPITQTIYEVLYEQKEIKTAAKEIMLRDGKKEN
                     EFSLTIF"
     gene            30531..31469
                     /gene="galU"
                     /locus_tag="LLC22_001415"
     CDS             30531..31469
                     /gene="galU"
                     /locus_tag="LLC22_001415"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBK5434698.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LKSGIEDILIVTGKAKRPIEDHFDSNIELETNLSEKGKTELLKLVEETTDVNLHFIRQ
                     SHPKGLGHAVLQARAFIGNEPFVVMLGDDIMEDEVPLTQQLIDDYERTHASTIAVMQV
                     PHDETSKYGIINPGEVLEDGLYNVKNFVEKPDPSKAPSDLAIIGRYLLTPEIFDVLSE
                     QQPGAGNEIQLTDAIDTLNKTQRVFARKFTGKRYDVGDKFGFMKTSIEYGLTHPEVGA
                     PLREYILSLGKTLEAEGSKIDHNPKGITEIKEEKKK"
     gene            31594..32034
                     /locus_tag="LLC22_001416"
     CDS             31594..32034
                     /locus_tag="LLC22_001416"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF948 domain-containing protein"
                     /protein_id="HBK5434699.1"
                     /translation="MSGGEIAGLIAAIAFAILVVFIVRVLLQVSKTLEKVDQTVAEAN
                     TTIEIVTKDVDLLSRQVEGLLVKSNELLLDINGKVATIDPLFTAVADLSESVSELNHS
                     SKNIATKVGGIGKTTAKATVAGKVGGTAMKFFKNKKHTETTGGK"
     gene            32037..32639
                     /locus_tag="LLC22_001417"
     CDS             32037..32639
                     /locus_tag="LLC22_001417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YtxH domain-containing protein"
                     /protein_id="HBK5434700.1"
                     /translation="MAKKGGFLLGAVVGGTAAAIAALLLAPKSGKELRDELAAQADDL
                     MDMASDYTDMAKEKSTELTGIAKEKAQDLSQQAGDLAGSVKQKVSESADEAGSESDDI
                     LLNLKEQSADLSNRFKKTAEDMKKPADELGSIAKDTSEDIIIDVKDAAGKAGDTVNEG
                     MSEAKPVADDSKEMMKMAKEDAKEAKKEIKDTMTDSSTNH"
BASE COUNT        10840 a         5540 c         7079 g         9199 t
ORIGIN      
        1 tttgtctcag tccctttttt tgcatatttt tagcatttat ttcctaaaaa atgtaagggg
       61 attcctatat ttttaagtat acttgttttt ccttttatac attttatggt attatcattt
      121 tattagttat tataaaacaa tcgttagaaa ggacgtcatt atgcaagtat acggaattga
      181 tgcggtgctt cgaatcgtga gtcatttggc gtttatctac ttagccttct ggtctttacg
      241 ttcgttacgc attgaaactt ttttcagacc aatgcataat acgcaaatta gaatggcaat
      301 cgtacttttt tcaatttttt tagggtacac tgcaagtaat tttttcttag aagttatcgc
      361 tttatgccga aatcttttcg ttagcctgta aattttaaaa aaaggtacta ttttaaaagc
      421 aaggatgtta taatagaaaa gattttgagt aagtgtatgc tcattggaat tttttggagg
      481 gaacaacatg gaagagatca tcgtaagagg tggcaatcaa ttaaatggaa cagtaagaat
      541 tgaaggagct aaaaatgctg ttttgcctat tttagctgct agtttgttag cagaagaagg
      601 tattacgaca ttagacaacg ttccgattct ttctgatgtc ttcactatga atcaagtgat
      661 tcgtcactta aacgtagatg tagattttga tgaacaaaag aatcaagtaa caatcgacgc
      721 ttcaagacaa ttagaaatcg aagcgcctta tgagtatgtt agtcaaatgc gtgcttcaat
      781 cgttgtgatg ggtccgctac ttgccagaaa tggacatgca aaagtagcta tgcctggtgg
      841 atgtgcgatt ggtaaacgac caatcgattt gcatttaaaa ggatttcaag ctttaggagc
      901 aaaaattatt caaaaaaacg gctatatcga agcaattgcg gatgaattga tcggtaacac
      961 gatttattta gatttcccta gtgtaggtgc tactcaaaat atcatgatgg ctgccgtaaa
     1021 agcaaaagga acaaccatca ttgaaaacgt agctcgcgaa ccagaaatcg ttgatttagc
     1081 aaacattttg aataaaatgg gcgctcaagt ctatggagct ggtactgaaa caatgcgtat
     1141 tgaaggcgtg gatcatttac atgcagtcaa ccactcaatc gtacaagatc gtatcgaagc
     1201 aggtaccttt atggttgctg ctgcaatgac acaaggcaat gtgctgattg cagatgctat
     1261 ctctgaacat aaccgcccat tgatttctaa attgatcgaa atgggtgcag aaatcattga
     1321 agaagaaggc ggagtccgtg tcatcggacc aaaacatatc ttacctacag atgtaaaaac
     1381 gatgcctcat cctggtttcc ctacagatat gcaagctcaa atgacagcta tccaattagt
     1441 tgcagaaggt acaagtgtag tgactgaaac agtgtttgaa aatcgtttcc aacatttaga
     1501 agagatgcgc cgtatgaacg ctcatgtcaa aatcgacgga aatgtagcaa tcatggatgg
     1561 aaaccatgaa ttgcaaggtg cagaagtata tgcaacagac ttgcgggcag cagcagcatt
     1621 agttttagct ggcttgaaag caaatggaat cacacgtgtg cgtaacttga attatctaga
     1681 ccgtggatat tataatttcc atatcaaact acagcaatta ggtgcagacg ttgaacgtgt
     1741 agacatggat caaacttctg ctgaaaaaac agcacaaacg attgcttaag gaagtggctg
     1801 aatgagtaac caacgatata tcttattaac tttgataaag attttaatgg tgatcttatt
     1861 gcttatcctt ctttttgtgg ccggaacgat gatcggatat ggtgtcatcg gtggcggcaa
     1921 tccatttaaa gtatttcagc caagtttgtg gattcatatt cgagactttt ttcattgata
     1981 aataagaatc acagtggttc tagtcgatat gaagtgagcc atgaagcaga acatgataaa
     2041 agaaaacaga agggaacgtt gacgttagtc gcgatccctt tttttagtaa aagaaaagaa
     2101 ggaatctaat tgatgaagaa gatattgatt tatttagtta gaggatatca gcgctttatt
     2161 tcgcctgcat ttccacctag ctgccgttat tacccaacct gttccaatta tatgataaaa
     2221 gcaattcaaa cccatggcgc gctaaaaggg acggtaatgg ggactgcacg gatcttacgc
     2281 tgtcatcctt ttgtcaaagg cggtatcgat tatgtaccat tgacattccg attaacgcga
     2341 aataagaaag ataaaaaaga accagattat aaaaaggttg tgaaaaatac gggtagcact
     2401 gagcgataaa gaaacaattt ggaaaatagc ttcttatatt ttgcaaaatt gtgagttatt
     2461 gccgaagtgt tggattttga acaccgtcaa aaaaaaggtt gtgaaaaata cggctagcac
     2521 tgagcgataa agaaaaagag gaaatttatt gtcaaagtaa caactccgca actacttata
     2581 tgggggacaa aaaatgatcg aagaactaaa caagaaagat ttaccatggt ccttgttatt
     2641 agatgcagat cctgataaag aaaaagttca agtatatgtt tccagaggga gtggctggat
     2701 atggaaagaa aaagaaaaaa caataggtgt actgatctat gtggcaaggg aaaaagaata
     2761 cgaaatcgtc aatgtagcag taaccccaac gtatcaagga aaggggattg gcggaaaatt
     2821 acttgagaca gcttttcaga agctttcaca actcgcttcc agtcaaactc agatcatcat
     2881 acgaaccggc agtactagca gtgcggcgtt acatctctat caaaaaatgg gctatgtgga
     2941 gattggtcga gtcaaagact attttatcca tcattactct gagcccattt ttgaaaatgg
     3001 agatcaatta agggatcaag tgattttagc aattcactta cctaaaaata gctttaacta
     3061 ataaaatttc aattcaagaa aatgctttca aatgctaaat agatacatta caatagcttt
     3121 agcaaacaaa aaggagaata tttttatggg aatattagtt tttgattttg gtggatcggc
     3181 tgtcaaatat ggttgttggg atggcaaaga gattaaaggt aagggacaat ttgcaacgcc
     3241 tgaatcttgg gaagaaatga aagcgcaatt atttcaagtt tataaaaaaa tactcgtttc
     3301 ttttgaagtc gaaggaattg gaatcagctc tcctggagta gtgaataatg agaaacaggt
     3361 gattgaggga atcagtgcga ttccttatat tcatggattt aatattttcc gagatttgga
     3421 aactctgttt caacttccag taacgattga aaatgacgcc aactgtgccg gaatggctga
     3481 attttatgaa ggtgctgccc gcgattatca agatgttgct tttgttgtgg caggaactgg
     3541 gattggcggg gcgttgttca cgaaaggaca aatcaataaa ggggcacatc tttacggtgg
     3601 agaatttggg ttgatgttct taaatggcga taagacattc agtaaacttg gtacagcggt
     3661 acagatggct tggcgttatt gtgaacgcaa aggtctcgat aaaaatgctt ataccggaaa
     3721 agatgtcttt gaattagcag aaactggaga tgcaatagca aaagaagaag ttgagagttt
     3781 ttatacgtat cttacaaagg gattattcag tattcaattt tcgtttgatc cagaagtgat
     3841 cgtattaggc ggcggggttt ctgcaaaaga agggctcatt gatgagatca aaagccgaat
     3901 gaagaagctg acagaacaat tcgatctgca tgatttcgaa ccgcagattt tattatgtga
     3961 atacagaaac gatgctaatc ttgtaggtgc agcagcaaac tatctcgctg tacgtcaagg
     4021 ggagaattaa gagctttaga gaaggtgcag cttgcataaa agaagtgaat gaaatgaata
     4081 ggagattttt acctaaggaa tgttttattt gctgcagtat gataaaatat ctgagaggtg
     4141 aaaatgatgt caaaaaaaaa taaagatatt gaagtgcgta tagaagaagt gaaaaaagat
     4201 atcaaaggta agaattatga agtcactcag ttatttatag ggaaaaaaat gattggtgag
     4261 atcttagcct atggaccaaa agaatatgaa attttctttg gtgaagaaga ttttggaaaa
     4321 gaaaaaagtc ttgaaaatgc gatagaaaca gtgattcgac actggaatct gcacgaataa
     4381 aaaaatatca aaaaaacttt caataaaggg ttgcaaaaat ctggaaaatt aggtattata
     4441 actaagtcag gttgatacaa acctttcgga ggagtagcga agtggctaaa cgcgacggac
     4501 tgtaaatccg ttccttaggg ttcagtggtt cgaatccact ctcctccatt tcattggggt
     4561 atagccaagc ggtaaggcaa gggactttga ctccctcatg cgttggttcg aatccagcta
     4621 ccccagtata ccacaatcgt aagctctcgt tagttcgaga gctctttttt ttgctttgct
     4681 accttgttcc ttgaagattc tgctgattta agatagagtt aagttaacta caagaattgg
     4741 agggatccac atgaaatgga aagaaaaagt agacgaagca gctgaaaagt tatatgattt
     4801 ggtcaaatca gaaaaataca atattgaagt gaatattccg aaaaaaggcg gaaaagcggt
     4861 ccgggtaaaa tcaaaacgcc caacgaatca tacaaaaaaa tggatggcta aaaaccgcta
     4921 ataataacaa aagatccata agtcggcatt ttcatcgatt ttagggtctt ttgttatttt
     4981 ctaggttgga catatctaaa aaattgtttc tgacaatagg agtaggaaga acgatgtgtg
     5041 tctaaatcct ctgttgatgg atagaaacct ttatcttttt cagttgtgaa tcaggtatat
     5101 accagttata atagaagaaa cgaaaggacg ggtgtacgtt atgtcgaatc aattacctgt
     5161 atatatacag attcatgacc aattaaaaaa tgaaatcgaa caaggtatat ggaaagtcgg
     5221 agaccgtctt ccttcagaaa gagaattagc agtgaaattc aatgtcagcc gtatgacgtt
     5281 gagacaagca attcaaaact tggcagatga aggaatctta gaaagaaaga tcggttcggg
     5341 tacatatgtt gcacgagaaa aagtacaaga aaaaatgtct ggtgcaacaa gttttacaga
     5401 aattatggaa tcacaaaatc gagtaccgtc tagtcggaca atctcttatt tcttgacttc
     5461 gccaagctca agtgaaatgg aaaaactaaa cttgagtaaa gatgacacga tcttgcgaat
     5521 ggaacgtatt cgtttcgcag atgatgtccc tatttgtttt gaagttgcca gtgtgccaca
     5581 aaagctgatc gatggctaca gcaaagcaga gattactgaa tcgttgtatc gcacgctaga
     5641 agaaaaaggc gggaaaaaga tcggtccagc gaatcaaacg attactgctg tgttggcttc
     5701 tgagaaaatt gctgactatt tagaggtaaa acgaggagat gcagttcttc gtttgcgcca
     5761 gatttcttat tttgaagacg gtacgccgtt tgagtatgtg cgtacgcaat acgtaggaaa
     5821 tcgttttgag ttttatttgg aaaaataaaa aacaggtgat ccctgattcc gtattagaaa
     5881 taaaagagaa tcagaatcac ctgtttttat atatgatcag ttaccagttg ctcgtgataa
     5941 gaaacaggac cctcttcaaa ttggacttgt ccgttcagca gctcaatgat ggattcttta
     6001 aagtggtcag cacttttttc atctacagca cagatgacgc taacttgatc agtatattgg
     6061 atttctttta taaaaaaatg ttggagttca agataattct gtaattttcc tagttgcgga
     6121 tacgtgatca tcacagagat ctcctgttgc aaggtacctt ctacgattcc aatgtcagac
     6181 aatgcttgag agaccgcatg agtgtatgct cgtattaatc cgcctgtgcc gagtttcgtt
     6241 cctccaaaat atcgagtgac tactgcagct acattgatca gttgattttt tttgaggact
     6301 tccaacatcg gtatgcccgc cgttccactt ggttctccat catcgctgct tcgctggatt
     6361 tcattttttt ctccaatgat gaaggcgctg cagttatggt tcgctttcca atgttctttt
     6421 tttatttctt gaatgaaact ttttgcttcg tcctctgatt ctattcgtct aagagaacag
     6481 ataaagcgtg attttttgat ctcgatctca ctttgtccat tttcttttat tgtacgatag
     6541 cgctcgatca tcttgtcacc tcttttttca ttttctttat tcagtataaa taaagttcta
     6601 ggttgtttca acactgtaac ggttgcgcaa ttgctgtagt atgcgataat aaagacaaag
     6661 gcaggtggat ctggggatgc aggaacgaat gaaaaagtac gatgcaatta cgcattattt
     6721 gaagaacaat ggcggctctc aagtaacgtt gacctttacc caatttgacg aactgctgtt
     6781 tcccagtaac ggacttccca aaacagcaag ggaaagtaca gattggtggg caaatgatta
     6841 taaacaccct gaaaaaggtg cctatggctg gataaatgca ggctatgaag tagttgtcat
     6901 caatttggac aaagaatatg tcgtgttcaa taaattagtg aaatctagtt ggctatttga
     6961 ttaaataaac cgcgtttaga aaacgttgac aaatttcttt ctttttatat aatagagtaa
     7021 cagacgcgaa gaaaacgttt gcgtagtttg ttttaaaaag gagagaaaag tatggctaaa
     7081 aaaacaatca tgcttgtatg ttcggctggt atgagcacaa gtttactagt aacaaaaatg
     7141 caaaaagctg ctgaagcaaa aggaatcgac tctgatattt tcgctgtgtc cgcttctgac
     7201 gcagataaca atcttgcaaa taaagacgtg gatgtgttgt tattaggccc acaagttcgc
     7261 tttatgaaag ctgattttga gaaacgtctg gaaccaaaag gcattccttt agatgtcatc
     7321 aatatggctg attatggtat gatgaatggc gaaaaagtgt tagatcaagc aatcacgctc
     7381 ataggtgaat aaatagaaca gtataactat cgaacaagcg atccaaaaaa tagatcgctt
     7441 gttttttcgt atattttttt agggcgaata atatgaatca tttttggggt agaaggcttc
     7501 tgacgagaga tattaaagca atagactgtg aggaggtaaa tttaccaaat tatgagaaga
     7561 tcgcagcagt ggaacgtttg agcaactgga ttctttgtca tcgctgtgga atgagaacgt
     7621 ccgtcattga tggacagctt gcagattacg gttatttttg tacacattgt ctatatttag
     7681 ggcgatgcga cactcaacaa gatttatatt tgtttgatca gcctgaagca aaacctcgag
     7741 aagtcgtctt tttttggaca ggacagctta ctgaaaaaca aacggaaatc tcaaagagaa
     7801 tactttgcca ttcagaaaaa agacatcatc ttatttgggc tgtaacaggt gcagggaaaa
     7861 cagagatgct ttatcctatt ttagtggaaa ctttaaaagc tggaggaaga gtagcgattt
     7921 gtacaccgcg agtcgatgtt tgtaatgaat tgtttttacg ctatcgttat gtttttccag
     7981 aagaaaaaat cacgttgctc catgggaata cagcaacggc ttataccttt acttcttttg
     8041 ttatctgtac gattcatcag ctataccgtt tttatcggtc ctttgattta atagtgatcg
     8101 atgagatcga tgcgtttcct tataacgggg atgcaggatt agctcatgct gtgcaaacag
     8161 cgattaaacc agacggacga ttcatctact taagtgccac acctgataaa aagttactaa
     8221 aggagatcaa gcagacgttt gacatccaca aacttgcttt acgctttcat cggcgtttgc
     8281 ttcctgaacc cgtcttggtt ttcatgaata attggcgaca aaaatgcaag aacaagaaga
     8341 agataaaatc tttggtgcgg atcattcatc aattaattaa agaaaaccat atccttttat
     8401 tttgtccaag tatcacgatg atgcatcgtt tgaaagccac acttcaagag gctcttccga
     8461 gatatgagat cacagatgtt tcttcaagag acaatcagcg ggcggaaaaa gtccagaaaa
     8521 tgcgagaagc aaaatatgac atactgttaa ccacgatgat ccttgaacgt ggagtcacat
     8581 ttgaaagaat atccgttatc gttttaggag cggatcatcc ggtttttact aaatcttctt
     8641 tggtacaaat cgcaggaaga gccgatcgta aagggcctta tacgaacagt caagtatatt
     8701 ttttctatga agaaaaaact gcagctattc gaaaagcttg tcaggaaatc aaagaaatga
     8761 atgaagaagg gaagaagata ctgtgaggtg cagttgctgc agtaaagata tcgtccaaaa
     8821 tttaacattc agcgagatta ttggtgtttc gaaatacaga ttacctcaga cttgttcagt
     8881 ttgtcgcgca caatttcatt tattggaaac aagaggctgt tctggctgtc aaaaaccaat
     8941 ccatttcaat ctagagagta cgaaaaagaa agtaaattct atccccgttt actgcagtga
     9001 ctgtcaagaa tggaagaaga aatatccgac ctatgatttt cagcaccgtg ccttttttgt
     9061 gtacgatgaa aatatgaagg cctggctcaa tcaatacaag tttatgggag atatccgact
     9121 agcaggcacc tttgcatata aatggacgca gataaaaaaa gaatacccga catacatcta
     9181 ttgtccaata cctttatctg aaaaaaggcg aacagaaaga ggattcaatc aagtaagcga
     9241 gatgttgaaa gcagcaagaa ttccttttca gatgctactc aaaagagaga agcatctgct
     9301 ggctcaagca aaaaacacgc gaaaggaaag attggagatg cctcaacctt ttgaacttgc
     9361 agtcaccttt tctaagatac aaaataaaaa aatattgatt attgatgatg tctatacaac
     9421 aggacagact cttttccacg cagcagattg tttgcagatc gcacagccga aaatcatccg
     9481 aactatttct ttggcgagat gaattagatg tggaaatttg atagcgattt aatttgcaaa
     9541 taacctagag ttcgatataa tagaattaag aagagggaaa gagtggtcct tctccttctt
     9601 gattgtggta gacgaaaggg gtaattttta tgtttagata taatgtacgc ggcgaaaata
     9661 tcgaagtaac tgaagcgatt cgcgactacg ttgagaaaaa agtaggcaaa ctagaacgct
     9721 atttcagtga cgcacccgat gcaacggcgc atgtgaactt aaaagtttat acagaaaaaa
     9781 cagcaaaagt ggaagtaacg atcccattac cttatcttgt attacgtgcc gaagaaactt
     9841 ctccagattt atacgcaagt atcgatttgg ttgttgacaa attggaacgc caaatccgca
     9901 aattcaaaac aaaaattaat cgtaaatccc gtgaaacggg catgaatact gcaaatgctg
     9961 ctgctttatt caatgaagag gacgaaaacg aaaatgattc tgaattagat atcgtacgta
    10021 cgaaacgcct ttcattgaaa ccaatggata gtgaagaagc agtcttgcaa atgaacatgc
    10081 tgggacataa cttctttatt tttgaagatg cagaaacaaa tggtacaagt atcgtttacc
    10141 gccgtaaaga tggaaaatac ggactgattg aaacagactg atcagcctta cttaaataac
    10201 aacgaaaact tgcagcagct actgacagct gccgcaagtt tttttgagtt tcctcctctt
    10261 ttagatgaaa tatgaataaa ttatgaagtt cttactttaa tacgcttaag atatttcaat
    10321 tatctataac taatgataaa atgaaaagta aagtctacat agtctggata atacacagaa
    10381 ggaaaaggag attacacaac gcatggccaa tttgattcgt tcacttatcg aaaacgataa
    10441 gaaagaacta aaacgtttag atagcattgc aaaaaaagtt gaagcatacg ctgaccaaat
    10501 ggcagcatta actgatgaac aattacaggc aaaaactgct gaattcaagg gcagatacca
    10561 aaaaggagaa acattagatc aattacttcc ggaagctttt gcagtcgtcc gagaagcagc
    10621 aaaacgtgta ttaggtttat atccatacca cgtacaattg atgggtggaa tcgtgcttca
    10681 cgatggaaat atccctgaaa tgcgtactgg tgaaggtaaa accttgaccg caacgatgcc
    10741 agtatatcta aatgctctga ctggcgaagg ggtacacgta gttaccgtca atgaatattt
    10801 agcaacccgt gactcgacgg aaatgggcga actttataat ttcttaggat taacagtggg
    10861 gttgaatatc aactcaaaat cttcggatga aaaacgcgag gcttataatt gtgatatcac
    10921 ttatagtacg aataatgaat taggatttga ctacttgaga gacaatatgg tcgtttaccg
    10981 ccatcaaatg gtacaacgtc cgctgaatta tgccattgtc gatgaagttg actcaatctt
    11041 gattgatgaa gcgagaacgc cgctgatcat ttcagggcaa gcagaaaaat ccacagcttt
    11101 atatacaaga gcagacaact tcgtgaaacg tttgaaagaa gaagaagatt ataaaatcga
    11161 tgtacaatca aaaacaatca gtttaaccga agcagggatc gaaaaagcag aagaaacatt
    11221 cggtttggat aacttatacg acattgaaaa tactgcattg acccatcact tggatcaagc
    11281 attgagagcc aactatatca tgcttttaga tatcgattat gttgtccaag acggaaaagt
    11341 actgattgtt gaccagttca ctggtcggat catggatgga cgccgttatt cagatggact
    11401 tcaccaagca atcgaagcta aagaaggcgt agagatcgaa gacgaaacga aaaccatggc
    11461 gacgatcact ttccagaact atttccgtat gtacaagaaa cttgcgggaa tgactggtac
    11521 agctaaaaca gaagaagaag aattcagaga aatttataac atccaagtat accagattcc
    11581 gacaaatcgt ccggttatcc gtgatgatcg tccagatttg ctttacccaa cattacaaag
    11641 caagttccac gctgtcgtgc aagatatcaa agatcgctac cgcaaaggtc aacctgtgtt
    11701 agtcggaact gttgcggttg aaacatctga gttattatca gatatgctga atcaagaacg
    11761 tattcctcat gaagtgctga atgcgaaaaa tcactttaaa gaagcagaga tcatcatgaa
    11821 tgctggtcaa aaaggtgctg tgacgattgc taccaacatg gctggtcggg gaacagatat
    11881 caagttagga cttggggtaa gagaacttgg tggtctagca gttatcggga cagaacgaca
    11941 tgaatctcgt cgtatcgata accagcttcg aggacgtgca ggacgtcaag gagaccctgg
    12001 tatgtcacag ttctacttgt cattggaaga tgatttgatg aaacgattcg gttcagaacg
    12061 aatcaaagct ttcttagatc ggatgaagat cggtgaggaa gatgctgtta tccaaagcaa
    12121 gatgctgacg aaacaagtag aatctgcaca aaaacgtgta gaaggaaata actatgacac
    12181 acgtaaaaac gtcttacaat acgatgatgt gatgcgtgaa caacgtgaag taatctataa
    12241 acagcgacaa gaagtaatca tggaagaaaa aagcttatcc aagccactaa tgaacatggt
    12301 caaacggaca atcagtcgtg tagtagatgc gcatacacaa ttagagaaag aaaactggaa
    12361 tttggaaagt atcatcgatt ttgccggcag tactcttgtc catgaagata gtattactct
    12421 tgcagatatc gaaggaaaaa cagctcagga gatcaaagag tatctaaacg aacgagcaca
    12481 agaagtattt aataccaaag cggctcaact aaatggtcca gagcaactgt tggaatttga
    12541 aaaagtcgtg atcttgcgtg ttgtggactc taaatggaca gaccatattg acgcaatgga
    12601 tcaattacgt cagtcaatcg gcttacgtgc ttatggacag aacaatccat tagtcgaata
    12661 tcaaacagaa ggctataaga tgtttgaaga tatggtaggc gccatcgagt atgaagtcac
    12721 tcgaatcttt atgaaagctg agatccgtca aaacgtacag cgtgaacagg tttctcaagg
    12781 aacagcttct cactcagaag acggagatgc caaagaaaat agtaatacta gcgcgaaaaa
    12841 acagccaatc catgtgaaca aggtcggaag aaatgatcct tgtccttgtg gaagcgggaa
    12901 aaaatataag aactgtcatg gaaaaaatgc aaactaattt ctgacagcag gattggtgag
    12961 acaaattctt tttttaagaa ttcgtctcac cttctttctg ttatttgctg attctgttag
    13021 actagatata atgaaaaaag tatagtgaaa gaaggaaaaa acatggaaat atccgaaatt
    13081 cgaaatctcc tgacagaaat gcaggaaaag gtcacaagtt tcaggaggtc tctttgactt
    13141 agatcagctg gaagaagaca tcgcggaagc agaagcaaaa atggctgaac ctggtttttg
    13201 ggatgacagc gaagccgcac aaaaagtgat cagtgaaaat aacgctaata aagaaaccta
    13261 tgaccaattc cattctcttg ccgaagaact agaagaaatc gaattgatgg tggagatgct
    13321 gcaagaagaa cctgatgcag caatgcaaga agaagcagaa acacgtatca atgcattaga
    13381 tgaaaaaatg aagacgtatg aattatctat gctgttagac ggaccttatg atcgaaacaa
    13441 tgcgatcgtc gaattgcatc caggggctgg cggaacggag tcccaagact ggggcagcat
    13501 gcttttacgt atgtatacac gttgggcaga gcagcatggc tatcaagtag aaacactaga
    13561 ttatcaagca ggtgatgaag cagggatcaa gagtgtgacc ctgctgatta aaggacataa
    13621 cgcttttggt tatctaaaat cagaaaaagg tgttcatcgc cttgtacgga tttcgccttt
    13681 tgactcagcg aaacgacgtc atacttcttt ttgttcggta gatgtgatgc cagagcttga
    13741 tgaaacgatc gatatagaaa tcaatccaga tgatttgaaa atcgatacgt accgagcaag
    13801 tggtgcaggt ggtcagcaca tcaataaaac agaatctgct gtacggatca ctcacttgcc
    13861 tacaggaaca gtagtagcta gtcaggcaca acgctcacaa ttgaaaaacc gtgagcaagc
    13921 gatggggatg ttaaaagcta agctttatca attagaagtg gaaaagaaag aacaagaagc
    13981 agctgcactt cgaggagaac aaaaagaaat cggctggggt tcacagatcc gttcttatgt
    14041 tttccatccc tattctatgg taaaagacca tcggacaaac gtagagacag gaaatgtcca
    14101 agcagttatg gacggtgacc ttgatttatt tattgacggc tatttaaaaa tgcatctaca
    14161 ataagaaccc attgttaaat tgaaataaaa ttgtaagatt ttgcaagcat gttgaaacat
    14221 tgccatgcta taatagctaa agactgaaaa agatatggag agaacgccat gattgaaatg
    14281 aaggatgtaa tgaagaagta ctcaaatggt acgaccgcta tccgcaatct ctcgattgtc
    14341 atcgaacaag gagagtttgt ctatgtggtt ggtccgtctg gagccggtaa atctacattc
    14401 atcaaattga tgtatcgaga agaaaaagct tcaaaaggaa ctttgaacgt cgcaggtcat
    14461 gatctaatag caatcaaaaa ccgcgaagtt ccttatctac gcagagaaat cggcgtggtg
    14521 ttccaagact ataaattatt accaagaaaa acagtatatg aaaatgttgc gtacgctatg
    14581 caagttatcg gcagaaaacc tcgagatatc aaaaaacgag taatggaagt gctggacctt
    14641 gttggtttga aacacaaagt tcgagtcttt cctagcgaat tatccggtgg ggaacagcaa
    14701 cgtgtctcta ttgctcgggc aatcgtgaat acgcctaaag tacttatcgc ggatgaaccg
    14761 acaggaaatc tggatccaga aaactcatgg gaaatcatga aattattaga tcggatcaat
    14821 gcccaaggaa ctactgtcgt gatggctaca cataacagta cgatcgtaaa tacgattcgg
    14881 caccgagtaa ttgctatcga aaacggccgc attattcgag atcaagcgga aggggaatat
    14941 ggatacgatg attagaacct ttttccgcca tttattagaa agtatcaaga gtttgaaacg
    15001 taacggctgg atgacagttg cttcagtcag tgcggtaacg atcacgttga ctttagtcgg
    15061 tgtattcatg gcagttatca tgaatgcaac taaattagct caggatatag aaggaaacgt
    15121 tgatgtatct gtattcgtag atatcggtac aaaagacgaa gagatgaaaa agctagaaaa
    15181 agaattgaat gacttagatc atgttaaaaa agttgaattt tcaagtaaag aacaggaatt
    15241 gaaaaaaatc caaaacgaaa tgggtgattc ctggaaattg tttgaaggtg acaataaccc
    15301 gttatatgat gtgtatgtag taagtgctac tgatccttct tatacaaaac aagtagcaga
    15361 agaagcagca gatttgaaga atgtttctcg ttctgattac ggtggagctt cctcagatcg
    15421 gattttccaa atcgctggtg cagttcggac atggggatta gttgcagcgg cattgctgct
    15481 gttcgtagcg atgtttctca tttcgaacac gattcggatc acgattttgt ctagacagcg
    15541 tgaaattcaa atcatgcgtt tagtcggtgc aaaaaatgga tatattcgct ggccgttttt
    15601 ccttgaaggt ggctggatcg gtctgatcgg tgcgattctt ccgattttga tcatcacatt
    15661 tggttatgca tggtttttcc aattgatcaa tccatcatta ttacgttccc attattcatt
    15721 gattcatcca caaaatatcg tttggaaaat caatctttta atggtcggca ttggtgtgat
    15781 cattggttca cttggctcga tcatttctat gagacgtttc ttgaaattct aataccacaa
    15841 tataaataaa atgagaaagt tggacagttt cgttccagct ttcttttttt attggctagg
    15901 agaatagaag gaagcggctt ttttcccttt actttaaaaa acaacttggg tattcttaag
    15961 ttggtagagg aagaggtgaa gccgtgaaaa ttatcgttga caattttttt acgatccttt
    16021 tgattatgaa tattttgctt tcctttatca tcgtttttcg agaaagaaag gaaactgctc
    16081 aaacatgggc atggctgctc gttttgatgt tcattccagt tgtaggattt attttatata
    16141 tttttttagg aagagggatt tccaaagaga aaatctttga tttgaagatc caagggaaaa
    16201 tcggtaagaa cctggaaatt gaagaagaca aacaggcatt gatgcgaggg ctttatcctc
    16261 atccgcctac tggacaagta gatgtgaaac aattgatcta tatgctcacg gtatttgaaa
    16321 gtacgctcta tacgactaaa aatgaaatca ctttatttac agatggtcgt gaaaaattcg
    16381 atgcgctgat tgaagatatc aagcaagcag aagaccatat ccacttccag tattatattt
    16441 atcgcagtga tgcattaggt gaagaagttc gagatgcatt gacagaggcg gcaagacgag
    16501 gggtaaaagt cagagtcctt cttgatgcat ggggttccac acaagtttct tccagctttt
    16561 ttcagaattt gaaaaaagca ggcggagaaa tcgcattttt ctttcctcta tttgttccgt
    16621 atattaatcc tcggatcaat tatcgcaatc atcgtaaaat cgtagttatt gatgggaaaa
    16681 tcggatatac aggtgggttc aatgttggaa atgaatatct aggattggta aagaaatttg
    16741 gttattggcg agacaatcat ttgcgtattt acggagaagc ggtgtatatc ttgcaaaacc
    16801 gttttttgat ggactggaat tctcagcata caaaagaagt aggctattct cccaaatttt
    16861 ttccgtccat tcactctact ggtgatatag ctgttcaaat cgtgacaagc ggaccagata
    16921 ccgaacatga acaaatcaaa atgacttatt tgaaaatgat ttcgttagcc aaacgggaga
    16981 tattgatcca aacgccttat tacataccgg atggatcgat tcatgaagca ctgaagttgg
    17041 ctcttctttc aggcgtaaaa gttcatatcc aaatacctaa caaaccagat catcttctcg
    17101 tttactgggc aacgtattct ttcgctgcag agctgatcga gtatggagca aggatcgaaa
    17161 catatgagaa tggatttatt catgcaaaga cgatgattat cgatggtggc attgtttcag
    17221 ttggctcagc aaatatcgat gttcgttcat ttcgcttgga ctttgaggtc aatacactga
    17281 tttatgatga acgaatggct tcacgtgtaa gaaaagcatt ttttgaagac tcgaaaattt
    17341 ctacgcatct cacaaaagaa atgtatgaaa accgaggaat aatcatcaag atgaaagaag
    17401 gattagcaag attgatttcg ccgctccttt aaaacacaaa aaggacatga gaaccatcaa
    17461 cagatggaga tctcgtgtcc ttttctaacg gggccatttc tgagagtacg tcagaaatgg
    17521 agaaagcgtc tcgcatgagc gaaattaact ttggggtatc tcttgttttt tggggaaagc
    17581 aagaaataag ctaatatatg ctattaaaag agacacattt caaagccagt atagcataga
    17641 aacttttaat gagatagttt tttttacaat tatgaggatt tattttgtta tttaatgatt
    17701 ttgattcgtt ttcatcaagt aatgaaaatg ataaaataaa catactttag gattaaagga
    17761 gatttctaat gaaaaaactt aaattattct taccaataat aggattagct attcttttat
    17821 caggctgttc aaagtggatt gatcgaggag aatccattac ggctgttggc tcttctgctt
    17881 tacagccttt agtagaaaca gttgctgaaa cttaccagac agaaaatcct ggaaaattca
    17941 tcaatgtaca agggggcgga agcggaactg gtttgtctca agtacagtca ggagcagtcg
    18001 acatcggaaa ctctgatttg tttgcggaag aaaaatcggg gatcgatgcc tcagcattag
    18061 tcgatcatcg agtagcagtt gttgggatca ctcctattgt gaacaaggat attggcgtaa
    18121 aagacatcag tatggaaaac ctgaaaaaac tatttacagg cgagatcaaa aactggagtg
    18181 aagtcggtgg aaaagatcag ccagtagtta tattgaaccg tgcttcagga agcggaaccc
    18241 gtagcacgtt tgaaaaatgg gtattggacg gagaaacagc tgttcaggca caagaacaag
    18301 attcaagcgg aatggtgcgc cagatcgttg ccgacacacc cggtgcaatc agctatgttg
    18361 ctttttctta tgtttccgat gatgtagata cgttgaatgt taacggtgta gaaccgacag
    18421 atgaaaatgt gacaacgaac aaatggacga tttgggcata tgagcatatg tacacaagag
    18481 atcatccaaa aaaactgaca aaagaatttt tagactatat cttatctgat gaagtacaag
    18541 ataacatcgt tggagaacta ggttatatcc ctgtttctca tatgaaagtc gaacgtgatt
    18601 ggcaaggaaa tatcgttaaa gagtaatctt tacacaaaat ttacaaactt agctaaactt
    18661 ttacatgtta ttaaaaccaa attgatgttc aatttgtaca ctgagtgagt atgttaaacc
    18721 tgattaaggg ggagtcatct gtggaagatg tgaaaaaagt attattaaca aaatcaaaac
    18781 gttcaaaaat ggaacagcgt ggaaaattca tcagtttttt atgtatcgcg ctgatcgtgt
    18841 tggttgtatt atctattttt tattttgtag ctagtaaagg attggccacc ttttttactg
    18901 ataagatcaa tgtatttgat tttctgtttg gtacagattg gaatccaagc caaatcggag
    18961 caaatgggaa accaatggta ggggcattgc ctatgatcac aggttcgttt attgtgacct
    19021 ttttatctgc tattgttgcc acaccatttg ccattggtgc agcagtattc atgacggaga
    19081 tctctcctaa aaacggaacg aagatcttac agccggtcat cgagctgctt gtaggtattc
    19141 cttctgtcgt ttatggtttt atcggtttat cagttatcgt gccttttgtc agaagtattt
    19201 ttggcgggac agggtttggt atcttagctg gtacatttgt gttgttcgtt atgatcttgc
    19261 cgactgtcac aacgatgact gttgatgcat taaaggcagt accacggcac tatcgggaag
    19321 cttcattagc gcttggtgcc acaagatggc aaacaatcta caaagtcgtg ctacgagcag
    19381 ccgtgcccgg gattttaaca gcagtcgttt ttggtatggc tcgtgcgttt ggtgaagcct
    19441 tagctatcca aatggtcatc ggtaatgcag cattgatgcc aacaggactt actactcctg
    19501 cttctacatt gacgtccatc ttaacaatgg gaatcggaaa tacaatcatg ggaacagttg
    19561 aaaataatgt gttatggtca ttagcgctga tcttgctatt gatgtcatta ttctttaata
    19621 tcgtgatccg tatgattggg aagaaaggag agctgaaata atgaacgcaa aacgctcaga
    19681 taaaattgct acaggtgttt tatatgtagt ttcggggatc atcgtattga ttttagcagc
    19741 tttactactt tatatcttag ttcggggaat accgcacatt tcatggtcct tcttgaccga
    19801 accttccaaa gcctaccaag aaggcggtgg aatcgggatc cagctattta actcgattta
    19861 tttgcttttg atcacgatga tcatcagttt tcctatttct ttaggtgcgg gtatctatct
    19921 ttcagaatat gctggaaaaa actggctgac agatgtgatt cgcacgtcga ttgaaatctt
    19981 gagctcattg ccttctgtcg ttgtcggttt attcggtttc ttggttttcg ttattcaatt
    20041 ccagtatggt ttctcgatta tttctggtgc attggctttg actgtattca acttgcctct
    20101 tttgactaga acagttgagg agtctttaca agcggtccat tacacacaac gagaagcagg
    20161 attggcttta ggtttgtcac gctgggaaac agtgataaaa gtggtggttc cagaagcgac
    20221 accagggatt ttgactggtg tgatcctaag ttctggaaga atttttggtg aagcagctgc
    20281 attgatctat acggctggac aaagtgcacc tgcgttagat tttacgaact ggaatccatt
    20341 aagtgtttca agcccgatca gcattttccg tcaagctgaa acattagctg tccatatttg
    20401 gaagatcaat acagaaggca cgatgcctga tggtgtttct gtttcggctg gcgcttctgc
    20461 agtgttgatc attgctgttt tactgttcaa cttcggcgct cgtgcgattg gcaaacgatt
    20521 ataccgaaaa atgacttcag cctaaggaga agaagcaaaa tgaaaaaata taactggaat
    20581 gaaacaaatg tcatcaccat gccaaaagag aaagaagtag cactatatac ggatgatcta
    20641 catgtctggt atggcgacaa tgaagcaatc aaaggagtgg atctggaatt tgaaaaaaat
    20701 aagatcactg cactgattgg tccttccggc tgcggaaaat ctacgtatct tcgttcgttg
    20761 aatcgaatga atgatgggat cgctaatacg aaaatcactg ggaaaatcat gtatcaaggc
    20821 gtagatatta atgcgcctca agtggatgtt tatgagatgc gcaaacggat tggcatggtt
    20881 tttcaacgtc ctaatccgtt cagcaagtcg atttatgaca atattacatt tgctttgaaa
    20941 cagcacggcg aaaaaaacaa aaagaaatta gatgaaatcg ttgaaacaag cttgaaacaa
    21001 gctgccttgt gggaccaagt aaaagacagc ttggacaaaa gtgccttggc tttatctggc
    21061 gggcaacagc aacgtttatg tattgctcgt gcgatcgcga tgaaacctga tatcttgctg
    21121 ctagacgagc cggcaagtgc tttggaccct atttcgacag gaacggttga agaaacactt
    21181 gtaaacttga aagaagacta tacgatcatc atcgtgacgc ataacatgca acaagcggct
    21241 cgtatcagcg actatactgc ctttttctat ctaggaaaag taatggaata tgacaaaact
    21301 aacaagatat ttaccagacc aaaaattcag gcaaccgaag attatgtgtc cggtcatttt
    21361 ggttaagacg gaggcctcaa catgacaaaa gaaattattt catctaaaga tcttcatctg
    21421 tattatggaa agaaagaagc actaaaaggg atcgatctaa gtttcaatca aggggaaatc
    21481 actgcgatga tcggtccttc tggttgcggg aaatccactt atctgcgttc tttgaaccgg
    21541 atgaatgacc tgattccgaa tgtaacgatc accgggagtg ttttatataa agacaaagac
    21601 atctatggtc caaaaacaga tgttgttgaa ctaagaaaag aaatcggcat ggtattccag
    21661 cagccaaacc catttccttt ttctatctat gaaaatgtca tctatggatt gaaattaaaa
    21721 ggggaaaaag ataaaaaagt ccttgatcaa gtagttgaag aaagcctgaa ggcagcgtct
    21781 gtttgggatg atgtgaaaga caaattgcat aaaagtgctt tatctttatc cggtgggcag
    21841 cagcagcgtg tatgtatcgc acgtgttttg gcagttaatc cggaaatcat cttattggat
    21901 gaaccaacaa gtgcgcttga tcctgtttct actgggaaaa tcgaaagtat gctgttagaa
    21961 ttaagagagc ggtatacgat gatcatcgtg acccataata tgtctcaagc ttcacgtatt
    22021 tcagataaga cggcattctt tttagatggt cacttgatcg aatacaatga tacgaagaag
    22081 atattcatga atccagaaaa acaagagaca gaagattata tttcaggtcg atttggataa
    22141 ggaggaaacg gaatgctacg tacacaattt gaagaagaat tgctgaatct ccataatcag
    22201 ttctacgaaa tggggatgat ggtgagcagc gccgtgcaca agtcagttcg tgcatacatc
    22261 aaacacgata aaatcttagc ccaagaagtt atcgaaaacg atataaatat caataacatg
    22321 gaaacacgct tggagaagaa aagttttgaa atgatcgcat tgcaacagcc agttacaact
    22381 gatttgcgta tgatcattac ggtcatgaaa gctagctcgg atttagaacg tatggccgat
    22441 catgcggtgt ctgttgctaa atccacgatt cgcgtaaaag ggcagacgag aataccggaa
    22501 atcgaaaaag agatctccga tatgtccgat tatgtgaaaa aaatggtgga caacgtccta
    22561 gttgcttatg tcaaaacaga cgaaaaagac gcacgtacga tcgccaatat ggatcaaaga
    22621 gtcaatgact atttcaatcg aatctataat gcaacaatca aaaatatgca ggaaaatcct
    22681 gagacagtca tcagtggaac agactacttg aatgttgcca gttatctaga acggatcgga
    22741 gactatgtga caaacatctg tgaatggatc gtctacttgg ctacagggaa aatcactgag
    22801 ttaaatacga accacaatga gattttctaa actaaagcgg tgattctgcc gtttgtttag
    22861 gaaaagaggt tgtgaaatca gcggttgtga aaaagctgtt ctgcatcaag taataagaac
    22921 agtcaaacaa aaatagctcc tcatattttt catttggctg gacttattac cgcagatgca
    22981 agcttttgaa cactgtttat tcgggaaagg gtttgtgaca aaatatgtca caaacccttt
    23041 tcatcatttc atagaaagga taaagaatgc aaaaaaaaat tagcatcatc actatatttt
    23101 ttatttgtgt gcttacttca tgggttattc agcatcaagc tgctttatat gaagtacctg
    23161 tcatcgagat cgaaaaagta cgaataaaag aggatcatca attgattaca ggaagactga
    23221 tgaacacgaa tcaaaaagga gaatcgattt atttatcggt tccttatcaa aaaaatcaaa
    23281 tagaaacagc aaatataaaa gcgagacaaa tgtatctagt ccaaatgcat ggagatgaat
    23341 ggcagctagt agcaaaaaaa aatgatggct ggcttttctt cttcacaagt atcttcattg
    23401 gcgccatgtt gcttattggc ggaaaacatg gtctatttgc tttaggaagt ctcatcatca
    23461 atatcgtttt acttttactt ttgttgctca tctttactaa aatagaaggg atttctctat
    23521 taaatatatc tatcctgttc gtcgttatag ggatgattat tagcatattg gctttagatg
    23581 gatggaatag aagcagtata atcaaaattt cagctgcagt tacgagtgtt tttttagcat
    23641 tttttatttg tcttttgaca atgaatcttt ggaaagacca aggactgcgc tatgaggaac
    23701 tgaattatct gacacgaccg tatcgttctg tttttctttc tagcgtactg attggaacag
    23761 ctggaggaac actcgatacc gttatcacag tcattgcgac attagaagaa ttgactaagc
    23821 gacaaccaga aataacagcg aaacagttat ggctttcggg aaggcaagtg ggtcgagatg
    23881 tgattggctc gatgaccaat atccttttgt tcgtctatat cagtgggtca gttccatcgc
    23941 ttcttttata tttaggaaat caatggtcgt tcaaagaaac gatagaacag catttatcat
    24001 tggaattttt acgcgtcatt gctggcagct taggaatagt attatcgatc cctatctcgg
    24061 tcctcttttt tctgactgta aggaggctga aacgatgaat gtacttatta tacttgttgg
    24121 gattttagca atcagcgtgc tacttattgg cggtacgcaa ggtatgtata ttcttttagg
    24181 cttattcatc aatttaggga tctttttctt gttgttattc ggttatcatc agaagtggcc
    24241 gatactggca ttgtcggtca taggattttt attgattgct gtggttatct tattttttat
    24301 caacggttat aatctaaaaa tgcgtgcagc ttttgtgagt atactgatct ttttattttg
    24361 tttcctacta ttgcttccta tcactgattt tttagcaatc caaggtttta caacgataga
    24421 actagaagaa ttatctggct tagataagac tttagcgatt gattttagat tacttacgag
    24481 atcgttgctt ctgattagtc ttagtggtgc tgttttagat gcgagtgtag caatttctag
    24541 tgggacattc gaagtatatc aggcaaatcc gcaattatct ttttaccaat tgcgccattc
    24601 tagtttcgct attgctaaaa aaatattggc gtcaacagta atgacacttc tttttgcatt
    24661 catgggaagt tctttagcgt tgatcctctg gtttattgat ttagacattc cttttcagca
    24721 agtgatcaat gaaaaatcat ttgttctaga atatacgatg gctattctta ccacattgtc
    24781 cgcactactt gttcttcctt taacctgcgt gactacagca tatctcttta caaaaaagaa
    24841 agaacaactc aagatggagt aaaagttaca acttaagtcc tatgacattt ttactgaatc
    24901 agtgcataat atggatgtaa ggaaaagctt gcaaacaatt ttgcttaagg aggcaatttc
    24961 catgaaagaa agagaacgta ttttagattt agtgaaaaaa ggaatccttt cgactgaaga
    25021 aggcttagat ttattagaaa gcatggcaac tgaaaaagac gaaaagcaaa tcaaaaaaga
    25081 agcagacaag gtaactgcta gtcataaaga aaaagatcag gcaagtcaat tgatcgataa
    25141 acttgaaaac ggcgaagaag aaatttctga gccagttgat ccaaaggaaa gagaaagaca
    25201 agatcaagaa aacttagaaa agatcttaga tgaactagca actgaagcga ataaaacttc
    25261 ggcgcgtcta gatgaagtaa atgctcaatt cgctgacaat aaggcagcac gcaatgagaa
    25321 acaggaagca ttgatgcagc tgaatacaaa agaagaatta ggcgagttga cagaagaaga
    25381 attagcacag cgtcagacgt tagaagcaga aatcaaagag ttagaagcta gtggcgatac
    25441 actgttagaa gaacaattga aattagaagc agaattaaaa gatatccgta agaatcaatg
    25501 gtctgagaaa aaagaaacgt ttactgataa gtttgaattg ccagatgatt ggaaagatca
    25561 agcaacagat acactgaatc aagtaggcga aaaaatgtca gaagctggat cacagttagg
    25621 aaaattcttg aagaaaacat tccaaactgt ttcagaaaca gtgaatgaca acatggaatg
    25681 gaaagatgtc agcttgcgtg tccctgggat tgcgacaacg aaatttgagc atgaatttta
    25741 ctatgaagct cctgcagcaa gtatccttga tatcaaggca gcaaacggaa acgtgacgtt
    25801 aaaaacgtgg gacagcaacg atgtgaaagt tgaagctaag atcaaacttt acggaaaaat
    25861 gggtgctgaa ccatttgaag cattctctga acggagccag attgaggtta atgaagatca
    25921 tatctccttc caaattccaa ataaacgtgt gcgtgcagac cttgttttct acttacctaa
    25981 acgagtatac gaccacgcag ctattaaact tctaaatggc aacatcatga ttgaaacatt
    26041 ggaagctaaa gatatttata caaaatctac gaatggtaac atcatcgtgg accaattaac
    26101 tgcaacgatg ctggaagtag aaggtgtaaa cggcaatatc gatattcgaa acgggaacat
    26161 cttagattct attatcgaaa cagtaaatgg tacagtgaca tttggtgcga cagcagaaaa
    26221 cctttctgtg tctttggtaa atggtgatgt acgtcttacg attaaagaag ataatttgaa
    26281 aaaagtagaa gcaagttcag tgaacggaaa tgtcaaagtc gctttaccag atggcatcgg
    26341 tttggaagga catgctaaaa caagtcttgg aagtatcaac agccgtctgt ccaattacga
    26401 agtagttcgt gagaaaaaag aacggacaaa ccaaatgttg caattccgtc gtgtttcaga
    26461 tggtgaaatc gcgcaagtgc aactttcaac gacaacagga agtatctatt taaaagatac
    26521 agataaataa agaggttgtg aaagagatgt tcagccttga gcaataagaa gcgattttgt
    26581 aaaatagctt cccctatttt acaaaattgt gccttattgc cgataggcta tctcttgaac
    26641 accgtttacc aagagattat gaacttgcca attatcgccg agtcacaagg aataatttca
    26701 aaaaaagctc gtcacgtttt atgaatatgg taatttgtga ccgagaattt tgcaaaaaga
    26761 caccgattaa gaagaaggtt gtcacaacga ttttcttcat ttaaaatagt agaacagagg
    26821 tgagacatga tgaaaaaaaa gttgacaaaa tccaataaaa atgttgtttt gacagggact
    26881 ttagcaggaa taggagaata catcgggatt gatccgactg ttatccgtgt gctttatgta
    26941 ttcctgagct tagttgcttt tggaagtcca atcattttat acattttatt agctttgatt
    27001 atcccatctg cgcgttctgc acgaacaaac tatggacata acaatgcata ttatgaaaaa
    27061 aacaattatc gtgaacaaac tcgtgaacaa acaaaaaaac gcaaagaagc ggaaaaaatc
    27121 gatgatgacg aatggagtga cttttaatgt cgtactttca acgtatttta gttaatacgt
    27181 taacattcat atcattggct gttctttttc ctgcgatggt ccatgtgagc agtatttgga
    27241 cggccgttct tgccagcttc gtattgtctg tgttgaatat gtttgtcaaa ccgattttga
    27301 cgatactgtc cctgcccttt acattagtca cattgggatt gtttacgttt gttatcaatg
    27361 cagcgattct taaaatgacc tccttttttg tgggagcaga acattttagt ttttcttcat
    27421 tcggtgcagc gttgttagta gctatcttga tgtcgcttgt caatgtaatt gtcagcgaac
    27481 ataacagtag aaaataaaag aaagctgtgc cgaactatcg gcgcagtttt tttatttaga
    27541 atcaggaatg cgttttctat tacattggta attaaataaa aacgtttttt ttaattggta
    27601 gtacttttgg ctagacaatg ataaaatgat agagaacact ctaatagaaa tgaggtagca
    27661 tgaatgtcag aagttgtaaa agttagccaa ttagtgaaaa aattatcttt ggaaatcgtg
    27721 acaggcgacg agaaaagctt agaccgtgtc atcgtaactg gggacatctc acgcccagga
    27781 ctagagttga ctggttattt taattattat tcccataatc gtttacagct atttggcagt
    27841 aaagaaatca gttttgcgga acggatgatc ccagaagagc gtttgatcat catgagaaga
    27901 ttatgtagtg aagatatgcc cgcatttatt atttcaagag gattaccagc tccagaagaa
    27961 atgatccagg cagcaaatga aaatgggata gctgtactgc gttctcccat ctcaacttct
    28021 cgcttattag gagaattatc cagttattta gatggtcgcc ttgcccctcg aacaagtgtc
    28081 cacggtgttt tagtggatgt ttacggatta ggtgtactga ttcaaggtga cagtgggata
    28141 ggaaaaagtg aaacagcgtt ggagttgatc aaacgcggtc atcgattgat cgcagacgat
    28201 cgagtagatg tttatcagca agatgaatta acggtgatcg gagaaccgcc taaaatcctg
    28261 gaacatctga ttgaaatccg aggaatcggg atcattgatg taatgaatct ttttggtgcg
    28321 agtgcggtac gtggctctat gcaagtccag ttggctgttt atctggaagc atgggcaaaa
    28381 gataagaaat acgaccgtct gggctctgaa gacacgaccg ttgaaatcgc ggaagtaggc
    28441 attccacaaa taaaaatccc tgtcaaaaca ggacgaaacg ttgcaatcat cattgaagta
    28501 gccgcgatga atttccgtgc acgtacaatg ggctttgacg caacgaaaac atttgaagaa
    28561 agattaagtc gcttgattga agaaaactca ggcaacgact agcaaggagt gacaatatgt
    28621 tagcacaaat caatcgagtt gcttttgagc ttgtagggat tcctatctac tggtatgcat
    28681 tgatcatcgt atcaggtatc attatcgcca tgtggcttag cagcagagag gctgttcggg
    28741 taggattaaa agcagatgat gtgacagatt ttatgttgtg gggattgcct atctccatta
    28801 ttggcgctcg cttatattat gttttatttg atcttcccca gtatatagct gatccaatcc
    28861 aaatattcaa tatccgttca ggaggcttag ctatttatgg cggactgatt gcaggcgcga
    28921 tcacgctgta tttttttact aaatatcatt ttatttcttt gtggactttt ttagatatcg
    28981 ctgcaccaag tgtattatta gcacaagcaa tcggtcgttg gggaaatttc atgaaccacg
    29041 aagcatatgg accagacacg acgcgaagct tcttagaaag tctgcattta ccgcaattca
    29101 tcattgataa tatgtatatc gaagggatct atcgtcaacc aacatttctt tatgaatcac
    29161 tttggagttt gattggattt attttgcttt tgtttttacg aaagaaacca caccttttga
    29221 aaaaaggtga agtcctttta tgttatctaa tgtggtatag tttcgggcgt ttctttattg
    29281 aaggattacg tacagacagt ctttactttt taggtgtgat ccgtatttct caattattat
    29341 ctgctgtgtt atttgtcggt acattgattc tatttatttg gcgcagaaaa aaaggaaatt
    29401 taccggatta tgaccgctca ttaggaaaaa atcaacaaat tatctgattt ttagagcgtt
    29461 aaaaatgaaa aaaatttcag gagtggtaaa atgaattata gagtagcggt tttaggacca
    29521 ggctcttggg gtactgcttt ggcacaagtc ctcgccgaaa acggacatga cgttcggatt
    29581 tggggacatc gtgcttcaca agtagaagaa atcaacaccc aacacacgaa tcaacgttat
    29641 ttaccagatc attgtctacc cgattccatc caagcattca ccaatatgga agatgcagta
    29701 aaagacgcag atgcggtgct attcgtcatt ccaacgaaag caatacgttc tgttgcaaaa
    29761 gaactagtgc ctaaattgaa tacaaagcca gtgatcatcc atgcaagtaa aggattagaa
    29821 caggggacac ataaaaggat ctctgacatc ttgttagagg aaatcccagt agaaaaaaga
    29881 aaagctgttg ttgttctttc tggaccaagc catgcagaag aagtagcgaa acatgacatc
    29941 actacgatca cagctgcaag tacagatgca aaagcagcaa aatatgtaca agagctgttc
    30001 atgaataatt attttcggat ctataccaat cctgatgtga tcggtgtaga gatgggggca
    30061 gctttgaaaa atattattgc tattggtgct ggcgctattc acggcttagg gtttggcgat
    30121 aatgcaaagg cagcaatcat gacgcgcgga ttagctgaga tcagccgttt aggtgtagca
    30181 atgggtgcca acccgctgac ctttatcgga ttaagcggag taggcgatct agtcgttact
    30241 tgcacaagtg ttcattctag gaactggcgc gcaggcaact tgttaggaca agggcagccc
    30301 ctagaagagg tgctagccaa tatgggaatg gtcgttgaag gtgtgaatac tacccaagca
    30361 gcgatggaac tagcccaaat aatggaaatc gaaatgccca tcactcaaac aatctatgaa
    30421 gtgctgtatg aacaaaaaga aatcaaaaca gccgcaaaag aaatcatgtt acgtgatggg
    30481 aaaaaagaaa atgaattctc attaacaatt ttttgaagga gcgaatgtat atgaaagtca
    30541 aaaaagcagt tattccagca gcaggattag gaacaagatt tttaccagca acaaaagcta
    30601 tggcaaagga aatgttgcca attgttgata aaccaacaat ccagttcatc gttgaagaag
    30661 cgttgaaatc aggtatcgaa gacatcttga tcgttacagg aaaagctaaa cgaccaatcg
    30721 aagatcactt tgattcaaat attgaattag aaacaaacct aagtgaaaaa ggaaagaccg
    30781 aattattgaa attagtagaa gaaacgacag atgtcaactt gcatttcatc cgtcaatctc
    30841 atccaaaggg tttaggacat gccgttcttc aagcaagagc ctttattgga aatgaaccat
    30901 ttgtcgttat gctaggcgat gatataatgg aagacgaagt accattgaca cagcaattaa
    30961 tcgatgatta cgaacgtact catgcttcta cgatcgccgt tatgcaagtt cctcatgatg
    31021 aaacttcaaa atacggaatt atcaatccag gagaagtatt ggaagatggg ttatacaatg
    31081 tcaaaaactt tgttgaaaaa ccagatccaa gcaaagcacc aagtgattta gctattattg
    31141 gacgttactt attgactcca gaaatttttg atgtattgtc cgagcaacaa ccaggagccg
    31201 gaaatgaaat ccaactaact gacgcaatcg atacattgaa taaaacacaa cgcgtatttg
    31261 cccgtaaatt cacaggtaaa cgttacgatg tcggtgacaa atttggtttt atgaaaacaa
    31321 gtattgaata tggtctaaca catccagaag taggtgcacc tttacgtgag tacatcctgt
    31381 ctttaggtaa aacattagaa gcagaaggaa gcaagatcga tcataatcca aaaggaataa
    31441 cagaaatcaa agaagaaaag aaaaaataac ccttttttct aacgagcttc agctgctaat
    31501 tgaataaaaa gtagttgaag ctcgttttta tttgtttaaa aaacacgaaa atgctatcct
    31561 tatagaaaag agagacaaga agggagtttg atcatgtcag gaggagaaat tgcaggattg
    31621 atcgcagcaa tcgcctttgc gatacttgtc gtttttatcg ttcgtgtgtt gttgcaagtt
    31681 tctaaaactt tagaaaaagt agatcagact gtagcagaag caaatacgac gatcgaaatc
    31741 gtcacaaaag acgtagatct tttgtctaga caagtagaag gcttactggt caaaagtaat
    31801 gaactgctct tggatatcaa tggaaaagtc gcaacgatcg atccattgtt cacagcagtt
    31861 gctgatttaa gtgaaagtgt atcagaactt aatcattcta gtaaaaacat cgcgacgaaa
    31921 gtcggcggaa tcggtaaaac gacagctaaa gcgacggttg ccggaaaagt cggtgggaca
    31981 gcgatgaaat tttttaaaaa caaaaaacat actgaaacga caggaggaaa ataaaaatgg
    32041 ctaaaaaagg tggattttta ttaggtgcag tagtcggagg cacagccgca gcaatcgccg
    32101 cgttattgtt agcaccaaaa tctggtaaag aacttcggga tgaattagct gcccaagcgg
    32161 atgatttgat ggatatggct tcagattaca cagatatggc gaaagaaaaa tcgactgagt
    32221 taacaggtat tgcaaaagaa aaagcgcaag atctttctca acaagcaggt gatctagcag
    32281 gtagtgtcaa acaaaaagta agtgaatcag cagatgaagc aggaagtgaa tctgacgata
    32341 tcttgttaaa tcttaaagaa caatcagctg acttatctaa tcgtttcaaa aaaacggcag
    32401 aagatatgaa aaaacctgca gatgaattag gaagtattgc taaagatact tcagaagata
    32461 tcataattga tgtaaaagac gctgctggta aagcaggaga tactgtcaat gaaggaatgt
    32521 cagaagcaaa accagttgca gatgactcaa aagaaatgat gaaaatggca aaagaagatg
    32581 cgaaagaagc taaaaaagaa ataaaagata caatgacaga ttcatctaca aatcactaaa
    32641 atcacaaatt tatagaat
//
LOCUS       DAFBVQ010000026        31318 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.026, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000026 DAFBVQ010000000
VERSION     DAFBVQ010000026.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 31318)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 31318)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..31318
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.026"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            285..1208
                     /gene="truB"
                     /locus_tag="LLC22_001418"
     CDS             285..1208
                     /gene="truB"
                     /locus_tag="LLC22_001418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(55) synthase TruB"
                     /protein_id="HBK5434701.1"
                     /translation="MDGLLPLWKERGMTSHDCVFKLRKILHTKKIGHGGTLDPDVDGV
                     LPICIGKATKVIEYLTDSGKIYVGEITLGFSTTTEDRSGERVETKPVDMSLSEKKIDE
                     VMASFIGEITQIPPMYSAVKVNGKRLYEYARNNETVERPVRKAQIYRFIRTSELTRDE
                     VTGTISWRFEVECGKGTYVRTLAVDTGKKLGYPAHMSDLTRTASAGMSQKDALTLEEV
                     AQAVKNGTIDDCLLPIEKGVERFKRVDITDEVWQKVKNGMRLDYTVFALPEMPSEEIA
                     LFYKGKVVSIYQPNPKEKNKLKPSKVLRNEE"
     gene            1212..2150
                     /gene="ribF"
                     /locus_tag="LLC22_001419"
     CDS             1212..2150
                     /gene="ribF"
                     /locus_tag="LLC22_001419"
                     /EC_number="2.7.1.26"
                     /EC_number="2.7.7.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342162.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="riboflavin biosynthesis protein RibF"
                     /protein_id="HBK5434702.1"
                     /translation="MNIIKIRHPYQSEQIPEDDVVLVLGFFDGVHIGHQKVIKTGMEI
                     AQKEGLKLALMTFNQHPSIVFKKIDPSSVKYLTSLKQKEEKMAALGIDYLYEVDFTSS
                     FAHLAPQEFVDQYIVGLHAKYAVSGFDYTYGPKDIADVAHFPEYAKGRFKIVTVSKEE
                     QGEKISSTRIRGLLDSGQVKEAAKLLGCTYEVEGVVVHGDARGRLLGFPTANVKVKST
                     VHLPKEGVYVSEIKIGETWYPAMGSIGHNDTFGEGRELTVELYILDFNQDIYGEHVAV
                     RWNQFLRDQVKFSSVEELIEQLKEDEQATAEYFSQQ"
     gene            2502..3287
                     /locus_tag="LLC22_001420"
     CDS             2502..3287
                     /locus_tag="LLC22_001420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5434703.1"
                     /translation="MYKELENKVAVVTGGSKGIGTAIAQRFGKEKMNVVVNYNSDKEG
                     AEKAVKAIEEAGGKAVSVQADVSSEEGIQRLLDTALENFGTLDVWVNNAGMENQHPTH
                     ELSLEDWERVLKVNLTGVFIGTKAALNYFTENNKKGNIINMSSVHEQIPWPTFAHYAA
                     SKGGVKLFTETVAMEYAPKGIRINSIGPGAIRTPINAAKFDDPEQKELLESMIPLGRV
                     GEPKEIAATAAWLASDESSYVTGITLFADGGMTLYPSFQGGKG"
     gene            3300..4151
                     /locus_tag="LLC22_001421"
     CDS             3300..4151
                     /locus_tag="LLC22_001421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transporter"
                     /protein_id="HBK5434704.1"
                     /translation="MGLLIALIPAVGWGIQPLILKKIGGRPTNEILGTGIGAVLVGLL
                     VQLFASPAGISVTTFLISLLSGAFWVIGQTGQYTSFNLIGVSKTMPISTALQLVGTSL
                     IGVFAFGEWSGSMGKIIGAAAIILLVFGSALTAISDDPGKKGGITKGISLLASTSIGY
                     WVYSALPKLVDASGLSIFFPQMIGVFLGAVIYVIFRKPTAFSEDKSWKATIVGAIFSV
                     SALAYIFSANENGVATAYIITQLNVVISTLGGMYILHENKTPKEKKLTIIGLLLIVVG
                     SMVTVFI"
     gene            complement(4275..4727)
                     /locus_tag="LLC22_001422"
     CDS             complement(4275..4727)
                     /locus_tag="LLC22_001422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434705.1"
                     /translation="MKDFYSVNELAEQLGVTTRSIRNYLHEGKLKGTKVGGQWKFSER
                     NLFEFLYGDQAEEAAKEMQRFMLNAPITMRFNLQYRDFTAINQFREQLVQYHNDVYAN
                     KKDRLLQYDLYKDNHAEILIGGNFNYVVNFSQWINEKLLIQTDISLVS"
     gene            complement(5192..5560)
                     /locus_tag="LLC22_001423"
     CDS             complement(5192..5560)
                     /locus_tag="LLC22_001423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1801 domain-containing protein"
                     /protein_id="HBK5434706.1"
                     /translation="MEKFQPIINQIKEKEHQQKIKDLFAKITETYPQLDTTVKWNQPM
                     FTDHGTFIIAFSFAKNHFSIAPEKAAIRALEKNIQEAGYVYTDNVIKVPWKSVINWEL
                     IEQLISFNIEDKKGHDKFWR"
     gene            5710..6192
                     /locus_tag="LLC22_001424"
     CDS             5710..6192
                     /locus_tag="LLC22_001424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="prolyl-tRNA editing protein"
                     /protein_id="HBK5434707.1"
                     /translation="MIDLAKKFLHENIYFELYHHRAIYTNEDALVIKKEQGFTGTETK
                     SLFLKDKKDNNYVYLTFTTKQTDFKALGKIVGKRLSIVSSERMEEQTGQKQGAVSPFG
                     YEKQIPIIIDEELLSNEKLVFAPGRPDQTMVIQTVDLNKIIQLLEMPIFLMPANEKNN
                     "
     gene            6229..7239
                     /locus_tag="LLC22_001425"
     CDS             6229..7239
                     /locus_tag="LLC22_001425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LD-carboxypeptidase"
                     /protein_id="HBK5434708.1"
                     /translation="MISYPLLERNATIGVTAPSSGVSEEHHSLLESALKRMEEKSFQV
                     VTGKTLWTQDKEKSGPARKRADEFNQMMQDENIQMIFPTWGGELLIEILDFVDFDALQ
                     PKWIVGYSDISTLLLAVTLKTGIATAHGTNLIDLRGEYLDETTAMWESVLKTREGESI
                     LQQSSEKYQKVWPHEHSSSSVFHLTEPTNWQSVSGDAVRMKGRLLGGCIDTIRHLIGT
                     PYGDVQSFKRKYNDGKPILWFLENCELSSVDLRRSLVQMKLAGWFDGSSGIMFGRSAA
                     EDLLDYKMKDVYEDLSKELKLPILYDIDCGHVPPQLTLINGAYAEVAVEDRKATVLQT
                     FI"
     gene            complement(7354..8067)
                     /locus_tag="LLC22_001426"
     CDS             complement(7354..8067)
                     /locus_tag="LLC22_001426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289536.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434709.1"
                     /translation="MKKLGFILLLVSLFLVGCTSPSKENSDPSATTDKSSIRQTSSAE
                     KSSTQKSASTETNTSSTSSKVSEPNTSSTSSSTVETNISSSTIDTTSSQSSQSIDPLA
                     GYSDLQIEYARVWLAIRGNTFRDTSGDFELHVIHYPAGTPIAPYDAGSAVYPKDVVML
                     TGKYSYQGVLVYSSNHDGTITSYPVPSHWQMPADQTSYPAFIRETTQEIIDNASVVAI
                     PTGNPNDVKQLIDVTVIDN"
     gene            complement(8257..8847)
                     /locus_tag="LLC22_001427"
     CDS             complement(8257..8847)
                     /locus_tag="LLC22_001427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400305.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine amidotransferase"
                     /protein_id="HBK5434710.1"
                     /translation="MKTAITFLLEEYADWEGAYITSTLNQNEKWQNKTASIQSEVTSI
                     GGLKTKIDYLIEQIPEKVDLFIMIGGNSWDIKNHHLYQIIDKLLKTDVPVAAICGAVD
                     YLAQSGLLQGYKHTGNAQFPWLESENYQNKEDFIEQQAVKDRNLITANGTAPIEFTDL
                     ILQAVHFETEEIREKTIRLYKLGFYDYYKKYGDPFS"
     gene            9331..9558
                     /locus_tag="LLC22_001428"
     CDS             9331..9558
                     /locus_tag="LLC22_001428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenosine deaminase"
                     /protein_id="HBK5434711.1"
                     /translation="MKIAFHIFADFDLMPKVSFAITVYREAVKAPCSSDDNKQAFLEL
                     GFLDSKYAAYFNELVLERDFKKVENRHDFST"
     gene            9574..10740
                     /locus_tag="LLC22_001429"
     CDS             9574..10740
                     /locus_tag="LLC22_001429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oxygen-independent coproporphyrinogen III
                     oxidase"
                     /protein_id="HBK5434712.1"
                     /translation="MIETINPAENKVSAYIHIPFCEHICYYCDFNKVFLEGQPVDEYV
                     EMLLNEMKIMLESHPTANLETLYVGGGTPTSLSAKQLDRLLSGAREILPFQNGNEFTV
                     EANPGDLTREKLQVMKNYGVNRLSMGVQTFDNRLLKKIGRKHTAEDVYQTMQFLEAEN
                     FTNVSIDLIYALPGQTLEGYLDTLEKALALDLPHYSLYSLILENKTMFMNWVRQGRLE
                     LPDQETETRMFEETIEAMEKHGRHQYEISNFGLSGHESQHNLMYWNNDHYFGFGAGAS
                     GYLGDIRYRNKGPIQHYLRPLRANERPVLEEEKLTRKNQIEEEMFLGLRKKTGITKKH
                     FYDRYQKTIESVYGDVLRELEQEGLLVNEEDRVYLTPRGTFLGNNVFERFLFEK"
     gene            10974..12017
                     /gene="hrcA"
                     /locus_tag="LLC22_001430"
     CDS             10974..12017
                     /gene="hrcA"
                     /locus_tag="LLC22_001430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340771.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="heat-inducible transcriptional repressor HrcA"
                     /protein_id="HBK5434713.1"
                     /translation="MLTKRQNDILRLIIQHYTSSGVPVGSKTLMSEGVKASSATIRND
                     MKALEDEGLLLKTHSSSGRIPSALGYRYYVDHLLKPARVAEDDLLLIRQSLGREFHEI
                     NEIIKQSAEILSELTSYTTFSLGPEIKDRRLTGFRIVPLNNRQIIAIVVTDMGNVESQ
                     VFTLPEYMGSQELEKMVQIVNDRLVGDPLMTVYHKLRTEIPMILHKYFQTTEGMSQLF
                     DTVLGHVFEDKVYVSGQMNLLDYEPRQDLDQFKSMFSFMKDSDGLTQMITPMDSNIHI
                     KIGAELGNDLLQNMSMIQASYEIDGHGRGTIALLGPTSMPYSRMFGLVDVYRRELAAK
                     LADYYRSLDLSNS"
     gene            12111..12674
                     /gene="grpE"
                     /locus_tag="LLC22_001431"
     CDS             12111..12674
                     /gene="grpE"
                     /locus_tag="LLC22_001431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide exchange factor GrpE"
                     /protein_id="HBK5434714.1"
                     /translation="MKENQEELDKEMTDAQPEPEIDVEAAEDSGISEAEAEEFETAKL
                     KAELEEMEDKYLRARAEIANMANRGKNEREQLQKYRSQDLAKKLLPSIDNLERALATE
                     VSDDQGAGLKKGVEMVLESLRNALEEEGIEKIPAKGEAFDPNLHQAVQTVPATEDTPA
                     DTIVEVLQEGYKLHDRVLRPTMVIVAQ"
     gene            12725..14554
                     /gene="dnaK"
                     /locus_tag="LLC22_001432"
     CDS             12725..14554
                     /gene="dnaK"
                     /locus_tag="LLC22_001432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016635026.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaK"
                     /protein_id="HBK5434715.1"
                     /translation="MSKIIGIDLGTTNSAVAVLEGNEAKIIANPEGNRTTPSVVSFKN
                     GEIQVGEVAKRQAVTNPNTISSIKRHIGEAGYKVDVEGKSYTPQEISAMILQYIKGFA
                     EDYLGEKVEKAVITVPAYFNDAQRQATKDAGKIAGLEVERIVNEPTAAALAYGLDKTD
                     RDEKILVFDLGGGTFDVSILELGDGVFDVLSTAGDNHLGGDDFDNKIIDYMVAEFKKE
                     NSIDLSQDKMALQRLKDAAEKAKKDLSGVSSTQISLPFITAGESGPLHLEMTLTRAKF
                     DELTADLVERTKVPVRQALKDAGLSQSEIDEVILVGGSTRIPAVVEAVRKETGKEPNK
                     SVNPDEVVAMGAAIQGGVITGDVKDVVLLDVTPLSLGIETMGGVFTKLIDRNTTIPTS
                     KSQVFSTAADNQPAVDIHVLQGERPMAADNKTLGRFQLTDIPAAPRGIPQIEVTFDID
                     KNGIVNVSAKDLGTQKEQKITIKSSSGLTDEEIERMVKDAEANAEADKARKEEVDLRN
                     DVDALLFSVDKTLKELEGKVDEEEVKKAETARDELKAAVEANNIEEMKTKRDALNEIV
                     QNLTVKLYEQAAQQQAQENPEAAQGGADDVVDADFEEVDGDDK"
     gene            14705..15871
                     /gene="dnaJ"
                     /locus_tag="LLC22_001433"
     CDS             14705..15871
                     /gene="dnaJ"
                     /locus_tag="LLC22_001433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="molecular chaperone DnaJ"
                     /protein_id="HBK5434716.1"
                     /translation="MATKRDYYEVLGLSKGASEDEIKKAYRKLSKKYHPDINKEPDAE
                     EKFKEVSEAYEILSDPQKRAAYDQYGHAGTDPNYGAGGAGGGFGGFGGFSGGGFGGFE
                     DIFDSFFGGGGRSVDPNAPRQGADLQYTVDLSFEEAIFGVEKEIKYNREEICHTCGGN
                     GAKPGTQPTTCHKCHGAGTINVERQTPLGRVMSRQTCDVCHGTGKEIKEPCPTCHGSG
                     HEKKAHSVKVNVPAGVEEGQQMRLAGQGEAGENGGPFGDLYVVFRVEESDIFDREGSE
                     IYYELPLSFVQAALGDEVQVPTVHGDVKLKIPAGTQTGTNFRLRGKGAPKLRGGATGD
                     QHVKVKLITPKNLNEQQREALRAFAEAGGIKVEEQQEDGFFDKFKDAFGGKKRK"
     gene            complement(15953..16618)
                     /locus_tag="LLC22_001434"
     CDS             complement(15953..16618)
                     /locus_tag="LLC22_001434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434717.1"
                     /translation="MELDFSSPYYVVVGQLSDNQQLCQERINPLLELLERVFSYYGQA
                     LLTVHRQQIIILVNRISRASLLSLLDKIQTKFNKMYQLQLNFGIGSLCYTEQETPQSF
                     LHAKQVCEWIAFHQSVNEIRFFEDLDLGIVLPAIPSDQRTLYVKRILKSLTEEEVHLF
                     KKTLACFSKNNGSIKNCSEELFIHKNTLQYRLNKFHSLTGYTPRNYDDYHILKLAFLL
                     VQT"
     gene            16594..16767
                     /locus_tag="LLC22_001435"
     CDS             16594..16767
                     /locus_tag="LLC22_001435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296523.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434718.1"
                     /translation="MEKKNQAQLSEGGIDYVLDIINEPMVLSYAMEQVERLLVCAGKQ
                     AMRLIRLGEKIRR"
     gene            complement(16812..17549)
                     /locus_tag="LLC22_001436"
     CDS             complement(16812..17549)
                     /locus_tag="LLC22_001436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010760672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5434719.1"
                     /translation="MAEKILVEHLVKKYGDNTVLNDINVSINEGDVVCIIGPSGSGKS
                     TFLRCLNRLEEPSDGEIIIDGAHLMDKSTDINLVRQHIGMVFQHFNLFPHLSILENII
                     LAPMDLKKESREEAEKKAIKLLQTVGLEDKKDMYPEMLSGGQKQRVAIARALAMNPDI
                     MLFDEPTSALDPEMVGDVLNVMKKLAEQGMTMVIVTHEMGFAKEVANRVMFIDDGNFL
                     EDGTPQQIFENPQNERTKDFLNKVLNI"
     gene            complement(17551..19053)
                     /locus_tag="LLC22_001437"
     CDS             complement(17551..19053)
                     /locus_tag="LLC22_001437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294446.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter substrate-binding
                     protein/permease"
                     /protein_id="HBK5434720.1"
                     /translation="MKRKHLFHSFVFLMTGLVTLAFGHVAQADNTTTAESSTSETMQK
                     IEPKKDVYVIASDSAFAPFEFQNAKGEYEGIDVKLMENIAKLQGFNIRMDYRGFSAAL
                     QALESGQADGMIAGMTVTDERKKSYDFSDSYFDSGIQLAVKKGDTSIKSYEDLKGKTV
                     GAKVGTESAEFLSDHESEYGYSIKYFDAADQLYDGLKVGAIDAMMDDYPVIGYAIKQG
                     QELETPIKKESGGKYAFAVKKGQNPELLNMFNEGLKELKRTGEYDKIIKEYVADGSET
                     SSESSTADESTFLGLIQNNYQALLKGLWRTILLTLISFALAIVIGVIFGLFSVAPIRA
                     LRTIASIYVDIIRGIPMMVLAFFIFFGLPGIVGFTIPDFLAGVITLTLNASAYIAEIV
                     RGGINAVPVGQMEASRSLGLSYNRTMQKIILPQAIRIMIPSFVNQFVISLKDTTIISA
                     IGVVELLQTGKIIVARTTQSTYVYLIIAIMYLILITALTKLAKVLEKKVK"
     gene            19312..21306
                     /gene="uvrB"
                     /locus_tag="LLC22_001438"
     CDS             19312..21306
                     /gene="uvrB"
                     /locus_tag="LLC22_001438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrB"
                     /protein_id="HBK5434721.1"
                     /translation="MIERDTSRHFELVSKYQPAGDQPEAINQLVDGVVGGKKAQILLG
                     ATGTGKTYTISNLIEKVNKPTLIIAHNKTLAGQLYGEFKEFFPNNAVEYFVSYYDYYQ
                     PEAYVPSSDTYIEKDSSVNDEIDKLRHSATSSLLERNDVIVIASVSCIFGLGSPFEYQ
                     KQVVSIRQGAELDRNQLIRDLVSIQFERNDIDFQRGRFRVRGDVVEIFPASRDERALR
                     VEFFGDEVERIREVNALTGEVLGETEHVAIFPATHFVTNDEHMEHAVANIKEELEQRL
                     TVLRNENKLLEAQRLEQRTNYDIEMMLEMGYTSGIENYSRHMDGRKEGEPPYTLLDFF
                     PEDFLIVADESHVTMPQIRGMYNGDRARKQMLVDYGFRLPSALDNRPLRLEEFEKHVN
                     QIIYVSATPGPYEHEQTDTVIQQIIRPTGLLDPVIEVRPIMGQIDDLVGEINERVEKD
                     QRVFVTTLTKKMAEDLTDYFKELGIKVKYLHSDIKTLERTEIIRDLRLGEFDVLVGIN
                     LLREGLDVPEVSLVAILDADKEGFLRSERSLVQTIGRAARNEEGKVIMYADKVTDSMR
                     LAMDETSRRRTIQQKYNEEHGIVPKTIIKEIRDLISITKESEDDTKEAVQVSYEEMTK
                     EEKDTLLMKLEKEMKDAAKALDFETAANVRDMILELKASK"
     gene            21316..24132
                     /gene="uvrA"
                     /locus_tag="LLC22_001439"
     CDS             21316..24132
                     /gene="uvrA"
                     /locus_tag="LLC22_001439"
                     /EC_number="3.1.25.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629327.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="excinuclease ABC subunit UvrA"
                     /protein_id="HBK5434722.1"
                     /translation="MANDKITIHGARAHNLKNIDVTIPRDKFVVVTGLSGSGKSSLAF
                     DTLYAEGQRRYVESLSAYARQFLGQMDKPDVDSIDGLSPAISIDQKTTSKNPRSTVGT
                     VTEINDYLRLLFARVGHPICPNDHIEITSQSVDQMADQVMALPERTKIQVLAPIVVKK
                     KGQHKKIFERIQKEGYVRVRVDGEIYDLSEVPELEKNKKHDIAIVIDRIIVKEGIRSR
                     LFDSLEAALRLADGYALVDVIGEEEMLFSEHYACPYCGFTVGELEPRLFSFNAPFGAC
                     PDCDGLGVKLEVDQDLVIPDRTKTLSQGAIVPWNPISSQYYPQMLAQACESFGIDLDT
                     PFEELPEEHQEIILNGTDDLFHFHYENDFGGVRDVETTFEGVLKNIERRYHDTNSDFT
                     REQMRLYMTELTCQTCKGYRLNPQALSVQINGTNIGQTNELSIQKAVDFFSNLTLSEQ
                     EKVIAKPILKEVNDRLSFLENVGLDYLTLSRASGTLSGGEAQRIRLATQIGSNLSGVL
                     YILDEPSIGLHQRDNDRLIGSLKKMRDLGNTLVVVEHDEDTMWAADYLIDVGPGAGEQ
                     GGQIVAAGTPEEVANDENSLTGKYLSGKKSIPVPKERRKGNGKAIKITGASENNLKNI
                     SVEFPLGEFVAVTGVSGSGKSTLVNSILKKSLAQKLNKNSAKPGKFKTISGYESIEKI
                     IDIDQSPIGRTPRSNPATYTSVFDDIRGLFAQTNEAKMRGYKKGRFSFNVKGGRCEAC
                     RGDGIIKIEMHFLPDVYVPCEVCHGKRYNSETLEVHYKGKSIADILEMTVEDAVEFFK
                     HIPKIHRKLQTIVDVGLGYVTMGQPATTLSGGEAQRMKLASELHKISNGKNFYILDEP
                     TTGLHSDDIARLLHVLQRLVDAGNTVLVIEHNLDVIKTADYIIDLGPEGGEGGGTILA
                     TGTPEEIINVKESYTGHYLKKIMV"
     gene            24395..25660
                     /locus_tag="LLC22_001440"
     CDS             24395..25660
                     /locus_tag="LLC22_001440"
                     /EC_number="6.3.1.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-aspartate ligase"
                     /protein_id="HBK5434723.1"
                     /translation="MMNSIENEEFIPILLGSDMNVYGMARSFNEAYGKICQAYASDQL
                     APTRYSKIVNVEVIPGFDKDPVFIETMLRLAKERYSDKSKKYLLIACGDGYAELISQH
                     KQELSEYFICPYIDYSLFERLINKVSFYEVCEEYDLPYPKTLIVREEMLVNGHLEQEL
                     PFEFPVALKPANSVEYLSVQFEGRKKAFILETREEFDLILGRIYEAGYKSEMIVQDFI
                     PGDDSNMRVLNAYVDEDHQVRMMCLGHPLLEDPTPASIGNYVVIMPDYNEKIYQTIKA
                     FLEKIEYTGFANFDMKYDPRDGEYKLFEINLRQGRSSFFVTLNGLNLARFVTEDRVFN
                     KPFVETTYGTNQSDKARLWMGVPKKIFLEYARENEDKKLAEQMIKENRYGTTVFYEKD
                     RSIKRWLLMKYMFHNYIPRFKKYFHVKEG"
     gene            25664..26395
                     /locus_tag="LLC22_001441"
     CDS             25664..26395
                     /locus_tag="LLC22_001441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate racemase"
                     /protein_id="HBK5434724.1"
                     /translation="MENFFSILGGMGTMATESFVRLINHRTKATKDQEYLNYVLFNHA
                     TVPDRTAYILDRSEENPMPFLLDDIEKQNLLRPNFIVLTCNTAHYFFEELQAATDIPI
                     LHMPREAANELVRQHTTGRVAILGTEGSMKAGIYEREVKNLGFETVIPDTALQEKINY
                     LIYHEIKESDYLNQELYYEILEEAVERLNCEKVILGCTELSLMHEFAEDNHYPVIDAQ
                     SILADRTIERALAERSEALDTASEK"
     gene            26530..27414
                     /gene="rapZ"
                     /locus_tag="LLC22_001442"
     CDS             26530..27414
                     /gene="rapZ"
                     /locus_tag="LLC22_001442"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317628.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNase adapter RapZ"
                     /protein_id="HBK5434725.1"
                     /translation="MTDNLQLVIITGMSGAGKTVAIQSFEDMGYFCIDNMPPRLIPKF
                     WELIKESGKVTKMALGVDLRSRSFFEEIQNMLIEIENTNFIDTSILFLDASDEELVAR
                     YKETRRAHPMAMDGLITEGIRKERAILDDLKAQASVIIDTTTLTPRQLREKINESFKS
                     KGDQGFRIEFVSFGFKYGLPIDSDIVMDVRFLPNPHYIPELRPLTGKDQPVYDYVMSF
                     DETQSFYHKFLDLLETVLPGYIKEGKSSLTVAIGCTGGQHRSVALTERLANALGKNYK
                     VNVTHRDKDKRKETVNRS"
     gene            27411..28409
                     /locus_tag="LLC22_001443"
     CDS             27411..28409
                     /locus_tag="LLC22_001443"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289697.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YvcK family protein"
                     /protein_id="HBK5434726.1"
                     /translation="MKMKTYRIRKPKIVVVGGGTGLPVILKSLRNQGADITAVVTVAD
                     DGGSSGAIRESIAMAPPGDLRNVLVALSDMPQFYEDIFQYRFKKEDQFLANHTIGNLI
                     IAAVSEMRGSTYEAIQLLAKMMHVDGHVYPSSETPLTLHAVFKDGTTAVGESKIAINR
                     KTIDRVYVCNTNDKSEAKAARKVVSAIMDADMVVLGPGSLFTSILPNLVIPEIGEAML
                     KTTAETVYICNIMTQKGETEHFTDADHIRVLHKHLNQPFIDTVLVNTEKVPEDYMDPE
                     IYDEYLVQVAHDFNGLRNEGCRVISTDFLELKDGGVFHDGDKVVEELFRLVFGSKY"
     gene            28443..29378
                     /gene="whiA"
                     /locus_tag="LLC22_001444"
     CDS             28443..29378
                     /gene="whiA"
                     /locus_tag="LLC22_001444"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752056.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding protein WhiA"
                     /protein_id="HBK5434727.1"
                     /translation="MSFAADVKKELTGLEVHREHAKAELAALLRMNGSLGIVNQQFIL
                     NVQTENAAIARRIYSLLKDHYQVRSELLVRKKMKLKKNNVYIVRLKQGTKDVLMDLDI
                     MDGMMFNGHVSDEIMGNSQKMRSYLRGAFMASGSVNNPETSRYHLEIFSIYEQHNQDI
                     CDMLNYYGLHARTLERRNGYISYLKGAEKIADFLTLIGATNSMLRFEDVRIVRDMRNS
                     VNRLVNCETANLNKTIDAASKQIENIELIEAKVGLHALPEKLQEIAELRLQHPEVSLK
                     ELGEMIPSGAISKSGINHRIRKINEFAEKLREEAV"
     gene            29921..30571
                     /locus_tag="LLC22_001445"
     CDS             29921..30571
                     /locus_tag="LLC22_001445"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434728.1"
                     /translation="MFIKGGQKMCFFTTFTIIMIAVLFIFLDIAKRNTAFLLYRVLLR
                     AGLITFISIVGFFLFTVIVFIWRTTAPPLPEITYGEFPFSLEYEIDEERILIEDTVIA
                     EFIGSFRGNVTTQPRRSWSIKLLNNSGELKAFHYEFLIIESEDVTITLSSGSAGYFMN
                     DGGSKPQLTVRDRIAGFMHFSHYDLEEARKILAEYGITLINWEYAPPIRNFFNDYY"
     gene            30758..>31318
                     /locus_tag="LLC22_001446"
     CDS             30758..>31318
                     /locus_tag="LLC22_001446"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF443 family protein"
                     /protein_id="HBK5434729.1"
                     /translation="METVRLWIFMKNFRSALRYVILESKSGYYLIDTDHYTFWGGYLF
                     PIFNWIIPHKVMKINLPAEEINRLILNKDLQRKREKEHSNVAWIGPAFAVVTSSIVGP
                     MLESIYSDFSIGIRYLFVTLSIAVLLCIKGYVSKKNKDILTLIGVNNLSSTKIILFPE
                     SIKEGSRLLIIFIMLILFSVLFGVMFI"
BASE COUNT        10348 a         5258 c         6658 g         9054 t
ORIGIN      
        1 ctggaagaat ggccagtctt ttttttcgtt tttgggaagt gaaaaccaaa ctatttacct
       61 gtaagccacc cataaatcca atcaaatggt gcaaagaaaa aatcttccat tctattccct
      121 cctttaaaaa agcataacat gatttctatt tacgtgagca tgaattttgt tacgttttta
      181 ttgccgaaaa ataaaaaccg ttcattatga tgtcaaattc gtcagtaatt gatgcaatgt
      241 gttataataa ttcagttaaa tcaaaaatga aatggagaaa agacatggac gggttattac
      301 ctttatggaa agaacgcgga atgacaagtc atgattgcgt attcaaatta agaaaaatct
      361 tacatacgaa aaaaatcgga catgggggta cgcttgaccc agacgtagac ggtgtgttgc
      421 ccatttgtat tggaaaagcc acaaaagtta tcgaatattt gacagattct gggaaaatct
      481 atgtaggcga gataactcta ggtttcagta caacgacgga agatcgatcc ggagaacggg
      541 tagaaacaaa accagtagat atgtctttat ctgaaaaaaa aatagatgaa gtgatggctt
      601 catttattgg tgagatcacc cagataccac caatgtactc agcggtaaaa gtcaacggta
      661 agcggttata tgaatatgcc cgcaataatg aaacagtgga gcgtcctgtt agaaaggctc
      721 agatttaccg ttttatccgg acaagtgaat tgacaagaga cgaagtgaca ggaaccattt
      781 cttggcgctt cgaagtagaa tgcgggaaag gaacctatgt ccgcacatta gctgtagata
      841 caggcaagaa acttggttac cctgcgcaca tgtctgatct gacccgaaca gcaagtgccg
      901 gtatgtccca gaaggatgct ctgacattag aagaagtagc tcaagctgtg aaaaatggga
      961 caatcgatga ttgtttgctg ccaatagaaa aaggagtgga acggttcaaa cgagtagata
     1021 ttactgatga agtatggcag aaagtaaaaa acggtatgag acttgattat actgtatttg
     1081 cgctcccaga aatgccgtca gaagaaattg ctttgtttta taaaggaaaa gttgtcagta
     1141 tttatcagcc aaacccgaaa gaaaaaaaca aattaaaacc tagtaaagta ttgagaaatg
     1201 aggaataacg aatgaatatc atcaagatca gacatcctta ccaatcagaa caaattccag
     1261 aagacgatgt cgttttagtg ctgggatttt tcgacggcgt gcatatcgga caccagaaag
     1321 tcataaagac aggtatggaa attgcacaaa aagaaggatt gaaattagca ttgatgactt
     1381 tcaatcagca tccatctatt gtctttaaaa agatcgatcc tagcagcgtg aaatatttga
     1441 ctagccttaa gcaaaaagaa gaaaaaatgg ccgctttggg tatagattat ttatatgaag
     1501 ttgattttac ttcttctttt gctcatttag caccgcagga atttgttgat caatacatcg
     1561 tagggttaca tgcaaaatat gctgtttccg gttttgatta tacgtatgga ccaaaagaca
     1621 ttgcagatgt cgctcatttt cctgaatatg ccaaaggaag attcaaaatc gtcacagttt
     1681 ctaaagaaga acaaggtgaa aaaatcagct ctacccgtat tcgtggatta ctagacagcg
     1741 gacaagtaaa agaagcagca aaactattag gttgcacata tgaggtagaa ggggtagttg
     1801 tccatggcga tgcacgaggc agactactag gattccctac agcaaatgtc aaagtaaaga
     1861 gcacggttca tttgcctaaa gaaggtgttt atgtgtcgga aataaaaatt ggggaaacat
     1921 ggtatccagc catgggttca attggacata atgatacatt cggtgaagga cgggagctga
     1981 ctgtagagtt gtatattttg gactttaatc aagatatcta tggtgaacat gtcgcggtac
     2041 gctggaatca atttttaaga gatcaagtga aattttctag tgtagaggaa ttgattgaac
     2101 aactcaagga ggatgaacaa gcaacagctg aatatttttc tcagcaataa aacattatgc
     2161 ataaaatctc ttgtttatgt ataactagca attacaataa aatgggtgat aaataagccc
     2221 aggaaagggg ctgtgacaaa agtcttgtca cagccttttt ttccaaataa atggtttttc
     2281 agaagtagct tcttcggaaa taagccgaaa tttcttgaag ctgaccactt ctgtcacaac
     2341 ctctttcttt atagaaataa aaggacacta gcaattcatg aaaacgattg ctagagcgta
     2401 tcatttgctt tagactatat atcttggtgt acactcactt taaggcggaa ataaaagtta
     2461 tccgtaataa caggtttagg tatgaaaaag gagtgggtac tatgtacaag gaattagaaa
     2521 acaaagtcgc agtagtaact ggtggctcaa aggggattgg aacagcgatt gctcaacgat
     2581 tcgggaaaga aaaaatgaat gtagttgtca actataactc ggataaagaa ggagcagaaa
     2641 aagcagtcaa agcaatcgaa gaggcaggcg gaaaagcagt ctctgtacaa gcagatgtca
     2701 gttctgaaga aggaatacag cgtttacttg atacggcttt agaaaatttt gggacactgg
     2761 acgtttgggt taataatgct gggatggaaa atcagcatcc aacccatgaa cttagccttg
     2821 aagattggga aagagtgtta aaagtcaatt tgactggcgt ttttatcgga acgaaagcgg
     2881 ctttaaatta ctttacagag aataataaaa aaggaaatat catcaatatg tcttctgttc
     2941 atgaacagat cccatggcca acgtttgctc attacgctgc ttcaaaaggc ggggtaaaat
     3001 tatttaccga aacggtagca atggagtatg caccgaaggg aatcagaatc aatagtatag
     3061 gccctggtgc tatccgtaca cctattaatg cggcaaaatt tgatgatcct gaacaaaaag
     3121 aactcttgga aagtatgatc ccactaggac gcgtaggtga accaaaagaa atagcggcga
     3181 cagctgcatg gttggcttca gacgaatcca gttatgttac aggtattaca ctatttgcag
     3241 atggtgggat gactttatat ccttctttcc aaggtggaaa aggataaggg tgaataaaaa
     3301 tgggtttatt gattgcattg atcccggcag ttggctgggg gatccagcca ctgattttga
     3361 aaaagattgg tggcagacca acaaatgaga tattaggaac tggtattgga gcggtgcttg
     3421 tcggcttact cgttcaatta ttcgcttctc cagctggtat ttcagtgact acatttttga
     3481 ttagtttact ttctggtgca ttttgggtta ttggacaaac aggacagtat acatctttca
     3541 acttgattgg tgtttctaaa acgatgccaa tttcgactgc attacagtta gtcggaacct
     3601 cgttgattgg tgtcttcgct tttggagaat ggtctggaag tatggggaaa atcattggag
     3661 cagcagcaat cattcttctt gtatttggtt ctgctttaac ggcaatcagt gatgatcctg
     3721 gaaaaaaagg cggtatcaca aaaggaatta gtctattagc atcaacaagt attggttatt
     3781 gggtatacag tgcattgcct aaactagttg atgcaagcgg actttccatt ttctttccgc
     3841 aaatgatcgg tgtcttttta ggggcagtga tttatgtgat tttccgtaaa ccaaccgcat
     3901 tttctgaaga caagagttgg aaagcaacga tcgttggagc catctttagt gtgtcagcat
     3961 tggcttatat tttttcagca aatgaaaatg gggttgctac tgcatatatc attacacagc
     4021 taaacgtagt tatctctaca ttaggcggta tgtacatcct gcatgaaaat aagacaccaa
     4081 aagaaaaaaa attaacgatt atcggattat tgctgatcgt agtaggaagc atggtcacgg
     4141 tctttatttg aggataaaga tggtaaaatt tcatttatta aaaaaatatt tgtttgaacc
     4201 aaacagtaag tacttataaa aaaatagcgc tagaatttcc aacatctctg gaatttctag
     4261 cgctttttaa ttgtttaaga tacaagggaa atatctgtct ggatcaataa tttttcattg
     4321 atccattgac taaagtttac gacataattg aagttaccac cgattagtat ctccgcatga
     4381 ttgtctttat aaagatcgta ttgtaaaaga cggtcttttt tatttgcgta aacatcgtta
     4441 tggtactgga ctaattgttc tcggaattga ttgattgctg taaaatcacg atattgaagg
     4501 ttgaaacgca tcgtgattgg tgcatttagc atgaatcgct gcatttcttt tgctgcttcc
     4561 tctgcttgat ctccgtatag gaactcaaaa agattacgtt cagaaaattt ccattgcccg
     4621 ccaacctttg ttccttttag ttttccttca tgaagataat ttctgataga acgtgtagta
     4681 acacctaatt gttcggctaa ttcatttact gagtaaaaat ctttcaatgt tcaccctcct
     4741 atgtgaatgg ttctactgac ttagttgata tttgcttaat cacgaaatgt agaaagaacg
     4801 attttaatta aggtcattgt aaaaatcaag tcagaaaatt ctaactttta tttctctaaa
     4861 gaaattcgtt ctctcctaaa gtgatattat atttaaatat acctgaaaat aatgggcagt
     4921 attatgaaag atcactgata ttttctcgta ttttttcctt attcaaaagt tttgcaggaa
     4981 aattgctgaa aaaataattt tactaagtag aaaattcaaa gccattcaat cagtgatttt
     5041 tttcagcaca agaaagactc cttataaaaa tagcagatac tttgtcaatt aagtgtttaa
     5101 ccagggatga taaaaaggat aggattgaac aaaacctgta taaggtgatg aatagtttcc
     5161 tcgccagtaa aaggtttatt cgtataaagc tttatcgcca aaatttatca tgaccttttt
     5221 tatcttcaat attaaatgaa atcaattgtt caatcaattc ccagttgatt acacttttcc
     5281 aaggaacttt gatgacgtta tccgtatata cgtagcctgc ttcttggata tttttttcaa
     5341 gggcacgaat cgctgctttt tccggtgcga tagaaaaatg atttttagca aaactaaatg
     5401 caataataaa ggtaccatgg tcagtaaaca taggttggtt ccattttaca gttgtgtcta
     5461 gctggggata cgtttctgtt atcttagcaa aaaggtcttt gatcttttgt tgatgttctt
     5521 tttctttgat ttgattgatg atcggctgaa atttttccat tctaaaacgc ctccattaag
     5581 tggtttgatt tattttacca gaaaaacaat agttatgtat aaaaaacgaa caaaacacaa
     5641 gtaatgttgt aaccgctata tttatatgat aagatgtctc aaataataaa atagaaaaga
     5701 gacataaaaa tgattgactt ggcaaagaaa ttcttacacg aaaatatata ttttgagttg
     5761 tatcatcatc gagccattta tacaaatgaa gatgctttgg taataaagaa agaacaagga
     5821 tttacaggta cagagaccaa aagcttattc ttaaaagata aaaaagataa taactacgta
     5881 tatctgactt ttactacgaa acaaacggat ttcaaagcat tagggaagat cgtcggtaaa
     5941 aggctttcta ttgtttcatc agaacgcatg gaagaacaaa cgggacaaaa gcagggcgct
     6001 gtttctccgt ttggttatga aaaacagatt ccgattatta ttgatgaaga gctcttatca
     6061 aatgaaaaac ttgtttttgc accaggtaga ccagatcaaa cgatggtcat ccaaacggtt
     6121 gacttaaaca aaatcatcca gctacttgag atgccgatat ttttgatgcc ggcaaacgaa
     6181 aaaaacaatt aaccaagtaa aatagtgcat acttggaggt gaagcaacat gataagttat
     6241 ccattattag aaagaaatgc aacgattggg gttactgcac catcctcagg cgtatcagag
     6301 gaacaccatt cgttactcga atcagcttta aagagaatgg aagaaaaatc tttccaagta
     6361 gttactggaa agacgctttg gacgcaagat aaggaaaaat caggtccagc aagaaaacga
     6421 gcagatgaat tcaatcaaat gatgcaagat gaaaatatcc aaatgatctt tccgacttgg
     6481 ggaggagaat tattgattga gattctcgat tttgtcgatt ttgatgctct acaaccaaaa
     6541 tggatagtag gttattcaga tattagtacg ttgctacttg ctgtcacatt aaaaacaggg
     6601 atagccactg cacatggaac taaccttatt gatttaagag gagagtactt ggatgaaacg
     6661 acagcaatgt gggaaagtgt actgaaaaca agagaaggag aatcgattct acagcaatct
     6721 tctgaaaagt atcaaaaagt gtggccccat gagcattcat catcttctgt tttccatctc
     6781 actgaaccaa caaattggca atcagtcagc ggagatgcag taaggatgaa gggacgatta
     6841 ttaggtggtt gtattgatac gatcaggcat ttaatcggta ctccttatgg agatgtccaa
     6901 tcttttaaaa gaaagtataa tgatggaaag ccgatcttgt ggtttctaga aaactgtgag
     6961 ctatcgtcag ttgatttaag aagatcactt gttcagatga aactggcagg ctggtttgat
     7021 ggcagctcgg ggatcatgtt cggtagaagt gcggcagagg atttgttaga ttataaaatg
     7081 aaggatgtat acgaagatct gtcaaaggaa ttaaaactac cgatcttgta tgatattgat
     7141 tgtggtcatg taccgccaca actgacattg attaatggtg cctatgcaga agtagcggta
     7201 gaagatagaa aagcgactgt tttgcaaacg tttatttaaa aaattttttc ctgccttgga
     7261 gtctatcaaa gaccaataaa tctaaataga aaagaaagtg aaagaagctg acaaaatgct
     7321 gtcagcttct ttttgtataa catattagaa agtctaatta tctataactg tcacatcgat
     7381 taactgtttc acgtcattgg gatttcctgt aggaatagct actacagatg cattatcaat
     7441 gatttcttga gttgtttctc taatgaacgc tggataagat gtttgatctg caggcatttg
     7501 ccaatgtgaa ggaactggat aactagtgat tgtcccgtca tggttacttg aatacactaa
     7561 aactccctgg taactgtatt tcccagtgag cataaccaca tctttcggat agactgcact
     7621 ccctgcatca taaggggcga taggtgttcc tgcaggataa tgaataacat gtaattcgaa
     7681 atcacccgat gtatctctaa aagtattacc tctaatagct agccaaacac gtgcgtactc
     7741 aatttgtaga tcagaatatc ctgctaacgg atctattgac tgagaagact gtgaggaggt
     7801 tgtgtctatt gttgaagaag aaatatttgt ctcaactgta ctactagatg tagaagaagt
     7861 attgggctct gagactttac tgcttgttga agatgtattc gtttcagtag aagctgattt
     7921 ctgagtactt gatttttcag ctgaactggt ttgtctgatt gaacttttgt ctgtggtcgc
     7981 agatggatca ctattttctt tactaggaga cgtacatcct acaaggaata aagagaccaa
     8041 caataaaata aaacctaact ttttcatata aaatacctca ttattttttt aataccagta
     8101 tagcataatc ctgaattttt gaatccgtaa aaccttgtct atgaatataa atagagtgta
     8161 tcttctttga taaatgtcag aaaaagtgtg acaaataatc atcagtaaaa ttacttgtca
     8221 cactattgat aaggagtatt taattgaaga gaatgattag gagaaaggat ctccgtactt
     8281 tttatagtaa tcatagaatc caagtttgta tagacgaatc gttttttctc ttatttcttc
     8341 tgtttcaaaa tggactgctt gaagaatcaa gtctgtgaat tctataggag ctgttccatt
     8401 cgcagtaatc aaattacgat ctttcacagc ttgttgttct ataaaatctt ctttattctg
     8461 ataattttcc gattctaacc aaggaaattg cgcatttccg gtgtgtttgt aaccttgcaa
     8521 taatccgctc tgagctaaat aatcaactgc cccacaaata gcagctactg gtacgtctgt
     8581 ttttaacaat ttatcgatta tttgatataa atgatgattt tttatgtccc atgaattgcc
     8641 accgatcata ataaaaaggt caactttttc aggtatttgt tcgattaagt aatcgatttt
     8701 tgtttttaat cctccaatgg aagtgacctc tgattggata gaagcagttt tgttttgcca
     8761 tttctcattt tggtttagtg tgctagtaat ataagcacct tcccaatcgg catattcctc
     8821 taatagaaac gtaatcgcag ttttcatttt caagctctcc tttactatct ataacaagga
     8881 caacagtttt aacctacaga cattcattaa aattgggtag cgacagcgaa aacaacaatt
     8941 cttaagtttt agacagagta tacagatagt caacttaatt aaatacgaac taaataaaaa
     9001 tgacaggtaa tcatttttgt ttaccagcat tataacattt tgcatacatg gatgacaaaa
     9061 gaaccaattc ccacttgctt gagtacaata ttaaaagaaa ctggaaggca aaaagtaatt
     9121 atagaaacga aaaataaatc atatcgggca ctcagacatg aaaacaaccc tagagatata
     9181 taactaggta accagtttaa tgaaagaaaa aatcatccaa gaagtcgatt cttggatttt
     9241 ttagtggatt tgttcgccaa atacgtttag tatgcgtata tgagaggttg taagcaaagc
     9301 gttgtggtct gagcacttaa ggaggaatct gtgaaaatag cttttcatat ttttgcagat
     9361 tttgacttaa tgccgaaggt cagctttgcg attaccgttt atcgagaggc tgtaaaagca
     9421 ccgtgtagct ccgatgacaa taagcaagca tttttagagc taggtttcct tgattctaaa
     9481 tatgcggctt atttcaatga gttggtgctt gaacgcgatt ttaagaaggt cgaaaacagg
     9541 cacgactttt cgacgtaagg agaaagaatt tcaatgatag aaacaataaa tcccgcagaa
     9601 aacaaggttt ctgcgtacat tcatatccca ttttgcgagc atatctgcta ttactgtgat
     9661 tttaataaag tttttttaga agggcagcca gtagatgagt atgtggaaat gctgctgaat
     9721 gaaatgaaaa taatgctaga aagtcatccg acagcgaatt tagaaacact ttacgtaggg
     9781 ggcgggacac caacttcttt atctgctaaa caacttgatc gactgttatc aggtgctaga
     9841 gagatcctgc cttttcaaaa tggtaatgag tttactgtag aagcgaatcc aggtgatttg
     9901 acccgtgaaa aacttcaagt aatgaaaaac tatggcgtca atcgtttatc catgggagtg
     9961 cagacatttg ataatcgctt attgaaaaaa attggacgta aacacaccgc agaagatgtg
    10021 tatcaaacta tgcaattttt agaagcagaa aattttacca atgtaagcat cgatttgatt
    10081 tatgcattac cgggacaaac actagaagga tatctggata ctttggaaaa agctttggct
    10141 ttggatctgc ctcactattc tttgtactca ttgatcctcg aaaacaaaac aatgttcatg
    10201 aactgggtac gacaaggaag actcgaactg cctgatcagg aaacggaaac cagaatgttt
    10261 gaagagacga ttgaagcaat ggaaaagcat ggacgtcacc aatatgaaat aagtaacttt
    10321 gggctctccg gacatgaatc tcaacataac ctcatgtact ggaacaatga ccactatttt
    10381 gggtttggag ctggtgctag cggttatctt ggagatattc gttaccgcaa caaaggacca
    10441 atccaacact atttacgccc attacgagca aatgaacgcc cggtattgga agaagaaaaa
    10501 ttgacacgaa aaaatcaaat agaagaagaa atgttcttag gactaagaaa aaaaacaggg
    10561 attactaaaa aacatttcta tgatcgctat caaaaaacaa ttgaatcggt gtacggtgat
    10621 gtgctaaggg aattagagca agaagggtta cttgttaatg aagaagaccg tgtttatttg
    10681 acaccaagag ggaccttttt ggggaacaat gtgtttgagc gctttttgtt tgaaaaatag
    10741 tttaaagaat atttgttttt tatctgaatt taaataaaaa aagttcaaaa atacaataaa
    10801 ggactattga aacgttgata taactggatt tacatcaatt atttagaatt agcactcttg
    10861 tgtttagagt gctaaaaaat ggagtctttc tcttgacagg agaagggctt cttgctatat
    10921 ttataagtgg attagcactt agaatatatg agtgctaatg agaggtgagg aagatgttaa
    10981 caaagcgaca aaacgacatt ttacgtctga tcatccaaca ctatacgagt agtggcgtgc
    11041 ccgttggttc caaaacattg atgtctgagg gagtcaaggc cagctcagca acgattcgca
    11101 atgatatgaa agcattagaa gatgaaggat tgctgttgaa gactcactct tcttctgggc
    11161 ggattccatc tgctttaggc tatcgttatt acgtggatca tttgttaaaa cctgctcgcg
    11221 tagcagaaga tgatttgctg ctgattcgtc agtctctagg cagagaattt catgaaatca
    11281 atgagattat taagcaatct gctgagatat tatctgagct gacaagctat acgacttttt
    11341 cattgggacc tgaaataaaa gaccgccgac tgactggctt tcgtatcgta cccttgaata
    11401 atcgacagat tattgctatc gtcgtaacag atatggggaa tgtagaaagc caagtgttca
    11461 ctcttcccga atatatggga agtcaggaac tagaaaaaat ggtacagatt gtaaacgacc
    11521 gtctagtcgg agatcctctg atgacggtgt accataaact tcgtacggag attccgatga
    11581 ttcttcataa atatttccaa acgacagaag ggatgtctca gttatttgac accgttcttg
    11641 gtcatgtttt tgaagataag gtttatgtca gtggacaaat gaatctcttg gattatgagc
    11701 cccgtcaaga tcttgatcag ttcaaatcga tgttttcttt tatgaaagac tcagacggac
    11761 ttacacaaat gatcactccg atggatagca atattcatat caagattggt gctgaattag
    11821 gcaatgattt attgcagaat atgagtatga ttcaagcaag ttacgagata gatggtcatg
    11881 gaagaggtac aatagccttg ttagggccta ctagtatgcc ttattctcgg atgttcggtc
    11941 tagtcgatgt ttatcgaaga gaactagcag ctaaacttgc tgattactac cgttcgcttg
    12001 acttgtcaaa ctcgtaatgt gaataacgaa gctatttgca gctgatcgtt ctctctttct
    12061 tagtaagagc aatcaaacag ctgactgaat aatgaaagga agactgtatc gtgaaagaaa
    12121 atcaagaaga actagataaa gaaatgacag atgctcagcc agaaccggaa atcgatgtcg
    12181 aagctgcaga agattcgggt atttcagaag ctgaagcgga agaattcgaa acagcgaaat
    12241 taaaagctga gttagaagaa atggaagata aatacttgcg ggctcgtgct gaaatcgcaa
    12301 atatggcaaa tcgaggaaaa aatgagcgtg agcaattaca aaaataccgt tcacaagatt
    12361 tagccaaaaa attacttcca tcaattgaca acctggaacg tgcattagcc acagaagtgt
    12421 cagatgatca aggggcaggt ttgaaaaaag gcgtggaaat ggtcttggaa agtttgcgta
    12481 acgcactgga agaagaagga attgaaaaaa tccctgctaa aggagaagcc tttgatccta
    12541 atcttcatca agcagtacaa actgttccag cgactgaaga tacaccagcc gatacgattg
    12601 tagaagtact acaagaaggc tacaaattac atgatcgcgt gttaagacca accatggtca
    12661 ttgttgcaca ataattgtgc ggatataaaa cttacacttt caattaaaga aggagacgtt
    12721 aattatgagt aaaattatcg gtattgactt aggtacgact aactctgcag tagcagtatt
    12781 ggaaggaaac gaagcaaaaa tcatcgctaa cccagaagga aaccgtacaa caccttctgt
    12841 tgtatcattc aaaaatggag aaatccaagt aggggaagtt gcaaaacgtc aagctgtgac
    12901 aaacccaaat acgatttcat caatcaaacg ccatatcggt gaagcaggtt acaaagtaga
    12961 tgtagaaggt aaatcatata caccacaaga aatctcagca atgatccttc aatatatcaa
    13021 aggattcgca gaagactatt taggtgaaaa agtcgaaaaa gcagttatca ctgtgccagc
    13081 ttactttaat gatgcacaac gtcaagcaac aaaagatgct ggtaagatcg ctggtctaga
    13141 agtagaacgt atcgtcaatg aaccaactgc agctgctctt gcctatggtt tagataaaac
    13201 agatcgcgac gaaaaaatct tagtattcga ccttggtggc ggtacttttg acgtatctat
    13261 ccttgaacta ggagacggtg tctttgatgt attgtcaaca gctggcgaca accatctagg
    13321 tggggacgac tttgataaca aaatcatcga ctacatggta gcagaattca aaaaagaaaa
    13381 cagcattgac ttgtctcaag acaaaatggc tttacaacgc ttgaaagacg ctgctgaaaa
    13441 agcgaaaaaa gatttatctg gcgtatcaag cacacaaatc agcttgccat ttatcacagc
    13501 aggagaatct ggaccattgc atttggaaat gacattgaca cgtgcaaaat ttgatgaatt
    13561 aacagctgac ttagtagaac gtacaaaagt accagtacgt caagcgctaa aagatgcagg
    13621 tttatcacaa tcagaaatcg acgaagttat tttagtcggt ggatctactc gtatccctgc
    13681 agttgtagaa gcagtacgta aagaaacagg aaaagaacca aacaaatcag ttaaccctga
    13741 tgaagtagtt gctatgggtg ctgctatcca aggtggcgtg atcactggtg atgtgaaaga
    13801 tgttgtttta cttgacgtta caccattgtc attaggtatc gaaacaatgg gtggagtgtt
    13861 cactaaattg attgaccgca atacaacgat tccaacaagt aaatcacaag tattctcaac
    13921 tgcggcagat aatcaaccag cagtagacat ccatgtatta caaggtgaac gcccaatggc
    13981 tgctgacaac aaaactctag gaagattcca attgacagat attccagcag ctcctcgtgg
    14041 tattccacaa atcgaagtaa cattcgatat tgataaaaac gggattgtaa atgtatctgc
    14101 gaaagatcta ggtacacaaa aagaacaaaa aatcacgatc aaatcttctt caggtctaac
    14161 agacgaagaa atcgaacgta tggtaaaaga tgcagaagca aatgcagaag cagataaagc
    14221 tcgtaaagag gaagttgacc tacgtaatga tgtagatgca ttgctattct ctgtggacaa
    14281 aacattgaaa gaattagaag gcaaagtgga cgaagaagaa gtgaaaaaag cagaaacagc
    14341 tcgcgatgaa ttgaaagccg ctgttgaagc aaacaacatc gaagaaatga aaactaaacg
    14401 cgatgcattg aacgaaatcg ttcaaaactt gactgttaaa ctatacgaac aagcggcaca
    14461 acaacaagct caagaaaacc cagaagcagc tcaaggcgga gcagatgatg tcgttgatgc
    14521 tgattttgaa gaagtcgatg gcgacgataa ataatcagtt cactgaattt cgagagaagg
    14581 ccaaagttgc tactttggct ttttcttttg aaaaatagtt tgaagtatcg gtttttgttt
    14641 caaacaaaat atgatatgat aacaagcgac gtgaaaatga tgagaaccaa taggaggaaa
    14701 gcctatggca acaaaacgtg attattatga agtcttaggg ctctcaaaag gagcatcaga
    14761 agatgaaata aagaaagctt atcgtaagct ttcgaaaaaa taccatcctg acatcaataa
    14821 agaacctgat gcggaagaaa aattcaaaga agtatcagaa gcatatgaga ttttaagtga
    14881 cccgcaaaaa cgcgctgcat atgaccaata cgggcatgca ggcacagatc caaattacgg
    14941 tgctggtgga gctggtggcg gatttggtgg attcggcggc ttctctggtg gcggcttcgg
    15001 tggttttgaa gatatcttcg actctttctt tggaggaggc ggtcggtcag tcgatccaaa
    15061 tgcgcctcgt caaggtgctg atttgcaata tacggtcgac ttgtcttttg aagaagcgat
    15121 ttttggtgta gaaaaagaaa tcaagtataa tcgggaagaa atctgtcata cttgtggtgg
    15181 gaacggtgca aaaccaggca cacaaccaac tacttgtcat aaatgtcatg gtgcaggtac
    15241 gattaatgta gaacgccaaa caccacttgg acgagtgatg agccgtcaaa cttgtgatgt
    15301 ttgtcatggg acagggaaag aaatcaaaga accttgtcca acctgtcatg gctcaggaca
    15361 tgagaagaaa gcacattcag ttaaagtgaa tgtaccagct ggtgtagaag aaggacaaca
    15421 aatgcgttta gctggtcaag gagaagctgg agaaaacggc ggaccatttg gtgatttgta
    15481 tgtggtcttc cgtgtagaag aaagtgatat ctttgatcgt gaaggttctg aaatttacta
    15541 tgaattgcct ttaagttttg tacaagcagc tttgggggat gaagtccaag taccaactgt
    15601 ccatggagat gtgaaattga agatccctgc tggaacacag acaggtacga acttccgttt
    15661 acgtggaaaa ggcgctccga agttacgtgg tggtgcaaca ggcgaccaac atgtcaaagt
    15721 aaaactgatc acaccgaaaa atctaaatga acaacaaaga gaagcattac gtgcattcgc
    15781 tgaagctggc ggcatcaaag ttgaagaaca gcaagaagac ggtttcttcg ataagtttaa
    15841 agatgctttt ggcgggaaaa agcggaagta gtttttctag taaaaacgct aagtcattaa
    15901 taattaaaaa ccagacgaac aatcatatgt tcgcctggtt tttttgtagt tgtcatgttt
    15961 gtaccaacaa aaaagccagc tttagaatat gataatcgtc atagtttcta ggggtataac
    16021 cagtgagaga atggaacttg ttcaatcgat attgcaaggt gtttttatga ataaataatt
    16081 cttctgagca atttttgatg cttccgttat ttttactgaa gcatgccaaa gtcttcttga
    16141 acaaatgtac ttcttcttct gtcaggcttt tcaaaatacg ttttacatat aatgttcgtt
    16201 gatctgacgg gattgctggt aaaacgatcc cgaggtctaa atcttcaaaa aagcggatct
    16261 cgttcacaga ttgatggaaa gctatccatt cgcaaacttg tttggcatga aggaaagatt
    16321 gcggtgtctc ttgctctgta taacaaagcg acccaattcc aaagtttagc tgtaactgat
    16381 acattttatt aaactttgtc tggattttat caagcaatga tagcaatgag gctctggaaa
    16441 tccgattgac taggataatg atttgttgtc tatgtacagt gagcaaagcc tgtccgtaat
    16501 aagagaagac cctttcgagc aactccaata aaggattgat ccgttcttga cacaattgct
    16561 gattgtcaga aagttgtccc acaactacat aatatggaga agaaaaatca agctcaatta
    16621 agtgagggtg gtatcgacta tgtacttgat atcatcaatg aaccgatggt actttcttat
    16681 gcgatggaac aggtagagcg attgcttgtt tgtgcaggaa aacaagcgat gcggctgata
    16741 cgattaggtg agaaaataag aagataaaaa tacacggtcc cttcatggcg accgtgcatt
    16801 tttggttttt attaaatatt taatacttta ttcaagaaat cttttgtccg ttcattttgc
    16861 ggattttcaa agatttgttg aggcgttcca tcttctaaaa agtttccgtc gtcaatgaac
    16921 atgacgcgat tggccacttc tttagcgaac cccatttcgt gcgtaacgat aaccatcgtc
    16981 ataccttgtt ctgctaactt tttcatgacg ttcaagacat caccgaccat ttcaggatcg
    17041 agtgcagaag taggctcatc aaaaagcatg atgtcagggt tcatcgctag agcacgagca
    17101 atagccacac gctgtttttg tccaccagaa agcatttcag gatacatatc ttttttatct
    17161 tctagaccaa ctgtctgcag taatttgatt gcttttttct ctgcttcttc tctagattct
    17221 ttcttcaggt ccatcggtgc taaaatgatg ttttccaaaa tagaaagatg agggaatagg
    17281 ttaaagtgtt ggaataccat tccgatatgt tgtctcacca agttgatatc tgtgctttta
    17341 tccatcaagt gggcgccgtc aataataatt tcaccgtcag aaggttcttc taaacgattc
    17401 aagcaacgca agaatgtact ttttcctgaa cctgaagggc caatgataca gacgacatct
    17461 ccttcgttga tggatacatt gatgtcgttt aatactgtgt tatcgccgta ttttttgact
    17521 aaatgctcaa ctaagatttt ttctgccatc ttacttcacc ttcttttcta aaacttttgc
    17581 taattttgtc aatgctgtga tcaaaatcaa gtacatgatc gcaatgatca agtaaacata
    17641 cgtactttgt gttgtacgtg caacaatgat cttaccagtt tgcagcaatt cgactacacc
    17701 gattgcggaa atgatcgttg tgtcttttaa tgagataacg aactgattga cgaatgatgg
    17761 gatcatgatg cgtatcgctt gcggcaaaat gattttttgc attgtccgat tataagaaag
    17821 acctaaactt ctggaagctt ccatttgtcc gacaggaacg gcgttgatcc cgcctcgaac
    17881 aatctctgcg atataagcac ttgcgttaag agtcaaggtg ataacaccag caaggaagtc
    17941 aggaatcgta aatccaacga taccaggcaa cccaaagaaa ataaagaacg caagaaccat
    18001 cattggaatt cctcggatga tatcgacata aatactagca attgtgcgaa gagcgcgtat
    18061 tggtgctaca ctgaataatc caaaaatcac accgattact atagccaaag caaaggagat
    18121 caaagttagg agaattgttc tccaaagtcc tttcaacaat gcttgatagt tgttttggat
    18181 aagtccaaga aatgttgatt catcagcagt ggaagactca ctggaagttt ctgaaccatc
    18241 cgctacatat tctttaataa tcttatcgta ttcgcctgtt ctttttaatt ctttcaatcc
    18301 ttcattgaac atattaagaa gctcaggatt ttgtcctttt ttaacggcaa atgcatattt
    18361 tccgccagat tcttttttga tcggtgtttc caattcttgt ccttgtttga tcgcataacc
    18421 gattaccgga taatcatcca tcattgcatc gattgcgcca acttttaacc cgtcgtacaa
    18481 ttgatcagca gcatcaaaat atttgataga atagccatat tcagattcat ggtcgcttaa
    18541 aaattcagca ctttcggtac caacttttgc tccgactgtt tttcctttca aatcttcata
    18601 agacttgatc gaagtatctc cttttttgac agctaattgg atcccgctat caaagtaaga
    18661 atcagaaaaa tcatagcttt tctttcgttc atctgttaca gtcattccgg caatcattcc
    18721 gtctgcttgt cctgattcca aagcttgcaa agcagcagag aaaccacggt agtccattcg
    18781 gatgttaaat ccttgcagtt tggcgatgtt ttccatcaat tttacatcga tgccttcgta
    18841 ctcgcccttt gcgttttgaa attcaaatgg agcaaaagca gagtcactgg caattacgta
    18901 tacgtctttt ttgggctcta ttttttgcat tgtctcgctt gtgcttgact ctgccgttgt
    18961 agtgttgtca gcttgtgcaa catgaccaaa cgcaagtgtc acaagtcctg tcattaagaa
    19021 aacaaatgag tgaaataaat gctttctttt cataatcaac ctcctaaatt tccaatattt
    19081 tattattata ggcgaaaagt gctgaatcag acaagactgt aagctcgaaa aaatgaaaaa
    19141 aatgcgagtt tctaacattt tatgttataa aacataacat gtataataag ataaaaaagt
    19201 ggcgaaagta tgttcggtgt ggtataattt tttagtaagg aatgcctttg ctttcctttt
    19261 ctttttattg gtcgtaaaat gaaaaggaat gaatgaaaag gaggacgaag aatgattgag
    19321 agagatacct cccgacactt tgagcttgtc tcgaaatacc aaccggctgg tgatcagcct
    19381 gaagcgatta accaattagt ggatggcgta gtcggcggga aaaaagcaca aatcttatta
    19441 ggtgcgactg gaacagggaa aacatatacg atttccaatc ttattgagaa agtgaataaa
    19501 ccaacactga ttattgccca taacaaaaca ttggctggtc agctgtacgg ggaattcaag
    19561 gaatttttcc ctaacaatgc tgttgaatat tttgtttctt attatgatta ttatcagcct
    19621 gaagcttatg tgccttcaag cgatacgtat atcgaaaaag attcaagtgt aaatgatgag
    19681 atcgacaaat tacgacattc ggctactagt tcattattag aaagaaatga tgtgatcgtc
    19741 attgcatccg tttcatgtat ttttggatta ggctcgcctt ttgagtacca aaaacaagta
    19801 gtttcgattc gacagggagc agaactagat cgcaatcagt tgattcgtga cttagtcagt
    19861 atccaattcg aaagaaatga tatagatttt cagcgcggtc gttttcgagt gcgcggtgat
    19921 gtcgtggaga tttttccggc ttcaagagat gaacgtgcct tacgtgtgga gttttttgga
    19981 gatgaggtcg aacgtatccg agaagtcaat gcactgacag gtgaagtttt aggagaaacg
    20041 gaacacgtag caatcttccc ggcgactcac tttgtgacga atgatgaaca tatggagcat
    20101 gccgtagcga atatcaaaga ggaattagaa cagcgtttaa ctgtcttgcg aaatgaaaac
    20161 aaacttctgg aagctcaacg tttagaacag cgaaccaatt acgatattga aatgatgtta
    20221 gaaatgggct acacgtcggg aattgaaaat tattctcggc atatggacgg acgtaaagaa
    20281 ggtgaaccgc cttatacgct attggatttc tttcctgaag attttttgat cgtggcggac
    20341 gaatcgcacg taaccatgcc tcaaatcaga ggaatgtata atggtgaccg agcgagaaaa
    20401 cagatgctag tagattacgg tttccgtttg ccatctgctt tagacaatcg gccacttcgg
    20461 ttagaagagt ttgaaaaaca tgtcaatcag atcatttatg tctctgcgac gccaggacca
    20521 tatgaacatg aacaaacaga taccgttatc caacaaatca tccgtccgac agggctgctt
    20581 gacccagtga tcgaagttcg tccaatcatg ggacaaatcg atgatctagt aggcgaaata
    20641 aatgaacgag tcgaaaaaga ccagcgggtg tttgtaacga cattgacgaa aaaaatggca
    20701 gaagacctca cagattattt caaagaatta gggatcaaag tcaaatattt gcatagtgat
    20761 atcaaaacgc tggaacgaac agaaatcatt cgagatcttc gattaggtga atttgatgtg
    20821 ttagttggaa tcaatttgct tcgtgaagga ttagacgtac ctgaagtttc ccttgttgct
    20881 atcttggatg cggataaaga aggcttttta cgtagtgaac gttccttagt ccaaacgatt
    20941 ggacgagctg ctcggaatga agaaggtaaa gtaatcatgt acgcagacaa agtaacagat
    21001 tctatgcgtc tagcgatgga tgaaacgtca agacgtcgta cgattcagca gaagtacaat
    21061 gaagaacatg ggatcgttcc aaaaacgatc attaaagaaa tccgagattt gatttctatt
    21121 acgaaagaat cggaagatga tacaaaagaa gcggtacaag tctcgtacga agaaatgacg
    21181 aaggaagaaa aagacacgtt attgatgaaa ttagaaaaag aaatgaaaga tgcggcaaaa
    21241 gctttggatt ttgaaacagc cgcgaatgtg cgagatatga ttttagaatt aaaagcttca
    21301 aagtaggagg acaacatggc taacgataaa attacgattc atggtgcacg tgcccataac
    21361 ttgaaaaata tagatgtaac gattccacga gataaattcg tggtcgttac aggtttgtcc
    21421 ggttctggaa aaagttccct agcatttgat acgctgtacg ctgaagggca gcggagatac
    21481 gtagagagcc tttctgctta tgctcgtcag tttttaggac aaatggataa gccggacgta
    21541 gatagcatcg acggattgag tccggcgatt tctattgatc agaaaacaac aagtaaaaat
    21601 cctcggtcga cagtaggtac tgtgacggaa atcaatgact atttacgctt gttgtttgca
    21661 cgtgtaggac atccgatttg tcccaacgat catatcgaga ttaccagtca atcagtagat
    21721 caaatggcag atcaagtaat ggctttgcct gagcgcacaa agatccaagt gttggcaccg
    21781 atcgtggtaa agaaaaaagg acaacataaa aaaatattcg aacgaatcca aaaagaggga
    21841 tacgtccgcg ttcgagtcga tggtgagatc tatgatttaa gtgaagtgcc tgagctggag
    21901 aaaaacaaaa aacatgatat cgcgatcgtc atcgaccgga tcattgtgaa agaagggatt
    21961 cgttctcgcc tatttgattc tttagaggcg gccctgcgat tagcagacgg ctatgctctg
    22021 gttgacgtga tcggtgaaga agaaatgttg tttagcgaac actatgcctg tccttattgc
    22081 ggatttactg ttggcgaact agaaccaaga ctgttctcat tcaatgcgcc ttttggagct
    22141 tgtccagact gtgatggttt aggtgtcaaa ttagaagtcg atcaagattt agtgattcca
    22201 gatagaacga agacacttag tcaaggtgct atcgttccat ggaatccaat cagctctcag
    22261 tattatcctc aaatgttagc gcaggcttgt gaaagtttcg gtatcgattt agatacacca
    22321 ttcgaagaat taccggaaga gcatcaggag atcatcttga atgggacaga tgatcttttc
    22381 catttccatt atgaaaatga ttttggtggc gttcgcgatg tagaaacgac tttcgaaggg
    22441 gtattgaaga atatcgagcg tcgttatcat gatacgaaca gtgatttcac gcgtgagcaa
    22501 atgcgtcttt atatgacaga attaacttgt cagacatgta aaggttatcg attgaatccc
    22561 caagctctat ctgttcaaat caatggaacg aatatcgggc aaacaaatga gttgtctatt
    22621 caaaaagcag tagatttctt ctcaaactta acgttatctg aacaagagaa agtaattgcc
    22681 aaaccgattt taaaagaagt aaatgacaga ctttcattct tggaaaatgt gggactagac
    22741 tatctaactt tgagtcgcgc ttccggaaca ttatctgggg gagaagcgca gcgaatcaga
    22801 ttggctacac aaattggatc gaatctttct ggagttttgt atattttaga tgaaccatcg
    22861 atcggattgc atcaacgcga caacgatcga ctgattggct cattaaagaa aatgcgtgat
    22921 cttggcaaca ccctcgttgt agtcgaacat gatgaagata cgatgtgggc agcagattat
    22981 ttgattgacg tcggacctgg ggccggagaa caaggcggac aaatcgtggc tgcaggcact
    23041 cctgaagaag tagctaatga tgaaaattct ttgacaggga aatatctttc agggaaaaaa
    23101 tcaatccctg taccaaaaga acgccgtaaa ggtaatggga aagcaatcaa gatcactggt
    23161 gcttcagaaa acaatctgaa aaatattagt gttgaatttc cattaggaga atttgtagca
    23221 gtcacaggtg tgtctggttc tggaaagagt acattggtca atagtatctt aaagaaatcg
    23281 ttagcgcaaa aattaaataa gaattctgct aagccaggta aattcaagac aatttccggc
    23341 tacgaaagta tcgaaaagat catcgatatc gatcaaagcc caatcggccg gacgccgaga
    23401 agtaatccag cgacttatac aagtgtattt gatgatatcc gtgggttatt tgctcaaacg
    23461 aacgaggcaa aaatgcgggg ttataagaaa gggcgtttta gtttcaacgt aaaaggcggt
    23521 cgttgtgaag cttgtcgcgg ggatggaatt attaagatcg aaatgcactt tttgcctgat
    23581 gtctatgttc cttgtgaagt atgtcatggt aaacgatata attctgaaac attagaagtg
    23641 cattacaaag gaaaaagcat tgctgatatt ttggaaatga cagtagagga tgctgtagaa
    23701 ttcttcaagc acattccaaa gattcatcgc aaactgcaaa cgattgttga tgttggctta
    23761 ggttatgtga cgatggggca accagcaacg acattgtccg gtggtgaggc acaacggatg
    23821 aaacttgcca gtgaattgca caaaatctct aatggaaaga atttctatat actagatgaa
    23881 ccaacgacag gacttcatag cgatgacatc gcccgcttgt tgcatgtatt acaaagatta
    23941 gtagatgctg gtaacacagt tttagtgatt gaacacaatc tagatgtaat caaaacagca
    24001 gattatatca ttgatttagg accagaaggt ggagaaggtg gaggaacgat ccttgcgact
    24061 ggaacaccag aagaaatcat taacgtaaaa gaaagttata caggtcacta tttgaaaaaa
    24121 ataatggtat aaagaggata gatagctgag atagttaaaa aaacataaaa aaatgaattt
    24181 ttgcttgttt tattaatatc agtgttctag aatcattaca tggtagttct ttctacactg
    24241 attggtatag ataaaaactt cctataagtt caatccgttc aaaaaagaat tgagcaatcg
    24301 gaggactttc ctttgattgc ttttttcttt atggtatgat attccttgtg tagttggaaa
    24361 agaaaaacaa gagattatga gtaagtgaga gataatgatg aacagtattg aaaatgaaga
    24421 atttatccct atattattag gaagcgacat gaacgtttat ggtatggcac gttcttttaa
    24481 tgaagcatac ggcaaaatct gccaagcata tgcttcggat cagttagccc ctacccgcta
    24541 cagtaaaatt gtcaatgtag aagttattcc aggatttgat aaagaccctg tatttatcga
    24601 gacgatgctt cgtttggcaa aagaaagata ttctgataag agtaaaaaat atcttttgat
    24661 tgcttgtggt gatggatatg cagaattgat ctcccaacat aaacaagagc tgtcagaata
    24721 ttttatctgt ccatatattg attattcttt atttgaaagg ctgatcaata aagtaagctt
    24781 ttatgaagtt tgtgaagaat atgatcttcc gtatcctaaa acattgatcg tcagagaaga
    24841 aatgttagta aatggacatt tggaacagga attgcctttt gaattcccag ttgctttgaa
    24901 acctgcaaac agtgtggagt atctttctgt ccaatttgaa ggaagaaaaa aagcttttat
    24961 tttagagact agagaagagt tcgatttaat tttaggccgg atatacgaag ccggttataa
    25021 aagtgaaatg attgtacaag attttatccc gggtgatgat agtaatatgc gtgtgctaaa
    25081 tgcgtatgta gatgaagatc atcaagttcg gatgatgtgc cttggtcatc cactattaga
    25141 agatcctaca ccagcatcga ttggtaatta cgttgtgatc atgccagatt ataacgaaaa
    25201 aatctatcaa accattaagg catttttgga aaaaatcgaa tatacaggct ttgccaattt
    25261 cgatatgaag tatgatccta gagatggaga atataaatta tttgaaatca atttgagaca
    25321 aggtcgtagc agtttctttg tgacattgaa cggcttgaat ctggctcgtt ttgtcacaga
    25381 agatcgagtg ttcaacaaac cctttgttga aacgacctat ggaacgaatc aatcagataa
    25441 agcaagatta tggatgggtg tgcccaaaaa aatcttttta gaatatgctc gggaaaatga
    25501 agacaaaaaa ctagctgagc aaatgatcaa agaaaatcgt tacggtacta ctgtatttta
    25561 tgaaaaagac cgatcaatca agcgctggtt gttgatgaaa tatatgttcc ataactatat
    25621 tccaagattc aaaaagtatt ttcatgtgaa agaaggctag ttcatggaga attttttcag
    25681 tattttaggc ggaatgggca cgatggcgac agaaagtttt gttcgcttga tcaaccaccg
    25741 aacgaaagct acaaaagatc aagaatattt gaattatgtc ttattcaatc atgcaacagt
    25801 tcctgatcgt acagcttata ttttagatcg atcagaagaa aatccaatgc cgtttctgct
    25861 ggatgatatt gagaaacaaa atttattgcg accaaacttc attgtgttga cttgtaacac
    25921 cgcacactac ttttttgaag agttacaagc ggcaacggat attcctatct tgcatatgcc
    25981 aagagaagca gcaaatgaac ttgtccgtca gcatacgaca gggagagtag cgattctagg
    26041 aacagaagga agtatgaaag ctggaatcta tgaacgcgaa gtcaaaaatc ttggtttcga
    26101 aacagtgatt cctgatactg cgcttcaaga aaaaatcaat tacctgatct atcatgagat
    26161 caaggaatcg gattatttga atcaagagct ctattacgaa atcttagagg aagcggtaga
    26221 gcgcctaaac tgtgaaaaag tcatcctagg ttgcacagaa ttatctttga tgcatgaatt
    26281 tgctgaagat aatcattacc cagtgatcga tgctcaatct attttagcgg atcgaacgat
    26341 cgaacgtgca ttagctgaaa gaagcgaggc attggataca gcatcggaaa agtaaaaaaa
    26401 ttggatttgg ggcaaatatc ctaaaagata tttggtccaa atctttttgt aaaagaaaaa
    26461 gaaaactggt aatgatacgc ccgggatgat ataattttat tatgcacaat gtgagagggg
    26521 ttcgtaaata tgacagataa tttgcaatta gtcatcataa caggtatgag tggtgcaggg
    26581 aaaacagtag ctatccaaag ttttgaagat atgggctatt tttgtatcga taatatgccg
    26641 cctcgattga ttccaaaatt ctgggaattg atcaaagaat caggtaaagt cacaaaaatg
    26701 gctttaggag tggatttgcg ttctcgttcc ttctttgaag aaatccaaaa catgctgatc
    26761 gaaatcgaaa atacgaactt catcgacact tctatcttat ttttagatgc ttcagacgaa
    26821 gaactagtgg ctcgctacaa agaaacaaga cgagcacatc caatggcgat ggacggtttg
    26881 atcactgaag ggatacgtaa agaacgggcg atactagacg acttgaaagc ccaagcttcc
    26941 gtgatcattg atacgacaac attgacacca cgacaattac gtgaaaaaat caatgagtca
    27001 ttcaaatcaa agggagacca aggatttcgg atcgaatttg tatcatttgg ttttaaatac
    27061 gggttgccga tcgattcgga tattgtgatg gatgtgcgtt ttttgcccaa ccctcattat
    27121 atcccggaac taagaccatt gaccggaaaa gatcagccag tctatgatta tgtgatgtcc
    27181 tttgatgaaa cgcaatcatt ctaccataaa tttttggatc ttctggaaac tgtattgcct
    27241 ggatacatta aagaaggaaa aagcagcttg acagttgcaa tcggctgtac aggcggtcaa
    27301 caccgttctg tggcattgac tgaacgtttg gcaaatgctt tagggaaaaa ctataaagtc
    27361 aatgtgacac atcgggacaa ggataaaagg aaagagacgg tgaaccggtc gtgaaaatga
    27421 aaacctaccg gataagaaaa ccaaagatcg tagtggtcgg cggtggcact ggtctgccag
    27481 ttatcctgaa aagtttacga aatcaaggag cagatatcac agcagtagtg actgttgcag
    27541 atgatggtgg aagcagcggt gcaatcagag aatcgatcgc tatggctcct cctggtgact
    27601 tgagaaatgt cttagtggcg ttatcggata tgccacaatt ctatgaagat attttccaat
    27661 accgtttcaa aaaggaagat cagtttttag ccaatcatac gatcggtaat ctgatcattg
    27721 ccgcagtttc cgagatgcgg ggaagcactt atgaggcgat tcaattatta gcaaaaatga
    27781 tgcatgtaga tggacatgtt tatccttctt cagaaactcc tttgaccttg catgctgttt
    27841 ttaaagacgg aacgactgca gtaggagaat ctaaaatcgc gatcaaccgt aaaaccattg
    27901 accgtgtgta tgtctgcaac acaaatgata aaagtgaagc caaagcggct cgaaaagtcg
    27961 tttcagcaat tatggacgcc gacatggtcg ttttgggacc cggaagttta ttcaccagta
    28021 tccttccaaa tttagtgata ccagaaatcg gcgaagcaat gctcaagaca actgctgaaa
    28081 ccgtctatat ctgtaatatc atgacccaaa aaggggaaac ggaacatttc acagatgccg
    28141 atcatatacg tgttttacac aagcatttga atcagccttt tatcgataca gtattggtca
    28201 atacggaaaa agtgcctgaa gattatatgg acccagagat ctatgatgag tatctagtac
    28261 aagtcgcaca cgacttcaac ggattgagaa atgaaggatg tcgagtgatt tccaccgact
    28321 ttttagaatt gaaagatggt ggtgtcttcc acgatggaga caaagtagta gaagaattgt
    28381 tccgtttagt tttcggttca aaatattaag caatttattg ttggagaaag gaggagaata
    28441 ggatgtcatt tgctgcagat gtgaagaaag aactaactgg tttggaagtt catcgagaac
    28501 atgcgaaagc ggaattagct gctttgctgc gaatgaacgg ctctttaggt attgtgaacc
    28561 agcagtttat tttgaacgtc caaacagaaa atgctgcaat tgccagacgt atctattctc
    28621 ttttgaaaga tcattatcag gtacgaagtg agctactcgt tcgtaaaaaa atgaaattaa
    28681 aaaagaacaa tgtctatatc gtccggttga agcaaggcac aaaagatgtg ttgatggatc
    28741 ttgatatcat ggatggtatg atgttcaatg gacacgtttc ggacgagatt atgggaaatt
    28801 cgcaaaaaat gcgttcttac ttacgtggtg cttttatggc ctcaggttca gtcaataatc
    28861 cggaaacgag tcgttatcat ttggaaatat tttctattta tgaacagcat aaccaagaca
    28921 tttgcgatat gttaaattat tacggtctac atgctcgaac gcttgaacgg cgcaatggct
    28981 atatttcgta tttaaaagga gcagaaaaaa ttgctgattt cttaacattg attggtgcaa
    29041 ccaactcaat gctccgattt gaagatgttc gaatcgtacg ggatatgaga aattcggtca
    29101 atcgtctagt caattgtgag acagcaaatc tgaacaagac gattgatgcg gcttctaaac
    29161 aaatcgaaaa catcgaattg atcgaagcaa aggtcggtct acatgccctt cctgaaaaac
    29221 ttcaggaaat cgcagaactt cggcttcaac atccagaggt cagcttgaaa gaattagggg
    29281 aaatgattcc ctcaggtgca atatcaaaat cgggaattaa tcaccgaatt cgcaaaataa
    29341 atgaatttgc ggaaaaactg cgtgaagaag cagtttaatc caaagaaaaa actgatacat
    29401 gaagcaggag atgcgaatgt atcagttttt tttaaaagct atacttgctt ttcttccgtc
    29461 aaactataat tccaacttta ctggagtaac ataatgttga aaggcttcta ttgtttttta
    29521 atacaatcgt ataaaaagcg gggagacaac tgaatgaaga ttttagtttt atacataaac
    29581 ttttgcttaa tatagaagtc ctgatataga taggatcaag tatttatcta taactggaga
    29641 ttaattaaaa actggaagga actgctcgat caaccttgag aactgttttt cttacttctg
    29701 gtcaagattc tcgtggttgg tggataagga tggttgataa gttcattgga ttagctagtc
    29761 gaaaacaacc aggtgtaatt aatgtagaag ttttaacaag gggatggagt gatttattca
    29821 gtgataatca taagttcata aatagtaatt gggatgtatg gttggtatac gttatacctg
    29881 aacttgaact atcaagattt ggtttagaat ttgagaatcg atgtttataa agggagggca
    29941 aaaaatgtgc ttttttacaa cttttactat cattatgatt gcagtacttt ttatttttct
    30001 agatatagca aagcgaaata cagcattttt attatatcgg gttttacttc gagcaggtct
    30061 cataacattt atatcgatcg ttggattttt tctattcaca gttattgtat ttatttggag
    30121 aactacagca ccaccattgc cagagattac atatggagaa tttccgttta gtcttgaata
    30181 tgaaatagat gaggaaagaa ttttgattga agatacggtg attgcagaat ttataggaag
    30241 ttttagaggg aatgtgacaa ctcaacctag acgaagttgg agtataaaac ttttaaataa
    30301 tagtggagag ttgaaagcat ttcattatga attcttaata atagaaagtg aagatgtaac
    30361 aatcacttta agtagtggct ctgctggata ttttatgaat gatggtggaa gcaagccaca
    30421 gctcacagtc cgtgatcgta ttgcaggttt tatgcatttt tctcactatg acttagaaga
    30481 agctcgtaaa atacttgcag aatatgggat cacattaatc aattgggaat atgcgccacc
    30541 gataagaaat tttttcaatg attattatta gtcttataaa aaacagaatg taaaatttat
    30601 gtgcgcgagt atttagtttt ccattttttg tttgatagat atatagcatt gttgaagcat
    30661 gggatagtgg tgccaatttt atcaatgagg ttggtcaggc agttaacata attggtgatg
    30721 ctataaatcc atttaattgg aattggagga attaggtgtg gaaacagtga gattatggat
    30781 attcatgaaa aattttcgtt cggctttgag atatgttatt ctggaatcaa aatcaggtta
    30841 ttatctgatt gacacagatc actatacttt ttggggaggc tacctttttc cgatttttaa
    30901 ttggataatc ccccataagg ttatgaaaat taacttgcct gcagaagaaa taaatagatt
    30961 aatactcaac aaagatttac aaaggaaaag agagaaagaa cattctaatg ttgcttggat
    31021 aggtccagca tttgcagtag tgacttcttc aattgtcggt cctatgctag agagtattta
    31081 tagtgatttt tctattggaa tacgttattt atttgttact ttaagtatag ctgttctttt
    31141 gtgcataaag ggttatgtta gcaagaagaa taaagatatt ttaacactaa tcggtgtaaa
    31201 caatttatct agtactaaaa ttatactgtt tcctgaatct ataaaagaag gatcaaggtt
    31261 gttgataatt tttataatgc ttatactgtt ttctgtttta tttggggtga tgtttata
//
LOCUS       DAFBVQ010000027        30088 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.027, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000027 DAFBVQ010000000
VERSION     DAFBVQ010000027.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 30088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 30088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..30088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.027"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(41..1525)
                     /gene="guaB"
                     /locus_tag="LLC22_001447"
     CDS             complement(41..1525)
                     /gene="guaB"
                     /locus_tag="LLC22_001447"
                     /EC_number="1.1.1.205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875762.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IMP dehydrogenase"
                     /protein_id="HBK5434730.1"
                     /translation="MSNWETKFTKKGFTFDDVLLIPAESHVLPNEVDMSVQLAKNIKL
                     NIPIISASMDTVTDSKMAIAMARQGGLGVIHKNMTISQQADEVRKVKRSESGVIIDPF
                     FLTPQHLVADAEELMSKYRISGVPIVETLENRKLVGIITNRDMRFVTDYHMPIADVMT
                     KDNLVTAPVGTSLKDAEKILQKHKIEKLPIVDNEGRLSGLITIKDIEKVIEFPNAAKD
                     EHGRLLVAAAVGVTSDTFERANALLEAGADAIIIDTAHGHSAGVIRKIQEIRSTFADA
                     TLIAGNVATAEATKALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQLTAIYDAASVAR
                     QYGKAIIADGGIKYSGDIVKALAAGGHAVMLGSMLAGTDESPGEFEIFQGRRFKTYRG
                     MGSLGAMEKGSKDRYFQGSVNEANKLVPEGIEGRVAYKGSVADIIFQMIGGLRSGMGY
                     VGAANLQQLRDEAQFIQMSGSGLKESHPHDVQITKEAPNYSVES"
     gene            complement(2030..2725)
                     /locus_tag="LLC22_001448"
     CDS             complement(2030..2725)
                     /locus_tag="LLC22_001448"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1129 domain-containing protein"
                     /protein_id="HBK5434731.1"
                     /translation="MEPEQLRAIVKENNSLETKLTKRNQQYIFDLKKSLEAANLSEEE
                     KVKALHDILPTLVAEQKGGRTARQLFGTVSERTEAIINKPAEVKNSSTPLLMWLDNTL
                     LLLGLLSIMIAITGLFSRGTTPAYGFSTLVLGSAIGGWVFYMMYKYIYQYEYPGADRS
                     KKPGMGKTLLILGGTTLLWVVLFSATTLLPPVINPVLDPVVVIIIGATALAIRYYLKK
                     KYGIIGSLSVPRR"
     gene            complement(2815..3915)
                     /gene="ychF"
                     /locus_tag="LLC22_001449"
     CDS             complement(2815..3915)
                     /gene="ychF"
                     /locus_tag="LLC22_001449"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="redox-regulated ATPase YchF"
                     /protein_id="HBK5434732.1"
                     /translation="MALTAGIVGLPNVGKSTLFNAITKAGAEAANYPFATIDPNVGMV
                     EVPDWRLQRLTELVHPKKTVPTTFEFTDIAGIVKGASKGEGLGNQFLSHIRQVDAICH
                     VVRCFDDDNITHVEGRVDPLEDIDTINLELVLADLESINKRYTRVAKVAKTKDKDAVA
                     ELAVLDKIKPVLEEGKSARTIEFTEEEQKIVKSLFLLTTKPILYVANVSEDDVADADA
                     NHYVQEVRNFAAEENAEVIVVSARAEEEIAELDEEDKAEFLEALGIEESGLDQLIRAA
                     YDLLGLATYFTAGEQEVRAWTFKKGIKAPQAAGIIHSDFERGFIRAETVSFEDLDHYG
                     NMHAAKEAGRVRLEGKDYVVQDGDVMLFRFNV"
     gene            complement(3924..4115)
                     /locus_tag="LLC22_001450"
     CDS             complement(3924..4115)
                     /locus_tag="LLC22_001450"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF951 domain-containing protein"
                     /protein_id="HBK5434733.1"
                     /translation="MYDLHDIVEMKKPHACQTNRWEVIRMGADIKIRCMNCGHIVMMT
                     RRDFEKKLKKVIEKNAEKE"
     gene            complement(4136..5026)
                     /locus_tag="LLC22_001451"
     CDS             complement(4136..5026)
                     /locus_tag="LLC22_001451"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParB/RepB/Spo0J family partition protein"
                     /protein_id="HBK5434734.1"
                     /translation="MKKSKGLGRGIDALFQDLENLETVDVKDDTVVQLPLNELRPNPY
                     QPRKTFEEVSLQELANSIEQSGVFQPIIVRRSAVKGYEIIAGERRFRASKLAEKETIP
                     AIVRDFDEEAMMQVAVLENLQREDLNPLEEAEAYEMLMKNLKLTQAEVASRLGKSRPY
                     IANYLRLLSLPDLVKEMVQDQRLSMGQARTLLGLKNKTLILKLANRAVTENLTVRQLE
                     QLVSELNQNDGKEKKKIPRLAKEKPYYIRESEDRLMDKFGTSVAIQEKNGKGKIEIEY
                     LSQKDLTRILDILNIQFDEE"
     gene            complement(5013..5780)
                     /locus_tag="LLC22_001452"
     CDS             complement(5013..5780)
                     /locus_tag="LLC22_001452"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK5434735.1"
                     /translation="MAQIISVANQKGGVGKTTTTVNLGACLASLGKKVLLVDMDAQGN
                     ATSGVGIRKPDVTRDIYDVLVNELPIDEATLITEHENLSIVPATLQLAGAEIELTSMM
                     ARESRLKGSLAEVSSQYDYILIDCPPSLGHLTINSFTASDSILIPVQCEYYALEGLSQ
                     LLNTVRLVQKHFNPELEIEGVLLTMYDARTNLGNEVVEEVRKYFREKVYETIIPRNIR
                     LSEAPSHGKPIIDYDPRSRGAEVYQALAKEVVSREEK"
     gene            complement(5792..6505)
                     /gene="rsmG"
                     /locus_tag="LLC22_001453"
     CDS             complement(5792..6505)
                     /gene="rsmG"
                     /locus_tag="LLC22_001453"
                     /EC_number="2.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="16S rRNA (guanine(527)-N(7))-methyltransferase
                     RsmG"
                     /protein_id="HBK5434736.1"
                     /translation="MIPEEFRQSLAEKGIELTDHQMNQFAIYYRTLVEWNEKMNLTAI
                     TDEKDVYLKHFYDSLTLAFEVDFTQPLSLCDVGSGAGFPSIPLKIAFPELQITIVDSL
                     NKRITFLSELTRLLGIDASLYHDRAETFGQNPHFRASFDLVTARAVARLNVLAELCLP
                     LAKQEGYFYALKAAKSEEELTEAKQAIALLGGKFLKEEAVTLPNVSDQRHIIVIQKKK
                     PTPKKYPRKPGLPNKQPIK"
     gene            complement(6737..8638)
                     /gene="mnmG"
                     /locus_tag="LLC22_001454"
     CDS             complement(6737..8638)
                     /gene="mnmG"
                     /locus_tag="LLC22_001454"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis enzyme MnmG"
                     /protein_id="HBK5434737.1"
                     /translation="MEHYEADAYDVIVVGAGHAGSEAALAAARMGSKTLLLTINLDMV
                     AFMPCNPSVGGPAKGVVVREIDALGGEMGKNIDKTYIQMRMLNTGKGPAVRALRAQAD
                     KHAYSTEMKHTIEKEPNLTLRQGIVEELIVEDGVCHGVVTSTGASYRAKAVVITAGTA
                     LRGEIIIGELKYSSGPNNSQPSIGLANHLKELGFAIERFKTGTPPRVKSSTIDYSVTE
                     EQPGDKEPNHFSFSTPDSAYKLDQESCWLTYTGETTHQIIRDNLHRAPMFTGIVEGVG
                     ARYCPSIEDKIVRFADKPRHQLFLEPEGLNTEEVYVQGLSTSLPEDVQVNMLHSIAGL
                     EKVEMMRTGYAIEYDVVEPHQLRPTLETKVVENLYTAGQTNGTSGYEEAAGQGLIAGI
                     NAALKVQGKEPLVIKRSDGYIGVMIDDLVTKGTNEPYRLLTSRAEYRLLLRHDNADLR
                     LTEMGHRVGLVKEDQYKNYLKKKEAVEQEIKRLMNVRIKPTEEVQDFLATINAAPLKD
                     GVLASDFLRRPEITYAELLRFIPENEELTRKEIEQVEIQIKYEGYIKKAMEKVEKLKR
                     MEAKKIPENIDYAAINGLATEAKQKLQKIQPETIAQASRISGVNPADLSILMVYIEQG
                     KIAKVSEPA"
     gene            complement(8655..10052)
                     /gene="mnmE"
                     /locus_tag="LLC22_001455"
     CDS             complement(8655..10052)
                     /gene="mnmE"
                     /locus_tag="LLC22_001455"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA uridine-5-carboxymethylaminomethyl(34)
                     synthesis GTPase MnmE"
                     /protein_id="HBK5434738.1"
                     /translation="MAEITLEFDTIAAISTPPGEGAISIVRLSGDQAVQLADKVYQSG
                     NKRLSEVPSHTIHYGHIVDPKSNQLVDEVMVSVMRAPKTFTREDVVEINCHGGIVVVN
                     QILQLLLREGARLAEPGEFTKRAFLNGRVDLSQAEAVMDLIRAKTDKAMGLALNQLDG
                     NLSALIRSLRQEILETLAQVEVNIDYPEYDDVEELTTKLLLEKAQMIQQRIQALLATS
                     KQGKVLREGLSTAIIGRPNVGKSSLLNHLLREEKAIVTDIAGTTRDVIEEYVNVRGVP
                     LKLIDTAGIRETEDVVERIGVERSRKALAEADLILLVLNQSEPLTAEDEQLLEATSGL
                     KRIILLNKTDLPAQLEQEKLKKLIENEPVFSISVAKNDGLDRLESAISDLFFSGETGE
                     RDATYVSNTRHIALLEKASLSLEEVIAGIDSGMPVDLVQIDMTRCWDYLGEVVGDSVQ
                     DELITQLFSQFCLGK"
     gene            10351..10734
                     /locus_tag="LLC22_001456"
     CDS             10351..10734
                     /locus_tag="LLC22_001456"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434739.1"
                     /translation="MVALSKLYTFERRKYVSPFRSAALEEESDPRINDVVLSTGNINQ
                     KYIVRDIVFVVECLEADLFDPSFPKDDLFLTTKRKLKTKVLEYGANAVINCHFEYQQK
                     KRDGKYFLELFAYGTVIQFIQTTIG"
     gene            complement(10902..11660)
                     /locus_tag="LLC22_001457"
     CDS             complement(10902..11660)
                     /locus_tag="LLC22_001457"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Jag N-terminal domain-containing protein"
                     /protein_id="HBK5434740.1"
                     /translation="MPIYEAATIDEAVQLGLADLGLAKDQVEIEILEEGKKGFLGMGR
                     KNARLSIQPSISEKVSETVEQTVEEILEEEPTAEIEVVNETILEEKTEEVSELGDEAA
                     LTELAVYLTEISKQLDAPALVKMERESNNMVVFHLETQKQGILIGKHGKTLNALQYLA
                     QVFIHRLARNKLSVVVNVGNYREKRQEIIQRLADRTAEKVKRTGQPVFLEPMPAFERK
                     QIHAALSKDEHVKTHSEGEEPYRYLVVEPAKKYY"
     gene            complement(11678..12496)
                     /locus_tag="LLC22_001458"
     CDS             complement(11678..12496)
                     /locus_tag="LLC22_001458"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332030.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBK5434741.1"
                     /translation="MKKYKRLLLMAGIVSLVIVLSGCGTGEVSAQSTGIWDRYIVYYF
                     AEAIKALSFGNAGIGIILFTLIIRVILLPLMHFQTKSMRKTQELQPKLKALQQQYSSR
                     DPETQSKLREEQQRLYAENGVNPYAGCLPLLVQMPILMALWQSISRVPELKQGHFLWL
                     NLGNADPTFILPILAAIFTFASTYLSSMSQIESNASMKIMNFVMPVMILVMGVNLASG
                     LSLYWVVSNAFQVVQTLLINNPFKIRKEREEEARRIRERERALKKAMNPKKKRK"
     gene            complement(12493..12849)
                     /gene="rnpA"
                     /locus_tag="LLC22_001459"
     CDS             complement(12493..12849)
                     /gene="rnpA"
                     /locus_tag="LLC22_001459"
                     /EC_number="3.1.26.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720505.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease P protein component"
                     /protein_id="HBK5434742.1"
                     /translation="MRKAYRVKKEREFQAVFHTGDSFANRKFVVYRLEKPGQPHFRVG
                     LSVGKKVGNAVNRNEVKRKIRAAVYSIKEEIDPELDFIVIARPSVKGLTYDEVRSNLV
                     HVLKLAKIIDREEKSK"
     gene            complement(12967..13101)
                     /gene="rpmH"
                     /locus_tag="LLC22_001460"
     CDS             complement(12967..13101)
                     /gene="rpmH"
                     /locus_tag="LLC22_001460"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003397591.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L34"
                     /protein_id="HBK5434743.1"
                     /translation="MKRTYQPNKRKRQKVHGFRKRMSTKNGRRVLASRRRKGRKVLSA
                     "
     gene            13624..14958
                     /gene="dnaA"
                     /locus_tag="LLC22_001461"
     CDS             13624..14958
                     /gene="dnaA"
                     /locus_tag="LLC22_001461"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720504.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosomal replication initiator protein DnaA"
                     /protein_id="HBK5434744.1"
                     /translation="MVSLDALWNELKATYQKDLSPASYNTWIETANPRTLDQNQLVVE
                     VPSKIHKEYWEKNLATKIVEVGYMLSGNEIIPRFITGEEAEQEEVIEEKNPKVVAPSP
                     LKKAMLNPKYTFDTFVIGKGNQMAHAAALVVAEDPGSIYNPLFFYGGVGLGKTHLMHA
                     IGHQMLQSQPNAKVKYVSSETFANDFINSIQNKTAEEFRQEYRNVDLLLVDDIQFFAE
                     KEATQEEFFHTFNALYNEGKQIVLTSDRLPNEIPKLQERLVSRFAWGLSVDITPPDLE
                     TRTAILRKKAAAERLEIPDDTLSYIAGQIDSNIRELEGALVRVQAFAAMNSEDISTSL
                     AADALKTLKSGKGHPQLSILQIQEEVAKYYHIQLKDLKGKKRVKSIVVPRQIAMYLAR
                     ELTDNSLPKIGAEFGGKDHTTVIHAHEKIQQLMDSSVSMQNEVSEIKNFLLN"
     gene            15156..16286
                     /gene="dnaN"
                     /locus_tag="LLC22_001462"
     CDS             15156..16286
                     /gene="dnaN"
                     /locus_tag="LLC22_001462"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit beta"
                     /protein_id="HBK5434745.1"
                     /translation="MKVTLNRASFMQELQTVQRAISSKTTIPILTGVKITLTQEGLTL
                     TGSNADISIETFLSVENEKANMQIESTGSIVLQARFFSEIIRRLPEETFTLEVLENKQ
                     VAITSGKANFIVNGLDADNYPHLPVVESHNQMKLPVHVLTKLINETVFAVSQHESRPI
                     LTGVHFILSDNSLLAVATDSHRLSQRVIPVEQAADHFDIVIPGKSLIELSRSLTNEEE
                     IVEISIMENQVLFKTETMYFYSRLLEGNYPDTNRLIPSSFNTEVEFSVPSFLAAIERA
                     SLLSHEGRNNIVRLSIRPDAVVLYGNSPEIGKVEESLSYTASSGDPLDISFNPDYMKA
                     ALRAFGDMSIKVKFISAIRPFTLEPTEDGVQFIQLITPVRTN"
     gene            16515..16757
                     /gene="yaaA"
                     /locus_tag="LLC22_001463"
     CDS             16515..16757
                     /gene="yaaA"
                     /locus_tag="LLC22_001463"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S4 domain-containing protein YaaA"
                     /protein_id="HBK5434746.1"
                     /translation="MKQQVILNTEFMTLGQMLKEVTVIGSGGQAKWYLAENTVLVDGE
                     PENRRGRKLYPGMMVEVPEVGTFFMVKKGNDDNEAE"
     gene            16744..17868
                     /gene="recF"
                     /locus_tag="LLC22_001464"
     CDS             16744..17868
                     /gene="recF"
                     /locus_tag="LLC22_001464"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309899.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA replication/repair protein RecF"
                     /protein_id="HBK5434747.1"
                     /translation="MRLNKLYLKNYRNYEELNIEFSKNLVIFLGENAQGKTNLLESIY
                     VLAMTRSHRTSSEQELIGWTDDQAMIQGEITKGSSTLPLEILLSKKGRKTKINHIEQK
                     KLSTYVGQMNVILFAPEDLSLVKGSPQTRRKFLDMELGQINPIYLYDLVQYQAILKQR
                     NQYLKQLNEKKQTDLLYLDILSEQLAAFGSKVLKARAQFVKRLEFWANSLHQQITHQK
                     EQLEIEYLTAVDSLETHTQEQIQEQFLALLNQNKKKDLFRGTTTVGPHRDDLSFFINQ
                     KNVQTYGSQGQQRTTALSVKLAEIDLIKEETGEYPILLLDDVMSELDDNRQLHLLETI
                     EGKVQTFLTTTTLDHVKNKMTVEPEIFYVQQGKLKGEETE"
     gene            17865..19811
                     /gene="gyrB"
                     /locus_tag="LLC22_001465"
     CDS             17865..19811
                     /gene="gyrB"
                     /locus_tag="LLC22_001465"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003129249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase (ATP-hydrolyzing) subunit B"
                     /protein_id="HBK5434748.1"
                     /translation="MTEERSLVERAKEYDASQIQVLEGLEAVRKRPGMYIGSTSSEGL
                     HHLVWEIVDNSIDEVLAGFATKIHVIIEKDNSITVIDDGRGIPVDIQAKTGRPAVETV
                     FTVLHAGGKFGGGGYKVSGGLHGVGSSVVNALSTQLDVKVYKEGNVYYQEYRRGAVVD
                     DLKIIEQTDRHGTTVHFTPDPEIFTETTEFDFSKLATRIRELAFLNRGMRISIEDKRE
                     EEPVINEYHYDGGIKSYVEYLNANKTVIFPEPVYLEGEQQDIAVEVSMQYTDGYHSNI
                     MSFANNIHTYEGGTHESGFKTALTRVINDYARKQKLMKENDDNLTGEDVREGLTAVIS
                     IKHPDPQFEGQTKTKLGNSEVRTVTDRLFSEHFMKFLLENPSVGRQIVEKGLLASRAR
                     LAAKRAREVTRRKGALEISNLPGKLADCSSNDPEKCELFIVEGDSAGGSAKQGRNREF
                     QAILPIRGKILNVEKASMDKILANEEIRSLFTAMGTGFGEDFDVSKARYHKLVIMTDA
                     DVDGAHIRTLLLTLFYRYMRPIVEAGYVYIAQPPLYGVKQGKNITYVQPGKNAEEELK
                     QVVASLPASPKPSVQRYKGLGEMDDHQLWETTMDPSNRMMARVSVDDAIAADQIFEML
                     MGDRVEPRRAFIEENAHYVKNLDI"
     gene            19831..22302
                     /gene="gyrA"
                     /locus_tag="LLC22_001466"
     CDS             19831..22302
                     /gene="gyrA"
                     /locus_tag="LLC22_001466"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631904.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA gyrase subunit A"
                     /protein_id="HBK5434749.1"
                     /translation="MSEEIRENIHDVNLTSEMKDSFIDYAMSVIVARALPDVRDGLKP
                     VHRRILYGMNELGVTPDKAHKKSARIVGDVMGKYHPHGDYAIYESMVRMAQPFSYRYM
                     LVDGHGNFGSVDGDGAAAMRYTEARMSKIATEMLRDINKNTVDFQSNYDDTEKEPVVL
                     PARFPNLLVNGTTGIAVGMATNIPPHNLSEVVAAIDLLMDNPDVTTNELMEVLPGPDF
                     PTGGLVMGKSGIRRAYETGKGSITVRAKVEITEMPNGKERIIVTELPYMVNKAKLIER
                     ISELHRDKRIEGITDLRDESSREGMRIVIDIRRDASASVILNNLYKLTSLQNSFGFNM
                     LAIEKGVPKVLSLKQILENYIEHQREVITRRTVFEKEKAEARAHILEGLRIALDHIDE
                     IIAIIRGSKSDDEAKATMIERFDLSDRQSQAILDMRLRRLTGLEREKIENEYQELLKL
                     IEDLTDILARPERVTEIIKNELADLNQRFGDKRRTELLVGEVLSLEDEDLIEEEEIVI
                     TLTNNGYIKRLANNEFRAQRRGGRGVQGMGIHNDDFVKNLVSCSTHDTLLFFTNNGKV
                     YRAKGYEIPEYGRTAKGIPIINLLGIDSSESIQAIIAVTGEAEEGHYLFFTTRQGTVK
                     RTSVTAFANIRSNGLIAIGLKEDDELVNVLLTDGQSNIIIGTHNGYSVTFKEEAVRDM
                     GRTASGVRGIRLREEDYVVGAALMKEDQEVLVITEKGYGKRTKVSEYPVKGRGGKGIK
                     TANITEKNGPLAGLTTVSGDEDIMLITDKGVIIRFNVSTVSQTGRSTLGVRLMKMEAD
                     TKVVTMAAVEPEAAEQTVEEQGSEE"
     gene            22538..22837
                     /locus_tag="LLC22_001467"
     CDS             22538..22837
                     /locus_tag="LLC22_001467"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005226363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S6"
                     /protein_id="HBK5434750.1"
                     /translation="MENTKYEIMYIIRPNIDEEAKTALIERFDAILKDNGAEVIESKD
                     WEKRRFAYEMNGYREGIYHIVKVSSPSSANAVNEFDRLAKINDDIIRHMIVKEEA"
     gene            22887..23399
                     /gene="ssb"
                     /locus_tag="LLC22_001468"
     CDS             22887..23399
                     /gene="ssb"
                     /locus_tag="LLC22_001468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5434751.1"
                     /translation="MINNVVLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQSGNR
                     EADFINCVIWRKSAETLANYARKGTLLGVTGRIQTRSYDNQQGQRVYVTEVVADNFQL
                     LESRSASENRQQSGGFQSSGQSAGGFGGNNNSNQTSQSSNGMPDFDRDTSDPFGSSST
                     IDISDDDLPF"
     gene            23425..23661
                     /locus_tag="LLC22_001469"
     CDS             23425..23661
                     /locus_tag="LLC22_001469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S18"
                     /protein_id="HBK5434752.1"
                     /translation="MAQQRRGGRKRRKVDYIAANHIEYIDYKDIELLKRFISERGKIL
                     PRRVTGTGAKNQRKITVAIKRARIMGLLPFVSED"
     gene            23804..25777
                     /locus_tag="LLC22_001470"
     CDS             23804..25777
                     /locus_tag="LLC22_001470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DHH family phosphoesterase"
                     /protein_id="HBK5434753.1"
                     /translation="MENKNNHLSPKPLFLILFILIEVLVVLILPFRFVSASVILLMNL
                     WGVRYWLKMKRWLILNKREKIQQASTVAETNLAYVSEVMPVGVIAYQPSSQKIEWLNP
                     LALKIKDQSGLTEEELLDTFFTAKEKKKNQVYLADKTFQFDMDTVKGVVYFNDITQNQ
                     LLKLHQTNSQPVIGILSIDNYADAIDKLDDKEISYLNSFVTTLVSDWMNEYHVFFKRI
                     NAERFFFVAQMIDLKKMMDKKFDLLDRFRAEAEKQSSPITLSMGIAYGSRTLDEIGGE
                     AQNNLDVALVRGGDQVVVKEVKEGAKPVYYGGKSAKNVKRTRVRSRAMSTALRRIFDE
                     TGDVFIMGHKFPDMDALGSAFGVSCLARFNQKKAYIVINENEIIPDVERCLEEIHKHP
                     ELEMQLISPERAIELKKEEDLLVMVDYHKPSLSISQGLYEQFDKIVIIDHHRRGEEFP
                     SKPLLTYIESSASSASELVSELIQYQSSKTNRLDRFEATLLLAGMVVDTNSFNVRTTA
                     RTFDVASYLRSCGADASLVQYLLSSDLATYLEISNLIAGSDYVTSDIVVAAGTDEKEY
                     NSVIAAKTADTLLSMININAAFVITKRTDGLIGISARSTGTINVQIIMESLGGGGHFT
                     NAATQLENTTVEETKQKLFAAIKENMNQIYDKE"
     gene            25783..26235
                     /gene="rplI"
                     /locus_tag="LLC22_001471"
     CDS             25783..26235
                     /gene="rplI"
                     /locus_tag="LLC22_001471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371936.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L9"
                     /protein_id="HBK5434754.1"
                     /translation="MKVIFLQDVKGKGKKGDIKEVPAGYAQNYLIKNNLAKEATKSSI
                     SQLAGQKKAQEKHEAEILEEAKKLKEFLEKEDTVVELKAKAGEDSRLFGSIPSKQIAE
                     GLNKQYKIKLDKRKIELENPIRSLGYTNVPVKLHHEVTATIKVHVVQE"
     gene            26509..27876
                     /gene="dnaB"
                     /locus_tag="LLC22_001472"
     CDS             26509..27876
                     /gene="dnaB"
                     /locus_tag="LLC22_001472"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replicative DNA helicase"
                     /protein_id="HBK5434755.1"
                     /translation="MNEVWQDRIPPQNIEAEQAVLGSVFLDAETIIDAMEYIEPKDFY
                     RRGHQIIFETMIELNDRNEAIDVVTVKDRLEQANLLEDAGGLSYLSDLALAVPTAANI
                     VYYAKIVEEKSLLRTLIQTATGIVTKGFEQGEEVQTILDDAERSILEVSEKRNRSGFL
                     SIAEVLNSTIENIDRLAQNNEEITGLPTGYQGLDKMTAGFQPEELIILAARPAVGKTA
                     FALNIAQNVGTKTDRSVAIFSLEMGAESLVNRMLCAEGSIEASHLRTGQLSEEEWSNL
                     IVAMGSLSRANIFIDDTPGIKISEIRAKCRKLAQEKGNLGLILIDYLQLIEGNGKENR
                     QQEVSDISRQLKKLAKELKVPVIALSQLSRGVEQRQDKRPVLSDIRESGSIEQDADIV
                     AFLYRDDYYEREGGDDDDGNEPKNDNVIEVIIEKNRSGARGTVELLFIKEYNKFSSLS
                     PREEF"
     gene            28656..29948
                     /locus_tag="LLC22_001473"
     CDS             28656..29948
                     /locus_tag="LLC22_001473"
                     /EC_number="6.3.4.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359213.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="adenylosuccinate synthase"
                     /protein_id="HBK5434756.1"
                     /translation="MSSVVVVGTQWGDEGKGKITDFLSENAEVIARYQGGDNAGHTIK
                     FNGVTYKLHLIPSGIFYKDKISVIGNGVVVNPKSLVKELAYLHEKGVETSNLRISDRA
                     HVILPYHIKLDQLQEDAKGENKIGTTIKGIGPAYMDKAARVGIRIADLLDKEIFEERL
                     RLNLDDKNRQFVKMFDSEPLDFDDIFEEYYEYGQQIKQYVTDTSVILNDALDAGKRVL
                     FEGAQGVMLDIDQGTYPFVTSSNPVAGGVTIGSGVGPSKINKVVGVCKAYTSRVGDGP
                     FPTELFDETGEQIREVGREYGTTTGRPRRVGWFDSVVMRHSKRVSGITNLSLNSIDVL
                     SGLETVKICTAYELDGELIYHYPASLKELNRCKPIYEELPGWSEDITGCKTLAELPEN
                     ARNYVRRISELVGVRISTFSVGPDRTQTNILESVWAQI"
BASE COUNT         9082 a         5949 c         5935 g         9122 t
ORIGIN      
        1 aaaagtgttc tttacttttg tcccacgctc tttaatgttt ttaagattca actgaatagt
       61 ttggtgcttc ttttgtgatt tgtacatcat gagggtgtga ttcttttaat ccactgccgc
      121 tcatttggat aaattgcgct tcatcacgta attgctgtag attggctgcc ccaacataac
      181 ccattcctga acgcaaaccg ccgatcattt ggaaaataat atctgcaaca cttcctttat
      241 aagcaacccg accttcgatt ccttctggta ctaatttatt tgcttcattg acactacctt
      301 ggaagtaacg gtcttttgaa cctttttcca tcgcgcctaa tgagcccata cctcggtatg
      361 ttttgaatcg acgtccttgg aagatttcga attcacctgg tgattcatct gtccctgcca
      421 acatacttcc tagcatcact gcatgtccgc cggcagctaa tgctttgacg atgtcaccag
      481 aatatttgat ccctccgtct gcaataatcg ctttgccata ttgacgagca actgatgctg
      541 catcataaat agctgtgagc tgaggtacac ctacaccggc taccacacgt gtcgtacaaa
      601 tcgatcctgg tccgatacca acttttacga catctacacc tgcatcatat aaagcttttg
      661 tcgcttcagc cgtcgcaacg tttcctgcaa tcaatgttgc atctgcaaaa gttgaacgga
      721 tttcttgaat ttttcggatc acacctgcac tatgtccatg agctgtatcg atgatgattg
      781 catctgcccc tgcttctaat aaagcattcg cacgctcaaa tgtatcgctt gttacaccaa
      841 cggctgctgc tacaagcaat cgaccatgtt catcttttgc tgcatttgga aattcgatca
      901 ctttctcgat gtctttgatc gtgatcaatc cgcttaaacg accttcgtta tctacgattg
      961 gtaatttttc gattttatgt ttttgcaaaa tcttttctgc atcttttaga gaggtaccta
     1021 ctggggcagt cactaagttg tcttttgtca tcacatcagc aatcggcatg tgataatctg
     1081 ttacaaaacg catgtcgcgg tttgtaatta tccctaccaa ttttctgttt tcaagtgttt
     1141 caacgattgg cacaccactg atacgatatt tgctcatcaa ttcttctgcg tctgctacaa
     1201 gatgctgtgg cgttaagaag aacggatcaa tgattacgcc actttcagaa cgtttgactt
     1261 ttcttacttc atccgcttgc tggctgatcg tcatgttttt atggatcaca cctagtccgc
     1321 cttgtcttgc catagcaatg gccatcttgc tgtcggtaac agtatccata cttgcactga
     1381 tgattggaat attcaactta atatttttag ctaattgtac gctcatatcc acttcgtttg
     1441 gtaacacgtg actttctgct ggtatcaata agacatcatc aaaagtaaat ccttttttcg
     1501 tgaactttgt ttcccagttg gacattttta gtaccactcc tctaatttag tttatctatt
     1561 aaaataattg attttttcat ttaagtcaat gatctacttg gaatcaagtt agctttctca
     1621 tagaatacca atataaagcg tttacatctg tgtatattaa aagagattgt aaaaaagctg
     1681 tcctgcatca agtaataaga acagccaatc aaaaacagct tctcatgttt ttgaattggt
     1741 tgggtttatt accgcagatg caaacttttg aacaccgttt agtggagagg ctgtgaaaaa
     1801 gctgcttagt ttcgagtagt aagaaaaatt ttgtgaaaat ggctttccac atttttgcat
     1861 aaattggact taataccgag aaactggctt ttgaacaccg tttatcgtaa aaagggactg
     1921 tgacaagact tttgtcacag tcccttacta ttatttaact atggataaac aaaatgaggt
     1981 tctttactac ccctagatat ctagcaaaat agctgatctt tttgctagtt tatcttcttg
     2041 ggacggataa acttccaata atcccgtatt ttttcttcaa gtagtaacgg attgctaaag
     2101 cagttgcccc gataatgata actactactg gatctaatac tggattgata actggtggca
     2161 atagtgttgt cgcagaaaac agtacgaccc aaagaagtgt cgttccacct aggataagca
     2221 atgtcttacc cattcctggt ttcttgcttc gatctgctcc gggatattca tattgataga
     2281 tgtatttgta catcatataa aagacccagc caccgattgc agaacctaga acgagtgtag
     2341 aaaagccata agctggcgtt gttccacgtg aaaacaatcc ggtaatcgca atcatgatac
     2401 ttaatagacc aagcaacagc aacgtattat ctaaccacat caataaaggg gtggatgaat
     2461 tttttacttc tgctggctta ttgatgattg cttccgttct ttcagagact gtcccaaaca
     2521 attgacgggc tgttcttccg cctttttgtt ctgcaactaa agtaggcaga atgtcatgaa
     2581 gggcttttac tttttcttct tcagacaaat tcgctgcttc taaagatttt ttcaaatcaa
     2641 aaatgtactg ttgatttctt ttggttaatt ttgtttctaa actattgttt tcttttacga
     2701 ttgctcgtaa ttgttctggt tccattatct aatagtcctc cttagccgtt ccttttctca
     2761 acggtcgtca caaaagacat tctaccatat tctacagcta gtttgatagc ccttttacac
     2821 attaaagcgg aataacatta cgtcgccgtc ttgtacgaca taatcttttc cttctaatcg
     2881 aacacgtcca gcttcttttg ctgcatgcat gtttccgtaa tgatccaagt cttcaaaaga
     2941 gacagtttct gcacggataa atccgcgttc gaaatctgaa tggatgattc ctgctgcttg
     3001 tggtgctttg attccttttt tgaatgtcca agcacgtact tcttgttccc cagcagtaaa
     3061 gtaagtagct aagcctaaca aatcataagc agcacggatc aactgatcca aacctgattc
     3121 ttcgattcct aaagcttcta aaaattccgc tttgtcttct tcatctaatt ctgcgatttc
     3181 ttcttctgca cgagcactga ccacgatcac ttctgcattt tcttctgcag caaagttgcg
     3241 cacttcttgt acataatgat tcgcgtctgc atctgctacg tcatcttctg agacattggc
     3301 tacataaaga attggttttg tcgtcaataa aaatagtgat ttaacgattt tttgttcttc
     3361 ttcagtaaat tcgatcgttc gggcagattt tccttcttcc agtacaggtt tgattttatc
     3421 cagtacagct agttctgcca ctgcatcttt atctttggtt ttagcaactt ttgctacacg
     3481 agtatagcgt ttgttgatag attctaagtc tgctaacact agttccaagt tgatcgtatc
     3541 aatatcttct agtggatcaa cacgtccttc tacgtgagta atattatcat catcaaaaca
     3601 gcgaacaacg tgacaaatag cgtctacttg gcggatatgg cttaagaatt gatttcccaa
     3661 accttctcct ttacttgcgc cttttacgat tccagcaata tctgtaaatt caaaagtcgt
     3721 cggaacagtt tttttcggat gtacaagttc tgttaagcgt tgcaaacgcc agtcaggtac
     3781 ttctaccatc cctacgttgg ggtcgatcgt cgcaaaggga tagtttgctg cttctgctcc
     3841 tgcttttgtg atcgcattaa acaaagttga ttttcctacg ttgggcaacc caacaattcc
     3901 agcagtcaat gccataaatt tattcactct ttctctgcat ttttttcaat tacttttttt
     3961 aatttctttt caaaatctcg acgggtcatc atgacgatat gtccgcaatt catacatctg
     4021 attttgatat ctgcgcccat tcgaatgact tcccagcgat tcgtctggca agcgtgaggt
     4081 tttttcattt caacgatatc gtgcaagtcg tacataaaaa tagcctcctt tttgtttatt
     4141 cttcatcaaa ttgaatattc aagatatcaa gaattcgagt caaatctttt tgagaaagat
     4201 attcaatctc gatcttacct ttcccatttt tttcttggat agctacactt gtaccaaatt
     4261 tatccatcaa acgatcttcg ctttctcgga tataatatgg tttttccttt gctagccttg
     4321 ggattttttt cttttctttt ccatcatttt gatttaactc agaaacaagc tgttccagtt
     4381 ggcggacagt taaattttca gttactgcac gattggctaa tttcaagatc aatgttttat
     4441 tttttaaacc taacagcgta cgggcttgtc ccatagataa acgctgatct tgtaccattt
     4501 ccttgacaag atccggtaaa gaaagcaagc gcaaataatt ggcgatataa ggtctgctct
     4561 ttcctaaacg actagctact tctgcttgtg ttagtttcag gtttttcatc agcatctcat
     4621 atgcttctgc ttcttctaac ggattcagat cttctcgctg caagttttcc agcactgcta
     4681 cttgcatcat cgcttcttcg tcaaagtctc taacgatagc agggatcgtt tctttttcag
     4741 ctagtttgga cgctcgaaaa cgtcgctccc ctgcaataat ctcatatcct tttactgcgg
     4801 aacggcgtac gatgatgggt tgaaagacac ctgattgttc aatagaatta gctagttcct
     4861 gcaaagatac ttcttcaaat gttttacggg gctgatacgg atttggtcgc agctcattca
     4921 atggtagctg gacaacggta tcatctttta catccaccgt ctctaagttt tctaaatctt
     4981 gaaacagtgc atcgattcct cggcctaatc ctttactttt cttcacgact taccacttcc
     5041 tttgccaatg cttggtagac ttcagctcct cgagaacgtg gatcgtagtc gatgatcggt
     5101 tttccatgac taggtgcttc tgataaacga atatttcttg gaatgatcgt ttcgtaaact
     5161 ttttcgcgga agtatttacg tacttcttct acgacttcat ttcccagatt tgttcgtgca
     5221 tcatacattg tcagtaagac tccctcgatc tctaattctg gattaaagtg tttttggact
     5281 aaacgaaccg tattcagtaa ttggcttaat ccttccaatg cgtaatactc acactgaaca
     5341 ggtatcaaaa tcgaatcact tgctgtaaat gaattgattg tcagatggcc aagagaaggc
     5401 gggcaatcga tcaaaatata atcatactga ctgcttactt ctgctaaaga tccttttaat
     5461 cttgattctc ttgccatcat tgacgtcaat tcgatctctg ctcctgctaa ttggagagtc
     5521 gcaggcacaa tactcaaatt ttcgtgttca gtgatcaaag ttgcctcatc aattggcaat
     5581 tcattgacta gaacatcata gatgtctctt gtcacatcag gttttctgat cccgacacca
     5641 ctggtagcat ttccttgtgc atccatatcc actagcaata cttttttgcc aaggctagca
     5701 agacaagcac ctagattcac cgtcgtcgtt gttttgccga cgccaccttt ttggttcgca
     5761 acagatatta tttgtgccat ctcttctcct cctatttgat tggctgctta ttaggcagtc
     5821 cgggctttct tgggtatttc tttggggttg gtttcttttt ttgaataacg atgatatgcc
     5881 gttgatcaga gacattcggc aaggtaaccg cctcttcttt gaggaattta ccacctaata
     5941 aagcaatcgc ttgttttgct tctgtcaatt cctcttcact ttttgctgct ttcaatgcat
     6001 aaaaatagcc ttcttgttta gccaagggca aacacaattc cgctaacaca ttcaaacgag
     6061 caaccgcacg agcagtgaca aggtcaaatg atgcacgaaa gtgaggattt tgcccaaatg
     6121 tttctgcccg gtcatgatat aaggaagcat cgattcctaa taatcgggtt aactcagata
     6181 agaaggttat tcgtttattc agagaatcaa cgatcgttat ctgcagttct ggaaaggcaa
     6241 tttttaaagg tatgctagga aaccctgccc ccgaaccaac atcgcataaa gataaaggtt
     6301 gcgtaaagtc tacttcaaat gctaatgtaa gtgaatcgta aaaatgcttc agatatacgt
     6361 ctttttcatc cgtaatagct gtaaggttca tcttttcgtt ccattcgact aatgtccgat
     6421 aataaatagc gaattgattc atttgatgat cggtaagctc tatccctttt tctgccaagg
     6481 attggcgaaa ttcttctggt atcataaata ttcctttcat tgtgaaacag caattgtttc
     6541 acagattctc tccctacttt aacgcaaaat ctctagacat gcaatccttc catatggatt
     6601 cttaaaaatt tgaaaagtaa gaaaagccga tagacttttt ctttctagta tgactcataa
     6661 aatatacaca gaagagagaa ctagctttga gcaatttctg caaaaactag ttctctcttc
     6721 tatttattat tacgtattac gctggttcac tgactttcgc aatcttccct tgttcgatat
     6781 agaccattag gatacttagg tctgcagggt ttacgccact gattcggcta gcttgggcaa
     6841 ttgtttctgg ttggattttc tgcaattttt gttttgcttc tgttgctaat ccgttgattg
     6901 ctgcgtagtc gatgttttct ggaatctttt tcgcttccat gcgttttaat ttttctactt
     6961 tttccatggc ttttttgatg tagccttcat atttgatttg gatttctact tgttcgattt
     7021 cttttcgtgt caattcttca ttttctggaa taaaccgtag aagttctgca taagtaatct
     7081 caggacgtct taaaaagtcg cttgctagta caccatcttt taatggtgcc gcattaatcg
     7141 ttgctaaaaa gtcttggact tcttctgttg gtttgattcg tacattcatc aaacgtttga
     7201 tttcttgttc aactgcttct tttttcttca aataattctt gtattgatct tcttttacta
     7261 agcctacacg gtgacccatt tctgttaatc gcaaatctgc attatcatga cgtaaaagca
     7321 gacggtattc agcacgtgaa gtcagcaaac gataaggttc gttcgttcct tttgttacca
     7381 aatcatcgat catgacaccg atgtaaccgt cacttcgttt gatcactaaa ggttcttttc
     7441 cctgaacttt caaagctgca ttgataccgg caatcagccc ttgtccagcc gcttcttcat
     7501 aaccgcttgt accatttgtt tgtccagctg tataaagatt ttcaacgact ttagtttcta
     7561 atgtcggacg gagctggtgt ggctctacta cgtcatattc gatagcatat cctgtacgca
     7621 tcatttctac tttttctaat ccagcaatag aatgaagcat gttgacttga acatcctctg
     7681 gtaaagaagt agataaacct tgaacataga cttcttccgt atttaagcct tctggttcca
     7741 aaaataattg atgacgtggt ttgtctgcaa aacgcacgat cttatcttcg atggatggac
     7801 aatagcgagc gcctacccct tcaacgatcc ctgtaaacat tggggcacga tgtaagttgt
     7861 ctcgaataat ttggtgagtc gtctcacctg tataggtcag ccagcaagat tcctgatcta
     7921 gtttataggc actatctggt gtgctgaagc taaaatgatt cggctctttg tcaccaggct
     7981 gctcttctgt aacagaatag tcgatcgtac ttgattttac tcgaggcggt gttcctgttt
     8041 tgaaccgttc gatagcaaag ccaagttctt ttagatgatt cgctagtcca atagaaggtt
     8101 gagagttatt cggacctgat gaatatttca attcaccgat aatgatttct ccgcgaagtg
     8161 ctgttccggc tgtaataaca actgctttgg cccggtagct cgctcctgtg gacgtcacta
     8221 ctccatgaca aacaccatct tcgacgatca gttcttcgac gattccttgt cttagcgtca
     8281 aatttggttc tttttcgatc gtatgtttca tttctgttga ataagcatgt ttgtctgctt
     8341 gtgctcgcaa tgctcggaca gctgggcctt ttcctgtgtt caacatacgc atttggatat
     8401 aggttttatc gatattctta cccatttctc cgcctaacgc atcgatttct cgaacgacaa
     8461 cgcctttagc tggtccgcct acagaaggat tacatggcat gaatgctacc atgtccaaat
     8521 ttattgtcag taataatgtt tttgatccca tacgtgcagc agcaagtgca gcttctgaac
     8581 cggcgtgtcc tgcgccaaca acgatcacgt catacgcatc tgcttcataa tgttccaatc
     8641 gtttgttcct ccttttattt tcctaaacaa aattgactga ataattgagt gattagctca
     8701 tcttgtacac tgtcgccgac aacttctcct agatagtccc agcaacgcgt catatctatt
     8761 tgaacgagat ccacaggcat tcctgaatca atacctgcaa tgacttcttc aagtgagagg
     8821 gaagcttttt ctaacaacgc gatatggcgg gtattagaaa cataagtagc gtctctttct
     8881 cctgtttctc cgctgaagaa taaatcagaa atagctgatt ccaaacgatc tagtccgtcg
     8941 tttttagcta cggaaattga aaaaactggt tcattttcga tcaatttctt caatttttct
     9001 tgttccagct gtgctggcaa atctgtttta tttagaagaa tgatccgttt caatccactt
     9061 gtcgcttcca ataattgttc atcttctgct gtcagtggtt cgctttggtt tagaacaagt
     9121 aagatcaagt ctgcttctgc taatgctttt cggcttcttt cgaccccgat ccgttccacc
     9181 acatcttctg tttcccgaat tccagctgta tcgattagct tgagcggtac cccccgaaca
     9241 ttgacatact cttcgattac atctcgagtc gttcctgcaa tatccgtaac gattgctttt
     9301 tcttctctta acaaatggtt taacaaactt gatttgccga catttggccg gccgatgatt
     9361 gccgtactta acccttcccg cagaaccttc ccttgcttgg atgtagcaag tagcgcttgg
     9421 attctttgtt ggatcatctg cgctttttca agcaataact tcgtagtcaa ttcttcgaca
     9481 tcatcatatt ctggataatc aatatttact tctacttgtg ctaatgtctc taaaatctct
     9541 tgtctcaatg agcggatcaa agcagacaga ttgccgtcta actgattaag agctagtccc
     9601 attgctttgt ctgtttttgc ccgaatcaaa tccatcacag cttctgcctg tgaaaggtca
     9661 acacgaccat tcaagaatgc tcgttttgtg aattcgcctg gctcagctaa tcttgcacct
     9721 tctcttaaca atagctgcaa aatttgattg actacaacga tcccaccgtg acaattgatt
     9781 tctactacat cttcccgcgt aaatgtcttt ggtgctctca tcacggagac catgacttca
     9841 tcgacaagct gattgctctt gggatcaacg atatgtccat aatggatcgt atgacttggt
     9901 acttctgata atcgtttgtt tccagattga taaactttat ctgctagttg cacagcttga
     9961 tcgccactta aacgaacgat actgattgca ccttctccag gtggggtaga aattgccgca
    10021 atcgtatcaa attctaaagt aatttcagcc attttttcac ttcctttttc attttgcgca
    10081 caaaaaaagt gcccactcca ccctttatgc acaataaacg gtgaacttcg cactttgact
    10141 gcttgttctt gattaaattc tggtcataga ttatcacact tgctataagg aatcaagtgt
    10201 ttaaaacaat tagatgaagt tgagcctgtt ctgcttccat taccttatat ttaattgtcc
    10261 ttggatgtct ctttgcgttc tttggtttat tcgaagagaa gatactgtat aaacaaggct
    10321 ttatctttct taaaaaaaac ggtacactaa atggtagcgc tatctaaact atacactttt
    10381 gaaaggagaa aatatgtgag cccgttcaga tctgctgcat tggaagaaga aagtgaccct
    10441 cggatcaacg atgtcgtttt atctacaggg aatatcaacc agaaatatat cgtccgcgat
    10501 atcgtttttg ttgtggaatg cttagaagct gatttgtttg acccatcttt tcccaaagat
    10561 gaccttttct taacaacgaa gaggaaatta aagacgaagg tacttgaata tggtgcgaat
    10621 gcagtaatca actgtcattt tgagtatcag caaaaaaaac gcgacggaaa gtattttctg
    10681 gaactttttg cttatggaac agtgatccaa tttatccaaa caacgattgg ttaaatgaaa
    10741 cagacaaaaa aagcggatca aaactgaaga cagtttcgat ccgctttttt ctatcaaagt
    10801 tagtgactac ttcatcgtat actctgataa gaatgatttc tagtaaaata tacttggttt
    10861 gaaaaacttt gtcaacgtga tttattcaaa aagtaatgga atcaataata ttttttagca
    10921 ggttctacta ctaaataacg ataaggttcc tcaccttccg aatgtgtttt tacatgttca
    10981 tctttgctta atgcagcatg gatttgttta cgttcaaatg caggcattgg ttctaagaaa
    11041 acaggctgcc ctgtccgttt tactttttca gccgtgcgat cagctaaacg ctgaatgatc
    11101 tcttggcgct tttcacggta attgcctaca ttgactacta cagacagctt atttcttgct
    11161 aaacgatgga tgaagacttg tgccagatat tgcaatgcat tcagtgtttt tccatgtttc
    11221 ccaatcagta tgccttgctt ttgtgtttct aaatggaaaa caaccatatt atttgattct
    11281 ctttccattt tgacaagagc tggagcatca agctgttttg aaatttcagt aagataaact
    11341 gccaattccg ttaaagctgc ttcatcacct agctcactta cttcttctgt tttttcttca
    11401 agaatcgttt cgttgactac ctcgatctca gctgttggtt cttcttccaa aatttcttct
    11461 acagtctgtt ctactgtttc agaaactttt tcgctgatac ttggctggat cgaaagccgt
    11521 gcattctttc gacccattcc taggaaacct ttttttcctt cttccagtat ttcgatttcg
    11581 acttggtctt tggccaaacc caaatcagcc agacctagtt ggacagcttc gtctattgtt
    11641 gcagcttcat aaatcggcat tagcattacc tcccctatta tttccgtttt ttcttaggat
    11701 tcattgcttt cttaagagca cgttctcttt cgcggattct ccgtgcttct tcttcacgct
    11761 cttttcgaat tttgaaaggg ttgttgatca gcagcgtttg tacaacttgg aaggcattgg
    11821 aaactaccca gtataatgaa agaccgctgg ctaaattgac acccatcact aaaatcatta
    11881 caggcatcac gaaattcatg atcttcattg atgcattcga ttcaatttga ctcatgctag
    11941 ataaatacgt acttgcaaaa gtaaagattg ctgctaaaat cggcaaaata aatgttggat
    12001 ccgcgttccc taagttcaac cataagaaat gcccttgttt caactctggt acacgtgaaa
    12061 tagattgcca taacgccatc aagattggca tttgtactaa taaaggaaga caaccagcat
    12121 atggattgac gccattttct gcatataaac gctgctgctc ttctcttaac ttactttgtg
    12181 tttccggatc tcttgaacta tattgttgct gcagtgcttt taatttcggt tgtaattctt
    12241 gcgttttacg catgctcttt gtttggaaat gcatcaacgg caataggatc acgcggatga
    12301 tcagtgtaaa taaaatgatc cctatccctg cattaccaaa tgacaacgcc ttgatcgcct
    12361 cagcaaagta ataaacaata taacgatccc aaattcctgt actctgtgcg ctgacttccc
    12421 cagttccgca accggataag acgatgacca aactaacgat accggccatc aaaagtaaac
    12481 gtttgtattt cttcacttac tcttttcctc tctgtcgatt atttttgcaa gttttaagac
    12541 gtggactaaa ttggagcgaa cctcatcata agtcaacccc ttcacacttg gtctagcaat
    12601 cacaataaaa tccaactccg gatcaatttc ttcttttata gaataaactg ctgctcggat
    12661 ttttcgtttg acttcattgc ggtttaccgc gttgccgacc ttttttccta cagataaacc
    12721 aactcgaaaa tgaggctgtc ccggtttttc caaacggtaa acgacgaatt tgcggttagc
    12781 aaaagaatct cccgtatgga acacggcttg aaactctcgt tcttttttta ctcgatacgc
    12841 ttttctcatt agttttcttt ccttttctat ctctcactta cgctcataat cataccataa
    12901 ttacgattgt cctttcatca tttccctaaa aaagagtata aaaaaaacca ctgaaacccc
    12961 agtggcctaa gctgaaagaa cttttcttcc tttgcgacga cggctagcta acacacgacg
    13021 tccattttta gtactcatac gtttacggaa tccgtgaact ttttgacgtt tacgtttatt
    13081 tggttggtat gttcttttca tatattccac ctccaaaatg ttcttatcta ttttataaac
    13141 acagacatac tttgatagta taacgacaaa gtagtgattt tgtcaatata aaatagaaga
    13201 tcgattgtta aaacttatcc acaagattat ttttttctat gggaatccta tgtggaaaaa
    13261 gttatgcaca gggattatcc acagataata aaaggctggt tttacacaga aaacacacgt
    13321 gtaaaaaaag taatccacaa tcaggcgatt tcctgtgtat tccgtctcct aactattggt
    13381 atatctgtat tttttatcca cagacgcaag aggaaatcta ttggttttta cgagttttcc
    13441 acctgtgcat tagtggtgtg gaaaactttt tttgacaact gtgtttttct cttttttctt
    13501 tttgtcgatt gtgtggataa ttgtaattaa aaaatttttt tcttcggttt ctgtggaaaa
    13561 ctattgaaaa aaatgctaaa ttagtactag ttattcactt tttaatgaag gaggaggcct
    13621 tatatggtat ccctcgatgc tttatggaat gaattaaaag caacatacca aaaggattta
    13681 tcgcctgcta gctataatac atggatcgaa acagcgaacc ctcgaaccct tgatcaaaac
    13741 cagctcgttg ttgaggttcc tagcaagatt cataaagaat attgggaaaa aaacctggcg
    13801 acaaaaatcg ttgaagtcgg ttatatgtta tcaggaaatg agattatccc tcgctttatt
    13861 actggcgaag aagcagagca agaagaagtt atagaagaaa aaaatccaaa agttgtggca
    13921 cctagtccgc taaaaaaagc catgctgaac cctaaatata cctttgatac gtttgtcatt
    13981 ggtaaaggaa accagatggc tcatgcagca gcgctcgttg tagcagaaga tccaggttct
    14041 atttataacc cgctcttctt ttatggaggc gtgggacttg gtaagactca cttgatgcat
    14101 gcaattggtc atcaaatgct gcaaagtcag cctaatgcca aagtaaaata tgtaagcagt
    14161 gaaacttttg ctaatgattt catcaattcg atccaaaaca aaacagcaga agagttccgt
    14221 caagaatatc gaaatgttga tttactgcta gtggatgaca ttcaattttt tgcagaaaaa
    14281 gaagctacgc aagaagagtt tttccatact ttcaatgcct tgtacaatga agggaaacaa
    14341 atcgtactaa ccagtgatcg gttgccaaac gagattccga aactgcaaga acgccttgtt
    14401 tctcgctttg catgggggct gtctgttgat attacaccgc cggatcttga aacaagaaca
    14461 gcgattttac gtaaaaaagc ggcggctgaa cgtctagaga tcccagatga cacactaagc
    14521 tacatcgcag gacaaattga ttctaacatt cgtgaattag aaggtgcgct tgttcgagtg
    14581 caagcttttg ctgcgatgaa tagtgaagat atttcgacta gtctagctgc agacgcactg
    14641 aaaacgttaa aatcaggaaa aggacatcct caattgtcaa tcctgcagat ccaagaagaa
    14701 gtggcaaagt attatcacat ccaattgaaa gatctcaaag gaaagaaacg cgtcaaatct
    14761 attgttgttc ctagacaaat cgctatgtat ttggcacgtg agctcacaga taattcttta
    14821 ccgaaaatcg gagctgaatt cggtggcaag gatcatacaa cggttatcca tgctcatgaa
    14881 aaaatccagc agctgatgga ttctagtgtc agtatgcaaa atgaagtatc agaaatcaaa
    14941 aactttttac taaattaatt tgtcgattct atcaactgaa aatagcatgt ggataaaaga
    15001 aaaaaacgtt caaaagttat acacactttt tccacagctg ttttttcgtt tctctcttac
    15061 gttttttgag ttttccacag aatcaacatg ccctattact tttattattc tttttaacta
    15121 ataataaata aacaaacatt caaaggagat acatcatgaa agttacttta aaccgagcta
    15181 gctttatgca ggaattgcaa actgttcaac gagctatttc aagcaaaacc acgatcccta
    15241 ttttgacagg tgtaaaaatc acactgacac aagaaggttt gactttgacg gggagcaacg
    15301 ctgatatatc aattgaaact tttttgtctg ttgaaaacga aaaagcaaat atgcaaatcg
    15361 aatctactgg ttccattgtt ttacaagcac gtttctttag cgaaatcatt cggagacttc
    15421 ctgaagaaac atttacttta gaagttttag aaaataaaca agtagcgatc acttctggaa
    15481 aagcgaattt tatcgtaaat ggattagatg cagataacta tcctcatctt cctgttgtcg
    15541 aaagccataa ccagatgaaa ttacctgtac acgtattgac taaactaatc aacgaaacag
    15601 tttttgctgt ctcacaacat gagagtcgtc caatcttgac aggtgtgcat ttcattttat
    15661 ctgataattc tttattagct gtagctactg attctcaccg tctaagtcaa cgcgtgattc
    15721 cagtagaaca agcggctgat cattttgata ttgttattcc tggaaaaagt ttgatcgaat
    15781 tatctcgctc attaacaaat gaagaagaaa tcgtcgaaat cagcattatg gaaaaccaag
    15841 tgttgttcaa aacagaaacg atgtatttct attcccgttt gctagaagga aactatccag
    15901 ataccaatcg tttgattcct tcaagtttta atacagaggt tgaattttct gttcctagct
    15961 ttttagcggc gatcgaacgg gcttctttac tttctcatga aggccgtaac aacatcgttc
    16021 gtttatctat tcgtccagat gcggttgttt tatacggaaa ttcgccagaa atcgggaaag
    16081 tagaagaaag cttgagttat acagcaagca gtggcgatcc attagatatt tctttcaatc
    16141 cggattatat gaaagcagcg ttgcgtgcat ttggagatat gagcatcaaa gtgaaattta
    16201 tctctgctat tcgtccattt acattggaac caacggaaga tggcgttcaa tttattcagc
    16261 tgattactcc tgtacgtaca aattaacaat gattttcaat gttcttgaaa atttaattga
    16321 aaagaaatag aaaaaataaa attttaaaca gaaggcccta aaatctcttt taaggctttc
    16381 tgtttatttt tgtttaaatc acctttttta gattaaatcg tcttatatgg aaaaatatat
    16441 ggataaattt gttttattgc gaaaaaaaag gtataataga gtatactttt aataatgaaa
    16501 atgagggatg ggcattgaaa caacaagtca ttctaaatac ggaattcatg acgttgggcc
    16561 aaatgttgaa agaagtcaca gttatcggta gtggcggaca agcaaaatgg tatttggcag
    16621 aaaacactgt gttagtcgat ggcgaaccag aaaatcgtcg tggacgcaaa ctttatcccg
    16681 gcatgatggt tgaagttcca gaagtaggaa ctttttttat ggtaaaaaaa ggaaacgacg
    16741 ataatgaggc tgaataagct gtatttaaaa aattatcgaa attacgaaga gctgaacatc
    16801 gaattttcca agaacctcgt catcttttta ggagaaaatg cgcaaggaaa aacgaatctt
    16861 ttggaaagta tctacgtatt agctatgacg cgaagtcatc ggacaagtag tgagcaggaa
    16921 ttgattggct ggactgacga tcaggcgatg attcaaggag agatcacaaa aggttcatcc
    16981 actcttccat tagaaatctt attatctaaa aaaggccgaa aaaccaagat caaccatatc
    17041 gaacagaaaa agttaagtac ttacgtggga caaatgaatg tcattttatt tgcaccagaa
    17101 gatctttctt tagtaaaagg cagcccgcag accaggcgga agtttttaga tatggaatta
    17161 ggccagatca atccaatcta tctttatgat cttgtccaat accaagcaat tttgaaacaa
    17221 agaaaccagt acttgaagca attgaatgaa aaaaaacaaa ctgatttgct ttatttggat
    17281 attttgtccg aacaactagc agcgtttggc agcaaagtat tgaaagcaag agcacagttc
    17341 gtcaagcgat tggagttttg ggctaattct ttgcatcagc aaatcaccca tcaaaaagag
    17401 cagctggaaa tcgagtatct caccgcagtc gattctttag aaacacatac gcaagagcaa
    17461 atccaagaac aatttctcgc acttttgaac caaaataaaa agaaagacct ttttcgggga
    17521 acaacgacag ttggtcctca tcgtgacgat ctttcctttt ttattaatca gaaaaatgtg
    17581 cagacttatg gatcgcaagg acagcaaaga acaactgcac taagtgtcaa attagcagaa
    17641 atcgatttga ttaaagaaga gacaggggaa tatccaatcc ttttgttaga tgatgtgatg
    17701 agcgagctgg atgataatcg tcaactccat ctgctagaaa caatcgaagg aaaagttcaa
    17761 acgttcttaa caacaacgac acttgaccat gtaaaaaata aaatgactgt tgaacctgag
    17821 attttttatg ttcaacaagg gaaactaaaa ggagaagaaa ctgaatgaca gaagaaagaa
    17881 gtttagtaga acgcgctaaa gagtatgatg ccagtcagat tcaagtactt gaaggacttg
    17941 aagccgttcg taaacgacct ggcatgtata tcggttcgac tagttctgag ggtctgcatc
    18001 accttgtttg ggaaattgtc gataattcga tcgatgaagt attagcaggt tttgcaacga
    18061 aaatccatgt gattattgaa aaagacaaca gtatcaccgt tattgacgac ggtcggggga
    18121 tacctgtaga tatccaggca aaaactggac gtcctgcagt tgaaacggtc tttactgttt
    18181 tacatgctgg aggaaaattc ggcggtggtg ggtacaaagt ttctggtgga cttcacggag
    18241 taggatcttc tgttgttaac gcgctttcta cacagcttga tgtcaaagta tacaaagaag
    18301 gaaatgtgta ctatcaagaa tatcgtcgtg gagctgtagt ggacgactta aagattatcg
    18361 aacaaacgga tcgccatgga acaacggttc actttacgcc agaccctgaa atttttacag
    18421 agacaactga gtttgatttt tcaaaattgg ctacccggat ccgtgaactt gctttcttga
    18481 accgcgggat gcgtatatcg attgaagaca aacgagaaga agaaccagtc atcaatgaat
    18541 accattatga cggcgggatt aaaagttatg tcgaatactt gaatgcaaac aaaaccgtga
    18601 tttttccaga acctgtatat ttggaaggtg aacagcaaga tatcgcagtt gaagtctcta
    18661 tgcaatatac agacggctac cattccaata tcatgagttt tgccaacaat atccatacgt
    18721 atgaaggcgg aacacatgaa tcaggattca agactgcttt aactcgtgtg ataaatgatt
    18781 atgcccgaaa acaaaagctg atgaaagaaa atgacgacaa cttgaccggt gaagacgtgc
    18841 gagaaggatt gacagctgtt atttctatca agcatcctga ccctcaattc gaaggacaaa
    18901 caaaaacaaa attgggcaat tccgaagtac ggacagtcac tgatcggtta tttagcgaac
    18961 atttcatgaa attcttgctg gaaaacccaa gtgtgggccg tcaaattgtt gaaaaaggat
    19021 tactagcttc cagagctcgt ctagcagcga aacgtgcgcg tgaagtaacg agacgtaaag
    19081 gtgctttaga gattagtaat ctgccaggaa aattagcgga ctgctctagc aacgatcctg
    19141 aaaaatgcga attgttcatc gtcgaaggag attcggccgg cggatcagct aagcaaggtc
    19201 gtaatcgaga gtttcaagcc atcttgccta ttcgtgggaa aatcttgaat gttgaaaaag
    19261 caagcatgga caagatcttg gcaaatgaag agatccggtc tttatttact gctatgggta
    19321 cagggtttgg agaagatttt gatgtatcga aagctcgcta ccacaaatta gttatcatga
    19381 ctgatgccga tgtcgacggc gcgcatatcc gtacattgct gctgactctt ttttatcgtt
    19441 acatgcgtcc tattgttgaa gctggatacg tctatattgc tcagccacct ttatacgggg
    19501 taaaacaagg gaagaatatt acgtatgtac aaccaggaaa aaatgcagaa gaagagttga
    19561 aacaagtcgt tgcttcactt cctgcctcac caaaaccaag cgttcagcgt tataaaggac
    19621 ttggagaaat ggatgatcat caactatggg aaacaactat ggacccaagc aatcggatga
    19681 tggcccgcgt cagtgtggac gatgctattg cagcagatca gatatttgaa atgttgatgg
    19741 gggatcgagt agaaccccgt cgtgcattca tcgaggaaaa tgcacactat gtgaagaact
    19801 tagatattta atcatgaagg aggaaaaaga atgagtgaag aaatcagaga aaacatccat
    19861 gatgtcaatc taaccagcga aatgaaagac tccttcatcg attatgcgat gagtgttatt
    19921 gtcgcacgtg cacttcctga tgtcagagat ggtctgaaac ccgttcatcg ccgtatttta
    19981 tacggcatga acgaattagg tgtaacaccg gataaagccc ataaaaaatc tgccagaatc
    20041 gtcggagatg tcatgggtaa ataccatcct catggagact atgcgatcta tgagtcaatg
    20101 gtacggatgg cacagccatt cagctaccgt tatatgctag tggatggtca tggaaacttt
    20161 ggttctgttg acggtgacgg tgccgccgct atgcgttata ccgaagcacg gatgagcaaa
    20221 atcgctacag aaatgctgcg tgatatcaat aagaacactg ttgatttcca aagcaactat
    20281 gatgatacag aaaaagaacc agttgtacta cctgctcgct tcccgaatct tttagtgaac
    20341 ggaacaacgg ggatcgccgt aggtatggcc acgaatatcc cacctcataa cttgtctgag
    20401 gtagtagcgg ctatcgattt gctgatggat aatcctgatg tgacgaccaa tgaattgatg
    20461 gaagtattac ctggaccaga ttttccaaca ggtggtttgg ttatgggaaa atcaggaatc
    20521 cgaagagcgt atgaaacagg taagggttct attaccgtac gtgcaaaagt tgagattact
    20581 gagatgccaa atggtaaaga acggatcatc gtgacagaat tgccttatat ggtcaataaa
    20641 gcaaaattga tcgaacggat ttctgaactg cacagagaca agcgtatcga agggatcaca
    20701 gatttgcggg acgaatcttc ccgtgaaggt atgcggatcg tcattgacat ccgtcgtgac
    20761 gccagcgcat ctgttatctt gaataactta tataaattga catccttgca aaattcattt
    20821 ggattcaata tgttggcgat cgaaaaaggt gtgccgaaag ttttgagctt gaaacaaatt
    20881 cttgaaaact atatcgaaca tcagcgcgaa gtcatcacaa gacggacagt ctttgaaaaa
    20941 gaaaaagcag aagcaagggc acacatttta gaaggtttgc gtattgcttt ggatcatatc
    21001 gatgaaatca ttgcgattat ccgcgggtct aaatcagatg acgaagcaaa agcgacgatg
    21061 atcgaacggt tcgatttatc cgatcgccag tctcaagcta ttttagatat gcgtttacgc
    21121 cgattgaccg gtttggaacg ggaaaaaatc gaaaatgaat accaagaact cttaaaactg
    21181 attgaagatt taactgacat tctggcaaga ccagaacgtg ttacagaaat catcaagaat
    21241 gaattagcag acttgaatca acgatttggt gataaacgac gcacagaatt actagtcggt
    21301 gaggtcttaa gtctggaaga tgaagattta atcgaagaag aagaaatcgt tattacattg
    21361 acaaacaatg gttacatcaa acgtttggca aataatgaat tcagagctca acgaaggggt
    21421 ggacgtggtg tccaaggaat gggtatccac aatgacgact tcgtcaaaaa tctggtttct
    21481 tgttctaccc atgatacatt gttattcttt acgaataacg gaaaagtgta tcgggcaaaa
    21541 ggatacgaaa ttccagaata cgggcgcaca gccaaaggaa taccaattat caatttacta
    21601 ggtatcgatt cgagtgaaag catccaggca atcattgcgg tgacgggaga agcagaagaa
    21661 ggccactatc tcttctttac gacgcgtcaa ggtacagtaa aacgtacttc tgtcactgct
    21721 tttgctaaca tccgaagtaa tggtctgatc gcaattggtt tgaaagaaga cgatgagctc
    21781 gtcaatgtgc tactgacaga tggtcaatct aatatcatta ttggaacaca taacggctac
    21841 tctgtcactt tcaaagaaga agcagtccgc gatatgggac gtacagcttc cggggttaga
    21901 ggaatacgcc tgcgtgagga agattatgtc gttggggcag ccttaatgaa ggaagatcaa
    21961 gaagtattag tgatcacaga aaaaggttac ggaaaacgga caaaagtatc ggaatatcca
    22021 gtgaaaggcc gcggaggtaa agggatcaaa acggcgaaca tcactgaaaa aaatggtcca
    22081 ctagctggat tgaccactgt ttctggagat gaagacatca tgctgattac agataaaggt
    22141 gtcattatcc gtttcaacgt atcgactgtt tctcaaactg gacgttcaac attaggcgta
    22201 cgtttgatga agatggaagc tgatacgaaa gttgtcacga tggcagcagt cgaaccagaa
    22261 gctgcagaac aaacagttga agaacaagga tcagaagaat agccatcaag actaattgtg
    22321 taagctagca agaatgaccg attaaaaaat ctggttattc ctgctggctt ttttgattag
    22381 ttgaatttct cttaaaatat tcgaaactgt tcattctgta ttgcttttga ccaaaataga
    22441 gtgtataatc agagcttgtg agtagtctaa ttaattagat aactctcctt gctcttagga
    22501 acctaagagc cgaaagtcca cagggaggtg aatatcaatg gaaaacacga aatatgaaat
    22561 catgtacatt attcgtccaa acattgatga agaagcaaaa actgctttaa tcgaacgttt
    22621 cgatgcaatc ttgaaagata acggagcaga agttatcgaa tcaaaagatt gggaaaaacg
    22681 ccgtttcgct tatgaaatga acggttaccg tgaaggtatc tatcacatcg ttaaagtatc
    22741 ttctccatca tcagcaaatg ctgtcaatga atttgaccgt cttgctaaaa tcaacgacga
    22801 tatcattcgt cacatgattg ttaaagaaga agcttaattg ttgtttcatg tgaaacaata
    22861 gaaaacgatg agaggagatg actattttga ttaataatgt tgtattagtt ggacgtctga
    22921 cgaaagatcc agatttgcgt tacacagcaa gtggtacggc agtcgcaaca tttactttgg
    22981 ctgtgaatcg taattttaca aaccaaagcg gcaatcgcga ggctgatttt atcaactgtg
    23041 tgatttggcg caaatcagca gaaactttag caaactatgc tcgtaaagga acacttttag
    23101 gtgttactgg acgtatccaa actcgttctt atgataatca gcaaggacaa cgtgtatacg
    23161 tgacagaagt agtagctgac aacttccaat tgctggaaag tcgttctgca tctgaaaatc
    23221 gccaacaaag cggcggattc caaagttctg gtcaatcagc tggcggattt ggcggaaaca
    23281 ataactctaa tcaaacatct caatcatcca acggtatgcc tgatttcgac cgtgatactt
    23341 ctgacccatt cggctcaagt tcaacgatcg acatttcaga cgatgattta ccattctaaa
    23401 cgaatttgat aggagggaaa tagaatggca caacaaagaa gaggcggacg taaacgtcgt
    23461 aaagtagact acattgctgc taaccatatt gaatatatcg attataaaga tatcgaatta
    23521 ctaaaaagat ttatttcaga acgcggtaaa atcttgccac gtcgtgtaac tggtacaggc
    23581 gctaaaaacc aacgtaaaat tactgttgca atcaaacgcg ctcgtatcat gggcttgcta
    23641 cctttcgtta gcgaagacta ataaatccta ggaattgaat gactgatcct tttgatcagc
    23701 tattcaattc ctttttttct gtaaaaataa cctctattcg tttagtcgct cgaatgacga
    23761 aagttatggt aaaatcaaat tagtcatata tgggaggaaa attatggaaa ataaaaacaa
    23821 tcatttatcc ccgaaacctc tcttccttat cctgtttata ttaatcgaag tattggtagt
    23881 cttaatttta ccatttcgtt ttgttagcgc ttcggtcatt ctattgatga atttatgggg
    23941 tgttcgctat tggttgaaaa tgaaacgttg gcttatttta aataaacgtg aaaaaatcca
    24001 gcaggcttcg actgtagctg aaaccaatct agcttatgtc tcagaagtca tgcctgtagg
    24061 agtgattgct tatcagccat caagccaaaa aatcgaatgg ctcaatccat tagcattgaa
    24121 aatcaaagat caaagtggat taacagagga agaattgcta gatacttttt ttactgcaaa
    24181 agaaaaaaag aaaaaccaag tctatctagc agataaaaca tttcagtttg atatggatac
    24241 agtaaagggt gttgtttatt ttaatgatat tacccaaaac cagttgttaa aactccatca
    24301 gacgaacagt cagccggtga ttggtatttt atctattgat aactatgcag atgccattga
    24361 taaattggat gacaaagaga tttcttattt gaactctttc gtcactacac tagtttctga
    24421 ctggatgaat gaataccatg tctttttcaa aagaatcaac gcagaacggt ttttcttcgt
    24481 agcacagatg atcgatctga aaaagatgat ggataaaaaa tttgatttgc tggatcgctt
    24541 tcgagcagaa gctgaaaaac agagctcgcc tatcaccctt agtatgggga ttgcttatgg
    24601 ctcaagaacc ctcgatgaaa tcggtggaga agctcagaat aatttagatg ttgctttagt
    24661 ccgtggaggc gaccaagttg tcgtgaaaga ggtaaaagaa ggagcaaaac ctgtttatta
    24721 tggggggaaa tctgctaaga atgtcaaacg cacgcgtgtt cgttctcgag cgatgagtac
    24781 cgctttgcgt cggatttttg atgaaacagg cgatgtgttt atcatggggc acaagtttcc
    24841 ggatatggat gctttaggct ctgcttttgg tgtcagttgt ctggcacgct tcaaccagaa
    24901 aaaagcttac atcgttatca acgagaacga gatcattcca gatgtagaac ggtgtcttga
    24961 agaaatccat aagcatcctg aattagaaat gcaactaatc tctccagaac gtgccataga
    25021 gctgaaaaaa gaagaggacc tcctcgtgat ggtggattac cataaacctt ctctatcgat
    25081 ctctcagggc ctatatgagc aatttgataa gattgtgatc attgatcacc atcgtcgtgg
    25141 ggaagagttt ccaagtaaac ctctgctgac ttatatcgaa tcttcagctt cttcagcttc
    25201 agagctagtt tctgagctga tccaatacca aagcagcaaa acaaatcgct tagatcgttt
    25261 tgaggccaca ttattgcttg cagggatggt tgtagataca aatagtttca atgtccgtac
    25321 aactgcacga acttttgacg ttgccagcta tttaaggtct tgtggagcag acgcatcctt
    25381 agtacaatat ttattgagct cggatttagc gacatacttg gagatcagca atttgattgc
    25441 tggaagcgac tatgtgactt ctgatattgt tgtggcggca gggacagacg aaaaagagta
    25501 taatagtgtt atagcagcaa aaacagcaga tacattgctt tcgatgatca atatcaatgc
    25561 agctttcgtc attacaaagc ggacagacgg cttgattggg atcagtgcca gaagtaccgg
    25621 cacgatcaac gtccaaatca tcatggaatc cttaggtggc ggaggacact tcacaaacgc
    25681 agctactcaa ctggaaaata cgacagttga ggaaacaaaa cagaagctat ttgctgcaat
    25741 caaagaaaat atgaatcaaa tatatgataa ggagtaatcc aaatgaaagt aattttttta
    25801 caagatgtaa aaggaaaagg taaaaaaggg gacatcaaag aagttccagc aggttatgca
    25861 caaaattatc taatcaaaaa taacttggca aaagaagcaa cgaaaagcag tatcagtcag
    25921 ttagcaggac aaaagaaagc acaagaaaaa cacgaagctg aaatcttgga agaagctaaa
    25981 aagttaaaag aattcttgga aaaagaagat actgtagtcg aattgaaggc gaaagcaggg
    26041 gaagacagcc gtttgtttgg ttcgatccct tcaaaacaaa ttgctgaagg gttaaacaaa
    26101 caatacaaaa tcaaattaga taaacgaaaa atcgaattag aaaatccgat ccgttcacta
    26161 ggctacacaa acgtacctgt taagcttcat catgaggtga cggctacgat caaagttcat
    26221 gtcgtacaag aataacaaat cttgatagcg atgttcagct ggtaagtata accagaagga
    26281 aaaaagacaa accgaaattt atctgagaaa acagctgcag caatgaaagc aaaagctgca
    26341 aatcgatttc agattgattt cggtttcttt tttgggaaca gcaaaatagc ataaagaaaa
    26401 cgagtataat aaaagagaac tattttttta ttacactttc ggtacgaatg atgacttttc
    26461 tctcattttc ttgtaaaatg aagcaattga agacaaggag cgatacgtat gaatgaagtg
    26521 tggcaggatc gaatcccacc gcaaaatatt gaagctgaac aagcggtttt aggctctgtt
    26581 tttcttgacg cagaaacgat cattgatgcc atggagtaca tagagccaaa agacttttat
    26641 cgtcgtggcc atcaaattat ttttgagaca atgatcgagt taaatgatcg taatgaagcg
    26701 attgacgtgg ttactgtcaa agaccggctg gaacaagcca atttgttaga agatgccggt
    26761 ggtttaagtt atctctcaga cttggcatta gcagttccga cagcagcaaa tatcgtctac
    26821 tatgcgaaaa tcgttgaaga aaaatcattg ctgcgtacat tgatccagac agcaacagga
    26881 atcgttacga aaggattcga gcaaggagaa gaagttcaaa caattttaga tgatgccgaa
    26941 cgcagtatct tggaggtttc ggaaaaaaga aatcgaagcg gctttttatc tattgctgaa
    27001 gtactgaact ccacgattga aaatatcgat cgactagctc aaaacaatga agaaatcaca
    27061 ggtctaccaa ctggctatca aggtctggat aaaatgacag caggtttcca gcccgaagaa
    27121 ctaatcattc ttgctgcacg tccagcggta ggtaaaacag cgtttgcatt gaatattgct
    27181 caaaatgtag gaacaaaaac agatcgttct gttgcgatat ttagtttgga aatgggggca
    27241 gaatctcttg taaatcggat gctttgtgca gaaggttcga ttgaggccag ccatttacgt
    27301 acaggtcagc tttcggaaga agaatggtcg aatctgatcg ttgcgatggg gagtctttct
    27361 cgagcaaata tttttatcga tgatacacca gggatcaaaa tctctgaaat ccgtgcgaaa
    27421 tgtcggaaac tagcgcaaga aaaaggcaat ctaggcttga tattgatcga ttatttgcag
    27481 ttgattgaag gtaacggtaa agagaaccgt caacaagaag tatcagatat ctctcgccaa
    27541 ctgaaaaaac tggcgaaaga gctgaaagta cctgtcattg ctctttcaca gttatctcgt
    27601 ggagtagaac agcgacaaga caaacgacca gtgctaagtg atattcgtga atccggatca
    27661 attgaacaag atgcggacat cgtagccttc ttgtatcgag atgattatta tgaaagagaa
    27721 ggcggagatg acgatgatgg aaacgagcca aaaaatgaca acgtcatcga agtcatcatc
    27781 gagaagaacc gaagcggtgc acgaggaaca gttgaactac tgtttatcaa agaatacaat
    27841 aagttttcgt cgctttcgcc aagagaagaa ttttaaagaa gaggttgtga gccttgagca
    27901 atcccgagag ctctcgtaag aagatgcaag gagtaaccgc aggaacgact agagtactta
    27961 atttaaacag atctccaaag ggattgtgac aaaagtcttg tcacagtccc tttttccgaa
    28021 taaacggtgt tcaatcagct gacccttggt attagctcag caaacgtcaa aatatgagga
    28081 actattttga cgtttgtttc tctaatactc aggtcaaaac gctgatctta cgacctcttt
    28141 tccttaaacg gtgttctcct gccaactcct cggtcacaag tcacaatatc atcaaacatg
    28201 agaagcagtt ttttgaaatt gctccttgtg actcagagtt aaacggcagg ctcacaacct
    28261 ctttcttaaa cggtgttcaa aagcttgcat ctgcggtaat acgcccaatc aaacgaaaaa
    28321 tatgagaagc tatttttgtt tggctgttct tattacttga tgcaggacag ctttttcaca
    28381 acctctgatt cacggtgttc caaaagtagc ttcttcgaaa aataagtcga aatttcacaa
    28441 aaatttgaga agcaattttc gtacattcct tcttatttct tgaagctgac cacttctgtt
    28501 acaacctctt ttttaataac cattctaaaa agataaagtt cgttttttaa gcgtttttat
    28561 aaaataaaaa taaaaatcat tcgattttat ttgaaatatg tatctattat tgatacaatg
    28621 gttcaggatt aaataatata gaacgaggtg ttcacatgtc atctgtagta gtagtaggta
    28681 cgcaatgggg cgatgaaggg aaaggaaaaa tcacagactt tctcagtgaa aatgctgaag
    28741 tgattgcacg gtaccaaggt ggcgacaatg cagggcacac aattaagttt aacggtgtga
    28801 cttataaact gcatttgatt ccttctggga ttttttataa agacaagatc agtgtgatcg
    28861 gaaacggcgt tgtagtcaat cctaaatcat tggttaaaga attagcttat ttacatgaaa
    28921 aaggtgtaga aacaagtaat ttgcgtattt ctgaccgcgc gcacgtaatc ttgccttatc
    28981 atatcaaatt ggaccaatta caagaagatg ctaagggcga aaataagatt ggtacaacga
    29041 ttaaaggaat cggacctgcc tatatggata aagcagctcg tgtaggtatc cgtattgcag
    29101 acttattaga taaagaaatt tttgaagaac gtcttcgttt gaatctagat gacaaaaacc
    29161 gtcaatttgt aaaaatgttt gattcagaac cacttgattt tgacgatatt tttgaagaat
    29221 attatgaata cggacaacaa atcaaacaat acgtcacaga tacttccgtt atcttgaatg
    29281 atgctttgga tgcaggcaaa cgcgtgttgt ttgaaggcgc acaaggtgta atgctggata
    29341 tcgaccaggg aacttatcct tttgttactt cttctaaccc agtagccggt ggggtaacaa
    29401 tcggaagcgg tgtagggcct tcaaaaatca ataaagttgt cggcgtctgc aaagcctata
    29461 cgtcacgtgt cggtgatgga ccatttccaa ctgaattatt tgatgaaaca ggagaacaaa
    29521 tccgcgaagt aggacgagaa tacggtacga caactggtcg tccgcgtcgt gtaggctggt
    29581 ttgattctgt agttatgcgc cattctaaac gagtttcagg tattaccaac ctatctttaa
    29641 actcgatcga tgtattaagt ggattggaaa cagtaaaaat ttgtacggct tatgaattag
    29701 atggcgaact aatctaccac tatccagcaa gcttgaaaga gttgaaccgc tgcaaaccaa
    29761 tctatgaaga attgccaggc tggtcagaag acattacagg atgcaaaaca cttgcagaac
    29821 tgccagaaaa cgcacgtaac tatgtacgtc gtatctcaga gcttgttggt gtacgtatct
    29881 caacattttc tgtcggacct gatagaacac aaacaaacat cttagaaagc gtctgggcgc
    29941 aaatctaagg ataaaaacga cgactgaatc aggacgttct taccagagcg agtcgaagtg
    30001 tttatctata cgataataat aacttgaaca ctgtttattc agaataaggg actgtgacaa
    30061 aaaccgtgtc acagtccctt tttccgaa
//
LOCUS       DAFBVQ010000028        29045 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.028, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000028 DAFBVQ010000000
VERSION     DAFBVQ010000028.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 29045)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 29045)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..29045
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.028"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(105..629)
                     /locus_tag="LLC22_001474"
     CDS             complement(105..629)
                     /locus_tag="LLC22_001474"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434757.1"
                     /translation="MSEEVGIILREAVPGDAKDILLMMGQVNKETEFLVLDEAELLLP
                     PETLEEELDYIYESNNNLLLLAIYEGTIIGTASVKADSQFRLSHVGEVGISILQEYWG
                     MGLGTLMLEEIISWAKEMGVLFRLELDVQVRNERAVHLYRKMGFQIEAVMPRGARTDL
                     GEFLDVYKMSYLIE"
     gene            complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="LLC22_001475"
     CDS             complement(622..1095)
                     /gene="tsaE"
                     /locus_tag="LLC22_001475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     ATPase subunit type 1 TsaE"
                     /protein_id="HBK5434758.1"
                     /translation="MIELSGLTMTEQFAEAIGHSAMPGDNLILTGDLGAGKTTLTKGI
                     AQGLGITQMIKSPTYTIIREYSQGRIPLYHMDIYRVAASGADLGLDEYFEGDGLSVVE
                     WGNLLEEALPEDYLELILEKSDTDLEKRYVKLISYGEQSETFKQRILEKWAENHE"
     gene            complement(1218..2198)
                     /gene="pta"
                     /locus_tag="LLC22_001476"
     CDS             complement(1218..2198)
                     /gene="pta"
                     /locus_tag="LLC22_001476"
                     /EC_number="2.3.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate acetyltransferase"
                     /protein_id="HBK5434759.1"
                     /translation="MELFDSLRFKIVRRGIKIVFPEATDARILGAAARLKAEELVEPI
                     LVGNEEEIRNAAHARGIKTSSFTIISPDNYDKWDEMVDTFVERRNGKASKEQAEKILK
                     DVNYFGTMLTYMGIADGMVSGAIHSTGDTVRPALQIIKTKPGISRTSGAMIMVRGRDQ
                     EKYVFSDCAINVNPTAQELAEIAVDSAKTAELFDIEPKVAMMSFSTKGSAKSPEVDKV
                     VEATKIAKKLAPQYMIDGELQFDASYVPSVAQLKAPDSEVAGQATVFVFPELQSGNIG
                     YKIAQRFGNFEAIGPILQGLNKPVSDLSRGANEEDVYKLSIITAAQTLID"
     gene            complement(2351..3031)
                     /locus_tag="LLC22_001477"
     CDS             complement(2351..3031)
                     /locus_tag="LLC22_001477"
                     /EC_number="3.2.2.27"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBK5434760.1"
                     /translation="MKEIIHNSWQEVLSSEFSKDYYLHLREFLKKEYASQKIHPDMYH
                     IYEALELTPYEEVKVVILGQDPYHGENQAHGLSFSVQPGVKIPPSLRNIYKELYDDLG
                     IAPVQHGNLVSWAKQGVLLLNTVLTVREGQAYSHRGKGWERLTDTIIEKLNEREKPIV
                     FILWGKPAQEKIKMIDKSRHIIITSPHPSPLSASRGFFGSKPFSKTNDALLALGEEPI
                     DWQLPETV"
     gene            3157..4026
                     /locus_tag="LLC22_001478"
     CDS             3157..4026
                     /locus_tag="LLC22_001478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5434761.1"
                     /translation="MIKLIASDMDGTLLDAHMSVSPENAEAIRFANDAGVEFMVATGR
                     NYQEARAALDEVGIDCAMITLNGAQVFDKEGNSLFTVSIPNNQAISVLDILDANGIYY
                     EVATNDGLYSENQAKRIESFASMVATHLPHLTYKMAIAMASAKLELLHITYVDSIRAI
                     LEEKNLEVLKIICFHTEGPAVLGPVGKQISLLGDLAVTSSGQNNIEVNHKNAQKGIAV
                     AHVAHERGISLEEVMTIGDNFNDVSMLQVAGVSFAMGNAEIEVKDYAKYTTDTNLESG
                     VGKAILRAIAEDL"
     gene            4052..4567
                     /locus_tag="LLC22_001479"
     CDS             4052..4567
                     /locus_tag="LLC22_001479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434762.1"
                     /translation="MSEFFIQEKQLGRATRTIVKNEKGHSLFLMVGRWGTKGDALSLY
                     AMNGDLVAHIKQISLTFGTRFELYKEFEKVGTMQKIFNWPGDFYYIRRLHWTVQGDIY
                     NHQYQIHHFNQQIMKMDKATLFSGDYYVLDVSNDEDAPVCICIAAVLDYWLYRKDKSR
                     DKPVSYRLNLS"
     gene            complement(4614..5207)
                     /locus_tag="LLC22_001480"
     CDS             complement(4614..5207)
                     /locus_tag="LLC22_001480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306107.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434763.1"
                     /translation="MLEWRKGEETMIRFARKEDAPEIAPLILVILKDMELPFLKQTGE
                     QKTLEILEEAITDPNYRYSYSRGIVEEIDGKVAGVAYGYTDEEESIIDQPLVPILEKY
                     QLDASTRLFIDKETFPNEWYLDSISVSEDFRGQGIGSRLLEALPKLAKKANRSVIGLS
                     VDEKNPKAKKLYERHDFKVVGQRMISGHLYDHMQKNI"
     gene            complement(5232..5411)
                     /locus_tag="LLC22_001481"
     CDS             complement(5232..5411)
                     /locus_tag="LLC22_001481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434764.1"
                     /translation="MEKMKCPNCGKKFAYEEVNNVVEHNDKEMPVVCPYCRTEAARIV
                     THGYFITEKIEDFLK"
     gene            complement(5488..5997)
                     /locus_tag="LLC22_001482"
     CDS             complement(5488..5997)
                     /locus_tag="LLC22_001482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326315.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434765.1"
                     /translation="MKKMMFGVAALIVIGITGMTGLLNAAFHMDDISDQEYRISLKKA
                     AAIVKNETKEHNISAIHFAVEKDLENPTNATYEYQFFCEGQVIAVNPSTGKTTVRNDT
                     EKAAEHLFDIEKTEEFKQPQAAMKEAVSYYGKKAKVKEWTLLVKDERPYYKVRLIDGE
                     QDRQVWISA"
     gene            complement(6093..6473)
                     /locus_tag="LLC22_001483"
     CDS             complement(6093..6473)
                     /locus_tag="LLC22_001483"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5434766.1"
                     /translation="MNLTTIHHIAIIVSDYQKSRDFYVNKLGFEVIRENYRKERDDYK
                     LDLKLGSAELEISGIANAPQRPNYPEACGLRHLAFKVDDIEETIAELQSLGIESEPIR
                     EDTFTGKKMTFFFDPDGLPLELHE"
     gene            6803..7552
                     /locus_tag="LLC22_001484"
     CDS             6803..7552
                     /locus_tag="LLC22_001484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344492.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinamide mononucleotide transporter"
                     /protein_id="HBK5434767.1"
                     /translation="MKSYFQFLAHQLKGWPQQNYYLFFFSLGCQVMTLVNSPITWLSV
                     ITFIGTTLGVLCILSINAAKSVNGILGILSAICFIIVGFSAKNYLSIGEQIAYMITLD
                     IPVLLSKEWNHNMASKIRKFTGKSWFIAIISTFLVYLVSGFLIGRYTDDPRPWVDAIA
                     FSISLTAGIISFLRYNNQYYWWLASGLAQMVLWYISFTHGSASLAMFVNSSVYLLNDV
                     LAFTVSPWYNQKERERMQKMEEEYYNAQQHA"
     gene            complement(7736..9013)
                     /locus_tag="LLC22_001485"
     CDS             complement(7736..9013)
                     /locus_tag="LLC22_001485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434768.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
     gene            complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="LLC22_001486"
     CDS             complement(9092..9736)
                     /gene="pcp"
                     /locus_tag="LLC22_001486"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBK5434769.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            complement(9935..10879)
                     /locus_tag="LLC22_001487"
     CDS             complement(9935..10879)
                     /locus_tag="LLC22_001487"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBK5434770.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            complement(10881..11567)
                     /locus_tag="LLC22_001488"
     CDS             complement(10881..11567)
                     /locus_tag="LLC22_001488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBK5434771.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            12041..12361
                     /locus_tag="LLC22_001489"
     CDS             12041..12361
                     /locus_tag="LLC22_001489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBK5434772.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            12515..13420
                     /locus_tag="LLC22_001490"
     CDS             12515..13420
                     /locus_tag="LLC22_001490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5434773.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            13417..14190
                     /locus_tag="LLC22_001491"
     CDS             13417..14190
                     /locus_tag="LLC22_001491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK5434774.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(14371..15795)
                     /locus_tag="LLC22_001492"
     CDS             complement(14371..15795)
                     /locus_tag="LLC22_001492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5434775.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            16006..16452
                     /gene="nrdI"
                     /locus_tag="LLC22_001493"
     CDS             16006..16452
                     /gene="nrdI"
                     /locus_tag="LLC22_001493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBK5434776.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            complement(16517..18499)
                     /locus_tag="LLC22_001494"
     CDS             complement(16517..18499)
                     /locus_tag="LLC22_001494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5434777.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="LLC22_001495"
     CDS             complement(18513..19409)
                     /gene="murQ"
                     /locus_tag="LLC22_001495"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBK5434778.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            complement(19412..20473)
                     /locus_tag="LLC22_001496"
     CDS             complement(19412..20473)
                     /locus_tag="LLC22_001496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK5434779.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            complement(20684..21250)
                     /locus_tag="LLC22_001497"
     CDS             complement(20684..21250)
                     /locus_tag="LLC22_001497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5434780.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            complement(21278..22780)
                     /gene="eat(A)"
                     /locus_tag="LLC22_001498"
     CDS             complement(21278..22780)
                     /gene="eat(A)"
                     /locus_tag="LLC22_001498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBK5434781.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            complement(23038..24159)
                     /locus_tag="LLC22_001499"
     CDS             complement(23038..24159)
                     /locus_tag="LLC22_001499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBK5434782.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            24285..25226
                     /locus_tag="LLC22_001500"
     CDS             24285..25226
                     /locus_tag="LLC22_001500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBK5434783.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            complement(25376..26272)
                     /locus_tag="LLC22_001501"
     CDS             complement(25376..26272)
                     /locus_tag="LLC22_001501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBK5434784.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            26541..27881
                     /locus_tag="LLC22_001502"
     CDS             26541..27881
                     /locus_tag="LLC22_001502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5434785.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            28099..28542
                     /locus_tag="LLC22_001503"
     CDS             28099..28542
                     /locus_tag="LLC22_001503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBK5434786.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
BASE COUNT         8364 a         6014 c         5221 g         9446 t
ORIGIN      
        1 tattcaaaaa aaatggactg cgacacgact tttgtcacag tcccttcgtg tgtttttctg
       61 ccttctcaaa aggatgacag tttctcactc ttttcctatt tcttctattc aatcaaataa
      121 ctcattttat atacatctaa aaattcacct agatctgttc ttgcccctct aggcatgacc
      181 gcttcgattt ggaagcccat ttttcggtaa aggtgtacgg ctctttcatt acgaacttga
      241 acgtcaagct ccaatcgaaa aagtacaccc atttccttcg cccaactgat gatttcttct
      301 agcataagag tgcctagtcc cattccccaa tattcctgca gaatactgat accgacttct
      361 cccacgtgag acaaacgaaa ttgactgtct gccttgacag atgctgttcc aataatcgtc
      421 ccttcataga ttgcaagcag caataaatta ttattgcttt cgtatatata atccaactct
      481 tcttctaagg tttctggtgg taacaggagt tctgcttcat ccaaaactaa aaattctgtc
      541 tccttattaa cttgtcccat catcaaaaga atgtcttttg catctcctgg cactgcttcc
      601 cgcaagatga tcccaacttc ttcactcatg attttcagcc catttttcta gaattcgctg
      661 tttgaaggtt tcactttgct ccccgtatga gattagtttc acataccgct tttctaaatc
      721 tgtatcactt ttttctaaaa tcagttccaa ataatcctcc ggcagtgctt cttctaatag
      781 atttccccat tcaacaacgg aaagcccatc accttcaaaa tattcatcta accctaaatc
      841 tgctccgcta gctgctaccc gataaatatc catatgatac aacggaatcc gaccttgact
      901 atattctcta ataatcgtgt atgtcggact tttgatcatt tgcgttatcc ctaatccttg
      961 ggcaattcct ttcgtcaacg ttgttttacc cgcacctaga tcaccagtca atatcagatt
     1021 gtcacctggc attgcggaat gaccaattgc ctctgcgaat tgttctgtca ttgttaatcc
     1081 tgatagttcg atcatttttc atcttctccc gctcttcttt ctttttgcca gtatatcgcg
     1141 taatgaagtt tttttaaaga aaaaatgaac tagtcaagaa cagcagctgc tgtttttggc
     1201 tagttcgcgt gtatttgtta atcaatcaat gtttgtgctg ctgtgataat cgataattta
     1261 tatacatctt cttcatttgc tccacgagac aaatcagaaa ccggtttgtt caagccttgt
     1321 agaattggtc cgattgcttc aaagttaccg aaacgctgag caattttata gccgatattt
     1381 cctgactgca attctggaaa tacaaagact gttgcttgac cagctacttc tgaatctggc
     1441 gctttcagtt gtgcaactga aggaacataa gaagcatcaa attgcaattc gccgtcgatc
     1501 atgtattgtg gcgctagttt tttagcgatt ttagttgctt caactacttt gtctacttct
     1561 ggcgatttcg ctgagccttt tgtcgagaag ctcatcattg ctacttttgg ttcgatatcg
     1621 aacaattctg ctgtttttgc agaatctacg gcgatttcag ccaattcttg cgcagttgga
     1681 ttcacgttga tcgcacaatc cgaaaagaca tatttttctt gatctcttcc acgtaccatg
     1741 atcatcgctc cgcttgtccg actgatgcca ggctttgttt tgatgatctg aagtgctggg
     1801 cgaacagtgt cgccagtcga atggatcgct ccagagacca ttccgtctgc aatccccata
     1861 tacgtaagca tcgtaccaaa gtaattcaca tcttttaaaa tcttttctgc ttgttctttg
     1921 gatgcctttc catttctacg ttcaacaaaa gtatccacca tttcatccca cttatcgtaa
     1981 ttatcagggc tgatgatcgt aaagctagat gttttgattc ctctggcatg cgctgcattt
     2041 cttatttctt cttcgttccc tactaaaatg ggttccacaa gttcttctgc tttcaaccgg
     2101 gcagctgcgc ctaaaatacg agcatcagta gcttccggga aaacgatttt gatcccacgg
     2161 cgaacaattt taaatcttaa actatcaaac aattccacaa gatgacctcc agacgttttt
     2221 atatgtatta tcatacacta ttccagaaaa aaagaacagt ttattttatc tgtatcagtc
     2281 aaaaatgctg gaaaaattaa gtttttcaca tacaaagcga actgcactat aacaggaaag
     2341 cgctgtttta ttacactgtt tcaggcagtt gccaatcaat cggttcttct cctaacgcaa
     2401 ggagcgcatc attcgttttc gagaagggtt tggaaccaaa aaagccacga cttgcagata
     2461 acggactggg atgtggagat gttatgatga tatggcgact cttatcgatc attttgattt
     2521 tttcttgtgc cggttttccc cacaagataa acacgattgg tttttcccgt tcatttaatt
     2581 tttcaatgat cgtgtctgtt aatctttccc aacctttccc gcgatgagaa tacgcttgcc
     2641 cttcccgaac ggtaagaacg gtgttgagta aaaggactcc ctgtttagcc catgacacta
     2701 gatttccatg ttgaacaggt gcgattccaa gatcatcata aagctcttta tagatatttc
     2761 ttaacgatgg cgggatcttt acgccaggtt gcacagaaaa agataagcca tgagcttgat
     2821 tttctccatg ataaggatct tgtcctaaaa tcaccacttt aacttcttca taaggagtca
     2881 attccaatgc ttcatagata tgatacatat ctggatggat cttttgggac gcatattctt
     2941 tttttaaaaa ttctcttaga tgcagataat aatcttttga aaattctgag gacaaaactt
     3001 cttgccaact gttatgaatg atttctttca aaaactccac ctcctaataa aaagaataac
     3061 tcacattttc ttcaatcaca agggacaatc ttcaccctca gcacttgatt aatatggtaa
     3121 actaggaaca agaagcagaa aggaacgata atcattatga tcaaattaat tgcatcagat
     3181 atggacggca cattattaga tgcccatatg agtgtttctc ctgaaaatgc cgaggcgata
     3241 cgttttgcaa atgatgccgg tgttgagttc atggtcgcta ctggtcgaaa ctatcaagaa
     3301 gctcgcgcag ctttagatga ggtaggaatc gattgtgcga tgatcacttt gaacggggca
     3361 caggtatttg ataaagaagg aaattcattg tttaccgtgt cgattccaaa taatcaagca
     3421 atctctgttt tagatattct agatgctaac ggtatttact atgaagtagc aaccaacgat
     3481 ggtctttatt ctgaaaatca agcgaaacga attgaaagtt ttgcttccat ggtggctacc
     3541 catttacctc accttacgta taaaatggcg attgccatgg cctcagctaa gctggagtta
     3601 ttgcacatca catacgtgga cagtattcgt gctattttgg aagaaaagaa tctggaagtt
     3661 ttaaaaatta tttgttttca tacagaaggg ccagctgtat taggtccagt tggaaagcag
     3721 atttctcttt taggcgatct agccgttact tcctctggtc aaaacaatat cgaagtgaac
     3781 cataaaaacg ctcaaaaagg aattgctgtt gcccatgtcg ctcacgagcg tgggatttct
     3841 ttagaagaag tcatgacgat tggcgataac ttcaatgatg tcagcatgct gcaagtagca
     3901 ggagtcagtt tcgcaatggg aaatgcagaa atcgaagtaa aagattatgc caaatataca
     3961 acggacacaa accttgaatc tggcgtagga aaagccatat tgcgcgcgat tgcagaagac
     4021 ttgtagtttt atctagaaaa gagggatata gatgtcagaa tttttcattc aggaaaagca
     4081 gcttggacgt gcaactcgga caattgtcaa aaacgaaaaa ggacattccc tgtttttgat
     4141 ggttggtcgc tggggaacaa agggcgatgc attgtctctt tatgccatga atggcgatct
     4201 cgttgctcac atcaagcaga taagcctgac attcggtacg cgttttgagc tgtataaaga
     4261 gttcgaaaag gtgggaacca tgcagaaaat attcaattgg cccggtgact tttattatat
     4321 tcgtagactt cactggacag tccaaggtga tatctataat catcaatatc aaatccatca
     4381 tttcaatcag caaatcatga aaatggataa agcaacactt ttttcaggag attactatgt
     4441 attggatgtc tcaaatgatg aagatgctcc agtttgtatt tgtattgctg cggttttaga
     4501 ttactggctc taccgtaaag acaaaagtcg cgataagcct gtttcttacc gacttaactt
     4561 aagttaaaaa gatgtacctg aaatgcggaa atacgcattt caggtacatc tttttagata
     4621 ttcttttgca tatgatcata aagatgacca ctgatcatcc gctgaccgac aactttgaag
     4681 tcatggcgtt cgtataattt tttagccttt ggattttttt catccacact tagaccgatg
     4741 acggagcgat tagctttctt cgccaattta ggtaatgctt ctaataatcg cgaaccgatg
     4801 ccttgtcctc taaaatcttc tgatacactg atagagtcca aataccattc gttgggaaac
     4861 gtttctttat caatgaacaa acgtgtagac gcatctagct gatatttctc taagataggt
     4921 accagtggct gatcgatgat tgattcttct tcatctgtat aaccgtaagc aactcctgca
     4981 actttaccgt ctatttcttc tacgatacct cgtgaataac tgtaacgata atttggatca
     5041 gtgattgctt cttctaaaat ctctaaagtc ttttgttccc ctgtctgctt caaaaatggc
     5101 agttccatat cttttagaat cactaagatc aatggggcga tttctggagc atcttctttt
     5161 ctcgcaaaac gaatcatagt ttcctctcct tttctccatt ctaacatgca gaaaaagaaa
     5221 tcgcaaaatc gttattttaa aaaatcttca atcttttcag taatgaaata accatgagta
     5281 acgattcttg ccgcttcagt tcggcaataa gggcagacga ctggcatttc tttatcatta
     5341 tgttcgacta cattattgac ttcttcgtat gcaaattttt ttccgcaatt agggcatttc
     5401 attttttcca tgttatctca acttcctttc atctttactc tcttagctta ctcttatatt
     5461 gtaaaaaaga gaagcaatat ccttcttcta tgcagatatc catacctgac ggtcctgttc
     5521 tccatctatt aatcggactt tataataagg acgttcatct ttgactagaa gtgtccactc
     5581 tttcactttt gcttttttcc cgtagtagct gactgcttcc ttcatcgctg cttgcggttg
     5641 tttgaactct tccgtttttt ctatatcaaa aagatgttct gcggcctttt ccgtgtcatt
     5701 tcgtacggtt gttttcccag tggatggatt gactgctatg acttgtcctt cacaaaaaaa
     5761 ctggtattca tatgttgcat tcgtaggatt ctccaaatct ttttcaactg caaaatgaat
     5821 agcagatatg ttatgttctt ttgtttcgtt ttttacgatt gctgctgctt ttttcaatga
     5881 gatccgatat tcctggtcac taatatcatc catgtgaaaa gcggcattga gcagtcccgt
     5941 cataccggta atccctatta cgatgagggc agcaacacca aacatcattt ttttcattct
     6001 tcattctcct gtttcttttt tttaaagaat atcaagaaat gaacgaatga aaaatcgaat
     6061 gaaacgaaaa aaaagtgaca attttgttat ctttattcgt gcagttctaa tggcaatccg
     6121 tctggatcaa agaaaaacgt catttttttt cctgtaaagg tatcttctct aatcggttct
     6181 gattcgatcc ctaaggactg caattctgca attgtttctt caatatcgtc tactttgaaa
     6241 gcaagatgac gcaagccaca agcttctgga tagtttggtc gttgtggcgc attagcaatt
     6301 ccagaaatct ccaattcagc acttcctagt ttcagatcta atttatagtc atctcgttct
     6361 ttgcggtaat tttctctgat tacttcaaat cctaatttat taacataaaa atcacgtgat
     6421 ttctgataat ctgaaacaat gatggctata tgatggatcg ttgtaaggtt catatgagca
     6481 ctcctattct tcgtttaagc tcggatctat attaatctcc agttccattg taaatgtgtc
     6541 agattgaaaa aaatagctgt ttttcctttt tataagaaaa aaggcaaaaa aaacagaaag
     6601 taggtcctcc aagacactct tcctgttccc aatataataa atgaaagtaa gaaattatat
     6661 tttcaagaaa acaaacagaa aattatcata acacaaatta tttataattg aaagactagt
     6721 tttttttcaa gaaaagcata caatagattg tgttagtaaa tacagaacac actacattta
     6781 gtgtcttaag gagtcctcat acatgaagtc atattttcag tttttagctc atcagctaaa
     6841 aggctggccg caacaaaatt attatctttt ctttttcagt cttggctgcc aggtcatgac
     6901 tcttgtcaat agtcccatca cttggctgtc cgttattaca tttatcggta ccacgcttgg
     6961 tgtattgtgt attttatcca tcaatgcggc aaaatcagtc aacggtattt taggtatttt
     7021 gtctgcgatt tgttttatta tcgttgggtt ttcagcaaag aactatttaa gtatcggtga
     7081 acagattgct tatatgatca cattggatat ccccgtattg ttaagtaaag aatggaatca
     7141 taatatggct tcaaaaatcc gaaaattcac tggaaaaagc tggtttatcg caatcatcag
     7201 tactttcctt gtctatcttg tttcaggatt cctgattggt cgttatacag atgatcctcg
     7261 gccgtgggta gatgccattg ctttttctat tagcttgact gctggtatca tcagtttctt
     7321 gcgttacaac aaccaatatt actggtggtt agcttcaggg cttgctcaaa tggtcctttg
     7381 gtatatttca tttacgcatg gatctgcaag tttggcgatg ttcgtgaaca gctctgttta
     7441 cttgctgaat gatgtccttg catttaccgt ttcaccttgg tataaccaaa aagaacgtga
     7501 acgtatgcaa aaaatggaag aagaatacta caacgcacaa caacacgcat aaaaaaactg
     7561 agcgtgggac aaaagtaaag aacacttttg tctcacgctc taaacacgta taaacggcgg
     7621 aatcagaagc aactccttcg gaaataagct gaaattcaca aaaatttgaa aagcaatttt
     7681 cgtgaatttc ttcttatttc ttggagttaa acgcttctgt cccagcctct attttttata
     7741 gtaattcctt cagatacttt cttgcctcat cattgaaacg cagtgattct tctaacttct
     7801 gataatattc caacgcttgt ttctgagctt cagtaaaacg ataatgtttt cctttccatt
     7861 tgtcgattgt ctcttgcaca tttccagatt ggatatcttt cactactagt tgccattttt
     7921 cttttgagac tgtacggtct ttcttatcag cagattgtat agcttctcgt tctttacgca
     7981 atacttttaa aaaaccattt ctgactatcc gaggaatgct gtcgaagaac ccttctgtaa
     8041 aaccatagtg acaatattgc ttccaaataa atagatagat ttttggttgg atgaatcgtt
     8101 ggtttttcgc aaaatattcc atctgagcag tgacttctgg tgttcgttga cgttttgtct
     8161 ttctcaacac ggaaataaat gtttcaaaat aagcattagg atgtactggc acttcttcat
     8221 atacgatgga ttgccaatct ttacgtaaaa atgcgcgata gttgatcaag aattcttcta
     8281 catcctttac taattcttct gcaaagtcgt caaatagttc tttttttatc tgtcgctttt
     8341 ttgactgccc attgatgtgt tcacttattt tcttgatttc attttccaat gcttgataat
     8401 ccgctatgta aatcggcatt tctacttggc gaaattctgc gagccgctga gctaatttta
     8461 tatccggtaa atatggctgt ttcatccgac gattttggta caagacaaaa cagtattttt
     8521 gccatagtcc ttcaggaaaa tcgatattct tctgcttaag ccataataat tcgtctaagg
     8581 ccagatcaac ttttgtcatt ccctgatgga tcgaagctgc cactgtcgga gagacatgca
     8641 ggtgatcggc aaagtggttg atgcctagtt ttaggatctt tccggttttt ggcgatttaa
     8701 cgatgtattg cacttttaat tctctaccac actcacaata caatttttgc tggcttcgtt
     8761 ttgttcgaaa aaacggattg atcttgaagt cagaaaacac ccaatctgtt gcagctaaat
     8821 aatgttcttc cataaaacga gagctgatta gatatcggcg gtgcttatcg actagttccc
     8881 gctgtttttt cgttaatttt gcatagatct cccaacgttg actgcttgtg tattgtttag
     8941 aaattttgat gggatagctt ttgctgattt cttttggaaa ccattcttca aagacggatt
     9001 gccattcttc cacggctgtt tctttccttt ctaattacaa aaagctggct actaacataa
     9061 cgttagcaac cagccagtgt ttcttgctaa attagtgagt tgttccggca tttccggaaa
     9121 tatcttcttt attttctact gctgcttcaa ctgcataagt caaagaagaa gcaatgtctt
     9181 ctaaagacat agaaggcgta cccactggac gatcgatcac ttgatcgggt gagaatggca
     9241 cgtggatgaa cccacctcga attgccggga attgtgtttc gatcaaatga agcaaacgat
     9301 acatgatatc attgcagaca aatgttcctg ctgtataaga gatgtacgct ggtagaccat
     9361 gatcttgtac attttttgtc attgctttga ttggcaatga ggtaaagtaa gcggctggac
     9421 cgttttcttc taaagccgta tcgaatggct gatttccttc attatcaggg attcttgctt
     9481 ctgctagatt gattgcgaca cgttcgaacg agactgctga ccgcccacct gcttgtccga
     9541 cacagatcac gacatctggt tggtgctgtt ggatggcttc tttgactact tgactgcttt
     9601 tttcgaatac ggtcggtact tccactttga tgatttcagc accgctgatt tcatctggca
     9661 ttttttttac tgcttcatag gctggattca ctttgtcccc accaaatgga tcaaaacctg
     9721 ttactagtac tttcatctgt tgttcctccg tccgattgat ttaacatatg gttatctttt
     9781 atcataccat tttccttgaa cagcgtaaat aaaggaaaca atagtttaaa taacataaca
     9841 gatcaaactt aatatattct tataaaaaaa tagtgttcca ctacaatgtt agaagaggtt
     9901 gcgacaatta ttctgtcaca acccctctct tctattattt aaatagaatc atataagcaa
     9961 tttggaaaac tagcataaat aacgcaataa acaactggtt tttgatcact ccgtatttgt
    10021 ctttcatctc cagcatcgct acaggcacga tattgaagtt agcagccatc ggtgtcagca
    10081 gggtcccaca aaaaccgcaa gtcaatgcaa ccattcctat taacgctgga ttcgctccat
    10141 gactaaatac gaatggtgca ccgatcccaa ccgtcatcac ggtgatggcc gcaaatgcat
    10201 tccccatgat taccgtaaat atcaccatgc caagagcgta aatgatgatg ccgatgttca
    10261 catttccttc tggaacgatc gtacctactg cattggaaat cactgtccca actccagcgc
    10321 ttgtaaatac cgcacctaga gaagctaaaa gcattggcaa catgcttaac ggccctactg
    10381 tgcccagcat atctgctgca tcatctaaaa atgtacttgg tcgattatct cgagaaaaga
    10441 acatcaagat tagcatggct gcaaaaacac cgacgcccac gccgactaaa gcacctaaat
    10501 tggtaaatag agcaaacaag atcgcaaaga caccgatact caaagctgga ataaaaattt
    10561 tcattcctag tttgtctgac attttttcca tatattcttt tgatggaagc cggctttctc
    10621 ctttgctgac tttcttagca attgctggta tggtcatcgc aaagatcaag ccaccgttca
    10681 cgattgccgg aagccatctt cctcctgcaa taactacccc taagaccgtc cagaaaaagg
    10741 ctgacccata acgatgagga ttggttttat ctgttaaatt tcttactcca gtgtaaatca
    10801 atacgagtcc catcacgata taaaggatct ccagtaattt atcgcctaat aaaatatcag
    10861 gatttgtaaa aaagtccatc ttattgcccc tttcctggat aatatttctt cgctaatttc
    10921 ttttctttaa gatagaagta gacacttgcc acaactaaag ccgtgatagc cactggaact
    10981 tccactaaag caagctgtcc caatgttacg tcatatccta gatctttcag tgttgattgg
    11041 actagcaacg cccctgctcc tccgatgaat agtacttggc caaagaacca gcagacattt
    11101 tccatagctg aagccatacc ttttagttct tcttcatgct taggatggac ttctaaccct
    11161 tttgattcga tggtccccaa tgccatcggt aaaatgattg gacgaacaaa tccagcaact
    11221 ccaccaaaac tcacgttaaa agccgcaaag atcattcgaa agatcccata aatatctaca
    11281 atcataccag cagatacttt cttgaatcgc ttgatcaagg aagccgctga ttctttcaga
    11341 ccatttcttt caagcgttcc tgttgccaac ataatgatga taaaaatcgc catcccgcga
    11401 ttgtttacaa aacttgtacc taaaagttct aacattcctt gaatgccaag accgccagtc
    11461 aaagctgtaa caactaaagc aaccattacg atcaatatcg agtctaattt aaatgcaaac
    11521 ccgagaataa caatcaagac gcctaaaagg ctaagataat tttccatata ttttcctcca
    11581 taaaatgaca atattttttt aattataaag caaaacacat aaaaaatata gttgttttct
    11641 cacgaaatag acactatttt taaatatttt tcgttatttt tttatcacaa aaattatctt
    11701 acttattgta aggtaaagct ttttttaatt tattgcccga taatatatag aaataaggtc
    11761 tagttactgt tttttttaaa tgattaataa ataacaactt ctttctatga aattgcaaag
    11821 cattcatctt cttttccgct aacgatatat ccgtcagtgc ttggtacact ttactaaaaa
    11881 gtatgagatt gccgatatct ggataggtgt gctatactac agaaaaagat atacaatctg
    11941 ccaccgggta ggataaagag gatgatcatt ccattaggtc tttgaaggga tgattttcct
    12001 ctttttgtgt atttttttat agttaaggag gaatgtaagt atggcatgga tggaattaat
    12061 catagcagga attttggaag tattctggtc aacgatgatg aaatggagtg atggtttttc
    12121 taaaatcaat tattcttttt acacagtgat tggcatgatt gctagttttt actttttgtc
    12181 aaaggcaatc aaaagtttgc cgatgagtct ctcttatcct atctggacag ggattggcgc
    12241 agttggttcg gtcataattg gtgtggtctt gtttcatgat aagctgaatc tttccacttg
    12301 gttctttgtg gggatgctac tcatcagtat cattggcatc aagattacta gcggccacta
    12361 gacacttgga ataagtactg atcagaaaaa ataagccttt ttatttaata ttcaattttt
    12421 ttatgaaaaa ataagaaata agtccaatga cctagcgact tctccactca tcaggtgtat
    12481 gcttgtacta tctatagaaa aggagtgaat atttttgaaa agtctttcgg tccaagaatt
    12541 atccaagaac tttggtcaca aacaagccct cagcgatgtc agttttagct tatcccctgg
    12601 caaaatcgtt ggattagtag gtcctaatgg cgctggaaaa acaacgatca tgaaagctat
    12661 tttaggactg atccattact cagatggaac aatctgtatt ggtgaaaatg agatttctcc
    12721 ctctagtcat aaagggttgg aacaagtagg agcattgatc gaatacccgg gtatctatcc
    12781 attcttaaca ggctatgatc atctgaagtt attctctgaa accaacgatg tatctgctat
    12841 cgacactatc gtgaatcagc tcaagatgga aaagtacatt cacaaaaaag cgaaatccta
    12901 ctcgttggga atgaaacaaa aattgggaat tgctcttgcc ttactgaacc atccgtctat
    12961 cgttatttta gatgagccga tgaacggttt ggatccacaa gcaacaagag atgtgcgaaa
    13021 aatcattacc gacttggcta ctcagggcac ctctttcttg atctccagtc acttactcag
    13081 cgagcttgaa aaaatggtcg atgagctgat cctgatcaat caaggaaaga tcatcaaaca
    13141 atgtacaatg gctgaattga accaaacagc gcaagatttc atcgttatct ctacaacaaa
    13201 tgatctagct gctcgaacga tcttgacaga agctggatat actttggaag atcctgataa
    13261 aatcaagctt ttaaaagaaa acgaagaatt attaggaacc gtgatccagc tattgtctgc
    13321 acaaaatatc catgtgacag acgtccagca tctgacgaat gatttggaat cttctctatt
    13381 ggaaattctg gattcagtaa agggggaaga agaaaaatga cattgcttgt aaaacaagaa
    13441 ttatttaaat tgatcaagaa aaagtcaact gctgttttat ctgttctatt agttgttttg
    13501 ctcataggaa cagcacttct agccaaaaaa tacacgacga tcattgatcc agttgaaatg
    13561 actgctcagc tttttagtgc cacatcttgg attgtcttta tcatgattgc agctgcaagc
    13621 acgatcattt cgatggaagc acaatatggt acattgaaaa atctccttta tcgaaagtat
    13681 tctcgaggag aaatattagt aagcaaatgg atcacattag ttatttattc tgtttattta
    13741 taccttttag ctattattgt cactgtgttg atgaaactga ttcttttccc ttcgatttcc
    13801 ttcacggaga aggtttctac tggtcaaaca ctgatccaaa gcttgttcac ttatactttg
    13861 ggtagttata tcggtttatg gctgatttta agtttagtgt tgatgattgc ttgctttatc
    13921 aatagttccg gcgcatccat ctcagcagga atcgtctttt attttgcttc gtcaatcata
    13981 tctggtatcc ttattgcact catccaaaaa tgggagtgga tcaaatggaa tccgatcagt
    14041 atgttgaatc tgcaaaacca aattggaaac gaagagatca tgaagcaatt gactcatctt
    14101 tctactaatc aaatgctatt cggtaattta gcttacatcg ttttgttctt agcattagga
    14161 tatctcgtat ttaagcgaaa aaatgtatga tgactcatca aaaaagaggc tgtgaaagag
    14221 acgttcagcc ttattgccga ttggctgtct cttaaacacc gtttattctg aaaaaggagc
    14281 tgtgacaaca tttgtgtcac agctcctttc ctagtatgtt tttgaataaa cgacaggctc
    14341 acaacctctc tttatacttc ttttatactt ctatacgtga agcatcccag tggcaaataa
    14401 aaccattgca atcactccga ccatcgtcac acctataagt aaaatcttat ctaagtggat
    14461 atgttgtaca ggctcgtttt gctccttacg tgctttgagg taaaaataaa tgcctggcaa
    14521 gaaaagaaca agaacaagca ttacttcatt aaaggctacg actagcatag cccatacttg
    14581 aaaggcactt gctaaaagcc ctactaaaaa ttggacccat tctttccgct gataagaaag
    14641 tttcatttgg tacaatccta agaaaagcca cgtgaagaaa atagctgctg taccaagtgt
    14701 gtaagcaaag ttataagcac tgtcagtgaa taataatgaa agtaaaaaga cattcgtaca
    14761 taacgtcgtc aatacgatag cataagttgg tgccccattt ttgttgagtt ttccccatgc
    14821 tttaggcaaa agtccgtctt cagccatgtt tcccattgtt tcaatcggta agatcgtcca
    14881 tgagagccaa acaccaacta aagaaatgat caaaccgccg ttgatcacga ctgctcccca
    14941 tttaccaacc atcatttcaa acacatagcc catagcaggc tgcgccttga tcgtttgcag
    15001 ctgattcatc gtcattgtcc catatggaag catggaaacc aagacgtaaa taataatcaa
    15061 gccgaatatc cctagaatcg ttgctttccc aacatctgat tgtttttttg ctcgtgaacc
    15121 tacgacagag gctccttcaa taccaacaaa tacccaaagc atcaccatga tgcaactcaa
    15181 tacttgactg gaaaacggga tcggctgtcc attcgcattc aatataatgt cgctagaaaa
    15241 gttatcaatg aattgttgga tcgaaaacgt gctgatagct actacaataa ataaaaataa
    15301 tggcactaat ttacagaatg tgacgatagc attgacgaaa ctagcatttt cgactccccg
    15361 attcactagc catgcatatc cccataaaaa gactgtactc atcacgatcg atgccagatt
    15421 ttgcccacct tcaaatactg ggaagaaata tcctaatgcg ctcatcaaca atgttgcaaa
    15481 agctacgttg cctaaccagc atgtgagcca gtaaccccaa ccgctgataa aaccagcgaa
    15541 acggccaaaa ccttcttctg cgtaactaaa gatcccgcct tttaaatctg gacgtttttt
    15601 attgatatta ttgatcgaca aggagagcat caacattgct gttcctacga gtacccaact
    15661 gaaaatagct gggccgccag ccgatccgga gatgtccgtc ataataccaa atacgccacc
    15721 tccaatcgct gaaccaatta ctaaggcagc aagtggaatt aaaccaattc cttttttctg
    15781 ttgctctgta tccatgtaag catcctccaa aataaaaccg cttttatcaa aaagtataac
    15841 aaaccttttt tatttttact taattaataa aaactttaat agaaatataa ttctaccggc
    15901 ttttttctca ttatacaagc aaagcgccta gtccctttcc aaattacacc accaaaaaac
    15961 ttaaaaaaga tgctatacta aaaggaaaga attggaggat gatccatgaa cattttatat
    16021 atatcgattt caggaaatac gcgtgccttt gccaaacatc tagcagaata tgctgaaaaa
    16081 atgcatgcag aagatcctgt caatcctgaa gttactttaa aagaaatcca tgaaaatagt
    16141 gattttacga aagaaacaga accatttttt actttcgttc ctacttattt agacggcgga
    16201 aatggtttag ataacggtga tacagaaatc ttgaccgaaa cgatgcgtga atatctggaa
    16261 catgaagaca atcataaact ttgtcttggt gtagtcggta gcggaaataa aaacttcaat
    16321 aatcagtatt gtctaacagc caaacaatat gcacaaacat ttggctttcc tttcttggca
    16381 gattatgaat tacggggaac accatctgat gtgacacgaa tttatcagat tttagcagaa
    16441 aacaataaat aataaaaaag aagaagctga aaaatagatt tcagtttctt ctttcgtttc
    16501 tattgtttct atcatattaa gctttgacat ccatcacagg tgcttttgct tttgctttac
    16561 ctgttttttc caagacaaag ttttttacac gatccatatt ggttaccaag acgatcatgg
    16621 atgtttcttt gcctgctgct ttgatcgctt ctaagtcagc ttctgctaca agcgtatcag
    16681 gtgtcacttg ctgcccttct gttactttca catcaaatgg cgtaccgcct aagtcaactg
    16741 tgttgattcc catatgaagc aagatttcta aaccatttgg cgttgtgatc ccaatagcgt
    16801 gtttcgttgg gaagacagag ctgactaccc cagtaactgg agaatagata tgtccgtttt
    16861 ctggttctac aaagtagcct tcacccatca tcttttgtgc aaaaactgga tcacttgctt
    16921 tatctaaaga aacaactgtt ccgtcagcaa ctgatgagag gatagtcaca ctttcagctg
    16981 aagtttgagg tactactttt tcaggcactt catttactgt ggctgtttca gtcgctaatt
    17041 cttctttttc taaacggtct ttaggaatac cgaagaagaa tgtagcaacg aagccaccag
    17101 cataagctgc caataatcca aggatgtagc ctaaccattt accgtcagag atcaatggga
    17161 tcaaagcggc tcctgaaggt ccaatagcga tagccccgac atttccgatc attccgatca
    17221 ctgccccgcc gatacctcca ccgatacaag cagtaataaa tgggcgtcct agaggtaatg
    17281 ttactccgta aatcaatggt tcgccgattc ctaggatccc gactggtaaa gctcctttga
    17341 tcatttctgt taattcttta tcttttttgc agcgaatcca taatgccaat gctgcaccca
    17401 cttgtcctgc accagccatc gcaagaattg gaagcaatag cgtacgacca gtttcatcaa
    17461 tcatttgcac atggattgga gtcaaaattt gatgcagtcc gaacataacc atcggcaaga
    17521 ataatgtgcc tagaacgaag ccggcaaatg ctccaccaac gccaagtacc cagttgatcc
    17581 caccgaccat gccatcagaa atgaaacctg ctaaaggcat gatgaagaaa atttcaatca
    17641 gaccgatggc aatcaacgaa agagttggtg taacgatgat atctaccgca tcaggtacta
    17701 ctttatgcag ttttttctca acgattgaca atagccaaac agcgaagatg acacctagga
    17761 tcccaccttg tccagctgca agagcttcac cagtaaataa gtttttcagt ggtgcttccg
    17821 gattcatccc tgtcagcatc acaacggccc cgataactcc accaagagtt ggtgttgcac
    17881 caaaaacttg tgcagcattg atacctgtat agataactag gtagctaaac atcccgtttt
    17941 tcaagatgtt catcacatcg atatattgtt gccatgttgc tgcatcaagt gttccggctg
    18001 tgactaagtt tgctaaaact gcggcaatcc ctgccacgat cccagtaccg acaaatgcag
    18061 gaatcattgg cacaaagata ttagaaatgt cttttaatac cgatttgatt ttagatggtt
    18121 tttgtttcga tttttgtgcc gctttcattt cttgtgcccg ttcgtttaca cggtcttttc
    18181 cagatgctga tgaatttgct gtagctgtac ttacagaaga aagtttttct cctaatttca
    18241 cgcctgccaa atcaaccatt tgctgtgcta ctttgttcac tttcccaggt ccgatgatga
    18301 cttgaagctg ttcatcttct actacaccaa gcactcctgg aatcgctttt aattcagaga
    18361 catttacaag atcatcattg atgatcttca tacgcacacg agtcatgcag tggacaatgc
    18421 tttctacatt gcccatgccg cctgcccctt tataaatttg ttttgccagt tcttccaaag
    18481 tcagttcgtt ttttgccatg gtcttttccc cctcataagg tcccttttac aaatccgttt
    18541 gcttcagcta attttgcttg agcttcctct ttatcactat ttgtcaaaat catgacgata
    18601 gccagcttaa cattttgatc tgcttcttca aagtactttt cagctgtttc gtaatcagct
    18661 tctgtcgctt gcatgatgat tcgttttgag cgttcgatta gtttttcatt tgttggtttg
    18721 acatcgacca tcaagttatt gaatacttta cctataccaa tcatactgat agtagaaatc
    18781 atattcaaga taagtttttg tgctgttcct gacttcaatc gagtagagcc tgtcaaaaat
    18841 tctggacctg catcgacttc gattgggaaa tccgcgtgtt tactgatttc ggcttgttta
    18901 ttgcaagaaa tcgttcctgt gacagcaccg atcgattttg cgtaatctaa tccaccgatc
    18961 acatatggtg tacgaccgct agctgcgata ccaataacta tatcattttt tgtcaaattc
    19021 agcttgatta gatcttcttg ccctagctca taagaatctt cggccccttc gacagctaca
    19081 gtcattgctt cttctccacc agcaattaga cctatgacca tttccggttc tacaccgaat
    19141 gtcggtacgc attcagcagc atctaacaca cctagtcttc cacttgttcc ggctcccata
    19201 taaatcagac gtccaccttt tttaaaggac tcaatcgtgt tagcaatcac tggttcgata
    19261 cttgtcagtt ctttttcaac cgcagcggcc actttctgat cttctttgtt cattagttga
    19321 acggcttgag aaatactcat ctcatctaat ccaaaagttt cttggtttct gcgttccgtt
    19381 gttaggttct ctaaattgat tttgctcatt tttatcttcc ttcttttctt ataaattgat
    19441 agttcatacc agctttgatt tggttgatca atggtagctc ttctttgata actttagcta
    19501 ctacattcac tttttcatcc gctggcaaat catatttggt taattggatc tcacccatat
    19561 agcgcaaata cttttcgtta tctaaagtaa tagacccttt catacgcgta gctgtatttc
    19621 ttgctgggat aggcggaatc tctcgaaaac gtgcatctac gcttcgtatg acatctcttg
    19681 catcgtcttg ccgattcgta tgcttcccta atatatattc gtaaaattct tcatctacag
    19741 gttccgtatg gagcaagact gtctgttctt tttggaaaga agcaaattgc tcctgaacgt
    19801 tttctgacag acctgcatct ccgatgtaaa caatatccgt gttacttgct aatagatcta
    19861 gagcgcctgc aagaggatgg atccctcgat gttcttccaa agttggcaat ccttgatata
    19921 gtgggcctct caactctgta tctcctggta caaaaccttg gacaaggaga ccttgaattt
    19981 tgagccattg attttttttc tgataccatt ctttgtccag ccctgtttcg ggacgtggat
    20041 aataattatg ccaagcttca atctgtgaga aatcagcttc tgcttctttc aattcatcga
    20101 tatctttagg cgtgatcgtg ctagcattca aactgatttt caattgatgt gaccagtcgg
    20161 caatctgctg attggaaata tgataatcca ttcttaaacc tgttacacca attgctttca
    20221 aaggcgttag atcttctaat gaaaaacccg ctcgttccaa tgcctctcct gaaatatcga
    20281 ccatcaattc tagtttattc tttttcgctt cgcttcctag ttcgatcaat cgcttttgat
    20341 atgccgaaac atcatcttct ggtatatgca tggaagtgaa aataccgaca aagccattgg
    20401 atgccatttg gcggatatac tgtttcttct cttctgacaa agaatcgttc ataaatattg
    20461 aaaagccaaa catattatcc ctctttttct gtatccgtct tcatttctat gactagagta
    20521 tatatctaaa gaaacaaaat ttcaatactt ttattaaaat aattaaattt catttctaaa
    20581 ggttgagttt atattatcaa aagaattgtc ataacctaaa aaaggcactg ctaagcaaaa
    20641 gcagtgcctt gaaatatttt atttaaataa cacaaaaaca taattactca taagaaacca
    20701 attctgtatt atctaccatg aatgtaaaga acccctcatt aggcatcgga tgaaaataag
    20761 cattgatcac tcttatcaag gcattatggc aaactaacag atagacattt tcttcgtctt
    20821 cgatgcattc tttcaataaa ggaacgatcc gtgcatacac atctaagact gactccccat
    20881 ttgggaatcg tacagcgaac gctaaacgtg ctttttgaaa gttctcatct ttgcttggca
    20941 gtccatcata atccccaaaa tccatttcta ccaatcgttc atcaacggtc agcggcaagc
    21001 tgagacgatc agcaactgct tgtgctgtat ctcttgctcg ttgaagaggg gaatggatga
    21061 ttttcgtgat tggaacaggc aaatctacta ccttttctgc tagtttctgt gcctgcatct
    21121 gtcctttttc agtcagcggc acatctgccc gtccgcaaac taatccttgt gcgttccaag
    21181 ttgtttctcc gtgtctcgtt acataaagca tgtgattctc tccttcgttg gcaaagttcc
    21241 ccttaaccat accttgttgt tcttgagatt acaagggtta gattctctca agagaaataa
    21301 tctcagtaga tactttatcc aggaaggttt gatcatgttc cactagtaac atggcaggtt
    21361 tcacgttcaa gatcagttgt tctaattgtt cttgattgaa gacatccaaa taattcaatg
    21421 gttcatccca tgtatatagt tcagctggct gtgataaaga tttagccaat tccacttttt
    21481 tccgttggcc catactcatc tgctcgatct tgttatgaaa aacatctctt tccatcccaa
    21541 gctttcggag gttgttcaaa aatgcttggt agtctacttg gtttttctct gcaaattccg
    21601 ccaacgttcc tcgattgtct tcataatttt ggcttgcata actaatgctc agatgttttg
    21661 gctggtattt ttctcctata accttgccgt tgaatgcccc cagaagataa tggataatgg
    21721 atgactttcc tgcaccgtta ggacctgaaa tcgccacccg ctgatgaggc tcgattgtaa
    21781 aatgaattgg ctcgaataac agattttcat accctaattg aagatcttct acgcttaaaa
    21841 gtcgcttatg gtgagacgct tggctattca tcgtcaaaga atcgatatat tcgatatctt
    21901 ttaatagttt ttctttctcg ctgatctggg tctccatccg attcacgatt gctttggatc
    21961 gtttcatcgt ccgtgcagca tcagcaccca ctgctccttt attcactcgt ctagattcag
    22021 tatcgatgaa tccgacttgt ttctttgttt tatctccttc tcgggaacga gaccattcgg
    22081 ctttttcagc tgctgttttc tttagcctac tgacttcttt tttcaatttt tcattttgag
    22141 ccatttcaaa ttcatcacga agttttttct gttcttcata gatagagaaa ttcccttgat
    22201 aaagttccag ttgacttttt tcgattgcta aaacatggtc cactacttca tcgataaatc
    22261 cccggtcatg gctgaccacg atgaagcctt gttttttctt tttcaaataa gccgctactt
    22321 gttttctacc agagatatcc aaatgattcg ttggttcatc gattaacggg aaatgagtgt
    22381 catccacaaa taaaagtgcc agtaggactt ttgtcttctc tccccccgat agtgtgctga
    22441 attctctcca taagatttca ggatctgttt gcatcaattg gagctctctt tcgatttccc
    22501 atatctcaaa atccgtaata tcatttaaca cgtaataggt taaacgttct ttatcttttg
    22561 tctgttgcgg gaaataggca aattcttgct gatggattac ttgcccttga taaggtagtt
    22621 tgttttgtag aatattcagt aaagttgtct ttcctcgacc gtttcgtccg ataagtccta
    22681 gtttccattg tgtgtcaaaa tttagatttg cttgttcaaa taataatgtg ccttggctgt
    22741 cgtagccgaa tgtcagattt tttatttcga ttttagacat tttccatcac ctcgtaaaaa
    22801 aagaccagtc ctattttcag aactggctaa agaggatgca agggttggat acacacaaaa
    22861 agacccatac atcgaaaaaa ccaagccaat cccgaaaatc tgcacactgc ttccttgtct
    22921 ccacaaggta cagtctgaat gcagctttca tcaatcgact taatttttca atgcacggat
    22981 ccctcacttt gtcctatatt tgaaattacg atagcataaa gaaaatgatt ttgtcaacta
    23041 cttcgggagg atggtgaaaa atctgctaag tgtctgtcct aagatttttg ttttttctaa
    23101 tgtttgcctg tgttccattg cttcttctaa acctattgga cccaaatgaa tacttaagac
    23161 aattgggaga aaatcagaaa gtccttctag ctcttggtct ctacttccgc aaatagcgat
    23221 tattggtttt cgatattttt ttgcaagcac tgctacaccg tatggaactt ttccgtggat
    23281 cgtttgctga tcgatccgcc cttctcctgt aatgatgaca tctgcttgtt cgatcttttt
    23341 ttccaatcca gtgatttggc tgactaaatc gaaaccagaa accatcttcg ctcccaacaa
    23401 aaaaagggct ccaccaatac cgcctgctgc tccacttcct ggaatatcat ctaaatccac
    23461 ctcccagaaa tcttttattt gctgagcaat ctttcctgct tgtttatcta agaaagctag
    23521 cgtcgtatct attcctcctt tttgtcttcc aaattgccaa gcagctcctt gttgacctgt
    23581 atatggattg gtaacatctg cagcgataat caattttact ttagaaacaa gaacgtttct
    23641 tcgatcaaaa tgaagttttt tagtagataa taaaggattt ccttctgtgt acccttctaa
    23701 agaagcaccc aaggattgga gtaatcctag accaccatcg ctacacccgc ttcctcctaa
    23761 agtgacaata atttgttcta cttcttgaag cagtgcatct ttaataagtt ctcctaaggc
    23821 ataactggaa gcaagtcgga tagtttgatc cgttggttta tcaagtagat ctaaccccaa
    23881 tgcttgtgca gattcgatga ctgcggtgtt ttttccttgc caagttgtca ataaatagct
    23941 gatttttcgc tgacggaata agagatccat cccatcaatg gtacgccatg ttcccctgag
    24001 cgcgtaatag attgcttctg cagtattttc tccgccatct gcaatcggca cattgatttt
    24061 tcttccttta cgatcttccc agccatttag aactgcctga tttagttcaa atgaagaagc
    24121 acttccttta aatgaatcaa ttgccgccaa aatatccatc tgtatccctc actttcttct
    24181 taagtaagac actttttttc atttttttca aacaaaacaa tgctattttc ttccattttt
    24241 ctatatacta aaagggaact cattgaataa aggagagaaa aaacatgaaa atcgcaatag
    24301 ctggggccgg agcaatgggc agccgaatcg gattgatgct acatcaaagc ggaaatgagg
    24361 tcctcttgat cgatcgttgg cctgctcaca ttgaagccat tcgtacaaat gggttgattg
    24421 ctgactttaa cggtaaagaa gtggtcgcaa aactgccaat ctattcacca gaagaaatca
    24481 tcgaaagcaa cgaacacgtg gacttgatcg tagcattaac aaaagccaat caattagatg
    24541 atatgttttg ttcgatccaa tccattatta ctgacaatac ttatgttttg tgtttactaa
    24601 atggattagg tcatgaagat gtactggaaa aatatgtgcc aaagaaaaat atcttatttg
    24661 ggatcacgat gtggacagct ggtctagctg gtcccggaaa agtcacattg ttaggtgatg
    24721 gagaaatcga actagagaac ttggaaccag aaggcgaagc atttacaaaa aaagttgtag
    24781 aagtctttca agaagcaaat ttaaatccga tctatagcca taacgttcgt tattccattt
    24841 ggcgaaaagc ttgtgtaaat ggaacattga atggtttatg cacgattttg gattgtaata
    24901 ttgctgaact aggcgcgcaa aaagcggcag agagcatggt tcgaacaatc gtatctgaat
    24961 ttgcttctat cgcagcaaaa gaaggaatca tactagatca agaagaagtg taccaacata
    25021 ttgcttctac ttatgatcct gacaacatcg ggttgcatta cccatctatg taccaagacc
    25081 tgatcaaaaa ccatcgtttg actgaaatcg actacatcaa tggtgccatt tggcgaaaag
    25141 gacaaaaata tgatattgct acaccatatt gtgccttttt gacccaatta gtccatgcaa
    25201 aagaaggaat ccttggcgca gaataaaagg ctctctgatg agaatcagct gaatcagcag
    25261 ctggttctct ttttttaagc ccaataaaag atcaaaaaga aaacacaact ctcatgatgc
    25321 cataagaatt gtgcttgttt gtttcagtac ataatctctt caaaatgtag gttttttatt
    25381 tgttttcaac agaggagagg tcatattcgt attgctcata aatagtggaa tcgttagtga
    25441 taaatcgttt tgcccaattt tctgcatcat aaaattccaa tagctctgat aggattggct
    25501 taaatggtgt atgcagaaat tccggtaatt catctaaatc acgttctcga agcaaaaaaa
    25561 tattttcagg acgataaaaa tgataatgag caatcgcttg attatccgtc actagtttct
    25621 tttgaaaata catggattca aatgtccgca aagtcactcc ttgctgaccc tcccgcaaca
    25681 gttccagaat cccgcgcgat tcccctgttt ttttcaggta ctcttcataa gtaagatatc
    25741 caggttgttc attccctcga tgtggaagaa tgaaatagtt ggtcgtaaca tctcttttta
    25801 taaattcctg cttatagctt tctgctcgtt cttttctccc attattcgtt gcaccaaaaa
    25861 atagatccgt ctttggttcg ctagaagaaa aattcatatg tttcgaataa aatgaactat
    25921 tatgtttcag cccaagttct tttgcttcca aaaaatcaaa atgataaatc tcatcgattg
    25981 ccggttcatc ttgtgcctgc ttcagcatcg cctcgtgttc tgctttgaag tgattccaaa
    26041 aaaataacac aatttttgca ttggtaaatg ggcgcacgcg tcgagccatc tccatatcaa
    26101 atccataatc taaaaaaacg atcagctgat aatttgccaa ctgttgtcta gctgatttaa
    26161 tgaattccga ctgtagtaaa tcttttccgg accaaacatc taaagagcgg atggaaggca
    26221 aaaaataaag tgatttattt tttgcaacta gcagtacgtc atttttgttc atcttttccg
    26281 cctcactttc tctgtcactt tttcctatga tagcctgttt aaatagtaaa aagccagtaa
    26341 aacgtttcct atatttgtat gaaaatttaa catttgtatg aaaatatgat gaaataaatc
    26401 attcttctat taaaattcgc ctaaaagttt tctgaatagt tgtaattgtc tgaaaatttg
    26461 ttatcattag tcattgttaa atattgctat ttattcttaa tataaatttt gattgtgaat
    26521 ttaaaagaaa gaggtcattt atggaagata aaaaattgaa aaaacaactt agctccagac
    26581 atatcaccat gttagcttta ggtggagcaa tcggtgcagg tctatttaaa ggaagtggcg
    26641 aagcgattgg gatcgccggc ccttctgtat tgattgcttt tttgattggt gggctgattt
    26701 tatatatcgt gatgaaaggt ctgggaaaaa tcgttttaag cggtggcgac acgcatcacg
    26761 gattatctgg tttgatacgc ccttatctag gtgctcattc tgctgatttt actgattggg
    26821 tctactggtc tatgtggatt atcaatatca tcgctgaagc tgttgcagct gcttcctttt
    26881 tgcagttgtg gttcccgcac attccagcct gggtatttgt ttttatgttg gctgttttaa
    26941 ctacgatcat caatctttat tcggtacggt tattcgcaga aacagaatat tggctggctt
    27001 ttgctaaaat cagtgtcatt atcttactga tcatttttgc tacttatctt gtcggtcagc
    27061 aaatgttggg cacaggcgtt ttccctaccc ttcagcaatt gactgaccat ggtgggttta
    27121 ctcctcatgg tatgaaggga atcatcagtt ctttgcttgt agttatctat tcttacggcg
    27181 gttctgaact gattgctatc acggtaagcg aagcagatga tcctaaacgt gcgattccta
    27241 aagcaatcaa aggtgtcatg ggaagaatca tttcctttta catcattcct ttgtttttgc
    27301 ttttgattct ttttccttgg aatactttag caggcacgaa tgtcagtcct tttgtgatgg
    27361 tatttgaaaa aatgaatatc ccatttgcag cggatatcgt caattttgtg attgtccttg
    27421 ctttgttctc atctatcaat tcgggtgtgt atgcatcttc aagaattttg ttcttccgtt
    27481 tgaaggatcg aaaaggttcc tctagaaaac tagctgtttt aaacaagcat caagtaccgc
    27541 aacgtgctgt tttattttgt accagtgttc tttatcttgg tgtagctctt tcttattttg
    27601 tcggtgacaa attatttggc tatctggcag gttccctttc gtatacagta ttattgatct
    27661 ggatcattat cagtgcggca tcctttgtac tggcactaag aaaaggaaca ttatgggata
    27721 aaggaatcag cttttttgca ttagctgtct taggattgat tttccttggt atcctgttca
    27781 cgaactccat tggggtaact gtattgactg gcctgcttta cctgttcatt tatttcagtt
    27841 atcaaaaaaa gaatgatgcg ttcgtattga cgaatgaatg aaatcgatag aaaattttat
    27901 tttatttatg tggaatagat ggagctattg aagaaaggag ttgtgacaaa agtcttgttg
    27961 caactccttt ttccgaataa acagtctcat gacctcttgg taaacggtgt tcaaaaaccc
    28021 tctgtgcaaa ataattgatt gttctccatg ctcatgacat gatagaagaa aggaatgaaa
    28081 aaaaggagtt tgttttaaat gaaaaagtat tggaagtttt tgttgatgat cggtgtttca
    28141 acggtagtta tgtttggtat gatgtacttg aatgtctatg cgctcgatca tatcttcttc
    28201 agtcgtacac gagtattcat ggcgttgatg atgggtgcag tcatggcagt catcatgctg
    28261 ttgttcatgt ggaaaatgta tgaaaacaaa aagataaatg ttatgatctt agccgctagt
    28321 cttcttgttt ttgccggttc cttgtttatg gtacgaagcc aaactactgt caacgacaca
    28381 gcttggatga aggccatgat tcctcatcat tctatcgcta tcctggcaag taaacgagct
    28441 gatttaaaag atcctgaagt aaaaaaatta gcggaagaaa tcattcaggc acaagaagaa
    28501 gagatcgaca aaatgaaaaa aatgatcaaa gaaatggaat gaccattatc cgtccaaata
    28561 aaaaaagagg atgttccaga agttatcagc ttcaagaaat aagaagaagc tacttctgga
    28621 acgccgtgaa taaggggttg tgaaaaagct gccctgcatc aagtaataag aacagccaaa
    28681 caaaaatagc ttctcctatt tttcgtttgg ttaggcttat taccgcagat gcaagctttt
    28741 gaacaccgtt tattaagagg ttgtaaaatc agcgttctga cctgagtatt agagagacaa
    28801 atggaaaaat agttcctcat attttgccat tttttgagct aataccgagg gtcagctgat
    28861 tgaacaccgt ttatcgagag gttgtgaaaa agtcgcttag tttcgcgtat taagaaaaat
    28921 tttgtgaaat ggctttccac atttttgtat aaatttggct taataccgag aaactggctt
    28981 ttgaataccg tttattcgta aaagggattg tgacaaaagt cttgtcacaa tcccttttta
    29041 tgttt
//
LOCUS       DAFBVQ010000029        28683 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.029, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000029 DAFBVQ010000000
VERSION     DAFBVQ010000029.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 28683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 28683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..28683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.029"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(20..1186)
                     /locus_tag="LLC22_001504"
     CDS             complement(20..1186)
                     /locus_tag="LLC22_001504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291475.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5434787.1"
                     /translation="MEGKNKKNRPVSWFWRWFLNNQVVTALLVVLLILLIVFLFTKVS
                     YLFAPIWQFLAIVGLPIILAGILYYLMNPVVDYFEKRKVPRLYSIIGLFVLVVALIAW
                     GSVVIIPKIQEQTVSFISNFPQYVDTIDNKLTEILRDPLFNQFREQLETAGDKFMNSA
                     GDMIQDISKSTVQSLGSFVGAVATILVALLTMPFILFYLLKDGKQLAPYFVKFLPTRM
                     QKPTLNVLSEMNSQVSSYIRGQLTVAFAVAIMFMIGFAVIGLEYAVTLGIIAGFLNLI
                     PYLGSFLAMIPAIFLAIVAGPFMIIKVLIVFAVEQTIEGRLISPLVLGNQLAIHPVTI
                     LLVLLTSGKLFGIIGVILGIPVYAAAKVVITHVFEWYTTISSLYEENPLKKQKE"
     gene            complement(1198..1551)
                     /locus_tag="LLC22_001505"
     CDS             complement(1198..1551)
                     /locus_tag="LLC22_001505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328164.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBK5434788.1"
                     /translation="MIQAKITEIGTEAINKEEPMLILFDKTATAALRKYSVIQEVSKD
                     EPFSLKAGGTIAFDDQVYTIDYVGPMANGNLKTVAHVSLIFDACPEEGQIANGIYLHP
                     HRLPAIGLGSQIFYN"
     gene            1679..2704
                     /locus_tag="LLC22_001506"
     CDS             1679..2704
                     /locus_tag="LLC22_001506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactonase family protein"
                     /protein_id="HBK5434789.1"
                     /translation="MIEKIILGTYTRRESKGIYTIDLDTEKEELANLSLAVEENSPTY
                     VAKSKAGNLYTVTSVDGLGGAGAYDKDFHFLNAVTESGAPLCYVAVDEARQLLYGANY
                     HKGEVNVYHILGDGELKAADSIFHQEATGPHKNQDHAHVHYTDLTPDQRLVVCDLGTD
                     RVYTYDVSENGKLNLVTTFTAEPGTGPRHLVFHPNGQFAYLFGELDSTVRVLSYNKET
                     GAFEELQKISTLPEEFDGENGGAAIRISNDGKFLYASNRGHNSIAVFAVFEDGSHIQN
                     KQIISTEGDFPRDFALDPSNNFVVCANQNTDNLTLYRRHPETGLLELLKKDVYVPECV
                     CVYFDRS"
     gene            2720..2881
                     /locus_tag="LLC22_001507"
     CDS             2720..2881
                     /locus_tag="LLC22_001507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434790.1"
                     /translation="MNQQDVLDRLREELNIPFFDGKIEDKEYSEEEYQKLKADLQNYF
                     EQYVQNVEN"
     gene            complement(3111..3575)
                     /locus_tag="LLC22_001508"
     CDS             complement(3111..3575)
                     /locus_tag="LLC22_001508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434791.1"
                     /translation="MLPNIGYYVQSIDQIVKETEAIGEGMHPKYEVIRNAIDEGKTSE
                     LDKSTLEEIILLFEEGTKKYRAMLMKVSTLRPPAKAMGIHKNFEKAYLSYVAGCEEMI
                     QSIDLESGVDEDLFNTSEAKQDQATDQLTAAIQKMTNLLLKKIKEIFDNNKN"
     gene            complement(3685..5544)
                     /locus_tag="LLC22_001509"
     CDS             complement(3685..5544)
                     /locus_tag="LLC22_001509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBK5434792.1"
                     /translation="MKRYISRLSTKQKKILKGTAAIISIFFLVVFSNLFLQWCQNDLS
                     VDLALKFAFSWHTEKFFLACLVLLIILIFLIALAGSVPLGSLTYVVAIGVLGFANYMK
                     MSYRQEPIYPDDLKMITEIGLLKDMTGTMLFTVILAAAGTVIGLFCWYMFRSLKKGRR
                     FQLIRLTTLLVAIGLLGYISNFNNPDNLLRKAYNKTALWIPYSQKMNYYNTGFIGGFL
                     YNLKVEPMDEPEGYSKEKIKEITEKYQKLADEKNKTVEEESPNIVFVMSESFSDPSRL
                     NGVEVSGEPLADYYEVADQTYSGNMLSQNYGGGTANIEFEALTGFSMALFNAQLTTPY
                     TMLVPKMDQLPSIVSALNAQSYQTTAIHPYNTSMYKREDVYQTLGFDQFISERTMTYT
                     DTIENNPYISDESAYKEVMTLLKEEKTPQFIHLVTMQTHMPYDGKYDNLDYPAKTSDG
                     SGTLDLENYLQDISYSSTALKQFTEELKNLSRRTLVVFWGDHLPGIYSDTIQAKNDKQ
                     TLHETQFLMFDSKGELEKQTTHDAITSPFYFAANLMEQTNQTTNGFYQLLLSLEQELP
                     AFERELYYQNGQWYKEAQFNRSQQEIYDEYQLIQYDIVAGKQYSLADGFFEHE"
     gene            complement(5662..6821)
                     /locus_tag="LLC22_001510"
                     /pseudo
     CDS             complement(5662..6821)
                     /locus_tag="LLC22_001510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332175.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
     gene            complement(7128..8552)
                     /gene="araA"
                     /locus_tag="LLC22_001511"
     CDS             complement(7128..8552)
                     /gene="araA"
                     /locus_tag="LLC22_001511"
                     /EC_number="5.3.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-arabinose isomerase"
                     /protein_id="HBK5434793.1"
                     /translation="MLNIGEKEFWFVVGSQHLYGEEALREVKKHAQEMVDELNENGQL
                     PYPIRLQELAVTADTITKIMKEVNYREEVAGVITWMHTFSPAKMWIRGTKLLQKPLLH
                     LATQYNESIPWKTIDMDFMNLNQSAHGDREYGFINARLNKQNKIVVGYWKRPEIQKEI
                     ADWMDVAVAYNESFGIKVARFGDNMRNVGVTEGDKVEAQIQFGWTVDYFGIGDLVQVI
                     DRVSDEEVDQLFEEYKELYTFDYGDYEEKTWEEHVKVQAQQEIGIRRFLEEGGYNAFT
                     TNFEDLYGMKQLPGLAVQRLMAEGYGFAGEGDWKTAAIDRLLKIMARGKDTGFMEDYT
                     YELASGQEAILESHMMEVDPTLAATKPRIVVSPLSMGDREDPARLVFDGKAGEGVVVS
                     MADFGTHYKLLINEVEAFEPTTEAPNLPVARVLWKTKPNFHEGVHSWIQAGGGHHTVV
                     SLNLTTDQIETWAKLVELETVVIR"
     gene            complement(8568..9266)
                     /locus_tag="LLC22_001512"
     CDS             complement(8568..9266)
                     /locus_tag="LLC22_001512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005873905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBK5434794.1"
                     /translation="MLEQLKEEVYQANLDLPKHGLVKYTWGNVSAFDPETRYFVIKPS
                     GVSYEEMTADDMVVVDLDNHIIEGKLNPSSDTPTHAVLYRSFPQIGGIVHTHSTWATI
                     WAQAGLDVPAMGTTHADTFYGSVPCARFLTQQEIDSGYEYETGKVIIETFKERKIDPL
                     AIPGVLLHGHGPFTWGKDAQSAVMNAVVLDEVCKMNLFTRQLNSFSEELPQRILDKHY
                     LRKHGKNAYYGQNK"
     gene            complement(9223..10884)
                     /locus_tag="LLC22_001513"
     CDS             complement(9223..10884)
                     /locus_tag="LLC22_001513"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FGGY-family carbohydrate kinase"
                     /protein_id="HBK5434795.1"
                     /translation="MKEVNAQSMLDVIDGRTSLGIEFGSTRIKAVLIDSSFTPIAAGS
                     YEWENKLENGIWTYSLEDIWKGLRVSYRKMAAEVFEIYGENLTTIGSIGFSAMMHGYL
                     AFDSKEQLLVPFRTWRNTITEEAERILTEKFQYNIPQRWSIAHLYQSILNKEEHVKEI
                     NFLTTLAGYVHWQLTGEKVLGVGDASGMFPIDPSTKTYHQEMKNIFGQLIEKAHVAID
                     LDHILPKVLVAGEEAGKLSESGAYLIDPTGNLRPGIPVCPPEGDAGTGMVATNSVAKG
                     TGNISAGTSAFAMIVLEKELENVHPEIDMVTTPSGELVGMVHTNNCSSDINAWVSIFE
                     EFTNSLGMEISRDKLFTVLFNKALEGDTDCGGLLSYGYFSGENITGVNEGRPLFVRTP
                     GSRFDLANFMRIHLASAFGAMRIGMDILKSENVQIDRLVGHGGIFKTPEVGQRILASA
                     MEAPVTVMDTAGEGGAWGIALLAAYMMDRHGKSLENFLAEDVFGQDQGITITPSAEEI
                     AGYQIFMRRYREGIDIEKTAIHQLQEKGVIENAGTTERRSIPSKS"
     gene            11102..12502
                     /locus_tag="LLC22_001514"
     CDS             11102..12502
                     /locus_tag="LLC22_001514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar porter family MFS transporter"
                     /protein_id="HBK5434796.1"
                     /translation="MKKEKKVSSSFIYFFGAFGGILFGYDIGVMTGALPFLQHDWGLA
                     GKASLIGWITSSVMLGAILGGSLSGLLSDKLGRRKMILLSALIFMAGSVLSASAPHNG
                     SYFLIAARILLGLAVGAASALVPAYMSEMAPARLRGRLSGINQVMIASGMLLSYVADY
                     LLKGLPETMAWRVMLGLAAVPALILFFGVLALPESPRFLMQSGRLEEAKRVLNYIRTP
                     KEAEQEFEQIQLNVKQEKTTGTSWHTLFLEKYRSLVIAGIGVAVFQQFQGANAIFYYI
                     PLIVEKATGHAASDALMWPIIQGIILVAGSLLFLVIADKFNRRTLLKIGGSVMGLSFI
                     LPAVLGTVLDAHTNSLLILLFLCIYVAFYSCTWAPLTWVIVGEIFPLAVRGRASGLAS
                     SFNWIGSFLVGLLFPVMTASMSQEIVFGIFGIICFLGVLFIQEIVPETRGKSLEEIEQ
                     SASKKTYPKRISIHHS"
     gene            complement(12754..13833)
                     /locus_tag="LLC22_001515"
     CDS             complement(12754..13833)
                     /locus_tag="LLC22_001515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5434797.1"
                     /translation="MAKYQDIAEEIKQKILREEYEVNTTIPSEFKLQEIYDVSRHTIR
                     QAIAVLVNEGYLRKEKGSGTYVDDSYKKEKTPLNRTKTIGVITTYLSDYIFPSIIRGI
                     ENELRESGYSLLLASTNNDHELEKECLKKMIAYGVDGLIVEPTKSNQYNPNLALYVAL
                     REQGIPMVMINAAYEELNASYICLDDVKVGFMAAEYLIKKGHQRLLFITKIDDLQGKY
                     RMKGFISACEQYNVRFLTEDIITFTTETRETIAEKTVQRLKEEQALDGIICYNDQIAS
                     LMLDKLTENGYHIPDDLSIVGTDDSSLSHLGNKKLTTLTHPKEKLGQDAARWIVTTIE
                     KGQAQPNILYEPVLVERETVKENEK"
     gene            complement(13919..14878)
                     /locus_tag="LLC22_001516"
     CDS             complement(13919..14878)
                     /locus_tag="LLC22_001516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738651.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 43 protein"
                     /protein_id="HBK5434798.1"
                     /translation="MMKTLYNNPIVRQRADPWVYKHTDGYYYFTGSVPGYQVIELRRA
                     KSLNELEHAASLIVWQAHEEGPMSELIWAPEVHYINGKWYIYFAASNHKTIRDESHHH
                     RMFVLENQHIDPMNTDWIEKGQIKTKRETFSLDGTTFSSQGKLYYVWAQQDPEITGNS
                     NLYLSEMDNPWTLKGKQILLSIPEYEWEKRGFSVNEGPAVLTRNGKIFITYSGSATDE
                     NYAMGLLWADEHKNLLLKESWHKLSEPVFVSSEKNKQFGPGHNSFTVSEDGCFDILIY
                     HARPEKNQKGDPLDNPNRHANAQCFTWNEQGFPEFGEPVPYAL"
     gene            complement(14890..16401)
                     /locus_tag="LLC22_001517"
     CDS             complement(14890..16401)
                     /locus_tag="LLC22_001517"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338659.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBK5434799.1"
                     /translation="MKVKIREDFTVGEISSRLFGSFVEHMGSVVYTGIYEPGHETADG
                     DGFRQDVLSYVKELELGVIRYPGGNFTSGYDWVDTVGRKEQRPKKIDLAWRGIEPNSF
                     GLHEFFKWISHVQAKPIFTVNLGTKGIDEAKNLVEYCNFPKGTFWSDLRIKNGQKKPF
                     GVKLWCLGNELDGPWQVGAKSAYEYGRLANEASKVMKLVDDSIETILVGSSTPRLPSY
                     PEWDRIALEEAYENVDYLALHNYIDKYDEEDLTKPPKNERDDTATYLAKAYRFDRQIE
                     EIVATCDYVKGYLRSEKTMYLAFDEWNVHAQPEKRHRDFEVGSPIDWCYFTMEDTLLF
                     GSLGLAILRHADRVKISCQSLLVNTIPLILTDAKGQAWRNPTYYVMQHLSKYAKGQVL
                     KQQIICPVYDCEKIKNVPYVDSVIVDNGNQLTIFLINRTNEQQKITIEHDFNLLDQGE
                     HYTLTSSDLLDKNTREEPEKIKPEINYFSIEKHDELNVGIEKYSWNVIRIKKM"
     gene            complement(16423..16986)
                     /locus_tag="LLC22_001518"
     CDS             complement(16423..16986)
                     /locus_tag="LLC22_001518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YesL family protein"
                     /protein_id="HBK5434800.1"
                     /translation="MKIVETKLYGQLIVVSDYILLGILWVIVCLPVITIVPATCAVFY
                     VMAQWKGEGSGNIIYFFFQGIKQHFGKNLFLSLLTIIIYFLVNQLLEEQTIVLSISGY
                     VVLLIYSMFLLSWIYVISENKDITFLQIFEQSAWKVFFDFLRNILCCVLLLGFVLLIF
                     LFPPFIFIFAGGVWKLVSIILTIGNER"
     gene            complement(16992..17855)
                     /locus_tag="LLC22_001519"
     CDS             complement(16992..17855)
                     /locus_tag="LLC22_001519"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5434801.1"
                     /translation="MAPESSITVTVNSRKAVSGKKIIRTISMLVILLVIAFPFLWLII
                     SSFKHEKDIISFPPRIFADSYTLDNYIKVWTTIPLLDYIKNTVIFAGGTVITSVFFDS
                     LAGYAFARMRFKGKSVLFYFVLLTMMIPFQVFMIPLFIEVNLLGMLDTYAGLIIPRMT
                     TAFGIFMMRSFFITLPDSLEEAARIDGLSEFNIFLKIMLPLSKPTLLSLGIFTLMNSW
                     NDLLYPLILTSSSKMRTLPAGLALFTGQNISFYGPVMAGTVISMLPLLVVYIFAQKYF
                     VQGTAMSGMKE"
     gene            complement(17869..18765)
                     /locus_tag="LLC22_001520"
     CDS             complement(17869..18765)
                     /locus_tag="LLC22_001520"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5434802.1"
                     /translation="MNGFTKYWNRPDRAAYLFLTPSFLVLLLFTVIPLLGTFAISFTD
                     LNIFFTSRNFVSFENFTRIFSDERAVNSLIHSLYFTVLETPTQIIVGLLAAVALSKNT
                     RFNRFCRSTFYIPVICSLTSIAIIFSMLLDPNVGAIPYLFSQVGLPIPQFFRDPTLAM
                     PTVAIMTVWKNFGVTMTILLTAIQGISPSLYESAQMDGATNRQQFFNITLPQIVPSLG
                     FCILTNLIGSMQVFDQVYVATAGGPQFKTETAVQYIYSRGFTAPYELGYASALSSVLF
                     IIVATIAISTNVYMSRKEKQMK"
     gene            complement(18940..20229)
                     /locus_tag="LLC22_001521"
     CDS             complement(18940..20229)
                     /locus_tag="LLC22_001521"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5434803.1"
                     /translation="MKEEQKMKGKKWLIGSLLVAATGILGACGGGSSAESDSDKEVTL
                     TFWNGFTASDGEILQEIVNEFNKTNDKNIKIEMDIMTWANLNEKLPTAISSKKAPDFI
                     ALNYPDFAQYVENGAVQPLDDFWEYDGVDKSDFKETAIELGEVEGKQYFVPMQVQGMY
                     MYWNNDLFKQAGLDTEQPPTTWEELTEMAPKLTDSSKNVSGFVFNKDGTAPLYNWMLA
                     NGGKLVNDDYTKSEFASPENLKTLKAIQKMIHVDKTGPESISGAEMDNLMNAGQLAIE
                     INGPWLNNGLKANEIDYNVTTLPQGSDSDKKTAILDGVGYAIPASTDNNKKEAVYEFL
                     KYWNTTEIGKKWSIENGFPAYLDSVAKDEEVKNDPIVSELSKQMDYAEPYLPGFTQIS
                     AINNDIINPLIEKLLAGEDPETLMNDADDAINQLLQK"
     gene            complement(20201..21718)
                     /locus_tag="LLC22_001522"
     CDS             complement(20201..21718)
                     /locus_tag="LLC22_001522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-N-arabinofuranosidase"
                     /protein_id="HBK5434804.1"
                     /translation="MEATMLISSVKRVGKVDPRLYSSFIEHMGRAVYEGIYQPDHPSA
                     NKSGFRQDVIHLVKELNIPMIRYPGGNFVSGFRWEDSIGPIANRPRRLDLAWRTIETN
                     EVGIHEFYNWCQHVGAEINMAVNLGTRGVDAARNLVEYCNFPKGTYWSDLRRSNGQES
                     PFGIKTWCLGNEMDGPWQIGHKTAEEYGRLAEETAKAMKLVDDSIEVVLCGSSNRQMP
                     TFGDWELTVLDQAYDQIDYLSLHQYYGNQKNDLSHYLARSLDMDRFISEVTAMCDTVK
                     AKKHSKKQINLSFDEWNIWYHSAEQDEQAAPWQIAPPLLEDNYNFEDALLLGCLLITL
                     LKHADRVKIACLAQLVNVIAPIRTETNGEAWRQTIYYPFMQAAVYGQGEVLSPQIRSA
                     NYATEDFEEVPYLESIAVINDKELVIFAVNRGEEEMNLTVHLSELSLEGVIDFSEMSG
                     FDTKATNLPKSEQVKPSHSTNVKAEDGKINCLLKPLSWNVVRCRLSDEGGTKNER"
     gene            21916..22806
                     /locus_tag="LLC22_001523"
     CDS             21916..22806
                     /locus_tag="LLC22_001523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArsR family transcriptional regulator"
                     /protein_id="HBK5434805.1"
                     /translation="MQLQINEESLPVYEALASKTRIKIIQLLSKKKMNVKDLAKELGV
                     SSAITTMHVKKLEEANIIKTEKVGQQKISSLRVDKIDISFPEKIFNAFDTKETSIPIG
                     HYTNYAIEPTCGLATIHDFIGKVDEPRYFMDPRRMDARILWFTSGFVEYQAPNFLNTE
                     DTLEMLEVSVEISSEFPFSNDNWPSDITFSLNGVELGTWTSPGDFADIRGKYTPDWYP
                     DNLNQYGLLKTIRITKHLTNMNGEPLSNITINDIPKEQDTWHLRIEVKDDAKHVGGCT
                     LFGKGFGNYDQDIKLKVYYS"
     gene            complement(22879..23703)
                     /gene="nadE"
                     /locus_tag="LLC22_001524"
     CDS             complement(22879..23703)
                     /gene="nadE"
                     /locus_tag="LLC22_001524"
                     /EC_number="6.3.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonia-dependent NAD(+) synthetase"
                     /protein_id="HBK5434806.1"
                     /translation="MSLQTEIINELGVKPTIDPKEEIRKSIDFMKAYLKKYPFLKTFV
                     LGISGGQDSTLAGRLAQLTMEEMREETKDENYQFIAVRLPYGEQADEEDAKAALDFIQ
                     PDVSLRVNIKPAVDAQVQVLSEAGVGISDFNKGNIKARQRMITQYAVAGERAGAVLGT
                     DHAAENITGFFTKFGDGGADILPLFRLDKRQGKQLLQALNAPEKLYTKIPTADLEDGK
                     PMIADEVALGVTYNEIDDYLEGKEVPAQAQEKIEAWWNKTQHKRHLPISVLDDFWK"
     gene            complement(23715..25187)
                     /locus_tag="LLC22_001525"
     CDS             complement(23715..25187)
                     /locus_tag="LLC22_001525"
                     /EC_number="6.3.4.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287304.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate phosphoribosyltransferase"
                     /protein_id="HBK5434807.1"
                     /translation="MNNTYPDDSLTLHTDLYQINMMQTYWELGRADLHAVFECYFREM
                     PFNHGYAVFAGLERLVNYLENLTFNDSDIAYLRGLEVYPEGFLEYLQNFEFKATVRSA
                     REGELVFANEPLIQVEGPLAHCQLVETALLNMVNFQTLIATKAARIKSVIGEDPLLEF
                     GTRRAQELDAAVWGTRAAYIGGADATSNVRAGKIFGIPASGTHAHSLVQSYGNDYEAF
                     MAYAKTHKDCVFLVDTYDTLKSGVPSAIRVAKELGDKINFQGVRIDSGDMAYISKRVR
                     EQLDAAGFTEAKIYASNDLDEATILNLKMQKAKIDVWGVGTKLITAYDQPALGAVFKL
                     VSIEDDEGKMMDTIKLSSNAEKVTTPGKKQVWRITRNFDGKSEGDYVTLWDEDPREEE
                     AIFMFHPVHTFINKTVRDFTARPVLQDIFIEGKRVYELPALNEIKEYTKENLDSLWEE
                     YKRDLNPQKYPVDLSTECWNHKMAIMERMKKSVAELHTEA"
     gene            complement(25824..26186)
                     /locus_tag="LLC22_001526"
     CDS             complement(25824..26186)
                     /locus_tag="LLC22_001526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBK5434808.1"
                     /translation="MKLIETPVNSNLNIKTFYPKVVEFFFGNTAINYYKLFSLDRTQL
                     LLVDTYDKKQVVMINTKKKITRQEIDYAIHHVLKMTREDVKVHVGVKQELERAGIQFK
                     RPNKDIVVIEQKNTKDSI"
     gene            26409..27161
                     /locus_tag="LLC22_001527"
     CDS             26409..27161
                     /locus_tag="LLC22_001527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5434809.1"
                     /translation="MEYTIKKMSEISGVSPRTLRFYDEIGLLKPARINSSGYRIYGKK
                     EVDRLQHILFYRTMAFKLDDIQEVLDNPSFDHQKALIKHQQMLLEKRAQIDTLLTTVQ
                     QTLDMYEGGRKMSDKEKFEGFKQQKLKENEESYGQEIRQKYGKKKVTASNEKWMNMDK
                     ETYEEMQTVEKQMLFDLTLYLKEPEDESLADRIFQAHKKWFSYSWPEYQPKAHKGLGM
                     MYEADERFTAYYDERSGHGAAKALNEIIQKKA"
     gene            complement(27301..28224)
                     /locus_tag="LLC22_001528"
     CDS             complement(27301..28224)
                     /locus_tag="LLC22_001528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434810.1"
                     /translation="MANIRDIAKLTGYSVSTISRVINGHPYVDEEKRKEILAVMKEVD
                     YIPNANARQLSYGKTKSIGVILPYTNHPYFDQLISGIIEAAFDYDYKVTLLPTGYHKE
                     KERRYLEEFAAKAFDGLIITSRANTLDDLLAYQKYGPLVFCEEIKGKQASCVFIDREQ
                     SITEGLTYLKQQGIKQLGITLGRSGRLSYNSKITLQLCHQLFPSFDESLVFWDCIDAE
                     KGKQAGFFFKELGVDGVFTNSDMVAAGILQSYLQDKTPVVIGRDNLLISELLGFPTID
                     HHLEACGEMAFQLFLTEKKDKVKIPYTFIQR"
     gene            complement(28239..28511)
                     /locus_tag="LLC22_001529"
     CDS             complement(28239..28511)
                     /locus_tag="LLC22_001529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434811.1"
                     /translation="MNTYVEITDGTTNNYFYAFVEFKGSVLTLYSFQGLNRNIVKEIP
                     MNEIENLTKDIYWGGQRISFSHEGKMYQFFECGPAVVDYLQENLFV"
BASE COUNT         8477 a         5988 c         4884 g         9334 t
ORIGIN      
        1 tcccatctgt ctctttttgt tattctttct gctttttcaa cggattttct tcataaagag
       61 aagagattgt tgtgtaccat tcaaaaacat gagtaatcac tactttagct gctgcataaa
      121 caggaatccc caagatcaca ccgatgattc cgaacaattt cccagaagtc agcagaacta
      181 ataaaatcgt tactggatgg attgctaact gattccctag tactaatgga gagatcaagc
      241 gtccttctat tgtctgctct actgcaaaaa cgatcagtac tttgatgatc atgaatggac
      301 ctgctacaat ggctaaaaag atagccggaa tcatcgctaa aaatgatcct aagtaaggga
      361 tcaggtttaa aaaacccgca ataatcccca acgtgacagc atactctaaa ccaatgaccg
      421 caaaaccaat cataaacatg attgccacag caaaagccac agttagttgt cctcttatat
      481 aagaagaaac ttgactattc atttcactca gcacattcaa cgtcggtttt tgcatgcgtg
      541 tcggtaaaaa tttgacaaaa taaggtgcta attgtttacc gtctttcaat agataaaata
      601 agataaacgg catcgtcagc agagccacta aaatagtcgc taccgcgccg acaaaacttc
      661 caagactctg aactgtactc ttagatatat cttggatcat atcgcctgcc gaattcatga
      721 acttatcacc tgctgtttcc aactgttcgc gaaattggtt gaacagcggg tcccgcaaaa
      781 tctcggttaa tttattatca atcgtatcta catattgagg gaagttactg atgaagctca
      841 ctgtttgttc ctgaatctta gggatgatca ctacgctccc ccatgcgatt agtgcaacaa
      901 ccaaaacaaa cagcccaatg atactgtaaa gccttggtac ttttcgcttt tcaaagtaat
      961 caactaccgg attcatcaag taatacaaga ttcctgctaa aatgataggc agacctacga
     1021 ttgctaaaaa ttgccagatt ggtgcaaaca aatatgaaac ttttgtaaat aaaaagacga
     1081 tcagcaatat taacaataca acaagtaagg ctgtgactac ttgattattt aaaaaccagc
     1141 gccaaaacca cgataccggt ctgttcttct tattttttcc ttccataatt cctcctgtta
     1201 gttataaaaa atttggcttc ccaaaccaat agcaggcagt ctatgcggat gaagatagat
     1261 tccatttgca atttgtcctt cttctggaca agcatcaaaa atcaatgata cgtgagctac
     1321 tgtctttaaa ttcccattgg ccatcggacc gacataatcg atcgtatata cctgatcatc
     1381 aaaagcaatt gttccgcctg ctttcaaaga aaaaggttcg tcttttgata cttcttgaat
     1441 caccgaatat tttcgtaagg cagctgttgc tgttttatcg aacaaaatca gcatgggttc
     1501 ttccttgttt attgcttctg tcccaatttc tgtaatcttt gcctgaatca ttgcactctc
     1561 tcctttaatt gctttcaaaa acagtataac acattctcat tctttagccg tgtggaataa
     1621 ttatgtgata gaataaaaac gaaaactatt tcattacaat taggaggaat cagctcatat
     1681 gatcgaaaag ataattttag gaacctatac gcgtcgcgaa agtaaaggaa tctatacgat
     1741 cgaccttgat acagaaaaag aagaattagc caacctttca ttagctgttg aagaaaatag
     1801 ccctacctat gtagcaaaaa gtaaagctgg caatctttac acagttacta gtgtggatgg
     1861 attaggtggt gccggtgcgt acgataagga ttttcatttt ttgaatgcgg taacagagtc
     1921 tggcgctcct ttgtgttatg tagcggttga tgaagcacgt caattactat acggggcgaa
     1981 ctatcataaa ggtgaagtaa atgtctacca tatattagga gatggcgaac tgaaagcagc
     2041 agattcaata ttccatcaag aagcgacagg tcctcataaa aaccaagatc atgcgcatgt
     2101 ccactatacg gatctgactc ctgaccaacg attagtcgta tgtgatcttg gtacagatcg
     2161 tgtgtatact tatgatgtgt ccgaaaacgg caaattgaat cttgtaacta ccttcactgc
     2221 agagccagga acaggccctc gccatcttgt ctttcatcca aatggacaat tcgcttattt
     2281 atttggtgaa ttagacagca cagtccgcgt gctttcttat aataaagaaa caggtgcttt
     2341 tgaagaatta cagaaaatat cgaccttgcc agaagaattc gacggtgaaa atggaggggc
     2401 agctatccgc atttcaaatg atggcaagtt cctttatgct tctaaccgag gacataactc
     2461 gattgctgta ttcgcagttt ttgaagatgg ttcccacatt caaaacaagc aaatcatctc
     2521 aacagaaggg gattttcccc gcgatttcgc actagatcca agcaataatt ttgtcgtgtg
     2581 tgccaatcag aacaccgata atctgacatt atatcgccgt catcctgaaa caggattact
     2641 ggaattactg aaaaaagatg tctatgtacc agaatgtgtc tgtgtttatt ttgatcgttc
     2701 gtaagaaaag gagaatgaaa tgaatcagca agacgtatta gacagactac gggaagaact
     2761 aaatattcct ttctttgatg ggaaaatcga agataaagag tatagcgaag aggaatatca
     2821 gaaactcaaa gccgatttac agaactactt tgaacaatat gtacagaatg tagaaaacta
     2881 atcagctttc catactatct gaaaagaaca tcaggacaag acttttccgt ctatcctgat
     2941 gttcttttct acaaataaaa aaccgccgag atggttagac tcgacggaaa aggagtattt
     3001 actcgatttt gagtaagtac aaggttgttg ttggttatag gtatgtcatt atcataaagg
     3061 attttgatca ctctatcata aaggtaatat tacatttata ttagataact ctagttttta
     3121 ttgttatcaa agatttcttt tatttttttc aacaacaaat tagtcatttt ttggatggca
     3181 gctgtcaatt ggtctgtcgc ttggtcttgt tttgcttcag atgtattgaa tagatcttca
     3241 tctacccctg attcaagatc gatactttgg atcatttctt cacagcctgc tacatatgaa
     3301 agataagctt tttcaaaatt tttatgaatg cccattgctt ttgctggtgg acgcaaagta
     3361 ctgactttca taagcattgc ccgatatttt tttgttcctt cttcaaataa caggatgatc
     3421 tcttcaagag tcgatttgtc cagttcactt gtttttcctt catcaattgc gtttctgatc
     3481 acttcatatt tcggatgcat tccttctccg attgcttctg tttccttgac gatttgatcg
     3541 atggactgca cataatagcc aatattcggt aacatgttcg ttttcctact ttctccattg
     3601 ttgttattat ttattctact tgtttttatc ctcaaatgac aagtacttga aaaaatttaa
     3661 tggtttctat acagctcgcc attcttattc gtgctcaaag aaaccatctg ctaaactata
     3721 ttgtttccct gcgacaatgt catattggat caattgatat tcgtcgtaaa tctcttgttg
     3781 cgagcgattg aattgcgctt ctttatacca ctgtccgttt tgatagtaca gttctcgttc
     3841 aaacgccgga agttcctgtt ctaatgataa aagcagctga taaaagccat ttgttgtctg
     3901 attcgtctgt tccattagat tcgctgcaaa ataaaacgga ctggtgattg catcgtgagt
     3961 cgtttgcttt tctaattctc ctttactgtc gaacataaga aattgtgttt catgcaatgt
     4021 ttgtttgtca ttttttgctt ggatcgtatc tgaatagatc cctggaagat gatcccccca
     4081 aaaaacaact aaagtccttc tagaaagatt cttcaattct tccgtgaact gcttcagtgc
     4141 cgtgctgcta taggaaatat cttgcagata attctctaag tcaagtgtcc cacttccatc
     4201 tgaagttttt gcaggatagt ctagattatc atactttcca tcgtagggca tatgtgtctg
     4261 catcgtgact aaatgaatga actgaggtgt tttttcttcc ttgagaagtg tcattacttc
     4321 tttgtaagct gactcatcag aaatatatgg attattctct atcgtatccg tataggtcat
     4381 cgtacgctcg ctgatgaact ggtcaaatcc taatgtctga taaacatcct ctcttttata
     4441 catcgaagta ttgtatggat ggatcgctgt cgtctggtat gattgtgcgt ttaacgctga
     4501 aacgatagaa ggaagctgat ccatttttgg tacaagcatc gtgtaagggg tggtgagttg
     4561 cgcattaaat aacgccatag aaaaaccagt caatgcttca aattcgatat ttgctgttcc
     4621 accgccatag ttttgagaaa gcatattgcc actatatgtt tgatcagcta cttcataata
     4681 atctgccaat ggctcaccag atacttctac gccgtttaat cgactaggat ctgagaaact
     4741 ttcactcatc acgaacacga tgttcggcga ctcttcctct acagttttat ttttttcatc
     4801 ggctagcttc tggtattttt cagtgatttc tttgatcttt tctttcgaat atccttcagg
     4861 ttcatccatt ggttctacct tcagattgta caaaaaccca ccgataaaac cagtgttata
     4921 gtagttcatt ttctggctgt aaggtatcca tagtgccgtt ttattatatg cttttcgcaa
     4981 caaattatcg ggattgttga aattactgat ataccctagc agtccaattg ccacaagcag
     5041 tgtcgttaat cggatcaatt ggaatcgcct tccttttttc aggcttcgaa acatgtacca
     5101 gcaaaacaat cctatcacgg ttcctgcggc agctaagatc actgtaaaca gcatagtgcc
     5161 ggtcatatct ttcagcaatc cgatttcagt gatcatcttc aaatcgtctg gataaatcgg
     5221 ttcttgccga taactcattt tcatataatt tgcaaaacct aatacaccga tggctacgac
     5281 atacgtaagg gaacctaaag ggacagatcc tgctagtgca atcagaaaaa taagaataat
     5341 cagcaagacg agacaggcta agaagaattt ttccgtatgc caagaaaaag caaatttcaa
     5401 cgcaaggtct acggatagat cattttgaca ccactgcaaa aataaattac taaaaacaac
     5461 aagaaaaaag atactgatga ttgctgctgt tccttttaaa atctttttct gtttggtcga
     5521 aagtctgctt atatatcttt tcaaatgctt gctccttcat ttctatcaat aaaagaatgt
     5581 tgcttctctt attttagttg tacgaaattc gaaagtaaag aacggaaaga agaattaatg
     5641 aaatccaaat attctctttc tttatggcct ttctggtttc tttaataagc ggacctttcg
     5701 tactccagaa attttttcta gctgttgttt cacttgattg agctgttcaa aatcagtact
     5761 gtctatgtca atcaatatgt agacatgctc attcttatgg ttacgcgata tatctgcgat
     5821 cgctagctcg ttctcattca gcagagaaaa tatctctgct aatatattgg ttttcttttg
     5881 ataaaatata gtgaatcgaa acggcgcttg gaaaaacatt cgtgcggatg gataattgac
     5941 cgcttctcta accgtaccga acaaaagata atcttttaag gcttcaactg ccaaacgtcc
     6001 gctgtctgcc aaagcttcct gagtcgatcc cctagatgag gcaacataag tatacggtca
     6061 ttttctaaga actcttcttc tggaaaatca gtcaagtatt tagccagatg ttgtttttcc
     6121 aatgcttgca taacagcata tttatcaaca atttcacttc ttcctacatt gataagtaca
     6181 gcatcttttt tcattttttc tatattcgcc tgatcgatca atccttttgt atcttctgtc
     6241 aacggcagca tgactacgat gtaatccgag gtagaaagaa ctgtttctaa atctgcttgc
     6301 cgaacataat ccaactgggc atcgcggata gaataaccca agacatccat ccctaagcta
     6361 tagcaactta gcgctacttt tgtgcctatc gctccaagac caagaagacc gatggttttg
     6421 ccttgcaatt ctcgtcccac ataagcactt cttttgtttt ctgcctgttc taaaatatta
     6481 ggacctgtta gtgtttgtac catacgactt gcttcgatta tcggacggga agataagagc
     6541 aaacagcaca aaacaagctc ttttactgca ttagcattta cacctggtgt attcatgacg
     6601 atcgtcccgt tttcagaagc tttttcaacg ttgatcgtgt tcaccccaac accagctctt
     6661 gaaattgcta gcaaatctgg tgtaagccat tcatctttca ctttcgtact acgaataact
     6721 attccttcgg ctggcaaatc atctattatt ttgaaatatt ccccttgtaa cttttctatc
     6781 tcttgttctg gaatagcatc aatcaaatga acgtgataca taaaaccccc tccttactaa
     6841 caagtatctc gaaatttctg caattagaca actgtttacc atttgacttc ctagaagcaa
     6901 aaagagcagt tagagcagag taggctgagt gataaaaata aggctatgac aagttactgc
     6961 cataagcctt attttcgaga gcaaaatatt gagggtgaga tatcttgata aatggtgttc
     7021 cgttagctga cattgataat aagactaaat ttcaaaaaag ttgaaaagca aatttcgtca
     7081 atctcttctt atttcttaaa actaagtggc tttttcacaa cctcttttta tctaataacc
     7141 actgtttcca actcaactaa ttttgcccac gtttcaattt gatctgttgt tagatttagc
     7201 gagacaacgg tatgatgacc gccacctgcc tgaatccatg aatggacacc ttcatggaaa
     7261 ttcggtttag ttttccataa cacacgtgca acaggtaaat taggtgcttc agtcgttggt
     7321 tcaaaggctt ctacttcatt gatcagcagt ttataatgcg taccgaaatc tgccatcgat
     7381 acgactaccc cttctcctgc tttcccatca aatacaagac gcgccggatc ttctctatct
     7441 cccattgata aaggagaaac aacgattctt ggtttcgtcg cagcaagcgt cggatctact
     7501 tccatcatat gggattccaa gattgcttct tggccactag ctagctcgta agtataatct
     7561 tccatgaatc ctgtatcttt ccctcgagcc atgattttca gcaaccgatc aatcgctgca
     7621 gttttccagt cgccttcccc agcaaaaccg tatccttctg ccatcaaacg ttgtacagct
     7681 agtccaggta gttgtttcat tccatacagg tcttcaaaat tagtcgtaaa agcgttatag
     7741 cctccttctt ctaagaaacg gcgaataccg atttcctgct gagcttgtac ttttacatgt
     7801 tcctcccatg tcttttcttc ataatcacca tagtcgaagg tatacaattc cttgtactct
     7861 tcaaataatt gatcgacttc ttcgtctgat acgcgatcga ttacttgtac aagatctccg
     7921 ataccaaaat aatcaacagt ccaaccaaat tgaatctgtg cttccacttt gtctccttct
     7981 gtgacaccca cgtttctcat gttgtcacca aaacgagcca cttttattcc aaaactttca
     8041 ttataggcta ctgcaacatc catccaatca gcaatctctt tttggatctc aggtcgtttc
     8101 cagtagccaa cgacgatttt attttgttta tttaatcgag cattgatgaa cccatattcg
     8161 cggtcaccat gagcggattg atttaaattc atgaaatcca tatcgatcgt tttccaagga
     8221 atgctttcgt tatattgcgt agctaaatga agcaatggtt tttgtagaag ctttgtcccg
     8281 cggatccaca tttttgctgg tgagaaagta tgcatccaag tgatcacacc tgctacttct
     8341 tctcgataat tgacctcttt catgattttt gtgatcgtat cagcagtaac tgctaattct
     8401 tgaaggcgga ttggataagg caattggcca ttttcattca gttcatcgac catttcttgt
     8461 gcatgtttct ttacttctcg cagtgcttct tccccatata aatgctgtga tcctacaaca
     8521 aaccaaaatt ctttttctcc aatattcaac ataattagcc actcctttta tttgttttgt
     8581 ccgtaatacg cattttttcc gtgttttcgt aaataatgtt tatctaaaat ccgttgaggc
     8641 agctcttctg aaaatgaatt gagctgtctg gtaaataaat tcatcttgca tacttcatct
     8701 agtacgactg cgttcattac cgcactttgc gcatctttcc cccaagtaaa tggaccgtgt
     8761 ccgtgtaaaa gtacccctgg aattgctaag ggatcaattt tgcgttcttt gaatgtttct
     8821 atgataactt ttcctgtttc atattcgtac ccgctgtcga tttcctgttg tgtcaaaaat
     8881 cgagcacaag gtaccgatcc ataaaaagta tctgcatgcg tcgtccccat cgcaggaaca
     8941 tccaatcctg cttgtgccca gatcgtcgcc catgtcgagt gagtatggac gattcctccg
     9001 atttgaggaa atgaacgata taaaacagca tgagtaggcg tatccgaaga gggattgagt
     9061 ttaccttcaa tgatatgatt gtccaagtcc acaacgacca tgtcgtctgc tgtcatctct
     9121 tcataactga ctccgctagg tttgataacg aaatatcgtg tttcaggatc aaaagcgctc
     9181 acatttcccc atgtatattt gacgagtccg tgtttaggca agtcaagatt tgcttggtat
     9241 acttcttctt tcagttgttc cagcattttc tatcactcct ttttcttgca attgatgaat
     9301 cgctgttttt tcaatgtcga tcccctcacg gtaacgtctc ataaatatct gatagcctgc
     9361 tatttcttct gctgaaggtg tgatggtgat tccttggtct tgtccaaaca cgtcttctgc
     9421 caagaagttt tctaaagact tcccatgtcg atccatcata taggctgcta ataacgcgat
     9481 tccccacgct ccaccttctc cggctgtgtc catcactgta actggtgcct ccatagcaga
     9541 tgctagaatc cgctgtccaa cttctggtgt tttaaaaatc cccccatgcc ccactaaacg
     9601 atcaatttgg acattctcag atttcaatat atccattccg attctcattg caccaaaagc
     9661 actggctaaa tggatccgca tgaaattcgc taaatcaaaa cggctacctg gtgtacgtac
     9721 aaataatggc cttccttcat ttactcctgt aatgttttca ccggaaaaat aaccataaga
     9781 aagtaatccc ccgcaatccg tatcgccttc tagcgctttg ttgaataata ccgtgaataa
     9841 tttatctctg cttatctcca tacccaaaga attggtaaat tcttcaaaaa tactgaccca
     9901 agcattgata tccgaagagc agttattcgt atgaaccatg cctactagtt ctcctgaagg
     9961 tgtagtgacc atgtcgattt ccggatggac attttctagt tctttttcta atacgatcat
    10021 agcgaaggcg gaagtaccag ccgaaatgtt ccctgtccct ttggctacac tgttcgtagc
    10081 gaccataccg gttcctgcat ccccttctgg cggacaaacc gggattcctg gtctcaaatt
    10141 tcccgtaggg tcgatcagat aagcccctga ttcgcttaac ttgccagctt cttctcctgc
    10201 tactagaact ttaggcaaaa tgtgatccaa gtcaatcgct acgtgcgctt tttcgattaa
    10261 ctgaccaaaa atatttttca tttcttgatg gtaggttttc gttgaaggat cgataggaaa
    10321 catgcctgat gcatctccta cgcctagtac tttctcacca gtaagctgcc aatggacata
    10381 acctgcaagc gttgtcaaaa aattaatttc tttcacatgt tcttctttat tcaaaataga
    10441 ttgatacaaa tgagcgatac tccatctctg cggaatattg tattgaaatt tttccgttaa
    10501 tattcgttct gcttcttcag tgattgtatt tcgccaagta cgaaatggta ctagtaactg
    10561 ttccttgcta tcaaatgcta gataaccgtg catcattgca ctgaacccaa tcgacccgat
    10621 tgtcgtaaga ttctcgccat agatttcgaa tacttctgct gccatttttc ggtaactgac
    10681 gcgcagtcct ttccaaatat cttctaatga ataggtccag ataccatttt ctagtttgtt
    10741 ttcccactca taactaccag cggcaatagg agtaaaagat gaatcaatca atacagcttt
    10801 gatcctagtt gatccaaact caatccctaa agatgtacga ccatctatga catctaacat
    10861 actttgcgca tttacttcct tcataatgat ttaactccct ccttctcgtc aaacctgatc
    10921 aaaccgtctt tttagtagcg cttacaatga ttattgtata cttttgtacg tacatgtcaa
    10981 gcagttattt acaagaatac aataaaaaac acttgttttg tacgtacata agttataaaa
    11041 tgaaattgct tacaaaatct gatcaaccgc cttctcgaaa ttctagaagg agagaatact
    11101 tatgaaaaaa gaaaaaaaag tttcctcatc gtttatttat ttttttggcg catttggcgg
    11161 cattctattt ggatatgata ttggtgttat gaccggcgcc ttaccttttt tacagcatga
    11221 ttggggtttg gcaggtaaag cttctttgat aggatggatc acgtcttcgg tcatgttagg
    11281 tgcgatcctt ggcggctctt tatctggtct tctttctgat aagcttggac gacgaaaaat
    11341 gattcttctt tctgcactta tttttatggc tggttctgtc ctttctgcat ctgcccctca
    11401 caatggttct tattttctga ttgcagcaag gattcttcta ggtttagctg ttggcgctgc
    11461 atctgcccta gttcctgctt atatgtctga aatggctcct gctagactaa ggggaagatt
    11521 gtcagggatc aatcaagtga tgattgcttc tggcatgctc ctttcctatg ttgcagatta
    11581 tttgctaaaa gggttgcctg aaacgatggc ttggcgcgtg atgttagggc tcgctgctgt
    11641 ccccgcgctg attttatttt tcggtgtttt agctctacca gagtcaccgc gttttcttat
    11701 gcaatctggc cgcttggaag aggcaaaaag agtattgaac tatattcgga caccaaaaga
    11761 agctgaacag gaattcgaac aaatccagct gaatgtcaaa caagaaaaga caaccggaac
    11821 ttcttggcat actttgtttt tagaaaaata tcgttcctta gtcattgccg gtattggtgt
    11881 agcagtattc cagcaatttc aaggagctaa tgctattttt tactatattc cgctgatcgt
    11941 agaaaaagcg actgggcatg cagcgagcga tgcattgatg tggccgatca tccaaggaat
    12001 cattttagtt gctggttctt tgctcttttt ggttattgca gacaagttca atcggcgaac
    12061 tttattgaaa ataggcggta gcgtgatggg actttctttc atcctaccag ctgttttagg
    12121 aactgtactg gatgctcata caaattcgtt gttgattctc ttgtttttat gtatttatgt
    12181 cgcattttat tcttgcacat gggctccact gacatgggta atcgtaggcg aaatattccc
    12241 actagctgtc cgcgggcgag catctggcct agcctcttct tttaattgga ttggttcttt
    12301 cctagttggc ttgctttttc ctgtgatgac tgcttctatg tctcaagaaa tcgttttcgg
    12361 catttttggg atcatctgct ttttaggggt tttatttatt caagagatcg taccagaaac
    12421 tcgtgggaaa tctttagagg aaatcgaaca aagtgcatct aaaaaaactt atcctaaacg
    12481 tatttctatc catcattctt aaagaggttg tgacagaagt ggtcagcttc aagaaataag
    12541 aaggaaccgc ttagtttcca gtcacaagga acaatttcaa aaaacagctt ctcatgtttg
    12601 atgaatattg tgacttgtga ccagttggta ggagaacacc gtttagtgga gaggtggtga
    12661 aagaaacgtt cagccttgag cgatgacaaa agctctcaca aacattgcga cgagtaaccg
    12721 taggagcaat aagaggcggt aaaaacccgt ctcttatttt tcgttttctt tcactgtttc
    12781 ccgttcaact agtacaggtt catagagaat atttggctgt gcctgtcctt tttcaatcgt
    12841 tgtgacgatc caccgtgcgg catcttgtcc caacttttct tttggatgcg tcaatgttgt
    12901 caatttttta ttccctaaat ggcttaaaga agaatcgtct gttcctacga tcgataggtc
    12961 atctggaata tgatagccat tttctgtcaa cttatctagc attaaactag ctatttgatc
    13021 gttatagcaa atgatgccat ctaaagcttg ttcttctttc aaccgttgta ctgttttttc
    13081 agcgattgtt tctcgtgttt ccgtggtgaa agtaatgata tcttccgtca aaaaacgcac
    13141 attatactgt tcacacgcgc tgataaaacc tttcatcctg tattttcctt gaagatcgtc
    13201 gatttttgtg atgaacaaca gacgctgatg tccttttttt atcaaatatt ctgctgccat
    13261 aaaaccgact ttcacatcat ctaaacaaat ataagaggca tttaactctt cataagcagc
    13321 attgatcatc accatcggaa tgccttgttc tctcaaagca acataaagtg ctaagtttgg
    13381 gttatactga ttacttttcg taggctcaac gatcaaacca tctaccccat aagcaatcat
    13441 tttcttcaaa cactctttct ccaattcgtg atcgttattc gtactggcta aaagcaatga
    13501 atacccagat tctcgtaatt cattttcgat tcctcggata atcgacggaa aaatataatc
    13561 agagagatat gtggtgatga caccgatcgt ttttgttctg ttcaatggtg ttttttcttt
    13621 cttatagctg tcatctacat atgtgcccga ccctttttct ttacgcagat agccctcatt
    13681 taccaacaca gcgattgctt gccgaatcgt atgtctgctg acgtcatata tttcttgcag
    13741 cttgaattct gagggaatgg ttgtatttac ttcgtattcc tcacgaagga tcttttgttt
    13801 tatctcttct gcaatatctt gatattttgc catttgcctt gccccttttt atttgtacgt
    13861 acatatatca taacgagtct gcaaggttta ttcaagcaaa aatcaaggtt tcttgtgctc
    13921 ataaggcata cggaacaggt tcaccaaatt ctggaaatcc ttgctcattc cacgtaaagc
    13981 attgcgcgtt cgcgtgccga ttaggattgt ctaacggatc ccctttttgg ttcttctctg
    14041 gtcgagcatg atagatcaaa atatcaaagc acccgtcttc tgaaaccgta aacgagttgt
    14101 gaccaggacc aaattgctta tttttttcag aagaaacgaa tactggctcc gataatttat
    14161 gccatgattc ttttaataaa agattcttgt gctcatcagc ccacagcagg cccatggcat
    14221 agttttcatc tgttgcacta ccagaatacg taatgaatat tttcccattg cgagtaagga
    14281 ctgctggacc ttcatttact gaaaaacccc gtttttccca ttcatactca ggtatagaaa
    14341 ggaggatctg cttccccttt aacgtccaag gattatccat ttcggataga taaagattag
    14401 aattcccagt aatttcagga tcttgttggg cccacacata atatagcttt ccttgagaag
    14461 agaaagttgt tccgtctaaa ctgaaagttt cccttttcgt ttttatttgt cccttttcta
    14521 tccaatctgt attcattgga tctatatgct gattttcaag tacgaacatg cggtgatgat
    14581 gagattcatc acgtatagtt ttatgattgc ttgcagcaaa gtaaatatac cattttccat
    14641 tgatataatg gacttcaggt gcccagatca attcactcat cggtccttct tcatgagcct
    14701 gccatacaat caggcttgca gcatgttcta attcattcag tgactttgcc cttcttaatt
    14761 caatcacttg gtagcctgga accgatcctg taaaataata ataaccatct gtatgtttat
    14821 atacccaagg atctgcccgt tgccgaacga taggattatt ataaagtgtc ttcatcataa
    14881 caaatttcct cacattttct ttattctaat tacattccaa gagtattttt ctatccctac
    14941 atttaattcg tcatgttttt ctattgaaaa atagtttatt tcaggtttta ttttttctgg
    15001 ttcttcacgt gtatttttgt ccaacagatc gctactggtt aatgtgtagt gctctccttg
    15061 atctagcaaa ttgaaatcat gttcaatcgt tatcttttgt tgttcatttg tgcgattgat
    15121 caagaaaata gtcagctgat tgccgttatc tacgatcaca ctgtccacat aaggaacatt
    15181 ttttatcttt tcacaatcat aaacagggca aatgatttgt tgtttcaata cttgaccttt
    15241 agcatatttc gataagtgtt gcatcacata ataagttgga ttcctccatg cttgtccttt
    15301 agcatctgtc agtattaaag gtattgtgtt tactaacaat gattgacaac taatctttac
    15361 gcgatctgcg tgtcgtaaaa tagccagccc taatgaacca aataataatg tatcttccat
    15421 agtaaagtaa caccaatcga tgggactacc gacttcaaaa tccctatgtc ttttttccgg
    15481 ttgggcatgt acattccatt catcaaacgc tagatacatt gttttctcac ttctcaaata
    15541 tccttttaca taatcacaag tagcaacgat ttcttcaatt tgacgatcga atcgataagc
    15601 ttttgcaagg tatgtcgctg tatcatcacg ctcattttta ggaggtttag tcaagtcttc
    15661 ttcatcatac ttatcaatat agttatgcaa agctaaataa tctacattct cataagcttc
    15721 ttctaatgcg atacgatccc attcagggta cgatggtaaa cgtggcgtag agcttccaac
    15781 taagattgtt tcaattgaat catccactaa cttcatgact tttgaggctt catttgctaa
    15841 cctaccatat tcataagcac tcttagcccc cacttgccat ggaccgtcta gctcattccc
    15901 taaacaccat aatttaacgc caaaaggctt tttttgccca ttttttattc ttaaatcact
    15961 ccagaaggtt ccttttggaa aattacaata ttctactaaa ttttttgctt catcaattcc
    16021 ttttgttcct aaattcaccg tgaatatcgg tttcgcttgt acatgactga tccatttaaa
    16081 aaattcgtgg agtccaaaag aatttggttc tatacctcgc catgctaaat caattttttt
    16141 tggtcgttgt tctttcctac ctacagtatc cacccaatca taaccagatg taaagtttcc
    16201 tccaggatag cgaatgacac ctaattctaa ttcctttaca taagagagga catcttgtct
    16261 aaacccgtca ccatcagctg tttcatggcc cggttcataa atccctgtat agacgacact
    16321 tcccatatgc tcaacaaatg agccaaacag ccgagaactg atctctccta ccgtaaaatc
    16381 ctctctgatt tttactttca cttcttcgtc caacagcttt ccctaccttt catttcctat
    16441 agtcaagata atagatacaa gtttccatac gccaccagca aagataaaaa taaaaggagg
    16501 gaaaagaaat atgagcagta caaatcctaa taacaatacg caacaaagaa tatttctcaa
    16561 aaaatcaaaa aatactttcc atgcactttg ttcaaaaatt tgtaaaaatg tgatatcttt
    16621 gttttcagaa atcacatata tccaggataa aagaaacatg gaataaataa gtaaaactac
    16681 atatccacta attgaaagta cgattgtctg ttcttctaat aattgattaa caagaaaata
    16741 aataatgatc gttaacagac taaggaacaa gttcttacca aaatgttgct ttattccttg
    16801 aaagaaaaaa taaatgatat ttcctgatcc ctcacctttc cattgcgcca ttacataaaa
    16861 aacagcacat gtagcaggca cgatagtaat aacaggcaaa cacacgatta cccagagaat
    16921 acctaataag atgtaatcag aaaccacaat caactgtcca taaagtttag tctcaactat
    16981 tttcatcttc ctcactcttt cattccagac atagctgttc cttgaacaaa atatttctgt
    17041 gcaaaaatat aaaccactag taatggcagc attgaaataa ccgttccagc cattacaggt
    17101 ccataaaaag aaatgttctg ccctgtaaat aaagctaacc ctgctggtaa agttctcatt
    17161 tttgaactac ttgtcaatat caatggataa agcaagtcat tccaactatt catcagcgtg
    17221 aaaatcccta atgataaaag agtaggtttg ctcaatggca acatgatttt caaaaaaata
    17281 ttaaactcac ttaatccatc aatgcgtgct gcctcttcca aagaatctgg taaagtaata
    17341 aaaaaggaac gcatcatgaa gataccaaat gcagttgtca tacgaggaat gatcaaacct
    17401 gcataagtat caagcatgcc aagcaaattg acttcaataa atagaggaat catgaagact
    17461 tggaatggga tcatcattgt cagcaaaacg aaatagaaca aaactgattt tcctttgaaa
    17521 cgcatacgag caaatgcata ccccgcaaga gaatcaaaga atacagaagt gatcactgtc
    17581 cctccagcaa aaatcactgt atttttgatg taatctaata aagggatcgt tgtccaaacc
    17641 ttaatatagt tatctagggt atagctatct gcaaatattc taggcggaaa tgagataatg
    17701 tctttttcgt gtttaaaaga agaaataatc agccacaaaa aaggaaacgc aataaccaac
    17761 aatataacta gcatactaat cgttcgaatg atttttttac cactaactgc ttttcgacta
    17821 ttcacagtaa ctgtaatcga gctttctggt gccatacagg tttccctcct atttcatttg
    17881 tttttctttc cgtgacatgt acacattagt ggagatagct atagttgcaa caatgataaa
    17941 caaaaccgaa gacagtgctg atgcatagcc caattcataa ggtgctgtaa atcctcgact
    18001 gtaaatatat tgaacagctg tttctgtctt aaattgtggg ccaccagcgg ttgcaacata
    18061 tacttggtca aacacttgca tcgaaccaat cagattcgtt aaaatacaaa aacctaagga
    18121 gggaacgatc tgaggtagcg taatgttaaa aaactgctgt cgatttgttg caccatccat
    18181 ttgagcagat tcatacaaag agggagagat tccctgaata gcagtcaaga gaatcgtcat
    18241 agtaacacca aaattcttcc aaacagtcat gatggctacc gtcggcatag caagggttgg
    18301 atcgcgaaaa aattgaggga tcggcaagcc gacttgtgaa aacaagtaag gaatcgcccc
    18361 tacattcgga tcaagcaaca tagaaaaaat aatcgcaatt gacgtcaatg aacaaataac
    18421 tggaatgtaa aatgtcgaac gacaaaaacg attgaatctg gtatttttag ataatgctac
    18481 tgctgctaat aaaccaacga taatttgtgt tggcgtttcg agtacggtga aatataaaga
    18541 atgaatcaac gaattaactg ctcgttcatc actaaatata cgtgtgaaat tttcaaaact
    18601 tacaaaattt cttgatgtaa agaaaatatt caaatctgta aaactaatag caaatgttcc
    18661 taaaagcggt atgacagtaa ataataataa aactaaaaaa gatggagtta aaaacaaata
    18721 cgcagcacga tcaggacgat tccaatattt ggtgaatccg ttcatatagt ccacctcatc
    18781 tttcattttg ataaaatata caatcttggt ttaaacgaat ctgaataaga tatccgaaca
    18841 atcgctgtga tttttgcaat aacacctatc tgcaaatact aggtcgatca ttcagatatc
    18901 tgtatcttgc caacagtcta tcctgtataa agttctgtac tatttttgca gtaattgatt
    18961 gatggcatca tctgcatcgt tcatgagtgt ctcaggatct tctcctgcta ataatttttc
    19021 aatcagtgga ttgatgatat cgttattgat cgcagagatt tgggtaaaac ctggtaaata
    19081 tggctctgca tagtccattt gtttcgataa ttcagataca ataggatcat tttttacttc
    19141 ttcatctttt gctactgaat ccaagtaggc aggaaaacca ttttcgatac tccatttttt
    19201 accaatttca gttgtattcc aatatttcaa aaactcatag acagcttctt ttttattatt
    19261 atctgtactt gccggaatgg catatcctac gccatctaaa atagctgttt ttttgtctga
    19321 atcactccct tgtggtaagg tagtcacatt ataatcaatc tcgtttgctt tcaatccgtt
    19381 atttaaccat ggcccattga tttcaatggc tagttgacca gcattcatta aattgtccat
    19441 ttcggcgcca gaaatcgatt ctggaccagt cttgtctaca tggatcattt tttggatcgc
    19501 ttttaacgtt ttaaggttct caggagacgc aaattcagac ttagtataat catcgttcac
    19561 taatttaccg ccatttgcta acatccagtt atataacggt gcagttccat ccttattgaa
    19621 gacaaaacct gatacatttt tactactatc agttaatttt ggtgccattt ctgtcaattc
    19681 ttcccaagta gtaggtggtt gttcagtatc taatccagct tgtttaaaca aatcattatt
    19741 ccaatacata tacatgcctt gtacctgcat ggggacaaaa tactgtttac cttctacttc
    19801 acctaattca atagccgttt ctttaaaatc agatttatct actccatcat attcccagaa
    19861 atcgtctaat ggttgtaccg ctccgttttc tacatactgt gcaaaatctg gataatttaa
    19921 tgcaataaag tcaggtgctt ttttagaaga aatcgctgta ggaagttttt cattcaaatt
    19981 ggcccaagtc atgatatcca tttcaatttt gatgttttta tcatttgttt tattaaattc
    20041 attaacgatt tcttgcaata tttcaccatc agatgcagta aacccattcc aaaaagtcaa
    20101 agtcacttct ttatcagaat cagattctgc tgaacttccg ccaccgcaag ctcctaaaat
    20161 acctgttgca gctaccaaca aagagccaat taaccatttt ttacctttca ttttttgttc
    20221 ctccttcatc tgataaacga catctgacca cattccaaga tagcggtttc aataaacaat
    20281 tgattttccc atcttcagct tttacatttg ttgaatgact tggttttact tgttcacttt
    20341 taggaagatt agttgctttt gtatcaaatc cactcatttc agaaaaatca atcactccct
    20401 ctaatgataa ttcagacaag tgaacagtta gattcatttc ttcttctcca cggttaactg
    20461 caaatatgac aagttctttg tcatttatta cggctatact ttctaaatac ggcacttctt
    20521 caaaatcttc cgtcgcatag tttgctgaac gaatttgtgg gcttaacacc tctccttgtc
    20581 catacacagc agcttgcata aatggataat agatcgtctg tctccaagct tctccgtttg
    20641 tttctgtcct gattggtgca ataacattta ccaattgagc aagacaagca atctttactc
    20701 tatctgcatg tttcaataaa gtgattaata gacagcctaa tagtaatgca tcttcaaaat
    20761 tatagttatc ttctagtaaa ggaggagcaa tctgccaagg cgctgcttgc tcatcttgtt
    20821 ccgctgaatg ataccaaata ttccattcat caaaggacag gttgatctgc ttcttactat
    20881 gtttcttcgc cttgactgta tcgcacatcg ctgtcacttc agaaatgaac cgatccatgt
    20941 ctaaggaacg tgcaagataa tgagaaagat catttttttg gttgccataa tattgatgca
    21001 gagacaaata atctatttga tcgtacgctt gatcaagaac tgttaactcc caatcaccaa
    21061 atgtaggcat ttgccgattc gaacttccgc ataaaaccac ctcaattgaa tcatctacga
    21121 gtttcatcgc cttagccgtt tcctctgcta accgtccata ttcttccgct gttttatgtc
    21181 caatctgcca aggaccgtcc atttcattcc ctaaacacca tgtcttaatt ccaaaagggc
    21241 tctcttgacc attcgaacgc cttaaatcac tccaataagt tcctttagga aaattacaat
    21301 attcgactaa attacgagct gcatctactc cacgagtacc cagattgaca gccatattga
    21361 tttcggcccc cacatgctga caccagttat aaaattcatg aatcccaact tcattcgttt
    21421 caattgtccg ccaagctaaa tccaaccttc taggtctatt tgctatgggc ccaatactgt
    21481 cttcccaacg aaatcctgac acaaaatttc caccaggata tctaatcatg ggaatgttca
    21541 attcttttac caagtgaatg acgtcttggc gaaatccact tttattagct gatggatgat
    21601 ctggctgata aatcccttca tatactgctc gtcccatatg ttcaataaat gaactgtaca
    21661 accgcggatc aactttgcct acacgcttga cactactaat caacattgtg gcttccataa
    21721 ctgacctcct ttaatttata catgaataat acacctcgtt gaaagcgttg tcaataatat
    21781 aaatgttaaa cttacttatt ttttatcgat tttaattaac caaaatatta ataatgatta
    21841 aaacaaataa tttaatataa cttttattaa caaatatgtt aatatataag aaaaaccttt
    21901 taagaggtga tatatatgca actacaaata aacgaagaat ccttaccggt atatgaagca
    21961 ttagctagta aaacaaggat caagatcatc cagctacttt ccaaaaaaaa gatgaatgtc
    22021 aaagatttgg caaaagaact tggagtgagc agtgctatca cgacgatgca cgtgaaaaag
    22081 ctagaggaag caaacatcat caaaacagaa aaagtaggac aacaaaaaat ttcgagcctt
    22141 cgtgtcgata aaatcgatat cagttttcca gaaaaaatat tcaatgcttt tgatacgaaa
    22201 gaaacatcga tacctattgg tcactataca aattatgcaa ttgaaccaac atgcggttta
    22261 gctacgatcc atgattttat cgggaaagtg gatgaaccac gctattttat ggatcctcga
    22321 aggatggatg cccgcattct ctggtttacc agcggatttg tcgagtatca ggcacctaat
    22381 tttttaaata cagaggatac attggagatg ttggaagttt ctgtggaaat ttcttctgaa
    22441 tttccttttt caaatgacaa ttggccttca gatatcactt tcagcctaaa tggtgtggag
    22501 ctaggaacat ggacgagccc tggagatttt gctgatatcc gcggtaaata tacgcctgat
    22561 tggtatccag ataatcttaa tcaatacggc ttgctgaaga cgatccgaat taccaaacac
    22621 ttgacgaata tgaatggaga acccttgtca aacatcacga tcaacgacat ccctaaagag
    22681 caagacactt ggcatttgcg aatcgaagtg aaagacgatg ccaaacatgt ggggggctgt
    22741 actttatttg gtaaaggatt cggtaattac gatcaggata tcaaattaaa agtttactac
    22801 agctgatatt tttcttttct attttataaa acaaaaacag ccaatcccta tgaagggacg
    22861 gctgtttttg ctttattgtt atttccagaa atcatccaaa acggaaattg gcaaatgtcg
    22921 tttatgttgt gtcttgttcc accatgcttc gattttttct tgtgcttgag cgggaacttc
    22981 ttttccttct agataatcat caatttcatt atatgtgaca cctagtgcga cttcatctgc
    23041 aatcattggt ttcccatctt caagatctgc agtcggaatt tttgtgtata atttttccgg
    23101 tgcattcaat gcttgaagca attgtttccc ttgtcgtttg tccaaacgga ataatggcaa
    23161 aatgtcggct ccaccatcac caaatttcgt gaagaatcca gtaatgtttt ctgcagcatg
    23221 atctgtccct aatacggctc ctgctctttc tccagctacg gcatattgcg taatcatacg
    23281 ttgacgtgct ttgatatttc ctttgttaaa atcgctgatt cccacacctg cttcgcttaa
    23341 tacttgtact tgtgcatcaa cagctggttt gatatttact cgcagactaa catcgggctg
    23401 gataaagtca agagcagctt ttgcatcttc ttcatctgct tgttcaccat aaggaagacg
    23461 aacagcgata aattgatagt tttcatcttt tgtttcttca cgcatttctt ccatcgttag
    23521 ttgcgccaaa cggcctgcta aagtagaatc ttggccgccg ctgataccta gtacaaaagt
    23581 tttaagaaac ggatattttt tcaaatatgc tttcataaag tcaatacttt tacgtatttc
    23641 ttcttttgga tcaattgttg gtttgacacc taattcattg ataatttctg tctgcaggct
    23701 catttattct cctcctatgc ttctgtatga agttctgcta cgcttttttt cattcgttcc
    23761 atgatagcca ttttatggtt ccagcattca gtagacagat cgactgggta tttttgcgga
    23821 ttcaagtctc gtttatactc ttcccatagt gaatctagat tttcttttgt atattctttg
    23881 atttcgttta gtgcaggtaa ttcgtaaact ctttttcctt cgataaagat atcttgtaaa
    23941 actgggcgag ctgtaaagtc tcgaacagtt ttattgataa acgtatgcac tggatggaac
    24001 atgaagatag cttcttcttc tcgagggtct tcatcccata atgtcacgta gtctccttca
    24061 gatttcccat caaaatttcg agtgatgcgc cacacttgtt ttttccctgg agtagttact
    24121 ttttctgcat tgcttgataa cttgatcgta tccatcattt ttccttcatc atcttcgatc
    24181 gatactagct tgaatactgc accaagggct ggctgatcat aggctgtgat caattttgtc
    24241 ccaacacccc atacatcaat tttagctttt tgcatcttta aattcaaaat cgttgcttca
    24301 tccaagtcat tcgaagcata gatttttgct tccgtaaatc cggctgcatc taattgttcc
    24361 cgaacacgct tagatatata ggccatatct ccactgtcga tgcgtacgcc ttggaagttg
    24421 attttgtcac ctaattcttt cgccacgcga atcgcacttg gcacacctga tttcaacgta
    24481 tcataagtgt cgactaagaa cacgcagtct ttatgggttt tagcgtaggc cataaatgct
    24541 tcataatcat ttccataaga ttggactaac gaatgagcat gggtcccgct agctggtatc
    24601 ccaaatatct tcccagcacg tacattgctt gttgcatctg ctccgccgat atatgccgct
    24661 ctagttcccc agactgctgc atccagttct tgtgcccgtc tagttccaaa ttccaatagt
    24721 ggatcttctc cgatgacaga tttgatacga gctgcttttg tcgcgatcaa cgtttggaaa
    24781 ttgaccatat tcaacagtgc tgtttctact aattggcagt gcgctaaagg cccttccact
    24841 tggattaatg gttcatttgc aaaaactagt tctccttcac gagcagaacg aactgttgct
    24901 ttaaattcaa aattttgtaa atactccaaa aaaccttcag gatagacttc taatccacgc
    24961 aagtaagcaa tatcggaatc attgaacgtc agattctcta aataattgac taaccgttcc
    25021 aatcctgcaa aaaccgcgta tccgtggtta aaaggcattt ctcgaaagta acattcaaaa
    25081 acagcatgta aatcagctcg acctaattcc cagtatgtct gcatcatatt gatttgatat
    25141 agatccgtat gcagcgtcaa actgtcgtct gggtaagtat tattcatctt gtattactcc
    25201 tcttggcaag ttttcatttc ctacccatta taacaaaaaa aattaatagg aaaagaaatc
    25261 ttccattttt tctgaaaaag cacatgtttt acggatattt cttgctaaaa atgaactcca
    25321 tctgctaaaa ctatcctttc ttattggtat ttaacctaaa cgagaaagaa tacttatttt
    25381 attcaatgta tccgagacac gaagaaatta gcgttttcta tttttcttac ttgataaaat
    25441 aagtagattt tcctactaca atcgtagccg ttaagatacc gatgattgaa caaatataac
    25501 caaatgtctc tacaacataa tcaatggcaa aagtttttga agcaataata cgtctttcct
    25561 tttttgcttc ttatccccaa agaaacggat ataacttatt atgtattgaa tttttttgga
    25621 aaggcgaatt atgacaagat ataccttgcg ttgaaaaaac tcgcggaaaa aatatcacac
    25681 gtttttaaaa agatacaaag taagaaagca gctgtcaata gaatggaaac aaaaatggcg
    25741 agacatcaat cagtctcgcc ttgtttttta ttgtatacat tagatatgga gcaggttacc
    25801 ataaagatga ttattagtcg ttattaaata gaatccttcg tatttttttg ttctatcact
    25861 acaatatctt tatttggacg tttgaattgt attccggcac gttctagctc ctgtttcact
    25921 cctacatgga ctttgacatc ttctcgtgtc atttttaaaa cgtgatgaat cgcatagtcg
    25981 atttcttgcc ttgtgatttt tttcttcgta ttgatcatca cgacttgctt tttatcatat
    26041 gtgtctacca atagcagttg tgttcgatct aacgaaaata atttgtaata attaatagcc
    26101 gtattcccaa aaaagaattc cactacttta ggataaaatg tcttaatatt taaattacta
    26161 ttcacaggtg tttcgattag cttcatctca ttcctctttt ctatatagtc gatttagatc
    26221 caatcttaag ttatgttacc atctttccta gcattaagga atcggttaca attgaacctt
    26281 taaagacaaa aggatttacc ttttatcact taatagtata acataatttc gtgagaaaaa
    26341 aatacaattt tttcttgacc atctcgttac gtaaaggatt atgcttacat ttgtcaggag
    26401 gaaaaataat ggagtacaca ataaagaaaa tgtcagagat atcaggagtc agtccgagaa
    26461 ccttgcgctt ttatgatgag attggactgc taaaaccagc taggatcaat tcttcaggtt
    26521 atcggattta tggcaaaaaa gaagtcgatc gtctgcaaca catcttattt tatcgaacaa
    26581 tggcattcaa gttggatgat atccaagagg tcttagacaa tccatctttt gaccaccaga
    26641 aagctttaat caagcatcag caaatgttgc tggaaaaacg ggcacaaatc gataccctct
    26701 tgacaactgt ccaacagaca cttgatatgt acgaaggagg aagaaaaatg agtgacaaag
    26761 aaaaatttga agggtttaaa caacaaaagt tgaaagaaaa tgaagaatcc tatggacaag
    26821 agattcgaca aaaatacgga aaaaaaaagg ttacagcatc caatgaaaaa tggatgaata
    26881 tggataaaga aacgtatgaa gaaatgcaaa ctgttgaaaa gcagatgtta tttgatctca
    26941 ctctttactt aaaagaacca gaagatgaaa gcttagcaga ccgtatcttc caagctcata
    27001 agaagtggtt ctcttacagc tggcctgaat atcagccaaa agcgcataaa ggactaggaa
    27061 tgatgtacga agccgatgaa cggttcactg catattatga cgagcgaagt ggtcatggtg
    27121 cagcaaaagc tttaaatgaa attatccaaa aaaaggcgta atcttttaca tgatccaaca
    27181 aaaaagtaca cgtaaaatga cctaataaca aaacagcaga cacccaagtt agatttttat
    27241 gctaactttt ggtgtctgct ccattctttc acaagttttt tcatcctact ttaaatatat
    27301 tcatcgttga ataaacgtat aaggtatttt cactttatcc tttttttctg taagaaacaa
    27361 ttgaaatgcc atttctccgc aagcttccag atggtggtcg atggttggga aaccaagaag
    27421 ctcgctgatc agcaaattat cgcgtccaat caccactggt gtcttatctt gcagatagct
    27481 ttgcaagatg cctgctgcaa ccatatccga atttgtaaag acaccatcaa ctccaagctc
    27541 tttaaaaaag aagcctgctt gttttccttt ctctgcatct atacaatccc aaaaaacaag
    27601 tgattcatca aaagatggaa aaagttgatg acatagctgc aaagtgattt ttgagttata
    27661 acttagcctg ccacttcgcc ccaacgtgat gcccaattgc tttatacctt gctgcttcaa
    27721 ataagtaaga ccttctgtaa ttgattgttc tcgatcaata aagacacagc ttgcctgttt
    27781 tcccttgatt tcttcacaaa aaactagagg tccatatttt tgatatgcca ataaatcatc
    27841 tagtgtattg gcacgagacg taatgatcaa tccatcgaaa gctttagctg caaattcttc
    27901 aagatacctt cgctcttttt ctttatgata gcccgtcggt aaaagtgtca ctttgtaatc
    27961 ataatcaaac gctgcttcaa tgatcccact gatcaactga tcaaaatacg gatgattggt
    28021 ataaggcaga atcactccaa tgcttttcgt ttttccataa cttaactgtc tggcatttgc
    28081 attagggata taatcgactt ctttcatgac cgcaagtatt tctttccttt tttcctcatc
    28141 tacatatgga tgtccattga ttacacgtga aatagtagaa actgaataac ctgtgagctt
    28201 tgcgatatct cgaatgtttg ccactgctgc ttcgccacct atacaaaaag attttcttgt
    28261 aaatagtcta ccacagctgg accgcattca aaaaactgat acatttttcc ttcatgcgaa
    28321 aaactgatcc gctgcccgcc ccaatatata tcttttgtca aattttcgat ttcattcatt
    28381 ggtatttctt ttactatatt cctattcaac ccttgaaaac tgtacaacgt taatacggat
    28441 cccttgaact cgacaaacgc ataaaaataa ttgttcgttg tgccatctgt tatctctaca
    28501 taagtattca ttgcaagccc tccttttgat actttgagta tagtgtatga aacgcgtctc
    28561 atagcaagga gtttgttttg ccaaagaaaa gttttattcc tctttcatta ttaccaaagt
    28621 ctcttatttt aaattgaata cattataatg atactgtaaa tatatcttta ttattagtga
    28681 atg
//
LOCUS       DAFBVQ010000030        27633 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.030, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000030 DAFBVQ010000000
VERSION     DAFBVQ010000030.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27633)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27633)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27633
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.030"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            119..766
                     /locus_tag="LLC22_001530"
     CDS             119..766
                     /locus_tag="LLC22_001530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBK5434812.1"
                     /translation="MKKTVIYTSLFAALFLAACQSNTNQGTSGNTSSSSEQRSSQVSD
                     SSTKASTSSSSQTKSSSEASTQSDIKVSAARAIELFQDKYPDTAITSLELDSDWGSYF
                     YKIEGVDDQKEYEARIDAQNEKMETENPETLDRDEQNGQKKKEDGLDVDKLITIEEAA
                     KIAVDKVGSGTATDWDLDKDLGTTYWEVKVKDGNQSTSVKINSQTGEVLSTEQDD"
     gene            850..1794
                     /locus_tag="LLC22_001531"
     CDS             850..1794
                     /locus_tag="LLC22_001531"
                     /EC_number="1.3.98.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290739.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydroorotate oxidase"
                     /protein_id="HBK5434813.1"
                     /translation="MSLETTFANHIFANPLMNASGVHCMTTQELDELAHSEAGAFITK
                     SCTINERKGNPEPRYFDVPLGSINSMGLPNLGFSYYLEYALAYEKVQENQNQPLFFSI
                     AGMSVQENLEMLEKIEKSGFNGITELNLSCPNVPGKPQLAYDFEATYETLKEVFSIFS
                     KPLGIKLPPYFDFAHFDQMADILNQFPLTYVNAINSVGNGLYIDTEQEAVVIKPKEGF
                     GGIGGEYIKPTALANVRAFYTRLKPEIQIIGTGGIRTGQDAFEHLLCGASMLQIGTEL
                     HKEGPEIFSRIIKELTQIMSEKGYTSIDEFKGKLRTIS"
     gene            1929..3380
                     /locus_tag="LLC22_001532"
     CDS             1929..3380
                     /locus_tag="LLC22_001532"
                     /EC_number="3.5.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332411.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidase"
                     /protein_id="HBK5434814.1"
                     /translation="MNDATELAKELKEKEFSFQELVTDIQKKIKKQNHELNAFVALEP
                     FESNSHELLIPQSEKGPLAGIPFPLKMLGQEKKGWLATSGSRLFETHRASHTSNYVRQ
                     AEAIGLVPFGQTNAPEFGFKNITDPVIYGPARNPWNLECTPGGSSGGAAAAVSSGIVP
                     LAGASDGGGSIRIPASFCGLIGLKPSRGTMPVGPYAWRGWQGAAIDFGLTVSMRDTEA
                     LFYGMRSIHSGAPYQVSPVEWQTHPRKKRLKIAFCVDSPIHSQISEEAVLAVKKAVDF
                     LGKEGHDLTEIPYPLDGRKLITSYYQMNGAETAAMIRSIETGIQRAVRKEELEPISWT
                     LFQYGQKLSAATYIDSLHVWDEAAIVMENLHQEYDLFLSPTTAFTAPKISEDLQSDAI
                     RAQMEHISDCSEVEGLDVVSSMFEESLKITPYTQLANLTGQPAISLPTHLTKENMPLG
                     IQFMAARGREDLLFQIGYLFEANHQFHLPNPWK"
     gene            3401..4237
                     /locus_tag="LLC22_001533"
     CDS             3401..4237
                     /locus_tag="LLC22_001533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transporter substrate-binding domain-containing
                     protein"
                     /protein_id="HBK5434815.1"
                     /translation="MKKKRLFALITSAFFILSACGTAAANQEDNSWSNVEKKKELVVA
                     TSGTLFPASYYNDQNELVGYDVDLAKEVAKRLNVKISFKEYNVDGQITSVSKRESDFA
                     ANDFGITKEREKKFSLSETFKYSFDSMIVRKKDDSGIHSLEDLKGKKAAGEPNTSYMR
                     LAEKHGAKLVTYDNATNDQYLSDVANGRTDVILNDYYLQKMAVSALPDIPVKILENVY
                     FNENESGFLLKEGNDALKKKIDGVLKEMKEDGTTKKISEKYFQTDVSVKPKETMAESV
                     SE"
     gene            4237..4896
                     /locus_tag="LLC22_001534"
     CDS             4237..4896
                     /locus_tag="LLC22_001534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265363.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter permease"
                     /protein_id="HBK5434816.1"
                     /translation="MYFPLIDFSLMWTSLPFVLQGLVYTLGIGFVSFLLGNLVGLLLT
                     VLGLLDWLPLNVFIRFYLSFFRGIPALVLLFLLYFGLPYQLSALTASVICFTITSSAF
                     IGEIYRGSLAGVSSGQWDAGLASGFSFFGVLKYIVLPQAFRISVPALSNVAMDLVKGT
                     SLAATITVPEIFQKAKIIGGRTFDYFSLYILVALIYWVICIGIEKVQQYLEKRSMHQS
                     I"
     gene            5022..5711
                     /locus_tag="LLC22_001535"
     CDS             5022..5711
                     /locus_tag="LLC22_001535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853260.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434817.1"
                     /translation="MKTPLTIEIESSLYQYCIEQGGLVVEEVTMPDDQGIVDTLSCLT
                     KFDGSREWRCYELKVTKADFRSTAKLSFVGHYNYFVLPSKLYEEVKTEIPTGIGVLVY
                     RPYTVEEEMPASGTFLIAKKAAKKELAVPEEALTNRFMASLFREVRKAKQMERGVKYF
                     PTDQLYKELKRRSENQDPFSNERYYERFLEEIASQAINELQEEVIALQHDYEYLRQQQ
                     QIRRLPTEPLE"
     gene            5717..6673
                     /locus_tag="LLC22_001536"
     CDS             5717..6673
                     /locus_tag="LLC22_001536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302005.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sce7725 family protein"
                     /protein_id="HBK5434818.1"
                     /translation="MYYPYLRGKQFDLLALKEALSRGLLSNKIQPVIEPVRDSATLKN
                     VIELFQKKHHRIAVIQNPQVGQFKLFDQHVHSWTVKENSSVVPAQILTPENLSEVLDS
                     PPAFLVFDGQHYPKDTEVWKQLAGVDSKFLIPDTSRFRIWLPENKIVIRDSFQTRKHV
                     ESYADKTDDFFSDDYLFFHADGYIGFSDFTIEGSRYFDKGFPSRALAIHLTYIDAYGN
                     IRVKHFVSDSNDSAKDQALKFLEAGDKMKKWIMRHHHQLLITSGMIELLALYQQQKFP
                     GLGVLKKWSLMHHLELISHLLDHPKDWLKYYSKVQELYEVIQ"
     gene            6717..7229
                     /locus_tag="LLC22_001537"
     CDS             6717..7229
                     /locus_tag="LLC22_001537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302625.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434819.1"
                     /translation="MYIRQTRKEEVEEVVEIINAAADFIASQGSPQWQNGQKPTKETI
                     LNDIERKESYVLIVEDQIAGTAALVSSVDPVYTKIDGSWKESTGPYLSIHRVALAEST
                     RGKKLAKPFLEHLLTIAASKNIQDIRIDTYPANEPMEKTIYSAGFTYQGMIEFPFEHG
                     ERKAYQIIIN"
     gene            complement(7485..8033)
                     /locus_tag="LLC22_001538"
     CDS             complement(7485..8033)
                     /locus_tag="LLC22_001538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5434820.1"
                     /translation="MNYCYVFIGPSGSGKTSLAEAIFQPEQKIITYTNRSPRPGEKDQ
                     EDYYFVSDNTFNQMIKGNEFAEWDQYAQHKYGSSKAEIKKKLTVGNCYAVLTANGFWH
                     LYEYFGTVVRPIFITISKETLQSRLKKRGDSSEQISARLAVYVEDLAQLKRLKAIPSL
                     LVVSNDGAFQEAADKIKKGLLI"
     gene            complement(8122..9303)
                     /locus_tag="LLC22_001539"
     CDS             complement(8122..9303)
                     /locus_tag="LLC22_001539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NupC/NupG family nucleoside CNT transporter"
                     /protein_id="HBK5434821.1"
                     /translation="MSYLLGIIGLFVTLGLAFLISSNKKAIKLKPLIVMFVLQLVLGF
                     VLLRTTFGTAVVSVLAKMFDHLLAFAGQGVDFVFAGVANKGSAPFFLSVLMPIVFISA
                     IIGILRYIKILPLFMKAVGLGLSKINGMGKLESYNGVASAILGQSEVFISIKKELPFL
                     SEKRLFTMSVSAMSTVSMSIVGSYMALIDSKYVITALVLNLFGGYILASIVNPYVLEE
                     KEDELIIEENKEQTFFQMLGEYILDGFHVAITVAAMLIGFVALIAMINAIFHGIFGIT
                     FQEILGYIFAPLAFISGIPWKEAVDAGSIMATKLVTNEFVAMTELANGNFHFTERTTA
                     IISVFLVSFANFSSIGIISGAMKGLNEEKGNLVAKHGLKILLTATLVSFLSAIVTGLL
                     V"
     gene            complement(9539..11047)
                     /locus_tag="LLC22_001540"
     CDS             complement(9539..11047)
                     /locus_tag="LLC22_001540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1846 domain-containing protein"
                     /protein_id="HBK5434822.1"
                     /translation="MKKIGFDSEKYIEEQSAYILERVNHYDKLYLEFGGKLVDDKHAK
                     RVLPGFEEDAKIKLLQKLKDQAEILICVYAGDIERNKIRGDYGITYDMDILRLIDELR
                     GYGLLINSVVITRYSGQPATKVFINKLERRNIKVYKHSEIEDYPVNVEKIVSEDGFGK
                     NEYIETTKPIVVVTAPGPGSGKLATSLNQLYHESQKGHAAGYSKFETFPVWNVPLKHP
                     LNIAYEAATVDLKDVNMIDSFHFDAYNKVAVNYNRDVETFPVIKRIIEKITGKESVYQ
                     SPTDMGVNRVGFGIVDDTVVQEASKQEIIRRYFQTECDFKKGLIDEEAVNRIKLIMEE
                     VGLRPEDRNVVVPAHDYADKIQAQSPTKDPSAVIAIELPDEVIITGRTSSLMDASAAV
                     ILNAVKHLAHIADDIPLLSPLVLETIQGLKSKTLHSSLDALSINEVLIALSISAVTNP
                     IAQVAYDKLAELEGAQAHSTVMVNKNDEQTLKKLGIDITCAPVYPSENLYYQ"
     gene            11206..11397
                     /locus_tag="LLC22_001541"
     CDS             11206..11397
                     /locus_tag="LLC22_001541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434823.1"
                     /translation="MKKRQKKKNAYKHYIRSIFTGYERMLEDPELEQLTFTYLNEETQ
                     LTRDEHQRIHFTTRDLPSK"
     gene            11600..12517
                     /locus_tag="LLC22_001542"
     CDS             11600..12517
                     /locus_tag="LLC22_001542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="viral A-type inclusion protein"
                     /protein_id="HBK5434824.1"
                     /translation="MKEPDTNANYEPDELEETNADQDTGQESSSFYDIKEKASMNLSQ
                     LLEDLQAFEKAVREEDIPEIYRLYNGRLNEELKRSSNENHEIDQLLMRKIHDRFLQEF
                     PFMEQVENISPTMSYYKIGTYYHDRPTVGIDASLPEIFVLPKIDEEWEKYSQPESTDY
                     DKKINELDAKVITAQTEIERLDEQIKEINRQMTDLNDNKGFLNRKKIEEEIQELEKKK
                     QVLSNEKLGWLPYIETPETIQQQKEALKQEARADQLRAAIVEKEQRQIRRYFGSKEGF
                     GQAIHEFLMNYLGNENPNNQSNEGGSEYE"
     gene            12510..13583
                     /locus_tag="LLC22_001543"
     CDS             12510..13583
                     /locus_tag="LLC22_001543"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344237.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434825.1"
                     /translation="MNEHDEAEWTKNEEQTEDHEETNTSLEEQTSNPLDDTEEIPMLE
                     ETKIHEKEKVTPTNTNTAENTHAYEITENPGYLEGKEQDHQDIVSLIETAEAELADLR
                     MRKDLIESDFPQLLESYDRFILNEEPISTIGKTSLIEYFTYELLKPLNDIGLERSNSA
                     YDTWKTRHFSINYTLNGQNELVFSFVLPTIDQRYQVESMSLLNVSPETMEINVQDDRV
                     LSLIRHWSVDRVFSAGQITIFNHKLNQLLAHARTLGFTVNQTLLDNTKPLRLNLQSEF
                     ELTNEVLDDIFIVAMKNPSYDMEKINETTYQVRLDKGQSLTITTNEKDQTVLSISSGD
                     YPRSVIDFFINYEFLVPLMVRKS"
     gene            13731..14249
                     /locus_tag="LLC22_001544"
     CDS             13731..14249
                     /locus_tag="LLC22_001544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434826.1"
                     /translation="MSTNKIAQLSLLSAACVAGRIAFQFIPNFQPMTAIFLFIVLYLS
                     LKDALIVMSLSIAISSFYFGVGPWVIGQWISYTVVLSLFSIVCLRKTVQRNLWLKGVC
                     FFLAGMVYGIGMTVFDTLLYRLPQPWIYYLQGVSFDLMHSIGNVVFFLVFLPVVKRFY
                     NHSGGKNEKNNL"
     gene            14230..14622
                     /locus_tag="LLC22_001545"
     CDS             14230..14622
                     /locus_tag="LLC22_001545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4430 domain-containing protein"
                     /protein_id="HBK5434827.1"
                     /translation="MKKIIYSLLAMSVSILILTSCSTTYTQSASNQKEEVKTSQKATI
                     TLQENGQNFSEKEVFFKKGDDLLSILKRNFEVKEDNGFITSLEGHSQDEKNQLYWMFT
                     VDGKSATTGAKEIKLNDGQSVIFNLSKL"
     gene            14698..15633
                     /locus_tag="LLC22_001546"
     CDS             14698..15633
                     /locus_tag="LLC22_001546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631178.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation diffusion facilitator family transporter"
                     /protein_id="HBK5434828.1"
                     /translation="MENFKKSGMFSVIAALGANILVAISKFVGYAISGSAAMLNESIH
                     SIVDCSNQILLLFGDKQANKGQSELHQFGEGRAKYFFSTIVAMMLFFGGGALGVMEAF
                     EKLTHPSHEVGNPIIVIAILLFGLVIEGSSLRVAMKEIKELNTEKLSTMRFLRESRHS
                     EILIIFTEDLCAVIGLVLALAGTILTYATGIAAFDAISGLLIGFLLMGAAIFLAKEFY
                     SLIIGESVTASDLSKIKLAFERPEISRLIDIKTVHLSPTEILVAAKADIVGNKENEAY
                     SVINDIEKNMRQSLPDKKMYIYIETDKYDPNYSRK"
     gene            15766..16545
                     /locus_tag="LLC22_001547"
     CDS             15766..16545
                     /locus_tag="LLC22_001547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBK5434829.1"
                     /translation="MNKKKSAPWLQALHAVMPLCISYIPVGLACGVLLQKVGFDPLLS
                     GLLSILVFSGGAQFLVASMLTTQASFATTLLMVFFLELRYTLLGASLAGFMKKEKRTF
                     LAVFSQSLNDENYAVNYLKFSTDPSWNKRKALYVNWFSMTAWAGSNMIGNFFGSVIRV
                     DADLVHFALTAMFIFMFIMQMKSALLIFTGLFSGVLGVVFMVLFQNTFGLIAATVIAS
                     FAGFMLEKAFKKEKAKKLRDRGKDVNEPLFNFPEQEANHHD"
     gene            16538..16855
                     /locus_tag="LLC22_001548"
     CDS             16538..16855
                     /locus_tag="LLC22_001548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBK5434830.1"
                     /translation="MTKLYLLLLVVCLFIVAYIPRLFPMLYFTHRKVPSWFSDWMKYV
                     PVALFAALAFKDVFITHEHLDIAWNIKIAAMILVAGVAYKTRSMALSVLTGLASVFLL
                     SML"
     gene            17099..18709
                     /locus_tag="LLC22_001549"
     CDS             17099..18709
                     /locus_tag="LLC22_001549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5434831.1"
                     /translation="MNKKLMQGTFWLTFANLLCKVLGVVYLIPWLSMMGNNQDGMLAT
                     TLYNVGYLPYGLFLMLGTVGFPNAIAKKVAVATKEGDNAACRLIFRSTINIMFVIGIA
                     SAALMYLFAPLLAGISPIANVNNGILAIRSLCPSLIAIPILSAMRGYFQGKNDLRPYG
                     TSLIIEQAVRVIVILAGTYYLRVLTDGTILEAVLISTVASFFGGLAAIIHMYIVGRRK
                     DFFELKDFLISSRYFERENRSASVSIIRETLPFIFVGSVITIVQMIDQVTMKPLLHFF
                     RPEIADQQLEFLFSRASVNPNKLTLILISMVGTVAISSLPILSTMKKKDRIQIEKTVG
                     DSFSIALLILLPSLTGMSLLAGPLYTLFFGYDPESVGYFQMALLASLFFSLFTILSTM
                     LQSLNHHRFAIRLTVEAIILKVIFQVIGLGLVGGYGMSLSNGLAFGIVFVRGYHFMCK
                     EYRIAPLAKISNFFLKTFRSTLIMLAVCFAVFFLLNQRLSMESKSYAMIYCVAVGSIG
                     GLVFLFSQFGKNGFRMLKNVKHHSRSKE"
     gene            18866..19714
                     /locus_tag="LLC22_001550"
     CDS             18866..19714
                     /locus_tag="LLC22_001550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5434832.1"
                     /translation="MKLAVVTDSSAYLPERIKNHPDLFVIPIPLIMDGKIYNEGIDIE
                     ADEYYGLLKNSKDFPTTSQPVVGEVLGLYEELKEKGYDTILSIHLSSGISGFVNTLFA
                     MKDDISGVTVIPYDSKITSMPMGHMVEAALDLNDEGQSLDEILAHIDRIRDNTYAYLI
                     VDDLNNLVRGGRLTNGAALIGSLLKIKPILTFSEGKIVLFEKIRSSKKAFARAEEIIG
                     RRNNEIQPPVKLYVIHANNLEVAIAEKEKLQKKYPNAEIEIGHFGPVIGTHLGEKAIG
                     IAISAQ"
     gene            19945..20424
                     /locus_tag="LLC22_001551"
     CDS             19945..20424
                     /locus_tag="LLC22_001551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434833.1"
                     /translation="MEIPTNLKHKPVIVVEDYDKVDGRNALNTDAKGLSLGLAQWNDR
                     GKVDISGKVWRHTGEKWSRQSEELPITRILDLAILAAQGSLYFQDAYRYEKFYDPENP
                     VVDIIGLQGNRMTVEVDTKNPKIDEDIILYYDTLQKDGELIGERFRILKRLLDELGY"
     gene            20457..22685
                     /locus_tag="LLC22_001552"
     CDS             20457..22685
                     /locus_tag="LLC22_001552"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5434834.1"
                     /translation="MENFSLTENRTFSRLEKQMIWKKPKSHRTSAEEWRIASEIKGNW
                     QDPEMKISNVLLEGDAGSGKTQLAKALSADLQLPYTKVTCFADMDKSDVFGALLPVVD
                     SNKEQDQELLEAIYQTDTLEAVLTLIQNHYGIDPFSAKEKLAELVQRIEADYPDAIHY
                     SYYPSEIVRAIEKGYLLEIQEPTVIRDASVLVALNSALEPNGMLNLPTGIIRRHPDCV
                     IVITTNRNYQGNRPLNESLRDRMQHAEKMDLPALEVMAERAMAKTMIQKQELLLKMAE
                     IIRLLDETAKANAIKGVAGMRSYFYWANTYKQGQDLLQSIYPKVLYKLSTDSDELAIL
                     EQALSDSGLLLELQDILRKEKWGHPQSEHTKGRTISAEEANERNITENAEEILRLDEK
                     KSLSAEEPNEGEEKQEETIEKNEIPPQMQKERSSDIEGKNQKEQQTGDDSQEMSASDM
                     EAHDKEIKKQLNKEARQIMKETIHEKEGLIVHRPAFQGKTPEARELHMQVMPIVESLS
                     RQILELLDNEQTETYQKGKYEGQRFNASKVAYGDLRNFDKKNPPHEQPSLAVAVRIDE
                     SGSMIRDDRIEAAKKAAIAIAEFSKKVDIPLLIYGDTADRSSREKTSLFSYKEFEDGF
                     QWLNEKLVTMKPRQNNRDGAALRLAAEKLNRQSATTKLLLNISDGQPKALPDYTGKKA
                     KEDIQSVLKEYERQGILFVSAAIGQDKEEIKSIYGESRFVDITDLNEFPKQMIQLIAR
                     YL"
     gene            22814..24457
                     /locus_tag="LLC22_001553"
     CDS             22814..24457
                     /locus_tag="LLC22_001553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-glucosidase"
                     /protein_id="HBK5434835.1"
                     /translation="MIQEQKWWKEAVGYQIYPASFKDSNGDGQGDINGIREKLNYLKD
                     LGIGFIWINPIYQSPFVDNGYDVSDYQDIEERFGTMEDFDLLLKEAHELGIKVIMDLV
                     INHSSDQHQWFEESKKSKESPYRDYYIWVDGVDGKEPNNWTSIFGGSAWEYSHETGQY
                     YLHVFAKEQPDLNWESEKLKEELFNMIRWWLDKGIDGFRLDAISHVKKDEYSVKATEN
                     PFSPFQNVSGIEEHLTDLKHVFEEYDIMTVGEASGVTAEEGPQWVGKDGYFDMIFEFD
                     HIHIWQQEKEGQLDVLKLKLALSAWQTSLDGIGWNALYMENHDVPRAVSVFGDTRPDF
                     WAMSAKAIAMMYFFLQGTPFIYQGQEIGMTNMPFESIDQVDAVDSKRLYKRLLAEGKT
                     REEALDIIRETTRDNSRTPMQWTSEQYAGFSTHEPWLITNPNTKTINVEQQEYEPESV
                     LQFYKNMIRIRQTNKGLIYGSYKEYLHEHPQLYVYERYLEDEQYLIMVNLTESLADYE
                     LPKEADQSWTLLLSNSSSGEFEAKGILAPYEARLYKINK"
     gene            complement(24530..25075)
                     /locus_tag="LLC22_001554"
     CDS             complement(24530..25075)
                     /locus_tag="LLC22_001554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290783.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01440 family protein"
                     /protein_id="HBK5434836.1"
                     /translation="MKLSEKELKDQLTEIVNDILAEAHLKKGDLFVLGCSTSEVVGGH
                     IGKNSSAEVGQWIIRTLKELLDPKEIALAVQGCEHLNRALVVERTVAEAKNFEIVSVV
                     PALHAGGACSVAAFDQFNDPVEVEHVVGQAGIDIGDTSIGMHIKHVQVPVRPRLKTLG
                     QAHVTALRSRPKYIGGPRANY"
     gene            complement(25098..25583)
                     /locus_tag="LLC22_001555"
     CDS             complement(25098..25583)
                     /locus_tag="LLC22_001555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5434837.1"
                     /translation="MKTKQLTIYAMLIALTVALSLTILIPVPATNGFVTLCEAGIYTA
                     AFLYGPTGGLVVGASSGLLIDLISGYPQWAVFSLVIHGLQGYVAGSFSKSSTRMWGLG
                     LLLGSLVMIIGYGIAGWILYDWPAGVASIPGNIFQNLIGMGLAFPITASLQRIQARKQ
                     Y"
     gene            complement(25573..26385)
                     /locus_tag="LLC22_001556"
     CDS             complement(25573..26385)
                     /locus_tag="LLC22_001556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330524.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxymethylpyrimidine/phosphomethylpyrimidine
                     kinase"
                     /protein_id="HBK5434838.1"
                     /translation="MKRILTIGGSDPFAGGGIQTDLKTFENFGLFGLSALTSIGALDI
                     NERFMLESISLELLKRQLVSIDKMTSLDGIKIGLLNSSEAIMVVRDFIKTKQNIPIIL
                     DPVLAFKETEAVINQLYISQLIEELFPLVTMITPNLAEAALLSGQALPSSLTEMIHLA
                     KELTASGTKNIVIKGGTRMAGDEAVDLLYSIDHYEVFSHKKIDTTTVNGAGCAFSSAI
                     TANLVLGADFTKAVAESKKFVAHCISNGVLMNDHTGSVWSGGIQKGGMRNEN"
     gene            complement(26524..>27633)
                     /locus_tag="LLC22_001557"
     CDS             complement(26524..>27633)
                     /locus_tag="LLC22_001557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302023.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA synthetase"
                     /protein_id="HBK5434839.1"
                     /translation="PILYLMEQPALSVSQSFLDKNEISYMTHTSGTTGIPKLICHSAH
                     SMGWRTKWQKTVFTKISEKKLIAFHISPVHSRFNIGISSLMSMGFPMMPLANAQSSKV
                     VHMLEAHRPIALETHPNNFVQWRFTAKEHPEAFSGIRYYHSTFDAINNQTMKTFLRTS
                     MAQDAVFLQVYGQSECGPMILKAHTLESLKTSDARDMGVGLEDMTSARITDSVGNVLP
                     ENTDGHIQLLSKGRALTYYKEDARFQENVYGDWWDSGDYGFMDKHGHLFLKDRQVDLI
                     ETINSTLAIEDFLLDSLDFLAEVVIVRDKNHSPQPIIALAPDKEMDWNRWWEQVHELP
                     RLNVPIIRDFDAIPRTATMKVQRLQIEKELKSQKS"
BASE COUNT         9048 a         5026 c         5526 g         8033 t
ORIGIN      
        1 tttttcttta tattttcata ataaaagttt ggttctttaa tttttaaaca tgacagaaaa
       61 ttttttcttc gttatacttg taatagaata ctattttata acaaagggga tcgaatcaat
      121 gaaaaaaact gttatttata ctagtttatt tgcagctttg tttttagctg cttgtcaatc
      181 aaataccaat caaggcacat ctgggaatac gtcttccagt agcgaacagc gctcttcaca
      241 ggtatcggac tcctcaacaa aagcaagcac atcttcgtct agccagacaa aaagttctag
      301 tgaagcaagt actcagtcag atatcaaagt gtctgcagct cgtgcgatcg aattgttcca
      361 agataaatac ccagatactg caattactag tttggaatta gatagtgatt ggggatctta
      421 cttctacaag atagaaggtg tcgatgatca aaaagaatac gaagcaagaa ttgatgctca
      481 aaatgaaaaa atggagacag agaatccaga aactctagat cgagatgaac aaaatggtca
      541 aaagaaaaaa gaagatggtc tggatgttga taaattgatc acgattgagg aagcagcaaa
      601 aatcgccgtc gacaaagtag gaagcggtac ggcaacagat tgggatttgg ataaagattt
      661 aggtactact tattgggaag tcaaagtaaa agacggcaat caaagtacat cagtcaagat
      721 caatagccaa acaggcgaag tactgtcaac tgaacaagat gattaagaat ttcttcggaa
      781 aacaagagtt gatttttctt ttagtcatga tacactagac aaaataactt gtttgaagga
      841 gcgatttact tgagtttaga aacgaccttt gccaatcata tctttgccaa tcctttgatg
      901 aatgcatctg gtgtccactg catgactacc caggaattag atgaactggc tcattcagaa
      961 gcaggagcat ttatcactaa gagctgtacg atcaatgaac gaaaaggaaa tcccgaacca
     1021 cgctattttg atgttccttt agggagtatc aattctatgg gacttccaaa cttaggtttt
     1081 tcttattatc tagagtatgc tcttgcgtat gaaaaagtgc aggaaaacca aaatcaaccg
     1141 ttattttttt ccattgccgg gatgagtgtc caggaaaact tggaaatgct tgagaaaata
     1201 gaaaaaagtg ggtttaatgg gatcactgaa ttaaatttat cttgtcccaa tgtgcctgga
     1261 aaaccacaac tagcttacga ttttgaggcc acttatgaaa cactgaaaga agtattcagc
     1321 atcttttcta agccgctagg aatcaaattg cctccttatt ttgattttgc tcattttgat
     1381 cagatggctg atatcttgaa tcagtttcca ttgacctatg tcaatgctat caacagtgtg
     1441 ggcaatggtt tgtatatcga tacagaacaa gaagcagtag tcatcaaacc aaaagaaggg
     1501 ttcggcggca ttggcggaga gtatatcaag ccgactgctt tggcgaatgt tcgcgctttt
     1561 tatacacgtt tgaaaccaga aatccaaatc attggtacag gtgggattcg gacaggacaa
     1621 gatgcatttg aacatctgct atgtggcgca agcatgttac agattggtac cgagcttcat
     1681 aaagaagggc cggaaatttt ttctagaatc ataaaagaat taacgcagat tatgtcagaa
     1741 aaaggatata cgtcaattga cgaatttaaa ggcaaattac gcaccatttc atagcaaaga
     1801 gacgaaggtc atgattgatc ttcgtctttt tttataaaaa acactcgtct gttcattcct
     1861 gtgcaagcgt actcattgta tgttagacga acttgtggga aaataacaga ggcaaaaagg
     1921 aggataatat gaatgatgca acagaattag caaaagagct taaagaaaaa gaatttagtt
     1981 ttcaagaact agttacggat atacagaaaa aaataaagaa gcaaaatcat gaattgaatg
     2041 cgtttgtcgc gcttgaacca ttcgagagta attcccacga gctattgatt ccccagtcag
     2101 aaaaagggcc attggctggt atcccatttc ctttaaaaat gctcggtcaa gaaaaaaagg
     2161 gatggctagc tacttcagga tctcgtttat ttgaaacaca ccgagcttct catacatcta
     2221 attatgtgcg gcaagcagaa gcgataggtc tagttccttt tggacaaacc aatgcgccag
     2281 agtttggttt caaaaatatt acagacccag tcatctatgg cccagcaaga aacccttgga
     2341 accttgaatg tacaccgggc ggatcaagtg gaggagctgc tgctgcagtt tcatcaggaa
     2401 tcgttccttt agctggtgct agtgatggcg gtggttctat tagaataccc gcttcgtttt
     2461 gcggattgat tgggctgaaa ccttcgcgag ggacgatgcc agttggtcca tatgcttgga
     2521 gaggatggca aggagctgct attgatttcg gcttgacagt ttctatgaga gacacggagg
     2581 ctttatttta tgggatgaga agtatccatt ccggtgcgcc atatcaagta tcgccagttg
     2641 agtggcaaac acatccaaga aaaaaacggt tgaagatagc tttttgtgtt gattcaccga
     2701 tccactcaca gattagtgaa gaggcagtac ttgctgtaaa aaaagctgta gatttccttg
     2761 gaaaagaagg gcatgatttg acagagattc cttacccact agatggtcgt aaactgatca
     2821 cgtcttatta tcagatgaat ggcgcagaaa cagcagcaat gatccgctcg attgaaacag
     2881 gcatccagcg agctgtcaga aaagaagaac ttgaacccat ttcttggact ttgttccaat
     2941 atggtcagaa gctctctgcc gctacttaca tcgattctct gcatgtatgg gatgaagcag
     3001 caattgtcat ggaaaaccta catcaagaat acgatctatt cctttcacca acgactgcat
     3061 ttaccgcccc taaaatcagc gaagatttgc aaagtgatgc gataagagca cagatggaac
     3121 acatcagtga ttgttctgaa gtagaaggtt tagacgttgt ttcttccatg tttgaggaga
     3181 gcttgaagat cacaccttat acacagttgg ctaatctgac tggacaacca gcaatcagct
     3241 tgcctactca tttgacaaaa gaaaacatgc ctctaggaat ccaatttatg gctgccagag
     3301 gaagagaaga tttgctattt caaatcggct atctatttga agcaaatcat cagttccatt
     3361 taccaaatcc atggaaatag cagaaacaag gagaagaaga atgaagaaaa aaagattgtt
     3421 tgctctaata actagtgcct tttttatttt aagcgcttgc ggtacagctg ccgctaatca
     3481 ggaagataac agctggagta atgtagaaaa aaagaaagaa ttagtagtag cgacttctgg
     3541 cacactgttt cccgcatctt attataatga tcaaaatgaa ttagttggtt atgatgtaga
     3601 tttggcaaaa gaggtggcta aacggttaaa tgtcaaaatc tcctttaaag aatacaacgt
     3661 ggatggacaa atcacttctg tttcaaaaag agaatcagat tttgctgcga acgattttgg
     3721 tatcacaaaa gaaagagaaa aaaaattctc cctttcagag actttcaaat attcatttga
     3781 cagtatgatc gtacgaaaaa aagatgattc aggaatccac tcacttgaag atcttaaagg
     3841 gaaaaaagca gctggcgaac ccaatactag ctatatgcgt ttagcggaaa aacacggagc
     3901 taaattagtc acatatgaca atgccacgaa tgatcagtat ttaagcgatg tagcaaatgg
     3961 tcgaacagat gttattctaa atgattatta tctgcagaaa atggccgtat ctgctttacc
     4021 agatatccct gtaaaaatac tggagaacgt ttatttcaat gaaaacgaaa gtggtttttt
     4081 attgaaagaa ggaaatgatg ctctgaaaaa gaaaatcgat ggcgtattaa aagagatgaa
     4141 agaagatggg acgacaaaga aaatatctga aaaatatttt caaactgatg tttcagtcaa
     4201 accgaaagaa acgatggctg agtcggtgag tgagtgatgt actttcctct aattgatttt
     4261 tccctcatgt ggacttcact tcctttcgta ctgcaaggct tggtatacac attagggatt
     4321 ggcttcgtgt cgtttctttt aggaaatctg gtagggttgc ttttgacagt tttaggtctt
     4381 ttggattggc tgcctctgaa tgtatttatt cgtttttatt tatcgttctt tagaggcatt
     4441 cccgcactag tcctgctgtt tctgttatat tttgggttac cttatcaatt aagtgcctta
     4501 acggcttcag tcatctgctt tacgattacc agcagtgcat ttattggtga aatctatcga
     4561 ggatcactag caggcgtttc ttcaggtcag tgggacgctg gtttagcttc tggtttttct
     4621 ttctttgggg tattgaaata tatcgttttg ccgcaagctt ttcgaatctc agtaccggca
     4681 ctcagtaacg tagctatgga tctagtgaaa ggtacttcgt tagcagcaac aatcacagtg
     4741 ccagaaatat ttcaaaaagc aaagatcata ggcggtcgga cattcgatta tttttctctc
     4801 tatattttag ttgcactgat ttattgggtc atttgtatcg ggatcgaaaa agtgcaacag
     4861 tatttagaaa aacgttctat gcatcagtca atctgaaaaa tagaaatggt gctagcgtgg
     4921 ctggcaccat ttctattttt tgtttcttgt atattctgcc tagtatttta aaaccatttc
     4981 atgtaaaatg taaatcgaaa atatgttcgg aggtagaaaa catgaagacc ccgctaacca
     5041 tcgaaataga atcctcgtta taccaatatt gcatcgagca aggcggcttg gttgtagaag
     5101 aagtcacgat gcctgatgac caaggaattg tagatacgct tagctgcttg acaaaatttg
     5161 atggaagccg agaatggcga tgctatgagc tgaaagtgac aaaagcagat tttcgctcta
     5221 cagccaaact gtcatttgtt ggacattata attattttgt tttaccaagt aaactatatg
     5281 aagaagtaaa aactgaaatc cctacaggaa taggtgtttt agtgtatcgt ccgtacacgg
     5341 ttgaagagga gatgcctgcc tctggtacat ttctgattgc gaaaaaagca gcaaagaaag
     5401 agcttgctgt accggaagaa gctttgacaa accgcttcat ggcttcttta ttcagggaag
     5461 taagaaaagc aaagcaaatg gagcgaggcg taaaatattt tccaacagat caattgtaca
     5521 aagaattgaa aagacgttca gaaaatcaag atccattttc taacgaacga tattatgaac
     5581 ggtttttaga ggaaatagct agtcaggcaa tcaatgagtt gcaagaagaa gttatcgcgc
     5641 ttcagcatga ttatgaatat ttgaggcaac aacagcagat ccgtcggttg cctacagagc
     5701 cattggagtg aaaaatatgt actatcctta tttaagagga aaacaatttg acctattagc
     5761 attaaaagaa gcactgtcgc gaggattgct ctccaataaa atccaaccag tgatcgaacc
     5821 agtacgtgat tccgctacgc ttaaaaatgt gatcgaatta tttcaaaaaa agcaccatcg
     5881 aatcgctgtg atccaaaatc cccaagtagg acaattcaaa ttattcgatc agcatgtgca
     5941 cagttggaca gtcaaagaaa atagctctgt cgtccctgca cagatcttaa cgccagaaaa
     6001 tctcagtgaa gtactggatt cacctccagc gtttcttgtt ttcgatggac agcactaccc
     6061 aaaagataca gaggtgtgga aacagttggc aggagttgat tcgaaatttt tgataccaga
     6121 tactagtcgc tttcgcatct ggctgcccga aaacaaaatt gtgatccgtg actcttttca
     6181 aacgagaaag catgttgaaa gttatgcaga taaaacagat gactttttta gtgatgacta
     6241 tctttttttc cacgcagacg gatatattgg attttctgat ttcacgatcg aaggtagccg
     6301 ttatttcgat aaagggttcc ctagccgagc gcttgctatc catctaacgt atattgatgc
     6361 ttacggcaat atacgcgtga aacattttgt ctctgacagt aacgactctg ctaaagacca
     6421 agcattgaag tttcttgaag caggagataa aatgaaaaaa tggatcatgc gtcaccatca
     6481 tcaactcttg attacttcag gaatgattga attattggct ctttaccagc aacaaaaatt
     6541 ccctggactg ggagtgttga aaaagtggtc acttatgcat catttggaac ttattagtca
     6601 cctgctagat catccaaaag attggcttaa atattattca aaagttcagg aactatatga
     6661 agtgatccaa tgattagata atgtaaatga aaaaggaata gaaaagagga aactggatgt
     6721 atattcggca aacaaggaaa gaagaagtag aagaagtggt agaaatcatt aatgccgcag
     6781 cggatttcat tgcttcgcaa ggctctcctc aatggcaaaa cgggcagaaa ccaacaaaag
     6841 aaacgatttt gaacgatatt gaaagaaaag aaagctatgt attaatagtg gaagatcaaa
     6901 ttgctggaac agctgcatta gtctcaagcg tggatcccgt ttacacaaaa atagatggta
     6961 gttggaaaga atcaactggt ccttatttat cgattcatcg tgtcgcttta gcagaaagta
     7021 ctcgaggaaa aaaactagca aaaccgttct tagaacattt gttgacgatt gcagccagca
     7081 aaaatatcca agatatccgt atcgatactt atccagctaa tgaaccgatg gaaaagacca
     7141 tctattctgc tggattcact tatcaaggga tgattgaatt tccttttgaa cacggcgaaa
     7201 gaaaagcata tcaaataatc atcaattgac tataaaatca tctgagcaaa gataaagaca
     7261 ttaacactac tgaaaaaaac aatcatatga tagccaagag gttgtaacag aagtggccag
     7321 cttcaaaaaa caagaaagaa tttccgaaaa tgcttctcaa atttttgtgg aattttagcg
     7381 tattttacga aatagctgct ttctgaaact cccttcatcg agaggtcgtg acatagcttt
     7441 tgtcacgacc tctcggctta tcctacgagt attattcgat acatttatat caataatcct
     7501 ttttttattt tatctgcagc ttcttggaac gctccatcgt ttgacacgac taaaagtgag
     7561 gggatagctt tcaaacgttt caactgtgct aaatcttcta cataaaccgc cagtctggct
     7621 gaaatctgtt cagatgaatc tccacgtttt ttcaggcgcg attgcaatgt ttctttagag
     7681 atcgtaataa agataggacg gactaccgtc ccgaaatact catataaatg ccaaaaacca
     7741 tttgctgtca aaacggcgta acaatttcct actgtcagtt tctttttaat ttctgcttta
     7801 ctggaaccat atttatgttg agcatattgg tcccactctg caaactcatt tcccttgatc
     7861 atctgattga atgtattgtc agaaacaaaa taataatcct cttgatcttt ttccccaggt
     7921 cttggtgatc gattcgtgta agtaatgatc ttttgttccg gctgaaaaat agcttctgcg
     7981 agtgaagttt ttccagaacc agaaggaccg ataaatacat agcaataatt cattgtcatt
     8041 tctcctttga tgattgaaca agtgaaaaag ctttggaaaa tatttccaaa gcttttaaaa
     8101 gtaactttgc ttttttgtat attataccag caagccagtc acaatagcac ttaaaaagct
     8161 gactaaagtc gctgttagca aaattttcaa tccgtgtttt gcgacaagat ttcctttttc
     8221 ttcatttaat cccttcatcg caccagaaat gatcccgata gaagagaagt tggcaaatga
     8281 aacgaggaag acagatataa ttgctgttgt acgctcagta aaatggaaat taccatttgc
     8341 taattctgtc atagcaacaa attcatttgt aaccagttta gtcgccatga tactaccggc
     8401 atccactgct tctttccatg ggattccgct gatgaaggca agaggggcaa agatgtaacc
     8461 taggatctct tggaaagtga tgccgaatat cccgtggaag atagcattga tcatggcaat
     8521 caaagcaaca aaaccgataa gcatagcagc aaccgtgatc gccacatgga aaccatcaag
     8581 aatgtattct cccaacattt ggaaaaatgt ctgttctttg ttttcttcaa tgatcagctc
     8641 atcttctttt tcttctaata catagggatt tacaattgaa gccagaatat aaccgccaaa
     8701 taagttcaaa acaagggcag tgatcacata tttagaatcg atcagtgcca tataagatcc
     8761 gacgatcgac atagaaactg tagacatagc cgatacactc atggtgaaca aacgtttctc
     8821 agataggaag ggtaattcct tttttatgga aataaaaact tccgattgtc ctaaaatagc
     8881 agaagctact ccattataag attccaattt gcccatcccg ttgattttac ttaatcctag
     8941 accaacagct ttcataaata atggaagaat cttgatatag cgtagaatac cgataatagc
     9001 agaaataaat acaattggca tcaatacgga aagaaagaaa ggtgcacttc ctttatttgc
     9061 tacaccggca aaaacaaagt caacaccttg cccagcaaaa gcaagaagat gatcaaacat
     9121 ttttgccaat acagaaacaa ccgctgtacc aaaagttgta cgtaataata cgaaaccaag
     9181 aacaagctgt aaaacgaaca tcacaattag tggtttcaat ttgattgctt ttttgttact
     9241 gctgatcaaa aaagcaagcc ctaatgtgac aaataaacca ataataccta ataaataact
     9301 caaataatca ctcctattcc aaattccgtt ttattttacc tgttttgcaa ataaaatact
     9361 aatctttagt gaaattttca ttactttttt agagtgaaac gcattcattt tccattagaa
     9421 aataaagcga acaaaataaa aggtttaaaa agtgtaacgt cttagtaaag tctataaaaa
     9481 aacgaaacta tcgattaagc taatagtttc gttttcaaca tttataagta aactttttct
     9541 attggtaata tagattttcg gaagggtaga caggtgcgca ggtaatatcg attcctagtt
     9601 ttttcaatgt ttgttcatca tttttattga ccatcacagt agagtgggct tgtgctccct
     9661 caagttcagc tagtttatca taagcaactt gagcgattgg attcgttact gcactgattg
     9721 ataaagcgat caagacttca ttgatgctta gtgcatccaa agaggaatga agtgtctttg
     9781 atttcaatcc ttgtattgtt tcaagaacta atggtgacaa taaaggaatg tcatctgcga
     9841 tatgggctaa atgttttact gcatttaaga taactgccgc tgacgcatcc atcaatgaac
     9901 ttgtacgccc ggtaatgatg acttcatctg gtaattcgat tgcaatcaca gcagaaggat
     9961 cttttgtagg actttgcgct tgaatcttat ctgcatagtc atgggcaggg actaccacgt
    10021 ttcggtcttc aggacgtaaa ccgacttctt ccataatcag tttgattcga ttaactgctt
    10081 cttcgtcgat caatcctttt ttgaagtcgc attctgtttg gaaataacga cggatgattt
    10141 cttgtttaga ggcttcttgg acaacggtat catccacgat cccaaatcct acacgattca
    10201 cacccatgtc agtaggagat tgataaacag attctttacc agtaattttt tcaataatac
    10261 gtttgattac aggaaatgtc tcaacatccc gattatagtt cacagctact ttattgtagg
    10321 catcaaagtg gaaggaatcg atcatattga catcttttag atcgactgtg gctgcttcat
    10381 aagcaatgtt cagcggatgt ttcaacggaa cattccatac tgggaaagtt tcgaacttgg
    10441 agtaaccagc tgcatgtcct ttttggcttt catgatacag ttggttcaag gaagtagcga
    10501 gctttccact tcctgggcca ggagctgtca ctacaacgat tggtttagtt gtttcaatat
    10561 actcattttt tccaaaacca tcttctgaga cgattttttc tacgttgact ggatagtctt
    10621 cgatttctga gtgtttatag accttgatgt ttcgtctttc tagtttattg ataaagactt
    10681 tcgtggcagg ctgtccacta tagcgagtga taacgacact gttgattaat aagccataac
    10741 cacgtaattc atcgattaac cgcaagatat ccatatcata agtaatccca taatcaccac
    10801 ggatcttatt acgttcaata tctccagcat agacgcaaat cagtatttca gcttgatctt
    10861 tcaatttttg cagcaatttg attttcgcat cttcttcaaa tcctggaagt acacgtttcg
    10921 catgcttgtc gtcaactagc ttcccaccaa attctaaata taatttgtca tagtggttca
    10981 ctcgttccaa aatatacgct gactgctctt caatatattt ttctgaatca aaaccaattt
    11041 ttttcactag gttccctcct taagtactaa agcatttttt catttttttg aggattcgtc
    11101 aactggaaga gcgaaattcc tcaaaaaaac aaagaaaatg gtttaaacca acttgtctag
    11161 atagttattc attggtatga tagtttttga taaggaaggt gctacatgaa aaaaagacag
    11221 aaaaagaaaa acgcatataa acactatatc cgttcgattt ttaccggtta tgaaagaatg
    11281 cttgaagatc ccgaattgga acaattgacg tttacttatc taaacgaaga aacgcagcta
    11341 actcgtgatg agcatcagcg cattcatttc acaacaagag atctgcctag taaataaaaa
    11401 ataagataaa ggtcatcgga ttcgattctg tcctatcaga tggaaagact agttgatcga
    11461 aaaaaaggct gtaccaaatt ttggtgcagc ctgttttatg gagcattgcc cgctcttttt
    11521 tataacaatt ttttacagaa aatggtacta ttgaagtatt aataagtgaa aaacagatga
    11581 gtaagaggag gcaagtagta tgaaagagcc agatacaaat gcaaattatg agccagacga
    11641 actagaggag acgaatgcgg atcaggatac aggacaagaa tcgtcttctt tttacgatat
    11701 caaagaaaaa gcaagcatga atctttccca attattagaa gacttacagg cttttgaaaa
    11761 agctgtccgc gaagaagata tccctgagat ctaccgttta tacaatggcc gattgaatga
    11821 agaattaaaa agaagctcaa atgaaaatca cgagatcgat caattgctga tgcgtaagat
    11881 ccatgatcgt tttttacagg aatttccttt tatggaacaa gtagaaaaca tctcgccaac
    11941 gatgagctat tacaaaatcg gcacttatta ccatgatcgg cccacggtcg gtattgatgc
    12001 aagtctgcca gaaatttttg ttttgcctaa gatcgatgaa gagtgggaga aatattccca
    12061 accggagtca acggactatg acaaaaaaat caatgagcta gacgcaaagg tgatcactgc
    12121 tcagacagaa attgaacgtt tagatgaaca aataaaagaa atcaatcgac aaatgactga
    12181 tttgaacgac aataaaggat tcttgaatcg taaaaaaatc gaggaagaaa ttcaagaatt
    12241 agagaagaag aagcaagtac tatctaatga aaaattaggc tggcttcctt atattgagac
    12301 gcctgaaaca atccagcagc aaaaagaagc attgaagcaa gaagcaagag cagaccagct
    12361 tcgtgcagcc atcgtagaaa aagaacaaag gcaaatcaga cgctatttcg gtagcaaaga
    12421 gggattcggt caagcaatcc atgaattctt gatgaattat cttggcaatg agaatcctaa
    12481 taatcaatct aatgaaggag gttccgagta tgaatgaaca cgatgaagca gaatggacaa
    12541 aaaatgaaga acaaacagaa gatcatgaag aaacgaacac ttcattggaa gaacaaacaa
    12601 gtaatcctct ggatgacaca gaagaaatcc ctatgctaga ggaaacaaaa atacacgaaa
    12661 aagaaaaagt aactccgacg aatacgaata ctgcagaaaa cacccatgct tacgaaataa
    12721 ctgaaaatcc cgggtattta gaaggaaaag agcaagatca tcaagatatc gtcagtttga
    12781 ttgaaacagc ggaagcagaa ttagcggatt tacgtatgag aaaagatttg atcgaatcag
    12841 attttccaca attattagaa tcatatgatc gttttatatt gaatgaagaa ccaatctcca
    12901 cgatcggaaa gacaagcctg atcgaatact tcacgtatga attactgaaa ccgttgaatg
    12961 atattggtct ggaacggtca aattcagctt atgacacatg gaaaacaaga catttttcga
    13021 tcaattatac gttgaatgga caaaacgaat tagtcttttc ctttgtatta ccgaccatcg
    13081 atcaacgata ccaagtggaa tcgatgagtc tcctaaacgt atcaccagag acaatggaaa
    13141 tcaatgtcca agatgaccgg gtgctttctt tgatccgaca ctggtcagtg gatcgagtat
    13201 tctctgcagg gcagatcacg atattcaatc acaaattgaa tcaattatta gcccatgcaa
    13261 gaacacttgg ttttaccgtt aatcagacat tactagacaa tacgaagcca cttcgtttga
    13321 atcttcagag cgaatttgaa ttgacgaatg aagtattgga tgatattttt atcgtggcaa
    13381 tgaaaaatcc atcctacgat atggaaaaga tcaacgaaac tacttatcaa gtacgattag
    13441 ataaaggaca gtctttaacg ataacaacaa acgaaaaaga tcaaacagtc ttgtcgatct
    13501 catctggaga ctacccacga tctgtcattg atttctttat caattacgaa ttcttggtcc
    13561 cattaatggt gagaaagtcc tgattggata agttggatta ccagatgtca ttcagataat
    13621 tctgttccaa aggacttgcg gcagttatcc agaataattg tcacaagtct tttctgtatg
    13681 tactaaatgg acgtgaataa cttgctgatg aaggagggat ttcattagga atgtccacaa
    13741 ataaaatagc acagcttagc ttattgtctg ctgcttgtgt agcaggtagg atcgcttttc
    13801 aatttattcc gaatttccag ccaatgactg ctattttttt atttatagta ctttacttaa
    13861 gcttaaaaga tgcgttaatt gtcatgagtc tttctattgc gatcagcagt ttttattttg
    13921 gtgttggacc atgggtcatc ggccaatgga tcagctatac tgttgttctg agtttgtttt
    13981 caatcgtctg cttgagaaaa acagtgcaaa ggaatctatg gttaaaggga gtctgttttt
    14041 ttctggcggg catggtttac ggaataggta tgaccgtttt tgatacgctg ttatatcgtt
    14101 tgcctcaacc ttggatctat taccttcaag gggtgtcgtt tgatttgatg cacagtatag
    14161 gcaatgttgt gttctttctt gtttttctgc cagtcgtcaa acgtttttac aatcattcag
    14221 gaggaaaaaa tgaaaaaaat aatttatagt ttgcttgcaa tgagtgtcag tatactcatt
    14281 ttgacaagtt gcagtacaac ctatacacaa tcggcttcca accaaaagga ggaagtaaaa
    14341 acatcgcaaa aagcaacaat cacgttacaa gaaaatggtc aaaacttttc ggaaaaagaa
    14401 gtgttcttca aaaaaggcga tgatttactg agtattttga aacgaaattt tgaagtcaaa
    14461 gaagataacg gcttcatcac ttcgcttgaa gggcactcac aggatgagaa aaatcaactc
    14521 tattggatgt ttactgtgga cgggaaaagt gctactactg gtgccaaaga gatcaaattg
    14581 aatgatggac aatcggtcat tttcaatttg tctaaactat aagtttcata aaaaactgtt
    14641 aaagggcgaa tattgccata attcagtgag ttcagttgat gaaagaagga aaataacatg
    14701 gaaaatttta aaaaaagcgg aatgttttcc gtaattgctg ctctaggggc taatattcta
    14761 gttgctatca gcaaatttgt cggctatgca atcagtggca gtgccgccat gctaaacgaa
    14821 agcatccaca gtatcgttga ttgcagcaat cagattttgc tgttattcgg tgataaacaa
    14881 gccaataaag gacagagcga gttgcatcaa tttggtgaag gacgagcaaa atactttttc
    14941 agtacaatcg tcgcaatgat gcttttcttc ggcggtgggg cacttggggt gatggaagct
    15001 tttgaaaagt tgacgcatcc atcccatgaa gtgggtaatc cgatcattgt tatagcaata
    15061 ctgttatttg gtttggtaat cgaaggaagt tcgttacgcg tggcaatgaa agaaatcaaa
    15121 gaattgaata ctgaaaaact ttccacgatg cgctttttgc gcgaaagtcg acacagtgaa
    15181 atactgatta tttttacgga agacttgtgt gctgtaatcg gtttggtctt ggctttagca
    15241 ggaacaatat tgacttatgc aaccgggatt gctgcatttg atgcgatcag cggattgctg
    15301 atcggtttct tgctgatggg agccgccatt ttcctagcaa aagaatttta tagtctgatc
    15361 atcggtgaaa gcgtgacagc aagcgattta tcaaaaatca agttagcttt tgaacgtcct
    15421 gagatcagtc ggctgatcga tataaaaaca gttcatttaa gtccaacgga gattttagtt
    15481 gcagcaaaag cagatatcgt tggtaacaaa gagaatgaag cttactcggt catcaatgat
    15541 attgaaaaaa atatgcgtca gtctcttcct gacaagaaga tgtatatata cattgaaaca
    15601 gataaatatg acccaaatta ttctcgtaaa taaaacgttt attcatgaat tgaagcaaaa
    15661 atgagaaaaa tataatcttg tttttaaata aaacggctac aatttagcga atttatgtta
    15721 caatgagtcc gctgtttatt tgttgtaatt aaaggagata ttttaatgaa caaaaagaaa
    15781 agtgcgccat ggcttcaagc tttgcatgca gtgatgccac tttgtataag ctatatacca
    15841 gtaggattag cttgcggagt attgttgcaa aaagttggat ttgatcctct cttatcagga
    15901 ctgttatcga ttctggtctt ttccggtggc gcgcagtttt tagttgcatc tatgcttacg
    15961 acgcaagcat catttgcaac gacattattg atggttttct ttttagaatt acgctataca
    16021 ttattaggag caagtcttgc cggttttatg aaaaaagaaa agcggacgtt tttggctgtc
    16081 ttttctcaat cactgaatga tgaaaactat gcggtgaact acttaaagtt ttcaactgac
    16141 ccttcctgga ataaaagaaa ggctttatat gtcaattggt tctcaatgac tgcatgggcc
    16201 ggtagcaata tgatcggtaa ttttttcggc tcggtgattc gagtagatgc tgaccttgtc
    16261 cattttgctt tgacggccat gttcattttc atgtttatca tgcagatgaa aagcgcacta
    16321 ctgatcttta caggtttatt ctcaggcgta ttaggggtcg tattcatggt attattccaa
    16381 aatactttcg gattgattgc agcaacagtc attgcttcat ttgccggatt tatgctggag
    16441 aaggcattca aaaaagaaaa agctaagaaa ctaagagacc gcggtaaaga tgtcaatgag
    16501 ccgctcttca acttcccgga acaggaggcc aatcaccatg actaaactat atttgctact
    16561 tttagttgtt tgtctgttca tcgtggcata tatcccgcgc ttgttcccga tgctttattt
    16621 tactcatcga aaagtgccat cctggttcag tgactggatg aaatatgtac cggtggcatt
    16681 atttgcggcg ttagctttta aagatgtttt cattactcat gaacatctgg atattgcttg
    16741 gaatatcaaa atagctgcaa tgattctagt agcaggcgtg gcttacaaaa cacgttcgat
    16801 ggcgttgtca gttttgacag gacttgcgtc tgtctttttg ctgtctatgc tttaaactgt
    16861 tttattttat taaaaacaga gattgcgaca taagttgttc aaactgatct atccgaactg
    16921 catttgcaac agtcaattct ggatgcaagt ttattcgtag ggataaaaaa gattagtgtt
    16981 ggcttatgat gcaagctctt ttttatttta ggaattagag agggatttgt ccttctatga
    17041 ttttttgcta taatagggaa gatgtttatt ttatgaaaga atagttgagg gaatttaaat
    17101 gaataaaaaa ttgatgcaag gaacattttg gctaaccttt gctaatcttc tatgtaaagt
    17161 tttaggggta gtctatttga ttccctggct aagtatgatg gggaacaatc aagatggtat
    17221 gcttgctacg acattgtata atgttggcta tcttccttat ggattgttcc tgatgcttgg
    17281 tacagtcgga tttccaaatg cgattgcaaa aaaagtagct gtagccacaa aagaaggaga
    17341 taacgctgct tgtcggctga tttttagaag tacgatcaat atcatgtttg tcatcggtat
    17401 cgcctctgct gcactgatgt atttatttgc tcctttacta gccggaatca gtccgattgc
    17461 taacgttaat aatgggatac tagctatcag aagtttatgc ccatctttga ttgctatccc
    17521 aattcttagt gcaatgagag gatatttcca aggaaaaaat gatctgcggc cttatggaac
    17581 ttctttgatt atcgaacagg ctgtgcgagt gatcgttatc ttggctggta cttattactt
    17641 gcgcgtattg actgacggaa ccatattaga agctgtattg atcagtacag tcgcttcttt
    17701 cttcggtggg ttagctgcga ttatccatat gtatatcgtc ggacgcagaa aagacttctt
    17761 cgaacttaaa gattttttga tttccagccg ttatttcgaa agagaaaacc gatctgcctc
    17821 tgtctctatc attcgggaaa cactaccgtt tatttttgtc ggctcagtca ttactatcgt
    17881 tcaaatgatc gaccaagtaa cgatgaaacc actgcttcac tttttccgtc cagagatcgc
    17941 agatcagcaa ctggaattct tattcagccg tgcttctgtc aatccaaata aattgacatt
    18001 gatcctgatc tccatggtag gaacagtagc tataagcagc ttgccaatat taagcacgat
    18061 gaagaaaaaa gatcggatac aaatcgaaaa aacagtagga gatagttttt cgattgcgtt
    18121 attgattctt cttccttcat tgactggaat gtctttatta gctggaccac tatacacatt
    18181 gttttttggc tatgatcctg aaagtgtcgg atatttccaa atggctttgc tagcttcttt
    18241 gtttttctct ttattcacga tcctatctac gatgcttcaa tctttgaatc accatcgttt
    18301 tgcgatccga ttaactgtag aagcaattat cctgaaagtc atcttccaag taatcggatt
    18361 aggattagtt ggcggatacg ggatgagctt atcaaatggc ttagcattcg gtattgtctt
    18421 tgttcgcggc tatcacttta tgtgcaaaga ataccgaata gcacctttag caaagatcag
    18481 caattttttc ttaaaaactt tccgctccac cctgattatg cttgcagtat gttttgccgt
    18541 tttctttttg ctgaatcagc gattgtcaat ggaatcaaaa agctatgcaa tgatttattg
    18601 tgtggctgta ggaagtattg gcggcttagt atttttattt tctcaattcg gaaaaaatgg
    18661 gtttcgaatg ttgaaaaatg ttaaacatca tagcagaagc aaagaatagg ttaactaatc
    18721 gttttttgct gtcacttgaa aaacggcaac tcgtatgatt acgcttgtcg tttttctatt
    18781 ttccaatttt agtttcatat ctaatcttac ttatgatata gttataaggt ctggaaaaat
    18841 tctttgaaac gaggaaatta aacacatgaa acttgcagta gttacagata gttcggcata
    18901 tctgccggaa cgtatcaaga accatcccga cttattcgtt attccaatcc ctttgattat
    18961 ggatgggaaa atttataacg aaggaatcga tatcgaagcg gatgaatatt atggactttt
    19021 aaaaaacagt aaagattttc ctactacttc acaacctgtc gtaggggaag ttttgggttt
    19081 atatgaggaa ttgaaagaga aagggtatga cacgatttta agtatccatc tttcttcagg
    19141 gatttctggc tttgtcaaca cattatttgc gatgaaagat gacatcagcg gagtaacggt
    19201 cattccttat gactctaaga tcactagtat gccgatggga cacatggtag aagctgcctt
    19261 agacttaaat gatgaaggtc agtcccttga tgaaatactt gcacatatcg atcgaatccg
    19321 agataatacc tacgcttatc tgattgtaga tgatttgaac aatttagtac gaggaggacg
    19381 tttgacaaat ggtgcagcgc tgattggcag cttattaaaa atcaaaccga tcctgacatt
    19441 ttctgaaggg aaaattgttt tattcgaaaa aatccgttca agtaaaaaag catttgctcg
    19501 agctgaagaa attattggta gaagaaataa cgaaatacaa ccgccagtca aactttacgt
    19561 gatacatgca aataatttag aagtagcgat tgcggagaaa gagaaattgc agaaaaaata
    19621 tccaaatgca gaaatcgaaa ttggtcattt cggaccagtc attggtacac atttaggtga
    19681 aaaagccatc ggcattgcca tttcagcgca ataattcctt ttattcaaaa aacataccaa
    19741 aaatattcca acatcatctt ggactttcta catgttacta atgagcgtgt aaaagaacga
    19801 gatggtgttt ttatttctat caatgaagct ctttttcttt gcaatcctca cttcaatcct
    19861 ctataatgtc gcatatagtt tagtaaatga gtaaactact aatttactta tttactaaaa
    19921 ataaaaggat gaggagttaa aataatggaa ataccaacaa atttaaaaca taaaccagta
    19981 atcgttgtag aagactatga taaagttgat ggaagaaatg cattaaatac ggatgcaaaa
    20041 gggctttcac tgggccttgc tcagtggaat gatcgtggaa aagtcgatat ctcaggcaag
    20101 gtatggcgac atactggaga aaaatggtca cgacagtcgg aagaattacc aatcacacgt
    20161 attttagatt tagcgatctt agctgcacaa ggaagtttat acttccaaga tgcttatcgt
    20221 tatgaaaaat tttatgatcc agaaaatcca gtcgtagaca tcattggatt acaagggaac
    20281 cgaatgacgg tagaagtaga taccaaaaat ccaaagatcg atgaagacat cattttgtat
    20341 tacgatacac tacaaaaaga cggagaactg attggggaac gattccgtat tttaaaacgt
    20401 cttttagatg agctaggata ttaatagaca gagatgatca aaaggggaag agaagcatgg
    20461 agaatttctc actaacagaa aaccgaacct tttcacggct agaaaagcaa atgatctgga
    20521 agaaaccgaa aagccatcgg acaagtgcag aagaatggcg gatcgcctcc gaaatcaaag
    20581 ggaattggca agatcctgaa atgaaaatca gtaacgtact tttggaagga gatgccgggt
    20641 cggggaagac acaattagcc aaagcactat ctgctgatct gcaacttccc tatacaaaag
    20701 tgacctgttt tgcagatatg gacaaatcag atgttttcgg agccttatta cctgtagtag
    20761 attctaataa ggaacaagac caagaattac tagaagctat ttaccaaaca gatacacttg
    20821 aagctgtact gacactgatc cagaaccatt acggcattga tcctttttct gctaaagaaa
    20881 aattagcaga gctagttcaa aggatcgaag ctgattatcc agatgcaatc cattacagct
    20941 attacccttc tgaaatcgtt cgagcgattg aaaaaggata tttattagag attcaagagc
    21001 cgactgtcat ccgagatgcc tctgttcttg tggcacttaa ctcagcgctc gaaccaaatg
    21061 ggatgttgaa tttaccgaca ggaatcattc gtcgccatcc agattgcgtc attgtgatca
    21121 ctacaaatcg aaattaccaa ggaaatcgcc cattaaatga atctttaaga gatcggatgc
    21181 aacatgcgga aaaaatggat cttcctgcct tagaagtcat ggcagaacgt gcgatggcga
    21241 aaactatgat ccaaaaacaa gaacttctct taaagatggc agagattatc cgtttgttgg
    21301 atgaaactgc aaaagctaac gccatcaaag gtgtagcagg aatgcgttct tatttttatt
    21361 gggcaaatac ctataagcaa ggacaagatt tactccagtc gatttatcca aaagttttgt
    21421 ataaattatc cactgattca gatgaattgg caattcttga acaagctttg tctgacagtg
    21481 gattgctact ggaacttcag gacatattga gaaaagaaaa atggggtcat cctcaatctg
    21541 agcatacaaa aggaagaacc attagcgccg aagaagcaaa tgaacgaaac atcactgaaa
    21601 atgctgaaga aattctgcgc ttagatgaaa agaaatcgtt gtctgctgaa gaaccaaatg
    21661 agggagaaga gaaacaagaa gaaacaatag aaaaaaacga gattcctcct caaatgcaaa
    21721 aagaacgcag tagcgatatc gaaggaaaaa atcaaaaaga acaacaaaca ggagatgatt
    21781 ctcaagaaat gtctgcttct gacatggaag cacatgataa ggaaatcaag aagcaactga
    21841 ataaagaagc gcgacaaatc atgaaggaaa cgattcatga aaaagaaggt ctcatcgttc
    21901 accgaccagc tttccaagga aaaacgccgg aagcacgtga gctacacatg caagtaatgc
    21961 caatagtaga atcacttagc cggcaaattt tagagttact ggataatgaa caaacagaga
    22021 cgtaccaaaa aggaaaatac gaaggtcagc ggttcaatgc aagcaaagta gcatatggtg
    22081 atttgagaaa ttttgacaaa aagaacccgc cacatgagca accttcttta gcggtagctg
    22141 tacggatcga tgaatctggg tcaatgatac gggatgatcg gatcgaagcg gcaaaaaaag
    22201 cagcgattgc cattgccgaa ttttctaaga aagtcgatat cccattgttg atttacggag
    22261 atacagcaga ccgttcgtca agagaaaaga cttctttgtt ttcttataaa gaatttgaag
    22321 acggatttca atggttaaat gaaaaattag tcactatgaa accaaggcaa aacaatcgtg
    22381 atggtgctgc acttcgttta gcagcagaaa aattaaacag acaatccgca acaaccaaac
    22441 tgttgcttaa tattagtgac ggtcagccaa aagcgttgcc ggattataca ggcaaaaaag
    22501 caaaagaaga tatccagtct gttttgaaag aatatgaacg tcaaggaatc ctatttgtct
    22561 ccgcagctat tggccaagac aaagaagaaa tcaagtcgat ctacggtgaa agtcgttttg
    22621 tagatattac tgacttgaat gaatttccca agcaaatgat tcaactgatt gcccgctatc
    22681 tatgataaaa taaagctcaa cgaacgcact tagcagattc gttgagcttt tcgtttctag
    22741 ttaccggtaa caaggatact tctaaaatag aatcggttat aatcaagagg gaccgttaaa
    22801 ggagtgaaac gatatgatac aagaacaaaa atggtggaaa gaagcagtag gctatcaaat
    22861 ctatcctgct agtttcaaag atagcaatgg cgatggtcaa ggagacatca atgggatccg
    22921 tgaaaaactt aattatttga aagatcttgg tatcggcttt atctggatca atccgatcta
    22981 tcaatctcca tttgtcgata atggttatga cgtaagtgac tatcaagata tagaagagag
    23041 attcggaacg atggaagatt ttgatttatt gctaaaagaa gcacatgaat tagggatcaa
    23101 agtgattatg gatcttgtca tcaaccatag ttcggatcag catcaatggt ttgaagaatc
    23161 gaaaaaatct aaagaaagcc cgtatcgcga ttattacatt tgggtcgacg gggtagatgg
    23221 caaagaaccg aataattgga catcgatttt cggcggttct gcttgggagt attctcatga
    23281 aactggacag tattatctgc atgtttttgc aaaagaacaa ccagacttaa attgggaaag
    23341 cgagaaattg aaagaagaac tattcaatat gatccgatgg tggttggata aagggataga
    23401 tggatttcgt ttagatgcga tttctcatgt aaaaaaagat gaatattcag taaaagccac
    23461 agagaaccct ttctcaccct ttcaaaatgt ctcaggaatc gaagaacatt tgaccgattt
    23521 gaaacatgtt tttgaagagt acgatatcat gactgtcgga gaagcaagtg gtgtcactgc
    23581 agaagaagga ccacaatggg tagggaaaga cggttatttc gatatgatat tcgaatttga
    23641 tcatatccat atctggcagc aagaaaaaga agggcaatta gatgtcctta aattgaaact
    23701 tgcattaagc gcttggcaaa cttcattgga tggtatcgga tggaacgctt tatatatgga
    23761 aaaccatgat gttcctcgtg ccgtttcagt gtttggagat actcgtcccg atttttgggc
    23821 tatgtctgca aaagcaatcg ctatgatgta tttctttttg caaggtacgc catttattta
    23881 tcaaggacag gaaatcggaa tgacgaatat gccctttgaa tcgatcgatc aagttgatgc
    23941 agtagattcg aaaagacttt ataaaaggct gcttgcggaa ggtaagacaa gagaagaagc
    24001 attggatatc attcgtgaaa caacgagaga caacagcagg acacccatgc aatggacttc
    24061 ggaacaatat gctggttttt ctacacatga accttggctg atcactaatc caaataccaa
    24121 aacgatcaat gtagaacaac aagaatatga accagagtcg gtcctgcaat tctataagaa
    24181 catgatccgc attagacaaa ccaataaagg tctgatatac ggttcttata aagaatatct
    24241 tcatgaacat ccacaacttt atgtctatga aagatattta gaagatgaac aatatcttat
    24301 tatggtaaac ttaacagaat cacttgctga ctatgaactt ccaaaagaag cagatcagtc
    24361 ctggacatta ctcttgtcaa attcctctag cggagaattt gaagctaaag gcatactagc
    24421 accttatgaa gctcggttat ataaaataaa caagtaaaac ttcctcgtta aagttcatta
    24481 gttggacttt gcgaggaagt ttttcagatt gctctgtcaa ttactcattt caataattcg
    24541 ctctaggacc accgatatat ttaggacgag agcgaagggc tgtcacgtga gcttgtccaa
    24601 gggttttcaa acgaggtctg acaggtactt ggacatgttt gatatgcata ccgattgatg
    24661 tgtcaccgat atcgataccg gcttgtccaa ctacgtgttc cacttcgaca ggatcattga
    24721 actggtcaaa agcagcaaca gaacaagcac ctccagcatg tagtgcagga acaacagaga
    24781 caatttcgaa attttttgct tctgccactg ttcgttctac tactaatgct cggttcaaat
    24841 gttcacaacc ttggacagct agcgcaattt ctttaggatc caacaactct tttaacgtac
    24901 ggatgatcca ttgaccaact tccgcactgg aattttttcc aatatgtcct ccaacgactt
    24961 cgcttgtgct gcatcctaaa acaaaaagat cacctttttt caagtgtgcc tcagccaata
    25021 tgtcattaac tatttcagtc aattggtctt ttaattcttt ttctgacaac ttcattttct
    25081 aaaaccttct ttttcaatta atattgcttc cgtgcttgaa tacgttgaag acttgcagtt
    25141 ataggaaagg caagtcccat tccaatcaga ttttggaaga tgtttcctgg tatagaagcc
    25201 actccagccg gccaatcata taaaatccaa ccggcgatac catagccgat gatcataact
    25261 aagcttccta ataaaagccc taatccccac atacgagtag aagatttgct gaaagaacca
    25321 gcaacatatc cttgtaaccc gtggatcact aatgaaaaaa ctgcccactg cggatatcct
    25381 gaaatcaaat cgatcaatag accactggaa gcaccaacaa ctaatccacc cgttggacca
    25441 taaagaaaag cagcggtata gatcccggcc tcgcataatg tcacaaatcc attcgtagcc
    25501 ggtacaggga tcaaaattgt taatgaaagg gcaactgtca acgcaatcag catagcatag
    25561 atcgttaatt gcttagtttt catttctcat tcctcctttt tgaataccgc cagaccagac
    25621 acttccggta tgatcgttca tcagcacgcc attagaaata caatgggcaa caaatttttt
    25681 actttctgct actgctttgg taaaatctgc ccctaacaca agattcgctg ttattgcaga
    25741 agaaaaggca caaccggccc cgtttactgt tgtagtgtcg atttttttat gagaaaatac
    25801 ctcataatga tcaattgaat agagaagatc cacagcttca tctccagcca tccttgtgcc
    25861 gcctttgatc acaatgtttt ttgttcctga agcagtgagt tctttagcga gatggatcat
    25921 ttctgttaac gaagagggaa gagcttgacc agaaagtaaa gcagcttctg ccaaattagg
    25981 cgtaatcatc gtaacaagtg gaaaaagttc ttcgatgagc tgcgaaatat acaattgatt
    26041 gatcacagct tcagtttctt tgaatgccaa aacagggtct aaaatgattg ggatattttg
    26101 ttttgttttt atgaagtctc gaacaaccat gattgcttca cttgaattca ataacccaat
    26161 tttgatacca tctaatgaag tcattttatc aatcgaaact aactgtcgtt taagcaattc
    26221 caaagatata gattccagca taaatcgctc attaatatct agtgccccta tagaagtcaa
    26281 ggcgcttagt ccgaatagac caaaattctc aaaagttttt aaatctgttt ggattcctcc
    26341 accagcaaat ggatcagaac cgccaattgt caagattctt ttcataacat tttcctccat
    26401 gaataagagt ataacgaaat tttcaaaaaa gaaaaacagc caattggcat atttttatct
    26461 catccaattt aaaaaaacaa aaagaaaaga aagaccaaaa tggatctttc tttccttaaa
    26521 tagttaggac ttttgtgatt ttaattcttt ctcgatttga agccgttgca ctttcattgt
    26581 agctgttcgc gggattgcat caaaatcacg gatgataggg acgttcaagc gaggaagttc
    26641 atggacttgc tcccaccatc gattccaatc catttcttta tcaggagcta aagcaataat
    26701 cggttgtgga gaatgatttt tatcccttac aatcactact tctgccaaaa aatctaacga
    26761 atctaataaa aagtcttcaa tagctaatgt actattgatc gtttcgatca aatccacttg
    26821 ccgatctttc aaaaataggt ggccatgctt atccataaaa ccgtaatctc cgctatccca
    26881 ccaatcgcca taaacatttt cctggaaccg tgcatcttcc ttgtaataag tcaaagcccg
    26941 tcctttagac agtaattgta tatgaccatc tgtgttttca ggtaggacat tcccaactga
    27001 atctgtaatc cgagcgcttg tcatgtcttc cagtccaacg cccatatctc ttgcatcact
    27061 tgttttcaaa ctctctagtg tatgagcctt aagaatcatt ggtccgcatt cactttggcc
    27121 atatacttga agaaataccg catcctgtgc catcgacgtt cgcaaaaatg tcttcattgt
    27181 ctggttgttt atagcatcaa aagtggagtg atagtatcgg atacccgaaa aagcttctgg
    27241 atgctcctta gcagtaaaac gccactgaac aaagttattc ggatgggtct ctagtgcaat
    27301 tggccggtga gcttccaaca tatgaacaac ttttgaactt tgtgcgtttg ctaaaggcat
    27361 cataggaaat cccatggaca tcaaagaaga gataccaata ttgaatctgg aatgcactgg
    27421 agagatgtga aaagcgatta atttcttttc cgaaattttt gtgaaaactg ttttttgcca
    27481 tttcgtccgc catcccatag aatgagcaga atgacaaata agtttaggga taccagttgt
    27541 accagaagta tgggtcatat aagaaatttc atttttgtct aaaaatgatt gagaaacaga
    27601 caaagcaggt tgttccatta aataaagaat agg
//
LOCUS       DAFBVQ010000031        27311 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.031, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000031 DAFBVQ010000000
VERSION     DAFBVQ010000031.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27311)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27311)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27311
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.031"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            647..964
                     /locus_tag="LLC22_001558"
     CDS             647..964
                     /locus_tag="LLC22_001558"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBK5434840.1"
                     /translation="MLFYSNFILIVAILLLLNIWIFDRSRNSSIGFRTKRSLSSKKNW
                     VYSQTIFYGGIVLISLLSSTLYSLNIIDVSTSNSISIIGIIIAAIITQLFLVFGEKKR
                     SKK"
     gene            complement(1055..1420)
                     /locus_tag="LLC22_001559"
     CDS             complement(1055..1420)
                     /locus_tag="LLC22_001559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434841.1"
                     /translation="MIKTCWKNLPLLLSFVPYVHFALLLDFRYHSVSGFITLIFLSLF
                     AGYYFQRNRRIISLFIANIISTVTSYLFCANFTEWRYFYHPLKPTQLILLLAGIYLVP
                     QILGSLWAVALSYKKARHP"
     gene            1628..2110
                     /locus_tag="LLC22_001560"
     CDS             1628..2110
                     /locus_tag="LLC22_001560"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434842.1"
                     /translation="MRRKAVIDRLYLFFWFFPIVLLPFTWVNAVVQGAEILGLIQGSG
                     FVVSRNFPALIVFYLVISVGLLLPKSLINHYNWQLLYFSCLLVFTSMFSLLPRLIIGP
                     NGLSESGLKDLAYSSMYFLTIKPWFYLVIASFILATFFYFWTEIRIKSERSVSIKNNY
                     "
     gene            2307..3197
                     /locus_tag="LLC22_001561"
     CDS             2307..3197
                     /locus_tag="LLC22_001561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphate ABC transporter substrate-binding
                     protein PstS family protein"
                     /protein_id="HBK5434843.1"
                     /translation="MKKVLFTLGMMGILLAGCGSGSGNTDGSATQNNSSDSNEQVKIV
                     AVGSTALQPLVDAAQESFVQENPNYQISVQGGGSGTGLSQVEAGAVTIGNSDVFAEER
                     DGVDASKLVDHKVAVVGMAPIVNKDTDVKDITKQELIDIFTGKITNWKEVGGKDQKIN
                     VVNRANGSGTRATFEKWGLDGATPVQSQEQDSSGTVRQLVSQTPGAISYLAFSYLDDS
                     TQALSIDGVEPKEENVADNSWGIWSYEHMYTNGKPSPEVQKFLDYMMTEEIQEGPVKE
                     LGYLPITMMEVERDHEGNIK"
     gene            complement(3484..4758)
                     /locus_tag="LLC22_001562"
     CDS             complement(3484..4758)
                     /locus_tag="LLC22_001562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5434844.1"
                     /translation="MDNHTRKLLGLTDKHLFFDEEWLIEKEYKGVQAQFIKGKLDDSS
                     SYCEHCRSVRIIRNGSYTTRTQMLKVKEKLTILELKRTRFLCHDCGRTFSAKTDLVDE
                     HHQLTKELKQAILMELYENQSRKLIAKKYFVSDGTVTRILREATKHYQPRMNFLPTVL
                     CMDEFKSMNSVSGSMSFICVDGTTNQLFTILEDRRLYKLTQYFLRFPRKARLKVKYLV
                     MDMNASYCQLLKTVFPNAEIVTDRFHIVQHINRSFNQLRVQIMNRFRTSHSENQKKYR
                     RLKRYWKLLLKDSTTWEPLKRHYHRLFKRPISQTEIVDELLSYNEELRTAYHFCQLLR
                     YYFVKRGTEGFQETLKTISSTLPQSFKKKFTIFHCYQSGISNAFKVSHSNGVTEGLNN
                     KIKLIKRIAFGYRNFYNFRARIYLQQGLIFEN"
     gene            5031..7502
                     /locus_tag="LLC22_001563"
     CDS             5031..7502
                     /locus_tag="LLC22_001563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation-translocating P-type ATPase"
                     /protein_id="HBK5434845.1"
                     /translation="MKNKWINRSKKKKVTQRSSDKVIRLFPSYKEGLTADQVKERIEK
                     GAANNSVDPTFKTNQQIVLENIFTYFNLIFLILAILLCLVESYKNLTFLPVIIANTGI
                     AIFQEIRSKKILDELNVLNTAKVNVIRDGIEQTIDIEDLVIDDIVILETGYQIPADAE
                     VVEGKLQVNEALLTGEADEITKEIGDPLMSGSFIVSGKAYARLDKVGADSYISQLTVK
                     AKTMGEGEQSEMIASLNQLIKWIGIIIIPIGILLFSQSYFFNGNTIKESVVAMEAALI
                     GMIPEGLYLLTTIALALSATKLAKQRVLLHNMKSIETLARVNVLCVDKTGTITENKMS
                     VQKMIVSKKQEIISQSDQLEACIADYAKAMAGDNATMEAVKAYFTKTTDQSYHHVIPF
                     SSVQKFSSVALADKVYVLGAPEMVLRDQLPEYAEEFVSFAEKGYRVLVFGVYDGILEE
                     PVLTEAVTPLGYILIANPIRKEARATFDYFKKQQVAIKVISGDNPLTVSNVAVQAGIS
                     HADQYVDASKLSEEEYEAAVEKYTVFGRVKPEQKKIFVQLIKRNNTVAMTGDGVNDIL
                     AMKEADCSIAMASGNEAAMQASQVVLLDSDFSRMPEVVAEGRRVVNNIERSASLFLVK
                     NIFSFLLSLFSVIFALTYPLEPSQITLISLFTIGLPSFLLALEENKKRIRGKFIMNVM
                     EKAVPGGLTDMIVVGALVICGVTLNLNKTDVSTASTMLLIAVGFLVLYKICSPLNKFR
                     SQIILFCASGNFFSVIFLHKLFSITGISAVSLLLLSILFFSADSIFRHLTTLVEYLFE
                     RKNEKEQKPFSRVAKKFLSIFKREN"
     gene            complement(7605..9341)
                     /locus_tag="LLC22_001564"
     CDS             complement(7605..9341)
                     /locus_tag="LLC22_001564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component sensor histidine kinase"
                     /protein_id="HBK5434846.1"
                     /translation="MKWKKIYERLFFLILLVSLFFGGWQLISHYFQQQIVEQQESYLT
                     KKAQLLIRQLDVENLQAAQNKTALEEFVHQSNERITLMDATGKILFDTNNETLNEQRN
                     SRPEIKAVLNGGNLGSALRKSTTLNEDLLYVALPVKKSGQLEAILRIAEPTSVFLPRT
                     ESFRRWVFFFFLSFFLVLAGMIYYLIYQKNQPLKTVLPVLKKMVQNPNQAEVIMQTPD
                     QWEELYQTINALSEQMSKMYRACTTTEEQLYTLLNELMIGVFLIDDADSRLLLLNPKM
                     QLHLNVVSYQPEQRYTEVIQEPKLIQLIHQVTPEHPLIHQEITLTEGRQTLDLSLRYF
                     TNSEGTGQILGVAYDLTKVRRLEKLQKDFVGNVSHELKTPVTSLIGFTETLLDGAKDD
                     PQTLTSFLEIMQKDAIRLDKLIREIIQLSKDGENSYEIQTIYTEPYFQQIVQNYQPII
                     EKKRLTIRLIGKNEPFTTKTDILYPIIKNLIENAVQYSKSDSEIIIRYQATDDLSFSV
                     QDFGIGIDIEDQERIFERFYRVDKARSRHSGGTGLGLAIVKDYVQLLNGTITVDSHLG
                     TGSTFTVTIPKM"
     gene            complement(9338..10042)
                     /locus_tag="LLC22_001565"
     CDS             complement(9338..10042)
                     /locus_tag="LLC22_001565"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5434847.1"
                     /translation="MKKILVVDDEPSIVTLLTFNLEKEGYKVTSATDGGEGLELALEQ
                     SFDFIILDVMLPTMDGMEITQRLRQEKNETPILMLTAKDDQVDRIIGLEIGADDYLTK
                     PFSPREVLARMKAIFRRIEPRKQSKDEAEPEYLSIGQITADLTNYQVTVDDHLIELTP
                     KEFELLVYFMKRKDRVIDRDTLLDRIWNFDFAGQSRIVDVHVSHLREKIERDPKHPKY
                     LVTIRGFGYKFQEPKR"
     gene            10173..10676
                     /locus_tag="LLC22_001566"
     CDS             10173..10676
                     /locus_tag="LLC22_001566"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF523 domain-containing protein"
                     /protein_id="HBK5434848.1"
                     /translation="MIGISACLGGLACRYDGQKKEVPELMELVETGEAVMVCPEVIGG
                     LPIPRDPAEIIGGNGFDVWKDQAKVWTTSGEDVTEAYKNGAIKAYQKLQEKHIDLVIM
                     KEKSPSCGTHSIYDGSFSGIKKNGAGVATAYFIQQKMTVLSDEEWLKTRGEQNGNRKD
                     QSNERAL"
     gene            10636..10974
                     /locus_tag="LLC22_001567"
     CDS             10636..10974
                     /locus_tag="LLC22_001567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative DNA-binding protein"
                     /protein_id="HBK5434849.1"
                     /translation="MEIEKTNRMNALFEFYSTLLTEKQMNYMELYYADDFSLGEIAEE
                     YEVSRQAVYDNIKRTSKILEDYEKKLHLFSNYIVREQVLENMTAYITDKYPEDKKLLE
                     YVQQIQAIEE"
     gene            10995..12413
                     /gene="ffh"
                     /locus_tag="LLC22_001568"
     CDS             10995..12413
                     /gene="ffh"
                     /locus_tag="LLC22_001568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle protein"
                     /protein_id="HBK5434850.1"
                     /translation="MAFESLTERLQQAMGKIRKKGKVSEADVKEMMREIRLALLEADV
                     NLQVVKDFTKRVRERAVGAEVLESLSPAQQIVKIVDEELTITLGSETAELNKSPKIPT
                     VIMMAGLQGAGKTTFTGKLANYLKKNENARPLLIAGDVYRPAAIDQLKVLGQQLDVPV
                     FDMGTEVSPVEIVRQGMELAKEKKNDYVLIDTAGRLHIDETLMDELKQIKELTQPNEI
                     LLVVDAMTGQDAVNVADSFNQQLGITGVVITKLDGDTRGGAALSIRSVTGAPIKFIGS
                     GEKLTDLEVFHPDRMASRILGMGDMLTLIEKAQQDYDEKKAEELAQKMRENSFDFNDF
                     IEQLDQVMGMGPLEDLIKMIPGMNQVPGIENVKVDPKDVERKKAMVYSMTPAERANPD
                     LLNPSRRRRIAAGSGNSVVEVNRMIKQFKESRKMMQQMSKGDMNIPGMDQMFGSGVKG
                     KLGKMAMNRMIKKNKKKKKKRK"
     gene            12525..13103
                     /locus_tag="LLC22_001569"
     CDS             12525..13103
                     /locus_tag="LLC22_001569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306269.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-3-methyladenine glycosylase I"
                     /protein_id="HBK5434851.1"
                     /translation="MRCPWSEQTESMRQYHDTVWGVPEYDDQKLFRKLMLDINQAGLS
                     WQTILNKSEAFDEAYDRFDIKKVANYGETKISELMENKGIIRNRRKIEAAVQNAKAVL
                     KIQEEIGSFSEYLWSFSNGKIVDSSYHSQEEVPTTSPLSDELAKDLKKRGFKFIGSTT
                     IYAFLEAVGIINDHLDSCFRKEEVVRIGRKGE"
     gene            13107..13628
                     /locus_tag="LLC22_001570"
     CDS             13107..13628
                     /locus_tag="LLC22_001570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329440.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5434852.1"
                     /translation="MRKIIFYGAISLDGYLATKTDDLQWLFDTPTGKQTTYEAFYETI
                     DTTIMGRKTYQEAKKYLETEAIYPEKKNFVFSTHAQLQLPDAEVVNEDPVAFLKNLQM
                     TEGKDIWVVGGGRLIKPLLEHQMIDEWYIQITPVLLGDGIPLFQKGTYEARFEMLDTT
                     RFGEFIELHYVRK"
     gene            complement(13707..14261)
                     /locus_tag="LLC22_001571"
     CDS             complement(13707..14261)
                     /locus_tag="LLC22_001571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent oxidoreductase"
                     /protein_id="HBK5434853.1"
                     /translation="MTKKIGFFIGSLRKDSYNKKVAEAFAKLLPEGYESVFVKIDDLP
                     FYNEDLETPEQAPAEWTRFREEVRGLDGVVFVTPEYNRSVPAVLKNALDVGSRPYGHS
                     VWDHKPGLVVTASPGGIGGFGANHHLRQSLVFLNVPTLQQPEAYIGNVANLIDENGNI
                     VEGTLSFFQTILDAYLDFSNKLTE"
     gene            14514..14789
                     /gene="rpsP"
                     /locus_tag="LLC22_001572"
     CDS             14514..14789
                     /gene="rpsP"
                     /locus_tag="LLC22_001572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016175618.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S16"
                     /protein_id="HBK5434854.1"
                     /translation="MAVKIRLKRMGSKKSPFYRIVVADSRSPRDGRFIETVGTYNPLK
                     DPAEVVLKEDLVLDWLSKGAQPSDTVRNILSKEGVMQKHHEAKFSKK"
     gene            14801..15052
                     /locus_tag="LLC22_001573"
     CDS             14801..15052
                     /locus_tag="LLC22_001573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KH domain-containing protein"
                     /protein_id="HBK5434855.1"
                     /translation="MKDLSDLVLTIVRPLVTYPDQVKLDVVESKDFYEYNLTVAPEDI
                     GRIIGKQGRVAKAIRTIVYGVRINAPKKVRLNIIDDKEK"
     gene            15177..15968
                     /locus_tag="LLC22_001574"
     CDS             15177..15968
                     /locus_tag="LLC22_001574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434856.1"
                     /translation="MRKKMLFIPFALLLSACSSVTQESDNTHLSSSISETVTSPEKSS
                     TKTASTTEQTMATSNNEKKTALDQLKEQQPNVPMPLDVPVSSGYLNIAATHTKQGYSI
                     LYYRTDRPLGLNADELNQETPIATYLYQYGFASSQETIQVLQPFEIDTNGQQVDLGSR
                     ITGYQQGAAGSSFLEWQEGNWRIRIRGNNIEGQDPLLLAKEIVAYLEENSLPAPEQFG
                     KITVDMGDTTNRAVEVSWQEPKNAYTITHQDPMSALKMAVSMKRL"
     gene            16138..16659
                     /gene="rimM"
                     /locus_tag="LLC22_001575"
     CDS             16138..16659
                     /gene="rimM"
                     /locus_tag="LLC22_001575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimM"
                     /protein_id="HBK5434857.1"
                     /translation="MTEYLNVGKIVNTQGIKGEVRVISTTDFPEERYKKGTVLTLFQD
                     GKAPVELTVKSHRKHKNFDLLSFEGHPSINDVEKYRDGILKVSKDNSVDLAENEFYYH
                     EIIGLHVLEDGTELGKVKEILSPGANDVWVVQRPKKADILLPYIASVVKEVDLEAGVV
                     RVEIPEGLIDDED"
     gene            16649..17410
                     /gene="trmD"
                     /locus_tag="LLC22_001576"
     CDS             16649..17410
                     /gene="trmD"
                     /locus_tag="LLC22_001576"
                     /EC_number="2.1.1.228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (guanosine(37)-N1)-methyltransferase TrmD"
                     /protein_id="HBK5434858.1"
                     /translation="MKIDVLTLFPRMFGGPMGESIIGKAVDKGLLDINISNFRDYSDN
                     KHQTVDDYPYGGGAGMLLKVQPIYDNIQAIEKAAPDVKKRVILLDPAGKRFDQKMAEE
                     FSQEEHLVFICGHYEGYDERIRTLVTDEVSLGDYVLTGGELGAMVMIDATVRLLPDVL
                     GNQTSAQTDSYSTGLLEHPQYTRPAEYKGMKVPEVLTNGNHKLIEEWQLKESLRRTYQ
                     RRPDLLETLEWTPQMTKFLEEIKKEEQEKTADEAK"
     gene            17546..17893
                     /gene="rplS"
                     /locus_tag="LLC22_001577"
     CDS             17546..17893
                     /gene="rplS"
                     /locus_tag="LLC22_001577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357176.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L19"
                     /protein_id="HBK5434859.1"
                     /translation="MNPLIEELTKEQLRSDIPAFRPGDTVRVHAKVVEGTRERIQLFE
                     GVVIKRRGAGISETYTVRKVSNGVGVERTFPLHTPRVAKIEVVRYGKVRRAKLYYLRA
                     LHGKAARIKEIRR"
     gene            18266..18928
                     /locus_tag="LLC22_001578"
     CDS             18266..18928
                     /locus_tag="LLC22_001578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010740290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434860.1"
                     /translation="MKQNDGRIIWKNQSELKLILTINEFIEKHGITSSRQYQKKLSEN
                     PNSAPSMWFINKKYGSWENLLISIGRENTGYGKWARMSEQELLEIVEAFIKCEKITSQ
                     RMYEQKSVGKNIPSLSTIKKMLGDIRPLFKEKNDGSRFTDFELLLELKNEIIRLKLQD
                     DLSMTKFRKLVQSPKLPSVDTIMKRTNKNWEELMAEIGFDYRRIKIYKQRNNLSKTKK
                     TK"
     gene            19007..22234
                     /gene="fss3"
                     /locus_tag="LLC22_001579"
     CDS             19007..22234
                     /gene="fss3"
                     /locus_tag="LLC22_001579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286924.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBK5434861.1"
                     /translation="MKKPRFKNWRLLATLSLLCQTIGGSLGPTIAFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGVKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSEKAKLVSVLWKEAGTDVDTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     ESKINQAIADYQKKPSFHNSTVKTVLGQSTTVTDTNGLNLSEFDEVVENIANIDYRVN
                     GNQLVITPNANSKESGELTLKKSANTGTPVAYKMAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKETGNVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGAKVTIT
                     EKSVPAPYTIDTTPITATIKSGETISVTSKNTREKGQIILNKMGVETGTDLWNDKYSL
                     AGNTFAIRKDSPTGEIVQEMTTDEKGHAETPKEIANALELGTYYVTETKASNGFVNTF
                     KPVKVELNYVNQTVALVTSNVKGQNQEITGETTLTKEDKDTGNETQGKAEFKGAEYTL
                     FTAKDGQAVKWSEAFKPELVKGTKASDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYTLDETKYPVSIKKVDDNEKNAVITRDVTAKEQVIRFGFDFFKFAGSAAGTAETGF
                     NDLTFKVSPLEGTSEITGAEDEAITAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKADYTKSEYIFTITEKGQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLGTWKDGGKELTDLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     EATKAAQEKDEKAKPVVIAETTATLANKEKTGTWKILHKLTAEQVLDKTIVLFNYVYE
                     NKKPYEAGDDPVAKDASLNNQAQTVNCTVERHVSIQTKAHLEDGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDNTTKEIWKSGKIDYEVNDKEFTKTVLAEKVDT
                     SKYPEGTSFTFKEINYGKDGNINGKHNEDLKEKTQTLTPKKVPTTPSAPEQPEIPTVP
                     SDSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            22348..22662
                     /locus_tag="LLC22_001580"
     CDS             22348..22662
                     /locus_tag="LLC22_001580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5434862.1"
                     /translation="MELKFVVPDMAETFGKIRYAGEGEVLTEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            22675..23049
                     /locus_tag="LLC22_001581"
     CDS             22675..23049
                     /locus_tag="LLC22_001581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5434863.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTVSNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIMDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPDQGNSTNQNEGKK"
     gene            23059..23403
                     /locus_tag="LLC22_001582"
     CDS             23059..23403
                     /locus_tag="LLC22_001582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330683.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelB/DinJ family
                     antitoxin"
                     /protein_id="HBK5434864.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLTKALTYDEKMFLIMHQGLL
                     EVGNDAEEDFDVLNWLGEEESFFMVIEVNESLCREAETVLEEIGVEMPDAIEVFLKQL
                     VETKQLPIAVND"
     gene            23474..24619
                     /locus_tag="LLC22_001583"
     CDS             23474..24619
                     /locus_tag="LLC22_001583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002366015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBK5434865.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQELRQFDI
                     SKLSLSTIEIVRSIKDLIYLLGSLVLSGSTMLLYIHFFQDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTKETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDIIANRIGIDEVVAESGALRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFVLDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMTRSKAMKEMPNYKTGENYAFLGLPPNFLIFDEYVVYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRDQCATCF"
     gene            25334..27193
                     /gene="ltrA"
                     /locus_tag="LLC22_001584"
     CDS             25334..27193
                     /gene="ltrA"
                     /locus_tag="LLC22_001584"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBK5434866.1"
                     /translation="MNKVKTNKTLRHSEYYGMTQIFDELYVKSDKKEVFTELMTIIMS
                     DENIRLAYRNIKNNKGSYTASTDKKSIRDIKTLSEDTFLTEVKVLFRCYKPRAVRRVE
                     IPKPNGKTRPLGIPSIWDRLIQQCILQVLEPICEAKFHNYSYGFRPNRSTHHAIATCN
                     RLANRGKLHFVVDVDIKGFFDNVNHSKLLRQMWTIGIRDKWLLGIIRSMLNAPIVLPT
                     GKVEHPKKGVPQGGVLSPLLSNIILNELDWWVASQWQNTTIETEKIMDRRDKGKGIDK
                     TNQYRALRRTNLKEIYIVRYADDFKIFCRKRSHADKIFHATKMWLKERLSLEISEEKS
                     KIVNLKKGKSEYLGFELKLIKKGKKYVVESHMSKKSMTRVKIQLKKQLRKVARPKNHC
                     EQAKEIGLYNSMVIGIHQYYGIATCVNLDCSKIAYTLKPFINHKLPTKKHGKILNTFI
                     KSKYGKSKEMRWLNNVPIVPLNYVQFRLAVPLSEGTCKYTESGRSKIHSKLKLDLALL
                     LHMMRNSNYERSIEFVDNRISKYSAQKGKCAITGKFLEYEEIHCHHIVPVKQQGTDKY
                     SNLIIIHKNVHALVHAIEEKIIHKYLNVLNLTNEQIEKLNELRVKAGNSVLTV"
BASE COUNT         9288 a         4756 c         5581 g         7686 t
ORIGIN      
        1 ttattgcttt tgcaaaattt atttacctgt tttctggatc aacgatagtg tacattatgc
       61 tatccttgtt tggattttag gacgtttaaa gaggcacttt tttacataac ttaatccata
      121 gaccttttaa gcatgctgtg agataataat aaagaagagt ttaaagcgca ccccaaacca
      181 cttccccata agtgtattac gctttaaact cttttatatt tgaattcact aagaagcata
      241 ccatatattt gaatttacta agaagcatac catatttttg aaaaaaagtg agaaaaaagg
      301 cttataatta ggatttagag taattaatta gatgtttatt ttataggact gatactatag
      361 attacaaata gtatcgtatt tcgcaatctt aaaattatct tcttactgtg aataagataa
      421 taaaatttgt atttgtcctt tttaggtaac ttattttaat ctatatacct ttctggatca
      481 acgaaagtat actttatata gtcataacgc cgatggtaac tatgcactgt aacgataatg
      541 ctgctaaaat atctttttac gaaaaacatc acaaggaaaa acttaactat ggtattatct
      601 aaacataatt ttttcggtat ttaatattta attaggaggt aatattttgc ttttttatag
      661 taattttatc ttaatagtag cgatattatt acttctgaat atatggattt ttgataggag
      721 tagaaattca agtataggtt ttagaactaa acgaagtttg tcttctaaaa aaaattgggt
      781 atactcacaa actatttttt atggaggaat tgttttaatt agtttacttt cttcaacact
      841 ttattctttg aatattatag atgtttccac ctcaaattca atatctatta ttggaatcat
      901 tattgctgca attattacac aactgttttt agtgtttgga gagaagaaaa gaagtaaaaa
      961 atagaaaaac tagtgatagt tttggtgata taagaaaaac atatatgtat aaaaagaaga
     1021 aagtagcttc tctttgtaca tatatggttt gtttttatgg atgccgagct tttttataag
     1081 ataaggctac cgcccataac gacccaagga tttgtggaac taagtaaata cctgcaagaa
     1141 gcaagatcag ctgggtcggt tttaaaggat gatagaagta acgccattca gtaaaattgg
     1201 cgcaaaataa ataggaagtg acagtagata taatattggc aatgaataaa gatataatac
     1261 gcctgttcct ttgaaaataa tatccagcaa aaagagataa aaatatcaat gtgatgaacc
     1321 cgcttacgga atgataacga aaatcaagca gtaaggcgaa atgcacataa ggaacaaaag
     1381 ataaaagcaa cggaaggttt ttccagcaag tttttatcat ctttcatcac cacctaacaa
     1441 gtgttattat tttgttagtt ttattgtaaa ttgaatcctg caataatcaa ttactttttc
     1501 attatttcta gattaaatga ataaactctc atgccattat ctctaaaaaa aaagtttttc
     1561 cccctaattt ttttagatag aaaattgtat agtatgatga gagaaaaagt agtttggggg
     1621 aacgttaatg agaagaaaag cagtaatcga tcggctttat ttattttttt ggttttttcc
     1681 tatcgttttg ctacctttta catgggtaaa tgctgttgta caaggtgcgg agatattagg
     1741 cctgatccaa ggaagcggat ttgtggtttc taggaatttt ccagctttga ttgttttcta
     1801 tttagtgata agtgtaggtc tcttattacc aaaatctctg atcaatcact acaattggca
     1861 gctgctttac ttttcttgct tattagtatt tacatctatg ttttctttgc tgcctcgctt
     1921 gattatcggc cctaatggtt tgagcgagag tggattgaag gatttagctt attcctccat
     1981 gtatttcttg acgatcaaac catggttcta tttagtaatt gcctcattta ttcttgcaac
     2041 atttttttac ttctggacag aaatcaggat aaaaagtgaa cgatctgtat ctataaaaaa
     2101 taactattga tggtggatca tcagtaaaaa aacatatgag ctgcgtaaaa tgcatgtttc
     2161 tcatatgctt tttttattat tatgtaaaga atgcgaaaaa cgtttacatg atttttacat
     2221 aacttaacta tatttttaca gcaaccatac gagggattta cagtcgactg ataaacttta
     2281 gttgtaaata agaaaggagc aataaaatga aaaaagtatt gtttactcta ggtatgatgg
     2341 gaattctttt agccggatgc ggctcaggat caggaaatac agatggctct gccacacaaa
     2401 ataattcaag tgactcaaat gaacaagtaa aaatcgttgc ggtaggttcg acagcattac
     2461 agccgttagt cgatgcagca caagaaagct ttgtacaaga aaatccaaat tatcaaatct
     2521 ctgtacaagg aggaggaagc ggaactggtt tgagccaagt cgaagctgga gcagttacta
     2581 tcggaaactc tgatgtattt gcagaagaaa gagacggagt tgatgcttca aaattagtgg
     2641 atcataaagt agcagtggtc gggatggcac caatcgtcaa taaagataca gatgtcaaag
     2701 atatcaccaa acaggaattg attgatatct ttacaggaaa aatcactaac tggaaggaag
     2761 ttggcgggaa agatcaaaaa atcaacgtcg tgaaccgtgc aaacggcagc ggtacccgcg
     2821 cgacattcga aaaatgggga ctggatggtg ctacccctgt gcagtcccaa gaacaagatt
     2881 catcaggaac agttcggcag ctggtaagtc aaacaccagg agcaatcagc tatttagctt
     2941 tctcatatct cgatgattcc acacaagcac taagtatcga cggtgtagaa ccaaaagaag
     3001 agaatgtagc agataacagc tggggaatct ggtcatatga acatatgtac acgaacggaa
     3061 aaccttcccc tgaagtccaa aaattcttag actacatgat gacagaagaa atccaagaag
     3121 gacctgtcaa agaattgggc tatttaccaa tcacaatgat ggaagtagaa cgtgatcacg
     3181 aaggaaatat caaataacta gcagataaac atgccacggt agtcgttact attaaggaaa
     3241 aatcaactat gtttccccac atatacattt ttcctttaat tgtgaaaaat agttcctcat
     3301 attttgccgt tttttgagct aataccgagg gtcagctgat tgaacaccgt ttattcgaaa
     3361 aaaagagcta cgacatagaa ctgtcgtaac tttttttggc tcttcgtcaa atcgtgttgg
     3421 tgaagacaaa tttgaataaa acttagtccg atatgcggcg cgttctgtgc gccgcatatt
     3481 tttttagttt tcaaagatca gaccttgttg taaatagatc cgtgcccgaa agttataaaa
     3541 gttgcgataa ccaaacgcaa ttcgtttaat cagcttgatc ttgttattca gcccctcagt
     3601 gacgccgttt gagtgggaca ccttaaaggc atttgaaata cccgattggt agcaatggaa
     3661 gatcgtgaat ttctttttaa acgactgagg taacgtagat gaaattgttt taagggtttc
     3721 ttgaaagcct tccgtacctc gtttaacgaa ataatagcgt aataattgac aaaaatgata
     3781 cgcagttcgc aattcttcgt tgtagcttaa cagctcatca acgatttctg tttgactaat
     3841 tggtcgttta aacagtcgat gataatgccg tttgagtggc tcccatgtcg tggaatcttt
     3901 gagtaagagt ttccaatatc gcttgagccg acggtacttc ttctgatttt cagagtgtga
     3961 ggttcgaaaa cgattcatga tctggacacg taattgattg aagctgcgat tgatgtgttg
     4021 gacaatatga aagcggtcag ttacgatctc cgcatttgga aagactgttt taagcaactg
     4081 acaatagctg gcattcatgt ccatcactag gtacttgacc tttaaacggg cctttctagg
     4141 aaagcgcagg aagtattgag ttagtttgta aagtctgcga tcttcaagga tcgtaaatag
     4201 ctgattggtt gtcccatcaa cacaaataaa actcatggaa ccagaaacag aattcattga
     4261 tttgaactca tccatacaca acaccgtcgg aaggaagttc atacgtggct ggtaatgctt
     4321 cgttgcttca cgcaagatcc gtgtcaccgt cccatccgag acgaagtact tcttagcgat
     4381 tagtttacgt gattgatttt cgtacagttc catgagaatc gcctgcttca gttcctttgt
     4441 tagttgatga tgttcatcaa ctaagtccgt tttcgcagaa aaggtccttc cacaatcatg
     4501 gcagagaaaa cgggtacgtt ttaattctaa aatagttaac ttttctttga ctttcaacat
     4561 ctgagtgcgt gtcgtatagg aaccgttgcg gataatacga accgatcgac agtgttcaca
     4621 ataggaagaa gagtcatcca attttccttt aataaactgc gcttgaacgc ctttatattc
     4681 tttttcaatc agccattctt catcaaaaaa taaatgttta tctgttaatc cgagtaattt
     4741 tctagtatga ttatccattg agagactcct ttggtaggat gacgttttgg tcgactaaat
     4801 tttaccaaaa gtgagtctct ttttgagttg aaacgaagaa aaagtgttag tagaaaatcg
     4861 ccttcgattt tccaccaaca caaaatatta tagaaccctt tttttttgct atatgacagg
     4921 aatgaaaggt gtttgcaagc ttaatgtgag gaacactttc catatctgtt ctatactgga
     4981 taggagaagt ttggaaatat ccagaaaacg aaatcaatcg aggtagccac atgaagaata
     5041 aatggataaa tcgaagtaaa aaaaagaaag taacacaaag atcatcagat aaagtcatcc
     5101 gtctttttcc atcgtataaa gaaggattaa cggcagatca agtcaaggaa cgaatagaaa
     5161 aaggtgcagc aaataattca gtcgatccca cattcaaaac aaatcagcaa atcgtattgg
     5221 aaaacatatt tacgtatttc aatttgatct ttcttatctt agccattttg ctttgtttag
     5281 tagaatccta taagaacttg acttttttac cagttatcat agccaataca ggaatcgcca
     5341 tttttcagga aattcgatcc aaaaagatct tggacgaact aaatgtttta aatacagcaa
     5401 aagtcaatgt catacgagac gggatagaac aaacaataga tatagaagac cttgtaatag
     5461 atgacattgt tattttagag actggatatc aaattccagc agatgcagag gtcgtggaag
     5521 ggaaactgca agttaatgag gctttattga caggcgaagc agatgaaata accaaagaaa
     5581 taggtgatcc attaatgtcc ggcagtttca ttgtttccgg aaaagcttac gcccgattag
     5641 acaaagttgg agcagattcg tatatttccc agctgacagt caaagccaag acaatgggag
     5701 aaggagaaca gtcggagatg attgcttctc ttaatcaatt gatcaaatgg attgggatca
     5761 tcattattcc tatcggtatc ctgctttttt ctcaaagtta cttttttaat ggaaacacga
     5821 tcaaagaaag tgtcgttgca atggaagcag cattgatcgg tatgatacct gaaggactgt
     5881 acttgctgac gacgattgca ttagcattaa gtgcgactaa actagcaaag caaagagttc
     5941 ttttacacaa tatgaaaagc attgagacat tggcaagggt aaatgtcctt tgtgtagata
     6001 aaacaggaac gatcacagaa aataaaatgt ctgttcaaaa aatgatcgtc tctaaaaaac
     6061 aagaaataat cagtcagtca gatcaattgg aagcatgcat tgctgactat gcaaaagcga
     6121 tggcaggaga caatgcaaca atggaagctg ttaaagcata ttttacaaaa accactgatc
     6181 aatcctatca ccatgttatt cctttttctt ctgtccaaaa attcagcagt gtagcgttgg
     6241 cagacaaggt gtatgtttta ggagcgcccg aaatggtttt gcgcgatcaa ttgccggaat
     6301 atgcggaaga gtttgtttct ttcgctgaaa aaggctatcg cgtgttggtc tttggtgtgt
     6361 acgatgggat tcttgaagaa ccagtattga cagaagcagt cacaccatta ggctatattc
     6421 tgattgctaa tcctatcaga aaagaagcaa gagccacatt tgattacttc aaaaaacagc
     6481 aagtagccat caaagtgatt tctggagata atccgctcac cgtatccaat gtagctgtcc
     6541 aagcagggat ttcacatgct gatcagtacg ttgatgcatc taaattatca gaagaagaat
     6601 atgaagcagc tgtcgaaaaa tatacagttt ttggacgcgt caagccagaa caaaagaaaa
     6661 tcttcgttca attgataaag cgtaacaata cagtagctat gacaggtgat ggcgtgaatg
     6721 atattctagc catgaaagaa gcagactgca gtatagcgat ggcttccgga aatgaagccg
     6781 ccatgcaggc ctcacaagtg gtcttacttg attctgactt ttcacgcatg ccagaagttg
     6841 ttgcagaagg acggcgcgtt gtgaacaata ttgagcgatc agccagcttg tttttagtga
     6901 agaatatttt ctcctttttg ctctcactgt tttcagtgat ctttgctctg acctatcctt
     6961 tagaaccatc acaaatcaca ttgattagtt tgtttactat cggacttcca tctttcttgc
     7021 ttgctctaga agaaaacaaa aagcgaatca gagggaaatt catcatgaat gtgatggaaa
     7081 aagctgtgcc aggtggacta acagatatga tcgtagtcgg tgcgttggtg atctgcgggg
     7141 tgactttgaa tctaaataaa acagatgttt ctacagcatc taccatgctt ttgattgcag
     7201 tagggttcct cgttctctat aaaatctgtt caccgctgaa taaattcaga agtcagatca
     7261 ttcttttctg tgctagcggt aacttttttt cggtcatctt tttgcataag ctgttttcaa
     7321 tcaccggtat ctcagctgta tcacttttgc tgttgagcat tctatttttc tcggcagatt
     7381 cgatttttag gcatttgacc acattggtag aatatttgtt tgaacgtaaa aatgaaaaag
     7441 agcaaaagcc gtttagtcgc gtagctaaaa aatttctatc gatatttaaa cgagaaaatt
     7501 gacgaaaagt atctcaaaaa agagtaaaaa agaacaacca ctcgtgtatc tttcgaagca
     7561 ggatgagtca tccaacttta aaacgcacga gcagttgctc ttttttacat tttcggaatg
     7621 gtaacggtga aagtcgaacc tgttccaaga tgactgtcta cagtaatcgt accattaagg
     7681 agttgcacgt agtcttttac aatcgctaac cctaatccgg tcccgcctga atgtcggctt
     7741 cgcgccttgt ctacgcggta aaaacgctca aagatccgtt cctgatcctc aatgtcgata
     7801 cctataccaa agtcttggac agaaaacgat agatcatctg ttgcctgata gcggataata
     7861 atctcgctgt cgctttttga atattggaca gcattttcaa tcagattttt gataattgga
     7921 taaaggatat ctgttttagt agtaaatggt tcgttctttc caatcaatcg aatcgtcaac
     7981 cgtttctttt cgatgattgg ctgataattt tgaacgattt gctggaaata aggttctgta
     8041 taaattgtct ggatctcgta agaattctcg ccatcttttg acagctggat gatttcccga
     8101 atcagtttat ctaaccggat cgcatctttt tgcatgatct caagaaaaga agtcagagtt
     8161 tgcgggtcat cttttgcacc atccagtaaa gtctcggtaa aaccaatcag tgaagtcaca
     8221 ggagttttta attcgtgaga gacgttgcca acgaaatcct tttgtagctt ttctaaacgt
     8281 cgcactttcg ttaagtcata cgccacccct agaatctgtc cggtaccttc tgaattagta
     8341 aagtagcgca aactcaagtc taatgtctgc cgaccttctg taagggtgat ctcctgatgg
     8401 atcagcggat gctcaggagt cacttgatga atcagctgaa tgagttttgg ctcttgaatg
     8461 acttctgtgt accgctgttc aggttgatag cttaccacgt ttaaatgtag ctgcatcttt
     8521 ggattaagca gtagtaaacg agaatcagca tcatcaatca ggaatacgcc aatcatcagt
     8581 tcgttcagta acgtatataa ttgctcttct gtggtagtac acgcccgata catcttactc
     8641 atttgttcgc tcaacgcatt aatcgtctga tacaattctt cccattgatc gggtgtttgc
     8701 atgattactt ccgcctgatt aggattttgc accatttttt ttagtacggg cagcacggtt
     8761 ttcaatggct ggtttttttg atagatcaga taatagatca ttcctgcaag aacaaggaag
     8821 aaagacagaa agaagaaaaa gacccaacgg cgaaaactct cagttctcgg taaaaaaacg
     8881 cttgtcggtt ctgcgatacg taaaatggct tctaactggc cacttttttt gactggtaat
     8941 gcgacatata aaagatcctc attcaaagta gtacttttgc gcaaagcgct acctaggttc
     9001 ccaccattca atacggcttt gatttcggga cgggagtttc gctgttcatt caatgtttca
     9061 ttgtttgtgt caaataagat ctttccagta gcatccatta aagtaatccg ttcgttcgac
     9121 tgatggacga attcttccaa agcagttttg ttttgcgctg cttggaggtt ttcgacatct
     9181 aattgccgga tcagcagttg tgcttttttt gtcaggtagc tttcttgctg ttccacgatc
     9241 tgctgttgaa aataatggga aatcaattgc cagccaccaa aaaacaaact aactaaaaga
     9301 ataagaaaga agagacgttc ataaattttt ttccatttca tcgtttgggt tcctgaaact
     9361 tatagccaaa tcctctaata gtcaccaagt actttgggtg ttttggatct cgctcgattt
     9421 tttctcgcaa atgactaacg tgtacatcta cgattcggct ttgtcctgcg aagtcaaaat
     9481 tccaaatgcg gtctagcaat gtgtctcggt cgatcacacg gtcttttcgt ttcatgaaat
     9541 aaacaagtaa ttcaaattct ttcggtgtta gttcaatcag atggtcgtct acggtcactt
     9601 gataattggt caaatcagca gtgatttgtc caatcgatag atattcaggc tcagcttcat
     9661 cttttgattg cttacgaggt tcaattcgtc tgaatattgc tttcatacgg gctaatactt
     9721 cgcgaggact aaatggtttg gtcaaatagt cgtcagcacc tatttctagg ccaatgatcc
     9781 gatccacttg gtcatcttta gccgtcagca tcaaaatcgg tgtttcattt ttttcttgac
     9841 gcagccgctg agtgatctcc atgccatcca tcgttggaag catcacatct aaaatgatga
     9901 aatcaaatga ttgttctaat gctaattcta atccttcgcc tccatctgtg gcactggtta
     9961 ccttgtagcc ttctttttcc aaattgaacg tcaagagcgt tacaatagaa ggttcatcat
    10021 caacaactag tatttttttc attcaaatct cctttaaata ggtttcattc tgtttatatt
    10081 ttagcataga atcagtacaa agggctattt tacaaaagaa ataaatggta taataggaag
    10141 gcactttgct gaatagaaag gaagagcagt caatgattgg aatcagtgca tgtttaggcg
    10201 gtctggcctg tcgctatgat ggacagaaaa aagaagtacc agaattgatg gaactagttg
    10261 aaactggaga agctgtcatg gtctgtccag aagtgatcgg cggattacca attcctagag
    10321 atcccgctga aatcattggt ggaaatggat tcgatgtgtg gaaagatcaa gcaaaagtat
    10381 ggacgacaag cggcgaagat gtaacggaag cgtacaaaaa tggcgcgatc aaagcctatc
    10441 aaaaattgca ggaaaaacac attgatctag tcatcatgaa ggaaaaaagc ccttcatgcg
    10501 gaacccattc gatttatgac ggaagttttt ccggaataaa aaaaaatggt gccggagtgg
    10561 ctactgctta ttttattcag caaaaaatga ctgtgctctc tgatgaagaa tggctgaaaa
    10621 ctagaggtga gcagaatgga aatcgaaaag accaatcgaa tgaacgcgct ctttgaattt
    10681 tattcgacct tattgacaga aaaacaaatg aactacatgg aattatatta tgcagatgat
    10741 ttttcattag gtgagatcgc ggaagaatac gaagtaagcc gacaagcagt atatgacaat
    10801 atcaagcgga caagcaagat cttggaggat tatgaaaaaa aactccatct tttttctaat
    10861 tatattgttc gagaacaggt attggaaaat atgactgcat atattacaga taagtacccg
    10921 gaagataaaa aactacttga atatgtacag caaattcaag caatcgaaga ataaataaaa
    10981 ggaatgaaga aaatatggca tttgaaagct taactgaacg tctccagcag gcgatgggaa
    11041 aaataagaaa aaaaggaaaa gtatcagaag ctgacgtaaa agaaatgatg cgggaaatcc
    11101 gccttgcctt actagaagcc gatgttaact tgcaagtagt caaagatttt actaagcgcg
    11161 tacgcgaacg tgcggtaggg gcagaagtgc tggaaagttt atcacctgca caacaaatcg
    11221 taaaaatcgt tgatgaagaa ttgacgatca cacttggttc tgaaacagca gagttaaata
    11281 aatcaccaaa aataccaact gttatcatga tggctggtct tcaaggggca ggtaaaacga
    11341 cctttactgg taaattagcc aattatttaa agaaaaatga aaatgctcgt ccgctcctaa
    11401 tcgcagggga cgtatatcga ccagctgcga tcgaccaatt gaaagtatta ggtcaacagc
    11461 tagacgttcc tgtatttgat atgggaactg aagtcagccc ggtagagatc gtccgtcaag
    11521 ggatggagtt agcaaaagaa aagaaaaacg actatgtatt gatcgatacg gcaggacgtc
    11581 tgcatatcga tgaaacattg atggatgagt tgaaacaaat caaagaattg acgcaaccaa
    11641 atgagatttt gcttgttgtc gatgccatga ctggtcaaga tgccgtcaac gtagctgata
    11701 gcttcaacca gcaattaggt attacagggg tcgtcatcac taaacttgat ggggatactc
    11761 gaggcggggc agcactatcg atccgctcag tgacaggcgc accaatcaaa ttcatcggtt
    11821 ctggtgaaaa attgactgac ttagaagtat tccacccaga tcgtatggct agccgtatcc
    11881 ttggtatggg ggatatgctg acattgattg aaaaagcgca gcaagactac gacgagaaaa
    11941 aagcggaaga acttgcacag aaaatgcggg aaaattcatt cgatttcaat gactttattg
    12001 aacagcttga tcaagtgatg ggtatgggcc cactggaaga tctaatcaaa atgatcccag
    12061 gaatgaatca agtccctgga atcgaaaacg tcaaggtaga tccaaaagat gttgaacgca
    12121 aaaaagcgat ggtttattct atgacgccag cagaaagagc aaatcctgat ctgttgaacc
    12181 caagccgtcg tcgccgaatt gctgccggtt ctggaaacag tgttgttgaa gtgaatcgaa
    12241 tgatcaaaca attcaaggaa tcaagaaaaa tgatgcagca aatgtccaaa ggggatatga
    12301 acatcccagg tatggaccaa atgtttggtt caggcgtcaa aggaaaacta ggcaaaatgg
    12361 cgatgaatcg aatgatcaag aaaaataaga agaaaaagaa aaaacggaaa taagatgaaa
    12421 aaaacagctt cggtacagac tgaaaatgtc tactgccgga gcttttctat cagcaatttt
    12481 tattctttac taatacaatt actctaaacg aagaggtggc acagatgaga tgtccgtgga
    12541 gtgaacaaac agaaagtatg cggcaatatc atgatactgt ctggggtgtt cctgaatatg
    12601 atgaccaaaa gctgttccga aaattgatgc ttgatattaa tcaagccgga ttgagctggc
    12661 agacgatttt aaataaaagt gaagcattcg atgaagcata tgatcgattc gatatcaaaa
    12721 aagtcgcaaa ttatggagaa acaaaaatca gtgaactaat ggaaaacaaa ggaattattc
    12781 gtaaccgaag aaaaatcgaa gcagccgtcc aaaacgccaa agcagtcttg aaaattcaag
    12841 aagaaatcgg cagtttttca gagtatcttt ggtcgttttc taatggaaaa atcgttgatt
    12901 cttcttatca ttcacaagaa gaagtcccaa caacaagtcc tctttcagat gaattagcaa
    12961 aagatctaaa gaaaagagga tttaaattta tcggaagcac aacaatctat gcttttttag
    13021 aagctgtcgg gatcatcaat gatcaccttg acagttgttt ccgcaaagaa gaggtcgtac
    13081 gtatcggcag aaagggcgaa taaagcatgc gaaaaatcat attttatggt gctataagtt
    13141 tagatggcta tttggcaacg aaaacggatg atcttcaatg gctttttgac actccaacag
    13201 gtaagcaaac tacttatgaa gctttttatg aaacaatcga tacgaccatc atgggcagaa
    13261 aaacttatca ggaagcaaaa aaatatttgg agaccgaagc aatttatcca gagaaaaaga
    13321 atttcgtttt ttccacccac gcacaattac aattgccaga tgctgaggtc gtaaacgaag
    13381 atcctgttgc ttttctaaaa aatctacaaa tgacagaagg aaaagatatc tgggttgtgg
    13441 gtggcggtcg attgatcaaa ccgctattgg aacatcaaat gattgatgaa tggtatatcc
    13501 agattacccc tgtattatta ggggacggga ttcctttatt ccaaaaagga acatatgaag
    13561 cgcgttttga aatgctagac acgacacgat tcggtgaatt tatcgaattg cattatgtac
    13621 gaaagtagaa gtaaataaaa taaaaaaggc aactatatgc agaaatgtcc tgtacatagt
    13681 tgcctttttt attaccgtta tgctttttac tctgttaatt tgttagaaaa atctagatac
    13741 gcatctaaaa tcgtttggaa gaaacttaat gttccttcaa cgatattacc attttcatca
    13801 attagattcg caacgtttcc gatatatgct tccggttgct gcaaggttgg cacattcaaa
    13861 aagacaagtg attggcgtag atggtggttt gcgccaaagc cgccgatccc acctggtgat
    13921 gcagtaacga ctaaacctgg tttatgatcc caaacactgt gtccataagg tcttgagcct
    13981 acatctaaag catttttcaa tactgctggc acagaacggt tgtattcagg agtaacgaaa
    14041 acgacaccgt ctagtcccct cacttcctca cgaaaacgag tccattcagc aggagcctgt
    14101 tctggagttt cgagatcctc attgtaaaat ggcagatcat cgatttttac aaatacactt
    14161 tcgtaccctt caggaagcaa tttcgcaaaa gcttctgcta cttttttgtt gtaagaatct
    14221 tttcttaaac taccaataaa aaatccaatt ttttttgtca tacgattttt cctccttcaa
    14281 actatctata ataatcttac aaaagataag taactggagc aaataaaaac acttactgac
    14341 aaaagctaca tagaagatag attacttatt tttaacaaaa aagaagtcta aaatcttcta
    14401 ttttctaaaa aaaatcgaat ttaatcaagc tgtaaagaaa aaaagcttta cagggtaaaa
    14461 aaaaactgtt acactacatc ttgtgaataa aacaatggag gtggaaataa ataatggcag
    14521 ttaaaatccg tttaaaacgt atgggttcta aaaagagtcc gttttaccgt atcgtcgtag
    14581 ctgattcacg ttctcctcgt gatggacgtt tcatcgaaac tgtaggtact tacaatcctt
    14641 tgaaagaccc tgcagaagta gttttaaaag aagacttagt tcttgactgg ttatcaaaag
    14701 gtgcacaacc ttctgacact gtacgtaaca tcctttcaaa agaaggcgtt atgcaaaaac
    14761 accacgaagc taaattctca aagaaataag gtgaccggat atgaaagatt taagcgactt
    14821 agtcttaaca atcgttcgtc cgctagtcac ttatcctgat caagtcaagt tagacgtcgt
    14881 agagtcgaaa gacttttacg agtacaatct aacagtggct cctgaagata ttggccgtat
    14941 cattggaaaa caagggcgtg ttgctaaagc aatccgcaca atcgtttacg gtgttcggat
    15001 caatgcaccg aaaaaagtgc gtttgaatat catcgatgat aaggaaaagt aaataaacgt
    15061 gctgtactcg aattttcgag tgcagctttt ttgttttttt tattaattga agaaatgatt
    15121 atttggcaaa acaagcaaga aagcgtatcc ttataggagg agggagtgaa cagccaatga
    15181 gaaagaaaat gttatttatt ccatttgctc tattgttaag cgcttgtagt tcggttactc
    15241 aagaatcaga caatacacat ctatcaagca gtatatctga aactgttacc agtccagaaa
    15301 aaagtagtac caaaacggct tccaccactg aacaaacaat ggctacctca aataatgaga
    15361 aaaagactgc tttagaccag ttgaaagaac aacagccaaa tgttcccatg cctctagatg
    15421 taccagtctc ttcaggctat ctcaatatcg cagcgacaca tacaaagcaa ggttattcta
    15481 ttttatatta cagaacagat cgtcccctcg ggttgaatgc tgacgaattg aatcaagaaa
    15541 cgcctattgc aacctatcta tatcaatatg ggtttgcttc tagtcaagaa acaatccaag
    15601 ttttgcagcc atttgagatc gacacaaatg gtcagcaagt ggacttaggt tctcgaatca
    15661 cagggtatca gcaaggtgca gcaggttcaa gttttcttga atggcaagaa ggaaactggc
    15721 gtattcgaat ccgtgggaat aatatagaag gccaagatcc cttactatta gctaaagaaa
    15781 tcgtagctta tttggaagaa aacagtctac cagcacctga acaatttggt aaaattactg
    15841 ttgatatggg tgatacgacg aatcgagccg tagaagtaag ctggcaagaa ccgaaaaatg
    15901 cctatacgat cactcatcaa gatcctatgt ctgcgttgaa gatggcagtt tctatgaaga
    15961 ggttgtgaaa tcagcgcgct gatctgagcc catcatttaa ctccaagtca caggaagtaa
    16021 tcaaaaatag cacgccgcat ttttgcataa ttttggctta ataccttaaa agaaaactag
    16081 aattgcctct tcacacatgc taaaataaaa cagacaaaaa agaaatgggg atataagttg
    16141 actgaatact tgaatgtagg aaaaatcgta aacacacaag gtatcaaagg cgaagtccgt
    16201 gttatctcaa caacggattt cccagaagaa cgttacaaaa aaggaacggt gctaacacta
    16261 ttccaagacg gaaaagcacc tgtggaatta acagtcaaaa gtcatcgcaa acataaaaat
    16321 tttgacttat tgagttttga aggacatcct tctatcaatg atgtggaaaa atatcgggat
    16381 ggcatattaa aagtgtcaaa agacaactct gtagatctag ctgaaaatga attctattac
    16441 catgagatca tcggtctgca tgtattagaa gatggaactg agttaggtaa agtaaaagaa
    16501 atcttgtcac caggtgccaa tgatgtttgg gtcgttcaac gtccgaaaaa agctgatata
    16561 ttgcttccat atatcgcttc tgtcgtcaaa gaagtcgatt tagaagctgg agtggtccgt
    16621 gtagaaattc cagaaggact gattgacgat gaagattgat gtattgactt tatttccaag
    16681 aatgtttgga ggtcctatgg gggaatccat catcggtaag gctgtagata aaggattatt
    16741 agatatcaat atctctaact tccgcgatta ttcagataac aaacatcaga cagtagatga
    16801 ttatccatac ggcggtggag caggtatgct gctcaaagtc cagcccatct atgataacat
    16861 ccaagccatt gaaaaagctg caccggatgt caaaaaaaga gtaattcttc ttgacccagc
    16921 tggtaaacga ttcgatcaga aaatggcaga agaattttca caagaagaac acttagtatt
    16981 catttgtggt cattatgagg gatatgatga acgtatccgc acattagtga cagatgaagt
    17041 ttccttagga gattatgtcc ttactggggg agaattaggt gcgatggtca tgatcgatgc
    17101 aacagttcgg cttttgccag atgtgttagg gaatcagact tcagctcaaa cggattctta
    17161 ttcaaccggt ttattggaac atccccaata tactcgcccg gcagaatata aagggatgaa
    17221 agtaccagaa gtattgacaa atggaaatca taaattgatt gaagaatggc aattaaaaga
    17281 atcactaaga aggacctatc aacgtcggcc tgatcttttg gaaacacttg aatggacacc
    17341 tcaaatgacg aaatttttag aagaaatcaa gaaagaagaa caagaaaaaa cagcagatga
    17401 agccaagtga ctttttctaa aatcttcttt acagtaggtt gataatatgt tagtatttta
    17461 tggtgagtgc aaaagcactt aactattacg atattccgct gtgagaaaag ctcataagaa
    17521 tatttggaat aaggagaaga aaaccatgaa tccattaatc gaagaattaa caaaagaaca
    17581 attacgttct gacatcccag cgttccgccc tggtgacact gtgcgtgttc acgcaaaagt
    17641 tgttgaaggt actcgtgaac gtatccagtt atttgaaggt gttgttatca aacgccgcgg
    17701 tgctggaatc agcgaaactt atacagtacg taaagtttct aacggagtgg gcgttgaacg
    17761 tacattccca ttgcatacac cacgtgttgc aaaaatcgaa gtagttcgct acggtaaagt
    17821 acgtcgtgca aaattgtact acctacgtgc attacacgga aaagctgctc gtatcaaaga
    17881 aatcagaaga taaacacgga aaacttcctt ggaaatctga aatttgtgaa aagtccttgt
    17941 atatcaaggg ctttttcttt tttctctatc acagttttaa gccatttttg gctgttttgg
    18001 accatttttc aatcatattc ccttaaaaat tgtcctagat tgtccgacat tgactatcag
    18061 tgtcgtcaaa atagggcaaa atttagtagt cagcttgacg acaaatataa tacgaaaaat
    18121 accaaaacat ttaccgaatt tagcaacttt tgaacccaag tttctcaaag ggtcagctat
    18181 tagcaaaaaa gacaaaacat gtacttttct actaaaaagt tgatgtgata ggcttctatc
    18241 taaataacta ttaggagttt ttatcgtgaa gcaaaatgat ggacgtatca tttggaaaaa
    18301 tcaaagtgag ttaaaactga ttttaacaat taatgaattc atcgaaaaac acggaattac
    18361 atctagccgt caataccaga aaaagctatc agaaaatcca aattctgcac caagtatgtg
    18421 gttcattaac aaaaaatatg gatcatggga gaatttattg attagtatag gacgagaaaa
    18481 tactgggtat ggaaaatggg ctagaatgtc agaacaagaa ttattggaaa tagtagaagc
    18541 ctttattaag tgcgagaaga taacctctca acgaatgtac gaacaaaaat cagtagggaa
    18601 gaatattcct tcacttagta ccattaaaaa gatgttagga gatatacgtc cactttttaa
    18661 agaaaaaaat gatggatctc gatttactga tttcgaactg ctgttagaac taaaaaatga
    18721 aataatccga ttaaaactac aggatgattt atcaatgaca aagtttcgaa aactagttca
    18781 atccccaaaa ctaccatcag ttgatacaat tatgaaaaga acgaacaaaa attgggagga
    18841 attgatggca gagattggat ttgattatcg aagaatcaaa atttataagc agagaaacaa
    18901 cctatccaag acaaagaaaa ctaaatagta tcactctaaa tcagacgttc aaaattaaaa
    18961 tttggacgtc ttttttatta cccaaaaacg aaaggagatt tattttatga aaaagccaag
    19021 atttaagaat tggcgtttgc tcgcaacact gagtctatta tgccaaacaa ttggtggatc
    19081 gcttggccca acgattgcct ttgctgatga aattactcat ccacaaacgg taactgtgga
    19141 attggatttg gctcaccagt atgctgtcga aggtacattt agcgatggtc gtcccatgtc
    19201 agaagttacc gttccgcact atgcagttta caatggtgtg aagcaagata ttttctgtat
    19261 tgagccaggg gtgccgattt acaatgagtt cactcctggt tatgagaaaa atccattgcc
    19321 tgatatgtcg gagaaagcga aattagtttc cgttttatgg aaggaagctg gtacggatgt
    19381 ggatacacat attgtggccc agaagatgat ttggcaagaa gttaatggct acacgcttca
    19441 ctcaattaaa cgttctgatg gtagtgcagt aaatatcgca gccattgagt caaaaatcaa
    19501 tcaagccatt gcggattatc aaaagaaacc aagcttccat aactccacag tgaaaaccgt
    19561 gttaggtcaa tcgactactg tgacagatac gaacggcttg aatttatcgg agtttgatga
    19621 agttgtcgag aatatcgcaa atattgatta tcgtgtgaac ggcaatcaac tagtgattac
    19681 tccaaatgcc aattcaaaag agagtggtga attaacccta aagaagtcag ctaatacagg
    19741 aacaccggta gcttataaaa tggctggtca acaaactttg atggcggggg caattgataa
    19801 gcccaatacc tacacaatca aaattgatgt ggaaactgag ggttctttga agattaaaaa
    19861 agtcgataaa gaaacaggaa atgttgtacc gggaaccgtt ttccatttag actttggaaa
    19921 aacattacct gcaaaagacg tgaccaccga taaagaaggc attgcgacat tggatgagat
    19981 tcctcatggc gcgaaagtaa ccattactga aaaatcagtg ccagctcctt atacgattga
    20041 cactacacca atcaccgcaa ccattaaatc tggtgagact atttctgtga cttcaaaaaa
    20101 tactcgcgaa aaaggtcaaa tcattttgaa taaaatgggg gtggaaacag gaactgatct
    20161 ttggaacgac aaatactcat tagccggaaa tacgtttgcc attcgcaaag acagtccaac
    20221 cggtgaaatt gtccaagaaa tgaccacgga tgaaaaaggt catgcggaaa caccaaaaga
    20281 gattgccaat gcgttggaat tgggaaccta ttatgtgacc gaaaccaaag ctagtaatgg
    20341 ctttgtgaat acctttaaac cagtaaaagt cgaattgaac tatgtcaatc aaaccgtggc
    20401 tcttgttacc agtaacgtaa aagggcaaaa ccaagaaatc actggtgaaa ccactttgac
    20461 aaaagaagac aaagataccg gtaatgaaac tcaaggtaaa gctgagttta aaggagctga
    20521 atatactctc tttactgcaa aagatggtca agcggtcaaa tggagtgagg cttttaaacc
    20581 agagttagtg aagggaacga aagcttctga tgaaacggtg actttgactt tagatgaaaa
    20641 gaatcaagtt gctgttaaac acttagcgat taatgagtat tactggcaag aaaccaaagc
    20701 acctgaagga tataccttgg atgaaacaaa gtaccctgtt tccatcaaaa aggtggatga
    20761 taacgaaaaa aatgccgtga ttacccgaga tgttacggca aaagaacaag tcattcgctt
    20821 tggctttgat ttctttaaat ttgctggatc agctgctggg actgccgaaa ctggcttcaa
    20881 tgatctgacc tttaaagtat cgccattgga aggaaccagt gagattacag gtgccgaaga
    20941 tgaagcaatt acagcttata acgagcaact aggttttgat ggctatggca agtttgaaaa
    21001 tcttccttat ggggattatt tacttgaaga agtagaggct ccagaaggat ttcaaaaaat
    21061 tacgccatta gaaatccgtt ctacttttaa agaaaataaa gcggattaca ctaagagtga
    21121 atacattttt acgattaccg aaaaaggaca aaaacaacca attaaaacgg tgaccgttcc
    21181 ttacgagaaa ctgacgaata aagcattttc tgttagcttg aatcgtttga tgctctatga
    21241 tttacctgaa gaagaagata gcttaacttc tcttgggact tggaaagacg gaggcaaaga
    21301 attgacagac cttgattcta ccgagctagt tgataaattg agctataact tgcatgaaat
    21361 caaagaagac tggtatgtgg tagcgcaagc cattgatgtg gaagcgacaa aagctgccca
    21421 agaaaaagat gaaaaagcca aaccagtggt aattgccgaa acaaccgcaa cgttggcgaa
    21481 taaagagaaa acaggaactt ggaaaatttt gcataaatta accgcagaac aagttttgga
    21541 taaaaccatc gtcttattca actatgtgta tgaaaacaag aaaccctatg aagcaggtga
    21601 tgatccagta gcgaaagatg ctagcttgaa caatcaagcc caaactgtca attgtacggt
    21661 ggaacgccat gtttccatcc aaacaaaagc ccacctagaa gatggttcgc aaacctttac
    21721 tcatggggat gtggtggata tgttcgatga tgtgtcgatt acccatgatg tactggatgg
    21781 ctcaaaagaa gcttttgaaa caattctgta tgcattactt ccggataata cgaccaaaga
    21841 aatttggaaa tctggcaaaa ttgattatga agtgaatgac aaagaattca ctaaaaccgt
    21901 acttgcggaa aaagtggaca caagtaaata tccagaaggt acaagtttta ccttcaaaga
    21961 aattaactat ggcaaagacg gaaacatcaa tgggaaacac aatgaggatc taaaagaaaa
    22021 aactcaaact ttaacaccta aaaaagttcc gacaacacca agtgcaccag aacaaccgga
    22081 aataccaact gttccaagtg actctcaaga atctagtcct acagtaaaga cattcccaca
    22141 aacaggggag aaaaattcta atgttctgct gtttattggg tttaccttga tctttgcgac
    22201 tgctgggtat tatttctgga atcgccgaaa ctaaggtgat gtgatgaaac aactaaatag
    22261 gaaaaaccaa cgtgcgcgac cgcctcctaa aaaaagtggt cgcgctattt ttgtatccaa
    22321 aactaaaaat gaaaagagga aaagaagatg gaattgaaat ttgttgtgcc agatatggcc
    22381 gaaacctttg gaaagataag gtatgccggc gaaggcgaag ttttaactga aggatatggg
    22441 cggaatacta cagtaattgg tcgtagttat catttgtatt ccagtaagca acgagccgat
    22501 gatattgaag tggtggtagc tgcggaagcc ggcgaaaagg attttgatca agatcaacca
    22561 ctaaaagccg tgaatcccca tttggttgcc aaaggctatg agattgagaa tcgtgggttt
    22621 accgactacg tgttgtatgt cgatgattta gtgaaagcat aggaggaaaa gaagatgaga
    22681 ttaacagaag gtattgttgt agattcagga ctaacgtttg ggaaattacg attttccgca
    22741 ttacgccgag aagtacggaa gcaaaatgag gatggaacgg ttagtaacga ggtaaaagaa
    22801 cggacttata atttgaaatc ctctgcgcaa ggtcgaatga tccaagttag tatcccagca
    22861 aatgtaccct tacgcgagtt tgcctatgac gcagaggtag agttggtcaa tccaatcatg
    22921 gatacggtcg ccaattatgt tttccgagaa ggaactactg tcaattggtt cattaaggcc
    22981 gatgatttag tcttgaaacg acaaccagat cagggaaatt ctacaaacca aaatgaagga
    23041 aagaaatagg tgaagcgtat ggaaattaat gttgaacata ttttagattg tctcgatcaa
    23101 tatggaaaag gtgagctaac ggaggaacaa ctcactaaag cattaaccta tgatgaaaaa
    23161 atgtttctga ttatgcatca agggttactg gaagtaggta acgatgccga agaagatttt
    23221 gatgtactga attggttagg ggaagaagag tccttcttta tggttatcga agtaaatgaa
    23281 agtctatgtc gagaagccga aaccgtattg gaagaaattg gtgtggaaat gccggatgcc
    23341 attgaagttt ttttaaagca actagtggaa acgaaacaac tccctatagc agtaaatgac
    23401 tagcataact gcttgaaatt ggatcaatga aatcctatga agcttttttc gattggaggt
    23461 ggaaaccata aaaatgtaca aagggcatcg tatacgggca ggagatcagc acttggttta
    23521 tcactttgtt cttggctggc tactcgctct gttcatcggt tggatgagcg tcttttattt
    23581 tcaagagctt agacaatttg atatttctaa gctatcactt tctactatag aaatcgttcg
    23641 ttctataaaa gatttaatct atttgctagg aagtctcgtt ctttcaggaa gcacgatgtt
    23701 gctttatata cacttttttc aggatcattg gcgcagtttg tggcatcgac aaaagctagc
    23761 ccggatgatt ctagaaaatc attggtacga agtaaaacaa actcagagtg aaggattttt
    23821 caaagacctc aatagtagtc gaaccaaaga gacaatcagt tacttcccca aaatctatta
    23881 ccgtatgaag gatggtttac tttctattcg cgttcaaatt tcactgggaa aatatcaaga
    23941 tcagctttta aagctggaaa agaagttaga aagtggtcta tattgtgaac tagtagaaaa
    24001 ggaactcaaa gactcctatg tggagtacac tttactgtat gatataattg ccaatcgaat
    24061 tgggatagac gaagtagtgg cagaaagtgg ggctttgcga ttgatgaaaa atcaagtatg
    24121 ggcttatgat tctttacctc atatgttaat cgctggcggc acaggtggtg ggaagactta
    24181 ctttttactc actatcatcg aggctttatt aaaatctgat gccgagcttt ttgttcttga
    24241 tcccaaaaat gcggacttag ccgatttagg tacggtaatg cctcatgtct attcccaaaa
    24301 ggaggaaatt tctgcttgtg tggaagattt ctatgagcgc atgatgactc gtagcaaggc
    24361 aatgaaagaa atgcccaact acaaaacagg agagaattat gcgtttcttg gacttccacc
    24421 aaacttttta atctttgatg aatacgtggt ttatatggaa atgttaacga cgaaggaaag
    24481 tgcggtgatt ttgaataagc tcaaacaaat cgtgatgtta ggtcgtcaat ctggtttctt
    24541 tctgattcta gcttgtcaaa gaccggatgc gaaatattta ggagacggga ttcgcgatca
    24601 atgtgcgaca tgtttctaac tgaaaaggtt aggcacttaa aagaagaaaa cataagtttc
    24661 cttttaagga gaactgatat tttgagcagt ggaatgatgg ggtaacgccc tgaaacgctc
    24721 ccttaatact ccgactggct gtttaacata tagctgttag atggtcagaa gctcggtgaa
    24781 gtcggctgaa agttaccgta aatatgataa attcatatac gaaagttgtt cagaggtgaa
    24841 tgatgtaacc tataggtcgg aggtctataa aatactcacg gtgagaatgt aagtaatact
    24901 actgacgaac ttgcgaatga aagaatctat acacggactg tatagaaatg tacaggattc
    24961 taccgtatca acggaacaga atgtatgttg tggtttagta agattattgg ttatgaacaa
    25021 ccatgcaatg ttacaggcat tggaaatata caggttcaaa gcaagcacct aaaagtatat
    25081 ataaagataa aaatatcgaa acatgggaag ctggcaatgt ggaggaaact atattccatt
    25141 gaaacatttg tgacgaagaa taataagcac atttatgcca gtgaaagtgg tggcacagta
    25201 ccaatgagga tatagaaata tatcggagga atagccacta gtcaaaagaa atcgttaatt
    25261 aaatgatgta tttcatagaa tcgagtaaga caaaataaac actacaacct aagtaaacaa
    25321 aggtagtggt gctatgaata aagtaaaaac aaataaaaca cttcgtcata gtgaatacta
    25381 tggcatgaca caaatatttg atgaactgta tgtaaaaagt gataaaaaag aagtttttac
    25441 agagctcatg acaattatta tgagtgatga aaatattcga ctagcataca gaaatatcaa
    25501 gaataacaag ggcagttata cagcgagtac cgataagaaa agtattcgag acattaaaac
    25561 actgtcagaa gatacctttc taactgaggt taaagttctt tttcgctgtt acaaaccacg
    25621 agcagttaga cgtgtagaaa ttcccaaacc aaatggaaaa acacgccctc tgggcattcc
    25681 atcaatctgg gataggttaa tacaacagtg tattttacaa gtcttagaac cgatatgcga
    25741 agctaaattt cacaattata gttatggatt tcgaccaaac cgttccacac atcatgcgat
    25801 tgctacctgc aatcgactgg caaatagggg gaagctacac tttgtagtag atgttgatat
    25861 taaaggattc tttgataatg tcaatcactc taaacttttg cgtcaaatgt ggacgattgg
    25921 aatccgtgat aaatggctat taggtattat tcgatccatg ctaaatgctc ctatagtcct
    25981 accaaccggt aaagtcgaac accctaaaaa aggtgtacct caaggtggtg tcctatcccc
    26041 tttactatct aatatcatat tgaatgaatt agattggtgg gttgcttcac aatggcaaaa
    26101 taccacgatt gagacagaaa agattatgga taggcgagat aaaggcaaag gcattgataa
    26161 gactaatcag tatcgggcat taagacgaac aaacttaaaa gaaatataca ttgttcggta
    26221 tgctgacgac ttcaaaatct tttgtagaaa acgaagtcat gcagataaaa tatttcacgc
    26281 aacgaaaatg tggcttaaag aacggttatc acttgaaatt agcgaagaaa aatccaaaat
    26341 tgtcaatctc aaaaaaggta aatcagaata tctaggattt gaattaaagc taatcaagaa
    26401 aggtaaaaaa tacgtagtcg aaagtcatat gagcaaaaaa tcaatgacaa gagttaaaat
    26461 ccaattaaag aaacaattac gtaaagttgc cagaccgaag aatcattgcg aacaagcaaa
    26521 agaaattgga ttatataatt ctatggtgat tggaatccat caatattatg gaattgcaac
    26581 ctgtgtaaat ctcgattgca gtaaaatagc ctatacacta aaaccgttca tcaatcacaa
    26641 actgccgaca aagaaacatg gaaagatatt aaatacattt atcaaatcga agtatggaaa
    26701 aagtaaagaa atgcgatggt tgaataatgt gccaattgta ccgctcaact atgttcagtt
    26761 tagacttgct gtccccctat cagagggaac ttgcaagtac actgaaagtg gacgaagcaa
    26821 gatacacagt aaattaaaat tagacctagc ccttttactt cacatgatga gaaatagtaa
    26881 ttatgaaaga agtattgaat ttgtggataa cagaatatct aaatattctg ctcaaaaggg
    26941 aaaatgtgct atcacgggta aatttctcga atacgaagaa atccattgcc accatatcgt
    27001 accagtaaaa caacagggta cagacaaata cagcaacctc attattattc acaaaaatgt
    27061 tcacgcatta gtccatgcta tcgaagaaaa aatcatacac aaatacctga atgtattaaa
    27121 tctaaccaat gaacaaatag aaaaactaaa tgaattacgt gtcaaagctg gtaatagtgt
    27181 tttaacagtt taacttgaaa aatatatcat acttaacatt cttttgatgg aacgccgtat
    27241 gaagtgaaag tttcatgtac ggtgtgaagc gggggaaaat ctggagatga catcaaagga
    27301 ttacctatcg c
//
LOCUS       DAFBVQ010000032        27300 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.032, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000032 DAFBVQ010000000
VERSION     DAFBVQ010000032.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 27300)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 27300)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..27300
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.032"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(53..421)
                     /gene="rplL"
                     /locus_tag="LLC22_001585"
     CDS             complement(53..421)
                     /gene="rplL"
                     /locus_tag="LLC22_001585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356427.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L7/L12"
                     /protein_id="HBK5434867.1"
                     /translation="MALNIENIVAELKEATILELNDLVKAIEEEFGVSAAAPVAVAAA
                     GGAAAAEEQTEFTVELTAAGDQKVKVIKAVREATGLGLKEAKAVVDGAPAPVKEGVSK
                     EEAEELKAKLEEVGASVTVK"
     gene            complement(474..977)
                     /locus_tag="LLC22_001586"
     CDS             complement(474..977)
                     /locus_tag="LLC22_001586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L10"
                     /protein_id="HBK5434868.1"
                     /translation="MSEAIIAKKAAIVDEVSEKFTAAASVVVVDYRGLTVDEVTRLRK
                     QLRDANVEMKVIKNSILSRAAKKAGLEGMDEVFTGPTAVAFSNEDVVAPAKIMDEFAK
                     EAKALEIKGGIIEGKVSSLEEITALAKLPNREGLLSMLLSVLQAPVRNVAYAVKAVAD
                     KEDGDAA"
     misc_feature    complement(1181..1308)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00557"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L10 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00557"
     gene            complement(1387..2076)
                     /gene="rplA"
                     /locus_tag="LLC22_001587"
     CDS             complement(1387..2076)
                     /gene="rplA"
                     /locus_tag="LLC22_001587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L1"
                     /protein_id="HBK5434869.1"
                     /translation="MAKKSKKMQDALKKVDSSKVYPVAEAVALAKETNIAKFDATVEV
                     AYRLNVDPKKADQQIRGAVVLPNGTGKTQTVLVFAKGDKAKEAEAAGADFVGDDDMVQ
                     KIQNGWFDFDVVVATPDMMATVGRLGRVLGPKGLMPNPKTGTVTMDVTKAVNEVKAGK
                     VTYRVDKAGNIHVPIGKVSFDDEKLVENFAAIHDVLLKAKPSAAKGQYMKNVTITTTF
                     GPGIHVDQASF"
     gene            complement(2180..2602)
                     /gene="rplK"
                     /locus_tag="LLC22_001588"
     CDS             complement(2180..2602)
                     /gene="rplK"
                     /locus_tag="LLC22_001588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L11"
                     /protein_id="HBK5434870.1"
                     /translation="MAKKVEKIVKLQIPAGKATPAPPVGPALGQAGINIMGFTKEFNA
                     RTADQAGLIIPVVISVYEDRSFTFVTKTPPAAVLLKKAAKIEKGSGEPNKNKVAKVSS
                     DQVREIAELKMEDLNAANVEAAMRMVEGTARSMGITVE"
     gene            2945..3613
                     /gene="sdaAB"
                     /locus_tag="LLC22_001589"
     CDS             2945..3613
                     /gene="sdaAB"
                     /locus_tag="LLC22_001589"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent
                     subunit beta"
                     /protein_id="HBK5434871.1"
                     /translation="MKDLRYRSVFDIIGPVMIGPSSSHTAGAARIGKIIRSIFGEQPD
                     SVDIYLYESFAKTYRGHGTDIALVGGLLGMEPDDERLADSLKLAYEAGMEVLFVPKSE
                     KAEHPNSVKMLLKKGTRKLSVTGISIGGGNIQISELNGFKISLSMGTPTLIVVHQDVP
                     GMIAKVTSILSETNTNIGTMTVTRESKGENAIMIIEVDDPQVEETVKRLKQLPNIDSV
                     NYFD"
     gene            3626..4498
                     /gene="sdaAA"
                     /locus_tag="LLC22_001590"
     CDS             3626..4498
                     /gene="sdaAA"
                     /locus_tag="LLC22_001590"
                     /EC_number="4.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-serine ammonia-lyase, iron-sulfur-dependent,
                     subunit alpha"
                     /protein_id="HBK5434872.1"
                     /translation="MFLSIEELVDQAKAYPSVAELMIAVEMEMSGRSRSHIIEIMEKN
                     LSVMEQSINEGKEGVTSVTGITGGDAKKLDDYLNEADFLSGETILKAVRNAVAVNEVN
                     AKMGLICATPTAGSAGVVPGVLMAVRDRLDLTHEQQLEFLFTAGAFGLVIANNASISG
                     AEGGCQAEVGSASAMAAAALVCAKNGTPHQAAQAVAITLKNMMGLICDPVAGLVEVPC
                     VKRNALGSSQAFISADMALAGIESVIPPDEVVAAMYQVGRQMPSIFKETAEGGLAVTP
                     TAKRLAEEILNKRA"
     gene            complement(4589..5608)
                     /locus_tag="LLC22_001591"
     CDS             complement(4589..5608)
                     /locus_tag="LLC22_001591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha-hydroxy-acid oxidizing protein"
                     /protein_id="HBK5434873.1"
                     /translation="MEAGAFGYIRGGSEDEWTMKENTTSFNTKKIMPRILRGIDSADL
                     HTSVFGIELDTPIIQAPSAAQGLAHEKGEADTAKGVAAAGSIFSISTYANTTIKDAAD
                     AAPGAPQFFQLYMSKDDRFNEFILNKAVEAGAKAIILTADSTLGGYREEDVINQFQFP
                     LPMPNLAAYSEQSASGNGEGKGIAEIYAAAKQGLTPDDIKTIKEITHLPVIVKGIQSP
                     EDAVIAISAGADGIWVSNHGGRQLDGGPASFEVLPKIAEVVNKRVPVIFDSGVRRGEH
                     VFKALASGADLVAIGRPVIYGLNLGGAEGVTSVFEHLNKELSITMQLAGTKTIDEVKN
                     TKLMD"
     gene            complement(5781..6686)
                     /locus_tag="LLC22_001592"
     CDS             complement(5781..6686)
                     /locus_tag="LLC22_001592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318099.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5434874.1"
                     /translation="MERKRCMTEPIKNLCKRATAAALVLISLFALSGCQTTKINTTEV
                     SDKEKTAESSKVIEKTTIPTLFFHGYSGTENSFKGMLRRLEKNQQAVKELVLTVGTDG
                     QIQATGDLSGKADNPMVQVLFEDNKNNEWNQAEWIKTCLLYLKENYGIDKVNIVGHSM
                     GGVSALRYLGTYGQDTSLPQVQTLTAIGAPFNDFVDDSAQSLTDELAKGPAVVSNRYQ
                     DYQQMIGNIPITTRFFLIAGQLDETDLSDGTVPLNSALAVYALLKQRGNEIEEKVVTG
                     ENASHSMLHENQEVDQLVSRFIWKE"
     gene            complement(6745..7290)
                     /gene="nusG"
                     /locus_tag="LLC22_001593"
     CDS             complement(6745..7290)
                     /gene="nusG"
                     /locus_tag="LLC22_001593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusG"
                     /protein_id="HBK5434875.1"
                     /translation="MESFEKNWYVLHTYSGYENKVKANIESRAQSMKMADFIFRVVVP
                     EEKETEVKNGKEKEIVHKTFPGYVLVEMIMTDASWYVVRNTPGVTGFVGSHGAGSKPA
                     PLLPEEVNHILRSIGMSLRQNDLEVEVGEVVKIIEGAFAGLEGQVTEVDGEKEKLKVN
                     IDMFGRETSTELDFDQVDKID"
     gene            complement(7391..7561)
                     /gene="secE"
                     /locus_tag="LLC22_001594"
     CDS             complement(7391..7561)
                     /gene="secE"
                     /locus_tag="LLC22_001594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722316.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecE"
                     /protein_id="HBK5434876.1"
                     /translation="MKFLKSVKDEIKQVTWPSRKQLRKDTLVVIETSIIFGLMFYVMD
                     TAIQSLFGWILK"
     gene            complement(7585..7737)
                     /gene="rpmG"
                     /locus_tag="LLC22_001595"
     CDS             complement(7585..7737)
                     /gene="rpmG"
                     /locus_tag="LLC22_001595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBK5434877.1"
                     /translation="MAKKKAALACSVCGSRNYTKSVSEGKSGERLEINKFCKYCNQYT
                     LHKETK"
     gene            7899..8543
                     /locus_tag="LLC22_001596"
     CDS             7899..8543
                     /locus_tag="LLC22_001596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5434878.1"
                     /translation="MLLKTLVYKKKDLTTVTETSTLEEALKILETSGYRCVPILDSSG
                     NIFRGNIYKMHIYRHKANGGDMTLPVTHLLKNATKFIYLDTSFFKVFFTIKELPYIAV
                     LDSENHFYGILTHSTLLNMLSQSWSVEQGSYVLTIASTGKQGDLAAIAKIISKHSSIA
                     SCITLDIEKDEYIRRTLITLPANTEAKVCETIVNHLEKKNYKVVEIENLQNQEA"
     gene            complement(8599..9102)
                     /locus_tag="LLC22_001597"
     CDS             complement(8599..9102)
                     /locus_tag="LLC22_001597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBK5434879.1"
                     /translation="MQKTKSRQRLSVIVVNGIIMALYLALTILVAPVSSGPIQFRISE
                     SLNHLVVFNRKLLWGVLGGVIVYNAFFGFGIMDVVFGGGQTLLSLGLTALLQNKVKNV
                     KMRLVLNTIFFTISMGLIAYMLVPTGGQAFWTTYGTLALSEFIVMAVSAPLMYYLDRA
                     LDFEKRV"
     regulatory      complement(9115..9161)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            9699..10664
                     /locus_tag="LLC22_001598"
     CDS             9699..10664
                     /locus_tag="LLC22_001598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBK5434880.1"
                     /translation="MKFHYHILINPSAGSGNGYKVAERILPVLKNKHIDYTLHYSEYK
                     GHDAEIAETLAKETLIPWIEEEQKTIDTFPLLIIVGGDGTLHQVLDTFYQMEVEFPVA
                     YIPAGSGNDFARGAGLPKNPKKGLQLILAAQSPEKVHIMAYEEKISEKKGIAVNNFGI
                     GLDAAIVHATNHSSTKKRLNKYNLGSFSYLFSILRALFTQKGFPILVDAGGKQLSFSN
                     AFLCTATKHPFFGGGIAIVPTADASKPVIDFVVVERINFFKILWLILLLIQKKQLKSK
                     YFHHYTTNRLRIVSTTPQHGQEDGEEMEKRPFDITITTTKQLFWC"
     gene            complement(10763..11935)
                     /locus_tag="LLC22_001599"
     CDS             complement(10763..11935)
                     /locus_tag="LLC22_001599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434881.1"
                     /translation="MTLYKTIWTLLKANKSNLLIGVIITVVATFFFAQNIDVENTSLQ
                     DAKIALISEEESPVVDGLRKYLNDKETVVTLDGTSQKEIDDALYFNRVNIILHLPADF
                     TEQVEVGKMATIKIQSRPDAFSKTVVTQQVNTFLQTLILFQEEDKTIDAAMEQTQMAL
                     SVTGEVELSAGYSQRMKKLLTGTTFNFLSYGLFLSIFSGFSVINLAFNRKEISKRNQS
                     APITKRNLNRKVTFSLISYSLLLFSGFLLLMVLLVIHTSWDITVWYHILNTFLFLLPI
                     ISFSACITSLVKNSETSGGIKDIFITGSCFIGGVFVPAEYLPEMVSKIAAFTPTYWFV
                     QNNNLISETLSYNQTFAESFWFNGCVLVAFAAVFSMIQFILGKERNYRWQPNWAKN"
     gene            complement(11922..13067)
                     /locus_tag="LLC22_001600"
     CDS             complement(11922..13067)
                     /locus_tag="LLC22_001600"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434882.1"
                     /translation="MFWHFYKYRTKILLRNKSMLFWTLAFPILLGLMFMAAFGEIDQG
                     GNLETINTGIVIKADQTALSENFTTVLEQVEVNDKPLFEVQELSEVEANEKLNADDLA
                     GFYLIDGSSVSLHVGQAGMSQTLMKNVMDQFLQRIGIISSKVAEVENVDLAPIMTVFE
                     QEVSFQEVHAGRNMSFKSFYFFTLIGMAILYGTMWGVRNVQDQQANQSSNGIRLSLIP
                     RKQSLVSIANLAASFTIVLTEIYIMLAVFRFIYQVDFGERWQWLMIVTALGSLCAILL
                     GTLVGNLIPKMNLVQKDSILISVTIAMSFFAGMMGSEQVKYWIDLHIPIVGQLNLVNL
                     ISESLYKLYFYTDLASFYTNLLWLIGFIFLFALGNAWMERGVRYDAL"
     gene            complement(13081..14013)
                     /locus_tag="LLC22_001601"
     CDS             complement(13081..14013)
                     /locus_tag="LLC22_001601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015509966.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434883.1"
                     /translation="MIIEIDKLVKRYGDFVALNHFDLQVQEGEVLGLLGPNGSGKSTA
                     INCMLSLLNYDKGTIKLFGTTMTPENYAVKAMIGVVPQDVAVFDELSVQENIDYFCGL
                     YVSEKEKRKALIEEVIQLVGLEKYVSFRPGELSGGLKRRLNIACGIAHKPRLIFLDEP
                     TVAVDPQSRNKILESIKELNRQGATIVYTTHYMEEVEILCDQIVIMDQGQVIAKGTKE
                     SLKDMVRTADRLTIDIPLLPENVLSAIQRTIASDGIAYKKGQLQVTTTELNTVLLPIL
                     TILQEEKISYGKIATKEASLNDVFLEITGKDLRD"
     gene            14130..15209
                     /locus_tag="LLC22_001602"
     CDS             14130..15209
                     /locus_tag="LLC22_001602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK5434884.1"
                     /translation="MHKSRLLNETSFLLVISLLLLVSQGFVAMQVIYLLIAVLFTGVS
                     YLLPTKPNWIFQVILFLLCAFLPDLVLFLPATMRVIAPEESHLDYLFLLGFLLISTVG
                     NHPPIKVAFVVILLFFSFYLRKKDQRTTDLEKKYIVSKDTHWEKQQELSEQNKALALS
                     QETQLALQIVEERNRIARDIHDNVGHLLSSAILQIGALEMINQEPKLKEPLENLSATV
                     HTGMDRIRQSVHDLHETSISFQHSLEFLIADFPSSVTIEGNLFEGLNETQQNCFLMVI
                     KEALTNSIKHSHAKTVVLHFRTLPAFYRLQITNDGTSPQKNSAPGIGLKTMRQRVQEQ
                     KGQVHIFQENQQFQLTIILPREGHQ"
     gene            15206..15835
                     /locus_tag="LLC22_001603"
     CDS             15206..15835
                     /locus_tag="LLC22_001603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325326.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5434885.1"
                     /translation="MITVVIIDDDPFVTKSLQTILESTKEIRVLGIGHCAKDALVLYE
                     THRPDVLLTDIRMPKQTGIDAAKEILAKFPKAILLLLTTFKDEEYIREAFSIGVKGYL
                     IKQNLQAIIPSVKSAYNGQAVFGNEIIETFTQMMKNKPTIDSHAYASFSERELAIIKE
                     VAAGKNNKEIADALYLSDGTVRNYISQLLEKLDLRDRTQLAIYFYQHLQ"
     gene            complement(15945..16172)
                     /locus_tag="LLC22_001604"
     CDS             complement(15945..16172)
                     /locus_tag="LLC22_001604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5434886.1"
                     /translation="MAKETEDKLAKLAKESGNDFKKLDEMEKEFKLNESPDVERDDRE
                     ESKLEKTLDKAPIFPPNTPNNPTNPGSPANP"
     gene            complement(16275..18863)
                     /locus_tag="LLC22_001605"
     CDS             complement(16275..18863)
                     /locus_tag="LLC22_001605"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent RecD-like DNA helicase"
                     /protein_id="HBK5434887.1"
                     /translation="MQPEEMPYFVGTVAAIFFQNPSNFYKVLLVHISETTADYREKEI
                     VVTGSFGDIQENETYRFYGELVDHPKYGRQLKLERYEQEKPTTANGIVAYLSSEKFPG
                     IGKKTAEKIVELLGEDAIEKIIADPSVLKQISGLTKPKREMLAETIRLNHGMDQVIMG
                     LNRYGFGSQLAFSIYQAYKNESLDIIEENPYQLVEDIEGIGFKRADNLAEQIGIAADS
                     PRRIRAAILHQIFQHAVQTGDTYVPAETLLQQTIRILETSRPIEIQPDQVATVIIQLV
                     EEGKIQQEETNLYENSLYFSEWGIGNSIQRLLSRKKEIHYPEKEVQKNIRRIEKIFGI
                     QYGPSQEQAIAEAIRSPLFILTGGPGTGKTTVINGIVNLFAELNGLELDPSKYTQEIF
                     PILLAAPTGRAAKRMNETTGLPASTIHRLLGLNGREKTPSVSTKELEGGLLIVDEMSM
                     VDTWLANTLFKAIPTNMQVILVGDKDQLPSVGPGQVLHDLLEIEQIPKMELNQIYRQG
                     DGSSIIPLAHEIKEGRLPKDFTKNQKDRSYFRSDAYQIEPLISKIVEKAKNKGFRAQD
                     IQVLAPMYRGPAGIDALNKMMQEIFNPGKPGKKEVHWNDTVYRIGDKVLQLVNTPELN
                     VFNGDMGEITGIILAKDSEDKVDELVIQFDANEVTYKRNEWNKITLSYCCSIHKSQGS
                     EFKMVILPMVHQYQRMLQRNLLYTAVTRSKELLILLGEEQAYVTCVANESASRMTTLK
                     SRIMDNDKMNITLRTKLAAYEDSLVGNDPFEDGNYTKEPRVVKEKLPVEDDSGTNETK
                     NQVMETVEPDLFSSFVGEEKKEEVEPAVSKDFVLTAEVIDNQLVDPMIGMENSSPYDF
                     IPAKNA"
     gene            complement(18883..19542)
                     /locus_tag="LLC22_001606"
     CDS             complement(18883..19542)
                     /locus_tag="LLC22_001606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5434888.1"
                     /translation="MELYFTRHGKTQWNQERRFQGSNGDSPLLPQSYEEIKAFGKKVK
                     YVPFKAIYSSTAKRARDTAEGINKELARPVEIFYTDKLRELGLGTLEGQSIDEMYQKY
                     PDNLPNLRNHLDLYDPSPFHGETIESAITRIETVVADAVARHKDGPLLFVGHGASLTA
                     AIQWMTGKELSELREMGGLFNSSLTILETEEPCRLLPYELKVWNQTDFLGTETAPEPL
                     L"
     gene            complement(19591..20094)
                     /gene="trmL"
                     /locus_tag="LLC22_001607"
     CDS             complement(19591..20094)
                     /gene="trmL"
                     /locus_tag="LLC22_001607"
                     /EC_number="2.1.1.207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (uridine(34)/cytosine(34)/5-
                     carboxymethylaminomethyluridine(34)-2'-O)-
                     methyltransferase TrmL"
                     /protein_id="HBK5434889.1"
                     /translation="MNHIVLFEPLIPANTGNIARTCAATNTPLHLIEPLGFSTDDKHL
                     KRAGLDYWNDVNITYHSNLEAFLTFLGNRKLHLISKFAHKVYSDENFADGEEHFFLFG
                     KETTGLPETFMRENEEKCLRIPMNDEHVRSLNLSNTAAMIVYEALRQQGFPNLELTHH
                     YENDKLD"
     gene            complement(20315..21181)
                     /locus_tag="LLC22_001608"
     CDS             complement(20315..21181)
                     /locus_tag="LLC22_001608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5434890.1"
                     /translation="MLKKIDRGRQFLAENHQLFRCPVCQEEVKKSDNGLICKNNHRFD
                     LSKKGTLYFLSHAVKTEYDQGMFVPRRRMIQSGMYQPVIETIAQHLPEEVSLLDVGCG
                     EGSFLNELSKLKKIQNAVGFDISKEGVYAATEQSAEAFWCVADLTNLPFADQTFNAVL
                     NIFSPSHYQEFQRVLSEDGEVLKVVPQENYLKELRQAFYPNQPEKQSYSNERVVAKFA
                     EAMKLTERQRVTYEFEIPEENQKDLLAMSPLEWQVEERIKADLYKNPLKKITIDIELL
                     KGTKRKRFSSSF"
     gene            21290..21931
                     /locus_tag="LLC22_001609"
     CDS             21290..21931
                     /locus_tag="LLC22_001609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper homeostasis protein CutC"
                     /protein_id="HBK5434891.1"
                     /translation="MIKEFCAENYTSIPLAIARGADRIELCDNLAVGGTTPSTGVIEE
                     TLSYAGEKDIPVMTIIRPRGGDFVYNDIELKIMHTDLIEAKKLGTDGVVFGCLTPSGW
                     LDEEALELLIETAEGLQITFHMAFDSIPEDRQFEAIDWLVEHGVDRILTHGGPADKTI
                     VENFPRLKELIAYTDGRLIILPGGGVTAENAAHVAKELNVSEVHGTKIVDLQL"
     gene            complement(21993..23354)
                     /gene="mgtE"
                     /locus_tag="LLC22_001610"
     CDS             complement(21993..23354)
                     /gene="mgtE"
                     /locus_tag="LLC22_001610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294561.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter"
                     /protein_id="HBK5434892.1"
                     /translation="MDENQELEERFAQLTQDLRENNIQAFRNSFLEMHIYEQGQFYQS
                     LTEENRQLIYSYLSPKELADMFDVIEEDNEHMKEYLDEMRPSYAADMLSEMYTDNAVD
                     LLNTLDKKQIAKYLSLMSADDASEIKELLHYEDETAGAIMTTEFVSIVANQTVRSAMY
                     VLKNEADVAETIYYIYVVNQEGQLVGVISLRDLIVNDDDAMISDLMSERVLSVHVGDD
                     QEDVAQTFRDYDFLALPVTDYDDHLLGIVTVDDIIDVIDDEAASDYSGLAGVNVEEIN
                     ENPVKAASRRLPWLITLLFLGMSTASLISHYEDLVSEASILAVFISLITGTAGNAGTQ
                     SLAVAVRRLAISDEKDHGFVRLVLAEVLTGVVTGAVTGITIFLIVGFWKHNFILGFVI
                     GMAMLFAITVANLAGSLIPMLMDRLGFDPAVASGPFITTLSDLTSVLIYFNIASLFMG
                     YFM"
     gene            complement(23372..24271)
                     /locus_tag="LLC22_001611"
     CDS             complement(23372..24271)
                     /locus_tag="LLC22_001611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RluA family pseudouridine synthase"
                     /protein_id="HBK5434893.1"
                     /translation="MQFTWDYEKDHSQQVKYFLKEKGISKGLLAKIKFQGGQIKVNDQ
                     VENVLFSLAKDDKVTIVIPAEGEHETVLLDETPIDIVYEDEHVLVVNKPAGVSSIPAQ
                     YHPNGTMANRVKAYYKKQGYENQVIHVVTRLDRDTSGLMLFAKHGFAHAKLDMQLREK
                     KFVKKYQALVSGRLSDLSAHGHIDLPIARDYSSLLKRMVSDEGRSAQTEYWIEKRLTE
                     IALVDIQLHTGRTHQIRVHFSAIGCALLGDDMYGGRMDLGIKRQALHCYDLRFYHPFT
                     EELLEFKQPLAADMEAVVRRFEE"
     gene            complement(24273..25070)
                     /locus_tag="LLC22_001612"
     CDS             complement(24273..25070)
                     /locus_tag="LLC22_001612"
                     /EC_number="2.7.1.23"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD kinase"
                     /protein_id="HBK5434894.1"
                     /translation="MKVAIVHNKEAKTIEVTERLNALLEQAGIQRDDHEPELVISVGG
                     DGTLLSAFHHYSHCLNDVRFLGVHTGHLGFYTDWRDYELEELVDSLRTNREQSVSYPL
                     LDVRISYLDETPDQHFLALNESTIKRANRTMVADVYIKNELFESFRGDGLTISTPTGS
                     TAYNKSVGGAVIHPSINAFQLAEIASLNNRVFRTLGSPIVIAHDEWLEIKLENTEDYL
                     VTVDQLNVAKANIRSIYYRIAEERIHFASYRHMHFWHRVKDAFISED"
     gene            complement(25048..25752)
                     /locus_tag="LLC22_001613"
     CDS             complement(25048..25752)
                     /locus_tag="LLC22_001613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289848.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP pyrophosphokinase family protein"
                     /protein_id="HBK5434895.1"
                     /translation="MERDWEAFLAPYEQTVSELKVKLRGIRKQFREQNRHVPIEFVTG
                     RVKPVDSIVTKSQLRHIPMGRLEEEMSDIAGLRIMCQFVEDIHQVVEIIRKRKDMKVL
                     QERDYITNKKASGYRSYHLVIEYPVQLISGEKKILAEIQIRTLAMNFWATIEHSLNYK
                     YQGVFPEEMSERLQRAAEAAYQLDEEMSSIREEIQEAQRLFSHGRGKSDDVYYRTLLK
                     KESEREEAGDESSDRS"
     gene            25883..26458
                     /locus_tag="LLC22_001614"
     CDS             25883..26458
                     /locus_tag="LLC22_001614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CYTH domain-containing protein"
                     /protein_id="HBK5434896.1"
                     /translation="MTQMLEIEYKSMLTKQEYEIFIAHYQLTDKDFRVQTNIYFDTVD
                     EQLKKQNCGLRIRFVGHQAEYTLKTPAEKGRLETTDTFITEEAEAFIFEKRLPRSGAV
                     FQKLSDLNIDPASLIQTGKLTTKRAEFPIEEGLLAIDESWGDNLHDFELELEVRDASV
                     GKIAFINFLKRFSLPYRPAKNKIQRMLEAKN"
     gene            26576..27253
                     /locus_tag="LLC22_001615"
     CDS             26576..27253
                     /locus_tag="LLC22_001615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBK5434897.1"
                     /translation="MIEIYLFVNPLGEYCFEMEQQLLQFIEEEYGTPSKEKMQFRFLP
                     LVNLQTIGDVMQQKGISQNNLEERNHLFSMTYSAALDCKAAQFQGKKKGRRFLIKLQE
                     AVGCNDIPYSQELAESIFEEIGGDLNMFKEDRQSDFVKEVFFSDQKIAREMGITKHPS
                     AVVYNYACDRDFGVLVEVKGTSSLWRITELCKTTDNSYQVFNGEHLHTNDSQFHSRTS
                     HLHLLSN"
BASE COUNT         7959 a         5758 c         4919 g         8664 t
ORIGIN      
        1 aaaaaagcac cgaaatccaa cataggatct cagtgctttt aaatagtaaa aattatttaa
       61 cagttacaga tgcgccaact tcttcaagtt tagctttcaa ttcttcagct tcttctttag
      121 atacgccttc tttaactggt gcaggagcgc catcaactac agctttagct tctttcaagc
      181 ctaaaccagt tgcttcacga actgctttga taactttaac tttttggtct ccagctgcag
      241 ttaattctac agtgaattct gtttgttctt cagcagcagc agcgccacca gcagcagcta
      301 cagctacagg agcagcagca gatacgccaa attcttcttc aatagcttta actaggtcgt
      361 taagttctag gatagttgct tcttttaact cagcaacgat gttttcaatg ttcaatgcca
      421 ttataatttc ctccgtttaa ttgttctttt ttatttaatg ctttatgcgg caattaagct
      481 gcatctccat cttctttgtc tgccactgct ttgacagcgt aagccacgtt gcggactggc
      541 gcttgtagta cagatagcaa catagataga agtccttcgc gatttggcaa ttttgccaat
      601 gctgtgattt cttccaatga agagacttta ccttcgatga taccgccttt gatttctaat
      661 gcttttgctt ctttagcaaa ttcgtccatg attttcgctg gtgcgactac atcttcgtta
      721 ctgaatgcaa cagctgtagg tccagtgaat acttcgtcca tgccttcaag gccagctttt
      781 ttagctgcac gtgaaagaat agaatttttg ataactttca tttctacgtt agcatcacga
      841 agttgtttac gtaaacgtgt tacttcatca actgttaatc cgcggtagtc aacgactact
      901 actgatgcag ctgctgtaaa tttttcgctt acttcatcaa cgattgctgc tttttttgcg
      961 ataattgctt cactcatttt tgagtttcac ctcctgaatt ttgatggaag agttttttgc
     1021 actgaaaagg caagtcactt ttatagttac tttgctcaac cagtattatt catcacctat
     1081 tcacttcgtt catagtgatt ctactcgctt tgctcgaaag gaaactcctt tcgctttgct
     1141 caaccagtat tgttcatcat ctcttcactt cgttcatagt gattcacaat aaaaaactct
     1201 atgccaccgc agacatagag ggactattga atatattcaa taaacgtcct cggtaggaaa
     1261 ttaaggcttg atgccaccta ctgtcttcgg tacaagttaa ttattaacct caactagctt
     1321 agcatgctaa actagttgag tcaagaatta tttttcagtt ggatcaatca acattctaat
     1381 atttaattag aaagaagctt ggtcaacatg gataccaggt ccaaatgttg ttgtgatcgt
     1441 tacatttttc atgtattgac ctttagctgc tgatggttta gcttttagca atacatcatg
     1501 gattgctgca aagttttcaa ctaatttttc atcgtcaaat gaaacttttc cgattggtac
     1561 atggatattt ccagctttgt ccacacggta agttacttta ccagctttca cttcgtttac
     1621 tgcttttgtt acgtccattg taactgtacc agttttaggg tttggcatta agccttttgg
     1681 tcctaatact cgtcctagac gacctacagt agccatcata tcaggtgttg caacaactac
     1741 atcaaagtca aaccatccgt tttggatttt ttgaaccatg tcgtcgtcac ctacgaaatc
     1801 tgcaccagct gcttcagctt cttttgcttt gtctccttta gcaaaaacta aaacagtttg
     1861 tgttttacca gttccgtttg gtaatacaac agcaccacgg atttgttggt ctgctttttt
     1921 agggtctacg ttcaaacggt atgcaacttc aactgttgca tcaaattttg caatgtttgt
     1981 ttcttttgct aaagctactg cttcggcaac aggataaact ttacttgaat caactttttt
     2041 taatgcatct tgcatttttt tgctcttttt agccattttg gttcctcctt gattgtggtt
     2101 ataacggttg tacctcccac gtgttctata tctttcaata tagagccaac tgagaagctg
     2161 ctgtcttagg gtgtatagat tattctacag tgatccccat gcttcgtgca gttccttcaa
     2221 ccatgcgcat tgctgcttca acgttagctg cgtttaggtc ttccattttt aattcagcga
     2281 tttctcttac ttgatcgcta gaaactttcg caactttatt tttgtttggt tcgcctgaac
     2341 ctttttcgat tttagctgct tttttcaata gaacagcagc tggcggtgtt tttgtaacga
     2401 atgtgaatga acggtcttcg tatacagaaa taacaaccgg aatgatcaaa cctgcttgat
     2461 cagctgtacg agcgttgaat tcttttgtga atcccatgat attgataccc gcttgaccta
     2521 gtgcaggacc tactggtgga gctggagttg ctttacctgc aggaatttgc aatttaacga
     2581 ttttttctac tttctttgcc acgagacata cctccttaag tccgtgatgt ggttaattgg
     2641 agatgcatat ttctcctccc acgttttatc tgatctgaaa aaatccagac aaataatgtg
     2701 caaaacaatg cacactggta cagtatagca aatttatttg ttttttcaag atttttttct
     2761 gctattttta cattttgctt gaataaacgc taaatttatt ctaaaaaaac aacaattttt
     2821 cgttctcatt tcttctttta tgttacactt gcgctagcat ggttcaacag atgaaagcaa
     2881 acaataacac ggttttttag acccttgtac aaagattcct acataacaaa atgaggtgga
     2941 gaaaatgaaa gatttaaggt atagaagtgt ctttgatatt attggacctg tgatgattgg
     3001 tccaagtagc tctcacactg ccggagctgc tagaatcggg aaaatcatac gtagtatatt
     3061 tggcgaacag cctgattctg tagatattta tctatatgaa tcatttgcaa aaacctatcg
     3121 ggggcacgga acagatattg cattagttgg cggcctgtta gggatggaac ccgatgatga
     3181 acgtttagct gattctttga aattggcata tgaagccggt atggaagtct tgtttgttcc
     3241 taagagtgaa aaagccgaac atccaaactc tgtaaagatg cttctaaaaa aaggaacacg
     3301 aaagctttca gtcactggca tttcgatcgg cggtggcaat atccagattt ctgaattgaa
     3361 tggattcaaa atttctttaa gcatgggtac tcctaccttg atcgttgtcc accaagatgt
     3421 tccaggtatg attgctaaag tgactagtat actttctgag accaatacga atatcggcac
     3481 tatgacagtg acacgggaat caaaaggtga aaatgccatt atgataattg aagtagatga
     3541 tcctcaagta gaagaaacgg taaaaagact caaacagctg ccaaatatcg acagcgtaaa
     3601 ttatttcgat taaggagcta aaaaaatgtt tttatcgatt gaagaattag tagatcaagc
     3661 aaaagcttat ccaagtgtag cagaattgat gattgcagtt gaaatggaaa tgagtggccg
     3721 ttcccgtagt cacatcatcg agatcatgga aaaaaacctc tcagtaatgg aacaatcaat
     3781 caacgaggga aaagaaggtg ttacctccgt cacaggaatt accggtggtg atgcaaaaaa
     3841 attagatgat tatttaaatg aggcagactt tttaagtgga gaaacaatct taaaagctgt
     3901 acgcaatgct gtagctgtta atgaagtcaa tgcaaaaatg gggttgattt gtgctacacc
     3961 gactgccgga agcgcgggtg ttgttcctgg tgtgctgatg gctgtccgag atcggcttga
     4021 tttgacacat gaacagcaat tggaattctt atttaccgct ggcgctttcg ggttagtcat
     4081 cgcaaacaac gcttctatca gtggtgcaga agggggatgt caagcagaag ttggttctgc
     4141 aagtgcaatg gcagcagcag ctttggtttg tgcaaaaaat gggactcctc atcaagcagc
     4201 acaagcagta gccattacat tgaaaaatat gatgggactg atttgcgatc ccgttgcagg
     4261 cttagttgaa gtcccgtgtg tcaaacgtaa tgctttaggc tcttctcaag cttttatctc
     4321 tgctgatatg gcattagcgg gtatcgaaag tgtcattccg ccggatgaag tcgttgctgc
     4381 aatgtaccaa gtcggacgtc aaatgccgtc gattttcaaa gaaacagcag aaggtggctt
     4441 agctgttacg ccaactgcta aacgacttgc ggaagagatt ttaaataaga gggcgtgata
     4501 aagctcctta atttcgagta ttaagagatt agttatcttc ataacaaaaa acgaagagag
     4561 gactaattgc ccttctcttc gttttttatt aatccatcaa tttcgtattt tttacttcat
     4621 cgatcgtttt tgttcctgca agttgcatcg tgatcgacaa ttctttgttc aggtgttcaa
     4681 aaacagatgt tactccttct gccccaccta gattcaaccc ataaatcact ggtcggccaa
     4741 tcgcaactaa gtcagcacca cttgccagag ctttgaagac atgctctcct cgacggacac
     4801 cagagtcgaa aatcactggt acacgtttgt tgactacttc ggcaattttt ggcaatactt
     4861 caaaggacgc aggacctcca tctaattgac gtccaccatg attggatacc cagataccat
     4921 ctgcccctgc agagatagcg attactgcat cttctggcga ttgtattcct tttacgataa
     4981 ctggaagatg ggtgatttct ttgattgttt tgatgtcatc tggtgtcaag ccttgttttg
     5041 cagctgcata aatttctgcg attccttttc cttcgccatt accacttgca ctttgttcgc
     5101 tatacgcagc taagttaggc attggtaatg gaaattggaa ttgattgatg acgtcttctt
     5161 cacggtaacc accgagcgtt gaatctgccg ttaaaatgat agctttagcc cctgcttcta
     5221 ctgctttgtt caaaatgaac tcattgaatc tgtcgtcttt actcatatat aattggaaaa
     5281 actgcggtgc gcctggcgct gcatcggctg cgtctttgat tgtcgtattt gcataagtgc
     5341 tgatggaaaa gattgatcca gcagcagcta ctcctttagc tgtatcagct tccccttttt
     5401 catgtgccaa tccttgggcc gctgatggcg cttggataat cggtgtatct aattcaattc
     5461 cgaaaacaga tgtatgcaaa tcggctgagt cgattccgcg taatatccgt ggcatgattt
     5521 tctttgtatt aaaagaagtc gtattttctt tcatcgtcca ctcatcttca gaaccaccgc
     5581 gaatatagcc aaaagctcct gcttccatgc gctcttttac acgaccttct agttaggcaa
     5641 tgtttacaat atcgattgga tgttcttcat tacttgtatg ataagtcata gtagatcctt
     5701 ctttcatctt cttgattaca tataaatcat actaaactta caaaaagtaa gcaaacattt
     5761 actctcagat acttttatcg ctattctttc caaataaatc gacttacaag ctgatctact
     5821 tcttggtttt catgaagcat actatgagag gcattttcac ctgtcactac tttttcctct
     5881 atttcatttc cgcgttgctt caacaacgca tagaccgcta atgcactgtt taacggtact
     5941 gttccatcac tcaagtctgt ttcatctagt tgaccagcaa tcaagaaaaa tcgagtggtt
     6001 ataggaatat taccgatcat ttgctggtaa tcttgatagc ggttagaaac gacagcaggc
     6061 ccctttgcta actcatctgt cagagactgc gcactatcat cgacaaaatc attaaaaggc
     6121 gcgccaattg ctgttaatgt ctgaacttgt ggcaatgacg tatcctgtcc atacgttcct
     6181 aaatagcgta gtgcactaac tcctcccatg gaatgcccca ctatgttgac tttatctatg
     6241 ccgtagtttt ctttcagata caaaagacaa gttttgatcc attctgcttg attccactcg
     6301 ttatttttat tatcttcaaa caatacttgg accatcggat tgtctgcttt tccagacaaa
     6361 tctcctgttg cttgtatttg tccatctgtt cctactgtta aaaccaattc ttttactgct
     6421 tgctgatttt tttccaaacg ccgcaacatc cctttaaagg aattttctgt cccgctgtag
     6481 ccgtggaaaa aaagtgttgg aatagtggtt ttttctatca ctttactgga ttctgccgtt
     6541 ttttctttat cagaaacttc agtagtattt atcttcgtcg tctggcaacc acttaacgca
     6601 aacaaactga taaggactaa agctgctgca gttgcacgtt tgcataaatt tttgattggt
     6661 tctgtcatac acctcttcct ttccatatag aaaaaagaaa gacttgaaag gccaatcata
     6721 tgatcgacat ttcaagtctc tttattaatc gattttatct acttgatcga aatcaagttc
     6781 tgtactggtt tcacgtccaa acatatcgat gttgactttc aatttttctt tttctccgtc
     6841 aacttctgtt acttgtcctt ctaatccagc aaatgcgcct tcgatgattt tcacgacttc
     6901 gccaacttct acttctagat cattttgtcg caggctcata ccgatagaac gcaagatatg
     6961 attgacttct tctggaagta atggtgctgg tttgcttccg gctccgtgtg aaccaacgaa
     7021 tcctgtcaca ccaggtgtgt tgcggacaac ataccatgaa gcgtctgtca tgatcatttc
     7081 aacaagtacg tatcctggga atgttttatg aacgatttct ttttctttcc catttttgac
     7141 ttcagtttct ttttcttcag gaacaacgac acggaaaata aagtcggcca ttttcatact
     7201 ttgcgcacga gattcgatat ttgcttttac tttgttttca tatcctgaat atgtatgcaa
     7261 gacataccag tttttttcaa aagattccat tgaaggctcc tcatttcatt gtaaaataaa
     7321 aaaacctcag tacacccgaa gtttttcttt cgcttcatta tagcactaaa agtacgttgt
     7381 ggctagcgag ttattttaaa atccagccaa ataagctttg gatggctgta tccattacgt
     7441 aaaacatcaa tccgaaaata atagaagttt cgatgactac taacgtatct ttacggagtt
     7501 gttttctgct tggccaagtt acttgtttga tttcatcttt tacgcttttt agaaatttca
     7561 tgagacaacc tcccttgcta ctgtttattt cgtttcttta tgtaatgtat attgattaca
     7621 atatttacaa aacttattga tttccaaacg ttcgccgctt tttccttcac tgactgattt
     7681 tgtgtagttg cgagacccac aaacggaaca agcgagtgct gcttttttct ttgccattta
     7741 cttctgcccc cttgctgaga atcagactta tacttcataa cagtatcacg taacttttta
     7801 cttgtcaatt tgtgaaataa actatctatt gttttggata aaattatgat atgattaatt
     7861 tgaaattaag ctaaaatgag acaattggag gtatagcgat gctattaaaa acacttgtat
     7921 ataagaaaaa agatctgaca accgttacag agactagtac attagaagaa gcattaaaaa
     7981 ttttagaaac ttccggatac cgttgtgtgc cgatcttaga ttcttcaggt aatattttcc
     8041 gtggaaacat ttacaaaatg catatctatc gtcataaagc aaatggcggt gatatgacgc
     8101 ttcctgtcac tcatcttttg aaaaacgcta caaagttcat ttacctggat acttctttct
     8161 tcaaagtatt ctttacgatc aaagagcttc cttatattgc tgtccttgac agtgaaaatc
     8221 atttttatgg tattttgaca catagtacgt tgcttaatat gctctctcaa tcttggagcg
     8281 tagaacaagg aagctatgta ctgacaattg cttccacagg aaagcaagga gatttggctg
     8341 ctattgcaaa aatcatttca aaacacagca gcattgccag ctgtattact cttgatatcg
     8401 aaaaagacga atacattcga cgtacattga tcacgctacc ggctaacact gaagcgaaag
     8461 tatgtgaaac gatcgtcaac cacttagaga aaaagaatta taaagtggta gaaattgaaa
     8521 atttgcaaaa ccaagaagca taatcaaaaa gcgaaaaaag aaaacagcta atctgctttc
     8581 ttttttcgct ttttataatt agacacgctt ttcaaaatca agcgcgcgat ctaaataata
     8641 catcaatggt gctgaaacag ccatgacgat aaactcactt aatgcaagcg tgccataggt
     8701 tgtccaaaat gcttggccac ctgttggaac taacatataa gcaatcagtc ccatgctgat
     8761 ggtaaagaag atcgtgttca atactaaacg catctttaca tttttcactt tgttttgcaa
     8821 taaagctgtc aggcctaaag aaagcaatgt ttggccgcca ccaaaaacca catccatgat
     8881 accaaaacca aagaaggcat tatagacgat gaccccgcct aaaactcccc aaagcaattt
     8941 acggttaaag acaactaaat gattcaaact ttctgaaata cgaaactgga tcggccctga
     9001 ggatacaggc gcaactaaaa tagttaacgc tagataaaga gccatgatga tgccatttac
     9061 aacgattacg gataaccgtt gtctgctttt cgttttttgc attttctctc ctcttttctc
     9121 ctagtttttt taacgcggga tggttgatga accgcggtta tgtgaaacaa acaataatta
     9181 taacagactt ttcatttatt tcaatccgtc ttatctgctt ttaaaaaagc aaaagcttaa
     9241 acaatgtaaa cgtttgctaa aaatcgtggg atatggtata aagtaagtgt aaggggtcat
     9301 aagaattccc agtaaagcag acgaagtagg atctgcaaga acagaattgt tgtgaaactt
     9361 aaataaataa aaaaggatgt gggaatttga gcaacctctt actagagaac ggtctagcaa
     9421 gcagctgaag atctaagtgg acatgccgaa ccttggaact tctccttacg taagtaatgg
     9481 atcatgcgct tgctaggctt ttttgtgttt ttcggtcttc ggaccttttt cattttccta
     9541 gacttctgct ataataacca agaattaatt ttgtaacaga tttttttgaa aaaacaagtt
     9601 tctttcattc aaaaaataga aaaagcttgc taattattgg ttaaccagca aacaggagta
     9661 ttaaaatatc ttgttttatt gaatagcagg aggaaatcat gaaattccat tatcatatat
     9721 tgatcaatcc atcggcaggc agcggaaatg gctataaagt agcagaaaga attttaccgg
     9781 tattaaaaaa taagcatatt gactatacac ttcattatag tgaatacaaa ggacacgatg
     9841 ctgagattgc tgaaactttg gcaaaagaaa cattgattcc ttggatagaa gaagaacaga
     9901 aaacaatcga tactttcccc cttttgatca tcgtaggagg tgacggcacc ttacatcagg
     9961 tacttgatac tttctatcag atggaagtag aattcccagt tgcttatatt ccagcaggtt
    10021 ctggaaatga ttttgctcga ggggcaggcc ttccaaaaaa tcccaaaaaa ggacttcagc
    10081 tgattttagc agctcaatca ccagaaaaag tccacataat ggcttatgaa gaaaaaataa
    10141 gtgaaaaaaa aggaatagct gttaataatt tcggtatagg attagatgca gctatcgtcc
    10201 atgcgacaaa tcattcttcc acaaaaaagc gattgaacaa atacaactta ggatcatttt
    10261 cgtatttatt ctctattctc cgtgctttat tcactcaaaa aggatttcca attctggtag
    10321 atgcaggagg aaaacaatta agtttttcaa acgcattttt atgtacagca acgaagcatc
    10381 ctttttttgg cggaggaatc gcgattgttc caactgctga tgcgtctaaa ccagtcattg
    10441 attttgtcgt ggtcgaacga atcaatttct ttaaaatctt gtggctcatt cttttactta
    10501 tacagaaaaa acaattgaaa tcgaaatatt tccatcacta cacaacaaac agattacgta
    10561 tcgtttcaac aacaccgcaa catggtcaag aagatggaga agaaatggaa aaacgacctt
    10621 ttgatatcac aataaccaca actaaacagt tgttttggtg ttaataaaag aggttttgtc
    10681 agaagctaca tctggaacac cgtttattcg gaaaaaagga ctgtgacacg acttttgtca
    10741 cagtcctttt tttactatgc agttaattct ttgcccaatt gggttgccat cgatagtttc
    10801 tttctttacc caaaataaat tggatcattg aaaacaccgc agcaaaagca actaagacac
    10861 aaccattgaa ccaaaaagat tctgcaaatg tttgattgta actgagtgtt tcactgatca
    10921 agttattatt ttgaacaaac caatatgttg gtgtgaatgc cgctattttg ctaaccattt
    10981 ctggcaagta ttctgctggt acaaacaccc caccgataaa gcaactgcct gtgataaaaa
    11041 tatctttgat cccaccgctg gtttctgagt tttttaccaa tgaagtgata caagccgaaa
    11101 agctaatgat cggcaataaa aacaagaaag tatttaaaat atgataccat accgttatat
    11161 cccacgaggt gtggatcact aacagaacca ttagaagtaa gaagccactg aacaacagca
    11221 gcgagtaact aatcaaacta aaggttactt tgcgattcaa gtttcgtttg gtaatgggcg
    11281 cactctggtt tcgtttactg atctctttgc gattaaacgc tagattgatg acgctgaaac
    11341 cgctaaaaat ggatagaaac aacccataag acaagaaatt aaaggttgtg cccgtcaaca
    11401 gctttttcat ccgctgacta tatcccgcac ttagctcaac ttctccagta accgagagtg
    11461 ccatttgtgt ctgttccata gctgcatcga ttgttttatc ttcttcttga aacagaatca
    11521 gtgtttgcaa aaaggtgttc acttgctgtg taacaactgt tttagaaaag gcatctgggc
    11581 gactctgtat cttgatcgtc gccatctttc ctacttcgac ttgttcggta aagtctgcag
    11641 gcagatgtaa gataatgttt acacgattaa aataaagagc atcatcgatt tctttttgtg
    11701 aggttccatc caatgtaacg actgtttcct tgtcattcaa atatttacga aggccatcga
    11761 ctacaggcga ctcttcttca ctaatcaagg cgattttcgc atcttgcaga gaggtatttt
    11821 caacatcaat attttgcgca aaaaagaatg tggcaacaac agtgataatt acacctatca
    11881 gtaaattcga tttatttgct ttaagcaatg tccaaatcgt tttataaagc gtcataacgc
    11941 acccctcttt ccatccaagc atttcctaac gcaaaaagga aaataaatcc gatcaaccat
    12001 agaagattgg tataaaaact agccaaatca gtgtagaaat aaagtttata caaactttcg
    12061 ctgatcaagt tgacgagatt taattgacca acaatcggaa tatgaagatc aatccaatac
    12121 ttcacttgtt ccgaccccat cataccagca aaaaagctca tcgcaatcgt cactgaaatc
    12181 aagatgctat ccttttgcac cagattcatt tttggtatca aattaccaac caatgtacct
    12241 aacaaaatcg cacacaacga ccccagagcg gtaacaatca tcaaccattg ccaacgttca
    12301 ccaaagtcta cttgatagat aaaacgaaag acagctaaca taatataaat ctctgtcaaa
    12361 acaatcgtaa agcttgctgc caaattagcg attgaaacta acgattgctt tctaggaatc
    12421 aaggacaagc gaataccatt tgacgattga tttgcttgct gatcctgtac attgcggacc
    12481 ccccacatcg tcccgtagag aatcgccatt ccaatcagag tgaagaaata aaaacttttg
    12541 aaactcatat tacgacctgc atgaacttct tgaaaagata cttcttgttc aaaaacagtc
    12601 atgatgggcg cgagatcaac gttctccact tctgccactt tactcgaaat tataccaata
    12661 cgctgtaaaa attgatccat gacgtttttc atcaacgtct gactcattcc tgcttgaccc
    12721 acatggagcg aaacagatga accatcaatg agataaaaac cagccaaatc atctgcattt
    12781 agcttttcat tcgcttctac ttccgatagt tcctgtactt caaataatgg tttatcattg
    12841 acttcgactt gttctaagac tgtggtaaaa ttttccgaaa gcgctgtttg atccgctttg
    12901 attacaattc cagtattaat cgtttcaaga ttgccacctt gatcaatctc gccaaaggcc
    12961 gccataaaca tcaatcctaa aagaattgga aaggccaatg tccaaaacaa catggattta
    13021 tttcgcagca gtatttttgt gcgatattta taaaaatgcc aaaacattat ttcccctcct
    13081 ctagtctctc aaatccttgc cagtaatctc taaaaagaca tcattcaagg acgcttcttt
    13141 ggttgctatt tttccgtaac tgatcttttc ttcttgtaag attgtaagaa tcggcaacaa
    13201 tactgtattt agttcagtag ttgttacttg gagctgacct tttttataag cgattccatc
    13261 agaagctatt gttcgctgaa tcgctgacaa cacattttct gggagtaatg ggatgtcgat
    13321 cgtcaaacga tccgccgtcc gtaccatatc ttttagagat tctttggttc ctttagcaat
    13381 cacctgtcct tgatccatga tcacgatctg gtcgcaaaga atttctactt cttccatgta
    13441 atgtgttgta tagacaatgg ttgctccttg tcgattcagc tccttgatac tttctaaaat
    13501 tttattccga ctttgggggt ctacagctac tgtcggctca tctaaaaaaa ttaaccgcgg
    13561 cttgtgggca atcccacatg cgatgttcaa ccgacgtttc aagccaccac taagttctcc
    13621 tggacgaaac gaaacatatt tttctaatcc cactaattga atcacctctt caatcaaggc
    13681 tttccttttc tctttttcgg aaacatataa accgcaaaaa taatcgatat tttcttgcac
    13741 acttagttcg tcaaagaccg caacgtcttg aggaacgacc ccaatcattg ccttgacagc
    13801 ataattttca ggagtcattg ttgtcccgaa caatttaatg gttcctttgt cataatttaa
    13861 caaagaaagc atacagttga tggcagtcga tttcccactg ccgtttggac ctaacagacc
    13921 taagacttct ccttcttgta cttgcagatc aaaatgattc aatgctacaa aatctccata
    13981 gcgtttgact aatttatcaa tttcgataat catcatgaaa aactccttcc aaatttcttg
    14041 ttgatctgac tataataaag tgcaagaaaa gaaactagtg acgattggct aaaccacaca
    14101 tgacatttgt cacaatgaag gagtctgcta tgcataaatc tcggctactc aacgaaacta
    14161 gctttctact ggttatctca ttgcttttgc tggtaagtca aggattcgtt gctatgcaag
    14221 ttatctattt attgatcgcc gttttattca ctggtgtcag ttatttactg cctacaaagc
    14281 caaattggat tttccaagtt attctatttc ttttatgtgc ctttttacct gatcttgtcc
    14341 tgtttctgcc agcgacgatg cgagtgatcg cccctgaaga aagccacctt gattacttgt
    14401 ttttgttagg ttttttgttg atttcgacgg ttggtaatca tccccccatc aaggtcgcct
    14461 ttgtcgtaat tttgctgttt ttttcctttt acttacgaaa aaaagatcaa cgaacgaccg
    14521 atcttgagaa aaagtacatt gtctccaaag atactcattg ggaaaaacaa caagagttat
    14581 cggaacaaaa taaagcattg gccctgtcac aagaaacaca attagccttg caaattgtgg
    14641 aagaacggaa ccgaattgcc cgagacatcc atgacaatgt cggtcatctg ctgtcaagtg
    14701 cgattttaca aattggtgcg cttgaaatga tcaatcaaga accaaaacta aaagaaccat
    14761 tagaaaattt aagtgccacc gttcacactg ggatggatcg gattcgtcaa agtgtccatg
    14821 acctccatga gacatcgatc tcttttcaac actccttaga gtttctgatc gctgattttc
    14881 cttcttctgt tacgattgaa ggaaacttgt ttgaaggatt gaatgaaacg cagcaaaact
    14941 gcttcttaat ggtcatcaaa gaagccttaa ccaacagtat caaacatagt catgccaaaa
    15001 ccgttgtttt acattttcga acgttgccgg ccttttatcg cttgcaaatc acgaatgatg
    15061 gcaccagccc acaaaaaaat tctgctcccg gtattggttt gaaaacgatg cgtcaacgtg
    15121 ttcaagaaca aaagggacaa gtccatattt tccaagaaaa ccagcaattt cagttaacga
    15181 tcattttacc aagggaggga caccaatgat aacagtagtc attattgatg atgatccatt
    15241 tgtgacgaaa tcgttacaaa ccattttaga aagcacgaaa gagatccgtg tgttaggcat
    15301 tggtcattgt gccaaggatg cgctagtctt atacgaaacc catcgtcccg atgttttgct
    15361 gacggacatc cgcatgccta aacaaacggg catcgatgct gccaaagaaa ttttggctaa
    15421 atttcccaaa gccatccttt tgcttttgac gacattcaaa gatgaagaat acatccgcga
    15481 agcattttcc atcggtgtca aagggtattt aatcaaacag aacttgcaag cgattattcc
    15541 ttctgtcaaa tccgcttata atggacaggc cgtatttggt aatgaaatca tcgagacttt
    15601 cactcaaatg atgaagaata aaccgacgat tgatagtcat gcttatgctt cttttagtga
    15661 acgtgagctt gcaatcatca aagaagtagc tgccgggaaa aacaataaag aaattgcaga
    15721 tgccttgtac ttgagtgacg gcactgttcg caattacatc agccaattac tagaaaagct
    15781 agatttacgg gatcgcacgc aattggctat ctatttttat cagcatttgc aataagtctt
    15841 atctaacaca aaaaaacctg aatgatgctc cttcgcatca ttcaggtttt tttcacatct
    15901 tctattcaat tgtcccgcaa accatttcct cacgattgaa agaatcaagg attcgcaggg
    15961 ctgccaggat tcgttggatt gttcggcgtg ttaggcggaa aaataggcgc cttgtctaac
    16021 gttttttcta gttttgattc ttcacgatcg tctcgttcta catcaggact ttcattcaat
    16081 ttgaattctt tttccatctc atctaacttt ttaaagtcat tgccagattc ttttgctaat
    16141 ttcgctaatt tatcttcggt ttctttagcc ataaagtaac gccccccttt tgatttcagc
    16201 ttagcatatc acactgaaaa aacaaaagaa aacgctaacc aacgatcatt tttagctatt
    16261 tctcatcttt aaaatcaagc attttttgcc ggtataaaat cgtagggaga actgttttcc
    16321 ataccaatca tcggatctac taactggtta tcgatcactt ctgctgtaag aacgaaatct
    16381 ttagaaacag caggttctac ctcttctttc ttttcttctc caacaaatga agaaaacaga
    16441 tctggttcca ctgtttccat tacttggttt ttcgtttcat tcgtcccact gtcatcttct
    16501 acaggtagct tttcttttac aacccgtggc tcttttgtat agttcccatc ttcaaatgga
    16561 tcatttccga ccaaagaatc ttcataagct gctagtttgg tccggagagt gatattcatt
    16621 ttatcattat ccatgatcct tgatttcaac gtagtcatcc ggcttgctga ttcattcgct
    16681 acacaagtga cataggcttg ctcttcccct aacaaaatca acagttcctt actgcgagtc
    16741 actgccgtgt agagcaaatt acgctgaagc atccgctgat attgatggac catgggcaaa
    16801 ataaccatct tgaattcact gccttgtgat ttatggattg agcaacaata agaaagagtg
    16861 attttattcc attcgtttct tttataagtg acctcatttg catcaaactg gataactaat
    16921 tcatccactt tatcttcaga atcttttgcc aagatgatac ccgtgatttc tcccatatct
    16981 ccattgaata cattcaattc gggagtattg actaattgga ggactttgtc tcctatccga
    17041 taaacggtgt cgttccaatg tacttccttt tttccaggtt tccctggatt gaatatctcc
    17101 tgcatcattt tatttaacgc atcgatccct gcaggtcccc gatacattgg tgctaatact
    17161 tggatatctt gtgcacggaa tcccttattt ttcgcttttt ccacaatttt agagatcaag
    17221 ggttcaattt gataagcatc acttcggaaa taggaacgat ctttttgatt ctttgtgaaa
    17281 tcttttggca gacgtccttc tttgatctca tgggcaagag gaataatact agaaccatca
    17341 ccttgccgat aaatctgatt gagttccatt ttgggaattt gttcgatttc caaaagatca
    17401 tggagtactt gaccaggacc gacagaggga agctgatctt tgtctcctac taagataact
    17461 tgcatattcg tcggaatcgc tttgaataat gtgttagcca gccatgtatc gaccatagac
    17521 atctcatcaa caatcaaaag tccgccttct aattctttcg tactgactga aggtgttttt
    17581 tcccgtccat tcagccccag aagacgatgg atcgtactgg caggcagacc tgtcgtttcg
    17641 ttcattcgtt tagctgctcg gccagttggt gctgcaagta gaataggaaa aatttcttgg
    17701 gtatattttg aaggatccaa ttccagtccg ttcaactctg caaaaagatt gacgattccg
    17761 ttgatcacag tagttttccc cgtacctggt cctcctgtta aaataaatag aggggaacgg
    17821 attgcttcag cgatagcttg ttcttgcgaa ggtccatact gtatgccgaa tattttttcg
    17881 atacgccgaa tattcttctg cacttctttt tcaggataat ggatttcttt tttacgactg
    17941 agaaggcgct ggatcgaatt accgatcccc cattcagaaa agtacaaact gttttcgtaa
    18001 agattagtct cttcttgttg tatctttcct tcttcaacaa gttggataat tacagtagca
    18061 acctgatcag gctggatttc aattgggcga cttgtttcta aaatacggat cgtttgctga
    18121 agcaatgtct ccgccggtac gtatgtatct cctgtttgaa ctgcatgctg aaaaatctga
    18181 tgcaagatag ctgctcgaat tcttctcggt gaatctgctg caataccgat ttgttcggct
    18241 agattatctg cacgtttgaa cccgattcct tctatgtctt cgactagctg gtacggattt
    18301 tcttcgatga tatccaaaga ctcgttctta taggcctggt agatactgaa agctaactga
    18361 ctaccgaacc cgtaacgatt cagtcccatg atcacttgat ccatcccgtg gtttagccga
    18421 atcgtctcag caagcatttc tctttttggc ttcgtcaaac cggagatttg ttttaatacc
    18481 gaaggatcag caatgatttt ttcgatagca tcttctccca gcaattctac aattttttct
    18541 gctgttttct tcccgattcc tgggaatttt tcgctggaaa gatacgctac gatcccattt
    18601 gcagttgttg gcttttcttg ctcatatctt tcgagtttaa gctgccttcc gtatttagga
    18661 tgatccacta attctccata aaaacgataa gtctcatttt cttgaatatc gccgaaactt
    18721 ccggtgacta caatctcttt ttcacggtaa tcagctgtgg tttcactgat gtgtaccaaa
    18781 agcactttgt aaaaattact aggattttga aaaaaaatcg cggcaactgt accaacgaaa
    18841 taaggcattt cttctggctg catcggaagc cgcctccttc ttctatagta aaggttctgg
    18901 tgctgtttca gttcctaaaa aatctgtttg gttccatact ttcagttcat atggcaataa
    18961 tctgcaaggc tcttcagtct ctaaaatcgt caaactacta ttgaacaatc cacccatttc
    19021 acgcaactca cttagctctt ttcctgtcat ccattgaatg gctgcagtta aagaagctcc
    19081 atgtcctacg aataaaagtg ggccatcttt atgtcgggca accgcatctg ctacaacagt
    19141 ttcgatacgt gtgattgccg attcaatcgt ttctccgtga aaaggagaag gatcatacag
    19201 atctaaatga ttacgcaaat tcggcagatt atccggatat ttctggtaca tttcatcgat
    19261 cgactgacct tctaaagtac ccagccctag ttctcttagc ttatctgtat aaaaaatctc
    19321 taccggacga gcaagctctt tgttgatacc ttctgctgta tcacgtgctc gctttgctgt
    19381 actggaataa attgctttaa aaggaacata ttttaccttt ttcccaaatg ctttgatttc
    19441 ttcgtaactt tgtggcaaaa gcggagaatc gccattgctc ccttgaaaac gtctttcctg
    19501 attccattgt gtcttcccat gtcgggtaaa atatagttcc atacgcagca aactcctgtc
    19561 tttcttttat tttactctat aataaactgt ctaatccagc ttgtcatttt catagtgatg
    19621 cgtcaattct aaattaggga atccttgctg gcgaagtgct tcatacacta tcattgcagc
    19681 tgtattcgat aaattcaatg agcggacatg ctcatcattc atagggatgc gtaaacactt
    19741 ttcttcgttt tcacgcataa atgtttctgg caaaccggtt gtttcttttc caaataaaaa
    19801 gaagtgctct tctccatcag caaaattttc gtcactatat actttatggg caaattttga
    19861 gatcaaatgt agtttacgat tacctaaaaa tgttaaaaaa gcttctaaat tactgtggta
    19921 agtaatattt acatcattcc aataatccaa ccctgcccgt tttagatgtt tgtcatcagt
    19981 tgaaaaacct agtggctcga ttaaatgaag cggagtattc gtggctgcac acgtacgggc
    20041 aatatttcca gtgtttgcag ggattaatgg ttcaaataaa acgatatgat tcatcaggat
    20101 cattcctctc atatttatgt tcgtttctat tttctgacaa tttgattttt gcataaaaaa
    20161 aaacgtatca actcggtgtc agtcactgcg agtcgttacg ttagtgaagc tcttctcact
    20221 aacttttatc agaacaggaa cctgataaaa accaatgaaa aaacaacttg ttgctaatat
    20281 aacaccctca actttttttt gcaacctcta ctcattaaaa actgctagaa aaacgttttc
    20341 tcttagttcc ttttaataat tctatgtcaa ttgtaatctt cttcaaagga ttcttatata
    20401 agtctgcttt gattcgctct tctacctgcc attctaaagg tgacatggcc aaaagatctt
    20461 tttgattttc ctctggtatc tcaaattcat aggttacacg ctgacgttca gttaatttca
    20521 ttgcttcagc aaacttggct actacacgtt cattggaata actctgtttt tcaggttgat
    20581 tcggataaaa agcctgacgt agttccttta aataattttc ttgtggcacc accttcaaca
    20641 cttctccatc ttctgagagt acacgttgga attcttggta atgagaaggc gaaaagatat
    20701 ttaaaaccgc gttgaatgtt tgatcagcaa acggcaaatt ggtcaaatca gctacacacc
    20761 aaaatgcttc ggcagattgt tctgtagctg cgtagactcc ttcttttgaa atatcaaatc
    20821 caacagcatt ttgaatcttt ttcaattttg aaagttcatt caagaagcta ccttctccgc
    20881 agccaacatc taatagcgag acttcttcag gtaaatgctg cgcaatagtc tcaataacgg
    20941 gctgatacat gccagattgg atcattctac gccttggaac gaacattcct tgatcgtatt
    21001 ctgttttaac cgcatgggat aaaaaataaa gtgttccttt tttggaaagg tcaaaacggt
    21061 gattattttt gcatatcaag ccattatcag acttttttac ttcttcttgg caaaccggac
    21121 agcggaacag ctgatgattt tctgccaaaa actggcgtcc tcggtcaatt ttttttaaca
    21181 tagttccccc tcatttctgt tttatcttac cgttagatgc tcactttggc aactgctaaa
    21241 aatatgatac aatgcctaga agaaagtgaa agataaagga gaagattaga tgatcaaaga
    21301 attttgcgct gaaaactaca catctattcc tctagcaatt gctagaggag ccgatcggat
    21361 cgaattgtgt gacaacttag cggtcggtgg cacaaccccg agtactggtg tgatcgaaga
    21421 aacgttaagt tatgctgggg aaaaagatat ccccgtaatg acgattattc gtcctagagg
    21481 gggcgacttc gtctataacg atatcgaatt gaaaatcatg catactgatt tgattgaagc
    21541 aaagaaatta gggacggatg gcgtagtatt tggttgtctt actccttcag gctggctaga
    21601 cgaagaggcc ttagaactat tgatcgaaac agcagaaggg ttgcagatca ccttccatat
    21661 ggcttttgac agtattcctg aagatcggca attcgaagca atcgattggc tggtagaaca
    21721 tggtgttgac cgtatcttga ctcatggcgg tcctgctgac aaaactattg tagaaaattt
    21781 cccacggctt aaagaattga ttgcctatac agatggccgc ttaatcattt tgcctggtgg
    21841 tggtgtcact gcagagaatg cagcacatgt agctaaagaa ttgaacgtaa gcgaagtaca
    21901 cggaaccaaa atcgtggatc ttcagttata atcttataaa caaaaaaaca tttgcaacag
    21961 gcataatgct tattgcaaat gtttttgttt ttttacataa aatagcccat aaataaagaa
    22021 gcaatattga aataaatcag tacactcgtc aaatcgctca aagtcgtgat aaagggaccg
    22081 cttgctactg ctggatcaaa tcctagacga tccattagca tcgggattaa actacctgca
    22141 agattcgcca ctgtgattgc aaatagcata gccatcccta tgacaaaccc caagataaaa
    22201 ttatgtttcc aaaaacctac gattagaaaa atcgtgatcc ccgtaacagc tcctgtgaca
    22261 acgccggtca agacttcagc caaaacaagt cgaacaaatc catgatcttt ctcatcagaa
    22321 atcgcaagtc gacgaacagc cacagctagc gactgggttc cagcattacc ggcagttcct
    22381 gtaatcagcg aaatgaagac tgctaaaata ctcgcttcac ttaccaagtc ttcatagtga
    22441 ctgattaaag aagcggtcga catacctaaa aacaacagag tgatcagcca aggcaaacgt
    22501 cgagacgctg cctttactgg attttcatta atttcttcca cattgacccc ggcaagtcct
    22561 gaataatcgc tagcagcttc atcatcaata acgtcgatga tatcatcgac tgtgacgatt
    22621 cctaacaaat gatcatcata atcggtaaca ggaagagcta agaagtcata atctctaaat
    22681 gtttgtgcca catcttcttg gtcgtcgcct acatgaactg aaagcactcg ttcgctcatc
    22741 agatcagaaa tcattgcgtc gtcatcattc acgattaggt cgcgcagaga aataacccct
    22801 actagctgac cttcttgatt aacgacatag atgtaataga ttgtttcagc tacatctgct
    22861 tcgttcttca gcacgtacat cgcagagcga acagtttgat tggctacgat cgaaacaaat
    22921 tcagttgtca tgatcgcgcc agccgtttca tcctcgtaat ggagaagttc cttgatttca
    22981 ctggcatcgt ctgccgacat caaacttaaa tatttagcaa tttgcttttt atccagcgta
    23041 ttaagcaagt caacagcatt atctgtatac atctcagaaa gcatatcagc tgcatagcta
    23101 ggacgcattt catctaggta ttctttcata tgttcgttgt cttcttcaat cacatcgaac
    23161 atatccgcta attctttagg cgacagatag gaatagatca gctgcctgtt ctcttctgta
    23221 agagattggt agaattgccc ctgctcatag atatgcatct ctaaaaaact gtttctgaat
    23281 gcctgaatat tattttccct taaatcttga gtcaactggg caaatctttc ctctaattct
    23341 tgattttcat ccaaaccaat ctcacctcgc cttattcttc aaaccgtctc acaactgcct
    23401 ccatgtctgc ggctaaaggc tgcttgaact ccagcaactc ttctgtaaat ggatggtaaa
    23461 aacgcagatc ataacaatga agggcttgtc tttttattcc cagatccatt cgcccgccat
    23521 acatatcatc accgagcagg gcacagccaa ttgcggaaaa atgaactctt atttgatgtg
    23581 tccttcctgt atgcagctgg atatcaacta acgcgatttc tgttagtcgc ttctctatcc
    23641 agtactcagt ctgtgccgaa cgtccttcat cagagaccat tcgcttcaat agcgaagaat
    23701 aatctcgggc gatcggcaaa tcgatatgtc catgtgccga taaatctgaa agccttccac
    23761 tgactaaggc ctgatatttt ttcacaaact tcttttcacg aagttgcata tctaattttg
    23821 cgtgcgcaaa tccatgcttt gcaaaaagca tcaagccaga tgtatcccga tctagtcgcg
    23881 tcaccacatg gattacttgg ttttcgtaac cttgtttttt ataataagcc tttacacgat
    23941 tagccattgt cccatttgga tggtattggg caggaataga cgaaacgcct gctggtttat
    24001 ttactaccag aacgtgttca tcttcataca cgatatcgat cggtgtttca tccaaaagta
    24061 cggtttcatg ttctccttca gcaggaatca caatggttac cttatcatcc ttagctagag
    24121 aaaacaagac attttctact tgatcattaa ctttgatttg accgccttga aattttattt
    24181 tcgctaacag accctttgag atcccttttt cttttaaaaa atattttact tgctgagaat
    24241 gatctttctc ataatcccat gtaaactgca tatcaatcct cactaataaa ggcatctttc
    24301 acacgatgcc aaaaatgcat atgtcgataa gaagcaaaat ggatccgttc ttctgctatt
    24361 cgataataaa ttgagcggat atttgctttt gcgacattca attgatcaac cgttacaaga
    24421 taatcttctg tattttccaa ttttatttct agccattcat catgggcaat cacgatcgga
    24481 gaacccaaag tacgaaacac tcgattattc agtgaagcaa tctctgccaa ctgaaaggca
    24541 ttgatactag gatggatcac agcaccgccg acacttttat tatatgctgt cgaaccagta
    24601 ggcgtagaaa tcgtcaatcc atctcctcta aaactttcaa acagctcgtt tttgatgtat
    24661 acatcggcta ccatcgtacg attggcccgt ttaatcgttg attcattcag tgctaaaaaa
    24721 tgctggtccg gtgtttcatc caaataactg atccgaacat ccagcaaggg ataactaaca
    24781 ctttgttccc ggttcgttcg taagctgtct actagttctt ccagctcgta atcccgccaa
    24841 tccgtgtaaa accctaaatg acctgtatgc acgcccaaga aacgcacatc attcagacaa
    24901 tgactgtagt gatggaacgc cgacaataat gtgccgtctc cgccgactga gatgaccaat
    24961 tctggctcat gatcatctcg ttgaatccct gcttgttcta aaagtgcgtt caaacgttct
    25021 gtcacttcta tagtctttgc ttctttatta tgaacgatcg ctactttcat cccctgcctc
    25081 ctctctttcg ctttctttct tcaaaagcgt tcgatagtag acatcatctg attttcctct
    25141 tccatgggag aataaccgct gtgcttcttg gatttcttca cggatactgg acatctcttc
    25201 atccaactga taggcagctt ctgccgcacg ctgaagtcgt tcactcattt cttctggaaa
    25261 aacgccttga tatttataat tcagcgaatg ctcaatcgtt gcccagaaat tcatcgcaag
    25321 agtccgaatc tggatttccg ccaaaatttt cttctcaccg ctgatcagct gtacaggata
    25381 ctcgatcacc agatgataag aacggtagcc acttgctttt ttatttgtga tgtaatctcg
    25441 ttcttggaga actttcatgt cttttctttt acggatgatc tcaacaactt gatggatatc
    25501 ttctacaaac tgacacatga tccttaaccc ggcaatatca gacatttctt cttctaaacg
    25561 tcccattgga atatgccgta attgtgattt tgttacaata ctatcgactg gcttgactct
    25621 cccagtgaca aattcaatcg ggacatgtcg attttgttca cggaactgtt tgcggatccc
    25681 ccgcagtttc actttcaatt ctgatacagt ttgttcatat ggtgctaaaa atgcttccca
    25741 atctcgttcc atagctgata cctctacttc attaacattc attgtttatt ctaccatata
    25801 tgcaaagttt tttcgtactc ttgatttatg cattgaccaa aaaaagaaaa ttaggcaaaa
    25861 tagacaaaaa ggagtcgatc aaatgacaca aatgcttgaa atcgaatata aatctatgct
    25921 gacaaagcaa gagtacgaga tattcatcgc tcactatcaa ttaacagata aagatttccg
    25981 tgtacagact aatatttatt tcgataccgt tgatgaacag ctgaagaaac aaaattgtgg
    26041 cctacggatc cgtttcgttg gtcatcaagc tgaatataca ttaaaaacac ctgctgaaaa
    26101 agggcgtctc gaaacaacgg atacctttat aacagaagaa gcagaagcat ttatcttcga
    26161 aaaacgtctg cctcgttcag gcgcagtttt tcaaaaactt tctgatttga atatcgatcc
    26221 tgcttcatta atccaaaccg gaaagcttac aacaaaacga gctgaattcc ctattgaaga
    26281 aggactttta gctattgatg aaagctgggg agacaatcta cacgattttg aactggaact
    26341 agaggtacgg gatgcatctg tgggaaaaat tgcttttata aattttttaa aacgtttttc
    26401 tttaccttat cgtcctgcta agaacaagat ccaacgtatg cttgaagcta aaaattagaa
    26461 acctttcatt ttcacaaggc acttgagttc atttttttac ttttttctgt taagttatag
    26521 gatgtgaaag aatctagtca ctagttgtat agaatctatt ttgggggaga ttcatatgat
    26581 cgaaatctat ttatttgtta atcctttagg ggaatactgt ttcgaaatgg aacaacagtt
    26641 attacaattt atcgaagaag agtacgggac accatcaaaa gaaaagatgc aatttcgctt
    26701 tcttcctttg gtcaatttgc agacaattgg ggatgtcatg caacaaaaag gaatttctca
    26761 gaacaatctt gaggaacgta atcacttatt ctcaatgact tattctgcag cattggactg
    26821 caaagcggcg cagtttcaag gaaagaaaaa aggccgccgt tttttgatca aattgcaaga
    26881 agcagtcggc tgtaatgaca taccatattc tcaagaactt gctgaatcca tatttgaaga
    26941 aatcggcggc gatttgaata tgtttaaaga agatcgtcag tctgacttcg ttaaagaagt
    27001 attcttttct gatcaaaaaa ttgctcggga aatgggcatc acaaaacacc cttctgcagt
    27061 cgtttacaat tatgcctgcg accgtgattt tggtgtttta gtagaagtaa aaggtacaag
    27121 tagcctttgg agaatcacag agctgtgtaa aacaacagat aactcatatc aagtttttaa
    27181 tggtgaacat ttacatacaa atgattctca gttccattca agaactagcc atttacactt
    27241 gctttctaat taaaaaaggc tctttgtcaa atgatgttgg taaagagaaa tcttagaata
//
LOCUS       DAFBVQ010000033        26956 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.033, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000033 DAFBVQ010000000
VERSION     DAFBVQ010000033.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.033"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            122..1126
                     /locus_tag="LLC22_001616"
     CDS             122..1126
                     /locus_tag="LLC22_001616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434898.1"
                     /translation="MSDNQLLEVQNLHTGFRLKDDYYDAVDDVSFTLDKNEILAIVGE
                     SGCGKSTLATTIMGLLDPNNTKITGEILYNDLNLIDLNETLYNKIRGNDIGMIFQDPL
                     SALNPLMRIEDQIKEGLSYHTKMNAEQRQARALELLEQVGIPNPARVGRQYPHELSGG
                     MRQRVIIAIAIACKPPIVIADEPTTALDVTIQAQILDLLKDLQEETKTGIILITHDLG
                     VVAEMADRVAVMYGGQFVEVAGVKELFDHPKHPYTRSLLNSIPQEGNHDAELHVIEGV
                     VPSLKNMPRKGCRFAPRIPWIPASDHEEEPILHEVAPNHLVRCSCYKHFHFRDEKGEV
                     "
     gene            1127..2071
                     /locus_tag="LLC22_001617"
     CDS             1127..2071
                     /locus_tag="LLC22_001617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434899.1"
                     /translation="MTELITIKDLKVHYPIRSGFFNRVTDHVYAVDGVDFIIEKGKTY
                     GLVGESGSGKSTTGKAVVGLEKVTAGQIMYEGKDVTKRSNRKKMGYNKDVQMIFQDSM
                     SSLNPKKRVLDIIAEPIRNFERLSDQEEKKKVKGLLDIVGMPEDALYKYPHEFSGGQR
                     QRLGVARAVATNPKLIVADEPVSALDLSVQAQVLNFMKRIQQEYGLSYLFISHDLGVV
                     KHMCDNIAIMYKGRFVEIGTREDIYNDPRHIYTKRLLSAIPQIDVENRESHKENRRRV
                     EQEYIQNQKEYYDATGRVYDLRTITTTHKVALKDGGAS"
     gene            2071..3033
                     /locus_tag="LLC22_001618"
     CDS             2071..3033
                     /locus_tag="LLC22_001618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434900.1"
                     /translation="MWKTILRRVLLMIPQVIILSVLIFLLAQAMPGDPFTGLINPNQD
                     PAVIEQMRQAAGLNDPWYVQYFRWIGNALQGDFGQSFLYKRSVADLIGERIINTLYLS
                     ILTVVLTYLIAVPLGMLAGRYQNSILDKIVVIYNFFSFAVPLFIFGLIMLFVFGYRLG
                     WFPTSGSQTLGLQGGFITQWIDRLKYILLPSITQAFLATAVTIQYLRSEVIDSKSLDF
                     VRTARSKGVPTNKVFSRHIFRNAALPMASQMGYEITSLIAGSVVIEKIFGYPGVGKLF
                     IDSIGQRDYTVITSLVLILGIATLVGTLLSDIIMSIVDPRIRIQ"
     gene            3060..3974
                     /locus_tag="LLC22_001619"
     CDS             3060..3974
                     /locus_tag="LLC22_001619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434901.1"
                     /translation="MSEKNNTAVQESIPPMGIRMIAREFKKDKIAIFSLGLLVVLLLV
                     IFIGAMLTDQDKVMYVSIFDKYAAPGTVSTQGQKFILGADEGGRDVLGQLIIGARNSV
                     TIGFAITILTSIIGVGLGIISGYYGGIIDNILMRIVDFIMILPIMLIIIVFVSIISRY
                     NVWSFIFIMSAFYWVAKARLFRSKTLSEARRDYVSASKTMGTNDFKIMFREIMPNLSS
                     LIITNLTMNFAANIGIETTLTFLGFGLPANVPSLGTLIGYASNGEVLVNRQWIWLPAS
                     ILILVLMLSINYVGQAFKRSADARQRLG"
     gene            4000..5781
                     /locus_tag="LLC22_001620"
     CDS             4000..5781
                     /locus_tag="LLC22_001620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligopeptide ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5434902.1"
                     /translation="MKKTIFGFAALMSAVVLAACGGGGTDTSGNNSGGNGNNKEELTF
                     PIATKNNDDAIEDGELEAAVATDSQFKGLFQWEFYQDSYDAAFMAPSHEPLFANDDDF
                     RITDDGAATLDLDEDTKKATIKVKDNVKWSDGEDVTADDVIFPYEIIGNKDYTGIRYD
                     DTFRNIVGMEEYHDGSADTISGIKKIDDKTVEIEYKEVNPSMLQSGGGIWSYAAPKHT
                     LEGVAIKDMESSDQVRKNPVTFGPYYMSNIVAGESVEYLPNEHYWNGTPKLKKITMKS
                     VPMASATEALNSKLYDMIFQMPTDTYDTYKEIAGYTNLGREQTSYTYLGFKLGKWNAD
                     TKSVEYNPDSKMADKSLRQAMGYALDNNAVGERFYAGLRSNATSLIPPVFQSYHDDEM
                     KGFTQDLDKAKKLLDDAGYKDVDDDGLREDKDGNKLTINFASMSGGETAQPLADYYIQ
                     QWKEIGLDVQYTTGRLIEFNSFYDKLENDDPEIDVYQAAWNTGTDPNPSGLWGPNAAF
                     NYTRYESEENTKLINDISSSKAFDEEYQKEAYQKWQQYAFEEAFAIPTLFRNEVLPVN
                     DRVKDWDWSYDVPNPWANVSVTADSRS"
     gene            6129..6815
                     /locus_tag="LLC22_001621"
     CDS             6129..6815
                     /locus_tag="LLC22_001621"
                     /EC_number="3.1.26.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177197.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease III"
                     /protein_id="HBK5434903.1"
                     /translation="MDNQLTKELKENYNIVFHDLNLLEQAFTHSSYVNEHRNLQLSDN
                     ERLEFLGDAVLELMVSQYLFRLYPHLPEGKLTKTRAAIVREDSLSKFAKDCHFDQYVL
                     LGKGEENSGGRTRPALLCDLFEAFLGALYLDQGFDTTHAFIEKVIFPKVKAGAFSHEM
                     DHKTKLQEVLQKSGDVSIEYRLINEEGPAHERVFWIEVYVDDQLIGTGQGKSKKLAEQ
                     AAAENALAAL"
     gene            6835..10416
                     /gene="smc"
                     /locus_tag="LLC22_001622"
     CDS             6835..10416
                     /gene="smc"
                     /locus_tag="LLC22_001622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287897.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chromosome segregation protein SMC"
                     /protein_id="HBK5434904.1"
                     /translation="MYLKRIEIAGFKSFADKTVIDFENSVTAVVGPNGSGKSNITEAI
                     RWVLGEQSAKSLRGGKMPDIIFAGSDTRKQLNIAEVTVILDNSDHYLPLEYNEISVTR
                     RYRRTGESEFFINKQSCRLKDIQELFLDSGLGKESFSIISQGKVEAIFSSKPEDRRGI
                     FEEAAGVLKYKQRKKKAEQKLFETEDNLSRVQDIIHELEEQLTPLAAQSEAAKEFLRL
                     KETLTQTDVSLMVAEIKTAKKDWDNKQAQLAKFNLELGKLSESIQEQESILAKQRKEN
                     AQADRLIEKNQQVLLDLSEKLKQTEGQKDVLQERTKHTQKSSQEYQTSLAEAQKKVKH
                     FEKLQESLMKAAAEKETEIQKAEANLIKTQQELEKYQKSTKELLAELRDQYVDLMQEQ
                     AAVGNELKYLERQYIQETAKSKQTLAKQSEVEASVDRLILQKEELTQKQAQLKSSLTE
                     TKEKLEMIQQNGKKFQEALAKEQPKMYQLMNQVQQLRARKKSLQEIQENYFGFYQGVR
                     LVLQHKQQLSGIVGAVAELIDVPADFTLAIETALGGAAQHVIVENEKDARQAITYLKQ
                     QRGGRATFLPLTTIKPRQLPAHILTQAAAVEGFIGIASEQVSYPDQIQTVVQNLLGTI
                     LLAKDLTSANAIAQTIRYQYRVVSLEGDVMNAGGSMTGGANKRGNQGSLFVQNQELKQ
                     LTSEFEEADKQLQAQEKKVQELQQETARLAEEQEVLRTRGEQLRFEEQEATNQLQNII
                     NELERFEKEKQISTFETRELQQFIEDYEKQTNELKDKQTDLESQRQKIDEEIKSLSQE
                     SDQMEARRAQVQSQKAQEQADLAVLKEQFNHLQIQLRGARVQKAEATERQEAIEKQLA
                     TLTADFSDHEVTEESLEKQINELSAQRETLKAELAKAKEQRDRRQKEIDKLEAVLAER
                     NREQKARLSEQSKLEVQKDRAEMILDNHLTYLQSEYQLTFEKASQDYQETTDIEDSRT
                     KVSSLKEQIEKLGPVNLNSIEQYEQVSERHTFLATQRDDLLAAKNQLFETMDEMDDEV
                     RTRFKEVFEAIRQEFKIVFPNMFGGGKAELVLTEPTDLLKTGIEIEVQPPGKKLQSLS
                     LLSGGERALTAIALLFSIIRVCPVPFCILDEVEAALDEANVKRFGRYLSDFQDDTQFI
                     VVTHRKGTMVAADVLYGVTMQESGVSKIVSVRMEDINEEAKINETKV"
     gene            10425..11234
                     /locus_tag="LLC22_001623"
     CDS             10425..11234
                     /locus_tag="LLC22_001623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5434905.1"
                     /translation="MIKLVAIDLDGTLLNEQKLISDENKQALAQAKQQGVKIVLCTGR
                     PLAAMAHYLQELGLVDEGDYSITFNGGLVQKNDTGEIMEKKVMEVSDIQRLYKLAQQL
                     DLPLDVLSDNVVLQLPSAPRKQSLYNVLNKLLQFQPADISDITDEFVLNKAVIAYDQE
                     ELDPKIKEIPAEFHEMYEIIKTRSMLLEFMPKGVTKAYGISLLAKDLGLKQEEIMAIG
                     DEENDLPMIQYAGLGVAMENAVPFVKEAADFVTASNEENGVAKVIQKFVLE"
     gene            11245..12243
                     /gene="ftsY"
                     /locus_tag="LLC22_001624"
     CDS             11245..12243
                     /gene="ftsY"
                     /locus_tag="LLC22_001624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348059.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal recognition particle-docking protein
                     FtsY"
                     /protein_id="HBK5434906.1"
                     /translation="MGFFDKIKRAFTGEEKTEEVEVQEKYDKGLEKTRKTFGERMNEL
                     FANFRTVDEDFFEELEETLIGADVGFETAIRITEALRQEVKLRNAKKSAEVQNAIIEK
                     LVDLYEAEGINEVNELNIQEDGLTVILFVGVNGVGKTTSIGKLAHQFKNEGKKVLMAA
                     ADTFRAGAIDQLVVWGERAGVEVVRGNAGGDPAAVVFDALERAKTEQADVLLVDTAGR
                     LQNKVNLMNELEKIKRVIQRELPEAPQETLLVLDATTGQNAMVQAKQFKETTDVTGLV
                     LTKLDGTAKGGIVLAIRNELHLPVKLVGLGEGIDDLEPFDPNDFVVGLFKGLLKEE"
     gene            12430..14697
                     /gene="gshAB"
                     /locus_tag="LLC22_001625"
     CDS             12430..14697
                     /gene="gshAB"
                     /locus_tag="LLC22_001625"
                     /EC_number="6.3.2.2"
                     /EC_number="6.3.2.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325181.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional glutamate--cysteine ligase
                     GshA/glutathione synthetase GshB"
                     /protein_id="HBK5434907.1"
                     /translation="MMNFKQLLLHVNARPFIDQARFGIEREGQRVDLAGNLAKTDHPA
                     IFGDRSYHPYIQTDFSETQTEMITPVTDSIPELFQYLAAVYDVTARSIPKEEMIWPLS
                     MPPALPEKDEEIIIAKLKNFEDVLYRRYLAKEYGKRKQMVSGIHFNFEFGDELLRTLF
                     SHQEEFQDFSEFKTELYLKTARNFMRYRWMITYLFGASPMSEKNYFLDESHPQEPVRS
                     IRNSALGYTNHPNVKVSYASMKQYLADIERMIEEGKLSEEKEFYTPLRFRGGKKVADL
                     ATTGVRYIELRNIDLNPYARLGINPEQVRFLQLFLMYMLWTEEKEDCDQWVAEGTTRN
                     NKVALEQPSDQTEFHQEGREILEGMKQMLVELDWLDSLYLVEEALTQMDHPEQTLAAK
                     LYQEAQLSSQQEVAVALGHQYYKESHERPYQLAGFREMELSTQIFMFDAIQKGVQVKV
                     LDESDQFLRLQFQDHVEYVKNANMTSKDSYIVPLIMENKTVTKKVLKEAGFRVPGGAE
                     FSSMEEAVKAYPRFAEQAFVIKPKSTNYGLGITIFKEGASLEDYQAGLAIAFREDSSV
                     LVEEFMPGTEYRFFVIDGEVQAIMLRVPANVIGDSIRTVKELVEEKNSDPLRGTNHRA
                     PLELIQLGELEQLMLKEQGLTIESVPQANQIVYLRENSNISTGGDSIDMTDEFSEAYK
                     KIAVSAVEALGAKISGIDLIIPDKEIDPTTDKKAYGIIEANFNPAMHMHVYPFAGKGR
                     RLTMNVLKLLYPEVF"
     gene            complement(14786..15238)
                     /locus_tag="LLC22_001626"
     CDS             complement(14786..15238)
                     /locus_tag="LLC22_001626"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309824.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YueI family protein"
                     /protein_id="HBK5434908.1"
                     /translation="MAQDDVKSHLDKGLYGTPLVNPEEQHKYLGTFRERCYLSMTVAE
                     MIQPKNKENFLKELKKHPDASILLNGALPLSVQNQYIQLATKSNSRFTVVNDYVTANP
                     EEFGLLLTAKEAVNEPVIDIEKKYPEENSSPAEKEKPKKKKSFWDRLF"
     gene            15388..16338
                     /locus_tag="LLC22_001627"
     CDS             15388..16338
                     /locus_tag="LLC22_001627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBK5434909.1"
                     /translation="MRYGRLVALLVILSSISLFIGVSNVQLSELLQLDGQSLQILLVT
                     RLPRTICLILVGATSSICGLIMQHLTQNKFVSPTTAGTMDSARLGILVAMIFLPGASL
                     IVRSLTAFCFAFAGTLLFLSLTRLFLQKNQLMLPLIGVMLGNIIGSVATFFAYQFQLV
                     QNMTSWLQGNFATVIRGNYELLYAVVPLLLLVWLFAYRFTIIGLGESFAVNLGIDYQK
                     MQFLGIGLVSLASAVMLIMVGSIPFIGVIIPNLVSRIYGDQVHKTIGVTALAGSLFLV
                     FCDLVARVLIFPYEIPVSVIVGIIGGAIFLYLLIRGRRYA"
     gene            16331..17290
                     /locus_tag="LLC22_001628"
     CDS             16331..17290
                     /locus_tag="LLC22_001628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron chelate uptake ABC transporter family
                     permease subunit"
                     /protein_id="HBK5434910.1"
                     /translation="MLKKKPSIFIGMLVLVLFVTGMYLTIHTYGNWHFACALRSKKIF
                     AFILVSLAVSSATISFQTITHNQFLTPSVLGLESLYVLVQTVLFFFIGGVTMLQQTGT
                     VFFLLNVGLMVGLSLLLFFFLLKKMRANLFLLLMSGMILGTLFGSVSTFLQVIMDPNE
                     YDLLQGRLFASFGNIQSQYLLPASLIIIGCWYLLFRYRHVLDVFHLGNEQAVNLGIDT
                     DRFEFLILCCVSLLTGTSTALVGPVTFLGFIVANISYRVFSTYRHGQLFIGSFLVAML
                     FLTGGQLAVEQIFGWNTTVSVVVEFVGGIYFVTKLIRERKSIL"
     gene            17287..18042
                     /locus_tag="LLC22_001629"
     CDS             17287..18042
                     /locus_tag="LLC22_001629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5434911.1"
                     /translation="MIDLQKVNKLYHGKSVVKDVQLTIPEKKLTAFIGPNGAGKSTVL
                     SMISRLIPKDTGEIYLDHNEVKAWKSNELAKKLSILRQSNEINVQITVKELVEFGRFP
                     YTKGKLTTKDEEIVQESLEHLGLEEIADQSIDTLSGGQLQRAYIAMVLAQDTDYILLD
                     EPLNNLDMNFAVQIMQILKNLVQEIGKTIVIVLHDINFAASYADEIVAMKDGQLFTQG
                     TTQEMIKKDVLDELYEMDIRICEIEGRRFCLYF"
     gene            18065..19018
                     /locus_tag="LLC22_001630"
     CDS             18065..19018
                     /locus_tag="LLC22_001630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287908.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="siderophore ABC transporter substrate-binding
                     protein"
                     /protein_id="HBK5434912.1"
                     /translation="MKKLVVGILILASFGLAACGNSNNTSQADTKKSSTQTETTLTIT
                     DSNGDQIEVPNNPEKVVVFDNGSLDTMDALGVGDKVVGAATSSLPEYLSSYKKVESAG
                     GIKEPDLEKINQLQPDLIIISGRQRDFQKDLSQIAPTIFLSLDAKNPWESFQQNVTAL
                     GEIFGKQEEAKTQLEELSSAIDQTKKKAEATDKKALVTLVNEGQLSAYGSGSRFGFIH
                     DLFGFEQADDQIEASTHGQSVSYEYVLEKNPDILFVVDRTKAIGGDDSKDDISANELV
                     AQTNAGKNQQIISLEPDVWYLSGGGLESMKLMIEDVNQAFK"
     gene            complement(19662..19958)
                     /locus_tag="LLC22_001631"
     CDS             complement(19662..19958)
                     /locus_tag="LLC22_001631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phenylalanyl-tRNA synthetase subunit alpha"
                     /protein_id="HBK5434913.1"
                     /translation="MKEYIKNIYFIEETQNIEGSYIEVKTLFVNEDKTKALDIYKKLA
                     SKKTNSFGLILSEYKIKAEESYFYQLLKRWSKLPADFYRKMQIINYQPLAETHA"
     gene            20313..20669
                     /locus_tag="LLC22_001632"
     CDS             20313..20669
                     /locus_tag="LLC22_001632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBK5434914.1"
                     /translation="MKLEVTKEAQEVLKNKLEADDQLLLDIENGDGPFAESQVSCQLD
                     TAFRLIIVKKDTQTDLSLYSVVADTPVGPIKIKDSAILYMDDPSTLALEPTYNSLQLK
                     GPSGLRKGNLQVVRKD"
     gene            20679..21578
                     /locus_tag="LLC22_001633"
     CDS             20679..21578
                     /locus_tag="LLC22_001633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphohydrolase"
                     /protein_id="HBK5434915.1"
                     /translation="MGKLAIISDLHVDINKFGESELMQLWQVLQKHKITRLHLAGDTA
                     NKVDRCLAVVEFFVNKGLSTTFHFGNHELADVPNEQMMDHFPDPHFLNERYIALNEQT
                     VLLGMNGWYDYQFSELKDYEAIVRMKRLYWYDRFIQRGKTDLEVNAEMLAAAKNLLDQ
                     LEAKKLEVILSTHFVPKRAFIMYQSAPYERWNKLNAFLGSESFGELLDRYSNIKQVVF
                     GHTHRRFEDKSIGHTIYSCRPFGYYYEWQLTRDFVLKEQLLDSYDPMKLRVLLRAHHP
                     AFQAYQTQHLQEEFEQAMTIVPY"
     gene            22095..22826
                     /locus_tag="LLC22_001634"
     CDS             22095..22826
                     /locus_tag="LLC22_001634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322951.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBK5434916.1"
                     /translation="MMKKEIVLTAAMMLFSMVASTTFVSATEVYPKEYNTEGTITFEA
                     GDEGVTPPVDPENPDPNKPVDPSDPPSPGTGGALSIDYGSKFKFGTQKISTADKTYYA
                     AADVMNDGSRKPTYVQVTDRRSTLSGWKLSVSQPEQFKTASGDELVGAQLKFTKGQAV
                     SLVDPTYTPQTVNSELTLTPGGNNTLAINAKSGTGVGTWVYRFGANENENQDAVQLSV
                     PGKSVKLAQQYSTKLVWTLEDTPNN"
     gene            22971..24998
                     /locus_tag="LLC22_001635"
     CDS             22971..24998
                     /locus_tag="LLC22_001635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBK5434917.1"
                     /translation="MKKRRIVLILSSLLVTNIFPIIGYSLELNQLEHGNRRDEESKLT
                     STFDSLIESNQTQESSEDLSISSSGETTDNVEAEGSDKQGLEDAPISAVELPDDPNII
                     SIDKIFQTPIGTSTSILENGKLLQLNPAERSQRGAIWSNKKISLLSDFTFKSYLYLGN
                     QRDRAGDGMTFTLTGDPRMASNPSQVIGSPGMGIGSYSTRSGQPYIANALSIEFDTYK
                     NSGSSDRMDREITADNRGHGHVAFVTPKPNNNNYSGEHTGVTVAPTFLSNGTWRLLII
                     KWDAEQRSLTYDLEGVGRSSRIIPDLIRQFGSTEVNWGFTSSTGTFFQENAVAVTRLP
                     SNVTSTADVKVNDSDYGAIAEAGGNDKITIRNTLKVEGDFLEYKKMQTSIDLPQELTI
                     PEHILINGNQIDAKDILITGNRVTLNLTDYFIAGDTLIIELETTLQEVIPEKVLTMHF
                     EYLENGNLIEQSNEINLKIAKLKEIDIHVYYKDKDSQIDIAEMKTITGKIGEKYKETP
                     IDIEGYVFDSDSANTEGIFSENTEDIYFYYRKGKLYLSTAPQYVNFGKHKISSRPLSE
                     FGQFSGGLKIIDERAFGSWKLQLKQEKVLTNGDFELPEALSFVTSENTTVIGTSAVTI
                     FESDQKGESDLSSLLDSTAHRGIRIDIPVENQRIGTFEGKLSWILADVPGN"
     gene            25106..26203
                     /locus_tag="LLC22_001636"
     CDS             25106..26203
                     /locus_tag="LLC22_001636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307341.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 and DUF3324 domain-containing protein"
                     /protein_id="HBK5434918.1"
                     /translation="MIKGAIFLRPKQQLFITLLVILGALFNNISVSASAFNFSVTPIT
                     SENQIDKRKTYFDLQLDPDQEVEVKAELRNDTEKEVKIDISVNSATTNSNVMVEYGKN
                     EIEKDMSLIFDLVDYVSYPQIVTLKPKSVQTVAFHVRMPNERFDGVLAGGITFQEIQT
                     EKDQTETKDQSLSIENEYTYIIALLMQQTLNEVAPNLTLHEVKPDQINARNVILANVQ
                     NDQKTYINQVVIETKITKKGHSEVLYQEEKEGLQIAPNTNFSFPTALNGQPLTPGEYH
                     LTMTVLGNENENGKFSRKKGNTTINYTNQWVFEKDFTIDGKVAKELNTTDVTIKKDNN
                     WIYILVASLFLLFILLCILLFVLRKKEEKEK"
     gene            26510..>26956
                     /locus_tag="LLC22_001637"
     CDS             26510..>26956
                     /locus_tag="LLC22_001637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316575.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434919.1"
                     /translation="MNYEFFLSKEDHRSYSLLKYLEASSNLSESISNVQEELSLSTFL
                     LKKTIDKLKHDLQKFDLEKNLRVTVSELDICLEINGKCSSKALLSRYITDSLSMKMVL
                     AFFQEKYISVENFAKQHHVSYSVAYKVLQRLKRNLKKYQIFFEKRKL"
BASE COUNT         9041 a         4666 c         5688 g         7561 t
ORIGIN      
        1 aattattaat aattcattac acaaagataa gaataacctt tgttataaaa cgatttattc
       61 tgtgtaatgt ccttttttat taagaaaaac ttccatttag gaagcagaga ggggtattcg
      121 attgtccgat aaccaattat tagaagttca gaacctacat acaggattcc gactcaaaga
      181 tgactattac gatgcagtag atgacgtttc atttacttta gacaaaaacg agattttagc
      241 aatcgttggg gaatctgggt gcgggaaaag taccttggct actacgatta tgggattact
      301 tgatcctaat aacacaaaaa ttacaggtga gattttatat aacgatctga atttaatcga
      361 cctgaacgaa acgctctata ataaaatccg cggaaatgat atcggaatga ttttccaaga
      421 tccgttgtct gcattaaatc ctctcatgag aatcgaagac cagatcaaag aaggactttc
      481 ctatcacaca aagatgaatg cagaacagcg tcaagctcgt gcactagaat tgctagaaca
      541 agtagggatt cctaatcctg cgagagttgg acgccaatat ccccatgaac tatcaggcgg
      601 tatgagacaa cgtgtcatca tcgcaatcgc aatcgcctgc aaacctccaa tcgtcattgc
      661 agatgaaccg acgacagccc tagatgtaac catccaagca cagattcttg atttactgaa
      721 agaccttcag gaagaaacaa aaacagggat catcttgatc actcatgact taggagtcgt
      781 agcagaaatg gctgatcgag tggcagtgat gtatggcgga cagttcgttg aagtagcagg
      841 tgtaaaagaa ctgtttgatc atcctaagca tccttataca cgctctttac tgaactctat
      901 accacaagaa ggaaatcatg atgcagaact ccatgtgatc gaaggtgtcg ttccttctct
      961 gaaaaacatg cctcgtaaag gttgtcggtt tgcaccacgt attccatgga taccagcaag
     1021 cgatcatgaa gaagagccta tccttcatga agtcgcaccg aaccacttgg tacgttgctc
     1081 ctgctataag catttccact ttagagacga aaaaggagag gtgtagatga cagaattaat
     1141 cacaatcaaa gacctgaaag ttcattaccc tattcgcagt ggattcttca atcgagtaac
     1201 ggatcatgta tatgctgtag atggtgtgga ttttattatc gaaaaaggaa agacatatgg
     1261 tttagtggga gagtctggct ctggaaaatc tactacggga aaagccgttg tgggattaga
     1321 aaaggtaaca gccggacaaa tcatgtatga aggaaaagat gtaacgaagc gaagcaaccg
     1381 caaaaaaatg ggttataaca aggatgtgca gatgatcttc caagattcaa tgtccagttt
     1441 gaatcctaaa aagcgagtgt tggatatcat tgctgaaccc atccgaaatt ttgaacggtt
     1501 aagcgatcaa gaagaaaaga aaaaggtaaa aggactgcta gatatcgttg ggatgccgga
     1561 agatgcgcta tataaatatc ctcatgaatt ttcaggcgga caacgtcaac gtctaggagt
     1621 agcccgtgct gttgctacca atccaaaact gatcgtagcc gatgaacctg tatctgctct
     1681 ggatctatct gttcaagcgc aagtattgaa tttcatgaaa cgaatccagc aagaatacgg
     1741 cctcagctat ttattcattt cacatgattt aggtgtagta aaacacatgt gcgacaatat
     1801 cgcaattatg tacaaaggtc gatttgtaga aatcggtaca agagaagaca tttataatga
     1861 cccgcgacat atctatacga aacgtctgct ttcagctatt ccgcaaatcg atgtagaaaa
     1921 tagggaaagc cacaaagaaa atcgacgaag agtagaacaa gagtatatcc aaaaccaaaa
     1981 agaatactat gatgcgactg gtcgagtcta cgatttgcgt acgatcacaa ctacacacaa
     2041 agtggcgttg aaagatggag gtgcaagcta atgtggaaaa cgattctgcg acgtgtttta
     2101 ttgatgatcc cgcaagttat tattttaagt gttctgatct tcttattagc ccaagcgatg
     2161 ccgggggatc catttaccgg tttgatcaat ccaaatcagg atccggcagt gatcgaacag
     2221 atgcgacaag cagctggctt gaatgaccca tggtatgtcc agtacttccg ttggatcgga
     2281 aatgctttgc aaggcgattt tggtcaaagt ttcttataca aacgctctgt tgctgacttg
     2341 atcggcgaac ggatcatcaa cactttatat ctatcgatct tgacagttgt ccttacttat
     2401 ttgattgctg tgcctctggg gatgcttgct ggccggtatc aaaattcaat cttggataag
     2461 attgtcgtaa tctacaactt ctttagtttt gctgttcctt tatttatctt cggcttgatc
     2521 atgctatttg tttttggtta tcgtttaggc tggttcccaa caagtggatc acaaacacta
     2581 ggtttgcaag gtggatttat cactcaatgg atagaccgtt tgaaatatat tctgttacca
     2641 tcaattaccc aagcattttt ggcgactgcc gtcacaatcc aatatctgcg aagtgaagta
     2701 atcgattcga aatcgctcga ttttgtcaga acagcccgtt ccaaaggggt accgacgaat
     2761 aaagtattca gtcgacatat tttccgaaat gcagcgttgc cgatggcttc tcaaatgggg
     2821 tatgaaatca cttcgttgat tgctggttct gtagttatcg aaaagatttt tggttatccg
     2881 ggagtcggaa aactatttat tgattccatc ggccaacggg actataccgt gatcacatcc
     2941 ttagtattga ttttaggaat cgcgacgcta gtggggacat tactttcaga tatcatcatg
     3001 agtatcgttg acccgcgtat tcggattcaa taaaaccaat cagaaaggag aatggatcga
     3061 tgagtgaaaa aaacaataca gcagttcaag aaagtattcc tcctatgggg atacgaatga
     3121 ttgctcgaga atttaaaaaa gataaaattg ctattttttc attaggtttg ctagtggttt
     3181 tattattagt gatctttatc ggtgcgatgc tgaccgatca agacaaagtg atgtatgtta
     3241 gtatcttcga caaatacgct gcaccaggaa cagtttcgac acaaggacaa aagttcattc
     3301 tgggagcaga tgaaggcgga cgtgatgtat taggacaatt gatcataggt gctagaaact
     3361 ctgttacgat cggatttgcg atcacgatcc ttacttcgat catcggggtt ggattaggga
     3421 tcatctctgg ctactacgga gggatcattg acaacatctt gatgcggatc gttgatttta
     3481 tcatgattct accgatcatg ctgatcatta tcgtcttcgt atcgattatt tccagataca
     3541 atgtctggtc ctttatattc atcatgagtg cattttattg ggtagctaaa gcccgattat
     3601 tccgaagcaa gacattatct gaagcaagaa gagattatgt cagtgcctca aaaacaatgg
     3661 gaaccaatga ttttaaaatc atgttccgcg aaatcatgcc gaatctaagt tcattaatca
     3721 ttactaattt gacgatgaac tttgcggcaa acatcggtat cgagacaact ttgactttct
     3781 taggtttcgg cttgccggca aatgtaccta gtttaggtac attgatcggt tatgcaagta
     3841 acggagaagt cttagtgaat cggcaatgga tctggttacc cgcatcaatc cttattttag
     3901 ttttgatgtt gagtatcaat tatgttggac aagcattcaa gcgttctgca gatgcgcgcc
     3961 aacggttagg ctagtataga agcgaagggg gaaataggaa tgaagaaaac gatttttgga
     4021 tttgcagcgc tgatgtctgc tgtcgttctt gcagcatgcg ggggcggagg tacagatacc
     4081 tctggaaaca actctggagg caacggcaat aacaaagagg aattaacttt tccaattgca
     4141 acaaaaaata atgatgatgc aatcgaagac ggcgaattag aagctgcggt cgcaacggac
     4201 agtcagttta aaggattgtt ccagtgggag ttttaccaag attcatatga tgcagctttt
     4261 atggctcctt ctcatgaacc gctatttgca aacgatgacg atttcagaat cacagacgac
     4321 ggagctgcaa cgcttgatct agatgaagat acgaaaaaag cgacaatcaa agtaaaagac
     4381 aacgtcaaat ggtcagatgg tgaagatgta acggcggacg atgtgatttt cccttacgaa
     4441 atcattggga ataaagatta cactggtatc cgttatgacg acactttccg taacatcgta
     4501 ggtatggaag aatatcatga tggaagtgcc gacacaatct ccggaatcaa aaaaatagac
     4561 gacaaaacag ttgaaatcga atataaagaa gtaaacccaa gcatgcttca atcgggtggt
     4621 ggtatctggt catatgcagc accaaaacat acgttagaag gtgtagcaat caaagatatg
     4681 gaatcaagcg atcaagtacg taaaaatcca gtgacttttg gcccttatta catgagtaat
     4741 atcgttgcag gagaatcagt agaatacttg ccaaacgagc actactggaa tggtacgcct
     4801 aaattgaaaa agatcacgat gaaatctgta ccgatggcaa gtgcaactga agcattgaac
     4861 tctaaattat atgatatgat tttccaaatg ccaacagata cttacgatac ctataaagaa
     4921 attgctggct atacaaactt aggccgtgaa caaacttctt atacttatct aggattcaag
     4981 ttaggtaaat ggaatgcaga tacaaagagt gtggaataca atccagattc aaaaatggct
     5041 gataaatcat tacgtcaagc aatgggctat gcattagata ataatgcagt aggtgaacgt
     5101 ttctatgcag gtttgagaag caatgcgact tcattgattc ctccagtatt ccagtcatac
     5161 catgatgatg agatgaaagg attcacacaa gatctagaca aagcgaaaaa actattagat
     5221 gatgctggct acaaagatgt ggatgacgat ggtttaagag aagacaaaga tggaaataaa
     5281 ctaacaatca actttgcttc gatgtccggt ggggaaacag cgcaaccatt ggcagattac
     5341 tatatccaac aatggaaaga aattggtttg gatgtccaat acacaacagg tcgtctgatc
     5401 gaattcaatt ctttctatga taaattagaa aacgatgatc ctgaaattga tgtttaccaa
     5461 gctgcttgga atacaggaac tgatccaaat ccaagtggac tatggggacc aaatgctgcg
     5521 ttcaactaca ctcgttatga atcagaagaa aatacaaaat tgatcaacga tatcagttca
     5581 agcaaagcat ttgatgaaga gtaccaaaaa gaagcatatc aaaaatggca acaatatgca
     5641 tttgaagaag catttgcgat tccaacgttg ttccgtaatg aagtattgcc agtcaacgac
     5701 cgtgtcaaag actgggattg gtcttatgat gtaccaaacc catgggcaaa tgtttctgtt
     5761 acagcagatt cacgttcata atcactaaaa atgaccgaaa aagggcgatg tcctttttcg
     5821 gttttttgat atttttctgt ttatttctct aatattcagg tcaaggcgct gatttcatga
     5881 cttctccaat aaacggtgtt caaagtccag tttctcggta ttaagtcaaa tttatgcaaa
     5941 aatatggaaa gccattttca caaaattttt tcttcatact cgaaactaaa cgaatttttc
     6001 acaacttctc gtcaatcact aggattatta aagctttact taccttttga ccgaaccatt
     6061 tcaaatttga caaaaaacca gtataataag gaagtatcga aaaaatatcc ataaaaggaa
     6121 tgtggaaaat ggacaaccag ctgacaaaag aactaaaaga aaactataac atcgtttttc
     6181 acgatctaaa tttgcttgaa caagctttta cccattcatc ctatgtgaat gagcatcgca
     6241 atctgcaatt atcggataat gagcgacttg aatttttagg agatgccgtt ttagaactga
     6301 tggtttctca gtatttattc cgtttatatc ctcatttgcc agaaggaaaa ttgacaaaaa
     6361 cacgagctgc gatcgttcgc gaagacagct tgtcgaaatt tgccaaagac tgtcactttg
     6421 atcaatatgt tttgttgggc aagggagaag agaattcagg aggacgtacg cgaccagcat
     6481 tgctttgcga cctattcgaa gcttttttag gcgcgttata tcttgaccag ggattcgaca
     6541 cgacccatgc attcatcgaa aaagtgattt ttcctaaagt caaagcaggt gctttttcac
     6601 atgagatgga tcataaaaca aaactacaag aagtcttgca aaaatcaggt gatgtatcaa
     6661 tcgaataccg attgatcaat gaagaaggtc cagctcatga acgagtattt tggatcgaag
     6721 tttatgtaga tgatcaattg attggcactg gacaagggaa atcgaaaaaa ttagcagaac
     6781 aagctgcggc ggaaaatgca ttggcagcac tgtaaaagta agtgagggaa agctttgtat
     6841 ttgaaacgaa ttgaaatagc cggttttaaa tcatttgcag acaagacagt cattgatttt
     6901 gaaaatagcg tcacagcagt ggttggacca aatggcagcg gaaaaagcaa tattacagag
     6961 gctatccgct gggtattagg agaacaatct gctaaaagtc tgcgaggcgg aaaaatgccg
     7021 gatatcatct ttgccggttc cgatacccgt aagcagctga atattgcaga agtcacagtg
     7081 attttagaca atagtgatca ttatctgcca ttggagtaca atgagatcag tgtaacccgc
     7141 cgttatcgac ggactgggga aagcgagttt ttcatcaata aacaaagctg cagattaaaa
     7201 gatatccaag aattgttctt agattctgga ttaggaaaag aatcgttctc aatcatttct
     7261 caaggaaaag tagaagcgat tttcagtagt aaaccggaag accgtcgtgg gatctttgaa
     7321 gaagcagctg gtgtcttgaa atacaagcag cggaaaaaga aagcagaaca gaagcttttt
     7381 gaaacagaag acaacctcag ccgcgtccaa gacatcatcc acgaattgga agaacagtta
     7441 actcctttgg ccgcccagag tgaggcagca aaggagtttt tacggctaaa agaaacactg
     7501 actcaaaccg atgtctcttt gatggttgct gaaatcaaga cagcaaaaaa agattgggac
     7561 aacaaacaag cacagcttgc gaaattcaat ctagaattag gcaaactatc tgagtcgatc
     7621 caagaacaag aatccatttt ggcgaagcag cgtaaagaaa atgcgcaagc cgatcgtctg
     7681 atcgaaaaaa atcagcaagt attattagat ctttcggaaa aactgaagca gacagaagga
     7741 caaaaagatg ttttgcagga gcggacaaag catacacaaa aaagctcgca agaatatcaa
     7801 acttcattag cagaagcaca aaaaaaggtt aaacattttg aaaagcttca agaaagcttg
     7861 atgaaagcag cagcagaaaa agaaacagag atccaaaaag ctgaagcaaa tctcataaaa
     7921 acacagcaag aattagaaaa ataccaaaaa tcaacgaaag aattattggc agaattaaga
     7981 gatcaatatg ttgatttgat gcaagaacaa gcagctgtag gaaacgaact gaagtatcta
     8041 gaacgtcaat atatacaaga aacagcaaaa agcaagcaga cgttagccaa gcaatcggaa
     8101 gtagaagcat cagtagaccg attgatctta caaaaagaag aattgacaca aaagcaggcg
     8161 cagctaaaat catctttaac tgaaacaaaa gagaagttag aaatgatcca acaaaacggg
     8221 aaaaagttcc aagaagcatt agcaaaagaa cagcctaaaa tgtatcaatt aatgaatcaa
     8281 gtccagcagc tacgtgctcg taagaaaagc cttcaagaaa tccaagaaaa ctattttggt
     8341 ttttaccaag gggttcgatt ggtcttgcag cataaacagc agctttcggg tattgtcgga
     8401 gcagtggctg aactgatcga tgttcctgca gatttcacgt tagctatcga aacagcttta
     8461 ggtggggcag cccagcatgt catcgttgaa aatgaaaaag atgctcggca agccatcacg
     8521 tatttgaaac agcaaagagg aggaagagca acattccttc cactgacgac aatcaaacca
     8581 agacaattac cggctcatat attgacacaa gcagcagctg tagaagggtt tatagggatt
     8641 gccagtgaac aagtcagtta tcccgatcaa atccaaactg tggttcaaaa cctgctagga
     8701 acgatccttt tagccaaaga cttaactagt gccaatgcaa tcgcgcaaac gatccgctat
     8761 caatatcgag tggtttcctt agaaggtgat gtgatgaatg ccggaggatc catgacaggt
     8821 ggagcgaata aacgaggaaa ccaaggcagt ttgtttgtac aaaatcaaga attgaaacag
     8881 ttgactagtg aatttgaaga agcagataaa caactccaag cacaagaaaa aaaagttcag
     8941 gagctgcaac aagaaacagc tcgtttagcc gaagaacaag aagttttgcg tacacgaggc
     9001 gaacaattac gttttgaaga acaagaagcg acaaatcagc tacaaaacat cataaatgaa
     9061 cttgaacgtt ttgaaaaaga aaagcaaatc tcaacttttg agacacgtga actgcagcag
     9121 tttatcgaag attacgaaaa gcaaacgaac gaattgaaag acaaacaaac agatcttgaa
     9181 tcgcaacgac aaaaaatcga cgaagaaatc aaatcgttaa gtcaagaaag cgaccagatg
     9241 gaagccagaa gagcacaagt acaaagtcaa aaagcacaag aacaagcaga tcttgctgtc
     9301 ttgaaagagc agtttaatca tctgcagatc cagctccgcg gtgcccgagt ccaaaaagca
     9361 gaggcaaccg aacgtcaaga agcgatagaa aagcagttgg cgacattgac agcagacttt
     9421 tctgatcatg aagtcacaga agaaagtttg gaaaaacaaa ttaacgaatt atctgctcag
     9481 cgagaaacat taaaagccga gttggcaaaa gccaaagagc agcgagatag aaggcaaaag
     9541 gagatcgata agcttgaagc agtcttggca gagcgtaatc gtgagcaaaa agcacgactg
     9601 tcggaacaat ccaaattaga agtccaaaaa gaccgagctg aaatgatttt agataatcat
     9661 ttgacctatc tgcagtcaga atatcagctg acatttgaga aagcttccca agactatcaa
     9721 gaaacaaccg atatcgaaga cagtagaaca aaggtttcat ccttaaaaga acagattgaa
     9781 aaactgggac cagtaaactt aaattcaatc gaacaatacg aacaagtcag tgaaagacat
     9841 acattcttag caacacagcg agatgatctg ttagcagcga aaaaccaatt gtttgaaacg
     9901 atggatgaga tggatgatga agtgcggaca agattcaaag aagtatttga agctatccgt
     9961 caagaattca aaattgtctt tccaaatatg tttggcggcg gtaaagctga attagtactg
    10021 acggaaccaa ctgatttgct gaaaacaggt attgagattg aagtacaacc tcctggcaaa
    10081 aaactgcaaa gtctaagttt gctttctgga ggagaacgag cacttacagc catcgcgttg
    10141 ctcttttcca ttatccgtgt ctgtcctgtt ccgttttgta tcttagatga ggtagaagca
    10201 gcgttagatg aagccaacgt gaaacgtttt ggtcgttact tgagcgattt ccaagatgac
    10261 acacaattta tcgtagtcac acaccgcaaa ggaacgatgg tcgcagcaga tgtactgtac
    10321 ggagtgacga tgcaggaatc cggtgtatca aaaatcgttt ctgtacggat ggaagatatc
    10381 aatgaagagg cgaaaatcaa cgaaacgaaa gtgtaggaac gaaaatgatc aaattagtag
    10441 caatcgattt ggacggtaca ttattaaatg aacaaaagct gatttcagat gagaataaac
    10501 aagcattagc acaagcaaaa cagcaagggg tcaagatcgt tctatgtaca ggacgcccct
    10561 tagctgcgat ggcgcattat ctgcaagaat taggactggt agatgaaggt gactacagca
    10621 tcactttcaa cggcggtttg gtacaaaaaa atgatactgg tgaaatcatg gaaaagaaag
    10681 tgatggaagt atcagatatc caacgcttat acaaactggc tcagcaattg gatctgccac
    10741 tagatgtttt gtctgacaat gtggttttac agctgcctag tgccccaagg aagcaatcct
    10801 tgtacaatgt gttgaataag ctgctgcaat tccaaccagc ggatataagc gatattacag
    10861 atgaatttgt gcttaataag gcagtaatcg cttatgacca agaagaatta gatcctaaaa
    10921 tcaaagaaat accagcagaa ttccatgaaa tgtatgagat catcaaaaca agaagtatgc
    10981 ttttggaatt tatgccaaaa ggtgttacaa aagcttatgg tatttcttta ttggcaaaag
    11041 atcttggttt gaaacaagaa gaaatcatgg cgatcggtga tgaggaaaat gatttaccga
    11101 tgatccaata tgctggacta ggcgtagcga tggagaatgc tgtgcctttc gtcaaagaag
    11161 cagcagattt cgtgacagcc agcaatgaag aaaatggcgt agccaaagtg atccaaaaat
    11221 ttgtattaga gtagggggag tcaaatggga ttttttgata aaatcaagcg tgcttttact
    11281 ggcgaagaga aaacagaaga agttgaagta caggagaagt acgacaaggg tttagaaaag
    11341 acgcgtaaaa catttggtga acggatgaat gagttgtttg ccaattttcg aacagtcgat
    11401 gaagactttt ttgaagaatt agaagaaaca cttatcggtg cagatgtagg ttttgaaaca
    11461 gcgatacgaa ttaccgaagc attacgtcaa gaagtgaaac tcagaaatgc gaaaaaatcg
    11521 gcagaagtcc aaaatgcgat catcgagaaa cttgtggatc tctatgaagc ggaaggaatc
    11581 aatgaagtaa atgaactaaa tatccaagaa gacggactaa cagttatttt gtttgtcggt
    11641 gttaatggtg tagggaaaac aacaagtatt ggtaaacttg cccatcagtt caaaaacgaa
    11701 ggtaaaaaag tattgatggc agcagcagat accttccgcg ctggagcaat cgaccagtta
    11761 gttgtctggg gcgaacgcgc tggtgttgaa gttgttcgtg gcaatgcagg aggcgatcca
    11821 gcagctgtcg tattcgatgc tttggaaaga gcaaagacag agcaggcaga tgttttacta
    11881 gttgatactg caggccgact gcaaaataaa gtgaacttga tgaacgaatt agaaaaaata
    11941 aaacgagtaa tccagcggga attaccagaa gcaccccaag aaacacttct tgtattagat
    12001 gcaaccactg gtcaaaacgc gatggttcaa gcaaaacaat tcaaagaaac aacagatgtg
    12061 accggtcttg ttttgacaaa attagatggt acagcaaagg gcggtatcgt acttgctatc
    12121 cgtaatgaat tgcatttacc agtgaaattg gtcggtcttg gtgaaggaat cgatgacttg
    12181 gagccgtttg atccaaatga ttttgtcgtt ggattgttca aaggattact aaaagaagaa
    12241 taacccatgt ctaaaaagca ggagctgtga caaaagttgc agctccttgt ttgaatgatt
    12301 gtttttaaca tagctgtgtt tttgatgcct tcatttttat acttatttgt aagcggttct
    12361 caaacaattt cgttcttttt cttagacttt ttgattataa ttagattcat atgaattgga
    12421 ggtcacttaa tgatgaattt taagcaatta ttattgcatg tcaatgcgcg cccttttatc
    12481 gaccaagctc gatttggtat agaacgggaa ggacagcggg ttgatcttgc aggaaatcta
    12541 gcaaaaaccg atcatccagc aatctttggc gatcgatcct atcaccccta tatccaaaca
    12601 gattttagcg aaacacaaac agagatgatc acccctgtta ccgattctat tcccgaatta
    12661 tttcagtatc tcgctgctgt ttatgatgtg actgctcgtt ctataccgaa agaagagatg
    12721 atctggccat taagtatgcc acctgcctta ccggaaaaag acgaagagat cattattgca
    12781 aaattaaaaa atttcgaaga tgtcttgtat cgacgttatt tagcaaaaga atacgggaag
    12841 cgaaaacaga tggtaagcgg tattcatttc aattttgaat ttggcgatga gttgctaaga
    12901 acattgttca gccatcagga agaatttcaa gatttttccg aattcaaaac agaactttat
    12961 ttgaaaacag cgagaaactt tatgcgctat cgctggatga tcacttattt attcggtgct
    13021 tcaccaatga gtgagaagaa ctacttttta gatgaatcac atccgcaaga acctgttcgc
    13081 agtattcgca acagtgcgct gggctatacg aatcatccaa atgtgaaagt ttcctatgct
    13141 tctatgaaac agtatttagc agatatcgag cgaatgatcg aagaagggaa actttcggag
    13201 gagaaagaat tttatacacc gcttcgtttc cgaggcggaa agaaagtcgc agatttagca
    13261 acaacaggtg ttcgttatat tgaattgcgg aatatcgatt tgaatcctta tgcaagattg
    13321 ggtatcaatc cagagcaagt tcggttctta caattattcc tgatgtacat gttatggaca
    13381 gaagaaaaag aagactgtga ccaatgggta gcagaaggta cgactcgaaa taacaaagta
    13441 gcactagaac aaccatcaga tcaaacagaa tttcatcaag aaggtagaga aattcttgaa
    13501 ggaatgaagc aaatgctggt tgaattggat tggttggatt ctctttattt agtagaggaa
    13561 gcattgactc aaatggatca tcctgaacaa acgttagcag cgaaactcta tcaagaagca
    13621 cagctatcga gtcagcaaga agttgctgtg gcattgggac atcaatatta taaagaaagc
    13681 catgaacgtc cctatcagtt ggccggtttt cgcgaaatgg aactttctac tcagatattt
    13741 atgttcgatg ccatccaaaa aggtgtccaa gtcaaagtat tagatgagtc ggatcaattt
    13801 ttgcgtctgc aattccaaga ccatgtagaa tatgtgaaaa atgcaaacat gacaagtaag
    13861 gacagctata tcgtcccact tatcatggaa aacaaaacag taacgaaaaa agtcttaaaa
    13921 gaagctgggt tccgggtacc aggaggcgca gaattttcat ccatggaaga agcggtaaaa
    13981 gcttatccga gatttgccga gcaggcattt gtgatcaaac ctaaatcaac caattacggg
    14041 ttaggtatca cgattttcaa ggaaggagct agtctggaag attatcaagc aggtttagcc
    14101 attgcttttc gtgaagacag ttcggtttta gtagaagaat ttatgccggg aacggaatat
    14161 cgtttctttg tgatcgacgg agaagtccaa gccatcatgt tgcgagtccc tgctaatgtt
    14221 attggtgaca gtatccgaac agtgaaagaa cttgttgaag aaaaaaatag tgaccctttg
    14281 cgtggaacga atcatcgtgc acctttagaa ttgatccaat taggtgaatt agaacaattg
    14341 atgttgaaag aacaagggtt gacgatcgaa tcagttcccc aagccaatca aattgtttat
    14401 ctaagggaga actcaaatat cagtacaggt ggtgattcga tcgatatgac tgatgaattt
    14461 tctgaagctt acaaaaaaat cgccgtttct gcggtagaag cactaggagc taagattagt
    14521 ggtatcgatt tgattatacc agataaagaa atcgatccta caactgataa aaaagcatat
    14581 gggatcatcg aagcaaattt caatccagcc atgcatatgc atgtttatcc ttttgcagga
    14641 aaaggcagaa gattgacgat gaatgtattg aaattgttat atcctgaagt attttaaaag
    14701 aaaaagcttt tgacagattg tcctatttga tgtcaatctg atcaaaagct ttttttgcat
    14761 gtaaaaattt atgtgttttt tcgttttaaa ataaacgatc ccagaagctt tttttctttt
    14821 ttggtttttc tttttcagct ggcgaagagt tttcttctgg gtattttttt tcgatatcaa
    14881 tcacaggttc atttactgct tcttttgctg ttaagagcaa tccgaattcc tcaggatttg
    14941 cagtgacgta atcgttgact acagtgaaac ggctattgct tttcgttgct agctggatat
    15001 attggttttg gacagaaagg ggtagagccc cattcaagag tatggaagca tctggatgtt
    15061 ttttgagttc ttttaaaaag ttttctttgt tttttggttg gatcatttca gcaacagtca
    15121 tactaagata gcagcgttcc ctgaatgtcc ctaaatattt atgctgttct tcagggttca
    15181 ctaaaggtgt accataaagt cccttatcca aatggctttt tacatcatct tgtgccataa
    15241 aaaataccct ccttcttctc tttgtctttc ttacgattat agcatattcc caataatacc
    15301 taaaacatat gaaaaagcgg ttgcttttgt tcaacgattc acttaaaata agaatgaaaa
    15361 tcattctcaa ttagaaaggt ggattggatg cgctacggac gactagtagc attattagtt
    15421 attttaagta gtatttcatt gttcatcgga gtatcgaatg tacaattgtc agaactgctc
    15481 cagttagatg ggcaaagctt acaaatcttg ctagtgactc gtttgccacg aacgatttgt
    15541 ttgatccttg tgggagcgac cagtagtatt tgtgggttga tcatgcaaca tttgacccaa
    15601 aataaatttg tttcaccaac gactgcgggc acgatggata gtgcgcgttt aggtatttta
    15661 gtggctatga ttttcctacc tggtgcatcc ttgattgtcc gatccttgac agcattttgc
    15721 tttgcttttg caggaacatt gcttttttta tcccttacgc gattgttcct ccagaaaaat
    15781 caattgatgc ttccgttgat tggagtcatg ttagggaata tcattggttc agttgctact
    15841 ttttttgctt atcaattcca gttggtacaa aatatgactt catggcttca agggaatttt
    15901 gcgactgtga tacgaggaaa ttatgagtta ttgtatgctg ttgttccatt gttgctcttg
    15961 gtttggctat ttgcttaccg atttacgatc attggtctgg gcgaatcgtt tgcagtaaat
    16021 ctgggaatag attaccagaa gatgcagttt ttaggcattg gcttagtatc attggctagt
    16081 gcagtcatgt tgatcatggt aggaagcatt ccttttatcg gagtgatcat tccgaatctt
    16141 gtctctagaa tatatggaga tcaagtgcac aaaacaattg gcgtaactgc tttagcaggt
    16201 agtttgttct tagtattttg cgatcttgtc gctcgcgtgt tgatttttcc ttatgaaata
    16261 ccagtcagtg tgatcgttgg aatcatcggt ggggctatct tcctttatct tctgataagg
    16321 ggacgacgat atgcttaaaa aaaagccatc tatttttatt ggtatgcttg ttcttgtttt
    16381 atttgttaca ggaatgtact tgacgatcca tacatatgga aactggcatt ttgcatgtgc
    16441 attgaggagt aagaaaattt ttgcatttat ccttgtctcg ctagctgtca gcagtgccac
    16501 aatcagcttt cagacaatta cgcataacca gtttttgact ccttcagtat tgggacttga
    16561 gtcgttatat gtccttgtcc aaacggtcct tttcttcttt atcggaggag tgacgatgct
    16621 tcagcagaca ggtacagttt ttttcttatt gaacgttggg ctgatggtcg ggctgagtct
    16681 attgttattt ttctttcttt tgaaaaaaat gagagcgaat ctttttttat tactgatgtc
    16741 agggatgatt ttaggtacgc tttttggtag tgtcagtacc tttttacaag tcatcatgga
    16801 tccgaatgaa tatgatttgc ttcaaggcag attatttgca agctttggca atatccagag
    16861 tcagtatctt ttgcctgctt ctttgatcat tatcggctgc tggtacctgt tatttcgata
    16921 tcgacatgtg ctagacgttt tccatctcgg aaatgaacaa gcagtaaacc tcgggataga
    16981 cacagatcgt tttgaatttt tgattttatg ttgtgtcagt cttttgacag ggacatcaac
    17041 ggctcttgtg ggtccagtta cttttttagg gtttattgtc gcaaatatca gttatcgtgt
    17101 cttttctact tatcgtcatg gtcagctatt tatcggaagc tttctggtag ctatgctgtt
    17161 tctgacagga ggacagctcg cagtagagca gattttcggc tggaatacaa cagtgagtgt
    17221 cgtcgttgaa tttgtcggag gaatttattt tgtcacaaaa ttgattcgcg aaaggaagag
    17281 tatcctatga ttgatttaca aaaggtcaat aaactgtacc atggaaaatc agtggttaaa
    17341 gatgtacagt taacgattcc tgaaaagaaa ttgactgctt ttatcggtcc aaatggtgct
    17401 ggaaagtcaa cggtgttgtc gatgatcagt cgtttgatac caaaagatac aggtgaaatc
    17461 tatttagacc ataacgaagt aaaggcttgg aaatccaatg aattagccaa aaaattatcg
    17521 atcctacgac aatcgaatga aataaatgtc caaatcaccg tgaaagaatt agtagaattt
    17581 ggacgatttc cttatacgaa aggaaaattg acgacaaaag acgaggaaat cgttcaggaa
    17641 tcactggaac accttgggtt agaagaaata gcggatcaat cgattgacac tctttcaggc
    17701 ggtcaactcc aacgtgcgta tattgcaatg gtgctagcgc aagacacgga ttatatttta
    17761 ctggatgaac ctttgaacaa tctagatatg aattttgcgg ttcaaatcat gcagatttta
    17821 aaaaatttag tacaagaaat cgggaaaaca attgttattg ttcttcatga tatcaacttt
    17881 gctgcaagtt atgcagacga aattgttgca atgaaagatg gacagttatt tacgcaagga
    17941 acgacccaag aaatgataaa aaaagatgta ttggatgaat tatacgaaat ggacatacgg
    18001 atttgtgaga ttgaaggccg cagattctgt ctttatttct aaaactaaca ttaggagaga
    18061 agagatgaaa aaattagtag taggtatctt gattctagca tcatttggtt tagcagcatg
    18121 tggaaatagc aacaacacca gtcaggcaga cacaaaaaaa agcagcacac aaactgaaac
    18181 tacattgacg ataacagata gtaatggaga ccaaatcgag gtgccaaata atccagaaaa
    18241 agtcgtcgta ttcgacaatg gttctttaga tacgatggat gctcttggtg ttggagataa
    18301 ggtagttgga gcagctacaa gcagccttcc tgagtatctt tcatcctata aaaaagtaga
    18361 atcagcaggt ggaataaaag aaccagactt agaaaaaatt aatcagcttc agccagatct
    18421 aatcatcatt tctggccgac aaagagattt tcaaaaagat ctaagtcaaa ttgctccgac
    18481 cattttcctt tctttagatg cgaaaaatcc atgggaatct ttccagcaaa atgtcactgc
    18541 tttaggggag atctttggta agcaagaaga agctaaaact caattagagg aattatctag
    18601 tgcaatcgat cagacgaaaa agaaagcaga agctactgac aaaaaagcac tagtcacact
    18661 tgtgaatgaa gggcaattat cagcctacgg atctggttct agattcggtt tcatccatga
    18721 tttatttggc tttgaacaag cagatgatca aatcgaagca tccactcacg gtcaaagtgt
    18781 ttcttatgaa tatgtgctgg aaaaaaatcc ggatatctta tttgtagtag acagaacaaa
    18841 agctattggt ggagacgaca gcaaagatga tatttctgcc aatgaactgg tagcacaaac
    18901 gaatgctggt aaaaatcagc agatcatctc ccttgaacca gatgtctggt atttaagcgg
    18961 gggcggttta gaatcaatga aactgatgat cgaagatgtg aatcaagcat ttaaatagca
    19021 taaataacag aggattaaac tctcatacta tgtaacaata atgtttctta cattcttaaa
    19081 tagcaagagc ctatcctcaa agaagttatc aaaaaccatc cgtaaaatcg tattgatgat
    19141 tttacggatg gtttttattt atttgagaaa tcttttttca acgtgaattc attatctaca
    19201 tcatacgggt tgattctaga atggggagtg gcaaaaaata gtgtgatcca ttttttcagc
    19261 atcaagatcg cctcctttga tttgaatcaa aggtacaaag cgaaacttag ataaaactta
    19321 aatttagata tttttatttt gtaccgatct cttctttaaa cgatgttcca tctgctgctt
    19381 ctcggcaata agtccactag actagaaaat atgagaagct attttctgtc cagcgttctt
    19441 attactcaaa gcaaatcgca gttgtcacaa tctcttctaa acgatgttcc atctgctgct
    19501 tctcggcaat aagcccacta gactagaaaa tatgagaagc tattttctgt ccagcgttct
    19561 tattactcaa agcaaatcgc agttgtcaca atctcttcta aacaatgttc aatcagctga
    19621 ccttcggtat tagctcaaag cactgatttc acaacctcta tttaggcatg tgtctcagca
    19681 agcggttgat agttgatgat ctgcattttt cgataaaaat cggcgggaag cttactccac
    19741 cgttttaata attgatagaa ataactctct tctgctttga ttttatactc gcttaatatc
    19801 aatccaaaac tattcgtttt ttttgaagct aattttttat aaatatccaa tgctttggtt
    19861 ttatcttcat tgacaaagag tgtttttact tcaatataag aaccctcgat attttgtgtt
    19921 tcttcgataa aatagatgtt ttttatatat tccttcatag tgattcctcc aaagaagtct
    19981 tttatttgat aagtttactc taccgaagag ttgttaataa tccgtgaaca aaaagtaatt
    20041 ctttttccaa tagttgttaa aggtttttta ttttttatag tattttttgt tatttaagaa
    20101 aggaataagg ttaaacaaat aacaggttgc tttttgggtc tttttccgtt caagaaactg
    20161 aacgaagaaa agggaaagtt gtctcttttg tgataagaga aatcataata aacgaatgac
    20221 ttactttcca ataaattgag aacagtcaga accagacaaa ttagttgcat ctgatgaata
    20281 aagtgattat tctatgacat gaggtgatac agatgaaatt agaagtgaca aaagaagcac
    20341 aagaagtatt gaagaataaa ttagaagcag acgatcaact tttattagat atcgaaaacg
    20401 gtgacggtcc atttgcagaa agccaagtca gttgccaatt ggatacggca tttcgattga
    20461 tcattgtcaa aaaagataca caaacagatc taagtcttta ttctgtagtg gctgatacac
    20521 cagttggacc aatcaaaatc aaagacagtg caatacttta catggatgat ccatccacac
    20581 ttgctttaga accaacttat aatagtttac aattaaaagg accaagcggc ttgagaaaag
    20641 gcaacttgca agttgttcga aaagactaga gggataaaat gggaaaattg gcgatcatca
    20701 gcgacctaca tgtggacatc aataaattcg gcgaatcaga gctgatgcag ctttggcaag
    20761 ttttgcaaaa gcacaagatc actcggcttc atctagccgg agatacggct aataaagtag
    20821 accgttgcct agctgttgtc gaatttttcg tcaataaagg attatctacg acatttcatt
    20881 tcggcaatca cgagttggca gatgtgccca atgaacagat gatggaccat tttccagacc
    20941 cacatttttt aaatgaacgg tatattgctt taaatgagca gaccgttctt ttagggatga
    21001 atggctggta cgactatcag ttttccgaat tgaaagatta cgaggcaatc gtacgaatga
    21061 agcgtttgta ttggtatgat cggttcatcc agcgtgggaa aacagatctc gaggtcaatg
    21121 cagaaatgct tgcagctgca aaaaatttgc tagaccagct ggaagcaaaa aaacttgagg
    21181 tgattttatc cactcatttc gttcctaaac gggcatttat catgtatcaa tctgctcctt
    21241 atgagcgttg gaacaaatta aatgcatttt taggatcaga atcattcgga gaattacttg
    21301 accgttattc aaatatcaaa caagtagttt ttggccatac gcatcgtcgc tttgaagata
    21361 aatccatcgg tcacacgatt tacagctgca gaccttttgg ttattattat gaatggcagc
    21421 tgacccgaga ttttgtcttg aaagaacagt tgctagacag ctatgatcct atgaaattac
    21481 gtgtcctctt gcgtgcccat cacccagctt ttcaggccta tcaaacacaa catttgcaag
    21541 aggaatttga acaagcgatg acaatcgttc cgtattgaga cagcattagt aatgtgtaaa
    21601 agaaaatacc ttgtaaaaca taaggataag taagagcagt agatccattt atcgtggata
    21661 tgctgctttt tttgcggaaa ataatcagcg aatgtttatt tgatcggatg atttgtaact
    21721 cgcagagtac tagatgcaag cgtgtattct ttttttgaac gataatcaca aaaaaaaata
    21781 taatatacat tttttattta attataatta atattgattg aagtctaggc agtcaagtca
    21841 cattttgata gataggaggg ggacttacga attattttaa aggctatgac agctgtattt
    21901 ctagattgtg tttgcatcaa gttgcaataa aaactagaaa tcaaatcggg ctgataatca
    21961 tttataacta atcgatacat aggaccaaat ataggtctat gttcttttat ttcataagta
    22021 tcgtaaaaca gaattttgct atggattaat ccaatcgact gatatgttta gtaaataaag
    22081 aaagaggaat gtcaatgatg aaaaaagaaa tcgtattaac agcagcaatg atgttattca
    22141 gcatggtagc aagtacgact tttgtttctg caactgaagt atacccaaag gaatataaca
    22201 cagaaggaac gattacattt gaagcaggag atgagggtgt aactcctcct gttgatccag
    22261 agaatcctga tcccaataaa cctgtcgatc catcagatcc tccaagccct ggaacaggag
    22321 gggcattatc gattgattat ggatcaaaat tcaaatttgg gactcaaaaa atttctactg
    22381 cggataaaac gtattatgca gctgctgatg tgatgaacga tgggtctaga aaaccgacat
    22441 atgtccaagt gacagatagg agaagtacct tatctgggtg gaaattaagt gtctctcaac
    22501 cagaacagtt taaaactgcc agtggggatg aactagttgg agcacagctg aaatttacga
    22561 aagggcaggc tgtttctttg gttgatccaa catatacgcc gcaaacggtg aattctgaat
    22621 taacgttgac accgggagga aacaatacgt tagcaattaa tgctaaatca ggaacaggtg
    22681 tggggacttg ggtctatcga tttggtgcaa atgaaaatga aaatcaagat gcggtacagc
    22741 tttcggtacc cggtaaatct gtcaagttag cgcaacaata ttccactaaa ttagtttgga
    22801 cattagaaga tacacctaac aactagttta ctgaaaagaa ctgttaaaaa taaatacgta
    22861 gtcatattgt cttgcgaggt aatcgagcaa aaattgtcaa aggctaggct aaatttgttt
    22921 ggatacgaat agttcatcta ggaatttaac gatcaggagg aaaagatata ttgaaaaaga
    22981 ggaggatcgt gctcatttta agcagtctct tagtgactaa tatctttccg atcatagggt
    23041 actctttgga attgaatcag ttggagcatg gaaatagaag agacgaagaa agcaaactca
    23101 cttcgacatt cgacagttta atagaatcca accagacaca agaaagcagt gaggatttaa
    23161 gtatttcgag tagtggagag accactgaca acgtagaagc tgagggttcg gacaaacaag
    23221 gactagaaga tgcaccaatt tctgcggttg agctgcctga cgatcccaat attatttcta
    23281 tcgataaaat ttttcaaaca cctatcggta ctagcacgtc catattggaa aatgggaagt
    23341 tactgcagtt gaacccagca gaaaggtctc aaagaggagc tatttggtca aataagaaga
    23401 ttagtttact ctcggatttt acatttaaat cttatttata cttaggaaat caacgagata
    23461 gagcgggaga tggcatgacc tttacattga ctggcgatcc tagaatggct agtaatccca
    23521 gtcaagttat tggatcgcca ggtatgggaa ttggctcata ttctactcgt tctggccaac
    23581 cttacattgc gaatgcgctc tcgattgagt ttgatacgta taaaaatagt ggttcttctg
    23641 atcgaatgga tcgagagata actgctgata atagagggca tggacatgtc gcttttgtca
    23701 cgcctaaacc aaataataat aattattctg gagagcatac tggcgtgacg gtagctccta
    23761 catttctttc taatggcaca tggcgcttgt taataattaa atgggacgcg gagcaaagaa
    23821 gtcttactta tgatttggaa ggtgtcggtc gctcttctcg gattatacct gatctcatta
    23881 ggcagtttgg ttctacagaa gtaaattggg ggtttacttc ttcaacaggt actttttttc
    23941 aagaaaatgc tgtcgctgtc acgcgacttc catcgaatgt cacatcaaca gctgatgtaa
    24001 aagtcaacga tagtgattat ggggccatcg ctgaagctgg aggaaacgat aagataacta
    24061 tcagaaatac attgaaggtc gagggggatt ttcttgaata taagaaaatg cagactagta
    24121 tcgacctccc acaagaatta actattcccg agcatatctt gatcaatgga aatcaaattg
    24181 atgccaaaga tatcttgata accggaaatc gagtcacgct aaatctgaca gattatttta
    24241 ttgctggaga tacgttaata atcgaattgg agacaacttt gcaggaagta attcctgaaa
    24301 aagtactcac tatgcatttt gaataccttg aaaacgggaa tttgattgag caatcgaatg
    24361 aaataaacct aaagatcgca aagctgaagg agatagatat ccatgtttat tataaagata
    24421 aagacagtca gattgatatt gctgaaatga aaacaatcac tgggaaaata ggagagaagt
    24481 ataaagaaac tcctattgat attgaagggt atgtttttga ctcggattca gcgaatacag
    24541 aaggcatctt ctccgaaaat acagaggata tctattttta ttacagaaaa ggcaaacttt
    24601 atctctcaac tgctcctcaa tatgtcaatt ttggaaaaca taaaatatcc agtagaccat
    24661 taagtgaatt cggacagttt tcaggtgggt tgaaaattat agatgaacgg gcttttggaa
    24721 gttggaaatt acaattgaaa caagagaaag ttcttacaaa tggagatttt gagcttccag
    24781 aagctctttc ctttgttacc tctgaaaata caacggttat agggacatcc gctgttacga
    24841 ttttcgaaag tgatcaaaag ggtgaaagcg atttgtcctc tcttttagat tctacagctc
    24901 atcgtggaat cagaatagat attcctgtag aaaaccaaag aatcggaacc tttgagggga
    24961 aactatcttg gatacttgca gatgtcccag gaaattaaca ggaagagaag aatataacaa
    25021 aattattgag tttcaagaag ggcacaggta ccataggctc ttgtgtccca cagagacaag
    25081 attttgttat agtcttctct tacatatgat taaaggagcg attttcttga gaccaaaaca
    25141 acaattattt ataacactcc tagttatttt aggggcactt tttaacaata tatcagtgtc
    25201 agctagtgca tttaattttt cagtgacgcc gataacttca gagaatcaaa tcgacaagag
    25261 aaaaacttac ttcgatcttc aacttgatcc ggatcaggaa gtagaagtaa aagcggaatt
    25321 gagaaatgat acagaaaaag aagtgaaaat cgatatttct gtgaatagcg caaccaccaa
    25381 ttcaaatgtg atggttgaat acggaaaaaa cgagattgaa aaagacatga gcctgatctt
    25441 tgatctggta gattatgtga gctatccaca gatagtgacg ctaaaaccta aaagtgtcca
    25501 aaccgttgct tttcatgtca ggatgccgaa tgagcgattt gatggtgtat tggctggtgg
    25561 gatcacattc caagaaatcc agacggaaaa ggaccaaaca gaaactaagg atcaaagctt
    25621 atcgattgag aatgaataca cctatattat tgctttgttg atgcaacaga cactgaacga
    25681 agttgctccg aaccttactc ttcatgaagt taaaccagat caaatcaatg caagaaatgt
    25741 catcttagca aacgttcaaa atgatcaaaa aacctatatc aatcaagtag ttattgaaac
    25801 aaaaattaca aaaaaaggac attctgaagt tttatatcaa gaggaaaaag aaggattgca
    25861 gattgcgccg aatacaaatt tttcttttcc aactgcttta aatggtcaac cgctaacccc
    25921 aggtgaatat caccttacaa tgactgtttt aggaaatgaa aatgaaaatg gaaaattttc
    25981 gagaaaaaaa ggaaatacta cgatcaacta taccaatcaa tgggtatttg aaaaagattt
    26041 tacaatagac ggaaaagtag ccaaggaatt gaacacgacg gatgttacga ttaaaaaaga
    26101 caataattgg atttatatct tagtagcttc acttttctta ttgtttattt tattatgcat
    26161 acttttgttt gttttgagaa aaaaagaaga gaaagaaaag taaggttaag ataacaaata
    26221 gtaaattttt attattgtag gatggttggg ctctttttat aacaatataa aatataccat
    26281 tttattaata aaaatgcata ctagtaaatg atataattct aataacaggt ttgatcgcga
    26341 gaaaggccaa ataaaacgct ctccaaaatg ttaaaaaaaa gacaggacga tgtatattat
    26401 acaaacaaga atcgctgaca acagtgactc ggatccagga aatcagtttt atccccagct
    26461 agttggtgaa tgcatggaaa gtaatatacg tagaaagagc tgatgactaa tgaattatga
    26521 gtttttttta agcaaagaag atcacagaag ttattcatta cttaaatatt tagaagcaag
    26581 ctcaaattta tcagagtcaa tatcgaatgt tcaagaagag ttgtcgctat cgacatttct
    26641 cttgaaaaaa acgatcgata agctgaaaca tgatttacaa aagttcgatc tagagaaaaa
    26701 tttgcgagta accgtcagtg aattggatat atgtctggaa attaatggaa aatgttctag
    26761 caaagctctg ttatctcgtt atataacgga ttctttatct atgaaaatgg tattggcttt
    26821 ctttcaggaa aaatatatct cagtagaaaa ttttgctaaa cagcatcacg tgagttattc
    26881 tgtggcttat aaagtattac aaagactaaa aagaaatcta aaaaaatatc aaattttttt
    26941 tgaaaagaga aagttg
//
LOCUS       DAFBVQ010000034        26900 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.034, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000034 DAFBVQ010000000
VERSION     DAFBVQ010000034.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.034"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(38..1144)
                     /locus_tag="LLC22_001638"
     CDS             complement(38..1144)
                     /locus_tag="LLC22_001638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase P family protein"
                     /protein_id="HBK5434920.1"
                     /translation="MNNVKINELRQWMAQHQVELAYISDPGHIAYFSGYESDPHERVL
                     ALFIPLEQDPFLFTPALEVEDAQNSSWAYDVRGYLDSENPWEIIGKELRTRYGQPGNV
                     GIEKNALTVERFDAISDILTGTDSYTDLTSIIQRLQLIKTLEEKDKLIEAGKWADVAF
                     EIGFKAVKEGVTEQAIIAEIEYQLKKQGVSQMSFDTLVLAGANAASPHGTPGNTKISP
                     NELVLFDLGVVWNGYCSDATRTIAYQKPTDFQEKIYNITLEAQLAAQEAVRPGVTAGE
                     LDQIARNVINSYGYGEYFNHRLGHGIGTTVHEFPSLVEGNDLVIEEGMCFSLEPGIYI
                     PEKVGVRIEDCVYVTSDGCVPFTTTPKELLVLEK"
     gene            1354..2355
                     /gene="ccpA"
                     /locus_tag="LLC22_001639"
     CDS             1354..2355
                     /gene="ccpA"
                     /locus_tag="LLC22_001639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="catabolite control protein A"
                     /protein_id="HBK5434921.1"
                     /translation="MEKQTITIYDVAREANVSMATVSRVVNGNPNVKPATRKKVLEVI
                     DRLDYRPNAVARGLASKKTTTVGVIIPDVSNMFFASLARGIDDVATMYKYNIILANSD
                     GNDQKEVNVLNNLLAKQVDGVIFMGHHITDEIRGEFSRSKTPVVLAGSIDPDEQVGSV
                     NIDYVSATKDAVNKLAKSGNKKIAFVSGALIDPINGQNRLKGYKEALSENNLPYSEGL
                     IFEAQYNFKDGLSLADRIHNSGATAVYVSDDELAIGILDGLLDRGVKVPEGFEIITSN
                     NSLLTEVARPRLTSITQPLYDLGAVSMRLLTKMMNKEEVEEKTIILPYGIEEKGSTK"
     gene            complement(2692..5037)
                     /locus_tag="LLC22_001640"
     CDS             complement(2692..5037)
                     /locus_tag="LLC22_001640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300682.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein"
                     /protein_id="HBK5434922.1"
                     /translation="MPRKNTRKKQNRRKKEKWFVPKIIFRVFQSLTVFITVLLLMFAA
                     LGIGIGAGYFAYLVEDTQLPTKKALQTELGNITETSKIVYADNTEISKIQTDLMRTTI
                     SSDKISPLLKTAIISTEDEYFDKHQGYVPKAVLRALVSEATGIGSSGGSTLTQQLVKQ
                     QILTDETTFKRKANEIILSAQVEKYFSKDEIIATYLNVSPFGRNNKGQNIAGVQEAAR
                     GIFGVDAKDVTLPQAAYIAGLPQSPITYSPYTNTGALKEDLSAGLARKDFVLFSMYRE
                     GQITKEQYEEAKAYDLTKDFLPQQIAEQTDREFLYYTVMNEATRIIAQQLAEKDNADM
                     SDSSVSDAYYQKAQQTIQNKGYTIHSTIDKDVYAALQNGVENYGYMLDDGAGSQVETG
                     NVLMDNRTGRIYGFVGGRNYSQNQNNHAFDTERQAGSSIKPVLVYGPAIDMGLIGSES
                     RVSDYATTWQEGENAGEKIVNATNEGSNTFQTVRESLEWSNNIPAYHLYQDVLNSGGS
                     KQYAYEHYLAKMNYPANDNWGVESAPLGTVDVTTLQQTNGFQALANGGVYEEGYIIDS
                     ITDNAGNVIYKHESNSVRIYSEATASIMNDMMRSVINAKITTPFKDAISSLNGNLGKA
                     DWVGKTGSTNEYRDSWLIVSTPSITISSWAGHDDNTGMDSKARIRSANYLANLINQAY
                     QAKPDIFGTDEKFELSSDVMKKKVSGFTGQTPGKVTVNKKSIQTPGKTVESLWAKNGP
                     KKSAFKFGVGGTDENYTDYWNTASAYARANQATKESDEKDD"
     gene            5316..6218
                     /locus_tag="LLC22_001641"
     CDS             5316..6218
                     /locus_tag="LLC22_001641"
                     /EC_number="3.1.21.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334132.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxyribonuclease IV"
                     /protein_id="HBK5434923.1"
                     /translation="MLLGSHVSMSGKKMLLGAAEEAASYGSSTFMIYTGAPQNTRRKA
                     IEEMNIDAGKAYMAENGLTNIVVHAPYIINLGNTIKPEMFPFAVQFLREEIVRAEALG
                     ATQITLHPGAHVGAGTEAGIARIIEGLNEVLTKEQTAQIALETMAGKGTEIGRTFEEL
                     AQIIDGVKLNEKLSVTFDTCHTNDAGYNIKEDFSGVMEEFDKIIGLDRLKVLHINDSK
                     NPQGSHKDRHANIGFGTIGFDTLNKIVHDPMFDNISKILETPYVGKDKKKAYAPYGKE
                     IAMFKAQIFDPEVFPELLAEEVIL"
     gene            6431..8206
                     /locus_tag="LLC22_001642"
     CDS             6431..8206
                     /locus_tag="LLC22_001642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosyltransferase"
                     /protein_id="HBK5434924.1"
                     /translation="MLNTLKPLINQLKKKHTYFILGIALLFTIIRLYLYSKAIYGTDM
                     SATYDDQLLIRYAQNILDGKWLGEYTTTTLSKGISYSLFLVLAHKLHLSYAVLFGMFS
                     IFASILVALAFKPIVKNKYLLLSFYFYFLFSPISFTHEYSTRTYRNALVIPAVEIIIA
                     CLLAIYYRKYGSSRKLLPWFLGLSVAFPFFWFIREDSIWLLPFTVVALGISFVQILLG
                     QDFSFKEVKKLKKRLFLLSKREWLKLSLFLLPIVGFSIVYQWIEYKNETTYGIATIND
                     RSSGEFGRLMKQLIRIDDETNLNKENSEIWVSHAALNKALAASPTFHTVSTRIDELYT
                     THAWTQGGKVKELPGDIIFWALRDVVSESGYYQNNAKETNDFWKKVNQELEEAYHKGT
                     IKKKKEFYLMGSGDGKTMSDLPIVFDFLQSGYAYAWRYKDFHQGGNYSFGTQEQVKQA
                     QELLNLPLMENWIDSNEPRTPNFQLTKSAKVANVIIKIYQVLAIPVLIASIAGILLMI
                     LGTVFAKADRAYYSSSLIVVTGLILTQLVFLFGVSWFCSYAPEKKDYFLSVYTGAGVP
                     LTQFIVVTSMLVFSKLNLKKALSSK"
     gene            complement(8272..9858)
                     /locus_tag="LLC22_001643"
     CDS             complement(8272..9858)
                     /locus_tag="LLC22_001643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Nramp family divalent metal transporter"
                     /protein_id="HBK5434925.1"
                     /translation="MNNQSNKQFHKHRLIEHTNGLSLAEVNGTVDVPKGKSFFKTLLA
                     YSGPGALVAVGYMDPGNWSTSITGGQNFQYLLMSVILMSSLIAMLLQYMAAKLGIVTQ
                     MDLAQAIRARTSKTLGVILWILTELAIMATDIAEVIGAAIALYLLFDIPLVIAVFITV
                     LDVFVLLLLTKVGFRKIEALVVCLIFVILFVFVYQVGLSNPDWHSLFAGFIPNSHTFS
                     DSPVIGGETPLTGALGIIGATVMPHNLYLHSAVSQTRKIDHQDEEDVAQAVRFSTWDS
                     NIQLSMAFLVNALLLIMGVAVFKTGSVQDPSFFGLYEALSDPSAMSNGILIAVAKSGI
                     LSTLFAVALLASGQNSTITGTLTGQVIMEGFIHMRIPIWLRRLVTRLLSVIPVLICVL
                     FTSTKGTIEEHTALNNLMNESQVFLAFALPFSMIPLLMMTNSQAEMGSRFKNSFIVKL
                     LGWFSVISLTYLNLRGLPGQIESFFGEQATSAQLALADHIAYVIIVLVLLLLAWTIGD
                     LYKGNKKYEQRLQEMVEEIE"
     gene            10109..10333
                     /locus_tag="LLC22_001644"
     CDS             10109..10333
                     /locus_tag="LLC22_001644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YneF family protein"
                     /protein_id="HBK5434926.1"
                     /translation="MLSTGIVVLIAIIALLIGAVGGFFLARKYMKDYLEKNPPVNEDM
                     LRSMMMSMGQKPSEKKIRQMMQQMKNQGKK"
     gene            10474..12225
                     /locus_tag="LLC22_001645"
     CDS             10474..12225
                     /locus_tag="LLC22_001645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5434927.1"
                     /translation="MSIFRKLGWFFRQEKKHYLIGVFSLFAVALVQLVPPKVIGIIID
                     EIADKNLSVKIIFGWIFLLIIAAFLQYLFRYIWRTNIWGSAARLEKELRQQLFKHFTE
                     MDNLFYQKYRTGDLMAHATNDLNAIQNVAGAGILTFADSVITGGTTIIAMILFIDWRL
                     TLIALIPLPLLAVTSRVLGSKLHDAFRDSQEAFSSINDKTQESITGIKVIKTFGQEKE
                     DLADFEEKIEDAIIKNKRVNFLDSLFDPFITLIIGLSYVATIILGGKYVLEGTISIGQ
                     MVSFISYIGMLVWPMFAIGRLFNVLERGNASYDRVNELLHEKTHIVEQLGAVQTPAKG
                     ELNVAISSFNYPKEESPALEQIKFAIQEGETLGIVGKTGAGKTTIIKLLMREYDDYQG
                     KIQFGGRSIKEYSLNALLGSIGYVPQDHFLFSMTIRDNIRFSNPKLSEEEVEHAASLA
                     FINNEIKELPKGYDTLVGERGVSLSGGQKQRISIARALIKNPELLILDDALSAVDAKT
                     EEAILHNLKEIRKEKTTIISAHRLSSVMHAKEIIVVDQGKIIERGTHHELLALGGWYE
                     QMWEKQQLEAKIEGGEA"
     gene            12225..14009
                     /locus_tag="LLC22_001646"
     CDS             12225..14009
                     /locus_tag="LLC22_001646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338974.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434928.1"
                     /translation="MDENYQSEWTKSIPLKEQKKIIKRLMKFAKPFRRTFIVAILFAF
                     ALSVINVLLPRIIQTFMDDHLAKQSATTQVILFFAGMYLFGVIVKSIIWFFQWYLYSM
                     ASLKTYQYIRVKLFEKLHTLGMRYFDQTPAGSTVSRVTNDTETLFEFWYVFLMVLTGI
                     FAVVSSFIAMFQINGEIALWTLVFLPILGIVIWYYQKFSSRIYRNMREKLSQLNTKLN
                     ESISGMRIIQQFRQEARLAKEFEQVNNEYLDTRYAMIKTNSILLSPIINFLYALAIAL
                     VLTLFGIDALHSPVEVGLIYAFTTYVQGFFNPMSQMMDFLSIFTDGMVAGSRILKIMD
                     TEEYAPQQNPGADQMITSGKIEFRNVSFSYDGEHNVLNNISFVANPGETVALVGHTGS
                     GKSSIINVLMRFYEFYEGQILIDDHDIREYPMEELRKKMGLVLQDAFLFYGDIAGNIR
                     MMNPAITDEQIRHAAEFVQANKFIDELPKGYHSKVIEHGASYSSGQRQLITFARTIVT
                     DPKILVLDEATANIDTETEGLIQEGLAKMRQGRTTIAIAHRLSTIRDAELILVLDKGH
                     IVERGNHETLLAQNGLYADMYKLQSSGI"
     gene            14335..15186
                     /locus_tag="LLC22_001647"
     CDS             14335..15186
                     /locus_tag="LLC22_001647"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289170.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5434929.1"
                     /translation="MLIEKVLNNNVVITRDERDREMIVMGKGLAFKKKVGDPILDSCI
                     DKKFQLTNDGLSQQFQELAQAIPLEYLEISCEIIEYTKEALQVHLNDSVYISLTDHLY
                     TAIERQKMGIFVPNVLLYDIKQLFPKEYAIGKKTVKKISDKYHIKLSEDEAGFIALHL
                     VNAQGIQSQQDNTYLFTTTIQDILNIVRYYYKITFDEDSVHFFRFVTHLRFFLTRVLD
                     GAKSEDGEVSEELFQVVQKKYKDTFGCVEKIADFLTGAFDYQMSTDEKMYLTIHTARL
                     VHENRCK"
     gene            15283..17163
                     /locus_tag="LLC22_001648"
     CDS             15283..17163
                     /locus_tag="LLC22_001648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336802.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5434930.1"
                     /translation="MGKYQELAENIVKNIGGKENIRSLTHCVTRLRFKLKEENKAKDD
                     VLKKMEGIVTIMKSGGQYQVVIGNHVPDVYAEVLTVAGISDEVEEEVSSSSNLFNRLI
                     DILSGCFQPFLGALAAAGMVKGLNALFLFLKFYTEGSGTYIMLNGIGDAIFYFMPVIL
                     GYTAAKKFHLNPMVGLVIGAALCYPTVQGAALQSGFPDGSPAPYSLLGLPAYETFLGI
                     PWVGSSYTSSVVPVIFIIAFAGQVQKIAKKWIPAVVQTFLVPFSVLLIALPAGFLIIG
                     PIVSILTDLLSTGFQALMDFSPAVYGAVLGFLWQVLVIFGLHWSIIPLAIMQLAQNGW
                     SQMLVGVYGASFAQTAVVLAMYFKFKDQKMKALCMPAVISGIFGVTEPAIYGITLPKK
                     KPFIYSMIGGAISGIYLMASGTISYTMGGLGIFGVVNYITETDASGMFQAFIGIAIAS
                     VIGFSLTFFFWKDEAGETDAIQKKSGKEIVKTPIQGQIAPLNAAKDAAFAQGTLGRGI
                     LIYPEKGEVRAPFDGTVMTLFPTKHAIGMVSETGLELLIHVGLDTVQLEGKYFESLVQ
                     QGERVKQGDLLLRFDKKKIEKEGYSLETPVIVTNYTDYLDILENQGETVGPDDALITA
                     LT"
     gene            complement(17203..18105)
                     /locus_tag="LLC22_001649"
     CDS             complement(17203..18105)
                     /locus_tag="LLC22_001649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5434931.1"
                     /translation="MLLREKIKEISFSPSENEVIQFLLSDSPALGEMTIQEIAERCYV
                     HPSTLIRVAKKMGFDGWVSFRNAFLAETAYLEGNFQDVDANLPFSTTDGIMTIANKMA
                     SLEQMTIQDTLSLIHHDQLQKAKYLLLQAKKIVIFASNSNTLISQDFMLKMKRIKMDV
                     TIVTTFGESFYEAYNCTSDMCGILISYTGENKVILRTAEILKQNHVPILALTSIGDST
                     LSAMSTAALRLTTRERLYSKIGNFTINTSICYLLDVLYSCVFAENYQQNLVHLISVGQ
                     KFDKRPISSAIMKEPFNFENKEVE"
     gene            18336..19739
                     /locus_tag="LLC22_001650"
     CDS             18336..19739
                     /locus_tag="LLC22_001650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK5434932.1"
                     /translation="MAKGIKIATIGGGSSYTPELMEGFIKRYEELPIREIWLVDVEEG
                     KEKLEIVSQMSQRMWDASPYEVKIYATLDREEALNDADFVTTQFRVGQLDARIKDERI
                     PSYYGMIGQETNGAGGIFKAFRTVPVVLAIVEDMKRLCPNAWLINFANPSGMVTEAVI
                     RYGKWDKVIGLCNVPVMAMMTEPAMLGKKKEELIYKFAGLNHFHWHKVADNKGNDRTA
                     ELIDRLYDEDNGLPKNIFDIPFFKEQLKQMNMIPCGYHRYYYREEEMLEHALEEYQTI
                     GTRAQQVKETEAELFELYKDPELDHKPEQLQKRGGAYYSDAACETIASIYGNKETQIV
                     VSTKNDGAVPDLPADCVVEVTAYVGAQGARNVAFGSLPAAERGWLQVMKNMELLTIEA
                     AVTGDYGTALQAFTINPLIRSGKTAKRIMDELFIAHQQYLPQFKETISRLKEEGIEVQ
                     DELARELSGNTHIMEEV"
     gene            19739..21172
                     /locus_tag="LLC22_001651"
     CDS             19739..21172
                     /locus_tag="LLC22_001651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-glucosidase"
                     /protein_id="HBK5434933.1"
                     /translation="MGFRKDFLWGGATAANQCEGGYDEGGRGLANVDVVPIGKDRFPV
                     ITGKKKMFEFDEDHFYPAKIAIDMYHRYKEDIALFAEMGFKTYRMSIAWSRIFPMGDE
                     KEPNEAGLKFYEDVFKECQKHGIEPLVTITHFDCPMHLIKEYGAWRSRELVGFYENLC
                     RVIFNRYKGLVKYWLTFNEINMILHAPFMGAGLYFEEGENEEQVKYQAAHHELVASAI
                     ATKIAHEVDPENKVGCMLAAGAYYPYTCNPEDVWASRKSDRENYFFIDVQSRGEYPAY
                     ALKEMERNGIQIEMEPGDAALLKEHTVDFISFSYYSSRVSTTDNELLEQTAGNIFASV
                     KNPYLQASEWGWQIDPLGLRITMNDIYDRYQKPLFIVENGLGAVDTPDENGYVEDDYR
                     IDYLAAHIQAMKDAVELDGVDLLGYTTWGCIDLVSAGTGEMKKRYGFIYVDRDNQGNG
                     TLARSKKKSFNWYKKVIDSNGENLSND"
     gene            21317..22243
                     /gene="trxB"
                     /locus_tag="LLC22_001652"
     CDS             21317..22243
                     /gene="trxB"
                     /locus_tag="LLC22_001652"
                     /EC_number="1.8.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin-disulfide reductase"
                     /protein_id="HBK5434934.1"
                     /translation="MYDVIVIGAGPAGMTAALYASRSNLSVLMIEQGAPGGQMNNTAE
                     IENYPGFDSIMGPDLAYKMYESVSRFGTENAYGIVQDIKDHGSHKEVICEDKSYEGKT
                     VIIATGCIHRKLGVPGEEEFAGRGVSYCAVCDGAFFRNKRLVVIGGGDSAVEEAIYLT
                     QFASEVVIVHRRDELRAQKIIQDRAFANEKISFMWDTVVDEIVGNEMVVTGVKARNVK
                     TGNEFDLAADGVFIYVGLDPLTAPFREAGLTNEAGWIPTDNEMKTNMPGVFAIGDVRE
                     KDLRQITTAVGDGGIAGQQVYKYLESLEETTA"
     gene            22457..24184
                     /locus_tag="LLC22_001653"
     CDS             22457..24184
                     /locus_tag="LLC22_001653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880351.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBK5434935.1"
                     /translation="MSWEQVYEQWVHEENLEENLKKQLNDLGEDPEKLEDAFYAPLEF
                     GTAGMRGILGPGINRMNIYTVRQATEGLARFMDTQGEEAKRRGVAIAYDSRHQSPEFA
                     MEAAKTLAHHNIPSYVFESLRPTPELSFAVRHLKTFAGIMVTASHNPAAYNGYKVYGE
                     DGGQMPPADADALTKYVREVSNPLKVEVLSDEEAKHSGLITIIGEEVDAAYLEEIKAV
                     TIDRELVETMGKDLKLVYTPLHGTGKMLGERALKQAGFEQFVLVPEQAVADPDFTTVK
                     SPNPEEHSAFEYAIRLGEKEGADLLIATDPDADRLGAAVRLPDGSYEVLTGNQIGALF
                     AQYILEAHQSRGTLPENAAVLKSIVSSELPTAIAEHYGATMFNVLTGFKFIAEKIQQF
                     EEDHSHTFMFGFEESYGYLVKPFVRDKDAIQALLLLAEVAAYYKKQGKTLYDGLQTIF
                     ETYGYFAEKTISVTMSGQEGSAKISALMEKFRKEAPTEFAGAKVIQTEDFKELTRTDR
                     EGNVEKLTTPPSDVLKYTLEENGWIAIRPSGTEPKIKFYIGVKGSSTEDAAEKVASYE
                     AIIKKMTEE"
     gene            24199..24549
                     /locus_tag="LLC22_001654"
     CDS             24199..24549
                     /locus_tag="LLC22_001654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK5434936.1"
                     /translation="MEKVVNFRSQSFFKLEVNGLPDTQKSKVEKVSQLFKMLSDPTRL
                     KILLYLKDGEQNVTAITQAVEMEQSAVSHQLRLLRENHVVKSHREGKAILYSLDDSHV
                     LDILNQTLKHVEHQ"
     gene            complement(24641..25501)
                     /locus_tag="LLC22_001655"
     CDS             complement(24641..25501)
                     /locus_tag="LLC22_001655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase/pyrophosphorylase"
                     /protein_id="HBK5434937.1"
                     /translation="MSSDSTEIVTFFVISDSAGETATKLAQATMAQYPTVEFNLFRRT
                     FVTDEKTLKQALQDALEEKALVLHTLINQELIEITRSFCEEHQLFSFDVMTPPISEIE
                     RLTGIKPIRQPGALHLLNENYFKRIKAMEFAVKYDDGKDPRGFLEADVVLLGVSRTSK
                     TPLSLFLANKNLKVANLPLIPQAHIPKQLWEIDPKKIVGLTNNPDILNNIRKERMRSY
                     GLNPDTAYSDIEKIRAELDFANDLYEKLGCVVINVASLSIEETASLILNALDLEDHSY
                     YGTETTEKSD"
     gene            25593..26021
                     /locus_tag="LLC22_001656"
     CDS             25593..26021
                     /locus_tag="LLC22_001656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional repressor"
                     /protein_id="HBK5434938.1"
                     /translation="MKKQTLIEQSLETLKNNGFKYTKKREALLTYLVKRNRYVSAKEV
                     FDYMNQEFKGVSYDTIYRNLHDFAEIDLLEETDLNGEMKFRFHCCQGEIGHHHHFICT
                     VCGTTKEIHMCPMNYFEEQLGGCTIEGHRFEIFGRCENCQ"
     gene            26183..26359
                     /locus_tag="LLC22_001657"
     CDS             26183..26359
                     /locus_tag="LLC22_001657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010754017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S21"
                     /protein_id="HBK5434939.1"
                     /translation="MSKTVVRKNESLDDALRRFKRSVSKAGTLQESRKREFYEKPSVR
                     RKKKSEAARKRKKF"
     gene            26386..26832
                     /locus_tag="LLC22_001658"
     CDS             26386..26832
                     /locus_tag="LLC22_001658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GatB/YqeY domain-containing protein"
                     /protein_id="HBK5434940.1"
                     /translation="MSLLSRLNDDMKAAMKAKDKESLQVIRMIKSSIQNEQIKEGHDL
                     TEEEELTVLSREMKQRRDSLHEFEEAGRDDLAEKVKSEIVIVEKYMPEQLSDEEIRQL
                     VQEAITQTGASSMKEFGKVMGAIMPKVKGKADGNQVNAIVKELLQS"
BASE COUNT         8512 a         4797 c         5747 g         7844 t
ORIGIN      
        1 aaaggtggga gcggactagc tctcaccttt tttactctta tttttctaaa acaagtaatt
       61 cttttggtgt agtcgtgaat ggcacacagc catcgcttgt cacatataca cagtcttcga
      121 tacgtacccc tactttttca ggaatataga ttcctggttc aagagagaag cacatccctt
      181 cttcgattac taagtcattt ccttctacaa gggaagggaa ttcgtggacg gttgttccga
      241 tcccgtgacc taaacggtga ttgaaatatt cgccgtagcc atagctgttg atcacgtttc
      301 gtgcgatttg atcaagttca cctgctgtca cacctggacg gacggcttct tgtgcggcaa
      361 gctgtgcttc aagagtgatg ttgtagattt tttcttggaa gtcggttggt ttttgataag
      421 caattgtacg agtagcatca ctgcaatagc cattccaaac aacgccaaga tcgaataaca
      481 caagttcatt cggtgaaatc ttcgtatttc ctggtgtacc atgagggctt gcagcatttg
      541 ctcctgcaag gactaatgtg tcgaaagaca tttgtgaaac accttgtttt ttcaattggt
      601 attcaatttc tgcaatgatc gcttgttcag tcacgccttc tttcactgct ttaaagccaa
      661 tctcaaatgc aacatcggcc catttaccag cttcgatcag tttgtctttt tcctctagag
      721 ttttgatcag ttgtagacgt tggatgatgg aagttagatc agtgtaagaa tccgttcccg
      781 tcaagatatc agagatagca tcgaagcgct cgacagtcaa ggcgttcttt tcaatcccta
      841 cattgccagg ctgaccatag cgagtacgaa gttcttttcc gatgatctcc caagggtttt
      901 cgctgtctaa atagccgcgg acatcatacg cccaactact gttttgagca tcttcaactt
      961 ccaaagcagg agtgaaaagg aaaggatctt gttcaagagg gataaaaaga gctagtacac
     1021 gctcatgagg atcactttcg tatccggaaa agtaagcgat gtggccaggg tcgctgatat
     1081 aagccaattc gacttggtgt tgtgccatcc attgacgtag ttcattgatt tttacgttat
     1141 tcatttggca acctactttc taaattaatt ttgtattcaa taattgtacc actgatttat
     1201 taaaagacca acgttctaaa aactgaaaaa agtaaaaatt ttcatgaaaa cagagataaa
     1261 acggttgcaa ttcttgagat tatttgatat tctattttag aaatgtaaga cgtattttca
     1321 gaaaacatat aaaatatgaa tgggagaaca caaatggaaa agcaaacaat cactatctat
     1381 gatgtagcga gagaggcaaa tgtttcgatg gctactgttt cacgtgtcgt aaatggcaat
     1441 ccaaacgtta aaccagcaac aagaaaaaaa gtcttggaag tcatcgatcg cttggattat
     1501 cgtccaaacg cagttgcgcg tggcttggca agtaagaaaa caacaacagt tggggtaatc
     1561 atccctgatg tcagcaatat gttctttgct tctttagcac gtggtatcga tgatgtggca
     1621 acaatgtaca aatacaatat tatcttagca aattcagatg gcaacgacca aaaagaagtc
     1681 aatgtattga ataacttact ggctaagcaa gtggacggcg tgatcttcat gggtcaccat
     1741 atcacagacg aaatccgtgg agaattttca cgttcaaaaa ctcctgttgt attagctggc
     1801 tctattgatc cagatgaaca agtaggtagc gtaaacattg attatgtatc cgcaacaaaa
     1861 gatgcagtaa ataaattggc aaaaagcggc aataaaaaaa tcgcttttgt cagtggtgcg
     1921 ttgatcgatc ctatcaatgg acaaaatcgt ctgaaaggct ataaagaagc attaagcgaa
     1981 aataacctac catatagcga aggattgatc tttgaagcac aatacaactt caaagatggt
     2041 ctatctctag ccgatcggat ccataatagc ggtgcaacag ctgtctatgt ttcagatgat
     2101 gaattagcca tcggtatttt ggatggttta ttagatcgtg gcgtgaaagt accggaagga
     2161 ttcgaaatca tcacaagtaa caattcacta ctgacagaag tagctcgtcc tcgtttaaca
     2221 agtatcacac aaccattata cgatttaggg gcggtatcta tgcgcctatt gacgaaaatg
     2281 atgaataaag aagaagtcga agaaaaaacg attatcttgc cttatggaat cgaagaaaaa
     2341 ggatctacaa aataataaaa ggacaaccat tcagaggttg tgagcctgcc gtttaactct
     2401 gcgttacaag gagcaatttc aaaaaacagc atttcatgtt tgatgaatat tgtgactcgt
     2461 gattcggagt tggcaggaga acaccgttta ttcgggaaaa ggggttatga caaaattttg
     2521 ttataatcct ttttttgtgt cttaaaaaag agagaaagtg gttgaaatta catttatcgt
     2581 atataaaaca atccgtgtat agatgctgca ttttgttcac caccatcaaa aaaataaggg
     2641 actgtgacaa tactattgtc acaatctctt attactgtgt attctattaa atcaatcatc
     2701 tttctcatct gattctttgg ttgcttgatt cgctcttgca taagctgaag cggtgttcca
     2761 gtaatctgta tagttttcat cggtaccgcc aacgccaaat ttaaaggcgc ttttcttcgg
     2821 tccatttttc gcccatagcg attcaactgt ttttccaggt gtttggatgg attttttatt
     2881 gacagtaact tttccaggtg tttgaccagt aaatccagat acttttttct tcatcacatc
     2941 agatgataat tcgaatttct catcagtgcc aaaaatgtca ggttttgctt ggtaagcttg
     3001 attgatcaga ttggcaagat aattagccga acgtatcctt gctttgctgt ccattccagt
     3061 attgtcatcg tgccctgccc agctactgat ggtaatagac ggagtagaga caattagcca
     3121 tgaatctcgg tattcattgg tagaaccagt ttttccgacc caatctgctt ttcctagatt
     3181 tccgtttaag cttgagatgg catctttgaa tggtgtagtg atttttgcat tgatcacact
     3241 gcgcatcatg tcattcatga tcgatgccgt tgcttccgaa tagatccgga cagagttgct
     3301 ttcgtgttta taaattacat ttcctgcgtt atctgtgatg gaatcgatga tatagccttc
     3361 ttcatagacg ccgccgtttg ctaaagcctg aaatccattg gtctgttgaa gcgtcgtgac
     3421 atctactgta cctaaaggag cagattcaac gccccaattg tcatttgccg ggtagttcat
     3481 ctttgccaag tagtgctcgt aagcatattg tttcgatcca ccggaattca acacatcttg
     3541 atataagtga taagccggga tattgttgga ccattctagt gactcacgga cggtttggaa
     3601 ggtgttcgat ccttcgttag tagcattgac gattttctcg ccagcatttt ctccttcttg
     3661 ccaagttgtt gcataatctg atacacggga ttctgatccg ataagcccca tgtcgattgc
     3721 aggtccataa acaagaactg gtttgattga tgagccagct tgacgttctg tatcgaaggc
     3781 atggttattt tgattctgac tgtaattccg tccgccaacg aatccgtaga tgcggccagt
     3841 tctgttatcc atcaatacat ttccggtttc tacttgactg ccagcaccat catctaacat
     3901 gtatccataa ttttctacgc cattttgcaa tgcagcatag acatctttat cgattgtcga
     3961 atggattgta tatcctttat tttggattgt ttgctgtgcc ttttgataat aagcgtcact
     4021 gaccgatgaa tcagacatat cagcgttgtc tttttcagcc aattgttgtg caatgattct
     4081 tgttgcttca ttcatcacag tataatacaa gaattctctg tcagtctgtt ctgcgatttg
     4141 ttgtggtaga aagtcttttg taaggtcata ggcttttgct tcttcgtatt gttctttcgt
     4201 aatttggcct tcacgataca tactgaataa aacaaaatct tttctggcaa ggccggcaga
     4261 aagatcttct tttagcgcac ctgtgttcgt gtatggacta tacgtgatcg ggctttgggg
     4321 taatccagcg atataagcag cttgcggcag cgtcacatct tttgcatcta caccaaagat
     4381 tcctcttgca gcttcctgga ctccagcaat gttttgtccc ttattattac gaccaaatgg
     4441 tgagacattc aaatacgtag caatgatctc atcttttgaa aagtattttt ctacttgtgc
     4501 agaaagaatg atctcgtttg ctttacgttt gaatgttgtt tcatctgtaa ggatctgctg
     4561 tttgactaat tgctgtgtca aagttgatcc accagaagag ccaataccag tagcttcaga
     4621 tactaacgct cgtaaaacag ctttaggaac gtaaccttgg tgtttatcga agtattcatc
     4681 ctctgtgctg ataattgcag ttttcaataa aggtgaaatt ttatcagatg aaatagtcgt
     4741 gcgcatcaga tctgtctgga tttttgatat ctctgtatta tctgcataaa caatctttga
     4801 cgtttctgta atgtttccta gttctgtctg cagtgctttt ttagtcggca attgtgtgtc
     4861 ttcgacgaga taggcaaaat agccagcgcc tattccaata cctagagctg cgaacatcaa
     4921 aagaagaaca gtaataaaaa cagtcaatga ttgaaaaact ctaaaaataa tcttaggaac
     4981 aaaccatttt tctttttttc ttctattctg tttttttcga gtatttttgc gtggcaaaag
     5041 ggtcacctca actaatggtt ttatttcgct aattatagca aataatagaa caaaaaaaca
     5101 gacaaggctg tttttggcag gaatttcttt tttaaaggag ttaaaacgtg agaaaatgat
     5161 cttttttata aaagagttct taagcttttc tttagagaaa atttcagtta ctatggagaa
     5221 cagggcaaag aaaaatcaat cattttcttt gtatatcatc ttaccaatat ataggaattg
     5281 ttagtaacaa ttgcctttca aggaggaatc catccatgtt attaggctca cacgtcagca
     5341 tgagcggaaa gaaaatgctg ttaggagcag cagaagaagc agccagttat ggatcttcga
     5401 cttttatgat ctatacaggc gcccctcaaa acactagaag aaaagccatc gaagagatga
     5461 atattgatgc cggaaaagcg tacatggcag aaaacggtct aacaaatatc gtcgttcatg
     5521 ccccttatat cattaatttg gggaatacga tcaaaccaga aatgtttcct tttgccgtcc
     5581 aatttctgag agaagagatt gttcgtgcgg aagctttagg cgctactcaa attacacttc
     5641 acccaggtgc tcatgtaggg gcaggaacag aagccggaat tgctagaatt attgaaggct
     5701 tgaatgaagt tttgacaaaa gaacagacgg cacaaatcgc tttggagaca atggcaggta
     5761 aaggtacgga aatcggtcga acatttgagg aattagcgca aatcatcgat ggagtaaaat
     5821 tgaatgaaaa attatccgtt acttttgaca cctgtcatac gaatgatgcc ggttataata
     5881 ttaaagaaga cttttcaggt gtaatggaag agtttgataa gatcatcggg ttagatcggc
     5941 ttaaagtact ccatatcaat gattctaaaa atccgcaagg ttcgcataaa gaccgacacg
     6001 ccaatattgg ttttggaaca atcggattcg acacgctgaa taagatcgtc catgatccaa
     6061 tgtttgacaa tatttcgaaa atcttggaaa ctccctatgt cggcaaagat aaaaagaaag
     6121 cttacgcacc atatggaaaa gaaatcgcca tgttcaaagc acaaatattc gatccagaag
     6181 tgtttcctga gttattagca gaagaagtga tactctaaga ttttctatct gacagcagca
     6241 aaaaaggacc aggcacattg ccttgtcctt ttttgtttaa gaaacaaagg agtgcttttt
     6301 gcagtctttt tcatcatgca tcttctcccc cctcttttta aatttagaca aacagggtat
     6361 actggtagaa aagtaaaaaa acgaaaagtt tcacaagcaa gtggcaaaac gtgattggaa
     6421 ggacgaaaag atgctgaaca ctttaaaacc cttgatcaac caactaaaaa agaaacatac
     6481 atactttatt cttggcatag ccctattatt tacaattatt cgtttgtatt tatatagtaa
     6541 agcaatctat ggaacagaca tgtcggcaac ctatgatgac cagctgctga ttcgctatgc
     6601 tcaaaatatt ttggacggta aatggctagg ggagtatacg actacaacac tttccaaagg
     6661 aatctcctac agcttatttt tagtacttgc acataaactg catctttctt atgcagtttt
     6721 gttcggcatg ttcagtattt ttgccagtat attggttgca ctcgcgttta aaccgatcgt
     6781 gaagaacaag tatcttcttt taagtttcta tttttatttt ttgttttctc cgattagttt
     6841 tacacatgaa tattccactc gaacgtatcg taatgccctc gtgattccgg ctgttgagat
     6901 cattatcgct tgtttactag ctatttatta ccgcaaatac ggttctagca gaaaattgct
     6961 gccatggttt ttagggcttt ctgtcgcttt tcctttcttt tggttcattc gcgaagattc
     7021 tatctggctt cttcctttta ctgtagtagc tttgggtatc agtttcgtcc agatcttgct
     7081 agggcaagac ttttctttca aagaagtaaa gaagttaaaa aaacgactct ttcttctctc
     7141 gaaacgggaa tggctgaaac tttcattgtt tttacttcct atagttggct tttccatcgt
     7201 ctatcagtgg atcgaatata aaaatgagac aacatacggt attgcaacca tcaatgaccg
     7261 ttccagtgga gaatttggac gtttgatgaa acaactgatc cgaatagatg atgaaacgaa
     7321 cttgaataaa gaaaacagtg agatatgggt ctcacatgct gcactaaata aagcattagc
     7381 cgcatctcct acattccata ctgtttctac ccgtattgac gaattatata cgactcacgc
     7441 gtggactcaa ggtggaaaag taaaagaatt acccggagat atcatctttt gggcattgcg
     7501 agatgtggta agcgaatctg gttattacca aaacaatgca aaagaaacca atgatttttg
     7561 gaaaaaagtc aaccaagaat tagaagaagc ctatcacaag ggaaccatca aaaagaaaaa
     7621 agagttctat ctgatgggat caggagatgg aaagacgatg agtgatctac caatcgtatt
     7681 cgatttcctt caatcaggat acgcttatgc atggcgatat aaagatttcc atcaaggagg
     7741 aaattatagt ttcggaacgc aagaacaagt caaacaggct caagaattat taaaccttcc
     7801 gctaatggag aattggatcg atagtaatga accgagaaca cctaatttcc aattaacaaa
     7861 atcagcaaaa gtcgcgaatg tcatcataaa aatttaccaa gttctggcta ttcccgtgct
     7921 gattgcttca atagcaggga tattacttat gatactagga accgtatttg caaaagctga
     7981 tcgtgcctat tatagttcct ctttgattgt ggtcaccgga ttaatactga cacaattggt
     8041 ttttcttttc ggtgtctcgt ggttttgttc ttatgcgcca gaaaaaaagg attatttttt
     8101 aagtgtctac actggcgcag gcgtgccgtt aacgcaattc atcgtagtaa caagcatgct
     8161 agttttcagt aaattaaatc tgaaaaaagc tttatcttct aaataaaaag acccttggta
     8221 gctagatttt taacctaact atcaagggtc tttgtgtgga aaaatcagtt tttattcgat
     8281 ttcttctacc atttcctgca aacgctgttc atattttttg tttcctttat ataaatcacc
     8341 aatcgtccat gccaacagga ggaggacaag aacaatgatt acataagcga tgtgatcagc
     8401 caatgctagt tgagcggaag tggcttgctc gccgaagaaa ctttcgatct gtcctggtaa
     8461 tcctcgtaag ttcaagtaag ttagactaat cacagagaac cagccaagaa gttttacgat
     8521 gaatgaattt ttaaatcggc tacccatctc cgcttggctg ttggtcatca tcagtaaagg
     8581 gatcatcgaa aacggcaacg caaaagccaa gaacacctgg gattcattca ttaagttatt
     8641 caaagcggta tgttcttcga tcgttccttt tgtacttgta aacaaaacac aaatcaatac
     8701 aggaatcaca gaaagcaatc gtgtgaccag tcttcttagc caaatcggga tacgcatatg
     8761 gatgaatcct tccatgatga cttgaccggt caacgtacca gtaatagtag agttctggcc
     8821 agaagcaaga agtgctacag caaataaagt ggacaagata ccagattttg ctacagcaat
     8881 caagatacca ttgctcatag ctgatggatc agataaagct tcatacagac caaaaaagga
     8941 aggatcttga acagaaccgg ttttgaagac agcgacaccc ataatcaata gcagcgcatt
     9001 gactagaaaa gccatcgaca attggatatt agagtcccaa gtagaaaaac gtacagcttg
     9061 tgctacatct tcttcgtctt ggtgatcgat cttccgagtt tgtgaaactg ctgaatgtag
     9121 atataagtta tgtggcatga ctgttgcgcc aataatccct aatgctccag ttagcggagt
     9181 ttcgccacca atgacaggtg agtcggagaa tgtatggctg ttagggataa agccagcaaa
     9241 taaactgtgc caatctgggt tagacaagcc aacttgatag acaaaaacga ataaaatgac
     9301 gaaaatcaag cagacaacca gtgcttcgat cttacgaaac ccgacttttg tcagtagtaa
     9361 gagaacgaaa acatctaata cagtaataaa gacggcaatc accaatggaa tatcaaaaag
     9421 taagtagagg gcgattgctg caccaatgac ttctgcaata tctgttgcca taatggctaa
     9481 ttcagtcaag atccataaaa tgacacccaa tgtcttactt gtgcgtgctc ggattgcttg
     9541 ggccaaatcc atttgggtca cgattcctaa ttttgctgcc atatactgta aaagcatagc
     9601 aatcagacta gacatcaaaa taactgacat caataaatat tggaaatttt gtcctccggt
     9661 gatcgaagta gaccagttac ccgggtccat atacccaact gctactaacg caccaggtcc
     9721 agagtaagca agaagtgttt taaaaaaact tttccccttt ggtacatcca ctgttccatt
     9781 tacttcagct aaagataaac catttgtatg ttcaataagt cgatgcttat gaaattgttt
     9841 gttggattga ttattcaaga aaaaaccacc tttcctattt atctacgatt acattctaca
     9901 cctcaaaaag aaaaaattaa agaaaaagat tcggtatgcc taattttttt tcgtggcgtg
     9961 tcttgctaga tgacgaaaga aattttgttc tcctctaaaa aaaccactat tttttgcatg
    10021 aaactaaaga atacgccttt cttttttcaa taaactttag taaaataagt cattgagagc
    10081 aattcggaaa tagaaaggag agatttatat gttatcaaca ggtattgtcg tacttattgc
    10141 tattattgct ttgctaatcg gcgcagtagg tggctttttc ctagcgcgta aatatatgaa
    10201 agactattta gaaaaaaatc ctcccgttaa tgaggacatg ttgcgatcaa tgatgatgtc
    10261 aatggggcaa aaaccatctg agaagaaaat tcgccagatg atgcagcaaa tgaagaacca
    10321 agggaaaaaa taggttctga cccaacgact ttttacgggc tgattttttc agtccgtttt
    10381 ttatttcgta atttgttaga ctattcagat tattcagcaa aaagacaagc acagacaatc
    10441 ctaggctctt gataaagaca aaggaggagt aaaatgtcga tttttagaaa gttaggctgg
    10501 ttttttcgtc aggaaaagaa acattattta attggggttt tctcgctatt cgcagtggcc
    10561 ttggtacagt tagttcctcc aaaagtgatt gggatcatca ttgatgagat tgccgataaa
    10621 aatttatcag taaagatcat tttcgggtgg atcttcctat tgattatcgc tgctttttta
    10681 caatatcttt ttcgttatat ctggcggacg aatatttggg gaagtgcagc tcggttggag
    10741 aaagaacttc ggcagcagtt attcaaacat tttacagaaa tggacaatct cttttaccaa
    10801 aaatatcgga ctggggattt gatggctcat gcaacgaatg atttgaatgc gatccagaat
    10861 gtagcaggag ctggtatctt gacctttgca gattcagtga ttacgggcgg aacaacgatc
    10921 attgcgatga ttttgtttat tgattggcgc ttaacactga ttgcgctgat tcctctgcct
    10981 ttgctggccg tcacttcacg agtgctgggg tcgaaactcc atgatgcttt tcgtgattcg
    11041 caagaagctt tttctagtat caatgataag acacaagaaa gtatcactgg gatcaaagtc
    11101 attaaaacat ttggacaaga aaaagaagat ctagcggatt ttgaagaaaa gattgaagat
    11161 gcaattatta aaaacaaacg agtcaatttt ttagactcct tatttgatcc attcattacc
    11221 ttgattatcg gtctgtctta tgttgcaaca attattttag gtggaaagta tgtcttggaa
    11281 ggcacgatct cgatcgggca gatggtctca tttattagtt atatcggtat gcttgtttgg
    11341 ccgatgtttg cgattggtcg attgttcaac gtattggaaa gaggaaatgc ttcttatgat
    11401 cgcgtcaatg aacttttgca tgaaaaaacg catatcgtgg aacaactggg tgcagtgcag
    11461 accccggcaa aaggcgagct gaatgtagct atttcctctt ttaattatcc gaaagaagaa
    11521 tcaccagcat tagaacaaat caagtttgca atccaagaag gagaaacatt aggtattgtt
    11581 gggaaaactg gtgcgggaaa aacgacgatc atcaaattac tgatgcgtga atacgatgat
    11641 tatcaaggga aaatccaatt tggcggacgt tcgatcaaag aatattcatt gaatgcttta
    11701 ttaggatcaa tcggctatgt gcctcaggat cacttcttgt tttcgatgac cattcgagat
    11761 aatatccgtt tttctaatcc aaaactttca gaagaagaag tagagcatgc ggcttcttta
    11821 gcatttatca acaatgaaat caaggaatta ccaaaaggtt atgatacctt agttggagaa
    11881 cgtggagtct ctttatctgg cggacagaaa caaaggattt cgattgctcg agcattgatc
    11941 aaaaatcctg aattattaat attagatgat gcactttctg cagtagatgc caaaacagaa
    12001 gaagctatct tgcataattt aaaagaaata agaaaagaga aaacaactat catttcagct
    12061 caccgtttaa gtagcgtgat gcatgcaaaa gaaatcattg ttgtcgatca agggaaaatc
    12121 attgaacgag gaacccatca tgagctgctt gcactaggcg gctggtatga acaaatgtgg
    12181 gagaaacagc aattagaagc gaagatagaa ggaggcgagg cctgatggat gaaaattatc
    12241 aatcggaatg gacaaaatcg attccactta aagaacagaa aaagatcatc aaacgactga
    12301 tgaagttcgc caaacctttt agaagaacgt tcatcgttgc tatcttattt gcgtttgctc
    12361 tgtctgtgat caatgtccta ttgccaagga tcatccaaac ttttatggat gatcatctgg
    12421 ctaaacagtc ggctacgaca caagttattt tgttttttgc tggtatgtac ttatttggag
    12481 tcatagtaaa aagtatcatt tggtttttcc aatggtattt gtattccatg gcttcattga
    12541 agacctatca gtatattagg gtaaaattat ttgaaaagct gcatacacta ggtatgcgtt
    12601 attttgatca gacaccggca ggatcaaccg tttctcgagt gacgaatgac acagaaacgc
    12661 tatttgaatt ttggtacgtc tttttgatgg tattgactgg gatctttgca gtcgtttctt
    12721 cattcattgc catgtttcaa atcaatggag aaattgcctt gtggactttg gtgttcttgc
    12781 caattttagg aatagtcatc tggtattacc agaaatttag ttctcgtatt taccggaata
    12841 tgcgggaaaa attaagtcag ctgaatacga aattgaatga atcgatttcc ggcatgcgta
    12901 ttatccagca gtttcgccaa gaagctcgtt tagctaaaga atttgaacaa gtgaacaatg
    12961 agtatttaga cacgcgttat gcgatgatca aaacaaattc gattctgtta agtccgatca
    13021 tcaattttct atatgcattg gcgattgcgt tggtgttgac tttgtttggg atcgatgcgt
    13081 tgcattctcc cgtagaagtt ggactgatct atgcatttac gacctatgtc cagggatttt
    13141 ttaatccaat gtctcaaatg atggactttt tgagcatctt cacagatggg atggttgctg
    13201 gtagtcgtat cttgaagatt atggatacag aagaatatgc accacaacaa aaccctggag
    13261 cagatcaaat gattacttca ggtaagattg agtttcgcaa tgtaagcttt tcttatgatg
    13321 gagagcacaa tgtattaaac aatatctctt ttgttgctaa tccgggagag accgttgcat
    13381 tagtgggaca caccggaagt gggaaaagct cgatcatcaa tgtgttgatg cggttttacg
    13441 aattttatga aggtcagata ttgattgatg atcatgacat tcgagaatat ccaatggaag
    13501 agttacgtaa gaaaatgggg ctggtcttgc aagatgcttt cttgttttat ggggatatcg
    13561 caggaaatat tcggatgatg aatccagcta tcacagacga acagatacgc catgcggctg
    13621 agtttgttca agcaaacaaa ttcatcgatg aattaccaaa aggatatcac tcaaaagtga
    13681 tcgaacatgg tgccagctat tctagtggac aacgacagct gatcactttt gcgcgaacaa
    13741 tcgtgactga tcctaaaatt ctagtattgg atgaagcaac agcaaatatc gatactgaaa
    13801 cagaaggatt gatccaagaa ggattggcga aaatgcgaca aggacggaca acgattgcga
    13861 ttgcccatcg gctgtcaacg attcgagatg cagaattgat tttagtttta gacaaaggtc
    13921 atatagtaga acgcgggaat catgaaacac ttctagcgca aaatggtttg tatgcagata
    13981 tgtacaaact gcaaagcagt ggtatataaa agatgttgtg acagtagcat tttgacctaa
    14041 gcactagagt gaaaataaaa catagcttcc catatttttc atctgtgaga gttagtgtcg
    14101 tagttaccag atttaaaaaa gacgacgtca gctagtcaga agtgcctaat agcccctaag
    14161 aaagcgttga caaaatcgtt tgctttcgat aatataaaga aaacgataca acttggatag
    14221 tgattgcctg atgcaagcta aacctaatga gtctcccatg gtttcatgga cggctttttg
    14281 ggtttttctt tttgttttgg atacagccct atatatcatg gaaaggagca aaacatgctg
    14341 attgagaaag tactgaataa caacgtcgta ataacaaggg atgaaagaga tcgggaaatg
    14401 attgtgatgg gaaaaggatt ggcattcaaa aagaaggtgg gtgacccgat tcttgattca
    14461 tgcatcgaca aaaaatttca gttgacaaat gacggacttt cacaacagtt ccaagaattg
    14521 gcacaagcga ttcctcttga gtacttagaa atttcttgtg aaatcattga atatacaaaa
    14581 gaggctctgc aagtccattt aaatgattct gtgtatattt cattgacgga tcacttgtat
    14641 acagctatcg aacgtcaaaa aatggggatc tttgtgccaa atgtattgct gtatgatatc
    14701 aaacaactgt ttcctaaaga gtatgccatt gggaaaaaaa cagtgaagaa aatctcggat
    14761 aaataccaca tcaagttatc agaagacgaa gccggattta tcgcattgca tttagtcaat
    14821 gcacaaggca ttcaaagcca gcaagacaat acctacctgt ttaccacaac aatacaggat
    14881 attttaaata tcgtccgcta ttactataag attacatttg atgaagattc agtccacttt
    14941 tttcgattcg tcacacacct gcgttttttt ctgacacgtg ttctagatgg agcgaaatca
    15001 gaagatggag aagtttctga ggaattgttc caagttgttc aaaaaaaata taaggatacg
    15061 tttggttgcg ttgagaaaat agcagacttt ttaaccgggg ctttcgacta ccagatgtcc
    15121 acggatgaaa aaatgtattt aacgatccat actgcgcgtt tagtgcatga gaatcgttgt
    15181 aaataaataa aaaaggagga caaattaaca agaacgtatg aaaataaggg tagtgacatt
    15241 cagttggcta aaccttccac taattaattg gagggaatag aaatgggaaa ataccaggaa
    15301 ttagcagaaa acatcgtaaa gaatatcgga ggaaaagaaa atatccgtag cttgacacac
    15361 tgtgtgacgc gacttcgttt caaactaaag gaggaaaata aagcaaagga tgatgttttg
    15421 aaaaagatgg aagggatagt caccatcatg aaaagcggcg ggcaatatca agttgtaatc
    15481 gggaatcatg tgccagatgt ctatgcagaa gtactgacag tagccgggat ttccgatgaa
    15541 gtagaagaag aggtttcttc aagtagtaat ctgttcaatc gattaatcga catattaagt
    15601 ggctgtttcc agcctttttt aggtgcttta gctgcagcgg gaatggtcaa aggattaaat
    15661 gctttgttct tgtttctcaa attttatact gaaggatcgg gtacgtacat catgctgaat
    15721 gggatagggg atgcaatttt ttatttcatg ccagtgatct tagggtacac agcagcgaaa
    15781 aaatttcatc tgaatccgat ggtggggctc gtgattggtg cagcactttg ttatccgact
    15841 gtacaaggag cagcactaca aagtggtttc cctgatggca gtcctgcgcc ttatagcttg
    15901 ctgggtcttc cggcttatga aacatttttg ggtatcccat gggtgggcag cagttatacc
    15961 agtagcgtcg tacctgttat cttcattatc gcatttgccg gacaagtcca aaaaattgcc
    16021 aagaaatgga ttcctgcagt cgtccagacc tttttggttc ctttttctgt gttattaatc
    16081 gcacttcctg ctggcttttt gattatcggt ccgattgtca gtatactgac agatctatta
    16141 agcacgggat tccaagcatt gatggacttt tctccagctg tgtatggtgc agttctaggg
    16201 tttctttggc aagtactggt gattttcgga cttcattgga gtattatccc tcttgcgatt
    16261 atgcagctag cgcaaaatgg gtggagtcag atgttagtag gcgtttatgg cgcgagtttt
    16321 gcacagacag cagtggtatt ggcgatgtat ttcaagttca aggatcaaaa aatgaaggcg
    16381 ctttgcatgc cagctgtgat ttcaggaatc ttcggcgtaa cagaaccggc tatttatgga
    16441 atcaccttac cgaagaagaa gccatttatt tactcgatga ttggtggtgc catttcagga
    16501 atctatttga tggcatctgg aacaatcagc tacacaatgg gcggattagg gatttttggg
    16561 gtggtaaact acatcacgga aacagacgcc agtggtatgt ttcaagcgtt tatcggcatt
    16621 gctattgctt cggtaatcgg gttttcgctg acttttttct tttggaagga tgaagcaggt
    16681 gaaacagatg ctatacagaa aaaatcaggt aaagaaattg taaaaacacc gatacaagga
    16741 caaatcgctc cactaaatgc agcgaaggat gcagcttttg cacaaggaac actaggtcga
    16801 ggaatcttga tctaccctga aaaaggagaa gtacgtgccc cttttgacgg aacagtcatg
    16861 accctgttcc cgacgaaaca tgcaattgga atggtttctg aaacagggct ggaattgctg
    16921 attcatgtcg gattggatac tgtgcagttg gaagggaaat attttgaaag cttagtgcag
    16981 caaggagaaa gagtgaaaca aggcgatctg ttgctacgct tcgacaaaaa gaaaatcgaa
    17041 aaggaaggat acagtttaga aacacctgtg atcgtcacca attacacgga ttatttggat
    17101 attttggaaa accaagggga gacggtcggg ccagacgatg cacttatcac cgcactgacc
    17161 tgaacggtta ggtgaagaat ggaataggct taactattct ttttattcca cttctttatt
    17221 ttcaaaattg aaaggctctt tcatgatggc tgagctgata gggcgtttat cgaatttttg
    17281 accgacagaa attagatgga ctaaattctg ttgataattt tctgcaaaaa cacaactata
    17341 taacacgtct agaagataac aaattgatgt attgatcgta aaattaccaa tttttgaata
    17401 cagtcgctcg cgtgtcgtaa gtcgcaaagc ggctgtactc attgcagata gcgttgaatc
    17461 accgatactg gtcaaagcta aaattggaac atgattttgt ttcaatattt ctgcggtacg
    17521 aagaatcact ttattttcac ccgtataaga aatcaggatc ccgcacatat cgctcgtgca
    17581 attgtacgct tcatagaatg attcaccaaa agtggtgaca attgtgacat ccattttgat
    17641 gcgcttcatt ttcagcatga aatcttgaga aatcaaagta ttcgagttac tggcgaagat
    17701 cacgattttt tttgcctgga gcagtaaata cttggctttt tgcagttggt catgatgaat
    17761 gagagaaagt gtatcttgaa tcgtcatctg ttctaaagaa gccattttat ttgcgatcgt
    17821 cataataccg tctgtggtgg aaaaaggaag attcgcatct acgtcttgaa aattcccttc
    17881 aagataggct gtttcagcta aaaaagcatt acgaaaactg acccagccat caaaacccat
    17941 tttttttgct acacggatga gtgtagacgg gtggacatag catcgctcag cgatctcttg
    18001 gatggtcatt tcgccaagtg ctggagaatc gcttaagaga aactggatca cttcattttc
    18061 tgaaggagaa aaggagattt ctttgatttt ttcacgtaat aacatgtagt taccttcttc
    18121 ttattttttt acgtaaatta taactttttt gaaaatgttt tgtaaacgga tttatactat
    18181 ataacttaaa atagactttt tttgacaaga tatttacaaa aatccactag aaaacagtaa
    18241 cttttgtaaa tgttactgga aagaaacgga tttctattgt ttgttttgtt tacaaaaaag
    18301 ataatgaaag tgtaaaaaag taaaggagtg agaacatggc aaaaggaatc aaaatcgcta
    18361 cgattggtgg aggcagcagt tacacccctg agttgatgga aggatttatc aaaagatatg
    18421 aggaattacc gatacgagaa atctggctcg tagatgtaga agaaggaaaa gaaaagcttg
    18481 agatcgttag tcagatgtct cagcgtatgt gggatgcttc tccgtatgaa gtcaaaatct
    18541 atgcaactct ggatcgggaa gaagcattga atgatgcgga ttttgttacg actcagtttc
    18601 gtgtcggtca attagatgca cgaatcaaag acgagcggat ccctagttat tatgggatga
    18661 ttgggcaaga aacaaatggt gctggcggga tattcaaagc ttttcgtacc gttccagtgg
    18721 tcttggcaat cgttgaagac atgaagcgtt tatgtccaaa tgcttggctg atcaatttcg
    18781 cgaacccaag tgggatggtg acagaagcag ttatcagata tggcaaatgg gataaagtga
    18841 ttggattatg caatgtgcca gtaatggcga tgatgacaga accagcaatg cttggcaaga
    18901 aaaaagaaga gctgatctac aagtttgccg gtctaaatca tttccattgg cacaaagtag
    18961 cagataataa aggaaatgac cgcacggcag aattgattga tcgtttatac gatgaagaca
    19021 atggattgcc gaaaaatatc tttgatatcc cgtttttcaa agaacaatta aaacaaatga
    19081 atatgatccc ttgtggctac caccgctatt actaccgtga agaagaaatg ctggaacatg
    19141 ctttagaaga atatcaaacg attggtacaa gagcgcagca agtgaaagaa acagaagcag
    19201 agctatttga attatacaaa gatccagaat tagaccataa acctgaacaa ttgcaaaaac
    19261 gaggtggcgc ttattattca gacgctgcct gtgaaacgat tgcttcaatc tatggaaata
    19321 aagaaacaca gatcgtggta tctacaaaga atgatggagc tgttcctgac ctgccggcag
    19381 attgtgtagt agaagtcact gcctatgttg gcgcacaagg agcgagaaat gtagcgtttg
    19441 gttctcttcc tgctgctgaa agaggctggt tgcaagtaat gaagaatatg gaattgctga
    19501 cgatcgaagc agctgtgact ggtgattatg ggacagcttt acaggcgttt acgatcaatc
    19561 cgcttatacg atcaggaaag acagcaaaac ggatcatgga tgagttgttt attgcacacc
    19621 agcagtattt accgcaattc aaggaaacaa tcagccgatt aaaagaagaa ggaatcgaag
    19681 ttcaagatga actggcaaga gaattatcag gtaatacaca tataatggag gaagtataat
    19741 gggattcaga aaagattttt tatggggcgg tgctacagca gccaatcaat gtgagggcgg
    19801 ttatgatgaa ggtggacgcg gactagcaaa cgtagatgtt gtgccaatcg gaaaagaccg
    19861 ttttcctgtt atcaccggaa agaaaaaaat gtttgaattt gatgaggatc atttttatcc
    19921 agcaaaaatt gcaatcgata tgtatcatcg ttataaagaa gatattgctt tgtttgcaga
    19981 aatggggttc aagacttatc gaatgtccat cgcctggagt cgtatttttc caatggggga
    20041 tgaaaaagag ccgaatgaag ctggcttgaa attttatgag gatgtcttta aagaatgcca
    20101 aaagcacgga atcgagccac ttgtgacgat tacgcatttt gattgtccaa tgcatttgat
    20161 caaagaatac ggtgcgtggc gttccagaga actcgttggt ttttatgaaa atctgtgtcg
    20221 agtcatcttc aatcgatata aaggacttgt caaatactgg ctgacattca atgagatcaa
    20281 tatgatcctt catgcaccat tcatgggagc aggactgtac tttgaagaag gagaaaacga
    20341 agaacaagtc aaatatcaag cggcacatca tgagttggtt gcaagtgcca tcgcaacgaa
    20401 gattgctcat gaagtagatc cggagaacaa agtaggctgt atgctggcag caggagcata
    20461 ttatccatac acttgcaatc ctgaagatgt ttgggcttct agaaaatcag atcgagaaaa
    20521 ttatttcttc attgatgttc agtcacgagg agaataccca gcttatgcat tgaaagaaat
    20581 ggaacgaaat ggcattcaga tcgaaatgga accaggggat gccgcattgc tgaaagaaca
    20641 tactgttgat tttatctctt tttcttatta ttcttcccga gtttcgacta ccgacaacga
    20701 actcttggaa cagactgcag gaaatatctt tgcttctgtc aaaaatccat atctgcaagc
    20761 aagtgaatgg gggtggcaaa ttgatccatt aggcttgaga ataacgatga atgatattta
    20821 tgatcgttat caaaaaccat tatttattgt agaaaacggc ttaggtgcag tcgatacgcc
    20881 agatgagaat ggttatgtgg aagatgatta ccgaatcgat tacctggcag cgcatatcca
    20941 ggcgatgaag gatgcagtag aactagacgg agtcgatcta ttaggctata cgacttgggg
    21001 atgtattgat ttagtatcag ctggtaccgg tgagatgaag aaaagatacg gattcattta
    21061 tgtcgatcgt gataaccaag gaaatggcac attagcccgt tcaaagaaaa aatcattcaa
    21121 ctggtataaa aaagtaattg attcaaatgg agaaaatctt tcgaacgatt gatcaatgat
    21181 ttataaaagt ctattgtttt tcagcggatt tttcgagtat aataaagcta ttcgagaaac
    21241 gcaagcagaa caatagactt tttttcgcat tggctgtaaa gtatgcttac ttgattaagt
    21301 aaaggagaat ctacatatgt atgatgtaat cgttattggc gcaggtcctg ctgggatgac
    21361 tgctgcttta tatgcttcac gttcaaactt atccgtattg atgatcgaac aaggtgcccc
    21421 tggcggccaa atgaacaata cggcagaaat cgaaaattat cctggattcg attcgatcat
    21481 gggccccgat ctagcttata agatgtatga aagtgtctca agatttggga cagaaaatgc
    21541 ttatggaatc gttcaagata tcaaggatca cggcagccat aaagaagtca tctgtgaaga
    21601 taaaagttac gaaggaaaaa cagtcattat cgcaacaggc tgtatccacc gtaaattagg
    21661 cgtacctggc gaggaagaat ttgctggacg aggcgtttct tactgtgcag tctgtgatgg
    21721 tgcgtttttc cgtaacaaac gtctagtagt catcgggggt ggggactcag cagtagaaga
    21781 agccatctat ttgacacaat ttgcttctga agtagtgatc gtccaccgta gagatgaatt
    21841 acgtgcacaa aagatcatcc aagaccgtgc atttgcaaat gaaaaaattt cctttatgtg
    21901 ggatacagtc gttgacgaaa tcgttggaaa cgaaatggta gtgacaggtg tgaaagcacg
    21961 taatgtcaaa accggcaatg aatttgattt agcagcagac ggagtattca tctatgttgg
    22021 actggatcca ttaactgcac cttttagaga agcaggtttg acgaacgaag ctggctggat
    22081 tccaacagac aacgaaatga aaacgaatat gccaggcgtt tttgccatcg gagatgttcg
    22141 tgaaaaagat ttgcgacaaa tcactacagc tgttggtgac ggcggtattg ctggacaaca
    22201 agtgtataaa tacttggaat ctttagaaga aacaactgca taagtttaaa aagagtagaa
    22261 gaacgggttc aattgttctt ttactctttt ttttcgcgtg aaatttactg aatctgattt
    22321 atgcgaacac gtccaacacc ttttgataaa agaatccttt cttgatttaa gcgttttttg
    22381 gtcctcatac tttcatatct aataagtgaa tgctatactt attaagaacc atatttcaga
    22441 aagaggtgtt attttcatgt cttgggaaca agtgtatgaa caatgggtac atgaagaaaa
    22501 tttagaagaa aacttaaaaa aacaattaaa tgatctgggt gaagatcctg aaaaacttga
    22561 agatgctttt tatgcaccgt tggaattcgg tactgcaggc atgcggggaa tcttaggacc
    22621 tgggatcaat cgaatgaaca tctatacggt aagacaagca acagaaggac tagcacgttt
    22681 catggataca caaggtgaag aagcaaaacg ccgaggtgtc gctattgctt atgactcacg
    22741 ccatcagtca ccagaatttg caatggaagc agccaaaaca ctggcacatc acaatatccc
    22801 gtcttatgta ttcgaaagtc tgcgtccaac accagagctt tcttttgcag ttcgtcattt
    22861 gaagacgttt gcgggaatca tggtaactgc atctcacaac ccagcggctt acaatggata
    22921 taaagtctac ggagaagatg gcggacaaat gcctcctgca gacgcagatg cattgacgaa
    22981 atatgtccgt gaagtcagca atccgctaaa agtcgaagta ttatctgacg aagaagctaa
    23041 acatagcggg ttgatcacga tcatcggaga agaagtggac gctgcttatc tagaagaaat
    23101 caaagcagtg acgattgatc gtgaattggt agaaacaatg gggaaagatt tgaaacttgt
    23161 gtacacgcca cttcatggaa cagggaaaat gttgggcgaa cgtgcgttga aacaagctgg
    23221 attcgaacaa ttcgtactag ttcccgaaca agctgtggca gatccagatt tcactacggt
    23281 caaatcgcca aatccagaag aacattcagc ttttgaatat gctatacgac ttggagaaaa
    23341 agaaggagct gacttgctga ttgcaacaga tcctgatgca gaccgtttag gcgcagcggt
    23401 tcgtttgcca gatggttctt atgaagtatt gactgggaac caaatcgggg cattgtttgc
    23461 tcaatatatt ttggaagcac atcaatcaag aggcacttta ccagaaaacg cagcggtatt
    23521 gaaatcaatc gtttccagcg aattgcctac agcaattgcg gaacactacg gtgctaccat
    23581 gttcaatgtg ttgacagggt ttaaattcat tgctgaaaaa atccaacaat tcgaagaaga
    23641 ccattcacat acttttatgt ttggattcga agaaagttat ggttatttag ttaaaccttt
    23701 tgttcgcgat aaagacgcga tccaagcatt gcttttatta gcagaagtag cagcttacta
    23761 taaaaaacaa ggcaaaacgt tgtatgacgg cttgcaaacg atttttgaaa cctatggcta
    23821 ttttgcagaa aaaacgattt ctgtgacaat gagcggacaa gaaggttctg cgaaaatctc
    23881 tgctttgatg gaaaaattcc gtaaagaagc accgacagaa tttgccggag caaaagttat
    23941 tcaaacagaa gactttaaag aattgacgag aacagaccgt gaaggaaacg tagaaaaact
    24001 aacaacaccg ccatccgacg tattgaaata tacattggaa gaaaatggct ggattgctat
    24061 ccgcccttca ggaactgagc cgaaaatcaa gttttatatt ggtgtaaaag gaagctctac
    24121 agaagacgca gccgaaaaag tagcctctta tgaagcgatt atcaaaaaga tgacagaaga
    24181 ataaaaaact tgagactgat ggaaaaagtg gtaaacttta gaagtcagtc ttttttcaag
    24241 ttggaggtga atggattgcc agacacgcaa aaatcaaaag tagagaaagt cagtcaatta
    24301 ttcaaaatgt tgagtgatcc cactcgtctt aaaattctgc tatatctgaa agacggggaa
    24361 caaaatgtga cagcaatcac ccaagcagtg gaaatggagc agtctgctgt atcgcatcaa
    24421 ctacgtttat taagagaaaa tcatgtcgtc aagtctcatc gcgagggaaa agcgattttg
    24481 tatagtcttg atgattctca tgtactggat attttgaacc agacactcaa acatgtggaa
    24541 catcaataac gataggtgca aatagataaa cactggagtg tgacaacgaa atttcttcgt
    24601 tgtcacactc cagtgttttt taagaaaaag acaaaaatga ttaatcgctt ttttctgttg
    24661 tttcagttcc ataataacta tgatcttcta ggtctaaagc attcaaaata agcgaagccg
    24721 tttcttcaat agataaagat gccacattga tcactacaca tcctagtttt tcataaagat
    24781 cattcgcaaa atcgagttca gctctaattt tttcgatatc ggaataagca gtatcagggt
    24841 ttaatccgta agagcgcatc cgttctttac ggatattatt taaaatatct gggttattcg
    24901 ttagtcccac gattttttta ggatcgatct cccaaagctg tttgggaata tgtgcttgtg
    24961 ggatcaaagg taaattggca acttttaaat ttttgttagc taaaaacaag ctcaaaggcg
    25021 ttttggaagt tcgggatacg cctagcaaaa cgacatctgc ttctaaaaaa ccacgaggat
    25081 ctttcccatc atcgtatttt acagcaaatt ccattgcttt gatccgtttg aaatagttct
    25141 cattcaataa atggagggca ccaggttgcc gaattggctt gataccggtt aaacgttcaa
    25201 tttctgatat cggtggcgtc atcacatcaa aactaaataa ttgatgttct tcacaaaaag
    25261 aacgtgttat ctcgatcagt tcttgattga ttaatgtatg caggacaagt gctttttctt
    25321 ctaatgcatc ttgcaatgcc tgctttaatg ttttttcatc tgtcacgaac gttctgcgga
    25381 ataggttgaa ctcaacggta ggatactgag ccatagtagc ttgcgctagt tttgtcgcag
    25441 tttctccagc agagtcggag atgacaaaaa aagtaacgat ttctgtagaa tcggaagaca
    25501 tggataaaac ctcacttgca ttttttttat gtttattata ccatactcta gaatgcgtac
    25561 ttcgtaatca ttttgatttg gaggaataag tcatgaaaaa acagacattg atcgaacaat
    25621 cattagaaac attgaaaaat aacggtttta aatatactaa aaaaagagaa gcattgttaa
    25681 cttatttagt gaagcgtaac cgctacgtat ctgctaaaga agtttttgac tatatgaatc
    25741 aggaattcaa aggggtaagt tatgatacga tttatcggaa tctccatgat tttgcagaga
    25801 tcgatttact ggaagaaacc gatttaaatg gagaaatgaa gtttcgtttt cattgctgtc
    25861 agggggaaat cggccatcac catcatttta tctgtacagt gtgcggaaca acgaaagaaa
    25921 tccatatgtg tccgatgaat tatttcgaag aacagctagg tggatgcacg atcgaagggc
    25981 atagattcga gattttcgga agatgtgaaa attgtcaata agggtttaaa taaaataaca
    26041 tttgataatt ttaaaaaaaa gcaagatttc cttgacggtc aaaacagcat tagatataat
    26101 atttacagga cagtcttgtt ttttgagata tatttcaata acaattacgg ttacttttta
    26161 agctcggagg gagggaatta acatgtcaaa aacagtcgtt cgcaaaaacg aatcacttga
    26221 cgatgctctt cgtcgcttca aacgttccgt gtcaaaagcg ggtactttac aagaatctcg
    26281 taaacgtgaa ttctacgaaa aaccaagtgt aagacgcaag aaaaaatctg aagcagctag
    26341 aaaacgcaaa aaattctagt tctgtgatga attggagttg gtagtgtgtc actactaagt
    26401 agattaaacg atgacatgaa agcagcgatg aaagcgaaag ataaggaatc tttacaagtc
    26461 atccgaatga tcaagtcatc tatacaaaac gagcagatta aagaaggtca cgacttgaca
    26521 gaagaagaag aactaacggt gttgtctcgc gaaatgaaac agcgacgtga ttctttgcat
    26581 gagtttgaag aagcaggacg tgacgattta gctgaaaaag taaaaagtga aattgtaata
    26641 gtcgaaaaat atatgccgga acaactttcc gatgaagaaa ttcgacaact tgttcaagaa
    26701 gcaatcactc aaactggtgc ttcatcaatg aaagaatttg gcaaagttat gggtgcaatt
    26761 atgcctaaag tcaaaggaaa agcagatgga aaccaagtga atgcgattgt gaaagaacta
    26821 ttacaatctt aattttatca tttaaactgc ggacagtgat tgtccgcagt tttttgtgtt
    26881 cgtaaaaaaa gaactaaaaa
//
LOCUS       DAFBVQ010000035        26423 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.035, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000035 DAFBVQ010000000
VERSION     DAFBVQ010000035.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.035"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(81..1028)
                     /gene="arcC"
                     /locus_tag="LLC22_001659"
     CDS             complement(81..1028)
                     /gene="arcC"
                     /locus_tag="LLC22_001659"
                     /EC_number="2.7.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbamate kinase"
                     /protein_id="HBK5434941.1"
                     /translation="MAKRKVVVALGGNAILSTDASAKAQQEALMETAKYLVKFIEQGD
                     ELIISHGNGPQVGNLLIQQQAADSEKTPAMPLDTCVAMTEGSIGYWLQNAMGEVLKEK
                     GIDKDVVSLVTQVIVDENDPSFKNPSKPVGPFYTEEEAKEQMNADSTVTFKEDAGRGW
                     RKVVASPKPISIKEARVIETLVDQGVITVSVGGGGIPVVETATGLEGREAVIDKDFAS
                     EKLAEIIDADLLIVLTGVDNVYVNYQKPDQKKLETVTVSEMKQYIDEKQFAPGSMLPK
                     VEAAIAFVEAKPNAKAIITSLENIENLLASEEGTIIVAD"
     gene            complement(1143..2162)
                     /gene="argF"
                     /locus_tag="LLC22_001660"
     CDS             complement(1143..2162)
                     /gene="argF"
                     /locus_tag="LLC22_001660"
                     /EC_number="2.1.3.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003073325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ornithine carbamoyltransferase"
                     /protein_id="HBK5434942.1"
                     /translation="MKESVFQGRSLLAEKDFTKEELQYLIDFSEHLKDLKKRGIPHHY
                     LEGKNIALLFEKTSTRTRSAFTTAAIDLGAHPEYLGANDIQLGKKESTEDTAKVLGRM
                     FDGIEFRGFSQKMVEELAEFSGVPVWNGLTDEWHPTQMIADFLTIQENFGTVEGITVA
                     YCGDGRNNMANSLLVTGAILGANMRIVAPKELQPEEEIVKMAEGFAEKSGAQLMITDD
                     VDKGVDGADVLYSDVWVSMGEEDKFEERIKLLKPYQINMEMVEKTHNTDRLIFLHCLP
                     AFHDTNTVYGEQMKERFGITEMEVTDEVFRSKYARQFDQAENRMHSIKAIMAATLGNL
                     FIPRV"
     gene            complement(2253..3482)
                     /gene="arcA"
                     /locus_tag="LLC22_001661"
     CDS             complement(2253..3482)
                     /gene="arcA"
                     /locus_tag="LLC22_001661"
                     /EC_number="3.5.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338827.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine deiminase"
                     /protein_id="HBK5434943.1"
                     /translation="MDKPIHVFSEIGKLKTVLLKRPGQEVENLTPDIMDRLLFDDIPY
                     LPIAQEEHDNFAKTLQNEGVETLYLEKLAAEAIDAGNVKEQFLNKMLDESHIASNAVR
                     EGLHEFLLSMETQEMVDKIMAGVRTKDIEVRSSSLYDLSADDDYPFYMDPMPNLYFTR
                     DPSASMGNGMTVNKMTFEARRRESMFTEYILKHHPRFANKGIEVWLDRENPDHIEGGD
                     ELILSDKVVAVGISQRTNAKALEKLARHLFAKNSGFEKVLAIKIPNNRAMMHLDTVFT
                     MVDHDKFTIHPAIQSKDGKMDVFTIEPDGDDIKITHSDNLHETMKAALGLDDLVLIPT
                     GNGDEIVAPREQWNDGSNTLAIAPGVVVTYNRNYVSNELLRSYGIKVLEINSSELSRG
                     RGGPRCMSQPLVREDLK"
     gene            3943..4644
                     /locus_tag="LLC22_001662"
     CDS             3943..4644
                     /locus_tag="LLC22_001662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Crp/Fnr family transcriptional regulator"
                     /protein_id="HBK5434944.1"
                     /translation="MRVNKIDFHFSKLRYQPDFEHFSDEEFQQIKEHTVLRSYKKGQI
                     LFDDGDPRQRLYILTKGLVRLERYDESATYYYYDYVNTNNLFPMSGMFGEETYTYTAQ
                     AMTDIETFYLPVSYYEKLARKNPEQLIYMIQKISKVVEIHELRIQIGLTSSAFDRVKQ
                     NLFILKEELGVPTKDGHITIPYPITLKELAVNSGTTRETAGQVIKQLRDSGLLDYDKK
                     RFTFCKTATTPAMRE"
     gene            complement(5253..6269)
                     /gene="tsaD"
                     /locus_tag="LLC22_001663"
     CDS             complement(5253..6269)
                     /gene="tsaD"
                     /locus_tag="LLC22_001663"
                     /EC_number="2.3.1.234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     transferase subunit TsaD"
                     /protein_id="HBK5434945.1"
                     /translation="MNEELILAIESSCDETSVAVVRNGTEILSNIVASQINSHKRFGG
                     VVPEVASRHHVEQITLCLEDALVEAGVSAEDLSAVAVTYGPGLVGSLLIGISAAKAFA
                     WAHQLPLIPVNHMAGHIYAARLVKPFQFPLMALLVSGGHTELVYMQEDGSYEIIGETR
                     DDAAGEAYDKVGRVLGLSYPSGKEIDQLAHQGKDNYHFPRAMIHEDNYDFSFSGLKSA
                     FINLVHNAQQRGEDLDKNDLAASFQASVIDVLITKTLRACQNYPVKQLIIAGGVAANQ
                     GLREGLQDALATKLPEVELVIPPLRLCGDNAAMIGAAAHVEMQKRNFASYQLNADPSL
                     VLSE"
     gene            complement(6266..6730)
                     /gene="rimI"
                     /locus_tag="LLC22_001664"
     CDS             complement(6266..6730)
                     /gene="rimI"
                     /locus_tag="LLC22_001664"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBK5434946.1"
                     /translation="MICRKKDFDEAYLAECVWMISENAYPHGSPWTKMQFLADIQQPH
                     SDYLLLAEDNQICGFIGYSKVIDEVEITNIAVAVSEQGKGHARHLLQLLITEQIKDSL
                     HVFLEVRLSNEAARKLYESEKFRILGKRKSYYRNPTEDAIIMSRKLKTETMK"
     gene            complement(6737..7279)
                     /gene="rimI"
                     /locus_tag="LLC22_001665"
     CDS             complement(6737..7279)
                     /gene="rimI"
                     /locus_tag="LLC22_001665"
                     /EC_number="2.3.1.266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal protein S18-alanine
                     N-acetyltransferase"
                     /protein_id="HBK5434947.1"
                     /translation="MLKKFRAYARSFFQDKMIYTEKTVEQIDRRYVLRELTTEDIKEL
                     LDVEREVYNGELPWTKSAFISELKSPLPHLYLGIFDNGRMIGFIGSRAFGLDCHITNI
                     AVRPAYQRKRIGSLLIDEIENFAIMNRCETMSLEVRMSNQDAQRLYRKLGFQATTIKK
                     RYYTETKEDALDMIKLLENE"
     gene            complement(7263..7985)
                     /gene="tsaB"
                     /locus_tag="LLC22_001666"
     CDS             complement(7263..7985)
                     /gene="tsaB"
                     /locus_tag="LLC22_001666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326913.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA
                     (adenosine(37)-N6)-threonylcarbamoyltransferase complex
                     dimerization subunit type 1 TsaB"
                     /protein_id="HBK5434948.1"
                     /translation="MITLGIDTANQTLAIGVVEDEQILGQIQTNIKRNHSVTLMPAID
                     QLFADLQISPKDIDRIAVSDGPGSYTGLRIGVTTAKTIAYTLDKELVGVSSLKTIAAN
                     CIGVDNIIVPMFDARRKNVYAGAYRWKENRLETVLEDVHISASDLFTQLQKLNEAIYF
                     VGSDCHKFFSEIKEILPSAMINTVPAWDIPSGVTVAQLGALVEPVAEKQAFLPRYLKR
                     VEAEEKWLETHTPGDESYVEKI"
     gene            complement(8176..9156)
                     /locus_tag="LLC22_001667"
     CDS             complement(8176..9156)
                     /locus_tag="LLC22_001667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434949.1"
                     /translation="MATIKDIAQLAGVSPATVSRVLNYDPDLSVGLATKQKIFEAAER
                     LNYTKHRKNAANTKQTLRLIQWYDDTEELEDLYYLSIRLGIEKKAEEANVTLLKETWD
                     SISDLPADGTIALGKFDEAQLLEMKGSQNALLLVDSDGTSQGIDSLVVDFKSSVQKVI
                     EHFVSHKAQHIAMLAGTEYTKKNHQRLKDPRIMAFQQVLAEKGYDEGPIIEADFSVES
                     GYQAVKQYLKTNPHVPDALFAANDALAIGALKAIQEKGLVVPEDISVMGFNDVSVAKY
                     VTPSLSTVKVYTEWMGELAVETILQLSNSKAPVSRKIIVETELIIRESTK"
     gene            complement(9180..10664)
                     /gene="galT"
                     /locus_tag="LLC22_001668"
     CDS             complement(9180..10664)
                     /gene="galT"
                     /locus_tag="LLC22_001668"
                     /EC_number="2.7.7.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose--hexose-1-phosphate
                     uridylyltransferase"
                     /protein_id="HBK5434950.1"
                     /translation="MSISQTICDFATLAIEAGGWMEMDRLYLQNRLLGMVGEDALESI
                     EVRPVKEESVDLLDQLVAKARENGVLSELPAEQEIFEAQLMDFLTPPPSVVNAFFAQH
                     YSKSPEEATEYFFNLSKKNDYIKTRAIAKNIKFPAESEYGELEITINLSKPEKDPKQI
                     AAEREAVKVDYPTCMLCMENEGYRGRLNYPARTNHRIIRMNLDGESWGFQYSPYAYYN
                     EHSIILSEQHRPMKITKETFARLLRITEVLPHYFVGSNADLPIVGGSILSHDHYQAGR
                     HEFPMAKAPIEKLIKLEDYPQVIAGVVKWPMSVIRLQSTEKNLLIEAANSVLEKWKAY
                     SDETVSIRAFSADGTPHHTITPIARRRDNYFELDLVLRDNNVSEEHPDGIFHPHKDVQ
                     HIKKENIGLIEVMGLAVLPPRLKPELVEVEHFLLGEENQMAEYHRPWAEQLKKEHPDL
                     TKDTVTDVVQKSVGQVFARVLEDAGVFKRDEKGQAAFERFTAIL"
     gene            complement(10676..11665)
                     /gene="galE"
                     /locus_tag="LLC22_001669"
     CDS             complement(10676..11665)
                     /gene="galE"
                     /locus_tag="LLC22_001669"
                     /EC_number="5.1.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-glucose 4-epimerase GalE"
                     /protein_id="HBK5434951.1"
                     /translation="MTILVLGGAGYIGSHAVDQLVQKGYQVAVVDNLLTGHKQAVHPD
                     AHFYEGDIRDKEFLRSVFEKEPIEGVIHFAASSLVGESVEKPLMYFNNNVYGMQILLE
                     VMHEFNVNKIVFSSTAATYGEPKESPITEDTPANPKNPYGESKLMMEKMMKWCDQAYG
                     MRYVALRYFNVAGAKADASIGEDHTPETHLVPIILQVALGQRKALAVYGDDYDTPDGT
                     CIRDYVQVEDLIAAHILALEYLKEGNESNFFNLGSSKGYSVKEMLEAAREVTGKEIPA
                     EIAPRRAGDPSRLVASSEKAREILGWKPEYTDIKAIIKTAWDWHVSHPNGYEE"
     gene            11913..12080
                     /locus_tag="LLC22_001670"
     CDS             11913..12080
                     /locus_tag="LLC22_001670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3042 family protein"
                     /protein_id="HBK5434952.1"
                     /translation="MKKFVSGILVGSLATAAAVAGLVASVKKTVIDPIDEKEAMIEEN
                     RKKAMRKRVSR"
     gene            complement(12142..13953)
                     /locus_tag="LLC22_001671"
     CDS             complement(12142..13953)
                     /locus_tag="LLC22_001671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD/NAD(P)-binding protein"
                     /protein_id="HBK5434953.1"
                     /translation="MKIGIIGAGPRGLSVAERILHNNQDRHSLELFLFDPNGPGGRVW
                     RLNQPPELLMNSVSQQVTLFTDETLSSGGLVTQGPNLFQWSKGPATDYIEQTVTKNKQ
                     LIIEEINRLEKDQQSTRCLYGLYQRWFFSKLQEEFPASIQFVYSLVKKVSKRKDGYLL
                     QTDQQSYSIDQLVLASGHWENDETEEERVWVDYAKKNVLLYQLPSNPADVDLSKIPPK
                     ENVFLRGLGLSFFDYVGLFTVSRGGRFENEKGKLVYHPSGKEPIVYSGSRRGLPYYPR
                     GRNQKQGGAMAWPRLLTNENLEQWHQSGFLTGETFFDYLKKDVELFYYKKIIEEYHLP
                     IPKKNFEHDFLSLSSEECLGKHPALIPYRWDWSYLETPLAYQNEPFSEASRIFIEGQI
                     KEAEKGNCTGAFASTFDALKDWRDPIRQAIEWHVFSAKEYKEILWGWFTHLNSFLTIG
                     PPIIRTKELAALIDAGIFHLIEPPFDIQQKHNRYVISLQDKEISSRYLIEARLPQTSF
                     SRSSNPVIKNLKENKLVRPFSFSDNTGSYHSEAIDVERGTNRVIDASGEIQSDFYCYG
                     IPVEGVDWLTAAVARPYTDPWNLRQADKIAQLILTDK"
     gene            complement(13950..14315)
                     /locus_tag="LLC22_001672"
     CDS             complement(13950..14315)
                     /locus_tag="LLC22_001672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF488 family protein"
                     /protein_id="HBK5434954.1"
                     /translation="MIKLKRVYLDAEKEDGYRILVDRFWPRGISKEKAQLDLWLKEIA
                     PSNEARKTFDHVPERFASFAKKYQQELIFEEEKKQAIFKLSQLMKEHPVITFVYGAKN
                     EHQNHAVLLKKFIEMEACK"
     gene            complement(14478..14873)
                     /locus_tag="LLC22_001673"
     CDS             complement(14478..14873)
                     /locus_tag="LLC22_001673"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhodanese-like domain-containing protein"
                     /protein_id="HBK5434955.1"
                     /translation="MVLWVINIILLLIVLAIILWEVYLRVMAKRSATTLTEEEFREGM
                     RKAQVIDVREKDVFDAGHILGARNIPYTVLKDSLGSIRKDQPVYIYDQKKSLSIRTAN
                     KLRKAGYQEIYLLKGGYDGWSGKIKSKKV"
     gene            complement(14891..15853)
                     /locus_tag="LLC22_001674"
     CDS             complement(14891..15853)
                     /locus_tag="LLC22_001674"
                     /EC_number="2.7.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879491.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family glucokinase"
                     /protein_id="HBK5434956.1"
                     /translation="MDKKIIGIDLGGTTAKFAILTPEGEIQQKWSIDTNILDDGKHIV
                     PEIIESINHRLNLYNMKAEDFIGIGMGTPGSVDSEAGTVIGAYNLNWTEVQFVKKLIE
                     AGTGIKFAIDNDANVAALGERWKGAGENDPDVVFVTLGTGVGGGIVAGGNLIHGVSGA
                     GGEIGHITVDPEGFECTCGKRGCLETVSSATGVVRLGRFLAEEYAGDSKLKAMLDNGE
                     EVTSKDIFEMAQEDDPFALMVVDRVCFYLGLACGNLGNTLNPSSIVLGGGVSAAGEFL
                     RSRVEKYFKEFTFPQVRESTKIKLAELGNEAGVIGAASLALKFA"
     gene            complement(15853..16065)
                     /locus_tag="LLC22_001675"
     CDS             complement(15853..16065)
                     /locus_tag="LLC22_001675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqgQ family protein"
                     /protein_id="HBK5434957.1"
                     /translation="MESLYDVQQLFKKFGIFIYVGARIYDIELMTIELRNLYDSRLID
                     HDTYMTAWRILKREHRIEESRKKGNL"
     gene            complement(16086..16784)
                     /locus_tag="LLC22_001676"
     CDS             complement(16086..16784)
                     /locus_tag="LLC22_001676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhomboid family intramembrane serine protease"
                     /protein_id="HBK5434958.1"
                     /translation="MNYQQQIKLRAWLRRPLWTYAFLGIQTAVFLMMELFPRLEIPYY
                     AGMYGPYLVHFNEWWRLVTPIFIHFGLMHFVMNSLILYFMGQQIEAIYGHWRFFLIYM
                     FSGIMGNTASFAFNEANVLSGGASTSIFGLFGALFILGFHFKHNPAIQQLVRHFLLFI
                     VLTFVFGLLDTSVDVWGHVGGLIGGLVLGNVLGLPKQQTSYSIHQRILSTLVFVFLFV
                     ICILLGLKKYGLLV"
     gene            complement(16804..17346)
                     /locus_tag="LLC22_001677"
     CDS             complement(16804..17346)
                     /locus_tag="LLC22_001677"
                     /EC_number="6.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-formyltetrahydrofolate cyclo-ligase"
                     /protein_id="HBK5434959.1"
                     /translation="MDQLKVRLRRKGIEKLKNLAKSGKKKEKEQRIYKQLFASEYWKS
                     AKVIGTTLSNEFELDTQPVIQRAEKEQKKIVVPKTLPKRQMAFYEMDEQSVLVRSSFG
                     VLEPQSEKLYLPEMIDLLIVPGIIYNRAGYRIGFGGGYYDRYLNNFHKKTCSLVFREQ
                     LNEQWQPESFDQKIQQLFID"
     gene            complement(17478..18482)
                     /locus_tag="LLC22_001678"
     CDS             complement(17478..18482)
                     /locus_tag="LLC22_001678"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343565.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBK5434960.1"
                     /translation="MKKIYWTFYFLLFVLVILSIGSLMIGTPFIYLDQLFATFIGKES
                     SSLALIVREFRVPRLLISLLAGACLGVSGYILQGVTRNELADSSILGINAGAGFLVML
                     YLGFFSHYSLPFLLLVVAFLGGVLAACCVYLAAYDRNGFLGMNRILLSGIAVNAGLSA
                     LTLLCTIQLSKENYGFVNAWLAGSIWGASWPYVWALLPWAVILIPLGGLYAQRIVLLS
                     FGQERAQGLGLNVAKSQKILLLLAVALASGSVAVTGSLSFVGLLAPHAAKLVVRKENN
                     WTFVLSGLFGSIFLLSADMVARVILLSGEVPTGILIALFGAPYFLYALFIRQKHALNS
                     "
     gene            complement(18479..19468)
                     /locus_tag="LLC22_001679"
     CDS             complement(18479..19468)
                     /locus_tag="LLC22_001679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron ABC transporter permease"
                     /protein_id="HBK5434961.1"
                     /translation="MRTMKKNRLLLLVCFVLLIIFFVALSNGAATVGKADFWQALFDF
                     DRSKQSHQIIRNIRLPRVAGAFLVGSCFALSGALMQGVTRNPLADSGLLGINAGASLA
                     MALSFAFWPKASDFSVFLMSLAGSFAVTLLVFGFLQFSKMGMNPLQLILAGVAISSFF
                     TAISQALTQFFNLQQDLAFWFVGGAANITWKQLAVLFPLYILAVLVSFSLGKAISLIH
                     LSETHALALGSHPKRTRLIVFCLVAVLAAIAVSLVGPVSFIGLLVPPVVRGMVGTDYR
                     YVLPVSFLVGGGLVMLADFTARMINPPFETPFGLVIALIGVPFLLIQVRREQR"
     gene            complement(19465..20271)
                     /locus_tag="LLC22_001680"
     CDS             complement(19465..20271)
                     /locus_tag="LLC22_001680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434962.1"
                     /translation="MTRLRAADIAAGYENKKIIENMSVTIPEGKITSLIGPNGSGKST
                     LLKSFTRILPVKSGKIIVNNSDISTYSSKELAKKIALLAQTSEHPTGMTVEEVVSYGR
                     YPYQKLFSGMDTQDHEAIEWALDATGLAGFRMRDIATLSGGQTQRVWIAMALAQETDI
                     LILDEPTTFLDPAHQLEILQLLTEINQMKQTTILMSIHDINHASRFSDYLLAMKNGKL
                     ITEGTPEEVITKECMKKIFEIDATIVTLPRTNKPVFLTYDLLPKEQEDQL"
     gene            20437..21393
                     /locus_tag="LLC22_001681"
     CDS             20437..21393
                     /locus_tag="LLC22_001681"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5434963.1"
                     /translation="MKLKTKVFTLSSILLLAGVLSACSPSSDKETATTANSTTSSNST
                     HTVTDTLGHKVEIPNAPKRIIGSYLEDYLIALGEKPIAQWTVGSGSIQDYLQDDLKDV
                     PTISYDLPYEKVLSFEPDLLLISSSATVEGGKYEQYSKIAPTYVVKNGTDVTWEEQLK
                     DVGKALAKEKEAEKIISDYQKSIKKTREELADKIENKTAAVLWVTNNSAFMVSKNRSS
                     GRIVYDDLEFGVPDLVEEVSKKATSDWSAVSSEKLAELDADYIILVNSDKDAAMFNEP
                     SWKNLKAVTDNHVLQFGPESSWLYNGPIASQEMVNDIKEKLN"
     gene            complement(21470..21988)
                     /locus_tag="LLC22_001682"
     CDS             complement(21470..21988)
                     /locus_tag="LLC22_001682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306410.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5434964.1"
                     /translation="MFISMWAQDKNGLIGKNGLLPWRLPNDMRFFREHTMDRILVMGR
                     KTYEGMGDLSLPYRHIIVLTTQPNFRTKENAEVMHSIDELLSYSQTISEDIYVSGGSR
                     IFQELLPYTGRIWRTLIDSTFEGDTYIGNIDFSDFALIEEYEGITDQENLYAHRFQKW
                     ERVKNRVASKEE"
     gene            complement(22076..22225)
                     /gene="rpmG"
                     /locus_tag="LLC22_001683"
     CDS             complement(22076..22225)
                     /gene="rpmG"
                     /locus_tag="LLC22_001683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBK5434965.1"
                     /translation="MRVNITLECTSCKERNYLTSKNKRNNPDRLEKQKYCPRERKVTL
                     HRETK"
     gene            22453..22899
                     /locus_tag="LLC22_001684"
     CDS             22453..22899
                     /locus_tag="LLC22_001684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371264.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2188 domain-containing protein"
                     /protein_id="HBK5434966.1"
                     /translation="MPWNMKDFPASMKNLDKLTRKKAIDIANALLDEGYPDNRAIPIA
                     IDQAKKWYEDASESEKRTFEKEKNPSKTDEHDTNPRAGKLLDSDVIVEYEEEQWIVKS
                     KGAKKASNHFDTKKEAIEKGKQVAQNKESTLFIYKKDGTKEKEIDY"
     gene            complement(23094..24989)
                     /gene="asnB"
                     /locus_tag="LLC22_001685"
     CDS             complement(23094..24989)
                     /gene="asnB"
                     /locus_tag="LLC22_001685"
                     /EC_number="6.3.5.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine synthase (glutamine-hydrolyzing)"
                     /protein_id="HBK5434967.1"
                     /translation="MCGIVGFVNDKDNKKTIINTMMDRIVHRGPNSSGEYIDKHVALG
                     FRRLSIIDLEGGTQPIYNEDRTKIIIFNGEIYNYQPLREELIAAGHVFQTHADTEVLL
                     HGYEEWGTELLQKIRGMFAFAIWDNEKNELFGARDHFGIKPYYYAEMNGTFMFGSEIK
                     SFLPHPDFNKELNKEALKPYMTFQYSPLNGETFFKDVYRLPEGHYYTYKDGKIDIQQY
                     WDADFETKETHSRQEWIEKIDETVQASIEAHTVSDVEVGSFLSSGVDSSYVTSVLKPD
                     HSFSIGFDDKTYNETIEARKLTELLDLDNTAAVIDGDMSFKAFPLIQYHLDEPDSNPS
                     CVPLYFLANLASQSVRVVQSGEGADELFAGYQTYGFHTNSKFIRVIAQGLKKLPKGTR
                     YNLGRKIGKMKNFHGRIHLYESLAPAKEYFIGHARVFEESEASEVLTPKYQTAPSVDE
                     IMTVHYEKTEGIKDEVNKMQYVDLHQWMPKDILLKADKLSMASSLEVRVPLLDIEVMK
                     LAQQIPSKFLLNQNNTKDIFRQAANKHLPEKWSNRVKLGFPVPIKAWLKEEHGYEQVK
                     ALFEADFAKEFFDQEKIMKLLDDHHEGRKEEQRKIWTIFSFLTWYKVYFVDETIPQAE
                     AIDYVTV"
     gene            complement(25314..26288)
                     /gene="bsh"
                     /locus_tag="LLC22_001686"
     CDS             complement(25314..26288)
                     /gene="bsh"
                     /locus_tag="LLC22_001686"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBK5434968.1"
                     /translation="MCTAITYATKDHYFGRNFDYEMSYNEVVTITPRNYRFDFRKVKN
                     LDKHYAMIGIAAGVSNYPLYYEATNEKGLSMAGLNFPGNADYKELQEGKDNVAPFEFI
                     PWILGQCSTIDEAKELLATINLVNIDFSEKLPLSPLHWLLADKEKSIVIESMKDGLHL
                     YDNPVGVLTNNPPFDYQLFNLNNYRSLSNGTPENHFSNQISLNVYSRGMGGLGLPGDL
                     SSVSRFVKATFTKMNAASGDSESESISQFFHILGSVEQQKGVCDTGERKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAVNMNKEDLDRHELVSYPVIKEQQINYVN"
BASE COUNT         7859 a         5555 c         4521 g         8488 t
ORIGIN      
        1 aaaatccaga tggcctaaag gagaagaaat accacctgga tagctataaa tcatttcgta
       61 aatacgaaag acttaacaaa ttaatcagct acgataatcg ttccttcttc agaagctaaa
      121 agattctcga tattttctaa agaagtgatg attgccttag cgtttggttt tgcttcaaca
      181 aatgcaatag ctgcttctac tttcggaagc atgcttcctg gagcgaattg cttttcatca
      241 atgtattgtt tcatttctga aacagtaaca gtttctaatt tcttttgatc tggtttttgg
      301 taattgacat acacattgtc tactcctgtc aatacgatca gcaaatccgc atcgatgatt
      361 tcggctaatt tttctgaagc aaaatcttta tcgattacgg cttctcgtcc ttctaatcca
      421 gtagctgttt ctacaacagg aatcccaccg ccaccaacag agactgtgat aactccttga
      481 tcgaccagcg tttcgatgac acgtgcttct ttaatcgaga tgggtttagg ggaagcgact
      541 acttttctcc atccacgtcc agcatcttct ttgaatgtca cagtggagtc agcattcatt
      601 tgttctttgg cttcttcttc cgtgtagaat ggaccgactg gtttacttgg atttttgaat
      661 gaaggatcat tttcatccac aataacttga gtgactaaag aaaccacatc tttatcgatc
      721 cctttttcct tcagtacttc gcccatggcg ttttgtaacc agtaaccgat agatccttct
      781 gtcattgcaa cacatgtatc taaaggcatt gccggtgttt tctcagaatc agcagcttgc
      841 tgctgaatca ataggttacc gacttgcgga ccatttccgt gggagatgat caattcatct
      901 ccttgttcga taaatttcac taaatacttt gctgtttcca ttaacgcttc ttgttgggct
      961 tttgcacttg catccgtaga caagatggca ttgcccccta aagcgacaac tacttttcgt
     1021 ttggccattt cattcgtcct ttcttcagtt ctaccgaatt ttctagataa caaaacgagc
     1081 cagcgttttg tgattttccc tcaatgctga ctcgtttttt cgtgagatga atgtggttat
     1141 gcttaaacgc gagggataaa caagttacct aatgttgctg ccatgatcgc tttgattgag
     1201 tgcatacgat tttctgcttg gtcaaattga cgagcatatt tgctgcggaa gacttcatct
     1261 gttacttcca tttcagtgat gccaaagcgt tctttcattt gttcaccgta aacagtgttt
     1321 gtatcatgga aagctggcaa gcagtgcaag aagatcaaac gatctgtgtt gtgtgttttt
     1381 tctaccattt ccatattgat ttggtaaggt ttcaacaatt tgatacgttc ttcgaattta
     1441 tcttcttcac ccattgatac ccatacatca gaataaagga cgtctgctcc gtctacacct
     1501 ttatcaacat cgtcggtaat catcaattgt gcaccggatt tttcagcaaa gccttctgcc
     1561 attttgacga tttcttcttc aggttgtaat tcttttggtg caacgatacg catattcgct
     1621 cctaaaattg cacctgtgac taataaagag ttagccatat tgtttcgacc atctccgcag
     1681 taagcaacag tgataccttc tactgttcca aagttttctt ggatagttaa aaagtcagcg
     1741 atcatttgtg ttggatgcca ttcatcagtc aagccattcc aaactggaac accagagaat
     1801 tctgctagtt cctctaccat tttttgactg aatccacgga attcgattcc gtcaaacata
     1861 cgtcctagta ctttagctgt atcttctgtg gattcttttt tacctaattg gatatcattt
     1921 gcacctagat attcaggatg tgcacctaga tcgatcgctg cagtagtaaa tgcagaacga
     1981 gtacgtgtag atgttttttc aaataaaagc gcaatatttt ttccttctag atagtgatgt
     2041 gggataccac gttttttcaa gtctttcaag tgttctgaaa aatcgatcaa atattgtaat
     2101 tcttcttttg taaagtcttt ttctgctaat aagcttcttc cttggaatac tgattctttc
     2161 atattaaaca ttctccttta gattgttttt atttaagatt aaagaggaaa tcccgacggc
     2221 agctgacagt aagactgccg tcaggaaaca aattacttca agtcttcacg gacaagtggt
     2281 tggctcatgc agcgtggacc accacgacct cgtgacaatt cacttgaatt gatttctaac
     2341 actttgatgc catagctacg aagcaattcg ttcgatacat aatttcggtt ataagtgact
     2401 acaacacctg gagcgattgc caatgtgttt gatccatcat tccattgttc tcgaggtgca
     2461 acgatctcat ctccattacc agttgggatc agtacaagat catctaatcc aagagcagct
     2521 ttcatcgttt cgtgtaagtt atctgaatga gtaatcttga tatcatcacc atctggttcg
     2581 attgtaaaga catccatctt accgtcttta ctttgaattg ctggatggat agtgaattta
     2641 tcgtgatcta ccattgtaaa tacggtatcc aaatgcatca ttgcacggtt gttcggaatt
     2701 ttgattgcca acactttttc aaatcctgaa ttttttgcga ataggtggcg tgctaatttt
     2761 tctaaagctt tcgcattagt tcgttgagaa atcccaacag ctactacttt atcgcttaag
     2821 atcaattcgt ctccgccttc gatatgatct ggattttcac gatccaacca tacttcgatt
     2881 cctttatttg caaatcttgg atgatgtttc aaaatatatt ctgtaaacat cgattcacga
     2941 cgacgtgctt caaaagtcat cttattgact gtcatcccat ttcccattga tgcggaaggg
     3001 tcgcgtgtaa agtacaagtt tggcattggg tccatgtaaa atggatagtc atcgtctgct
     3061 gacagatcat atagactgct agaacgtact tcgatatctt ttgtacgaac cccagccatg
     3121 attttatcta ccatttcttg cgtttccatt gatagaagga actcatgaag accctctctt
     3181 acagcattcg atgcaatatg agattcatcc aacattttat tcaagaattg ttctttgaca
     3241 ttgcctgcgt caatcgcttc tgccgctaat ttttccaagt aaagagtctc gacgccttca
     3301 ttttgcaatg tcttcgcaaa gttgtcatgt tcttcttgag caatcggaag atatggaata
     3361 tcatcgaaca acagacgatc cataatatct ggtgtcaaat tttccacttc ttgtccaggc
     3421 cgtttcagta aaactgtctt taatttccct atttcagaga aaacgtgaat aggtttatcc
     3481 atgttgtgtt gcctccttct ttttgattac atgtatagga tatcctcctt ttgtaatcac
     3541 tttcataatt ttgtctcatt caaaatgaga cattcctcac attaatattc gataattaaa
     3601 taattaaacg tttttctatt tttaagcgta atttattcat tttttattct gtatacactt
     3661 tcaaaaaaat atttattcat tgaaaaaatt tttttgaata aattaaaaaa ataaattata
     3721 ttatcgttgt tagcgtttac tatatgtatt attgttgttt tttatacaca aatcattcgc
     3781 ttcaaaacaa attattcaat accattgtat attttttaca taataacaaa ttatatttgt
     3841 aaagtattaa aacttgtttc taatgttggt atgttaaaac tttacaaatt ctttaaaaaa
     3901 agtgacaata aatatagtga acaataagga gaggactttt taatgcgtgt taataaaatc
     3961 gattttcact tttcaaaact cagatatcaa cctgattttg aacatttctc ggatgaagag
     4021 ttccaacaga tcaaggaaca tactgttctt cgttcttata aaaaaggaca gatccttttc
     4081 gacgatggtg atcccagaca acggttgtat atcttgacca aaggactcgt tcgtttagaa
     4141 cgttatgatg aaagtgcaac ttattactac tatgactatg tgaatacaaa taaccttttt
     4201 cctatgtcag gaatgtttgg agaagagacc tacacttata cagctcaagc gatgactgat
     4261 attgaaacat tctaccttcc tgtttcctac tatgaaaaat tagcacgaaa aaatcccgaa
     4321 cagttgatct atatgataca aaaaatttct aaagtagttg aaatacatga attgcgtatc
     4381 caaatcggat tgacctctag cgcctttgac cgggtaaaac aaaatttatt cattttgaaa
     4441 gaagaattgg gcgtaccaac aaaagatggt catatcacca ttccttatcc gatcacctta
     4501 aaagaattag cagtgaatag cggcacgaca cgtgaaactg ctggacaagt aatcaaacaa
     4561 ctacgtgatt ccgggctgtt agattatgac aaaaagcgtt ttactttctg taagacagct
     4621 actactccag ctatgagaga ataacgcgaa caaaaataag cagtgaccct gataaatatc
     4681 agggtcactg cttattttcc tccctaaaac ttctgaaaga tccggcagtt ttagatcact
     4741 ggacaagact caaagatttt ctatgtgtgt ttcagttatg taatattcac tgtttgcaaa
     4801 aaatactgtt agattaacta gatgaagcgt cttgtcctca tccgatctag attattcgat
     4861 attcctcgac aataaacgat tactcagtga gggcaatcag aggaacggat aatgataaat
     4921 aagctgtaaa aaatagcaaa ataacaataa tgattaaaag tatgtaaaaa atagggcttt
     4981 gacaaaaacg tgtcacagcc ctatttcgat taaacggtgt gtacctgtca actcttcggt
     5041 cacaagtcat aatgttcata aacatgagga gctgtttttt gaaattgttc cttgtgaatc
     5101 agagttaaac gacaggctta cgaactcttg attaaacggc gttcaaaagc ttgcatacgc
     5161 ggtaataaga acagccaggt caaaaacatg agaagccgtt tttcctgggc tgttcttatt
     5221 acttgatgca gggcagcttt ttcacaacct ctttattcag ataaaaccaa gcttggatca
     5281 gcattcaact gatagctagc aaaatttctt ttttgcattt ccacatgtgc tgctgctcca
     5341 atcattgcag cattatctcc acaaagtcga agagggggaa tcactagttc tacctcaggg
     5401 agtttagttg ccaaagcatc ctgcaatcct tcacgcaacc cttgattggc cgctacacct
     5461 ccagctataa tcagttgctt gactggataa ttttgacaag ctcgaagtgt tttagtaatc
     5521 aatacatcga tcacacttgc ttgaaagcta gctgctaaat catttttgtc tagatcttct
     5581 ccacgctgtt gtgcattatg caccaaattg ataaatgcac tttttaatcc gctaaaactg
     5641 aaatcataat tatcttcatg gatcatcgct cgcggaaaat ggtaattatc ttttccctga
     5701 tgagctagct gatcgatttc ttttccgctt gggtaagaaa gacctaatac tcttccaact
     5761 ttgtcataag cttctcctgc tgcgtcatct cttgtctccc caatgatttc atatgatcca
     5821 tcttcttgca tatagactaa ttctgtatgt cctccgctaa caagaagtgc catcaatgga
     5881 aactggaatg gtttaaccag acgggctgca tagatatgcc ctgccatatg gtttacagga
     5941 ataagcggca attggtgtgc ccaagcaaaa gccttagctg cagaaatacc aatcagcaac
     6001 gagccgacaa gtcctggtcc ataagtgaca gcgactgccg ataaatcttc tgccgacaca
     6061 ccagcttcta ccagtgcatc ttccaagcat aaggtgattt gttctacgtg atggcggcta
     6121 gctacttcag gtactacgcc accaaaacgt ttatgactgt ttatttgaga agcaacgatg
     6181 ttagataaga tctctgttcc atttctaacg accgctacac tcgtttcatc acaacttgat
     6241 tcaatcgcca gaatcaattc ttcattcatt tcatcgtctc cgtttttaac tttctgctca
     6301 taatgatcgc atcttccgtc ggattgcgat aatatgattt ccgtttacct aatatacgaa
     6361 acttttctga ttcataaagt tttcttgctg cttcattaga tagacgtact tctaaaaaaa
     6421 catgcagcga atcttttatt tgttccgtaa tcagtaattg taacaaatgc cgtgcatgcc
     6481 cttttccttg ttctgaaact gcaacagcaa tatttgtgat ctcgacttca tctattactt
     6541 tcgagtatcc aataaagcca cagatctggt tatcttcagc taaaagcaga taatcagagt
     6601 gaggctgttg gatgtctgcc aaaaactgca ttttcgtcca aggtgaacca tgtggataag
     6661 cattttcgct aatcatccat acgcattctg ccaagtacgc ttcatcaaaa tctttttttc
     6721 tgcaaatcaa ctaatctcac tcattttcta aaagttttat catatccaac gcatcttctt
     6781 ttgtttcagt gtaatatctt tttttgatcg ttgttgcttg aaaccccaat ttccgataaa
     6841 gtctttgtgc atcttgatta ctcatacgca cttctaatga catcgtctca cagcgattca
     6901 ttatagcaaa gttctcgatt tcgtcaataa gcagcgaacc gattcgttta cgctgatatg
     6961 ccggtcgaac ggcaatattc gtgatatggc aatctaaacc gaacgctctt gaaccgataa
     7021 aaccaatcat tcttccatta tcaaagatac ctagatatag atgaggaagc ggtgacttca
     7081 attctgatat aaaggcactt tttgtccatg gcaattcgcc attatagact tctcgttcga
     7141 catccagcag ctctttgata tcttctgtag tcaattctct tagtacgtaa cgacgatcga
     7201 tttgttcgac tgttttttct gtataaatca ttttatcttg aaaaaagctt ctggcatacg
     7261 ctctaaattt tttcaacata actttcgtct ccaggtgtgt gcgtctccaa ccatttttct
     7321 tctgcttcta ctcgttttaa atagcgagga agaaaagctt gtttctctgc aactggttca
     7381 actaaagcac ctaattgagc cacagttaca ccacttggaa tatcccatgc tggaactgta
     7441 ttaatcatcg cactaggcaa tatttccttt atttcagaga agaatttgtg acaatcactc
     7501 ccgacgaaat aaatagcttc attcagcttt tgtagttgtg tgaacaaatc agaagcagaa
     7561 atatgtacat cttcaagtac agtttctaat ctattttctt tccagcggta tgccccagcg
     7621 tatacatttt ttcttcgagc atcaaacatg ggcacaataa tattatccac accgatgcaa
     7681 ttagccgcga tggttttcag actagatact cctactagct ctttatctaa tgtataagca
     7741 atcgtttttg ctgtcgttac acctatacga agccctgtat aagaaccggg accatcagaa
     7801 accgcgattc ggtcaatgtc ttttggactt atttgaagat ctgcaaacaa ttggtcgatt
     7861 gcaggcatca gtgttacact gtggttgcgt ttgatatttg tttgtatttg tccaagaatt
     7921 tgttcgtctt ctaccacacc gatcgccaaa gtttggtttg cagtatctat tcctaatgta
     7981 atcatatatt tgatcctttc tgctatgaca ttctcgcctt ccattgtagc atactttttt
     8041 attctgagga tgaaaatacc aaaggcaaaa ctagtacaat aatacatgat tatctgctgg
     8101 cgggcaaatt ttgccccttc ctgaaacaca aaaaagctgc ggtatcactc cattttccca
     8161 cagcttttcc atcttttatt tcgttgattc tcgaataatc aactctgttt ccacaataat
     8221 ctttcttgaa accggtgctt tggaattact taattgaaga atcgtctcca ctgctagctc
     8281 tcccatccat tcggtataaa cttttacagt agaaagcgag ggcgttacat atttcgctac
     8341 actgacatca ttgaagccca tcacagaaat atcttctggt accactaaac ctttttcttg
     8401 aatcgctttc agtgcgccaa tcgctaatgc atcattagct gcaaaaagcg catcaggaac
     8461 atgcggattc gtttttaaat actgcttcac tgcttgatat cctgactcga cagaaaaatc
     8521 tgcttcgata attggacctt cgtcgtagcc tttttctgcc aaaacttgtt gaaatgccat
     8581 aattctggga tcttttagcc gctgatggtt tttcttcgta tattctgttc cagcaagcat
     8641 agcgatatgt tgcgctttat gggagacaaa gtgttcaatg actttttgaa cacttgactt
     8701 aaagtcgaca actagagagt cgattccttg agaagtgccg tcagaatcta ccaaaagcaa
     8761 ggcattttgg gatcctttca tttctaataa ctgagcttcg tcgaattttc ctagtgcgat
     8821 cgttccatct gccggaagat cactaatgga atcccacgtt tctttcaata aagtaacgtt
     8881 tgcttcttct gccttttttt cgattcctag gcgaatagat aaataataaa gatcttcaag
     8941 ctcttccgta tcgtcgtacc actggatcag gcgaagcgtt tgcttagtat ttgctgcatt
     9001 tttacgatgt ttcgtataat ttaagcgttc tgctgcttca aaaatttttt gctttgtggc
     9061 taagccaacg gaaagatcag gatcatagtt gagaactctt gaaacagtag caggagaaac
     9121 tcctgccaac tgcgcaatgt ctttaattgt tgccatttgt ctctcctcct tttttacgtt
     9181 tataaaatcg cagtaaatcg ttcaaacgct gcctgtcctt tttcatctcg cttgaatact
     9241 ccagcgtctt ccagtacacg tgcaaaaacc tgacctacag atttttgtac gacatcggtg
     9301 accgtatctt tcgtcaaatc aggatgttct ttttttaatt gttctgccca cggacgatga
     9361 tattcagcca tctggttttc ttctcctaat aagaaatgct ctacttctac tagttctggt
     9421 ttcaaacgag gtggtaaaac agcaagcccc attacttcga tcaacccaat gttctccttt
     9481 ttgatatgtt ggacatcttt atgtggatga aaaatcccat caggatgttc ttctgaaaca
     9541 ttgttgtctc gaaggacaag gtccaactca aagtaattgt cccttcttcg tgcaattggc
     9601 gtaatcgtat ggtgtggtgt accatctgct gaaaaagctc tgatagatac tgtttcatcc
     9661 gaatatgctt tccatttttc caatactgag ttagctgctt caataagcaa gtttttctct
     9721 gttgattgca aacggatcac agacatcggc catttcacga ctcctgcgat gacttgcgga
     9781 taatcttcta gtttgataag tttttctatc ggtgcttttg ccataggaaa ttcatgacgt
     9841 cctgcctgat aatgatcatg agaaagaatc gatcctccaa caattggtaa gtcagcattc
     9901 gaaccaacaa agtaatgagg caagacttca gtaatccgaa gcagtctagc aaatgtttcc
     9961 tttgtgattt tcatcgggcg gtgttgttct gataaaatga tcgaatgttc attgtaataa
    10021 gcataagggg aatattggaa tccccagctt tcaccgtcta gattcattcg aataatccgg
    10081 tgattggtgc gggctggata gttcaagcga cctctatatc cttcgttttc catgcaaagc
    10141 atgcaggtag gatagtctac ttttaccgcc tcgcgttctg ctgcgatttg ttttggatct
    10201 ttttctggct tagataaatt gattgtgatt tccagttcac catactccga ctctgccgga
    10261 aatttgatgt tttttgcgat ggctcttgtt ttgatgtagt catttttctt acttaaatta
    10321 aagaaatact cagttgcttc ctctgggctt ttcgaatagt gctgtgcaaa gaatgcattg
    10381 acgactgaag gtggcggtgt gagaaaatcc attaattgcg cttcaaaaat ctcttgttct
    10441 gctggcaatt ctgaaagaac accattttct cttgccttag cgacaagctg atccaataag
    10501 tctacagatt cttccttaac tggtcttact tcaatgcttt ctagagcatc ttctcctacc
    10561 atccctaaaa gacgattctg taaatataag cggtccattt ccatccatcc gccagcttcg
    10621 atcgcaagtg tggcaaaatc acaaatcgtt tgactgattg acatatctca ttcccctatt
    10681 cttcataacc atttggatgg ctgacatgcc aatcccatgc tgttttgata atcgctttga
    10741 tatctgtgta ttcaggtttc cagcccagaa tctctctcgc tttttcactt gaagcgacta
    10801 atcggctagg atctccagct cttcttggtg ctatttctgc tggaatttct tttcctgtca
    10861 cttctctagc tgcttctagc atttccttga ctgagtatcc tttgctgctg cctaaattga
    10921 agaagttgct ttcatttcct tctttcaagt attccaaagc taaaatatgt gcagcaatca
    10981 aatcttctac ttgaacataa tctctgatac atgttccatc tggtgtatca taatcgtctc
    11041 cataaacagc caaggctttt ctttgaccaa gagctacttg taaaatgatt gggacaagat
    11101 gcgtttctgg tgtatgatct tctccgatag atgcatctgc ttttgctccg gctacattga
    11161 agtagcgcaa agcgacatag cgcatgccat atgcttggtc acaccacttc atcatttttt
    11221 ccatcatcaa tttactttca ccatacggat ttttaggatt agctggtgta tcttctgtga
    11281 ttggagactc tttcggctct ccataagttg ctgcagtaga agagaatacg attttattca
    11341 cgttgaactc gtgcatgact tcaagtaaga tttgcatacc gtatacgttg ttgttgaaat
    11401 acatcaatgg tttttcgaca gattctccta ctaaagagct tgcagcaaaa tggattactc
    11461 cttcaatcgg ttccttttca aatacggaac gtagaaattc tttatcccgg atgtctcctt
    11521 cataaaaatg agcatctgga tgtactgctt gtttgtgacc tgtgagcaaa ttatctacca
    11581 cagctacttg ataccccttt tgaactagct ggtctacagc gtgcgaaccg atataaccgg
    11641 ctccgcctag tactaaaatt gtcataaaaa acactccttt gattagtaaa attgtgtttg
    11701 ttgattctat ataatttaaa aaacgaagtt tacttttatg gtgaaaacaa acaaagtaaa
    11761 atttcgtaaa ttcatatggt aaatttataa taaaacattt agtaaacatt ttcaaggatt
    11821 ttttgcaaag gtttacaaac aaacgtaaaa ctagcctttt tttctctttt gttccataat
    11881 agatataaca aataataaat gaggtggatt caatgaaaaa atttgtatct ggaatattag
    11941 taggaagtct ggcaacagcc gctgccgttg ctggtttggt tgcttctgtg aaaaaaacag
    12001 tgatcgatcc aattgacgaa aaagaagcaa tgatcgaaga aaaccgtaaa aaagcaatgc
    12061 gtaaacgcgt ttctcgttaa taattattta aaaatacgca tgaagacttt ctaaaaaaca
    12121 gataagtcat catgcgtatt tttatttgtc agtcaatata agttgtgcta ttttatctgc
    12181 ctgtctcaga ttccatggat ctgtataagg tctagctact gctgcagtta gccaatccac
    12241 accttcaaca ggtattccat agcaataaaa gtcagactgg atttcccctg aagcatcaat
    12301 cacgcgattc gtacctcgct caacatctat agcttctgaa tgataacttc ctgtattatc
    12361 tgaaaatgaa aaagggcgaa caagtttgtt ttccttcaaa ttttttatga caggattact
    12421 tgaacgagaa aagcttgttt gtggcaatcg agcttcaatc aaatagcgac tgctgatttc
    12481 tttatcttgt agagaaataa catagcggtt gtgcttttgc tgaatatcaa atggcggttc
    12541 gatcaaatga aaaatacccg catctatcag tgctgctaat tctttcgtcc gaatgattgg
    12601 cggaccgatc gttaaaaagc tatttagatg agtaaaccat ccccatagta tttctttgta
    12661 ttccttagca gaaaaaacgt gccattcaat agcctgccgg attggatcac gccagtcttt
    12721 taatgcatca aatgttgaag caaatgctcc tgtgcaattg cctttttccg cttcttttat
    12781 ctgcccttca ataaatattc ggctagcttc tgaaaagggc tcattctgat aggcaagagg
    12841 agtttctaaa tacgaccaat cccatctata agggattagt gctggatgct ttccgagaca
    12901 ctcctctgaa gagagggaga gaaaatcatg ctcaaaattt ttctttggaa tcggcaagtg
    12961 atattcttcg atgattttct tgtaataaaa caactcaacg tcttttttca gatagtcaaa
    13021 aaatgtttcg ccagtcaaaa atcccgactg atgccattgc tccaggtttt catttgttag
    13081 taaccgtggc catgccattg ctccgccttg cttttgattt cttcctcgag ggtaataagg
    13141 gagccccctt cttgatccac tgtatacaat cggttccttg cctgatggat gatagaccag
    13201 ttttcccttt tcgttctcga agcgccctcc tcttgatact gtaaacaatc cgacataatc
    13261 aaaaaaactt aagcctagac ctcttaaaaa gacattttct ttaggcggta tcttcgaaag
    13321 atctacatct gcaggattag aaggaagctg atacagtaaa acatttttct ttgcgtagtc
    13381 tacccacact ctttcttctt ctgtctcatc attttcccag tgaccgcttg ctaaaacaag
    13441 ctgatcgata gaatagcttt gctgatctgt ctgtaaaaga taaccatctt ttcttttgct
    13501 tacttttttt actaaagaat aaacaaactg aatagaagct ggaaattctt cttgcaactt
    13561 tgagaaaaac cagcgttgat agagtccgta taaacatcga gtagattgct gatctttttc
    13621 cagacgattg atttcttcta taattagttg cttatttttg gttaccgtct gttcgatata
    13681 atctgtagca ggtcctttac tccattgaaa caagttgggt ccctgtgtta ccaatcctcc
    13741 actggacaat gtttcatctg taaaaagcgt cacttgttga gaaacagaat tcattaataa
    13801 ctccggtggc tgattcaacc gccaaactcg acctccagga ccattgggat cgaaaagaaa
    13861 aagttcaaga gaatgtctgt cctgattatt atggagaatc ctttctgcta cacttaatcc
    13921 tctaggtccg gcaccaatga tccctatttt catttgcatg cctccatttc gataaatttt
    13981 ttcaataaaa cagcatggtt ctgatgttca ttttttgcac cataaacaaa agtaatgact
    14041 ggatgttctt tcataagttg actgagttta aaaatagctt gcttcttttc ttcttcgaaa
    14101 atcaattctt gctggtattt ctttgcaaat gaagcaaatc gttctggtac atggtcaaaa
    14161 gttttgcgtg cttcattact aggtgcaatt tctttcaacc acagatctaa ctgcgctttt
    14221 tcttttgaaa ttcctcgtgg ccagaatcta tccacgagta ttctatagcc atcctctttt
    14281 tcagcatcaa ggtaaacacg ttttaatttg atcatagttg tttccttctt tctacctttt
    14341 cgcttagctt atatatgtag ataatagcac aaaataaaaa aaatgaacgg cacaactatc
    14401 cattgcgccg ttcatgtgat cttggtcaaa atctaatgat tgattcggtt tttaaagctg
    14461 tcatacaatc atctgtttta tactttttta cttttgattt ttccagacca tccgtcatat
    14521 ccacccttaa gtaaataaat ctcttgataa cctgctttac gtaatttatt tgctgtacgg
    14581 atgctcaaac ttttcttttg atcgtaaata tagacaggct ggtcttttcg aatagatcct
    14641 aatgaatctt tcaaaacagt gtaagggatg tttcttgcac ctaaaatatg cccagcatca
    14701 aacacatctt tttcgcgaac atcgattact tgtgcttttc tcattccttc tcgaaattct
    14761 tcttctgtca aagtcgttgc tgaacgtttg gccattactc gtagatagac ttcccaaagg
    14821 atgattgcaa gcacaatcaa tagcaaaatg atattaatta cccataaaac catgtaatgc
    14881 ctccgttttt ttaagcaaat ttcaaggcta atgaggcagc accaatgaca ccagcttcat
    14941 taccaagctc tgctaatttg atttttgttg attctcttac ttgcgggaaa gtaaattctt
    15001 taaaatattt ctctacacgg ctacgtaaaa attctcctgc tgccgatact cctccaccta
    15061 acacgatact tgacggattt aatgtattcc ccaagtttcc gcaagctaaa cctaagtaga
    15121 agcatacgcg atcaacaacc atcaatgcaa acggatcgtc ttcttgagcc atttcaaaga
    15181 tatctttact tgttacttct tctccgttgt ctagcattgc tttcagtttt gaatcccctg
    15241 cgtattcttc tgccaagaaa cgacctaggc gtaccacacc tgtagcgcta gatacagttt
    15301 ctaaacatcc gcgtttaccg caagtacatt cgaacccttc aggatccaca gtgatatgtc
    15361 cgatttctcc tccagctccg ctcacgccgt gaatcaaatt tccgccagca acgatacctc
    15421 cgccaacacc tgttcctaga gtaacgaata caacgtctgg atcgttttct ccagcacctt
    15481 tccatcgttc acctaaagca gcaacattcg cgtcattatc gatagcgaat ttgattcctg
    15541 ttcctgcctc gatcagtttt ttcacaaatt gaacttctgt ccagtttaag ttatacgcac
    15601 caataaccgt tccagcttcg ctgtccacgc ttcctggggt acccatgccg attccgataa
    15661 agtcttcggc tttcatatta tataaattca aacgatgatt gattgattca atgatttcag
    15721 gaacgatatg cttaccatca tccaaaatat tggtatcgat gctccatttt tgctgaatct
    15781 ctccttctgg tgttaaaatt gcaaattttg ctgttgttcc acctaaatca atcccaataa
    15841 tcttcttgtc cattacaaat ttcctttctt tcggctttct tcaattcggt gctctctttt
    15901 taatatgcgc cacgctgtca tgtatgtatc atgatcaatc aaacggctat catacagatt
    15961 acgcaattcg atagtcatta attcaatgtc atagatgcgt gcacccacat agataaagat
    16021 gccaaatttt ttgaacagct gctgtacatc atataagctc tccatcttta agcacttcct
    16081 tcatattata caagtaaacc atattttttt aaacccagta aaatacatat tacaaaaaga
    16141 aatacaaaaa ctagtgtaga aagaatcctt tggtgtatcg aatagcttgt ctgttgtttc
    16201 ggtagaccca aaacattccc taacactaat ccgccaatta gcccaccgac atgtccccaa
    16261 acatctacag aggtatccag aagaccaaaa acaaatgtca acacaataaa taaaagaaaa
    16321 tgtctgacta gctgctggat cgctgggtta tgtttaaaat gaaaccctaa gataaacaac
    16381 gcaccgaaca aaccgaatat cgaagtactt gcaccaccag acagaacatt cgcttcgtta
    16441 aaagcaaagc ttgctgtatt tcccattatc ccgctgaaca tataaatcaa gaaaaaacgc
    16501 caatggccat agattgcctc gatttgctgc cccataaaat acagtatcag tgagttcatt
    16561 acgaaatgca tcagtccaaa atggatgaag attggtgtca ctaaacgcca ccattcattg
    16621 aagtgaacaa gataaggacc atacattccg gcataataag ggatctcaag tcgcggaaat
    16681 aattccatca tgaggaagac cgctgtctgt atccctaaaa aagcataggt ccataacggt
    16741 cgtcttaacc atgcacgcaa ttttatttgc tgttgataat tcatgaaaac ctcccatttc
    16801 attttagtca ataaacaatt gttggatctt ctgatcaaag ctctccggtt gccattgttc
    16861 attcaattgt tcacgaaaaa caaggctaca tgttttttta tgaaaattat ttaaataccg
    16921 gtcgtaataa ccaccgccaa aaccgattcg ataaccggct ctattgtaga taatacctgg
    16981 tacaatgagg agatcgatca tctccggcaa atagagcttc tctgattgtg gctcaagaac
    17041 accaaaactc gaacgtacaa gaacggactg ttcatccatt tcataaaacg ccatctgacg
    17101 tttcggcaaa gttttaggta caactatttt cttttgttct ttttctgctc gttggataac
    17161 cggctgtgta tccagttcaa attcattcga taaagtcgtc cctatcactt ttgctgactt
    17221 ccagtactcg ctggcgaata gctgtttata gattcgctgt tctttttcct ttttcttgcc
    17281 acttttggcc agatttttca gcttttcgat tcctttccgg cgtaatctta ctttcaattg
    17341 gtccaaaaac tcacccttcc ttctctcata aaatggtata ggaaaaaaag aaaaatagca
    17401 atcgaacttt caaataaatg cataaataga ataaaaagaa gacctagaaa tgattggcct
    17461 tcctttttta atgaatttca actgttcagc gcgtgttttt gtctgataaa aagtgcatac
    17521 agaaaatatg gcgcaccaaa aagggcaatc aaaattcctg taggtacttc cccacttagt
    17581 agaatcactc tagcaaccat atctgcacta agcagaaaaa tggaaccgaa caaaccgctc
    17641 agaacaaagg tccagttatt ttctttacgt acgactagct tcgcagcatg aggagctagt
    17701 agtcctacaa aagataaact acctgtcacc gctacactac cgcttgccaa agcaacagct
    17761 aacaacaaaa ggattttttg acttttagcc acgttaaggc ctaatccttg cgcgcgttct
    17821 tgaccaaatg atagcaatac aatcctctgt gcataaagtc ctcctagcgg aattaagata
    17881 accgcccatg gaagcaatgc ccaaacataa ggccagctcg caccccagat tgatcccgct
    17941 aaccatgcat tcacaaatcc ataattttcc ttagataatt ggatcgtgca tagcaatgtt
    18001 aatgcagaaa ggccggcatt aacggcaata ccggacaata agattcgatt catacccaaa
    18061 aagccatttc gatcataggc cgcaagatag acacagcaag cagctaaaac accacctaga
    18121 aaggctacaa ctagcaatag aaacggcagc gaatagtgcg aaaagaaacc taaataaagc
    18181 atcactaaaa atcctgctcc ggcattaatg cccaatatac tagaatctgc caattcattt
    18241 cttgttactc cttgcaagat ataaccagaa acgccaagac aagctcctgc taataaactg
    18301 atcagtaatc gaggaactcg aaattctcta acaatcagcg ccaaagaaga tgattctttc
    18361 cctatgaacg tggcaaaaag ctgatccagg taaataaaag gcgtaccaat cattaaacta
    18421 cctatagaca ggatgacaag tacaaaaagc aagaaataga acgtccaata tatttttttc
    18481 accgttgttc cctccttact tgtatcagta aaaacggaac gccaatcaat gcaatgacta
    18541 atccaaaagg tgtttcaaaa gggggattga tcatcctcgc tgtaaaatcc gccaacataa
    18601 ccaatccacc gccaactaaa aaagagacag gtagaacata acgatagtcc gttccaacca
    18661 ttccgcgaac aactggcgga accaacagcc caataaatga aacaggtccg actaacgaaa
    18721 cggcaatggc tgctaacact gcaactagac agaaaacaat caaccgcgtt cgtttaggat
    18781 gacttccaag agctaatgca tgtgtttcac tcaaatgaat caaagatatt gcttttccta
    18841 atgaaaaaga aaccaaaaca gcaagtatat ataaaggaaa caatactgct aattgtttcc
    18901 atgtgatatt ggcagctccg cctacaaacc aaaaagcaag atcctgctgc agattaaaga
    18961 attgggtaag tgcttggctg atagcagtaa aaaaagaact aatagctacg ccagctaaaa
    19021 tcagctgtaa aggattcatg cccattttcg aaaactgcaa aaaaccaaat acgagcaaag
    19081 ttacagcaaa agaacctgcc aatgacatta gaaacacaga aaaatcagaa gctttaggcc
    19141 aaaaagcaaa actaagggcc attgccaacg aagcacccgc gttgattcct agtaagcctg
    19201 aatctgctaa aggatttctt gtcactcctt gcatcaatgc accgctcaat gcaaaacaac
    19261 tccctacaag aaatgctccc gccacacgag gcaaacgaat atttcgtatg atttggtgac
    19321 tttgttttga tctatcaaaa tcaaacaacg cctgccaaaa atctgctttt cccacagtcg
    19381 ctgcgccatt tgaaagagca acaaaaaaaa taatcaaaag aacaaaacag accaaaagca
    19441 ggagtctatt tttcttcata gtcctcataa ttgatcctcc tgctcttttg gcaacaaatc
    19501 ataggttaga aaaactggtt tatttgttct tggaagcgtg acaatcgttg catcaatctc
    19561 aaatattttt ttcatacact cttttgtgat cacttcttca ggtgtacctt ctgtgatcaa
    19621 cttaccgttt ttcattgcta ataaataatc tgaaaaacgt gaagcatgat taatgtcatg
    19681 aatcgacatc aagatcgttg tttgtttcat ttgattgatt tcagtcaata actgtaggat
    19741 ctctaattgg tgtgccggat ctaaaaatgt tgtcggttca tccaagatca agatatctgt
    19801 ttcctgagca agcgccatag cgatccagac acgctgggtt tgtccaccag acagcgttgc
    19861 gatatcccgc atacgaaatc cagctagacc tgtagcatcc aacgcccact cgattgcttc
    19921 atgatcttgc gtgtccatgc cactgaacag tttttgataa gggtatcgtc cgtaagatac
    19981 tacttcttct actgtcatac ctgtagggtg ttcactagtt tgtgctaata atgcaatttt
    20041 ttttgcaagt tcttttgaac tgtatgtaga gatatcagag ttattgacaa tgatctttcc
    20101 tgatttcaca ggtagtatac gggtaaaact tttcaataaa gtagattttc cacttccatt
    20161 tggcccaatc aaactagtga ttttcccttc aggaatcgta acagacatgt tttcaatgat
    20221 ttttttgttt tcgtagccgg ctgcaatgtc agctgctctt aatctcgtca tttcacccat
    20281 cctttcgctg aaaatcattc tcaattatga cgctgtttca acatttcgtc aagcgctact
    20341 ttcatatcta tagccaaatg aagcggttga cagcgttcga aatatcagga ataataacca
    20401 atgagaaaga ttctcaatta tgttaggagg aaagaaatga aattaaaaac aaaagtattc
    20461 acattatcta gcatattgct gctggctgga gtactgagcg cttgctcccc ctcttcagat
    20521 aaagaaacag ctacaactgc caattcgacg acttcatcca atagtactca tacagtcaca
    20581 gatacacttg gacataaagt agagattcca aacgcgccca aacggatcat cggcagttac
    20641 ttagaagact atctgattgc actaggggaa aaacctatcg cccagtggac tgttggcagt
    20701 ggttccattc aagattatct gcaagatgat ttaaaggatg tcccaacgat ttcttatgac
    20761 cttccttatg agaaagtgtt aagctttgag cctgatttgc tgttgatttc ttcttccgct
    20821 actgtcgaag gcgggaaata cgaacaatat agcaaaatcg cgccaactta tgttgtaaaa
    20881 aacggaacag atgtcacatg ggaagaacaa ctaaaagatg tcggcaaagc tttggcaaaa
    20941 gaaaaagagg cagaaaagat catttccgat tatcaaaaat ccatcaagaa aactcgagaa
    21001 gaactagcag ataaaatcga gaacaagaca gctgcagtgt tgtgggtgac caacaactca
    21061 gcctttatgg tcagcaaaaa tcggtcaagt ggaagaatcg tatacgacga tctggaattt
    21121 ggtgttcctg atctagtgga agaggtctcc aaaaaagcca cttctgactg gtctgctgtt
    21181 tcctctgaaa agctagctga attagatgct gactacatca tccttgtgaa cagtgacaaa
    21241 gatgctgcca tgttcaatga accaagctgg aagaatctta aagcagtgac agacaatcat
    21301 gtactgcaat tcggacctga atctagttgg ctatataacg gacctattgc cagtcaggaa
    21361 atggtcaatg atatcaaaga aaaactaaat tgattttaac taaaaaaagc atcttcacga
    21421 ttagtcgtga tatgcttttt ttcttattaa caaactagac gcatagattt tattcttctt
    21481 ttgaagcaac cctatttttt actctttccc atttttgaaa acgatgggca tatagatttt
    21541 cttgatccgt tatcccctca tactcctcta taagggcgaa gtctgaaaaa tcaatattcc
    21601 caatatacgt atcgccttca aacgtgctat cgatcaatgt tcgccagatc cgaccagtgt
    21661 aaggaagaag ttcttgaaaa atccgactac cacccgaaac atagatatct tctgagatcg
    21721 tttgactata cgacaaaagt tcatcgatcg aatgcattac ttccgcattt tctttcgtgc
    21781 gaaaatttgg ctgcgttgtc aacacgatga tatggcgata aggaagtgaa agatccccca
    21841 ttccttcata ggtctttctt cccatcacta aaattcgatc cattgtatgt tcgcgaaaga
    21901 aacgcatatc atttggcaat cgccatggta acaaaccatt tttgccgatc agaccatttt
    21961 tatcttgtgc ccacatggaa ataaacatat tatccgctcc ttatgatttt agatgttttg
    22021 agataaaaaa agtctcaatt ctttgaccag caaggaattg agaactttaa aaacattatt
    22081 ttgtttcacg gtgcaaagta actttgcgtt cgcgtgggca atatttttgt ttttccaaac
    22141 gatcaggatt gttacgtttg tttttgcttg ttagatagtt acgttcttta caagaagtac
    22201 actctaaagt gatgtttacg cgcatgtttt tccctcccat ttttacaaga atcctctaag
    22261 atgactctca gacttgatta tcttaccatg attttttcta gattgctagt gtttttcacg
    22321 attttgttaa gtaaaactac ttgacgataa atacaacggt tttacttctc aaacaaaatc
    22381 tttttctttt tgtataaata cccttacact tgtttatata gattatgttt tttaataaag
    22441 ggggatacta atatgccatg gaacatgaag gactttcctg catcaatgaa aaacttagat
    22501 aaattgacaa gaaaaaaagc aatcgacatc gcaaatgcat tattagatga agggtaccct
    22561 gataaccgtg cgatcccaat tgccattgat caagcaaaaa aatggtatga agatgctagt
    22621 gaatcagaaa aacgaacttt cgaaaaagaa aaaaatccaa gcaagacgga tgaacacgat
    22681 acgaatcctc gtgctggaaa actgcttgat tcagatgtga tcgtagaata tgaggaagaa
    22741 caatggatcg tgaaatctaa aggggcaaaa aaggcaagca accattttga tacaaaaaaa
    22801 gaagcaatcg aaaaaggaaa gcaagtagca caaaacaaag aatcaacttt gttcatttat
    22861 aaaaaagatg ggacaaaaga aaaagaaatc gattattgaa catatgtaaa ggggttgtga
    22921 cgaaaatcgt gtcacaaccc ccttatgttc gaaacaatgg tgttcctctg ccaactccga
    22981 accataagtc ataatatcta taaaacggga agagctgttt tttgaaattg tttcttatca
    23041 ctcagtgtta aacggtagga gaaaacctct tttttattga tatttgattt tcatcaaaca
    23101 gtcacatagt cgattgcttc tgcttgcgga atcgtttcat ctacaaagta gactttatac
    23161 catgtcaaga aactgaagat tgtccagatt tttctttgct cttctttacg tccttcgtga
    23221 tggtcatcta gcaacttcat gattttttct tgatcaaaaa attcttttgc aaaatctgct
    23281 tcgaacaatg ctttgacttg ttcgtagccg tgttcttctt tcaaccaagc tttgattggc
    23341 acagggaatc ctaatttcac acgattcgac catttttccg gaagatgttt gttcgcagct
    23401 tgtctgaaaa tatcttttgt gttgttttga ttcaataaaa acttacttgg tatttgttga
    23461 gccaatttca tgacttcgat atccaataaa ggtactcgga cttccaaaga acttgccata
    23521 gaaagtttat ctgcctttaa caagatatct tttggcatcc attgatgaag atcgacatat
    23581 tgcatcttat tgacttcatc tttgattcct tctgttttct cgtaatgaac agtcatgatt
    23641 tcatccacag atggtgctgt ttgatatttt ggtgttaaca cttctgatgc ttctgattct
    23701 tcgaacactc gagcatgacc gataaaatat tcttttgcag gagcaagtga ttcatataaa
    23761 tggatccgtc catggaaatt tttcattttt ccgattttac gtcctaaatt atagcgtgtt
    23821 ccttttggta attttttcaa tccttgagca atcacacgga tgaattttga attcgtatgg
    23881 aatccatacg tttggtatcc cgcaaacagt tcatccgccc cttctccaga ttggactacc
    23941 cgcacacttt gtgaagcaag atttgctaaa aagtacaaag gtacgcaaga aggatttgaa
    24001 tcaggttcat ctaagtgata ctggatcaaa gggaatgctt tgaacgacat gtctccgtcg
    24061 atcactgctg ctgtattatc taagtccaat agttcggtta gttttctggc ttcaatcgtt
    24121 tcattatagg ttttatcatc aaacccgatt gagaaagaat gatctggttt caatacagag
    24181 gttacataac tggaatcaac cccgctggat aagaaagaac caacttctac atcactgacc
    24241 gtatgtgctt caatagaagc ttgaacggtt tcgtcgattt tttcgatcca ttcttgtcgg
    24301 gaatgcgttt cttttgtttc aaaatctgca tcccaatatt gctgaatgtc tatttttcca
    24361 tctttatacg tataataatg gccttcaggc aaacgataga catctttgaa gaatgtttcg
    24421 ccgtttaatg gagaatattg gaaagtcata taaggtttca acgcttcttt gttcaattct
    24481 ttgttaaaat caggatgagg cagaaaactt ttgatttctg aaccaaacat aaatgttccg
    24541 ttcatttctg cataataata tggtttgatc ccaaagtggt ctcttgcacc gaataactca
    24601 ttcttttcat tatcccaaat agcaaaagca aacattccgc ggatcttttg caataattct
    24661 gttccccatt cttcgtaacc atgcaaaagg acttctgtat ctgcatgtgt ttgaaaaacg
    24721 tggccagctg caatcaattc ttctctcaaa ggctggtaat tatagatttc gccattaaaa
    24781 ataatgatct ttgtccgatc ttcattgtaa ataggctgag taccgccctc taagtcaata
    24841 atacttaatc ttctgaatcc taaagcaaca tgtttatcga tatattctcc tgaactatta
    24901 ggtccacggt gaacgattcg atccatcatt gtattaataa ttgttttttt gttgtccttg
    24961 tcgttaacaa aacctacaat accgcacatt taactttcac atcctaatat aaaattactg
    25021 tttatttcat tcatatgcat cttatcatag aataaatagc ggacgaatat tttctctctt
    25081 acaatttcgt cacgtgaaaa caaaagatga aagtttctgt ttttacagaa aataaagtcc
    25141 caatatctaa tttaccatgt tttctttttt gaggctacct tattctcttc gtgttaaaaa
    25201 aatattagtg gatgctattt ccaaaaaaac cagcaaaaaa agacacgacc taaagatcgt
    25261 gtctaattat gactgtatca gaaaatatga taccaaacgg atctattcat taattaattg
    25321 acatagttta tctgttgctc ttttatgact ggataactga ccaattcatg acgatccaag
    25381 tcttctttat tcatatttac agcagtaatt tgactgtctt catacgtacg ataataataa
    25441 atccctttat caacgttaca gcaagaagaa taaatcgtat attcgtattt tctttctcca
    25501 gtatcgcata ctcctttttg ttgctcgact gagcctagta tatgaaaaaa ttgactgata
    25561 ctttcagatt ctgaatcacc tgatgcagca ttcattttag taaatgtggc ttttacaaat
    25621 cgagaaacag aagagagatc tccaggtaag cccaatcctc ccatcccacg actataaaca
    25681 ttcaagctga tctggtttga aaaatgattt tctggtgttc catttgatag cgagcgataa
    25741 ttgttcagat taaataattg ataatcaaat ggcggattat ttgtcaacac accgacagga
    25801 ttatcatata aatgaagtcc atctttcata ctttcaatta ctatcgattt ttctttatca
    25861 gctaataacc agtgtaaagg tgacaagggt agtttttcac taaaatcgat attgactaga
    25921 ttgatagtag ccaataattc tttagcttcg tctatggttg agcattgccc tagtatccat
    25981 ggaataaact caaatggtgc aacgttatct tttccttctt gtaattcttt ataatcagca
    26041 ttgccaggaa aattcagtcc tgccatactc aacccttttt catttgtagc ctcataatag
    26101 agtggatagt tggatacccc agctgctatt cctatcattg cataatgttt atctaaattt
    26161 tttacctttc taaaatcgaa acgataattt cttggagtaa tagtgaccac ttcattataa
    26221 gacatctcat aatcaaaatt ccttccaaaa taatggtctt tcgttgcata agtgattgcg
    26281 gtacacatcg tttcccgtcc taaaacaaat cgtttttaca cttttatctt acatctagta
    26341 ttttttttat caaaaaaagg ccaaagaaga ttgatttact agcatttata aaaaatagta
    26401 ctcaggggga atcaaaaaat att
//
LOCUS       DAFBVQ010000036        26027 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.036, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000036 DAFBVQ010000000
VERSION     DAFBVQ010000036.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 26027)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 26027)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..26027
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.036"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(43..681)
                     /gene="plsY"
                     /locus_tag="LLC22_001687"
     CDS             complement(43..681)
                     /gene="plsY"
                     /locus_tag="LLC22_001687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerol-3-phosphate 1-O-acyltransferase PlsY"
                     /protein_id="HBK5434969.1"
                     /translation="MKLILLLILAYLLGSIPSGVWIGKLFFKKDIRQHGSGNTGTTNT
                     FRVLGKTAGIVVLLMDILKGTLATCLPMIFHLSGINPLWFGVCAILGHTFPIFAGFKG
                     GKAVATSAGMLLGFNPVFFVYSCIIFIVSLFCTSMVSLSSMISAVLITLSTIVLPYVA
                     PVILAKPNWLLTIIAFLVSSFIFYRHKDNIKRIRNHTESRIPFGLNSSKKKS"
     gene            808..1242
                     /locus_tag="LLC22_001688"
     CDS             808..1242
                     /locus_tag="LLC22_001688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330223.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CoA-binding protein"
                     /protein_id="HBK5434970.1"
                     /translation="MSVKNPTQETIFNYLEEAKNIAVVGLSNKPERTSYMVAQVLQDN
                     GYKIIPVNPLLAGEEILGEKVYANLTEIDDPIDIVDVFRRSEFLPEIAGDFLKTDAKV
                     FWAQLGIENKEAAEMLRKAGRTDIVMDRCIKIELGKLKENQK"
     gene            1408..3453
                     /gene="parE"
                     /locus_tag="LLC22_001689"
     CDS             1408..3453
                     /gene="parE"
                     /locus_tag="LLC22_001689"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331043.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit B"
                     /protein_id="HBK5434971.1"
                     /translation="MAKKVNNEYNDSSIQVLEGLEAVRKRPGMYIGSTDSRGLHHLVY
                     EIVDNAVDEALSGYGSEIDVTIHEDNSITVADSGRGMPVGMHASGIPTVEVIFTVLHA
                     GGKFGQGGYKTSGGLHGVGASVVNALSKWLIVTIVRDGVEYQQKFKNGGKPDGTLKKI
                     GKTKKANGTTVHFLPDDTIFSTTKFSYEILAERLRESAFLLKGVKISLSDLRGEEPVK
                     EIFHYEEGIKEFVDYLNEEKDTLTPVVYFSGEKEGIEVEVAYQYNDGYSENVLSFVNN
                     VRTKDGGTHEAGMKAAMTKSYNEYARKVGLLKERDKNLEGSDFREGLAAVLSIRVPEN
                     LLQFEGQTKEKLGTPVARTVVDNVISEQMGFYLQENSEMSQMLVRKAIKAREAREAAR
                     KAREESRNGKKRKKGESLLSGKLTPAQSRNPKKNELYLVEGDSAGGSAKQGRDRKFQA
                     ILPLRGKVINTEKAKMQDILKNEEINTMIYTIGAGVGPEFSIEDCNYDKVIIMTDADT
                     DGAHIQVLLLTFFYRYMKPLIEAGKVYIALPPLYKVSKGQGKKQVIEYAWTDDELAAM
                     IKKVGKGYMLQRYKGLGEMNAEQLWETTMDPTSRTLIRVRIDDAAQAERRVTTLMGDK
                     VEPRRKWIENHVQFTLEEDGSILDKKEDTEISPSVSNDLLDEERADKNENNQLFEVE"
     gene            3465..5915
                     /gene="parC"
                     /locus_tag="LLC22_001690"
     CDS             3465..5915
                     /gene="parC"
                     /locus_tag="LLC22_001690"
                     /EC_number="5.6.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase IV subunit A"
                     /protein_id="HBK5434972.1"
                     /translation="MENRQEVQELTLEEVMGDRFGRYSKYIIQERALPDIRDGLKPVQ
                     RRILFAMNKDGNTYDKGFRKSAKSVGNIMGNYHPHGDRSIYEAMVRMSQDWKLREVLI
                     EMHGNNGSMDGDPPAAMRYTEARLSKLSGEMLADIEKETVDLVWNFDDTEKEPTVLPA
                     RYPNLLVNGSTGISAGYATEIPTHNLAEVIDGTIYMIDHPQASLEKLMEYIPGPDFPT
                     GGILQGKDEIKKAYETGRGKVILRSKTKIEAMKGNKQQIVITEIPYEVNKATLVKKMD
                     EIRLNKKIDGIAEVRDESDRTGLQIVVELKKDANAQGILNYLFKNTELQINYNFNMVA
                     IDHMTPHQVGLKDILRSYIEHRKQVITKRSQFDLAKAQKRQHIVEGLMKALSILDEVI
                     ATIRESKDKKDAKKNLVDVFQFTEEQAEAIVTLQLYRLTNTDITELQKESESLIAQIT
                     ELNKILSNDKELFSVMKKELREVKKNYSSARLTTIEDEIEEIKIDTQVLVAQEDVIVS
                     VTREGYVKRTSLRSYSASKPEEIGMREGDYLLYSGELSTLDHVLLITNKANVIYRPVH
                     ELPDLKWKDAGEHISQTISNLSVDESILAVFPYQKIQAEKTFVFISKNGLIKQTRMTE
                     FEPWRTYKSRPLSCMKLKAEEDELIAVYLKEDQPGLDVFLVTHQGMGLRYPLTDVPVV
                     GAKAAGVKSMNLKDGDRIINGLLVLAEGDTPIVIVTQRGAVKRMLAQEISQTSRAKRG
                     VTVMRELKKNPHRIIYMSEGRSKEITLMNQKGQQLTIDPTDFPIGDRTSNGSFAMDEK
                     KGGEVIEVIDAPEIFIES"
     gene            6192..8423
                     /gene="pflB"
                     /locus_tag="LLC22_001691"
     CDS             6192..8423
                     /gene="pflB"
                     /locus_tag="LLC22_001691"
                     /EC_number="2.3.1.54"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate C-acetyltransferase"
                     /protein_id="HBK5434973.1"
                     /translation="MEQWNGFKGTKWKEGVDTRDFIQNNYTEYRGDDSFLEGPTEATE
                     KLWDELQKLNDIQFERNGVYDMDTEIVSTITSHDAGYLDKDLEKIVGLQTDKPLKQAF
                     MPFGGINMANNALKSNGYTPNDELTHIFTDWRKTHNQGVFDAYTAEMRAARKNKIITG
                     LPDAYGRGRIIGDYRRVALYGIDYLMEQKKKDHDMTGYHTMSEEVIRLREEITEQYRA
                     LAQMKEMAAKYGYDISKPAANAKEAVQWLYFGYLAAIKSQNGAAMSIGRISAFLDIYI
                     QRDLDNGVITEKEAQELIDHLVMKLRMVKFARTPEYNQLFSGFPIWATLSIAGMGLDG
                     RSLVTKNDFRLLHTLTNMGPSPEPNLTVLYSEHLPEGFRTYASRIAIESSSIQFENDN
                     QLREQWGSDDCAIACCVSGTVVGKDMQFFGARANLAKTLLYAINGGVDEVTGAQVGPE
                     YRPITSEILDFEEVKHNFMNMMDWLAELYVNTLNIIHYMHDKYSYEAAQLALMDSDLQ
                     RTFATGIAGISHAADSLSAIKYAKVKAIRNEKGIAVDFEVDGDFPKYGNDDDRADELV
                     SWILEYFMGQIKRHKTYRNSKPTTSLLTITSNVVYGKNTGNTPDGREAGKPLAPGANP
                     SYNAEQSGLLASLNSTAKMNYGCALDGISNTQTINPSGLGKEQDTRIENLRNVLDGYF
                     SKGAYHLNVNVFSNDLLRDAMENPMKYPNLTIRVSGYAVKFRDLTREQQLDVLMRTSH
                     DRM"
     gene            8667..9428
                     /gene="pflA"
                     /locus_tag="LLC22_001692"
     CDS             8667..9428
                     /gene="pflA"
                     /locus_tag="LLC22_001692"
                     /EC_number="1.97.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate formate lyase-activating protein"
                     /protein_id="HBK5434974.1"
                     /translation="MEEKTIGYVHSIETFGSVDGPGLRFVVFMQGCRMRCQFCHNPDT
                     WNIGGGKEYTADELLDKAERFRPYWGDKGGITVSGGEPLLQIDFLIELFKKAKERKMH
                     TTLDTCGKPFTYEEPFFSRFQELMKYTDLLLFDIKHIDNEEHKKLTHWDNENILEMAQ
                     YLSKINKPVWIRHVLVPERSDYDEYLIRLDNFIQTLSNVDRVEILPYHTMGKYKWETL
                     GLKYPLEGIEPPTKERVENAKRLLHTEEYTKYLTR"
     gene            9513..10439
                     /locus_tag="LLC22_001693"
     CDS             9513..10439
                     /locus_tag="LLC22_001693"
                     /EC_number="3.6.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="manganese-dependent inorganic pyrophosphatase"
                     /protein_id="HBK5434975.1"
                     /translation="MSKILVFGHQNPDTDAIGAAIAFSHLQNELGKETEAVALGTPNE
                     ETQYALDHFQLSAPRVVESAKAENADVMLVDHNEFQQSISDISEVNILAVVDHHRIAN
                     FETANPLYYRAEPVGCTSTIILKLYKENQVTIPKEIAGIMLSAIISDTLLFKSPTCTP
                     EDEAAAKELAAIAEVDLNTYGLEMLKAGTNLSDKSAAVLLDLDAKSFPMGSSNVRIAQ
                     VNTVDLNEVMDRQAELEAAMEDEMKANGYDLFVLVVTNILDSDSELLVAGKGKEKVEE
                     AFQTTLTNNRALLKGVVSRKKQVVPQLTAVFS"
     gene            10621..11514
                     /locus_tag="LLC22_001694"
     CDS             10621..11514
                     /locus_tag="LLC22_001694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1803 domain-containing protein"
                     /protein_id="HBK5434976.1"
                     /translation="MNYYSKNKENFYQKLTDDPLFSSLTDYLYEHREQETILRELKKE
                     FSQNKFSHFLDLLIDAGLIKREERRYHLNFPIFDPKDYLQQATSAAETIAEQLKRLSV
                     DEQKLAMGEVIWAYCFEDERKEAYFYGVRNSRETELLRTTAGNEKYRFITLSSIEHFP
                     LTLANYFFVQKNQLPVTKAFKELAELIGDVNESYFFDQIEVIVDRIRKNKYKNRRPSI
                     FHQSLLVTNTIKEEESFTLELPIVEKNNFEIELPTLDPSLTMEEMAFLKRQIFSELSK
                     KFIPHAFSYIKEYGTVLVSKT"
     gene            11648..11773
                     /locus_tag="LLC22_001695"
     CDS             11648..11773
                     /locus_tag="LLC22_001695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5434977.1"
                     /translation="MQKNGEKCGMTKEVVIRKVRFLNNQYYDSVKYGILWEELAD"
     gene            complement(11907..12539)
                     /locus_tag="LLC22_001696"
     CDS             complement(11907..12539)
                     /locus_tag="LLC22_001696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345061.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434978.1"
                     /translation="MEIQRRTTNFLHLGSFFATLTILFFLCYSYLKTSHAPSSALGWL
                     LLDHSDITEAEENPFFLILSSLCGLLFSVYFGAYFFHRHPGTLNEASSVLIAFKTFSF
                     LAILFYSFNHNTLFFFIMNGLVVILSIFTYFIFSLIFSQLKCPLFFRLVPVTCFIYSL
                     FSFFVLALMPLTNPSTIQVAGNLLDMLFIVSLGVFMWQRKNKQNKKHFEA"
     gene            complement(12687..13229)
                     /locus_tag="LLC22_001697"
     CDS             complement(12687..13229)
                     /locus_tag="LLC22_001697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2179 domain-containing protein"
                     /protein_id="HBK5434979.1"
                     /translation="MIDPKMLGMIFLINFAYITLNTLRFMLTMKGYRLIAPLVSMVEI
                     TIYIVGLSLVLDRLDNPLNLFVYALGYAVGISVGILIEDKLALGYIMVTTILPANSAE
                     DKSLPGILREHGYGVTQTSAMGLEGERLVLEILSPRKSERELYRLIKEIEERAFIISY
                     EPKYISGGFWTKKVRKRQGK"
     gene            13364..13753
                     /locus_tag="LLC22_001698"
     CDS             13364..13753
                     /locus_tag="LLC22_001698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434980.1"
                     /translation="MKTVNRVFCASHVLSLLLSIYLGVYSIQQPIEVENIVFQMSLTD
                     GLILSVFFFLILFIGNIFGSVASFLNFSIYPLLSLALGVVGLCSLCLFPEPFSPAFIL
                     FGTLNLFQTTVGAWLLWRSGNLMKIGE"
     gene            13757..14521
                     /locus_tag="LLC22_001699"
     CDS             13757..14521
                     /locus_tag="LLC22_001699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264666.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5434981.1"
                     /translation="MNPIILKRSVHHIPVLEVVLKELREERIPVVIYYHGWQTSKELV
                     LTQGRKIAQQGIRVILPDAMNHGERKQPVSSIPSYTFWDSIYGNLFEFDTLIKHLEKR
                     GLLHDQLAVGGVSMGGMTTCALLAKHPHIVAGVCLMGSPAPLEYGKEIVRRASEYNYV
                     VPKDYFDLISWVKSYDLSLQPEKLAGRPLFFWHGQAGEKIPYIQTERFVEKNRHKSYG
                     KEIVFRSSKTQRHMVQIPLMEEASTFLAKNLIKKYK"
     gene            14650..15597
                     /locus_tag="LLC22_001700"
     CDS             14650..15597
                     /locus_tag="LLC22_001700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5434982.1"
                     /translation="MPTLADVAKRANVSKMTVSRVINHPEQVTDELKELVFSAMAELD
                     YRPNIAAKALVTNRSQIIKLFILEEIDTTEPYYMNLLMGIAKRIGKAHYSLQLVTNDA
                     FDVGSCDGYIITGVRKKDFDWIDRLEKPVVLFGENSEGYDYVDSDNEYGTAKATQYAL
                     ERDYQTIIYIGIEVDEPFEISRETGYLSVMKEVDLPSKILRFPNHSTEVERYMTENWA
                     DFTDKTCFVCSSDRLALGAVRGIINAGGHLPEEFGVIGFDGVFLDQISSPKLTTIKQD
                     IIRMGEVCGEMLLKKIEEKGASQGYRRFFPELVIRETTN"
     gene            15727..16467
                     /locus_tag="LLC22_001701"
     CDS             15727..16467
                     /locus_tag="LLC22_001701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434983.1"
                     /translation="MKEIRRKHFRFPAYDDELGVKLTNDKKRVLFDGQEDLLTEQNQS
                     PFEQMKEFHFTNTNTEKIRRKRRATNGLKSAPRKENLEKHKGKLPDYTGHYQSEITST
                     GRKKLFGDSSRSVRQSETRTESKHTTRNASVDTKVRERSYFVPKYVPASIIPDPRESK
                     ISEDHLIESMKKTDDSYLLFDTEPTPYQEKRNGEPSVRTFNRTKTLEETKQSEEKKSK
                     KSHGILERSLQGLIDDQGNSLGENSYFK"
     gene            complement(16758..17426)
                     /locus_tag="LLC22_001702"
     CDS             complement(16758..17426)
                     /locus_tag="LLC22_001702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328585.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5434984.1"
                     /translation="MKKLNLFTELCGIILGAGIYGLAVTGINIPSKLADGGVTGIALL
                     LHNLFGFAPSVTSLLFNLPLLLISLFLFGKHAFLRTIVGTFALVFFLHLWESLHIHFA
                     VDSLLINSLMTGILSGIGCGLVFRFGGSTGGTDIIYQAIEKYFHIKIGKSLFLITFGI
                     LVVSLLYLDLTHFLYTLLSCSILSYTLNKVKYLEIGSVLPQLEAKQTTETFEPLDPLE
                     QLEH"
     gene            17560..17847
                     /locus_tag="LLC22_001703"
     CDS             17560..17847
                     /locus_tag="LLC22_001703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434985.1"
                     /translation="MRAADLLTILTKSPKKTEYQGVFLAQEQKLVPVTMVQINKANQF
                     IFLFEHGKAPLAMKDIFLFLMKNREKAVYYQSKEELIPLYGVKEIENKVVI"
     gene            18263..19801
                     /locus_tag="LLC22_001704"
     CDS             18263..19801
                     /locus_tag="LLC22_001704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306907.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate-binding
                     protein"
                     /protein_id="HBK5434986.1"
                     /translation="MNNFIQTLSERKGELLEAAFQHLSISLISLLIAALIAIPLAIWA
                     ANHKKMAEVLLQITGVLQTIPSLALLGLLIPFVGIGTVPALIALVIYALLPIFQNTYI
                     GLAEIDPSIEEAAVAFGMSRMRRLLKVELPIALPVIISGIRTALVLIIGTATLAALIG
                     AGGLGTFILLGIDRNTPVLTLIGAISSALLAIIFSGLIRWLQHKKPRYSIITLAAVVC
                     LFGGVSLYQSALFKNETITIAGKLGAEPEILIQMYKELIEDNTKTEVELKPNFGKTSF
                     LFNALDQGQIDIYPEFTGTVLESLVKVPEAMKSADLTKEKTYDEAEELLNKQFDMTLL
                     KPMAYQNTYALAVKRSFANEHQLKKISDLAAISDQIKAGFTLEFIDRSDGYKGIQEAY
                     GLNFSSVQSMEPSLRYQAINNGDVNIVDAYSTDSQLKEYDLVTLEDDRGLFPAYQGAP
                     LMKKDFAKEHPEIVKALNKLSGKITEDQMIDMNYQVNVEKKKPTEVARIFLKNEGLVK
                     EEDQ"
     gene            19798..20763
                     /locus_tag="LLC22_001705"
     CDS             19798..20763
                     /locus_tag="LLC22_001705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434987.1"
                     /translation="MTKLIEFKHVQKKYDGKYVIDDLNLAIKKGEIFVLVGPSGSGKT
                     TTLKMINGLSKPSAGDIYFKGKSLNEYNLQKMRWNMGYVLQQIALFPTMTVKQNIEVI
                     PEMLGWEKQKRADRVDELLQKVGLSPDIYRDRMPRELSGGEQQRIGIIRAIAASPDVI
                     LMDEPFSALDPISRNSLQELVLSLHEELGTTIVFVTHNMEEAIKLGDRIAFMKDGEII
                     QCDTPEQLLMNPKNDYVRHFFDEPKQTKEWRVEDLVVNGYFLNEIPENARQQVCFDTP
                     MKEVYSLLSVYPSIVIVEKQRSIGSLTSKEIFAFLSREEEGNENI"
     gene            20750..22072
                     /locus_tag="LLC22_001706"
     CDS             20750..22072
                     /locus_tag="LLC22_001706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5434988.1"
                     /translation="MKTYDAIIIGSGVSGLSAAYGLKEAGKTVLVVEEDLWGGTCPNR
                     GCDPKKVLLSAVEARNRVKQLSGKGFNEIPTANWEELQKFKRTFTDPVPESRKKQLAE
                     AEIDHLSGTARFLDDSSIEVNEEVFHADYLVLATGQRPTILPVEGKEYLKTSADFLSL
                     PVLPKEIIFIGGGYIAFELATIANAAGSKVTIVHHNQRPLKEFEASLVEEAVHQMEAS
                     GIQFAFGVETQKIISEGTRYRLVGKETELVADMIFCATGRQPNTESLALEQANIVFDK
                     HGIAVNDYLQTSNPKIFACGDIVSRKTPKLTPVATFEGNYVAKRITDATSEPIKYPII
                     PTIVYASPKLAEVGVTKSHASSSDQVVEMDLTSWFTYHRVNEPVAKAELTFDQQNYLI
                     GAAVISEQADELIDDLTLVINQKLTKKELDSYIMGYPTLASDLSYLLK"
     regulatory      22135..22239
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00059"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="TPP riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="thiamine pyrophosphate"
                     /db_xref="RFAM:RF00059"
     gene            22313..23056
                     /locus_tag="LLC22_001707"
     CDS             22313..23056
                     /locus_tag="LLC22_001707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5434989.1"
                     /translation="MKKNLYPAVSMAFILIIWQIVVIVWKIPAFILPGPAAVFSALAA
                     DAQVLLSHSVTTLNEAVLGLVIASVLSFITALAMDYWKFLEMSFYPLLVISQMLPIMV
                     LGPLLTLWFGFGMLPKVILVVLISYFPIVVSFSDTLRKVSKEQIIFLKTMGADTGKIY
                     RIYKIPAGLSGFFSGLKVAATYCVSGAVVGEWLSAQAGLGYYMIRVKNSYQIDKVFAA
                     IICVILLSLLLNGACSLLKKGYYRMLYIF"
     gene            23071..24063
                     /locus_tag="LLC22_001708"
     CDS             23071..24063
                     /locus_tag="LLC22_001708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter substrate-binding protein"
                     /protein_id="HBK5434990.1"
                     /translation="MKKLWLLLPLLLLLSACGTAKETSSKQEIKDLKKVTLVLDYVPN
                     TNHTGIYLAKEKGYYKEAGLNVQIIEPGDNSTSIGLVGADKAQFGVSYQEDVTYAHAD
                     GQNIPVKAIATVIKHNTSGFATLSDSNIHSPKDFEGKTYAGWQSPSEEAVLKAVMEKD
                     GGDFSKLTMVGSNGEGPESLGKSSDIQWYFEGWDMIKAKEAGIELNYIPLKELDERLD
                     YYTPVIITNDQLIKSDPELVQSFMDATKKGYQEAIKDPNDSAKLLQKYAKENDRTFLE
                     ESQAFLSKNYTDDPENWGLMEEKVWRNYTAFMQENGLIKQDVPSQELFTNQFIK"
     gene            24075..24812
                     /locus_tag="LLC22_001709"
     CDS             24075..24812
                     /locus_tag="LLC22_001709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390764.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434991.1"
                     /translation="MSIQISHLNVVIENLKILEDIHFTIPKDTFTSIVAPSGAGKSTL
                     LKTLTGVQPMTSGTIKVDDQKVTGLHTAFSYMPQEDMLLPWLSVYQNVTLYQKINHLT
                     INEEQVRDYLDIFGLNGYEHFLPEQLSGGMKQRTALLRTIMNPSSYLLLDEPFGALDA
                     MTRGQMQDWMLKLPKKAKRTTLLVTHDIEEAIYLSDRILVLSARPAHVIAEIQVPEKR
                     RSREWLLQQSELKQTIYQLLAGELDVK"
     gene            24802..25524
                     /locus_tag="LLC22_001710"
     CDS             24802..25524
                     /locus_tag="LLC22_001710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TatD family hydrolase"
                     /protein_id="HBK5434992.1"
                     /translation="MLSDAHCHLDGSQSLALLQQEHTILTIINCDSPEEWKENRQLAA
                     SKTQALSYGIHPWKADSYTFEQVEPFLKKARIIGEIGLDNIWTNVPMTTQKKVFERQL
                     AFAAINEKPVVLHTKGCEKEILNYIQAYPNHYLIHWYSSLDYQQDYIDLGCYFSIGLD
                     LKKNPAVWQLAKAVPIDHLLIETDGLHAAEWALGGIFSEKDYVSLLEEQLKTIAEIKE
                     LSVEEVKKNTYQNLERFIRLGK"
     gene            complement(25608..>26027)
                     /locus_tag="LLC22_001711"
     CDS             complement(25608..>26027)
                     /locus_tag="LLC22_001711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase M23"
                     /protein_id="HBK5434993.1"
                     /translation="YSGQQLTIPTEGSAQAAAEPQAAVQEAPVQAEQPVVQETVQTEK
                     QAAPVAETQPAPAVTETAATPASTSSAKEWIAQKESSGSYTATNGRYIGRYQLDSSYL
                     NGDYSAANQERVAEQYVTSRYGSWEAAKAFWEANGWY"
BASE COUNT         8953 a         4426 c         5429 g         7219 t
ORIGIN      
        1 atttgtcaca ctcccgtttt atctctttgg aatgaaaaag tatcaggatt ttttcttgct
       61 gctattcaaa ccaaacggga ttcgactttc agtatggttt ctgatacgct tgatattgtc
      121 tttatgccga taaaagataa aggaagaaac taaaaaggca atgatcgtca gtaaccaatt
      181 gggcttagcc aaaatcacag gagctacata aggaaggacg atcgtagata aagtgatcaa
      241 tactgcactg atcatactgc tcaaactcac catacttgta caaaataaac taacgataaa
      301 gatgatacaa gaataaacaa aaaatacagg attaaatcct aaaagcattc ctgcacttgt
      361 cgcaacagct tttcctcctt tgaacccagc aaaaatcgga aatgtatggc caagaatggc
      421 gcatacccca aaccaaagag ggttaatccc agaaaggtgg aagatcatcg gcaaacaagt
      481 agccaatgta ccttttaaaa tatccataag caggacaaca atcccggctg ttttgcctaa
      541 tacacgaaat gtattggtcg ttccagtatt accgctcccg tgttgtcgga tatctttttt
      601 gaaaaacaat ttgccaatcc agacaccgga aggaatagaa cctaaaagat atgctaaaat
      661 aagtaataag atcaatttca ttttttaccc tctttcaagt tgaaaactat cctttatttt
      721 agcatgaata ggtaacagga acaattgaaa aaatgaaaga tacaagtata atagatggaa
      781 taaaaagaaa agcaaggggt ggcagaaatg tctgtaaaaa atccaacaca agaaacgatt
      841 ttcaactatt tggaagaagc aaaaaatatt gccgtcgtag gcttgagcaa taaaccagaa
      901 cgaacaagtt acatggttgc acaggtattg caagacaatg gatataaaat cataccagta
      961 aatccattat tggctggtga agaaattcta ggcgagaaag tctatgcgaa tttgacagaa
     1021 atcgatgatc caatcgatat cgtagatgta tttagacgga gtgaattttt acctgaaata
     1081 gcaggtgatt ttttgaaaac tgatgctaaa gtgttctggg cacaattagg gattgaaaac
     1141 aaagaagcag ctgagatgct aagaaaagca ggacgtacag atatcgtaat ggatcgttgt
     1201 attaagattg aacttggtaa gttgaaagaa aaccaaaaat aaaaatgacc acaaagaaga
     1261 gatgatcgat agaggggaat gtcgaaaaag cggttaggag ataattaaaa ttgatttctc
     1321 gtctaccctc ttttttttca cgaccttttc tagtatgata atcgtggtgc ggttttgccg
     1381 caaagtatta ttgaaggagc gtttgccttg gcaaaaaaag taaacaacga atacaatgac
     1441 tcgtccatcc aagtattgga aggattagag gcagttagaa aaagaccagg gatgtacatt
     1501 ggatccactg acagccgagg cttgcatcat ttagtctatg aaatcgtcga taatgcagtt
     1561 gacgaagcat tatcaggtta tggcagtgag attgatgtga ccatccatga agacaatagt
     1621 ataactgttg cagatagcgg acgtgggatg cctgtaggaa tgcatgcttc cggaatacca
     1681 acagttgaag tgatttttac tgtgctgcat gctggcggaa agtttggtca aggagggtac
     1741 aaaacttctg gtggactgca cggtgtagga gccagtgtgg taaatgcctt atcgaaatgg
     1801 ctaattgtaa cgatcgttag agatggcgta gagtatcagc agaaatttaa aaacggcggt
     1861 aaacctgacg gtactttgaa aaagatagga aaaacaaaaa aagcaaacgg gacgactgtc
     1921 cattttttac cagatgatac aatattcagt acaacgaaat tttcatatga aattttagcc
     1981 gaacggttaa gagaatctgc ctttcttcta aaaggcgtta aaatctctct ttctgatctt
     2041 cgtggagaag aaccagtcaa ggaaattttt cattacgaag aaggaatcaa agaatttgtt
     2101 gattatctga atgaagaaaa agatacattg acaccagttg tttatttttc aggagaaaaa
     2161 gaaggtatcg aagtagaggt cgcttatcaa tacaatgacg gttattcaga aaatgtttta
     2221 tcttttgtca ataacgttcg gacaaaagat gggggaaccc atgaagctgg tatgaaagcg
     2281 gcgatgacga aatcttataa tgaatatgcg agaaaagttg gtttgctgaa agaacgggac
     2341 aagaatctgg aaggtagtga tttcagagaa gggttagctg ctgtactttc tatccgtgta
     2401 cctgaaaatc ttctgcaatt tgaagggcaa acaaaagaaa aacttggtac gccagttgct
     2461 cgtaccgtag tagataacgt catcagtgaa caaatgggct tttatttgca ggaaaatagc
     2521 gaaatgagcc agatgttggt ccgtaaagca atcaaagcca gagaagcgag agaagcagca
     2581 cgtaaagcca gagaagaaag ccgaaatggg aagaagcgta aaaaaggcga atctcttctt
     2641 tcaggaaaat tgacacccgc acaatcccga aaccctaaga aaaatgaatt gtatttagtc
     2701 gaaggggatt ctgctggcgg atctgctaaa caaggaagag acagaaagtt ccaagcaatt
     2761 ctacctttac gaggaaaagt catcaatacc gaaaaagcta aaatgcaaga tatcttgaaa
     2821 aatgaagaaa tcaatacgat gatctatacg attggtgcag gagtcggtcc tgagttttct
     2881 atcgaagact gtaattacga caaagtaatc atcatgaccg atgcggatac agacggcgcc
     2941 catattcaag tattactgct tactttcttt tatcgttata tgaaaccgct gattgaagct
     3001 gggaaagtat atatcgcgtt accgccttta tataaagtat ccaaaggaca aggaaagaag
     3061 caagtcattg aatatgcgtg gacagatgac gaattggcag caatgattaa aaaagtcggc
     3121 aaaggatata tgctgcagcg atataaagga cttggagaga tgaatgcgga acaattgtgg
     3181 gaaacaacga tggatccgac ttcccgtacg ttgatccgcg tccgtatcga tgatgctgcg
     3241 caagctgaac gtcgagtaac cacactgatg ggtgacaaag tagaacctcg aagaaaatgg
     3301 atcgaaaatc acgtgcaatt tacgctcgaa gaagatggca gtatcttaga taaaaaagag
     3361 gatactgaaa tctctccttc agtttctaat gatttattag atgaagaacg agcagataaa
     3421 aatgaaaaca atcagttatt tgaagtagaa taggaggtca cctgatggaa aatcgacaag
     3481 aagtacaaga attaacttta gaagaagtga tgggtgaccg cttcggacgt tattccaaat
     3541 atattatcca agaacgtgca ctgcctgata tccgtgatgg attgaagcca gtgcaacgcc
     3601 ggatattatt tgccatgaac aaagatggca atacgtatga caaaggattc cgtaaatcag
     3661 caaaatctgt cggaaatatc atggggaatt atcatcctca tggtgaccgc agtatttatg
     3721 aagcgatggt ccgcatgagc caagactgga agttgcggga agtactgatc gaaatgcacg
     3781 ggaataacgg gagtatggac ggtgatccac ctgctgcgat gcgttatact gaagccagat
     3841 tatccaagtt aagtggagag atgctagcag atatcgagaa agaaacagtc gatctcgtgt
     3901 ggaattttga tgatacagaa aaagaaccaa cagtccttcc agctcgatac ccaaaccttc
     3961 tcgtcaatgg atcgacaggt atatctgctg gatatgcaac agaaatcccg actcataact
     4021 tagctgaagt gatcgatggc acaatctata tgatcgatca tccacaagcg agccttgaaa
     4081 aattgatgga atatattcct ggacctgact ttccaacagg agggatcttg caaggaaaag
     4141 atgaaatcaa aaaagcttat gaaacaggac gaggaaaagt tattcttcgt tcgaaaacaa
     4201 agatagaggc aatgaagggt aataaacagc aaatcgtgat cacagaaatc ccatatgaag
     4261 taaataaagc gaccttggtg aaaaaaatgg atgagatccg tttgaataag aaaatcgatg
     4321 gaatagctga agtacgagat gaaagtgata gaacaggtct gcaaattgtc gtcgaattga
     4381 aaaaagacgc caatgctcaa ggaattttga attatttgtt caaaaacact gagctacaga
     4441 tcaattacaa tttcaatatg gtcgctatcg accatatgac tccgcatcaa gttggactga
     4501 aagacatttt aagaagttat atcgagcatc gaaagcaagt cataacaaaa cgtagtcaat
     4561 tcgatttagc caaagctcaa aaaagacagc atatcgtaga aggattgatg aaagctttat
     4621 cgattctgga tgaagtaatc gcaacgattc gtgaaagtaa agacaaaaaa gacgccaaaa
     4681 agaatttagt cgacgtcttt caatttacag aagaacaagc agaagcaatt gtcacattgc
     4741 aattataccg tttgacgaac acggatatca cagagcttca aaaggaatcc gaaagcttga
     4801 ttgcgcaaat cacagagttg aataaaatcc tttcaaatga caaagagctt ttctctgtta
     4861 tgaaaaaaga attgcgagaa gtgaaaaaaa attattcttc cgctcgtcta acgacaatcg
     4921 aagacgaaat cgaagaaatc aaaattgata cgcaagtctt agtggcacaa gaagacgtaa
     4981 ttgtcagtgt gacgcgagaa ggctatgtga agcgaacaag ccttcgttct tatagtgctt
     5041 ccaaaccaga agaaatcggg atgcgagaag gcgactactt gctatactca ggtgaattga
     5101 gtacattgga ccatgttctt ctgatcacaa ataaagcaaa tgtgatctac cgccctgtcc
     5161 atgaactacc cgatttgaaa tggaaagatg ctggtgagca catttctcaa acaatctcca
     5221 atctgtctgt agacgaatcg attttagctg ttttcccata tcaaaaaatt caagcagaga
     5281 aaacatttgt attcatcagc aagaatggat tgatcaagca aacacgaatg acagagttcg
     5341 aaccatggcg cacctataag agccgtccgc tcagctgtat gaagctaaag gcggaagaag
     5401 atgaactgat tgctgtgtat ctgaaagaag atcagccagg cttagatgtt ttcttagtaa
     5461 cgcatcaagg aatgggtttg cgctatcctt taacagatgt tcccgttgtt ggagcaaagg
     5521 cagctggagt gaagtctatg aatttgaaag atggagatag gattatcaac gggctgcttg
     5581 tgttagcaga aggtgatacg ccgatcgtaa tcgttactca gcgaggagct gttaaacgca
     5641 tgcttgctca agaaatcagc caaacttcac gtgcgaagcg gggagtgacg gtcatgcgtg
     5701 agctgaaaaa aaatccgcac cgtattatct atatgtcgga aggaagatca aaagaaataa
     5761 ccttgatgaa tcaaaaaggg cagcagttaa cgattgaccc aactgatttc cctataggtg
     5821 atcgaacatc gaatggatca tttgcgatgg atgagaaaaa aggtggagaa gtcatcgaag
     5881 ttatcgatgc tcctgagatt ttcatcgagt cgtaactgtt gtagtatttt aatgaagaga
     5941 cgccatctgt attaatacag gtggcgtctc tttttcattc atttttaata aatccttata
     6001 cgtttgcaaa aaaagatgaa agtgttcaca atgcttaaat gttggtatgt caacgttgat
     6061 ttaaatatat gtaaataaaa cataaaaatt gttaaataaa aaacaagaaa acccttgcaa
     6121 agatagggtg ctgtgttata ctaatcacgt aaaaactgtt acataaaaca gaaatttagg
     6181 aggtccatac aatggagcaa tggaatggat ttaaaggtac caaatggaaa gaaggcgtag
     6241 acactagaga ctttattcaa aataactaca ctgaatatcg cggtgatgac agctttttgg
     6301 aaggcccaac agaagcaaca gaaaaattat gggatgaatt gcaaaagtta aatgatatcc
     6361 aattcgagcg taacggtgtc tatgatatgg acacagaaat cgtatcaact attacttcac
     6421 acgatgcagg ctatttggat aaagatttgg aaaaaatcgt cggtctacag acagacaaac
     6481 ctttgaaaca agcattcatg ccgttcggcg gaatcaatat ggctaacaat gcgctaaaaa
     6541 gcaatggcta tacaccaaac gatgaattga cacatatttt cactgactgg cgcaaaacac
     6601 ataatcaagg tgtatttgac gcttatactg ctgaaatgcg tgctgctcgt aaaaacaaaa
     6661 tcattacagg gcttccagac gcttacggtc gcggacgtat catcggtgac tatcgtcgtg
     6721 tggcattgta tggaatcgac tatttgatgg aacaaaagaa aaaagatcat gatatgactg
     6781 gttatcatac aatgagtgaa gaagtgattc gtttacgtga agaaatcact gaacaatatc
     6841 gtgcattagc gcaaatgaaa gaaatggctg cgaaatatgg ctatgatatt tctaaaccag
     6901 ctgcaaatgc aaaagaagct gtccaatggc tatacttcgg atatttagca gcaatcaaat
     6961 cacaaaatgg tgctgcgatg tcaatcggac gtatctcagc attccttgat atctatatcc
     7021 aacgtgattt ggataatgga gtaatcacag aaaaagaagc acaagaattg atcgaccact
     7081 tagtaatgaa attacgtatg gtcaaattcg cgcgtacacc tgaatataac caattattct
     7141 caggattccc tatctgggct actttatcca ttgcaggtat gggattagat ggtcgttcat
     7201 tagttacaaa gaatgatttc cgtctgcttc atacattaac aaatatggga ccttcaccag
     7261 aaccaaactt gactgttttg tattctgaac accttccaga aggattcaga acatatgcta
     7321 gcagaatcgc tatcgaaagt tcttcgattc aattcgaaaa tgataatcag cttcgtgaac
     7381 aatggggttc tgatgattgt gcgattgctt gctgtgtatc aggaacagtt gtcggaaaag
     7441 acatgcaatt ctttggcgct cgtgctaact tggctaaaac actattatat gccatcaatg
     7501 gcggagtcga tgaagtgact ggcgcccaag ttggaccaga atatcgtcca atcacatcag
     7561 aaatactaga ctttgaagaa gtgaaacata acttcatgaa tatgatggat tggttagcag
     7621 aactatatgt caatacgttg aacatcattc attatatgca tgataaatat tcttatgaag
     7681 cagctcagct ggctttgatg gattctgact tgcaacgcac atttgctaca ggtattgctg
     7741 ggatctctca tgcggcagac agcttgtcag cgatcaaata tgcaaaagta aaagcaatcc
     7801 gtaatgaaaa aggaatagca gttgattttg aagtggatgg cgacttccct aaatacggaa
     7861 atgatgatga ccgtgcagat gaattagttt catggatctt ggaatacttc atgggacaaa
     7921 tcaaacgtca taaaacttac cgcaactcaa aaccaacaac ttcattattg acgattactt
     7981 caaatgttgt ttacggtaaa aatacaggaa atactcctga tggccgtgaa gctggaaaac
     8041 cacttgcgcc aggagcaaat ccaagttaca atgcggaaca aagtgggtta ttagctagcc
     8101 tgaactcaac agctaaaatg aattacggct gtgcattgga tggaatttca aatacccaaa
     8161 caatcaatcc ttcaggtctt ggaaaagaac aagatacaag aatcgaaaac ttgcgtaatg
     8221 tcttagatgg atacttctca aaaggagctt atcatttgaa tgtcaatgta ttcagtaatg
     8281 atttattgcg tgatgcaatg gaaaatccaa tgaaatatcc gaacttgacg atccgggtat
     8341 ctggttatgc agttaaattc cgtgacttga caagagaaca acaattagat gtcttgatga
     8401 gaacttcaca cgacagaatg taaaaagttc gtgaaaaaag tttttcgact tagcgtcgaa
     8461 aggacgttga atagccatcg catcaaaatc gaataatcag tatgcttatt tgaaagaaac
     8521 gatttacagg ggcaggactt gtatgttccg tccctgtaaa ttttacacat aacgaagcgg
     8581 caattgcgaa aaattttgtt cagaaagctt cgcttcgaca gctaacttgt acttaaaatg
     8641 aaatcaaaga aaagatgtga acttaaatgg aagaaaaaac aatcggctat gttcattcta
     8701 tcgaaacttt cggttcagta gacggacctg gactgcgctt tgtcgtgttt atgcaaggat
     8761 gccgcatgcg ttgccaattt tgtcacaatc cagatacttg gaatattggc ggagggaaag
     8821 aatacacagc agatgaactt ttagataaag cagaacgctt cagaccttac tggggagata
     8881 aaggtggtat tactgttagt ggtggagaac ctctattgca gatcgatttt ttgatcgaac
     8941 tatttaaaaa agcaaaagag cggaagatgc atactacatt ggatacatgc ggaaaacctt
     9001 ttacgtatga agaacctttc ttttcacgtt ttcaagaatt gatgaagtat acagatttac
     9061 tgttatttga catcaaacac atcgataatg aagagcataa aaaactaacg cattgggaca
     9121 atgaaaatat tttagaaatg gctcaatatt tgtcaaaaat caacaaaccg gtttggattc
     9181 gccatgtact agttcctgag cgaagtgatt atgatgaata tttgatccga ctagacaact
     9241 ttattcaaac cttgtcaaat gtagacagag tagagattct tccttatcat acgatgggaa
     9301 aatacaagtg ggaaacactt ggtttgaaat atccattaga agggatcgaa ccacctacaa
     9361 aagaacgtgt cgaaaatgct aaacgattgc ttcatacaga agagtataca aaatatttaa
     9421 cgcgataggt cgcatcggaa agaagataag tattgcttct ttccgttttt ttgctattat
     9481 taaataggag aaatcacaaa ggagcgaatg acatgtcaaa aattttagtt tttggtcacc
     9541 aaaatccaga tacagatgca atcggggcag ccattgcgtt ttcacacttg caaaatgaat
     9601 taggtaaaga aacagaagca gttgctctag gtacacctaa tgaagaaaca caatacgcat
     9661 tagaccactt tcagctatct gcaccacgag tagtagagtc agctaaagca gaaaatgcag
     9721 atgtcatgct tgtggatcat aatgaattcc aacaaagtat ttcagatatc agcgaagtaa
     9781 atattttagc tgtagtagac caccatcgta ttgcaaactt tgaaacagct aatccattgt
     9841 actatcgtgc agaaccagtt ggatgtacaa gtacgattat tttaaaacta tataaagaaa
     9901 accaagtaac aattcctaaa gaaatcgcag gaatcatgct ctcagctatc atttcagata
     9961 cattgttgtt caaatcacca acatgtacgc ctgaagatga agcagctgca aaagaacttg
    10021 cagcaatcgc tgaagtcgat ctaaacactt atggacttga aatgttgaaa gcaggaacaa
    10081 atctaagtga taaatcagct gcggttcttc ttgatttgga tgcaaaaagt ttcccaatgg
    10141 gcagttccaa cgttcgtatc gctcaagtca atacagtgga ccttaatgaa gtgatggatc
    10201 gacaagcaga gctagaagca gcaatggaag atgaaatgaa agcaaatggc tacgatctgt
    10261 tcgtattagt tgtcacaaac atcttagaca gtgattcaga attacttgtt gctggtaaag
    10321 gaaaagaaaa agtagaagaa gctttccaaa caactttgac caacaaccgt gctttgctta
    10381 aaggtgtcgt ttcacgtaaa aaacaagtcg tacctcaatt gacggctgta tttagctaat
    10441 caaatggtag tatgaagcat tcaaaatgaa tggataagcg attgatataa aaagaaacat
    10501 agaacatact aaaggccgaa gaaatggagg agaataacag tcaattatga ctcttgttct
    10561 tcctcctttt tacgtaaaag ccttttaagt aaaataaaac ggatagaaaa gagaacatat
    10621 atgaactatt attcaaaaaa taaggaaaac ttttatcaaa aactgaccga tgatccgctt
    10681 ttttcttcat tgaccgatta tctatatgaa catcgagaac aagaaacgat tctaagagaa
    10741 ttgaaaaaag aattttcgca aaataaattt tcccattttc ttgatttatt gatcgatgca
    10801 ggattaatca agagggaaga acgaagatat catttgaact ttccaatatt tgatcctaaa
    10861 gattacttgc aacaagccac ttcggctgct gaaaccatag ctgaacaatt gaagagactc
    10921 tctgttgatg aacaaaaatt agcgatggga gaagttattt gggcgtattg tttcgaagat
    10981 gaacggaaag aagcgtattt ttatggagta agaaacagcc gagagacaga attgctgagg
    11041 acaactgcag gaaatgagaa gtaccgtttt atcacacttt cctctataga acacttcccg
    11101 cttactttgg ctaattactt ttttgtacag aagaatcagc ttcctgtaac gaaggcattc
    11161 aaagaattag ccgaacttat tggagacgta aatgaatcgt acttttttga tcaaatagaa
    11221 gttatcgttg acaggatacg taagaataaa tataaaaatc gccggcctag tattttccat
    11281 cagtctctac ttgtgacgaa tactataaag gaagaagaat cattcacatt agaattacct
    11341 attgtcgaaa aaaacaattt tgagattgaa ttaccaacat tggatccttc attgacaatg
    11401 gaggaaatgg cctttcttaa acgacaaatc ttttctgagc tgagcaagaa atttataccg
    11461 catgcatttt cttatatcaa agaatatgga acagttttag tgagtaaaac ctaagagagc
    11521 agtaagcaaa aattatactg actcttgcag gaggagcctt tctcttcctt tatggttaaa
    11581 agaattattt gagtattttg cctatctacc acctattaga ttcactacat ggtctggaaa
    11641 caaaggaatg caaaaaaatg gtgagaaatg tggaatgaca aaggaagtag tgataagaaa
    11701 agttagattt ttaaataatc aatattatga ttcagtcaag tatggcattt tatgggaaga
    11761 actagctgat tagattagga agtccatttg ataatccaga atcactaaga aacgaatggc
    11821 gagtcattaa taatttatcc aatcttgggt tattctttta gattgaagtg tttaaaacta
    11881 aaaaagcatt tatgaagtcg taatagtcag gcttcaaaat gctttttatt ttgtttgttt
    11941 tttctttgcc acataaatac acctagactg acgatgaaga gcatatccaa cagatttcct
    12001 gcgacttgga tcgtcgaagg gttggtcagt ggcattaaag caaggacaaa aaaggaaaac
    12061 aagctgtaaa taaaacaggt gacaggaact aatcgaaaga agagcggaca tttcaattgg
    12121 ctaaaaatga gtgaaaaaat aaaataagta aaaatggata aaatcacgac taaaccattc
    12181 atgataaaga agaaaagcgt attgtgatta aacgaataaa aaagaattgc taaaaaagaa
    12241 aacgttttaa atgcaatcaa tacgcttgaa gcttcgttta acgtaccagg atgtcgatga
    12301 aaaaaatagg caccgaaata aacagaaaac agtaagccgc aaagagaaga caaaatcaaa
    12361 aaaaacggat tttcttcggc ttctgtgata tcagaatgat ccaaaagcaa ccagcctaat
    12421 gcactagaag gcgcatgtga ggtcttaagg tatgaataac atagaaaaaa taagatcgtc
    12481 aaagttgcaa aaaaagagcc taaatgtaaa aaattagtgg ttctacgttg aatttccata
    12541 atatctccaa attaaattga taagtatata aagtataata acaaattgat gagtatatgt
    12601 cgatgttttt taatcaaaat aataaataaa aactgtctaa catttaaaat ttaatttaga
    12661 tattagacag tttttaagtt tgtgagttat tttccttgtc gttttctcac ttttttagtc
    12721 cagaaaccac ctgaaatata ttttggctca taagaaatga taaaagcacg ctcttcgatt
    12781 tctttgatca ggcgatacag ttcacgttcg ctttttctag gagaaagtat ttcgagaact
    12841 agccgctcac cttccagccc cattgcagaa gtctgtgtca caccataacc gtgttctctc
    12901 agtatacccg gcaaactttt atcttctgcg ctatttgctg gcaaaatcgt tgtgaccatg
    12961 atgtatccta atgccaattt gtcttcaatc aaaattccga cactgatacc tactgcgtaa
    13021 cctaacgcat agacaaataa attcagtgga ttatctaaac gatctaaaac aagggataag
    13081 ccgacgatat aaatcgtgat ctcgaccata ctgacaagtg gagcaatcag tcgatagcct
    13141 ttcattgtca acatgaaacg taacgtgttc agagtgatat aagcaaaatt aatgaggaag
    13201 atcatcccca acatttttgg atcaatcatt tgtaaaactc ctttcattta tataacaaca
    13261 atatcaaaaa aaatcgtaag tgaagaaaaa ttgaaacttt atacatacaa aaaaatgata
    13321 aaatgattat aatagaatta taaagatagg ttaggtgatt aaaatgaaaa cggtcaatcg
    13381 tgtgttttgt gccagccacg tgctaagtct ccttctcagt atatacttag gtgtctattc
    13441 gattcaacag ccaattgagg tagagaacat tgtttttcag atgtcgctga cagatggttt
    13501 aattttaagc gtttttttct ttttgatact gtttattggt aatattttcg gtagcgttgc
    13561 cagttttttg aatttttcta tttatccact cctttcgcta gcattaggag tggtgggact
    13621 ttgttctctg tgcttatttc ccgagccatt cagtcctgca tttatattat ttggtacact
    13681 gaacctgttc cagacaactg ttggagcatg gttgctatgg cgatcaggaa atttaatgaa
    13741 aataggtgag taacaattga atccaattat attgaaacgt tctgtccatc atattccagt
    13801 gttagaagtt gttctgaaag aattaagaga ggaacgtatt cccgttgtca tctattatca
    13861 cggatggcag acaagtaagg agttagtttt gacgcaagga agaaaaattg cgcagcaggg
    13921 cattcgtgtg atcctgccag atgcgatgaa tcatggggag cgcaaacagc cggtttcttc
    13981 tattccatcc tatacatttt gggatagtat ctacggaaat ctgtttgaat ttgacacact
    14041 tatcaagcat ttagaaaaaa gaggtcttct acatgatcag cttgcagttg gcggggtttc
    14101 gatgggggga atgacaacat gcgccttgtt ggctaaacat cctcatatag tagcgggcgt
    14161 gtgtttgatg ggttcccctg cacctttgga atatggaaaa gaaatcgtaa ggcgcgcatc
    14221 ggaatataat tatgtcgtac caaaagacta ttttgatttg atttcatggg ttaagagcta
    14281 tgatttgtca ttgcagccgg aaaagttagc tggacgtcct ctgttctttt ggcatggaca
    14341 agctggcgaa aaaatccctt atatacaaac ggaacgattt gtagaaaaaa atcggcataa
    14401 gtcttacgga aaagaaattg tttttcgttc ctcaaaaaca cagcgacata tggtacaaat
    14461 accactaatg gaagaagctt ccactttttt agcaaaaaat ttgataaaaa agtataaata
    14521 attgaaacgg aaaatcactc atgacgatag aggattttcc gttttttatt ttgggctata
    14581 ataaactctg ttaggaaaat ttggtataat tgatagtaag aatgacaaca tgttagaaag
    14641 gaagagagca tgcccacttt agcagatgtt gcaaaacgtg ccaatgtttc aaaaatgacg
    14701 gtctctcgag tcatcaatca tccggaacag gtgactgacg aattgaaaga gttagttttc
    14761 tcagcaatgg ctgaactgga ttaccgtcca aatattgctg caaaagcact tgtcacgaat
    14821 cggtcgcaga tcatcaaatt atttatactg gaagaaatcg acacaactga gccctattac
    14881 atgaatttgc tgatgggaat cgctaaacgg atcggtaaag cgcattattc tctccaatta
    14941 gttacaaatg atgccttcga cgtcggttct tgtgatggat acatcatcac aggtgtcaga
    15001 aaaaaagact tcgattggat cgaccgtttg gaaaaaccag ttgtcttgtt tggggaaaat
    15061 tctgaaggat atgattatgt agacagcgat aatgaatatg gtacagcaaa agcaacgcaa
    15121 tatgccttag aaagagatta tcaaacgatt atttatatcg gtatcgaagt ggacgagcct
    15181 tttgaaattt caagggaaac tggttattta tctgtgatga aggaagttga tcttcctagt
    15241 aaaatcttgc ggtttccaaa tcattcgaca gaagtagaaa gatatatgac agaaaactgg
    15301 gcagatttta cagataaaac ttgttttgta tgtagttcag atcggctagc actaggagca
    15361 gtaagaggga ttataaatgc tggaggacac ttgcccgaag aatttggtgt gattggattt
    15421 gatggggtat ttttagacca aatcagttca cctaaattga caacgatcaa gcaagatatt
    15481 atacgtatgg gtgaagtatg tggagaaatg ttgttaaaaa aaatagaaga aaaaggggcg
    15541 agtcaaggtt atcgtcgttt ttttcctgaa ctagttatca gagagacaac gaattaagtc
    15601 ttattactat atatatattt atgaaattca tcgctatttt cttaaaataa tcagcgcatt
    15661 gctactgaaa acaatgaatc tgtgctatta ttgagaaaag ttccattttt gagaaggatg
    15721 gtttgaatga aagaaatcag acgaaaacat ttccgttttc ctgcgtacga tgatgagtta
    15781 ggcgtaaaat taaccaacga caagaagcga gtattatttg acggacaaga agatcttttg
    15841 actgaacaga atcagtcccc gtttgaacag atgaaagaat ttcatttcac gaacacgaac
    15901 accgagaaaa tccgtcgcaa gcgtcgtgca acaaatggat tgaagtcagc tccgcgtaag
    15961 gaaaatttgg aaaagcataa aggaaaatta ccggattata ccggccatta ccaatcagaa
    16021 atcacatcga caggacgaaa aaaacttttt ggtgattcct ctcgttctgt cagacaaagt
    16081 gaaacaagga cagagtccaa gcatactaca cgaaacgcat ctgttgacac gaaggtgcgg
    16141 gagcgttctt attttgttcc taaatatgta cccgcatcga ttatcccaga ccctagagaa
    16201 agcaaaattt ctgaggatca tttaatcgaa tcgatgaaaa aaacggatga ctcttatctg
    16261 ttgttcgata cagaaccgac gccgtatcaa gaaaaaagaa atggtgagcc gtctgtacga
    16321 acattcaatc gaacaaaaac gttagaggaa acaaagcagt cagaagaaaa aaaatcgaaa
    16381 aaaagccatg gtatcttaga acgctcatta caaggattga tcgatgatca aggaaactct
    16441 ttgggagaaa atagctattt taaataagtg atatacaaat ttatattcgg ctacagttgg
    16501 aaaggaaacg ctgcggcgtt tccttatttt atactctatc cgaaagttta tatcgtatcc
    16561 tcaaattttt ttgagtttaa gcgaattttt tctcccaata agtaagaaaa taatggcaaa
    16621 ataaaaaaac aaactatttt cgcagatcgt ttgcaaaaat agtttatttt tttataaaga
    16681 agattttact gaataatatc attttagttt acataatgat atttctgtaa attaaataaa
    16741 gtagtgaaaa ataagaatca gtgctctaac tgttcaagag gatcaagtgg ttcaaatgtt
    16801 tctgtagtct gttttgcttc caattggggc aaaacagatc caatttccag atacttcact
    16861 ttattcaatg tataagatag aatagaacag ctaagtaatg tatacagaaa atgtgtgaga
    16921 tccaaataaa gcaaggagac aactaaaata ccaaaagtaa tcaagaaaag acttttgcca
    16981 atcttaatat gaaaatattt ttcaatggct tgataaatga tatctgttcc gcctgtgctt
    17041 ccgccgaatc gaaagacgag accgcaacca atgccagaaa gaatacctgt catcaaacta
    17101 ttgatcagta gactatctac agcaaaatgt atatgaaggc tctcccataa atgtaaaaag
    17161 aaaactagcg caaatgttcc gacgatcgtc cggagaaaag cgtgttttcc aaaaagaaac
    17221 aatgagataa gcaataaagg taaattaaaa agcagtgaag tgacagaagg agcgaatcca
    17281 aaaagattat gcaaaagcaa agcaatacca gtaaccccac catctgccag cttagatgga
    17341 atattgattc ctgtcacagc taatccgtag attcctgcgc ctaaaatgat tccgcacaat
    17401 tctgtaaata aatttaattt tttcatttct agcctctttt cttttgaaaa ttttcagcaa
    17461 cttctttatt atactgactt atactcttac ttcaagagga aaatgaaaaa aaattatttt
    17521 tggctgtttc tttttattta tcaaataagg agtggaaaaa tgcgagcagc agacttattg
    17581 acaattctta caaaatcacc caaaaaaaca gagtatcaag gagttttttt ggctcaagaa
    17641 caaaaactgg tgcctgtgac aatggtccag ataaataaag caaatcaatt tatcttttta
    17701 tttgaacacg gcaaagcacc acttgctatg aaagacatct ttcttttttt gatgaagaac
    17761 cgtgagaaag ctgtttatta tcagtcaaaa gaagaactca ttcctcttta tggagtgaaa
    17821 gagatagaaa ataaagtggt gatataagta aaaataagaa aacaagacgt ttatgatgtc
    17881 aaaacaacca ttttttacat ttttggcaaa aaagtgtcat gatacagtat aatattcgtt
    17941 gaacaggcca ataaaggtgt tctcccccac gagatttcta ctttattggc tgtttctttt
    18001 tattaaaata aaagttgtgt gtgtaaaaaa gatatagctg attccaagtg acaatttcgt
    18061 atagattttt atggtattcg tagtgaaaaa acgagaacca aaaagttgat ccgactttgt
    18121 tgcttggatt ctttttttgt cagcatattt agaggtattt ttttcttttt tttgttcgtg
    18181 ctgtaaggtt aaggcaagac aagttagttg ggaaaaagga aagaaatgtt tatacttaaa
    18241 gaataacaga aaggaaggtc gcatgaataa ttttatacaa acattaagtg aaagaaaagg
    18301 cgagttgctg gaagctgcat ttcaacatct gtccatttct ctcatttctt tgctgattgc
    18361 agcactgatt gctattcctt tagcgatttg ggcagccaat cataaaaaaa tggcagaagt
    18421 cttattgcag atcacgggtg tgctccaaac gattccttca cttgccttat taggtttact
    18481 tatcccattt gtagggatcg gaactgttcc agcattgatt gcacttgtta tttacgcttt
    18541 gcttccgatt ttccaaaaca cgtatattgg tctagctgaa attgacccgt ctattgaaga
    18601 agcagcggta gcatttggta tgtccagaat gagacgcttg ctgaaagtag agcttcccat
    18661 cgcattacct gtcattatct caggtatccg aactgcctta gttttaatca tcggtacggc
    18721 tactttggca gcattgatcg gagcaggtgg attagggaca tttattttgt taggtattga
    18781 ccgaaataca cctgttttga cattgattgg tgcgatcagt tctgccttgc ttgcaattat
    18841 attcagcgga ctgattcgct ggttgcagca taagaaacct cgatattcca tcattacttt
    18901 agcagcagtg gtgtgtttat ttggcggcgt ttctttatat cagtctgcct tgtttaaaaa
    18961 tgaaaccatc acgattgctg gaaaattagg agcggaacct gaaatcctga tccaaatgta
    19021 taaagaattg attgaagaca acacaaaaac agaagttgaa ttaaaaccga attttggcaa
    19081 gacgagtttt ttgttcaatg cactggatca aggtcaaatc gatatctatc ctgagttcac
    19141 aggtactgtc ctagaaagct tggtgaaggt acctgaagca atgaaaagtg ctgatttgac
    19201 aaaagaaaaa acatatgacg aagcagaaga attattgaat aagcaattcg atatgacatt
    19261 attaaaacca atggcttacc aaaatacgta tgccttggca gtcaagagat cttttgcgaa
    19321 cgaacatcaa cttaaaaaga tttccgattt ggcagctatc tctgatcaga tcaaagcggg
    19381 attcacactg gaatttattg atcgttcaga tggatataaa ggaatccaag aagcatatgg
    19441 cttgaatttt tcaagtgtac aaagcatgga gccaagtttg cgttaccaag caatcaataa
    19501 tggagatgtc aatattgtgg atgcctattc cacagatagc cagctcaagg agtacgatct
    19561 agtgactcta gaagatgatc gagggttatt cccagcttat caaggcgcac cgctgatgaa
    19621 aaaagatttt gctaaagaac atcctgaaat cgttaaagca ctgaataaat taagcggaaa
    19681 aataacagag gatcaaatga ttgatatgaa ttaccaagtc aatgtcgaaa agaaaaagcc
    19741 gacagaagta gcacgaatct tcctgaaaaa tgaaggatta gtaaaggagg aagatcagtg
    19801 actaaattaa tcgagttcaa acatgtgcaa aaaaagtatg atggaaagta tgtcatcgat
    19861 gacctaaatc tggcaatcaa aaaaggagaa atctttgttt tggttggtcc ttccggtagt
    19921 ggaaaaacaa ctactttgaa aatgatcaat ggattatcta aaccatcagc aggagacatc
    19981 tacttcaaag gaaaatcgtt aaatgaatat aatctgcaga aaatgcggtg gaatatggga
    20041 tatgtgctgc agcaaatcgc tttgttcccg accatgacag tcaagcaaaa tattgaagtc
    20101 atccctgaaa tgttaggttg ggaaaagcag aaaagagcag accgtgtaga tgaacttctt
    20161 caaaaagttg gcttatctcc tgatatttat cgagatcgta tgcctagaga gttgtctgga
    20221 ggagaacagc aacggatcgg gatcatccga gctattgctg caagcccaga tgtgattttg
    20281 atggacgagc catttagcgc attagatccg atttcaagaa actcattaca agaattggtt
    20341 ttgtccttac acgaagaatt gggcacgacc atcgttttcg ttacgcacaa tatggaagaa
    20401 gcaatcaagc taggtgatcg tattgcattt atgaaggatg gagaaattat ccaatgtgac
    20461 acaccagagc agttattgat gaatcctaaa aacgactacg ttcggcattt ctttgatgaa
    20521 ccgaaacaga cgaaagagtg gcgagtagaa gatttagtcg tcaatggata tttcttaaat
    20581 gaaataccag aaaatgctcg tcaacaagtt tgctttgata cgcctatgaa agaagtatat
    20641 tcgcttcttt cggtgtatcc aagcattgtg atagtagaaa agcaaagaag tattgggtcg
    20701 ctgacaagta aagaaatctt tgctttttta agtcgagagg aggaaggaaa tgaaaacata
    20761 tgatgcaatc atcatcggtt caggtgtgag cggcttaagt gctgcttatg gattgaaaga
    20821 agcaggtaaa acagtactag tggtcgaaga agatctatgg ggcgggactt gtcctaaccg
    20881 tggatgtgat cctaaaaaag tcttgttaag tgcagtagag gcacgtaatc gggtaaaaca
    20941 attgagtgga aaaggtttta acgagatccc aactgccaac tgggaagaac ttcaaaaatt
    21001 caaacgaaca tttacggatc cagtcccaga aagccgaaaa aaacaattag cagaagctga
    21061 aatcgatcat ctttcaggaa ccgctcgttt tttggatgat tcatctattg aagtcaacga
    21121 agaagtcttc catgcggatt acttagtttt ggcaaccggg caaagaccta cgatcttacc
    21181 agtggaggga aaggaatact tgaaaactag tgcagacttt ttatcattgc ctgtactgcc
    21241 taaagaaatc atttttatcg gtggtggtta tattgctttt gagctagcta cgattgccaa
    21301 tgctgcaggg agcaaagtaa ccattgtcca tcataatcaa cggccattaa aagaatttga
    21361 ggcgtctttg gtagaggaag ccgtccatca aatggaagca tctggcattc agtttgcttt
    21421 tggtgttgaa acccaaaaga tcatttcaga aggtactcgc tatcgtttag tcggaaaaga
    21481 gacggaatta gtagcagata tgattttttg tgcgactggg agacagccga atacagaatc
    21541 tttagcactt gagcaagcga atatcgtctt tgataaacac ggaattgcag tcaatgatta
    21601 tctgcaaacg agcaatccaa aaatttttgc gtgtggagat attgtttcaa ggaaaacccc
    21661 aaaattgaca ccagtcgcca cttttgaagg aaattatgta gctaagcgga taacggatgc
    21721 aacaagcgaa cctatcaaat atccgattat acctacgatc gtctacgcca gtcctaaact
    21781 tgctgaagta ggagttacaa aaagtcacgc ctcttcgtca gatcaagtgg tagagatgga
    21841 tcttaccagt tggttcacct atcatcgtgt caatgaacca gttgctaagg ctgaattgac
    21901 ctttgaccag caaaattatt tgattggtgc tgcagtgatt agcgagcaag cagacgaatt
    21961 gatcgatgat ttgacactcg tcatcaatca aaaattgact aaaaaagagt tggatagcta
    22021 tatcatgggg tatccgacat tggcaagtga tctctcctat ttattgaaat aatcagcatg
    22081 ataactaaag cgcttgttgc tttttccttc ttgtgctaca ctttaaaaaa tgaatacctg
    22141 tttctgggga tgtcgtagac gacatgagag taagttgtga acttagaccc attgaacctg
    22201 tcagttaata ctggtgaagg gagaaacata gcagacgctt gaagcgggtt actatgtcgt
    22261 gcccatttca agcgtttttt gttattcata ttagaagaaa ggaggtaaca aaatgaagaa
    22321 aaatctttat ccagcagtca gtatggcatt cattttaatt atttggcaga ttgttgtcat
    22381 agtttggaaa atacctgcct ttattttacc cggacctgct gctgtatttt ctgcattagc
    22441 ggcagatgca caagtattac tttcccattc tgtcacgaca ttaaatgaag cagtgcttgg
    22501 tttggtaata gctagcgttc tttcttttat tactgccttg gcaatggatt attggaagtt
    22561 tttagaaatg tctttttatc cgttactagt gatttcacaa atgttgccaa tcatggtgtt
    22621 agggccatta cttaccctat ggtttggttt cggtatgctt ccaaaagtga tccttgttgt
    22681 cttgataagc tattttccga tcgtagtttc tttttcggat acattgagga aagtatcaaa
    22741 agagcaaatc atctttttga aaacgatggg ggcagataca gggaagattt atcgaatata
    22801 taaaatacca gcgggtttat ccggcttctt ttccggttta aaagtggctg ctacttattg
    22861 tgtcagcgga gcagtcgttg gagaatggct aagcgctcaa gcaggcttag ggtattacat
    22921 gatacgcgta aaaaacagct accagatcga taaagttttt gctgcgatca tttgtgtcat
    22981 tctattgagt ttattgctga atggcgcttg ttcattattg aaaaaagggt attatcgtat
    23041 gctttatatt ttttaagaga aggggatcaa atgaaaaaat tatggctttt attaccgcta
    23101 ctgttgcttt tatccgcttg tggcactgca aaagaaacaa gtagcaaaca agaaataaag
    23161 gatttgaaaa aagtgacact tgttttggat tatgtaccga atactaatca tactggcatc
    23221 tacctagcaa aagaaaaagg ctattataaa gaggctggtt taaatgtcca aatcatcgaa
    23281 ccaggagata attcgacaag tattggtcta gtaggtgcgg acaaagcaca atttggtgta
    23341 agttatcaag aagatgtcac ttatgctcac gcagatggac agaatatacc agtcaaagca
    23401 attgctacag tgatcaaaca taatacttct ggattcgcca ccctatcaga cagtaacatc
    23461 cattcaccaa aagattttga aggaaaaaca tatgcaggtt ggcaaagtcc aagtgaagaa
    23521 gctgtcttaa aagctgtgat ggaaaaagac ggcggggact tttcaaaact gacaatggta
    23581 ggaagcaatg gagaagggcc agaaagctta ggaaaatcct cagatatcca atggtacttt
    23641 gaaggttggg atatgatcaa agcaaaagaa gcgggtattg aactaaacta tatcccattg
    23701 aaagaattag atgaacggtt agattactat actccggtaa ttattacgaa tgatcaactg
    23761 atcaaaagtg atccagaatt ggtacagtct tttatggatg ccacgaaaaa aggctatcag
    23821 gaagctatta aggatccaaa tgacagtgct aaactgttgc aaaaatatgc aaaagaaaat
    23881 gatcggacgt ttttagaaga atcacaagca ttcttgtcaa aaaattatac ggatgatcct
    23941 gagaattggg gattgatgga agaaaaagtt tggcgcaatt atacagcttt tatgcaggaa
    24001 aacggattga tcaagcaaga tgtaccttcg caagaactat tcactaatca gtttataaaa
    24061 taggagtgat agatatgtca atccaaatca gccacttgaa tgtagtcatt gaaaacctga
    24121 aaatattaga agacatccat ttcactatcc ctaaagatac ctttacatcg attgtcgcgc
    24181 caagcggagc cggtaagtca acattgctga aaactttaac aggagtccag cctatgactt
    24241 ctggaacgat caaagtagac gatcaaaaag taactggtct ccatacagca tttagttata
    24301 tgccgcaaga agatatgtta cttccttggc tgagcgtcta tcaaaacgtt acgttatatc
    24361 aaaaaatcaa tcatctaaca atcaatgaag aacaagtaag ggattatctg gatatctttg
    24421 ggttaaacgg ctatgaacat tttttgccgg aacaattatc tggcgggatg aagcagcgaa
    24481 cggccttgtt acgaacaatc atgaatcctt cttcttactt gcttcttgat gaaccatttg
    24541 gagcgttaga tgctatgacc agagggcaga tgcaagactg gatgttgaag ctgcctaaaa
    24601 aagcaaagcg gactacttta cttgtgacgc atgatatcga agaagcaatt tatttatcag
    24661 acaggattct tgtgctttcc gcccgtccgg cacatgtgat tgctgagatt caagtgcctg
    24721 aaaaacgacg gtcacgtgaa tggctactgc agcaatcaga gttgaagcaa acgatttatc
    24781 agttattggc aggtgaatta gatgttaagt gatgctcatt gtcatttaga tgggagtcag
    24841 agtttagcac tccttcagca ggaacacacg attttgacga tcatcaattg tgattcgcca
    24901 gaagaatgga aggaaaacag acagcttgca gcaagtaaga ctcaagcctt aagttacggt
    24961 atccatcctt ggaaagcaga tagctatacg tttgaacaag ttgagccttt tttgaaaaaa
    25021 gcaaggatca tcggtgaaat agggttagat aatatttgga cgaatgtacc gatgactaca
    25081 caaaaaaaag tatttgagcg acagcttgct tttgcagcca taaatgagaa acctgttgta
    25141 ctgcacacaa aaggatgcga aaaagagatc ttaaattata tccaagctta ccctaatcac
    25201 tatttgatcc attggtattc ttctttggac tatcaacaag actatattga tttaggctgt
    25261 tatttcagca ttggtcttga tttgaaaaag aatccagcag tctggcaact agctaaagca
    25321 gtcccaatcg accacttact tattgaaacg gatggactac atgcagcaga gtgggcttta
    25381 ggggggattt tttcagaaaa agattatgtc tcactgcttg aagaacagtt aaagacaatc
    25441 gctgagatca aagagctatc agttgaagaa gttaaaaaaa atacttatca aaacttggaa
    25501 cgtttcatta gattaggtaa ataaaaaaga gatgtgacac aactagtgtc gcacctcttt
    25561 ttggctttct ttgtataaaa gtaaactgtt tgattaataa atgaatctta gtaccaaccg
    25621 tttgcttccc agaatgcttt cgccgcttcc caagaaccat aacgtgaagt aacatattgt
    25681 tctgctactc tttcttggtt tgcagcagag tagtcaccat ttaagtaaga agaatctaat
    25741 tggtaacgtc cgatgtaacg tccgttcgtt gctgtgtaag aaccgcttga ttctttttgt
    25801 gcgatccatt cttttgcaga gcttgtgctt gctggagtag cagcagtttc tgttacagca
    25861 ggagcaggtt gtgtttcagc aacaggcgct gcttgttttt ccgtttgaac cgtttcttgt
    25921 acaacaggtt gttcagcttg gactggtgct tcttgaacgg ctgcttgagg ttcagcagct
    25981 gcttgtgcag agccttctgt tgggattgtt aattgttgtc ctgagta
//
LOCUS       DAFBVQ010000037        25935 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.037, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000037 DAFBVQ010000000
VERSION     DAFBVQ010000037.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25935)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25935)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25935
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.037"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(1236..1901)
                     /locus_tag="LLC22_001712"
     CDS             complement(1236..1901)
                     /locus_tag="LLC22_001712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5434994.1"
                     /translation="MNTGEKIRTYRRNCKLTQKELGEKIGVSDKTISSWENSRTMPDL
                     EMLSLLHHTLGLPIDFPSIESATESIEPTLPDEPLVNKKSYSSKQPFSLKKTLSFFLL
                     VFCLVYLFLINYQYKNETIDRFNPFLKPQIGYTTLPVGYVDNSIERWVCNDIFGHGTW
                     LSFHAGEVEKEKNHAVIKHKGKHVMNVRLLTWEAIPSDYQEILSQDYDDALKRSPQEP
                     DRH"
     gene            2081..4063
                     /locus_tag="LLC22_001713"
     CDS             2081..4063
                     /locus_tag="LLC22_001713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1430 domain-containing protein"
                     /protein_id="HBK5434995.1"
                     /translation="MSGFALVSINKQVLYRTNEFFHQTDTYTPIRLPQHFIGQEEYEQ
                     LIMVFENVSSETELSYMKKTVNESNEVDTSWNFKIQPKLEMTLYYQGDVKSSHEKVPY
                     SNTSFRVTSIEESIKIKDFEGEFFLMTREKEAYERFISLFTDRFNQAFHTDYATNIFE
                     DFENSYSYSVISNTDVYNYRVYLTIGLILLFLLLSSFFLLMNKEISLLLNNDFSLHQV
                     LWCLLGKKKIIITFIIAGIIGGFIFMYYKEQFLYLFQMYVFLFSGIYGISLISLLLVE
                     KIASLREAFNYIQYILFTFGLLFSLLLTVANVELATIVFSSSQLAVSHEPPKEIAGED
                     YHVFYPVTIGKNHVDFIYSNRFASAADQELYETLNKNGSILVNVSDYLNEENEQFGRG
                     IKINLNYLKKFPLIDVSGRLIQITEKETHPVILIPERYRHTDLKNDLAQITEYYQEIS
                     EKEPKFLFIKNNQPIYTFIPSIPWIEHYPVVEILTLKNSMYLERNILSGEIYPPLKIK
                     IGSLSKERLFELIEESQLRDNLQLSFPYTQTEEIAVKVLSRSFHYLIQIFLLTFFSFF
                     LLSYVMLCIYFVYNCRKIAIFRSSGYSLFETYKDFFMMNLIKWGTTSVIFLFLIEREP
                     KYLFNIFFFSFIDFILSVVFILSTEKKSQLLLMNGG"
     gene            4067..4705
                     /locus_tag="LLC22_001714"
     CDS             4067..4705
                     /locus_tag="LLC22_001714"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5434996.1"
                     /translation="MEPLIVIKGAKKIIRNKTILHLDRFTADAGDLVTVVGESGAGKS
                     TLLNILGLNDQFSSGQFYLFDQETKQLTGREKRLIKRNTISFLFQDFGLIEYETIDFN
                     LDIGLKFSNLNVSDKRTAKYEALKKVNINKKLSTPIYTLSGGEKQRIACARVLLKNSK
                     IILADEPTGSLDKRNKDKVVEILSQQASQGTLVIVVTHDPYLTKIGNKKIML"
     gene            4733..5161
                     /locus_tag="LLC22_001715"
     CDS             4733..5161
                     /locus_tag="LLC22_001715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288545.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434997.1"
                     /translation="MKKAVIICALGIGFVGGNAMSSEVEANSVHGEIYYKSLKPGEIH
                     FDAKGNIIKSNLPVDREISRTAINHSSGRWVYYSDTTCTRKTGHSNHYSRVYNRHGAK
                     EKVGNSIRSANATKGVWAYASATGNRTDTFSCWYNPTGWY"
     gene            5618..6529
                     /locus_tag="LLC22_001716"
     CDS             5618..6529
                     /locus_tag="LLC22_001716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBK5434998.1"
                     /translation="MKKRFLALAIVLGTGLLSGCTNAGEKTAVSYKGGTISEQEVMDS
                     LKKMQGADSAVQQLIVYQVFEDKYGDDVSTKEIDSQYDQTKKQLGDSFDSQLKSAGYT
                     EQTFKDSIKQSLAFQEGLKKHIKLTDEDLKTAWESFHPEVEAQIIQVASEDDAKDVKK
                     AADKGDDFSKLAKDKSTDTTTKEDGGKVKFDSTTTTVPAEVKEAAFKLKDGQVSDVIT
                     STNASTYTTEYYVVKMVKNQNKGNDMDKYKKELKEIATDTKLSDSTFQNKVIGEVLKD
                     ANVKIKDKDFENVLSTFTSDSSTASSK"
     gene            6746..7183
                     /locus_tag="LLC22_001717"
     CDS             6746..7183
                     /locus_tag="LLC22_001717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5434999.1"
                     /translation="MEWFCKFLLFLEVIHVYGFVFLTNKKAGSTMDHLYIKYIHQFSV
                     LVLGTLIIAGIVAFIIQGRDILTVHQEFFSYAFGIPLIAIRSDNKKWKKRYYILLLFL
                     CFYLPPKIFTLLGIQCLSFSFISYIIVLIFLSFIVWMFYLVKK"
     gene            7278..8162
                     /locus_tag="LLC22_001718"
     CDS             7278..8162
                     /locus_tag="LLC22_001718"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family lipid kinase"
                     /protein_id="HBK5435000.1"
                     /translation="MKKVLLVVNPSSGGEQAKEFEQLAIAKLESVFDEVVVLHTKKAG
                     DAKNFTREAATEGYHSVFVMGGDGTVNEGISGIAEQEHRPNFGFFPLGTVNDLARALG
                     IPLEPEEAINHFSIESVKPLDIGKINDDYFMNVVAIGSIPESINDVDAEKKTKFGKLA
                     YFMSGIKQLASTQSYSFHVEVDGKKEEIESSTLLIGLTNSVGGFETLLPNAKVDDGKL
                     HLVYLKDSSLIDTLKTLPDLLKGVDESTKNLAYLTCEQLVVSLADEEELTTNVDGDEG
                     DKLPVTIKVLPSHLQVYC"
     gene            8386..11553
                     /locus_tag="LLC22_001719"
     CDS             8386..11553
                     /locus_tag="LLC22_001719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435001.1"
                     /translation="MNQCVKKLIASILFVFPLLMVTSVFADVEKTNESTQSENQSFDK
                     TTFSEESITSETTESQSEASTNKRQEENKTSETSEVAEQTSDSSEAALARAVSADGYS
                     EAATTEELAQLLADESVTKIRLIQPLTLDRELEIKRDIVIDFGGFAHNFGTHHIYINE
                     IPQSIEFQNFKGTAAHPGGLTPNIDGNAIIIAYMTDFWGSRYHFTGEIKFTGTLDLYD
                     GSKLGLIYAPRATVTLDGVSGVLDVQPVKEGLNAAPGKAYFCRSYQLNVINGSQLYGP
                     YLGKFYGFLDSGDETGSGKTAPGIHILSGSKVSLDYDRADGVSDEGEAVDTLPGNVMF
                     EVSGSGSEFSVNTKINITNDNNRGIIQMRGSGSKVTVSNGGKITINTATTGGFRLQGD
                     SSQIHVSSGGQISVKMAGDDDQPGNNGMRFVGKGLSLIVEGAGSVIDIDKQSGRSSAV
                     RFENGTQKLTVTNGGSLRVRNTGDGKSYVNRLNQGNQAIQFYDASGFLESPGSADFTV
                     TGEKSNIDIRADSGATVDTTGDIDLNFTAGEKTYLVMVGKTGEDKTGIISGDVLNVDL
                     ESPTYFDFQNKRIGSETNGIGGWVFQGNGDSSLKIAHSEIALWRKTGATFDNFEKDPD
                     YFSDMTDLSINGTDLGNFVSSPSAGLTNEFAQTGAGMKNYNRISANNQLPMIESLRVP
                     TNADKKIYGHVVVPEGVEAKPRDAWTGEVEVTLRITYADTTKSSVEITALTQGQTDEN
                     EGAGYNPWGEGEQGGLFEVQVPNDERLKTEDQVQVVAAKKVRGGQEVTELDSAKTTVD
                     VIPPEPANLSTTLINAASRTITGTGEAGALVSLKKNQAVLSETTIDDTGEFVLSIPEN
                     QLFAGDVLEIVLNDQAGEATAKGVQNKPSTNDEIGNHNPSDTPVVYHDAPPFAPATKI
                     VVEGGLSFLAPSKLDFGQIKATGLTQEAFGQMDIQEKLWIYDQRETKNPWILTIKLSQ
                     PFTNDAGFSMQDVLYFKKGEEYQLVNEEELEIVRGQNSTNVQADYSEYLNNGRAFKLV
                     LTKENQIAGNYSAEITWTLADAPTE"
     gene            11573..12118
                     /locus_tag="LLC22_001720"
     CDS             11573..12118
                     /locus_tag="LLC22_001720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014386985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF916 domain-containing protein"
                     /protein_id="HBK5435002.1"
                     /translation="MNRIWNKSHRNNCSLLMILLLGFILWQTPVHASEFNFAVDFELP
                     ANQIDKNKTYINVRMEPGKTQEIPYTVFNRTDKSVTVETLIHSATTNSNGVIEYGESK
                     SKFDETLSYDMKNLAKTVGEITVPPQSAVTETLSLKAPEKELAGVVAGGITFQEKKEN
                     VSNKSTVGVVNQFSQVKAILI"
     gene            12146..12601
                     /locus_tag="LLC22_001721"
     CDS             12146..12601
                     /locus_tag="LLC22_001721"
                     /inference="COORDINATES: protein motif:HMM:NF023225.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3324 domain-containing protein"
                     /protein_id="HBK5435003.1"
                     /translation="MKLKKAYADQSDGRNVIKANLQNPNASYMFGLTTSVEIYKKETK
                     EPYLSIKKEKIDVAPNTNFDLLVPLEGKKLAPGHYQAVVKGAWKEKRWNLHTDFEITD
                     DAADQLNEKDIDLKNQPETFDWRWLILVGVILIGLFAGLFILKERRKKK"
     gene            12598..13356
                     /locus_tag="LLC22_001722"
     CDS             12598..13356
                     /locus_tag="LLC22_001722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WxL domain-containing protein"
                     /protein_id="HBK5435004.1"
                     /translation="MKKTIALSTVLAGSLLLCTQSVFAENKSSATTEGTISVTKPDAA
                     NPEDVVPVPPVDPNDPDTPFTPDEPNQGTSGLLTIDQAPDLDFGTIKLGTAKTVYAAL
                     QSGTDSTGAQTQVQNFVQVTDKSGNYAGWKLSVKRTEFIGTTSDTNKLTGSKVKFKNA
                     VIRNSATNSSGMPSTVSGTGAEGIEIPADQAVDLVTAGANEGIGTWIYSLGENVEQGR
                     QSVELFVPVSNYAVDNYVSTFTWSLTDAPTEEEA"
     gene            complement(13442..14182)
                     /locus_tag="LLC22_001723"
     CDS             complement(13442..14182)
                     /locus_tag="LLC22_001723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5435005.1"
                     /translation="MKKYFIIEDNQFHSEWIIRELVNHHIENIVQLTSISQINQLIQL
                     GTIDNHDVFFIDIDLKQSLTGIDVAEQIRKKNAHSNIVFFTAYTNFAVEIINRKILPI
                     GYIRKDRNLSEQIRQVLEQINWKEQQIVNVDKIFIDQKGGSLVLYPREILYIESIKGL
                     KNQVMVKTTTEDKLVNTSLKQLKTELEKYAYFLLLKSYCINLSQLQKIDSAHYVLEFF
                     NGDSLLVGRKIFEKTKERFHDFQKTASS"
     gene            14243..15496
                     /locus_tag="LLC22_001724"
     CDS             14243..15496
                     /locus_tag="LLC22_001724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GHKL domain-containing protein"
                     /protein_id="HBK5435006.1"
                     /translation="MVATVTLYLTFTLILDLGIYLFFSKQLLVKNSFGCIALMVVTLL
                     LPIPKVSFPYLVGLLLMFLFYFTTKNLFISCLISNLFFAITGLSFFLVFDLMDYLGKR
                     HLGTASFFALLIAFIFYLLVKSIDKQTRFLNLLFTYPTEHYFGGICILLSWGVIYLVL
                     GSVHFRSSNYLLLSLLSIVISFFSLFFSIMLISFQVKERQHQESLQLYQINEEYYHHL
                     EEFKHDYKSLLFSLKITLQENKKETLEFLEILEDHSAAIFEKPQIQQLTNIVSPAVRG
                     VFLKFLEKAESEKIPIQVVIPVEVKTIPIDLVVFIRCLSIFISNAFDHRVADQSPITI
                     NLLEEKEGSRFSIANKANPTNLTLSEMVKRGKTSKKNGGLGLYSAKKMLDVYENAELK
                     IEFSKQNHYFFVEMYLASRKSKSAY"
     gene            15818..16045
                     /locus_tag="LLC22_001725"
     CDS             15818..16045
                     /locus_tag="LLC22_001725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003246265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="winged helix-turn-helix transcriptional
                     regulator"
                     /protein_id="HBK5435007.1"
                     /translation="MLTQQLRELEQDESIHRKAYNQVPPKVEYSLTEEGKSLREILVA
                     LSVWEEERIEKQKASREEDTLLHTHGGYLNY"
     gene            16168..16494
                     /locus_tag="LLC22_001726"
     CDS             16168..16494
                     /locus_tag="LLC22_001726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBK5435008.1"
                     /translation="MNSMEKVNQFRDERNWRQFHNEKDLAISISLEASELLELFQWKT
                     PEEVKETQLERIKEELADVLIYSYMMADNLHLDLDEIIEEKLIKNNLKYPVEKSAGVR
                     KKYTEL"
     gene            16562..17275
                     /locus_tag="LLC22_001727"
     CDS             16562..17275
                     /locus_tag="LLC22_001727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class A sortase"
                     /protein_id="HBK5435009.1"
                     /translation="MKKKGKAKRWLVNILLFLLLLVGLALIFNEQIKDYFVRETGDKY
                     AIANVTKEDLKKNNDKDVSFDFDAVEPMTTEGVMRSQMRGTDLPVIASIAVPSVSINL
                     PVFKGLDNTSLLYGAGTLSPDQEMGKGNYALASHRATNPELLFTPLENLEMGAKIYLT
                     DLENVYTYKTFFKEKVAPTDTQLLNEVEGKEIVTLITCGDMDAVTRLVVQGELESVTS
                     IKDATDDMRSAFNLETKTF"
     gene            17585..18436
                     /locus_tag="LLC22_001728"
     CDS             17585..18436
                     /locus_tag="LLC22_001728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5435010.1"
                     /translation="MKIDKILNNNVVISKNGFGEEVVCMGKGLAFQKKIGDEISPEAV
                     QKEFVLRDSFAKNQFQQLMADIPAEEIEWVKQVVELAEDKLKVEFSPNIYLTLTDHLH
                     YAITRAKENIQLPNPLLFETKKFYPKEYQAAKEALLFVKQKTGVELSEDEAGFIAFHF
                     VNSQQGNEDMQVTMTATTMVRDILSIISKFFGIVFDEESLNYQRIITHLQFFAQRYLK
                     GEGSDEQDEFLYALVQGKYPKAFHCVERINEYLRQTQKQEMGIAEQIYLTIHIQRVVS
                     EKKSIQS"
     gene            18557..20422
                     /locus_tag="LLC22_001729"
     CDS             18557..20422
                     /locus_tag="LLC22_001729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5435011.1"
                     /translation="MDNQAVGRRVWEAVGGQKNVKSLVHCATRLRFRLKDESLADTQK
                     LKEDPDVIQVVQSGGQYQVVIGSNVADVYQSIVDEEGLAVSEDGKEESKNILNRLIDI
                     ISSIFTPFLGAMAAAGVLKGFLSLATVMGWLTADSGTYQILFAAADGVFTFLPVMLAF
                     TAAKKFKANQFLAVAIAMALVYPAITAVAGAGEAISFFGIPVILSPSGYTSSVIPIIL
                     AVWVQSKLEPFVKKVIPQFLQMILVPLVVLVVMVPLTFLALGPIGTVAGNALGGLFNS
                     IYGFSPIVAGLIMGSLWQVFVMFGMHWGFVPIMFLNIEQYGFDVLMPMLLPAILAQGG
                     AALAVALRTKDTKLRALGISSTVTSLFGITEPTVYGVTLPLKKPFIAACISGGIGGAI
                     IGFSGVKAFSSSLVSLLTIPTFINTVDGVESNVTVAVIATGIAFVLAFVGTLILGFDE
                     QTQDNQLENKHANAGEPITSARHTLKSPLTGKVLPLSEVPDQVFSSGVMGKGIAIDPE
                     VGELVAPADGEITTIFPTGHAVGITTTDGAEILIHIGMDTVELNGNGFEILVKQGDLV
                     KAGDLLIRFDIEAIRAAGYSVITPVVITNTDAFADILELDQKEIIANEDVLAIVK"
     gene            20470..21879
                     /locus_tag="LLC22_001730"
     CDS             20470..21879
                     /locus_tag="LLC22_001730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 1 glycosylhydrolase"
                     /protein_id="HBK5435012.1"
                     /translation="MEQLLPNQLEGAYDRDGKGLSVADAMPGGKQRFAIIGSEEFDWT
                     IDQEKYIYPNHRGIDHYDRFKEDLALFAEMGFKCYRFSIAWTRIFPNGDEGTPNEAGL
                     EFYDQLIDECLKYDIEPVITISHYEMPLHLAKEYGGWKNRKLIDFYERFAQTVLERYS
                     SKVKYWMTFNEINSAFHFPALSQGLVKSNGAGEYQNIFQAWHNQFVASSKAVKIGHEL
                     RSDIQIGCMIIYATTYSIDANPVNQAATMIQNQEFNFFCTDVQVRGEYPAYTARTHKK
                     YGVDPEKLEQTEKDFQLLKEYPVDYIGFSYYMSTAINETDPQAATSEGNLLGGVKNPF
                     LEASEWGWQIDPEGLRIALNELYNRYQKPLFIVENGLGAIDHMEEDGTIIDDYRIDYL
                     RRHIEAMANAVADGVDLMGYTPWGCIDLVSASTGEMSKRYGFIYVDLDDEGNGTLNRS
                     KKKSFDWYKEVIASNGVNL"
     gene            21987..22688
                     /locus_tag="LLC22_001731"
     CDS             21987..22688
                     /locus_tag="LLC22_001731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291138.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5435013.1"
                     /translation="MKRTRVLYLEVADKIKEDIFSGKYPVGSMLPTESELEELFQVSK
                     ITVRKAIELLASDEYVAKKSGRGTTVLSNRPYNRLSKAASFTQILENSRYEVRKETLD
                     LQLVHIKKEDPLFSFFGEQAVCFKRLYYLNNQPYIYFVHYLPQEMMQFSREEFGKESL
                     YRLLTKKGYTIDSFSDDFSAVFLTEEEQGILKTDAQIGIKRIRKSSTQIGEMIEYSEA
                     VYHTELHPYHIDYET"
     gene            22847..23326
                     /locus_tag="LLC22_001732"
                     /pseudo
     CDS             22847..23326
                     /locus_tag="LLC22_001732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339057.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIC"
     gene            24174..24749
                     /locus_tag="LLC22_001733"
     CDS             24174..24749
                     /locus_tag="LLC22_001733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00730 family Rossman fold protein"
                     /protein_id="HBK5435014.1"
                     /translation="MKLTVFCGSRFGNKESYKFIAQTLGKYMAQEEIELVYGGSYSGI
                     MGVISKTVLENNGKVTGIYPNGLFETELPGKDVTTFIPTETIDERKVLLFEKGDAVLV
                     FPGGLGTLEEFSQLLSWIAIGLTPDKPIGILNIGGYYSGLQQLLETFAKEDFMDKKWL
                     DQVIFSNNPLELVNELRAVSIKNQLLLKEAK"
     gene            24749..25189
                     /locus_tag="LLC22_001734"
     CDS             24749..25189
                     /locus_tag="LLC22_001734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318723.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside deoxyribosyltransferase"
                     /protein_id="HBK5435015.1"
                     /translation="MSQIYLAGPFFSEEQIDRVSRIEKALEENKTVTSFYSPRHHQES
                     NYELFSAGWAQEVYEKDMEELTNAEFVVAILDFEHQTIDPGTAYELGVATMLKKPMII
                     VQEETVPTNLMITQSLHTYLKSDQAVREYDFETLPVETYVGEYL"
     gene            25205..25906
                     /locus_tag="LLC22_001735"
     CDS             25205..25906
                     /locus_tag="LLC22_001735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336017.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBK5435016.1"
                     /translation="MSVILISGTIGAGKSSLTDMLAKEIDSKPFYENVEDNEVLPLFY
                     SNPEQYAFLLQIFFLNKRFLAMKNALVNDDNVLDRSIYEDSLLFHLNADLGRVTDIEV
                     QQYDSLLDTMLNELDDVAPKKRPDLMVHIKVSLDTMLERIKKRGRDYEQLESDETLYT
                     YYETLNTRYNQWYEDFDVCPKIQVDGDKFDFVENPEDAKKVIRQIQEKLAELEGKPAG
                     KYFTDNQHAKGQELG"
BASE COUNT         8757 a         4214 c         5352 g         7612 t
ORIGIN      
        1 ctacctgtat tagtcctctt ttttgaccag attttgacca gtctatttta cattctaata
       61 tattcatatg agctaatttt atgattaaat ggtaagtgtt tccttgtttg ttttagttta
      121 aactagtgtg taatttaaaa atctatatgg aagggtctgt ggggtaatac ttaaataaag
      181 gctaggaacc tgataacatc aaggttccta gcctttttat aataaaatga agcgaaaata
      241 atttctttta aagagccgag attatcagct atataagagt gaatttgatg caaaaaacag
      301 agccgaaaca gtcttggtgt tcgtagctct gcttatatgt ttcgaattta agacaaagag
      361 ttggcaaaag atgttgataa ggaagataag ataactgtgt tatataaact aggtaactaa
      421 ctgtaacaag ctaattttaa gagattctta ttagaagacg tttaggaata taactaagaa
      481 aatgattata caggtaattg tcatttcaat aatgttttct aattttcgcg tctttgtttt
      541 aagaaaaagg ccagaatcag ttggaaaaaa gttcgtacga tagtgaagag gggcaaaatt
      601 tcctactaat attcccacta acaagagata aaacggccag gttggtgtga ttcctctata
      661 aaaaaatgcc catgctaccg aaatcccata gattaacaac tgaacaattt ttacaatgaa
      721 aaaattgttc tgccattact caaagtctct tcctccttgt atcgtttatt tgtttcattt
      781 tatcattatg ataggcgctt gaacaatcca ttttgtattt tattgagtac tcttggataa
      841 actaccagcg attatcatat ttatttatgt tactgtaagc catcatataa aagtaaatga
      901 gcagatcata gaaatataaa aaagaactaa aattgatcta aattatgtgc agcttgacta
      961 cgtaccaatc tatattactt actagattgg tcgttaatct attcggatcg aatgagcaaa
     1021 atatttttgt gaatgtccat ccttgattat gattccaaaa agaatcattg ggaggctgtg
     1081 gcgtaaatat tatactataa gccagaaata cctatcattc tgaacttttt tatttaggaa
     1141 ctttcatctc aaggcttttt caattaattt gtacccctgt tttttggata agatcatgtg
     1201 cattgatttt ttctatctct acgttcatct cctacttaat gcctatctgg ctcctgaggg
     1261 cttcttttta aggcgtcgtc atagtcttgg ctgaggattt cttggtaatc tgagggaatg
     1321 gcttcccaag tgagcaggcg aacattcatg acgtgttttc ctttgtgttt gattacagca
     1381 tggtttttct ctttttctac ctctccagcg tgaaaagaca gccatgtacc atggccaaag
     1441 atatcattac atacccaacg ttcgatggaa ttgtccacgt atcctacagg gagtgtggta
     1501 tagccgattt gtggtttcaa aaaaggattg aatcgatcga tcgtttcatt tttgtattga
     1561 taattgataa gaaaaagata gaccaaacaa aagacgagca gaaagaaaga tagtgtcttt
     1621 ttgagtgaga agggttgttt tgatgaataa gatttcttgt taacaagagg ttcatctggc
     1681 aatgttggtt ctattgattc ggtagctgat tcaatagaag gaaaatcaat cggcagacct
     1741 aaagtatgat gtaaaagtga cagcatttca aggtctggca ttgtacgaga attttcccaa
     1801 ctagaaatcg ttttatcgga aacaccaatt ttttcgccta attctttttg cgtaagctta
     1861 caatttctgc ggtaagttcg tattttttct ccggtgttca tcttcttctc ctttcgattc
     1921 tacagtatat agatttattc tacatgacct atacacttga tagatacgtt tttttgatga
     1981 aaaacggtat gattttatca aagaatcatt taagtaaggg agagtggtga taatcaaaaa
     2041 aaagttcaca gttttactca caatcatagt gaccggtatc atgagtggtt ttgccttggt
     2101 tagtataaat aaacaggtac tctatcggac aaatgaattt ttccatcaaa cagatactta
     2161 tactccgatt cgattgccac aacattttat tgggcaagaa gaatatgagc agctaatcat
     2221 ggtatttgaa aatgtctcat cagaaactga gctttcttat atgaaaaaaa cagtaaatga
     2281 atccaatgaa gtagatacat cttggaactt caagatacag ccaaagcttg aaatgacatt
     2341 gtattatcaa ggggatgtca aatcttctca cgagaaggta ccctattcta atacctcctt
     2401 tcgcgtaacg tccattgaag aatcgatcaa aataaaagat tttgaaggtg aatttttctt
     2461 gatgacgaga gaaaaagaag cctatgaacg gttcatttca ctattcactg atcgattcaa
     2521 tcaagcattt cacactgatt atgccactaa tatttttgaa gactttgaaa atagctattc
     2581 gtattcggtt atttcaaata cagacgtata taattatcga gtgtatttaa ctattggatt
     2641 gattctttta ttccttttgt tatcatcctt tttcttattg atgaataaag aaatcagttt
     2701 attgttgaat aatgactttt cattacatca agtattgtgg tgtttattgg ggaaaaagaa
     2761 aatcattatt acattcataa ttgcaggaat cattggtggt tttattttta tgtattataa
     2821 ggagcaattt ctttatttgt tccagatgta cgttttcttg ttcagcggaa tatatggtat
     2881 ctctttgatt tctcttttat tagttgaaaa aatcgcttcg ttaagagaag cgttcaacta
     2941 tatccaatac attcttttta catttggatt gttgttttct cttcttttga ccgttgccaa
     3001 tgtcgaatta gcaactatcg ttttttcttc ttcacagtta gctgtttccc atgaaccacc
     3061 aaaagaaatc gctggtgagg actatcatgt attttatcca gtaaccatcg ggaaaaacca
     3121 cgtggatttt atttattcca atcgttttgc atcagcagca gatcaggaat tatatgaaac
     3181 tttgaataaa aacggaagta tattagtcaa tgtatcagat tacttgaatg aagaaaatga
     3241 acagtttggc agagggataa aaataaatct gaattatctt aagaaatttc ctttgattga
     3301 tgtctctgga aggttgatcc aaataaccga aaaagaaacg caccctgtta tattgatccc
     3361 tgaacgatat agacatacag atttaaaaaa tgacctggcg caaataacag aatattatca
     3421 agaaatcagt gaaaaagaac cgaaatttct atttataaaa aacaatcaac ccatttatac
     3481 atttattcct tctatcccct ggatcgaaca ttatccggtt gttgaaatac tgacattgaa
     3541 aaacagtatg tatttggaaa gaaatattct cagcggagaa atctatccac cgttaaagat
     3601 caagataggc tctttgtcga aagaaaggtt atttgagctg attgaagaaa gtcagttacg
     3661 tgataacttg cagttatcat ttccgtatac tcagactgaa gagatagctg tcaaagtgtt
     3721 aagcagatca tttcattact tgatacagat atttttactc actttctttt ctttcttctt
     3781 gttgagctat gtcatgttat gcatatattt tgtctacaat tgtcggaaaa tcgctatctt
     3841 tcgttcaagt ggttattcgc tctttgaaac gtataaagat ttcttcatga tgaacctcat
     3901 caaatgggga acgacaagtg taatcttcct ttttcttata gaaagagagc ctaaatatct
     3961 ttttaatatt tttttcttta gcttcattga ttttattctt tcagttgttt ttattttgtc
     4021 tacagaaaag aaaagtcagt tattgctgat gaatggaggt taacaattgg agccgttgat
     4081 agtgataaaa ggtgcgaaaa aaatcattcg aaacaaaacg attcttcatt tggatcgttt
     4141 cactgcggat gctggggatc ttgtgactgt tgttggagaa agtggagcag gtaaaagtac
     4201 gttattgaat atattaggat tgaatgatca gttcagttca ggacaattct atttgttcga
     4261 tcaagagacg aaacaattaa ctgggagaga gaagcgcttg ataaaaagaa ataccatatc
     4321 ttttcttttt caagattttg ggttgattga atatgaaaca atcgatttta atttagatat
     4381 tggattgaag ttttcgaatt taaatgtttc agataagcga acagcaaagt atgaggcatt
     4441 gaaaaaagta aatataaaca agaagctaag tacgcctatc tacacattat ctggtggtga
     4501 gaagcaaaga atcgcctgtg cgagagtctt attgaagaat agcaaaatca ttttagccga
     4561 tgaaccgact gggtcattgg ataaaagaaa taaggataaa gtagttgaaa tcttatcgca
     4621 acaagcttcc caaggtacgt tagttatcgt agtcacgcat gatccatatc tgaccaaaat
     4681 aggaaacaag aagatcatgc tttaaaaatc aaaaaggaaa ggatgtcgtt ttatgaaaaa
     4741 agcagttatt atttgtgcac tagggatagg ttttgttgga ggaaacgcta tgtcatctga
     4801 agtggaagca aattcagttc acggtgaaat ctattacaaa tctttaaagc caggagagat
     4861 tcattttgat gctaaaggta atattattaa gtcaaattta ccagtagacc gggaaatttc
     4921 tagaacagca attaatcata gctctggaag atgggtttat tatagtgata caacttgtac
     4981 gagaaaaaca ggtcattcta accactatag tcgtgtctat aatcgtcacg gtgcaaaaga
     5041 gaaagttgga aactctattc gatcagcaaa tgcaacaaaa ggagtatggg cctatgcaag
     5101 tgcgacagga aatagaactg acacattctc atgttggtac aatccaaccg gttggtatta
     5161 agtatccaaa agtttatata aaatagaaaa aacatataat gaaacagcgt taaaagttat
     5221 ttttggtagt tttaatatat tcatttttag ttgtataaaa atatatcata ataaaaacaa
     5281 caaaaaaatg tctggaaaat cgaacataaa agtgtctgat ttgaatatcc cagcagcgga
     5341 agaagaaaaa caaaatcgat aacatttgtt ctaagaatta gttacgttaa atacggaacg
     5401 caagatagac ttgaaaaacg gtaacaaaag aagtagtata ttaaggtgtg atgtgctact
     5461 tgacatttat tctgctgagc gaactttctg gattgtgtag ccttatatct attcaggacg
     5521 tatcgagcag attagtaaag gtgttcttga tgattttcat cttgaacacc tttgttttta
     5581 gcaattcgca aaaaacgaaa agtaggagaa ttgataaatg aaaaaaagat ttttagcact
     5641 tgccatcgta ctaggcactg gcttattgtc aggctgtacg aatgccggtg aaaaaacagc
     5701 cgttagttat aaaggcggta caatcagcga acaagaagta atggatagct tgaaaaaaat
     5761 gcaaggagca gattccgctg tgcaacagtt gatcgtttat caagtatttg aagataaata
     5821 tggagatgac gtatcaacca aagaaatcga ttctcaatat gatcaaacaa agaaacaatt
     5881 gggtgattca tttgattcac aattgaaatc tgcaggttac acagaacaaa cattcaaaga
     5941 cagtatcaaa caaagtctag cctttcaaga aggtctaaag aaacatatca aattgaccga
     6001 tgaagattta aaaacggctt gggaatcttt ccatccagaa gtggaagctc aaattatcca
     6061 agtagcaagt gaagatgatg caaaagatgt gaagaaagct gctgataagg gagacgattt
     6121 ctctaaatta gccaaagaca agtcaactga tactacgaca aaagaagatg gcggaaaagt
     6181 gaaatttgat tccactacta caacggttcc ggcagaagtc aaagaagcag cctttaagtt
     6241 gaaagatggt caagtttctg atgtgatcac ttctaccaat gcttcaactt atactacgga
     6301 atattatgtg gttaaaatgg tgaaaaacca aaacaaaggc aacgacatgg ataaatacaa
     6361 aaaagaattg aaagaaattg caacagacac aaaattaagt gacagtacct tccagaataa
     6421 agtaattggc gaagtattga aagacgctaa tgtaaaaatc aaagacaaag actttgaaaa
     6481 tgttttgagt acattcactt cagattctag tacagcaagt agtaaataag cggtataaat
     6541 aaaaaatatg aactatttaa atcaataaaa ctgttcatct aaatcttttt attagaacta
     6601 aatcaacagt agtttaatta ctacttgatt tagttctttt tattttaaaa atttttttta
     6661 cttagaatcc agcgacccta gatatttttc tgtataatct taaataaaga aaacaatatc
     6721 aaaaaatgca cgtagaagta gataaatgga gtggttttgc aaatttcttt tatttctaga
     6781 agttattcac gtatacggat ttgtttttct cacaaataaa aaggcaggaa gtacaatgga
     6841 tcatttgtat ataaaatata ttcatcaatt ttccgttttg gtgttaggca cactaattat
     6901 agcggggatt gtcgcattta ttattcaagg ccgtgacata ttaacagtac atcaagagtt
     6961 tttcagttat gcatttggta ttcctctgat cgctataagg tctgataaca aaaagtggaa
     7021 gaaacgctat tacattctct tgctattttt gtgtttttat ctgccaccta agatttttac
     7081 tttattaggt atacaatgcc tatcattttc ttttatttcc tatatcattg ttttaatttt
     7141 cctcagtttc atagtatgga tgttttatct tgtcaaaaaa taaatgaatg tttcatgaac
     7201 agtacttcat cacagcctaa tttttttctt tatgctatcg ttatattaaa gaaatcaatc
     7261 agaagggaaa gaaagtgatg aaaaaagttt tattagtggt aaaccccagt tcaggcggtg
     7321 aacaagcaaa ggaatttgag caattagcga tagcaaaatt ggaatcggtg tttgatgaag
     7381 tggtcgtctt gcatacaaaa aaagcagggg atgcaaaaaa ctttactcgc gaagcggcta
     7441 cggaagggta tcatagtgtg tttgtcatgg gcggagatgg aacagtcaac gaaggaatca
     7501 gtggaatcgc tgaacaagaa catcggccaa atttcggatt tttcccattg ggtacggtga
     7561 atgacttggc tcgagcatta gggataccgc tagaacctga ggaagcgatc aatcattttt
     7621 cgattgaatc agtcaagcca ttggatattg gaaaaataaa tgacgactat tttatgaatg
     7681 tcgtcgcaat tggctctatc cctgaatcaa tcaatgatgt agatgcggag aagaagacga
     7741 aatttggaaa actagcttat ttcatgtcag gaatcaaaca gttagcttcc acacaatcct
     7801 actcgtttca cgtagaagtt gatggaaaga aggaagaaat tgagagcagt accttgctga
     7861 taggactaac taactcagtc ggcggttttg aaacattact tccaaatgca aaagtggatg
     7921 atggtaagct ccatttggtt tatttaaaag attcttcttt gatcgatacg cttaaaacat
     7981 tgccagacct attaaaagga gtagatgaat ctacgaaaaa tctagcctac cttacttgtg
     8041 agcaattagt tgtgtcatta gctgatgagg aagaattgac gacgaatgtt gatggagatg
     8101 aaggggataa attacctgtg acaatcaaag tattgccctc acatttacag gtttattgtt
     8161 aaaatggagg ttgtgaccga ggagttggcg ggagaacacc gcttgttcgg gataagggac
     8221 tgtgacaaga cttttgtcac agcctttttt ttgtacaaaa aagaaattta cacctaatag
     8281 aaaaattttt ccataaaaat acatatttta aatatgaaag tacaattgga aatagattaa
     8341 aacgataaaa taaaattgtc aaaacgtcag agaggatggt ggagaatgaa tcaatgtgta
     8401 aaaaagctga ttgcgtcgat tttgtttgtc ttccctctct tgatggtgac atccgttttt
     8461 gccgatgtag agaaaacaaa cgaatcaacg caatcagaga atcaaagttt tgacaagact
     8521 actttttcag aagaatcgat tacttctgaa actacagaat ctcaaagtga ggcttctact
     8581 aataaaaggc aagaagaaaa taagacaagt gagacctcag aagtagctga acaaacgtct
     8641 gatagcagtg aagcggcact ggcaagagct gtttcagcgg atgggtacag cgaagctgcc
     8701 acaacagaag aactggcgca gcttctcgca gacgaatcag taactaagat ccgactgatt
     8761 cagcctttga ctttagacag ggaattagag atcaaacgag atatcgttat tgattttggt
     8821 ggattcgctc acaatttcgg cacacaccat atttatatca atgagatacc tcagtcgatc
     8881 gagttccaga attttaaagg aacagctgca catccaggtg gattgacacc aaatatcgat
     8941 ggaaatgcca ttatcattgc ttatatgacc gatttttggg gaagcagata tcattttacg
     9001 ggagaaataa aatttaccgg gacacttgat ttgtatgatg ggtccaaatt aggactgatt
     9061 tacgctcctc gtgcaactgt cacattagat ggtgtttccg gtgtgttgga tgtccaacca
     9121 gtgaaggaag gactgaatgc cgctccgggt aaagcctatt tttgtagaag ctatcaattg
     9181 aatgtgatca atggtagtca actttatgga ccgtatctag ggaaattcta cggttttcta
     9241 gattcaggag atgagactgg tagtggaaaa acagcgccag gaatccatat cttaagcggt
     9301 tcaaaggtct ctcttgatta tgatcgggca gatggcgtta gcgatgaagg agaggcagtc
     9361 gatacgctac ctggtaatgt catgtttgaa gtcagtggtt cgggaagcga attttcggta
     9421 aatacaaaga tcaatattac caatgacaac aatcgcggaa tcatccaaat gagaggttca
     9481 ggatcgaaag tcactgtatc gaatggtggg aaaatcacca tcaatacagc aactacgggc
     9541 ggatttcgct tgcaaggaga ttctagtcaa atccatgtat caagtggtgg acaaatctcg
     9601 gtcaaaatgg ctggagatga cgatcaaccc gggaacaatg ggatgcgttt tgtaggaaaa
     9661 ggcctttctt tgatcgtaga aggagccgga tcagttatcg acatcgataa gcagagtggg
     9721 cgttccagcg cagttcgttt tgagaatggt acgcaaaagc tgacagtaac caatggaggc
     9781 tcattgaggg taagaaatac aggtgatggc aaatcttacg tgaacagact caatcaagga
     9841 aatcaagcga tccaatttta tgacgcttct ggttttctag aaagtccagg ttcagctgat
     9901 tttacagtca ctggagaaaa atcaaatatc gatatacgcg cagattccgg agcaactgta
     9961 gatacaactg gagatattga tttaaatttt acggcaggtg aaaaaactta tttagtcatg
    10021 gtcgggaaaa caggggaaga taagaccggc atcatcagtg gggatgtgtt gaatgtggac
    10081 ttagaatctc ctacctattt tgatttccaa aacaaacgga ttggaagcga gaccaatggc
    10141 ataggcggct gggtattcca aggaaatgga gattcttctt taaagatcgc ccattcagaa
    10201 atcgctttat ggcgaaaaac aggcgcaaca ttcgataact ttgaaaaaga cccggattat
    10261 ttttctgata tgacagactt atcgatcaat gggaccgact taggcaattt cgtatcaagc
    10321 cctagtgcag gtttaacaaa tgaatttgct cagacaggtg ccggaatgaa aaattataat
    10381 cgaatcagtg ccaataatca gctcccgatg attgaatcct taagagtgcc aacgaatgca
    10441 gataaaaaaa tctatgggca tgtcgttgtt cccgaaggtg tcgaggcaaa gccaagagat
    10501 gcttggacag gcgaagtaga agtgacttta cgtattactt acgcagatac gacgaaatca
    10561 tctgtagaaa ttactgctct cacgcaagga caaacagatg aaaatgaagg ggcaggatat
    10621 aacccatggg gagaaggcga acaaggcggc ttgttcgaag ttcaagtacc caatgatgag
    10681 agattaaaaa cggaggatca agtgcaagtt gttgctgcta aaaaagtaag aggtggccaa
    10741 gaagtgacag aactggactc tgccaaaacg acagtcgatg tgattcctcc tgaacctgct
    10801 aatttaagta ccacattgat caatgcagct tctcgcacga tcacaggtac aggtgaagca
    10861 ggagccttgg tttcattgaa aaaaaatcaa gctgttttgt cagaaacaac tattgatgat
    10921 acaggggaat ttgttctttc tatcccagaa aatcaacttt ttgcaggaga tgtattagaa
    10981 attgtattaa acgaccaagc aggagaagct actgctaagg gtgtgcagaa caagccaagt
    11041 accaacgatg aaattgggaa tcacaatcca agtgatacgc cagttgttta tcatgatgcc
    11101 ccgccttttg cacctgctac gaagatcgta gtagaaggtg gtctctcatt tcttgcccct
    11161 tccaaactcg attttggtca gatcaaagca actggtttga cacaagaagc atttggccaa
    11221 atggatatac aggaaaaatt atggatttat gatcagcgag aaacgaaaaa tccgtggatc
    11281 ttaacgataa aattatctca gcctttcaca aatgatgcag gattttctat gcaggatgtc
    11341 ctatatttca agaaaggaga ggagtatcaa ttagtgaatg aagaagaact ggaaattgtc
    11401 agaggacaaa attcaacgaa tgtgcaagca gattattcag aatatttaaa taacggtcgg
    11461 gcgtttaaac ttgtcttaac caaagaaaat cagatagctg gtaattactc agcagagata
    11521 acatggacat tagcagatgc gccgacagaa taaagatcaa ggaggatgat tgatgaatcg
    11581 aatatggaat aaaagtcatc gaaacaactg ctctttactt atgatccttc tccttggatt
    11641 catcctttgg cagacacctg tccatgcctc cgaattcaat tttgcggtag attttgaatt
    11701 accggctaat cagattgata agaacaaaac atatataaat gtaaggatgg agcctgggaa
    11761 aacacaggaa atcccctaca cggtctttaa ccgaacagat aaatcagtaa cagttgagac
    11821 attgatccac tccgctacga cgaattcaaa cggtgtgatc gaatatggag aatcaaaaag
    11881 taaatttgat gaaacattaa gttatgatat gaaaaactta gcaaaaacag tgggagaaat
    11941 aactgttcct cctcaaagtg cggtcactga gacactttca ctgaaagcgc cagaaaaaga
    12001 gctggctggt gtggtcgcag gagggatcac gtttcaagaa aaaaaagaga acgtttctaa
    12061 caaaagtaca gttggtgtcg tcaatcagtt ttctcaagtg aaagcaatct tgatttgaaa
    12121 tagcgaaaaa gagtcttccc cagatttgaa attaaaaaaa gcttatgcgg atcaaagcga
    12181 tggaagaaat gtgattaagg cgaatcttca aaatccaaat gcttcttata tgttcggctt
    12241 gactacatcg gttgaaatct acaaaaaaga aacaaaagag ccttaccttt caataaaaaa
    12301 agaaaaaata gatgtagcac ccaatacaaa ttttgattta cttgtcccat tagaaggaaa
    12361 aaaattagct ccgggacatt atcaagcggt tgtgaagggt gcttggaaag aaaaacgctg
    12421 gaatctccat accgattttg aaataactga tgatgcagcg gaccaattga atgaaaagga
    12481 tattgattta aaaaatcagc cagaaacatt tgactggcga tggctgatac ttgttggagt
    12541 cattcttatt ggcttatttg ctggattatt tattttaaaa gaaagaagga aaaagaaatg
    12601 aaaaaaacaa ttgcattaag taccgttcta gctggaagtc tattattatg tacacaaagt
    12661 gtttttgctg agaataagag ctcagccact acagaaggaa cgatttctgt gaccaaacca
    12721 gatgctgcaa atcctgaaga cgttgttcca gttcctcctg ttgatccaaa tgatcctgat
    12781 actcctttta cacctgacga accaaatcag ggaacatccg gattactgac gattgaccaa
    12841 gctccagatc ttgattttgg aacaatcaag ttaggtacag caaaaacagt atatgctgca
    12901 ttacaaagcg gaacggacag tactggagca caaacacaag tacagaattt cgtacaagta
    12961 acggataaaa gcggaaatta tgccggttgg aaattatcag tcaaacgaac agaatttatt
    13021 ggtacaacat ctgatacgaa taaactaact ggttcaaagg tgaaattcaa aaacgccgtg
    13081 attcgaaata gcgcaactaa tagcagtgga atgccatcta ccgtttctgg aactggcgct
    13141 gaaggaatcg aaatcccagc agatcaggca gtagatctag taactgcagg agcaaatgaa
    13201 gggattggca catggattta ttcattagga gagaatgtgg aacaagggag acaatcagtg
    13261 gaattatttg ttcctgtatc caattatgct gtagacaact acgtttcaac attcacatgg
    13321 tcgttaacag atgctcctac agaagaggaa gcgtaaaatc atatcaacga tttcagggag
    13381 tggagccgat tcaaggccca ctccctgaaa tctgctatgc ttacgtctca gctcttattc
    13441 atcaactcga agcagttttt tggaagtcat ggaaacgttc ctttgtcttt tcaaagatct
    13501 ttcgaccaac gagtaaggag tcaccgttga aaaattctaa cacataatga gcagaatcaa
    13561 ttttctgcaa ttgcgataag ttgatacagt aagattttaa aagtaaaaag taagcatact
    13621 tttctaactc tgtcttcaat tgttttaaag aagtattcac taatttatct tctgtagttg
    13681 ttttgaccat aacttggttt ttcaaacctt tgatactttc aatatataaa atttcccgag
    13741 gatacaggac gagacttcca cctttttgat caataaagat tttatcgaca tttacgatct
    13801 gctgttcttt ccaattgatc tgttctagca cttgacgaat ttgttcagat aaattcctgt
    13861 cttttctgat atatccaatc ggaaggattt tccgattgat gatctctact gcaaaattcg
    13921 tataagcggt gaaaaaaaca atattactat gtgcattttt tttacgtatt tgttcggcga
    13981 catcaatacc tgtgagtgat tgcttcaagt cgatatcgat aaagaaaaca tcgtgattat
    14041 caatagtgcc caactggatc aactgattga tttgagagat agaagtgagc tgcacgatat
    14101 tctcgatatg atgattgacc aattctctga tgatccattc gctgtgaaac tggttatctt
    14161 ctatgataaa atactttttc atatgcaggc tcctattaaa aaaatatgtg tacattttga
    14221 aacaaaacaa tggaggaata agatggtcgc aacagtgaca ctttatttga cctttacttt
    14281 gattttagat ttaggtatct atttattctt ttcgaaacaa ctgctagtaa aaaacagctt
    14341 tggttgtata gctttgatgg tggtgacact tttacttcct atccctaaag tgagctttcc
    14401 ttacctagtt ggcttattat tgatgtttct tttttatttt actacgaaaa acctgtttat
    14461 cagctgtttg atcagtaatc ttttttttgc tatcactgga ctcagctttt ttctggtttt
    14521 tgatctgatg gattatttag gaaagagaca tcttggaaca gcaagttttt ttgcactact
    14581 tatcgcattt attttctatc tattagtaaa aagtatagac aaacagacga gatttctcaa
    14641 cttgcttttt acttatccaa ctgaacacta ttttggaggt atttgtattt tattaagctg
    14701 gggcgtgatt tacttggtat tgggaagtgt tcacttccgc tcatctaatt atctgcttct
    14761 atctcttttg tcgatagtca tcagtttttt ttctttgttt ttttccatta tgttgatcag
    14821 tttccaagta aaagaaagac aacatcagga atcgcttcaa ctgtatcaaa taaatgaaga
    14881 atattaccat catctagagg aattcaaaca tgattataaa agtctactgt tttcattaaa
    14941 aattactctt caggaaaata aaaaagaaac gttggaattt ttagaaatat tagaagatca
    15001 ttctgcagct atttttgaaa aaccgcaaat acaacagcta acaaatattg tatccccagc
    15061 tgtcaggggt gtctttttaa aatttctaga aaaagcagaa tcggagaaaa tcccgatcca
    15121 agtagttatt cctgtcgaag tgaaaacaat cccgattgat ctggttgttt ttattcgctg
    15181 tttatctatt tttatttcta acgcattcga tcatcgtgta gccgatcaga gtccgattac
    15241 gatcaatctg ctggaagaaa aagagggatc acgttttagt atagcgaaca aggcaaatcc
    15301 aacgaatttg acgctatcgg agatggtcaa aagaggaaaa acctctaaaa aaaatggcgg
    15361 gttaggtcta tacagtgcga aaaaaatgtt ggatgtttac gaaaatgcag aactaaaaat
    15421 cgaattttca aaacagaatc actatttttt tgtagaaatg tatctggcat ctagaaagag
    15481 caaatcagcc tactgactta ctgtcaaagg ataagtttga ggaaagtcta cacggagata
    15541 gagacaacaa cacagcatat tcaaaagaaa cagaagcgtg atgaccgttg tcacccttct
    15601 gtttcttttg ctatgtagtt aaacaaagta gttgacactt ccgctactta gtattagtac
    15661 gaaagtatac ttcatgatac taagtagata agaagtgaaa agcggaaccc acgatcgtca
    15721 aaatgctaac tgctttgctt acaccagata aagggaagag caatatcgct tattttaggc
    15781 gtggagaagc aagcaaatcc ctacgatcac aaaaaaaatg ctgacccagc agttaagaga
    15841 gttagaacaa gatgaaagta tccatcgaaa agcctataac caagtcccgc ctaaagtaga
    15901 gtactcgctc accgaagaag gaaaatcatt aagagagatt ctagtagcgt tgtctgtttg
    15961 ggaagaagaa cgtatcgaaa aacaaaaagc ctcaagggaa gaagacacgc tactgcatac
    16021 acatggtggc tacctaaatt attgattttc tatgacattt attttaaata aaagaaaaca
    16081 ggagtttttt taaaagcatc atctattttt tatgtaaaaa aatggtatga ttaatcaagt
    16141 aagaagtgat tggaagaagg caagcaaatg aatagtatgg aaaaagtcaa ccagtttaga
    16201 gatgaacgta attggcgaca atttcataac gaaaaagatt tggctatctc tatttctttg
    16261 gaagcatctg aattgttaga actttttcaa tggaaaacgc cggaagaagt aaaagaaaca
    16321 caattagaac gaatcaaaga agaactggca gatgtattga tctattcata catgatggca
    16381 gacaaccttc acctggatct agatgagatc attgaagaaa aattgatcaa aaataatttg
    16441 aaatatcctg tagaaaaaag cgcaggtgta cgaaaaaaat acacagagtt gtagaaatgt
    16501 gtcattcggc tgttggaaag agcaaaagaa aaacagtaaa atgagtctgg agggagagaa
    16561 aatgaaaaaa aaaggaaaag caaaaagatg gctagtcaat atcctcttgt tcctcttgtt
    16621 attagtagga ctagctttga ttttcaatga acagatcaag gattattttg tcagagagac
    16681 aggagataaa tatgctatag cgaatgtaac aaaagaagat ctgaaaaaga ataacgataa
    16741 agatgtcagt tttgactttg atgcggtaga accaatgacg acagaagggg tcatgaggtc
    16801 gcaaatgaga ggaacagatc taccagtgat tgctagtatc gcagtccctt cagtttcaat
    16861 caatttaccg gttttcaaag gcttggataa tacgtcacta ctttacggag caggaacatt
    16921 atctccagat caagaaatgg gaaaaggaaa ttatgcctta gcaagccatc gtgcaacgaa
    16981 ccctgaattg ctgtttacac cgctagaaaa tttagagatg ggtgccaaga tctatttgac
    17041 agatttagaa aatgtgtata catacaaaac attttttaaa gaaaaagttg ctcctacaga
    17101 tacccaatta ctgaatgaag tcgagggaaa agaaattgtc acactaatta cttgtggcga
    17161 catggacgcc gtcacgcgac tagttgtaca aggagaactg gaaagtgtta catcgataaa
    17221 agatgcgaca gatgatatga gatctgcttt caatctagag acaaaaacat tttaggatac
    17281 tgggacataa gtcgttacag attaaaaaca gccaaaggat atgaatcgat aaggaaaaac
    17341 caatttgctg aaaaaaagag aaacgcaaag aggtgcatct ctgatttggt tgttttctag
    17401 atagacttgt gttccagttt ttttattttt tatatgaaaa ggcttgcata aataaaaatt
    17461 cgatggtatg atgattttga ataagaaatg gattgttact gtacggcagg caaaaccaga
    17521 attcagctaa gaaacagtag gcgaattcta ggttttttta tttttcttga gagggcgaag
    17581 caaaatgaaa attgataaaa ttttgaataa caatgtcgtc atttcgaaaa atggattcgg
    17641 ggaagaagtc gtttgtatgg gaaaaggact agcttttcaa aaaaagattg gggacgagat
    17701 ttcgccagaa gcggtccaaa aagaatttgt tttaagagat tcttttgcta aaaaccaatt
    17761 ccagcagctg atggctgata ttccggcaga ggagatcgaa tgggtcaaac aagtagtcga
    17821 actggctgaa gataaactaa aagttgaatt ttcgcctaat atttatctga cattgaccga
    17881 tcatcttcat tatgcgatca cacgagcaaa agaaaatatc caactgccta atccattatt
    17941 atttgaaaca aaaaaatttt atccgaaaga atatcaagca gcgaaagagg ctcttttgtt
    18001 cgtgaaacaa aagacgggtg tggaactttc tgaggatgaa gccggtttta ttgcctttca
    18061 ttttgtgaat agccaacaag gaaacgaaga catgcaagtg acgatgaccg ctaccacaat
    18121 ggtaagagat atactgagta tcatcagtaa attcttcggc atcgtgttcg atgaagaatc
    18181 tttgaattat cagcgtatca ttactcatct gcagtttttt gcccagcgtt atctcaaagg
    18241 ggaaggatct gacgagcaag atgaatttct ctacgcatta gttcaaggaa agtatccaaa
    18301 agcgtttcat tgtgtcgaac ggatcaatga gtatcttcga caaacgcaaa aacaggaaat
    18361 ggggatcgca gagcagattt atttaacgat tcatattcaa agagtagtaa gtgagaaaaa
    18421 aagcatccaa tcataaggat tgttactgta tggcaggcaa aacctggatt gaaaaaatag
    18481 gttcacgaat gtttgtgact gtttttttca atctgggttt ttatttttta aataaaaaag
    18541 aaagaaggaa aaaacaatgg ataatcaagc agttggtcgt cgtgtatggg aagcggtagg
    18601 aggacaaaag aatgtcaaaa gtttagtaca ttgtgctacg cggttgcgat tcagattaaa
    18661 agatgaatct ttagcagata cgcaaaagtt aaaagaagac ccggacgtga tccaagtcgt
    18721 acaaagtggc ggtcagtatc aagtagtgat tggcagtaat gtagcagatg tttatcaatc
    18781 gatcgtggat gaggaaggtc ttgcagtttc ggaggatgga aaagaagagt ccaaaaatat
    18841 tttgaatcgt ctgatcgata ttatctctag tatatttaca ccttttctag gggcgatggc
    18901 agccgccggg gtattgaaag gattcttatc attggcaacg gtgatgggct ggctgacagc
    18961 tgatagcggt acttatcaaa tattgtttgc tgcagcagat ggtgtcttta ccttcttacc
    19021 tgtcatgctt gcttttacag cagctaaaaa gttcaaagcc aaccagtttt tagcagtagc
    19081 aattgctatg gcacttgtgt atccagctat cacagcagtt gctggtgcgg gagaagctat
    19141 cagtttcttt gggatcccag tgattctttc accatctggt tatacttctt ctgtcatacc
    19201 aatcattcta gccgtatggg ttcaaagtaa attagagcca ttcgtaaaaa aagtgattcc
    19261 gcaatttctg caaatgattt tagttccgct tgtcgtttta gtagtgatgg ttccattaac
    19321 atttcttgct ttaggaccaa tcgggacggt tgccggtaat gctttaggcg gtctcttcaa
    19381 ctcgatttat ggatttagtc caatcgtagc aggtctaatc atgggaagtt tatggcaagt
    19441 attcgtgatg ttcggcatgc attggggatt cgtaccgatc atgtttttga atatcgaaca
    19501 atatgggttt gatgtattga tgccaatgct tcttccagcc atcttggcac aaggtggggc
    19561 tgctttagct gtagcattgc gaacaaaaga tacgaaactt cgagcattag ggatttcttc
    19621 tacagtgact tcgttatttg gaatcactga accaactgtg tatggtgtga cattaccttt
    19681 gaagaaacca ttcattgccg cttgtatttc tggaggtatt ggtggagcta ttatcggatt
    19741 ttccggagta aaagctttct ccagcagttt ggtcagctta ttgacgattc cgactttcat
    19801 taatacggtg gatggtgtag agtcaaatgt gacagtagca gtaatagcta caggaattgc
    19861 ttttgttctt gcattcgtag gtacattgat tttaggattt gacgaacaaa cacaagacaa
    19921 tcaattagaa aacaaacatg cgaatgcagg agaaccgatt acttcagcac ggcatacctt
    19981 aaaaagtcct ttaacgggta aagtactgcc attgagtgaa gtaccagacc aagttttttc
    20041 ttctggcgtg atgggaaaag gtatcgctat tgatccagaa gtaggagaac tagttgcacc
    20101 tgcagacgga gagatcacga ctatttttcc aactggacat gctgtaggga tcacaacgac
    20161 tgacggagcg gagattttga ttcatatcgg gatggataca gtagaattaa atgggaatgg
    20221 ctttgagatc ttagtcaaac aaggggatct cgtcaaagca ggagatttat tgattcgttt
    20281 tgacatcgaa gcaattagag cagctggcta tagcgtaatc actccagttg tcattacgaa
    20341 tactgatgca tttgccgata tacttgaatt agaccaaaaa gagattattg caaacgaaga
    20401 tgttctggca attgtaaaat aaggaggaaa tcaggatgca atcacgtttt tcagaaaaat
    20461 ttttatgggg tggagcaact gctgccaaat caattagaag gggcttatga tcgagacgga
    20521 aaaggactat ccgttgcaga tgctatgcct ggaggtaagc agcgctttgc gattatcggc
    20581 agtgaagaat ttgactggac gattgatcaa gaaaaatata tttacccgaa tcatcgagga
    20641 atcgatcatt acgatcgttt caaagaagat cttgccttgt ttgcggaaat gggattcaaa
    20701 tgttatcgtt tttcgattgc ctggacacga atttttccaa atggagacga aggtactcct
    20761 aacgaagcgg gattagaatt ttatgatcag ctgattgatg agtgcttaaa atatgatatt
    20821 gaacctgtga tcacgatttc tcattacgaa atgcctcttc atttggcaaa agaatacggt
    20881 ggctggaaaa atcgaaaact gatcgacttc tatgaacgat ttgctcagac agtattagag
    20941 agatacagca gtaaagtcaa atattggatg actttcaatg aaatcaattc ggcctttcac
    21001 tttccagctt taagtcaagg attagtaaaa agcaatggag caggagagta ccaaaatatt
    21061 ttccaagcat ggcataatca attcgttgca agtagcaaag ccgtaaaaat cggccacgaa
    21121 ttgcgttcgg atatccaaat cggctgcatg attatctatg caacaactta cagcatcgat
    21181 gccaatccag tcaatcaggc agcaacaatg atccaaaacc aagaattcaa ttttttctgc
    21241 acggatgtcc aagtacgtgg agaataccct gcatacacag cgcgtaccca taaaaaatat
    21301 ggagtcgatc cggaaaaatt agagcaaacg gaaaaagact tccagttgct aaaagaatat
    21361 ccagtggact acatcggatt tagttattat atgtctacgg caatcaatga gactgatcca
    21421 caagcagcaa cttcagaagg gaacttgctg ggaggagtaa aaaatccgtt tcttgaggca
    21481 agtgaatggg gctggcagat cgatccagaa gggctgagaa tcgcattgaa tgaattatac
    21541 aatcgttacc agaaaccatt attcattgtt gaaaacggtc ttggagccat tgatcatatg
    21601 gaagaggatg gcacgattat tgatgattat cggatcgatt atttacgtcg tcatatcgaa
    21661 gcgatggcta atgcagtagc agacggtgta gatttgatgg gctatacgcc ttggggatgt
    21721 atcgatcttg tcagtgcatc aacaggagaa atgagtaaac gttacggctt tatctatgtg
    21781 gatctagacg atgaaggaaa tgggacactg aatcgatcaa agaaaaaatc ttttgattgg
    21841 tataaagaag taattgcctc aaatggcgta aacttgtaat taaagcagct gaatgaaaaa
    21901 gaacacactt ctcacatgtg atttgtgttc tttttttatt ttttatgtgc tattctttta
    21961 gtaatagtaa agcaaagggt gacgttatga aaaggacacg tgtactatac ttggaagtcg
    22021 cagataaaat taaagaagat attttctcag gaaaatatcc agtcggttcg atgttgccga
    22081 cagaaagtga attagaagaa ctgtttcaag tcagcaaaat cactgtccga aaggcaatcg
    22141 aactgctggc atcagatgaa tatgtcgcaa agaaaagtgg tcgtgggacg acggttctaa
    22201 gcaatcgtcc ttacaatcga ttatccaaag cggcaagctt tacgcaaatc ttggagaact
    22261 cccgatatga agtccggaaa gaaacgctgg atttgcaatt ggtccatata aagaaggaag
    22321 atcctttgtt ttcctttttc ggtgagcaag ctgtttgttt taagcgctta tattatttga
    22381 acaatcagcc ttatatttat tttgttcatt atcttccaca agaaatgatg caattcagca
    22441 gagaagaatt tggcaaagaa tctttgtatc gtttgctgac gaaaaaagga tatactattg
    22501 actcattttc tgatgatttc tcggcagtat ttttaacaga agaagaacaa ggaattctga
    22561 aaacagacgc acagatcggc atcaaacgga tacggaaatc gtctacgcaa attggggaaa
    22621 tgattgaata ttcggaggcg gtctaccata cggagctgca tccttaccat attgattatg
    22681 aaacataaat aaaaaaagag gttgtgaaaa agctgccctg catcaagtaa taagaacagc
    22741 caaacaaaaa tagcttctca tatttttcgt ttggttaggc ttattaccgc agatacacgg
    22801 ctgtttctgg attaccattt attctggata agggggtgtg gcacgatttt cagaaggaat
    22861 ctatgaacca atcactgtat tgattttagc ttcgatggta accccattcg gcttgacgat
    22921 cgcttatttc ttagggaaaa tcattcgtaa aaatatactc aatcgtcaag aaatcgatac
    22981 attgaagacc gcttttccta tggggatctg tcagatcaca gagggatgtt tccctatcgt
    23041 attgaacgac ttggcacgca atgtcatagc aacgggagtc ggtgggacag taggtggcgg
    23101 attaagcatg ttttggggcg cagatagccg tattccggca tcgggaatgt ttgcagtcgc
    23161 tacgatgacc agaccatggg cattcattgg tgcattgtta gctggttctt ttgtcacagg
    23221 aataaccatt ttattattga aaaaaccagt agatccgaat gcagaaatca tccaagaaga
    23281 aaaagaggaa gaagacatat cttgggatga tttgacaatt agttaggaga ggcagaatgg
    23341 attacaagaa aaaagtacaa tagatgtacc ttgagacagg aatggtatga aagaatcaga
    23401 gttagaaaga atcgaatata cagattttgg tttaggagcg atcgaaactg tccagagcat
    23461 cggcaccctc cttgaaatga cgatgaagga aaaatgagaa cctttcgttg tcgaaagggt
    23521 ctggtatacc ttatgtcgaa ggaaaggaaa caaaaaaact ttcctgtact attccaaaaa
    23581 ggaaagaaag ttattataca gtaaaaaaag aaattattct tcatgctaga gatcagtaca
    23641 cgttcgagcc caatatcaaa cactagttcc aggcaggcgc aacaggtgcg gttatcactg
    23701 aattttcttc cagcagtgac gattcaagtg atatttttac aaatccagct atttatcgtt
    23761 aacaaaaaga tttttaggag aagctgatga acaaaaatga tcaaattttg atcgtttagt
    23821 tcgtcggctt ttttatttag agaaacatca tttatcagtg aaacataaca cgagaacaaa
    23881 atgatttttt cgttaataaa agaaacaagt atttgttgtt taaaataata cacgttattg
    23941 gcatatagga cgaaatccca gtatcttcta taagtaagtc atttcatatc gatgaaaaca
    24001 cgttatttat ttttgtttta tctataaaat ggctgaaaaa tgattttttt ctaaatacta
    24061 tatatagtgg cgtctatcct atataccact aaaaaactac aaaatctagt cttttatttt
    24121 aaaaaaacac gtgtagaatg aagatagact tttgagttag ggagtgtttt tttatgaaac
    24181 ttactgtttt ttgcggttcc cgttttggta ataaagaaag ttacaaattt attgcgcaaa
    24241 cgttaggaaa atacatggca caagaagaaa tcgaactggt ttacggtggt tcatactccg
    24301 ggattatggg agtgattagt aaaacagtac tggaaaataa cggaaaagtc acaggtatct
    24361 atccgaatgg gctttttgaa actgaattgc ctggaaaaga tgttactaca tttattccta
    24421 cagaaacgat cgatgaaaga aaggtattat tatttgaaaa gggagatgct gtcctcgttt
    24481 tccctggagg tctaggtaca ttggaggaat tctcacaact tctttcttgg atagcaatcg
    24541 gtctgacgcc cgacaagcca atcggaatat tgaatattgg cggttattac agcggcttgc
    24601 aacaattatt agaaactttt gcaaaagagg attttatgga taaaaaatgg ttggatcaag
    24661 taatcttttc caacaatcca ttggaactgg tcaatgaatt acgagcagta tctattaaaa
    24721 atcagttatt attgaaggag gcaaaataat gagtcaaata tatttagcag gaccattttt
    24781 ttcagaggag caaatcgatc gagtaagtcg tatcgaaaaa gcgttggagg aaaacaaaac
    24841 agtcacaagt ttctactctc cacgtcatca ccaagaaagc aattatgaac tattcagcgc
    24901 tggatgggcg caggaagtat acgaaaaaga tatggaagaa ctgacaaatg cagaatttgt
    24961 tgttgctatc cttgactttg agcatcaaac aatcgatcca ggaacggctt acgaattagg
    25021 tgtggcaact atgttgaaaa aaccgatgat cattgtacaa gaagagacgg tacctacgaa
    25081 cttgatgatt acacaaagtc tccatacgta tttaaaatca gaccaagctg tacgtgaata
    25141 tgattttgaa acattgcctg ttgaaactta cgtaggcgag tacttataga agaggaaggg
    25201 ttgtatgtca gtgattttga tttcaggaac gattggtgca ggtaagagca gtttgacgga
    25261 tatgcttgca aaagagattg attctaaacc attttatgaa aatgtcgaag ataacgaagt
    25321 attgccgctc ttttattcaa atcctgagca gtacgctttt ttattgcaaa tcttcttttt
    25381 gaacaagcga tttttagcaa tgaaaaatgc tttagtgaac gatgacaatg tgctagaccg
    25441 atccatctat gaagatagcc tgttgttcca tctaaacgct gatttaggtc gggtaacgga
    25501 tatcgaagta cagcagtacg atagcttatt agatacgatg ctaaacgagt tagatgatgt
    25561 tgctccaaaa aaacggcctg atttgatggt ccatatcaaa gtttctttgg acacgatgct
    25621 agaacgtatc aaaaaacgtg ggcgtgacta tgaacagcta gaaagcgatg agacgttata
    25681 tacctattat gaaacgttga acacccgcta taatcaatgg tatgaagatt ttgatgtatg
    25741 tcctaaaata caagtggatg gggataaatt cgattttgta gaaaatccag aagatgcaaa
    25801 aaaggtgatc cgtcagatcc aagaaaaatt agctgaattg gaaggaaagc ctgctggaaa
    25861 atattttacg gataaccagc atgcaaaagg tcaagaatta ggctaaaaat aaaaaaccaa
    25921 acgacgggaa agaaa
//
LOCUS       DAFBVQ010000038        25808 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.038, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000038 DAFBVQ010000000
VERSION     DAFBVQ010000038.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25808)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25808)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25808
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.038"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            8..850
                     /locus_tag="LLC22_001736"
     CDS             8..850
                     /locus_tag="LLC22_001736"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter permease"
                     /protein_id="HBK5435017.1"
                     /translation="MLQNFINGLYDFHFLQNALITSVVIGIVSGTVGCFIILRGMSLM
                     GDAISHAVLPGVAISYILGINFFIGAIVFGLLASIIITFIKSNSVIKGDTAIGITFSS
                     FLALGVILIGVANSSTDLFHILFGNILAVQDIDKWITIGVSVLVLVTVVLFFKELLIT
                     SFDPLMAKAMGMNVSFYHYLLMILLTLVAVTAMQSVGTILIVAMLITPAATAYLYANS
                     LKTMIFISATVGACSSLLGLFIGYSFNIAAGSSIVLTAAFLFVISFLISPKQKFLRKK
                     ERKL"
     gene            850..1797
                     /locus_tag="LLC22_001737"
     CDS             850..1797
                     /locus_tag="LLC22_001737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011836396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal ABC transporter substrate-binding protein"
                     /protein_id="HBK5435018.1"
                     /translation="MRKWKAVLGSLGILIALFIFGACSTNSKDKDTVASNEKLKVVVT
                     NSILADITENIAKDKIDLHSIVPIGKDPHEYEPLPEDVQKTSKADLIFYNGVNLETGG
                     NAWFTKLVKNANKEENKDYFAASDGIDVIYLEGQSEKGKEDPHAWLNLENGIIYAKNI
                     EKQLAEKDPDNKKFYKENLDKYIEKLDSLDKEAKSKFASIPNDKKMIVTSEGCFKYFS
                     KAYNVPSAYIWEINTEEEGTPDQIKHLVEKLRTTKVPSLFVESSVDDRPMKTVSKDTN
                     IPIYSTIFTDSIAEKGQDGDSYYAMMKWNLDKIAEGLSK"
     gene            1812..2045
                     /locus_tag="LLC22_001738"
     CDS             1812..2045
                     /locus_tag="LLC22_001738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-dependent repressor"
                     /protein_id="HBK5435019.1"
                     /translation="MVQIKTTTILIYLLAIQELSKRKKKLKNNDLAKVLSVSPASVSE
                     MLAKLRYEDYLDIGFQLTDKGKKFIDDYKKGFK"
     gene            2376..2960
                     /locus_tag="LLC22_001739"
     CDS             2376..2960
                     /locus_tag="LLC22_001739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002364863.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5435020.1"
                     /translation="MESGLSHFEKEGFQQTKIRQLCLTAGVTTGAFYKHFTSKEALFE
                     EIIQPHINALINMYNEEFTKYLLNLENIDIEKSWRENFNELDPFINYIFENKRIFDLV
                     LFQSAGTKYQDIVEKITSFVTKKTVCCLDKLKTIGMINQNLVFNEEEIHFYIYSFYAT
                     FYDILKHSYSKEKTMLLTRRLYQFSVPGWIELLS"
     gene            3091..3758
                     /locus_tag="LLC22_001740"
                     /pseudo
     CDS             3091..3758
                     /locus_tag="LLC22_001740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360298.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor transporter transmembrane
                     protein EcfT"
     gene            3769..5184
                     /locus_tag="LLC22_001741"
     CDS             3769..5184
                     /locus_tag="LLC22_001741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297306.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="energy-coupling factor ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5435021.1"
                     /translation="MFEFNNVSFSYKDVKEQALVDLNFSIKKGSLTLITGSSGSGKST
                     LLKLMNGLIPRLYDGKLVGEILFENNSLQSLTQESISKNIGYVSQNPRGQFFTTNTTS
                     ELVFSMENFGFTKEHMDKRINELAELLDLSNILDKNIFSLSSGERQKISIGCSLSLNS
                     KLIILDEPSSNLDFKATKKLADLLCDLKNKGFTIVIAEHRFYYLKELIDQVLFVKNRT
                     VKTTTIQLLKTENNNALRKFDIFNSSIEVPYIEKVSADVLKVEEITYENILKDINFDV
                     KVGDVIGLVGKNGVGKTTLLRILMKIIRPTKGKIIENKKNLSSPFLVMQEMDYQFFTE
                     SVRSELALGNEIVSKDQQEKILKKMELYKMKDQLPFDLSGGEKQRLLVSIASLSKTNL
                     FLFDEPTSGLDYINMERIADLIKDLKEKGAVVIATHDPEFLYKTCNRIIYLKNGGIKK
                     DIKLRVEDSTLIEQIFNDITK"
     gene            5202..5771
                     /locus_tag="LLC22_001742"
     CDS             5202..5771
                     /locus_tag="LLC22_001742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MptD family putative ECF transporter S
                     component"
                     /protein_id="HBK5435022.1"
                     /translation="MKTKDYIFIGLATVISLVIYFFSIMVSSIGGAFGHSISPGIFGL
                     LSGIIFVYISYNYPRKGIFTIYTIVLLLFFTLMGGAYLPWFISSISMAILADIILSVF
                     GYDRAIPQVVSWVLMQLGSAAGQWIPIWFFTDRFRQDWIDRGQSAATMDAMIHYAVGI
                     WGIISVLVVASLSMIGVLIGRKVLKKYKK"
     gene            5881..7635
                     /locus_tag="LLC22_001743"
     CDS             5881..7635
                     /locus_tag="LLC22_001743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016398247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435023.1"
                     /translation="MKVYKKLFSYVPKMKYYGWLATLFSDFSVVLTVYGYYSIYKFLQ
                     SLIIVGDEYLAKSYAVQTVAWLTLGALFYIFSGLFSHILGFRLETNLRKKGISGLTEA
                     SFRFFDLNSSGYIRKTIDDNAAKTHMAIAHLIPDSAQAIVTPVLSVALGFFINFKIGL
                     VLIAMLVIGVFLLKKMTENTNFIQKYQESLDVLSSETVEYIRGIQVIKIFGAKVTSFK
                     ALNKAINDYAKFAYKYSLSGKTPFVLFQWLFFGIVCILIVPITFFITSLTTPKILAVD
                     LLMLFFLSGIIFVSFMRIMYVSMHLFEARYAVETLDSLYLEMKQDQLKYGNETQIKNC
                     DIAFENVSFSYKEECVLENFNLVLEQKRIYALVGKSGSGKSTIAKLISGFYNVDKGQI
                     KIGGKPLNHYSKDTIINTIAFVFQDTKLFNQSIYDNVSIANPQAPASKVFDALRLAGC
                     ESILEKFPEREHTLIGSKGVYLSGGEKQRIAIARAILKDAKIVIMDEASASIDPDNEY
                     ELQKAFQYLMKEKTVIMIAHRLSSIKSVDEILVLSEGKIVERGNHNELMAKHRVYKQL
                     VTNYENANDWRLDNEKFL"
     gene            7595..9361
                     /locus_tag="LLC22_001744"
     CDS             7595..9361
                     /locus_tag="LLC22_001744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435024.1"
                     /translation="MQMIGGLTMKNFYKKKFALTDQGAEALTKASISSFFVYCINMVP
                     AFIIMMLIDELVLENAKPRWLYFAVSFVTLLFMYWLLDREYENLYNSTYKESAHLRVQ
                     IADDLSNLPLSYFSKHNLSDLSQTIMSDVEGIEHAMSHAIPKAGGMALFFPFISVMLL
                     VGNVKMGLAVILPTLFSFVLILLSKKSQTKANTKYYDTLRENSEEFQETIELQQEINS
                     FNLSKKVQDRLFKKMEESERIHLKVELSTFSVMALSSIFSYVSLAVVILVGVHLLLTG
                     EVTILYVVGYLLAAIKIKDSFDSMKEAVLEIFYLAPKIQRIRAMKETSIQEGSDSPLK
                     SFDIELRDVSFSYDNNTPILDHISFTAKQGEVTALVGASGSGKTSILKLVSRLYDYDE
                     GCILIDGYDIKRVSPASLFSKIAIVFQEVTLFNTSILENIRIGNSQASDEEVKKAARL
                     ANCEDFIEKLPDGYHTLVGENGSSLSGGERQRLSIARAFLKNAPILILDEITASLDAE
                     NEKRIQESLNRLIQDKTVLIISHRLKSIEKVNKIVVMDQGKLVDQGTHNELYRRSEIY
                     KNLIKKTKLSEKFVYEKEAQSR"
     gene            9884..10153
                     /gene="rpsN"
                     /locus_tag="LLC22_001745"
     CDS             9884..10153
                     /gene="rpsN"
                     /locus_tag="LLC22_001745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002382898.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S14"
                     /protein_id="HBK5435025.1"
                     /translation="MAKKSKIAKAKKQMAMIEKYADKRQELKAAGDRTALAKLPRDSN
                     PNRLRLRDQTDGRPRGYMRKFGMSRIKFRELAHQGLIPGVKKASW"
     gene            10168..10347
                     /gene="rpmF"
                     /locus_tag="LLC22_001746"
     CDS             10168..10347
                     /gene="rpmF"
                     /locus_tag="LLC22_001746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_018345355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBK5435026.1"
                     /translation="MAVPARKTSKAKKRLRRTHQTVVKPEISFDEANGDYRRSHHVSL
                     KGYYNGKKVIKGASK"
     gene            10379..10756
                     /locus_tag="LLC22_001747"
     CDS             10379..10756
                     /locus_tag="LLC22_001747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435027.1"
                     /translation="MEIIYPPLVEEGLKYYLETTQQSLDKCTFYRSMVERGIITETGL
                     PTQQAIENGLVKDYYEDQGLSFDDFLRIYPIFEEYDEELFQCIDGYWEIPVDMKENLV
                     SQLESGELTFEDAQQIQAYLEDR"
     gene            10777..10926
                     /gene="rpmG"
                     /locus_tag="LLC22_001748"
     CDS             10777..10926
                     /gene="rpmG"
                     /locus_tag="LLC22_001748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L33"
                     /protein_id="HBK5435028.1"
                     /translation="MRQNIILECVETGERLYLTSKNKRNNPERLELKKYSPKLRRRAI
                     FKEVK"
     gene            10950..11933
                     /locus_tag="LLC22_001749"
     CDS             10950..11933
                     /locus_tag="LLC22_001749"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-binding protein"
                     /protein_id="HBK5435029.1"
                     /translation="MGIPVTIVSGFLGAGKTTLINQALQVSPYPREEIIIIENEFGEV
                     GIDHKLLVHSEERVLQLNNGCMCCSLRSDLLAILISLLETIEEHQQPISQIIIETTGI
                     ADPQPIIQTLLTAPQLRGRVYIDSLLTVIDSDSFELIEREPQALKQLVMADRIFVSRK
                     QNLNLSALKKLQREIKSINPLSDIRMFTHSETIQKKDFYNLKKFNHPLVFESDSSENH
                     YNGKYYHQHHQVHEFKSILLTSDQDIKKDFLLQWIDWLILTNQGSLYRFKGLIALQEQ
                     DFIVAMQEVNEQVNFQYTTRQKDQTTIILIGKMLDEERIKQSFDKLLAESK"
     gene            11963..12085
                     /locus_tag="LLC22_001750"
     CDS             11963..12085
                     /locus_tag="LLC22_001750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative metal homeostasis protein"
                     /protein_id="HBK5435030.1"
                     /translation="MEKTDISSAYRRLKSPNIKTRKRALKIIKEHKRNKMKKLA"
     gene            12103..13626
                     /locus_tag="LLC22_001751"
     CDS             12103..13626
                     /locus_tag="LLC22_001751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc ABC transporter substrate-binding protein
                     AdcA"
                     /protein_id="HBK5435031.1"
                     /translation="MKKISVGLIGIAALGLLGACSSTNDAKVSNDKDGKLEIVTTFYP
                     MYDFTKNIVGDEANVDLMVPAGSEPHDYEPSAKDMAKAHDADVFVYHNENMESWVPKA
                     KESWKKAGPNVVEGTKDMILLPGSEEEDHDHGEEDHHHELDPHTWVSPKMAIKEVSNI
                     KDQLVKLYPKKAKVFETNAEKYLTKLKRLDADYTTSLKEAKQKSFVTQHAAFGYLALD
                     YGLKQVPIAGLSPEEEPSSGRLAELKEYVKKNKINYIYFEKNANDKIAKTLANEAGIK
                     LEVLNPLESLTKEQMDNGEDYVSVMEDNLKALEKTTMVAGEEVVPEKEAKDEKTVANG
                     YFKDADVKDRELSDYTGEWQSVYPLLKDGILDEVFDYKAKINKDMTAAEYKDYYTTGY
                     KTDIDTINIKDNTIDFVVNGEHHQYTYKYVGYKILNYEKGNRGVRFNFETDDAGAGRF
                     KYIQFSDHGIAPSKAEHFHIFFGGESQEKLYNELHNWPTFYPASLSKHEIAQEMMAH"
     gene            13650..13889
                     /locus_tag="LLC22_001752"
     CDS             13650..13889
                     /locus_tag="LLC22_001752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304820.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435032.1"
                     /translation="MVRKVLLSMDSKNIDAYRRYRFAKQMRLNGSTLADIAATLHVSI
                     DTVHRVLKRDPDCCFIKVNTGRSRRLAKRHNSLAN"
     gene            complement(14082..14543)
                     /locus_tag="LLC22_001753"
     CDS             complement(14082..14543)
                     /locus_tag="LLC22_001753"
                     /inference="COORDINATES: protein motif:HMM:NF033563.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5435033.1"
                     /translation="MHHRGKTRHTKNHVESRGKICLTHSIHGRPKSADDRSDFGHWKA
                     DIVAGKTGGTCLVTLTDRKSCFLLAGKKVPRKKAAYVSEKMIELLSSIPNEAVKTITP
                     DRGKEFSNHFAVTEALNNMPFYFPDPHALGNNEQIKIRIDSFENTCQNRKR"
     gene            complement(14738..14956)
                     /locus_tag="LLC22_001754"
     CDS             complement(14738..14956)
                     /locus_tag="LLC22_001754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330794.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435034.1"
                     /translation="MSQYRHLTILERERIFLLHEEGFSISIIGNDIQHSPFTILHELR
                     RNKKKTIHLPKRKKIMLIEEKNADVITF"
     gene            15074..16690
                     /locus_tag="LLC22_001755"
     CDS             15074..16690
                     /locus_tag="LLC22_001755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002406986.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBK5435035.1"
                     /translation="MKKIPITILTGYLGSGKTILLNHILYGDHGKEIAVIVNDIGEVN
                     VDGVLVDKKGFKRTGEKLVSMPNGCICCTLREDLIVELDQLVQFSDLNQIVIEASGIS
                     KPIPIIQAIILAKNPLDIDLTQRLEIGAIIIVVDVKRFWDNFETGEKIQERKAEGNVV
                     EEEQDIRGLLIDQFECCNILLLNNSDLVSTKTIYKINGLIAKLQSNAKIIRTIKGEVD
                     LSKILNTNLFNIDETSYSVGWFKELELGYQNHIPETEEYGISSFIYRNRLLLDAQKFA
                     HLTDKNFPGNITRAKGFLWFAQHSDFSTIFETSGSYKSIESLNYWVASLPKIECQMII
                     QKNPELKEAWHPLFGERINKLVFIGMKMDQQCIKEQLEGCLTDSLNADNFRKISPFPW
                     KKSNMFSQISLMKFLRKAGVKIGDVIIIGILIITSFIPLFVFSIEKENETTEDAIKYA
                     IVRIDGKEMDRFDLDKINHKLVNYHPAKGQYNIVEIKDGRIRVKEDNSPDQIAVRTGW
                     ISKPGQTSICLPHKLVISIEKKESTDYYIY"
     gene            complement(16931..18271)
                     /locus_tag="LLC22_001756"
                     /pseudo
     CDS             complement(16931..18271)
                     /locus_tag="LLC22_001756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303667.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(18547..18702)
                     /locus_tag="LLC22_001757"
     CDS             complement(18547..18702)
                     /locus_tag="LLC22_001757"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBK5435036.1"
                     /translation="MPTVIHSDRGSQHRSFIYQELLNDHHITHSVSQTGTPVDNAVIE
                     AFHRSIK"
     gene            complement(18998..19330)
                     /locus_tag="LLC22_001758"
     CDS             complement(18998..19330)
                     /locus_tag="LLC22_001758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5435037.1"
                     /translation="MRKTYDRKFKLKISQDILEKKVTTKKIAEEYNISRPTISRWVSE
                     YRRYGKNAFAGQGKRLPDKADFYILEQENKRLKEEDECSTNTKIDTDLQGSLKNFTMK
                     ESKSINVL"
     gene            complement(19844..20035)
                     /locus_tag="LLC22_001759"
     CDS             complement(19844..20035)
                     /locus_tag="LLC22_001759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435038.1"
                     /translation="MNSLKEDFILAKAGNEEAVEAILKRFSSLIHKQSWRTGKYDQDC
                     YQECMLAIYLAISKFEIKE"
     gene            complement(20129..20515)
                     /locus_tag="LLC22_001760"
     CDS             complement(20129..20515)
                     /locus_tag="LLC22_001760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5435039.1"
                     /translation="MSDNDERVNAQLIRFFEKVILNTANTYYKKQEEIQKHEQLDQLP
                     PYLFTKDTIKFKQPINVLNVTLLVEDIKLAKILPLLKEPEQIFLIEKFIFDKTDKEIG
                     KVLGITRQGATNLKHRLYKKIQKMLV"
     gene            21209..22414
                     /locus_tag="LLC22_001761"
     CDS             21209..22414
                     /locus_tag="LLC22_001761"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YSIRK-targeted surface antigen transcriptional
                     regulator"
                     /protein_id="HBK5435040.1"
                     /translation="MFSDKEVLLKSLHVCLKLPIVVFNSEFSIIKEYRSDRTTYFFYD
                     YKKLLTDNIKKTKDFHFFTGDFNEMFLLYMFKTRYYLFGPFRANNIDKVFFKLKMNNL
                     NVAMADRERLYNSLQNLTLYSLGDIRDILILVHYFFTGKIEDLFHEPLIEYTENLSKT
                     IEQIKIDNLLSQNYDPEIYLFLYENKILEYVKNGDIRNLENMVFNLSNGIIPSVSGDT
                     IRSEKNYSIIVFEKLAQTSITLGMDIIEAYQSRDALIQENELAVSLPEVLKVRDSGIV
                     YYTKEIGKTKIEHLSPLISSVVQFIGLNIYKRITVKEIANYFSVSETKLRESFKNEMH
                     ITIYNYISKRKISTAKIMLKSNHTISEVSLGLGFSDSSHFSRVFKKYAGVSPKQYQLG
                     LVDNFNNIS"
     gene            22431..22865
                     /locus_tag="LLC22_001762"
     CDS             22431..22865
                     /locus_tag="LLC22_001762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360344.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435041.1"
                     /translation="MRLYHLRSLEELRKLDFNKKFFWEISDLSCFVESERLSNGNNSV
                     LNEYDKVVINKVKSLCEEARESISHINGSNFKQTLFNLIKLDAKISSYLFFLIHDEFM
                     DYQKLDQLIERESWEDYYVGLTFSEKLNNYKLIDYKYLSESN"
     gene            23482..>25808
                     /gene="esp"
                     /locus_tag="LLC22_001763"
     CDS             23482..>25808
                     /gene="esp"
                     /locus_tag="LLC22_001763"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="repetitive surface protein Esp"
                     /protein_id="HBK5435042.1"
                     /translation="MVSKNNKRVFLEKTKKRVLKYSIKKLSVGVASVLIGVGLVLGTT
                     ELVKAQDEISPSSPLETAISSVQVGDKVASGNTFQENPGYTKNYNFSDLQFSPQELTG
                     DTLKGNTIGFEVYGKHNIAASTKNWEIRLQLDERLAKYVEKIQVDPKKGIGSSRRTFV
                     RINDSLGRPTNIWKVNYIRASDGLFAGAETTDTQTAPNGVITFEKSLDEIFKEIGIDN
                     LKTDRLMYRIYLVSHQDDDKIVPGIDSTGYFLTDSDDFYNSLDVSENNPDQFKHGSVS
                     AKYEKPNTQTKDGSGSTGANGAIILDHKLTKNYNFSYSSSAKGTPWYANYKIDERLVP
                     YVAGIQMHMVQADKVTYDVSFESGTKVADLAIERREGHENYGIGSITNNDLTKLIDFA
                     NASPRPVVIRYVLQLTKPLDEILEDMKATAQVEENKPFGEDFIFDSWLSDTNKKLIQN
                     TYGTGYYYLQDIDGDGNPDDKEESGDTNPYIGKPELEEVYDVDTTVKGKVFIHELAGT
                     GHKAQLVDKEGTVLAEKTIAPNEKDGAPISDTVEFEFTGVDSSKLIAKDELKIQIVSP
                     GFDKPEEGSTVIKESPKAVDKQTVVVGFKPDAKESIRNNKNLPEDAEYSWKTEPDTSN
                     VTDSTKGIVTVKIGNRTFDVDVEFAVKASQAMENDATYVPITTTPETTVQSGKPTFDK
                     PDVPLAKDAFSISDVYNKDFGNASVDANTGIVTFTPAKGVGESEPITGTIPIKIVYQD
                     GSVGTTDLAVTVSKDIYENPGENIPAGYHKVTFTAG"
BASE COUNT         8895 a         3698 c         4831 g         8384 t
ORIGIN      
        1 gaataatatg cttcaaaatt ttattaatgg tctgtatgac tttcactttt tacagaatgc
       61 tctaattaca tctgtagtta tagggattgt ttctggaaca gtaggttgtt ttattatttt
      121 aagaggaatg tctcttatgg gtgatgctat ttctcatgct gttttgccag gagtagcaat
      181 ttcttatatt ttaggtatta atttttttat tggtgcgatt gtatttggtc tattagcttc
      241 tatcattatt acttttataa aaagcaatag tgtaataaaa ggagatacag caattggtat
      301 tactttcagt tcttttttag cattaggagt tatccttata ggagttgcaa atagctcaac
      361 ggatttattt catatcttat ttggaaatat tttagctgta caagatattg ataagtggat
      421 tacaattggc gtttctgttt tagtgttggt tacagttgtt ctatttttta aagaattatt
      481 aatcacttct tttgatccat taatggcaaa agcaatgggg atgaatgtca gtttttatca
      541 ttatctatta atgattctat taactttagt agcagtaaca gctatgcaaa gtgtgggaac
      601 tatattaatt gttgcaatgt taattacacc agctgctaca gcatatttat atgcaaacag
      661 cttaaaaact atgatattta tttcggcgac agtcggagcg tgctcatcat tgctaggttt
      721 gttcattggt tatagtttta acatagcagc aggatcaagt attgttttaa cagcggcatt
      781 cttatttgta attagttttc taatctcacc aaaacaaaaa tttttaagaa agaaggagag
      841 aaagttatga tgagaaaatg gaaagcagta ctgggaagtc tggggatttt gattgctctt
      901 tttatattcg gggcatgttc aacaaatagt aaagacaaag atacagtggc ttcgaacgaa
      961 aaattaaagg tagtagttac taattcgatt ttagcagata ttactgaaaa tatagcaaaa
     1021 gataaaattg atttacacag tatcgtacct attgggaaag atccccacga atatgaacct
     1081 ttgcctgaag atgttcaaaa aacttcaaaa gcagatttga ttttttataa cggtgttaac
     1141 ttggaaactg gaggaaatgc ttggtttaca aaattagtaa aaaatgcgaa caaagaggaa
     1201 aacaaagact attttgcagc aagtgatggc atagatgtta tttacttaga gggtcagagt
     1261 gagaaaggga aggaagatcc ccatgcttgg ttaaatttag aaaacggtat tatttacgct
     1321 aaaaatattg aaaaacagtt agcggaaaaa gatcctgata ataaaaaatt ctataaagaa
     1381 aatctagata agtatattga aaaattggat tctctagaca aagaagctaa atctaaattt
     1441 gcttcaattc cgaatgataa aaaaatgatt gttacaagtg aaggatgctt taaatatttc
     1501 tcgaaagcgt ataatgtgcc ttctgcttac atttgggaaa tcaacactga agaagaagga
     1561 acaccagatc aaataaaaca cttagttgaa aaattacgca caacaaaagt tccctcctta
     1621 ttcgtagaaa gcagtgtgga cgatagacca atgaaaacag tatcaaaaga taccaatatt
     1681 cctatctatt caacgatttt tactgattca attgcagaaa aaggacaaga tggtgatagt
     1741 tactatgcga tgatgaaatg gaacctggat aaaattgctg aaggcctttc gaaataattt
     1801 ggagggtagg tatggtacaa attaaaacga ctactatact aatttattta ctagcaattc
     1861 aggaattatc aaaaagaaaa aagaaattaa aaaataatga tttagcaaaa gttctaagtg
     1921 ttagtccagc atctgtaagt gagatgctgg ctaaacttag atatgaggac tatttagata
     1981 taggatttca attaactgat aaagggaaaa aatttattga cgattacaaa aaaggtttta
     2041 agtaaaagac tttattttta gggaggataa gaaaatggct attggagtga ttatgatagg
     2101 acttacccta atagctggat ataatttttt taaatctttc tcggattatt ttagaaaagg
     2161 tgaatgattt agatgagtct attaattctt gtaggattgc tttttgtatc agttattttg
     2221 ctctttctca ttagtttagc tctaaggaat gagttcagta atagacgtta acgattgaaa
     2281 cttcaagtcc tgtgtaagat aatatagtta attcatctta ttaggaggaa gtacccatag
     2341 aaaccagaga ttatattaca actcaccaaa aattaataga aagtggacta agccattttg
     2401 aaaaagaagg atttcagcaa actaagataa ggcaactgtg cttgaccgca ggcgtaacta
     2461 cgggtgcttt ttataaacat tttacttcta aggaagcgtt atttgaagaa attattcagc
     2521 cgcatattaa tgcgcttatt aatatgtata atgaagagtt taccaaatac ctcttaaact
     2581 tagaaaatat agatatagag aaaagttgga gagagaactt caatgaatta gatccattta
     2641 ttaattatat ttttgagaat aaacgtatat tcgatttggt tttattccaa tcagctggaa
     2701 ccaaatatca agatattgtt gaaaaaatta catcatttgt gacaaaaaag acagtctgtt
     2761 gtctagataa gttaaagact atcggaatga tcaatcaaaa tttagtcttt aatgaagaag
     2821 aaatccactt ctacatttac tcattctacg ctacattcta tgatatattg aagcatagct
     2881 attcaaaaga aaagactatg ctattaacca gaagattgta tcaattttct gttcctgggt
     2941 ggattgaatt actgagttaa ttaaaaaaaa gcttgcattg agaattgttc tcagttatgc
     3001 tttttgataa gatcgcactg ttatctgaat aacggtgcat ttttgtcagc ttaagataac
     3061 agtgcgatct tattttttgg aggtgaaaga gtgtcaaaaa tcaatccgtt aaccttgatt
     3121 actttaaata tttttttccg gtcattattt ttttaggaaa gggaaatata tttcaagtgg
     3181 ggtgtttcat tattgctaca gttttagtat tgatgtttcg taaaataaag acatgtattt
     3241 atttcatctt gatttattca gttctgtttt tagtaatgaa aattattgat gctatcaaga
     3301 tagagttttt tactatattt tttgggacat ccttatatat tgtatttcga atgttgccgg
     3361 tcgtaatgat ctcatggttg ttggttagtg tctatactag caatgaatta ttatcctctt
     3421 tagaaaaaat acatttaccg aaaaaaataa tgttaagtat tacagtagtg atcagattct
     3481 ttccgactta tcgttctgaa ataagaatga ttaaagaatc tttaaaaatg agaaacattc
     3541 gcttgtcttt ttttcagcct ctgcaatatt tggaatttct gttagttccc gttcttatac
     3601 gtgcaactat gattgctgaa gaaatgaccg ctaatgcaat aacaaagggg atagaatctc
     3661 ctgtgaaaag aagttcttac tataaaacaa acatgagctt attagactat atcatcctgt
     3721 tttccgttac tatttttttc ttaagtattt tgatttgagg tgaaagaatt gtttgaattt
     3781 aacaatgttt ctttttcata taaggatgtt aaggaacaag cgcttgttga ccttaatttt
     3841 tcaataaaaa aaggcagtct tacattgatt actggttctt ctgggagtgg gaaatccaca
     3901 ctattaaagt taatgaatgg acttattcca agactttatg acggaaaatt ggttggggaa
     3961 attttatttg aaaataactc gctacaatcc ttaacacaag aaagtatatc aaaaaatatt
     4021 ggctacgtaa gtcaaaatcc tagaggacaa ttctttacaa caaatacaac gagtgagtta
     4081 gtattttcga tggaaaactt tggatttaca aaagagcata tggataaaag aatcaatgaa
     4141 ttagctgaat tattagatct ttcaaatata ttagataaaa acattttttc gctatcaagt
     4201 ggtgaacggc agaaaatttc tattggatgt agtttatcgc taaactctaa attaattata
     4261 ttggatgaac cgtcttcaaa tttggacttc aaagcgacta agaaacttgc tgacttactt
     4321 tgtgatttaa aaaataaagg atttactatt gttatagctg aacatcgttt ttactatttg
     4381 aaagaattaa ttgatcaagt tctatttgtt aaaaatagaa ctgtaaaaac tacaactatt
     4441 cagttgttaa aaactgaaaa caataacgca ttaaggaaat ttgacatttt taatagttcg
     4501 attgaagttc cctatatcga aaaggtaagt gcagatgtat taaaagttga agaaattact
     4561 tatgaaaata ttctaaaaga cataaatttt gatgtcaaag ttggagatgt tattggtttg
     4621 gtagggaaaa acggtgtggg gaaaacaacc ttactaagaa tactcatgaa gattattcgc
     4681 cctaccaaag gaaagataat cgaaaataaa aaaaatttgt catcgccgtt tttagtaatg
     4741 caagaaatgg attaccaatt tttcacagaa tcagtgagga gcgagttagc cctggggaat
     4801 gaaatagtta gtaaagatca gcaagaaaaa attttaaaaa aaatggaact ttataaaatg
     4861 aaagatcaat taccgtttga tttatccggt ggagaaaaac aaagattatt ggtttctata
     4921 gcttcattgt caaaaactaa tttatttcta tttgatgaac ctacaagtgg gttggattat
     4981 atcaatatgg aaaggattgc tgaccttatt aaagacttaa aagaaaaggg tgcagtagtt
     5041 atagccactc atgatccgga atttctttat aaaacatgca atagaattat ttatttaaaa
     5101 aatggtggaa taaaaaaaga tataaaactt agagtagaag attcaacttt gatagaacag
     5161 atttttaatg acataacgaa atagaattga ggagaatata tatgaaaaca aaagattata
     5221 tttttattgg tttagctaca gttatttccc tagtaattta ctttttttca ataatggtta
     5281 gtagtattgg tggggcgttt ggtcacagca tatccccagg gatttttgga ttattatctg
     5341 gaatcatatt tgtttatatt agctataact accctagaaa aggaattttt actatttaca
     5401 caattgtttt attgttattt tttacgttaa tgggcggggc gtacttacct tggtttatca
     5461 gttcgattag tatggcgatc ttagctgata ttattctatc tgtatttgga tatgatcgag
     5521 caattcctca agttgtgtct tgggttctaa tgcaactagg cagtgctgcc ggacagtgga
     5581 ttcccatatg gttctttaca gatcgttttc gtcaagactg gatagataga ggacaatctg
     5641 ctgcaacaat ggatgcaatg atccactacg cggtgggtat atggggaatt atttcagtgt
     5701 tagttgtagc aagtttatct atgattggtg tattgattgg aagaaaagtc ttaaaaaaat
     5761 acaaaaaata gaacgtagtt taccttctat ctgtttgtac atctctaatt tacgctatta
     5821 cggaaagcat taacagttgt aaacgaataa gagaagaaat tgaatgcggg ggaggaaaaa
     5881 atgaaagtat acaaaaaatt atttagttat gtccctaaaa tgaaatacta cggatggtta
     5941 gccactttat tttctgattt ttctgtcgta ttaacagtct atggatatta cagtatttac
     6001 aaatttcttc agtctctaat tattgtagga gatgaatatt tagctaagag ttatgcggtt
     6061 caaactgttg cttggttaac tttaggagct ttattttata ttttttctgg cttattttct
     6121 catatccttg ggtttcgctt agagactaat ttgagaaaaa agggaattag cggtttaaca
     6181 gaagcaagtt ttcgtttttt tgatttaaat tcttcgggat atattcgaaa gacaattgat
     6241 gacaacgcgg ctaaaacaca tatggcaatt gctcacttga ttccagatag tgctcaagcc
     6301 atagtaacac ctgttttatc agttgcctta ggctttttca ttaactttaa aattggattg
     6361 gttctaatcg ccatgttagt aattggtgta ttcttgttaa agaaaatgac agagaataca
     6421 aattttattc aaaaatatca agaatcgtta gatgtgttaa gctctgaaac ggtagaatat
     6481 atccgcggaa ttcaagttat aaagatattt ggtgctaaag taacatcatt taaagccttg
     6541 aataaagcaa ttaacgatta tgctaagttt gcatataagt attctttgag tgggaaaaca
     6601 ccttttgttc tttttcaatg gctatttttt ggcatagttt gcattttgat agttcctata
     6661 acctttttta taacttctct taccactccc aagatcttag ctgttgactt gttgatgttg
     6721 ttttttttaa gtggaattat ttttgtttct ttcatgagaa taatgtatgt aagtatgcac
     6781 ttgtttgaag caagatatgc agtcgaaaca ctagactccc tttatttaga aatgaagcaa
     6841 gaccaactaa aatatgggaa cgagacacag attaaaaatt gtgacattgc atttgaaaat
     6901 gtcagctttt catacaaaga agagtgtgtt ttagaaaatt tcaacttagt tttagaacaa
     6961 aaaagaattt atgcattagt aggaaaatca ggaagcggaa agagtacgat agctaaacta
     7021 atttcaggtt tctacaatgt ggataaggga cagattaaaa ttggtggtaa gcctttaaat
     7081 cactattcaa aagacacaat tattaacaca attgcttttg tctttcaaga tacgaaacta
     7141 ttcaatcaga gtatttacga taacgtttct atagcaaatc ctcaagcgcc agcaagtaaa
     7201 gtatttgacg cgctaagatt agccggttgc gaatcgattt tagaaaaatt tcccgaaaga
     7261 gagcatacct taattggtag taaaggagtt tatctgtcag gaggagaaaa acaacgtata
     7321 gctattgcca gagcaatttt aaaagatgca aagattgtta ttatggatga agccagtgca
     7381 tctattgatc cagataatga gtatgaacta caaaaggctt ttcaatattt gatgaaagaa
     7441 aaaacagtta ttatgatagc tcatcgatta tccagcatta aatctgtaga tgaaattctt
     7501 gtcttgtcag aaggaaaaat agtagaacgt ggaaatcata atgaattaat ggctaaacat
     7561 cgagtgtata aacaattggt cactaattat gagaatgcaa atgattggag gcttgacaat
     7621 gaaaaatttt tataaaaaaa aatttgcttt aactgatcag ggcgcagaag ctttaactaa
     7681 agcttctatt tctagttttt ttgtatactg cattaatatg gtaccagcat tcattataat
     7741 gatgctgata gacgaattag ttttagaaaa tgcaaagccc cgttggcttt attttgcagt
     7801 atcgtttgtt actttgcttt tcatgtattg gttgttagat agggagtatg aaaacttata
     7861 taatagtact tataaagaaa gtgcgcattt aagagtgcaa attgcagacg atttgtcaaa
     7921 tttaccatta tcctattttt caaaacataa tttatcagat ttatctcaaa ctatcatgtc
     7981 tgacgttgaa ggtattgagc atgcgatgag tcatgcaata cctaaagccg gcggtatggc
     8041 tctgtttttc ccttttattt cagtgatgct tttggttggt aatgtcaaaa tgggattagc
     8101 tgttattttg ccaacgttat ttagttttgt cttaatcttg ttatcaaaga aatcccaaac
     8161 gaaagccaat actaaatatt acgatacttt gagagaaaac tcggaagaat ttcaagaaac
     8221 tattgaattg cagcaagaga ttaatagctt taatctatct aaaaaagttc aagacagact
     8281 tttcaaaaaa atggaagaga gtgaaaggat tcatttaaag gtagaattaa gtactttttc
     8341 agtcatggcc ttatcctcta ttttctcata tgttagttta gcagtagtca ttctagtagg
     8401 tgttcactta ctgttaacgg gtgaagtgac tatactctac gtcgttggtt acttactagc
     8461 cgcaataaaa ataaaggatt ccttcgattc tatgaaagaa gcagtgcttg aaatatttta
     8521 tttagctcct aaaatacagc gaattagagc tatgaaggaa accagtatcc aagagggatc
     8581 agatagtcct ctgaaatctt ttgacattga gttgcgagat gtctctttct catatgataa
     8641 caatacccca attttagatc atatctcttt tacggctaaa caaggagaag tgactgcgtt
     8701 agtaggtgct agtggttccg ggaaaactag tatcttgaaa ttagtgtcta gactgtatga
     8761 ttatgatgaa ggctgtattt taattgatgg gtatgatatt aaacgtgtat ctccagcttc
     8821 tttgtttagc aaaatcgcta ttgtttttca agaggtaact ttgtttaata caagtatttt
     8881 ggaaaatata cgtattggaa atagtcaagc gtcagatgag gaagtgaaaa aagcagctcg
     8941 tttagctaac tgcgaagact ttattgaaaa actacctgac ggttatcata cattggtcgg
     9001 agaaaacgga agttcacttt ctggaggaga gcgacaacgc ctatccatag cacgggcttt
     9061 tttgaaaaat gcgccaattt taattttaga tgaaattact gccagtttag atgcggaaaa
     9121 tgaaaaacgt attcaggaaa gtttaaatcg tttaatacaa gataagacag tactaattat
     9181 atcgcatcgc ttgaagtcta ttgaaaaggt aaataaaatt gtagtgatgg atcaaggaaa
     9241 actagttgat caaggtactc ataatgagtt gtatcgaagg tcagaaatat acaaaaatct
     9301 cataaagaaa actaaactat ctgagaaatt cgtctatgaa aaagaagctc aatcacgatg
     9361 atgaaatagg ctttaaatta acctacaatt tttgggatat agttataatt ctttttcaaa
     9421 aagaataatt ttattaaaca gcatctaatt ttgaatacac gaaagaatca gtatgattga
     9481 attagttcac ttaatgtcta ttcttataat ataaggaata atcaaagttt taaaaaattg
     9541 gcgataaacc agttaaacat aaaagattga ataaaaagtt atagtttctt tcatattgcc
     9601 gttttaagta gaggaaaagc tacttaaaac ggtatttgtg tttgattgga ctaataaaag
     9661 tgaattctta tttttcagag cctaaactgc atattctttt aaatgatttg attatctcta
     9721 tgtaccgata aattcgtttt caaatagtta tctattcata tgagttttat ttcatgttat
     9781 ttattgttga caagagcaac tcttgttggt aaagtatcag tgtcaaaacg taacgattac
     9841 gatttgaggt gtctaaatca aaataaaagg agtataaagg tatatggcaa aaaagtcgaa
     9901 aattgctaaa gcaaagaaac aaatggcgat gattgaaaag tatgcagata aacgtcagga
     9961 attaaaagcc gcaggagatc gcaccgctct cgctaaattg ccaagagatt caaatccgaa
    10021 tcgtctgagg cttcgtgatc agacggatgg tcgtccaaga gggtatatgc gaaagttcgg
    10081 tatgtcccgt attaagttta gagaacttgc ccatcaaggg ttgattcctg gagtaaaaaa
    10141 agcaagttgg taaaaggagg aaatatcatg gcagtaccag caagaaaaac atctaaggcg
    10201 aagaaacggt taagaagaac tcatcaaact gtagtaaaac cagaaatttc atttgacgaa
    10261 gcgaatggtg attatagacg tagccatcat gtatctttaa aagggtacta taatggaaag
    10321 aaagtaatta aaggagcttc aaaatagttt aatatataac ttttaggagg gaatcaaaat
    10381 ggaaattatt tacccacctt tagttgaaga aggattaaag tattatcttg aaacgaccca
    10441 gcaatcgcta gataaatgca ctttttatcg ttcgatggta gagagaggaa ttattactga
    10501 aacgggttta ccgacccaac aggcaattga aaatggatta gtcaaagatt actatgagga
    10561 ccaaggctta tcatttgatg attttttaag aatctatcca atttttgaag agtatgacga
    10621 ggagttattt caatgtatcg atggttattg ggagatacct gttgatatga aagaaaattt
    10681 agtttcacaa ttggaatctg gcgagttaac ttttgaagat gcacaacaaa ttcaagcata
    10741 tcttgaagat cgataagtat tgaaggagga agatttatgc gtcaaaatat tattttggaa
    10801 tgtgtcgaaa ctggagaacg tctgtatctc accagcaaaa ataaacggaa taaccctgaa
    10861 cggttagaat taaaaaagta ttcgccaaaa ttgcgcagac gggcaatttt taaagaagtg
    10921 aaatagctaa gtggtaaaaa ggtgacaaaa tgggcatacc agttacaatc gtttctgggt
    10981 ttttaggggc tggaaaaaca acgctaatca atcaagcctt gcaagtctca ccctacccca
    11041 gggaagaaat tattataatt gaaaatgagt ttggtgaagt tgggattgat cacaaattat
    11101 tagttcatag cgaggaacgg gtgttacaac taaataatgg atgtatgtgt tgcagtcttc
    11161 gcagtgattt attagcaata ttgatttctt tactggaaac aatagaagaa catcaacaac
    11221 caatttcaca aatcatcatt gaaactacag gtatagcaga tccccaacca atcattcaaa
    11281 cacttttaac agcgcctcaa ctaagaggaa gagtatatat cgatagttta ttgactgtta
    11341 ttgatagtga cagttttgaa cttattgaaa gagaaccaca agcccttaag caacttgtca
    11401 tggcagatcg catttttgtg tctagaaaac aaaacttgaa tttatctgca ctaaaaaaat
    11461 tacagagaga aatcaaaagt attaaccctt tatccgatat tcgaatgttc acacatagtg
    11521 aaacgattca aaaaaaggat ttttataatt tgaaaaaatt taatcatccc ttagtttttg
    11581 aaagtgattc atcagaaaat cactataatg gcaaatacta tcatcaacac catcaagtac
    11641 atgagtttaa atcaattctc ttaacttcag atcaagacat aaaaaaagat tttttactcc
    11701 aatggattga ctggctgatt ttaaccaacc aagggagcct gtatcgtttt aaaggattga
    11761 ttgctttaca agagcaggat tttatagttg ccatgcaaga ggtaaacgaa caggttaatt
    11821 ttcaatacac cactcgacaa aaagaccaaa ccactattat tctaatcgga aaaatgttgg
    11881 atgaagaaag gatcaaacag agttttgata aattactggc ggaaagcaaa taatgataag
    11941 tagtgattgg gggtaatttc taatggagaa aacggatata tctagtgcat atcgacgact
    12001 taaaagcccg aatattaaaa ctagaaaaag ggcattaaaa attatcaaag aacataaacg
    12061 aaataaaatg aagaaattag cataattaag gaaggaaaaa gaatgaagaa aatcagtgta
    12121 ggacttattg ggatagcagc tctaggatta ttgggagctt gctccagcac taatgatgca
    12181 aaagtatcga atgataaaga tggaaaatta gaaattgtaa caacattcta tccaatgtat
    12241 gatttcacca aaaacatcgt cggcgatgaa gcgaacgtgg atttaatggt tccagcggga
    12301 tcagaacctc atgactatga gccctcagct aaggatatgg caaaagctca tgatgctgat
    12361 gtttttgtat atcataacga aaacatggaa tcatgggtac caaaagctaa agaaagttgg
    12421 aagaaagctg ggcctaatgt agtagaagga acaaaagaca tgattttatt gccaggtagt
    12481 gaagaagaag atcatgatca cggagaagaa gatcaccatc atgaactaga tcctcatacg
    12541 tgggtttcac ccaaaatggc aattaaggaa gtttcaaata tcaaggatca gttagttaaa
    12601 ttgtatccga aaaaagcaaa agtatttgag acaaatgctg aaaagtattt gactaaactg
    12661 aaacggttgg atgctgacta taccactagt cttaaagaag cgaaacaaaa aagttttgtg
    12721 acgcaacacg cagcctttgg atatttagct ttggattatg gattgaaaca agttcctatt
    12781 gctggactaa gtcctgaaga agagccatct tctggtcgat tagctgaatt aaaagagtat
    12841 gttaaaaaaa ataagatcaa ttatatttac tttgaaaaga atgctaatga taaaattgca
    12901 aaaactttgg ccaacgaagc tgggataaaa ttggaagtac tgaatcctct tgaaagtctt
    12961 acaaaagaac aaatggataa tggtgaagat tatgtttcag taatggaaga caatctaaaa
    13021 gcgttagaaa aaacaactat ggttgctggt gaagaggtag ttccagaaaa agaagcgaag
    13081 gatgaaaaga cagttgctaa tgggtacttt aaagatgccg atgtgaagga tcgcgaattg
    13141 agtgattata caggcgaatg gcaatctgtt tatccgttgt taaaagatgg aattttggat
    13201 gaagttttcg attacaaagc aaaaatcaat aaagacatga cagctgccga gtacaaagat
    13261 tattatacta ctggctataa gacagatatt gatactatca acattaaaga caacaccatt
    13321 gattttgtag tcaacggtga acatcatcaa tacacataca aatatgttgg atacaaaatt
    13381 ttgaattatg aaaaaggaaa ccgtggtgtt cgttttaatt ttgaaactga tgatgcaggt
    13441 gctggtcgtt ttaaatatat tcaatttagt gatcatggaa ttgcaccaag taaggcagag
    13501 catttccata ttttctttgg tggagaaagt caagaaaaac tctataatga attgcataat
    13561 tggcctactt tctatccagc ttcattgtct aaacatgaaa ttgctcaaga aatgatggct
    13621 cattaaaatt caatttttgg aggaaataca tggtaagaaa agtattattg tctatggatt
    13681 ccaagaatat tgatgcttat cggcgttatc gatttgcaaa gcaaatgaga ttaaatggga
    13741 gtacattagc tgatattgct gcaactttac atgttagtat tgacacagtt catagagtat
    13801 taaaacggga tcctgattgt tgttttatca aggtcaatac tggaagaagt agacgtttag
    13861 caaaacggca taatagcttg gccaattaat tgataatacc agagtagatc atttttccct
    13921 tatttggatt tgatctgctt tttattatgt cttgaattgt caaatcaagc gcaacacttt
    13981 atcaaagaag acttcataag gtgttctcca atctaaacac tttctaggtc tgttattcag
    14041 tttttcaatc atctgattta tcgttgagtt atctaccgta gctatctctt tcgattttgg
    14101 caagtattct cgaatgagtc tattcgtatt ttaatttgtt cattgttgcc aagggcatga
    14161 ggatctggaa aataaaaggg catattattc aatgcttctg taactgcgaa atgattggag
    14221 aattcttttc ctctatctgg agtgatcgtt ttgaccgcct catttggaat actgcttaaa
    14281 agttcaatca ttttctcgct cacataagcg gctttctttc tggggacctt ctttcctgct
    14341 aaaaggaagc atgattttct gtctgtcaaa gtcactaaac aagtaccacc agttttgcca
    14401 gctacaatat cggctttcca atgaccaaaa tcacttctat catctgcgga ttttggacgg
    14461 ccatggatcg aatgagtaag gcaaatcttt ccacgagact cgacatgatt ttttgtatgt
    14521 cttgtttttc ctcgatggtg caatgaacgg atcaggcctt tattgccgtg tgagaggggt
    14581 tctgtatcga aaagatcatt gcaaattgca cgttagatcg tgataaaact aattgaaaag
    14641 tccatatgtt catgcttcaa acgattcgag atttcctctg gcgaccactg aaaatcgaca
    14701 aataaatgac gaacaattga ccaaactcac ggatcattta gaatgtgata acgtccgcat
    14761 ttttttcttc gataagcata atttttttcc gctttggaag gtgaatagtt tttttcttgt
    14821 ttcttctcag ttcatgtaaa atagtaaacg ggctatgctg aatgtcgttg ccaattatac
    14881 taatagaaaa tccttcttcg tgaagcagaa agattctttc tcgttcgagt atagtaagat
    14941 gacgatactg gctcataatt attttccttc taggagtgtt ctcgacaaac ttatactagt
    15001 tggatatcga ttatgactca tttttatgtg ttgcacttaa agtgtaaatt caaggtatag
    15061 aaagaggttc cctatgaaaa aaatacctat tacaatctta actggctatc ttggttcagg
    15121 aaaaacgata cttctaaatc atattctgta cggtgatcac ggaaaggaaa ttgctgtcat
    15181 tgtaaatgac ataggggaag taaatgttga tggggtatta gtcgacaaga aaggttttaa
    15241 aagaactgga gaaaaacttg tttcgatgcc gaatggatgc atttgttgta cattacgcga
    15301 agatttgatt gttgaactag atcaattagt gcaattttct gacttgaatc aaattgttat
    15361 tgaagcttca ggaatcagca aaccaattcc aattattcaa gcaattatat tagctaaaaa
    15421 ccctttagac attgatttga cccaacgatt agagattggt gccattatta tagtagtgga
    15481 tgtaaaacgt ttttgggata atttcgaaac gggtgaaaag attcaggaaa gaaaagctga
    15541 aggtaatgta gttgaagaag aacaggatat tcgtggcttg ttaattgatc aattcgagtg
    15601 ttgtaacata ttacttttaa ataatagtga cttagtgtca accaagacga tttacaaaat
    15661 taacggtcta attgctaagt tacagtccaa tgccaaaata attaggacaa ttaaaggtga
    15721 agtagactta tcgaaaattc taaatacaaa tctttttaat atagatgaga cttcctattc
    15781 agtgggctgg ttcaaagagt tagagcttgg ctatcaaaat catattcctg aaacagaaga
    15841 atatggtatc tcaagtttta tctatcgaaa tcggttactc cttgacgcac aaaaatttgc
    15901 ccatcttacg gataaaaatt ttcctggcaa tattacaaga gcaaaagggt ttctttggtt
    15961 tgcccaacat agtgattttt cgacgatctt tgaaacatcg ggtagctata aaagtattga
    16021 atcattaaat tattgggtag ctagtttacc taaaattgag tgtcaaatga ttatacaaaa
    16081 aaatcccgaa ttgaaggaag cctggcatcc gttgtttggt gaacgcatta ataaactagt
    16141 ttttattggt atgaagatgg atcaacaatg tattaaggaa caacttgagg gttgtttaac
    16201 tgattctctt aatgcagata atttccgaaa aatttcacca tttccatgga aaaagtctaa
    16261 tatgtttagc cagatatcgt taatgaaatt tttaagaaaa gctggtgtca agataggcga
    16321 tgtcataatt attggcattt tgattattac ctcttttatt cccttatttg tattctctat
    16381 agaaaaggag aatgaaacaa ctgaagatgc tatcaaatat gccatcgttc gaattgatgg
    16441 caaggaaatg gatcgcttcg atttggataa gatcaatcat aaactcgtga attatcatcc
    16501 tgcgaaggga caatataata ttgttgagat taaagatgga agaattcgag ttaaagaaga
    16561 taatagtcct gatcaaatcg cggttagaac tggatggatc tcaaaacccg gtcaaacgag
    16621 tatttgttta ccccataagt tagttattag tattgagaaa aaagaaagca cagattacta
    16681 catttactaa tctggaaata gatgaggagg tttttaataa gaaaaagata ttattattaa
    16741 taatagcagg ggctttatta agtgtgttaa gcgcttgtgg acaagaaaaa gaagcggtga
    16801 caacaggcac aagtatcttt aacgggacct gcaatggttt agttaacagt cggttagatt
    16861 acttattttg gctcttcgtc aatgagtgtt ggtgaagaaa ttcaatagaa taatcgagat
    16921 actcacacgg ctagacagct atcttgtcta gccgtgttgt tgttctggct ttagtcagtt
    16981 gggtagtatt cttagttttc ttaaaatatt ttcctcgata taaaaagatt cgttctcggt
    17041 agttttgaaa gtttctatag ccataggcaa ttcgttttag tactttgata tggttattca
    17101 aacattctat agggccgttg gaatagggaa cgcgcaacgc tcgtttgatt tctgtttggt
    17161 atttcttgaa ggtcgtgaac actggttggt agtgctctgg caactccttg tagtcttctt
    17221 ttaggagcgc gacgaattca ggaacatctt gtcttctgat aacggaaaga aaatcctggt
    17281 agacttcgta gcctcgcttt aaggaatcat cataagataa tagccgatcg actatctctg
    17341 cttctgtcag atgatctcga aatgacggac gccagtagcg atgctgacct ttcaattccc
    17401 acgcattctt ttgaagtagt ttccagtatt tctttaagtg cttcgaccga cgatcccctt
    17461 ttttaaaggt cttcattact tgaattcggt ggttggtaaa agcccgacca atgtgttggc
    17521 taatatgaaa gcgatcggcg acgattcggg cattcggaaa acactctttc accaatgtgc
    17581 gatagggtgt atagaaatct gaaaccacta gacgcacttg ttcacggact tttatagggt
    17641 agcgcaagaa atagtcgcgt aaaggattga gttgccgatt ttccacaata tcaatcagtt
    17701 gatgggtctt gccgtccatc atgacaaagc tcatggctcc cgagacattt ttcactgatt
    17761 tgaattcatc gaaacacacc acttctggta acagctggct caaagaaatg gttttaggcc
    17821 gaaggctgcg aagtattcga atgacagtgg tcggagaaat gtgcttcata cgtgcgatca
    17881 aagacataga aagaggttcg cttaatagct caagaatggc ttgtttgact ctgcgagcaa
    17941 tggagcagcg acgatcacta actgaatctt ctgctaaaaa agtctttcca cagtgtttac
    18001 atttgaagcg ctgtttgtta atccgcagaa tggtcttgta gttactgaca tcattcaata
    18061 agatggatac ttttttccag ccctatttaa tgatcgtttg ttcattttga tagtggcgat
    18121 gaaagcattc ctccggttga taggtcaatg tgccatcaaa agcaaaacat gtttcgtcat
    18181 tgatgcgctc tttgcgaaag gcatcctcat gaaaggtaag atttaggtct agaatatcta
    18241 gtaactcttt ggtaaactct gaataggaca tcttgaaaca ctactttgaa tggtttttgt
    18301 cgactttatt ctaaaggatt ttaaggtgtc tgtttgcgtt tattagaaaa aagaaaaagt
    18361 attggcaaca gaaggcgtca ccaacactag atattataga tcccttattt tcttcgcttc
    18421 aaattgtcaa ggagtcatca taaattttgt atggattctt ttgtttgggt agtagtcttc
    18481 taaataatct tggattaaca ccttcatctc tattttactt ttatatttgt tggagtcgat
    18541 taattctcat ttgattgatc gatgaaacgc ttcaattact gcattgtcaa caggagtccc
    18601 agtttggctc actgaatgtg tgatgtggtg gtcgttcaac agctcttgat aaataaaaga
    18661 ccgatgctgg ctacctctat cggaatgaat taccgtaggc aattctcctt aataaatttg
    18721 taatggacgg acgacaatct ctttttttat gtgtgaatct accatatagt aacgtagaat
    18781 acgagttgct aagtcaatat aggtggacaa atagaggcga ccgtcattac atggaatgta
    18841 agtaatatcc atcacccaaa cagcatcaat ttggttctgt tcaaattatc gattcaacat
    18901 ttttttacca tttctttgat tgttttttct ctaccatgag aagatttgcg tcgatgaaat
    18961 cctcttgtgc ataaattcat ttcacgcata agaacagcta caacacgttt attgatttcg
    19021 attccttcat cgtaaagttt ttgagtgatc cctggagatc cgtatcgatc tttgtgttcg
    19081 tagaacactc gtcttcctct tttagtcgtt tattttcctg ttcaagaatg tagaaatctg
    19141 ctttatcagg taatcttttt ccttgtccag caaaagcatt tttcccgtat cgacgatatt
    19201 ctgaaaccca tcgggaaatt gttggacgag agatattgta ttcttcagca attttcttgg
    19261 tagttacttt tttctcaagg atatcctgtg aaatctttag tttaaattta cgatcatatg
    19321 tttttctcaa tagagttcat tccttccggt aacgtaactg atagtcaaga aaagtgtatc
    19381 atagcccaac ttagtatcag ggtttgtcaa ctaaactgtg gaagttgata gataagagtt
    19441 tttaacaacc aaaattctct tgactatttt tgaaatcaga caaattttga ttggacacat
    19501 agttgaataa atctaccgtc gttacggaag gtaaatcgca tgcttttcaa ttctagagga
    19561 gaagtcctcg ttgaagtacc atagcccagt tctggattcg acctcctgcc cacttcatac
    19621 gtaaataaag taattttagg agtgagactg tgacaaaagt tatttttaag ctaaaaacga
    19681 attaaaaaac gttgataatt aaaatcattc gttttagatt ctatgaatca ttatagaacg
    19741 ctgtaaaatc gatactttat aattataaag aagatagttt caaatttatt gttcgaaatt
    19801 tgaaactatc tttttactta tgtcacagac tcccttagtt gagttattct ttaatttcga
    19861 atttcgagat agctagatat attgcaagca tacattcttg ataacaatct tgatcatatt
    19921 ttccagttct ccaggattgc ttatgaatca aagagctaaa tcttttgaga attgcctcaa
    19981 cagcttcttc atttccagcc tttgctaaaa tgaaatcttc ttttaaagaa ttcataaatc
    20041 taccttcttc ccatggactt ataatctatt tctttgggaa ggaggagaac gagcaaagaa
    20101 gcatacaaaa ttagttatta tgcagatatt aaaccagcat tttttgaatt tttttgtaaa
    20161 gtcgatgttt taaatttgtc gcaccctgtc ttgtaatccc cagaaccttt ccaatttctt
    20221 tatcagtttt atcaaagata aatttttcga taagaaaaat ttgttcaggt tctttcaaca
    20281 aaggaaggat ttttgctaat tttatatctt caacaaggag agtcacattt aaaacattaa
    20341 tcggttgttt aaattttata gtatctttag taaacaaata tggtgggagt tgatcaagtt
    20401 gttcatgttt ttgaatttct tcttgttttt tataataagt attagcggtg ttcaaaatga
    20461 ccttttcaaa gaatcgaatc aactgggcat ttacgcgttc gtcgttatct gacatattgc
    20521 acacctcctc cattaagatt taaagggaaa agaggcaaaa aacacgaaaa gaagctaatg
    20581 caattatgct gcgctgcgaa taacttctat aagctcacat gcattgatag gactgctgat
    20641 gtttattttc aaaaatgttt ttttagttga taatggatag ttatctttat acttagaaaa
    20701 gaaaattcat atatcttctt aaatatcaaa catgtcctta tggctaagaa aatgtcttga
    20761 gctttttacg tataataaat cttttctaaa acctcctttt ggataatatt cttattcgtg
    20821 tatagattgt attttttatt tcttccccct tcataattaa caactagaaa agagttcgaa
    20881 tagacacgta tttgaacgaa aatttttatt ggattcccaa attggaatat ttagaaacga
    20941 aaaattccta ttatctgtat agtgcttaga taataacgga tcataataat tattgtcttt
    21001 gaactagata tatgtaaata gtattcatca tgatgaaaaa tgatgagttc tcggtgataa
    21061 aatgtacttt ttacggtgga atatacatga aagcgataag tggatatttt ataatgaagt
    21121 aagttagctt attttgacag aggaatagta ttttagataa cgtataaaat actatttaat
    21181 gatgtagaaa ggaaagagag aaacaaaagt gttttcagat aaagaagtct tattaaagtc
    21241 tcttcatgtt tgtttaaagt tacctatcgt ggtttttaat tccgaattca gtattataaa
    21301 agagtatcgc tcagatagaa ctacttattt tttttatgat tataaaaagt tactaactga
    21361 taatattaaa aaaactaaag atttccattt ctttactggt gattttaatg agatgtttct
    21421 tctatacatg tttaaaacca gatattactt atttggtcca tttagagcaa ataatattga
    21481 taaagttttt tttaaactaa aaatgaacaa tttgaatgtt gcaatggctg atagagaacg
    21541 actctataat tcattgcaaa atttgacttt gtattcttta ggagacattc gagatattct
    21601 gattttagtt cattattttt ttactggaaa aatagaagat ctattccatg aaccgttaat
    21661 tgaatataca gaaaatctaa gtaaaactat cgagcaaatc aaaatagata atctgttatc
    21721 acaaaattac gatccagaaa tatatctgtt tctttatgaa aataaaatac tggaatatgt
    21781 taaaaatgga gatattcgaa atttagaaaa catggttttt aatctgagta atggaataat
    21841 tccaagtgtt agtggagata cgattcggtc tgaaaaaaat tattctatca ttgtttttga
    21901 aaagttagca caaacgtcta taacattagg aatggatata atagaagcgt atcaaagtag
    21961 agatgctttg atacaagaaa acgaattagc tgtatcgtta cctgaggtct taaaagtgag
    22021 ggattctggg attgtttatt atactaagga aatcggaaaa actaagatag agcatctttc
    22081 tcccttaatt tcttctgtcg ttcaattcat cggcttaaat atctataaaa gaattactgt
    22141 aaaggaaata gctaattatt tttctgtaag tgaaactaaa ttaagagaaa gctttaagaa
    22201 tgaaatgcat attacgattt ataattatat ctctaagcga aaaatttcta cggctaaaat
    22261 aatgttgaaa tcaaaccata ctatcagtga agtttcttta ggtttaggat tttcagattc
    22321 ttcacacttt tcgagagtat tcaaaaagta cgcaggtgta tctcctaagc aatatcaatt
    22381 aggtttagtg gacaatttca acaacattag ctgagaggtt ttattttatt atgagactat
    22441 atcatttacg tagtttggag gagttgagga aattggattt taacaaaaaa tttttttggg
    22501 aaatttctga tttgagttgt ttcgtagaat ctgagcgtct aagtaatggt aataatagtg
    22561 tgttaaatga atatgacaaa gtagtaatta ataaagtaaa aagtttatgt gaagaagcta
    22621 gagaatctat cagtcatatt aatggtagca attttaaaca aacattattt aatctgatta
    22681 agctagatgc taaaatatca agttatttat tctttttgat acatgatgaa tttatggatt
    22741 atcaaaaatt ggatcagtta attgaaagag aaagctggga agattattac gtgggtctaa
    22801 ctttttcaga aaagttaaac aactacaagt taatagatta taagtatttg agtgaaagca
    22861 attaattatt catgtagagt actagacact ttaaatatgg acaattcaat tataaagaaa
    22921 aagaatcaat aatttaatga ggctgtgaca aatgtcattt tttgtttcgc taaaaacgag
    22981 tgaaaaaatg ttgataactc caatcattcg tttaagattc taggaatcat tcagaaatgc
    23041 tgtgaaaccg atactttata attataaaga aggtgatttc aaattccgaa gaaggaattt
    23101 gaagtcacct ttttacttat gtcacagtct cattcagtaa tgcgggataa ggctccttat
    23161 tccgttattt gaatactctg aagtttaatc taagaaaggg taatattttg aaaacatgct
    23221 tcatcgcata gaaatgaact taatttcaga aagaatacat acatatcttt ttatatgttt
    23281 tcagctgctg aatggttaaa aagcacaaat atccgaaaaa aacatgaaga aatgtacttt
    23341 ttttgttgta atgttcatga aattctctaa gtaaattagt taacataagg ttagtaagat
    23401 tcctattctg tgaataatac gtatcagatt tatcttttat tcttactagg aaagtaatta
    23461 ttaagggagt tgatttgaat aatggttagc aagaataata agagagtatt tctagaaaaa
    23521 acaaagaaac gagtattgaa gtacagtatc aaaaaattaa gtgttggggt tgcatctgtt
    23581 ttgattggtg ttggtcttgt cttgggaaca actgaactag ttaaagcaca agatgaaatt
    23641 tctccaagca gcccacttga aacagcgata agctccgtac aagtaggtga caaagtagct
    23701 tcggggaata cttttcagga gaatcctggt tatacgaaaa attataactt ttcggattta
    23761 caatttagtc ctcaagaact aactggagac acactaaaag gcaatacaat tggatttgaa
    23821 gtttacggaa aacataatat tgcagcatca actaaaaact gggaaatccg tcttcaatta
    23881 gatgaacgat tagctaaata tgtagaaaaa attcaggtcg atccaaagaa aggaattgga
    23941 tcttctagac ggacctttgt aagaattaat gattcgctgg gtagacctac aaatatttgg
    24001 aaggtcaatt atattcgtgc aagtgatgga ttatttgctg gggcagaaac aaccgatacg
    24061 caaaccgctc ctaatggggt aattacgttt gaaaagagcc tagatgaaat ttttaaagag
    24121 ataggcatag acaatctcaa gaccgatcgt ttaatgtatc gaatctactt ggtaagtcat
    24181 caagacgatg ataaaattgt accgggtatt gatagtacgg gctacttttt aacagattca
    24241 gatgatttct ataatagctt agatgtatct gaaaataatc ctgaccagtt taaacatgga
    24301 tcagtaagtg caaaatatga gaaacctaat actcaaacaa aagatggttc aggatccaca
    24361 ggtgctaatg gagctataat cttagatcat aagttaacga aaaattataa tttctcatat
    24421 tcatcttccg caaagggcac gccttggtat gctaattaca aaattgatga acgattagtt
    24481 ccatatgtag cgggtataca gatgcacatg gttcaggctg acaaagtaac atatgatgtt
    24541 tcgtttgaat ccggaacaaa agtagctgat ttagcaatcg agcgacggga aggtcatgaa
    24601 aattatggca taggttcaat aactaataat gatttaacta aacttatcga ttttgctaat
    24661 gcaagtccac gtccagtcgt tattcgatat gttttacaat tgactaagcc attagatgaa
    24721 atcttagaag atatgaaagc aacagcacaa gttgaagaaa ataaaccatt tggtgaagat
    24781 ttcatctttg attcttggtt gtcggatacg aataaaaaat taatccagaa cacttatgga
    24841 acaggttatt attatttgca agatattgat ggtgatggaa accctgacga taaagaagag
    24901 agcggagaca cgaatccata tatcgggaaa cctgaattag aagaagtata tgatgttgac
    24961 acaacagtta aggggaaagt attcatccac gagttagcgg gaacaggtca caaagcccaa
    25021 cttgttgata aagaaggtac tgtattagca gaaaaaacta tcgctccaaa tgaaaaagat
    25081 ggggctccaa tttcagatac tgtagaattt gaatttacgg gtgtagattc aagtaaatta
    25141 atcgcgaaag atgaattaaa aatccaaatc gtttctccag gttttgataa accagaagaa
    25201 ggttcaaccg ttattaagga atcaccaaaa gcggttgata aacaaaccgt ggtagttgga
    25261 tttaaaccag atgctaaaga atcaattcgg aataataaaa acttacctga agatgcagag
    25321 tattcatgga aaacagagcc tgatacttct aacgttactg atagtacgaa aggtattgta
    25381 actgttaaga tcggaaatcg aactttcgac gtggatgtag agtttgctgt aaaagcttct
    25441 caagctatgg aaaatgatgc aacatacgta cctataacaa caactccaga aacgacagtt
    25501 caaagtggaa aacctacatt tgataaacca gatgttcctt tagctaaaga tgccttttca
    25561 atttcagatg tctataataa ggacttcggt aatgcaagtg ttgatgcaaa cactggtatt
    25621 gttacattca ctccagctaa aggtgtagga gaatcggagc cgattactgg aacaattcct
    25681 attaaaattg tttaccaaga tggttctgta ggcacgaccg atttagcagt aactgtaagt
    25741 aaagatattt atgaaaatcc aggagaaaac attcctgcag gctaccacaa agtaaccttc
    25801 accgcagg
//
LOCUS       DAFBVQ010000039        25648 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.040, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000039 DAFBVQ010000000
VERSION     DAFBVQ010000039.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25648)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25648)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25648
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.040"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..211
                     /locus_tag="LLC22_001764"
     CDS             <1..211
                     /locus_tag="LLC22_001764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK5435043.1"
                     /translation="VAEYTRYDLQRLYVKPGCSGLWQVSDRNNVSFHKMVELDLEYIS
                     HRSLMYDLRLILKTFYVIVKPNGAY"
     gene            1438..2118
                     /locus_tag="LLC22_001765"
     CDS             1438..2118
                     /locus_tag="LLC22_001765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350621.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK5435044.1"
                     /translation="MIGIEEKKGVQKDVTIDREENLRGHRFYWIGRRAQDIFFSALAL
                     IALSPVMLITALAIVIDDPGGSPIFVQDRVGRNGKLFKFYKFRSMCVDAEAKLEALLA
                     QNEMDGPVFKIKDDPRITRVGKFIRKTSIDELPQLWNILKGDMSIIGPRPALPREVEQ
                     YGDYERQRLFVQPGLSCYWQIAPHRNELSFEEWVELDVKYINERSFITDWKIIFLTLQ
                     AVLFGYGE"
     gene            2147..3460
                     /locus_tag="LLC22_001766"
     CDS             2147..3460
                     /locus_tag="LLC22_001766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
                     /protein_id="HBK5435045.1"
                     /translation="MNIILLSGGSGRRLWPLSNDIRSKQFIKLFKDENGEYESMIQRV
                     YRQITTVDPDAKVTIATSKSQASAIHNQLGDKASICVEPCRRDTFPAILLAAAYLHDE
                     LGVGDDESVAVCPVDPYVDNSYYEGVEALEKLVQQNTANLTLMGIAPTYPSEKYGYII
                     PESSNEVSTVKEFKEKPDKATAEKYLAQNAVWNAGVFAFKLGYLLEKAHAMVDFEDYR
                     DLYSKYETLTKISFDYAVVEKETSIQVMRYNGDWKDVGTWNMMAEVMADNIKGKAVMD
                     DTCVNTQIVNELNIPILAMGCKDMVIAASGDGILISDKERSGYMKPYVEKISTEVMFA
                     EKSWGTYTVMDVQEGSMTVKVSMQAGQKLSYHYHNSRDEVWTVVAGQGKAIVDGMKQI
                     LRAGDVVTIAAGCKHTIEAVTNLDIIEVQIGETISVADKYKSSLN"
     gene            4266..5033
                     /locus_tag="LLC22_001767"
     CDS             4266..5033
                     /locus_tag="LLC22_001767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350623.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="WecB/TagA/CpsF family glycosyltransferase"
                     /protein_id="HBK5435046.1"
                     /translation="MGIEGGYLMSRMRFMNTEIDNLTMGEVLVEVEKMIQDRRCGYVV
                     TPNVDHIVQLETGKELQDVYKNASLILTDGKPLIWISKFYKTPIKEKISGSDIFSLLC
                     KMAAEKGYTMYFLGAAEGVAAKAADNLMKRFPGLNVVGTYSPPYGFEKDEDEMFKIDS
                     QIKRANPDMLIVGLGCPKQEKFMFYNCDRLGVPVSFGLGASLDFEAGNVKRAPKWMSD
                     YGFEWLFRITQDPKRMAKRYLVDDLKIFKLALKYRKK"
     gene            5060..6061
                     /locus_tag="LLC22_001768"
     CDS             5060..6061
                     /locus_tag="LLC22_001768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304640.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="kinase"
                     /protein_id="HBK5435047.1"
                     /translation="MIITKTPFRMSFFGGGTDMEDYFRENGGAVLSTTFDKYCYVNVR
                     HLPRFFDYSTELSYSRTERVTNIEDIEHPAIRNAMKMLDMHEIRLTYEADLPARSGLG
                     TSSSFAVGMLNAFYALKGKYADKKKLVDKAIYLERVLCNEAGGWQDQIAAAYGGFNRI
                     NFNSDGYEVLPIIITPERKKQLNNNLMMFFTGFTRFSSDVQKANNVSGTEDKRVRLKK
                     MYELVDEAEAVLTDKNRDLDDFGRLLDLTWRLKKATGGAISTGSIDELYEKGMAAGAL
                     GGKLLGAGGGGFLVFYVQPEKQNAVRSAMSNLMYIPFEFENGGTQVIHYTPEMYIPK"
     gene            6084..7370
                     /locus_tag="LLC22_001769"
     CDS             6084..7370
                     /locus_tag="LLC22_001769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD-IIIA family hydrolase"
                     /protein_id="HBK5435048.1"
                     /translation="MKVVIMAGGKGTRISSVASDIPKPMIKIENKPVLEHEIECLRDQ
                     GFTDIILTVSHLGDIIMNYFGDGSGISPVTGQPFDVKIEYFLEKEPLGNAGALFRLKD
                     NLTEDFLLLNADAMFDVDFNRFVAYHREKGGLVTLFTHPNSHPYDSGLIIADKDGSVD
                     RWLVKEDSRPTYYRNRVNAGLHVISPAVLDVEINTPKIDLDRQLLKPLAGTGKMFCYD
                     SPEYVKDMGTPDRYYAVCEDFKAGRVKGKNLQNKQKAVFLDRDGTINQYVGFLRHIDE
                     FELIKGTEDAVKKINAAGYLAIVITNQPVIARGEVSFEELEEIHNKMETLLGYKGAYL
                     DAVYYCPHHPHKGYEEERPELKFDCECRKPKPGMLIQAATDFNIDLSQSWMIGDGEND
                     IKAGQAAGCKTALVGESEYGQDMTIATLSEFADKIC"
     gene            7404..8057
                     /locus_tag="LLC22_001770"
     CDS             7404..8057
                     /locus_tag="LLC22_001770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5435049.1"
                     /translation="MIDNRLQKHIDLLIKRYPTLEVIKQDIVDGYLIMEECYLNDGKL
                     LIAGNGGSAADSEHIAGELMKSFKTPRPVSREFADKLIAVDPVKGSELAKNLEYGLMA
                     IPLVAHEALSTAYINDVDGLGVFAQQLFGFGRPGDVFLGISTSGNSKNVINATVVARA
                     LGMKVIGLTGAKGGELARVADVCVKAPETETYMIQEYHLPIYHCWCLMLEDKFFGNR"
     gene            8090..9295
                     /locus_tag="LLC22_001771"
     CDS             8090..9295
                     /locus_tag="LLC22_001771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5435050.1"
                     /translation="MNVLFITTQFPYPLDNGGKIGAYNGISVLSRDYDVTVLSFTEEP
                     QYVEEGVSFFREKFNSVKFENPVIHDVHIRNNPMKLVEALAIGYCLRQPYIVSKFYDS
                     KMLQLIDEKFSNNAYWDIIFIDYLNMQSYGQYIREKYKTQFGKYILKDHNIEYDLVLQ
                     EAESSRGLKKKLLQLEYKRTRKYEEAAVNRADYCFSVCDANTEVLKKINDNSYTMLPT
                     YEMLTGVKKNIEKNTILYLGNLSWKSNMQGLVWFLESIYPNIQQRIPDVKITIVGSGP
                     VGTDFSKYSGVDYRGYVKDISHIYDDQAVLIVPLLEGSGIRIKILEAFNNEIAVVSTL
                     VGCDTIGAKDGSELFIADNEKDFATAVVRLLEDMNLNEKVRKNAKLFLKEKYSLTARQ
                     DEFSAIINS"
     gene            9425..10750
                     /locus_tag="LLC22_001772"
     CDS             9425..10750
                     /locus_tag="LLC22_001772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435051.1"
                     /translation="MIVAAMSYHLTGNSNVASLIAVVGVVYAIVKACNNEYLAIWVMF
                     VLGSDIWGIVPYINIGSGVLHWSDFNVIVAIFLCLRFIKVKARSRYGIVYSVMLIFIL
                     IACVQSHSIYGQDVHTTLLTARELLVVISFWPIVKIVYSERITKNEFIDLVCKFTRWT
                     MCIYWFEWILVNMGFNITFLQTGARWGTRIYIDPIFIILYFFINLYAVIYKREGYNST
                     NKSIWNCIFSLLTFVIISQGRSGILYVVITSVIMLLISLKPSKIIRFGILGIALIACL
                     VSVTQIREVVISSFVESQSSDTGNIAYRIAEQDYFENKLEGHELFGVGIPNNHDARAV
                     EYSGKTIDFESKKYNPYYLEDLGAFEIRYRFGIIAYALYIVALAISIIDAGFRRDKSV
                     AAFAGMAFMVFMALNFNLLAYITARPFGFMISLILIEISAFNDEFIYIE"
     gene            10767..11897
                     /locus_tag="LLC22_001773"
     CDS             10767..11897
                     /locus_tag="LLC22_001773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340448.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435052.1"
                     /translation="MNLDRLKKIANMISPIIKVINAPLAYFSGKSDYMEKGILWPTVT
                     TYSNNSRKVIQYTTLPKNVDNMAQMQWAGESFEDICIVLQGPVLEDGDFTLNTVKMYN
                     KYYPKVKLVVSTWIGLSEETECKLREAGADVVLCKKPEKTGAYNINLQLTSAYEGVKM
                     AQKLGCSYALKTRTDQRLYANDVLKYFQTLLNIFPSSDCKVVNQRLIFTTYGKSFRYL
                     PFNLCDFLVYGETSELLKLYGIQRDNRASDFGKIIYTEEKEFNKKIFTLLEGKQGVSP
                     YDVFPDFDALYKKYMFAEYYIVYNYFLENIASNESYGDLMDAYYSYLKKYAVVADSEK
                     LLLYWPKYVQYNVKFENELDFYAKLDSKKWMDIYANYTPFSQ"
     gene            11923..13008
                     /locus_tag="LLC22_001774"
     CDS             11923..13008
                     /locus_tag="LLC22_001774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340449.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide pyruvyl transferase family
                     protein"
                     /protein_id="HBK5435053.1"
                     /translation="MKIGIVTIVNGASFGNRLQNYATQKVLENNGYTVETINNCFDKE
                     GTLSIVIKNAIYTLFKFIPHFKKSKSIWKRMYTFYQWDKQYIDYSHRKIDASKKNSFV
                     SIKNDYDYFLVGSDQIWNPKYAANKGFELLSFVPNEKRVSLSTSLGVPSIPSDLEKLY
                     VTEWNKFKSISVRENQAAKIIEDLTGTTAAVHIDPTLMLERSEWEAFQKKPDNIDENY
                     ILSFFLTNPPKDTVDVLDKVAKDLKIGVLTLDASWEYFQDITPNHFVYLISHARMIYT
                     DSFHCTVFSLLFGKPVVVFDRFDSEKMNSRLSTLLNKVNKAHFWVGKKADEAMIRAIA
                     SEPEYDIDKLMVSERECVKAYLKEYLQ"
     gene            13031..13846
                     /locus_tag="LLC22_001775"
     CDS             13031..13846
                     /locus_tag="LLC22_001775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340450.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435054.1"
                     /translation="MEHLSDCFGKMKIVTTSCAREYFKDDLDKSEYSCFVDSRAAMFF
                     AMGQALAKRRNVVVMLADELTSCYTALTECAFQQVDLIVFAFQTVRHEIDLASLKNCG
                     CNLINCSAQDDIDRVVSNTKGLNQTTVIKINMNCESDKDHICEYIDLPDIPVFFHGSL
                     YSPASKKKYEQYGQVSKYLGYLVGGKDAILIISHNEFLNDISVWINYYSFGEIQPKII
                     IFDSPNDYQYKWLCDLECSVAHSTNRFLSEDLALLQNNGISIVLRGDNYDIVS"
     gene            13830..15548
                     /locus_tag="LLC22_001776"
     CDS             13830..15548
                     /locus_tag="LLC22_001776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylase"
                     /protein_id="HBK5435055.1"
                     /translation="MISSVKNVQILVSLLKQHNIKDIVISPGSRDFQLVHSVETDSFF
                     RTYTVVDERSAAFFANGLSMAIDKPVCVCCTSSTASSNYMAAAKDAFANGIQLVLLTA
                     DRDYRRLYQMEDQMIDQVDMYGAYVRSNVDIPIVKDSDDEWYATRKINEAILELNHGV
                     KGPVQINYQLMDLSAPFVETMPEYRKITRYQEDDLLSSVEIFKQKLLSKKRIMVLCGQ
                     QEENNLSALLEEFFIKYNTIIIKDNYSNIHGEHFIKTVLVTERMSVNAFIDYCPDLVI
                     TIGKHVWSFVKYTLRDKKLKFEHWRISEDSKIVDPFNKLTSVFQCSAEFFMETVTAGV
                     NSNNNLEYYNLWKTRLSKVCYPELVYSNFYAISELVKKIPDSALVHSSILNAARLYDF
                     VSDDKALLSFANLGADGIDGCLPTFLGQAEADKTRPAYLISGDLSFFYAMNSLCGDIP
                     DNAHIFLINNHSGSEFHTNFGKFYNGSLSVDKHIAAGHISNAKDWALENNIKYITADS
                     KESLKSGLDVFINTFDSPVLFEVFTDPDTDTSVLESFYSINKVITPKMYFRKALDIIK
                     KHLHIK"
     gene            15574..16410
                     /locus_tag="LLC22_001777"
     CDS             15574..16410
                     /locus_tag="LLC22_001777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5435056.1"
                     /translation="MAIKSYIKRLLLYIRHGDPKINLDVSYLSEGAMLAGKTVIITGG
                     AKGLGFAIAKSFIAQGASVIITGRDMDSLNNAKCQLGDMCSIRAFDITDAKMYRTFFE
                     DAYETFGRIDILLNNAGISLHEDGFMSVTEKTWDKQMDTNLKGVYFFTQEFIKFVKEK
                     NQMQANIIMMSSERGLCGDSIPYGLSKAAINSLVVGLSKKYISEGIRVNGIAPGVTAT
                     AMTGISEKGNLYNPATIGYRYFLPEEVAQVALFLASSLSNCISGEIIACDQGQYLSRN
                     WG"
     gene            16415..17848
                     /locus_tag="LLC22_001778"
     CDS             16415..17848
                     /locus_tag="LLC22_001778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBK5435057.1"
                     /translation="MGILLKKYNSLSEPAKASIWFTLCNVLQKGILFLTTPIFTRMLS
                     TAEYGKYTIFISWYSIIAIFTTLNLSAGVYNKGLIKYENKYALTSSFLGLSSFISLCA
                     LMLYLPFRTVINGLLDLSTEFVILILIESIFEPAFLLWSVKERFDYKYQKLVLITVLM
                     AVLNPGLGIILILSFGEYAIWRVRAYVVVNVVVGMFIGIGILAKGKKLFDKEYWTYAL
                     RFNLPLIPHYLSMTLLNQVDRLMINSMVGASEAAIYSIAYTISSMMNIITTAINGSFI
                     PFTYKAIKDGVYEKIKSVANQLLVLIFVLCSFTMLFGPELIWVVGGEKYMDAVWIIPP
                     VAASVFFMFLYPLFGNIEFYYEKTNYVMFASCVGSIAKIISNYVSIPRFGYISAGYTT
                     LICYMLFSFAHYMFYKKILRENGIKEDMYNIKNIIFLSVLMIVLTIGMTILYFSTILR
                     YSIIIGLVIVAFLKRTQIMKILKNIKN"
     gene            17886..19526
                     /locus_tag="LLC22_001779"
     CDS             17886..19526
                     /locus_tag="LLC22_001779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBK5435058.1"
                     /translation="MRLLIPSAKIVPEELHHLGKLPAIIYPINQKIVFDYLYDQYKDV
                     CSAIDIACYEKMDKVARRLDKYIKSKTVNIIQLKELGDLGRTIYDSLIGCDEPVIINF
                     ADTIINDNIYSLECDSFFYAEDYYSNTWTFFEEKDGDIISVLDKNELKEDDGKKHKLF
                     SGVFQIMDAQYFRECLRKALMSNVVNVNSFYQALQEYSKRYEFLSIKTNNWFDIGHAD
                     KYYNSKLEVKAREFNHISIDKDRSILRKISEDVEKFIGEIKWYLKLPAQVEYVRPRIF
                     EYSTSYINPYVSMEYYSYHTVHELFLYSDLTKKQWIDIFNRIRFVCSDFKRYSVSGDN
                     IQKSLKDMYLDKTFQRFNKLRKDPRFTEFFSSDIQINGVRYKSLDQIEALLSVSVPRE
                     LFDITQFNIIHGDLCFANIMVDNTFSFIKVIDPRGKFGDFDIYGDYRYELAKLFHSVD
                     GKYDFIIKDLFTIKYDPKKAIIDYIVQDRKRDYDLYEVFYSVFKDEIGSDLKKIELIE
                     ALLFLSMIPLHGESLNHQMAMLATGLEILGRVVPDIYC"
     gene            19614..20012
                     /locus_tag="LLC22_001780"
     CDS             19614..20012
                     /locus_tag="LLC22_001780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="capsular biosynthesis protein"
                     /protein_id="HBK5435059.1"
                     /translation="MFKDYAFVFDIDGTLCPIKKKDEKYEDLVPYANMVEKLRYYKEN
                     GAKITLFTSRNMNSYHGNLGVINANTAKILLAWLDKWEIPYDEILYGKPWPGHKGFYV
                     DDRTVRPDEFLSCTLDQLDEICKKSKLKSE"
     gene            20037..20753
                     /locus_tag="LLC22_001781"
     CDS             20037..20753
                     /locus_tag="LLC22_001781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5435060.1"
                     /translation="MTVIITMAGLGSRFRKVGYTVPKFMIEAKGKTLFDWSLDSLLDY
                     NSHVEKYVFVVRKEDDATVFIKEHCSLYGIENVEVVEIDYMTDGQATTCMLAIPYCAP
                     DNAIMVYNIDTYVEPGEMKYVDISGEGHIPCFHADGDHWSFAKLNEYGDVVEVREKVR
                     ISNNCTLGAYYFSSAKLYASLYEEYYADERHLEKNEKYIAPLYNYMIEKGMKVTISIV
                     DKSKVHVLGTPEELDVFLNE"
     gene            21985..22564
                     /locus_tag="LLC22_001782"
                     /pseudo
     CDS             21985..22564
                     /locus_tag="LLC22_001782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317850.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="VanZ family protein"
     gene            22624..24276
                     /locus_tag="LLC22_001783"
     CDS             22624..24276
                     /locus_tag="LLC22_001783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phospho-sugar mutase"
                     /protein_id="HBK5435061.1"
                     /translation="MDHNANYYHWLTNANAEIVEELRSYSEKDIEDSFYKNLSFGTGG
                     LRGTIGAGTNRMNVHTVGKASQGLSDYLNKTYETPSVVVGYDSRIKSDVFAKVAADIF
                     AANGIQVHLWPELLPVPTVSFAIRYLKASAGVMITASHNPSKYNGYKVYGAGGCQITT
                     EAAAEILAEIEKLDIFADVKMGGDASRIASIQPEVLTAFIEEVKGQSVLFGEEVDKNV
                     AIVYSPLNGTGLVPVTRTLAEMGYSNVTVVEEQRLPDGNFPTCPYPNPEINEAMSLGM
                     EYAKKYNADLLLATDPDCDRVGIAVKNAEGDYVLLSGNETGLLLLDYICSQRIKHGKM
                     PTDPVMVKTIVTMDLGERIASNYGVRTVDVLTGFKFIGEQIGMLEKAGKVDSYIFGFE
                     ESYGYLSGSYVRDKDGVNAAYLICEMFSYYKTQGISLFDKLNEIYAKYGYCLNTLHSF
                     EFEGAAGFTKMQKIMVEFHKGLDMIGGKKVIETLDYSTGLNGLPKSDVLKYLLEGNCS
                     VVVRPSGTEPKLKTYISVSAESKEAAEVMEAVMAAELAEMFK"
     gene            24620..24985
                     /locus_tag="LLC22_001784"
     CDS             24620..24985
                     /locus_tag="LLC22_001784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyltransferase family protein"
                     /protein_id="HBK5435062.1"
                     /translation="MYYFQQSYLPAILNKAISIGDTGVHIFFFCSGFGLYLSYLKKPI
                     TLGEFLQKRFIKIYIPYIIVITVSVLLPYMTQDLNAAKVYLSHVLLFKIFLPVYEESL
                     GPFGLFRQLFSSISYSYQL"
     gene            25073..25516
                     /locus_tag="LLC22_001785"
     CDS             25073..25516
                     /locus_tag="LLC22_001785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304670.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435063.1"
                     /translation="MEAYEFLGAALRNIFGNLLSACLVAEYLVKRKIVRFNNIFVIMA
                     SIVGIGFAGISKIIGGLMESINDIFAFFGYGAIAILMYQVIPFRKIMPRISRYSYDIY
                     LLHILVFSTIHQIIPNLVLAAFVSIPITLVLSYYYSIMLYRLKLK"
BASE COUNT         8213 a         3591 c         5548 g         8296 t
ORIGIN      
        1 agtagctgag tacacgagat atgatcttca acgcttgtat gtaaaacctg gttgttcagg
       61 tttgtggcaa gttagtgata gaaataatgt tagtttccat aaaatggttg agttggattt
      121 agagtatatt agtcatcgaa gtttaatgta cgacttgagg ttgattttaa aaacgtttta
      181 tgttattgtc aagcccaatg gagcatatta gttagggata gaatgatgga ttgttaataa
      241 aaaagattac acatgttcat attatcgttt caaaagtaat aactgtaatt atggagggtt
      301 tgaatcactt gtagaaaatc taaaaaaaga aaggtgaatg gggcaattca gtatcattat
      361 tcttatataa aagaaaatat tcgaaatttt gggatgatac cactcttaaa tataatgatc
      421 taaatgcttt aatattggta tatccgatat aggaactgac gagctattta gtatgataca
      481 aaagtatatt gatagccatt aataaatttt ccaaaaaata atgacagcac accaattttt
      541 ataatttagc ttgttgaatc ggtatgttca tgggacggtt caaaaaaaga atcgaaaaaa
      601 taaacggtaa aattttagtg aatcctatgt aataaaattt ggatagatgg aaaaacagca
      661 cataaggagg ctgagtttgt tgtcatttct gctcctacaa actatggtag tgaatgtgtt
      721 attgaattag tgatgtctgt tacttcagag acattgggga taattaactt cactatacct
      781 gtagggtata caaaaaatgg aagaaaaaat attatcaata gattttattt agttcagaat
      841 ttttacgtgg aagtaaatta ttgatgataa tctttatcca attagaatta ttatcgtagg
      901 atgtgatgat gatagccgtg aagttgttca agtatttacc aatgtctaca acgcagaaaa
      961 ttagtttggg tttttcggat tggaaaattt caatgtataa aatcataaat ttgctgtaaa
     1021 tagacagttt ggggtagtaa tagcccaata aattgttcga taaactcatc tttggggtga
     1081 gaatagctca atcattgaat ttcaaacctg cctttggggt gggattagag gtcaatatgt
     1141 acctacataa tactttttgg aaaatgatgg tgttgagaat gtaagtacat ttcaatgtga
     1201 aattctaata tagccccaaa cgaggtcaat aaaaatgacc taaactcgta tttctcccct
     1261 aaacgaggag gagatagata tgaaaattga atgtgccggc gttggagttg gctgctttta
     1321 gtaggaatga acatggttcg atgagaactg tttcagatag agtggtcgat gatcacaggc
     1381 ctttaagtcg tttacagatg atgagacttg taaaaataga gggacgaatg gaaaaagatg
     1441 attggtatag aagaaaagaa aggtgttcag aaagacgtaa caattgatag ggaagagaat
     1501 cttaggggac atagattcta ttggattgga cgcagagcac aagatatctt cttctcggct
     1561 ctagctttga ttgcattgag ccctgtgatg ctaattacag cgctcgccat tgtgattgac
     1621 gatcccggtg gcagcccgat ttttgtgcag gatagagttg gaagaaatgg aaagctgttc
     1681 aagttttata aattccgatc tatgtgtgta gatgctgaag caaaattaga agccttgttg
     1741 gcacaaaacg agatggatgg tccggtcttc aagattaaag atgacccaag aatcacgaga
     1801 gttggtaaat ttattcgaaa gacaagtatc gatgagttac ctcagctctg gaacattctt
     1861 aaaggtgata tgagtattat tggacccaga cctgctttac cgagagaggt ggaacaatac
     1921 ggtgactacg aaaggcagcg gttgttcgta cagcctggtc ttagttgcta ttggcagatt
     1981 gctccacatc gtaatgaact gtcctttgaa gaatgggtgg aacttgatgt gaagtacatc
     2041 aatgaaagaa gctttatcac ggactggaag attatcttct tgactttaca ggctgtatta
     2101 tttggatatg gtgaatgatt atatatagta ttaggagttg aaatatgtga atattatttt
     2161 attatcgggt ggtagcggta ggcggttatg gccgctgtcc aacgatattc gtagcaaaca
     2221 attcatcaaa ctgtttaagg atgaaaatgg cgaatatgaa tctatgattc aaagagttta
     2281 tcgccagatt acaactgttg acccagatgc aaaggtcact attgcaacaa gtaagtctca
     2341 ggctagtgca atccataatc agttgggaga taaggcttcg atttgtgtag aaccttgtcg
     2401 tagagatact ttccctgcaa ttttgttagc tgcagcatat cttcacgatg aacttggcgt
     2461 aggtgatgat gaaagtgttg cggtttgtcc tgttgatcct tatgtagata attcctatta
     2521 cgaaggcgtt gaagcccttg agaagttggt gcagcagaat acggctaatt tgactttgat
     2581 gggtattgca cctacatatc ctagtgaaaa gtacggttat atcatccctg aaagttctaa
     2641 cgaagtaagt actgttaagg agtttaagga aaaacctgac aaagcaacgg cagagaaata
     2701 tttagctcag aatgctgttt ggaatgccgg tgtatttgcg ttcaaacttg gttacctgtt
     2761 ggaaaaagct cacgcaatgg tggattttga agattatcgt gatttgtatt ccaagtatga
     2821 gactttaacc aagatcagct ttgactatgc tgtggtcgaa aaagaaacga gcattcaagt
     2881 gatgcgttat aacggggatt ggaaagatgt cggaacttgg aacatgatgg ctgaagttat
     2941 ggctgataat attaagggga aagctgtaat ggatgatacc tgtgttaata ctcagattgt
     3001 gaatgagttg aatattccta ttcttgctat gggctgcaaa gatatggtaa ttgcagcaag
     3061 tggcgatgga attctgattt ctgataaaga gcgcagtggc tatatgaagc cgtatgttga
     3121 gaaaatcagt acggaagtaa tgtttgcaga aaaatcctgg ggtacatata ccgttatgga
     3181 cgttcaggaa ggctccatga ctgttaaagt ttctatgcag gccggacaga agttgagcta
     3241 ccactaccac aattctcgcg atgaagtttg gactgttgta gcaggacagg gtaaagcgat
     3301 tgtagatggt atgaagcaga ttcttcgtgc gggtgatgtg gtgactattg ccgcaggatg
     3361 taaacataca atcgaagccg tgacaaatct ggatattatc gaagttcaga ttggtgaaac
     3421 tattagcgtc gctgacaagt ataagagttc tttgaactaa aagttcgcga ggtagttatt
     3481 atggagatac taaaatttca acccgtgggt aaagattatc tttggggtgg agaacggttt
     3541 aagacggaat ttggaaaaaa ttgacttaac accattaagc ttatacgtgg gaatgcttag
     3601 ttcatctaga cgataactac gtacggaaat atcaaatatg aaggacagaa tggtaaaacc
     3661 gagttgtggt atgtattgga agctacaccg gggggtgatt tatgcttttg agtacgatgt
     3721 aacagaagaa atgttacgaa atgctgtgat ggacagatca cttgggaaac atttatataa
     3781 agaagaagta cacaagggag atctttttta tgtcagttca tggtattggc gctggagtat
     3841 tagtggctga aatacaggaa agctcaaatg ttacctatcg agtttacgat tatgatcgag
     3901 tagataagaa tgataataag tgagaattgt actttgaaaa agcgattcag gtaatgaata
     3961 tggaagccac tttgaaattg gagaaaagaa ataagctcat tcatttttat cctggtggct
     4021 ctcgtgaaat actgtgtaga tgtaaatact gtgagcccga aagaatccaa gtaaagacgg
     4081 ggttttcgtt ctcggtaaaa gaggaatctt ttcaagttct tttatgtata tcgggggacg
     4141 gacaagttga gtcggcaaat ggtgttatga aactcattag atttgtaaaa aagatattgt
     4201 atgtttttgc caacgaatat tggaagatgt taagtgttga gcgatgcgga cttactgaaa
     4261 attagatggg gatagaggga ggatatctaa tgtcacgaat gagatttatg aacacagaaa
     4321 ttgacaatct tacaatgggt gaagtattgg tagaggttga aaaaatgatt caagatagga
     4381 gatgcggata tgttgtaact ccgaatgtgg atcacattgt tcagttggaa acaggaaaag
     4441 agttgcaaga tgtttataaa aacgcatctt taattttgac ggatggtaaa ccattgattt
     4501 ggatttcaaa gttttataag acaccaataa aagaaaaaat atcgggatcc gatatatttt
     4561 ctttactgtg caagatggct gcagaaaagg gatacacaat gtatttttta ggtgcggcag
     4621 agggcgttgc ggctaaagcg gcagataacc tgatgaaaag atttccggga ttaaatgttg
     4681 taggaacata ctctcctcct tatgggttcg aaaaagacga agatgaaatg tttaaaattg
     4741 attcccaaat taaacgagca aatccagata tgcttattgt gggtttgggt tgccctaaac
     4801 aggaaaaatt tatgttttat aactgtgata gattgggagt acctgtgtct tttggtctag
     4861 gagctagttt ggactttgag gcagggaatg ttaaaagagc accaaaatgg atgtcagatt
     4921 atggatttga gtggctgttt agaattactc aggaccctaa aagaatggca aaacgatatt
     4981 tggttgatga tttaaaaatc tttaaattag cactaaaata tcggaaaaaa taaactatat
     5041 tcaatgagga caatgaagta tgattattac aaaaacacct tttcgcatgt ctttttttgg
     5101 cggcggaacg gatatggaag attattttcg agaaaatggc ggtgcagtgc tttccactac
     5161 ttttgataag tactgttatg tgaatgtgcg tcatttgcct agattttttg attacagcac
     5221 agagttatca tattctcgta ctgagagagt aacaaatatt gaagatatcg agcatcctgc
     5281 aattcgtaat gcgatgaaaa tgctagatat gcatgaaatt cgccttacat atgaagcaga
     5341 tcttcctgca cgttctggtc tgggtacatc tagttctttt gccgtaggta tgttgaatgc
     5401 tttctatgct ttgaagggca agtacgctga caagaagaaa ctcgttgata aagcaattta
     5461 tcttgaaaga gtcctttgta atgaagcagg cggatggcaa gatcagattg cagcagctta
     5521 tggtggcttt aaccgaatca atttcaactc agatggctat gaagtattgc ctattattat
     5581 tacgcctgag cgtaaaaagc agcttaacaa caacttgatg atgttcttta ctggattcac
     5641 cagattttcc tctgatgttc agaaggcaaa taatgtcagc ggcacagagg acaaaagagt
     5701 aagactgaaa aaaatgtatg agcttgtgga tgaagcagaa gcggttctga ctgataagaa
     5761 cagagatcta gatgatttcg gcagactgct tgatctcact tggagattga aaaaggctac
     5821 cggtggtgcg attagcactg gaagtatcga tgaactttat gaaaagggca tggctgctgg
     5881 tgcattgggc ggtaaacttc tcggagcagg tggcggcggt ttcttggttt tttatgttca
     5941 gcctgaaaaa caaaatgctg tgcgttcggc aatgagtaat ttgatgtata ttccgtttga
     6001 atttgaaaac ggtggaacac aggttattca ttacacaccg gaaatgtata ttccaaaata
     6061 aagaaatcag cgaggataag aatatgaaag ttgttattat ggcaggcggt aagggaactc
     6121 gcatctcatc ggttgcaagc gatattccaa agcccatgat taaaattgaa aacaaaccgg
     6181 tattggagca cgaaatcgaa tgtctgagag accagggatt cacagatatt attcttaccg
     6241 ttagccatct tggcgatatc attatgaact attttggcga tggttctgga atttcaccag
     6301 ttactggtca gccctttgac gttaaaattg aatacttttt ggagaaagag ccattaggaa
     6361 atgccggtgc attgtttcgt ttaaaggata atttgaccga agacttcctc ctgctgaatg
     6421 cagatgcgat gtttgacgtt gatttcaacc gatttgtagc atatcaccgt gaaaagggtg
     6481 gcttggtgac attgtttact caccctaaca gtcatccata tgacagcggt ctaatcattg
     6541 cagataagga tggctctgta gacagatggc ttgtaaagga agattcccgt ccaacttatt
     6601 accgtaacag agtaaatgcg ggactccatg tgattagtcc tgctgttctt gatgtcgaga
     6661 taaacacacc taagattgac ttggaccgtc agttattaaa gccgttggca ggaaccggaa
     6721 aaatgttctg ctatgatagt ccagaatacg taaaagacat gggtacccct gatcgttatt
     6781 atgctgtctg tgaagatttt aaggctggaa gagtgaaggg caaaaatctt cagaataagc
     6841 agaaagctgt tttccttgat cgtgatggaa cgattaatca atatgttggc tttctgcgtc
     6901 atattgatga gttcgaacta atcaagggta ctgaagatgc agtgaaaaag atcaatgccg
     6961 ctggatatct ggctattgta ataacgaatc agccagtaat tgcaagaggt gaagtttctt
     7021 ttgaagaatt ggaagagatc cataacaaaa tggagacact tcttggatat aagggcgctt
     7081 atttggatgc agtttattat tgcccgcatc atccacataa gggatatgag gaagagcgcc
     7141 cagagctaaa attcgattgt gaatgcagaa agccaaagcc cggaatgtta attcaggcag
     7201 ctacggactt caacatagat ttgagtcagt cttggatgat tggcgatggc gagaatgata
     7261 ttaaagcggg ccaagccgcc ggctgtaaga ctgcattggt tggcgagagt gagtatggac
     7321 aggatatgac catagcaacc ctgagtgaat ttgcagataa gatctgctaa gggatgtttt
     7381 atcacgaaag gagagtataa acaatgatag acaatagatt acagaaacac attgatttgc
     7441 tgattaaacg ctatcccact cttgaagtaa tcaagcagga tattgttgac ggatacctga
     7501 ttatggagga atgctattta aatgatggca agctgctgat agcaggaaat ggcggatctg
     7561 ctgctgattc cgagcatatt gcgggtgagc tgatgaaaag ctttaagacg cctcgccctg
     7621 ttagtaggga atttgcagat aaattgattg cggttgatcc tgtaaagggt tctgaattag
     7681 ctaagaatct tgaatatggt ttgatggcga ttcctctcgt tgctcatgaa gcgctttcca
     7741 ctgcgtatat taatgatgtt gatggcctag gtgttttcgc acagcagttg tttggatttg
     7801 gaagacctgg cgatgtattc cttggtattt cgacatccgg caatagcaaa aatgtgataa
     7861 atgcaactgt tgttgctaga gctcttggta tgaaagtaat tggcttaact ggagccaaag
     7921 gtggagaact tgcaagggta gcagatgttt gtgttaaagc tcctgaaaca gaaacatata
     7981 tgattcagga gtaccatttg ccaatttacc actgttggtg tctaatgttg gaagataaat
     8041 tttttgggaa tagataaaat atctaagccc atattgaaag gataaaatta tgaatgtact
     8101 atttataaca actcaatttc catatcctct agataatggc ggaaaaattg gtgcgtacaa
     8161 cggtatcagt gttttatcta gagactacga tgtgacggta ttgtctttca ccgaagaacc
     8221 gcagtatgtt gaagaaggtg tcagtttttt tcgagagaaa tttaatagtg taaaatttga
     8281 aaatcctgtg atacatgatg tacacataag aaataatcca atgaaattgg tagaagcttt
     8341 agcaataggg tattgtctac gccaacctta tatagtttca aagttttatg attcaaaaat
     8401 gctgcagtta atagatgaaa aattttctaa caatgcatat tgggatatca tttttattga
     8461 ctatctgaat atgcaaagtt atggtcaata catacgggag aagtataaaa cacaatttgg
     8521 taagtatatc ttaaaagacc acaacataga atatgattta gtcctacagg aagctgaatc
     8581 aagtcgaggt ttaaaaaaga agttgcttca gttagagtat aagcgtactc gaaagtatga
     8641 agaggccgca gtaaataggg ccgattattg ctttagtgtg tgtgatgcaa atacggaagt
     8701 actgaaaaag attaatgaca acagttatac gatgcttcca acttatgaaa tgcttacagg
     8761 ggtgaaaaaa aatatagaga agaacacgat cctatatttg ggtaaccttt cttggaaatc
     8821 caatatgcaa ggattagttt ggtttttaga gtcaatttat ccaaatattc aacaaagaat
     8881 tccggatgta aaaatcacaa ttgtcggtag cgggccagtt ggaacagatt ttagtaaata
     8941 ttcaggcgtg gattatcgtg ggtatgtaaa agatatttca cacatttatg acgatcaagc
     9001 ggtgctaatt gtacctttgt tagaaggtag tggtataaga ataaaaatat tagaagcgtt
     9061 caataatgaa attgcagttg tatctacatt agttgggtgt gatacgattg gcgcaaaaga
     9121 tggaagtgag ttatttatag cagataacga aaaagatttt gcaacggctg tagttagact
     9181 gcttgaagac atgaatttga atgaaaaagt aagaaagaat gcaaaattat tcttaaaaga
     9241 aaaatactcc ttaacggcta gacaagatga gtttagtgcg ataattaaca gctaatatat
     9301 atataagctt atctgatgat gatttatagg aggaaatata tggagatggc tgagagaaag
     9361 gaaaagaaac ttggaaataa gaatatcata ttattttaga aaactcctgt tattttatgt
     9421 ttgtgtgatt gttgcggcta tgagttacca ccttacaggc aattccaatg tagcgtcatt
     9481 aattgctgta gtaggagtag tttatgctat tgtaaaggcg tgtaataacg agtatctggc
     9541 tatatgggtt atgtttgtat taggttctga tatatggggg atagtgccat atattaacat
     9601 tggtagtggt gtgttgcatt ggtcagattt taatgttata gtagcgatat ttctctgctt
     9661 gagattcatc aaagttaaag ctaggagtag atacgggatt gtctatagtg taatgcttat
     9721 atttattttg attgcatgtg tgcaatcgca ttcaatctat ggacaagatg tacatacaac
     9781 gctcttaaca gctagagaat tgctagttgt aatatccttt tggccgatag taaaaatagt
     9841 atattcagaa agaataacta aaaatgaatt cattgattta gtgtgtaaat tcacaagatg
     9901 gacaatgtgt atatattggt ttgaatggat tcttgttaat atgggattca atataacctt
     9961 tttacagaca ggtgcacgct ggggtactag aatctatata gatccgatat ttatcatttt
    10021 atatttcttt ataaatctat atgcggttat atataaaaga gagggctata atagtacaaa
    10081 taaaagtata tggaattgca tttttagttt actgacattt gttataatct cgcaaggcag
    10141 aagtggtata ttatatgtag taataacctc ggttattatg cttttaattt cgcttaaacc
    10201 atccaagatt attagatttg gtatattagg aattgcctta attgcatgtc tagtgtctgt
    10261 gacccaaatt agagaggtcg ttatatcttc gtttgtagag tctcagagca gtgacacagg
    10321 taatatcgca tatagaattg ctgaacaaga ttattttgaa aataaattag aaggtcatga
    10381 actatttgga gttggtatac caaacaatca tgatgccaga gctgtagaat attcaggcaa
    10441 aacaatagat tttgagtcta aaaaatataa tccctattat cttgaggact taggcgcttt
    10501 tgaaattcgt tatagatttg gtataattgc atatgcgtta tatatagttg ctttagctat
    10561 aagtattata gatgccggat ttcgaagaga caaatcggtc gccgcatttg cgggtatggc
    10621 attcatggtg tttatggcgc ttaattttaa tttgctagcg tatattacag caagaccgtt
    10681 cggatttatg atttctttaa ttttgataga aatatcggca ttcaatgatg aattcatata
    10741 tattgaatag gtaagggaga gcacagatga atttagatcg attaaagaaa atagcaaata
    10801 tgatttcacc aatcataaaa gtgataaatg cgccgttagc gtattttagt gggaaatcag
    10861 attatatgga gaagggaata ttgtggccta ctgtaacaac ctactccaat aacagtagaa
    10921 aagtgattca atatacaact ttacctaaaa acgtagacaa catggctcaa atgcaatggg
    10981 ctggggaaag ttttgaggac atatgtatag ttcttcaagg tccagtatta gaagacggtg
    11041 attttacact aaataccgtt aaaatgtata ataaatacta tcctaaagta aaacttgtag
    11101 tgtctacttg gataggatta tctgaagaga cagaatgcaa gttgcgtgaa gctggtgcag
    11161 atgttgtatt atgcaagaaa cctgaaaaaa caggtgcgta caatattaat ctacaactta
    11221 cttctgcata cgaaggcgta aaaatggcgc aaaaactggg gtgtagttat gcgctgaaaa
    11281 cgcgaactga tcaaagacta tatgcaaatg atgtactaaa gtatttccaa acattattga
    11341 atatttttcc atcttcggac tgtaaagtag tgaatcagcg attaatattt acgacttatg
    11401 gaaaatcatt tagatatctt ccgtttaatt tatgtgattt tttggtatac ggagaaacta
    11461 gtgaattatt aaaattatat ggtattcaaa gagataaccg agcatcagac tttgggaaaa
    11521 ttatttatac tgaggaaaaa gagtttaata aaaagatatt tacactacta gaaggaaaac
    11581 aaggtgtatc tccatatgat gtttttccag attttgatgc actatataaa aaatatatgt
    11641 ttgcagaata ctatattgtg tataattatt tcctggaaaa tattgcaagt aatgaatctt
    11701 atggtgactt aatggatgcc tattatagtt atttaaagaa atatgcagtt gttgctgatt
    11761 cagaaaaatt gttactatat tggccgaaat atgttcaata taatgttaag ttcgaaaatg
    11821 aacttgattt ctatgcgaag ttggattcaa aaaaatggat ggatatttat gctaattata
    11881 caccttttag tcagtgatta tatggaaagg atgaggtgaa taatgaaaat cggaatagtg
    11941 actattgtta atggggcaag ttttggtaac agattacaaa attatgcgac tcaaaaagtg
    12001 ttggaaaata acggctatac agttgagaca attaataatt gttttgacaa agaaggtacc
    12061 ctatccattg ttatcaaaaa cgctatttat acattattta agtttatacc gcatttcaaa
    12121 aagtcaaaaa gtatctggaa aagaatgtat acattttatc aatgggacaa gcagtatata
    12181 gattattctc atcgtaaaat tgatgcatct aaaaaaaaca gctttgtgag tataaagaat
    12241 gattatgact atttcttggt tggtagcgat caaatttgga atccaaaata tgcagccaat
    12301 aagggatttg aacttttatc atttgttcca aatgaaaaaa gagtttcatt atcaaccagt
    12361 ttgggagttc catctatacc aagtgattta gaaaaattat atgtgacaga gtggaataag
    12421 tttaaatcaa tatcggtacg tgaaaatcaa gcggcaaaaa taattgagga cttgacaggc
    12481 acaactgcgg ctgttcacat tgacccaact ttaatgttgg agcgttcgga atgggaagcc
    12541 tttcaaaaaa aaccagacaa tattgatgaa aattacatct tgtcgttttt cttaactaat
    12601 ccgcctaagg atactgttga tgtattagat aaggtcgcta aagatttgaa aataggtgtt
    12661 ctcaccttag atgcgtcttg ggaatatttt caagatatta ctccgaatca ttttgtttat
    12721 ttgatttcac atgcaagaat gatttataca gattcattcc actgcacagt tttttcattg
    12781 ctatttggaa aaccggttgt ggtatttgac cgttttgata gtgaaaaaat gaattctagg
    12841 ttaagtacat tgttaaataa agtaaataaa gcacattttt gggtaggaaa aaaagctgat
    12901 gaagcaatga ttcgtgcaat agcatctgaa cctgaatatg acatagataa gctgatggta
    12961 tcagagaggg aatgtgtaaa agcttatctt aaagagtatt tacagtaaaa ttttgaaatg
    13021 ggatgaaaat atggagcatt taagtgattg ttttggtaaa atgaagattg ttacgacttc
    13081 atgcgcaaga gaatatttta aggatgattt ggataaatca gagtattcat gttttgttga
    13141 ttctcgagca gctatgtttt tcgcaatggg acaagcttta gctaaaagaa ggaatgtagt
    13201 tgtaatgctt gctgatgaat tgacatcgtg ttatacggca ctaacagaat gtgcatttca
    13261 acaagttgat ttaattgtgt ttgcttttca gacagtcaga catgaaattg atttagcatc
    13321 tttgaagaat tgtggttgca atctaattaa ctgtagcgcc caagacgata ttgatagagt
    13381 tgtgtccaac actaaggggt taaatcagac aacagtaatt aaaatcaata tgaattgtga
    13441 gtcggataaa gatcatatat gtgagtatat agacctgcca gacatacctg tttttttcca
    13501 cggtagctta tactcacctg caagtaaaaa gaaatatgag cagtatggac aggtatcgaa
    13561 gtatttaggc tatctcgtgg ggggaaaaga tgcaatactc ataatttctc acaatgagtt
    13621 tttaaacgat atcagtgtat ggattaatta ttattctttt ggagaaattc aacccaaaat
    13681 tattatattt gacagtccga atgactatca atataaatgg ctgtgtgact tagaatgcag
    13741 tgtagctcat tcaaccaacc gatttttgtc tgaggattta gccttattgc aaaataacgg
    13801 aatttccatt gtgttaagag gtgataatta tgatatcgtc agttaaaaat gttcaaattt
    13861 tagtatcttt attaaaacag cataatatta aagatatagt tatctcgcca ggtagtagag
    13921 attttcaatt ggtgcatagt gtagaaacag acagtttttt tagaacctat acggttgtag
    13981 atgagcgcag tgctgccttt tttgctaatg gactttctat ggcgattgat aagcccgtgt
    14041 gtgtatgttg tacttcttca actgcctctt caaattatat ggcggcagct aaagatgctt
    14101 ttgctaatgg catccaactt gtacttctta ctgctgatag agattaccgc cgcttatatc
    14161 agatggaaga tcagatgatt gatcaggtag atatgtatgg ggcttatgtg cgttctaacg
    14221 ttgatattcc tattgttaag gattctgatg atgaatggta tgctaccaga aaaataaatg
    14281 aagcaatatt ggagttaaat catggcgtta agggtcccgt gcagattaat tatcaattaa
    14341 tggatttaag tgcgccgttt gttgagacca tgccagagta tcgtaaaatt acaagatatc
    14401 aagaggatga tttactgtca tcagtagaga tttttaaaca gaaactatta tcaaaaaaga
    14461 gaataatggt tttatgtgga cagcaggaag aaaataattt aagtgcctta ttggaagagt
    14521 tctttattaa atataataca attataatca aggataacta ttctaatata cacggtgaac
    14581 actttattaa gactgttcta gtaacagaaa gaatgagtgt aaatgcattt attgattatt
    14641 gcccagattt ggtaataact attggtaaac atgtatggtc ttttgtgaaa tatactctta
    14701 gagataaaaa gcttaaattt gagcattggc ggatatctga ggatagtaag attgttgatc
    14761 cgttcaacaa gctaacatct gtctttcagt gctcagcgga attttttatg gagactgtca
    14821 ctgctggtgt gaatagcaat aataatcttg agtattataa tctatggaag acaagattat
    14881 caaaagtttg ctatccagag ttagtctata gcaattttta tgcaatttca gaactagtaa
    14941 aaaaaattcc agatagtgca ttagttcatt ctagtatttt aaatgcggct agattgtatg
    15001 actttgtatc tgatgataaa gcattactca gttttgctaa tttaggggct gatggtattg
    15061 atggttgttt accaacattt ttaggtcagg cagaagcaga taaaactcga cctgcgtatt
    15121 taatttcagg agacttgagt ttcttttatg ctatgaatag tttatgtggt gacattccag
    15181 ataatgcaca tattttcctt attaacaatc attctggaag tgaattccat acaaattttg
    15241 gtaagtttta caacggatca ttaagtgttg ataagcatat agctgcagga catatttcaa
    15301 acgcaaagga ttgggcatta gaaaataata taaaatacat tactgcggat tctaaggaaa
    15361 gtctcaaatc ggggttggat gtatttatta atacatttga cagtcctgtt ttatttgagg
    15421 tctttacaga tccggatacg gatacgtctg ttctggaatc tttttatagt ataaataagg
    15481 taatcacacc aaaaatgtat tttagaaagg cgttagatat tataaaaaag catttacaca
    15541 ttaagtagat gtttattgcg aggtgaaaca aatatggcaa taaaatctta tattaaacgg
    15601 ttattgcttt atatccgtca tggagatccc aaaataaatt tagatgtgag ttatttatct
    15661 gaaggtgcaa tgcttgctgg taagactgtg ataattacgg gtggtgcaaa aggacttggt
    15721 tttgcaattg caaaatcatt tatagctcaa ggcgcaagcg ttattattac aggaagagac
    15781 atggattcgt tgaataatgc taaatgtcag cttggagata tgtgttctat cagggcgttt
    15841 gatataactg atgctaaaat gtatcgaacg ttttttgaag atgcatacga gacctttgga
    15901 cgtattgata tactgcttaa taatgctggg atctcgttac acgaagatgg atttatgagt
    15961 gttactgaga aaacttggga taagcaaatg gatacaaatt tgaaaggtgt ttatttcttt
    16021 acacaggaat ttattaagtt tgttaaagaa aagaatcaaa tgcaagcaaa tattattatg
    16081 atgtcctcag aaagaggctt gtgtggtgat agtattccgt atggattatc aaaggctgca
    16141 attaactctt tagttgtagg cttgtctaag aaatatattt ctgagggaat tagggttaat
    16201 ggtattgctc ctggagtaac tgcaaccgct atgactggta tttctgaaaa gggtaatttg
    16261 tataatcctg caacgatcgg ttatagatat tttctcccag aagaagttgc tcaagttgct
    16321 ttgtttttgg caagtagtct ttcaaactgt atcagtggtg aaatcatagc ctgtgaccag
    16381 gggcaatatt taagtcgaaa ttgggggtaa taacttggga atattattaa aaaaatataa
    16441 tagccttagt gagcctgcaa aagcatctat ttggtttaca ctttgtaatg tgttgcaaaa
    16501 aggaattcta tttttgacta cacctatttt tacaagaatg ctttcaactg cagaatatgg
    16561 taagtatacg atttttatat cgtggtattc tattatagca attttcacaa cgttgaattt
    16621 atctgcaggt gtctataata aaggactaat taaatacgag aataaatatg cattaacctc
    16681 gtcattttta ggattatcgt catttatttc cctttgtgca ttgatgctat accttccatt
    16741 tagaacggtt ataaatgggc tactggattt atcgacggag tttgtcatat tgattcttat
    16801 tgaatcaata tttgagccgg cttttttgct ttggtcagtt aaggaacgat ttgattacaa
    16861 gtatcaaaaa ctagtactca tcacagttct tatggctgtt ttaaatccag gtctcggtat
    16921 tatattaatc ttatcatttg gggagtatgc tatttggaga gtacgagctt atgtcgtggt
    16981 aaatgttgta gtggggatgt ttattggcat aggaatactg gctaagggta agaaattatt
    17041 tgataaagag tactggacat atgcgctcag atttaatttg ccattaatac cacattattt
    17101 atcaatgaca ttgctgaatc aggttgatcg ccttatgata aatagtatgg ttggagctag
    17161 cgaggctgcg atttatagta tcgcttacac tatatctagt atgatgaata tcataacaac
    17221 agctataaac ggttctttta ttccttttac atacaaagca attaaagatg gcgtgtatga
    17281 aaaaattaaa tccgttgcta atcaactatt agtgttgatt tttgtcttgt gttcgtttac
    17341 tatgctgttc gggccagaat tgatttgggt tgtcggagga gaaaaatata tggatgctgt
    17401 ttggattatt cctccagttg cggcatcagt atttttcatg tttttatatc cgctttttgg
    17461 caatattgaa ttttactatg aaaagacaaa ctacgtaatg tttgcatctt gtgtgggctc
    17521 tatcgcaaaa attatttcaa actatgttag tattccccgt tttggatata tttcggctgg
    17581 ttacacgaca ttgatttgct atatgttgtt ttcctttgcc cactacatgt tttataaaaa
    17641 aattcttaga gaaaatggta taaaagaaga tatgtataat attaaaaata ttatatttct
    17701 ttctgtctta atgattgtgt taactattgg tatgacaata ttatactttt ctacaattct
    17761 aagatatagt attattattg gattagttat tgtggctttt cttaaaagga cgcaaataat
    17821 gaaaatcctt aaaaatataa aaaattaaca agcaaatctt gggaatggaa cggaggcacg
    17881 gtgaaatgag attattgatt ccatctgcta agattgtacc ggaagaactt caccatcttg
    17941 gaaaacttcc tgcaattatc tatccgatta atcaaaaaat tgtatttgat tatttatatg
    18001 atcaatataa agatgtatgt tctgctatcg atattgcctg ttacgaaaag atggataagg
    18061 tagcaagacg attagataag tatattaaat ctaaaacagt aaatattatt cagcttaaag
    18121 agttagggga tcttggaaga actatatatg attctctaat aggatgtgac gagcctgtta
    18181 ttattaattt tgctgatacc attatcaatg ataatatata ttccttggaa tgtgacagct
    18241 ttttctatgc tgaagactat tatagtaata cttggacatt ctttgaagaa aaagacggag
    18301 atattatttc tgttttagat aagaacgagt taaaagaaga tgatggaaag aagcacaaac
    18361 tgttttctgg tgtatttcaa attatggatg cccagtattt tagagagtgt ttgcgtaaag
    18421 ctttgatgtc aaatgtagta aatgtgaata gtttttatca agctttacaa gagtatagca
    18481 aacgatatga atttctctct attaaaacaa ataattggtt tgacattgga catgcagata
    18541 aatattataa ttccaaattg gaagttaagg caagagaatt taaccacatt tcaattgata
    18601 aagatcgtag catcctgaga aaaattagtg aagatgttga aaaatttatc ggagaaatta
    18661 agtggtatct taagttgcca gcacaggtag aatatgtgag acctagaata ttcgaatatt
    18721 ctacttcgta tattaatcca tatgtaagta tggaatacta ttcgtatcat actgttcacg
    18781 agttatttct ctatagtgac ttaacaaaaa aacaatggat agatatcttt aatagaatac
    18841 gatttgtatg ctcagacttt aagagatact ctgtttcagg ggataatatt caaaagtcat
    18901 tgaaagatat gtatctcgat aaaacatttc agagattcaa taagctcaga aaggaccccc
    18961 ggttcacaga attcttttct tctgatattc aaataaatgg agtcagatat aaatctttgg
    19021 accagataga agctttattg agcgtaagtg ttccaagaga attgtttgac attacgcaat
    19081 ttaatattat tcatggtgac ttatgctttg ccaatattat ggtagataac acattttcgt
    19141 tcattaaagt catagatccg cgaggtaagt ttggagattt tgatatttat ggtgattata
    19201 gatatgaact ggcaaaattg tttcatagtg ttgatggaaa atatgacttt ataattaagg
    19261 acttgtttac aataaaatat gatccaaaga aggcaatcat agactatatt gttcaagatc
    19321 gtaaacgaga ttatgattta tatgaagtat tttactctgt cttcaaagat gaaataggtt
    19381 ctgatttgaa aaaaattgaa cttattgagg ctttgctgtt tttaagtatg attcctttgc
    19441 atggagaaag cttaaaccat cagatggcta tgttagcaac tggtttggaa attttaggac
    19501 gagttgtccc ggatatttat tgttaatgct ttgagctatt gtttttctat ttgatcagtg
    19561 taaagccggg catataaatt gcctggctaa aataaaggag atgtcttagt tatatgttta
    19621 aagattacgc atttgttttt gatattgatg gaactttgtg ccccatcaaa aagaaagatg
    19681 agaaatatga agatttagtt ccgtatgcta atatggtgga gaagttgcga tactataagg
    19741 agaacggagc aaagattaca ctgttcacat ctcgcaatat gaattcttat catggtaatt
    19801 taggtgtgat caatgcaaat actgcaaaaa tcttgttggc ttggctagat aagtgggaga
    19861 ttccgtatga tgaaattctt tatggaaagc cttggccagg ccataaaggg ttttatgttg
    19921 atgatcgcac agttcgtccg gatgaatttt tatcgtgtac cctggatcag ctcgatgaga
    19981 tttgcaaaaa atccaaattg aaatctgagt aaaggagact ttataaagtg aataagatga
    20041 cggttattat tacaatggct ggtcttggca gtcgctttcg taaagttggc tacactgtgc
    20101 ccaaatttat gattgaagca aaaggtaaaa ccttatttga ttggtcctta gacagcttgc
    20161 ttgattataa ttcacatgta gaaaagtatg tttttgttgt gcgtaaggaa gatgatgcta
    20221 ctgtttttat caaagaacat tgcagtctgt atggaattga aaatgtcgag gtagttgaaa
    20281 ttgactatat gactgatgga caagccacta catgtatgct tgcaattcct tattgcgcac
    20341 ctgataatgc aattatggtt tataacatag atacatatgt tgagccaggt gagatgaaat
    20401 acgttgatat ttctggagaa ggacatattc cgtgtttcca tgcggacggt gatcattgga
    20461 gttttgccaa gttgaacgaa tatggtgatg tagtagaagt aagagaaaaa gttagaattt
    20521 ctaacaattg tactttaggt gcatattatt tttcttctgc aaaattatat gcatcactct
    20581 acgaagaata ttatgcagat gaaaggcatc tggaaaagaa tgagaaatat attgcgccgc
    20641 tatataatta tatgatagag aagggcatga aggtaaccat tagtatagta gataaatcaa
    20701 aagttcacgt actcggtact ccagaagagc tcgatgtgtt cttaaatgaa tagggaaaat
    20761 ataatcatag aaaatgttaa ttataaagct gcgtgtgtgg gggagtacta ttcgatagat
    20821 attctaaaaa tactaatggc tattttagtt gttgttcgtc atttaggtca aaactattta
    20881 gctccagatt aagcatttag tattggtatt gttgcaggac tgagtacggt tgccgttcct
    20941 acttttttca tcatcagttc ctttttgttg tgtagtggtg aagttacatc cgctaaatta
    21001 tctaaacaaa tctacagagt acttaaaatt tacattattt ggtctatatt atatattcca
    21061 ttagtattaa agaattgggt acagtcagat tttagctgga aaacagatgt attattgtat
    21121 atcagagatt ttctgtttat tggtagttac tatcacctgt ggttcttgcc tgcactggct
    21181 tttgctctat ggttagtacg caaaagccag gtttctaaaa taaagtttct cagtggtttg
    21241 ttgctatgcg tagtaggttt agcatttgaa tcttattggt ttatattatc tgggaatgat
    21301 tccatcgagt atattagata ttgttataaa agcgtgtttg taacaactcg taatggatta
    21361 tttataggtg taccatgcgt cattattggg caacacttag ccttccacaa aaacactata
    21421 cttaataagg tctttaaata ccgtaatttt atcttatgtg ctgttttagc tataggatgc
    21481 ttattagttg gtgaaagttt catcataaat caaatagctt tgcgagaagt caataatttg
    21541 ttaatatttt ccattccatt agcactggta gttgtatcag tatcactgag cctaaagata
    21601 gtacatttat aaaaataaca gtacatctgc gaagaattag tacgttatta ttttgtttac
    21661 atccgtatat aatagctgct ttaaatttta ttttcccaaa attggggatt acaaattcat
    21721 taatagaaat gacttgtgga atgataataa ttttaatttc tacagttttt gtgtatgcgt
    21781 gtagtgtgaa atttaccttg ctgaaaaaat tatattagat tagtaactgg tacatgtaaa
    21841 tttgttgaaa ttatagcagc atagagatag gaattctgtt gagttttatt ttcgctggcc
    21901 gaggttattc atgttagagt gggtacctcc ttttacgaaa ccttcttgat ggtactcatt
    21961 tagcgcatga tgaaaggaga gtttatgaag aaaatcatat cttctatttt ggttaatgtg
    22021 ttatctgcat tgtatcaaat atttgggttt cgattttaat tgcagttttg gctatgtttt
    22081 tatacttgtt tgcgatggct gaggagaaat caggattagg tttgaaaaaa tcttttcttg
    22141 tctggattcg gtatttcaga aaatcaagct catttagaaa aatgtttttg cttgtgtttt
    22201 ttacaaatat gattcttttt agaacactga tggatagata tgtttggcta aatcctttgt
    22261 ctaatgtgtt tggtagttgg tggatttact ctgtgaatga aacgacaggg gagattagat
    22321 taactacaga atgttttgaa aatgttattc tgtttattcc atttataatt ctagtaatgt
    22381 ggtataaggc ttcagaaaaa gattttggaa aaatttatca gagattataa aatttgtttt
    22441 tttatgttcg tgtcttatag agtttttgca gttattttta cacatagaga cattccaatt
    22501 gtcagattta ttttataata ctttgggtgg cggcattagt ggggttatat attatttgag
    22561 ctgatatatt catcctaacc ttaaaaataa atgagcagaa ttttaaaaga ttggagagat
    22621 tctatggatc ataatgcaaa ttattatcat tggcttacaa atgccaatgc agaaattgta
    22681 gaggaactgc ggtcatattc cgagaaggac attgaggact ccttctataa aaatctgtcc
    22741 tttggtaccg gtggtctgcg tggcaccatt ggtgcaggca ctaatcgtat gaacgtacac
    22801 accgtaggta aggcaagcca gggactgtca gactatctga ataagaccta tgaaacccct
    22861 tctgtcgtcg tgggctatga ttcccgaatc aagtccgatg tatttgcaaa ggttgccgcg
    22921 gacatctttg ctgcaaacgg tattcaggtg catctgtggc cggagctgct gcctgtgcct
    22981 accgtatcct ttgctatccg ttatctgaag gcttctgccg gtgttatgat caccgcatcc
    23041 cataatcctt ccaagtataa cggatataag gtctatggcg caggcggctg ccagatcacc
    23101 accgaggctg ccgctgagat tctggctgaa attgaaaagc tggatatttt tgcagatgtg
    23161 aaaatgggcg gcgacgcttc cagaatcgct tctatccagc cagaggttct gactgctttc
    23221 attgaagaag taaagggcca gtcggttctg tttggcgaag aagtggacaa gaatgttgct
    23281 atcgtgtatt ctcctttgaa tggtaccggt ctggtgcctg ttacccgtac tctggcagaa
    23341 atgggctaca gcaatgtgac cgttgtcgaa gagcagcgtc tgccagacgg taatttcccg
    23401 acctgtcctt atccgaatcc ggaaattaat gaagctatgt ctctgggcat ggagtatgcc
    23461 aagaagtata atgctgatct gctgctagct accgaccctg actgcgaccg tgtgggtatc
    23521 gccgtgaaga atgcagaagg ggattatgtc ctgctgtccg gtaacgaaac tggtctgttg
    23581 cttctggact acatatgctc tcagagaatt aagcacggca agatgcccac tgaccctgtg
    23641 atggtcaaga ccatcgtgac tatggatctg ggcgagcgga tcgcttccaa ctatggcgtg
    23701 cgtactgtcg atgtgttgac cggcttcaag ttcatcggcg aacagattgg tatgctggaa
    23761 aaggcaggca aggtggacag ctatattttc ggctttgagg aatcctacgg ctatctatcc
    23821 ggcagctatg tccgtgacaa ggatggtgtc aacgccgctt atctgatctg cgagatgttc
    23881 tcttactaca agactcaggg tatcagtctg tttgataagc tgaacgagat ttatgctaag
    23941 tatggctact gtttgaacac cctgcattcc tttgagtttg agggtgcggc aggttttacc
    24001 aagatgcaga aaattatggt tgaattccat aaaggtcttg atatgattgg aggtaagaag
    24061 gtcattgaaa ccttggatta cagcacggga ctgaatggcc tgccgaagtc tgatgttctc
    24121 aaatatctgc tggagggcaa ctgctctgta gtggttcggc cttccggcac tgagccgaag
    24181 ctgaagacct atatcagcgt tagcgcagaa agcaaggaag ctgccgaagt aatggaagct
    24241 gttatggctg ctgaactggc tgaaatgttt aagtaatact atgaaaaaga tctgagtgtc
    24301 aatgtccgaa gtagcaacat ctatgtttaa taaaaatttc ctgctttacg gttctgttta
    24361 cataattgag gtaaaggggc cgactgtgtg gatcgaaaag gcaaagaagt gttaacagag
    24421 acacagcagc ctgatgaagc accgatcaaa gcagtaaggg agaaataaga gatattagag
    24481 ttttaataat gtattcagca atagagatga aaggagtaga atatgaataa aactattgaa
    24541 ataataaaat gagggggaaa gaaataaacg tgatattatt agttttgaga aggcgttttc
    24601 aatattcgct attgtattga tgtactattt tcagcaatcg tatttgccag caatactgaa
    24661 caaagcaata tctattggtg atacaggagt gcatatattc ttcttttgct caggttttgg
    24721 gctatatctg tcatatttaa aaaagcctat tacattgggt gaatttttac agaaacgatt
    24781 tatcaagatt tatattccgt atattatcgt aattacggta tcagtgttac taccttatat
    24841 gacacaagat ttaaatgctg caaaagtata tttgtctcat gttttgttat ttaaaatttt
    24901 tctaccagta tatgaggagt cactgggtcc ctttggttta tttcgacaat tattcagttc
    24961 tatttcttat tcataccaat tgtaaaacta tagagaaaaa taggaatgaa atgattgctt
    25021 gttgcaagct gagttattag tatctgggct attatgatgt ttcatacagg atatggaagc
    25081 atacgagttc ttgggagctg ctttgcgcaa tatatttggg aatttacttt cggcatgttt
    25141 ggttgcagag tatttagtga aaagaaaaat agtaagattt aataatatat tcgtgattat
    25201 ggcgtccatt gttggaattg gttttgctgg tatatcgaaa attattggtg gactgatgga
    25261 gtctattaat gatatttttg cattcttcgg ttacggtgca attgcaattt taatgtatca
    25321 agttattcca tttagaaaga taatgcctag gatttcaaga tactcatatg atatatatct
    25381 actccatatt cttgtattta gtacgattca tcaaattatc cctaacttgg ttttggcggc
    25441 atttgtttcc attcctataa cgttggtgtt gtcatattat tatagtatta tgttatatag
    25501 acttaaatta aaatgatagc ataattgtcg cctctaccgg gcggttgcca tcctgattaa
    25561 cagcctccac gcggcggatg gtgggcactt aggtagttcg taacctagtg gtagatggtt
    25621 ggtaaaaagg agataaaact aaatgatt
//
LOCUS       DAFBVQ010000040        23734 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.041, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000040 DAFBVQ010000000
VERSION     DAFBVQ010000040.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.041"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            257..532
                     /locus_tag="LLC22_001786"
     CDS             257..532
                     /locus_tag="LLC22_001786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435064.1"
                     /translation="MRESFEQQKKLLHDRYGALSMDDRRQILCKLRKRNILMYRQLER
                     LKHDLLRLESKRVQCELEGNQTQVEVVETKILKKKEQFLKMLTQNKK"
     gene            545..2623
                     /locus_tag="LLC22_001787"
     CDS             545..2623
                     /locus_tag="LLC22_001787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sodium:proton antiporter"
                     /protein_id="HBK5435065.1"
                     /translation="MEFAELVIVFAVTITLSNIASRILPMIPAPLIQIFLGVVLGLTE
                     WGQSIDFEPELFLVMIIAPLLFREGEKADISSILKNFGTILFLAFGGVILTLVGVGAT
                     LSFLLPSVPLAACFAFGAALGPTDAVAVSSLSGRVNIPKKAMHILEGEGLLNDASGVT
                     AFQFALGALITGSFSAVNAGMSLVVSSIGGALIGFLLVWFKQKIIHLIEKASAQDVTG
                     YLLIELLLPFLAYVLAEAFDVSGIIAAVAAGILQASGFRKISVFDAELSSLSHSTWTT
                     IAFTLNALVFIFLGIELTQVFSPVWGDGLYPNGLLLAIIVLISVMLFVIRFISISLFY
                     VFKDGSKKFKKQLNEILILTFGGVKGTVSLATIFILPFSINNMMFYQRSLLLFLTAGV
                     ILVTLVIGIIVLPMLTETEEAKSTDLNALMILEEVVEVLRKEIKEIDRNTKEFLATEA
                     VIENYQERIRDLYLEDLTDDEKQEVQEIQALILSIERDGLDESYRSGKLSSNGYRFYS
                     RFLSRFEHSITSQILSFIGFWFIVVRRLMRIVLHPKMFWQRRYADRQTFISDEDIQEI
                     RETYQKNTQLIIESLDNLTDIYDETMVQFFIQQRKLEGIKMNSGNLISSWMIQQDSLF
                     TKKMLRGYYLERKIIDEYEVAEKITTFSANSYRRNINLLESYTMNKPSDNFSFRFAFR
                     AKSKKTSPIK"
     gene            2783..4669
                     /locus_tag="LLC22_001788"
     CDS             2783..4669
                     /locus_tag="LLC22_001788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5435066.1"
                     /translation="MLKELKVTDLKKTYGEKDLFDQISFLVHEKDRIGLIGTNGTGKT
                     SLLNIIAGIDSSDGDRQTVFYPTDYRIGYLSQAAEFSDELTVLQAVFQGNSPLIQTVR
                     AYEEALIELGENGEDPDVQKRYAKAEEQMNKEDAWTTDTNAKIILQKLGISELDKKIS
                     TLSGGQKKRVSLAQVLIDEPDLLLLDEPTNHLDYEAIEWLENYLKQYRGALLMVTHDR
                     YFLDRVANRIFELSFGKLYEYKGNYEAYVLEKAERDRVEVEQEEKRKRLYKQELAWMR
                     AGVQARGTKQQARINRFEDLKENLYQVNQEDDLELNLATQRLGKKVLEIKDGSYRIND
                     QTLLEHLDLLIQSRERLGITGKNGAGKSTLLNILAGRIPLDSGTMSIGETVHLAYYTQ
                     ENEEMAPDKRMIAYLQEAAEEAKTADGSQIGVAELLERFLFPRFMHGTLIGKLSGGEK
                     RRLFLLKLLIQQPNVLLLDEPTNDLDIATLTILEDYFRSFPGAVITVSHDRYFLDKVA
                     DKLLVFQGNGKQELYYGNMSSYLLKQKETQQPAEKAKPKIQSKEPAEKKKLSYMEQKE
                     WETIEDEIAELEEKISLLQEEMNHQGDNFTRLQELQNDVSETEAQLEEKMARWEYLSE
                     WVED"
     gene            4681..5628
                     /locus_tag="LLC22_001789"
     CDS             4681..5628
                     /locus_tag="LLC22_001789"
                     /EC_number="2.1.1.45"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thymidylate synthase"
                     /protein_id="HBK5435067.1"
                     /translation="MEQAYLDLGRKLLEEGHRKEDRTGTGTLSLFGYQMRFDLQKGFP
                     LLTTKRVPFGLIKSELLWFLKGDTNIRYLLQNKNHIWDEWAFERYIKSPDYNGPDMTD
                     FGHRCLTDPEFNEEYKKQSKLFCEKILTDDSFAETYGDLGHIYGYQWRHWETKDGGFI
                     DQIKQVIEAIKKTPDSRRLIVSAWNPEDVPSMALPPCHTMFQFYVQEGRLSCQLYQRS
                     GDVFLGVPFNIASYALLTHLIAHETGLAVGEFVHTLGDAHLYINHIEQMKEQLSREIR
                     AFPTLVLNQEKQSVFDFEMEDIQLEGYDPHPAIKAPIAV"
     gene            5648..6175
                     /locus_tag="LLC22_001790"
     CDS             5648..6175
                     /locus_tag="LLC22_001790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5435068.1"
                     /translation="MLAAIWAQDENGLIGKEDRLPWRLPNDLKFFKQMTEANTLVMGR
                     KTFEGMGSRPLPNRQTIVLTRDSSYKAEGVHVMHSVEDVLALEKETDGIFFIAGGSAV
                     YQEFLPFCTILYRTVIHHVFDGDAYFPPVDWSDWSLINTSQGEMDEKNRYPHQFETYQ
                     RNENPVKSGTGELTI"
     gene            complement(6238..6891)
                     /locus_tag="LLC22_001791"
     CDS             complement(6238..6891)
                     /locus_tag="LLC22_001791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hemolysin III family protein"
                     /protein_id="HBK5435069.1"
                     /translation="MEKTKFNRTYEILNEVFNAVTHGIGTGLSIAGLVVLLVKGAHLH
                     SSLHIVSYAIYGSMMILLFLTSTLFHSLIFTKAKKVFQVFDHSSIFLLIAGSYTPFCL
                     LSIRGWLGWTLFVLIWLFAILGIIYKALTLHKRERVSKVSTIIYIFMGWLCVVAAVPL
                     YHSLGMTGVILMVAGGLSYTIGAFFYSLNSIRYMHVVWHLFVMLGAGFMYFSVLFFT"
     gene            7023..7865
                     /locus_tag="LLC22_001792"
     CDS             7023..7865
                     /locus_tag="LLC22_001792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5435070.1"
                     /translation="MTNVKIVTDSSCTMEKNVRDALGIRVMPLSIMIDGTVYPDDDQL
                     DGERFMEMMAKAKNLPKTSQPPIGEFISMYDELGEDGSEVISIHMTKGLSGTVEAARQ
                     ASNLTKTKVTVIDSDTTDQGLSFQVIRAAELAKEGKTVEKILEEVKKVQDNTKLYIGI
                     STLDNLVKGGRISRTTGLLSSVLNIRVVMNFAHSELIPVTKGRGKKTFDKWFNNLKNE
                     LKELPNVRQIGISHADAKELAQEFKEGLQELFPDMHIPVLHTNPVIATHTGKDAFAIM
                     YYVD"
     gene            8023..8919
                     /locus_tag="LLC22_001793"
     CDS             8023..8919
                     /locus_tag="LLC22_001793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294417.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBK5435071.1"
                     /translation="MKLTKRHLILVLFPLLIAIIIYAGLAASIPKAGPLMKPVTTVRE
                     DPNKKEKLHYIAIGDSLTEGVGDQTKQGGFVPLVANDLKDRYNLTAVETENYGVNGER
                     SDQILKRVKTKEEIRNNIKTADFITLTVGGNDLMKVIQNNLFGLTVNSFKKPLKNYQE
                     NVTELLEEFRSLNKTAPIYILGIYNPFYLNFPEITDMQTIVNNWNKGTETVTKKMPNC
                     YFIPINDLLYQGLNQEVGVTEEGTDQTTSTTENLNGIKNNVLYEEDHFHPNNLGYQLM
                     ANAVRDQLIETQNQWLEKEDDQ"
     gene            8922..9635
                     /locus_tag="LLC22_001794"
     CDS             8922..9635
                     /locus_tag="LLC22_001794"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288396.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpmS family protein"
                     /protein_id="HBK5435072.1"
                     /translation="MKTRSDVSSNKTKKTNYWKFAFLILLGVVLGSTVFLGSRIFANR
                     EPELPEIPALTERQGDPVLTINSNKEKVNQIISFFLSEYQKDSDIEYKFYLENEALLN
                     GTFEVLGFPIDFYLYFDPYVMENGNVQLKARSLSIGTLSLPIKDVMNMIKRNYKLPDW
                     IEVNTDDLTIMLRLDQFRMQNGMYIKADKIDLVNDDIRFSLYLPKDTSDASNNSNTNK
                     TSTSSTESKTKENKKSSDE"
     gene            9655..10173
                     /gene="msrA"
                     /locus_tag="LLC22_001795"
     CDS             9655..10173
                     /gene="msrA"
                     /locus_tag="LLC22_001795"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309572.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5435073.1"
                     /translation="MERAIFAGGCFWCMIQPFDTLPGIHTVMSGYTGGHVPDPTYEQV
                     KSQTTGHTEAVEIIYDPTLISYEQLVELYWQQTDPTDAFGQFEDRGDNYRPVIFYLTE
                     EQRIIAEKSKKQLAESGRFEQPIVTKIEPAQPFYLAEEDHQEYYKKHPENFKRNHARR
                     AAFIEENWRNEG"
     gene            10170..10397
                     /locus_tag="LLC22_001796"
     CDS             10170..10397
                     /locus_tag="LLC22_001796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300423.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YozE family protein"
                     /protein_id="HBK5435074.1"
                     /translation="MNRSFFHYLMTLRGGGTHDALSVFATEAGKDIQFPKHSSSYEEI
                     SNYLELNVDYLPSMDIFDEAWEKYLENNHDI"
     gene            10549..11100
                     /gene="lepB"
                     /locus_tag="LLC22_001797"
     CDS             10549..11100
                     /gene="lepB"
                     /locus_tag="LLC22_001797"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313873.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK5435075.1"
                     /translation="MTKKQRYINRFWLVFKYLLVSVFLAFMLRGFLFIPVPVEGNSME
                     NVLKQGDMVVMEKFSEIRRFDIVVFQLADGTIYIKRVIGLPGENVSYQNDQLKINGKV
                     VKEPYLTKNLKSDHANASYTTDFTLQELTGQSKLPEDNYFVLGDNRRVSKDSRSFGTI
                     NKTDILGKARFVYYPLDEIKWIQ"
     gene            complement(11183..11683)
                     /locus_tag="LLC22_001798"
     CDS             complement(11183..11683)
                     /locus_tag="LLC22_001798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="folate family ECF transporter S component"
                     /protein_id="HBK5435076.1"
                     /translation="MNARLLSTSALLLALDVILYKIAIGPAYFQITFGFLSMALMGYL
                     YGPIWAGLLEMLSNTLNFTIFGSGTFQAAFLITAFLGGFINGLFLYHKKINLPSVIAA
                     QLLIMIPVSLFINSWLMSVLFGADFKVIFLGRFIRNMIQIPIQIMVVYSFIKTLEARK
                     VFKRAV"
     gene            complement(11962..12360)
                     /locus_tag="LLC22_001799"
     CDS             complement(11962..12360)
                     /locus_tag="LLC22_001799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5435077.1"
                     /translation="MNSMVFVNFPVADVNRSVAFYEKLGFKKNEEFSTEEAGSMVWDD
                     TFWIMLLSHDFYKKFIKDKEIADNKKTSGALISFSVENADEVKKFAQIAKENGGTFHE
                     VDMGMPEEEMFSLEVQDLDGNTLEPVWMKM"
     gene            12620..13480
                     /gene="ylqF"
                     /locus_tag="LLC22_001800"
     CDS             12620..13480
                     /gene="ylqF"
                     /locus_tag="LLC22_001800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YlqF"
                     /protein_id="HBK5435078.1"
                     /translation="MTIQWFPGHMAKARREVSEKMKYVDIVFELVDARLPLSSRNPML
                     DQIIQQKPRLVLLNKADLADPQQTKLWQEYFRKQGHLALAITAQESKGIKGLVPAAKE
                     ALKEKRARDAARGIKPRAIRAMVLGIPNVGKSTLMNRLVGKKIAQTGNKPGVTKGQQW
                     LRLGNELELLDTPGILWPKFEDEEIGKKLALTGAIKDQLVHLDDLAIYGLDFFARYYS
                     GRISDRYGLSIEQEEKLAPELLMDITAKRGYKEDYDRGSELVVHDIRQGKLGRYTLDR
                     CEEMEQKSDD"
     gene            13473..14240
                     /locus_tag="LLC22_001801"
     CDS             13473..14240
                     /locus_tag="LLC22_001801"
                     /EC_number="3.1.26.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264725.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease HII"
                     /protein_id="HBK5435079.1"
                     /translation="MTESIQSIKERLKSIQRIDDPTLESLRNDPRKGVQQALASFERR
                     LKKEALIKEKYEEMFCFEKQGYAQGHQWIAGIDEVGRGPLAGPVVAAAVILPKNEIIL
                     GLNDSKQLSEKKRELLYQQVQEKALAIGIGIVDQQTIDDVNIYEASKLAMIQAVEKLS
                     IVPSYLLIDAMTLDLPIQQEKIIKGDARSVSIAAASIIAKVYRDQLMKEYDVLYPGYG
                     FSHNAGYGTKEHLEGLERQGITPIHRKSFAPVKKYLQ"
     gene            14296..15153
                     /gene="dprA"
                     /locus_tag="LLC22_001802"
     CDS             14296..15153
                     /gene="dprA"
                     /locus_tag="LLC22_001802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309564.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-protecting protein DprA"
                     /protein_id="HBK5435080.1"
                     /translation="MYQIEENLLKLAYTKGISSQGKWALANWMMQYPYKEIGFEDIIK
                     IGKITKHRELFRKSWQEIHANWGKIQSKQSFITCFDPKYPPQLLHLTYPPIVLFYNGD
                     LSLLSCNMLSVVGGRHTSALAKKTVYYLLKPVIEAGYVIVSGCAKGIDTYGHQAAISH
                     GGRTIAVIGTGIEQVYPAENRDLQEVIANDHLLLSEYPPQSGPKKHCFPMRNRIIAAL
                     SKGTCVFEAKKKSGSLITAQQALDLGRTVFSVPGNILTEHSTGCHHLIQDGAVCTVSG
                     EDILAEFKE"
     gene            15275..17353
                     /gene="topA"
                     /locus_tag="LLC22_001803"
     CDS             15275..17353
                     /gene="topA"
                     /locus_tag="LLC22_001803"
                     /EC_number="5.6.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002380330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I DNA topoisomerase"
                     /protein_id="HBK5435081.1"
                     /translation="MAYKYLVIVESPAKAKTIEKYLGRNYKVMASVGHIRDLPKSKMG
                     IDFENNYEPHYISIRGKGDVIKSLKAAAKKAQKVYLASDPDREGEAIAWHLAYLLGLD
                     LKEKNRVVFNEITKDAVKAAFKEPRTIDVDLVDAQQARRTLDRIVGYSISPILWRKVK
                     KGLSAGRVQSVALKIIIDREKEIREFVPEEYWSIDGNFKKARKKFKANFWGIDGKKKK
                     LPDAQSVKEVTARIDGTDFEVKKVEKKERKRNPANPFTTSSLQQEAARKLNFRTRKTM
                     MVAQQLYEGITLGKQGTVGLITYMRTDSTRIADTAKAEAAAFIEDTYGKEFSRHDHRK
                     IKNAQGAQDAHEAVRPTSVLRTPDELKQYLDKDQLKLYTLIWSRFVASQMTPAILDTM
                     KVTLEQNGVIFIANGSKIKFKGFMQVYVEGRDDGKEEKENILPELEEGDVVQSVDIEP
                     KQHFTQPPARFSEATLIRALEENGVGRPSTYAPTLDTIQRRYYVKLTQKRFEPTELGE
                     IVNSLICEFFPQIVDIHFTAEMEGDLDKIEEGTEAWVKVVDRFYKPFEKELTNAEEKI
                     EKIQIKDEPAGFDCDVCGHPMVIKLGKYGKFYACSNFPDCRNTKPIVKEIGVTCPVCH
                     EGQVIERKSKKNRLFYGCSRFPECEFTSWDKPVGRNCPKCDGYLVEKKVKGGKQVVCV
                     NGDYEEDIQK"
     gene            17322..18698
                     /gene="trmFO"
                     /locus_tag="LLC22_001804"
     CDS             17322..18698
                     /gene="trmFO"
                     /locus_tag="LLC22_001804"
                     /EC_number="2.1.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FADH(2)-oxidizing
                     methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))-
                     methyltransferase TrmFO"
                     /protein_id="HBK5435082.1"
                     /translation="MEITKKTSKNNRKEVLSLKMVNVVGAGLAGSEAAWQIAQAGVPV
                     RLYEMRPVKSTEAHHTSNFAELVCSNSLRGNSLANAVGLLKEEMRRLNSVVITSADET
                     AVPAGGALAVDRDSFSETITRKVKEHPLVTVINEEITEIPEGITVVATGPLTSHPLAE
                     SIKAFNGSDGFYFYDAAAPIVDKATIDMDKVYLKSRYDKGEAAYLNCPMTEEEFKAFH
                     EALINAEVAELKSFEKEKYFEGCMPIEVMGQRGFKTMLFGPMKPVGLEDPKTGKRPYA
                     VIQLRQDNAAASLYNIVGFQTHLKWGEQKRVFRMIPGLENAEFVRYGVMHRNSFMNSP
                     ELLKPTYQSTKREDLFFAGQMTGVEGYVESAASGLLAGINAARLAKEMEPVEFPQETA
                     IGSMAYYITHAEGKHFQPMNANYGLFPELPERIRDKKARYEAIAQRALKANEAIKTEL
                     EKTAIPNE"
     gene            18896..19801
                     /gene="xerC"
                     /locus_tag="LLC22_001805"
     CDS             18896..19801
                     /gene="xerC"
                     /locus_tag="LLC22_001805"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerC"
                     /protein_id="HBK5435083.1"
                     /translation="MTEATWEQKFLRYLIVERGYSEKTKEAYEEDILHFKHFLEESGD
                     ADLLKAEYFTVRVYLSALADHRPSYSRNSISRKIASLRSFYQYLLKEEVIKENPFSYV
                     HLKKKNLRLPRFFYENEMQALFDSVAGDSPLDLRNRALLEVLYGSGIRLSECSSLSVS
                     DIDFDSEVMLIHGKGNKERYAPLGSFAQDALQEYFREGRQVLMTKYHEEHDIVFVNHH
                     GKPITPTGIEYVLNQMIKKSSLDSDIHPHMLRHTFATHLLNNGADLRTVQELLGHANL
                     STTQIYAHVTKESLQKNYRSFHPRA"
     gene            19838..20386
                     /gene="hslV"
                     /locus_tag="LLC22_001806"
     CDS             19838..20386
                     /gene="hslV"
                     /locus_tag="LLC22_001806"
                     /EC_number="3.4.25.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002357489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HslU--HslV peptidase proteolytic subunit"
                     /protein_id="HBK5435084.1"
                     /translation="MVESPFHSTTICAVEKDGKFAMAGDGQVTMGESVVMKGTAKKVR
                     RIYNGEVVVGFAGSVADAFTLEEKFEGKLNEYNGNLQRAAVELAQEWRTQQSMQKLEA
                     MLIVMNDKEMLLVSGTGEVITPDDGILAIGSGGNFALAAARAMKNYAQNDMSAKEIAE
                     NALNIAADICIFTNHNIIVEEL"
     gene            20400..21800
                     /gene="hslU"
                     /locus_tag="LLC22_001807"
     CDS             20400..21800
                     /gene="hslU"
                     /locus_tag="LLC22_001807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002409948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent protease ATPase subunit HslU"
                     /protein_id="HBK5435085.1"
                     /translation="MYELKQTPRQIVSELDEYIVGQHAAKKSVAVALRNRYRRLQLDE
                     KMQQDITPKNMLMIGPTGVGKTEIARRLAKIVNAPFVKVEATKFTEVGYVGRDVESMV
                     RDLVENAIQIVEKEQYSRVYTSAKKNAEKRLVKILVPGIKKEQKQSTNQFEQMMNLFN
                     ASQQNTAEPQEEVTEDIRINRRTVLEQLQKGLLDSREVTIEVEDQKKPAPMMNNGLEQ
                     MGIDLNETLGALTPKKKVERTVTVKEALELLIKEESAKLVKDADIHSEAIKLAEESGI
                     IFIDEIDKITSKSQQSGEVSREGVQRDILPIVEGSQVNTKYGIIQTDHVLFIASGAFH
                     LSKPSDLIPELQGRFPIRVELDDLTAEDFVKILTEPNNALVKQYVALIGTENVSVTFT
                     KEAIERIAQIAFDVNRDTDNIGARRLHTILEKLLEDLLFEAPDMQMGEITITEAYVDD
                     KLGSIAANEDLSRYIL"
     gene            21818..22609
                     /gene="codY"
                     /locus_tag="LLC22_001808"
     CDS             21818..22609
                     /gene="codY"
                     /locus_tag="LLC22_001808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTP-sensing pleiotropic transcriptional
                     regulator CodY"
                     /protein_id="HBK5435086.1"
                     /translation="MTDLLTKTRKINTLLQQKNTFDMQADLPYDKMAVTLGGILDSNT
                     YIIGSDGVLLGYNERHDVNNERIKTMFVEKQFPESYTDTVAQLMKTEANIPITSDITA
                     FPVESREKYPFGLTTVVPIFGAGERLGTIILSRMEQSFADDDLVLAEYGATVVGMQIL
                     YQKSRSIEADVRSATAVQMAINTLSYSELKAVQAIFEALDGDEGRLTASNIADSIGIT
                     RSVIVNALRKLESAGIIESRSLGMKGTYLKVLNSRFKDELAKHSY"
     gene            22691..23566
                     /locus_tag="LLC22_001809"
     CDS             22691..23566
                     /locus_tag="LLC22_001809"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBK5435087.1"
                     /translation="MTVIIQNDQLIAEIAEHGAELISLKSKEHGLEYIWQGDPAYWGR
                     HAPVLFPFVGRLKDDQYVYQGKTYQMGQHGFARDMDFEVIEHGQEMASFILRSTPETL
                     EKYPFDFELVISYELGGDGITVHYQVANTGEKEMFFSIGGHPAFNVPLEEGLSFEDFY
                     LAFSPLKSRLRLPLKGPFIDMDQKTLGQTNTNLALNRELFEQDALVFETRGLNAYAIR
                     SEKSSHSVTLSYKDMPYVGIWSPYPKEAPFVCIEPWCGIADTVNSSGNLMEKVGINQL
                     GAHEIFKTKYSITVK"
BASE COUNT         8215 a         4092 c         5001 g         6426 t
ORIGIN      
        1 tttttgtcgc agccccattt ttttgttgtg ataaaagaac aagaaaggca ggaatgggaa
       61 agtaaacatc cttttgtcag aaacttttat ctttcttaag ttttacttga tatctgatac
      121 tatttggaat agaatgaggc gttgaaaaat ttatggaaat ttctaactag caataaacga
      181 tgaaacaatg aaatattttt catccaaaaa gaactttgct ataatgatgg aagtttgtgt
      241 ataggagatc tggaaaatga gagagagttt tgaacaacaa aaaaaactgt tgcatgatcg
      301 ctatggcgcc ctttcgatgg atgaccgccg tcaaatactt tgtaagttgc gtaaaagaaa
      361 tatattgatg tatcgtcagt tggaacgtct gaaacatgat ctgcttcgtt tggagtcaaa
      421 acgtgtacag tgtgaattag aggggaacca aacacaggtt gaagtagtcg aaaccaaaat
      481 tttaaagaaa aaagaacaat ttttaaaaat gcttacacaa aataaaaaat aaaggggatg
      541 gacgatggaa tttgctgagt tagttattgt atttgcagta acgatcacct tatcgaacat
      601 agctagccgc attttgccaa tgattccagc tccactgatc caaattttcc ttggagtggt
      661 attaggtctg acagagtggg gacaatcaat cgattttgaa cctgaattgt tcttagttat
      721 gattattgca ccattgttat ttagagaagg agaaaaagca gatatttctt cgattctcaa
      781 aaatttcggg acaattttgt tcttggcatt tggaggagtc attttgaccc ttgtcggggt
      841 aggtgcgacg ttatcattcc tgttgccaag tgtcccactt gctgcctgct ttgcttttgg
      901 agcagcgtta ggtccgacag atgcggtagc agtcagttct ctttctggac gagtgaatat
      961 ccctaaaaag gcgatgcata ttttggaagg agaaggtctt ttgaatgatg catctggtgt
     1021 tactgccttc cagtttgctc ttggtgcgct gatcaccgga tctttttcag cagtaaacgc
     1081 ggggatgagt ctagtagttt ctagtattgg gggagctttg atcggctttt tgcttgtctg
     1141 gttcaaacaa aaaataattc atttgatcga aaaagcatca gcacaagatg tcacagggta
     1201 tctgctgatc gaacttttgc ttccttttct agcctatgta ttggcagagg catttgatgt
     1261 atctggaatc attgctgcag tggcagcagg tattctccaa gcttctggtt ttaggaaaat
     1321 ctctgtgttt gatgcagaat tgtcgagctt gtcccacagt acatggacaa ctattgcttt
     1381 tacactgaat gcattagtat ttatattttt aggaatcgaa ttgacgcaag tgttctcgcc
     1441 agtatgggga gacggtttat atccaaacgg tcttttatta gcgattatcg tattaatctc
     1501 tgtcatgctt tttgtgatca gattcatttc tatcagtctt ttttatgtat tcaaagatgg
     1561 cagtaaaaag ttcaaaaaac agttgaacga gatcttgatc ttaacatttg gcggtgtaaa
     1621 gggaacagtc agtttggcta cgatttttat tttgccattt tcaatcaata atatgatgtt
     1681 ttaccagcgg tctttgcttt tgtttctgac ggcgggtgtc atcttagtga ctttggtcat
     1741 agggatcatt gtcttgccta tgctgacgga aacagaggaa gcgaaaagca cggatttgaa
     1801 tgctttgatg attttagaag aggtcgttga agttttgcga aaagaaataa aggaaattga
     1861 tcgtaataca aaagaatttt tagccactga agcagtgata gaaaattatc aagaacggat
     1921 acgtgatctg tacttggaag atttaaccga tgatgaaaag caagaagtac aagaaataca
     1981 agcactgatt ttgtcgatcg aacgggatgg attggatgaa agttatcgtt cgggcaagct
     2041 ttcttctaat ggttatcgtt tttactcccg ttttctttct cgattcgaac attctatcac
     2101 aagccagatt ttgtctttta tcggcttttg gttcattgtt gtccgtaggt taatgcgaat
     2161 cgttctccat ccgaaaatgt tttggcaaag aagatatgct gatcgtcaga catttattag
     2221 tgatgaagat atccaagaaa tcagagagac atatcaaaaa aatactcagt tgattattga
     2281 aagtttagat aacttgactg atatttatga tgaaacgatg gttcaatttt ttatccagca
     2341 acgcaaactt gaaggaataa aaatgaactc ggggaatttg atttcttcgt ggatgatcca
     2401 gcaagatagt ctgtttacga aaaaaatgct aagaggttat tatcttgaaa gaaaaatcat
     2461 tgatgaatac gaagttgctg aaaaaatcac gacgttttct gcgaacagct atcgcaggaa
     2521 tatcaatttg ttagaatctt atacgatgaa caaaccatct gataactttt ctttccgatt
     2581 tgcgtttcga gcaaagtcaa aaaaaacgag tccaataaaa taaaaaggta aaaattttca
     2641 agttttataa aaaacaaaac atatcagaac aggatcgaat cggtcctgtt ctttttttga
     2701 gaacacaaaa agaacaaata ccaaaaaaat tttcctgaag ttcactattt ttatgataca
     2761 atatccaaga taaggaggga acatgttgaa agaattaaaa gtaactgacc tcaaaaaaac
     2821 ttatggtgaa aaagatttgt ttgaccagat ttcttttttg gtccacgaaa aagaccgtat
     2881 cgggttgatt gggacgaacg ggacgggtaa aacaagtctc ttaaatatta ttgccggtat
     2941 cgatagcagc gacggtgatc ggcaaacagt gttttatcca actgattacc gtattggtta
     3001 tctttctcaa gcagctgaat tttccgatga attaactgtt ctccaagcag tctttcaagg
     3061 aaacagcccc ttgatccaaa ctgttcgagc atatgaggaa gcattgatcg aactagggga
     3121 aaacggagaa gaccctgatg tgcaaaaacg ttatgctaaa gcagaagaac aaatgaataa
     3181 agaagatgct tggactacag ataccaacgc aaagattatt ttgcaaaaat taggaatcag
     3241 tgaattagat aaaaaaatca gtactttatc aggtggtcag aaaaaacgag ttagtctggc
     3301 gcaagtgttg attgatgaac ccgatttact attactagac gaaccaacaa accatttaga
     3361 ttatgaagcg atcgagtggt tggaaaacta tttgaaacaa taccgtggcg cactattgat
     3421 ggttacccac gatcgttatt ttctagatag agtagcaaac cgaatcttcg aactttcatt
     3481 tggaaaatta tacgagtata aaggaaatta tgaagcttac gtcttagaaa aagcagaacg
     3541 tgatcgtgta gaagtagaac aagaagaaaa gcgcaagcgg ctttataaac aggaattagc
     3601 ttggatgagg gctggcgtac aggcacgtgg caccaagcag caagcacgga tcaaccgttt
     3661 cgaagatcta aaggagaact tgtaccaagt aaaccaagaa gatgatttag agctgaacct
     3721 agcgacacaa cgtttaggga aaaaagtact ggaaatcaaa gatggcagtt accgtataaa
     3781 tgaccaaaca ctgctagaac atttagattt attgattcaa tctcgggaaa gactaggtat
     3841 tactggtaaa aatggtgcgg gaaaatcgac attgcttaat attctagctg gcagaattcc
     3901 cctggatagc ggtacaatgt ctatcggtga aacggttcat cttgcgtatt atacacaaga
     3961 aaatgaagaa atggcaccag ataaacggat gattgcttac ttacaagaag ctgctgaaga
     4021 agcaaaaaca gcagatggca gtcaaatcgg agtagcagaa ttacttgaac gatttttatt
     4081 tccaagattt atgcatggga cactgatagg caaactttca ggcggagaaa aacgccggtt
     4141 atttttgttg aaactgctga ttcagcaacc taatgtttta ttattggatg aaccgaccaa
     4201 tgatttggac atagcaacat tgacgatttt ggaagattat tttagaagtt ttccaggtgc
     4261 tgtgatcact gtttcccatg accgttattt cttggacaag gtagcagata agttattagt
     4321 attccaagga aacggaaaac aagaacttta ttacggaaac atgtccagtt atttactgaa
     4381 gcaaaaagag acccagcagc ctgctgaaaa agcgaaacca aaaatacaga gcaaggaacc
     4441 tgctgaaaag aagaaattat cttacatgga acaaaaagaa tgggaaacga ttgaagatga
     4501 gattgcagaa cttgaagaaa aaatctcatt gctccaagaa gagatgaatc atcaaggaga
     4561 taatttcact cgattacaag aattgcaaaa cgacgtatct gaaacagaag cacaacttga
     4621 agaaaaaatg gcacggtggg aatacttgag tgaatgggta gaagattagg aggaaaaagg
     4681 atggaacaag cgtatcttga cttaggaaga aaattgttgg aagaagggca tcgtaaagaa
     4741 gacagaacag gcacaggcac attaagctta ttcggatacc aaatgcggtt tgatctgcaa
     4801 aaagggtttc ctttgttaac aacgaaacga gtaccttttg gattgatcaa aagcgaattg
     4861 ctttggtttt taaaaggaga tacgaatatc cgctatctat tacaaaataa aaaccatatt
     4921 tgggatgaat gggcatttga acgctacatc aaaagtccag actataatgg accagatatg
     4981 actgattttg gccatagatg tttgacagat cctgaattca atgaagaata taaaaagcag
     5041 agcaagcttt tttgcgagaa gatcctaacc gatgattcct ttgctgaaac atacggcgat
     5101 cttggacaca tctacggcta tcaatggcgt cactgggaaa caaaagacgg tggctttatc
     5161 gatcaaatca aacaagtgat cgaagcaatc aaaaagactc ctgattctag aagattgatc
     5221 gtttctgcat ggaatccgga agatgttcct agcatggctt tgcctccttg tcatacgatg
     5281 tttcaatttt atgttcaaga gggacggcta agctgccaat tgtatcaacg cagtggggat
     5341 gtgtttctag gcgttccgtt caacattgca agttatgcgt tgctgactca cctaattgca
     5401 catgaaacag gtttagcggt tggcgaattt gttcacacat taggagatgc tcatctttat
     5461 atcaatcata tcgaacaaat gaaagaacaa ttgagccgag aaatacgcgc atttccgact
     5521 ttagttttga atcaggaaaa gcagtcagta tttgattttg agatggaaga tatccaatta
     5581 gaaggatatg acccacatcc ggcgatcaaa gctcctatcg ctgtttagaa tcagaaagga
     5641 tgagaaaatg ttagctgcaa tttgggcaca ggatgaaaac ggattgattg gaaaagaaga
     5701 ccgtcttcct tggcgtttgc caaatgatct gaaattcttc aaacaaatga cagaagcaaa
     5761 tacactagtg atgggacgaa aaacattcga agggatgggt agccgtccgt tgccgaatcg
     5821 tcagacgatt gttttgacga gagattcttc ctataaagca gaaggcgtgc atgtcatgca
     5881 tagtgtggaa gacgtgcttg ctctggaaaa agaaacagac ggtatctttt tcatcgctgg
     5941 agggtcagct gtttatcaag aatttctgcc attttgtacg atattatacc gtacagtcat
     6001 ccatcatgta ttcgatggag atgcttattt tccacctgtt gactggtctg attggtcact
     6061 gatcaatact agtcaaggag aaatggatga aaaaaatcgt tatccgcatc aatttgaaac
     6121 gtatcagcgt aatgagaatc ctgtaaaaag cgggacaggc gaattgacga tataaaaaag
     6181 ctatggatag actagctgtt atttagagct gtcccatcca tagctttatt ttttttatta
     6241 agtaaagaat aaaacagaga agtacataaa acctgcacct aacataacaa acaaatgcca
     6301 aacaacatgc atatagcgga tagaattcaa gctataaaag aatgcgccta tcgtgtaaga
     6361 aagcccgcct gctaccatca aaataacacc agtcattcca agagagtgat aaagaggaac
     6421 agcagccacg acacagagcc accccataaa aatatagatg atcgtagata cttttgatac
     6481 tctctcccgt ttatgcaacg tcaacgcttt atatataatg ccaagaatcg caaacaacca
     6541 gattaataca aataaagtcc aacctagcca tcctcggata ctcagcaaac aaaaaggagt
     6601 ataacttcct gcaatcaaaa gaaaaatcga actatgatcg aatacttgga acaccttttt
     6661 tgcttttgta aaaatcaatg aatgaaacaa agtagacgtt aaaaataaaa gaatcatcat
     6721 cgatccatag atagcataag agacaatatg gagggaggaa tgcaagtggg caccttttac
     6781 taaaagaacc actagtcccg cgatactcaa tccagtccca attccatggg tgactgcatt
     6841 aaacacttca tttaatattt catacgttcg attaaatttc gttttttcca tgaaaacggc
     6901 tcctttacta ggtgtaatta atgaaaaatc attatttgtc tgttatacta aaaatagaaa
     6961 ttgtcttaca tgtagtttaa catgaataag gcatcttgtt aaagaaagag agagagaaaa
     7021 taatgacaaa tgtaaaaatc gtaacagatt cttcatgtac gatggaaaaa aatgtacgcg
     7081 atgctttagg cattcgtgtc atgccgctat ccatcatgat cgacggaaca gtatatcccg
     7141 atgatgacca actagacggc gaaagattta tggaaatgat ggcgaaagca aaaaatctgc
     7201 ccaaaacaag ccaaccacca attggagaat tcatctcgat gtatgatgag ctaggagaag
     7261 acggcagtga agtgatttcg atccatatga caaaaggctt gagtggaaca gtagaagcag
     7321 caagacaagc cagtaatcta acaaaaacga aagtaacggt tatcgacagt gataccactg
     7381 accaaggatt atcttttcag gtaattcgag cagctgaatt agcaaaagaa ggtaaaacag
     7441 tagagaaaat ccttgaagaa gtcaaaaaag tacaagacaa tacaaaatta tacatcggaa
     7501 tatccacact agataacttg gtaaaaggtg gaagaatcag ccgaacaact ggtttgctgt
     7561 ctagtgtttt gaacatacgc gtggtgatga atttcgccca ttctgaatta atccctgtaa
     7621 ctaaggggcg aggaaagaaa acgttcgata aatggtttaa taatttgaaa aatgaactga
     7681 aagaattgcc aaatgtgcga caaatcggta tttcacatgc ggatgcaaaa gaattggcgc
     7741 aagaattcaa agagggtttg caagaattat tcccggacat gcatatccct gtactgcata
     7801 cgaatccggt tatcgctacg catactggta aagacgcgtt tgcaatcatg tattatgtag
     7861 attagtcgaa aagaggataa gccctcagcc tgaaaggctt gcagcttatt ctctttttct
     7921 ttataaaatt aggaaaataa ttgttttctt ttttcataaa gactaccttt ttgataaaat
     7981 ttttgataac attagaacca atcgaataca agaggtgaaa aaatgaaatt aacgaaacga
     8041 catttgatcc tcgttttgtt cccattatta attgcgatca tcatctatgc aggtttagct
     8101 gcttctatac cgaaagctgg cccactaatg aaaccagtaa ctactgtgag agaagatcca
     8161 aataaaaaag aaaaacttca ctacatagct atcggagatt cgctgactga aggagtagga
     8221 gatcaaacca agcaaggagg attcgttccc cttgtcgcaa atgatctaaa agaccgttat
     8281 aatttgaccg cggttgaaac agaaaactat ggtgtaaatg gtgaacgaag tgaccagatc
     8341 ttaaagcgag taaaaacaaa agaagaaatt cgaaacaata tcaaaacagc tgattttatc
     8401 acactgactg ttggcggtaa tgatttgatg aaagttatcc aaaataattt attcgggtta
     8461 acggtcaatt cctttaaaaa gccactgaaa aactatcagg aaaatgtcac agaactattg
     8521 gaagaatttc gatccctcaa taaaaccgca cctatttaca ttttaggcat ctacaatcca
     8581 ttttatttga actttcctga gatcactgac atgcagacaa ttgttaacaa ttggaacaaa
     8641 ggaacagaaa cggtgacaaa aaaaatgccg aactgctact ttatcccaat caatgatttg
     8701 ctttatcaag gattgaatca ggaagtaggt gtcacagaag aaggaacaga tcaaacaact
     8761 agcacgacag aaaatctaaa tggcatcaaa aataatgtgc tctatgaaga agatcatttc
     8821 catccaaata atttaggtta tcaattgatg gcaaatgcag tgagagatca gctgatcgag
     8881 acacaaaacc aatggttaga gaaggaggat gatcaataaa catgaaaaca agatctgacg
     8941 tatcttcaaa caaaacaaag aaaacaaatt actggaaatt cgccttcctt atccttcttg
     9001 gggtagtact tggttcgacc gtatttttag gcagccgtat ttttgctaat cgggaaccag
     9061 aactcccaga aataccagct cttacggaaa gacaaggaga tcctgtctta acgatcaatt
     9121 caaataaaga aaaagtcaat caaatcatca gctttttcct tagtgagtat caaaaagata
     9181 gtgatattga atataaattt tatttggaaa atgaagcact actcaatggt actttcgaag
     9241 tactaggttt tcctatcgat ttctatttat attttgatcc gtatgtgatg gaaaacggaa
     9301 atgtccaact aaaagctaga agtctttcta tcggaacatt gagtttgcca atcaaagatg
     9361 tgatgaatat gatcaagaga aactataaat taccagattg gatcgaagtc aatacagatg
     9421 atctgactat catgcttagg ttggatcaat tccgaatgca aaacgggatg tatattaaag
     9481 cagataaaat cgacttagta aatgatgaca ttcggtttag tctatatttg ccaaaagata
     9541 cctctgatgc ttcaaacaac tcaaatacca acaaaactag caccagcagt actgaaagca
     9601 agacaaaaga aaataaaaaa tcatcggatg agtagtatta gagggggaat cataatggaa
     9661 cgagcaatat ttgcaggagg ctgcttctgg tgtatgatcc agcctttcga cacgcttcct
     9721 ggtatccata cagtgatgtc aggatatact ggagggcatg taccagatcc gacttatgaa
     9781 caagtaaaaa gccaaacgac tggacataca gaagcagtgg agattatcta tgatccaaca
     9841 ttgatttcat atgaacaatt agtagaactt tactggcagc aaactgatcc aactgacgct
     9901 ttcggacaat tcgaggatcg cggtgacaat tatcgcccgg tgatctttta tttgacagaa
     9961 gaacagcgga tcattgctga aaaaagtaag aaacagttag ctgaaagtgg acgtttcgaa
    10021 cagccaatcg ttacaaaaat cgaaccagcc caaccatttt atctagcaga agaagaccat
    10081 caagagtatt ataaaaagca tcctgaaaat tttaaaagaa accatgcacg ccgggctgcc
    10141 tttatcgaag aaaattggag gaacgaaggg tgaatcgaag cttttttcat tatttaatga
    10201 cactgcgagg cggtggcaca catgatgctt tatctgtttt cgctacagaa gccggtaaag
    10261 acatccaatt tcctaagcac agctctagct acgaagaaat ttctaattat ctggaactga
    10321 atgtcgacta tttgccgtcc atggatatct ttgacgaagc atgggaaaaa tatttagaaa
    10381 ataatcatga catataagag atagttttgt actttatgat caaaaaagtt ttttgtccaa
    10441 tagcctaatt gaaagaatta tttttatttc agctatctag tcgcattttt ttgatatttt
    10501 tcttataata aagaaagaat gaaaaaaaga gggatggatt gatagagatt gacaaaaaaa
    10561 caacgctata ttaatcgctt ctggcttgta ttcaaatact tacttgtttc tgtattcctt
    10621 gcgttcatgt tgcggggatt tttattcatc ccggtaccag tggaaggcaa ttcaatggaa
    10681 aacgtgttga agcaaggtga tatggttgtg atggaaaaat tttcggagat cagacgattt
    10741 gatattgttg tttttcaatt agcagatggc acgatttata tcaaacgagt aatcggtctt
    10801 ccaggagaaa atgtcagcta ccaaaatgat caattgaaga tcaatgggaa agtagttaag
    10861 gaaccttatc taactaaaaa cctgaaatca gatcatgcaa atgcatccta tacgacggac
    10921 tttacactac aagagctaac gggacaatcc aagcttccgg aagataatta ttttgtactt
    10981 ggagataatc gaagagtttc aaaagatagt cgttcgtttg gcacgatcaa taaaactgat
    11041 attctaggta aagcaagatt tgtctattat ccacttgatg aaataaaatg gatccagtga
    11101 gaaacaataa agcgtgcagt ctgttgagac tgcacgcttt attgtttaat ccaaaatcag
    11161 tttactacct tagtacgtaa aatcaaacag ctcgtttaaa cacttttcta gcctctaaag
    11221 ttttgataaa tgaataaaca accattattt gaatagggat ttggatcata ttcctgatga
    11281 atctacctag aaaaattact ttgaaatctg caccaaacaa aacagacatc agccaagaat
    11341 tgataaaaag gctgactggg atcataatca ataattgggc agcgatgacg gaaggcaggt
    11401 ttatcttttt atgatataaa aataagccat taataaatcc accaaggaaa gccgtgataa
    11461 gaaaagcagc ttgaaacgtt cctgaaccaa atatcgtgaa atttaaagtg ttcgacaaca
    11521 tttcaagcaa accagcccag atcggtccat atagataacc cataagcgcc atacttaaaa
    11581 atccgaatgt gatttgaaaa taagcaggac caatcgctat cttgtataag atgacatcaa
    11641 gggctaataa aagagcagag gtcgacaaca atcttgcatt catttcgggc aatctaaaaa
    11701 cgtcttttgc aatcaaagtg ttcaaaatat tctctccttt gtcagttaat aataaaagga
    11761 taccataaaa tcaccaatgt gtcatgacac attggtgatt tacatacact ggcatctaac
    11821 aattaaaaaa agggtgagaa gactgctttt ataaactgta aaaaagagat tgtacgaata
    11881 aaaaaaatag aggcggagaa tacttatcgt atcatccgcc tttgtttttt tgttataaaa
    11941 aacgtcagat tagttatctg cttacatctt catccatacg ggttctaatg tatttccgtc
    12001 tagatcttgg acttctaatg aaaacatttc ttcttcaggc attcccatat ctacttcgtg
    12061 gaaagtacca ccattttctt ttgcaatttg agcaaatttt tttacttcat ccgcattttc
    12121 aacactaaac gaaatcaaag caccacttgt ttttttatta tcagctattt ctttatcttt
    12181 tataaatttt ttataaaaat catgagagag aagcattatc caaaaagtgt catcccatac
    12241 cattgaacca gcttcttcag tagaaaattc ttcatttttt ttaaaaccca gcttttcata
    12301 aaaagcaacg gaacgattga catcagcaac aggaaaatta acaaaaacca tactattcat
    12361 ttgtttcgtc tcctttctgt tttgttcgtc tatcatctct tatttaggaa acgctgtcaa
    12421 aaatttagat tcatatatag aaaccaaaat aaaaatttgc atcatcaaaa aagtgaagat
    12481 gtgatagaat gaggactggt tcactttcac ttaactaata gatggaattt ctttataata
    12541 aaaaagtgaa tttatattga aaaagaaaaa aacaagtaaa gccggggaat attccggtat
    12601 gaaaggaatg gagagaacaa tgaccatcca atggtttccg ggacatatgg caaaagcccg
    12661 acgagaagtt tctgaaaaaa tgaaatatgt ggacatcgta tttgaattgg tagacgcacg
    12721 attaccttta tcttctcgta atccaatgct agatcagatc attcagcaaa aacctcgcct
    12781 tgttttattg aataaagcgg atctggcaga tccacaacag acaaagctgt ggcaagaata
    12841 ttttcgtaaa caaggccatc ttgcattagc tatcacggca caagaaagta aaggaattaa
    12901 aggtctagta cctgcggcta aagaagcatt gaaagaaaaa cgggcaagag atgctgctcg
    12961 ggggatcaag cctcgcgcta ttcgggcaat ggtcttaggt attccaaatg ttgggaaatc
    13021 tacgttgatg aatcgactag taggcaagaa aattgcacag acaggaaata agcctggcgt
    13081 aacaaaaggt cagcagtggc ttcgtttagg taatgagttg gaattgttag acacaccagg
    13141 gattttatgg cccaaatttg aagatgaaga aatcggcaaa aaactagcgc tgacaggcgc
    13201 gatcaaagac cagcttgtcc atttagatga tttagcgatt tacggattag acttttttgc
    13261 ccgatattat tcaggaagaa tcagcgatcg ttatggttta tcaatcgagc aagaagaaaa
    13321 attggcaccg gaattactga tggatattac agcaaaacgt gggtataaag aagactatga
    13381 tcgtggcagc gaattagtcg tgcatgatat tcgtcaagga aaacttggac gatacacact
    13441 ggatcgttgc gaagaaatgg agcaaaaaag tgatgactga atccatccaa agtatcaaag
    13501 aacgattgaa aagcatacag agaatagatg atcctacact agaatcatta agaaatgatc
    13561 cacgcaaagg cgtgcagcaa gcactggctt cttttgaacg acgattgaaa aaggaagcat
    13621 taattaagga aaaatatgaa gaaatgtttt gctttgaaaa gcaagggtac gcacaaggtc
    13681 accaatggat tgccggcatt gatgaagtag gaagaggacc attagctgga cctgtcgtgg
    13741 cagctgcagt tatcttgccg aaaaatgaga tcatattagg gctgaatgac tccaaacaat
    13801 tatcagagaa aaagcgagaa cttctttatc aacaagttca agaaaaagcc ctggcaatcg
    13861 ggatcgggat cgttgatcag cagacaatcg atgatgtgaa tatttatgaa gcaagtaaat
    13921 tagcgatgat ccaagcagta gaaaaattgt ccattgtacc aagctatttg ttgatcgatg
    13981 cgatgacctt ggatttgcct attcagcagg aaaaaataat caaaggggat gcacgatctg
    14041 tgtcgattgc tgctgcaagt atcattgcta aagtatatcg agaccaattg atgaaagaat
    14101 atgacgtgct ttatcctgga tatggtttct cgcataatgc aggttatgga acaaaggaac
    14161 acttagaagg acttgaacga caaggaatta cgccaatcca tcgtaaaagt tttgcacctg
    14221 taaaaaaata tttacaataa aaaacagccg cttttacgta tcttattaga aagagagacg
    14281 aaaggcggtt ttatgatgta tcaaatagaa gaaaatttat tgaaacttgc ttatacaaaa
    14341 ggaatcagta gtcaaggaaa atgggcactt gctaactgga tgatgcagta tccttataaa
    14401 gaaatcggat ttgaagacat cattaagata ggtaaaataa ccaaacaccg ggagctgttt
    14461 cgcaaaagtt ggcaggaaat tcacgctaac tggggcaaaa tccaatcgaa acagtcgttt
    14521 atcacttgct ttgatcccaa atatccccct cagctgcttc acttgaccta tccgccaatt
    14581 gtactgtttt ataatggtga tctatcttta ctttcttgta acatgttaag cgttgttggt
    14641 ggaagacaca cttctgcttt agccaaaaaa acagtttatt atttactaaa accagtgata
    14701 gaagctggat atgtgatcgt cagtggctgc gcgaaaggga tagatacata cggtcaccaa
    14761 gcagcaatct ctcatggtgg acggacaatc gcagtcattg gaacagggat agagcaagtc
    14821 tatcctgctg aaaatcgtga cttgcaagag gtgattgcaa atgatcatct tcttttgagt
    14881 gaatatcctc ctcaatccgg cccgaaaaag cattgttttc caatgagaaa tcggattatc
    14941 gcagctttgt ctaaaggaac atgtgtcttt gaagccaaga aaaaaagcgg ctctctgata
    15001 acagcacagc aagcattgga tcttggaaga acagtttttt ctgttccagg aaatatttta
    15061 acagaacatt ctaccggatg tcatcatttg atccaagacg gtgcagtttg cacggtttcg
    15121 ggtgaagata tcttggcaga atttaaagaa taacaccata cttttcattt gcttttcttg
    15181 acaaacgttt tctgaatgga tatgattagc tacgatttgt atgaatcctc ttttaatagt
    15241 aggaacacga caatggaaag gagtccattc agtaatggcg tataaatatt tagtgattgt
    15301 agaatcacct gcaaaagcca agacaattga gaaatatctt ggacgaaact ataaagtaat
    15361 ggccagtgtt ggccatataa gagatttacc gaaaagtaaa atgggtatcg attttgaaaa
    15421 caattatgaa ccccattata tttctatacg cggaaaaggc gatgtcatca aaagcctgaa
    15481 agccgcagca aaaaaagctc aaaaagttta cttggcaagt gacccggata gagaaggaga
    15541 agcgattgct tggcatttag cgtacctact tgggttggat ctgaaagaaa aaaatcgggt
    15601 ggtcttcaat gaaatcacaa aagacgcagt caaagcagct tttaaggaac caagaacgat
    15661 cgatgtagat ttagtagatg cacagcaagc tcgtcgtacc ttagacagaa tcgttggtta
    15721 ttcgatcagt cctattctct ggcgtaaggt caagaaaggg ttaagtgcag gacgtgtcca
    15781 atctgtcgct ttaaaaatta ttattgaccg tgaaaaagag atccgagaat ttgttccaga
    15841 agaatattgg agcatcgacg gtaattttaa aaaagctcgc aagaaattca aagcaaattt
    15901 ctggggaatc gacggtaaga aaaagaaatt accagatgca caaagtgtaa aagaagtcac
    15961 tgctagaatt gatggaacag acttcgaagt taaaaaagta gaaaagaaag agcgcaaaag
    16021 aaaccctgcg aatcctttca ctacaagtag cctgcaacaa gaagctgccc gtaagttaaa
    16081 ctttcgaaca agaaaaacca tgatggtagc acagcaatta tatgaaggaa tcactttggg
    16141 taaacaagga acagtcggct tgattacata catgcgtact gattctaccc ggattgccga
    16201 tacagcaaaa gcagaggccg cagcatttat tgaagatacg tatggaaaag aattttctag
    16261 acatgatcac cgaaagatca aaaatgctca aggcgcacaa gatgcccatg aagctgtgcg
    16321 tccaacgagt gtgcttcgta caccagatga actcaaacaa tatttagata aagatcaatt
    16381 gaaactttat acattgatct ggtcacgttt tgtggctagt cagatgacac cagctatttt
    16441 agatacaatg aaagtgacat tagaacaaaa tggtgtcatc ttcattgcga acggttcaaa
    16501 aatcaaattc aaaggattca tgcaagtgta tgtggaaggt agagatgacg gcaaagaaga
    16561 gaaagaaaat attcttccag aacttgaaga aggcgatgta gtccaatctg ttgatattga
    16621 accaaaacaa cattttactc aaccaccagc acgttttagt gaggctacgt tgattcgtgc
    16681 actagaagaa aacggggtag ggcgaccttc cacttatgca ccaacacttg atacgatcca
    16741 aagacgctac tatgtaaaat tgacacaaaa aagatttgag ccgactgaac taggagaaat
    16801 tgtcaattca ttaatctgtg aattcttccc tcaaatcgtc gatatccatt tcacagcaga
    16861 aatggaagga gatttggata aaattgaaga aggcacggaa gcgtgggtca aagtggttga
    16921 tcgtttctat aaaccgtttg aaaaagaact gacgaatgcg gaagaaaaaa tcgaaaaaat
    16981 tcaaatcaaa gatgaaccag caggattcga ttgtgatgtc tgtggacatc cgatggtgat
    17041 aaaattaggg aaatatggga agttttatgc ttgcagtaat tttcctgatt gtcggaatac
    17101 gaaaccaatc gtaaaagaaa tcggtgtgac ttgcccagta tgtcatgaag gacaagtcat
    17161 tgaacgaaaa tctaagaaaa acagactatt ctatggttgt tcccgtttcc cagaatgtga
    17221 attcacttct tgggataaac cagtgggcag aaattgtcca aaatgtgacg gatatctggt
    17281 cgagaagaaa gtcaaaggcg gtaaacaagt agtctgtgta aatggagatt acgaagaaga
    17341 catccaaaaa taatagaaaa gaggttcttt cattgaaaat ggtaaatgtt gttggagcag
    17401 ggcttgccgg aagtgaagct gcttggcaga tcgcacaagc aggagtccct gtccgtttat
    17461 atgaaatgcg tccagtcaaa tcgactgagg cgcatcacac aagtaatttt gctgaactag
    17521 tatgttccaa ttcattaaga ggaaacagtt tggctaatgc agtagggtta ttgaaagaag
    17581 aaatgcgccg attgaattcg gtagtaatca cttcggcaga tgaaacagca gtgccagctg
    17641 gtggtgcctt agctgttgac cgcgattctt tttctgaaac aattacccga aaagtcaaag
    17701 agcatccatt agtaacagtg ataaacgaag aaattactga aataccggaa ggaatcaccg
    17761 tagtagcaac aggacctttg acttctcatc cattagcaga aagcatcaaa gcattcaatg
    17821 gttcagatgg tttttatttc tatgatgcag ctgcaccaat cgtagacaaa gctacgatcg
    17881 atatggataa agtatatttg aagtcccgct atgacaaagg agaagcagct tacttgaact
    17941 gtccgatgac agaagaggaa ttcaaagctt tccatgaggc actaatcaat gccgaagtgg
    18001 cagaacttaa atcttttgag aaagaaaaat attttgaagg atgtatgcca attgaagtaa
    18061 tgggacagcg aggattcaaa acgatgcttt tcggacctat gaaaccagtt ggattggaag
    18121 atcctaaaac tggcaaacgt ccttatgctg ttatccagct gcgtcaagac aatgctgcag
    18181 cttctttata caacatcgtg ggctttcaga ctcacttgaa atggggcgag caaaaacgtg
    18241 ttttccggat gattcctggg ttagaaaatg ctgaattcgt tcgctatggt gtgatgcacc
    18301 gaaacagctt tatgaattcg ccagaattgc tgaaaccgac ttaccaatca acgaaacgcg
    18361 aagatctgtt ctttgcaggt cagatgactg gtgtagaagg ctatgttgaa agtgcagcga
    18421 gcggactact tgctggaatc aacgccgcac gcttagcaaa agaaatggaa ccagtcgagt
    18481 ttccacaaga aacagctatt ggaagtatgg cttactacat tactcatgcg gaaggaaaac
    18541 atttccaacc gatgaatgcc aactatggtc tgtttcctga actgccagag cgcattcgag
    18601 acaaaaaagc aagatatgaa gcaattgcac aacgagcttt aaaagctaat gaggcaataa
    18661 aaacagaatt agaaaaaact gcaatcccaa atgagtaagg aaactccatg aagagggtga
    18721 gacggatagt ctcgctcttt ttcttgcgtt tttcttaaga atttctcaaa caaaatgtga
    18781 ggaattgcgc caattgtgaa caaacttaga aatattggtt aaattctgac aatttatttg
    18841 tctttttata aacgctgtgc taaattattc tctgggacaa aaggaaggtg agaaaatgac
    18901 agaagccacg tgggaacaaa aatttttgcg ttatttgatt gtcgaaagag gatattcaga
    18961 aaaaacgaaa gaagcatatg aagaagacat tctccatttc aaacattttt tggaggaatc
    19021 tggagacgct gatctgctga aggcggaata ttttacggtt cgtgtctatt tgagtgcatt
    19081 agctgatcat cgtcctagct atagcagaaa ttctatcagt cgcaagatag ccagcctacg
    19141 ttcgttttat cagtatcttc tcaaagaaga agtgataaaa gaaaatccat tttcttacgt
    19201 tcatctcaaa aagaaaaatt tgagactgcc acgttttttt tatgaaaatg aaatgcaagc
    19261 actttttgac agcgtagcag gagatagtcc tttggatttg aggaaccgcg ctttactgga
    19321 agtcctttac gggtcaggca tccgtttaag tgagtgtagc agtttgtcgg tatcagacat
    19381 tgattttgat tcagaggtca tgttgatcca tggtaaaggg aacaaagaga gatatgctcc
    19441 tctaggttct tttgctcaag atgctctgca agaatatttc agggaaggcc gccaggtatt
    19501 gatgacaaaa tatcacgaag agcatgatat cgtttttgtg aatcatcatg gaaaaccaat
    19561 cacgcctact ggaattgaat atgtcttgaa tcaaatgatc aaaaaaagca gtttggatag
    19621 tgatatccat cctcacatgc tgcgccatac atttgctact catttattaa ataatggggc
    19681 agatttgcgg acagtccaag aattgctagg acatgccaat ttatcgacta cccagatcta
    19741 tgcccatgta acaaaagaaa gtttacaaaa aaactatcgt tctttccatc caagagcgta
    19801 aaaataagga aaagaacaaa tttaggagga aacaaacatg gtcgaatcac catttcattc
    19861 aaccactatc tgtgccgtcg aaaaagacgg gaaatttgct atggctggag atggccaagt
    19921 aacaatgggt gaatctgttg tcatgaaagg cactgcaaag aaagtacgac gtatctacaa
    19981 tggagaagtt gttgtaggtt tcgccggaag tgttgcagat gcgtttactt tagaagaaaa
    20041 atttgaaggc aaactaaacg aatataacgg gaatctacaa cgcgcagctg tcgaattagc
    20101 tcaagaatgg cggacacagc aatctatgca aaaacttgaa gcgatgctga tcgtaatgaa
    20161 tgataaagaa atgcttcttg tttcaggtac aggagaagtt atcacaccag atgatggtat
    20221 cttagctatc ggatcaggag ggaattttgc gttggctgca gcccgagcaa tgaaaaacta
    20281 tgctcaaaac gacatgagtg cgaaagaaat tgcagaaaat gcgttaaata ttgccgcaga
    20341 tatctgtatc tttactaatc ataatattat cgtagaagaa ctgtaagagg tgagtagata
    20401 tgtatgaatt aaaacaaaca ccaagacaaa tcgtaagtga attagatgaa tatatcgtag
    20461 gacagcacgc agcaaaaaaa tctgttgccg ttgctttgcg taaccgctat cgccgtttgc
    20521 agttagatga aaaaatgcaa caagatatta caccaaaaaa tatgctgatg atcggaccta
    20581 caggggtcgg taaaacagaa atcgcacgac gtttggcaaa aatcgtcaat gcaccatttg
    20641 tcaaagtcga agcaacaaaa tttactgaag tcggttatgt cggaagagat gtagaatcaa
    20701 tggttcggga tttagtagaa aatgcgatcc aaatcgtaga aaaagagcag tacagccgtg
    20761 tatacacaag tgctaaaaaa aatgcagaaa aacgtttggt aaaaatcttg gtacctggta
    20821 tcaaaaaaga acagaaacaa tccactaatc aatttgaaca aatgatgaat ctttttaatg
    20881 ctagtcagca aaataccgct gaaccgcaag aagaagtgac agaagatatt cgaatcaatc
    20941 gccgtacagt cttggaacaa ctacaaaagg gtttactgga tagtcgtgaa gtaaccattg
    21001 aagttgaaga ccaaaagaaa cctgcaccaa tgatgaacaa tggattggag caaatgggga
    21061 tcgacctaaa tgaaactcta ggtgctttga caccgaagaa aaaagtggaa cggacggtaa
    21121 cagtcaaaga agctttagag ttattgatca aggaagaatc agcaaaatta gtcaaggatg
    21181 ctgatatcca tagtgaggca atcaaattag cggaagaaag tggaattatt tttatcgatg
    21241 aaatcgataa gatcacttct aaatcacagc aatctggaga agtatccaga gaaggcgtcc
    21301 aaagagacat attgccaatt gtcgaaggtt cacaagtaaa cacaaaatac gggatcatcc
    21361 aaacagatca cgtcctattc attgcttcag gagctttcca tttgtctaaa ccaagtgatc
    21421 taattccaga acttcaagga cgcttcccga tacgggtaga attagatgat ttgacagctg
    21481 aagattttgt gaagattctg accgaaccaa ataatgcttt agtaaaacaa tacgtcgcgt
    21541 tgatcggtac agaaaatgtg tcagttacgt ttacaaaaga agcaattgaa cggatcgctc
    21601 aaatcgcttt cgatgtcaac cgtgacacag ataatatcgg cgcacgcaga ctgcatacca
    21661 ttttggaaaa actactagaa gatctattat ttgaagcacc agatatgcaa atgggagaaa
    21721 taacgatcac agaagcatat gtggatgaca aacttggctc aattgcggca aatgaagatt
    21781 taagtcgcta tattttataa aaaatcggag gacgacaatg acagacttgc taacgaaaac
    21841 ccgcaagata aacacacttt tgcagcaaaa gaatactttt gacatgcaag cagatttgcc
    21901 ttacgataaa atggctgtca cactaggtgg tattcttgac agcaacacct atatcatagg
    21961 aagtgacgga gtattactag gttataatga acgtcacgat gtgaacaatg aacgaatcaa
    22021 aacaatgttt gttgagaaac aatttcctga atcttatact gatacagtgg cacagttgat
    22081 gaaaactgaa gctaatatcc caattactag tgatattact gcatttccgg tagagtcaag
    22141 agagaaatat ccatttggtc tgacgactgt cgttccgatc tttggagctg gcgaacgttt
    22201 gggtacgatt atcttatctc gtatggaaca atcgtttgca gatgacgatc tagtcttagc
    22261 agaatatgga gctacggttg tcggtatgca gatcctttat cagaagtctc gaagcatcga
    22321 agcagatgta cggagtgcaa cggctgtcca aatggcaatc aacacattat cttatagcga
    22381 attgaaggct gtacaagcta tctttgaagc attggatgga gatgaaggtc gtctgactgc
    22441 ttctaatatt gccgatagta tcggcatcac tcgttctgtg atcgtcaatg ctttacgaaa
    22501 attggaatca gctggaatca ttgaatctcg ttcgttaggc atgaagggaa cttatttaaa
    22561 agtattgaat tcccgtttta aagacgagtt agcaaaacac agttattaga agtaagggga
    22621 ctggggcaga tagaaatgtt tgttccagcc ttcccatttt aaaaagtaag tcgaagttgg
    22681 aggaatggca atgactgtta ttattcaaaa tgaccagctg atcgccgaaa tcgctgaaca
    22741 cggtgcggaa ttgatcagtc tgaaatcaaa agaacatggt ttagagtata tctggcaagg
    22801 tgatccagcg tattggggca gacatgcacc ggttttattc ccttttgttg gacgtttaaa
    22861 agatgatcag tatgtttatc aagggaaaac atatcaaatg gggcaacacg gatttgctcg
    22921 ggatatggat tttgaagtca ttgaacatgg acaagaaatg gctagtttca tcttaaggag
    22981 tacgccggag acattagaaa agtatccatt tgattttgaa ttagtgatca gctatgaatt
    23041 aggaggagac ggcatcacgg ttcattatca agtggcaaat accggtgaaa aagaaatgtt
    23101 cttttctatc ggtggacatc ctgctttcaa tgtacctctt gaagaaggat tgtcatttga
    23161 agatttctat ctggcatttt ctccattgaa atcaagatta cgcctaccat tgaaaggccc
    23221 attcatcgat atggatcaaa agacgttagg tcagacaaat acgaatctgg ctttgaatcg
    23281 tgaacttttt gagcaagatg ccttggtttt tgaaacaagg ggtctaaatg cgtacgccat
    23341 tcgaagtgaa aaatcttccc atagcgtaac tttaagctat aaagatatgc cttatgtagg
    23401 gatctggtct ccttatccaa aagaagcgcc tttcgtttgt atcgaaccgt ggtgcggaat
    23461 cgctgacacg gtgaacagta gtggaaactt gatggaaaaa gtagggatca atcaactagg
    23521 tgcccatgaa atcttcaaga caaaatattc catcacagtg aagtaagagg ttgtgaccga
    23581 gaagttagca gggaacaccg tttaccaagg tgtgtaaaaa agctatcctg taagtaataa
    23641 gggagtgtga catcgatttg tggctctttg tcaataagga ctgatgagtt gtgcaaaatc
    23701 aaatctgagt cagaatgaac cacattctgg ctca
//
LOCUS       DAFBVQ010000041        23576 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.042, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000041 DAFBVQ010000000
VERSION     DAFBVQ010000041.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23576)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23576)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23576
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.042"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            43..675
                     /locus_tag="LLC22_001810"
     CDS             43..675
                     /locus_tag="LLC22_001810"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pentapeptide repeat-containing protein"
                     /protein_id="HBK5435088.1"
                     /translation="MKKIEPIPPSLPLLTKGEFYLEDEEIFSGLLINGGDQSYLDAKN
                     MVLRESHIQKLTMQKTVLRHFECSNVIFEKCDFSNLEWIGGSFHQVVFHQCKLTGTNF
                     AESYLRDCTFTDCIASMASFSSTNLKAVSFDHCQLEDSEFYEVTWKNLFLSDNQLTGS
                     NWFRTSLKGLDFTTNFFTAIALSQDSLAGLIVNQEQALVIAQALGLQIKD"
     gene            complement(677..1582)
                     /locus_tag="LLC22_001811"
     CDS             complement(677..1582)
                     /locus_tag="LLC22_001811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK5435089.1"
                     /translation="MREKHYFNQDRNFWINVQQNDVLAVKNLKEEYGISDEMLTYSLD
                     KNERARVEYDSFDEALLLVSNVPHQQKVDNHYETSPIAFILKEDGLFTFTTPNTEYVI
                     RLIRSLLERMPDMSVYSLLFRTLFLISDSFFPLIEEVNSERQRLNLKLREKTTNKNLL
                     QLSDLEIGLVYLVTGTKQNVVLLEQIKALAIYRKLSEKEKEELDDALIEARQAVEMTN
                     LASQILDQLSGTYNNLLNNNLNDTMKFLTVWSLILTVPTIVTGFFGMNLQLPFTHSVF
                     GWGIALIISLVLSIWMLIALWRRIR"
     gene            complement(1667..2326)
                     /locus_tag="LLC22_001812"
     CDS             complement(1667..2326)
                     /locus_tag="LLC22_001812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="deoxynucleoside kinase"
                     /protein_id="HBK5435090.1"
                     /translation="MSVIVLAGTIGAGKSSLTEMMAEHFDSQAFYESIDDNEVLPLFY
                     ANPEQYAFLLQIYFLNKRFASIKQAMKDDNNVLDRSIYEDSLLFHLNADLGRATETEV
                     RVYDELLENMMEELPYAAHKKHPDLLVHIRVSFDTMLERIEKRGRSYEQLSFDPSLYD
                     YYKELNRRYDQWYEEYKESPKIQIDGDRYNFVEDPQAKEEVLKMIEEKLAEIRQTKVA
                     I"
     gene            2642..3586
                     /gene="mvk"
                     /locus_tag="LLC22_001813"
     CDS             2642..3586
                     /gene="mvk"
                     /locus_tag="LLC22_001813"
                     /EC_number="2.7.1.36"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mevalonate kinase"
                     /protein_id="HBK5435091.1"
                     /translation="MANYGQGESSGKIILMGEHAVVYGEPAIAFPFYATKVTAFLEEL
                     DAMDDQLVSSYYSGNLAEAPHALKNIKKLFIHLKKQHDIQKNLQLTIESTIPAERGMG
                     SSAAVATAVTRAFYDYLAFPLSREILLENVQLSEKIAHGNPSGIDAAATSSLQPIYFT
                     KGHPFDYFSLNIDAFLIVADTGIKGQTREAVKDVAHLFETQPHETGQMIQKLGYLTKQ
                     AKQAIIENSPETLAQTMDESQSLLEKLTISNDFLNLLIQTAKDTGALGAKLTGGGRGG
                     CMIALAQTKTKAQEISQALEDAGAAETWIQGLGVHTYV"
     gene            3579..4556
                     /gene="mvaD"
                     /locus_tag="LLC22_001814"
     CDS             3579..4556
                     /gene="mvaD"
                     /locus_tag="LLC22_001814"
                     /EC_number="4.1.1.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diphosphomevalonate decarboxylase"
                     /protein_id="HBK5435092.1"
                     /translation="MFKGKARAYTNIALIKYWGKKNEELILPMNNSLSLTLDAFYTET
                     EVIFSDSYMVDEFYLDGTLQDEKATKKVSQFLDLFRKEAGLSLKASVISQNFVPTAAG
                     LASSASGLAALAGACNTALKLGLDDLSLSRFARRGSGSACRSIFGGFVEWEKGHDDLS
                     SYAKPVPSDSFEDDLAMVFVLINDQKKEVSSRNGMRRTVETSSFYQGWLDSVEGDLYQ
                     LKQAIKTKDFQLLGETMERNGLKMHGTTLAAQPPFTYWSPDSLKAMDAVRQLRKQGIP
                     CYFTMDAGPNVKVLVENSHLSEVQETFTKLFSKEQVITAHAGPGIAIIE"
     gene            4569..5654
                     /locus_tag="LLC22_001815"
     CDS             4569..5654
                     /locus_tag="LLC22_001815"
                     /EC_number="2.7.4.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphomevalonate kinase"
                     /protein_id="HBK5435093.1"
                     /translation="MIEVSAPGKLYIAGEYAVVETGHPAVIAAVDQFVTVTVESARKV
                     GSIQSAQYSGMPVRWTRRNGELVLDIRENPFHYILAAIRLTEKYAQEKNILLSFYDLK
                     VTSELDSSNGRKYGLGSSGAVTVATVKALNVFYALNLSQLEIFKIAALANLAVQDNGS
                     CGDIAASCYGGWIAFSTFDHPWLQEQETQHSISELLALDWPGLSIEPLIAPEDLRLLI
                     GWTGSPASTSDLVDQVHRSREDKMVAYQLFLKNSTECVNEMIKGFKENNVTLIQQMIR
                     KNRQLLHDLSAITGVVIETPALNKLCNLAEQYEGAAKSSGAGGGDCGIVIVDQKSGIL
                     PLMSAWEKAEITPLPLHVYSDQRKENR"
     gene            5651..6715
                     /locus_tag="LLC22_001816"
     CDS             5651..6715
                     /locus_tag="LLC22_001816"
                     /EC_number="5.3.3.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319476.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type 2 isopentenyl-diphosphate Delta-isomerase"
                     /protein_id="HBK5435094.1"
                     /translation="MNRKDEHVSLAKAFHDKQKNEFDFVRIIHNPLPQIAVSDVDLST
                     QAVGFTLSSPFYINAMTGGSEKTKKINQDLAIVAREADLMIATGSVSAALKVPSLADT
                     YTIMRQEYPHGKIIANIGAGTSVERAKEAIRLFHADALQIHLNAPQELVMPEGDRDFT
                     NWKVLIQETQTAIDVPLIVKEVGFGMTRETLNDLAALGVHTVDISGRSGTSFTQIENA
                     RRSKRELSYLADWGQSTVSSLLEANEADTSMEILASGGIRNAYDIFKALCLGANAVGT
                     SGTVLTHLMNHGVEETIILMKQWQEELRLLYTMVGATNTAALHQQSLIFSGPVKDWCE
                     ARGIDLVKYGRRTEKSVGQK"
     gene            complement(6964..7767)
                     /locus_tag="LLC22_001817"
     CDS             complement(6964..7767)
                     /locus_tag="LLC22_001817"
                     /EC_number="1.1.1.69"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010741490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gluconate 5-dehydrogenase"
                     /protein_id="HBK5435095.1"
                     /translation="MEFSMDMFRLDGKVALVTGAVYGIGFEIARSLATAGAKIVFNNL
                     NQESVDEGIAHYKEAGIDAKGYVCDVTDEEAVQAMVQQIKEDVGSVDILVNNAGIIKR
                     TPMIEMDAADFRQVIDVDLNAPFIVSKAVIPDMIEKGGGKIINICSMMSELGRETVSA
                     YAAAKGGLKMLTKNIASEYGQYNIQCNGIGPGYIATPQTAPLRETQENGERHPFDQFI
                     VGRTPAARWGEPIDLAGPSVFLASSASDFVNGHVLYVDGGILAYIGKQP"
     gene            complement(7787..8629)
                     /gene="kduI"
                     /locus_tag="LLC22_001818"
     CDS             complement(7787..8629)
                     /gene="kduI"
                     /locus_tag="LLC22_001818"
                     /EC_number="5.3.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="5-dehydro-4-deoxy-D-glucuronate isomerase"
                     /protein_id="HBK5435096.1"
                     /translation="MQEMETRYTHSPEDIRHYSTEQLRKEFLVEKVFEPGKISLTYTH
                     NDRMIFGGVTPTEKELEITLDKELGVDYFLERRELGVINIGGPGFIEIDGQKEEMKKQ
                     DGYYIGKETRHVVFSSQDAENPAKFYISSVPAHHKYPNVKISIDQVKPMETGEGLTLN
                     ERKIYQYIHPNVCESCQLQMGYTILEPGSAWNTMPCHTHERRMEAYVYFDYANEDTRV
                     FHMMGKPDETKHLVVDNEQAIISPSWSIHSGVGTSNYSFIWAMCGENITYTDMDMVQM
                     DQLK"
     gene            complement(8645..9652)
                     /locus_tag="LLC22_001819"
     CDS             complement(8645..9652)
                     /locus_tag="LLC22_001819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331990.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar kinase"
                     /protein_id="HBK5435097.1"
                     /translation="MGKVVTLGEIMLRLSTEQGTRIDSSERFAAHYGGGEANVAISLA
                     NYGHEAIFATKVPDNALGKAVKKHLQCYGVDTKQVLSGGSRLGTYYMETGSGERAASV
                     IYDRAGSSFAEMDHLEWSLEELFQGIDIFHVSGITPALSKKWQKMTKQVIEAAKKAGC
                     LISFDINYRGKLWTQQEASEVIHQLLPLVDICSAGKMDALYLLGIEKAPEAEEQPLIY
                     YYQKMQEKFPNIQVFYSTKRTVHSASENELKGTLWMNHEYVESQVHRITPIVDRVGGG
                     DAFAGGVLHGILSNMSPQEIIDFATAASALKHTIHGDCNQFSQEEVAQFLACGSGKII
                     R"
     gene            complement(9659..10303)
                     /locus_tag="LLC22_001820"
     CDS             complement(9659..10303)
                     /locus_tag="LLC22_001820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional 4-hydroxy-2-oxoglutarate
                     aldolase/2-dehydro-3-deoxy-phosphogluconate aldolase"
                     /protein_id="HBK5435098.1"
                     /translation="MKKIDILSRLKNAGVIAVVRGKSKEEALNACHAIIKGGLTGIEL
                     TFTVPQADQVIKELLSFYKDQPEIVIGAGTVLDAVTARLAILAGAEYIVSPSFDQETA
                     EMCNLYQIPYLPGCMTITEIKTALKSGVDIVKLFPGSAYGPSIISAFKAPMPQVNIMP
                     TGGVSLDNMKEWFDAGVVTVGVGGNLLAPAATGDFDKVTEVAQQYAAKMKEIKR"
     gene            complement(10403..11161)
                     /locus_tag="LLC22_001821"
     CDS             complement(10403..11161)
                     /locus_tag="LLC22_001821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IclR family transcriptional regulator"
                     /protein_id="HBK5435099.1"
                     /translation="MENKKPYGTVLIKASKILDYLAENQDVSLQTIAKGVGMTSSTVL
                     KILDTLLMIGYVNKNSEKNYRLGAKLIRYANKNIEQIDLVELTLPFLEQLQQKIDETI
                     HLGVLDNNEILYVNKLDPKHQTIRMSSKIGITRPLYNSAMGKAVLAEFSEEQYTDYLE
                     KHPLIPYTEYTITNALRLKKEIQTVKETHIAFDDEEIERDIFCIGASIVKNEQIIGAF
                     SVSMPKYRLTDETKEQIISALKQTKSEIEQRIQK"
     gene            complement(11288..12439)
                     /gene="fucO"
                     /locus_tag="LLC22_001822"
     CDS             complement(11288..12439)
                     /gene="fucO"
                     /locus_tag="LLC22_001822"
                     /EC_number="1.1.1.77"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343318.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lactaldehyde reductase"
                     /protein_id="HBK5435100.1"
                     /translation="MSNRMILNETSYFGKGAIESIVPEFQQRGFGKAAVITDKGLIEH
                     GIATKVTELLDKAAIAYALYDGIVPNPTIQNVKDGVAFVKEAEADCLIAIGGGSPIDT
                     AKAIGIILTNPEFSDVISLEGVADTKNPCLPILAIPTTSGTAAEVTINYVITDEVNHR
                     KFVCVDPHDIPIVAFIDSDMMMGMPKKLAASTGMDAMTHAIEGFITKGAWEMTDMLHL
                     KAIEIIGHSLEASVDGDQNGREKMALGQYIAGMGFSNVGLGLVHGMAHPLSAWYNIPH
                     GVACAALLPTVMKYNKEYTGEKYREIALVLGIKGAAEMSLEDVREAACGEIDRLSKAV
                     GIPETISELGVKEADIPAIAEDALRDVCTPGNPRETTVEEIIALYQSLM"
     gene            complement(12521..12832)
                     /gene="rhaM"
                     /locus_tag="LLC22_001823"
     CDS             complement(12521..12832)
                     /gene="rhaM"
                     /locus_tag="LLC22_001823"
                     /EC_number="5.1.3.32"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose mutarotase"
                     /protein_id="HBK5435101.1"
                     /translation="MVKKAFCMKVYPEKQEEYKKRHDELWPEMRTALREHGVIDYSIY
                     LDPSTSLLFGYLVIEDEKLWEKMANTSINQKWWKYMEDIMETNPDASPVSWELMPVFE
                     L"
     gene            complement(12834..13679)
                     /gene="rhaD"
                     /locus_tag="LLC22_001824"
     CDS             complement(12834..13679)
                     /gene="rhaD"
                     /locus_tag="LLC22_001824"
                     /EC_number="4.1.2.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulose-1-phosphate aldolase"
                     /protein_id="HBK5435102.1"
                     /translation="MKKIDILQAPYVKEMIETTSNLYRLGWDERNGGNISYLLKEEEI
                     TPFLDPEKVIRRISMIFDASRLAGCYFIVTGSGRYFKNVASEPAENLGIVRVAEDGKT
                     LELLWGLENECLPTSELPSHFMSHIARLEVDPDNRIVMHCHASHLLAMSFTHELDERS
                     FSRTLWQMCTECLVVFPEGISIIPWMVPGTNEIGEATAEKMKETRLVLWPQHGIYGSG
                     KDMDEVFGLIETAEKAAEVYTYVKAQGPILQTITDENLWHLADAFGVTPKAGYLEEVH
                     TKAGV"
     gene            complement(13693..14949)
                     /gene="rhaA"
                     /locus_tag="LLC22_001825"
     CDS             complement(13693..14949)
                     /gene="rhaA"
                     /locus_tag="LLC22_001825"
                     /EC_number="5.3.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345777.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-rhamnose isomerase"
                     /protein_id="HBK5435103.1"
                     /translation="MNTIERNYEQAKEKYATIGVDTDAVLEKIQDIKISMHCWQGDDV
                     KGFLTPDGELTGGIMATGNFPGAARTPEELRQDLEKAYSLIPGKHKLNLHAIYLDTEE
                     SVDLNEIEPKHFEKWVEWAKKEEIGLDFNPTFFSHPMMKDGFTLAHPDKEVREYWIEH
                     GKRSRKIAEYFGKETGQTSINNFWVPDGMKDNPIDRFTPRERLMESLDEIFTEELDER
                     YVQDAVESKLFGLGAEAYTVGSHEFYMGYGLTRDKLVCLDAGHFHPTEVISNKLSSLA
                     LFSKGIMLHVSRPVRWDSDHVVLMDDELQEIAKELVRNELLEKTNIGLDFFDATINRI
                     AAWVIGTRNTQKALLKAMLEPVERLKEMELAFDFTSRMAYTEELKDFPYADVWNYFCY
                     KNQVPVGLDWLEEVQEYQKDVLELRK"
     gene            complement(14946..16406)
                     /gene="rhaB"
                     /locus_tag="LLC22_001826"
     CDS             complement(14946..16406)
                     /gene="rhaB"
                     /locus_tag="LLC22_001826"
                     /EC_number="2.7.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rhamnulokinase"
                     /protein_id="HBK5435104.1"
                     /translation="MNPTFVAIDIGASSGRLMKSTRDAKGSLILEEVHRFKNGFRNKD
                     GHDRWKIDYLIKEILIGFEKLKQTGIDRLFAGIDTWAVDYCLIDEQGDRINDPIAYRD
                     KRTNGAVEQFSEIYSLDKLYEQTGIQIQPFNTLFQLFAEEKENLAKAHKLLLIPDYLG
                     YVFTGNMVTEKTNASTMQLLNAGTKEWEIELLEKIGVSKELFPPLTEPGTILGDLQKE
                     QFSKYDLPDVTFITVASHDTASAVLGTPGQGERWGYISSGTWSLLGIETKIANVSRNA
                     FSENYTNEWGAHNTVRFLKNIMGMWLIQEVARMQEYEYSYAELAELAAKEKPLQQVME
                     INDPRFLNPPNMIEEIQQYCFETEQPVPVSSGAIARCVYDNLALCYAQELIKVEHLTG
                     TKLEKLHIVGGGSNNRLLNQLTADYAGIIVEAGPSEATAIGNVAMQMLSTGQFSNIEQ
                     ARNVIKQSFPCETFYPDENKQNTMEWYVNKIKGVIV"
     gene            16559..17428
                     /locus_tag="LLC22_001827"
     CDS             16559..17428
                     /locus_tag="LLC22_001827"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309732.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family ligand binding domain-containing
                     protein"
                     /protein_id="HBK5435105.1"
                     /translation="MDYWEKANHSWSEDSKRVILTPTQRSRNLFFYIQEIGYFKAPIP
                     YYTERAHLPSYLIKFTLSGKGSLTYNDNQQQLKAGDLFFIDCQEYQRYQTISEEPWEM
                     DWIHLNGQNVQSFYQEFTKDGHNTFHSTGDPSENKIHHLITELIHMQQGTNARTDFQS
                     SVAIHELLNELILQKYQLDFEEEDIPAYVYKLKQYLDEHFKETITLDQLEQQFLLNKY
                     QLSKDFSKFIGSPPIDYLISKKLSYAKDLLRYTEFTVRMISEEIGIENFAYFSRLFKA
                     KTGLSPRDFRKFS"
     gene            complement(17554..18453)
                     /locus_tag="LLC22_001828"
     CDS             complement(17554..18453)
                     /locus_tag="LLC22_001828"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435106.1"
                     /translation="MLQKKISGEQVNTMVSDQYEIYHVKDVVSQNKTIYHHHDFYEIH
                     ATLKGEATFYLNGRQFTIKAGSVLLIHSNDLHRIVRQSSDVFERVYIFVTPSFLESRS
                     TPWSNLSACFQPMGEKRSRVLQIEQEVLKQKLSFIDHPPDKKIYGEDIKYEQALVEYL
                     IFLNQVVQKEESAQEQNAVVPNERVEQMLQYISKNLSHPLSLEEMEKQFFVSKYHITR
                     EFKKYTGFTFHQYVMKKKLIYAKHLLREYRSSSAVYSKSGFSSYPHFLKAFKREFGIT
                     PKEFLKRDTQKQLVHYEHFEDEQ"
     gene            complement(18618..19442)
                     /locus_tag="LLC22_001829"
     CDS             complement(18618..19442)
                     /locus_tag="LLC22_001829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar phosphate isomerase/epimerase"
                     /protein_id="HBK5435107.1"
                     /translation="MLNITIRGHDLSEVQTIEDLAEKTKEQGIHTLQLALGLSFPEIP
                     SGANEINSGMGNYVKRVLEKQEVTVGILSCYINMIHPDLTIRQELLTKFEQYLRYASS
                     FGASMVASETGCVLPEIQYTEENFTDEAFAEAVSVIRRLVKAGEKYQMMVGIEPGLNH
                     PVYSLARVEQLIQAVDSDYLGIILDPTNLITSSDYQEQVQLVEEAFERFGEKICAVHL
                     KDFRVEQEKIVPVNLGDGVIEYTKIKEIIMKNRPYLYVVLEETKDDGIRYGRSLLE"
     gene            complement(19453..20748)
                     /locus_tag="LLC22_001830"
     CDS             complement(19453..20748)
                     /locus_tag="LLC22_001830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288256.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter large permease"
                     /protein_id="HBK5435108.1"
                     /translation="MAIEAGLVLFFVFVVLLVLGMPIAISIAFSSMMTLLLVIPFDVS
                     AFSSAQKMVGSINSFSLIAIPFFVLSGIIMNNGGIAKKLVDFAMLFVGRVPGALAHTN
                     VLGNALFGSISSSAIAASTAIGGVLIPQQVEEGYDRKFATAVNIASAPTGMVIPPSTA
                     FIMYSLVAGGASISALFMGGYLVGALWALGIMLVAFIVAKKNKYPVVEKGQMAHAGKI
                     IKEAIPSLLLIVIIIGGILTGIFTAVEASAIAVIYSLLIAMFYYKTVKLKDIPNMLFQ
                     SVAMSGTIMFLLATSSMMSFAMAFTGIPQAISSLIMGVTDNKFIILLLVNLVLLLVGM
                     FMDVAPAILIFTPIFLPIVTSVGVDPVHYGLFSIMNLCVGSITPPVGTGLYVGASVGG
                     VKAEAMLKPLLPFYGVILVVLFLITYFPQIVMWLPNMLS"
     gene            complement(20764..21243)
                     /locus_tag="LLC22_001831"
     CDS             complement(20764..21243)
                     /locus_tag="LLC22_001831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293392.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter small permease"
                     /protein_id="HBK5435109.1"
                     /translation="MKMILNKVLEILGAVLLVGMVAVVLWQVFSRTVLGNPNTVTEEL
                     VRFGLVWFAMLSSAYVVGQKAHLAVTVLSEKLTGKKSKILEVVVQSLFLVFAAMIMVY
                     GGWNAVTLTMGQISPSLSIPMGYVYLSVPVSGVLIIIYSLINLIDTLSNKPAIQEKI"
     gene            complement(21249..22277)
                     /locus_tag="LLC22_001832"
     CDS             complement(21249..22277)
                     /locus_tag="LLC22_001832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TRAP transporter substrate-binding protein"
                     /protein_id="HBK5435110.1"
                     /translation="MKKTSLLFAASSLSLGLLGLSGCGNNSSVATVADADVNEIVTLR
                     FAYASNSQPVIDAMNEFGRLVKEKTDGSVQIQYFPDGQLGGERELIELTQSGAVDFTK
                     VSASALESFSKDYSIFSVPYLFNDEEHFFKVMDNEEIMEPIYQSTKNLGFTGLTYYDS
                     GQRSFYMVDGPIHTPEDLKGKKIRVMQSETAIKMVELLGGSPVPMGSDEVYTSLQSNL
                     INGSENNEFVLYTAGHGGVAKYYSYDEHTRVPDIIIMNDAIKEQLTDEQEKAIEEAAK
                     ESTVFEIEAFAKAIEEEKALAQEEHGVQFNDVDNTPFREAVAPLHDIFKNDPTYKDLY
                     QKIQEQGA"
     gene            complement(22294..23400)
                     /locus_tag="LLC22_001833"
     CDS             complement(22294..23400)
                     /locus_tag="LLC22_001833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBK5435111.1"
                     /translation="MIIKEEIFVPKELVKEKIDLLVENLTTIKDDNGEFLLDFDGLKV
                     DDKSWTVWNWPQGVGLYGIYKNYQMTKNPRAYQVVNEWFEDRMEEGAPPKNVNTMAPL
                     LTMAYLYEDTKDSRYLPYLEQWAEWVMNDMPRTNEDGLQHATYGPENKNQLWDDTLMM
                     TVLPLAKIGKLLNRPEYLEEARYQFMIHIKYLMDKRTGLWYHGWTFEGNHNYAEAFWA
                     RGNCWLTIAIPEIIEILELSKEDALRKLLIETLEAQVRALKTYQSESGLWHTLLDDPS
                     SYVESSATAGFAYGILKAVHKRYLPQEYKEVAYRAIQGLLEQIDEKGEVQNVSIGTGM
                     GDSLDFYRNIGITAMPYGQSLTVLCLTELLVSYC"
BASE COUNT         6779 a         5200 c         4239 g         7358 t
ORIGIN      
        1 cccgcttctt tgctatacta aagaaaaacg aggtgaaccc acatgaaaaa aatcgaacct
       61 attccacctt ctcttcctct tcttacaaag ggagagtttt atttagaaga tgaggagatc
      121 ttctctggtc ttctgatcaa cgggggtgac caaagctatc tcgatgccaa aaatatggta
      181 ttaagagaga gtcatatcca aaaacttacg atgcaaaaaa cagttttacg tcattttgaa
      241 tgcagtaatg tcatttttga aaaatgtgat ttttccaatc tggagtggat tggtggcagt
      301 ttccaccaag tcgtgtttca tcaatgtaaa ttaacaggta cgaattttgc cgaaagttat
      361 cttcgagact gtactttcac tgattgtatt gcttcgatgg cttcctttag tagtacaaac
      421 ttgaaagctg tctccttcga tcattgtcaa ttagaagaca gcgaatttta tgaggtcact
      481 tggaaaaacc tttttttgtc tgacaatcag ttgaccggtt cgaactggtt tcgaacttct
      541 ctgaagggat tagactttac gactaatttc ttcacagcaa tcgctttatc tcaagattct
      601 ttggcgggac taatcgtcaa ccaagagcaa gcacttgtga tcgcccaagc ccttggtttg
      661 cagatcaaag actagatcaa cgaatccgcc gccacagtgc aataagcatc caaatagata
      721 agaccaaact gatgatcaag gcgattcccc atccgaaaac ggaatgggta aagggtaact
      781 ggagattcat tccgaagaat cctgtcacaa tagttggaac ggtcaagatc agcgaccaga
      841 ccgtcaaaaa tttcatcgtg tcattcaagt tgttattcag caaattatta taagtgccag
      901 agagctggtc taaaatctgc gaagctaagt tcgtcatttc aactgcttgt cgtgcttcga
      961 tcagcgcatc gtccaactct tctttttcct tttctgacaa cttgcgataa atagccaatg
     1021 ccttgatttg ttctaaaagt actacatttt gttttgttcc tgtaactaag taaaccaaac
     1081 cgatctctaa atctgaaagt tgcagcagat tcttgttcgt tgttttttct cttaatttca
     1141 gattaagccg ctgacgttca ctattcactt cctcgattaa aggaaaaaag gaatcagaaa
     1201 tcaaaaacaa tgtacgaaac aataaactgt atacactcat gtctggcatt cgttccaaaa
     1261 gcgatcgaat tagtcgaatc acgtactcgg tattcggcgt ggtaaatgta aacaaaccgt
     1321 cttcttttaa aataaaagcg ataggactag tttcataatg attatcgact ttttgctggt
     1381 gcggaacatt tgatacaagc agtaacgctt catcaaaaga atcgtactct acgcgcgccc
     1441 gttcattttt atctagagaa taagtcagca tctcgtcact aatgccatat tcttctttta
     1501 agtttttaac agctagcaca tcgttttgct gtacattgat ccaaaaatta cggtcttgat
     1561 taaaatagtg tttttcccgc atactctatc ctcctgacat ttgtttccag tataaagaaa
     1621 aaagtcgctc aaataaaggt ttacccttta tttgagcaac tgtaaatcaa atggctactt
     1681 tggtttggcg aatctctgct aatttttctt cgatcatttt caagacttct tcttttgctt
     1741 gaggatcttc cacaaaatta tagcggtctc catcgatttg gatttttgga ctttctttgt
     1801 attcttcata ccattgatcg taacgtctgt tcaattcttt gtaataatcg tatagacttg
     1861 gatcaaagga caattgttca tacgaacgac cacgtttttc gatacgctcc aacatcgtat
     1921 caaaagatac acgaatatga actaataaat ccggatgttt tttatgggca gcatagggaa
     1981 gttcttccat catgttttcc agcagttcat catacacacg aacttctgtt tctgttgctc
     2041 ttcctagatc tgcatttaga tggaaaagca gtgaatcttc ataaatcgaa cggtccaata
     2101 cattattgtc atctttcatt gcttgtttga tgcttgcaaa acgtttattc aaaaaataaa
     2161 tttgcagcaa aaaagcatac tgttcagggt ttgcataaaa taagggcaag acttcattat
     2221 catcaatcga ttcataaaat gcctgactat caaagtgttc agccatcatt tctgttaaac
     2281 ttgattttcc ggcaccaatt gtacctgcta aaacgatcac gctcatttac ctccagctca
     2341 cttcatcact aaatattgtg tttaactcca acctttttaa atataccccc aatatctagt
     2401 agtgtcaatt gtattttttt ctagtcaaag aagaaaaaaa gtcaaaaaat tcttaagaaa
     2461 aaagtgtttt ttctttagaa aacgtattct tagttttact tctgagatgg ttttagtaaa
     2521 ataaaggagg aatgtttttt gagaccctta gtggacaaaa aaattcgtga agcagcgcaa
     2581 ctcgttttgg gcgctttatt ttttgcttaa aaatcacttt tacgtgagaa ggagttagat
     2641 tatggcaaac tatggccaag gagaatcaag cggaaagatc atattgatgg gcgagcacgc
     2701 ggttgtttat ggagaaccag cgattgcctt tcctttctat gcaacaaaag tcaccgcatt
     2761 ccttgaagag ctggatgcaa tggacgatca actggtttct tcctactatt caggaaattt
     2821 agccgaagct cctcatgcat taaaaaatat caaaaaatta ttcattcact taaaaaaaca
     2881 gcatgacatc caaaaaaact tgcaactgac cattgaaagc acgattcctg ctgaacgtgg
     2941 aatgggatca agcgctgcag tcgccacagc agtcactcgt gctttttatg attacttagc
     3001 atttcctttg tctcgtgaaa tactattaga aaatgtccag ctttcggaaa aaatcgccca
     3061 cggtaatcct agtggaatcg atgcagccgc tactagcagc ttgcagccga tttattttac
     3121 aaaagggcat cctttcgact acttttcttt gaacatcgat gcttttttga ttgtcgctga
     3181 tacaggaatc aaaggacaaa caagagaagc cgtcaaagat gtcgctcacc tctttgaaac
     3241 ccagcctcat gaaactggac aaatgatcca aaaattagga tacttgacga agcaagcaaa
     3301 acaagcaatc attgaaaatt caccagaaac gttggcacag acaatggatg aatcacaatc
     3361 acttctggaa aagctgacaa tcagcaatga ttttcttaat ctattgatcc aaacagcaaa
     3421 agataccggg gcattgggtg ccaaattaac tggcggtgga cgcggtggct gtatgattgc
     3481 attagcacaa acaaaaacaa aagcccaaga aatcagtcaa gcacttgaag atgcgggtgc
     3541 tgctgaaact tggatacaag gattaggagt acatacctat gtttaaaggc aaagcacgcg
     3601 catataccaa cattgctcta atcaaatatt ggggtaagaa aaatgaagaa ctcatccttc
     3661 caatgaacaa cagcctttcg ttaacattgg atgcatttta tacagagaca gaagtcatct
     3721 tttctgatag ctatatggta gatgaatttt atctagatgg caccttgcaa gacgaaaaag
     3781 caacaaaaaa agtcagtcag tttcttgacc tttttcgtaa agaagccggc ctctcactaa
     3841 aagcttcagt aatcagtcag aatttcgttc ctaccgcagc tggattagcc tcctctgcca
     3901 gcgggctagc tgctttagca ggcgcttgca atactgctct taagcttgga ttagatgatc
     3961 tctctctttc aagatttgct cgacgcgggt ctggttcagc ttgccgaagt attttcggtg
     4021 gtttcgtcga atgggaaaaa ggccatgacg acttaagttc ttacgctaag ccagtccctt
     4081 ccgattcttt cgaagacgat ttagcaatgg ttttcgtttt gatcaacgac cagaaaaaag
     4141 aagtgtccag cagaaatggg atgcgtcgga cagtcgaaac atccagtttt tatcaaggct
     4201 ggttagattc cgttgaaggg gatctatatc aattgaaaca agcaatcaaa acaaaagatt
     4261 tccaacttct cggagaaacg atggaaagaa acggactaaa aatgcatgga acgactttag
     4321 ctgcccagcc tccattcact tactggtctc ctgacagctt aaaagcgatg gatgcggtgc
     4381 gacaattgag aaagcaaggc attccatgct actttacgat ggatgctggc cctaatgtca
     4441 aagttttagt ggaaaacagc catttatctg aggtacaaga aacatttacc aaattattta
     4501 gcaaagaaca agtaattact gcacatgctg gtccaggaat tgcgattatt gaataaaggg
     4561 agatttttat gattgaagta tctgcaccag gcaaactcta tattgccgga gaatatgcag
     4621 ttgttgaaac aggccatcca gcagttatcg ctgcagtcga tcaattcgtg acagtcactg
     4681 tagaatctgc acgaaaagtc ggaagtatcc aatctgcaca atatagtggg atgcctgtac
     4741 gttggacaag acgcaacgga gaattagttt tagatattcg ggaaaatcct tttcattata
     4801 tccttgctgc tattcgcttg actgaaaagt atgcacaaga aaaaaacatt cttttatcct
     4861 tttatgatct gaaagtaaca agtgagttag acagttcaaa tggccggaaa tatggattgg
     4921 gttctagcgg tgccgtgacc gttgcaacgg tcaaagcctt gaatgttttt tacgcgttga
     4981 atttatctca gttggagatt ttcaagattg cagcactagc caatttagca gttcaagata
     5041 atggttcctg cggcgacatc gctgctagct gttatggtgg ctggatcgct ttctcaacct
     5101 tcgaccatcc ttggctccaa gaacaagaaa ctcagcattc tatcagtgag ttacttgccc
     5161 tggattggcc aggtctatcc attgagccat tgattgctcc tgaagattta cgtttattga
     5221 ttggttggac gggtagccct gcctctactt ctgatttggt cgatcaagtt caccgttcga
     5281 gagaagataa aatggtggct tatcagcttt tcttaaaaaa tagtacagaa tgtgtcaacg
     5341 aaatgatcaa agggtttaaa gaaaataatg taacgttgat ccaacagatg attcgaaaaa
     5401 accgacaatt actgcatgat ttatctgcaa tcactggggt cgtcatcgaa acgcctgctt
     5461 tgaacaaatt gtgtaattta gctgaacagt atgaaggagc cgcaaaatct tctggtgcag
     5521 gtgggggcga ttgcggaatc gtaattgttg accagaaatc tggcattctt cctttaatga
     5581 gtgcatggga aaaagcagaa atcactccac tgccgttaca tgtctatagc gatcaaagaa
     5641 aggaaaaccg atgaatcgaa aagacgaaca tgtttcacta gctaaagcct ttcatgataa
     5701 acaaaaaaac gaatttgact tcgtacggat catccataac cctttgccgc aaatagcagt
     5761 ttctgatgtc gatctaagta cacaggcagt tgggtttaca ctaagcagcc cattttatat
     5821 caatgcgatg actggcggaa gcgaaaaaac aaaaaaaatc aaccaagatc ttgcaatcgt
     5881 cgcaagagaa gcagatttga tgattgccac tggttcagtc agcgctgcct tgaaagtccc
     5941 ttctttagcc gatacttata cgattatgcg acaagaatat cctcacggga aaatcattgc
     6001 caacatcggt gcagggactt ctgtcgaaag agccaaagaa gctatccgat tgtttcacgc
     6061 agatgcctta cagattcatt tgaatgcacc tcaagagttg gttatgcctg agggagaccg
     6121 tgattttacc aattggaaag tacttattca agaaactcaa acagccattg acgtccccct
     6181 catcgtaaaa gaagtcggtt ttggcatgac aagagaaacg ctcaatgatc tagctgcttt
     6241 aggagttcat acagttgata tcagcggtcg aagcggaaca agcttcaccc agatcgaaaa
     6301 cgcccgtcgc tccaagcggg aactgagtta tttagctgac tgggggcaat cgacagtctc
     6361 ttcattgctt gaagcaaatg aagcagacac ttctatggaa atcctagcct ccggaggtat
     6421 ccgcaatgcc tatgacatat ttaaagccct ttgtctcggc gcaaatgccg tgggtacttc
     6481 aggaaccgta ctgacgcatc tgatgaatca cggcgtagaa gaaactatta tactgatgaa
     6541 gcaatggcaa gaagagcttc gtctgcttta tactatggtc ggcgcaacga ataccgcggc
     6601 cctacaccaa caatctctga tcttttccgg accagtgaag gattggtgcg aagcaagagg
     6661 gatcgactta gtgaagtatg gaagacgcac agaaaagagc gtgggacaaa agtaaagaac
     6721 acttttgtct cacgctctaa acacgtacaa acggcggaag taaaagcaac tccttcggaa
     6781 ataagctgaa attcacaaaa atttgaaaag caattttcgt gaattccttc ttatttcttg
     6841 gagttaaatg cttctgtccc agcctctttt ttcgaataaa tgatgtttaa tcagctgtcc
     6901 ttcggtattc gttcaatccg ctgatttcac aacctctcca ctaaacagtg tactaaagct
     6961 cttttaaggt tgttttccga tataggcaag tatgcctccg tccacataca agacatggcc
     7021 gttaacgaaa tcagatgcgc tagaagccaa gaagacagat ggtccagcca aatcgattgg
     7081 ctcgccccag cgtgctgctg gcgtacgtcc aacgataaat tgatcgaatg gatgacgttc
     7141 accgttttct tgtgtttcgc gtaatggagc agtttgcggt gtagcaatat aacctggtcc
     7201 aattccatta cattggatat tgtattgacc gtattcagaa gcgatgtttt tcgtcagcat
     7261 ttttaatccg ccttttgccg cagcataagc actgaccgtt tcgcgtccta attcactcat
     7321 catggagcag atattgatga ttttaccgcc gcctttttcg atcatatccg gaataactgc
     7381 ttttgaaacg atgaatgggg catttaaatc cacgtcgatt acttggcgga agtctgccgc
     7441 atccatttcg atcatcggtg tccgtttgat gatccctgca ttgttgacta gaatatcaac
     7501 tgaacctaca tcttctttga tctgttgaac catcgcttga accgcttctt catcggtcac
     7561 atcgcagaca taaccttttg catcgatgcc tgcttcttta taatgcgcta taccttcatc
     7621 aactgattct tgattcaagt tattaaatac gatttttgct cctgctgtag ctaaagagcg
     7681 tgcaatctca aatccaatac catagacagc accggtgact aatgctactt ttccatctaa
     7741 acgaaacata tccatactaa attccatcat tttctctccc ttatgcttat tttaattgat
     7801 ccatttgcac catatccatg tctgtatagg tgatattttc tccgcacatt gcccagatga
     7861 atgagtaatt gcttgtacct acacctgaat ggatcgacca gcttggcgaa ataatggctt
     7921 gttcattgtc tacaactaaa tgttttgttt catctggttt gcccatcatg tggaacacac
     7981 gtgtatcttc attggcataa tcaaagtaga cataagcttc catacgacgt tcatgtgtat
     8041 gacaaggcat cgtattccaa gcgcttcctg gttctaaaat cgtataaccc atttgtaatt
     8101 gacagctttc gcatacattt ggatggatgt attggtagat tttacgttca ttcagtgtca
     8161 ggccttcacc agtctccatt ggttttactt ggtcgatact gatttttaca tttggatatt
     8221 tatgatgagc tggaacagaa ctaatataga atttagctgg gttttcagca tcttgagaag
     8281 aaaatacaac atgtcgtgtt tcttttccga tatagtatcc gtcttgtttt ttcatttctt
     8341 ctttttgccc atcgatctcg atgaatcctg gtccaccgat attgatcaca cctagttcac
     8401 gacgctctaa gaagtaatca acacctagtt ctttgtctaa tgtgatttct aattcttttt
     8461 cagtaggtgt cactccacca aagatcattc gatcgttgtg cgtataagtc aaactgattt
     8521 tccctggttc aaataccttt tctactaaaa attcttttct caattgttcc gttgaataat
     8581 gacggatatc ttctggactg tgtgtataac gtgtttccat ttcttgcatt ttcttctact
     8641 ccttctatcg aatgattttt ccagagccgc atgctaaaaa ttgtgcgact tcttcttgac
     8701 taaattggtt gcagtcccca tggatcgtat gcttcaaggc agaagctgcc gtagcaaaat
     8761 caatgatttc ttgcggagac atattggata aaatcccatg gagcacgcca cctgcaaaag
     8821 catctccgcc acctactcga tccacgattg gggtgattct atggacttgg gattccacat
     8881 attcatggtt catccacaat gtccccttca attcattttc acttgctgaa tgaacggtac
     8941 gcttggtcga ataaaacacc tgaatattcg ggaacttttc ctgcattttt tgataataat
     9001 aaattagagg ttgttcttct gcttctggcg ctttctcgat acctaacaaa taaagagcat
     9061 ccatttttcc agctgagcag atatctacta aaggtaaaag ctgatggatt acttcgctgg
     9121 cttcttgctg tgtccataat tttccacgat agttgatatc gaagctgatc aggcagccag
     9181 ctttttttgc agcttctatc acctgtttcg tcattttttg ccatttttta gacaaagctg
     9241 gggtgattcc tgaaacatga aatatatcta ttccttggaa taactcctct agcgaccatt
     9301 ccaaatgatc catttcagca aaacttgatc cggcacgatc atagatcact gaggcggcgc
     9361 gttcgccact accagtttcc atataataag tacctagtct tgatccacca gataatacct
     9421 gtttcgtatc tactccataa cattgcaagt gctttttgac tgcttttccc aatgcgttat
     9481 caggtacttt tgtagcaaaa atcgcttcat gtccgtaatt agctaaagaa attgctacgt
     9541 ttgcttcccc tccgccataa tgggcagcga atcgttcact tgaatcgata cgggttccct
     9601 gctctgtgga caatcgcaac atgatttctc cgagtgtcac tacttttccc ataagcagct
     9661 acctcttgat ttctttcatt tttgctgcat actgttgcgc gacttccgtt actttgtcaa
     9721 aatctcctgt agctgcgggt gctaaaaggt tcccacctac tccgactgtt acgacaccag
     9781 catcgaacca ctctttcata ttgtccagac tcacaccgcc agttggcatg atattgactt
     9841 gaggcatcgg cgccttgaag gcagaaatga tacttggtcc ataagcgctt ccaggaaata
     9901 gtttgacgat atctaccccg cttttcagcg ctgttttgat ctcggtaata gtcatacatc
     9961 ctggtaagta aggaatttga tacagattgc acatctctgc cgtttcttga tcaaaggaag
    10021 ggctaacaat atactctgcg ccagctaaga tagccaagcg agctgtgaca gcgtctaata
    10081 ctgtgcctgc gccaatcact atttctggtt ggtctttgta gaatgacaaa agttctttga
    10141 ttacttgatc tgcttgaggg actgtaaaag tcaactcaat accagttaga ccacctttga
    10201 tgattgcgtg gcaagcattc aaagcttctt ctttgctttt tccgcgtacc accgcaatca
    10261 ctccggcgtt tttcaatcga gataaaatat caattttttt catcttctcc acctatttcc
    10321 tatttagaaa ttttatttta taacttggaa atctataccc atattatacg gcagaaaaga
    10381 aaaattgcaa acgctttttt cattattttt gaattctttg ctcgatttcg ctttttgttt
    10441 gcttgagggc actgattatt tgttcttttg tctcatctgt taaacgatat ttcggcatac
    10501 ttacactaaa tgcaccaatg atttgttcgt ttttcacgat tgaggctcct atacaaaaaa
    10561 tatcacgttc gatttcttca tcgtcaaatg cgatgtgggt ttcttttacc gtttggattt
    10621 cctttttcaa ccgtaatgca ttggtgatcg tatattctgt gtaagggatc aacggatgct
    10681 tttcaagata atcagtgtac tgctcttcac tgaattctgc taatacggct ttgcccatcg
    10741 cagaattgta taatggtcgg gtgattccga tttttgaaga catgcggatc gtttgatgtt
    10801 ttggatctag tttgttcacg tacaagatct cattgttgtc caatacccct aagtggatag
    10861 tctcatcgat cttttgctgc agctgttcta aaaacggtaa agtcaactct accaaatcga
    10921 tttgttcaat gtttttattc gcgtagcgaa taagctttgc acctaaacga tagtttttct
    10981 ctgaattttt atttacgtag ccgatcatca acaaagtatc tagtattttc aagactgtag
    11041 aagaggtcat tcccacaccc tttgcgatcg tctgcaaaga gacatcttgg ttttccgcta
    11101 aatagtctag tattttagag gctttgatca atacagttcc ataaggcttt ttattttcca
    11161 tataatattc tcctatttct ttataagaaa aattatagcg gaaataccat caatttaaaa
    11221 gagatatcca gatataaact accatttctc tttacaggca atttaatgtt gaagatccgc
    11281 ttcgttttta catcaaactt tgatataaag caatgatttc ttctactgtc gtttctcttg
    11341 gatttcctgg tgtgcataca tctcgcaaag catcttctgc aattgctgga atatctgctt
    11401 cttttacacc taattcagaa atggtttctg ggattccaac cgctttgctc aaccgatcga
    11461 tctcaccaca agccgcttct cttacatctt ctaaagacat ttcagctgct cctttaatcc
    11521 ctagaacaag agcgatctca cggtactttt ctccagtata ttctttgtta tatttcatga
    11581 cagttggcaa aagtgctgca cacgctacgc catgaggaat gttgtaccat gcacttaacg
    11641 ggtgagccat cccgtgtacc agtcctaaac cgacatttga gaagcccatt cccgcaatat
    11701 actgtcctaa tgccattttt tctcgcccat tttgatcgcc atctacagaa gcttccaaag
    11761 aatggccgat gatttcgatt gcttttaaat gcagcatatc agtcatttcc caagcgcctt
    11821 ttgtgataaa cccttcaata gcatgcgtca tagcatccat acctgttgat gcagccaatt
    11881 ttttcggcat tcccatcatc atatcgctgt cgatgaacgc gacgattggg atatcatgag
    11941 gatcaacaca aacaaatttt cggtgattta cttcatctgt gatgacgtag ttgatcgtta
    12001 cttctgctgc tgttccagaa gtcgttggta tagctaatat aggtaaacat ggatttttcg
    12061 tatcagcaac accttctaaa ctaatgacgt ctgaaaactc tggattcgtc aaaataatcc
    12121 caatggcttt tgccgtatcg attggcgaac ctccaccgat tgcgatcaaa cagtctgcct
    12181 ctgcctcttt aacaaaagcc actccatctt ttacattttg gatcgttgga ttaggtacga
    12241 tcccgtcgta taaagcataa gcgattgctg ctttatctag aagttctgtt acttttgttg
    12301 ctataccgtg ctcgatcaat cctttgtcag taatgacagc tgctttgccg aatcctcgct
    12361 gctgaaattc agggacgatc gactcaatcg ctccttttcc aaaatacgat gtttcattta
    12421 aaatcattcg attactcatt ttctattcct cctaatttgt attatttttc acaataaaaa
    12481 cgaaagaacc ccaagcaacc ggttgcccag ttgcttgttg ctacagttca aagactggca
    12541 tcaattccca actgactgga gaggcatctg gatttgtctc catgatatct tccatgtact
    12601 tccaccattt ttgattgata gatgtatttg ccattttttc ccataacttt tcatcttcga
    12661 tcactaagta accaaataac aaacttgtac tcggatcaag atagatcgaa tagtcgatga
    12721 ccccgtgttc acgaagtgct gtacgcattt ctggccaaag ttcatcatgt ctttttttgt
    12781 attcttcttg tttttctggg taaactttca tgcaaaaagc ttttttcacc atgtcagaca
    12841 cctgctttcg tatgaacttc ctccaaataa cctgcttttg gagtgacacc aaacgcatct
    12901 gctaaatgcc acaggttttc gtccgtgatt gtttgcaaga ttggtccttg cgctttgacg
    12961 tacgtataga cttctgctgc cttttctgct gtctcgatca aaccaaagac ttcatccatg
    13021 tcttttcctg acccgtagat tccatgttgt ggccataaaa ccaatcgagt ttctttcatt
    13081 ttttcagctg ttgcttcccc aatctcattt gttcccggaa ccatccacgg aatgatggaa
    13141 attccttctg gaaaaacaac taagcattcc gtacacattt gccatagcgt acgactaaag
    13201 gaacgttcgt ctaattcatg cgtaaaactc atcgctaata gatgactagc atggcaatgc
    13261 ataacgatcc gattatctgg gtctacttct aaacgggcga tatgactcat gaaatgactt
    13321 ggcaactcgc ttgtaggaag gcattcgttt tccagccccc acaaaagttc cagtgttttg
    13381 ccatcttcag caactcgaac gattccaaga ttctcggcag gttcgctcgc tacattttta
    13441 aaatatcttc ctgaaccagt tacaataaaa tagcatcctg ctaaacggct ggcatcaaaa
    13501 atcatcgaga tgcggcggat cactttttca ggatccaaga acggtgtgat ctcttcttct
    13561 tttagtaaat aagaaatatt cccgccattt ctttcatccc atcccaagcg ataaagattc
    13621 gacgtcgttt cgatcatttc tttcacataa ggcgcttgta aaatatctat ttttttcaat
    13681 atagccacac tcctattttc ttaattccaa cacgtctttt tgatattcct ggacttcttc
    13741 cagccaatcc aaaccaactg gaacttgatt tttgtaacag aaataattcc atacatcggc
    13801 atacgggaaa tctttcaatt cttccgtata agccattctt gaagtaaagt caaaagccag
    13861 ctccatttct ttcaatcgct caactggttc cagcatagct ttcagcagtg ctttttgtgt
    13921 atttctcgta ccgatgaccc aagcagcgat acggttgatc gttgcatcaa agaaatccag
    13981 accgatattt gttttttcca acaattcgtt acggactaat tctttagcga tttcctgcaa
    14041 ttcatcatcc atcaaaacca catggtctga atcccaacgc actggacggg aaacatgcaa
    14101 catgattcct ttgctgaata aagctaatga agataattta ttggaaatca cttctgttgg
    14161 atgaaaatgt ccagcatcta gacaaacaag tttgtcacga gtcaacccgt aacccatata
    14221 aaattcatgg gaaccgactg tataagcttc agcgcctaaa ccaaatagtt tgctttctac
    14281 tgcatcttgt acataccgtt catctaactc ttctgtaaaa atttcatcga gtgattccat
    14341 taaacgttcc cgtggggtaa aacgatcaat cggattatct ttcatcccat caggtaccca
    14401 aaagttattg atacttgttt gcccagtttc tttcccaaag tactccgcga ttttgcggct
    14461 tcttttcccg tgttcgatcc agtattcacg aacttcttta tctggatgag ccaatgtaaa
    14521 gccgtctttc atcattggat gcgaaaagaa agtcggattg aagtcaagac cgatttcttc
    14581 tttttttgcc cactctaccc atttttcaaa atgtttcggc tcaatttcat ttagatcgac
    14641 agattcttct gtatccaaat agatagcatg aaggttcaat ttgtgtttgc ccggtatcaa
    14701 cgaataagcc ttctccagat cttgtctaag ctcttcaggt gttcgtgcgg ctcctggaaa
    14761 attccctgtc gccatgattc caccggtcaa ttcgccatcc ggtgtcaaga aacctttgac
    14821 atcatctcct tgccagcaat gcatagaaat tttgatgtcc tgtatctttt ctagtacagc
    14881 atctgtatct acaccgatag ttgcatattt ttcttttgct tgttcgtaat ttctttcaat
    14941 cgtgttcata cgattactcc tttgatttta ttcacgtacc attccatcgt gttttgctta
    15001 ttttcatctg ggtaaaaagt ttcacatgga aacgactgtt tgattacatt tcttgcttgt
    15061 tctatattcg aaaactgacc tgtactgagc atttgcatgg caacattccc gattgctgtg
    15121 gcttcactag gtcctgcttc tacaatgatt ccggcataat ctgctgtcaa ttgattcagt
    15181 agacgattat tcgatccgcc ccctacgatg tgcagctttt ccaatttcgt tccagttaag
    15241 tgttctactt tgatcagctc ttgtgcgtaa caaagagcaa gattatcata cacacaacga
    15301 gcgatagctc ccgatgagac agggactggc tgctctgttt caaaacagta ttgctgaatc
    15361 tcttctatca tatttggggg attcaaaaat cgagggtcat tgatttccat cacttgctgc
    15421 agcggttttt cttttgcagc aagctctgcc aattccgcat aactgtactc gtactcttgc
    15481 attcgggcaa cttcctggat caaccacatc cccatgatgt ttttcaaaaa acgcaccgtg
    15541 ttatgggcac cccattcatt cgtataattt tcagaaaaag cattgcgaga aacattggcg
    15601 atctttgttt caatccctaa aagcgaccat gtcccactgc tgatataacc ccaacgttct
    15661 ccttgacctg gcgttcctaa tacagctgac gccgtatcat gacttgctac tgtgataaag
    15721 gtcacatctg gcaaatcata ttttgaaaat tgttcttttt gcagatctcc tagtatcgtt
    15781 cccggctctg tcaatggtgg aaataattcc ttcgagacac cgattttttc aagaagttct
    15841 atttcccatt cttttgtccc tgcattcagc agctgcatag tagatgcatt agttttctcc
    15901 gtcaccatgt taccagtaaa gacataccct aaataatcag gtatcagtaa caatttatgt
    15961 gcttttgcca aattttcttt ttcttcagca aacaattgga acaaggtatt gaaaggctgg
    16021 atctgaatcc ctgtctgctc atacaactta tctagagaat agatttcaga aaactgttct
    16081 actgctccat tggtacgctt gtcccgataa gcaatcggat catttatccg atccccttgt
    16141 tcatcaatca gacagtaatc gactgcccat gtatcgatcc ccgcaaaaag gcgatcaatc
    16201 cctgtctgct ttaatttttc aaatccaatc aaaatctctt tgataagata atcgatcttc
    16261 cagcgatcgt gaccgtcttt gttccgaaag ccgtttttga accggtgtac ttcttccaag
    16321 atcaaagaac cttttgcatc cctcgtactt ttcattagtc gtccgcttga tgcaccgata
    16381 tcgatggcaa caaatgttgg attcatttct ccacctcttt tactttattg ttgattagca
    16441 ctttattaat aaagcgttat catttattaa caatgctatc ataatacaga atcttatatt
    16501 ttgcttcaca ctattttggt atataattgc attatcttga caagttggga gtgtttacat
    16561 ggattactgg gaaaaagcca accactcatg gtcggaagac tcaaaaagag tgatcttgac
    16621 gcctacacaa agaagcagga atttattttt ttatatccaa gaaatcggtt acttcaaagc
    16681 accaatccct tactatactg aacgagcaca tttaccttct tacttgataa agtttacttt
    16741 gtctggcaaa ggttcgctta catataatga taatcagcaa cagctaaaag ctggagactt
    16801 attttttatt gactgccaag aatatcagcg ttatcaaacg atcagcgaag aaccatggga
    16861 aatggattgg atccatttga atggtcagaa cgtccaatca ttttatcagg agttcacaaa
    16921 agacggccat aacaccttcc attcaacagg ggatccatca gaaaacaaga tccaccattt
    16981 gatcacagaa ttgatccaca tgcaacaagg cacgaatgcc cgtaccgatt tccagtcctc
    17041 tgtagctatc cacgagttgc tgaatgaact gattttgcaa aagtatcagc tagatttcga
    17101 agaagaggat attcccgcct acgtttacaa actgaagcaa tacttagacg aacatttcaa
    17161 agaaacgatt acacttgatc aattagaaca acaattctta ttgaataaat atcagctgag
    17221 caaagatttt tccaaattta tcggttctcc accaatcgat tatttgatca gcaaaaaact
    17281 ttcttacgct aaagaccttc ttcggtatac agaatttacg gttcgaatga tttccgaaga
    17341 aatagggatt gagaattttg cttactttag ccgcctgttc aaagcaaaaa caggactatc
    17401 gccgagagac tttcgtaaat tcagctgatt catataatat gtacgtcatt ttttcaaaat
    17461 attttgaaat atatagataa aaataaaata accgcagttt ctgcttctat gtaaacaaca
    17521 gcagctactg cggttatttt ttagtgatca ttctcattgt tcatcttcaa aatgttcata
    17581 atgaaccaac tgtttctgtg tatcacgttt caaaaattct ttaggcgtta tgccgaactc
    17641 tctcttgaat gctttcagaa aatgcggata agaagaaaaa ccacttttac tatatacagc
    17701 actagagctg cggtattctc gcaacaagtg cttggcatag atcagctttt tcttcattac
    17761 atactgatga aacgtaaatc cagtgtactt tttaaattct cgtgtgatat ggtatttgct
    17821 gacaaaaaac tgcttttcca tttcctctaa agaaagcgga tgagataaat tttttgagat
    17881 atattgtaac atttgttcca cacgctcatt aggaactaca gcattctgtt cttgcgcact
    17941 ctcttctttt tgtacaactt gattgagaaa aatcaagtat tctaccagag cttgttcata
    18001 ttttatgtct tcaccgtaaa tttttttatc aggaggatgg tcgataaatg ataatttttg
    18061 cttcaatact tcctgttcta tttgcaatac acgactcctc ttctctccca ttggttgaaa
    18121 gcaagccgat agattagacc atggcgtgga acgactttct agaaaagaag gggtgacaaa
    18181 gatatagaca cgctcgaata catctgaaga ttggcggacg atacgatgca aatcattgga
    18241 atggatgagc agcacacttc ctgctttgat cgtaaattgt cgtccgttca aataaaaagt
    18301 cgcttctccc tttaatgtag catggatctc atagaaatca tgatgatgat agatcgtttt
    18361 attttggctg acgacatctt tgacatgata gatttcatac tgatcagaaa ccatcgtatt
    18421 gacttgttca ccgctgattt tcttttggag catgtgccgc acctcctttt gttcacttat
    18481 gcacaatttt attataccac gttttttgta atcaaaaaga gctgctttta tatactctta
    18541 taaaaaagaa gagacgtggc atcttctagc cccgccccct ccattctaaa tattagttaa
    18601 ccaacgtctt ctttacatta ttcaagaaga cttcttccat aacgaatccc atcatctttt
    18661 gtttcttcaa gaaccacata caggtacgga cgattcttca tgatgatttc tttgattttt
    18721 gtgtactcga tcacaccgtc tcccaaattt accggcacga ttttttcctg ttcgacacga
    18781 aaatctttca aatgaaccgc acatatcttt tcaccaaaac gttcaaaagc ttcttctacc
    18841 aattggactt gttcttgata atcactactt gtgatcaaat tggtcggatc taaaatgatt
    18901 cctagatagt ccgaatctac tgcttggatc agctgctcta cccttgctaa agaatacacc
    18961 ggatgattca aacctggttc tatccccacc atcatttggt atttttctcc agcttttacc
    19021 aagcgacgga taacggacac agcttcagca aatgcttcat ctgtgaaatt ttcttccgta
    19081 tattggattt ccggcaaaac acatccagtt tccgaagcaa ccatcgacgc accaaaggaa
    19141 gaagcatagc gaagatactg ctcgaacttt gtcagcaact cttgtcgtat cgttaaatct
    19201 ggatgaatca tattgatata gcaacttaaa attcctacgg tcacttcttg cttttctaaa
    19261 actcgtttga cataatttcc catcccagaa ttgatctcat ttgcgccaga aggtatttca
    19321 ggaaacgaaa gacctaaggc gagctgcagt gtatgaatcc cttgttcttt tgttttttct
    19381 gcaagatctt ctatcgtttg gacttcggaa agatcatgtc ctctaattgt aatgttcaac
    19441 ataactattc tcctaactca gcatattggg tagccacatg acgatttgcg ggaagtaagt
    19501 aatcaaaaac aagacgacta agataacccc ataaaaagga agaagcggtt tcagcattgc
    19561 ctctgctttt acgcctccta cacttgcacc gacatatagt cctgtaccta ctggcggcgt
    19621 gatggagcct acacacagat tcatgattga aaacaacccg taatgtacag gatcaacccc
    19681 tacacttgtg acgattggta aaaatattgg tgtaaaaatc aagatagcag gcgccacatc
    19741 cataaacata cccaccagta ataacacaag attgactaat aacagaataa taaatttatt
    19801 atccgttacg cccataatca acgaactaat tgcctgagga ataccggtaa acgccatggc
    19861 gaaagacatc atggaagaag tagccaataa gaacatgatc gtccctgaca ttgctactga
    19921 ttgaaacaac atattaggta tatcttttag ttttaccgtt ttatagtaaa acatagcaat
    19981 caacagggag taaatgacag ctatcgctga agcttctact gctgtaaata tccccgtcaa
    20041 gataccaccg ataatgatga caatcaatag aaggctagga atcgcctctt ttattatttt
    20101 tccagcatga gccatctgtc ctttttcgac aacagggtat ttattctttt tagcaacgat
    20161 gaatgctact agcatgattc ctagcgccca caaagcgcct acgagataac ctcccataaa
    20221 caaagcagag atcgaagcac caccagcaac aagtgaatac atgataaaag cagtacttgg
    20281 aggaatgacc atacctgtcg gagctgacgc gatattgacc gctgtcgcaa acttccggtc
    20341 atatccttct tccacttgct gagggatcaa cactccgcca atcgcggtag aagcggcaat
    20401 ggccgagcta gagatggaac caaataaagc attccctaac acattcgtat gagccaaagc
    20461 ccccggcacg cgcccgacga acaacatcgc aaaatccact agtttcttag ctatccctcc
    20521 attattcatg ataatgcccg agagaacgaa aaacggaata gcgatcagcg aaaaactatt
    20581 gatacttccc accatttttt gagctgaact aaaagcagaa acatcaaacg gtataactaa
    20641 caataaagtc atcatcgatg agaatgcaat acttatagca atcggcatcc ctaatacaag
    20701 caacacaaca aatacaaaaa ataacactaa tccggcttct attgccattt tattcctcca
    20761 tttttatatt ttttcttgaa ttgctggctt gttgcttaat gtatcgatta gattgatcag
    20821 gctatagata atgatgagta cccccgatac aggtactgac agataaacat atcccatagg
    20881 aatacttaaa gaaggcgaga tctgccccat tgtcaatgtg acagcattcc atccgccata
    20941 caccatgatc atcgcagcaa ataccagaaa taaactttga acaacaactt ctaaaatttt
    21001 actttttttg ccagttaatt tttcacttaa aaccgttacg gctaaatgtg ctttttgtcc
    21061 cacaacatac gcggaagaca acatggcaaa ccagacaaga ccgaatcgaa caagctcttc
    21121 cgtgaccgta tttggatttc ctaaaaccgt tctggaaaat acttgccata aaacaacagc
    21181 gaccatccca acaagcaaaa cagctcccag gatctctaat accttgttta aaatcatttt
    21241 catcacagct acgctccttg ctcttggatc ttttgataaa ggtctttgta ggtaggatcg
    21301 tttttgaata tatcatgaag tggggcaact gcctctcgaa acggtgtatt atctacatca
    21361 ttgaattgga ctccatgttc ttcttgtgct aaagcttttt cttcttcaat tgcttttgca
    21421 aaagcttcaa tttcaaaaac cgttgattct ttcgctgctt cttcaatggc tttttcctgc
    21481 tcatcagtta gctgttcttt gatggcatca ttcatgatga tgatatctgg cacacgtgta
    21541 tgctcatcat aggaatagta tttagccaca ccaccatgtc cagctgtata caagacaaat
    21601 tcattgtttt ctgatccgtt gatcaaattg gattgaagag acgtgtacac ttcatcactt
    21661 cccataggta cgggcgaacc gcctaaaagc tctaccattt tgatagcggt ttcgctttgc
    21721 atcacacgga tcttctttcc cttcaaatct tccggcgtat ggatcggacc gtctaccata
    21781 taaaagctgc gctgaccaga atcataatag gtcaatccgg taaatcctaa atttttggtc
    21841 gattggtaga ttggctccat tatttcttca ttatccatca ccttaaagaa atgttcttca
    21901 tcattgaata gataaggaac tgaaaaaatc gaataatctt tagagaaact ttccaacgct
    21961 gaggcactta cttttgtgaa atctactgct cctgactgtg tcaattcgat cagttcacgt
    22021 tctccaccca gttgtccatc tgggaaatac tggatctgta cggaaccatc tgttttttct
    22081 tttactaaac gcccaaattc attcattgca tcaattactg gctggctgtt gcttgcataa
    22141 gcaaagcgca aggtaactat ctcatttaca tctgcatctg cgacagttgc cacactagaa
    22201 ttatttccgc agccgcttag acctagcaga cctaggctaa gcgaacttgc tgcaaacagc
    22261 agtgatgttt ttttcatatg ggtttccttt cttttaacaa taagagacga gcaattctgt
    22321 caaacaaagc accgttaacg actgtccata aggcattgct gtgattccga tattccgata
    22381 aaaatctaaa ctgtccccca ttcctgtccc gattgaaacg ttttgaactt ctcctttttc
    22441 atcgatttgt tcaagcaatc cttggatagc acgataagcg acttctttat attcttgtgg
    22501 taaataacgt ttatggaccg ctttcaaaat accgtaagca aatcctgcag ttgcagaaga
    22561 ttctacgtaa gaagaaggat catccaacaa cgtatgccat aaaccgcttt cagactgata
    22621 agtttttaat gcacgcactt gtgcttcaag tgtttcgatc aataatttgc gcaatgcatc
    22681 ttctttcgat aattctaaga tttcaatgat ctctggaata gcaatcgtca accagcagtt
    22741 tccacgagcc caaaatgctt cggcatagtt atgatttcct tcaaacgtcc agccgtgata
    22801 ccacaatcct gttcgtttat ccatcaagta tttgatatgg atcataaact ggtaacgagc
    22861 ttcttctaaa tattctgggc gattcaacag tttcccgatt tttgccaaag gaagcactgt
    22921 catcatcaat gtatcgtccc acaactgatt cttattttcc ggtccatatg tggcatgctg
    22981 taacccgtct tcatttgtcc gaggcatgtc attcatgacc cattctgccc attgttctaa
    23041 ataaggcaaa tagcgtgaat ctttcgtgtc ttcatacaag taagccatag tcaatagcgg
    23101 tgccattgta ttgacgtttt tgggcggagc gccttcttcc atacgatcct caaaccattc
    23161 attgaccact tgataagcgc gaggattttt tgtcatctgg taatttttat aaataccata
    23221 tagaccgaca ccttgtggcc aattccacac tgtccagctt ttgtcatcta ctttcagtcc
    23281 atcaaagtcc aacaaaaatt caccattatc gtctttgatc gttgtcaggt tttcaacgag
    23341 caggtcaatt ttttctttca ctaattcttt aggtacaaaa atctcttctt taataatcat
    23401 ctttacgcca cttttttaaa cgctttcatt ttatatcctt aatatagcag taataccgtc
    23461 cactataaat atcgcttttt gaacaaaaac tgtctaaaat tgacctaaat gttaaataac
    23521 aaaagtaact ttcagttact tggaaattaa aaaaagaact tggagaaaca acgttt
//
LOCUS       DAFBVQ010000042        23362 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.043, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000042 DAFBVQ010000000
VERSION     DAFBVQ010000042.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.043"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(108..179)
                     /locus_tag="LLC22_001834"
     tRNA            complement(108..179)
                     /locus_tag="LLC22_001834"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(144..146),aa:Arg,seq:ccg)
     gene            239..1573
                     /gene="rpoN"
                     /locus_tag="LLC22_001835"
     CDS             239..1573
                     /gene="rpoN"
                     /locus_tag="LLC22_001835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA polymerase factor sigma-54"
                     /protein_id="HBK5435112.1"
                     /translation="MKFEQNFSQKQQQTQKLAMTQQLQQSIQVLQYNSEELLAFVENQ
                     AMENPLVEVVEPEWQPDYIKASSSSYEGEETNYLNQIPDTKGSLFDSLIEQVHLNYRD
                     TFLRKIVLYLVEYIDLNGFLTISLEEAGKEIGATPIQMLDALTLIQQLEPAGVGARSL
                     QECLMLQTERDDYAPELAYIVLEECFEELVERKWKEIAQRFSVDLHAVQQIFDYLQTL
                     SPSPGRIFDRSSELYIIPDVRVLVDDDKNVQVISNRKNQPNIRFQESYFKQMSQQADK
                     ETENYLKERKQEFEWLKKTILQRGDTILRVAQVIVSRQKAFFIDKERPIKPLTLKEVA
                     TEIDVHESTVSRAVNGKYLETDFGVFELKKFFTTRIPTNSTEQTEDLSADTAKKKLQE
                     LVDQEDKNKPLSDQKLVELLKKDEIAISRRTVAKYRDLLGIPSSSKRKRYDN"
     gene            1722..2813
                     /locus_tag="LLC22_001836"
     CDS             1722..2813
                     /locus_tag="LLC22_001836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="central glycolytic genes regulator"
                     /protein_id="HBK5435113.1"
                     /translation="MGRFKSTLDVKCPTKEIAMLDEIKMIESVAPDIIEVLQERYKIL
                     RNIYWMQPIGRRSLSESMGITERVLRTETDLLKNLNLIDTSKSGMTLTTKGEEVYQSL
                     ENFMDQLLGTHQTEQQLAEYFGNQRCIVVSGNSEEQTKVADAFGEALSEALDRLLPEG
                     ENIIAVMGGTTMAVVAEQLSNLENKKRHNLFVPARGGIGEAITVQANSVSARMAAKAN
                     GNHRALYVPEQLSLATYNSLLNEPSIQEVLNLISEANCVIHSIGRALHMAARRKMTEK
                     ELVMLKQANAVAESFGYFFNEKGEVVYKVPRIGIELQDLEKVPIIMAIAGGKSKAKAI
                     RAYMKNAPKQTWLITDEAAANEILKGVTL"
     gene            2854..3855
                     /gene="gap"
                     /locus_tag="LLC22_001837"
     CDS             2854..3855
                     /gene="gap"
                     /locus_tag="LLC22_001837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010755973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I glyceraldehyde-3-phosphate dehydrogenase"
                     /protein_id="HBK5435114.1"
                     /translation="MTVKVGINGFGRIGRLAFRRIQDVDGIEVVAINDLTDAKMLAHL
                     LKYDTTQGRFNGTVEVHEGSFNVNGKEVKVLANRNPEELPWGELGVDIVLECTGFFTS
                     KSAAEKHLTAGAKRVVISAPGGNDVPTIVYNTNHETLTGKETVISGASCTTNCLAPMA
                     KTLNDKFGVVEGLMTTIHAYTGDQMTLDGPHPKGDFRRARAAAANIVPNSTGAAKAIG
                     LVIPELNGKLDGAAQRVPVPTGSLTELVTVLEKEVTVDEINAAMKEASNESYGYNTDE
                     IVSSDIVGMTYGSLFDATQTKVMTVGDKQLVKTVAWYDNEMSYTAQLVRTLEYFANL"
     gene            3965..5155
                     /locus_tag="LLC22_001838"
     CDS             3965..5155
                     /locus_tag="LLC22_001838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005228679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate kinase"
                     /protein_id="HBK5435115.1"
                     /translation="MAKKTVKDIDLKDKKVLVRVDFNVPLKDGVITDDTRIKAALPTI
                     NYVLEQGGKAILFSHLGRVKTEEDKEGKSLAPVAKRLGELLGKEVTFVPETRGEQLEE
                     AIRNMNDGDVVVFENTRFEDIDGKKESKNDTELGKYWASLGDVFVNDAFGTAHRAHAS
                     NVGIASTGIPTVAGFLMEKEIKFIGEAVEEPKRPMIAILGGAKVSDKIGVIENLIPKA
                     DKILIGGGMTYTFYEAKGIKIGNSLVEADKVELAKELIEKAGDKLVLPIDNVCAPEFS
                     NDVETQVIEGDIPDGLMALDIGPASVKLFADTLQGAKTVVWNGPMGVFEMSNFAKGTI
                     GVCEAIANLEGATTIIGGGDSAAAAEQLGFADKFTHISTGGGASLELLEGKELPGLAA
                     INDK"
     gene            5259..6014
                     /locus_tag="LLC22_001839"
     CDS             5259..6014
                     /locus_tag="LLC22_001839"
                     /EC_number="5.3.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878431.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triose-phosphate isomerase"
                     /protein_id="HBK5435116.1"
                     /translation="MRKPIIAGNWKMNKTASEAKEFAEAVKNKIPSNDKVDSVIGSPA
                     LFLQELMTSAEGTELKISAQNCYWENSGAFTGETSPAALADLGVHYVIIGHSERREYF
                     HETDEDINKKAKAIFANGMTPILCCGESLETYEAGKTAEWIEGQITAGLADLSAEQVS
                     NMVIAYEPIWAIGTGKSADAQIADEICGVVRQTVEKLYGKEVSEAVRIQYGGSVKPEN
                     IAEYMAKENVDGALVGGASLQADSFLSLLDAVK"
     gene            6130..7428
                     /gene="eno"
                     /locus_tag="LLC22_001840"
     CDS             6130..7428
                     /gene="eno"
                     /locus_tag="LLC22_001840"
                     /EC_number="4.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013773781.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphopyruvate hydratase"
                     /protein_id="HBK5435117.1"
                     /translation="MSIITDVYAREILDSRGNPTIEVEVYTESGAFGRGMVPSGASTG
                     EYEAVELRDGDKARYGGKGVTKAVDNVNNIIAEAIIGYDVRDQMAIDKAMIALDGTPN
                     KGKLGANAILGVSIAVARAAADYLEVPLYHYLGGFNTKVLPTPMMNIINGGSHADNSI
                     DFQEFMIMPVGAPTFKEALRMGAEVFHALASILKARGLATSVGDEGGFAPNLGSNEEG
                     FEVIIEAIEKAGYVPGKDVVLAMDAASSEFYDKEKGVYVLADSGEGEKTTDEMIKFYE
                     ELVSKYPIISIEDGLDENDWDGFKKLTDVLGDKVQLVGDDLFVTNTQKLSEGIEKGIA
                     NSILIKVNQIGTLTETFEAIEMAKEAGYTAVVSHRSGETEDSTISDIAVATNAGQIKT
                     GSLSRTDRIAKYNQLLRIEDQLGEVAEYKGLKSFYNLKNK"
     gene            7827..8966
                     /locus_tag="LLC22_001841"
     CDS             7827..8966
                     /locus_tag="LLC22_001841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314669.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgE/DapE family deacylase"
                     /protein_id="HBK5435118.1"
                     /translation="MKKEEKIAILQEIIRIKSVNGNEGEVAAYLNKLLAKHDITGEIV
                     SYRDGRDNLIARYQKGQSGKVLGLSGHMDVVAAGDESSWTYAPFAAEIHGNRLYGRGA
                     TDMKSGLAAMVIAMIELKESGKPFNGTVKLLATVGEEVGELGGEQLTKAGYVDDLDAL
                     IIGEPTNYSLMYTHMGSINYTVTSHGKEAHSSMPDQGYNAINHLNEFITKANAEMNHL
                     AETIENPVLGKTIHNVTLISGGNQVNSIPSHAQLQGNIRSIPEYPNDKIIALLQSIVN
                     ELNQETDYHLELMIDYNKIPVKADPDSPLIHCIQQQFSQPLPLVGAAATTDAAEFTKA
                     NHSFDFVVFGPGVVTLPHQVDEYVEIDNYLDMIEKYQGIILSYLA"
     gene            complement(9033..9608)
                     /locus_tag="LLC22_001842"
     CDS             complement(9033..9608)
                     /locus_tag="LLC22_001842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5435119.1"
                     /translation="MNKNKMATRVLTVMALCIGINYIGGTIALWLRLPIYLDSIGTIF
                     AGALLGPVPGMLTGLSSGILSGVTTDIFSLYYSPIQILTGLLAGLILPRYLGKDKNSL
                     KLLLLALILSVPGTIVSSIITVQLFGGITSSGSSMIVQLLHGLGLSQTTSVILVQAGT
                     DYLDRLLSIVVVSLVITMLPQRLIYSKRKIG"
     gene            complement(9613..10587)
                     /locus_tag="LLC22_001843"
     CDS             complement(9613..10587)
                     /locus_tag="LLC22_001843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="purine nucleosidase"
                     /protein_id="HBK5435120.1"
                     /translation="MRKVIIDCDPGIDDTLALSLAVKSPDIEVVAITVVCGNVPADIG
                     TQNVLKCLERCDRLDIPVYQGMEKPLKQPFISAQDTHGMDGLGETNFPMILRKQAEPL
                     HAVDFLADYFKEKTNTSVIALGPLTNIASALKVNPNIGKHMERFVSMGGTYKSHGNCS
                     PVAEYNYWCDPEAASYVFENLKQTIEMVGLDVTREIVLTPTILEYCCQMNPEEGEYLK
                     AITRFYFDFHWKQERILGCVINDPLAVAYFIEEAICEGFKSFTAVETQGISRGQTLVD
                     RYEFWQKPANSKIMTKVDTRLFFRKFLTVLLNAQEETIMKDLERLKMG"
     regulatory      complement(10611..10655)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00522"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="PreQ1 riboswitch class I; Derived by automated
                     computational analysis using gene prediction method:
                     cmsearch."
                     /bound_moiety="preQ1"
                     /db_xref="RFAM:RF00522"
     gene            10870..11838
                     /locus_tag="LLC22_001844"
     CDS             10870..11838
                     /locus_tag="LLC22_001844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268520.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5435121.1"
                     /translation="MVIFYFILILIIIGISYHFLSYFYAKKLVRAGVQRGYDWYEDTG
                     HRLMDPAAVTSVEKKRQKLEEECESFWEQGTPKTIKSYDGLKLAGQMFIHPNKQNKWV
                     ICVHDYRSTGKRDMSHIGKRYAEKGFNVLVPDLRAHGESEGEIIGMGWLDRLDLIAWI
                     QLILDEQPNASIILHGGSMGASTIMMASGEKLPSAVKGFILDSGYVSVYAEFRYMLSK
                     ITVFPKKMVMRYANHYAQKYAGYSLKQASATRQLGSNHLPLLVIHGERDHFVPTEAAY
                     TIQNATAGDKALLLVPEAEHLEASMKDPKTYWTVIFSFIEQRITMN"
     gene            11935..12228
                     /locus_tag="LLC22_001845"
     CDS             11935..12228
                     /locus_tag="LLC22_001845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015370997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBK5435122.1"
                     /translation="MRSAAYGNQRRKNRLALFNDEQQEIGEMTWSDAGPDIMIIDHTF
                     VDPAYRGQKLAEKLVYTGVELARRDGKKIIPLCPYAKKEFEKKPEYQDVLRQS"
     gene            12346..12582
                     /gene="secG"
                     /locus_tag="LLC22_001846"
     CDS             12346..12582
                     /gene="secG"
                     /locus_tag="LLC22_001846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="preprotein translocase subunit SecG"
                     /protein_id="HBK5435123.1"
                     /translation="MYNLILGIVIVLSIVMVIAIMMQPSKQNSAASAFTGGADQLFGK
                     QKARGFEAVMQRSTAVMGAIWMILLFVLAYLSSK"
     gene            12685..13440
                     /locus_tag="LLC22_001847"
     CDS             12685..13440
                     /locus_tag="LLC22_001847"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta fold hydrolase"
                     /protein_id="HBK5435124.1"
                     /translation="MRRVRQLPKPLYAKHGKRAVLLLHAYSGSPNDVRMLARFLEKAD
                     YTVYAPLFKGHGTMEPYDILQEKAESWWADTKKAIHFLQSEQFSDIAVLGLSMGGIFA
                     VRALEEESVIGGGFFCSPLSPVKTNVPENFEKYVRQVLKTAGKSEKEINEKAVAYRSL
                     AEQQLMDIQDQAAIVESRLSDIQQPIFLAQAGKDEMIDPNGVFETARKLSRQRVTLQW
                     YPESGHVITVGTARRELEKDVLEFLEKLPWNEE"
     gene            13443..15800
                     /gene="rnr"
                     /locus_tag="LLC22_001848"
     CDS             13443..15800
                     /gene="rnr"
                     /locus_tag="LLC22_001848"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease R"
                     /protein_id="HBK5435125.1"
                     /translation="MTKETIKEKILFFMESSRKRSFSMEEIAEGLGFQKSDDFKLLVQ
                     TIAQMEREQSIVFNKKGKVKLPLKPILIEGTFRANERGFGFVTIDPEEDDIYIPKEAT
                     GFAMDGDTVAIDIMKRANTDMDRGAEGKVVEIRDRATTQLAGEFVAYSEEEIQETDLY
                     GVVIPKDRKLNQFKVYAAAEGVRPVDGSIVLIELTHYPEKGYATSLEGIIKQVIGHKN
                     DPGMDILSIVVANGIPTKFPDDVLSEADEVPDQISEKDITGRRDLRNQLIVTIDGEDA
                     KDLDDAVTVKKLDNGNYFLGVHIADVSYYVTQGSQLDREAYERGTSVYLTDRVIPMIP
                     QRLSNGICSLNPHVPRLTMSCEMEIDPNGQVVSHDIFPSVIQTTERMTYTAVNQILED
                     QDEETMQRYAQLVPMFQEMGELHRILETMRIKRGAISFEDREAKILVDAEGHPNDIQL
                     RSRGIGERLIESFMLAANETVAEHYNKLNLPFIYRIHEQPKEEKMQRFFDFASALGIL
                     VRGTKGTITPKDLQHVIEGVEDKPEAAVINTMLLRSMQQARYSEDNFGHYGLAADYYT
                     HFTSPIRRYPDLIVHRLIRSYSEDKSESNQSSWAAELPEIADHSSKMERRAVETEREV
                     DSMKKAEFMMDKVGEEFDGIISSVVKFGLFIELPNTVEGLIHINELKQDYFHFVENHL
                     ALVGERTGLTFKIGQKVRVKVVKADPDERAVDFELVSAEEVTALERPKTRNGKSGKRE
                     GKQAGKRPERNGKKNKRYSDSKQTFGKKKGKKPFYKGVKKKKKKK"
     gene            15822..16286
                     /gene="smpB"
                     /locus_tag="LLC22_001849"
     CDS             15822..16286
                     /gene="smpB"
                     /locus_tag="LLC22_001849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878455.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SsrA-binding protein SmpB"
                     /protein_id="HBK5435126.1"
                     /translation="MPKGEGKLIAQNKKARHDYSIIDTMEAGMVLQGTEIKSIRNSRI
                     NLKDGFIRVRNGEAFLHNVHISPYEQGNIFNHDPLRTRKLLLHKKQIIRLENELKNTG
                     ITVVPLKVYIRNGYAKVLIGLAKGKKSYDKREDLKRKDIDRQIDRTLKNFSR"
     gene            16588..17307
                     /gene="atpB"
                     /locus_tag="LLC22_001850"
     CDS             16588..17307
                     /gene="atpB"
                     /locus_tag="LLC22_001850"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734885.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit A"
                     /protein_id="HBK5435127.1"
                     /translation="MDERSLTFHIGPIWFDGTVCIMVLLTCLIVFFLAYFFTRNLKLK
                     PTGKQNAIEWVIDFSRGIVTDNLPRKELSNFHLLAFTLFLFVFVANNIGLVTKIVLPN
                     ETTLWKSPTADPFVTLTLAFIMILLTHLFGVKKLGFKGYFVNSFLKPYSFMFPMKLIE
                     EFTNLLTLALRLYGNIYAGEVLLTLIAKMVISLGWFSLPLAIPLEMVWIAFSLFIGSI
                     QAFVFVTLSMVYMSHKIEVEE"
     gene            17360..17575
                     /gene="atpE"
                     /locus_tag="LLC22_001851"
     CDS             17360..17575
                     /gene="atpE"
                     /locus_tag="LLC22_001851"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP synthase F0 subunit C"
                     /protein_id="HBK5435128.1"
                     /translation="MNYIAAAIAIMGAAIGAGYGNGQVISKTIESMARQPEMSGQFRT
                     TMFIGVALVEAVPILGVVVALILVFGV"
     gene            17666..18190
                     /gene="atpF"
                     /locus_tag="LLC22_001852"
     CDS             17666..18190
                     /gene="atpF"
                     /locus_tag="LLC22_001852"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734887.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit B"
                     /protein_id="HBK5435129.1"
                     /translation="MLNQLAIAEVGNAMLGNVIVVSGSFLILLALLKHFAWGPISDIL
                     KKREDKIANDLDSAEQSRINSAKMEQEREQQLLASRSDAADIIKNAKESGELSRQNIL
                     KDAQEEAARLKSKAQADITVERDSALNSVKDDVAELSLQIAEKILNKELSPEMHESLI
                     NQYIEGLGSSNETR"
     gene            18177..18719
                     /locus_tag="LLC22_001853"
     CDS             18177..18719
                     /locus_tag="LLC22_001853"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit delta"
                     /protein_id="HBK5435130.1"
                     /translation="MKLDKYTVGRRYGKALFELAIDSNQAEEIYQDLVSLRQIYEQVP
                     GLGNMLSDVRLEPHEKREIMDKLVSGYDGIVKNFLEVVYAYNRMDDLLFMIEEYERRY
                     DEHQGLLLGSVTTAVPLSDEQRIQLEKNVAKTMNYQSVELKQIVDSSIIGGAIVEANH
                     RVIDGSIRTQLENMRNQLNR"
     gene            18742..20298
                     /locus_tag="LLC22_001854"
     CDS             18742..20298
                     /locus_tag="LLC22_001854"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878464.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit alpha"
                     /protein_id="HBK5435131.1"
                     /translation="MAIKAEEISALIKEQIENYQNVLSVEEIGTVTYVGDGIARAHGL
                     ENAMSGELLEFSNGSYGMAQNLESNDVGIIILGDFESIREGDKVKRTGKIMEVPVGEA
                     LIGRVVNPLGQPIDGLGEIVTDKARPVEAMAPGVMQRKSVNEPMQTGLKAIDALVPIG
                     RGQRELVIGDRKTGKTSIAIDTIINQKGQDMICIYVAIGQKDSTVRTQVETLKKYGAM
                     DYTIVVNAGASQPAPLLYIAPYAGTAMGEEFMYNGKHVLIIFDDLSKQAVAYRELSLL
                     LRRPPGREAYPGDVFYLHSRLLERAAKLSDDLGGGSMTALPFVETQAGDISAYIPTNV
                     ISITDGQIFLESDLFYAGTRPAVDAGLSVSRVGGSAQIKAMKKVAGTLRLDLASYREL
                     EAFTQFGSDLDAATQAKLNRGRRTVEILKQKLHAPLAVEKQVVILYALTHGFLDSIPV
                     DSILDFEHELFEYLDTNHSDIFETIRTTKDLPEEEALNSAIQEYKDMFLATKGNNSST
                     EDKLKSIQNA"
     gene            20312..21214
                     /locus_tag="LLC22_001855"
     CDS             20312..21214
                     /locus_tag="LLC22_001855"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit gamma"
                     /protein_id="HBK5435132.1"
                     /translation="MGASLNEIKTRIASTKKTSQITRAMQMVSASKLTKSEASSQKFQ
                     VYATKVREIVTHLTATQLNDIASENPRGDINYNSMLLSRPVKKTGYIVITADGGLVGG
                     YNSSILKQTMSILEEDHQSPDDYVMIAIGGTGADFFKARGINLAYELRNLSDQPSFDE
                     VRKIVNMATTMYQNEVFDELYVCYNHHINSLTSQFRVEKMLPISDLDPEEATTFEQEY
                     IFEPSKEEILSQLLPQYAESLIYGAIVDAKTAEHAAGMTAMKTATDNAANIIDELTVS
                     YNRARQGAITQEITEIVAGASALE"
     gene            21237..22643
                     /gene="atpD"
                     /locus_tag="LLC22_001856"
     CDS             21237..22643
                     /gene="atpD"
                     /locus_tag="LLC22_001856"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit beta"
                     /protein_id="HBK5435133.1"
                     /translation="MSSGKIVQVIGPVVDVEFSLDQSLPDINNALVVYKNDENKSKVV
                     LEAALELGDGVIRTIAMESTDGLQRGMEVIDTGKAISVPVGKETLGRVFNVLGDTIDL
                     ETPFPEDAERSEIHKKAPAFDELSTSTEILETGIKVIDLLAPYLKGGKVGLFGGAGVG
                     KTVLIQELIHNIAQEHGGISVFTGVGERTREGNDLYYEMKDSGVIEKTAMVFGQMNEP
                     PGARMRVALTGLTIAEYFRDVEGQDVLLFIDNIFRFTQAGSEVSALLGRMPSAVGYQP
                     TLATEMGQLQERITSTKKGSITSIQAIYVPADDYTDPAPATAFAHLDATTNLERKLTE
                     QGIYPAVDPLASSSSALAPEIVGEEHYKVATEVQHVLQRYRELQDIIAILGMDELSDQ
                     EKVLVSRARRVQFFLSQNFNVAEQFTGLPGSYVPVEETVKGFREILEGKYDDLPEEAF
                     RSVGRIEDVVEKAKTLGY"
     gene            22657..23079
                     /locus_tag="LLC22_001857"
     CDS             22657..23079
                     /locus_tag="LLC22_001857"
                     /EC_number="7.1.2.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="F0F1 ATP synthase subunit epsilon"
                     /protein_id="HBK5435134.1"
                     /translation="MDQYLTVNVVTPAGLVYDHHAAIVVARTTAGELGILPKHAPIIV
                     PLTIDEVRVKRTDSDTHVDWIAVNGGIMEVRDNVVSIVADSAERERDIDVSRAERAKQ
                     RAERQIEEAKAKQDTNELKRATVALHRAINRIKVSKHS"
BASE COUNT         7864 a         4237 c         4990 g         6271 t
ORIGIN      
        1 ctatacagat acaacaaaaa actgtccacc aattctcttt ggcggacagt tttcacttaa
       61 aaataaagaa gcaactattc gtaaattatg ctaaaatagc agtagaacgc gtcctgaggg
      121 aatcgaaccc ccgtctcaag aaccggaatc ttacgtgata tccactacac taaggacgca
      181 agcactggga taattgtaac taaacagata aaaaattaca aggggattgg acaaaaaaat
      241 gaaatttgag caaaattttt cacaaaaaca gcagcagaca cagaaactag ccatgacgca
      301 acagttgcaa cagtccatcc aagttttaca atataacagt gaggagctgt tggcattcgt
      361 tgagaatcaa gcaatggaaa atccattggt ggaagttgtt gagccggaat ggcagccaga
      421 ttacataaaa gcttcttcat cttcttatga aggagaagag acaaattacc taaatcagat
      481 tcctgataca aaagggtctt tatttgattc attgatcgaa caagtccatt tgaattaccg
      541 agatactttt ttgaggaaaa tcgttcttta tcttgtagaa tacatcgatt tgaacggatt
      601 tttgacgatt agtttagaag aagccggaaa agagattgga gctacgccta tccaaatgct
      661 cgatgcgttg actctgattc agcaattaga accagctgga gtaggtgcac gtagtttgca
      721 agaatgtctc atgcttcaaa cagaacgaga tgattatgcg ccggaattag cttatatcgt
      781 gttggaagaa tgttttgagg aactggtgga gcgaaaatgg aaagaaatcg cacaacgttt
      841 ttctgttgat ctacatgctg ttcagcagat attcgactat ttacaaacgt tgagtccaag
      901 ccctggccgg attttcgacc gtagcagcga attgtacatt attcctgatg tccgggtatt
      961 agtggacgac gataaaaatg tacaagttat ctcaaaccga aaaaatcagc caaatatacg
     1021 ctttcaagag agttacttca aacaaatgtc acaacaagca gataaagaaa ctgaaaatta
     1081 tttaaaagaa cggaaacagg aattcgaatg gttgaagaaa acgatcctcc aacgtgggga
     1141 tacaattttg cgggttgctc aagtcattgt ttcccggcaa aaagctttct ttatcgacaa
     1201 ggaacgtcca atcaagcctc ttacgttaaa ggaagttgca actgagatag atgtgcatga
     1261 atccacggtc agtcgtgcag tcaacgggaa atatttggaa acagatttcg gtgtatttga
     1321 attaaaaaaa tttttcacta cacgaattcc tacgaatagt acagaacaga cagaagacct
     1381 ttcagcagat acagcgaaga aaaagctgca ggaattagtc gatcaagaag acaaaaacaa
     1441 gccgttgtcg gaccagaaat tggttgaatt gctgaaaaaa gatgagatag cgatctcaag
     1501 acgaacagta gcaaaatatc gtgatttatt aggaatcccg agttcatcaa aaagaaaacg
     1561 ttatgataac taatcagtca aaagactaga aaaagtattt cactttttct agtcttttta
     1621 gttgaaaaac gagagcaaaa ctgttagact tacagtcgtg aggttgagat ttccctttat
     1681 tgatgtgaaa ttcgaatagt taatttcttt ttttatcgta tatgggtcgt tttaagtcta
     1741 cattggacgt aaagtgtcca actaaggaga tcgctatgct ggatgaaata aaaatgattg
     1801 aatctgttgc accagatatt atcgaagtgt tgcaagaacg ctataaaatt ttacgaaata
     1861 tctattggat gcagccgatt gggcgtcgaa gtttatcgga aagtatgggg atcacagaac
     1921 gagtcttacg aacagaaaca gaccttttga aaaatctgaa tttgatcgac acctcaaaaa
     1981 gcggtatgac gctgacaact aagggcgaag aagtttatca aagccttgaa aacttcatgg
     2041 atcagctttt aggtacgcat caaaccgaac aacagttggc agaatatttt ggtaaccaac
     2101 gctgtatcgt tgtttcagga aacagcgaag agcagaccaa agtggctgat gcattcggcg
     2161 aagcgctgag cgaagcctta gaccgactac ttccagaagg cgagaatatc atcgctgtga
     2221 tgggaggaac tactatggct gtggtagccg aacaattgtc taatctggaa aataagaaac
     2281 ggcataacct gtttgtccct gcaagaggcg ggattggtga agcgataact gtacaggcaa
     2341 attctgtcag tgcaagaatg gctgctaaag caaacggtaa ccaccgcgca ctttatgttc
     2401 cggaacaatt aagtctggca acttacaatt ctttactcaa tgagccatct atccaagaag
     2461 tcttaaactt gattagtgaa gcgaattgtg ttattcatag tattgggcgt gcattacaca
     2521 tggcagcacg tcgtaagatg actgaaaaag aattagtcat gctgaaacaa gcaaatgctg
     2581 ttgcggaatc ttttggctac tttttcaatg aaaaaggtga agtcgtttat aaggtcccta
     2641 gaatcggcat agaattgcaa gatttggaaa aagtcccgat catcatggca atcgcgggcg
     2701 gaaaatcaaa agctaaagca attcgagctt atatgaaaaa tgcaccaaaa caaacgtggc
     2761 tcatcactga tgaagctgct gcaaatgaga ttttaaaagg ggtaaccctt taaaataaat
     2821 atttttttga ttttcataag gaggaaatct taaatgacag ttaaagtagg tattaatggt
     2881 tttggacgta ttggacgtct agcattccgt cgtatccaag atgtagatgg aatcgaagta
     2941 gtagcaatca acgacttgac agatgctaaa atgttggcac acttgttaaa atacgacaca
     3001 actcaaggac gtttcaacgg aacagttgaa gttcatgaag gttcattcaa cgtaaacgga
     3061 aaagaagtta aagtattagc taaccgcaac ccagaagaat taccatgggg cgaactaggc
     3121 gtagatatcg ttctagaatg tactggtttc ttcacttcta aatcagcagc tgaaaaacat
     3181 ttaacagctg gtgctaaacg cgttgttatc tctgctcctg gcggaaacga tgttccaaca
     3241 atcgtttata acacaaacca cgaaacatta actggtaaag aaacagttat ctcaggtgct
     3301 tcatgtacta ctaactgttt agctcctatg gctaaaacat tgaacgacaa atttggtgtt
     3361 gttgaaggat taatgacaac tatccacgct tacacaggtg accaaatgac tctagacgga
     3421 cctcatccta aaggtgactt ccgccgtgca cgcgctgctg ctgcaaacat cgttcctaac
     3481 tcaacaggtg ctgctaaagc tatcggttta gtaattcccg aattgaacgg taaattagac
     3541 ggagctgctc aacgtgttcc tgtaccaaca ggttcattaa cagaattagt aacagttctt
     3601 gaaaaagaag taactgttga cgaaatcaat gcagcaatga aagaagcttc aaacgaatct
     3661 tacggataca acacagacga aatcgtttcc tcagatatcg ttggtatgac ttacggttca
     3721 ttatttgatg ctacacaaac taaagtaatg acagttggcg acaaacaatt agttaaaact
     3781 gttgcttggt acgacaacga aatgtcatac actgcacaat tagtacgtac tttagaatac
     3841 ttcgctaact tataagatag acaaacgtac aagtgtaaat tatagacatg tacatttaaa
     3901 agcggggaag caatcgcgct tcttccgctt tttttgataa taagtttatt caggaggaaa
     3961 taaaatggct aagaaaacag tgaaagatat cgatttaaaa gacaaaaaag ttcttgtccg
     4021 tgttgacttc aacgttcctt tgaaagacgg cgtgatcact gacgacactc gtatcaaagc
     4081 agcattgcca acaatcaact acgttctaga acaaggcgga aaagcaatcc ttttctctca
     4141 ccttggacgt gtaaaaacag aagaagataa agaaggaaaa tctttagctc cagttgcaaa
     4201 acgtctaggc gaattattag gtaaagaagt aacattcgta cctgaaactc gcggagaaca
     4261 attagaagaa gcaatccgca acatgaatga cggcgacgtt gtcgtattcg aaaatacacg
     4321 ttttgaagat attgacggta aaaaagaaag caaaaatgat acagaactag gtaaatactg
     4381 ggcttcatta ggcgatgtat ttgttaacga tgctttcggt acagctcacc gtgcacatgc
     4441 ttctaacgta ggtatcgctt caactggtat cccaacagtt gctggattct tgatggaaaa
     4501 agaaatcaag ttcatcggtg aagcagtaga agaaccaaaa cgcccaatga ttgcaatcct
     4561 tggtggcgca aaagtttctg ataaaatcgg cgtaatcgaa aacttgattc ctaaagcaga
     4621 taaaatctta atcggtggcg gaatgactta cacattctac gaagcaaaag gaatcaagat
     4681 cggtaactct ctagtagaag ctgataaagt agaactagca aaagaattaa tcgaaaaagc
     4741 aggcgacaaa cttgtcttgc caatcgacaa tgtctgtgca ccagaatttt caaatgatgt
     4801 tgaaacacaa gtaatcgaag gagacattcc tgatggtttg atggctttag acatcggccc
     4861 agcatcagta aaattatttg ctgatacatt acaaggtgca aaaacagttg tttggaacgg
     4921 acctatgggt gtatttgaaa tgagtaactt tgctaaaggt acaatcggtg tttgtgaagc
     4981 aatcgctaac ttagaaggcg caacaacaat catcggtggc ggagactcag ctgcagcagc
     5041 agaacaatta ggattcgctg acaaattcac acacatctca acaggtggtg gcgcaagctt
     5101 ggaattgctt gaaggtaaag aattaccagg actagcagca atcaacgata aataaacgac
     5161 caagtttgct caattctgac gagtaatcga tcaaaaggtg aagggagttt tcatgactcc
     5221 ctagccattt ttcaataaat taaggagtgt gttcctcaat gcgtaaacct attatcgcag
     5281 gtaactggaa aatgaacaaa actgcatcag aagcaaaaga atttgctgaa gcagtaaaaa
     5341 acaaaatccc ttcaaatgac aaagttgatt cagtcatcgg atctcctgca ttattcttac
     5401 aagaattaat gacatcagct gaaggtacag aactaaaaat ctcagcacaa aactgctact
     5461 gggaaaactc aggtgcgttc actggtgaaa cttcaccagc agctcttgct gatctaggtg
     5521 ttcattatgt gatcatcgga cattcagaac gtcgtgaata tttccatgaa acagacgaag
     5581 acatcaataa aaaagcaaaa gctatctttg caaatggtat gacaccaatc ctatgctgcg
     5641 gcgaatcttt agaaacctat gaagcaggca aaactgctga atggatcgaa ggacaaatta
     5701 cagctggttt agctgatctt tcagctgaac aagtgtcaaa catggttatt gcttatgaac
     5761 caatctgggc aatcggtact ggtaaatcag ctgacgcaca aatcgctgac gaaatttgtg
     5821 gagttgtacg tcaaacagtt gaaaaacttt atggaaaaga agtatcagaa gcagttcgta
     5881 tccaatacgg cggttctgta aaaccagaaa atattgctga atacatggca aaagaaaatg
     5941 ttgacggtgc tttagtcggt ggcgcaagct tgcaagcaga ttcattcttg tcattgttag
     6001 acgctgtaaa ataattgttg aaaatttgtg aaaaatgcaa gaaatgtttg cactaatgag
     6061 caaaattaac taaaatcgta tatgagggaa atcccttagg aaaaaacaaa ctcaaaggag
     6121 agacaaaaca tgtcaattat tactgatgtt tacgctcgcg agatcttaga ctcacgtggt
     6181 aacccaacaa tcgaagtaga agtatacaca gaaagcggag cttttggccg cggaatggtt
     6241 ccttcaggtg cttcaactgg tgaatacgaa gcagttgaat tacgtgacgg agacaaagct
     6301 cgttatggcg gtaaaggtgt aactaaagct gtcgacaacg taaacaacat cattgctgaa
     6361 gcaatcattg gctacgatgt tcgtgaccaa atggctatcg acaaagctat gatcgcttta
     6421 gacggaactc ctaacaaagg taaattaggt gcgaacgcta ttttaggtgt ttctatcgct
     6481 gttgcacgtg cagctgctga ctacctagaa gtacctttat accactacct aggcggattc
     6541 aacacaaaag tattgccaac accaatgatg aacatcatca acggcggatc acatgctgat
     6601 aactcaatcg acttccaaga attcatgatc atgcctgttg gcgctccaac attcaaagaa
     6661 gctctacgta tgggtgctga agtattccac gcattagctt caatcttgaa agctcgcgga
     6721 ttagcaactt ctgttggtga cgaaggtgga tttgctccaa accttggttc aaacgaagaa
     6781 ggttttgaag taatcatcga agcaatcgaa aaagctggct atgtacctgg taaagacgtt
     6841 gttcttgcta tggatgctgc ttcttcagaa ttctacgaca aagaaaaagg tgtttacgta
     6901 ctagctgact caggcgaagg cgaaaaaaca actgacgaaa tgatcaaatt ctacgaagaa
     6961 ttagtttcta aatatccaat catctcaatc gaagatggat tagacgaaaa cgactgggac
     7021 ggattcaaga aattaactga cgtattaggc gacaaagttc aattagttgg tgacgacttg
     7081 ttcgtaacaa acactcaaaa attatctgaa ggtatcgaaa aaggaattgc taactcaatc
     7141 cttatcaaag tgaaccaaat cggtacatta acagaaactt tcgaagctat cgaaatggct
     7201 aaagaagctg gctacacagc agttgtatct caccgttctg gtgaaacaga agattcaaca
     7261 atctctgata tcgctgttgc aacaaacgct ggccaaatca aaactggttc tctatcacgt
     7321 actgaccgta ttgctaaata caaccaatta ctacgtatcg aagaccaact tggtgaagtt
     7381 gcagaataca aaggtttgaa atctttctac aacttaaaaa acaaataatt cttttctaat
     7441 gaagatacat gatcgactat tgaaagatag tcgagtatga tcacttagtt aagtaatcga
     7501 actctctact tgctgaaata tcagcaggta gagagttttt ttgcaactag cttctgtata
     7561 tgatgtttac aaagaatggt acaagaaaag atcatccttg aaaaaggaaa gctaacaata
     7621 actagcatca tataagagct tttaaggata gaacagtaga ataggaatct atgagcaagt
     7681 cctctcgtat aaataaaata ggagggaagt agcagcatat ttttcataaa gtggctctct
     7741 ttcttcattt ttactttggt tgctcctatt tgaaaattcg agcacactca aatacaataa
     7801 aaagaaatgg caagggagag gattagatga aaaaagaaga aaaaatcgcg attttacaag
     7861 agatcatccg aattaaatca gtgaatggaa acgaaggtga agtagcagcc tatttgaata
     7921 agcttttggc aaaacatgac ataacaggag agattgtttc ttacagagat ggtagagata
     7981 atttgattgc tcgttaccaa aagggccaat caggaaaagt gttaggccta tctgggcata
     8041 tggatgtcgt ggcggctggt gatgaatcgt cttggaccta tgcacccttt gcagcagaaa
     8101 tccatgggaa ccgtttgtac ggacgtggtg ctacagatat gaagagtggc ttggcagcaa
     8161 tggtgattgc catgatcgaa ctgaaagagt caggaaaacc atttaacgga acagtcaaat
     8221 tattagccac tgtcggagaa gaagtgggtg aactaggtgg ggaacagctc acgaaagcag
     8281 gctatgtaga tgacttagat gccttgatca tcggagagcc aaccaattac agtttgatgt
     8341 atacgcacat gggatcaatc aactatacag tcacctcgca cggaaaagaa gcgcatagct
     8401 ctatgccaga ccaaggttat aatgcaatca atcacctaaa tgaattcatt acgaaagcaa
     8461 atgctgaaat gaatcacctc gctgaaacaa tcgagaatcc tgtcctagga aaaacaatcc
     8521 ataatgttac attgatcagt ggcgggaatc aagtcaacag catcccaagc catgcgcagc
     8581 tccaagggaa cattcgatcg attccagaat acccaaatga taaaatcatt gcattgctgc
     8641 aatcaatcgt caatgaattg aatcaagaga cagactatca tttggaattg atgatcgatt
     8701 acaacaaaat acctgtcaaa gctgatccag attctccttt gattcattgc attcagcaac
     8761 aattcagcca gccattacct ttagttggag cggcagcaac aacggatgca gccgaattta
     8821 cgaaagctaa ccattccttc gactttgtcg tctttgggcc tggtgtcgtt actttgcctc
     8881 atcaagtaga tgagtatgtt gaaatcgata attatttgga tatgatcgaa aaatatcaag
     8941 gaattatttt atcctactta gcgtaagatt tttttaataa atgaaaaaac agagccagat
     9001 tagcattatt ttgctaatcc agctctgttt attcagccta tttttctttt tgaatatatc
     9061 aagcgttgtg gcaacatagt gatgactaat gaaacaacga cgatagacaa caaacgatca
     9121 aggtagtctg tacctgcctg taccaagatc acacttgttg tctgacttaa acctaaccca
     9181 tgtaatagct gaacgatcat actggatcct gaggaggtga tcccgccaaa taactgaacg
     9241 gtaatgatcg aagaaacgat cgttccaggt accgacaaaa tcaaagcgag taataacagt
     9301 ttcaagctgt ttttatcttt gccgagatat cttggcaaaa tcaatccagc aagcaagcct
     9361 gtgagaattt ggattggcga ataatacaga gaaaaaatat ctgtagtcac tccacttaaa
     9421 ataccgctgg acaatcctgt cagcattcca ggtacaggcc caagcaatgc accagcaaaa
     9481 atcgttccga tagaatcgag atagattggc aaacgaagcc ataaagcaat cgttcctcca
     9541 atataattga tcccaataca caaagccatc actgtaagta cgcgagttgc cattttgttt
     9601 ttattcattt tgttagccca tctttaacct ttccaaatct ttcataatcg tttcttcttg
     9661 tgcatttaaa agaacggtta aaaactttcg gaaaaaaaga cgagtatcta cttttgtcat
     9721 aattttactg ttagcaggtt tctgccaaaa ttcataacga tcaaccaatg tttgtccacg
     9781 acttattcct tgagtttcca cagcagtgaa gcttttgaaa ccttcacaga tggcctcctc
     9841 gataaaataa gcaacagcta acggatcatt gatgacacat cctaaaattc tttcttgttt
     9901 ccagtggaag tcaaaataaa aacgagtgat cgcttttaga tactctccct cttcaggatt
     9961 catttgacag cagtattcga ggatagtcgg tgtcaagacg atttctcttg tcacatctaa
    10021 cccaaccatt tctatcgttt gtttgagatt ctcgaataca taagaagctg cttcaggatc
    10081 acaccagtaa ttgtattcag caactggcga acagttacca tggcttttgt aagttccacc
    10141 catcgagaca aaacgttcca tatgtttccc aatatttggg ttgactttca aagcagaagc
    10201 gatattggtc aaaggaccca aagcaatgac tgatgtattt gtcttttctt tgaaataatc
    10261 agccaaaaaa tcaacggcat ggagaggttc tgcctgtttt ctcaagatca tcgggaaatt
    10321 tgtttcccct aaaccatcca taccatgagt gtcttgtgca ctgatgaaag gttgcttcaa
    10381 aggtttttcc attccttgat aaacaggaat gtctaaacga tcacagcgtt ccaggcattt
    10441 cagcacattc tgcgtaccta tatctgcagg gacattccca caaactacgg taatagcaac
    10501 tacttcgata tcaggggatt tgacagctaa tgataaagct aaagtgtcgt cgatccctgg
    10561 atcgcaatca ataattactt ttcgcattat ttccaatctc ctttctttag agatacttag
    10621 ttttttattc tgggaagttt ccgaaccagt ccaagacgag cgtcttgatt ataatgcacg
    10681 aaattagtat actggctttt attgcgaatg taaatgctct cttacaagta aatctattga
    10741 ggagaacttt aagtaaatga tacaatgaaa aagaaatgga atttacgtgt gccgaaaata
    10801 aagaatccta tggatcggta cattggataa tagatagatt atagtttggc agaaagcggc
    10861 gggtgtacaa tggttatttt ttatttcatt cttattctga taattatagg gatcagttac
    10921 cattttcttt cttattttta tgcaaagaaa ttagtaagag cgggagtaca gagaggatat
    10981 gactggtatg aagacactgg tcatcgtttg atggaccctg ctgcagtcac gtcagtagaa
    11041 aaaaaacgac aaaaattaga agaagagtgt gaaagctttt gggagcaggg aacacccaaa
    11101 acaatcaaaa gttatgacgg gttgaaacta gctggtcaga tgttcatcca tccaaataag
    11161 cagaataaat gggtcatttg cgtacatgat taccgaagca cagggaaaag agacatgtct
    11221 catataggta aaagatatgc agagaaagga ttcaacgttc ttgtacctga tttacgtgcg
    11281 cacggagaaa gtgaaggaga aatcatcgga atgggatggc tagatcggct agatttaatt
    11341 gcctggatcc aactcatctt agatgaacag ccgaatgcgt ccattatttt acacggcgga
    11401 tcaatgggag cttctacgat catgatggca agtggtgaaa aacttccatc agcggtcaaa
    11461 ggatttattt tagacagcgg atatgtttct gtttatgcag aattccgata tatgttaagt
    11521 aaaatcactg tctttcctaa aaaaatggtc atgagatatg cgaatcatta tgcccagaaa
    11581 tacgccggtt actccttaaa gcaagcatca gctacgagac agcttggcag caatcatctg
    11641 cctttattag tcatccatgg tgaaagagat cattttgtcc ctacagaagc agcgtacacg
    11701 attcaaaatg ctacggcagg ggataaagca ctgctgcttg ttccggaagc agaacacttg
    11761 gaagcatcga tgaaagatcc gaaaacctat tggacagtga ttttttcatt tattgaacaa
    11821 agaataacga tgaattaatt ttctcttctt ttttgtaagt aattcgagga taaataattg
    11881 tttatagatc aggagactgc taaaataagg taggaataaa aaaatatcag ttatttgagg
    11941 agtgcggcat atggaaatca aagaagaaaa aatcgtcttg ctttattcaa tgatgaacaa
    12001 caagagatcg gagaaatgac atggtcagat gcgggcccag acatcatgat cattgaccat
    12061 acatttgtag atccagcata tcgtggtcaa aagttagctg aaaagctagt gtatactgga
    12121 gtagaattag caagacgaga cgggaaaaag atcattcctt tatgccctta tgcaaaaaaa
    12181 gagtttgaaa agaaaccaga atatcaagac gtcttacgtc agtcataaga ataacagctg
    12241 aaagttttga actttcagct gttattccat ttatatagag ttgtcacgga cttttatcta
    12301 tgataaagtt aaagagacga tatcttttgg gaaggaggct gcgatatgta taatttaatt
    12361 ttgggaatcg tgatcgtttt atcgattgtt atggtcattg cgattatgat gcagccaagc
    12421 aagcaaaata gtgcagcgag tgcatttacc ggcggtgcgg atcaactatt cggcaaacaa
    12481 aaagctcgcg gctttgaagc tgtcatgcag cgatcaactg cagttatggg agctatctgg
    12541 atgatcttat tatttgtcct agcatattta tcttcgaagt agttgaataa gcctctcgca
    12601 aaacggcggg cggctttttt tattgcaaag agaacgctta agaagaagtt atgaaagaaa
    12661 ctatggtaaa atgaggcgaa agaggtgaga cgagtgagac aattaccaaa acccctttat
    12721 gcaaaacatg gaaagcgagc ggttttgctg cttcacgctt actcaggaag tccaaacgat
    12781 gttcgaatgc tcgcacgatt tttggaaaaa gcagattata cagtttatgc gccgcttttt
    12841 aaaggacacg gaacaatgga gccatatgat atcttgcaag aaaaagcaga aagctggtgg
    12901 gcagacacta aaaaagccat ccatttttta cagtctgagc agttttctga tattgccgta
    12961 ttaggattat caatgggcgg catctttgct gtacgagcac tagaagaaga atcagtgatt
    13021 ggcggcggtt ttttctgttc gcctttgtct cctgtaaaaa caaacgtgcc tgaaaacttt
    13081 gaaaaatacg tacgtcaagt gctgaagaca gcaggtaaat cagagaaaga aatcaatgaa
    13141 aaagcagttg cttaccgctc gttagctgaa caacaattaa tggatataca agatcaggca
    13201 gcaatcgtag aaagtaggtt gtcagatatc caacagccga tatttttagc tcaagctggg
    13261 aaagatgaaa tgatcgaccc taatggcgta tttgaaactg cacgcaagtt gagccgtcag
    13321 cgagtgacac ttcaatggta tcctgaaagt ggtcatgtga ttacagttgg tacagcaaga
    13381 cgcgaattag aaaaagacgt cttggaattt ttagaaaaat taccttggaa tgaggaataa
    13441 atatgacaaa agaaacgata aaagagaaaa ttctcttttt catggaaagc agtcgcaaac
    13501 gcagtttttc tatggaagaa atcgctgaag gtttagggtt ccaaaaaagc gatgatttta
    13561 aattactagt acaaacgatt gctcaaatgg aaagagaaca gagtatagtt ttcaataaaa
    13621 aaggaaaagt gaaacttcct ttaaaaccaa tcttgatcga aggaacattt cgagcaaatg
    13681 aacgaggatt tggatttgta acgattgatc ccgaagaaga tgacatctat atcccaaaag
    13741 aagcgactgg ttttgcaatg gatggagaca ccgtagcaat cgatatcatg aagcgagcaa
    13801 atacagatat ggatcgcgga gcagagggga aagtagtcga gattcgagac cgggcgacta
    13861 ctcagttagc aggggaattc gttgcttatt cagaagaaga aatacaagaa acagatcttt
    13921 acggcgttgt tatcccgaaa gatagaaagc tcaaccaatt taaagtatat gcagcagcag
    13981 agggagttcg tccagttgac ggaagtattg tgctgatcga actgacccat taccctgaaa
    14041 aagggtatgc gactagttta gaagggataa tcaagcaagt gattggtcat aagaatgacc
    14101 ctggcatgga tatcctctca attgtcgtgg ctaatggtat ccctacgaaa tttcctgatg
    14161 atgtattgtc tgaagcagat gaagttccag atcaaatcag cgaaaaggat ataactggac
    14221 gtagagattt aagaaatcag ctcattgtta cgattgatgg agaagatgca aaagatctag
    14281 atgatgcagt tacggttaaa aaattagata acggtaatta ttttcttgga gtacacattg
    14341 cagatgtttc ttactatgtg acacaaggca gtcaattgga cagagaagca tatgaaagag
    14401 ggacaagtgt atatttgact gatcgagtaa ttccgatgat cccgcaacgt ttatcgaatg
    14461 gtatctgttc actgaatccc catgttccaa ggctgaccat gagttgcgaa atggagattg
    14521 atccaaatgg acaagtagtc tctcatgata ttttcccaag tgtgatccaa acaacagaac
    14581 ggatgaccta cacagctgtc aatcaaatct tagaagatca agacgaagaa acgatgcaac
    14641 gctatgctca gctcgtacct atgttccaag aaatgggtga attgcaccga atccttgaaa
    14701 cgatgcgaat caaacgtggc gcgatttctt ttgaggatcg cgaagcgaaa atccttgttg
    14761 atgctgaagg acacccaaat gacatccagc taagaagcag aggaattggt gaacgcttga
    14821 tcgaatcttt catgcttgcg gccaatgaaa cggtagctga acattataat aaattaaatc
    14881 tgccgtttat ttaccgaata catgaacagc caaaagaaga aaaaatgcag cgcttctttg
    14941 attttgcttc agctttgggc attctggtcc gaggaacgaa aggaacgatc acaccaaaag
    15001 atttacagca tgtgatcgaa ggagtagaag acaaaccaga agctgcagtt atcaatacta
    15061 tgttgctaag aagcatgcaa caagcacgct attcagaaga caattttggg cattatggct
    15121 tagcggcaga ttactacaca cactttacat ctcctattcg acgctatccc gatctaatcg
    15181 tccatcgtct gatccgttct tacagtgaag ataaaagtga aagcaatcaa agttcgtggg
    15241 ctgcggaact tcctgaaatt gcagatcata gttctaagat ggaacgtcgt gcagtagaaa
    15301 cagaacgtga agtagattcc atgaagaaag cagaattcat gatggacaaa gtgggagaag
    15361 aattcgatgg gatcatcagc tctgttgtga aattcggcct gtttatcgaa ctgccgaata
    15421 cagtagaggg attgatccat atcaatgaat tgaaacagga ctacttccat tttgttgaaa
    15481 atcatttagc tcttgtaggt gaaagaactg gtctgacttt taaaatcgga cagaaagtgc
    15541 gagtaaaagt agtcaaagct gatccagatg aacgagcagt agattttgaa cttgtttccg
    15601 cagaagaggt tacagcgttg gaacggccaa aaacacgaaa tggaaaatca ggaaaacgcg
    15661 aaggaaaaca agcaggaaaa cgcccagaaa gaaatggcaa gaagaacaaa cgatatagcg
    15721 atagtaagca aacgttcggt aagaaaaaag ggaagaagcc attttacaaa ggtgttaaaa
    15781 aaaagaaaaa gaaaaaataa aatgagttgg aggaaacagc tatgccaaaa ggcgagggaa
    15841 aattaattgc acaaaacaag aaagctcgcc atgattattc gatcatcgac acgatggaag
    15901 cagggatggt cttgcaagga accgagatca agtcgatacg aaacagccgg atcaatctaa
    15961 aagatggatt tattcgcgtc cgcaacggag aagctttctt gcataatgtt catatcagtc
    16021 cttatgaaca aggaaatatt tttaatcatg atccgttgcg cacgagaaag ttattattac
    16081 acaaaaaaca aatcatccgg cttgaaaatg aattgaaaaa tactggaatc actgttgttc
    16141 ctttaaaagt ctatattcgt aacggctatg ccaaggtatt gattggtctg gcgaaaggga
    16201 aaaaatctta tgataaacgg gaagatttga aacgaaaaga tatcgatcga caaattgatc
    16261 gaacattaaa aaatttctct agataatttc attatccttt ttcgcatatt cggtgctttt
    16321 gcttttactt aatgataaaa tttgttagca tttaatctga taaaacatga ttatcatagg
    16381 ttttttctta gatcaggagc accgtgtata aagaaaaatt cgcttcgttt ttgactgaaa
    16441 taaaaaagtg tctaattttc atgaaaatgt tttgaatttt ctgtttcatg gtggtatgat
    16501 accgtgtggt tagaaaccga ttggaaaaaa ccagatacgc acatgaattg attttatgtg
    16561 aatttcgggg aaaagaggtg aaatggattg gatgaacgct cgctaacgtt ccacattgga
    16621 ccaatttggt ttgatggtac agtttgtata atggtgttac tgacctgttt gattgttttc
    16681 ttcttagctt acttttttac aagaaatctt aagttgaaac caacaggcaa acaaaatgcg
    16741 atagaatggg tcattgattt tagtcgagga atcgtaacag ataatctgcc tagaaaagaa
    16801 ttgagcaatt tccatttgtt ggcatttaca ttgtttttat ttgtttttgt tgcaaacaac
    16861 atcggtttag taacaaaaat cgttttacct aacgaaacaa cactttggaa aagcccgaca
    16921 gcagacccgt ttgttacttt aactttggca tttataatga tcttacttac tcacttattt
    16981 ggggtgaaaa agttaggctt caaaggatat ttcgtaaatt cgttcttgaa accatatagt
    17041 tttatgtttc cgatgaaact gattgaagaa tttacaaact tattaacact tgctttacgt
    17101 ctttatggga atatttatgc gggggaagtt ttgctaacct tgattgcaaa aatggtaata
    17161 agcttaggct ggttctcatt gccgttagca attccattag agatggtctg gatcgcattc
    17221 tccttgttta tcggaagcat ccaagcattt gtcttcgtta ctttatctat ggtttatatg
    17281 agccataaga ttgaagtgga agaataatat tcgttttaaa aacaaactac tatttatcta
    17341 atttaggagg aaaacaatta tgaattatat cgcagcagca atcgcaatca tgggagcagc
    17401 aatcggagcc ggttatggta acggtcaagt tatctctaaa acaatcgaat caatggctcg
    17461 ccaacctgaa atgtctggtc aattccgtac aacaatgttt atcggggtag ctctagtcga
    17521 agctgttcct atcttagggg tagttgtcgc cttgattcta gtttttggtg tttaattgaa
    17581 tcagtattaa ggcagaaaca atttggtttg ttactgcttt tttacatgaa aactagaagt
    17641 acttcaaaga aaggaaggct cgcctatgct gaatcaattg gcaattgcag aagttggcaa
    17701 tgcgatgtta ggaaatgtca tcgttgtcag cggctcattt ttgatactac tggctctctt
    17761 gaagcatttt gcttggggac caatcagcga tattttgaaa aaacgtgaag acaagatcgc
    17821 caatgatttg gattctgcag aacaatctcg catcaactca gcgaaaatgg aacaagaacg
    17881 cgaacaacaa ttgttagcct ctcgttctga tgcagctgat atcatcaaaa atgcgaaaga
    17941 aagtggagaa ttaagccgcc aaaatatttt gaaggatgct caagaagaag cagctcgtct
    18001 aaaaagtaaa gcccaagctg atatcactgt agaacgtgat tcagcgctga actctgtaaa
    18061 agacgatgtt gcagaactat ctcttcaaat cgcggaaaaa atcttgaaca aagaattatc
    18121 tccagaaatg cacgaatcat taatcaatca atatatcgaa ggtctaggtt cttcaaatga
    18181 aactagataa atatacagta ggaagacgtt acgggaaagc tttatttgaa ctggcgatcg
    18241 attcaaatca agcagaagaa atctatcaag atctcgtaag cttacgtcaa atctatgaac
    18301 aagtacctgg attaggtaat atgttaagtg atgttcgtct agaacctcat gaaaaacgag
    18361 aaatcatgga caagcttgtt agtggctatg atggaatcgt taaaaacttt ttagaagttg
    18421 tttatgcgta taaccgaatg gatgatcttt tgttcatgat cgaagaatat gaacgtcgat
    18481 atgatgaaca tcaaggtttg ctgttgggaa gtgtcacaac agcagttcca ctttcagacg
    18541 aacaacgaat acaattagaa aagaatgttg caaaaacaat gaactatcaa tcagtcgaat
    18601 taaaacaaat cgttgattct tctattattg gtggcgcgat tgttgaagct aaccatcgag
    18661 taatcgacgg aagcattcgc acgcaattag aaaatatgcg taatcaatta aatagatagt
    18721 acaaagaggt aggtgaatcg aatggccatc aaagcagaag aaattagtgc cttgattaaa
    18781 gaacaaattg aaaattatca aaacgtgctt tcagtcgaag aaatcggtac cgtaacttat
    18841 gtaggtgacg ggatcgctcg tgcacatggt ttagaaaacg cgatgagtgg tgagttgctt
    18901 gaattttcaa atggctcata cggaatggcg caaaacttag aatcaaatga tgtaggtatc
    18961 attatccttg gcgatttcga gtccattcgt gaaggagata aagtaaaacg aacaggaaag
    19021 atcatggaag ttccagttgg agaggccttg atcggacggg tagttaatcc gctaggtcag
    19081 ccaatcgacg gactaggtga aatcgttact gacaaagctc gtccagtaga agcaatggca
    19141 ccaggcgtta tgcaacgtaa atctgttaac gaaccaatgc aaacaggtct aaaagcaatc
    19201 gacgctcttg taccaatcgg acgtggccaa cgtgaattag ttatcggtga ccgtaaaaca
    19261 gggaaaactt ctattgcgat cgatacgatc atcaaccaaa aaggtcaaga tatgatctgt
    19321 atctatgtag caatcggaca aaaagattct acagttcgta cacaagttga aacattgaaa
    19381 aaatatggcg caatggatta cacaatcgtt gtgaatgccg gtgcgtctca accagcgccg
    19441 ttgctttata tcgcaccata tgctggtact gcaatgggtg aagagttcat gtacaacggt
    19501 aaacatgtct tgatcatttt tgatgatctt tcaaaacaag ctgttgctta tcgtgaactt
    19561 tccttgctac ttcgccgtcc accaggtcgt gaagcttatc caggggatgt tttctactta
    19621 cactcacgct tattggaacg tgcagcaaaa ttaagtgatg atttaggtgg cggttcaatg
    19681 actgccttac catttgttga aacacaagct ggagatatct ctgcttatat cccaacaaac
    19741 gttatttcga tcactgatgg acaaatcttc ttagaaagcg acttgttcta cgcaggtact
    19801 cgtccagcgg ttgatgccgg actatctgta tctcgtgtag ggggttctgc gcaaatcaaa
    19861 gcaatgaaaa aagttgctgg gactttacgt ctagacttag caagttaccg tgaattagaa
    19921 gcatttacac aattcggttc tgacttggat gcagcaacac aagcaaaact aaatcgtgga
    19981 cgccgtacag tagaaatctt gaaacaaaaa ttgcatgcac cgctagctgt tgaaaaacaa
    20041 gtagtgattt tgtatgcttt gacacatgga ttcttagata gtatccctgt agacagtatt
    20101 ttagacttcg aacatgaatt attcgaatat ctggatacca atcattcaga tatctttgaa
    20161 acaatccgta caacaaaaga tcttccagaa gaagaagcgt tgaacagtgc gattcaggaa
    20221 tataaagaca tgttcttagc tacaaaagga aataattcct ctacagaaga taaattgaaa
    20281 tccattcaaa atgcatagtg aggtgagatg aatgggtgct tcattaaatg aaatcaagac
    20341 acgtatcgct tcaacgaaaa aaacgagcca aatcacgcgg gcaatgcaga tggtgtctgc
    20401 ttctaagttg acaaaatctg aagcttcttc acagaagttt caggtttatg caacaaaagt
    20461 aagagaaatc gttacgcatt tgactgctac tcagttaaat gatattgcct cagaaaatcc
    20521 tagaggggat atcaattaca acagcatgct gctcagccgt cctgttaaga aaactggtta
    20581 tatcgtcatc actgcagatg gcggtttagt cggtggatat aacagctcga tattgaaaca
    20641 aacgatgtct attttagaag aagaccacca atcacccgat gattacgtga tgatcgcaat
    20701 tggcggaact ggtgcagact tctttaaagc acgcggtatc aatctagcat atgagctgcg
    20761 caatctatct gatcagccaa gctttgatga agtccgcaaa atcgtaaata tggcaacaac
    20821 tatgtaccaa aacgaagtat tcgatgaatt atacgtatgt tataaccatc atatcaattc
    20881 gctaactagt cagtttcgtg tagaaaaaat gctgccaatc tcagacttag atccagaaga
    20941 agcaactact ttcgaacaag aatatatttt tgaaccttca aaagaagaaa tcttgtctca
    21001 gttattgcct cagtatgctg aaagtttgat ctacggtgcg atcgttgacg ccaaaacagc
    21061 agaacatgct gctggtatga cagcaatgaa aacagcaact gataatgctg ctaatatcat
    21121 tgatgagctg acggtttctt ataaccgtgc aagacaaggg gctattaccc aagaaattac
    21181 cgaaattgtt gccggagctt cggcactaga atagtattga gattggagga aaaaagatga
    21241 gttcaggcaa gattgttcaa gtaatcggtc ccgttgtcga cgtggaattt tctttagacc
    21301 aatccttacc agatatcaac aacgcattag ttgtttataa aaatgacgaa aataaatcaa
    21361 aagttgttct tgaagcagcg ttagaattag gggacggagt gatccggacc attgcgatgg
    21421 aatcaacaga tggtttacaa agaggaatgg aagtcattga tacaggcaaa gcaatctctg
    21481 ttcctgtagg taaagaaaca ttaggtcgcg tattcaacgt actaggagat acgatcgatt
    21541 tagaaacacc tttcccagaa gatgcggaaa gaagcgaaat tcataaaaaa gcaccagcct
    21601 ttgacgaatt aagtacaagt acagaaattt tggaaacagg gatcaaagtt atcgatttgc
    21661 ttgccccata tttaaaaggt gggaaagtcg gactattcgg tggtgccggt gttggtaaaa
    21721 ccgtactgat ccaagaactg atccataata tcgcccaaga acatggtggt atttctgtat
    21781 ttactggtgt aggtgaacgt actcgtgaag gtaatgactt gtattatgaa atgaaagatt
    21841 caggagttat cgaaaaaaca gccatggtgt tcggacaaat gaacgaacca ccaggtgcac
    21901 gtatgcgtgt tgctttgact ggtttgacga ttgcggaata tttccgtgat gtagaaggtc
    21961 aagatgtact gttgtttatc gacaacattt tccgtttcac tcaagctgga tctgaagtat
    22021 cagccttgtt aggacggatg ccttctgcgg ttggttatca accaacattg gcaacagaaa
    22081 tgggtcaatt gcaagaacgt atcacatcta cgaaaaaagg ttcgatcaca tcgatccaag
    22141 caatctatgt gccagccgat gactacactg acccggcgcc ggcaacagca ttcgcccatt
    22201 tggatgcgac aaccaacttg gaacgtaaat taacagaaca agggatttat ccagcggtag
    22261 atccattggc ttcttcttca agtgctttag cacctgaaat cgtgggagaa gaacattata
    22321 aagtagcaac agaagtccaa cacgtattgc aacgatatcg tgaattacaa gatatcattg
    22381 ctatcttagg tatggatgaa ttatccgatc aagaaaaagt gttagtttct cgtgcccgca
    22441 gagtccaatt cttcttgtca caaaacttta acgtggctga acaatttact ggtcttccag
    22501 gttcatatgt ccctgtagaa gaaacagtga aaggattccg cgaaatcttg gaaggcaaat
    22561 acgatgatct tcctgaagaa gctttccgaa gtgttggccg aatcgaagac gtcgtagaaa
    22621 aagcgaaaac actaggctac tagaaagggg tgccccatgg atcaatattt aacagtaaat
    22681 gtggtaactc ctgccggttt ggtctatgat caccatgcag ctatcgtcgt tgcacgtacg
    22741 acagctggtg agcttgggat tttgcctaaa catgcaccaa tcatcgttcc attgacgatt
    22801 gatgaagttc gtgtaaaacg aacagattca gatacccacg tcgattggat cgctgttaat
    22861 ggcggaatca tggaagttcg tgataatgtt gtttcaatcg ttgctgatag tgcggaacgt
    22921 gaacgtgata tcgatgtatc tcgtgcggaa cgtgcaaaac aacgcgcaga acgccaaatc
    22981 gaagaagcaa aagcaaaaca agatacgaac gaattgaaac gggcaactgt tgcgttgcac
    23041 cgagcaatca atcgtatcaa agtatctaag cactcataaa atgagatgcg gatgtttatc
    23101 cgtgtttaag aacagtaaaa agaggttatg acagaagtgg tcagcttcaa gacataagaa
    23161 ggaatttacg aaaattgctt ctcaaatttt tgtgaaatct cagcttattt ttcgaagaag
    23221 ctacttctgg aacaccgtat atcagaggtt gtaaaatcag cgttttgtcc tgagtattag
    23281 agaaacaaat ggaaaagagt tcctcatatt ttgccgtttt ttgagctaat accgagggtc
    23341 agatgattga acaccgttta tt
//
LOCUS       DAFBVQ010000043        23256 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.044, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000043 DAFBVQ010000000
VERSION     DAFBVQ010000043.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23256)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23256)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23256
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.044"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(46..1977)
                     /locus_tag="LLC22_001858"
     CDS             complement(46..1977)
                     /locus_tag="LLC22_001858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400270.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5435135.1"
                     /translation="MNIKDLMVKEAMIMDLQATDKKGAIDEMVQKMFDAGRISDIETY
                     KEGILAREAQTSTGLGDGIAMPHAKNSAVKEATVLFAKSQKGVDYEALDGQPTYLFFM
                     IAAPEGANDTHLQALAALSRLLIDADFVGKLKEANTPEEVQDLFQTAEEQKEAEEKAE
                     QETQAAEASAHPERKFVVAVTACPTGIAHTYMAEDALKKKAKEMGVEIKVETNGSEGI
                     KNRLTAEDIARAEGVIVAADKKVEMNRFDGKELINRPVSDGIRKPEELINLALSGTAP
                     VFHGDGKESSSEEGNADGTIGQRIYKDLMNGVSHMLPFVIGGGIAIALSFMIDQFIGV
                     PHDQLSNLGNYNQAASWFNQIGQAAFGFMLPVLAGFIASSIGDRPGLIVGFAAGALAN
                     TGGAGFLGALIGGFLAGYVIVFLRKLFKNLPKSLDGIKTILFYPVFGLLITGFLMLLV
                     NVPMKAINDALNGFLTSMSGSNAALLGALLAGMMAADLGGPINKAAYVFGTATLATTV
                     ATGGSVVMASVMAGGMVPPLAIFVATRLFKNKFSKTDQDAGLTNIVMGLSFVTEGSIP
                     FAAADPIRAIPSFIIGSALTGGLVGAFGIKLLAPHGGIFVVFLLSHPVMYLVFIAIGA
                     VVSGVIYGLLRKAPAVAEA"
     gene            complement(1995..2909)
                     /gene="pfkB"
                     /locus_tag="LLC22_001859"
     CDS             complement(1995..2909)
                     /gene="pfkB"
                     /locus_tag="LLC22_001859"
                     /EC_number="2.7.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1-phosphofructokinase"
                     /protein_id="HBK5435136.1"
                     /translation="MIYTVTLNPSIDYIVRVDGLKLGDLNRMKEDFKLPGGKGINVSR
                     ILKRIDSQSTALGFLGGFTGEFISKWLEKEQIQSLFTTVKEDTRINIKLKSDTETEIN
                     GLGPSISDEEIDELKQALGTVGQGDIVVLSGSAPASLRKGFYQELIDIIREKGADFVI
                     DTTGDDLKNALVKKPLLIKPNNHELAELYNTTFQSVEEIIPYGKKLLAEGAQNVLISM
                     AGDGALLFTEQGTYKTNVLVRPLKNSVGAGDSMIAGFIGAYSRTKDPIEAFKWGVACG
                     SATAFSDDLAARELIDELLPEVEITKID"
     gene            complement(2906..3658)
                     /locus_tag="LLC22_001860"
     CDS             complement(2906..3658)
                     /locus_tag="LLC22_001860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5435137.1"
                     /translation="MLTEERRQKILDLLEQQKIVKSQDLVNLLNASESTIRRDLQELE
                     NSGFLERVHGGAKKEQLLNFEQNMSEKSLKNVHEKQQIAKSAAETINDEDVIYLDAGS
                     TTLEMIPFLQGKQITVVTNSVQHAANLVDLELATIILGGTIKLATNAVLGSNAIEQLK
                     NFHFNKAFMGMNGAHLEQGFTTPDPEEAAVKRLAMKNSEETFVLIDHTKFNQLSFTSV
                     APLEAATIITERCPLEFVNEFREKTTIKEAIQ"
     gene            complement(3817..4026)
                     /locus_tag="LLC22_001861"
     CDS             complement(3817..4026)
                     /locus_tag="LLC22_001861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294422.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435138.1"
                     /translation="MDKQLYYRIMVPASLLSVCLFFVPNFPIRSVIGFLVMFGGMGLY
                     YYLLHKERKPASVYMKKTRSENKKR"
     gene            complement(4037..5365)
                     /locus_tag="LLC22_001862"
     CDS             complement(4037..5365)
                     /locus_tag="LLC22_001862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435139.1"
                     /translation="MIGEDKLLMTIQLTDLNEEEKKQEISDWAILTRLLIQPTFIRSF
                     TQQADPYDLRKLQEKIMLASVRDESWLVVGNDENECSFRLEDNQLLIKNVLSISVFKE
                     KQFLIRDFIQKKMIAHGVFAYMRAYSEFIYHNTKQISQRLLFEKKDEIEHLPKMKQQN
                     GEVVVDCNQFPGYDLFYQGLCFTSCWEMYYSRYYHQIIPKPIFLDIQQVEKVKELENE
                     VICIQLYRDPFNWQKPNNQMFQSYFRDQLGFDHLAWDNGVGLLKPPFVEYIYTDHTIQ
                     SVQYQNAQMQPVPKKNASFFVTKSYDIQQGDYKERRVRGTLNAQAYFPWVDENRSRMM
                     CYKVIDPTVALDNGIEAYCYYIREYLEVEVTDEKYQEYLLSLRIYVPSESLSELPLKE
                     IKHRLSDVTFKRIKKKRRSIQFDVKKGEQHLRVQFLDYRELEQLITLQKI"
     gene            5501..5656
                     /locus_tag="LLC22_001863"
     CDS             5501..5656
                     /locus_tag="LLC22_001863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435140.1"
                     /translation="MGLKFERTDNLDKLFESFAVDPEKTVAPKEEIDRFLKPQPQNEK
                     KKDKKQK"
     gene            complement(5730..6317)
                     /locus_tag="LLC22_001864"
     CDS             complement(5730..6317)
                     /locus_tag="LLC22_001864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihA family ribosome biogenesis GTP-binding
                     protein"
                     /protein_id="HBK5435141.1"
                     /translation="MKVHQAEIIISAVAPKQYPDTQLPEIALAGRSNVGKSSFINTLI
                     DRKNLARTSGKPGKTQTLNFYLIENALHFVDVPGYGYAKVSKTERAKWGKMIETYLTT
                     RDQLRAVVSLVDLRHKPSQEDIQMYQFLKYYDIPVIVVATKADKIPRGKWNKHESEIK
                     KALDFDRNDTFILFSSVTKQGKEEAWAAIEQAIES"
     gene            complement(6400..7650)
                     /gene="clpX"
                     /locus_tag="LLC22_001865"
     CDS             complement(6400..7650)
                     /gene="clpX"
                     /locus_tag="LLC22_001865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit
                     ClpX"
                     /protein_id="HBK5435142.1"
                     /translation="MYDNPSSNETVRCSFCGKTQEEVKKIVAGPGVYICNECIDLCKE
                     IIDEEFYEEAVREFTEVPKPLEILEVLNNYVIGQDRAKRSLAVAVYNHYKRVNQQAQE
                     NTDDVELQKSNICLIGPTGSGKTFLAQTLAKTLNVPFAIADATSLTEAGYVGEDVENI
                     LLKLLQSADYNVELAEKGIIYIDEIDKIARKSENVSITRDVSGEGVQQALLKILEGTV
                     ASVPPQGGRKHPHQEFIQIDTTNILFIVGGAFDGIETIVKNRMGEKTIGFGTQNQKLS
                     EDESVMQHIIPEDLLKFGLIPEFIGRLPVMAALEKLTTDDLVRILTEPKNALVKQYQK
                     LLSLDNTELEFEPEALRAIAKKAIERNTGARGLRSIIEEIMMDVMFDIPSNENIEKVI
                     ITKEAAELSGEPTVIYKDSEKKAG"
     gene            complement(7897..9186)
                     /locus_tag="LLC22_001866"
     CDS             complement(7897..9186)
                     /locus_tag="LLC22_001866"
                     /EC_number="5.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323981.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trigger factor"
                     /protein_id="HBK5435143.1"
                     /translation="MTATFEKKGTNDGVLKFTIAQDEIQKGLTTAFNKVKKSLNVPGF
                     RKGKVSRQVFNRMYGEEALYEDALNAVLPEAYEAAVKEAGIDPVSQPKIDVESMEKGQ
                     DWVITAEVTVKPEVKLGQYKDLVVEKQDREVTDADVDARIKREQEAQAELVIKEDAAA
                     ENGDTVVIDFEGFVDGEAFDGGKGENYSLELGSGSFIPGFEDQLVGHKSGESLDVNVT
                     FPEDYQAEDLAGKEAVFKVTIHEVKAKEVPELDDEFAKDVDDEVSTLDELKEKYRKEL
                     VETKEKAADDAKDEAAIRMAVENAEIVELPHVMVHDEVHRSMDEFLNNMQRQGISPEM
                     YYQLTGSTEEDLHKQFEGEAEMRTRTNLVIEAIAAAENLQATEEEINAEIQELSETYN
                     MPIEQIKRVLTEDMLEHDVTMKKAIELITGTATEAKE"
     gene            complement(9340..10272)
                     /locus_tag="LLC22_001867"
     CDS             complement(9340..10272)
                     /locus_tag="LLC22_001867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435144.1"
                     /translation="MKPIDFPEKYENLMRVAQQALANQQYQQAKELFQRAYELKESFE
                     ANSLLVFCLYELDEKKEALKQALLHEKQYLQNEEFAEFYFDLLISTQDFLYARKLIAS
                     TDFYEAFEQRVIEKIQFAEELSGQMERQKIKALHNKSEELPSLEPARQLASIDEIEQL
                     PYHEFIQTASKLIVSPEVHILARAKLLETLRQLNECHPVFYLTIEEKLVKVIPKDLPK
                     PQQQASYQQLCVFSDRYGNEDALLSSVLKEEFTLQSAIVYPVYDTYIEDPKRWFQLTV
                     EACTGKTMYEGTEDEKQDFLKKREKILQQMIFFH"
     gene            complement(10429..11088)
                     /locus_tag="LLC22_001868"
     CDS             complement(10429..11088)
                     /locus_tag="LLC22_001868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RDD family protein"
                     /protein_id="HBK5435145.1"
                     /translation="MSELSNENKEQEKDKQQQPAVGPDSNFSQKVLSSFEREPLTPEE
                     IKKKQRKWKKYTDTRNEPPKANDFPKYFYAGFFIRMFAFLVDLLCIGAITRLTLGIAK
                     NLGWLNFSDSYLSLYGFTALLIYLAYFILLTKFNHGQTIGKMIFGIRVISFDEEELSW
                     STVLVREGACRFILKFPLLMLGYLPAVFNQKKQHLGDFFTNTSVVTINLIKAFNQEVN
                     S"
     gene            complement(11091..12116)
                     /gene="sppA"
                     /locus_tag="LLC22_001869"
     CDS             complement(11091..12116)
                     /gene="sppA"
                     /locus_tag="LLC22_001869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337680.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptide peptidase SppA"
                     /protein_id="HBK5435146.1"
                     /translation="MNKRRWAAVLIAAGLFVVSLVSASLTKPQENDQIEGLNSWLYGD
                     EELAPNVLEEGDSTQKIVKLSVDGTIAAGGSSGLFASEGYNHKNFMEQLKAIEEDPTV
                     KGIFLEVNSPGGGVYESAEIAKKLDTIRKEHDIPMYVSMKNMAASGGYYISAQADKIF
                     ATEETVTGSIGVIMSGLNYSGLLEKLGVEDTTVKSGALKDMGSGTRPETKEEEAVLQA
                     YIDSAYSRFVAIVSEGRNKSEEEVKKIADGRIYDGVQAKEVGLVDELGFPEDALKAIR
                     KEQQLEDAELVEYSSTPSGFASTWLGSKLAEFQGLKPSETSQILSVLENLGTAESPKA
                     MYYYGGE"
     gene            complement(12129..12419)
                     /locus_tag="LLC22_001870"
     CDS             complement(12129..12419)
                     /locus_tag="LLC22_001870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435147.1"
                     /translation="MDSKIEIMTLGMLKKQLSKFEASAGVSDDTKIFLDTGWDSIQEI
                     APDALEVAQAREFTVEDELTKESFSGYAREEKAERFDTSEQSETVIVIKNLY"
     gene            12828..14633
                     /gene="glmS"
                     /locus_tag="LLC22_001871"
     CDS             12828..14633
                     /gene="glmS"
                     /locus_tag="LLC22_001871"
                     /EC_number="2.6.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamine--fructose-6-phosphate transaminase
                     (isomerizing)"
                     /protein_id="HBK5435148.1"
                     /translation="MCGIVGMIGLKNVTPGLIDGLEKLEYRGYDSAGIFVSDGTTDYL
                     VKAQGRIQNLKNKINIDTTGNIGIGHTRWATHGQPSEENAHPHTSQSGRFVLVHNGVI
                     ENFEELKIAYLANDHFIGETDTEIIAHLIETFAKDTTTQEAFLKALRVIKGSYAFALI
                     DRTAPDVIYVAKNKSPLLIGLGDGFNVIASDAMAMLAHTKEFVEIEDEEMVTVTSEKV
                     IIQNFAGDIVERSSFEAQVDASDIEKGTYPFYMLKEIDEQPIIMRRIAQKYVTEDNRV
                     SLDQKLVDTLSDSDRIYIVACGTSYHAGLAGKQTLEKLTQIPVEVHLASEFGYNTPLL
                     SKKPFFIFLSQSGETADSRQVLVKINRLGYPSLTITNVAGSTLSREASFTLLLHAGPE
                     IAVASTKAYTAQIAVLTLLAKAIGDKKEFETSLVFDITHELSLVANAMESVIAQKDYL
                     EELAEVYLSDTRNAFYIGRGADYNVSLEAALKLKEISYIQAEGFAAGELKHGTIALIE
                     EGTPVIGIISEEVTGAHTRGNLKEVESRGAKTLVIVSEGLEKESDQLVLPTVHPYLTT
                     LTTVVPTQLLAYYATLLRGFDVDKPRNLAKSVTVE"
     gene            complement(14705..16060)
                     /locus_tag="LLC22_001872"
     CDS             complement(14705..16060)
                     /locus_tag="LLC22_001872"
                     /EC_number="5.4.2.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010739004.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglucosamine mutase"
                     /protein_id="HBK5435149.1"
                     /translation="MGKYFGTDGVRGEANKELTPELAFKLGRCGGYVLSQHEEEGKRP
                     RVLVGRDTRISGQMLEEALISGLLSVGIEVFQLGVISTPGVAYLTRLQKASAGVMISA
                     SHNPAQDNGIKFFGADGFKLVDDQELEIEALLDAEVDELPRPSAEGLGTVEEFPEGLL
                     KYSQFLVQTINGDLSGLTICVDAANGATSTSVNRLFADLETDFYTMGTNPDGLNINDG
                     VGSTHPERLAEMVVEKGADAGLAFDGDGDRIIAVDELGNIVDGDKIMFICAKYLAEKN
                     RLKKDTIVTTVMSNLGFHKAVEGIGLKDVVTQVGDRYVVEEMRKNDYNFGGEQSGHMI
                     FLDFNTTGDGMLSGIQLLNIMKQTGKKLSELAAEVTIYPQKLVNIRVSDKNGAMDVPA
                     IKKVIEEAEAEMGSEGRILVRPSGTEPLLRVMAEAPTDEKVNYYVDKIAAVVKEEIGL
                     D"
     gene            complement(16084..17253)
                     /locus_tag="LLC22_001873"
     CDS             complement(16084..17253)
                     /locus_tag="LLC22_001873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435150.1"
                     /translation="MISKEKRTSILYSFIALLFSIALYFNANGQSVPNTLSGNEAYNQ
                     TVTGVPIKISYDSKRYYIHGYENAVTVKLSSANRVQLNAEANEDTRMFRVTADITKLG
                     EGTHEVPLKIQNLSSAVTAKIEPSTITVTVEKKVIKDFDVETLIPSTFTPSGYELDDT
                     SVSPKKVSITTGDKTLAEIKRVVADVDASMVTDDGINSEVPIQALNAAGEVLSIVSDP
                     VQVTVRADSIKPSKSVRLYGIQQGTPAAGVESYDFSFSKLEAEVSGSSDLLASIGDSI
                     AVPINVSGINHRTTRKIEIPVEEGLSIKPESVSVEITPVLQTSSSSSASTSSRTQENT
                     STSRSISSADSGTEPSTTTISSSSESGTSSSTTSTEETSETSESTQMSRTNSSEN"
     gene            complement(17250..18137)
                     /locus_tag="LLC22_001874"
     CDS             complement(17250..18137)
                     /locus_tag="LLC22_001874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00159 family protein"
                     /protein_id="HBK5435151.1"
                     /translation="MSFQIGELFNLDYWQQMFSGDLFSLNFLVNILDILVVWYLVYKL
                     IQLLRGTKAIQLLKGVAIFIVIRIVAEIIGLHTLSWLMNQVITYGVIAAIVIFQPEIR
                     RGLEHLGRSSLFKQSKSEQQEDEKMILSFDKAIQYMSKRKIGALITIERHTGLDEYIE
                     TGIALDADITGELLINIFIPNTPLHDGAVIVKEGKIAVASAYLPLSESMLIPKEFGTR
                     HRAAVGISEVSDAITIVVSEETGDVSITLDNELMAGLSQQEYLAILRRELIAEEKTKN
                     KKNVIQSFLDGMTKGGDRK"
     gene            complement(18326..22018)
                     /gene="nifJ"
                     /locus_tag="LLC22_001875"
     CDS             complement(18326..22018)
                     /gene="nifJ"
                     /locus_tag="LLC22_001875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate:ferredoxin (flavodoxin) oxidoreductase"
                     /protein_id="HBK5435152.1"
                     /translation="MRKMKTMDGNTAAAYISYAFTEIAAIYPITPSSTMAELVDQWSA
                     AGKENVFGQPVKVVEMQSEAGAAGVVHGSLKTGALTTTYTASQGLLLMIPNMYKIAGE
                     LLPSVFHVASRAVTTNALNIFGDHGDVMAARQTGFAMLAESSVQEVMDLAPVAHLASI
                     EGEVPFLNFFDGFRTSHEIQKIEVLEYEELAPLINQEKLASFRKRGMNPNHPTVSGTN
                     QNPDIHFQQRETINPYYDKLPEIVQKYMKEINRLRGTSYDLVTYYGADDAEEVIVSMG
                     SVAQTIEQTIDYLNANGRKTGFLNIHLYRPFPVETFVQKLPHTVKTIAVLDRSKEPGA
                     GGEPLLLDVQSALYDSELRPAVIGGRYGLGSKDVTPDQISAVFDELKKDPSIRKKRFT
                     IGIVDDVTYQSLEPKESLDLTEPQTFQAKFWGFGSDGTVGANKSAIKIIGDHTDKYAQ
                     GYFYYDSKKSGGLTVSHLRFGDTPIRSAYLVEHADLVACHTPAYLHSYDLVKGLKPGG
                     IFLLNTLWSDEQLETHLPLKLKRYLAENNIRFYTINAMRLAQEVGLGRRINTAMETAF
                     FKLADIIPFDEVLPLLKEEALKSYGHKSMAIVEKNIQAIDRTTELLHQVAIPDHWRTL
                     EMPEKINKRNTGYIQEILEPVNAQEGNQLSVGTLVANGMTTGEMPLGTASMEKRGVAL
                     EVPEWISDRCTMCNECAFVCPHAAIRPFLADEEEMEEAPEGFIVREMRGADGVKYRIQ
                     VSVEDCTGCGLCVEACPAKEKALVMKPYEEQKEQAVNWAFAMTLRQKANPVKGKNTVL
                     STQFNQPLLEFSGACSGCGETPYVKLLTQMFGDRMMIANATGCSSIWGGASPASPYTT
                     NECGQGPAWSNSLLEDNAEFGYGMLLAAQTRREALASSIKEVLPKVSEELRELMEDWL
                     VHMFESEGTQQRAAKLQAAIESERSIFPELEDIYKRKDLFVKNSQWMIGGDGWAYDIG
                     FGGIDHVLASGADVNILVLDNEVYSNTGGQTSKATPASAIAKFSASGKYASKKDLGMM
                     AMTYGNVYVAQIASGANQMQTIKAFEEAEKYPGPSLIIAYTPCITHGLLGGMKESLKE
                     AKEAVSSGYWSLYRYNPTMVEKNKNPMTLDYKKPDFSAMPDFMRKQVRFSSLDNANPN
                     LAKALFEKTVHDAKTRFYNYAALTGELEKIKKRLEPEESIDVPVKTRKEKTTDLEAEE
                     RRAARRAARAERRKKMEQATKEKKEK"
     gene            22217..22738
                     /locus_tag="LLC22_001876"
     CDS             22217..22738
                     /locus_tag="LLC22_001876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DsbA family protein"
                     /protein_id="HBK5435153.1"
                     /translation="MDISVIDATKTNTQKGILYGSSNAPKKMVEFINLACPYCRQWFE
                     ESYELLEEAVQSGQLQRVIKLFDKEKESLQRGNVMHRYLTISDGQKAIKEIKQIFDTQ
                     DEWKHLSLQEVADFAVDKLKLTEQKDEQLSQAVINEAEQAHIRFVPTVILGKEIFDES
                     ISIEELKELIQTK"
BASE COUNT         6491 a         5044 c         4121 g         7600 t
ORIGIN      
        1 aaaaaaagaa gaggctggga aaacccagcc tcttcttttt tatttctatg cttctgctac
       61 tgcaggagct tttctcaata aaccataaat cacaccagat acgactgctc cgatagcaat
      121 aaacaccaaa tacatgaccg ggtgactcag taagaataca acgaaaatcc cgccgtgagg
      181 agccagtaat ttgattccga aagctccgac taatccgcca gttaaagcag aaccaataat
      241 aaaacttgga atggcacgaa tcgggtcagc tgctgcaaat ggaatcgatc cttccgtgac
      301 aaacgatagt cccatcacga tgttcgtcaa accagcatct tgatctgttt tgctgaattt
      361 attcttaaac aaacgtgtag caacgaaaat tgccaatgga ggtaccattc ctccagccat
      421 aacagaagcc atcacgacac ttccgccagt tgcaacagtc gtagctaaag ttgctgtacc
      481 aaacacataa gcggctttgt tgattggacc gcctaaatct gccgccatca ttccagctaa
      541 taatgcacca agtaaagcag cattcgaacc actcatactt gtcaagaaac cgttcaatgc
      601 atcattgatt gctttcatag ggacattgac cagcaacatc aagaaaccag taatcagtaa
      661 gccaaacact ggataaaaga ggatcgtttt aattccatcc aatgattttg gtaagttctt
      721 gaataattta cgtaaaaata cgatgacata accagctaag aatccaccaa tcagtgcacc
      781 taagaatcct gcaccgcctg tattagctaa tgcaccagca gcaaatccaa cgatcaaacc
      841 agggcggtca ccgatacttg aagcaataaa tcctgctaat accggcagca tgaaaccaaa
      901 tgcagcttgt ccgatttggt tgaaccagct agcagcttga ttgtaattcc ctagatttga
      961 taattgatca tgtggcacgc caataaattg gtcgatcatg aaagaaagcg caatagcgat
     1021 tcctccacca ataacgaaag gtaacatgtg tgatacgccg ttcatcaaat ctttgtaaat
     1081 tctttgtccg atagtaccat ccgcatttcc ttcttctgaa ctgctttctt ttccatcacc
     1141 atggaatact ggtgcagtac cactaagggc tagattgatc aactcttctg gtttacggat
     1201 accatcactg acaggacgat tgatcagttc ttttccgtca aagcgattca tctctacttt
     1261 tttgtctgct gcaacgatta caccttctgc acgggcgatg tcttcagcag tcaatcggtt
     1321 tttgattcct tctgaaccgt tcgtttcgac tttgatctcc acacccattt ctttcgcttt
     1381 tttcttcaaa gcatcttctg ccatgtaagt gtgagcgatc cctgttggac aagctgtaac
     1441 ggcaacaacg aattttcttt ctggatgagc agaagcttct gcagcttgtg tttcttgttc
     1501 tgctttttct tctgcttctt tttgctcttc agctgtttgg aacaagtctt ggacttcttc
     1561 tggtgtattt gcttctttta attttcctac gaaatctgca tcaatcagca atcgagatag
     1621 tgctgctaat gcttgcaaat gtgtgtcgtt tgcgccttct ggagctgcga tcatgaaaaa
     1681 cagataagtt ggctgtccgt ctaaggcttc ataatctact cctttttggc tttttgcgaa
     1741 taaaactgtt gcttctttaa ctgcactgtt tttcgcgtga ggcatggcga ttccatcacc
     1801 aagacctgta gaagtttgtg cttcgcgggc tagaattcct tctttatatg tttcgatatc
     1861 ggaaatccgg ccggcatcaa acattttttg gaccatttca tcgattgcgc cttttttatc
     1921 agtcgcttgc aaatccatga tcatcgcttc tttgaccatt aaatccttga tattcatgat
     1981 tatcctcctt gaaactaatc aatttttgtg atttcaactt ctggcagcaa ctcatcaatc
     2041 aattcgcgag ctgccaagtc atcagaaaaa gctgttgcgc ttccgcaagc aactccccat
     2101 ttaaaggctt cgattggatc tttcgtacgg ctgtaagccc caataaagcc agcaatcatt
     2161 gaatcccctg cacctactga atttttcaat gggcgaacta atacattcgt tttataagtt
     2221 ccttgttccg tgaagagcaa agcaccgtct ccagccattg agatcagcac attctgtgcc
     2281 ccttcagcta gtaatttttt cccatacgga atgatttctt ctacagattg gaaggttgtg
     2341 ttgtaaagct cagctaattc gtgattgttt ggtttgatca acaacggttt cttaacaagt
     2401 gcatttttta ggtcatcacc tgttgtatca atcacgaaat ctgcaccttt ttctcgaatg
     2461 atatcaatca gttcttgata aaatcctttt cgcaggctag ctggcgcgct tcctgacaat
     2521 acgacgatat ctccttgtcc tactgttcct aatgcttgct tcaactcatc gatttcttca
     2581 tctgaaatag atgggcctaa gccattgatc tcagtttcag tgtctgattt tagtttgata
     2641 ttgattcttg tatcttcttt tacggttgtg aacaaagact ggatttgttc tttttcaagc
     2701 cacttcgaaa taaattcgcc agtgaaccct cctaaaaacc ctagtgctgt agattgagaa
     2761 tcgatccgtt tcaaaatacg ggaaacattg atcccttttc ctccaggtaa cttgaagtct
     2821 tccttcattc ggttcaaatc gcctagtttt aacccatcta cgcgtacgat ataatcaatt
     2881 gatggattaa gtgttactgt gtaaatcatt gtattgcctc cttaattgtt gtcttttcac
     2941 ggaattcatt aacgaattct aatggacaac gctcggttat gatcgtggct gcttccaaag
     3001 gtgcaacaga ggtgaaggac aactggttga atttggtatg atcaatcaat acaaatgtct
     3061 cttcggaatt tttcatggct aaacgtttaa cagctgcctc ttctggatcc ggagtcgtga
     3121 atccttgttc aagatgggca ccgttcattc ccataaatgc tttattaaaa tgaaaatttt
     3181 ttagttgttc tatcgcatta gatcctaaaa cagcattagt tgccagcttt atcgttccac
     3241 ctaaaataat ggtagcaagc tccaaatcaa ctaaatttgc cgcatgttga acggaatttg
     3301 tcactactgt gatctgtttt ccttgcagaa aaggaatcat ttctaacgta gtagagccag
     3361 cgtctaaata aatgacatct tcgtcattaa tggtttcagc tgccgatttg gcgatttgct
     3421 gtttttcgtg aacgtttttg agtgattttt cactcatatt ctgctcaaaa ttcaataatt
     3481 gctctttctt agctccgcca tgaactcttt ctagaaaccc actattctcc agctcttgta
     3541 aatcacgtct tatcgttgat tcagaagcat tcaaaaggtt tacaagatct tgtgatttca
     3601 cgattttctg ctgttcaagc aagtctagga ttttttgtct gcgttcctct gtaagcattt
     3661 tcacgatcac ctcaatacaa ataatagcat attttttttc tactagcaat ataaatcagt
     3721 caaaaacgtt cataaaaatt ataaatcagt caaaaaaaaa taaaaaacca gtcagaaaga
     3781 ctggtttttt atttttttgt ctatcatcaa gccgttttat cgttttttat tttcgcttct
     3841 tgtttttttc atataaacag aagcaggttt tctttcctta tgaagaagat aataataaag
     3901 tcccatcccg ccaaacatga ccaaaaaacc gatgactgat cgaataggaa aattaggaac
     3961 aaaaaagaga cagacggata ataatgatgc cggaaccatt attcgataat agagttgttt
     4021 atccattttc ttcacctcat attttttgta aagtaatcaa ttgttctaat tctcggtaat
     4081 ctaaaaattg cacacgcaga tgctgctcac ctttcttgac atcgaattgg atacttcgcc
     4141 gctttttctt tattcgtttg aaggtaacat cagagagtct atgtttgatt tcctttaacg
     4201 gtaattctga cagggattct gaaggaacat agattcttaa ggataaaaga tactcttgat
     4261 atttttcatc tgttacctct acttctagat attccctaat ataataacaa taagcttcga
     4321 ttccattatc caaagcaaca gtcggatcga taactttata gcacatcatg cgtgatcgat
     4381 tctcgtcaac ccaaggaaaa tacgcctgag catttagtgt tccgcgaaca cgcctttctt
     4441 tataatctcc ttgttggata tcataacttt ttgttacaaa aaatgaagca ttctttttag
     4501 gaacaggttg catttgtgca ttctgatact ggacagattg gatcgtatgg tcagtgtaaa
     4561 tgtattcaac gaatggcggt ttcaataaac cgacaccatt gtcccaagca agatgatcaa
     4621 acccaagctg gtccctaaaa taggattgaa acatttgatt gtttggcttt tgccagttaa
     4681 aggggtctcg ataaagctgg atacatatga cttcgttttc taattccttc actttttcta
     4741 cttgttggat gtcgagaaaa atcggtttag ggatgatttg atgataatag cgactataat
     4801 acatttccca acacgaagtg aaacataaac cttggtaaaa aagatcgtat cctggaaatt
     4861 ggttgcaatc gactactact tccccgtttt gttgtttcat tttaggtaaa tgttcgattt
     4921 catccttttt ctcaaacaat agccgttgag agatctgttt tgtattgtga tagataaact
     4981 cgctataagc tcgcatatag gcgaacaccc catgagcaat catttttttc tgaatgaagt
     5041 ctcgaatcaa aaattgcttt tctttgaaaa cagagataga caatacattt tttatcaata
     5101 attgattatc ttccaagcga aaactacatt cgttctcgtc atttcctaca actaaccaac
     5161 tttcgtctct taccgatgct agcattattt tttcttgaag ctttcgaaga tcatacggat
     5221 ccgcttgttg tgtgaaagag cggataaatg ttggctggat caacagacgt gtcaaaatag
     5281 cccaatcgct tatttcctgt tttttttctt cttcatttaa gtctgtgagc tggatagtca
     5341 tcaataattt atcttcgcca atcattttct cacctctttc aaatcttttt ataatttaat
     5401 tataaccaat gataaagaaa aactaaaact ttatgtctta gaaaccaatt tggacgatta
     5461 catgatagac taagtaaaaa gaaacaaaga ggtgtttaca atggggttga aatttgaacg
     5521 tacagataat ttagataaac ttttcgaatc atttgctgtc gatccggaaa aaacagttgc
     5581 accaaaagaa gagatcgatc gatttctaaa accacagcca caaaatgaaa agaaaaaaga
     5641 caagaaacaa aagtaagtta agctcaaaaa aagacttacc agccaaactt ttatgaaaga
     5701 gtttgactgg taagtctttt ttattctttt tatgattcaa ttgcttgttc gattgctgcc
     5761 cacgcttctt cttttccctg ttttgtaacg gaagaaaaga gaataaacgt gtcattgcga
     5821 tcaaaatcca acgctttttt gatttcgctc tcatgcttgt tccatttacc acgagggatc
     5881 ttatctgcct tagtggcaac aacaattaca gggatatcat aatacttcaa aaattgatac
     5941 atctggatat cttcttgaga aggcttatga cgcaaatcta ctaaagaaac gaccgcacgt
     6001 agctggtctc tagtcgttaa atatgtctcg atcatctttc cccattttgc tcgctcagtt
     6061 ttggatactt ttgcataccc atatcccgga acatcgacaa aatgtaatgc gttctcgatc
     6121 aaataaaaat tcaatgtctg ggtctttcct ggcttaccgg aagtacgggc taaattcttt
     6181 cgatcaatca atgtgttgat aaaagaagat ttccctacat ttgatcgtcc tgccagagct
     6241 atttctggca attgtgtatc tggatattgt tttggtgcca ctgcacttat gataatttca
     6301 gcttgatgga ctttcatggt ctctctcctt aacaaggtga tgaataaagc aagcggctgt
     6361 cgcaaaagcc aaaatgactt ttacggcagc ctcttttcat caacccgctt ttttctctga
     6421 atctttatag attactgttg gctcaccaga caattcagct gcttcttttg tgataatcac
     6481 tttttcgatg ttttcatttg aagggatatc aaacatcaca tccatcatga tttcttcaat
     6541 gatggaacga agtcctcgag caccggtatt gcgttcgatt gcttttttcg caatggctct
     6601 caacgcttca ggttcgaatt caagttcggt attatctaga gaaagaagtt tttgatattg
     6661 tttgactagc gcatttttcg gctcagtcaa gatccgtacc agatcatctg ttgtcaattt
     6721 ctctaaagct gccataacag gtaatcgtcc gataaactca gggatcaatc cgaattttag
     6781 taaatcttca ggaatgatat gctgcatgac actttcgtct tcagaaagtt tttggttttg
     6841 tgtaccaaat ccaatcgtct tttcgcccat acgattcttc acaatcgttt cgatgccatc
     6901 aaatgcacca cctacgatga acaatatgtt cgtcgtatca atctgaataa attcttgatg
     6961 tggatgttta cgtccgccct gaggtggcac acttgcaaca gttccttcta gaattttcag
     7021 caaggcttgt tggacacctt cgccggaaac gtcacgagta atagatacat tttcgctttt
     7081 acgcgcaatt ttatcgatct catcaatata gatgatccct ttttctgcaa gttccacatt
     7141 gtaatcagca gattgaagca atttaagcaa aatgttttct acatcttccc ccacataacc
     7201 agcttctgtc aaacttgtcg catctgcgat tgcaaaaggt acattcaatg tttttgctaa
     7261 tgtttgtgct aaaaatgttt taccagaccc tgtaggtccg atcaagcaga tattgctttt
     7321 ttgcagttca acatcatctg tgttttcttg tgcttgctga ttgacacgtt tatagtgatt
     7381 gtatacggca acagctaacg agcgttttgc gcgatcttgt ccaatcacgt agttattcaa
     7441 tacttcaaga atttctagtg gtttagggac ttcagtgaat tcgcgtacag cttcttcata
     7501 aaattcttca tcaatgattt ctttacatag gtcgatacat tcattacaga tgtagacccc
     7561 tggaccagct acgatctttt tcacttcttc ttgggttttc ccgcaaaaag aacagcgtac
     7621 ggtctcattg ctacttggat tgtcatacat ggtcttcacc ccttaacttg caaaaagtat
     7681 gcaagaaact atcaaagact ttacagtctt ttactatcat aacatagttt agtaaaaaga
     7741 aaaagtgttt aacaaaggat caactgacct atacctttgc attttttact cttaacaaaa
     7801 aataaggaac tgtgacaaaa tcgtgtcaca gtcccttatt tcgaataaac aattttctag
     7861 aagtagcttc ttcagaaatg atttattact tgatttctat tctttcgctt ctgtcgctgt
     7921 acctgtgatc aattcgattg cttttttcat tgtcacatca tgttccagca tatcttctgt
     7981 caacacgcgt ttgatttgtt cgattggcat gttgtatgtt tctgataatt cttggatttc
     8041 tgcattgatt tcttcttctg ttgcttgaag attttcagca gctgcaattg cttcgatcac
     8101 aagatttgtt cttgtgcgca tttctgcttc accttcgaat tgtttatgca agtcttcttc
     8161 tgtagaacca gttaattgat agtacatttc aggagagata ccttgacgtt gcatgttgtt
     8221 caagaattcg tccattgaac gatgtacttc atcatgaacc atcacgtgtg gcaattcaac
     8281 gatttctgcg ttttcaacag ccatacggat cgctgcttca tcttttgcat cgtccgctgc
     8341 tttttctttt gtttctacta attctttgcg atatttttct ttcaattcgt ctaatgttga
     8401 tacttcgtca tcaacatctt ttgcgaattc gtcatctaat tcaggcactt cttttgcttt
     8461 tacttcatgg attgtcactt tgaagactgc ttcttttcca gcaagatctt ctgcttgata
     8521 atcttctggg aaagttacat ttacatctag actttcacct gatttatgac caactaattg
     8581 atcttcaaaa cctggaatga atgagcctga acctaattca agtgagtaat tttcgccttt
     8641 tccgccatca aacgcttcgc catctacaaa gccttcgaag tcgattacta ctgtatcgcc
     8701 attttcagct gcagcatctt ctttgataac taattcagct tgtgcttctt gttcacgttt
     8761 gatacgtgca tccacgtcag catctgttac ttcacggtct tgtttttcaa caactagatc
     8821 tttatattgt cctaatttta cttctggttt cactgttact tcagcagtga ttacccagtc
     8881 ttgacctttt tccatgcttt caacatcgat ttttggttga gaaacaggat cgatgccagc
     8941 ttctttgaca gcagcttcat aagcttctgg taatacagca ttcaatgcat cttcatataa
     9001 agcttcttca ccgtacatac ggttgaatac ttgacgagaa actttccctt tacggaatcc
     9061 aggtacgttc aagctttttt tcactttatt aaacgcagtt gttaatcctt tttggatttc
     9121 gtcttgcgca atcgtaaatt ttaaaacacc atcattcgtg cctttttttt caaatgttgc
     9181 agtcatttaa ttccctccga gtttagaaat tcattttata catcaaaaac gtttcatgca
     9241 tacctttaaa tagtacacta accctttcaa attgtaaaca tattgaatgg atagaatcct
     9301 tgtttttcat aacattttta tctttttcac tgataaaatc taatggaaga agatcatttg
     9361 ctgcaaaatt ttttctcttt tttttaaaaa atcttgtttt tcatcttctg taccttcata
     9421 catcgttttt cctgtacacg cctctacagt cagttgaaac cagcgcttcg ggtcttcgat
     9481 gtatgtatca tagacaggat aaacaattgc agattgcaac gtgaattctt cttttaacac
     9541 ggaactaagc agcgcatctt cattcccgta acgatctgaa aatacacata attgctggta
     9601 acttgcctgc tgctgcggct ttggcagatc ttttggtatg actttgacta acttttcttc
     9661 aatcgtcaaa tagaaaacag gatggcattc gttcaattgc ctaagtgtct ccagtaattt
     9721 tgcccttgct aaaatatgga cctctggcga tacaataagt ttactcgctg tttggataaa
     9781 ctcatgataa ggaagctgtt cgatctcatc aatagacgca agctgacgtg caggttccaa
     9841 cgaaggaagt tcctccgatt tattgtggag tgccttgatc ttctgcctct ccatttgtcc
     9901 ggataattct tctgcaaatt ggattttttc aatgacccgc tgctcgaaag cttcataaaa
     9961 atctgtactt gctatcaatt ttctagcata taaaaaatct tgtgtactga ttaacaagtc
    10021 aaaataaaat tcagcaaact cctcattttg aagatactgt ttttcatgca agagtgcttg
    10081 cttcaatgct tcttttttct cgtccaactc gtaaagacaa aaaacaagca ggctattagc
    10141 ctcaaagctt tctttcaact cgtaagctcg ttgaaataat tcttttgcct gctgatattg
    10201 ctggtttgct agtgcttgtt gtgccactcg cattaaattc tcatattttt ctggaaaatc
    10261 aatcggcttc acgcagtgtc ctcctcttgc tcatattcag ctcatgttca atagtagcaa
    10321 aacaaaaaaa gcatgacaat taaaaataac tgaagcaccc tctaaaagct agattttaga
    10381 tctgactttt agaaggtgct ttcaactgtt actgcttttt attgctcatc agctgttgac
    10441 ttcctggttg aacgctttga tcagattgat cgtaacaaca cttgtattag tgaaaaaatc
    10501 gcccagatgt tgctttttct gattaaagac tgctggaaga taccctaaca tcagcaaagg
    10561 aaattttaga atgaaccggc aagcaccttc tctaactaaa acggttgacc agctaagttc
    10621 ttcttcatca aagctgatga ctcgaatacc aaagatcatt ttcccaatcg tttggccatg
    10681 attgaatttc gtcaataaaa taaaatacgc tagataaata agtaaggctg tgaatccgta
    10741 gagactcaga taagaatctg aaaaattaag ccaacctaga tttttggcaa taccaagtgt
    10801 taaacgcgta atagctccga tacacaaaag atcgaccaag aaggcaaaca ttcggataaa
    10861 aaaacctgca tagaaatact taggaaaatc atttgctttt ggcggttcat ttcttgtgtc
    10921 cgtatacttt ttccatttac gttgtttctt tttgatttct tcgggcgtca aaggctctct
    10981 ttcaaaagag ctcagtacct tttgggaaaa gttggagtca ggtcctacag caggctgctg
    11041 ttgcttatct ttttcttgtt ccttattttc atttgaaagc tctgacatgc ttactcacct
    11101 ccgtaataat acattgcttt tggtgattcc gctgtcccta gattctcaag aacggataag
    11161 atctgactag tctcagaagg cttcaatccc tggaattctg ctagtttact tcctaaccat
    11221 gtactagcaa acccagatgg cgtggaagaa tattctacta gttccgcatc ttcaagctgt
    11281 tgttcctttc gtatagcttt taaagcatct tcaggaaatc ccaattcatc gactaaacct
    11341 acttcttttg cttggacacc atcataaatc cttccatcag caattttttt gacttcttct
    11401 tcagatttat tccgtccctc gctgacgatt gctacaaaac gactatatgc gctgtcgata
    11461 tatgcttgaa gcaccgcttc ttcttctttt gtctctggtc gcgttcctga acccatatct
    11521 ttcaacgctc cgcttttaac tgttgtatct tccacaccca gtttttctag aagtcctgaa
    11581 taattcaatc ctgacatgat cacaccaatt gagccggtca ctgtttcttc tgttgcaaag
    11641 attttatctg cttgagcaga aatatagtag ccaccgctag ctgccatgtt tttcatgctg
    11701 acatacattg ggatatcatg ttctttacga atcgtatcca atttcttagc gatttccgca
    11761 ctttcgtaga caccgccacc aggagaattt acttctaaaa agataccttt gactgttgga
    11821 tcttcttcaa tcgccttcag ttgttccata aaatttttat gattgtaacc ttcagaagca
    11881 aataaacctg aagaccctcc cgcagcaatc gttccatcta ctgataattt tacgattttt
    11941 tgcgtactgt ctccctcttc caacacattt ggagctagtt cttcatcccc atataaccaa
    12001 ctgttcaatc cctcaatttg atcgttttcc tgaggcttag tcaaactagc tgaaactaac
    12061 gaaaccacaa ataatcctgc agcaatcaga actgctgccc aacgtctttt attcattctt
    12121 tctcctttct aatacaagtt ttttatgacg atcacagttt ctgactgctc agaagtgtcg
    12181 aaccgctctg ctttttcttc ccgcgcatac ccggaaaacg actcttttgt taattcatct
    12241 tctaccgtaa actcacgagc ttgagcaact tccaaggcat caggtgcgat ttcttggatg
    12301 ctatcccagc cagtatctaa aaatattttc gtatcatctg atacaccagc tgatgcttcg
    12361 aatttggaca attgtttttt taacattccc agtgtcatga tctcaatttt tgaatccatt
    12421 tttactcctc ctctatccga ttactttcta ttgtaccgaa ctcctgaaaa agatgataga
    12481 taaaaaccca ttattttttg acataaaaag gacatttgac aaagaatttg atatatacca
    12541 atttattttt tattcttttt ttgttgacaa gaacattcgc aaaaggttat gattttaaat
    12601 gtttccagat aaaaaacaaa aaggaggata gttatacctt ttaggatagc gccaggtctg
    12661 tgtaaacaga tgacgaggag agggtttatc gaaagattcg gcggatggcc ctagggactg
    12721 cactctacag aaaatccaca aaaaatgtct gcaaagataa aacaaaagga ttttcctgca
    12781 gctggaagca ttcatacgaa ttcattatag aaagtaggat gttttttatg tgcggaattg
    12841 ttggaatgat tggattaaaa aatgtaacac caggattgat tgacggtcta gaaaaattag
    12901 aataccgtgg ttatgattca gctggtatct ttgtctcaga tggcacaact gattatctgg
    12961 tcaaagcaca aggcagaatt caaaatttga aaaacaaaat aaatattgat actacaggaa
    13021 atataggtat tggtcataca cgatgggcaa ctcacgggca accttctgaa gaaaacgccc
    13081 atccacatac ttcccaaagt ggacgcttcg tgctcgttca caacggcgta atcgaaaact
    13141 ttgaagaact taaaattgct tatttagcaa atgaccactt tattggtgag accgatactg
    13201 agattatcgc tcatctaatt gaaactttcg cgaaggatac tacaacgcaa gaggcgtttt
    13261 taaaagcttt gcgggtcatc aaaggttctt acgctttcgc tttgattgat cggacagcac
    13321 ctgatgttat ttacgtcgct aaaaataaaa gtccactatt aatcggactc ggcgatggat
    13381 tcaatgtgat tgccagcgat gcaatggcta tgcttgctca tacgaaggaa ttcgttgaga
    13441 ttgaagatga agagatggtt accgtcacat cagaaaaagt tattattcaa aattttgcag
    13501 gtgacatcgt agaacgttct tcattcgaag cacaagtaga tgcttcagat atcgagaaag
    13561 gtacctatcc tttttatatg ctgaaagaaa tcgacgaaca gcctattatc atgcgtcgta
    13621 tcgctcaaaa atacgtaaca gaagacaatc gtgtctctct tgatcaaaag ctggtcgata
    13681 cattgtctga tagcgatcga atctatatcg ttgcttgcgg aactagttac catgcggggt
    13741 tagcaggtaa acagactttg gaaaaattga cacagattcc tgttgaggtt catttagcca
    13801 gtgaatttgg ctataacaca cctcttcttt caaaaaaacc attctttatt ttcttgagtc
    13861 aaagtggcga aacagcagac agccgccaag tgctggtaaa aatcaaccgt ctcggctacc
    13921 cttcacttac gattacaaat gttgctggtt ctactctttc gcgggaagca tcctttacac
    13981 tgctattgca tgctggaccc gaaatcgcag tagcatcaac gaaagcttat actgcacaaa
    14041 tagctgtact aactttatta gccaaagcta tcggtgataa aaaagaattt gaaacttctc
    14101 ttgtattcga tatcactcat gaattgagtt tagttgctaa tgcgatggaa tcggtcatcg
    14161 cccaaaaaga ttatttagaa gagttggcag aagtatatct cagcgataca agaaatgcct
    14221 tttacattgg acgtggtgct gactacaacg tttctcttga agctgctttg aaattgaaag
    14281 aaatcagtta tatccaggca gaaggttttg ccgctggcga attgaaacat ggaacgattg
    14341 ctttgatcga agaaggaaca ccagtgatcg gaatcatcag tgaagaagtg actggtgcgc
    14401 atactcgagg aaacctgaaa gaagtcgaaa gccgtggcgc taaaacacta gttattgtct
    14461 cagagggatt agaaaaggaa agtgaccagc tggtgctacc aactgtccac ccttatctaa
    14521 ctactctaac cacagtcgta ccgactcaat tacttgcata ttacgcaacg ctattacggg
    14581 gattcgacgt tgacaaacca cgtaatttag cgaaatcagt gacagtagaa taataaaaga
    14641 acaaggacca gtgtcagaca tctgacactg gtccttgttc ttttattttt tatgaaaata
    14701 tctcttaatc cagtccgatt tcttctttga ctactgccgc gattttatcg acatagtaat
    14761 taactttctc atcagtaggc gcttctgcca tcactcgaag taatggttct gtaccggaag
    14821 gacgaactag gattcttcct tctgatccca tttcagcttc tgcctcttca atcacttttt
    14881 tgattgccgg aacatccatc gcaccgtttt tatcacttac gcggatattc actaattttt
    14941 gcggatagat tgttacctct gctgcaagct ctgataattt cttacctgtc tgtttcatga
    15001 tattcagtaa ctgaattcct gaaagcatcc catctccagt tgtgttaaaa tctaagaaaa
    15061 tcatgtgccc agactgctcg ccgccaaagt tataatcgtt tttgcgcatt tcttctacaa
    15121 cgtaacgatc accaacttgt gtaacgacat ctttcaaacc gattccttcc accgctttgt
    15181 ggaatcctaa gttactcatg acagtcgtaa cgatcgtatc ttttttcaat cgattttttt
    15241 ctgccaagta tttagcacag ataaacatga ttttatcacc gtcgacaatg tttccaagtt
    15301 catccaccgc aataatacga tcgccatcgc catcgaaagc tagtccagca tctgctcctt
    15361 tttcaacgac catctcagct aaacgttctg gatgggtaga gcctacgccg tcattgatat
    15421 ttaacccgtc tggatttgtg cccattgtat aaaaatctgt ttcaagatcg gcaaacaaac
    15481 gattaacact tgttgaagtt gctccgtttg ctgcatcgac acaaatggtc aaaccggaaa
    15541 ggtcaccgtt gatcgtttgt acaaggaatt gagaatattt caataagcct tctggaaatt
    15601 cttctacagt tcccaatcct tcagctgatg gacgaggcaa ttcatccact tcagcatcta
    15661 ataatgcttc aatttctagc tcttggtcat ctactagttt aaaaccatct gcaccgaaaa
    15721 atttgattcc attatcttgt gctggattat gagaagcaga aatcatgacc cctgcgcttg
    15781 ctttttgcaa acgtgtcaga taagcaacac ctggtgtaga gatcacacct agctggaaca
    15841 cttcgatacc caccgataaa agtcctgaaa tcagcgcttc ttctaacatt tgacctgaga
    15901 ttcttgtatc ccgccctact aacacgcgtg ggcgttttcc ttcttcttca tgctggctta
    15961 ggacataacc tccgcaccgt cccagcttaa atgcaagttc tggcgtaagt tccttgttgg
    16021 cttcaccgcg tacgccgtct gttccaaaat atttacccat agttgtaaaa ttactccttt
    16081 aacttaattt tctgaggaat ttgttctgct catttgtgtt gattcgcttg tttctgatgt
    16141 ttcttctgta cttgtggtcg agctgcttgt cccagattcc gaactggaag aaatggttgt
    16201 tgtcgatggt tccgttcctg aatcagcaga tgaaatactt ctactcgtac ttgtattttc
    16261 ttgtgtccga ctgctcgtcg aagcagagct actgcttgac gtttgcaaca cgggtgtaat
    16321 ctccacacta actgattcgg gcttgatact taacccctct tctactggta tttcaatttt
    16381 acgagttgtt cgatgattga tacctgagac attgatcggt acagcaatac tgtcaccgat
    16441 cgatgcaagc aaatcgctag agccgcttac ttctgcttcc agttttgaaa aactgaaatc
    16501 atagctttct accccggcag ctggtgttcc ttgctgtatc ccataaagtc gtaccgactt
    16561 gcttggcttg atcgaatcag ctctcactgt tacttgcact ggatcagaga cgatacttaa
    16621 tacttcccct gctgcattca gcgcctgtat tgggacctca ctattaatcc catcatctgt
    16681 gaccatcgaa gcgtccacat cagctactac tcgtttgatt tctgccaatg ttttgtcacc
    16741 tgtagtgata gagacttttt taggactaac ggaagtatca tcaagttcat atccagatgg
    16801 tgtgaacgtt gaaggaatca acgtttccac atcgaaatct tttattacct ttttctcaac
    16861 cgttactgta atagtcgatg gttcgatctt tgctgtgaca gcactgctca aattttgaat
    16921 ttttagcgga acttcatgtg ttccttcgcc cagcttagtg atatctgctg tgacgcggaa
    16981 catccgtgta tcttcgtttg cctctgcatt caactgaact cggtttgcac tggaaagttt
    17041 gacagtcact gcattttcat atccatggat atagtagcgc tttgaatcat aagaaatctt
    17101 gatcggcacc cccgtaactg tttgattata cgcttcattt ccagaaagcg tatttggaac
    17161 ggactggcca tttgcattga agtacagcgc aatactgaac agcaatgcaa taaaactgta
    17221 aagaatgctt gtccgtttct cttttgagat catttgcgat cccctccctt agtcataccg
    17281 tctaggaaag attgaatcac gtttttcttg ttttttgttt tctcttcagc aattagttct
    17341 ctacgcaaga ttgccaaata ttcttgctgg gataagccag ccatcagttc attatctaac
    17401 gtgatgctga cgtccccggt ttcttcagag acaacgatgg taatcgcgtc actgacttcg
    17461 cttataccga cagctgcccg gtgtcgagtc ccgaattctt tagggatcaa catactttct
    17521 gatagaggaa gataggcgct tgctactgcg atctttcctt cttttacaat aactgcaccg
    17581 tcatgcagcg gtgtattagg aataaagata ttgatcagca gctccccagt gatatctgca
    17641 tctaaagcaa tccctgtctc aatatactca tctaatccag tatgacgttc gatagtgatc
    17701 aacgcaccga tttttcgctt ggacatatat tggatggctt tgtcaaaaga caagatcatc
    17761 ttctcatctt cctgctgttc gctttttgat tgtttgaaaa gcgaactgcg tccaagatgt
    17821 tccagtcctc tccggatttc cggctgaaaa atcacgatag cagctatcac cccgtacgta
    17881 atgacttggt tcatcagcca agacaaggtg tgcagaccaa tgatttccgc tacgattcgg
    17941 ataacaataa aaatagctac acctttcaga agctgaatcg cttttgtgcc tcgcagcagt
    18001 tggatcagtt tgtatacaag ataccagaca accagaatat caagtatgtt caccaaaaaa
    18061 ttcagagaga acaagtcacc ggaaaacatt tgctgccaat agtccaaatt aaaaagttcc
    18121 ccgatttgaa atgacataaa aagcctctct tctcttttga gatttcctct ctagtatatc
    18181 atatgtttta attttagagg ctgatatgct cgtatttttc ttgagaaaaa cgcataattt
    18241 tcaagaaaat tgcaagtatg cgttttattt ttctctgcaa taaatatttt taaacttcag
    18301 agaattattc attatatttt ttctgttatt tttccttttt ttcttttgta gcttgttcca
    18361 tttttttacg tcgttctgct ctggcagctc ttctagcagc tcttctttct tctgcttcaa
    18421 ggtccgtcgt tttttctttt ctagtcttaa cgggtacatc gatagattcc tctggttcaa
    18481 gtcgtttctt gattttttct aattctcccg tcagtgcagc atagttgtaa aaacgtgttt
    18541 tagcgtcgtg gacagtcttt tcaaataaag cttttgcaag atttggattt gcgttatcta
    18601 gcgaggaaaa gcgaacttgt ttcctcatga aatcaggcat agcagagaaa tcaggttttt
    18661 tgtagtccaa agtcattggg ttcttgtttt tttcgaccat tgtagggtta tatcgatata
    18721 atgaccaata accagaagaa acagcttctt ttgcttcttt aagcgattct ttcattccgc
    18781 caagcaagcc atgtgtgata caaggcgtat aggcaataat cagagaagga ccaggatact
    18841 tttctgcttc ttcaaatgcc ttgatcgttt gcatttgatt ggcacctgaa gcaatttgcg
    18901 ccacataaac atttccatat gtcatcgcca tcattcctag atctttcttt gaagcatact
    18961 ttccactagc cgaaaattta gcgattgccg aagctggtgt tgcttttgag gtttgaccgc
    19021 cagtattgga atagacttcg ttatccaaaa caaggatatt cacgtctgct ccgctggcaa
    19081 gtacatgatc gatcccgcca aaaccaatgt cgtaagccca tccgtctcca ccaatcatcc
    19141 attggctgtt ttttacgaat agatcctttc tcttgtatat atcctccagt tcagggaaaa
    19201 ttgatcgttc gctttcgatc gcagcttgca gttttgctgc tctttgctgc gttccttcac
    19261 tctcaaacat gtgtactaac cagtcttcca tcaattctcg tagttcttct gatacttttg
    19321 gcaatacttc tttgattgaa cttgccaaag cctcgcgacg agtctgtgcc gctagaagca
    19381 taccataacc aaattcagca ttatcttcca ataaagaatt tgaccatgca ggcccttgac
    19441 cacattcatt ggtcgtataa ggagaagcag gagaagcacc gccccaaata gaagaacagc
    19501 ctgtcgcatt cgcgatcatc attcgatcac cgaacatttg tgtcaataat tttacataag
    19561 gtgtttcgcc acagcctgag caagcgcccg agaattcaag aagcggttga ttgaattgtg
    19621 tagacaagac agtattcttt cctttgactg gatttgcttt ttgtcttaat gtcattgcaa
    19681 aagcccaatt cacagcttgt tctttctgtt cttcataagg cttcatcact aaagcttttt
    19741 cttttgcggg acaagcctct acacacagac cacaacctgt acagtcttcc actgaaactt
    19801 ggatacggta ttttacgccg tctgcgcctc gcatttctct cacgataaat ccttctggcg
    19861 cttcttccat ttcctcttca tctgctaaaa atggacggat ggcagcatga ggacaaacaa
    19921 aggcacattc attacacatc gtacagcgat cactaatcca ctcaggtact tctaaagcga
    19981 cgccccgctt ttccatagaa gccgttccta aaggcatttc gccagttgtc attccatttg
    20041 ctacaagtgt accaacagag agttgatttc cttcctgtgc attcactggt tcaagtattt
    20101 cttgtatata accagtgttc cttttattga ttttttcagg catctccaac gttctccaat
    20161 ggtctgggat cgcgacttga tgaagcagtt cggtcgtccg atcgattgct tgtatgtttt
    20221 tttctacgat agccattgat ttatgtccat agcttttcag ggcttcttct tttagcagcg
    20281 gaagcacctc atcaaaagga atgatgtcag ctaatttaaa aaaagccgtt tccattgccg
    20341 tattgatccg gcgtcccaaa ccgacttctt gggccaatct catggcattg atcgtataga
    20401 atctaatgtt attttcagcc aagtaacgtt ttaattttaa gggcagatgc gtttctaatt
    20461 gttcgtcgct ccaaagagta ttcaataaaa aaatgccacc tggcttcaat cctttgacca
    20521 agtcatagct atgcaggtaa gctggtgtgt gacaggcaac aaggtccgca tgctcgacaa
    20581 gatacgctga acgtatcggc gtatctccaa aacgaagatg agagacagtc agaccgccag
    20641 attttttcga atcataataa aaatagcctt gcgcatattt atcggtgtga tctccaataa
    20701 tcttgatagc tgatttattt gctccaactg ttccgtcaga tccaaatccc caaaacttgg
    20761 cctggaatgt ttgcggttct gtcaaatcca gactttcctt tggttccaaa gattgataag
    20821 tcacatcatc cacgatccct atggtaaacc gttttttgcg tatgcttggg tcttttttca
    20881 attcatcaaa aactgctgag atttggtcgg gagtcacatc tttagacccc aatccgtagc
    20941 gaccaccaat aacagccggg cgaagttcag aatcatataa cgcactttga acgtctaata
    21001 agagaggttc tccacctgcc cctggttctt tacttcgatc aagaacagca attgttttta
    21061 ctgtatgagg caacttttgc acgaatgttt ccactggaaa aggacgataa agatggatat
    21121 tcaaaaaacc tgttttccgt ccgtttgcat tcaagtaatc aatcgtttgt tcaatcgtct
    21181 gtgcaactga tcccatagaa acaatgactt cttccgcatc gtctgctccg taataagtca
    21241 ccaagtcata agaagttcct cgtaatcggt tgatctcttt catatatttt tgaacgattt
    21301 caggtaattt atcataatag gggttgatcg tttcccgttg ttgaaaatgg atgtctggat
    21361 tctggttcgt accactaaca gtcggatgat tgggattcat ccctcgttta cgaaatgaag
    21421 ctaatttctc ctgattgatc agaggagcta attcttcata ttccaaaact tcgatttttt
    21481 gaatctcgtg actcgtacgg aatccatcaa agaaattcaa aaaagggact tctccttcaa
    21541 tagaagcaag atgggcaaca ggtgctaaat ccatcacttc ttgtacactg ctttcagcta
    21601 acatagcaaa tcctgtttgt cttgcagcca tcacgtctcc gtgatctccg aaaatattca
    21661 acgcatttgt cgtcactgcc cgactagcaa cgtggaaaac acttggcagt agttccccag
    21721 caatcttgta catattcggt atcatcaaaa gcagcccttg tgaagcggta tatgtagttg
    21781 tcagtgcacc agttttcaat gatccatgga ccacaccagc tgctcctgct tcggattgca
    21841 tttctactac ttttactggt tgaccgaata cgttttcttt tcctgctgct gaccattgat
    21901 ctactaattc agccatggtc gaactgggtg ttattggata tattgcagca atctcggtaa
    21961 atgcataaga aatatatgcg gctgccgtat tgccatccat tgttttcatt tttcgcatga
    22021 ttcatcatcc ttgttcatat tctctcttat tatctgttcc attataacgt aaaacatgcc
    22081 atttttttct tttatttata aaaatatttt acatgtatct atttgaattg gtcatctaat
    22141 ttttagacaa acagtctaaa tcgttgcctt tttttgtcag acatgtataa actataagcg
    22201 aaagaggtgt tttaacatgg atatatcagt gattgatgca acgaaaacaa atacacaaaa
    22261 aggaatcctt tatggttcat cgaatgctcc taaaaaaatg gtcgaattca tcaacttagc
    22321 ttgtccgtat tgccgacaat ggtttgaaga atcttatgag ctattagaag aagcagtcca
    22381 aagcgggcaa ttgcagcgag tgatcaaatt gttcgataaa gaaaaagaaa gcttacagcg
    22441 agggaacgtg atgcaccggt atctcacaat cagcgatggc caaaaagcga tcaaagagat
    22501 caaacaaata ttcgatactc aagacgagtg gaaacatctt tctctccaag aagtagcgga
    22561 ttttgcagta gataaactaa agctgacaga acaaaaagac gaacagctga gccaagctgt
    22621 catcaacgaa gctgagcaag cacatattcg atttgttcca actgtcatct tgggtaaaga
    22681 aatctttgat gaatctattt caatagagga attaaaagaa ttgatccaaa caaaataaaa
    22741 aaataaggag cgtgggacaa aagtaaagaa cacttttgtc tcacgctcta aacacgtata
    22801 aacggcggaa gcagaagcaa ctccttctta tttcttggag ttaaacgctt ctgtcccagc
    22861 ctccttattc cgaataaatg gtgtccaaaa gcttgcatct gccagattat ctcatttctt
    22921 atgacaagct aagcaaatta tctccaccaa ataatttatt catatttttg acttgcgcat
    22981 actaactaat tcttaaattt tcatacaaaa tttctcaatt tcccttaacg agtaatattt
    23041 atgtacggtg attctcacta gtatcccaat cactttttaa gttatcccga tttcaattct
    23101 acttcaaaaa tagttgcttt tatgtatgct gttagttgat tagatggtca tttgttgagc
    23161 taggtcgttt attttaaaca agttgtttct ttagcttata cctatctcgt ctaccaaacg
    23221 caagatggca aacacaaatg catacgcatc tgtatt
//
LOCUS       DAFBVQ010000044        23012 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.045, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000044 DAFBVQ010000000
VERSION     DAFBVQ010000044.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 23012)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 23012)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..23012
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.045"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(260..1492)
                     /locus_tag="LLC22_001877"
     CDS             complement(260..1492)
                     /locus_tag="LLC22_001877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminopeptidase"
                     /protein_id="HBK5435154.1"
                     /translation="MLSDFNELLKKYARLIAETGVATEKGHTVVLQISVEQAPLARLI
                     TQEAYKLGAAEVIVQWTDDQIQREFLLHAATDRIENVPQSKIDQADEWLEKGASRISV
                     VSADPDAFAGVDSHRVASYQSANGKALMNLRKATQANKVSWTVVAAAGKQWAAKVFPE
                     LPEEKQVEALWDQIFKTTRVYEEDPVLAWKKHDEKLAKKAEELNREQFSALHYTAPGT
                     DIIIGLPKNHLWEGAGSYNARGEKFMANMPTEEVFTAPDSHRVDGYISSTKPLSYAGT
                     IISGMKFTFKDGKVVDFSAEQGEDVLAKLLDTDEGARRLGEVALVPDPSPISQSGIIF
                     FNTLFDENASNHLALGSAYAFSVKGGTEMSDEELAEAGLNRSQTHVDFMVGSDKMDID
                     GIREDGSTVPIFRNGDWA"
     gene            1747..2316
                     /locus_tag="LLC22_001878"
     CDS             1747..2316
                     /locus_tag="LLC22_001878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339630.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5435155.1"
                     /translation="MARKKTITREQILAAAYEVAATDGFTRFTARNIANKMNCSTQPI
                     YLEFKNMDDLRQALFEQIYDHLQYEVFTVEHTGNTIIDLAFNYIHFARREKKLYRSLY
                     LEEYGGGKEMQNFSYTYFVNTVKRDPAYVNLSEEQIESLYNGTWIIATGIAALMSSSI
                     IHPTDEQIEKMIQDSIDAILKFKEPIEID"
     gene            complement(2494..2934)
                     /locus_tag="LLC22_001879"
     CDS             complement(2494..2934)
                     /locus_tag="LLC22_001879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flavodoxin"
                     /protein_id="HBK5435156.1"
                     /translation="MALAKIVYASMTGNTEEIADIVAEAFENLDIEVEINECTQVDAD
                     EFEEADICVVATYTYDDGDLPDEIVDFYEDLQELDLLGKIYGVCGSGDTFYDEFCKSV
                     DDFDAAFAKTGASKGAENVKVDLNAEEEDIENLEAFAKELVAKI"
     gene            3092..3856
                     /gene="map"
                     /locus_tag="LLC22_001880"
     CDS             3092..3856
                     /gene="map"
                     /locus_tag="LLC22_001880"
                     /EC_number="3.4.11.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008377375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I methionyl aminopeptidase"
                     /protein_id="HBK5435157.1"
                     /translation="MITLKSAREIEMMAESGALLADVHKNLRDFIKPGITSWDIEVFV
                     RNYIESHGGIAAQIGFEGYEYATCISINDEICHGFPRKKPLKNGDLVKVDMCIDLKGG
                     ISDSCWAYVVGESTPEIDRLMEVTKKALYIGIEQAQVGNRIGDIGHAIQTYVEGENLA
                     IVRDFIGHGVGPTIHEEPAVPHYGEAGKGLRLKEGMVITIEPMVNTGTWKMKMDPNGW
                     TAYTRDGGLSCQYEHTLAITKDGPRILTSQGEEGTY"
     gene            3888..4811
                     /locus_tag="LLC22_001881"
     CDS             3888..4811
                     /locus_tag="LLC22_001881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330638.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YihY/virulence factor BrkB family protein"
                     /protein_id="HBK5435158.1"
                     /translation="MKVWNKIKQNENLMRFIETTQKRITDSEMSTTSVVVAYYLLLSL
                     FPLIIAFGNILPFLHIDQETVLTYLREVIPETVYQFIGPAIKDLLTQSSGGLLSVSAL
                     AALWSASQSINALQIAMNKAYGVENRKNFLIVRFFSLIVIVLFMIAISGVTIVLGLGQ
                     LILDAIQPIVQIPVNFIDQFQTLKWPITLVALFVIMFLIYLIVPNAQLKLKTIIPGTI
                     FATVGWMLLSQVFSIYARYFATRISGYQIIGSFIVLMLWLNFAATIIILGGIINAVVQ
                     EYVTGHQIKKRRDPSRKWFNKLKTKFSHKKK"
     gene            4887..6026
                     /locus_tag="LLC22_001882"
     CDS             4887..6026
                     /locus_tag="LLC22_001882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329034.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="undecaprenyl/decaprenyl-phosphate
                     alpha-N-acetylglucosaminyl 1-phosphate transferase"
                     /protein_id="HBK5435159.1"
                     /translation="MLVSFSMVIRFFLTILLSLILTPVFKIISVQTGMVDKPNERRIN
                     KVPMPSAGGLPIFISFVISTLFLFRKIIPQSYIVPILIASLVIIVTGVLDDKYELTPK
                     QKSIGILIASLIIYFVADIRIDSFTLPFIGYIQLGWLSFPVTIFWIFGITNAVNLIDG
                     LDGLAAGISLIGLITIGIIGYFFLHASTVYIPVVIFCLVASIIGFFPYNFYPAKIYLG
                     DTGALFLGFMMAVLSLQGLKNVTFVSSISLLIVMGVPVTDTFFAIIRRKANRVSFSTA
                     DKKHLHHRLISLGFTHKGAVLTIYAMALMFSFTAMVMNYTGRIGTIILIIAMLFAAIL
                     LFELIGLINEKHQFILKTLRFLGNKEYRTQVKQKYLKKWNRHIDE"
     gene            6019..6819
                     /locus_tag="LLC22_001883"
     CDS             6019..6819
                     /locus_tag="LLC22_001883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346778.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5435160.1"
                     /translation="MNNKLNQPILISIVTANSDKIFRTLDNFISTVKDETAVKIRIFD
                     NNSLPEYKKRLTEYRKYPYIDIYFHDENSGFGYGHNHNLIASDSRYGIICNPDILVDE
                     ETVTALVLLLKEHPECAMLAPKILNEDGTTQHLIREQLAVFDYVLRFVPFKWVKKKFD
                     KRLAVFECRGLPTDANSYVRMISGSFMVADIDKFKEIKGFDERFFMYFEDNDLCLSFE
                     KAGYKLLYTPFYAVIHFYGKGAHRNAKLFRVFLTSMMKFFNKWGWRFF"
     gene            6819..7646
                     /locus_tag="LLC22_001884"
     CDS             6819..7646
                     /locus_tag="LLC22_001884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377110.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5435161.1"
                     /translation="MKPEILVVVVLYQQLFSQSPAYGPLSKALSEKPIQLIIYDNSPQ
                     RQQNELFEKENIVYHHDPQNPGLAVAYNFALSQADEGTRCLVTLDQDTRLVDDYFELL
                     RKVTFTDECVAAVPMIFSGSRQVSPLYSDRYINRTAQAVEVEGPTAERIMAINSGVAW
                     SVKFLKKIGGFNPAFSLDFLDHWLFWKVDQLEKTVEILPVRMEHDLSVLDYEKVSSNR
                     YRSILQAENRFYHEYDQRHLSSHRRQLLLRTAKQFLTVKNRHIWRMTLRSYVKNWKV"
     gene            7624..8358
                     /locus_tag="LLC22_001885"
     CDS             7624..8358
                     /locus_tag="LLC22_001885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5435162.1"
                     /translation="MLRIGRCEFVRSVCIATFNGGRYLREQLDSILSQLSAEDEVVIS
                     DDGSVDDTWDILTEYAEKDKRIQLFSGPRQGLIANFGYAIQQTKGDLIFLADQDDVWL
                     ETKVKKITDYFEQNPDQLVVVSDLIIVDSELQEIHDSYFSFRNSKEGWLNNVIRSHYI
                     GAGMAFRSSLKPDILPIPSEVPMHDMWIGLLGGKKTGFLREPLTLYRRHDLNASEIET
                     HSKLRQKISWRVHLITALIKRKWFKR"
     gene            8458..9324
                     /gene="rfbA"
                     /locus_tag="LLC22_001886"
     CDS             8458..9324
                     /gene="rfbA"
                     /locus_tag="LLC22_001886"
                     /EC_number="2.7.7.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735945.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-1-phosphate thymidylyltransferase RfbA"
                     /protein_id="HBK5435163.1"
                     /translation="MKGIILAGGSGTRLYPLTKATSKQLMPIYDKPMIYYPMSTLMLA
                     GIKEILIISTPQDTPRFKELFGNGNDLGLQIEYAVQESPDGLAQAFIIGEEFIGDDSV
                     CLVLGDNIYYGGGLSKMLQRAASKDTGATVFGYHVNDPERFGVVEFDENMQALSIEEK
                     PAQPKSNYAVTGLYFYDNEVISIAKGIKPSERGELEITDVNKAYLDKGKLSVELMGRG
                     FAWLDTGTHESLLEASTFIETIEKRQNLKVACLEEIAYRMGYIDKEQLLALAQPLKKN
                     QYGQYLLNLAAE"
     gene            9338..9910
                     /gene="rfbC"
                     /locus_tag="LLC22_001887"
     CDS             9338..9910
                     /gene="rfbC"
                     /locus_tag="LLC22_001887"
                     /EC_number="5.1.3.13"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010771301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose 3,5-epimerase"
                     /protein_id="HBK5435164.1"
                     /translation="MKVTDTKLTDVKIVEMDVFGDHRGFFTESYSKAKFAEHGLKYDF
                     VQDNHSLSAEAGVLRGLHFQKGEAAQTKLIRVVTGAVLDVVVDIRKGSPTYGQWDGFI
                     LSEHNHRQLLVPKGYAHGFVTLTPNVNFLYKCDNYYNAEADGGIAFDDPDLAIDWPID
                     PSRAIMSEKDHRHPTLKEFEAENPFVYGEI"
     gene            9932..10960
                     /gene="rfbB"
                     /locus_tag="LLC22_001888"
     CDS             9932..10960
                     /gene="rfbB"
                     /locus_tag="LLC22_001888"
                     /EC_number="4.2.1.46"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719743.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-glucose 4,6-dehydratase"
                     /protein_id="HBK5435165.1"
                     /translation="MKNIIVTGGAGFIGSNFVHYVVNNHPEVHVTVLDKLTYAGNKEN
                     LAGLPSDRVELVVGDVADAELVDRLVKEADAVVHYAAESHNDNSLKDPFPFVQTNIIG
                     TYTLLEACRKYDVRYHHVSTDEVYGDLPLREDLPGHGEGEGEKFTAETPYNPSSPYSS
                     TKAGSDLLVKAWVRSFGLRATISNCSNNYGPYQHIEKFIPRQVTNILSGIRPKLYGEG
                     KNVRDWIHTNDHSSAVWLILTKGRIGETYLIGADGEEDNKTVMELILEMMGQPKDAYD
                     HVNDRAGHDLRYAIDSTKLREELGWKPEFTNFRDGLADTIKWYEEHEDWWKKEKEAVE
                     AAYAKNGQ"
     gene            11058..11909
                     /gene="rfbD"
                     /locus_tag="LLC22_001889"
     CDS             11058..11909
                     /gene="rfbD"
                     /locus_tag="LLC22_001889"
                     /EC_number="1.1.1.133"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dTDP-4-dehydrorhamnose reductase"
                     /protein_id="HBK5435166.1"
                     /translation="MFLLTGGNGQLGTELRHLLDEKNLQYVSTDAKDLDITDAEKTMA
                     YITELKPDVIFHCAAYTAVDKAEEEAKELDEKINVDGTRNVALAAKAVNAQFVYISTD
                     YVFDGKNKNVEYEVDDQTNPLNEYGRTKLLGEKAVEEILEDYYIIRTSWVFGIYGHNF
                     VFTMQRLAETRDKLTVVNDQFGRPTWTRTLAEFMVYVIEEKAPFGIYHLSNENSCSWY
                     EFAKEILKDTDVEVAPVTSEEFPQKATRPQYSVMSLKKTEELGFVIPTWQEALAQMLE
                     AAKKMNK"
     gene            11943..13976
                     /locus_tag="LLC22_001890"
     CDS             11943..13976
                     /locus_tag="LLC22_001890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377112.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435167.1"
                     /translation="MEKQTRSARRKEKPKANQADSNLVLDLFLKLRYLIGVLVIVVIV
                     TFNLNGSSLGVWDKYVSQRDDGKKTDVIFGQNREVRSDEWLVQTPFYLSQAEEDFPLV
                     NEDYSLNGQNMIIAYNSPVKDITVIGKPFNWGFFFLGRDRGLSFYWAMKLVVMVLLGF
                     EVLMILTKRKKALSLIGAFALTFSPAVQWWFMQHVGDLIFFTLGLMTAFYHYFYNHDK
                     KWLRTLMMLLVVIFGIGFILVIYPAHQVMLAYLLIFYFVGLLIYYSKKVSWDLLDVVL
                     IGGAVLFIGGVMVHFWLTSKDALLASLNTLYPGKRVSTGGKWTIGEFFSFLTNWKIPF
                     EDINYSNNSEVALFYHFFPTVFLASPFVLFGKKDSEQKLLGRILMIFCLFSIFWITVG
                     LPKWLAEITLLSYVPPLRAILTFSFAACLLSIWFIAYIWREDVIPIWYKFILLAVNAW
                     SYFYAITHSKMDNYFSDFETIAVAVLGTVILAFALFGWRRLFYLAFAALVIVSGFFVN
                     PVVEGTGAIFEKTLAKEIQKIDQQDPGKVWLSEDELYNFTPTLGVKSFNTVRFYPDIA
                     AWKKIDPKEEYEKYYNRYAHTRAFIAKEDTKFILDRPDMFSVTLNFEDAEKLGIDYVI
                     SKRPLTDYNQLYEAQFTQLYGPDKDGYMIFKVEYPDYPDVPQTQTQENQLVVQ"
     gene            14020..15299
                     /locus_tag="LLC22_001891"
                     /pseudo
     CDS             14020..15299
                     /locus_tag="LLC22_001891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377113.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="EpaQ family protein"
     gene            15509..16315
                     /locus_tag="LLC22_001892"
     CDS             15509..16315
                     /locus_tag="LLC22_001892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435168.1"
                     /translation="MFKDLYLFMKDIYQNRKLLLQFSINDFKSRYAGSFLGILWAFIN
                     PLFTVLIYWLVFGVGLKAQMIDAKYPFIVYLVTGMIPWFFFSDAFASTTVVFREYTYL
                     VKKVVFNIRILPTTKILSNLYTHLFFILIGIAVALINGIYPSAMSLQLIYYLFCMCAF
                     LTGLTWLTASIQPFLPDIMQLITIVLQLIMWTLPILWSPNQFDSGLVSILKLNPLYYV
                     VQGYRESFLSEAWFWEHGTYTLYFWVFTLVMFVIGSAVFRRLKPHFSDVL"
     gene            16327..17547
                     /locus_tag="LLC22_001893"
     CDS             16327..17547
                     /locus_tag="LLC22_001893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435169.1"
                     /translation="MTEYAIRLKDITKSYNMYAKPSDRFREALNPFKKSYHDVFYALK
                     NVNVEIKKGEMIGFVGENGSGKSTMLKIITGVLTPTSGTMEIEGKISALLELGSGFNP
                     EYSGYENIYLNGMVLGFSREEVDEMVDDIIEFADIGDHIYQPVKTYSSGMFVRLAFAV
                     AINVNPDILIVDEALAVGDLEFQLKCMEKFTEIKNSGKTILFVSHDISSIRRFCDRSY
                     WLKNGEVVEYGDTMEVTTNYENFLKKKSVKTVDRNKNQVERFAAPDIVDVTKAELLDK
                     DKNPVDMLEQGEKLYVKVTYEVKDDTIKNPVLGIALRTVDNFYVCGLNTLLDGIKIPW
                     KKGENIFYLEYEKLGLLAGEYYFDVAVFEENATVPLVYKTKYMNLFVSGSYIGEGIVV
                     LDHKWEEGTHSNEI"
     gene            17537..19123
                     /locus_tag="LLC22_001894"
     CDS             17537..19123
                     /locus_tag="LLC22_001894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5435170.1"
                     /translation="MKYDFEMDLDEQSSVGKIAAQIKPGSKVLEFGPGNGRLTKHLIG
                     AKQCEVSIVELDKELFDFVSEFAQDGFYGDIESFEWANYYAGQTFDYVLFADVLEHLV
                     DPGKTLKKVREFLNEEGEILITFPNLAHNSVMIDLFNNQLPWASYGLLDETHNSFYTH
                     DGFQKVFEKAGLFINIEDYLYLAVGDTELKSTYEELPEAVRYDFKMRPFGEVYQYFFS
                     LMKHPVAQSSIAEPQNSNYVKVLEVTQQTKQDETIQQIPFNNFTGENETLSFPVSETT
                     ERMVFRFAQQPSFIEFSAEAAGEKLTFIDSNAVVKTVNDCYLFDGKELPEFVLTDISG
                     KEVTIHCHYRFIGELTPTMKELLETIRPMAEVTKQLSEKNDELERENHHLLEENTRLD
                     HTLKTTTNRYCTLLESDEWTIKHRLGRRKKETSKKIQEKELSICIDEKIWDAETKILK
                     IIGWGIANSDRQPLSYKLSADQSPFFEAIPVSREEVNQAEQLAKGTEAGFELRILCEQ
                     ERSFLVEAVAQNGQSWIIEM"
     gene            19162..21300
                     /locus_tag="LLC22_001895"
     CDS             19162..21300
                     /locus_tag="LLC22_001895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328200.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5435171.1"
                     /translation="MQKKEIAVFIDQITRERATGDLLIVGWAIDEVTKEIPTIKVEKE
                     NVIAEATHVVRLDINHLYNLDVKTQSGFKVRLSGKMRGKAILDFQTARHQNGIAVKLN
                     GKYPYDDGIESSWERKKRLLKKGINYARTHGVKKAIRRVKLELKPGSIDYAEWISRHE
                     KPDLKEQRKEAQGFAYRPLISILMPVYNVEIKWLEKCIDSVLDQTYDHWELCISDDAS
                     TDPAIRKCLESYQAKDDRIKVVFRKENGHISLATNSALEIAEGEFIALLDNDDELPPF
                     ALYEVAKVLNVHPELDVIYSDEDKIDADGNRFDPHFKADWSPDTLMGNNYISHLGVYR
                     TSIVKELGGFRKGYEGSQDYDLVLRVTEQIPADHIYHIDRVLYHWRTIPGSTASNGEA
                     KSYIYDSGVKALTDALSRRNIKGSVRPGRISGFYEIAYDVLQEDLVSVIIPTKNGYED
                     LKTCVDSIIEKTSYSNYEIIIADNGSTDPKMQELFAEYKHQLKDRFIVELIDIPFNYS
                     RINNLAAEKANGKYFLFLNNDTEVIEPDWMTVMVSYAQFDRIGCVGAKLFYPDDTTQH
                     AGVLLGIGGVAGHALNNYDRTHCGYFGRLVIDVNYLAVTAACMMVKAADFNAVNGFDE
                     TLEVAFNDVDLCLKVYELGRYNVYAHQAELYHFESKSRGYEDTPEKQRRFAGEIKKMQ
                     DKWPAYIAHDPFYNDNLTKEGIGDFSLRPD"
     gene            complement(21668..22651)
                     /locus_tag="LLC22_001896"
     CDS             complement(21668..22651)
                     /locus_tag="LLC22_001896"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine hydrolase"
                     /protein_id="HBK5435172.1"
                     /translation="MNKQELHDFIGFRQPNICQIVAYKDGVEVYTDEWNGYKKDDTCH
                     IMSATKSIVSLLIGIALEQGLIKSIDDKVLDYFPEYKVKRGEKTIYAITIKHLLTMKA
                     PYKCKGDPWTKVCSSEDWTKTSLDLLGGRKGITGEFNYQTVCLHILTGLLYQTSKLTT
                     VDFANKYLFDPIGIPNHVNYYAETAEEHKQFTMDKSPKTNVWFCDPLNIGTAGYGLCL
                     SASDLAKIGVLCLNKGMYKGKQIVPPMWINEMFKPRTSALEDLQNMRYGYLWWVLDSE
                     NEIYSAIGNSGNVLYIDAKNNLVISITSYFKPMIIDRVAFVEEYLKPFILK"
BASE COUNT         7216 a         3935 c         4747 g         7114 t
ORIGIN      
        1 cgagtctctt ctttctgagg agagacatca agagtcgctg cgctactgct cctgacctct
       61 ctcctcagaa agaaaggcat ggcagttagg ttcacaacgc aaaacattgt gcttttgatg
      121 aggttgaact tttacacaag attgtggact tgactaaaaa aacggtgggg ttgtttagcg
      181 aaataaagga tctaagccaa tagcttagat cctttattct atgctttata ttattttttg
      241 catgtgtgcg aaagtatact caagcccaat cgccatttcg gaaaatcggt actgtagagc
      301 catcttcacg gattccgtcg atatccatct tgtcagatcc taccatgaaa tctacgtggg
      361 tttgacttct attcaatcca gcttctgcta attcttcatc ggacatttct gtaccgcctt
      421 tcacactgaa ggcataagca gaacctagtg ctaagtgatt cgatgcgttt tcatcaaata
      481 atgtattgaa aaagatgatg ccagattgag aaataggtga agggtcaggt acaagtgcga
      541 cttctcctaa acgacgcgca ccttcatctg tatcaagcag ttttgctaag acatcttctc
      601 cttgttcggc agaaaaatca acaacttttc catctttaaa agtaaatttc atacccgaga
      661 tgatggtgcc agcataactc agtggctttg tacttgaaat gtaaccatct actcgatgac
      721 tgtcaggtgc tgtgaacact tcttccgtcg gcatatttgc catgaatttt tctccacgag
      781 cattatagct tccagcgcct tcccaaagat ggtttttagg caatccgata atgatatctg
      841 taccgggagc agtatagtga agggcagaaa attgttctcg attcaattct tctgcttttt
      901 ttgctaattt ttcatcatgc ttcttccatg ctaagacagg gtcttcttca tagacacgag
      961 tcgttttgaa aatctgatcc cataatgcct caacttgttt ttcttctggc agttctggga
     1021 agacttttgc tgcccattgt ttaccagccg cagccacgac agtccaactg actttatttg
     1081 cttgagttgc cttgcgtaaa ttcattagtg ctttgccatt cgctgattga taagacgcta
     1141 ctcgatggct atctacacca gcaaatgcat cgggatcggc agaaacaacg ctgatcctgc
     1201 ttgctccttt ttcaagccat tcatccgctt gatcgatttt agattgtggt acattctcaa
     1261 tacgatccgt tgcagcatgt aaaagaaatt ctctttggat ctggtcgtca gtccattgaa
     1321 cgataacctc agcggctcct agtttataag cttcttgtgt gatcaatcga gcaaggggtg
     1381 cctgttccac gctgatctgt aaaacaactg tgtgtccttt ttctgtggct acgccagttt
     1441 ctgcaattaa gcgtgcatat ttttttagaa gttcattaaa atcagataac ataataaaaa
     1501 ttcctcctca ccattttttc tggtaactat tagcatgata ccatttaatt atgattcaaa
     1561 caatgaggct ttaaataaaa aaaggaggtt atttttttaa ggttaagttt catgatatat
     1621 gttactactt gctatttcag cttgtgaaga aaatcaaaaa ctaattttgc atatcaaaaa
     1681 aaacatgtta caatgaaatt aatcaatggt ggaagcgtta taaaaaaatt aaggagatta
     1741 aaaaatatgg caagaaaaaa gacgattact agagaacaga ttttggcagc tgcttatgaa
     1801 gtagctgcca ccgatggatt tacacgattt actgcgagaa acatcgcgaa caaaatgaat
     1861 tgttccacgc aaccgattta tcttgagttt aaaaatatgg atgacttgag acaagctctt
     1921 tttgagcaga tctatgatca tttacaatat gaagtgttca ctgttgagca tacagggaat
     1981 acgattatcg atcttgcttt taattatatc cattttgcaa gaagagagaa gaagttgtat
     2041 cgttcactgt acttagaaga atatggtgga ggaaaagaga tgcagaattt ctcttatact
     2101 tactttgtga atacagtgaa acgcgatcca gcttatgtga atctttcaga agagcagatc
     2161 gaatctttgt ataatgggac atggatcata gctactggga tcgcagcttt gatgtcttca
     2221 agcatcatcc atccaactga tgaacagatt gaaaagatga tccaagacag tatagatgct
     2281 atcttgaaat tcaaagaacc aatcgaaatc gattgaatat actcaaaagt tccacaaatc
     2341 agtaggtaac aagagatgtg tcaaaataag gaaaagttcg tttttcttac agcgtatgca
     2401 tttttaactc ccgaagaact cttccatgaa tgcaatgaat aaaagagcca tacagattga
     2461 ataaatctgg atggctcttt tattgcaagt atattaaatt tttgcgacta gttctttagc
     2521 gaaagcttct aaattttcga tatcttcttc ttcagcattc agatccactt taacattttc
     2581 ggctcctttt gatgcgcctg tttttgcaaa agcagcatcg aaatcatcca ccgatttgca
     2641 gaattcatcg taaaaagtat caccagatcc gcagacaccg taaatttttc ccaatagatc
     2701 caattcttgc aagtcttcat aaaagtctac gatctcatca ggcagatcgc catcatcgta
     2761 tgtataagta gctactacgc aaatatctgc ctcctcgaat tcatctgcat ctacttgggt
     2821 acattcgttg atttcgactt cgatatccag attttcaaat gcttctgcaa caatatcggc
     2881 gatttcttca gtgtttcctg tcatgctagc atatacgatt tttgctaaag ccatgatgtg
     2941 cctcctcgtt tataattatt taacaattat gaattatacc aaaacatcat tgaaaagaaa
     3001 ataaaaccta gagacacctg gggaatgtca tttggctaaa tgtatgccgc tatgttaaaa
     3061 tgagagggat ttgtaaaaag gagacgaaaa tatgattact ttaaaatcag cacgtgaaat
     3121 tgaaatgatg gcagaatctg gagctttatt agcagatgta cataaaaatc tgcgtgattt
     3181 tataaaacca ggaatcacaa gttgggatat tgaggtattt gtcagaaact atatcgagag
     3241 tcatggcgga attgctgcgc aaattggctt tgaagggtat gaatatgcga cttgtatcag
     3301 tataaatgat gaaatttgtc atggattccc tcgtaaaaag cctttgaaaa acggtgattt
     3361 ggtaaaagtc gatatgtgta tcgatttgaa aggcggcatt tctgattctt gttgggccta
     3421 tgtagttgga gaatctacac ctgagatcga ccgattgatg gaagtaacga agaaagcttt
     3481 gtacatcggt attgagcaag cacaagtagg gaatcggatt ggtgacatcg gtcatgctat
     3541 ccaaacttat gtagaaggcg aaaatctagc gatcgttcgt gattttattg gtcatggcgt
     3601 tggtcctacg attcatgaag aaccagcagt tcctcattac ggagaagctg gaaaagggtt
     3661 gcggttgaaa gaaggcatgg ttatcacgat cgaacctatg gttaataccg gaacttggaa
     3721 aatgaaaatg gatcctaacg gctggactgc gtatacaaga gacggcggac tttcttgcca
     3781 atatgaacat acattggcta ttactaaaga tggtccaaga attttgacat cacaaggaga
     3841 agaaggcact tattgatcta tccagtcaat aggtacggga gaggtacatg aaagtttgga
     3901 acaaaataaa acaaaatgaa aatctgatgc gctttattga gacgactcaa aagcgcatca
     3961 ctgattcaga aatgagtacg acctctgtcg tcgttgctta ttatttactc ttgtctttat
     4021 ttccattgat tattgctttt ggtaatattt taccgtttct ccacatcgat caagagactg
     4081 tactgaccta tttacgagaa gtgattcctg agaccgttta ccagtttatc ggtcctgcaa
     4141 tcaaagacct tttgacacaa agttcaggag gcttgttatc cgtttctgca ttagcggctt
     4201 tatggtctgc aagtcaaagt atcaatgctt tgcaaattgc gatgaataaa gcgtatggcg
     4261 tagaaaatag aaaaaatttt ttgatcgtcc gtttcttctc actaattgtc attgtcttgt
     4321 tcatgattgc tattagtggg gtaactatcg ttcttgggtt gggacagctg attttggatg
     4381 ctattcagcc aatcgtacaa atacccgtga actttatcga tcagttccaa actttgaagt
     4441 ggccaatcac attggtagct ttatttgtca tcatgttctt gatttattta attgtcccta
     4501 atgctcagtt gaagttgaag acgatcattc cgggcacgat cttcgctact gtcggctgga
     4561 tgctgttatc acaagtgttt agtatctatg ctaggtattt tgcaacgagg atcagcggtt
     4621 atcagatcat aggaagtttt attgtactca tgctttggct taattttgct gctacgatca
     4681 tcattttggg cggaatcatc aatgcagttg ttcaagaata cgtgacgggt catcaaatca
     4741 aaaaacgtcg agatccaagc cgaaaatggt tcaataaatt gaaaactaaa ttttctcata
     4801 aaaaaaagta gaaacaagag ttcttattgt aaatttatat cagtaattta taataattat
     4861 gactcttaat taaagtaggt gcccatatgc ttgtttcttt tagtatggtt ataagatttt
     4921 ttctgacaat tttattatca ctgatattaa cacctgtatt caaaatcatt tcagtacaaa
     4981 caggtatggt cgacaaacca aatgaaagaa gaataaataa agttccaatg ccttcagcgg
     5041 gcggactgcc tatctttatt tcatttgtta tatcgacttt attcttattc cgtaaaatta
     5101 tccctcaatc gtatattgta ccgatcttga ttgcttcttt agtaatcata gtcacaggag
     5161 tgctcgatga taaatatgag ctgacaccta aacaaaaaag tatagggatc ttgattgctt
     5221 ctcttattat ttattttgta gcagatatac gtattgattc cttcacgctt ccttttattg
     5281 gatatatcca actaggctgg cttagttttc ccgtaacgat tttttggatc ttcggtatca
     5341 cgaatgcggt caatctgatt gacggtttgg atgggctggc ggcagggatt tcattgatcg
     5401 gtttaattac gataggaatc attggatatt ttttcctcca tgcttctaca gtgtatattc
     5461 cagttgttat tttctgtctt gtagcaagta ttatcggttt ttttccttac aatttttatc
     5521 cggcaaagat ttatttaggc gatacaggag ctctattcct agggtttatg atggccgtcc
     5581 tttcactaca agggctgaag aacgtgactt ttgtttcatc gatttctttg ctgatcgtca
     5641 tgggagtgcc ggtaacagac acgttttttg ctatcattag gagaaaagca aaccgtgttt
     5701 ctttttctac agcagataaa aaacatcttc atcaccgact aatcagttta ggctttactc
     5761 ataaaggtgc tgtcctgacg atttatgcga tggctttgat gttttctttc acagctatgg
     5821 tcatgaatta tactggaaga atcggaacga tcatattgat tattgccatg ttgtttgctg
     5881 caattttatt atttgaattg attggtctga tcaatgagaa acatcagttt attttaaaaa
     5941 cattgcgatt tttagggaat aaagagtacc gtacgcaagt aaaacagaaa tatttgaaga
     6001 aatggaaccg tcatatagat gaataacaaa ttaaaccagc cgatccttat tagtattgtg
     6061 acggcaaaca gtgataaaat ttttcggaca ctagataatt ttatttcaac tgtaaaagat
     6121 gaaacagcag taaaaatccg aatttttgac aacaattcac ttcccgagta caaaaaaaga
     6181 ctaacagagt ataggaaata tccctacatc gatatctatt ttcatgatga aaattccgga
     6241 tttggttatg gacataatca caatctgata gctagcgatt ctcgctatgg cattatttgt
     6301 aacccagata ttttagtgga tgaagagaca gttacagcat tggtcttgtt attgaaagaa
     6361 catccggaat gtgcgatgtt agcacctaag attcttaatg aagatggaac aactcagcac
     6421 ctcatccgtg agcagctggc tgtttttgat tacgttttgc gctttgtgcc tttcaaatgg
     6481 gtcaaaaaaa agtttgacaa acgactggct gtgtttgaat gccgaggatt gcctactgat
     6541 gctaatagtt atgtacggat gatctcaggt agttttatgg tagctgatat tgataaattt
     6601 aaagagataa aggggtttga tgagcgtttc ttcatgtact ttgaagacaa cgacttgtgt
     6661 ttgagttttg aaaaagcagg ttacaagtta ttgtacacac ccttttatgc agttatccat
     6721 ttttacggga agggtgcgca tcgaaatgca aaactgtttc gcgtgttttt gacttctatg
     6781 atgaaatttt tcaataagtg ggggtggcgt tttttctgat gaaaccagaa atattagtag
     6841 tcgttgtgct ttatcagcaa ctattcagtc aatctccagc ttatggacca ttaagcaaag
     6901 cacttagcga aaagccaatt cagcttatta tttacgataa tagtcctcaa aggcagcaaa
     6961 atgagctgtt tgaaaaagaa aatatcgttt atcatcatga tccgcaaaat cctggtttag
     7021 cggtggctta taattttgcg ttgtctcaag cagatgaagg aacacgttgt ctcgtcactc
     7081 tggatcagga tacgaggcta gtcgacgatt attttgaact attgcgtaaa gtaaccttta
     7141 cagatgaatg tgttgctgca gttccgatga ttttttctgg gagccgacaa gtttctcccc
     7201 tatattcaga tcgttatatc aatcgtacag ctcaagcagt agaagttgaa ggcccaacag
     7261 ctgaacgaat catggcaatc aattcaggtg ttgcctggtc tgtcaaattt ctaaaaaaga
     7321 ttggcgggtt taatcctgct ttttctttag attttttgga tcattggctg ttttggaaag
     7381 tggatcagtt ggaaaaaact gtggagatcc ttcctgtacg aatggaacat gatctttcgg
     7441 ttttagacta tgaaaaagtt tcaagtaatc gataccgttc tattttacaa gcagaaaatc
     7501 gattttatca tgaatatgat caaaggcatt tatccagtca ccgacgacaa ttattgttaa
     7561 gaacagctaa acagttcttg accgtcaaaa accggcatat ctggcggatg actttgcgct
     7621 catatgttaa gaattggaag gtgtgaattc gtgcgttcgg tttgtatagc tacctttaat
     7681 ggaggcagat atttaagaga gcagttagat agtattttat ctcagctttc agcagaagat
     7741 gaagtagtca tttctgatga tgggtcagta gatgatacat gggatatatt aactgaatac
     7801 gcagaaaaag ataagcgaat ccagcttttt tcggggcctc gtcaaggatt gatcgctaat
     7861 tttggttatg cgatccagca gacgaaagga gatctaatct ttttggcaga ccaagatgat
     7921 gtttggttgg agacaaaagt gaaaaagatc actgactatt ttgagcagaa tccggatcag
     7981 ctagtagtag tttctgattt aatcattgtg gacagcgagc tgcaagagat ccatgattcg
     8041 tatttttcgt ttcgaaattc caaagaagga tggcttaata atgtgataag aagtcactat
     8101 attggtgctg gtatggcttt ccggtcttct ttaaaacccg atattttgcc gatcccgtca
     8161 gaagtgccga tgcatgatat gtggattggt ttgctgggag gaaagaagac tgggttccta
     8221 agagaaccgt taactctgta ccgaagacat gatttaaacg cgagtgagat tgaaacacat
     8281 tctaaattac ggcaaaaaat ttcttggcgt gttcatctga ttacggcgtt gatcaaacga
     8341 aaatggttta aacgttgata aaagatgttt aaatccttaa tatttccatg acaaatataa
     8401 caattgatga gataataaca aagtgaaatt tgaaatcaaa aaggagagca gatatccatg
     8461 aagggaatca ttcttgctgg gggcagcgga acacgtctgt accctttaac aaaggcaaca
     8521 tcgaaacaat tgatgccgat ttatgacaaa ccaatgattt attatccaat gtctactctg
     8581 atgttggcgg gaatcaaaga aattctgatt atttcaacgc cacaagatac accacgtttc
     8641 aaggaattat ttggaaacgg aaatgattta ggactgcaga tcgaatatgc agtacaagaa
     8701 agtccagatg gattggcaca agcgtttatc attggagaag aatttattgg agatgatagt
     8761 gtctgcttgg tattagggga caatatttac tatggtggcg gtctgtctaa aatgttgcaa
     8821 cgagcagctt caaaagatac aggcgcgaca gtatttggct atcatgtcaa tgatccagaa
     8881 cgctttggtg tagtagaatt tgatgagaat atgcaagctt tgtcgattga agaaaagcct
     8941 gctcagccaa aatcaaatta cgctgtaact ggcctttatt tttatgacaa tgaggtaatt
     9001 tctatcgcta aaggtatcaa accttcagaa cgtggagaac tagagattac ggatgtcaat
     9061 aaagcatatt tggataaagg aaaactatcc gtagaactta tgggacgcgg atttgcttgg
     9121 cttgatacag gaacacatga atcattgctt gaagcatcta cctttatcga aacaattgaa
     9181 aaacgtcaga acttaaaagt ggcttgtttg gaagaaattg cttaccgtat gggctacatc
     9241 gataaggaac aattgctggc ccttgcacag ccattgaaaa aaaatcaata cggtcaatat
     9301 ttattgaatt tggccgctga ataaggagtc cttacagatg aaagtaacag atacaaaatt
     9361 aacagatgtc aaaatcgtag aaatggacgt ctttggcgat catcgcggtt tcttcacaga
     9421 aagttattca aaagcaaaat ttgcagaaca tggattgaaa tatgactttg ttcaagacaa
     9481 ccattcacta tcagctgaag ctggtgtcct tcgggggctt catttccaaa aaggagaagc
     9541 tgcacagaca aaattgattc gggtagtcac tggagcagtt ttagatgtag tagtggatat
     9601 ccgcaaaggt agcccgactt atggtcaatg ggacggattt atcttatctg aacataatca
     9661 tcgacagttg cttgtaccta aaggatatgc ccatggattc gttactttga caccaaatgt
     9721 gaacttcctt tataagtgtg ataattacta taatgcagaa gcagatgggg gcatcgcatt
     9781 tgatgatcca gatttagcga ttgattggcc aattgatcca tcaagagcga ttatgtcgga
     9841 aaaagatcac cgtcatccga cattaaaaga atttgaagca gaaaatccat ttgtttacgg
     9901 agaaatctaa gaattaagga gaaattttct tatgaaaaac atcattgtta ccggaggtgc
     9961 cggattcatc ggctctaatt tcgttcatta cgtggtaaac aatcatccag aagtgcatgt
    10021 cactgttttg gataaactga cttatgcagg aaacaaagag aacttggctg gacttcctag
    10081 cgatcgcgta gaattggtcg taggagatgt tgcagatgca gaattagtgg accgtctagt
    10141 aaaagaagcg gacgcagttg ttcattacgc ggcagaatcc cataacgata attcattaaa
    10201 agatcctttc ccatttgtac aaacgaatat cattggtacg tatacacttt tagaagcttg
    10261 ccgcaagtat gatgtacgct atcatcacgt atctactgac gaggtttacg gcgatcttcc
    10321 attacgtgaa gacctgccag gacatgggga aggcgaagga gaaaaattca ctgcggaaac
    10381 accatataat ccttcaagtc catattcttc tacaaaagct ggttcagatc tgttagtaaa
    10441 agcatgggtg cgttcttttg gcttacgtgc aaccatttca aactgttcaa acaactatgg
    10501 tccttatcag catattgaaa aatttattcc tcgccaagta acgaatatct taagcggtat
    10561 tcgtccaaaa ttatatggcg aaggaaagaa tgttcgtgac tggatccata cgaatgatca
    10621 ttcttcagca gtgtggctga ttttgacgaa aggcagaatt ggcgaaacct atctgatcgg
    10681 tgcagacggt gaagaagata ataagaccgt gatggaattg atcttagaaa tgatgggtca
    10741 accaaaagat gcgtacgacc atgtaaacga ccgtgcagga cacgacttgc gttatgcaat
    10801 cgattcgaca aaattacggg aagagttagg atggaagcct gagtttacga acttccgtga
    10861 tgggttggct gacacgatca aatggtacga agaacatgaa gactggtgga aaaaagaaaa
    10921 agaggccgtt gaagcagcat atgccaaaaa tggacaataa tacagagaaa atgtcactgt
    10981 attaatggaa aaacacatgt gaggcaggcg ctcgcctgtc tcttttttaa aataaaaatc
    11041 aaggagcgga taatcatatg tttttattaa ctggaggaaa tgggcaacta ggtacagaat
    11101 tgcgccattt attagatgaa aaaaatctgc aatatgtttc aacagatgca aaagacttgg
    11161 atatcacaga tgccgagaaa acaatggctt acatcacaga attaaaacct gatgttattt
    11221 tccattgtgc agcttacaca gcagtagata aagcagaaga agaagcaaaa gaattagatg
    11281 agaagatcaa tgttgatggt acaagaaatg tagcacttgc agcaaaagct gtgaatgctc
    11341 aattcgtcta tatcagtaca gactatgttt tcgatggaaa aaacaaaaat gtagaatacg
    11401 aagtagacga ccaaacgaat ccactaaatg aatatggtcg tacgaaatta ttaggcgaaa
    11461 aagcagtaga agagatttta gaagactatt atatcatacg aacttcttgg gttttcggga
    11521 tctatggaca caatttcgtc ttcacgatgc aacgcctagc ggaaacccgc gacaaactga
    11581 ctgtagtaaa tgaccagttt gggcgaccaa cttggacacg tactttggca gaatttatgg
    11641 tatatgtcat cgaagaaaaa gcaccatttg gtatttatca tttgtcgaac gaaaatagct
    11701 gttcttggta tgaattcgca aaagaaatat tgaaagatac agatgtagaa gttgcacctg
    11761 ttacgtcaga agaatttccg caaaaagcaa cacgtccgca gtattcagtc atgagcctga
    11821 aaaagacaga agagttagga tttgtcatac caacttggca agaagcactt gcgcaaatgc
    11881 tggaagctgc caaaaaaatg aataagtaat ttccttttat caaatagaat ttggagcatg
    11941 atatggaaaa acaaacaaga agtgcacgac gaaaagaaaa gccaaaagcg aaccaggcag
    12001 attcgaattt ggtgcttgac ctgtttctaa aactccgcta tcttattggc gttttagtca
    12061 tcgtggtcat cgttactttt aatttaaacg gaagttcact tggtgtttgg gataaatatg
    12121 tgtcgcaaag agacgatggg aaaaaaactg atgtgatttt tggacagaat cgggaagtgc
    12181 ggtcagacga atggctggtg cagacacctt tttacctctc acaagctgaa gaggactttc
    12241 cgttggtgaa cgaggattat tcattaaacg gacaaaacat gatcattgcg tataattctc
    12301 ctgtaaagga tattacggtt atcggaaaac cattcaactg gggattcttt ttcctcggaa
    12361 gagatcgagg actttccttt tattgggcga tgaaattagt cgtcatggtc ttgcttggat
    12421 tcgaagtact gatgatatta acgaagagaa aaaaagctct atcgctaatc ggtgcatttg
    12481 cgctgacatt ttctccagca gtccagtggt ggttcatgca acatgtgggc gatttgattt
    12541 tctttacttt gggactgatg actgcttttt atcattattt ctacaatcat gataaaaaat
    12601 ggctacgaac gttgatgatg cttttggtgg ttattttcgg tattgggttt attttagtga
    12661 tttacccagc ccatcaagtg atgctggcgt acttgctgat tttttatttt gttggcctgc
    12721 ttatttacta tagcaagaaa gtttcatggg atctgttgga tgtagtgttg attggagggg
    12781 cagttttatt tattggcgga gtcatggttc atttctggct aacgtcaaaa gacgcattgt
    12841 tagcttcttt gaatacctta tatccaggaa aacgggtaag tactggagga aagtggacga
    12901 ttggcgaatt tttttctttc cttacaaatt ggaaaattcc ttttgaagat atcaactatt
    12961 cgaataactc tgaagtggcc ctgttctatc acttttttcc aactgtattc ctagcaagtc
    13021 catttgtgtt atttggcaaa aaagatagcg aacaaaagtt actgggacgt attttgatga
    13081 ttttttgtct gttttctatc ttttggatta ccgttgggtt gccaaaatgg ctagcagaaa
    13141 tcactctgct gtcttatgtt cctccattaa gagccatcct tacttttagt tttgcggctt
    13201 gtttattatc gatctggttt atcgcttata tttggagaga agatgttatt cctatttggt
    13261 ataaattcat tttgttggca gtaaatgcat ggtcttattt ctatgcgatt acgcattcga
    13321 aaatggataa ttatttttcg gattttgaaa ccatcgcagt tgctgtgttg ggaacagtga
    13381 ttttagcttt tgcattattt ggctggagac gcttgtttta cctcgctttt gccgccttag
    13441 ttatcgtatc tggctttttc gtcaatccag tcgtagaagg tacaggagcg atttttgaaa
    13501 aaacactggc aaaagaaatc caaaaaatcg atcaacaaga tcctggtaaa gtttggttgt
    13561 ctgaagatga attatataac ttcaccccaa cattgggagt gaaatccttc aatacagtac
    13621 gcttttatcc agatatagct gcatggaaga aaatcgatcc gaaagaagaa tacgagaagt
    13681 attataatcg gtatgctcat acaagagctt ttatcgctaa ggaagataca aagttcattt
    13741 tagatcgtcc agatatgttt tcggtcacgt tgaattttga agacgcagaa aaattaggga
    13801 tcgactatgt gatcagtaaa cgaccattaa ctgattacaa ccaattatat gaagcgcagt
    13861 tcacgcagct atatggaccg gataaagacg gttatatgat ttttaaagta gaatatccgg
    13921 attatccaga tgtaccacaa acacaaactc aggaaaatca gctagtcgta cagtaatagg
    13981 ctagctgaga ataatcctga aatgttagta gaaaggagag tggagataat tcaagcaatc
    14041 gtacaaaaat ttgtcaacaa aatgagtgtc ggtttcttgc ttttgttact gacgctagtc
    14101 ttttttgttt ggacagcagg gttaggtttt ccagcaactt tgtttatata taacaatagt
    14161 tcattactta tcgcttttag tgtggctatt ttgctcattt taaatgttta taaagcaaaa
    14221 ggcgtcgatt ttctttatct aggtgttgcg cttgcccttt tcattttctt ttcttacttt
    14281 cgggaattaa gaaatgagtc tttatttgga gacttactgt ttcctttgat tattttattt
    14341 tgtttagtaa ttaaatggat cgagtggaca aaatgggatc gcggtattta tctgattgtc
    14401 ttttcggtct tcctcggaat cacgtttatc gtgtatttac agagatccaa gtaccagaag
    14461 gacaaagcat ctgggctcca ggcaattcgc tttctgatat ttggatcaat acgaatacaa
    14521 tcggaagttc tttgatgact cttgctttat tgatcagtgg atttgccagt tcttttgaac
    14581 gatggtatgt acgaatcatc ggtgcagtag cagttgttgc agcttttctc gggatttggg
    14641 tctgccaatc tagaggtgca ttagtcgcgt tgattgtttt tgcgatattg gatcttttac
    14701 ctaaatcgtt gatgcgtgtc attcgtgcgc catttattgc ttacacggtt acgattcttt
    14761 tagctttgcc gatttcttat ctggcggctg tctctgaaaa agtcaatttg tttaccggtc
    14821 gagaagatat ttggcataaa ttctatcaga cgctaggaga aaaatctgaa caaattttac
    14881 taggaatgaa aacatttatc ttccaacgag gaaaccaatt tttaggaaac cacaatagtt
    14941 ataattctat tttgaatatc tatggattga taggatttgg gattgctgct ttgctgctta
    15001 tcctttttat tggtcgctta acgttgaaag cagatttatc caacgggcag atgactttta
    15061 tctgggcctt ttttgcggtg atgatgcagt catttatgga ggatacattg acttcataac
    15121 catgggttcc gattatttat atcctgttgg ctatggccgt tcatcgatat gatgaaccag
    15181 aagttgcgga ggaattctat gttatggaag aggcatatga cgatatgact tatgatgata
    15241 catcttatga ggaacaacca gatagcgctc attcttccag gatccaacgc tatcattgat
    15301 aggcacaaaa tacgagagag gctgtgacaa ccgtcgcagc cttttttggt ttattgcaat
    15361 tgtctagcat cttctgtaaa atagaaacgt tagagaaaat cttgtatcat agaaaattaa
    15421 gaaagaaata agaacgcagc tcggtaccaa aaatatggta aaatggcact tgactgtaat
    15481 tcactgaaaa tcgcttggag gaacacaaat gtttaaagat ttgtatttat ttatgaagga
    15541 catttatcag aacagaaaat tattgctaca gttttcgatc aatgacttca aatcaagata
    15601 tgcaggatcg tttttaggaa tcttatgggc gtttatcaat ccgctattta ctgtattgat
    15661 ttattggctg gtatttggtg ttggactgaa agcacaaatg atcgatgcaa aatacccatt
    15721 tatcgtatat ttagttaccg ggatgattcc ctggttcttc ttctcagatg catttgcatc
    15781 aactacggtt gtttttcggg aatatactta tttagtaaag aaagtcgtat tcaatattcg
    15841 tatcttgccc acgacgaaaa tcctatccaa tctgtacacc catttattct tcattctgat
    15901 tggcatagct gtcgcgctta taaatggtat atatccttca gcaatgtctt tacagctgat
    15961 ttattattta ttttgcatgt gtgctttctt gacaggattg acttggctga cggcatcgat
    16021 ccaaccattt ttacctgata tcatgcaatt aattacgatc gtgctgcagt tgatcatgtg
    16081 gacattaccg atattatgga gccctaatca gtttgattca ggtcttgtaa gcatattgaa
    16141 attaaatccg ctgtactatg ttgttcaagg ttatcgtgag tcatttttaa gtgaagcttg
    16201 gttctgggag catggaacat atactttgta tttctgggtt ttcacgttag taatgttcgt
    16261 aatcggctct gcagtgttcc gtagattgaa accacatttt tcagatgtgc tgtaaggaga
    16321 atagctatga cagaatatgc aattagacta aaagatatca caaaatctta taatatgtac
    16381 gcaaaacctt cggatcgatt tcgtgaagcc ctcaatcctt ttaagaaatc ctatcatgat
    16441 gtattttatg cgttgaaaaa cgtgaatgta gaaataaaaa aaggtgagat gatcggtttc
    16501 gtgggagaaa acggatcggg aaaatctaca atgttgaaaa tcattacggg agtactgaca
    16561 ccaacatccg gcacgatgga aatcgaagga aaaatctcag ctttgctaga actaggatca
    16621 ggattcaatc ctgagtattc tggctatgaa aatatctatt taaatggaat ggttctagga
    16681 ttttcaagag aagaagtcga tgaaatggtc gatgatatca ttgaatttgc tgacatcgga
    16741 gaccatattt atcaacctgt aaaaacttat tcaagcggga tgttcgttcg tctagctttt
    16801 gctgtagcaa tcaatgtgaa tcccgatatt ttgattgtgg atgaagcatt ggcagtaggc
    16861 gatcttgaat ttcaactaaa atgtatggaa aaatttacag aaatcaagaa ctcgggaaag
    16921 acgattttat tcgtttctca tgatatcagt tcgattcgtc gtttttgtga tcgttcctat
    16981 tggttgaaaa acggagaagt cgtcgaatat ggcgatacga tggaagtaac gacgaattat
    17041 gaaaactttt taaagaaaaa atcagttaaa acagtggatc ggaataaaaa ccaagtagaa
    17101 cggttcgccg ctccagatat cgtcgacgtg acgaaagcgg aattgttgga taaagacaaa
    17161 aatccggtgg atatgctgga acaaggagaa aaactatacg ttaaagtaac ttatgaagta
    17221 aaagatgata caatcaaaaa tccggtttta ggaattgcgc tacgaacagt cgacaatttt
    17281 tatgtatgcg gacttaatac tctactagat ggtatcaaga ttccttggaa aaaaggagag
    17341 aatatctttt atctggagta tgaaaagtta ggtttgttag ctggtgaata ttattttgac
    17401 gttgcggtct ttgaagaaaa tgcaacggtt cctttggtat ataagacaaa gtacatgaac
    17461 ttgtttgtca gcggttctta tatcggagaa ggcatcgtgg tcttagacca taaatgggaa
    17521 gaagggactc atagcaatga aatatgattt tgaaatggac ctagatgaac aaagcagtgt
    17581 gggaaaaatt gccgcacaga tcaaaccagg aagtaaagtt ttagagtttg gtcccggaaa
    17641 cggccgatta acgaaacatt taatcggagc aaaacaatgt gaagtgagca ttgttgagtt
    17701 agataaggaa ttgttcgatt ttgtcagcga atttgctcaa gatggatttt atggtgatat
    17761 cgaaagtttt gagtgggcaa actattatgc tggacagaca tttgattacg tcttgtttgc
    17821 ggatgtttta gaacatttgg tagatcctgg aaaaacattg aagaaagtca gagaattttt
    17881 gaatgaagaa ggagagatcc tgattacatt ccctaacttg gcgcataatt ctgtcatgat
    17941 cgatttgttc aataaccaat tgccgtgggc ttcttatggt ctcctagatg aaacccataa
    18001 ttctttttat actcatgatg gcttccaaaa agtttttgaa aaagcgggat tattcattaa
    18061 tattgaagat tatttgtact tagctgtagg tgatacagaa ttaaaatcaa cttatgaaga
    18121 attgccggaa gctgtacgct atgatttcaa aatgcgacca tttggtgaag tctaccaata
    18181 ctttttctca ttgatgaaac atccagtagc acaaagttcc attgcagagc cacaaaattc
    18241 taattatgta aaagtgttag aagtaaccca gcaaacgaaa caagatgaaa caatccaaca
    18301 aataccattc aataatttca caggggaaaa tgagacacta agtttccccg tatcagaaac
    18361 aacagaaaga atggtgtttc gcttcgcgca acaacctagc tttatcgaat tcagcgcaga
    18421 agctgccgga gaaaaactaa catttatcga ttcgaatgct gtagtcaaaa cagtaaatga
    18481 ttgttatttg tttgatggga aagaattacc agagttcgtt ctaacggata tttctgggaa
    18541 agaagtgact atccattgtc actatcgctt tatcggggaa ttgacaccaa caatgaaaga
    18601 attgttggaa acgattcgtc ccatggctga agtcacaaag cagctttctg agaaaaatga
    18661 cgaattagaa agagaaaatc atcatcttct tgaggaaaat acaagactag accatacgtt
    18721 aaaaacaacc acaaatcgct attgcacatt gttggaaagt gatgaatgga caataaaaca
    18781 tagactagga cgacgtaaga aagaaacttc gaaaaaaatc caagaaaaag aactttctat
    18841 atgtattgac gagaaaatct gggatgcaga aacaaaaata ttaaaaatca tcggatgggg
    18901 aatcgctaat tcggatcgcc agcccttgtc ctataagtta tcagctgacc aatcgccatt
    18961 tttcgaagca attcctgttt cacgagaaga agtcaatcaa gcagaacagc tcgcaaaagg
    19021 aacagaagcg ggatttgagt tacgaatcct ttgcgagcaa gaacgttcat tcttagtgga
    19081 agcagtagct caaaatggcc aatcatggat cattgaaatg taaataatga ttaacttata
    19141 aagataagga gtaaacgaat cgtgcaaaaa aaagaaattg ccgtatttat cgatcaaatc
    19201 actcgtgaac gggccactgg cgatttgctt attgtgggct gggcaattga tgaagtgacc
    19261 aaagaaatcc ctacgataaa ggtagaaaaa gaaaatgtga ttgctgaagc aacacatgtc
    19321 gtaagattgg atatcaatca tttatataat cttgatgtta agacccaaag cggttttaag
    19381 gtacgtttat cagggaaaat gagaggaaaa gccatcttag acttccaaac agcgagacat
    19441 caaaatggca tagctgtgaa attaaacggt aaataccctt atgatgacgg cattgaatct
    19501 tcatgggaaa gaaaaaaaag attactgaaa aaagggataa attatgcaag gactcatggc
    19561 gtaaaaaaag cgatccgtcg ggtcaaattg gaattgaagc caggatcgat cgactatgca
    19621 gagtggatca gtcgtcatga gaaaccagat ttgaaagagc aaaggaaaga agcacaagga
    19681 tttgcgtacc gtccattgat ttccatactt atgcctgtct ataacgttga aatcaaatgg
    19741 ctcgaaaaat gcattgattc ggtactggat caaacgtatg atcattggga actatgtatc
    19801 agtgatgatg cttctactga tccagctatc cgaaagtgtc tggaatccta tcaagcaaaa
    19861 gatgatagaa tcaaagtcgt tttccgaaaa gaaaatggac acatcagtct ggcaactaat
    19921 tctgcattgg aaatagcaga aggagaattt atagcactct tagataatga tgatgaatta
    19981 ccgccatttg cattatatga agtggcaaaa gtgctaaacg tacatccaga actggatgtg
    20041 atctacagtg acgaagataa aatcgatgca gatggcaatc gctttgatcc gcatttcaaa
    20101 gcagactggt cgcctgatac attgatggga aataattata tctctcactt aggcgtatat
    20161 cgaacaagca ttgttaaaga acttggcggt ttccgtaaag gctatgaagg ttctcaagat
    20221 tatgatttgg tccttcgtgt gacagaacaa atccctgcag atcatattta ccacattgac
    20281 cgagtcttgt atcattggcg gacgatccca ggatcaactg caagtaatgg cgaagccaaa
    20341 agttatatct atgattccgg agtgaaagca ttgacagatg ccctgtctag aagaaacatc
    20401 aaaggaagcg tacgtcctgg cagaatttct ggattttatg agattgctta tgacgtcttg
    20461 caagaggatt tggtcagtgt gatcattcca acgaagaatg gctatgaaga tctaaaaact
    20521 tgtgtggatt cgatcatcga aaaaacgtct tattcaaatt atgaaatcat tattgcggat
    20581 aacggaagta cagatccaaa aatgcaagaa ttatttgcag aatacaagca tcagctgaaa
    20641 gaccgcttta tcgtagaatt gattgacatt ccattcaatt attctcgaat taacaattta
    20701 gcagcagaaa aagcaaacgg caaatacttt ttattcttga ataacgatac agaagtgatt
    20761 gagccagatt ggatgacggt gatggtttct tatgcacagt ttgatcgaat cggctgtgta
    20821 ggagcaaaac tgttttatcc agatgataca acgcagcatg caggagtatt attaggaatc
    20881 ggtggtgttg cagggcatgc attgaataac tatgatcgaa cacattgtgg ttatttcggc
    20941 cgattggtca ttgacgtcaa ttacttagca gtcactgcag cttgtatgat ggtcaaggca
    21001 gctgacttca atgctgttaa cgggtttgat gaaacattag aagtagcatt caacgatgtt
    21061 gacttgtgct tgaaagttta tgaactgggt cgttacaatg tctatgcaca tcaagcagaa
    21121 ttgtaccatt tcgaatctaa atcaagaggt tatgaagata ctccagaaaa acaaagacgt
    21181 tttgctggtg aaatcaaaaa aatgcaagat aaatggccag catatattgc gcatgatcca
    21241 ttttacaatg ataatttaac aaaagaagga atcggcgact tttcgttgag accagattaa
    21301 actataataa aaagctgtta tgttgtgatt cgctcgcaca taacggcttt ttatagtttt
    21361 ttgtcaaaaa aaggcagaag gtgccgactc aaaaaaataa gtcgaggttg ggacagaagt
    21421 gtttaactcc gagaaataag aagaaattca cgaaaattgc ttttcaaatt tttgtgaatt
    21481 tcggcttatt taagaagaag ttgcttctgc tcccaccgtt tattcgtttt taaagaatga
    21541 gacaaaagtg tttcttactt ttgtcccacg ctcttattca tgctcagagc gccaatagat
    21601 acaaaatcat agccaaagtt tcacgaaccc tagctgtcaa agaatcgata ttttatttta
    21661 atataggcta ttttaaaata aatggtttaa ggtattcctc tacaaaagcc actctatcaa
    21721 ttatcatggg tttaaaataa gaagtgatgg agataaccag attgttctta gcgtcaatat
    21781 aaagaacatt tccactatta ccaattgctg aatatatttc gttctcagaa tctaataccc
    21841 accataaata gccatatctc atattttgta agtcttctaa agcactggtt ctaggtttga
    21901 acatctcgtt tatccacatg ggtggtacga tttgttttcc tttatacatc cctttattta
    21961 ggcataatac accaattttt gccagatcac ttgccgataa acacaaacca tatcctgccg
    22021 tcccgatatt tagtggatca caaaaccaga cattggtttt aggagactta tccattgtaa
    22081 actgcttatg ttcttcagct gtttcagcat aataattgac atggtttggt atccctatag
    22141 gatcaaatag atacttattg gcaaaatcaa cagttgttag cttacttgtc tgatacaaca
    22201 agccagttaa tatgtgtaaa cagacagttt gatagttgaa ttcgccggtt ataccttttc
    22261 ttcctcccaa taaatctagt gatgtttttg tccaatcttc acttgaacag acttttgtcc
    22321 atggatcgcc tttacatttg tagggtgctt tcattgttag caagtgcttg attgtaatag
    22381 cgtaaatagt tttctccccg cgtttcactt tatactctgg aaaataatct aatactttat
    22441 catcgatact tttgattaat ccttgctcta aagcaatgcc aatcagcaaa gatacaatac
    22501 ttttcgttgc tgacatgata tgacaagtat cgtctttttt ataaccattc cattcatctg
    22561 tataaacttc taccccatcc ttatatgcga caatttgaca tatatttggt tgtcgaaaac
    22621 caataaaatc atgcaactct tgtttattca taagatatta cctcactttc ttctataagc
    22681 ataatgtcat taaaaatcga tttcaatttt ttcgattctt cacgtaatac aggtattctt
    22741 atggactaga cagcgctttg ggaagatgga ttctctgaaa aatataaagg ttcactttat
    22801 gagtggataa aaaaagcagc aaatacttcg acttctttaa tttaccaaca ttagtgaaaa
    22861 tcgattcatc tggagatttg taatttagag tccttgtctt gattagaggt gtataaagct
    22921 ttttattaga catttttaaa ttccattaca atttgcttat aaactaggtt tttaaaggtg
    22981 actatggtaa gataatagag atattatttt gt
//
LOCUS       DAFBVQ010000045        22132 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.046, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000045 DAFBVQ010000000
VERSION     DAFBVQ010000045.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 22132)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 22132)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..22132
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.046"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..523
                     /locus_tag="LLC22_001897"
     CDS             <1..523
                     /locus_tag="LLC22_001897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBK5435173.1"
                     /translation="GGNFLTMLITPATVALAIPLYKNFRLLKENFYPVMAAILAGIVA
                     NCLVSVGFGYFFSLHKEMVISLLPKSVTTAISVDLSHTMGGVNAVTLAIVVSTGIFGS
                     LIATHIFRLFKIESPVARGVALGSTSHAIGTAKAIEIGEIEGIISGLAICVNGILTVL
                     LLPLFFQPFAGLF"
     gene            523..2109
                     /locus_tag="LLC22_001898"
     CDS             523..2109
                     /locus_tag="LLC22_001898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435174.1"
                     /translation="MRKPLFYATITKTFEHKKGGKDVYLSSEYLKQFDKDLYYKILLL
                     ESFEDQAWHTAAQLAQVVQLDARSVSKYLNELSKNYQQFSGKTHPLFTKNHRSGYNFY
                     DTLDSIEHERFLIYLVQSTLKFQLLHDIFFEEFHTMYQFAQKHYISESTAHRKINEWK
                     QQLQTYGIRLQRGTYIAQGEEEIIRLYLHMTFWQLFRGKIWPFETISQMDVKNMAEHI
                     MAFFNVRLNEIKKRRLEYMLGAFFLRKSQKHYVVLNEKKRRLISDNLLFQRFCQVMEP
                     VFPNYFQVEDELGALFLVLMTREEYYSDPKIRKKIFDFHQQAKTPPFTALSEAKAALS
                     LYQEEQGLPAENLTFEAENYLFSSHFFAYLFPNAKETIDGNSSDFINHLVIENKELKQ
                     WLVHFFESRHKHPNHLAFKNHAFLMGRYLTVFKTLGAFTPQLPKITILLMTDFPLFEE
                     QLLEEGLRTFFRNEYQLIFLPTDYRGREVDLLISTSKVHRKPWADLDYFIVTEELKLI
                     DYIQLSQKFEMIQKQKLLKQ"
     gene            2128..2349
                     /locus_tag="LLC22_001899"
     CDS             2128..2349
                     /locus_tag="LLC22_001899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016186310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2829 domain-containing protein"
                     /protein_id="HBK5435175.1"
                     /translation="MTFEEILPELKKGAKIIRKGWSGFELYVVLVSDDEFDGCPVTPY
                     LLIKTSDEGFSSFAPTVCDILADDWAIVE"
     gene            2346..3107
                     /locus_tag="LLC22_001900"
     CDS             2346..3107
                     /locus_tag="LLC22_001900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-ACP reductase"
                     /protein_id="HBK5435176.1"
                     /translation="MKNQYPDLAKQVVFITGAASGIGAAQARAFLEQDAFVFGLDQKF
                     GKMEEISLRFPETFAYALGDVRQMKELQQAVSKCQNHFGEVTILLNTAGILDAYKPLM
                     ETDESLWDLIYETNVKSMYQLTKIILPDMIRQKSGTIINMASIAGLIAGGGGIAYTSA
                     KHAIVGFTKQLALDYAGQGIRVKGIAPGAIQTPMNAADFEGKGEMAEWVANETPVKRW
                     AQPEEVAELTLFLASPQASYIQGTIIPIDGGWLLK"
     gene            3487..3996
                     /locus_tag="LLC22_001901"
     CDS             3487..3996
                     /locus_tag="LLC22_001901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="QueT transporter family protein"
                     /protein_id="HBK5435177.1"
                     /translation="MEKNNTRSAKRWTTTDVTRMALVTGLYVAVTLVLSVFSFGVIQI
                     RLSEMFNYLSLYNKRYIVAVTAGVALANIASPLGLIDVAVGSVSTLLVLLINYKITSR
                     IKNMKIKMAVTACVFAFSMFTVAGQLTILYQLPFFLNWWVIALGELASMIVGGIIIYW
                     IGKKVDLSK"
     gene            complement(4071..4610)
                     /locus_tag="LLC22_001902"
     CDS             complement(4071..4610)
                     /locus_tag="LLC22_001902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="biotin transporter BioY"
                     /protein_id="HBK5435178.1"
                     /translation="MNRTLKELILAAEFAAIISVLSQMTIPFGLVPLTGQTFAIGLTA
                     TFLGRKLGLISVGVYLLLGLIGLPVFSGMTGGIAVLFGPTGGYLIGFLLQTWITGWMI
                     ERTDAHYLYAIFANLMGSLAALICGTIWLKISGDLTFTTAFASGLLPFLLPEAIKATG
                     AAYIGILMKKRLNRFLHTN"
     gene            complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="LLC22_001903"
     CDS             complement(4750..5361)
                     /gene="rpsD"
                     /locus_tag="LLC22_001903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734406.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S4"
                     /protein_id="HBK5435179.1"
                     /translation="MSRYTGPSWKISRRLGISLSGTGKELARRPYAPGQHGPNSRGKQ
                     SEYGMQLTEKQKLRHMYGMNERQFRNLFVKASKIKEGKHGVNFMILLEQRLDNVVYRL
                     GLATTRRQARQLVNHGHILVDGKRVDIPSYHVEVGQVISVREKSQNIVTVKEAVEATV
                     GRPAFVSFDAEKLEGSLTRLPERDELYPEIDEALVVEYYNQSL"
     gene            5623..6474
                     /locus_tag="LLC22_001904"
     CDS             5623..6474
                     /locus_tag="LLC22_001904"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="formate/nitrite transporter family protein"
                     /protein_id="HBK5435180.1"
                     /translation="MRGYVQMEKSEGSLRRKSMNPVSPLFEKIDASIEKKANLFENSF
                     SRYAVRAVLACLFLTLGTAVAFAIAMKGEDIAHGLGKILYAFMFSWGLVMILYMNAEL
                     GTSNMLYMTVGVFRQRLALSKAAKILFACIFFNMIGGILCGFLISMTTPFQDLTLDNF
                     MLESIAVKLAKPSATILVEGMFANIVVNTAVLISMRMKEDVGKVITVVFIIFIFAFLG
                     YEHVIANFPAFTLTYFASHGQMDGMTVSNVLHNLFFALAGNYIGGGLVMGLGYAWLNQ
                     SKSSYVD"
     gene            6502..7137
                     /locus_tag="LLC22_001905"
     CDS             6502..7137
                     /locus_tag="LLC22_001905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294262.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA alkylation repair protein"
                     /protein_id="HBK5435181.1"
                     /translation="MEVLVFPKNEEKALQMEKYMKNLFSFAGVPKPERALLQQPLLDE
                     SKNLSISEVLAFVHYYYEQIEREYQYVAIDLVQKNIKRLTFEDLVVLLPLVQKKEWWD
                     SIDSWRKVYSTWCKAYPEQREEVFQLFEKKEDFWLRRIAITLQLGYKQQTDTGLLIRA
                     IDEDRQTKEFFIQKAIGWALRDYSKTDADWVKRQLTTDLSKLAVREASKYL"
     gene            7157..7930
                     /locus_tag="LLC22_001906"
     CDS             7157..7930
                     /locus_tag="LLC22_001906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5435182.1"
                     /translation="MRRKLFAFDIDGTLLDSNKQALDSTREALEKLRKAGHLVTIATG
                     RSRFHAQEIIRDLDFTNYILCNGAAGFLDHEQVYKNLLDRDQLDAFVQEAHHEQIDTA
                     FVSLDNIKRSSSNDVTVMEEAMHSFGAVLPELDQFFAEEQEIYQALAFFDQTYDGKFS
                     SYDKIRFVRWHENSVDVVPKNGSKAATILHLAEQVGIPHEDIISFGDGQNDREMLRMS
                     GIGIAMGNAVPEVQAEAKMVTDTNDQDGIWKALKELSVI"
     gene            8338..9135
                     /locus_tag="LLC22_001907"
     CDS             8338..9135
                     /locus_tag="LLC22_001907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR00282 family metallophosphoesterase"
                     /protein_id="HBK5435183.1"
                     /translation="MRVLFIGDVVGSMGREMITEYLPRLKKKYRPQVTIVNGENAASG
                     RGITEKIYKKFLQDGVDVVTMGNHTWDNRGIFEFVNEAKKMVRPANFPEGTPGQGMVF
                     VKVNQVELAVINMQARSFMVDLDDPFRKMNELVEEARKRTPIIFVDFHGETTSEKQAM
                     GWFLDGKVSAVVGTHTHVQTNDARILPRGTAYLTDVGMTGPYDGILGMRREPVIEKFL
                     TALPKRFEVVEQGRSILSGCILELDDTTGHAKEIQLIQINDDRPFME"
     gene            9113..9526
                     /locus_tag="LLC22_001908"
     CDS             9113..9526
                     /locus_tag="LLC22_001908"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlbF family regulator"
                     /protein_id="HBK5435184.1"
                     /translation="MIDRSWSRKRGSFLQQEPEIQKEVRKLTKLLRENETIIRYKELE
                     EKIQQNQYLAELREKIKQAQKDAVHFAHYDKPAAEKEAIKQADQFMQEFDQHPLVVAY
                     RKQLLEADDLLHHLTTMIQEEINGQIEEEKHASKN"
     gene            9510..12155
                     /gene="mutS"
                     /locus_tag="LLC22_001909"
     CDS             9510..12155
                     /gene="mutS"
                     /locus_tag="LLC22_001909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBK5435185.1"
                     /translation="MPQKTKNTPMMEQYLSIKAQYQDAFLFYRLGDFYELFYEDAIKA
                     SQLLELTLTSRNRNAEEPIPMCGVPHHAAQGYIDALIEKGYKVAICEQVEDPKTTKGM
                     VKREVIQLVTPGTVMDSKGLSAKDNNFLTAVVSQGNEFGFAYADLSTGELKTARLHDE
                     EAVLNEASALQTKELVLGSEITDTLREQLSGRLGLVFSQQNEMEENAEFSFLTSELVD
                     PLEKEATGKLLTYLSVTQKRSLAHIQKAVEYQPDHFLKMDYYSKFNLELSQSIRTGKK
                     HGTLLWLLDETKTAMGGRLLKQWLDRPLIQAKQIKARQEMVASLLDSYFERIDLQSAL
                     TKVYDLERLAGRVAFGNVNGRDLIQLKTSLEQVPMIRGLIEGIDQGQWQSLLSEMQPM
                     DHLVQLIDQAIQDDPPLQITEGNIIKDGFNEQLDMYRSAMRNGKKWLAELEAKERQET
                     GIKNLKIGFNRVFGYYIEITKANLGNAELEKYERKQTLANAERFITPELKELETQILE
                     AEEKSVDLEYQLFLAVREEVKKAIQPLQVLAKAISAVDVLQSFATISERYQYVRPELV
                     SDKHQLLIKDGRHPVVEKVLGHQEYIPNSVEMAEDEMILLITGPNMSGKSTYMRQLAL
                     TVLMAQMGCFVPAKQAVLPIFDRIFTRIGASDDLIAGQSTFMVEMMEANQALRYATPN
                     SLILFDELGRGTATYDGMALAQAIIEYIHRHVQAKTLFSTHYHELTVLEKELPQLKNV
                     HVGAVEKDGEVVFLHKMMDGPADKSYGIHVAKIAGLPSNLLERAADILHTLENGDNGH
                     HTVPAEVEEKTKTAKQEQIKPPAEKVNQDHIQDRVKEENQQLSLFSELSENETEVIES
                     LKQINLLEMTPMDALNTLYELQKQL"
     gene            12173..14281
                     /gene="mutL"
                     /locus_tag="LLC22_001910"
     CDS             12173..14281
                     /gene="mutL"
                     /locus_tag="LLC22_001910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair endonuclease MutL"
                     /protein_id="HBK5435186.1"
                     /translation="MAKIQELSERLANQIAAGEVVERPASVVKELVENAIDAGSTQID
                     ILVEEAGLRTIQVIDNGEGILADDVENAFKRHATSKIHNRDDLFRIRTLGFRGEALPS
                     IASVSEMTLETANQEEKQGTYLSLKGGEVIEHRPAPLRQGTKITVSNLFFNTPARLKY
                     VKTLHTELANIGDIVNRLALSHPSIAFRLVHDGNKMLATAGNGDLKQTIAGIYGLSTA
                     KKMLKIEGKDLDFELFGYVSLPEVTRASRNYLSTIINGRFIKNFSLNKAIVAGYGSKL
                     MVGRFPIAVLEIKMDPLLVDVNVHPTKQEVRLSKEKELTELISNAIQKALSQENLIPS
                     AADNLRFKKKVPDQPKTEQIEIDLSYAFEEEKPKKPSSLNFDRETGTFFVEELKNTFV
                     DRIVDKSVENVENYSGFSEENTTYPEKTAKTVDKFGENVDNFVEKTVEKSEKKEFPIV
                     DNMEKTNEEQADKSVEEDEKIYEEELTLHPEFDFTQGNDKTLEQAIKKLETEKPVQRF
                     PQLEYFGQMHGTYLFAQSSDGLYIIDQHAAQERIKYEYFREKIGEVSDDLQELLVPFV
                     LDYPNSDALKLKEQKHLLEDAGIYLEEFGQNSFIVRAHPTWYPNGEEESIIREMIDML
                     LTTGSVSVKKFREATAIMMSCKRSIKANHYLNEAQARVLLKDLARCENPFNCPHGRPV
                     LIHFTNSDMERMFKRIQDPH"
     gene            14303..14863
                     /gene="maf"
                     /locus_tag="LLC22_001911"
     CDS             14303..14863
                     /gene="maf"
                     /locus_tag="LLC22_001911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348596.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="septum formation inhibitor Maf"
                     /protein_id="HBK5435187.1"
                     /translation="MKIVLASQSPRRKELLAHIVSEFEIEPADIDETPFPDEQPVDYV
                     RRMAEEKARTVWEQDEKEDHLVIASDTTVVLNQEIMGKPEDLAEAEFMLKKLSGETHT
                     VYTAVVLKTKEREERILAEAHVTFYPLTDEEIKRYLETGDYADKAGAYGIQNAASVFV
                     KEISGDYYSIVGFPIGAVNQALKTFI"
     gene            complement(14948..16936)
                     /gene="treP"
                     /locus_tag="LLC22_001912"
     CDS             complement(14948..16936)
                     /gene="treP"
                     /locus_tag="LLC22_001912"
                     /EC_number="2.7.1.201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324281.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system trehalose-specific EIIBC component"
                     /protein_id="HBK5435188.1"
                     /translation="MAKYQADAEKLLHDIGGKENIAAVSHCATRMRFVLNDPGKADEK
                     AIEDIPSVKGMFTNAGQFQVIIGNDVSTFYNDFVAVSGVEGVSKEQGKAAAKQNLHPV
                     QRAIAVLAEIFTPLIPAIIVGGLILGFRNVLEGIQFESLGGTIVEHSKFWNGVNAFLW
                     LPGEAIFHFLPVGITWSIAKKMGTTQILGIVLGITLVSPQLLNAYSVASTAAADIPFW
                     DFGFAQVQMIGYQAQVIPAMLAGFMLAYLEIFFRKYIPQSISMIFVPLFSLLPTVLAA
                     HVILGPIGWTVGSWISNIVNTGLTSSISWLFSAVFGFLYAPLVITGLHHMTNAIDMQL
                     IADFGSTNLWPMIALSNIAQGSAVLAIIFLHRGNKKEEQISIPAMISCYLGVTEPAMF
                     GINLKYVYPFVAAMVGSGLAGMFANLMGVRANAIGVGGLPGILAIQAETWVPFIIAMI
                     IAVIIPFGLTIIFRRQGILNKIDPAVPENAADVQLQTANGATATPQSFEPVSATGTAV
                     ATKETLFAVAAGTIKEITEVNDPVFSQKMMGDGYAVEPSNGKVYAPVNGKVTSVFETK
                     HAIGILSNEGLEVLVHMGLDTVELKGVPFNVFVKEGYLVTPETLIAEMDLPEIEQAGK
                     KTDIIVALTNNEKVAGLSLDQSGLVRPGEAVGKAEVKS"
     gene            17159..17872
                     /gene="treR"
                     /locus_tag="LLC22_001913"
     CDS             17159..17872
                     /gene="treR"
                     /locus_tag="LLC22_001913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trehalose operon repressor"
                     /protein_id="HBK5435189.1"
                     /translation="MNKFNEIFLDLEQKILAKEYPPHSLLPSENQLIKIYGVSRETIR
                     KALNLLTTEGYIQKKQGKGSIVLDRNRFDFPISGLTSYKELQETQRIPSETIIHTLEE
                     TEVTKALNEITGWEIGAPVWHLIRERKINGEVVILDTDYLLKEIVPILTPAQAQGSIY
                     EYFENELSLTIAYAQKEITVEEVTEIMKTAMDLHDDTYAVVVRSLVHLEDTRCFEYSE
                     SVHRLDKFRFVEFARRRKV"
     gene            17949..18395
                     /gene="msrB"
                     /locus_tag="LLC22_001914"
     CDS             17949..18395
                     /gene="msrB"
                     /locus_tag="LLC22_001914"
                     /EC_number="1.8.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (R)-S-oxide reductase MsrB"
                     /protein_id="HBK5435190.1"
                     /translation="MDKPIRPEKEELKEKLSPMAYAVTQENATERPFSGKYDDFYEKG
                     IYVDIVSGEPLFSSAEKYDAGCGWPSFSKPITKRQVREKADFSHGMHRIEVRSKEADS
                     HLGHVFTDGPVDQGGLRYCINSASLKFIPYEKMDELGYGEFKSLVE"
     gene            18565..19167
                     /gene="ruvA"
                     /locus_tag="LLC22_001915"
     CDS             18565..19167
                     /gene="ruvA"
                     /locus_tag="LLC22_001915"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294251.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration protein RuvA"
                     /protein_id="HBK5435191.1"
                     /translation="MYEYLTGVVTFINPYYIVVETNGIGYQIALGNPYRYSSKLNQKI
                     KIYVHQVIREDAHLLYGFDSLEEKQLFLRLVSVSGIGPKSALAIMASEDHSGLIQAVE
                     SSDVTYLTKFPGVGKKTAQQMILDLKGKFGELSIDTPFSLFDEANTKDATALSEAMEA
                     LSALGYSDREIKRVEKQLKEVDNQTTDEYLRQALKLMMKK"
     gene            19180..20181
                     /gene="ruvB"
                     /locus_tag="LLC22_001916"
     CDS             19180..20181
                     /gene="ruvB"
                     /locus_tag="LLC22_001916"
                     /EC_number="3.6.4.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Holliday junction branch migration DNA helicase
                     RuvB"
                     /protein_id="HBK5435192.1"
                     /translation="MTDEYLLSPESGENELSLEKSLRPQLLSQYIGQRKVKQELQIYI
                     EAARNREEPLDHVLLYGPPGLGKTTMAMVIANEMTVNIRTTSGPAIERPGDLVAILNE
                     LEAGDVLFIDEIHRLPRVVEEMLYSAMEDFYVDIMVGQGPTAHPVHFPLPPFTLIGAT
                     TRAGMLSAPLRDRFGIISHMEYYDEQDLQEIVLRSSDIFQTEIIEEGALEIARRSRGT
                     PRIANRLLKRVRDFAQVQGDGKIDRPIADQALTLLQVDQAGLDYVDQKLLRTMIELYG
                     GGPVGLSTLSVNIGEERETVEDMYEPYLIQKGFLKRTPRGRIATAYAYEHFGYDYHI"
     gene            20210..20788
                     /locus_tag="LLC22_001917"
     CDS             20210..20788
                     /locus_tag="LLC22_001917"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5435193.1"
                     /translation="MSDTTRTKQLIKNVLIDLCQTQSFRKISVQKIANEAKINRQTFY
                     YHFTDKYDLLRWVYCEDALHYLDPQCLSLDNWEEQALKMLKAIAEKKEFYANTVLSDP
                     EILQKEFSQLIQKSFIKIFEQMDEERQLSARDKLFYARFFSYGCSGVLVNWITNEYEE
                     TPMEIAMQLFRLAKDTELYSYRLYAKEELEEQ"
     gene            20840..21322
                     /locus_tag="LLC22_001918"
     CDS             20840..21322
                     /locus_tag="LLC22_001918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="low molecular weight phosphotyrosine protein
                     phosphatase"
                     /protein_id="HBK5435194.1"
                     /translation="MTKILFVCLGNICRSPMAEGLLRKRIALEGREAEFFVDSAATST
                     YEVGKTPHPGTKKILNQEKVDMTNMVARQITPHDFETFDWIIGMDQENVEELKRRAPR
                     SAQGKIHLFLSSIPGKEKENVPDPYYTNNFDETYHLITEGLNHWWNIWIDENKITNNL
                     "
     gene            21439..21813
                     /locus_tag="LLC22_001919"
     CDS             21439..21813
                     /locus_tag="LLC22_001919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435195.1"
                     /translation="MNEETVSPMKKLTKLVTHTSYQLFDSFVNDTEEHAKNVRLQGKF
                     ILELQKAATEHSLVILQVRANRLSSKYETISGWVATKTVEKDRVMIRLQNEEQQIRMV
                     PVEQIEKITILSPAGEQERLSK"
BASE COUNT         7237 a         3991 c         4790 g         6114 t
ORIGIN      
        1 cgggggcaat tttttgacta tgctgattac tcctgcgaca gtggcacttg ccatccctct
       61 ttataaaaac ttccgtttac tgaaagagaa tttttatcct gtaatggctg cgattttagc
      121 aggaatagtc gcaaattgct tggttagtgt agggttcggt tacttcttct ctcttcataa
      181 agagatggtg atctcattac tacctaaatc tgtaacgacg gctatttctg tcgatttatc
      241 tcatacgatg ggcggggtga atgccgtgac acttgctatt gttgtctcta caggtatttt
      301 tggttcgctg atcgccactc atattttccg cctattcaag atcgaaagtc cagttgctcg
      361 cggtgtggcg ttaggaagta cttctcatgc tattggtaca gcaaaagcaa tcgagattgg
      421 tgaaatagaa ggaatcattt ccggacttgc gatatgcgtc aacggaatat tgaccgtttt
      481 attgctaccg ttattctttc agccttttgc tggcttgttt tgatgcgaaa accactattt
      541 tatgctacaa taaccaaaac gttcgagcat aaaaaaggag ggaaagacgt gtatttgtct
      601 tccgagtatc ttaaacaatt tgataaagat ctatattata agattctcct cctagaaagt
      661 tttgaggatc aagcttggca taccgctgca caattagcgc aagttgttca gctggatgcc
      721 cgcagcgtgt cgaaatacct gaacgagctg tctaaaaact atcagcagtt tagcggtaag
      781 acacaccctt tgtttacaaa aaatcaccgt tctggttata acttttatga tacgctcgat
      841 tcaattgaac atgagcgttt tttgatctat ctcgtgcaaa gtacgctgaa attccagttg
      901 ctgcacgaca ttttttttga agaattccat acaatgtacc aatttgcgca aaagcattac
      961 attagtgaat ctactgctca tcgaaaaatc aatgaatgga aacagcaact gcaaacttac
     1021 ggaattcggc tgcaacgagg tacatatatc gctcaaggcg aagaagaaat cattcgactt
     1081 tacttgcata tgacattctg gcagttgttt cgagggaaaa tctggccatt tgaaacgatt
     1141 tctcaaatgg acgtaaagaa tatggcagaa catatcatgg ctttttttaa tgttcgtctg
     1201 aacgagatca aaaaaagacg attggaatat atgctaggtg cctttttttt aagaaaatca
     1261 cagaagcatt atgttgtatt gaatgagaaa aaaagacggc tgatttctga caatctgttg
     1321 ttccagcgat tttgccaggt catggagccg gtatttccta attattttca agtagaagac
     1381 gagttaggcg cattatttct tgtactgatg actcgtgaag aatattatag tgatcctaag
     1441 atacggaaga aaatttttga ttttcatcaa caagcaaaaa caccgccctt tacagccctt
     1501 tcagaagcaa aagccgctct ttctctttat caggaagagc aggggctgcc agcagaaaat
     1561 ctaaccttcg aggcagaaaa ctatttattc agcagtcatt ttttcgccta tctttttcct
     1621 aatgcgaaag aaacgattga tggcaatagt agtgatttta ttaatcattt agttattgaa
     1681 aacaaggaat tgaaacaatg gctcgtacat ttttttgaaa gtagacacaa acatcccaat
     1741 catctggcat ttaaaaatca tgcgtttttg atggggcggt atctgactgt gtttaaaaca
     1801 ttaggagcct ttactccaca gcttccaaag atcacgatcc ttttaatgac agatttccca
     1861 ttatttgaag agcaactgtt agaggaggga ttacggacat ttttccgtaa tgagtatcag
     1921 ctgatttttc tgccaacaga ttatcggggg agagaagttg atcttctgat ttcgacaagt
     1981 aaagtccacc gcaaaccatg ggcggatctt gactatttta ttgtgactga agaactaaaa
     2041 ttaattgatt acatccaact atctcaaaaa tttgaaatga ttcaaaaaca aaaactatta
     2101 aaacaataac aaagaaggag aaaaaagatg acatttgaag aaattttacc agaattgaaa
     2161 aaaggtgcaa agattattcg taaaggatgg agtggatttg aactttatgt tgttctcgta
     2221 tccgatgatg aatttgatgg ctgtccggtg acgccgtact tattgatcaa aacaagtgac
     2281 gaaggttttt ccagcttcgc tcctacagtt tgtgatattt tagcagatga ttgggcgatc
     2341 gtagaatgaa aaaccagtat ccagatctag ctaaacaggt tgtatttatc acaggagctg
     2401 cttctggaat tggtgctgcg caagcccgag cgtttcttga acaagatgct tttgtatttg
     2461 gattagatca aaagttcggt aaaatggaag aaatttcttt gcgatttcct gaaacttttg
     2521 cctacgcact aggtgatgtt cgacaaatga aagaactcca acaagcggta tcgaaatgcc
     2581 aaaatcattt tggtgaagtt acgattttac tgaatacagc ggggatattg gatgcctaca
     2641 aacccttgat ggaaactgac gaatcgctgt gggatctgat ttatgagacg aatgtgaaaa
     2701 gcatgtatca gctgacaaaa atcatccttc ctgatatgat ccgccaaaaa agcggaacga
     2761 tcatcaatat ggcttcgatt gctggcttga ttgctggtgg aggtgggatc gcttatacaa
     2821 gcgcgaaaca tgcgattgtc ggatttacca aacaactcgc tctggattac gcaggacagg
     2881 gtatccgagt aaaaggaatt gctccaggag ccatccaaac accaatgaat gcggctgatt
     2941 ttgaagggaa aggtgagatg gcagagtggg tggcaaatga aacaccagtc aagcgatggg
     3001 cacagccgga agaagtagct gagctgacgt tatttcttgc ctctcctcaa gcaagctaca
     3061 tacaaggaac gatcatccca atcgacggcg gatggttgtt aaaataacct tgtgtttttt
     3121 tcaagcttct gtatgataaa actaaagaga gaaacaacgg ttgatgataa aaaaagtcga
     3181 tgactgttcc cgacattcga tgccgaacag ccagttcaaa aaattctttt taataatcgt
     3241 taatattcga aactaagcgg cttttcacga cctcttgata taaacgatat tcaaaagctt
     3301 gcaactgcgg taacaagtcc agccaaatga aaaatataag gagctatttt tatttgacca
     3361 ttcttattac ttgttgcagg gcagcttttt cactaccttc tgcgacactt cagttggaat
     3421 tttcttccca tcctttggtc gcggtcatta ccaagataaa attatcttgc aaaggagaaa
     3481 tagaacatgg aaaaaaataa tacccgttca gccaaacgct ggacaacgac agatgtgact
     3541 cggatggcgc tagtcactgg tttatatgtg gcagtgacgc tggttttgtc tgtctttagc
     3601 tttggagtga ttcagattcg tctctcggag atgttcaact atctgtcctt gtataacaaa
     3661 agatacatcg tcgcggtaac agcgggagta gctttggcta atattgcttc tcctcttgga
     3721 ctgatagatg ttgcagtagg aagcgtcagc acgctgcttg tattgcttat caactataaa
     3781 atcactagtc gcatcaaaaa catgaaaatc aaaatggccg tgacagcatg cgtatttgct
     3841 ttttccatgt ttacagtagc tggtcagcta acgattttat atcaactacc ttttttcttg
     3901 aattggtggg tgattgcttt aggagaattg gcatcaatga ttgtcggtgg gataattatt
     3961 tattggatcg gtaaaaaagt ggatttgtca aaataaagat ctgtttaatt taaaataggg
     4021 cagcatggaa gagactgaat gttgagtctt cttccatgct gcttttttga ttaatttgta
     4081 tgaagaaatc gatttagccg ttttttcatc aagataccga tataagctgc tccagttgcc
     4141 ttgattgctt ccggcagtaa aaacggcagt agtccactgg caaatgcagt tgtaaaagta
     4201 agatcaccac ttattttcag ccagatcgtt ccgcagatca atgcagcaag agagcccatt
     4261 agattggcaa agattgcata taagtaatga gcatccgttc tttcgatcat ccaaccagtt
     4321 atccacgttt gtaagagaaa tccaatcaaa tatccgccag ttggcccaaa taaaacagct
     4381 atacctccag tcatccctga aaatacagga agaccaatca agccaagtaa aagataaact
     4441 ccaacagata tcaatcctag ttttcttccg agaaaagttg ctgttaatcc aatagcaaat
     4501 gtttgccctg tcaaaggaac caaaccaaaa ggaatggtca tctgagaaag gacagaaata
     4561 atcgcggcaa attccgcagc aagtatcaat tctttcaatg ttcggttcat aacgccctct
     4621 tttcgttaac ttaatatttt tatttggtta acgaaattgt aaaacaaagt gattactttg
     4681 taaatagaaa atataaaaaa agaccagcta tccaatagat agcggtcttt ttcaagaaag
     4741 cttttgaaat tataagcttt ggttgtagta ttcaacgaca agagcttcgt cgatttctgg
     4801 atatagttcg tcacgttctg gtaaacgagt caatgaacct tccaattttt cagcgtcaaa
     4861 gcttacgaat gctgggcgtc caacagttgc ttctacagct tcttttactg ttacgatgtt
     4921 ttgtgatttt tcacgaactg agatcacttg acccacttct acgtggtatg aagggatatc
     4981 aacgcgtttg ccatcaacta aaatgtgacc atggttaact aattgacgtg cttgacgacg
     5041 agtcgttgca agtcctaaac ggtaaacaac attgtctaaa cgttgttcta gtaagatcat
     5101 gaagttaaca ccatgtttac cttctttgat tttgctagct tttacgaaca agttacggaa
     5161 ttgacgttcg ttcattccgt acatgtgacg aagtttttgt ttttcagtta attgcatgcc
     5221 gtattctgat tgtttgccac ggctattagg tccatgttga cctggtgcgt aagggcgacg
     5281 tgctaattct tttcctgtgc ctgacaatga gatgcctaag cgacgagaaa ttttccatga
     5341 tggtcctgta taacgagaca ttaaaatttc ctccaatgaa tataagtttt tggagtaaaa
     5401 taatccgttg aaaaattcat aatcatatag tttgttcttc aatcttcacc tttgcagccg
     5461 cggttacaca atcgaacccg agacggggca acaaactagg gatgagttat tatttttctg
     5521 ctgcattatt ttacacaaat tacagtatat gatagatcat ccacgaatgt caagataatt
     5581 agtacataaa aacgctttac aaacctaggc tgtctttata aaatgagagg gtatgtgcaa
     5641 atggaaaaaa gcgaaggaag tttaaggaga aaatcaatga atccggtatc accattattt
     5701 gagaaaatcg atgcttcaat tgaaaagaag gcgaatcttt ttgaaaacag cttttcacgt
     5761 tacgctgttc gagcggttct cgcctgtttg tttttgactt taggaacggc tgtggcattt
     5821 gcgatcgcga tgaaggggga agatatcgcg catggtctag gaaagatttt atacgcattt
     5881 atgttcagct ggggtctggt catgattcta tacatgaacg ccgaattagg aacatcgaat
     5941 atgctttata tgaccgtggg tgtttttcgg cagagacttg ctttaagtaa ggcagccaag
     6001 attctatttg cctgtatttt tttcaatatg attggcggta tattatgtgg atttctaatt
     6061 tctatgacta cgccatttca agatttaacg ttggacaact ttatgttaga atcaatagca
     6121 gtaaaactag caaaaccttc agcaacgatt ttggtggaag ggatgtttgc gaatatcgtt
     6181 gtcaataccg ctgtactgat cagcatgcgg atgaaagagg atgtcggaaa agtgatcaca
     6241 gtcgtattca tcattttcat ttttgctttt ttaggatatg aacacgtgat agcgaatttt
     6301 cctgccttta cgcttactta ctttgcttct cacggacaga tggatggaat gacagtcagc
     6361 aatgtgttac ataatttgtt ttttgctttg gcaggaaatt atattggtgg cggtttagta
     6421 atgggactgg gatatgcttg gctgaatcag tcaaaatcat cctatgtgga ctaaaaagtc
     6481 gttcattaaa ggggaagtgc catggaagtt ttagtttttc caaaaaatga ggaaaaagcg
     6541 ttacaaatgg aaaagtacat gaaaaatctt ttttcctttg ctggagtacc taagccggaa
     6601 cgcgctcttt tacaacaacc gttactggat gagagcaaaa atttatctat ttctgaagtt
     6661 ttagcttttg ttcattatta ttatgaacaa atcgaaagag agtatcagta tgtagcgatc
     6721 gatttagtcc agaaaaacat caaacggctt acatttgaag acttagtcgt attgttgcca
     6781 ctagttcaga aaaaagaatg gtgggacagc atcgactctt ggagaaaagt atacagcaca
     6841 tggtgtaaag cctacccaga gcagcgtgaa gaagtctttc aattgtttga aaaaaaggaa
     6901 gatttttggc tacgtcgaat agcaatcacg ttgcaattag gttataaaca gcaaacagac
     6961 acaggactat tgatccgagc aatagacgaa gatcgtcaaa caaaggaatt ctttatccaa
     7021 aaagcaattg gttgggcatt acgcgattat agtaagaccg atgccgattg ggtaaaaaga
     7081 cagctgacaa cagatttgag taagttagct gttcgagagg caagtaagta tttataagaa
     7141 agcgagacga caagagatga gacgcaaatt atttgctttt gatattgatg gaacgttgtt
     7201 agattcaaac aaacaagctt tagatagcac aagagaagca ttggaaaaat tacgcaaagc
     7261 cggtcatctg gtcacgattg ctacagggcg gagccgattt catgcgcaag agatcattcg
     7321 cgatcttgat tttacgaact acattttatg taatggagcg gccggttttt tagaccatga
     7381 acaagtatat aagaatttac tagatcgcga ccagttggat gcgttcgttc aagaagcgca
     7441 tcatgagcag atcgatacag cttttgtcag cttagacaat atcaagcgtt cttcttccaa
     7501 tgatgtaacg gtgatggaag aagcgatgca ttctttcggt gctgtcttgc ctgaattaga
     7561 tcagtttttt gcagaggaac aagaaatata ccaagcgtta gcatttttcg atcaaacata
     7621 tgatgggaag ttctcttcat atgataaaat tcgatttgtc cgctggcatg agaacagtgt
     7681 agatgtcgta cctaaaaatg gttctaaagc agcgacaatt ctgcacttag cagaacaagt
     7741 aggcatccct catgaagaca tcatcagctt tggcgatgga caaaacgacc gtgaaatgtt
     7801 gcgcatgtca ggaattggga tagctatggg gaatgctgtg ccagaagtac aagcagaagc
     7861 taagatggtc actgatacaa acgatcagga tggaatttgg aaggcattga aagagttaag
     7921 cgtgatttaa aagaggttgt gaaaaagctg ttctgcatca agtaataagc ccagccaaac
     7981 aaaaatagct cctcctattt ttcgtttttc tgggcttatt accgcagatg caagctttcg
     8041 aacaccgttt aaggaagagg tcgtgacaga agtggtcagt ttcaagaaat aagaagggat
     8101 ttacgaaaat tgcttctcaa atttttgtaa aattacggct tatttctgaa gaagtagatg
     8161 aaacaacgtt tattcgggaa atgggactgt gacaagatgt ttgtcatagt cccatttttt
     8221 tattttattt ttcaaaacta agaaatacca ggaaagagtt ccttttgttt gaccttttct
     8281 ttcttattga aaacaactat aatatagagt gatgttaaaa gagaagagga atttagtgtg
     8341 cgggtattgt ttattggtga tgtagtaggt tcaatgggac gagagatgat tactgaatat
     8401 cttcctagat tgaagaagaa gtaccgtccg caagtaacga ttgtaaatgg tgagaatgcc
     8461 gcttctggac gtggaatcac agaaaaaatc tataaaaaat ttttgcaaga cggcgtagat
     8521 gtcgtgacga tggggaatca tacgtgggac aaccgcggaa tctttgagtt tgtaaatgaa
     8581 gctaaaaaga tggttcgtcc ggcaaatttt ccggaaggga cgcctggaca agggatggtc
     8641 tttgtcaaag tgaaccaagt cgaactggca gtgatcaaca tgcaggctcg ttcttttatg
     8701 gtggacttgg atgatccttt tcgtaaaatg aatgagctgg tagaagaagc cagaaaacgt
     8761 acgccgatca tttttgtaga ttttcatgga gaaacaacaa gtgaaaaaca agcaatgggc
     8821 tggtttttag atgggaaagt ttcagcagtg gtcggtacac atacacacgt tcagacaaat
     8881 gatgcgcgaa ttttgccaag aggaacagcg tatctgacag acgttgggat gacaggtccc
     8941 tatgatggta ttttgggtat gcgcagagaa cctgtaatcg aaaagtttct gactgcatta
     9001 ccaaaacgtt ttgaagttgt ggaacaaggc cgatcgattt taagcggctg tatcttggaa
     9061 ttggatgata cgacaggtca tgcaaaagaa atccagctga ttcagatcaa cgatgatcga
     9121 ccgttcatgg agtagaaaga gaggcagttt tttgcagcag gagccggaaa ttcaaaaaga
     9181 agtaaggaaa ctgacaaaac ttttaagaga gaatgaaacg atcattcgct acaaagaact
     9241 tgaagaaaag atccagcaaa accagtattt agctgagttg agagaaaaaa tcaaacaagc
     9301 gcaaaaagat gctgttcatt ttgcccacta tgacaaacca gcagcagaaa aagaagcaat
     9361 caaacaagcg gatcaattca tgcaagaatt tgatcagcat ccgcttgttg tagcttatag
     9421 aaaacagctg ttggaagcag atgatctgct tcatcattta acaactatga tacaagaaga
     9481 aatcaatgga caaatagagg aggaaaaaca tgcctcaaaa aactaaaaat actcctatga
     9541 tggaacaata tctaagcatc aaggcccaat accaagatgc ttttttgttc tatcgtttag
     9601 gagactttta tgaactattt tacgaagatg cgatcaaagc gtcacagctt ttggaattaa
     9661 cgttgacgag cagaaatcga aatgcagaag aacctattcc tatgtgcggt gtacctcacc
     9721 atgcagcaca aggatatatc gatgccttga ttgaaaaagg ctataaagta gcgatttgcg
     9781 agcaggtaga agatccaaag acgactaaag ggatggtcaa gcgcgaagtg atccagctag
     9841 tcactcctgg tacagtcatg gacagcaaag gattgtcggc aaaagacaac aattttttaa
     9901 cagctgtagt tagtcaagga aatgaatttg gctttgctta tgccgattta agtacgggag
     9961 aattgaagac ggctcggttg catgatgaag aagctgtttt aaatgaagcc tctgcattgc
    10021 agacaaaaga actcgtatta ggcagtgaga tcactgatac ccttcgtgaa cagctaagcg
    10081 ggcgtttagg gctagtcttt tctcaacaaa atgagatgga agaaaacgcg gaatttagct
    10141 ttttgacaag cgaactagtc gatccgctgg aaaaagaagc aaccggcaaa ctattgactt
    10201 atttatcggt gacacaaaag cggagtttag ctcatatcca aaaagcagta gaataccaac
    10261 cagatcattt tttgaaaatg gattattatt caaaattcaa cctagaatta agccaatcta
    10321 ttcggactgg gaaaaagcac ggcactcttc tatggttgtt agatgaaaca aaaacagcaa
    10381 tgggtggccg tttactaaaa caatggctag accgtccgct tatccaggca aaacaaatta
    10441 aagcaagaca agaaatggtc gcttctttgc tagacagcta ttttgaacgt atcgatttgc
    10501 agtcagcatt aacgaaagtc tatgatctgg aacgcctagc aggtcgagta gctttcggta
    10561 atgtcaatgg gcgagacttg atccagctga aaacttcttt agaacaagtg ccaatgatca
    10621 gagggttgat tgaaggaatc gatcaaggtc aatggcaaag tctgctttca gaaatgcagc
    10681 cgatggacca tctcgtccaa ttgatcgacc aagctatcca agatgatccg ccgttacaaa
    10741 taacggaagg aaacatcatc aaagatggat tcaatgagca gctcgatatg taccgttctg
    10801 ctatgagaaa cggaaagaaa tggttggcag aacttgaagc aaaagagcgt caagaaacag
    10861 gaatcaagaa cttaaaaatc ggatttaacc gcgttttcgg ttattatata gaaattacaa
    10921 aagcaaatct tggaaatgca gaactggaga agtatgaacg aaaacaaact ttagcaaatg
    10981 cagagcgttt catcacacca gaactaaaag aattggagac acaaatcctc gaagcagaag
    11041 aaaaatctgt tgatttagaa tatcagttgt ttttagctgt gagagaagaa gtcaaaaagg
    11101 ctatccagcc gctacaagta cttgcaaaag caatcagtgc agtagatgtg ctacaaagtt
    11161 ttgcaacgat cagcgaacgc tatcagtatg ttcggccaga acttgtcagt gacaagcatc
    11221 agcttctgat caaagacgga cgacatcctg tagtagaaaa agtattagga catcaggaat
    11281 atatccctaa cagcgtagaa atggcagaag acgaaatgat cttgctgatt acaggaccga
    11341 atatgtctgg taaaagtacg tatatgcgac agttggcatt aactgttctg atggcgcaaa
    11401 tgggctgttt cgttccggca aaacaagcag ttttacctat ttttgatcgg atttttaccc
    11461 gaattggtgc aagtgacgac ttaattgctg gacaaagtac ttttatggta gagatgatgg
    11521 aagccaatca agccctgcgt tatgctacgc caaacagttt gattttgttt gacgaactag
    11581 ggcgaggaac agcaacctat gacggaatgg cgttggccca agcaatcatc gaatatatcc
    11641 atcgtcatgt acaagcaaaa acactctttt ctactcatta tcatgaactg acggtacttg
    11701 agaaagaact tccgcagctt aaaaatgtcc atgttggagc cgttgaaaaa gacggagaag
    11761 ttgtcttctt gcataaaatg atggatggac ctgcggataa aagctacggc atacatgtgg
    11821 caaagatcgc aggattgcct tccaatctac tagaacgagc agcagatatc ctgcatacgc
    11881 tagaaaatgg cgataacgga caccatactg ttccagctga agtagaagag aaaactaaaa
    11941 cagccaaaca ggagcaaata aaaccacctg cagaaaaagt aaatcaagac catatacaag
    12001 accgtgtaaa agaagaaaac caacagcttt ctttattcag tgaattatcc gaaaatgaaa
    12061 cagaagtcat tgaatcactg aagcaaataa atttactaga aatgacgcca atggatgcac
    12121 taaacacatt atatgaatta caaaaacaac tgtaggaaga aggcggatat cgatggccaa
    12181 aatccaagaa ttatctgaac gtttagctaa tcagatcgct gcgggagaag tagtggagcg
    12241 accagcttcc gttgtgaaag aattagtgga aaatgcaatt gacgccggca gtactcagat
    12301 tgatatctta gttgaagaag cgggactgcg gacgatccaa gtgattgata acggagaagg
    12361 cattttggca gacgacgtag agaatgcctt caagcggcat gcgacaagta agatccataa
    12421 tcgcgacgat ctttttcgca tacgaacgct gggctttcga ggggaagctt tgccaagtat
    12481 tgcctctgtt tctgaaatga ctctggaaac ggcgaatcag gaagaaaaac aaggcaccta
    12541 tctgtcgctg aaaggcggag aagttattga gcatcgacca gcaccactgc gtcaaggaac
    12601 gaagattacc gtcagcaatc tgtttttcaa tacgccagcc cgcttgaaat acgtgaaaac
    12661 actgcacaca gaattagcga acatcgggga catcgtcaat cgactggcat tgagtcatcc
    12721 atcgattgct tttcgtttag tacatgatgg aaacaaaatg ctggcaactg ctggaaatgg
    12781 cgatctgaaa caaacaattg cgggaatcta cggattatct accgcaaaaa aaatgctgaa
    12841 aatcgaagga aaagatctag attttgagtt atttggctat gtttcattgc ctgaggtgac
    12901 tcgtgccagt aggaattact tatcgacgat catcaatgga cgttttatca agaacttttc
    12961 cttgaataaa gcaatcgttg caggttatgg gtcaaaatta atggtcggtc gtttccctat
    13021 tgctgtattg gaaatcaaaa tggacccgct tttagtagat gtaaatgttc atccgacgaa
    13081 gcaggaagtc cggctgtcga aggaaaaaga actaacagag ctaattagta acgccattca
    13141 aaaagcattg tctcaagaaa atctgattcc aagtgcagcg gataatctac ggtttaagaa
    13201 aaaagtacct gatcagccta aaacagaaca aatcgaaatc gatttgtcct acgcttttga
    13261 agaagaaaaa cctaaaaagc caagtagttt gaattttgat cgagagacag gtaccttttt
    13321 cgtagaagaa ctaaagaaca catttgttga cagaattgtt gataagtctg tggaaaatgt
    13381 tgaaaactat tctggttttt ctgaagaaaa caccacttat ccagaaaaaa cagcgaaaac
    13441 ggtggataag tttggtgaaa atgttgataa ctttgtagaa aaaacagtgg aaaaatctga
    13501 aaagaaagaa tttcccattg tggataacat ggagaaaaca aatgaagaac aagcagataa
    13561 atccgtagaa gaggatgaaa agatttacga ggaagaattg acactccatc ctgaatttga
    13621 tttcactcaa ggaaacgaca aaacattaga acaagccatc aagaaattag aaacggaaaa
    13681 accagtacaa cgttttcctc agttggaata ttttggacag atgcacggaa cgtatctttt
    13741 tgcccaaagt agcgatgggt tgtacatcat tgatcagcat gctgcccaag agcgcattaa
    13801 gtatgaatat ttccgggaaa aaattgggga agtatctgat gatctgcaag aattgcttgt
    13861 tccatttgtg ttagactatc caaacagtga tgctttgaaa ttaaaagagc aaaaacactt
    13921 gctagaagat gcagggattt atttagaaga atttggtcaa aacagcttta ttgtacgggc
    13981 ccatcctact tggtatccca atggagaaga agaatcgatt attcgggaga tgatcgatat
    14041 gctgctgaca actggaagtg tgagtgtaaa aaaattccgt gaagcaacag caatcatgat
    14101 gagttgcaaa cgatcgatta aagccaacca ttatttgaat gaagcacaag cacgtgtgct
    14161 gctgaaggat ctggcacgat gcgaaaatcc tttcaattgt ccccatggcc gtccagtatt
    14221 gattcacttt accaattcgg atatggaaag gatgttcaaa cgaatccaag acccgcatta
    14281 agtcaaagag aagagggaaa acatgaagat tgtattagca tcccaatcac caagaagaaa
    14341 agagttattg gctcatatcg tttcagaatt cgagattgaa cctgctgata tcgatgaaac
    14401 gccatttcca gacgaacagc ccgtcgatta tgttcgtaga atggctgaag aaaaagcacg
    14461 aactgtctgg gaacaagatg aaaaagaaga ccatttagtg attgccagtg acacgactgt
    14521 tgttctcaat caagagatca tgggtaaacc agaagatctg gctgaggctg aattcatgct
    14581 gaaaaaacta agcggggaaa cacatactgt atatacagct gttgttttaa aaacaaagga
    14641 acgagaagaa cggatactag cagaagcaca tgtcactttt tatcctttga cagacgaaga
    14701 gatcaaacgc tacttggaga cgggggatta tgcggataag gcaggggcat acggcatcca
    14761 aaatgctgcg agtgtattcg tcaaagaaat ttctggagat tattacagta tcgtaggatt
    14821 tccgattggt gctgtcaatc aggcactgaa aacattcatt taaacaaaaa agcggactat
    14881 ctgattttcg attgaaaatc catgatagcc cgtttttttt attgaaaaga ttacttatct
    14941 actctgacta agattttact tcagctttac cgactgcttc gcccgggcga acaagtcctg
    15001 attggtcaag agaaagtcct gcaacttttt cattattggt caaagcaaca ataatgtcag
    15061 ttttcttgcc agcttgttct atttctggca aatccatttc agcaatcagg gtctctggtg
    15121 tgacaaggta tccttctttc acgaatacat tgaaaggaac accctttagt tcaacagtat
    15181 ctaatcccat gtgaacaagt acttccagcc cctcattaga aagaatacca atggcatgtt
    15241 ttgtttcaaa gacactcgtc actttaccgt ttactggtgc atagactttg ccgtttgacg
    15301 gttcgacagc ataaccgtca cccatcattt tttgtgagaa aactgggtca tttacttcag
    15361 ttatttcctt gatggtccct gcagcgactg cgaataatgt ttcttttgtt gcaactgccg
    15421 taccagttgc tgaaacaggt tcgaaagact gtggcgttgc tgttgcgcca tttgctgttt
    15481 gaagttgtac atcagcagca ttttcaggaa cagcaggatc aatcttattc aaaattccct
    15541 gacgtctaaa gatgatcgtc aagccaaatg gaatgatgac agcaatgatc attgcgatga
    15601 tgaaaggtac ccatgtttct gcttggatag ctagtattcc tggcaaaccg cctactccga
    15661 tcgcgttagc tcgaacaccc atcaagttag caaacatgcc agctaatcca gagccgacca
    15721 ttgcagcgac gaaaggatag acgtatttca aattgattcc gaacatagca ggttcagtta
    15781 cgcctaagta acaagaaatc attgctggaa tcgagatttg ttcttctttt ttattcccac
    15841 gatgtaagaa gatgatggct aagactgcag agccttgggc gatatttgat aaagcaatca
    15901 tcggccataa attcgttgat ccgaaatctg caatcagctg catatcgatg gcattggtca
    15961 tatggtggag accagtaatc actaaaggag catacaggaa tccgaatacg gcactaaaca
    16021 accagctgat agaagacgtc aatccagtat ttacgatatt tgagatccag cttccgactg
    16081 tccagccgat aggacctaaa ataacgtgtg cagctaaaac agttggtaac aatgaaaaca
    16141 atggaacaaa aatcatcgag atcgactgag ggatatattt gcggaagaag atttctagat
    16201 acgctaacat aaaccctgcc agcatggctg gaataacttg cgcttgataa ccaatcatct
    16261 ggacttgagc aaaaccaaaa tcccaaaatg gaatatctgc tgcggctgtg gaagctacac
    16321 tataagcatt taataattgc ggagaaacta acgtaattcc taaaacgatt cctaatattt
    16381 gtgtagtacc catctttttt gcaatactcc aagtgatacc tactggaaga aaatggaaaa
    16441 ttgcttcacc cggtaaccac aaaaaggcat tgacaccatt ccaaaacttc gagtgttcaa
    16501 cgattgttcc accaagactt tcaaactgga taccttcaag tacatttctg aatccaagga
    16561 tcaatccacc gacaatgatt gcaggaatca gtggtgtaaa gatttctgct aaaacggcaa
    16621 tagcacgttg aacgggatga aggttttgtt ttgcagctgc ttttccttgt tctttggaaa
    16681 ccccttcaac tccagatact gcaacgaagt cgttataaaa agtagaaaca tcgtttccta
    16741 tgatgacttg gaactgtcct gcattcgtga acatcccttt tacgctaggt atatcttcga
    16801 tcgctttttc gtccgctttt cctggatcat tcaggacaaa acgcatacga gtcgcacaat
    16861 gactaactgc agcaatattt tcttttccgc cgatatcatg taacagcttc tcggcatctg
    16921 cttgatattt tgccatatca ataaacccct ttctcttaac ttgtctatgc aagttgtttc
    16981 ttcatttact atactttttt tcggagagaa ttgcaagcgt tttattaaaa agtacgagag
    17041 aaaatgatat cgttttaaaa agcttaaaat aagcttttct taaaaatagg aacattgaaa
    17101 tacaaaaaga gctgtagtat agtgaagaaa tgatggaaga acgagtgagg gaaaaaacat
    17161 gaataagttc aatgaaattt ttttagattt ggaacagaaa attttagcga aagaatatcc
    17221 tccgcattcg cttttaccca gtgagaacca attgatcaaa atttatggtg tttcacgaga
    17281 aacaattaga aaagcgctga atcttttgac tacggaaggt tatattcaaa aaaaacaagg
    17341 aaaaggttcg atcgtactgg atcggaatcg cttcgacttt cctatttctg gattgactag
    17401 ctataaagag ctacaggaga cccaacgtat tccaagtgaa acgatcatcc atacgttaga
    17461 agaaacagaa gtgacaaaag cattgaacga gatcactggc tgggagatcg gtgcgcctgt
    17521 ttggcatttg atacgcgaaa gaaaaatcaa tggcgaagta gttatattag acaccgatta
    17581 tctattaaag gaaatcgttc ctattttaac tccagcacaa gcacaaggat cgatctatga
    17641 atattttgaa aatgagcttt ctttgacgat tgcttacgcg caaaaggaga tcacagtaga
    17701 agaagtaacg gaaatcatga aaacagcgat ggatcttcac gatgacactt atgcagtagt
    17761 agtcagaagc ctcgttcatc tggaagatac ccgctgtttc gagtattctg agtcggttca
    17821 ccgattagat aaattccgtt tcgttgagtt tgcccgacgc cgaaaagtgt aaatagttca
    17881 aaagaaagca aattgttggc atctgtccac tttggcgcta tgataggatc acaaaggggg
    17941 catttttaat ggataaacca ataagaccag aaaaagaaga actgaaagaa aagttatcac
    18001 ccatggctta tgcagtcaca caagaaaatg caacagaacg accatttagc gggaaatatg
    18061 atgattttta cgaaaagggg atctatgtag atatcgtcag cggtgaaccg ttattcagct
    18121 ctgcagaaaa atatgatgca ggttgtggct ggccatcatt cagcaaacca ataacgaaaa
    18181 gacaagtgcg cgaaaaagcc gatttttctc atggcatgca tcgaatagaa gttcgaagca
    18241 aagaagcaga ttctcatctc ggacatgtgt ttaccgatgg accagtagat caaggtggtc
    18301 tacgttactg catcaattct gcctcactga aattcattcc atatgaaaag atggatgaat
    18361 taggttatgg ggaattcaaa tcacttgtag aataatggaa atacacaaag agcggtacaa
    18421 tacggggatt tactcgatcg tccgctcttt ttttattcaa gcgattgcta tttgaaagaa
    18481 acgctcccta gactcctttt ttcacaaggt gaaatgtgct acaataaagg gaacgtatgt
    18541 gtgcaaaaga aagaggacta gaatatgtat gaatatctga caggtgtggt tacctttatc
    18601 aacccctatt acatagtagt agaaaccaat ggtatcggct accagatcgc actaggaaat
    18661 ccttaccgct acagtagcaa actaaatcaa aaaataaaaa tttatgtcca tcaggtaata
    18721 cgtgaagatg cgcatcttct gtatggattt gattcgctag aagaaaagca actgtttttg
    18781 cgattagtaa gtgtttcagg aatcggtccg aaaagtgccc ttgcaatcat ggcaagcgaa
    18841 gaccactccg gtttgattca agcagtagaa tccagtgatg tcacttattt gacgaaattt
    18901 ccaggagtag ggaaaaagac agcacaacaa atgatcttgg atctaaaagg aaaattcggt
    18961 gagctgagta tcgatacacc ttttagtcta tttgatgaag caaacacaaa agacgctaca
    19021 gctctatctg aagcaatgga agctctctcg gctcttggtt acagtgatcg agaaatcaaa
    19081 cgtgtagaaa aacaattaaa agaagtagat aatcagacaa cggatgagta tctacgccaa
    19141 gcactcaagc taatgatgaa aaaataagga ggagaccaaa tgacagatga atacttgtta
    19201 tcaccagaat ctggcgaaaa tgaactgagt ttggaaaaat ctcttcgacc acagctgctt
    19261 tctcaatata tcggacagag aaaagtcaaa caagaacttc agatttacat cgaagctgcc
    19321 agaaatcggg aagaaccttt agatcatgtt ctgttgtacg ggcctcctgg attaggaaaa
    19381 acgacgatgg ccatggtcat tgctaatgag atgaccgtaa atattcgtac gacgagtggc
    19441 cctgctatcg aacgtccggg tgacttagta gcaatcttga atgaactgga agcaggggat
    19501 gtcctgttta tcgatgagat ccatcgatta cctagagtgg tagaagagat gctttattca
    19561 gctatggaag atttctatgt agatatcatg gtaggacaag ggccaaccgc acatccggtt
    19621 catttccctc ttcctccctt tactttgatt ggcgcgacga cacgggcagg tatgctttct
    19681 gcacctttac gagatcgatt tggcatcatt tctcatatgg aatattatga cgaacaggat
    19741 ctgcaggaga tcgttttacg ttcttcggat atttttcaaa cagagatcat tgaagaaggg
    19801 gcattggaaa ttgctcgccg atcacgagga acgcctagaa tcgctaatcg cttgctcaaa
    19861 cgggttcgtg attttgcgca agtccaagga gacgggaaaa tcgatcgtcc tatagcggat
    19921 caggcactta ctttgctaca ggtcgatcag gctggattgg attatgttga ccagaaattg
    19981 ttgcgaacaa tgatcgagtt atatggcggc ggaccagtag ggttaagtac gctttcagta
    20041 aacataggag aagagcgtga gacggtagaa gatatgtatg aaccgtatct gatccaaaaa
    20101 ggatttttaa agcgtacacc tagagggcga attgctactg cttatgccta tgaacatttt
    20161 ggttacgact atcatatatg atttttgctt ttagattgga ggaaaatgaa tgagtgatac
    20221 aacacgtacg aaacaattga tcaaaaacgt attgattgat ttgtgccaaa cgcaatcttt
    20281 tcgaaaaatc agcgtccaaa aaatcgcaaa cgaagcaaaa atcaatcgac aaacatttta
    20341 ttatcatttt acagataaat acgatttgct tcgttgggtc tattgtgagg atgcattgca
    20401 ttatttagat ccacaatgtc tttcacttga taattgggaa gagcaagcat tgaaaatgct
    20461 gaaagcaatt gctgagaaga aagaatttta tgcaaatact gtgctttctg acccagaaat
    20521 tttacaaaaa gagttttctc aactgatcca aaaatcattt atcaagattt ttgaacaaat
    20581 ggatgaagaa agacaacttt ctgcaagaga caaactattt tatgctcgtt ttttttctta
    20641 cggttgcagt ggtgtattag tcaattggat cacgaatgaa tatgaagaaa caccgatgga
    20701 aatcgctatg cagcttttcc gtttagccaa ggatacggaa ttatattctt atcgtcttta
    20761 tgcaaaagaa gagttggaag aacagtaata gaaaaatttt ttgttggaaa agcaataatc
    20821 gctaaaagga gatggggaaa tgacaaaaat tttatttgtt tgtttgggaa atatttgccg
    20881 ttcaccgatg gcagaaggct tgctgagaaa acgaatagca ttagaaggaa gggaagcaga
    20941 attttttgtg gattctgctg ctacaagcac gtatgaagtt ggaaagacac cgcaccctgg
    21001 aacgaaaaaa atattaaacc aagaaaaagt agatatgacg aatatggttg ctcggcaaat
    21061 cacaccccac gattttgaaa cttttgattg gatcattggc atggatcaag aaaatgtaga
    21121 agaactgaaa cgaagagcac cacgctcagc gcaggggaaa atccatttgt ttttaagtag
    21181 cattcctgga aaagaaaaag aaaatgttcc cgacccatac tataccaata actttgatga
    21241 gacatatcac ttgatcacag aaggcctgaa tcattggtgg aatatttgga ttgatgaaaa
    21301 taaaataaca aacaatttgt aaagttaacg ctttcttttt aaggcgatgt tagagcattt
    21361 ccttgttttt ttgtaaaatg ttaggtaaaa taaaattaat taagtaacac tttcttagct
    21421 aaaggaggag tgcattcgat gaacgaagag acagtatcgc caatgaagaa gcttacgaag
    21481 ttagttactc atacttcgta tcaacttttt gattcttttg taaatgacac tgaagaacat
    21541 gctaagaatg tacgattgca aggaaagttt attcttgagc tgcaaaaagc tgctactgaa
    21601 catagtctag ttatcttaca agtaagagca aatcgtttga gtagcaagta tgaaacgatc
    21661 tcaggctggg tggcgacaaa aacggtcgaa aaagaccgag tgatgatccg cctacaaaac
    21721 gaagagcagc agatccggat ggttcctgta gaacaaattg aaaaaataac aatcctttca
    21781 ccagcagggg aacaggaacg gttatcaaaa taatttatac cagatagaaa agcacgtatg
    21841 agcttgtacc atcaatcatt actaatcaaa aataaccgaa tgctttaagc tgatatcagt
    21901 aaaacggaac gttttaggat gagtatcata gcatgacagc attcggttga ttagttgaat
    21961 cgattggatg gtacaagttt ttttgataaa aaaaggtcct gctagccggg gagctagcag
    22021 gataaggagt taaaaatgaa aaagtgttgt tagggttgtt tgttggtatg cttatataat
    22081 agtcattagt tgtgaatatt ttgtgacgaa agttttcgaa agttgttaag tt
//
LOCUS       DAFBVQ010000046        21503 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.047, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000046 DAFBVQ010000000
VERSION     DAFBVQ010000046.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 21503)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 21503)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..21503
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.047"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            5..403
                     /locus_tag="LLC22_001920"
     CDS             5..403
                     /locus_tag="LLC22_001920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIA"
                     /protein_id="HBK5435196.1"
                     /translation="MTIFETVVTDVGIEAEVFRKEKIMILFGDEAPETLTDYCYKIEL
                     NQVRKEITCDMKLCFDKQMYVITAVGDVVQTNLNELGHITIKFDGSHEPELPGTMYVE
                     DKEMPHLRKGTIIKIDQEDQNGGKLYGNHA"
     gene            387..1082
                     /locus_tag="LLC22_001921"
     CDS             387..1082
                     /locus_tag="LLC22_001921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fructose-6-phosphate aldolase"
                     /protein_id="HBK5435197.1"
                     /translation="MEIMLDTANTKSIYSCQQFLNLTGVTTNPTILKKEGASNFFSHM
                     KEIKKIIGQIPIHIQTIGRTEEEMIEDARVIIEELGKDTFIKVPVNQAGLQAIKKLKK
                     EGYLITGTAIYTELQGYLAINNGADYIAPYYNRMQNQGIDAMKVIDSLRTEIERTQRP
                     TKILAASFKNCEQVTTAIRSGAHAITLGKELLDQVLEMPSIDKAVRGFQEDWVQTFQA
                     ETIGELKKVADYF"
     gene            complement(1666..2553)
                     /locus_tag="LLC22_001922"
     CDS             complement(1666..2553)
                     /locus_tag="LLC22_001922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidyl-prolyl cis-trans isomerase"
                     /protein_id="HBK5435198.1"
                     /translation="MGNFLKKQLLIMCLSACAILLFSGCSKSNETIATFKGGTLTVQD
                     FYDNPKVKSNNQTLLKKMIVFKAFDDVYGKEISSKEVTKEYNEQIKKLGPNYKEQLKA
                     VGQTEETYKKLFKQMLAFQYGLKANVKLTDKDLDTAWKEFYPEVSTQIILFSTKEEAD
                     KAKKEANEGENFSKLVQAYGKNKTLKETDGKMNFDSTNPEIPTEVKKAAFKLKNGEVS
                     DIIPVTDPTTYQQSYYLVKMVKKQDKGSNKDKYKSELEKIATEAKTLDTEFMDKTIRK
                     VMKKDNVTIKDPYVKNIFK"
     gene            2738..3577
                     /locus_tag="LLC22_001923"
     CDS             2738..3577
                     /locus_tag="LLC22_001923"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378019.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK5435199.1"
                     /translation="MIRIIRLIGSVLIVLVGFVLGILVNNALADMFIGNSEWIGAIAG
                     TVGHLAVFLLALFLASKVEGKRIEDYGVSVRGKDWGYLAGGLVVGIGVFLLITSPLYL
                     TGAYRLDSGNANIVPLITSFILFIAVGASEELLFRGFFQHQMLRFGPLIAMIGSAALF
                     ALLHGLNPNMTFLAVFNIFLAGCFFSALIYSTGSLFTAIGAHITWNWTQGAILGIPVS
                     GTQEQGFFSTLIQSQNTIITGGNFGAEASISTTLFLLVLIVGLLLYAYKTKRMKKYTA
                     VYQ"
     gene            3773..4747
                     /gene="sgrA"
                     /locus_tag="LLC22_001924"
     CDS             3773..4747
                     /gene="sgrA"
                     /locus_tag="LLC22_001924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG-anchored fibrinogen/nidogen-binding
                     adhesin SgrA"
                     /protein_id="HBK5435200.1"
                     /translation="MKKTATVLFVILGLSIIAAMIGISTSANERANENLSFTVKTDRI
                     VYDMTQQVITIPVKPNKSVNASDVHAVLTYGWDGNGSSEKVIGEVYLKDVQWTAGIEY
                     TIMISAELSIDEIKSKDKVDLIVFYDGQMTITENLKPSSWTVVGPPSSTDSTSSESST
                     ENTSGESSTESTSSESSTENTSSESSTESTSSESSTGSTSSESSTESTSSESSTGSMS
                     SESSTGSTSSESSTGKVNNELDLVPIIPTKEQKRNAGSNLKSVLKQPDFVSRGIDHQE
                     KAKETDNRKSDLPETGSRTLNKLITWMGVLLILIVGASYFRSLFHRVK"
     gene            5045..5401
                     /locus_tag="LLC22_001925"
     CDS             5045..5401
                     /locus_tag="LLC22_001925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435201.1"
                     /translation="MFEEFIDINERQVYQFLNYCYERDEKLYVVKDIALDLNYTLAKM
                     NSVIQQAESFCERYPEYKLSFLSENKMIKVEFSSQFLLSKVYSILLEGTIGYILLDSL
                     YKGTYQSLENLSQKII"
     gene            5404..6561
                     /locus_tag="LLC22_001926"
     CDS             5404..6561
                     /locus_tag="LLC22_001926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435202.1"
                     /translation="MRTIQRKLRELNTILKNYHLSCSLKKGNPIEGEEYRIRYFFHLM
                     YWQSFDENHSDILSSIKNKRQLLEKFAKHAPYTRSIDRKKWISLLRISLQRMKQGHSI
                     TYVPEEMNKFVHPLITKEEFTHYILEPFFEANFWSMNHITPTEQAYLYFMFGVMNTYL
                     EEDLLDTPDKVQESWGWIESSIVENFEKNFKICFTTSEKNYLYVNLAMIHLYSRVFGT
                     KKKVDAFGKSAEDRDFQHIFPVMYPIMQQFFSGVARRIPELNTYYEKNRRLIFQYCML
                     VRDIFIKHEQPVIFYIQSKYGKTQELWAKKRILSMTERPIKYSASADQLPDIVISDYP
                     IDKKAYDQTNTQIFYWNGQPTKNDWARLKAEIIKIRNEKNRSILEKLDFVN"
     gene            complement(6587..7027)
                     /locus_tag="LLC22_001927"
     CDS             complement(6587..7027)
                     /locus_tag="LLC22_001927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331724.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Spx/MgsR family RNA polymerase-binding
                     regulatory protein"
                     /protein_id="HBK5435203.1"
                     /translation="MMIKLYTGSGCSSSRRAKRWLIVHDIPFIEQNLIRQPLTKNEFI
                     HLLKLTNNGVTEMLSTHSISYKNLVHRIDELSLSELYIEIRTSPSLLKKPIIYDQSAK
                     LLTGFSEDKIRMFLSKTKRKQELNELLLSGHLVDFKENNLFAMS"
     gene            7187..7693
                     /locus_tag="LLC22_001928"
     CDS             7187..7693
                     /locus_tag="LLC22_001928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5435204.1"
                     /translation="MSNTADAIVVIDLQKGVCFDSSPIHELETVTALVNKRIKTYETI
                     GKPVIFVQHEDAQLVPQTKPWELLSELSIPEHSYFVRKTHANSFYKTNLSVLLTELDC
                     HSIELCGAQAEYCIDTTVKFAHGLGYQLMMCRGATTTYDNPFMKAKETIAFYEKIWDK
                     RFLTFLEQ"
     gene            7861..9774
                     /locus_tag="LLC22_001929"
     CDS             7861..9774
                     /locus_tag="LLC22_001929"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MucBP domain-containing protein"
                     /protein_id="HBK5435205.1"
                     /translation="MNSLRTKQVLKGALVILFAVSTSVPQWTVYGESISSESESREVE
                     TTETTDAGNETKSSTSQTETNTETTVETSVTSTDQETTATTDNQQTEEATATKMSNDE
                     SSSAKVSDKENGTENDDIGKGENFNGKEYLNYFGKQMTEILNGPTEDIKSKLIELLVT
                     ELAVNDYGVDKEIIKHLIATYLLYDIAFAKNSVLMSMLGGTDDGTTPTENTGFYPNTK
                     QLHQTVLNKQDGKMMDVYAYYVDQGSDKTVMIHGGFRGNWNNGIVTEEYNDFYKAGYN
                     LLFVDSRATGNSGGDYVTYGQYESDDVLYWINQEVRERPSQKILLYGGSMGAATMMSV
                     LAKDIPVNVKGIIENCGFASIDEQLRFTYSQTVAPALPDAIKNQLDIIGDQEHEDLFM
                     GLLKQYYFDQEMHLDTKAALPTIGMSDSLPKLIIHGTADDVVPVSNAQKLYELSGGYK
                     DLLLVEGAGHGKAQEVDHAAYTKHVTDFLKVVFHDQINVKYVDENNKSLLKDQDEIQL
                     YGAYGENYMTEQKTFEGYELANVEGPTEGIFNETIPTIIFYYKKIPVAPPKKQDPTEN
                     ADNKGKNEPREDQSSDDTQPIQMTVKVQKKTDAKKRMLPKTGEKKHSLLIYSGGFLSV
                     STIITWIWRRKRG"
     gene            9779..10780
                     /locus_tag="LLC22_001930"
     CDS             9779..10780
                     /locus_tag="LLC22_001930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300989.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alpha/beta hydrolase"
                     /protein_id="HBK5435206.1"
                     /translation="MKWFKRIVIAVPVIIVVILVTVFLINQITPKPISLLVRKQFDTS
                     EKEQVYARPDDFQQKIEQIDIKKEISYPSKYKNNNMDIYTPKVEKKKLPILFWMHGGA
                     YVGGDKNDCRDYLEYLCSDTQQIIVNIDYERSPEAKHPTPVIQLNEAIQAAKKEIKDQ
                     ADWSNISIGGNSAGAQISGEYLLALQNEEIKKADHLDPTLENKQITKFISLSGLLDPS
                     ALTQVSDKISSFLYEKCGWAYFDNKDFEQSEKVKSLALVRHADRWTQNTFLTDGNTNT
                     FTKQMEEVTSVFEKAGVKVTKVDYAEKNAVLNHEYQFDFSNKQAQETYQKLVMFFKE"
     gene            complement(10982..11188)
                     /locus_tag="LLC22_001931"
     CDS             complement(10982..11188)
                     /locus_tag="LLC22_001931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3955 domain-containing protein"
                     /protein_id="HBK5435207.1"
                     /translation="MKAIHISLLFFASALILFAIHLCSQPYINNNGILVEPAFFCLPL
                     GFLSLLASAGFGFVAFFKRSKQQI"
     gene            complement(11834..12682)
                     /locus_tag="LLC22_001932"
     CDS             complement(11834..12682)
                     /locus_tag="LLC22_001932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338311.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5435208.1"
                     /translation="MSVSIRLQIKTMYNDFSPKEQAIADYILENPSKVSHSPISNLAS
                     ELGIADSTFFQFTKKLGYNGFKDFKMAMLIQENDLSAISIHENIQKTDTELTMAQKVF
                     ESSISTLNDTKKLLQQKDLKKAATIINESKRVYFFGVGGSEIVATDAYHKFLRSPIAT
                     SHSTDYHIQLMEASLLTEKDCAVLISHTGQSKETIHIAETVRKTGAKTIVITSQANSS
                     LAKLGDVVFISISEETEFRSEALASRISQLSILDSLYVILMFYNEKESRRSIAKVRHT
                     ISEIKE"
     gene            12681..13748
                     /gene="gnd"
                     /locus_tag="LLC22_001933"
     CDS             12681..13748
                     /gene="gnd"
                     /locus_tag="LLC22_001933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="decarboxylating 6-phosphogluconate
                     dehydrogenase"
                     /protein_id="HBK5435209.1"
                     /translation="MRIPHFHNKIIIFSVLINVKDTRRVGKNQTKNIFVKSIYKKIFL
                     YNEGIRNGGAIMEIGVIGLGKMGLNLALNLKEHHHKVQGLDISSTAVSQARENDIPAY
                     QEISEFLATFEQKKIIWLMLPAGEITENMLRKLFPKLGPGDIIIEGGNSYYKDSIRRA
                     EEFQKNEIGYLDCGTSGGIEGARHQACLMIGGDKETFLSVEQLFKDVAIERGYLYAGA
                     SGSGHFLKMIHNGIEYGMMQAIGEGFQLVQKSEYAFDLEQVARVWNHGSVIRGWLMEI
                     MEDQLNEHPNLSNYRGIVSASGEAKWTVETALEMAVPVPVIATSLFMRNLSQEEDSFS
                     AKVVSALRNGFGGHEIVEKGE"
     gene            13750..14751
                     /locus_tag="LLC22_001934"
     CDS             13750..14751
                     /locus_tag="LLC22_001934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296641.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydroxyacid dehydrogenase"
                     /protein_id="HBK5435210.1"
                     /translation="MPDYHIAIVNSSSFGRVFPHHLERLKSVGDVHFFTVDQEIPGKE
                     LAELLKGFNIIIASVTPFFRRDFFENKDELLLISRHGIGYNNIDLKAAKEHQTIVSII
                     PALVERNAVAENNITNLLSMLRRTTQAQARVKDDRWEDRAEFVGRTLFNKTVGVIGAG
                     NTGSGVIEILRNGFRCDVLAYDPYKSDLYIESFGAKKVELQELLEQSDIICLCANLTE
                     ENYHMISDKEVDQMKENVYLSNSARGALVDEEAMINGLKSGKIAGYATDVLEEEPGRQ
                     DHPYLAFEQVVITPHISAYTRECLEAMGEKCVRDVEQISQHLLPERSVQTKSNYIKG"
     gene            14748..15032
                     /locus_tag="LLC22_001935"
     CDS             14748..15032
                     /locus_tag="LLC22_001935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alcohol dehydrogenase"
                     /protein_id="HBK5435211.1"
                     /translation="MMKKMVNGLKVKTGPQFYLYEEGGISKVSDLLKSYGAKRVLVTH
                     GTVSWEKALPKLVFLNDETIQFFYHRYSGECSYAEARRIATIIKKMKSIS"
     gene            15065..15862
                     /locus_tag="LLC22_001936"
     CDS             15065..15862
                     /locus_tag="LLC22_001936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303106.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBK5435212.1"
                     /translation="MGYSANLARIDFGVIPTLASNCAPWTPLAVMYKENGQAEGKTEH
                     FYRQAAFFITDPQLVIDSPVPYFIAGLADTLAKWYESELILEQDFLQDESFLKLAQDT
                     AKICKEEILNHSAKAIQDMAQRKLTSEFKQLSEIIFAVAGLVGGLGDKYARNVAAHAM
                     HDAISKYIPESHRFLHGEKVAYGIFYQLALEGRWEKIDELYPLYRELELPVSLEQMGL
                     FPKDKQIIDKMAEFIDSKEKVHLIPIEVTQKSLIQSMMELEGYIRKI"
     gene            15876..16709
                     /locus_tag="LLC22_001937"
     CDS             15876..16709
                     /locus_tag="LLC22_001937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5435213.1"
                     /translation="METLSVVQSLLIALWVAAVMSRWLGGGATLTLRFSPLMTGLVVG
                     LIMGEVAQAMIVTAALQMIYMGVFSPGGSMPAEPSIAAAIAVPVALLGDLSPEAAIAV
                     AVPVGLLGSYLYQFRFFINTFLGKYTDKAVEDLNTKAMARSIILYPTVASFLLFVPLV
                     FIALYLGAPLIADVIKALEGTVVIHILEVVGGGLAAIGIATTVYVIGRKDYLVFFFLA
                     YFMSVVLKSLDITMVTYAIFGIIIALIFVQSQKGKQVQPATSNNNSASFDDEDDYDDG
                     F"
     gene            16727..17584
                     /locus_tag="LLC22_001938"
     CDS             16727..17584
                     /locus_tag="LLC22_001938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5435214.1"
                     /translation="MAEIMDNQTGAPEEITKKDVTKAYLRWHFANEIPHSFERYLAPS
                     LLYGMMPILKKLYKDEDSLKAAYKRQLLFFNTQLSWGGGVITGLMSSMEQQRAEEEYE
                     EKEILMQDDLMYNTKAGLMGALAGIGDAIDSGTVQYIFIAIAVPWAQQGSPLGALFPF
                     ICFGLYQVLLGVFFARQAFTMGRNATGLKQNTGVQTAIEMLSVLGLFMMGVLAGNYVK
                     VESSLKFAISGREFVIQEILDQIVPGILPLAVVMGVYLFYTKKGLKVTQALLWLTGIL
                     IVLAGIGIL"
     gene            17606..18115
                     /locus_tag="LLC22_001939"
     CDS             17606..18115
                     /locus_tag="LLC22_001939"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296648.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5435215.1"
                     /translation="MGVVNLARVDERLIHGQVMVTLSQKSGVNSIFVVDEVVAKDKFM
                     RDLYKNAGSRTGQKTIVITPEKAKFYWDEYQFKEYNCILIAKTVQTIYDLVKHGIPME
                     ELNIGGIAQKNPDTDLLVTKSVYLNKSDAEKLKEMNEQYGVKNIYFQATPSAPKTGLK
                     DVLNKFDLS"
     gene            18152..18553
                     /locus_tag="LLC22_001940"
     CDS             18152..18553
                     /locus_tag="LLC22_001940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346685.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435216.1"
                     /translation="MKKNELFRDWEFRYRYIYRKRRTKKSKQRFLSALVSDIYSMRTD
                     VTVIAYDTLAYRSKNIYVGDIEKAEKVICTYYDTPVHALGSYFMFDWKDQRKKTIYSI
                     LLSFILLFSLGWWGMMIYNKNPHHVFDLLSV"
     gene            18665..19018
                     /locus_tag="LLC22_001941"
     CDS             18665..19018
                     /locus_tag="LLC22_001941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321678.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435217.1"
                     /translation="MLEMIRTIDDPSVAYAFVDEGCYGEKGLDSVRSGMKKEAILFYL
                     DSVGADTPLQFSGNYFSNKEQWLKQVDKLKEKNVNYIFSARKKQAQFFYLTKTDLRGK
                     TFNWQNANQIIALFR"
     gene            19052..19495
                     /locus_tag="LLC22_001942"
     CDS             19052..19495
                     /locus_tag="LLC22_001942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339224.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBK5435218.1"
                     /translation="MLEIMIVTHGKLSEGLKDAAEVIVGTSSHIETMCLESGEDIQTF
                     GEKVKEKLTMINTAEPMLVFVDLISASPYNQALLAVNELTEEKKAATYVIGGVNLPML
                     LEAINHQMLHTPIEEAVEQIVKQGKDNLTVWHASAEEKKLDEDDF"
     gene            19512..20597
                     /gene="uxuA"
                     /locus_tag="LLC22_001943"
     CDS             19512..20597
                     /gene="uxuA"
                     /locus_tag="LLC22_001943"
                     /EC_number="4.2.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="mannonate dehydratase"
                     /protein_id="HBK5435219.1"
                     /translation="MKWGFRWYGEKGDSIPLKYVRQIPGINGIIGTLLTKMPGDVWEI
                     SEIEELKASVESQGLELLGIESVAIHDAIKAGTDERDYYIDNYIRTIKNLSRCGVRLI
                     CYSFKPIFGWAKTDLFNENNDGSYSLLYDQKIVDQMEPGEMYQLIHSQSKGFKLPGWE
                     EERLKKFAQLEKLYEGMTEEELFENLTYFLEKVIPVCEKADVKMAIHPDDPPWELFGF
                     PRVTKNLGDLKKILNAVDSPYNGLTLCTGSLGANPENDLVEIIHEVGSRIHFVHFRNV
                     EFLGERKFKETAHPSTEGSLDMYHIMKALVQEGFDGPIRPDHGRTVWGEVAMPGYGLY
                     DRAMGLTYMQGLYEAISKEKPLGEHYE"
     gene            20590..21303
                     /locus_tag="LLC22_001944"
     CDS             20590..21303
                     /locus_tag="LLC22_001944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5435220.1"
                     /translation="MNKIKLFIFDMDGLLLETGRLAYRAYVKSAQKYDYEMRKEVYYL
                     LTGQTEMAIREQMGILYGEDVPYIKWREAINQYKEKIVKEDKRVYTKKGAEEILSFAK
                     ERGIHTIVASSNTRVKVEMYLKMENLYALFDQIISGDDVKKGKPEPEIFLKACSKMNI
                     PPSEALVFEDSIAGIEAARRAGILSFLIKDHLIGLPDHNGKHKLKVDVSLYESNKADY
                     EFYDLHQAKRFLESKGLYL"
BASE COUNT         7400 a         3301 c         4491 g         6311 t
ORIGIN      
        1 agagatgacg atctttgaaa cggttgtaac agatgttggt atagaagcag aagtattcag
       61 gaaagaaaaa ataatgattt tatttggaga tgaagcaccg gaaacattaa cagattattg
      121 ttataagatt gaattgaatc aggtaagaaa agaaataact tgtgatatga agctctgttt
      181 tgataaacaa atgtatgtaa tcacagcagt aggagatgtt gtccaaacta atttgaatga
      241 attaggacat atcacgataa aatttgatgg atctcatgag ccggaacttc caggaacaat
      301 gtatgtagaa gataaggaaa tgccgcattt aagaaagggg acaatcatta aaatcgatca
      361 agaggatcag aatgggggaa agctatatgg aaatcatgct tgatacagca aatacaaaaa
      421 gtatttattc ttgtcaacag tttttgaatt taacaggcgt aacaacaaat cctacaattc
      481 tgaaaaaaga aggagcgtca aacttcttct cgcatatgaa agaaatcaaa aaaataatcg
      541 gacagattcc tatccatatt cagacaatag gaagaacgga agaagaaatg atagaggatg
      601 ctcgagttat catagaagaa ctgggaaaag atacgtttat caaggtgccg gtgaatcaag
      661 caggccttca agcgatcaaa aagttgaaaa aagaaggtta tttgattacc ggtacagcta
      721 tttacacaga attacaaggg tatttagcta ttaataatgg agcagattat attgcacctt
      781 attataacag gatgcaaaat caaggcattg atgctatgaa agtgattgat tcgttgcgga
      841 ctgagatcga acgtacgcaa agaccaacaa aaatattagc agctagtttc aaaaattgtg
      901 aacaagtcac tacagccatt cgatctggag ctcatgcgat aacgttaggt aaagagctac
      961 tagatcaagt attagagatg ccctcgattg ataaagcagt gaggggcttc caagaagatt
     1021 gggtgcaaac tttccaagca gaaacgattg gtgaactaaa aaaggtcgct gattacttct
     1081 gaatcaattt ctccataaaa taaacgatag ccttctcgaa aactcgagga ggctatctga
     1141 cgattcaata ttcattaatt taaagtttgg gtgactatta cttatttctc atttaaacga
     1201 tgtattccct aacctctaat acatccttgt aactctgaag ttacgccagt tttgaataaa
     1261 tttcataaaa acaaatgaaa agtgtcgcat aaaaatatct ttcgtgtttc tctagtataa
     1321 cagaataaga ggaacaagtc cagaagggat atttttagtc ttttttaaaa taacttttca
     1381 gtcgagtttg agtttatgat agttgttttt gaagcgatac ggcaagtgaa aaaataggga
     1441 agcatgaaag aatctactta atggcgcatt gattcatgtg atagaaataa aaaacttttt
     1501 taaattatat cctcatgatt gtaacaaatc cagtgatttg ttttggtaca aataaaaaaa
     1561 ggccccgatg aagttgtggc aaaagtggtt tgcctcaaaa ataagaagga atttccaaaa
     1621 atcacttctc aaattttgcc acatccccaa ttgggtcaaa tttgtttatt tgaatatatt
     1681 ttttacataa ggatctttaa tagttacatt gtcttttttc atcactttac ggattgtttt
     1741 atccatgaat tccgtatcaa gagtttttgc ttcggtagca attttttcta gctcagattt
     1801 gtatttgtct ttattagaac ctttatcctg tttttttacc atttttacta gataatagct
     1861 ttgctgataa gtcgttggat ctgttacagg aatgatatca gaaacttccc cgttttttag
     1921 tttaaatgct gcttttttta cttcagtagg aatctctgga ttggttgaat caaaattcat
     1981 ttttccatca gtttccttta atgttttatt ttttccataa gcttgaacaa gcttggagaa
     2041 attttcccct tcatttgctt ctttttttgc tttatctgct tcttctttag tcgaaaatag
     2101 aatgatctgt gtactaactt ctggatagaa ttctttccaa gcagtgtcta gatctttatc
     2161 tgttaatttt acattggctt tcaaaccgta ttggaaagcc agcatctgtt taaagagttt
     2221 cttatatgtc tcttctgttt ggccaactgc ttttaattgt tccttgtagt ttggaccgag
     2281 ttttttgatt tgttcattat attcttttgt tacttccttt gaagaaatct cttttccgta
     2341 tacatcatca aatgctttga agacaatcat tttttttaat agtgtttgat tatttgattt
     2401 aacttttggg ttatcataaa aatcctgaac tgtaagtgtt ccacctttaa acgttgcaat
     2461 cgtttcattg gacttgctac aacctgagaa tagtaaaatt gcacatgctg aaaggcacat
     2521 aattagtagt tgttttttca aaaaatttcc catcctttcc ttattaaaaa cagtctaaca
     2581 gaagaattag ggagacagtc tttcattttc gtaaggttgc tgtagatatt cttagttcgt
     2641 aaaaatctat tctctctatg atggagaaca tttacatagt tttcacgaga caagaaagaa
     2701 aagggttgtt aaacttaata taaaggaggg atgaaagatg atcaggatta ttcggttgat
     2761 tggatctgtt ttaatagtct tagttggttt tgttttagga attcttgtca ataatgcact
     2821 tgcggatatg tttattggaa atagtgaatg gattggagca attgccggta cggtcggaca
     2881 tttagctgtt tttttactag ctttatttct tgctagtaag gtcgaaggaa aaagaataga
     2941 agattatggt gtttctgttc gaggaaaaga ctgggggtat ttagcgggag gtctcgttgt
     3001 tggaattgga gtgtttctgc ttattactag tccattatat ttgacggggg cgtatcggtt
     3061 agattcagga aacgcaaaca ttgtgccgct gataacgagt tttattttat ttattgcagt
     3121 gggggcatca gaagagcttt tattccgtgg cttttttcag catcagatgc ttagatttgg
     3181 tccgttaata gcaatgattg gatctgctgc attatttgct cttttgcacg gattgaatcc
     3241 taacatgaca tttctggcag ttttcaatat ctttttagca ggttgctttt tcagcgcact
     3301 tatctacagt acaggaagtt tatttacggc tattggtgct catattactt ggaattggac
     3361 acaaggagct attttgggta taccagtcag cggaacgcaa gaacaaggtt ttttctccac
     3421 tctgatccaa tcgcaaaata caataattac tgggggaaac tttggggctg aagcatctat
     3481 atcaactaca ttattcttgt tagtcttgat tgttggtttg ttactctatg catataaaac
     3541 aaagcggatg aagaaataca ctgctgttta tcaataaaag atgaagaaag caaggctgat
     3601 atcggtcttg cttttttaag tctgtcattg attaaacgaa aaagtaaaca aattcaagcg
     3661 aatacacgac atcttttgtt agattttcac aactgactgt cgtgttctca tcattttcat
     3721 tttatataat tcctttatca aatagaaggt aattatatgg agagtgatag aaatgaagaa
     3781 aacagcgacc gtattatttg ttattcttgg gctgagtata attgcagcaa tgattggaat
     3841 cagtacttct gcaaatgaac gggcaaatga gaatctttca tttactgtga aaactgatcg
     3901 gattgtttat gacatgacac aacaagtcat tactattcca gtcaaaccaa acaaaagcgt
     3961 gaatgctagt gatgtacatg ctgttctaac atatggttgg gatggtaatg gaagttcaga
     4021 aaaagttatt ggggaagttt atttaaaaga cgtacaatgg accgctggta ttgagtatac
     4081 aataatgatt tctgcagaac tatcgattga tgagatcaag agtaaagata aagttgattt
     4141 gattgttttt tatgatggac agatgacgat cacggagaat ttgaaaccaa gcagttggac
     4201 agttgttgga ccgccaagca gtacggatag cacaagtagt gaaagcagta cagaaaacac
     4261 gagcggtgaa agcagtacag agagtacgag cagtgaaagt agcacagaaa acacgagcag
     4321 cgaaagcagt acggagagta cgagtagtga aagtagcaca ggaagcacga gcagcgaaag
     4381 cagtacggag agtacgagta gtgaaagtag cacaggaagc atgagtagtg agagtagcac
     4441 aggaagcacg agcagcgaaa gcagcacagg aaaagtaaat aatgaacttg atttggtacc
     4501 tatcatacca actaaggaac aaaagagaaa tgcagggagc aacctaaaaa gtgtgctaaa
     4561 acagcctgat tttgtttctc gtggaattga tcatcaagaa aaagcgaaag aaacagataa
     4621 tagaaaaagc gatttaccag aaactggtag tagaaccttg aacaagctaa ttacatggat
     4681 gggtgtgtta ctcattttga ttgtaggagc aagctatttt cgttctctct tccatcgagt
     4741 gaaataaaga ataaaagcaa cagatctaaa attgaataaa acgatagatt tttgagtgaa
     4801 tatttcattc gagagtgctg tattgcctgg cgaagttgta gctttgccag atctattttt
     4861 gtttactaac atatttgaga aacaggaaat aacaggaaca caaatggaaa ataagagcaa
     4921 gaataattga caatgcacac tgcgcatggt agtatctctg aaaaatcagt aacgaatcta
     4981 tttgtacgtt attcatgtag ctgtcggaat aagtctaaat aatagataaa aaggagtatg
     5041 tactttgttt gaagaattta ttgatatcaa tgaaaggcaa gtatatcaat ttttgaacta
     5101 ttgttatgaa agagacgaga aattatatgt ggtgaaggat atcgctttag atctaaacta
     5161 caccctggct aagatgaatt cggtgattca acaagcagaa tcgttttgcg aaaggtatcc
     5221 agaatataaa ttatcttttc tttcagaaaa caagatgata aaagtcgagt tttcttctca
     5281 gtttttactg agtaaagttt attctatact tttagaggga acgattggtt atattttact
     5341 ggattcactt tacaaaggta cttatcaatc cttagaaaat cttagtcaaa aaattatata
     5401 agtttgcgta cgattcaaag aaaattaaga gaacttaata ctattttgaa aaactatcat
     5461 ttatcttgca gcttgaaaaa aggtaatccg atagaaggag aagaataccg tatccgatac
     5521 ttttttcact tgatgtattg gcagtcattc gacgaaaatc attctgatat attatcaagt
     5581 ataaaaaata aacgtcaact attagaaaaa tttgcgaaac atgcgccata tacgcgtagt
     5641 atagatagaa agaaatggat cagcctacta agaatttcgt tgcaacgaat gaaacaaggc
     5701 cactcgatta cgtatgtccc agaagagatg aacaaatttg tgcatccatt gataacaaaa
     5761 gaagagttta cgcattacat actagagcct ttttttgaag caaacttctg gtcgatgaat
     5821 cacatcactc caacagagca agcttacctt tattttatgt ttggtgtaat gaacacctat
     5881 ttggaagaag atttgttgga tactccagat aaagtacaag aaagttgggg ctggattgaa
     5941 tcgtctattg tagaaaattt tgaaaaaaac ttcaagattt gttttacaac ttcagaaaaa
     6001 aattatctat atgtcaattt ggcaatgatc catttgtatt caagggtttt tgggacaaaa
     6061 aagaaggtgg atgcttttgg aaaatcagca gaagacagag attttcagca tatatttcca
     6121 gtgatgtatc caatcatgca acagtttttt agtggggtag ctcgcagaat tccagagctt
     6181 aatacttatt atgaaaagaa cagacggttg atttttcaat actgtatgtt agtcagggat
     6241 atttttataa aacacgaaca acctgtcata ttctatattc aatcaaagta tggtaaaaca
     6301 caggaattat gggcaaagaa aaggatatta tctatgactg aacgcccaat aaaatatagt
     6361 gcatccgctg atcagttacc tgatattgtc attagcgatt atcctatcga caaaaaggca
     6421 tatgatcaaa cgaatacaca gatattttac tggaatggac aacctacaaa aaatgattgg
     6481 gcgcgtctga aagctgaaat cataaaaatc aggaatgaga aaaatagatc catattggaa
     6541 aaattggatt tcgttaatta agaaaagcag attgtttatg ccaaaattaa gacattgcaa
     6601 aaagattatt ttctttaaaa tcgacaagat gaccagaaag caagagttcg ttgagctctt
     6661 gctttctttt agttttagaa aggaacatcc tgattttatc ttcgctaaat ccagtcaaaa
     6721 gttttgcaga ttggtcgtag ataatcggtt ttttcaataa agaaggggat gtacgaatct
     6781 caatatatag ttcactcaaa ctgagttcat ctattctgtg aacaagattt ttataactaa
     6841 tagaatgagt agagagcatt tcggtcacgc cgttgtttgt caattttagt aagtggataa
     6901 attcattttt ggttagtggt tgacgaatta agttctgttc gataaacggt atatcatgga
     6961 cgataagcca acgttttgcg cgtcttgaag acgagcagcc agaacctgta tacaatttaa
     7021 tcatcataca ttcctccaat agctaagtat ttatgaaata ataacatgaa gaaatagtcg
     7081 aaaagtgcca tttagaggtg taaaataaga aaatgttgtc acgtataatg gaactagcta
     7141 gataagaaat actattaaat caagaaaaaa gaaagaaggc acaagtatgt caaacacagc
     7201 cgacgcaata gtagtgatcg atttacaaaa aggggtatgt tttgattctt cgccgataca
     7261 cgaattagaa acagtgacag cattagtgaa taaaagaatc aaaacatacg aaacgattgg
     7321 gaaaccagtt attttcgttc aacacgaaga tgctcaatta gtgccacaaa caaaaccatg
     7381 ggagctattg tcggaattat ctattcctga gcacagttat tttgtgagaa aaacccatgc
     7441 gaattcattt tataagacta atttgagtgt tttattaact gaattggact gtcattcgat
     7501 cgaattatgt ggggcacaag cagagtattg tatagatacg actgtgaagt ttgctcatgg
     7561 attaggatac cagcttatga tgtgtagagg agcaacgaca acttatgata atccttttat
     7621 gaaagcaaag gaaacaatcg ctttttacga gaaaatttgg gataaacgat ttctgacatt
     7681 tttggagcaa taagttgttt cttcgtttaa aaaaagcaga atggatactg gtttatccat
     7741 tctgctttat tacgtaaaat gagaaaataa tcctgttcta tttttatggg ataaaccatt
     7801 tattttttgt ataaaaaatg tttgcgttta catataattc tcctagaaac ataaaaagga
     7861 gtgaatagct tgagaacaaa acaagtatta aagggagcgt tggtcatctt atttgctgta
     7921 agtacaagcg tcccgcaatg gacagtatat ggagagagca tttcttccga atcggaatct
     7981 cgggaggtag aaaccacaga aactactgat gctggaaatg aaacgaaatc gagtacttca
     8041 caaacagaaa caaatactga aacaacggtt gagacatctg ttactagcac agatcaagaa
     8101 acgaccgcta ccacagataa ccaacaaaca gaagaagcaa cagctacaaa aatgtcaaac
     8161 gacgaatcct cttctgctaa agtaagtgac aaagagaatg ggacagaaaa tgatgatatc
     8221 ggtaaaggtg aaaatttcaa tggtaaagaa tatttgaatt acttcggtaa acagatgaca
     8281 gaaatactta atggaccaac agaagacatc aagtcaaaat taatagagtt attagtcact
     8341 gagcttgctg ttaatgatta tggtgtagat aaagagatta tcaaacatct gattgctact
     8401 tatctattgt acgatatcgc ttttgcaaaa aacagtgtgt tgatgtcgat gcttggaggt
     8461 acagatgatg ggacaacgcc tacagaaaac acaggcttct atccaaatac aaaacaactt
     8521 catcaaactg tactaaacaa acaagatggc aaaatgatgg atgtatatgc atattatgtc
     8581 gatcaaggtt cagataaaac agtcatgatc catggcggat ttcgagggaa ttggaataac
     8641 gggatcgtta cagaagaata caatgatttt tataaggccg ggtataattt attatttgtt
     8701 gattccagag cgactggtaa tagcggaggc gattatgtga cctatggaca atatgagtca
     8761 gatgacgtcc tttactggat aaatcaagaa gttcgagagc ggccatctca aaagatttta
     8821 ctttatggtg gttcgatggg agcagctacg atgatgtctg tattagcgaa agatattcct
     8881 gtcaatgtca aaggaattat tgaaaattgc ggatttgcat caattgatga acaactacgt
     8941 tttacgtaca gccagacagt agcccccgca ctaccggatg ccataaaaaa tcagttagac
     9001 atcattgggg atcaagagca tgaagattta tttatgggcc ttttgaaaca atactatttt
     9061 gatcaggaga tgcatttgga tacaaaagct gctctaccta cgattggaat gtcagattca
     9121 ttgcctaaat tgattatcca tggaacagca gatgatgtag tacctgtgtc taacgcgcaa
     9181 aaattatatg agttatcagg agggtataaa gatcttttat tagtagaagg agcagggcat
     9241 ggaaaggcac aggaagttga ccatgctgcc tacacgaaac atgtaacgga ctttttgaaa
     9301 gtagtgttcc atgatcagat aaacgtaaag tatgtggatg aaaacaataa aagtctactc
     9361 aaagaccagg acgaaatcca gctttacgga gcttatggag aaaattatat gacagagcaa
     9421 aagacattcg aaggatacga attagcaaat gttgaaggac cgactgaagg gatttttaat
     9481 gagacgatac caactattat tttctattac aaaaaaatcc cagtagctcc accaaaaaag
     9541 caagatccga cagagaatgc agacaataag ggaaagaatg aacctcgaga ggatcaatca
     9601 agtgatgata cgcaaccgat tcagatgaca gtgaaagtac aaaaaaagac agatgcaaaa
     9661 aaaagaatgt tgccgaaaac tggagaaaag aaacattcgc ttctcattta ttcaggtgga
     9721 tttttatctg ttagcacgat tatcacatgg atttggcgaa gaaagagagg gtaaatgaat
     9781 gaaatggttc aagcgaatag tgattgcagt accagttatc atcgtagtta ttttagtcac
     9841 tgtatttttg attaatcaaa tcacaccaaa gccgattagc ttgcttgtta gaaaacaatt
     9901 tgacacaagt gaaaaagaac aagtatatgc ccgaccagat gatttccagc aaaaaatcga
     9961 acaaatcgat ataaaaaaag aaatatccta tccttcaaag tacaaaaata ataatatgga
    10021 tatctacaca ccgaaagtgg aaaagaaaaa attaccgatt cttttctgga tgcatggagg
    10081 cgcatatgta ggaggggata aaaatgattg tcgtgattat ttggaatatc tatgttcaga
    10141 cacgcagcaa atcatcgtaa atatagatta tgaacgatca ccggaagcaa aacatcctac
    10201 accagttatc caattgaacg aagccattca agcagctaaa aaagagataa aagatcaagc
    10261 agattggtcg aatatttcga ttggtggaaa ttcggcaggt gcacaaatta gtggagaata
    10321 tttgttagca cttcaaaatg aagaaattaa aaaagctgat catcttgatc cgactttgga
    10381 gaacaagcag attacgaagt ttatttcttt gtctggtctg ttggatcctt ctgcacttac
    10441 tcaagtaagt gataaaatct ctagctttct ttatgaaaaa tgtggatggg cttactttga
    10501 taataaggac tttgaacaat cagagaaggt caaaagttta gccttggtca gacatgcgga
    10561 tcgttggacg caaaacacat tcttaacgga tggaaataca aatacgttta cgaaacaaat
    10621 ggaagaagta acttctgtat ttgagaaagc gggggtgaaa gtcacaaaag tagattatgc
    10681 ggagaaaaat gctgttttga accatgaata tcagtttgat ttcagcaata aacaagcgca
    10741 agaaacatat caaaagttag taatgttttt caaggagtaa agtcttatga tgcaaaagag
    10801 gttgtaatct gtcacttagc tccaagtcac aaggagcaat ttcaataaac aagcttttca
    10861 tggtttatga atattgtaac ttgtgactga ggagttagag atggcaaggg gcacctttta
    10921 ttcgaaattt gggaatatca cacgattatt gtcacgatct cttttacgta aattttataa
    10981 gtcagatttg ttgttttgat cgtttaaaaa aagcaacaaa tccgaagcct gcggaggcaa
    11041 gaagggacaa aaagccgagt ggtaagcaaa agaatgctgg ttccactaat attccgttgt
    11101 tattgatata aggctgggaa caaagatgaa tagcaaataa aatcaatgca ctagcgaaaa
    11161 aaagcaaaga aatatggata gctttcataa gcagcacctc cttttttata attgtatgat
    11221 aaatagatta agaatctata aatgtgacaa gtttgttagg atgtgaataa aatgatcatc
    11281 tagcgaactt gaaacaaaga tggctaatga taagcaatta atgattcagc aatcagatag
    11341 gtacaaagtt taccatcata cgtctagacc aataatagaa aatatgggaa tataatagaa
    11401 aagatttagg atacccccaa aagaatttcc ccaaaaattc gatgtatcct aaactttttt
    11461 attttacata acaatcatat caactgtgaa ataaaattac aaatgataac ctaaaatgag
    11521 gccaaaagcc agtgttatca aggaaatact taattcacca aaattttttt taatttttta
    11581 gaaaataaga aacaaaaata ataaaaaaaa gaaaagataa attttttact actgtatact
    11641 aactttgtta tcgcatctaa caagtaactc gaataatacc aatacaacct tctccaaaga
    11701 tgcgatgaca tacgttctaa cccaccgact attgatgttc tgtaccaccc ttgcagaacc
    11761 aaaaaagcca ctaccaaata tttggtagtg gctttttttg ttttatggat ttttcgcttt
    11821 ttctgttatg gtgctattct ttgatttcag aaatagtatg tcgaacttta gcgatagaac
    11881 gacgtgattc tttttcgttg taaaacatca aaatcacata tagagagtcc aaaatgctta
    11941 gttgagaaat acgggaagct aaagcttcag atcggaattc tgtttcttca gaaatagaaa
    12001 taaaaacgac atcgccaagt ttagcaaggg aagaattagc ttggctagta ataacgattg
    12061 tttttgctcc agtttttctt acggtttcag caatatggat tgtttctttt gattgccctg
    12121 tgtgagaaat caaaacagca cagtcttttt ccgtcaataa agaagcttcc atcaattgaa
    12181 tatggtaatc cgtgctgtga gaagttgcga taggggaacg caaaaattta tgataagcgt
    12241 cagttgctac aatctctgaa ccgccaacac cgaaaaaata gacacgttta gattcattga
    12301 taatagtagc cgcttttttt agatcctttt gttgtaacaa cttttttgtg tcatttaaag
    12361 ttgaaatact agactcgaac accttttgcg ccatagtgag ctcagtatct gttttctgaa
    12421 tattttcgtg gatagaaata gcagatagat cattttcttg gatcaacatg gccattttaa
    12481 aatctttaaa tccattataa ccaagttttt ttgtaaattg aaaaaaagta gagtcagcaa
    12541 tgcccagttc acttgctaaa ttgctaatag gactatgact tactttgctt ggattttcta
    12601 aaatataatc ggcgatagcc tgttcttttg ggctgaagtc gttgtacatt gttttgattt
    12661 gtagtcttat ggagacgctc atgagaattc ctcattttca taataagatt atcatttttt
    12721 ccgttctcat taatgttaaa gatacaagga gagtaggaaa aaatcaaaca aaaaatattt
    12781 ttgtaaaatc tatttacaaa aaaatttttt tgtataatga gggtataaga aatggaggcg
    12841 ctatcatgga aattggtgta attggtttgg gaaaaatggg attgaattta gctttaaact
    12901 taaaagagca ccatcacaaa gtacaaggac tcgacatttc aagtacagct gttagtcagg
    12961 caagagaaaa tgacattcct gcttatcaag agatctctga atttctagct acttttgagc
    13021 agaaaaaaat catctggtta atgcttcctg ctggagagat aaccgaaaac atgttaagaa
    13081 aactttttcc aaaactcgga ccaggagaca ttattattga aggcggaaac tcttattata
    13141 aagattcaat ccgtcgagca gaagagtttc agaaaaatga aatcggttac ttggattgtg
    13201 ggacttctgg aggaatcgaa ggagcacgac atcaagcctg cttaatgatt ggaggagata
    13261 aagaaacttt tctatccgtg gaacaattat tcaaagatgt agcaattgaa agaggatatc
    13321 tgtatgctgg tgcatccgga agcggacact tcttgaaaat gatccataat ggaatcgaat
    13381 atggaatgat gcaagcaatc ggtgaaggat tccaacttgt acaaaaaagt gagtatgctt
    13441 ttgacttgga acaagtcgca cgtgtttgga atcatggttc ggtgattcgc ggctggctga
    13501 tggaaatcat ggaagatcag ttaaacgaac atcccaattt aagtaattat cggggaatcg
    13561 tttctgcatc aggtgaagca aaatggacgg ttgaaacagc gctagaaatg gctgttccag
    13621 ttccagtaat tgcaactagt ttgttcatga ggaatctttc acaggaagaa gatagttttt
    13681 cagcaaaagt agtttcagca ctaagaaatg ggtttggcgg acatgaaata gttgaaaagg
    13741 gtgagtaaaa tgccagatta tcatatagca atcgttaatt ccagcagttt cggaagagtc
    13801 tttccacacc acttggaaag attaaagtca gttggagacg ttcatttctt tactgttgat
    13861 caagagattc caggaaaaga actagcggag ttacttaaag gattcaatat cattattgca
    13921 agtgttacgc cattttttcg acgagatttt tttgaaaaca aagatgaact gctattgatt
    13981 tcccgacatg gtattggtta caacaatatt gatttaaaag cagcaaaaga acaccagaca
    14041 atcgtatcta tcatacctgc tttagttgaa cgaaatgctg tagcagaaaa taatataact
    14101 aatttgttgt ccatgcttcg acgcacgaca caagcacaag caagagtcaa ggacgatcga
    14161 tgggaagatc gggcggagtt cgtcggtagg acgctgttta acaaaacagt tggtgtgatt
    14221 ggtgcaggaa ataccggaag cggagtaatc gaaattttgc gtaacggttt tcgctgtgat
    14281 gttctagctt atgatcctta caaatcagat ttatacatcg aaagctttgg tgcaaaaaaa
    14341 gtagaacttc aagaattact ggaacaatca gatatcattt gtttatgtgc gaatttgaca
    14401 gaagagaact atcacatgat ttctgataaa gaagtcgatc agatgaaaga aaatgtttat
    14461 ctatctaata gtgcaagagg cgctctagtt gatgaagaag cgatgattaa tggtctgaaa
    14521 agcggaaaga tcgcaggata tgccacagat gttttagaag aagaaccggg acgtcaagat
    14581 catccgtatt tagcgtttga acaagtagtg attacgccac atatatcggc ctacacaagg
    14641 gaatgtttag aagcaatggg tgaaaaatgt gtcagagatg tcgaacagat cagtcagcac
    14701 cttcttcctg aacgttctgt ccagacaaag agcaactata taaaaggatg atgaagaaaa
    14761 tggtgaacgg tttaaaagtg aaaacaggcc ctcaatttta tttatatgaa gaaggtggta
    14821 tttcaaaagt ttctgatctc ttgaaatcat acggcgcgaa aagagtactg gtcacccacg
    14881 gaacggtatc atgggaaaag gcgctaccta aattagtatt tttgaatgac gaaacgattc
    14941 aattttttta tcatcgttat tctggagaat gtagttatgc tgaagccaga cgaatagcta
    15001 caatcatcaa aaaaatgaaa tcgatttcgt agttggcgtt ggcggaggaa aactgaccga
    15061 tctagtgggt tatagtgcca atcttgcaag aatcgatttc ggagtcatcc ctactttagc
    15121 tagtaattgt gctccatgga cacctcttgc tgtcatgtat aaggagaatg gacaagcaga
    15181 agggaaaaca gaacactttt acagacaagc tgcttttttt ataacagatc cccaattagt
    15241 gattgattcc cctgttccat atttcattgc cgggttagca gatacactag caaaatggta
    15301 tgaatctgag ctcatcttag aacaagattt tttgcaagat gaatcatttt tgaagctagc
    15361 acaagatact gcgaagatct gcaaagaaga gattttgaat cattctgcta aagcaatcca
    15421 agatatggca caaagaaaac tgacatcgga gttcaaacag ctttcagaga ttatctttgc
    15481 tgttgctggt ttagttggag gattaggaga taaatacgca agaaatgtgg cagcacatgc
    15541 tatgcatgac gctatcagta aatatattcc ggaaagccat cgttttctac atggagaaaa
    15601 agtagcgtat gggattttct atcaactggc actagaaggt cgctgggaaa aaatagacga
    15661 gttatatcct ttgtatcggg aattagaact gccggtttct ctagaacaaa tgggattatt
    15721 tccgaaagat aaacagataa tagataaaat ggctgaattt attgattcga aagagaaagt
    15781 gcatttgatt cctatagagg taacacagaa atcactgata cagtcaatga tggaactgga
    15841 aggttatatc agaaagatct gaaggaggag gacacatgga aacattaagt gtagtacaaa
    15901 gtttgttgat tgctttatgg gtagccgcgg ttatgtcccg ctggttaggt ggaggagcca
    15961 cgttgacctt acgtttttct cctttgatga ctggattagt cgtcgggttg atcatggggg
    16021 aagttgcaca agcgatgatt gttacagccg ctttgcaaat gatttatatg ggggtttttt
    16081 ctccaggagg atcaatgcca gctgaaccat ctattgcagc agctatcgca gtaccagtcg
    16141 cattattagg ggatctgtcg ccagaagcag cgattgccgt tgcggtgcca gtcggattgc
    16201 tcggaagtta cttgtatcag tttcgttttt tcatcaatac ttttttaggt aaatatacag
    16261 acaaagctgt agaagatttg aatacaaaag ctatggcccg atcaattatt ctttatccaa
    16321 cggttgcctc atttttatta ttcgttccgc ttgttttcat tgctttatat ttaggggcgc
    16381 cattgatcgc tgatgtaatc aaagctttag agggaacagt cgttatccac attcttgaag
    16441 tagtaggtgg agggttagcg gcaatcggta tcgcgacaac tgtatacgtt atcggtcgaa
    16501 aagattatct ggtctttttc ttccttgctt attttatgag tgttgttttg aaatctttag
    16561 atattacgat ggttacttat gccatttttg ggattattat cgctttgatc tttgtccagt
    16621 cgcaaaaagg gaaacaagta cagcctgcca caagcaataa caattcagca tcttttgatg
    16681 acgaagatga ctatgatgac ggattttaat ttaggaggaa tgggaaatgg ctgaaataat
    16741 ggataatcaa acaggtgctc ctgaagaaat cacgaaaaaa gatgtaacaa aagcctatct
    16801 gagatggcat tttgcaaacg aaattcctca ctcttttgaa cgttacttgg cgccatcact
    16861 actatacgga atgatgccaa tcttgaaaaa actttataaa gatgaagact ctttaaaagc
    16921 agcatataaa cggcagttac tgttcttcaa cactcaatta agctggggtg gcggtgtgat
    16981 tactggccta atgtcttcta tggaacagca aagagcagaa gaagagtatg aagaaaaaga
    17041 gatcttgatg caggatgact tgatgtataa cacgaaagcg ggattgatgg gggcactagc
    17101 aggaatcgga gatgcaatcg attcaggaac cgtccaatat atttttatcg caatcgcggt
    17161 accttgggca caacagggaa gtcctttagg cgcacttttt ccttttatct gctttgggtt
    17221 gtatcaggtt ttactagggg tatttttcgc aagacaagct ttcactatgg gccgtaatgc
    17281 tacaggccta aagcaaaaca ctggtgttca gacagcgatt gaaatgctat cagttttagg
    17341 gttgtttatg atgggggtgc ttgcgggaaa ctatgtaaaa gtagaatctt cattgaaatt
    17401 tgcgatatcc ggacgtgagt ttgttatcca ggaaattctt gatcaaatcg tgccagggat
    17461 attaccttta gctgtcgtaa tgggtgtgta cttgttctat acgaaaaaag gattgaaagt
    17521 cacacaagca ttattatggc tgactggaat attaattgtg ctagcaggaa tcggtatttt
    17581 ataaaaagaa gggaacgtga ataagatggg tgtagtcaat ttagcgcgtg tggatgagcg
    17641 tttgatccat gggcaagtaa tggtaacgtt atctcaaaaa agtggagtga attccatttt
    17701 tgttgtagac gaagttgtag caaaagataa atttatgaga gatctttaca aaaatgcagg
    17761 aagccgtaca ggacaaaaaa caattgtcat tacaccagag aaagctaaat tctattggga
    17821 tgaatatcaa tttaaagaat acaattgtat tttgatcgca aaaacagtcc aaacgattta
    17881 cgacttagta aaacacggaa tccccatgga agaattgaat attggaggga ttgctcaaaa
    17941 aaatcctgat acagatcttt tagtgacgaa atctgtttat ttaaataaat cagatgctga
    18001 aaaattgaaa gaaatgaatg aacaatatgg cgtaaagaat atttattttc aagccactcc
    18061 atctgcacct aaaacaggat taaaagatgt attgaacaag tttgatttgt cataaacaaa
    18121 tgcttagaaa aaagataaag agggcgaaaa aatgaagaag aacgagctgt ttcgtgattg
    18181 ggaatttcgt tatcgctata tttaccgtaa gcgccgtaca aaaaagagta aacagcgttt
    18241 tctttcagca ttagtatcag atatttacag tatgagaaca gatgtgacag tcattgctta
    18301 cgatacgcta gcctaccgat caaaaaatat ttatgttgga gatatcgaaa aagcagagaa
    18361 agttatctgt acttattacg atacacccgt tcatgcatta ggaagttatt tcatgtttga
    18421 ttggaaagac caaaggaaaa aaacaatcta ctctatatta ttgtccttca ttttgttgtt
    18481 cagtttaggt tggtggggaa tgatgatata taacaaaaat cctcatcacg tattcgatct
    18541 gctatccgta taaacaggta tcactgtact agcatttggg agctactttt tcttattggg
    18601 aaaagcagct cgcggatggc ctagcagaca aacttttatt cgaaatactt catccatatt
    18661 aacgatgcta gaaatgatcc gtacgattga tgatccgagt gtagcgtatg cgtttgttga
    18721 tgaaggctgt tatggagaaa agggcttaga cagcgtgaga tcgggtatga aaaaagaggc
    18781 tattcttttt tatctagact ctgttggggc agatacaccg ctacagtttt cgggaaatta
    18841 tttttcaaat aaagaacagt ggctgaaaca agttgataag ttgaaagaaa aaaacgtcaa
    18901 ttatattttt agtgcaagaa aaaagcaagc gcagttcttc tatttgacca aaacagattt
    18961 acgagggaaa acatttaatt ggcaaaatgc caatcagatt attgctcttt ttcgataagt
    19021 aaaaagtgca aaacaaggag tgagaagact aatgttggaa atcatgatcg ttacacatgg
    19081 taagttgagc gaaggactga aagatgcggc ggaagtaatt gtcgggacat cgagccatat
    19141 tgaaacaatg tgcttagagt ctggggagga catccaaaca ttcggagaga aggtcaaaga
    19201 aaaattaact atgatcaaca cagcagaacc catgctagta tttgttgatc taattagcgc
    19261 aagtccgtac aatcaagcgc tcttggcagt caatgaactg actgaagaaa agaaagcagc
    19321 cacttatgtc atagggggcg tgaatctgcc aatgttgtta gaagcaatca atcatcagat
    19381 gcttcacaca ccgatagaag aagcggtgga acaaattgtc aaacaaggaa aagataattt
    19441 aactgtttgg catgcttcag cggaagaaaa aaaattagat gaggacgatt tttagaagga
    19501 aggctgaaaa gatgaagtgg ggatttagat ggtatggtga aaaaggggat tcgatcccat
    19561 taaaatatgt tcgccaaata ccgggaataa atgggataat tggaactttg ctgactaaaa
    19621 tgcctggaga tgtttgggag atttcagaaa ttgaggagtt gaaagcatct gttgagagcc
    19681 aaggactgga actgcttgga attgaaagtg tagcgatcca cgatgcaatc aaggcaggga
    19741 cagatgaacg agattactat attgataact atatacgaac aatcaaaaac ttgtctcgat
    19801 gtggggttcg attgatttgt tatagcttca aaccaatttt tggatgggcg aaaactgatt
    19861 tgtttaatga aaacaacgat ggaagctatt ctcttttata cgatcagaaa atcgtcgatc
    19921 agatggagcc aggagaaatg tatcaattga tacacagcca gtcaaaggga ttcaaattgc
    19981 cgggttggga agaagaacgg ttgaaaaaat tcgctcagct ggaaaaactg tatgaaggaa
    20041 tgaccgaaga agaattattt gaaaatctga cttatttttt agaaaaagtg attccagtgt
    20101 gcgaaaaagc agatgtaaaa atggctatcc atccagatga tccgccatgg gaactttttg
    20161 gttttcctag agtgacgaaa aatcttggcg acttgaagaa aattctaaat gcagtagatt
    20221 ctccatataa tggactaacg ctgtgcacag gatctttagg ggcaaatccg gaaaacgatt
    20281 tagttgaaat catccatgag gtaggttcgc gcatccattt tgtccacttc agaaacgtgg
    20341 agtttttagg agaaagaaag ttcaaagaaa cggcacatcc ctctacagaa ggctcccttg
    20401 atatgtatca tattatgaaa gcgttggtgc aagaagggtt cgacggtcct atacgccctg
    20461 atcatggtag aaccgtgtgg ggtgaagtgg ctatgcctgg atatggcctg tatgatcgtg
    20521 caatgggact cacttacatg caaggtctat atgaggcgat aagtaaggaa aaaccactgg
    20581 gagagcatta tgaataaaat caagctcttc atctttgata tggatggcct tttattagaa
    20641 actggacgtt tagcttatcg tgcttatgta aaatcagcac aaaagtatga ttatgaaatg
    20701 cgtaaggaag tctattattt actaactggc caaacagaaa tggcgataag agaacaaatg
    20761 ggcattttgt acggagaaga tgttccatat atcaaatggc gagaagcaat caatcaatat
    20821 aaagaaaaaa tcgtgaaaga agataagaga gtatatacga aaaaaggagc agaagaaatt
    20881 ttatcttttg caaaagaaag aggaatccat acaatcgtgg cttcgtctaa tacacgggta
    20941 aaagtagaaa tgtatttaaa aatggaaaat ctatatgcct tgtttgatca aatcatttca
    21001 ggggatgatg taaaaaaagg aaagccggaa ccagagatct ttttgaaagc ttgttcaaaa
    21061 atgaatattc ctccaagtga agcacttgta tttgaagact cgattgcagg gatcgaagca
    21121 gcaaggcgag cgggcatttt gtcttttctc atcaaagatc atttgatagg gttgcccgat
    21181 cataatggga agcataagtt gaaagtagat gtaagtttat atgaatccaa taaagcagac
    21241 tatgaatttt atgacctgca tcaagcaaaa cgatttttag aaagtaaagg gttgtatctc
    21301 taataaagag gactattttc tagtcctctt tatttattgt cctgcacgac tgagggaaca
    21361 gatgaaaaag aagtaatttt ttattttgaa gtatctacct tatttgtagt gaacaattta
    21421 gaacaaacac aaaacgcatc tactgttatc taccagtaga tgcgtttaaa gagaagaacg
    21481 agaatcgtcc atatgagggt ttc
//
LOCUS       DAFBVQ010000047        20938 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.049, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000047 DAFBVQ010000000
VERSION     DAFBVQ010000047.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20938)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20938)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20938
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.049"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            165..359
                     /locus_tag="LLC22_001945"
     CDS             165..359
                     /locus_tag="LLC22_001945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292375.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435221.1"
                     /translation="MYYVEVKTKGVKNKQYVKGISNEYPLLGSWKEAAPFSKPCAIKI
                     KNELEKELTCGKAVVDIIEK"
     gene            628..926
                     /locus_tag="LLC22_001946"
                     /pseudo
     CDS             628..926
                     /locus_tag="LLC22_001946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323300.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(1023..1457)
                     /locus_tag="LLC22_001947"
     CDS             complement(1023..1457)
                     /locus_tag="LLC22_001947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5435222.1"
                     /translation="MNIDSLMIDEISELYKSVGWTNYTKDTARLARAFEQSESLIKRN
                     GEGKIIGIVRWITDFATIAFIQDILIHPRYQRQGIGKVLLNEALEKITSYGPVQIELL
                     TDDTEKTKKFYESVGFVQVKEMGGISYVIDTRRKKVLFGNDK"
     gene            complement(1689..2399)
                     /locus_tag="LLC22_001948"
     CDS             complement(1689..2399)
                     /locus_tag="LLC22_001948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629987.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 4-epimerase"
                     /protein_id="HBK5435223.1"
                     /translation="MSCEEKIAAMKQRVLEANLALPRYGLVKLTWGNVSEVDRELGVI
                     VIKPSGVRYECMQADQMVVTDLSGNIIEEDSLKPSSDLPTHVVLYQTFEDITAITHTH
                     STHSVMWAQAGRDLPAYGTTHADAFYGKVPCTRQLTKEEVREAYEVHTGNVIVETFKE
                     RKLDPNEVPGVLVYGHGPFTWGDSPMKAVENSLILDEICLMAKENELINPNICEIPQY
                     LLDKHYFRKHGKYAYYGQ"
     gene            complement(2389..3249)
                     /locus_tag="LLC22_001949"
     CDS             complement(2389..3249)
                     /locus_tag="LLC22_001949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342714.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ribulose-5-phosphate 3-epimerase"
                     /protein_id="HBK5435224.1"
                     /translation="MAQIGIYEKALPKDISWKERFSLVKEMDFDFIEMSIDETDERLA
                     RLDWSEEKIAELREEMFSSGVRIHSICLSAHRRFPFGSADPEKKKAAKQLMKKAIHLA
                     HNLSVKVIQIAGYDVYYEEKSMNSREDFIEGIKESVKEASKYGIILSVEIMDDPFMNS
                     ISKFLEIKEQIHSPFLQVYPDLGNLSAWPENNPARELEKGIDYITAIHLKDTYPVTKE
                     YSGQFRDVPFGSGCVDFLGLLRHLKRLDYDGTFLIEMWSEKSQDFRREIQQAKDYLSS
                     KLKEAGYDVL"
     gene            complement(3254..3892)
                     /locus_tag="LLC22_001950"
     CDS             complement(3254..3892)
                     /locus_tag="LLC22_001950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-keto-L-gulonate-6-phosphate decarboxylase
                     UlaD"
                     /protein_id="HBK5435225.1"
                     /translation="MSRPNLQIALDHNDLEHALGDVMKVGDVVDIIEVGTILCLQEGQ
                     KAIRCIRSMFPDKKLVADTKCADAGGTVASNVAKAGADWMTVICCATIPTMEAAQKEI
                     GELQVELYGNWTFEQAMDWHNIGIRQVIYHQSRDALLSGETWGEKDLSKIKKLIELGF
                     NVSVTGGLNPHTLHLFEGIDVYTFITGRGITAANDPMKAAQNFKDEIIRIWG"
     gene            complement(3907..4206)
                     /locus_tag="LLC22_001951"
     CDS             complement(3907..4206)
                     /locus_tag="LLC22_001951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5435226.1"
                     /translation="MRILVSCANGSGTSLMMMRSVEKAMKELNVPITKIHHCAISEGK
                     SSAGQYDVVFTPVNFLNMFTQAEKKGVTVIGIKNVMSVKEISEKFAETKWYQKNK"
     gene            complement(4249..5733)
                     /locus_tag="LLC22_001952"
     CDS             complement(4249..5733)
                     /locus_tag="LLC22_001952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS ascorbate transporter subunit IIC"
                     /protein_id="HBK5435227.1"
                     /translation="MGEFLLSIWTYFATNILTQPAYLIGFIVLLGYILLKRPLHECIA
                     GFLKATVGYFILTVGSGGLVNNFRPILVGLKERFNLDAMVTDPYFGQNAVDAGLMETF
                     GRTFGDVMILLLIAFVLNILLVRFQKYTKLRSVFTTGNVQVQQAATAFWILLFCFPDL
                     GRIQALIFMGLILGCYWTVASNLTVGITQELTEGAGFAVAHQQMFGIFIFAKLAEWMK
                     KRDEKKNRSIKQDKKIEDIKLPGFLSIFNENMVATSLLMLFFFGIILIVLGKDYLIQA
                     QFMQEGQSFLFYIMTTSLNFAVYLAILQLGVRTFVDELTQSFQGISNTILPGAVPGID
                     VAATFGFGSPNAVTIGFLFGALGQFLMIGLLILLKSPTIVIAGFIPLFFDNAVIAVYA
                     NNRGGFKAACLFPFLSGIIQVGGSALFATWIGMSTYGGYIGMFDWATAWPLFTVIMKV
                     LGYAGIAVVVIGLLAIPQLQYRKNPDGYFLIVEDYDTYAEKQRV"
     gene            complement(5753..6214)
                     /locus_tag="LLC22_001953"
     CDS             complement(5753..6214)
                     /locus_tag="LLC22_001953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002372910.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5435228.1"
                     /translation="MLKYFFDHQLIHYPDKEITDWREAIAESCLVLIDKEIIDETYVE
                     EIIHCVEKYGPYIVIAPQVAMPHSSEKSDGVFGTAISFTKLKQPIRFESEGENEEKTA
                     SLFFTLAAKDPEEHLENIQKLSELLMTDGLVERLISTNSIDDYQVVMAEYN"
     gene            complement(6232..7299)
                     /gene="ulaG"
                     /locus_tag="LLC22_001954"
     CDS             complement(6232..7299)
                     /gene="ulaG"
                     /locus_tag="LLC22_001954"
                     /EC_number="3.1.1.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323295.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="L-ascorbate 6-phosphate lactonase"
                     /protein_id="HBK5435229.1"
                     /translation="MSKTVNEVTKEKWLVETFPEWGTYLNEEIETEVVDPGTFAMWWL
                     GCTGIWLKSHEGTNILCDLWCGTGKRSHGNGMMKKGHQMMRMSGVQNMQPNLRTQPFV
                     IDPFAIKNVDALIVTHIHSDHLDIHTAAAVHQNCPEATFIGPKEVVRTWQKWGIPEEK
                     TITVKPGDAVKIKDINVVALEAFDRTALVTCEDPEEVLKGKMPQEMDQIAVNYLFETS
                     GGNLYHAGDSHYSNLFAKHGNEHKIDVCLGAYGENPRGITDKVTSVDMLRMAESLNAK
                     VVIPVHYDIWSNFMADPKEITEIWKFKKDRLKYGFKPYIWQVGGKFIYPTNKDDLEFN
                     FYRGFEDVFSIENDTPFPSFL"
     gene            7517..8287
                     /locus_tag="LLC22_001955"
     CDS             7517..8287
                     /locus_tag="LLC22_001955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5435230.1"
                     /translation="MKNSLVNIEKRQKEILELLQQTEQLSTFELAESLDVSISTIRRD
                     LNLLEEKNEIIRNYGYCSYNYKNQTDFDQSGPERIKQAIAREASKYINDYDTLFINSS
                     STALKTLDFLQSNHLTVITNNVKINYSPHKDNCSYILTGGEMRFPKEALVGDIALNTI
                     SSVNADICIIGCSGVDVVHGVTTKILNESTINEMMVNKTIKCKILVADHRKIGLTSKF
                     KIADISVFDYLITDKFCSEKVLEEIRNTGIKTIQVDSF"
     gene            complement(8560..9387)
                     /locus_tag="LLC22_001956"
     CDS             complement(8560..9387)
                     /locus_tag="LLC22_001956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5435231.1"
                     /translation="MIKVDGALLKEYRKKKGLTQVQLAEGICEQATVSNIENKNMSPG
                     INILSALCKKLNVEISDILVETEEDKIRKKINEIQSLNSVSKYQESYKILQTIDQEKV
                     SNSDLLNQILFYQGLLDHLYAKKPDAALFYFNQVLEQTTETDIHHLQAAANVAMIYLS
                     KGELDFAKVYVERTLKILSETDFDNLMVCIVYYDIATYYRKIEDYDKAIQLCEKGIEY
                     NKKHKSTYALEYLLYEIASCHKQLGEDDYLERYMDAKKIARFNGNDYAVKVIENDLK"
     gene            9955..11190
                     /locus_tag="LLC22_001957"
     CDS             9955..11190
                     /locus_tag="LLC22_001957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336948.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBK5435232.1"
                     /translation="MKTILFAPAVFNLAETTRMIEVAKAMKDRYYCVFFGFSKTFAPL
                     ITESGFEYHLLAPILTKKQEEQIIKFDQLRTLKNPFTKEMVASRITSEQSLIAKFEPR
                     LIVTGSNVTIFLSARNKKIPLVYVKPYALSEPFFQSEHALMPHELRFFGPLSNPLWHW
                     TKKRIVNTRWIPNAFKHAAQKEMLPLPKTSLQMMDADLNLITTPKLFLEEEQLPENYR
                     IVGPIFAKLSTSLPEEVLTFIQRKQQERKRIIYFAMGSSGNPRMLRKILFFLQKQPDL
                     AVIAPIDYLLDDIQSDSEDLLITEYLSSHLLHEFIDFSFIHGGEGTVQTACESGKPFI
                     GVGMQFEQSCNIDYCVKYGNAIALTKPVTERKLQIALREVSSPKIRQQARTLQAVFPI
                     NGPQQAIQEIETFLSNHPI"
     gene            complement(12189..12449)
                     /locus_tag="LLC22_001958"
     CDS             complement(12189..12449)
                     /locus_tag="LLC22_001958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327982.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase"
                     /protein_id="HBK5435233.1"
                     /translation="MYWLILFFVFIFLLTASHLILNMLATYHIQINRWIWALASFLIV
                     ILPKIIVPHMNVLFSWGTYVLCGIFAINFMIEQHRWFVTSKL"
     gene            complement(12476..13777)
                     /locus_tag="LLC22_001959"
     CDS             complement(12476..13777)
                     /locus_tag="LLC22_001959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5435234.1"
                     /translation="MEKLMKWVEEKLVPPMAKIGTQRHLLAIRNGVVSTLSLILIGTF
                     FMVFINLPFPGWNEFIAPYSATIVLPFRMTMGLMAIYATFVMGSDLAKSYGLDSVTGG
                     ILSLGTFFMLQVPVNVLTPEEAPLGWVLPMSSLGASGMFAGILSMIFAVEVYRFFKNR
                     NITIKMPEQVPPAVARSFEALIPGAVILTITWLIRSVAGFDVNAALLSLFEPLTNILG
                     NNLLGVLLPMFLIHLLWSFGIHGMSIVGAVVRPMWLIMLDENAKALADGTAATQLPYI
                     APEQFYQWTVTIGGAGATIVVSVLFIFFCKSKFLKEVGRFSIIPGIFNINEPIIFGAP
                     MMLNPYMFIPFNLVPLVLTIISYFAVKLEMVNRFTVLPTWTLPAPIGGYLSAGNDWRV
                     VILIMINTLIAFIIYYPFVKAYDKKMLSDEQSRGENEVQTV"
     gene            complement(14069..14527)
                     /locus_tag="LLC22_001960"
     CDS             complement(14069..14527)
                     /locus_tag="LLC22_001960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5435235.1"
                     /translation="MHFFKTRNILKAVASGQIIPLTAVKDEVFSSKMIGVGYAITNHD
                     GYIHAPVKGIIDNIFPTRHAITIESESGRKILIHMGLDTVELEGSPFQIRVESNQEVK
                     EGTLLAIIDLKKLEQAQKDTVIIVVSPGIFEGNLLKQNQEVKIKDSCFEF"
     gene            complement(14540..15871)
                     /locus_tag="LLC22_001961"
     CDS             complement(14540..15871)
                     /locus_tag="LLC22_001961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361883.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="maltose-6'-phosphate glucosidase"
                     /protein_id="HBK5435236.1"
                     /translation="MMMKKQIITIAGGGSTYTPGIVQAILNNEKRLPLSEIRLYDIDE
                     ERNMDMYLIVKFMLKRKGFSNIRIRATDDPKLAFTGRDFVFSQIRVGGLEMREKDEKI
                     PLKHGLVGQETCGLGGFAYGMRSIKGLLEIVDHIQDYAPKAWILNYTNPESIVSEAVR
                     RKYPNVKMINACDMTISIEETIAVNYGYDRKNWIVTYYGLNHFGWYTSIYDKELQREI
                     MPEIIEKLITKEMQVADFNIGDKTWQKTFQMMSVITKNFPSNIPNNYLEYYLYPDMVV
                     EHTDKEYTRANMVMDGREKNTKEMADKIRRGIVEEVLNFNFGEHGQYIVDIAISLLND
                     DRRRFMLIVPNQGAIPNLRSDAVVEIPAYVGATGVEPITLRKPISDFHKGLMEAQVAV
                     EKLLVDAYFEGSYQKALQAFTLNQTVPNARVAKKILDEMIKVNKKYWPALK"
     gene            complement(15882..17324)
                     /locus_tag="LLC22_001962"
     CDS             complement(15882..17324)
                     /locus_tag="LLC22_001962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321325.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5435237.1"
                     /translation="MRIFNRGGIKMNVKSNVQKLGRAMLLPVAAMPLAGLIMRLSADD
                     MLNIPVIGAAGNAVFGNLDILFAIGVAIGFVKNKDKGIPALTGFLAIATLKKGLEIMD
                     PEVNMGIFGGIISGLVAAWTYNRFKEQKLPVVFSYFAGEKFPLTMVMILQTIAAVFLG
                     FIWPLIQIGIDNFAKLLVDMGALGVGIFMFLNRLLIPFGLHHVLNTYIYYDLGSYTSP
                     SKEVFRGEMTRFINGDPQAGLFLSVFFVVMMFGIPAICLAIYKAAYKENKEMVKGIMG
                     SGAGTSFIANITEPVEFSFMFLSPMLYVIHALFAGLGGIVCYLFNIRIGFTFGACIVD
                     YLINFRIATNAILILPIGIFFFALYYVTFYYLINKRNIQTLGREAKAEFGNEVTLEET
                     ELGLASKNYEYMATKMLQAFGGKANILDVYSCNTRLRVEVVDPTMVEEQRIKQLGISG
                     IIKPTEKNYQIIIGLEVTYVMAEFNKLLEE"
     gene            complement(17311..18075)
                     /locus_tag="LLC22_001963"
     CDS             complement(17311..18075)
                     /locus_tag="LLC22_001963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318971.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate deacetylase"
                     /protein_id="HBK5435238.1"
                     /translation="MGKVIFNSDDFGYSHGVNYGIMDAYQRGILTSTTLMANMPGFEH
                     AVKLRKEMPRLGVGVHLTLTCGKPLLKTVDTLIESGEFRSLSYYQHPFNIDKDQLYQE
                     WNAQIQKIYHAGIIPTHLDSHHHTHTLDENQEVVVTLAKKYDLPVRSNFERKDEVRHV
                     DYFEPCFDVVGETDEKKRQINTSVEEYLASLLMILREDKTIEVMCHAAYLDQELLNGS
                     SFVYPRTHQVEFLIHSAFAQKVKNDPLIELVTYEDI"
     gene            complement(18179..19054)
                     /locus_tag="LLC22_001964"
     CDS             complement(18179..19054)
                     /locus_tag="LLC22_001964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5435239.1"
                     /translation="MKESASCFVLSYRGGELTVYVMKKLNHNAVLVDDDGIEKIAMGK
                     GIGFSAKVSKPFDVEDADKLFVLDSKEKIKRFSEIVSQIPIEFMDFAEEVIELITARI
                     SSPLDSNIYITLTDHIYFAIQRKREDRDVTAIMLPEMRFLYPNEYDIAVEVVERINHR
                     YQTELGSNEVGFITMHIINAELGEPNSLKSLKIVEMTTTILSHLEKSYSNVYDKESLT
                     YHRLMVHIKFLVKRLIYQEETPVENIGFFTETFKHSKAYCTALKIKDIIEQQFQLAIQ
                     ENEIIYLAIHLARIY"
     gene            complement(19309..19393)
                     /locus_tag="LLC22_001965"
     tRNA            complement(19309..19393)
                     /locus_tag="LLC22_001965"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19357..19359),aa:Leu,seq:caa)
     gene            complement(19411..19482)
                     /locus_tag="LLC22_001966"
     tRNA            complement(19411..19482)
                     /locus_tag="LLC22_001966"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19448..19450),aa:Gln,seq:ttg)
     gene            complement(19492..19564)
                     /locus_tag="LLC22_001967"
     tRNA            complement(19492..19564)
                     /locus_tag="LLC22_001967"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19529..19531),aa:His,seq:gtg)
     gene            complement(19626..19710)
                     /locus_tag="LLC22_001968"
     tRNA            complement(19626..19710)
                     /locus_tag="LLC22_001968"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19674..19676),aa:Leu,seq:caa)
     gene            complement(19731..19801)
                     /locus_tag="LLC22_001969"
     tRNA            complement(19731..19801)
                     /locus_tag="LLC22_001969"
                     /product="tRNA-Cys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19767..19769),aa:Cys,seq:gca)
     gene            complement(19847..19918)
                     /locus_tag="LLC22_001970"
     tRNA            complement(19847..19918)
                     /locus_tag="LLC22_001970"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19884..19886),aa:Gln,seq:ttg)
     gene            complement(19930..20002)
                     /locus_tag="LLC22_001971"
     tRNA            complement(19930..20002)
                     /locus_tag="LLC22_001971"
                     /product="tRNA-His"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(19967..19969),aa:His,seq:gtg)
     gene            complement(20005..20078)
                     /locus_tag="LLC22_001972"
     tRNA            complement(20005..20078)
                     /locus_tag="LLC22_001972"
                     /product="tRNA-Trp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20044..20046),aa:Trp,seq:cca)
     gene            complement(20085..20165)
                     /locus_tag="LLC22_001973"
     tRNA            complement(20085..20165)
                     /locus_tag="LLC22_001973"
                     /product="tRNA-Tyr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20129..20131),aa:Tyr,seq:gta)
     gene            complement(20167..20242)
                     /locus_tag="LLC22_001974"
     tRNA            complement(20167..20242)
                     /locus_tag="LLC22_001974"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20207..20209),aa:Phe,seq:gaa)
     gene            complement(20278..20350)
                     /locus_tag="LLC22_001975"
     tRNA            complement(20278..20350)
                     /locus_tag="LLC22_001975"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20315..20317),aa:Asp,seq:gtc)
     gene            complement(20360..20432)
                     /locus_tag="LLC22_001976"
     tRNA            complement(20360..20432)
                     /locus_tag="LLC22_001976"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20397..20399),aa:Val,seq:tac)
     gene            complement(20448..20519)
                     /locus_tag="LLC22_001977"
     tRNA            complement(20448..20519)
                     /locus_tag="LLC22_001977"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20484..20486),aa:Glu,seq:ttc)
     gene            complement(20534..20623)
                     /locus_tag="LLC22_001978"
     tRNA            complement(20534..20623)
                     /locus_tag="LLC22_001978"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20587..20589),aa:Ser,seq:gga)
     gene            complement(20663..20736)
                     /locus_tag="LLC22_001979"
     tRNA            complement(20663..20736)
                     /locus_tag="LLC22_001979"
                     /product="tRNA-Asn"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(20700..20702),aa:Asn,seq:gtt)
     gene            complement(20746..20861)
                     /gene="rrf"
                     /locus_tag="LLC22_001980"
     rRNA            complement(20746..20861)
                     /gene="rrf"
                     /locus_tag="LLC22_001980"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT         6599 a         4392 c         3331 g         6616 t
ORIGIN      
        1 gaacaatagc cttttattat atatattatt caaattagtt atatcgagtg aaaaaaactt
       61 tcaaattgat tctttttatt tatcataaag atatagatac ataatcattt tcacttacat
      121 atatttgaat attaactaaa aacagcaaga aagaagagga tcaaatgtat tatgtagaag
      181 taaaaacaaa aggcgtcaaa aacaaacaat atgtgaaagg tatcagtaac gaatatcctt
      241 tacttggttc atggaaagaa gctgctcctt tttccaaacc atgtgccata aaaataaaga
      301 acgagctaga aaaagaactg acttgtggta aagctgttgt agatatcatc gaaaagtaaa
      361 tccaatgtat agaaaggaag atcacacatg aaaagcgacg tacaaattgc taagattata
      421 gaattagaag aagaagacgc agtgttgaca attgaaaaaa aataaatgtt tgtataccat
      481 atgattattt caatatgtat cctggaattg gagatctcgt agagctatat caagatgaat
      541 caaatatact tgtcattcat catgaaatat agagacttat aaaattgttt atttttataa
      601 tgtatcagta tagaaaggaa ataaaacatg gattatactg ttgaatttga cagtgaacta
      661 cttaagcaat ttccacaaga agaacatttc atgtataaag aagcaatttc ccacaaagtg
      721 acagagtatt tggagcataa tttttttcgt ataaagccag tgcgtactcg ttcggcaaaa
      781 ggaatatacg agatgaaagt caaaattaat aaaaaaaatt atcgcatagc atttgcttta
      841 aaaaaaatca tgtgttcatt ttttatatta gttcgaattt gcaaaaaatt gtatttgata
      901 aagaggtgag taaaaaaata aaatagctga gcattggagg atagattgag tgatactaag
      961 tctatcctct tgtttttcta aagaactaag ctagaatttt ttcttttgta cgttattata
     1021 tgttatttgt cattaccaaa aagcaccttt tttcttctag tatctatgac ataagaaata
     1081 ccacccattt cctttacttg aacaaatcct actgattcat aaaatttttt tgttttctca
     1141 gtatcatctg tcaataattc gatttggact ggtccataac tagtgatctt ctccaaagct
     1201 tcattcaaaa gcactttgcc tattccttgg cgctgatacc tcggatgaat gaggatatct
     1261 tgaataaatg cgatcgtcgc aaaatcagtg atccaacgaa cgattccgat aatcttccct
     1321 tccccattac gctttatcag agattcagat tgttcaaatg ctctagctaa ccttgcagtg
     1381 tcttttgtgt aattcgtcca accaacgctc ttatataatt cagaaatctc atcgatcata
     1441 agggaatcaa tattcatttt tttcttcctt tcttatacaa ttctccctct aataatacag
     1501 ttctttgact atttaatcta tcacatataa ctctcctgta aagattctct cgattcctta
     1561 aaattcctct ttccttttag aatgcatact ttttgataaa taaaaaggtt gtgataaatt
     1621 ttcttcacaa cctctgtttc tctctatcaa gtgttatctt ttaattttct acccttaccc
     1681 tagcatctct attgcccgta gtatgcatac tttccatgtt tgcgaaaata atgtttatct
     1741 agtaaatatt gcgggatttc acatatattg gggttgatca gctcgttttc tttggccatc
     1801 agacaaattt catctaagat caaactgttt tctactgctt tcataggtga atccccccat
     1861 gtgaacggtc catgtccata gacaagtact ccagggactt cgtttggatc taattttctt
     1921 tccttaaacg tctcgacaat cacattccct gtatgaactt cgtaagcttc tcttacttct
     1981 tctttcgtta attggcgtgt acaaggaacc ttaccataaa aagcatcagc atgagtcgtg
     2041 ccataagctg gcaaatcgcg tcctgcttgc gcccacatga cggagtgcgt ggaatgagta
     2101 tgagtaatag cagttatatc ttcaaaagtt tgatacaaaa caacatgtgt ggggagatct
     2161 gaagatggtt ttaagctatc ttcttctatt atatttcccg acaaatctgt taccaccatt
     2221 tgatctgctt gcatgcattc atatctgaca ccgcttggct taatgacgat gactcctagc
     2281 tcacggtcca cttcactcac attgccccaa gtcaatttga ctaatccgta tcgcggcaat
     2341 gccagatttg cttcaaggac acgttgcttc attgctgcaa ttttttcttc acaagacatc
     2401 atagccagcc tccttcaatt tagaacttaa gtagtctttt gcctgctgga tttctcttcg
     2461 aaagtcttgg cttttttcac tccacatttc aatcagaaat gttccatcat aatctagacg
     2521 tttcaaatgt cttaataatc caagaaaatc aacacaaccg ctaccaaaag gaacatcacg
     2581 aaactggcct gaatattctt ttgttacagg gtaagtatct tttaagtgga tagcagtgat
     2641 ataatcgatc cctttctcaa gttctcgagc cggattattt tccggccatg cggacaaatt
     2701 gcctaggtct ggatatactt gtagaaaagg tgaatgaatc tgttctttga tttctaaaaa
     2761 ttttgaaatg gagttcataa atggatcatc catgatttcc acggaaagaa tgatgccata
     2821 tttagaagct tcctttacgc tttcttttat tccttcgata aagtcttctc tggaattcat
     2881 tgatttctct tcataataaa catcgtatcc agctatttgg attactttga cgcttagatt
     2941 atgcgccaaa tggattgctt ttttcattag ttgtttcgct gcttttttct tttctggatc
     3001 agcagaacca aacggaaatc gccgatgcgc acttaaacaa atcgaatgga tacgtacacc
     3061 ggagctgaac atctcttctc tcagctcagc tatcttttct tcagaccaat ctaatcgtgc
     3121 taaccgctca tccgtctcat caatcgacat ctcgataaaa tcgaagtcca tttcttttac
     3181 aagggaaaaa cgttctttcc atgaaatatc tttgggtaac gctttttcat aaatcccaat
     3241 ttgagccatt tccttacccc cagatacgaa tgatctcatc tttgaagttt tgtgcggcct
     3301 tcatcggatc atttgctgct gtaataccac gaccagtgat aaaggtatac acatcgatcc
     3361 cttcaaataa gtgtaatgtg tgtggattta atccaccagt tacagaaaca ttaaagccta
     3421 gttcaatcag ttttttgatc ttcgataaat ctttttcacc ccaagtttca ccagataaca
     3481 gcgcatcacg gctttgatgg tagattacct gccggatacc gatgttatgc caatccatgg
     3541 cttgttcaaa agtccaattg ccgtagagtt ctacttgcaa ttcacctatt tctttttgtg
     3601 ctgcctccat agttggaatc gttgcacaac aaatgactgt catccagtct gctcctgctt
     3661 ttgcaacatt actcgccact gttcctccag cgtctgcaca tttcgtatca gcgactagtt
     3721 ttttatctgg gaacatactg cgaatacagc gaatcgcttt ttgtccttcc tgtaagcaaa
     3781 gaattgtgcc cacttcaata atatctacta catcaccaac tttcataaca tctcctaatg
     3841 catgttctaa gtcattgtga tctaacgcaa tttgcaaatt cggcctgctc atcttagttc
     3901 cttcctttac ttgttttttt ggtaccactt tgtttcagca aatttttcac tgatttcttt
     3961 gactgacatc acatttttga taccgataac tgtaactcct tttttctctg cctgagtaaa
     4021 catattcaaa aaattgactg gcgtaaaaac tacatcgtat tggccagctg aactttttcc
     4081 ctctgaaatg gcacaatgat ggattttggt aattggtacg tttagttctt tcattgcttt
     4141 ttccacactt ctcatcatca tcaagcttgt tcctgatcca tttgcacacg atactaaaat
     4201 tctcatctta atccctccat tatgagtgtt gtctaatcag attttctttt atactctctg
     4261 cttttctgca tatgtgtcat agtcttctac aatcaaaaaa taaccatcag gatttttccg
     4321 atattgtaac tgcggaatag ccaataaacc aatgacaact acggcaattc cagcataacc
     4381 taggactttc atgattactg taaacaatgg ccaagctgtt gcccagtcga acatcccgat
     4441 ataaccaccg tatgttgaca tcccaatcca tgtagcgaat aatgctgaac cgcctacttg
     4501 tatgattcct gaaagaaacg ggaacaggca agcggctttg aatccacctc ggttattggc
     4561 ataaactgct ataacggcat tatcaaagaa caacggaatg aaaccggcta tgacgatcgt
     4621 tggtgatttc aataaaatca gtaaaccaat catcaaaaac tgtcccaaag caccaaacaa
     4681 gaacccaatc gttaccgcat ttggcgaacc aaagccaaaa gtagcagcta cgtcaattcc
     4741 tggaacagct cctggtaaaa tcgtgtttga gattccttgg aaagattgag ttagttcatc
     4801 gacgaatgtc cgaacaccta attgcaagat cgccagatat accgcaaaat ttaaagaagt
     4861 cgtcataatg tagaataaga aactctgccc ttcttgcatg aattgcgctt gaatcaaata
     4921 atctttgcct agtacaatca gaatgatccc aaagaaaaat agcatgagta acgaagtagc
     4981 aaccatattc tcattgaaaa tcgacaagaa tcctggtaat ttgatatctt caattttttt
     5041 gtcttgcttg attgatctat ttttcttttc atcccgcttt ttcatccact cagctaattt
     5101 tgcaaatata aagattccga acatttgctg atgtgccact gcaaatccgg caccttctgt
     5161 caattcctgc gtgattccta ctgttaagtt agaagctact gtccaataac aacctaaaat
     5221 cagtcccata aaaatcaatg cttgtatcct acctagatca ggaaagcaaa acagtaaaat
     5281 ccaaaaagcg gtagctgctt gttgaacctg aacgtttccg gtagtgaaaa cggaacgcag
     5341 tttcgtatat ttctgaaaac ggactaataa gatatttaaa acaaatgcaa tcagtaataa
     5401 aatcatcaca tctccaaagg tacggccaaa tgtctccatt aatccagcat ccacagcatt
     5461 ttgtccaaaa taaggatctg taaccatggc atccaaattg aaccgttcct ttagtccaac
     5521 caagattggc cgaaaattat tgaccaaacc accagagcca acagtcaaaa taaagtaacc
     5581 gaccgttgcc tttaagaatc cagcgatgca ttcatgaagc gggcgtttca gcaaaatata
     5641 gcctaataac acgataaaac caatcaggta tgctggctgc gtcaagatat ttgttgcaaa
     5701 atacgtccaa atgcttaaca aaaattcccc catctttttt ctcctctatc aattaattat
     5761 attctgccat cacaacttgg taatcatcga tggagttcgt agagatgaga cgctcaacca
     5821 atccatctgt cattaataat tcggataatt tttggatatt ttctagatgt tcttctggat
     5881 cttttgctgc gagtgtaaaa aacaaactag ccgttttctc ctcattctcc ccttcacttt
     5941 caaaacggat tggctgtttc aacttggtaa atgaaatagc tgttccaaaa acaccatcac
     6001 ttttttctga agaatgcggc attgctactt gaggtgcgat cacaatataa ggaccgtatt
     6061 tttctacaca atggatgatc tcctccacat acgtttcatc aataatttcc ttatcgatca
     6121 atacaagaca gctttcggcg atagcttcac gccaatccgt gatttcttta tctgggtaat
     6181 gaatcaattg atggtcaaaa aagtatttca gcaagaaact ccccttcttt cttataaaaa
     6241 cgacggaaac ggtgtatcat tttcaatcga gaagacatct tcaaatcctc gataaaaatt
     6301 aaactcaaga tcatctttgt ttgtcggata gatgaatttc ccgcctactt gccagatata
     6361 aggtttaaat ccatacttca ggcgatcctt tttgaatttc caaatttcag tgatctcttt
     6421 tggatcagcc ataaaattag accaaatatc gtagtggaca ggaatcacta cttttgcatt
     6481 caatgactcc gccatgcgca gcatatcaac agaagtaact ttgtctgtta tccctcgtgg
     6541 gttttcacca taggccccta aacagacatc gattttgtgt tcattaccat gtttggcaaa
     6601 taaattggag taatgtgaat ctcctgcatg ataaagattc cctcctgatg tttcgaataa
     6661 atagtttact gcaatttgat ccatctcctg aggcattttt ccttttaata cctcttctgg
     6721 atcttcacaa gtgaccaacg ctgtccgatc aaacgcttct aaagctacta cattgatgtc
     6781 tttgattttg actgcatcac ctggctttac tgtaatcgtt ttttcttcag gaattcccca
     6841 tttttgccac gtgcgaacca cttcttttgg cccaatgaat gttgcttcag gacaattttg
     6901 atgaactgct gcggctgtat ggatatctag atgatcggaa tggatatgtg taacgattaa
     6961 agcgtctaca ttttttatcg caaaaggatc gattacgaaa ggctgagtac gtaaattagg
     7021 ctgcatattt tgaacgccac tcatacgcat catctgatgg ccttttttca tcatgccatt
     7081 cccatgacta cgttttcccg tcccacacca tagatcacat aaaatattcg ttccttcatg
     7141 acttttcagc caaattcccg tacagcccag ccaccacata gcaaaagttc caggatccac
     7201 tacttctgtt tcgatttctt cattcaagta tgtgccccac tcaggaaatg tttctactaa
     7261 ccacttttct tttgttactt cattgacagt tttactcatt tgcttgctcc ccccatatcg
     7321 ttgttccaac ttacaagtaa atattaatgt gtatcagcat ccatgaaaac ccttttatat
     7381 gaccgtttgt tttttatatg attttctttc agtaatcaat gattgtttca gtataataaa
     7441 gacagatatg aatgtttaaa tgaacaacta gtcaaataaa tccatggatc aagatgtccc
     7501 tcaggaggca aaagtcatga aaaactcact tgtcaatatt gaaaaacgtc aaaaagaaat
     7561 tttggaactg cttcagcaga ctgaacaact atcaactttc gaattagctg aatcccttga
     7621 tgtatctatt agtacgatac gaagagattt aaatttatta gaagaaaaaa acgagatcat
     7681 acgcaattac ggttattgtt cttataatta caaaaaccag actgattttg atcaatctgg
     7741 tcctgaaagg attaaacaag cgattgccag agaagctagt aaatacatta acgattatga
     7801 tacgctgttt atcaattcta gctcgactgc gttgaaaaca ctggattttc ttcaatctaa
     7861 ccatttgaca gtcattacaa acaacgtgaa aatcaattac tctccgcaca aagataattg
     7921 tagttatatt ttaactggtg gagagatgcg ctttccaaaa gaagcactag tgggcgacat
     7981 cgcattaaat acgatttctt cagtcaatgc agacatttgt atcattggct gtagcggagt
     8041 cgatgtagta catggggtca caacaaagat attaaatgaa tcaacgatca acgaaatgat
     8101 ggtcaacaag acaatcaaat gtaagatttt agtcgctgat catcgaaaaa tcggactgac
     8161 atcaaagttc aagattgctg atatttcagt ctttgattat ttgatcactg ataaattttg
     8221 ttctgaaaaa gtattagagg agatcagaaa tacggggata aaaaccattc aagtagattc
     8281 attttaagaa ccaggacgta aatatgtaaa taggattatc aaaaaaatga ataacaaatt
     8341 tatcgataaa tgaaaaacac gctacgctca aattgataaa ggaatcccaa gatgtatcca
     8401 tccaatcgat accatcataa tctattgctt cttttataac cgttatatgt tgcctaaata
     8461 ggaatcaaac aatatcgaaa aaaggaggta tgacaaaagt cacacctcct tttttcgaat
     8521 aaacggtatt caaatcagaa cactgatttc acaaccactt tatttcaggt cgttttcaat
     8581 cacctttacc gcgtaatcat ttccgttgaa acgcgctatt ttttttgcgt ccatatatct
     8641 ttctaaataa tcatcttctc ctaattgctt atggcaagaa gcaatttcat aaagcaagta
     8701 ttccaatgca taagtcgatt tatgtttctt attatactca atacccttct cacataattg
     8761 gattgcttta tcataatcct cgattttacg gtaataggtg gcgatatcat aatatacaat
     8821 gcagaccatc agattatcaa aatcagtctc actcaatatt ttaagtgtac gctccacata
     8881 aactttcgca aaatctaatt ctccttttga caagtagatc attgccacgt ttgcagctgc
     8941 ttgtaagtga tggatatctg tttcggtcgt ttgttccaac acttgattaa aataaaataa
     9001 tgctgcatct ggttttttcg cataaagatg atcaagcagt ccttgataaa ataaaatttg
     9061 atttaaaaga tcagaattac ttactttttc ctgatcgatc gtttgtaaaa ttttataaga
     9121 ttcttggtat tttgatacag aattcaatga ttgaatctca tttatttttt tcctgatttt
     9181 gtcttcttct gtttctacta atatatcgga gatctcgaca ttcagctttt tgcaaagcgc
     9241 acttaagata ttgatgcctg gcgacatatt cttgttttcg atattgctga cagttgcttg
     9301 ttcacaaatg ccttctgcta attgtacttg tgttaacccc tttttctttc ggtattcttt
     9361 tagtaatgct ccatctactt taatcaaaac aatttccttc cctttaaaaa attatttctc
     9421 ctttatatca tacacaaaaa aaagttctaa acaaccaaaa atgtttagaa cagaataaaa
     9481 attttaattt taaaataata ttcaaattaa acaactggcg tatctgctcc ttgatttctt
     9541 tttgtgttat ctgaataatt atcgtttaca gttataacac atagtgaaaa ttgtcatggc
     9601 gagaaagtct aagaatattt ttaaacataa ctatttcttt cttacgtgtg tataatgacg
     9661 acagcacacc tatcaattaa tataattatt ttattttttt atgttctcat gtttattttt
     9721 aatgacacaa cttctcgtat ttatctggca caacatataa atcgatcaaa aaattgttgc
     9781 gtgttttttt gaaaattgga gtttcaactt gattacaaaa tttaaattta gaagttgtga
     9841 aaacagcgag agacagttta atattcaaaa tatacatagg ctactcgaac gctgtgtttt
     9901 ttagtatact agtaagaaac gaagggatag actcattcca ataaggagga tttcatgaag
     9961 acaattcttt ttgctcctgc agtattcaat ttagctgaga caacacgaat gattgaggtt
    10021 gccaaagcta tgaaagaccg ttattactgt gtattctttg gcttttctaa aacttttgct
    10081 cctttgatca cagaaagtgg ctttgagtat catttactag cgccgatcct tacgaaaaaa
    10141 caagaagaac aaatcataaa atttgaccag ttgcgtacac ttaaaaaccc ttttaccaaa
    10201 gaaatggttg cctctcgtat cactagtgaa cagagtctga ttgctaagtt tgagcctcga
    10261 ctgattgtga caggttcgaa tgtgacaatt tttttatcgg cccgcaataa aaagattcct
    10321 ttagtatatg ttaaacccta tgctttgagt gaaccttttt ttcaatcaga gcatgcgctg
    10381 atgccccacg agttacgttt cttcggccct ttaagcaatc ccctttggca ctggacaaaa
    10441 aagcgtatag taaatacccg atggatcccc aatgccttca aacacgctgc acaaaaagaa
    10501 atgcttcctt taccaaaaac aagtttacaa atgatggatg ctgatctaaa tctcatcaca
    10561 acgcctaaac tatttttgga agaagaacag ctgccggaaa attatcgaat cgttggtcca
    10621 atttttgcta agctcagtac ttccttgcct gaagaagtgc taacttttat acagcgaaag
    10681 caacaagaaa gaaaacgtat tatctatttc gcaatgggta gttcaggcaa tccgcgtatg
    10741 ttacgcaaaa ttttgttctt cttacaaaaa caaccggatc tagcggttat tgcacctatt
    10801 gactatctgc ttgatgacat tcaatctgac tcagaagatc ttttaataac agaatatctg
    10861 tctagtcatc ttttgcatga attcattgat ttttctttta tccacggcgg ggaagggacc
    10921 gtccaaactg cctgtgaatc cggcaaaccg tttatcggtg tggggatgca atttgagcaa
    10981 agctgtaata ttgactattg tgtaaaatac ggaaacgcaa tcgccctcac aaaaccagtg
    11041 actgaaagaa aactgcagat tgctctgcgc gaagtttctt cacccaagat tcgtcagcag
    11101 gcacgcacgc tgcaagccgt ttttccaata aatggtccac aacaagcaat tcaagaaatc
    11161 gaaaccttcc tgagcaacca cccaatatag tttcaagtag aaaaagcttt tttaatagag
    11221 actcatcagt aatttcgcta ttcgagaccc agacagtgaa aatacaaaaa aagtaaatag
    11281 tggattgaaa agttagagtt acttaaatta cggtgtctaa aaaacacaaa atcatcctta
    11341 aaataaaaga tctgacgcta tccaaatgag cataggtagc gtctgccatt tattcttagt
    11401 caaattcttt gacacctttc tctggttgga tcatctcaac gtttcttcaa aagaaagacc
    11461 ataataatta ggcaaataca ttttcttaaa atgtgtcata tagatctaga agcatcgctt
    11521 tgtagagatt tgtgccgcta gtcccctcaa caattactaa atcaaatgta ggatttacca
    11581 ctttatcttt gataatcaac ctccctcttc tgttgagaca atgatctcgc aatccgatgc
    11641 atactcctat ataaactgcc agcaatcccc acatattgag tagatcatgt cagaatgttc
    11701 tatgtcgtca gcaacgatac actaaaagtc acgttcacca tgactgattg ctattcccag
    11761 cacaattatt tctatacacg tttcatgatt tgaataaaca ctcacatcat acatattacc
    11821 attcatacac catactgcag cccctactat atggttgtaa gctcccaaat ctatatttga
    11881 cttgatcact ttggtagtag atctactaat tctaaatcca ttgctgataa aatttccatt
    11941 ttttcctcct tctttctgcc aaaacagtta aaacaataat aatctttatg taaaaaaggg
    12001 ctgtgacaaa agccttgtca cagtcccata ttccgaataa acggtggtca aaagcttgca
    12061 tctgcggtaa taagttcaac caaacgaaaa ataagccaac atttcacaaa aatttaagaa
    12121 gcaattttcg taaatttctt cttatttctt gaagctaacc acttctgtta caaccacttt
    12181 tagaacattt aaagcttcga tgtgacaaac catctatgct gctcgatcat aaaattgata
    12241 gcaaaaattc cacaaagtac atatgtcccc catgaaaaca aaacattcat atgcggtaca
    12301 atgatctttg gaagaatcac gatcaaaaat gatgccagtg cccaaatcca tcgattgatt
    12361 tgaatatgat atgtagctag catattcaat ataaggtgac tagccgttaa taaaaagata
    12421 aaaacaaaaa ataaaatcag ccaatacatt gtttcccacc ttctaaaaac caaacttaga
    12481 cagtctggac ttcgttttct ccacgacttt gttcatctga cagcatcttt ttatcataag
    12541 cttttacaaa tggataatag ataataaatg ctatcaatgt gttgatcatg atcaagataa
    12601 caacacgcca gtcatttcct gctgaaagat aaccgccgat tggagctggt aatgtccatg
    12661 ttggcaaaac agtaaatcta ttgaccattt ctaatttgac tgcaaaataa ctgataatag
    12721 tcaaaactaa aggaactaag ttgaacggga tgaacatgta aggattcaac atcataggag
    12781 ctccaaaaat tatgggctca ttgatattga agataccagg aataatagaa aaacgaccaa
    12841 cctctttcaa gaattttgat ttacagaaga atataaacaa aacagatacc acgatcgttg
    12901 ctcctgcacc accaattgtt accgtccatt gataaaactg ttcaggagcg atatagggta
    12961 attgggtggc agctgtacca tctgccaatg cctttgcatt ctcatccaac atgatcagcc
    13021 acattggacg aacaacagcc cctacaatac tcatgccatg gataccaaat gaccacaaca
    13081 aatggatcaa aaacattggt agtaaaacac caagcaaatt attccctaaa atattggtta
    13141 aaggctcgaa taacgataat aaggcagcgt ttacatcaaa gcccgcgacg cttcgaatca
    13201 gccaagtaat tgttaaaatg actgcacctg gaatcaatgc ctcaaaacta cgggcaacag
    13261 caggtggcac ttgttctggc attttgatag taatatttcg atttttaaag aaacgatata
    13321 cttccactgc aaaaatcata gataagatcc ccgcaaacat cccagatgct cccaaagaac
    13381 tcataggtaa gacccagcca agaggtgcct cttcaggagt taaaacgttt acaggaactt
    13441 gtaacataaa gaacgttcct aaagataata taccacctgt cacactatct aatccatatg
    13501 atttagctag atccgaaccc ataacaaaag ttgcataaat agccatcaat cccatcgtca
    13561 tcctaaaggg taaaacaatc gttgccgaat aaggggcaat aaattcattc catccaggaa
    13621 acggtaaatt gataaagacc ataaaaaatg tcccaatcaa aatcaatgac aatgttgaaa
    13681 caaccccatt acgaattgct aataaatgac gctgtgtacc aatttttgcc attggtggga
    13741 caagtttctc ttcgacccat ttcatcagct tttccactaa aaccactcct tttcaataaa
    13801 atatgaacca ttcattgcat gacaacgcaa agaatgttca taactaatta tataattaag
    13861 aaattttatt tcaatatatt ctcttaaata atcaaattta tttttaagaa tcctgaaaat
    13921 aagttttcta aatcatagga gcaacaaaaa aattcgataa ttaacaaaaa tcaaaatgat
    13981 taaatctagt gattgaaaca tatcatttca aaaaaatttt gtaaattcac ccataaatat
    14041 caccctattt aacttttttc atcgtacact aaaattcaaa acaactatct ttaatcttta
    14101 cttcttggtt ttgttttaat aaatttcctt caaaaatgcc tggagaaact acaatgatca
    14161 ccgtatcttt ttgtgcttgc tccaacttct tcaaatctat aatagctaac agtgtccctt
    14221 cttttacctc ctggttactt tcaacccgta tctgaaacgg acttccttcg agttcaactg
    14281 tatctaaacc catatggatc agtatttttc tgccagattc actttcgatc gttatggcat
    14341 gtcgggtagg aaatatatta tcgattattc ctttaactgg cgcatggata tatccatcat
    14401 gattcgttat agcgtatcca actcctatca tttttgaaga aaagacctcg tcttttactg
    14461 ctgttaatgg aataatttga ccactagcta cagcttttag aatgtttctt gttttaaaga
    14521 aatgcacttt ttatcacctc tactttaatg ctggccaata ttttttgttt actttgatca
    14581 tttcatctag tatttttttt gcgactctgg catttggtac ggtttgattc aatgtaaatg
    14641 cttgtaaagc tttttgataa gaaccttcaa agtaagcatc tactagtaac ttctctactg
    14701 caacttgtgc ctccatcaat cctttatgaa aatcactgat tggttttctt agtgtaattg
    14761 gctccacacc agttgcacca acatatgccg gtatttcaac aactgcatct gaccgtagat
    14821 tcggaatcgc cccttgatta ggaacgatta gcataaagcg acgacgatca tcattcaaca
    14881 aggaaatagc tatatcgacg atatattgtc catgctcccc aaaattaaag ttcaatactt
    14941 cttccacaat accgcggcgt attttatcag ccatttcttt ggtatttttc tctcgtccat
    15001 ccatgaccat attagcacgt gtatactctt tgtcagtatg ctcaacgacc atatcaggat
    15061 ataagtaata ctctaagtaa ttattcggga tattacttgg aaaatttttc gtgatgactg
    15121 acatcatttg aaaggttttt tgccaagttt tatctcctat attaaaatcg gcgacttgca
    15181 tttcttttgt tattagtttt tcaataatct ctggcataat ttctcgttgc aattctttat
    15241 cataaatcga tgtataccag ccaaagtggt ttaaaccata atacgtaacg atccaattct
    15301 tacgatcata accgtaattc actgcaatcg tttcttcaat tgaaatagtc atatcacagg
    15361 cattaatcat ttttacattc ggatatttac gacgaacagc ttcagaaacg atcgactctg
    15421 gatttgtata attcaaaatc catgctttgg gggcatagtc ttgtatatga tcgacaattt
    15481 ccaataaacc tttgattgag cgcatcccat aagcaaatcc tccgagtcca cacgtttctt
    15541 gtcctactaa tccatgttta agtggaatct tttcgtcctt ttctcgcatc tccaatcctc
    15601 caacacgaat ttgtgagaaa acaaaatcgc gtcctgtaaa agcaagcttt ggatcatccg
    15661 ttgcacgaat gcgaatattt gaaaaacctt ttcttttcag cataaattta acaatcaagt
    15721 acatatccat atttctttct tcatcaatat catataaacg tatttcagat aatggcaacc
    15781 gtttttcatt gttcaaaatg gcttgaacga ttcctggtgt atacgtactc ccgcctccag
    15841 ctatagtgat aatctgtttt ttcatcatca tcttttcctt tctattcttc taataattta
    15901 ttgaattctg ccataacata agtcacttct aagccgatga taatttgata atttttttca
    15961 gttggtttaa tgatcccgct tatccctaat tgcttgattc gctgttcctc gaccatggtg
    16021 ggatccacta cctctacccg taggcgtgta ttacaactat agacatccag gatattggct
    16081 tttcctccaa acgcttgtag catttttgtt gccatatatt cataattttt acttgctaac
    16141 cctaactctg tttcttctaa ggttacttca ttgccaaact ctgccttagc ttcacgtcct
    16201 aatgtctgaa tgtttctctt attgatcaaa taataaaaag taacgtaata caaggcaaaa
    16261 aagaaaattc cgattggaag aatcaaaata gcattggtag cgattcgaaa attgatgaga
    16321 taatcaacaa tacatgctcc gaatgtaaaa ccaattcgta tattgaataa gtaacagaca
    16381 atccctccta aaccggcaaa aagtgcatgg atcacgtaca acataggaga aagaaacatg
    16441 aaactaaatt caacaggctc agtgatattt gcaataaatg aagttcctgc accgcttccc
    16501 atgattcctt tgaccatctc tttattttct ttataagctg ctttatagat agctagacat
    16561 atagctggta taccaaacat cattactaca aaaaaaactg ataaaaacag tccagcctga
    16621 ggatctccgt tgataaagcg tgtcatctct cctctgaaaa cttccttgct aggagatgta
    16681 tagcttccta aatcgtaata aatatacgta ttcaacacat ggtgcagtcc aaaggggatc
    16741 agcaaacgat tcaaaaacat aaatatcccc acacctaatg ctcccatatc aacgagcagt
    16801 tttgcaaaat tatcaatccc aatttggatg agcggccaga taaagcccaa aaaaacagct
    16861 gcgattgttt gtagaatcat caccatagtc aatgggaatt tttcgcccgc aaaataagaa
    16921 aaaactactg gtaatttttg ttctttaaag cgattatacg tccatgccgc tactaaaccg
    16981 gaaataattc caccaaaaat ccccatattc acttctgggt ccataatttc taagcctttt
    17041 ttcaaggtag caatcgctaa aaaaccagta agtgcaggta ttcctttgtc cttatttttg
    17101 acaaaaccga ttgcaactcc tatagcaaat aagatatcca agtttccaaa aacggcattt
    17161 ccagctgcac caattactgg gatgttcagc atatcgtcag ctgataaacg catgatcaat
    17221 cccgctaatg gcatcgctgc aactggaagt agcatcgctc ttccaagctt ctgcacattt
    17281 gatttaacat tcatttttat tcctcctcta ttaaatatcc tcatatgtta ctaactcaat
    17341 caaaggatca tttttcactt tttgagcaaa tgctgaatga attaaaaatt cgacttggtg
    17401 ggtacgagga tacacaaaac ttgaaccatt taacaattcc tgatccaaat acgctgcgtg
    17461 acacatgact tcgatcgttt tatcttctct caatatcatg agtaaacttg ccaaatattc
    17521 ttccacactc gtattgattt gtcgtttttt ttcatcagtt tctcctacga catcgaaaca
    17581 aggctcaaaa taatcgacat gacgaacttc atcttttcgt tcaaagttgc tccgaaccgg
    17641 caaatcatat ttttttgcta atgtaacaac tacctcctga ttttcatcca aagtatgagt
    17701 atgatgatga ctgtctaaat gagttggtat gatccccgca tgataaattt tttgaatctg
    17761 agcattccat tcctgataca gttgatcttt gtcaatgtta aatggatgct gataataaga
    17821 taaggatctg aactctccgc tttcgataag agtatcgaca gttttgagga gtggtttgcc
    17881 acacgtcaat gttaaatgga ctcctacacc tagcctaggc atttcctttc ttagtttcac
    17941 agcatgctcg aaacccggca tatttgccat caatgtagtt gatgtcaaaa ttcctcgctg
    18001 ataagcatcc ataatcccat aattcacacc atggctatag ccaaaatcat ccgaattaaa
    18061 aatcactttt cccatttcat tctccttctt ttttctacta aaataggcgc aaccaaataa
    18121 tcatagtcca tttactatgt gtcatttggt tgcgcctata gatagttacg cccttatttt
    18181 aatagattct tgctagatga attgccaaat agatgatttc attttcttga atggcaagtt
    18241 gaaattgctg ttcgatgata tctttaatct ttagtgctgt acaatacgct ttgctatgtt
    18301 taaatgtttc agtaaaaaaa ccaatatttt ctactggcgt ttcttcctga taaatcaagc
    18361 gtttaaccag gaatttgata tgaaccatta agcgatgata agtcagtgat tctttatcat
    18421 aaacgtttga ataggatttt tctagatggg acaaaatcgt ggtcgtcatt tctactattt
    18481 ttaagctctt taaactatta ggctctccta gctcagcatt aatgatatgc atagtgatga
    18541 atcctacttc atttgaccct aactcggttt gatatcgatg attgattcgc tcgaccactt
    18601 ctactgctat atcatattca tttggataaa ggaatctcat ttctggcaac ataattgctg
    18661 tgacatctct atcttctctt tttcgttgaa tagcaaaata aatatgatct gtcaatgtaa
    18721 tatagatatt tgaatctaat ggagaggaga tcctagctgt tatcagttca atcacttctt
    18781 ccgcaaaatc cataaattcg attggaatct gcgagactat ctcactgaat cgtttgatct
    18841 tttctttaga atctaataca aataatttgt cagcatcctc aacatcaaat ggcttactca
    18901 ctttagcaga aaagccaatc cctttcccca tcgcaatttt ttctattcca tcgtcatcga
    18961 ccaatacagc attatgattc agctttttca tcacatacac cgttaattca cctcctctat
    19021 atgataaaac aaaacaactt gcagactcct tcatacatat ttttgtctcc aaacaatttt
    19081 taaagacaaa aaacgaccta agaaagaacc ctttcttagg tcgtgcctaa ttgaatagta
    19141 gcaccctaca taatttacaa aaatagttta acacataata aaagcgttat caatatcttt
    19201 tttactcgtt ttatgataat acttgtatcg aattgatttg gaggtaatta cataaaaaca
    19261 aaaaaaatat agcaactctc tataagaaag ttgctatatt gataattata ccggcggccg
    19321 gggtcgaacc ggcacgtcct caacggacac tggattttga gtccagcgcg tctgccaatt
    19381 ccgccacgcc ggcaaattta aaaataataa ctggggtagc tggattcgaa ccaacgcatg
    19441 agggagtcaa agtcccttgc cttaccgctt ggctataccc caagaataaa gggcgaatga
    19501 tgggaatcga acccacgaat gccggagcca caatccggtg cgttaaccac ttcgccacat
    19561 tcgccatcat aaaagatgtt atttaatttc tcaataaaaa actaagatga agacatctta
    19621 gtcaataccg gcggccgggg tcgaaccggc acgccctcaa cgggcactgg attttgagtc
    19681 cagcgcgtct gccaattccg ccacgccggc aagttgattt attagtacta aggcggtaac
    19741 cggatttgaa ccggtgatga aggttttgca gacctctgcc ttaccacttg gctataccgc
    19801 cattatacta ttatcaatct ataaaataaa gaataaatta tagaaactgg ggtagctgga
    19861 ttcgaaccaa cgcatgaggg agtcaaagtc ccttgcctta ccgcttggct ataccccaag
    19921 aataaaaagg gcgaatgatg ggaatcgaac ccacgaatgc cggagccaca atccggtgcg
    19981 ttaaccactt cgccacattc gccatggcag gggcagcagg aattgaaccc acactaacgg
    20041 ttttggagac cgctgttcta cctttaaact atgcccctat aaaatggagg agagtggatt
    20101 cgaaccactg aaccctaagg aacggattta cagtccgtcg cgtttagcca cttcgctact
    20161 cctccatggt ggcgcgggac agaatcgaac tgccgacaca cggagcttca atccgttgct
    20221 ctaccaactg agctaccgcg ccatatttta aaattattaa ttgaataaca agaacgacgg
    20281 ttccgacggg aatcgaaccc gcgatctcct gcgtgacagg caggcatgtt aacccctaca
    20341 ccacggaacc agttcattat ggaggttaac gggatcgaac cgctgaccct ctgcttgtaa
    20401 ggcagatgct ctcccagctg agctaaacct ccaacattca attaaaatga cccgtacggg
    20461 attcgaaccc gtgttaccgc cgtgaaaggg cggtgtctta accgcttgac caacgggcca
    20521 ggtaaatttg ctacggagag taagggattc gaacccttga gacagtttgg caccatctac
    20581 atgatttcca atcatgctcc ttcggcctct cggacaactc tccagagtga aagaagctca
    20641 atactctttc tcaaaatgag aactccggca gtaggactcg aacctacgac atcatgatta
    20701 acagtcatgc gctactacca actgagctat gccggaataa catcagcgtg gcgacgtcct
    20761 actctcacaa ggggcaaccc ctcactacaa tcggcgctaa gaagcttaac ttctgtgttc
    20821 ggcatggtta caggtgtatc cttctcgcta tcgccaccac actgtggtgt tatcttttat
    20881 tgagtaaatt ttgttcactc aaaactggat ttgaagtcac ataagttttt ttccgagt
//
LOCUS       DAFBVQ010000048        20784 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.050, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000048 DAFBVQ010000000
VERSION     DAFBVQ010000048.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20784)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20784)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20784
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.050"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(20..1576)
                     /gene="rny"
                     /locus_tag="LLC22_001981"
     CDS             complement(20..1576)
                     /gene="rny"
                     /locus_tag="LLC22_001981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875117.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease Y"
                     /protein_id="HBK5435240.1"
                     /translation="MVFNILLAIIGLIVGLGLGFMVAKSRHEKEIAGAQSSAAGIIDS
                     AKKEAETLKKEALLEAKEENQKYRSEVESELRESKLELKSQENRLIQREQTLNRKDDS
                     LEKRENSLESKEEALSSKQQLIEEREKDVEKMIEDQQKELEKIAGLSKEDARDVIMKS
                     TEEELNHELTLMVKESEQRAKEEADRKAKNLLSLAIQRCAADQVSETTVSVVTLPNDE
                     MKGRIIGREGRNIRTLETLTGIDLIIDDTPEAVVLSGFDPIRREIARMTLEKLIQDGR
                     IHPARIEEMVEKSRKEMDERIREYGEEAAFEVGAHTLHPDLIKIIGRLRFRTSYGQNV
                     LKHSVEVAKLAGILAAELSEDIQLAKRAGLLHDIGKALDHEIEGSHVEIGAELAAKYK
                     ENPVVINAIASHHGDVEATSVISVLVAAADALSAARPGARSESLENYIRRLRSLENIS
                     NSFAGVESSYAVQAGREVRVMVKPEEISDLDAVRLVRDIRKRIEEELDYPGHIKVIVI
                     RETRATDYAK"
     gene            complement(1987..3036)
                     /gene="recA"
                     /locus_tag="LLC22_001982"
     CDS             complement(1987..3036)
                     /gene="recA"
                     /locus_tag="LLC22_001982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318847.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase RecA"
                     /protein_id="HBK5435241.1"
                     /translation="MADDRKAALDAALKKIEKSYGKGSIMKLGEKIDQQISTIPSGSL
                     ALDVALGVGGYPRGRIIEVYGPESSGKTTVALHAIAEVQKNGGTAAFIDAEHALDPQY
                     AQKLGVNIDELLLSQPDTGEQGLEIADALVSSGAVDIVVVDSVAALVPRAEIDGEMGD
                     SHVGLQARLMSQALRKLSGSINKTKTIAIFINQIREKVGVMFGNPEITPGGRALKFYA
                     TIRLEVRRAEQLKQGTDIVGNRTKIKVVKNKVAPPFKIAEVDVMYGLGISQEGELLDM
                     AVEKDIVDKSGAWYSYKEDRIGQGRENAKIYMANHPEMMAEVSALVRAAYGIGEEVAV
                     PEDEKGQEELPLVEE"
     gene            complement(3145..4386)
                     /locus_tag="LLC22_001983"
     CDS             complement(3145..4386)
                     /locus_tag="LLC22_001983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="competence/damage-inducible protein A"
                     /protein_id="HBK5435242.1"
                     /translation="MKAEIIAVGTELLLGQVVNTNATFLSEQLADLGIEVYYQTVVGD
                     NQQRLEELIALAETRSELILLCGGLGPTEDDLTKEATAAHLGKSLIQNTEGYKKLLAY
                     FETTHRKMTKNNLQQSQIIEGGVPLPNRTGLALGTFYQTDTHAYILLPGPPNELKPMF
                     VEQVRPLLEERFPSEEKLISKVLRFYGIGESRLVTELKDLIETQINPTIAPYAKPNEV
                     TLRLTVKTNDVQAGNQALLALEEKIQERVGEYFYGYGDDNSLAKVVVELLKENKQTVT
                     AAESLTAGAFQAALGDIAGVSEVFPGGFVTYSLQTKAGFLEIDPELLAEYGTVSKECV
                     EQMAIQAREIARTDYSVAFTGVAGPDTLEGQSAGTVWIAISSKDGVVSEKYHFARDRA
                     AIRYNAVMQGFDLLRKQLLRK"
     gene            complement(4626..5204)
                     /gene="pgsA"
                     /locus_tag="LLC22_001984"
     CDS             complement(4626..5204)
                     /gene="pgsA"
                     /locus_tag="LLC22_001984"
                     /EC_number="2.7.8.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CDP-diacylglycerol--glycerol-3-phosphate
                     3-phosphatidyltransferase"
                     /protein_id="HBK5435243.1"
                     /translation="MNLPNKLTVLRICMIPIFILVVGLPLDWGQFNVGDTTLAVTQLV
                     GAVIFALASITDWLDGKIARARGLVTNFGKFADPLADKMLVMTAFIMLVDQGKAPGWV
                     VAIIVCRELAVTGLRLLLVEHGEVMAAAWPGKVKTATQMVAIILLFINNIPFSLIGIP
                     VDQIMLYACLIFTIYSGVDYFIKNSGVFKGSM"
     gene            complement(5413..6336)
                     /locus_tag="LLC22_001985"
     CDS             complement(5413..6336)
                     /locus_tag="LLC22_001985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435244.1"
                     /translation="MLRRIKQTGEDERVAFETIGEKLRQARLNKKISLDELQQITKIQ
                     KRYLEAIDNDDFDQLPGKFYVRAFIRQYAEAVGEDGDHLVDVFDGKSKLTGSVPERPQ
                     PETVSTSRKAMHQEESHPSRFWTSLPVILLGLVALAIVVVVGYMTWQDRQADPIIGDT
                     ASSLKVEGSVEESSSSEQSTQTKESSTVESTTKSSEEKKMAIATGEDSGSAIAVNITD
                     ATKPVTLEFTAVNRVWLGVLVDNAYVYQGTLAANETQSTVLPETATNATITIGAASNA
                     TIKANGESVPVNPGENNQSPKNVNLTLQYAE"
     gene            complement(7075..8361)
                     /locus_tag="LLC22_001986"
     CDS             complement(7075..8361)
                     /locus_tag="LLC22_001986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287425.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBK5435245.1"
                     /translation="MNKTEYEQINETLYHEVLPNGLTVYLLPKNDYHKTYGLFSTNYG
                     SIDNEFIPYGEKEKVKVPDGIAHFLEHKLFEKEDGDVFQLFGKQGASANAFTSFTKTS
                     YLFSTTDQVEKNLTTLIDFVQAPYFTEETVNKEKGIIGQEIQMYEDDPNWRMFFGILN
                     NLYPTHPLHIDIAGTVESIDKITAQDLYTCYRTFYQPSNMVLFVVGKMEPEKLMKLIR
                     ENQEAKNFPPKQEIVRYFPENTKEIIKQSALEAAITRDKFVLGIKGLDTLPQEGTELL
                     RYKTAINLLFQMILGNTSRNYLAMYNQGIIDDSFGFEFSLDREFHFADFSGDTDEPEK
                     AAEKVKEIILGFADDPEVSETNLDLLKKKMLGQYFQSLNSIEYIANQFTQSLFGDRTL
                     FDLPEIIDSIQMKDVLAAGEAFISEEAFSEFYMRPK"
     gene            complement(8354..9622)
                     /locus_tag="LLC22_001987"
     CDS             complement(8354..9622)
                     /locus_tag="LLC22_001987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="insulinase family protein"
                     /protein_id="HBK5435246.1"
                     /translation="MVYQLAEGVNLHVLPTKQYKTIRIFIRFTARLQQEVITKRSLLS
                     SMLETNSLNYPDQTKLSAQLAELYGASFGLSVRKKGNLHWLNAGISFVNGEYVNDPNL
                     FSQAVDFLKEVLFYPNIKNHQFDQLTFDLEKNNLRLYLESLKEDKQTFASYALQELYF
                     ENSPEQKIPGLGVVEDLDKITASSLASYYQEMMANDQIDIFVVGDVDPDKAAEAVGQL
                     PFESRETVYPDLFYTQPQVNIVKERQVREPIVQAKLNLAYQTNVYYDEPERFALMVFN
                     GLFGGFPHSKLFMNVREKESLAYYASSSVDTFRGFMSVQTGIDEKNRNQVLHLIHEQL
                     ESLRNGEITELELSQTKAMLRNQYLLSLDSPQAAIEASFLDSWLPETKLSDEEWLKRM
                     ESVTIKEIQQVAEQIELQAIFFLAGGNANE"
     gene            9874..10335
                     /gene="mscL"
                     /locus_tag="LLC22_001988"
     CDS             9874..10335
                     /gene="mscL"
                     /locus_tag="LLC22_001988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373373.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="large conductance mechanosensitive channel
                     protein MscL"
                     /protein_id="HBK5435247.1"
                     /translation="MIKEFKEFIMRGDVLDLAVGVVIGSAFTSIVNQVVQGLITPLIG
                     WFVAMITGTSDLEGALSILDWSPTKGVTFAFGNVISAIITFLITGFVLFLVVKAANRA
                     KNLRSKEEQVEVEETPTAEDYLSDIRDLLAKQVAEDNTHPVEQTNLSDTSK"
     gene            complement(10394..10840)
                     /locus_tag="LLC22_001989"
     CDS             complement(10394..10840)
                     /locus_tag="LLC22_001989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5435248.1"
                     /translation="MEYQVKKFEELSTAEFYAIVKERIAVFVVEQQCPYQEVDDIDGQ
                     AWHTFFQDTDGKILAYTRVYEEAESIHFGRVLVHQDNRKDGLGRKIVQETINMIQKNF
                     PEKPIVIGAQEYLQAFYESFGFKAISDVYLEDDIPHIDMKKEQVAS"
     gene            complement(10933..11178)
                     /locus_tag="LLC22_001990"
     CDS             complement(10933..11178)
                     /locus_tag="LLC22_001990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750133.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Veg family protein"
                     /protein_id="HBK5435249.1"
                     /translation="MPTTLASIKKDLEGRIGSPIMLVAQTGRKRQTERRGVLTETYPS
                     VFVVDLDPEENSFERVSYSYSDVLTRTVEIEFLTEAV"
     gene            complement(11292..11870)
                     /locus_tag="LLC22_001991"
     CDS             complement(11292..11870)
                     /locus_tag="LLC22_001991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314323.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5435250.1"
                     /translation="MSEELLRAARNGDEEAFAALYQKYFPLLLRLKNTYYLRNYVSED
                     WEQEARIALYQALRTYEKSKGVSFGSYYKSIISNQIYSLLRKQNALKRRDQKDEVSID
                     QKIETEGPDFLAEITLQEPLAIQHLLLKEAIENCEIQFSKIEAKIFHYYMQGVDFVDM
                     AECLAMDHKQVMSAYGRVKLKIKKHLKFYNEE"
     gene            complement(11947..12477)
                     /locus_tag="LLC22_001992"
     CDS             complement(11947..12477)
                     /locus_tag="LLC22_001992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332254.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NYN domain-containing protein"
                     /protein_id="HBK5435251.1"
                     /translation="MKKQLLIVDGYNMIGSWPELVQLKKQDKMADAREALLHRLSNYA
                     KYEGMEVIVVFDAQLVPGIQQNYKKYQLDVVFTKEDETADSYIERIAGQLNDRLTQVT
                     VATSDLAEQWMIFSQGALRTSAYELYKTIKKTEKTIAQENKDMHFIDFRRNSPWNEEQ
                     LKKLSQKLDDLMRKNK"
     gene            complement(12481..13341)
                     /gene="rlmB"
                     /locus_tag="LLC22_001993"
     CDS             complement(12481..13341)
                     /gene="rlmB"
                     /locus_tag="LLC22_001993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373371.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (guanosine(2251)-2'-O)-methyltransferase RlmB"
                     /protein_id="HBK5435252.1"
                     /translation="MGKERTNKHQSKRGFEDKKQNRYSNKKQTGRNQSVSDQNEEALE
                     DNFVFGHHAAVEALQQGRGNKLFLQEDSRGEKVEELKEIAREQAVPVKWVPKQKLETL
                     SDHGVHQGVVLAITPYEYLSLDQLIERTKEKKEDPFFLILDSIEDPHNFGSILRTADA
                     SGVDGVIIPKHRAVGITPIVTKTSTGAVEHVPVARVTNLVQAVQQLKETGFWVFGTDM
                     TGTNFQKWNAKGSIALVIGNEGKGMSPGLKKEMDELLTIPMTGHVQSLNASVAAGLLM
                     YQAFSQRQGE"
     gene            complement(13334..13729)
                     /locus_tag="LLC22_001994"
     CDS             complement(13334..13729)
                     /locus_tag="LLC22_001994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Mini-ribonuclease 3"
                     /protein_id="HBK5435253.1"
                     /translation="MRDYTQLNGLALAYVGDAIYEIYVRDHLIDQGETKPNKLHRAAT
                     NYVSANAQAFLIQQMLEEHLLTEEEELYYRRGRNAKSHTSAKNADVTTYRVATGFEAL
                     MGYLHLTKQTERMEELIRWCIQKVGEKNG"
     gene            complement(13726..15138)
                     /locus_tag="LLC22_001995"
     CDS             complement(13726..15138)
                     /locus_tag="LLC22_001995"
                     /EC_number="6.1.1.16"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287445.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine--tRNA ligase"
                     /protein_id="HBK5435254.1"
                     /translation="MIKIYNTLTRKKEEFIPIQKGHVGMYVCGPTVYNYIHIGNARST
                     IAFDTIRRYFEYRGYKVDFVSNFTDVDDKIIRTANELGITAPEVADRFIRAFEEDTKA
                     LNVEPATLHPRVMDHMPDILAFIQVLVEKGYAYESSGDVYYRTRKFENYGKLSDQSID
                     ELEVGASQRTGEEQQQKEDPLDFALWKQAKPGEISWDSPWGKGRPGWHIECSVMATKH
                     LGETIDIHGGGQDLEFPHHENEIAQSEAKTGKKFANYWMHNGYVTIGEDDEKMSKSLG
                     NFITVHEMIKNVDPQVLRFFMATTQYRRPIRYSETTMKEAATNLQRLKNTFDNLKFRQ
                     ETASENLADDADKIALLENLEQRFIEEMDDDFNAANGITVVYELAKWLNTYLDQPKVS
                     AAVLAQGEALFSQWLSIFGILFTAEELLDEEIEQLIEERNQARSNRDFVRSDEIRDLL
                     KEKGILLEDTPQGTRWRREA"
     gene            complement(15135..15671)
                     /gene="cysE"
                     /locus_tag="LLC22_001996"
     CDS             complement(15135..15671)
                     /gene="cysE"
                     /locus_tag="LLC22_001996"
                     /EC_number="2.3.1.30"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine O-acetyltransferase"
                     /protein_id="HBK5435255.1"
                     /translation="MSWFTRAIDAAKRNDPAARSTAEIVLTYPGFHALFWHRFSHFLY
                     QHRLFLLAKINAQFWRFLTGVEIHPGATIGTGVFIDHGMGIVIGETAEIEDDVILFHG
                     VTLGGTGKETGKRHPTVKQGAMLSANAQILGPVTIGKNAKIGAGAVVLKDVPDDATAV
                     GVPAKVVRIKGEKVRRSE"
     misc_binding    complement(15757..15996)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(15993..17453)
                     /locus_tag="LLC22_001997"
     CDS             complement(15993..17453)
                     /locus_tag="LLC22_001997"
                     /EC_number="6.1.1.17"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287447.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate--tRNA ligase"
                     /protein_id="HBK5435256.1"
                     /translation="MTKVRVRYAPSPTGHLHIGNARTALFNYLFARHNDGDFIIRIED
                     TDQKRNIEDGEKSQLENLAWLGMNWDESPENPGEYGPYRQSERKEIYQPLIDQLLASN
                     RAYKCYCTEEELEAEREAQRARGEMPHYAGTCANLTPEEQAEKEAQGLESVVRFRVPR
                     NTEYAFTDMVKGAISFESDNIGGDFVIQKRDGMPTYNFAVAVDDHLMKITHVLRGDDH
                     IANTPKQLMIYEAFGWTPPTFGHMTLIINSETGKKLSKRDESILQFIEQYRELGYLPD
                     AMFNFIALLGWSPVGEDEIFEHQELIKMFDPKRLSKSPAAFDAKKLQWVNNHYIKAMD
                     LDAFTDMCLPYLIADGRVAENPDEKTIEWVKKIVSLYQPQMSYAAEIVDLSTLFFNEH
                     PVLNEAAKEVLAGETVPTVLHAFKAQLEQMEVVDAPTVKAAIKAVQKETGVKGKNLFM
                     PIRVAVSGQMHGPELPETIELLGREKSLAHLNQVLN"
     gene            complement(17623..18780)
                     /locus_tag="LLC22_001998"
     CDS             complement(17623..18780)
                     /locus_tag="LLC22_001998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002400946.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PIN/TRAM domain-containing protein"
                     /protein_id="HBK5435257.1"
                     /translation="MQKRVITLLMIIVGASLGISFLPSAWQAIGQQSNGWLNNTFTNS
                     LLGALIFFLLSLLLAKHISAIIKQVEQKLSEVSLTYLLFGAIGAIIGLTLGVVISTPL
                     YNMEIPFVNSVLPILLMIILGYLGLRMGTTRIEEWKKVFGSRSKKIEQETASQVESQL
                     LERKSGENFHKYKILDTSVIIDGRIYDITKTGFLEGTLMIPNFVLYELQYIADSGDSL
                     KRVRGRRGLDILNALQKEEGISVEMYDGDFEDISEVDSKLIKLAKLLDGVIVTNDYNL
                     NKVSEFQNVPVLNINALANAVKPVVIPGETMNVLVVKAGTERQQGVAYLDDGTMVVVE
                     DGQHYMNERIEVVVTSALQTAAGRMIFAKPAHAGRGIDNKKETEKKTKQSK"
     gene            complement(18814..20184)
                     /gene="radA"
                     /locus_tag="LLC22_001999"
     CDS             complement(18814..20184)
                     /gene="radA"
                     /locus_tag="LLC22_001999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624348.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RadA"
                     /protein_id="HBK5435258.1"
                     /translation="MAKKSKVQFVCQNCGYVSPKFLGRCPNCGKWNTMVEEIEQDTTD
                     RRTRTSLTGEKAKPTKIADVVPKKEPRIKTKLEELNRVLGGGVVPGSMVLIGGDPGIG
                     KSTLLLQVSQQLAAIGGKVLYVSGEESAEQIKLRAERLGSINTEFYLYAETDMNEISR
                     AIEHISPDYVIIDSIQTMTQPDITSVAGSVSQVRETTAELLKIAKTNGIAIFIVGHVT
                     KEGSIAGPRMLEHMVDTVLYFEGEQHHSFRILRAVKNRFGSTNEIGIFEMHEHGLEEV
                     ANPSQIFLEERLDGATGSAIVVAMEGTRPILVEIQALVTPTMFGNAKRTTTGLDFNRV
                     SLIMAVLEKRAGLLLQNQDAYLKAAGGVKLNEPAIDLAIAVSIASSYKEKGTQPTECF
                     IGEIGLTGEIRRVSHIEQRVKEVQKLGFTKVYLPKNNLGNWEAPKGIEIVGVATLAET
                     LKRVFR"
     gene            complement(20247..20774)
                     /locus_tag="LLC22_002000"
     CDS             complement(20247..20774)
                     /locus_tag="LLC22_002000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dUTP diphosphatase"
                     /protein_id="HBK5435259.1"
                     /translation="MRKRGFEVISKYKDQNINLPQRATHHAAGYDFEAAEEVVIPSIW
                     KAGWKKGLETVADGLKKDVSENEKQLKPTLVPTGIKAYMGEDEFLQLANRSSNPLKRF
                     LVLTNGVGVIDSDYYNNEANEGHIMFQFTNFGFKDVVIKKGERIGQGIFLPFLKADQD
                     QTTAQRQGGFGSSSK"
BASE COUNT         5473 a         4592 c         3706 g         7013 t
ORIGIN      
        1 tcttcttttg tattttttat tatttagcat aatcagttgc acgagtttcc cgaataacga
       61 ttactttgat gtgtccagga taatccagtt cttcttcgat tcgtttacga atatcacgta
      121 ctaaacgaac agcgtctaaa tccgagattt cttctggctt gaccattacc cgaacttcgc
      181 gtccagcttg aactgcgtaa cttgattcta caccggcgaa gctgttcgaa atattttcca
      241 gacttcttaa acgacggatg tagttttcta atgattcact tcgcgcacca ggtcttgctg
      301 ctgagagcgc atctgctgca gctacaagga cagagataac agaagtagct tccacatctc
      361 catgatgaga agcgatcgcg ttgattacta ctgggttttc tttgtacttg gcagctaatt
      421 ccgcaccgat ctcaacgtga gatccttcaa tctcatggtc aagtgctttc ccaatatcat
      481 ggagcaaccc ggcacgtttt gctaattgga tatcttcgct aagctctgct gctaagatac
      541 cagctaattt tgcaacctcg accgaatgct tcaagacgtt ttgtccataa ctagttctga
      601 atcgcagacg tccgatgatc ttgattagat ctggatgaag tgtatgagca ccgacttcaa
      661 acgctgcctc ttccccgtat tcgcgaatac gttcatccat ttctttacga gatttctcga
      721 ccatttcttc gatacgcgct ggatggattc gtccatcttg tatcagtttt tccaaggtca
      781 tccgtgcgat ttctcttcgg attggatcga atccggaaag aacaactgct tccggtgtat
      841 catcgatgat taaatcgata ccagtcagcg tctcaagcgt tcgaatatta cgaccttctc
      901 gtccaatgat acgacctttc atttcatcat tcggaagggt aacgactgaa acagtcgttt
      961 ctgaaacttg atctgctgcg cagcgttgaa tcgctaatga taataagttt ttcgctttgc
     1021 gatctgcttc ttctttggca cgctgttcag attcttttac cattagagtt aactcatgat
     1081 tcagctcttc ttcagtcgat ttcatgatga catctcgtgc gtcctctttt gataaaccag
     1141 caattttttc tagttctttt tgttgatctt caatcatttt ttcaacgtct ttttctcgct
     1201 cttcaattaa ttgctgtttt gaactaagtg cttcttcttt actttcaagt gagttctcgc
     1261 gtttttctaa cgagtcatct ttacgattca gcgtttgttc gcgttgaatc aaacgattct
     1321 cttgagattt taattctaac ttactttctc tcagctcact ttcaacttca gaacggtatt
     1381 tctgattttc ttccttagct tctaacaatg cttctttttt tagagtttct gcttcttttt
     1441 ttgcactatc gatgattcca gcagctgatg attgtgcacc agctatttct ttctcgtgac
     1501 gtgactttgc gaccataaac cctaaaccaa gaccgacaat taaaccgatg atagcgagga
     1561 gaatgttgaa taccataaaa tccacctcca tactatcttt ttcattttta tcatctatac
     1621 agcttctatg ataaattatt ctaaactcgt caatatgcat cttcgcatat atgtgtacaa
     1681 aaaacatgca caactttatt ctaatgtttg taccccgtag tgtcaacttt aaataaacaa
     1741 agaaacggct ttctacttat tcattaaacg atggttttta aaataaatga cactagtttc
     1801 atataggtaa acctttaaat tgagaaactt ttctattaaa ttattctttg tagatgaaca
     1861 gatattttta ttttatgtac ccactcgtat aattaaataa ctcacgattt ctttattcaa
     1921 taaaaaaacg gcaggtcaag gagagtacct actcttcaga ccagccgttt ttgtttatca
     1981 taatttttat tcttctacta aaggcaattc ttcttgtcct ttttcatctt ctgggacagc
     2041 gacttcttca ccaataccat aagctgctct aactagagca gaaacttctg ccatcatttc
     2101 aggatgatta gccatataga ttttagcgtt ttcccgtcct tgaccaatcc gatcttcttt
     2161 ataagaatac caagcaccgc ttttatcaac aatgtctttt tctactgcca tgtctagaag
     2221 ttctccttct tgtgagatcc ctaaaccata catgacatct acttcagcga ttttgaaagg
     2281 aggtgctact ttgtttttta cgactttgat ctttgtacgg ttaccaacaa tatctgtacc
     2341 ttgtttcaat tgttctgcac gacgtacttc caaacggatc gttgcgtaga atttcaatgc
     2401 gcgtcctcca ggagtgattt ctggattccc aaacatcacg cctacttttt cacggatttg
     2461 gttgatgaaa atagcgattg tttttgtttt gttgatcgaa ccagagagtt tacgcaatgc
     2521 ttgagacatc aaacgtgctt gtaacccgac atgtgagtca cccatttcgc cgtcgatttc
     2581 tgctcgtgga actaaagcag caactgaatc gactactacg atatctacag ccccacttga
     2641 tactaaagca tcagcgatct ctagaccttg ttctcctgtg tcaggctgtg aaagaagtag
     2701 ttcatcgata ttcacaccta atttttgtgc atattgcgga tctaacgcat gctcagcatc
     2761 aatgaaagcg gccgttccgc catttttttg tacttctgca atagcgtgta gtgcaactgt
     2821 tgttttacct gaactttcag gtccatatac ttcgatgata cgtccacggg ggtaaccgcc
     2881 gacacctaaa gcgacatcta acgcaagaga gccacttgga attgtagaga tttgttggtc
     2941 gattttttcg cccaatttca taatagagcc tttaccatag ctcttttcaa tttttttcag
     3001 tgcagcatct aaggctgctt tacgatcatc tgccaatacg ataatcctcc ttatatttac
     3061 aaatcagagc aacatttcat tatccttatc atatcttttt tagtgaaaaa aagcaagaaa
     3121 aaaccgaaca aatattcgca tttatcattt tcttaaaagc tgttttctca aaagatcaaa
     3181 tccttgcata accgcattat atctgatagc agcacgatct ctggcaaagt gatatttttc
     3241 cgaaaccacg ccgtctttag atgaaatagc gatccatact gttcctgcag attgaccttc
     3301 taacgtgtcc ggtccagcca ctccggtgaa agctacactg taatctgttc ttgctatctc
     3361 acgtgcttga atggccatct gctccacaca ttctttgctg actgttccat attctgctaa
     3421 tagctccgga tcaatctcca gaaaaccagc ttttgtttgg agcgagtagg taacgaatcc
     3481 gcctggaaat acttcagata caccagcaat gtcgcctaat gcggcttgga aggcgccggc
     3541 tgtcaaactt tccgctgctg ttacagtctg cttgttttct ttcagtagtt ccactacgac
     3601 ttttgctagc gaattatcat cgccgtatcc ataaaaatat tcccctactc gttcttggat
     3661 tttttcttct aatgctaaaa gagcttgatt ccctgcctga acatcatttg ttttcactgt
     3721 cagtcgtaat gtcacttcat ttggtttggc atatggtgcg atcgttggat tgatctgtgt
     3781 ctcaatcaga tcttttagct cagtgaccag tcgcgattca ccaatcccat aaaagcgcaa
     3841 aactttagaa attagttttt cttcagaagg aaaacgttcc tctagtaaag gacgtacttg
     3901 ttccacaaac attggtttca actcattagg cggaccggga agaaggatat acgcatgtgt
     3961 atctgtttga taaaaagtcc ctaaagcaag ccctgtacga tttggtagag gaaccccgcc
     4021 ttcgataatc tgggactgtt gcagattgtt tttggtcatt tttcgatggg ttgtttcaaa
     4081 atatgccaat aattttttgt atccttccgt attttgtatg agagacttac cgaggtgagc
     4141 cgcagttgct tcttttgtca ggtcatcttc tgtcggtcct aatccgccac ataagagtat
     4201 gagttcactt cttgtttcag ctagagcaat caactcttct aaacgctgct gattatctcc
     4261 tacaactgtt tgataataaa cttcgatacc tagatcagct agctgttctg acaagaaagt
     4321 ggcattcgta ttcacgactt gtcctagtaa aagttctgtt ccgacagcta ttatttctgc
     4381 tttcattact tcccgctccc ttatatagta tacgctgtat ttttatattt ttttatttaa
     4441 aaagagggca aggagctgtg acaaaaatct tgtcacagct ccttgttcca aataaacagt
     4501 gttctcctgc caaaacctcg gtcataagtc acaatataca taaaacatga aaagctgttt
     4561 tttgaaatta tcccttgtga ctcagagtta gacggcaggc tcacaacctc tccactaaac
     4621 gatacttaca ttgatccttt gaacacaccg ctgtttttga tgaagtaatc cacacctgaa
     4681 tagatagtaa agatcagaca agcataaagc atgatttgat ctactggaat accgatcagg
     4741 ctgaatggga tattattgat aaacagcaag ataatagcaa ccatttgtgt agccgtcttg
     4801 acttttcccg gccaagctgc agccatgact tctccatgtt cgacaagtag taaacgcaag
     4861 cctgtgacgg ctaattcacg acagacaatg atcgctacta cccaaccagg ggcctttcct
     4921 tggtcaacca acatgataaa agcagtcata actagcattt tatctgccaa cgggtccgca
     4981 aacttgccaa aattagtgac aaggcctcgc gcacgggcaa tttttccatc taaccagtct
     5041 gtgatactag ctaaagcaaa aataactgca cctactagct gtgtgacagc cagtgtggtg
     5101 tctcctacgt taaattgtcc ccaatctaaa ggtaaaccta caaccaaaat gaaaatcggg
     5161 atcatacaaa ttctaagtac agttaattta tttggtaaat tcacactatc gactcctttc
     5221 ttccctattc tacgtgacta tcagcgaagt ttccaccgat attatttact tttccaaatg
     5281 aatttattca aaggagtatt tttattgaaa ttgatctttt tgaattaacg aagaaggacc
     5341 gcgacacaga tttgtcacga tccttctttt ttatacctac aagtaaacag atgcgtaaac
     5401 taatttatac gatcattctg cgtattgaag agtaaggttc acattttttg gactctgatt
     5461 gttttcccct ggattaactg gtacggattc tccattcgct ttgatcgttg cattgcttgc
     5521 tgcaccaatc gtgatggtcg catttgttgc tgtttccggt aacacggtac tctgtgtttc
     5581 atttgctgcc agtgtccctt gataaacata ggcattgtct actagcacac ctaaccatac
     5641 acgattgaca gcagtaaatt caagggttac aggcttggta gcgtctgtga tatttactgc
     5701 gatggcactg ccagaatctt ctcctgtagc tattgccatt ttcttttctt cacttgattt
     5761 tgttgttgat tctactgtag aagactcttt ggtctgcgtg ctttgctctg aggaagagga
     5821 ctcctcgact gatccttcta ctttaagcga agaagctgtg tctccgatta ttggatcagc
     5881 ttgacgatct tgccaagtca tatagcccac gacaacgaca atcgccaaag caaccaatcc
     5941 taataaaatg acaggaagac ttgtccaaaa gcgacttgga tgcgattctt cctgatgcat
     6001 tgcttttcta gaagtactta ctgtttcagg ctgcggacgt tcagggaccg atcctgtcaa
     6061 tttgcttttc ccatcaaaaa catcgactaa atggtctcca tcttctccta cagcttcagc
     6121 gtattgccga ataaatgccc gcacgtaaaa tttaccaggc aattggtcaa aatcatcatt
     6181 gtcgattgct tccaaataac gtttttgaat ttttgtaatc tgctgtaatt catctaaaga
     6241 tattttttta ttcaggcgtg cttgccgtaa tttttctccg atggtttcaa aagccactcg
     6301 ttcatcttct ccagtctgtt tgattctccg aagcatctgc tgttgcaacg aaagacgtta
     6361 tgtttgggtg ctgtgacaaa agtcatgtca cagctccttt tttccgaata aacattgttc
     6421 tcctgccaac tcctcggtca caagtcacaa tatccaataa atataagaag ctgttttttg
     6481 aacttgttcc ttgtgactcg gagttaaacg gcaggctcac gacctctttc ttaaacggtg
     6541 ttcaatcagc tgttcctcgg tattagctca aaaaccggca aaatataagg agatattttt
     6601 ccgtatgttt ctctaatact caggtcaaaa cgctgatttc acaacctctt ccttaaacgg
     6661 tgttcaaaag cttgcatctg cggtaataag tccaaccaag ttaaaaacat taagaagctg
     6721 tttttacttg gctgttctta ttacttgatg cagggcagct ttttcacaac ctcttggtac
     6781 acggtgttcc agaagtagct tcttcggcaa taagccgaaa tatcacaaaa atttgagaag
     6841 caattttcgt aaattccttc ttatttcttg aagctgacca cttctgtcac aacctctttg
     6901 attacttcgt ttgattttat tttaatataa gttgattaaa agagagcatg atttgtttta
     6961 ttttctcact aatttttcca acacaactaa gaataccata aaagctgatt ttggaggagg
     7021 ttcctactac aagtctaaaa cgaaatttaa gacttttcct cataaaatac tggtttattt
     7081 tggtctcatg taaaactcgc tgaaggcctc ttcacttata aatgcttccc cagctgccag
     7141 tacgtctttc atttggatcg aatcgatgat ttcaggaaga tcaaataaag ttcgatcgcc
     7201 aaataaactt tgcgtaaatt gattggcaat atattcgatc gaatttaatg attggaaata
     7261 ttgtccaagc attttcttct tcagcaaatc gagatttgtt tctgacactt ccggatcatc
     7321 agcgaatcca agaatgattt ctttgacttt ttctgctgct ttctctggtt cgtccgtatc
     7381 tccgctgaag tccgcaaagt gaaattcacg atccaagctg aattcaaaac caaagctgtc
     7441 atcgataatt ccttgattgt acatcgctag atagtttcga gaagtattgc ctaaaatcat
     7501 ttggaacaac agattgattg ctgttttata gcgtaacagt tctgttcctt cttgcggcaa
     7561 tgtgtctaat cctttaatac caagtacaaa tttatctcgt gtaatggctg cttccaatgc
     7621 actttgtttg atgatttctt ttgtgttttc agggaaataa cgtacaattt cttgctttgg
     7681 agggaaattt tttgcttctt ggttttcccg aataagtttc atcaatttct caggctccat
     7741 cttaccaact acaaataaaa ccatattgct tggctgataa aacgtccgat agcacgtata
     7801 caagtcttga gctgtgattt tgtcgatact ttcaaccgtg cccgcaatat cgatatgcaa
     7861 tgggtgtgta ggatacaagt tatttagtat gccaaaaaac atccgccagt tagggtcgtc
     7921 ttcatacatt tggatttcct gaccgatgat tcctttttcc ttgtttacag tttcttctgt
     7981 gaagtaaggt gcttgtacaa aatcgatcag agtcgtcaga ttcttttcta cctgatccgt
     8041 cgtagaaaac agatagctgg ttttcgtaaa acttgtgaaa gcattggcgg aagctccttg
     8101 tttcccaaat aattgaaaga catcaccatc ttctttttca aacaacttat gttctaaaaa
     8161 atgggcaatt ccatctggaa ctttcacctt ttctttttca ccatagggaa taaattcgtt
     8221 atcgatcgaa ccataattcg tactgaacaa accatatgtc ttgtgatagt catttttagg
     8281 caacaaatac acggtcaaac cgtttggcag tacttcatga taaagtgttt cattgatttg
     8341 ctcatattct gttttattca tttgcatttc ctcctgctaa aaagaagatt gcctgcaatt
     8401 cgatttgctc agctacttgt tgtatctctt tgatcgttac gctctccata cgtttcaacc
     8461 attcttcatc agataatttt gtttccggca gccagctgtc caaaaaagaa gcttcgattg
     8521 ccgcttgcgg agagtctaga gaaagcagat attggtttct cagcattgct tttgtctgag
     8581 acagttccaa ctctgttatt tcaccatttc gcaaactttc taattgctcg tgaatcagat
     8641 gaagtacttg atttcggttc ttttcatcga taccggtttg gacactcatg aatcctcgga
     8701 acgtatccac gctactagag gcataataag ctagactttc tttctctctg acattcatga
     8761 aaagtttaga gtgaggaaaa ccgccaaata aaccgttaaa gaccattagc gcaaaacgtt
     8821 ctggttcatc gtaatacaca tttgtctgat aagctaggtt cagctttgct tgaacgattg
     8881 gctcacgtac ttgtcgttcc ttcacgatat tcacttgagg ttgggtataa aacagatctg
     8941 gataaactgt ttcccgcgac tcaaatggta attgcccaac tgcttcagct gctttgtccg
     9001 gatcaacatc gccgacaaca aaaatgtcga tttgatcatt tgccatcatt tcttgatagt
     9061 aggacgctag cgaactagca gtgatcttgt ccaaatcttc gactacgccc aaccctggga
     9121 tcttttgttc cgggctgttt tcaaaataaa gttcttgcaa ggcataggaa gcaaaagttt
     9181 gtttatcttc cttcaaactt tccaaatata gacgcagatt gttcttttcc aagtcaaacg
     9241 tcaactgatc aaactgatga tttttaatat ttggataaaa taaaacctct tttaaaaaat
     9301 ctaccgcttg agaaaaaagg tttggatcat tgacatattc accattcaca aaactgatcc
     9361 ctgcgtttag ccaatgtaaa tttccttttt ttctaactga taatccaaag cttgcgccat
     9421 aaagctctgc aagttgcgca cttaactttg tctgatccgg ataattcaaa ctatttgttt
     9481 ccaacatgct gctgagaagt gaacgtttcg tgatgacttc ttgttgcaga cgcgcagtaa
     9541 aacggataaa aatccggatc gttttgtatt gttttgttgg taagacatga agattcacgc
     9601 cttctgccaa ttgatacacc atatttatat gctccttttc acagttgatt gcccgcttac
     9661 tcttttaatg ggtcaacctg ccttttttac ttattcctct gcttgaaatt tataagttca
     9721 ggcaattcgc cgttttttct aaatgatgtt acactttata gtatagcata gatgtttttt
     9781 atcaaaagaa acagacggct aaaagcgtat attgtttttt tattttttat ttttcgatat
     9841 actaaagaca aataaaagaa gggagggtca ttcatgatca aagaattcaa agagttcatc
     9901 atgcgtggag atgtcttgga tcttgctgtc ggcgttgtta ttggtagtgc gtttacaagc
     9961 atcgtaaacc aagtggtgca aggcttgatc acaccactaa taggttggtt tgtcgcaatg
    10021 atcacaggta cttctgattt agaaggagca ctttcaattc ttgactggtc gccgacaaaa
    10081 ggcgtcacat ttgcgtttgg taacgttatt agtgctatca ttacatttct gatcactggt
    10141 tttgtcttat tcttagttgt caaagcggca aaccgtgcga agaatttacg ctccaaagaa
    10201 gagcaagtgg aagtggaaga aactcctact gcagaagatt atcttagtga catacgcgat
    10261 cttcttgcca aacaagtggc agaagacaat acacatccag tagagcaaac aaatctttcc
    10321 gatacttcta aataataaag aatctaaaaa aaagaaagcc gattttcagt gtcggctttc
    10381 tttttttaga ttcttaactt gctacttgtt cctttttcat gtcgatatgt ggaatatcat
    10441 cttccaaata cacatctgag attgccttga atccaaacga ctcataaaaa gcttgtaggt
    10501 attcttgtgc gccgatcacg attggttttt ctggaaaatt tttctggatc atgttaatcg
    10561 tttcttgaac aatctttctt cctaaaccat ctttacggtt gtcctgatga acaaggacac
    10621 gtccaaaatg gatactctcc gcttcttcat atactcgcgt gtaggcaagg atcttcccat
    10681 cagtatcttg aaaaaacgta tgccaagctt gtccatcaat gtcatcaact tcttgataag
    10741 gacactgttg ttccacaaca aaaactgcga ttcgttcttt gacgatcgcg taaaactctg
    10801 ctgttgacaa ttcttcaaat ttctttacct gatattccac taagcaaacg ccccctgctt
    10861 ttttattctt agcataccga ttcgcacaca aaaaagcaaa cgaaccttac gaatctcagg
    10921 ctcgtttgct ttttaaactg cttcagttaa aaattcgatc tcaactgtcc gagtaagtac
    10981 atctgaatag ctgtaagata ctcgttcaaa agaattttct tcaggatcca aatcaacaac
    11041 gaatactgaa ggataggttt ctgttaaaac gccgcggcgt tctgtttgac gctttcttcc
    11101 tgtctgagca accaacatga ttgggctgcc gatacgacct tctaaatctt tcttgattga
    11161 agctaaagtt gttggcatac agttcacctc tactatcaac tataccacat atttttaaaa
    11221 ttttcaagtt taccataaaa aaaaagaaat gcaataaaaa taaataagaa gctcattaag
    11281 atttttctaa attattcctc attataaaat ttcaagtgtt tttttatttt gagttttact
    11341 ctcccgtaag cgctcattac ttgcttgtga tccattgcta aacattcagc catgtctaca
    11401 aaatcaacgc cttgcatata ataatgaaaa attttagctt ctatttttga aaactggatt
    11461 tcgcaatttt cgattgcttc ttttaataaa agatgctgaa tcgctaaagg ttcttgcaat
    11521 gtgatctctg ctaaaaagtc tggtccttct gtctctattt tttggtcgat tgagacttca
    11581 tctttttgat cacgacgctt cagcgcgttc tgcttcctca acagagaata gatttgattg
    11641 cttataatgc ttttataata acttccaaag ctaacacctt tgcttttttc gtaagttctc
    11701 aatgcctgat ataaagcgat ccttgcttct tgttcccaat cctcagaaac ataatttctt
    11761 aaataatagg tgtttttcaa acgtagtaaa agtggaaaat atttttgata cagggcagca
    11821 aatgcttctt cgtcaccatt acgtgcagcg cgcaataact cctcagacat aaaataattc
    11881 ctccataaat tcgtttatgg aggaatctta tcatcaatga ttcatcgaac tgattagaac
    11941 gatatgttat ttattttttc tcattaaatc gtccaatttt tgggacaatt tttttaactg
    12001 ctcttcattc catggagaat tacgtcggaa atcaataaaa tgcatatctt tattttcttg
    12061 ggctattgtt ttttccgttt tttttatcgt cttatataat tcataagcag aagttcgtaa
    12121 tgctccttgg gaaaagatca tccactgttc tgctaaatcg cttgtcgcca ctgtcacttg
    12181 tgtcaaacgg tcattcagct gaccagcgat tctctcgata taactgtcag ccgtttcgtc
    12241 ttctttcgta aaaacaacat ccaactggta tttcttataa ttttgttgga tgcccggaac
    12301 tagttgggca tcgaagacaa cgatgacttc cattccttca tatttcgcat aatttgataa
    12361 acgatgtaaa agagcttctc ttgcatccgc cattttgtcc tgctttttaa gctggacaag
    12421 ttccggccac gaaccaatca tgttgtagcc gtctacaatc aacagctgtt ttttcatggt
    12481 ctactccccc tgacgttggg aaaaagcctg atacataagc aaaccagcag caacactggc
    12541 atttaagctc tggacgtgcc cggtcatcgg gatcgtcagc aattcatcca tttctttttt
    12601 caatcctgga ctcattcctt tgccttcatt accaatgact aaagcaattg atcctttggc
    12661 attccatttt tggaagtttg tgccggtcat atctgtgcca aatacccaaa atcctgtttc
    12721 tttgagctgt tgcacagctt gtaccaaatt cgtcacgcgt gcaacaggga catgttcgac
    12781 tgccccagtg gaagtctttg ttacgatagg tgtgattcca actgctcggt gttttggtat
    12841 gatcacacca tcgacgccac ttgcgtctgc tgtccgtaaa atcgacccaa aattgtgtgg
    12901 atcttcgatg ctatccaaaa tcaaaaagaa ggggtcttct tttttctctt ttgttcgttc
    12961 aatcagttgg tcaagggata aatattcata aggtgtaatc gcaagaacga ctccttgatg
    13021 cacgccgtga tcgctcaaag tttctaattt ttgtttagga acccatttga ctggcacagc
    13081 ttgttcacgt gcgatttctt tcagttcttc tactttttct cctcgtgaat cttcttgaag
    13141 aaagagttta ttccctcgcc cttgttgtag cgcttctact gcggcatggt gcccaaagac
    13201 gaaattatct tctaatgctt cttcattttg atcagaaact gactgatttc gtccagtttg
    13261 ctttttattt gaatatctat tttgtttttt gtcttcaaat ccacgtttcg attgatgttt
    13321 gtttgttctt tctttaccca tttttttcac caactttctg aatacaccag cggatcaatt
    13381 cttccatccg ctcggtttgt tttgtcaaat gcagatagcc catgagcgct tcgaaccctg
    13441 ttgcgacccg atacgtcgta acatcagcat tttttgcgct cgtatggctt ttagcatttc
    13501 ttcctctgcg ataataaagt tcttcttctt ctgtcaaaag atgttcttcc agcatttgct
    13561 gaatcaaaaa ggcttgtgca ttcgcagaaa cataattcgt tgccgcacga tgcagcttat
    13621 tgggttttgt ttctccttga tcaatcaggt ggtcacgaac atagatttcg taaatcgcat
    13681 ctccaacata agccaaggct aaaccgttca attgtgtgta atctctcatg cttctcttct
    13741 ccatcgggtt ccttgcggtg tatcttctaa taagatccct ttttctttca acaaatcacg
    13801 aatttcgtcg cttcggacaa aatcacgatt gcttcttgct tgatttcgtt cttcgatcaa
    13861 ttgttcaatc tcttcatcta ataactcttc tgctgtaaat aaaataccga agatcgaaag
    13921 ccattgcgag aataaagctt ctccttgtgc caagacagcg gcagaaactt tcggctggtc
    13981 tagataagtg ttcagccact tagcaagctc atagaccact gtgatcccat ttgctgcatt
    14041 aaaatcatcg tccatttctt cgatgaatcg ctgttctaaa ttttctaaca aagcgatttt
    14101 atccgcatca tctgccaaat tctctgaggc agtttcttgg cggaatttca aattgtcaaa
    14161 cgtattcttc agtcgttgta aattggtggc tgcttctttc atcgtcgttt cactgtagcg
    14221 gatcggacga cggtattgtg tggtcgccat gaagaaacgc aagacttgtg gatcaacgtt
    14281 tttgatcatt tcatgtacag tgatgaaatt ccctagagat ttactcattt tttcatcgtc
    14341 ttcgccaatc gttacatagc cattgtgcat ccagtaatta gcgaattttt tccctgtttt
    14401 cgcttcactt tgtgcgattt cattttcatg atgaggaaat tctaaatctt gcccgccacc
    14461 atggatatcg atcgtttctc ctaaatgttt tgttgccata acggaacatt caatatgcca
    14521 accgggacgt cctttgcccc atggtgaatc ccaagaaatc tcgccaggtt ttgcttgttt
    14581 ccataaagcg aaatctaatg ggtcttcttt ttgctgctgt tcttcccctg tacgctgact
    14641 tgctccgact tccagttcat cgatggattg gtcacttaat ttcccataat tttcaaattt
    14701 acgggtacgg taatacacat cacctgaaga ttcataagca tagccttttt caaccaacac
    14761 ttgaataaat gctaaaatat ctggcatatg atccatgact cttggatgca gtgtagcagg
    14821 ctcgacattc aacgctttcg tatcttcttc aaatgctcgg atgaaacgat cagcaacttc
    14881 tggtgctgta atacctaatt cgtttgctgt acggatgatt ttatcgtcta catccgtgaa
    14941 attcgatacg aaatcgactt tatagcctcg atattcaaaa tagcgtcgaa ttgtatcgaa
    15001 agcaatggtg ctacgagcat ttccgatatg gatataatta tacacagtcg gtccgcagac
    15061 atacataccg acatgtccct tttgtatagg gatgaattct tctttttttc tggtcaatgt
    15121 attgtagatt tttatcattc tgatctcctc actttttctc ctttgattcg aacgactttt
    15181 gctggtactc ctaccgctgt agcgtcgtct ggaacatctt tcaacacaac ggcacctgca
    15241 ccgattttgg cgttttttcc gatcgttacc ggtcctaata tctgcgcatt cgcagagagc
    15301 atggctcctt gtttaacagt tgggtgtctt ttacccgttt cttttcctgt gccgcctaat
    15361 gttacgccat ggaataaaat cacatcgtcc tcgatttctg cggtttcgcc aatgacgatt
    15421 cccattccat ggtcgatgaa cacgccagtt ccaatcgttg ctcctggatg gatctcaaca
    15481 ccagttagga aacgccagaa ttgagcattg atcttcgcca ataaaaagag ccggtgctga
    15541 tataaaaaat gagagaaacg atgccaaaac aaggcatgaa aaccagggta tgtcaaaacg
    15601 atctcagctg tcgaacgtgc agccggatcg tttctctttg ctgcatcaat cgctcgggta
    15661 aaccaactca tgactttcca ctcctttcgt aagaatttta tgtaggaaat catcttctta
    15721 taaagaaaag aagcgccttt taaataagtt tccttatcaa aagacgcttt ccgcgtggtt
    15781 ccacttttct tcataatcaa tgattatctc tgacagctaa cgcctgttat acgttcttgg
    15841 ctactttgtt tcctataaaa cagtttttcc tgttttctgt gtttcgccaa gaccactccc
    15901 agaggcattt cggcaaccat tcattgatac cttgcaccac ccggtatctc tcttgtaatg
    15961 atcagctgct tacttttttc tgttcatcgt gtttagttca gtacttgatt taaatgtgct
    16021 aatgattttt cacgaccaag caattcgatc gtttcaggca attctggacc atgcatttgt
    16081 cctgatacag ctacacggat tggcatgaaa agattttttc cttttacgcc agtttctttt
    16141 tgaacagctt tgatggcagc tttgacagtt ggagcatcta ctacttccat ttgttctagc
    16201 tgtgctttga atgcgtggag aacagtagga actgtttcac cagcaagtac ttcttttgct
    16261 gcttcattca atacaggatg ttcattgaaa aatagcgtag acagatcaac gatttctgca
    16321 gcatagctca tttgaggttg atacaggcta acgatcttct tcacccattc gattgtcttt
    16381 tcatctgggt tttctgctac acgtccatca gcgattagat aaggcagaca catgtcagta
    16441 aatgcatcta gatccattgc tttgatgtaa tggttgttta cccattgcag ttttttcgca
    16501 tcgaaagctg cgggtgattt acttaggcgt tttggatcga acattttgat caattcttgg
    16561 tgttcgaaga tttcgtcttc gcccacaggt gaccagccca ataatgcaat aaagttgaac
    16621 attgcatctg gtagatagcc taattcgcga tattgttcga taaattgcaa gattgattcg
    16681 tcacgtttgc ttagtttttt acctgtttca ctgttgatga tcaatgtcat atgtccgaag
    16741 gttggtggtg tccagccaaa tgcttcatag atcatcagtt gttttggtgt attggcaata
    16801 tggtcatctc cacgtaaaac gtgagtgatt ttcatcaaat gatcatcgac cgcaacagca
    16861 aaattataag ttggcatacc atcgcgtttt tgtatgacaa agtcgccacc gatattatcg
    16921 gattcgaacg aaatagcgcc tttcaccata tctgtaaatg cgtattctgt attgcgaggc
    16981 acacggaaac gtacaacaga ttctagacct tgtgcttctt tttctgcttg ttcttcaggt
    17041 gtcaagttcg cacatgttcc tgcgtaatga ggcatttctc ctcttgcgcg ttgtgcttcc
    17101 cgttctgctt ctaattcttc ttctgtgcaa tagcatttgt atgctcgatt gctagcaagc
    17161 agctgatcaa tcagcggttg atagatttct ttacgttcag attgacggta agggccgtat
    17221 tctccaggat tttcaggaga ttcatcccaa ttcattccca accaagcaag gttttccaac
    17281 tggctttttt cgccatcttc gatattacgt ttttggtcag tatcctcaat acgaataata
    17341 aagtctccat cattgtggcg ggcaaacaaa taattgaata atgcagttct tgcatttcca
    17401 atatgcaggt gcccagttgg acttggtgca tagcgtacgc gtactttcgt cattttcttc
    17461 ctcttctttc aaactagact ttgactaaca gcaaaaattc cgtcagttac ggcttctcaa
    17521 atatcattta tttaaagcca ctcagcacaa attttacctt ttctaaggta aatagtaaag
    17581 ccaactggtt gaatttcctt accagttggc tgaatttctt ttttattttg attgtttagt
    17641 ctttttctct gtctcttttt tattgtcgat tcctcgtcct gcatgtgcag gtttagcaaa
    17701 gatcatgcgt ccagcagctg tttgaagggc acttgttaca acgacttcga tacgttcatt
    17761 catgtaatgc tgtccatctt ctacgacaac catcgtgccg tcatcaaggt aggctactcc
    17821 ttgttggcgt tctgtcccgg cttttactac tagaacattc atcgtttcac cagggatgac
    17881 gactggtttt acggcatttg ccaacgcatt gatattaaga acaggtacat tttggaattc
    17941 agagacttta ttcaagttat agtcattggt tacaatgaca ccatctaaaa gcttagccaa
    18001 tttgatcaat ttgctgtcta cttcactgat atcttcaaag tctccatcgt acatttcgac
    18061 agatataccc tcttcttttt gcaaggcatt taggatatct aatccgcgac gaccacgcac
    18121 acgtttcaaa ctatcccctg agtccgcgat gtattgtagt tcgtaaagaa caaaattagg
    18181 gatcatcaag gttccttcta agaatccagt ctttgtaata tcataaatcc gaccgtcaat
    18241 gatcacgctt gtatccaaga ttttatattt atggaaattt tctcctgatt ttcgttctaa
    18301 cagttgactc tcaacttgac tagctgtttc ttgctcgatt tttttgcttc gtgaaccaaa
    18361 aactttcttc cattcttcga ttcgtgtcgt tcccattctc aatcccagat agcctaagat
    18421 gatcatcagt aaaatcggca atacactatt gacgaatgga atttccatat tgtaaagagg
    18481 ggtcgagatc acaacaccta aagtcaatcc gatgatcgca ccgatcgcac cgaagagaag
    18541 ataagtcaag ctgacctcac ttagtttttg ttctacttgt ttgataatag ctgagatatg
    18601 tttggccaac agcaaagata ataaaaagaa aataagtgcg cctaacaggc tgttggtaaa
    18661 tgtattattc agccatccgt ttgactgttg accgattgcc tgccaagctg agggtaaaaa
    18721 tgaaataccc aagcttgcgc cgacaatgat catcagcaaa gtaatgacac gtttttgcat
    18781 cgtttttcct ccgtttcgac aatcatttat tagttagcgg aacacacgct tcaacgtttc
    18841 agccaaagtt gctactccaa ctatctcgat tccttttggc gcttcccagt tacctaagtt
    18901 gtttttaggt aggtatactt ttgtgaagcc gagtttttgg acttctttga ctcgttgttc
    18961 aatatgactg acacgtctga tttctccagt cagtccaatt tcaccgatga aacattccgt
    19021 tggctgtgtt cctttttctt tatagcttga agcaatactg acagcgatag ctaaatcaat
    19081 cgctggttca tttaatttta ccccacctgc agcttttaag taagcatctt gattctgaag
    19141 aagcaaccca gctctttttt ccagcactgc catgatcaga gatacccgat tgaaatcaag
    19201 acctgttgtt gttcgtttgg catttccgaa catagtaggt gtgactaatg cttggatctc
    19261 taccaaaatt ggacgtgtcc cttccattgc cacaacgata gcagagccag ttgcaccgtc
    19321 taggcgttct tctaagaaaa tctgtgaagg attagcgact tcttccaatc catgctcatg
    19381 catttcaaaa atcccaatct cattcgttga gccaaatcgg ttttttactg ctcgcaaaat
    19441 ccgaaaacta tgatgttgtt caccttcaaa atataacacc gtatccacca tatgttctaa
    19501 cattcttggg ccggcgatcg agccttcttt ggtaacatga ccgacgataa aaatggctat
    19561 cccatttgtt ttagcgattt tgagtagttc tgcagtggtt tctcttactt ggctgacact
    19621 tcctgccaca cttgtgatgt ctggctgcgt catcgtttgg atggaatcaa tgataacata
    19681 atcaggggag atatgttcga tggcacgact gatttcgttc atatctgttt cagcgtatag
    19741 ataaaattct gtgttgatac ttccgaggcg ttccgcgcgt aattttatct gctctgcgct
    19801 ttcttcgccg gatacatata agacttttcc gcctatggct gctaattgct gagaaacttg
    19861 taacagcaaa gtggatttcc cgatacctgg atcgccacca atcaagacca tagaccctgg
    19921 caccacacct ccgcctaaca cacggttcag ttcttctaat tttgttttga tccgaggttc
    19981 ttttttaggg acgacgtctg cgatttttgt tggttttgct ttttctcctg tcaaacttgt
    20041 ccgagttctg cggtccgttg tatcttgttc gatttcttcg accatcgtat tccattttcc
    20101 gcaatttggg cagcgtccca agaacttagg cgacacatac ccgcaatttt ggcaaacaaa
    20161 ttgtactttt gatttttttg ccattgtacc gcctcctttt atcctaatca tgagacatta
    20221 aatcaagctt aagtatcttt aacgttttat ttactggaag aaccaaatcc gccttgacgt
    20281 tgagcagtcg tttgatcttg atctgctttt aaaaacggca aaaagatccc ttggccgata
    20341 cgctcgcctt ttttgatcac tacatccttg aaaccaaagt tggtgaattg gaacatgata
    20401 tggccttcat ttgcctcatt attgtaataa tcactgtcaa tcacacctac tccgtttgtc
    20461 aacactaaaa accgcttcaa cggattgctt gaacggttag caagctgcaa aaattcatct
    20521 tctcccatgt aagctttgat tccagtaggc acgagggttg gtttcaattg tttttcattt
    20581 tctgatacat cttttttcaa tccatctgcg actgtttcca accccttttt ccagcctgct
    20641 ttccagatac ttggaatcac gacctcttct gctgcttcaa aatcatagcc agcagcatga
    20701 tgtgtagcgc gctgcggtag attgatattt tgatctttat atttagaaat aacttcaaat
    20761 cctctttttc tcaccggttt tcct
//
LOCUS       DAFBVQ010000049        20545 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.051, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000049 DAFBVQ010000000
VERSION     DAFBVQ010000049.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20545)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20545)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20545
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.051"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(130..849)
                     /locus_tag="LLC22_002001"
     CDS             complement(130..849)
                     /locus_tag="LLC22_002001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YebC/PmpR family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5435260.1"
                     /translation="MGRKWANIVAKKTAKDANNSRIYAKFGIEIYAAAKSGDPDPHAN
                     QKLRFVIDRAKTYNVPKHIIDRAIEKAKGAGDETYSELRYEGFGPSGSMVIVDTLTNN
                     VNRTAADVRAAFGKNGGNMGVSGAVSYMFDNTAIFAFAGEDADEILEYLMEKDIDVRD
                     VMEEEGQIIVYGEVADFHSIQEALKEKGITDFSIAEIQMIPQNEVTLSPEDQETFEKM
                     IDALEDLEDVQHVFHNVALED"
     gene            complement(980..2131)
                     /locus_tag="LLC22_002002"
     CDS             complement(980..2131)
                     /locus_tag="LLC22_002002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298249.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase"
                     /protein_id="HBK5435261.1"
                     /translation="MKSCGIIVEYNPFHNGHRYHVEMARKITGAEVVIAVMSGNFLQR
                     GEPAIIDKWHRANEALQNGVDLVVELPVEWAVQSADYFAKGAVKILQTLDCDSLCFGT
                     EEETSFDYSSFGRFVQENQDRIEEAFQELSDQTYSYPQKMTEVFRSLYPDITLDFSSP
                     NHILGLSYAKENAKYVHPMELHPIRRKSAGYHEKIITDQRIASATAIRHALEEGKRIA
                     GLVPPQTEEDLSTCSLQTWESYWPYLRYRLLSSTLLELTDIYQMTEGIESRMKTAAAT
                     ADSFEDFVSKVKTKRYTWTRIQRLSCYVLLNIKKQEIPVQQNKNYLRLLGFTDAGRRF
                     LKEKKEISIYSRIGKKEAQEAELLVRSDQIYQLGGNIPEQNFGQIPIRV"
     gene            complement(2348..3088)
                     /locus_tag="LLC22_002003"
     CDS             complement(2348..3088)
                     /locus_tag="LLC22_002003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339667.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5435262.1"
                     /translation="MAYETFAFIYDEVMDETLYQQWLAFSKRHLQEDTKNILELACGT
                     GALAVAFAKDGYKVTGLDLSEEMLMIASQRAYEEDASIQFVEGNMLDLSEIGQYQAIT
                     CFSDSLCYMKNRQEVQQVFDEVYQALEENGRFLFDVHSTYQVDEVFPEYSYHYQGDNF
                     AFLWDSYPGSEKHSIEHFLTFFVEEQEGSGRFIREDELHQERTYPLESYLRMLENSGF
                     SKVEAFSDFTDEAASEKSKRWFFVAYKD"
     gene            complement(3092..3415)
                     /gene="rsfS"
                     /locus_tag="LLC22_002004"
     CDS             complement(3092..3415)
                     /gene="rsfS"
                     /locus_tag="LLC22_002004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome silencing factor"
                     /protein_id="HBK5435263.1"
                     /translation="MEAADSKRAEDIIALDVRNVSLLADYFMICSANSERQINAITEE
                     IIDKEEENKYEVKRIEGKEGGKWVLIDLGDVIVHVFHAPERNFYNLEKLWSDAPLVDL
                     SEWLD"
     gene            complement(3472..4065)
                     /gene="yqeK"
                     /locus_tag="LLC22_002005"
     CDS             complement(3472..4065)
                     /gene="yqeK"
                     /locus_tag="LLC22_002005"
                     /EC_number="3.6.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326076.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bis(5'-nucleosyl)-tetraphosphatase (symmetrical)
                     YqeK"
                     /protein_id="HBK5435264.1"
                     /translation="MNMDYSNEYTAYSRENLMQKIQMRMSEQRFKHVLGVEETAVALA
                     KKYGASPEKASIAALTHDYAKERPDEEFKMVIVRDGFDPELLNYNNAIWHGLVGASFV
                     ERELGITDAEILHAIRVHTTGAAKMSLLDKIIYVADYIEPGRDFPGVQDARAIAWADL
                     DEAVAFETKHTLAHLLAQEQQIYPKTIETYNYWVAKK"
     gene            complement(4049..4699)
                     /locus_tag="LLC22_002006"
     CDS             complement(4049..4699)
                     /locus_tag="LLC22_002006"
                     /EC_number="2.7.7.18"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nicotinate-nucleotide adenylyltransferase"
                     /protein_id="HBK5435265.1"
                     /translation="MMNTQAKTFVRSQLFPEEMPQFLEKKKQVGILGGTFNPVHLAHL
                     VMAEQAGRNLGLDRVFLMPSYQPPHVDEKQTIDAKHRLNMLELAVEDNPFLQIETIEL
                     ARGGKSYTYDTMKELTQNNPDTDYYFIIGGDMVEYLPKWYKIDELTSMVNFVGIRRPG
                     YTTDTPYPVIWVDVPEIDISSTKIRQKIKEGCSIRYLVPDKVIDYIQNEGLYEYGL"
     gene            complement(4709..5020)
                     /gene="yhbY"
                     /locus_tag="LLC22_002007"
     CDS             complement(4709..5020)
                     /gene="yhbY"
                     /locus_tag="LLC22_002007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome assembly RNA-binding protein YhbY"
                     /protein_id="HBK5435266.1"
                     /translation="MSLRGKQKRFLRSKAHHLQPIFQIGKGGINSAMIVQIEEALEKR
                     ELIKVSLLQNTDEIAEEAAQVLEKEIDCEIVQIIGRVIVLYKPSTKEKYQRLSKEVKA
                     I"
     gene            complement(5036..6145)
                     /gene="yqeH"
                     /locus_tag="LLC22_002008"
     CDS             complement(5036..6145)
                     /gene="yqeH"
                     /locus_tag="LLC22_002008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002370701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase YqeH"
                     /protein_id="HBK5435267.1"
                     /translation="MTEELQCIGCGAVIQTNKPGELGYTPQTALEKGLASGEVYCQRC
                     FRLRHYNETQDVSLTDDDFLRLLNELGQKDALIVNVVDIFDFNGSLIPGLHRFVGDNP
                     VLLVGNKVDILPKSLKKTKLTQWMKERAYEAGIRPVDVLLTSAKKSHEMTELLEKIEE
                     YRDGRDVYIVGVTNVGKSTLINQIIKNTAGVQDVITTSQFPGTTLDKIEIPLDDGHFL
                     IDTPGIIHRHQMAHYLGKKDLRIIAPLKEIKPKVYQLNEGQTLFLGGLARFDFISGNR
                     ASFIAYVSNDVNIHRTKLEKADEFYQKHVGGLLQPPRPDEVEAFPELVRFEFSVKEKT
                     DIVFAGLGWITVTAPVVIAGWAPKGVDVLKRKALI"
     gene            complement(6142..6669)
                     /locus_tag="LLC22_002009"
     CDS             complement(6142..6669)
                     /locus_tag="LLC22_002009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YqeG family HAD IIIA-type phosphatase"
                     /protein_id="HBK5435268.1"
                     /translation="MFSNYKPTWMVEAIYQITPAQLKNLGIKAVLTDLDNTLIAWNNP
                     DGTEELLTWILEMKNAGIPVVVVSNNNSKRVARAIEKFDLLYVARAMKPLARGINIAK
                     KQLDLADDEIVMVGDQIMTDIRGANRAGIRSILVKPIIATDSWKTQFNRFWEKRIMAY
                     LLAKHPDMGWRGGIE"
     gene            complement(6849..7634)
                     /locus_tag="LLC22_002010"
     CDS             complement(6849..7634)
                     /locus_tag="LLC22_002010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343529.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyl transferase
                     subunit alpha"
                     /protein_id="HBK5435269.1"
                     /translation="MDKTAHDVVQLARAKERWTSLDFFEEIFDSFEECHGDRLFADDE
                     AIVGGIARLDGKPVTVIGIQKGRDLQENIRRNFGSPHPEGYRKALRLMKQAEKFNRPV
                     ITLINTAGAYCGVGAEERGEGEAIARNLLEMSDLKVPIIAIIIGEGGSGGALALGLAD
                     EVWMLEETIYAVLSPEGFASILWKDGSRAAEAAELMKITAPELRELGIVDRVIPETFN
                     GEQLPRYKVAHIMKKALIERLTELVRLDQHKLLEKRYKRFRQY"
     gene            complement(7627..8496)
                     /locus_tag="LLC22_002011"
     CDS             complement(7627..8496)
                     /locus_tag="LLC22_002011"
                     /EC_number="6.4.1.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase carboxyltransferase
                     subunit beta"
                     /protein_id="HBK5435270.1"
                     /translation="MALFKKKKYIRINPNRESKPANSPSVPDNMWAKCPNCKHILYTK
                     DIGEEKVCPHCGYAFRIGAWQRLALIIDEKSFEEWDTDLVTKDPLAFPEYTEKIKKMQ
                     DKTGLHEAVLTGKATIQGIPFIIGVMDPNFIMGSMGTIVGEKITRLFERATKESLPVV
                     LFTASGGARMQEGIFSLMQMAKISAAVKRHSNEGLFYLTVLTDPTTGGVTASFAMEGD
                     IILAEPQSLIGFAGRRVIEQTIKQELPEDFQKAEFLLSHGFVDQIVPRMELKQKIHTL
                     LELHTQKGWIDRG"
     gene            complement(8497..9876)
                     /locus_tag="LLC22_002012"
     CDS             complement(8497..9876)
                     /locus_tag="LLC22_002012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629454.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxylase
                     subunit"
                     /protein_id="HBK5435271.1"
                     /translation="MFSKVLIANRGEIAVRIIRACRELGIQTVAIYSEADAEALHTQL
                     ADEAICIGPAKAVDSYLNVQEVLSAAIVTKAEAIHPGFGFLSENSRFASMCEECNITF
                     IGPKSATIDAMGNKINARQLMQEANVPVIPGSTGVLSTVEEALEIADRIGYPVMLKAA
                     AGGGGKGIRKVQSKEELPQHFSSAQQEAAAAFGNDDMYLEKIIYPARHIEVQILGDRF
                     GHVIHLGERDCSLQRNNQKVLEESPSVVISQTKREALGDAAVRAAKAVNYENAGTIEF
                     LMDEEGDFYFMEMNTRIQVEHPVTEMVTGIDLVKKQVEIAAGEPLNVCQEEVVFQGHA
                     IECRINAENPAFHFAPSPGKIQNLLLPAGGMGLRVDSAVYPGYTIPPYYDSMIAKIIV
                     HGNTRFEALMKMQRALSEFITEGIITNAEFQMDLISHPAVIAGDYSTAFLQEEFLPNW
                     TPETEIGGA"
     gene            complement(9884..10303)
                     /gene="fabZ"
                     /locus_tag="LLC22_002013"
     CDS             complement(9884..10303)
                     /gene="fabZ"
                     /locus_tag="LLC22_002013"
                     /EC_number="4.2.1.59"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723308.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-hydroxyacyl-ACP dehydratase FabZ"
                     /protein_id="HBK5435272.1"
                     /translation="MNIQEIKEIIPHRYPMLLIDRVEEMVEGERIVAKKNVTINEPFF
                     QGHFPEEPVMPGVLIVEAMAQAGAVALLSLEQFKGKTAYFGGLDKAKFRKKVTPGDTL
                     YLEVEILKVKASAGIGKGIAKVDGKKVAEAELTFMIG"
     gene            complement(10328..10804)
                     /gene="accB"
                     /locus_tag="LLC22_002014"
     CDS             complement(10328..10804)
                     /gene="accB"
                     /locus_tag="LLC22_002014"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302926.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyl-CoA carboxylase biotin carboxyl carrier
                     protein"
                     /protein_id="HBK5435273.1"
                     /translation="MDINEIRELVSQFDQSSLTEFDLREGQFELYMNKNKTSRGMNMV
                     QTNETLPVSEPVNVIPEQATTAPEIMKEKESAVFDGIEVVSPIVGIVYLQPAPDKPAF
                     KKVGDQVAKGEVICIIEAMKLMNEITSEADGVITEILVENESVVEYGQPLFRIQQK"
     gene            complement(10807..12042)
                     /gene="fabF"
                     /locus_tag="LLC22_002015"
     CDS             complement(10807..12042)
                     /gene="fabF"
                     /locus_tag="LLC22_002015"
                     /EC_number="2.3.1.179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-ketoacyl-ACP synthase II"
                     /protein_id="HBK5435274.1"
                     /translation="MNRVVITGYGVTSPIGNDADSFLNSLKEGTNGIAPITKFDASET
                     GITLAGEVKDFPYDKYFIKKDSKRMDMFSIYGIYAALEAMEMSGLDKEKMNQDRFGVI
                     IGSGIGGLPTIENQVIRLHEKGAKRVSPMFVPMAIANMAAGNIALRVGAKGICTAIVT
                     ACASGTNSIGEAFRNIKHGYSDVILAGGTEATICEMGIAGFAALTALSESTDPNRGSI
                     PFDENRNGFVMGEGAGVLVLESLEHAQARGAKIYGEIVGYGANCDAYHMTAPTPDGSG
                     ASKAMKLAMEEAGVQPEQVGYINAHGTSTPANDQAEAKAIQIALGENFRDTYVSSTKS
                     MTGHLLGAAGGIEALATLLALEHQFIPPTINVEKQDPEIDLTVVKNESKPASFTYAMS
                     NSLGFGGHNAVLCMKRWEE"
     gene            complement(12061..12798)
                     /gene="fabG"
                     /locus_tag="LLC22_002016"
     CDS             complement(12061..12798)
                     /gene="fabG"
                     /locus_tag="LLC22_002016"
                     /EC_number="1.1.1.100"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-oxoacyl-[acyl-carrier-protein] reductase"
                     /protein_id="HBK5435275.1"
                     /translation="MDVKGKNVFITGSTRGIGKAMALAFAKAGANIILNGRGEIPKEK
                     IEEIEAFGVKCVGVSGDISDYEKAGQMIKEAEEKLGSIHVLVNNAGITNDKLVMRMDA
                     EDFKKCLDINLIGTFNMTQHVLKKMMKQREGAIINLSSVSGLIGNIGQANYAASKAGV
                     VGLTKSVAREAATRGITCNAIAPGFITTDMTEVLADKVKEQAEKQIPMQRFGQVEDIA
                     QTAVFLAQNPYITGQVINVDGGLVMHG"
     gene            complement(12810..13727)
                     /gene="fabD"
                     /locus_tag="LLC22_002017"
     CDS             complement(12810..13727)
                     /gene="fabD"
                     /locus_tag="LLC22_002017"
                     /EC_number="2.3.1.39"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ACP S-malonyltransferase"
                     /protein_id="HBK5435276.1"
                     /translation="MKTAFLFSGQGAQYQGMGKDLYEEAVVKQTFDEASEILGYDMAE
                     LCFTENERLDQTQYTQPAILTVSIAYYRLLKEHGIIPDAALGLSLGEYSALVASNALS
                     FTEAVALVAKRGAYMTEAAPAGSGKMVAVMNAPIETIEESCHEASKYGIVSPANYNTP
                     QQIVIGGEEKAVDEAVLLLKEKGFKRMIPLNVSGPFHTAILEPAAKKLAKDLSQIQFS
                     EPSFPIISNTTTEIMKKETIAGLLEQQVMQPVRFYESIHKLKTIGIEQVIEVGPGKVL
                     SGFMKKIDKTIPVLRVENKQTFDETIAIL"
     gene            complement(13834..14058)
                     /locus_tag="LLC22_002018"
     CDS             complement(13834..14058)
                     /locus_tag="LLC22_002018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl carrier protein"
                     /protein_id="HBK5435277.1"
                     /translation="MVFEKIQEIIAEELGKETEEIKLTTDIQEDLEADSLDLFQIINE
                     IEDEFDVKIETEDGIKTVQDLVTYVEKQTA"
     gene            complement(14111..15073)
                     /locus_tag="LLC22_002019"
     CDS             complement(14111..15073)
                     /locus_tag="LLC22_002019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738756.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ketoacyl-ACP synthase III"
                     /protein_id="HBK5435278.1"
                     /translation="MEQFGMITATASVLPEKIITNNDLSKMMDTSDEWISSRTGIRER
                     RCVTNQETSDLCILVAEKLIKQKNLNPKDLDFILVATMSPDYTTPSVAAQVQGKLGAT
                     HAIAFDISAACSGFVYALSMAEKMIRCGSTKGLVIGGETLSKLIDWSDRTTAVLFGDG
                     AGGILLEANPQKKLLKEKLAADGTRSSSLTAGYQQNKNPFYSEDSEGSYYLQMTGRDI
                     FDFAVRDVANNIQEVMKDKPVDYLLLHQANLRIIEKIARKVKMPQEKFLTNMDKYGNT
                     SAASIPILLDEAVSSGKITLGKQQKVIFTGYGGGLTWGSILMEL"
     gene            complement(15083..15523)
                     /locus_tag="LLC22_002020"
     CDS             complement(15083..15523)
                     /locus_tag="LLC22_002020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005471259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5435279.1"
                     /translation="MEPDLKTVNDYLVSVFNDILTIEESELKKSQFKDLSITEMHTIE
                     AIGMYKKKTTSEVAKELSITVGTLTTAINKLVKKGYVERIRSEDDRRVVKLGLTKKGK
                     LLFRVHQHFHREMVKNILDGMATEEQHALLDALKNLHDFLQDYK"
     gene            15829..16794
                     /locus_tag="LLC22_002021"
     CDS             15829..16794
                     /locus_tag="LLC22_002021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GIY-YIG nuclease family protein"
                     /protein_id="HBK5435280.1"
                     /translation="MLKEKMKTLPMLPGVYLMKDRDGKVIYVGKAKRLKNRVSSYFHQ
                     NKQHSKKVLRMIHHITDFDFVVVDTELDALLLECQLIQHYRPFYNRQMNYFSNYNYVH
                     ITNKGFVLTDTPTARTYGPFRLYKKMPSILRIMEETYQMPWLSEISLLALRVQLPDLQ
                     EMTFEQKKKELQGLFQGRNKKLLTYLKKRQQHFIYQLNFEKAGMLQKDIELVTYFIRR
                     IQEQKQFLRTPSLTFSMPLAADESQKKHYLVCYGQLAETMITSGDVSPDFYYEKKEAH
                     LSLKRQLSKEEIDPVQILISYRKKLEKEQFEIELLNKKEAEKQLN"
     gene            complement(16851..17081)
                     /locus_tag="LLC22_002022"
     CDS             complement(16851..17081)
                     /locus_tag="LLC22_002022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YkuJ family protein"
                     /protein_id="HBK5435281.1"
                     /translation="MTHSQLVAIIKRLEAMVESADNELQVRRFEKEGVEKCTVTYDKA
                     TDTFELTETDTHQQYEFDNIDIVAMEIYDLIQ"
     gene            complement(17167..18054)
                     /locus_tag="LLC22_002023"
     CDS             complement(17167..18054)
                     /locus_tag="LLC22_002023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)-dependent oxidoreductase"
                     /protein_id="HBK5435282.1"
                     /translation="MKLGFIGTGVMGSAVARHLLEAGHEVAVYNRTKAKADPLVTEGA
                     IWADTPKAVAEQSNILFTMVGYPKDVEEIYYGQSGIFSADISGHILVDLTTSTPSLAE
                     KIAKTAKEKGADALDAPVSGGDLGAKNGTLTIMVGGEEAVYDQVLPLFKEFGTTFTLH
                     GSAGKGQHTKMANQIMIAGTMTGMTEMLVYAQKNGLDLKKVIETLSGGSAANWSLSNY
                     SPRILKEDYTPGFFVKHFIKDLKIALEEAEKMDLVLPATTQALKLYEELADKGFENDG
                     TQALIKLWWPEGKIPEKKS"
     gene            complement(18143..19366)
                     /locus_tag="LLC22_002024"
     CDS             complement(18143..19366)
                     /locus_tag="LLC22_002024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010706866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBK5435283.1"
                     /translation="MKIGFFTDTYFPQVSGVATSIKTLKQELERHGHEVYIFTTTDPN
                     ADKLEKDVIRMPSVPFISFKDRRVVVRGMWYAYLVAKELELDLIHTHTEFGAGILGKM
                     VAKKLKIPLIHTYHTMYEDYLHYIGKGKVIRQSHVKYLSRLFANHTTGVVCPSERVID
                     TLRSYGVIAPLRVIPTGIDIEKFKRSDITQQDISKLRESLGLQENHLMILSLSRISYE
                     KNIQALINGFPQVISAYPNARLVIVGKGPYVEELEELISELQLEEFVQFTGEVDNNDV
                     ALYYKAADYFVSASTSETQGLTYTEAMAAGTPCVVEGNAYLNRLFDHPSLGKTFETDE
                     DFAPALIDYISSEVPKDPKVLEAKLYDISSTHFGEAMIEFYQDMVVYHEEEMRRKEEE
                     DSIERIKIKLNSFKR"
     gene            complement(19383..20429)
                     /locus_tag="LLC22_002025"
     CDS             complement(19383..20429)
                     /locus_tag="LLC22_002025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 4 protein"
                     /protein_id="HBK5435284.1"
                     /translation="MKVLLYFESEKMLAKSGIGRALDHQKRALTEVGISYTLDEKEDY
                     DILHINTYGINSHNMVNKARREGKKVVYHAHSTEEDFRNSFIGSNQLSPIVKKYLVGL
                     YQKADYLITPTPYSKQLLESYGIRVPIQAISNGIDLEKYHPDPMKEQKFREYFKLSPD
                     QKVIICVGLFFERKGIIDFVEIAKKMPEYTFIWFGHVPMYSIPRNIRKIVKEDHPENV
                     LFPGYIRGEIIEGAYSGADLFFFPSYEETEGIVVLEALASKQNVLVRDIPVYNGWLED
                     SKNCYMGKTNEEFIRLIQQITNQELPSTTQAGYQTAKERSINKIGEELKNVYESVLNE
                     KVSSKLKKVNQVKD"
BASE COUNT         5557 a         4554 c         3486 g         6948 t
ORIGIN      
        1 ttatgctctc atcataccac aggttgaatt agaaaagaaa ataaatcaca caaaaaagca
       61 agacaatctg ttagtgagat tgtcttgctt ttcgaaaaag actgaatact tttcgttaaa
      121 actggttgct tagtcttcta atgccacatt atggaacaca tgctgtacat cttctagatc
      181 ttccagtgca tcaatcattt tttcaaatgt ttcttgatct tctggagata gtgttacctc
      241 gttttgaggg atcatttgga tctcagcgat tgaaaaatca gtgattcctt tttcttttaa
      301 tgcttcttgt atactatgga aatccgctac ttcaccgtaa acgatgattt gtccttcttc
      361 ttccattaca tcgcgaacat cgatgtcttt ttccattagg tattcaagga tctcgtcagc
      421 gtcttctcct gcaaaagcaa agattgctgt attgtcaaac atgtaagaaa ccgctccgga
      481 aacacccatg ttcccgccat ttttcccaaa tgctgcccgt acgtctgctg ctgttcgatt
      541 cacattgttc gtcaatgtat caacaatcac cattgagccg cttggtccaa atccttcata
      601 gcgcaattca gagtatgttt catctcctgc accttttgct ttttcgattg ctcggtcaat
      661 aatatgtttt ggtacattat aagttttagc gcgatcaatg acgaaacgta gtttttggtt
      721 tgcatgcgga tcaggatcac ctgattttgc tgccgcgtag atttcaatcc caaattttgc
      781 ataaatccgg ctattattag catctttagc agttttcttt gctacgatat ttgcccattt
      841 acgtcccata ttttcacttc gctttctgat ttgatagttt cataacgcaa aaacgtcctg
      901 ttccattata cttgtgaatc acgattctgt gaagcttttt ttctttcttc cttcattctt
      961 ctcattttta gtcaattatc tatactcgga ttgggatttg cccgaaattc tgttccggaa
     1021 tattgcctcc caattgatag atttgatcac ttctaactaa cagttccgct tcttgtgcct
     1081 ctttttttcc gattcgggaa taaatagaaa tctctttttt ttcttttaag aatcttcttc
     1141 cagcatcggt aaatccaagt agtcgaagat aatttttatt ttgttggaca ggaatctctt
     1201 gctttttgat attcagcaag acataacaag ataatcgttg gatccgtgtc catgtatatc
     1261 tttttgtttt tacctttgac acaaaatcct caaaactatc agcagttgca gctgctgttt
     1321 tcatgcgcga ttctattcct tcggtcatct gatagatatc tgtcagttcc agcaaagtag
     1381 aagataacaa ccgataacgc aaatacggcc aataagattc ccaagtctgc agcgaacaag
     1441 ttgaaagatc ttcttctgtc tgaggcggca caagtccagc tattcttttt ccttcttcta
     1501 acgcatggcg aatggctgtt gcactggcta tcctctgatc tgtgatgatt ttttcatgat
     1561 agcctgcact tttacgtcgg atcggatgta attccatagg gtggacatac ttggcatttt
     1621 cctttgcata acttaatccc aagatatgat ttggcgaaga aaaatcaagc gtaatatcgg
     1681 gatacagact gcgaaaaacc tcagtcattt tttgcggata actatacgtt tgatcagaca
     1741 gttcttgaaa tgcctcttct atcctatctt gattctcttg gacaaagcgt ccgaaactgc
     1801 tgtaatcaaa cgaagtctct tcttctgttc caaaacacaa actgtcacag tccagtgttt
     1861 gcaagatttt tactgcacct ttagcaaaat agtcagctga ctgaaccgcc cattcgacgg
     1921 gaagctccac tactaaatcc acaccatttt gtaaagcttc attcgcgcga tgccatttat
     1981 cgatgatagc cggttcgcct ctttgcaaaa aattcccgct cattacagca atgacgacct
     2041 ctgctcctgt tatttttcgt gccatttcca catgatagcg atgtccattg tgaaaaggat
     2101 tgtactctac gataatcccg cagcttttca tgcgcatcct ccttcatagt tatcgataaa
     2161 aaagaaatag agacaagtaa aaaaaggcaa aaatcggaaa aaatacccga actatataaa
     2221 ctattctcgc aaacacaata cttctgcgac gaaaagctgc actgcaagag caatgcctat
     2281 atcgttcgga tatataattt atgttgaaga tttattcttt tcttgttaac tcgagcaggc
     2341 aaaaccgcta gtctttgtat gctacaaaga accagcgctt tgatttctct gatgctgctt
     2401 cgtctgtaaa atcagaaaat gcttcgactt tcgaaaagcc gctgttttcc agcattctta
     2461 aataactttc caatggatag gtacgctctt gatgtagttc atcttcacga ataaatcgac
     2521 cagacccttc ttgttcttca acgaaaaagg taagaaaatg ttcgatgctg tgtttctcgc
     2581 ttcctggata actatcccac aaaaaagcaa aattatcccc ttgataatga tagctatatt
     2641 ctggaaaaac ctcatctact tgataggtgg agtgtacgtc aaataaaaat cggccatttt
     2701 cttctaacgc ttgatagact tcatcaaaca cttgctgtac ctcttgtcta tttttcatat
     2761 agcacagcga atcagaaaaa caggtaattg cctgatattg tccgatttct gataaatcga
     2821 gcatattgcc ttccacaaat tggatcgatg cgtcttcttc atatgctcgc tggctggcaa
     2881 tcatcaacat ctcttctgaa aggtctaacc ctgtcacttt atatccatct tttgcaaagg
     2941 caaccgctaa tgctccagta ccgcatgcca gttccaaaat attttttgtg tcttcttgta
     3001 aatgacgttt cgaaaaagct aaccattgct gataaagtgt ttcgtccatc acttcatcgt
     3061 aaatgaaagc aaatgtttca taagccatat gttaatccaa ccattcacta agatcgacta
     3121 gcggagcatc tgaccatagt ttttccagat tatagaaatt tcgttctggc gcatggaaaa
     3181 catgtacgat cacatctcca agatcgatca atacccattt tccgccttct tttccttcaa
     3241 tacgttttac ttcatatttg ttttcttctt ctttatcaat gatttcttct gtaattgcgt
     3301 tgatttgacg ttcgctattt gctgaacaga tcatgaaata atctgccaac aaggaaacat
     3361 ttcgaacgtc taaagcgata atgtcttctg cccgttttga atctgctgct tcaatcgcaa
     3421 tttttaattg ttctttacta tctatgatga tttcctccta atatgagcag cttatttttt
     3481 tgctacccag taattatatg tttcgattgt ttttggataa atctgttgtt cttgcgcaag
     3541 caaatgggcc aatgtatgtt ttgtttcaaa tgctacagct tcgtctagat cagcccatgc
     3601 aatggctcgt gcatcttgta ccccaggaaa atctcgacct ggttcaatat agtctgctac
     3661 ataaatgatt ttgtcaagga gactcatctt agcagcccca gtcgtatgca cccggattgc
     3721 atgaagaatc tctgcatcgg tgattcctaa ttcccgctct acaaacgaag cgccaacaag
     3781 accatgccag attgcattat tataattcaa taactccgga tcaaaaccgt ctcttacgat
     3841 taccattttg aactcctcat ctggtcgttc ttttgcataa tcatgtgtca atgcagcaat
     3901 actagctttt tcaggagaag caccgtattt tttggcaaga gccacggctg tttcttctac
     3961 tccaagcaca tgcttgaagc gttgttcgct cattctcatc tgtatttttt gcatcaggtt
     4021 ttctctagaa taagcagtat attcattact atagtccata ttcatacaac ccttcatttt
     4081 gaatataatc aattacttta tctggaacaa ggtagcggat agaacagcct tctttgatct
     4141 tttgacgtat tttcgtggaa ctgatgtcga tctcaggtac atctacccaa attacaggat
     4201 atggagtatc cgttgtgtat cctggtcgac gtatacccac aaagttgacc atagaagtca
     4261 gctcatcgat tttataccat tttggcaaat attctaccat atccccaccg ataataaagt
     4321 aataatctgt atccggattg ttttgcgtca attccttcat agtatcatag gtgtaacttt
     4381 tcccaccacg agctaattca atcgtttcaa tctgcaaaaa aggattgtct tccaccgcta
     4441 attccaacat gttgagtcga tgttttgcat caatcgtctg tttctcatca acatgaggtg
     4501 gctgataaga aggcatcaaa aatacgcggt caagacctaa attccggcca gcttgttcag
     4561 ccatcactaa atgtgcaagg tgaacgggat tgaatgttcc gcccaagatc cctacttgct
     4621 ttttcttctc taagaattga ggcatttctt caggaaataa ttgtgaacga acaaatgtct
     4681 tagcttgcgt attcatcatg gtcactcctt atattgcttt tacttctttt gatagccttt
     4741 gatacttttc ttttgtggaa ggtttgtata atacaataac acgtccaatg atttggacga
     4801 tttcgcaatc tatttctttt tctaatactt gagctgcttc ttctgcaatc tcatctgtat
     4861 tttgaagtaa cgatactttg atcagttctc ttttttctaa agcttcttca atttgaacga
     4921 tcattgctga attgatccca ccttttccga tttgaaaaat cggctgaaga tgatgcgctt
     4981 tgctacgtaa aaaacgcttt tgttttcctc ttaaactcat aattttcctt cttccttaaa
     5041 tcaatgcttt gcgtttcaat acatctacac cctttggcgc ccagcccgca attactactg
     5101 gcgctgttac agtgatccag cctagaccgg caaaaacgat gtctgttttt tctttcacag
     5161 aaaactcaaa acgaacaagc tccggaaatg cctcgacttc atcaggacga ggaggctgta
     5221 ataatccacc tacatgtttt tgataaaatt cgtctgcttt ttccagtttc gttcgatgaa
     5281 tatttacatc atttgacaca taagcaataa atgaagcacg attgccgctg ataaaatcaa
     5341 atcttgcaag tccgcccaag aaaagtgttt gcccttcatt cagctgataa actttaggtt
     5401 tgatttcttt taacggtgca atgatccgca aatctttttt acctaagtag tgcgccattt
     5461 gatggcgatg gataattccc ggtgtatcaa tcaaaaaatg cccgtcatct aaaggaatct
     5521 cgattttatc caaggtcgtt cctggaaact gcgaagttgt gattacatct tgtactcccg
     5581 ctgtattttt gatgatttga ttgataagcg tcgattttcc gacatttgtt actccgacga
     5641 tatagacatc ccgtccatcg cggtattctt cgattttttc taatagttcc gtcatctcat
     5701 gagatttctt agcactagtt aataatacat ctactggacg aattcctgct tcgtaagcac
     5761 gttccttcat ccattgtgtt aatttagttt ttttcaatga tttaggtaat atatccactt
     5821 tgttcccaac taaaagtact ggattgtcac cgacaaaacg gtgtagtcct gggattagtg
     5881 aaccattgaa gtcaaaaata tccaccacat tgacgatcaa tgcatctttt tgccctaatt
     5941 cattcagtaa gcgcaaaaag tcgtcatccg tcaatgagac atcttgggtc tcattataat
     6001 ggcgtaatct gaaacaacgc tgacaataga cttccccgga agctaaacct ttttccaaag
     6061 ccgtttgcgg cgtgtatcct aattcaccgg gtttgtttgt ttgtataacg gcaccacagc
     6121 cgatacattg taattcttct gtcattcgat tccacctcgc cagcccatat cagggtgttt
     6181 tgctaataga taggccataa ttcttttttc ccaaaaacga ttaaattgtg tcttccaact
     6241 atctgttgcg ataatgggtt ttacaaggat gctacgtatc cctgcacgat tggctccacg
     6301 tatatcagtc ataatctgat cgcctaccat tactatctca tcatctgcta aatccaattg
     6361 tttctttgct atgttgatcc ctcttgctaa aggtttcatt gctcgtgcaa catacaaaag
     6421 atcaaatttt tcaatcgctc gcgcgacacg ttttgaatta ttgtttgaaa caacaacaac
     6481 agggattcct gcatttttca tttctaaaat ccaagtaagc aactcttctg ttccatctgg
     6541 attattccat gcaatcaacg tattgtctaa atcggtcaat actgctttga tgcctagatt
     6601 ctttaattgg gcaggtgtaa tctgatagat ggcttctacc atccatgttg gtttgtaatt
     6661 tgaaaacatg ctgtctcctc atctgcaaaa aatgaaggag cacataaagt actcctcaac
     6721 cccgtattat actgcatatc agcaaaaaaa actacctcta tactcgttcg tctttcagaa
     6781 aaagcatttc tttacaaaat gaccaaaaat aaagattgat cacagaaaaa tttagaaaca
     6841 aaaaacaact aatattggcg gaacctcttg tatcgttttt ccagtaattt atgctgatct
     6901 aatcgaacaa gttccgtcaa tctttcaatc aacgcttttt tcataatgtg tgcgacttta
     6961 tatcgtggca actgctcgcc gttgaacgtt tcaggaataa ctcgatcaac gattcctaac
     7021 tcgcgtagtt ctggcgcagt aattttcatc aactcagctg cttctgcggc gcgactaccg
     7081 tctttccaca aaatcgacgc aaatccttct ggagaaagca cagcataaat cgtttcttcc
     7141 agcatccaga cttcatccgc taaacctaga gcaagggcac cgccacttcc accttcacca
     7201 atgatgatgg cgatgatcgg tacctttaaa tcagacattt cgagcagatt tctggcaata
     7261 gcctctcctt cgccgcgctc ttctgctcct acaccgcaat atgcacctgc tgtattgatc
     7321 aaggtaatca ccggtctatt gaacttttcc gcttgtttca tcagtcgtaa agcttttcga
     7381 tagccttcag gatggggaga accaaaattt ctgcggatat tttcctgcag atcccgtcct
     7441 ttttgaatac cgatcactgt taccggtttg ccatctaatc gagcgattcc accaacaatc
     7501 gcttcgtcat ctgcaaataa acgatcacca tggcattcct cgaaagaatc gaagatctct
     7561 tcaaaaaaat ccaagcttgt ccatcgttct ttagctcttg ctaactgaac gacatcatgt
     7621 gctgtcttat ccacgatcta tccatccttt ctgtgtatgc aattcaagaa gcgtatggat
     7681 tttctgtttc aattccatgc ggggaacaat ctgatcgaca aaaccatgag ataataagaa
     7741 ttcagccttt tggaaatctt ctggaagttc ctgcttgatc gtctgttcga tgacgcgtct
     7801 tccagcaaaa ccgatcaagc tttggggttc tgctagaata atatcgcctt ccattgcaaa
     7861 actggcagtt actcctccgg tcgtcgggtc cgttaaaaca gttagataaa aaagaccttc
     7921 attgctatgc cgtttgacag cagcagagat ttttgccatc tgcattagag aaaagattcc
     7981 ttcttgcatc cgtgcgccac ctgaagctgt gaacaagacg actggaagac tttcctttgt
     8041 tgctcgttcg aataatctgg tgatcttttc tccgacaatc gttcccatac ttcccatgat
     8101 aaaattagga tccatcactc caataatgaa gggaatcccc tgaatggttg ctttaccagt
     8161 gaggactgct tcatgaagtc ctgttttatc ttgcattttt ttaatttttt ccgtatattc
     8221 gggaaatgct agcggatctt tggttacaag atccgtatcc cattcttcaa aacttttttc
     8281 atcaataatc aaagctagac gctgccatgc accgattcga aaagcgtatc cgcaatgagg
     8341 gcatactttt tcttcaccga tgtctttcgt ataaaggata tgtttgcaat ttggacactt
     8401 tgcccacatg ttatcaggaa cagatggcga gttagcaggt ttgctctctc tattaggatt
     8461 gatccgaata tatttctttt tcttaaacag agccatctat gcgcctccta tctccgtttc
     8521 tggtgtccaa ttcggtaaaa attcttcttg taaaaatgct gtgctgtaat cacctgctat
     8581 gactgcagga tgactaatca aatccatctg aaattctgcg ttcgtgatga ttccttctgt
     8641 gataaattca cttaaggctc gctgcatctt cattaatgct tcaaaacgcg tatttccatg
     8701 gacgattatt tttgcaatca ttgaatcata atatggcggg atcgtatatc ccgggtaaac
     8761 tgcactgtct actcgcagtc ccatcccacc tgctggaagc agtaagtttt ggatcttccc
     8821 tggagaagga gcaaaatgga aagcaggatt ttctgcatta atccggcatt cgattgcgtg
     8881 tccttggaat actacttctt cttgacacac attcaaaggc tcaccggctg ctatctccac
     8941 ctgttttttt actaaatcga ttcctgtgac catttctgtt actggatgtt ccacttggat
     9001 tcgagtattc atttccatga aataaaaatc gccttcttca tccatcagaa actcgatcgt
     9061 tccggcattt tcataattga ctgctttagc tgctcgaaca gcagcgtctc ctagtgcttc
     9121 tctttttgtt tgtgagatca ctacagaagg agattcttcc agtacttttt gattgttgcg
     9181 ttgtaaagaa caatctcgct cgcctaaatg aatgacatga ccaaatcgat cacctaagat
     9241 ctgaacttct atatggcgag caggataaat gattttttcc aaatacatat catcatttcc
     9301 aaatgccgct gctgcttctt gctgagctga agaaaaatgc tgtgggagct cttcttttga
     9361 ttgaactttc cgaatgcctt tcccgccacc acctgcagct gctttcagca tcactggata
     9421 accaattctg tctgctattt ccaatgcttc ttctactgta gataatacac cagtacttcc
     9481 tggaatgact gggacatttg cttcttgcat caattgacgc gcattgatct tatttcccat
     9541 tgcatcgatc gttgcacttt taggaccaat aaatgtgata ttgcactctt cacacatgga
     9601 ggcaaatcgg ctattttcag ataaaaaacc aaatcctgga tgaattgctt cggcttttgt
     9661 cacgattgca gcgctcagta cttcctgaac attcagatat gaatcaacgg cttttgccgg
     9721 gccaatgcag attgcttcat ctgctaactg tgtatgaagt gcttcggcat ctgcttctga
     9781 atatatcgct acggtttgga tccctagttc gcggcatgca cgaatgatac gtacagcgat
     9841 ttcaccgcgg ttagctatca atactttaga aaacatattt cacctatcca atcataaagg
     9901 ttaattccgc ttcggctact tttttaccgt ctactttagc gattcctttg cctattccgg
     9961 ctgaagcttt cactttcaat atctcaactt caaggtataa ggtatctccc ggtgtaactt
    10021 tcttacggaa ttttgctttg tccaatccgc cgaaataagc cgtctttccc ttgaattgtt
    10081 caagagaaag taatgcaact gctcctgctt gagccattgc ttcaacaatc aatacccctg
    10141 gcataacagg ttcttctgga aaatgtcctt gaaaaaaggg ctcattgatc gttacatttt
    10201 tcttagcaac gatccgttct ccttcaacca tttcttccac tcgatcaatc aaaagcattg
    10261 gataacgatg tggaatgatt tcttttattt cttgtatgtt cattgttttc cctctttcct
    10321 gctttgctta tttttgctga atcctaaaga gtggctgtcc atattcgaca actgactcgt
    10381 tttctacaag gatttctgtg atcactccgt cggcctcact agttatctca ttcatcagtt
    10441 tcatcgcttc aataatgcag ataacttctc ctttggcaac ttgatcacct acttttttga
    10501 aagctggttt gtcgggcgct ggttgcagat aaacgattcc cacgattggc gaaacaacct
    10561 cgattccatc aaatactgcc gattcttttt ctttcattat ttctggagca gttgttgctt
    10621 gttcaggtat gacattgact ggctccgaaa ctggcaacgt ttcgtttgtt tgaaccatat
    10681 tcatgcctcg acttgtttta tttttattca tatacaattc aaattgacct tcacgcaaat
    10741 cgaattccgt tagcgaggat tgatcaaatt gactgactaa ttctctgatt tcattgatat
    10801 ccaaaattat tcctcccagc gtttcatgca cagaaccgca ttatgtccgc caaaccctaa
    10861 tgaattactc attgcataag taaaacttgc aggtttgctt tcgtttttga caactgtcaa
    10921 gtcaatctca ggatcttgtt tttctacatt gatcgtaggt gggataaatt gatgttctaa
    10981 tgccagcaaa gttgccaagg cttcgatccc gccggctgct cccaataaat gtccagtcat
    11041 cgatttcgtg ctgctgacgt aagtatctct gaaattttca cctaatgcga tttggattgc
    11101 ttttgcttct gcctggtcat tggctggtgt acttgttccg tgagcattga tatatccgac
    11161 ttgttccggc tgtacaccag cttcttccat cgcaagcttc attgctttag atgcaccaga
    11221 accatctgga gtaggagctg tcatatggta agcgtcacag tttgcaccgt atccaacgat
    11281 ttctccatag attttggcac cgcgagcttg tgcatgttct aaagattcaa gaactagaac
    11341 gcctgctcct tcacccatca caaaaccatt ccgattttcg tcaaacggaa tcgaaccacg
    11401 attaggatca gttgattctg agagtgctgt taaagctgca aatccagcaa tccccatctc
    11461 acaaatcgtt gcttctgttc ctccagcaag aatgacatca gaatagccat gtttgatgtt
    11521 acggaatgct tccccaattg aattcgttcc gctagcacaa gctgttacga tagctgtaca
    11581 aatacctttt gcacctacac gcaaagcaat atttccagct gccatgttgg caatcgccat
    11641 tggtacgaac attggagaaa ctcgttttgc acctttttca tgtagacgaa taacttggtt
    11701 ttcgattgtt ggaagaccac cgatcccaga tccgatgatg acgccaaacc ggtcttgatt
    11761 cattttttct ttatctaaac cgctcatctc cattgcttct aaagcagcgt agattccata
    11821 gatcgaaaac atatccattc gtttgctatc ttttttaata aaatatttat cgtaagggaa
    11881 atctttgact tcacccgcta aggtaatccc tgtttctgaa gcatcaaatt tagtgatcgg
    11941 tgcgatgcca ttcgtcccct cttttaagct attcaaaaag ctgtctgcgt catttccaat
    12001 aggtgaagtg actccatagc cagtaattac cactcgattc atttgtttgc tctccttttc
    12061 ttatccgtgc atgaccaatc cgccatcgac attgatgact tgtccggtga tatatggatt
    12121 ttgtgctaag aaaactgctg tttgtgcaat atcttctact tgtccgaaac gctgcatcgg
    12181 aatttgcttt tccgcttgtt ccttgacttt gtctgctaaa acttccgtca tatcagttgt
    12241 gatgaatcct ggcgcaatgg cattacatgt aatgcctcta gttgcagctt ctcgtgccac
    12301 agattttgtt aatcctacta cgccagcttt actagctgca taatttgctt gaccaatatt
    12361 tccaatcaac ccagatacac tagagagatt aatgatggcc ccttctcgct gcttcatcat
    12421 ttttttcaat acgtgctgcg tcatattgaa ggttccaatc aaattgatat ccagacattt
    12481 tttgaaatct tctgcatcca ttcgcatcac aagtttgtca tttgtgattc cggcattgtt
    12541 tactaacaca tggatcgatc caagcttttc ttctgcttct ttgatcattt gtcccgcttt
    12601 ctcataatca gagatgtcac cggaaactcc tacgcatttt acaccgaatg cttcgatttc
    12661 ttctatcttt tcttttggaa tctctccgcg accattcaaa atgatatttg ctccagcttt
    12721 tgcaaaagct aaggccatcg ctttgccgat tcctcttgta ctacctgtga taaatacatt
    12781 ttttcctttt acatccataa cgttcctcct tatagtattg ctattgtttc atcaaatgtc
    12841 tgcttattct caacacgcag aactggtatt gttttatcga tttttttcat aaatccgctt
    12901 aatacttttc cggggccgac ttcgatgact tgttcgatgc cgattgtttt taacttatgg
    12961 atactctcat agaaacgaac aggttgcatg acttgctgtt caagtagtcc cgcgattgtt
    13021 tctttcttca ttatttccgt tgttgtgttg cttatgatag gaaaagaagg ttcagagaat
    13081 tgaatctgac ttaggtcctt cgccagtttt tttgctgccg gttctaaaat agctgtatga
    13141 aaaggcccgc tgacatttag agggatcatt cttttgaacc ctttttcttt taatagtaaa
    13201 acagcttcgt ctactgcttt ttcttcgcca ccaatcacga tctgctgagg tgtattataa
    13261 tttgcaggag atacgatgcc gtacttgcta gcttcatgac agctttcctc gatcgtttca
    13321 atcggcgcat tcatcactgc aaccattttc ccgcttccag ctggggcagc ttctgtcata
    13381 taagcgcctc tttttgctac taacgcaact gcttcagtga aggatagcgc attactagct
    13441 actaatgccg aatattctcc taaactcagt cctaaagctg catctgggat gattccatgc
    13501 tccttcaata agcgataata cgcgatgctg actgttagaa tagctggctg tgtatattgc
    13561 gtctgatcca aacgttcatt ttctgtaaag caaagttcag ccatatcgta gccgagaatc
    13621 tcacttgctt catcaaatgt ctgctttaca acggcttctt catataaatc ttttcccata
    13681 ccttgatatt gtgcaccttg gccactaaat aagaatgctg ttttcatgtt tttctccaat
    13741 atatccagaa tatatgtttg attcttccta ttcaaaaagg ccgagacatt cctatttcag
    13801 gaaatgtccc agcccccaac ctaattttaa tgattatgca gtttgttttt ctacgtaagt
    13861 cactaaatct tgaaccgttt tgattccgtc ttctgtttcg attttcacgt caaattcatc
    13921 ttcaatttca ttgatgattt ggaataaatc caagctgtca gcttctaagt cttcttggat
    13981 gtcagtagtc aatttgattt cttcagtttc ttttcctaat tcttctgcga tgatttcttg
    14041 aattttttcg aataccataa taatatattc ctccgatatt gtttgctttt tatttttata
    14101 atttaacagt ctacaactcc atgagaatac ttccccatgt taaacctccg ccatagcctg
    14161 taaatattac tttctgctgt tttcctaagg tgatctttcc actagaaact gcttcatcca
    14221 ataagatagg gatgcttgca gcagatgtat tcccatattt atccatattg gtcaggaact
    14281 tttcttgcgg catctttact tttcgggcaa ttttctcaat aattctgagg tttgcctgat
    14341 gcaaaagcag ataatcaact ggtttgtctt tcatgacttc ttggatattg tttgcaacgt
    14401 ctcgtacggc aaaatcaaaa atatctctgc cagtcatttg caaataatac gaaccttctg
    14461 aatcttctga atagaacgga tttttatttt gctggtagcc agcggtcaat gagctacttc
    14521 tggtaccgtc agctgctaat ttttctttca gcaatttttt ctgtggattc gcttctaaga
    14581 gaatcccacc tgctccatcg ccaaacaaca cagcagtcgt acgatcagac caatcgatta
    14641 gcttagatag tgtttcacca ccaatcacca gtcccttagt tgagccgcag cggatcattt
    14701 tttcagccat gcttaacgca taaacaaatc ctgagcacgc agcactgata tcaaaagcga
    14761 tagcatgagt tgctcccaat ttcccttgta cttgtgctgc tacagatggt gtcgtgtaat
    14821 cgggcgacat tgttgctact aaaataaaat ccaaatcttt agggtttaga tttttctgtt
    14881 ttatcaattt ttccgccact aaaatgcata aatcagaagt ctcctgattt gttacacatc
    14941 ttcgttcacg aatacccgtc cttgacgaaa tccattcatc agaggtatcc atcatcttgg
    15001 aaagatcatt attagtaata atcttttcag gaaggacgct ggctgttgca gtaatcattc
    15061 caaattgttc cattaaatat cctcacttat agtcttgcaa gaagtcgtgc aagtttttca
    15121 gtgcatccag caaggcatgc tgttcctccg tagccattcc gtctaagatg ttcttgacca
    15181 tttcacgatg aaaatgctga tggacccgaa atagtaactt tccttttttc gttagtccca
    15241 actttacaac gcggcggtca tcttcactgc ggatacgttc gacatagcct ttttttacta
    15301 acttgttaat agcagtggtc aaggtcccaa cagtaattga tagttctttg gctacttctg
    15361 aagttgtttt tttcttgtac atcccgattg cctcgatcgt gtgcatctct gtgattgaca
    15421 gatctttgaa ttgagatttt ttcagctcag actcttcgat tgtcaaaata tcattgaaga
    15481 cactaacaag ataatcattt actgttttta aatctggttc catgttccac cgtccactaa
    15541 ttagtttgat tatcaaatct tttgatgttc aaactatatc ttaacttttt tcaaaatgca
    15601 accttaaaag atcatttttt tactatatga gcttttttta agattttact catttaaaac
    15661 aactgataaa tcagcattta taatttcttt tattagaaaa atcatctatc tcacatattt
    15721 tgattatcaa agtattttct gtgaacagaa ctatagaatt ccctaaaact tgtccattat
    15781 ttcaaaattt gttatagtct ttttattcaa agcgtaaaag gagatcctat gttaaaagaa
    15841 aaaatgaaaa ctctccccat gctgccgggt gtctatctta tgaaagaccg agatggtaag
    15901 gtcatctatg ttggtaaagc aaaacggctc aaaaatagag taagcagcta ttttcatcag
    15961 aataaacagc attcaaaaaa agtattacgt atgattcatc atataacaga ttttgatttc
    16021 gtcgtagtag acacggaatt agatgcttta ttgctcgagt gtcaattgat ccaacattac
    16081 cgtccttttt ataaccgaca aatgaattat ttcagtaatt ataattatgt acatattacc
    16141 aataagggat ttgtattaac agatactcct acggctcgaa catacgggcc ttttcgtctc
    16201 tataaaaaaa tgccgtctat tttgcgtata atggaagaaa cttatcaaat gccttggttg
    16261 tctgaaatta gtttgttagc tttgcgagtc cagcttcctg acctacagga aatgactttt
    16321 gaacagaaaa aaaaggaact ccaagggctg tttcaaggcc gaaataaaaa gctactgact
    16381 tacttgaaaa aaagacaaca acatttcatc tatcagttga atttcgaaaa agccggtatg
    16441 cttcaaaaag atatcgaatt agttacttat tttattagac ggatccagga acaaaagcag
    16501 tttttaagaa caccatcgct caccttcagc atgccattag cagcagatga gagtcagaaa
    16561 aagcactacc tcgtttgtta tggtcaactt gcagaaacaa tgattacctc tggtgacgtt
    16621 tctcctgact tctattatga aaagaaagaa gctcatttat ctttgaaacg tcaattgtca
    16681 aaagaagaaa tcgatcctgt acaaatcttg atcagttacc gcaaaaaatt agaaaaagaa
    16741 cagtttgaaa ttgaactgtt aaacaaaaaa gaagctgaaa agcaactaaa ttagttgctt
    16801 ctcggcttct tttaggcatc ttcaacttca aatgtcaatt atcctaaaat ttattggatt
    16861 aagtcataga tttccatcgc tacgatatcg atattatcaa attcgtattg ctgatgagta
    16921 tctgtttcag ttaattcaaa tgtatcggtc gctttatcat aagttactgt acacttctct
    16981 acgccttctt tttcaaaacg gcgaacttgc agttcattat ctgctgactc gaccatagcc
    17041 tccagtcgtt ttatgattgc gactaattgt gaatgtgtca tcggaggtcc tccttttctt
    17101 atttctgtta tattgtatca aaagcatagc ctacttgcat tgattttctc taaaaaaact
    17161 cgttttttat gatttttttt ctggtatttt tccttcaggc caccaaagtt tgatcaaagc
    17221 ttgggttccg tcattctcaa aacctttatc tgccaactct tcatatagtt tcaatgcttg
    17281 ggtagttgct ggcaatacaa gatccatttt ttctgcttct tctaatgcaa tctttaaatc
    17341 tttgataaaa tgtttgacaa aaaaaccagg tgtgtaatct tcttttaaaa tacgaggaga
    17401 ataattgctt aaagaccagt tagctgcact tccacctgaa agcgtctcaa tcactttctt
    17461 taaatcaagt ccgttttttt gtgcatagac aagcatttcc gtcattcctg tcatcgtacc
    17521 tgcaatcatg atctgattag ccatttttgt atgctgacct ttcccagcag aaccatgcaa
    17581 tgtaaatgtc gtaccaaatt ctttgaataa aggcagtact tgatcataaa cggcttcttc
    17641 tccaccgacc atgatcgtca gtgtaccatt ctttgctcct aagtcaccac cggataccgg
    17701 tgcatctaac gcatctgcgc ctttttcttt tgctgttttt gcaatttttt ctgccaggct
    17761 tggtgtactt gtagtcaaat caactaaaat atgtcctgag atatctgcag aaaaaatccc
    17821 cgactgtcca tagtagattt cttctacatc tttggggtaa cctaccattg taaagagaat
    17881 attactttgt tctgctaccg cttttggtgt atctgcccag atagctcctt ctgttactaa
    17941 aggatcagct tttgcttttg tccgattata gacagctact tcgtgtcctg cttctagtag
    18001 atggcgtgcg acagcacttc ccatgacgcc tgttccgata aaaccaagtt tcattttttc
    18061 gacctcctaa aaatcaaaaa tccttgcttc tatgctagta tacgctagaa acaaggattt
    18121 tttcataaaa aatgtttgaa ttttatcttt taaatgaatt taattttatt ttgattcgtt
    18181 caatcgagtc ttcttcttct tttcttcgca tctcttcttc atgataaaca accatgtctt
    18241 gataaaattc gatcatagct tcgccgaaat gtgtagatga aatatcataa agtttagctt
    18301 ctaaaacttt tggatcttta ggaacttcac tggaaatata atcaataagt gctggtgcaa
    18361 agtcttcgtc ggtttcaaaa gttttcccta atgaaggatg atcgaacaat cggttcaaat
    18421 aagcatttcc ttccacgaca caaggtgttc cggctgccat cgcttctgta taagtaagcc
    18481 cttgtgtttc tgaagtagaa gcactgacaa aataatctgc cgctttataa taaagtgcta
    18541 catcattgtt gtccacttct cctgtgaact gcacaaattc ttctaactgc agttctgaga
    18601 tcaattcctc taactcttct acataaggtc cttttcctac gataactaat ctggcgttag
    18661 gataagcgga gatgacctga ggaaacccat taatcaaggc ttggatattt ttctcataag
    18721 aaatcctgct taaagaaaga atcatcaaat ggttttcctg aagacctagt gactccctta
    18781 atttgctgat atcctgctga gtgatatcag aacgtttgaa tttttcaatg tcgataccag
    18841 taggaatcac gcgaagcggt gctattacac catagctgcg taatgtatca ataacacgtt
    18901 cacttggaca aactacacct gtcgtatgat ttgcaaataa tctagacaag tattttacat
    18961 gggattgcct gatcactttt cctttaccga tataatgaag gtagtcttca tacatcgtat
    19021 ggtaagtatg gatcagaggt attttcaact tcttagctac catcttccca agtatccctg
    19081 ctccgaattc tgtatgggta tgaataagat ctagttctag ttctttggca accaaataag
    19141 cataccacat gcctctaaca acaactcttc gatccttgaa agaaataaat ggtacacttg
    19201 gcattcgaat cacatctttt tccaacttat ccgcattagg atcggtcgtt gtaaaaatat
    19261 agacttcatg cccatgtctt tctaattctt gttttaatgt tttgatcgat gtagcaactc
    19321 cgctgacttg cggaaagtag gtatcggtaa aaaagccgat tttcatgttt ttcgcctcca
    19381 aactagtcct tgacctgatt tacttttttt aatttgctag agactttttc attcagtaca
    19441 ctttcgtata catttttaag ttcttcaccg attttattga tacttcgctc ttttgctgtt
    19501 tgataaccgg cttgtgtcgt actcggtagt tcttgattgg taatctgttg gatcagtcgg
    19561 ataaattctt cgtttgtctt ccccatatag cagttcttgc tatcttctaa ccagccatta
    19621 tacactggaa tatctcgaac aagtacgttt tgtttgcttg ctaaagcttc taaaacaacg
    19681 atcccttctg tctcttcata agaagggaaa aagaatagat ctgcacctga atacgcacct
    19741 tctatgatct ctccacgaat gtaaccagga aacaggacat tttcaggatg atcttctttt
    19801 acaattttcc ggatgttccg aggaatcgag tacatgggaa catgaccaaa ccaaataaat
    19861 gtgtattcgg gcatcttctt agcaatttct acgaaatcaa tgattccttt acgttcgaaa
    19921 aacaaaccga cacaaatgat tactttttga tccggagaca gtttgaaata ttctctgaac
    19981 ttttgttctt tcattggatc agggtgatat ttctctaagt cgatcccatt ggaaatagct
    20041 tgaatcggca cacggatacc atagctttcc aacaactgtt ttgaataagg tgttggcgtg
    20101 atcagatagt ccgctttttg gtacaatcct accagatatt tttttacgat aggagaaagc
    20161 tggttcgatc cgataaagga atttcggaaa tcttcctctg tagaatgcgc atgatagaca
    20221 actttttttc cttctcttct ggctttattg accatattat gactattgat tccgtatgta
    20281 ttgatgtgca ggatgtcata atcttctttt tcatctagtg tataagagat accgacttcc
    20341 gtcagagcac gtttttgatg atcaagcgca cgcccgattc cagattttgc aagcatcttt
    20401 tcactttcaa aatataataa taccttcacc ttacgtcccc cttcacttat atagtataac
    20461 atagcctaca aactgtcact caaacttaag ccctattttt gtctattctt actgacaaaa
    20521 acgttttctt aaaaaagaac aaaaa
//
LOCUS       DAFBVQ010000050        20182 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.052, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000050 DAFBVQ010000000
VERSION     DAFBVQ010000050.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20182)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20182)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20182
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.052"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            208..1014
                     /gene="proB"
                     /locus_tag="LLC22_002026"
     CDS             208..1014
                     /gene="proB"
                     /locus_tag="LLC22_002026"
                     /EC_number="2.7.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate 5-kinase"
                     /protein_id="HBK5435285.1"
                     /translation="MRKEIKNAKRIIVKVGTSTLIYPNGNINLAAIDQLAFVLSDLRN
                     RGKEVILVSSGAVGVGMHKLHLSERPTLIPEQQAAAAVGQAELMNIYNQRFSVYNQQT
                     AQILVTRDVVDYPESRKNVRNTLEQLLIMDTIPIVNENDTVAVDELDHLTKFGDNDQL
                     SAIMAKLVAADLLIVLSDIDGFYSDNPTTNPEAQMYRYIDKIDEKILAQAGGAGSTFG
                     TGGMQSKLKAASRIFEANSAMILANGKNPAIIFDILAGKEVGTLFKEDLK"
     gene            1011..2258
                     /locus_tag="LLC22_002027"
     CDS             1011..2258
                     /locus_tag="LLC22_002027"
                     /EC_number="1.2.1.41"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamate-5-semialdehyde dehydrogenase"
                     /protein_id="HBK5435286.1"
                     /translation="MTDLMQLGQQAKDSAQQLALMPTNRKNELLVQMAQTIKKNQQAI
                     IEANHKDLEKAVENNISETMQDRLQLTPERINAMATEIEKIASLDDPIGKVDEMWTNT
                     DGLRIGKKRVPLGVTGIIYESRPNVTTDAASLAFKSGNAVILRGGKEAFFSNQLLVQL
                     LQQVLVSAGESPYAIQFVDDTSHETAGQLMRLTEYLDVLIPRGGAKLIQRVKEQATVP
                     IIETGTGNNHVYIDKEAQLSMAVNIIVNAKASRPSVCNAAETLLIHSEIAPFFLPAIE
                     KELVEHGVSLRADARALEYLETAALAEDTDWDTEYLDYILAVKVVDSLDEAIAHINRH
                     NTKHSETIVTDSYAASQRFLNEVDAAAVYVNASTRFTDGSVFGFGAEIGISTQKLHAR
                     GPMGLNELTSTKYIIYGDGQIRE"
     gene            2334..2678
                     /locus_tag="LLC22_002028"
     CDS             2334..2678
                     /locus_tag="LLC22_002028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332250.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435287.1"
                     /translation="MFEILMIFFIYLISLNIAAFLGVGILSLFFQFKKRSIGSQREKW
                     SQYFDKIGQKGLVTRLHISYMVALCLLATINYYSFFDHSIAYTITLLIAGIFHLSYKY
                     QLNKNHLNRTFR"
     gene            complement(2795..3121)
                     /locus_tag="LLC22_002029"
     CDS             complement(2795..3121)
                     /locus_tag="LLC22_002029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266141.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435288.1"
                     /translation="MLEEYFQEVGLTLVELPIEFSDDRLIYRGYIKELPIINAEGETR
                     KAMQQKIAGMYQVYREQLLAESAEEEKEKTMNLSMDELLRYYDGETFDGFSLLNEEET
                     DLPGSW"
     gene            complement(3494..4696)
                     /locus_tag="LLC22_002030"
     CDS             complement(3494..4696)
                     /locus_tag="LLC22_002030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5435289.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
     gene            4813..5328
                     /locus_tag="LLC22_002031"
     CDS             4813..5328
                     /locus_tag="LLC22_002031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5435290.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            complement(5527..5973)
                     /locus_tag="LLC22_002032"
     CDS             complement(5527..5973)
                     /locus_tag="LLC22_002032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBK5435291.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(6020..7499)
                     /gene="msr(C)"
                     /locus_tag="LLC22_002033"
                     /pseudo
     CDS             complement(6020..7499)
                     /gene="msr(C)"
                     /locus_tag="LLC22_002033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
     gene            complement(7853..8482)
                     /locus_tag="LLC22_002034"
     CDS             complement(7853..8482)
                     /locus_tag="LLC22_002034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK5435292.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            complement(8466..8930)
                     /locus_tag="LLC22_002035"
     CDS             complement(8466..8930)
                     /locus_tag="LLC22_002035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5435293.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            complement(9417..10685)
                     /locus_tag="LLC22_002036"
     CDS             complement(9417..10685)
                     /locus_tag="LLC22_002036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBK5435294.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            complement(10916..11653)
                     /locus_tag="LLC22_002037"
     CDS             complement(10916..11653)
                     /locus_tag="LLC22_002037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5435295.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            complement(11720..12289)
                     /locus_tag="LLC22_002038"
     CDS             complement(11720..12289)
                     /locus_tag="LLC22_002038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBK5435296.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            12417..13289
                     /locus_tag="LLC22_002039"
     CDS             12417..13289
                     /locus_tag="LLC22_002039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5435297.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            13631..14503
                     /locus_tag="LLC22_002040"
     CDS             13631..14503
                     /locus_tag="LLC22_002040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5435298.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            14500..16458
                     /locus_tag="LLC22_002041"
     CDS             14500..16458
                     /locus_tag="LLC22_002041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5435299.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(16709..17560)
                     /locus_tag="LLC22_002042"
     CDS             complement(16709..17560)
                     /locus_tag="LLC22_002042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5435300.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            17683..18150
                     /locus_tag="LLC22_002043"
     CDS             17683..18150
                     /locus_tag="LLC22_002043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBK5435301.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            complement(18413..18895)
                     /locus_tag="LLC22_002044"
     CDS             complement(18413..18895)
                     /locus_tag="LLC22_002044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBK5435302.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(18995..19858)
                     /locus_tag="LLC22_002045"
     CDS             complement(18995..19858)
                     /locus_tag="LLC22_002045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK5435303.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
BASE COUNT         6067 a         4155 c         3663 g         6297 t
ORIGIN      
        1 tactcctatt ctaacatatc cgaggctgta aaagactttc tttacaaatt cttcaagaaa
       61 ttctgctatc ttaaagtaaa ccattaattc gttctttttc caaacgactg caagttgtac
      121 aaaaaaacta ttttttacat gactttactc gtcaaaacaa gtagaataga acgaaattaa
      181 tgagtggata tttgattgag gtgtcacatg cgtaaagaaa ttaaaaatgc aaaacgaatt
      241 attgtcaaag taggaacaag tacattgatt tatcccaatg gaaatatcaa tcttgcggca
      301 atcgatcagt tagcttttgt cctttctgat cttagaaatc ggggaaagga agtgatctta
      361 gtctcatcag gagctgtagg cgttggtatg cataaattac atttgtcaga acgtccgact
      421 ttgattcctg aacagcaagc tgcggcggct gttggtcaag ccgaactgat gaatatctat
      481 aatcaaagat tcagtgtata taatcaacag acggcacaga tcctcgtgac aagagacgtg
      541 gtagattatc ctgaaagtcg taaaaatgtg aggaatacat tggaacagct tttgattatg
      601 gacacgatcc ctatcgtgaa cgaaaacgat actgtagcag tggatgaatt agatcatctg
      661 acaaaatttg gcgataatga tcagctgtca gccatcatgg caaaacttgt cgcggcagac
      721 cttttgatcg tcctttctga tatcgacggg ttttattcag ataatccgac tacaaatccc
      781 gaggctcaga tgtatcgcta tatcgataaa atcgatgaaa agattctggc acaagcaggt
      841 ggtgctggta gcacatttgg aacaggcggt atgcagagta aattaaaagc cgcttctagg
      901 atatttgaag caaacagcgc aatgatttta gcaaatggaa aaaatccggc aattattttt
      961 gatattcttg caggaaaaga agtaggtact ttatttaagg aggacttgaa atgactgact
     1021 tgatgcaatt aggacaacag gcaaaagata gcgcgcaaca actagcactt atgcctacaa
     1081 accgcaaaaa tgagctactt gttcaaatgg cacaaaccat caaaaagaat caacaagcga
     1141 tcattgaagc aaatcataaa gacttagaaa aagcagtcga aaacaatatc agtgaaacga
     1201 tgcaagaccg cttgcagctg acacctgagc gaatcaatgc catggctaca gagatcgaaa
     1261 aaattgcttc gttagacgat cctattggaa aagtagatga gatgtggacg aacaccgacg
     1321 gattgagaat cggcaaaaag cgcgtgccac taggcgtgac cggcatcatt tacgaatctc
     1381 gtccaaatgt cacgacagat gcagctagtc tagcattcaa atcagggaat gccgttatcc
     1441 ttcgcggtgg caaagaagca ttcttctcga atcaattatt agtccaatta ttgcagcaag
     1501 tactggtcag tgctggcgaa tctccttatg ccatccagtt tgtcgatgat acttctcatg
     1561 aaactgcagg acagttgatg cgattgacag aatacttaga tgtgctgatt cctcgaggcg
     1621 gagcaaaatt aatccaacga gtcaaagaac aggcaacggt acctatcatt gaaacaggta
     1681 caggaaataa tcacgtatat atcgataaag aagcacagtt atctatggca gtgaacatca
     1741 tcgtcaatgc aaaagcttcc cgtccatctg tctgtaacgc ggcagaaaca ttgctgatcc
     1801 attctgagat cgcacctttt ttcttgccag ctattgaaaa agaactggta gaacacgggg
     1861 tctctttacg tgcggatgct cgtgcgttag aatatctaga gacggctgct ttagcagaag
     1921 acacagattg ggatactgaa tatctagatt atatccttgc tgtcaaagtg gtcgattctt
     1981 tggatgaagc aattgcacat atcaatcggc ataatactaa acattcagaa acgatcgtga
     2041 cagatagtta tgcggctagt caacgtttct taaatgaagt ggacgcggcg gctgtctatg
     2101 tcaatgcctc cactcgtttt acagacggat cggtatttgg ttttggtgca gagattggta
     2161 tctctactca aaagttgcat gcccgtggtc caatggggtt aaatgaatta acttccacaa
     2221 aatatatcat ttatggcgat ggacaaatcc gcgaataatg tttcgtgtga aacattattc
     2281 ccgccttttg ccttttttct gtaaaggttc tatccaacta gaaaggtgtc aatatgtttg
     2341 aaattttaat gatttttttt atttacctta tttctctgaa tatcgctgct tttctgggag
     2401 tcggtatttt atcccttttc tttcaattca aaaaacgaag catagggagt caacgggaaa
     2461 aatggtcgca gtattttgac aaaatcgggc aaaaagggct ggttacacgc ttgcacatta
     2521 gttacatggt tgcattatgc ttattagcga caatcaatta ctattctttt ttcgatcatt
     2581 caatcgctta tacgattacg ctactgattg ctgggatttt tcacttatct tataaatatc
     2641 agctgaataa aaaccacttg aatcggactt tccgctaaaa aatatccgta cgataagtag
     2701 agtgccttga agatcggcaa aaaactgccg gactttttag aggctgtgac aaagattttg
     2761 tcacagcctc tttttccata taaacggcgt tcgcctacca gctgcctggt aaatctgttt
     2821 cctcttcgtt aagaagcgaa aatccgtcaa atgtttcgcc atcataataa cgaagcagct
     2881 catccatgga caagttcatc gttttttctt tttcttcttc cgctgattca gccagtagct
     2941 gttcccgata cacctgatac ataccagcta ttttttgctg catcgctttt ctagtttcac
     3001 cttccgcatt gattattggc aattctttga tatagccacg ataaatcaac cgatcatctg
     3061 aaaattcaat gggtaattca acgagtgtca acccgacttc ctgaaaatat tcttccagca
     3121 tctattatcc ccccattctt tttcttaaat gaattttagc ttacctactg aaaattttcc
     3181 agtttcatta ttttgagaaa aaaagggaat gtgacaaaaa tcgtgtcaca tccccttttt
     3241 ccgaataaat ggtgttcttc tgccaactcc tcaatcataa gtcacaatat tcaacaaaca
     3301 tgagaaactg ttttttgaaa ttgttccttg tgattcagag ttaaacgaca gtctcacaac
     3361 ctcttggtaa acggcgttca aaagcttgca tctgcggtaa taagcccaac caaacgaaaa
     3421 atatgagaag ctatttttgt ttggctgttc ttatgacttg atgcaggaca gctttttcac
     3481 aacctctgat ttcttattct tcttcatttg tagcaaaata attacggtga taaatgatac
     3541 aacatacact gataagaaca atggcacctg caaaataaaa cgcatagctt tcaccaatat
     3601 gttcaccaat cacacctgca ataaatggtg ctaaagctcc accgaaaaag cggacaaaac
     3661 tatagctgga cgaagcaacg tttcgttgca gacctggtat ttccatagca atcgtcgtca
     3721 acagtgtatt gataattcct tggaaaaatc ctgctaacac aatgctgatc ggtacaagga
     3781 ctggcataga agttccagct cctaataaca gcaaacaaat aatgaataag acaaatgctg
     3841 ctaaaattgt ccgataagtc gtaaacttcc gctcaagagc cggtgcaacg aaaatcgaag
     3901 caatagccag aagcacaccc cagccaaaaa atacaaaacc gacttctaat tcagaatagc
     3961 caatcaataa aaatggcgca tacgcaagta aagtaaagaa tccgaaatta tataacaatg
     4021 cgattagtcc aactgaacga agtttatgat tgcttaacgc tttgacacct tcccaaaggc
     4081 ctacttttct ctttggtttc tcagtttcag gtaaaagtac cgctagggct ataaaaccgc
     4141 aaaacatcaa aaatgctacc ccaaaaaatg gataacgcca tgaaccactg cccaagaccc
     4201 caccgactag agggccaaca gccattccgc agccaagtgc tgcttcatac atcatgattg
     4261 ctttttctgt gttaccaact aaaatactga cgatcgttgc taaagcagta gagacaaata
     4321 aagcattccc gacaccccag ccggcacgta acccaatcag cattccgata ttcccagata
     4381 atccgccaag accagcgaat acaacgatga taaacaatcc tgtcatcaat gtttttttca
     4441 aaccgatccg actagataag aaacctgtaa atagcatcac cacaccagtg actaacatgt
     4501 aactagtaaa taacagggtc gtttcagctg gcgtagcgtt taactgtgca gcaatcgttt
     4561 ttaagattgg gtctactaga cccactccca taaaagcgat catacaggta gctgctacaa
     4621 ctagcgctga acttttcccc tttgtttctt catttgtttg ttcttgtata tctatttgat
     4681 tctccaatat ttccatccct ttctctctat tagcatcata catgatttat tttacatgta
     4741 aatatgcaca tgtaaaacgt ggaaacttta ctgtgatata ataaagaaaa taagacgaga
     4801 ggtaggattt ttatgaatac tttagcctat atattattat gcgtgctttt atccaaacca
     4861 cgttctgggt atgaattgaa gcagctgatc acaatttttt gggaagccca tcacagtcag
     4921 atctatacaa cgcttgccaa gttagaccag cagggttatg tgaccgtttt ggacaaagac
     4981 gagcactctc aaaaaaagat ctaccacttg actgatgaag gacgtgctct tgtagaggaa
     5041 tggatcaaag aggaaactcc cgctcctacg caaaaagatg aatttctagc aaaaatctat
     5101 gctttttcga cgctcgataa aacaacagct actggactgc tattcactag agaacaacag
     5161 ctgaacaaaa tcatgcaaaa aaatcaaaaa aaattgaatg acctctcgct agacaagaaa
     5221 caagaatttg gacgttatgt tgtgatccag cgcagaatta tgctttgtca gcaggaactc
     5281 caatggtgtc agcaagtaag agaacaaatg cagcagtttt ttgagtaagg gataaacaga
     5341 acctttctag aaatatctat tgaagagcaa attatcttca ataaaagagc aatacagttg
     5401 gaaaagaaaa agcgatccga acgacaggcc aaaacctatc gttcggatca ctatttttct
     5461 agaactgcat tcaagagact atgacaaaaa gcatgccaag gccttttttc aaataacagt
     5521 gttccatcat tcattacttt gaattgcttt tagcacactt cttgaaagcg ggccaacgat
     5581 gatcaactgc aacggtaaag cggcaatcac attcattttc caagcattca tataagcaga
     5641 gaataattga tcaggtattc cttgttccat gatcacaccg aataaagaca tacatgtcac
     5701 cattcctaaa accatcaagc atgaaatagt taagatcatt tggaccttgc tttctggatt
     5761 tactggtagt ttaaaggcaa tttttttcgc cagcacaccg atgatgaaga catccaaaat
     5821 gaaagccacc acgaatccag gcactagacc aatcaacaaa cttgataaat gaagatcttg
     5881 atgcagccat aaattatacg cgctcatccc caagaccatc aaaaaacaca tcattgttgt
     5941 aaaaattatt ccttcttttt tatttgtagg caatctgtac cactccttta aatttgtcac
     6001 gaaaatcatc gtagcacatt taaaaatttc tcgtaagtac tttttttatt ttctgccctt
     6061 ttatttcata aacttcatca gccgtacgct cgacaaagta agaatcatga gaagtaaaca
     6121 aaatcgttcc cggatatatt tgcattagct tctctaaagc ttcgatcgtt gccatatcaa
     6181 taaaattagt cggttcatct aacagcaaca cattacttgg cttagtaaaa agcaaagcaa
     6241 tcgtcagacg ggtcgcttct cccccactta atgtacataa cggtttcgtc aaagtttcct
     6301 gagcaaaccc taagtgattc agcaaactac ggacaagcga ttctgaaaac tctgtttgtc
     6361 tcatgacaaa acgaatgatg gattcttcag atgtcatttg ataacccttt tgctgatata
     6421 cttgaaagct tactttcgga gagagaagga ttccttctcc ttgtttgcgg atatgttcta
     6481 ataaggttgt cttacctgaa ccattttcac cgacaatcgc gattttttta cctaaagaaa
     6541 actgaaaatc accatttacc agtaatgttc tcccacttct ttccaattgg acattttgtc
     6601 ccatgatggg atagcggctg tggagttcaa gagattttgg tactggaaaa cggatttgtt
     6661 tcatctgctg cggcttggtt gtttctccta ttttttggag tcttctctct aatgttttcg
     6721 cattcttttg gatggctttt tgtacactgt ctttttgttt agaggaagac aaccgatccg
     6781 gtctgatttg ttgctttttc tttttactgg acactttttc caacttttcc gcttgttttt
     6841 tcttttcttg gatcgatttt tccaatcgtt ttttctcttt catgatcgac tctgcttctc
     6901 gtagctgagt ctttttctcc aattcctttt taagtgagat aggcactata attccccgaa
     6961 aactctcgga tttctccgtc ttttacttcc cagattttcg atgctagctc atctagaaaa
     7021 tagcgatcat gactaacaaa aaccagcgta ccataataat aacgaagctc ttcaatcagt
     7081 cgatcaatac tttttctatc tagatgggtt gttggctcgt ctagaagcat cccttgttca
     7141 taagaagaaa gaagacgtat caactcgatc tttcgttctt cccctccgct ccatttccgc
     7201 tctgaagttt cttccagtct taactggaaa tgactggcta attccaaatt taggtccttt
     7261 gcttcagcga gataggttaa ttgaggcagg tagttgaagg tgatctctgt ttggattttc
     7321 ccatgatcgg gaaaaagttc accggctatt agtttgagca aagtcgattt accgacacca
     7381 ttttctccta tgatccctat acgatcttgc tgatagacac gaagagaatc aatagatagt
     7441 tctagctggt tgccaaagct gacttgtaga tttgttatat ttactgctaa attttccata
     7501 tgttttacac tcctatttca tgtaaaacaa caattatcga tactaaaaaa gagcagaaaa
     7561 atctgtttgc aaaaaaactg catcacatct tttcctactc tgaacgaaat aactatgact
     7621 aaatcaccaa atctgtcata gctttcacct attctactgt cgttcgaaaa aatggacata
     7681 ctccatccat gaaattgttg tttatacatg tcttttgaat ttatttagtt gttattcaaa
     7741 agttcgaaac gtaatttcat cgatgcagtc atttttccga cctccttttt tattaggtta
     7801 ccacacacga ttcaaaaaaa gcaatagcta ctgaatagta actgaaaacc ttttattcga
     7861 acgtagtgat cttttctggt gctaaacgaa cagactcgta accttcttct accgcttttc
     7921 ctattgataa aataataact ggaacataac ggtctttatc caaaccaaat gcctctgcca
     7981 actgatctgc ttcgaatcca ccaattggat ttgtttcata gccatgatca cgcgcaacta
     8041 acatgaattg catagccgct aagctagaat cgactttgac tacatcgttc atttcttctc
     8101 ttgaaaaact cttgtaataa ggaatgatcg cagctaattg ttgatctctg acttcttttg
     8161 gcatcttccc tgattcgtaa gcttggttat agatttcttc gccatattcg taacattgca
     8221 tatcgccaaa aatcatgacc attgcagaag aagtatcatt ttgtctcgta ttgaaacgga
     8281 tcaaaggacg caagatttct tttgcttcct cgctttcagc gaccacaaag cgccatggtt
     8341 gcatattgac agaagaaggt gcagtcgtcg cttctttgat catttccagc atttcttcgt
     8401 gtgggatttt gtatgtttca tcatatacgc gaacggatct tctaccagtc ataattgttg
     8461 aaaaatcatt tttttgttcc attattatta acctctttcg tttctgttgt tatattgcaa
     8521 agttgggtat tcaatttatc taaaagtgtt agaaattgtt tcatttctac atcgctgaaa
     8581 gccggggata gcacggaacc tgtatcttta tggtccattt cacaatgctc gattttcttc
     8641 tgggcttttt ctgttagcgc tacatacact tcccggttgt tctgaggatt tctctgacgc
     8701 gaaacatagc catttgcttc caataccttc agatgacgag taactgctcc ttgatcaatc
     8761 tgcaactttt cttgcaaact gctttgtagc aatggatttt cttctttcag tctcatcatg
     8821 atctcgtatc tagtaagact tataccgata ttttcttcaa agatctggac gattttttga
     8881 tcggctaatt tgatttgata taaaaggtga ctaatctctt ctaaagacat aatttcctcc
     8941 tttctaataa ttgactcgtc aacgattgac ttgtcaataa tagaataaaa aaagaaaaaa
     9001 gtcaaagaat cagctgtgta ataaaaaaaa cgctctcaat agaaaagtat agagaaaaga
     9061 aattttttgt agaatgaacg gaaaaaatga taaagaaagc acaacgctaa aaccaagatt
     9121 attgattctt atcaaactat agaagatagc tcttctgcag tagaaaattt tacaccgcca
     9181 aaaatttccg aaatcgcctt ttgcaagaat cccgtcgaat attagaaatt ggatcagtat
     9241 gcttaaacag taataaaaaa gttatgacaa gatgttgtca caaccttttt tgagtaaacg
     9301 gtgttcaaaa acttgcatct gcggtaataa gttcaaccaa acaaaaaaca tgaaaatctg
     9361 tttttgtttg gctgttctta ctacttgatg cagggcagct ttttcactac ctctttttaa
     9421 taaccataaa atcctattcc ttcatatctc cagcccatcg gtgttagcca atctctttcc
     9481 ttagcactca aggtatagtg atgggtacca gttttttcat ttggattaaa tagtcgataa
     9541 attggcttgg aaccaccaga ataaaaactt agaccttcat aacgccaacc gatttttgtt
     9601 aaagagttga tctcagattg tgccattgtg taatgatggt ctccactgta aggattgtat
     9661 aaacggtaga caggttgtcc gctgtttggt gcttgccaag caatcccttc atattcccag
     9721 cctacagttg gcagataatt tttttctccg gcattcaatg tatataaatg ttctcctgta
     9781 tgacggttat acagacgata catcggagaa gttgaagttg gtgctgtatc atactgtgtc
     9841 agattatagg tttcgattac attgttcaat gtagaaccat aattaggcgc agtggcataa
     9901 cgacctgtta gccaagccgt agcatctttg taagagttcg tattgctttt ccatgcaccg
     9961 gaatagtagt aaacgcctgg ctgaaaagaa gtcgtcttca ataccgttac gttatcttgc
    10021 aatgattctt tgtacgaagg atattttcta aaagcggcat tcaccgtaat ccattgccca
    10081 ttcacatatt ccgaagtagg catcgtaaca gattggccat tatagcttcc tttaatccca
    10141 aatagattgt aattaggggc agaagccaaa gtactgttcc cccagccact ttcaacgatg
    10201 gcttgagcaa tcatgactga tgcatataag tcattggcac ttgccaaact ttgtgcagtt
    10261 gaggcaatac tatcaatgaa cgcttgttga gaattagcag atgagcgagc ataaaaagca
    10321 tagccagtat agttttcgaa ttcagacaaa tctgcttgat gggtatgtgt caatgtttgc
    10381 ccatctgtca attggttcgt gatttcttct gcattctctg gattgttctg agcttctgct
    10441 gatgtactgt cttcggtttg tgtttgttct gttgtttcag ttgttggttc ttcggttgaa
    10501 attgtatttt ctgagacagt agctgactgc aaagtactct ctgtatcgtt ttcaattcct
    10561 gtttctgaag aactcgatgt ctgagttgcg acagtttctg tcgattcttc agctagcact
    10621 gttgtgttgg caactgctag atttcctaaa agaataacgc taaataataa attctttgct
    10681 ttcatctttt ttctcctttg aattatgaaa cttttcctaa ataacagtgt aactaaaaaa
    10741 gtaaaagcaa gtcaatgtcc atatttaaat aacatttgtt tctttttgat gaatttgctt
    10801 tttctacata aaaagacgta aatgaagaat attcttctcc attcacgcct taaattgatg
    10861 gtcgtttgaa taactattta acaagtaatt ctctttggat attatccgtt atggattata
    10921 cttcctgtgt cgtcggacgg ataatcatgt tactgacaga catccggtct ggcgtttcta
    10981 tcgcaaatgc tacagcagaa gctatatctt cggaggtcaa tccccattct ttttgcgctt
    11041 catgaagttc aagagcagcc tttttgtcgc tgatggtttg atataattca gtttgaacag
    11101 ctcctggaga gatgatcgta gatttgatgt tattttgccg ttgctcttga cgtaatcctt
    11161 ccatgattgc acggacagca aattttgttc cgcaataaac ggcggaatca ggataaacaa
    11221 catgtcccgc cacagaatca gttgaaatga tatgcccaga tttttgtttt tccatgattg
    11281 gaagtacggc ggaaattcca tttaacacac ccatgatgtt gatatcaagc atattttgcc
    11341 attcatcacg gtgaccttca actaatggag cggttggcat gattcctgca ttattgtaca
    11401 atacatcgat tcgaccgaac ttttccatcg ctaaatcgat aactgcttgg acttgtgcaa
    11461 aatctcttac atctgctgtt tgaatatata gctcagcttc tggtaaagat tcttttattg
    11521 cttttaggcg atcttctcgg cgtgcagcta taactagttt agcccctttt tctgctaata
    11581 gcttcgttgt tgcttcaccg attccgcttg aagcgcccat gatgacaatc actttttctg
    11641 ataaatcatt cattctattc tcctcctgtt ttgaaaaatc tcttgcttat actcactatc
    11701 tcttatttca tcttactgtt caaataatcc gttcgacagg tttgacgatt ttggcaggga
    11761 ttcctgcaac gatggtattg tctgggacat ctttcgtaac agttgcattc gctgcaacaa
    11821 tggcattctc gccaatcgtt acgcctggca gaatagttgc tcctgctccg atccaagcat
    11881 ttttcttgat gtggattggc tttactgaca agcctcttcg ttcttttgga tcggttagat
    11941 ggttcaccgt gatgaggttg acacgaggac caatcaatac tgaatcttct aaacagatgc
    12001 cacctaagtc aacgaacatc acttgacgat tgataaagac atttttccct atactaatat
    12061 gtttgccgaa atctgtataa aaaggcagca gaacagtcac cgtatcatct actttgtcac
    12121 taatgatatt ttctagccgt ttgcggatat ctgctggttc atggtaccca gtattcagcg
    12181 ctgctaaagg ctcttcgttt tcagcttgga tctgatggat cacttcaaag agcggatccg
    12241 ttactcgaat ctctttattg acgatttgtt tttcgatgag gcttgtcatt ttgctccctc
    12301 cttttatcct tactttataa cggacggctt atcatgtcta atacttataa aacatactta
    12361 actattcctt ttaactatac ttagtggtat gcttttttaa aaacaggagg gaaaaaatgg
    12421 atattcgtat actgacgtat tttttagcag tagctagaga aaaaaatatc agccgagcag
    12481 caaaatctct gcatatcacg caacctactc tctcaaaaca actgaaagat ttagaagaag
    12541 aacttggtgt gacacttttc actcggggct cccgagagat acagttgacg gattctggtc
    12601 gatatcttta ttcaaaagga aaagaaatct tgtcgttggt agaaaaaacg gcgaacaatt
    12661 taacaaatga cgcaatcatc tctggagaaa tctacattgg cggaggcgaa actaaagcaa
    12721 tctctttcat ttctgatagc cttcattcgt tgatcaaggc gcatcctgat atccagtttc
    12781 atttatatag cgggaatgca gatgatatca tagacaaact ggatagcgga ttacttgatt
    12841 ttggactcgt aatcgaaccg acaaacaaac aaaaatacca gtcatttcga ctgccagccc
    12901 aagatcgttg gggacttttg atacatcgaa atcatccttt agcaaagcaa accgtcatcc
    12961 atccgcagga actgaaaact gttcctttga tcatttcccg gcaaacgtca gtggacagtc
    13021 aactagctga atggctaggt ttcagcatag atcagttatc gatcgtcgga acatataact
    13081 tattgtacaa tgcttctttg atggtcgata acgggacttt tggtgcatta gctctagatg
    13141 ggatcatcaa tacttatggg acggaaaaaa tattcatccc actcgatccg ccattacaag
    13201 cttcactgaa tctcatttgg aaaaaagacc agcctctttc tcctgctgct cgtaaatttt
    13261 tagatgtcct aacggagaaa tacagttaag tagagttttt ttccttcgct ttcagctttt
    13321 taacaacgaa taagataagc aaaagatcca acgattaaat aacataagtt tcttaattta
    13381 tttcttcctt ttatttctga taattccagt aaattactat aattataaaa aaagaattga
    13441 caaaacataa ctgtctatat aaaattgatt acgttaacaa taattcgttt catgtgacta
    13501 gatcatacta ggcatgaaaa atctctgagg aacatggttt ccctaggagg tttttcgtgt
    13561 ctatttttgt ttggccgcaa tcaactggtc tagcaaacgt gaaaaccaaa tcttcaaaaa
    13621 gggtgcgcgc atgaaaatca aaaagatctt taatcaaaat gcagtattgg tagatgacgg
    13681 tggacaggaa aaagtagcta ttggaaaagg gattggattt gacagaaaaa gaaatgattt
    13741 gatttttgat cgtgatgtcg aacggatatt tgtcatggaa ccagaaggtc aaatcaagtt
    13801 gcaaaattta cttaatcaga ttgatgaacg ctttttattt gcagcagaaa cgatcattga
    13861 tcatgcggaa actgttttga tggaaaagtt gaatgaacat gtattgatcg ctttgaccga
    13921 ccacattgct ttttctgcgg agaacattaa taacggtatc gtcatccgca acaaactttt
    13981 aagagaaatc gaagtgcttt acagtgatga attcagtatt gctcaatggg cagtagagta
    14041 tctgacaaaa gagcttggga ttccatatac ttatgacgaa gcaggatata tcgcaatcca
    14101 tattcacagc ggacgaagcg gtcggaacaa taaccatcgc agtatccgtg aagtgacgat
    14161 tgtatctgac atcatccatt tagtggaatc agaattggaa acagatatcc attcagaacc
    14221 attttcactg aattattcaa gactggtgaa tcatttacga ctacttctac aacgaaccca
    14281 tgcgcaacaa tatgctgttt tagacacgga aatcgtagaa atggtcaaac gaaaataccc
    14341 agaaagctat aagatttcta aaaaaatccg tgtgttgctg accaaagaat accagctcgc
    14401 gatcacgaaa gaagaactgg gttacttggc catccatatc gagcgtttaa gaagcgcaat
    14461 cgtacaaaca aatgttaaca atcatgagga ggaaaaaaat tgaaagcata tctacaacga
    14521 atgggacgtt cccttcaact tccagttgcg gtcttacctg ctgctgcttt actagtaggg
    14581 atcggaaact ggtgggcatc ttatagtaac gacattgtcg ctcatttttt acaagctggc
    14641 ggtaacgcag ttttaggtca attacctttg ctgtttgccg ttgggttagc actagggatg
    14701 tcagtggaca aatcaggtgc tgctgccttg gcaggtttgg tcgcatttga agttccagta
    14761 aatgttttaa aaactgattc agtagctact ttattgaata tcaaaccaga atcagttgat
    14821 ccatcttttg ctcagatcag taacgtattt attggtatta ttgccggatt gattgcggca
    14881 gctctttata atcgtttcca cgaagcaaaa ttaccgatgg ctttatcttt ctttagcggc
    14941 aagcgtctag tgccaatctt ggctgccttt gtcatgttgc tgatcagtgc agtgctactg
    15001 ctcgtatggc ctccggttta ctctgcttta gtttcttttg ctaaattcat tttgagttta
    15061 ggctggggtg gtgcaggtct ttatggcttc ttcaaccgtt tactgatccc tacaggattg
    15121 catcaagcaa tgaactccgt gttctggttt gacgtagcag gaatcaatga tattggtaaa
    15181 tttttggctt ctgaaggaac aaaaggcgta acaggaatgt atcaagctgg atttttccca
    15241 atcatgatgt tcgggcttcc agcaggagca tatgctattt acagaaatgc acgtccagaa
    15301 aacaaagcaa aaacagcttc cttgatgcta gcagcagctt ttgcttcatt ctttactggt
    15361 gtgacagaac cacttgaatt ttcatttatg ttcgttgctt ggccattata tgtcttgcat
    15421 gcaattttca ctgggatttc tttagcagtg agtgcattct tccattggac agcaggattt
    15481 gcctttagtg ccggatttgt cgattacttc ctatctttga aaaatccgat tgcgaatcag
    15541 ccattgatgt tgatcgtcca aggattagta acagcagtga tttactactt tggctttaac
    15601 tttgctatca aaaaattcca tctgatgact cctggccgcg aggaagcaga tctttcagat
    15661 gacgatactg caacgactaa ttcagacaat aaatatgcgg cacaagcaag caaaatctac
    15721 gctgcattag gcggagccga caatgtaact tcgatcgata actgtactac acgccttcgt
    15781 ttgcaagtca aagatacagg cctgatcgat caaaataaaa tcaaagccac tggcgtacct
    15841 ggtatgaaga tcatcgacgg aaaaaatgcg caagtcatcg taggtacaga agtacaattc
    15901 gttgcagatg agatggcaaa actacatggt ggtgctgcag cacgacctgc acaaacaaac
    15961 accgtggtta aaacagaaac atttgccggt gaaacgatcg aacaagatat ttacgctatc
    16021 gcaaatggga aactgattcc aatcactgaa gtttcagatg atgtattcgc ggaaaaaatg
    16081 atgggtgacg gctatgctgt attaccagaa aatggagaaa tcttctctcc aatcgctggt
    16141 acgatcacaa acattttccc aacgaaacat gctgtcggaa tccaaacaga tgctggtatc
    16201 gaagtcttgc ttcatatggg catcaacact gttgacttaa aaggcgaacc attcacttta
    16261 tatgtagaag aaggtcaaaa agtcgcaaga ggtcaattga ttgctttagt tgatcttgcc
    16321 gctattcaat ctgcaggcaa aaacacggat atggtcgttg tattcacaaa tggcgacaaa
    16381 gtccaaagct tagaaatcga acccgcacgt gatgtaaaag caaatgataa aatcggctct
    16441 gtttccaaca aagcctgagc catcgtcttc cccagacttt tttatcgata aacaaacagg
    16501 agctgagaca aaaatcttgt ctcagctcct ttttccgaat aaaaacggcg ttctcctgcc
    16561 aactccgcgg taataagtcc agctaaacga aacatatgaa gagctatttt ttatttgact
    16621 cttcttatta cttgatgcag aacagctttt tcacaaaatt tttcttcata ctcaaaacta
    16681 atcggctttt tcacaacctc tttatacatt attcctgatc caatatttct tttaatgctg
    16741 cttcaagaga agttaatggt tttcccaata ctttttctaa atcatcagag gaaatagcta
    16801 actgatcctt tttaatatca tgttggatcg ctaaaaacat gtcagctgct tcttgaggga
    16861 atccggcttc ttttagattt tcgacaaacg ctgcatcact tgcttcaata atttctaact
    16921 ctttacctgt cgcacgctct aatgccttgg ctaattcttc atagtcagtt agattgccgg
    16981 ataattctaa gatttctgga gagtcacttt ctactagtac ttttgctgca gcttctgcat
    17041 attcacgttt caatgcccaa cctgtttttc catttcctgc agcataaacg aattgaccag
    17101 tttttaaagc ctgcccaatg ataggtaatt cattctctac ataccaatta ttccgtaaaa
    17161 atgtatggga aatacctgaa tccttaatca ttttttcagt gaattggtga tctggcgcta
    17221 atacactgat cgagtgatcg gcatctgcaa aacttgtata agcgatataa gataccccag
    17281 ctgcttgtgc tgccttcact acattcttat gttcggcttg acgatttcct ggaacgccag
    17341 agacaaaaag caatcgatct attcctttca acgcttcttt cattgagtct aaatcatcat
    17401 aatcaccaat acgtatatta aatccagctt ctttcagtgc ttctcctttt tcttcactac
    17461 gtactagtac atagatttca ttttgtggaa ccatcttttt taagaattcc agcgcataac
    17521 caccaaaacc tccagttgct cctgttacta aataatgcat atttgccact ccctattctt
    17581 tttatttgtt aagatttaca gctgtacatt tataaattac acctttatca taaagagtgt
    17641 ggtaagataa gtcaagcaaa aaaaatgaaa ggatgacaac tgatgaagta ttctctgcaa
    17701 tttagtgatg caatccatgt acttgcctat attgaaatgt ttcaagatac ccgatcactt
    17761 tctagtgaga tgattgccag tagtatcgaa acaaatgcag caaatgtacg taaaatcatg
    17821 agtcagctca aaaaatccgg tttgatcttt acaaaaaccg gaaaaccgca gccttccctt
    17881 gccaaaagtc cagatcagat ttctttacta gatgtctatc gcagcatcga aggtaataca
    17941 cagcttatcc aagtcgatcc aaaaacaaat ccaaattgcg tcgttggtgc gaatatccaa
    18001 gaagctttag aagaaagcta cgctcggctg cagaaaaagg cagaagaaga aatggctaag
    18061 atcacacttg atagtctgat acataaaata gccgttttgg aaaaagaaaa aagaccagaa
    18121 aacacaggcc tcgtagagag atttttataa ttctctctac tgtgcctgca tttttctgat
    18181 cggaatcgtc tacataaatt cttttattct ccgggggaca aaagccttgt catgcccctt
    18241 tttcctctct aatgctcagg tcaaagcgct gaagtcatga cgtcttgata aacggtgttc
    18301 aagtagctga ccctcggcat tagttctgaa aaatgcaaaa tatggaaagc tatttcccat
    18361 ttttcctctc taatgctcag gtcaaagcgc tactttcacg acctctatat tatcatggtt
    18421 tattgactac cggtatccag atttctccca tatatttccc gttggtaact cccatttcga
    18481 ctacagcatt tggaccccca acataggcgt aatcttctac ttctcttaaa acatgcccaa
    18541 aggccgtatt cgtcaaatca tttcttaatt cttcaggcga ttctgctaaa gcgcttacaa
    18601 caagatacgt tccttttggg aatgggatga ttcgcgtagt gtttggaaca tcctgactcg
    18661 tttgaacacc gacatagtac atcattttcc cgttataggg ttcgttgact gtaaagaaat
    18721 aatgattttc agcagcttgt ttcaatgcat ctattgttcc attaccgata actttttgct
    18781 caaatgcttg tttctctgca gccaaaccga caaaatccgt attgctactc ttcaattcca
    18841 caccaatacc cgtcaccgta aaatctggtt tttcttcgat cctatacttt gccatttctc
    18901 ccaccctttc tattatatta agttcatctt acataaaatt aaagggaaat gacacgatta
    18961 cgctcttttt tctagggata tttttatttt ttaactattt ttttgctttc actgcaatcc
    19021 aaatctcact gtaaacatta ctgaaatcct ctccccattt tgtaaaagag atctcgggag
    19081 cttcgactaa cccataatct gaagaaggaa gccattctgc atagattttc ccccaagtat
    19141 cttgtaaagt ttggggaaat ggccctttat taggaaaaat ggcccaagtg tgttcttcta
    19201 tagcaagcat ttctaaatca gcgtacggat tttcttttgt cgtagcaaag ccaatcatgt
    19261 gcatcaaact gcccttttct tccaagcggt ctccatcaaa tccataagaa acgttgatta
    19321 cttgatttgg atataaatct cctaacttat gcatctcttc cctttgagtc tccgtgatcg
    19381 tctgcgctaa cttttgtatt tcttgattga ctccttcaaa tttgacagga acttttttcg
    19441 ccacacctgc cacataaaac tgttctttct tttcgatacg aaattccatc gattttcctc
    19501 ctctgacatc aataaaaaat gtcaagcgtg gaaaagattt ttgtatgccg tatctgctga
    19561 tttctgaagg cagatatcct gaccaatcac gaaaagctct tgaaaaacct tcgactgttt
    19621 catatccata tctaaacgcc gtttctgtca ctcttgatcc atctagaaga tcgcgattag
    19681 ccaaagccaa tctacggttt ttgatatagt ccattagcga catccctgca ataaacgtaa
    19741 agatgcgttt taattgatat tcagagattc ctgtattttc ggctattatt ttataggaaa
    19801 gtccttctgt caaatgttct tcgatgtaat cgatcaattg gttcagatct ttaagcatat
    19861 ttatcttcct ccttgattgc ctttttatca tattatcaaa gaaagtcaat tacttgatga
    19921 atcaggaacc aatttagtca gatgtagaaa atgttgtatg gatctaaaga aaattctcaa
    19981 gcagcgtttc gtaacggata attggtatta tctgcctatc tatgttttac ctttagaaaa
    20041 ataaattttg gggaagacag attctaagta aacaaagcgg taaaaatatc ttttattccc
    20101 ttagttaatc cgcttactac ctactgtaca aagcaaattg ttgttcaaac tgctgatcag
    20161 aacgctgctt ggatttttct tt
//
LOCUS       DAFBVQ010000051        18895 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.053, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000051 DAFBVQ010000000
VERSION     DAFBVQ010000051.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 18895)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 18895)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..18895
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.053"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(21..251)
                     /locus_tag="LLC22_002046"
     CDS             complement(21..251)
                     /locus_tag="LLC22_002046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435304.1"
                     /translation="MMEEFIRKNISDEYADFYDQSSKKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETNFKNRSE"
     gene            complement(687..1253)
                     /locus_tag="LLC22_002047"
     CDS             complement(687..1253)
                     /locus_tag="LLC22_002047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736967.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methyltransferase domain-containing protein"
                     /protein_id="HBK5435305.1"
                     /translation="MLQTALHFSHTLLQEILQPGDHVVDATMGNGHDTVFLAEHIGKT
                     GHVYSFDIQQQAIDATRERLEQRQLEERVSLFLQGHETLGEVIAEQQNLKAGIFNLGY
                     LPKSDKAIITMPETTRTAMEEILKRLVPRGRLILVVYYGHEGGEKELDMVDSFCSKLP
                     QETYNVLNYRFINQKNQPPILYCIEKKR"
     gene            complement(1253..2209)
                     /locus_tag="LLC22_002048"
     CDS             complement(1253..2209)
                     /locus_tag="LLC22_002048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390904.1"
                     /note="This family includes YhcC from E. coli K-12, an
                     uncharacterized radical SAM protein; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01212 family radical SAM protein"
                     /protein_id="HBK5435306.1"
                     /translation="MTFPYSEGNKRYHSWNYALRNEFGGKIFKVPIDGGFDCPNRDGT
                     VAHGGCTFCSVSGSGDMIVAPEDPLPIQFQKEIDMMHQKWPHVQQYIVYFQNFTNTHA
                     PVEIIKERFEQVVNLPGVVGLSVGTRPDCLPDEVVDYLAELNERMYLWVELGLQTTFE
                     ETSKLINRAHDYQTYLDGVAKLRKHNIRVCTHLINGLPGESLEMMKENVRRTILDSDI
                     QGIKLHLMHLMRKTRMLRDYHEGRLQLMSRPDYVNVICDQLEMIPKEIIIHRLTGDAP
                     WDSLIGPMWSLKKWEVLNAIDEELLRRDSFQGKYDVRKKVSV"
     gene            complement(2209..2865)
                     /locus_tag="LLC22_002049"
     CDS             complement(2209..2865)
                     /locus_tag="LLC22_002049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318868.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatase PAP2 family protein"
                     /protein_id="HBK5435307.1"
                     /translation="MKYKTSFQVAGSFFLVLFFILGWIVKFHLSWLSGFDQWFTGIVR
                     ASYPDLNSYQLFMTKFGNPLTVIILFACAALWMWYKKKRAETFWFVSGFIVIAGIINP
                     VIKLFFMRERPSLAHLVVETSYSFPSGHAAGSMILYGSLLFLLPAFVQKRTLRTLLQL
                     LMMFIIVSVGISRIYLGVHFPTDIIGGYLLSLSWLCLTYPVYREKRKQIDNSYRKKDF
                     "
     gene            3235..5253
                     /locus_tag="LLC22_002050"
     CDS             3235..5253
                     /locus_tag="LLC22_002050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736969.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5435308.1"
                     /translation="MENIARKERRRLEQTKRFRKAKRGAAIVGTAMVGCSVAAPLVQP
                     VPVQADETPVQFGARINTAAFITEIATYAQPIAQANDLYASVMIAQAVVESGWGSSAL
                     SQAPYYNLFGIKGSYQGQTVYMDTLEFLNNQWVNKKEPFRQYPSFAESFNDNAYVLRN
                     TSFGNGYYYAGTWKSNTKSYTDATACLTGRYATDPGYAGKLNNIIATYGLTQYDTPAS
                     GNAGGGATTGGNNTGSAGSTGGSSNSGNTNSGSATSTTYTVQSGDSVWGISNKFGITM
                     DQLIQWNNIQNNFIYPGQKLTIKGSQENGSSTNNSGNNTNSSGNAGTSNGGQTTGAKY
                     TVQSGDSVWKISNDHGITMAQLIEWNNIKNNFVYPGQQLIVSNGGSSNAGANTGSNTG
                     NTSGSSSSSSSSSNTASGTKYTVKAGDSVWSVSNKYGITMAQLIQWNNIQNNFIYPGQ
                     QLTVSNSGSTNSTSGNTGSSTNTNNSSSVNTGSSSSQGTYTVKAGESVWSVANKNGIT
                     MDQLIEWNNIKNNFIYPGQQLIVKGGTSANTNTGSTTSAAKPNTPNTSATTSTSSTGN
                     TMYTVKAGESVWSVANKHHITMDQLIEWNNIKNNFIYPGQQVIVKKGSSQSTNQQSVT
                     GSKTYTVKSGESVWSVADSHGITMAQLIEWNNIKNNFIYPGQTLIVAK"
     misc_binding    5323..5529
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            5680..8094
                     /locus_tag="LLC22_002051"
     CDS             5680..8094
                     /locus_tag="LLC22_002051"
                     /EC_number="6.1.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="leucine--tRNA ligase"
                     /protein_id="HBK5435309.1"
                     /translation="MSYNHKEIEKKWQKYWAKTNTFNTHDDPEKPKFYALDMFPYPSG
                     QGLHVGHPEGYTATDILSRVKRSQGYNVLHPMGWDAFGLPAEQYALDTGNDPAEFTQK
                     NIETFRRQINSLGFSYDWNREVNTTDPEYYKWTQWIFTKLYEKGLAYEAEVAVNWVPE
                     LGTVISNEEVIDGKSERGGYDVVRKPMRQWMLKITAYADRLLDDLELVDWPESIKEMQ
                     RNWIGRSVGANIEFKVAGTDKSYTVFTTRPDTLFGATYSVLAPELDLVREITTPEQKA
                     AVEAYIEETAKKSDLKRTDLAKEKTGVFTGAYAINPVNGKEIPIWIADYVLSSYGTGA
                     IMAVPAHDERDFEFAQTFGLEILPVIEGGDVEKAAYTEDGTHINSEFLDGMNKQEAID
                     KMNEWLEENGVGKKEVSYRLRDWLFSRQRYWGEPIPIIHWEDGTVTAVPEEELPLRLP
                     KTKNIKPSGTGESPLANIEEWVNVVDPVTGKKGRRETNTMPQWAGSSWYYLRYIDPHN
                     KKELADYEKLKRWLPVDIYIGGAEHAVLHLLYARFWHKFLYDIGVVPTKEPFQKLYNQ
                     GMILGENNEKMSKSRGNVVNPDDVVETYGADTLRMYEMFMGPLDASIAWSENGLEGSR
                     KFLDRVWRLIVDENNKMRDRITTLNDGKLDKVYHQTVKKVTEDYENLHFNTAISQLMV
                     FINEAYKVDALPYEYIEGFVQLLAPIAPHMGEELWAILGNDGGISYAPWPTYDEAALV
                     EDEVEVVFQVNGKVRAKSNVPRDLGKDELEKAALANEIVQEYIEGKTVRKVIAVPNKL
                     VNIVAN"
     gene            8442..9995
                     /locus_tag="LLC22_002052"
     CDS             8442..9995
                     /locus_tag="LLC22_002052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl hydrolase"
                     /protein_id="HBK5435310.1"
                     /translation="MDQELFIIEVLSAKQKIIEKAKKRAKRIMFKLLSLVFFSGLLFF
                     GAVSFLYRHMSAVVRSAEGMQKLNNLYHFSWGVGGITIVVLIVFLLLIWLRYHQLSRH
                     FDQWLSQRAQQFLHNKPTSQDDDYLYFEKTSTSQAFRIQKSDCQLLLRSLDDLPIYLG
                     ESKSKFGMNTFHIFLLENEPRWEKSQSSPGGYLTTKMSTLVTGFFLILLAGTIYYGRY
                     TQPKMSSHINAASHMTMNSTNDTHIQKTNEGLLADPKQKVNLTTQKINDLKLDTETHS
                     LYMTTDSGANWVFVPIDSQWLRFGEYTLTTGLIPEGYWMDNTYDISADFSWFIYSSGD
                     DVRLLTSRDNGKTWQTSIITQSVQPIRYRKAVFYGNDGLFICTSASGMSAETLYIYTT
                     MDGGITWIKSGSTMINQPVQNVSFVTTSLGFVSTRESLFYTNNGGRSFKESVLSIPEN
                     YQTGGIDLFQSPNEVTQISANTLETKFYLLKKGPIDAGKMFACLFRSTDNGETWQFVQ
                     QLSQVEQGD"
     gene            complement(10376..12160)
                     /locus_tag="LLC22_002053"
     CDS             complement(10376..12160)
                     /locus_tag="LLC22_002053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435311.1"
                     /translation="MEKKKTLNTRALIRFWKMIKPEHKYFYGLFLCSLFGNLLVVAMP
                     LIMGIGIDDLLSEIRKTGIGQLSFSDIKQALLFPVLLLIGCSVLSSITSFIQERTMAA
                     LSEKITLRVRKEITKKFKTLPMSFFDNHQVGDIISRTTTGLNQLSQVLLTGINQFFTS
                     VVTIAAAGLMLFYIESKLTLLVLLLIVGSSIVTTKIANKNKQISEQNQYELGVLNNRM
                     EEILAGNLVVKTFNQQAHAEAAIHEVNKKQYNAFKRAQFMNCAIYPAIRFINQLAFII
                     SAVFGAMLVLSGGVTIGFLQAYLQYINQISEPISTASYVINSIQSAMAAIDRIFEILD
                     ETDEIPDLPDARLLEQPKGKIAFKNVQFGYTSDKILMNQVDFSVKPKQTVAIVGPTGA
                     GKTTLVNLLMRFYELNKGKIEFDGLDITKLSRGELRRSFGMVLQNTWLFEGTVADNIA
                     YGKMDATREQIIEAAEIAQCDHFIRTLPDGYDTIISSENGTLSQGQQQLLTIARVILA
                     NPPVVILDEATSSVDTRTEALIQQAMEAVTKDRTSFVIAHRLSTIENADMILVMKNGD
                     IVEKGTHSELLQSPTLYASLYNSQFQIA"
     gene            complement(12175..13896)
                     /locus_tag="LLC22_002054"
     CDS             complement(12175..13896)
                     /locus_tag="LLC22_002054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313055.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435312.1"
                     /translation="MSILKTFLQKNKGLALLTFVMICLEIAGTLGVPKLVAKLIDTGI
                     ASGEASVIKKIGVEMLLVAFLGTIAAVASSYFSALASARFGFQTREKYFRKFQQLSMK
                     DISRFSSGSLLTRMTNDVDNVQQMIVLFCQMILPAPVICVFTILMMFRYSLLLTWVTL
                     ISVVFYVWIVYRLMKRGAPLSLSIQPKMDRITITLREFFTGINMIRAFDNQSYEEKRT
                     NKSFADYANQMIKVNRIFAWVTPIAFLLMGIVYASILWFGGNLVAEGALQIGVVTAVV
                     EYSMLTLAYLMIAAMVLVIIPKSFASLRRIEEILQAEIEIEEETIKTVAEPTFDQTNA
                     AAFEHVTFKYTEISDPVLEDIDFTIPKGKTTAIVGGTGSGKSSLAKLLLRLSDPTIGK
                     VTLGGIPLTQMTQEQIRSHISYVPQKAFLFSGTILSNLQMGNEYASTEELSKAIKIAQ
                     LEELVDTLPDGLDSFVAQGGSNYSGGQKQRICIARALIKPAEIYVFDDSFSALDYKTD
                     AALRAALHKHMSEKTLVIVAQRLSTIQQADNIIVLDEGKIVGQGTHEELLSNCQTYQE
                     FAKSQGI"
     gene            13996..14757
                     /locus_tag="LLC22_002055"
     CDS             13996..14757
                     /locus_tag="LLC22_002055"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5435313.1"
                     /translation="MKKMYTIGQVSELFDLPKSTIRYWDEQGLIRSSRQEENDYRLFD
                     IDDIFMLYDIVFYRKLDIPIKQMKNLYGKTLTELYETLDETERRIHKELVVMKQKQKE
                     IREQKKQLKLMIDTNEEEFPVEEIPFDCMISTEFEDIVEIKKFLPNYSSFGMMSMPAS
                     SSQTMYGFFIDPSEVHLFTQDVIWEKKDTAVYRRFLLKSEMNHAERNNILEIRERMYE
                     KGWKTGEVIGQYLLTNTDENNIRTEYYHAWIEMKK"
     gene            15724..15992
                     /locus_tag="LLC22_002056"
                     /pseudo
     CDS             15724..15992
                     /locus_tag="LLC22_002056"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013720767.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS607 family transposase"
     gene            16664..>18895
                     /locus_tag="LLC22_002057"
     CDS             16664..>18895
                     /locus_tag="LLC22_002057"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435314.1"
                     /translation="MRNKFHKLLSMFLVMLIVINQFGNITVLAESLAEQPERSLTIEV
                     DQEEAALGEQFQLRVRGTPDLLNALVIDKSEDLIEGEVKQLNDYERLITYSSQHSGKY
                     ELTARSGDIQSNTVSIEISVPEESTSESFNVPEESTSESFNIPEESLSESFNEARSSE
                     PSITQESQIERQEELLNYDIGISAERPTLPSRHTQTLKGYIQGGAGDILEEYGEMVVR
                     VPRASIGLIEFIRVEVADDSPLKPLAFYQEGTDVVFPFTFDYEGLNEAAQSYTFSITF
                     EVAFFQSGGTEPNNDFQVSLTYAERAANTEFSITPIPSSRPIFSKLYYGSREIDSQGN
                     LGNLLIDGQDVTNSNKFILQVNYEGSRKDGVVVTDVLPQGTTLAPNPTTWSSTGNREP
                     ISGGVRIAEVTNPGEANVRTHYVSEEFVDKVSFNKETNTLVVDFGNLAEGQSYFIEYA
                     LEVTDVDLFNEGRQEDGFSRNRASMTYNNQVMSRDYRLRIPESNLPAISLRKSVDKNV
                     INLNENELTYTLHVSMFSGTRNTLVIEDVLEEGMEFVSFLSDIPSFIDAEVNNGIVRF
                     SANNTIGGPTSFTLSFKVNVEAYAVGDQILNFATLVNSDNRLNTSTVRTRKIDGRIKV
                     IKTDENGQRLAGAKFEILSSDSQVIQEGITAENGEFLSEPLPVGSYQVRETEAPEGYL
                     LDATVHDVFINEYSIEEVTLTIENILDTGGVELIKHAEGSGEVLQGAVFELQNREGET
                     LQTG"
BASE COUNT         6205 a         3353 c         3786 g         5551 t
ORIGIN      
        1 ctcattaaaa agcataacca ttactccgat ctgtttttaa aattagtttc tacctctaat
       61 atatatcgag tttttatttt gccttcagag aatactgttt ctttttttgc agttacaggt
      121 tgtttatttt cggaaaaagc taatatagct aagattgaaa catccatctg gaatttatct
      181 tttttactgc tttgatcata aaagtctgca tattcatcac tgatattttt tctaataaat
      241 tcttccatca taaaaatcac ctcaaaacga ttatacgaac ttacgttctt gttgtaaagc
      301 gatatttgag gggcaaaaaa ggggcataat ttgactgata ttaagttagc tattgatata
      361 tgaatgacat acaaaaatat aaaatctttt aaaaatgctt atatatcaat gtttttgcca
      421 ttcttttata tatctgttat atgtcaaaaa aatgtgttca atttcaattt gtatttgaat
      481 aaagaggttg tgaaaaagct gtcctgcatc aagtaataag aacagccaat caaaaacagc
      541 ttctcatgtt tttgatttgg ttggacttat taccgcagat ataagctttt gagcaccgtg
      601 aataaagagg ttatgaaatc aacgctctaa cctgagtatt agagaaaaaa acgcaaaaca
      661 tatcatttat gttttgcgtt ttttatttat ctttttttct caatacaata taaaataggc
      721 ggctggttct tttggttgat aaaccgataa ttcagcacat tatatgtttc ctgtggcagt
      781 ttggaacaaa aagaatcaac catatccagt tctttttctc caccttcatg accatagtag
      841 acgacaagga tcaatcgtcc gcgaggcaca agtcgtttca atatttcttc catagctgtg
      901 cgtgtagtct ctggcatagt gatgattgct ttatcacttt ttgggagata ccctagattg
      961 aaaatccctg ctttgagatt ttgttgttca gctatcactt ctcctaacgt ttcgtggcct
     1021 tgtagaaaca atgagacacg ttcttctaac tgacgctgtt ctagcctttc acgagtagca
     1081 tcgattgctt gttgctggat atcaaaacta tagacatgac cagtttttcc gatgtgttct
     1141 gctagaaaaa ccgtatcgtg gccattgccc atcgttgcat ctacgacgtg atcccctggt
     1201 tgcaagattt cttgcagtaa tgtatggctg aaatgcaaag cagtttgcaa catcagacgc
     1261 tcaccttttt ccgtacatca tattttcctt ggaagctatc tctgcgaaga agttcttcat
     1321 caattgcatt caagacttcc cattttttca agctccacat tggtccaatc aaggaatccc
     1381 acggcgcatc ccctgtcaaa cgatggatga tgatctcttt tggtatcatt tccagctggt
     1441 cgcaaatgac attgacatag tcaggacggc tcattaattg aaggcgacct tcatgatagt
     1501 cccgcaacat tctcgttttg cgcatcagat gcatcaaatg gagcttgatt ccttggatat
     1561 ctgaatctaa aatggtgcgt ctgacatttt ctttcatcat ttctaaactt tcgcctggta
     1621 atccgttgat caaatgcgta caaacacgga tattatgttt gcgtaattta gccacgccat
     1681 ctaaataagt ttgataatca tgtgctcggt tgatcagttt tgaagtttct tcaaaagttg
     1741 tttgcaatcc aagttctacc cataaataca tccgctcgtt cagttcagca aggtaatcaa
     1801 ctacttcatc tggcagacaa tccggtcgtg taccgactga taatcctacg acacctggta
     1861 aattgactac ttgctcaaat cgttctttga ttatttcaac tggcgcatgg gtgtttgtaa
     1921 aattttggaa ataaacgatg tattgttgga catgaggcca tttttgatgc atcatgtcga
     1981 tttctttctg gaattggatt ggaagagggt cttcaggtgc aacgatcatg tctcccgaac
     2041 cagatacact gcaaaaagta caaccgccat gggcaacagt cccatctcga ttcggacagt
     2101 caaatcctcc atcgatcggc accttgaaaa ttttcccgcc aaactcattt cgtaaagcgt
     2161 aattccaaga atgatatctt ttatttcctt ctgaataagg aaaagtcatt aaaagtcctt
     2221 ctttctgtaa gagttatcta tttgttttct tttttctcta tacactggat aagtcaggca
     2281 cagccaagaa agactgagta agtagccgcc gatgatatca gtaggaaaat gaacgcccag
     2341 ataaatgcgg cttatcccga cacttactat aataaacatc atcagcaatt gaagcaatgt
     2401 gcgtaaggtt cttttttgaa caaaagctgg aagcagaaat agtaaagaac cgtaaagaat
     2461 catactgcct gctgcatgtc cactagggaa actgtaactt gtttcaacta ctaagtgcgc
     2521 caatgaagga cgctctcgca tgaaaaatag tttgatcacc gggttgatga ttccagcaat
     2581 tacaataaat ccagaaacga accaaaatgt ttctgccctt tttttcttat accacatcca
     2641 taaagccgca caagcaaata aaatgatgac ggtaagagga ttaccgaatt tagtcataaa
     2701 gagttggtag ctgttcagat caggataaga agctctgaca atgcctgtaa accactgatc
     2761 gaaaccagaa agccacgaca gatggaactt tacgatccag cccaaaatga aaaacaggac
     2821 aagaaagaag ctaccagcca cctgaaatga tgttttatat ttcatacaat tcctcctttg
     2881 aagcaatgac ttattatagc atttttggtc cagcgaaaaa aacggtaaag agataaaacc
     2941 aatgtatgat tcctctttga ataaccaata ttcttataaa aaaaataact gtaatcggaa
     3001 agacattttt tggtaatgca aatgaaatgt tagggaaata aaatcagtgt ttttcgaaat
     3061 ccttttaaac aagaacgtag acgtaggaag aacttgaaaa tgaacagaag ttgttcatta
     3121 cggtaaatta caatatgatt acaaaaaaca acaaagctct taaataactt ttaataaata
     3181 ttaagagaag ttataattat taataataga taaattgaag ttggaggata gaagatggaa
     3241 aacattgcaa gaaaagaacg gagacgttta gaacagacca aacgttttcg aaaagcaaaa
     3301 cgaggggcag caatcgtggg aactgcgatg gtaggctgtt ctgtcgctgc cccattagta
     3361 cagccggttc ctgttcaagc ggatgaaaca cctgttcagt tcggcgcaag aatcaataca
     3421 gcggcattta tcacagaaat tgctacttat gctcaaccaa tcgctcaagc caacgatcta
     3481 tatgcatcag tgatgatcgc acaagcagtt gtagaaagcg gttggggcag tagtgcgtta
     3541 tctcaagcac cttattataa tctttttggg ataaaaggca gctatcaagg acaaaccgtc
     3601 tacatggata cgcttgaatt tttaaataat caatgggtaa ataaaaagga gcctttccga
     3661 caatatcctt cttttgctga atctttcaat gacaatgcct atgtacttag aaatacttca
     3721 tttggcaacg gttattacta tgccggtact tggaagagca acacgaaatc ctatacagat
     3781 gcgacagctt gtttgacagg gcgttatgcg actgatcctg gttacgcagg caaattaaat
     3841 aatatcatcg caacttacgg attgacccaa tatgatacac cagctagcgg aaacgcaggc
     3901 ggtggagcga ctacaggtgg caataatact ggaagtgcag gtagtactgg cggttcaagc
     3961 aattctggta atacaaactc aggttcagca acttcgacca cttatactgt ccaatctggt
     4021 gattctgttt ggggaatctc aaataaattc ggtatcacaa tggatcaatt gatccaatgg
     4081 aacaacatcc aaaacaattt catttatcca ggacaaaaac tgacaatcaa aggtagccag
     4141 gaaaatggct cttcgacgaa taattccggt aacaatacca actcttcagg aaatgctggt
     4201 acatcaaacg gaggacaaac aactggtgcg aaatacactg ttcaatctgg tgattctgtt
     4261 tggaagatct caaatgatca cggaattacg atggctcaat tgattgaatg gaacaatatc
     4321 aagaacaatt tcgtttatcc aggacaacag ctaatcgtat caaatggcgg ttcttctaat
     4381 gctggagcaa atactggctc aaatactggg aatacaagtg gctctagttc gtccagctca
     4441 agttcttcta atacagcttc aggaacgaaa tatacagtta aagccggaga ctctgtttgg
     4501 agcgtctcaa ataaatacgg aattacgatg gctcagctaa tccaatggaa caatatccaa
     4561 aataacttta tctacccagg acaacaactg actgtttcaa acagtggatc aacaaacagc
     4621 acgtcaggta atacaggttc gtcaaccaat acaaataaca gcagttcagt taatactggc
     4681 agcagttcgt ctcaaggcac ttataccgtg aaagcaggtg aatctgtttg gagcgtggca
     4741 aataaaaacg gcatcacgat ggatcagtta atcgaatgga ataatatcaa aaacaacttc
     4801 atttatccag gacagcaatt gatcgttaaa ggtggaactt cggcaaatac aaatacaggt
     4861 tcaactactt ctgcagcgaa accaaataca ccgaatacgt ctgctacgac aagtacatca
     4921 tccactggta atacgatgta taccgtgaaa gcgggcgagt cagtttggag cgtagcgaac
     4981 aaacatcata tcacgatgga tcagttaatc gaatggaata atatcaaaaa taatttcatc
     5041 tatccaggac agcaagtgat tgtgaagaaa ggttcatctc aatcaacaaa ccaacaatca
     5101 gttactggtt cgaaaaccta tactgtgaaa tctggagaat ctgtttggag tgttgctgac
     5161 agtcatggaa ttacaatggc tcaactaatc gaatggaaca atattaagaa caactttatt
     5221 tatccaggtc aaacgttgat tgtagctaaa taaaatagct gttcgaagaa ataacgattg
     5281 aattccacaa aaatatttgt tactataagg ctacttaaat atgacaacac ttgaaaagga
     5341 agtagtaaaa agactgaagt ttcagagagc gcatggctgg tgagaatgtg cacggatgct
     5401 tttgaactcg cctttgagtt gcccttgctg aatacccgag taagcaagcg gcggtgacgg
     5461 ccgttacaac gttcgaggcc ttttcactaa ggtaaaatta ggtggtaccg cgtagattac
     5521 gtcctataaa aagagcaatc tttttatagg atttttttat ttcttttgtg aagtttgaga
     5581 aaacaaagca aaaggaaata aaaataaaca gattctgccg gttttttcgt tatatttata
     5641 atagaaacaa gtgttttcaa tagaacagga ggacagcaaa tgagttacaa tcataaagaa
     5701 attgagaaaa aatggcaaaa atactgggca aaaacgaata ctttcaacac ccatgatgat
     5761 cctgaaaagc caaaatttta cgcactggat atgtttccct atccatccgg tcaagggcta
     5821 catgtagggc atcctgaagg ttatacggca acggatatcc tttcacgtgt gaaaagaagt
     5881 caaggataca acgtgctgca tccaatgggg tgggatgcat tcggtctgcc tgctgaacaa
     5941 tatgcgctag atacaggaaa cgatccagct gagtttaccc aaaaaaatat cgaaacattc
     6001 cgacgccaaa tcaattcttt aggatttagt tatgactgga atcgcgaagt gaatacaact
     6061 gatccggagt attataaatg gacacaatgg atctttacga agctttatga aaaaggtcta
     6121 gcttatgaag cagaagtagc ggtaaactgg gtacctgaat taggaacagt tatttcaaat
     6181 gaagaagtga tcgatgggaa aagtgaacgt ggtggctatg atgtagtcag aaaaccaatg
     6241 cgccaatgga tgctgaaaat cactgcttat gctgatcgct tattggatga tctagaatta
     6301 gttgattggc cagaaagcat taaagaaatg caaagaaatt ggatcggtcg ttcagtagga
     6361 gcaaatattg aatttaaagt ggctggtacg gataaatcct ataccgtatt tacgacacga
     6421 ccagatactc tattcggtgc aacttactcg gttcttgcac ctgaactaga tcttgttaga
     6481 gaaattacga cccctgaaca aaaagctgct gtagaagctt atatcgaaga gacagctaaa
     6541 aaatcagatc taaagagaac ggatcttgca aaagaaaaaa caggagtatt tactggtgct
     6601 tatgcaatca atccagttaa tggcaaggaa atcccaatct ggatcgccga ttatgtatta
     6661 tcttcatacg gcacaggagc catcatggct gttccagcac atgatgaacg tgactttgaa
     6721 ttcgctcaaa ctttcggact agaaattctt ccagttatcg aaggtggaga tgttgaaaaa
     6781 gctgcttaca cagaagatgg tacgcacatc aactctgaat ttctagacgg catgaacaaa
     6841 caagaagcaa tcgataaaat gaatgaatgg ctagaagaaa atggcgtagg gaaaaaagaa
     6901 gtcagctatc gcttacgtga ctggctattc tcccgtcaac gttactgggg tgaaccaatc
     6961 ccaatcatcc attgggagga cggaacagtc acagctgtcc cagaagaaga gctaccatta
     7021 cggttgccta agacaaaaaa catcaagcca agcggtactg gagaatctcc attagcaaat
     7081 atcgaggagt gggtcaatgt cgttgatcct gtaacaggta aaaaaggccg tcgcgaaacg
     7141 aatacaatgc cacaatgggc aggaagctca tggtattacc tgcgttatat cgaccctcat
     7201 aacaaaaaag aactagcaga ttatgaaaag ttgaagcgtt ggctaccagt tgacatctac
     7261 attggtggag cagaacatgc ggtacttcat ttactatatg cacgattctg gcataaattc
     7321 ttatacgata tcggtgttgt tcctacaaaa gaaccattcc aaaaactata caatcaagga
     7381 atgatcttag gcgaaaacaa cgaaaaaatg tcaaaatctc gtggtaatgt agtcaatcct
     7441 gatgatgtgg tcgaaactta cggtgcagat acactgcgca tgtacgaaat gttcatgggg
     7501 ccattagatg cttcgattgc ttggagcgaa aatggcttag aaggaagccg taaattcttg
     7561 gatcgtgtat ggcgtttgat cgttgatgag aacaataaaa tgcgtgaccg tatcactaca
     7621 ttgaatgatg gcaagcttga taaagtgtat catcaaacag tgaaaaaagt gacagaagac
     7681 tatgaaaatc ttcatttcaa tacagcaatc tcccaattga tggtctttat caatgaagcc
     7741 tataaagtgg acgctctgcc ttatgaatat atcgaaggat ttgttcaact actcgcaccg
     7801 attgctcctc acatgggtga agaactatgg gcaatccttg gaaatgatgg tggtatttct
     7861 tacgcaccat ggccaacata cgatgaagca gcacttgttg aagacgaagt agaagttgtt
     7921 ttccaagtaa acggtaaagt tcgtgcgaaa agcaatgttc cccgagactt aggaaaagat
     7981 gagctagaaa aagcagcatt agccaatgaa atagtgcaag aatatattga aggcaaaaca
     8041 gtcagaaaag ttattgcggt accaaacaag ttagtcaata tcgttgctaa ttaattggct
     8101 ctttgtcaat aaggactgat gagttgtgca aaatcaaatc tgggccagaa tgaacttcat
     8161 tctgtctcag attttttgtt atttcaaatt gattaattga ttgatcaaaa aggttttgat
     8221 tttcatgttc tcaaacacgt tcaatgtctt tttcttctga atggtcttgt aagagatctc
     8281 tgtaatcatc aaatttttgt ctattaatct tagtattttt tgatgtataa actacctgaa
     8341 attgagagta cataccaaat tcataaattt tttattagtg ggactagtga ttgtatggat
     8401 tttgacgcat aatgaatgaa gtatgagaaa aggagagaca aatggatcaa gaactattta
     8461 ttatcgaagt attatcagct aaacaaaaaa ttatcgagaa agcgaaaaaa agagcgaaaa
     8521 gaataatgtt caagctttta agcttagtat ttttctctgg tttgcttttt ttcggagctg
     8581 tatcgttcct atatcgccat atgagtgcag tagtccgttc agctgaaggg atgcaaaaat
     8641 taaataattt gtatcacttt tcgtggggag ttggcggaat aacaattgtt gtgcttattg
     8701 tttttcttct acttatttgg ctccgttacc atcaattgtc gcgtcatttc gatcaatggc
     8761 ttagtcaaag agcacaacag tttttacata ataaaccaac ttctcaagat gatgactatc
     8821 tttattttga gaagacttcg acgagtcaag cttttcggat acaaaaaagt gattgccagt
     8881 tattgctgag atcacttgat gatttaccta tctacttagg cgaaagcaaa tcaaaattcg
     8941 gaatgaacac attccatatt tttttactag aaaacgaacc cagatgggaa aaaagccagt
     9001 cttcgcctgg tggatacctg acaactaaga tgagtacatt agtcactggt tttttcctca
     9061 ttcttttagc tggaacaatc tattatggga gatacactca gccaaaaatg tcttctcata
     9121 taaatgctgc ttctcacatg acaatgaact caactaacga tacgcatata caaaagacaa
     9181 atgaagggtt gttagctgat cctaagcaaa aggtaaattt gacaacacaa aagataaatg
     9241 atctcaaact tgatacagag acgcactctc tctatatgac aacagatagt ggtgctaatt
     9301 gggtatttgt gccgattgat tcgcaatggt tgcgttttgg cgaatacacc ctgacaacgg
     9361 ggctgattcc tgaaggttat tggatggaca acacatatga tatttccgcc gatttctcat
     9421 ggtttatcta ttcttctggg gatgatgtac gtctgctgac ttcaagagat aatggtaaaa
     9481 catggcaaac gtctattatc acccaatcag ttcagccgat acgttatcga aaagcggtat
     9541 tttatggcaa cgatggtcta tttatctgta catcagccag tgggatgtct gcagaaactt
     9601 tgtacattta cactactatg gatggcggaa tcacttggat aaaaagtgga agtacaatga
     9661 tcaatcagcc agtacaaaat gtcagcttcg ttacaacttc tttaggtttt gtttcgacac
     9721 gtgaaagttt gttttataca aacaacggag gacgctcatt caaagaatca gttctgtcga
     9781 ttccggaaaa ctatcagaca ggggggatag atctttttca atcaccaaat gaagttactc
     9841 aaataagcgc gaatacgtta gagacaaaat tttatttgtt gaaaaaagga ccaatcgatg
     9901 cagggaaaat gtttgcctgc ctcttccgtt caactgataa cggggaaaca tggcaattcg
     9961 ttcagcaact atcgcaagta gaacaaggag attaaagaag agagattgtg agcctgacgt
    10021 tcagcaccga gtcacaagaa acaaattcaa aaaacagctt ctcatatttg ttgaatagtg
    10081 taactcgtga ttcggagttg acaagagcaa caagaagcga ttttgaagta tagcttctcg
    10141 tattttacaa gatcgtgtct tattgccgat aggttgtctc ttgaacaccg tttattcgta
    10201 aaaagggatt gtgacaagtc ttttgtcact acttaccgaa cgaaactgaa ggagctatcc
    10261 aaaaagtatc attagtatta ttctttgtgt ttctagtggc accactagta catttaaaaa
    10321 agctatcgat catggactaa tcatacatga tcgatagctt tttagataat gtttgttacg
    10381 ctatctgaaa ttgactatta taaagactgg cataaagcgt tggtgattgg agtagttcag
    10441 aatgtgttcc tttttcgacg atatcgccat tcttcattac aaggatcatg tctgcatttt
    10501 caatcgttga caaacggtgt gcaatcacaa aacttgtcct atcttttgtc acagcttcca
    10561 ttgcttgctg aatcaatgct tctgttcgtg tatctacgct agaagttgct tcatctaaaa
    10621 taacgacagg aggattcgct agaatgactc gagcaattgt caataattgt tgctgtcctt
    10681 gagataacgt gccgttttcg ctagaaatga tcgtatcata tccgtctggc agtgttcgaa
    10741 taaagtgatc acattgtgcg atttcagccg cttcgataat ttgttctctt gtggcatcca
    10801 ttttcccgta ggcgatatta tcagctaccg ttccttcaaa cagccaggta ttttgtaaaa
    10861 ccatcccaaa agaacgacgt agttctccac gtgaaagctt ggtaatatca agaccgtcga
    10921 attcgatctt tcctttattc agttcataaa aacgcatcag cagattgact aaagtcgttt
    10981 ttcctgcacc agttggacca acgatcgcta ccgtttgttt tggctttact gaaaaatcga
    11041 cttgattcat caatatttta tctgatgtgt aaccaaactg tacatttttg aaagctattt
    11101 ttcctttcgg ttgttctaaa agtcttgcat ctggaaggtc tggaatttca tctgtttcat
    11161 ctaatatctc aaatatccta tcgattgctg ccattgcgga ttggatcgag ttgatcacat
    11221 aagaagcggt agaaattggt tcagaaatct gattgatgta ctgaagataa gcttgtaaga
    11281 agccgatcgt cacaccacct gatagaacaa gcatagcacc gaataccgca cttatgatga
    11341 aggcgagttg attaatgaaa cgaatggccg gatagatagc acagttcata aattgagcac
    11401 gtttaaaagc gttgtattgc tttttattta cttcgtgtat agcagcttct gcatgagctt
    11461 gctgattgaa tgttttgacc actagattac cagctaagat ttcttccatt cgattattta
    11521 aaacacccag ttcatactga ttctgttcag aaatctgttt gtttttgttc gcaatcttag
    11581 ttgtaacaat tgaactgcca acgatcagca ataagacgag caaagtaagc ttgctttcga
    11641 tataaaacag catcagacca gcagcagcta ttgttacgac agaagtaaaa aattgattga
    11701 tacctgtcaa taacacttga gaaagttgat tgagaccggt agttgtccga ctaatgatgt
    11761 cacctacttg atgattgtca aaaaacgaca tcggtaatgt tttgaatttt tttgtgattt
    11821 cttttcgcac cctcaatgtg atcttttcgc ttaacgctgc cattgtccgt tcctgaataa
    11881 atgaagtgat gctgcttaag actgaacagc cgatcagcaa taagacaggg aacaacaatg
    11941 cttgtttgat atcactgaaa gaaagctgtc caatacctgt ttttcttatt tctgataaga
    12001 gatcatcgat cccgattccc atgatcaagg gcatggctac gactaatagg ttcccgaata
    12061 aactgcatag aaacaatccg taaaaatatt tatgttcagg tttgatcatt ttccaaaaac
    12121 gtatcaaagc acgcgtgttc aacgtttttt tcttttccat cgtatccctt ctttctatat
    12181 tccttgtgat tttgcaaact cctgataagt ttggcaatta gacagtagtt cttcatgagt
    12241 accttgtcca acgatttttc cttcatctaa aacaatgatg ttatctgctt gttggattgt
    12301 actgaggcgt tgagcaacaa tcacgagagt tttctccgac atgtgtttat gaagggctgc
    12361 tcttaatgct gcatctgttt tatagtctaa agcggagaaa ctatcatcga atacatagat
    12421 ctctgctggt ttgatcaacg ctcgagcaat acatatccgc tgtttctggc cccctgaata
    12481 attagaaccg ccttgagcaa caaagctgtc caatccgtca ggaagggtgt ccactagttc
    12541 ttctaattga gcgatcttga tcgctttaga caactcttct gttgaggcat attcatttcc
    12601 catctgcaag ttgcttaaaa ttgtcccgct gaataagaaa gccttctgag ggacataact
    12661 gatgtgggag cggatctgtt cttgagtcat ttgagtaaga ggaataccac caagggttac
    12721 ttttcctatc gtagggtcac taagtctcaa gagaagtttc gccaaactac tttttccaga
    12781 tccggtcccg ccaacgatcg ctgttgtttt tcctttaggt attgtgaaat caatatcttc
    12841 tagaactgga tcagagattt cagtatattt aaatgtgaca tgttcaaaag cagctgcatt
    12901 tgtctgatca aaggttggtt cagctactgt tttgatcgtc tcttcctcaa tttcgatctc
    12961 tgcttgcagt atttcttcta tccgtcgtaa tgaggcaaac gatttaggga taatgaccaa
    13021 taccatagct gcgatcatca agtaagcaag tgtcagcata gagtattcga ctacagcagt
    13081 cacgacaccg atttgtaatg ctccttctgc tacaagattt ccgccaaacc acaaaataga
    13141 agcataaacg attcccatga gcaaaaaagc aattggagtg acccaagcaa atattcggtt
    13201 cactttgatc atttgattag catagtcagc aaagctctta ttcgttcgct tttcttcata
    13261 tgattgatta tcaaaggcac ggatcatatt aatcccagta aagaattctc tcaatgtgat
    13321 ggtgatccga tccatttttg gctggatact caaagataaa ggtgcccctc gtttcatcag
    13381 tcgataaaca atccatacat aaaaaacaac agagatcaat gtaacccatg ttagtaatag
    13441 agaataacga aacatcatga gaatggtgaa aacgcaaata accggtgctg gtaagatcat
    13501 ttggcaaaat aaaacaatca tttgctggac attatcgaca tcattcgtca ttcttgtcaa
    13561 aagagatcca gaactaaaac gactgatatc cttcattgac agctgttgga atttacggaa
    13621 atatttctcc cgcgtttgga atccaaacct agcggaagcc aatgctgaaa agtaactaga
    13681 ggcaactgca gcgattgttc ctagaaacgc tacaagcagc atttcaactc caattttttt
    13741 tataactgag gcttcgccac ttgctatacc tgtgtcgatc agctttgcta ctaattttgg
    13801 tacacctaat gtaccggcga tttctaaaca gatcatcaca aaggtaagga gagcgagtcc
    13861 tttgtttttc tgtaagaatg tttttaagat agacatatta ttcctccttt tttcctgata
    13921 cttttcgatt ctataccttc aagtaacttg aaggtcaata gaaaaaagaa taaactgaaa
    13981 aagaggtgag aaaaaatgaa aaaaatgtat acgattggcc aagtatcgga actatttgat
    14041 ttgccaaaat caacgatccg ctattgggat gaacaaggat taatccgttc aagtagacaa
    14101 gaagagaatg attatcgatt gtttgatatc gatgatattt ttatgcttta tgatatcgtt
    14161 ttttatagaa aattagatat accgatcaaa cagatgaaga atttatatgg aaaaacattg
    14221 acggagttat atgagacact tgatgaaaca gaaagaagaa tccataaaga actggtggtg
    14281 atgaaacaaa aacaaaaaga gataagggag caaaaaaaac agttgaaatt gatgatcgat
    14341 acaaacgagg aagaatttcc tgtagaagag atcccttttg actgtatgat ctcaacggag
    14401 tttgaagata ttgtggaaat caaaaaattt ctacctaact attcaagctt tgggatgatg
    14461 agtatgccag cttccagttc acagacgatg tatggatttt ttatcgaccc tagtgaagta
    14521 catttattta ctcaagacgt gatttgggag aaaaaagata cggctgttta tcgtcgattc
    14581 ttattgaaat ccgagatgaa ccatgcggaa cgtaataata ttttagaaat cagagaaaga
    14641 atgtatgaaa aaggatggaa aacaggagaa gtgatcggcc agtatctatt gacgaatacg
    14701 gatgaaaaca atatcagaac tgaatattat catgcatgga tagaaatgaa aaaataggaa
    14761 atatgtgttt aagataactc gaaaatgatg gttgttttag ttataaagaa aaattttctg
    14821 gttcgattac gggtttaatg tgggggatta ttagtcgtgg atagatagaa ttttagtttt
    14881 ttagaggaaa tatgtcttta aaaatggaat ggttgcaatt cttagcgata tatacgatgt
    14941 aattgtcctc ttaaaaaagt atggaaaaat aattgtattg ggtgttatgt ataattcatg
    15001 gtgaactgag actaatgaga agaaaaattc atattgttat gagtgagatt gtatcagatg
    15061 agaatgataa attaaatagg tgcataaaag cattacactt aaaatacatt gttgcttaca
    15121 ttattacaat atgttaataa ggcaaaaata aatagatgga ttgaataaac atatttttta
    15181 atcaaatagt ccctactgtg actttcctca gctatcggtg atactaccga tagcattttt
    15241 ttgcttataa aataattata agtatttaga gatttttctt ctaacattct tcaaacaaga
    15301 aaaatcacaa aggttattgt tatttttata tattcttttt aagaatgatt gtttttttat
    15361 agaaatttta aaaaataaaa cacgttattg atggatagtt agtttgttat ttggtaatat
    15421 tatagaagtt gactggtagt gatttatttt tcgtcgtttt ataaaaatgt tattttttgg
    15481 aaaaattcac aaatatgtaa cgaatgtttt tctggaattt gctgtgttaa aaagcagtat
    15541 gactaatata aatactattg tcatttatgc aattttttat ggatagtaat tttagagggg
    15601 aatcaatgaa ggaagaatag aagggaaaaa tagttgcaaa tacgccagtt agcaaaaata
    15661 gcaatacatc ttcaagcttt aaaattcgag agaatcatct tggtagtgga atcaactaca
    15721 acaaaaggat taaaccaatt aatagataga attaccaatg gaaaaataga aaaggtagtt
    15781 attctataca aaagttgttt aattcgcttc ggttatgaac ttagtgaaac cctttgcaat
    15841 atatggtaca gaatatagaa attattgaca ttacagaaaa tgatgaagat ttaatacaga
    15901 ttgtcactat ttgtagatac cttttacaag gaaaccgagc caataaagct aagaagatga
    15961 ttaaggagtt gatggaagac gatacaagtt aagaaagtga aactacgccc aaataaagag
    16021 caaaaagagt aattggacgt ggaaaatgca agaaatgaac catcgattcg gtggacagtt
    16081 tattagtaat gacggtttga gaacatccat gacgagaatg aaggaacatc ctaaatgcgt
    16141 ttagttgaac caagtgccaa ataatatggc caaataagcg atcagttatc gatgaatccc
    16201 aagtattcta aactatatat tcattttgat gctaagcatt gatatatttt tttgggattg
    16261 atgaaggtta accaatacag ggactcactg atgaaattct agagtctgac cttggtatca
    16321 acgatttagt gattgtttct aatggaaaag tataaaagta tataagtaca ttaacaaaat
    16381 aactattagg gttacgctcc agcttgtgca aggcactggc aggaggaatc gtgaaatcat
    16441 aattatggtt aagccacacg gacaactaaa agtcatacaa agctatcgaa tcaatcaaca
    16501 gaagacaatc ggcaatcatt agctttgttt acagcttaca ttgcaacgct tgagttgaac
    16561 cgaaaatacg agggaggtaa cgcagccatt ttgagttggg gaatcttttt agaaaattat
    16621 cgggtacctt gttgtttagt caaaattata agggggagta atagtgagga acaaatttca
    16681 taaactgtta agtatgtttc tagttatgct tattgtgatc aatcaatttg ggaacataac
    16741 ggttctagct gagtctttag cagaacagcc agagcgttcg ctgacgatcg aagttgatca
    16801 agaggaggct gctttgggtg agcagttcca gttgcgagtc agaggaacac cagacctgct
    16861 aaatgcattg gtcattgata agagtgagga tttgattgaa ggggaagtga agcaactcaa
    16921 tgattacgaa cgtctgatta cttattcttc ccagcattca ggtaaatacg aattgaccgc
    16981 aagaagcggt gatattcaat caaatacggt ctcaatagaa atcagtgtac cagaagaaag
    17041 cacaagtgag tcttttaatg taccagaaga aagcacaagt gaatctttta atataccaga
    17101 agaaagctta agtgaatctt ttaatgaagc cagatcatct gagccatcta taacgcagga
    17161 atctcagatt gaaagacaag aggagctctt gaattatgac atcggcatct ctgctgagcg
    17221 ccccactttg ccgagcaggc atacacaaac gttaaaggga tacattcaag gaggcgctgg
    17281 cgatattctt gaagaatatg gggagatggt cgtacgagtt cctagagcat cgattggctt
    17341 aattgagttc attagagtgg aggtcgctga tgattcacct ttaaagccac tggcatttta
    17401 ccaagaaggc acagacgttg tttttccatt tacctttgat tatgaaggat taaatgaagc
    17461 cgctcagtcg tatacattca gtatcacgtt tgaagttgct ttctttcaat caggcggtac
    17521 tgagccaaat aatgactttc aagtgagtct tacttatgct gagcgagcag caaacacgga
    17581 attttcaatt acgcctattc cttcatcaag acccattttt tcgaaattat actatggctc
    17641 tagagaaatc gacagccaag gaaatcttgg gaatctgctg attgacgggc aagacgtgac
    17701 caacagtaat aaatttattt tgcaggtaaa ttatgaagga tcacgaaaag acggtgtagt
    17761 ggttaccgat gtactaccgc aaggaacaac tttggcaccg aatccgacta catggagttc
    17821 cactggaaat agagaaccta tttcaggtgg ggttcggatc gcagaagtaa cgaatccagg
    17881 tgaagcaaac gttagaactc attatgtttc cgaggaattt gtggacaaag tatcttttaa
    17941 taaggaaacg aatacacttg ttgtggactt tggtaatcta gcagagggtc aatcgtattt
    18001 tattgaatat gctcttgaag tgaccgatgt cgacttgttc aatgaaggaa gacaagagga
    18061 tgggttttct cggaatcgag cgagtatgac ctacaataat caggtaatga gccgagacta
    18121 ccgcttgaga atccctgaaa gtaatcttcc ggcaatctct ttaagaaaaa gtgtggacaa
    18181 aaatgttatc aatctcaatg aaaatgaact aacgtatact ctgcatgtct cgatgttttc
    18241 tggaacaaga aatacgcttg ttattgaaga tgttttggaa gaaggcatgg aatttgtgtc
    18301 atttctatca gatattccct ctttcattga tgccgaagtc aataatggaa tagttcgttt
    18361 cagtgcgaat aatacgattg gtggtccgac aagttttacc ctctctttta aggtcaatgt
    18421 agaggcgtat gcggtcggcg atcaaatttt aaactttgca acgcttgtga atagtgacaa
    18481 tcgattgaat acgagtactg taagaacaag gaaaatcgat gggcgtatta aagtaattaa
    18541 aactgatgag aatggccaaa ggctggcagg agcaaaattt gaaattttat caagcgattc
    18601 acaagtgata caagaaggta taacggcaga aaacggagaa tttttaagtg aaccgcttcc
    18661 tgtaggtagc tatcaagtcc gagaaacaga agcaccggaa gggtatcttt tagatgcgac
    18721 ggtacatgat gtttttataa atgaatactc catagaagaa gtgacgttaa ccattgaaaa
    18781 catccttgat acgggtggtg ttgaactaat taaacatgct gaaggcagtg gtgaagtcct
    18841 tcaaggagct gtttttgagt tacagaaccg agaaggagaa acgctacaaa ccggt
//
LOCUS       DAFBVQ010000052        17742 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.054, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000052 DAFBVQ010000000
VERSION     DAFBVQ010000052.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17742)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17742)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17742
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.054"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(32..1333)
                     /locus_tag="LLC22_002058"
     CDS             complement(32..1333)
                     /locus_tag="LLC22_002058"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBK5435315.1"
                     /translation="MVINFIILFLMIAITSFFVASEFALVKIRRSRLEQLEKENVKNA
                     KLALHVTHHLDNYLSASQLGITLTGLIIGWVGEGSVAALLEPVIGKLPFSSAISSTIS
                     VALGFILVTYIDVVIGELLPKSYSIVNTEKVVLFVVKPLHYFYKVMFPFIWVLNHSAA
                     GLGKLLGVRLVSEGEETLSQEELTLVALNSYEKGELTKEEYHYLENVFEFDDTLAKDI
                     QVDRTSMQVFEASETVKEAIKASIEQGHTRYPVILESKDNVLGYVTLPDLIKQSYKDD
                     QLTVEQLIEEPIVTTETIPIKKLLTIMRKKGKHIAILKDEYGGTSGLVTIEDILEEIV
                     GEIRDETDLDEALIAEQSDGSYIISGKLTLDDFQRYFHVEIPEFEETNFTTLAGFASS
                     RYKEIKAGTIIEIASFRFTVLEYQHAHIDYFKVESTERKIE"
     gene            complement(1563..3521)
                     /locus_tag="LLC22_002059"
     CDS             complement(1563..3521)
                     /locus_tag="LLC22_002059"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="KUP/HAK/KT family potassium transporter"
                     /protein_id="HBK5435316.1"
                     /translation="MAGLLVAMGVVYGDIGTSPLYVMKSIVEDNGGLSGINPDFVIGS
                     VSLIFWTLTLLTTIKYVVIALNADNHGEGGIFSLYTLVRKGGKYLIIPAMIGGAALLA
                     DGVLTPAVTVTTAIEGLRGIPQFFDRFGNNQNVIVIITLVIIFVLFMVQRFGTDIVGK
                     AFGPIMFAWFTFLGVMGLMNFSQDWTVIRALNPYYAIQLLFSADNKLGLFILGNIFLA
                     TTGAEALYSDLGHVGKRNIRLSWPYVKICLVINYFGQAAWLLNVYQNPEAQQIKNLNP
                     FFQMMPQSWIVIGVAFATVAAVIASQALITGSFTLVSEAIKLKLLPRLKIMYPGNSIG
                     QMYIPAVNLILWIACSLVVVTFRTSHHMEAAYGLSITVTMLMTTALLYFYLIQNGHSR
                     WLAYLVTFFFGAIEVVFFISSVVKFFRGGFVAVLIGLIILVVMFIWEQGNIIRESSTE
                     DVSLRDYIPQLRELRDDTSLPIYQTNVVFLVPDMAEDKVGRQFIYSILDKRPKRARVY
                     WFVHVEVTDEPYTKEYQVDMMDTDFIVQVNLFLGFRVQQEINVYVRQVIHDLMKQGRL
                     PKQPQRYSLTPGREVGDFQFVLIDEVVSNVTTLGKWQRQIMQAKLAIKKIATSPETWF
                     GLEYSEVKHETVPLIIGNTRKTWLKERL"
     gene            complement(3698..3964)
                     /locus_tag="LLC22_002060"
     CDS             complement(3698..3964)
                     /locus_tag="LLC22_002060"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376985.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5435317.1"
                     /translation="MLNFLWSLFIGGILGLIAGAILGKEVPGGVSGNIIIGFLGSWLG
                     EFLLGPLGPELGGFYLIPALLGAIFCLALYSFVARRIRERPKKE"
     gene            complement(4474..6600)
                     /gene="pnp"
                     /locus_tag="LLC22_002061"
     CDS             complement(4474..6600)
                     /gene="pnp"
                     /locus_tag="LLC22_002061"
                     /EC_number="2.7.7.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyribonucleotide nucleotidyltransferase"
                     /protein_id="HBK5435318.1"
                     /translation="MSEKQVFKTTWGGRPLQIEVGQLAKQANGAVLVRYGDTVVLSAA
                     VASKEAKDTDFFPLTINYEEKMYAAGKIPGGFIKREGRPSTEATLTARLIDRPIRPMF
                     AEGFRNEVQVTNIVMSVETDCSPAMAAMLGSSLALSISDIPFDGPIAGVEVGRVNGEY
                     VLNPTVEQAEQTDIELTVAGTKQAINMVESGAKEVSEEDMLGALLFGFDAIKELVAFQ
                     EEIVQAVGKEKMEVTLLQVDEVLKKEIFDASYATMKAAVMTEEKLAREDNIEQVKIDI
                     REAYAEKFAGHEDEDHLLKEVKQITEDLEKDVVRELITIDKIRPDGRKLDEIRPLSSE
                     VSLLPRVHGSGLFTRGQTQALSACTLAPLGEHQIIDGLGVEVSKRFIHHYNFPQFSVG
                     STGRAGSPGRREIGHGALGERALAQVIPSEEEFPYTIRLVAEVLESNGSSSQASICAG
                     TLALMDAGVPIKAPVAGIAMGLVSDGENYTILTDIQGLEDHLGDMDFKVAGTKDGITA
                     LQMDIKIQGITEQILTEALTQAKQARMEILEELTSTIAAPREELSQYAPKIEMIQIEP
                     AKIKDVIGKGGDTINGIIDETGVKIDIDQDGKVSIASADAEMIKKAIKIIEDLTKEVK
                     VGEVYLGKVVRIEKFGAFVNLIKGKDGLVHISQLANDRVNKVEDVVKLGDEILVKVTE
                     IDKQGRVNLSRKAMLNEDGSTKNEEK"
     gene            complement(6788..7057)
                     /gene="rpsO"
                     /locus_tag="LLC22_002062"
     CDS             complement(6788..7057)
                     /gene="rpsO"
                     /locus_tag="LLC22_002062"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S15"
                     /protein_id="HBK5435319.1"
                     /translation="MAISKERKNEIINEYARHEGDTGSPEVQIAVLTEEINHLNEHAR
                     VHKKDHHSYRGLMKKVGHRRNLLAYLRKTDVQRYRELIKRLGLRR"
     gene            7308..7871
                     /locus_tag="LLC22_002063"
     CDS             7308..7871
                     /locus_tag="LLC22_002063"
                     /EC_number="3.5.1.88"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016623744.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide deformylase"
                     /protein_id="HBK5435320.1"
                     /translation="MITMDDIIREGNPTLREVAKEVSLPLSEEDISLGKEMLEFLKNS
                     QDPIKAEELHLRGGVGLAAPQLDISKRIIAVHVPSPDPEADGPSLSTVMYNPKILSHS
                     VQDACLGEGEGCLSVDREVPGYVVRHAKITVSYYDMNGEKHKIRLKNYESIVVQHEID
                     HINGVMFYDHINDQNPFALKEGVLVIE"
     gene            complement(8124..8645)
                     /locus_tag="LLC22_002064"
     CDS             complement(8124..8645)
                     /locus_tag="LLC22_002064"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription repressor NadR"
                     /protein_id="HBK5435321.1"
                     /translation="MIEGETRRKQIMQTLANTEKPVSASKFAKTFGVSRQIIVGDIAL
                     LRAAGKSIVATARGYILETEETNTGHISKIAVQHGKDQTEEELRLIVENGGEIIDVIV
                     EHPLYGELAGTLHIKTPQDIDSFMRRYQKSNATLLSELTGGIHLHTIRYPEKHMLKNI
                     KQKLAEAGILYEG"
     gene            complement(8648..9490)
                     /locus_tag="LLC22_002065"
     CDS             complement(8648..9490)
                     /locus_tag="LLC22_002065"
                     /EC_number="5.4.99.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chorismate mutase"
                     /protein_id="HBK5435322.1"
                     /translation="MTEFKTEKEKMIAGELYFANDPELVADRMFARSQSQIINQAESA
                     ELRSQLLKETFGRTGKKIYMEPVINFDYGYNIFVGENFYANFNCTFLDVSTIEIGDNC
                     MFAPNVQLYTAKHPLHPVKRNSGLEYAKPIKIGNNVWLGGGVIVTPGVTLGDNVVVGA
                     GSVVTKSFPDNVVIAGNPARIIKTVEEELTEESLETLRHKIDMIDRELVALLEKRMDT
                     VTKIGQVKKEENQAVYDAKREQQVLDKVVSLLKNKGYKETITDTYVDLMKHSREYQNK
                     MKEE"
     gene            complement(9483..10208)
                     /locus_tag="LLC22_002066"
     CDS             complement(9483..10208)
                     /locus_tag="LLC22_002066"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327537.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent protein deacylase"
                     /protein_id="HBK5435323.1"
                     /translation="MKQLTVDEAAKEILAYQQITFLTGAGVSTPSGVPDYRSLSGIYH
                     GMEQPEYLLSHQAMVNEPDKFYQFVKKIYHPEAKPNIIHLEIAHLAKEKNVWVVSQNI
                     DGLHAKAKSPQLVNFHGSLYQCHCRKCQQTVDWKEYLHSDKHQACGGQIRPDIVLYGE
                     GFQDGVMEQAAYAVSQAELIVIVGTSFQVHPFCDLVQFRQPSAKILVINQTPVYLAEP
                     YTFIQEDGAVVFKKIQELGADYD"
     gene            10384..10680
                     /locus_tag="LLC22_002067"
     CDS             10384..10680
                     /locus_tag="LLC22_002067"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339483.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435324.1"
                     /translation="MLPFFIYWGVILACIAWLALSVYFSVFYLVRKENGNLWAFALFN
                     VIAAIVLAITLAVYRTWGWGITQYSSLIYLILAIYGVVVLLQAILGREPKKAAA"
     gene            11248..12840
                     /locus_tag="LLC22_002068"
     CDS             11248..12840
                     /locus_tag="LLC22_002068"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327538.1"
                     /note="The N-terminal region of this protein, as described
                     by TIGR01726, is a three transmembrane segment that
                     identifies a subfamily of ABC transporter permease
                     subunits, which specificities that include histidine,
                     arginine, glutamine, glutamate, L-cystine (sic), the
                     opines (in Agrobacterium) octopine and nopaline, etc;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK5435325.1"
                     /translation="MKKNMVSVAVLFAFVFSLFSVGSLANADEKTPSDEFRVGMEAGY
                     APFNWSQQTDENNALPIQGQNSYAGGYDVQIAKKVADGLGKKLVIVQTKWDGLAPALQ
                     SGKIDAIIAGMSPTAERRKEIDFTDPYYESQLVVVVQKDSKYAKAKSLADLSGAKITA
                     QLNTFHYTVIDQIPDVQKQQAMDNFSAMRTALASGMIDGYVSERPEGVTATSVNKDLE
                     MLEFSGADGFQTNPEDVQISVGMRKGDPDIQKVNQILSGISNDERTKIMDQAVKDQPA
                     ATDSEEKPGIISDFTTIWKQYGNMFLRGAGLTLFIALIGTVVGTTLGLLIGVFRSVPE
                     SGNALTRFFQKIGNALLSIYVEVFRGTPMMVQAMVIFYGLALAFGISLNRTIAALFIV
                     SLNTGAYMTEIVRGGIFAVDEGQFEAAQAIGMTHGQTMRKVVIPQVLRNILPATGNEF
                     VINIKDTAVLSVIGVADLFFQGNSASGANFQFFQTFTIVGIIYLVMTFTITRILRAVE
                     KKIDGPSAYTKLEEIDNSNLQE"
     gene            12853..13593
                     /locus_tag="LLC22_002069"
     CDS             12853..13593
                     /locus_tag="LLC22_002069"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid ABC transporter ATP-binding protein"
                     /protein_id="HBK5435326.1"
                     /translation="MNEKIIEIKHLRKSFGENEVLKDISVTVNKGEVVTIIGSSGSGK
                     STFLRCINLLEKPTGGEIIYNGENVLAPKYNLPKYRTNLGMVFQSFNLFNNMNVLENC
                     MSGQTTVLKRDKETAKKVAIENLEKVGMDRYIEAKPAQLSGGQKQRVAIARALSMNPD
                     VLLFDEPTSALDPEMVGEVLNTIKDLAHTGLTMLIVTHEMEFAKDVSDRVIFMDKGVI
                     AEEGTPEDIFVHPKEERTKEFLSRILNA"
     gene            13761..15110
                     /locus_tag="LLC22_002070"
     CDS             13761..15110
                     /locus_tag="LLC22_002070"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5435327.1"
                     /translation="MNEEQELQRGLKNRHVQLISIGGAIGTGLFLGSGKSIQLAGPSI
                     LLAYLITGCICFFIMRALGELLLSNTNNHSFLDFVAEYLGKKAAFITGWTYWFCWVSI
                     AMADLTAIGMYVRYWAPGVPQWLPELIALGLLLCLNMVAVSLFGELEFWFALIKVVAI
                     IAFILVGAYMILTHYTTDIGTASITNLWSHGGFFPTGAKGFILAFQMVTFAFAGIELV
                     GLVAGETENPEKVLPEAINNIPIRIILFYLGSLFVIMAIYPWNSLNPDNSPFVEVFSE
                     IGITIAASLINLVVLSAAASACNSAIYSTGRMLRSLAQEGSAPKKFKKLTTHHVPGNA
                     LTFSTIVIFISVILNYVMPSEVFTLVSSIATTCFLFIWSMLVYTHMKYRKSILGKKAH
                     SFKMPLYPFSNYLVFLYMAFVCVVLFLGKDTRIALLLTPVWFLLLLLIYHMKYERKK"
     gene            complement(15238..15828)
                     /locus_tag="LLC22_002071"
     CDS             complement(15238..15828)
                     /locus_tag="LLC22_002071"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376975.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1211 domain-containing protein"
                     /protein_id="HBK5435328.1"
                     /translation="MTKSRLEAFTDGVVAIVLRVIVLEIKIPNTSSFHSLWVIRNTLL
                     AYTISFIFVAVIWVNHHRIFQMAERINYRVVWSNIFLLFWLTLCPSVTSWVGRNPEAF
                     WPEMAYVLVYTMWSFSFGILMRQIMKANKPDSHVVRVLSKDRRSLISMMINLCLIAGV
                     FFVPLIGLFGRFFVSGIWIFSYKKADAYYQRLFPGK"
     gene            15975..17327
                     /gene="brnQ"
                     /locus_tag="LLC22_002072"
     CDS             15975..17327
                     /gene="brnQ"
                     /locus_tag="LLC22_002072"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328038.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBK5435329.1"
                     /translation="MTKKLSFKDYLFIGSMLFGLFFGAGNLIFPVHLGQEAGAATFWA
                     NLGFLVTGIGLPFLGVIAIGVSKSSGVYELAKRINQTYAMVFTILLYLVIGPFFALPR
                     LATTSFEIGLAPFIDPSRQTLYLAIFSIVFFVLAWWFSRKPTKILDYVGKFLNPAFLV
                     LLGALLLLAFLNPLGSVNQAPIQPNYQEHAFFTGFTQGYNTLDALAALAFGIIIVTTI
                     QNMGVTKPAEIAKDTIKSGAISIILMGIIYTLLAYLGAMSLGSFALSENGGITLAQIA
                     DHYLGTYGSILLAFIVILACLKTGIGLITAFAETFTDLFPQRNYAFFVALASILPCLA
                     ANVGLTNIIQFSLPVLMFIYPLAMTLILLVLVGPLFKQRTAVYRMTTYFTLIASIFDG
                     LNACPETIKQTPIVQNLLYVAESYLPFFKLGMGWIVPAVIGFVIGLIWSFAKKEEVAD
                     "
BASE COUNT         5094 a         3596 c         3397 g         5655 t
ORIGIN      
        1 tgtgacaaaa aatgtcacag ccttttttct tttattctat ttttctttcc gtggactcta
       61 ctttgaaata atcgatatgt gcatgctggt attctaatac cgtgaaacgg aatgatgcaa
      121 tctcaatgat tgttcctgct tttatttctt tatatcggct agaagcaaag cccgcaagtg
      181 tagtaaaatt cgtttcttca aactctggaa tctctacatg aaaataacgc tggaaatcat
      241 ctaatgttag tttgccggag atgatataag agccatctga ctgttccgct atcaatgctt
      301 cgtccaaatc tgtctcatct cggatttccc cgacgatttc ttctaaaata tcttcaatcg
      361 tcactaagcc gcttgtccct ccgtattcat cttttaagat agcaatatgc tttccctttt
      421 ttcgcatgat cgtcaataat ttttttatag ggatcgtttc agttgttacg atcggctctt
      481 caatcaactg ttctactgtc agctggtcat ctttataaga ttgcttgatc aaatctggca
      541 aggtgacata acctaaaaca ttgtcttttg attctaagat aaccggatag cgagtatgtc
      601 cttgttcaat cgaagctttt atcgcttctt tgacggtttc tgaagcttcg aatacttgca
      661 tggacgtacg gtctacttgt atatcttttg ccaaggtatc atcaaattca aacacgtttt
      721 ccaaataatg atattcttct ttggtcaact ctcctttttc ataagaattc aatgcgacta
      781 atgtcagctc ttcttgagac aatgtctctt ctccttcaga tacgagacgc acacctaata
      841 gcttccctag ccctgcagct gaatgattca atacccaaat aaaaggaaac attactttat
      901 aaaaataatg aagtggttta actacgaaca agacgacctt ctccgtattg acgatactat
      961 agctcttagg aagcagttcg ccaataacca catcgatata cgtaactaaa ataaatccca
     1021 gcgccacaga gattgtactg ctaatagccg aactaaaagg tagtttaccg atcactggtt
     1081 ctagtaaagc cgcgacagat ccttcaccga cccacccgat gatcaaaccg gttagcgtaa
     1141 ttcctaattg actagctgat aaatagttat ctaaatggtg tgtaacatga agagctagct
     1201 tggcgttctt tacattttcc ttttctagtt gttccaatct tgatcgtctg attttcacta
     1261 aagcaaattc acttgctaca aaaaatgaag taattgcaat catcaaaaat aaaataatga
     1321 aattgataac catattctcc cgcctttctc tttttctatt gtaccctttt tctacaaaaa
     1381 gattgaaaat aatgcgtatt catatttagg aataaaaaag gagatgcggc atttttcagc
     1441 cacatctcct tatcacttca aaatcattgc gttacttgtt gctaaacagc tttttcatga
     1501 cctctgataa acggtgttca agtagctgac attcgacatt agttcaggtc aaagcgctac
     1561 tttcacaacc gctctttcaa ccatgttttc cgagtatttc caatgataag cggaacagtt
     1621 tcatgtttta cttcgctgta ctctagccca aaccatgttt ctggcgaggt agcgattttt
     1681 ttgattgcca gttttgcctg catgatttga cgttgccatt ttcctagagt tgtcacattg
     1741 gaaactactt catcaatcag gacaaattgg aaatcgccaa cttctcgccc tggtgtcaga
     1801 gagtatcttt gtggctgttt tggcaaacgg ccttgtttca tcaaatcatg gatgacttgg
     1861 cgaacatata cgttgatttc ctgttggacc ctgaaaccta agaacagatt cacttggaca
     1921 ataaaatcag tgtccatcat atctacttga tattctttcg tatatggctc atccgtcact
     1981 tccacatgaa caaaccaata gactcgtgct cttttaggcc gtttatctaa aatcgaatag
     2041 atgaactgtc ggccaacttt atcttcagcc atatcaggaa ccaagaagac cacatttgtc
     2101 tgatagattg gtaaagaagt atcatcacgt aattctctaa gctgcgggat ataatctctc
     2161 aaagacacat cctcggttga cgattcgcga ataatgttcc cttgttccca aataaacatc
     2221 acgactaaga tgatcaaacc aatcagaacg gctacaaaac cgcctcggaa gaatttgaca
     2281 acacttgaga taaagaaaac gacttctatc gcaccgaaga aaaaggtaac taaatatgca
     2341 agccaacgag aatgcccatt ttggataaga taaaagtaaa gcagtgctgt tgtcatcaac
     2401 atcgtcacag tgatcgatag accgtaagca gcttccatat gatgagacgt tcggaatgtg
     2461 acaaccacta gagaacaggc gatccataaa atcagattga ctgctgggat atacatttgc
     2521 ccgatactgt tcccaggata catgatcttt aaccgaggca gcagtttcaa cttgattgct
     2581 tctgaaacta gcgtaaacga acctgtaatc aatgcttgcg aagcaatgac tgcagcgact
     2641 gttgcaaaag caacgccgat cacgatccaa ctttgaggca tcatttggaa gaatggattc
     2701 aggttcttga tttgctgtgc ttcagggttt tgataaacat tcaacaacca cgcagcctgc
     2761 ccaaaataat tgataaccaa acaaattttg acgtaaggcc agctcagacg aatatttcgt
     2821 ttgccgacat gtccaagatc ggaataaagc gcctctgcac ctgtcgtagc caggaaaata
     2881 tttccaagaa tgaacaagcc taatttgtta tctgcactaa aaagcagctg gatagcataa
     2941 taaggattca gtgcacggat aactgtccag tcttgactga agttcattaa tcccattacg
     3001 cctaaaaaag taaaccaagc gaacatgatt ggtccgaatg cttttccgac aatatctgta
     3061 ccaaagcgtt ggaccatgaa taaaacaaaa ataataacta aagtgataat gacgatcacg
     3121 ttctggttat taccgaaccg gtcaaaaaac tgcggaattc ctcgcaagcc ttcaatcgca
     3181 gtcgttaccg tcacagcagg ggtcaatacc ccatctgcta gtaaggcagc tcctccgatc
     3241 attgcaggaa tgatcaaata tttcccacct tttcggacaa gtgtgtagag tgagaaaatt
     3301 ccaccttcac catggttatc tgcattcaat gcaatcacga catatttgat tgttgtcagt
     3361 agagtcaatg tccaaaaaat caatgagact gatccgataa caaaatcagg attgattcct
     3421 gacaatccgc cattatcttc aacaatcgat ttcataacgt aaagcggact tgtcccgatg
     3481 tctccgtaga cgactcccat cgctacaagc aggccagcca ttgatatctt tttggtattg
     3541 tgcgttgttg ccacgttttt ccctcatttc ttgttatatg gatatccttt aggtaagctt
     3601 gaatgataga tgatattctt atccatgaca cccgctttcc taaattgctt ctaattatcc
     3661 aagtaacaca ctgaagtgtc aacttatttg aataaaatta ttctttcttt ggacgttctc
     3721 tgatacgtct tgccacaaat gaataaagag caaggcaaaa aattgcaccc aataatgctg
     3781 gtatcaaata aaaaccgccg agttccggtc ccagtggtcc tagtaaaaat tcgccgagcc
     3841 aactacctaa aaaaccgata atgatatttc cagatacgcc tcccgggact tcctttccta
     3901 aaattgcgcc agctatcaaa cctaatatac cgccgataaa taacgaccat aaaaaattca
     3961 gcatctcctt tccctccttt atccatattt ctcactttta ttttacgctt tattcagaag
     4021 gactccaaaa atatgcgcca agaaactcca gaaaaaaaga agttgtaaca aaagtgttca
     4081 gcttatttcc gtagaagctg cttctggaac accgtgaatc agaggttgtg aaatcagcgg
     4141 tttgacctga gtattagaga aacaaacgga aaaatagttc ctcatatttt gccgtttttt
     4201 gagctaatat cgagggacag ctgattgaac atcgtttatt ggagaggttg taaaaaagct
     4261 gttctgcatc aagtaataag aacagccaag taaaaacagc tcctaatgtt tttaacttgg
     4321 ctggacttat taccgcagat gcaagctttt gaacaccgtt tattcgaaaa aaaaggactg
     4381 tgacacggct tttgtcacag tccccttttt tcgaataatt attgtccccc tgtcaccttc
     4441 acgatcacaa gtacattatt cctatgaatt aaattatttt tcttcatttt tcgttgaacc
     4501 atcttcgttc aacattgctt ttcttgacag atttacgcgt ccttgtttat cgatttcagt
     4561 tactttcaca aggatctcat cacctagttt aacaacatct tcgactttat tgacacgatc
     4621 gtttgctaat tgggaaatat ggacaagtcc atcttttcct ttgatcaagt tgacgaatgc
     4681 accgaatttt tcgatacgga caactttccc tagataaact tcaccaactt tgacttcttt
     4741 ggtcaaatct tcgatgatct tgatagcttt tttgatcatt tctgcatcag ctgaagcaat
     4801 acttactttt ccatcttgat cgatatcgat tttcacacca gtttcatcga tgattccgtt
     4861 gatcgtatcg ccgcctttac cgataacatc tttgatttta gcaggttcga tctggatcat
     4921 ttcgattttt ggtgcatatt ggcttaattc ttcacgtgga gcagcaatcg ttgaagtcaa
     4981 ttcttctaag atttccatac gtgcttgttt tgcttgagtt aatgcttcag ttaggatttg
     5041 ttctgtgatt ccttgaatct tgatatccat ctgtaaagca gtgataccat cttttgtacc
     5101 ggcaacttta aagtccatat cgccaagatg atcttccagc ccttggatat cagttaggat
     5161 cgtatagttt tcaccatcag aaacaagtcc catcgcaata ccggcgactg gcgctttgat
     5221 tggtacacct gcatccatca atgctaatgt gccagcacag atacttgctt gggaagaaga
     5281 accatttgat tccaatactt ctgctactaa acggatcgta taaggaaatt cttcttctga
     5341 agggattact tgtgctaacg cacgttcacc taatgcgcca tgtccgattt cccgacgccc
     5401 tggagagcct gcacgtcctg tagaaccaac agaaaattga gggaaattgt agtggtggat
     5461 gaatcgtttg ctgacttcca cccctaaacc atcaatgatt tggtgctctc ctagaggtgc
     5521 gagtgtacaa gctgataaag cttgtgtttg tcctcgtgtg aacaaacctg atccatgtac
     5581 acgtggcaat aagctgacct ctgatgacaa tggacggatt tcatccaatt tacgcccgtc
     5641 aggacggatc ttatcgatgg tgatcaattc acgtacgaca tctttttcaa gatcttctgt
     5701 gatttgttta acttctttca acaagtgatc ttcatcttca tgacctgcaa atttctcagc
     5761 ataagcttcg cggatatcga tcttcacctg ctcgatatta tcttcgcgag caagtttttc
     5821 ttcagtcatt actgctgctt tcattgtagc gtaagaagca tcaaagattt cttttttcaa
     5881 tacttcatca acttgcagta aagtcacttc cattttttct ttccctactg cttgaacgat
     5941 ttcttcttgg aaagcaacta actctttgat agcgtcaaaa ccaaacagca atgcaccaag
     6001 catgtcttct tctgaaactt ctttcgcgcc gctttcaacc atattgatgg cttgtttcgt
     6061 tccggcaaca gtcaattcga tatctgtttg ttctgcttgt tctactgttg gattcaagac
     6121 gtactcgcca tttacacgac caacttctac gcctgcgatt gggccgtcaa atgggatatc
     6181 tgagattgat agtgctaaag aagaacctag cattgctgcc atagctggcg agcagtctgt
     6241 ttctacactc atcacgatgt tcgttacttg gacttcatta cggaagcctt ctgcaaacat
     6301 cgggcgaatt ggacggtcga tcaaacgggc agtcaatgtt gcttccgtac ttggacggcc
     6361 ttctcgtttg atgaaacctc cagggatttt ccctgctgca tacatttttt cttcataatt
     6421 gatcgttaat gggaaaaagt ctgtatcttt tgcttcttta gaggccacag ctgcacttaa
     6481 gactactgta tctccataac ggactaaaac ggctccgttt gcttgttttg ctagctgacc
     6541 gacttcgatt tgtaagggac ggccgcccca tgtcgttttg aatacttgtt tttctgacat
     6601 aacttctcct tttccttctc gtgaaagcaa gacgctacta aacaaatgaa aactgccgaa
     6661 agccgtcttt tgagcagctt tcatttggtt agtaggagtc catctagctt gatcacggaa
     6721 ttttacttaa ttgatatacg agtaaaaaaa gtgagattca tgtgaatccc actctttttg
     6781 actaaaatta acgacgcaag cctaaacgtt tgatcaattc gcggtaacgt tgaacgtcag
     6841 ttttacgtaa gtaagctaac aagttacggc ggtgaccaac ttttttcatt aggccgcggt
     6901 atgaatgatg gtcttttttg tgcacgcgtg catgttcatt caagtggttg atttcttcag
     6961 ttaatacagc gatttgtact tctggagaac cagtatcccc ttcatggcga gcgtattcgt
     7021 tgatgatttc attcttgcgt tcttttgaaa ttgccatttc tttcacctct ttcgattatt
     7081 cccctgcgac tgagtaaaac gttggtgatt cgcttaacca agtggcaggt catgtgccta
     7141 gagcacacag ctatacttta cctgaaaccg ggttgaaaat caagtagtta atcattaaga
     7201 aaaggtagtt ttcaaacaat cttactacta cttttccatt tttgtggtaa actataatgc
     7261 gaaaatagac ttgaaacaca gtcttttaag aaaggggtac atattccatg attacaatgg
     7321 atgatatcat tcgtgaagga aatccgacct tacgcgaagt tgcaaaagaa gtttctcttc
     7381 cattaagcga agaagatatc tctttaggaa aagagatgct tgagttctta aaaaacagcc
     7441 aagatccaat caaagctgaa gaactacact tacgaggcgg tgttggctta gctgctcctc
     7501 aattagatat ttctaaaaga atcattgctg ttcacgtacc aagtcctgac ccagaggcag
     7561 atggaccttc tctaagtact gttatgtata atcctaaaat tttgagccat tctgttcaag
     7621 atgcttgttt aggggaaggt gaaggctgtt tatctgttga tcgagaagta ccaggatatg
     7681 ttgttcgcca tgccaaaatc actgtgtctt attatgatat gaatggtgaa aaacacaaga
     7741 ttcgtttgaa gaattatgaa tcgatcgtcg ttcaacatga aatcgaccat atcaacggtg
     7801 tgatgttcta tgaccacatc aacgatcaaa atccatttgc actaaaagaa ggcgtattgg
     7861 tgatcgagta gagaattggc aggttccttc gatactatgc tacaagaaag ctttataaaa
     7921 aaggggagtg ctcaaaagct gcacttccct tttttatgtt tctccactaa tcgaaattta
     7981 gatagacatc tagaaatcgc aattccaaaa aattctgtgt attggatacg catcttttct
     8041 tattttttct tatttcttcc atatgggtgt ttatctcaga gatgatagaa tagtttctag
     8101 gataaaaagt agcagctacg atgttatcct tcgtagagga ttcctgcttc agctagtttt
     8161 tgtttgatgt ttttcagcat atgcttttct gggtagcgga tcgtatgcag atggatgccg
     8221 cctgttaatt cggataacaa agtagcatta cttttttgat aacgtctcat aaaggaatcg
     8281 atatcttgtg gcgttttgat gtgcaaagtt cctgctaact caccgtaaag gggatgttcc
     8341 acaattacat caatgatttc accaccattt tcaacgatta gtctcagttc ttcttctgtt
     8401 tgatcttttc catgctggac agcgatttta ctgatgtgcc cagtattggt ttcttctgtt
     8461 tcgaggatat aacctcttgc tgttgccacg atacttttac ctgcagctcg tagtaaagca
     8521 atatcgccta caatgatctg acggctgact ccaaaagttt tcgcaaactt gctagcactc
     8581 actggttttt ctgtatttgc caaggtttgc atgatttgtt ttcgccgtgt ctctccttcg
     8641 atcacactta ttcctccttc attttgtttt ggtattcgcg cgagtgtttc atcaaatcaa
     8701 catacgtgtc tgttattgtt tccttatatc ccttattttt cagcagacta acaactttat
     8761 ccaatacttg ctgctctctt tttgcatcat aaactgcttg gttttcttct tttttcactt
     8821 gtcctatttt agttaccgta tccattcttt tttctaataa agcaaccaac tctcgatcga
     8881 tcatatcgat cttatgacgt aatgtttcaa gagactcttc tgttagttct tcctctactg
     8941 tcttgatgat acgagcagga tttcctgcaa tcactacatt gtcgggaaaa gatttggtca
     9001 caaccgaacc tgcgccgact actacgttgt cccctagagt gacacccggc gtgacgataa
     9061 ctcctccgcc taaccaaaca ttattaccga ttttaatggg ttttgcgtac tccagaccgc
     9121 tgttacgttt cactggatgt agtggatgct tcgccgtgta aagctggaca ttcggagcga
     9181 acatgcagtt atcaccgatt tcaatcgtgc tgacatctaa aaatgtacaa ttgaaatttg
     9241 cataaaaatt ctccccaaca aatatattat atccgtaatc aaaattgata actggctcca
     9301 tatagatttt tttccctgta cggccaaaag tctctttcaa caattgggat cgcagttccg
     9361 ctgattctgc ttggttgatg atttggcttt gacttcttgc aaacatacgg tcggcaacca
     9421 gctcaggatc attggcaaaa taaagctcgc ctgcaatcat tttttctttt tcggttttga
     9481 attcagtcat aatctgctcc taattcttgt atttttttga aaacaaccgc tccgtcttct
     9541 tgaataaacg tataaggctc cgctaaataa acaggcgttt gattgattac taagattttg
     9601 gctgacggct ggcgaaactg taccagatca caaaacggat gaacttgaaa actcgttcca
     9661 acaatgacga tcagctctgc ttggctgacg gcataagccg cctgctccat gactccatct
     9721 tgaaaccctt caccatataa cacgatgtct gggcgtattt gtcctccgca tgcttgatgt
     9781 ttgtcgctgt gaagatattc tttccagtct accgtttgtt gacattttcg acaatgacat
     9841 tgatacagac tcccatgaaa attgacgagt tgcgggcttt tagcctttgc gtgcaaaccg
     9901 tcgatgtttt gggaaacaac ccaaacattt ttttctttcg ctagatgtgc tatttccaaa
     9961 tgaatgatat tgggttttgc ttcaggatga taaatctttt tgacaaattg atagaattta
    10021 tccggttcat tcaccattgc ttgatgactc agcaagtatt ccggctgctc catcccgtgg
    10081 tagattcctg acaaagatcg atagtctggc actccagaag gtgtggatac ccctgcaccg
    10141 gtcaaaaatg taatttgctg ataagctaat atctcttttg ctgcttcgtc tactgttaat
    10201 tgtttcatgt tttgtcacct cactttccat tatagcccat actcgaacaa atttattgtt
    10261 gaaaagtcag aaaaatggga ataaaaaagt gttatgggca tttgagcaat ttatcacaat
    10321 gttcactgac aaaagaatga aaacgtgtta caatactgct gtataaaagt gaggtgaatc
    10381 gatatgttac cattctttat ttattggggc gttattctgg cttgtatcgc ctggttagcg
    10441 ttaagcgttt atttctctgt tttttatctt gtacgcaaag aaaatggaaa tctttgggct
    10501 tttgctttat tcaacgtgat tgccgcaatt gttttagcca ttacattagc cgtatatcga
    10561 acatggggct ggggaatcac ccaatactca agtttgattt atctaatatt agccatttat
    10621 ggcgtcgttg ttcttttgca agcgatccta ggacgtgagc caaagaaagc ggcagcttaa
    10681 atgatcgaga tggaactgga cacaggaaat tttctgttct agttcttttt ttattgtatt
    10741 acatacattt ttgtgtataa ttatactatc gtttgcaatg gatagatgat tcacattttg
    10801 attgtttttt cggtaaaagt aaagatttct atatttatca gtattttttc aaaaaccagc
    10861 agttatagat tgacaaagcc tctcgagtat cgtaaacttt ttttgtataa ataactgaat
    10921 acgagatgcc tcaatcaatg aggtagaggt cgcgagaatc attaaccctg tggagtgaag
    10981 caaacatgga gaagcaggaa tagggaggat cgccgaaatg tgcacttttt tgcttggagt
    11041 gtatgttggg acgcaagtta agagcttgcg gactgtctta gcagtgatgc taagttgcgc
    11101 tatgttttgt gagaggttta tcaccttatg gaattttagc ggccttttta tatctataaa
    11161 tcggtcgctt tttatttttt cagataaagc tttaccgcat ttcatctaga ccgctcgtgt
    11221 atcatataat cagaaaggga gaaaaaaatg aaaaaaaata tggtttcagt tgccgtacta
    11281 tttgcttttg tcttctcact attcagtgtg ggatctctgg caaatgcaga tgaaaaaaca
    11341 ccgagcgatg agtttcgcgt aggtatggag gctgggtatg cacccttcaa ctggtctcaa
    11401 caaacagatg agaataatgc cttgccaatt caaggccaaa atagttacgc cggcggttat
    11461 gatgttcaaa tcgctaaaaa agtagcagat ggtttaggga aaaaattagt catcgtccaa
    11521 acgaaatggg atggtctggc tcctgccctt caatcaggca agatcgacgc gatcatcgcc
    11581 ggaatgagcc ctactgctga acgacgaaaa gaaattgatt ttaccgatcc ttattacgaa
    11641 tcacaattag tagtagtagt tcaaaaagat agcaaatatg caaaagcaaa aagtttagca
    11701 gatctttctg gagcaaagat cactgctcag ttaaatacat tccactatac tgtgatcgat
    11761 cagataccag atgtgcagaa acaacaagca atggataatt tctcagcaat gagaacagct
    11821 ttagcttctg gaatgatcga tggttatgtc agcgaacgtc cggaaggtgt aacggcaact
    11881 agtgtgaaca aagacttgga aatgcttgaa ttcagcggtg cagatggctt ccagacaaac
    11941 ccggaagatg ttcagatttc tgttggtatg cgtaaaggcg acccggatat ccaaaaagta
    12001 aaccagattc tttctggcat ctctaacgat gaacgaacca aaattatgga ccaagcagtc
    12061 aaagatcagc ctgctgcaac tgatagtgaa gaaaaacctg gcatcatttc tgatttcact
    12121 acgatttgga aacaatacgg caatatgttc ttacgaggtg ctggacttac cttgttcatc
    12181 gcattgatcg ggacagttgt cggtactaca cttggattac tgattggtgt cttccgttcg
    12241 gtacctgaat caggaaatgc actgactcgc ttcttccaaa aaatcggaaa tgcacttctt
    12301 tctatctatg tcgaagtatt ccgcggaaca ccgatgatgg tacaagcaat ggtcatcttc
    12361 tacggtctgg cactcgcttt tggcatttca ttgaaccgaa cgattgccgc tttgtttatt
    12421 gtctctctca atactggagc ttacatgaca gagatcgttc gtggggggat ttttgcagta
    12481 gatgaagggc agttcgaagc tgcgcaagcc attggtatga cccatggcca aacgatgaga
    12541 aaagttgtta ttccacaagt tttacggaat atcttgccag caacaggaaa tgagtttgtt
    12601 atcaatatca aagatacagc agttttaagt gtaatcggcg tagctgattt gttcttccaa
    12661 ggaaactctg cttccggtgc gaatttccaa ttcttccaaa catttacgat cgtcgggatc
    12721 atctacttag tcatgacctt tacgatcacc agaatcctgc gggcggtaga aaagaaaatc
    12781 gatggtcctt cagcttatac caagcttgaa gaaatcgaca attcaaattt gcaggaataa
    12841 ggaggaagaa tcatgaatga aaaaattatt gaaatcaaac atctaagaaa aagcttcggt
    12901 gaaaatgaag tattgaaaga tatcagcgta acagtcaata aaggtgaagt tgtgacgatc
    12961 atcggttctt ccggttctgg taaatctact ttcttgcgct gtatcaattt actggaaaaa
    13021 ccaacaggcg gcgagatcat ttataatgga gaaaatgtat tagctcctaa atataattta
    13081 cctaaatatc gaacgaatct aggtatggtt ttccaatcct tcaacctgtt caacaatatg
    13141 aatgtcttgg aaaactgtat gtctggtcaa acaactgtcc tgaaacgaga taaagaaact
    13201 gccaaaaaag tagcaatcga aaatctggaa aaagttggta tggatcgtta tatcgaagcc
    13261 aaaccagcac aattatctgg tggacagaaa cagcgtgtcg caattgctcg ggcattatca
    13321 atgaatccag atgtattgct attcgacgaa cctacttcgg cgttagaccc tgaaatggtt
    13381 ggcgaagtgc ttaatacgat caaagactta gcacatactg gcttgacaat gcttatcgtg
    13441 acgcatgaga tggaatttgc aaaagatgta tctgaccgtg tcatttttat ggataaaggt
    13501 gtgattgcag aagaaggtac accagaagat atctttgtcc atccgaaaga agaacgtaca
    13561 aaagaattcc tttcacgtat tttaaatgct taggatcaat agctgattgg gacaaagagc
    13621 tgcggtgttt accgcagttc ttttttatga attactcata aaaggtaaat ttctgaaaat
    13681 tttggaatct tagttgtgtt tttcagaaaa ctctcttaat atggaagtaa ttaaactttt
    13741 ttagttagga tgatttaaaa atgaatgaag agcaagaact gcagcgtgga ctgaaaaata
    13801 gacatgtcca actgatttct attggcggag cgattggaac ggggttgttt ttaggttccg
    13861 gaaagtctat ccagctagct ggcccttcga tattgctcgc ctatcttatt actggatgca
    13921 tctgtttttt cattatgcgt gcgttaggcg aacttctgtt atcaaacacc aataaccatt
    13981 cttttctgga ttttgttgca gaatatcttg gcaaaaaagc ggctttcatc actggctgga
    14041 cgtattggtt ctgctgggta tcgattgcaa tggccgattt aacagccatc ggaatgtatg
    14101 tacgctactg ggcgcctggt gttcctcagt ggcttcctga actgattgca ttaggtcttc
    14161 ttctttgctt gaatatggtg gctgtctcat tgtttggtga gttagagttt tggtttgcat
    14221 tgatcaaagt tgtagcgatc attgccttta tcctcgtagg agcttatatg atcctcaccc
    14281 actatacgac agatattggc acagccagta tcacgaatct atggtctcat ggcggattct
    14341 ttccaactgg tgcaaaagga tttatcttag ctttccaaat ggtaaccttt gcttttgctg
    14401 ggatagaatt agttggatta gtcgctggag aaacagaaaa tcctgaaaaa gtgttgccgg
    14461 aagctatcaa taatattcct atcaggatca tcttatttta cttaggatct ctttttgtca
    14521 ttatggcaat ctatccatgg aacagcttga atccagataa cagtccattt gtagaagtat
    14581 tttcggaaat tgggatcacg attgctgctt ccttgatcaa tttagtcgta ttaagtgcag
    14641 cagcttctgc ctgcaacagt gcaatatata gtacaggacg tatgcttcgt tctttagcgc
    14701 aagaaggcag tgcccctaaa aaattcaaaa agttaacaac acatcatgtg ccagggaatg
    14761 ctttgacatt ttctactatc gtcattttca tttctgttat cttgaattac gtgatgccta
    14821 gtgaagtatt cacactagta agcagtattg ccactacttg tttcttgttt atctggagta
    14881 tgcttgtcta cacgcacatg aaatatcgta aaagtatcct cggcaaaaaa gctcattcat
    14941 ttaaaatgcc gttgtaccca tttagtaatt atctggtatt tctttacatg gcctttgtgt
    15001 gtgtcgtctt gttcctagga aaagatacga gaatcgcttt attactaaca cctgtgtggt
    15061 tcttgcttct attactaatc tatcatatga aatatgaacg taagaagtaa gaaagtagtt
    15121 gtgacagaag tggtcagctt cgagaaataa gaaggaattt acgaaaattg cttcttaaat
    15181 ttttgtgaaa tttcggctta tttcttggag ataaaagctt ctgtcccagc ctcttttcta
    15241 tttccccgga aacaaccgct gataataggc atctgctttt ttataggaaa aaatccaaat
    15301 accagataca aaaaaacgtc cgaataaccc gatcaacggt acaaaaaaga caccggcaat
    15361 caagcataag ttaatcatca tggagataag acttcgacgg tcctttgaca aaactctcac
    15421 gacatgggaa tctggtttat ttgctttcat gatttgcctc atcaagatac caaaagaaaa
    15481 actccacatc gtgtatacta agacataagc catctcaggc caaaaagctt cagggttacg
    15541 cccgacccaa ctagtaacag aaggacataa agtcagccaa aagagcaaaa agatattcga
    15601 ccagaccact cggtaattaa ttcgttctgc catctgaaat atacgatgat ggttcaccca
    15661 gatcaccgca acaaatataa agctgatggt ataagctaat aatgtatttc ggatgaccca
    15721 taaagaatga aagctagatg tattagggat cttgatctct aatacaataa ctctcaaaac
    15781 aatggctacc actccatcag taaatgcttc taatctcgac tttgtcacga tgattcctcc
    15841 tcagatgatt cagcgctttt attttatcac ttacgttatt aaataaccat cgttttatat
    15901 agggaatttt ctgaaaattg ttgcatattt ttcgaaattt tgttactttt aaaaaaaccg
    15961 taaaggagtt atgtatgaca aaaaaattat catttaaaga ctatcttttt ataggctcca
    16021 tgcttttcgg tctatttttt ggtgctggaa atcttatctt tcccgttcat ttgggtcaag
    16081 aagcaggcgc tgctaccttt tgggcgaatc taggtttctt ggttaccggt atcggtcttc
    16141 ccttcttagg ggtgattgcc attggtgtat cgaaaagctc aggtgtatat gaattagcaa
    16201 aacggataaa tcaaacatat gcgatggttt ttaccatctt gctttactta gttatcggac
    16261 cgttttttgc tttacctcgc cttgcaacca catctttcga gattggttta gcaccattta
    16321 tcgatcctag cagacagacg ctatatctag caattttcag tattgtattt tttgtgctgg
    16381 cttggtggtt ttcaagaaaa ccgacaaaga tattagatta tgttggaaag ttcctgaatc
    16441 ctgcattttt ggttttatta ggtgctttgc ttctccttgc ttttttgaat ccactaggtt
    16501 ctgtaaatca agcgcctatt cagccaaatt atcaagagca tgcttttttc acagggttta
    16561 ctcaaggata taacacatta gatgcgcttg ctgctttagc atttgggatc atcattgtca
    16621 caacaatcca aaacatgggt gtaacaaaac ctgctgaaat cgctaaagac acgatcaaat
    16681 ctggtgcgat cagcattata ttgatgggaa tcatttatac tttgctcgct tatttaggtg
    16741 ctatgagctt aggtagcttt gctctaagtg aaaatggcgg gatcacgctg gctcagattg
    16801 ctgatcatta tttaggtact tatggcagta tcttattagc atttatcgtt atattagctt
    16861 gcttgaagac cggtattggt ttgattacag cttttgcaga aacattcaca gatttgtttc
    16921 cgcaaagaaa ttacgcattc tttgttgcac ttgctagtat ccttccttgt ttagcggcaa
    16981 acgtaggctt gacgaatatc attcaatttt cgttgcctgt tttgatgttc atctatccat
    17041 tagcaatgac actgatttta ctagtgttag ttggtccttt gtttaagcag cgtacggctg
    17101 tttatcgaat gactacttat tttacattga ttgcttcgat ttttgatggg ttgaacgctt
    17161 gcccagaaac tatcaaacaa acacctattg ttcaaaatct tttatatgtt gcggaaagct
    17221 acttgccgtt tttcaaattg gggatggggt ggatcgtacc agcagttatc ggttttgtta
    17281 tcggactgat ttggagtttc gctaagaaag aagaagtagc agattgataa aagaggttgt
    17341 gaaagagacg ttcagccttg agcaataaaa agtaattttg aaaaatggct tctcacattt
    17401 ttgcataaat ttgacttaat accgagaaac tgacttttga acaccgttta ttgagaggtc
    17461 gtgaaaaagc cgcttagttt caagtattaa gaaatatttt gtgaaaatgg cttctcacat
    17521 ttttgcataa atttgactta ataccgagaa actggctttt gaacaccgtt tattgagcgt
    17581 ctataaactg acctgagtat tagagaaaca aaacggcaaa gtagctccat atactttgcc
    17641 gttttgtttt gaactaatac cgaagagaag ctgatcaaac aacatttctt ttataatata
    17701 gattttagac atatatatga tataaaaata gttttcgcaa aa
//
LOCUS       DAFBVQ010000053        17107 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.055, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000053 DAFBVQ010000000
VERSION     DAFBVQ010000053.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17107)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17107)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17107
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.055"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            7..1398
                     /locus_tag="LLC22_002073"
     CDS             7..1398
                     /locus_tag="LLC22_002073"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738174.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK5435330.1"
                     /translation="MNKNGEWSAARRIFIILMDVIVYNAAIYSSFLLKFRGEIPLRNL
                     ETFQHSAIIISVIFIALNILLGAYVFYNRMISDIVFVTVIGQVLMTLGIMVVTFAGRW
                     FAFPRLVILLSFVLGTLFLSIYRILVYKLYLRVSRDKKVVIIGLEKDVAPAIQNFGSK
                     KNNKHKVEAVILDNYYANIKNMIKDIDIVYLASHIEETEKIKIYQLVTKNEKKLFLNT
                     TFENLTLINPNIMNFEDESIIETSGFRIQPEYELFKRLFDIIVSLVLLVIASPFMLFT
                     AILVKVTSPGPIIYKQVRITKNQKEFSIYKFRSMTATAEAKSGPVLAKSNDARVTPVG
                     KFIRAVRFDELPQIFNVLKGDMSIVGPRPERPFFVDQFNAENPYYYLRHNVRAGITGY
                     AQVYGKYVSDYNSKLRFDLLYIKKYSLMLDLKILLQTIKILFDKMSSQGLEEDENVIS
                     LAEIAFPNEKIFR"
     gene            1414..2454
                     /locus_tag="LLC22_002074"
     CDS             1414..2454
                     /locus_tag="LLC22_002074"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 2 protein"
                     /protein_id="HBK5435331.1"
                     /translation="MNNPKFSIIVPVYNAEATIGRTIDILKELDYEEYEVVLVNDGST
                     DQTQEIIQELIENDERFELITTTNQGPGLARNEGIRQSKGEYLLFFDADDTPVKTILS
                     DYDHLLEKSPKADLVVSSFVFRTMDEGRIVSEKENLVTECHYLTHEEFIKDMYQLMNE
                     QLMYVVWNKCYRSDILKNNQILFKTYNSCEDRIFNLHYYEYCHQVIMNPKVEYIYEFE
                     GGKGITNQYRPNKFETFKEFYSLANTVTDDINKDGMAALLLKGTTSVIFSIYSTSART
                     SKEKKDEAKQILSDPVIREAKQIAKTDSSAKKITKLLYNMPAPLFLSAVKVGSFVEVK
                     MPGLMAALKRVY"
     gene            2473..3558
                     /locus_tag="LLC22_002075"
     CDS             2473..3558
                     /locus_tag="LLC22_002075"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 1 protein"
                     /protein_id="HBK5435332.1"
                     /translation="MKRILHFQGRMGLGGAESFMMNLYRKIDRTNYQFDFLIYEDYAD
                     VQDYHSEIERLGGRIFVVPNPKKNIFKYLIEVNKLLKKESFSIVHNQVYFGGGINLWL
                     AKKNGIRQRIAHSHATEDGKSQNIVMNVLRKFLTKLLLQNATDYLAVSQEAGESLFQN
                     HPFEIVHNGIDLELYSKNSEAKVNKRKELDISMSTFVVGNIGRLEKQKNQSYLLEIFL
                     EILKMNSDSYLILVGEGSLRNKLKAKAVELDIEKRVKFLGERNDIPELLSVMDVFVMP
                     SLYEGLPMVGLEAQAAKLKLVLADTISKDTKLTNNVDFVSLDETPQEWAKKVIKEPYA
                     NKITQELKSYDVSYTTEQMESIYSRDH"
     gene            3591..4553
                     /locus_tag="LLC22_002076"
     CDS             3591..4553
                     /locus_tag="LLC22_002076"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyl transferase"
                     /protein_id="HBK5435333.1"
                     /translation="MKICYLILAYNDIGNLKRLVNRLNENAVFIIHIDKKTDIEPFIE
                     AFKSYDNVEFLCNKNRVKIYWGGFSIVQAEINLVKRALQNEKYLKYVLLSGADYPIKD
                     NEYIYNYFKKNSSVEFIRGIDLDQIKHKEFYYKHIDVYQKHDYPRINRNNTTAFKIFR
                     AIINRCLRMIKLPPKIRHHKFDLYHGSQWWALSKECLTELIQMYEQNQQDYLNFKIGM
                     FAPDEKFFHTLFFNSSFKNKNVIGGPDLPLELKNIEETTLQTSKLANIHIIDPSMNKW
                     FDERDIDQIKESEKLFVRKVKSDYSDKLLNRIDKEILKVGNIDE"
     gene            4546..5979
                     /locus_tag="LLC22_002077"
     CDS             4546..5979
                     /locus_tag="LLC22_002077"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-antigen ligase family protein"
                     /protein_id="HBK5435334.1"
                     /translation="MNRIVPVLEKSLLSRDAFRVINLIICLLYFMPSTFNVTNIPMKI
                     AFAWGGIIVLYEVFIKKNFFKMRFSWLLIGAMISFILTIIINRENFLIPSIYNFGYLL
                     ITLIVIFPADFSQSEEEKKKKMVYFNNVFIIIIFLAALISIYQFIFLISYHVPTGTPG
                     LLARQGFIEHRLFGVYTSPNVGAMFGYTSIILSLISVLISKITKTIRVFYMMNFIVQI
                     FYITLSSSRGAQVVICSFLVLFLLLFANSKFRKSIREVLPVKIKWMVSILLVLLVYFS
                     FGTNYAKDFLATIPVSIDRKVEVIESNESDKTPLPEKEVILQHSSDNSEISAGRFTIW
                     KAALKVIRPTLLFGYGETDFYGNSDAKFLKKVDLDTTDVNELKRAHGNMHNGFLQVLV
                     SSGIIAFICIYAFYVLNIFSLLKTFFRSKVNYAFLGIVLIFILSIFIDEMVEAHVLFN
                     KRDVISIVFWYYLGSISYLYLKKGELI"
     gene            5976..7046
                     /locus_tag="LLC22_002078"
     CDS             5976..7046
                     /locus_tag="LLC22_002078"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302730.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435335.1"
                     /translation="MKTAFIAWTPLHLINILNVYQNFYRESKGDLFIYSEFENARRYS
                     ERIKELGLFNDVVFVNHRKIGSSFKRKINLLTNHNQFFSDDLSVYDEIFIQGENYFTK
                     ILFSNVYKKNPDVKLNYIEDGLGTYLKKSIFSTSKNVQRVFKILNKNSIFKKKIDDYF
                     VYCPELLLYDVKNIKKIPKIDENSKLMKNIQSIFGIEEVFVGDKCIFFDQPLLSDGYG
                     IDETDIFAKVNSIFSGKKETLIKLHPRARTNRYGEKNILNSSLPFEVLLLENDFSSTL
                     LISPISTISFSPSMMFEKTINSIMLAKLILNEYTALSEDKKETLTNIVLFCEHYNRLS
                     EEKILLPENWAELRKLVEYGII"
     gene            7033..8454
                     /locus_tag="LLC22_002079"
     CDS             7033..8454
                     /locus_tag="LLC22_002079"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177091.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide flippase family protein"
                     /protein_id="HBK5435336.1"
                     /translation="MGLFNTLSKSKLVKSSFWYTIGNFFIKGISFITIPIFVNITTQA
                     EYGLINNFTSFVSIFSILVGLSLNSAINNASFDYKDDINEFMSSVLSLATLSLIVFLL
                     IGNIYFLFSNAFFDMNQLVFNLMLLQSFASFVISYIQSYFTINFNHFKYLILSFISTF
                     LNIAISVALMQTLYFDDKYVGRVVGGTLSFVLIGLVIYLRIMIKGAHFFDKKQWRYAL
                     KISLPLIPHSLANIVLAQFDRIMINSYLGPAAGGIYSYISNIGIILSVIWMSTNNAWV
                     PWFYGEMSKNNEKKVKKVSNYYLVVFTLITMIVMVVSIDLAKFMAPKDYYSGLSLVVP
                     ITLGYFFQFLYSLPVNAEFYEKKTSFIAIGTVASAIVNILLNMIFIPRLGIIAAGYTT
                     VFTYFLLFIFHYNIAKKITNKQLFDTKKICIIIIFVSIFSLILHILINQMLIRYVLTS
                     LLIISLVIYFLKIKNRIIDDYNS"
     gene            8467..9474
                     /locus_tag="LLC22_002080"
     CDS             8467..9474
                     /locus_tag="LLC22_002080"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347627.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polysaccharide biosynthesis protein"
                     /protein_id="HBK5435337.1"
                     /translation="MFKGKTILVTGGTGSIGSEIVRQLLKYEPKAIRIYSRGEEKQFY
                     MQQELSNHTNLRFLIGDIRDSQRIDYACRDVDIIFHAAAMKHVPASEYNPMEAVKTNV
                     MGTQNVIDAAIKNNVKHFVGISTDKVVSPTNTMGATKLLSEKLIIAANQYKGKTETIF
                     SCVRFGNVMGSSGSVIPLFSKQIKNNKDITLTDVDMTRFMMSIPDAARLVLSAAMNSK
                     FGETYVLKMPAINILTLAQSLIKIYNDTHDEKYRGEIKVVGIRPGEKLYEELMTTDEI
                     ERSYENDKMYIIPPHYHATDELYKDYEKIKITAYSSDATELMSGQEFIRIAKENNVVT
                     W"
     gene            9486..10490
                     /gene="neuB"
                     /locus_tag="LLC22_002081"
     CDS             9486..10490
                     /gene="neuB"
                     /locus_tag="LLC22_002081"
                     /EC_number="2.5.1.56"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylneuraminate synthase"
                     /protein_id="HBK5435338.1"
                     /translation="MKSEVYVIAEIGVNHNGSLDLALESIDKAKECGANAVKFQTFKT
                     NKLVSKKAPMAKYQKDNLKEDSSQFEMLKKLELSQSDFIRIKDYCIQNKIDFLSTPFD
                     EESADFLKQIGVQGFKIGSGDLTNLPFLRKIDMYGLPVLLSTGMADIHEVSEAVDCFI
                     DSPVTILHCTSNYPASSEDINLLAINTLKEMFGIPVGYSDHSLGYDVGICAVAMGAKV
                     IEKHFTLDKELPGPDHKASLDPQEFADFVKHIRNTEIFLGDGVKRAMPSELSTKEVSR
                     KSLVVTENLNVGDILTEKSLTIKRPGNGIAPKFLYQYIGKKVKRPISADSVLLEEDVE
                     "
     gene            10487..11635
                     /gene="neuC"
                     /locus_tag="LLC22_002082"
     CDS             10487..11635
                     /gene="neuC"
                     /locus_tag="LLC22_002082"
                     /EC_number="3.2.1.183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177093.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UDP-N-acetylglucosamine 2-epimerase
                     (hydrolyzing)"
                     /protein_id="HBK5435339.1"
                     /translation="MKKILIVSGTRADYGIYKPVAENLLQDNWDVSFVVSGMHLSHKY
                     GFTKELILADGFRISGEVQSLFLENNKGNMARSVALEINGFTNIFEQTSPDFVLLLGD
                     RGEMLAAAIACLYLGIKTAHIHGGEVSGTVDESIRHAITKIASVHFAATEKSKERLIK
                     MGEDSWRVFPVGAPRIDTILNNRLPSFRDIKEKYHLKFEKKKYVLQVFHPVVTELENI
                     EKQILALINSMEQQSQPIICILPNSDAGSEIIRKMYQKYLKTDIIYITNLEPEEYLTI
                     LKECKFMIGNSSSGIIEAASFKIPVINLGTRQNGREQSKNIINANLNENEIETALNKI
                     QDPQFIKSLKNVKNIYGDGNSSRRITKTLNQILNDGEDIKWIQKQIAY"
     gene            11608..12285
                     /locus_tag="LLC22_002083"
     CDS             11608..12285
                     /locus_tag="LLC22_002083"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177094.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetyltransferase"
                     /protein_id="HBK5435340.1"
                     /translation="MDSKTNSLLKYTSDPYIIIGAGGHAKVIIETLRLENKLIYGFFD
                     DKQNKMQDLKYLGKINELNSWADSKKKIYKFIVAIGDCVVRKKIIKKLNMPSEQYGIA
                     VHPSAIVAKEISIGYGTVIFANAVINPDAVIGEHAIINTGSIVEHDCRINNYVHLSPG
                     VCLAGGVHVGVGTQIGIGSQCIQMKKIGSWCMIGAGSTIVKDIPSHSLAYGNPAKIKK
                     EGINFEF"
     gene            12275..13417
                     /locus_tag="LLC22_002084"
     CDS             12275..13417
                     /locus_tag="LLC22_002084"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminotransferase class I/II-fold pyridoxal
                     phosphate-dependent enzyme"
                     /protein_id="HBK5435341.1"
                     /translation="MNSRILLSSPHMGGTEEKYVAKAFKDNWIAPLGENVDKFEESIT
                     KYTGSKGGASALSSGTAAIHLALRLLNVGKNDIVFAPSFTFIATVNPILYQGAVPVFI
                     DSEPNTWNMSPVALESALEEAERNNQLPKAIIVVNLYGQMADYERILAIANQFNVPVI
                     EDAAESLGSTYKGISSGLFGTIGIYSFNGNKIITTSGGGALVSSDKKYVEHSRFLATQ
                     ARDQAPYYQHSEIGYNYRLSNISAGIGRGQMEVLNDRVAKRREIFNRYKEAFSGIDRI
                     EMMPEVDGMVPNRWLSTLTINDYNSIDQVVNVINKLNEKNIETRALWKPLHLQPVFQG
                     VKMYYHDNNLSVSEKLFNSGLCLPSGSNMTDSEQEFVIDEFKKIFK"
     gene            13430..14407
                     /locus_tag="LLC22_002085"
     CDS             13430..14407
                     /locus_tag="LLC22_002085"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342242.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gfo/Idh/MocA family oxidoreductase"
                     /protein_id="HBK5435342.1"
                     /translation="MNIGIIGLGSMGKRRLRLIQEHFNDILLCGVDTNEARRKEVEKE
                     FGIPTYNSLTEAKNLFEINSVFVCTSPITHEFIIKEALNLDCNIFTEINLLNEYYDEI
                     IEVAKKKDRLLYLSSTFLKRKEIQYIKSKVTHNKKISYQYHVGQYLPDWHPWEDYRNF
                     FVSNKKTNGCREIFAIELPWIIDTFGKVKSFTVMTQKLSNLDIDYSDSFTLIIEHETG
                     IVGTLSVDVVSRVAKRNLTIIGEKILIEWEGNPDSLFSWNEETSSMTDIQLYDEVMHD
                     NNYSHTIIEDAYLEEIKEFFTLLEKKMEPQYTFEKDKYIINLINDIEVN"
     gene            14407..15315
                     /locus_tag="LLC22_002086"
     CDS             14407..15315
                     /locus_tag="LLC22_002086"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177096.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dehydrogenase"
                     /protein_id="HBK5435343.1"
                     /translation="MMKVIFFGLGSIGKRHLKNLISYGKKNSINFDITAYSSSGKKEF
                     EEITYIQNRDDLDTHYDIAFITNPTFKHLETLNVIVEKVDYIFLEKPAFSESIDLTQY
                     NYDYKNIYVAAPLRYKNIMEVVRNSIQSKKVYSVRAICSTYLPDWRKGTDYRNNYSAF
                     KSMGGGVELDCIHELDYIINLFGFPKSVKKQFGKYSNLEINSNDLATYILRYDDKIIE
                     IHLDYFGRVPTRKFQLFTLDECINVDLLNNKISFEENIVKEMPESANDMYEKELKYFF
                     ENVVTGKENWNDLYHANEVLKIAEEK"
     gene            15316..16068
                     /locus_tag="LLC22_002087"
     CDS             15316..16068
                     /locus_tag="LLC22_002087"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289370.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylneuraminate cytidylyltransferase family
                     protein"
                     /protein_id="HBK5435344.1"
                     /translation="MEILFTICGRAGSKGFKNKNLKYLAGKPLVHFALAMIDIYQQKH
                     PEHNCTTCLNTDSNELVELTTKLNPSVKIVERKPELATDTVGKIEVIRDSFLQLERED
                     NIFDLIIDLDLTSPLREVSNLEELIDEHLKNLDKDVYFSVVSARRNPYFNMVKRIENE
                     VTIVNKSRYTSRQQTPEVFEMNASMYSFKPEFLKKSNYIFDGQCGIIKMRDYLILDID
                     SEEDFKWLEFLFPKFLEDSSELQDIYNYLYRR"
     gene            16073..17020
                     /locus_tag="LLC22_002088"
     CDS             16073..17020
                     /locus_tag="LLC22_002088"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD-dependent epimerase/dehydratase family
                     protein"
                     /protein_id="HBK5435345.1"
                     /translation="MSCYLITGGAGFIGSTLANHLGEEHVVIVVDDLSMGKVENLDMT
                     KNITFIEGDVAEKSLMEEIMKANKFDYIFHLAAVASVADSVARPVETHRVNFESVLMI
                     LELIRKYQPDLKRIVFSSSAAVYGDEPTLPKKEESVIRPLTPYAVDKFAAEQYVLDYC
                     HLYDVPGSAVRFFNVYGPNQNPNSPYSGVISILVDRYKKQIVGEATSFTLFGDGSQSR
                     DFVYIDDVIQALLLVANEEAALGKQFNVGTGKATTLLELIHAINEILGVELTLEYKEE
                     RSGDIHDSLADITKIQSIGYQPKYGILSGMTNYLKTEIN"
BASE COUNT         6164 a         2190 c         3090 g         5663 t
ORIGIN      
        1 gtatatatga ataaaaatgg agaatggagt gctgcacgac ggatattcat tatattaatg
       61 gatgttattg tatacaatgc agcaatatat agtagtttct tactgaagtt tcgtggagag
      121 atcccattac gaaatttaga aactttccaa cactcagcaa ttattatttc agtgattttt
      181 attgcgttga acattttgtt gggtgcatat gttttttata atcgaatgat cagtgacatc
      241 gtgtttgtca cagtcatcgg tcaggtattg atgacactag ggatcatggt agtgactttt
      301 gcgggccgct ggtttgcttt tccacgtctt gttatcttac tttcatttgt tctcggtacg
      361 cttttcttaa gtatctatcg tattctcgta tataaacttt atttacgcgt aagtcgagat
      421 aaaaaggtcg tcattattgg gttagaaaag gatgtcgcac cagcaatcca aaattttggt
      481 tcaaagaaaa acaacaaaca taaagtcgaa gcagtcattc ttgataacta ttatgcaaac
      541 atcaaaaata tgattaaaga catcgatatt gtctatcttg cttctcatat cgaagaaact
      601 gaaaaaatca aaatctatca attagttact aaaaatgaaa aaaaattgtt tttgaataca
      661 acatttgaaa acttgacatt gatcaatcca aatattatga atttcgaaga tgaaagtatt
      721 attgaaacat ctggatttag aatccaacct gaatatgaac tattcaaacg tttgtttgat
      781 atcatcgttt cacttgtttt attagttatt gcttcaccat ttatgttatt cacagcaatt
      841 ttagtcaaag tgacatcacc gggaccaatc atctataaac aagtgcggat cacaaaaaat
      901 caaaaggaat tttcaatcta taaattccgc tcgatgaccg ccacagccga agcaaaatct
      961 ggaccagttt tagctaagag caatgatgca cgagtaacgc ctgtaggtaa atttattcga
     1021 gctgtccgct ttgatgaatt accacaaatc ttcaatgtgc tgaaaggcga tatgtcgatc
     1081 gtaggaccac gtcctgaacg tcctttcttc gtcgatcagt tcaatgcaga aaacccttat
     1141 tactacttac ggcataatgt tcgtgctggt atcactgggt atgcacaagt ctatggaaaa
     1201 tatgtctctg attacaacag taaattacgt tttgatttac tttatatcaa aaaatattca
     1261 ttgatgcttg atttaaagat cttgctgcaa accatcaaga tcctatttga taaaatgtcc
     1321 tctcaaggac ttgaagaaga cgaaaatgtg atctcattgg cagaaattgc ttttccgaat
     1381 gaaaaaatct ttcgctagtt gggaggcgta aaaatgaaca atccgaaatt cagcataatc
     1441 gtaccagtat acaatgcaga agcaactatt ggtcgaacga ttgatattct aaaagaattg
     1501 gattatgaag agtacgaagt cgttttagta aatgatggat caacagatca aacacaggaa
     1561 atcattcaag aactgattga aaatgatgaa cgttttgaat tgattactac gaccaatcaa
     1621 gggcccggat tagcaagaaa cgaaggaata agacagtcaa aaggagaata tctcttattc
     1681 ttcgatgcag atgacacgcc agtaaaaacg atcttgtcag attatgatca tttgctagaa
     1741 aagagtccaa aagcggatct tgttgttagt tcgtttgttt ttcgtacaat ggacgaggga
     1801 agaatcgttt ccgaaaaaga aaacttagtt acagaatgtc actatctaac tcacgaagag
     1861 tttataaaag acatgtatca gttaatgaat gaacagttga tgtatgttgt atggaacaaa
     1921 tgctatcgta gcgatattct gaaaaataac caaattctat ttaaaactta taatagttgt
     1981 gaggatcgaa tatttaactt acattattat gaatactgtc atcaagtgat catgaaccca
     2041 aaagtagaat atatttatga atttgaaggt gggaagggga tcactaatca ataccgacct
     2101 aacaagttcg aaacatttaa agaattctat tcattagcaa atactgtaac agacgatatt
     2161 aataaagacg gtatggcggc gcttctttta aaagggacaa cttcagttat tttttctatt
     2221 tatagtacct ctgcaagaac ttcaaaagag aagaaagacg aagcaaagca gatattgagt
     2281 gatccagtga tccgagaagc caagcaaatt gctaagacgg attcttcagc aaaaaaaata
     2341 acaaagttgc tttacaatat gccagctcca ctatttttat ctgctgtaaa agttggaagc
     2401 ttcgttgaag tgaaaatgcc agggttaatg gctgctttga agcgagtata ttagttaatg
     2461 gaggaaaata taatgaaaag aattttgcat tttcagggac gaatgggttt aggtggagca
     2521 gagtctttca tgatgaattt atatcgtaaa attgatcgta caaactatca atttgatttt
     2581 ttgatttatg aagattatgc agatgttcaa gactatcatt cagagattga aagattagga
     2641 ggccgtattt ttgttgtacc taatcctaag aaaaatattt ttaaatattt aatagaagtg
     2701 aataagttac taaaaaaaga atctttttct atagttcaca atcaggttta ttttggcggg
     2761 ggaattaatt tatggttagc caaaaagaat ggaatcagac agagaattgc tcatagccat
     2821 gcaactgaag atggaaaatc tcaaaatatt gtaatgaatg tattgcgtaa atttttaacc
     2881 aaattgttgt tacaaaatgc aacagactac cttgccgtta gtcaagaagc tggtgaaagt
     2941 ctgtttcaaa accatccctt tgagatagtt cataatggta ttgatttaga gctttatagt
     3001 aaaaattcag aagctaaggt taataagaga aaagaattgg atatctcaat gagtactttt
     3061 gttgtgggaa acattggacg attagagaaa caaaaaaatc aatcttattt gttagagatt
     3121 tttttagaaa tactaaaaat gaattctgat tcttacttga ttttagtagg tgaagggtca
     3181 cttagaaata aactgaaagc caaagcagta gaattggata tagagaaaag agtaaaattt
     3241 ttaggagaaa gaaacgatat tcccgagtta ttatctgtga tggatgtttt tgtaatgcct
     3301 tctctttatg aaggtctgcc aatggttgga ttagaagcac aagcagcaaa attaaaatta
     3361 gtcttagcag atactatttc caaagataca aagttaacaa ataatgtgga ttttgtatca
     3421 ttagatgaaa caccacaaga atgggcaaaa aaagtaataa aagagccgta tgctaataaa
     3481 ataacacaag aactaaagag ttatgatgtt tcgtacacta ctgaacaaat ggagagtata
     3541 tatagtagag atcattaaaa atgttcaaga tattttagga gtgattattt ttgaaaatat
     3601 gttatttgat attggcatac aatgatattg gcaacttaaa gagattggtc aatcgattga
     3661 acgaaaatgc agtttttatt attcatatag ataaaaaaac tgatatagaa ccatttattg
     3721 aagcatttaa atcatatgat aatgttgaat ttttatgtaa taaaaaccgt gttaaaattt
     3781 attggggtgg tttttccatt gtacaagcag aaatcaattt agtaaagaga gcattacaaa
     3841 atgagaaata tttaaaatat gtattattat ctggtgctga ttatccaatc aaagataatg
     3901 agtatattta taattatttt aaaaagaata gttcagtgga gtttattcgt ggaatagatc
     3961 tagatcaaat taaacataaa gaattttatt ataaacatat agatgtatat caaaaacatg
     4021 attatcctag aattaatagg aataacacaa ctgcatttaa aatttttaga gctataatta
     4081 atcgttgtct gaggatgatt aaacttcccc caaaaattag acaccataaa tttgatttgt
     4141 atcatggttc tcaatggtgg gctttgtcga aagaatgcct aacagaatta atacaaatgt
     4201 atgaacaaaa tcaacaagac tacctgaatt ttaaaatagg tatgtttgcc ccagatgaaa
     4261 aattttttca tacacttttt tttaattcct cgttcaaaaa taaaaatgtt attggaggac
     4321 cagatttacc acttgaattg aaaaatattg aagaaactac tttacaaact tcgaaattag
     4381 caaatattca tattattgat ccttccatga acaaatggtt tgatgaaagg gatatagatc
     4441 aaataaaaga aagtgaaaaa ttatttgtaa gaaaagttaa atcggattac tctgataaac
     4501 tattaaatag aattgataaa gaaattttga aagttggaaa tatagatgaa tagaatagta
     4561 cctgttttag agaagagttt attaagtcga gatgcgtttc gagtaataaa tttaatcatt
     4621 tgtctgcttt attttatgcc tagtactttt aatgtaacta atatcccgat gaaaatagct
     4681 tttgcttggg gtggaattat agttttgtat gaggttttta taaagaaaaa tttttttaaa
     4741 atgcgttttt cttggctact gattggagca atgattagtt ttatcttaac tataatcatt
     4801 aacagagaaa attttttaat tccatctatt tataattttg gatatttgct gattactttg
     4861 atagtaattt ttcctgcaga cttttcacaa agtgaagagg aaaaaaagaa aaaaatggtg
     4921 tattttaata atgttttcat tatcataatt tttttagctg cgctaatatc tatctatcaa
     4981 tttatttttt tgatttctta tcatgtccca acaggaacgc caggattact tgcaagacaa
     5041 ggttttattg aacatcggtt atttggtgtc tatacaagtc caaatgttgg agctatgttt
     5101 ggatatactt ctattatttt aagtttaatt agtgtattaa tttcaaaaat aacaaaaacg
     5161 attcgtgttt tttatatgat gaattttatc gtacaaatat tttatattac actttcttcg
     5221 tctagaggtg cccaggtagt aatttgttct tttttagtat tatttctttt gttgtttgcc
     5281 aattcaaaat ttagaaagag cattagagaa gtactacctg taaaaatcaa atggatggta
     5341 agcatattat tagttctatt ggtatatttt tcttttggta ctaattatgc taaggatttt
     5401 ttagcaacaa ttcctgtatc gattgataga aaagtagaag ttatagagtc aaatgaatca
     5461 gataaaactc cacttccaga aaaagaagta atattacagc attctagtga taactccgaa
     5521 atttcagctg gtcgttttac gatttggaaa gctgcgctta aagttataag accaactttg
     5581 ttatttggtt atggagagac cgatttctat gggaatagcg atgcaaaatt tttgaaaaaa
     5641 gtagatcttg atactacaga tgtgaatgaa ctaaaaagag cacatggaaa catgcataat
     5701 ggatttcttc aagtacttgt atcaagtggt ataattgctt ttatatgtat ctatgctttc
     5761 tatgtgttaa atatctttag tttactcaaa acatttttta gaagtaaagt gaattatgcg
     5821 tttcttggta ttgttttaat ttttatacta tctattttta tagatgaaat ggtggaggct
     5881 catgtacttt tcaataagcg cgatgtcatt tcaattgttt tctggtatta tttgggaagc
     5941 atttcttact tgtatttaaa aaaaggagaa ttaatatgaa gacagctttc attgcttgga
     6001 ctcctttaca tttgattaat atattaaatg tttatcaaaa tttttaccga gaatcaaaag
     6061 gagatttatt tatttattct gaatttgaaa acgctagaag atatagtgag cgtataaaag
     6121 aattagggct atttaatgat gttgtttttg tgaatcaccg gaaaatcggt tcttccttta
     6181 aacgtaaaat taacttgtta actaaccata atcaattttt ctcggatgat ttatccgttt
     6241 atgatgaaat ttttatacag ggggaaaatt atttcacaaa aatacttttc tccaatgttt
     6301 acaaaaaaaa tccagatgta aaactaaatt atatagaaga tggtttgggt acttatttga
     6361 agaagagtat attttcaaca agtaaaaacg ttcaaagagt ttttaaaata ttaaataaaa
     6421 atagcatctt caaaaaaaaa attgacgatt attttgtcta ttgtccggaa ttgttacttt
     6481 atgatgtaaa aaatataaaa aaaattccca aaatagatga aaacagtaaa ttgatgaaaa
     6541 acatacaatc aatctttggg atagaagaag tttttgtcgg agataaatgt atcttttttg
     6601 atcaaccttt attatctgat ggttatggca tagatgaaac agatattttc gctaaagtaa
     6661 atagtatatt ttctggaaaa aaagaaactt taattaagct tcatcctaga gcaaggacaa
     6721 atcgttatgg tgaaaaaaac atattgaatt ccagtttacc gtttgaagtc ttgctacttg
     6781 aaaatgactt ctcttcaaca cttttgatta gtcctatatc tacaatttct ttttcaccat
     6841 ctatgatgtt tgaaaagacg atcaactcta ttatgttggc taaattaatt ttaaatgaat
     6901 atacagcatt atctgaagat aaaaaagaaa cattgacaaa tattgttctt ttctgtgaac
     6961 attataaccg tctatcagaa gaaaaaattt tactcccaga aaactgggca gaattaagaa
     7021 agttggtaga gtatgggatt atttaacaca ctttccaagt caaaattagt taagtccagt
     7081 ttctggtata ctatagggaa tttttttatt aagggaattt cattcataac tattcctatt
     7141 tttgtaaata ttactactca agcagaatat ggtttgatta ataatttcac ttcatttgta
     7201 tcaatttttt cgattcttgt tgggctaagc ctaaattcgg caattaataa tgcaagtttt
     7261 gactataaag atgacataaa tgaatttatg tcatcggtac tttctctagc tacactttcg
     7321 ttaattgtgt tcttattaat agggaacata tattttttgt tttcaaatgc tttttttgat
     7381 atgaaccaac ttgtatttaa tttgatgtta ttacaaagtt ttgctagttt tgtaattagt
     7441 tatatccagt cttattttac gattaacttt aaccatttta aatatttgat tttatctttt
     7501 atatctactt ttttgaatat tgcaatctct gtagctttga tgcagacatt atattttgat
     7561 gataaatatg ttggcagagt agtcggcgga acactgtcat ttgtgttgat aggtttagta
     7621 atttatttaa gaataatgat aaagggtgct catttttttg ataaaaaaca gtggagatac
     7681 gctttaaaaa tctctttgcc gctaatccca cattccttag caaatatagt tttagcacaa
     7741 ttcgatagaa ttatgattaa ttcttattta ggtcctgctg cggggggaat atattcctac
     7801 attagtaaca taggtattat tctaagcgta atatggatgt ctactaataa cgcctgggtt
     7861 ccatggttct atggtgagat gagtaaaaat aatgaaaaaa aagtgaagaa agttagtaac
     7921 tattatttag tagtctttac tttgattacg atgattgtaa tggtagtttc gattgattta
     7981 gcaaaattta tggctccgaa agactattat tctgggttat ctttagtggt tccgataacc
     8041 ttaggctatt tctttcagtt tttatatagt ttaccagtta atgctgaatt ttatgagaaa
     8101 aaaacatcgt ttattgcgat tggtacagta gcaagtgcta tagttaatat actattaaac
     8161 atgattttca tacctaggtt aggaataatt gctgctggat acacaaccgt atttacgtat
     8221 tttttacttt ttatttttca ttataatatc gctaaaaaaa ttacgaataa acaattattt
     8281 gacacaaaaa aaatatgtat cataataatt tttgtatcaa ttttttcttt gatacttcat
     8341 attttaatca atcaaatgtt gattcgttac gttttgacat cattattgat aattagttta
     8401 gttatatatt ttttaaagat taagaatcga attatagatg actataattc ataggaggag
     8461 atataagtgt ttaaaggaaa aacaatatta gtaactggcg gaactggttc cattggaagt
     8521 gaaattgttc gtcagctttt aaaatatgaa ccaaaagcta tcagaattta tagtagaggt
     8581 gaagaaaaac aattttatat gcaacaagag ctctcaaatc acactaattt gagattttta
     8641 attggtgata tcagagactc tcaaaggatt gattatgcat gtcgtgatgt ggatattatt
     8701 tttcatgctg ccgcaatgaa acacgttcca gcaagtgaat ataatcctat ggaagctgta
     8761 aaaacaaatg tgatgggaac tcaaaatgta atagatgcag cgatcaaaaa taatgtaaaa
     8821 cattttgtag gtatcagtac agataaagta gtgagtccta ctaacaccat gggtgcgaca
     8881 aagttattga gtgaaaaatt aataatagct gccaatcagt ataaaggaaa aacagaaaca
     8941 atattttctt gtgtaaggtt tggaaatgtc atggggtcaa gtggatctgt tattcctctt
     9001 tttagtaaac aaataaaaaa caataaagat attactttga cagatgttga tatgacacga
     9061 tttatgatgt caataccgga tgctgcaaga ttagttctgt ctgctgctat gaattcaaaa
     9121 tttggagaaa catatgtctt aaaaatgccg gcaatcaata ttttaacttt agctcaatca
     9181 ttaataaaaa tatataatga tacacatgat gaaaaatata gaggtgaaat aaaagttgta
     9241 ggtatcaggc caggagaaaa attatatgaa gagctaatga ctacagacga aattgaacgc
     9301 tcatatgaaa atgataaaat gtatatcatt ccaccacact atcatgctac tgacgaactg
     9361 tacaaagatt atgaaaaaat taaaatcact gcatactctt cagatgcaac agaattaatg
     9421 agtggacagg aatttattag aatcgcaaaa gagaataatg tcgtgacttg gtaaggagtt
     9481 ttatgatgaa atcagaagta tatgtaattg cagaaattgg tgtaaaccat aatggaagtc
     9541 tagatttagc tttagaaagt attgataaag ctaaagaatg tggagctaac gcggttaaat
     9601 ttcaaacatt taaaacgaat aagctagttt ccaaaaaggc tccaatggca aaatatcaga
     9661 aggataatct taaagaggac agttctcaat ttgaaatgct aaaaaaatta gaattatctc
     9721 aatctgattt tattagaata aaagattatt gtatacaaaa taaaattgat tttttgtcta
     9781 ctccttttga tgaagaaagt gcagactttc taaaacaaat tggtgtacaa ggatttaaaa
     9841 ttggctcagg agatttaaca aatttacctt ttcttagaaa aatagatatg tatgggttgc
     9901 cagttttatt atctacaggt atggctgata ttcatgaggt cagtgaggct gtagattgtt
     9961 tcatagatag tccagttact attttacatt gtacttcaaa ttatccggct agttctgaag
    10021 atattaattt attggcgatt aacacattaa aagaaatgtt cgggataccc gttgggtact
    10081 ccgatcattc attgggatat gatgttggta tttgtgctgt tgcgatgggt gctaaggtaa
    10141 ttgagaaaca ttttaccttg gataaggaac tacctggtcc agatcataaa gcttctttag
    10201 atcctcagga atttgcagat tttgtaaagc atattagaaa cactgaaata tttttaggtg
    10261 atggtgttaa gcgagcaatg ccttctgaac ttagtacaaa agaagtatca agaaaaagcc
    10321 tagtggtcac tgagaattta aatgtgggag atattcttac agagaaatct cttacaataa
    10381 aacgtcctgg aaatggaata gctcctaagt ttttatatca atatattggc aaaaaagtta
    10441 aaagaccaat aagtgcagat agtgttctgc ttgaggaaga tgttgaatga aaaaaatact
    10501 tatagtaagt ggaacacgag ctgattatgg aatatataaa cctgttgctg agaatttact
    10561 acaagataat tgggatgtat catttgttgt ttctggaatg catttatccc ataaatatgg
    10621 atttactaaa gaattgatct tagctgacgg atttagaatt agtggagaag ttcaaagttt
    10681 gtttttagag aacaataagg gaaacatggc tcggtctgtg gcattagaga taaatggttt
    10741 cacaaatata tttgaacaaa ctagccctga ttttgtatta ttactagggg atagaggaga
    10801 aatgttggca gctgcgatag cttgtttgta tcttggaatc aaaacagcac atattcacgg
    10861 aggcgaagtg tctggtactg tagatgaatc aataagacat gccataacga aaatagcatc
    10921 tgttcatttt gctgctacgg aaaaaagcaa agagcgttta ataaaaatgg gggaagattc
    10981 ttggagagtt tttcccgtcg gagctcctag aatagatact attttaaata atagattacc
    11041 tagttttaga gatataaaag aaaaatatca tctaaaattt gaaaagaaaa aatacgtttt
    11101 gcaagtattt catccagttg taaccgaact agaaaatata gaaaaacaaa ttttagcttt
    11161 gatcaattca atggaacaac aatctcaacc aattatttgc attttaccta atagtgatgc
    11221 tggtagcgaa attatcagaa aaatgtacca gaaatattta aaaacggata ttatttatat
    11281 tacgaattta gagccggagg aatacctgac tatattaaaa gagtgcaaat ttatgatcgg
    11341 aaattcttct tctgggataa ttgaagctgc atcattcaaa ataccagtaa taaatttagg
    11401 aaccagacaa aatggacgag aacaatctaa aaatattata aatgcaaatc taaatgaaaa
    11461 tgaaattgaa actgctttga ataaaataca agatcctcag tttataaaaa gcttgaaaaa
    11521 tgttaagaac atctacggtg acggcaacag ttctagaaga ataacaaaaa cattgaatca
    11581 aatattgaat gatggggaag atattaagtg gattcaaaaa caaatagctt attaaaatat
    11641 actagtgatc catacattat tattggggct ggcggacacg caaaagtcat tattgaaacc
    11701 ttaagattag aaaataagtt aatatatgga ttttttgatg ataagcaaaa taaaatgcaa
    11761 gatctgaaat atcttgggaa aataaacgaa ttgaatagct gggcggatag caaaaaaaaa
    11821 atctataaat ttattgtagc tattggtgac tgtgtagtaa gaaaaaagat tataaaaaaa
    11881 ttgaatatgc caagtgagca atatggaata gctgttcatc caagtgctat agtggcaaaa
    11941 gaaatttcaa ttggttatgg aactgttatt tttgcgaatg ctgtaattaa cccagatgct
    12001 gtaattggag agcatgctat aataaacaca ggtagcattg ttgagcatga ttgtagaatt
    12061 aataactatg ttcatttatc tccaggtgta tgcttagcgg gtggagtaca tgtaggtgta
    12121 ggaactcaaa taggaattgg ttctcaatgt atccagatga agaaaattgg atcttggtgt
    12181 atgataggcg cagggagcac tattgttaag gatattccct cacattcctt agcttatggc
    12241 aatccagcta aaattaagaa agaaggaatt aattttgaat tctagaattt tattatcaag
    12301 tcctcatatg ggaggaacag aagaaaaata tgttgctaag gcttttaaag ataattggat
    12361 agcgccatta ggtgaaaatg tggataaatt tgaagaaagt attacaaaat atactggttc
    12421 taagggcgga gcttctgcgt taagttcagg tacagctgcc atacatcttg ccttaagact
    12481 gcttaatgtt ggaaaaaacg atattgtctt tgctccttca tttactttta tagctacagt
    12541 aaatcctatt ttatatcaag gggctgtacc agtgttcatt gactcagaac ctaatacatg
    12601 gaatatgagc cctgttgcac tagagagcgc attagaagaa gctgaaagaa acaaccaatt
    12661 acctaaggca atcatcgtag tgaatttata tggtcaaatg gctgattatg aacgaatttt
    12721 agctattgca aaccaattta atgttccagt gatagaagat gcagcggaat cgttaggttc
    12781 tacttataag ggaatttcgt caggcttatt tgggacaatt gggatctatt catttaacgg
    12841 taataagatc atcacaacct caggtggagg agctctagtg tctagtgata aaaaatatgt
    12901 tgagcattca agatttttag caacacaagc aagagatcaa gcaccgtatt atcaacatag
    12961 cgaaataggt tataattacc gtctaagcaa tatttctgcc ggtatcggac gtggacaaat
    13021 ggaagtattg aatgatagag tagctaaacg aagagaaatt ttcaatcgat ataaggaagc
    13081 tttttctgga attgatagaa ttgaaatgat gccagaagtg gatggcatgg tgccaaatcg
    13141 ttggttgtct actttaacga tcaatgatta taattctatt gatcaagtag ttaacgtaat
    13201 aaataaacta aatgaaaaaa acattgaaac aagagctttg tggaaaccac tacatttgca
    13261 accagtattt caaggggtaa aaatgtatta ccatgataat aatcttagtg tgtcagaaaa
    13321 gttatttaat agcggcttat gcttaccttc tggaagtaat atgacagata gtgaacaaga
    13381 atttgttatt gatgagttta aaaaaatatt caagtaggtg tgatatttta tgaacatagg
    13441 aattattggt ttaggttcca tggggaaaag aagacttaga ctcattcaag aacactttaa
    13501 tgatatttta ctatgtggtg ttgatactaa tgaggcgaga cgaaaggaag ttgaaaagga
    13561 atttggaata ccaacttata atagtctaac agaggcaaaa aatttgtttg aaataaattc
    13621 agtttttgtt tgtacatccc ctataaccca tgaatttatt ataaaagagg ctttaaattt
    13681 agattgtaat atctttacgg aaatcaattt attaaatgaa tattatgatg aaataatcga
    13741 agtagctaaa aagaaagata gattacttta tctatcttct acatttttga agagaaaaga
    13801 aattcaatat attaagtcta aagtgacgca taataaaaaa atttcttatc aataccatgt
    13861 aggacagtat ttacccgact ggcatccttg ggaagattat cgcaattttt ttgtttcaaa
    13921 caaaaaaact aatgggtgta gagaaatatt cgctattgaa ttaccttgga ttatagatac
    13981 atttgggaaa gttaaatcgt ttactgtaat gacccagaaa ttatccaatc ttgatattga
    14041 ttattcggac agtttcactc ttattattga gcatgaaact ggtatagttg gaactttaag
    14101 tgtagatgtt gtttcaagag tagctaaaag aaatttaact ataattggtg aaaagatttt
    14161 aatagaatgg gaaggtaacc cggattctct attttcatgg aatgaagaaa cttctagtat
    14221 gacagatatt caattgtacg atgaggttat gcatgataat aattattcac atactattat
    14281 tgaagatgca tatttagagg agattaaaga atttttcacg cttttggaaa agaaaatgga
    14341 accccaatat acttttgaaa aagataagta tattattaac ttaattaacg acattgaggt
    14401 aaattaatga tgaaagtaat tttttttggg ttagggtcaa ttggaaagag acatctaaaa
    14461 aatctaataa gctatggaaa aaagaattct attaattttg atataacagc ttatagtagc
    14521 agtggaaaaa aagagtttga agaaataacg tatattcaaa atagagacga tttggataca
    14581 cattatgata tagcttttat tacaaatccg acttttaagc atctggaaac actaaatgta
    14641 attgttgaaa aagttgatta catattttta gaaaaacctg ctttttctga gagtattgat
    14701 cttactcaat ataattatga ttacaaaaat atttatgttg ctgctccact gaggtataaa
    14761 aatatcatgg aagttgttcg taatagtatt caaagtaaaa aagtatattc tgtaagagct
    14821 atttgttcta cttatcttcc tgattggaga aaaggtactg attatagaaa taattattct
    14881 gcctttaaat ctatgggggg aggagtagaa ttagactgta tacatgaatt ggattatatt
    14941 ataaacctat ttggtttccc taaatcagta aaaaaacagt ttggtaaata ttcgaatctt
    15001 gaaattaaca gtaatgattt agcaacatat atattgagat acgatgataa aattatagaa
    15061 attcatttag attattttgg aagagttcct acaagaaaat ttcaattgtt tactttagat
    15121 gaatgtatca atgttgactt attaaataat aaaataagtt ttgaagaaaa cattgttaaa
    15181 gaaatgcctg aatctgctaa tgatatgtat gagaaggagt tgaaatattt ctttgaaaac
    15241 gtagtaacag gcaaagaaaa ctggaatgat ttatatcatg caaacgaagt attgaaaata
    15301 gctgaggaga aataaatgga aattttattt actatttgtg gtagagctgg gtctaagggg
    15361 tttaaaaata aaaatttgaa atatttggca ggaaagcccc tagtccattt cgctttagca
    15421 atgatagata tctatcaaca aaaacatcct gaacataatt gcacgacttg tttgaatacg
    15481 gacagtaatg agttagtaga attgacgact aagttaaatc cgtctgtgaa aattgtagaa
    15541 cgtaaacctg aattagctac agatactgta gggaaaattg aagtgatacg tgattcattc
    15601 ttacaactag aaagagaaga taatatattt gatttaatta tagatttaga tttgacttca
    15661 cctttacgtg aagtttctaa tcttgaagaa ttaatagatg aacatctaaa aaatttagat
    15721 aaagacgtct acttttcagt tgtttctgca agacgtaatc cctattttaa tatggtaaaa
    15781 agaattgaaa atgaagttac tatagttaat aaatcaagat acacatctag gcaacagaca
    15841 cctgaagttt ttgaaatgaa tgcctcaatg tattctttta aacctgaatt tctaaaaaaa
    15901 agtaattata tttttgatgg gcaatgtggg ataataaaaa tgagagatta tctaatttta
    15961 gatattgata gtgaagaaga ttttaaatgg ttagaatttt tgtttcctaa atttttagaa
    16021 gattcttcgg agcttcaaga tatctataat tatttatatc ggaggtaaaa ggatgagctg
    16081 ttatcttatc accggtgggg ctggcttcat tggttctacc ttagccaatc atttaggaga
    16141 agaacatgtg gtaatcgtcg tcgatgactt atcaatggga aaagtagaaa atcttgatat
    16201 gacgaaaaat atcactttta ttgagggaga tgtcgctgag aaatccttga tggaagagat
    16261 catgaaagct aataaatttg attatatctt tcatttagca gcagttgcta gtgtggcaga
    16321 ttcagttgcc cgaccagtag aaacacatcg tgtgaatttt gaaagtgtat taatgatttt
    16381 agaattgatc cgcaagtatc aacctgattt aaaacggatc gtgtttagtt cttcagcggc
    16441 tgtttatggg gatgaaccga ctttaccaaa aaaagaagag tccgtgattc gcccattgac
    16501 gccttatgcg gttgataaat tcgctgcaga acaatatgtg ctagattatt gtcatttata
    16561 tgatgtaccc ggtagcgcag ttcgtttttt caatgtctat ggtccaaatc aaaatccgaa
    16621 ttctccatac agtggtgtga tttctattct cgtagatcgc tataagaaac aaatcgtagg
    16681 agaagcaact tcatttacat tatttggtga tggaagccag tctagagact ttgtttatat
    16741 agatgatgta atccaagcat tacttttagt tgcgaatgag gaagctgcac tggggaaaca
    16801 attcaatgtt ggaacgggta aagcaaccac acttttggaa ttgattcatg caatcaatga
    16861 aattctcggt gtagaattga cacttgaata caaagaagag cgttcgggtg atatccatga
    16921 ctctctagca gatattacta agatccagtc aattggctat caaccgaaat atggtatttt
    16981 aagtggaatg actaattatt tgaaaactga aatcaattaa aacatactaa gataagatta
    17041 gagggtaaat tcaggctctt tgtcaataag gactgatgag ttttgtaaaa tcaaatctgg
    17101 gatagaa
//
LOCUS       DAFBVQ010000054        17005 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.056, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000054 DAFBVQ010000000
VERSION     DAFBVQ010000054.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 17005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 17005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..17005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.056"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..124)
                     /locus_tag="LLC22_002089"
     CDS             complement(<1..124)
                     /locus_tag="LLC22_002089"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="EntF family bacteriocin induction factor"
                     /protein_id="HBK5435346.1"
                     /translation="MEEKNRLNAKQCSDQELKKIKGGAGTKPQGKPASNLVECVF"
     gene            complement(228..539)
                     /locus_tag="LLC22_002090"
     CDS             complement(228..539)
                     /locus_tag="LLC22_002090"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBK5435347.1"
                     /translation="MKKNAKQIVHELYNDISISKDPKYSDILEVLQKVYLKLEKQKYE
                     LDPSPLINRLVNYLYFTAYTNKIRFTEYQEELIRNLSEIGRTAGINGLYRADYGDKSQ
                     F"
     gene            complement(541..738)
                     /locus_tag="LLC22_002091"
     CDS             complement(541..738)
                     /locus_tag="LLC22_002091"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class II bacteriocin"
                     /protein_id="HBK5435348.1"
                     /translation="MKHLKILSIKETQLIYGGTTHSGKYYGNGVYCTKNKCTVDWAKA
                     TTCIAGMSIGGFLGGAIPGKC"
     gene            complement(1132..2859)
                     /locus_tag="LLC22_002092"
     CDS             complement(1132..2859)
                     /locus_tag="LLC22_002092"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease/substrate binding
                     protein"
                     /protein_id="HBK5435349.1"
                     /translation="MNNLLNYQLPVANWVENITEWFTTTFSGLFSFLQTIGQAVMSGI
                     TNLLLVIPAPLFILLLTVAAFFISKKRPGLTLFTLIGLWFIYNQGLWNDLMNTVTLVL
                     LSSVISIIIGVPLGILMAKSSKAQSIIKPILDFMQTMPGFVYLIPAVAFFGIGMVPGV
                     FASVIFALPPTVRFTNLGIRQVPKELVEASDSFGSTSRQKLFKLELPLAKSTIMAGIN
                     QTTMLSLSMVVIASMIGAPGLGRGVLSALQRAQVGNGFVNGVALVILAIIIDRFTQHL
                     NQPNNKKAAGATTQKSKKRQGLIIGAVVVVILGAIGIGSFSSAKETKRINLSYVEWDT
                     EVASTNVVGEVLKQMGYDVTMTPLDNSIMWKSVSNGESDAMVSAWLPKTHGSQYAQYK
                     DQVEDLGANLTGAKVGLAVPAYMDVNSIDELTDQAGKKIIGIEPGAGVVTAAENTIQK
                     YDNLKDWKVETSSSGAMTVALGQAIKKHEPIVVTGWTPHWMFAKYDLKYLEDPENGMG
                     SEEQIHTMVRKGLKEDQPEAYKVLDNFHWSEKDMEKVMLEINNGKDPQQAAKDWIKEN
                     QELVESWKK"
     gene            complement(2852..4045)
                     /locus_tag="LLC22_002093"
     CDS             complement(2852..4045)
                     /locus_tag="LLC22_002093"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734321.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine betaine/L-proline ABC transporter
                     ATP-binding protein"
                     /protein_id="HBK5435350.1"
                     /translation="MVKVEVKHLTKIFGKKTQAALDMMNDHQPKTEILKKTGATVGVY
                     DVNFDVKEGEIFVIMGLSGSGKSTLIRLLNRLIEPTSGSIYIDGEDVSKLSKEELREV
                     RRHKINMVFQNFGLFPHRTILENTEYGLEVRGVPKEERQEKAEKALENSSLLSFKDQY
                     PSQLSGGMQQRVGLARALANDPEILLMDEAFSALDPLIRREMQDELLDLQANVQKTII
                     FITHDLNEALRIGDRIALMKDGEIMQIGTGEEILTNPANDYVREFVEEVDRSKVLTAQ
                     NIMVPALTTNIESDGPNVALTRMRNEEVSMLMAVDRKRHLKGIITADQALEARKQKRP
                     LIDFLDENVTVIGKDMVVSDIFNIIYDSPTPLAVVEDGKLKGVVIRGSVIEALAETSE
                     VSEHE"
     gene            complement(4232..4876)
                     /locus_tag="LLC22_002094"
     CDS             complement(4232..4876)
                     /locus_tag="LLC22_002094"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319010.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5435351.1"
                     /translation="MSGKKKIVRPRYQQIAVDLAERIVENRYKVGEKIHARSTLASTY
                     NASPETTRKAINVLVDLGIMEVRHGSGAFVASKEKAKDFLLQYQDVQSIQDTKAEIMA
                     SVEKQQDELNHFSQLLDQLVNQTKRIHKMNPLLPFELSLSEKAMHLDRSISELNIWQA
                     TGATVIAISHNEELLVSPGPYAKFTAGDIVHFIGNEYTLQRMTNFFYPEHQLAE"
     gene            complement(4970..5104)
                     /locus_tag="LLC22_002095"
     CDS             complement(4970..5104)
                     /locus_tag="LLC22_002095"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FeoB-associated Cys-rich membrane protein"
                     /protein_id="HBK5435352.1"
                     /translation="MATFLLSVLIFGSAGAIVYTRLKSGKNCDDCQTACPVKKEQIKR
                     "
     gene            complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LLC22_002096"
     CDS             complement(5106..7238)
                     /gene="feoB"
                     /locus_tag="LLC22_002096"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein B"
                     /protein_id="HBK5435353.1"
                     /translation="MNIALVGNPNSGKTSLFNLLTGSNQYVGNWPGVTVEKKEGSLKK
                     NPNIHIQDLPGIYSLSPYTPEEVIARDYLVQEQPELIINIIDATNLERNLYLTTQLLD
                     LDIPMIIGLNMMDVIKKEGKKINLEKLSYGLGVPVLPISVLKKQGIEKLIEKIQESAK
                     KRPSIPVPCTYDPRLEAALHEIEDVLGEQSGKKRWYAMKYFERDQKVREDYEIAVSQQ
                     KEIEQLIQLTEKLLDDDSETILVNERYEFITQLCTLCVVSNDSFQLSMSDKIDQIATN
                     RWLALPIFAFVMWLIYYLAIQTVGTMGTDWINDTLFGTWLPEHVGRLLAEWQVAGWMQ
                     ELILNGIIAGVGAVLGFLPQLIILFLCLSFLEDCGYMARIAFFMDRLFRKFGLSGKSF
                     IPMLIATGCGVPGVMASRTIENEQDRRLTIMVTTFMPCSAKLPIIALVAGAFFPHQSW
                     VAPSAYFLGMTAIIFSGISLKKTRLFAGDTAPFIMELPAYHFPQWSAVLRQTYDRSKS
                     FVKKAGTIIFVSSIVIWFSSSYNFYAQPVSEDQSILAFFGRILAVVFQPLGWGNWQGT
                     VAAITGLVAKENIIGTFGILFGHAEVSENGREIWQVLQHTYTPAAAYSLLAFNLLCAP
                     CFAAIGAIHREMNAKKWTWIAIGYQCGLAYLVSFVIYQLGHLLEGGQVALGTYLAILL
                     MIGLVYVLFRQPKSKNQFYTILSLEGEE"
     gene            complement(7235..7708)
                     /locus_tag="LLC22_002097"
     CDS             complement(7235..7708)
                     /locus_tag="LLC22_002097"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319008.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferrous iron transport protein A"
                     /protein_id="HBK5435354.1"
                     /translation="MQTLAQAKQNFVYQVERIETEEKTKRHLQNIGIVAGSKIVVVNL
                     SGNNAILLVKSHRVAVSREILGQIFVNKKTASSESWTSLDQLKAGETGIVVAIHGQGA
                     VKRRLMDMGLTRNVKIVIRKLAPLGDPIELTVRGYELTLRKSEAELILIQREEKE"
     gene            8109..8333
                     /gene="nrdH"
                     /locus_tag="LLC22_002098"
     CDS             8109..8333
                     /gene="nrdH"
                     /locus_tag="LLC22_002098"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625075.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutaredoxin-like protein NrdH"
                     /protein_id="HBK5435355.1"
                     /translation="MNVKIFSKNNCMQCKMVKRFLTENQIAFEEVNIDEQPEAVDWLK
                     AQGFQSVPVITSDAETVIGFRPDQLRKLAS"
     gene            8492..10651
                     /gene="nrdE"
                     /locus_tag="LLC22_002099"
     CDS             8492..10651
                     /gene="nrdE"
                     /locus_tag="LLC22_002099"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310024.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit alpha"
                     /protein_id="HBK5435356.1"
                     /translation="MSLKNLQDVSYFKLNNEINRPVNGQIPLNKDKEALVAFFEENVK
                     PNTMTFPSIMEKINYLIDQEYIEAEFIQLYSPSFIEKLYQFLDEQHFSFKSFMAAYKF
                     YSQYALKTNDGSAYLETYEDRVAFNALYFANGDEELALALADEMIHQRYQPATPSFLN
                     AGRKRRGELVSCFLTQVTDDMNSIGRSINSALQLSRIGGGVGITLSNLREAGAPIKGY
                     EGAASGVVPVMKLFEDSFSYSNQLGQRQGAGVVYLNVFHPDIIAFLSAKKENADEKIR
                     VKTLSLGVIVPDKFYELTRKNEDMYLFSPYSVEKEYGVPFSYVNITAEYDHLVANPNI
                     RKQKIKARDLENEISKLQQESGYPYVINIDTANRENPIDGKIIMSNLCSEILQVQTPS
                     VINGKQEYEVLGTDISCNLGSTNIVNLMQSPNFGQSVRTMTRALTFITDASDIDVVPP
                     IQNGNKLNHTIGLGAMGLHTYLAKEQMEYGSEDSLDFTNIYFMLLNYWTLVESNNIAR
                     ERKQVFHNFEKSAYADGTYFEKYVTGEFQPKSEKVKALFEGIFIPTAEDWNALKQAVM
                     KDGLYHQNRLAVAPNGSISYINDTSASIHPITRMIEERQEKKIGKIYYPAPYLSNETI
                     PYYTSAYDMDMRKVIDVYATAQQHVDQGMSLTLFMRSEIPEGIYEWKTTTKQTTRDLN
                     ILRHYAFHKGIKSIYYVRTFTDDAEEIGSNQCESCVI"
     gene            10701..11666
                     /gene="nrdF"
                     /locus_tag="LLC22_002100"
     CDS             10701..11666
                     /gene="nrdF"
                     /locus_tag="LLC22_002100"
                     /EC_number="1.17.4.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625077.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class 1b ribonucleoside-diphosphate reductase
                     subunit beta"
                     /protein_id="HBK5435357.1"
                     /translation="MSETYYEAINWNEIEDIIDKSTWEKLTEQFWLDTRIPLSNDLDD
                     WRTLSQLEKDTVGHVFGGLTLLDTVQSESGMDQLRKDVRTPHEEAVLNNIQFMESVHA
                     KSYSSIFSTLNTKKEIEEIFDWTNTNPYLQKKAERINEIYKHGTPLEKKIASVFLETF
                     LFYSGFYTPLYYLGNNKLANVAEIIKLIIRDESVHGTYIGYKFQLGFNELPEAEQETL
                     KDWMYNLLYELYENEERYTEELYDPIGWTEEVKTFLRYNANKALMNLGMDPLFPDTAN
                     DVNPIVMNGISTGTSNHDFFSQVGNGYLLGHVEAMKDDDYLIGLE"
     gene            complement(11755..12894)
                     /locus_tag="LLC22_002101"
     CDS             complement(11755..12894)
                     /locus_tag="LLC22_002101"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5435358.1"
                     /translation="MQSRFKQSKLFFWTVELVLTIIGVYFILQMPNIFSPILKMLSAI
                     FLPLLVAGFIYYMFDPIVVFLEKHRIPRVFGFLLTFLVVIILVVLTVMNVVPQLMEQT
                     IQLTQSLPMYADETSKWLNELAQREEFKNFNLEEQLASANLSLSNLFNIILVSLSASV
                     SKIISFMMQFFILLFTVPFILLFMFKDGHKFIDALSHFFPKAIRKELRQTVKELNETL
                     SAYISSTILDALIIGVMSFLAMRIFDQPYSLLLAVICGITNIIPYVGPFIGAVPAIIV
                     GLFISPFQALYMALSILVIQQLDGNLIKPLLFGKSMNIHPLTIILVLIGAGSVAGILG
                     MLICIPVYAVIKTIILNIRKIYLLRRMEHVSEKLDSPKVLEETSE"
     gene            complement(13203..13916)
                     /locus_tag="LLC22_002102"
     CDS             complement(13203..13916)
                     /locus_tag="LLC22_002102"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MgtC/SapB family protein"
                     /protein_id="HBK5435359.1"
                     /translation="MNDMVLTIPEIILRLGIAMLFGGAIGFERQYKNRPAGMRTHILV
                     CMGACIIALIQVEIASGALRDALEYPQLAGTIRSDEARLIAQVVSGVGFLGAGTIIVT
                     KQSVTGLTTAASLWAIAGLGIAIGMGYYSIAIISFIGIAIALTVVKRVIHVPTTKKLE
                     IQFIHRKETKDFLTDYFEEKNIVIEDVNFDVKFVDDYRVYKNIYTIDLPKGLTYADVI
                     EELSVHKNITKLHLVSIAQ"
     gene            complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LLC22_002103"
     CDS             complement(14170..14871)
                     /gene="nagB"
                     /locus_tag="LLC22_002103"
                     /EC_number="3.5.99.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucosamine-6-phosphate deaminase"
                     /protein_id="HBK5435360.1"
                     /translation="MEIIRVKNAEEGGKKAFEIIKEGMNKGAKVLGLATGSTPVTLYK
                     EMTSSDLDFSEMTSVNLDEYVGLGGSDEQSYRHFMDVQLFDKKPFKETFVPDGKAEDL
                     EAACKKYDQIIDAHPIDIQILGIGQNGHIGFNEPGASFDGTTSVVDLTESTINANKRF
                     FDKAEDVPTKAVSMGIGSIMKSKEIVLMAFGESKADAIKGMIEGPVTNHLPASVLQNH
                     DNVVVIIDEEAASKL"
     gene            15105..16637
                     /locus_tag="LLC22_002104"
     CDS             15105..16637
                     /locus_tag="LLC22_002104"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310001.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F family ATP-binding cassette
                     domain-containing protein"
                     /protein_id="HBK5435361.1"
                     /translation="MSILTLNNITQQFGDKILYEGVDLQLNAGEHLGLIGQNGAGKST
                     LIKIITGEILPDDGQIHWQKNIHKGYLDQYVEVDETLTIEEFLKTAYAKEYEKEEKIA
                     FLYQTYSETFDDSLLEKAGKLQTELDQGVFYQIDTLVAEMSSGLGIDVLGLDSLLKNL
                     SGGQRSKVILAKLLLENPDVLILDEPTNHLDDQHIQWLTQFLQDFDGAYIVISHDQEF
                     LDQITTHIADIEFGKITKYTGHLKQALKQKEQNRESYLRQYHAQQKQIEKTEAYIRKY
                     KAGSRSTMAKSRQKQLDKIERLTPPASASKAVFDFPFSPIVTTLAVETTDLVIGYDRP
                     LLAPINLTIRFGENIAIRGFNGIGKSTLLKTLIGEIEKISGDFHFPDNTKINYFSQDL
                     YWENPLETPLQYLSSQFPKATIKELRRQLAKAGLVNQLASEPLTTLSGGEQTKVKLAQ
                     LTMNQGNLLILDEPTNHIDQETKESLQDGIQKFPGTVIIVSHEQEFYQDLVQRVIEIE
                     PK"
     gene            complement(16828..>17005)
                     /locus_tag="LLC22_002105"
     CDS             complement(16828..>17005)
                     /locus_tag="LLC22_002105"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5435362.1"
                     /translation="VFMFMYFIGGAAGSLLGTTMWQQYGWLGVTVSGLVFQGCAFFFQ
                     TVVFKGKRNLENKK"
BASE COUNT         5279 a         3494 c         2909 g         5323 t
ORIGIN      
        1 aaaaaacaca ttccactaaa tttgatgccg gttttccttg aggttttgtt ccagcacctc
       61 ctttaatttt tttaagctct tgatctgaac attgtttagc atttagtcta tttttttctt
      121 ccattacgat tccccctaca aactataaat acttttatgt cactgattca atatacctat
      181 ttttctaatc aaaaaatttt gagacatatt taatattata agtatcatta aaattgagat
      241 ttatctccat aatctgctcg atataaacca tttattccag cagttcttcc aatttcactc
      301 aaatttctta ttaattcctc ttgatattca gtgaatctta ttttattagt ataagcagta
      361 aaatatagat aattcaccaa tctatttatt aaaggactgg gatctaattc atatttttgt
      421 ttttctaatt ttaaatatac cttttgtaaa acctcaagaa tatcagaata tttaggatct
      481 ttacttatag atatatcatt atataattca tgaacaattt gcttagcatt ttttttcatt
      541 ttagcacttc cctggaattg ctccacctaa aaaaccacct atagacattc ctgcaataca
      601 agtagttgcc ttggcccaat cgaccgtaca tttattttta gtgcaataca ctccatttcc
      661 ataatatttt ccactatgag tggtaccccc atagataagt tgtgtctctt taatagacaa
      721 aatttttaaa tgtttcataa tctaatcacc cctaaattaa tgtttttaga ctattattct
      781 aacattcatt aaatttcaaa aaacaattcc ttcttgaaac gtagcaaaat aattcctgaa
      841 taagaattta atcactttta agtatataaa ctatgtatat tctttaatat tttttgagaa
      901 tgcacttcgt acataataaa ctttaatcac attagtcttt catacctacg atcgatctct
      961 ttgactcgca cccataaatt cataatagtt tgtcggcgtc tttgaacgtt tcgaagatga
     1021 gctacgcatt ctcttttttt atagacaaaa aagatagaga cgaacatgga gcttccaaat
     1081 ttggatattt gatccaattt tggaagctcc atttatttcg tgtctgtctt tttatttttt
     1141 ccagctttcg actaattctt ggttctcttt gatccagtct tttgctgctt gctgtggatc
     1201 ttttccattg ttgatttcca acataacttt ttccatatct ttttctgacc aatggaaatt
     1261 gtctaatact ttgtaagctt ctggctggtc ttctttcaat ccttttcgaa ccatcgtatg
     1321 gatctgctct tcgcttccca ttccgttttc aggatcttct aagtatttca gatcatattt
     1381 ggcaaacatc caatgaggtg tccatcctgt aactacaatt ggttcgtgtt ttttgatcgc
     1441 ttgacctagt gcaacggtca ttgctcctga agaagatgtc tctactttcc agtctttcaa
     1501 gttgtcatat ttttggatcg tgttttcagc agccgtaact acaccagctc ctggctcgat
     1561 tcctatgatt ttcttacctg cctgatcggt taactcatcg atcgaattta catccatgta
     1621 ggctggcact gctaaaccaa cttttgctcc tgtcaaattg gcacctaggt cttcgacttg
     1681 atctttatat tgtgcatatt gtgaaccatg agttttaggt agccaagctg aaaccatggc
     1741 atctgactcg ccatttgaaa cagatttcca catgattgaa ttatctaatg gcgtcatcgt
     1801 tacatcatag cccatttgtt tcaatacttc accgactaca tttgttgaag caacttctgt
     1861 atcccattca acataagata agttgatacg ttttgtttct ttggcagatg aaaaactccc
     1921 tataccaatc gcacctaaga tcactactac tacagcacca atgatcagtc cttgacgttt
     1981 tttacttttc tgtgttgttg ctcctgcagc ttttttattg tttggctggt tcaaatgctg
     2041 tgtaaaacgg tcaatgatga ttgctaagat aactaatgca accccgttga caaatccatt
     2101 cccgacttgt gctctttgca atgctgataa tacgccgcgt cctaagccgg gtgcaccgat
     2161 catagaggca ataacgacca ttgaaagtga cagcattgtt gtttgattga tccctgccat
     2221 gatcgtactt ttagctaaag gcaattctag tttgaatagt ttttgacgac ttgtgctccc
     2281 gaatgaatca gaagcttcta ctaattcttt aggaacttgt cgaatcccta aattcgtaaa
     2341 acgaacggtt ggtggcagag caaagatgac tgaggcaaat acccctggaa ccatcccgat
     2401 accgaaaaat gcaactgctg gaatcaaata aacgaatcct ggcattgtct gcataaagtc
     2461 aaggatcggt ttgataatac tttgggcttt actgcttttt gccatcaaga tccctaatgg
     2521 taccccaatg atgatcgaga tcacactaga taaaagaaca agtgtgacag tattcatcaa
     2581 atcattccat agaccttggt tataaataaa ccatagaccg attaatgtga acaacgtaag
     2641 tcctggacgt ttcttagaaa taaagaaagc tgctaccgtc aataacaaga taaacaaagg
     2701 agctggaatc actaacagta aatttgtaat ccccgacatc actgcctgtc caatcgtttg
     2761 taaaaatgaa aataggccag aaaaagttgt cgtaaaccat tctgtgatat tttctaccca
     2821 gtttgccact ggtaattgat agttcaatag attattcatg ttcactcacc tcgcttgttt
     2881 ctgctaatgc ttcaatcaca ctacctcgga tgacgacacc ttttaatttt ccatcctcta
     2941 caactgcaag tggagtcggt gagtcataaa taatattgaa aatatcactt accaccatgt
     3001 ctttcccaat caccgtcaca ttttcatcta ggaagtcgat caatggacgt ttttgcttcc
     3061 tagcttctaa cgcttgatct gcagtgatga tccctttcag gtgtctcttt ctgtcaacag
     3121 ccatcagcat gctgacttct tcattacgca tccttgtcaa tgcaacgttt ggtccatcag
     3181 attcgatatt cgtcgtcaat gcaggtacca tgatgttttg agccgtaagc actttggaac
     3241 gatcgacttc ttccacaaat tcacgtacat aatcatttgc tggattggtc aatatttctt
     3301 cacctgttcc gatctgcatg atttcgccgt ctttcatcaa ggcgattctg tccccaatcc
     3361 gtaaagcttc attcaaatca tgggtaatga aaataatcgt tttttgaaca ttggcttgca
     3421 ggtccagtaa ttcgtcttgc atttctcgcc ggatcagcgg atcaagagcc gagaacgctt
     3481 cgtccatcag caagatctca ggatcatttg ctaaagctct ggctaggcca acccgttgtt
     3541 gcatcccacc agataactga ctaggatatt ggtctttaaa tgaaagcaaa ctagaatttt
     3601 ctaatgcttt ttctgctttt tcttgtcgtt cttctttagg tacaccacgg acttctaacc
     3661 cgtattctgt attttccaag atcgttcgat gtggaaacag accgaagttt tggaaaacca
     3721 tattgatttt atgacgacgg acttctcgca attcttcttt gcttaacttc gatacatctt
     3781 ctccatcaat atagatactg cccgaagttg gctcaatcag acgattcaat agacggatca
     3841 atgtggattt cccactcccg gaaagcccca tgatcacgaa gatttctcct tcttttacgt
     3901 caaaattcac gtcatacaca ccaaccgttg caccggtttt ctttaaaatc tccgttttcg
     3961 gctggtgatc attcatcata tctaaagcgg cttgtgtctt tttaccaaat atctttgtta
     4021 aatgttttac ttctactttt accaaacaaa ttctcctttt ttatgtaaat tcatttttct
     4081 ttctgaaaaa agtgaccaca ctatgttaac atcatgtagt cactttgtca aaaatgaaag
     4141 aaatttgctt gtccaaactg aaaaaaactt ggctaaatct ttgtaaataa aaggtttagc
     4201 caagttaata tttttttaat atttcacaca atcattctgc aagctgatgc tccgggtaaa
     4261 aaaagtttgt catacgctgt agtgtatatt catttccaat aaaatgaacg atgtcccctg
     4321 ccgtaaattt agcatagggg ccaggtgaaa caagcagttc ttcattatga gaaattgcga
     4381 taactgtggc gccagtcgcc tgccagatat tcaactcgct aattgaacgg tccagatgca
     4441 ttgctttttc tgataaagat aattcaaacg gaagtaaagg attcatctta tgtattcgct
     4501 tcgtttgatt gaccagctga tccaataatt gagaaaaatg attcagctca tcttgttgct
     4561 tctccacact tgccatgatt tctgcttttg tatcttggat ggattgtaca tcttgatatt
     4621 gcaataggaa atcttttgct ttttccttcg aagcaacaaa tgccccactt ccatgccgta
     4681 cttccatgat tccaagatct accagcacat tgatagcctt gcgggtagtc tcaggagaag
     4741 cattgtacgt actggcaagt gttgagcggg catggatctt ctcacccact ttatatcggt
     4801 tttcaacgat acgttcggct aaatcaacag caatctgctg gtagcgcggg cggacgattt
     4861 ttttctttcc agacattttc tttcctcttt ctttttttac tttccctcat cttactatgc
     4921 tctagcaaaa taagcaaaaa aggggagaat agcctcttgc aacgactgat catcgcttga
     4981 tctgttcctt ttttactggg caagctgttt gacagtcatc acaattctta ccggatttta
     5041 aacgagtata gacaattgcg cctgcacttc caaagattaa cacacttaat aagaatgtcg
     5101 ccatcctatt cctctccttc taatgacaat atagtataaa actggttctt ggattttggc
     5161 tgacggaaca aaacataaac gagtcctatc atcagtaaaa tagcaagata cgtccctaac
     5221 gctacctgtc caccctccaa taagtgtccc aactgataaa tcacaaaact aactaaataa
     5281 gctaaaccgc attgatagcc tatggcgatc caagtccatt tcttggcatt catttcccga
     5341 tggatagccc caattgccgc aaaacaaggc gcacaaagta aattgaaggc taacaatgaa
     5401 taagctgctg cgggagtata tgtgtgttgt agcacttgcc agatttctct gccattttcg
     5461 gatacttccg catgaccaaa caaaatacca aatgtgccaa taatattttc tttagcgacc
     5521 aatcctgtaa tcgctgcgac tgttccttgc cagtttcccc aaccaagcgg ctgaaaaaca
     5581 actgccagga ttcgcccgaa aaaggctaag atactttggt cttcagaaac aggttgagca
     5641 taaaaattat aagaagagct gaaccagatc acgatactag aaacaaagat aatcgttcct
     5701 gcttttttaa caaaagactt gctgcggtca taggtttgtc ttaggaccgc tgaccattga
     5761 ggaaaatgat atgcgggcaa ttccatgata aaaggagctg tatctccagc aaacaaacgt
     5821 gtttttttca agctgattcc agagaaaata attgcagtca taccaagaaa ataggcagaa
     5881 ggagctaccc aagattgatg aggaaaaaag gcccctgcta ctaaggcaat aatcggcaac
     5941 tttgcagaac aaggcatgaa ggttgtgacc atgatcgtca aacgacgatc ttgctcgttt
     6001 tcaatcgtgc gactggccat gacgcctggc actccacatc ctgtagcaat cagcatagga
     6061 atgaaggatt ttcctgaaag accgaatttc ctgaaaagtc gatccatgaa aaaagcgatc
     6121 ctcgccatat atccgcagtc ttccagaaag ctcaagcata aaaacaatat aatcaattgc
     6181 ggtagaaatc ctaacactgc tcccacgcct gcgatgatgc cgttcaagat cagctcctgc
     6241 atccatcccg ctacttgcca ttcagctaac aatctgccaa catgttctgg taaccatgta
     6301 ccaaacaatg tgtcattgat ccaatctgtc cccattgttc ctactgtttg aatagccaga
     6361 taatagatca gccacatcac aaatgcgaag atcggcaagg ctaaccaacg attcgttgca
     6421 atctgatcga ttttgtcact catcgataat tggaaagaat catttgacac aacacagagt
     6481 gtacatagtt gggtaataaa ttcataacgt tcattgacca gaatcgtctc actatcgtcg
     6541 tccaatagtt tctctgttaa ctggatcagt tgctcgatct ctttttgctg agaaactgct
     6601 atctcgtaat cctctcttac cttctgatct cgttcaaaat atttcattgc ataccagcgt
     6661 ttcttgccgc tttgttctcc tagtacatct tcaatttcat gtaaagctgc ttctaaacgt
     6721 ggatcatatg tacagggaac aggaatagaa ggccgctttt ttgcagactc ctgaatcttt
     6781 tcgattagtt tttcgattcc ttgctttttc aatacgctga ttggtaaaac tggtacacca
     6841 agaccatagg aaagcttttc tagattgatt ttttttcctt cttttttgat gacatccatc
     6901 atattcagac caatgatcat aggaatgtct aaatccaata actgcgtagt taaataaaga
     6961 tttcgttcta aattggtagc atcaataatg ttgatgatca gttcaggctg ttcctgaacc
     7021 aaataatctc ttgcaatcac ttcttctggt gtataaggag acaaagaata gatgccgggt
     7081 aggtcctgaa tatgaatgtt cggatttttt ttcaacgatc cttctttttt ttctactgtt
     7141 acgcccggcc aattccctac atattgattc gaaccagtca agagattgaa caagctagtt
     7201 ttcccgctgt ttggatttcc gactaacgcg atattcattc tttttcctcc ctttgtatca
     7261 agattagttc ggcctctgac tttcgtaacg tcagttcata ccctcgcact gtcagttcga
     7321 ttggatctcc cagaggggct agttttcgga taactatttt tacatttcgc gtcaatccca
     7381 tatccattaa ccgtcgcttc actgcgcctt gtccgtggat tgctacgacg atcccagtct
     7441 ctcctgcttt taattgatca agagaagtcc agctttcaga ggaagcagtc tttttattga
     7501 caaagatttg acctagtatt tcccgactta ctgccactcg atgacttttt accagtaaaa
     7561 tggcattgtt gcctgataaa ttgacgacga cgattttact tccggcaacg atcccgatat
     7621 tttgcaaatg gcgttttgtt ttttcttctg tttcgattcg ttcgacttga taaacgaaat
     7681 tctgctttgc ctgcgctaag gtctgcatat tgattcctct cttgtgaaat aaatcatgta
     7741 ttaaaatcat tcattatatg ttctaatttt cttacgtgtt acgcaaataa atgagaatca
     7801 ttctcacata gaatactctc ggtaattgag aatgtcaatt atacttgtga tattatgagc
     7861 gaatctttag tattgataga taaaaatgag aaaaaaatat ttcttcatag ttttccacaa
     7921 ttttttctct attaaatttg ctattttccc acacgatact tgttttcagc tcttttttca
     7981 aaaacacaaa acttagtatt ccacagtttc cacaacacaa tatgtagtgt ttgttgtttg
     8041 acttttttac taagagtttt atactatcta ttatagataa taagaatgtg ttagaggagg
     8101 cactcaccat gaacgtaaaa atcttttcta aaaataattg tatgcaatgt aagatggtca
     8161 aacggttttt aacagaaaat caaattgctt ttgaagaagt caatatcgat gaacagcctg
     8221 aagcagtaga ctggttgaaa gcacaaggat tccaaagtgt tcctgtcatt acttctgatg
     8281 cagaaacagt tatcggattc cgtcctgatc agttgcgtaa acttgccagc taacatgact
     8341 aaaagaatca aaacgtgata catggatttg aagggcttga gacagcacca gtttttgtcg
     8401 caaacttcca aatccttttt taaagcttaa aaacaatgca atgatttgca atcaagcatc
     8461 atcaaatacg aaatgaaggt tgggcgtacg tatgagtctt aaaaatttac aagatgtcag
     8521 ttatttcaag ctgaataatg aaatcaatcg gccagtcaat ggtcaaatcc ctttgaataa
     8581 ggataaagaa gctttagttg ccttttttga ggaaaatgtc aaaccaaata cgatgacttt
     8641 tccatctatt atggaaaaaa tcaattactt gatcgatcaa gaatatatag aagcagaatt
     8701 cattcaattg tattcaccat catttattga aaagctatat caatttttgg acgagcaaca
     8761 tttttctttc aaatctttta tggctgctta caaattttat tctcaatatg cgttgaaaac
     8821 caacgacggt tccgcttatc tggaaactta tgaagatcga gtagccttca atgcgcttta
     8881 ctttgcgaac ggggatgaag aattagcact tgctcttgca gacgaaatga tccatcaacg
     8941 atatcagcca gctacacctt ctttcttgaa tgctggacgt aaacgtcggg gcgaattggt
     9001 gtcttgtttc ttgactcaag tcactgacga tatgaactct atcgggcgct caatcaactc
     9061 tgctttgcaa ttgtcccgta ttggtggcgg cgtagggatt actttatcaa atcttcgtga
     9121 agccggcgct cctatcaaag gatatgaggg tgctgcaagt ggtgtcgttc cagtcatgaa
     9181 attattcgaa gatagtttca gctattctaa tcaattaggt cagcgtcaag gagctggcgt
     9241 ggtttatttg aacgttttcc atccagacat tattgctttc ctttcagcaa aaaaagaaaa
     9301 tgcagatgaa aagattcgcg taaaaactct ttctcttggc gtgatcgtac ctgataaatt
     9361 ttatgaattg acacgtaaaa acgaagatat gtatttattt agtccatata gtgtcgaaaa
     9421 agaatatggt gtcccattct cttatgtaaa tattacagct gagtatgatc atctagttgc
     9481 aaatccaaac attcgcaaac aaaaaatcaa agcgcgtgat cttgaaaatg aaatctcaaa
     9541 attacaacaa gaatctggct atccttacgt aatcaatatt gatacagcga accgcgagaa
     9601 tccaatcgat ggcaagatca tcatgagtaa tttatgttca gagattttac aagttcaaac
     9661 gccttctgtg attaacggca aacaggaata tgaagtatta ggaacagata tctcatgtaa
     9721 cttaggctcg acaaatatcg tgaatttgat gcaaagccct aactttggtc aatctgtgcg
     9781 tacgatgact cgtgcattga catttattac agatgcatct gatatcgatg tcgtaccacc
     9841 gatccaaaac ggaaataagc tgaatcatac gattggatta ggtgccatgg gcttacacac
     9901 ttatcttgca aaagaacaaa tggaatatgg ctcagaggat tcattagact ttacaaatat
     9961 ttacttcatg ctgttgaatt attggacact tgttgaaagc aacaatatcg ctcgtgaaag
    10021 aaaacaagtt ttccataatt ttgaaaaatc agcttatgct gacggcactt atttcgaaaa
    10081 atacgtaact ggagaattcc agccaaaatc agaaaaagtc aaagcattgt ttgaaggcat
    10141 ttttatccca actgctgaag attggaatgc tttgaaacaa gcagtaatga aagatggact
    10201 gtatcatcaa aatcgcttgg cagtagcacc aaatggctca atttcatata tcaacgatac
    10261 gagtgcaagt attcatccta tcactcgcat gatcgaagaa cgccaagaga agaaaatcgg
    10321 taaaatttat tacccagcgc cttatctatc caatgagacg attccgtatt acacttctgc
    10381 ttatgatatg gacatgcgta aagtaatcga tgtttatgca acggcacaac aacacgtcga
    10441 tcaaggcatg agtttgactt tattcatgcg ttctgaaatc ccagaaggca tttatgaatg
    10501 gaagacaaca acgaagcaaa cgacacgtga tttgaatatt ttaagacatt acgctttcca
    10561 caaaggaatc aaatccattt attacgtacg tacctttact gatgatgcag aagaaatcgg
    10621 aagcaatcaa tgtgaaagct gcgtgatcta atatcataga tagattcgct tattcatatt
    10681 ttaattaaag gagcattctc atgtcagaaa catattatga agcaataaac tggaatgaaa
    10741 ttgaagatat cattgataaa tccacttggg agaagctgac agagcaattt tggctagata
    10801 cacgtatccc actttcaaat gacctagatg attggcgtac attgtctcaa ttggaaaaag
    10861 atacagtagg acatgtattt ggcggtttga cactgctaga tactgtccaa tctgaaagtg
    10921 gcatggatca gttgcgtaaa gatgtccgca ctccccatga agaagccgtt ttgaacaata
    10981 ttcaattcat ggaatccgtt catgccaaaa gttattcttc tatttttagt acactgaata
    11041 cgaaaaaaga aatcgaagaa atttttgact ggacaaatac gaatccttat ctgcaaaaaa
    11101 aagctgagcg tatcaatgaa atctacaaac acggtacacc gctagaaaag aaaattgcca
    11161 gcgtcttttt agaaacattc ttgttctatt caggttttta tactcctctt tattatttag
    11221 gaaacaacaa attggctaac gtagcagaga tcatcaaact aatcatccga gatgaatctg
    11281 tacatggaac ctacatcggt tacaaattcc aattaggatt caacgagtta cctgaagcag
    11341 aacaagaaac gttaaaagac tggatgtaca atcttcttta tgagctttac gaaaacgaag
    11401 aacgttatac agaagaatta tacgatccaa tcggctggac agaagaagtc aagacattcc
    11461 tacgctataa tgccaacaaa gcattgatga acctagggat ggatccactc tttccagata
    11521 ctgccaatga tgtcaaccca atcgtaatga acgggatttc aacaggcaca agcaaccatg
    11581 acttcttctc acaagtcgga aacggctatt tgttaggtca tgtagaagcg atgaaagacg
    11641 acgattattt gattggattg gaataaggat ttattttaat tcaaaaattt ttcgaaaaat
    11701 aaaaagagtt tagcgtacag atattttaaa tgtacactga actctttttt atgcttattc
    11761 acttgtttct tccagcactt ttggactgtc taacttttcc gaaacatgtt ccattcttct
    11821 caataaatag attttccgga tatttaatat tatcgtctta atcactgcat agacaggtat
    11881 gcaaatcagc atgcctaata ttcctgcgac acttcctgct ccaatcaata ccaagatgat
    11941 cgtcaaagga tggatattca ttgatttccc aaataacaac ggcttgatca aatttccatc
    12001 taattgttgg atcactaaaa tcgacaacgc catatacaaa gcttgaaatg gagagataaa
    12061 caaaccgaca atgattgctg gtaccgctcc aataaaaggg ccgacatacg ggataatatt
    12121 cgtgattccg caaatgaccg caagcaacaa gctataaggc tgatcgaata ttctcattgc
    12181 caaaaagctc attacaccaa taatcaaagc atctaagatc gtactgctga tataggcaga
    12241 taatgtttcg tttaattctt ttaccgtttg gcgtaactct ttacgaatcg ctttcggaaa
    12301 gaagtgagac aacgcatcaa taaatttgtg cccatccttg aacataaata gcaaaataaa
    12361 tggaacggta aataacaaaa taaaaaattg catcataaat gaaatgattt ttgagacact
    12421 tgcagataaa ctgactaata tgatattgaa caaattacta agagataaat ttgctgatgc
    12481 taattgttct tccaaattga aatttttaaa ctcttcccgc tgcgccaatt catttaacca
    12541 tttgcttgtt tcatctgcat acattggcaa gctctgggtc aattgaattg tctgttccat
    12601 taactgaggc actacattca tgacagttaa aacaactaaa atgattacga ccaaaaacgt
    12661 caataaaaaa ccgaacactc tcgggatccg atgcttttcg agaaaaacaa cgattggatc
    12721 gaacatataa tagataaaac cagcaacaag caatggtaaa aaaattgccg aaagcatttt
    12781 caatattgga ctaaaaatat tcggcatttg taaaataaag tacacgccga tgatcgtgag
    12841 tactagctcc actgtccaga aaaataattt tgattgttta aaacgtgatt gcatacatct
    12901 cctccaaggt cctttgatac ttctattcta tcatttaaca aagagttacg cgctgagatt
    12961 ttcatttgct taaaaaaaac aaaaaaaata aacatatttt aatgagtaga cgagtactta
    13021 aacaaaaaca cggtttggag tagtgacaaa aattatactg cagtcccttt ttccaaataa
    13081 acggtgttca aaagcttgca tcttcgtaat aagcccagcc aaacgaaaaa tataaggaac
    13141 tatttttatt tggctgggct tattacttga tgtaggacat ctattttaca acctcagatc
    13201 atttattgcg caatactgac taaatgcaac tttgtgatat ttttgtgtac ggacaactcc
    13261 tcgatcacat cggcataagt gagccctttt ggaagatcaa tcgtatagat atttttgtac
    13321 actcggtagt catcaacgaa ttttacgtca aaattcacat cttcgattac gatatttttc
    13381 tcttcaaaat aatcggtaag aaaatctttg gtttcttttc tatggataaa ttggatttct
    13441 aactttttag tcgtaggtac atggatcacg cgtttcacta ctgtgagtgc aatagcaatc
    13501 ccgataaaac tgatgatcgc aatggaatag taacccatgc cgatggcgat ccctaatcca
    13561 gcaattgccc ataaagaagc ggcagtcgta agtcccgtca ccgattgttt cgtgacgatg
    13621 atcgttcccg cgcctaagaa accgacacca ctcaccactt gagcaatcag ccttgcttca
    13681 tctgaacgaa tcgttccagc aagctgtgga tactctaaag catctcttaa tgcaccacta
    13741 gcgatctcaa cttggatcaa tgcaatgata catgctccca tacaaactaa aatatgcgta
    13801 cgcatacctg ctggacgatt tttatattgt cgttcaaaac cgattgctcc gccaaatagc
    13861 atagcgatcc ctaaacgtaa aataatctct ggaattgtca ataccatatc attcatctaa
    13921 acaccctcca gtccaatata tcatgtctga aaggagcaga caaaaaaagt gcaattttta
    13981 cctcttacga aaaaaggact gtgacaaaat ttttgtcata gtccttttta tgaataaacg
    14041 gtgttcaatc agctgaccct cggtattact caacaaacgg caaaatatgg ggagctattt
    14101 ttcctttgtc ttctctaata ctcaggtcaa aacgctgatt tcacaacctc tttagcctac
    14161 tattgaaaat tacaacttac ttgctgcttc ttcatcgatg atcacaacaa cattgtcgtg
    14221 attttgcaat acacttgctg gcaaatgatt cgttacaggt ccttcaatca tccctttgat
    14281 tgcatcagct ttgctttcgc caaatgccat caagacgatt tctttacttt tcataattga
    14341 accgattccc attgaaacag cttttgttgg tacatcttct gctttatcga agaatcgttt
    14401 gtttgcattg attgttgatt ctgttaagtc aactactgaa gtcgttccgt caaatgaagc
    14461 accaggttca ttgaaaccga tatgtccatt ttgcccgatt cctaagattt ggatatcgat
    14521 tggatgtgca tcgatgattt gatcatactt tttgcatgct gcttccagat cttctgcttt
    14581 tccatctggt acaaacgttt ctttgaatgg ttttttatca aataattgga catccatgaa
    14641 atgacggtag ctttgttcat ctgaaccgcc tagtccaacg tactcatcta agtttacaga
    14701 agtcatttca ctgaaatcca aatcgcttga agtcatttct ttatataaag taactggtgt
    14761 gcttcctgtt gccaatccta atacttttgc acctttgttc ataccttctt tgatgatttc
    14821 aaatgctttt tttccgcctt cttcagcgtt ttttacacga atgatttcca tagtgattgc
    14881 tcctttatat tttggtatag cccaattata gcattctttt tttcttttta caataattag
    14941 tatagaccaa attgcatttt tttcattttc ttgacaataa ataggaatcc gtgttaggtt
    15001 tcataagatg gttcaatcaa acaatccatg ttgcatgaaa accaagcaag tgattcactg
    15061 tggacgcttt atgtctgcag tttttttatg aaaaaggagt tattatgagt atactgacat
    15121 taaacaacat tacccagcaa tttggcgaca aaatcctcta tgaaggtgtc gatctgcaat
    15181 taaatgctgg cgaacatctt gggctgattg gacaaaacgg agccggtaaa agtacattga
    15241 ttaaaatcat cactggtgag atcttaccag atgacggaca gatccattgg caaaaaaata
    15301 ttcacaaagg ttacctcgat caatatgtgg aagtcgatga aacattaaca atcgaagaat
    15361 ttctaaaaac tgcgtacgca aaagaatacg aaaaggaaga aaaaattgct tttctttacc
    15421 aaacatatag cgagaccttc gatgattcct tgctggaaaa agctgggaaa ctccaaacgg
    15481 aattagacca aggagtgttt tatcaaatcg acaccttagt tgctgagatg agcagcgggt
    15541 tggggatcga tgtcttaggt ttagattcac tgttgaaaaa tctaagtggt ggacaacgtt
    15601 caaaggtgat tttagcaaaa ctacttttag aaaacccaga tgttctgatc ttagatgaac
    15661 caaccaatca cttagatgat cagcatatcc aatggctgac gcagtttctt caggattttg
    15721 acggtgcgta tatcgtgatt tcccatgacc aagaatttct tgatcagatc accacccata
    15781 tcgcagacat cgagtttgga aagattacta agtatactgg ccatctaaaa caagcattga
    15841 aacaaaagga acaaaatcgc gaaagctatt tgcgccaata tcatgctcaa caaaaacaaa
    15901 tcgaaaagac cgaagcttat attcgaaaat acaaagccgg ttcccgatca acgatggcaa
    15961 aaagccgaca aaaacaatta gataaaatcg aacggctgac gcctccagct tcagcaagta
    16021 aagctgtctt tgattttcca ttctcgccta ttgtcacgac attagcagtg gaaacaactg
    16081 atttagtcat cggatatgat cgaccgctac ttgcacccat caatttgacc atccgctttg
    16141 gtgaaaatat tgccattcga ggcttcaacg ggattggaaa atctacttta ttaaaaacac
    16201 tgatcggtga gattgaaaaa ataagtggcg atttccactt cccagataac acaaaaatca
    16261 attacttttc acaagatctg tactgggaaa atccattaga aacaccacta caatatttaa
    16321 gcagtcaatt tccaaaagcg actatcaaag aattacgtcg ccaactagct aaagcagggt
    16381 tagttaatca attagcaagt gaacctctca ctacattaag tggtggggaa caaactaagg
    16441 tgaaacttgc acagttgaca atgaaccaag gtaatttact gattctcgat gaaccgacga
    16501 accatatcga tcaagaaacg aaagaaagct tacaagacgg gatacagaaa tttccaggaa
    16561 cagtaatcat cgtctctcat gaacaagaat tttatcaaga tcttgtgcaa cgagtcattg
    16621 agattgaacc aaaataaacg tttgattgaa tagttgaaaa aaaggagctg tgacaaaagt
    16681 tttgtcacaa ctccttcttc tgaataaatg gtggccaatt agctgacctt cggtattagc
    16741 tcaaaaaacg gcaaaatatg aggagctatt tttatttggc tattcttatt acttgatgca
    16801 gaacagcttt tcacaacctc ttttcgtcta ttttttattt tcgagatttc tctttccttt
    16861 aaaaacaact gtttgaaaga agaacgcaca tccttgaaaa acaagcccgc taaccgttac
    16921 acctaaccag ccatactgct gccacattgt cgtccctagc aatgaaccag ccgcacctcc
    16981 aataaagtac ataaacataa ataca
//
LOCUS       DAFBVQ010000055        16903 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.057, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000055 DAFBVQ010000000
VERSION     DAFBVQ010000055.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16903)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16903)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16903
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.057"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..189)
                     /locus_tag="LLC22_002106"
     CDS             complement(<1..189)
                     /locus_tag="LLC22_002106"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334179.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435363.1"
                     /translation="MKEQRFDKNVYMEFFYWLYQSLASSLCFWCVNILYIAAAFLLSI
                     DGRNVFSFIFSLLFIGPGC"
     gene            complement(199..1014)
                     /locus_tag="LLC22_002107"
     CDS             complement(199..1014)
                     /locus_tag="LLC22_002107"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010731016.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carbohydrate ABC transporter permease"
                     /protein_id="HBK5435364.1"
                     /translation="MPFIQWLGMILLIVLALLTIIPFLWMVSASFKANNEVFTIPIQW
                     IPKTWHLENYLVIWSRIPLVTFFKNTAFLSVVITLIQLFTSSFAAYGFSKLNFKGRDI
                     LFLAYIGTIAVPWQSYMIPQFIMMRKVGLTYTLWSLVLLQAFNAFGVFLLKQYYSSIP
                     DSLCESARIDGLSEWGIYRKIILPLTKPAIASLTIITFVNTWNDYMGPFIYLSSTENK
                     TIQLGLKMFIGLFDAEYALIMAASVVSVLPVAFIFLAMQKYFVEGIASSGMKE"
     gene            complement(1276..1719)
                     /locus_tag="LLC22_002108"
     CDS             complement(1276..1719)
                     /locus_tag="LLC22_002108"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631212.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator
                     substrate-binding protein"
                     /protein_id="HBK5435365.1"
                     /translation="MLDPVDTEKYETILLPRKEKWGLLILENSVLAKKDVITKEDFAN
                     VPLLISKRPEIQRMFADWLGIKKEQLLITGTYNLIFNVFALIENQVGAALVIEGAVSH
                     LSKRVTFVPLDPMIETNCMLVWKKNRILSPVVNELIHRFKEAFEQ"
     gene            complement(1853..2191)
                     /locus_tag="LLC22_002109"
     CDS             complement(1853..2191)
                     /locus_tag="LLC22_002109"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321036.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5435366.1"
                     /translation="MYQVKKSRSIAMELRLLKYFWTIAEEGTISQAAEVLHLTQPTLS
                     RQLKELEEELGTELFVRENRKMILTEAGYFLKKPSRRNFRFNESNHSRIREQKKTIIQ
                     RPIYDRLCGS"
     gene            complement(2179..2556)
                     /locus_tag="LLC22_002110"
     CDS             complement(2179..2556)
                     /locus_tag="LLC22_002110"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302962.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MerR family transcriptional regulator"
                     /protein_id="HBK5435367.1"
                     /translation="MNIKQVSEEKGISADTLRYYERIGLIPPVNRTKGGIRDYTEEDL
                     KWVDFTICMRNAGLSIESLIEYIRLSSEGEATVFERRKLLIEESELLTKEIAEMQECL
                     ERLQGKIKKYDRVLSRNKMECIK"
     gene            2780..3973
                     /locus_tag="LLC22_002111"
     CDS             2780..3973
                     /locus_tag="LLC22_002111"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5435368.1"
                     /translation="MTTYQRKVLLSTSAGIALENMDIMFLAFSLSSMITSFHISGTQA
                     GFISTITNLGMLIGGIFFGIIADKYGRVKVFSQTVLLFSIASLLMYFASNIYLVYLFR
                     FIAGVGAGGEYGACMSLISESFSKKQIGRASSVAGIGAQVGAALAAILAAVIIPTFGW
                     KMLYVVGVLPVLMVLFIRRGLTEPKEFKSVQSAEKKTKLSRLFESKHLAWQTCGLSIM
                     VTVQIAGYFGLMNWLPSIMQNRLGLSVSGSSLWMVSTILGMSLGMMTFGIIMDKLGPK
                     LAFSLFLICSSLSVYLLVLAHSQWSLVAAAVIVGYFINGMYGGYGAVISSLYPTEIRA
                     TANNFIMNLGRAVGGFSSIVIGFLMDHYSLTAVILFLSGIYLVSLLVLTTLTGVTALR
                     ESLQH"
     gene            complement(4139..4561)
                     /locus_tag="LLC22_002112"
     CDS             complement(4139..4561)
                     /locus_tag="LLC22_002112"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435369.1"
                     /translation="MQTFLTKVSQKKIKMIHLLLETERWCSIEELQNELKVSSKSILN
                     YLTDLEELFQKYPDKVILKNENNRRFSMEKQENFPIYIIYLHFYRKSYNYHLIEFMYQ
                     HPEKNLEDYADAQYTSVSTVFRYAKLLVKYFEMTDVKE"
     gene            4956..5150
                     /locus_tag="LLC22_002113"
     CDS             4956..5150
                     /locus_tag="LLC22_002113"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321037.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435370.1"
                     /translation="MVAGSLLSGCGATTSTTQSTSSDQASSSSTTISESTADSSKEQE
                     QIEKKKEEKQKAEKAALEKK"
     gene            5147..5641
                     /locus_tag="LLC22_002114"
     CDS             5147..5641
                     /locus_tag="LLC22_002114"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348741.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435371.1"
                     /translation="MTEAESALSQAEANPTKENYATASAAIQALPENKQELTSRLAAI
                     DSTIKAKEAEEERKKQEEIARQQAEQAQQEAIAQQQAEQARQEAIAQQQAEQARQQSA
                     AEQASQQAQAAAPEQNNEQTVYVTPTGSKYHTHKCGNGTYTPATLSEAQARGLTPCSK
                     CYGN"
     gene            complement(5803..6975)
                     /locus_tag="LLC22_002115"
     CDS             complement(5803..6975)
                     /locus_tag="LLC22_002115"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333676.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class C sortase"
                     /protein_id="HBK5435372.1"
                     /translation="MNKSRIRILDIFMAIILVVGIGIFSYPFVEDSLNDFLAQQMIIH
                     YQKQASNKNSEEIKKQQEKMTKKNQQLAEQNVSPGIGSFNQAVDAKALKDLPSNAFFM
                     EHMLGVIEIPKINVSLPIFDQTTEIFLQKGTSLLEESSYPTGGKNTHAVLSGHRGLPE
                     AKLFTDLPKLKKGDQFFIQINGKTLAYQVEKIQVVLPDEVDSLGIQKGRDLVTLLTCT
                     PYMVNTHRLLVTGHRIPYQAKEAKKAIQGIDQWKKWKFFIWFIGILLGSIGLVWLLIA
                     YLDSLAIAKRNYPLSFYVKNTNGRPIEGMVFSVKTLNGKHYITREKVPFVKASDEYGL
                     VRFSDLKGRNYRLQHEELLLKIHVKHKHSKQFSMKLKKGRYKLRKEKEVYYLIEKE"
     gene            complement(7181..7996)
                     /locus_tag="LLC22_002116"
     CDS             complement(7181..7996)
                     /locus_tag="LLC22_002116"
                     /inference="COORDINATES: protein motif:HMM:NF033902.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SpaH/EbpB family LPXTG-anchored major pilin"
                     /protein_id="HBK5435373.1"
                     /translation="MTGFDENTGVALYDPAESALTFTTDTEGSISVNGLIDGNYTLVE
                     TKAPDGYQLTNPQKETTFIVKNGKLQQTTGIIHGADEANLGNPNGVVNRENTTTDNMI
                     TVENVQNYGDFHFIKQDVNTQEKLADAEFSILRAKDPTVKLMKKIANLASGEYPYAWS
                     DEVTGSDWEEVKLISDSEGKFSIEGLKQGAYCLQETKAPEGYALPKNEAAYTEFTVDD
                     DPTTSDETTIDNQPKGILPSTGGMGIIVFILVGTALVGGAVIYFKKRHQETEA"
     gene            complement(8146..8592)
                     /locus_tag="LLC22_002117"
     CDS             complement(8146..8592)
                     /locus_tag="LLC22_002117"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350079.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBK5435374.1"
                     /translation="MKNIKTKIWTFLGTAIMLLPFVLGLGTAEVSAAVSPTPENVTVN
                     LHKLKFTSAPENQINNGTELTFPNSEPLNGVEFNVYDITATYYPSKDTAVPADATPFA
                     SVTTSGEGLANLTLPGKSDGKDAVYVFVETPKPGVETSPNIVLSLP"
     gene            complement(8589..9593)
                     /locus_tag="LLC22_002118"
     CDS             complement(8589..9593)
                     /locus_tag="LLC22_002118"
                     /inference="COORDINATES: protein
                     motif:HMM:NF037639.1,HMM:TIGR04226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isopeptide-forming domain-containing fimbrial
                     protein"
                     /protein_id="HBK5435375.1"
                     /translation="MTDSSNHKLTTIHLYPKSEQKIPAALTLTKTVENKQTDFADGDK
                     VPYLITVTIPENINEIGTYTIKDTADPQLWLEPETIDFLIGGDKIHTFHTQKIKHGFV
                     LSDSGKDLSSFAGKKLTIRYQMTLKENSEKTTFDNDVRLTTDNQTVETHLAIQTGGKQ
                     FVKVDRQTKQKLADAQFLVKKNDQYLAQENGINHWVAKDDSRATIFTSSKDGTFSVHG
                     LSFGSYELVEIKPPKGYILSQSTILFEVEKGSYDPLHPIPLEIINEPKANPTNNGKTP
                     VQMQTNGPSNEKNGGSFPKTSEEMLGGFSILGLLLVLSTGTAWFYKKQQKGNNRREIK
                     "
     gene            complement(9633..9962)
                     /locus_tag="LLC22_002119"
     CDS             complement(9633..9962)
                     /locus_tag="LLC22_002119"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352916.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall anchor protein"
                     /protein_id="HBK5435376.1"
                     /translation="MFESDKMPSISQNDGINIPDNFQGVKGLNGVTFAIYDVSDEFYK
                     LRSEGSSVEDAQRKLAQKSDSEKILAENVTKTVDEEEGIASFSASDKDEQGRDAVYRF
                     TEIKTSD"
     gene            complement(10088..12415)
                     /locus_tag="LLC22_002120"
     CDS             complement(10088..12415)
                     /locus_tag="LLC22_002120"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303963.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5435377.1"
                     /translation="MKMIKKTQNKIQRICQKHFVSRLKAVSKRKYLHPIMISIILIFT
                     FLGSLSSIYVNVYTETSNFANQTTEETNSPPYSEIQSIESTNQSSNNETTSTTSSTQL
                     IDPTEKEITAAKAAGEKAYSETGRSQTFSTVAATANFNGHTIPDGYTVIYAKDGVIVA
                     VNGSMSADKTALQGVTKAIAFIDNRPDIHNLFIGSTVNGTTITFPKSIYMGVATAGNT
                     IDSVTPNADKSYSFTPSTWGGLPAGGGMSTFSIGIQLANDIPFTGYSIKNGQIVDGKG
                     NVSNFPTYQAATVQVNANRTGTFSYTVNGGAAKIGTYGTTLSGIHVGDKVVITPTAVT
                     GYSFAQTNGSFTALESNVDTVTYTGKQTPITIKYQDYFGQMIAPSKIMNLTYGSAAQD
                     LTTNTPTINGYTFTAVSAIETKNQSAMSVLASLDTNGNVIVKDANGKQISEVILYYKT
                     NATVSINANGSKYYDGLSVVPIVKYAFNDKTESTSLLNNDLSIDQITWNPTDFKAMNE
                     KGVEVTAPTEIGTYTSWQLTKSGLAKLAARTNYLFTIVQTSDVYTIKQISGAVELSGS
                     KTYDGKAGVPSIHVKLAEGVTSSLTPVQVALSSMDYTADAQSAKNMVNAGSYTIKLTN
                     SGIDKVKAANPKLSFTDIANTSGTYTIYKANAVITVDDAAFNYDAQSHSISVGNLHVT
                     GVVLGESLDYTLTVNSRTDIGSQIVTISLGEGSVNNNYTIIATDTAKLTINPTLLLPS
                     TGGIGLLPFVFLGLIFIFSGFFYFIHRKKKAGEQR"
     gene            complement(13258..13551)
                     /locus_tag="LLC22_002121"
     CDS             complement(13258..13551)
                     /locus_tag="LLC22_002121"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922289.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2087 domain-containing protein"
                     /protein_id="HBK5435378.1"
                     /translation="MVYTYTEQEKMKVLDTFMNDGKVKQVPSSTKKKYILLKEVLKRF
                     DHGVTYTETEVNSILLNVFSSGDYVEQRRYLITFGFFKRSSDGRAYQMMGIEN"
     gene            complement(13954..15132)
                     /locus_tag="LLC22_002122"
     CDS             complement(13954..15132)
                     /locus_tag="LLC22_002122"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354626.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5435379.1"
                     /translation="MEKTDRFKKQISSTGRITWYFQAYRTTRRGFNSKREAQLAYLEM
                     EKQQRLKKKIVASNDKFSVVGEQWFQYYRSLNEQKEITYDKREEQLKIIVRWIGDKKL
                     SDLTPECLQELLFTLKECGVNGTNVGYAKNSLQSLIQVLNMIFKYCQRKNLISENPMK
                     SVRMPKYQLTVTDLKEAINNIEDKFLTVDELRTFLNYGIVHEELPMSVLFHVLFYTGC
                     RVSEALALQPGDIDFKRNEILFYKQTAVKGKSKDFRIETTKTVSSARRVLVTPLVMEK
                     LQQLIKALGEMRQHYRFIIEETYLFVYLDSSKRGVPYRREYVNDHVKRCVNRSGINKP
                     FHTHLARHTMASLVAEHCSWEVLKDRLGHTDQTTSKIYRHLTSNEKVKPLIAFSSLES
                     "
     gene            complement(15236..15550)
                     /locus_tag="LLC22_002123"
     CDS             complement(15236..15550)
                     /locus_tag="LLC22_002123"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300928.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435380.1"
                     /translation="MELEVKTNVNSLEIEFYSILQKKLEDYTEKLLAVSHLPLVLTNT
                     DLKRLFQISDSTLNRLVKLGEFPPCWYGIRGHYFRDDVLEWMRKSDSNDYREKLRLLR
                     SL"
     gene            15657..15872
                     /locus_tag="LLC22_002124"
     CDS             15657..15872
                     /locus_tag="LLC22_002124"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435381.1"
                     /translation="MKQGIADIKIIKEILEKSTANAIAFGTGINLSTVKKLKSGERAE
                     EKLNLADAIKITEFGMKNMPTKIEIWK"
     gene            complement(16172..16414)
                     /locus_tag="LLC22_002125"
     CDS             complement(16172..16414)
                     /locus_tag="LLC22_002125"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288964.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435382.1"
                     /translation="MKQNKRYIPFIPLTTIKAAASGDSIAMSIVLSKYQNYISRLAMK
                     PVYEEEKGMVMYVDEYMRRQLETKLIEKILEFDTTR"
     gene            complement(16401..16829)
                     /locus_tag="LLC22_002126"
     CDS             complement(16401..16829)
                     /locus_tag="LLC22_002126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5435383.1"
                     /translation="MGDSEETHIQHTFDSFCKKVVCNEALNIQKKYARFRQRQISMEI
                     LEQKGLGTEFYYLEPNLNSSGTFIVLGMKIFISNEELANAIAALPSQRQEIIFMSFLI
                     GLNDREIGDIIGKSLGSVWYQRQMALEELGKYLGVKYEAK"
BASE COUNT         4927 a         3271 c         2936 g         5769 t
ORIGIN      
        1 gcaacctgga ccaataaaaa gtaaagaaaa aataaaggaa aagacattcc ttccatctat
       61 cgacaaaagg aacgcagctg ctatatacaa gatattgaca caccaaaaac aaaggctact
      121 tgccaatgat tgatacaacc aataaaagaa ttccatataa acatttttgt caaaacgctg
      181 ctctttcata atcacctcct attccttcat tcctgatgaa gcgatccctt ctacaaaata
      241 tttttgcatc gctaaaaata taaaagcaac aggaagaaca gaaacaactg aggcagccat
      301 gattaatgcg tactctgcat caaatagccc aataaacatt ttcaacccta actggattgt
      361 tttattttcc gtagaagaca aataaatgaa tggccccata taatcgttcc atgtattaac
      421 gaatgtgatg atcgtcaaac tggcaatcgc cggttttgta agaggtaaaa tgatcttgcg
      481 atagattccc cactctgata agccatcgat ccgcgcactc tcacataaag aatctgggat
      541 actactgtag tattgcttca acaagaacac accaaaagca ttgaacgctt gtaatagcac
      601 caacgaccac aacgtatatg ttaaacccac ttttctcatc ataatgaact gcgggatcat
      661 ataagactgc caagggacag caatcgtgcc gatatatgct aaaaataaaa tatcgcgccc
      721 tttaaaattt agtttagaaa acccgtaagc agcaaaacta gaagtaaaca actgaatcaa
      781 cgtgatcaca acgcttaaaa aagctgtatt cttaaaaaat gtcactaaag gaatacgaga
      841 ccaaataacc agataattct ctaaatgcca agttttaggg atccattgaa tcggaatcgt
      901 gaacacttca ttatttgctt tgaatgaagc agaaaccatc cataaaaaag gaatgatcgt
      961 caataaagct aatacaatca gcagaatcat acccaaccat tgaataaagg gcatgttttt
     1021 tgaacgaatt tttgcttttt ttctttcatt tcgaacacct ccaaagttat aatcttcatt
     1081 tctttgtaat gattacaatc cagaacaacg gttattatag ctgattcatt tccgttcttc
     1141 ttatgtttgt aagcgcttat ttaacaagtt atgtaaatct ctttattttt tttgatttaa
     1201 aaatgaaaaa atacaaaagc aagactgtca tacgtctcgc ttttgtattg aaatttcttc
     1261 gattagagat acttattact gttcaaaagc ttctttgaaa cggtgaatca attcattgac
     1321 tacaggtgat aaaatccgat tctttttcca gactagcatg cagttcgttt caatcattgg
     1381 gtcaagcgga acgaatgtca ctcgctttga aagatgactt acagcacctt ctatgactaa
     1441 agcagcacct acctgattct caattagcgc aaatacattg aaaatcaaat tgtacgttcc
     1501 tgtgatcagc aactgctcct tttttatgcc taaccagtca gcaaacattc gctgtatttc
     1561 tggacgcttt gagatcaaaa gaggtacatt cgcaaagtct tcttttgtta tcacgtcttt
     1621 ttttgctaaa acagaatttt ctaaaatgag caatccccat ttttcctttc ttggtaacaa
     1681 aatcgtttcg tatttctctg tatctactgg atctagcaaa atcgctaaat ctaacaggct
     1741 tttttctagt cactccgtga tatcatcact tgttccgctg tggatatgaa attgaacgct
     1801 gggataatca cggatcaact tttctagtaa tagtgccaat gtattcgaat tatcagcttc
     1861 cacacagccg atcgtaaatc ggccgctgaa taattgtttt tttctgttct cgaattcttg
     1921 agtggtttga ttcgttaaat ctaaaatttc ttctgctcgg cttttttaga aaataacctg
     1981 cttctgtcaa gatcattttg cggttttcgc gtacaaacag ttctgttcct agttcctctt
     2041 ctaactcctt cagttgtcgg cttaaggttg gttgtgtaag atgtagaact tctgcggctt
     2101 gagagattgt tccttcttct gcaattgtcc aaaaatattt tagtaagcgt aactccatag
     2161 cgatgctcct tgattttttt acttgataca ttccatttta tttctagata acacacgatc
     2221 atatttcttg atttttcctt gtaaacgttc caaacactct tgcatttcag caatttcttt
     2281 cgtcaaaagt tcactttctt caatcaaaag cttacgccgc tcaaatacag ttgcttctcc
     2341 ttcgctagat aggcgaatat attcaatcaa agactcgatc gataatccgg catttcgcat
     2401 acagatcgta aagtcgaccc attttaggtc ttcttctgta taatcacgga ttccgccttt
     2461 tgtccgatta actggtggaa tcaacccgat tcgttcataa tagcgcaatg tatcggccga
     2521 aatgcccttt tcttcactga cttgtttgat attcatctga tcactctttc tcttaatttc
     2581 ttgccacttt acttatgtat tttatttatt ctacaacttt aagtgtactc caagtcaata
     2641 ctcatttcta ttaaaactaa gctggattat ctatatcggt tgtttgtgta ttatttcaaa
     2701 taaaaaagtc ttgttttttt attctttttt ggatatactt ttaacaattt agggaaattt
     2761 taggaaaagg ggtataaaaa tgacaacgta tcagcgaaag gtattattat cgacatcggc
     2821 gggaattgct ttagagaata tggatattat gtttttagct ttttcattat cttcaatgat
     2881 tacttctttt catattagtg gtacgcaagc gggtttcatt tcaacgatca ctaatttggg
     2941 gatgctcatt ggaggtattt tttttggcat catagctgat aaatatggac gtgtgaaagt
     3001 attttctcaa acggtccttc tgttttcgat tgcttcttta ttgatgtatt ttgcttcaaa
     3061 catctacttg gtttatctct ttcgctttat cgcaggtgta ggagcgggag gagaatacgg
     3121 ggcgtgtatg tccttgattt ccgaaagttt ttcaaaaaaa caaattggac gagcttcttc
     3181 ggttgctggt attggtgcgc aggtcggtgc ggctttggct gcgattttag ctgctgtgat
     3241 cattccaacg tttggttgga agatgttgta tgtcgtaggt gtactgccgg tgttgatggt
     3301 cttgttcatt cgtcgcggct tgactgaacc aaaggaattc aaatctgtac aatctgccga
     3361 aaagaaaacc aaacttagca gactgtttga atcaaaacat cttgcttggc aaacatgtgg
     3421 ccttagtatc atggtaactg tccaaattgc cggctatttt gggttaatga attggctgcc
     3481 ttcaattatg caaaatcgat tagggctttc ggtttctggg tcttcattgt ggatggtcag
     3541 tactatttta ggcatgtctt tggggatgat gacttttggc ataatcatgg ataaattggg
     3601 gcctaaacta gccttttctt tgtttttaat ttgttcatcc ttatctgtct atctacttgt
     3661 gttagcccat agccagtgga gtttggtagc agccgctgtg atagtcggct actttatcaa
     3721 tggcatgtat ggtggatatg gcgcagtgat tagtagtttg tatccaacag aaatccgcgc
     3781 gacggcgaat aatttcatta tgaaccttgg acgagctgtt ggtggttttt cttctatcgt
     3841 catcggtttc ttgatggatc attatagttt aactgccgta atcttgtttt tgagcggtat
     3901 ttacctagtc agtctgctgg tcttgacaac tcttactggt gttacagcat taagggaaag
     3961 cttgcagcat tgatagttga gtctgtaaat gacaagaaag aggtgtggca aaagcttgca
     4021 tctgcggtaa taagaccagc caaatcaaaa acatgagaca ctgtttccgt ttggctggtc
     4081 gtattacttg atgcagggca gctttttcaa ctgctaattt ccttctatct ggcggcgact
     4141 attctttgac gtccgtcatt tcaaagtact ttactaataa cttagcataa cgaaaaactg
     4201 tggatacact cgtatattga gcgtctgcat aatcttccaa atttttctca ggatgttgat
     4261 acatgaattc aatcaaatga taattatatg attttctgta gaaatgaaga taaataatgt
     4321 agattgggaa gttctcctgc ttttccatag aaaagcgccg attattctca ttcttcaaaa
     4381 tgaccttatc aggatatttt tggaacaatt cttctaaatc tgttagataa ttcaagatag
     4441 acttacttga taccttcaat tcgttttgta gttcttctat tgaacaccaa cgttctgttt
     4501 caagcagtaa atgaatcatt ttaattttct tttgagaaac ttttgttaaa aaagtctgca
     4561 tattttctcc tcctgtatct actttactat actacataca agaaaaaaaa cggatacaaa
     4621 tatcatattg tcacaccgtc aatagtgcat aaacctgtta ttatttctct ttttttccta
     4681 agtattctat tgatatgaat catttaatcg tttattatat aaatgtcaat aatctaataa
     4741 taaaataacg tacatatttt attattgcat acttaataac agaactatag caaaaaatcc
     4801 cgtgtatcaa cacgggatta gattaagttt cctcaatcac tattcataac acaattatta
     4861 taacaagtaa gtaaacaatt gaaaaggaca tttattgaaa acggttgttt tttacttaag
     4921 gaggaaattt agcgaaaaaa ttagttgcat tgtttttggt cgcaggaagt ttgttgagtg
     4981 ggtgtggtgc tactacgtct actactcaaa gcacaagttc agatcaggct tccagcagca
     5041 gtaccacgat ctccgaaagt acggcagatt catcgaaaga acaagaacaa attgaaaaga
     5101 aaaaagaaga gaaacaaaaa gcggaaaaag ctgcactaga aaaaaagtga cagaagcgga
     5161 atctgctttg tcacaagctg aagcaaatcc tacaaaagaa aactatgcaa ctgcttcagc
     5221 agctatccaa gcgctacctg aaaacaaaca agagttgaca agccgtcttg ctgcaattga
     5281 ttccacaatc aaagcaaaag aagcagaaga agaacggaaa aagcaagaag aaattgcacg
     5341 acaacaagca gaacaagcgc aacaagaagc aatcgcacag caacaagcag aacaggcgag
     5401 gcaagaagca atcgcacagc aacaagcaga acaggcgcga cagcaatcag cagctgaaca
     5461 ggcctctcag caggcacaag ccgcagctcc tgagcaaaat aatgaacaaa ctgtctatgt
     5521 cacaccgacc ggttcaaaat accatacaca taaatgtgga aatggtacgt atacccctgc
     5581 cactttaagc gaagctcaag ctcgtggttt aaccccttgc tccaaatgtt atggaaacta
     5641 attcaaaagt tatactataa taataaaatt cttctgaaac ataaaaaaat agaagatggc
     5701 gttccagata gtaaaccaaa aataacagtt tacacgtcca tttcgtcagc ttctctcttt
     5761 tttcatttag tctgttccct ctgctttttt ggacatcttc attcattctt tctcaatcaa
     5821 atagtacacc tctttttctt ttcgcagttt atatcttcct tttttcaatt tcattgaaaa
     5881 ctgtttcgaa tgtttatgtt ttacatggat tttaagcagg agctcctcat gttgcaagcg
     5941 atagttcctg ccttttaaat cagaaaatct cactagtccg tattcatcag aagctttcac
     6001 aaatggaact ttttctctag taatatagtg tttgccgttg agcgttttta cagaaaagac
     6061 cattccttcg attggtcgtc cgtttgtgtt ctttacataa aaagataaag gatagtttcg
     6121 cttagcgatg gccaaagaat ctaaataagc gatgagtagc caaactaagc cgattgatcc
     6181 aagtagtata ccgataaacc aaataaaaaa tttccatttt ttccattgat caattccttg
     6241 gatcgctttt tttgcctctt ttgcttgata aggaatacga tgccccgtca caagcagtcg
     6301 atgtgtattg accatataag gagtacaggt aagcaaagtc acgagatctc tgcctttttg
     6361 gatacccaaa gaatctactt catcaggtaa gaccacttgg attttttcta cttgatacgc
     6421 caatgtcttt ccattgatct ggatgaaaaa ctggtctcct tttttcaact taggcaaatc
     6481 tgtaaataat tttgcttctg ggagtccacg atgcccagaa agaacggcat gggtgttttt
     6541 cccgccagtc ggataagaac tttcttccaa taatgacgtt cctttttgca aaaatatttc
     6601 cgttgtctga tcgaatatag gtaagctgac attgattttt gggatttcga tgactccaag
     6661 catatgttcc ataaaaaagg cattactagg taaatctttt aatgcttttg catcaactgc
     6721 ttggttgaaa ctgcctatcc ctggtgatac gttttgctct gccaactgtt ggtttttctt
     6781 tgtcattttt tcctgctgtt tttttatttc ctctgaattc ttattcgatg cttgcttttg
     6841 ataatggatg atcatttgct gggcaagaaa atcattcagt gaatcttcta caaaaggata
     6901 agaaaagatc ccgatcccaa cgactaaaat gattgccatg aagatgtcca gtattcttat
     6961 tctgctttta ttcatcatgt ccacctattt tctaatatgt atatgaagag gttgtgaaat
     7021 cagcgccttg acctgagtat tagcgaagca aacggcaaaa tagttcctcc tattttgccg
     7081 tttgttgagc gaataccaag agaccgacca cttgtcacaa cctttctccc catttgaatc
     7141 actatcgttt atttatcgta tgatttttgt ttccaatagt ttaagcttct gtttcttgat
     7201 ggcgtttttt gaaatagatc actgctcctc caactaaagc agtacctacc aagatgaata
     7261 cgatgatccc cataccacca gttgaaggca agattccttt aggttggtta tcgatcgttg
     7321 tttcatcaga agttgttgga tcatcatcta ctgtaaattc agtgtacgca gcttcattct
     7381 taggtaatgc gtagccttct ggtgcttttg tttcttgaag gcagtatgcc ccttgtttca
     7441 gcccttcgat tgaaaatttc ccttctgaat cagaaatcaa tttcacttct tcccagtcag
     7501 aacctgtgac ttcatctgac caagcatatg ggtattctcc tgaggcaagg tttgctattt
     7561 ttttcattaa tttaacagtt ggatcttttg ctcttagaat agaaaattct gcatcggcta
     7621 atttttcttg cgtgttcaca tcttgtttga tgaagtggaa atcaccgtag ttttggacat
     7681 tttctacagt aatcatgtta tccgtagttg tattttcccg attgactaca ccgtttggat
     7741 tcccaagatt ggcttcatct gcgccatgga tgataccggt tgtttgttgc aattttccgt
     7801 tttttactat aaaagtagtt tctttttgtg gattggttaa ttgataacca tctggtgctt
     7861 ttgtttcaac taaagtataa ttgccgtcta ttaatccatt gacactgatg gatccttcag
     7921 tatcagttgt gaatgtcaac gctgactcag caggatcata gagagcgaca ccagtgtttt
     7981 catcaaaacc ggtcacgaat tgattctctg aatttttgat ctggaattgc gcccctgcta
     8041 acttatctac ccctgaaaag ttcccagctt tctggatttt gatattgctt tctttgatga
     8101 catttttagc atataggtga atcgtgtcta aaggtttgtc agggtctagg gtaagcttaa
     8161 cacgatattt ggcgacgttt cgacaccggg ctttggtgtt tctacaaaga cgtatacagc
     8221 atctttccca tcagatttac ctggaagagt caggttagct aatccttcac cagaagtcgt
     8281 tacacttgcg aagggtgtag cgtctgctgg aactgctgtg tctttacttg gatagtacgt
     8341 agcagtgatg tcatatacgt tgaattcaac gccgttcaac ggttcgctat tcggaaatgt
     8401 caattccgtt ccgttgttta tttgattttc tggtgctgaa gtgaatttca atttatgcaa
     8461 attaaccgta acattttctg gtgtaggtga tacggctgca gaaacctctg cagttcctag
     8521 gccgagaacg aaaggaagca gcatgatagc agttcctaaa aacgtccata tttttgtttt
     8581 gatgtttttc attttatttc cctcctattg tttccttttt gttgtttttt ataaaaccaa
     8641 gctgtccctg ttgaaaggac tagcaataac cctaaaattg agaaacctcc aagcatctct
     8701 tcgcttgttt ttggaaagct tcctccattt ttttcatttg atggaccatt tgtctgcatc
     8761 tgaactggcg tttttccatt attcgtcgga tttgcttttg gttcgttgat gatttccaat
     8821 ggtataggat gaagcggatc ataactgcct ttttcaactt caaagagaat ggttgattga
     8881 ctcaatatat atcctttagg cggtttaatc tccactagtt cgtaacttcc aaaagacaat
     8941 ccatggacag aaaatgttcc atctttactg gaagtaaaaa tcgttgctct tgaatcatct
     9001 ttggctaccc aatgatttat cccgttttct tgcgctaagt attggtcatt ttttttgact
     9061 agaaattgag catctgctag tttttgtttc gtttgccgat ccactttgac aaattgtttg
     9121 cctcctgttt ggatggcaag atgtgtttct actgtttgat tgtcagtcgt caaacgtaca
     9181 tcgttatcaa atgtcgtttt ttcactgttt tctttcaatg tcatttggta acggatcgtt
     9241 aatttttttc cagcaaacga actaagatct tttccagaat ctgataagac aaaaccatgt
     9301 tttatttttt gtgtgtgaaa tgtatgaatc ttgtctccac caatcaaaaa atcgatcgtt
     9361 tctggttcta gccataactg aggatcagct gtatctttga tcgtataggt tcctatctcg
     9421 ttgatgttct caggaattgt tacggtgatg agataaggga ctttatcccc atctgcaaaa
     9481 tctgtctgct tattctctac tgtttttgtt aatgtgagtg cagcaggtat tttttgttcg
     9541 ctctttggat acaagtggat ggtcgtcaat ttatgattag atgaatctgt cacaggaagc
     9601 acaacgacaa atggtgctga tttttctttt acttaatctg aagtctttat ttccgtaaat
     9661 cggtaaacag cgtcacgacc ttgctcatct ttgtccgatg cactaaaaga agcaatgccc
     9721 tcttcctcgt ctactgtttt tgtcacattt tctgccagta ttttttcact atcacttttt
     9781 tgtgctagtt ttctttgtgc gtcttccaca ctacttcctt ctgaccgcag cttgtaaaat
     9841 tcatccgaga catcatatat agcgaaagta acgccgttca acccttttac tccttgaaag
     9901 ttatccggga tatttattcc gtcgttttga ctgatacttg gcatcttatc gctttcgaac
     9961 attcgattat gcaaagtaaa tgtaataggt gattctctag ctgacacagt cggagaacct
    10021 ataaaaaaga ccagtaggat aaaaaagaga acagcaaata tatccacacg tacatttttt
    10081 gtttttttca tcgctgttca cctgcttttt tcttacgatg gataaaataa aagaagccag
    10141 aaaaaataaa gatcagtcct aaaaagacaa agggcagtag acctatccca cctgtcgaag
    10201 gaagcaagag agtcggattg atcgtcaact tagcggtatc tgttgcgata atcgtataat
    10261 tattgtttac acttccttcg cctaaactaa tcgttactat ttgtgatcca atatctgtcc
    10321 ggctgttaac tgttagggta taatccaatg attcgcctaa gacaacaccg gtaacgtgga
    10381 gatttccaac cgaaatcgag tgactttggg catcataatt aaaggcagcg tcatcgacag
    10441 taatcactgc gttagcttta tagatggtat aagttcctga tgtgttggct atatcagtaa
    10501 atgacaactt gggatttgct gctttgactt tgtctattcc gctattcgtt agtttaattg
    10561 tatagctgcc agcattaacc atattttttg ctgattgtgc atctgctgtg taatccatac
    10621 tgctaagtgc cacttgtact ggagtaagcg aactagtgac accctctgct agcttgacat
    10681 ggattgacgg gacacctgct tttccatcat atgtcttact gccactgagc tctaccgcac
    10741 cgctgatttg cttaatcgta tagacatcag atgtctgcac gatagtaaat aaatagtttg
    10801 ttctggcagc tagtttagct agtccgcttt ttgtcaattg ccaagacgta taggttccaa
    10861 tttcagtagg cgcagttact tcaactccct tttcattcat cgctttgaaa tcagttggat
    10921 tccatgtgat ttgatcaata ctgagatcat tgtttaaaag ggatgttgat tctgttttat
    10981 cattaaaggc atatttaacg atcggtacaa cagaaagacc atcatagtac ttactgccat
    11041 ttgcattgat tgatactgtt gcatttgtct tataatatag gatgacttca gaaatctgtt
    11101 ttccatttgc gtcctttacg attacatttc catttgtatc taaactagct aaaacactca
    11161 ttgctgattg gttctttgtt tctatcgctg aaacagctgt aaaggtatat ccgttgatag
    11221 taggcgtatt agtcgtcagg tcttgtgcag cacttccgta agtaagattc attattttag
    11281 aaggagcaat catctgtcca aaatagtctt gatacttaat agtgattggt gtttgtttgc
    11341 ctgtataggt caccgtatcg acgttacttt ctagggctgt gaaagaaccg tttgtttgtg
    11401 caaaagaata gcccgttact gctgttggag tgataaccac tttgtcaccc acatggattc
    11461 cagataatgt agtcccgtac gttccgattt ttgctgctcc accattgact gtataagaaa
    11521 aagttcctgt ccgattcgca ttgacctgaa ccgttgctgc ttgataggtt ggaaaatttg
    11581 aaacatttcc cttaccatca acgatctgcc catttttgat cgagtacccc gtgaatggaa
    11641 tatcatttgc taactgtata ccgattgaaa aagtactcat acctcctccg gcaggaagcc
    11701 ctccccatgt tgagggtgta aaagaataac ttttatccgc attgggtgta actgaatcga
    11761 tcgtatttcc agcggtagcc acccccatat agatactttt tgggaatgtg atagtagtac
    11821 catttactgt ggagccaata aacagattat ggatatctgg acggttatca ataaaagcga
    11881 ttgctttggt tacgccttgt aacgcagttt tatccgcact catcgatccg ttaaccgcaa
    11941 caatgactcc atctttggca tatatcactg tatatccatc tggtatggta tgtccgttga
    12001 aattcgcagt ggccgcaaca gtactaaatg tctggcttct acctgtttct gaataagctt
    12061 tctcccctgc tgcttttgct gctgtgattt ctttttctgt cggatcaatc agttgagtcg
    12121 aggatgtggt tgaggttgtc tcgttgttgc tagactgatt ggtgctttct atggactgta
    12181 tttcagaata gggtggacta tttgtctcct ctgtcgtttg gttagcaaaa tttgacgttt
    12241 ctgtataaac gtttacataa atacttgata agctccctaa gaaagtaaaa atcaagatga
    12301 tcgaaatcat aatgggatgt aagtattttc ttttagatac agctttgagt ctagaaacaa
    12361 aatgtttttg acatatacgt tggattttat tttgagtttt cttaatcatt ttcatccctc
    12421 ctctcaataa aaaatcatca aataatcctt tacacgttat tctaaattta atttttatta
    12481 ttttattgat gtatagaaag tttggggctt tttttctctt tttattctaa ggttatttta
    12541 gtcttgtcct ttaatacaaa gattttattt ttaaataaaa aatactcttt ttttacgatt
    12601 attgaaaaaa aaagataaaa cttgattaat tgaagtattg cttaaatttg gaagctatga
    12661 gggaagaata aaagagttag gacgggatta tctactattt ttctttgttt taaatatttg
    12721 ttatctttga acataaaaga gaaatgtgtc gactgcagtg ttgtgtccct catcacgaat
    12781 aaacggtgtt caattagctg atcttgtatt cacttaaaaa atggtaaagt acgagttgct
    12841 attccccatt ttcaattttc taacgctcag gacaaaatac tgttttcaca acctcattgg
    12901 aataaaagca tatatattgt ttcaagaacg aaatcttgtt atctttttaa agggcatctg
    12961 tccaaaatct aattttagga ggtacgtttt ggtatttatt cgtacaaata aaagagaatt
    13021 atctttattc atgtaacgca tccaattgat tttttcatgt acgctcctgg aacgatttta
    13081 ctgacgattg cttatttaac tgcgaatcgc tcattagctt ttatcatagc tatccatatt
    13141 ttgaataacg ttcttggctt tgtattatag atacagatga caaaaaaagt tcaagtatgc
    13201 ggtgtagaac caatatcgca tacttgaact tttttcaatg agtataaatt aaaacttcta
    13261 attttcaatt cccatcatct gatatgcccg accgtctgaa cttcttttga aaaagccaaa
    13321 tgtgattaga taacgtcttt gttcgacata atcgccacta gaaaatacgt tcagcagtat
    13381 cgaattaacc tctgtttctg tataagtcac tccatggtca aagcgtttca agacttcttt
    13441 caataggatg tatttctttt ttgttgaact tggtacttgt tttacttttc catcattcat
    13501 gaatgtgtct aaaactttca tcttttcttg ctccgtataa gtataaacca tcttctttct
    13561 ccttttgatt ctaagaatac tccatttatg ttagaatatt ctggattttt tattaaagcg
    13621 gttactctta agaaagatat tatcatagtg ctcttttttt tactactact tataggtaga
    13681 tttattctaa tccattattc tcccctacca ataattaaag aaaaaactgg atcagggtgt
    13741 tcaaattaca tgctaagaaa aaagaaccct tgaataccaa gggttctttc tcagtctgat
    13801 aacaatgatt aacgacggat ttctttgata cttgtgaaaa gtcgttaaag tattgatata
    13861 aaaggatttt tattacctct gactacatat tgactaattt gttaaaaaat cgtttttcaa
    13921 gaatcctgta ataccagtgc tttcaccgtt tttttaactc tctaaagaac taaaagcaat
    13981 cagaggtttt accttttcat ttgacgttaa gtggcgataa attttcgaag ttgtttggtc
    14041 agtatggcct aagcgatctt tcaagacttc ccagctacag tgttccgcta ctaagcttgc
    14101 cattgtatga cgagctaaat gagtatgaaa tggcttatta attcctgagc gattcacgca
    14161 ccgtttgacg tgatcattta catactctcg acgataagga acaccacgtt tactagaatc
    14221 aagatacaca aacaaatatg tttcttctat aataaacctg taatgttgcc tcatctcacc
    14281 caaagcctta atcaactgtt gtagcttttc cataactaga ggagttacta gaactcgtct
    14341 agcagaacta actgtcttag tagtttcaat tcgaaaatcc ttactcttac ctttaactgc
    14401 cgtttgctta tagaacagaa tttcatttct tttgaaatct atatctccag gctgtagagc
    14461 aagcgcctcg ctgactcggc agccagtgta aaatagaaca tggaaaagta cagacatcgg
    14521 taattcctca tgaacaatgc cataattcaa aaaagttctc aattcatcga cagtaagaaa
    14581 cttgtcctca atattattta tggcttcttt taaatcagtt accgttaact gatattttgg
    14641 cattctcaca gacttcattg gattttcact tatcaaattc tttctttgac aatatttaaa
    14701 aatcatattt agaacttgaa taagtgattg taaactattt ttggcatagc caacatttgt
    14761 tccattaacg ccacattcct ttaaggtaaa aagcaattct tgaaggcact ctggtgtcaa
    14821 atcagacaac tttttatcac caatccatcg aacaataatt tttaattgtt cctctcgctt
    14881 atcataggtt atttcctttt gttcatttaa cgaacggtaa tattggaacc attgctcacc
    14941 tacaacacta aacttgtcat tgcttgcaac aatttttttc ttaagccttt gttgtttctc
    15001 catttccaga taagcgagtt gcgcctcacg ttttgaatta aagccacgtc ttgttgttcg
    15061 atatgcttga aagtaccatg tgatcctacc agtagaactg atttgcttct tgaatcgatc
    15121 tgttttttcc atttattgat tcctcctatt ttgaaggaac ccaacaagca gaaacccttt
    15181 ggaaatcttt ctatctatgt catcattgta ccgcatctta gaaagaaaat gtaacttata
    15241 aagatcgaag tagtcgcaat ttttctcgat agtcattcga atcactcttt ctcatccatt
    15301 ctaaaacatc atcacgaaaa tagtgtcctc gaatcccgta ccaacaggga ggaaactcac
    15361 caagttttac taaacggttc agtgtactat cacttatctg aaatagtcgc tttaaatcag
    15421 tatttgttaa taccagaggt aaatgactga ctgcaagcaa tttttccgtg taatcttcca
    15481 gttttttttg taaaattgaa tagaactcta tttccagaga attaacattt gttttaactt
    15541 ccaactccat cacccttctc tctcaaaatc aaaacgacca ccacggtacc ccttaaaatt
    15601 gtaaaaaaac actccagtac tccatcaaaa cggactagaa aagaggaatt tttaatatga
    15661 aacaaggaat tgcagacata aaaataatta aagaaattct tgaaaaatct acggctaatg
    15721 caatagcatt cggaacagga atcaacttga gtacagtaaa aaaacttaaa agtggagaga
    15781 gagctgaaga aaaattaaat cttgccgatg ctattaaaat cacagaattt ggcatgaaaa
    15841 atatgccaac caaaatcgaa atatggaaat agtagttttt ctgatctatc agctgttttg
    15901 ccaaagcaca taggaatctc acctcccccc agtaatggcg ggccgatttg gttacggaag
    15961 tatcattatc gtagtcgcga ttctcatatt aaaatttgtc gcttaaaagc taaccttgtc
    16021 atggcgtaac tagagaatca aaatctacat gtactgatag atttgctatt catttgtcaa
    16081 agagcgctag gctattttca gcctatggaa atcctttatt ttgacccgat aaaaaacttc
    16141 catagaatga aaaggaaagg gaaaaaatac tttaacgagt tgtatcaaat tcaagtatct
    16201 tctcaatcaa ttttgtttcc agttgtctac gcatatattc atctacatac ataaccattc
    16261 ctttttcttc ttcataaact ggtttcatgg ctaaccgtga aatataattt tgatattttg
    16321 acagaacgat ggacatggca attgaatcac cagaagctgc ggctttgatt gtcgttagtg
    16381 gtatgaatgg tatatatcgt ttattttgct tcatatttga cacccaaata ctttcctagc
    16441 tcttccaaag ccatttgtcg ttggtaccaa acactgccga gacttttccc aataatatcg
    16501 ccaatttcac gatcattaag accgatgagg aaggacataa aaatgatttc ttgtctttga
    16561 ctaggtaatg ctgcaatcgc atttgccaac tcctcattgg aaataaagat tttcatacca
    16621 aggacaataa aagtaccact actattcaaa tttggttcca aataatagaa ctctgtacct
    16681 aacccttttt gttccaatat ttccattgat atttgccgtt ggcgaaatct agcgtacttc
    16741 ttttgaatat ttaacgcctc attgcagact actttcttac aaaaactgtc aaacgtatgt
    16801 tgaatgtggg tttcctctga gtcgcccata atattctccc cctcaaaaaa ttcattcaac
    16861 tcgttttact tctatccctt tccattatta ctacaatcta gga
//
LOCUS       DAFBVQ010000056        16509 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.059, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000056 DAFBVQ010000000
VERSION     DAFBVQ010000056.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.059"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            184..1182
                     /locus_tag="LLC22_002127"
     CDS             184..1182
                     /locus_tag="LLC22_002127"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296073.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5435384.1"
                     /translation="MEIYDITIIGAGPVGMFAAFYAGMRQAKTKIIDSLPQLGGQLAT
                     LYPEKYIYDIPGYPAIKASELIDQLEKQLTTFNHTFHLKEEVLSLTREDEVIEITTNK
                     GIHYSKAVILALGNGSFQPRKLNLDNAESFENHGLDYFVNDLMKYAGKKVAIAGGGDS
                     AIDWTLMLEPIASEVYLIHRRPEFRAHEHSVSRLKSSSVNLLTPYLIDGLSGNNGELT
                     DIRLKKVKSDETIDLMIDSLIVNYGFSSNLEHLSSWGLDSTRNAITVKSDMSTSIPGV
                     YAAGDICTYEGKVKLIATGLGEAPTAVNNALHYINPKERTQPGHSTSLYDKNLRPS"
     gene            1294..1803
                     /locus_tag="LLC22_002128"
     CDS             1294..1803
                     /locus_tag="LLC22_002128"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287163.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidylglycerophosphatase A"
                     /protein_id="HBK5435385.1"
                     /translation="MVVKTETLEEKARELLKERGVTVEDIAQLVMFLQKDYISDLTLA
                     DCTESVNSVLTKREVHNAIITGIQLDILAEKKKLMSPLQHIIEDDEGLYGIDEILALS
                     IVNVYGTIGFTNYGYIDKVKPGILKELNSHDGVHVHTFLDDIVGAIAAAAASRLAHKE
                     PEKRSRLTQ"
     gene            complement(1833..2492)
                     /locus_tag="LLC22_002129"
     CDS             complement(1833..2492)
                     /locus_tag="LLC22_002129"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01906 family membrane protein"
                     /protein_id="HBK5435386.1"
                     /translation="MKNSRWQWMEYAGLFSLFLTLISLAVGVTINFRPLYVFDIGHLQ
                     ILDYTSLDQETLLKNFDHLMNYLNNPFKTILSLPDFPVSASGAHHFYEVKILFLVDYA
                     VFFITLIPSILFIKYLQKNDRLWRLIRPFQIGMLLPVVFGFFMMIGFDRFFILFHETF
                     FNNDDWLFDPVTDPIINVLPEEFFMHSFILFFVLLELFFAVFLFLGKNSLKQTKKKEL
                     V"
     gene            complement(2494..3258)
                     /locus_tag="LLC22_002130"
     CDS             complement(2494..3258)
                     /locus_tag="LLC22_002130"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307277.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TIGR01457 family HAD-type hydrolase"
                     /protein_id="HBK5435387.1"
                     /translation="MDYKGYLIDLDGTIYRGTQPIPAGKRFVEELQKRKLPFLFVTNN
                     TTKSPETVANRLADEFDIHVAPETVYTATLATIDFMKADGKGKKVYVIGEAGLIDLIL
                     AAGFTWEEEAPDYVVVGLDNYLTYEKVVKATLAIQKGATFIGTNPDKNIPTERGLLPG
                     AGSVISFVETATQTPPIYIGKPEAIIMDKAVEVLGLQKEEVIMVGDNYETDIQAGIRN
                     NIDTLLVLSGFTKEEDVPGLPIPATYVKQSLDEWSF"
     gene            complement(3266..3943)
                     /locus_tag="LLC22_002131"
     CDS             complement(3266..3943)
                     /locus_tag="LLC22_002131"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287156.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YutD family protein"
                     /protein_id="HBK5435388.1"
                     /translation="MSAKQNEQQNVEHKTEIAKKKSSAEQETTVTEELTAALEEIVEE
                     PKAEKVKGELVTLLDDSNFLIGERHYRLVSDYREGFNAEKLGERYSDVLARYDYIVGD
                     WGYEQLRLKGFFQADNRRAHPDQRIDSLEDYLYEYCNFGCAYFVIERIGGKKEKTTQR
                     RKKKKNHNRAYIDEKKGPVASNRKKPVIKNRKTESAKTSEKVKKQEQPKQVEKTKTAF
                     TIRKREE"
     gene            complement(3980..5365)
                     /locus_tag="LLC22_002132"
     CDS             complement(3980..5365)
                     /locus_tag="LLC22_002132"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metallophosphoesterase"
                     /protein_id="HBK5435389.1"
                     /translation="MEKIVILHTNDLHSHLENWPRIRRFLDQRKRENEKKEKTTTIAV
                     DLGDFVDRWHPLSEATNGQENILLMNEVGYDAATIGNNEGVGNSKEELNHLYDHAEFD
                     IILDNLFDKNTLQPPAWTKPYKIITTKHQTKIGLIAFTAPFPLTYNPNGWDIRNPYDI
                     LPELVEDLRSQVDVLVLMSHLGIQDDFQIAKEIPAIDVILGSHTHHLFREGHVINDVQ
                     IAAAGKYGQYVGEVHLTIDEEKKILKHSAKAIPTETMTAFTEDEQEINSYLERGHELL
                     KEKEVADLPFSLSLDIFNEHSFIQVAFEAVKERGKTEAAILNSGLFLTEIPKGRVNQD
                     QLHTALPHPMHLLNVTLGGNDLIRLVLEIEKNRNFLRNYPMKGMGFRGKIFGQMVYNG
                     ITYDSINHQVFWKNKPIDLNKNYTFTTVDHLMFVPFFPTIEIAGKNEFLFPEFIRSVV
                     GDYLKAHYPIK"
     gene            complement(5575..5659)
                     /gene="ffs"
                     /locus_tag="LLC22_002133"
     ncRNA           complement(5575..5659)
                     /ncRNA_class="SRP_RNA"
                     /gene="ffs"
                     /locus_tag="LLC22_002133"
                     /product="signal recognition particle sRNA small type"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00169"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00169"
     gene            complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="LLC22_002134"
     CDS             complement(5682..6197)
                     /gene="tadA"
                     /locus_tag="LLC22_002134"
                     /EC_number="3.5.4.33"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA adenosine(34) deaminase TadA"
                     /protein_id="HBK5435390.1"
                     /translation="MVNTNLDAVEKEKWMRLALAEAKKAEMLHEVPIGAVVVLDGKVI
                     GRGYNLRETTQDATTHAEMLAIKEACEKVGSWRLEDAALFVTLEPCPMCSGAMILSRV
                     AEVYFGAYDPKGGTAGTLMNLLEDERFNHQAYVEGGILEDECGMILTDFFRKLRQRKK
                     KLKKDWSTNEK"
     gene            6304..7161
                     /locus_tag="LLC22_002135"
     CDS             6304..7161
                     /locus_tag="LLC22_002135"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435391.1"
                     /translation="MKMDKLLALYPQAQKKNSPASEADILSFAIDDAFIWIKQDSLSQ
                     QETSLLKALFPVINDQKKHPWYHYLFKDASCVQEKSFRLIQLHVESKGEFLKKEWQDT
                     ILELFRYSADFFFYTDTDALLVEQINRDYLDATEINGIFLSLDADFDTTTSVFVGSFH
                     SPGTDLVPLFAEERKIFLTEQNNLYTHSRTFSMQDVALHYYTKDTVKDSKLIKSYIEL
                     IKQNEMEVIIQELWNELGNVSSAAKTLFLHRNTLKYRIEKFQEQSGFNLKKANDLLFC
                     YLLLLHEHN"
     gene            complement(7242..7577)
                     /locus_tag="LLC22_002136"
     CDS             complement(7242..7577)
                     /locus_tag="LLC22_002136"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435392.1"
                     /translation="MKTSTKVTIGLSVAAAASVATAVVVSGKVMEKIHHMTTRTKVKK
                     FVYDKFDGNEKLLEIVDGLSDSDLDSLMGMLAKIKSGKKKISVYGDSIKDSTEDVKDR
                     LMHFVEKMM"
     gene            complement(7644..9014)
                     /locus_tag="LLC22_002137"
     CDS             complement(7644..9014)
                     /locus_tag="LLC22_002137"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334069.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RsmB/NOP family class I SAM-dependent RNA
                     methyltransferase"
                     /protein_id="HBK5435393.1"
                     /translation="MKEEATTLPQQFIKKYRLLLGEEASDFFSALEQGSVKKGFRWNP
                     LKPAGLDMVQTYHSEELQPAPYSNEGFLGTVNGKSFLHQAGYEYSQEPSAMIVGTAAA
                     AKPGEKVLDLCAAPGGKSTQLAAQMKGKGLLVTNEIFPKRAKILSENIERWGVSNAIV
                     TNHAPAELVPHFSGFFDRIVVDAPCSGEGMFRKDPNAIKEWTEESPLYCQKRQQEILS
                     SAIKMLKNKGQLIYSTCTFAPEENEEIISWLVENYPVTIEEIPLTQSVSSGRSEWGSV
                     AGLEKTIRIWPHKDQGEGHFVAKLTFHGQNQMHKEKKTRKKSKVQMTKEQEKLWTEFS
                     NDFHYEATGRLLVFNDHLWEVPELAPSLDGLKVVRTGLHLGDFKKNRFEPSYALALAT
                     KKIENIPCLPITQKEWQSYTAGETFQRDGNQGWVLLVLDKIPVGFGKQVKGTVKNFFP
                     KGLRFH"
     gene            complement(9092..9628)
                     /locus_tag="LLC22_002138"
     CDS             complement(9092..9628)
                     /locus_tag="LLC22_002138"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300636.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5435394.1"
                     /translation="MMGRVTNYSKEYLLFKSMVYVEEYGMKSITARELAEFCGCSTYP
                     IYTHFKSISGLKEKILEEITVYFENYLAECSSDDVLSIVYLLKDFFSIHESIREIIAK
                     SDLDMDSLFKRPFFSYVKGHTKIKEEKSLELVWLNALGSLRSDDSSQDFLEMMNAVWD
                     KNEVTDEYLENILKEQSP"
     gene            9937..11418
                     /locus_tag="LLC22_002139"
     CDS             9937..11418
                     /locus_tag="LLC22_002139"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298955.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435395.1"
                     /translation="MLIEARKKELLVLQMVIQKNNCSLQELSNDLHIPKRTIKELIRK
                     INVSLKQFLLIDEFIYSNHKGEIQTKETDQTKKLAVFSKLKLCYLKESNRFNYLMLLI
                     NYPQTAVPKKYLLEQLYISPSYLEKLTKQLNHSLKKFHLRILSVKNCCTLEGNELSIR
                     LYLYFFLSDTFGGNDWPFSSLELNALKMNSTDEQIEKISKQEKNIYLLLTLFILRNKQ
                     QAYFPKTSSEITELMDLLQHTHDYSEYFTSFSVSRPCEETETERAYFNYFFYCFFPNQ
                     ISFRQKQEIGFLFSTSKNLICRQVGQLMTYLTQQFPLNHLENKIPIYFYFLVLAVVFF
                     ELLGESSSSFSTLCFPEATSNHSSSFIQEKKLREKIDTIFSKNGERNQISQYLSQLIQ
                     HLLQTETKEQLLIHLQITKQFTGNYHLQSHLQQLFRKDAVKITAYSEHADLIITDQHE
                     KISDETETFYLDTTHNTVLFGKLIKAVHELYMKKGYENKTKRM"
     gene            complement(11521..12228)
                     /locus_tag="LLC22_002140"
     CDS             complement(11521..12228)
                     /locus_tag="LLC22_002140"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853426.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc metallopeptidase"
                     /protein_id="HBK5435396.1"
                     /translation="MYGYGMYGFLDPTFLLVILGLVISGIASAYVNSTFRKYDQVRSK
                     NNVTGTQAAQYILQSQQINNVGVQQIAGDLTDNYNSGNKMLSLSQATAQSTSVAAIGV
                     AAHECGHAVQDASGYVPLKIRAALVPAANFGSMISFPLIMVGVLLSWNSTLINIGIFA
                     FSLALLFQLVTLPVEFNASRRAIQILSEGGLLTEEEVPMARHVLFAAALTYVAAALST
                     FLQLLRLILLFGGNRRD"
     gene            complement(12307..12645)
                     /locus_tag="LLC22_002141"
     CDS             complement(12307..12645)
                     /locus_tag="LLC22_002141"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkylphosphonate utilization protein"
                     /protein_id="HBK5435397.1"
                     /translation="MTLPNCPECGSEYTYEDRGLLICPECGNEWNKEEQETVIEDGLV
                     VLDANGNRLLEGDSVTVIKDLKVKGASGAIKQGTKVKNIRLVEGDHNIDCKVEGFGPM
                     KLKSEFVKKN"
     gene            complement(12756..13718)
                     /locus_tag="LLC22_002142"
     CDS             complement(12756..13718)
                     /locus_tag="LLC22_002142"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional oligoribonuclease/PAP phosphatase
                     NrnA"
                     /protein_id="HBK5435398.1"
                     /translation="MTVQQEIVDTIKKYDKIIIHRHLRPDPDALGSQVGLAELLRESF
                     PEKEIRQVGETIEGLRFLAEMQEVEDVFYQGALVIVTDTANSPRISDQRYQLAEKLIK
                     IDHHPNDDPYGDLVWVNTKASSCSEMIAEFALMFPESLKMNVKAARLLYAGIVGDTGR
                     FLYPSTTSRTLEIASILRNYPFDASALNREIEQMPMKVAKLSGYLYQNIQVDENGAGR
                     IILPQEILDKYGIDDSETASIVSLPGVIDEVLAWGIFVQQPSGYYRVRLRSKGPIINE
                     LAKRHHGGGHPLVSGANAKDLAEVEEIYKEIQDICQSYKSRKTE"
     gene            complement(13733..15064)
                     /locus_tag="LLC22_002143"
     CDS             complement(13733..15064)
                     /locus_tag="LLC22_002143"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CBS domain-containing protein"
                     /protein_id="HBK5435399.1"
                     /translation="MATKHDLILEYIESLPVGNRISVRSIAKELNVSEGTAYRAIKDA
                     ENVGLVSTIQRVGTIRIERKLKKHIERLTFGEVVRIIEGDVLGGAAGLDKVLNKFVIG
                     AMTKHAMERYITPGSLMIVGNRAEVQKLALEDGAAVLITGGFNTTAEIAKLADDLEMP
                     ILRTSYDTFTVATMINRALSDQLIKKDIMLVSDIYMPAEKTHYLQQTDTISDYQRLSE
                     ETQHSRFPVVNRHHRLMGIVTAKDVLGKSPNQIIDRVMTKEPISVKKTMSIASVSHQM
                     IWDGLEVMPVVSDDLTLEGLITRQDVMKAMQLVQRQPQIADTISDQISGNIHTIDTDR
                     EGNRLENPKFKFVVAPQMVNGVGTISFGVLSEIISDVAQKTMVMNQKRNILIEQVNLH
                     YLRLIQLESELDIRPRVLEIGRRSAKLDIEVFIENTIVSKAIVVCQVMERS"
     gene            complement(15072..15752)
                     /locus_tag="LLC22_002144"
     CDS             complement(15072..15752)
                     /locus_tag="LLC22_002144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="metal-dependent hydrolase"
                     /protein_id="HBK5435400.1"
                     /translation="MKITYHGHSCLTIEMENGQRVMIDPFITGNPLTDLTAEEVKTDW
                     LLITHGHSDHIGDMIPIAKENQATIISIVEIADYANSRGVDSFGMNIGGKHAFPFGVV
                     KFVHAQHSSSYEVDGIVQYMGEPSGIIIQAEGKTIYHAGDTAYFSDLGLLAEEFDIDV
                     AFLPIGDNYTMGPEDAAKAAQTIRAKKVVPIHYNTFPVIEQDPESFVELLEDSEGKIM
                     SVSETLEV"
     gene            complement(15971..16450)
                     /locus_tag="LLC22_002145"
     CDS             complement(15971..16450)
                     /locus_tag="LLC22_002145"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoacyl-tRNA deacylase"
                     /protein_id="HBK5435401.1"
                     /translation="MMSQTKVERYLEEQKISYQPLDFSHVVEESFTEELQKRGIDPAL
                     ICKTLVVKGNKTGVIIALIPLNDHLDYKKTRQVTKDRKVGFPGMDFVLMHTGYPHGAN
                     TPIGIKLAHPDYCFLADSSLKEKEEVIVSSGEIGRSLRIKVADLEKIVHPIYADLIS"
BASE COUNT         4885 a         3441 c         2736 g         5447 t
ORIGIN      
        1 tttgcatact tcataataat aataacataa tacctaacct ctcgtaaaaa tactagattt
       61 gttttctttt atttttcatc actagataca ttctataact taccgtttcg atttcgaatt
      121 caaacatttt tgagaagcat tctcaattaa attctgctat agtgtgaaaa gggaggaatt
      181 tttatggaaa tctatgacat tacaatcatc ggtgcaggtc ctgtagggat gtttgccgct
      241 ttttacgcag gaatgcgcca agctaaaaca aaaatcattg acagtctacc tcaacttggt
      301 ggtcaattag caactttgta tcccgaaaaa tatatttacg atattcctgg gtatccagca
      361 ataaaagcaa gtgaattaat cgatcaatta gaaaaacaat taactacttt taaccataca
      421 ttccatttaa aagaagaagt tctctcgctt actcgtgaag acgaagttat cgagattact
      481 acaaataaag gcatccatta ttccaaagca gtcattttag ctttaggaaa tggttcattc
      541 cagccaagaa aattgaattt agataatgct gaatcatttg aaaaccacgg attggattat
      601 ttcgtgaatg atttgatgaa gtatgctgga aaaaaagtcg ctattgctgg aggtggtgat
      661 tctgctatcg attggacgtt gatgttagag cctattgcaa gcgaagttta cttgattcat
      721 cgtcgcccgg aatttcgtgc gcacgaacat agtgtatcac gcttgaaatc ttcatctgtc
      781 aacttgctta ctccctatct catcgatgga ttatcaggca ataatgggga actgacagat
      841 atccggttaa aaaaagtgaa aagtgacgag acgattgatt tgatgattga ttctctgatc
      901 gtcaattatg gattctcttc taatttagaa catctttctt cttggggact tgatagtacc
      961 agaaatgcca ttactgtaaa atcagatatg tctacttcta ttccaggcgt ttatgcagct
     1021 ggtgacatct gtacctatga aggaaaagtg aaactgattg ctactgggct cggtgaagca
     1081 cctactgcag tgaacaacgc tttacactat attaatccaa aggaacgaac tcagcctggt
     1141 cacagcacaa gcttatacga taaaaatctt cgtcctagtt gattttttat atctctttgc
     1201 atttcaagtt aaacccgaaa gcagtttctt gcattttttt catgttccgt taacatgaaa
     1261 tagagaaaga aaaaataaag ggggagcaat aatatggtcg tcaaaactga gactttagaa
     1321 gaaaaggcaa gagaactatt gaaggaacgt ggcgtaactg tagaagatat cgcacaactt
     1381 gtcatgtttt tacaaaaaga ctatatttct gatttgactt tggcggattg tactgaaagt
     1441 gtcaacagcg tgctaacaaa gcgtgaagta cataacgcca ttatcactgg aatccaatta
     1501 gatatattag cagaaaagaa aaaattgatg agtccgttgc aacatattat cgaagatgac
     1561 gaaggccttt acggtatcga tgagatccta gccttgtcaa tcgtgaatgt ttacggtacg
     1621 atcggcttta cgaattatgg ttatatcgac aaggtgaaac ctggtatttt aaaagaacta
     1681 aacagccacg atggcgttca tgtccatacc ttcttagatg atatcgtcgg agcgatcgcc
     1741 gctgctgctg ccagtcgatt agcacacaaa gaaccagaaa aaagaagtcg ccttactcaa
     1801 taattcaaca aaaaaagaaa gaaaacgtct atttagacga gttctttctt ttttgtttgt
     1861 ttcaagctat tttttcctaa gaaaagaaaa acagcaaaaa ataattctaa taatacaaaa
     1921 aataagataa agctatgcat gaaaaattct tctggaagta cattgatgat tggatcagta
     1981 acgggatcga ataaccagtc atcgttgttg aaaaacgttt catgaaaaag gataaaaaag
     2041 cgatcaaatc ctatcatcat gaaaaaaccg aaaacaactg gcagtaacat gccgatttga
     2101 aacggacgaa tcaaccgcca aagccgatca ttcttttgca aatatttgat aaacaaaata
     2161 ctcgggatca aagtgatgaa aaacacagca taatccacta aaaacaaaat tttcacttca
     2221 taaaagtgat gggctccgct agcagaaact gggaaatctg gcaagctgag gatggttttg
     2281 aagggattat tgagataatt cattaggtga tcaaaatttt tcagtaacgt ctcttgatct
     2341 aaagaagtat aatccaaaat ttgcaaatgt ccgatatcaa atacgtatag tggtcgaaag
     2401 ttgatcgtca caccaactgc cagactgatc agtgtcagaa ataggctgaa caatccagca
     2461 tattccatcc actgccatct cgaatttttc atattagaag ctccattcat ccagtgattg
     2521 tttcacatag gtagctggga taggcaaccc aggtacatct tcttcttttg taaaacctga
     2581 taaaacgagc aaagtatcta tattattgcg tatcccagct tggatatctg tttcatagtt
     2641 atctccaacc atgattactt cttctttttg cagccctaat acttcaacgg ctttatccat
     2701 aatgatggct tctggttttc cgatgtagat cggcggcgtt tgggttgctg tctctacaaa
     2761 agagatgact gaccctgctc caggaagaag gccgcgttca gtaggtatat tcttatctgg
     2821 gttcgttcca atgaaagtag cacctttttg aatagcaagt gttgctttaa ctactttttc
     2881 ataggtcaga taattatcta agcctaccac tacatagtca ggagcctctt cttcccatgt
     2941 aaatccggca gctaaaatca agtcaatcaa tcctgcttct ccgataacat agactttttt
     3001 cccttttcca tctgctttca taaaatcgat tgttgccaaa gtagctgtgt agactgtctc
     3061 tggagctaca tgaatgtcaa actcatctgc tagacgatta gctactgttt ctggtgactt
     3121 agtcgtgtta ttggtaacaa acaagaaagg taattttctt ttttgcaatt cttccacaaa
     3181 tcgtttaccg gccggtatgg gttgtgtccc acgataaatc gttccgtcta aatcaattaa
     3241 atatccttta tagtccattc atccactact cttccctttt tctgatcgta aatgctgttt
     3301 ttgttttttc tacttgttta ggttgttctt gtttttttac tttttcagag gtttttgctg
     3361 actctgtttt tcgattttta ataaccggtt ttttgcgatt agatgcgact ggtccttttt
     3421 tctcatcgat atacgcacga ttatggtttt ttttcttttt tcggcgctga gttgtctttt
     3481 cttttttacc gccgattctc tcgatgacaa aatacgcaca accaaaattg caatattcgt
     3541 aaagatagtc ttccaaggaa tcgattcgct gatctggatg cgcccgtcga ttatccgctt
     3601 ggaaaaatcc ttttaggcgt agttgttcat aaccccaatc tcctacgata taatcatatc
     3661 gggctagtac atcactgtaa cgttctccaa gcttttctgc attaaatcct tcacgataat
     3721 cggacacaag ccgataatgt ctttcaccta tcaaaaaatt actgtcatct aacagtgtca
     3781 ctagctcgcc tttgactttt tctgctttag gctcctcaac gatttcttcc aaagcagctg
     3841 tcagttcttc ggtgactgtt gtttcctgtt cagctgatga ttttttctta gcaatttctg
     3901 ttttatgctc aacgttctgc tgttcatttt gttttgcaga catgcgttca ccacctatct
     3961 tttttattat accttgtttt tatttgattg ggtagtgagc tttcaagtaa tctcctacca
     4021 cacttcggat aaattcaggg aacaaaaatt cattttttcc agcaatctca atcgttggaa
     4081 aaaatggaac aaacatcaaa tgatctacgg tagtaaaagt ataattttta ttcagatcga
     4141 ttggcttgtt cttccaaaag acttgatggt taatagaatc atatgtgatt ccattataga
     4201 ccatctgccc aaaaatctta ccgcgaaatc ccattccctt cataggatag ttacgtaaaa
     4261 agttacgatt tttttctatt tctaaaacta agcggatcag atcatttcca cccaatgtga
     4321 catttaacaa gtgcatcgga tgcggcaacg cagtgtgaag ctgatcctga ttgacccgcc
     4381 cttttggaat ttcagttaaa aacagaccac tgtttaatat tgctgcttcc gtctttcctc
     4441 gttctttcac cgcctcaaag gctacttgga taaacgaatg ctcattgaag atatctagac
     4501 tcagagaaaa tggcaaatct gctacttctt tttcttttaa taattcatgc ccacgttcta
     4561 gataactatt tatttcttgt tcatcttctg taaaagctgt cattgtttcg gtagggatgg
     4621 ctttggctga atgcttaagg atttttttct cttcatcgat ggttaaatgg acttcaccga
     4681 catactgccc gtactttcca gcggctgcta tttggacatc attgattacg tgaccttctc
     4741 tgaataaatg atgggtgtgc gatcctaaaa taacatcaat tgctggtatt tcttttgcaa
     4801 tttggaaatc atcctgaatc ccgagatgac tcatcaaaac taaaacatcc acttgtgaac
     4861 gtaaatcttc gactaattct ggcaaaatat cataaggatt ccgtatgtcc cagccattcg
     4921 gattataagt aagcggaaat ggagcagtaa atgcaattag tccgattttc gtctggtgtt
     4981 tcgttgtaat gattttatat ggtttcgtcc atgccggtgg ctggagcgta tttttatcga
     5041 ataagttatc caggatgata tcaaactcag catgatcgta taaatgattc aactcttctt
     5101 tggaatttcc tacgccttca ttgtttccta tcgtcgctgc atcataacca acttcattca
     5161 tcagcaagat attttcctgt ccattcgttg cttctgacaa tggatgccaa cgatccacaa
     5221 aatcacctag atctactgca atcgttgtcg ttttttcttt cttttcgttt tctcgtttac
     5281 gttgatccaa aaaccttctg atccttggcc aattttctaa atgagaatgc agatcattcg
     5341 tatgtaaaat cactattttt tccatgtacc ctctcgcctc tctttatctt tatcatacca
     5401 taggcagctt tttcttccat tgaaacaagc tctatttcag agtttttcct gccttgaagc
     5461 aaattgtata agtacaatat tcgataaatc agtctggcta aaaaatcagg aacattcatt
     5521 tttacagtac tataaaaata aaaaaaacag acccgaaagt ctgttgtcgt ttcattataa
     5581 tcagacacat ggcggaacct gcttagtgct gcttccttcc agacctgaca cgcttcacaa
     5641 gcccaccatt gtcctagcct ttcggcaaag aatagtatac cttatttttc attcgttgac
     5701 cagtcttttt ttaatttctt ttttcgctgg cggagctttc ggaaaaagtc agtcaaaatc
     5761 atcccacatt cgtcttctaa aatgccacct tctacatatg cttggtggtt aaaccgctcg
     5821 tcctccaaaa gattcatcaa ggtaccggct gttccgcctt ttggatcata cgcgccgaaa
     5881 taaacttctg ctacacgaga caaaatcatc gcgccgctgc acataggaca aggctctaag
     5941 gtaacaaaaa gtgcagcatc ttccaagcgc cagcttccca ctttttcaca ggcttccttg
     6001 attgcaagca tttctgcatg tgtagtagca tcttgcgtgg tttctctaag gttatatcct
     6061 cttccaatca cttttccatc caatacaacc actgctccaa tcggaacttc atgaagcatt
     6121 tctgctttct ttgcttctgc caatgcaagg cgcatccatt tttctttttc tactgcatca
     6181 agatttgtat ttaccaatta cccttccctg cctttgtttt ttcttgtttt actttagcat
     6241 atgataaaaa ggctgtaact aacttttttt tctatggtaa aataaataca agaggtgaac
     6301 aagatgaaaa tggataaatt acttgctctt tacccacaag cacagaaaaa aaactctcca
     6361 gcatcagaag cggatatcct ttcttttgca attgatgatg cttttatctg gatcaaacaa
     6421 gattcattat ctcaacaaga aaccagcctt ttgaaagcgt tattccctgt aatcaacgat
     6481 caaaaaaaac acccatggta tcactatctt tttaaagatg cttcttgtgt tcaagaaaaa
     6541 agctttcgtt tgatccagct tcacgtcgaa tcaaaaggag aattcttaaa aaaagaatgg
     6601 caagatacta ttttggaatt atttcgctat tctgctgatt tcttttttta tacagacaca
     6661 gatgcgctct tagtcgaaca aataaaccgt gattatcttg atgctactga aatcaacggt
     6721 atttttctat ctttagatgc tgattttgat acgacaacgt ctgtattcgt tggttctttc
     6781 cattcacctg gcaccgacct cgtccctttg tttgctgaag aaagaaaaat ttttttaaca
     6841 gagcaaaaca atctttatac tcacagccgt actttttcta tgcaagatgt ggctttacat
     6901 tactatacaa aagatactgt aaaagatagt aagttgatca aaagttacat agaactgatc
     6961 aaacaaaatg aaatggaagt gatcattcaa gaattatgga atgaattagg caatgtcagc
     7021 tctgctgcaa aaacactgtt tcttcatcgt aatactctaa aatatcgaat cgaaaaattt
     7081 caagaacagt ctggtttcaa tctaaaaaaa gccaacgatt tactgttttg ctatctttta
     7141 ttgcttcatg aacataatta aagatagatt aaaggggttg tgacaataat tttgtcacaa
     7201 ccccttattt cgaatgaata gtgttcaaaa gctagtttct cttacatcat tttttcaaca
     7261 aaatgcatta gccggtcttt tacatcttcg gttgaatctt tgattgaatc accataaaca
     7321 gagattttct tttttcctga tttgattttt gctaacattc ccatcaaaga atccaagtca
     7381 ctatctgaaa gaccatctac gatttctagt aatttttcat ttccatcaaa tttgtcatag
     7441 acgaattttt ttactttcgt ccgagtagtc atatgatgga tcttttccat tacttttccc
     7501 gatacaacga ctgctgtcgc tacactggca gcggctgcta cgcttaatcc gattgttact
     7561 tttgttgatg ttttcataag tatcagctcc tttttatcta tctccatcat agcatagaca
     7621 aaaaaataaa cgaactaatc cactcagtga aatctcaatc ctttagggaa aaagttcttt
     7681 actgttcctt ttacttgttt cccaaatccg acaggtatct tatctaatac tagcaaaacc
     7741 catccttgat tcccatcacg ttgaaatgtt tctcctgctg tgtaagattg ccattccttt
     7801 tgagtgatcg gcaagcaagg tatattctct atcttttttg tagcaagcgc taatgcatag
     7861 ctaggttcaa atcgattctt tttgaaatct cctaaatgca aacctgtacg tacgactttt
     7921 aaaccatcga gagaaggggc taactcagga acttcccaaa gatggtcgtt gaacactaaa
     7981 agtcttccag tagcttcata atgaaaatca tttgaaaact ccgtccagag tttttcctgc
     8041 tcttttgtca tttgcacttt actttttttt cgtgtcttct tttctttatg catctgattt
     8101 tgtccatgaa aagtcagctt tgcaacaaaa tgtccttcac cctgatcttt atgaggccat
     8161 atacgtattg ttttttccaa accagctacg cttccccatt cagaacgtcc tgaactaacg
     8221 gattgagtca aaggaatctc ctcaatcgtt actggataat tttctacaag ccagctaatg
     8281 atctcttcat tttcttctgg tgcaaacgta caagtcgaat aaatcagttg tcctttattt
     8341 tttagcattt ttattgctga agacaaaatc tcttgctgac gtttttgaca gtatagcgga
     8401 gattcttctg tccactcttt tattgcattt ggatcttttc ggaacattcc ttctcctgaa
     8461 caaggagcat caaccacgat ccgatcaaaa aagcccgaaa aatgagggac aagttctgcg
     8521 ggtgcatgat ttgtcactat tgcgttcgaa actccccatc gttctatatt ttctgataaa
     8581 atcttcgcac gtttcggaaa gatctcattc gtcactaata accctttccc cttcatttga
     8641 gcagctaatt gggttgattt accaccggga gccgcacaca aatccaaaac tttttcaccg
     8701 ggttttgctg cagcagctgt tccaacgatc attgcacttg gttcttggct atattcatac
     8761 ccagcttgat ggaggaaaga ctttccattg acagtgccaa gaaatccctc attgctgtag
     8821 ggagcgggtt gtaattcttc gctatggtaa gtttggacca tgtccaatcc tgccggtttt
     8881 agtggattcc accgaaatcc ttttttcacg cttccttgtt caagcgcaga aaaaaaatcg
     8941 gatgcttctt cgcctaaaag aagacgatat tttttgataa attgctgtgg taacgttgtc
     9001 gcttcctcct tcattccaat gtttcgttag acattttaca atctttttta cgaaaaataa
     9061 aggtggctga tctacttttt catgttgctg cctaaggtga ctgttccttt aagatatttt
     9121 ccaagtattc atccgtcacc tcgtttttat cccaaacagc gttcatcatt tcaagaaaat
     9181 cttgagaaga atcatctgag cgcaaacttc ccaatgcatt aagccatacc aattcaagcg
     9241 acttttcttc tttgatcttc gtgtgacctt tgacatatga gaaaaatggc cgcttaaata
     9301 gcgaatccat gtctaaatca gattttgcaa tgatttcacg aatactttca tggatagaaa
     9361 aaaaatcttt caataagtag acaatgctta aaacatcatc ggaactgcat tcagctaagt
     9421 agttttcaaa ataaacagtg atttcttcta atatcttctc ttttaacccg ctgattgatt
     9481 tgaaatgtgt ataaatcggg tatgtagaac aaccgcagaa ctctgctaac tctcttgcag
     9541 taattgactt cattccatat tcttccacgt ataccatact tttgaacagc aaatattctt
     9601 tactataatt tgttactctc cccatcattc ttacctccgt ctcttttcat ctacccataa
     9661 ataaataaca taaataattc taaaaatatt attgataatt atcaaaacat atttagttat
     9721 atccattaaa aatcaatttt tccgccttaa aaacaagaat atcttgacaa aataccctag
     9781 gaaataaaca atagaataaa caaggtaaca aaaaaattaa ataacgttat ataaaaaaga
     9841 aggcgacact ctgtgagaat aacacagact gaaatgactt tccactcaca gtttttgtct
     9901 aactatatac aaaaacagaa taaaaaggag gtatttatgc taattgaagc aagaaaaaaa
     9961 gagttacttg ttctacaaat ggtcattcaa aaaaataatt gttctttaca agaattatcc
    10021 aatgacttac atattccaaa acggacaatc aaagaactga tccgaaaaat aaatgtatca
    10081 ctcaagcaat ttttattgat tgatgaattt atttattcta atcataaagg agagatccaa
    10141 accaaagaaa ccgatcaaac taaaaagtta gctgtttttt ctaagttaaa attatgctac
    10201 ctaaaagaat ccaatcgttt taactatttg atgttactaa tcaattatcc acaaactgct
    10261 gtaccaaaaa aatatttact tgaacaactt tatatatcgc cctcctatct cgaaaaactg
    10321 acaaaacagc tcaatcattc cttaaaaaaa ttccatttac ggatcctatc tgtaaaaaat
    10381 tgctgtactc ttgaaggaaa tgagttatct atccgtctct atctttactt ttttctttca
    10441 gatacatttg gaggtaacga ttggccattt tcctcacttg aattaaatgc actaaaaatg
    10501 aacagtacag atgagcaaat agaaaaaatt tcaaaacaag aaaaaaatat ctacttgctg
    10561 ttaactttat tcatattacg aaacaaacaa caggcatatt ttccaaaaac ttcttctgaa
    10621 atcactgaat tgatggactt attgcagcat acacatgatt attcagaata ctttacttct
    10681 ttttcagtga gtcgcccttg tgaagagaca gaaacagaga gagcctactt taattatttt
    10741 ttctattgtt tttttccaaa tcaaatctct tttcgacaaa aacaggagat tggtttttta
    10801 ttttccacaa gcaaaaacct tatttgtcga caagtcggtc aattgatgac ttacttaact
    10861 caacagtttc ctctcaacca tttagaaaat aaaataccaa tttattttta ttttcttgtg
    10921 ttggcagttg tttttttcga actgttgggt gaatccagca gtagtttttc tacactttgc
    10981 tttccagaag ccacgtccaa tcattctagt tcttttatac aggaaaagaa attaagagaa
    11041 aaaatcgata caattttttc aaaaaatggg gaaagaaacc aaatcagtca ataccttagt
    11101 caattgatcc aacacttact acaaacagaa acgaaagagc agttactcat ccatttgcag
    11161 ataaccaaac agtttacagg aaattatcat cttcaaagcc atttgcagca gttatttcgc
    11221 aaagatgctg ttaaaattac cgcatattca gaacatgctg atttgatcat tacagatcag
    11281 catgagaaaa tttcagatga aacggagact ttctatctgg atacaacgca caatacagtg
    11341 ttatttggca agttaataaa agcggttcat gaactgtata tgaaaaaagg ttatgagaac
    11401 aaaacaaaga ggatgtgaca aaattcttgt cacatcctct tattccaaat aaatggtatt
    11461 caatcagcta actctcggta ttagctcaga tcaaagcgct gatttcacaa cttctttatt
    11521 ttaatctctt cggttgccgc cgaacaataa gatcaagcgc aacagctgca ggaatgtcga
    11581 aagcgctgct gcaacataag tcagtgctgc tgcaaataat acgtgtcttg ccatcggtac
    11641 ttcttcttcc gtcagtagtc cgccttcact caaaatttgg attgctcgcc gagacgcgtt
    11701 aaattcgact ggtaatgtca ccaattggaa aagtaatgct aaagaaaaag cgaaaatccc
    11761 gatattgatt aacgtagagt tccagctaag caatacacct accataatca aggggaacga
    11821 aatcatcgaa ccaaagttag ctgctggaac aagtgctgca cgaatcttca atgggacata
    11881 acccgaagca tcttgtaccg catgtccgca ttcatgagct gctacaccta tcgcagcaac
    11941 tgaagtagac tgtgcagttg cttgagacaa actcaacatc ttattacctg aattgtagtt
    12001 atctgtgaga tctccggcaa tttgttgaac accgacatta tttatctgtt gactttgtaa
    12061 tatatattgt gctgcttgtg taccagtcac attgtttttg cttctcactt gatcgtattt
    12121 tcggaaagta ctattgacgt acgctgacgc aattccggaa ataactaatc caagaatgac
    12181 caaaagaaat gtcggatcta aaaaaccata cattccataa ccatacattt tcgtttcact
    12241 ccttttcgtt tactttattt tatcattagt agtaggaaaa gaatgtgaaa agaccttgaa
    12301 tattctttaa ttctttttca caaattccga tttcagtttc atcggtccaa atccttctac
    12361 cttgcaatcg atattatgat cgccttctac taaacggatg ttcttgactt ttgttccttg
    12421 tttaatggca cctgacgcac cttttacttt caagtcttta atcactgtca cgctatcgcc
    12481 ctctaacaga cggtttccat ttgcatctaa taccactaat ccgtcttcta tgacagtttc
    12541 ttgttcttct ttgttccatt cgttcccgca ttctgggcaa atcaacaagc ctcgatcttc
    12601 atatgtgtac tctgagccac attctgggca atttggtaat gtcatcttct ttctccttta
    12661 aaatctttag tgagcactat tgtaacggaa aaagaagatc ttgaaaagat acatttgtga
    12721 tttttactac aaaaggcacg ttttcgaacg aagtatcatt ctgtttttct gctcttatac
    12781 gattggcata tatcttggat ctctttatag atttcctcta cttctgctaa atcttttgca
    12841 ttcgcaccac ttactaatgg atggcctcct ccatgatggc gtttagccaa ttcattgatg
    12901 atcggcccct tagaacgtaa acgtacgcgg taataccctg aaggctgctg aacaaaaatc
    12961 ccccaagcca gcacttcgtc aatcactcca ggaagtgaaa cgatcgaagc tgtctctgaa
    13021 tcatcgattc catatttatc aagaatttct tgcggaagga ttattcttcc tgcaccattt
    13081 tcatccacct ggatattttg ataaagataa ccggaaagtt tagcgacttt catcggcatt
    13141 tgttcaatct ctctgttcaa agcacttgca tcaaatggat aatttctcaa tatcgaagca
    13201 atctctaatg tacgggacgt cgtggaggga tacaaaaagc gccctgtatc tccgacgatt
    13261 cctgcataaa gtaaccgtgc agccttaacg ttcatcttta aagattcagg aaacatcaaa
    13321 gcaaattctg caatcatctc actacagcta cttgcttttg tatttaccca cacaagatct
    13381 ccataagggt catcattggg atgatggtcg attttgatca gtttttctgc caactgatat
    13441 ctttgatcac tgattctggg tgaattagct gtatcagtca cgatgactag cgctccttgg
    13501 tagaagacat cttcaacttc ttgcatttct gctaaaaagc gaagcccttc aatcgtttca
    13561 cctacttgac gtatttcttt ttctgggaaa ctttcccgta atagttcggc taatcctact
    13621 tgtgatccta atgcatcagg atcagggcgc aaatgcctgt ggataatgat tttatcgtat
    13681 ttttttattg tatctactat ttcttgctgt actgtcattt cactcctgct ttctaagaac
    13741 gttccattac ttgacaaaca acgattgctt tggaaacgat ggtgttttca ataaacactt
    13801 cgatatccag tttagcggaa cgtctgccga tttccaatac acgtggacga atgtctaatt
    13861 cgctttccaa ttggatcagc cgcaaataat gtaggttcac ttgttcaatc aagatatttc
    13921 gtttttggtt catcaccatt gttttttgtg cgacatcaga aatgatttcg ctaagtacgc
    13981 caaaagaaat ggttccaacg ccattgacca tttgtggtgc tactacgaat ttgaacttag
    14041 ggttttccaa acgatttcct tcacggtcag tatcaatcgt atggatattt ccagatatct
    14101 gatccgaaat cgtatctgca atctgcggtt gtcgctggac aagctgcatc gctttcatta
    14161 catcttgccg ggtaatcaag ccttccaatg tcaagtcatc ggaaacgacc ggcatgactt
    14221 ctagcccatc ccagatcatt tgatggctaa cagaggcaat actcattgtt ttctttacac
    14281 tgattggttc tttcgtcatc acccgatcga tgatctggtt tggcgatttc cctaaaacat
    14341 cttttgccgt aacaatcccc atcaaacgat gatggcggtt gacgactgga aaacgcgaat
    14401 gctgcgtttc ttctgacaaa cgctgataat cagaaatcgt atctgtctgc tgcaaataat
    14461 gagtcttttc agctggcata tagatatcac tgacaagcat gatatctttt ttgatcaatt
    14521 ggtcgcttaa cgctcggttg atcatggttg cgactgtaaa tgtatcataa gaggtgcgta
    14581 agatcggcat ttcaagatca tcagctagct ttgcaatctc agcagtcgta ttgaatcctc
    14641 ctgtgatcaa tactgcggcg ccatcttcca atgctaattt ttggacttcc gcccggttgc
    14701 cgacgatcat tagtgatcct ggcgtaatat agcgttccat ggcatgttta gtcatcgcgc
    14761 cgatgacgaa tttattcaag accttgtcta atcctgccgc cccgcctaaa acgtcccctt
    14821 caatgatcct gacgacctcg ccaaatgtca aacgttcaat atgttttttt aatttgcgtt
    14881 cgatacggat ggtccctact cgttgaattg ttgaaactag tccgacattt tctgcatctt
    14941 tgattgcacg gtacgctgtt ccttcactga cattcaattc ttttgcgatg cttcttacag
    15001 aaattcgatt gccaacaggt aaactttcaa tatattctaa aatcaaatca tgttttgtcg
    15061 ccattttctg cctacacttc cagcgtttcc gagacgctca ttatttttcc ttcactatct
    15121 tccagtaact ctacaaaaga ttcgggatct tgttcaatga cagggaaagt attgtaatgg
    15181 attggaacta ctttcttggc acgaattgtt tgcgcagcct ttgctgcatc ttctggcccc
    15241 atcgtatagt tatcgccaat cggcaagaaa gcgacatcaa tatcgaattc ttctgcaagc
    15301 aatcctagat cactgaaata agcagtatcc cctgcatgat aaatcgtttt tccttctgct
    15361 tgaataataa ttccgctagg ctcgcccata tactgaacga taccgtctac ttcatagctt
    15421 gaactatgct gtgcatgtac gaattttacc acgccgaatg gaaacgcatg ttttccaccg
    15481 atattcatac cgaatgaatc tactcctctg ctgttcgcat aatcagcaat ctcaacaata
    15541 ctgataattg tggcttgatt ttcttttgca ataggaatca tatctcctat gtggtcacta
    15601 tgaccatgag taatcagcaa ccaatctgtc tttacttctt ctgcagttaa gtctgtcaat
    15661 ggatttcctg taataaacgg gtcaatcatc acgcgttggc cattttccat ttcaattgtt
    15721 aaacaggaat gtccatgata cgtaattttc atattttaca cctcgcgttt tctctgtatc
    15781 ttttttatta aaaacgattt catcacttgc acatcaatga aaaaatatag ctgctaaata
    15841 tattttcatt ggattgatag tacagtatgt acaaagcaat tgtaacagat aatacaggat
    15901 gcaccaagta ccaagcagat ataatctcaa gtttgaggtc tctgctctgc ttagcttctc
    15961 ttctcgtccc ttaactaatt aaatcagcgt aaataggatg gacgatcttt tctaaatcgg
    16021 ctacttttat ccgaaggctt ctcccgattt caccgcttga cacaattact tcttcttttt
    16081 cttttaaaga actgtctgct aaaaaacaat aatcaggatg tgcgagtttt attccaatag
    16141 gggtgtttgc tccgtgggga tatcctgtat gcattaatac aaaatccatt ccaggaaaac
    16201 caactttacg atctttcgtc acttgtctcg tttttttgta atctaagtga tcgttcaaag
    16261 gaatcaatgc gatgatcacc ccagttttgt ttcctttcac tacgagagtt ttacatatca
    16321 aagctggatc aatccctctt ttttgtagtt cttctgtgaa agattcttct accacatgac
    16381 taaaatcaag tggttgatag ctgatctttt gttcttctaa ataacgttcg acttttgttt
    16441 gactcatcat tgattcactc cctttattct atcgtttatt ataaagcgag ggatgctgta
    16501 ttcaaaaat
//
LOCUS       DAFBVQ010000057        16463 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.060, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000057 DAFBVQ010000000
VERSION     DAFBVQ010000057.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16463)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16463)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16463
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.060"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(78..353)
                     /locus_tag="LLC22_002146"
     CDS             complement(78..353)
                     /locus_tag="LLC22_002146"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007208657.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HU family DNA-binding protein"
                     /protein_id="HBK5435402.1"
                     /translation="MANKAELIEKVASATDLTKKDATAAVDAVFSTIQDALANGEKVQ
                     LIGFGNFEVRERAARKGRNPQTGEEIEIPASKVPAFKPGKALKDAVK"
     gene            complement(596..1906)
                     /gene="der"
                     /locus_tag="LLC22_002147"
     CDS             complement(596..1906)
                     /gene="der"
                     /locus_tag="LLC22_002147"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878566.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome biogenesis GTPase Der"
                     /protein_id="HBK5435403.1"
                     /translation="MANPTIAIVGRPNVGKSTIFNRIAGERISIVEDTPGVTRDRIYA
                     KGEWLGREFSVIDTGGIDLGDEPFMDQIKHQAEIAIEEADVIICVVSGREGVTDADEM
                     VAKILYRSNKPVILAVNKVDNPEMRNDIYEFYSLGLGDPYPVSGSHGLGIGDILDEAV
                     KYFSEETEEEDDDTIKFSLIGRPNVGKSSLINAILGEERVIVSDIEGTTRDAIDTHFV
                     SESGQKFLMIDTAGMRKRGKVYENTEKYSVMRAMRAIDRSDIVLMVLNAEEGIREQDK
                     RVAGYAHEAGRGIIIVVNKWDLVKKETNTMRDFEQEIRDEFRYLDYAPIVFVSAVTKQ
                     RLERLPEMIEQVSMNQNLRISSAVLNDIIMDAVAINPTPTDKGKRLKIFYATQVAVKP
                     PTFVVFVNEEELMHFSYERFLENQIRKAFTFEGTSIRIIPRRRK"
     gene            complement(2088..3317)
                     /gene="rpsA"
                     /locus_tag="LLC22_002148"
     CDS             complement(2088..3317)
                     /gene="rpsA"
                     /locus_tag="LLC22_002148"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265592.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S1"
                     /protein_id="HBK5435404.1"
                     /translation="MTEFDQNQENNQSMEDAMKSVQEVKVGDVVKGEVLVIEDKQVIV
                     GIEGAGVEGVVPAKELSTLPVEDISEVVKVGDVLDLVVISTIGKDKENGSYLLSKRRL
                     DAKKVWEDIERDFQEGKVIEAPVTNVVKGGLVVDVGVRGFVPASMVEDHFVADFSDYK
                     GKTLSFKIIEIEPSENRLILSHKAVVENEREEKKKEILSTIHEGDVLSGRVARLTDFG
                     AFVDLGGIDGLVHVSEISHSHVAKPSDVLAVNDDVNVKVLSINPEQERVSLSIKDTQP
                     GPWSEIDTKAPVGTVLDGTVKRLTSFGAFVEVFPGVEGLVHISQISHKHIATPHEVLH
                     EGDEVKVKVLEIHPEEHRIALSIKALEEKPASEEEPKNVESYELPEENTGFTMGDILG
                     DALKEEVEEKATDDSEK"
     gene            complement(3452..4132)
                     /locus_tag="LLC22_002149"
     CDS             complement(3452..4132)
                     /locus_tag="LLC22_002149"
                     /EC_number="2.7.4.25"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345889.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="(d)CMP kinase"
                     /protein_id="HBK5435405.1"
                     /translation="MTQISIAIDGPASSGKSTVAKILAKELNYIYTDTGAMYRAVTYL
                     AITNNVSFSDEEGLVSLIKKYPISFSQQEDGQHVFIASKDVTLEIRQPDVTKAVSEVS
                     AHGKVREELVAVQRKIGERGGVVMDGRDIGTAVLPNAEVKIFLVASVSERAERRFKEN
                     QEKGIPTDLETLTKEIQERDHYDSTRDVSPLKQAEDAVRIDTTGKSIPEVVAAIKAVV
                     LKKGYLLF"
     gene            complement(4181..4816)
                     /locus_tag="LLC22_002150"
     CDS             complement(4181..4816)
                     /locus_tag="LLC22_002150"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315217.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5435406.1"
                     /translation="MSRKDRHQSTENNETQEPWEQPIYDTDDEVSSRSSQRQQKKGNT
                     LFLSLFLILLVLCIAIPAGAYFWIRNGSSNNATAATSSETSTSVVESSTSTTKEESTE
                     TSTVESSTIAEESTVSQDTGVTSESSIAAETTPTSSSEATYQAGDSSSNAAETTPSSS
                     AAAGSTTTVQAGEGPKQVAERAGITTDQLFELNGLDPNNFMLYPGQELRIK"
     gene            complement(4882..6285)
                     /locus_tag="LLC22_002151"
     CDS             complement(4882..6285)
                     /locus_tag="LLC22_002151"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent DNA helicase RecQ"
                     /protein_id="HBK5435407.1"
                     /translation="MLINELKKYFGFDSFRPGQEEIIQALLDGEDTLAILPTGTGKSL
                     CYQLTGYLMEGLVIIVSPLLSLMEDQVTQLQKRGEKRVAAFNSLLSQSERRYVLRHLS
                     QYKFLFLSPEMLTNPSLLEHLKKQNIALYVVDEAHCVSQWGVDFRPEYQQLGKIRKLL
                     GNPVTLALTATATDLVARDIRHVLFDRPPKEIRQSVNRQNISLFVRKTQQKEQELEHF
                     MERAQGAAIIYCATKKEVERLYHLFRERFTVGYYHGGLDAAQRRQLQQQFVKNQLQFL
                     IATNAFGMGIDKSDIRYVVHYDLPDSLENYVQEIGRAGRDQEESAAILFYQSGDERIH
                     YFFNQLSREQRQSFELYLEYATKQAPFDELQKKWMELIQQSEKPENWVERLKRQEKEK
                     EFRLQQMLRYINEENCRRKFILAYFGEKLSEKPQNCCDIDGAKAELLPKRKLFSKTEQ
                     LHWETILLNLFKKNMEH"
     gene            complement(6272..7303)
                     /locus_tag="LLC22_002152"
     CDS             complement(6272..7303)
                     /locus_tag="LLC22_002152"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301241.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5435408.1"
                     /translation="MIVFILSLFSSGHKLRISSLYQLLVGKRTTSVLIYGFTHELLFI
                     HNSFPELKQDKFYQILQKIAQQGWIEINENEAKLTPAGADMLSEHQIEHTGLRFDRYG
                     RTGETSWRLIKFAVQVISNLATGIQDYLPAETSPFYTFQLKKWLSESQLPREILIDTA
                     YESLVQLFSEIPEEAADFLANQLSGNERTGLLPYQLAKNNDESEVYLQQSRCIHLLLA
                     QIEKRPDSLWHALIDSLLQQNFNQSMMITKQMFMNGQTIDQIMAIRHLKRGTVTDHLI
                     EWALFFDDFPYEWILSAETIERLEPNKDSVREWRFSEWNVDGQLDYGEFRLYQIYLLR
                     KEAIQNVNK"
     gene            7334..7555
                     /locus_tag="LLC22_002153"
     CDS             7334..7555
                     /locus_tag="LLC22_002153"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ferredoxin"
                     /protein_id="HBK5435409.1"
                     /translation="MSLLCKLVPERCIACGLCQIEAPDIFDYDEEGIVLFAQEPEAHQ
                     QFVMPEEETYVKKAYQKCPVRAILLENKI"
     gene            complement(7720..8457)
                     /locus_tag="LLC22_002154"
     CDS             complement(7720..8457)
                     /locus_tag="LLC22_002154"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioesterase"
                     /protein_id="HBK5435410.1"
                     /translation="MKIFRRILIGLVIILGLLGGAGYYYIQQNTYEPSSEAQVLVKEG
                     KNKEDYLFFEGEKKNHGKSPLLIFYPGALVEPESYSIWAQDLAKNGFSVAIVKMPLDL
                     AVMGGNKADKVKEDFPNSDYVIGGHSLGGVMASRYVNKNHSDKHLKGVFFMASYPDKK
                     GTLTESAVPVLSITATKDKVLNQEAYQEAKQYLPERTEYVSINGGNHGGFGSYGEQKG
                     DGEAEISNADQQTVIVNTLENWLKKLK"
     gene            complement(8610..9950)
                     /locus_tag="LLC22_002155"
     CDS             complement(8610..9950)
                     /locus_tag="LLC22_002155"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Sapep family Mn(2+)-dependent dipeptidase"
                     /protein_id="HBK5435411.1"
                     /translation="MKKFVTEQHHEQALESLSELIRIPSVLDEADSGQGHPFGKKVIE
                     ALDKVLEISEKLGFRTFKDPEGYYGYSEIGSGDELFGILCHMDVVPAGDENNWETKPF
                     DPTIKDGWLVGRGSQDDKGPSIAAMYAVKALIDAGVEFKTRIRFIFGTDEENLWRCLE
                     KYNEKEEGITQGFAPDAEFPLIYAEKGLLQAYLTGPGTNEFSVKAGGALNVVPDAAPY
                     SGEKLSEVKEALKKHEFDFEEQGEGIVVLGKSIHAKDAAQGVNAISRLAIALSEVFDF
                     GPINFLGKLVQENATGEAVVGKTEDEQSGELTMNFASLEITPEQTKIGVDMRIPVTFK
                     KDDLVAKLTKTAEKYGLTYEEFDFLDSLYVPLDSELVKNLLGTYRDITGDMTEPFVSG
                     GATFARTMNQCVAFGAMFPDTPDFMHQANERWELSSMYKAMEIYAEAVYRLCAK"
     gene            complement(10187..11710)
                     /locus_tag="LLC22_002156"
     CDS             complement(10187..11710)
                     /locus_tag="LLC22_002156"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016627896.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YfcC family protein"
                     /protein_id="HBK5435412.1"
                     /translation="MEQTKKKKFQMPSAYTVLFIIIAVIAVLTWFIPAGHYSVDDAGN
                     IVAGSYERVQQNPQGLWDIFMAPINGMLGVPAGELTKETPAAIPISFFILVVGGFLGI
                     INKTGALDAGIASVVKKFKGKEKMLIPVLMLLFALGGSTYGMAEETIPFYALLIPVMM
                     AVGFDTVVAVAIVLVGSQVGCLASTVNPFATGVASQAVGISMGEGIGLRFLMFVILLA
                     ISIVYVYRYASKIEKDPTKSLVYNQRKEDMKHFDIEAIGRQEVITKKQKHVNVLFFIT
                     FGIMIISLIPWTTLNANFTIFESLTNWLTNLPVLGTVLGKSMLPLGDWYFPEITMLFL
                     VMSIVVAITYGMKESEFVSEFLAGASDLIGVAIVVAVARGIQVVMNNGLITDTILHWG
                     EQGLSSLSSSVFIIITFIFYIPMSFLIPSTSGLAAATMGIMGPMGEFAGVGKDLVITA
                     YQSASGLVNLITPTSAIVMGAVAIARFDVSVWWKFTGKLIAILFVAICVILGVAAMF"
     gene            complement(12088..12699)
                     /locus_tag="LLC22_002157"
     CDS             complement(12088..12699)
                     /locus_tag="LLC22_002157"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ECF transporter S component"
                     /protein_id="HBK5435413.1"
                     /translation="MKNTRVQKMVAVAMFAAIALVLQYFAFPIMPAFSFLKIDFSDIS
                     VLISMFLFGPAAGVATAFLRSVLHLLTTGFSPDNLVGDTASFLSTTIFTFPIYYFFSV
                     KKQHKGRNKFLGVITGTIALTIFMSIANYFVITPLYLMFLGLNATQMLGMSLANYVLI
                     GIVPFNLIKGFIVSAVFLVLHAQLLPWLSRKQHQFEQRHTAVK"
     regulatory      complement(12822..12947)
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00050"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="FMN riboswitch; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="flavin mononucleotide"
                     /db_xref="RFAM:RF00050"
     gene            complement(13029..13745)
                     /locus_tag="LLC22_002158"
     CDS             complement(13029..13745)
                     /locus_tag="LLC22_002158"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878594.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA pseudouridine synthase"
                     /protein_id="HBK5435414.1"
                     /translation="MERLQKVIAHAGITSRRKAEEFILAGRVKVNGQVVRELGIKVGK
                     HDTVEVDEVPIYQEEYGYYLLYKPKGVISAVADDKGRKVVTDLLPMVKERIYPVGRLD
                     YDTSGILLLTNDGDFAQRLTHPKHEVDKVYVAKVKGIATKSMLAPLTKGIKIEGRKTS
                     PAKFQILSVDPKTNHSIVELTIHEGRNHQVKNMLQAVGLPVQKLKREKYGDLTLQGLR
                     PGDYRELNKKEVSSLLNHSK"
     gene            complement(13751..14320)
                     /gene="scpB"
                     /locus_tag="LLC22_002159"
     CDS             complement(13751..14320)
                     /gene="scpB"
                     /locus_tag="LLC22_002159"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337146.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SMC-Scp complex subunit ScpB"
                     /protein_id="HBK5435415.1"
                     /translation="MTKLSELEALLFIVGEEGISNEELSGLLNLSEAEVTSLVKELKE
                     SYTQNSHSALHIFETESHYVLTTKKELAPLLKRYAQGTSNTLSQAAVETLAIIAYKQP
                     ITRAEIEQIRGVQVSGAVQRLAAHKLIEEKGRVEGPGRPILYGTTGYFLDYFGLKSLE
                     ELPDTQEMEISLEEDVSPDLFFDGMNKGE"
     gene            complement(14304..15101)
                     /locus_tag="LLC22_002160"
     CDS             complement(14304..15101)
                     /locus_tag="LLC22_002160"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002315222.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="segregation/condensation protein A"
                     /protein_id="HBK5435416.1"
                     /translation="MASKEKEERVNELTEINIKLDVFEGPLDLLLHLIQQMEIDIYDI
                     PIATITEQYMNYIHTMKTLELAVAGEYLVMAATLMAIKSKTLLPVQEFGTDDEELWEE
                     DPREELVTQLLEYRKYKYAAERLTEKAEERSLYYTKEPMNIDGLADAEKPLKRGQVKK
                     IDLIRAMQKILERKKFSQKVEKTITPDDTTIEERMVFIEERIKRNAHGCTFDSFFESP
                     SKSEVVTTFMALLELMKKGQIIAQQKENYESIMLYPAVGDTEHDEIK"
     gene            complement(15071..15442)
                     /locus_tag="LLC22_002161"
     CDS             complement(15071..15442)
                     /locus_tag="LLC22_002161"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetyltransferase"
                     /protein_id="HBK5435417.1"
                     /translation="MLTHYRKENRKIAMGLLSFHKKLTGKTSLLKEIDTYESEDDYEL
                     FFFTPEGSTNIQGIIGIYWATNDQLIIHDISLNPSYRGENMGFQMLDELQEKYPDVSI
                     RATEITEPYIGKWLAKKKKKE"
     gene            complement(15461..16348)
                     /gene="xerD"
                     /locus_tag="LLC22_002162"
     CDS             complement(15461..16348)
                     /gene="xerD"
                     /locus_tag="LLC22_002162"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309610.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific tyrosine recombinase XerD"
                     /protein_id="HBK5435418.1"
                     /translation="MKEQINDYLHYLNIERGLSANTRQSYERDLEQYLHFLQEQKIAS
                     WQDVDRFLVIRFLEKLHEEKKATATVTRMISSLRRFHQFLRQERITDHDPMQHIDTPK
                     KAQKLPSTLTLTEVEKLIEAPDTTKTLGIRDRAILEVMYATGMRVSELIGLKLGDLHL
                     SLGLVQTVGKGDKERIIPLGDYAIQWLERYLDEARPLLVKDASEMHVFVNNHGKGLSR
                     QGIWKNLKQLVREAGIYKEVTPHTLRHSFATHLLENGADLRTVQELLGHADISTTQIY
                     THITKKRMTDVYKQHFPRA"
BASE COUNT         4623 a         3567 c         2789 g         5484 t
ORIGIN      
        1 tatttattcc ttttctgcta ggaaataaaa agaaaagcac ttgtagccct agagccacaa
       61 gcgctttttc aactgtctta tttaacagcg tcttttaatg ctttacctgg tttgaatgca
      121 ggtactttgc tagctggaat ttcgatttct tcaccagttt gtgggttacg acctttgcga
      181 gctgcgcgtt cgcgaacttc aaagttacca aaaccgatta attgaacttt ttcgccgtta
      241 gctaaagcat cttgaatagt tgaaaataca gcatctactg ctgcagttgc atctttttta
      301 gttaaatcag tagctgaagc aactttttcg attaattctg ctttgtttgc catggataga
      361 ttcacctcct ccacaagaga tatgatagaa atatcattta gttaaaactt tctgagtggt
      421 ccagaagttt aaaaagaaat attgattaac ttcaatattc tgttatcacg atatcatatg
      481 aaccgcttaa tagcaaggtt tttaccaatt ttcacatgct ttttttagtc atagaaacgt
      541 aacaaacgaa actgtctttt tcttttgaaa aaaaaacgtc gatatggtaa aatgcctatt
      601 ttctcctacg agggataatt cggatggacg tcccttcaaa agtaaatgct tttctgattt
      661 gattttctaa gaaacgttca taagaaaaat gcatcaattc ctcttcattg acaaaaacga
      721 caaatgtagg tggtttgaca gcgacttgtg tagcataaaa aatcttcagg cgttttcctt
      781 tatctgttgg tgttggattg attgctacag catccataat gatatcattc aacacagccg
      841 aagagatacg aagattctgg ttcatactta cttgttcgat catttcaggc agacgttcca
      901 accgttgttt agtcactgca gaaacaaaaa cgattggagc gtaatcaaga taccggaatt
      961 catcacgaat ctcttgttcg aaatcacgca ttgtattggt ttctttcttt acaagatccc
     1021 atttattcac gacgataata attccacgac cagcttcatg ggcgtaaccc gctactcgct
     1081 tgtcttgttc ccgaatccct tcttcagcat tcagtaccat caaaacgata tcagaacggt
     1141 caatggcacg cattgcacgc atcacgctgt atttttcagt attttcgtat acttttccgc
     1201 gtttacgcat accagctgta tctatcatta agaatttctg accactttca gaaacgaagt
     1261 gggtgtcgat tgcgtctcgg gtcgttcctt caatatccga aacaattaca cgttcttctc
     1321 ctaaaatcgc attgatcaaa gaggatttac caacatttgg gcgaccaatc aaactaaact
     1381 taatcgtgtc gtcgtcctct tcttcagtct cttcagagaa atacttcact gcttcatcta
     1441 aaatatcacc aatccctagt ccatggcttc ctgaaacagg ataaggatcg cctagcccta
     1501 aggaataaaa ttcatagata tcgtttctca tttctggatt atctacttta ttgactgcta
     1561 aaatcactgg tttattactt ctgtataaaa ttttcgcaac catctcatct gcgtctgtca
     1621 cgccttcgcg tccgctgact acacaaatga ttacatctgc ttcttcaatc gcgatttctg
     1681 cttgatgctt gatctgatcc ataaaaggtt catcgccaag atcaattccg cctgtgtcga
     1741 tcacgctgaa ttctcgacct aaccattcac cttttgcata aatacgatca cgagttactc
     1801 caggagtatc ttcgacaatc gagatacgct caccagcgat gcggttaaaa atcgtagact
     1861 taccgacgtt cgggcggcca acgattgcaa ttgttggatt tgccatatta tttcctcctc
     1921 acaagtttcc aatctcactt agtttaacga atgcattgcc aactttcaag catagattgt
     1981 caattaaacg aagtattttt attccttatt gaaatactaa tcgcttttca aaagaaaaac
     2041 tgagacaaaa gcagctgctt tcatctcagt cacagataca aaatcaatta tttttcagaa
     2101 tcatcggttg ctttttcttc tacttcttct ttcaacgcat cacctaaaat gtctcccata
     2161 gtaaatccag tattttcttc tggtaattca taagactcaa cattttttgg ttcttcttct
     2221 gaagctggtt tttcttctaa agctttgata ctcaatgcaa tacgatgttc ttctggatgg
     2281 atctctaata ctttcacttt cacttcgtca ccttcatgaa gcacttcatg tggtgtcgca
     2341 atatgtttat gtgaaatttg agagatatgg actagccctt ctactccagg gaacacttca
     2401 acaaaggcac cgaagcttgt caaacgttta actgttccgt ctaatactgt gccaactgga
     2461 gcttttgtat cgatttctga ccaaggtcca ggctgtgtgt ctttgattga caaggaaaca
     2521 cgttcttgtt caggattgat agacaacact ttgacattta catcatcatt gacagccaat
     2581 acatcacttg gttttgctac atgactatgt gaaatctctg agacatggac tagaccgtca
     2641 attccgccta ggtcgacaaa tgcgccaaaa tcagtaagac gtgcaacacg tccactgaga
     2701 acatctccct catggatagt tgaaagaatt tcttttttct tttcttctct ttcgttttcc
     2761 actaccgctt tatgcgataa gatcaaacga ttttctgatg gttcgatttc gatgatttta
     2821 aagctcaatg ttttgccttt atagtctgaa aagtctgcaa caaaatgatc ttccaccatt
     2881 gatgcaggga caaaaccacg tacaccgacg tcaacgacta aaccgccttt gacaacattt
     2941 gtaacaggtg cttcgatgac cttgccctct tggaaatctc tttcgatatc ttcccaaact
     3001 tttttagcat ctaaacggcg ttttgaaagt aggtagctgc cgttttcttt atctttgccg
     3061 atcgtactga taacgactaa atctaataca tcaccgactt ttactacttc gctgatatct
     3121 tctaccggca aagttgataa ttcttttgcc ggaacgactc cttcaactcc agccccttcg
     3181 attccgacaa tcacttgttt gtcttcaatg actaaaactt cgcccttaac aacatcgcca
     3241 acttttactt cttgtacgct tttcattgcg tcttccattg actggttgtt ctcttgattt
     3301 tgatcaaatt ctgtcataac acttgtcctc ctaaccaaca ttctgccgta agtacggtac
     3361 tgtttttagt ttaattgatt attcaaaaaa aataaagcga tttcgttcgt tttccttgaa
     3421 aaaacaattg tttttcattt tttttcttaa tttaaaaaag aagataacct tttttcaaaa
     3481 caacagcttt tattgctgca acgacttctg gaatcgattt gccagtcgta tcgatacgaa
     3541 cagcatcctc tgcttgcttc agcggagaga cgtcccttgt tgaatcataa tggtctcttt
     3601 cctgtatctc tttcgtcagt gtttcaagat cagtcggaat tcctttttct tggttctctt
     3661 tgaaacgtct ttctgcacgc tcacttacgc ttgctactaa aaagattttc acttctgcat
     3721 tcggtaatac agctgtcccg atgtctcttc cgtccatgac aacgccaccg cgttccccta
     3781 tttttcgttg gacagcaact aattcttctc tgacttttcc atgtgcagag acttcagaaa
     3841 cagcttttgt gacatctggt tgacggattt ctaaagtcac atcttttgat gctatgaata
     3901 catgctgtcc atcttcttgt tgcgaaaaag agataggata ctttttgatc agcgaaacta
     3961 gcccttcttc atctgaaaaa gatacattgt tcgtaatagc taaataagtt actgcgcgat
     4021 acatggcacc ggtatctgta taaatataat tcaattcttt tgctaatatc ttggcaacgg
     4081 tacttttccc agatgaagca ggcccgtcga ttgcaatact gatttgtgtc atgatataac
     4141 tcctttttct cagaaaaaaa gccgcaaagc gcggctatta ttatttaatt cttaattctt
     4201 gaccagggta aagcataaag ttgtttggat ctaagccatt caattcaaac aattgatcag
     4261 tggtgatccc tgcacgctca gccacttgtt ttggaccttc gcctgcttga acagtcgttg
     4321 ttgaaccggc tgcagctgat gaagaaggtg ttgtttctgc tgcattgctg cttgaatccc
     4381 ctgcttgata agttgcctca cttgaggaag tcggtgttgt ctctgctgca atactgcttt
     4441 ctgacgttac acctgtatct tgagacacag tagattcttc cgcgattgta ctagattcta
     4501 ctgttgaagt ctcagttgac tcctcttttg ttgtacttgt agaactttct actactgatg
     4561 tcgaagtttc agaagaagtt gctgctgttg cattgttgct tgatccattt ctgatccaga
     4621 aataagcacc tgctggaata gcgatacata agaccagtaa aatcaaaaat agcgaaagaa
     4681 ataatgtatt tcctttcttt tgttgtctct gagaacttct tgatgaaact tcatcatctg
     4741 tatcgtagat tggttgttcc catggttctt gtgtttcgtt attttctgta gattgatgtc
     4801 tatcttttct gctcactgtt ttacctccta aactctatcg tgtgtattat accataggaa
     4861 aaagtgtctt gtcctaaaaa atcaatgttc catgtttttt ttaaataaat ttagtaaaat
     4921 cgtttcccaa tgaagttgtt cagtcttaga aaaaagcttc ctctttggca gaagttctgc
     4981 ttttgctcca tcaatatcac aacaattctg cggcttttcg gagagttttt cgccaaaata
     5041 agctaagatg aattttctgc ggcagttttc ttcattaata tagcgaagca tctgctgcag
     5101 gcggaattct ttttcttttt cctgacgttt gagccgttcc acccaatttt ctggtttttc
     5161 agactgctgg atcagctcca tccatttttt ttgcagctca tcaaagggag cttgctttgt
     5221 ggcatattcc aaataaagct caaaactttg tcgctgttct ctagaaagtt gattaaagaa
     5281 ataatggata cgttcatccc cactttgata aaaaagaatt gctgcacttt cttcctgatc
     5341 tctgcctgct cgaccgattt cttgtacata gttttctaga ctgtctggca aatcataatg
     5401 gaccacataa cggatatcag atttatcgat ccccatacca aatgcattcg tagcaatgag
     5461 aaactgcagc tgatttttta caaactgctg ttgaagttgt cttctttgag ctgcatcaag
     5521 accaccgtga tagtatccaa ctgtaaaacg ttccctgaat aaatgataca atcgttcgac
     5581 ttcttttttt gttgcacaat aaatgattgc cgctccttgt gctctttcca tgaagtgttc
     5641 aagttcttgt tctttttgct gcgttttccg aacaaaaagc gagatatttt gccgattgac
     5701 tgattgtctg atctcttttg gtggtcgatc aaatagtaca tgacgtatat ctcttgctac
     5761 taaatctgtt gctgtcgccg ttagtgccag tgtgaccggg tttcctaaaa gctttcggat
     5821 ttttcctaac tgttgatatt ctggacggaa atcaactccc cattgagaca cgcaatgagc
     5881 ctcatctact acatataacg caatattttg ttttttcaga tgctctaaaa gagaaggatt
     5941 agtcaacatt tcgggactca aaaacaaaaa tttatattgc gatagatgac ggaggacgta
     6001 tcttctttca gattgcgaaa gtaaactatt gaaagcagct actcgtttct cccctcgttt
     6061 ttgtaattgc gtcacttgat cttccattag agaaagcagc ggtgacacga tgatgaccag
     6121 accttccatt aaataccccg tcaattgata gcaaaggctt tttcccgttc ctgtaggcaa
     6181 aatagcgaga gtatcttctc catcaagcaa cgcctgaata atttcttctt ggccgggacg
     6241 aaatgaatca aatccaaaat atttttttaa ttcatttatt aacattctgt atcgcttcct
     6301 ttctcaatag atagatttga tacaaacgaa attctccata atctaattgt ccatctacat
     6361 tccattcgct aaagcgccac tctcgcacgg aatccttatt tggttccaaa cgttcgattg
     6421 tttctgcaga gagaatccac tcgtatggaa aatcatcaaa aaacaaggcc cactcaataa
     6481 gatgatctgt tactgttcct ctttttaaat gacggattgc catgatctgg tcaattgtct
     6541 gaccattcat aaacatctgc ttggtgatca tcatgctttg attgaaattt tgctgtaata
     6601 atgaatcgat caaagcgtgc caaagcgaat ctggccgttt ttcgatttgt gctaacaaaa
     6661 ggtggataca tctgctttgt tgcagataaa cctctgactc atcattgttt tttgccagct
     6721 gataaggaag cagccctgtt cgctcatttc cagataattg gttagctaaa aaatctgctg
     6781 cttcttctgg tatctccgaa aacagctgca ccaaactctc atacgcagta tcaatcaaaa
     6841 tttcacgtgg caattggctt tcactaagcc atttttttag ttggaaagta taaaaaggac
     6901 ttgtctctgc tggaagatag tcttgaatac ccgttgccag attagaaatt acttgaacag
     6961 caaatttaat gagccgccaa ctagtttccc ctgttctgcc atagcggtca aaacgcaaac
     7021 cagtatgttc tatttgatgt tcggacaaca tatcagcccc tgcaggcgtt agctttgctt
     7081 cattttcatt tatttcgatc caaccttgct gcgcaatttt ttgcaaaatt tgataaaact
     7141 tatcctgctt caattctgga aaactgttat ggataaacaa aagttcgtgg gtaaatccat
     7201 aaataagtac tgaagtcgtt cgttttccca caaggagttg gtaaagagaa ctaatccgca
     7261 gcttgtgtcc tgatgaaaat agcgataaaa taaaaacaat catattattc tccttaagtt
     7321 aggatggtta gaaatgtcac tactatgtaa acttgtacct gaacgctgta ttgcatgcgg
     7381 tctttgtcaa atcgaagcgc cagatatttt cgattatgat gaagaaggaa tcgttttatt
     7441 tgcccaagaa ccagaggctc atcaacagtt cgtgatgccg gaagaagaaa catatgtaaa
     7501 aaaagcgtat caaaaatgtc cagttcgagc gattttatta gaaaataaaa tataaatata
     7561 aacgaaactt taaaaacgta cactaagttc tctaaacttg aaaataagcc gggatctgtt
     7621 tctcttgttc cgtgaaatcc cgacttattt tgaaagattc atttgctatc tatagttaat
     7681 tgactagttt tttcacggac cctataggac ccatttatat tatttcaact ttttcagcca
     7741 gttttccaat gtattgacga tcacagtttg ctggtctgcg ttagaaattt ctgcctctcc
     7801 atctcctttt tgctcaccat agctgccaaa acctccatga tttccgccat tgattgatac
     7861 atactctgtt ctttccggta aatactgctt agcttcttga taagcttcct gattcaatac
     7921 tttatctttt gtcgccgtga tcgataaaac aggaacagct gattctgtca atgttccttt
     7981 tttgtcggga taacttgcca tgaagaatac cccttttaaa tgtttgtctg aatgattctt
     8041 attgacataa cgacttgcca ttacgccacc taatgaatgg ccaccgatca cataatcgga
     8101 atttggaaaa tcttctttga ccttatccgc tttgtttccg cccatcactg ctagatcaag
     8161 tggcattttg acaatagcga ctgaaaagcc gttttttgct aaatcttgcg cccaaatact
     8221 ataactttct ggctctacga gagcaccagg ataaaaaata agtaatggag actttccatg
     8281 attctttttc tctccttcaa aaaataagta atcttctttg ttttttcctt cttttaccaa
     8341 cacttgcgct tctgacgatg gttcgtacgt attttgctgt atatagtaat aaccggctcc
     8401 accgagtaat cctaaaatga tgactaagcc aattagtatt cgtctaaata ttttcacttt
     8461 ctcccacctt ttctatctga gtgacccctt tttcttaatc aagtatgatt ataccttaaa
     8521 aaaataagag agaaatgcaa actttccagc atcaaataaa aaaagacgga atatccattt
     8581 gaatatccgc cctttttgta tgtttatttt tatttagcac ataaacgata cacagcttct
     8641 gcataaattt ccattgcttt atacatacta cttaattccc atcgttcatt cgcctggtgc
     8701 ataaagtcag gagtatcagg gaacatcgca ccgaatgcca cacactggtt catcgtacga
     8761 gcaaaagtag cgccgcctga tacaaacggt tcagtcatgt ctccagtaat atcgcgatat
     8821 gtccccaata gatttttcac taactcactg tctagtggca cgtataatga atcaaggaag
     8881 tcaaattctt cataagtcaa cccatatttt tctgctgttt tagttaattt agctactaaa
     8941 tcatctttct tgaatgtaac agggattctc atatctacac cgatttttgt ttgttctggt
     9001 gtgatttcca aacttgcaaa gttcatcgtt agctcgccgg attgttcatc ttctgttttg
     9061 cccacgacag cttcaccagt tgcattttct tgaactaatt ttcctaagaa attgattggg
     9121 ccaaaatcaa atacttctga aagagcaatt gccagacgag aaatagcatt cactccttgt
     9181 gctgcatctt tcgcgtggat acttttacca agaacgacga tgccttcacc ttgttcttcg
     9241 aaatcgaatt cgtgtttttt caatgcttct tttacttcag aaagcttttc tccagagtaa
     9301 ggagctgcat caggaacaac attcaacgct cctccagctt ttacagaaaa ctcgttcgtt
     9361 cctggtcctg tcaagtaagc ttgcaataag cctttttctg cataaattaa aggaaattca
     9421 gcatctggcg caaatccttg cgtaattcct tcttcttttt cgttatattt ttctaaacaa
     9481 cgccataaat tttcttcatc tgtaccaaag ataaaacgaa tacgtgtctt gaattccacg
     9541 ccagcatcaa tcaaagcttt gacggcatac attgccgcaa tagaaggacc tttgtcatct
     9601 tgggatccgc gaccaactaa ccagccgtct tttatagttg gatcgaatgg ttttgtttcc
     9661 caattatttt cgtcccctgc tggaacaacg tccatatgac acaagatacc gaataattca
     9721 tctccagagc caatctctga ataaccgtaa tagccttctg gatctttaaa tgttctaaat
     9781 cctagctttt cactgatttc caatacttta tccaaagctt caatcacttt tttaccgaag
     9841 ggatgtcctt gtcctgaatc tgcttcatct agtacggaag gaattcggat caattcgctc
     9901 aatgattcta atgcttgttc atgatgttgt tctgtcacaa attttttcat gatattatcc
     9961 tcctaatatg ttaaaaaggg tcatgtcaaa ttcctccgac acaacctctt cttctcaaat
    10021 aatgacgttt taagcctgct ccatcagcaa gcagaatgtt cttaacaaat gatgaaagaa
    10081 aaaacactca ctgaatggag ctattgactt gtccacgtgc ttatcgatag ccgtttatcg
    10141 gtttcttcat tcttatgata gaccttgtac ttgtatttgt ctaggtttag aacattgctg
    10201 ctacacctag gatcacacag atggctacaa ataatatcgc aattaattta ccggtaaatt
    10261 tccaccacac tgaaacatcg aaacgagcaa ttgctacagc acccattacg atagcagatg
    10321 ttggtgtaat taagtttact aaaccagatg cagattgata agcagtgatt actaaatcct
    10381 taccgacgcc ggcaaattca cccataggtc ccatgattcc cattgttgca gcagctaagc
    10441 cggaagttga aggaatcaag aatgacatag ggatatagaa aataaatgta ataatgatga
    10501 atacacttga agataatgaa cttaatcctt gttcgcccca atgtaagatg gtgtctgtga
    10561 ttaatccatt gttcataacc acttggatac cacgagcaac agctactacg attgctacac
    10621 cgatcaaatc agaagcacca gctaaaaatt cagagacaaa ttcagactct ttcatgccat
    10681 aagtgattgc tactacgatg gacattacta agaataacat agtaatttct gggaagtacc
    10741 agtcacctaa tggaagcatg cttttaccta gaaccgtacc tagtaccgga aggtttgtta
    10801 accagtttgt caatgattca aaaatcgtga aattcgcatt caaggttgtc caaggaatca
    10861 aactgatgat catgatacca aaagtaataa agaacaatac attaacatgt ttttgttttt
    10921 tcgtgattac ttcttgacga ccgattgctt caatatcgaa atgcttcata tcttctttac
    10981 gttggttgta tactaatgat tttgttggat ctttttcgat ctttgatgca taacgataca
    11041 catatacaat agaaatagct aacaaaataa cgaacatcaa gaatcgaaga ccaatacctt
    11101 cacccatcga aatcccaaca gcttgtgaag ctacgcctgt tgcaaaagga tttaccgttg
    11161 aagctagaca gcctacttga gaccctacta atacgattgc tacagctact actgtatcaa
    11221 agcctacagc catcatgact gggatcagta aagcatagaa tggaatcgtt tcttctgcca
    11281 ttccgtaagt agagccgcct aatgcaaata acagcatcaa tactggaata agcatttttt
    11341 cttttccttt gaatttcttc acaactgaag caatcccggc atctagtgcc cctgttttgt
    11401 tgataatacc taaaaatcca ccaacaacca aaatgaagaa agagattggg attgcagcag
    11461 gtgtttcttt agttagctcc cccgctggta cacctagcat cccattgatt ggcgccatga
    11521 aaatatccca cagcccttga ggattttgtt gtactcgttc atatgatcca gcgacgatgt
    11581 tgcctgcatc gtctacacta tagtgcccag ctggtataaa ccaagtaagt acagcgatta
    11641 ctgcaataat aataaataag accgtatacg ctgaaggcat ttgaaatttt ttcttttttg
    11701 tttgttccat cttcttcttc ctttcttttc cgttagagac aacaattttg gctctaatgt
    11761 tattttatca aaaagagtat cagaacaaaa ataataacac gcattttgta aaacttttgt
    11821 tcaaaaagtt cgtttttccc tattccctcc tcttttttca ggtttttaaa gctttcttct
    11881 ttttcattgt agcgtttcct tttttttata aacaaacatt ttcgtctttt aaaaggagaa
    11941 gaatttcaca tttgcaaaga attgattgat ttttatgcat aaatcaaaaa aatactcaaa
    12001 acaaacaaat aaaacgttta cattattgca tgtcttgtat ttttttccaa aaaaaaagac
    12061 caagaaattt cttgatcttt ttgatattta tttgactgct gtatgacgtt gttcgaactg
    12121 atgttgtttt cgacttaacc atggaagaag ttgcgcatgc agcactaaaa agacagcact
    12181 cacgatgaat cctttgatca agttgaaagg aacgatccca atcagtacat agtttgctaa
    12241 agacatgccc agcatctgtg ttgcgttcag ccctaaaaac attaagtaaa gaggcgtaat
    12301 aacgaaataa tttgcgatac tcataaaaat agttagagcg atggttcctg taatgacacc
    12361 taaaaatttg tttcttcctt tatgctgttt ctttacacta aagaaataat aaatcgggaa
    12421 tgtaaagatc gttgttgata agaaactagc agtgtctcct accaaattat ccggagaaaa
    12481 acctgtagtc agcagatgta atactgaacg caagaacgct gttgcaactc cggccgctgg
    12541 accgaataag aacatgctga tcaataccga gatatcacta aaatcgatct tcaaaaaact
    12601 aaaagccggc atgatcggaa aagcaaaata ctgtaaaact aatgcgatcg cagcaaacat
    12661 cgctactgca accattttct gtacacgggt gttcttcatt tgaaatcctc ctgttaggac
    12721 tcctcttcag cgaacttttt gacgtttctc tccaaatgaa aaaactctat tttccaggga
    12781 aaatagagtt agagttattt gatcaagcgt cgtcaaataa gctctatctt ctttatccag
    12841 actatactgt cggtatcgga atttcaccga ttcagctatt tttttgcaaa ataggtcgtg
    12901 gactataacc accggtcggg aatttcaccc tgcccctgaa gacgaacctt atataatttt
    12961 tgtttacata ttcattatac atatctattc aaaaaacgca acatctaaca cttataaaaa
    13021 gtaagtgttc attttgagtg gttcagcaaa ctgctgactt cttttttgtt cagttcacgg
    13081 taatccccag gacgtaggcc ttgtaaagtc agatctccgt atttttcacg ttttagtttt
    13141 tgcacaggaa gaccaactgc ttgaagcata tttttcactt gatgattacg tccttcgtgg
    13201 atcgtcaatt ccacgatact gtggtttgtc ttaggatcca ctgataaaat ttggaattta
    13261 gctggagatg tttttcgtcc ttcgatcttt attccttttg tcaaaggtgc aagcatcgat
    13321 tttgtagcga tcccttttac ctttgcaacg taaactttat ccacttcatg ttttggatgt
    13381 gtcaggcgct gagcaaaatc tccatcattt gtcagtagca agatccccga agtatcgtaa
    13441 tccagtcgac ctacaggata gatacgttct tttaccatcg gcaaaagatc cgtaacaact
    13501 tttcttcctt tgtcatctgc aacagcagaa ataactcctt taggtttgta caataaatag
    13561 taaccgtatt cttcttgata aattgggact tcatccactt ccacagtgtc atgtttccca
    13621 acttttatcc ctaattccct tacaacttgt ccgtttactt ttacacgtcc tgcaaggatg
    13681 aattcttctg cttttcgacg agaagtgatg ccagcgtggg caattacttt ctgcaatctc
    13741 tccattacaa ttattctcct ttattcattc catcaaagaa tagatctggt gacacgtctt
    13801 cttcaagtga aatttccatt tcttgtgtat caggcagttc ttctaatgat ttcaaaccaa
    13861 aataatctaa gaagtagcca gttgttccat ataatatcgg ccgacctggt ccttctactc
    13921 tacctttttc ttcaatcagt ttatgggcag ctagacgctg taccgctcct gaaacctgaa
    13981 ctcctcgaat ctgctcgatt tcagctcttg tgattggctg tttataagcg atgattgcta
    14041 aggtttcgac ggcggcttga gataatgtgt ttgatgtccc ttgcgcatat cgcttaagta
    14101 agggagccag ctctttttta gtcgttaata cataatggct ttccgtttca aaaatatgca
    14161 aagctgagtg cgagttttga gtgtaagatt cttttaattc tttcactaaa cttgtgactt
    14221 ctgcttcgct gagatttaac agtccgctta attcttcatt actgatccct tcctcgccaa
    14281 caataaaaag aagggcttca agttcactta atttcgtcat gttcggtatc tcctactgct
    14341 ggataaagca taattgattc atagttttct ttttgttgcg caatgatctg cccttttttc
    14401 atcaattcta gcaaagccat aaaagtagtg acaacttcac ttttagaagg tgactcaaaa
    14461 aaagaatcga aagtacagcc atgcgcattt ctttttatac gctcttcgat aaataccatt
    14521 cgttcttcga tcgttgtgtc atcgggcgtg atcgtttttt ccactttttg agaaaatttc
    14581 ttacgttcta agattttctg catggcacgg atcaaatcga tttttttgac ttgtcctcgc
    14641 ttcaacggct tttcagcatc cgctaaccca tcgatgttca taggttcttt tgtgtaataa
    14701 agacttcgtt cctctgcttt ttctgtcagt ctttcagctg catatttata tttacggtat
    14761 tctaaaagct gagtgaccaa ttcttctcga ggatcttctt cccataattc ttcatcgtct
    14821 gtgccgaatt cttggacagg aagcaatgtc ttgcttttga ttgccatcaa tgtagcagcc
    14881 atcactaagt attctcctgc aacagctagc tcgagtgttt tcattgtatg gatataattc
    14941 atatattgct ccgtgatcgt agcgatcggt atatcatata tatcgatttc catttgctga
    15001 atcagatgaa gcagcagatc gagaggaccc tcgaatacat ctaatttaat attgatctcc
    15061 gtcaactcat tcactctttc ttctttttct ttgctagcca ttttccaatg taaggctctg
    15121 tgatttcagt tgcacggatg gagacatccg ggtacttttc ctgtaattca tctaacattt
    15181 gaaagcccat attctcaccg cgataagacg gattcaaaga aatgtcatgg atgatcagct
    15241 gatcgttcgt tgcccagtaa ataccaataa tcccttgaat gttggttgaa ccttctggcg
    15301 taaagaaaaa aagttcataa tcgtcttcag attcgtacgt atcaatctcc ttcaacaaag
    15361 aagttttacc tgtcagtttc ttatggaaac tcaatagtcc catagcaatt ttacggtttt
    15421 ctttccggta atgtgttaac atcttctcac cttcctatga ctaagccctt ggaaaatgct
    15481 gcttataaac atccgtcatt cttttcttcg tgatatgtgt ataaatctga gtcgtagaga
    15541 tatccgcgtg acctaacaat tcctgtactg tccgcaaatc agctccattt tctagcagat
    15601 gtgtggcaaa gctatgccgc agcgtatgtg gtgttacttc tttgtaaatc ccagcctctc
    15661 gtactaactg cttcagattt ttccagattc cttgccgaga aagacctttc ccatgattat
    15721 tgacaaatac atgcatttca gatgcgtcct ttacaagtaa tggacgtgct tcgtctaagt
    15781 agcgttccag ccattggatc gcataatcac ctaaaggaat gatccgctct ttatctcctt
    15841 ttccaactgt ctgtaccagt ccaagagaaa gatgaagatc tcccaatttc aatccaatca
    15901 attcactgac gcgcatccca gtagcataca tgacttccaa gattgcacga tctcttatcc
    15961 ctaacgtttt tgtcgtatca ggtgcttcaa tcagcttttc tacttctgtc agagtcaatg
    16021 tacttggtaa tttctgtgct ttcttcggcg tatcgatatg ttgcatcgga tcatgatcag
    16081 tgatacgctc ttgccgtaaa aactgatgga atcttctgag acttgagatc atccgagtaa
    16141 cagttgctgt cgcttttttt tcttcatgca acttctccag aaaacggatg actaaaaagc
    16201 gatcgacatc ctgccatgaa gcaattttct gctcctgtag aaaatgcaag tactgttcca
    16261 aatcacgttc atagctttgt cgtgtattgg cggacaatcc ccgttcaata ttcaagtagt
    16321 ggagataatc gttgatttgc tctttcataa taatccccct catgcctctc tatcatatca
    16381 gataccgctt cattctgata gtctttttcc ataatctgag caaagaaaaa gccgtctaga
    16441 cactcagacg gactggtttc ttt
//
LOCUS       DAFBVQ010000058        15471 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.061, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000058 DAFBVQ010000000
VERSION     DAFBVQ010000058.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15471)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15471)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15471
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.061"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..1126)
                     /locus_tag="LLC22_002163"
     CDS             complement(<1..1126)
                     /locus_tag="LLC22_002163"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBK5435419.1"
                     /translation="MYKGHRIRAGDQHLVYHFVLGWLLALFIGWMSVFYFQEFRQFDI
                     SKLSLSTIEIVWSIKDLVCLLGSLAFSGAMILLYIHFFLDHWRSLWHRQKLARMILEN
                     HWYEVKQTQSEGFFKDLNSSRTRETISYFPKIYYRMKDGLLSIRVQISLGKYQDQLLK
                     LEKKLESGLYCELVEKELKDSYVEYTLLYDMIANRIGIDEVVAENGTLRLMKNQVWAY
                     DSLPHMLIAGGTGGGKTYFLLTIIEALLKSDAELFILDPKNADLADLGTVMPHVYSQK
                     EEISACVEDFYERMMARSKAMKEMSNYKTGENYAYLGLPPNFLIFDEYVAYMEMLTTK
                     ESAVILNKLKQIVMLGRQSGFFLILACQRPDAKYLGDGIRD"
     gene            complement(1209..1544)
                     /locus_tag="LLC22_002164"
     CDS             complement(1209..1544)
                     /locus_tag="LLC22_002164"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="damage-inducible protein J"
                     /protein_id="HBK5435420.1"
                     /translation="MEINVEHILDCLDQYGKGELTEEQLVKALTSDEKMFLIIHQGLL
                     GENSDSEEDSDVLDWLGEEESFFIVVEVNENLCRQAESILEEIGVEMPDAIEGFLNQL
                     VETKQLPSS"
     gene            complement(1554..1928)
                     /locus_tag="LLC22_002165"
     CDS             complement(1554..1928)
                     /locus_tag="LLC22_002165"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5435421.1"
                     /translation="MRLTEGIVVDSGLTFGKLRFSALRREVRKQNEDGTIGNEVKERT
                     YNLKSSAQGRMIQVSIPANVPLREFAYDAEVELVNPIVDTVANYVFREGTTVNWFIKA
                     DDLVLKRQPNQGNPTNQNERKK"
     gene            complement(1941..2255)
                     /locus_tag="LLC22_002166"
     CDS             complement(1941..2255)
                     /locus_tag="LLC22_002166"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016171806.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5435422.1"
                     /translation="MELKFVVPDMAETFGKLSYAGEGEIITEGYGRNTTVIGRSYHLY
                     SSKQRADDIEVVVAAEAGEKDFDQDQPLKAVNPHLVAKGYEIENRGFTDYVLYVDDLV
                     KA"
     gene            complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="LLC22_002167"
     CDS             complement(2368..5595)
                     /gene="fss3"
                     /locus_tag="LLC22_002167"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010729285.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="fibrinogen-binding MSCRAMM adhesin Fss3"
                     /protein_id="HBK5435423.1"
                     /translation="MYKKQKKKLCVLTILSLAVQAIVGAIAPTITFADEITHPQTVTV
                     ELDLAHQYAVEGTFSDGRPMSEVTVPHYAVYNGFKQDIFCIEPGVPIYNEFTPGYEKN
                     PLPDMSDKAKLVSVLWKKVGTDADTHIVAQKMIWQEVNGYTLHSIKRSDGSAVNIAAI
                     EAKINQAIDDYQKKPTFHNSTAKTVLGQSTTVTDTNNLNLSEFDEVVENAANIDYRVN
                     GNQLIITPNANSKESGVLTLKKSAGTGTPVAYKKAGQQTLMAGAIDKPNTYTIKIDVE
                     TEGSLKIKKVDKESGDVVPGTVFHLDFGKTLPAKDVTTDKEGIATLDEIPHGTKVTIT
                     EKSVPAPYTIDTTPMTTTIKAGETIYVTSKNAREKGQIILDKSGVETGSDLWNDNYSL
                     AGNTFAIRKDSPTGEIVQEMTTDENGHAETPKEIANALELGTYYVTETKASHGFVNTF
                     KPVKVELKYANQTVALVTSNVKGQNQEVTGETTLTKEDKDTGDKAQGKAVFEGAEYTL
                     FTAKDGKAVKWSEAFKPELAKGTKGSDETVTLTLDEKNQVAVKHLAINEYYWQETKAP
                     EGYSLDETKYPVSIKKVDDSEKNAVITRNVTAKEQVIRFGFDFFKFAGSAAGTTETGF
                     NDLTFKVSPLEGTNEITGAEDEATTAYNEQLGFDGYGKFENLPYGDYLLEEVEAPEGF
                     QKITPLEIRSTFKENKEDFVKSEYVFTITEQDQKQPIKTVTVPYEKLTNKAFSVSLNR
                     LMLYDLPEEEDSLTSLATWKDGNKELTSLDSTELVDKLSYNLHEIKEDWYVVAQAIDV
                     DATKAAQEKDEKAKPVVIAETSATLANKEKTGTWKIQHKLTAEQVLNKTIVLFNYVYE
                     NKEAFEAGDKPVAKDVSLNNQAQTVSCTVEHHVSIQTKAHLENGSQTFTHGDVVDMFD
                     DVSITHDVLDGSKEAFETILYALLPDGTNKEIWKSGKIDYEVNDKEFTKTVLAKKVDT
                     GKYPEGTKFTFAEINYDKDGNINGKHNEDLKEKSQTLTPKEVPTILSTPKQPETPTVP
                     SGSQESSPTVKTFPQTGEKNSNVLLFIGFTLIFATAGYYFWNRRN"
     gene            complement(6009..7175)
                     /locus_tag="LLC22_002168"
     CDS             complement(6009..7175)
                     /locus_tag="LLC22_002168"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318021.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5435424.1"
                     /translation="MSIQKYTTKSGARYSVRLYVRKDENGKQEYYVKKGFKTEKEAKL
                     HEARKKVEIEDTGYHKPSNDLFITVYEEWLPSYRNRVQETTYQRTKDLFRLHILPKFG
                     NKSISKITPVHCQNAVNEWALKFKNIKQLKSYSSQIFEYAIFAELLHRNPMANTNLPK
                     REKKENENYFSLEELKAFWDILNKEEPLKHILIFQLLITTGIRKGELAALHWSDIYFE
                     EQLMYVRKSYATIRNEEKNARRKTVRIQKNTKNISSERILPIDAQTIEMLKIWKKEQA
                     RELLQFGINTNTKNQLIFTYVNADGDINQPLHADYSNNILKRLEKKYKFKHVTIHGFR
                     HTHATLLLEGGASIKETQDRLGHKNAETTLNTYSHVTEKAQRNALEKFIAYTGL"
     gene            7200..7526
                     /locus_tag="LLC22_002169"
     CDS             7200..7526
                     /locus_tag="LLC22_002169"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321715.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435425.1"
                     /translation="MASWLIEEIENERRKIMDAGITVMLDKQQTNQLKNYVFEMTKEA
                     IDQARIDAGLERPFLKGKEMAKYLNVSYTTFLKFKRMGLPVILLEKMELFSKEECKKW
                     ILSHQI"
     gene            7679..8731
                     /locus_tag="LLC22_002170"
     CDS             7679..8731
                     /locus_tag="LLC22_002170"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBK5435426.1"
                     /translation="MNEKEVESLVEKQGYSNSDIYAELYYQYPIFLNVNEKYKKMKLS
                     SKLVYMLLKDRNRLSLKNNLYDENQKIFLIFEIKNLVEISGMSKNTILSALDELQKVK
                     LLVKRKNGFNKSKMQMFPNFYYLLKPVLCKDDVYKINKITHQENRQKNLIVQNLNYGT
                     NQYSVDSSKFELCDTSMKTRDKNNFADSSKNELELYKSYKDSKDIKESHNDDLLESLS
                     TKNNKLDEELIETFIEENLLKQIWGESIVNCLKLASNSDYRQFDNWYKKFKYAIRSAE
                     KEQKIQLKIIYEICNNKYFVDHVREQLSMTLRDLIRRAKTDHRIKQKDDYIFASLKNK
                     ALELIELQISEGIDKQ"
     gene            8807..9025
                     /locus_tag="LLC22_002171"
     CDS             8807..9025
                     /locus_tag="LLC22_002171"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435427.1"
                     /translation="MIKNRLIDQVWCLDQNTDSLELIETICFNTIVLDLRAENDNCVT
                     HVIINQKMAQKLSESLRKWAKGGNDENN"
     gene            9012..11585
                     /locus_tag="LLC22_002172"
     CDS             9012..11585
                     /locus_tag="LLC22_002172"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387144.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435428.1"
                     /translation="MKIIEKKIANKKINWLVVNFLVLIAMIIFTSNIAHASIFNWFDD
                     TKSQTEFLNNSLYRPYLKKYNGDFLSQFGIWLGWAVVKGMFTVTDSIQNMIPDVLDLF
                     NFIESTGLNNVYQSAVNTIVIGLMILSLMFVGYKMITGKGTVDLKSVGMNVVMSIALI
                     LLMPTMISSGIQFAKTFYKDSTTITNSDDGVAWSLIKQGVTDLAYINKTDQYSSIDKT
                     EDRNNLTRKNFQQTDLTQVLTDKVIDKLEKENPIADNLRYELVENSNNEFVATKFSDN
                     FLSTFSDSLKSGYYRYQANLWGISIGLTALAIAYVFSAFVIITAILELAFKRVLGVLV
                     FATDIETGQRSKVVLSDILQCYLTVGFQGFGLSMFAMFINFLNSGQGISTNIFIKTIA
                     YICAVFVLIKGSGTVMRYFGVDIGLKEGYGQLASAFGMGAMLFRKGSNGFNRAKGSGE
                     GEDRKPEKNFGETLSKKAGKTGRALGYAHERGLSGLASDGATMASERATKPFKSMRDI
                     ANDTKNKFKEGLDDGTVSAINKNSKPMLAKNKEDETGKYADSVPTRLSDRKDGAKVEN
                     ADRIMSSSERMREAMKNNAESNNNPASAIQQKVQQDIEERKNAMHGQAKSAEELINQK
                     RHEAKYTPEAMNREEIMLRKRVEGRTGANIDGKEALTKERIQEAKNSNTGLEKLVKEN
                     PQNSTSSHGGRSVDVRENIQGSLNGHVGRNVDVRENLQSSSNAQGTKTIDVRENLQSS
                     STSQPKTVDVRENVQNSTSSQGFKTVDVRENIQKDSGEMKEKTQKINIVEDRKSAKKF
                     DSNHETVIIDSEIRENDKGSKSRRRFTYEDNELFRDTLNDPNPLFDNLLRNKRGGLSC
                     N"
     gene            11576..11773
                     /locus_tag="LLC22_002173"
     CDS             11576..11773
                     /locus_tag="LLC22_002173"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322532.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435429.1"
                     /translation="MQLILKISTHDFLELDELCESVKNATNEKITVTNYIELMIQEEL
                     KMKNEIESNFKCCSLEKNVRG"
     gene            11777..12388
                     /gene="mobC"
                     /locus_tag="LLC22_002174"
     CDS             11777..12388
                     /gene="mobC"
                     /locus_tag="LLC22_002174"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322856.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid mobilization relaxosome protein MobC"
                     /protein_id="HBK5435430.1"
                     /translation="MDDKQKMYEKNRKHSEALNFRVDKKTYLELTLIAKQRGISRADV
                     CRERLKGLKYEPPLLAEDDRVVLTKQLNQIGNNLNQAVKALNIIAKYFREESEDKKEK
                     SLHFSFDASRYNIFKDELANSIAKKLMISYPDDIFLESNRSAPSFFKLSEVEKEYFEY
                     WIEKQTRPGTKEEYSQKVDRNLIHSIQIIASLKDEVKQLWELL"
     gene            12373..13764
                     /locus_tag="LLC22_002175"
     CDS             12373..13764
                     /locus_tag="LLC22_002175"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352353.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBK5435431.1"
                     /translation="MGATITSKGRKKNLSSLLQYAANPSKKEKCVAVSGINCSDDSEE
                     ALQEMNLVRTKMNKSKDIAQAFHVIHSFDKSTSKELSIDKMHEIAVEFAEKAFPNSQI
                     IVASHNDKDHFHSHLVINNINMETCKRLRIDPKDLELMRKINDQVLNEHGLESVNNEY
                     YENLEKRTNLYSNDPSKMKYGKINYQEFVQNAIEATLEKCEVNSFEDFSDHLAKEYNI
                     EVYQFSKTNNKLGYVLYKQGVNFYERRGELITLGRDKQSRKEKSQYVERTFSARKLGK
                     RYSFESVSEQLEKNLEESHIKNFFNMEREQVMSLISGVNYKTGELNVPFVELDSIAQK
                     QFSDREGDEKFIKYDDFLREVDKHFVNTMSLEDDQEYTIKLHTDVNPQTLRSAKSKTI
                     SIKKTDQKELFLPAKGFENCSHTPSAKQIHYQISRIMNDDVKMYRAKKDYEFTQQMIE
                     NQQKRQQNFEMEF"
     gene            13980..14294
                     /locus_tag="LLC22_002176"
     CDS             13980..14294
                     /locus_tag="LLC22_002176"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320994.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435432.1"
                     /translation="MNYPYFKVSASEETKEIFNNFYNQNKGIFGSKANMFRVMVSNLP
                     VLASPSNNKFNDPESIKFEQKISELESMISNEVIEKLDDIDQKLSYSLKNKYKTEEKK
                     DV"
     gene            14287..14781
                     /locus_tag="LLC22_002177"
     CDS             14287..14781
                     /locus_tag="LLC22_002177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435433.1"
                     /translation="MFKVYFPFQWLVKGILLVLLGLILFGSYLTIKARHFPEEKPIKI
                     VTKDLKIGETYQADGVELTFKNIEVTEKRNEFAQHDRVLQVTYTLINDTENPIRPQQW
                     SIENKDGEELYEYDMILDNPEYIESGKEETVNYYYELPIERQDYQIVVRRENGYIVGL
                     PFTL"
     gene            14849..15163
                     /locus_tag="LLC22_002178"
     CDS             14849..15163
                     /locus_tag="LLC22_002178"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331275.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435434.1"
                     /translation="MAEENKVVPFETLVINKEEFEQLFLDFFIQYDMIYDFSSSLDLF
                     ELEAEIIENSREKNGKIIISVEKFNELFSQTFEIDPDYYQPQEVFREFRNKIIGFSQT
                     TK"
     gene            15262..>15471
                     /locus_tag="LLC22_002179"
     CDS             15262..>15471
                     /locus_tag="LLC22_002179"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331276.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5435435.1"
                     /translation="MDTITPTNFKENIGKVLQEVVHSNSEIEITRDSKNGLNDGVIMI
                     SKRKWELLQEELYLQRTGTWAYVSDL"
BASE COUNT         5203 a         2602 c         2783 g         4883 t
ORIGIN      
        1 gatcgcggat tccgtctcct aaatatttcg catccggcct ttggcaagcc aaaatcagaa
       61 agaaaccaga ttgacgaccc aacatcacga tttgtttgag cttattcaaa atcaccgcac
      121 tttctttcgt cgttaacatc tccatataag ccacgtattc atcaaagatt aaaaagttgg
      181 gtggaagtcc aagataggca taattctctc ctgttttgta gttagacatt tctttcattg
      241 ccttgctacg agccatcata cgttcataga aatcttccac acaagcagaa atttcttcct
      301 tttgtgaata aacatgaggc atcaccgtac ctaaatcagc taaatctgca tttttgggat
      361 cgaggataaa caattctgca tctgacttca atagtgcttc gataatggtg aggaggaaat
      421 aggtcttccc tccacccgtg ccaccagcga ttaacatatg gggtaaagaa tcataagccc
      481 atacttgatt tttcatcaat cgcagagtcc cattttctgc cactacttcg tctatcccaa
      541 ttcgattggc gatcatatca tacagtaaag tatactccac ataggagtct ttgagttcct
      601 tttctactaa ctcacaatac agtccgcttt ctaacttctt ttccaatttt aaaagctgat
      661 cttggtattt cccaagtgaa atttgaacgc gaatagacag taatccatct ttcattcgat
      721 aatagatttt ggggaagtaa ctgatagtct ctctggttcg gctactattc aaatctttga
      781 aaaagccttc actttgagtt tgtttcactt cataccaatg gttctctaga atcatccgag
      841 ctagcttttg tcgatgccac aagcttcgcc aatgatcaag aaaaaagtga atataaagca
      901 atatcatagc tcctgaaaaa gcgagacttc caagcagaca tactaaatct tttatagacc
      961 aaacgatttc aatagtagaa agtgatagct tagaaatatc aaattgtcta aactcttgaa
     1021 aataaaagac gctcatccaa ccgatgaaca gagcgagtag ccagccaaga acaaagtgat
     1081 aaaccaagtg ctgatctcct gcgcgtatgc gatgtccttt gtacattttg atggtttcca
     1141 cctccaatcg aaaaagccca ataggatttc attaggcaat ttcaaaaagt tatgctagtc
     1201 atttactgct acgaggaggg gagttgtttc gtttcaacca attgatttaa aaagccttca
     1261 atagcatccg gcatctccac accaatttct tccaaaatgg attctgcctg ccgacataag
     1321 ttttcattta cttcgacaac tataaagaaa gactcttctt ctcctaacca gtctagtaca
     1381 tcagagtctt cttcactgtc gctattttct ccaagtaaac cttgatgtat aatcagaaac
     1441 attttttcat cagaggttaa tgctttaacg agttgttcct cagtcagctc gccttttcca
     1501 tattgatcga gacaatctaa aatatgttca acattaattt ccataatctt cacctatttc
     1561 tttctttcat tttggttcgt aggatttcct tgattcggct gccgcttcaa gactaaatca
     1621 tccgccttaa tgaaccaatt aacggtagtt ccttctcgaa aaacataatt ggcaacggta
     1681 tccacgattg gattgaccaa ctctacctct gcatcataag caaactcgcg taagggtaca
     1741 ttagctggga tactaacttg aatcattcgc ccttgtgcag aggattttaa attataggtt
     1801 cgttctttta cctcattacc aattgttcca tcctcatttt gcttccgtac ttctcggcgt
     1861 aatgcggaaa aacgcaactt cccaaatgtt aaacctgaat ctacgacaat accttctgtt
     1921 aatctcatct tcttttcctc ctatgctttc actaaatcat caacatacaa cacgtaatca
     1981 gtaaacccac gattctcaat ctcatagcct ttggcaacca aatggggatt cacggctttt
     2041 agcggttggt cttgatcaaa atccttttca ccggcttccg cagctactac cacctcaata
     2101 tcatcggccc gttgcttact ggaatacaaa tgataactgc gaccaatcac cgtagtattc
     2161 cgtccatatc cttctgttat aatttctcct tcaccggcat aacttaactt tccaaaggtt
     2221 tcagccatat ctggcacgac aaatttcaat tccatcttct tttcctcttt tcattgttag
     2281 ttttggatac aaaaatagcg cgactacttt tttaggaggc ggtcgcgcac gttggttctt
     2341 aggatttact tgtatcatct catcacctta gttccggcga ttccagaaat aatagcccgc
     2401 cgtcgcaaaa atcaaagtaa aaccaatgaa cagtaaaaca ttggaatttt tctccccggt
     2461 ttgagggaag gtcttcactg tgggactaga ttcttgagag ccacttggaa cagttggtgt
     2521 ttccggttgt ttcggcgtac ttagtatggt tggaacttct tttggtgtta aggtttgaga
     2581 tttttctttc aaatcttcat tgtgttttcc attgatattc ccatctttat cgtaattgat
     2641 ttccgcaaaa gtaaacttgg ttccttctgg atattttccg gtatctactt ttttcgcaag
     2701 cacagttttg gtgaattctt tatcatttac ttcataatca atcttgccag atttccaaat
     2761 ttctttgttt gtaccatccg gtaataaagc atacagaatt gtttcgaaag cttcttttga
     2821 gccatccagt acatcatgag taatcgacac atcatcaaac atatccacca catcaccatg
     2881 agtaaaggtc tgagaaccgt tttctaggtg ggcctttgtt tggatagaaa catggtgttc
     2941 cactgtacaa ctgacagttt gggcttggtt attcaagcta acatccttcg ctactggctt
     3001 atcgcctgct tcaaaagctt ccttattttc atacacatag ttgaataaga caatagtttt
     3061 atttaaaact tgttcggcgg ttaatttatg ctgaattttc caagttcctg ttttctcttt
     3121 gttcgccaac gttgcgcttg tttctgcaat caccactggt ttggcttttt catctttttc
     3181 ttgggcagct tttgtcgcat ccacatcaat ggcttgcgct accacatacc agtcttcttt
     3241 gatttcatgt agattgtaac tcaatttatc aactagctcg gtagaatcca gagaagttaa
     3301 ttctttgttt ccgtctttcc aagtcgcaag agaagttaaa ctatcttctt cctcaggcaa
     3361 atcatagagc attaaacggt tcaaactaac agaaaatgct ttgttcgtca gcttctcgta
     3421 aggaacggtc accgttttaa ttggttgttt ttggtcttgt tcggtaatgg taaagacata
     3481 ctcactcttc acaaagtctt ctttgttttc cttaaaagta gaacggattt ctaatggcgt
     3541 aatcttttga aaaccttctg gggcttctac ttcttcaagt aaataatccc cataaggaag
     3601 attttcaaac ttgccataac catcaaaccc taattgctcg ttataagctg tggtcgcttc
     3661 atcttcggca cctgtgattt cattggtccc ttccaatggc gacactttaa aggtcagatc
     3721 attgaagcca gtttcggtag tgcccgcagc tgatccagca aatttaaaga aatcaaagcc
     3781 aaagcgaatc acttgttctt ttgccgtaac atttcgggta atcacggcat ttttttcgct
     3841 atcatccacc tttttgatgg atacaggata ctttgtttca tcaaggctat atccttcggg
     3901 cgcttttgtt tcttgccaat aatactcgtt gatagctaaa tgtttaacgg caacttggtt
     3961 cttttcgtct aaagtcaaag tgaccgtttc atcagaacct ttcgttccct tcgctaactc
     4021 tggtttaaaa gcctcactcc atttaacagc ttttccatcc ttagcagtaa acaaggtgta
     4081 ttcagcaccc tcaaagactg ccttaccttg tgctttatcc ccagtatctt tgtcttcttt
     4141 cgtcaaagtg gtttcgccag tgacttcttg attttgccct tttacgttac tggtaacaag
     4201 ggctacggtt tgattggcat acttcaattc gacttttaca ggtttgaacg tattcacgaa
     4261 cccatgacta gctttagttt cggtcacata ataggttccc aattccaacg cattagcaat
     4321 ctcttttggt gtttccgcat gaccgttttc atccgtggtc atttcttgaa cgatttcacc
     4381 ggttggactg tctttgcgaa tggcaaacgt attaccagct aaggaataat tgtcattcca
     4441 aagatcactc cctgtttcaa ctccgctttt atccagaatg atttgccctt tttcccgtgc
     4501 gttttttgaa gtcacgtaaa tggtttcgcc tgctttaatg gtggtagtca tgggggtggt
     4561 atcaatcgta taaggcgccg gtactgattt ttcggtaatg gttacttttg taccatgagg
     4621 aatctcatcc aatgtagcaa tgccttcttt gtcagtagtc acgtcttttg caggtaaagt
     4681 ttttccaaag tctaaatgga aaaccgttcc tggtacaaca tcacccgatt ctttatcgac
     4741 ttttttgatc tttaaagaac cctccgtttc cacatcaatt ttgattgtgt aggtattagg
     4801 tttatcaatc gccccggcca ttaaagtctg ttggccagcc tttttatagg cgacaggtgt
     4861 tccggtacca gcagatttct taagcgtcag cacaccactt tcttttgaat tggcatttgg
     4921 ggtgattatc aactgattac cattcacacg ataatcaatg tttgcggcat tttccacaac
     4981 ctcatcgaac tctgacaaat tcagattatt cgtatccgtc acagtagtcg attgccctaa
     5041 tactgtttta gccgtactat tatggaaggt tggtttcttc tgataatcgt caatggcttg
     5101 atttattttt gcctcaatgg ctgcgatatt tacggcacta ccatctgatc gttttattga
     5161 gtgaagggta tacccattaa cttcttgcca gatcatcttc tgtgccacaa tatgagtatc
     5221 tgcatctgta cctacttttt tccataaaac ggaaactaat ttggctttat cggacatatc
     5281 tggtaacggg tttttctcat agccaggagt gaactcattg taaatcggga ctcctggttc
     5341 aatacagaaa atatcttgtt taaagccgtt gtacactgca taatgcggaa cagtgacttc
     5401 tgacattgga cgaccatcac taaaagttcc ttcaacagca tattgatgtg ctaaatctag
     5461 ttctacggtt accgtttgtg gatgggtaat ttcatcagca aaagtaatcg taggagcaat
     5521 tgctccaaca attgcttgaa cagccaaact caaaatagtt aatacacata atttcttttt
     5581 ttgtttttta tacatgaaat gttctccttt caaattaagc acaaaaaaat aagatgctcg
     5641 cttgaacatc tttgtttata aagtcttttt aaaattttta ttgactgaat agaatggatt
     5701 tgagaatgaa tgagcctaaa aatttaatct aaaatacgaa atatactgcc tttaaattag
     5761 aacacatttt agaacacaaa catttcaaat ttaatcaaat ataataaaat atatttacgg
     5821 gaaaaccttt ataaatcaag gtttttcaaa cttattcaat gatacgaaga aaccaggtct
     5881 taagaaagca cgtaaagctt cacagttttc aaaacgttaa tcgttgttat accaacgatt
     5941 tcagacactt tctcattgcg agaaggtgtc tttttttcgt tctggtaatg agaaaggtaa
     6001 tgacaatatt ataaaccagt gtaagcaatg aatttttcta acgcatttcg ttgagctttt
     6061 tcagtaacat gagaataagt gttaagggta gtttcagcat ttttatgacc caatcgatct
     6121 tgtgtttctt tgatacttgc tccaccttct agtagaagag tagcgtgagt gtgccggaat
     6181 ccatgaatag taacgtgctt aaatttatat ttcttctcta aacgtttcaa tatattattt
     6241 gaatagtccg catgcaaagg ttgattaatg tcaccgtctg catttacata ggtaaagata
     6301 agttgatttt ttgtatttgt atttatgcca aactgcaaaa gctctcgagc ttgttctttt
     6361 ttccagattt ttaacatttc aatagtttgt gcatcaattg gtaatattcg ttcggaagat
     6421 atattttttg tatttttttg aatcctgaca gtttttcttc ttgcattctt ctcttcattt
     6481 cgaatagttg catagctctt tctaacatac attagctgtt cttcaaaata aatgtcagac
     6541 caatgaagag cagctagctc tcctttacgt ataccagtag taatcaaaag ctggaagatt
     6601 aaaatatgtt ttaaaggctc ttctttattg agaatatccc aaaaagcttt tagttcttct
     6661 aatgaaaagt aattttcatt ttctttcttt tcccgctttg gtagatttgt atttgccata
     6721 ggatttcggt gtaatagctc tgcaaaaatg gcatactcaa atatttgaga gctgtaagac
     6781 ttaagctgtt tgatattctt gaattttaaa gcccattcat tgactgcatt ctgacagtga
     6841 acaggagtaa tcttagaaat ggacttattc ccgaattttg gtagtatatg caagcggaaa
     6901 aggtcttttg tacgttgata tgtcgtttct tgtacacgat tcctataaga aggcaaccat
     6961 tcttcataca ctgttataaa caagtcatta gaaggcttat gatagccggt atcttcaatc
     7021 tcgacctttt ttcttgcttc gtgtaacttg gcttcttttt cagttttaaa cccttttttt
     7081 acatagtatt cttgctttcc attttcatct ttacgaacat acaagcggac actatatcgt
     7141 gcaccgcttt ttgttgtgta cttttgtatt gacataacta atctctccaa tctgataact
     7201 tggcgagttg gctgattgaa gaaatagaaa atgagaggag aaaaataatg gatgcaggaa
     7261 ttacagtaat gttagataaa caacaaacga atcaattgaa aaattatgtt tttgaaatga
     7321 caaaagaggc tattgatcaa gcaagaattg atgccggatt agaaagacca tttctaaaag
     7381 gaaaagagat ggctaaatat ttgaatgtat catatacaac ttttttgaaa tttaaaagaa
     7441 tgggattgcc agttatttta ttagaaaaaa tggagttgtt ttcaaaagaa gaatgcaaaa
     7501 aatggatatt gagtcatcaa atttaaaaaa cacctcgttt tttaaatttg atgaagtaga
     7561 aaaaattaaa aagagtgttc ccgtcagttt gcagatcggg ggaacactca ataataaagt
     7621 tctgagaaaa ctttatttga atctattata gcaaataaaa tcagaagcag gtgtgacaat
     7681 gaatgaaaaa gaagttgaaa gcttagttga aaagcaaggc tattctaatt ctgatatata
     7741 tgcagaatta tactatcaat atcctatttt tttaaacgta aatgaaaaat ataagaaaat
     7801 gaaactaagt tctaagttag tttatatgtt actaaaagat agaaatagac tttcattgaa
     7861 aaataacttg tatgatgaga atcaaaaaat ttttttgata tttgaaatca aaaatctcgt
     7921 agaaatttcg ggaatgtcaa aaaatacaat cttatcagca ctagatgaac ttcaaaaagt
     7981 taaacttctt gtgaaaagaa aaaatggctt caataaaagt aaaatgcaaa tgttcccaaa
     8041 tttttattat ttgttaaagc ctgttctgtg caaagatgat gtttataaaa ttaataagat
     8101 aacccatcaa gaaaatagac aaaaaaactt gatagttcaa aatttgaact atggaacaaa
     8161 tcaatattct gttgatagtt caaaatttga actatgcgac acatcaatga aaacaagaga
     8221 caaaaacaat tttgctgata gttcaaaaaa tgaactagaa ttatataagt cttataaaga
     8281 tagtaaagat attaaagaat cacataatga tgatcttctt gaatcacttt caactaaaaa
     8341 taataaatta gatgaagaat tgatcgaaac atttattgaa gaaaatcttc ttaaacaaat
     8401 atggggagaa agtattgtga attgcttaaa actggctagc aatagtgatt atcgtcaatt
     8461 cgacaactgg tacaaaaaat tcaaatatgc gattagatct gctgaaaaag aacaaaaaat
     8521 tcaactgaaa attatctatg aaatttgtaa taacaagtat tttgtagatc atgttagaga
     8581 acagctatca atgactttac gtgacttgat acgaagagca aaaacagatc atcgtatcaa
     8641 acaaaaagac gattatatct ttgcttctct aaaaaataaa gcgttagaac taattgaatt
     8701 gcaaatcagc gaaggaatag ataagcaata agaatagaat tgagtcaaat gaaatggagg
     8761 ggtatctcca cttcatttga gaactttgaa tataggaggg gttattttga ttaaaaatcg
     8821 tttaatagat caagtttggt gtctagatca aaatacagat agtctcgaat taatcgagac
     8881 tatttgcttc aacactatag ttctcgattt aagagctgaa aatgataatt gtgtaactca
     8941 tgtcataatt aatcaaaaaa tggctcagaa gctctctgag agcctcagaa aatgggctaa
     9001 gggaggtaac gatgaaaata attgaaaaaa agattgccaa taaaaaaata aattggttgg
     9061 ttgttaattt tcttgttctg atagctatga ttatttttac aagtaatatt gctcatgcga
     9121 gtattttcaa ttggtttgat gacacaaaaa gtcaaacaga gtttttgaat aattctcttt
     9181 atagacctta cctaaaaaag tacaatggag atttccttag tcagttcggg atttggctcg
     9241 gatgggctgt ggtaaaaggc atgtttactg tgacagattc gattcaaaat atgattccag
     9301 atgtgctgga tttgttcaat ttcattgaaa gtacagggct aaataatgtt tatcaatcag
     9361 ccgtaaatac aattgtcatt ggattaatga tcctttcatt gatgtttgtt ggttacaaaa
     9421 tgattactgg aaaaggaaca gtggatttaa aatcggttgg aatgaacgta gtgatgtcta
     9481 tagcattaat acttttaatg ccaaccatga tttctagtgg tattcaattt gctaaaacat
     9541 tttataagga ctctactacg attacaaatt cagatgacgg agtcgcttgg tcattgataa
     9601 aacaaggagt aacagattta gcatatatta ataaaacaga tcagtactca agcattgata
     9661 aaacggagga tcgaaataat ttaacacgaa aaaattttca acagacggat ctcacacaag
     9721 tgttaacgga taaagtgatt gataaattgg aaaaagaaaa tccaattgcg gacaatcttc
     9781 gttatgaatt agttgaaaat tctaataatg aatttgttgc tacaaagttt tctgacaact
     9841 tcttatcaac attttctgat agcttgaaat caggctatta ccgataccaa gcaaatctat
     9901 gggggatttc aattgggttg acagcgttag caatcgccta tgtgttcagc gcgtttgtga
     9961 tcattacagc aatactagaa cttgcattta aacgtgtgtt aggtgttctt gtttttgcaa
    10021 cagatattga gacaggacag cgttcaaaag ttgttctatc agatattcta caatgttact
    10081 taactgttgg gtttcaagga tttgggttat caatgtttgc tatgtttatc aattttctga
    10141 actcaggaca aggtatctca acaaatattt ttataaaaac aattgcttat atctgtgccg
    10201 tttttgtttt aatcaaaggc agtggaacag tcatgagata ctttggtgtt gatattggac
    10261 tcaaagaagg ctatgggcaa cttgcttctg cttttggaat gggcgcaatg ctgtttagaa
    10321 aaggatcaaa tggatttaat cgtgctaaag gaagcggaga aggagaagat cgaaaaccag
    10381 aaaagaattt cggcgaaact ctatcaaaaa aagctggcaa aactggaaga gctttgggat
    10441 atgcccatga acgtggatta tccggtttag cttcagatgg agctacaatg gctagtgaaa
    10501 gagcaacaaa accatttaag agtatgcgtg atatagctaa tgataccaag aataagttta
    10561 aagaaggttt agatgatggt acagtgtccg ctattaataa aaatagcaaa cctatgttag
    10621 ctaaaaataa agaagatgaa actggaaaat atgctgattc cgtgccaaca cgtctttcag
    10681 atagaaaaga tggtgctaaa gttgaaaatg ccgatagaat tatgtctagt tctgaacgta
    10741 tgcgtgaagc aatgaaaaat aatgctgaat cgaataataa tcctgcaagc gcaattcagc
    10801 aaaaagtcca acaagatatt gaagaacgta aaaatgctat gcacggtcaa gctaagtctg
    10861 ctgaagaatt aattaatcag aagcgtcatg aagcgaaata cacgcctgaa gcaatgaatc
    10921 gcgaggaaat aatgttaagg aaacgtgtag aagggcggac aggcgctaat attgacggaa
    10981 aagaagcgtt gaccaaagaa agaattcaag aagctaaaaa ttcaaataca ggattagaaa
    11041 aattagtcaa agaaaatcca caaaattcta caagtagtca tggtggccga tcagtagatg
    11101 tccgagaaaa tattcaaggt tcactgaatg gtcatgttgg acggaatgtt gatgtaagag
    11161 agaatttaca aagttcttca aatgctcaag gtactaagac aattgatgtt cgagaaaatc
    11221 tgcaaagtag cagtacaagt caaccaaaaa cagtagatgt tcgagaaaat gtacaaaatt
    11281 ctacaagtag tcaaggattc aaaacagtag atgttcggga gaacattcaa aaagatagtg
    11341 gagaaatgaa agaaaaaaca caaaaaatca atatcgttga agacagaaag tcagcgaaaa
    11401 aatttgattc aaatcatgaa acagtgatta ttgatagtga aatccgtgaa aatgataagg
    11461 gatcaaaatc aagacgaaga ttcacttatg aagacaatga gttattcaga gatacactta
    11521 atgatcctaa tccacttttc gataatttat taagaaataa aaggggggga ttgtcatgca
    11581 attaattcta aagattagta cgcatgattt cttagaactt gacgaattat gtgaatcagt
    11641 aaagaacgca acaaatgaaa aaatcacggt cactaattat attgaactga tgattcaaga
    11701 agaattaaag atgaaaaatg aaatagagag caatttcaaa tgttgctctc tagaaaaaaa
    11761 tgtgagggga taatcaatgg atgataaaca aaaaatgtac gaaaaaaatc gcaaacatag
    11821 tgaggcctta aattttcgtg tcgataaaaa gacttatctt gaactgacat tgattgcaaa
    11881 acaaagggga atttctagag cagacgtttg ccgtgagcgg ttaaagggac tcaaatatga
    11941 accgccgttg ttagctgaag atgatagggt agttttaacc aaacagttaa atcaaattgg
    12001 taacaatttg aatcaagcgg taaaggcatt aaatatcatt gctaaatatt ttagagaaga
    12061 atctgaagat aaaaaagaaa agagcctaca ttttagtttt gatgctagcc gttacaacat
    12121 ttttaaagat gaacttgcga atagcatagc aaaaaagttg atgattagtt atccagatga
    12181 catttttttg gagtccaatc ggagtgcccc ctcttttttt aaattatcag aagtagaaaa
    12241 agaatatttc gaatattgga tagaaaagca aactagaccg ggtacgaaag aagagtattc
    12301 ccaaaaagtt gatcggaatt taattcactc aattcagatt attgcaagtt taaaagatga
    12361 ggtgaaacaa ctttgggagc tactataaca tcgaaaggac gcaagaaaaa tttatcctcg
    12421 ctattacaat atgcagctaa tccttcaaaa aaagaaaaat gtgttgcagt ctcaggaata
    12481 aattgtagtg atgatagtga ggaagcactg caagaaatga atttagtacg taccaagatg
    12541 aataaatcta aagatatagc acaagcgttt catgttattc attcgtttga taagagtact
    12601 tctaaagagt taagtattga taaaatgcac gaaatagctg tcgaatttgc agagaaagct
    12661 tttccaaatt cgcaaatcat tgttgcaagt cacaatgata aagatcattt tcatagtcat
    12721 cttgtcatta ataatattaa catggaaaca tgtaaaaggt tgcgtattga ccctaaagat
    12781 ttagaactaa tgcgaaaaat taacgatcaa gtcctcaatg aacatggtct tgaatcagtg
    12841 aataatgagt actatgaaaa cttagaaaag agaaccaatc tttattcaaa cgatccttct
    12901 aagatgaaat atggaaaaat taattatcaa gagtttgtgc aaaatgcgat cgaagcaacg
    12961 ttggaaaaat gcgaagtgaa ttcttttgaa gatttttcgg atcatttggc aaaagaatat
    13021 aacattgaag tttatcaatt ttcaaaaaca aataacaaac ttggctatgt tctttacaaa
    13081 caaggtgtaa atttctatga gcgtagaggt gagttaatta ctttaggaag agataaacaa
    13141 tctagaaaag aaaaaagtca gtatgtcgaa cgtactttta gtgcaagaaa gttagggaaa
    13201 agatattcat ttgaatctgt ttctgaacaa cttgaaaaga atttagaaga atcacatata
    13261 aaaaattttt ttaatatgga aagagagcaa gttatgtcgc taattagtgg agtaaattac
    13321 aaaactggtg agttaaatgt accgtttgtg gaattagatt ccatcgcaca aaagcaattt
    13381 agcgaccgtg aaggcgatga aaaattcatt aaatatgatg acttcttgcg agaggtagac
    13441 aagcattttg taaatacaat gtctttagaa gatgatcaag aatacacgat taaacttcat
    13501 acggatgtga atcctcaaac tttacgtagt gcgaaaagta aaacaatttc tattaaaaag
    13561 actgatcaga aagagttatt tctaccggca aagggttttg aaaattgttc tcatacacct
    13621 tctgctaaac agattcacta tcaaatcagt cgcataatga atgacgatgt aaaaatgtat
    13681 cgtgctaaaa aggattatga attcacacaa caaatgattg aaaatcagca aaaaaggcaa
    13741 caaaattttg aaatggaatt ctgaatgggc ttgttagtgg actttccagt tttttgccta
    13801 tgaagagttg cttggaaaga agcagttttt aggacatacg ccagctaccc atctacttgc
    13861 cagtcaatcc gccccgctca cgctaggcta ctttctggca agtcagatgg cgggtaaatc
    13921 tctgagggag caagctccct acagactccc tcccaaaaaa agaaaggtgg aagaaaaaaa
    13981 tgaactatcc atattttaaa gtctcggctt cagaagaaac taaagaaata ttcaacaatt
    14041 tttacaacca aaacaaagga atttttggtt caaaggcaaa tatgtttcgt gttatggttt
    14101 caaatttacc agtgttagct agtccatcaa ataataaatt taatgatcct gaaagcatta
    14161 aatttgaaca aaaaatttca gaactagaat caatgataag taatgaagta attgaaaagc
    14221 tggatgacat tgatcaaaag ttatcgtatt ctctaaaaaa caaatacaaa acggaggaga
    14281 aaaaagatgt ttaaagttta cttcccgttt cagtggctcg ttaaaggaat tcttttagtg
    14341 ctactaggat tgattctttt tggaagttat ctaacaatta aagccagaca ttttccagaa
    14401 gaaaagccaa taaaaattgt aacaaaagat ttaaaaatag gtgaaactta tcaggcagat
    14461 ggggttgaac taacatttaa aaatattgaa gtgaccgaaa aaagaaatga atttgcacaa
    14521 catgatcgtg tattacaagt gacctataca cttataaatg atacagaaaa tccgatacgt
    14581 ccacaacaat ggtcgattga aaataaggat ggtgaagaac tttatgagta tgatatgata
    14641 ttggataatc cagagtatat tgaaagtggc aaagaagaaa cagtaaatta ctattatgaa
    14701 ttaccgattg aaaggcagga ctaccaaatc gtagtacgta gagagaatgg ttacatagtt
    14761 gggttgccat ttactttata agttttattt tgttagtagt ttttaaggta atatcagttt
    14821 tgtgattttt gaaaatggaa ctgggagaat ggctgaggaa aataaagttg ttccgtttga
    14881 aacattagtg ataaataagg aagagtttga gcaacttttt cttgattttt ttattcaata
    14941 tgacatgatt tatgatttta gttcgtcact agatttattt gaattagaag cagaaataat
    15001 agaaaacagt cgagagaaga atggtaaaat cattatttca gtagaaaaat tcaatgaatt
    15061 attctcacaa acatttgaaa tagatccaga ctattatcaa ccacaagaag tttttcgaga
    15121 gtttagaaat aagattattg gttttagtca aactacaaaa tgaaagctta ataaagcaag
    15181 tgttgataga attattcctc aacgcttgct ttattttatg ggcacttcat aatagaggta
    15241 tagagaagag aggtattcat tttggatact attactccaa caaacttcaa agaaaatata
    15301 ggtaaagtgt tgcaagaagt agttcattca aattctgaaa tagaaattac tagggattct
    15361 aaaaatggat tgaacgatgg cgtcattatg atttctaaga gaaaatggga gttgttacaa
    15421 gaagaacttt atttacaacg aacgggtaca tgggcttatg tatctgattt a
//
LOCUS       DAFBVQ010000059        15162 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.062, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000059 DAFBVQ010000000
VERSION     DAFBVQ010000059.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15162)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15162)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15162
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.062"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            278..787
                     /locus_tag="LLC22_002180"
     CDS             278..787
                     /locus_tag="LLC22_002180"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305710.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5435436.1"
                     /translation="MVQGIERGVYVVDKIQFNQVIEEFIKVNNLMTHIQKRPIRITND
                     LKLSTSMIHLIDVIGNYPETSITELADRLGVTKGAVSQQIPTLEKMNLISISQKKGNK
                     KTKLVSLTKYGRKVYESHNYLHEELYSSINEALESFSPDQISTIKQILEKVSYTINEY
                     QVSLTRKED"
     gene            880..2042
                     /locus_tag="LLC22_002181"
     CDS             join(880..1156,1156..2042)
                     /locus_tag="LLC22_002181"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBK5435437.1"
                     /translation="MSRRQRRTYSKEFKQQVVDLYLAGKPRAEIIRDYELTTSAFDKW
                     VKQAQTTGSFQEKDNLIPEQVELIALRKKNKQLEMENDILKQAALILGPKRQVIDTNK
                     HKYSISAMCKVLNISCQTYYYQAKPVEDESELEELVQEEFIRNRKAYGTRKLKQCLAN
                     LGLQVSQRRIGRMMKQRGLRSTYTLAHFKFHSSTCNEAKTANILDGTFLQEKSLEAIV
                     TDLTYVRVGKKWQYICLILDLFNREIIGYSCGEKKDATLVKEAFAKIPYSLNNVQLFH
                     TDRGKEFDNQTIDEILWAFNITRSLSKKGCPYDNAVAESTYKSVKVEFVHQYRFETLA
                     NLRLELFDYVHWWNTIRLHGTLGYETPISFRQQRLAQRILDNELGCDTGGEAP"
     gene            2322..3302
                     /locus_tag="LLC22_002182"
     CDS             2322..3302
                     /locus_tag="LLC22_002182"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179831.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5435438.1"
                     /translation="MKKIGIREVAKEANVSPTTVSRVLNDRGYLSEETKRKVFDAMKK
                     LEYYPNELARALFKNETYTVGLIFPTITNPFHAELIQDIEFELSSRGYKVLLCNSLNN
                     PTKEKEYLTMLRKNQVDGIIVGTHNKDIADYDIPGLPIVAIDRSLGENTVTVSCDNYR
                     GGELATQLLVNHGCQNILCIRGDSKIKLPANSRTLAYKDVLNKFMLEPLVLEVPFVKE
                     INEKNEIIKTYLETHPNIDGVFAGDDLLASLAINNLGSSGKRVPKEVKVIGFDGAQQT
                     LIYNPELSTIQQPIDQISKVAVKKLLNMIKGEKETDELSLPVKLIKKNTA"
     gene            3424..4842
                     /locus_tag="LLC22_002183"
     CDS             3424..4842
                     /locus_tag="LLC22_002183"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="family 43 glycosylhydrolase"
                     /protein_id="HBK5435439.1"
                     /translation="MEKLLIKSNNHQLYYQPKDVWVGDVMPYGKEGKFFIYHQRDTRN
                     PVPFGEPFGWALATTKDFVHFEDFGESLLRGDDNERDQFIYAGSVFEANGKVHAFYTG
                     YNREFLAQGKTSQVLLHAESDDFVHWEKSETALELEPQEGYDIRNWRDPFVVWDDEKE
                     EYLLILGARKGQDKHLQTGRLVEFTSKDLTNWEFKGDFWAPGLYTMFEMPELFKIGDW
                     WYLVYSEYSDGNKILYRMSQSLEGPWIKPKDEAFDGRAYYAGRTAYDGKRRVLFGWVP
                     TKDQENDKNNYLWGGTLVPHEVYQKEDFSLGVKPIDEVWNAFINLHDIADVEIETADT
                     REEVTLVKNSGTLFNLETTISFDENLSDFSLRLYKNLETDESYEYRFNLDEGRLTFDK
                     NPCYPWFQYMDKGLIRPISLKPNQSYKLKVIVDDNIMTLYIDGIALNARVHGCFGQAI
                     TITATNGSMTAINTKFSNEIKK"
     gene            4913..6382
                     /locus_tag="LLC22_002184"
     CDS             4913..6382
                     /locus_tag="LLC22_002184"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179833.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5435440.1"
                     /translation="MDYKKIAEDVLENVGGKENISSATHCITRLRLILKDKSKANMEM
                     LEEIEGAKGVLFNSGQLQVIFGTGIIEKVYKEFVELTGAKEVSVSEMKDEGVNNSGNR
                     LQRAFKVFSDIFIPIIPAFIGAAMVLGIRSLITTPGMFGMDGSFADHNVFLNDLSKFL
                     GIIATTFDYLPVLVMYSATKRFGGNPILGLLVGFVMIHPGLANRNDFVMGTIKPDYWH
                     LFGLSIPAVAFQGGVFPAILTSWFLAKVEKITNKYSPQVLAYILVPTVTIVLANFALF
                     LVFGPLGNFIGNVLGGIIDFLYMKMGAFGAFVFAGALQPLVVTGTQHAIQGIEANLVA
                     TTGFNYIQPIWSVSIIAQGGGCIGMYLLFKKKSKDRDIAISSFIPTLVGITEPAIFAV
                     NLKYSIVPFVCSFIGAGFGGAFMKIFDVKAIGQGLTVLPGLTIANPVLPYIFGNLIAF
                     ILPIIFILAYDKYKVFIPEAKHRKFAEKTDSKKLPVQVK"
     gene            6392..6859
                     /locus_tag="LLC22_002185"
     CDS             6392..6859
                     /locus_tag="LLC22_002185"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289220.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5435441.1"
                     /translation="MLNFFRKNEISVVAPATGVFEKLEKLSDPVFSKGMMGQGFAIDA
                     KNETIVSPIDGFVSSIFPTKHALGIKTKSGIEILVHVGIDTVELNGEGFDIKVQEGQK
                     VKAGDILMTINFVVFEKNHKTKDVIVVFPDYQDEIFIPKLEEVKQGQELFVLG"
     gene            6895..7767
                     /locus_tag="LLC22_002186"
     CDS             6895..7767
                     /locus_tag="LLC22_002186"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289219.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5435442.1"
                     /translation="MVFGAIEAGGTKFVCAIGDKDLNIFEKVSFPTTTPKETMNLVLD
                     FFNHHKDDLEGIGVGSFGPIDIHCESKTYGFITSTPKLAWQDFDFIGSLKKQLNIPTA
                     WTTDVNASCYGEYVSGNGRGLSSVVYYTVGTGIGGGAIQNGNFIEGFSHPEMGHMLVK
                     RHNKDNFSGTCPFHGDCLEGLAAGPAIERRSGKKGQEVTENDVTWEIEAYYIAQCAYN
                     TTLMLSPDVIIFGGGVMKQKHLKKKVQDKFIELINGYVAIPDVDNYIMTPKLLDNSGI
                     VGCLALARDVKEKS"
     gene            7848..10382
                     /locus_tag="LLC22_002187"
     CDS             7848..10382
                     /locus_tag="LLC22_002187"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353084.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma 54-interacting transcriptional regulator"
                     /protein_id="HBK5435443.1"
                     /translation="MKKKMKDEVLEYIKNNLKYYDFSAQDIAMKFCIKRNVASHYLNQ
                     LFSDGKLLKNDSVRPVMFKYNQQKPKDCFSKFIGADISLKSTIDKCKATVMYPPNGLP
                     LIIKGNSGVGKSFLASLIYQYALDRKVIHNDAKFVVVNCADYANNPELLSAVLFGYKK
                     GAFTGAEKDTAGMLSSANGGYLFLDEVHNLSAENQEKLFLLMDSQKYRKLGESVQWEY
                     ANVRLILATTEDKNTSLLATFRRRIPAEITLPDYNNRSTSEKIQLLFEFLKDEAITID
                     SKIFCSIELFTDLLSKTFEGNVGELRNEIKLLCAEGYLGNKRKSSIYLGDKLDSGFWI
                     DPEISIDLKKMFLKSLSEIDLIELFQNHISIEESMSQLRDRILKECAGSSEYNYLESD
                     EFIALRNYVVNKISPIIDSTGLCLLDEFLADISLFIMFIDVIEETSRNFLLSKFRKFR
                     MKNDKQKLLANEIWSSLEVEESKQELLLKWILFLVKKFYVKIPETHCLIVMHGKITAS
                     AIARETNKLLNTYVYEAFDMPIEGETSDLINLINNFCKSIDTTNGLILLVDMGSLEQM
                     YEKIESNVIGDLVILNNVSTALAIECGIQVCQKKPISHFYQMDFDSFQVKVQYYKGLS
                     QKKNVIVSCLSGEGISEKVKDILKRYLDNQVEILIFDFNALKKIAKEKDTMIFKNTIC
                     VLSTTEFYIQGIDCLNLENLINGNQTLEKLNKYMDSDSCEFCLNELVKLFTIEGASTK
                     LRFLDSKKVFNEIEKVLYLYEKYYDVKIPSFLRINLFLHLSGMIERIMIGDGITNEHL
                     KEGAQLFDTFLNVSKDFFSEIKDIYCIEIPKGEYELIYTIFEQTIF"
     gene            10538..11311
                     /locus_tag="LLC22_002188"
     CDS             10538..11311
                     /locus_tag="LLC22_002188"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5435444.1"
                     /translation="MAFWQTFLVVLYGFFINWDKEGPKIGTSQPVVAGFLTGLIMGDI
                     QTGLYIGGTLQLMTLGITSFGGASVPDYQTAALIGTYLAISTNQDASIGITLAIPVAM
                     LIVQLDVLKWSTNIFFQQKAEKFAQKEDYQKLEWMQYLASINTSFVSGIPVLLTVILG
                     PTLVGSAINYIPEWVTGGLKVAGGLLPAVGIGMLLKYLPTKDYFAYLLVGFVLAVYFQ
                     IPILGISLLGAAIALIVYKNRSNNTQVAPAATGGFDEDE"
     gene            11304..12095
                     /locus_tag="LLC22_002189"
     CDS             11304..12095
                     /locus_tag="LLC22_002189"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289216.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5435445.1"
                     /translation="MNKKLTKIDKQVIFRWILNGATSLNYEKMEGLGYAYSMLPFIKD
                     TYKDDPEGMKQSVLAHLQFFNTTPYTAPYIIGMNVGIEKEEKNKSLEAVSALKTGLMG
                     PLAGIGDSVFVVIPWTIFGAIAANMALEGSFVGIILWILASILLRITAYPLYLAGKES
                     GASLLTQIETKLKSITDAVSILGLMVVGALIATVVKVNVGFEFKQGDLTMTGNEIFDQ
                     VMPGLLPACVVAIVYYLLGRKVKPVYVILLILVVSIALRALNILK"
     gene            12105..12596
                     /locus_tag="LLC22_002190"
     CDS             12105..12596
                     /locus_tag="LLC22_002190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289215.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5435446.1"
                     /translation="MDEKMKGIIHVRIDDRMIHGQVATQWTNQLSANRIMVINNEVAN
                     DDVKKAVVRLAAPPNVRTSIITREVAVKNILSGKYEGQKVLIVAVSPIDVKFLIDNGL
                     PITSVNVGNLSRRNGTERIRPTINITEEEREAFKELISDGVEVTVIQTPRDSKEFLKD
                     FIY"
     gene            12614..13024
                     /locus_tag="LLC22_002191"
     CDS             12614..13024
                     /locus_tag="LLC22_002191"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289214.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5435447.1"
                     /translation="MEFIITSHGNIAIGFVDTLKMFFGDNLNCHVVTLGDAGIEEFRE
                     NIEKIVSQVKNQEVMVFADLIGGTPFNEFAKRSEVFQNGFQLLGGMNLGILIEAVNLR
                     LQGKKSDDIIENLRNMNTIACLADMQRHTNEEDE"
     gene            13028..14428
                     /locus_tag="LLC22_002192"
     CDS             13028..14428
                     /locus_tag="LLC22_002192"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-fructofuranosidase"
                     /protein_id="HBK5435448.1"
                     /translation="MQKIFYKPKDFWFGDCMPFYKDGTFYLFHQRDTRNPKPLTDPFG
                     WSLVTTTDFVKFEEYGEVIHRGGNDDIDQYIYAGSIVQGINEYLALYTGHNRKAKLDG
                     KTSEVLMIASSKDLIHWKKDGEAAKLVPQEGYDKNDWRDPFAIFDQDHGKYVLILGAR
                     KPASKKKPTGRLVYFESEDLKDWNFKGDYWANNEFNMIEMPDIFEIDGTWYLLFSEYC
                     EDKKTKYRVGAGLFSDWKSPVDEAFDGKAYYAARTVGTNETGRFLTGWVATKEGENDQ
                     NNWDWGGALVPHQIIQKTDKTLGVKLPEKIIENFKEITPFSSFKLEKEFGKKERVIVP
                     KIEDYFLFETTLTITSLTKEFALKLFVDSDTQEGYEFRISLINNQLTFGKTPNYPWPQ
                     MFDKGLQRPLFLEIGKEYELKLIVDDTIAVLYIDNVALSTRMYDKVGTALSMTVTEGA
                     IKVDKLDYSINYECGF"
     gene            14451..14825
                     /locus_tag="LLC22_002193"
     CDS             14451..14825
                     /locus_tag="LLC22_002193"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016179839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="VOC family protein"
                     /protein_id="HBK5435449.1"
                     /translation="MKLNGLQHIGIPTKDFGASKIFYESLGFSLINEEMNVGSKVGFF
                     ELNGTIIEIWEDKTTECRGAIDHLALDTDDIDEVFNSIQDLGYELLDKNIMELPFWEN
                     GIRYFNFYGPNHEIIEISQMKK"
BASE COUNT         5269 a         2126 c         3038 g         4729 t
ORIGIN      
        1 ttttttattt gtctcgctta attatacaaa cggcgtgata aaaaacgaga aatgaattat
       61 aggtttagac ctttatcatt tctcgtttta ttttattgta tcaaggctct atcataagtg
      121 gtaaaatcta cttttaaatc acatgtaatc attgataagt ccagtgtttt agcggataat
      181 cagcttttta tttatttttt cttataaatt tgataaatag aaattagtat agccctaaac
      241 aaattatttg tgttttattg tttagggcta tactatattg gtacaaggaa tagaaagagg
      301 tgtttatgtg gttgataaaa ttcagtttaa tcaagttata gaagaattca tcaaagtaaa
      361 taatttaatg acccatattc aaaaacgacc aatcagaata actaatgatc taaaactcag
      421 tacgagtatg attcatttga ttgatgtgat tggaaattat cctgaaacta gtattacgga
      481 attagctgat cgattaggcg ttaccaaagg agctgtatcc caacagattc ccactttaga
      541 gaaaatgaat cttataagca tttctcaaaa aaaaggaaat aagaaaacta aacttgtatc
      601 gttaacaaaa tatggtcgaa aggtgtacga atcacataat tatttacatg aagagcttta
      661 tagctcaata aatgaagcgt tagaatcatt ctcaccagac caaatttcaa ccattaaaca
      721 gattctagaa aaagtatctt atacaatcaa tgaatatcaa gtaagtctga caagaaagga
      781 agattgacat gaaaaaaatg atttttgaat cggctacact agactagaca gaaaaaataa
      841 ggtgtgtaaa ataaatgaaa acacactgga ggaattttta tgtcaagacg tcaacgtaga
      901 acctattcaa aagaattcaa acaacaagtc gtcgatcttt atctcgcagg aaagccccga
      961 gctgaaatca ttcgagatta tgagctgact acctcggcct ttgataagtg ggtcaagcaa
     1021 gcgcaaacta ctggctcgtt tcaggaaaaa gataacttga tccctgaaca agtagaacta
     1081 attgcattac gaaagaaaaa taaacagctt gaaatggaga atgacatttt aaagcaagcg
     1141 gcgctgatat tgggacgaaa agacaagtaa ttgataccaa taagcacaaa tactcaatat
     1201 cagcgatgtg taaagtgtta aacatctctt gccaaaccta ttattatcaa gccaaaccag
     1261 ttgaagatga atcagaactg gaagaactcg ttcaagaaga atttattcgc aatcgaaaag
     1321 cttatggtac caggaagctg aagcagtgct tggccaatct aggtcttcaa gtgagtcaac
     1381 gcagaatcgg ccgtatgatg aaacagcgtg gcttgcgttc aacatacaca ttggctcatt
     1441 tcaaattcca ttcttctact tgtaacgaag ccaagaccgc caatattcta gacggaacct
     1501 tcctacagga aaagtcatta gaagcgattg taaccgacct tacctatgtt cgtgttggga
     1561 agaaatggca gtatatctgc ctgattcttg atttgtttaa tcgagaaatc atcggctatt
     1621 catgcgggga gaagaaagat gcgacgttag tcaaggaagc ttttgcaaag attccgtact
     1681 cgttgaataa tgtacaactt tttcacacgg atcgtggaaa agaattcgat aaccagacga
     1741 ttgacgaaat tttatgggcc tttaatatca cgcgttcctt aagcaaaaaa ggctgcccct
     1801 atgataacgc cgttgcagaa tccacctata aatctgtcaa agtagaattc gttcatcaat
     1861 accgctttga gacattggct aatttgcgat tagagctatt tgattacgtc cattggtgga
     1921 ataccatccg gctgcacggc acgttaggct atgagacacc gatcagtttt cgacagcaga
     1981 gattggcgca gcgaatcctt gataatgagc tcggatgtga taccggtggc gaggcacctt
     2041 aattatttga atgagcttct gccttagaga atcagattcg aggaggctcg ttgtcaaggg
     2101 cagtcggaac accagcagca agcttacgca ataccttata atttttgtca aaaaaagtgt
     2161 tgccattcca catatatctt taaacagcta ttgccagata aaaataaatg atattatata
     2221 tataaatact tatccgaaaa ggggaatgag agagtcaagg ttcttggaat gtcgaatagt
     2281 cgagtaggta gattttctat ctacaacctt gttgtttaaa aatgaaaaaa attggaatta
     2341 gagaagttgc gaaagaggca aatgtttctc ctacgactgt gtcgagggta ttgaatgatc
     2401 gtggatattt gagtgaggaa acaaaaagaa aagtttttga tgccatgaaa aaattagaat
     2461 actatcctaa tgaactggcg agagcacttt ttaaaaacga aacatatacc gtaggtttga
     2521 tttttcctac aattactaat ccatttcacg ctgagttaat tcaagatatc gagttcgagc
     2581 tttccagcag gggatataaa gtgttgctgt gcaatagctt aaacaatcca acaaaagaaa
     2641 aagagtactt gacgatgttg agaaagaatc aggttgatgg aattatagta ggaacgcaca
     2701 ataaagatat tgcggattat gatattccag ggctacctat tgtagcgatt gatagaagtc
     2761 ttggtgaaaa tacagttaca gtatcttgtg ataattacag gggtggggaa ttagctactc
     2821 aactacttgt aaatcatggc tgtcagaata tactgtgtat tcggggagat agtaagataa
     2881 agctacccgc gaatagtagg actttagcat ataaagatgt tttgaataaa ttcatgctgg
     2941 aaccgttagt cctagaagta ccatttgtaa aagaaatcaa tgaaaaaaat gaaataatta
     3001 agacatatct ggaaactcat ccaaatattg acggggtttt tgcaggagat gatttattgg
     3061 cttctttggc gattaacaac ttaggaagtt cgggcaaaag agttccaaaa gaggttaaag
     3121 tgattggatt tgatggagct caacaaacat tgatttataa tccagaatta tcaactattc
     3181 aacagcctat agatcaaata tctaaagtag cagtaaaaaa attattgaat atgattaagg
     3241 gcgaaaagga gacggatgaa ctttcacttc cagtaaagct cataaaaaaa aatacagcat
     3301 aagttaaatc ggcgaaaaat tccttcgtcg atttaaaaat atttttatga aacgggttga
     3361 catatgaaac gggttgacat atattagttg tgaagataaa aaccttttca ctggaggaag
     3421 aaaatggaga aattattaat taaaagcaat aatcatcaac tttactacca acctaaggat
     3481 gtttgggtcg gagatgttat gccttacggg aaagaaggaa aattctttat ttatcatcaa
     3541 cgtgatacta gaaatccagt tccttttgga gaaccgtttg gctgggcttt agcaactacg
     3601 aaagattttg ttcattttga agactttggg gaatctcttt taagagggga tgacaatgag
     3661 agagaccagt ttatctacgc tggttctgta tttgaggcaa atggaaaggt tcacgcattt
     3721 tatacagggt ataatcgtga attcttagcg cagggaaaga catctcaagt gttgcttcat
     3781 gctgagagtg atgattttgt tcattgggaa aaatcagaaa cagcattgga gttagaacca
     3841 caagaagggt atgatattcg aaactggaga gatccatttg tcgtttggga tgatgaaaaa
     3901 gaagaatatt tgctaatttt aggggcgcga aagggtcagg ataaacatct acaaaccgga
     3961 cgtttagtgg aatttacatc aaaagattta actaattggg aattcaaagg tgatttttgg
     4021 gctccgggat tgtataccat gtttgaaatg ccagaacttt tcaagattgg tgactggtgg
     4081 tatcttgtct attcagaata ctcagatgga aataaaatac tctatcgaat gagtcaaagt
     4141 ttggaaggtc cttggattaa gcctaaagat gaagcttttg atggacgggc ttattatgca
     4201 ggtagaacag cttatgatgg aaaacgtcga gtcctatttg gatgggtacc aacaaaagat
     4261 caagaaaatg ataaaaacaa ttatttatgg ggaggtactt tggttcctca tgaagtctat
     4321 caaaaagagg atttttcact tggggtaaaa cccatagacg aagtgtggaa tgcattcata
     4381 aatttacatg atattgccga tgtagagata gaaacagcag acacaagaga agaagtaacg
     4441 cttgtcaaaa atagtggaac tttgtttaat ttagaaacaa caatttcatt tgatgagaat
     4501 cttagtgact tttcactgag attatataaa aaccttgaga cagatgaatc ttacgaatat
     4561 cgcttcaatt tagatgaggg gcgtcttaca tttgataaaa acccttgtta cccttggttt
     4621 caatatatgg ataaaggact tattagacct atatctttaa agcctaacca atcttataaa
     4681 ctaaaagtga ttgttgatga caatataatg acactttata ttgatggaat cgctcttaac
     4741 gctcgtgtac atggttgttt tggtcaagca attactatta cagcaacaaa tggatcaatg
     4801 actgcaataa ataccaagtt ttcaaatgaa ataaagaaat aataaacgtc aatcatgtgg
     4861 caggtctgaa aatcaaacat gacctgtcac atttaaaagg gaggataaat gaatggacta
     4921 caaaaaaatt gccgaagatg tattggaaaa cgttggagga aaagagaata tctcaagcgc
     4981 tacacactgc attactcgtt tacgtttaat tcttaaagac aaaagcaaag cgaatatgga
     5041 aatgcttgag gaaatagaag gtgcaaaagg tgttcttttc aatagtggac agttacaagt
     5101 aattttcgga acaggtataa ttgaaaaggt ttacaaagag ttcgttgaat tgacaggagc
     5161 taaggaagta tccgtttctg aaatgaaaga cgaaggagtc aataattcag gaaatagact
     5221 tcaacgagct tttaaagttt tctcggatat ctttattccg atcattccag cttttattgg
     5281 ggcagcaatg gttttaggaa ttcgttcgtt gattaccact cctggaatgt ttggaatgga
     5341 tggctcattc gctgatcaca atgtattcct aaatgattta tccaaatttc tgggtattat
     5401 tgcaaccaca tttgattatt taccagtttt agttatgtat tctgcaacaa aacgttttgg
     5461 cggaaaccct attttaggat tacttgtagg atttgttatg attcatccag gactagccaa
     5521 tcggaatgat ttcgtcatgg gaactataaa gcctgattat tggcatttat ttggattaag
     5581 cattccagca gttgcgtttc aagggggtgt ttttccagca attttgactt cttggttttt
     5641 agcaaaagtt gagaaaatta caaataaata ttctcctcaa gtacttgctt acattttagt
     5701 cccaactgtg acaattgttc ttgccaactt tgcactattt ttagtgtttg gtccattggg
     5761 gaattttatc ggtaatgttt taggtggaat cattgatttc ctatatatga agatgggtgc
     5821 ctttggtgct tttgtttttg caggcgcgtt acaaccatta gttgtaacag gaacacaaca
     5881 tgctattcaa ggtattgagg caaacttagt cgcaacaact ggattcaatt atatccaacc
     5941 tatttggtca gtttcaatta ttgcccaagg tggcggttgt attggtatgt atttactctt
     6001 taagaaaaaa tctaaagata gagatattgc gatttcaagc tttattccaa cactggtagg
     6061 tattactgaa ccggctatct ttgctgttaa tttgaaatat tcaatcgttc cttttgtttg
     6121 ctcgtttatt ggtgctggtt ttggtggagc atttatgaaa atttttgatg taaaagccat
     6181 tggacaagga ttgactgtat tgccaggtct gactattgct aatccagttc ttccttatat
     6241 atttggtaat ctcatagcat tcattttacc aatcattttt attctcgctt atgataaata
     6301 taaagtgttt atccctgaag ctaaacaccg taaatttgca gaaaaaactg actcaaaaaa
     6361 attgccagtt caagtaaagt gagatgagag catgttaaat ttttttagaa aaaatgaaat
     6421 aagcgttgta gcacctgcaa ccggtgtttt tgaaaaactg gagaaattaa gtgatccagt
     6481 cttttcaaaa ggaatgatgg gacaaggatt tgcaattgat gcaaaaaacg aaacgattgt
     6541 atctccaatc gatggttttg tttcaagtat ttttcctaca aaacatgcct taggaataaa
     6601 aacaaaatca ggaattgaga tacttgttca tgtaggaata gatacagttg agctaaatgg
     6661 tgagggattt gatattaaag ttcaagaagg acaaaaagtt aaggctgggg atattcttat
     6721 gaccattaat tttgtagttt ttgaaaagaa tcacaagact aaagatgtca ttgttgtttt
     6781 tccagactac caagacgaaa ttttcattcc gaaacttgaa gaagtaaaac aaggacaaga
     6841 attgtttgtt cttggctaat gataagtaat taataataga atcgaggaaa atgtatggtt
     6901 tttggggcta ttgaagctgg tggaacaaaa tttgtttgtg ccattggaga taaagatttg
     6961 aacatatttg aaaaagtcag ctttcccacg actacaccca aagaaacaat gaatttagtt
     7021 ttagattttt ttaatcatca taaagatgat ttagaaggta tcggagtggg atcgttcggt
     7081 cctattgata ttcattgtga atctaaaacg tatggcttca ttacatcaac gccaaaactt
     7141 gcttggcagg attttgattt tattggaagt ttaaaaaagc aacttaatat tccaactgct
     7201 tggacgactg atgtaaatgc ctcttgctat ggtgaatatg tttctggaaa tggcagaggc
     7261 ctttcaagtg ttgtttacta taccgtagga acgggcatag gaggtggcgc tatccaaaac
     7321 ggaaacttca ttgaaggttt tagtcatcca gaaatgggac atatgcttgt aaaacgacac
     7381 aataaagaca acttttctgg gacatgtcca ttccacggag actgtttaga gggcttagct
     7441 gctggtccgg caatcgaaag aagatcaggg aaaaagggac aagaagtgac tgaaaatgac
     7501 gttacttggg aaatagaagc ttattacatt gctcagtgtg catataatac aacattgatg
     7561 ttatcacctg atgtcattat atttggtggc ggagtaatga aacaaaaaca cttaaaaaag
     7621 aaagtacaag ataagtttat tgagttgatc aacggatatg tcgctattcc cgatgttgac
     7681 aattatatta tgacaccaaa attgttagat aattctggta ttgtaggttg tttagcttta
     7741 gcaagagacg ttaaagaaaa atcttaattt ggaaaaaaga tcgtctcgac tatttgtttg
     7801 gttgatgcga tctttttttc aattagtaat tgaagggacg cctaaaagtg aaaaaaaaaa
     7861 tgaaagatga agtattagag tatatcaaaa ataatttaaa gtattacgat ttttctgctc
     7921 aagatattgc aatgaaattt tgtattaaaa gaaatgtcgc ttcccactat ttgaatcagt
     7981 tattttcaga tggaaaatta ctaaagaatg attctgttag accagtaatg ttcaagtata
     8041 atcaacaaaa gccaaaagac tgcttttcta agtttattgg agcagacata tctttgaaat
     8101 ccactataga taaatgcaaa gctactgtaa tgtatccccc taatggcctc ccattaataa
     8161 taaaaggaaa cagtggcgtt ggaaaaagtt ttttagcaag tttgatctat cagtatgctc
     8221 ttgatagaaa agtaattcat aatgacgcaa aatttgttgt tgtgaattgt gcagattatg
     8281 caaataatcc agagctattg tcagcagttt tatttggata taaaaaagga gcctttactg
     8341 gggctgaaaa agatactgca gggatgctat cttctgctaa tggaggatac ctttttttag
     8401 atgaggttca caatctaagt gcagaaaacc aagagaaatt gtttcttctt atggattctc
     8461 aaaagtatcg taaacttggt gaaagtgtgc aatgggagta tgcaaatgtt cgccttatct
     8521 tagccacaac agaagataaa aatacctctt tgttagcaac ttttagaaga cgcatcccag
     8581 ctgaaatcac tctgccagat tacaataata gaagtacatc tgaaaaaatt caattattat
     8641 ttgaatttct taaagatgaa gcaattacga ttgattcaaa aatattttgt tcgattgaac
     8701 tttttactga tcttttatcg aaaacatttg aaggaaatgt tggagaattg aggaatgaaa
     8761 tcaagcttct ttgtgcagaa ggttatttag gaaataagag aaagtcttca atttatttag
     8821 gggacaaact agacagcggt ttttggatag atccagaaat tagtatagat ttaaaaaaaa
     8881 tgtttcttaa atcactttct gaaattgatt tgattgaact ttttcaaaat cacatttcaa
     8941 ttgaagaaag catgagtcaa ttaagagata gaatacttaa agagtgtgca ggttcttctg
     9001 agtataatta tttagaaagt gacgaattta tagcattaag aaactatgtt gttaataaaa
     9061 tatcaccaat tattgattcg acaggtctat gtttattaga tgaattcttg gcggatatca
     9121 gtctatttat aatgtttatt gatgtaattg aagaaacatc aagaaatttt ttgctgtcta
     9181 agttcagaaa atttcgtatg aaaaatgata aacaaaaatt attggcaaat gagatttgga
     9241 gtagtttaga agtcgaagaa agtaaacaag aacttttgtt gaaatggata ctttttcttg
     9301 taaagaagtt ctatgtgaaa ataccagaaa cccattgtct gatagttatg cacggtaaaa
     9361 taacagcttc tgcgatcgca agggaaacaa ataagttgct gaatacatat gtttatgagg
     9421 ctttcgatat gccaattgaa ggtgagacta gtgacttaat taacctaatc aacaattttt
     9481 gtaaaagtat agatacgacg aatggactca ttctgctagt tgatatggga tcattggaac
     9541 aaatgtatga aaaaattgaa tccaatgtaa taggtgattt ggtaatttta aacaatgttt
     9601 ctacagcttt agcgattgaa tgtgggattc aagtttgcca aaaaaagcca attagtcatt
     9661 tttaccagat ggattttgat tcgtttcaag ttaaagttca gtattataaa ggattatcac
     9721 aaaagaaaaa tgtaatagta tcttgtctct ctggtgaggg gatttctgaa aaagttaagg
     9781 atattttaaa acggtatctc gataatcaag tggagatttt gatttttgat tttaacgcat
     9841 taaagaaaat agcaaaggaa aaagatacta tgatttttaa gaatacaatt tgtgttcttt
     9901 caaccactga attttacatt caaggaatcg attgtttaaa tttagaaaat ctaattaatg
     9961 ggaatcaaac cttagaaaaa ttaaataagt atatggactc ggatagctgt gagttctgct
    10021 taaatgaatt agttaaactc tttactattg aaggcgctag tactaagctt cgctttttag
    10081 attccaaaaa agtattcaat gagatagaaa aagtactata tttgtatgaa aaatattacg
    10141 atgtcaaaat cccaagtttt ctgagaatta atctatttct acatctttct ggaatgattg
    10201 aacgaattat gattggtgat ggaataacaa atgaacattt gaaagaggga gcgcaactat
    10261 ttgatacttt tttaaatgta tcaaaagatt ttttttcaga aatcaaagat atttactgta
    10321 ttgaaatacc caaaggagag tatgagttaa tctatacaat ttttgagcag actattttct
    10381 aaatagcata ctagcgtcta aaaaaatgaa agggtgtcca aagtatattt agacgctcat
    10441 ttaattaata tttactgtat tttcccgctt tattggataa tgttagttgg cacagtaatt
    10501 gcttatataa aagtataaga agaaaggaga gaacaaaatg gcgttttggc aaacattttt
    10561 agttgtgttg tatggatttt tcattaactg ggataaggaa gggcccaaaa tcggaacctc
    10621 ccaacctgtc gttgcaggtt tcttgaccgg acttattatg ggagatattc aaactggact
    10681 ttatatcggt gggactttgc aattaatgac actaggtatt actagttttg gtggtgcatc
    10741 agtaccggat tatcaaacag cagcattgat cggtacttat ttagcaatct caactaacca
    10801 ggatgcttct ataggaataa ctttagcaat accggtagca atgttaattg tacaactaga
    10861 tgttctaaag tggtcaacaa acattttttt tcaacaaaag gcagaaaaat tcgcacaaaa
    10921 agaagattat caaaaattag agtggatgca atatttggca tcaattaata caagctttgt
    10981 atctggaatt cctgttttgt taactgtgat attaggccca acgttagtgg gaagtgcaat
    11041 caattatatt cctgaatggg ttaccggtgg tttaaaggta gcagggggac tattacctgc
    11101 tgttgggata ggaatgctac ttaaatattt acctacaaaa gattactttg cctatttgtt
    11161 agttggtttc gttttggcag tttatttcca aataccaatt ttagggattt cgttacttgg
    11221 cgctgcaatc gcactaatcg tatataaaaa tagatcaaat aatactcaag tagcaccagc
    11281 tgcaacagga ggttttgacg aagatgaata agaaactgac aaaaatcgac aaacaagtaa
    11341 ttttccggtg gattctcaat ggtgcaactt cattaaatta tgaaaaaatg gaagggttgg
    11401 gttatgcgta ttctatgctt ccttttatca aggacacata taaagatgat cctgaaggaa
    11461 tgaaacaatc cgttttagct cacttacaat tttttaacac tacgccgtat acagcgcctt
    11521 acattattgg tatgaatgtt ggaattgaaa aagaagaaaa aaataagtct ttggaagcag
    11581 taagtgctct gaaaacaggt ctaatgggtc ctttagcggg aattggagat agtgtatttg
    11641 tagttattcc atggactatt tttggagcaa ttgcagctaa tatggcattg gaaggtagtt
    11701 ttgttggaat tattttgtgg atactggcat caattttatt aaggattact gcttatcctt
    11761 tataccttgc tgggaaagaa tcgggtgcga gcctactaac tcaaattgaa acaaaattaa
    11821 agtctattac tgatgcagta tcaattttag ggttaatggt ggtcggtgca ctcattgcca
    11881 cagttgtaaa agtgaatgtt ggctttgaat ttaaacaagg cgacttaaca atgaccggaa
    11941 atgaaatctt tgatcaagtt atgcctggtt tattacctgc atgtgtagta gcaattgtgt
    12001 attatttgtt aggacgaaag gttaaaccag tttatgtaat tctattaatc ttagtagttt
    12061 ctattgcgtt aagagcgtta aatattttga agtaggtgtt gaatatggat gaaaaaatga
    12121 aaggtattat acatgttcgt attgatgatc gaatgattca tggacaagta gcaacacaat
    12181 ggacaaatca attgagtgct aacagaatta tggttattaa taatgaagta gccaatgatg
    12241 acgtaaaaaa agctgtagtt cgcctcgctg caccacctaa tgttagaact tcaataatta
    12301 caagggaagt agcagttaaa aatattcttt ctggtaaata tgaaggacaa aaagttctta
    12361 ttgttgcagt ttctccaatc gatgttaaat ttttgattga taacggttta ccaataacaa
    12421 gtgtaaacgt aggaaattta tcaagaagga atggaacaga acgcatccgt ccgacgataa
    12481 atattactga agaagagaga gaggctttta aagaactaat tagtgatgga gttgaagtga
    12541 cagtgataca aactcctaga gattcaaaag aatttttaaa ggattttatt tattaagaac
    12601 agaggatgag tggatggagt ttataattac atctcatgga aatattgcca ttggatttgt
    12661 agatacatta aaaatgtttt ttggcgataa tttaaattgt catgtggtaa cacttggaga
    12721 tgcaggcatt gaagaattcc gtgaaaacat tgaaaaaata gtttctcaag taaaaaatca
    12781 agaagttatg gtatttgctg acttgattgg tggaacacct ttcaacgaat ttgctaaaag
    12841 aagtgaagta tttcaaaatg ggtttcaact tcttggtggc atgaatttag gaattttgat
    12901 tgaggctgtc aatttgagat tacaaggaaa aaaaagcgat gatatcatcg aaaatctaag
    12961 aaatatgaat acaattgcgt gtcttgcaga tatgcaaaga catactaacg aagaggatga
    13021 gtgataaatg caaaaaattt tttacaagcc taaagatttt tggtttgggg attgcatgcc
    13081 tttttataaa gatggaactt tttatctatt tcatcaacga gatacgagaa atcctaaacc
    13141 tttaactgat ccttttgggt ggtcactagt tacaaccact gattttgtga aatttgaaga
    13201 atacggggaa gtaattcatc gtggtggcaa cgatgacatt gatcaataca tttacgctgg
    13261 aagtattgtc caaggaatca atgagtattt agctttgtat actggacata atcgcaaagc
    13321 taagttggat ggaaaaactt cagaagtgtt aatgattgca agttctaaag atttaattca
    13381 ttggaaaaag gatggcgaag cagcaaaact tgttcctcaa gaaggatatg ataagaatga
    13441 ttggcgcgat ccttttgcaa tttttgatca agatcatgga aaatacgttt tgatactagg
    13501 agctagaaaa ccagcaagta agaaaaagcc gacggggaga ttggtctatt ttgaatccga
    13561 agatttaaaa gattggaatt tcaaaggaga ctactgggct aataatgaat ttaacatgat
    13621 tgaaatgcct gatatatttg aaattgatgg aacgtggtat ttactttttt cagagtattg
    13681 tgaagataaa aagactaaat atcgagtcgg agcaggatta ttttcagatt ggaaatcacc
    13741 agtagacgaa gctttcgacg gaaaagccta ttatgcagca agaacagtcg gaactaatga
    13801 aactggccgt tttctaactg gctgggtggc aacaaaagaa ggggagaacg atcaaaataa
    13861 ctgggattgg ggcggtgcac ttgttccaca tcaaattatt caaaagacag acaaaactct
    13921 tggtgttaaa ctgcctgaaa aaataattga gaattttaaa gaaatcactc cattttcaag
    13981 ttttaagtta gagaaagaat ttggaaaaaa agaaagagta attgttccta aaatcgaaga
    14041 ttattttcta tttgaaacaa ctttgactat tacatcgtta acaaaggagt ttgctttaaa
    14101 attatttgta gatagtgata ctcaagaagg atacgaattt cgtatttcat tgattaataa
    14161 tcagcttact ttcggaaaaa ctccgaacta tccttggcct caaatgtttg ataaggggct
    14221 gcaacgacca ctatttttgg aaataggcaa agaatatgaa ctaaagttaa ttgttgatga
    14281 tacgatagct gttttatata ttgataatgt tgctttaagt actagaatgt atgataaagt
    14341 cggaacagca ttaagtatga ctgttacgga gggagcaatc aaggtagata aactagacta
    14401 ttcaataaat tatgaatgtg gattttaaaa caattgaagg gatgatgtaa gtgaaattaa
    14461 atggtttaca acatattgga attccaacaa aagattttgg agcttcaaaa atcttttatg
    14521 aatccttagg gtttagtctg attaatgaag aaatgaatgt gggaagtaaa gtcggctttt
    14581 tcgagttgaa tggaacgata atagaaatat gggaagataa aactactgag tgtagaggag
    14641 ccattgatca tctagcatta gatacggatg acatagatga ggtattcaat tcaattcaag
    14701 atttaggata tgaattatta gataaaaata ttatggaatt accgttctgg gaaaatggaa
    14761 tccgttactt taatttctac ggaccaaatc atgagattat agagataagc caaatgaaga
    14821 aataaataga taacgaagtg ctctaagttg gtatgaacga aaagtacttc attttttggt
    14881 atcagcattt caatagttta atgagaattt actatttcaa attaattcaa agtgacagta
    14941 ttttttactt atttggtttc aaattttgta atccttccta tttattggaa tacactccac
    15001 attttgtata caagtcatat catgttttag caaagctctt accaagcaaa gttataatga
    15061 tgttttccaa agtttgatct ttcgatggag gctaacacat attttttgca ggacagccaa
    15121 aattagatgt atagaataga gtctgtgagg cgtatagaca gt
//
LOCUS       DAFBVQ010000060        15141 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.063, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000060 DAFBVQ010000000
VERSION     DAFBVQ010000060.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 15141)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 15141)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..15141
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.063"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..344
                     /locus_tag="LLC22_002194"
     CDS             <1..344
                     /locus_tag="LLC22_002194"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435450.1"
                     /translation="NIKTSTKLICKLFKLDKISNIDDVKSKILTRKVSEPVKLTAQDK
                     KNGIVLYGDDAKYNYNWDTSSEAEVLSIPTTDTSGEKVTFKINFITAISKLEYGKQKK
                     RDNNDQYLPKK"
     gene            425..1045
                     /locus_tag="LLC22_002195"
     CDS             425..1045
                     /locus_tag="LLC22_002195"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321568.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435451.1"
                     /translation="MNINRVIKLIGAKNINKVRSEFIFPEDFFNWFFYQFSECKRLLG
                     ENYYLKGIGGFMGNVADEQNIIKGISEQTSELTVTKAFISNGESLKNVTARIRKENEV
                     DIVFGIDHECNSVIYVTQSANLILFENGCKDDFMVVYLYDILIPKLRSLYMSSESIFV
                     SEQKGSFSKKIGIEVIESIMCHNHITLEELEILIGQKNNNTKIQVS"
     gene            1746..2030
                     /locus_tag="LLC22_002196"
     CDS             1746..2030
                     /locus_tag="LLC22_002196"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287509.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435452.1"
                     /translation="MFSFAFYMVWLQREVPTHIQGRLMSTITTITMVASPLGLALFGA
                     LFDWQTTQPRLRDSLIFLEIQLENLHFLYTFLAAFFIPVNYTSLINKKEG"
     gene            2033..2950
                     /locus_tag="LLC22_002197"
     CDS             2033..2950
                     /locus_tag="LLC22_002197"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5435453.1"
                     /translation="MDFGNETVLKATGITKKYGAAKALDKVSIEIKRGMIYGLIGENG
                     AGKSTFMRTIMGLISIDEGSIELFGTTDLQAARRRMGQSIETPALYPELTARDNLRIQ
                     AANGGVSDREIEDLLKMMRLENTGKKKAKNFSLGMRQRLAIANALITNPEFLILDEPT
                     NGMDPAGMAEMREIIQRLVKERGITVLLSSHLLDELSQIATHYGILHEGHLIKELSKE
                     ELAQESRQFIKIDTSATEQAVTVLDSLGYRDYFVQSSRVIQLFEGIDQVAAINQALVE
                     AKVPVDGIHLVGQKLEDYFLQLTGGNPHV"
     gene            2943..3725
                     /locus_tag="LLC22_002198"
     CDS             2943..3725
                     /locus_tag="LLC22_002198"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287500.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435454.1"
                     /translation="MFNLLTAEKIKVWKSRKMWVSLGLMVVLPLFYSWNEWYMHTKYG
                     NELNQATDTVINGATGILMVEKMAAWILLAFAAFACFYIGEEFQNGTIRNTLSLGRNR
                     MTYYVSKLLVTLLITTLGVVLITGLAMIAYTLAFGFGEVEGIKNYGNYVLKVFPVLLL
                     LILATLSVPVALTFITRSTSVSLLLSFLYIMGTAFVPGVFAKIKGLEFLTEWFTETWL
                     MYTDFAQQATYSQAPKMILVSLVTIVVSSALGMFIFQKSDIK"
     gene            3726..4406
                     /locus_tag="LLC22_002199"
     CDS             3726..4406
                     /locus_tag="LLC22_002199"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287499.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5435455.1"
                     /translation="MFLLETILIIEDDEAVHSLLEEVLEQRYKLLDAYSGTEGKLLLS
                     TYPVDLILLDLMLPGLSGEALLAEIRQTSNVPIIVLSAKSDQRDKVSLLAAGADDYVT
                     KPFDIEELLLRIGIQLRHQTSVQVKDLSQRIYYKEILLDKESRDVNVNGVAVHLTGRE
                     FDLLKLFLEHPKKVFSRANLYETVWQEPYFDSEKTVNMHISNLRGKLAKAHAVYIHTV
                     WGVGFRFD"
     gene            4399..5295
                     /locus_tag="LLC22_002200"
     CDS             4399..5295
                     /locus_tag="LLC22_002200"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314301.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5435456.1"
                     /translation="MIKWLLLLVVIFMGSFIFFLQREIKRLTKKIATLSERQEYGGRL
                     SVEFREKNLMDLVDALNTWVDENEQKGQAFQEMEENIRLSIVGLSHDLRTPLTAINGY
                     VQLLEQVEDTEKREKYLTIIKQSVARLLSMTDQFYDLARIETKQKEMDLHTLSFSKEV
                     EEVFFSFYEQFSEKNIEVAFAEHSINTTVLADPLMLLRVLQNIIQNLLRYADGQAKVT
                     FSKEDSFIRLTVANPIKPGAQTSVEKVFQRFYTENTSRTNTESSGIGLYLSKKLVEGM
                     GGEMTARLDGGIFSISVKLRRV"
     gene            5490..7139
                     /locus_tag="LLC22_002201"
     CDS             5490..7139
                     /locus_tag="LLC22_002201"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA mismatch repair protein MutS"
                     /protein_id="HBK5435457.1"
                     /translation="MGQREFIVLIIIAVVILLVVLDIFSRLKVKETVRSNWGKIPYQP
                     RFDKEESLKDAWLTEKKFRSWDSEIDDLTWYDLDMFEVFEGINSTYSSVGSEALYQRL
                     RSFDFGEDYQLEKLIAFYQENPQLRERIQYQFARLGKKDHNFAKQYLADGKSKKIGRV
                     GLFIFLGLLPLVGVGLLLLGQVLGIYLAIGGLVFNTVYYLVKKQTLETELNSMSYLVS
                     TISAANQLAKMTTPLQKELKQQTKPLRDIPKLGFSFRMKSGSEAELIFEYVNIMFMLP
                     FISYHFVLTKLEKHSTEAIKLWELLGELEVAAAVLNYRTYMPITCRPEFTEGGVTAKD
                     IYHPLLKEAVVNPVNWQKNTLVTGSNASGKSTYVKSIAISCILAQTIQTAIAEQFTLQ
                     PGHVLTSMAIEDDLFEGDSYFVSEIKSIKRLLDQVTSKERCYCFVDEILKGTNTIERI
                     ASSASVVRWLAEYPSLAFVATHDIELTEILKNYCENVHFEEQVTEGKGISFDFKLKEG
                     PSRTRNAIALLKVLNYPKSIVEQAQKESLLFDEQRQWYPFD"
     gene            7733..8668
                     /locus_tag="LLC22_002202"
     CDS             7733..8668
                     /locus_tag="LLC22_002202"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376359.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435458.1"
                     /translation="MANALEINNLKKIYGSGVEALRGIDLSVKEGDFYALLGPNGAGK
                     STTIGIITSLVNKTSGKVNVFGYDLDKDLVRAKQQIGLVPQEFNFNPFETVQQIVVNQ
                     AGYYGVSRKEAMKRSEKYLKQSNLWEKRNVRARMLSGGMKRRLMIARALMHEPRLLIL
                     DEPTAGVDIELRREMWEFLRELNENGTTIILTTHYLEEAEMLCRNIGIIQSGELIENT
                     SMKELLSKLQFETFIFDLAPYDTKPVIEGYACTFEDEQTIAVEVERNQGVNGIFDQLT
                     RQGIKVLSMRNKSNRLEELFLKITEENNHTEEKNV"
     gene            8661..9431
                     /locus_tag="LLC22_002203"
     CDS             8661..9431
                     /locus_tag="LLC22_002203"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435459.1"
                     /translation="MFNLYFTALKSLAIKETNRYLRIWVQTLVPPVITTSLYFVIFGK
                     MIGGRIGDMGGFSYMEFIVPGLIMMSAITSSYANVSSSFFSQKFQKNIEEILVAPVPT
                     HVIIWGFVIGGVGRSILVGSLVTIISLFFVPLHVYSWFMVIITLLMTAILFSLAGLLN
                     GIFAQSYDDVSIVPTFVLQPLTYLGGVFYAISMLPPFWQAVSKVNPIVYMISGFRYGF
                     LGTIDVPVATSMIVLVLFIVVLYAVTWYLINKGRGLRS"
     gene            9847..10830
                     /locus_tag="LLC22_002204"
     CDS             9847..10830
                     /locus_tag="LLC22_002204"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA-dihydrouridine synthase"
                     /protein_id="HBK5435460.1"
                     /translation="MTTNFWKELPKPFFVLAPMEDVTDVVFRHVVKHAAAPDVFFTEF
                     TNSDSFCHPDGKDSVRGRLTFTEDEQPMVAHIWGDKPEFFREMSIAMAEMGFQGIDIN
                     MGCPVPNVAERGKGSGLILRPEVAAQLIEAAKAGGLPVSVKTRIGYTEMSEMEEWISH
                     LLHQDIANLSVHLRTRKEMSKVDAHWEVIPKIIALRDQIAPQTLITINGDIPDRQTGE
                     ELAEKYGVDGIMIGRGIFKNPYAFEKDPREHTEKELIGLLRLQLDLQDHYSEIIPRSI
                     TGLHRFFKIYIKGFPGANDLRVQLMNTKSTDEVREILETFEKEHPTLFSEQ"
     gene            11277..12311
                     /locus_tag="LLC22_002205"
     CDS             11277..12311
                     /locus_tag="LLC22_002205"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329811.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zinc-binding alcohol dehydrogenase family
                     protein"
                     /protein_id="HBK5435461.1"
                     /translation="MSEKELMKVVGFYEGLPIDDPKSFIDEKEQIPVPSSRDLLVKVN
                     AVSVNPVDTKLRQDNGIRNALRILGFDGVGKVVAVGDEVQKFSVGDRVFYAGTTRAGS
                     NQEYQLVDERIVALAPKNLSDEEAAALPLTSLTAYELLFEKFGLTPEENANRGKKILV
                     INGSGGVGSILNQLAHWAGLEVYATASPKNFEWLKKTGVDYPIDYHHDLSKSFRELGI
                     DQVEYVAVLFDITRYFDQIKHLVRPFGHVGTIVGIKEPLDIGVWKNQSISFDWEYMFA
                     KTDYNYEIETQGEALAHIAALANEGIIRSTLSKVYSDGMNAKNLKQATKDVETGHMLG
                     KVVVSGPFNG"
     gene            complement(12400..12723)
                     /locus_tag="LLC22_002206"
     CDS             complement(12400..12723)
                     /locus_tag="LLC22_002206"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlD domain-containing protein"
                     /protein_id="HBK5435462.1"
                     /translation="MPSFEFTLLTILGCTLATWLSRVLPFVLLKKFDLPQPLLEYLSF
                     VPIVIMSALWFSSLFTQNIGHLPQINLENALASVPTLLAAILSKSLLVIVLAGILSLS
                     LIRLL"
     gene            complement(12710..13417)
                     /locus_tag="LLC22_002207"
     CDS             complement(12710..13417)
                     /locus_tag="LLC22_002207"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326602.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AzlC family ABC transporter permease"
                     /protein_id="HBK5435463.1"
                     /translation="MDEKLDIKTAIKDTLPTVFGYIGIGLAFGIVGKAAGFHPLVVTL
                     MSLLVYAGSAQFITVSMLASHSPLLSIVFSTFLVNSRMILMSMTIAPYFKKNRLLQNL
                     LIGTLLTDESFALGMNKLNYTGQKLNFRWMNTANWISYLTWVGSSLVGALLGNFITDP
                     KKFGLDFAIVAMFIGLLYLQVISDRNTSKRLQLILIGLTLILVYVGLIFIPSNLVIVV
                     VTLIGCGLGVWIKHAFF"
     gene            13503..13844
                     /locus_tag="LLC22_002208"
     CDS             13503..13844
                     /locus_tag="LLC22_002208"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874852.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="xylulose kinase"
                     /protein_id="HBK5435464.1"
                     /translation="MVGLKRKELAGRRFTRIVSVGGGAKNLAWLQIQADIFDATVYCL
                     SVEEGPALGATMIAALGLGWFDTPESCCQNFIQYTDAVEPLLQNVEKYHKIYQQCRKI
                     YPATKEICHDL"
     gene            complement(14015..14863)
                     /locus_tag="LLC22_002209"
     CDS             complement(14015..14863)
                     /locus_tag="LLC22_002209"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435465.1"
                     /translation="MNNWLEYFPENVLERGYSYHLHGFVRHLNYTSKYLSATVSGTED
                     YKVVITWDEKTNMTCDCLYAIEGKKCKHMAAVLFAYEERPIKKSNYSLSELSSLVSSA
                     SSSLVRELLTEILIEHPHFIERFKVKMPFHAINYSDKLTTIIHKYDHIIKKNKNRKTA
                     KFIMEMRKFIQEAVESLIQQNAYLPAFELINEVIATLETFYWEPEDERTLLLIEDCYY
                     LWKELLAEAPHAEKRQMFSWFVCQVDHTDASYSKRYSIKILKEDFREKEFSNQKKKID
                     KKLKKR"
BASE COUNT         4855 a         2579 c         3199 g         4508 t
ORIGIN      
        1 caaatataaa aactagtacg aaattaattt gtaaattatt taagcttgat aaaataagca
       61 atatcgatga tgtaaagtcc aagatattaa caagaaaagt aagcgaacca gtaaagctaa
      121 cggcacaaga taaaaaaaat ggaattgttc tttatggtga tgatgcaaag tataactata
      181 attgggatac ctcctcagaa gctgaggtat taagtattcc tactaccgat acttcagggg
      241 aaaaagtcac ctttaaaata aattttataa cggcaatttc taagttggag tatgggaagc
      301 aaaaaaagag agataacaat gatcaatatc tacctaaaaa ataacgaatt aatgatgcat
      361 atgttaaagt tgtttttttg aattaaacaa ctcaatttat tcagttatat gttcatcgca
      421 gcaagtgaac attaatcgag ttataaaatt aataggagct aaaaatataa ataaagttcg
      481 atcagaattt atttttccag aagatttttt taactggttt ttttatcaat tcagtgaatg
      541 caagcgactc ttaggtgaga attattactt aaaaggaatc ggcggattta tggggaatgt
      601 ggctgatgaa caaaatatta taaaaggaat atctgaacaa acatcagagc ttacagtaac
      661 taaagcattt ataagtaatg gtgaaagttt gaaaaatgta actgcgcgaa ttagaaaaga
      721 aaatgaagta gacattgttt ttggaattga ccatgaatgt aattcagtga tatatgtaac
      781 acaatcagca aatttaattc tttttgagaa tggttgcaag gacgatttta tggtggtcta
      841 tttgtacgat atactaattc caaaacttcg ttccttatat atgtcttctg aaagtatttt
      901 tgtgagtgaa caaaagggat ctttctcgaa aaaaataggt attgaagtaa ttgaatcgat
      961 tatgtgtcat aatcatatta cgctagaaga attagaaatt ttgatagggc aaaaaaataa
     1021 taacacgaaa atacaagttt cttagaaatc attttttatt gagatatcta gataaatgat
     1081 ttattcttca atcaaccaac tcgccaagct gaggtaatgt tttgaggtaa tgataacata
     1141 caacttttta taccctagta aaactctata aacaaagact tattaatttc gcatgaaata
     1201 cattcctgta aaatgcaata aaatagagtt ttgtttaacc aggtcttaag aaagcccgta
     1261 aagcttcaca gttctcaaaa cgttaattgc gattatcgtt cgagttcacg agttacgaga
     1321 atcgtactgg gcgaagcaat gctgagcgca gttaccttaa tcctaacttt tctggcactt
     1381 tccacaattt ggaaagtgcc ttttttgtgt ttttagctat gttaataggt aggattcttg
     1441 gtctataata tcattcgatc tataaacaaa cgggaaaaag ataaagtatc atcaaacaat
     1501 attatttatc cgcttctgag gttgtgacag aagtggtcag cttcaagaaa taagaaggaa
     1561 tttacaaaaa ttgcttctca tgtttgataa atattgtgac ttgtgaccga ggagttggca
     1621 ggagaacacc gtttattcgg aagaagggat tgtgaaaagt cttttgtcat aacctcttat
     1681 ttggtagcta attgtaaatc ccaaacggca tgtattattt ttcataagtc cgtttttaag
     1741 gattaatgtt ttcttttgct ttttatatgg tctggcttca gcgagaagtt ccaacgcata
     1801 tacaaggacg tctgatgtca acgataacaa cgattaccat ggtggccagt ccacttggat
     1861 tagcactgtt tggtgcgctc tttgattggc agacaactca accacgtctg cgagacagtc
     1921 tgatttttct tgaaattcaa ttggaaaatt tacactttct ttatacattt ctggctgctt
     1981 tctttatacc cgtcaactat acttcactta tcaataagaa agaaggataa gtatggattt
     2041 tggaaatgaa acggtcttga aagcaactgg tataaccaaa aaatacggtg ctgccaaagc
     2101 attagataaa gtatcgatcg aaatcaaacg tggaatgatc tatggtttga ttggggagaa
     2161 tggagcgggt aagtctacct ttatgagaac tattatgggt ttgatctcga ttgatgaagg
     2221 ttcgatcgaa ttatttggaa cgacggattt gcaggcagca agacgacgta tgggtcaatc
     2281 gattgaaacc cctgctcttt atccagaatt aactgcaaga gataacctac gtatccaagc
     2341 agcgaacggc ggtgtgtcgg atagagaaat cgaagacctg ctgaaaatga tgcgattgga
     2401 aaatacaggg aaaaagaaag caaagaattt ctctttaggt atgcgccagc gtttagctat
     2461 tgcaaatgca ctgatcacga atccagaatt tttgattttg gatgaaccga cgaatgggat
     2521 ggatccagca gggatggcag aaatgcgaga aatcatccaa cgtttggtaa aagaacgggg
     2581 catcaccgtc ttgctttcta gccacttgct agatgaattg tcacagatcg ccactcacta
     2641 cggtattttg catgaaggac acttgatcaa agaattatcg aaagaagaat tggcacaaga
     2701 atctcgtcaa tttataaaaa ttgacacttc ggcgacggaa caagcagtaa cggttctcga
     2761 ctctcttggt tatagggatt attttgtcca atctagccgt gttatccagc tttttgaagg
     2821 aattgaccaa gtagcagcca tcaatcaagc attggtagag gcaaaagttc ctgtggatgg
     2881 tatccaccta gttgggcaaa aactggaaga ttatttctta caattaactg gaggcaatcc
     2941 acatgtttaa tctattaact gctgaaaaaa taaaagtatg gaagagccgt aaaatgtggg
     3001 tctcactagg actgatggtc gtacttccgc ttttttattc ttggaacgaa tggtatatgc
     3061 atacaaaata cggcaatgaa ttaaaccaag caacggatac agtcatcaac ggtgcaacag
     3121 ggattttaat ggtggaaaaa atggctgcat ggattcttct ggctttcgca gcatttgcgt
     3181 gcttttatat tggggaagaa tttcaaaacg gtacgattcg caatacgtta tctttaggac
     3241 ggaatcgaat gacttattat gtgtcgaaac ttctcgttac gcttttgatc acaacacttg
     3301 gcgtggtttt gattacgggg ctagccatga ttgcttacac acttgctttc ggatttggtg
     3361 aagttgaggg aatcaaaaac tatggaaatt atgttctaaa agtatttcct gtattgcttc
     3421 tgctgatatt agcgacatta tctgttccag tggctttgac attcatcact agaagtacca
     3481 gtgtcagttt gcttctttct tttctttata tcatgggaac ggccttcgtt cccggtgttt
     3541 tcgcaaaaat caaaggcttg gaatttctaa cggagtggtt tacggaaacg tggctcatgt
     3601 atacggactt tgcgcaacaa gcaacttatt cgcaagcacc gaaaatgatt ctggtcagtc
     3661 tagtaacaat cgtggtatca tcagctctag gaatgtttat tttccaaaaa tctgacatta
     3721 agtaggtgtt cctgctggaa actattttga ttatcgaaga cgatgaagct gttcattctt
     3781 tactggagga ggttcttgaa cagagataca aacttcttga tgcttattca ggtacggaag
     3841 gaaaattatt gttaagcaca tatcctgtcg atttgatcct tctagatctc atgcttccag
     3901 ggctttcagg tgaagcattg ttagcagaaa tccgacagac atcgaatgtt ccgatcatcg
     3961 ttctttcagc aaaaagcgat caaagagata aagtttcctt gttggcagca ggagcggatg
     4021 actatgtgac gaaaccattt gatatcgaag aactgttgtt acgaatcggc atccaacttc
     4081 gtcatcagac ttctgtccaa gtaaaagatc tgtcgcaacg catctattac aaggaaatct
     4141 tactggacaa agagtcgagg gatgtaaatg tgaatggtgt ggctgtccat ttgacaggaa
     4201 gagaattcga tctgctgaag ctttttttag aacatccgaa aaaagtattt tcgcgagcaa
     4261 atctttatga aacagtttgg caagaaccat attttgatag tgagaaaaca gtgaatatgc
     4321 atatttccaa tcttcgaggg aaactagcaa aggcacatgc tgtgtatatt catacggtgt
     4381 ggggagtggg gtttagattt gattaagtgg ctgttgcttc tcgttgttat ctttatggga
     4441 agttttattt tcttcctgca aagggaaatc aagagattaa ctaagaaaat cgccactctt
     4501 tctgaacgac aagaatatgg tggtcgtctt tcagtcgaat ttcgagaaaa gaatctaatg
     4561 gacctagtag atgcactgaa tacatgggtg gatgaaaatg aacaaaaagg acaagcattt
     4621 caagaaatgg aagaaaacat cagactatcg atcgtcggcc tttctcatga tctcagaact
     4681 cctttgactg ctattaacgg ttatgtacaa ttactggaac aggtagagga tacggagaaa
     4741 cgggagaagt atttaacgat catcaaacaa tctgttgcaa gattactcag tatgacggat
     4801 cagttttatg atcttgctcg aatagagacg aagcaaaaag aaatggatct ccatacgctt
     4861 tctttttcta aagaggtgga agaagtattt ttctcttttt atgaacaatt ttctgagaaa
     4921 aatatcgagg tagcgttcgc tgaacactcg ataaatacaa ctgtattagc agatccgctc
     4981 atgttgctgc gagtgctgca aaatatcata cagaatttat tgcgttatgc agatggacaa
     5041 gcaaaggtga cattttcaaa agaggattca ttcattcgat taacagtggc caatcctatc
     5101 aaaccaggag cgcaaacctc tgttgaaaaa gtcttccagc gtttttatac cgaaaatacc
     5161 agccgcacaa atacggaatc tagcggaatc gggctttacc tgtcaaaaaa attggtggaa
     5221 ggaatgggag gagagatgac cgctagatta gacgggggca tcttctccat ctccgtcaag
     5281 ttgcggaggg tttaattggc tctaatttac ctgaagtgaa tgacaaaaaa ttgtatctcg
     5341 ttttaaagac atcttctttt ttggaaggtg tttttatttt ggtgtgattg atacgaatta
     5401 ggtaacgaag acagttattt ttgtaccccc ttttcaaata gcgcaacagt gctatactaa
     5461 aactaacaaa tcaaggaacg gagagggata tgggccaaag agaatttatc gttttaatta
     5521 ttattgcagt tgttatttta ttagttgttt tagacatttt ttcacgtttg aaagtaaagg
     5581 aaacagttcg tagtaattgg ggaaaaattc cttatcaacc gagatttgat aaagaagaaa
     5641 gtttgaagga tgcgtggctc acggagaaaa aattccgttc atgggatagt gaaatcgacg
     5701 atcttacttg gtatgacttg gatatgttcg aagtatttga agggatcaac agtacctatt
     5761 ctagtgtagg ttcagaagcg ttgtatcagc gtttacgtag ctttgatttt ggagaagatt
     5821 atcagttaga aaaactaatt gctttttatc aggaaaatcc tcaactgaga gaaagaatcc
     5881 aatatcaatt cgctcgttta ggaaaaaaag atcataattt tgcaaaacaa tatctagcgg
     5941 atggaaaaag taaaaagatt ggacgcgtag gtttatttat ttttcttggc ttgcttccgc
     6001 tggtgggtgt aggtttgctt cttttagggc aagtactagg aatctatcta gcaatcggtg
     6061 gcttagtatt caatacggtc tattatctag tgaagaaaca aacactagaa acagagctga
     6121 atagcatgag ttatttggtt tcaacgattt cagccgccaa tcagttagca aaaatgacga
     6181 caccacttca aaaagagctg aaacagcaaa ctaaaccatt aagagacatc cctaaattag
     6241 gtttttcatt tcgaatgaag agcgggagtg aagcagaatt gatttttgaa tatgtcaaca
     6301 tcatgttcat gctgccattt atctcctatc atttcgttct cactaaatta gaaaagcatt
     6361 caactgaagc catcaagctg tgggaattgc tgggagaatt ggaagttgca gcagccgttt
     6421 tgaattatcg cacctatatg ccgatcactt gccgaccaga gtttactgag ggcggtgtga
     6481 cagcgaaaga tatctatcat ccattgttaa aagaagcggt agttaatcca gtcaactggc
     6541 agaagaatac attagtcacg ggttccaatg catcaggaaa atctacgtat gtcaaaagta
     6601 tagccatcag ctgtattcta gcacagacga tccaaacagc gattgcagaa cagtttaccc
     6661 tgcaacctgg acatgtgttg acttccatgg caatcgaaga tgatttattt gaaggcgaca
     6721 gttattttgt ttcagaaatc aaatcgatca aacgtttgct ggaccaagtg acttccaaag
     6781 aacgctgcta ctgcttcgta gatgagattt taaaaggaac aaatacgatc gaacggattg
     6841 cttcttccgc ttcagtcgtt cggtggcttg cggagtatcc atctttagca tttgtcgcca
     6901 cacatgatat cgaattgaca gagattttaa agaattattg tgagaatgtc cactttgaag
     6961 aacaagtaac agaaggaaaa ggaatcagtt ttgatttcaa attaaaagaa ggaccttcaa
     7021 ggacccgaaa tgcgattgcc ttgctgaaag ttttgaatta tcctaaatcc atagttgaac
     7081 aggcccaaaa agaaagtttg ttgttcgatg aacagcgtca gtggtatccg tttgattaac
     7141 tttatcaaac gaagcatgat gcgtgggtcc aaaaagacga ttatcaaaag aagtacattg
     7201 atgccaaaaa agtggcagaa ttcaatggga acgagtctgc tgtccagatg atcttggaag
     7261 atttagcaaa agacgataca aaataaacca cgctgtcttc cttctagcag cttttatcga
     7321 aaaaacttag catcagcgac gagacgcacg ttccatggca aagttctccg taaaacaaac
     7381 agcgaaaaca gaaattgaaa ataactattt ccattttatt tatttcggtt aaaataaaag
     7441 aaaaaagctt tcgataaaag gacggaggaa agcttaacat gaataaaaaa gacaagaacc
     7501 tcagttataa ggatcttcta tatgtcatcg tagtagttgc tgtcggtact tttatgattt
     7561 taaaagttcc agagttgttt agatagttat tctatcgaag atgatcatga actagaaaac
     7621 acatctcctc tttgttagca ggtgtgtttt tgtgtggaag ccaagttgtt ttttcatctg
     7681 ctgtattcca tgatacaatt aagaatcatg tctataagga gataggaaat aaatggcaaa
     7741 tgcgcttgaa ataaataatt tgaaaaagat ctatggaagt ggggtcgaag cattgcgggg
     7801 aatcgatctt tcggtgaaag aaggagattt ctatgcgcta ttagggccaa atggagctgg
     7861 gaagtctaca acgatcggga ttattacttc tttagtcaat aaaacatctg gaaaagtgaa
     7921 tgtcttcggt tatgatctgg acaaggatct agttcgagca aagcaacaga ttggattggt
     7981 tccacaagag ttcaatttta acccttttga aacggtccag caaatcgtcg tgaatcaagc
     8041 aggctactac ggtgtctctc gcaaagaagc gatgaaacgc agcgaaaaat atttgaagca
     8101 gtccaatctt tgggaaaaga gaaatgtccg tgcacgtatg ctttccgggg gaatgaagcg
     8161 aagactgatg attgctaggg cattgatgca tgaaccacgt ttgctgatct tggatgaacc
     8221 aacagcagga gttgacatcg agttgagacg cgagatgtgg gagtttctac gagaattgaa
     8281 cgaaaatggt acaacgatca ttttgacgac gcattatcta gaagaagctg aaatgctttg
     8341 tcgcaacatc ggaatcatcc aatcgggtga actgatcgag aatacaagta tgaaagagct
     8401 tctgtcaaaa ctgcaatttg aaacatttat ctttgattta gcgccatatg ataccaaacc
     8461 tgtgattgaa ggatatgctt gtacatttga agatgagcag acaatcgctg tcgaagttga
     8521 acgaaatcaa ggggtgaacg gaatcttcga tcagcttaca agacaaggaa tcaaagttct
     8581 ttctatgagg aataagtcga atcgtttaga agaactgttc ttgaaaatca cagaagaaaa
     8641 taatcatacg gaggagaaaa atgtttaatc tttattttac tgcattaaaa agtttagcta
     8701 tcaaggaaac gaaccgctat ttgcgtatat gggtccaaac actggttccg ccagtgatca
     8761 cgacatcctt gtattttgtt attttcggaa aaatgatcgg tgggcggatc ggtgacatgg
     8821 gtggtttttc atatatggaa ttcatcgttc ctggtttgat tatgatgtct gctatcacta
     8881 gttcgtatgc caatgtttct tcgtccttct tctctcaaaa atttcagaaa aatatcgaag
     8941 aaatcttggt agcacctgtt cctacgcatg tgattatttg gggctttgtg attggtggtg
     9001 tgggtcgcag tattctcgtc ggctctctcg taacgatcat ttccttgttc tttgtaccac
     9061 ttcatgtgta ttcatggttc atggtcatca ttacattatt gatgacggca atcttgtttt
     9121 cattagcagg actgctcaac gggatttttg ctcagtctta tgatgatgta tcgatcgtgc
     9181 ctacatttgt cttgcagccg ttaacttatc taggtggcgt tttctatgcc atctctatgt
     9241 taccgccctt ttggcaagct gtttcaaaag tcaatccgat cgtttatatg atctccggtt
     9301 tccgttacgg attccttgga acgatcgatg tgccagtagc aacatcgatg atcgtacttg
     9361 tgttattcat cgttgttttg tacgccgtta cttggtattt gatcaataaa ggaagaggat
     9421 tgagaagtta gaaaagaggt tgtgaaatca gcgttttgac ctgagtatta gagaaacaaa
     9481 cgggaaaata gttcctcata ttttgttgtt ttttgagcga ataccgaggg tcagctgatt
     9541 gaacaccgtt tagtggagag gttgtgaaaa agctgttctg catcaagtaa taagaacagc
     9601 caaacaaaaa tagctcctcc tatttttcgt ttggttggac ttattaccgc agatgcaagc
     9661 ttttgaacac catttattcc ggaaaatgga ctgtgataag atttttgtca cagtcttttt
     9721 tttgctcaat cagaaacatc ttttaagctg ttcactttgc ttcttttttt gtttcctagt
     9781 ataatgacaa tgtttttgag aaagattgcg acttcactgc ttgatagaat ggagagtaac
     9841 aaataaatga ctactaattt ttggaaagag ctgccaaagc ctttttttgt tttagcacca
     9901 atggaagatg taacagatgt tgtatttcgc catgtcgtaa agcatgcagc agcaccggat
     9961 gtcttcttta ctgagtttac aaactcagac agtttctgtc atccagatgg aaaagacagt
    10021 gtacgaggaa gattaacatt tacagaagat gaacagccga tggttgccca tatttgggga
    10081 gacaagccag aattttttag agaaatgagc attgctatgg cagaaatggg cttccaagga
    10141 atcgatatca acatgggctg cccagtccct aatgtagcag aacgtggaaa aggcagtggc
    10201 ttgatccttc gtccagaagt agcggcacaa ttgattgaag cagctaaagc tggcggtttg
    10261 cctgtcagcg tcaagacgcg tatcggctat acggaaatgt ctgagatgga agaatggatc
    10321 agtcacctac ttcatcaaga tatagccaat ctttctgtcc atttgcgtac gcgtaaagag
    10381 atgagtaaag tagatgcaca ttgggaagtc attcctaaaa tcattgcttt acgtgaccaa
    10441 atcgctccac aaacactaat cacgatcaat ggagatatcc ccgatcgcca gacaggagaa
    10501 gaattggccg agaaatatgg cgttgatggc atcatgattg gccgagggat tttcaagaat
    10561 ccttatgcat ttgaaaaaga cccgagggaa catacagaaa aagaactgat cggactactt
    10621 cgtctgcaac tagatctgca agatcattat tcagaaatca tcccgcgttc catcacagga
    10681 ctacatcgtt tctttaaaat ctatatcaaa ggatttccag gagcaaatga cttgcgagtt
    10741 cagttgatga atacgaaatc tactgatgaa gtacgagaga tcttagagac ctttgaaaaa
    10801 gaacatccaa cgcttttcag tgaacaatga tttcttgctt gaacaccgtg aattagaggt
    10861 cgtgaaaaag ctgtcctgta tcaagtaata agaacagcca aacaaaaata gctcttcata
    10921 ttttgtcgtt ttttgagcta ataccgaggg tcagttgatt gaacaccgtt tatatcagag
    10981 gttgtgagcc tgccgtttaa ctctgagtca caaggagcaa tttcaaaaaa cagcttctca
    11041 tgtttgatga atattttgac ttgtgaccga agagttggta ggagaacacc gtttataaga
    11101 ggttgtgaca aaagtcttgt cgcaacctct tttttaacca aaaaagtgca aatagtttac
    11161 tttaagtaag agaataatta tgatgaataa aaaaggtgga acaaatagca tactatatat
    11221 attgaaatga acactgtatg gatgctccaa cttgatgaag ctaaggagga attcgtatgt
    11281 cagaaaagga attaatgaag gtagtcggtt tttatgaagg gttgccgatc gatgatccaa
    11341 aaagctttat tgatgaaaaa gaacagatac ctgtacccag ttcacgggat cttctggtaa
    11401 aagtcaacgc agtatctgtt aatcctgtcg atacgaaact tcgccaagat aacgggataa
    11461 gaaatgcttt acgtatctta ggttttgatg gagtcgggaa agttgttgct gtaggtgacg
    11521 aagtgcaaaa attttctgtc ggcgatcgcg ttttttacgc aggtacaaca agagcaggaa
    11581 gcaatcaaga ataccaacta gttgacgaac gtattgtcgc tcttgcacca aaaaatcttt
    11641 cagatgaaga agctgcagcc ttgccgttga cctcattgac cgcttatgaa ttgttatttg
    11701 aaaaatttgg tctaactcca gaagaaaatg ccaatcgcgg gaaaaaaatc ttagtgatca
    11761 acggatccgg gggcgtcggt tcgattttga atcaactagc gcattgggct ggcctagaag
    11821 tctacgcgac tgcaagtccg aagaattttg aatggctgaa aaaaacaggt gtagactatc
    11881 caatcgatta tcatcacgac ttaagtaaaa gttttcgtga attaggaatc gatcaagtag
    11941 agtatgtcgc tgtattattc gatattaccc gctactttga tcaaatcaag caccttgtcc
    12001 gaccatttgg acatgtggga acgatcgtag ggatcaaaga gccgttagat ataggtgttt
    12061 ggaaaaacca atctatcagc ttcgactggg agtatatgtt cgctaaaaca gactataact
    12121 atgaaatcga aacgcaagga gaagctttag cgcacattgc tgctttagca aatgaaggga
    12181 ttatccgcag tacattgagc aaggtctatt cagatgggat gaatgcgaag aacttgaaac
    12241 aagcaaccaa agacgtagaa acaggacata tgttaggaaa agtcgttgtt agtggtccgt
    12301 tcaacggata agcaagaata cgccgatttt tttcttattt gactttgata aaaacaagag
    12361 cgcatgacag taatttgcca taagctcttg tttttttatt tataataagc gaatcaacga
    12421 aagggaaaga attcctgcca agacgatcac caataagctt tttgaaagaa tagcagctaa
    12481 aagtgtagga actgaagcca aagcattttc gagattgatc tgcggcagat gtccgatatt
    12541 ttgggtaaat agactgctga accataaagc agacataatg acgatcggga caaaacttaa
    12601 atactcaagc aacggttgcg gtaaatcgaa ttttttcagt aagacaaatg gtaggaccct
    12661 agaaagccaa gttgctaaag tacaacctaa aatagtcagc aatgtaaact caaaagaagg
    12721 catgtttgat ccacaccccc aatccgcacc caatcagtgt tacaactaca atcactaagt
    12781 tgcttgggat aaaaatcagt ccgacatata ccagaatcaa agtgagacca atcaggatca
    12841 actgtaatcg tttagaggtg tttctatcag aaatgacttg aagataaagt aacccgataa
    12901 acatagcgac gatggcgaaa tccaaaccaa actttttcgg atcagtaata aaattcccta
    12961 aaagtgcgcc aacaagagaa gaacccaccc acgtcaaata agaaatccaa ttagctgtat
    13021 tcatccaacg aaagtttaac ttttgtccag tatagttcaa tttattcatt cccagtgcga
    13081 aactttcatc tgtcagcaat gtgccaatca gcagattttg aagcagccga tttttcttga
    13141 aataaggagc aatcgtcata ctcatcagaa tcattcggga attgactaga aaggtcgaga
    13201 aaacgatgga aagcaatggg ctgtgactag caagcatgct gactgtgata aattgggcag
    13261 aaccagcata gaccagcagg gacatcaacg tgacgactag tggatgaaat ccggcagctt
    13321 tcccaacgat accaaatgca agtccaatac cgatataacc gaaaacggta ggtaacgtgt
    13381 ctttgatcgc agtttttata tctaactttt catccaataa caaaactcct ttagcacgac
    13441 ataaattttc ataattgtcg ttaaacttgt gaatattcta aatttttaat gagcatttgt
    13501 caatggtggg attgaaacgt aaagaactag cgggtcgcag atttacacgt attgtttcgg
    13561 tgggaggagg cgcgaaaaat cttgcatggc tacaaatcca agctgatatt ttcgatgcaa
    13621 cggtctattg tttaagtgtg gaggaaggac ctgcattagg cgcaacaatg attgctgcac
    13681 tagggttagg gtggttcgac acacctgaaa gttgttgtca gaattttatc caatatacag
    13741 atgcagtgga acctctctta caaaatgtag aaaagtatca taaaatctat caacaatgcc
    13801 ggaaaatcta tccagcaacg aaggaaattt gtcatgactt ataaaacaaa acgcgtacct
    13861 aatagtcaaa tgactaatat tgggtacgcg ttaagtcttc tttacttcat cctttgcatg
    13921 attcgtgttt ttaaagcaag gtctgctgta tttcttgtgg atttaggatg gttgttatcg
    13981 tttacttgct atttttcatt gaaatcgtct ttctttaccg tttctttagt tttttatcta
    14041 tttttttctt ttggttagaa aattcttttt cccgaaagtc ttctttcagg atttttatag
    14101 agtagcgttt tgaataagag gcgtcagtat gatcgacttg gcagacgaac caagagaaca
    14161 tttgcctttt ttctgcatga ggtgcttctg ctaataattc tttccataaa taataacagt
    14221 cctctatcag aagaagggtt cgttcatcct caggctccca atagaatgtt tcgagagtag
    14281 caatcacttc attgatcaat tcgaatgcgg gaagataggc attttgctga ataagcgatt
    14341 caactgcttc ttggatgaac tttcgcatct ccatgatgaa cttcgctgtt ttcctgtttt
    14401 tgtttttctt gataatatga tcgtatttat ggatgatagt tgttaattta tctgaataat
    14461 ttattgcatg aaatggcatc ttaactttga agcgttcgat aaagtgcgga tgttctataa
    14521 gaatctctgt taaaagctcc cgtacaagag aggaactagc ggaggaaaca agggacgaga
    14581 gttcggaaag tgagtagttg gattttttta ttggacgttc ttcgtaagcg aataagacag
    14641 cagccatgtg tttgcatttt tttccttcta tggcatatag acaatcacaa gtcatgttgg
    14701 tcttttcatc ccaagtgatc actaccttat aatcttccgt gccagaaact gttgcggaca
    14761 agtacttgct tgtatagttc aaatgacgga caaaaccgtg cagatgatag ctgtaaccgc
    14821 gttccaaaac gttttcagga aaatactcaa gccaattatt catctagttc tcctttcatg
    14881 aaacacttat ttatatttag tataaagaaa cgtttaagaa aaaagtagct gattttacat
    14941 atttgataat cacttttgct cgaattgtca aaaattcatt ctccttttct tttcttagag
    15001 aatgtgagaa aaagtaaaag aatagcgtgt tttaaagatg gaactttttt tgttttttat
    15061 ttatctgaca aaaatgaagt gattttgtta gaaataaata attgttccaa ttgataaaag
    15121 aggtatgatg tatcgcaaag a
//
LOCUS       DAFBVQ010000061        14934 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.064, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000061 DAFBVQ010000000
VERSION     DAFBVQ010000061.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14934)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14934)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14934
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.064"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..153
                     /locus_tag="LLC22_002210"
     CDS             <1..153
                     /locus_tag="LLC22_002210"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBK5435466.1"
                     /translation="NKFYQSLRTASSTIKGMETIRGIYKKNRRNGTLFSFSVSTEIKV
                     LMGITA"
     gene            159..575
                     /locus_tag="LLC22_002211"
     CDS             159..575
                     /locus_tag="LLC22_002211"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435467.1"
                     /translation="MEFREGAFDFQTSQQNRKFIPEDFQNLQLENMRLEDLFRLADDD
                     KYRFEVLKIKKNELLNKLYPENAIKAHFGDANHMYSWFIPKRFRGKINAGDQVKVLNR
                     NSTDVVMITDIYVEDEVIIKYMKPVIKLVNKNKGNG"
     gene            681..944
                     /locus_tag="LLC22_002212"
     CDS             681..944
                     /locus_tag="LLC22_002212"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5435468.1"
                     /translation="MAKTVLNPSSARKNFYKLLKDVNENHTEIEIISERSENNAVLIG
                     LDDLKAIKETLLLEQIGTLGVVRKREKDDSGFTNVDEIDWDNL"
     gene            944..1216
                     /locus_tag="LLC22_002213"
     CDS             944..1216
                     /locus_tag="LLC22_002213"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBK5435469.1"
                     /translation="MNNYSVMIKNSAKADLKKIKQSNLKPQFEKVIQTLKEDPYLPTQ
                     SFEKLKPTYEGRYSRRLNRQHRVVYKVDEDEHVVEIYSARTHYESQ"
     gene            1293..1622
                     /locus_tag="LLC22_002214"
     CDS             1293..1622
                     /locus_tag="LLC22_002214"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877489.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5435470.1"
                     /translation="MITKTRKQGNSIMLTVPKDFNVPNGVEVEAKLVENGILYEFVEP
                     QKEFYDFSEDILSDIIAEGYDKDEILVEFKNRKNKMHSSFRDIAEDTLTNSKVMTKEE
                     LATEIGL"
     gene            1612..1899
                     /locus_tag="LLC22_002215"
     CDS             1612..1899
                     /locus_tag="LLC22_002215"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBK5435471.1"
                     /translation="MAYEIVPSKHVIKYLKKLKEKPLKEKFLNLIYDEIAIDPYKGEQ
                     KTGDLSGIWSSGFKYAGTTYRVAYEIIENKVIPVLLCGTHENFYEQLKKLI"
     gene            2185..3042
                     /locus_tag="LLC22_002216"
     CDS             2185..3042
                     /locus_tag="LLC22_002216"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334620.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK5435472.1"
                     /translation="MVAKKYVIGNFKGGVGKSTCAQMLGFESAVNEGKRTLIIDLDMQ
                     GNTSDVMNLTHMNFTNEEGGGEGEPIVYENTVTDVLINNLPPKEAVYKVINNLYILPA
                     DMSFEMYDDWIKDQYNDSLSQFKYMKEKLEPLFDEFDVIYLDVPPSISVYSKSAMYIA
                     DWAIVVLQTQVKSMRNAMQYLEYMDFFVKEFDTNLYVAGVIPFMLESGDAVDQEMYKQ
                     AQEIYGEHLIKNVVLKNARLKRYDGSGITMEKTKKGLLKQWDRKSHELFISILKELEE
                     HENWYAEVE"
     gene            3043..3591
                     /locus_tag="LLC22_002217"
     CDS             3043..3591
                     /locus_tag="LLC22_002217"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335394.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435473.1"
                     /translation="MADIKGLDIFGNNKGLAKIKKEAEAKKKQQAITPSENKQLEVHQ
                     VQEIKTSSNVERQSRGRTKKVGAPIRKFDKVYSTKHPLKLSTLLNATSRVLVEKYETN
                     MTRDELLRKALDEYIKQNLTQEDKQDLFNDVVKELDLFREKYPIVPELDDRGEIIRTT
                     SQIKQDTEDSLRKGWGMNNKVR"
     gene            complement(3884..4831)
                     /locus_tag="LLC22_002218"
     CDS             complement(3884..4831)
                     /locus_tag="LLC22_002218"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303155.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-binding transcriptional regulator"
                     /protein_id="HBK5435474.1"
                     /translation="MHLEFSDYESLLVKICEDYYLEDINISEISKKYGITRYKALKYI
                     EDAREKQLVSISINSPYARNYELEEIFKNYFKTNIYILKSSEDLSQHDLLFSKFAADY
                     IQELIKKANVVALSWGDTVYKVIDQFKMGAREELIFTQFIGEIGKYNSLAGSTRLVQK
                     AAERYESSYLTLSIPLYVINETARELMALEPSLANTLATASHADMLISGIGTLSSIDS
                     VEPWNKHRKILFPSMTDTVGFLYGRPFNINGEFIKASEDKTFGLSLKEIFDIPKRIGI
                     CKSKFKAESCLGALNGNFFTDLFLDEKTAWKILSLIKKE"
     gene            5019..6206
                     /locus_tag="LLC22_002219"
     CDS             5019..6206
                     /locus_tag="LLC22_002219"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent malic enzyme"
                     /protein_id="HBK5435475.1"
                     /translation="MLDEVLEIHKKNVGVLRMETTEAVQDDQDLAKMYTPGVAELSLM
                     IEKNHALARELTISGKLVAVITDGSAVLGLGNVGNQAGLPIVEGKALLYKNLAGVNAI
                     PLAIEQKSVDEIVQTIVNLQNSFAGIHLEDIAAPKCFEIEEKLQEKLSIPVYHDDQEG
                     TAIVVLAGLINAAKIQRKTLTELRVLINGMGASGVATARLLIAAGIKNLTLVDKQGRL
                     KKQDSTLNKYQRELLDHIHDTNNNASVLEDAIVGQDVFIGLSIGNVLTPEMIGKMNDN
                     PIIFALANPVPEITPDLAKESGAKLIATGSSKYPNQVNNILVFPGLFKGLLLSKANKV
                     DLSLQLEVAKQLAAKVAEPTVEKFIPNVFDEGVANVVSQAVLDYLQKLKENEDNIHAE
                     NIK"
     gene            6187..7491
                     /locus_tag="LLC22_002220"
     CDS             6187..7491
                     /locus_tag="LLC22_002220"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303157.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-hydroxycarboxylate transporter family protein"
                     /protein_id="HBK5435476.1"
                     /translation="MLKTLNRIKIGFIPLSLYIILVLAYLAMTISNIVPENDMLVSLG
                     IMTVFAYLLEEIGKTIPILKDLGGKVLVVTFLPAFLVYKHWLPQSTVTVVSDFMNNNN
                     FLMFFITLLVVGSIASMNRQTLVKATSRIIIILILCDVIGSLIGTGVGILLGLSAWNA
                     YFFIVAPIMAGGVGEGAMPLSIGYAAILSGMGQNDIFGKILPCVMLGSLVAVLLSGML
                     KKIGEKYPQLNGQGNLIDGDDEHLENLKGSAKPVNIEKTLLAGVVAITIYFVAVYVEH
                     LLKSLLGFSIPSPVILLVSLMGAKMLGFIPKNIEEGGNSLYGFTVRGITPPLLFGVGV
                     AKTDWLELIEVFKNPATIVTIIVTVVAIVATAFIAAKFLKMYPVDTAIAVSCCSGQGG
                     TGALAILAAGDRMELMPFAQVAVRLGGAMTVTFAIFLMGLLS"
     gene            7517..8530
                     /gene="citC"
                     /locus_tag="LLC22_002221"
     CDS             7517..8530
                     /gene="citC"
                     /locus_tag="LLC22_002221"
                     /EC_number="6.2.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="[citrate (pro-3S)-lyase] ligase"
                     /protein_id="HBK5435477.1"
                     /translation="MFDQTDIQRLFLKNNYIKDQWENLLLDSGIQKKQIEDFQHLDQT
                     LGIYHKEKLVGTVSYQNNVIKYIAVSEKYKDGGHTFNVLVSAIIQAMSQQEIFHYIVF
                     TKPRYQKSFNFLGFETIVSTPKIAVLEMGDSSIKQYLERIPKVNGEKKAAIVMNANPF
                     TEGHYYLVKQAANNNDWVYVFVLEKEQNLFSTKDRLKLVQQGLQKLKNVIVLSGGEYI
                     ISPATFPTYFLREDDEIAKEQMVVDATLFKERIATYLDISARYVGEEPLSPMTRSYND
                     ILETILPPEIKVHVLARKKTEQHQVISASQVRKAYLAGQLEKIKYMVPETTYQYLKNK
                     RER"
     gene            8534..8827
                     /gene="citD"
                     /locus_tag="LLC22_002222"
     CDS             8534..8827
                     /gene="citD"
                     /locus_tag="LLC22_002222"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177560.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase acyl carrier protein"
                     /protein_id="HBK5435478.1"
                     /translation="MEINKSAIAGTLESSDVQIMISPNTEGIEIDLDSQVIEQFGKQI
                     KKVIYDTLAVYQIKNVKLKVVDKGALDCVIVARLKTAIHRSLGIQHQETPWEV"
     gene            8832..9737
                     /gene="citE"
                     /locus_tag="LLC22_002223"
     CDS             8832..9737
                     /gene="citE"
                     /locus_tag="LLC22_002223"
                     /EC_number="4.1.3.34"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate (pro-3S)-lyase subunit beta"
                     /protein_id="HBK5435479.1"
                     /translation="MMKERLRRTMMFVPGNNPAMIKDAGIYGADSIMFDLEDAVSMAE
                     KDSARMLVAEALKTVDYGDTELIVRINDLHSEFGRADIFAMVKAGAHVLRLPKTETSE
                     DITEVEKVIIEAENYHNVPIGRTLMMAAIEGASGVLNAPAIAKASDRLIGIAIGAEDY
                     VTNMKTKRYPDGNELFFARSMIVHAARAAGISAFDTVYSDVDDMEGFLNEVRLIHQLG
                     FDGKSCINPRQIPVVNTVYQPSIKEIKRSLDIISAIEEAKEKGSGVISLNGKMIDKPI
                     VERAQRTLMLAKASRLIDEEGNIHA"
     gene            9730..11289
                     /gene="citF"
                     /locus_tag="LLC22_002224"
     CDS             9730..11289
                     /gene="citF"
                     /locus_tag="LLC22_002224"
                     /EC_number="2.8.3.10"
                     /EC_number="4.1.3.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase subunit alpha"
                     /protein_id="HBK5435480.1"
                     /translation="MHNKQRRSIPSSVLTKYKKEFQSVSLSPQTIQRCAPKVTTVTNQ
                     TNKLMHSIKEAIEKSGLKDGMTISFHHHLREGDFVFNQVMAVIREMGIKELTLAPSSL
                     TNTMNEMVIECIKDGTVTHITSSGMRGSLGEFISHGGMDNPVILRSHGNRPRAIESGE
                     LKIDVAFLGVPTSDDYGNANATVGKSVFGSLGYAKVDAQYADKVILLTDHLVPYPNTP
                     ISIPQTQVDYVVEVEAIGDPNKIGAGATRFTKNPKELKIAEMVKDVIVHSPYFKDGFS
                     FQTGTGGAALAVTRYLASEMEEKQIKASFALGGITKPTVDLLEKGLVEKVLDVQDFDK
                     GAAEGMARLENQQEIDASFYADPSNKGAVVNQLDVAILSALEIDTNFNVNVMTGSDGV
                     LRGAIGGHQDAATAKLTIISAPLVRGRIPTVVNDVTTLITPGKSIDVLVTEVGVAINP
                     QRKDLIAIFERIPQIPVFTIEELQQKAEKIVGIPEPLQFTDRIVAYVEYRDGSILDVV
                     RQVKEFEEERS"
     gene            11286..11843
                     /gene="citX"
                     /locus_tag="LLC22_002225"
     CDS             11286..11843
                     /gene="citX"
                     /locus_tag="LLC22_002225"
                     /EC_number="2.7.7.61"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate lyase holo-[acyl-carrier protein]
                     synthase"
                     /protein_id="HBK5435481.1"
                     /translation="MMFDTGEIQEIEDILIHKEQRANLQSNLLSKYSNSSLMVFTLNI
                     PGPIKNNPMIEQVFRQGQQSIQQMFLKKKVEMTYTKEINLPSGLDWYVIVTEAPLNLK
                     KWLVTLEEQDALGRLFDLDVLFKKGEQITIVSRQALNHGERPCFICGKSAKVCARNRT
                     HTVKEMQKKIEQIVADSLKGALKHA"
     gene            11836..12699
                     /gene="citG"
                     /locus_tag="LLC22_002226"
     CDS             11836..12699
                     /gene="citG"
                     /locus_tag="LLC22_002226"
                     /EC_number="2.4.2.52"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330401.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="triphosphoribosyl-dephospho-CoA synthase CitG"
                     /protein_id="HBK5435482.1"
                     /translation="MHDNIQKIAQEAQLAMLYEVTCINKPGLVDPVDPGSHQDMDIFT
                     FLQSSVVLTPYFEEFIQTGLDRQHQPIEETFMAIRQIGLEAETAMFSVTNGINTHKGA
                     IFSLGIFLAICGRLTIWKVPCKKSFFQKEIQKMTKNLLNDFGKIDQTKPKAWTWGEYL
                     FVNHGLTGIRGEAKRGYPCVFDRGLPYYQAYQGSQQDKMIDTLLFLSMEVEDTNLIKR
                     SNNRHVFEEYQLLIRPYFELGGVKTIQGKKYLDYLNQQFKKKNWSIGGSADLLILTIF
                     LDKIMDKGWLC"
     gene            12933..13342
                     /gene="tnpA"
                     /locus_tag="LLC22_002227"
                     /pseudo
     CDS             12933..13342
                     /gene="tnpA"
                     /locus_tag="LLC22_002227"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
     gene            complement(13979..>14934)
                     /locus_tag="LLC22_002228"
     CDS             complement(13979..>14934)
                     /locus_tag="LLC22_002228"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBK5435483.1"
                     /translation="GTLELKVPRTRDGHFSPTVFERYQRNEKALIASMLEMYVSGVST
                     RKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPYLMTDVLYIKVRE
                     ENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWITFFEYLKERGLQGTELVISD
                     AHKGLVSAIRKSFTNASWQRCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAR
                     EAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRR
                     REKIIRIFPNCVSANRLIGAVLIDQHDEWLSSSRKYIKFAK"
BASE COUNT         5267 a         2253 c         2938 g         4476 t
ORIGIN      
        1 aataaatttt atcaaagtct ccgtacagcc tcttccacga ttaagggcat ggagaccatt
       61 cgaggaatat ataaaaagaa ccgaagaaat ggaacgctct tcagcttttc ggtgtctact
      121 gaaatcaagg tattaatggg aataacagcc taagatattt ggagttcaga gagggcgcgt
      181 ttgattttca aacttcgcaa cagaaccgaa aatttatacc ggaagatttt caaaacttac
      241 agttagaaaa catgcgttta gaagatttat ttagattagc agatgatgat aagtatagat
      301 ttgaagtttt gaaaattaaa aagaatgaac tattgaataa gttatatcct gagaatgcga
      361 taaaagcaca ttttggtgat gctaatcata tgtatagttg gttcattcct aaaagattta
      421 gagggaaaat caatgctgga gatcaagtga aagtactcaa tcgaaatagt acagatgtcg
      481 taatgataac agatatctac gtagaagatg aagttataat caaatatatg aagcctgtga
      541 taaaacttgt taataaaaat aaaggaaacg gataacactt tacaatgctg ttttggtact
      601 ccaatttaaa caaaacaatc gaatttacgt acttaattaa gtacgttaga atggagatat
      661 aaattagagg gggagtagat atggcaaaaa cagtcttaaa tcctagctca gcacggaaaa
      721 atttttataa gttgttgaaa gatgtaaatg agaatcatac ggaaattgaa atcattagtg
      781 agcgcagtga aaataatgcg gtgcttattg gtttggatga tttgaaagca atcaaagaaa
      841 cgctattact tgagcaaata ggcactttgg gtgttgttcg taagcgagaa aaagatgata
      901 gtggatttac taatgttgat gaaattgatt gggataactt ataatgaata actattctgt
      961 gatgattaaa aactcggcta aagctgattt aaagaaaatc aaacagtcta atttgaaacc
     1021 tcaatttgag aaggttattc agactttaaa ggaagatccc tatctcccta cccaatcatt
     1081 tgagaagtta aaacctacat atgaaggtag gtattctaga agattgaata gacaacaccg
     1141 ggttgtttat aaggtagatg aagatgaaca cgtggttgaa atttattcag caaggacgca
     1201 ttacgagtca cagtaattac ttgtaaatac attatctcgt ggtataatgt atttactaag
     1261 taattacata ctgttagaaa tgagggattt aaatgattac aaaaacaaga aaacaaggca
     1321 attcaatcat gttgacagta cctaaagatt ttaatgttcc taatggagtc gaagttgaag
     1381 caaagttggt agagaatggt attctttatg aatttgttga accacaaaaa gaattttatg
     1441 attttagcga agatattttg tctgatataa ttgcagaagg ctacgataaa gatgagattc
     1501 ttgtagaatt taagaataga aaaaacaaaa tgcattcttc ctttagagat attgctgaag
     1561 atacacttac taattctaaa gtaatgacta aagaggagtt ggcaacagaa attggcttat
     1621 gaaatcgttc cttcaaaaca tgtcattaag tatttaaaaa agctaaaaga gaagccattg
     1681 aaagaaaaat ttttgaattt aatttatgat gaaattgcga ttgatccata taagggtgaa
     1741 caaaaaactg gggatttatc aggtatttgg tctagtgggt tcaaatatgc gggcacaaca
     1801 tatagagtag cttacgagat tatagaaaac aaggttattc cagtattgtt atgtggaacg
     1861 catgaaaact tttatgaaca gttgaaaaaa ttaatctagt gatttgttgt cgttcttaag
     1921 aaggacggct tcttttttat cgaaaatctg attcgtctac atgactaaag tcgcgagtat
     1981 tctctgcttc tcgataaatt aaataacgtc attactttga ggaaagctat aaatcaatat
     2041 atttcaactt ttccttattt atgtactacc ttttacttat taattataag gtagtacata
     2101 tatatctttt ttttggtagt aactaaaaat aaatatgtta taatagtatc aaatgaatat
     2161 tgctaaaaga aaagaggtag gaacgtggta gcgaagaaat atgtaattgg taattttaaa
     2221 ggtggcgtag gtaaaagtac gtgcgcgcaa atgttagggt ttgaatcagc agttaatgaa
     2281 ggaaaaagaa ccttgataat tgacttggat atgcaaggaa atacttctga tgtgatgaac
     2341 ttaacgcata tgaacttcac taacgaagaa ggaggcggag aaggtgaacc gattgtttac
     2401 gaaaatactg tgactgacgt gttgataaac aatcttccac ctaaagaggc tgtctataaa
     2461 gtaatcaata acctctatat acttccagca gatatgtcct ttgaaatgta tgatgattgg
     2521 atcaaagacc aatataatga ttcattatcc caattcaaat atatgaaaga aaagctagaa
     2581 ccattatttg atgagtttga cgtcatctat ttagatgtcc caccttctat ttctgtatat
     2641 agtaaatccg cgatgtacat tgcggactgg gcaatcgtcg tcttacagac ccaagtaaaa
     2701 tcgatgagaa atgcgatgca atatcttgag tatatggact tttttgtgaa agaatttgat
     2761 acaaatttat atgttgctgg tgttattcct ttcatgttgg aaagcggtga cgcagtagat
     2821 caggaaatgt ataaacaagc ccaagagatt tatggggaac atttgattaa aaatgttgta
     2881 ctcaaaaatg cgcgcttaaa acgatacgac ggatcaggta ttacgatgga gaagacaaag
     2941 aaaggtctct taaaacaatg ggatcgcaaa agccacgaat tatttatcag tattttgaaa
     3001 gaattggaag aacacgagaa ttggtatgcg gaggtggagt aattggctga catcaaagga
     3061 cttgatattt ttgggaacaa caaaggactc gccaaaataa aaaaagaagc agaagcaaag
     3121 aaaaagcagc aagcaattac accatctgaa aataagcaat tagaagtgca ccaagttcaa
     3181 gaaataaaaa cttcctccaa tgttgaaaga cagagtagag gaagaacaaa aaaagttggc
     3241 gcaccaatca gaaagtttga taaggtttat tccaccaagc atcctttaaa actgtcgact
     3301 ttgttaaatg cgacttccag agttttagta gaaaagtatg agactaatat gacaagagat
     3361 gaattgctta gaaaagcttt agatgagtat attaaacaga atcttacgca agaagataag
     3421 caagatttgt ttaatgacgt ggtgaaagaa ctagacttgt tcagagaaaa atatccaatt
     3481 gttccagaat tagatgaccg tggagaaata ataagaacta ccagtcagat aaaacaagat
     3541 accgaagact cactgcgcaa agggtgggga atgaataata aagttagata gaaccccctt
     3601 tttatagcat aaaaaagatt tagaaggata tatgatctgc atgagaagta caataaaatt
     3661 aataagaagt aacattaacg aaaaaacgtg gaaattattc agtgaataca aagaaattaa
     3721 atcttgaaaa gtaatggagt atggcttgga aaagttcaaa aaatatcaag acaagcttct
     3781 caaaaaaagg gattttgata tccaataaaa agagtgaatc attgtactgc cctccaaaaa
     3841 agtagtacca aaaatctaaa ttttttggag gattttacat gactcactct ttttttatca
     3901 aagaaagtat tttccaagca gttttttcat ccaaaaataa atctgtaaaa aaattaccat
     3961 tcaaggcgcc taaacaactc tccgctttga acttactttt acaaatacca attcgttttg
     4021 gaatatcgaa aatttctttt aaagaaagac caaaagtctt atcctcagat gctttgatga
     4081 attcaccatt gatattgaag ggtcttccgt aaagaaatcc aacagtatcc gtcatgcttg
     4141 gaaataggat tttacgatgc ttgttccagg gttcgacaga atcaatagag gataaggtgc
     4201 caattccaga aattaacata tctgcatgcg aagcggttgc taaggtatta gctaaagaag
     4261 gttctagagc cattagttca cgtgcagttt cattgatgac atataaagga atactgagag
     4321 tcaaataaga agactcataa cgttcagcag ctttttgaac taatcgtgtg gagccagcta
     4381 aggaattata ttttccgatt tcgccaatga attgagtaaa aattaattct tcacgagcac
     4441 ccattttaaa ctgatcaatc actttgtaaa cggtatctcc ccaagatagt gcaaccacat
     4501 tggctttctt aattaattct tgaatgtaat cggcagcaaa ttttgaaaat aataaatcgt
     4561 gttgtgataa gtcttcacta ctttttaata tatagatatt cgttttaaag taatttttga
     4621 agatttcttc tagctcataa ttcctagcat acggagaatt aattgaaata ctaactaatt
     4681 gtttttcacg tgcatcttca atatatttta aagctttata tctggtgatc ccatattttt
     4741 tagaaatttc actaatattg atatcctcga gataatagtc ttcacaaatt tttacaagga
     4801 gtgattcata gtcagagaat tccagatgca tagtatagct cctaactttt tcaaatagat
     4861 attttttctc attataccaa aaaaattgaa tttagtcttt ttttaaattt ttaaaaataa
     4921 gcatcatttt tttaaaattt aaaatgaaag ggttttttta ttttaaaaaa agtgttaaag
     4981 tggttttgta attaaaaaat gtaaaaagga gtgaaggtat gcttgatgaa gttttagaaa
     5041 tccataaaaa aaatgtaggt gttttacgga tggaaacaac agaagccgtg caagatgatc
     5101 aagatttagc aaaaatgtac accccaggtg tagcagaact aagtttaatg attgagaaaa
     5161 atcatgcttt ggcaagagaa ttaacaatta gtggtaaatt agtggccgtt attacagacg
     5221 ggtcggcggt attaggtctt ggaaatgtag gaaaccaagc tggattacca atcgtcgaag
     5281 ggaaagcgct gctttataaa aatttagcag gtgtcaatgc gattccatta gccatcgaac
     5341 aaaaatcagt agacgagatt gtacaaacaa ttgtcaattt gcaaaatagt tttgcaggga
     5401 tccatttaga agatattgca gcaccgaagt gttttgagat tgaagaaaaa ttacaagaaa
     5461 aactttctat tcctgtgtat catgacgatc aagaaggaac agcgatagtt gttttagctg
     5521 gattgatcaa tgctgctaag atccaaagga aaacattaac tgaacttcga gttttgatca
     5581 acggcatggg agcatctggg gttgcaacag ctagactatt aatcgctgct ggtatcaaaa
     5641 atctaacatt ggtggataaa caagggagat taaagaagca agatagtaca ttaaataaat
     5701 atcaaagaga gttgttggat catatacatg atacaaataa taatgcaagc gttttggaag
     5761 atgcaatcgt tggacaagat gtttttatcg gtctttcaat aggaaatgtt ttaacgcctg
     5821 aaatgattgg aaaaatgaat gataatccga ttatttttgc tttagccaat ccagtaccag
     5881 agatcacacc cgatttagca aaagaatctg gtgcaaagct aatcgctaca ggttcttcga
     5941 aatatcctaa ccaagtaaac aatattttag tatttcccgg attgttcaag ggactattac
     6001 tatcgaaagc gaataaagtc gatctttcat tacaacttga agtagccaaa caattagctg
     6061 ctaaggtcgc agagcctacg gtagaaaaat tcatccctaa tgtttttgat gaaggagtcg
     6121 caaacgtcgt ttcacaggca gttttggatt atttacaaaa actaaaagaa aacgaggata
     6181 atatacatgc tgaaaacatt aaatagaatt aaaattggtt ttattccttt atctctttat
     6241 atcattttgg tactcgcgta tcttgcaatg acgataagca atatcgttcc agaaaatgat
     6301 atgttagttt ctttgggtat tatgactgtt tttgcttatt tattagaaga aattggtaaa
     6361 actattccta ttttaaaaga tttaggtggt aaagtattag ttgttacatt tttgcctgca
     6421 tttctagtct ataaacattg gctacctcaa agtactgtaa ctgtggtttc tgattttatg
     6481 aataataaca atttcttgat gttctttatc acactactag ttgtcggcag tattgcttca
     6541 atgaatcggc aaacattggt taaagcaact tcacgtatta tcattatttt aattttatgc
     6601 gatgtgattg gttctttgat aggaacaggt gtgggaatac tccttgggct atctgcttgg
     6661 aatgcgtatt tctttatcgt tgcgccgatt atggctggtg gtgttgggga aggagcgatg
     6721 ccattatcga ttggttatgc agcaatatta tctggtatgg gacaaaatga tatctttggg
     6781 aagattctac cgtgtgtgat gttgggaagt ttagtcgcag ttctactgtc tggtatgctc
     6841 aaaaaaattg gagagaaata cccacaatta aatggtcagg gtaatttgat cgatggggat
     6901 gatgaacatt tagagaactt gaagggttca gctaaaccag tcaatattga aaaaacattg
     6961 ttagcaggcg tggtagcaat aacgatttat tttgttgctg tctatgttga gcacttatta
     7021 aaatcactcc ttggcttttc tattccttca cctgtgatct tattagtctc tcttatgggg
     7081 gctaaaatgc ttggttttat ccctaaaaat atcgaagaag gtggaaattc gttgtatgga
     7141 ttcactgttc gtgggatcac acctccctta ctttttggcg taggggttgc aaaaacagat
     7201 tggttagagc tgatcgaagt atttaaaaat cctgcaacga tagtaacaat cattgtgacg
     7261 gtagtagcta ttgtcgctac agcttttatc gccgcaaaat ttttaaaaat gtacccagtt
     7321 gatactgcca tcgcagtttc atgttgtagc ggacaaggcg gtacaggtgc tttagctatc
     7381 ttagctgcgg gtgatcgcat ggaattaatg ccatttgcac aagttgctgt tcgactaggg
     7441 ggtgctatga ccgtaacgtt cgctatcttt ttaatgggtc tgctatcata agaacataaa
     7501 gaaaggacgt gaccatgtgt ttgatcaaac agatatccaa cgattatttt taaaaaataa
     7561 ctatatcaaa gaccaatggg aaaatctttt gcttgattca ggaatacaaa agaagcaaat
     7621 cgaagatttt caacatttag atcaaacatt gggtatatac cataaagaaa agttagtagg
     7681 aacagtatct tatcaaaaca acgtgattaa atatatcgcc gtgtctgaaa aatataaaga
     7741 tggtggacat acatttaatg tactagtctc tgcaataatt caggcaatga gtcaacaaga
     7801 gatttttcat tatattgttt tcacgaaacc gcgctatcaa aaaagtttta actttttagg
     7861 ttttgaaaca atcgtatcta ccccaaaaat agctgtatta gaaatgggag atagttctat
     7921 aaaacagtac ctagagagga ttcctaaagt gaatggtgaa aaaaaagcag caattgtcat
     7981 gaatgcgaac ccatttacag aagggcatta ttatttagta aaacaagctg ccaataacaa
     8041 cgattgggta tatgtatttg tactcgaaaa agaacaaaat cttttttcga cgaaggaccg
     8101 actcaaatta gttcaacaag gattacaaaa actgaaaaat gtcattgttc tatcaggtgg
     8161 cgagtatatt attagccctg caacgtttcc cacctatttt ttacgagaag atgatgaaat
     8221 agcaaaggag caaatggtcg tagatgctac tttattcaaa gaaagaattg ccacttattt
     8281 agatatctct gctagatatg tgggagaaga accactttcc ccaatgactc gttcatataa
     8341 cgacatactg gaaacgattt taccccctga aataaaagtt catgtccttg caaggaagaa
     8401 aacggaacaa caccaagtta tttctgcttc tcaagttcgt aaagcgtatc ttgctgggca
     8461 attggaaaaa ataaaatata tggttccaga aacaacctat caatacttaa aaaataaaag
     8521 ggagcgttaa gtaatggaaa taaataaatc agcgattgct ggaacattag agtcaagtga
     8581 tgtccaaatc atgatttcac cgaatacaga aggaatagaa atcgatttag acagtcaagt
     8641 gattgagcaa tttggaaaac aaatcaaaaa agttatctat gacacactag cagtttatca
     8701 gattaaaaac gtaaaactca aggtagtaga taaaggggca ttagattgcg ttattgttgc
     8761 acgattaaaa acagcgatcc atcgttcctt aggtatccaa caccaagaaa caccgtggga
     8821 ggtttaatta gatgatgaaa gaacgtttga gaagaacaat gatgtttgtt ccaggaaata
     8881 atccagcgat gatcaaagat gcaggtattt atggtgctga ctcgattatg ttcgacctgg
     8941 aagatgcagt gtctatggca gaaaaagaca gcgcaagaat gcttgtggct gaggcattga
     9001 aaacagtgga ttatggtgac acagaattaa ttgttcgaat aaatgacctg cactcagaat
     9061 ttggacgtgc agacattttt gcaatggtta aagccggcgc gcatgtatta cgtttaccta
     9121 aaacagaaac ctctgaagat ataacagaag tagaaaaagt gattatagaa gcagaaaact
     9181 atcataatgt tccgataggg cgaacattga tgatggcagc cattgaaggt gcttctggtg
     9241 tattgaacgc acctgcgatc gccaaagcat ctgatcgatt gattggaatc gccattgggg
     9301 cagaagacta tgtgacaaat atgaaaacca aacgatatcc agatggaaac gaattgtttt
     9361 ttgctcgcag tatgatcgtt catgctgcac gtgcagcagg catttccgca tttgacactg
     9421 tttactctga tgtggatgat atggaaggat ttttaaacga agtacgttta atccatcaat
     9481 taggttttga tggaaaatct tgtatcaatc cacggcaaat tccagtagtc aatactgttt
     9541 atcagccgtc aatcaaagaa atcaaacgat cactagacat catctcggca atcgaagaag
     9601 caaaagaaaa aggttctggc gtaatttctt taaatggaaa aatgatcgat aaaccaattg
     9661 tagaacgtgc acaacggaca ttgatgttag caaaagcatc acgattgatt gatgaggagg
     9721 gaaatatcca tgcataataa acaaagacgt agcattccat caagtgtttt aacaaagtat
     9781 aaaaaagaat tccaaagtgt ttcattatcg ccacaaacga ttcaacgttg tgcaccaaaa
     9841 gtaacgactg taactaatca gacaaataaa ttgatgcact cgatcaaaga agctatagaa
     9901 aaatcgggct taaaagatgg aatgacgatt tcatttcatc atcatttgag agaaggtgat
     9961 tttgttttta accaagtgat ggccgtgatc cgtgaaatgg gcatcaaaga attgacctta
    10021 gcaccaagtt ctttaacgaa cactatgaat gagatggtta ttgaatgcat caaggacggt
    10081 acagtaactc atatcacaag cagtgggatg cgcggcagct taggtgaatt tatttctcat
    10141 ggaggaatgg acaatcctgt gattttacgt tctcatggta atcgtccacg tgcaattgaa
    10201 agtggtgaat tgaaaatcga tgttgcattt ctaggagtac caacatctga tgattatgga
    10261 aatgctaatg cgactgttgg aaaatccgtt tttggttcat tagggtatgc aaaagtagat
    10321 gcacaatatg cagataaagt cattcttcta actgatcatt tagttcctta ccctaatacg
    10381 cccattagta ttccgcaaac acaagtcgac tatgtcgtgg aagtagaagc aattggtgat
    10441 ccgaataaaa tcggtgctgg tgctacacgg tttactaaaa acccaaaaga attaaaaatt
    10501 gctgaaatgg tcaaagatgt cattgttcac tcaccttatt tcaaagatgg cttttctttt
    10561 caaacaggaa cgggtggtgc agctttagca gtaacgcgtt acttagctag tgaaatggaa
    10621 gaaaaacaga tcaaagcttc ttttgcatta ggtggcatca ctaaaccaac ggttgattta
    10681 ttggaaaaag gtcttgttga aaaagtgtta gatgtccaag actttgacaa aggagcagct
    10741 gaaggaatgg cgcggcttga gaaccaacag gagatcgatg cttcctttta tgctgatcca
    10801 agtaataaag gagcggttgt taaccaatta gatgtcgcta ttttatctgc attagaaatt
    10861 gacacaaact tcaatgtaaa tgttatgact ggttcagatg gtgtgctaag aggtgcgatt
    10921 ggtggacatc aagatgcagc aacggctaaa cttactatca tctcagcgcc gttagtacgt
    10981 ggccgaatac ctacagtagt aaatgatgtt actacattga tcacaccagg gaaaagtatc
    11041 gatgtattag tcacagaagt aggggttgct atcaatcccc aacgtaaaga tctaatagct
    11101 atttttgaaa gaattccaca aattcctgtt tttacaatag aagaattaca gcaaaaagca
    11161 gaaaaaatag taggcatccc ggaacctttg caattcacag atcggatagt tgcctatgta
    11221 gaataccgag atggttcaat tttagatgtc gttcgtcagg tgaaagaatt tgaagaagag
    11281 agatcatgat gtttgatact ggagaaattc aagaaatcga ggatattttg atccataaag
    11341 aacaacgtgc taacttgcaa agcaacctgc tttccaagta ttcaaatagt tcattgatgg
    11401 tctttacatt gaatattcct gggccgatca aaaataatcc aatgattgag caggtatttc
    11461 gtcagggaca gcagtcaatt cagcaaatgt ttttaaaaaa aaaggtggaa atgacgtaca
    11521 caaaagaaat caatttgcca agtggattgg actggtacgt aatagtaaca gaagcacctt
    11581 tgaatctcaa aaaatggttg gtcacgttag aagagcaaga cgcattaggt agactttttg
    11641 atttagatgt cttgttcaaa aaaggagagc agataacaat tgtcagtcgc caagctctta
    11701 atcatgggga acgtccttgt tttatttgtg ggaaatcagc aaaggtatgt gcacgtaatc
    11761 gtacacatac tgtgaaagaa atgcaaaaga aaatcgaaca aatagtagcc gattccttaa
    11821 aaggagcatt gaaacatgca tgataatatt caaaaaatag cacaagaagc acaattagcg
    11881 atgctttatg aagttacatg tatcaataaa ccaggattgg ttgatccagt agaccccggg
    11941 tctcatcaag atatggacat ttttactttt ctacaaagta gtgtagtttt gactccctat
    12001 tttgaagaat ttatccaaac aggattggac cgacaacatc aaccaattga agaaaccttt
    12061 atggcgattc gacagattgg tttagaggct gaaactgcga tgttctcagt gacaaatggt
    12121 ataaatacac ataaaggtgc tatcttttca ttggggattt ttcttgctat ttgtggccgg
    12181 ttaactattt ggaaagttcc ttgtaaaaaa agtttctttc aaaaagaaat tcaaaaaatg
    12241 acgaaaaatc tacttaacga ttttgggaag attgatcaaa caaaaccaaa agcatggact
    12301 tggggagaat atctatttgt taaccatgga ttgacaggga tacgagggga agccaaaaga
    12361 ggttatcctt gtgtttttga ccgaggattg ccttattatc aagcatatca agggtcgcaa
    12421 caagataaga tgatagacac tttacttttt ctatcaatgg aagtagaaga taccaatttg
    12481 atcaaacgaa gtaataatag acatgttttt gaagagtatc aattacttat tcgtccttat
    12541 tttgaattag ggggtgtaaa aaccatacaa ggtaaaaaat atttggatta cctaaatcag
    12601 caatttaaaa agaaaaattg gagtattggt ggaagtgcag acttattgat ccttacaatc
    12661 tttttagata aaatcatgga caaaggatgg ttatgttgat actataatac attattttgt
    12721 attagtaagc taataactaa aaaatggttc aatacaaata ttttataaaa aatggtagtg
    12781 cctatccttt cagattgtag acaaagaaaa atttctttgt ctacaatttt tttgttaatg
    12841 acttcagtca gtttcgtgcg caaagcgtgc gaaacaagaa aaccatgcgt ttctacacgt
    12901 ggaagaacta gcatatcgaa aggagttttt tcatgtcaaa tgacgataaa agtttagccc
    12961 atactcgttg gaattttaag tatcatattg tatttacacc aaaatatcga cgaaaagtaa
    13021 tctataggca attacgaaaa gatattggaa aaatacttag gaagttgtgc aaaataaaaa
    13081 acgtggaaat tatagaagca catgcaacgc cagatcatat tcacatgctt gttcaagtac
    13141 catcaaaaat aagtatatcc agttttatag ttatctgaaa gatcgtagtg ctgtgctaat
    13201 ccacgagcag cacgtaaatc acaaatatag atacggaaat aaatcatttt ggtcggagga
    13261 atattatgtg agtacagtcg aattgaatca aaagacaatt gaaaaataca tccgtgaaca
    13321 agaagctgat gatcgcattt gagatagtat aagtaaaaga gagtagatgt tgcaataaca
    13381 aaagggtaaa aatggactac ctccagtaaa ataccgaaaa atagtttaac ttttggagat
    13441 aagtccattt aagggtctat agaatgacaa tttttttagg ggattttact attattactt
    13501 caagacccgc ttggattcgc aaagtgagtg aactcttaaa actacctgat agtaggttgt
    13561 tttaagagtt atctgaaagt aaaaattgca tttatatttt tgataaatac gtaaatttat
    13621 atatacgtat ttatcaaagt tttaggccaa aggaatattg tgtaaataca ctaggattga
    13681 atgaatagac cagaagaaat tgcgtccaag aacaaaagaa gcatgatagt gctctatata
    13741 aattgggcat tcaagaatct gaaatttaaa ggtagaattt tagttagact tttagatttt
    13801 aaacacaaaa ataaccatac aagcaacaag aagcaaagtg ctatattata aattgtccgt
    13861 ccgtttactt acataagatc attggggcta tttttaaaag agaataatag ataataaatg
    13921 aaaaaaaagt caagtccaca atcctgtgta aaatactata caatgctctc actatttttt
    13981 acttggcaaa tttaatatat tttcttgatg aagaaagcca ctcatcgtgt tgatcaataa
    14041 ggactgctcc aattaaacga ttggctgaaa cgcagtttgg aaagatacga ataatttttt
    14101 ctcttctgcg cacttcttga ttcagtcgtt caattagatt ggtactcttt agtcgattgt
    14161 gggaatttcc ttgtacggta tattgaaagg cgtcttcgaa tccatcatcc aatgatgcgc
    14221 aagcttttga atattttggt tgatcgatat aatcatgaat caatcgattt ttagcctcac
    14281 gagctaagtt aatatctgtg aacttaaaaa ttcctttaac agcttctctg aaagattttg
    14341 aatttttttt aggaatggtg gtaaagatat ttcttaggaa gtgaacttgg catctttgcc
    14401 aacttgcgtt ggtgaaggat tttctaatgg cagagactaa tcctttgtgc gcatcagaaa
    14461 taacgagttc tgtaccttgt aaaccgcgtt cttttaggta ttcaaaaaat gttatccagg
    14521 tctcttcgct ttcgccactt tgaatcatga agccgataat ttcacggtcg ccatctttgg
    14581 ttattccaat cgctatatga cagctttttg agagtactcg attttcttct cgtactttta
    14641 tatagagtac atcggtcatt aagtaaggat aatttttttc tgataataaa cgattctgcc
    14701 actcgttaac cattggttct agctgttctg ttaagctaga aacgaaggac ttagagacgg
    14761 atttaccaca aagttcttcc acaatttttg atactttacg agttgaaacg cctgatacat
    14821 acatttccaa cattgaagca atgagggctt tttcgtttcg ttgataacgt tcaaacactg
    14881 tgggtgaaaa atggccatca cgtgttctgg gtacttttaa ttctagcgtg ccta
//
LOCUS       DAFBVQ010000062        14900 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.065, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000062 DAFBVQ010000000
VERSION     DAFBVQ010000062.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14900)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14900)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14900
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.065"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     misc_feature    111..236
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00558"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L20 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00558"
     gene            280..804
                     /gene="infC"
                     /locus_tag="LLC22_002229"
     CDS             280..804
                     /gene="infC"
                     /locus_tag="LLC22_002229"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010750600.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-3"
                     /protein_id="HBK5435484.1"
                     /translation="MTIAKDMMVNDGIRARELRLIGSDGEQLGVKTKAEALNIAEQAN
                     LDLVLVAPGAKPPVARIMDYGKYRFEQQKKDREARKKQKVINVKEVRLSPTIDLNDFN
                     TKLRNARKFLEKGDKVKASIRFKGRAITHKEIGQKVLNRLAEETADIATVEQKAKMDG
                     RSMFLTLAPKNDSK"
     gene            876..1076
                     /gene="rpmI"
                     /locus_tag="LLC22_002230"
     CDS             876..1076
                     /gene="rpmI"
                     /locus_tag="LLC22_002230"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001125942.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L35"
                     /protein_id="HBK5435485.1"
                     /translation="MPKQKTHRGSAKRFKRTGKGGLKRFRAFTSHRFHGKTKKQRRQL
                     RKASMVSSGDFKRIRQQLAKMK"
     gene            1129..1488
                     /gene="rplT"
                     /locus_tag="LLC22_002231"
     CDS             1129..1488
                     /gene="rplT"
                     /locus_tag="LLC22_002231"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723984.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L20"
                     /protein_id="HBK5435486.1"
                     /translation="MARVKGGTVTRKRRKRVLKLAKGYYGSKHTLFKTAKEQVMNSYN
                     YAYRDRRQKKRDFRKLWIARINAAARMNGLSYSKLMHGLKVAEIDINRKMLADLAVND
                     AAAFTALADQAKEALAK"
     gene            1740..3047
                     /locus_tag="LLC22_002232"
     CDS             1740..3047
                     /locus_tag="LLC22_002232"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="citrate transporter"
                     /protein_id="HBK5435487.1"
                     /translation="MSDIIIGILLVISFFFMVWYCVKGYNLMVGFAIMATVWMGLALV
                     GNTFSPNPAMEGQGVIDVLTHIYTTGPAEYAKSILVNVFFGAFFGRVLVDSGIAATLI
                     RKVVELGGDKPRITMSLLCIVTAVIFMSMTGIGPVISIAVIVLPILMSLGISVPVALF
                     SFMGSIMAGIFANIVNFKQYQTIYAGFNPAAESYTYNDYFQIGMIGMIVSLVVVLTVA
                     NISMNKKKRYAMAANVPAEGGDAPMISWLAVLLPVLGVVLLDLPIILGFILAGIWALL
                     FTGKLRGGYKEICRQFAKLFTDGAVDVAPMVGFLMTLAMFNNSAAYASPYFSAIFGDW
                     IPQSPLVLAIVFAILTPLGFFRGPMNLVGSGSAILAVVLAVNPTMSPAFLFPLFAITT
                     IAPQHLDITQSWVAWGLGYTKVTSREYMKKSIPTGWIIGAIFA"
     gene            3124..5253
                     /locus_tag="LLC22_002233"
     CDS             3124..5253
                     /locus_tag="LLC22_002233"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydantoinase/oxoprolinase family protein"
                     /protein_id="HBK5435488.1"
                     /translation="MKRFVRMGIDVGGTHTKAVAIDNATHEIIGKSSVKTTHDDVRGV
                     AAGVVQSFQNCLRENNISPEDVVFVAHSTTQATNALIEGDVAKVGVIGMAKGGLEGFL
                     AKQQTRLNDIDLGNKKKIEIVNAFLPVKHLNVDRVSETISSLERERAEVLVSSMAFGV
                     DNGEPERVVYEAASVKSIPTTMASDITKLYGLTRRTRTAAINASILPKMLDTATSTED
                     SVREAGVNVSLMIMRGDGGVMEINEMKKRPVLTMLSGPAASVMGSLMYLRASNGVYFE
                     VGGTTTNIGVIKNGRPAIDYSIVGGHPTYISSLDVRVLGVAGGSMVRANQSGIIDVGP
                     RSAHIAGLDYAVFTETEKIKGPKVEFFSPKEGDPADYVKVVMEDGEEVTITNTCAANV
                     LGLVQEEHFSYGNVPSARKAIQALADYCHTTVEDIAEQIMEKSYAKIEPVILELADKY
                     HLEKDQISLVGVGGGAASLITYFSNKMGVKYSIPENAEVISSIGVALAMVRDVVERII
                     PSPSKEDIRSLKNEAMNKAIESGATPESIEVHVEIDPQTSKVTAIATGSTEVKATDLT
                     KEITTEEALELAAEDMRLNKNEVCLLENTPFFYVCGEQNRSKNAGSLRIIDQKGFIKV
                     QRGHASCMKTTAANYMTAVEQLWEDMAVYQTELIARPEFYLCLGARVSDFTATDLEQL
                     QLLMDLEVSTMEPEEEVIVVAGNIKQT"
     gene            5228..5917
                     /locus_tag="LLC22_002234"
     CDS             5228..5917
                     /locus_tag="LLC22_002234"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002307432.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435489.1"
                     /translation="MPEISNKHKLEELLNELQQIPEEIWGFYQFRRDLFWKKIPLSKQ
                     KILIQQSIDCGIETACSIKKKYPFADVGEICEQMAVPIVSCESEQINERITFATYAED
                     EGIRLMTEPLEKLKCSGLASISKETAQALIIGHELFHHIEASVKGIYTQSEKIVLWRL
                     PFYTHQSNIRALSEIAAMSFSKEMNQSDFSPYVLEAVLLWPYNEIRSQGILEEIKKIE
                     KRCTEYDLDYK"
     gene            complement(6325..7011)
                     /locus_tag="LLC22_002235"
     CDS             complement(6325..7011)
                     /locus_tag="LLC22_002235"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374310.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5435490.1"
                     /translation="MVINNLQQQAYESIRKQIIYSELAPGSKISDKVLEEQLAIGRTP
                     IREALIQLRNQELVKTIPQSGTYVSKIDIRSASLARYTREKLEKPILQECSAKMTKQD
                     QAKLEKILEQTDQAVIAQNKKAFFDLDTDFHRTCYEIAGKREIWDWLESYSTHLNRFR
                     WLRLTISELDWGRVLDEHQTMLQSMIDHNFDEVGFLCTMHLHMIIEEQEYVIHNYPDY
                     FEDIQDRPIK"
     gene            complement(7147..7341)
                     /locus_tag="LLC22_002236"
     CDS             complement(7147..7341)
                     /locus_tag="LLC22_002236"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435491.1"
                     /translation="MKRKKQVIPMYVVKVMHGYIDKTGCRTREKNLDNLLIFKDKKES
                     EAFAKRIGGRVKPIQEVRPD"
     gene            complement(7391..7831)
                     /locus_tag="LLC22_002237"
     CDS             complement(7391..7831)
                     /locus_tag="LLC22_002237"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331188.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acyl-CoA thioesterase"
                     /protein_id="HBK5435492.1"
                     /translation="MEKFTGYVREPFYYETDQMGIIHHSNYIRWFEEARVALLVHLGF
                     PYKKIEESGIIIPVLEVNCSYKEMIHYGEKVSIHPTIQKYTGTRLDFSYEIVGTEDKK
                     LKTTGSSKHCFLLSDSQRLVKLSKVNPELDQLFQAYASLDDVNS"
     gene            complement(7835..8680)
                     /locus_tag="LLC22_002238"
     CDS             complement(7835..8680)
                     /locus_tag="LLC22_002238"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008264125.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-hydrate dehydratase"
                     /protein_id="HBK5435493.1"
                     /translation="MLINEQLVKRIITPRPKISHKGTFGRIVLIGGNEQYGGAIIMSA
                     LAAVHSGAGLTTVVTDEKNRSALHSHLPEAMIVVWTDTDQFLSVIKQADVLLIGPGLG
                     TSSKSLERFKQVLENQSKEQWLVIDGSALSLLAANHLLLPYPEQTVLTPHQMEWQRLS
                     SLPIQEQRDKENKKKQQEIGAVLVLKSHETKIYGHQHFYTNPLGSAAMATGGMGDTLA
                     GMITGFLAQFPQNDQTIAAAIYLHSFIGDQLAKEQYIVLPTQISEALPKWMNYFCKKS
                     MENEA"
     gene            8829..10247
                     /gene="pepV"
                     /locus_tag="LLC22_002239"
     CDS             8829..10247
                     /gene="pepV"
                     /locus_tag="LLC22_002239"
                     /EC_number="3.4.13.-"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dipeptidase PepV"
                     /protein_id="HBK5435494.1"
                     /translation="MTIDWQKEVEARKEDLLEDLKNLLRVNSERDDSKVTPDAPFGPG
                     PRDALKHMLAYGERDGFKVKNVDNYAGHIDLGEGDETLGIFGHMDVVPAGDGWDTDPY
                     EPVIKDGKIFARGSSDDKGPSMAAYYAMKIIKELDLKLSKKVRFVVGSDEESGWGDMA
                     YYFEHEEEPDFGFSPDAEFPIINGEKGNVSLALRFKGDNAGDYVLKSFVSGLRENMVP
                     GTATAALQVPSADAAIAMEEAFYQFIEANPVSGTIEADNTYVKIELVGKGAHGASPQS
                     GINAGSFLALFLDNYEFLGSAKQFIHVAAAYVHEDFYGEKLGVAYEDEKMGKLTMNAG
                     LFAFEENGTEEANFINMNFRFPKGVTVDGLQSDIEQTVGQEGATVTRGARVMEPHYVP
                     MDDPLVATLLQVYEDHTGEKGYEQIIGGGTYGRLLKRGVAYGAMFPGYTDTMHQANEF
                     MSLDDLFRATAIYADAIYRLAK"
     gene            complement(10304..11251)
                     /locus_tag="LLC22_002240"
     CDS             complement(10304..11251)
                     /locus_tag="LLC22_002240"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase"
                     /protein_id="HBK5435495.1"
                     /translation="MEQQEKIAVLIPCYNEEATISTVIADFKRELPEADIYVYDNNST
                     DRTYELAVQGGAIVKKEPRQGKGNVIRQMFFDIDADYYLMVDGDDTYPAEAVHGLLEK
                     LRSGEADMVIGDRLSNGTYFDENKRPFHDFGNNLVRNTITRMYKTKILDVMTGYRGFN
                     RIFVKSFPIMSSGFQIETELTIHALDKKFKFVEIPIDYRDRPEGSESKLNTFSDGFKV
                     IMMIIKMFKDYKPLLFFGIWTIFFFLFGLVTGIPVIREYMLTSFITRIPSAILSTGLM
                     TLALLSLVTGLILDTVVTNAKKEYELNLYHVYHEYHSRK"
     gene            complement(11474..11824)
                     /locus_tag="LLC22_002241"
     CDS             complement(11474..11824)
                     /locus_tag="LLC22_002241"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339502.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PepSY domain-containing protein"
                     /protein_id="HBK5435496.1"
                     /translation="MYEESELSYFKGGLAVGIGLGLLSGVASTIWYHRKKVLSADQVL
                     ENIKSSFLKEGAIEGSWISFEKEPIRKFAVRSSAYRGGLSRIEDGETVYYEFLADAHT
                     GTVLEISRKKGATD"
     gene            12024..13103
                     /gene="pepA"
                     /locus_tag="LLC22_002242"
     CDS             12024..13103
                     /gene="pepA"
                     /locus_tag="LLC22_002242"
                     /EC_number="3.4.11.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutamyl aminopeptidase"
                     /protein_id="HBK5435497.1"
                     /translation="MEEKTFQRIKELTELQGTSGFEQDVRAYMESHMEPLVDELQLDG
                     LGGIFGLRHHEEADAPRVMVAAHMDEVGFMLTQIQENGLFKVVPLGGWNPYVVSAQRF
                     TLKTSTGKNYPCISSSVPPHLLRGTSGQKSVEVTDILFDAGFESREEAMSYGVLPGDT
                     IVPYAETIKTANGKNIISKSWDNRYGCTMVLEALEALQNETLGHTLIAGANVQEEVGL
                     RGSKASVNKFKPDLFFAVDCSAADDTVTKNGTFGHLGEGTLMRIQDPGLIMLPRLREY
                     LLDIAETNNIPYQYFVSKGGTDAGAAHTQNEGIPSTVIGVVGRYIHTHQTMFSIRDFE
                     AAREMLIQTLKGLDKSTVNTIVYGK"
     gene            13247..13567
                     /locus_tag="LLC22_002243"
     CDS             13247..13567
                     /locus_tag="LLC22_002243"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374322.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="thioredoxin family protein"
                     /protein_id="HBK5435498.1"
                     /translation="MIIPNSLEELAGYVETGKSVFFFTAGWCGDCRFIKPQMPEIEND
                     FSDWQFIEVDRDKYIDVAAEWNIFGIPSFVVIQDGKELGRLVNKDRKTKQEIESFLES
                     VTKG"
     gene            13589..14053
                     /locus_tag="LLC22_002244"
     CDS             13589..14053
                     /locus_tag="LLC22_002244"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287838.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5435499.1"
                     /translation="MNQEYKNILVGIDGSEQALAAFKKAVEVARRNNGKVYVANVIDQ
                     QFYNFMGYAPIDQNLVDQQTETAKEMIEECKEYGKSVDYTNIEGIIAYGSVRESMAVK
                     LPKKYEIDLIMVGQSGLNAVERFMTGSVASYVIRHSPCDVLIVSDEEEQPSN"
     gene            14258..14863
                     /locus_tag="LLC22_002245"
     CDS             14258..14863
                     /locus_tag="LLC22_002245"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294153.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4479 domain-containing protein"
                     /protein_id="HBK5435500.1"
                     /translation="MIFAYNKAHVGDTLMVIIADDKGTENTVERKWNVARIKDEQGQV
                     VAWNFFHISDHLTIEGNGQVSLTDEELAKLNRLIKEAGFEEQLEADHEPKIVVGYVKT
                     CVPHPDSDHLSITETEVDNGTVLQIVCGAPNIEAGQKVVVAKPGAMMPDGMMIWPGTL
                     RGVDSYGMICSARELHLPNAPAKKGILVLPEDAVVGEAFPK"
BASE COUNT         4739 a         2749 c         3115 g         4297 t
ORIGIN      
        1 ggaatcactg ctagaaagtc tgctaatcta atcattttca gaaaaggaag acaaactgta
       61 tgaaaaacat tgacaaaaag attagttttt gctatactat gatggttgag aaataaaagc
      121 agaagcaccc gcttctcgcc ttagttgata atgtcactgg gctagatagt tttcactggt
      181 tctattaggt gaagtacgcg cgggttctgt aagagaactc gtttttttat tgccgtttat
      241 tcggtaagct tttctttctc tcataatatt tggaggtgaa tgaccatagc aaaggatatg
      301 atggttaacg acggcattcg tgcacgagag ttacgattga tcggttcaga tggtgagcaa
      361 ttaggagtta agacaaaagc agaagcattg aatattgcag aacaagcaaa cttggatctt
      421 gtgttagttg cccctggtgc gaaaccacca gttgcgcgaa tcatggacta cggtaaatac
      481 cgtttcgaac aacaaaagaa agaccgcgaa gcgcgtaaaa aacaaaaagt gatcaatgta
      541 aaagaagttc gcttaagtcc tacgatcgac ttgaatgact tcaatacaaa acttcgtaat
      601 gcacgtaagt tcttggaaaa gggcgataaa gtgaaagctt ctatccgttt caaaggccgt
      661 gccattaccc ataaagaaat tggtcaaaaa gtcttgaatc gcttagctga agaaactgcg
      721 gatattgcaa cagtggaaca aaaagcgaaa atggacggac gcagcatgtt cttgacgctg
      781 gcaccgaaaa acgacagtaa gtaatttgaa tgactaactg gctgttggac agccgatagt
      841 cggataacga aagattttga ggaggaaata tagtcatgcc aaaacaaaaa acacaccgcg
      901 gatcagcaaa acgtttcaaa cgtactggta aaggcggatt gaaacgcttc cgcgcgttta
      961 caagtcaccg tttccacggc aaaacaaaaa aacaacgccg tcaattgcgt aaagcaagca
     1021 tggtttctag tggcgacttc aaacgtattc gccaacaact agcaaaaatg aaataagaag
     1081 tacaaataac agaatctgaa gatttatttt tattaggagg aattatacat ggcacgtgtt
     1141 aaaggtggaa cagtaactcg taaacgtcgt aaaagagtgc taaaattagc aaaaggttac
     1201 tacggttcaa aacacacttt atttaaaaca gcaaaagaac aagtaatgaa ttcatacaac
     1261 tacgcatatc gcgatcgtcg tcaaaagaaa cgcgacttcc gtaaattgtg gattgctcgt
     1321 atcaacgcag cagctcgtat gaatggcttg agctactcaa aattaatgca cggtttgaaa
     1381 gttgctgaaa tcgacatcaa ccgtaaaatg ttagctgact tggctgttaa cgatgcagca
     1441 gcatttactg cattggctga ccaagcaaaa gaagctttgg ctaaataagc taaacaatta
     1501 taaagaggaa agaagataac gaaaagttat gttctttcct ctttttttat ttacaatcct
     1561 ccatcaaatg aaacaggaca ataacgtata agtctaaaat agcataatta aggtttttta
     1621 attgaaaact gaacatttat ggtcaccctt taatgaaagc gctaactaca taagttagaa
     1681 tgagtttgac tgatatatta gtttgcttat cagaaaaaca aaatggacgg aggaataaca
     1741 tgagtgatat tattattggt attttgttag ttatctcatt ctttttcatg gtctggtact
     1801 gtgtaaaagg ctacaacttg atggtcggct ttgccatcat ggctactgta tggatgggat
     1861 tagcgctagt cggaaacacg ttttcaccaa acccggcgat ggaagggcaa ggagtaattg
     1921 atgtgttgac gcatatctat acgacggggc cagctgagta cgccaaatcg atcttggtaa
     1981 atgtcttctt tggtgccttt ttcgggcgtg ttctagtaga tagcggaatc gcagctaccc
     2041 tgattcgaaa ggtagttgaa cttggagggg acaagccaag aatcacgatg agcttactat
     2101 gtattgtaac cgctgttata ttcatgtcga tgacaggaat cggaccagtg atttctattg
     2161 cagttattgt gttgccaatc ttgatgtcat taggtatttc agtaccggtt gcactgttct
     2221 catttatggg ctcgattatg gctggaatct ttgctaatat cgtcaatttc aaacaatatc
     2281 aaacgattta tgctggtttc aatccagcgg ctgaaagcta tacttataat gactatttcc
     2341 aaattggtat gattgggatg attgtaagct tagttgtggt actaacggtc gctaatatat
     2401 caatgaacaa aaagaaacgc tatgcaatgg cagcaaacgt accagctgaa ggtggcgacg
     2461 caccaatgat ctcatggtta gccgtattat taccagtttt aggggtcgtt cttttagatc
     2521 ttccaatcat cttaggtttt attctagcag gtatctgggc attgctgttt actggaaaat
     2581 tgcgcggagg ttataaagaa atctgtcgtc agtttgcgaa attatttaca gatggcgcag
     2641 tagatgttgc accaatggtt ggtttcttga tgaccttagc gatgttcaat aattcagctg
     2701 cgtatgcttc tccttatttt tcagctattt ttggagattg gataccgcaa tcaccattag
     2761 tcttggcaat cgtatttgct atattgacac cactaggatt tttccgcggt ccaatgaatc
     2821 tagtcggttc aggctcagct attttagctg tcgtattagc tgttaatcca acgatgtcgc
     2881 cagccttttt gttcccgtta tttgcaatca caacgattgc tcctcagcat ttagatatta
     2941 cacaatcttg ggttgcttgg ggattaggtt atacaaaagt aacttctcga gaatatatga
     3001 agaaatccat cccaactggt tggatcatcg gagcgatctt tgcctgatca cgttcttatt
     3061 gtacgggaac gcctagtaaa caaaacgtcg ataaaaacga ttagatgaat ggaggaaaag
     3121 aaaatgaaac gttttgtgcg aatgggaatt gatgttggcg gtacacatac gaaagcagtc
     3181 gcaatcgata atgcgacgca cgaaatcatc ggaaaatctt cagtgaaaac aacccacgat
     3241 gatgtccgtg gagtagccgc aggtgtcgtt cagtcttttc aaaattgttt gcgggaaaat
     3301 aatatcagtc cagaagatgt tgtgtttgtt gcacattcta ccacacaagc gactaatgca
     3361 ctgattgaag gagacgtagc aaaagtcggc gtaatcggga tggcaaaagg tggattagaa
     3421 ggttttttag caaaacaaca aactagattg aacgatatcg atttagggaa taagaaaaaa
     3481 atagagattg tcaatgcatt cttacctgtc aaacacttaa atgtagaccg tgtttcagaa
     3541 acgatttctt ctttagaaag agaaagagcg gaggtcttgg tttcttctat ggcatttgga
     3601 gtagataatg gggaaccaga acgagttgtt tatgaagcag catcggtaaa atcgatccct
     3661 acaacgatgg cttctgacat cacaaaatta tatggattga caagaagaac tcggacagca
     3721 gcaatcaatg catctatttt accaaaaatg ctagatacgg caacctctac agaagattcc
     3781 gtacgagaag caggggtcaa tgtttctttg atgattatgc gcggagacgg cggagtaatg
     3841 gaaatcaatg aaatgaaaaa acgacctgtt ttaaccatgc tttccggtcc agcagcatca
     3901 gtcatgggct ctttgatgta cttgagagcg tctaatggtg tttattttga agtaggcgga
     3961 acaacaacca atatcggggt cattaaaaat ggacgtccag caatcgatta ttcaattgta
     4021 ggtggccacc caacatatat ctcttcatta gatgttcggg ttctaggtgt ggcaggcggt
     4081 tcgatggtac gggctaatca gtcaggaatc atcgatgtcg gtccacgttc tgcacatatt
     4141 gccggtctag attatgcagt atttacggag acagaaaaaa tcaaaggtcc taaggttgaa
     4201 tttttctctc ctaaagaagg agaccctgct gattacgtca aggtagtgat ggaagacgga
     4261 gaagaagtga ctattacaaa tacatgtgca gccaatgtcc ttggattagt gcaagaagaa
     4321 catttttctt atggaaatgt cccatctgca cgaaaagcca tccaagcatt agctgattat
     4381 tgtcatacga cggttgaaga catcgcagaa cagatcatgg aaaaatccta tgctaagatt
     4441 gaaccggtga ttttagaatt ggcagacaag tatcacttgg agaaagatca gatttctctt
     4501 gtaggtgtag ggggcggcgc tgcctcattg attacttact ttagtaataa aatgggtgtg
     4561 aaatattcga ttcctgaaaa cgccgaagtg atttcttcta ttggtgtagc acttgcaatg
     4621 gtccgagatg ttgtagaacg tatcatccct tcgccaagta aagaagatat acgatcgttg
     4681 aaaaatgaag cgatgaataa agcgattgaa tcaggcgcta caccagaatc gatcgaagtc
     4741 cacgtagaaa tcgatccaca gacttcaaaa gtaacggcta tcgctactgg ttctacggaa
     4801 gtgaaagcaa ccgatctaac caaggagatc acaacagaag aagcactaga gcttgctgca
     4861 gaggatatgc gattaaataa aaatgaagtt tgcttattgg aaaatacacc tttcttttat
     4921 gtatgcggcg aacagaatcg ttcaaaaaat gctggaagtc ttcggatcat cgatcaaaaa
     4981 ggatttatca aggtccaacg tggacatgct tcatgtatga aaacaactgc agccaattat
     5041 atgacagctg tcgaacaact ttgggaagat atggcagttt atcaaactga attgattgcc
     5101 cgaccagaat tttatctctg cttaggagca agagtctctg attttacagc gacggatctg
     5161 gaacaactac agcttttgat ggatctggaa gtatctacta tggaaccgga ggaagaagtg
     5221 atcgtcgttg ccggaaatat caaacaaaca taagttagaa gagttactaa acgaattaca
     5281 acagatcccc gaagaaattt ggggattcta ccagtttcgg cgagatttat tttggaaaaa
     5341 gattcctttg tccaagcaga aaattcttat acaacaatca atcgattgtg gtatcgaaac
     5401 ggcatgtagc atcaaaaaaa agtacccttt tgccgatgta ggagaaattt gtgaacaaat
     5461 ggctgttcca atcgtttcct gtgaatcaga gcaaataaac gaacgaatca cttttgcaac
     5521 ttatgcagaa gatgaaggga ttcgattgat gacggagccg ttagaaaaat taaaatgttc
     5581 aggactagct tcgatctcta aagaaacagc gcaagctttg attattggac atgaactatt
     5641 tcaccacatc gaagcttctg ttaagggaat ttatacgcaa agcgaaaaaa ttgtgctgtg
     5701 gcggttgcct ttttatacac atcaatcaaa cattcgtgca ttgagcgaga tagcagcgat
     5761 gagtttttca aaagagatga atcaaagcga tttttcgcct tatgtattag aggcagtctt
     5821 actttggcca tataatgaaa ttcgtagcca agggatctta gaagaaataa aaaaaataga
     5881 aaaaagatgt acggagtatg atttagatta caaataaaga gactgtgaca aaagtcgtgt
     5941 cacagtcctt tttttccgaa taaacgatgt tctcctgtca actcctcggt cacaagtcaa
     6001 aatattcaac aaacatgaga agctgttttt tgaaattgtt ccttgtgact cggagatgaa
     6061 cggcaggctc acgacctctt ggaaaacggt gttcaaaagc ttgcatctgc ggtaataagt
     6121 ccagccaagt taaaaacata agaagctatt tttacttggc tgttcttatt acttgatgca
     6181 gggcagcttt ttcacaacct ctcaataaac ggtgtgcaat cagctgaccc tcggtattag
     6241 ctcaaaaaaa acggcaaaat atgaggaact attttgccgt ttctttctct aatactcagg
     6301 tcaaaacgct gattccaaaa cctcttattt gatgggtctg tcctgaatat cttcaaaata
     6361 atcggggtaa ttatgaatca cgtattcttg ctcctcgata atcatatgta aatgcatcgt
     6421 gcaaagaaat ccgacttcat caaagttatg atcaatcatt gattgaagca ttgtctgatg
     6481 ttcatctaat actcgacccc agtctaattc tgaaatcgtc aaacgtaacc atctgaaacg
     6541 gttcaagtgc gtactataac tttctagcca atcccaaatt tctcgttttc cagcaatttc
     6601 ataacaagtt cggtgaaaat cagtatccaa atcaaaaaaa gcttttttat tttgagcgat
     6661 tactgcctga tcggtttgtt ctagtatttt ttctagttta gcttgatctt gcttggtcat
     6721 tttcgcactg cattcttgca ggatcggttt ttccaacttt tcccgcgtat aacgggctaa
     6781 tgaagcagat cggatatcga tttttgaaac ataagtgccg gactgtggaa tggtttttac
     6841 aagctcttga ttgcgcagtt ggatcagtgc ttctcgaatc ggtgtacgcc cgatagctag
     6901 ttgttcttct aacactttat cggagatttt acttccaggt gctaactcgg aataaatgat
     6961 ttgtttacgt atagattcat aagcttgctg ttgcaaatta ttgataacca tttaaccttc
     7021 ctttctatgc agatataatc tattataaca taaatcgctt acaaatcgtg tgggcataaa
     7081 aacacagtct gcaaaaaaag ccctgatagg catgcctatt agagcctcga aaagaaaaat
     7141 attgaatcaa tctggtcgta cctcttgtat cggtttgaca cgaccgccga ttcttttagc
     7201 aaaagcttcg gattcttttt tgtctttgaa aatgagcaga ttgtctaagt ttttttcccg
     7261 agtgcgacag ccagttttat cgatgtaacc gtgcattact ttaacgacat acatggggat
     7321 cacctgcttt tttcttttca ttatacgaac tactcgacac aatacaagaa aaatgcttag
     7381 acggtcttta ttaagaattt acatcatcca aagaagcgta cgcttggaat aactgatcta
     7441 actccggatt gactttgctc agcttcacta atcgttgcga atcagaaagt aaaaaacagt
     7501 gtttactact gccagtagtt tttaattttt tgtcttcagt tcccacaatt tcgtagctaa
     7561 aatccaaccg tgtccccgta tacttttgga tagttggatg gatgctcact ttttctccgt
     7621 aatggatcat ttctttatag ctgcaattta cttccagaac ggggatgatg atcccagatt
     7681 cttcgatttt tttataggga aaccctagat gtaccaataa ggctacccga gcctcttcaa
     7741 accagcggat ataattgctg tgatgaataa tccccatttg atctgtttca taataaaaag
     7801 gttctcgcac ataacctgta aatttctcca tgactcatgc ctcgttttcc attgattttt
     7861 tacaaaaata attcatccat ttcggaagtg cttcgctgat ttgtgtcggc aaaacaatat
     7921 attgttcttt tgccagctgg tctccaatga aactatgaag ataaatagct gctgcaatcg
     7981 tttggtcatt ttgaggaaac tgggctaaaa atcctgtgat catcccagct aaagtgtcac
     8041 ccatgccgcc cgttgccata gcagcagaac ctaaaggatt ggtgtagaag tgctggtgac
     8101 cataaatttt tgtctcatga cttttcaaaa cgagcacagc accgatttcc tgttgcttct
     8161 ttttgttttc tttatcccgt tgttcttgta tcggtagaga actcaaccgt tgccactcca
     8221 tttgatgagg tgtaagtaca gtttgttcgg gatagggtag caaaagatga ttagcagcaa
     8281 gtaaacttaa agcagagcca tcaatcacca gccattgttc ttttgattgg ttttctagta
     8341 cttgtttgaa acgttccaaa ctcttagaag aagtacccaa tccgggacca atcaagagta
     8401 catctgcttg ctttattacg gaaagaaact ggtcagtatc cgtccaaact acaatcattg
     8461 cttctggcag atgactgtga agagcactcc gatttttttc atcagttact acagtcgtga
     8521 gacccgctcc gctgtgtacg gcagctaaag cactcataat gattgctccg ccatattgtt
     8581 cattgccgcc aatcaaaacg atacgtccaa atgttccttt atgtgaaatt tttggacgag
     8641 gtgtgatgat tcttttcact agttgttcgt ttatcagcat ctaaaaacct ccttttactc
     8701 attatagcgt atattttttt tagagaaaaa cagataagaa aaggaattgt cagatttttt
     8761 gaactatttt tttctgtaat ttgtggtatc atgaacacga agacttaaat aagtggagga
     8821 ttaactttat gacaattgat tggcaaaaag aagtagaagc acgtaaagaa gacttgcttg
     8881 aagacttgaa aaatctttta cgtgtcaaca gcgagcgcga tgactcaaaa gtaacaccag
     8941 atgcaccatt tggacctgga cctcgcgacg cattgaaaca tatgttagct tatggcgaac
     9001 gtgatggatt taaagtaaaa aatgtcgata actatgcagg gcatattgat cttggcgaag
     9061 gagacgaaac gctagggata tttggacaca tggatgtcgt tcctgcagga gatggctggg
     9121 acacagatcc ttatgaacca gtaatcaagg atggaaagat ctttgcacgc ggatcaagcg
     9181 atgacaaagg tccaagtatg gcagcttact atgcgatgaa gatcattaaa gaacttgact
     9241 tgaaactatc aaaaaaagtt cgcttcgtag tcggcagcga tgaagaaagc ggctggggcg
     9301 atatggctta ttatttcgaa catgaagaag aaccagattt tggtttctca ccagatgctg
     9361 aattcccaat catcaatggt gaaaaaggaa atgtttcttt agctttacgc ttcaaaggcg
     9421 acaatgcagg agattatgtc ttgaaatctt ttgtttccgg acttcgcgaa aatatggtgc
     9481 caggaacagc aactgcagca cttcaagtac caagtgcaga tgcagctatc gcgatggaag
     9541 aagcatttta ccaattcatc gaagcaaatc cagtaagcgg aacgattgaa gcggacaata
     9601 cgtatgtaaa aatcgaatta gttggtaaag gcgcacatgg tgcaagccca caatctggta
     9661 tcaatgcagg ttctttcttg gcattgttct tagataacta tgaattccta ggatctgcta
     9721 aacaatttat ccatgtagca gctgcttatg tccatgaaga tttttatgga gaaaaactag
     9781 gagtcgctta tgaagatgaa aaaatgggca aattgacaat gaatgctgga ctatttgctt
     9841 ttgaagaaaa tggtacagag gaagcgaact tcatcaatat gaatttccgt tttccaaaag
     9901 gtgtaacagt agacggattg caaagtgaca tcgaacaaac agtggggcaa gaaggcgcaa
     9961 cagttactcg aggtgctcgc gtaatggaac cacattacgt accaatggat gatccattgg
    10021 tggctacatt attgcaagtc tatgaagacc acactggaga aaaaggctac gaacaaatca
    10081 tcggtggcgg aacttacgga cgtttgttga aacgtggcgt tgcttatgga gcgatgttcc
    10141 caggatatac tgatacaatg catcaagcaa acgaatttat gagtcttgat gacttgttca
    10201 gagcaacagc aatctatgca gatgccatct atcgtttggc gaaataatta attaaaaaga
    10261 ggatcaagaa ttgcaaatta tttttgcagt cttgatcctt tttttacttt ctactgtggt
    10321 attcatgata aacatgatat agattcaatt catattcttt cttagcgttc gtgacgactg
    10381 tatccaaaat caaccctgtt actaatgaaa gaagtgctaa agtcatcaat ccagtactta
    10441 aaatcgcaga agggatgcgt gtaataaagc ttgtcagcat atattcgcga atcacaggaa
    10501 tccccgtgac caatccaaat aaaaagaaga agatggtcca aatcccaaag aaaagcaaag
    10561 gcttataatc tttaaacatt ttaataatca tcatgatcac tttgaatccg tcagagaatg
    10621 tattcaattt tgattcgctg ccttcaggac gatcacgata atcgattggg atttcaacga
    10681 acttgaattt tttatctaaa gcatggatcg tcaattccgt ttcgatttga aaaccagaac
    10741 tcataatagg aaaacttttg acaaagatac gattgaatcc tcgatagccg gtcatgacat
    10801 caagaatttt tgttttatac attctagtaa ttgtatttct aacaaggtta tttccaaaat
    10861 cgtggaaagg tctcttattc tcatcaaagt aggttccatt tgataggcga tcaccaatga
    10921 ccatatctgc ttcaccagaa cgtaatttct cgagcaaacc atgtacagct tctgcaggat
    10981 aagtatcatc gccatctacc attaaataat agtcggcatc gatatcaaag aacatttggc
    11041 ggatcacatt tccttttcct tgacgaggtt ctttttttac gattgctcca ccttgaacgg
    11101 ccaattcgta tgttcgatcg gtcgaattat tatcatagac ataaatatct gcttctggta
    11161 attctcgttt aaagtctgca atgactgttg aaattgttgc ttcctcattg taacaaggaa
    11221 tcagaacagc aattttttct tgttgttcca tttttcactc tccttaacta tagaaaacaa
    11281 aagctaaatt aaaaatacct cataatcaaa ggaaatgcta gtttttcccg ctaaatatca
    11341 tttatttaaa aagaaaatac tggaatatat gtttggaaag ctctatctaa aaaaccaccc
    11401 actacaaaag aaggacatga tacctctctt ttgaatagtg ggtgcgtatt cgttctctca
    11461 cttttttgac gtattaatct gttgcacctt tttttcttga aatttctaat acggttcctg
    11521 tatgagcatc tgctaaaaat tcataataaa cagtttcgcc atcttctatt cgagaaagac
    11581 ctccccgata agcactcgac cgaacggcga atttcctaat aggttccttt tcaaaagaga
    11641 tccaagaacc ttcgattgca ccttctttta gaaaagatga cttgatattt tcaagtactt
    11701 ggtctgctga caatactttt ttgcgatgat accaaatcgt tgaagctacc ccgctcaata
    11761 atcctagacc gattccaact gctaacccgc ctttaaaata gcttagttcg ctttcttcat
    11821 acatgtggac atacctcctt cttctcactt gttactcctt gtgcttattt taccacactc
    11881 tcatattttc tttgaaataa ataaccgcta ccagaaaaaa taagctataa taaatacgat
    11941 cggtctgcag aaaaaatcat attttatccg cagatcaata taagtctgag aggagtttag
    12001 tctgaaattt agacgaatag catatggaag aaaaaacatt tcaacgaatc aaagagttaa
    12061 cagaattaca aggaacaagc ggttttgaac aagatgttcg cgcttatatg gaaagtcata
    12121 tggaaccgct ggtagatgag ttacagttag atggtttggg cggcattttt ggtctgcgcc
    12181 atcatgaaga agcggatgca ccccgtgtaa tggtcgcagc acatatggat gaagtcggat
    12241 tcatgctgac acaaatccaa gaaaacgggc tttttaaagt cgtacctcta ggcggctgga
    12301 atccttacgt tgtttctgct cagcgtttta cacttaaaac ctctactggt aagaattatc
    12361 catgtatttc ttcttccgtt cccccacatt tattgcgagg aacaagcgga caaaaatcag
    12421 tagaagtaac cgatattttg ttcgatgctg ggtttgaatc aagagaagag gcaatgagtt
    12481 acggtgtcct tccaggagac acaatcgttc cttacgctga aacgatcaaa acagccaacg
    12541 gaaagaatat tatcagtaaa tcatgggaca accgctatgg ctgtacaatg gtattagaag
    12601 ctttagaagc gttgcaaaat gaaacattag gtcatacatt gattgcaggc gcgaatgtcc
    12661 aggaagaagt aggcttgcgt ggttctaaag cttctgtcaa taaattcaag ccagatctgt
    12721 tctttgcagt agactgctct gcagcagatg atacagtgac gaaaaatggc acattcggac
    12781 atttaggaga aggtacattg atgcgtatcc aagatccagg tttgatcatg cttcctcgtt
    12841 tgcgcgagta cttgctggat atcgctgaaa caaacaatat cccttatcaa tactttgttt
    12901 caaaaggcgg tacagatgca ggtgctgctc atacacaaaa cgaaggaatc ccaagtacag
    12961 tgattggcgt agtgggacgt tatatccata cgcatcaaac gatgttcagt attcgcgatt
    13021 ttgaagctgc acgagaaatg ttgattcaaa cactgaaagg tttggataaa tcaacagtga
    13081 atacgatcgt atacggaaaa taatgcgata gtgaaactat aaaatctggc aaaagattgc
    13141 tttttgccag atttttttta taaaaagagg atcaatgttt gttagttcga aagaaaggtg
    13201 tataatttaa ttgaaaaata cataaacaga aagtagagga caaagaatga ttatcccaaa
    13261 tagtttagaa gaattagcag gctacgtaga aactggaaag agtgtatttt tctttactgc
    13321 cggctggtgc ggagactgcc gttttatcaa accgcaaatg cctgaaattg aaaatgactt
    13381 ttctgattgg caatttattg aagtagaccg tgacaagtac atagatgtag ccgctgaatg
    13441 gaacattttt ggtatcccaa gttttgtcgt gatccaagac ggaaaagaat taggtcgtct
    13501 agtgaataaa gatcgtaaaa caaaacagga aatcgaatcg ttcctagaaa gtgtaacaaa
    13561 aggctgacat ctgttaggag gggtcaagat gaatcaagaa tataagaata ttttagtagg
    13621 tatcgacggt agtgaacaag cacttgctgc tttcaaaaaa gcggtagaag tggctcgccg
    13681 taataatggg aaagtatatg tagcaaacgt aatcgatcag caattttata actttatggg
    13741 ctatgcacct attgatcaaa atctagtcga tcagcaaact gaaacagcca aggaaatgat
    13801 cgaagaatgt aaagaatatg ggaaatctgt tgattacaca aatatagaag gaattattgc
    13861 atatggttct gttcgtgaat ccatggcagt caaattgcca aaaaaatatg agatcgatct
    13921 aatcatggtt gggcagtcag gtctaaatgc agtcgaacgc tttatgacag gaagtgtagc
    13981 cagctacgtg atacgtcatt caccttgtga tgtcttgatc gtttctgacg aagaagaaca
    14041 gccaagtaat taagcaagtg gaacttgtac gaccttttta atcaattaac taaaacagta
    14101 aagggactgt gacaaaagtc ttgtcacagt cccttgttac gaataaatgg tgttccagaa
    14161 gaggcttctt cggaaataaa gcatgaaaaa aatttcatgc agtgaatgca attttttgtt
    14221 aagataaatc tcagcaaagg ataatggagg aaagaacatg atttttgctt ataacaaagc
    14281 acacgtcgga gacaccttga tggttattat agccgacgat aaaggaacag aaaacactgt
    14341 tgaacgcaaa tggaatgttg ctcggatcaa agatgaacaa ggtcaagttg ttgcttggaa
    14401 ctttttccat atctccgatc atctaacaat cgaagggaac ggccaagtaa gcttaacaga
    14461 tgaggaatta gcgaaattga atcgattgat caaagaagca ggattcgaag aacagcttga
    14521 agctgatcat gaaccgaaga tcgttgtcgg gtacgtaaaa acatgcgtcc cacatcctga
    14581 ttctgaccat ttatcgatta ctgagacaga agtagacaat ggtacagtat tgcaaatcgt
    14641 ttgcggtgca cccaatatcg aagctggaca aaaagttgtc gttgcaaaac caggagctat
    14701 gatgccagat ggaatgatga tctggccagg aactttgcga ggggtagata gctatggaat
    14761 gatctgttcc gctcgtgaat tgcatttgcc aaatgctcca gcaaaaaaag gaatcttagt
    14821 attgcctgag gatgccgtag tcggagaagc atttccaaaa taaagaggtt gtgacaagtc
    14881 tttgtcacaa cctctttttt
//
LOCUS       DAFBVQ010000063        14631 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.066, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000063 DAFBVQ010000000
VERSION     DAFBVQ010000063.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14631)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14631)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14631
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.066"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LLC22_002246"
     CDS             complement(<1..1416)
                     /gene="nhaC"
                     /locus_tag="LLC22_002246"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323773.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Na+/H+ antiporter NhaC"
                     /protein_id="HBK5435501.1"
                     /translation="MGKKGTPSFLEATLVLMVIVLGIAIGVVGLKVSPNITILAAIGM
                     VMLYAVIKRYPTDWLHEGIINGIKPGIIPIFIFILVGSLIAVWIQAGIIPTLMVIGFK
                     LISVQWFVPSVFVVCAIVGSAVGSAFTVMSTIGIAFFGIGTTLGLNPALVVGAIVSGA
                     VFGDKMSPLSESTNLAAAIVDADLFKHIKHMMWSTVPAFVVSFFLFMILGHTSKAASL
                     SSIREVTDVLEANFTISIWSLIPLFLMLLCAWKKVPAILTILLNIAVAVGMIFIQNPQ
                     TSLTKLAGVIESGFVSNTGNQQIDSLLSRGGIESMMPTVSLIILTLSLGGLLIEFGLI
                     STVMERVSRKMTNTPNLIFTTLMTSIGVNIFIGEQFLSVILPGNAFKETYEKAGFDPT
                     VLGRTLEDGGTVINYLVPWGIAGSFVASTFGIPTLTYLPFVFFSLLSPVFSMVSAFTG
                     WGISKKFVKPQEAVSKTAQLEQ"
     gene            complement(1819..3042)
                     /locus_tag="LLC22_002247"
     CDS             complement(1819..3042)
                     /locus_tag="LLC22_002247"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319046.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M20 family metallopeptidase"
                     /protein_id="HBK5435502.1"
                     /translation="MTTTISTNQLKDLIQYRLPEYQALALDIHEHPEVSNYEFYSSAA
                     LIKQLEKERFWVEKEVAGHRTAFDARYISNKPGPTIAFLAEFDALPGIGHACGHNLFG
                     TYSVLAASIVKQFIDETGGEIRVYGTPGEEGGENGSAKGSFVREGFFEDVDVALCVHP
                     AFRYGKTTESLANDPVDIKFYGVASHAAAAPEKGVNALEALIQVFNGINALRLQLPKD
                     VNIHGIITDGGVAANVIPDYAAGRFYLRAGNRQTLDKVYEKVENIVRGAAISTGTTFE
                     FGLFQNAVDDVIVTPSFDDLFFQHAKEAGVPDEEIETEQRTSLGSSDVGNVSQVIPTI
                     QPTVAISETYIAGHTEEFKAAAKSDKGLASIAIAAELLANTALDLLKEPKLLERIKQE
                     HQEIVARKKQEGATF"
     gene            complement(3073..3912)
                     /locus_tag="LLC22_002248"
     CDS             complement(3073..3912)
                     /locus_tag="LLC22_002248"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293787.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MetQ/NlpA family ABC transporter
                     substrate-binding protein"
                     /protein_id="HBK5435503.1"
                     /translation="MKKIIRFVVITFVAIIWLAGCSQGKADTTDKKETIVKLGIIGED
                     TDVWDNVKDRLKKENINLEYVKFTDYNQPNVALADGSIDLNSFQHQFFLDNYNKEHGT
                     DLVSIGNTVNAPLGIYSNTLKDVADIKDGAKVAIPNDVTNGGRALLLLQTAGLIKVDK
                     AKGQAPTVSDITENRKNLDISELDASQTARALSDVDISVINSGVAVDAGFNPASDAIF
                     LEPVDDHARPYVNIIVARKEDENNKTYQKIVDAYQTEDTVKVIEKTSKGSSVPAWETF
                     GRK"
     gene            complement(3929..4609)
                     /locus_tag="LLC22_002249"
     CDS             complement(3929..4609)
                     /locus_tag="LLC22_002249"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346795.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435504.1"
                     /translation="MTDFFKTYLPNVYLIPDEFVEATKQTLYMSFWTAFIGGMIGIIL
                     GVTLVVTRPNGLLANRLLFEILDKLINIIRSIPFIILLSLLALTTRFLVGTTIGAKAA
                     LVPLIFGVVPFFARQIENALLEVDPGVIEAAEAMGTSPIGIILRVYLLEGLPGIIRVS
                     ALTIINVIGLTTMAGAVGAGGLGNLAISRGYNRFQTDVTIVATLLILILVFLSQFISN
                     QLIKKITH"
     gene            complement(4611..5684)
                     /locus_tag="LLC22_002250"
     CDS             complement(4611..5684)
                     /locus_tag="LLC22_002250"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5435505.1"
                     /translation="MIELRDVSVCFKQKEKEIQAVDSVDLTIEKGDVYGIVGYSGAGK
                     STLVRVMNLLQKPTAGEVIVNQTNLSQLSPKELRKERKAIGMIFQHFNLMESRTIFDN
                     VDFSLKYSGKSKQERRQKVNELLELVGLEEKASAYPKQLSGGQKQRVAIARALANEPK
                     VLLCDEATSALDPKTTLQILALLKKLNRQLGLTIVLITHEMQVVKEICNKVAVMEDGR
                     IVEKGSSIQIFSNPEEELTKDFIRTATHLDQALETIIAHSAFADQIANKWLVELSYIG
                     NQTNEPLIAHLYSKYQVTANILYGNVELLQETPLGSLIVTLAGETKQRKKALDYLIKS
                     GVKINILQKNDLDSRIKVIEGGR"
     misc_binding    complement(5740..5978)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     misc_binding    complement(6021..6254)
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00230"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="T-box leader; Derived by automated computational
                     analysis using gene prediction method: cmsearch."
                     /bound_moiety="tRNA"
                     /db_xref="RFAM:RF00230"
     gene            complement(6331..7002)
                     /locus_tag="LLC22_002251"
     CDS             complement(6331..7002)
                     /locus_tag="LLC22_002251"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5435506.1"
                     /translation="MKGAIFDLDGLLVDTEKTYRDGWLWGFQQFDIHIPKEIVDAWGG
                     KNWKQSFDILVKAAGSPEKVQEVRAKREEYFYQQLTSGAIHLKPYAKEILADLKERHM
                     KLGIATTTVTKRATDILDHFKLADYLDTFTFGDEVSENKPSPIPYLTALERTGLEASS
                     AFAVEDSLVGATAASRAGLGVVLIPDSSFVRNYTVEEKEKLKLLAEGKDLRTVIEMLN
                     KKTEK"
     gene            complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LLC22_002252"
     CDS             complement(7089..9767)
                     /gene="mgtA"
                     /locus_tag="LLC22_002252"
                     /EC_number="7.2.2.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313416.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium-translocating P-type ATPase"
                     /protein_id="HBK5435507.1"
                     /translation="MSFGHKGEIEMEKKKDTQKIYAAFAGKTKQELFELFHASANGLT
                     EEQIERSRENYGENAISYGKKTPFIVEILKAYITPFTLVLIALGIISFITEYVLAAPG
                     DKDLFGVAIIFTMVIVSGTMTLIQSVRSNQAAEKLKSLVKVTAAVKRNGKYTEIPMEE
                     IVCGDLVRLSAGDMIPADMRLLSAKDLFISQAALTGESYPVEKHAKVCEDDQQSETSY
                     ENLVFMGSNVISGSAEGIIVSVGNETLFGHVAETLSEKPIQSSFELGIHKTSMLLIKF
                     MSLMAPAVIVINGLTKGDWLEAFLFGLSVAVGLTPEMLPMIVTTNLVKGASVMAKKGT
                     VIKNLNAIQNFGAIDVLCTDKTGTLTQDKIILEYHMDCEGNEDDRVLRHAYLNSYYQT
                     GLKNLLDVAIIDEATETLDTDKINYQKVDEIPFDFERRRMSVVVADPAGKTQMITKGA
                     IEEMLNISKFIDLGGTVTPLTKERKEAVLAKVQSLNEDGLRVIGVAQKTNPSVVGEFS
                     VKDESDMVLIGYLAFLDPPKETTKQALKALKEHGVAVKVLTGDNELVTRSVCRQVGLE
                     INELVTGEKISEMSDHELAQVAEDHEVFVKLNPQQKARLTTALRKNGHTVGFLGDGIN
                     DAPAMKVADIGISVDTAVDIAKESADVILLEKDLTILERGLLSGRETFGNIMKYIKAT
                     ASSNFGNMFSVLIASTFLPFLPMLPLQLLFLNLIYDVSCISLPWDRMDKEYLDEPKKW
                     NASSIGEFMVYFGPTSSIFDITTYLLMYFVICPAVVGGSFHTLDSSQRVIFIALFHAG
                     WFVESLWTQTLVLHALRTPKVPFIQSNATFAMFVITTLGIIVGSVLPFTSFGAELGLM
                     PLPGNYWLWLFATVIAYLALVTAVKKIYIRRFQELL"
     gene            10426..10863
                     /gene="ndk"
                     /locus_tag="LLC22_002253"
     CDS             10426..10863
                     /gene="ndk"
                     /locus_tag="LLC22_002253"
                     /EC_number="2.7.4.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleoside-diphosphate kinase"
                     /protein_id="HBK5435508.1"
                     /translation="MERTLVIIKPDGVRRHLVGSIIQRFEAKGLAIAEMKFETMTPEL
                     AKEHYQHLTERSFFDELIDYMTSGPVVYLVLVGEEVIDIVRKMVGATKAADAVPGTIR
                     GDYALPGTENIIHASDSRDAAVKEIARFFPPFDINKPSEKAAK"
     gene            complement(10885..11751)
                     /locus_tag="LLC22_002254"
     CDS             complement(10885..11751)
                     /locus_tag="LLC22_002254"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK5435509.1"
                     /translation="MYDGELIKKLRVNKKLTQSQLAEGICFKTSLVGIETNSVKKMSF
                     VTLRSFLERMNMTLAEYEWMRNQLDEPIKLKKKRRMLDRVQEDSFDPYKEISNNRRHF
                     KKTEDLYYLVLNLHMVEKTEVSETEFEFLRYECRIIEEYLMQIPDYGQFELSILADFP
                     WIFSDRFIENNYLKIKKRMRRLAQLNNHEQYLFTFLMNLTSFYIENGRLKKARSVNED
                     MKRSLAHKERSTVIYETLMADYYQRLISAALGEEKTKDYQEFFTVLEYMLGKNQRRSL
                     EKKLLAIAEPSN"
     gene            complement(11911..14004)
                     /locus_tag="LLC22_002255"
     CDS             complement(11911..14004)
                     /locus_tag="LLC22_002255"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344510.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBK5435510.1"
                     /translation="MTQLKKLCQNRLAIVLTAVFFFWLKTIIAYYADFSLGVEGTIQY
                     FILWINPIATTLLFFGLSLYIKKPKPALAILLIIDILNTLLLYLNIIFYREFTDFITV
                     KSVLGFSKVSQGLSGSSFSLMKPHDVIYWLDIAVFIGLLVWLKVKKIPIKSNPVGKPM
                     AIAVTCLSGLIFSGNLALSEANRPQLLQRTFDRSYIVKYLGIDAYTIYDGIKTGMTSS
                     VRAHASSNGIDEVLDYTKKHYAEPNPETFGIAKGKNVIVLHLESFQQFLINMKVDGQE
                     VTPFLNSIFQNQATISFDNFFHEVGQGKTSDAENMLETGTFGLPQGSLFTELGSDNVF
                     QAAPAILGQKQGYTSAVFHGNVASFWNRDHVYKNLGYDNFFDRSYFDESDETLGYGIL
                     DKDLFRESAQYLEHLQQPFYTKFLSVTNHTPYYTDDKNFDFPSLNTGNSTVDNYVRTA
                     HYLDQSLEQFFTYLKKSGIYQNSIFVIYGDHFGISNTDNKDLASALGKDPDTWDEFDN
                     AQMQRVPLMIHMPGYTKGTVNHEYGGEIDVLPTLLHLLGIDDKDYLHFGTDLLSSQHD
                     QVVAFRNGNFVTPKYTVLGGKAYNNQTGEIIDTKAAGIDEEISKDQEKVKTALSLSDK
                     LNQENLLRFYVPNGFETIDPKKYDYKNEAERNEAIEKQKGEHSTSVFSKNGNKTTTNL
                     YPVTRTDVEQQKNNQ"
BASE COUNT         4246 a         3136 c         2497 g         4752 t
ORIGIN      
        1 ttgttctaat tgcgctgtct tgcttactgc ttcttgcggt ttcacaaatt tttttgagat
       61 tccccaacct gtgaaggcac tgaccatcga aaacacagga gaaagcaaac tgaaaaatac
      121 gaatggcaag taagtgagtg taggaatacc aaatgtactt gctacgaaac ttccggcaat
      181 tccccaaggc actaagtagt tgattactgt tccaccatct tctagcgttc tacctaatac
      241 agttggatca aatcctgctt tttcataagt ttctttaaat gcattaccag gcagaataac
      301 agataggaat tgttcaccaa taaaaatatt tactccgata cttgtcatca atgttgtaaa
      361 aatcaaattt ggtgtgttcg tcatctttct tgatactcgt tccatcacgg ttgagatcaa
      421 gccaaattcg atcaacaatc cacctaatga caaagttaga ataatcaatg acacagtagg
      481 catcatactt tcgattcctc cgcggctaag cagtgaatcg atttgttggt ttccagtatt
      541 tgaaacaaac cctgattcga tgaccccagc caacttcgtt aaggaagttt gtgggttttg
      601 aataaaaatc attcctactg ctacagcgat attcaacaaa atcgttaaaa ttgccggcac
      661 ctttttccat gcacacagta acattaaaaa taaaggaatc agtgaccaga ttgaaatagt
      721 aaagtttgct tctagaacat cagtcacttc acgaatagat gaaagacttg cggctttact
      781 tgtgtgtcct aaaatcatga ataaaaagaa agaaacaaca aatgccggga cagttgacca
      841 catcatatgc ttgatgtgtt tgaacaaatc ggcatcaaca atagctgctg ctagatttgt
      901 tgattcggat aatggagaca tcttatctcc aaaaacggca cctgaaacaa tagctccaac
      961 aaccagcgct ggatttaagc ctagtgttgt cccaataccg aaaaatgcaa tcccaatcgt
     1021 tgacataaca gtaaaggcac tccctacagc gctacctacg attgcacaca caacaaatac
     1081 agaagggaca aaccactgga cactgatcaa tttgaaccca atgaccatta gagttggaat
     1141 gatccctgct tgtatccata cagcaatcaa tgaaccgact aaaataaaaa taaagattgg
     1201 gatgattcct ggtttgatgc cattgatgat tccttcgtgc agccaatctg tcgggtatct
     1261 ttttatcact gcatacaaca tgaccattcc gatcgctgct aagatcgtga tattaggtga
     1321 gacctttaat ccgacaacgc caatcgcaat gcctaaaaca ataaccatta atacaagtgt
     1381 tgcttctaaa aaacttggtg ttcctttttt tcccatgata atctctcctt ttttagttgt
     1441 tcttatgttc taaaaaagtt aagatatcgg attactccgc cgcaattcat ccgcgattcc
     1501 tcctttataa aaataaaaag acctgtttta aactaaggac gaatgactcc gcggtaccac
     1561 cttaattaaa aacagatctg tttttcactt tcaaactttt attcaaatgt atggactttc
     1621 catgtaattc gtcaattagg cttgatcggt tcacagcgac caccgacttt ctgaacaaaa
     1681 cacctaaccg ctactgcgtg aaaagttgac ttgtacgaag tttaccttcc ataagatcat
     1741 ttgtcaatga aaaagaaaat attttttcat ttttctgaaa attattttta taactttcac
     1801 acacaagttt attttttact agaaagtagc gccctcttgt ttttttcttg ctactatttc
     1861 ttgatgttct tgcttgattc tttctaatag ctttggctct ttcaacagat caagagctgt
     1921 attggcgagt agttctgctg caatcgcaat agaagcaagg cctttgtcac ttttagcagc
     1981 agctttgaat tcttctgtgt gtccggcaat atatgtctca gagattgcta ccgtaggctg
     2041 gattgttggt atgacttggc tgacatttcc tacatcagaa gaaccgagac ttgttctttg
     2101 ttccgtttct atttcttcat ctggaacacc tgcttctttt gcatgctgga agaataagtc
     2161 atcaaaagaa ggagtaacga tgacatcatc aactgcattt tggaacaatc caaactcaaa
     2221 agtcgtgccc gtacttatcg cagcacctcg tacgatattt tccacttttt catatacttt
     2281 atctaatgtt tgccgatttc ctgcacgtaa atagaaacgt ccagcagcgt aatctggaat
     2341 gacgttggca gctactcctc cgtctgtaat gatcccatgg atattgacat cttttggcaa
     2401 ttgcaagcgt agagcgttga ttccattaaa cacttggatc aatgcttcca aagcatttac
     2461 tcctttttca ggtgctgctg ctgcatggga agcgacaccg taaaatttga tgtcgactgg
     2521 atcattcgct aaagattctg tcgttttccc ataacgaaaa gctggatgga cgcataacgc
     2581 tacatcgaca tcctcaaaaa aaccttctcg aacaaagctg cctttagctg atccgttctc
     2641 gcccccttct tcccctgggg tgccatatac acggatttct ccaccagttt catcaatgaa
     2701 ttgcttcact atgctggcgg ctaatacgga gtaagtacca aacaaattat gcccgcatgc
     2761 atgaccaata cctggtaaag catcgaattc tgccaaaaag gcaattgtgg gaccgggttt
     2821 attggaaata taacgtgcat caaaggctgt tcggtgtcca gctacttctt tttctaccca
     2881 aaacctttct ttttctaatt gtttaatcaa cgctgctgag gaataaaact catagttact
     2941 tacttcagga tgttcgtgga tatctagagc aagtgcttga tattctggta aacgatattg
     3001 gattagatcc ttcaattggt ttgttgagat tgttgttgtc ataaaaaatt cctcctatgc
     3061 tagtcatttt tcttattttc tcccgaatgt ttcccatgca ggcacgcttg atccttttga
     3121 tgttttctcg attactttga ctgtgtcttc tgtttgataa gcgtctacta ttttttgata
     3181 cgttttattg ttttcatctt cttttcttgc aacgatgata ttcacataag gacgtgcatg
     3241 gtcatccact ggttctaaga agatggcatc agaagcagga ttaaatccag catctacagc
     3301 tacaccgcta ttgatcactg aaatgtctac atctgacaaa gcacgtgctg tttgggaagc
     3361 atctaattca gaaatgtcta gattttttct attctcggta atatcagaaa cagtgggcgc
     3421 ttgtcctttt gccttatcca ctttgatcaa tccagcagtt tgcaataaca gaagagctct
     3481 gccgccattt gtaacatcat tagggattgc tacttttgct ccgtctttga tatcagctac
     3541 atccttcaaa gtgttagaat aaattcccag cggtgcattg acagtatttc cgatcgatac
     3601 taaatcagtt ccgtgttctt tattgtaatt gtctaaaaag aattgatgtt ggaaagaatt
     3661 caaatcaatc gatccatctg ctaaagccac atttggttga ttgtaatctg taaatttcac
     3721 gtattccaaa ttaatgttct cctttttcaa acggtctttc acgttgtccc atacatctgt
     3781 atcttctcca ataatcccta gttttacgat agtttctttt ttgtcagttg tatctgcttt
     3841 tccttggcta caccctgcca accaaataat tgctacaaat gtaatgacta caaaacgaat
     3901 aatttttttc attttttctc ctccactttc aatgtgtaat ttttttaatc agttgattac
     3961 tgataaattg acttaaaaaa actaagatta gaatcaataa tgtagccaca atcgttacat
     4021 ctgtttggaa tcgattatac cctctcgata tagcaagatt ccctaatccg cctgcaccta
     4081 ctgctccagc catggtagtc agtccgatca cgttgatgat agtcaacgcc gagacccgaa
     4141 tgataccagg caaaccttct aacaaataca cacgtaaaat gataccgatt ggactggttc
     4201 ccatcgcttc tgccgcttcg atcaccccag gatcaacttc tagcagtgcg ttctcgattt
     4261 gacgagcaaa aaacggaaca actccaaaaa tcaatggcac taaagctgct ttcgcaccaa
     4321 tcgtcgttcc aactaagaaa cgagtagtca atgctaaaag agaaagcaag ataatgaaag
     4381 ggatggaacg aatgatattg atcagcttat caagtatttc aaatagcaga cggttagcta
     4441 gtaatccatt agggcgtgtc actactaacg tcacacctaa gatgattcca atcatcccgc
     4501 caatgaatgc tgtccaaaaa gacatatata gtgtttgctt cgtcgcttcg acaaattcat
     4561 ccggaatcaa ataaacattg ggcaaatatg ttttaaagaa atcagtcatt ttatcttcct
     4621 ccttcgatca ctttgatacg actatctaaa tcgttttttt gtaaaatatt tatttttaca
     4681 ccagatttga tcaaataatc caatgctttt ttccgctgtt tggtttctcc agctaaagta
     4741 acgatcaaac tccctaacgg cgtttcttgt aataactcta cattgccata taaaatattc
     4801 gctgttactt gatatttgct gtacagatga gcgattagag gttcgttcgt ctgatttcca
     4861 atataactta attccaccag ccatttattg gcgatctgat cggcaaaagc agaatgggca
     4921 atgatcgttt ctaatgcttg gtcaagatga gtagctgttc gaataaaatc tttggtcaat
     4981 tcttcttcag gattgctgaa gatctggatg ctgctacctt tttcaacgat tcttccatct
     5041 tccataaccg ctaccttgtt gcagatttct ttgacaactt gcatctcatg agtgatcagg
     5101 acgattgtta aacctaactg gcgattcaat ttttttaaca atgcaaggat ctgaagggtc
     5161 gttttcggat caagtgcact ggttgcttca tcacataata ataccttagg ttcattcgcc
     5221 aaagctcgtg cgattgctac tcgttgtttt tgtccccccg acagttgttt aggataagca
     5281 gatgcttttt cttccaaacc gacaagttcc agtagttcat tcactttttg acgacgttcc
     5341 tgtttcgatt ttccagaata ctttaaagaa aaatcaacgt tgtcaaaaat agttcggctt
     5401 tccattagat tgaaatgctg aaagatcata ccgatggcct ttctttcttt tcgcaattct
     5461 ttgggagaga gctgactcag attcgtctga ttgacaatga cttctcctgc tgttggtttc
     5521 tgcagcaaat tcatcacacg aactaacgta cttttccctg cacctgagta accgacgatt
     5581 ccataaacat cgcctttttc aatcgttaaa tctacagaat ctactgcctg tatctctttt
     5641 tctttttgtt tgaaacatac agaaacatct cgcaattcaa tcattaaaat tcctccttat
     5701 ctaaaaaaag cgtcctcaag aaaatgaaaa tgtcattttc ttgaggacgc ttttttgcgt
     5761 gttaccacct catgttcaag ctgtgttcac acacaactcc tcttcaagta cgatcatact
     5821 ctagcaagat atcggtcgca gccgtcatcg ccttacatct atgctcggga tgaattgctc
     5881 gatggccatt ttccaatagt cgttccttgc ttcttctcag ctaccgaagc tctctgtcaa
     5941 aggttcttct atcgtactta ccatttcaat gcaaataata ttcaaaaaaa aagtcctttt
     6001 actaacataa actatgtcag taaaaggacg acgtatcgcg gtaccacctt ttttcggaag
     6061 tttccttccc tcaagcctaa catctcaaaa agagagattg gcgttcgttt taacggtcga
     6121 acagttccga atttgcctac ttatcgacaa attattctcc aaggccattt tcagcttttc
     6181 ttacttgact cttctcacca gccagagcct ctctgcaaag tttccaaact tactttcctt
     6241 ttcaacgaaa tcgatatttt gttgttggga ttaatctaca tgaggaaaac tgaaaagtca
     6301 agtacgaaat tcaaattatt ttttctatat ttatttttct gtttttttat ttaacatttc
     6361 aataacagtt cgaagatctt ttccttccgc aagaagtttc aatttttcct tttcttcgac
     6421 ggtataattt cggacaaaac tggaatcagg tatcaaaaca acgcctaatc ctgctcgtga
     6481 agcagctgtt gctcctacta aagaatcttc cactgcaaag gctgaactag cttctaatcc
     6541 tgttcgttcc aaagctgtca gataaggaat cggtgaaggc ttgttctccg acacttcgtc
     6601 tccgaatgta aacgtgtcca agtaatcagc taatttaaag tgatccaaga tatctgttgc
     6661 tcttttcgta acagtggtcg tagcaatgcc tagtttcata tgacgttctt ttaagtctgc
     6721 caatatttct tttgcatatg gttttaagtg gatggctccg cttgtcagct gttgataaaa
     6781 atattcttca cgcttcgctc ggacttcctg tactttttca gggctacctg ctgctttcac
     6841 taaaatatca aaactttgtt tccagttttt tccgccccaa gcgtcaacga tttcttttgg
     6901 gatatggata tcaaattgct gaaatcccca aagccagcca tcacgatacg ttttttctgt
     6961 gtcaactaac aaaccatcta aatcaaatat tgcacctttc atctatacat taatcctttc
     7021 caaaacaata cacatagttt agcacgactg gtccaaaaag aacagaagca aagaaccagc
     7081 cttctcgttt ataagagttc ttggaatcga cggatataga ttttcttcac agctgtcaca
     7141 agcgccagat aagcgatgac tgtagcaaat aaccataacc agtaattgcc aggaagtggc
     7201 atcaagccta attcagcacc aaaacttgta aaaggaagga cagaaccgac aataattcct
     7261 aatgtagtga taacaaacat ggcaaatgtt gcgttgcttt ggataaatgg tactttcggt
     7321 gtacgcagtg catggagcac taaggtttgt gtccatagtg attcgacaaa ccatcctgca
     7381 tggaataatg cgatgaaaat cactcgctgt gaactatcca atgtatggaa acttccgccc
     7441 actacagcag gacaaataac aaaatacatc aacaagtaag tagtaatatc aaatatcgaa
     7501 cttgttggac caaagtaaac catgaattcc ccaatactag atgcattcca tttttttggc
     7561 tcgtccaaat attctttatc catccgatcc catggcaagg aaatgcagga aacatcatag
     7621 atcagattca aaaacaaaag ttgtaaaggc agcattggta aaaatggcag gaacgtactt
     7681 gcaatcagca cggaaaacat attgccaaaa ttagaacttg ctgtagcctt gatatatttc
     7741 atgatattcc caaaagtttc tcgtccagaa agaaggcctc tttccaaaat cgtcaaatct
     7801 ttttctaaaa ggatcacgtc tgcagattct ttcgcaatat ccacagctgt atctacagaa
     7861 ataccgatat cagccacttt cattgcagga gcgtcattga taccatctcc taaaaatccg
     7921 acagtatgac catttttacg taaagctgtc gtcaaacgtg ctttttgctg aggattcaat
     7981 tttacgaata cttcatggtc ttcagctact tgtgctaatt catgatcact catttccgag
     8041 attttctcac cggtaaccaa ttcattgatc tctagaccta cttgacggca cactgaacgt
     8101 gtaactaatt cgttgtcccc agtcagaact tttacagcta caccatgttc tttcagagct
     8161 ttcaacgctt gtttcgttgt ttcttttggt ggatcaagga aagcaagata accaatcaaa
     8221 accatgtctg actcatcttt gactgaaaat tctccaacga cgcttggatt ggtcttttgt
     8281 gcgacaccaa tcactcgtaa gccatcttca ttaagtgact gtacttttgc aagtacggct
     8341 tcttttcgtt cttttgttaa tggtgtaaca gtaccgccaa gatcaataaa tttagaaatg
     8401 ttcagcattt cttcaatcgc gccttttgtg atcatttgtg ttttaccagc tggatcagca
     8461 accacaacac tcatacgacg acgttcaaaa tcaaaaggaa tttcatccac tttttgataa
     8521 ttgatcttat ctgtatctaa agtttctgtt gcttcatcaa tgatagccac atctaacaaa
     8581 tttttcagcc ctgtttgata gtagctattt agatacgcat ggcgcaaaac acgatcatct
     8641 tcatttcctt cacaatccat atgatattca agaatgattt tatcttgtgt caatgtcccc
     8701 gttttatccg tacataacac atcgattgca ccaaagttct ggatggcatt caaatttttg
     8761 atcactgttc cttttttggc catcacactt gctcctttga ccaaattcgt cgtaacgatc
     8821 attggaagca tttcaggtgt tagaccaact gctacagata gtccaaaaag aaaagcttct
     8881 agccaatccc cttttgtaag cccattgatg acgataactg ctggagccat caatgacata
     8941 aatttgatca gtagcatgga tgttttatgg atgcctaatt caaagcttga ttgaattggt
     9001 ttttcagata gcgtttctgc tacatgacca aatagtgttt catttccaac agaaacaatg
     9061 attccttccg cacttccact gatgacatta cttcccataa agacaagatt ttcgtaactt
     9121 gtttcgcttt gctgatcgtc ttcacatact ttcgcatgct tttctactgg atagctttcc
     9181 cctgtcaatg ctgcttggga aatgaataaa tcctttgcgg acaataaacg catatccgct
     9241 ggtatcatat cccctgctga aagccgaaca agatctccac agacgatttc ttccatagga
     9301 atctctgtgt actttccatt acgttttaca gctgccgtta ctttcacaag tgatttcagt
     9361 ttttcagccg cttgattgga acgtacggac tgaatcaacg tcattgtccc gctgacgata
     9421 accatagtga agataatggc tacaccgaaa agatctttat ctccaggagc tgctaataca
     9481 tattccgtga tgaatgaaat aattcctaat gcgatcaaca ctaatgtaaa tggcgtgatg
     9541 tatgctttca atatttctac aatgaatggt gtttttttgc catatgaaat cgcattttca
     9601 ccgtaatttt ctcttgaacg ttcgatttgt tcttctgtca atccatttgc tgatgcatgg
     9661 aatagttcaa ataattcttg tttcgttttt ccagcaaaag ctgcatagat tttttgtgta
     9721 tctttctttt tttccatctc aatctctcct ttgtgtccaa aagacagctg ttctcgctgc
     9781 ttttggtctt tagctattca tcggatcgat agagaaaaaa ctgaaagggg ctgagaacag
     9841 atagataata gccctggcct ttcctctaga tccttgtttt tcgaatgact gtcatccatt
     9901 tgttctcatc tcctttacta agtaatttta attcatgact tccaatcatt tttcgaatag
     9961 ttatttttcc aattagacca cctccttttt atttttcacc gatggggatt tgcggcaaca
    10021 aaaaaacctc tcgccaaata ctcagcgaaa ggtttgaaaa agcatattaa aaaaagcttc
    10081 tcagatctca tcgttgagtt ttgacactgt acaacgtaaa aagcagatac ctgcttttag
    10141 ctaccttatg aaaagcctta tctcgacaat tcctgttcta cccattggcg tctctcgacg
    10201 tttttgggca gtagcctatg tttgtatagg agcctcacct aacaaatctt attcggtttt
    10261 ccttcgttaa tataacaact aaaaaagagg atgtcaaatc aattttccat gtttttcata
    10321 ctttttttaa aatacacacg ttatattcct gtctcacgcg gttttatttg tctcattttc
    10381 cacctcccgc tataatagaa atatagtagg aaacgaggtg ctgttatgga aagaacactt
    10441 gttattatca agccagacgg cgtgagacgc catttagtcg gaagcatcat ccaacgtttt
    10501 gaagcaaagg gactggccat tgctgaaatg aagtttgaaa ctatgactcc tgaattagca
    10561 aaagaacatt atcagcactt gactgagcgc agtttttttg atgaactgat cgattacatg
    10621 acttccggtc ctgtcgttta tcttgtgctg gtcggcgagg aagtgatcga tatcgtccgt
    10681 aagatggttg gagcaacaaa agctgccgat gctgttccag gtacgatccg aggagactac
    10741 gcgctgccgg ggactgaaaa catcattcac gcttctgatt cccgtgatgc tgcggtaaaa
    10801 gagatcgccc gctttttccc gccattcgat ataaacaaac cgtctgaaaa agcggcgaag
    10861 tgatacaaat tctaaactgc tggtctagtt gctgggttca gcaatggcca gcagtttttt
    10921 ctctaaggac ctccgttgat tctttcctaa catatattcg agcactgtga agaattcttg
    10981 gtagtctttc gtcttttctt cccctaaagc agcagaaatc aatctttgat aataatctgc
    11041 catcaatgtt tcatagatca ctgtacttct ttctttatgt gctaagctcc gtttcatatc
    11101 ttcattcaca ctacgtgcct ttttcaaccg accattttct atataaaacg aagtcaggtt
    11161 cattaaaaaa gtaaagagat actgctcatg attgttcaac tgtgctaatc gtcgcattct
    11221 ttttttgatt ttcaaataat tgttctcaat gaaccgatca ctgaatatcc aaggaaaatc
    11281 agctagaata gatagttcaa attgaccata gtctggtatc tgcatcaagt attcttcaat
    11341 gattcggcat tcataacgta aaaattcaaa ttctgtctca gatacttctg ttttttcgac
    11401 catgtgaaga ttcaaaacca aataatacag atcttctgtt ttcttaaaat gcctacggtt
    11461 attgctgatc tctttataag gatcaaagct gtcttcttgt acccgatcta gcattcgtct
    11521 ttttttcttt aactttattg gttcatccag ctggtttcgc atccattcat attctgcaag
    11581 tgtcatgttc attcgctcta aaaatgatct caatgttaca aatgacattt ttttcactga
    11641 atttgtctca atcccgacta gagaagtctt aaaacagatt ccttccgcta attgggactg
    11701 tgtcaacttc ttgttgactc gaagtttctt gatcaattca ccatcataca taatagttct
    11761 cctttttaat ttaaattttt ccacattcaa taaatagata cgttaaaaag gaaaaataca
    11821 cgaaaaaaat aaaaaaatgt ttttttcata aaaaatacca accttcaagc attagaatgt
    11881 tgtctaacta ctgaaggttg gtttgattgt ttattgatta tttttttgct gttcaacgtc
    11941 tgttcttgtt actggatata agttggttgt tgttttatta ccattttttg aaaagacact
    12001 tgtcgaatgt tcgccttttt gcttttcgat tgcttcatta cgttccgctt catttttata
    12061 gtcatatttt ttcggatcaa tcgtctcaaa tccgtttggc acataaaacc gcaagagatt
    12121 ttcctgattc agcttatctg aaagacttaa cgcagtcttg actttttcct gatctttgga
    12181 gatttcctca tcgattcctg ctgctttcgt atcgatgatt tctcctgtct gattattgta
    12241 agcttttcct cctaggacgg tgtatttggg tgtcacaaag ttcccatttc gaaaagcaac
    12301 tacttgatca tgctgagaag ataataagtc tgtaccaaaa tgaagataat ctttatcatc
    12361 gattcccaat agatgtagta atgtcggcaa aacatcgatt tctccaccgt attcatgatt
    12421 gactgtccct ttagtataac caggcatatg gatcatcaat ggcactcgtt gcatctgtgc
    12481 gttgtcaaat tcatcccatg tatctggatc tttaccaaga gcgcttgcta aatctttatt
    12541 atctgtattc gagatcccaa aatgatcccc gtaaatcaca aagattgaat tttggtaaat
    12601 accagatttt ttcaaatacg taaaaaattg ttccaatgat tgatccagat aatgtgccgt
    12661 tcgaacataa ttatctactg tgctattgcc agtattcaaa gatggaaagt cgaaattctt
    12721 gtcatccgta taataaggcg tgtggttggt tacggaaaga aatttcgtgt aaaacggctg
    12781 ttgtagatgc tcaagatatt gggcagattc tctgaataaa tctttatcta atatcccata
    12841 acctaacgtt tcgtcggatt catcaaaata agatcgatca aagaaattgt cataacctaa
    12901 gtttttatat acatgatctc tattccaaaa actagctaca ttcccatgga aaacagcgct
    12961 tgtatagcct tgcttttgtc caaggatcgc tggtgcggct tgaaagacat tgtctgaccc
    13021 aagttctgtg aataatgagc cttgaggtaa accaaatgtg ccagtttcca acatattttc
    13081 agcatcactt gtctttccct gtcctacttc atgaaagaaa ttgtcaaagc tgatcgttgc
    13141 ttgattctgg aaaatactat ttaaaaacgg tgtgacttct tgtccgtcta ccttcatatt
    13201 aatcaaaaac tgctggaaac tttctaaatg gagaacgatc acatttttcc ctttagcgat
    13261 cccaaatgtt tcgggatttg gctctgcata atgtttcttt gtataatcta aaacttcatc
    13321 aatcccatta ctgcttgcat gcgcgcgaac actgctagtc attcctgttt tgattccgtc
    13381 ataaatagta tacgcatcga ttcctagata tttgacaata tatgaacggt caaatgttcg
    13441 ctgcagcaat tgtggacggt tggcttcgct cagcgctaga tttcctgaaa aaataagccc
    13501 tgaaagacag gtaacagcga tagccatcgg tttgccgaca gggttgcttt tgataggtat
    13561 tttcttgacc ttcaaccaaa ccagtagccc aatgaacaca gcgatatcca gccagtagat
    13621 gacatcatgg ggcttcatca aagaaaagga gcttcctgac aatccttgcg acactttcga
    13681 aaagcctaat acagatttga ctgtaatgaa atctgtgaat tcccgataaa aaataatatt
    13741 caagtacaac aaaagcgtat ttaaaatatc aatgatcaaa agaatagcta acgctggctt
    13801 tggcttttta atatacaaag aaaggccaaa aaacaataag gtagtcgcaa ttgggttgat
    13861 ccacaagata aagtactgga tcgtaccttc cacacctaat gaaaaatctg catagtaggc
    13921 aatgatcgtc ttcagccaga aaaagaaaac agctgtcaaa acgattgcta aacgattttg
    13981 gcacaatttt ttaagttgtg tcacgtatat cacttctctc tattcacatt ttttcttatt
    14041 ttgctcctga aaaatgaaaa tttcctaaaa aagttgttat cttaagattt ttttattctt
    14101 tctaaagatt attccgtcca cttttcacag cataaaaccg ctgcgatgta agcgattaaa
    14161 ctaatgaaga gataaaagtc ttgtggtgac cgcttcactc cacggtattc aaaagccagt
    14221 ttctcggtat tcgtacaaaa aaagaggctg tgacaaaatt cttgtcgcag ctccttattt
    14281 cttgatgcag gacagctttt tcacaacttc ttccttaaac ggtgttctcc tgccaactcc
    14341 tcggccacaa gtcacaatat ttataaaaca tgagaagctg ttttttgaaa ttgttccttg
    14401 tggctcagag ttaaacggca ggctcaagac ctcttgatac acggtgttca atcagctgac
    14461 cctcggtatt agattatgtc aggacgctaa ttttacaacc tcttggtaaa cggtgttcaa
    14521 aagcttgcat ctgcggtaat aagcccaacc aaacgaaaaa tataaggagc tattttttga
    14581 aattgctcct tgtggctcag agttaaacgg caggctcaag acctcttgat a
//
LOCUS       DAFBVQ010000064        14625 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.067, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000064 DAFBVQ010000000
VERSION     DAFBVQ010000064.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.067"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            4..816
                     /locus_tag="LLC22_002256"
     CDS             4..816
                     /locus_tag="LLC22_002256"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294134.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="isoprenyl transferase"
                     /protein_id="HBK5435511.1"
                     /translation="MLRFFPQKNKYIQEKSEFQFNTDGPIPQHIAIIMDGNGRWAQNR
                     RLPRVAGHKEGMETVKKVTKKASRLGVKVLTLYAFSTENWKRPKDEVSFLMQLPVDFF
                     DTFVPELIKENVKVHVMGYENVLPEHTQDAVRRAIEQTKNNTGMVLNFALNYGSRAEI
                     VTAVQEIAEEVAKGEIHAEEIDDELIAKHLMTGFLPKELQDPELMIRTSGEERISNFL
                     LWQIAYSELYFTKALWPDFDGAHLEEAIASYQNRDRRFGGVKKTEDEKGDQS"
     gene            813..1613
                     /locus_tag="LLC22_002257"
     CDS             813..1613
                     /locus_tag="LLC22_002257"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphatidate cytidylyltransferase"
                     /protein_id="HBK5435512.1"
                     /translation="MKQRVITAAVALVLFIPIIWIGGIAVELTAAILAVVGVYELFRM
                     KGLTLLSFEGVLSAVGAVLLVLPKERWFFFLPENVSTFMLFYLIVMILLGTSVISKNT
                     YTIDEAGFPVLVSLYVGIGFQNFVNARTESLAVLIFGLFIVWATDIGAYMVGRRYGQH
                     KLSPDISPNKTIEGALGGIGSAVVVAFLYLLLYPAKELFNHGMFVMLLMTIIFSAVGQ
                     FGDLVESAIKRHYDVKDSGNILPGHGGILDRFDSLLFVFPIMHLFGII"
     gene            1774..3042
                     /gene="rseP"
                     /locus_tag="LLC22_002258"
     CDS             1774..3042
                     /gene="rseP"
                     /locus_tag="LLC22_002258"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306441.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RIP metalloprotease RseP"
                     /protein_id="HBK5435513.1"
                     /translation="MKTILTFIIVFGILVIVHEFGHFFFAKRSGILVREFAIGMGPKI
                     YGHQAKDGTTYTLRLLPIGGYVRMAGNGDDETEMAPGMPLSLLLNSDGIVEKINLSKK
                     IQLTNAIPMELSRYDLEDELTITGYVNGDETEVVTYPVDHDATIIENDGTEIRIAPKD
                     VQFQSAKLWQRMLTNFAGPMNNFILAIVLFIILAFMQGGVQVTNTNRVGEIMPNGAAA
                     EAGLKENDEVVSVDGKEIHSWNDLTTVITKNPGKTLDFKIEREGQVQSVDVTPKSVES
                     NGEKVGQLGIKAPMNTGFMDKIIGGTRQAFSGSLEIFKALGSLFTGFSLDKLGGPVMM
                     YQLSSEAANQGVTTVISLMALLSMNLGIVNLLPIPALDGGKLVLNIFEGIRGKPLSQE
                     KEGILTLAGFGFLMLLMVLVTWNDIQRFFF"
     gene            3110..4819
                     /locus_tag="LLC22_002259"
     CDS             3110..4819
                     /locus_tag="LLC22_002259"
                     /EC_number="6.1.1.15"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723221.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="proline--tRNA ligase"
                     /protein_id="HBK5435514.1"
                     /translation="MRQSKMLIPTLREVPNDAEVLSHQILLRAGYIRQVSAGIYSYLP
                     LANRVLEKLKRIMREEFEKIGAVEMLMPAILPAELWEESGRYETYGPNLYRFKDRNDR
                     KMILGPTHEETFTDLMRNEINSYKKLPLNLYQIQPKYRDEKRPRFGLLRGREFIMKDA
                     YSFHATEESLDETYKDYEKAYTEVFKRCGLEFRSIIGDGGAMGGKDSKEFMAISEIGE
                     DTICYSTESDYAANLEMATSYYVSKKSHETQLELEKVATPNVKSIDEVADFFSVEPQK
                     IIKSVLFIADEQPVLVLVRGDHEVNDVKLKNFLSADFLEEATEEEAQKYLGAEFGSVG
                     PVGVSDDVKVYADRYVQDLANAITGANETGFHYKNVNPERDFTVLSYEDLRFVQEGDP
                     SPDNNGVLAFTRGIEIGHIFKIGTRYSESMGATVLDENGREKFVIMGCYGIGVSRLLS
                     AIVEQHSDEQGINWPKGIAPFDLHIVQMNLKDEYQTSLTNELEEAMTKAGYEVLVDDR
                     NERAGVKFADSDLIGCPIRITVGKKAVDGIVEVKIKKTGEMVEVRKEELANTLPILLN
                     QGE"
     gene            5031..9389
                     /locus_tag="LLC22_002260"
     CDS             5031..9389
                     /locus_tag="LLC22_002260"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PolC-type DNA polymerase III"
                     /protein_id="HBK5435515.1"
                     /translation="MSEKRDLFEKLLEQIQLEEAEKNHPLLTAGEMDSVVVHRKSRLW
                     EFTLHFSKILPIMLYRSLTQHLTIAFKDIAQVKLNILADDQTFDEQLLQDYWAQALEN
                     QQCDTPLAQQVLKTQVPVIKDRKVILPIDSTGAISYLKQQYLPLVEELFVSYGFPKFR
                     IEPEVDEQQAERVLKLFEERKQEQAEAFMKQAAESLVVHEQKKKERKEQSPALEGPIH
                     IQLGRNIPADEPTTPMISIVEEERRVTLEGYVFDKEVRELRSKRKILTLKITDYTSSF
                     IVKKFSNGEKDEQVFDAISVGSWLKVRGSIQEDTFVRDLVMNAQDIIEVKHTPRKDYA
                     PEGEKRVELHVHSNMSTMDATNSISDLVAQAGKWGHRAIAITDHGGAQAFPEAHSAGK
                     KAGVKILYGVEANVVDDGVPIAYNDAHEALSEATYVVFDVETTGLSAVYDTIIELAAV
                     KMYKGNVIESFDEFIDPGHPLSRTTVDLTGITDGMVRGSKSEEEVLRMFLEFSKDTIL
                     VAHNAAFDMGFLNTSYARYGIPEAANPVIDTLELARYLYPQFKRFGLGVLSKKFGVSL
                     EQHHRAIYDAEATGHLAWIFVKEAMDNHNMLYHDQLNEHIGEGDSYKRARPFHVTILA
                     KNQAGLKDLFKLISMSNVEYFERVPRIPRSQLKKMRENLLIGSACDKGEIFEAMMQKG
                     VEEARNRAKFYDYIEVMPKAVYAPLIEQELVKNEHDLEEIIQNLVEIGKSLDKIVVAT
                     GNVHYLNEEDAIYRKILINSMGGANPLNRHSLPDVHFRTTDEMLTAFHFLGEETAKEI
                     VVENTNKIADICEEVIPVKDELYTPKIPGSEDEISELSYTKAKQMYGDPLPEIIQKRL
                     KKELNSINGNGFSVIYLIAQKLVHKSNEDGYLVGSRGSVGSSFVATMTGITEVNPLAP
                     HYYCPECQYSEFFEDGTYGSGFDMPEKQCPKCGARLNKDGHDIPFETFLGFHGDKVPD
                     IDLNFSGDYQAEAHNYTKVLFGEDYVYRAGTIGTVADKTAYGYVKGYERDNNLQFRSA
                     EVDRLAKGATGVKRTTGQHPGGIIVIPDYMDVYDFTPIQYPADDQNSEWKTTHFDFHS
                     IHDNVLKLDILGHDDPTVIRMLQDLSGIDPQTIPTDDPEVMRIFAGPEVLGVSQEQIY
                     SKTGTLGIPEFGTRFVRGMLEETHPTTFAELLQISGLSHGTDVWLGNAEELIRRGDAT
                     LAEVIGCRDDIMVYLIHAGLDSGMAFKIMETVRKGQWNKIPDELRETYLSAMKENNVP
                     DWYIDSCSKIKYMFPKAHAAAYVLMALRVAYFKVYFPILYYCAYFSVRADDFDLVSMC
                     KGKDAVKQAMKEITDKGLDASVKEKNQLTVLELANEMLERGFKFGMIDLYKSDAVNFV
                     IEGDTLIAPFRAVPSLGTNVAKQIVEARKDGPFLSKEDLATRGKVSKTLIEYMNDNGV
                     LKDLPDENQLSLFDML"
     gene            9534..10007
                     /gene="rimP"
                     /locus_tag="LLC22_002261"
     CDS             9534..10007
                     /gene="rimP"
                     /locus_tag="LLC22_002261"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome maturation factor RimP"
                     /protein_id="HBK5435516.1"
                     /translation="MSSVVETVTEMVTPILDEQNFELVEVEFVKEGKSWFLRVFIDKE
                     GGIDIEECAFVSEKLSEKLDAADPDPIPQAYFLEVSSPGAERPLKKESDYEKALGDYV
                     HVSLYQPVDGEKQYEGFLQSFDAEQLTLKIRIKTREKELTFDRKNIAKARLAIQF"
     gene            10030..11205
                     /gene="nusA"
                     /locus_tag="LLC22_002262"
     CDS             10030..11205
                     /gene="nusA"
                     /locus_tag="LLC22_002262"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription termination/antitermination
                     protein NusA"
                     /protein_id="HBK5435517.1"
                     /translation="MSKEMLNALDALEAEKGISKEIVIDALEAALVSAYKRHYGQAQN
                     VEVEFDQKKGKIHVYAVKEVTEEVMDSQLEVSLKDALLINPAYEIGDTIRFEVTPKDF
                     GRIAAQTAKQVILQRVREAERTIIYNEFSAYEKDIMQGIVERQDKRYIYVNLGKIEAV
                     LSKQDQMPNEFYQPHDRIKVYVSRVENTSKGPQVFVSRSHPDLLRRLFEQEVPEVYDG
                     IVEIVSIAREAGDRSKVAVRSNDPNIDAVGTCVGPKGQRVQAIVNELKGENMDIVEWN
                     EDPAVFIANALNPAQVMDVIFDETNPKACTVVVPDYQLSLAIGKRGQNARLAAKLTNH
                     KIDIKSESDMTEFYENQEQQKETEELHDEAIVQSDLTDDEYETIAFNNETVEEKPEA"
     gene            11227..11520
                     /locus_tag="LLC22_002263"
     CDS             11227..11520
                     /locus_tag="LLC22_002263"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875920.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxR family protein"
                     /protein_id="HBK5435518.1"
                     /translation="MKQRKIPLRKSVVSGEMKPKKEMVRITRSKEGEVSIDPTGKMPG
                     RGAYVSLEPEEVQQAWDKKILDRVLETTLTDEFYQELLDYVTHQKARKELFGK"
     gene            11517..11828
                     /locus_tag="LLC22_002264"
     CDS             11517..11828
                     /locus_tag="LLC22_002264"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344352.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YlxQ-related RNA-binding protein"
                     /protein_id="HBK5435519.1"
                     /translation="MNTVNRQKAMNLIGLAMRAGKLITGEELTIAEIRKQKAKLVFVA
                     TDASENTRKKIKDKSSYYEVPCFELFSEAEITQMIGKPRKVFGIMDAGFAKKTKELIE
                     G"
     gene            11841..14147
                     /gene="infB"
                     /locus_tag="LLC22_002265"
     CDS             11841..14147
                     /gene="infB"
                     /locus_tag="LLC22_002265"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297399.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="translation initiation factor IF-2"
                     /protein_id="HBK5435520.1"
                     /translation="MGNKRIYELAKELKKSSKDVVEKAQQLGIDVKNHMGAITSNDEK
                     KLQQAFKNPSTKQQAAQQASRKPANQQPNDQRKKETTNNQQKNKNNRSYQDRGQGSGQ
                     VNQGKKPTTNQNNTGNTSSQNRQGTSQGGNQNRTNNNNKPNNNNRGKFNNNNRNRYNK
                     KGKKGKQQQSTKPAVPPRKFRELPDVLEYTEGMNVADIAKKIHREPAEIIKKLFMLGV
                     MVNQNQALDKDTIELLATDYGMEPQEKVQVDIADIDKFFEAEEVDPDKLVSRPPVVTI
                     MGHVDHGKTTLLDTLRHSRVTSGEAGGITQHIGAYQIDIDGKPITFLDTPGHAAFTSM
                     RARGASITDITILVVAADDGVMPQTVEAINHAKAAGVPIIVAVNKIDKPGANPQHVMQ
                     ELSEYELIPEAWGGETIFVEISAKFGQNIEELLEMILLVAEVEDLKADPTQRAIGTVI
                     EARLDKGKGPVSTLLVQEGTLHVGDPIVVGNTYGRVRVMTNDLGRRDKEAGPATPVEI
                     TGLNDVPQAGDRFVVFEDEKTARAAGEERAKRALLENRAATSRVTLDNLFESLKEGEL
                     KEVNVIIKADVQGSAEALAASLKKIDVEGVRVKIVHSAVGAINESDVTLAAASNAIII
                     GFNVRPTPQAKVQADTEEVDIRLHRIIYKAIEEIETAMKGMLDPEFEEKITGQMIVRE
                     TFKVSKVGTIAGAYVTEGYIRRDSGVRVIRDGIVIYEGQLASLKRFKDDVKEVKMGYE
                     CGAMIEKFNDIKVDDVIEGFIMEEVKND"
     gene            14174..14521
                     /gene="rbfA"
                     /locus_tag="LLC22_002266"
     CDS             14174..14521
                     /gene="rbfA"
                     /locus_tag="LLC22_002266"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010735198.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosome-binding factor RbfA"
                     /protein_id="HBK5435521.1"
                     /translation="MANYRDRRVGQEILKEVNDILRKKVRDPRVENVTITDVKVTGDL
                     QQATIYYSILSDLASDKKTAQDGLNKASGLIRRELGHNLSIYKTPELFFELDESVVYG
                     NHIDELLRDLNKD"
BASE COUNT         4984 a         2598 c         3255 g         3788 t
ORIGIN      
        1 agaatgttac gtttttttcc gcaaaaaaac aaatatattc aagaaaaaag cgaatttcaa
       61 tttaataccg atggaccaat tcctcagcac attgccatca tcatggacgg caatggtcgt
      121 tgggcgcaaa accgtcgttt gccacgagtt gctggccata aagaaggcat ggaaacagta
      181 aagaaagtca caaaaaaagc atcaaggctt ggagtgaaag tgttgacgct ttatgccttt
      241 tcgactgaaa actggaagcg accaaaagat gaagtaagtt ttctcatgca actacctgtc
      301 gacttctttg atacgttcgt accagaattg attaaagaaa atgtcaaagt tcatgtcatg
      361 ggttatgaaa acgtattgcc agaacatacg caagatgctg taagacgtgc aattgagcaa
      421 acaaaaaaca atactggaat ggtattgaat tttgctttga attatggaag tagagcagag
      481 atcgtgactg ctgtccaaga aattgccgaa gaagtagcaa aaggagaaat acacgcagaa
      541 gaaatcgatg atgaattgat tgctaagcat ttaatgacag gtttcttgcc taaagagtta
      601 caagatcctg agctgatgat ccgtacaagt ggagaagagc gaattagtaa ttttctgtta
      661 tggcagatcg catatagtga gctgtatttt acaaaagcgc tttggcctga ttttgatggt
      721 gcgcatcttg aagaagcaat cgcctcttat caaaatcgag accgtcgatt cggcggtgta
      781 aaaaaaacag aagatgagaa aggggatcag tcatgaaaca acgtgtgatc acagcagctg
      841 tggcgctagt cttgtttatt ccgattatat ggatcggagg catagcggtt gagcttacag
      901 cagcaatctt agcggtagta ggagtttacg agctgttccg gatgaaagga ttgacactct
      961 taagttttga aggagtttta tccgccgttg gtgcagtgtt acttgttttg ccaaaagaaa
     1021 gatggttttt ctttcttcca gagaatgtaa gtacatttat gttattttat cttatagtta
     1081 tgattctttt aggaacatca gttatttcta aaaatacgta tacgattgat gaagcaggtt
     1141 ttcctgtgct tgtcagcttg tatgtgggaa taggtttcca gaattttgtc aatgcacgaa
     1201 cagaaagctt ggctgttttg atatttggtc tatttattgt ttgggcaact gatatcggag
     1261 catatatggt tggtcgacgt tatggtcagc ataagttaag tcctgatatt tcgcccaaca
     1321 aaacgattga aggtgcgctc ggtggtatcg gtagtgctgt tgtagtcgca tttctttatt
     1381 tattgctata cccagcaaaa gaactattca atcatggtat gtttgtcatg cttctgatga
     1441 cgattatttt ttcagcagtc ggacaatttg gtgatttggt cgaatctgca atcaaacgtc
     1501 attatgatgt gaaagactcg ggaaatatct taccaggcca tggtggaatc ttagaccgtt
     1561 tcgacagttt gctgtttgta tttcctatca tgcatttatt tggcattatt tagtaagtat
     1621 acctgcgttt ctttgtgaat ttcataaaag acgcaggttt ttatttttca ttatattgat
     1681 actattggtg tctttggtat actatggtaa aattatagtg ttttatcgtt gttttataaa
     1741 aaacacaaaa aacaagtaaa ggagaaaaaa gctatgaaaa cgattctgac atttatcatc
     1801 gtttttggta tattagtgat tgttcatgag tttggtcatt tcttctttgc gaaacgatca
     1861 ggaatcctcg tccgcgaatt tgctatcggt atgggtccga aaatttatgg gcatcaagca
     1921 aaagacggga caacatatac gcttcgccta ttacctattg gcggttatgt tcgaatggca
     1981 ggcaatgggg atgatgaaac agaaatggca ccaggaatgc ctctttctct tttactaaat
     2041 tctgacggca tcgtagagaa gataaattta agtaagaaaa tccaattgac aaatgctatc
     2101 ccgatggaat tgagccgtta tgatttagaa gatgagctga ctatcactgg ttatgtgaat
     2161 ggagacgaaa cagaagtagt aacctaccct gttgatcacg atgcgacgat tattgaaaac
     2221 gacggaacag aaatcagaat tgcgccaaaa gacgtacagt tccaatcggc taaattgtgg
     2281 cagcgtatgc tgaccaactt tgctggaccc atgaataact ttattttggc aatcgtgtta
     2341 ttcatcattc tggcatttat gcaaggtggt gttcaagtga cgaacactaa tcgcgtagga
     2401 gagatcatgc ctaatggagc tgcggcagaa gcaggcttaa aagaaaatga tgaggtagtc
     2461 agtgtggacg gaaaagaaat ccattcatgg aatgatctga caacagtcat tacgaaaaat
     2521 ccaggtaaaa cattagactt taagatcgaa cgagaaggtc aggtgcaatc tgtcgacgtg
     2581 acaccgaaat ctgtagagtc aaatggcgaa aaagttggcc aacttggtat aaaagcccca
     2641 atgaatacag gttttatgga taagatcatt ggagggacgc gtcaagcttt cagcggttca
     2701 ttggaaattt tcaaagcctt aggatcacta tttacaggtt tcagtttaga taaattaggc
     2761 ggacctgtca tgatgtacca attgtcttca gaagcagcaa atcaaggtgt aacaactgtt
     2821 attagtttga tggcgcttct ttcaatgaat ctcggaatcg tcaatctgct tccgattcct
     2881 gccttagatg gcgggaaatt agtcttgaat atttttgaag ggattcgcgg gaaaccatta
     2941 agtcaagaaa aagaaggaat attgacatta gctggctttg gatttttaat gttgttgatg
     3001 gtgctagtta catggaacga tattcaacga ttctttttct agaaaaagtt gacaaatagg
     3061 gtataataac aaacgataac tattttgagg aaataaagga gtatatagaa tgagacaatc
     3121 aaaaatgttg attccaacat tacgcgaagt tccaaatgat gcagaagtat taagccatca
     3181 aatcttgcta agagctggat atatccgcca agtatcagcg ggtatttatt catatctgcc
     3241 attagcaaat cgtgtattgg aaaaactgaa acgcattatg cgggaagaat ttgaaaaaat
     3301 cggagcggta gaaatgctga tgcctgccat cttgccagca gaactttggg aagaatccgg
     3361 gcgttacgaa acatatggac caaacttgta tcgtttcaaa gaccgcaatg atcgaaaaat
     3421 gatccttgga ccaactcacg aagaaacttt tactgatttg atgcgtaatg aaatcaattc
     3481 atataagaaa ttacctttaa atctttatca aatccaacct aaatatcgtg acgaaaaacg
     3541 acctcgcttc ggtttgcttc gcggaagaga gtttatcatg aaagatgcat attctttcca
     3601 tgcaacggaa gaaagtttgg acgagacata taaagattac gaaaaagcct ataccgaagt
     3661 attcaagcgt tgtggcttag aatttcgctc gatcatcgga gacggcggcg caatgggcgg
     3721 gaaagactca aaggaattca tggcgatctc agaaatcggg gaggatacga tctgttattc
     3781 gactgaaagt gattatgctg caaacttgga gatggctaca agctactatg tatcaaaaaa
     3841 atcgcatgaa acacagcttg aattggagaa agtagctaca cctaacgtaa aatcaattga
     3901 cgaagtagca gatttctttt ctgttgaacc tcaaaaaatc atcaagtctg tattgttcat
     3961 tgcggatgaa caacctgtcc ttgttttggt acgtggagac catgaagtca atgacgtaaa
     4021 actgaaaaac tttttatctg ctgacttttt agaagaagca acagaagaag aagcacaaaa
     4081 atatctaggt gcagagtttg gttctgtcgg accagtcggt gtttcagatg acgtaaaagt
     4141 atatgcagac cgttatgtcc aagatttagc gaatgccatt actggagcga acgaaacagg
     4201 attccactat aaaaatgtga atccagaacg cgatttcact gtgctttctt atgaagatct
     4261 tcgttttgta caagaaggag atccttcacc agacaacaac ggtgttcttg cctttactcg
     4321 aggaatcgaa atcggacata tattcaaaat cggcactcgt tacagtgaat ctatgggagc
     4381 aactgtacta gacgaaaatg gacgagaaaa atttgtgatt atgggctgtt atggtatcgg
     4441 tgtaagtcgt ttattatcag caatcgtaga acaacattca gatgaacaag gaatcaattg
     4501 gccaaaagga attgcgccat ttgatctgca tatcgtccaa atgaatctaa aagacgaata
     4561 ccaaacaagc ctgacgaatg aactagaaga agcgatgaca aaagctggct atgaagtact
     4621 ggttgatgac agaaatgaac gcgcaggagt gaaattcgcg gattctgatt tgattggctg
     4681 tccaatcaga atcactgtcg gtaaaaaagc agtggatgga atcgtagaag tgaaaatcaa
     4741 gaaaactggc gaaatggttg aagtacgtaa agaagaattg gcgaatactt taccaatcct
     4801 cttgaaccaa ggcgaataat aagcgttaaa acacagaaaa taaaaatagc tgaatcagct
     4861 gtttttgaca atctgatgat tcgcttttaa aattggaact gcgatttgaa tcgcagttcc
     4921 aattttttaa tgtaaaactc agaaaaaacg agtatactaa aaggtactga aaaagaagag
     4981 gataagatgc gatcaattgc attgtttctc atcagaaagg gcgtatatct ttgtcagaaa
     5041 aacgagattt atttgaaaaa ctgttggaac aaatccaact agaggaagca gaaaaaaatc
     5101 atccactgct tactgctggt gaaatggata gtgtagtggt ccatcgtaaa tcgcgtttat
     5161 gggaatttac gctacatttt tccaaaattt tgcctattat gctatatcgg tcattgactc
     5221 agcatctgac tatcgctttt aaagatattg cacaagtcaa actgaatatc ttagcagatg
     5281 accagacatt cgatgaacag ctcttgcaag attactgggc ccaagctttg gaaaatcagc
     5341 aatgcgatac accactagca cagcaagtat tgaaaacgca ggtacctgtg ataaaagatc
     5401 gtaaagtcat cttgccaatc gacagtacag gagctatttc ttatttgaag caacaatact
     5461 tgccattagt agaagagttg ttcgtcagtt acggattccc aaaatttcgt atcgaaccag
     5521 aagtggatga gcagcaagcg gaacgagtat tgaaactttt tgaagaacgc aaacaagaac
     5581 aggcagaagc ctttatgaag caagcagctg aaagtctagt tgtccacgaa caaaagaaaa
     5641 aggaaagaaa agagcaatcg ccagctcttg aaggacccat ccacatccag ctaggacgaa
     5701 atattccagc cgatgaacca acgacaccaa tgatcagtat cgttgaagaa gaacgaagag
     5761 tcacacttga ggggtacgta ttcgacaaag aagtcagaga actacgttca aaacgcaaga
     5821 tcttgacttt gaaaatcaca gattatactt catcatttat cgtcaaaaaa ttctcgaacg
     5881 gcgaaaaaga tgaacaagta tttgatgcga tcagtgtcgg tagctggtta aaggtacgag
     5941 gaagtattca agaagatacg tttgtccgtg atttggtcat gaatgcgcaa gatatcatag
     6001 aagtcaaaca tacacctcgc aaagattatg ctcctgaagg ggaaaaacga gtagagcttc
     6061 atgttcatag caatatgagt acgatggatg caacaaacag catctctgat cttgtggcac
     6121 aagcagggaa atggggacac cgagctatcg ccattacaga ccacggtggt gcgcaagcct
     6181 ttccggaagc acatagtgct ggaaaaaaag caggtgtgaa aatcttatac ggcgtggaag
     6241 cgaatgtcgt agatgatggt gtcccaattg cttataatga tgcacatgaa gcattgagtg
     6301 aagccacata tgtcgtattt gacgtggaaa cgacaggatt gtctgcagta tatgacacga
     6361 tcatcgagct agccgcagtc aaaatgtata aaggaaatgt gatcgaaagc tttgatgaat
     6421 ttatcgatcc aggacatcct ttgtcacgaa caacggtaga tctgactggt atcacggatg
     6481 gaatggttcg aggatcaaag tcggaagaag aagtattgcg gatgttcctt gaattttcaa
     6541 aagatacaat tttggtagcc cacaacgcgg cttttgatat ggggttcttg aatactagct
     6601 acgcaaggta tggtattcct gaagcggcca atccagtcat tgatacgttg gaattagcta
     6661 gatatctgta tcctcaattc aaacgtttcg gattaggtgt gttatctaaa aaatttggtg
     6721 tcagcttgga acagcatcac cgagcaatct atgatgctga agcaactggt cacttagcat
     6781 ggatctttgt gaaagaggca atggacaatc ataacatgct ttatcatgat cagctaaatg
     6841 agcatatcgg agaaggagat tcttacaaaa gggctcgacc tttccatgta acgattttag
     6901 caaaaaatca ggcaggactg aaagatttgt tcaaactgat ttcaatgtcg aatgtcgaat
     6961 acttcgaacg cgtcccacga ataccacgct cccaattgaa aaagatgcgt gaaaatctat
     7021 tgatcggctc agcttgtgat aagggagaaa tattcgaagc catgatgcaa aaaggggtag
     7081 aagaggcaag aaaccgagca aaattctacg attatattga agttatgcca aaagcggtct
     7141 atgcgccttt gatcgagcaa gaattggtaa aaaatgaaca tgatttggaa gaaattatcc
     7201 aaaatttggt agaaatcgga aaaagtttgg ataaaatcgt tgttgcaaca ggtaatgtac
     7261 attatctgaa cgaagaagat gccatttacc gaaaaatttt gatcaattct atgggcggag
     7321 cgaatccgtt gaatcgtcat agtttgccgg atgtccattt ccgaacaacc gatgagatgc
     7381 taactgcatt tcacttttta ggggaagaaa cagcgaaaga gatcgtagta gaaaatacga
     7441 ataaaatcgc agatatctgc gaagaagtga ttccagtcaa agatgaactt tatacaccga
     7501 agattccagg ttcagaagat gaaatatcag aattgagtta cacaaaagca aaacaaatgt
     7561 acggagatcc gttacctgag atcattcaaa aacgattaaa aaaagagttg aattctatta
     7621 atggtaatgg cttctcggtt atttatctga tcgcccaaaa actagtgcat aaaagtaatg
     7681 aagatggcta tctagtaggt tcacgtggct ctgttggctc tagctttgtt gcgacgatga
     7741 caggaatcac tgaagttaat ccgttagccc ctcattatta ttgtccagag tgccaatatt
     7801 ccgagttttt tgaagatggt acgtatggtt ctggatttga catgccagaa aaacaatgtc
     7861 caaaatgtgg tgcacgctta aacaaagacg gtcatgatat tccatttgag acatttttag
     7921 gattccatgg agacaaagtg cccgatattg atttgaactt ctcaggtgat tatcaagcag
     7981 aagcccataa ctatacgaaa gtattgtttg gcgaagacta tgtttaccgt gccggaacga
     8041 ttggtacagt cgccgacaaa acagcatatg gctatgtaaa aggatacgaa agggacaata
     8101 atctgcagtt tcgaagtgca gaagtcgaca gattagcaaa aggcgctact ggagtcaaac
     8161 ggacaaccgg ccagcatcca ggggggatca tcgttattcc cgattatatg gatgtctatg
     8221 attttacgcc gatccaatat ccagcagacg atcaaaattc ggaatggaaa acgactcatt
     8281 ttgattttca ctcgattcac gataatgtat tgaaattaga tattctaggg catgatgacc
     8341 caactgttat tcggatgctt caagatttat cagggatcga tccacaaacg atccctacgg
     8401 atgacccgga agtgatgcgg atatttgccg gtcctgaagt acttggagta agtcaggaac
     8461 aaatttattc caaaacaggg acattaggta ttccagaatt cggcactcgt tttgttcgag
     8521 ggatgctaga agaaacgcat cctacaactt ttgcagaact actgcaaatt tccggactat
     8581 ctcatggtac agacgtatgg ttaggaaatg cggaagaatt gattcgacga ggagatgcga
     8641 cactggcgga agtaatcggc tgtcgtgatg atattatggt ttatttgatc catgctggat
     8701 tagatagcgg gatggcattt aaaatcatgg aaactgttcg taaaggacaa tggaacaaga
     8761 tccctgatga attgcgagaa acctatctat cggcgatgaa agaaaataat gtgcccgact
     8821 ggtatatcga ttcttgttca aaaatcaaat atatgtttcc gaaagcccat gctgcagctt
     8881 acgtattgat ggctcttcgt gtcgcttatt tcaaggttta tttccctatt ttgtattact
     8941 gtgcatactt ttctgtacgt gcagacgact ttgatctagt ctccatgtgc aaaggaaaag
     9001 atgctgtgaa acaagcaatg aaagaaatca cggacaaagg attagatgct tccgtaaaag
     9061 aaaagaatca actgacagtg ctggagttag ccaatgaaat gctggaacga ggattcaaat
     9121 ttggaatgat tgatttgtat aaatcggatg ccgttaactt tgttattgaa ggtgatacgt
     9181 tgatcgcacc atttagagct gtcccaagtt tgggaaccaa cgtggcaaaa caaatcgttg
     9241 aagcaagaaa agacggtcca tttttatcca aagaagatct tgccacccgc ggtaaagttt
     9301 caaaaacatt gatcgaatat atgaacgaca atggcgtatt gaaagatcta ccagatgaaa
     9361 atcaattatc gttattcgat atgctataag catctgtttt cctgtctgct tgtaatttta
     9421 agcagagtat ggtatagttc ttataggtaa tgatactaac tgtgagtgag cggatttttc
     9481 gctcactctt tttaatggaa ttacgcactt aattttttaa ggaggcgaaa cttttgagta
     9541 gcgtcgttga aacagtcaca gaaatggtga caccgatttt agatgaacaa aattttgaac
     9601 ttgtcgaagt cgaatttgta aaagaaggaa aaagctggtt cttacgagta tttattgaca
     9661 aagaaggcgg tatcgatatc gaagaatgcg cctttgtcag tgagaaactg agtgaaaaac
     9721 ttgatgcagc agatccagat ccgattcctc aagcttattt cctggaggta tcctccccgg
     9781 gagcagagcg gccattgaaa aaagaaagcg actatgaaaa ggcacttggt gattatgtcc
     9841 atgtctcctt ataccaacca gtagatggcg aaaaacaata tgaaggattt cttcaatcat
     9901 ttgatgctga acagcttaca ttgaaaatac gcataaaaac acgagaaaaa gaattgactt
     9961 ttgaccgaaa aaatattgca aaagctcgct tagctatcca attttaatca cggagaggaa
    10021 tcagaaaaaa tgagtaaaga aatgttaaat gcgttagacg ctttagaagc tgaaaaaggg
    10081 atctcaaaag aaatcgtgat cgatgcttta gaagcagcat tggtttctgc atacaaacgt
    10141 cactatggcc aagcacaaaa cgtcgaagtg gaatttgatc agaaaaaagg aaagatccat
    10201 gtctatgcgg taaaagaagt aacggaagaa gtgatggatt cacagttgga agtctcattg
    10261 aaagatgcac ttttaatcaa tccagcatat gagatcggtg atacgatccg ttttgaagta
    10321 acaccaaaag attttgggcg gatcgctgcg caaacggcta aacaagttat tttacagcgt
    10381 gtacgtgaag cagaaagaac gattatttat aacgaattca gtgcttatga aaaagacatc
    10441 atgcaaggaa tcgtcgaacg ccaggataaa cgttatattt atgtcaatct tggtaaaatt
    10501 gaggcagttc tttctaaaca agatcaaatg ccaaatgaat tttatcaacc acatgatcga
    10561 atcaaagttt atgtttcccg agtagaaaat acgtctaaag gtccgcaagt atttgttagc
    10621 cgcagccatc cagacctatt gcgccgctta tttgagcaag aagtaccaga agtctatgat
    10681 ggaatcgttg aaattgtcag catcgcccgt gaagctggcg atcgttcaaa agtggcagtt
    10741 cgctcaaatg atccaaatat cgatgcagtc ggtacatgtg tcgggccaaa gggacaacga
    10801 gttcaagcaa tcgtcaatga attaaaaggc gaaaacatgg atatcgtcga atggaatgaa
    10861 gatccagctg tattcattgc aaatgcattg aatcctgcac aagtcatgga tgtgatcttc
    10921 gatgagacaa atccaaaggc ctgcacagtt gtcgttccag actaccaatt atcgctagca
    10981 atcggtaaac gcggacaaaa cgcacgttta gctgctaaat tgactaacca taaaatcgat
    11041 atcaaatcag aatctgacat gacggaattt tatgaaaatc aagaacaaca aaaagaaaca
    11101 gaagaactgc atgatgaagc aatcgttcag tcagatttaa cagacgatga atatgaaaca
    11161 attgcattca acaatgaaac ggtcgaagaa aaaccagaag cttaacttta gtaaggaggc
    11221 aaagagatga aacaaaggaa aattccttta cgcaaatccg tggtttcagg tgaaatgaaa
    11281 cctaaaaaag agatggtccg aatcacccgt tcaaaagaag gggaagtatc gatcgatcca
    11341 actggaaaaa tgcctggacg aggagcgtat gtctcacttg agccggaaga agtacaacaa
    11401 gcttgggata aaaaaattct cgatcgagta ctcgaaacaa cattaacaga tgagttttat
    11461 caagaacttc ttgactatgt cactcaccaa aaagcacgta aagagttatt tggaaaatga
    11521 atacagttaa tcggcaaaaa gccatgaatc tcatcggtct agcgatgcgc gcgggaaaac
    11581 taatcacggg tgaagaactg accattgctg aaatccgcaa acaaaaagca aaattggtgt
    11641 ttgtggcaac cgatgcaagc gagaatacaa gaaaaaagat aaaagataag agttcatatt
    11701 atgaagttcc ttgctttgag ctattttctg aagcagaaat cacgcagatg atcggaaaac
    11761 ctcgcaaggt attcggaata atggatgccg gatttgcgaa gaagaccaag gagctaattg
    11821 aaggttagga aggtgattgc atgggcaaca aaagaatcta tgaattagca aaagaactca
    11881 aaaaatctag taaagacgtc gtggaaaaag cacaacaact tggcatcgat gtgaaaaacc
    11941 atatgggtgc gattactagc aatgatgaga agaaattgca acaagcgttc aaaaacccaa
    12001 gcacgaaaca acaagctgca caacaagcaa gcagaaaacc agccaatcaa cagccgaacg
    12061 atcaacgtaa aaaagaaaca acgaacaatc aacaaaaaaa taaaaataac cgcagttatc
    12121 aagatcgcgg tcaagggagc ggtcaagtga atcaaggaaa aaaaccaaca acaaaccaaa
    12181 ataatacggg aaataccagc agccaaaatc gtcaaggaac gagccaaggc ggcaatcaaa
    12241 accgtactaa caataacaac aaaccaaaca ataacaatcg cggcaaattt aataataata
    12301 accgtaatcg ttataataaa aaaggtaaaa aaggcaaaca gcaacaatca actaaaccag
    12361 ctgtaccacc acgcaaattc cgtgaattgc cagatgtatt agagtatact gaaggtatga
    12421 acgtagcaga tattgcgaaa aaaattcatc gtgagccagc agaaatcatt aaaaaattat
    12481 ttatgcttgg tgtcatggtc aatcaaaacc aagcactgga taaagatacg attgaactgt
    12541 tagcgacgga ctatggcatg gaaccacaag aaaaagtcca agttgacatt gctgatatcg
    12601 ataaattctt cgaggcagaa gaagtcgatc cagataaatt agtctcacgt ccgccagtcg
    12661 taacgattat gggacacgta gaccatggga aaacaacttt attggataca ttacgccatt
    12721 cacgtgtaac aagcggcgaa gccggcggaa tcacacagca tatcggtgcc taccagatcg
    12781 atattgatgg taaaccaatc actttcttgg atacaccagg acatgcggcc tttacaagta
    12841 tgcgtgcacg tggagcaagt atcacagata tcacgatctt agttgttgct gcagatgatg
    12901 gcgtcatgcc acaaacagtt gaagcaatca accatgccaa agctgcaggc gttccaatca
    12961 tcgtcgctgt aaataaaatt gataaaccag gtgcaaaccc tcaacatgtt atgcaagaat
    13021 taagtgagta tgagttaatt cctgaagcat ggggtggaga aacgatcttt gttgagatct
    13081 cagcgaaatt cggccaaaac atcgaagaat tgctggaaat gatcctgtta gtcgcagaag
    13141 tagaagattt aaaagcagat ccaacacaac gcgcaatcgg aacagtgatc gaagcacgtc
    13201 ttgataaagg taaaggtcct gtgtcaacct tacttgtcca agaaggaaca cttcatgttg
    13261 gtgacccaat cgttgtcggt aatacttacg gacgtgtccg tgtaatgaca aacgatcttg
    13321 gccgtcgcga taaagaagca ggacctgcaa cgccagtaga aatcactggc ttgaatgatg
    13381 tacctcaagc aggtgaccgt ttcgtagtct tcgaagacga aaagacagca cgtgcagcgg
    13441 gtgaagaacg cgcgaaacgt gcattattag aaaaccgtgc tgccacaagc cgtgtgactt
    13501 tggataactt atttgaaagc ctgaaagaag gcgaattgaa agaagttaac gtaatcatca
    13561 aagcagatgt acaaggttca gcagaagcac tggctgcatc attgaagaag attgatgtgg
    13621 aaggtgtccg tgtaaaaatc gtccattcag ctgtcggagc aatcaatgaa agtgatgtaa
    13681 ccttagcagc agccagcaac gctattatca tcggtttcaa cgttcgtcct acaccgcagg
    13741 caaaagtgca agctgatact gaagaagtcg atattcgtct tcaccgtatc atctataaag
    13801 ccatcgaaga aatcgaaact gcgatgaaag ggatgctaga ccctgaattt gaagaaaaaa
    13861 tcaccggtca aatgatcgtt cgtgaaacct tcaaagtttc taaagttggt acgattgcag
    13921 gtgcctatgt aacagaagga tatattcgta gagatagcgg tgtccgtgta atccgtgacg
    13981 gaatcgtaat ctatgaaggc caacttgcaa gtctgaaacg attcaaagat gacgtgaaag
    14041 aagtcaaaat gggttatgaa tgtggtgcaa tgattgaaaa attcaatgac atcaaagtag
    14101 atgacgtaat tgaaggattt atcatggaag aagtcaaaaa tgactaaaaa ctgataaaag
    14161 gaggccaatc attatggcta actaccgtga ccgccgagtc ggtcaagaaa tcttaaaaga
    14221 agtcaatgat attttgcgca aaaaggtccg tgaccctcgt gtggagaacg taacgatcac
    14281 agatgtgaaa gttacggggg acttacagca agcaacgatc tattacagca ttttatctga
    14341 cttagcatca gataagaaaa cagcacaaga tggattgaat aaagcatcag gattgattcg
    14401 tcgagagtta gggcacaatc taagtattta taagacacct gaattgttct ttgaacttga
    14461 tgaatcagtt gtctatggca accatatcga tgaattgctt cgcgacttga acaaagacta
    14521 atcaaaaact cccgcaaatc ctgtgaaatc aggctctttg tcaataagga ctgatgagtt
    14581 gtgcaaaatc aaatctgagt cagaatgaac cacattctgg ctcag
//
LOCUS       DAFBVQ010000065        14554 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.068, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000065 DAFBVQ010000000
VERSION     DAFBVQ010000065.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14554)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14554)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14554
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.068"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            136..456
                     /locus_tag="LLC22_002267"
     CDS             136..456
                     /locus_tag="LLC22_002267"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435522.1"
                     /translation="MKKRLLWCLLFLSLSLTSQPVFAEETQRSPITGTRLYKNVYVQT
                     TDLDSAIPETEERSLQPRFGYFWYCPTCDYESCWHFLHSTAAAFAFTHTQKYDGHHPV
                     IYEV"
     gene            908..1108
                     /locus_tag="LLC22_002268"
     CDS             908..1108
                     /locus_tag="LLC22_002268"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5435523.1"
                     /translation="METGTVKWFNSEKGFGFITAENGNDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEEGQRGPQATNVTKA"
     gene            1255..4044
                     /locus_tag="LLC22_002269"
     CDS             1255..4044
                     /locus_tag="LLC22_002269"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628443.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DEAD/DEAH box helicase family protein"
                     /protein_id="HBK5435524.1"
                     /translation="MKPRTYAVVDIETTGTNPKEDRIIQFGCVMIESGRITSRFSIDI
                     HPGRKISKQIQHLTGITNQRVQKAPYFEDVAQTIYNLLADTIFVAHNIYFDYNFLNHE
                     LMRCGLPSLKIPGIDTVELAQIFLPTEPSFRLADLSESLGFIHENPHQADSDAEVTGQ
                     LLLLIEERMRKLPIITLEQIARLSRHTGMDTSRFIYHVIEEMKEKPEPLDPSLEIVDG
                     LALQKKEVELFTSVHYGERTYPRKKQAKEKMFGKTLMYRKEQNRLMNAVYDHFTKDES
                     KDLMIEAATGMGKTIGYLLPLSYLATPEKPAVISTVSLVLQQQIIEKDIPLLNQLLDQ
                     PIQPVIIKSYRHYIDLQRFKGTLVEPPEQKQYALYQMAVLVWLTQTKTGDLDELHLTN
                     LNHSFFADIAHRGIGFLARNQSFYEQDFVRFLQKKIRQSNFLIVNHAFLIQETQRKEP
                     LLPASPFLLIDEVHHLPEIAEKVNDKRLSINYFHKQIQQLEEPNQLFDRIQSYLPKEH
                     EALRWLSIYREELSALCEAQICMAEGLMSLVSGKQPNGQYPEEVMMTKEMLDQLPLES
                     GTAIDHLQLFYQEIQQLQSQMRLTFEIIQESWTNQMRIDLASLYSLFDQLDKQYLLMD
                     QWLEDWRDHLIHWFVPGNTAQQMIFHLHDFQAAMLPSTVWYPRYDRILYIGGTLKIGP
                     NRHYLSKRLGIEAAPLKVIASPYDYEKQARIYVPKEAPAVHQVSNQAYIDYLETALTG
                     LIEQEDRPILVLFTSHDVLQKVYQKMHLSMLEKGREILAQGFGGSREKLLKRFILSEK
                     SVLFGADSFWEGVDLPGDALQIVVVTRLPFDNPLRPMVKARNAYLESEGINPFYQESV
                     PKAALKLRQALGRLIRTETDRGVLLILDRRLVTAKYGARIIHALPKKVPIKELAMEEI
                     YQDIHEFLKKNEEGS"
     gene            4091..4618
                     /locus_tag="LLC22_002270"
     CDS             4091..4618
                     /locus_tag="LLC22_002270"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316397.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5590 domain-containing protein"
                     /protein_id="HBK5435525.1"
                     /translation="MKIKERRPLKKKQTKEKTINRVLLGLIVFLLAVIVISSIFYLRS
                     SRPAVQAKKEAVEIAKKYANLEEADHFYWFTRKKTYFSLTGTNDKGKEIAVIIPKSGE
                     KVKVLDQTKGLTENEAKQTIAAAHPEIQIEKAALGMYDDQPVWEVVGKETNGKLNYYL
                     IGFESGDEVKTIKGI"
     gene            4639..5829
                     /locus_tag="LLC22_002271"
     CDS             4639..5829
                     /locus_tag="LLC22_002271"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5435526.1"
                     /translation="MELSKRTKRLEPSVTLAAAAKAKALKAKGRDVLSLTVGEPDFAT
                     PENIQEAAIEAIRNGKASYYTPTAGIPELRQAIVDYLKKNYGLVYEPSQTVVTDGAKF
                     ALYTLFQTILDPQDEVIIPVPYWVSYGEQVKLAEGLPVFVKGEESNSWKVTVEQLEQA
                     RSEKTKAVIINSPSNPTGMIYSKNELQAIGEWAVKNDILIVADDIYGRLVYNGNEFTP
                     IATISEAIKNQTIIINGVSKTYAMTGWRIGYAVGNPVIINGMIAVASQSTSNPTAVSQ
                     YAAVEALKGEQDTVEEMRNAFEERLNTLYSLVAELPGVSLEKPQGAFYLFPNVKETLR
                     MCKYENVTQWVEDLLEETGVALVTGEGFGAPENVRMSYATDRATLEEAVRRIKQFIES
                     KSQN"
     gene            5869..7167
                     /gene="asnS"
                     /locus_tag="LLC22_002272"
     CDS             5869..7167
                     /gene="asnS"
                     /locus_tag="LLC22_002272"
                     /EC_number="6.1.1.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016180901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="asparagine--tRNA ligase"
                     /protein_id="HBK5435527.1"
                     /translation="MEQIQIIDSKNHVGETVTIGAWVANKRSSGKIAFLQLRDGTAFF
                     QGVVVKSEVSEEVFQTAKNLHQETSVLVTGEIREDSRSKFGYEIGITNVEVVSESHDY
                     PITPKEHGTDFLMDHRHLWLRSSRQHAIMQIRNEIIRATYEFFNQHHFVKIDPPILTG
                     SAPEGTTDLFETNYFDQKAYLSQSGQLYMEAAAMAFGKVFSFGPTFRAEKSKTRRHLI
                     EFWMIEPEMAFTHQEESLEVQEQYVAFLVQNVLDHCEYALDVLGRDKEVLKTYTKLPF
                     PRITYDDAIELLKKNGFDDIEWGEDFGSPHETFIANSFEQPVFILNYPKAIKPFYMKP
                     HPTREDVVICADMIAPEGYGEIIGGSERATDYDFLLEQIRNHGLDEKEYSWYLDLRKY
                     GSVPHSGFGLGLERTVTWIAGIDHVREAIPFPRLLNRIYP"
     gene            8220..8894
                     /locus_tag="LLC22_002273"
     CDS             8220..8894
                     /locus_tag="LLC22_002273"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288769.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SGNH/GDSL hydrolase family protein"
                     /protein_id="HBK5435528.1"
                     /translation="MKKRILFIGDSITDAGRDRAEATDLGKGYPLLIAGKLISQYPTM
                     EFECMNRGIGGDKIADLQVRWQEDCLALQPDYVSILIGINDTWHNTSDQAIFGTEKSA
                     QQFESVYRKLLNELQTVGICNIILMEPFVLPITDDRHGWRKDLDPKIQIVRKLAKEYG
                     ALLVPLDGIFNALGIVYGFSKYTREDGVHPTIGGHEIIAQSWIDAIAAVDFFSGDKNE
                     RKKSEK"
     gene            8891..9232
                     /locus_tag="LLC22_002274"
     CDS             8891..9232
                     /locus_tag="LLC22_002274"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435529.1"
                     /translation="MMEIRWAVKEDLPQINQLITDHPESFVKAKTAADLNDKNKLLLV
                     AVTKEKRIIGFAQADVQQSEERLDQRPSGKLIQHTLVTKENTEEIQKKFAEYLILEAK
                     KRRIKSFFAQF"
     gene            9262..9621
                     /locus_tag="LLC22_002275"
     CDS             9262..9621
                     /locus_tag="LLC22_002275"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YccF domain-containing protein"
                     /protein_id="HBK5435530.1"
                     /translation="MSCLGNVIWFIFGGLIGGLSWLAAGILWCITIIGIPIGMQCFKI
                     ASLSFAPFGKEVIYHQSGMSLIVNIIWLIVSGLPIALAHVVSGILLCITIIGIPFAKQ
                     SFKLARLALMPFGAEIV"
     gene            10145..12226
                     /gene="cadA"
                     /locus_tag="LLC22_002276"
     CDS             10145..12226
                     /gene="cadA"
                     /locus_tag="LLC22_002276"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBK5435531.1"
                     /translation="MKSYRLEGLDCANCAMKIEKGVQKINGVKEATVNFTSGKLTIDA
                     EEDHLATIEQEIKKVVKELEPDVKVTEIDKEKVSEHGNEKERNTLFRILFSLAGIALL
                     LLFDFNEPIRLIGYLLIYLLIGYDVVKKAVMNIVKGKIFDENFLMSVATIGAMLIGEY
                     PEAVAVMLFYQIGEYFQGLAVSHSRKSIRELMAIRPETAHVQTTEGLMTVNPEDVQIG
                     QFVLVKPGERVPLDGTIIEGESLVDTSALTGESVPKSVYVGETVLSGFINKNKPFLVQ
                     VEKSYENSTISKLLELVENASSKKAPAENFITKFARYYTPVVVGLAVLLAVLPPLVVS
                     GAAFSEWIYRALTFLVISCPCALVISVPLSFFGGIGGASKIGVLVKGSNYLELLAQTE
                     TVVFDKTGTLTKGDFSIQTIDTKIDPKIFMQYVASAEQFSTHPIAQSVLEGYAGPLLP
                     TANIQEFAGEGILAEVDGKQVLAGNHKLMERFEISFPSSQEIGTLLYLAIDQSYSGYL
                     VIADTLKEDAVDALVQLKKAGVKNTVMLTGDSKKIADHIGKQVGVDKIYSELLPEDKV
                     QRLEEILQRNNKKTAFVGDGINDAPVLARADVGIAMGGLGSDAAIEAADVVIMNDQPS
                     KIAEAIHLAKKTLKIVKQNIVFAIGIKILVLALGAFGFASMGDAVFADVGVTVLAVLN
                     AMRSLHVKNKR"
     gene            12537..14003
                     /locus_tag="LLC22_002277"
     CDS             12537..14003
                     /locus_tag="LLC22_002277"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5435532.1"
                     /translation="MNNKQLRWFTVALIAFNMVWGMGNVVNNYAQQGVSVVTSWLLIL
                     AIYFIPYALIVGQLGSAFKDSKGGVSSWVENTTSNKRLAYYAAWTYWVVHIPYLAQKP
                     QAILIAGGWAVQGNGNIVNTMSVQMVAVISLIIFLAFLYLSTKGLSTLKVIGGLAGTA
                     MFVMSILFILLAVTAPFINPTMEFATPHMNQVKTYIPTFDFSYFTTVSMLVFAVGGAE
                     KISPYVNSTRNPAKEFPKGMIFLAAMVGICAVLGSVAMGMLFASDNIPKDLMANGAYS
                     AFQILGNYYGIGNSLMIIYALTNMIGQISALAFSIDAPLKILLADADPEFVPNWLRKR
                     NRKGTLVNGYLLTGILVGIIILLPIFGIKDMNELVKWLTNLNSVVMPMRYLWVFLAYM
                     MLNKAYKKFNSEYKFVKNPKIGFIFGAWCFAFTAFACILGMVPKVDYTADPKAWWFQL
                     FTNIITPIVLILLGMILPAIARRDKNKEITEPETVVQP"
BASE COUNT         4807 a         2526 c         3117 g         4104 t
ORIGIN      
        1 agaggttgtg acgtggtcac gacctctttt tgacgattat gatacaaaaa acatcattta
       61 tgaacaaaat gtgaataacg ggcgttcttg agatatgatt ttaattggga aaaacttatc
      121 gataaggagg tctttatgaa aaaaagactg ttatggtgtt tgctgtttct atccctaagt
      181 ttaacaagtc agccagtttt tgctgaagaa acacagcggt ctcctattac aggcacacgt
      241 ctgtacaaaa atgtttatgt acagacaaca gatcttgatt ctgcgattcc tgaaacagaa
      301 gaacggtctt tgcagccaag atttggttac ttttggtact gtccgacctg tgattatgaa
      361 agttgctggc atttcttaca ttctacagct gcagcttttg cttttactca tactcagaaa
      421 tatgatggac atcatcctgt tatttatgag gtatagatat gagcaaaaaa gaaaaactaa
      481 tctcgttgat cgtattggtt tgccttgttc ttctggtaac tgtcataggc tatcagaaat
      541 accatgagaa catcagacct actaaagaat cttccccagc ctcgaccgtt gaaacagaac
      601 cgataagtag tcagaaagaa taattttttt agtttaaaga agaacatcag agcaaaaaaa
      661 caccaactga acaatatgtc gtttatttta aaaaaagttc ggtttttcac tttatgtaat
      721 cgctgagaaa acttttttta ataaaaaaag tcgaaaaact ctagcttttt tgtaaacggt
      781 atgatatact ataggagtag tttttgttcg gtaatctgtg gtagcttgtt tcaaataaac
      841 atcttccaga tatacaccat tcaagtaatt gcaaaatatg tgttgataca caaggaggat
      901 ttttattatg gaaacaggta cagtaaaatg gtttaactca gaaaaaggat ttggattcat
      961 cactgcagaa aacggaaacg atgtattcgt tcatttctca gctatccaag gcgacggatt
     1021 caaaacttta gaagaaggcc aagcagtaac tttcgatgtt gaagaaggcc aacgcggacc
     1081 tcaagcaaca aacgttacta aagcttaatt aacctatact aaaaaataaa cgcccagaca
     1141 tttgcgtgtc tgggcgtttt tgtctatttt ctttaaaaag cgatgagagt atttttctgc
     1201 actttgtagt ataatttcaa aagaacatta gaggcaggag aagaggaaga tattttgaaa
     1261 ccaagaactt atgcagtcgt tgatatcgaa acgactggga cgaatccaaa agaagatcgg
     1321 atcatccaat ttggctgcgt catgattgaa tcaggtcgga tcacttcacg tttttcgatc
     1381 gatattcatc cagggcggaa gatttcaaaa caaatccagc atttaacagg gatcacgaat
     1441 caacgcgtcc aaaaagcgcc ttatttcgaa gatgtcgccc aaacgattta caatcttttg
     1501 gcagacacca tatttgtcgc gcataatatt tattttgatt ataatttttt gaaccatgaa
     1561 ctcatgcgat gcggacttcc tagtttgaag ataccaggca tcgatacagt agaacttgca
     1621 caaattttct tgccgacgga accaagcttt cgcttagctg atttgtcaga aagccttgga
     1681 tttattcatg agaatcctca tcaggcagat agtgatgccg aagtgacggg tcaacttctt
     1741 ttgctgatcg aagaacggat gagaaaattg ccaatcatca cgttagagca gattgcgcga
     1801 ttaagtagac acacaggtat ggatacgagt cgtttcattt atcatgtgat tgaagaaatg
     1861 aaagaaaaac cagagccact tgatccctca ttagaaatcg tcgatgggct agctttgcag
     1921 aaaaaagaag tggaactatt cacatccgtc cattatggcg agcggacata tccaagaaaa
     1981 aaacaagcaa aagaaaaaat gtttggtaaa acactgatgt atcgaaaaga acagaacaga
     2041 ctgatgaatg cggtctacga ccatttcaca aaagatgaat caaaagattt gatgatcgaa
     2101 gcagctacag gaatgggtaa aacaatcggt tatctgctgc cattgagtta tttggctaca
     2161 cctgaaaaac ccgctgtcat cagtaccgtt tcgctagttt tgcagcagca gatcatagaa
     2221 aaagacattc cattgctgaa tcaattgcta gatcagccca tacaacctgt aattatcaaa
     2281 agctatcgcc actatattga tttacagcgt tttaaaggca cacttgtgga accgccagaa
     2341 caaaaacaat atgctttgta tcaaatggcg gtcttagttt ggctgacgca aacgaagacc
     2401 ggtgatttgg atgaattaca tttaacaaat ttgaaccatt cattctttgc agatatcgcg
     2461 cacagaggta ttggattttt agcaagaaat cagtcatttt acgaacaaga ctttgttcgt
     2521 ttcttgcaaa agaaaatcag gcaaagtaat tttttgattg tcaatcatgc gtttttaata
     2581 caagaaacac agcgaaaaga accattgctt ccagctagtc catttttgtt gatcgatgaa
     2641 gtacatcatt tgccggaaat cgctgaaaaa gtaaatgaca aacgattaag tattaactat
     2701 ttccataaac aaatccagca attagaagaa ccaaatcagc tgtttgaccg aatacaaagc
     2761 tatttaccga aagaacatga agccttacgc tggttatcga tttatcgaga agaactttct
     2821 gcgctatgcg aagcacagat ttgtatggca gaaggattaa tgagtttagt gagcggcaag
     2881 caacctaacg gacagtatcc agaagaagtc atgatgacaa aagagatgtt ggatcagctg
     2941 ccactggaat ctgggacagc cattgatcac ctgcagcttt tttatcagga gatccagcag
     3001 ctacagtcac aaatgcgtct gacttttgag attatccaag aaagctggac aaaccagatg
     3061 cggatcgatt tagcaagttt atatagctta tttgatcaat tagacaagca gtacttgctg
     3121 atggatcaat ggctggaaga ctggcgagat catttgatcc attggttcgt tcctgggaac
     3181 acagcgcagc agatgatttt tcatctccat gattttcaag cggctatgtt gccgtcgact
     3241 gtttggtatc ctcgatatga tcgtattctt tatattggag gaacgctgaa gatcggccct
     3301 aatcgacact atctctctaa gcggcttggc attgaagcag cacctcttaa agtgattgcc
     3361 tctccttatg attatgagaa acaggcaagg atctatgtgc caaaagaggc acctgccgtc
     3421 catcaagtca gcaatcaagc atatatcgat tatttagaga cagcacttac aggtctgatc
     3481 gaacaagaag atcggccaat acttgtgtta ttcacttctc atgatgtttt gcagaaggtc
     3541 tatcagaaaa tgcatctgtc tatgctagaa aaaggacgag aaatactagc tcaagggttt
     3601 ggcggaagcc gggagaagct tttgaaacgc ttcattttgt cagaaaaaag cgtattgttt
     3661 ggcgctgaca gcttttggga aggtgtagat ttgcctgggg atgctttgca gatcgttgta
     3721 gtcacacgtt tacccttcga taatccgctt cgcccgatgg tcaaagctag gaacgcttat
     3781 ttagaatcag aggggatcaa tcctttttac caggaatccg tacctaaagc agctttgaag
     3841 ttacgccaag cattaggtcg cttgataagg acggagacag atcgtggcgt attgcttatt
     3901 ttggatcgaa gactagtcac tgcaaaatat ggtgcacgga tcatccatgc attaccgaaa
     3961 aaagtaccga tcaaagagct agctatggag gaaatctatc aggacatcca tgaattctta
     4021 aagaaaaatg aagaaggaag ttagaggagc tgtctttttt cataattaaa atctgctata
     4081 atgaaaagga atgaagataa aggagcgacg acccttgaag aaaaaacaga caaaggaaaa
     4141 aacgattaat cgcgtgttac ttggcttgat cgtattttta ttagcggtca tcgtgatcag
     4201 ctcgattttt tacttgcgtt ccagtcgtcc ggcggtgcag gcgaagaaag aagcagtaga
     4261 aatcgcaaag aaatatgcaa atcttgagga agccgatcat ttttattggt ttactcgaaa
     4321 gaagacatac ttttcactga caggtacaaa tgataaagga aaagaaatcg ccgttatcat
     4381 tcctaaatct ggtgaaaaag taaaagtatt ggatcaaaca aagggactga ctgaaaacga
     4441 agcaaaacag acaattgctg cggcccatcc tgaaatccaa atcgaaaaag ctgctttagg
     4501 gatgtatgat gatcagcctg tgtgggaagt agtaggaaaa gaaacaaatg ggaaactgaa
     4561 ttattacctg attggctttg aatctggaga tgaagtcaag acaatcaagg gaatttaaaa
     4621 ggtaaaggaa tgaatgggat ggagttatca aaaagaacaa aacgattaga accgtctgtc
     4681 actttggcag ctgcggcaaa ggccaaggca ttaaaagcaa aaggcagaga tgtgctgagt
     4741 ttgactgtgg gagaaccgga ttttgcgaca ccagaaaaca tccaagaagc agcaatcgaa
     4801 gcaatccgca acgggaaagc tagctattat acaccaacag caggaatccc agagcttcga
     4861 caggcaatcg ttgattatct gaagaaaaac tatggacttg tctatgaacc ttcacaaaca
     4921 gtcgtaacag acggagcgaa atttgctttg tatacccttt tccaaacgat ccttgacccg
     4981 caagatgaag tcatcattcc tgtgccttac tgggtcagtt acggtgagca agtaaaactg
     5041 gcagaaggac ttcctgtctt tgtgaaaggg gaagaatcca atagctggaa agttactgtt
     5101 gaacagctag aacaagcacg ttcagaaaaa acaaaagccg taatcatcaa ttctccatcg
     5161 aatccgactg gaatgattta tagcaagaat gaactgcagg caatcggtga atgggcagta
     5221 aaaaatgata ttttgatagt tgctgatgat atttatggtc gtttagttta taatggcaat
     5281 gagtttactc caattgcaac gatttcagaa gcaatcaaaa atcagactat catcatcaac
     5341 ggcgtgtcta aaacatatgc gatgacaggc tggcgcattg gttatgcggt gggaaatcct
     5401 gtgatcatca atggaatgat cgctgttgct tcccagtcaa ccagtaatcc gacagcagtc
     5461 agtcaatatg cagctgttga agcattgaaa ggcgagcaag atacagtgga agaaatgcgg
     5521 aacgcctttg aagaacgcct gaatacgtta tattcgcttg tggcagaact gccgggtgtt
     5581 tctcttgaaa agccacaagg agctttttat ctttttccta atgtaaaaga aacgctacgc
     5641 atgtgtaaat atgaaaatgt cacacaatgg gtagaagatc ttttagaaga aacaggggta
     5701 gcgcttgtga ctggcgaagg ctttggggca ccagaaaatg tccgcatgag ttatgctact
     5761 gatcgcgcta cgttagaaga agcggtacgc agaatcaagc aatttattga gagtaaaagt
     5821 caaaattaat cctaaagaaa ttcaaggaat ataaaaggag agtcatacgt ggaacaaatt
     5881 caaatcatcg attcgaaaaa ccatgtggga gaaacagtaa caatcggcgc ttgggtcgca
     5941 aataagcgat caagcggaaa aatcgcattt ttacaattaa gagacggaac agcctttttc
     6001 caaggtgtag ttgtaaaaag cgaagtgtcg gaagaagttt tccaaacagc taaaaatcta
     6061 caccaagaaa catccgtgtt agtaactgga gaaatccgtg aagacagtcg ttcaaaattt
     6121 ggttatgaaa tcggaattac aaatgtggaa gtggtaagcg agagccacga ttatccgatc
     6181 acaccaaaag aacacggaac agacttcttg atggatcatc gtcatttatg gctgcgttct
     6241 tcaagacaac atgcgattat gcagatcaga aatgaaatca ttcgtgcaac gtatgaattc
     6301 tttaatcaac atcattttgt caaaattgat ccgccgatct tgactggttc tgcaccagaa
     6361 ggcactacgg atctattcga aacaaattac tttgatcaaa aagcttattt atctcaaagt
     6421 ggccaattat acatggaagc tgctgctatg gctttcggaa aagtcttttc attcggtccg
     6481 actttccgtg ctgaaaaatc aaaaacacga cgtcatttga tcgaattctg gatgatcgaa
     6541 ccagaaatgg ctttcactca tcaagaagaa agtttagaag tacaggaaca atatgtagca
     6601 ttcttagtac aaaatgtttt agatcattgc gaatatgcat tagatgtact aggacgagac
     6661 aaagaagtct taaaaactta tacaaaattg ccattccctc gtattactta tgatgatgcg
     6721 atcgaattac tgaagaaaaa tggatttgat gacatcgaat ggggcgaaga ctttggttca
     6781 cctcatgaaa cgttcattgc gaattcattc gaacagcctg tctttatcct aaactatcca
     6841 aaagccatca agccattcta catgaaacca catccaacaa gagaagacgt ggtgatctgt
     6901 gcagatatga tcgcaccaga aggttacggt gaaattattg gcggaagcga acgggcaaca
     6961 gactatgatt tcttgctaga acaaatccgt aatcacggtt tggatgaaaa agaatattca
     7021 tggtatcttg atctacgtaa atacggttct gttccgcact ctggttttgg tctaggtctt
     7081 gaacgaacag tcacttggat tgctggtatc gaccatgtac gtgaagctat tccattccca
     7141 cgtttgttga accgaattta tccataagag gtgatgaaaa agctgttctg catcaagtaa
     7201 ttagaacagc caagcaaaaa cagctgttca tgtttttgaa ttggcgggac ttattaccgc
     7261 agatgtaagc ttttgaatac cgtttagtgg agaggttgtg aaaaagctgt ttagtttcga
     7321 gtattaagaa aaattttgtg gaaatggctt tccacatttt tgcataaatt tggcttaata
     7381 ccgagaaact ggcttttgaa caccgtttaa ggaagaggtt gtgcgcctgc cgttcagctc
     7441 cgagtcacaa ggagtaattt caaaaaacag tttttcatgt ttgatgacta ttgtgacttg
     7501 tgaccgagga gttggccgga gagcaccgtt tattctaaaa aagaactgcg aactctcgca
     7561 gttctttttt taaaatacgg gataaaggaa gtttccagca gacaagagaa gaaagcaaaa
     7621 gaaattgcta tttgattcac aaggttctat aacgaaatcg caatcaatca aacatttaca
     7681 aagaaggtaa ttcaaatgga aatctgattt gatgatgctt ctgctgttga aataaagcag
     7741 catctagcac ctgaaaacaa actaatagta acattcgaag atggagtagg tccgtatttt
     7801 cagcatgcaa taatccatat gtaagttcaa ttcacccttg aaatcatcgg accagataaa
     7861 gttatgacca atctatccca agcaatctag aagagatatt agtaaaggga catttactag
     7921 aagtcttaga tgagcctata aatatatgtt ctgatggcgt catcagtggt ctgattgacg
     7981 gaagcttagg tgtgatcgat ctctctggac caaacaacga aggaatcaag gggaatccgg
     8041 cacgttaaga aaaaaatagc ataaaaaact agacacttga tgagcgttca ttcaattgtt
     8101 tgaagggact aggctggtgt cattttttat acatatattt tctctttcgt cttgataggg
     8161 cttatgggat aatataagga agaaaatcat cgttttattc aaaaaggagt ttttgacaaa
     8221 tgaaaaaacg tatattattt atcggtgata gcattacaga cgcaggaaga gaccgagcag
     8281 aagcaactga tctaggtaaa ggttatccac ttttgattgc cggaaaacta atctcccaat
     8341 atccaacgat ggaatttgaa tgcatgaacc gtgggatagg aggagacaaa attgcagatc
     8401 tgcaagtacg ctggcaagaa gattgtttag ctttacaacc tgactatgta tcgattttga
     8461 tcggaatcaa tgatacctgg cataatacta gcgatcaggc tatattcgga actgagaaat
     8521 ctgctcagca atttgaatcc gtttatcgaa aattactaaa tgaacttcaa acagtgggaa
     8581 tctgcaacat catcttgatg gagccgtttg tacttcctat aaccgacgac cgtcatggct
     8641 ggcgtaaaga cttagaccct aaaatccaaa ttgttcgtaa acttgctaag gaatatggcg
     8701 cattgctggt tcctttagat ggtatattca atgctttagg gattgtttat ggtttttcga
     8761 aatatacaag agaagatggg gtccacccaa cgattggcgg acatgagatc attgcacaaa
     8821 gctggataga tgcaattgcc gcagtcgatt tttttagtgg agataaaaat gagcgaaaga
     8881 aaagtgagaa atgatggaaa tacggtgggc agtaaaagaa gatctacctc aaatcaatca
     8941 gctgattact gatcatccag aatcattcgt aaaagcaaaa acggcagctg acctaaatga
     9001 taagaataaa ctattgctcg ttgctgtaac aaaagaaaaa cggattatcg gatttgcgca
     9061 agcggacgtg caacagtcag aagaacgatt ggatcagcga ccatcaggaa aactaatcca
     9121 acacacatta gtaacaaaag aaaatacgga agaaatccaa aaaaaatttg cagaatattt
     9181 gatactggaa gctaaaaaaa gaagaataaa atcatttttt gcccagtttt aatcaaaaac
     9241 agtaatagaa ggagaaatac aatgagttgt ttaggaaatg tcatctggtt tatattcggc
     9301 ggactaatcg gtggtcttag ctggttagca gcggggatac tttggtgtat cacgatcata
     9361 ggtatcccaa tcggtatgca atgttttaag atcgcctccc tttcttttgc gccttttggc
     9421 aaagaagtaa tttatcacca gtctggcatg tcattgattg ttaatatcat ctggctgatc
     9481 gtttcaggcc taccaattgc tctcgcacat gtcgtcagcg gcatccttct atgtatcacg
     9541 atcataggga taccttttgc caagcaatct ttcaaacttg ctcgattggc gttgatgcca
     9601 ttcggtgcag aaattgtata aaagagaata ataaaggtta gataaagcat agagtcaggt
     9661 gggatacatg tatttcacct gactctatgc gttctcctgt ataagttctt ccatgtgact
     9721 tttacgtctt ttatttatat ggggttactg tttatggaaa gttgaaataa ttttcattaa
     9781 agaactcttt ctatattttt gaaagcgtag tggagcttcg aatatctggg aaggacattt
     9841 tgcagggatt gaaaaaagat attgtcctat cgaaaaatta atgaatttag acaaattgcc
     9901 agcaacaggc ttcaaactta gttgctatcc tgtcaagatc aagaaggcaa gtgcgggttg
     9961 gataagagca gtggcaatga tcgaaaagaa aaagaaagaa taagccaaaa catctgtatg
    10021 gaagaaattt tccgatgcag atgtttttca ttttttcttt cggatacctt gacatatgaa
    10081 taaccgttca tttataatta gttatgaaga gatattcata tgttgaggcg aggaggtcat
    10141 taaaatgaaa agttacagat tagaaggttt agattgtgcg aactgtgcaa tgaaaatcga
    10201 aaaaggagtt cagaagatca atggagtcaa ggaagcaacg gtaaacttca cttctggaaa
    10261 actaacgatt gacgcagagg aagatcattt ggctacgatt gaacaagaaa taaaaaaagt
    10321 agtgaaggaa ttagaaccag atgtcaaagt aacagaaata gataaggaaa aagtatctga
    10381 acatggaaat gaaaaagaga gaaatacgct gttccggatt ttattttccc ttgcaggtat
    10441 cgctttattg ctattatttg attttaatga accaattcgc ttgatagggt atttattgat
    10501 ttatctgctg ataggatatg atgtagtgaa gaaggcagtg atgaatatcg tcaaaggaaa
    10561 aatctttgat gagaattttc ttatgtctgt tgctacgatt ggcgctatgt tgatcggtga
    10621 atatccagaa gccgtagcag tgatgctatt ttatcaaatc ggcgagtatt tccaaggatt
    10681 ggcagtcagt cattcaagaa aatcgattcg cgaattgatg gcgatccgtc cagaaacagc
    10741 tcacgtgcag acgacggaag gattgatgac cgtgaaccct gaagacgtgc agatcggtca
    10801 gtttgtactt gtgaagcctg gtgaacgtgt accgttagat ggaacgatca tcgaaggaga
    10861 atcattagtc gatacgtcag cacttacagg agaatcagtc cctaaatctg tatatgttgg
    10921 tgaaacagta ttaagtggat ttatcaataa aaataaacca tttttagttc aagtagaaaa
    10981 atcttatgaa aattctacta tcagcaaatt attagaatta gtagaaaatg ccagcagtaa
    11041 aaaagcacca gctgaaaatt tcattactaa attcgcgcgc tattacacac cagtcgttgt
    11101 aggattggcc gttttattag ctgttttacc tccacttgtt gtttctggag cggcgttttc
    11161 tgaatggatc tatcgagcat tgacattttt agtgatctca tgtccatgtg cattagtgat
    11221 ctccgtaccc cttagtttct ttggcggtat cggaggagca agtaaaatcg gtgtattagt
    11281 aaaaggttca aattacttgg agttgcttgc acaaactgag acagtggtat tcgataaaac
    11341 cggcacatta acgaaaggtg acttttcgat ccagacgatc gatacaaaaa tcgatccaaa
    11401 gatattcatg caatatgttg cgagtgcaga acagttttct acacatccga ttgctcaatc
    11461 tgttttagaa ggctacgcag gtccgctttt accaacagct aatatccaag aatttgcagg
    11521 tgaagggatc ttagctgaag ttgatggcaa acaagtatta gcaggtaatc acaaattgat
    11581 ggaaagattt gaaatctctt ttccttcaag tcaagaaatc ggtacattgc tttatctagc
    11641 gatcgatcaa agttacagtg gttatcttgt tattgcagat accttgaaag aagatgccgt
    11701 agacgcattg gttcaattaa aaaaggctgg tgtgaagaac acagtcatgt tgacgggcga
    11761 ttcgaaaaaa attgctgatc atatcgggaa gcaagtaggc gtggacaaga tatatagcga
    11821 attgcttcca gaagataaag tgcagcggtt agaggaaatc ttacaaagaa acaataaaaa
    11881 gaccgcattt gtcggagatg gaatcaacga tgcaccggtg ctagcaagag cagatgtagg
    11941 aatcgcaatg ggtggattgg gaagcgatgc tgcaattgaa gcagcagatg tagtcatcat
    12001 gaatgatcaa ccatcgaaga ttgcagaagc aatccattta gcaaagaaaa cattgaaaat
    12061 cgtcaaacag aacattgtct ttgctattgg gataaaaatt ttggtacttg ccttaggtgc
    12121 ttttggtttt gcatcaatgg gagatgcagt atttgcagat gttggggtga cagtattagc
    12181 tgttttgaat gccatgcgaa gcttgcatgt aaaaaataaa cgttgatcaa tgaagaggac
    12241 gaatgaacgt cctctttttt ttatatcctt ttcttaatga aaaatgtaaa gaaaatagat
    12301 aggattataa aataactaat gtttttaatt ttgcagaaaa ttcaaaatag cttgaaattc
    12361 aataaggtaa atgaaataaa agaaaataac ttattttttt gatggaaaaa atatgaaaaa
    12421 acgatgtgta ttaaataaaa gaatacacac ataaaataac actgtcttgt aagtttgtta
    12481 aaaattgaat atgattacat ctggataaca aatttttatc ataaaggaga gaacgaatga
    12541 acaacaaaca attacgctgg tttactgttg cgttaattgc atttaacatg gtttggggca
    12601 tggggaatgt agttaataac tatgctcagc aaggagtatc agttgtcacc tcttggctat
    12661 tgattttggc catttatttt attccatacg cattgatcgt tggacaatta gggtcagcct
    12721 tcaaggatag taaaggaggc gtcagttcat gggtcgaaaa tacgacatct aataaacgac
    12781 tggcatacta tgccgcttgg acttactggg tcgtccatat tccttatttg gcacaaaagc
    12841 ctcaagcaat cctgattgct ggcggttggg cagtccaagg aaatggaaat atcgtaaata
    12901 cgatgtcagt acaaatggta gcagttattt cacttattat atttcttgcc tttttatatt
    12961 tatcaacaaa aggactttct actttgaaag tgattggcgg actggccgga acagcgatgt
    13021 tcgtcatgtc gatcttattt attcttttag ctgtaacggc accgttcatc aatccaacga
    13081 tggaatttgc cacaccacat atgaatcaag tgaaaacata tattccaaca tttgatttca
    13141 gttatttcac aaccgtttcg atgctagtat ttgcagttgg aggagcggaa aaaatatccc
    13201 cttatgtcaa ctctacaaga aatcctgcaa aggaatttcc taaagggatg atcttcttag
    13261 cagcaatggt agggatttgt gctgtattag gctcagtcgc aatgggtatg ctgtttgcta
    13321 gcgataatat tcctaaagac ttgatggcaa atggggcata cagtgctttt caaattttag
    13381 gtaattacta tggtatcggt aactcattga tgatcattta cgcattgaca aacatgattg
    13441 gacaaatctc cgcattagcc ttttcaattg atgcaccact aaaaatcttg ttagcagatg
    13501 cggatccaga atttgtacca aactggctac gtaaacgtaa tcgtaaaggt acattggtga
    13561 atggttatct tctgacaggt atactagtag gaatcattat tttgttgccg atctttggta
    13621 tcaaagatat gaatgaatta gtaaaatggt tgacgaactt gaactcagtt gtcatgccaa
    13681 tgcgttacct atgggtgttc ttggcatata tgatgttgaa taaagcttat aagaaattca
    13741 attctgaata taaatttgtt aaaaatccaa aaatcggttt tatctttggt gcttggtgct
    13801 ttgccttcac tgcgtttgca tgtatcctag gaatggtgcc aaaagtagat tatactgctg
    13861 atcctaaagc atggtggttc caattattca cgaatatcat cacaccaatt gtcttgatct
    13921 tattaggtat gatcttgcca gcaattgctc gtcgagacaa aaacaaagaa atcactgaac
    13981 cagaaacagt ggttcagcct taaaatagaa atacttgtta caagaggttg tgacagaagt
    14041 ggtcagcttc aagaaataag aaggaattta cgaaaattgc ttctcaaatt tttgtgaagt
    14101 ttcggcttgt ttttcgcaga agctacttct ggaacaccgt gaatcagagg ttgtgaaaaa
    14161 gctgtcctgc atcaagtaat aagaacagcc aaacaaaaat agcccctcat atttttcgtt
    14221 ttgctgggct tattaccgca gatgcaagct tttgaacacc gtttaagaaa gaggtagtga
    14281 gcctgccgtt taactccgag tcacaaggag caatttcaaa aaacaacttc tcatgtttgt
    14341 tgactattgt gccttgtgac cgaggtgttg gcaggagaac accgtttaag gaagaggttg
    14401 taaaatcagc gatttgacct gagtattaga ggaacaaacg aaaaaatagc tcctcatatt
    14461 ttgccgtttt ttgagttaat gctgaaggtc agctgattga acaccattta ttcgaaacaa
    14521 gggactttga cacgactttt gtcacagtcc cttg
//
LOCUS       DAFBVQ010000066        14377 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.069, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000066 DAFBVQ010000000
VERSION     DAFBVQ010000066.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 14377)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 14377)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..14377
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.069"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            142..523
                     /locus_tag="LLC22_002278"
                     /pseudo
     CDS             142..523
                     /locus_tag="LLC22_002278"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303242.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            654..1604
                     /locus_tag="LLC22_002279"
     CDS             654..1604
                     /locus_tag="LLC22_002279"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002821555.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK5435533.1"
                     /translation="MLKTYSLTKDTLLVSSESNIKNSSVVYVYGDEREYIESSEHKYD
                     FKIGNILTFDDRVAYDTMIDKNDEKSLLVSFLFPEVHEGGHLDTLTTSVVFLVFKNKL
                     IIFTKQKLKFIPELLSNMVLRDVNHFVEEVLLKIMQKDFYMMLNDLRGVKEKIDDLDS
                     EISTSGSLKPTFGDLLTLQKYMIALSTTYKANHKALDFIKKNFTTIDDIDFSTKKIID
                     DLYDTSDTMDRIILSYSQYLDKLENMINNMISYQLNMIMKTLTEISIVLTIPAIIFGF
                     WGINVHVPFEKSSYGVLAVLIISAILSLICWLLMRRKTYL"
     gene            2122..2577
                     /locus_tag="LLC22_002280"
     CDS             2122..2577
                     /locus_tag="LLC22_002280"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303240.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5435534.1"
                     /translation="MVQQIVLPIKDSSVLKMVQDTLLDSFRAGRRNYTVFQVGKATLL
                     RVSDVMTLKKSDVYNPDGSVKNATFIHDKKTGKANTLYLKPVQQDLLQYHDWLAQENI
                     NSEWLFPSTAHYDLHITEKQFHKVMAHVGDLLGINLEDKEKKLRVRKPF"
     gene            2918..3520
                     /locus_tag="LLC22_002281"
     CDS             2918..3520
                     /locus_tag="LLC22_002281"
                     /inference="COORDINATES: protein motif:HMM:NF013878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435535.1"
                     /translation="MLDPLFTDETFITFGFGHLVELAEPGHYDEKWQNWKLESLPIFP
                     DRYDFEVAKDKGKQFKIVAELLKKANTIIVATDSDREGENIAWSIIHNANAFSKDKTF
                     KRLWINSLEKDVIRSGFQNLQPGMNYYPFYQEAQTRQIADWLIGMNASPLYTLNLQQK
                     GVQGTFSLGRVQTPTLYLIFQRQEAIENFKKEPFFEVEAK"
     gene            3614..3946
                     /locus_tag="LLC22_002282"
     CDS             3614..3946
                     /locus_tag="LLC22_002282"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308085.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase I"
                     /protein_id="HBK5435536.1"
                     /translation="MGNQEGIIADVQTKEKKTNSPSSFSLSSLQSKVNQLYKATASQT
                     LKAMQGLYEAKLLSYPRTDTPFITENEFAYLKANFGKYSGFLGLDLEMLLSLIMIRSN
                     NSTQILTN"
     gene            complement(4097..5076)
                     /locus_tag="LLC22_002283"
                     /pseudo
     CDS             complement(4097..5076)
                     /locus_tag="LLC22_002283"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332307.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            complement(5081..5848)
                     /locus_tag="LLC22_002284"
     CDS             complement(5081..5848)
                     /locus_tag="LLC22_002284"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209218.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR/GlpR transcriptional regulator"
                     /protein_id="HBK5435537.1"
                     /translation="MNKKRRLEKILDMLKIDGTITIKEIIDELDISDMTARRDLDALE
                     ADGLLTRTHGGAQLLSSKKPLEKTHIEKKSLNTKEKIDIAKKACSLIKDGDTIFIGPG
                     TTLEQLALELKGRKGYKIRVITNSLPVFLILNDSETIDLLLLGGEYREITGAFVGSMA
                     STNLKAIRFAKAFVSANAVTHNSIATYSDKEGVIQQLALNNAVEKFLLVDSTKFDRYD
                     FFNFYNLDQLDTIITDNQISPQHLEEFSQYTTILKAD"
     gene            6338..6763
                     /gene="lacA"
                     /locus_tag="LLC22_002285"
     CDS             6338..6763
                     /gene="lacA"
                     /locus_tag="LLC22_002285"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005237726.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacA"
                     /protein_id="HBK5435538.1"
                     /translation="MAIVVGADLKGTRLKDVVKNFLVEEGFEVIDVTKDGQDFVDVTL
                     AVASEVNKDEQNLGIVIDAYGAGPFMVATKIKGMVAAEVSDERSAYMTRGHNNSRMIT
                     VGAEIVGDELAKNIAKGFVNGKYDGGRHQIRVDMLNKMC"
     gene            6780..7295
                     /gene="lacB"
                     /locus_tag="LLC22_002286"
     CDS             6780..7295
                     /gene="lacB"
                     /locus_tag="LLC22_002286"
                     /EC_number="5.3.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012027025.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="galactose-6-phosphate isomerase subunit LacB"
                     /protein_id="HBK5435539.1"
                     /translation="MRIAIGCDHIVTDEKMAVSEFLKSKGHEVLDFGTYDHARTHYPI
                     YGKKVGEAVVSGQADLGVCICGTGVGINNAVNKVPGVRSALVRDMTSAIYAKEELNAN
                     VIGFGGKITGGLLMNDIIEAFIEAEYKPTEENKKLIAKIEHVETHNAHQADEDFFTEF
                     LERWDRGDYHD"
     gene            7306..8238
                     /gene="lacC"
                     /locus_tag="LLC22_002287"
     CDS             7306..8238
                     /gene="lacC"
                     /locus_tag="LLC22_002287"
                     /EC_number="2.7.1.144"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290553.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-6-phosphate kinase"
                     /protein_id="HBK5435540.1"
                     /translation="MILTVTLNPSVDISYPLETLKIDTVNRVKDVSKTAGGKGLNVTR
                     VLYESGDKVTATGFLGGKIGEFIESELEQSPVSPAFYKISGNTRNCIAILHEGNQTEI
                     LEQGPTISHEEAEGFLDHYSNLIKQSEVVTISGSLPSGLPNDYYEKLIQLASDEGVAV
                     VLDCSGAPLETVLKSSAKPTAIKPNNEELSQLLGKEVTKDIEELKDVLKESLFSGIEW
                     IVVSLGRNGAFAKHGDVFYKVDIPDIPVVNPVGSGDSTVAGIASALNSKKSDADLLKH
                     AMTLGMLNAQETMTGHVNMTNYETLNSQIGVKEV"
     gene            8241..9221
                     /gene="lacD"
                     /locus_tag="LLC22_002288"
     CDS             8241..9221
                     /gene="lacD"
                     /locus_tag="LLC22_002288"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290551.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBK5435541.1"
                     /translation="MVLTEQKRKSLEKISDKNGVISALAFDQRGALKRLMAQYQDTEP
                     TVAQMEELKVLVADELTKYASSMLLDPEYGLPATKALDKEAGLLLAYEKTGYDTSSTK
                     RLPDCLDVWSAKRIKEQGADAVKFLLYYDVDSSDELNQQKQAYIERVGSECVAEDIPF
                     FLEILAYDEEISDAGSVEYAKVKPRKVIEAMKVFSDPRFNIDVLKVEVPVNVKYVEGF
                     ADGEVVYSKAEAADFFKAQEEATNLPYIYLSAGVSAKLFQETLQFAHDSGAKFNGVLC
                     GRATWAGSVEPYIKEGEKAAREWLRTTGFENIDELNKVLVKTASPWTDKV"
     gene            9249..9566
                     /locus_tag="LLC22_002289"
     CDS             9249..9566
                     /locus_tag="LLC22_002289"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011669100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS lactose/cellobiose transporter subunit IIA"
                     /protein_id="HBK5435542.1"
                     /translation="MNREEMTLLGFEIVAYAGDARSKLLEALKAAENGDFAKADSLVV
                     EAGSCIAEAHNSQTAMLAREASGEELPYSVTMMHGQDHLMTTVLLKDVIHHLIELYKR
                     GAK"
     gene            9566..11272
                     /locus_tag="LLC22_002290"
     CDS             9566..11272
                     /locus_tag="LLC22_002290"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290549.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5435543.1"
                     /translation="MHKLIELIEKGKPFFEKISRNIYLRAIRDGFIAGMPVILFSSIF
                     ILIAYVPNAWGFHWSKDIETFLMTPYSYSMGILAFFVGGTTAKALTDSMNRDLPATNQ
                     INFLSTMLASMVGFLLMAAEPAKEGGFLTAFTGTKGLLTAFIAAFVTVNVYKVCVKNN
                     VTIRMPEEVPPNISQVFKDLIPFTVAVVLLYGFELIVKGTLGVTVAESIGTLLAPLFS
                     AADGYLGITLIFGAYAFFWFVGIHGPSIVEPAIAAITYANIDANLHLIQAGQHADKVI
                     TSGTQMFIVTMGGTGATLIVPFLFMWICKSERNRAIGRASVVPTFFGVNEPILFGAPI
                     VLNPIFFVPFIFAPIVNVWIFKFFVDTLNMNSFSANLPWVTPGPLGIVLGTNFQVLSF
                     ILAGLLVVVDTIIYYPFVKVYDEQILEEERSGKTNDALKEKVAANFNTAKADAVLGKA
                     GVAKEDVAANNNITKETNVLVLCAGGGTSGLLANALNKAAAEYNVPVKAAAGSYGAHR
                     EMLPEFDLVILAPQVASNFDDMKAETDKLGIKLAKTEGAQYIKLTRDGQGALAFVQQQ
                     FD"
     gene            11414..12820
                     /gene="lacG"
                     /locus_tag="LLC22_002291"
     CDS             11414..12820
                     /gene="lacG"
                     /locus_tag="LLC22_002291"
                     /EC_number="3.2.1.85"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phospho-beta-galactosidase"
                     /protein_id="HBK5435544.1"
                     /translation="MTKTLPKDFIFGGATAAYQAEGATHTDGKGPVAWDKYLEDNYWY
                     TAEPASDFYHKYPVDLELAEKYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHNLFAE
                     CHKRHVEPFVTLHHFDTPEVLHSDGDFLNRENIEHFVDYAAFCFEEFPEVNYWTTFNE
                     IGPIGDGQYLVGKFPPGIQYDLAKVFQSHHNMMVSHARAVKLYKDKGYKGEIGVVHAL
                     PTKYPYDPENPADVRAAELEDIIHNKFILDATYLGHYSDKTMEGVNHILAENGGELDL
                     RDEDFQALEAAKDLNDFLGINYYMSDWMQAFDGETEIIHNGKGEKGSSKYQIKGVGRR
                     IAPDYVPRTDWDWIIYPEGLYDQIMRVKNDYPNYKKIYITENGLGYKDEFVDNTVYDD
                     GRIDYVKKHLEVLSDAIADGANVKGYFIWSLMDVFSWSNGYEKRYGLFYVDFDTQERY
                     PKKSAHWYKKVAETQVIE"
     gene            12843..13115
                     /locus_tag="LLC22_002292"
     CDS             12843..13115
                     /locus_tag="LLC22_002292"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007209209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3884 family protein"
                     /protein_id="HBK5435545.1"
                     /translation="MLSDTLEKVQHLFRPGFEKVYIVSFEDCPMIPELEATPLLKCGK
                     WYVSTGKEWICHSDLELSAFEWEFLQSLDVEIRETIHFEVNYLPFQ"
     gene            13136..14035
                     /locus_tag="LLC22_002293"
     CDS             13136..14035
                     /locus_tag="LLC22_002293"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002889672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aldose 1-epimerase family protein"
                     /protein_id="HBK5435546.1"
                     /translation="MTIELKNEYLTVQFKTLGGQLTSIKDKDGIEYLWQADPNYWNGQ
                     APILFPICGSLRNDWAIYRPQERPFFTGLIRRHGFVRKEEFILEEVNDNSVTFSIKPN
                     AEMLDNYLYQFELRVVYTLNGKSIRTEFQVTNLEMEKTMPYFIGAHPAFNSPLVEGEN
                     YEDYYIEFSEVESCSIPKSFPETGLLDLQDRTPFLENQKILDLDYSLFSHDAITLDQL
                     KSRSVTLRSRKSGKGLRVDFDDFPNLILWSTTNKSPFIALEPWSGLSTSLEEGNFLED
                     KRQVTKISPQETSRKIYDITILN"
BASE COUNT         4695 a         2371 c         2771 g         4540 t
ORIGIN      
        1 gcgtttgatt ttcaaacttc gcaacagaac cgatgacact atcgttcttc atcaacgtaa
       61 gttagatttg ttgaaagagc agaaaaaagg atttctacaa aaaatgtttg tttgatattt
      121 taaatagaaa agagagataa agtgaagttt ttaaattttt tgaactataa atatttaaac
      181 tgggtattat atggtattac attatttttt attatttatt acttttttac cgatgatgat
      241 atttttttaa ttttagcaat actttttctt gtttcatcta attttagtga taacttaatt
      301 gaagttctta cagaaccaga aattcggtct atgacggatg aagaacaaca gattattaaa
      361 gctatgattt cggaaaataa gaaagacgta gtagttatca aaaagattag agagtataca
      421 aatttaggtg ttttacaagc caaaaaagta tatgaaaaaa aaaaaaaggg tctataatta
      481 caaattagat aatacattag aagctggaga caagattgtc tagataatgt gtgagataaa
      541 atttttggca ggttatcata cataagacaa aatgttttta aaactgataa cgtatttatt
      601 ccacaacaat tacgcattta tttctgagaa aaatataaag caggaggatt acaatgctga
      661 aaacttattc cttaacaaaa gatacattat tagtttcgtc agaatcaaat atcaaaaatt
      721 cttctgttgt ttatgtttat ggtgacgaac gagaatatat cgaatcttct gaacataaat
      781 atgactttaa aataggcaat atactaacgt ttgatgatcg agttgcatat gacacgatga
      841 tagataagaa cgatgaaaaa agtttgctcg taagtttttt gtttcccgag gtacatgaag
      901 gtgggcatct agataccctg acgacatctg ttgttttctt ggtatttaaa aataagttga
      961 taatttttac aaaacaaaaa ttaaaattca ttcccgaact cttatccaat atggttttac
     1021 gtgatgtcaa tcatttcgtg gaggaagtac ttttaaagat catgcaaaaa gatttctata
     1081 tgatgcttaa cgaccttcgt ggagtcaagg aaaaaattga tgatttagac tcagaaatat
     1141 caacgtccgg ttcactcaaa ccaacgtttg gtgatttatt gactcttcaa aaatacatga
     1201 tagctttgtc aacaacttat aaagctaacc ataaagcgct tgatttcatt aaaaaaaatt
     1261 tcacaactat tgacgatatt gattttagta ctaaaaaaat aattgatgat ttatacgata
     1321 caagtgatac aatggataga atcattttaa gttacagcca atatttggac aaattggaaa
     1381 atatgataaa caatatgatt tcgtatcagc taaacatgat tatgaaaacc ctaaccgaga
     1441 tatcaattgt tttgactatt ccagcaatta tttttggctt ttggggaatc aatgtccatg
     1501 tcccgtttga aaagtcttct tatggtgttt tagccgtatt gattatctct gctatactaa
     1561 gtctaatttg ctggcttttg atgcgacgca aaacatattt gtaaagtatt tgtgataccc
     1621 taatatgatt taaagcagaa tttctttgtt gactttttaa aaggctgatt cctttcaata
     1681 atttaatagc ttcagcggct gctcagaagt caataaattg gactattttt attcagttac
     1741 ttaggcaaca tttgagatac gattgcgatt ataaaaattg atataccaac caatggctgc
     1801 ttggaagact gacatattag cctcgatatc atcgaataac taaatacaga aaaatacaat
     1861 aaatattatc aaactaggga ctatactaga aaacatcagt acattcctta actcagggtc
     1921 tataattaga aaatcgcccc tttgaaaact gattaaaaca gcccccatta tctagtgact
     1981 agataatggg ggctgttttt ttgttaagtg atataataaa ccataaaaga agtttagaaa
     2041 tacggtcctg gtcatcaata aataaacaat ttaattaatt atttatttaa ttatttaatt
     2101 tcagaaaggt atacatgaat catggtgcaa caaattgtcc tacccatcaa agactccagc
     2161 gtcttaaaga tggtacaaga tacacttctc gatagtttcc gtgctggtcg ccgaaattac
     2221 accgtttttc aagttggtaa ggccacgcta ctacgtgtga gtgatgtcat gacattaaaa
     2281 aaatcagatg tctataatcc agacggctct gtcaaaaatg caacctttat tcatgataaa
     2341 aagaccggta aagcaaacac gttatattta aagcctgttc agcaagactt gttgcaatat
     2401 catgattggc tggcccaaga aaatatcaat tctgagtggt tatttccctc gacagcccat
     2461 tatgatcttc atatcactga gaagcagttt cataaggtga tggcgcatgt tggtgatctc
     2521 ttaggaatca acttggaaga caaagagaaa aaattgcgag tcagaaaacc gttttgagat
     2581 atgaacagca tttgccttca cgccttagcg attttaaata atagccttga aagtgattat
     2641 ggaaaagccc tctacgctca atgcaaaatt gacgtagaaa ctatttttga tcgattgaaa
     2701 ggtgtatttg gtatgtgaag aacccatgtc agaggcaaga acgttgcacc tactgacatt
     2761 ggaatgatgc ttatgagcat gaatctaacc aaattatccc ttgaggctag aagaaaagcg
     2821 gaagcttttc aacacaaagc agccaaaaat aaaaaacgcg acgaagcaat cacatttatg
     2881 attattcatc gcgtttttta tatttagagc tagttatttg ctagacccac tatttacaga
     2941 tgaaacgttt atcacctttg gttttgggca tttagtggaa ttagcagaac caggtcatta
     3001 tgacgaaaag tggcaaaatt ggaaacttga atctttgccg atttttcctg atcgatacga
     3061 ttttgaagtt gcaaaagata agggaaagca gtttaaaatt gttgcagaac ttctcaaaaa
     3121 ggcaaataca attattgttg caacagatag cgacagagaa ggtgaaaata tcgcctggtc
     3181 gattatccat aatgcaaatg ccttttcaaa agataaaaca tttaaaagac tatggatcaa
     3241 tagcttagaa aaagatgtga tccgaagcgg ttttcaaaat ttgcaaccag gaatgaatta
     3301 ctatcccttt tatcaagaag cgcaaacacg ccaaattgcc gattggttga tcggcatgaa
     3361 cgcaagccct ttgtatacgt taaatttaca acagaagggc gtacaaggta cattttcact
     3421 aggacgtgtt caaacgccca ccttatacct tatttttcag cgccaggaag ccatagagaa
     3481 ttttaaaaaa gaaccttttt tcgaggtgga agctaagtaa aacaagggtc atttaagggc
     3541 gttctaagcc ccacacagcg ttttaaaacc caagaggagc tttttagctt ttgtttcttc
     3601 taaacaagct aaaataggca atcaagaggg gataattgct gatgttcaaa ccaaagagaa
     3661 gaaaacgaat agtccgagtt cgttttcttt aagtagtttg caatcaaaag tcaatcagct
     3721 ttataaagcg acagcgagcc aaactttaaa agctatgcaa ggactgtatg aagcaaaatt
     3781 attgagttat ccaagaacag atacaccatt tattacagag aacgaatttg cttatttaaa
     3841 agcgaatttt ggcaaatata gcggtttttt aggacttgat cttgaaatgt tgttatcatt
     3901 gataatgata cgttcaaaca acagcaccca aattttgacg aattagtgaa actctatgaa
     3961 aaagacgtag taaaacatgc aacatcctat tctaatcagc tggtaaagct taattaggtt
     4021 atataagctt gaaaataaag ggtttgtcca atatggacaa gcctttttct tatgttttgc
     4081 cacagatttg ccacacttat tgtgtaagag tatcaaggat aggtataatt tgatactttg
     4141 tttttttagt gatgtgcaaa taaatttctg ttacacgact acctctagaa tgccctacac
     4201 ggtcttgaat tgcttctagg ggtattcctt actctgctaa gaaactaata tgcgtatgac
     4261 ggaatatatg ggtcgtaata tgtttattaa aactaagttt attatcaata tcaattcctg
     4321 ctcgttttgg attacctttt cgatttaatt ttccattttc aggtgagttg aggaaattgt
     4381 taaggacact ataatgaaga ggtgttccat tatagtcggg tttatgacga cttttggaag
     4441 taaaaatcca tccattatct ttataatcag gattgaatct catatgttgg tgatttaact
     4501 caatttcctc tttaagaatt tctatagccc ttttagataa ttggacattt cggtaacttt
     4561 gtaagttttt tacattacct tcatagctat tttctgcagc tcctccgtga gtggactgac
     4621 taatgatgat attttgcttt tcaaaatatt gataggcacc aatattttgg agtttcgact
     4681 ctgtaagtca acagggccat tagttagaat acctattggg atgcggtttt tatgtagagc
     4741 cagcagtagt tgatgtatct caggaatcat cgtaatctga tcgagttcat attcatagtc
     4801 agcttggaag tctagagctt ctgtcctaga aatactatcg atgccaaatt cttccatagt
     4861 cttctgacag cgaaaaattc taagctgctc aatactgatg agttttttcg tgtatttagg
     4921 aaaagcaaca tcagaccaat atctgaaacg tttgtaaatg ttatctattt gttggatatc
     4981 aatcgttgga aaacatttct caacgctacg tttaaagggg agttgatggt cataaagagt
     5041 gtcatcaagg tcaaaaacaa tatttttata agtcataatt ctagtccgct tttaaaatag
     5101 tagtgtactg gctaaattcc tctaagtgtt gagggctaat ctggttatct gtaatgatgg
     5161 tatcgagttg atctagatta tagaagttaa agaaatcgta tcgatcgaat ttagtactgt
     5221 ctactaataa gaatttttct acagcattgt ttagggcaag ttgttgaatc acaccttcct
     5281 tgtcactata tgtagcaata gaattatggg taacagcatt tgcactaaca aaagctttgg
     5341 caaatctaat tgcttttaaa tttgtcgaag ccattgaacc tacaaaagct ccagttattt
     5401 ctctatattc accgccaaga agcaataaat caatggtttc gctatcattt agaatcaaga
     5461 acacagggag actatttgta atgacacgaa ttttataacc tttacgacct ttcaattcta
     5521 atgccagttg ttcaagtgta gttccaggtc caataaaaat agtatcgcca tctttgatta
     5581 aagagcaggc ttttttagca atgtcaattt tttcttttgt atttagactt ttcttctcga
     5641 tatgtgtctt ttcaagtggc tttttagagg aaagcaattg tgcaccacca tgagtacgtg
     5701 ttaaaagtcc atcagcttct agagcatcaa ggtctctacg ggctgtcata tcggaaatat
     5761 ctagttcatc tattatttct tttatggtta tggtcccatc aatctttaac atatctaaaa
     5821 ttttttctaa tcgtcgtttt ttgttcatat gaagaccctt ctttcataaa gtaatttttt
     5881 tccaaagata attctctttt aattgtatca taaaagacaa tattttcaag gtaaaacaaa
     5941 caatttcaaa caaaaacaaa tgttagatga tgaaataaga acagaggatt gacgtatatt
     6001 agcttaggtc agattttgta taagacgaaa ataaagtagg acctcttaat cagtaagtta
     6061 tagaaagtaa aagacttttg taatacttga atagatattt cacgtccatt ttgtgatgga
     6121 ttaaatgaac aaaaatgaac aataatttaa cggtgttatc tattttttaa aaaaacaaat
     6181 aaaaaaaaca aaaaataaac aaaaaaagtg ttgctttttg tttgaatgct tgatattata
     6241 taaacaaaga aatgatgaaa acgttttttc gaacattttg caaaatgttt tctacttcta
     6301 cgtagcattt ctttctaaaa tttaggaggt ggtcaaaatg gctattgttg ttggtgcaga
     6361 tctcaaaggt acgagattaa aagatgttgt gaaaaatttt cttgtagaag aaggttttga
     6421 ggtaattgat gtgactaagg acggacaaga ttttgttgat gttaccttgg cagttgcctc
     6481 tgaagtaaat aaagatgagc aaaacttagg tattgtaatt gatgcttatg gagctggtcc
     6541 attcatggta gcaactaaaa ttaaaggtat ggttgcagca gaagtttcag atgaacgctc
     6601 agcttatatg acacgtggac ataacaattc acgaatgatt acggttggcg ctgaaatcgt
     6661 cggtgatgag cttgctaaaa acatcgctaa aggtttcgtc aatggtaaat atgatggcgg
     6721 acgtcatcaa atccgagtag atatgcttaa caaaatgtgt taagaaaagg agttaaggaa
     6781 tgagaatcgc aattggatgt gaccacattg tcacagatga aaaaatggca gtatcagaat
     6841 tcttgaaatc aaaaggacat gaggtccttg atttcgggac atatgaccac gcacgtactc
     6901 actaccctat ctatggtaaa aaagtcggtg aagcagtagt aagtggtcaa gcagacttgg
     6961 gagtatgtat ctgtggtaca ggtgtcggca ttaacaatgc agtcaataaa gttccaggtg
     7021 ttcgctcagc gttggttcgt gatatgacat cagctatata tgcaaaagaa gagttaaatg
     7081 cgaatgttat cggtttcggt ggaaagatta ctggtggtct tcttatgaat gacatcattg
     7141 aagctttcat tgaagctgag tacaaaccaa cagaagaaaa taaaaaattg attgcaaaaa
     7201 tcgaacacgt tgaaacacat aatgcacatc aagcagatga agatttcttt acagaattcc
     7261 ttgaaagatg ggaccgtggt gactaccacg attaaggtat aacaaatgat tctgacagtc
     7321 acactaaatc cttcagtaga catctcttat cctctagaaa cattgaaaat tgatacagtg
     7381 aatagggtga aagatgttag taagacagct ggtggaaaag gcttaaatgt tactagagtc
     7441 ttgtatgaat ctggtgataa agttactgct acaggtttct taggtggtaa aattggtgaa
     7501 tttattgaaa gcgaattaga acaatctcct gttagtccag ctttttataa aatctcagga
     7561 aacactagaa actgtattgc tatcttacac gagggtaacc aaacagaaat tttggaacaa
     7621 ggaccaacaa tttctcatga agaagcagaa ggctttcttg accactatag caatcttatt
     7681 aaacaatcag aagttgtgac aatttcagga agtttacctt caggacttcc caacgattat
     7741 tatgaaaaac ttatccaact tgcttcggat gaaggagtag cagtcgtttt ggattgttca
     7801 ggtgcacctc ttgaaacagt tctaaaatcg tcggctaaac ctactgccat caaacctaat
     7861 aatgaggaac tttcacagtt gcttggaaaa gaagtaacaa aagatattga agaactcaaa
     7921 gacgttctta aagagtcact ttttagtggt atcgaatgga tagtggtctc attaggtcga
     7981 aacggtgcct ttgcaaaaca tggtgatgtt ttctataagg tagatattcc tgatatccca
     8041 gttgttaatc cagtcggatc aggggactca acggtagctg gtattgcatc agctttaaat
     8101 agtaaaaaaa gtgacgctga cttattaaaa catgcgatga cattgggtat gttaaatgct
     8161 caagaaacaa tgacagggca tgtgaatatg actaattacg aaacactaaa ctcacaaatt
     8221 ggagtaaaag aggtataaaa atggtactta cagaacagaa acgcaaatct ttggaaaaaa
     8281 tttcagataa aaacggtgtt atctcagctt tggcatttga ccaacgtggt gctttgaaac
     8341 gtttgatggc acagtatcaa gatacagaac caactgtagc tcaaatggaa gaactaaagg
     8401 ttttggttgc tgatgaactt acaaaatacg cttcttcaat gttgcttgac cctgaatatg
     8461 gacttccagc aacaaaagca ttggataaag aagcaggtct tcttcttgcc tatgaaaaaa
     8521 caggttatga tacatcaagt acaaaacgtt tgcctgactg cttggatgtt tggtctgcaa
     8581 aacgtatcaa agagcaaggc gctgatgccg ttaagttctt gctttactat gatgtagaca
     8641 gctcagatga acttaaccaa caaaaacaag cttatattga acgtgttggt tctgaatgtg
     8701 tcgctgaaga tattcctttc ttcttggaaa tccttgctta tgatgaagaa atctcagatg
     8761 caggttctgt tgaatatgca aaagtgaaac ctcgcaaagt cattgaagcg atgaaagttt
     8821 tctctgatcc acgctttaac attgatgttc ttaaagtaga agtaccagtt aacgttaaat
     8881 atgtcgaagg ttttgctgat ggtgaagtag tttacagtaa agctgaagct gctgacttct
     8941 ttaaagcaca agaagaagcg actaaccttc catacatcta cctaagtgca ggtgtatctg
     9001 ctaaattgtt ccaagaaaca ttgcaatttg ctcacgactc aggtgccaag tttaatggtg
     9061 tgctttgtgg acgtgctact tgggcaggat ctgtagaacc ttacatcaaa gaaggtgaaa
     9121 aagcagcacg tgaatggttg cgtactactg gattcgaaaa tattgatgaa cttaacaaag
     9181 ttcttgttaa aacagctagt ccatggactg ataaagtata gtaaaaacat aaaacggagg
     9241 atattgttat gaacagagaa gagatgactc tcttagggtt tgaaattgtt gcttatgctg
     9301 gagatgctcg ctctaaactt ttagaagcgc ttaaagcggc tgaaaatggt gatttcgcta
     9361 aggcagatag tcttgtagta gaagcaggaa gctgtattgc agaggctcac aattctcaga
     9421 cagctatgtt ggctcgagaa gcttctgggg aggaacttcc atacagcgtt accatgatgc
     9481 atggtcagga ccacttaatg actactgtct tattaaaaga tgtgattcat cacctcatcg
     9541 aactttataa aagaggagca aaataatgca taaactcatt gaacttattg agaaagggaa
     9601 accgttcttt gagaaaatct ctcgaaacat ctatcttcgt gctattcgtg atggatttat
     9661 cgctggtatg ccagtcatcc ttttctcatc tatctttatc cttattgcct atgtcccaaa
     9721 tgcttgggga ttccactggt caaaagacat tgagaccttc ttgatgactc cttatagcta
     9781 ttcgatgggt atcctagcat tctttgttgg tggtactacc gctaaagctt tgacggactc
     9841 aatgaaccgt gacctacctg cgaccaatca gattaacttc ttatctacga tgctagcgtc
     9901 tatggtaggg ttccttttga tggcagctga gcctgcaaaa gaaggaggct tcttgacagc
     9961 cttcacggga acaaaaggtc ttttgacagc atttattgca gcctttgtga cagttaatgt
    10021 ttacaaggtc tgtgtgaaaa ataatgttac tattcgtatg cctgaagagg ttccaccaaa
    10081 tatctctcaa gtatttaaag acttgattcc attcactgta gcggttgttc tcctttatgg
    10141 atttgaactc attgttaagg gaactcttgg tgtaaccgtt gcagaatcaa tcggtaccct
    10201 tcttgctcct ctcttctcag ctgcagatgg ttaccttgga attacactta tctttggtgc
    10261 ttatgccttc ttctggtttg ttggtatcca cggtccttca attgtcgaac cagcaatcgc
    10321 tgctatcact tatgccaata tcgatgccaa cttgcatctt atccaagctg gacaacatgc
    10381 agacaaagtt atcacttctg gtactcaaat gtttattgtt accatgggtg gaacaggagc
    10441 tacattgatt gttccattct tgttcatgtg gatttgtaaa tcagaacgta accgtgccat
    10501 cggacgtgcc tcagttgttc caacattctt tggggttaat gagccaatct tatttggtgc
    10561 accaatcgta ttgaatccga ttttctttgt accgttcatt ttcgctccga ttgtcaacgt
    10621 ttggatcttt aaattctttg ttgacacatt gaacatgaac tcattctctg ccaaccttcc
    10681 atgggttact cctggtccgt tgggaattgt actcggtact aacttccaag ttctatcatt
    10741 tatcttagcc ggactcttgg tagttgttga tactatcatt tattacccat ttgttaaggt
    10801 atacgatgaa caaattcttg aagaagaacg ttctggtaaa acaaacgatg ctcttaaaga
    10861 aaaagtagct gcaaacttca atactgctaa agcagatgcc gttcttggaa aagcaggcgt
    10921 tgctaaagaa gatgtagcag caaacaataa tatcacaaaa gaaactaatg tccttgttct
    10981 ttgtgcaggt ggaggtacaa gtggcttgct tgccaatgcc ttgaacaaag cagcagcaga
    11041 atacaatgtt ccagtcaaag cggcagcggg tagttacggt gctcaccgtg aaatgttgcc
    11101 agagtttgac ttggttatct tggctccaca ggtcgcttca aacttcgatg atatgaaggc
    11161 tgaaacggat aaattgggca ttaaacttgc aaaaactgaa ggagctcaat atatcaaatt
    11221 gacacgtgat ggacaaggtg ctcttgcatt tgttcaacaa cagtttgatt aataaatttg
    11281 taaaagttat ttgagacgag attattcttt caattcctta taatattgtt aaccatatca
    11341 ttgcatttca tttccttggt ttccggaact cagaatatcg tctcaaatgc tttttttgaa
    11401 aggatttata gttatgacta aaacacttcc taaagatttt atttttggtg gtgctacagc
    11461 tgcttatcaa gcagaaggtg cgactcacac ggatggtaaa ggcccagttg catgggataa
    11521 gtatcttgaa gacaattatt ggtacacagc agagcctgca agtgattttt accataaata
    11581 tcctgttgat ttagaattag ctgaaaaata tggcgttaat ggtattcgta tttcaattgc
    11641 ctggtctcgt attttcccaa ctggctatgg cgaagtaaat gaaaaaggtg ttgaattcta
    11701 ccataatctt tttgccgagt gccacaaacg tcatgttgag ccattcgtga ctttgcacca
    11761 ctttgacaca ccagaagttc ttcactcaga tggagatttc ttaaaccgcg aaaatataga
    11821 acactttgta gattatgccg ctttctgttt tgaagagttc ccagaagtaa actactggac
    11881 aactttcaat gaaattggcc caattggaga tggtcaatac ttggttggta aattccctcc
    11941 aggcattcaa tatgatcttg ccaaagtctt ccaatcacac cacaatatga tggtttctca
    12001 tgcacgtgct gtgaaattgt ataaagataa aggttataaa ggcgaaattg gtgtagtaca
    12061 tgcgttgcca accaaatacc cttatgatcc agaaaatcca gcagatgttc gtgccgctga
    12121 gttagaagat atcatccata acaaatttat cttggatgca acctaccttg gacactattc
    12181 agataaaacg atggaagggg tcaaccacat cctagctgaa aatggtggag aacttgatct
    12241 tcgtgatgaa gacttccaag cacttgaagc agctaaagat ttgaacgatt tccttggtat
    12301 caactactac atgagtgatt ggatgcaagc ctttgatggt gagactgaaa tcattcacaa
    12361 tggtaagggt gaaaaaggaa gttctaagta ccagattaaa ggtgttggtc gccgaatcgc
    12421 accagattat gtgcctagaa cggattggga ctggattatt tatcctgaag gcttgtatga
    12481 ccaaatcatg cgagtgaaaa atgattatcc aaactacaag aagatttaca tcactgaaaa
    12541 cggtcttgga tacaaagatg agtttgtaga taataccgtt tatgatgatg gtcgtattga
    12601 ttacgtgaag aaacacttgg aagttttatc agacgcaatt gcggatggtg caaatgttaa
    12661 aggttacttc atctggtcac ttatggatgt cttctcatgg tcaaacggat acgaaaaacg
    12721 ttatggacta ttctatgtag actttgacac gcaagaacgc tatcctaaga aatcagctca
    12781 ttggtataag aaagtagcag aaactcaagt gatagagtaa tattacttga aaatgtaaaa
    12841 aattgttatc cgatacttta gaaaaagtac aacacttatt tagaccaggc tttgaaaagg
    12901 tatatattgt tagtttcgaa gattgtccta tgattcctga gcttgaagct accccgttgc
    12961 taaaatgtgg taaatggtat gtttcaactg gaaaagagtg gatttgccat tctgatttag
    13021 agttatcagc atttgaatgg gaatttttac aatcactcga tgtagaaata cgtgagacta
    13081 ttcacttcga ggtaaattat ttgcctttcc aataataaaa agaaaggaat tagttgtgac
    13141 tatcgaatta aaaaacgagt atcttactgt tcagtttaaa acacttggtg gtcaactgac
    13201 ttcgattaaa gacaaggatg ggatagagta tctctggcaa gctgatccaa attattggaa
    13261 tggacaggcg cctattctat ttcctatctg tggtagttta cgaaatgatt gggctattta
    13321 tagacctcaa gaaagaccct tttttacagg tcttattcgt agacatggtt ttgttcgaaa
    13381 agaagaattt attctggaag aagtcaatga taatagcgtg acctttagta ttaaaccaaa
    13441 tgctgagatg cttgataatt acctatatca gtttgaactg agagttgttt ataccttgaa
    13501 tggtaaatca attagaaccg aatttcaggt aacgaacttg gaaatggaaa aaacaatgcc
    13561 ttactttatt ggagcccatc cagcattcaa tagtccttta gtagaaggtg aaaactatga
    13621 ggattattat attgaattta gtgaggttga gtcttgctcg ataccaaaga gttttcctga
    13681 gacaggatta ttagatttgc aagatcggac accttttttg gaaaatcaaa aaattctcga
    13741 tttggactac tcactttttt cccatgatgc cattacactt gaccagctca agtctcgtag
    13801 cgtaacgctt cggtcaagga agtctggtaa aggtcttcga gtagattttg atgattttcc
    13861 gaacttgatt ctgtggtcta caactaataa aagtccattc attgctttgg aaccttggag
    13921 tggtctctcc acttcacttg aagaaggtaa tttcttagaa gataaaagac aggtaacgaa
    13981 aatttcacct caagaaactt ctagaaaaat ctatgatatt actatcctta attaaaattt
    14041 gttattattt gagtcttcaa taagatttga atactcttac cttgtgatga tagattggtc
    14101 ttctccgtgc cagtcttaca tcgcaaggtt tttaagtttt ttgtgggtct atgtcaactg
    14161 tagtgggtga cgaaaagcta atatctaaag acagtctggt agtaaaaaat aagattattt
    14221 actacttctt gatttaaaat aatagtggag ccattaattt gtggcaaatt taatttaata
    14281 ttttgcctca aattagccac actttttata gaactaagag gaaaaatgaa attttcttcc
    14341 tattaatata gttgtttgaa atcttaaata tagcgtt
//
LOCUS       DAFBVQ010000067        13488 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.070, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000067 DAFBVQ010000000
VERSION     DAFBVQ010000067.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.070"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(164..388)
                     /locus_tag="LLC22_002294"
     CDS             complement(164..388)
                     /locus_tag="LLC22_002294"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287661.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="flagellar motor switch protein"
                     /protein_id="HBK5435547.1"
                     /translation="METEWQRRERKKQKKEEMLRLCRLLDVKDWDKNEQIAQKVRSII
                     HKEEKVKNKDTRRTENEKRKVQKKREKSKS"
     gene            complement(586..2166)
                     /locus_tag="LLC22_002295"
     CDS             complement(586..2166)
                     /locus_tag="LLC22_002295"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290823.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide chain release factor 3"
                     /protein_id="HBK5435548.1"
                     /translation="MNNPKLKQQVDNRRTFAIISHPDAGKTTITEQLLLFGGAIRQAG
                     TVKGKKTGNFAKSDWMEIEKQRGISVTSSVMQFDYQGKRVNILDTPGHEDFSEDTYRT
                     LMAVDSAVMVIDSAKGIEAQTKKLFQVVKKRGIPIFTFINKLDRDGREPLELLEELEE
                     LLDIESYPMNWPIGMGKGLEGLYDIYHNRVEFYRPENYQDERLVELDEDGLLPENHPL
                     TENSLYEQVLEEVELIKEAGDAFNQEKIARGDQTPVFFGSALTNFGVQTFLETFVELA
                     PAPYGHKTQDDQMVSPYEEEFSGFVFKIQANMNPAHRDRIAFVRICSGTFERGMDVWL
                     ERTNKKLKLSNVTQFMADSRENVEKAVAGDIIGVYDTGNYQIGDTLFEGKLKVAYEEL
                     PSFTPELFMKVTAKNVMKQKSFHKGIYQLVQEGAIQLYKTYLTEEYIIGAVGQLQFEV
                     FQYRMLNEYNAEVIMSPMGHKIARWIDPEDLDEKMSSSRNILARDRFDQPLFLFENQF
                     AERWFADKYPNVKLKSLM"
     gene            complement(2567..3943)
                     /locus_tag="LLC22_002296"
     CDS             complement(2567..3943)
                     /locus_tag="LLC22_002296"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610209.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HlyC/CorC family transporter"
                     /protein_id="HBK5435549.1"
                     /translation="MNADPESQSLLAQILLLIVLTLINAFLAASEIAVVSINKNRIEQ
                     KADEGDVKSQKLLKILQNPNNFLSTIQVGITLVNILSGASLANTLSERLAPVLGGGTA
                     AKNIANIIVLAILTYVSIVFGELYPKRIALNKSEEVAKFTSGLIRLIGVVAKPFVWLL
                     SASTSLLARITPMTFDDEDSKMTRDEMRYMLENEGVLNNEELEMLQGVFSLDTKVARE
                     VMVPRTDAFMIDINDTVEENVNEVLSENYSRIPVYNEDKDKVVGILHTKNLLKAAHKF
                     GFDNLDIKKIMQEPLFVPETVFIDDLLYEMKKTQNQMAILLDEYGGVVGLATLEDLLE
                     EIVGEIDDESDEVENLYEKIDEHEYIIQGRMLIDEFNEAFDSDLHMSDVDTMAGYLIT
                     ALGMIPDEGEKLSFDVDNITLVSEEMEGSRILKIRVIFHDPEETEAEPEEERRYFRKE
                     FEDDEPRR"
     gene            complement(4071..5189)
                     /locus_tag="LLC22_002297"
     CDS             complement(4071..5189)
                     /locus_tag="LLC22_002297"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341268.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AI-2E family transporter"
                     /protein_id="HBK5435550.1"
                     /translation="MFEKLRQSKLMFWSLELLIIAALIMISSEINFIFEPIGTFFSTL
                     FAPVLIAGFLYYLLNPIVKLLMKAKIKRIWAVAIVLLLLVAAIIWILLSVIPSLVQQI
                     SSLASNMPDFIKQVESWLKEVAELPLFKEVDINKYFEQLDISYGTIIQQFLSGVSNSL
                     GSIVGTIASATVVIITAPFILFYMLKDGEKLVPNIQQFFPEKRRNQIVELLGQLNKTL
                     ANYISGQAIECLFVGTFTFLGYMVIGVDYAFLFGVIAGLTNLIPYLGPYLGLAPAFLV
                     TVFNDPVKALLCCVVVLIVQQLDGNIIYPNVIGKSLKIHPLTIIIVLLVAGNIAGLLG
                     IFLGVPFYAICKTIISYIIKIVKEDKQNENKKKIATTS"
     gene            5331..5765
                     /locus_tag="LLC22_002298"
     CDS             5331..5765
                     /locus_tag="LLC22_002298"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310346.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5435551.1"
                     /translation="MKVVQTKDTMSNIYLDAVRIRHQVFVVEQGVPLSREIDKDEAHC
                     IHFVLYSDKKEPQGTVRLLPLENGKMKLQRMAILSEYRHQGLGKILIEEAENFAKNQG
                     YNTILLGAQSTAETFYEKLGYTAYGDPFEDAGMPHIYMKKTL"
     gene            complement(5843..6376)
                     /locus_tag="LLC22_002299"
     CDS             complement(5843..6376)
                     /locus_tag="LLC22_002299"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336938.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF402 domain-containing protein"
                     /protein_id="HBK5435552.1"
                     /translation="MGVPKEGEFVTIQSYKHDGKLHRTWRDTMVLKTSEHSMIGVNDH
                     TLVTESDGRRWVTREPAIVYFHKKYWFNVIAMIREKGVSYYCNLASPFLLDDEALKYI
                     DYDLDIKVFPDGEKRLLDVDEYEMHSKMMNYPNDIDFILKENVKILVDWINNGDGPFS
                     EGYIDIWYNRYKQLSRK"
     gene            complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="LLC22_002300"
     CDS             complement(6470..7648)
                     /gene="mutY"
                     /locus_tag="LLC22_002300"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="A/G-specific adenine glycosylase"
                     /protein_id="HBK5435553.1"
                     /translation="MNKEWEKWTDKETKEFQDQFIQWYEQEKRNLPWRYNRDPYRIWI
                     SEIMLQQTRVDTVIDYFYRFMEWFPTIEELANAPEEKLLKAWEGLGYYSRARNIQAAA
                     KQIMSEFDGEMPQTPEEISSLKGIGPYTTGAIASIAFGLPEPAVDGNVMRVVSRLFCI
                     EADIAKASSRKIFDEAMRKIIDEKHPGEFNQAMMDLGSAICTPTSPKCETCPIQAFCL
                     ANKRGIQTSFPVKTKKAKPKDVYYISAALQNHSGAYYFEERDSQKLLANMWTFPMMEV
                     TQEEYERLKKEWETKPEIDLFDDLVAEEEQNLPFEKQELFVWQTRHLGEVTHIFSHLK
                     WHVLLFYGRATEGAEQEFTENKTSKWLKPDAFDSVVFPKVQMKLVDQLEKNRNNRNPF
                     "
     gene            complement(7641..8438)
                     /gene="recX"
                     /locus_tag="LLC22_002301"
     CDS             complement(7641..8438)
                     /gene="recX"
                     /locus_tag="LLC22_002301"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327148.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombination regulator RecX"
                     /protein_id="HBK5435554.1"
                     /translation="MLTVTRISKGKGPFYRVDLSEGEALQVSEDVLVRYRLLKGRELD
                     EETIQEIKKSSGADFGFHLAMNYLSYQLRSEKEIRTYLKEKEILQEDRNKIVARLKEL
                     DLVDDLVYGESYVRTNMRLSDKGPKKLAQQMQQKGLKPEIIEQALSQYTFEDQVQNAH
                     QTAEKAFGKNHGKSQKELLRKIQQTLMTKGFSQEVIQQAIADLPQEADQEIEYDYLVK
                     QGDKLWRRNLRFEPKKRNLKVKQSLYQKGFDLDMIQRFITEKEEESE"
     gene            8545..9927
                     /gene="rlmD"
                     /locus_tag="LLC22_002302"
     CDS             8545..9927
                     /gene="rlmD"
                     /locus_tag="LLC22_002302"
                     /EC_number="2.1.1.190"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (uracil(1939)-C(5))-methyltransferase
                     RlmD"
                     /protein_id="HBK5435555.1"
                     /translation="MAETIVKTGQTVPLKIKRLGINGEGIGYFKRLIIFVPYALPKEE
                     VLVKITKATPRYAEGELIKVKKTSKDRVVAPCPVYYECGGCQLQHLAYQAQLDFKKDL
                     LLQALEKFKPAGFRSYQLLPTIGMDEPWHYRNKAQFQLRKNKQTQKIEAGLYEANSHQ
                     LVPITDCLVQEPRTQKVMNTVVQLLNKFDAPIYDERTNSGIFRTIMVRIGVKTGELQV
                     VFITRSKKFPQKNAMIREINERLPEVVSIMQNVQAQKTSLVMGDETIHLWGKEAIEEQ
                     INEVTFDLSPRAFFQLNPQQTELLYGEGIKALDVQPNETIVDAYCGVGTIGLSVAKQA
                     KEVRGMDTVPQAIADAKKNAERLGYHNTRYEVGTAEQVLPKWLNEGFQPDGIIVDPPR
                     TGLDNALIQSLLKYPPKKLVYISCNVSTLARDLVNLSKKFKIEYLQSVDMFPQTARCE
                     VVVKMTRLAD"
     gene            complement(10101..10679)
                     /locus_tag="LLC22_002303"
     CDS             complement(10101..10679)
                     /locus_tag="LLC22_002303"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lytic polysaccharide monooxygenase"
                     /protein_id="HBK5435556.1"
                     /translation="MKKISTLLFIGLVSLGLFGFSIPGFAHGYITSPGSRAYLGTSAA
                     GNLNQNVGRAQWEPQSIEATKNTFIDGKIASAGVSGFEPLDEQTSNRWHKNMVNPGTL
                     NITWNLTAQHRTSTWDYYITKPTWNPNQPLKFSDFELITKIDDKATVPPKTVNQTITL
                     PQDRKGYNVILAVWNISDTTNAFYQVIDVNIQ"
     gene            11001..11471
                     /locus_tag="LLC22_002304"
     CDS             11001..11471
                     /locus_tag="LLC22_002304"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629457.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tryptophan-rich sensory protein"
                     /protein_id="HBK5435557.1"
                     /translation="MKMIKDIRFWVCVIGIVILGFLSGLLSGNPGKYYYSLQLPPFAP
                     PSWIFGPMWTLLYILMGISLYLLLNHNNKKQRNNLVGLFVIQFIFNFIWSALFFNLRN
                     IFIAAIDITLLVIFLSVLMYQLWLHHRLAMWLMIPYYLWVLFATLLNYSIYFLN"
     gene            complement(11579..12805)
                     /locus_tag="LLC22_002305"
     CDS             complement(11579..12805)
                     /locus_tag="LLC22_002305"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322158.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5435558.1"
                     /translation="MKRWQKVLLTLLGVFVLLIAGLSAYGIRFMGEASQTVNKISKNS
                     NRISSKRSERVSIDDKEPFSVLLLGLDTGGLGRTEQGRSDTMMVVTVNPKQKKSTIIS
                     LDRDIYTNIVGYGTVDKLNHAYAFGGVEMAMDSIEQLLDIPIDHYVTINLDGMEDLIN
                     AVGGIKVNNKIDFTLDGVHVPVGEQTLNGEKGLAYSRMRHEDPEGDIGRQRRQREVVT
                     KIVNKVLSLDGVSNYRKILKAVENNVTTDLDWDDMLDVATNYTPAFETIKQDQLQGEG
                     QMINDIYYQILGKNDLLSIQNELKKQLNIKTSDTLPNLKNENASMMFFDDSEDGDSTN
                     GDGSNSEGYTDYSSYSENTYDQYQDPNTYYQQTEDTSQYYTPSQDTQSYDPYAGQEQN
                     GYGYDQNNEYGTTSGY"
BASE COUNT         3960 a         2719 c         2248 g         4561 t
ORIGIN      
        1 taaagaacac ttttgtctca cgctctaaac acgtataaac ggcgaaagca gaagcaactc
       61 cttcggaaat aagctgaaat tcacgaaaat tgcttttcaa atttttgtga attccagctt
      121 atttcttgga gttaaacgct tctgtctcag cctctttttc tttctagctt tttgattttt
      181 ctcttttctt ttgtactttt ctcttttcat tttcagttct acgcgtgtct ttatttttaa
      241 ctttttcctc tttatggatg attgatcgta ctttttgtgc aatttgctcg tttttgtccc
      301 agtcttttac atctaataat cgacataatc gtaacatctc ttcttttttc tgtttttttc
      361 tttcacgtct ttgccattct gtttccatgt gtcacactct cctttcttta atcatatgta
      421 cgcaaaataa tttttatatt tttttgatta gacatttcta tgattttaat atagtaaaaa
      481 gagccgtcac ggaaaatccg tcacggctct aaacaaaata tgagaggctg tttttgtttg
      541 gctattctta ttacttgatg cagggcagct tgtgtcaaga cttctttaca tcaaactttt
      601 taattttaca ttgggatatt tatccgcaaa ccagcgttct gcaaattggt tctcgaataa
      661 gaacaacggt tggtcgaaac ggtcacgagc caagatattg cgacttgaac tcatcttctc
      721 atccaaatct tctggatcga tccagcgagc gattttgtgt cccattggag acatgattac
      781 ttcggcgtta tactcattta acatacgata ttggaatact tcgaattgta gctgaccaac
      841 agctccaatg atatattctt ccgttagata tgttttataa agctgaatcg ctccttcttg
      901 aactaattga tagattcctt tgtggaagga tttttgtttc atgacatttt ttgcagtcac
      961 tttcataaac agctctggag taaatgaagg gagttcttca taagcaactt ttagttttcc
     1021 ttcgaacaat gtatccccaa tctgataatt gcctgtatca tatacaccga tgatatcgcc
     1081 tgctactgct ttttcgacgt tttctctcga atctgccata aattgtgtga cattgcttaa
     1141 tttcagtttt ttatttgtac gttccaacca gacatccatt cctcgttcga atgttccaga
     1201 acagattcgg acaaaagcga ttcggtcacg atgggctgga ttcatatttg cttggatctt
     1261 gaatacgaaa cctgaaaatt cttcctcata aggacttacc atctgatcat cttgtgtttt
     1321 gtgtccataa ggagctggtg ccaattcaac gaaagtctct aaaaaagtct gtacaccgaa
     1381 gttagtcaat gcagaaccaa aaaatactgg tgtctgatcg ccacgagcaa ttttttcttg
     1441 attaaatgca tctccagcct ctttgattag ttctacttct tctaagactt gttcatataa
     1501 ggaattttca gttagaggat gattttcggg aagcagtcca tcttcatcca attctactaa
     1561 tcgttcatcc tgataatttt ccggacgata aaactctaca cgattatggt agatatcata
     1621 aagaccttct agccctttac ccataccgat tggccaattc atcggataag attcgatatc
     1681 taatagctct tctaattctt ctaacaattc caatggttca cgaccatcac gatctagttt
     1741 gttgataaaa gtaaatatcg ggatgccacg tttttttaca acttggaata atttctttgt
     1801 ctgtgcttcg atcccttttg cactatcgat taccatgacc gcactatcca cggccatcaa
     1861 agtacgataa gtatcttcag aaaaatcttc atgtcctggt gtatccaaga tatttactcg
     1921 tttcccttga taatcaaact gcataacaga actagtaaca gaaatcccac gttgtttctc
     1981 gatttccatc cagtctgatt tggcaaaatt acctgttttt ttgcctttta cggtcccggc
     2041 ttgacggata gccccaccaa acaatagtaa ttgttctgta atcgttgttt tcccagcatc
     2101 cggatgggaa atgatcgcaa aagttctgcg attgtccact tgttgcttta attttggatt
     2161 attcataacc taactccatt tcttccattc aattatttat attttctcta ggcacagatt
     2221 gtccgatctc ttaaagaaag acaatttcat atagggctgt gacaaaagcc gtgtagcagt
     2281 ctctttttcc gagtaaacgg cgttctagag acagcctatc agcaataagc ccacccaagc
     2341 caaaaatacg aaaagctgtt tttgcttggc tgctcttatt acttaatgca ggatagcttt
     2401 ttcacaacct ttgtcaacta ctacaactga atcagtatag catggattca gcgaatgaaa
     2461 aagccaccaa accataagag tcaaatattt ttttgtcagc tgactaaaag aaaagacgtg
     2521 ttgcttgttt attcaagcaa cacgtctttc ataaccaagt ttccaattat cttcttggct
     2581 cgtcatcttc gaattctttt ctgaagtatc ttcgttcttc ttcaggttcc gcttctgttt
     2641 cttccggatc atgaaaaatg acacggattt taaggattcg agaaccttcc atttcttcag
     2701 aaaccagcgt aatattatcg acatcaaacg ataacttttc gccttcatcc ggaatcatgc
     2761 ctaatgctgt aatcaaataa ccagccatcg tatctacatc actcatatgc agatcactgt
     2821 caaaagcttc attgaactca tcaatcagca tacgtccttg gatgatatat tcgtgttcat
     2881 cgattttttc ataaagattc tcaacttcat ctgattcatc atcgatttct ccgacgattt
     2941 cttctaaaag gtcttctagt gttgctaacc caacgacgcc gccatattca tctaataaaa
     3001 tagccatctg attctgcgtc tttttcattt catataacag atcatcaata aagaccgttt
     3061 caggaacgaa taaaggctcc tgcatgattt tcttgatatc taaattatca aagccgaatt
     3121 tatgggcagc ttttagtaaa ttctttgtat gaaggattcc gactacttta tctttgtctt
     3181 cgttataaac agggattctt gaatagtttt cggataaaac ttcattcaca ttttcttcca
     3241 cagtgtcgtt gatatcaatc ataaatgcat ccgttcgtgg gaccatgact tctcgggcaa
     3301 ctttcgtatc aagagaaaaa accccttgga gcatttctaa ttcttcatta ttcaatacgc
     3361 cttcgttttc aagcatataa cgcatttcat ctctggtcat ttttgaatct tcatcatcaa
     3421 aagtcatcgg cgtgatacgc gccaataaac ttgtggaagc agaaagcagc cagacgaagg
     3481 gcttagctac tacaccaatc aagcgtatca gccctgaagt gaactttgcg acttcttctg
     3541 atttatttaa agcaatacgt ttagggtaca attctccaaa aacaatcgat acataggtca
     3601 aaatagccag cacaatgata tttgcaatat tttttgccgc tgtgccgcca cctaataccg
     3661 gagctaaccg ttccgataaa gtattagcta gtgaagcacc agacaaaatg ttgaccaaag
     3721 tgattcctac ttggattgtc gataggaaat tatttggatt ctgcaatatt tttaaaagct
     3781 tttgagattt cacatctcct tcatcagctt tttgctcgat tcgattctta ttgatcgaaa
     3841 caacagcaat ttcggaagct gctaaaaaag cattgatcaa tgtcaaaacg atcaataata
     3901 aaatctgcgc taacagcgac tgactctcag ggtcagcatt cataatcgca ttctctcctt
     3961 ataaaattaa tttttagttt acgatagaaa aaaacgtggc actatagcca cgttaaaatg
     4021 gtatcacaaa gcaattttct ttgcaataaa aacaagtgta ctaaaactac ctacgaggtc
     4081 gtagcaattt tcttcttgtt ttcattttgc ttgtcttctt tgacgatttt gattatatag
     4141 gaaatgatcg tcttgcagat tgcgtaaaaa ggaacaccta agaagatacc aagcaatccg
     4201 gcaatatttc cagctactag aagaacgata atgatcgtta atggatggat tttcagtgat
     4261 ttcccaatta cattaggata aatgatattc ccatccaact gttggacgat tagcacaacc
     4321 acacaacaaa gtaatgcttt taccggatca ttgaagactg ttactagaaa tgcaggtgct
     4381 agtcctagat aaggtcctaa atatggaatt aggtttgtca atcccgcaat gaccccaaat
     4441 aagaaagcat aatccacacc aattaccata tatcctaaaa atgtgaaggt accaacgaat
     4501 aaacattcga ttgcttgtcc gctaatgtaa ttagccaatg ttttattcag ttgccccaat
     4561 aactccacaa tttggtttct tcttttttct gggaaaaact gttggatgtt tggcactagt
     4621 ttttctccgt ctttcaacat atagaacaag atgaatggtg ctgtaatgat tactacggtt
     4681 gccgaagcga tcgttccaac gatcgaacct aaactattgg atactccact aaggaattgc
     4741 tgaatgattg tcccgtaaga aatgtctaat tgctcaaaat atttattgat atctacttcc
     4801 ttgaacaaag gcaattcggc tacctctttt aaccagcttt ctacctgttt gatgaaatca
     4861 ggcatattag atgccaatga ggaaatttgc tgtactagac ttgggatgac actaagtaaa
     4921 atccaaataa ttgctgcaac taaaaggagc agcacaattg cgacagccca tattcttttg
     4981 atttttgctt tcatcaacag cttgacaata ggattcaata aatagtaaag aaagcctgca
     5041 atcagtacag gtgcaaataa cgtggaaaaa aatgtcccga tcggttcgaa aataaagttt
     5101 atttctgatg aaatcatgat caatgcagct atgatcaata attcaagcga ccaaaacatt
     5161 agtttagact gtctaagttt ttcaaacaat agatttcctc ctttctttct tactagtata
     5221 tattatattc gttaaaaatt cttttattct ttttttattt ttgaaaactt gccatacttt
     5281 ttatttgttt tattttccag tatactatac gaaaggaagg tggctagacc atgaaagttg
     5341 tacaaacaaa agatacaatg agcaatattt acttagatgc tgtacggatc aggcatcaag
     5401 tttttgtagt cgaacagggt gtgcctttgt ctcgagaaat agacaaagat gaagcccatt
     5461 gtatccactt cgtcctgtac tcagataaaa aagaaccgca aggaactgta cgtcttttgc
     5521 ctttagaaaa cggaaaaatg aaattacagc ggatggcgat tctttctgaa tacagacacc
     5581 aagggttagg aaaaatattg attgaagaag cagaaaactt tgctaagaat caaggctata
     5641 atacgatttt attaggggca cagtccacag ctgaaacttt ttacgaaaaa ctaggatata
     5701 cagcttacgg cgatcctttt gaagatgctg gcatgcctca tatttatatg aaaaagactt
     5761 tataaaaatt tatttcgaaa aaagcaaaaa acagcaagct tttgagaaaa atctctcact
     5821 ggcttactgt tcttttttgt gtttacttac gcgacaattg cttgtaacgg ttataccaaa
     5881 tatcaatata gccttccgag aacgggccat ctccattatt gatccagtca accagaatct
     5941 tcacattttc ttttaggatg aagtcaatat cgttcgggta attcatcatt ttgctgtgca
     6001 tctcatattc atcgacatcc aatagtcgtt tctcgccgtc aggaaatacc ttgatatcca
     6061 agtcatagtc gatatatttc aaggcctcat cgtccagcaa aaaaggtgaa gctagattac
     6121 aataatagga aacccccttt tctctgatca ttgctattac attgaaccag tattttttat
     6181 gaaaataaac aatcgctggt tcgcgcgtta cccatcggcg tccatcagat tcagtgacta
     6241 atgtgtgatc attcacgccg atcatagagt gttcgcttgt ttttaatacc atggtatctc
     6301 gccacgttcg atgcaatttg ccgtcgtgct tgtaactttg gatcgtcaca aactctcctt
     6361 cttttggaac tcccatagca acccttcctt aagcagcatt ttgtgctttg tgtttgggtg
     6421 ttcattacac cgacatcata attattatat caataaaaat gagctttgcc tagaaaggat
     6481 tcctattgtt tcgatttttc tctaactgat ctaccagttt catttggacc ttaggaaaaa
     6541 cgaccgaatc aaatgcatca ggcttcaacc acttcgaagt tttgttctcg gtaaattctt
     6601 gttctgctcc ctcggttgcc cgtccgtaaa aaaggagaac atgccatttc agatgactaa
     6661 aaatatgagt aacttctcct aaatgtcgtg tctgccaaac aaagagttcc tgcttttcaa
     6721 atgggagatt ttgctcttct tctgctacta ggtcatcaaa cagatcgatt tctggctttg
     6781 tttcccattc ttttttcaat cgctcatact cctcttgtgt cacttccatc attggaaatg
     6841 tccacatatt cgccagcaat ttttggctat ctctttcttc aaaataatac gctccagaat
     6901 gattttgaag agctgcactg atataataaa cgtcttttgg ctttgctttt tttgttttta
     6961 caggaaaact cgtttggatt cctcgtttgt tagctaaaca aaaggcttgg atcggacaag
     7021 tctcacactt tggagaagtt ggtgtacaga tagctgaacc tagatccatc attgcttggt
     7081 tgaattcacc tggatgcttt tcatcaatga ttttccgcat cgcttcatca aagattttcc
     7141 tgctagaagc ttttgcgatg tctgcttcaa tgcaaaacaa tctgctgact actcgcatca
     7201 cgttgccgtc aactgcaggt tctggaagtc caaatgcgat acttgcaatc gcgcctgtcg
     7261 tatatggtcc tattcccttc aatgagctaa tttcttcagg cgtttgcggc atttccccat
     7321 caaattctga catgatctgt ttagcagcag cttggatgtt ccgggctctt gagtaataac
     7381 caaggccctc ccatgctttt aaaagctttt cttctggagc atttgctagc tcttcaattg
     7441 taggaaacca ttccatgaaa cgataaaaat aatcgatcac tgtgtctact ctggtttgct
     7501 gaagcatgat ctcagagatc cagatacgat aaggatcacg attatagcgc caaggcaggt
     7561 ttcttttttc ttgttcatac cattgaatga actgatcttg aaattctttt gtttctttat
     7621 ctgtccattt ttcccattct ttattcactt tcctcttcct tttccgtaat gaatcgctgg
     7681 atcatatcca aatcaaatcc tttttgatat aagctttgct ttacttttag atttcttttt
     7741 ttaggttcaa accttaaatt tcttcgccat agtttatctc cttgtttgac taaataatca
     7801 tattctattt cttgatctgc ttcttgcgga agatcagcta tcgcttgttg gatcacttct
     7861 tgagaaaagc ctttcgtcat caatgtttgt tggatttttc tcaataattc tttttggctt
     7921 tttccgtgat tttttccaaa cgctttttcg gctgtctgat gtgcattttg aacttggtct
     7981 tcaaatgtat attggctgag cgcttgttca atgatttcag gtttcaaacc tttttgctgc
     8041 atctgctgcg ctaatttctt tggtcctttg tcacttaagc gcatattcgt gcgcacataa
     8101 ctttccccat agaccaaatc atcgacaagg tccaattctt ttaagcgggc tacgatttta
     8161 tttcgatctt cttgaaggat ttccttttct tttaagtatg ttcggatttc tttttccgat
     8221 cgcaactgat aacttaagta attcattgct aggtgaaaac cgaaatcagc tccgctactc
     8281 ttcttgatct cttggatagt ttcttcgtct aattcccgtc cttttaataa tcgatagcgt
     8341 actaatacat cttcagatac ttgtaaagct tctccttcag ataaatctac gcgatagaaa
     8401 gggcctttgc ctttactgat tctcgtaacg gttaacataa acatcctcct cgaacatata
     8461 ttctctatca taccacagaa aatccccgta atcaggtatt atatgttaga ataaaccaca
     8521 gaaaaaagaa aaagggagat acttatggca gaaacaattg tcaaaactgg acaaacggtt
     8581 cctttgaaaa tcaagcgttt aggcataaat ggtgaaggaa tcggttattt caaacggttg
     8641 atcatatttg ttccatatgc actaccaaaa gaagaagtac tagtgaaaat cacgaaagca
     8701 actcctcgct atgcagaagg agaattaata aaagtcaaaa aaacaagcaa agatcgcgta
     8761 gtggcaccat gtcctgttta ctatgaatgc ggtggctgtc aattacaaca cttagcttat
     8821 caagctcaat tggattttaa aaaggatctg cttttgcaag cattggaaaa attcaaacca
     8881 gcaggctttc gatcttatca acttttgccg acgatcggga tggatgagcc ttggcattat
     8941 agaaacaaag cacaatttca gttacgaaaa aataagcaga ctcaaaaaat tgaagctggt
     9001 ttatacgaag caaactctca tcagttagtc cctataacag actgcttggt tcaagaacct
     9061 cgaacacaaa aagtaatgaa tactgttgtt caactattga ataaatttga tgcacccatc
     9121 tatgatgaac ggacaaacag tggaatcttc cgcacaatca tggttagaat cggtgttaaa
     9181 actggggagt tacaagttgt ttttattact cgcagtaaaa aattcccgca aaaaaacgca
     9241 atgatccgtg agatcaatga acgactgccc gaagttgttt caatcatgca aaatgtccag
     9301 gcacaaaaaa cgtctctcgt gatgggggat gaaacgatcc acttatgggg aaaagaagcc
     9361 attgaagaac aaatcaatga agtgactttc gatctttctc ctcgtgcctt ctttcaactc
     9421 aatcctcagc agaccgaatt gctttatggc gaaggaatca aagcattaga tgtccagcct
     9481 aatgaaacga tcgtggatgc ttattgcgga gttgggacga tcggcttaag tgtagcaaaa
     9541 caagccaaag aagtacgggg aatggatacc gttcctcaag caatcgctga tgcaaaaaaa
     9601 aatgcggaaa gattaggata tcacaacact cgatatgaag tcgggacagc agagcaagtt
     9661 ctgcctaaat ggttgaatga aggttttcag cctgatggta tcatcgtaga tccaccacgt
     9721 acgggtttgg ataacgcatt gatccaatca ttattgaaat accctccaaa aaaacttgtt
     9781 tatatctcct gtaatgtttc tacacttgcc agagatctgg ttaatttaag taaaaagttc
     9841 aagattgaat atttacagtc cgtcgacatg tttcctcaga ctgcacgttg tgaagttgtc
     9901 gtgaagatga cgagactcgc tgactaaatg aaagaggttg tgaaaaagtc tgccctgtat
     9961 caagtaataa gaacagccaa acaaaaatag ctcttcatgt tttatgaata ctgtacttgt
    10021 gaccgaagag ttaacaggag gacactattt attaaaaaaa agggttgtga catagttttt
    10081 gtcacagccc tttttgatta ttattggata ttcacgtcta tcacttgata aaatgcattt
    10141 gtcgtatcgc tgatattcca tactgctaaa atcacattat atccttttcg atcctgcgga
    10201 agtgtgatcg tttggttgac tgtttttggt ggaacagttg ctttgtcgtc tatttttgtg
    10261 atcaattcaa aatcactaaa tttcaaaggt tgattaggat tccaagttgg tttggtaatg
    10321 tagtaatccc aagtacttgt ccgatgttgt gctgttaaat tccaagtaat atttaatgtt
    10381 cctggattaa ccatgttttt atgccatctg ttagatgtct gttcatctaa aggctcaaag
    10441 ccgctgactc ctgcactagc aatttttcca tcaatgaatg tatttttggt agcttcgata
    10501 ctttgcggtt cccattgtgc tcttccgaca ttttgattta agtttcctgc tgctgatgtt
    10561 cctaggtatg cacggcttcc tggagaagta atataaccat gcgcaaaacc tggaatgcta
    10621 aaaccgaaca accctaaact aactaaccca ataaacaata acgtactaat ctttttcatg
    10681 tagaaacctc cttcatttga taaccacatt gtaaacgctt tattgtatta acacaaacat
    10741 tatgctttta taattttatg ttgaagtaaa aaaggtgaaa aaagtaagat gcagattata
    10801 acagaagtag acgagaaaag tacaaataga aaacatgaga atcaaatcat atgatctttt
    10861 tcaaaaacat cattcatata aacaaatgtt caacttttta ataacaacaa ttatcaattt
    10921 ttttcttact tcacaaacta aatacaggtc ttgctgtgag ccttcatggt aaactaatat
    10981 tatagaaagg agttagtaaa atgaagatga taaaagatat tcgtttttgg gtttgtgtta
    11041 taggaattgt catattaggc tttttatcag ggttgcttag cggaaatccc ggaaaatatt
    11101 actattcttt gcaacttcca ccatttgcac cacctagctg gatatttggg ccgatgtgga
    11161 ccttactgta tatattgatg ggtatttctc tttatttgtt acttaatcac aacaacaaaa
    11221 aacagcgaaa caatcttgtc ggtctttttg tgattcagtt catttttaat tttatatggt
    11281 ctgctctatt ttttaattta agaaatattt tcattgcagc aatcgatatt acacttttag
    11341 ttattttctt gtcagtgctt atgtatcagt tgtggctgca tcatcgcctg gcaatgtggc
    11401 tcatgattcc ttattattta tgggtactat tcgcaactct attgaattat tcaatttatt
    11461 ttttaaacta agcgctaaaa agagacgtcc tgtaatttaa cacatagaaa aagtgccacc
    11521 taagttagat tttttgtcta atttaggtgg cactctttat taaccaaact atttttttct
    11581 agtacccact tgttgttcca tactcattat tctggtcata accataacca ttttgttcct
    11641 gtccagcgta aggatcataa ctttgagtat cttgacttgg tgtatagtac tgacttgtat
    11701 cttctgtttg ctgataatag gtattcggat cttggtactg atcatatgtg ttttctgaat
    11761 aggaagaata atcggtgtac ccttcactat tcgatccatc accgtttgtc gaatcgccat
    11821 cttccgaatc atcaaagaac atcattgaag cattctcatt tttcaaatta ggtaatgtat
    11881 cgcttgtttt tatatttaat tgtttcttca gttcattttg gatcgaaaga agatcatttt
    11941 ttcctaaaat ttgatagtag atatcattga tcatttgtcc ttcgccttgc aactggtctt
    12001 gtttgattgt ttcaaacgcc ggggtgtagt tcgtcgctac atcaagcatg tcatcccaat
    12061 ctaagtccgt cgtcacattg ttctcaactg cttttaaaat ttttctataa ttgcttacgc
    12121 catctaaact taaaacttta ttgacgattt tcgtcactac ttcccgctga cgacgttgtc
    12181 gaccgatatc gccttctgga tcttcgtgtc gcattcgaga ataggctaaa cctttttctc
    12241 cattcaatgt ttgttcacct actggtacat ggacaccatc caaagtaaag tcaattttat
    12301 tattcacttt gatgccaccg accgcattga tcaaatcttc catgccatcc aaattgatcg
    12361 ttacataatg atcaatagga atatcgagca gttgctcaat tgaatccatg gccatttcga
    12421 caccaccaaa tgcgtaggca tgatttaatt tatctaccgt tccataacct acgatattcg
    12481 tataaatatc tcggtccaaa ctgatgatcg ttgatttttt ttgtttcgga ttaactgtta
    12541 ctaccatcat cgtatcagaa cgtccttgtt ccgttcttcc taatccaccg gtatctaaac
    12601 ctaatagcaa aaccgaaaaa ggttctttgt catcaatgct tactctctca gaacgtttgg
    12661 aggatattcg attagagttt ttagaaattt tgtttactgt ttggctcgct tctcccataa
    12721 atctgattcc gtatgctgat aatccggcaa tcagcaaaac gaatacccct aacaaggtta
    12781 atagaacttt ttgccatcgc ttcataatac acctctgttt cacattttct aaaatattgt
    12841 ctcatataac tgttcaatca gcaaattcac tttttaatca taagaaaact ttaaaaaaca
    12901 tttttgtgta acgattatta ttttttaaaa tttctcaaaa ttcttaacta tcataccata
    12961 ccgtgaaaaa gatcgaaaga ccgaatacac gcagttcgca atcgttttat ctttttttat
    13021 gtattttttc cagaaaaagc gaacaacaag gtattttcca aataatcgtg cagtaaaatg
    13081 atcgcacata cctttcccat ctttttaaca gtctttgcct accgttcaga ttatcattcg
    13141 atttcacgac aatttcttcc tatgactggt ccttttgtta aacccatctt ctattcgttt
    13201 tatttccagc tcactgcatg gctcttaaaa tgactcgaac tagtgattgc attaccatca
    13261 tcttttaatg gatagatatg ctcctcttca aagtaaaacg attttctttt aaagtaatag
    13321 aattgacatg gtaatgagta tgtatactag tggtttcaca aatggtcttt tattcaacat
    13381 ccaaaaactg aaatttcttt aaaatccatt actaacgaag aaaatgttcc ttgcttgata
    13441 attagttagg acatgtcaag tgaacaaatg catttactta gccaaaaa
//
LOCUS       DAFBVQ010000068        13427 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.071, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000068 DAFBVQ010000000
VERSION     DAFBVQ010000068.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13427)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13427)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13427
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.071"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..912)
                     /locus_tag="LLC22_002306"
     CDS             complement(<1..912)
                     /locus_tag="LLC22_002306"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_042964654.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine synthase family protein"
                     /protein_id="HBK5435559.1"
                     /translation="MIISTITEAIGSTPLYRFDNQHYSMPKGSAIYAKLEYLNPGGSI
                     KDRLGSYLIKEGFAQGKINEKTTIIEPTAGNTGIGIALAALTYKLRTVFVVPEKFSLE
                     KQQLMKALGAKIIHSPSEQGIIGAISKSKKLAEEISNSYLPLQFENKDNPAAYYHTLG
                     PEIFHEIKENIHSFVAGIGSGGTFAGTSTFLKEKYPDIRIIGVEPEGSVLNGGDPAPH
                     EIEGIGVEFIPPFLSPLSINQIETISDVEGFNYTRQLAREQGLLVGSSSGAAFAAALR
                     EIRRLPPGHRVVTIFPDAADRYLSKNIY"
     gene            1340..1903
                     /gene="efp"
                     /locus_tag="LLC22_002307"
     CDS             1340..1903
                     /gene="efp"
                     /locus_tag="LLC22_002307"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010751911.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor P"
                     /protein_id="HBK5435560.1"
                     /translation="MISASDLRAGMTFVQDGKLIKVLDASHHKPGKGNTVMRMKLKDV
                     RSGATYDTTFRPEEKFEKAHIDTKPVQYLYTMDDTAFFMDLETYEQYEIPVETVEEEM
                     KYILENMEVKIQFFGSEVIGVQLPTTVVLRVVETQPSIKGATVTGSGKPATMETGLVV
                     NVPDFIETDELLEINTAEGSYVKRASK"
     gene            2004..2174
                     /locus_tag="LLC22_002308"
     CDS             2004..2174
                     /locus_tag="LLC22_002308"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435561.1"
                     /translation="MKNKKVFDFIYILKDEWQKLEKEKTALIYEEIEMIHKIENIRTI
                     PNYIEAKIFFHH"
     gene            2389..3648
                     /gene="lysA"
                     /locus_tag="LLC22_002309"
     CDS             2389..3648
                     /gene="lysA"
                     /locus_tag="LLC22_002309"
                     /EC_number="4.1.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301232.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate decarboxylase"
                     /protein_id="HBK5435562.1"
                     /translation="MTELIIGGVTASTLAEKYKTPLYVYDEEKMRQTMLSFKRGFVSK
                     RFDTKVLYASKAFQTIEMLHLVREYGFGLDVVSGGEIYTALQADFPRDTIYFHGNNKT
                     PEELIYALENDLLHIVADNLMEVELLAELSQRYLKKICIMLRLNVGVEAHTHEYIVTA
                     HIDSKFGMSYESKECQQALQLIKESSYLELEGFHAHIGSQIFDVTAWLAEIDKLTNYL
                     TDFDQPLSLNLGGGFGIRYTQNDQPIPVEEALKKLIEYTEEALEKRKLTIRQLLIEPG
                     RSIVGEAGTTLYTIGFIKKTPHKKYYFVDGGMTDNIRPALYQAEYDCDLAAKLSEEKT
                     EKVTIAGKMCESGDVVIKEAYLPKAESGDLLAVYSTGAYGYSMSSNYNRATRPAVVFV
                     NNGQSRLIVRRQAFSDLLRGEVSYDPS"
     gene            3635..4435
                     /gene="dapF"
                     /locus_tag="LLC22_002310"
     CDS             3635..4435
                     /gene="dapF"
                     /locus_tag="LLC22_002310"
                     /EC_number="5.1.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291395.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diaminopimelate epimerase"
                     /protein_id="HBK5435563.1"
                     /translation="MILHKYNGCGNDFILLDYAEDTDYSQLAASLCTKEKYDIDGLIA
                     VKIDPLEMIYYNKDGSRAPMCGNGIRCFARYVNDQNMMNEQEFNVETLAGTRKITVLD
                     PSPFYCSVDMGVPDDSPEKIKANQTYPIKNQEIEINGEKVTITSLFLGTIHTVVFVEN
                     AREEVWRKRGELICHHPLFKEKTNVNFVEVVNEQELIVRTYERGVGWTLACGTGCCAS
                     YVVAKETGKISADQVVVHLEQGDLMISGEDAIQMAGPAVHEWTRILEE"
     gene            4438..5319
                     /locus_tag="LLC22_002311"
     CDS             4438..5319
                     /locus_tag="LLC22_002311"
                     /EC_number="4.3.3.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate synthase"
                     /protein_id="HBK5435564.1"
                     /translation="MIKGSIVALITPMNEEGSVDYAGLEKLIQFHLDEQTDGLLVLGT
                     TGESSTLTQSEEEQILQLTVKKVAGRVPVIAGAGTNNTKETIEKAKHFASLGADALLV
                     ITPYYNKTSDAGLAAHFTAIAEASPIPLILYNVPSRTGMSIPIHVLVNLAEHPNIIGL
                     KEASGDMAYVMDAARLIGEEFFLYSGNDDLILPVMSVGGSGVISVWANIQPKIVHELV
                     KDTQDGRWQQAKEKQLNALELIHALFSETNPIPVKAAMSLLDLPSGPLRLPLVSLSKE
                     KKKQLAQLLLKERTVEK"
     gene            5316..6032
                     /locus_tag="LLC22_002312"
     CDS             5316..6032
                     /locus_tag="LLC22_002312"
                     /EC_number="1.17.1.8"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002345386.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-hydroxy-tetrahydrodipicolinate reductase"
                     /protein_id="HBK5435565.1"
                     /translation="MKIGLIGSGQMGNRVEEVAQERGDTVLLLRTAPKEATTLAFTEL
                     PELLIDFSHPDNLEKILSYSLSYQLPLVIGTTGYTQSQFQEIKEHAKHVPVMYSANFS
                     FGIMVMNQLIKQAAAMLQGWQIELIEKHHSRKKDAPSGTANMLLQTIQEVQKLQPVYN
                     WQGKKREENQIGVHSIRAGSLPGEHDVLFAATDEIFTIKHESFSNRIFAAGAVEAADW
                     LKDQSPGYYKLEDLLMDKGV"
     gene            6038..6733
                     /gene="dapD"
                     /locus_tag="LLC22_002313"
     CDS             6038..6733
                     /gene="dapD"
                     /locus_tag="LLC22_002313"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338548.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2,3,4,5-tetrahydropyridine-2,6-dicarboxylate
                     N-acetyltransferase"
                     /protein_id="HBK5435566.1"
                     /translation="MEAQEIIRYIQTASKKTPVKVYLNVTEPIEFKESKVFGEGSSFV
                     VFGDYETIAPVLEAESEKIIEIEIETAARYSAVPLLDIKKINARIEPGAIIRDQVSIG
                     NNAVIMMGAIINIGAVIGENTMIDMGAVLGGRATVGKNCHIGAGAVLAGVIEPASAKP
                     VIVEDGVLVGANAVIVEGVHIGKDAVVAAGAVVLEDVAAETVVGGIPARVLKISDDQT
                     KENTALIAALREL"
     gene            6749..7750
                     /locus_tag="LLC22_002314"
     CDS             6749..7750
                     /locus_tag="LLC22_002314"
                     /EC_number="1.2.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate-semialdehyde dehydrogenase"
                     /protein_id="HBK5435567.1"
                     /translation="MREIDTCIVGATGLVGQTMLKVLEEYDFPVGRLKLLASKRSAGK
                     VCVFKKKKHTVQELTETSFEGYDLALFSAGASVSKEFAPIARSQGLFVIDNSSAWRED
                     SDIPLIVPEVNLEDYTLNRLIANPNCSTIQAVLPLKALQEAFGIQRVNYSTYQAVSGS
                     GQKGIEDLHRTQNDEKPVLYPYNISQTVIPEIDQPLENGYTKEEQKMINETRKILHQP
                     ALPVSATCVRVPIENGHGVSVAVQLQKEFTTEEIRECLSQFPGIQLEDDLAAHKYPTS
                     ILARGTDMVYVGRIRKDTSLENGLLFYTTADNIRKGAAANAVQIAAALMQKIAEVAR"
     gene            7747..9108
                     /locus_tag="LLC22_002315"
     CDS             7747..9108
                     /locus_tag="LLC22_002315"
                     /EC_number="2.7.2.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate kinase"
                     /protein_id="HBK5435568.1"
                     /translation="MSNTLKVAKFGGTSMSHEEQFKKVRTIVLSDPNRQVIVVSALGK
                     RTSDDDKVTDLLYLIYAYLQHHVDWTPLWKRICDRFIQVRDVLALQLPIEDELARIQK
                     QLEDEKITEDYLVSRGEYLTAQLMAEYLGYQFIDAKDLIFFDYDGKIDQEKTAQEITK
                     AFKRYPKMVVPGFYGANPAGKEKLLGRGGSDITGAILAKMLQAESYENWTDVSGIMMA
                     DPRIIDHPKIIEEISFRELREMAYMGANVLHEAAVFPVQEADIPIQIKNTNDPFAQGT
                     KISNHEIEKENGLTGIAGRKDFLSITLFKRHMSDEIGFIWKAMSIFAKHEISIEHIPS
                     GIDNIGVIVSAEAIADKLFLITKELKETLGVEEIVVIEDLALISVVGGPHKELIGLSG
                     KVLSILNKLEIRTSILSQGAQELNLIIGVPNNQYETVVKGIYEGMVNTDAERISNGTP
                     SNS"
     gene            9068..10219
                     /locus_tag="LLC22_002316"
     CDS             9068..10219
                     /locus_tag="LLC22_002316"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amidohydrolase"
                     /protein_id="HBK5435569.1"
                     /translation="MLKEYRMALHQIPEIGFHEFKTKKYLYEQVKNSEAVIHEIGETG
                     LLLYFDNQQEETIAFRTDIDALPVKEETNLSFASKHEGYMHACGHDGHMAMLLGLTDF
                     ITKHIEDLIYNVVLIYQPSEEISGGAQSVIQSGLLDKYEVQAIFGFHLWPGLAKGEVF
                     SRPGPLMAQSSETDIIIKGQSAHIASSEKGIDSLEAAVRFLKNVYDFDRQLPAEWNHL
                     MKFGQIQGGTIRNVLAGEVIVSGSIRSYSSDMQNYLKRGLDHLAEQFHSTATISFRYN
                     DGYPAVINHRGLYAALLDSNKLHELDAPVLQAEDFGIYTQQYPCVFFFLGVGDTPALH
                     DPTFDFDMDVLENGVEWYKTILFTENLLVKIDSSSKEERVNNDEFIQSI"
     gene            10194..11363
                     /locus_tag="LLC22_002317"
     CDS             10194..11363
                     /locus_tag="LLC22_002317"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5435570.1"
                     /translation="MMNLSNRFSPRLSRIEVSKIRQFDQQISSIPDVIKLTLGEPDFP
                     TPEHVKQAGIAAIEEDFSHYTGMRGLEELREAACIFQQQRYGLTYDPQTEVLTTVGAT
                     EAIASALLSVLEEGDKVLIPAPAYSGYQPLVELAGAELIPIDTSDTGFVCQPEQFERA
                     FEQYGSAVKAVILNYPNNPTGTTLSAKQLKAIAEVLKKYPVFVISDEVYAELTYSGTH
                     MSIATYLPEQTIVISGLSKSHAMTGWRVGFIFAQKALIDELIKVHQYLVTAATTMSQK
                     AAAEALINGVKDSENMKEQYQTRRDYLVQQLAPLGFEVTQPNGAFYLFCKLPAAIQTD
                     SWQFCVELAEQAKVACIPGIAFGPEGEGYIRISYASSMEKLHEACKRIKDFLTEQ"
     gene            11538..12917
                     /locus_tag="LLC22_002318"
     CDS             11538..12917
                     /locus_tag="LLC22_002318"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5435571.1"
                     /translation="MEKIKVVIVGASHGGHQSILELLTRYGENVDITLFEAGDYISFM
                     SCGMELYLEDKVTDVNDVRNFRPENFPQSNVHILNNHEVKTIDADKKTVTVTSASDNE
                     TKEYPYDKLILSSGVKPNNLPVPGADLENVYLMRGYNWATKIKEKLNDPAIKKIAVVG
                     AGYIGIEAAEASRKAGKEVVLLDVIDRPLGTYLDAEMTDILEQHLNENGIEVLTNAKI
                     EAFTGNGKVEAIKTSEKEIPADLVIQAAGVKANTEWLKGIVDLDERGWIQTNEYLQTN
                     LPDVYAVGDATLAYSIPARKKMPIALATVARREARYVVKHLFEEVPNKPFGGVVGSSA
                     LSVFDYHFAASGLNSFTAAKAGVDVRVSYYEDTLRPKYVPEEQGNPKVSIQLFSDPMT
                     HQLLGGAVLSTYDVTGQGNVLALAIQNKLTLEELAEADFFFQPGFDRQWSMLNLAAQQ
                     ALGEEPFVE"
     gene            13198..13427
                     /locus_tag="LLC22_002319"
                     /pseudo
     CDS             13198..13427
                     /locus_tag="LLC22_002319"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         4483 a         2339 c         2923 g         3682 t
ORIGIN      
        1 gtaaatgttt tttgataaat agcggtctgc tgcgtctgga aaaatcgtaa cgacacgatg
       61 accaggtggt aaacgacgaa tttctcttaa tgctgctgca aaagccgcac cactcgaact
      121 tccaactaat agtccttgtt ctcgtgctaa ctgcctagta tagttaaacc cttctacatc
      181 agagattgtc tcgatctgat tgattgaaag gggagaaaga aacggcggaa tgaattctac
      241 accgataccc tcaatttcgt gaggggctgg atcaccacca tttaacacag agccctctgg
      301 ttctacaccg attattcgaa tgtcgggata tttttctttc aaaaaggtag aagttccagc
      361 aaaggttcca ccactcccaa ttcctgctac aaaactatgg atattttctt tgatttcatg
      421 aaagatttct ggccctaacg tatgatagta agcagcagga ttatctttat tttcaaattg
      481 aagaggcaga tagctgtttg atatctcctc tgcaagtttt ttacttttgc tgatggcacc
      541 gatgattcct tgctcactag gagaatggat gatctttgct cccaatgctt tcatcaattg
      601 ttgtttttct aagctaaact tctctggaac aacaaaaacc gttcttaatt tgtatgtgag
      661 tgcggccaga gcgatcccaa ttcctgtatt tccggcagtt ggttcgatga tcgtcgtttt
      721 ttcattgatt tttccttggg caaatccttc tttgatcaaa taactgccca atctatcttt
      781 gatacttcct ccaggattta aatattctag ttttgcataa atagcagaac ctttaggcat
      841 agaatagtgc tgattgtcaa agcgataaag cggtgtggaa ccaatagctt ctgtaattgt
      901 cgagataatc atgtgggcct cctaaaaaaa gataataaaa aaaggagctg actattaaat
      961 cagctccttg aaagacatag agaaaaattg agtagataaa aagataagtt acctggtact
     1021 cattctatga agggcaatta atagacatga caaatagtat gctgctttta tgcaccatac
     1081 aacagcaacg attcaattgt ttttggttgc tgactgtcat gtgtatccct ccaagtaaaa
     1141 tttttattaa cgatagcatg aaaaaaaata aaagtcaaag gcttgaaaga aaaaaatatt
     1201 tcgatagcat cgtttacccg tgtttatttt tctgacaaat aggcatgaga ccttaaaaga
     1261 tagagaatac tctagttttc tggccggttg tctgatacaa taaagttgat tatgataaag
     1321 aaaagaagga gcaaaaataa tgatctcagc aagtgattta agagccggta tgactttcgt
     1381 acaagacggc aaactgatta aagttctgga tgcaagccac cataaacctg gtaaaggaaa
     1441 tacagttatg cgtatgaaac tgaaagatgt ccgttcaggt gcaacatacg acacaacgtt
     1501 cagaccagaa gaaaaatttg aaaaagcaca tatcgacaca aaacctgtac aatatttgta
     1561 cacgatggat gatacagctt tcttcatgga tttggaaaca tatgagcaat atgaaattcc
     1621 tgtagaaaca gtagaagaag aaatgaaata tatcctagaa aacatggaag taaaaatcca
     1681 atttttcggt agcgaagtca tcggcgttca attaccaaca actgtcgtat tacgtgttgt
     1741 ggaaacacaa ccttccatca aaggtgcaac agtcactggt tcaggtaagc cagcgacaat
     1801 ggaaactggc ttagtagtca atgttcctga cttcatcgaa acagatgaat tgttggaaat
     1861 caatacagca gaaggttctt atgtaaaacg tgcgtcaaaa taattcgcta acggattgat
     1921 aagaatttga aaacagagct tgacctcttg aaaggcagat catcggatct gcctttcaag
     1981 aggttttttg tggaatcagc aaattgaaaa ataaaaaagt atttgatttt atttatattt
     2041 tgaaagatga atggcaaaag ctagagaaag aaaaaactgc acttatttat gaagaaattg
     2101 aaatgattca taaaattgaa aatatccgaa ctattccgaa ctatattgaa gcgaaaatat
     2161 tttttcatca ctaaatagtg ttgaatttat gtttttatgt ataaatagct tctaatagtt
     2221 cgggtatttt gtttttataa ccatttttat tcttattttt aaaaaaatat ttcgaaatat
     2281 actagacaat tcagaaaatt ttgtttaata ttattccaat aaaattcaaa tctttatcaa
     2341 atgaaattcc aataaaaacg gaaaaaaagt gaaaagagga atgaaaaaat gacagaattg
     2401 ataattggcg gagtcacagc aagcacattg gcagaaaagt ataagacacc tctgtatgtg
     2461 tatgatgaag aaaagatgag acaaacgatg ctgtcattca agcgaggctt tgtatcgaaa
     2521 cgttttgata caaaagtgct ttacgcctct aaagcattcc aaacgattga gatgctgcat
     2581 ttagttcgtg aatatggatt cgggctagat gttgtcagtg gtggggaaat ctataccgct
     2641 ttgcaagctg attttcctag agatactatc tacttccatg gtaacaacaa gacgccagag
     2701 gaactgatct atgcacttga aaatgatttg ttgcatattg ttgccgataa tttgatggaa
     2761 gttgaattat tagcagaatt aagccaacgc tatttaaaaa aaatctgtat catgcttcgg
     2821 ttgaatgtcg gagtagaagc acatactcat gaatatatcg tcactgcgca tattgattca
     2881 aaattcggca tgagctatga aagtaaagag tgccaacaag cccttcagtt gataaaagaa
     2941 agcagctatc tagagttaga aggatttcat gctcatatcg ggtcacaaat ttttgatgtt
     3001 actgcttggt tagctgaaat cgacaaattg acgaattact taaccgattt tgaccaacct
     3061 ctttccttga atcttggcgg agggtttggg attcgttata cacaaaatga tcagccgatc
     3121 ccagtcgaag aggcactaaa aaaactgatt gaatatacgg aagaagcttt ggaaaaacga
     3181 aaactgacca ttcgtcaatt actgatcgaa ccgggtagaa gtattgttgg agaagctggt
     3241 acaacactat acacgattgg tttcatcaaa aagacaccac ataaaaaata ttactttgta
     3301 gatggcggga tgacagataa tatccgtcca gctctgtatc aggcagaata cgattgtgat
     3361 ttagcagcaa aactgtcgga agaaaaaaca gagaaagtga cgattgcagg aaaaatgtgt
     3421 gaatcaggcg atgtggtaat taaagaagct tatttgccga aagcagaatc gggtgatctt
     3481 ttagctgttt attccacggg agcttatgga tactcgatga gcagcaacta caatcgagcg
     3541 acacgaccag cagttgtttt tgtcaataat ggccaatcaa gactgattgt tcgcagacaa
     3601 gcattttctg atctactaag gggggaagtt tcctatgatc cttcataaat ataatggctg
     3661 cggaaatgat tttatcttat tagattacgc agaagacaca gattatagtc aattagccgc
     3721 ttctttatgc acaaaagaaa aatatgatat agacggattg atcgccgtaa aaatcgatcc
     3781 gttggaaatg atctattaca acaaagatgg cagccgcgcg ccgatgtgcg gaaatggcat
     3841 tcgctgtttt gctcgatacg taaatgatca gaacatgatg aatgaacagg aattcaacgt
     3901 agagacatta gcaggcacaa gaaaaattac ggtgttggat ccctcacctt tttattgcag
     3961 cgtagatatg ggagtgccag atgattctcc ggaaaaaatc aaagctaatc aaacttatcc
     4021 aataaaaaac caggaaatag agatcaatgg tgaaaaagta acgatcacta gtttattttt
     4081 aggaacgatt cataccgttg tttttgttga aaatgcgcgt gaggaagtct ggagaaaaag
     4141 aggtgaactg atctgtcatc atcctttgtt caaagaaaaa accaatgtca actttgtaga
     4201 agtagtcaat gaacaagaat tgatcgtccg tacctatgaa agaggagtag gttggacact
     4261 tgcttgcggt acaggttgct gtgcctctta tgtggttgct aaggaaactg ggaaaatttc
     4321 agcagatcag gtagttgttc acttggaaca aggagacttg atgatctctg gtgaggatgc
     4381 gatacaaatg gctggcccag cagttcatga atggacaaga atattggagg aatgaagatg
     4441 ataaaaggtt cgatcgtggc gctgatcacg ccgatgaatg aagagggatc agtagattat
     4501 gctggtttgg aaaaattgat ccaattccat ttagatgaac aaacagatgg attattagtt
     4561 ttaggtacaa caggagaatc ttctacgctc acacaatctg aggaggagca gatccttcaa
     4621 ctgacagtaa agaaagtggc tggccgtgtg ccggtgattg caggagctgg aacgaataat
     4681 acgaaagaaa cgattgaaaa agcgaagcat tttgcttctt tgggggcaga cgcacttttg
     4741 gtcatcaccc cttactacaa caaaacaagt gatgcaggac tagctgctca ttttacagca
     4801 attgcagaag cctcaccgat tccgcttatt ttgtataatg ttccttctag aacaggcatg
     4861 tcgattccaa tccatgtatt agtaaattta gcagaacatc ctaatatcat tggtttgaaa
     4921 gaagcctcag gagatatggc ttatgtgatg gatgccgctc ggttgattgg agaagaattc
     4981 ttcctttaca gtggaaatga tgatttgatc ctaccagtaa tgagtgtagg aggaagcggt
     5041 gtaataagtg tatgggcgaa tatccaacct aaaatagtcc atgaattagt aaaagatacg
     5101 caggacggaa gatggcagca agcaaaagaa aagcaattaa atgcacttga actgatccat
     5161 gccttgttca gtgagaccaa tcctattcct gtcaaagcag ccatgtcatt attagactta
     5221 ccttccggac ctctacgcct gcctttagtt tctctttcaa aagagaaaaa gaaacaatta
     5281 gctcagcttt tgttaaaaga aaggacggtt gaaaaatgaa aatcggactg attggcagtg
     5341 gacagatggg aaatagagtc gaagaagttg cacaagaaag aggagatacg gtccttcttt
     5401 tacggacggc acctaaagaa gcaactacgc ttgcttttac ggaactgcca gaactgctta
     5461 ttgatttttc tcatccagat aatttagaga aaatcctttc gtatagctta tcatatcaac
     5521 ttccgttagt cattggcacg acaggttata cacaatcaca gttccaagaa ataaaagaac
     5581 atgccaaaca tgtacctgtg atgtatagtg ctaatttttc gttcggcatc atggtgatga
     5641 atcaactaat caagcaagca gctgcaatgt tgcaaggctg gcagatcgaa ctgattgaaa
     5701 aacatcatag tcgtaaaaaa gatgcaccat ctggtactgc aaatatgctg cttcaaacaa
     5761 tccaagaagt gcaaaagctg cagcccgtat acaactggca agggaaaaaa agagaagaaa
     5821 accaaattgg tgtacacagt attcgtgcag gttctttacc tggtgaacat gatgtattgt
     5881 ttgctgctac tgatgaaata tttacgatca aacatgaatc tttttctaat cgaatctttg
     5941 ctgcaggcgc agtagaagca gcggactggt tgaaagatca gtcaccaggt tattacaaat
     6001 tagaagattt attaatggac aaaggggtgt aaaaaacgtg gaagctcaag aaatcatccg
     6061 ctacattcaa acggcatcta aaaagacgcc tgtgaaagtc tatctgaatg taaccgagcc
     6121 aatcgaattt aaagaaagta aagtttttgg tgaaggaagc agcttcgttg tttttggtga
     6181 ctatgagacg attgctccgg ttttagaagc tgaatcagaa aaaatcattg aaatcgaaat
     6241 cgaaactgct gcaagataca gcgcagttcc tttgctagat attaaaaaaa ttaatgctcg
     6301 tatcgaacca ggtgctatta tcagagatca agtgtcaatc ggcaacaatg ccgtgatcat
     6361 gatgggagcg attatcaata ttggtgcagt aatcggtgaa aacacgatga ttgatatggg
     6421 tgctgtctta ggtggacgag cgacagtggg caaaaactgc catattggtg caggagctgt
     6481 cttagcaggt gtgatcgaac cagcatcggc caaaccggtt atcgtagaag acggcgtact
     6541 ggtaggtgcg aatgcagtga ttgttgaagg tgtccatatc ggaaaagatg cagtcgtggc
     6601 agcaggagca gtggttttag aagatgtggc agcagaaact gttgtcggtg gaatacctgc
     6661 acgtgtatta aaaataagtg atgatcagac aaaagaaaat acagcattga ttgctgcgtt
     6721 acgcgaatta tagaggagat ggagaaaaat gcgcgaaata gatacctgta ttgtgggggc
     6781 aaccggatta gtcggccaaa cgatgctcaa agtgttagaa gaatatgatt ttccagtagg
     6841 acgattgaaa ttattagctt caaaacgttc agccggtaaa gtttgtgtat tcaagaaaaa
     6901 gaaacacact gtacaggaat tgacagaaac ttcatttgaa ggatatgatt tagcgctatt
     6961 ttctgcaggt gcttctgtat ccaaagagtt tgcgccaatc gcacgaagtc agggactatt
     7021 tgtcatagat aattcctcag catggcggga agattcggat attccattaa tcgttccaga
     7081 ggtcaatctg gaagactata cattgaatcg gctgattgca aatccaaatt gttcaaccat
     7141 tcaagcggta cttccgctta aagctttaca agaagccttt ggtatccagc gagtcaatta
     7201 ttcgacctat caagcagttt ctggttccgg gcaaaaaggc attgaagatc ttcatcgtac
     7261 gcaaaatgac gagaaaccag ttttgtatcc ttataatatt agccaaacgg tgattccgga
     7321 aatcgatcag cctttggaaa atgggtatac aaaagaagaa cagaaaatga taaatgagac
     7381 ccgtaagatt ctgcatcagc ctgctttgcc agtatcagca acctgcgtac gtgtgccaat
     7441 cgaaaatgga catggagtct ctgtggcagt tcaactgcaa aaagagttta cgacggaaga
     7501 aattagagag tgtctcagcc agtttccagg gattcaatta gaagatgatc tagcagcaca
     7561 taaatatccg acgagcattc ttgctagagg aacagatatg gtttatgttg ggaggatcag
     7621 aaaagacact tctttagaga acggattgtt gttctatacg actgccgata acatacgcaa
     7681 aggagccgct gcgaatgccg tacagattgc tgcagcttta atgcagaaaa tagcggaggt
     7741 ggcaagatga gtaatacgct gaaagtagcg aaattcggcg gaacatcgat gtctcatgaa
     7801 gagcaattca aaaaagtccg tacaattgtt ctttcagatc ccaatcgcca agtgatcgtt
     7861 gtttctgctt taggcaaacg tacgtcagat gatgacaaag taacagactt actttatttg
     7921 atttatgctt accttcagca tcatgttgat tggacacccc tttggaaaag gatttgtgat
     7981 cgtttcattc aagtaagaga tgttcttgcc ctgcagttac ctattgaaga tgaactagca
     8041 cgcatacaga aacaactgga agacgaaaag ataactgaag attatttagt aagtagaggt
     8101 gaatatctga ctgctcaact gatggctgag tatcttggtt accagtttat tgacgcaaaa
     8161 gacctgattt tctttgacta tgatgggaaa atcgatcagg aaaaaacagc acaggaaatc
     8221 acaaaagcat ttaaaagata tccgaaaatg gttgttccag ggttttacgg ggcgaaccct
     8281 gcaggaaaag aaaaattatt gggccgtggg ggaagcgaca ttaccggcgc gatactggcg
     8341 aagatgttgc aagcggaaag ttatgagaat tggacggatg tttcaggaat catgatggct
     8401 gatccgcgaa tcatcgatca tcctaaaatc atcgaggaaa tctcttttag agaactgaga
     8461 gagatggctt atatgggggc taacgttctt catgaagcag ctgttttccc agttcaagag
     8521 gctgatatcc ccatccaaat aaaaaatacc aatgatcctt tcgctcaagg gacaaaaata
     8581 tcgaatcacg aaatagaaaa ggaaaatgga ctgacaggaa tagctggacg caaggatttt
     8641 ctttccatca ctttattcaa acgtcatatg tccgatgaaa tcgggtttat ctggaaagca
     8701 atgagcattt ttgctaaaca tgagatatca atcgaacata ttccttcagg gatcgacaat
     8761 atcggagtga tcgtctcagc agaagcgatt gccgataagt tatttctcat cacgaaagaa
     8821 ttaaaagaaa cacttggcgt ggaagaaatc gtcgtgatcg aagacttagc tttgatctct
     8881 gtcgttgggg gtccgcataa agaattgatt ggattatctg ggaaagtgtt atcgatattg
     8941 aacaaattag aaattcgcac atcgatctta tcacaaggag cacaggagtt gaatctgatc
     9001 atcggtgtac cgaataatca atatgaaaca gtagtgaagg gtatctatga agggatggtg
     9061 aatacggatg ctgaaagaat atcgaatggc actccatcaa attcctgaaa tcgggtttca
     9121 tgaattcaag acaaaaaaat atttatatga acaagtaaaa aacagcgagg ccgttatcca
     9181 tgaaatcggc gaaacaggac tactccttta ttttgataat cagcaagaag aaacgattgc
     9241 ttttcgaaca gatatcgatg cactgccagt caaagaagaa acgaatctct cttttgcttc
     9301 taagcatgaa ggttatatgc atgcatgtgg tcatgacgga catatggcga tgcttttagg
     9361 gttgactgac tttataacta aacacattga ggatcttatt tataatgtag tactgatcta
     9421 tcagccatca gaagaaattt ccggtggcgc acaaagcgtt attcagtcag gattgttgga
     9481 taaatatgaa gtacaagcaa tatttggctt tcatctatgg cctggactag ctaagggaga
     9541 agttttctct cgaccaggac ctttgatggc acaaagcagt gaaacagaca ttatcattaa
     9601 aggccagtct gcacatattg cttctagtga aaaaggaatc gatagtctgg aggcagctgt
     9661 acgatttttg aagaatgttt atgattttga ccggcaatta ccggcagagt ggaatcatct
     9721 aatgaaattt ggccaaatcc aaggtggaac gatccgaaat gttttagctg gagaagttat
     9781 tgtatccgga agtatccgtt cttacagttc agatatgcaa aattatttga agaggggatt
     9841 agaccattta gcagaacagt ttcactctac agctactatt tcttttcgct ataatgacgg
     9901 ctatccagct gtaatcaacc atagaggctt atatgcagca ctgttagatt caaacaaact
     9961 acatgaatta gatgctccag ttcttcaagc cgaagatttt ggcatatata cgcaacaata
    10021 tccatgtgta tttttctttt taggtgtcgg tgatacccct gctttacatg atccgacgtt
    10081 cgattttgat atggatgttt tagaaaatgg tgtagaatgg tacaaaacga ttctttttac
    10141 agaaaatctt cttgtaaaaa tcgatagcag ttcaaaagag gagcgagtaa ataatgatga
    10201 atttatccaa tcgatttagt cctaggcttt ctagaataga agtatcaaaa atacgacaat
    10261 tcgatcagca aatatcgtcg ataccagatg tgatcaaact caccctggga gaaccggatt
    10321 ttccaactcc tgaacatgtc aagcaagcag gaatagcagc gattgaagaa gacttttctc
    10381 actataccgg aatgagagga ttagaggaac tgcgggaagc ggcttgtata tttcagcaac
    10441 agcgttatgg attaacttat gatccgcaaa cggaagtttt gacgacagtt ggtgcaacgg
    10501 aagcgattgc ctctgcgttg ttatctgttt tggaagaagg agacaaggtt cttattccag
    10561 cgcctgctta ttcaggatat cagccattag tggaactagc tggtgctgaa ttgatcccga
    10621 tagatacttc tgacacaggg tttgtctgtc agccggaaca atttgaacga gcatttgaac
    10681 aatatggatc agctgtcaaa gcagtcattt taaactatcc taacaatcct actgggacga
    10741 cattgtctgc aaaacaattg aaagcaatcg ctgaggtttt aaaaaaatat ccggtatttg
    10801 ttataagtga tgaagtatat gctgaattga cttatagtgg aacgcatatg tccatagcta
    10861 cttatcttcc agaacaaaca atcgtgataa gcgggttatc caagtcacat gcgatgactg
    10921 gttggcgagt gggctttatt tttgctcaaa aagcccttat tgacgaacta attaaagtcc
    10981 atcaatatct ggtgactgcc gctacaacga tgtcgcaaaa agctgcggct gaagcgctaa
    11041 taaatggggt gaaagatagc gagaatatga aagagcaata tcaaacacga agagactatc
    11101 tggtccagca attggcgcct ttaggatttg aagtgaccca gccaaacggt gcattttact
    11161 tgttttgcaa actcccagct gccattcaaa ctgactcttg gcagttttgt gtagaattag
    11221 cggaacaggc aaaagttgcg tgtatcccag gaattgcatt tggcccagaa ggagaaggtt
    11281 atatccggat ttcttatgct agcagcatgg aaaaattaca tgaggcctgc aaacggatca
    11341 aagacttttt aacagaacag tgattcatag attttatcaa aaaaacaatc gttaattttg
    11401 cggtatattc tgcaaggaga cgattgtttt ttaaatttag ttcaaatgaa cgcgtttctt
    11461 ttgattcata actaatgtaa tgttaagttt aaattgttta gaatgatttt aaaagaatat
    11521 tcaaggaggt ttcatcaatg gaaaaaatca aagttgtcat tgtaggtgca tctcatggag
    11581 ggcatcaatc gatcttggaa ctattgacac gatacggtga aaatgtagat atcacgctat
    11641 ttgaagcagg agactatatt tccttcatgt catgtggtat ggagctgtat ttagaagaca
    11701 aggtaacaga tgtaaatgat gtacgtaatt tcagaccaga aaactttccg caatccaatg
    11761 ttcatatttt aaataatcac gaagtaaaaa cgatcgatgc cgataaaaaa acagtaacgg
    11821 ttactagcgc atcagataac gaaacaaaag aatatcctta tgacaaattg attttgagtt
    11881 ctggtgtcaa accaaacaat ctgccagtac caggagcaga tctagaaaat gtctacttga
    11941 tgcgtggata caattgggca accaaaatca aagaaaaatt aaatgatccg gctattaaaa
    12001 aaatcgctgt cgtaggtgcg ggttacattg ggatcgaagc agcagaagca agccgaaaag
    12061 ctgggaaaga agtcgtattg cttgatgtga tcgatagacc tttaggcact tatttagatg
    12121 ctgagatgac agatatttta gaacaacacc taaatgaaaa cggtattgaa gttttgacaa
    12181 atgcaaaaat cgaagctttt actggtaacg gaaaagttga ggcaatcaaa acaagtgaaa
    12241 aagaaatccc agcagatcta gtcattcaag ctgccggtgt gaaggcaaat acagaatggt
    12301 taaaagggat cgtcgactta gatgaacgtg gctggatcca aacaaatgaa tacttgcaaa
    12361 cgaatcttcc agatgtgtat gcagtaggag atgctacact tgcttattct atcccagcac
    12421 gcaaaaaaat gccgatcgct ttagcgactg ttgcacgtag agaagcacgt tatgtagtaa
    12481 aacatctttt tgaagaagta ccaaacaaac cgttcggcgg agtcgtaggt tcctctgcat
    12541 taagtgtctt tgactatcat tttgcagcaa gcggattgaa tagctttaca gcagcaaaag
    12601 caggagtaga tgtacgagtg tcttattatg aagatacgtt acgaccaaaa tatgtaccag
    12661 aagaacaagg aaatccaaaa gtgtccatcc aattattctc ggatccaatg acccatcaat
    12721 tgctaggagg agcagtatta tctacctatg atgttacagg tcaaggaaat gtattggcac
    12781 tagcgatcca aaacaaactg actttagaag aactagcaga agctgacttc ttcttccagc
    12841 caggctttga ccgacaatgg agcatgttga atctagccgc tcaacaagcg ttaggagaag
    12901 aaccatttgt agaataagaa aacgaaatat ttgaaaagag gttgtgaaaa agctgccttg
    12961 catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttaac ttggctggac
    13021 ttattaccgc agatgcaagc ttttgaacac cgtttatttt caaaaaaggg actgtgacac
    13081 gatttgtgta ccgaccccca aaagttagac caaaaaatct aacttttgga ggtcggtatt
    13141 ttttatggtt aaatatactt ttgaacttaa attaaagatc gttcatgatt atttggatgg
    13201 caaaggcgat tggaccgtaa aaatccagat caagagattg aagcggaaat gcttaaaatt
    13261 cgggagaagc acaaggatta tggctgttta cggatgacca atgaactaag aaaccgcggt
    13321 ttctctatca ataaaaagaa agttcagcgc ttgatcaaga agctaggaat aaaagtaacg
    13381 gcatacacgc gtaaatcacg tcgctacaat tcttatcgag gaaaagt
//
LOCUS       DAFBVQ010000069        13404 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.072, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000069 DAFBVQ010000000
VERSION     DAFBVQ010000069.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13404)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13404)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13404
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.072"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            79..1125
                     /locus_tag="LLC22_002320"
     CDS             79..1125
                     /locus_tag="LLC22_002320"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349488.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan DD-metalloendopeptidase family
                     protein"
                     /protein_id="HBK5435572.1"
                     /translation="MTKPNHIESSKKEAPKTEGQTKTFSTPQQIESTESFQSQPILSG
                     NEEIHFDKNESVENFIMKIGESARKIGQKYDLYASVMIAQAILESASGQSQLAQAPNY
                     NLFGIKGTYNGNFVIMVTNEDLGNGTLYTTQSKFRVYENYEESFEDYAKLLTKGISGN
                     KDFYAGALKANSKTYREATKFLTGRYATDTQYYLKLNELIKTYDLTNYDKEVKGPQMS
                     KTGYQVPIHNYSITSLFGNRGNEFHRGLDMAATQGEPIHAVKAGKVVKAEFHYSWGNY
                     VVIQHEDGSTALYAHQQQYLVKTGDNVLQGQIIGYVGSTGNSTGPHLHLEICKDSSLS
                     QSMLVDPKTLLFGD"
     gene            1474..2106
                     /locus_tag="LLC22_002321"
     CDS             1474..2106
                     /locus_tag="LLC22_002321"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AP2 domain-containing protein"
                     /protein_id="HBK5435573.1"
                     /translation="MKERYGHLTVVEEITHNGYKKYRCLCDCGNETIVYRSNLLSGRT
                     KSCGCGNYKNRHKYKNLTNKTFGKLVAIKPTKLRSEGTVVWECQCLCGRKKLVSAKRL
                     LKGDVKSCGCLKSKKHHIENKKFGLLTAKYPLDNNCSWKTKWVCHCECGSMCEISYSN
                     LFFGHTQSCGCLKRQETRTCVEGTVIECLTSKLPKNNTSGVKGVYRSKEK"
     gene            2694..4133
                     /locus_tag="LLC22_002322"
     CDS             2694..4133
                     /locus_tag="LLC22_002322"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297342.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5435574.1"
                     /translation="MYSYQEDAKVQKNRWWILIAISMFTFMSTLDGSIVNIALPTISD
                     DMGIPMNQAEWVVSVYLMIVCSCLLLFGKIGDSRGKIKVFRIGTLIFVLGSLLCGFNH
                     SLGILLFARVVQAIGASMTMATNAGIITEVFPIHERGRALGAIGAFVSLGSIAGPGLG
                     GLILSQFSWAYIFWINVPVGIVTMLIAEKFLPKDITMSGHTIDGGGFAAIAATIISFF
                     GAIFLGQESGFFHPVPLVLFVISVIAFVSFLKVEKKAASPLISFGIFKNKIFTMSLIT
                     ALLIFSSNFFVNVVIPFYLQNARGLSPSYAGLLMMVFPLMMVVGAPLSGYLTDRVGPE
                     ILVLVGLGLLSVTQVMYMFLSVDSPLWLYIVATAIMGAGNALFQSPNNTMVMSSVTIE
                     NLGLAGSMNSFARNLGMVSGISLSTTVLYQAMSAKMGQQVTNYIANRPDVFLYGMKIT
                     FLGSFVLCFVAFFLTIWRIKKQGGIQKNV"
     gene            4428..4646
                     /locus_tag="LLC22_002323"
                     /pseudo
     CDS             4428..4646
                     /locus_tag="LLC22_002323"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016251366.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            4895..5110
                     /locus_tag="LLC22_002324"
     CDS             4895..5110
                     /locus_tag="LLC22_002324"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297343.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435575.1"
                     /translation="MNAGIADMNLIKKTLNDFTSNSISKGTGINLSTIKKLKSGERSV
                     EKLNLLDAIKITEFAMKNGKAEIEIWR"
     gene            complement(5327..5583)
                     /locus_tag="LLC22_002325"
                     /pseudo
     CDS             complement(5327..5583)
                     /locus_tag="LLC22_002325"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="frameshifted; internal stop; incomplete; partial in
                     the middle of a contig; missing C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
     gene            complement(5770..6681)
                     /locus_tag="LLC22_002326"
     CDS             complement(5770..6681)
                     /locus_tag="LLC22_002326"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5435576.1"
                     /translation="MKIKIERNQKEKSPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GVYKNFTAIDQHTTHEKVVIKEKVVNTSGVESFTEDFAKEYFSWKNNKEAIEKRMSNL
                     EQYLTENGLALIQDMVRADIPTSSEVQSVKILDVEKHSEEFVVSFLVEQHITEGKKTQ
                     SISSAYRVTIFEDENRNHLVTSLPTMIGKPDKAKYEAKQVENDSEIDAKTTEEITDFL
                     ETFFKLYPSASEKELEYYVENGAMRPINIDLKFSELENPVYLQNGKNFLVSTKIKYLD
                     NVSKTTSYFQYKLVLQKNGNWKIVDVK"
     gene            complement(6700..7704)
                     /locus_tag="LLC22_002327"
     CDS             complement(6700..7704)
                     /locus_tag="LLC22_002327"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346909.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK5435577.1"
                     /translation="MNLKKVGVISLTFLTISFMGILMCVGLLFGEDSEGNGSSGTSPG
                     GTSVSEEVLKHRAMVEKYAKESDITEYIPILLAIIQVESGGTMEDVMQSSESAGLPPN
                     SLSTEASIKQGCLYFASLVKRSKELGCDQDSIIQAYNYGGGYLDHVGKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENGGWRYNYGNMFYCLLVKQYLTTTQFDDKIVQEIF
                     DEAFKYEGTAYVFGGSSPETGFDCSGLTQWCYAKVDLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLVFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTENYWRQHLIGAGRYK
                     "
     gene            complement(7701..9824)
                     /locus_tag="LLC22_002328"
     CDS             complement(7701..9824)
                     /locus_tag="LLC22_002328"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5435578.1"
                     /translation="MKKKLFRIVGIVFISILTLIVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAESIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRAVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALTLGTEIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEDRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKKAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRALAFGGGAAVGNKLAKEQSKSKFKPSGSSLRKNSRLPNDHEILSDLTKEN
                     PVSNNKKQSRMNLAGRKIGKVLDTQALVKDKTKQVKDQVRNTPTNLKYNLHKGIEKSK
                     KAPEEFKRGLFQEKADRVDLREKQRQRRNAKMDEKRKILSEATNRQGKRRANIPIDKA
                     AQPQKDMMLKKEAPKRIVRANLNPEIKRKLTSQEIISKGKSQSASKKNSFQQVKQRST
                     LPKQTNQKVQKRMNHRPKSRSGEKK"
     gene            complement(9829..12276)
                     /locus_tag="LLC22_002329"
     CDS             complement(9829..12276)
                     /locus_tag="LLC22_002329"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5435579.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELIPYNYSFLSPEQKYQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLTEVAKQRIDLQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKNLKKSFFSGFQEFVYGVNHHLMGDFVSLSNEEI
                     RRYTKLEKLMESKLARRFKVRRVTPSDLMYLIEHIYGEKGTPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPSRCLIEEKPRYLCMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEINILNLTSKPKNQGLLDPYVIMEKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSNQRGLLQVINELRKEGSPVAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDRQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDREDESNQKRLRDLENGQCLMQDLYGRVGVVQVHPVFE
                     ELFHAFDTRPPVQERME"
     gene            complement(12263..12652)
                     /locus_tag="LLC22_002330"
     CDS             complement(12263..12652)
                     /locus_tag="LLC22_002330"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5435580.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEGAFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPITLVRSVNYVPD"
     gene            complement(12712..13215)
                     /locus_tag="LLC22_002331"
     CDS             complement(12712..13215)
                     /locus_tag="LLC22_002331"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010718210.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK5435581.1"
                     /translation="MEQMRVYIANLGKYNEGELVGAWFTPPVDFDEVKERIGLNDEYE
                     EYAIHDYELPFEIDEYTPIEEINRLCGLAEELEGTPVGEVASEIQHAFFNSFEEMVEH
                     VDDIIYYPDCDDMSDVAYFLIVEAGDFGEVPEHLKTYIDFDACGRDLEIGGNYLVTSR
                     GVFEYPY"
     gene            complement(13228..13389)
                     /locus_tag="LLC22_002332"
     CDS             complement(13228..13389)
                     /locus_tag="LLC22_002332"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435582.1"
                     /translation="MAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGVKDVLL
                     SLFNRIVGA"
BASE COUNT         4099 a         2643 c         2454 g         4208 t
ORIGIN      
        1 tcaagtgaaa gtagtacgat ttcaagtacc gaatcttcaa caacttcaag tagtacaagt
       61 gaaataactt cttcgaaagt gacaaaacca aaccatatag aatcttcaaa aaaggaagcg
      121 ccaaaaacgg aaggacaaac aaaaactttt tcgacaccac agcaaataga atcaacagaa
      181 tctttccaat cacaaccaat actatctggt aatgaagaaa ttcattttga caaaaatgaa
      241 tctgtagaaa attttattat gaaaattggt gagtctgcga gaaaaattgg tcagaaatat
      301 gatttatatg cttctgttat gattgcacaa gcgatcttag aatctgccag tggtcaaagc
      361 cagttagctc aggcaccgaa ttacaattta tttgggataa aaggaactta taatggaaac
      421 tttgtcatta tggtaacaaa cgaagatttg ggtaatggaa cgctttatac gacccaatca
      481 aaatttagag tgtatgaaaa ctatgaggaa agctttgaag attatgccaa attattaact
      541 aagggaatta gtggaaataa agatttttat gcaggagcat taaaagctaa tagtaaaaca
      601 tatcgagaag caactaaatt ccttacagga cggtatgcaa cagatacaca atactatttg
      661 aagctaaatg aattaattaa aacctacgat ttaaccaact atgataaaga agttaaaggt
      721 ccacaaatga gtaagactgg ataccaagtg cctattcata attattcaat aaccagtttg
      781 tttggaaatc gtggaaatga atttcaccga ggacttgata tggcagctac acagggtgag
      841 ccgattcatg cagttaaagc tggtaaggtt gttaaagcag agtttcacta ctcttgggga
      901 aattacgtgg tgatacaaca cgaagatgga tcaaccgcgt tatatgctca ccagcaacaa
      961 tacctagtaa aaactggaga taatgttttg caaggacaaa taattggcta tgtaggaagt
     1021 actgggaata gtactggccc acaccttcat ttggaaattt gcaaagatag tagtctttct
     1081 cagagcatgt tagttgatcc gaaaacctta ttattcggag actaaaaaag gtaatcaatc
     1141 tgacaaagta acaagaaaat ggttggattc ttagaccttt gatcaggata ttgagactgg
     1201 aattgatatc tcgattacga tgggtttgac aaataaaaca agtccattat cgaatatcga
     1261 gtgtattatt gccgtcttta tgctcatatt ttgagcaggt ttcactagat gaaaacaatt
     1321 tatctatctt gaggatttcg tgtacgtatc gttcagtctt gtattgtaaa ttagtcataa
     1381 aatcagacta agaaaaattg gaaatatttt tttctgattt attaaaagtt aattgaaatt
     1441 atatggtact tctttcttgg gagggtaggt gcagtgaagg aaagatatgg tcaccttact
     1501 gttgttgagg agattactca taatggatat aaaaaatatc gttgcctatg tgactgtggg
     1561 aatgaaacga ttgtatatcg atcaaactta ctatcaggta gaaccaaaag ttgtggatgt
     1621 ggaaattata aaaataggca taaatataaa aatttgacaa ataaaacttt tggtaagtta
     1681 gttgcaatca agccaactaa actgcgaagt gaaggaactg ttgtttggga atgtcaatgt
     1741 ctgtgtggga gaaaaaagtt agtatcggca aagcgacttc taaaaggtga tgtaaaaagc
     1801 tgtggatgtt tgaaatcaaa aaagcatcac attgaaaata aaaaattcgg attacttact
     1861 gcaaagtatc ctttggacaa taactgttca tggaaaacaa aatgggtttg tcattgtgag
     1921 tgtggcagta tgtgtgagat aagttatagt aacttatttt ttggacatac tcaaagttgt
     1981 ggatgtttaa aaaggcaaga aacaaggaca tgtgttgaag ggacagtaat agagtgtcta
     2041 acgtcaaaat taccgaaaaa taatacaagt ggtgttaagg gagtttatcg ttctaaagag
     2101 aaatagattg cgtatataac tttaaaaaaa aagaggtact atttaggatc gtatgattct
     2161 attaagagtg cagctcaagc tagaaaagat gctgaaaata aattgtttca acctttgatt
     2221 gacaaatatc gaggtaatca ttaattattg tggataataa ttaacagtga tatataaaca
     2281 tctataatat attattcata ctattgatat ttagtataat cctatggaat tgaatatcat
     2341 agcaatgtat ttgaaaagca aattggaaaa caaataggtg caacaccata aatatgaaaa
     2401 aattgggaaa aagtagaatg gaaatttgct tacgtctcac gagatagctc acactattaa
     2461 tctgaagaac aatgaagtcg acttttagaa attgctagaa gaaagtaaag cgaattatca
     2521 ctagttacta tagagtaagt tcaaataaag catctccaac ttacatggtt acatgaggat
     2581 atcaaatcga aattactcaa gcttcctatg gctagagtcg cgagaagttg ttgggcagta
     2641 gacataggtt atattgttct tagctacacg atcattagaa aggaaatcct attatgtata
     2701 gttatcaaga agatgcaaaa gtccaaaaaa atcgctggtg gattttgatt gctatatcta
     2761 tgtttacctt catgtccaca ttggatggca gtattgtcaa tattgcacta cctaccatct
     2821 cagatgatat gggcatacca atgaatcaag cggaatgggt agtgtccgtt tatctgatga
     2881 ttgtctgttc ttgtttgttg ctgtttggta aaattggcga tagccgtggg aaaatcaaag
     2941 tatttcggat tggtacgctg atctttgtct tgggatcgct gttgtgtggg ttcaatcatt
     3001 cgctaggtat tttattgttc gcacgggtgg tacaagccat tggtgctagt atgactatgg
     3061 ctacaaatgc cggaatcatc acggaagtct ttcccataca tgaacgtggt cgggcattgg
     3121 gagcaatagg tgcgtttgtt tcattaggct cgattgctgg accaggtctt ggcggcttga
     3181 ttttgtccca attttcttgg gcgtacattt tttggatcaa tgtaccggtg ggaatcgtaa
     3241 cgatgttgat tgctgaaaaa ttcttaccaa aagatatcac catgagcggc catacaatcg
     3301 atggaggggg ctttgctgcc attgcggcta cgattatcag cttttttgga gcaatctttt
     3361 tggggcaaga aagtggcttt ttccatccag tcccccttgt actgttcgta atttcagtga
     3421 ttgcctttgt cagcttttta aaagttgaaa agaaagcagc ctctccattg atttctttcg
     3481 gtatttttaa gaacaagatt tttaccatga gcttgattac agccttgttg attttttctt
     3541 ccaacttctt tgtcaatgta gtgattcctt tttatctgca aaatgctcgc gggttgagtc
     3601 ctagctatgc tgggctgttg atgatggtct ttcctttgat gatggtcgtc ggggcgcctt
     3661 taagcggcta cctgaccgac cgggttggcc cggagatttt ggtattagta ggcttgggct
     3721 tattgtcggt aacccaggtc atgtatatgt ttttgtcagt ggactctcct ttgtggctat
     3781 acattgtcgc tactgccatc atgggtgccg gcaatgcctt gttccagtcc cccaataata
     3841 cgatggttat gagctcggtc actatcgaaa acttgggact ggcaggctcg atgaattcct
     3901 ttgcccgaaa tttggggatg gtcagcggga tttcgctttc tacgacggtc ttatatcaag
     3961 cgatgtctgc taagatgggc cagcaagtaa ctaactatat cgcaaatcgg ccggatgtct
     4021 ttttatatgg aatgaagatt acctttttag gcagctttgt tttgtgtttt gttgcctttt
     4081 tcctgactat ctggcgtatc aaaaaacaag gaggtattca gaaaaatgtc tgaaaaaacc
     4141 actgttgaag aatttttgga ggcctgcgta tgggtgagtg ggatttccat ggatgatgga
     4201 agatgaagtg aacttctaaa agccgaaaaa ctcaagtatt atcttcaaaa tactagtgct
     4261 caatgagatg cttgatttga tcacaagaag actgcgaaag ccgctggcaa ccgcaagcta
     4321 ggtatcccac cgatggacta cgttttagag gctactggtt atgaatacgg agccaacgct
     4381 ctcatctgca taagaataca tcacccagat tatgtaaaga ttttcgatac ttctgtcaaa
     4441 aaatcattaa gatagataaa tgatttccgt ctagtcaaat tggttcagaa tgtagacaca
     4501 cagatggtaa gaagtcactc acaattcgag aatggacttg tcctatttgc cgtatacatc
     4561 ataatcgaaa cgtcaacgat agtatcaata ttttgaccaa gggctatgaa tacaagcatt
     4621 gccttagaaa acatcaagaa ccttaggaac aacggggata gcttggttaa taagagatac
     4681 cgctgtttag gcttgcaagt atactctttt atcaagaatt ccgtggcttt agtcatgaga
     4741 ggcttaatac tatgaaaatt ttctttagca tttttgattt aggttccttt tctaattata
     4801 ataagatgac cactacagta acctactgaa atatataaac agccactgta gtaccatttt
     4861 caaagtagtc tatgagagga gaatcttcat tcttatgaac gctggaattg cggatatgaa
     4921 tttaataaaa aaaaccctta atgattttac ttccaattca atatcaaaag gtactggtat
     4981 caatttaagc acaataaaaa agctgaaaag tggtgaaaga tcagtggaaa agctgaatct
     5041 tttagatgct ataaaaataa cggaatttgc tatgaaaaat ggaaaagctg agattgaaat
     5101 atggagataa ttatcgtcta gtgaattact tgccacttag ctgaatttaa cgatccttgg
     5161 tgcttgaagg gggagattct tgggaataga gcatacttgc aagcctatgt ctttactaac
     5221 aacgatatct cttattaacc aagctatccc cgtagttcta aggcttttac ttttatctaa
     5281 gcaataatcg tattcaaagg aaatttttga cccttagaaa gtctcatttt atcagacgtg
     5341 agcttaggca ttgctgaatt ttgttaattc ggttttaggt tgtgctttga gcataatatg
     5401 aaagtattct ttatcacgat ttcattcatc taaggtaatg tgatgtgatt ctgaaattct
     5461 ttcaaaggca gtttttgcat aagctgacat tacatcatca atgacatgtt tacaatgttt
     5521 cactactaaa ataagggggt aaccaagaag aaaaactgaa tgattatttg tatctaattc
     5581 catggtatat caaccatttc ctatatagac tgattatgac atggattaaa ataaaaaggc
     5641 actatgtctt aattgtcggt tttcgagtta ccgaatggca ttcatcaccc acctatagag
     5701 gatgggcgac ttctgcctga aataagttac actacttata acttctaata aaattagatt
     5761 gagtcattat tatttaacat caacgatttt ccagtttcca tttttttgta atactaattt
     5821 gtactgaaag tagctagtgg tttttgatac attatcaagg tattttatct ttgtactcac
     5881 tagaaaattt tttccgtttt gtagataaac tggattctct aactccgaaa actttaagtc
     5941 aatattgatt ggtcgcatcg caccattttc aacataatac tccaattctt tttcagaagc
     6001 tgatggataa agtttaaaaa atgtttctaa aaaatcggtg atttcttccg ttgttttggc
     6061 atcaatttct gaatcgtttt ctacttgttt tgcttcatat tttgccttgt ctggctttcc
     6121 aatcattgtt ggcaaactag ttactaaatg attcctgttt tcatcttcaa agattgtcac
     6181 tcgatatgca gaagaaattg attgcgtctt ttttccctct gtaatatgtt gctccactaa
     6241 aaatgaaacg acaaattctt ccgagtgttt ttcaacatct agaattttta cagattgaac
     6301 ttcggaactc gtgggaatat ctgctcgaac catatcttgg attaaagcga gaccgttttc
     6361 tgtaaggtac tgttcgagat tactcattct cttttcaatt gcttctttgt tatttttcca
     6421 tgaaaaatat tctttcgcaa aatcctctgt aaaactttca acgccagaag tattcactac
     6481 cttctctttt ataaccactt tttcatgagt tgtatgttga tcaatggcgg tgaaattttt
     6541 ataaacgcca aaagcaagac tacaagacaa taaaagccaa agggcaagca ccatttttcg
     6601 atgcttaccc acggatacaa ctcgttcttt tttctttttt gggctctttt ccttttgatt
     6661 ccgttcaatt tttatcttca ttctttttcc tcttttctct tatttgtatc ggccagctcc
     6721 gataagatgc tgccgccaat agttttccgt tagattcgtc caccccactg gatctcctgc
     6781 atgaaacatg cgattctccc ctgcgtaaat gcccacatgg gtcacataag taccggcatc
     6841 ataggttgaa tgaaagaaaa ctaaatcacc tggtttggca tcttttagat caatatgagt
     6901 catggcatca tattgatcct gagccacccg aggaagtttc aggtcaactt tggcataaca
     6961 ccattgggtc aagccactac aatcaaaccc cgtttctgga cttgagccac caaacacata
     7021 ggccgttcct tcatacttaa atgcctcatc aaaaatttct tggactattt tgtcatcaaa
     7081 ctgagttgta gttaggtatt gcttcactaa taaacagtaa aacatattgc cataattata
     7141 ccgccaccca ccattttcct taatcgcgat tgggttgggg taatcgactt tttgaccacc
     7201 tgatttttcc tttgaaaaag attcagctaa agcaaaacta tgcttcttcc cgtttttccc
     7261 gacatgatct agatacccgc caccatagtt ataggcctga ataatactat cttgatcaca
     7321 ccctagttct ttggaacgct taaccaaaga cgcaaaatag agacagcctt gtttgatgga
     7381 tgcctcggta cttaatgaat taggtggtaa tccggctgac tcagaacttt gcataacgtc
     7441 ttccattgtg ccaccagatt ccacttgaat aatcgccaaa agaattggaa tatactctgt
     7501 tatatccgat tctttggcat acttttccac cattgcacgg tgtttcaata cttcttctga
     7561 gacactagtt ccgccaggag aagtgccaga actaccattt ccctcactgt cttcaccaaa
     7621 caacaaaccc acacacatca aaatacccat aaaagagatg gtcagaaaag ttaatgaaat
     7681 aacacccact ttcttcaagt tcattttttc tcacctgacc ttgattttgg acgatggttc
     7741 attctttttt gtactttttg attggtctgc tttggcagag tggacctctg tttcacttgt
     7801 tggaaagaat ttttcttact tgctgattgg cttttccctt ttgaaatgat ttcttgacta
     7861 gttagttttc gtttgatttc gggattcaga tttgctctca caatccgctt tggtgcttct
     7921 tttttcagca tcatatcttt ctgaggttga gctgctttat ctattggaat attcgccctt
     7981 ctttttccct gacgatttgt tgcttcactc agtatcttgc gtttttcgtc cattttcgca
     8041 tttcttcgtt gtcgttgttt ttctcgcaaa tccactcgat ccgctttttc ttggaacagt
     8101 ccgcgcttga attcttctgg tgcttttttc gacttttcga ttcctttatg gagattgtat
     8161 ttcaaattcg ttggcgtatt ccttacctga tcctttactt gtttagtctt atctttcacc
     8221 aaagcttggg tatccaaaac tttgccgatt tttctcccag ccaaattcat tcgggattgt
     8281 ttcttattat ttgaaactgg attctcctta gttaagtcag atagtatttc gtgatcgttc
     8341 ggtaatcgtg aattctttcg tagagaagaa ccggatggct taaatttgga ttttgattgt
     8401 tcctttgcca acttatttcc gactgctgca ccaccaccaa aagccaaagc tcgtcccaca
     8461 tttcgattga gttgccgcaa ttttcgattc attaacattt gcggttttcg catgacgcgt
     8521 cttcccattg actggctatc attactctgg aggttgaaca tactcataat gtcgcccaat
     8581 ttgaaataga taccggcaaa ggtcacaatt tgcagaaaag caaccatgaa aaatggatag
     8641 gttgccgaaa tattgaaaaa catcgtggag atgctaaatg cagtcgtaat caccaaagta
     8701 acacccgctc gcatcataat cgtattgaat aaacgaataa tcgccttctt tcctaaactt
     8761 tcataagtcg gcaacatgga caataagaaa ctaattggca gaaacatcgc aaagataatg
     8821 aagagaattt gcgagaacaa cataatccct gttagaagaa aaacaaagaa ggaaatgcca
     8881 atattgaaca ataccaaaaa gaccacggtc cctaaacggt tcatggtctt ggtaatactg
     8941 agattcgcat tgtcattgtc ttcaatctct gccttgaccg cttcttcccg atctttgcct
     9001 ttgttttcat ctggactcac agatagaatc ttgttgaccc ggtcttcacc aatttcttct
     9061 atgttggaat catcaaattg cagtagtaac caaggttgtt ggacttgaat cgaaaacaaa
     9121 ctatcccgaa tcaaatccac actatctttt ccttggcttt ctgaattggg tacaacgatc
     9181 tcggttccaa gggtaagggc cgcttcacta acatctgagc taaagtcatt gatttttgtg
     9241 atataggtag gcgcataagc aatgaacgaa cccgatagta gaaaaatcat cacaaaatta
     9301 atcacggctc gaactgcttt cgtggtttct cgttttaata atccggtata cgccacatac
     9361 acccccagag ctaaaatcat caataataga aacccaaaat aaaatccgga ggtctggagt
     9421 ccattttcag taataccagc caatgtttgg atattctttc caatactttc agccgtatcc
     9481 gaaatgaaat ctaatttgta agcctcttga accacataac ccgtggcgtt cgacaaatac
     9541 aaactcaccg tccaaatgaa attagtaatg gcataaagac catacatcac gcttttccct
     9601 aagccatcac cccaattcca aggcaaccaa tcccaagagc tatccacaaa gaaatctagt
     9661 tgatagttgt tcagtgaata tttggaatat agatttcctg cttcaactgt atcatcaact
     9721 agccctgtcg cctcggctac cgtaccaact aaactcaata gaactatcag agtgagtatg
     9781 ctaataaaaa cgattcccac aatccgaaaa agtttctttt tcatcccctc actccattct
     9841 ctcttgaaca ggtggacggg tatcaaaggc atggaagagt tcttcaaaga ctggatgtac
     9901 ctgaaccacg cctacccgac catacaaatc ctgcatcaag cattggccat tttccaaatc
     9961 tcgtaggcgt ttttgattgc tttcatcttc tcgatccaag ccaaagaatt ccaaggtttt
    10021 cttgatttca tgaatatcgg tactgcgaaa cgcaaacttc aacccgatat tattcttcaa
    10081 gcgttcatcc agtaaatcat cactattttg cgtgacaaag taaaccccgg cattcatagc
    10141 ccgcccagca cgaacgagct tattcgataa tgttttccct tgcgctactt gaagaaaact
    10201 ccacgcctca tctaagtcta caattttgaa gatttctcga ttactatgga taaagtccaa
    10261 ggcaaaagtg gaaatgacga ttagcatgga aacactaagc aattccatgg tggtatattc
    10321 ttcaaaagtg gtttctgcat ctggtaaaac caaatccgct acttgaatga tatttaactg
    10381 cctatctaaa ctaatcgact gggtaatcga accatctgag aaaagcaaat gggcaaaatc
    10441 ataatcggta aaggactcga tgtgatccgc gatattttcc gcaactggtg agccttcttt
    10501 tcgaagctca ttaattactt gtaataatcc ccgttgattg ctttgggtaa ccgtccgaat
    10561 ggccttacgc aacactggaa acttctcccc atctcgacta gaaattcctg ttaaaaaggt
    10621 cagaatatca attgctagac tttcagaatc cttctttttc tccataatca cataaggatc
    10681 aagtaatcct tgattttttg gcttactagt taagttgaga atattgattt catccgcaat
    10741 ttctggcaag gtttctttcc agccaccccg ttcccctttt ggatcgacaa tcacagcttg
    10801 tccaccaaaa aggacggcgt aataaactaa gagattgtta ctaaaggact ttccgccacc
    10861 gagtgaaccg aggaatgccg ctgctagcgc attggtaact gaacccttga ccccttgtga
    10921 ggccaatgcc ggtttcaggt aaacattgcg ccccgtatct acgttataac caaagtaaat
    10981 gccttccaac tcccctaaca tctgagtggc gccaaaacca agtccggcga gaaaatcaga
    11041 cgtaacatac tggatataat cattcatgta tcgcttacta gaaggtaaga attcttcatg
    11101 tagccccatc atatcgccaa aaggccggac tagttttaca ttggtatcat cataaaaatc
    11161 tagcacttca tcacaccggc gctttagttc atctactgat tcggcactta ctcgaaccac
    11221 atagctcagt ttgtacatgg attctttgga ctgatccaag gtagtttcca attcatctac
    11281 ggaatccaat gcatctaaga cattggaatt tgtttcattg tcagattgat aggcatggtt
    11341 gtccaagtct tttaattcct ttttcttatt gcgaacggta gcaagtgcct ttttgttcgt
    11401 cacaatctcc acattcatac tagtgtcaat tgggaatgta aattgttgtt gctggtaata
    11461 gaaaagttct gaggagggaa actccatttc ccccacaatt gtattaattg ttaagtacgc
    11521 tacatatgat tcatgattct catgttccat gcataagtac cggggctttt cttcaatcaa
    11581 acaacgactg ggacgtaata agtcgtaacg tttcaccaaa gtttccgact tcagcttttt
    11641 ctttggtagc tgaaattcat attcttcaaa tggtgtaccc ttttcgccat agatatgttc
    11701 aatcaaatac atcagatcac tcggtgtgac tcgtctgact ttaaatcttc gagccaattt
    11761 actttccatt agtttttcaa gcttggtata tcggcgaatt tcttcattgg ataaggaaac
    11821 aaaatcgccc atcaaatgat gattcactcc atagacaaat tcttgaaagc cggagaagaa
    11881 agatttcttg agattcttta gattgacctc ttcatctgtc gcaatcagtt tgaagccaat
    11941 aaaaaagcga taatcaatct gactatcgcc aatcatggat actaatgcct ctgtctgtaa
    12001 atcaattcgt tgtttcgcta cttctgttaa tcgcccggta atttcctttt ttgatcgttc
    12061 ttgcgtggca cgaatactac tttctgtggc aatttgtaag gcatgaatct tgccttcacg
    12121 attttgcgca atcaattgac gaaagttatc gtggacttga tatttctgtt caggtgacaa
    12181 aaaggagtaa ttgtaaggta ttaactcata gtaggcaaaa cattctccct cttgattaaa
    12241 gacaagatta ttttcaatat acttaatcgg gtacatagtt cacactcctt accagagtaa
    12301 tgggttcgtc ccatcgtttc ttctgttctt tgactttctt tcctgcgaaa gtgaccttaa
    12361 atcgtaagtg atagctaata aaagatcgta aaaatcccaa tggtttctta ccgtcaaacg
    12421 ttttttgcga catgaaccaa gtaactgcca ccggtatacc taagtatttt aaaaaggccc
    12481 cctctatcat agatagtgga ggcacatggg caaatacgat gacaaacagc aaggataaaa
    12541 caaaccaagc catctggtta aaagtcacag gaaaaggcag ttgaaagtca ttaattgcat
    12601 aaatgacctt ttcaactgcc caaatactgg tgtagctttt tattttcttc atcaaatcat
    12661 tcctttaaaa agaaggatag tttagaaatc aactaccctt caataatttt gttaatatgg
    12721 atactcaaaa acacctcgac tcgttaccaa ataattgcct ccaatctcca agtctctacc
    12781 acacgcatca aaatcaatat acgtcttcaa gtgttctggt acttctccaa aatcaccagc
    12841 ttctacaatc aagaaatatg ctacatcact catatcatcg caatctggat aatagataat
    12901 atcatccaca tgctctacca tctcctcaaa agaattgaag aaagcatgtt gaatctcaga
    12961 agcaacttca ccaactggcg ttccttcaag ttcctccgct aagccacaca accgattaat
    13021 ttcctcaatt ggcgtatact catcaatctc aaagggaagt tcataatcat gaattgcata
    13081 ttcctcgtat tcgtcattta acccaattcg ttctttcact tcatcaaaat cgacaggtgg
    13141 ggtaaaccac gcccccacca attcaccttc gttatatttc ccgaggttcg caatataaac
    13201 acgcatctgt tccatcgtgc ttccccctta cgcaccgaca attcggttaa acaaactgag
    13261 taagacatcc ttcaccccag aagcattaaa gaccaatccg accgcaatca aagcaatcac
    13321 caaaaagcca atcagtttgg aaaactcccg cttaaatcct aaaaacaaac caatgaccac
    13381 aattgccagt aagactaagg attg
//
LOCUS       DAFBVQ010000070        13113 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.073, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000070 DAFBVQ010000000
VERSION     DAFBVQ010000070.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13113)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13113)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13113
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.073"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(67..1746)
                     /locus_tag="LLC22_002333"
     CDS             complement(67..1746)
                     /locus_tag="LLC22_002333"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298952.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBK5435583.1"
                     /translation="MSTIKIIPLGGVRENGKNMYVAEVGEDIFILDCGLKYPENELLG
                     IDVVIPDFTYLEENIDRVAGVFLTHGHADAIGALPYLLSKISVPVFGTELTIELAKLN
                     VSRNEAAKGFKDFHVVDEHTEIDFGETVVSFFRTTHTIPDSVGINLKTKEGSIVYTGD
                     FKFDQTAIPMYQTDYARLAEIGKEGVLALLSESANAENPQPVASEAQIADEVFDTIKY
                     WEGRIIVACVASNLQRVQQVLDAAEKAQRKVVLTGQDFERIIRTAMRLEKLQLPSEDL
                     LVTLKDMKNYDPEELIILETGRMGEPIKSLQKMANGTHRNVKIEEGDLVYITTTPSIA
                     METIVAKTEDIIYRAGGTVKLISENMRVSGHANPNDLQLMINLMKPTYFVPVQGEYRE
                     LAAHADLAHAVGMPYKNIYITGRGDVLEYKNKRMSVAGTTSAENVMIDGLGIGDIGNI
                     VLRDRKILSEDGIFVAVVTISRREKKIISKPQITSRGFVYVKASRDLMKESSNMIETI
                     VEKHLESNDFEWSKLKQDIRDQLGRYLFEQTKRRPVILPVIMEATQRRNKK"
     gene            2294..3796
                     /locus_tag="LLC22_002334"
     CDS             2294..3796
                     /locus_tag="LLC22_002334"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435584.1"
                     /translation="MNFMKRAWKSTKVKWGRSLLLFAVFTAILIFVLAGLTIRSAAEE
                     AANQAQKEVGATVTLSANREASFKKQEQTSSSGSTTEERPDPGSFSLTPVSLTDAEKI
                     AELDNLKSYSFESSASAMAKDGITAITSSDSSEDSSETTDAGGEPAGGMGGNPQMTQA
                     DFQISGVSATAQNSNFSDGTAKITDGEGIDDSDKGTNNVVIDSTLAETNDLAVGDTFT
                     ITSTEDEDITYEMTIKGIYESSETSGSMGMKFNFMNPSNTLYTSYTFANELNGTSDDN
                     TIDSAIYTLSDPDKMDEFLKEAEKLIDTDTFSLQSNDSMYQSMLEPLNNVASFSKNVV
                     LLVAVAGIIILTLIIMITIRERRHELGVLLSLGESRSKIILQLFTEVAICMILALGVA
                     SLSGNVVANAVGQQLLDQQTETTTQNQQAPGGGQMPGNRQEQGGQRDGQQGTTNNPFA
                     VSDQVSELEINVKPAQLGLLAGVAFGISLFSVFLASIGILRLNPRKILLN"
     gene            3809..4471
                     /locus_tag="LLC22_002335"
     CDS             3809..4471
                     /locus_tag="LLC22_002335"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298949.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435585.1"
                     /translation="MLRTEQLGFWYQDPQDALYKDVELNFEAGKMYAILGASGSGKTT
                     FLSLISGLDAPKEGKVYYQDRSLNKIGLRSYRKNDVSIIFQAYNLLPYLSALDNVIAA
                     MEITKTKQENYRQVALDRLARVGIDEILAKKQVTKLSGGQQQRVAIVRAICCEHQLIV
                     ADEPTGNLDETTSQDIVKLFQEIAHEQNRCIIIVTHEIEVAKSCDEVFELKNKKFQKI
                     EV"
     gene            complement(4572..4775)
                     /locus_tag="LLC22_002336"
     CDS             complement(4572..4775)
                     /locus_tag="LLC22_002336"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CsbD family protein"
                     /protein_id="HBK5435586.1"
                     /translation="MADLKGRSKDMKDKVVGEGKEAYGKATDDKSKETEGKAQSLGAD
                     IKEKARNLGDEVKDKFSRKDEKK"
     gene            complement(4886..6070)
                     /gene="iadA"
                     /locus_tag="LLC22_002337"
     CDS             complement(4886..6070)
                     /gene="iadA"
                     /locus_tag="LLC22_002337"
                     /EC_number="3.4.19.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-aspartyl-peptidase"
                     /protein_id="HBK5435587.1"
                     /translation="MKIIRQIEVFAPDYLGKMDVLIAGGKILAVEEQLEGGYEGVEVE
                     ELSGEGKVLTPGFIDCHFHILGGGGEGGYQNRTPEVTLSQLTTAGVTTVVGCLGTDGE
                     GRDMTALISKAKGLEAEGISTYVYEGSYRLPVKTVTDSIIKDFLTIDKIIGIGEIAVS
                     DHRSSQPSFEEFARAVADARVGGMLSGKAGIINVHLGGGKRKLELLTRIVEETEIPIT
                     QFLPTHANRTPELFEACVAFAKRGGTIDFTASEDPDFWEKTDGEVRFSKALKRLIEED
                     VSLDNFTMTSDGQGSLPYFDENNHFLGLGVGSAKALLVGIKEAVQKESIPLEIALRAI
                     TSNPARILKLDKKGKIEIGADADLCILDKETLDIDTVIAKGEIMVQEKEVKVWGTFEK
                     SF"
     gene            complement(6227..7966)
                     /gene="yfcC"
                     /locus_tag="LLC22_002338"
     CDS             complement(6227..7966)
                     /gene="yfcC"
                     /locus_tag="LLC22_002338"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative basic amino acid antiporter YfcC"
                     /protein_id="HBK5435588.1"
                     /translation="MKKTNSSGKPKRDFTKLSTPHTYVIIFGVVIFAWILTFVVPAGK
                     FSTQDIEYKDANGETSTRTVLRQDSFRYAYELDKSYVFDQLEELQDHPAEREKLDVPE
                     KGLEKVIADGEKNLTQEKLDEISLTDDVLYDQYGENIYDTSKKLHKTAKIWGTDDFGG
                     FGFLNFVFEGLVSGDKYGSAVGIAALILVVGGAFGIIMRTGAIDAGIYAFISKTKGLE
                     RLALPLLFFAFSFGGATFGMAEEVIPFSMVMVPFVIALGYDSIVAVTVTYVASQVGNA
                     TSWMSPFSVAVAQGIAGIPVLSGATFRLIMWVVVTALAAGYMMIYAEKIRKKPESSLT
                     YKSDDYFRSHIKKTSDENKKFMLGHKLILLEMLVVLVWIVWGVTQKGYYIPEIASQFF
                     VMGLVAGIIAVLFKLDGMKVNDIASSFQSGAADLAGTAIVVGMAKGILLVLGGSDASV
                     PSALNTILHGIGTALTGVPAVIGAWAMYIFQSLFNLVVTSNSGQAALTMPIMAPLADL
                     VGVSRQVAVLAYQLGSGFMDAFTPVSASLIGVLGVARIEWAKWARFQIKMQGFLFVLG
                     TIFIMIAIAIGLQ"
     gene            complement(8739..9353)
                     /locus_tag="LLC22_002339"
     CDS             complement(8739..9353)
                     /locus_tag="LLC22_002339"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339759.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5435589.1"
                     /translation="MSLCYFDYYHQLEEKLRIEEPLMLQAGTWIAKQINQGGRLQIYA
                     SRTLSGVAFEFWDQTPDLVPSILIENPAGGVYETLEGAGQAIIDQLSVKSEDIFLLLS
                     NEGRNPAIIELAQWIKENGHPLIIVTGFDLSRSIKSQHSSGLRLFEFADLVLDNHANL
                     HDAVLTLPNLDPAICGTASLATIFLLQQVLYFTAKQLVQDTSGK"
     gene            complement(9959..10336)
                     /locus_tag="LLC22_002340"
     CDS             complement(9959..10336)
                     /locus_tag="LLC22_002340"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435590.1"
                     /translation="MGKLVAVAQSLLDILKWLMEGSNWIFVLPLLLISLFIMFRMVRK
                     KETFLIFIWYAASVGVATLMVELALGSWEACVFALFFAVLYLIIYIPYMKRKSRIGRK
                     GRHTTTFSSTDSLEQSRRTRRRR"
     gene            complement(10636..11517)
                     /gene="galU"
                     /locus_tag="LLC22_002341"
     CDS             complement(10636..11517)
                     /gene="galU"
                     /locus_tag="LLC22_002341"
                     /EC_number="2.7.7.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UTP--glucose-1-phosphate uridylyltransferase
                     GalU"
                     /protein_id="HBK5435591.1"
                     /translation="MKVKKAVIPAAGLGTRFLPATKAMAKEMLPIVDKPTIQFIVEEA
                     LDSGIEDILIVTGKEKRPIEDHFDANIELENNLREKEKTELLALVEETTQVNLHFIRQ
                     SHPRGLGDAVLQAKAFIGNEPFVVMLGDDLMKDDIPLTQQLMMDYEETQASAVAVMRV
                     PENETSKYGIIDPKTDSEKGRCRVKGFVEKPEMGKAPSNLAIIGRYLLTPKIFEILET
                     QEPGAGNEIQLTDALQTLNQTEAVYAREFKGKRYDVGDKLGYMKTNIEYGLQHSEIGT
                     SLSAYIIQLSKKLRTES"
     gene            complement(11560..12579)
                     /locus_tag="LLC22_002342"
     CDS             complement(11560..12579)
                     /locus_tag="LLC22_002342"
                     /EC_number="1.1.1.94"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291040.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-dependent glycerol-3-phosphate
                     dehydrogenase"
                     /protein_id="HBK5435592.1"
                     /translation="MKQKIAVLGPGSWGTALAQTLAENGHDVRIWGNVPEQIDEINKY
                     HTNQHFLPDLTIPESIIGYKELAEAVDNADAILFVVPTKAIRSVAQELIGKMNTKPII
                     IHASKGLEQDTHKRISEVLAEEIPEEKRQAIVVLSGPSHAEEVAVHDITTITAASIDQ
                     KAAAYVQKLFMNDYFRIYTNNDVIGVETGAALKNIIAIGAGAIHGLGFGDDAKAAIMT
                     RGLAEISRLGVAMGANPLTFIGLSGVGDLIVTCTSVHSRNWRAGNLLGQGHKLEEVLE
                     NMGMVVEGVATTKAAVELAQQLGVEMPITQTIYNVLYNGEDIKKAAKEIMLRDGKMEN
                     EFSLR"
BASE COUNT         3890 a         2770 c         2207 g         4246 t
ORIGIN      
        1 atttgttttt cgcaaaaaaa gagcaagacg agcactctat agagaggttc atcttactct
       61 ttttgtttat tttttatttc gacgttgagt agcttccata atgactggca agatcactgg
      121 gcggcgtttt gtttgttcaa ataagtaacg gcctaattga tctcggatgt cttgctttaa
      181 tttgctccac tcaaaatcat tgctttctaa atgtttctca acgattgttt caatcatatt
      241 gctgctttct ttcatcagat cacggctagc ttttacgtaa acgaatcccc gtgaagtaat
      301 ttgaggtttt gaaatgattt tcttttctcg ccgactgata gtgacaaccg ctacgaaaat
      361 cccgtcttct gacaagattt ttcgatcacg taaaacaatg tttccgatat cacctatgcc
      421 taatccatca atcattacat tttctgcact tgtagttcct gcaacactca tacgcttgtt
      481 cttatattcc agcacgtctc cgcgtccagt aatatagata tttttgtatg gcatccctac
      541 tgcatgagcc aaatctgcat gagcagctaa ttcacgatac tctccttgaa ctggcacaaa
      601 atatgttggt ttcatcaaat tgatcattaa ttgcaagtca ttaggattgg catggccaga
      661 aacgcgcata ttctcagaga tcaacttcac tgttccacca gctcgataaa tgatatcttc
      721 cgttttcgcc acgatggttt ccatcgcgat gcttggcgta gtagtgatat aaaccaaatc
      781 tccttcttca atcttgacat tacggtgtgt accgtttgcc attttttgca gagacttgat
      841 gggttcaccc attcggccag tttctaaaat gatcagttct tctggatcat agtttttcat
      901 gtctttcaac gtaacaagca gatcttcact tggtaattga agtttttcta aacgcatcgc
      961 tgtgcgaata attcgttcga aatcttgacc agtcaagaca acttttcgtt gtgctttttc
     1021 tgctgcatcc aatacttgtt gcactcgttg caaattactt gctacacaag cgacgatgat
     1081 acgcccttcc caatatttga tcgtatcaaa tacttcatct gctatttggg cttcagaagc
     1141 tacaggctga ggattttctg catttgccga ttcacttagt aaggctaaga ctccttcttt
     1201 gccgatttcc gccaatcgtg cataatctgt ttgatacatt gggatagccg tttggtcaaa
     1261 tttaaaatct cccgtataaa cgatactacc ttcttttgtt ttcagattga tccccactga
     1321 atctggtatc gtatgagtgg tacggaaaaa gctcactact gtttcaccaa agtctatttc
     1381 tgtatgctca tctaccacat ggaaatcctt aaatcctttg gctgcttcat tacgactgac
     1441 attcaatttt gctaactcga tcgtcaactc tgtcccgaat actggtacag aaatttttga
     1501 caacaagtaa ggaagtgccc cgatcgcatc tgcatgtcca tgtgttaaaa agacaccagc
     1561 tacacgatca atgttttctt ctaaatacgt aaaatcaggg attacgacgt cgatccccaa
     1621 caactcattt tcaggatatt ttagcccaca atctaaaata aaaatatcct cgcccacttc
     1681 tgcgacatac atgttttttc cattttcacg aacgccgcct aatgggataa ttttaatggt
     1741 actcacaaac ttcacctctt cttatgacat ccaagtttaa agatgtcgat tttcttcttt
     1801 atctaaatat atgagccatt ccaatgaagc atatgcaaaa tcactatttc tcaacttatg
     1861 gagaatcagc aggaaaatta ccagcacatc cgcgttctga cagttggatg ggcattttat
     1921 tttggatata cttcattaac aaaatggatc ttttgcgaaa cgctatagcc agaatactta
     1981 tataagtatt cagctgttcc ccattattat acaacaaata aactaaatcg ctagtatcag
     2041 caattgttag aacaactatg cacgtaaaaa tccctctgta gcatctagga tttcttttgc
     2101 tattcctctt tcatttcttc ttcgtcggtt tgaaacatac ttttttcatt ttaccacatt
     2161 ttttgcaata actatagtga ctttttatat atacagaacc tcatgttgat ggtgtgcaaa
     2221 cagcataaga tttaagctag ctttaagata ggttgtctat tatcaaatgc atctactagg
     2281 agggatgcaa aatatgaatt ttatgaaacg tgcatggaaa agtacaaaag taaaatgggg
     2341 acgttcattg ttattgtttg ccgtgttcac agccattctt atttttgtgc tagctggcct
     2401 cacgattcga agcgctgcag aagaagcagc gaatcaagca caaaaagaag ttggagcaac
     2461 agtgacttta agtgccaatc gagaagcttc atttaaaaaa caggaacaaa cttcttcaag
     2521 cggttctacc actgaagaac gtccagatcc aggcagtttt tctcttacac cagtttcctt
     2581 aacggacgcg gaaaaaatag ctgaattaga taatttaaag agttattcct ttgaaagttc
     2641 cgcctcagct atggcaaaag atggaataac tgccatcact agttctgatt caagtgaaga
     2701 cagttcagaa actactgatg caggcggtga acctgctgga ggaatgggcg ggaatccgca
     2761 aatgactcaa gcagactttc aaatcagtgg tgtgtcagca actgcacaaa atagtaattt
     2821 ttctgatgga acagcaaaaa tcacggatgg tgaaggaata gatgacagcg acaaaggcac
     2881 aaacaatgta gtcattgatt ctactctagc agaaacaaat gacctggcag tcggagatac
     2941 tttcacaatc acgagtactg aagatgaaga tatcacttat gaaatgacga tcaaaggaat
     3001 ttatgaatcc agcgaaacaa gcggcagtat gggtatgaaa ttcaacttca tgaatccgtc
     3061 gaatacactt tacacttctt acacttttgc aaatgaacta aatgggacat ctgacgataa
     3121 cacgatagat tctgctattt acactctatc tgatccagat aaaatggatg agtttctcaa
     3181 agaagctgag aagctgatcg acacagatac atttagctta caatcaaatg attccatgta
     3241 tcagtcaatg ttggaacctt taaacaacgt ggcaagtttt tctaaaaatg ttgttttact
     3301 agtggctgta gccggtatta tcatacttac tctgatcatt atgattacca ttcgggagcg
     3361 tcggcatgag ttaggcgtct tgctatcttt aggagaatcc agaagtaaaa tcattctcca
     3421 attgtttacc gaagtggcta tttgtatgat tcttgcatta ggagttgctt cgcttagcgg
     3481 aaacgtcgtc gcgaatgccg tgggacagca gctacttgac caacagacag aaaccacgac
     3541 acaaaaccag caagctcctg gcggtggaca aatgccaggt aacagacaag aacaaggcgg
     3601 tcaacgcgat ggtcaacaag gaaccacgaa taatccattt gctgtttctg atcaagtcag
     3661 cgaattggaa atcaatgtca aacctgcaca attgggacta ttagccggag tagcatttgg
     3721 aatcagtctg ttttctgtct ttttagcttc tatagggata ttaagattaa acccaagaaa
     3781 aatcctatta aactaaagga ggaatttgat gttacggaca gaacaattgg gattttggta
     3841 tcaagatccg caagatgcgc tttataaaga tgtagaactg aatttcgaag ctggaaaaat
     3901 gtacgctatt ttaggagcaa gtggttctgg aaaaacgact tttctttcgc ttatttctgg
     3961 actagatgca ccaaaagaag gaaaggtata ctatcaagat cgttcactga acaaaatcgg
     4021 gttaagaagt tatcgtaaaa atgatgtctc gattattttc caagcttaca acttgcttcc
     4081 ttatttatcg gctctagaca acgtcatagc agcaatggaa atcactaaga ccaagcaaga
     4141 gaattatcga caagttgctt tagatcgact ggctcgtgta ggaattgatg aaatattagc
     4201 aaaaaaacag gtgaccaaac tttcgggagg tcagcagcag cgagtcgcta tcgttcgtgc
     4261 tatctgctgt gaacatcaac taatcgtagc ggatgagcct actggaaatc tagatgaaac
     4321 aacttcacaa gatatcgtca aacttttcca agaaatcgcc catgaacaaa atcgctgtat
     4381 tatcatcgtg actcatgaga ttgaagtagc aaaaagctgt gatgaagtct ttgaactaaa
     4441 aaataaaaaa tttcaaaaaa tcgaagttta aaaaacagga taatgatcaa ataaaaaatc
     4501 cgaaccatat ctgtctcgca gatatggttc ggatttttta tttgcttgat tcaattagta
     4561 ataagtggtt tttatttttt ttcgtctttt cgagaaaact tgtctttgac ttcgtcgcct
     4621 aaatttcgag ctttttcttt gatgtcagca cctagtgatt gtgctttccc ttctgtttct
     4681 ttgctcttgt cgtctgttgc tttgccgtat gcttcttttc cttcaccgac tactttatct
     4741 ttcatatctt tagaacgtcc ttttaaatct gccattgtgc ttcctcctct tagtttgttt
     4801 attgatctac cttcagggta acatcaacaa cagatacaga caaacagaac gctcgttttc
     4861 taaaaaagat agttagagct gttgattaaa aacttttttc gaaagtcccc catactttga
     4921 cttctttttc ttggaccatt atttctcctt tagcgataac tgtatcaata tcaagcgttt
     4981 ctttatccaa gatacacaga tctgcatcag caccaatttc gatttttcct tttttatcca
     5041 atttcaatat acgtgctgga ttactggtta tagctcgtaa ggcgatttcc aaagggatac
     5101 tttctttttg cacagcttct ttgatcccta ctagcaatgc cttggcactt cctactccta
     5161 accctaggaa atgattgttt tcatcaaaat aaggcaagct tccttgtcca tctgaggtca
     5221 tcgtgaaatt atctaaagaa acatcttcct cgatcaatcg tttcagtgct ttgctgaagc
     5281 gaacttcacc atctgtcttc tcccaaaaat caggatcttc gctagcagtg aagtcaatcg
     5341 tgccaccacg tttggcaaat gccacgcaag cttcaaataa ttctggtgtg cgatttgcat
     5401 gagtaggcaa aaattgtgtg atcggaattt ctgtttcttc tacgattcgt gtcaatagct
     5461 ctagctttct ttttcctccg cctaagtgga cattgatgat cccagctttt ccggataaca
     5521 tgcctcctac acgagcatct gctactgcac gagcgaactc ttcaaaactt ggctgagaag
     5581 aacggtgatc ggatactgcg atttctccga ttccgataat tttatcaatt gtcaaaaagt
     5641 ctttgatgat agaatctgtt actgttttta ccggcaatcg gtacgaacct tcgtatacat
     5701 aagtggagat tccttctgct tccagacctt tcgctttgct gatcaacgca gtcatatctc
     5761 taccttctcc gtctgttccc aaacaaccga caactgtcgt tacaccagct gtagtcaatt
     5821 ggctcaatgt gacttctggc gttcgatttt gataaccgcc ttctcctcct ccacctaaaa
     5881 tatggaaatg acagtcaatg aaacccgggg ttagtacttt tccctcacct gaaagttctt
     5941 ctacttccac tccttcgtag ccgccttcta gctgttcttc tacagccaaa atcttcccac
     6001 cggcaatcag tacatccatt tttcctaagt aatctggtgc aaacacttca atttgtcgaa
     6061 tgattttcat acatttttcc tctttcttta agtataactg atgataggat cttaaaaaat
     6121 aatccaaacg ataggatctt tactcctttg attttaccgt aaaatgacgg ttcttggagt
     6181 ccttatctac tgtttggatt acttttttat ttacaggtct ccagtactac tgcagaccta
     6241 ttgcaatggc aatcatgatg aaaatagttc ctaaaacaaa caggaatcct tgcatcttga
     6301 tttggaatct tgcccatttt gcccattcga tccgtgcaac acctagcaca ccaatcaagc
     6361 tggctgatac gggtgtaaaa gcgtccataa aacctgaacc aagctgataa gcaagaactg
     6421 ctacttgtct ggatacacct actaaatctg ccagtggagc catgattggc atagtcaaag
     6481 ctgcttgtcc tgaatttgat gtaacaacca agttgaacaa actttggaag atgtacatcg
     6541 cccaagcacc aatgacagct ggaacaccgg tcaacgccgt cccgatccca tgcaaaatcg
     6601 tattcaaagc tgaaggaaca gatgcatcag atcctcccaa gacaagaaga atccctttgg
     6661 ccatacctac tacgattgct gtaccagcta aatcagctgc accagattgg aaagaagaag
     6721 cgatgtcatt gactttcatt ccatctaatt tgaaaagaac agcaatgatt ccagcaacta
     6781 atcccatcac aaagaattga gaagcgattt ctggaatgta atagcctttt tgagtcacgc
     6841 cccaaacgat ccagacaagg acaactaaca tctctaataa gatcaattta tgcccaagca
     6901 tgaatttttt attttcatca gatgtctttt tgatatgaga acggaaataa tcatctgatt
     6961 tgtaagtcaa cgaactttct ggttttttac ggattttttc tgcatatatc atcatataac
     7021 cagcggctaa tgcagtaaca actacccaca taatcaatcg gaatgtcgca ccagacaaca
     7081 cggggattcc agcaatccct tgagccaccg ctacgctaaa cgggctcatc caagaggtcg
     7141 catttccgac ttgagatgcg acataagtca cggttactgc tacgatcgag tcatatccta
     7201 acgcaatgac aaatggaacc atcaccattg agaatggaat tacctcttct gccatcccga
     7261 atgtagcgcc accgaatgaa aaagcaaaga ataatagcgg taaagctaaa cgctccagtc
     7321 ccttagtttt actgataaac gcatagatac ctgcgtcgat cgctccggta cgcataataa
     7381 taccaaaagc acctccaaca acaaggatca atgcagcgat ccctacagca gatccatact
     7441 tatctccaga tactagtcct tcaaaaacaa aatttaagaa accaaagccg ccaaaatcat
     7501 ctgttcccca tattttggct gttttatgca attttttaga agtatcatag atattttcgc
     7561 cgtactgatc gtaaagcaca tcatctgtca aggagatttc atctagtttt tcctgcgtaa
     7621 gatttttttc tccgtcagca atgacttttt ccaatccttt ttccggaaca tccagttttt
     7681 cacgttctgc tggatgatct tgcagttctt ctaattgatc aaacacatac gacttatcca
     7741 gctcgtaagc ataacggaag gaatcttgac gtaaaacagt acgagtactt gtttcgccat
     7801 ttgcatcttt gtattcaata tcttgcgtgc tgaactttcc tgctggaacg acaaaagtca
     7861 gtatccatgc aaagatgact acaccaaaaa taatgacata cgtatggggt gtcgataatt
     7921 tagtgaagtc gcgtttcggt tttcctgaag aatttgtttt cttcaaattt atttcttcct
     7981 ttcttttttc agtaattttg atgaataaaa aatggataat caaatgaatt atacagtaaa
     8041 aatgacattt ccacatgaat aatttattag aaaatcactt ttttctattt tgtttttttt
     8101 ctcctatgta tgattatttt tttctctttc catttatatt aagtatttta tttctctgtt
     8161 tttccttaaa attctttttt tatttttaga ttagagaaaa tctcgtcctg tttttttcat
     8221 tttacaatca ttgaaaaatt gaatttcatt gcaaaaaaaa taataaacac ttataaatat
     8281 ccattatcta tccttcaatt tttgtgtatt ttatttctat tagaaaaagg tatcctgttg
     8341 gacaattttg ttatatcagg taaacttcat tgcaataatg ataacaaatg tactataatt
     8401 actttgtaaa gagttttggg gaagactctt tcatcaacgt gtattaagag acaagaaaga
     8461 atccatatgg attctttctt gtctcttttt ccactacttt ttatttttct gacactacat
     8521 attcttataa ctcatttctc ataactgtga aacaacttat aaaaataaca aactttaaac
     8581 aaaacaagct taaaatcaaa gatgatccat cttaaaataa ctaaaacaaa aaaagtagtc
     8641 gttgttaatc ctcattaata atcgttttct ttttttcaaa cgctccattt ttatgtggaa
     8701 cattattttt ttaaggaact ttgtcaacat gtggataact attttccact tgtgtcctgg
     8761 actagctgtt ttgctgtaaa atacaaaact tgctgcagca aaaagatcgt tgcaagagag
     8821 gctgttccgc agatcgctgg atctagattt ggcaaagtca agactgcatc atgtaaattg
     8881 gcgtggttgt ccaaaaccaa atcagcaaat tcaaataatc gcaaaccact gctatgttgc
     8941 gatttgatac ttcgtgacaa atcaaatcca gtaacaatga ttaatggatg accattttct
     9001 ttgatccact gagctagttc gatgattgcc gggtttcttc cttcattcga aagaagaaga
     9061 aaaatgtctt ctgatttgac agaaagctga tcaataattg cctgtcctgc accttctagc
     9121 gtttcataga cacctccggc tggattttca atcaatatac ttggtacaag atccggggtt
     9181 tgatcccaaa attcaaatgc tacaccactt agtgtgcggc tagcatatat ctgcaatcta
     9241 ccaccttgat taatttgttt cgcgatccaa gtgccagctt gaagcatcag cggctcttct
     9301 atccttaatt tctcttccaa ttggtgataa tagtcaaaat aacataaact catttatctc
     9361 tcccgcctag ctatacttga catgaataga aacagctgcc taatctaagg aagtacataa
     9421 aaaaacagta gttagacagt aacacatgtg gtctttgctg tttcaaacac aaaaaaggca
     9481 ttgaacgaat acgcccaata ccttgacata gcaaataaaa caacgtgcag accatggaaa
     9541 atatctacat aggggtagaa ttttcaccct agattaggta caataaatta ggtcgatgca
     9601 ctgcattgac tatggcaaaa tgatcggtca gggtgtatgt gtgtgactgg tcattccctg
     9661 attcttagcg ccaactaagg gtcagggagc ctttttttat tcagctgttt ctatctgaat
     9721 ttattgtaag taatctctta tccaagtgca agcaagaaaa tacaaaaaaa cattggtatg
     9781 atttatatat atataaataa cataaaaaaa ggaatggctt atcccgatac aacaagcatt
     9841 cctttaaaaa agattctttt atataagtga aaaaagcttt tttccaccaa ttaaataaat
     9901 ctctcatctc aatagtttat ccattatttt atcttttttt gcgtatacct actaaatatt
     9961 accgtcttct tctcgttctt ctactttgtt cgagagaatc tgtactagaa aaagtagttg
    10021 tatgtctacc ttttctgcct atccgagact ttcttttcat atatgggata taaatgatta
    10081 gatacagtac agcaaaaaat aaagcaaata cgcaagcttc ccaactacct aacgccaatt
    10141 caaccatcaa ggtagcaacc ccaacggatg ctgcatacca gataaaaatc agaaacgttt
    10201 ctttttttct gaccatgcga aacatgataa atagactaat aagcaatagt ggcaacacaa
    10261 atatccaatt gcttccttcc atcagccact tgagtatatc aagcagcgac tgtgcaacag
    10321 cgactaattt tcccatagtg aacacacacc tttttttata attaaaaaat tcgccttttt
    10381 attctactat gaatcttctg gcttggcttt catttctctt atgtaatcat tttcttttat
    10441 acaacttaaa aaaaaattaa accattagca taatattttc tgaatctatt cacgaaagtc
    10501 tttttctatc tttcgttttc cacgactcaa ctgatctaga gtcaaaaaac taaaacgaca
    10561 gttgcgcaaa tgacgcacaa gctgccgctt taataacaaa tagcctttca ttctcagcag
    10621 gccacttatt tccagttaac tttctgttct tagcttttta ctcaactgga taatatatgc
    10681 acttaatgaa gtcccaattt ccgaatgttg aagtccatat tcaatatttg tcttcatata
    10741 tcctaactta tcgcctacgt cgtatctttt tcctttaaac tctctcgcat agaccgcctc
    10801 tgtctggtta agagtctgaa gtgcatccgt tagctgtatc tcgtttcctg ctcctggttc
    10861 ttgagtttct aatatctcaa atattttagg agtcagtaga taacgtccga taatggctaa
    10921 attacttggt gcttttccca tttcaggttt ttctacaaac ccttttactc tgcaacgacc
    10981 cttttcgcta tctgttttag gatcaataat tccgtattta gatgtttcat tttctggtac
    11041 acgcatgacg gcaacagcgg aagcttgtgt ttcttcataa tccatcatca attgttgagt
    11101 caatgggata tcatctttca tcaaatcatc ccccagcatg acgacaaacg gttcatttcc
    11161 tataaatgct tttgcttgaa gcacggcatc ccccagtcct cttggatgag attgacggat
    11221 gaagtgaaga ttgacttgag tcgtttcttc aactaaagcg agtaattctg ttttttcctt
    11281 ttcccgcaaa ttgttttcca attcgatatt tgcatcaaag tgatcttcaa tgggtctttt
    11341 ttcttttccc gttacgatca agatgtcttc gattcccgaa tccaatgctt cttccacaat
    11401 aaactggatc gttggtttat ccacgattgg aagcatttct tttgccatgg cttttgttgc
    11461 cggcaaaaaa cgtgttccta gcccagcggc aggaatgact gcttttttga ccttcacttg
    11521 ctgttcctcc taaacgacga ttaactattg atcatctatt taacgaagag aaaattcatt
    11581 ctccattttt ccgtcacgta acatgatttc ttttgctgct tttttgatat cttctccatt
    11641 atacaaaaca ttatagattg tttgagtaat tggcatctca acacctagct gttgagctag
    11701 ctctactgct gcttttgtcg ttgccacacc ctcaacgacc attcccatgt tttctagaac
    11761 ttcttccagc ttatgtccct gtcctaacaa gttaccggca cgccaattgc gagaatgaac
    11821 acttgtacaa gtaacgatca agtcccccac accactcaaa ccgataaatg tcagaggatt
    11881 ggcacccatc gcgacaccaa gacggctgat ttctgccaat cctcgagtca tgattgctgc
    11941 ttttgcatca tctccgaatc ctaatccatg gatagcgccg gcaccaattg caatgatatt
    12001 tttcagtgct gcaccagttt ctacgccaat cacatcatta tttgtataaa tcctgaaata
    12061 atcattcatg aacagttttt gtacataggc tgctgctttt tgatcaatac ttgcagctgt
    12121 aattgttgtg atatcatgta ctgccacttc ctcagcatgg ctaggaccag ataatacaac
    12181 aattgcctgt cttttttctt ctggaatttc ttcagccaaa acttctgaga ttcgtttatg
    12241 cgtatcttgt tctagtcctt tacttgcatg tataatgatt ggcttagtat tcattttacc
    12301 aataagttcc tgtgcgactg aacgaatcgc ttttgttgga acaacaaata aaatagcatc
    12361 tgcgttatcc actgcttctg ccaattcttt atatccgata atcgattctg ggatcgtcaa
    12421 atcaggtaaa aaatgctgat ttgtatgata cttattgatt tcatcaatct gttcaggtac
    12481 atttccccaa atacggacat catgcccgtt ttctgccaat gtttgtgcta aagcagtgcc
    12541 ccaagatcca ggaccaagaa ctgcgatttt ttgtttcatg gatattcctc caaataaata
    12601 attgataatt tccattatag tatacatttc ttaaagttgg gactaatttc cattgttttt
    12661 aagtgtttgt ttacttcttt tatcgttttt acttgaaata atcaatgata tgttacaata
    12721 gtctacattt tatttttaca ctcgttatgc tttgcttgtt cctaagagga agcagttttg
    12781 acaatgttac taccagcatt actattagga ggttaggaaa cttctcctag tgagtattga
    12841 tttaaaatac ataagagaca gattgaacat ttctaaatct gtcaggtcct gcaacggaca
    12901 gattgtctct gttgacggtt gacataggaa cttttgtttt agtcaacatt ctggatacaa
    12961 aacgctatgt aaactggcgc aactcgttgt acttggactt ttactacgga tccatgcaac
    13021 aactaaatag tactattgca taacaaaaaa tggttggcac ccacatgtcc cattaaacag
    13081 attataagtt gaactgtaga taatgcaaaa aat
//
LOCUS       DAFBVQ010000071        13049 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.074, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000071 DAFBVQ010000000
VERSION     DAFBVQ010000071.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 13049)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 13049)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..13049
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.074"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(77..149)
                     /locus_tag="LLC22_002343"
     tRNA            complement(77..149)
                     /locus_tag="LLC22_002343"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(114..116),aa:Lys,seq:ctt)
     gene            530..1099
                     /locus_tag="LLC22_002344"
     CDS             530..1099
                     /locus_tag="LLC22_002344"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1836 domain-containing protein"
                     /protein_id="HBK5435593.1"
                     /translation="MEKMRQQLMEWGKELETFRLPHWEELPDLELYMDQVRTLVDRYL
                     SPVIQGEKHPLLTSSMVNNYVKLGLIPAPVKKRYNKEHVAFLLAITTLKQVLTIPEIK
                     EGILFQGKTVGIREAYNLFCDEQEAAVWMVSQLAQGKSHPQKFDQATPVEYIAVRAAT
                     LSFAMKLLAEKTIVLETEYLKEEKTNEKQ"
     gene            1086..1946
                     /locus_tag="LLC22_002345"
     CDS             1086..1946
                     /locus_tag="LLC22_002345"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DegV family protein"
                     /protein_id="HBK5435594.1"
                     /translation="MKNNKIAILVDSGTDVPEELIKKYEMYMIPLKIIYKDQVYTDKI
                     DITSEEIYQRLPEEIPGTSLPDGESITEIFEQIKKDGYEKVLAVTISSGLSGTYNVVR
                     LIAQQQEELEAYVLDTKNIGIGAGFSAIQAAKWLEEGVEWDQLISNLNELVERTKVFF
                     NVATLEYLQKGGRIGLVASIVGTALKLNPIISCNEEGIYYTVGKARGRKKSLDKTVAY
                     VKEKIGNAKVFNLAVAHGDAKEEAIEMEARLKREFPQANQIYFGQISPALVVHTGPGL
                     LGVGVQVLEG"
     gene            2136..2840
                     /locus_tag="LLC22_002346"
     CDS             2136..2840
                     /locus_tag="LLC22_002346"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5435595.1"
                     /translation="MKKVLVVDDEKPISDIVKFNLAKEGYDVYTAYDGEEALEKVAEV
                     EPDLILLDLMLPKMDGLEVAREVRKTYDMPIIMVTAKDSEIDKVLGLELGADDYVTKP
                     FSNRELVARVKANLRRGATAAKEPEEAAPAELTIGDLTIHPEAYMVTKRGETIELTHR
                     EFELLFYLAKHLGQVMTREHLLQTVWGYDYFGDVRTVDVTVRRLREKIEDNPSHPNYL
                     VTRRGVGYYLRNPEQE"
     gene            2845..4680
                     /gene="walK"
                     /locus_tag="LLC22_002347"
     CDS             2845..4680
                     /gene="walK"
                     /locus_tag="LLC22_002347"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall metabolism sensor histidine kinase
                     WalK"
                     /protein_id="HBK5435596.1"
                     /translation="MKRKVRFFRSVNFKIAITFILILLISIEIIGAYFIRGLERSTIN
                     TFIKDMNQTVESLATTISPELNRKDNADDEEVNANIKRFIENSATSDIIEIRVVDEKG
                     IIRGTTDVNEQSAVGKKNDYVDINDFTTKRYVALDNDDKRVNINVQPILSPTGDAVIG
                     ALYVKSNIEQKYSEINNTAVIFFTASLIAAFISMIVSVLVARSITQPIGEMREQAIRI
                     ARGDYSRKVKVHGQDELGQLADTFNQLAERIEEAQDTMEAERNRLDSVLSHMTDGVIA
                     TDRRGKVITINDMAVSLLDIKNEEAIGQSILTLLDIEEEYTLRKLLEDPNEMVLDRST
                     STLESDQMILRVDFSMIRRESGFISGLVAVLHDVTEQEKTERERREFVSNVSHELRTP
                     LTSMRSYIEALSEGAWKDEEVAPNFLKVTLDETDRMIRMINDLLNLSRMDTGNTQLQL
                     EYVNFNELVNFVLDRFDMMVGNQEKNYKIRREFTQRDLWVEVDTDKIIQVVDNIMNNA
                     IKYSPDGGTITCRLLETHNNVVLSITDQGLGIPKKDLNRVFERFYRVDKARARAQGGT
                     GLGLAISREVIKAHRGAIWAESKEGKGSTFYISLPYEPYEEEWWE"
     gene            4677..5993
                     /locus_tag="LLC22_002348"
     CDS             4677..5993
                     /locus_tag="LLC22_002348"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435597.1"
                     /translation="MRISEKVVRIGLILMVALSIYFSYAIWLSPAGKSSINVDETNTQ
                     MIESQSNRKTSEVFLPLHVTWHHSGMIQETNSENLVYRLQLIIDKARFGKLSEVVSGD
                     KSQFEQVKNLNSGFELAYNAPFLLREYKEAFDLDLDVSNLAKESENMYFTRIQFDQGN
                     KKIRFLNYSNHLVYEANISLNWTDINKELTAKDTKWTEMTTEPSTIDTQYATKHSIKL
                     KKYSYILSQQPYTLFRNAFFQKPDSVKNNDESNELIFYGGNETMSIHSETQVVDFRGE
                     LPEKKENASVFSESFPYISKLGSSLGNLRYFDRSDNTIDYRIFVEGFPVFGTDSRGQI
                     GVEVGGETNGSVQVNIQTSLNTIQVPIPSDEEVELASTNEIIQQLKAKGADSNKIGSV
                     IVGYTWQNVKETNRVVDLLPEWYVKYKDNWYSANDLLEKLPGLEAN"
     gene            5994..6863
                     /locus_tag="LLC22_002349"
     CDS             5994..6863
                     /locus_tag="LLC22_002349"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738649.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="two-component system regulatory protein YycI"
                     /protein_id="HBK5435598.1"
                     /translation="MDFKKIEWIFFVAFLGLNVFLFSSYHDAVYQENNVIRSNQTESI
                     QQRLASDDITYTGKISSENKQGYYLSAEQTNLSTSLANYRKAGKSGLLASGVFLDGDV
                     LTKSLSSSDAEKNVIDPDKISSSLEDFLSNKDNILFGNDYVYTKNFSHLEEEPLEIQA
                     SQEYEGIPFNDDTAKIVLSLEKNDNDYSITKYMQTHLSDIEQLREKTELYTEEEAINT
                     LYINNKIPRGSKILWRQLAYSCILKVREKNVYVPVWHVAIETSDKVVQIESVNAFSNT
                     IVTNNTVPKVEDQ"
     gene            6918..7727
                     /locus_tag="LLC22_002350"
     CDS             6918..7727
                     /locus_tag="LLC22_002350"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK5435599.1"
                     /translation="MAEEKPAFKISILASGSSGNSLYIESEKKRLLVDAGLSGKKITS
                     LMAQIDRTPDQLDGILVTHEHRDHIHGVGVLARKYHLDVFANQQTWEAMEPLIGNVPV
                     EQKHLFEMGKVRTFGDIDIESFGVSHDAAAPQFYRFHKENRSFVMLTDTGYCSDYMRG
                     VIENADGYLMESNHDLEMLRMGPYPWNLKQRILGDRGHLSNEDGALVMTDVIGNRTKR
                     IYLGHLSKENNMKELAHLTMENVLKEKDFGVGHDFEIYDTDPDEATELFSI"
     gene            complement(7830..8459)
                     /locus_tag="LLC22_002351"
     CDS             complement(7830..8459)
                     /locus_tag="LLC22_002351"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294128.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)H-binding protein"
                     /protein_id="HBK5435600.1"
                     /translation="MKIALIGATGHAGSFILDEALSRDLDVTAIVRHPEKLPSDVPFI
                     QKDLFELTTTDLASFDVVVDAFNAPKGKEEMHQTSLSHLIEMLEGTDTRLIVVGGASS
                     LFLDTEKTTRMIDQVPKNAPFYPTAFNMYEGLLKLKQSKNLHWTYISPASLFDPHGKR
                     TGTYLLSDDYLQRNAAGDSTISMADYAIALVDEILDEKHEKQHISVVSR"
     gene            8629..9921
                     /locus_tag="LLC22_002352"
     CDS             8629..9921
                     /locus_tag="LLC22_002352"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340257.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5435601.1"
                     /translation="MKEWLDRAFLPMITSVVNLRPLTALRNGMTYTIPIIIVGSLFFL
                     FAHFPVDYIAQWIDKTGFSMYFTQVYQATFDVIAFWIVFAIAYAYAKEEDIDRLPVGI
                     TALSAYLLLIQPLNTQIDTVWTGAEGILGAVTTGLIIGWGYARLVRLAKGWKQREKIP
                     ENVWQSFTSLIPIIVIVTFTLIGSAVFQQLFRMTVVQGVWTYVQLPIQSFIDTLFGVL
                     LLGFFVPFLWLFGLHGSAMVNGLVSPVLQANSLANAEILASGQELTVANGGHIVTQQF
                     LDQFMTVTGAGLTLGAVFFMTVFAKSKKYRELGNLALLPAFFNINESIIFSTPIVMNP
                     MMAVPFIFAPVVSGLITYSALYFGFVPLFTAVQVPWTTPPILSGFLVGGVPAAILQGI
                     VLSISFFIYFPFLKKIDSANCKKERQTKNDGAAEKMND"
     gene            complement(9997..10659)
                     /locus_tag="LLC22_002353"
     CDS             complement(9997..10659)
                     /locus_tag="LLC22_002353"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CPBP family intramembrane metalloprotease"
                     /protein_id="HBK5435602.1"
                     /translation="MSLKKYSFLSIFCYGLIFISPLILASIGLVKSTSELITATAVMY
                     ILGAVVLAIFYFKQREPLAIESAVKKASAPKIVIYGLVGIFVALILQSIAVMLESVLF
                     GKATPSENTQNIIQMIMEAPAFILATTVAGPIMEEFVFRRSILGIISRYSNFWVGAVI
                     SSLLFAFAHNDGHLLIYFFLGFFFSLEYKATGRIWTSMITHVGMNTLVVLVQLAVQKG
                     LV"
     gene            10884..11168
                     /gene="groES"
                     /locus_tag="LLC22_002354"
     CDS             10884..11168
                     /gene="groES"
                     /locus_tag="LLC22_002354"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738650.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="co-chaperone GroES"
                     /protein_id="HBK5435603.1"
                     /translation="MLKPLGDRVIIEVAKEEEKTVGGIVLASAAKEKPQTGTVVAVGE
                     GRLLENGEKVPAAVKAGDQVMFEKYAGTEVKYEGKEYLIVAGKDIMAIVE"
     gene            11219..12844
                     /gene="groL"
                     /locus_tag="LLC22_002355"
     CDS             11219..12844
                     /gene="groL"
                     /locus_tag="LLC22_002355"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736685.1"
                     /note="60 kDa chaperone family; promotes refolding of
                     misfolded polypeptides especially under stressful
                     conditions; forms two stacked rings of heptamers to form a
                     barrel-shaped 14mer; ends can be capped by GroES;
                     misfolded proteins enter the barrel where they are
                     refolded when GroES binds; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="chaperonin GroEL"
                     /protein_id="HBK5435604.1"
                     /translation="MAKELKFAEDARAAMLRGVDKLADTVKVTLGPKGRNVVLEKSYG
                     SPLITNDGVTIAKEIELEDHFENMGAKLVSEVASKTNDIAGDGTTTATVLTQAIVREG
                     LKNVTAGANPLGIRRGIELATKAAVEELHNISTVVDSKEAIAQVAAVSSGSDKVGHLI
                     ADAMEKVGNDGVITIEESKGIETELDVVEGMQFDRGYLSQYMVTDNDKMEAVLENPYI
                     LITDKKISNIQDILPLLEQILQQSRPLLIIADDVDGEALPTLVLNKIRGTFNVVAVKA
                     PGFGDRRKAMLEDIAILTGGTVITDDLGLELKDVTIENLGNASKVVVDKDNTTIVEGS
                     GEKEAIEARVQLIKNQIAETTSDFDREKLQERLAKLAGGVAVVKVGAATETELKELKL
                     RIEDALNATRAAVEEGMVSGGGTALVNVISKVSAVEAEGDVATGIKIVVRALEEPIRQ
                     IAENAGYEGSVIVDKLKNVELGTGFNAATGEWVNMVEAGIVDPTKVTRSALQNAASVS
                     ALLLTTEAVVADKPEPAAPAAPAMDPSMMGGMM"
BASE COUNT         4338 a         2254 c         2824 g         3633 t
ORIGIN      
        1 taaaaaaaga acagcgtaaa tgttttcgaa atgctttcgc accaacattt acctgttccg
       61 tgggtttggc acccaatggg ccgtgagggg ctcgaacccg cgacccgctg attaagagtc
      121 agctgctcta ccaactgagc taacggcccg tacaaaaagt acttaataat agtagcacta
      181 agaattttaa aatgcaagac tacatttaaa gaaaatcaga aaaatcttta cttccttata
      241 ggaaatcatt catagattat tcacatttgc tcgctattat ataagcatac caacaaacaa
      301 agttcttgca agagaacaaa ccctaacact tttttcattt tttactcctt tcccgccgtc
      361 tccccggcgg gtctcctgtt cttaacgata aaagacaaga aggcttagcc ttcttgtttt
      421 ttgttttcat ggaatcccgc taatcaaatc acctagttaa agcaactaga ttgaatgttt
      481 atcataagtc tgatatcatg tttatgaaat gaaaaaagga gcggttatga tggaaaaaat
      541 gcgtcagcaa ttaatggagt gggggaagga actagaaaca ttccgtctgc ctcactggga
      601 agaactccct gacttagaac tttatatgga ccaagtcaga acgttagttg atcgttatct
      661 ttcacctgtg atacaaggag aaaagcatcc attgcttacc tcttctatgg taaacaatta
      721 cgttaaacta ggtttgatac cagcaccagt taaaaaaaga tataacaaag aacacgtagc
      781 atttttactt gcaatcacta cgttgaaaca agtattgact attcctgaaa tcaaagaagg
      841 gatattgttc caaggaaaaa cagtaggaat tcgtgaagcc tataatctat tttgcgatga
      901 acaagaagca gctgtgtgga tggtcagcca attagcacaa ggtaaatctc atccgcaaaa
      961 attcgaccag gcaacccctg tagaatatat tgctgtaaga gcggcaactt tatcgtttgc
     1021 aatgaaactt cttgcggaaa aaacgattgt tctagaaacc gaatatttaa aagaggagaa
     1081 aacaaatgaa aaacaataaa atcgcaattt tagtagattc aggtacggat gtgccagaag
     1141 aattgataaa aaaatacgag atgtatatga tcccattgaa aattatttat aaagatcagg
     1201 tatatacaga taaaattgac attacctctg aagagatcta tcaacgtttg ccagaggaaa
     1261 tccctggtac atctttgccg gatggtgagt cgatcacaga aatctttgag caaatcaaaa
     1321 aagacggtta tgaaaaggta cttgcggtaa caatttccag tggattgagc gggacatata
     1381 atgtggttcg tttaattgca caacagcaag aagaattgga agcatatgta ctagatacga
     1441 aaaatattgg tattggtgca ggtttttctg cgatccaagc agcaaaatgg ctggaagaag
     1501 gagtagaatg ggatcaactg atcagtaatc tgaatgagtt agtcgaaaga acaaaagttt
     1561 tctttaatgt tgcgacattg gaatatcttc aaaaaggtgg acggatcggt ttagttgctt
     1621 ctattgtagg aaccgcttta aagcttaacc caatcatctc atgtaatgaa gaagggattt
     1681 attacacagt aggaaaagct aggggacgta aaaaaagttt ggataaaacg gttgcttacg
     1741 tcaaagaaaa aatcggtaat gcaaaggtct tcaacttagc tgttgcccat ggggatgcga
     1801 aagaagaagc aattgaaatg gaagcgagac ttaaaagaga gttcccacaa gcaaaccaaa
     1861 tctactttgg ccagatttct ccggcattag tagtccacac tggtccggga ttattgggtg
     1921 tcggtgtaca agttttagaa ggataaatca aaaaaaggaa acactgaggt gaaaatcagt
     1981 gttttccttt tttattgaag ttagaacaaa aaataataaa gtattttgca ctttcatttt
     2041 aattttctct tttgttttat aggcaaagat gaaacaaaag cagaaatacg gtataatgag
     2101 aaggtatgac aataatatat aagaggtggc tctttatgaa aaaagtttta gttgtcgatg
     2161 atgagaagcc gatttcggat atcgtcaaat tcaatttagc caaagaaggc tatgatgttt
     2221 atactgcata tgatggggaa gaagccttgg aaaaagttgc tgaggtagaa cctgatttga
     2281 ttttacttga tttgatgcta cctaaaatgg acggcttaga agttgctcgt gaggtacgca
     2341 aaacttatga tatgccgatc attatggtaa cagccaaaga ttctgaaatt gataaagtcc
     2401 taggcttaga gttaggcgcc gatgattacg tgaccaagcc attttccaac cgagaattag
     2461 ttgcacgtgt caaagcaaat cttcgtcgcg gtgccacggc tgcgaaggaa ccagaagagg
     2521 cagcacctgc ggaattgacg attggtgatt tgacgatcca tccagaagct tacatggtga
     2581 cgaaacgagg agaaacaatc gagttaacac atcgtgaatt cgaactactc ttttacttgg
     2641 cgaagcacct tggacaagtg atgacaagag aacatttatt acaaacggtt tggggttatg
     2701 attattttgg agatgtacga acagtggatg taactgtacg tcgtttgcgt gaaaagatcg
     2761 aagataatcc aagccatcca aattatttag tgacacgtcg tggtgtcggt tactatttgc
     2821 gtaacccaga acaggagtaa ttggatgaaa agaaaagtcc gcttttttcg atcagtcaat
     2881 tttaagatcg ctattacctt tattctgatt ttattgatct cgatcgaaat tattggtgcc
     2941 tactttatac gtggtttaga acgttccacg atcaatacat ttattaaaga tatgaatcaa
     3001 acggtggaat cattagcaac aacaatcagc ccggaattga atcgaaaaga taatgcagat
     3061 gatgaagagg taaatgcgaa tatcaaaaga tttattgaaa acagtgcgac tagcgatatc
     3121 atcgaaatac gggtcgttga cgaaaaaggg atcatccgag gaacaaccga tgtcaatgaa
     3181 caaagcgctg tgggaaagaa aaatgattat gttgatatca atgatttcac gactaaacgt
     3241 tatgttgctt tagataacga cgataaacgg gtgaatatca atgttcaacc gatcctgtcc
     3301 ccgaccggcg atgccgttat cggggctctt tacgtcaaaa gtaatatcga acaaaaatat
     3361 tcggaaatca ataacacagc agtcattttc tttactgcct cactaattgc ggcatttatt
     3421 tcaatgatcg tatctgtttt agttgctcgt tcgattacac agccgatcgg tgaaatgaga
     3481 gaacaagcca ttcgaatcgc tagaggagac tacagtcgga aagtcaaagt gcatggacaa
     3541 gatgaacttg gacagctggc tgataccttc aatcagttag ctgaacgtat tgaagaagct
     3601 caagatacaa tggaagctga acgcaatcgt ttggatagcg tgctatccca tatgacagac
     3661 ggcgtcattg cgacagatcg caggggtaaa gtcattacga tcaatgatat ggctgtttcc
     3721 ttgctagata tcaaaaacga ggaagcaatc ggacaatcga ttttgacact tttagatatc
     3781 gaagaagaat atacgttgcg gaaattatta gaagatccaa acgaaatggt acttgaccgt
     3841 tcaaccagta cattggaaag tgatcagatg atcttgcgag tagacttttc tatgatccgt
     3901 cgcgaatcag gttttatcag cggattagta gctgtcttgc atgatgtgac agaacaagaa
     3961 aaaacagaac gggaacgtcg tgaattcgtc tctaatgttt cccatgaact tcgtacaccg
     4021 ttgacaagta tgcgtagtta tatcgaagca ttgagcgaag gtgcgtggaa agacgaggaa
     4081 gtagcaccaa attttttgaa ggtaacgcta gatgaaacag accgaatgat tcgaatgatc
     4141 aatgacctct taaatctatc tcgcatggat acaggtaata cccagcttca attagaatat
     4201 gtcaatttca acgagttagt gaattttgtt cttgaccggt ttgatatgat ggtgggaaat
     4261 caggaaaaaa attataagat ccgtcgtgaa tttacgcaaa gagatctttg ggtcgaagta
     4321 gatacagata aaatcatcca agtagtcgat aatatcatga ataacgcgat caagtattca
     4381 ccagatgggg gaacgattac ttgtcgctta ttagaaacgc ataataacgt ggttttaagt
     4441 atcaccgatc aaggattggg gattcctaaa aaagatctga accgagtgtt cgagcggttc
     4501 tatcgagtag ataaagcacg tgcaagagca caaggtggga caggacttgg attagctatt
     4561 tctagagaag tgattaaggc gcatcgaggc gctatttggg cagagagcaa ggaaggaaaa
     4621 gggtcgactt tttatatctc gctgccatat gaaccttatg aggaggaatg gtgggaatga
     4681 gaatctctga aaaagtcgtt cgtataggac tcattttgat ggttgcgtta agcatatact
     4741 tctcttatgc aatctggctg agcccagcag gaaaaagttc aatcaacgta gatgagacaa
     4801 acactcaaat gatcgagtct caaagcaatc gaaaaacttc cgaagtcttt cttccgcttc
     4861 atgttacatg gcaccattcg ggaatgatcc aagaaaccaa cagtgaaaat ctcgtgtacc
     4921 gattgcaatt gatcatcgat aaagcaagat ttggaaagct ttctgaagta gtttcaggag
     4981 acaaatcaca gtttgaacag gtgaaaaatc tgaactctgg ttttgagttg gcctataatg
     5041 cgcctttttt gctaagagaa tacaaggaag catttgattt agatttagat gtgtcgaact
     5101 tggcaaaaga aagcgaaaat atgtatttta ctagaataca attcgatcaa ggaaataaaa
     5161 aaatccgatt tttgaattat tcgaaccatc tcgtatatga agcaaatatt tcgttgaatt
     5221 ggacagatat caataaagaa ttaacagcaa aagacacaaa atggacagaa atgacaacag
     5281 aaccatcgac gatcgacacg caatatgcta cgaaacattc gatcaaactg aaaaagtata
     5341 gttatatcct gtcacagcaa ccctatacac tttttagaaa tgcttttttc cagaaaccag
     5401 atagcgtgaa aaataatgat gaaagcaatg aattgatttt ttacggtggg aatgaaacaa
     5461 tgtctatcca ttcggaaacg caagtagttg attttcgtgg agagctgcca gagaaaaaag
     5521 aaaatgctag tgtattttct gaaagtttcc cctatattag caaattaggc agttctttag
     5581 ggaacctcag atattttgac cgcagtgaca atacgatcga ttatcggata ttcgtggaag
     5641 gcttcccggt ttttgggaca gacagcagag gacagattgg tgtggaagtt ggcggtgaaa
     5701 cgaatggttc tgtgcaagtg aatatccaaa ccagtttgaa tacgattcaa gtgccgatac
     5761 cttcagacga agaagtagaa cttgcaagta cgaatgaaat catccagcag ttaaaagcta
     5821 agggagcaga tagcaacaag attggttcag tgatcgttgg ctatacatgg caaaatgtca
     5881 aagaaacgaa tcgtgtcgtt gatctcttac ctgaatggta tgtgaaatat aaagataact
     5941 ggtattcagc taacgacctt ctggaaaaat tacctggatt ggaggcgaat taattggatt
     6001 tcaaaaaaat cgaatggata tttttcgtcg cttttttagg gttgaatgtg tttttattca
     6061 gcagttatca tgacgcggta taccaagaaa acaatgtcat tcgctctaat cagactgaat
     6121 caatccaaca acgtctggct agcgacgata tcacttacac ggggaagatt tcgtctgaga
     6181 acaagcaagg ctattatctt agcgcggagc agaccaatct tagcacttca ttagcgaatt
     6241 atcgcaaggc tggtaaaagc ggcttgctgg caagtggtgt gtttttagac ggtgatgttt
     6301 tgacgaaatc tttatccagt tcagatgctg aaaagaacgt gatcgatcca gataaaatta
     6361 gtagttcctt ggaagatttt ttatctaaca aagacaatat tttattcggt aatgattatg
     6421 tgtacacgaa aaacttttct catttagaag aagaaccact agaaatccaa gcaagccaag
     6481 agtatgaagg catcccattc aatgatgata cagcaaaaat cgttctttct ttagaaaaaa
     6541 acgataatga ttatagcatc acgaaataca tgcagacgca tttatctgat atcgagcagc
     6601 tgcgcgaaaa gacggaactg tatacggaag aggaagcaat caatacattg tacatcaata
     6661 acaaaatacc aagaggatca aaaattttat ggcgtcagct agcttattcc tgtattctga
     6721 aagtccggga aaaaaatgtg tatgttcctg tttggcatgt agcgatcgaa acaagcgata
     6781 aagtggtcca aattgagagt gtcaacgctt tcagcaatac gatcgtgaca aacaatactg
     6841 taccaaaagt ggaagatcaa taaaaaagcg agtataatga aaaaagttta caaagtaaga
     6901 agggaagtag gagtcaaatg gctgaagaaa aaccagcttt taaaatcagt atcctagcaa
     6961 gtggaagttc gggtaattca ctttatatcg aaagtgaaaa aaaacggctt ttggtcgatg
     7021 caggacttag cggtaaaaaa atcacttcct tgatggctca aattgatcgg acaccggacc
     7081 aattagatgg aatacttgtg acgcatgaac atcgagatca tatacatggc gtgggtgtct
     7141 tggctcgtaa gtatcatttg gatgtttttg ccaatcagca gacttgggaa gcgatggaac
     7201 cactgattgg aaatgtacca gtggaacaaa aacatctatt tgagatgggg aaagtcagaa
     7261 cattcggcga tatcgatatt gagagtttcg gcgtctccca tgacgcagcg gctccgcaat
     7321 tttatcgttt ccataaagaa aatcggtcat tcgtcatgtt gacggacacc ggatattgca
     7381 gtgattatat gcgaggtgtc attgaaaatg ccgatggtta tttgatggaa agtaatcatg
     7441 atcttgagat gttacgcatg ggaccttatc cgtggaattt aaaacagcgt attttaggag
     7501 atagaggaca tctttccaac gaagacggtg cacttgtcat gactgatgtg atcggtaatc
     7561 ggaccaaacg aatctatctt ggccatctta gcaaggaaaa caatatgaaa gaacttgctc
     7621 atttaacaat ggaaaatgtt ttgaaagaaa aagattttgg cgttggacat gattttgaaa
     7681 tctatgatac agatccagat gaagcaactg agctattttc gatttaaaca gttcaatcaa
     7741 taaaaatata aaaagcagaa gataaaatca atcagggttg gttttatctt ctatttttat
     7801 ttttttagca tattaaaaaa ataaccgtat tatcgactga ctacactgat gtgctgcttt
     7861 tcatgtttct catccagtat ctcatctact aatgcaatcg cgtaatctgc catgctgatc
     7921 gtactgtcgc cagcagcgtt tctttgtaaa taatcatcac ttaacaaata agtacctgta
     7981 cgtttgccat gtggatcaaa taaagaagct ggactgatat aagtccaatg tagattttta
     8041 gattgtttca attttaacaa tccttcgtac atattgaaag ctgttggata gaagggtgca
     8101 tttttaggta cttggtcaat catacgagtc gtcttttctg tatctaagaa taacgaagag
     8161 gcacccccaa cgacaattaa gcgtgtatcg gttccttcaa gcatctcaat caaatgggac
     8221 aaagaagttt gatgcatttc ttcttttcct ttgggagcgt tgaaagcatc aacgacaaca
     8281 tcaaaagatg caagatcagt agttgtcaac tcaaataaat ccttttgtat aaacggaaca
     8341 tctgatggca atttttctgg atgacgcacg attgccgtca cgtctaaatc tctggacaat
     8401 gcttcgtcta aaataaatga acctgcatgg ccagtagctc caatgagtgc aattttcata
     8461 aaaaacctcc ttttttattc ctgtccattg taagcagttg ctgaatattc gtcaaagaat
     8521 ccgatttttg aaaagctcag tgcgcattcc tttcatggtt cgtgatcatt gggtatagtt
     8581 aaattaagaa aactgattga taaaaataga agttgaagga gataagaaat gaaagagtgg
     8641 ttagatcgtg cctttttacc aatgataaca tctgttgtga atcttagacc cttaactgct
     8701 ttgcgtaatg gaatgactta cacgatccca ataattattg ttggctcgct gtttttctta
     8761 tttgctcatt ttcctgtgga ttacatcgct cagtggatag acaaaacagg attttctatg
     8821 tattttacac aagtatacca ggctacattt gatgtgatag ccttttggat cgtttttgcc
     8881 attgcatacg cttatgcaaa agaagaagac atcgatcgct taccagtcgg cataacagcc
     8941 ttgtctgctt atctactgct tattcagcca ctaaatactc agatagatac tgtctggaca
     9001 ggtgctgaag ggatactagg agcagttaca actgggctca tcatcggatg gggctatgca
     9061 cgtttagtaa gacttgcgaa agggtggaag caaagagaga agatacctga aaatgtttgg
     9121 cagtctttta cttcattgat tccaatcatt gttatagtca cttttacgct tatcggttca
     9181 gcggtttttc aacagttgtt cagaatgact gttgttcaag gagtatggac atatgtccag
     9241 cttcccattc aatcgttcat agacacgttg tttggtgtgc ttttattagg tttttttgtt
     9301 ccgtttttat ggttatttgg tcttcatgga tctgcgatgg tcaatgggtt ggttagtccc
     9361 gtcttgcaag cgaattcatt agcgaatgca gaaatcttag cctcaggaca agagttgacg
     9421 gtggcaaatg gcggacatat cgttactcag caatttctcg atcagttcat gacggttacg
     9481 ggtgctggat tgacgttagg ggctgtattt tttatgacgg tttttgcgaa atcgaagaaa
     9541 tacagagaat taggaaatct tgctctttta ccagcctttt tcaacatcaa tgaatcaatt
     9601 attttttcca caccgatcgt gatgaacccg atgatggctg ttccttttat tttcgcaccg
     9661 gtcgtttcag gattgattac ctattccgct ttatattttg gattcgttcc tttatttaca
     9721 gcagtccaag tcccttggac aacaccgccg atcctctcgg gtttcttagt aggcggagtg
     9781 cctgcagcga ttttacaagg tatcgtgttg tcaattagtt ttttcattta tttcccattt
     9841 ttgaaaaaaa tagattctgc aaactgcaaa aaggaaagac agacaaaaaa tgatggagca
     9901 gcagaaaaga tgaacgacta aaaaacaaaa atactcctgt cgctttagat tgggaaaatc
     9961 accaatctag gatgacagga gtatttatag tcatgtttat actagccctt tttggacagc
    10021 taattgaaca agaacaacta atgtgttcat tcctacgtgt gtgatcatcg atgtccagat
    10081 ccgaccagtt gctttgtact ctaggctgaa gaagaaacct aggaaaaagt agattagcag
    10141 atgaccatca ttatgagcaa acgcaaacag caaagagctg atcactgctc cgacccaaaa
    10201 atttgaatat cgactgatga tccccagtat actgcggcgg aatacgaact cttccatgat
    10261 gggtccagca acagttgtcg ccaaaataaa agcgggtgct tccatgatca tctggatgat
    10321 attttgtgta ttctcggaag gggttgcttt gccaaacaat acagattcta acatgacagc
    10381 gatgctttgc agaatcaatg cgacaaagat tccaaccaat ccataaataa caatctttgg
    10441 agcagaagct ttttttaccg ctgattcgat cgctaagggt tcacgttgct taaaataaaa
    10501 aatagctagg acaacggcgc ctagtatata catgactgca gttgctgtga tcaattcaga
    10561 cgtagatttt acaagtccta tcgaagctag gatcaagggt gagataaaaa ttagaccata
    10621 gcaaaaaatg ctgaggaagc tatatttttt taaagacatg taattcctcc ttttaaggga
    10681 taacaagcat gcaaggcaag cttatatcga ttgatttcaa ttatatcata atttcaataa
    10741 gcagctgtca gaataaaatt tcttttcttt gatttaaaag cttgcaaaaa agagggagaa
    10801 tgagtattat taaaaatgta ggttagcact cgaaggttaa gagtgctaac agattaaaaa
    10861 aagagttatc ggagggattt atcgtgttaa aaccattagg tgatcgcgtc attatcgaag
    10921 tcgcaaaaga agaagaaaaa actgtcggag gaatcgtttt agcttctgct gctaaagaga
    10981 aaccccaaac tgggacagtt gttgcagtcg gtgaaggccg tttgttagaa aacggtgaaa
    11041 aagttcctgc cgctgtaaaa gcaggcgacc aagttatgtt cgaaaaatac gccggtacag
    11101 aagtaaaata cgaaggaaaa gaatatctga tcgtcgcagg aaaagatatc atggcgattg
    11161 ttgagtaaat ttggaagata aaaaaataat caaaaataat caatgaggtg aatcaatcat
    11221 ggcaaaagaa ttgaaatttg cagaagacgc acgcgcagct atgttacgcg gggtagataa
    11281 attagcagat acagtgaaag taacattagg acctaaaggc cgaaatgtcg tactagaaaa
    11341 atcttacggc tctccattga tcacaaatga tggtgtgacg atcgcaaaag aaatcgaatt
    11401 agaagatcat tttgaaaaca tgggtgcaaa acttgtatca gaagtagcat caaaaacaaa
    11461 tgatattgca ggagacggta caacgacagc aactgttctg acacaagcaa tcgttcgcga
    11521 aggtttaaaa aacgtaactg caggtgctaa tcctctaggc attcgtcgcg ggatcgaatt
    11581 ggcaacaaaa gcagcagtcg aagaattgca taatatctca actgttgttg attcaaaaga
    11641 agccattgca caagtagcag ctgtttcttc gggttctgat aaagttggac atttgattgc
    11701 tgatgcaatg gaaaaagttg gaaacgacgg tgtcatcaca atcgaagaat caaaagggat
    11761 cgaaacagaa ctagatgttg tagaaggtat gcagtttgat cgtggttact tatcacaata
    11821 tatggtaaca gataacgaca aaatggaagc tgttctagaa aacccatata tcttgatcac
    11881 agacaaaaaa atctctaaca tccaagatat tctgccattg ttagaacaaa tcttgcaaca
    11941 atcacgtcca ttgttgatta ttgctgacga tgtagatggt gaagcattgc caactcttgt
    12001 attgaacaaa atccgtggaa cattcaacgt agtagctgta aaagctcctg gtttcggcga
    12061 tcgtcgtaaa gcaatgcttg aagatatcgc tattttgaca ggtggtacag taattactga
    12121 cgatctaggt ttagaattga aagatgtaac aatcgaaaac ttaggaaatg cttctaaagt
    12181 tgttgtagat aaagacaata caacgatcgt agaaggttct ggagaaaaag aagcaatcga
    12241 agctcgtgtg caattgatca aaaaccaaat tgctgaaaca acttctgatt ttgaccgcga
    12301 aaaattacaa gaacgcttag ctaaattagc aggtggtgta gctgttgtta aagttggtgc
    12361 agctactgaa acagaattga aagaattaaa attacgcatt gaagatgcat tgaatgctac
    12421 acgtgccgca gtagaagaag gaatggtctc aggtggtggt acagctctag tgaacgttat
    12481 cagcaaagtt tctgctgtag aagcagaagg agacgtggca acaggtatca agatcgttgt
    12541 tcgtgcttta gaagaaccaa ttcgtcaaat cgctgaaaac gctggttatg aaggatcagt
    12601 gattgttgat aaattgaaga acgtggaact aggcactggt ttcaatgctg ctactggaga
    12661 atgggtaaac atggttgaag caggtatcgt agacccaact aaagtaacac gttctgcctt
    12721 gcaaaatgcc gcttccgttt ctgccttgtt attaacgaca gaagcagtcg ttgcagataa
    12781 accagaacca gcagcgccag cagctcctgc aatggatcca tcaatgatgg gcggtatgat
    12841 gtaagaaaaa gcaacttgct tatctacaac tgatcattag tgaaagacag ataaaaagag
    12901 gctggaacag aagcgtttaa ctccaagaaa taagaagaaa ttcacggaaa ttgcttttca
    12961 aatttttgtg aatttcagct tatttccgaa ggagttgctt ctgcttccgc tgtttatacg
    13021 tgtttagagc gtgagacaaa agtgttctt
//
LOCUS       DAFBVQ010000072        12734 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.075, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000072 DAFBVQ010000000
VERSION     DAFBVQ010000072.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12734)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12734)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12734
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.075"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(10..159)
                     /locus_tag="LLC22_002356"
     CDS             complement(10..159)
                     /locus_tag="LLC22_002356"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435605.1"
                     /translation="MTFYNKDIQYRVTLDTDLNLFVVFDKENTNHVATGVTIEQAVQE
                     LKKSA"
     gene            555..755
                     /locus_tag="LLC22_002357"
     CDS             555..755
                     /locus_tag="LLC22_002357"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5435606.1"
                     /translation="MNNGTVKWFNADKGFGFITGEDGNDVFAHFSAIQGDGFKTLEEG
                     QAVSYDVEDGQRGPQATNIVKA"
     gene            1323..1886
                     /locus_tag="LLC22_002358"
     CDS             1323..1886
                     /locus_tag="LLC22_002358"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002350857.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435607.1"
                     /translation="MLYIKKGIIVISFFKEYLEIINFRLKTKKESVIILVYFQGGNLM
                     IKKLFLLSILTLAMAGCSDSGLATELITKSTEATTEELKCGNDHSDYRGLNRRCMGIL
                     GRSNCKHRCSNRRRCRRSNRKIKRKIKRSNLCCASYTDVEDAVLLNHVRRCSFMSREV
                     GDEPKLEYAFSFAREDEDNPKTYDILA"
     gene            complement(1947..2291)
                     /locus_tag="LLC22_002359"
     CDS             complement(1947..2291)
                     /locus_tag="LLC22_002359"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348902.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435608.1"
                     /translation="MISKLPRQQLLGQHRECCALRGNGWGKKHATVDYVFHYSPYRLF
                     QYHQLVMDEMEKRGYSPAPEWKNPMYRGKSCEAFFDLPTVERNVPIYPEHDEVYLAEC
                     LANLEQKGIYLT"
     gene            complement(2388..2633)
                     /locus_tag="LLC22_002360"
     CDS             complement(2388..2633)
                     /locus_tag="LLC22_002360"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5435609.1"
                     /translation="MSIEEAILLDTLRCRLNFLRTGRSLSQVAVSSALSIPLFKYRKY
                     EEGEEIPSIIELIYIADFYDISVDYLIGRSETASKLK"
     gene            complement(2703..2957)
                     /locus_tag="LLC22_002361"
     CDS             complement(2703..2957)
                     /locus_tag="LLC22_002361"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435610.1"
                     /translation="MITLVRVLFWVPAVALVASIVYLMNWNKERFYLAILTLPAIYFM
                     WKVFNYNYFEPDSVFIEELSGLVLSLLIVILYLIRLNKKH"
     gene            complement(3121..3444)
                     /locus_tag="LLC22_002362"
     CDS             complement(3121..3444)
                     /locus_tag="LLC22_002362"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314960.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435611.1"
                     /translation="MLGVIILPFIAILFDLVAAAAYFLQLNYQTSGILFIGMIFQGVI
                     TLLLLVMMLSYKGKRYARIQTKVFVKYVSIRYGIIILSFLVNAIVLFLYVLNYLDINP
                     LIFSR"
     gene            3631..3704
                     /locus_tag="LLC22_002363"
     tRNA            3631..3704
                     /locus_tag="LLC22_002363"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3665..3667,aa:Ile,seq:cat)
     gene            complement(4089..4586)
                     /locus_tag="LLC22_002364"
     CDS             complement(4089..4586)
                     /locus_tag="LLC22_002364"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327002.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine hydrolase"
                     /protein_id="HBK5435612.1"
                     /translation="MLVIIDMQNHILDPNSEFYIPESDQLAERIAQRLAKARQNNEYI
                     LFTRDIPVELKDKEEEREDLQLIPLLSPQENERVIKKYYFTIPPETLAEIQETLFESK
                     EEQKEIEVVGIETNLCVLSNLIGLQSAFPEADFFVDPMLVSSRKHGESALELLKDFNV
                     SIVES"
     gene            complement(4626..5435)
                     /locus_tag="LLC22_002365"
     CDS             complement(4626..5435)
                     /locus_tag="LLC22_002365"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5435613.1"
                     /translation="MKLAAIDLDGTLLDRNGKIPEENIQALRKFDENGGIVTVATGRN
                     SISAKDIFSELGIGGYLISSNGSLIAEMKDGKMAKVLRRSKIDSDTLRKAFFYAQEAK
                     ISIIASRETQDDQLTFDESNLVKDDPYYEHFNLQNHSFDQILNMLEDPSLSYLKLALT
                     DKSEEKLQKLQRDLQADGIQSVFSDPHFLEITPTGITKAHSLVFLADYLGIESSDIMA
                     FGDQENDIDMLNYSGLSIAMGNAQRQVKEIANQVTLTNEEAGVAYILKNFY"
     gene            5769..6626
                     /locus_tag="LLC22_002366"
     CDS             5769..6626
                     /locus_tag="LLC22_002366"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBK5435614.1"
                     /translation="MEKRYGVVPVVTASDENYAPYLSVMIATALENCNKTRRIKFYVI
                     DDGLSEYSKEGLEETVNKYSSNASIQFLTVEKDIYEDFLVSDHITTTAYLRISLPNLL
                     AKEDYKKVLYLDSDVLVLDDIVKLYDEPLNGKTIGAIIDPGQVKALERLGIDSDDLYF
                     NSGVMVIDIDQWNKKEITEKTIHYLSENGDRIIYHDQDALNAVLYEDWEQLHPKWNMQ
                     TSLIFERHPAPNEKYERQYKEGNEKPSIVHFTGHDKPWNTLKDHPYTNLYLKKLAHST
                     LTKVGEINE"
     gene            6619..7521
                     /locus_tag="LLC22_002367"
     CDS             6619..7521
                     /locus_tag="LLC22_002367"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycosyltransferase family 8 protein"
                     /protein_id="HBK5435615.1"
                     /translation="MNKKEIAVVASCNTKFVPHLAALFVSVLDNCNPSKFVRFYVIDD
                     DIDFESKQLLRFSVKNARMNSDVEFLKINKEFFTNVVISDRIPETAYYRIAIPELFRG
                     TEVERILYMDCDMIALQDISKLWRLDFGDSIVAAVEDAGFHQRLEKMKISAKSMRYFN
                     SGLMLINVKKWLDENITQKVLDFIEHNPEKLRFHDQDALNAILHDRWLPLHPRWNAQG
                     YIMAKAKKHPTAAGEREYEETRNNPYIIHFSGHVKPWSKDFEGPTKKYYEKYAGMTAF
                     RCVAKFPKYPKYAKVQPKTDVVVK"
     gene            7554..7904
                     /locus_tag="LLC22_002368"
     CDS             7554..7904
                     /locus_tag="LLC22_002368"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296672.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBK5435616.1"
                     /translation="MEITMSKNAVETLIEKVGENTKIALALINDSDPFLRDKGAFAKG
                     SFFQIIPFVSEFGEYATKIEHPLLDIYTSKLEQNYFGKRLNMDFNKQLDSFSLENEIA
                     VLDYNIKLKNCFFS"
     gene            7953..8876
                     /locus_tag="LLC22_002369"
     CDS             7953..8876
                     /locus_tag="LLC22_002369"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303839.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="magnesium transporter CorA family protein"
                     /protein_id="HBK5435617.1"
                     /translation="MDEEKNVIETDEKKYNWLVLDSAKPEEIEQAIEEFELPDDIFVG
                     TEYPEEVSRMERLYETKLEHPFSLVVINLDQSDNRIEKKLTPISFVLSDNLLITCIDR
                     KTEFVDRLLTKHGNHLNSFEKIITYTLLDIYTHYVKELREMKKRIDALDKAARKTTEN
                     EELYKQADLERDIVYIDHTLRDQRETMDQLWNSETFIKRLDDEQLLYDVHLRQRQTEK
                     MIEIYRDLLESIGDLFNGMMDNNLNHIMKYLDSAALIISVPALFAGIWGMNTGGLPGK
                     SSALGFILVVFGSLIAAVVLGYHLYRKDYTN"
     gene            8954..9847
                     /locus_tag="LLC22_002370"
     CDS             8954..9847
                     /locus_tag="LLC22_002370"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5435618.1"
                     /translation="MTEPKLIDPRNLYHTEKFPKQDQDTPALQQNMIPVPDCGEESYE
                     GNNQLENRRVLITGGDSGIGRAAAIAFAREGADIALQFFPGEEKDAEEVAKYVKVAGR
                     KIVLLPFDLRDEQAPKEIIDKAVSELGGLDTMVLNAGQQISCQSIAELPLEQVKDTFM
                     INIIAMFALVKEAVPHIPAGGAIVTTTSVQAFNPSEHLLDYAATKASIANFTIGLAKQ
                     LAPKGIRVNGVAPGPIWTPLQLDEGQPSDSIPEFGQQSLLERAGQPGELAPVYVFLAS
                     NKASYVTAQIYGVTGGEAINL"
     gene            9885..10448
                     /gene="amaP"
                     /locus_tag="LLC22_002371"
     CDS             9885..10448
                     /gene="amaP"
                     /locus_tag="LLC22_002371"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376597.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBK5435619.1"
                     /translation="MNKGVKTIGVIGTLLLLSVLLFAILLSATYPLPFQLEKFRFFSI
                     TNSYVQQYVFWLAVAFAILTIITLLVFLFYPKTIGNFLLKHGDGELTLDKKAIEGMVR
                     SHLHEDEFIHSPKVNVKATKNKIAVNVKGELKRTSALIGKTGTLMKEIENEVQHILGT
                     KEPVKVSVKYTGFEEPAKRSNDRKRVE"
     gene            10462..10650
                     /locus_tag="LLC22_002372"
     CDS             10462..10650
                     /locus_tag="LLC22_002372"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBK5435620.1"
                     /translation="MKELFSTYKLPIIFGVLGLILAVLWITVGFFKTLLILIMAAIGV
                     AIGFYLKQTKILDHYFKS"
     gene            10663..11565
                     /locus_tag="LLC22_002373"
     CDS             10663..11565
                     /locus_tag="LLC22_002373"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296679.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5435621.1"
                     /translation="MNNNNKNNNNKMNNQKPVSAHPDPTTPNQSNGVNDEKNKTAPVS
                     AHPDPVVPNVQQGVEEKKHDAEKHAPHHPGTPESKVPEQHDAIDPSKPVEEQKHPSDH
                     AKAQEKLSSDHTNGQGKLGSDHTNNQGKHDSEQEDSMRGELNYEDKVVQKIIGIAIEQ
                     VDGLLSANGGFFSNVAGKLVNTDNVTAGIETEVGKKQVAVDMDVIVEYGKDIEKIFEE
                     MQEVIGKEVKNMTHLEVIEVNANVVDIKTKEEFEKDQETVQDKVTDAAKKTGEFASNQ
                     TDKVKSAAGSGAQKVKENTEPRVQ"
     gene            11597..11839
                     /locus_tag="LLC22_002374"
     CDS             11597..11839
                     /locus_tag="LLC22_002374"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5435622.1"
                     /translation="MGFIWSLIVGGIIGAIAGAITNKGSSMGIIANVVAGLVGSALGQ
                     ALLGSWGPSIAGMAIVPSLIGAIILVLIVSFFARKL"
     gene            complement(12095..12466)
                     /locus_tag="LLC22_002375"
     CDS             complement(12095..12466)
                     /locus_tag="LLC22_002375"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339233.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435623.1"
                     /translation="MPFIVYFFLSLLVIYIPLPTFFLLVNRLAEQHDTIAALTKLCLL
                     LFVCLDYFTSYYWLKQTRVKKRYYFFLVFFNLFEFLIHCFLLHQYHTIHLWIIWVFKV
                     VVLFCMFTFPISRKFREALFY"
BASE COUNT         4510 a         2130 c         2393 g         3701 t
ORIGIN      
        1 ttccactcct tatgcagatt tttttaattc ttgcactgct tgttcgatcg taacacctgt
       61 cgctacatga ttggtatttt ctttgtcaaa aacgacaaat agattcaaat ctgtatccaa
      121 ggttactcga tattgtatat ctttgttata gaatgtcata gccattctcc tttctttaaa
      181 tacttgctga aaggcaacga acgcgttgat aacgaaattc catttataag tataccacca
      241 attgaaaggt tttcatagtt aagaaatttt aaagtcaaaa gttgcagata aaagcaaata
      301 aacaagaaaa caaaaagtga atcaatcgcg gttattcaac tttttcttcg attcgaagac
      361 aatagaagac aatgaatttt atatttcatt gcattatcct tgtgttatta gaaaaagcat
      421 gatatattaa atgagtaatc tattttgaaa cgtaatttga gcgatatatc tacatagata
      481 aaactccttt tgcctatcaa atatttattg caacgaaaaa acgtacattg atacgtatca
      541 ggaggaattt atttatgaat aacggtacag taaaatggtt caacgcagac aaaggttttg
      601 gctttatcac tggtgaagat ggaaatgatg tatttgcaca tttttcagct atccaaggtg
      661 acggcttcaa aactttagaa gaaggccaag cagtgtctta cgatgttgaa gatggtcaac
      721 gtggccctca agcaacaaac attgttaaag cttaataaaa attgactttt aaccgtcttt
      781 tcgaaagaaa agacggtttt tttgtacgaa aaaattcatt ggtcgttgaa tgggctgaat
      841 agtagtgtat aaaacaattt tgtggagcgt gaagctttta tggtagagga aaatacgaat
      901 aaagtgatgt tgataaaaag attcctatct tgaatatgaa tcgagatgtc ttgaaaatga
      961 atgagtttga ccaatcatta tcctatcgaa atttacagtt tcgttcgatt ggtctgtcaa
     1021 ttaatgaaaa agtaaaaaag aatatgttct aggaagaggg cggcacatct aaatttttaa
     1081 gtaacggaca gttcaaatat caagcattga aagaggctat cctactgttt gaaggaatac
     1141 gaatatataa aaacgacaaa gaggaaaaag tagttcatta aatcccttca agtgatgaaa
     1201 gaatgagatc taataaaacc tgatctttca tctgtttttt taataacgta ataatttttt
     1261 tattttttgt gctttcgccg ttattgtaga gtgatttagc attcttattt ttaaaaataa
     1321 ctgtgttata tattaaaaaa ggcataatag ttataagctt ttttaaagaa tatttagaaa
     1381 ttattaattt tcgtctgaaa acaaaaaaag aaagcgttat tattttagtc tattttcagg
     1441 gggggaacct tatgataaaa aaactatttt tactatcaat attaacgcta gcaatggcag
     1501 gttgttctga ctctggctta gcaactgaac tgatcacaaa atcaactgaa gccacgacag
     1561 aggagttaaa atgtggaaac gatcacagtg actacagagg cttaaatcga cgatgcatgg
     1621 gaatattagg cagaagcaat tgtaagcatc gatgtagtaa tcgaagaagg tgtagaagaa
     1681 gcaacagaaa aatcaaaaga aagatcaaaa gaagcaatct gtgctgtgca tcgtatacag
     1741 acgtcgaaga tgcggtactt ttaaaccacg tcaggagatg ttcatttatg tctagggaag
     1801 ttggcgatga accaaaacta gagtacgctt ttagttttgc acgtgaggat gaagataacc
     1861 ctaaaactta cgacatttta gcttgatcta agatggttaa agctttttaa tgaagtaaga
     1921 ggagatagaa ggcttttcta gttatattag gtaagataaa ttcctttttg ctccaaattt
     1981 gctaaacatt ctgctagata aacttcatcg tgttccggat aaatcggcac gttgcgctct
     2041 acagtaggta aatcaaaaaa tgcttcgcat gatttgccac gatacatagg atttttccac
     2101 tctggtgctg ggctgtaacc acgtttttcc atttcatcca tgacaagctg atgatattgg
     2161 aataatctat aaggagaata gtgaaaaaca taatccacag tagcatgttt ctttccccag
     2221 ccatttcctc ttaatgcaca gcattcccga tgttgtccta aaagctgttg acgaggaagc
     2281 tttgaaatca atttttcatg ccataatcac atagaaatgt ctcctttata tatagattgt
     2341 taaccttaga cgttaaatga aaaaaccagc accaaggctg gaaaaaatca cttcagtttg
     2401 cttgctgttt ctgagcgacc aattaggtaa tcaacggaaa tatcgtaaaa gtcagcgata
     2461 tagattaatt caatgatgct tggaatttct tctccttctt cgtacttacg atatttgaat
     2521 aaaggaatac ttaacgcgct agaaacagct acttgagata aagatcggcc agttcttaag
     2581 aaattcagac gacaacgtaa agtatccagt aaaatagctt cttcgatact catttaatca
     2641 cctttcatta tagtagaata gttataatga ctatagaaag ctacacatgc aatcaatagt
     2701 actcaatgtt ttttatttaa acgtatcaaa taaagaatga cgatcaataa agacaaaacc
     2761 agtcctgata attcttctat aaaaacacta tcgggttcaa agtagttgta attaaaaact
     2821 ttccacataa agtagatagc cggaagagtc aaaatagcta aataaaaccg ttctttgttc
     2881 caattcataa gataaacaat acttgcgacc agtgcgaccg caggcaccca aaacaaaact
     2941 ctcaccaacg taatcatgta acggactcct caacgattca tataataaaa gataacatgt
     3001 tattgcatac atcacaaatg aaatgctagg aaaataaaag aagaatagat caatgaaaaa
     3061 tgaaaaagca gaacagtttt ctgctgataa gcaggaactg ttccgctgaa tgtgtcttat
     3121 ctatcgagaa aaaatcaatg gattgatatc taagtaattc aatacatata aaaagaggac
     3181 gatcgcattc actaaaaagg aaagaatgat gatcccatag cgaatggaaa catatttaac
     3241 aaatactttt gtttgaatac gggcatatct ttttccttta tagctgagca tcatgacaag
     3301 aagcaaaagg gtaatcacac cttgaaaaat cattccaata aacagaattc ctgaggtttg
     3361 ataatttaat tggagaaaat aagctgctgc cgcaactaaa tcgaataaaa tcgcaataaa
     3421 tggcaaaata atcactccta acattgagaa taaataaaag aataacattt tttctaaaat
     3481 aagcaaataa aaattaaagt aacaaaatag ttatgacaca agtaaaagaa ataagaataa
     3541 caatattatt ttacttatat tttgaaactt gtgagagttt gtcattcgtg ctatagttga
     3601 aaagtaacaa aaataaattt tatttatgat gtacctttag ctcagttggt tagagcagac
     3661 ggctcataac cgtccggtcg taggttcgag tcctacaagg tacataagag gttgtgaaaa
     3721 agctgccctg catcaagtaa taagaacagc caagtaaaaa cagcttctta tgtttttact
     3781 tggctgttct tattactgca gatgcaagct tttgaatacc gtttaaggaa gaggttgtga
     3841 aatcagcgtt ttgacctgag tattagctta acaaacggaa aaatagttcc tcatattttg
     3901 ccgtttgtta agctaatacc gagggtcagc tgattgaaca ccatttaaga aagaggtcgt
     3961 gagcctgccg tttcactctg tgtcataaaa aagccaatct actttgatag aaaaagcacg
     4021 taggactaaa acagttctgc gtgctttttt tattgtgtgt taaatatcgt aaatgaagat
     4081 agatattttt atgattcgac gatagagacg ttgaaatctt tcaacagctc taaagcggat
     4141 tctccgtgtt ttctactgga gactaacatt ggatcaacaa aaaagtctgc ttcaggaaaa
     4201 gcactctgca ggcctatcag attagagagt acacacaagt ttgtttcaat cccgactact
     4261 tcgatctctt tttgttcttc tttgctttca aataaagttt cctggatttc agctaaagtt
     4321 tcaggtggaa tcgtaaagta atacttttta atcactcgtt cattttcttg tggagaaaga
     4381 agagggatca attgcaaatc ttctcgttct tcttctttgt ccttcagttc aactggtata
     4441 tcccgtgtga agagaatata ttcattattt tggcgtgctt tagctaatct ttgagcaata
     4501 cgttctgcca attgatctga ctctggaata taaaattcgc tgtttggatc aagaatatga
     4561 ttttgcatat caataataac taacattttc tttcctccta cattcatatc gtcattttat
     4621 tctttttaat agaagttttt taaaatataa gcaacaccag cttcttcatt cgtcagtgtt
     4681 acttggtttg caatttcttt tacttgtcgc tgtgcattcc ccatcgcaat actcaacccg
     4741 ctgtaattca acatatcaat gtcgttttct tgatcgccaa aagccatgat gtcactcgat
     4801 tcgattccaa ggtaatccgc cagaaaaaca agtgaatgag ctttagtgat acctgtaggc
     4861 gtgatttcta agaaatgcgg atcagagaat actgattgga taccatctgc ttgcagatct
     4921 ctttgtagct tctgtagttt ttcttcactc ttatctgtta atgctaattt aagatagcta
     4981 agagaaggat cttccaacat atttaaaatt tgatcaaaag aatggttctg taaattgaaa
     5041 tgttcataat aagggtcatc tttgactaga tttgattcat cgaatgtcag ctgatcatct
     5101 tgggtttctc ggctagcaat gatggatatt ttcgcttctt gagcatagaa gaaggctttt
     5161 ctcagtgtat cgctatctat ttttgaacgt ctgagaactt tcgccatttt tccatccttc
     5221 atttcagcaa tcagtgaacc attggaagaa atcaaatagc caccgattcc taattcggaa
     5281 aaaatatctt tagcagaaat gctgttcctt ccggtagcga cggttacgat tccgccattt
     5341 tcatcaaatt tccgaagtgc ttggatattt tcttctggta tctttccatt tcgatcaagc
     5401 aaggtaccgt ctaaatcaat cgctgctagt ttcattttat cttcctactt tctttttaca
     5461 tatctatttt cctgttacct taagattaaa tgagaattta aaaaaatgaa actaacttgc
     5521 tttgtcatta tgaatttttt caaaaaacat tcttaagaaa aaggtggcta tatatagtag
     5581 tttttggtca atacctttga ataaaaagcc atgaaaaacg aatagttagc gcttaccgat
     5641 gcgttttgtg ataaaaaaat tttaaaatat tcaatgaaaa caaagcatat attttgcttt
     5701 aaaaccaaat gaggaatatt ctagatgtag aacaggttag aaaaagatta gaaaaaggag
     5761 tgattttgat ggagaagaga tacggcgtag ttcctgtggt aactgcttca gacgaaaatt
     5821 atgctcctta cttgagcgtg atgatcgcaa ctgcattaga aaattgcaat aaaacaagac
     5881 gcataaaatt ttatgtgatt gacgatggtc tatcagaata tagtaaagaa ggattggaag
     5941 aaacggtaaa taaatattca agtaatgcaa gtatccaatt cctgacagtg gaaaaagata
     6001 tctacgaaga cttcctagtc agtgaccata tcacaactac cgcttactta agaatttctt
     6061 taccaaactt attagctaaa gaggattata agaaagtcct ttacttagat tcagatgtgt
     6121 tagtactaga cgatatcgta aaactatatg atgagccgtt aaatggaaaa acaatcggcg
     6181 ctattatcga tccaggccaa gtgaaagctt tggaaagatt aggaatcgat tccgatgact
     6241 tgtacttcaa ttcaggagtg atggtgattg acattgatca atggaataaa aaagaaatta
     6301 cagaaaaaac tatccattac ctcagtgaaa atggcgatcg aatcatctat cacgaccaag
     6361 atgctttgaa tgctgtactt tatgaagatt gggaacaact tcatccaaaa tggaacatgc
     6421 agacttcgct gatttttgaa cgtcatccag caccaaatga aaaatatgaa cgtcagtata
     6481 aagaaggaaa tgaaaaacct tcgatcgttc actttacagg acatgataaa ccttggaata
     6541 cgttgaaaga tcatccgtat accaatttat acttaaaaaa attagcacac agtactctaa
     6601 cgaaagtagg cgagatcaat gaataaaaaa gaaatagcag tagtcgcaag ttgtaacaca
     6661 aaattcgtac cacatttagc tgcattattt gtctcagtat tagataattg caacccgtct
     6721 aaatttgttc ggttctatgt gattgacgat gatatcgatt ttgaaagtaa acagctttta
     6781 cgcttctcag tgaaaaacgc acgaatgaac tcagatgtgg aattcttgaa aatcaataaa
     6841 gaattcttta caaatgtggt aatcagcgat cgtattccag aaacagctta ttatcgtatt
     6901 gcgattccgg aattgttccg cggcacagaa gttgaacgta tcttatatat ggattgcgac
     6961 atgatcgctt tacaagatat ctctaaatta tggcgtcttg acttcggtga ttcaatcgta
     7021 gcagctgttg aagacgctgg gttccatcaa cgactggaaa aaatgaaaat ttcagctaaa
     7081 tcaatgcgtt atttcaactc aggtttgatg ctgatcaatg tgaaaaaatg gttagatgaa
     7141 aatattacgc aaaaagtatt agatttcatc gaacataatc cagaaaaatt acgattccat
     7201 gaccaagatg cattaaatgc tatcttacat gaccgttggt taccacttca tccgcgttgg
     7261 aatgcacaag gctatatcat ggcaaaagca aaaaaacatc caacagcagc aggtgaacgt
     7321 gaatacgaag aaactcgcaa caatccttac attatccatt tttcaggaca tgtgaaaccg
     7381 tggagcaagg attttgaagg gccaacgaag aaatattacg aaaaatatgc agggatgacg
     7441 gctttccgtt gtgtagctaa attccctaaa tatccaaaat atgcaaaagt tcaaccaaaa
     7501 acagatgtag ttgttaaata atagaagaca acaactgaag agggggagta ggaatggaaa
     7561 ttacaatgtc taaaaatgca gtagagacgt taattgaaaa ggttggggaa aatacaaaaa
     7621 tcgcactcgc gcttatcaat gattccgatc catttctaag ggacaaaggt gcttttgcaa
     7681 aaggcagctt ttttcaaatc attccttttg tttcggaatt tggagaatat gcgactaaaa
     7741 tcgagcatcc attattggac atctatacat ctaaattaga gcaaaattat ttcggtaaac
     7801 gattgaacat ggacttcaac aaacagcttg acagcttttc attagaaaat gaaatcgcag
     7861 tactcgatta taatatcaaa ttaaagaact gcttcttcag ctaatagttt cgagaaagtc
     7921 caaaaaggag gtatacattg agatactact ttgtggatga agaaaagaat gtaatagaaa
     7981 cagatgaaaa aaaatataat tggctcgtac ttgatagtgc aaagcccgaa gagattgagc
     8041 aagcaatcga agaattcgag cttcctgatg atattttcgt aggaaccgaa tatccggaag
     8101 aagtttctcg gatggagcgc ctttatgaga cgaaactaga gcatccattt tctttggtag
     8161 tgattaatct agatcagtca gataatcgta tcgaaaaaaa attaacgcca atatcttttg
     8221 tactttccga taatctcttg attacttgta tcgatagaaa aaccgaattt gtggatcggc
     8281 tgctgacaaa gcatggaaat catttaaact cgtttgaaaa gatcatcacg tatacattat
     8341 tagatattta cacccattac gtgaaagaac taagagagat gaaaaagcga attgacgctt
     8401 tggataaagc agctcgtaaa acaacggaaa atgaagaact gtataaacag gcagatcttg
     8461 aaagagacat cgtatatatc gatcatacct taagagatca acgggaaaca atggatcaat
     8521 tatggaattc tgaaactttc atcaaacgtt tagacgatga acagctactc tatgatgtcc
     8581 atttgagaca gcgacaaaca gaaaaaatga tcgagatcta tcgagattta ttagagagta
     8641 ttggtgatct attcaacggg atgatggaca ataatctaaa tcatatcatg aaatatctag
     8701 attcagctgc attaatcatt tccgttccgg cgttgttcgc agggatttgg ggaatgaata
     8761 caggaggatt accgggtaaa agttctgctc taggctttat actcgtagtc tttggctctt
     8821 tgatagcagc agtagtttta ggttaccatt tataccggaa agattataca aattaaagaa
     8881 tctatttaaa acaggtatca aacaaagaaa tttgttttgg caatacaatt taaaaactag
     8941 gaggaataca gcaatgacag aaccaaaatt aatcgacccg cgaaacttgt accatacgga
     9001 gaaatttcct aaacaagatc aggatacacc agctttacag cagaatatga ttcctgttcc
     9061 tgattgtgga gaagaatcct atgaaggcaa taatcaacta gaaaaccgcc gtgtactaat
     9121 cactggtgga gattcaggga tcggtcgtgc agcagcgatt gcatttgcta gagaaggggc
     9181 agatatcgct cttcaattct tcccaggaga agaaaaagat gcagaggaag tagcaaaata
     9241 cgtgaaagtt gcaggacgta agattgtctt actacctttt gatcttcgtg acgaacaagc
     9301 acctaaagaa atcatagata aagccgtgag tgaacttggc gggctagata cgatggtact
     9361 aaacgcagga cagcaaattt cttgtcagtc tattgctgag ttaccacttg agcaagtcaa
     9421 agacacattt atgataaaca tcatcgctat gtttgcttta gtgaaagaag ctgttccgca
     9481 tatcccagca ggaggagcaa tcgtaacaac aacttctgtt caagcattca atccaagcga
     9541 acatttatta gattacgcag caacaaaagc ttcaatcgct aactttacga tcggtttagc
     9601 aaaacagctt gcacctaaag gaatccgtgt aaatggtgta gcacctggtc caatctggac
     9661 accattacaa ctagacgaag gacaaccttc tgattcgatc cctgaatttg gtcagcaaag
     9721 tttactagaa cgtgcaggtc agccaggaga attagcacca gtttatgttt tcttagcatc
     9781 gaataaagca agttatgtta cagcccaaat ttacggagta actggtggag aagcgatcaa
     9841 cttataagaa gttgatcgtt tcacccctat gaggaggtgc gaaaatgaat aaaggtgtaa
     9901 aaacgatcgg agtgatcgga acattacttt tgctatctgt gcttttgttt gcgatactat
     9961 taagtgcaac ctatccattg ccttttcagc tagagaagtt tcgattcttt tccatcacta
    10021 attcatacgt gcaacaatat gtattttggc ttgccgttgc atttgctatt ttgacaatta
    10081 tcacgttact tgttttcctg ttttatccaa aaacaatcgg aaactttcta ctgaaacatg
    10141 gtgatgggga gttgacgttg gataaaaaag caattgaagg aatggttcgt tctcacttgc
    10201 atgaagatga attcatccat tcaccaaaag taaatgtcaa agcaacgaaa aacaagatcg
    10261 ccgtcaatgt aaaaggggag ttgaaacgaa cttcagcact cattggtaaa acaggaacat
    10321 tgatgaaaga aatcgaaaat gaagtacaac acatattggg aacaaaagag ccagtgaaag
    10381 tatcggtgaa atacacaggc tttgaagaac cagctaaacg aagcaatgac cgcaaacgag
    10441 tagaataggg ggggaccaaa aatgaaagaa ctattttcga catacaagct ccctatcatc
    10501 tttggggtac ttggattgat attagccgtt ttatggatca ccgtgggctt tttcaagacc
    10561 ttattgatct tgatcatggc agcgatcggc gtcgctatcg gtttttatct gaaacaaacg
    10621 aaaatcttag atcactattt taaatcttag gaggaaacat ccatgaataa caataacaaa
    10681 aataataaca ataaaatgaa caaccaaaaa ccagtgtctg cacatccaga cccaacgaca
    10741 ccaaaccaat caaatggtgt gaacgatgaa aagaacaaaa cagcaccagt atctgcacat
    10801 ccagatccag tagtccctaa cgttcaacaa ggagtagaag agaagaaaca tgatgcagaa
    10861 aagcatgcac ctcatcatcc aggaactcca gaatctaaag ttccagaaca acatgatgca
    10921 atcgatcctt ctaaacctgt ggaagagcaa aaacatcctt ctgaccatgc gaaagcacaa
    10981 gaaaaactta gttctgacca cacaaacgga caaggaaaac ttggttctga tcatacaaat
    11041 aaccaaggaa agcatgattc tgaacaggaa gattcaatgc gcggtgagct gaattatgaa
    11101 gataaagttg tgcaaaaaat catcggaatc gcaattgaac aagtagacgg tttattatct
    11161 gcaaacggtg gtttcttctc taatgtggca ggaaaacttg tgaatacaga taatgtaacg
    11221 gctgggatcg aaacagaagt cggtaaaaaa caagtagcag ttgatatgga tgtcattgtg
    11281 gaatatggca aagatatcga aaaaatcttt gaagaaatgc aagaagtaat cggcaaagaa
    11341 gtaaaaaata tgacacattt agaagtgatc gaagtcaacg ctaacgtagt ggacatcaaa
    11401 acaaaagaag aatttgaaaa agatcaagaa acggtgcaag acaaagtaac tgacgcagcg
    11461 aaaaaaaccg gtgaatttgc ttcgaatcaa acagataaag taaaatcagc agctggaagc
    11521 ggcgcacaaa aagtaaaaga aaatacagaa ccacgggttc agtaataagg aagtaaaaca
    11581 ttaggaggaa cgaaacatgg gatttatttg gtcacttatc gtcggaggaa ttatcggagc
    11641 aattgcagga gcaatcacga ataaaggttc ttcgatgggg attattgcaa atgtcgtagc
    11701 aggtttagtt ggatcagcac ttggtcaagc attattaggt tcttggggac caagtattgc
    11761 aggaatggca atcgtgccat cattgattgg tgccatcatt ttagtactaa tcgtatcatt
    11821 ctttgctcga aaactgtaaa aagactttta aaaagaggtc gtgaaaaagc tgttcttcat
    11881 caagtaataa gaacagccaa acaaaaatag cttctcatat ttttcatttg gttgggcata
    11941 ttatcgaaga tgcaagcttt tgaacactgt ttatacggaa taagaggctg tgacaagact
    12001 tttgtcacag cctcttattt atgcgggcaa attcccaatt agatttttaa aagtttttcc
    12061 ttaaatgtgt ctttattgat acagagaagc ttctttaata aaacaatgcc tccctaaatt
    12121 ttcttgagat aggaaaggtg aacatacaaa ataatacgac cactttgaaa acccagatga
    12181 tccacaaatg gatcgtatga tactgatgaa gtaaaaagca atggatcaga aactcaaaga
    12241 gattgaaaaa gacaaggaag aaataatatc tcttttttac tcttgtctgt tttagccaat
    12301 aatagctcgt aaagtaatct agacaaacaa atagaagtaa acaaagtttc gtaagagcag
    12361 caatcgtatc atgttgctct gctagacgat tgacgagcag gaaaaatgtt ggtaatggaa
    12421 tatagatcac gagtaatgaa agaaaaaagt aaacaataaa tggcatacta ttcctcctaa
    12481 ttgtgtgagt tcgccctcat tttaaaataa cgatatttgt ttgtgaagct ttttcgtgtc
    12541 gtaacaaatg ttatctaatg tatttttaaa taaataatca ttattatcaa aataatgtca
    12601 gactgtagac aaagtccatt ttatggatga tgtctacagt cttttctttt ataatagatt
    12661 tatgaaaacg aatgcaagga gtgatagcta tgatgtctaa aaacaatacg aatggtagaa
    12721 atcaatttgc gatg
//
LOCUS       DAFBVQ010000073        12717 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.076, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000073 DAFBVQ010000000
VERSION     DAFBVQ010000073.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 12717)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 12717)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..12717
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.076"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LLC22_002376"
     CDS             complement(85..264)
                     /gene="rpmF"
                     /locus_tag="LLC22_002376"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719637.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L32"
                     /protein_id="HBK5435624.1"
                     /translation="MAVPARRTSKAKKAKRRTHYKLTIKGLNECPNCGEMKKSHHVCA
                     NCGYYDGKDVMSKEA"
     gene            complement(322..891)
                     /locus_tag="LLC22_002377"
     CDS             complement(322..891)
                     /locus_tag="LLC22_002377"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF177 domain-containing protein"
                     /protein_id="HBK5435625.1"
                     /translation="MKWSLLELRKYQETPLTFHETLDLKAALMKRDNLILDVAPVEVE
                     GLVSVDKKGYIVHYTVQTTLTVPSTRSLEPVELPMDFSVDEVFMTEEQFQSRDEQMSA
                     DEILLIEGPLLNLAESIEDNILLAIPMRVLTKEEEAATELPKGNDWEVVSEEEYQRRK
                     MEEAENKIDPRLAKLSELFDSKSKDDDNK"
     gene            1077..1979
                     /locus_tag="LLC22_002378"
     CDS             1077..1979
                     /locus_tag="LLC22_002378"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344100.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5435626.1"
                     /translation="MNTKDIEYYVQIVKQKNFTKVANYFRVSQPTITYALQRLEKEFD
                     TVLITRDRSHHELIVTPSGKQLFLHAQTILQEISTARAEITQLQKKKLRFGMPPIIGN
                     EYFPKLSSYFIKHELMNQIEITDGGSRDLYGMIRQGRIDLAVLGSTQPIVDQYLETEL
                     LLDKRFMIVVPPTHPLSKQDTVSFKDIADEQFVLLNEHYVHPAAFTKLSKQTHTHPKV
                     VYQSNDLTILKSMVRENVGIGFLAEIAVHPEDHLVCLPLSDEVQPRFLISLAKRTQQI
                     VTPLQEQVVQVIHEFVTAQKNSSS"
     gene            complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LLC22_002379"
     CDS             complement(2014..3798)
                     /gene="pyk"
                     /locus_tag="LLC22_002379"
                     /EC_number="2.7.1.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003127858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyruvate kinase"
                     /protein_id="HBK5435627.1"
                     /translation="MKKTKIVSTLGPASNSVEIISQLIESGANVFRFNFSHGDHEEQL
                     SRMTMVREAVKKTGKDVGILLDTKGAEIRTTVQGTTEADFGRAGYIKFEVGDQTRISM
                     DPEHVGSKEKIAVTYPGLFDDVHVGGHILFDDGLIDMQIIEKDEANRELVVEVKNAGM
                     LGSRKGVNAPGVSISLPGITPKDADDIRFGLDNDIDFIAASFVRKAQDVLDIREILEE
                     KDMTHVQIFPKIESQEGIDNIDEIIKVSDGVMIARGDMGVEIPAELVPMVQKRIIKKC
                     NAAGIPVITATQMLESMQENPRPTRAEASDVANAVFDGTDATMLSGESANGDYPVEAV
                     STMARIDQEAENALSELGTFQLNEFDKTDVTETIGLSVARAAKNLGVKTIVAATESGY
                     TAKMISKYRPDADILAVTFDERTKRGLMLNWGVYPTVAEKPSTTDEMFELAAKKAVEL
                     GFASEGDLILITAGVPVGERGTTNVMKIQMIGSKLLEAQGVGQKSVVANAVIASSAEE
                     AVKKAKDGMVLVVPSTDKEYMPAIEKAAAVIVEEGGLTSHAAVVGIAQDIPVIVGAKG
                     ATTTITEGELITVDSRRGIVYRGETTAI"
     gene            complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LLC22_002380"
     CDS             complement(3872..4834)
                     /gene="pfkA"
                     /locus_tag="LLC22_002380"
                     /EC_number="2.7.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010746303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="6-phosphofructokinase"
                     /protein_id="HBK5435628.1"
                     /translation="MKRIGILTSGGDAPGMNAAVRAVVRKGIYEGLEVYGINYGFAGL
                     VAGDIRRLDVADVGDKIQRGGTFLYSARYPEFATEEGQLKGIEQLKKFGIEGLVVIGG
                     DGSYHGAMALTKRGFPAVGIPGTIDNDIPGTDFTIGFDTAINTVLESIDRIRDTATSH
                     VRTFVIEVMGRNAGDIALWSGVAGGADEIIIPEHDFDMASVAKKIQEGRDRGKKHCLI
                     ILAEGVMGGNEFAEKLSEFGDYHTRVSILGHVVRGGAPSARDRVLASKFGAYAVELLQ
                     EGKGGLCVGIHDNEIVASDIIDTLENNKHKPDLSLYDLNNSLSF"
     gene            complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LLC22_002381"
     CDS             complement(5002..8316)
                     /gene="dnaE"
                     /locus_tag="LLC22_002381"
                     /EC_number="2.7.7.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002319208.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA polymerase III subunit alpha"
                     /protein_id="HBK5435629.1"
                     /translation="MFFPQLYTITSYSLLQSTIRIREYVQEAKKQGYTSLAITDKDVL
                     YGAPEFYRICVEEGVQPIIGLHLSYTYEEKNYGLLAYAKDEIGYQQLMKLSSRKMIQE
                     KLELAEMTETDHLAFVVPANHSVSEAFNKEDNFFGHWQFLLENVFTRNFYIGLTENTP
                     DQLPEWYQYVIKENYSLCALHPIASLQQEELFALEVMKHIKEGSQIPLENLSASLPLT
                     ANVYLLSEQEMIKRFEKAGLSQAVIGAQRLAESISFEFQFHQKLLPHYPVPNGKQAGE
                     YLRELCYSQVERRITDYTKEYQERLDYELSVIHQMGFDDYFLIVWDVMAFAHRNKIVT
                     GAGRGSAAGSLVAYVLEITDVDPLEYDLLFERFLNPERFTMPDIDLDIPDNRREEVLN
                     YVREKYGQYHMAQIATFGTMAAKMVLRDAARVFGLSQSEANRWSKAIPNQLKITLTQA
                     YKTSHQLVELVQASEKNQLLFKTAVILEGLPRHVSTHAAGVVISDKNLLELVPLQRGS
                     DEAFLTQYTMNEVEAIGLLKMDFLGLRNLSIIDFTLKAVKRVEGYEIRLKEIPLNDAK
                     TLLLFQRGETSGVFQFESAGIRNVLRRLDPENIEDIAAVNALYRPGPMQNIDTFIARK
                     KGKEAIRYPDDSLIPILKNTYGVIVYQEQIMQIASTMAGFTLGQSDILRRAVSKKKKD
                     VLDEEKSHFVSGALQQGYSEKTAATVYEYIEKFANYGFNRSHAFAYSFVGFQMAYLKA
                     HHPGAFFTSLMNSVRHNTSKLKEYIAEARKNKLKLSSPSINQSNSSFELVNKEEIRFG
                     LTAIKGIRRDFVEDILNERKQNGPFQSVDQFLIRIDKRWLKLELLQSLTAVGVFDELS
                     PNRKQLMLDLEGKIQNIVYSGGSLDLLGIMALKEEEVADYTLEERLKLEEEYLGIYLS
                     GHPAEGFDRLRLAKQVQLITDIVPNQPVNLLVMIKEVREIRTKKGELMAFVEGTDSSG
                     EISVTVFPTLYRKYRNLFAVDRVIFVQGRSEISKYNQELQLIGESFADPNQLEAQYPS
                     QTCYLRITEEREDPEIMKQLQVIFQKHPGYIPVVMYHEKTQRKVVLSDAYWVDDSKSI
                     KGQLIYLLGEDNVVFK"
     gene            8547..8732
                     /locus_tag="LLC22_002382"
     CDS             8547..8732
                     /locus_tag="LLC22_002382"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290959.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjzD family protein"
                     /protein_id="HBK5435630.1"
                     /translation="MRYIVTLFWAVVLGQVVGYIGAALTSGTYDFTLTTIISFIAGVI
                     ILLIGAVAPRKETSAHS"
     gene            complement(8794..9990)
                     /locus_tag="LLC22_002383"
     CDS             complement(8794..9990)
                     /locus_tag="LLC22_002383"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629453.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux MFS transporter"
                     /protein_id="HBK5435631.1"
                     /translation="MEINWRKNLVIAWIGCFFTGASISLVMPFIPVYVEQLGTPKDQI
                     ELFSGLAISVTAFASAVVAPIWGNLADRKGRKLMMIRAAAGMTLTMGSLAFVPNAYWL
                     LIMRFWNGILSGYIPNATAMIASQAPREKSGWALGTLSTGAIAGNLIGPSMGGALAQW
                     FGMENVFLITGALLMITTVLTIFLVKEDFHPIEKKDLISTKEIFSKMDHLSILIGLFI
                     TTLILQIGITTISPILTLYIRELSGSTENILFVSGLIVSIAGVSAVFSSPKLGKLGDK
                     IGNQKVLIGGLILSFCCYLPMAFVTTPLQLGILRFILGFSTGALMPSVNTLISKITPQ
                     EGVSRIYSYNQMFSNFGQVLGPMLGSTVAHAYNYSAVFIVTSLFVLSNILLSLFNFRK
                     VLRSRL"
     gene            complement(10160..11596)
                     /locus_tag="LLC22_002384"
     CDS             complement(10160..11596)
                     /locus_tag="LLC22_002384"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290956.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NCS2 family permease"
                     /protein_id="HBK5435632.1"
                     /translation="MEKFFGLKKNNTNVSTEIMAGVTTFFAMSYILFVNPTILSASGM
                     PFQAVFLATIIASIIGTLVMGLFANVPYAQAPGMGLNAFFTFTVVFGLGYSWQQALAM
                     VFICGLINIFITVTNIRKMIIRAIPESLQHAIGGGIGIFVAYVGIKNAGFLSFSADQS
                     AISSSVVEGGKATNVTINGGIVPALANFDNAPILLAVIGLVLTAILVVKNVRGAILIG
                     IVATTVLGIFMGVVDLSSIDWQTNSLGNSFKELGTTFGAAFGSEGMQSLFSDSSKIPQ
                     VLMTIIAFSLSDTFDTIGTFIGTGRRTGIFSKEDEIALEDGRGFKTKMDKALFADAIA
                     TSVGAIFGTSNTTTYVESAAGIGAGGRTGLTSVVVAVLFALSSLFSPLIAIVPNQATA
                     PALILVGVMMMASFADIKWLDMEEALPAFFASIFMGLCYSISYGIAAGFIFYTIVKVI
                     KGKYNQVSVALWIVDILFIINFIILATI"
     gene            11889..12698
                     /locus_tag="LLC22_002385"
     CDS             11889..12698
                     /locus_tag="LLC22_002385"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295364.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5435633.1"
                     /translation="MNKKLIAIDLDGTTLNQDSMITSKTKETLKKAINAGHHVSIATG
                     RPFRMSHQFYQQLELTTPMVNFNGALVHIPNQHWDGERETLINREIAFEILSQKKQLN
                     LDFIAAENRDTFFIDSFDFFDEKIFASSRPGEKNLLSPKNLTTNPTSLLVRTDKRFAG
                     AVSAELTRQFGSYVDVRTWGGPTAILEIVSKGIQKAKGVQEIANYLSIDQKDVIAFGD
                     EHNDLELLDYAGWGVAMANGTDQLKGIANDVTPLSNQEDGLAVYLEKLLKL"
BASE COUNT         3794 a         2672 c         2245 g         4006 t
ORIGIN      
        1 attttttatt taccgactac aaaaaaataa acctcaaggc tccatggtta gccttgaggt
       61 tttacatttt ctaattaaaa tgtattaagc ttcttttgac attacgtcct taccatcata
      121 gtaaccacaa tttgcacata cgtgatggct ttttttcatt tcaccacagt ttggacattc
      181 gtttaaccct ttgattgtca atttgtagtg tgtacgacgt tttgcttttt tagcttttga
      241 tgttcttcta gctggtactg ccattttgct acacctcctt gtaaagtctt gtatctaaat
      301 tagacacaat atattccaat cttacttgtt atcgtcgtct tttgatttag aatcaaaaag
      361 ttcagatagt tttgcaagac gaggatcaat tttattctcg gcttcttcca tttttctgcg
      421 ctggtattct tcttcggaaa caacttccca atcattgcct tttggaagtt ctgttgctgc
      481 ttcctcttct tttgtcaata cccgcattgg aatcgccaat aagatgttgt cttcaatcga
      541 ctctgctaaa ttcaataatg gaccttcaat tagcaaaatc tcatctgcag acatttgttc
      601 atctctactt tggaattgtt cttctgtcat gaatacttcg tctacagaaa aatccatggg
      661 cagttcaaca ggttctagtg aacgtgttga aggaactgtc aaagtcgtct gcacagtgta
      721 atgaacgata tagcctttct tatcaactga gaccaaacct tcgacttcca ctggcgcaac
      781 atcaagtatt aaattgtctc gcttcatgag agcggctttc aagtcgagcg tctcatgaaa
      841 agttaacggt gtctcctggt attttctcaa ttccaataaa gaccatttca tttttcatca
      901 ctcctaagca acaaaagcaa ttatacaggg caaaaagcat gttgtcaatg aaattttctt
      961 gacaccttgc agttcataaa aaaacagaaa aatctttatt agaaagcctc tgtttgctat
     1021 catcctcaga atcatttaca ataatcatta ttccattaaa ggagcggatg atcttcatga
     1081 acacgaaaga tatcgaatac tatgtccaaa tcgtcaaaca aaaaaatttt acgaaagtgg
     1141 ctaattattt ccgtgtgagc caacctacta ttacatatgc attacaacgt cttgaaaaag
     1201 agtttgacac cgtacttatt acaagagatc gatcgcatca cgaattaatc gtcacgcctt
     1261 ctggaaagca gctgtttctc catgcacaaa ccattctcca agagatttct actgcaagag
     1321 ctgaaatcac tcagttgcaa aagaaaaagc ttcgttttgg catgcctcct attatcggca
     1381 atgaatactt tcctaaactg tcaagttact ttatcaagca tgaattgatg aatcaaattg
     1441 agattaccga tggaggctct cgggacttat acgggatgat ccgacaaggg aggatcgatt
     1501 tagctgtatt aggctcaaca cagccaatcg tggatcaata tttagaaaca gagttacttt
     1561 tggacaaacg tttcatgatc gtcgtgccac ctacacatcc tctttccaag caggatactg
     1621 tctctttcaa agatatagca gatgaacagt ttgtactatt gaacgaacat tatgtccacc
     1681 ccgcagcatt cactaagctt tctaaacaaa cacatactca tccaaaagtt gtttatcaaa
     1741 gcaatgactt gacgatttta aagagtatgg tccgagaaaa tgtgggtatc ggttttttgg
     1801 cagagattgc tgtccatcct gaagatcatt tagtttgcct ccctctttca gatgaagttc
     1861 agcctcgctt cttgatttca ttggcaaaac gaacacagca gatcgtcacg cctcttcaag
     1921 aacaagtagt ccaagttatc catgaattcg ttacagcaca aaaaaacagc tcttcgtaaa
     1981 agaagagctg tttttatttt ttattaagct aaattagata gctgttgttt cgccacggta
     2041 aacgatgccg cgacgtgaat caacggtaat caattcacct tctgtaattg ttgttgttgc
     2101 gcctttagca ccaacgatta caggaatatc ttgtgcaatt cctacaactg cagcgtgaga
     2161 agtcaatccg ccttcttcaa cgataacagc agctgctttt tcgattgcag gcatatattc
     2221 tttgtcagtt gatggtacaa ctagaaccat tccgtctttt gcttttttta cagcttcttc
     2281 agcagatgaa gcaataactg catttgcaac gacagatttt tgtccaacgc cttgagcttc
     2341 taataattta gaaccaatca tttgaatttt catcacgtta gttgttccgc gttcaccaac
     2401 tggtacacca gcagtgatca agattaaatc gccttctgat gcgaaaccta attcaacagc
     2461 ttttttagct gctagttcaa acatttcatc agttgttgat ggtttttcag caactgttgg
     2521 gtaaacgccc cagtttaaca tcaaaccacg ttttgtgcgt tcgtcaaaag taacagccaa
     2581 gatatctgca tctggacgat attttgaaat catttttgca gtgtatcctg attcagttgc
     2641 agcaacgatt gttttcacgc ctagattttt tgcagcacga gctacagata aaccgattgt
     2701 ttcagttaca tctgttttat cgaattcgtt caattggaat gtacctaatt ctgataatgc
     2761 attttcagct tcttggtcga tacgtgccat tgttgaaaca gcttcaactg ggtagtcccc
     2821 gtttgcagat tcaccagata gcattgttgc atctgtgcca tcaaatacag cgttagcaac
     2881 gtcagaagct tccgcacgtg ttggacgtgg gttttcttgc attgattcta acatttgtgt
     2941 agcagtgata actgggatac cagcagcatt acattttttg ataatgcgtt tttgaaccat
     3001 tggtactagt tcagctggga tttcaacacc catatctccg cgggcaatca taacaccgtc
     3061 agaaactttg atgatttcgt caatgttgtc gataccttct tgagattcga ttttagggaa
     3121 gatttgaaca tgagtcatgt ctttttcttc taagatttcg cggatatcta gaacgtcttg
     3181 tgctttacgt acaaaacttg cagcgataaa gtcgatatcg ttgtctaaac caaaacgaat
     3241 atcgtcagca tcttttggag taatacctgg caaactaata gaaacgcctg gtgcatttac
     3301 ccctttacgt gatcctagca tacctgcatt tttaacttct acgactaatt cacggtttgc
     3361 ttcgtctttt tcaatgattt gcatatcgat caaaccatca tcaaataaaa tgtgtccgcc
     3421 aacgtgaaca tcgtcaaata atcctgggta agtaaccgcg attttttctt ttgaacctac
     3481 atgttcagga tccatagaga tgcgtgtttg atctcctact tcaaatttga tgtatcctgc
     3541 acgaccaaaa tcagcttctg ttgtgccttg aacagttgta cggatttcag ctccttttgt
     3601 atctaaaaga ataccgacat cttttcctgt ctttttaact gcttcacgga ccatagtcat
     3661 acgtgataat tgttcttcat ggtcaccatg agaaaaatta aagcggaaga catttgcccc
     3721 agattcaatc aattgagaaa taatttctac tgagttactt gctggtccta atgtactaac
     3781 gattttggtt tttttcattt aaaaaactct cccattcaat tttgtttatt taaagctgta
     3841 cacagcttaa atagcttggt ttctttcact cttaaaatga aagtgaatta tttagatcat
     3901 atagtgataa gtctggttta tgtttgttgt tttcaagtgt atcaatgatg tcagacgcaa
     3961 cgatttcgtt gtcatggata ccgacacata atccaccttt tccttcttga agcaattcga
     4021 cagcgtaagc accgaattta cttgccaaca cgcggtcgcg tgcgcttggt gctccaccac
     4081 ggacaacgtg tcccaagata gatacacgtg tatgatagtc accaaattct gaaagtttct
     4141 cagcgaattc atttccgccc attacacctt cagccaagat gatcaagcaa tgtttcttcc
     4201 cgcgatcgcg gccttcttgg atttttttag caactgaagc catatcaaaa tcatgttctg
     4261 ggatgatgat ttcatccgct ccgccagcca cacctgacca taaagcgatg tctcctgcat
     4321 tgcgtcccat tacttcgata acgaatgtac gaacatgaga agtcgctgtg tcacgaatac
     4381 ggtcaattga ttctagtact gtattgattg ctgtatcaaa accgattgtg aaatcagtcc
     4441 caggaatatc attatcgatt gttccaggaa tacctactgc tgggaaaccg cgttttgtca
     4501 aagccattgc gccatgataa gagccgtctc ctccgataac cactagacct tcgattccga
     4561 attttttcaa ttgttcgatt ccttttaatt gaccttcttc agttgcaaat tctggataac
     4621 gtgcagaata caagaatgta ccaccacgtt ggatcttgtc acctacatct gccacatcaa
     4681 gacgacgaat atctccagca actaaaccgg caaaaccata attgatcccg tatacttcca
     4741 gtccttcgta aataccttta cgaacaacgg cacgaacagc tgcattcatt ccaggtgcgt
     4801 ctccgccact ggtcaaaatt ccgatgcgtt tcataataaa cattcacctc attaaaatac
     4861 tttatcctaa gtatgactta ggtttacaac catttttgcg ttaaccacga ctaacattct
     4921 aacattattt ttctcacttg tcttgattta cggataaaaa aatgaaaaaa aatgaaagca
     4981 agtagtattt tttaccgtaa gttatttgaa aaccacatta tcttcgccaa gcagataaat
     5041 aagttgcccc tttatactct tgctgtcatc cacccaataa gcatctgaca gaactacttt
     5101 tcgttgcgtt ttttcgtgat acataactac tggtatatat cctgggtgtt tctgaaaaat
     5161 cacttgtaat tgtttcatta tctcgggatc ttcccgttct tctgtaatac gcaaatagca
     5221 agtttgtgaa ggatactggg cttctaactg gttaggatca gcaaagcttt ctccaattag
     5281 ttgcagttcc tgattatatt tgctgatttc gctccgccct tgaacaaaga tcactcgatc
     5341 aacggcaaac aaattacgat atttacgata aagagttgga aaaactgtga cagaaatttc
     5401 tccactactg tcggttcctt caacaaaggc catcagttct cctttttttg tccgaatttc
     5461 tctaacttcc ttgatcatca ctaataaatt gactggttga ttagggacga tatctgtaat
     5521 cagctgaact tgtttagcta aacgaagacg atcaaaccct tctgcaggat gacctgacaa
     5581 ataaatacct aagtactcct cttccagctt caagcgttct tctagtgtat agtcagcgac
     5641 ttcttcttct tttaatgcca tgattcccag caagtcaaga cttccaccac tgtaaacgat
     5701 attttggatt tttccttcga gatcaagcat caattgtttc ctgttaggag ataattcatc
     5761 aaaaactcct actgctgtca gtgattgcag taactctaat ttcagccaac gcttatcgat
     5821 ccgtatgagg aattgatcca ctgactggaa cgggccattt tgttttcttt cgtttaatat
     5881 atcttctaca aaatcacgcc gaataccttt tatcgctgtc agtccgaatc tgatttcttc
     5941 cttattgacc aactcaaaac tggaattact ttgattaatg gacggcgagg aaagtttgag
     6001 tttattttta cgtgcttctg caatatattc tttcaatttt gatgtgttat gccgaacaga
     6061 attcatcagg ctggtaaaga aagcacctgg atgatgggct tttagatacg ccatttggaa
     6121 tcccacgaat gaataagcaa atgcatgtga ccgattgaat ccatagtttg caaatttttc
     6181 gatatattca tatacggtcg ctgctgtttt ttccgaatat ccctgttgta atgctcctga
     6241 tacaaaatgc gacttttctt catctaatac gtcttttttc tttttactca ctgcccgtcg
     6301 cagaatatct gactgcccta atgtaaatcc agccatagtc gaggcgatct gcatgatttg
     6361 ttcctgatag acgatcactc catatgtgtt tttcaaaatc gggatcagtg aatcatctgg
     6421 gtagcgaatg gcttcttttc ctttcttcct ggcaatgaag gtatctatat tttgcatagg
     6481 gcctggtcga tacaatgcat tgactgcggc aatatcttcg atgttttctg gatctaatct
     6541 tcgtaaaacg ttccggatac cagcagattc aaattgaaat actcctgagg tttcgcctcg
     6601 ttgaaacaag agcagcgttt ttgcatcatt tagcgggatc tcttttaatc ggatctcata
     6661 cccttctact cgcttaacag ctttcaaagt aaaatcaata atcgataagt tgcgtagtcc
     6721 taaaaagtcc attttcaaaa gaccgattgc ttctacctca ttcatcgtat actgggtcag
     6781 aaaagcttca tcagaaccgc gttggagcgg aactagttca agtagattct tatcgctgat
     6841 aactacacct gctgcgtgag tcgaaacatg tcttggcaat ccttctaaaa tcactgcagt
     6901 tttgaataaa agttggtttt tttcgcttgc ctgaactaat tctactaatt gatgcgaagt
     6961 tttataagct tgggtcaatg tgattttcaa ttgattgggt attgcttttg accagcggtt
     7021 tgcttcactt tgcgataaac caaacactct agctgcatct ctaagaacca tttttgctgc
     7081 cattgtgcca aatgttgcga tttgtgccat atgatattgt ccatactttt ctcgaacata
     7141 attcaatact tcttcacgtc gattgtcagg aatatccaaa tcgatatctg gcatcgtaaa
     7201 gcgttcgggg tttaaaaagc gttcgaacag caaatcatat tctaatggat ccacatctgt
     7261 gatttctaac acataggcta ctaatgaacc cgcagcagaa ccacgacctg caccggtaac
     7321 gattttgttt ctatgagcaa aagccattac atcccatacg atcaagaaat aatcatcgaa
     7381 tcccatttga tggatgacag ataactcgta gtccaaacgt tcttggtatt cctttgtata
     7441 gtcagtgatt cggcgttcca cttgcgaata gcataactct cttaaatatt ctccagcttg
     7501 ttttccatta ggaactggat aatgcggaag taatttctga tggaactgga attcaaatga
     7561 aatcgattca gctaaacgct gggcgcctat tacagcttgg gaaagacccg ctttttcgaa
     7621 tcgtttgatc atttcttgtt ctgaaagaag atagacattt gctgttagtg gtaaagatgc
     7681 agataaattt tctaaaggta tttggcttcc ctctttgata tgtttcatca cttcaagtgc
     7741 aaaaagttct tcttgttgta aactagcgat gggatgtaat gcacaaagcg aataattttc
     7801 ttttatcaca tactgatacc attcaggcaa ttgatcaggc gtgttttctg tcaagccgat
     7861 ataaaaattt ctagtaaaaa cattttcaag taaaaactgc caatgaccga aaaagttatc
     7921 ctctttattg aaagcctcag aaacagaatg atttgccgga acaacaaacg ctagatggtc
     7981 ggtttctgtc atttctgcaa gttccaattt ttcttggatc atttttcggc tggaaagttt
     8041 catcagctgc tgataaccta tttcatcttt tgcgtacgca agcaagccat aatttttttc
     8101 ttcataagta taactaagat gtaatccaat gattggctgt actccttctt ctacacaaat
     8161 acgatagaat tcaggtgcac cgtataagac atctttatcc gttatggcta atgaagtgta
     8221 gccttgtttt tttgcttctt gtacatattc tcgaatacgt atcgtacttt gtaaaagaga
     8281 ataagaagta attgtataaa gttgtgggaa aaacatcttg cattccgcct tttttttcgt
     8341 taaaattcac tagcgttaaa aggtttgatc cttttacttt cattaagata gcaggcgctg
     8401 aagttgatta ttccacttca tttgcttgct tgtaatctgt aggaatgagt tctttcgcaa
     8461 gaactcaaat tttattgaga tttggtctcg tttctttaca ttcaaagaaa atctggtaaa
     8521 attaagatag aaaagaggtg ttctttatgc gatatatcgt tacattattc tgggctgtcg
     8581 ttctaggtca agtagtcggt tatattggtg ctgcattaac aagcggaaca tatgatttta
     8641 ctttgacaac aatcatttca ttcattgcgg gtgtcattat ccttttgatt ggtgcagttg
     8701 cgccaagaaa agaaacctct gcccattcgt aaaaaaacag ccaagagctt gagatttctc
     8761 aagctctttt ttattttcta ctcctcacca ccattataat ctgctgcgaa gaactttacg
     8821 aaagttgaat aaagaaagaa gaatatttga cagaacaaac aaacttgtca caataaaaac
     8881 agcactgtaa ttataagcat gcgcgactgt cgatcctagc atgggaccta aaacttgtcc
     8941 aaagttgcta aacatctgat tgtagctata gattcggctg actccttctt gaggcgtaat
     9001 cttactgatc agtgtattga cagaaggcat caaagcgcca gttgaaaagc ctaaaataaa
     9061 gcgaagtata cctaattgga gcggtgtagt gacgaatgcc ataggtaaat aacagcaaaa
     9121 tgataaaatg agtcctccaa ttagaacttt ttgattccca atcttatccc ctagttttcc
     9181 tagtttcggt gaagaaaaga cagcggaaac accagctatc gaaacaatca agccgctgac
     9241 aaaaaggata ttttctgtac ttccgctcaa ttcacgaata tataaggtca aaatagggct
     9301 gatcgtagtg attcctatct gtaaaatcaa ggtcgtaatg aagagaccga tcaaaataga
     9361 gagatgatcc atttttgaaa aaatttcttt ggtgcttatc agatcttttt tctcgattgg
     9421 atggaaatct tctttgacta agaaaatggt caataccgtt gtgatcatca acaaagcccc
     9481 tgtgatcaag aatacatttt ccataccaaa ccactgagcc agtgcaccgc ccattgaagg
     9541 tccgatcaga tttccagcaa tcgctccggt agacaatgtt cctaacgccc atccgctctt
     9601 ttctctaggt gcctgtgaag caatcatcgc tgtggcattt ggaatatatc cagacaaaat
     9661 cccattccaa aaccgcatga tcaaaagcca atacgcgttt ggtacaaaag ccaaagatcc
     9721 cattgttaat gtcatccctg ctgctgcacg gatcatcatg agttttcggc cttttcgatc
     9781 agctagattt ccccagattg gtgcaaccac ggcagatgca aaagcagtca cagagattgc
     9841 tagtcccgaa aacaattcga tttgatcttt tggtgttcct agttgctcaa cataaactgg
     9901 tatgaatggc ataactaaac taatacttgc accagtgaaa aaacagccaa tccacgcaat
     9961 cactaaattt tttctccaat taatctccat ctatcatccc tctttcgtct cttttatcat
    10021 acctattttc gaataaacaa gcaacgatct cgccagtaaa aagagaaaaa tcccgcaaag
    10081 gtcattttat atgtaacgtt ctttttatgt aaaacaaaaa gagatcagaa caaatactgt
    10141 tccaatccct tctctttagt taaattgttg ctagaatgat gaagttgata atgaataaaa
    10201 tatcaacgat ccacaaagca acagaaactt gattgtattt tcctttgatt actttcacaa
    10261 ttgtatagaa aataaatcct gctgcaatcc cataggaaat gctatagcac aatcccataa
    10321 agatcgatgc aaagaaggcc ggtaaagctt cttccatatc tagccatttg atgtctgcaa
    10381 aagaagccat catcattact ccaactaaaa tcaatgctgg cgcagttgct tgatttggta
    10441 caatggcgat cagtggagag aataaactac ttaatgcgaa tagcactgcc actactactg
    10501 aagtcaaacc agtacgtcca ccggccccga tcccagctgc agattcgaca taagttgttg
    10561 tattcgatgt accaaagata gcccccacag aagtagcgat cgcatcggca aatagtgctt
    10621 tatccatttt tgttttgaac ccacgaccat cttccaacgc gatctcgtct tcttttgaga
    10681 aaatacctgt gcggcgtcct gtaccgataa atgttccgat cgtatcgaaa gtatcagata
    10741 aactgaatgc gatgatcgtc atcaatactt gaggaatctt ggaagaatca ctgaataaag
    10801 attgcatgcc ttcagaacca aatgctgcac cgaaagttgt tcctaattct ttaaatgaat
    10861 tacctaacga attcgtttgc caatcaatgg aacttaaatc aacaacaccc ataaaaatac
    10921 caaggactgt ggtcgctacg ataccgataa gaatagcccc acggacattt tttacaacta
    10981 aaatggctgt cagtaccaaa ccaatcacag ccaataagat aggagcgttg tcaaagttgg
    11041 ctaacgcagg gacgattcca ccatttatcg taacatttgt cgcttttccg ccttcaacga
    11101 cagagctcga aatagctgac tggtctgctg aaaaagataa gaatcctgca tttttgattc
    11161 cgacatacgc aacgaaaata ccgatcccgc caccaatcgc atgttgaaga ctttcgggaa
    11221 tcgcccgaat aatcattttt cgaatatttg tgacagtaat aaaaatattg attaatccgc
    11281 aaataaacac cattgccaag gcttgttgcc aagaataacc aagcccaaaa acgaccgtaa
    11341 aagtgaaaaa tgcgttcaat cccataccag gtgcctgagc atatggtaca tttgcgaaca
    11401 atcccattac cagcgtacca ataatcgatg caatgattgt cgctagaaat actgcttgga
    11461 agggcatacc tgatgctgac aaaatcgtcg gatttacgaa taagatataa ctcatggcaa
    11521 agaatgtcgt tactcccgcc attatttcag ttgatacatt tgtattgttt ttctttaaac
    11581 cgaaaaactt ttccataaaa agttccactc cctgaatttt tttctgatgg aaaactataa
    11641 taataaaaaa taagtaaaat agggcaaatc catcgaacaa tttcaaatta tatagacgtt
    11701 tcattcgctt ttcaacgttt ttttaacaaa aaaagcgaaa ataatactta acgttcgtgt
    11761 ttagcttatg tttagctatt tatatagcca taactgtagt ttttgttagg aatagctgat
    11821 tgctcttgtt aattacctaa aatatgctag actaaaacaa atgctagttg aggaaggaag
    11881 gacccttatt gaataaaaaa ttaattgcca tcgatctgga cggaactacc ctcaatcaag
    11941 attcgatgat tacatctaaa acaaaagaga ctctaaaaaa agcaatcaat gccggtcatc
    12001 atgtcagtat tgctacagga cgcccattcc gaatgagcca tcagttttac caacaattag
    12061 aattaacaac accgatggtt aattttaacg gcgcattagt acacatccct aatcagcact
    12121 gggatggtga aagagaaacg ttgatcaatc gtgaaatcgc ttttgaaatc ttatcgcaaa
    12181 aaaagcagct aaatttagat tttatcgctg ctgaaaatcg tgatactttt tttattgaca
    12241 gttttgattt ctttgatgaa aaaatttttg cttcttctcg tccaggagag aagaatttgc
    12301 tttctcctaa aaatttgacg acaaatccta catctttgct tgtccgaaca gacaaacgtt
    12361 ttgcaggagc tgtatctgct gaattaacac gtcaatttgg cagttatgtc gatgttcgga
    12421 catggggtgg acctactgcc atcttagaga ttgtttcaaa aggaatccaa aaagcaaaag
    12481 gcgtgcaaga gattgctaac tacctgtcta tcgatcaaaa agacgtcatt gcctttggtg
    12541 acgagcataa tgatttggaa ttgttggatt atgcaggttg gggagtagct atggctaacg
    12601 gtactgacca actcaaaggc attgcaaatg atgtcactcc tttgagcaat caggaagacg
    12661 gtttagctgt ttatctggaa aaactactta aactataata gagaattaga ttccaca
//
LOCUS       DAFBVQ010000074        11510 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.077, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000074 DAFBVQ010000000
VERSION     DAFBVQ010000074.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11510)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11510)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11510
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.077"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(79..2154)
                     /locus_tag="LLC22_002386"
     CDS             complement(79..2154)
                     /locus_tag="LLC22_002386"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728817.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit beta"
                     /protein_id="HBK5435634.1"
                     /translation="MAKDLLLEIGLEEMPAHVVTPSMKQLEEKTAKFLDENQLTYDTI
                     ETFSTPRRLAIKVTNIPERQADSEEEVKGPAKKIALDADGNWTKAAEGFVRGQGLTTD
                     AITFRELKGVEYVYVTKYTHGKEAKEVLTGLADVIKSLTFPVTMHWAEYDFEYIRPIH
                     WIVALLDDEVIPFEILDIKTDRASRGHRFLGEDVTFAHAKEYEEKLNEQFVIASPQKR
                     KEMIITQANELAEKDHWIIDLDEDLLEEVNNLVEYPTVFSGDFEEKYLSVPEEVLVTS
                     MKEHQRYFEVRNDQGMLLPHFISARNGDRVKLENVVRGNQKVLTARLEDAEFFYNEDK
                     KASIDQYVEKLKTVTFHEKIGSIYEKMQRVQVIARIIGEQVGLSEEELMDLQRAAEIY
                     KFDLVTNMVGEFPELQGIMGEKYALLKGEKPAVATAIREHYMPISSEGDLPETTVGSV
                     LAIADKLDSIFSFFAVGMIPSGSNDPYALRRQAYGVVRIIESKKWAFPLSVLQETISE
                     VISKDTDRFGIGLSAGQQQVIDFIKGRLRQLLTTKNIRHDVIEAVLNAEQKDLTKVFA
                     AAQLFKQHLADEDFKPSMEALTRVVNLAKKAELEKQSEVDPELFENEAEKELYKAVEV
                     MKTSFADQTINENYDQLVSLRPLIENYFDQTMVMAEEPAVRKNRLTQLSQIAAMALSL
                     ASLDQIITK"
     gene            complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="LLC22_002387"
     CDS             complement(2156..3073)
                     /gene="glyQ"
                     /locus_tag="LLC22_002387"
                     /EC_number="6.1.1.14"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycine--tRNA ligase subunit alpha"
                     /protein_id="HBK5435635.1"
                     /translation="MSKKLTVQDMILTLQKFWSSNGCMLMQAYDTEKGAGTMSPYTFL
                     RAIGPEPWNAAYVEPSRRPADGRYGENPNRLYQHHQFQVVMKPSPENIQELYLESLRF
                     LGIDPLEHDIRFVEDNWENPSMGCAGVGWEVWLDGMEITQFTYFQQVGGLPCKPVTSE
                     ITYGLERLASYIQEVESVYDLEWADGVKYGEIFKQPEYEHSKYSFEVSDQDLLLSNFD
                     RFEKEAKRCIDENLVHPAYDYILKCSHTFNLLDARGAVSVTERAGYLSRIRNMARSVA
                     KIFVAEREKLGFPLLNKNTANPENVKEAE"
     gene            complement(3457..4269)
                     /gene="recO"
                     /locus_tag="LLC22_002388"
     CDS             complement(3457..4269)
                     /gene="recO"
                     /locus_tag="LLC22_002388"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347340.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein RecO"
                     /protein_id="HBK5435636.1"
                     /translation="MSQLAESKGLILSSRNYKEKDKLVKIFTESSGKMMFYIKGIHRQ
                     NQPLAPALLPFTEAVYIGNFLSEGLSFLSSVKDVHAFRNIQEDIFLSGYGTYLLNLVD
                     AAIEDHQYDPHLFQFTQQALQRMDQGDDAEIITNIFEVQILQRFGIAPIWTHCVVCGE
                     TKGKFDYSSKYGGVICEKHWPMDEHRYHAYPRAVYFVRMFSAISYDKISGIHLKEETK
                     QAIRDLIDQLYDEYVGIHLKSKKFIDQMKSWAHVLKMPEKNMPEKEIPEKEE"
     gene            complement(4412..5311)
                     /gene="era"
                     /locus_tag="LLC22_002389"
     CDS             complement(4412..5311)
                     /gene="era"
                     /locus_tag="LLC22_002389"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase Era"
                     /protein_id="HBK5435637.1"
                     /translation="MPEHKSGFVAIVGRPNVGKSTLLNRIVGQKIAIMSDKAQTTRNK
                     IQGVYTTPEAQLIFIDTPGIHKPKHRLGDFMVEAAYTALKEVDAVLFMISADQKRGRG
                     DDFIIERLKNVHSPVYLIINKIDKIHPDELLGIIEDYSTQMPFAQVIPISATEGNNVE
                     RLMDVLVSEMPEGPQYFPDDQVTDHPEYFIVSELIREKVLFLTRDEVPHSVAVVVDSM
                     KRNENDKIHIQATIIVERDSQKGIIIGKGGKMLKQVGTKARKDIENLLGDKVFLELWV
                     KVQKDWRDKKVYLQDFGYRKDEY"
     gene            complement(5326..5721)
                     /locus_tag="LLC22_002390"
     CDS             complement(5326..5721)
                     /locus_tag="LLC22_002390"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631379.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="diacylglycerol kinase family protein"
                     /protein_id="HBK5435638.1"
                     /translation="MDSKDKNVEKNKHFLMSVEFAVQGVKTVFEEERNMRKHVAFGIL
                     ALFMGVIFQIDRIEWLWLLLAVFLVWIVEIINTVFENVVDMFTDFHFHPIGKKIKDMA
                     AGAVLVTACFAVIIGLILFVPKIYHLLFN"
     gene            complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="LLC22_002391"
     CDS             complement(5705..6181)
                     /gene="ybeY"
                     /locus_tag="LLC22_002391"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322767.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="rRNA maturation RNase YbeY"
                     /protein_id="HBK5435639.1"
                     /translation="MDITFMDETNQVSEEKMKEIDDLLQFAASYLKLPEETEMSVTFM
                     DNAAIQVINRDYRGKDAPTDVISFALEEEGEDEIPVIFEDGENPLPRVLGDIMISIER
                     AAEQAEAYGHSYDRELGFLAVHGFLHINGYDHMTPEDEKEMFGLQKEILDAYGLKR"
     gene            complement(6198..8390)
                     /locus_tag="LLC22_002392"
     CDS             complement(6198..8390)
                     /locus_tag="LLC22_002392"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313518.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HDIG domain-containing protein"
                     /protein_id="HBK5435640.1"
                     /translation="MLNKTLQKLQEKLGKAALPFLLFLFFIIICGVTFSSVKQKANDF
                     REGQVAEESIRANKTIENTEETEQKRKLAAEAVTPEYTYQKDLADDQNNRIKQLFELI
                     DKTNDAINKSYDEKIDKAKEDENIPKPTTEERIAALKKNFENVNAENVVFYQKLPNNF
                     YSTIFEMTETEIHTVRDESLKLIDEQMSKQVRESELEAFKQEAEEQIQYLNVTPAQQQ
                     MIRYLVDQGIVVNDVLNEKKTEELKQSAREAVQPVMIFQGEIIVREGNQIDASAMKKL
                     ELLGLTNQTTSIFPLIAMVLAVLLQIGVLIYNSLQFQNTGERTKYVLFYVTAMSVSIV
                     LMKFFQLFQTEQATYIPLFYPAAFAPLVLSFFLNRRAGIMAGIFQAVSALFIFYDSIG
                     TNFLTIILMSYVFSGLMATIVRRKRISEQGLSAAMWVIIFPVMMDVILIVYQGMSFGD
                     ATTWLMLVCGFTGALFSFLLTIGLHPYIELMVNDDSVIVLNELSNPNHPLLKQLLEEA
                     PGTYHHSMMVANLSANAVAEIGGRSLLTRVACYYHDIGKIKHASFFVENLPSGAENPH
                     NFLLPEDSKHIIFGHVTDGAKILEDYNMPQMVIDICKQHHGTTLMRYFYIKAKERNPE
                     VTEEQFRYPGPKPQSREAGIVNIADSCEAAVRAMDHPTSEKIESFVHNLIEERISDGQ
                     LDDSGLTLKEIRKVEKSLISGLSSTFHSRIKYPKMKTEVEKIKEEQEE"
     gene            complement(8414..9385)
                     /locus_tag="LLC22_002393"
     CDS             complement(8414..9385)
                     /locus_tag="LLC22_002393"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631377.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PhoH family protein"
                     /protein_id="HBK5435641.1"
                     /translation="MTEESSSLEIRLTAADDVSMLLGAHDKHIKLIEETTETTIHTRG
                     EIIQIIGEQSQISLAASVIRTLQELIKRGIHVSTPDVVTALKMGQKGTLDYFVEMYEE
                     EIVKDRNGKPIRVKNSGQKKYVESVAKHDIVFGVGPAGTGKTFLAVVLAIAALKKGEV
                     QKIILTRPAVEAGENLGFLPGDLKEKVDPYLRPVYDALYQIFGLDHTNRLMERGVIEI
                     APLAYMRGRTLDDAFVILDEAQNTTVAQMKMFLTRLGYQSKMIVNGDTSQIDLPRGTT
                     SGLVHAERTLKQIKKIDFVNFEASDVVRHPVVAEIIKAYEKADLHQE"
     gene            10090..11469
                     /gene="brnQ"
                     /locus_tag="LLC22_002394"
     CDS             10090..11469
                     /gene="brnQ"
                     /locus_tag="LLC22_002394"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="branched-chain amino acid transport system II
                     carrier protein"
                     /protein_id="HBK5435642.1"
                     /translation="MEETKTYSWKQLLMVSSLIFGMFFGSGNLIFPVHLGQMAGSNWI
                     SAGVGFAISGALFPLLAILAVVVTKSDGLYDLAKPVGKWYAALFLILVHLTIGPFFGT
                     PRTAATAFEMAAKPFLPEKYDSLGMFLFSALFFLLAYFLTVHPTRLVKYVGKYLNSLF
                     LALLAIIFVVSLFQPMGNLNQSAADSYQTNALTNGVLEGYNTVDAVALLALSVTFVHA
                     VRDLGFKDKKVTELTAKAGSLSVALEVMIYFGLVLLGAMSLNKMSLSENGGTALSQIT
                     NFYLGNFGASFLGVMVTLGVFTTAMGLVVSFAQDFHKLFPKVSYMTWLRLTTFVSFVV
                     ANAGLDNIIQWSLPVLMLLYPLSLALILLSLTAKFFQKSPFVYQVTMFFSAVPAVLDM
                     LANSPALVSQQTVVASLLGFYHHYVPFAALGLGWVVPTLLGYAGSLLFYYVYRVSGYK
                     QEASELPEE"
BASE COUNT         3107 a         2419 c         2104 g         3880 t
ORIGIN      
        1 ttatttatat ttataacaaa taaaccagag aaatagccta ttttgtgcct gttctctggt
       61 ttatttacat attagaaatt attttgtgat gatttgatct aaacttgcta gtgacaaagc
      121 catggcagca atttgactta attgcgttaa tcggttctta cgtactgctg gttcttctgc
      181 catgaccatc gtctgatcaa aataattttc gatcagtggg cgaaggctta caagctgatc
      241 ataattttcg ttgatcgttt ggtcagcaaa gcttgttttc attacctcta ctgctttgta
      301 cagttctttc tccgcttcgt tttcgaacag ttcagggtct acttctgatt gtttttcaag
      361 ctccgctttt ttcgctaagt tcacgacacg tgtcaaagct tccatcgatg gtttgaagtc
      421 ttcatctgca agatgctgct tgaacaattg tgctgctgca aatacttttg tcagatcttt
      481 ttgttctgcg ttcaaaacag cttcgatgac atcatgacgg atattcttcg ttgtcaataa
      541 ttggcgcaga cggcctttga taaagtcgat cacctgttgt tgtcccgctg acaagccaat
      601 gccaaaacga tccgtatctt tactgataac ttcactaatc gtttcttgca gaacagacaa
      661 aggaaaggcc cattttttcg attcgatgat tcgaacgaca ccatatgctt gacggcgcaa
      721 agcatatgga tcgtttgagc cacttgggat catcccaact gcaaagaaag aaaagatact
      781 atctaattta tcagcaatcg ctaaaacaga acctactgta gtctcaggta aatctccttc
      841 actggatata ggcatgtaat gttcacggat cgctgttgct acggctggtt tctcgccttt
      901 aagcagagca tatttttctc ccatgatccc ttgtagttca gggaattctc ctaccatgtt
      961 ggttactaga tcaaatttat agatttcagc agcgcgttgc agatccatca attcttcctc
     1021 agacagtcct acttgttcgc ctatgatgcg agcgatgact tgtacccgtt gcattttctc
     1081 atagatgcta ccgatttttt catggaaagt aacagttttt aatttttcaa cgtattggtc
     1141 gattgaagct ttcttgtctt cattataaaa gaattccgca tcttctaaac gagcagtcaa
     1201 tactttttga ttgcctcgta ccacattttc caattttacc cgatcgccat tacgagcaga
     1261 aataaaatga ggaagcaaca taccttgatc gttccgtact tcgaaataac gttgatgttc
     1321 tttcatagaa gtgactagta cttcttcagg aacagataga tatttttctt cgaagtcgcc
     1381 agaaaagaca gttggatatt cgactagatt gttgacttct tctagtaaat cttcatctag
     1441 atcaatgatc cagtgatctt tttctgctaa ttcgtttgct tgtgtgatga tcatttcttt
     1501 tcttttttgc ggtgaagcaa taacaaattg ttcatttaat ttttcttcgt attcttttgc
     1561 atgcgcaaat gtcacatctt cgcctaagaa acgatgacct cttgaagctc tgtctgtttt
     1621 gatatccaag atctcaaacg ggattacttc gtcatctaac aatgccacga tccagtgaat
     1681 aggacggata tattcaaaat cgtattctgc ccaatgcatc gttactggga aagtgaggct
     1741 tttaatgaca tctgctaaac ctgtcaatac ttcttttgct tctttgccgt gagtgtattt
     1801 cgttacatag acatattcca cgccttttaa ttctctaaaa gtgatagcat ctgtcgtcag
     1861 accttgtccg cggacaaatc cttccgctgc tttcgtccag tttccatctg cgtccaaagc
     1921 aatttttttg gctggtcctt tgacttcttc ttcactgtct gcttgacgtt ctggaatgtt
     1981 tgttactttg attgctaaac ggcgcggtgt agaaaatgtt tcaatcgtat cataagtcaa
     2041 ttggttttca tctaaaaatt ttgctgtttt ttcttctaat tgtttcatgc ttggtgtgac
     2101 aacatgagca ggcatttctt ccagcccaat ttcaagtaat aagtcttttg ccatcttatt
     2161 cagcctcctt cacgttttct ggatttgctg tgtttttatt caataaaggg aatcctaatt
     2221 tttcgcgttc tgccacaaag attttggcta cagaacgagc catgttgcgg atacgggaaa
     2281 gataacctgc acgctccgtt acggatactg caccgcgggc atctaataaa ttgaatgtat
     2341 ggctgcattt caaaatataa tcatacgctg gatgaacaag attttcatcg atacagcgtt
     2401 tagcttcttt ttcaaaacga tcaaagttgc ttagtagcaa gtcttggtcg cttacttcaa
     2461 aagaatattt ggaatgttca tattctggtt gtttgaagat ctcgccatat ttcacgccat
     2521 cagcccattc taagtcatag acactttcaa cttcttgaat atatgaagca agacgttcta
     2581 gtccataagt aatctcagaa gtaactggtt tacaaggtag tcctccgact tgctggaagt
     2641 acgtgaattg tgtaatctcc atcccatcaa gccatacttc ccaacccaca ccggcacaac
     2701 ccatcgatgg gttctcccag ttgtcttcaa caaaacgaat atcgtgttct aatggatcaa
     2761 ttcctaaaaa acgcaagctt tctaaataaa gctcttggat attttcaggt gaaggtttca
     2821 ttacgacttg aaattgatga tgctgataca aacggtttgg gttttctcca taacgcccgt
     2881 cagctggtcg gcgggatggc tctacataag cagcattcca tggttccggt ccgattgccc
     2941 gtaagaatgt atatgggctc atcgtacctg ctcctttttc tgtatcataa gcttgcatca
     3001 gcatgcagcc gtttgatgac caaaattttt gtaatgttaa aatcatatct tggacggtca
     3061 attttttact catctgtttt gcccctttca atttttaagc gttgctgtca ataagaatac
     3121 aggaaagaaa acgacaaaaa gtccctatgt ctgattacag acatagggac gaataatttc
     3181 gcggttccac cctacttccg aataaagatt cggcagcttc atttatcgta ctcgcaagtg
     3241 cctcttcaaa aatcgtttgg gtccggcttc cactctcccg aactcgctaa accacgtgtt
     3301 ttttactgat cttggtcaat gtacgtattc attttgcagt tttcttgttt atataataga
     3361 tcctctcagt gaacgatcta tttaatctac ggttaataat agacggaagt ccctgtattt
     3421 gtcaaatagt tttgattttt ttgttgtatc tttcatttat tcttcttttt caggtatctc
     3481 tttttcaggc atatttttct ctggcatctt taatacgtgt gcccaagact tcatttgatc
     3541 aatgaacttt ttgcttttta gatgaatacc gacatattca tcatacaact ggtcaatgag
     3601 gtcacggatt gcctgcttcg tttcttcttt caagtggatt ccactgatct tatcataaga
     3661 aatagccgaa aacattcgaa cgaaataaac agcgcgagga tatgcatgat aacggtgttc
     3721 gtccattggc cagtgtttct cgcatatcac gccgccatat ttggaagaat agtcaaattt
     3781 tccttttgtt tccccgcata cgacacagtg cgtccaaatt ggcgcgattc cgaagcgttg
     3841 cagtatttga acttcaaaga tattcgtgat gatttctgca tcatctcctt ggtccatccg
     3901 ctgcagagct tgttgcgtaa attggaataa gtgcgggtca tattgatgat cttcgattgc
     3961 tgcatctact agatttagca aatacgtacc ataaccgctc aaaaagatat cttcttggat
     4021 gttccgaaac gcatggacgt ctttgacact gcttaaaaac gacaaacctt cacttagaaa
     4081 attaccgata tagactgctt cggtaaaggg gagcaaagcc ggagctaatg gctgattttg
     4141 ccgatggatt cctttgatat aaaacatcat tttgccagaa gattccgtaa agattttgac
     4201 taatttatct ttttctttgt aattacggct agataaaatc aagcctttcg attctgcaag
     4261 ctggctcata ttctccctcc taaaaaataa atctggaaaa gcagattctg ccgatccaga
     4321 ttatttatgt tacgatcttt cgctgttttt ctcaacgtac ggatttttat ccagtttatt
     4381 tctataccta acctataaga agtccagaat atcagtactc gtcttttcgg tagccgaagt
     4441 cttgcagata gacttttttg tctcgccagt ctttttggac tttgacccaa agttctagaa
     4501 atactttgtc tcctaaaaga ttttcgatat cctttcttgc tttcgttcct acttgcttca
     4561 gcatttttcc acctttgccg ataatgattc ctttttggct atctctttca acgatgatcg
     4621 tggcctggat atggatttta tcattctcgt ttcgcttcat cgaatcaaca acgactgcga
     4681 cagaatgagg cacttcgtct cgtgttaaaa acaagacttt ctcacggatc aattcagaaa
     4741 cgatgaagta ttcaggatga tcagtcactt gatcatctgg aaaatattgt gggccctctg
     4801 gcatttcact gactaataca tccattaagc gttcgacatt gtttccttct gtagcagaga
     4861 tcggaatcac ttgtgcaaaa ggcatctgcg tcgaataatc ttcgatgatt cccagcaact
     4921 cgtctggatg gatcttatcg attttattga taatcagata aactggagaa tgcacgtttt
     4981 ttagacgttc aataataaaa tcgtctcccc ggccgcgttt ttgatcagca ctgatcataa
     5041 ataagactgc atccacttct ttcaacgcag tgtaagctgc ttctaccata aaatctccta
     5101 gacgatgctt tggtttatgg attcctggtg tatcgataaa aatcagctga gcttctggtg
     5161 tagtatatac tccttggatt ttatttctag ttgtctgtgc cttgtcactc ataatggcaa
     5221 ttttttgacc cacgattcgg ttcaataatg tggattttcc tacattcggg cggccgacga
     5281 ttgcgacaaa ccctgattta tgttctggca tatacgttct cctttttaat taaacaacaa
     5341 atgatatatt ttagggacaa ataaaatcaa cccaatgatg acagcaaaac aagcggtcac
     5401 taaaactgct ccagctgcca tatctttgat ttttttccca atcggatgaa aatgaaaatc
     5461 cgtaaacatg tccactacat tttcaaaaac agtattgatg atctctacta tccaaacgag
     5521 aaaaacagct aaaagcagcc ataaccactc tatccgatca atctggaaaa tcacgcccat
     5581 aaataaagca aggataccga acgcaacatg tttcctcata ttgcgttctt cctcaaaaac
     5641 ggttttgact ccttggacag caaattccac ggacatcagg aaatgtttgt ttttctctac
     5701 gtttttatct tttgagtcca taggcatcca agatctcttt ctgtaaacca aacatttctt
     5761 tctcatcttc tggtgtcata tggtcatacc cgttgatatg caagaatcca tgtaccgcta
     5821 aaaagccaag ttcccgatca tatgaatggc cgtaagcttc tgcttgttca gcagcacgtt
     5881 caatagagat catgatgtct cctagtacac gaggcaatgg attctctcca tcttcaaaaa
     5941 tcactgggat ttcgtcttcg ccttcttctt ccagagcaaa actgatgacg tctgtcggtg
     6001 catcttttcc acggtaatca cgattgatta cttggattgc cgcattgtcc atgaaagtaa
     6061 cagacatttc tgtttcctct ggcagcttta aataagatgc tgcaaattgc agcaagtcat
     6121 cgatttcttt cattttctct tctgagactt ggtttgtttc atccataaag gtaatatcca
     6181 ttatacatcg cttctttcta ttcttcttgt tcttccttta tcttctcaac ttctgttttc
     6241 attttaggat atttgatccg agaatggaag gtgctactta aaccgctgat caatgatttt
     6301 tccacttttc ggatttcttt caaggtcaat ccactatcgt ctaattgacc atcggaaata
     6361 cgctcttcga taagattatg gacaaaactt tcgatttttt cgctcgttgg atgatccatt
     6421 gcccgtactg cagcctcaca actgtcagca atattgacga tccctgcttc acgactttgc
     6481 ggttttggtc caggataacg gaattgctct tctgttactt ccggattgcg ttctttcgct
     6541 ttgatgtaga aataacgcat tagcgtggtt ccatgatgct gtttgcaaat atcgatcacc
     6601 atttgcggca tattataatc ttccaatatt ttggctccat ctgtcacatg tccaaagata
     6661 atatgtttac tgtcttctgg caataagaaa ttgtgcgggt tttccgctcc tgaaggcaag
     6721 ttctcaacga aaaagctagc gtgtttgatc ttgccgatat catgataata gcaagctact
     6781 cgagttagta aagaacgtcc gccgatttct gctacagcgt tagcacttag attagctacc
     6841 atcatactat gatgatacgt acctggcgct tcttccagca actgtttcaa taaaggatga
     6901 tttggattgc tgagttcatt taatacaatt acactgtcat cattgaccat caattcaata
     6961 tatgggtgta gaccgatcgt cagcaagaat gagaagagtg caccagtgaa cccgcagaca
     7021 agcattaacc aagtcgttgc atcaccaaag ctcattcctt gatagacgat caaaatgaca
     7081 tccatcatca caggaaaaat aatgacccac atggcagcag ataatccttg ttctgagatc
     7141 cgtttacgtc tgacaatcgt tgccatgagc ccagagaaaa cataagacat caagataatc
     7201 gttagaaagt tcgtgccaat cgaatcataa aaaatgaaaa gtgcggatac tgcttggaaa
     7261 ataccagcca tgatccctgc tcttcgattc aagaaaaagc ttaaaacaag tggtgcaaaa
     7321 gcagcgggat aaaacagcgg gatataagta gcttgttccg tttggaataa ttggaaaaat
     7381 ttcatcagca ctatgctgac tgacatagct gtcacataga aaagaacgta ttttgttctt
     7441 tctcctgtat tttggaattg aagtgaatta taaatcagta cgccgatttg aagcaaaaca
     7501 gctaaaacca tggcaattag cggaaaaatc gaagttgttt gattagtcag tcctagtaat
     7561 tccaattttt tcatagctga agcatcaatt tgattacctt cacgaacaat gatttctcct
     7621 tggaagatca tcactggttg tacagcttct cgtgcggatt gtttcaattc ttctgtcttt
     7681 ttctcattca atacgtcatt cactacgata ccttgatcca ctaagtagcg aatcatttgt
     7741 tgttgtgctg gtgtgacatt caaatattgg atttgctctt ctgcttcttg tttaaaagct
     7801 tccaattcac tttcacgaac ttgtttgctc atctgttcgt caatgagctt cagactctca
     7861 tccctcacag tatgaatctc agtttcagtc atttcaaata tcgtcgaata aaaattgttc
     7921 ggtagttttt gataaaacac aacattttct gcattcacat tttcaaaatt tttcttcagc
     7981 gcggcgatcc gctcttctgt agtaggcttt gggatatttt catcttcctt tgccttatca
     8041 atcttttcgt cataagattt gttgatggca tcattcgtct tatcgatcaa ttcaaatagt
     8101 tgcttgatcc gattgttctg gtcatctgca agatcttttt ggtaagtgta ttctggagtg
     8161 actgcttctg ctgccagttt tcttttttgt tcggtttctt ccgtgttctc gatcgttttg
     8221 ttcgcacgga tactttcttc tgctacttgg ccttctctga aatcattggc cttttgtttg
     8281 acactactaa atgtaacgcc gcagataatg ataaaaaaca agaacagcag gaaaggcaat
     8341 gctgcctttc caagtttttc ttgtagtttc tgcagtgttt tattcaacat gtgcttatcc
     8401 tcctaagcaa agcttattct tgatggagat ctgccttttc ataagctttg atgatttcgg
     8461 caactacagg gtgccgaaca acgtcacttg cttcaaaatt aacaaaatcg attttcttga
     8521 tttgctttaa tgttcgttct gcatgaacaa gaccacttgt tgtccctcga ggcagatcaa
     8581 tctgactcgt atctccattg acaatcattt ttgattgata accaagacgt gtcaggaaca
     8641 ttttcatctg agcaactgtc gtgttctgtg cttcatccaa aataacgaat gcatcatcca
     8701 atgtccgccc ccgcatgtaa gctaaaggag caatttcgat cacgcctcgt tccatcaatc
     8761 ggttcgtatg atctaatcca aaaatttggt ataaagcatc ataaacagga cgcagataag
     8821 gatctacttt ttcttttaga tccccgggaa gaaagcctag attttcccct gcttccacag
     8881 caggccgcgt caaaatgatt ttttgcactt cacctttttt caaggcagcg attgctaata
     8941 ctactgcaag aaaagttttt cctgtcccgg ctggtcctac gccaaatacg atatcatgtt
     9001 tggctaccga ttcgacatat ttcttttggc cgctgttttt tacccgtata ggttttccat
     9061 tacggtcttt gacgatctct tcctcataca tctcaacaaa ataatctaat gtgccttttt
     9121 gccccatttt cagtgccgtc acgacatctg gtgtacttac atggattcct cgtttgatca
     9181 attcctgcaa tgtccgaatg actgaggcag ccaaggaaat ctgggattgt tcgccaatga
     9241 tctgaatgat ttctccacgt gtatggatgg ttgtttctgt tgtttcttca atcagtttta
     9301 tgtgcttgtc gtgtgcacct aaaagcatgc tgacatcatc agcagccgtc aatctaatct
     9361 ctaaagaact agactcttcc gtcaaaaata gacatcccct ttttttcgat tcattctttc
     9421 ctattttacc atactcagaa gaaactatat agcaaataag aaaaggttct aaaagagttg
     9481 cttaaccata agtaccaaga aacgttaaaa aatagctgct tccattctct aaaggtctcg
     9541 tttgaataaa aaaagctgat catgtaagct atgcataaga tagaggacaa gtattccgtc
     9601 taacttagca agtattctct gggtattttt cttgtttcaa aaaaagaaaa caaaatattt
     9661 gaaatattct tgcatttcaa aaaaaacagg tgtattataa cgtcaacaaa taaatataca
     9721 gcaaagcgtc gaggaaaaca gtaggctatt cagtgattta ttcccagtga gtcatgtaag
     9781 tgagaaatga caataaatcg aatagacgaa catcatttcc gagtcaatgt cgaaaacgta
     9841 gatcattgtg gctgcctcca ttatcaggcc agcggataac tttatcgaaa agcgtccgtg
     9901 aatgaagaag cttttttaag cgaaaaaagg tggtaccgtt ctagaatcta gagccctttt
     9961 cccaagtgga aaagggcttt ttttatattt taaggtggtg gttttcatgg aatctgatat
    10021 tagtggtatt tctagtttct gcaacgttta ttttgttact caaaatgata attattggag
    10081 gaaaaattta tggaagaaac aaaaacttat tcatggaagc aattattgat ggtcagttca
    10141 cttatcttcg ggatgttctt cgggtcaggt aatctgatct ttcctgtcca cttaggtcaa
    10201 atggctggat caaactggat cagcgctggt gtaggatttg ccatctcagg cgctcttttc
    10261 ccattattag ctatcttagc tgtagtagtg acaaaaagtg atggtctgta tgacttagct
    10321 aaacctgtcg gaaaatggta tgctgccttg ttcttgatcc ttgttcattt aacgatcgga
    10381 ccattctttg gtacaccgcg gacagcagca actgcttttg aaatggctgc taaacccttt
    10441 ttgcctgaaa aatatgattc attaggtatg tttttattct ctgctctttt ctttttactt
    10501 gcttatttcc ttactgtaca tccaacacgt ttggtcaaat atgtcggaaa gtatttaaac
    10561 tccttgtttc ttgcattatt agctatcatt tttgtcgttt ctttattcca acccatgggg
    10621 aatctaaacc aatctgctgc agattcttat cagacgaacg ctttgacaaa tggcgtttta
    10681 gaaggataca acacggttga tgcagtagct ttacttgctt taagtgtcac ttttgtccat
    10741 gcagttcgtg atcttggttt taaagataaa aaagtcacag aattaacagc aaaagctggt
    10801 agcctgagcg ttgcgttaga agtcatgatt tattttggtc tggtccttct cggtgcgatg
    10861 agtttgaata agatgtcttt atcagaaaat ggcggaactg cactttctca gatcactaat
    10921 ttttatttag gtaacttcgg tgctagcttc ttaggggtaa tggtcacatt aggtgtcttc
    10981 actaccgcta tgggactcgt tgtttctttt gcacaagatt tccataaact gttccctaaa
    11041 gtcagttata tgacatggct gcggttaacg acttttgtct cttttgtcgt tgcgaatgcc
    11101 ggattggata atatcatcca atggtcttta ccagtattga tgcttttgta tccattgtca
    11161 cttgcgttaa tcttgctttc cttaacagca aaattcttcc aaaagagtcc atttgtctat
    11221 caagtaacga tgttcttttc tgccgttcca gccgtattgg atatgttggc aaattcgcct
    11281 gcattagtga gtcagcaaac tgtcgtagca agcttactag gattttatca tcattatgtt
    11341 ccttttgctg cattaggact tggctgggtc gtcccaacgt tgcttggtta cgctggcagc
    11401 ttgctctttt attatgtata tcgcgtatca ggatataaac aagaagcaag tgagttacca
    11461 gaagaataac caaatcaaac acaatttaac ataagagata ttaaacagga
//
LOCUS       DAFBVQ010000075        11454 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.078, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000075 DAFBVQ010000000
VERSION     DAFBVQ010000075.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11454)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11454)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11454
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.078"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            51..698
                     /locus_tag="LLC22_002395"
     CDS             51..698
                     /locus_tag="LLC22_002395"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341283.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435643.1"
                     /translation="MEAKITLEPFERILSGYRKVEELAVNVTDCSKLAQKYARFGVEG
                     YRLGNYVGTGYLNRYLECMVDRAPMLIYRQNYLIPLLFRRSDSAFRLFEEEYRMEAFF
                     LLLEWSLKHRPEKILIERNEKIDTKKNKVIDSAYLAFRVSEILDCGGYPISNFQSIDQ
                     FIEWNRIYRLIDNGGIGRHSKVFDPEYPENMEELKMIISLVKLKYPETDLDLYIE"
     gene            complement(791..3070)
                     /locus_tag="LLC22_002396"
     CDS             complement(791..3070)
                     /locus_tag="LLC22_002396"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373478.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5435644.1"
                     /translation="MNEKQLEQTHVDETIELIQIEQNMLDTKQQELTQEMNHSTKDTA
                     NHKIRAGSNEAFYESAVEYRQHEQELLLKYHTLEAQQKRLQTLSVMKDSPYFARIDFK
                     EDRETETLYLGIASLRDLAEETIVIDWRAPIANLYYEGEIGPAFYETETDRIDVDLQL
                     KRQFKIQEGRILSMVDTSEVINDDFLLEILDESSSNHMKNIVSTIQKAQNAIIRDTTS
                     KVMLIEGIAGSGKTSALLQRIAFLLYHNRKWLEAENVLLFSPNHLFSDYISTVLPSLG
                     ESGVPTQTFKNYLVQLLPEFSLLDEQQQESGFLLGEKDPIQVMKSGLTLVDQIDRYIQ
                     GITNYGPLFRDMKINGRTILSKESIRQWYKETNEQLPLHHRLSLLQTKLLKKLGGLQK
                     DETRQQWVKDLAEEQLQELYATDPNLEYTEQKERSLRKKLANQIVRKRFRRIHRGIMN
                     YQFVNITKQYLHFLQTVPLSLLTRHKISETRWQEHLTTVRTHLRQRELRQEDAVLFFL
                     LMRRTYPVTVTHKARYIFIDEMQDFAPSQVALLQALFPKANLTFCGDLNQNVFGNETI
                     VGSLEDLFVDREVTRFQLTTSYRSTKEITDFANHFIVKEHQVETTARKGDLPLLIQGT
                     TDDIKLNWLADTIRTTQGKARYWRTAIIAKTQEECEALYAQLPDELKQQVQLILNESD
                     FMKRSIILLPAFLAKGLEFDRVFLWDVDAEHFSSQQDKLILYTMCTRAMHELTLFTSN
                     NESPLLNNMDISSYEKKVL"
     gene            3348..5171
                     /gene="cadA"
                     /locus_tag="LLC22_002397"
     CDS             3348..5171
                     /gene="cadA"
                     /locus_tag="LLC22_002397"
                     /EC_number="7.2.2.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cadmium-translocating P-type ATPase"
                     /protein_id="HBK5435645.1"
                     /translation="MTHFKKFLLTLLIGGIALLSEFVFHQPALAFAIVAFTGGILAFL
                     MFLEMIKTLRSGRYGVDVLAITAILATLAVKEYWASLMILIMLTGGDSLEDYANKRAG
                     KELQSLLDNTPRIAHRFKEGKLQDIVIDEINIDDQLLVKPGELVPADGRVTKGESSVD
                     ESSLTGESRPETKKPGDQIMSGSLNGDGSIQMIAEKRAADSQYQMIIKLVEESKEKPA
                     RFVRLADRYAVPFTLIAYLIGGISWWFSKDPLRFAEVLVVASPCPLILAAPIALVAGM
                     SRSSKNGIVVKTGTTIEKLARTKTIAFDKTGTLTKGILEVEAIQPVNGIKKEELLLYA
                     ASAEQESSHILARSLVNNVKNSQLYPVSQLKEVTGQGIQAVVNNHEVKIGRASFVSAE
                     EIETSNTAIYVTIDRSFAGTILFSDQIRPEAAKTIKELRKLDVKNLMMITGDGSAIAQ
                     TIAEKVQLDSVHARSLPQDKLTILESIPKDQRPVAMVGDGVNDAPALAAADIGIAMGA
                     HGSTAASESADAVILKDDLLRVAKAVVISRDTMRIAKQSVLIGIFICIFLMLIASTGL
                     IPALFGAVLQEVVDTVSILSALRAKKDPAIFPDSVPKTNIV"
     gene            5218..5397
                     /locus_tag="LLC22_002398"
     CDS             5218..5397
                     /locus_tag="LLC22_002398"
                     /EC_number="5.3.2.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4-oxalocrotonate tautomerase"
                     /protein_id="HBK5435646.1"
                     /translation="MPFVHVELVEGRSPEQLENMMKDITEAVHKNTQAPKEHIHVIIN
                     EMKKGTYGVNGEWKK"
     gene            5734..7674
                     /gene="thrS"
                     /locus_tag="LLC22_002399"
     CDS             5734..7674
                     /gene="thrS"
                     /locus_tag="LLC22_002399"
                     /EC_number="6.1.1.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295368.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="threonine--tRNA ligase"
                     /protein_id="HBK5435647.1"
                     /translation="MIKITFPDGAVKEFESGTTTLAIAESISKSLAKKALAGKVNGKL
                     VDLTRPIEEDASIEIITPDHEDALGLVRHSAAHLMAQAMRRLYPNIHFGVGPAIDSGF
                     YYDTDNGQNQVTAEDLPAIEAEMMKIVKENLPIERRVLSKQEALEIFASDPYKVELIS
                     ELPEEEVITAYQQGEFIDLCRGPHVPSTGRIQVFKLLSVAGAYWRGNSNNQMMQRVYG
                     TAFFDKKALKEYIRLREEAKERDHRKLGKELDLFMVSPEVGSGLPFWLPKGATIRRTI
                     ERYIVDKEVSLGYQHVYTPIMGDVELYKTSGHWDHYQEDMFPPMDMGDGEMLVLRPMN
                     CPHHMMVYKNTIHSYRELPIRIAELGMMHRYEKSGALSGLQRVREMTLNDGHTFVRPD
                     QIKDEFKRTLELMVAVYADFNITDYRFRLSYRDPNNTDKYFDDDAMWEKAQAMLKAAM
                     DELELDYFEAEGEAAFYGPKLDVQVKTALGTEETLSTIQLDFLLPERFDLTYVGEDGE
                     NTHRPVVIHRGIVSTMERFVAYLTEVYKGAFPTWLAPIQATIIPVSVDAHGDYAYEIK
                     ERLQMKGLRVEVDDRNEKMGYKIRASQTQKIPYQLVVGDKELEDATVNVRRYGSKETA
                     VEDLNIFIDAMEAEVKNYSREN"
     gene            7898..8746
                     /locus_tag="LLC22_002400"
     CDS             7898..8746
                     /locus_tag="LLC22_002400"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329060.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5435648.1"
                     /translation="MSVISRIESMMEDYSSAEKKLANYIIGNIEKVPTMTANELAEAS
                     GLSAPTVVRFSKKIGFQSLTDFKITISTELQTGIDEGFSDIEANESFYSIKNKLGNNA
                     QVAIKETVDILEEETIQKVVECLESAETVFLYGVGASSLVVEDILQKWSRVGKPIIFE
                     KDIHVLLPQLVSNEKKKVLWLVSNSGRSADVVALAELAKSMNIEIIALTQFGNNPLSK
                     IADVLVQTSRPKEITNRSAATNSLLAQFATIDIIFYFYMAKNEKLSEKVKKTREAIQE
                     YFMDSK"
     gene            9141..11294
                     /locus_tag="LLC22_002401"
     CDS             9141..11294
                     /locus_tag="LLC22_002401"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002320418.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="penicillin-binding protein 2"
                     /protein_id="HBK5435649.1"
                     /translation="MMKDFMKKILNTSWLEKIRKGAQEPKNKTFRRSHVPFRLNFLFF
                     IIFTLFVALIARLGYLQIVNGEEMEARVKSTSTITVQESTPRGMIYDSTGKALVTNKA
                     NQAITYTRGTQVTAKDLLEIATKLNSLIDVPVDENLTDRDKKDFWLADPKHLKEATKR
                     LSAKEKQLGNSEQYSAMVNKVTADEINLNEEQLKIATIFKRMNSAYELNTVYIKNSGV
                     TDQELAVVAERASELPGVSTGTDWTREYNAASSLKSILGSVTTEKQGLPADEAEKYLA
                     KGYSRNDRVGQSYLEKQYEDVLQGTKTQYEVSLDNEGNVSNQKEIFSGEKGSNLMLSM
                     NAEFQSKVEEILKRNYQTLINNGKAQYSPGAYAVAMNPQTGEVLAMTGFSHEQGSKEI
                     TENALGTITSAFDPGSVVKAGTLTAGWASNAISGNQVLIDEPIRLQGASEKSSVFNRS
                     GQVALDAVKASELSSNTYMIKVALKMLGLDYTPGMGLPSLDEEAKAYQQLRDSFKEFG
                     LGTTTGIDLPNESPGISRSVDYMKKFNADNGKEWYAPGNFTDLAFGQFDTYTPIQLAQ
                     YASTVANGGKRVQPHLVKAIYGNDENGNLGEVKKEIGTTVENTVNISAENMAILREGF
                     HQVVHGTDPYTTAKPLASAKMDLSAKTGTAETVAEGHPDIATVNSNIVAYGPTDNPEI
                     AISVVLPNLLDEQDHINLTIAKEIMDAYYDMFMAK"
BASE COUNT         3701 a         2015 c         2446 g         3292 t
ORIGIN      
        1 agtatcatgt gaaatgatat gaagtatgtg gaagatggac ggggaagaat atggaagcaa
       61 aaatcacttt agaacctttt gaacgtatct taagcggtta ccgcaaagta gaagagttag
      121 ctgtgaacgt aactgattgt tcaaaattag cgcaaaaata cgcaagattc ggcgttgaag
      181 gctatcgatt aggaaactat gtcggtacag ggtatctgaa ccgttattta gagtgtatgg
      241 tggaccgcgc accaatgctg atttatagac aaaattatct gattccgctg ctttttcgtc
      301 gttctgattc agcctttcgg ttatttgaag aagagtatcg gatggaggct ttctttctac
      361 tattagagtg gagcttgaaa catcgtcctg aaaaaattct tatcgaaaga aatgagaaga
      421 tagacacgaa aaaaaataaa gtgatcgata gtgcatacct agcatttcgt gtatcagaga
      481 ttttggattg tggcggctat ccaatcagca atttccaatc aattgaccaa ttcattgaat
      541 ggaatcgaat ttaccgattg atcgacaatg gcgggattgg ccgtcatagc aaggtatttg
      601 acccagaata tccagaaaac atggaagaac tgaaaatgat tatttcgctt gtcaaattaa
      661 aatatcctga aacagatttg gatttatata tagaataaat gaccttaaat gattgaatta
      721 ctttttctgc aattattatt gtaaataaaa agacaactgc taacattaat gatagcagtt
      781 gtctttttac ttacagtact tttttctcat aagatgaaat atccatattg tttaacaaag
      841 gactttcatt attggaggta aaaagggtca attcatgcat cgcacgtgta cacatggtgt
      901 aaaggatcaa tttgtcttgc tgagaagaaa aatgttctgc atctacatcc cacaagaaaa
      961 ctcggtcaaa ctccagacct tttgctaaaa aggctggaag taaaataatg gaacgcttca
     1021 taaagtcact ctcatttaaa atcagctgga cttgttgttt caactcgtct ggcagttgag
     1081 cataaagagc ttcgcattct tcttgtgttt tagctatgat tgctgtacgc caataccggg
     1141 cttttccctg agtcgttcga atggtatctg ctaaccaatt caatttgata tcatctgttg
     1201 ttccttggat gagcaaagga aggtctcctt ttcttgctgt tgtttctact tgatgttctt
     1261 tcacaataaa atgattagca aaatcagtga tttcttttgt ggagcgatag cttgtcgtta
     1321 attggaaacg agtgacttca cggtccacga aaaggtcttc caatgatcca acgatcgttt
     1381 catttccaaa gacattttga tttagatctc cacagaaagt caaatttgct tttgggaaca
     1441 aggcttgcag caatgccact tgtgatggtg cgaaatcctg catttcatca ataaagatat
     1501 agcgagcttt gtgtgtaacc gtcactggat atgttcggcg catcagtaaa aagaatagta
     1561 cagcatcctc ttgacgcaat tctctttgac gcaagtgtgt acgaacagtt gtcaaatgtt
     1621 cctgccacct ggtctcgctg attttatgtc gtgttagaag agaaagtggc acagtttgta
     1681 gaaagtggag atattgtttc gttatattga caaattgata attcatgatc cctcgatgga
     1741 ttcgacggaa tcttttacgt acgatttggt tggccagttt tttacgtaat gaacgctcct
     1801 tttgttctgt atattcaaga tttggatctg ttgcgtatag ttcttggagc tgttcttccg
     1861 ccagatcttt gacccattgc tgacgtgttt cgtctttttg cagaccgcct aattttttca
     1921 ggagcttcgt ttgtaataga gaaagtctat gatgtaaagg taattgttca tttgtttctt
     1981 tataccattg gcgaatcgat tcctttgata ggatcgtacg gccatttatt ttcatatcac
     2041 ggaacaaggg accgtagttt gtgatgcctt ggatatagcg atcaatctga tcgactaagg
     2101 tcaatccgct tttcatcact tgtatcggat ctttttcccc tagcaaaaaa ccactttctt
     2161 gttgctgttc atctagtaaa gaaaactctg gcagcagctg caccaaataa tttttgaatg
     2221 tctgtgtagg cacgccgctt tcacctaatg aaggcaatac agtcgagatg taatcagaaa
     2281 acaaatggtt gggtgaaaat agaagaacgt tttcagcctc gagccacttg cgattatgat
     2341 acaacagaaa agcaatacgt tgaagcaaag cggatgtctt tccacttccg gcgattcctt
     2401 caatcagcat tactttactt gttgtgtccc gaatgattgc attttgtgct ttttgtatcg
     2461 tagagacgat gtttttcata tggttgcttg atgattcatc caatatctct agcaaaaagt
     2521 catcattgat tacttccgac gtatctacca tagataaaat acgtccttct tggattttaa
     2581 attgtcgttt caactgcaga tcgacatcta ttctatctgt ttcagtttca taaaatgcgg
     2641 gaccaatctc accttcataa taaagattgg caattggtgc gcgccagtca ataacgattg
     2701 tttcttctgc cagatctctt aaagaagcga tacctagata taatgtttct gtttcacggt
     2761 cttctttaaa gtcgatacgg gcaaaataag gactatcttt catgacagac aacgtttgca
     2821 ggcgtttttg ctgtgcttca agagtatggt atttcaaaag caattcctgc tcatgttggc
     2881 gatattcaac agcagattca taaaaagctt cattggaacc agctcgaatc ttgtgattag
     2941 ctgtgtcttt tgtcgaatga ttcatttcct gagtcaattc ttgttgtttt gtatccagca
     3001 tattttgttc gatctggatt agttcgatcg tttcatccac gtgcgtttgt tctagttgtt
     3061 tctcattcat cgcatgtttg ctccttccgc cgtaaataac gaattaaaag tatagcatag
     3121 tttttcgaaa aaaggtactt tttaactgat gaatcgaaaa agtaatcctt gctgaatatt
     3181 tttgtttgta gaactgatga attttggaaa cgctgatagt gatagttgtt ttcaattaag
     3241 gcctattgtt ttaaaaagtg ctagtcaagg actatgctta agatgaaaga ggcagctgga
     3301 aatttattac taacctctct aagtcacata aaagaggaga aaaaacaatg acacatttca
     3361 aaaaattttt acttactttg cttattggtg ggatagcttt attaagtgaa tttgtttttc
     3421 accagccggc ccttgcattt gcgattgtcg catttactgg agggattctc gccttcttga
     3481 tgtttttgga aatgatcaag acgttacgtt caggaagata tggcgtagat gtattagcga
     3541 ttaccgcaat ccttgcaaca ttagccgtca aagaatactg ggctagtttg atgatattga
     3601 tcatgcttac gggcggagat agtctagagg attacgcgaa taaacgagcg ggtaaagaac
     3661 tgcagtcttt gttagataac accccaagaa ttgcccatcg attcaaagaa ggaaaattgc
     3721 aggatatagt aatcgatgaa ataaatattg atgaccagtt actagtcaag cctggcgaac
     3781 ttgtacccgc agatggtcga gtgaccaaag gagaatcttc ggtcgatgaa tcttctttga
     3841 caggtgagtc ccgcccggaa accaagaaac ctggagatca gattatgtca gggtctttaa
     3901 atggagacgg atcgatccaa atgatcgctg aaaaacgtgc cgcagacagc cagtatcaaa
     3961 tgattattaa actagtcgaa gaatcaaaag aaaagcctgc ccgatttgtc cgtttagctg
     4021 atcgttatgc agtccctttc acgttgattg cttatttgat cggtggtatt tcttggtggt
     4081 tctcaaaaga ccctttacga tttgctgagg tactggtagt ggcatcacct tgtccactga
     4141 ttctagctgc gcccattgct ttagttgcag gaatgagccg ttcaagtaaa aacgggatcg
     4201 ttgtaaaaac tggaacaacg attgaaaagc tcgcacgtac aaaaacgatt gcttttgata
     4261 aaacaggaac gcttaccaaa gggatattgg aagtagaggc gattcagcca gtcaatggaa
     4321 taaaaaaaga agagctactt ctgtatgcag ctagtgcaga acaggaatct agccatatct
     4381 tagctcgttc gttagtgaac aacgtgaaaa acagccaact gtatcctgtt agtcaactga
     4441 aagaagtgac cggtcaagga atccaagcag tagtcaataa tcatgaagta aagattggac
     4501 gtgcctcttt tgtttcagct gaagaaatag aaacgtccaa tacagcaatc tatgtaacaa
     4561 ttgatcgatc ttttgcagga acgatcctat tttcggatca gattcgccca gaagcagcaa
     4621 agacaatcaa ggagctaaga aaacttgatg tgaaaaattt gatgatgatc accggggatg
     4681 gatctgccat tgctcaaacg attgcagaaa aagtccaatt agattctgta catgcccgta
     4741 gcttgcctca agataaactg accattttag aaagtatccc taaagatcaa agacctgttg
     4801 cgatggtagg agacggcgtg aatgacgcac cagcacttgc tgctgcagat atcggtattg
     4861 caatgggggc tcatggttct acagctgcta gtgaaagtgc agatgcggtc atcttgaaag
     4921 atgatctctt gcgtgtagca aaagcagtag tgatttcaag agatacgatg agaatagcga
     4981 aacagtctgt actgattggc atctttattt gtattttttt gatgttaatt gcaagtacgg
     5041 gactaatccc cgcattattc ggagctgttt tgcaagaagt cgtggatacg gtctctattt
     5101 tgagtgcctt gagagcaaaa aaagatccag ccatttttcc tgattcagta cccaagacaa
     5161 acatagtatg atagaatcga gttgaaaaaa gaacgatcag aaagaggaga gagcattatg
     5221 ccattcgtac atgtcgaatt agtagaaggt cgcagtccgg aacaattaga aaatatgatg
     5281 aaagatatca cggaagctgt tcataaaaac acgcaggcac caaaagaaca catccatgtc
     5341 atcatcaatg agatgaaaaa aggaacatac ggtgtaaatg gggaatggaa aaaataagtt
     5401 tagtttccca cttgattttt ctatttatta gtggttaaat aaacacataa ttgattgatg
     5461 agaaagccaa ctgaatttga gagtcttcga taagagagga aaagctaggc tgaaactttt
     5521 ccaggagaaa accaaaggat gaccactttc gaaacccttg ttgaagcaag ggcggtcgga
     5581 ccgttacaac gcttgaggaa cgcatttgcg tttgaacatt aggtggaacc acgaactttt
     5641 cgtcctagta tctcttttca agagatgcta ggattttttt gtttttcagc ttgatgatct
     5701 gatcaatcaa aacatttcaa ggaggaaact attatgataa aaattacttt tccagatggt
     5761 gcagtcaaag aatttgagtc tggaacaaca acattggcaa ttgctgaaag catttcaaaa
     5821 agcttagcaa aaaaagcttt agctggtaaa gtgaacggaa aactcgttga tttgactcgt
     5881 ccaatcgagg aagatgcaag tattgagatc atcacaccag accatgaaga tgcacttggc
     5941 ttagtccgtc attcagcagc tcatttgatg gcccaagcca tgcgtcgcct ctatccaaat
     6001 atccactttg gcgttggacc agctatcgat tcagggtttt actacgatac agataatgga
     6061 caaaaccaag taactgcaga agatttgccg gcaatcgaag cagaaatgat gaaaatcgtc
     6121 aaagaaaatc tgccgatcga acgccgtgtt ctttcaaaac aggaagcatt agaaattttt
     6181 gcaagtgatc cgtacaaagt agaactgatt agtgaattgc cagaagaaga agtgattact
     6241 gcttatcaac aaggcgaatt catcgatttg tgtcgtggac cacatgttcc atccactggc
     6301 cgtatacaag tatttaaatt attatcagtg gcaggtgctt attggcgtgg aaactcaaac
     6361 aatcaaatga tgcaacgtgt atacgggaca gccttttttg acaagaaagc tttgaaagaa
     6421 tatatccgtc tccgtgaaga agcaaaagaa agagaccatc gtaaactagg aaaagaactt
     6481 gacttgttca tggtttcccc agaagtaggt tctggtttgc cattctggct tccaaaaggg
     6541 gcaacaatcc gacgcacgat cgaacgttat atcgtagaca aagaagttag tctaggttac
     6601 caacatgtat atacaccaat aatgggagat gttgagttgt acaaaacatc tggacactgg
     6661 gatcattatc aagaagacat gttcccgcca atggatatgg gagatggcga aatgcttgtt
     6721 cttcgcccaa tgaactgccc tcatcacatg atggtctaca aaaacacgat ccattcttat
     6781 cgtgaattac caattcgtat cgctgaatta ggaatgatgc atcgctatga aaaatcaggt
     6841 gctttgtcag gtttacaacg tgtacgagaa atgacgttga atgatggtca tacatttgtt
     6901 cgtcctgatc aaatcaaaga tgaatttaaa cgtacgcttg aattgatggt ggcagtatat
     6961 gctgacttca atattacaga ttatcgtttc cgcttgagct atcgcgatcc aaacaataca
     7021 gataaatatt ttgatgatga cgcaatgtgg gaaaaagccc aagcaatgct gaaagccgct
     7081 atggatgaat tagaactaga ttactttgaa gcagaaggcg aggcagcctt ttacggacca
     7141 aaactagatg ttcaagtcaa aacagctctt ggtacagaag aaacattatc aactatacaa
     7201 ttagacttct tattgccaga gcgctttgat ttgacatatg ttggagaaga cggggaaaat
     7261 acgcatcgtc cagtagttat ccaccgcgga attgtttcta caatggaacg ttttgtcgct
     7321 tatttaacag aagtatacaa aggcgctttt ccaacatggt tggcacctat acaagcaaca
     7381 atcatccctg tttctgttga tgcacatggc gattatgctt atgaaatcaa agaacgtttg
     7441 caaatgaagg ggttgcgtgt agaagttgat gatcgtaatg aaaaaatggg ctataagata
     7501 cgtgcctctc aaacacaaaa gatcccttac caattagttg ttggagacaa ggaattggaa
     7561 gatgcaacag tgaacgtacg tcgttatgga agtaaagaaa cagctgtaga agatttgaat
     7621 atctttattg atgctatgga agcagaagtc aaaaattaca gcagagaaaa ctaataggta
     7681 aatttcctgt aaaaaagtag tagatagaaa gcaatccgaa caatagataa caggtattcc
     7741 tcaaagacac agatgctcaa tagaatctgt gggattgatg ggataagata ttctgttggg
     7801 cggattgttt ttttgttttt tatccagtat acgaccgtga ataagggtct gatatggtat
     7861 acttacatag actatcatta aaagggtgga ggaacttatg agcgtaatta gtcgtattga
     7921 aagtatgatg gaagattatt cttcagcaga aaaaaagttg gccaactaca ttatcggtaa
     7981 tattgagaag gtccctacaa tgacagctaa tgaattagca gaagcttccg ggttgagtgc
     8041 gccgacagtt gtacgttttt ccaaaaaaat cggttttcaa agtctgacgg acttcaaaat
     8101 cacgatttca acagaactac agactggaat cgatgaaggt tttagtgata tagaagcaaa
     8161 tgagtccttt tactctatca aaaacaaact tggtaacaat gcacaagtag cgataaaaga
     8221 aacagtagat attctagaag aagaaacgat ccaaaaagtc gtagagtgtt tggaatcggc
     8281 agagactgtt tttttatatg gggttggcgc ctcttcttta gtagtagaag atattctgca
     8341 aaaatggtct cgtgtcggta agccaatcat ttttgaaaaa gatatccacg tcttgctccc
     8401 gcaacttgtc agcaatgaga aaaagaaagt gctttggctt gtttcaaact caggtagaag
     8461 tgcagatgta gtcgcattag ccgagctggc gaaaagcatg aatatcgaaa tcattgcgtt
     8521 gacgcaattt ggaaataacc cgcttagcaa gatagccgat gtactcgtac aaacatctag
     8581 accaaaagaa atcacgaatc gaagtgcggc aactaattca cttttggccc aatttgctac
     8641 gatcgatatc attttttatt tctatatggc taaaaacgaa aagcttagcg aaaaagtgaa
     8701 aaaaacacga gaagcaatcc aagaatattt tatggattcg aaataaaaac cttactattt
     8761 tttatataag ttttttagaa taacaaaacg tagttttcca caaataaatg atccatcaaa
     8821 gtgtttcacg acttaagaaa acataatttt caaaaataag tttatttttt aatgaaaaaa
     8881 atagttggat atgtaacttt aagtgattgc tgtgaaacaa aaagttgatt ttatcttgaa
     8941 attaggtaaa gaatttcttg ctccgcccat tttttctttt ttattaagaa gtttttgggt
     9001 acaatgaagc atgaatgtaa ataggcggaa ggataggaaa tgatgaaaga ttttatgaaa
     9061 aaaatattaa atacttcttg tttattaaga agtttttggg tacaatgaag catgaatgta
     9121 aataggcgga aggataggaa atgatgaaag attttatgaa aaaaatatta aatacttctt
     9181 ggttagaaaa aataagaaaa ggtgcacaag aacctaagaa caaaacgttt cgccggtccc
     9241 atgttccttt tcgcttaaat tttctttttt tcattatatt tacgttattt gttgcgttga
     9301 ttgctagatt gggttatttg cagatcgtga acggcgaaga gatggaggcg cgagtgaagt
     9361 ctacttctac gattacggtc caagaaagta ctcctcgcgg aatgatctac gactccacag
     9421 gaaaagcttt agttacgaat aaagcgaatc aggccatcac atatacgaga ggaacacaag
     9481 ttacggctaa agatttgctt gaaatcgcaa cgaagctgaa ctcgctgatc gatgttccgg
     9541 tagatgaaaa tctgacagat agagataaaa aagatttttg gctggctgat cccaaacatt
     9601 tgaaagaagc cacaaaaaga ctttcggcaa aagaaaagca attagggaac agcgaacaat
     9661 atagtgcgat ggtcaataaa gtcacagctg atgagattaa tttaaacgag gagcaattaa
     9721 aaattgctac catctttaaa cggatgaata gtgcatatga attaaacact gtctatatca
     9781 aaaactctgg tgttactgat caagagttag ctgttgtggc agaacgcgct tctgaacttc
     9841 caggagtttc gactggcaca gactggacac gagaatataa tgcagcaagt tcactgaaaa
     9901 gtattcttgg cagtgtgacg actgaaaagc aaggacttcc agcagatgaa gcagagaaat
     9961 acctagcaaa aggttattct cggaatgacc gtgtaggaca aagttatttg gaaaaacaat
    10021 atgaagatgt cctgcaagga accaaaaccc aatatgaagt ttcccttgat aatgaaggaa
    10081 atgtttcgaa tcaaaaagaa atcttctctg gggaaaaagg ttctaattta atgttatcta
    10141 tgaatgcaga attccaatca aaagtagaag aaattttgaa aaggaattat caaacattga
    10201 tcaacaacgg caaagcacag tattcgcctg gtgcttatgc agtggctatg aatcctcaga
    10261 caggagaagt gctagcaatg actggtttca gtcatgaaca aggttccaaa gaaatcaccg
    10321 agaatgcttt aggcacgatt actagcgcct ttgatccagg gtctgtagtc aaggctggta
    10381 ctttgacagc aggctgggca agtaacgcga tcagcggaaa tcaagttttg attgatgagc
    10441 cgattcgtct gcaaggtgct tcagaaaaaa gctctgtctt taatcgaagc ggacaagttg
    10501 ctcttgatgc agtcaaagca tcggaattgt cttctaatac gtatatgatc aaagtggcgt
    10561 taaagatgtt aggactagac tatacacctg gaatgggact acctagttta gatgaagaag
    10621 ctaaagctta tcagcaattg agagactctt tcaaagagtt tggtcttggt acaacgactg
    10681 ggatcgattt gccgaatgaa tctcctggga tctcacgttc tgttgattat atgaagaagt
    10741 tcaatgcgga taatggcaaa gaatggtatg ctccaggtaa ctttaccgat ttggcatttg
    10801 gacagtttga cacatataca ccaatccaat tagctcaata tgcttcaaca gtcgctaatg
    10861 gcgggaaacg agtacagccg cacctagtca aagcgatcta tggcaatgac gaaaatggaa
    10921 acttgggtga agtgaagaaa gaaattggca caacagtaga aaatacggtc aatatttctg
    10981 cagaaaatat ggcgatcctc cgtgaaggat tccaccaagt tgtccatggt accgatcctt
    11041 acacaacagc caaaccatta gccagtgcga aaatggacct ttccgcaaaa acagggactg
    11101 cagaaacggt tgcggaaggt catccagata ttgcgacagt caatagtaat atcgtggcat
    11161 acggaccaac agacaatccg gaaattgcca tcagtgttgt cttgccgaac ttattagacg
    11221 aacaagacca cataaacttg acgattgcta aagaaataat ggacgcgtat tatgatatgt
    11281 tcatggcaaa ataaaaaaga ggtcgtgaaa aagccgctta gtttcgagta tgaagaaaaa
    11341 ttttgtgaaa atagcttctc acatttttgc ttaaatttga cttcataccg agaaactggc
    11401 ttttgaacac cgtttactcg gcaaaaaagg ttgtgacaaa aattgtcaca acct
//
LOCUS       DAFBVQ010000076        11275 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.079, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000076 DAFBVQ010000000
VERSION     DAFBVQ010000076.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11275)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11275)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11275
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.079"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(51..560)
                     /locus_tag="LLC22_002402"
     CDS             complement(51..560)
                     /locus_tag="LLC22_002402"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329381.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435650.1"
                     /translation="MKPEYLIHAEHLTVILCPLEKQHKILEHLKKEVLVAKLDNFAII
                     QKNWPMFPYLNLKDHVLLDVPEKEIKQDRLAYQEKLDISPSLLNCAAAELTSFEKVKL
                     QLLHALLSKRNNIVIEDTFDELSVLEIQELLHLLSYLAHEENQGILLFTHDATIAQSP
                     YIDRLEPAG"
     gene            complement(550..1275)
                     /locus_tag="LLC22_002403"
     CDS             complement(550..1275)
                     /locus_tag="LLC22_002403"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293939.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435651.1"
                     /translation="MKIIRYATARLIYYKKQTILYCLFSSFSAFLLIACLTLYHLQSA
                     LANQVQDRLSFIGASASTELLPALELASRFYIKGIFSLFFLFAFLFIFFFYYSVRQNK
                     QELINWHLTGLSKTKLFLFIFWQLFFPLFLCCILVLLWIVSFQSVYEALLQRINFLVL
                     KTTELPDIRDILTSVSGLTIPMDQQTFFTIDFQNDLFFTDILKGFAQTLIGLSGCCLI
                     LSLFPFTFFIHHLQSRRPGRNET"
     gene            complement(1498..3618)
                     /locus_tag="LLC22_002404"
     CDS             complement(1498..3618)
                     /locus_tag="LLC22_002404"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346400.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
                     /protein_id="HBK5435652.1"
                     /translation="MKCIKTPAFLNKRLGFFSLLVVLLWLKTIFAYLVDFHLGIESGI
                     QYFILFINPIATTLLLLGIALYIRRPRVAYITMMVIYFLLTLLVFSNVTYYREFTDFI
                     TINTILGAGKVASGLGESAIRLFRPYDVIYWIDFIILTVLLIAKKIKLDPRPIRARMA
                     FAISTLAVMIFSGNLFMAEADRPELLTRTFSRDYLVKYLGLNAFMVYDGVQTYQTNQV
                     RAEASPNDMKEVENYVKEHYAAPNDDLFGLARGKNVIYIHLESFQQFLIDYKLTDENG
                     LQHEVTPFINSLYHSNSTFSFDNFFHQVKAGKTSDAETLMENSLFGLNQGSLFTQLGG
                     KNTFQAAPDILSQTQGYISAVFHGNAGTFWNRNETYKNLGYDYFFDSSYYDVNDDNSF
                     QYGLHDKPFFQQSVQYLERLQQPFYSKFIAVSNHYPYSKFTNDEAGFPLANTNDETIN
                     GYFATANYLDTAVQEFFNYLKESGLYDNSVIVLYGDHYGVSNSRNKNLAELVGKTSST
                     WTNYDNAQMQRVPYMIHIPGQTQGGINHTYGGQVDALPTLLHLLGVDTKNYIQLGQDL
                     FSKDHEQLVSFRDGDFVTPKYTYYGGTIYSNETGEAITEPTEEVQNEIDSLKEKVDKQ
                     LAVSDQINNGDLLRFYTNSGLDPIDTSDYDYKNGLEKLKEAEKSLGDKSTSVFSEHNG
                     QSTVDLYKTQTYQELHGTTTSSSE"
     gene            3848..5026
                     /locus_tag="LLC22_002405"
     CDS             3848..5026
                     /locus_tag="LLC22_002405"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008268761.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent rRNA methyltransferase"
                     /protein_id="HBK5435653.1"
                     /translation="MKVKVKKRASNRLKKGYPLIQKEDLAHPQKETTQWVELVDSQNQ
                     FIAKGYLGKQNKGIGWVLSQQNIPFDQSFFEEFFVKSKEKRTFFFSDDSTTAFRIFNG
                     EGDGIGGLIVDYYAGYAVFSWYNETLYAHRELLIQAFREIYPEIIGGYEKIRFESVNL
                     PESQFIYGKEAPEPLIVKENGVKFAVYLNEGLMTGIFLDQKEVRGSLAEGFASGKTVL
                     NMFSYTGAFSVAAAMGGAIETTSVDLAKRSLKKTQEQFEVNGLDVDQQKIIVMDVFEY
                     FKYAKRKQFLYDMIVLDPPSFARNKKKVFRVAKDYGELVKDSLDILAEDGILIASTNA
                     ANVSIEQFQTMIEEEFHAKNVSFEQLALYRLPKDFQTTDTFLEGNYLKVFVYQIKNNH
                     "
     gene            5042..5800
                     /gene="aroD"
                     /locus_tag="LLC22_002406"
     CDS             5042..5800
                     /gene="aroD"
                     /locus_tag="LLC22_002406"
                     /EC_number="4.2.1.10"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288579.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I 3-dehydroquinate dehydratase"
                     /protein_id="HBK5435654.1"
                     /translation="MVRVKGLNIGSGRPKICAPLIGAVREEVLREAVLAREAGADLVE
                     WRVDHYREVFSFDEVAETLVLIHEMLDGLPLLFTFRTLAEGGEQDISIRQYRDLYEHV
                     IHTGLVDMVDIELFKVESLGKRLIEEIKSLNIPLIISSHDFKETPADPVLLYRLNVME
                     HFGADIGKLAVTPNNERDVLRLMELTRRANAFVSMPIITMSMGNLGKISRLVGGTTGS
                     VMTFGSLSSDSTSAPGQLPVKALKQIIQLLNEPL"
     gene            5823..6308
                     /gene="ybaK"
                     /locus_tag="LLC22_002407"
     CDS             5823..6308
                     /gene="ybaK"
                     /locus_tag="LLC22_002407"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347404.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cys-tRNA(Pro) deacylase"
                     /protein_id="HBK5435655.1"
                     /translation="MAKKKIVKTNAIRMVEQKKIPYTEHEYEWDESHLSASSVAEQLP
                     ESQSRIFKTLVAVGNVTGPLVAVIPGEAELNLKKLAKVSGNKKVEMLHLKDLEATTGY
                     IRGGCSPIGMKKLFPTYLDQIAESYEQIIVSAGRRGLQMELAPQDICALTSGQFADIK
                     Q"
     gene            complement(6379..7632)
                     /locus_tag="LLC22_002408"
     CDS             complement(6379..7632)
                     /locus_tag="LLC22_002408"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293934.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5435656.1"
                     /translation="MEKLYDVIVVGAGTSGMMAAISAAEQGARVLLIEKNKKAGKKLL
                     MTGGGRCNVTNNRPVDDLIAHIPGNGKFLYSTFAQWNNFDIMNFFESQGVHLKEEDHG
                     RMFPVTNKSKTIIEALLNRLKELDVTLLFSTRVEKLIHKEHKIYGIRTEFEEFHAPAI
                     ILTTGGRTYPSTGSTGDGYKIVKRVGHTVTPLYATESPLISDEPYIQEKTLQGLSLQD
                     ITLRVLNKKGRVLTEHTMDLLFTHFGISGPAALRCSSFVNKELEKTGEPVTLSLDCFP
                     TQTKQELIHILTEKSKATKKNLVNAWHGILPERLLVFFLERLEMDHLTGQQASQKQIQ
                     DFVQLCKEFKLSINKTFPIEKSFVTGGGVSLKEIYPKTLESKIIDGLYFAGELLDVNG
                     YTGGFNITAAFATGHVAGMNAGQRA"
     gene            7749..9098
                     /gene="gdhA"
                     /locus_tag="LLC22_002409"
     CDS             7749..9098
                     /gene="gdhA"
                     /locus_tag="LLC22_002409"
                     /EC_number="1.4.1.4"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631211.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-specific glutamate dehydrogenase"
                     /protein_id="HBK5435657.1"
                     /translation="MTNATEYVQAIQEKLHQKDQGQEEFLQAIDEFMPTVMSFLDTHP
                     EYIEKNILELLTEPERVIQFRVPWQDDEGNWRVNRGYRIQYNSAIGPYKGGLRFHPSV
                     NLSILKFLAFEQIFKNSLTGLPIGGGKGGSDFDPKGKSDNEIMRFCQSFMLELSKHIG
                     PSIDVPAGDIGVGAREIGYLFGEYKRLKKYDTGVLTGKPLDFWGSKIRTEATGYGLVY
                     YVKHLLNEEKDSFNQKTVFVSGSGNVAIYAIEKVQELGGKVVTCSDSSGYIYDPEGID
                     VKLLKEVKEINRQRLTEYANQRPSAIYHAGESVWTLKEKADIALPCATQNEIDESLAE
                     ILVENGIKIVAEGANMPCTVKAVSVLHEAGVWYCPGKAANAGGVAVSALEMSQNVQRL
                     TWEREQVDEQLDQIMETIYHTCRQTAAEYGDEKNLLLGANVAGFEKVAKAMAAEGLV"
     gene            9210..10556
                     /locus_tag="LLC22_002410"
     CDS             9210..10556
                     /locus_tag="LLC22_002410"
                     /EC_number="5.3.1.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340398.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose-6-phosphate isomerase"
                     /protein_id="HBK5435658.1"
                     /translation="MAHIHFDYSKVAPFVNEQELGYMQSQVTAAHNELREGTGAGSDF
                     RGWIDLPTNYDKEEFARIKEAAKKIQSDSEVLVVIGIGGSYLGARAAIDFLNHTFFNL
                     LDSNTRKAPQIFFAGNSISSTYIADLIEVIGDRDFSVNVISKSGTTTEPAIAFRVFKE
                     LLVKKYGQEEANKRIYATTDKAKGAVKVEADAEGWETFVIPDDIGGRFSVLTAVGLLP
                     IAVSGADIDALMQGAADASKAYSSDKLEENEAYQYAAMRNILYRKGKVTELLINYEPG
                     MQYFSEWWKQLYGESEGKDQKGIYPSSANFSTDLHSLGQFIQEGRRNIFETVVKVEKP
                     RKSITIPEQAEDLDGLGYLQGKEVDFVNTKAFEGTLLAHTDGDVPNLLVKIPEMDAYT
                     LGYTMYFFEIAVGISGYLNGINPFDQPGVEAYKKNMFALLGKPGFEDLAKELNERL"
     gene            complement(10864..11250)
                     /locus_tag="LLC22_002411"
     CDS             complement(10864..11250)
                     /locus_tag="LLC22_002411"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288573.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5435659.1"
                     /translation="MKKILGLIVIILIAFIGWKGWDYYQSTYVGKDYYAVVKAPMPAE
                     TDIKADNGEVIGRGFKYNVDAYAENGEKRQLDFDVITSGDSANGSAYPEGTILQLKAS
                     EKRIIEKKVITSDKVPSSVKEKLGLS"
BASE COUNT         3666 a         2021 c         2292 g         3296 t
ORIGIN      
        1 atcatgaatc gatcttctat accgcttgtt tttactataa aatgattgat ttagcccgcg
       61 ggctctaaac gatcaatata aggactttga gcaatagtag catcatgagt aaagagtaag
      121 ataccttgat tttcttcatg agctaaataa gaaagcaagt ggagtagctc ttggatctcc
      181 aatacactaa gttcatcaaa tgtatcttca ataacaatat tgtttcgctt ggaaagcaag
      241 gcatgaagta attgcagctt tactttttca aaagacgtca actcagctgc cgcacaatta
      301 agcaaggaag gagagatatc aagtttttct tgataggcca aacgatcttg tttgatttct
      361 ttttccggta catccaacag gacatggtct ttaagattca gataaggaaa catcggccaa
      421 tttttttgga tgatcgcaaa attatccagt tttgcaacaa gaacctcttt tttcaagtgc
      481 tccaatattt tatgctgttt ttcgagagga cacaaaataa cggtcaagtg ttcagcatga
      541 atcaaatatt caggtttcat tacgtccagg cctcctactt tgcaaatgat ggataaaaaa
      601 agtgaaaggg aatagactaa gaatgagaca gcatccactg agcccaataa gagtttgggc
      661 aaatccctta agtatatctg tgaaaaaaag atcattttgg aaatcgatgg taaaaaaagt
      721 ctgttgatcc atcggaattg taagtccgct taccgaagtc aagatatcac ggatatctgg
      781 cagttcagta gtctttaaga caagaaaatt gatcctttga agaagcgctt cataaactga
      841 ctggaagctt acgatccaca ataaaaccaa gatacaacaa agaaagagag gaaagaacag
      901 ctgccagaaa ataaaaagga ataatttggt tttagaaaga ccagtcaggt gccaattgat
      961 caattcctgc ttgttttgcc tgactgaata gtaaaagaaa aagataaaaa ggaaggcaaa
     1021 tagaaaaaat aaactgaata tgccttttat ataaaatcgg ctagctaatt ctaaagccgg
     1081 aagaagctct gtagatgcag aagcgccaat aaatgaaagc cgatcttgga cttgattggc
     1141 taaagccgat tgcaaatggt aaagagtcag gcatgctatc aataaaaaag cagaaaagct
     1201 tgaaaataaa caatagagta ttgtctgctt tttgtaataa attaatcgag cagtagcata
     1261 gcggattatt ttcatacttt tcacctctat aaaaagtata gaaaatgaat atgaataaag
     1321 tatgaaattc ctttagtgaa atcacgaatt aaaaccagaa aatattttgt aaaaagcaag
     1381 aggttgtgaa gaagctgccc tattctatta ccgtagatgc aagcttttga acactgttta
     1441 ttcgaaaaga ggagcagcga caataatttt gtcgctgctc cttttaaatt tattttatca
     1501 ttcggaagaa cttgtggtcg ttccgtgaag ttcttggtac gtttgcgttt tataaagatc
     1561 aacagttgat tgtccgttgt gttcactaaa gacactagtt gacttgtcac caagagattt
     1621 ttcagcttct tttaatttct ctaagccatt cttgtagtca taatcactgg tatcaattgg
     1681 gtctaatcca ctattcgtat agaaccgaag aagatcacca ttattgattt ggtcagaaac
     1741 agctaactgt ttatcaactt tttctttcag tgaatcaatt tcattctgta cttcctcagt
     1801 aggttcagta atagcttcac cagtttcgtt actatagatc gtaccaccgt agtaagtata
     1861 ttttggtgta acaaaatcac catcacggaa agaaacaagc tgttcatgat ctttcgagaa
     1921 tagatcttgt cctaactgaa tataattttt tgtatctaca cctagtaagt gaagtaatgt
     1981 aggcaaggca tcaacttgtc cgccgtaagt gtgattgatt ccgccctgtg tttgtccagg
     2041 gatatggatc atataaggga cacgctgcat ttgtgcattg tcgtagtttg tccaagtaga
     2101 acttgttttt ccaactaatt cagctagatt tttatttctt gaattcgaga caccgtaatg
     2161 gtcaccgtaa aggacgatga ctgaattatc atacaagccg ctttctttca aataattgaa
     2221 gaattcttgt acggcggtat ctaaataatt ggctgtcgca aagtaaccgt tgatcgtttc
     2281 atcatttgta ttggctaacg ggaatcctgc ttcgtcattg gtgaattttg aataaggata
     2341 atggttagat acagcaatga attttgaata aaatggttgt tgcagacgtt ccaagtattg
     2401 tacggattgt tggaaaaatg gtttatcatg caacccgtat tggaacgaat tgtcatcatt
     2461 aacatcataa taagaagaat caaagaaata atcatatcct aaattcttgt atgtctcgtt
     2521 tcgattccag aatgtaccag cgttcccatg gaataccgca ctaatgtaac cttgtgtttg
     2581 acttaaaata tcaggtgcag cttggaaagt attttttccg cctaattgtg tgaacaagga
     2641 gccttgattc aagccaaaca atgaattttc catcagcgtt tccgcatcgc ttgtttttcc
     2701 tgcttttact tgatggaaaa agttgtcaaa actgaacgtg ctgttgctgt ggtaaagact
     2761 attgatgaaa ggtgtaactt catgctggag accattctca tctgtcaatt tataatcgat
     2821 caggaattgc tggaagcttt ctaaatggat ataaatcaca ttttttcctc tagcgagccc
     2881 gaacaaatcg tcatttggtg ctgcataatg ttcttttaca taattttcta cttctttcat
     2941 atcattggga cttgcttctg cccgcacttg gtttgtctgg taagtttgaa caccgtcata
     3001 aaccatgaaa gcattcaagc caagatattt gaccaaataa tcacgagaga atgttcgagt
     3061 cagcaattct ggacgatcag cttccgccat aaaaagattt cctgagaaaa tcataactgc
     3121 taatgtagag atcgcaaaag ccattcttgc tcggatcggg cgagggtcca acttgatttt
     3181 ttttgcaatc agcagaacag tcaagataat aaaatcgatc caatagatca catcatatgg
     3241 gcgaaacagt cgaatggcac tttctcccag accactcgct actttcccag cacctaaaat
     3301 cgtgttgatc gtaatgaagt ccgtgaattc tcgataataa gtgacattcg aaaaaacaag
     3361 caatgtcaaa agaaaataaa tgaccatcat cgtgatataa gcaactctag ggcgtctgat
     3421 ataaagagca attccaagta ataacaatgt agttgcaata gggttgataa acaagataaa
     3481 gtattgaatg ccactttcga ttccgagatg gaaatcaact aaataggcaa aaatcgtttt
     3541 caaccaaagt aaaacgacta gtaaagaaaa aaatccgagc ctcttattca aaaaggcagg
     3601 tgtttttata catttcaaga taatcttcct ttctgcactt cttaatcaca gaagtgtcct
     3661 gaaaccatgt tacacagctc acttattctc atttatttta ctagtatgac aatatagtgt
     3721 caattgaaac cagaagttta tgctgtttca ttaaggtttt ctttaagctt catgaaaaaa
     3781 tgagcagtaa gacaagtcct atgttttttg ttatacttgg gaagagaaag ctaaagcagg
     3841 tgaaggaatg aaagtaaaag taaaaaaaag agcaagcaat cgattgaaaa aaggatatcc
     3901 actgatccaa aaagaagacc ttgctcatcc ccaaaaagaa accacgcaat gggtggaatt
     3961 agttgattcg caaaaccaat ttatcgcaaa aggatatcta ggaaagcaga ataagggaat
     4021 cggttgggta ttgagccagc agaacatccc atttgatcaa tctttttttg aagaattttt
     4081 tgtgaagtca aaagaaaaaa gaactttctt tttttcagat gattctacta ccgcttttcg
     4141 tatattcaat ggagaaggag acgggatcgg cggtctgatt gttgattatt atgcaggtta
     4201 tgctgttttt tcttggtata acgaaacgtt atatgcacat cgtgaattat tgattcaagc
     4261 ttttcgtgaa atctacccgg aaatcatagg aggctatgag aaaattcgat ttgaatcagt
     4321 aaatctgcct gagagccagt tcatttacgg aaaagaggca ccggaaccct tgatcgtaaa
     4381 agaaaacgga gtaaaatttg ccgtttattt aaatgaagga ttaatgactg ggatcttttt
     4441 agaccaaaaa gaagtacggg gatcattagc agaaggtttc gcttctggga aaacagtttt
     4501 gaacatgttt agttataccg gcgccttttc tgttgctgcc gcaatgggag gggcaatcga
     4561 aacaacaagt gtcgatctag caaaacgcag tttaaaaaaa acacaggaac agtttgaagt
     4621 gaatggtttg gatgtcgatc agcaaaaaat cattgttatg gacgtattcg agtatttcaa
     4681 atacgccaaa agaaaacaat ttttatatga catgattgta ttggatccac caagttttgc
     4741 cagaaataag aaaaaagtct ttcgcgtagc aaaagattat ggggaactgg tcaaggatag
     4801 tctggatatt ttagcagaag acgggatact tattgcgtct acaaatgctg cgaatgtctc
     4861 gatagaacaa ttccaaacaa tgattgaaga ggaattccat gccaaaaatg tttcttttga
     4921 acaacttgct ttatatcgtc tgccaaaaga tttccagacg acggatacct ttttagaagg
     4981 caattatctg aaagtgtttg tttatcaaat taaaaataac cattagaagg agcgatgcag
     5041 aatggttcgg gtaaagggat tgaatatagg aagcggtaga ccaaagattt gtgcgcctct
     5101 tatcggggcc gtccgagagg aagtattacg tgaagcagtt cttgcacgtg aagcaggggc
     5161 cgatttagtc gaatggcgag tcgatcatta tcgtgaagtt ttttcttttg atgaagtagc
     5221 agaaacattg gttcttatcc atgagatgct tgatggactg ccgttattat ttacgtttcg
     5281 taccttagct gaaggcggag aacaagacat atcgatccgt cagtatcgcg acctttatga
     5341 acatgtgata cacacaggat tagtagatat ggtcgatatc gagttgttca aagtagaaag
     5401 tctaggaaaa agactgatag aggaaatcaa gtctttaaac attcctttaa ttatcagtag
     5461 tcatgatttt aaagaaacac cagcagaccc tgtcttgctt taccgattga atgttatgga
     5521 acattttgga gccgatatcg gaaaactggc agtaactccc aataatgaac gagatgtttt
     5581 gcggttgatg gagttgacta gacgggcaaa tgcttttgtc tccatgccta ttattacgat
     5641 gtccatggga aatcttggta aaatttctcg tctggttggc ggaacgacgg gttccgttat
     5701 gacatttggt tccttaagca gcgattctac ttctgctcca ggacaattac cggtcaaagc
     5761 attgaagcaa attattcaat tattaaatga accgttgtag aacaagtttg aggtgatatt
     5821 ttttggcaaa gaaaaaaata gtaaaaacga atgcaatccg tatggtcgaa caaaaaaaga
     5881 ttccctatac agagcacgaa tatgagtggg acgaaagcca cctaagtgcg tcatcggtcg
     5941 ctgaacagct tccagaaagc caatctcgta tatttaaaac actggttgct gtgggcaatg
     6001 tgacggggcc tcttgttgct gtgataccgg gagaagccga attgaatcta aaaaaattag
     6061 caaaagtttc agggaataaa aaagtagaaa tgctccattt aaaagatttg gaagcaacga
     6121 ccggatacat acgtggtggc tgctcgccta taggtatgaa aaaactattt cctacttatt
     6181 tagatcaaat tgcagaaagc tatgaacaaa tcattgtctc ggctggcaga agagggctac
     6241 agatggagtt agcacctcaa gatatctgtg cattaacgag cggacaattt gcagatataa
     6301 aacaataaat catacgtata aaagaaagaa ggaggccggg atgttgtttg tccagtctcc
     6361 ttctttcttt tttatacatt atgctctttg cccggcattc attcctgcta catgccctgt
     6421 agcgaaagcc gctgtgatat taaagccgcc agtataacca ttgacatcca gtaattctcc
     6481 cgcaaaatac agaccatcaa tgattttact ctccaatgtt ttaggataaa tttcctttag
     6541 agaaacccct ccgccagtta caaatgattt ctcaatagga aaagttttgt tgattgatag
     6601 cttaaactct ttgcatagtt gaacaaaatc ttgaatttgt ttttgagagg cttgttgtcc
     6661 tgtcagatga tccatttcaa gccgctcaag aaagaaaact aacaatcgct caggcaatat
     6721 accatgccaa gcattgacca agttcttttt ggttgcttta cttttttctg tcaatatatg
     6781 aataagctct tgtttggttt gtgtagggaa acaatccaga gaaagtgtca ctggttctcc
     6841 cgttttctct aattctttat tgacaaaact tgaacaacgc agtgcagccg gaccagaaat
     6901 accgaaatgg gtgaaaagta aatccatcgt atgttcagtc aatacacgac cttttttatt
     6961 taaaacgcgt aaagtgatgt cttgtaaaga aagcccttga agtgttttct cctgaatata
     7021 cggttcatcc gatatcaagg gggactctgt cgcataaaga ggcgtcaccg tgtgacccac
     7081 tcgcttcacg atcttgtacc catctccagt agaaccagta gatggataag tccgtccacc
     7141 agttgttaag ataatggcag gagcatggaa ctcttcgaat tccgtgcgta taccgtaaat
     7201 tttatgttct ttgtggatca atttctctac tcgagtagag aatagaagcg tcacatctag
     7261 ttctttcaga cgattgagca atgcttcgat aatcgttttt gatttatttg ttacaggaaa
     7321 catccgtcca tgatcctctt cttttaaatg tacgccttgt gattcaaaga agttcatgat
     7381 atcgaaatta ttccattgcg caaacgtact atataaaaac tttccatttc caggaatatg
     7441 tgcaatcaaa tcatcaacag gacgattgtt cgtaacattg caccgaccac cacctgtcat
     7501 cagtagtttt tttcctgctt ttttgttttt ttcgatcaag agtacgcgtg cgccttgttc
     7561 agctgcactg atcgctgcca tcatcccgct tgttccagcg ccgactacga tcacatcata
     7621 cagtttttcc attccctcac ctcaaggaaa gtgtagcata tctgaagaaa gaaaacagaa
     7681 aaaaatgttt tgagccaaaa gagaaaatga gctaaaatga gggaagataa gcaaaggagc
     7741 gtggaacgat gacaaacgca acagaatatg ttcaagcaat tcaagaaaag ctacatcaaa
     7801 aggatcaagg gcaagaagaa tttttacaag caatcgatga attcatgccc acggttatgt
     7861 cttttttgga cactcatccc gaatatatcg aaaagaatat cttagaactt ttaacggaac
     7921 cagaaagagt tattcaattt cgagtgcctt ggcaagatga tgaaggaaac tggcgagtaa
     7981 atagagggta ccgtatccaa tacaactcag ctatcggccc ttataaaggt ggattgcgct
     8041 tccatcctag tgtcaatcta agtatcttga aatttttggc ttttgaacag attttcaaga
     8101 atagtttaac cggtctgcca atcggtggag gaaaaggcgg aagtgacttc gatcctaaag
     8161 gaaaatctga taatgagatc atgcgttttt gtcaaagttt catgctggaa ttgtcaaaac
     8221 atatcggccc atcgattgat gttcctgcgg gagatatcgg tgtaggagct agagaaatcg
     8281 gctatttgtt cggcgaatat aaacgattga aaaaatatga tactggtgtg ttgacaggta
     8341 aacctttgga tttttgggga agtaagatac gtacggaagc tactggttat ggattagtgt
     8401 attatgtcaa acatctattg aacgaagaaa aagattcatt taatcaaaaa acagtttttg
     8461 tttccggaag cgggaatgta gccatttatg caatcgaaaa agtgcaagag ctaggcggga
     8521 aagttgttac atgttcagat tctagcgggt acatctatga tccagaagga atagatgtga
     8581 aactattgaa agaagtcaaa gaaatcaata gacaacgttt gacggaatac gcaaaccaac
     8641 gtccttctgc tatttatcat gctggagaat ctgtttggac attgaaagaa aaagcggata
     8701 tcgctttgcc atgtgctact caaaatgaaa tagacgaaag cttggccgaa atcttagtag
     8761 aaaatgggat caaaatcgta gcagaaggcg ctaatatgcc atgtacagta aaagctgttt
     8821 ctgttcttca tgaagcaggc gtgtggtatt gtccaggaaa agctgctaat gctggaggag
     8881 tagcagtatc tgctttagaa atgagtcaga acgtccagcg attgacttgg gaaagagagc
     8941 aagtggatga gcagctggat caaatcatgg aaacgattta ccatacgtgt cgccaaacag
     9001 cagccgagta cggcgacgaa aaaaatctgc ttcttggagc aaatgttgct ggatttgaaa
     9061 aagttgccaa agcaatggca gcagaaggtt tagtttgaaa aatgaaactt tcttggaaat
     9121 attgtcagca ttttgtttat ttgcttgaaa aataataaaa aaaaacgtaa agtattacct
     9181 gtagagtaaa cctataagga ggagaacaaa tggcacacat tcattttgac tattcaaaag
     9241 tagcaccgtt tgtcaacgaa caagagttag ggtacatgca aagccaagta acagcagccc
     9301 acaacgaatt acgggaaggt actggcgcag gaagcgactt ccgcggctgg atcgatttac
     9361 caacgaacta tgacaaagaa gaatttgcac gtatcaaaga agcagctaaa aaaatccaat
     9421 ctgattctga agtattagtt gttatcggta tcggtggttc ttatttaggc gctcgtgcag
     9481 cgatcgactt cttgaatcac acattcttca atttattaga tagcaacaca agaaaagcac
     9541 cacaaatctt ctttgccgga aattcaatca gctcaacata tattgctgac ttgatcgaag
     9601 taatcggtga tcgcgacttt tcagtaaacg ttatttcaaa atctggaaca actactgaac
     9661 cagcgattgc gttccgtgta ttcaaagagc ttcttgttaa gaaatatgga caagaagaag
     9721 caaacaaacg tatctacgct acaacagata aagcaaaagg tgcagttaaa gtagaagcag
     9781 atgcagaagg ttgggaaact ttcgtgattc ctgatgacat cggcggacgt ttctctgtat
     9841 taactgctgt tggtttgtta ccaatcgctg ttagtggtgc agatatcgat gcattgatgc
     9901 aaggtgccgc tgatgcaagc aaagcatact caagcgacaa actagaagaa aacgaagctt
     9961 accaatacgc agcaatgcgc aacattcttt accgtaaagg caaagtaact gagttgttga
    10021 tcaactatga accaggaatg caatacttct cagaatggtg gaaacaattg tatggtgaat
    10081 ctgaaggaaa agaccaaaaa ggcatctatc cttcaagcgc aaacttctca actgatttgc
    10141 actctttagg acaattcatc caagaaggac gtcgcaatat ttttgaaaca gttgtgaagg
    10201 ttgaaaaacc tcgtaaatca atcacaattc ctgaacaagc agaagattta gacggtctag
    10261 gctacttgca aggaaaagaa gtggacttcg taaatacaaa agcatttgaa ggaacattgc
    10321 ttgctcatac agacggtgac gtgcctaact tgctagtcaa aattccagaa atggatgctt
    10381 atacattggg ttatacaatg tacttctttg aaattgctgt aggtatttca ggttacttga
    10441 atggaatcaa cccattcgac caaccaggtg tagaagctta caagaaaaac atgttcgcac
    10501 ttctaggcaa accaggcttt gaagatcttg ctaaagaatt gaacgaacgc ctgtaagata
    10561 agggtttttc gctagattta aataatcagt gatagaaaca tgttcgcttt aaaatgaaaa
    10621 ctggtaccca tttaggtact caaacatact gcatcgttta ttcagaataa ggggctgtga
    10681 caagacgttt gtcacagtcc cttgtttgta tagaaatcga ttgattgcct tgctctttag
    10741 tttgttttag gactttaaga acagtgaggc tgacttcgaa ggttaattct gtttttttgt
    10801 tttctagaat cagtaagcaa aaaagcactc acttcgagtg cttttttgcg atatattctt
    10861 agcttaagat aggcctaatt tttcttttac agatgagggt accttatcgc tggtaattac
    10921 ttttttctct atgatccgct tttcgcttgc tttcaactgc aagatcgttc cttcggggta
    10981 agcagaacca ttggcagagt caccagaagt aatgacatcg aaatctaact gtcttttttc
    11041 accgttttca gcataagcat ctacgttgta tttaaaacct cttccaatta cttccccatt
    11101 atctgctttg atatcagttt ctgcaggcat tggagctttg actaccgcat aataatcttt
    11161 acctacataa gtagactgat agtagtccca acctttccat cctataaaag caatcaatat
    11221 gataacgatc aaccctaaaa tttttttcat gaaagatctc cttttttatt tttat
//
LOCUS       DAFBVQ010000077        11255 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.080, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000077 DAFBVQ010000000
VERSION     DAFBVQ010000077.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 11255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 11255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..11255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.080"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LLC22_002412"
     CDS             complement(17..1246)
                     /gene="hflX"
                     /locus_tag="LLC22_002412"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324580.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GTPase HflX"
                     /protein_id="HBK5435660.1"
                     /translation="MEEKVIIVGVETEANQRYFSESMEELVQLTNTASGEVVFTITQK
                     RPQVDRQTIIGKGKLQELVQQADAHEADLIIFNHELTPRQSQLITDAVGLPVIDRVQL
                     ILDIFAMRARSKEGKLQVELAQLEYLLPRLVGQGKTLSRLGGGIGTRGPGETKLETDR
                     RHIRNKIFAVKKELKEVEAHRERNRQKRKNSEIFQIGLIGYTNAGKSTILNLLTQADT
                     YSKDQLFATLDPLTKRWRFAEGFEITVTDTVGFIQDLPTQLIDAFHSTLEESQNMDLL
                     LHVVDASSPDRILQEQTVLKLMDELNMKEMPILTVYNKADQIDPAMFTPTLFPNVLIS
                     TQTKEGKMALIEAIKRQLMELMTPYTLSVPSNEGQKLSELRRQTMVLDEAYMEETNEY
                     EVKGFAKTNSKWLRKNQ"
     gene            complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LLC22_002413"
     CDS             complement(1248..2165)
                     /gene="miaA"
                     /locus_tag="LLC22_002413"
                     /EC_number="2.5.1.75"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391642.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA (adenosine(37)-N6)-dimethylallyltransferase
                     MiaA"
                     /protein_id="HBK5435661.1"
                     /translation="MEKVLVIVGPTAVGKTALSVELAQLFGGEIISGDSLQIYKNLDI
                     GTAKIKEEEMNNVPHHLIDVIEPTQRYSAADFQHSGRQLITEIANRGHLPIIAGGTGL
                     YIQSLLYDYQLGATEEANPEIRKKYETLAETIGSQALWNQLKEKDPAAAEKIHWNNQR
                     KVIRALEVLETTGHSITAPKEEPKQLYDYLMIGLDTKRSILYERINQRVDLMLAEGLV
                     AEARKVYELGEVQASQGIGYKEFFPYFEGKETLEEATEQVKLHSRRYAKRQLTWFRNR
                     LDAQWFDLISEPNQKSQIEQTIKKWLEAE"
     gene            complement(2169..2906)
                     /locus_tag="LLC22_002414"
     CDS             complement(2169..2906)
                     /locus_tag="LLC22_002414"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628886.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBK5435662.1"
                     /translation="MLQIYAHRGSSGTHPENTLPAFAEAVRVGADGIELDVHLSKDGY
                     LIVMHDEEVDRTTNGKGLIREKTLEELKKLNAGGKFSKEFPAAKVPELREVLGLLLQK
                     NYRGMLMIEIKTDQYEYPGIEEKLAETLKSRDWPFQHAYCSFHLDSLEKIALLEPEIQ
                     LDLLMSTSDKKIQLAAETPYIEGVHPKNTWLFEHPVQAADFPKAIRAWTINDEEEMAK
                     CQELKIDGIITDFPEKALRWKQSTKSR"
     gene            complement(2997..3524)
                     /locus_tag="LLC22_002415"
     CDS             complement(2997..3524)
                     /locus_tag="LLC22_002415"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752644.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435663.1"
                     /translation="MIVGITGLIGVLTGAVVVYIGMILQMRHLENKEQRRRELELKVK
                     EIETLNQLNKKINEILQKRTTLMEEYVSFDAFDDCYITIDDFAYLQSFSAQNSFYLPN
                     YILDELFKNISHRKVILSPDETMKIGGYAYKGGRVILENFTDSLTEMINEKKAQLKTM
                     TRQPIGFFSKDDVWS"
     gene            3704..4297
                     /gene="clpP"
                     /locus_tag="LLC22_002416"
     CDS             3704..4297
                     /gene="clpP"
                     /locus_tag="LLC22_002416"
                     /EC_number="3.4.21.92"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp endopeptidase proteolytic
                     subunit ClpP"
                     /protein_id="HBK5435664.1"
                     /translation="MNLIPTVIEQSSRGERAYDIYSRLLKDRIIMLSGQVTDDLANSI
                     IAQLLFLDAQDSEKDIYLYINSPGGSVTAGMAIYDTMNFVKADVQTIVMGMAASMGSF
                     LLTAGTKGKRFALPNAEIMIHQPLGGAQGQATEIEIAARHILQTRERLNKILAERTGQ
                     PLEVIEKDTDRDNYMTAEQAKAYGLIDEVMENSSSLN"
     gene            complement(4401..4886)
                     /locus_tag="LLC22_002417"
     CDS             complement(4401..4886)
                     /locus_tag="LLC22_002417"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008267279.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="gamma carbonic anhydrase family protein"
                     /protein_id="HBK5435665.1"
                     /translation="MERFIASNATVIGDVTLSEDVTIWYQAVLRGDSNWIKIGQRTNI
                     QDGTIIHVDHDAPVDIAENVTVGHQCMLHGCTIEKGALIGMGTTILNHAVIGENSLIG
                     AGSLVTEGKVIPPNVLAFGRPAKVIRPLTKEEIQKNKENIQHYVEIGRMHAQGKFKEQ
                     R"
     gene            complement(5039..5236)
                     /locus_tag="LLC22_002418"
     CDS             complement(5039..5236)
                     /locus_tag="LLC22_002418"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296291.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435666.1"
                     /translation="MEQFLNEKITEAKREVDRLTHVCQTKPFDSADFFENEFQIERLA
                     AQIEVYELILKKVIEENIDVQ"
     gene            complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LLC22_002419"
     CDS             complement(5331..7091)
                     /gene="efrB"
                     /locus_tag="LLC22_002419"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_029485765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrB"
                     /protein_id="HBK5435667.1"
                     /translation="MKKTFSSLKRLARYIRPYRETFLLVILFTVLTVAFNVALPYVTG
                     LPTTEISRNIANGESINFSYIFKCLIWITVVGIGYCISQLLSGVLMTNVVQSAMHDLR
                     RDIEEKINRLPVSYFDKNQQGNILSRVTNDVDAVSGALQQAFIGIVNAILGITLAAAM
                     MFYIQPMMALISMIMIPTSIWISKRVINASQKYFQSMQNSLGELNGYVQENMTGFSVL
                     KVYGREKETLEGFKKVNHSLKYFGFRAAFISGLMMPLVQLTAYATYIGMAVLGSFYVI
                     TGAIVVGQLQAFIQYIWQISQPMGNVTQLSSVLQSASAATKRVFEILDEPEEKENKVD
                     ASLPETILGDVTFDHVDFAYDPKKPLIQDLNFEVKAGQTVAVVGPTGAGKTTLINLLM
                     RFYDVDKGAIRIDGIDTKSMSRSDVRSLFGMVLQDAWLYQGTIADNIRFGKLDATDYE
                     VVDAAKTANVDHFIRTMPDGYDMAINSEGDNVSLGQKQLLTIARAVVSDPKILILDEA
                     TSSVDTRLEALIQKAMDRVMEGRTSFVIAHRLSTIRDADLILVMDQGQIIEKGTHESL
                     LAQGGFYEKLYNSQFAEEAE"
     gene            complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LLC22_002420"
     CDS             complement(7088..8818)
                     /gene="efrA"
                     /locus_tag="LLC22_002420"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux ABC transporter subunit EfrA"
                     /protein_id="HBK5435668.1"
                     /translation="MKLMWHYTMRYKKFLFFNFICVFGFILIELGLPTILARMIDVGI
                     RNDDFDYVKQQGIFMIVITVIGIILNILLGYFGSRITTNIVADIRDDLFEKIQSYSHQ
                     EYENLGVSSLITRTTNDAYQIMLFLQNILRIGFMAPMMFIVSLYMVMRTSVTLSLYVV
                     GALPLLLLAVVAIAKVSEPLSKKQQKNLDKINSILRENLSGLRVIRAFVNEKFEEKRF
                     AVVNENYASSSKSLFRLMAVAQPGFYFLFNIVMVLIIWSGAVQIDAGELRVGDLIAFI
                     EYIFHALFSFMLFASVFMMYPRAAVSAGRIQEALDAKPSIVEDPNGISDTKTKGYIEF
                     QNVTFAYPGHSQEPVIRNVSFTASPGETVAFIGSTGSGKSTLIQLIPRFYDVSEGKIL
                     IDGVDVRDYRLSKLRDKIGFIPQKALLFTGTIADNLRYGKEDATQEEMERAAEIAQAS
                     EFISRKPDGFNEHLSEGGSNFSGGQKQRLAIARAIIRRPEIYIFDDSFSALDYQTDAK
                     LRARLKKETTESTVLIVAQRVGTIMHADKIIVLNEGEVVGMGTHRELLEKCPIYYDIA
                     ASQLSKEELA"
     gene            9211..9423
                     /locus_tag="LLC22_002421"
     CDS             9211..9423
                     /locus_tag="LLC22_002421"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010736074.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-dependent RNA polymerase auxiliary subunit
                     epsilon family protein"
                     /protein_id="HBK5435669.1"
                     /translation="MIYKVYYQETKVRNPKREETKSLYIEAKSDVDARQRVEENTPYN
                     IEFVQLLEGSHLEYEKENADFSLVEF"
     gene            9425..11104
                     /locus_tag="LLC22_002422"
     CDS             9425..11104
                     /locus_tag="LLC22_002422"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribonuclease J"
                     /protein_id="HBK5435670.1"
                     /translation="MKLSIKNNETGVFAIGGLGEIGKNTYGVQFQDEIILIDAGIKFP
                     EDDLLGIDYVIPDYSYIIQNLHKVKALVITHGHEDHIGGIPYLLKQANIPIYAGPLAL
                     ALITNKLDEHGLLRDAELHEINEDTIIRFRKTSVSFFRTTHSIPDALGIVVKTPSGNI
                     VATGDFKFDFTPVGEPANLHKMARIGEEGVLCLLSDSTNAEIPTFTKSEKTIGHSILK
                     IFSKIEGRIIFASFASNIFRLQQAADAAVATGRKIAVFGRSMENAIVNGQRLGYIKVP
                     DGTFVDAHEINRLPANETMILCTGSQGEAMAALSRIANGTHRQIQIQPDDTVIFSSSP
                     IPGNTTSVNHLINLLSEAGAEVIHGKINNIHTSGHGGQEEQKLMLRLMKPKYFIPVHG
                     EFRMLKVHASLAQDVGVPAENCFIMENGDVLALTSDSARPAGHFVAGDVYIDGSGIGD
                     IGNVVLRDRHLLSEEGLVLAVATVDIKKKEILAGPDILSRGFVYMRESGEMINEAQRI
                     LFHALRECLNGPDCSEYKLKEAMTGALQPFLFERTERHPMILPMVMTPDEE"
BASE COUNT         3266 a         2429 c         1971 g         3589 t
ORIGIN      
        1 ttaaaaaaat aaaattttat tggttttttc ttaaccattt tgaattggtt tttgcaaacc
       61 ctttaacttc atattcgttt gtttcttcca tgtacgcttc gtccaaaacc attgtttgtc
      121 ttctcaactc gcttaatttc tgtccttcgt tgcttggcac agaaagtgta taaggggtca
      181 ttagttccat cagctgacgt ttgattgctt cgatcaacgc catcttacct tctttcgtct
      241 gagtagaaat caatacattt gggaatagcg taggcgtgaa catcgctggg tcgatctggt
      301 ctgccttatt gtaaacagtc agtatcggca tttctttcat attcagttca tccatcaatt
      361 ttaagacagt ctgctcctgt aaaatacgat ctggagaact agcatcgact acatgtagca
      421 aaagatccat attttgactt tcttctaatg tagaatggaa agcatcgatc agttgcgtag
      481 gcaggtcttg gatgaacccg acggtatccg ttacagtaat ctcaaatcct tcagcaaaac
      541 gccatctctt agtcaatgga tctaacgttg caaacaattg atctttcgaa taagtatccg
      601 cttgtgtcaa tagattcaag atagttgact tcccggcatt cgtgtagcca ataagtccaa
      661 tctgaaaaat ctcgctattt tttctttttt ggcgattgcg ctctcgatga gcttctactt
      721 ctttcaattc tttcttaaca gcaaaaattt tattccgtat atgtcggcgg tctgtttcta
      781 actttgtttc acctggccct cttgttccga tcccaccgcc aagacgagat aatgttttcc
      841 cttgccctac taaacgaggc agcaggtatt ctaactgagc aagttcaacc tgcagcttcc
      901 cttctttcga acgagcacgc atcgcaaaaa tatctaagat aagctgcacg cgatcaatta
      961 ccggaagacc aacagcatcg gtaatcagtt ggctctgtct cggagttagc tcatgattaa
     1021 agatgatcaa atccgcttca tgcgcatccg cttgttgaac taattcttgt aatttccctt
     1081 taccgataat cgtttgccga tccacttgtg gtctcttttg tgtaattgtg aatacgactt
     1141 ctcctgatgc ggtattcgtc agctgaacta gctcttccat tgactctgaa aagtaacgct
     1201 ggtttgcttc ggtttctacc cctacgatga tcactttttc ttccatttta ttccgcctcc
     1261 agccattttt tgattgtttg ctcaatctga cttttttgat ttggctcact tataagatca
     1321 aaccactgtg catccaaacg gttacgaaac cacgtcaact gacgtttcgc gtatcttctc
     1381 gaatgtagtt tgacttgttc tgttgcttct tccaatgttt ctttcccttc aaaataaggg
     1441 aaaaattctt tatatccaat accttgactg gcctggactt ctccaagctc atacacctta
     1501 cgcgcttctg ctactaaacc ttctgctagc atcaaatcga ctctttgatt gattcgttca
     1561 taaagaatac tacgcttcgt atctaatcca atcatgaggt aatcatacaa ttgctttggc
     1621 tcttctttag gtgccgtgat actatgtcct gtcgtctcta aaacttccag agctcttatc
     1681 actttgcgtt gattgttcca gtggattttc tcagcagctg ccgggtcttt ttctttcaac
     1741 tgattccata atgcttggga accaattgtt tcagctaacg tttcatactt ttttctaatc
     1801 tcaggattcg cttcttctgt cgctcctaac tgataatcat atagaaggga ttggatatag
     1861 agacccgtac caccagctat gataggtagg tgccctcggt tcgcaatctc ggtaatcaat
     1921 tgtcgacctg aatgctgaaa atcagcggct gagtaacgtt gagtaggttc gatcacatca
     1981 atcaaatgat gcggaacatt attcatctct tcttctttga tttttgctgt accgatatcc
     2041 agatttttat agatttgcaa tgaatcacca ctgatgatct ctcctccaaa tagttgtgcg
     2101 agttccacac ttagcgctgt tttaccgact gctgtcggac cgacgatcac taatactttt
     2161 tccatatttt acctactttt cgttgattgt ttccaccgaa gagctttctc cggaaaatca
     2221 gttattattc catctatttt gagttcttga catttggcca tttcttcttc atcgttaatc
     2281 gtccatgcac gaattgcttt tggaaaatca gctgcctgga ctggatgttc gaacaaccaa
     2341 gtattttttg gatgtactcc ttctatataa ggggtttctg ctgctagttg gatcttttta
     2401 tcagaagtac tcatcaataa gtccagctgt atctccggtt ccagtaatgc gattttttcc
     2461 aaagaatcca aatgaaagct gcaatatgca tgttgaaaag gccaatctct actttttaat
     2521 gtttcggcta atttttcttc gataccggga tattcatact gatcagtttt aatttcaatc
     2581 attagcatcc ctcggtaatt tttttggagg agcagtccta acacttctct caattcagga
     2641 actttagctg ctggaaattc tttgctgaat ttgccccctg cattcaattt tttgagttct
     2701 tccaatgttt tttctcgaat cagcccttta ccgttagtcg tccggtccac ttcttcgtcg
     2761 tgcataacga tcaaataacc atctttgctt agatggacat ctagttcgat accatctgca
     2821 cctactcgta cagcttctgc aaatgcagga agcgtatttt ctgggtgggt gccgctgctt
     2881 ccgcgatggg catagatttg taacatcttt cttcactccg ttcagttcta ttgtatcatt
     2941 aagaaaaaaa gaaagcatta ccacgctctc atgtgcaacg gcaatgcttc aaaatatcag
     3001 ctccaaacat catctttcga gaagaaacca atcggctggc gcgtcatagt cttcaactga
     3061 gctttttttt cattgatcat ttcagtcaga ctatccgtaa aattctctaa aatcacgcgt
     3121 ccgcctttat aagcatatcc accaatcttc attgtttcat ctggagataa aatcactttt
     3181 cgatgggaga tattcttaaa tagctcgtct aaaatataat ttggcagata aaaactattt
     3241 tgcgctgaaa atgattggag atacgcaaaa tcgtcaatcg tgatataaca atcatcaaat
     3301 gcatcaaagc tgacatattc ttccatcagc gttgtccgtt tttgcaagat ctcgttgatc
     3361 tttttattta attgattcag cgtctcgatt tctttgactt tcaattccaa ttcacgtcta
     3421 cgctgttctt tattttccaa gtgacgcatt tgcagtatca tgccgatata gacaactaca
     3481 gcacctgtca gcactccgat aaggccagta ataccaacta tcaatctgtt gttcctcctt
     3541 gttttgtttc tctgcttatc ataccataaa gcgggtttat gcgactaatt tgcctaagtt
     3601 ttttatttga ccttttttga ccaaaaatgt atactacatt ttaggtatta gaaactaaat
     3661 tatggtacac tatttctaaa cgaaatcaag gaggaactct attatgaatt taattcctac
     3721 agtcattgaa caatcttcac gaggtgaaag agcttacgat atctactcac gtttattgaa
     3781 agaccgtatc atcatgttaa gcggccaagt aacagatgat cttgctaatt cgatcatcgc
     3841 ccaattgctt ttcttagacg ctcaagattc tgaaaaagat atctatcttt atatcaattc
     3901 tcctggtggt tcagttacag caggtatggc tatttacgac acaatgaact ttgtcaaagc
     3961 agatgtccaa acaattgtta tgggtatggc tgcttcaatg ggaagcttct tgctgacagc
     4021 tggtacaaaa ggtaaacgat ttgctttacc aaatgctgag atcatgatcc atcaacctct
     4081 tggcggcgct caagggcaag caactgaaat cgaaattgcg gcacgccata ttttgcaaac
     4141 acgcgaacgc ttaaacaaaa ttttagctga acgcactgga caaccgcttg aagtgattga
     4201 aaaagataca gatcgtgaca actatatgac agctgaacaa gcaaaagcat atggattgat
     4261 cgatgaagtc atggaaaaca gttcttcatt aaattaatct gtttcaaagg aagctttttt
     4321 aagctctctt atctaaacca aataaaaaag gatggtcaac tcaaactgac catccttttt
     4381 tattttatgg atgctactgc ctatctttgc tccttgaatt ttccttgcgc atgcatccga
     4441 cctatctcga cataatgctg gatgttttct ttgttttttt gtatttcttc ttttgtcaaa
     4501 ggacggatca ctttagctgg gcgaccaaaa gccaagacat taggaggaat aacttttcct
     4561 tctgttacta atgatccagc accaatcaaa ctattctcac caataaccgc atgattcaat
     4621 atcgtggtcc ccatcccgat cagcgcccct ttttcgattg tacagccatg tagcatgcac
     4681 tgatgtccta ccgtcacatt ctccgcaata tctacaggtg catcatgatc gacatggatg
     4741 attgtaccat cttggatatt cgttctttgt cctattttta tccaattact gtccccgcgt
     4801 aaaacagctt gataccagat cgtcacatct tctgacaatg tcacatcacc aatcactgtg
     4861 gcatttgatg ctataaaccg ttccatattt atttttctcc tttcattttt tgtagaaact
     4921 aatcctattg aataaaggta tcatagcata tatttatttc ataagaaaaa aaacaggtaa
     4981 aacctgctca ggccagatgt ctatttacag tatctggtaa ctgacgtttt acctgttttt
     5041 attgtacatc tatattttct tctattactt tttttaaaat taattcgtac acttctattt
     5101 gtgctgccaa gcgttcgatt tgaaactcat tttcaaaaaa atcagctgaa tcaaaaggct
     5161 tcgtctgaca gacgtgcgtt aaacgatcaa cttctctttt ggcttcagta attttttcat
     5221 ttaaaaactg ttccatctcc gtgtcctcac ttttcttgat aactttactt taccattatc
     5281 aagaatagag aacaaaaaat aagttttaaa ctgttttatt cttatatgac ttattctgct
     5341 tcctcagcaa attggctgtt atacagtttt tcataaaatc caccttgtgc caataaactc
     5401 tcatgcgttc ctttttcaat gatctgacct tgatccatca ctagaatcag atctgcatca
     5461 cggattgtcg ataaacggtg agcgatgacg aaacttgtcc gtccctccat cacgcgatcc
     5521 attgcttttt gaatcaacgc ttctaaacgg gtgtctactg aacttgttgc ttcatctaaa
     5581 atcaagattt taggatcgga gaccactgct cgggcaatcg tcagcaactg tttttgtcct
     5641 aaagacacat tgtctccctc agaattgatg gccatatcat atccatctgg catcgttcgg
     5701 ataaaatgat ctacgtttgc tgttttcgca gcatcaacta cttcataatc tgtcgcatca
     5761 agctttccga agcggatatt atctgcaatc gttccttgat aaagccatgc atcttgcaag
     5821 accataccaa atagcgaacg cacatcactg cgactcattg atttggtgtc gattccatca
     5881 atccttattg ctcctttgtc tacgtcataa aaacgcatca atagattgat caatgtcgtc
     5941 ttgccggcac cggtcggacc gaccacagct acggtttgac cagctttcac ttcaaaattc
     6001 aaatcttgga ttaatggttt cttcggatca tatgcaaaat cgacatgatc gaatgtcaca
     6061 tctcctaaaa tcgtttctgg cagtgaagca tctactttgt tttctttttc ttctggctca
     6121 tctaaaatct cgaatacacg tttcgttgcc gctgatgcac tttgcaaaac tgaagacaat
     6181 tgtgtcacgt tccccattgg ctgactgatt tgccaaatat attggatgaa tgcttgtagt
     6241 tgaccgacaa cgatcgcccc agtaataaca taaaagcttc ctagaacagc cataccaata
     6301 taagtagcat aggcagttaa ttgaactaga ggcatcatca agccagaaat gaatgctgca
     6361 cgaaacccaa agtatttcaa gctgtgatta acttttttga atccttccaa tgtttctttt
     6421 tcgcgtccat atactttcaa tacactaaaa cctgtcatat tttcttggac gtagccgttt
     6481 agctcaccaa gagaattctg catgctttga aaatatttct gcgaagcatt gatcactcgt
     6541 tttgagatcc agatcgatgt tggaatcatg atcatagaga tcagcgccat catcggctgg
     6601 atataaaaca tcattgctgc agccaacgta attcccaata tcgcatttac gataccaata
     6661 aaagcttgtt gtaaagcacc gctgactgca tctacatcat tcgtcacacg agacaaaata
     6721 tttccttgct ggtttttatc gaaatatgaa accggaagac gattgatttt ttcttctatg
     6781 tctcttctca aatcatgcat ggcactttga acgacatttg tcatcaaaac accagaaagt
     6841 aattgcgaaa tacaataccc tattccaaca actgtgatcc aaatgagaca tttgaatata
     6901 taagaaaaat tgattgattc gccattggca atattacggc tgatttctgt agtaggaagt
     6961 cctgtaacat atggcaaagc cacgttgaaa gccactgtca gaactgtaaa taggatcact
     7021 aaaagaaaag tctcacgata cggtctgata tatcgagcta aacgttttaa ggaagaaaag
     7081 gtttttttca tgctaattcc tcctttgata attgagaagc ggcaatatca taataaatcg
     7141 ggcatttttc caacaactcc cgatgcgtcc ccataccgac gacttctcct tcatttaata
     7201 cgatgatctt atctgcatgc atgatcgttc ccacacgttg tgctacgatc aatacagtag
     7261 attctgtcgt ttcttttttc agacgagcac gtaacttcgc atccgtttga taatctaatg
     7321 cagaaaagct gtcatcaaaa atatagattt ccggacggcg tatgatggct ctggctattg
     7381 ccaatcgttg tttttgtcca cctgaaaaat tggaaccacc ttctgataaa tgttcattaa
     7441 atccatctgg ttttcgagaa atgaattctg aagcttgagc aatctcagct gcacgttcca
     7501 tttcttcttg cgtagcatct tctttcccgt atcgcaaatt atctgcaatc gttccagtaa
     7561 atagcagcgc tttttgcgga ataaacccaa tcttatctcg caacttgctt agccgataat
     7621 ctctcacgtc tactccatcg atcaagatct ttccttcact cacatcataa aagcgaggga
     7681 tcaattggat caacgtagat tttccgctac cggtacttcc aataaaagca acggtctctc
     7741 ctggagaggc tgtaaaactg acatttcgta tcactggctc ttgcgaatgg cctggataag
     7801 caaatgttac attttgaaat tcgatatacc ctttagtttt tgtatcagat ataccatttg
     7861 gatcttctac aatcgaaggt ttggcatcta gggcttcttg gatacgtcca gctgaaacag
     7921 ctgctcttgg atacatcatg aacacactag caaataacat gaatgagaac aaggcatgga
     7981 atatatactc gataaacgca atcaaatctc ctacacgaag ctcgcctgca tcgatttgca
     8041 ctgccccgct ccagatgatc aataccatta cgatattaaa taagaaataa aaacccggtt
     8101 gtgcaacagc catcaaacgg aataagcttt ttgaactaga agcataattc tcattgacta
     8161 cagcaaaacg tttttcttca aacttttcat tgacgaatgc acgaatcaca cgcaatcctg
     8221 aaagattttc ccgcaagata ctgttgattt tatctaagtt tttttgttgc tttttagata
     8281 acggttcaga caccttagca atcgctacga ctgccaataa tagtaaaggt aatgcaccta
     8341 ctacatacaa actgagtgtc acacttgtac gcatgaccat gtacaaactg acaatgaaca
     8401 tcattggtgc cataaaaccg atacgtaaaa tattttgcag gaacaacatg atctgataag
     8461 catcgtttgt tgtacgagtg atcaatgaag atacgcctag attttcgtat tcctgatgcg
     8521 aataactttg gatcttttcg aacaaatcat ctcgaatatc tgctacgata ttagtcgtaa
     8581 tcctcgaacc aaaataacct aacaagatat tcaaaataat accgattaca gtaataacga
     8641 tcataaatat cccttgttgc ttcacataat caaaatcatc attgcggatt cctacatcga
     8701 tcatacgtgc taaaatcgta ggaagtccta attcaatcaa aataaaacca aatacgcata
     8761 tgaaattgaa aaacaagaat ttcttataac gcatggtata atgccacatt agtttcactt
     8821 tctcatctcc ttttaatctt ttgttacatt ttcattacta aaaatgatag cacaacgagc
     8881 ctattaatag aacacttctc tcataaaaaa gtcattatga ttatagcggg atgataaaca
     8941 ttgatttttt ctttcaatct agttgatttc tatacttatt tgctgtttta tgctagaata
     9001 acaattaatt gttgtatatt ttttatacag aaggtacggt tgaaaaaata tccgaacaga
     9061 taagcaaaaa cgaggcttgt ctctttgact cgaatccagt attctagtca aagcatatga
     9121 aaaaccaggt ggcttgtccc ctcgttttgt gttgtctaaa aaaatcaact agctaaatca
     9181 ctgctttacg cagataaagg agacaaaaca atgatctata aagtttatta tcaagaaaca
     9241 aaagtacgca accctaaacg ggaagaaaca aaatctcttt acattgaggc aaaaagcgat
     9301 gtagacgctc gccaacgtgt ggaagaaaat accccataca atattgaatt cgttcaactt
     9361 ctagaaggaa gtcatctaga gtacgaaaaa gaaaatgctg atttctcatt agtggagttt
     9421 taatatgaaa ctttccatca aaaataacga gacaggcgtc tttgctattg gtggattagg
     9481 tgaaatcggg aaaaatacgt atggggtaca attccaagat gaaatcattt tgattgatgc
     9541 cgggatcaaa ttcccggaag acgatttact tggaattgac tatgtcattc ccgactacag
     9601 ctacatcata caaaacttac acaaagtaaa agccttggtg attactcacg ggcacgaaga
     9661 ccacatcggc ggaataccct acttgctgaa acaagcaaat attcctatct atgctggtcc
     9721 tctcgcatta gcgttgatca caaacaaatt agatgagcat ggcttgcttc gagatgcaga
     9781 gctccatgag atcaatgaag atacgatcat ccgttttaga aagacttctg tcagcttttt
     9841 cagaacgacc catagtatcc cagatgcatt agggatcgtg gtgaaaacac cttctggaaa
     9901 tatcgtagcg actggagact tcaaattcga tttcactcct gttggcgaac cagcaaactt
     9961 gcataaaatg gctcgtatcg gggaagaagg agtcttgtgc cttttatctg atagtacaaa
    10021 tgctgagatt ccaacattta ctaaatcaga aaaaacgatt gggcattcta ttttgaagat
    10081 cttttcaaaa atcgaaggac gtatcatttt tgccagcttt gcttctaaca tcttccgttt
    10141 gcagcaagca gcagatgccg ctgtggcaac tggtcgtaaa atcgctgttt tcggacgaag
    10201 catggaaaat gccatcgtca acggtcaacg tttaggatat atcaaagttc cagacggcac
    10261 atttgtagat gcacacgaaa tcaatcgctt gcctgccaat gaaacgatga tcctatgtac
    10321 aggttctcaa ggagaagcga tggccgcgtt gagccgcatc gcgaatggta ctcaccgtca
    10381 aatccaaatc cagccagacg atacagtgat cttttcaagt tcacctattc ctggtaatac
    10441 aacaagtgtc aatcatttga tcaatttgct gtctgaagct ggtgcagaag tgattcacgg
    10501 aaaaatcaat aacatccata cttccggtca cggtggacaa gaagaacaaa aattaatgct
    10561 tcgtttgatg aagccaaaat attttattcc tgtccacgga gaattccgca tgttgaaagt
    10621 acatgcttct ctagcacaag atgtaggtgt tcctgcagaa aactgcttca tcatggaaaa
    10681 tggcgatgtt ttagcgttaa ctagcgattc tgcgcgtcct gctgggcatt ttgtggctgg
    10741 agatgtgtat atcgatggta gcgggatcgg tgatattggt aatgtcgttt tacgtgaccg
    10801 tcacctgctt tcagaagaag gtcttgtatt agctgtcgcg acagtggata tcaagaaaaa
    10861 agaaatcttg gctggtccag atattctctc tcgtggattt gtctacatgc gagaatcagg
    10921 agaaatgatc aatgaagctc agcgaatctt attccacgct ttaagagaat gtttgaatgg
    10981 acctgactgt tcagaatata aattgaaaga agcgatgact ggcgcgcttc agcctttctt
    11041 attcgaacgt acagaaagac atccaatgat tttgccaatg gtaatgacac cagatgaaga
    11101 ataaataaga ggttatgaaa tcagcacctt gtcctgaata taagagaaaa caaatgaaaa
    11161 acatgagaag ccatttttgt ttgttcttat tccttgatac aaggtggctc tttcatagcc
    11221 tcttaaattt atttactttt tcatacaaaa aaata
//
LOCUS       DAFBVQ010000078        10730 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.081, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000078 DAFBVQ010000000
VERSION     DAFBVQ010000078.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10730)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10730)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10730
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.081"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..440
                     /locus_tag="LLC22_002423"
     CDS             <1..440
                     /locus_tag="LLC22_002423"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="topoisomerase C-terminal repeat-containing
                     protein"
                     /protein_id="HBK5435671.1"
                     /translation="TFLANIQKFVSHLLEVVPGQIQSTDFGSTLQEVKAASEKQEATR
                     HLGVCPKCREQEVLLYQNVAACTSEACDFKLWTTIAKKKLTATQLKEIIQNGRTSQSV
                     RGLKGQKGSFEATIVLKEDFTTGFEFSEKKKTNYKKRTRRTTK"
     gene            456..605
                     /locus_tag="LLC22_002424"
     CDS             456..605
                     /locus_tag="LLC22_002424"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435672.1"
                     /translation="MRNTTHKQQEIENQKAKIRLEQEKLRANKRRLQQLKNQQRIQKE
                     IELDR"
     gene            681..1274
                     /locus_tag="LLC22_002425"
     CDS             681..1274
                     /locus_tag="LLC22_002425"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737159.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBK5435673.1"
                     /translation="MQDKLKELLAIRDGNLSMKEARKFGIAATTVQRLVNQGKLIKVD
                     RGYYVEDGHGIDDLFWLQQRFSRGIFSHETTLDIYQLSTNMPKFIHLTFPHGYNVDRS
                     ITKEQQLQFHFVKKEVYELGKVEGTSFQGNPITMYDKERTLCDIWNPRYEFEYEMKLE
                     ALKEYMEDPLRDPSKLRDYMTKLHVEKEMKYHMQSLY"
     gene            1287..2186
                     /locus_tag="LLC22_002426"
     CDS             1287..2186
                     /locus_tag="LLC22_002426"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303312.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBK5435674.1"
                     /translation="MTPTQFAAKTRNLAKSTGLNAQLVQRHFMMDRLIEQISESKYKN
                     DFILKGGFLLGSKYGIDRRTTIDIDTTFRNSKLTEEKLKSIFNDLTRKPTKEGIVFSI
                     QGMKETREADFYPGFQIKLVANLEKVRVPFKMDVTTGDSIYPEVDTHYHQLMFEDKKV
                     EIPAYPTEQIIAEKLSATFSFGTDNSRAKDYYDLFTIPKLENIDTKELYKSVRNTFTK
                     RGDTKPLSFYYEREMDKIRGNDYLEKQWEKYRSVNTFANSISFTDTVNEIDHLMKSVI
                     KIENQERKRQFKRSQQMNQEMER"
     gene            2189..2662
                     /gene="ssb"
                     /locus_tag="LLC22_002427"
     CDS             2189..2662
                     /gene="ssb"
                     /locus_tag="LLC22_002427"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000609607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5435675.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFANQNGNR
                     EADFINCVIWRKPAETMATLAKKGGLIGVVGRIQTRTYDNQQGQRVYVTEVVADNFQL
                     LESKAATESRAHADQSTTSPSPTTFEQRDTNNGLDASQNPFGGQSIDISDDDLPF"
     gene            3028..3288
                     /locus_tag="LLC22_002428"
     CDS             3028..3288
                     /locus_tag="LLC22_002428"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339774.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435676.1"
                     /translation="MNKYVGLLDKIRVIKTQPLLVRFTLQTIHESINCVVADIEIIDK
                     LLIMDDGKYNIAVTGHFNKRNQLVIASMYVRNPDQFTRLMGI"
     gene            3733..3939
                     /locus_tag="LLC22_002429"
     CDS             3733..3939
                     /locus_tag="LLC22_002429"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBK5435677.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYRLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            3939..4190
                     /locus_tag="LLC22_002430"
     CDS             3939..4190
                     /locus_tag="LLC22_002430"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435678.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEALLIPRYWTTETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTELEN"
     gene            4206..4622
                     /locus_tag="LLC22_002431"
     CDS             4206..4622
                     /locus_tag="LLC22_002431"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922517.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435679.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKERLSV
                     AVEEMIESGVEMNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQALE
                     LTYAKFIETKKAKTVSSEWLDYFENINKYGACYIMK"
     gene            4604..4876
                     /locus_tag="LLC22_002432"
     CDS             4604..4876
                     /locus_tag="LLC22_002432"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435680.1"
                     /translation="MLHHEVIRRIQKDFSCMEEMKYFVQNVEEQLYLESETSQTKVTV
                     SHNRLDVYKRRPESLKKGAELLRLETEKYVMNVYLEKSELVENFMD"
     gene            5043..5444
                     /gene="tnpA"
                     /locus_tag="LLC22_002433"
     CDS             5043..5444
                     /gene="tnpA"
                     /locus_tag="LLC22_002433"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_045009167.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBK5435681.1"
                     /translation="MSEIHYGRGYVYSIQYHLVWCVKYRHDVLYGQVDIDVKQFLKQI
                     ADDNNIKIIEIESDKDHIHLLIECTPQHYIPSIVKVFKGASARLLFKKHPELKQLLWG
                     GHLWNPSYFVATVSENTEEQIRKYIQNQKKK"
     gene            5456..6601
                     /locus_tag="LLC22_002434"
     CDS             5456..6601
                     /locus_tag="LLC22_002434"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305757.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5435682.1"
                     /translation="MLQHRAYKFRIYPNQEQEILMTKTIGCSRFVYNYFLNLWNHEYT
                     TTGKGLSYNSCSAMLPQMKRNAETIWLKEVDSIAIQSSLKNLSDAFSRFFKKQNKRPQ
                     FKSKKHPIQSYTTKNVNNSIEIRNNFVKLPKLGFVKFAKSQEPKGRILNATIRKNSSG
                     KFFVSILCEEEIVEFPKSNSAIGIDLGITDFAILSDGQKIDNNKFTSKMAKKLKREQR
                     KLSKRALLAKKKGVNLFEAKNYQKQKRKVARLHEKVMNQRNDFLNKLSTEIIKNHDII
                     CIEDLNTKGMLRNHKLAKSISDVSWSSFVTKLQYKANWYGRKIIKVDKWFPSSQICSN
                     CGHKDGKKSLEIREWTCPVCHAHHDRDINASINILTEGLRLHVMGLA"
     gene            6839..7102
                     /locus_tag="LLC22_002435"
     CDS             6839..7102
                     /locus_tag="LLC22_002435"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PbsX family transcriptional regulator"
                     /protein_id="HBK5435683.1"
                     /translation="MEMLPIKKWGNSNGLRLPKYIMEYLGIHTEDKVKIIQEEVNGQK
                     RLIIEAANIENELTIEQLFENYTDERNHVTIQNLGEAVGNEKW"
     gene            7096..7446
                     /locus_tag="LLC22_002436"
     CDS             7096..7446
                     /locus_tag="LLC22_002436"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016610020.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system PemK/MazF family
                     toxin"
                     /protein_id="HBK5435684.1"
                     /translation="MVRKPRQGDILLLNTAPRSGHEQTGKRPYIVLSHDIIADYSNVV
                     TVAPISSTTRNYPLYVNINSEYEMKTTGKVLLDQLTTIDYEARECIFLEKAHDSLVEE
                     LLMKVRTVFQKVSK"
     gene            complement(7470..8084)
                     /locus_tag="LLC22_002437"
     CDS             complement(7470..8084)
                     /locus_tag="LLC22_002437"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5435685.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDFVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVQLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSANAKDPQ
                     RRLVYKNIVEDLKKGVAIAKIAKDYNVTRQTVYRIKKDSMVNHE"
     gene            8398..8820
                     /locus_tag="LLC22_002438"
     CDS             8398..8820
                     /locus_tag="LLC22_002438"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303116.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435686.1"
                     /translation="MKNKFILSLGILTIGISVTGTTIPTFADSTNEPTTVVDNNQELT
                     PLDRNGIAIGNPTNDLTVTENYLIVSPLLARAASKTIRVTGTMIFDKVGWPSRPPQSR
                     NWKEKRNGYWYYGKLYLQSYKSAGNNWIATYSGTLTRK"
     gene            8830..9033
                     /locus_tag="LLC22_002439"
     CDS             8830..9033
                     /locus_tag="LLC22_002439"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631607.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435687.1"
                     /translation="MPEFVNTPNFYQDSDILSKINLPKEESALQVQRTLQETQKIQKS
                     ISNLEDSEEKRKKRDQKTYQKEK"
     gene            9244..9828
                     /locus_tag="LLC22_002440"
     CDS             9244..9828
                     /locus_tag="LLC22_002440"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_007207927.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5435688.1"
                     /translation="MKIGYARVSTGLQNLDLQEDSLNKFGCEKIFTDHMSGAKSNRPG
                     LEMAIDFVRSGDTLVVWRLDRLGRNMEDLISIVNRLNERGVSFHSIQENITMDKSSST
                     GQLMFHLFAAFAEFERNLILERSAAGRAAARARGRFGGRPEKLSEQDLELLKTLVDSG
                     TPIKTIAERWNVSRTTIYRYLAKMEEKNGKTNSH"
     gene            9997..>10730
                     /locus_tag="LLC22_002441"
     CDS             9997..>10730
                     /locus_tag="LLC22_002441"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HBK5435689.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRS
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTKSLNLFTTEETRSQRRKKLAQMIQERIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFIAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGILSIRDLANWNPYTIKNRLGVIG"
BASE COUNT         3901 a         1687 c         2042 g         3100 t
ORIGIN      
        1 ctactttctt agctaatatc caaaaatttg tctctcactt gttggaagtc gtaccgggac
       61 aaatccagtc aacagatttt ggatcaacgt tacaagaggt gaaagcagcc agtgaaaaac
      121 aggaagcaac gcgtcattta ggtgtttgtc caaaatgtcg ggaacaagaa gtcttgcttt
      181 atcaaaatgt ggcggcatgt acgtctgaag cctgtgattt taaattatgg acaacgattg
      241 ccaaaaagaa actcacagcc acacaactga aagagatcat tcaaaacggc cgaacaagcc
      301 aatcagtcag aggactaaaa ggtcagaaag gttcgtttga agcaacgatc gttttaaaag
      361 aagactttac aacaggcttt gaattttctg aaaagaaaaa aacgaactat aagaaaagaa
      421 cacgccgcac tacaaaataa tgaaggggtt atcctatgcg aaatacaaca cacaaacaac
      481 aagaaatcga aaatcaaaaa gcaaaaattc gtttagaaca agagaaatta cgtgcaaata
      541 aaagaagact gcaacaatta aagaaccagc agcgcattca aaaagaaatc gaattagatc
      601 gatagacgtt aatcttgtta caaataaact actatgatat atttgatgta gtgtatttgt
      661 aacgaaggga ggggaagtaa atgcaagata aactgaaaga attgttggct attcgcgatg
      721 gaaatttatc tatgaaggaa gccaggaaat ttggaatcgc agcaaccact gtacaaagat
      781 tggtgaatca aggaaaattg atcaaagttg atcgtggtta ttatgtagag gatggtcatg
      841 gaatagatga tttattttgg cttcagcaac gattttccag gggaatcttc tctcatgaaa
      901 cgactttaga tatttaccag ctttctacga atatgccgaa attcattcac ttaacttttc
      961 cccatggcta taacgttgat cgttcaatta caaaagagca gcagttacaa tttcatttcg
     1021 tgaagaaaga agtttatgaa ctaggaaaag tagagggaac ttcctttcaa ggaaatccta
     1081 ttactatgta tgataaagag cgtacacttt gtgatatttg gaatccgaga tatgaatttg
     1141 aatatgaaat gaaattagaa gcattaaaag agtacatgga agacccattg agagatccaa
     1201 gtaaattaag agattacatg acaaaactac atgtagaaaa agaaatgaaa taccacatgc
     1261 aaagcttata ttgatggagg aaaaagatga caccgacaca atttgcagca aaaacaagaa
     1321 atttagcaaa gagtacagga ttaaatgcac agttagtgca acggcatttt atgatggatc
     1381 gtctaattga acaaatttct gaatcaaagt acaaaaatga cttcattttg aaaggcggct
     1441 ttttattagg atcaaaatat ggaatcgata gaaggacaac aattgatatc gatacgacat
     1501 ttagaaatag caaattaact gaagaaaaat tgaagagcat ttttaatgat ttaactagaa
     1561 aacccacaaa agaaggcatt gttttctcta ttcaaggaat gaaggaaaca agagaagccg
     1621 atttttatcc tggatttcaa attaaattgg tggctaattt agagaaagta cgtgtaccgt
     1681 ttaaaatgga cgtgacaaca ggagattcta tttatcctga agtagataca cactatcacc
     1741 aattaatgtt tgaagataaa aaagtggaga ttccagctta tccaacagaa caaattattg
     1801 cagaaaagct aagtgctacg ttcagctttg gcacagataa ttcgagagca aaagattact
     1861 acgacttatt taccattccg aaactagaaa atatcgatac gaaagagtta tacaaaagtg
     1921 ttcgaaatac atttacaaaa cgtggggata caaaaccgtt gtccttttat tatgaaagag
     1981 aaatggataa gatcagagga aatgactatt tggaaaagca gtgggaaaaa tatcgctcag
     2041 ttaacacgtt tgcgaattcc atttcattta cagatacagt caacgaaatt gatcacctaa
     2101 tgaaaagtgt gatcaaaatt gaaaatcaag aaagaaaacg gcagtttaaa agatcacaac
     2161 aaatgaatca agaaatggag agataaagat gattaataat gtgacattag taggacgctt
     2221 aaccaaagat cccgatttac gttatactgc aagtggcaca gcagtagcga cttttaccct
     2281 agccgtcaac cgaaatttcg cgaatcaaaa cggcaatcga gaagccgatt ttattaactg
     2341 cgtgatttgg cgcaaaccag cagaaacaat ggcgacatta gctaaaaaag gcggcttgat
     2401 cggtgttgtc ggacggattc aaacacgaac ttatgacaac cagcaaggac aacgtgtgta
     2461 tgtgactgaa gttgtagcag ataactttca actattagaa agtaaagcag cgacagagag
     2521 ccgtgcgcac gctgatcaat caaccaccag tccaagcccc actacctttg aacaacggga
     2581 tacaaacaat ggattggacg cttcacaaaa tccatttggt ggacaatcaa tcgatattag
     2641 cgatgatgat ctaccattct aagtagcatt ttctattggt tgcatttgct acggtttatg
     2701 ttataattta gtcaacaaaa agaattttca atctataacc aaaaaccact agctggcggg
     2761 ctagtggttt tcttttacgt ttctattata agaattaacg ggtaggctta ctgtctttct
     2821 tggcaaattt acaatcaagc catttgcaga tatagtgcgc ggctacttct gccatgattg
     2881 caaaaacaaa atcaaaaaga attttcaaac ctataacctc ctccccttgc cagattaggc
     2941 cggggtagca gacagcaaga ctattatagc ataattgaaa tattcaaatg attggatttt
     3001 tgctataatt ttagcgaggt gattgtgatg aacaaatatg ttggtttgct tgataaaatc
     3061 cgagtaataa aaacgcaacc gttattggtt cgctttactt tacaaacgat tcatgaatcg
     3121 attaattgtg tagttgcaga tattgaaatt atcgataaat tgctaattat ggatgatgga
     3181 aaatacaata ttgccgtcac aggtcacttc aataaacgaa accagctagt tattgctagc
     3241 atgtatgtta gaaatcccga tcagtttacg cgattgatgg gcatataaaa aaagaagagt
     3301 tgcaatccta atgtaggact gcagctcttt ttgttttaca tagaaacaag aaaaatgaaa
     3361 aggccttttt aggaaggcgc gagcgccttc tcaattgaaa aacctctctc actccaaccg
     3421 ccaccgccgt tcgagaagaa aggaagtgaa cgttgcacgt tcactaagat aaagggtctt
     3481 gcaaagcaag acaaaataga aaaaacttcc tctcaccaaa aggttcgttc ctgttcgtta
     3541 tctctttatt gatttgccag accggcaaca agttgccttt tatcaccaaa aagcgacaag
     3601 gacaagggta aatggcacgc tgcgcgccct tgtccttgtc gcttttcgtt gattcattct
     3661 ggccaacaaa tcaataaaga aagaactaac gaaaggaagt aaaacctttc ctaagaggag
     3721 gcagaatcaa tcatgcgaaa gaaatttgat tattggggtg ttcccttcag cgaattattc
     3781 ccaaactatc atgcaccaca tactgtcgaa tgcgattgtg gagaaagagc gaaatgtatc
     3841 aaaagctatc gtttgtatca atgtccaaca tgcgggaaaa aatatacctt gtcttatggc
     3901 gattatattt tgattgatga gaaaggaaag aaacgttgat gaaaacacaa cacaaattat
     3961 tgactgtaaa agaagtcgtt caaattttgg tggacaaaga agtcatttct gaaaaagtag
     4021 cagaagcttt acttattccg cggtactgga cgacagaaac ccctttagta gaggatgcac
     4081 cgactatgct atttgaagac ctagtgaaga ttgcaggata tgaactgcat tatcaagaaa
     4141 acttggaaac ttatgaaaac gaatattggt taaccgaatt agagaactaa aaaggagaaa
     4201 aaaatatggc tcaaaattac tatgacgaat ttgtcaaatt acctttggat aaaatggcac
     4261 aaaaaatgga ggatatgaca ttcctataca atgagacacg tgttccaaaa aaacattata
     4321 aggaaagatt gtcggtagct gtggaagaaa tgattgaatc aggtgtcgaa atgaatctca
     4381 ttgcgacgta ttatcgaaca ctggaagaac tgaaaaagca aaatgcaaaa tggtttttcc
     4441 aagccttact atgcttggaa gtaggcgtca aaccaagcac aatcaaacct tctgaatacc
     4501 aagctttaga actaacgtat gcgaaattta tcgaaacgaa aaaagctaag actgtttcaa
     4561 gtgaatggtt agattatttt gaaaatatca ataagtatgg cgcatgttac atcatgaagt
     4621 aatcagacgg attcaaaaag actttagttg tatggaagaa atgaagtact ttgttcaaaa
     4681 tgttgaagaa cagttatatt tggaaagcga aacgagtcaa acaaaggtca cagtcagcca
     4741 taatcgttta gatgtgtata aacgtcgtcc tgaatcatta aaaaaaggag cggagcttct
     4801 acgactagaa acagaaaaat acgtcatgaa tgtttaccta gaaaaaagtg agttggtcga
     4861 aaattttatg gactagccga gaacacccgt gattttaatc atgggatgaa tcggattcag
     4921 ttgtgaccta gctttagcta ggttaaacaa ctgacaaata taaactaaat aatagtgaaa
     4981 tgtcttgcaa taattgattt tgtagaaata catatattaa aataattgcg aggtgttttt
     5041 gtatgtcaga aattcattat ggacggggtt atgtctattc tattcaatat catcttgttt
     5101 ggtgtgtaaa atatcgacat gatgttttgt atggtcaggt agatattgat gtcaaacagt
     5161 ttttgaaaca aattgctgat gataataata taaaaattat agaaatagaa tcagataaag
     5221 accatattca tttactcatt gaatgcaccc cacaacacta tattcctagt attgttaaag
     5281 tatttaaagg cgcatccgct agactgctgt ttaaaaaaca tcctgaactt aaacaactcc
     5341 tttggggtgg acatctttgg aatccaagct actttgtagc tactgttagc gaaaatacag
     5401 aagaacaaat tagaaaatat atacaaaatc agaaaaagaa atgaggtgaa tccgtatgct
     5461 acaacatagg gcttataaat ttagaatcta tcctaatcaa gaacaagaaa tattaatgac
     5521 taaaactatt ggctgttcaa gatttgtcta taattatttt ttgaatttgt ggaatcatga
     5581 atatacgact actggaaaag gattatctta taattcttgt tctgccatgc ttccacaaat
     5641 gaaaagaaat gcagagacaa tttggttaaa agaagttgac agtattgcga ttcaatcctc
     5701 attgaaaaat ctttctgatg ctttttctcg cttctttaaa aagcaaaata aacgaccaca
     5761 atttaaaagt aaaaaacatc ctatacaaag ttatacaact aaaaatgtga ataatagtat
     5821 cgaaattaga aacaatttcg taaaactacc taagttagga tttgttaaat ttgcgaaaag
     5881 tcaagagccc aaagggcgaa tcttaaatgc tacgattcga aaaaattcga gtggtaaatt
     5941 ttttgtttcc atcctgtgtg aagaagaaat agttgagttt cctaaatcta attccgctat
     6001 tggaatcgac cttggtataa ctgattttgc aatcctttct gatggtcaaa agattgataa
     6061 caataaattc acgtcaaaaa tggcaaaaaa actcaaacgt gaacaacgta agttgtcaaa
     6121 acgtgcatta ctagctaaaa agaaaggcgt caatctcttt gaagctaaaa attatcaaaa
     6181 acaaaaacga aaagtagcac gactacatga aaaagtaatg aatcaacgca atgacttttt
     6241 aaacaagttg agcacagaga ttatcaaaaa ccacgatatt atctgtatag aagacttaaa
     6301 tacaaaaggt atgttgcgta atcataaact agcaaaaagc atttctgatg tgtcttggtc
     6361 tagttttgtg actaagttac aatacaaagc taactggtac ggtcggaaaa tcatcaaagt
     6421 agataaatgg tttccatcta gtcaaatctg ttcaaattgt ggacacaaag acggcaagaa
     6481 atctctagaa attcgagaat ggacttgtcc tgtttgtcat gctcatcatg accgagatat
     6541 caatgctagt atcaatattt tgaccgaagg tctaagatta catgtcatgg gattagctta
     6601 gatccaatca tcaaaaaccg taggaactac ggggatagct tggtaaataa gagaaaccgc
     6661 tgtgagtaaa gaaatacgct tgcaagtatg ctctattccc aagaatctcg tgactttagt
     6721 catgagaggt tcaaggattc atggaatgtt aatctaattt aatagaaaag gataattaag
     6781 tatatacgtt ttttcttatg tatgttatac tatgtatata cagaaagagg tgtctactat
     6841 ggaaatgtta cctataaaaa aatggggaaa tagtaatggc cttagattgc caaagtatat
     6901 tatggaatat cttggaattc atacagaaga caaagtgaag ataatacaag aagaagtaaa
     6961 cggtcagaag cggctaatta tcgaagcggc taatatagaa aatgaattaa caattgaaca
     7021 gttatttgaa aattacactg atgaaagaaa tcatgtgacg attcaaaatt taggtgaagc
     7081 agtaggtaat gaaaaatggt gagaaaacct agacaaggcg atattctatt attgaataca
     7141 gcacctcgat ctggacacga acagacaggt aaaagacctt atattgtttt aagtcatgat
     7201 attattgcgg attatagtaa cgttgttaca gttgctccaa tttctagtac aactagaaac
     7261 tatccgctat atgtaaatat aaactcagaa tatgaaatga agacaacagg aaaagtatta
     7321 ttagatcaac taacgacaat tgattatgaa gccagagagt gtattttttt ggaaaaagcg
     7381 catgatagtt tagttgagga gttattgatg aaagttagaa cagtttttca aaaagtaagc
     7441 aaataaaata gaaacagcag catgatcaac tattcgtgat tgaccatgct gtcttttttt
     7501 attctatata cggtttgtct cgtaacattg tagtcttttg caatcttagc gatcgcaaca
     7561 ccttttttta gatcctcaac gatgttttta taaacaagac gacgttgggg atcttttgca
     7621 ttggcactgt atagcttagg acgtccttta taaacaccgt tcgcttttgc aatcttaatg
     7681 ccttgtgcct gacgtcgttt agattcggta cgttcttgtt cagcgatcat ggccaaaatt
     7741 tgaatgatca aatctttaat gaatttatcc aggagaggat tgccaattgc ttcggccatg
     7801 atcggtagac ttgtgatgat cagctgcaca tttttcttct tcaagtaatt gactgaagcg
     7861 atgatctcgt cgtaatttct tccaagtcga tcaatagctt ccacaataaa aatatcttga
     7921 tctcggacga aatccagtgc ttcttgaaaa acaggtcgat gagtaatcgt tgcgccagat
     7981 tgtttctcaa tgaaaattct ctctgcaccg aattttttca tttcttcaat ctgccgttgt
     8041 tcattttgat cgatggatga gacacgtatg tatgcaactc tcaaaatttt tacctacttt
     8101 ctgcaactat ttaaaaaaca ccctaatcat acacgagaaa accagatttt tcaatgtcgc
     8161 ggtcgtgtct agttagggta taccttatat agacaaaaac taatgatgga ggaaatagta
     8221 tgtgtcactt ttctttttaa atggcaatat tttttgtaaa taaatgtcaa tcaagaaaat
     8281 ttaaacgatt atgacattaa aaatatattt tatgaatttt ctagtatata acttgattta
     8341 tctgttaaga tttattaaga aaacgttttc ttatttttga tttcgaggtg atagacaatg
     8401 aaaaataagt ttattttatc tttaggtatt ttaactattg gaattagtgt aactggaact
     8461 acaattccta catttgctga tagtacaaat gaaccaacta ctgtagtaga taataaccaa
     8521 gaattaactc ctttagatag gaacggaata gccattggta acccaactaa cgacttaact
     8581 gttactgaaa attatttaat agtttctcca ttacttgctc gagcagcttc taaaacgata
     8641 cgagtgacag gaacgatgat ttttgataaa gttggttggc cttctagacc tcctcaatca
     8701 cggaattgga aagaaaaaag aaatggttat tggtactatg gaaaattgta tttacaaagt
     8761 tataaatcag ctggaaacaa ttggattgcg acttattcag gaaccttaac tagaaagtag
     8821 ggatttttta tgccagaatt tgtgaacaca ccaaattttt atcaagatag cgatattcta
     8881 agtaaaatta atttaccgaa agaagaatca gctttacaag ttcagcgaac tttacaggag
     8941 acacaaaaaa ttcaaaaatc aatttctaat ctagaagatt ctgaagaaaa aagaaaaaaa
     9001 agagaccaaa aaacatatca aaaagaaaaa taatgatttt aaaaaaagag tgtctagtcg
     9061 acattctttt tttctaattg aaagtgttca taaaatcacc catttctgga cactttcttt
     9121 ttttgcttta tttttcaaaa aaacaattca tttcatgttc ataaacccat aacaatatct
     9181 atgttcagtt aaactatatg gataaagtta tgttacaata aaattaatga aggagtgatt
     9241 tttttgaaaa taggatacgc ccgggtatct actggtttac aaaatttgga tttacaagaa
     9301 gacagcctaa ataaatttgg ttgtgaaaaa atttttactg atcatatgag tggggcaaaa
     9361 agtaatcgac caggattaga aatggccatt gattttgttc gctctggcga tacacttgtc
     9421 gtttggcgct tagatcgttt aggtagaaat atggaagatt tgatttcaat cgtcaatcga
     9481 ctgaatgagc gtggtgtgag ttttcatagt attcaagaaa atattacgat ggacaaatca
     9541 agttctacag gacagctcat gtttcatttg tttgcggcat ttgcagaatt tgagcgtaat
     9601 ttgatcctgg aacgatccgc agcaggacga gcagctgctc gtgcaagagg acggtttggt
     9661 ggtcgtcctg aaaaattgtc tgaacaagat ttggaattac tgaagacttt agtggatagc
     9721 ggtacaccta ttaagactat tgcggaacgg tggaacgtct caagaaccac catttatcgt
     9781 tatttggcaa aaatggagga gaaaaatgga aagacaaatt ctcattagtt tttgtcattt
     9841 aatgctgaaa atttttgcca tttatctaga aaagtgacaa tagtatgaga attttttgta
     9901 agtgtctact gataacttat tctcaaatat ttagctattt cttctttaca acatcgaaca
     9961 tatgtttgta taatgtggaa gaatggagtg ttatttatga tggattattc aaaagagcca
    10021 gtaaatgatt actttttaat cgatatgaaa agcttttacg caagtgtcga atgtatagaa
    10081 agaaatttag atccattaac aacagaactt gttgttatga gtcgatctga taatactggt
    10141 tcaggattga tattagcttc ttctcctgaa gcaaaaaagc ggtatggtat tacaaatgtg
    10201 agtagaccac gtgacttacc acaaccattt cctaaaacac tacacgttgt tccaccacgt
    10261 atgaacctat atatcaagcg aaatatgcag gtaaataata ttttcagaag atatgtggct
    10321 gatgaagatc tactgattta ctcgatcgat gaatcgattt taaaagtgac aaaatcactg
    10381 aatcttttta cgactgaaga aacacgaagt cagcgaagga agaagctcgc tcaaatgatc
    10441 caagaacgta ttaaagaaga gttaggtttg attgctacgg taggcgtcgg cgataatccc
    10501 cttttggcta aattagcctt agacaatgaa gcaaagcata atgaaggatt tattgcggaa
    10561 tggacgtacg aaaacgttcc tgagaaagta tggaatattc ccgaaatgac ggacttttgg
    10621 ggaattggtt cgcgaatgaa aaaaaggctc aaccaaatgg gaattttgag cattagagac
    10681 cttgctaact ggaatcctta tacgattaag aatagattag gtgtgattgg
//
LOCUS       DAFBVQ010000079        10575 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.082, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000079 DAFBVQ010000000
VERSION     DAFBVQ010000079.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10575)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10575)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10575
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.082"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            12..84
                     /locus_tag="LLC22_002442"
     tRNA            12..84
                     /locus_tag="LLC22_002442"
                     /product="tRNA-Val"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:45..47,aa:Val,seq:tac)
     gene            88..160
                     /locus_tag="LLC22_002443"
     tRNA            88..160
                     /locus_tag="LLC22_002443"
                     /product="tRNA-Lys"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:121..123,aa:Lys,seq:ttt)
     gene            168..249
                     /locus_tag="LLC22_002444"
     tRNA            168..249
                     /locus_tag="LLC22_002444"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:202..204,aa:Leu,seq:tag)
     gene            267..339
                     /locus_tag="LLC22_002445"
     tRNA            267..339
                     /locus_tag="LLC22_002445"
                     /product="tRNA-Thr"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:300..302,aa:Thr,seq:tgt)
     gene            351..422
                     /locus_tag="LLC22_002446"
     tRNA            351..422
                     /locus_tag="LLC22_002446"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:383..385,aa:Gly,seq:gcc)
     gene            439..524
                     /locus_tag="LLC22_002447"
     tRNA            439..524
                     /locus_tag="LLC22_002447"
                     /product="tRNA-Leu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:473..475,aa:Leu,seq:taa)
     gene            535..608
                     /locus_tag="LLC22_002448"
     tRNA            535..608
                     /locus_tag="LLC22_002448"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:569..571,aa:Arg,seq:acg)
     gene            618..691
                     /locus_tag="LLC22_002449"
     tRNA            618..691
                     /locus_tag="LLC22_002449"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:652..654,aa:Pro,seq:tgg)
     gene            711..783
                     /locus_tag="LLC22_002450"
     tRNA            711..783
                     /locus_tag="LLC22_002450"
                     /product="tRNA-Ala"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:744..746,aa:Ala,seq:tgc)
     gene            811..884
                     /locus_tag="LLC22_002451"
     tRNA            811..884
                     /locus_tag="LLC22_002451"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:845..847,aa:Met,seq:cat)
     gene            898..971
                     /locus_tag="LLC22_002452"
     tRNA            898..971
                     /locus_tag="LLC22_002452"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:932..934,aa:Ile,seq:cat)
     gene            995..1084
                     /locus_tag="LLC22_002453"
     tRNA            995..1084
                     /locus_tag="LLC22_002453"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1031..1033,aa:Ser,seq:tga)
     gene            1097..1170
                     /locus_tag="LLC22_002454"
     tRNA            1097..1170
                     /locus_tag="LLC22_002454"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1131..1133,aa:Met,seq:cat)
     gene            1189..1264
                     /locus_tag="LLC22_002455"
     tRNA            1189..1264
                     /locus_tag="LLC22_002455"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1222..1224,aa:Asp,seq:gtc)
     gene            1266..1336
                     /locus_tag="LLC22_002456"
     tRNA            1266..1336
                     /locus_tag="LLC22_002456"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1298..1300,aa:Gly,seq:tcc)
     gene            1350..1423
                     /locus_tag="LLC22_002457"
     tRNA            1350..1423
                     /locus_tag="LLC22_002457"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1384..1386,aa:Ile,seq:gat)
     gene            1448..1535
                     /locus_tag="LLC22_002458"
     tRNA            1448..1535
                     /locus_tag="LLC22_002458"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1482..1484,aa:Ser,seq:gct)
     gene            1557..1628
                     /locus_tag="LLC22_002459"
     tRNA            1557..1628
                     /locus_tag="LLC22_002459"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1590..1592,aa:Glu,seq:ttc)
     gene            1651..1740
                     /locus_tag="LLC22_002460"
     tRNA            1651..1740
                     /locus_tag="LLC22_002460"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1687..1689,aa:Ser,seq:tga)
     gene            1753..1826
                     /locus_tag="LLC22_002461"
     tRNA            1753..1826
                     /locus_tag="LLC22_002461"
                     /product="tRNA-Met"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1787..1789,aa:Met,seq:cat)
     gene            1845..1917
                     /locus_tag="LLC22_002462"
     tRNA            1845..1917
                     /locus_tag="LLC22_002462"
                     /product="tRNA-Asp"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1878..1880,aa:Asp,seq:gtc)
     gene            1921..1993
                     /locus_tag="LLC22_002463"
     tRNA            1921..1993
                     /locus_tag="LLC22_002463"
                     /product="tRNA-Phe"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1954..1956,aa:Phe,seq:gaa)
     gene            1998..2068
                     /locus_tag="LLC22_002464"
     tRNA            1998..2068
                     /locus_tag="LLC22_002464"
                     /product="tRNA-Gly"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2030..2032,aa:Gly,seq:tcc)
     gene            2081..2154
                     /locus_tag="LLC22_002465"
     tRNA            2081..2154
                     /locus_tag="LLC22_002465"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2115..2117,aa:Ile,seq:gat)
     gene            2166..2237
                     /locus_tag="LLC22_002466"
     tRNA            2166..2237
                     /locus_tag="LLC22_002466"
                     /product="tRNA-Glu"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:2199..2201,aa:Glu,seq:ttc)
     regulatory      2426..2505
                     /regulatory_class="riboswitch"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF01767"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="SAM riboswitches modulate the expression of
                     downstream genes in response to levels of
                     S-adenosylmethionine. SMK box riboswitch (aka SAM-III)
                     shares no known similarity to SAM-I and SAM-II; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /bound_moiety="S-adenosylmethionine"
                     /db_xref="RFAM:RF01767"
     gene            2503..3696
                     /locus_tag="LLC22_002467"
     CDS             2503..3696
                     /locus_tag="LLC22_002467"
                     /EC_number="2.5.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318393.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="methionine adenosyltransferase"
                     /protein_id="HBK5435690.1"
                     /translation="MVERHLFTSESVSEGHPDKIADQISDAILDAILKQDPTARVACE
                     TSVTTGLVLVFGEISTTAYVDIQKVVRETIKEIGYTRAKFGFDGDTAAVLVAIDEQSP
                     DIAQGVDEALEIRDEDKKDVLDEIGAGDQGLMFGFAVDETPELMPLPIALSHRLVRRL
                     ADLRKSNELTYLRPDAKSQVTVEYDDQGQPERVDTIVISTQHDDAVDNETIRHDVIEK
                     VVKEVIPAELLDDQTKYYINPTGRFVIGGPQGDAGLTGRKIIVDTYGGYARHGGGAFS
                     GKDATKVDRSASYAARYIAKNIVAAGLARKAEVQLAYAIGVAQPVSISINTFGTGTVP
                     EEELIAAVRENFDLRPAGIIEMLDLRRPIYKQTAAYGHFGRTDVDLPWEHTDKVDALK
                     ASLAK"
     gene            3826..5298
                     /locus_tag="LLC22_002468"
     CDS             3826..5298
                     /locus_tag="LLC22_002468"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331067.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5435691.1"
                     /translation="MKKETNVTLVTVSIFIATFMTAIEGTIVTTAMPTIVGSLHGMEI
                     MNWVFSIYLLTNAMLTPIYGKLADKVGRKPIFIFGTLLFIIGSLFCGLSQSMIGLIAA
                     RAIQGMGAGAMMPVALTIIGDLYSIEKRAKVLGLNSSAWGIASVFGPLAGGFIVETIS
                     WHWIFFINVPIGILLIILIWLYLNEPKIIHESKPMDIFGSFSLMAMLVSLLLGFQLLG
                     DEGMSPLVSALLLGSIVMLGIFVFAEKRAKDPVIMMHLFKNPLFVVVNLAAALASGFL
                     MGIDVYIPMWMQGVLGLNAAIGGLVLAPLSLVWMVGSFLASKWMTQMKTHWVLRIGLL
                     IAAIGGAWLYLMPFRSNYLWFFAISTVIGIGLGVTMTTSTVSAQNSVSRDQLGVATSF
                     NTLVRTIGQTVMVSIFGLLINGVTKRELAAANLTNDADIMNKLVNPQTAKYIDADILL
                     PLRKILYDGLHSVYLVGLLLVIIALVLTLFVHEKSGKIKQ"
     gene            5381..6169
                     /locus_tag="LLC22_002469"
     CDS             5381..6169
                     /locus_tag="LLC22_002469"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344918.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="esterase family protein"
                     /protein_id="HBK5435692.1"
                     /translation="MAFIQANIYSNVLEMEVNLNVILPQTTKKVIGTSSEQETTDIPV
                     LYLLHGMGGNHSVWERRTSIERYVANYGLAVIMPSTDLGWYTDTVYDMKYWTFIAEEL
                     PEICHELFPQLTRKREKTYAAGLSMGGYGALKLGLAKSENFAAVISLSGAVSVGNRMD
                     DLLMVRKASFWEGIFGPLDQIEGSKNDPQYLLKELVKSGKPVPRFYMACGESDFLYQA
                     NQEMVSAMQEQGLAVTFEQGPGDHNWIFWDQWIQRALAWLMEEK"
     gene            complement(6236..6904)
                     /locus_tag="LLC22_002470"
     CDS             complement(6236..6904)
                     /locus_tag="LLC22_002470"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002285876.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator
                     C-terminal domain-containing protein"
                     /protein_id="HBK5435693.1"
                     /translation="MEIKLSQAIIIQAAFDILAETQALSQLSMRNIANRIHVQAPALY
                     WYFKNKQQLLQKMAETMEEELALPDPTLPWNEQLLQYMENYYDLYTRFPCGAELEINT
                     VPAFPSRLEHLEQMIQLLVREGFSVTQSHQAIASLHNLLIGQLMDQQHEQQLRQKIMD
                     GNEFLKETVLFMRNYVVENQLEGFKESMQSHAELNEKALFLTSAQTYIEGLCQQNKRR
                     ENEQ"
     gene            7019..8731
                     /locus_tag="LLC22_002471"
     CDS             7019..8731
                     /locus_tag="LLC22_002471"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435694.1"
                     /translation="MKLILRHAKKYKVAVFISLLSVAVMVAAALWQPKLLQQVLEAII
                     TEDNDEMKTIGIYLISLALLGLAAGVTNTIFSAKVAQGVSADIREEAFRKIQTFSFGN
                     IEQFSAGNLVVRLTNDITQIQNLVMISLQSLFRIPFLFIGAFILAMITMPQLWWIIVA
                     LIVTVFLITALSFTRMGKHFMIIQKLIDRVNSIAKENLLGIRVVKSFVQEENQLKSFS
                     KVSEDLTKHNIIVGTLFSVMIPSFMLAANLAVVGAIFFVSDLVKDDPTLIGGIASFMN
                     YLMQIMMAIIIGGMMMMMTSRAAVSLKRIAEILDAEPDLTYLDVPEQELTGSVTFDHV
                     SFRYPGEDTDTLKDISFSIKPGEMVGIVGATGAGKSTLAQLIPRLFDPTEGKVEVGGV
                     DLRQVNEKSLRQTVSFVLQKAILFSGTIAQNLRQGKKNATEKEMEHASSIAQAKEFIE
                     KLSDRYEAPIEERSSNFSGGQKQRLSITRGVIGNPKILILDDSTSALDARSEKLVREA
                     LDRDLKGTTTIVIAQKIASVVKADRILVLDEGRLVGEGTHEELVAGNRVYQEIFETQK
                     GTEE"
     gene            8734..10506
                     /locus_tag="LLC22_002472"
     CDS             8734..10506
                     /locus_tag="LLC22_002472"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299072.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435695.1"
                     /translation="MTDLIKASKFFYHYLKRYKLSFFFIFITVIIATYLQVKAPQYIG
                     EAFQELANYVGGLMQGVDDKSKFVSVIWKLLLFYVLASAANFIYSILFTQVVGKSTNR
                     MRIGLFNKLEKLTIRFFDSHQDGEILSRFTSDLDNIQNSLNQALLQVITNAVLLVGIL
                     IMMFRQNVELAWATIASTPVAVLIAVLIIRKARKYVDLQQDEVGKLNGYMDEKISGQR
                     VIITNGLQEETIEGFLEHNQSVREATFKGQAYSGLLFPMMQGMSLVNTAIVIFFGGWL
                     ALNGDLERSVALGLVVTFVQYSQQYYQPLMQISSGYSMIQLAITGARRLNEIFDEKDE
                     VKPENGKAFDGVEKGLALQHVDFGYSPEKLVLKDVSINVDKGEMVALVGPTGSGKTTI
                     MNLLNRFYDVNDGSVVIDGIDIRDYDLDALRRHVGIVLQESVLFSGTIKDNITFGKPD
                     ASDEEVINAAKQANIHDFIMTLEKGYDTEISEENNLFSTGQKQLISIARTIITNPSLL
                     ILDEATSNVDTVTEARIQKAMDEAIKGRTSFVIAHRLKTILNADRIVVLRDGEVIEEG
                     SHHELLAENGFYAELYHNQFVFES"
BASE COUNT         3033 a         1926 c         2454 g         3162 t
ORIGIN      
        1 aagttatcca tggaggttta gctcagctgg gagagcatct gccttacaag cagagggtca
       61 gcggttcgat cccgttaacc tccatatgag ccgttagctc agttggtaga gcatctgact
      121 tttaatcaga gggtcacagg ttcgagccct gtacggctca tatttttgcg ggtgtggcgg
      181 aattggcaga cgcactagat ttaggatcta gcgccttacg gcgtgggggt tcaagtccct
      241 tcacccgcat aatttaagtt ttacatgccg gcttagctca gttggtagag catctgattt
      301 gtaatcagag ggtcgagggt tcaagtcctt tagccggcat ctttaaacac gcggaaatag
      361 ctcagtggta gagcaccacc ttgccaaggt gggggtcgcg ggttcgaacc ccgttttccg
      421 ctttgccaaa gcaatcgcgc cggggtggcg gaactggcag acgcacagga cttaaaatcc
      481 tgcggtgagt gatcaccgta ccggttcgat tccggtcctc ggcatttcaa atatgcgccc
      541 atagctcaac tggatagagt gtttgactac ggatcaaaag gttaggggtt cgactcctct
      601 tgggcgcgtt aattaaacgg gaagtagctc agcttggtag agcacttggt ttgggaccaa
      661 ggggtcgcag gttcgaatcc tgtcttcccg ataattataa atttaaacac ggggccttag
      721 ctcagctggg agagcgcctg ctttgcacgc aggaggtcag cggttcgatc ccgctaggct
      781 ccatttcatt taaataatga atatcttttt cgcggtgtag ctcagctggc tagagcgtcc
      841 ggttcatacc cgggaggtcg ggggttcgat cccctccgcc gcgattttta agagcctgga
      901 cctttagctc agttggttag agcagacggc tcataaccgt ccggtcgtag gttcgagtcc
      961 tacaaggtcc attgtggcgt tgtaagtttc atatggagga ttacccaagt ccggctgaag
     1021 ggaacggtct tgaaaaccgt caggcgggta aaaccgtgca agggttcgaa tcccttatcc
     1081 tcctttttca tattatcgcg ggatggagca gtctggtagc tcgtcgggct cataacccga
     1141 aggtcgtagg ttcaaatcct gctcccgcaa ttaaaaacta aaaacactgg ttccgtggtg
     1201 taggggttaa catgcctgcc tgtcacgcag gagatcgcgg gttcgattcc cgtcggaacc
     1261 gccatgcggg tgtagtttag tggtaaaacc acagccttcc aagctgttgt cgcgagttcg
     1321 attctcgtca cccgctttta gttttttatg ggcctatagc tcagctggtt agagcgcacg
     1381 cctgataagc gtgaggtcga tggttcgagt ccatttaggc ccattagtac aaaatcttat
     1441 tggttttggg gaagtactca agtggctgaa gaggcgcccc tgctaagggt gtaggtcggg
     1501 aaaccggcgc gagggttcaa atccctcctt ctccgtttca atattttgtt ttacctggcc
     1561 cgttggtcaa gcggttaaga caccgccctt tcacggcggt aacacgggtt cgaatcccgt
     1621 acgggtcatt aatttaatat agttttacat ggaggattac ccaagtccgg ctgaagggaa
     1681 cggtcttgaa aaccgtcagg cgggtaaaac cgtgcaaggg ttcgaatccc ttatcctcct
     1741 ttttcatatt atcgcgggat ggagcagtct ggtagctcgt cgggctcata acccgaaggt
     1801 cgtaggttca aatcctgctc ccgcaattaa aaactaaaaa cattggttcc gtggtgtagg
     1861 ggttaacatg cctgcctgtc acgcaggaga tcgcgggttc gattcccgtc ggaaccgttt
     1921 ggctcggtag ctcagttggt agagcaatgg attgaagctc catgtgtcgg cagttcgatt
     1981 ctgtcccgcg ccattatgcg ggtgtagttt agtggtaaaa ccacagcctt ccaagctgtt
     2041 gtcgcgagtt cgattctcgt cacccgcttt tagtttttat gggcctatag ctcagctggt
     2101 tagagcgcac gcctgataag cgtgaggtcg atggttcgag tccatttagg cccatttatt
     2161 ttattggccc gttggtcaag cggttaagac accgcccttt cacggcggta acacgggttc
     2221 gaatcccgta cgggtcatgg aagatacttt ttgagtatct ttttcttttt atctgaaaga
     2281 atgattttaa aaagcttagc agagttatct ttatggatga ttgtgctaag cttttttgga
     2341 cagttctaat gtaaaatatt tttatatttt ttaagcaaaa aaatgaaaaa atacgagcag
     2401 aaaactgttt tatctgctat acttggttcg ttgcaagttc ccgaaaggat ccgcaggacg
     2461 gagatgcctt gtaaccgaat ttaactaggg ggaatcatta taatggtaga aagacactta
     2521 tttacatcag aatctgtttc tgaaggacat ccagataaaa ttgctgacca aatcagtgat
     2581 gcaatcttgg atgcaatttt aaaacaagat ccaacagcac gagtagcgtg tgaaacgtct
     2641 gtaacaactg gtcttgtttt agtatttgga gaaatatcta cgacggcata tgtagatatt
     2701 caaaaagtcg tacgggaaac aataaaagaa attggttata cacgtgcaaa attcggattt
     2761 gatggagata cagcagctgt attggttgcg attgatgaac aatctcctga tattgctcaa
     2821 ggagttgatg aagcacttga gatccgggat gaagataaaa aagacgtatt agatgagatt
     2881 ggtgctggtg accaaggttt aatgtttggg tttgctgtag atgaaacacc agaattgatg
     2941 cctttaccaa tcgctttgag tcatcgtctg gtacgacgct tggcagattt gcgtaaatca
     3001 aatgaattaa cgtatttacg tccagatgca aaatctcaag taacggttga atatgatgat
     3061 caaggacaac cggaacgcgt agatacaatc gttatttcaa cacagcatga tgatgcagta
     3121 gataatgaaa caattcgtca tgatgtcatc gaaaaagtag tgaaggaagt tattccagct
     3181 gaattattag atgatcaaac gaaatattat atcaatccga ctggccgatt tgtcattggt
     3241 ggtcctcaag gggatgccgg attaacagga agaaaaatca ttgttgatac gtatggcggt
     3301 tatgctcgtc atggtggcgg tgctttttct ggtaaagatg cgacaaaagt tgaccgttct
     3361 gccagctatg ctgcacgtta tattgctaaa aacattgttg cagcagggct tgctcgcaaa
     3421 gcagaagtac agctagctta tgcgattggt gttgctcaac ctgtttcgat ctcaatcaat
     3481 actttcggta ctggaacggt tccggaagaa gaactgattg ctgcagtgag agaaaacttc
     3541 gatcttcggc cagcaggaat catcgagatg cttgatttgc gtcgtccgat ttacaaacaa
     3601 acagctgctt acggtcattt tggtcgtaca gatgtagatt tgccttggga acatacggac
     3661 aaagtagatg cgttgaaagc aagtttagca aaataagtta tattcagctg gaacgatcgc
     3721 caagtggtgg ttgttccagc tttttttatg gcagttaacc tcttgaaaaa gatagtaatt
     3781 atttatctat ttttagatcc tgtcataatg aaagggagga ataagatgaa aaaagaaaca
     3841 aatgttactt tggtcacagt gagtattttc attgcaacgt tcatgacggc tattgaaggt
     3901 acaatcgtaa caaccgctat gccaacgatt gtcggttcat tacatggaat ggaaatcatg
     3961 aactgggtat tttcgattta tttgctgaca aacgctatgc ttactccgat ttacggaaaa
     4021 cttgcggata aagtgggacg gaaaccaatc tttatttttg ggacattatt gtttattatc
     4081 ggttcgttat tttgcggttt atctcaaagc atgattgggt tgattgctgc tcgtgcgatt
     4141 caagggatgg gtgctggggc aatgatgcca gtagctttga cgatcatcgg cgatctttat
     4201 tctattgaaa agcgagcaaa agttttaggt ttgaatagtt cagcctgggg gattgccagt
     4261 gtttttggac cgcttgcggg aggattcatc gttgaaacga tcagctggca ctggatcttt
     4321 tttatcaatg tgccgatcgg aattctatta attattttga tttggctata tttaaatgaa
     4381 ccaaaaatca tacatgagtc taaaccaatg gatatttttg gtagttttag tttgatggcc
     4441 atgcttgtct cattgctgtt agggttccaa ttattaggag acgaaggaat gagtccgctt
     4501 gtttctgctt tgctgctagg tagtatcgta atgttaggta tttttgtttt tgccgaaaaa
     4561 agagctaaag atcctgtcat catgatgcat ttattcaaaa atccactatt tgttgtggtc
     4621 aacttggctg cagcattggc tagtggtttt ttgatgggaa tcgatgttta tatccctatg
     4681 tggatgcaag gtgtattagg gctgaatgca gcaattggtg ggctggtatt agcaccatta
     4741 tcactagtct ggatggtcgg ttctttcctt gcaagcaagt ggatgactca aatgaaaact
     4801 cattgggtct tgagaattgg actactaatc gcagctattg ggggcgcttg gttgtatctt
     4861 atgcctttca gaagtaacta tttatggttt tttgctatat caacggtcat cggtataggc
     4921 ttaggtgtga ccatgactac ctcgactgtc agtgcacaaa atagtgtatc tcgtgaccag
     4981 cttggtgtag caacttcttt taatacgtta gttcgaacaa ttggtcaaac agtcatggtt
     5041 tctatttttg gtttattgat aaatggggta actaaacgag aacttgcagc agcaaattta
     5101 acaaatgatg cagatatcat gaataaactg gtgaatccac aaacggctaa atatattgat
     5161 gcggatattt tgttaccatt aagaaaaatt ctttatgatg ggttacattc cgtttatcta
     5221 gttggcttgt tactcgtgat cattgctttg gtcttaacgc ttttcgttca tgaaaaaagt
     5281 ggtaaaataa aacagtagtt tcggttaaga tatgtacgta gccgaatcat tcaaatttaa
     5341 agttattcaa aaataacttc ttactaagga aggcgaaaat atggcattta ttcaagcaaa
     5401 tatttattcg aatgtgttag aaatggaagt caatctaaat gtgatactac cgcaaacaac
     5461 aaaaaaggtg attggcacca gttcagagca agagacaacg gatatacctg ttttatattt
     5521 acttcatgga atgggtggca atcatagtgt atgggaaaga cgtacgtcga ttgaacgtta
     5581 tgtagcaaac tacggattag ctgtcatcat gccatctact gatcttggct ggtacacaga
     5641 tacagtttat gacatgaagt attggacatt cattgcagaa gagctacctg agatttgtca
     5701 tgaattattc ccgcaattaa caagaaaaag agaaaaaaca tatgccgctg gattatcgat
     5761 gggcggatat ggcgcgttaa aactaggcct tgcaaaatca gaaaatttcg cagcagtaat
     5821 ctctctttca ggcgctgttt ctgtaggaaa tcgaatggat gatcttttga tggttcgtaa
     5881 agcatctttt tgggaaggga tctttggacc attggatcaa atcgaaggtt caaaaaatga
     5941 tccgcaatac ttattgaaag aactagtaaa aagcggaaaa ccagttccaa gattttatat
     6001 ggcttgtggg gaatctgatt ttctttatca ggcaaatcag gaaatggtat ctgctatgca
     6061 ggaacaaggc ttggcggtca cctttgaaca aggacctggc gatcataact ggatcttctg
     6121 ggaccaatgg attcaacgtg cattggcgtg gctaatggaa gaaaaataaa aaaagagtct
     6181 taaaaagata gctcctatag agatcacaaa catagtgatc tctataggag cttttttact
     6241 gctcgttttc tcttctttta ttttgttggc ataagccttc aatataggtt tgtgcactcg
     6301 ttagaaagag tgctttttca ttcaattctg catgggactg catactttct ttaaatccct
     6361 ctaattgatt ttcaactaca taattacgca taaatagaac tgtttctttc aaaaattcat
     6421 ttccgtccat aattttttgt cgaagctgct gttcatgctg ctgatccatt aactgtccaa
     6481 tcaataaatt gtggagagag gcaatggcct gatgactttg ggtgactgaa aatccttcac
     6541 gaacaagtaa ttggatcatt tgctccaaat gttctaatcg actcggaaaa gcgggcacag
     6601 tattgatttc taattctgcc ccacaaggga aacgtgtata aaggtcatag taattttcca
     6661 tatactgcag caactgttca ttccaaggca aagttggatc tggaagcgct aattcttctt
     6721 ccattgtttc agccattttt tgcaagagct gttgtttgtt tttgaaatac caatataaag
     6781 caggtgcttg aacatgaatt ctgtttgcga tgtttcgcat ggaaagctgc gaaagagctt
     6841 gtgtttcagc caggatatca aaggcggcct gaatgatgat tgcttgagaa agctttattt
     6901 ccattttatc aacctcgtgt attgcattat ctttttaaac atggtaaatt gttagtcggt
     6961 ctaattttac agtgttaaat tagtcctgtc aatttaaaca aaggggtgta atcaacgaat
     7021 gaaattaatc ttacgacatg cgaaaaaata taaagtagct gtttttattt ccttgctgtc
     7081 cgtagcagtc atggttgcag cagcattatg gcaacctaag ttactacagc aagtattgga
     7141 agctattatt acagaagata atgatgaaat gaaaacaatt ggtatttacc tgatcagtct
     7201 ggctttgcta ggattagccg caggtgtaac gaacacgatt ttctctgcaa aagtagctca
     7261 aggcgtaagt gcagatatcc gagaagaagc atttcgaaag atccagacat tttcatttgg
     7321 aaatatcgaa cagttctctg ctggaaatct tgttgttcgt ctaacaaatg atatcacgca
     7381 aatccaaaat ttagtgatga tttctttgca atcacttttt cgaattccat tcttatttat
     7441 tggtgccttc attttagcta tgatcacgat gccgcaatta tggtggatca tcgtagcgct
     7501 tatcgttacg gtatttctga ttacggcact ttcatttaca aggatgggca agcacttcat
     7561 gatcattcaa aaactgattg atcgtgtgaa tagcattgca aaagaaaact tactagggat
     7621 tcgtgtagtg aaatcttttg tacaagaaga aaaccaattg aagtcattca gcaaagtaag
     7681 tgaggactta acaaaacaca acatcatagt cggtacatta ttttctgtga tgatcccgtc
     7741 cttcatgctg gctgccaatt tggctgtggt tggggcgatc ttttttgtga gcgatcttgt
     7801 taaagatgat cctacgttaa ttggtggaat tgcttcattc atgaactact tgatgcagat
     7861 tatgatggca atcattattg gcggaatgat gatgatgatg acttcaagag cagccgtatc
     7921 gctgaagcgg attgcggaaa ttttagatgc tgaaccagat cttacttatt tagacgttcc
     7981 agaacaagag ttgacgggtt ctgtcacttt tgaccatgtt tcttttcgtt atcctggtga
     8041 ggatacagat acgcttaaag atatcagctt ttctatcaaa cctggagaaa tggttggtat
     8101 cgtcggggcg actggtgccg ggaagtcaac actagcacaa ttgatccctc gtctatttga
     8161 tccgacagaa ggcaaagttg aagtaggtgg tgtagatctt cgtcaagtaa atgaaaagag
     8221 tttaagacaa acggtttcct ttgttttgca aaaagcaatt ttattctcag gaacgattgc
     8281 tcaaaacttg cgccaaggga aaaagaatgc aacagaaaaa gagatggaac atgcttcttc
     8341 tattgctcaa gcaaaagaat tcatcgaaaa gttatctgat cgttacgaag caccaataga
     8401 agaacgtagc agtaactttt ctggtggtca aaagcaacgt ttatccatta ctcgtggcgt
     8461 tatcggtaat ccaaagatct tgatcctaga tgacagtacg agtgcactgg atgctcgctc
     8521 tgaaaagctg gtccgagaag cactcgatcg agatttgaag ggaacaacga cgattgtcat
     8581 cgcacaaaaa attgcttctg ttgtcaaagc agaccgcatc ttagtattgg atgaaggcag
     8641 attagtcggc gaaggaaccc atgaggaatt ggtagctgga aaccgtgtct atcaggaaat
     8701 ctttgaaact caaaaaggaa cggaggagta agtatgactg atctaataaa agcaagtaaa
     8761 tttttctatc actatttgaa gcggtacaaa ctctcctttt tctttatctt tatcacagtg
     8821 atcattgcta cctatctaca agtaaaggca cctcaataca tcggggaagc ttttcaagaa
     8881 ttagctaatt acgtaggagg cttgatgcaa ggcgtagacg ataaaagcaa atttgtttct
     8941 gtaatatgga aactcttgct gttttatgta ctagctagtg cagccaactt tatctatagt
     9001 attttgttca cacaagtagt agggaagtca acgaaccgaa tgcgtatcgg tctattcaac
     9061 aaattggaaa aattgacgat ccgtttcttt gattctcatc aagacggtga aattttaagt
     9121 cgttttacca gtgacttaga taatattcaa aatagtttga accaagcttt gcttcaagtc
     9181 atcacgaatg ctgttttact tgtcgggatc ttgatcatga tgttccgcca aaatgtagag
     9241 ttagcttggg ctacaattgc ttccactcca gtagccgttt tgatagctgt cttgattatc
     9301 cgcaaagcac ggaaatatgt ggatcttcag caagatgaag tggggaaact aaatggttat
     9361 atggatgaaa aaatcagcgg acaacgtgtc atcatcacaa atggcttaca agaagaaacg
     9421 attgaaggat tcttagagca taatcaaagt gttcgcgaag caaccttcaa aggacaagct
     9481 tattctggtc tactatttcc gatgatgcaa ggaatgtcac tggtcaatac agcgatagtt
     9541 atctttttcg gcggctggtt agcattaaat ggtgatttgg aacgttcggt ggcattaggc
     9601 ttagttgtga cattcgtcca gtattcacaa caatattacc aaccactgat gcagatttca
     9661 tctggataca gcatgatcca attagcgatt acaggggcaa gacgattgaa tgaaatattt
     9721 gatgaaaaag atgaagtcaa accagaaaac ggtaaagcat ttgatggtgt tgaaaaaggt
     9781 cttgcgttgc agcacgtaga ttttggttat tctccagaaa aactagtctt gaaagatgtc
     9841 tcgatcaatg tggacaaagg agaaatggtt gctcttgttg gtccaacagg atcggggaaa
     9901 acgacgatca tgaatctgct aaaccgtttt tacgatgtca atgatggttc agtagtcatc
     9961 gatggaatag atatccgaga ttatgatctt gatgcattac gtagacatgt aggaatcgtt
    10021 ttgcaagaat ctgtattgtt ctccggaacg atcaaagaca atatcacatt cggcaaaccg
    10081 gacgcttcag atgaagaagt catcaatgca gcaaaacaag cgaatattca tgacttcatc
    10141 atgacgttag aaaaaggtta tgatacagag atatccgaag aaaataactt attcagtaca
    10201 ggtcaaaagc agttgatcag tattgctcga acgatcatca caaatccatc tttattgatt
    10261 ttggatgaag caacaagtaa tgtagacacg gtaacagaag caaggatcca aaaagcaatg
    10321 gatgaagcaa tcaaaggaag aaccagcttt gtgattgctc accggctgaa aacaatcttg
    10381 aatgcagata gaatcgttgt cttgcgtgat ggggaagtca ttgaagaagg cagtcatcat
    10441 gagttattag cagaaaatgg attttatgcg gaactttatc ataatcaatt tgtatttgaa
    10501 agttaaatta aaagaacctc gttataacgg ggttcttttt atatatttta tgttgtttgt
    10561 ttttataagg ggcag
//
LOCUS       DAFBVQ010000080        10088 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.083, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000080 DAFBVQ010000000
VERSION     DAFBVQ010000080.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 10088)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 10088)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..10088
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.083"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..144)
                     /locus_tag="LLC22_002473"
     CDS             complement(<1..144)
                     /locus_tag="LLC22_002473"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302255.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine desulfurase"
                     /protein_id="HBK5435696.1"
                     /translation="MLNILSSGSAALENRSSLNSELRELDYFFEAHPMIKEKIDSFVT
                     IDDL"
     gene            complement(169..354)
                     /locus_tag="LLC22_002474"
     CDS             complement(169..354)
                     /locus_tag="LLC22_002474"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435697.1"
                     /translation="MTKALIFDFDGTMIDSEWMFYESIHHYLLKPIYWSSSAIKFLLQ
                     TINKVLGRQQNCPFMKG"
     gene            581..1854
                     /locus_tag="LLC22_002475"
                     /pseudo
     CDS             581..1854
                     /locus_tag="LLC22_002475"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="frameshifted; internal stop; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
     gene            complement(1961..2992)
                     /locus_tag="LLC22_002476"
     CDS             complement(1961..2992)
                     /locus_tag="LLC22_002476"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302261.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435698.1"
                     /translation="MFLEIHDLNLFFDEKQILAIDEIQIEKGELVTLLGPSGCGKSTL
                     LRCITGLEQPKSGEIVLDNENIADKPTKDRNIGFVFQQYALFPTMTVFENVAFGLKVK
                     KLSPEVIQEKVFEMLSLVDMTEQADKNVQFLSGGQRQRVALARSLVTEPKVLLLDEPL
                     SALDARIRKQLQRDLRAIQQSLGMTMIFVTHDQEEAMRISDRIFVMEAGRVAQVSTSK
                     ELYQNPQSRFVAEFIGNYNRFEWYELNQYTHEFSAKGNRCIYYLRPELIQFEPVPQGV
                     KIPVLWKESFILGNIQRYVFQTLEGKEILVDRLNDREEKISDALYIQLKDILAIPVEI
                     DTQHFAQQS"
     gene            complement(2999..3829)
                     /locus_tag="LLC22_002477"
     CDS             complement(2999..3829)
                     /locus_tag="LLC22_002477"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435699.1"
                     /translation="MKKLIKPILFCFVLYYLLPIIGTILYASSTKWSKSLLPSDFTLQ
                     WFQQLLTDREFIAAVGRSLLLAGVVLVTILLLMIPTIIWIHLYFPRLNRWLEKLLLLP
                     YALPGVILVTALLRTYAETGIPMFVVLVGALFITALPIVYLSLNNQMRLINLKELVDA
                     AETLGAPMSTIIIQVLFPNIRIGVTLVSLMIFSSVFGEYMLTNLLIGGRFQTVRIYML
                     RRMNENGHLASAVMVLYLLFMVGIALTTFMLTYRQKQQLSLKQTREEKQSKKKPLKEL
                     "
     gene            complement(3826..4641)
                     /locus_tag="LLC22_002478"
     CDS             complement(3826..4641)
                     /locus_tag="LLC22_002478"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK5435700.1"
                     /translation="MKEMKKRLVLVPASFIFCAFLLLPLLFMVLCSLHSDLTNQWTLA
                     NYSDIFSNKYYTQAFVNSVLIAVSSSVIGLIGTFILCLCLMNLSTKLQEKITFVSNLA
                     ANFAGIPLAFSFIILLGNVGVLKMILPFLADFNLYSWWGLTITYTYFQIPLGVLFLYP
                     SMKEVKKEWLESAQLLGASSAYAWFKVALPFLRPSIASTFVILFANGMGTYETAYALT
                     SSNVNLLTIRIAALVSGDVFAKPNLGSALAVALGVLLVTAMLIIQKKGKVVQT"
     gene            complement(4638..5462)
                     /locus_tag="LLC22_002479"
     CDS             complement(4638..5462)
                     /locus_tag="LLC22_002479"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302267.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline phosphatase family protein"
                     /protein_id="HBK5435701.1"
                     /translation="MQSRLDKLIVVILDGCRYDTAVAQLGFMNHLVEHQQASLLKVKS
                     ELPSNSRPLYEVLMTGVPAYENGIYSNYHAQRSKEWSLFELVKEAGGKTGAAAYHWYS
                     ELYNQAPYNRLVDRIQHQEERLIQHGIFYSEDTYPDSHLFADAHYLVNQYQPDFLVVH
                     SMNIDDVGHKFTADSHEYAAAVNQADRLLAIYLPEWLQKGYQVVVTADHGMDAHGLHG
                     GSLAAHREVPFYLISNKRQKLKEQTVPQLLAAPLFCWLLGIAPSEKMQDIQELMRG"
     gene            complement(5452..6552)
                     /locus_tag="LLC22_002480"
     CDS             complement(5452..6552)
                     /locus_tag="LLC22_002480"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347701.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="extracellular solute-binding protein"
                     /protein_id="HBK5435702.1"
                     /translation="MKMNEKIRNMTIGLFCAATVSILLTGCVSGEATKQSAAADDSLD
                     TIIEKAKEEGEIASLGMPDTWANWVGTWNDLEKEYGLSHVDTDMSSAEELAKFESEGK
                     NGTADIGDVGISFGPLAESKELTLPYKTNYWEEIPDWAKDDDGDWLLSYTGTISFITD
                     KENVKQAPTSWKELQEGDYQVSVGDVTIANQAQFAVLAAAIANGGDEKDIQPGLNYYK
                     KMAEKGRLSTVDASVANLEKGEIDVAVVWDFNGLNYRDQIDSERFEVTVPTDGSIISG
                     YTTLINKNAPHPNAAKLAREYILSDEGQINLAKGYARPIRKVELPKEVAEKLLPEDAY
                     EAAVPVEDNEAWNKTSVELPELWQAEVLTYAK"
     gene            6730..7515
                     /locus_tag="LLC22_002481"
     CDS             6730..7515
                     /locus_tag="LLC22_002481"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326109.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidinol phosphate phosphatase"
                     /protein_id="HBK5435703.1"
                     /translation="MQYYDQHLHTYFSFDSEEKFENYLAYQPEFFVSTDHFDLNNPST
                     GKDDIPDYPAYINKLDSLKETYSTKFLRGIEIGVVPGQEERIVDYLAQHPYDLKLVSI
                     HQNGRFDYMDDVVLTKDPIQTTKEYFDQMLQVLTDFPEGDILTHFDYGLRRFTFTAEE
                     FAEHFEAQLLTIFKKVVERELAMELNAKSFLKYGNEDLYRYAVPLYQSVGGKLFTLGS
                     DAHVAEDYQLGFKKMSQLLADCQVEKLLVIQGKERRLTPLPIL"
     gene            7548..7931
                     /locus_tag="LLC22_002482"
     CDS             7548..7931
                     /locus_tag="LLC22_002482"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hydrolase"
                     /protein_id="HBK5435704.1"
                     /translation="MSNLWDYNQEAPIHYLIARHWDALKIEAVCRSLLAAVPKQQLEN
                     FLVADSLQREKVQAYFAAFKDQPLEYLHAQFHLFYQVAAPDDYNDLRGQLQLTFQADE
                     TAYTVLLGMARLGDQAKVEWRIFDI"
     gene            8007..8138
                     /locus_tag="LLC22_002483"
     CDS             8007..8138
                     /locus_tag="LLC22_002483"
                     /inference="COORDINATES: protein motif:HMM:NF012387.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5435705.1"
                     /translation="MLVTDAGEIRLRLFPDQAPLAVANWRSLAEQGVYDNTPFGSCH"
     gene            8107..8343
                     /locus_tag="LLC22_002484"
     CDS             8107..8343
                     /locus_tag="LLC22_002484"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5435706.1"
                     /translation="MTTHLSARVIKEFVIQGGALDGSGDEAVSSYEGFFADEVHRGLY
                     HFNGALALGDHGPHTNGNQFFIVQNTKAQADLLM"
     gene            complement(8421..9392)
                     /locus_tag="LLC22_002485"
     CDS             complement(8421..9392)
                     /locus_tag="LLC22_002485"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002361027.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="radical SAM protein"
                     /protein_id="HBK5435707.1"
                     /translation="MEGTVLRIEQGSLHDGAGLRTVVYLKGCPLRCAWCSIPESQSKQ
                     IEKGFGQTMTAEEVMDEIEKDAVFYFHSDGGVTISGGEALVQADFAKEILQKSKYIGI
                     NTVLETSFCGAYNEIQKVAPYVDTLFVDVKMFTSKLHKQWTGLDNQQILKNIRRFLIE
                     YPNCEVRIRVPVVPGINMNLTELLTIACFVADLDRFVPLELLPYHCYGMHGYQALGLE
                     YPLADTPAPSPKEMFALADQLARTVPHLLVTALTKTFIYLLNPSFILWINERHSLAAA
                     SSRIELLLKSVSVFLRCFFEVNLSNEHWLNRYIFTVCRLSCDRCYDF"
BASE COUNT         3007 a         2317 c         1926 g         2838 t
ORIGIN      
        1 aagatcatcg atcgtcacaa aggaatcaat tttttcctta atcatcggat gtgcttcaaa
       61 aaaatagtct agctcccgca gttcagaatt gagactactc cgattttcca gtgctgctga
      121 tccgctgctc aaaatgttca gcatccactg gtctcccaac cgcttgactt atcccttcat
      181 aaaaggacag ttctgctgcc gtcccaacac cttgttgata gtctgcaaaa ggaattttat
      241 agccgaactg ctccagtaaa taggcttcag taaatagtga tgaatactct cgtaaaacat
      301 ccattcactg tcaatcatcg tcccatcaaa atcaaaaata agtgctttgg tcatcttctt
      361 tcccccttac ccaaaacaag caaaagctgt gtcctgctct ctctacagta tcagcataaa
      421 aactgccgtc tgaaaagtca aaggtgaaag aaatgtggcg ctataatttc taggactgat
      481 agtaaatcat tctatcagtc cttttgagca taaaaaaaca aaacatacag aagctccgtt
      541 agaattgaat caccacaaca caatcaaagg agcgttctgt atgcctgatc ttcatcttat
      601 caaactatta ctaggaatca aagatggaaa cattcaaatc actcatgtcg agaagaaaaa
      661 aatacattca atcaacagta tcgttgtttc tgccacgctc attaaaacga ttcagccctg
      721 tcctcagtgt aaacaggtga atcaacatgg gctgatcgtt aagaacggaa agaaaaaatc
      781 gctggtcctt ctcaataagt gtgcgaatca acggacttat cttgctttgg caaagcaacg
      841 gtacctctgt cgtggctgtc acacctattt tacggcgaat acctacattg ttgaaaaaaa
      901 ctgttttatc gccaaacaag tacattataa aatattggag gaattgactg aaaaacaagc
      961 aatgacgacg atttctaaac attgcggcgt ttcttggtca accgtttcgc gaacactcgc
     1021 ttctctgctc cccatgacaa acgtgaaaat aaattggttg cctcgctgtt cattggtaga
     1081 tgaatttcgt tcattgaaaa atcaagtcgg tccctattct ttttcttgta tggatggcga
     1141 tactgggaaa ttactggata ttcttccttc acgtaagaag aaagatctca tttcttattt
     1201 tatgcaattt gaacgacgtg cacgtttaaa cgtaaaaata ctcgtaacag atatgaacgc
     1261 ctcttatgct ttgctgataa aagagtgctt tcctcatgcc aaactcgttg tggatcgctt
     1321 tcacatcgtc aagcacctca ttcgcagttt taaggatatt tgactatgag tcatgaaaag
     1381 cttcgaccga aacgatccaa tacaagccaa acactatcga caagtgaagg ctttatctcg
     1441 acttctgatc aaacgacagg acacgcttgt ttatgataaa tggacaaaat ggcgtaattt
     1501 tggttgggcc tatttaaccg aaagtgaagt cgtagaacgt ctactttcta cttctgatga
     1561 actacgaata gcttatgctt actatcaaga aattcttcaa gctttttatg acaaagaagc
     1621 ggacatcttc tttcagcttg taaaaacaat gcccaagtcg gttccaagag aactgcatca
     1681 tataaaaaaa gcgtttataa actatgaatc cggcattcgt ttagccttag agttgcctta
     1741 ctcaaatgtc aaaatagaaa atctgcatac ccacatcaaa gcattgaaac gaatagctta
     1801 cgggttagga tgagaaccag aattttctta atcaatcatc tgatcactta ttaaacataa
     1861 aaaaacatct aaagcagaaa atcaattcta ccttagatgt tcttatatca ctctatcagt
     1921 cctatttgac aaagagccag aaatgtttgc cgactataca ctagctttgt tgtgcaaaat
     1981 gctgagtatc aatttccaca gggattgcta gaatatcttt cagctgaatg tataaggcat
     2041 cgctaatttt ctcttcccga tcgttcaacc gatccactaa aatttctttg ccctccagcg
     2101 tttgaaaaac ataccgttga atgttgccta aaataaatga ttccttccat agaaccggaa
     2161 tcttaacccc ctgaggaacc ggttcaaatt gaatcagctc cggtcttaaa taataaatgc
     2221 agcgattgcc cttagcggaa aactcgtggg tatactgatt cagctcatac cattcgaaac
     2281 gattatagtt gccgataaat tccgcaacaa atcggctctg aggattctga tacaattcct
     2341 tcgaggtgga aacctgagcc acccgcccag cttccatcac aaaaatccga tcactgattc
     2401 gcatcgcctc ttcttggtca tgagtcacaa aaatcatcgt catccctagc gattgctgga
     2461 tagcgcgcaa atcccgctgc agctgttttc taattcgggc atccaaagca cttaatggct
     2521 catccagcag caggactttc ggttcagtga ccaatgagcg agccagtgcc acccgttgtc
     2581 gttgaccgcc agaaagaaac tggacatttt tatctgcctg ctccgtcata tccaccaatg
     2641 atagcatctc aaaaaccttt tcctgaatca cctcaggact cagcttcttt accttcaaac
     2701 caaaggctac attttcaaaa acagtcatag ttggaaacaa tgcatactgt tgaaaaacaa
     2761 agccgatatt gcgatccttc gtaggcttat cggcaatatt ctcattgtcc agcacaatct
     2821 caccgctctt tggttgttcc aatcccgtga tacagcgcag caacgtagac tttccgcacc
     2881 cgctgggacc tagtaaagta accagctcac ccttttcaat ctgaatttca tcaatagcta
     2941 aaatctgttt ttcatcaaaa aacagattga gatcatgtat ttctaaaaac attttccgtc
     3001 acaactcctt taagggcttc tttttcgact gcttctcttc cctcgtctgc ttaagggaca
     3061 gctgttgctt ttgtcgataa gtcagcataa aggtagttaa agcaattccc accataaaca
     3121 gcaaatacaa aaccatcaca gcgctagcca aatggccgtt ttcgttcatc cgccgcagca
     3181 tatagatgcg taccgtctga aatcgaccgc caatcaacag gttcgtcagc atgtactccc
     3241 caaaaaccga agaaaaaatc atcagagaaa ctagggtcac accgatacgg atgtttggaa
     3301 acagcacctg gataataatc gtagacatcg gggcgcccaa ggtttctgct gcatccacta
     3361 attccttcag attaattaag cgcatctggt tgttaagact aagatagaca atcggcaacg
     3421 ccgtaataaa caatgcacct accaacacta caaacattgg gataccagtt tcagcatacg
     3481 ttcgaagcaa agccgttacc aaaatcactc ctggtaaagc atacggcagc aggagcagct
     3541 tttccagcca acgattcaaa cgagggaaat acaaatgaat ccaaataatg gtgggaatca
     3601 tcaacaacag aatcgtcacc aagaccacac ctgctaataa aagtgagcga cccaccgcag
     3661 caataaattc cctgtccgtc agcagctgtt ggaaccattg caaggtaaaa tcactaggta
     3721 aaagcgattt tgaccattta gtggagctgg catacaaaat cgttccaata atcggcagca
     3781 agtaatacag gacaaagcag aacaaaatcg gttttattaa ctttttcacg tctgcaccac
     3841 cttgcctttc ttttgaataa tcaacattgc cgttaccagc aggacaccta aagcgactgc
     3901 caacgcactg cctaaattag gcttggcgaa cacatctccc gacactaaag ccgcaattcg
     3961 aatcgttaaa agatttacat tactgctggt cagggcatac gctgtttcat aggtccccat
     4021 gccattagca aataagatga caaaggtgct ggcaatcgat ggtcgcaaaa aaggcaaagc
     4081 caccttgaac caagcatacg ctgatgaagc gcccagcaat tgtgcggact ccagccattc
     4141 ctttttcact tccttcatgc tgggatacaa aaacaagacc cctaacggaa tttggaaata
     4201 ggtatacgtg atggtcaatc cccaccaaga atacaaattg aagtccgcta gaaatggcaa
     4261 aatcattttc agcacaccta cattccccaa caaaataata aaagagaatg ccagcggaat
     4321 cccagcaaaa ttagctgcca aattggaaac aaaggtgatt ttctcctgca atttagtcga
     4381 tagattcatt aagcataaac ataaaataaa cgtcccgatt aacccaatca cactggagct
     4441 gacagcaatc agtacgctgt taacaaaggc ctgtgtgtaa tatttgttgc tgaaaatatc
     4501 actgtaattg gccaatgtcc actggttagt taaatcactg tgcaagctgc acagaaccat
     4561 aaaaagcagc ggcagcagta aaaatgcaca gaagataaag gaggcaggaa ccagaaccaa
     4621 gcgttttttc atctctttca tcccctcatc aattcttgaa tgtcctgcat tttctctgac
     4681 ggtgcaattc ctaataacca gcaaaacaat ggagccgcca gcagctgtgg tacagtttgt
     4741 tccttcagct tttggcgttt atttgaaatc aaataaaaag gaacttcacg atgtgcagcc
     4801 aagctgccgc catgcagtcc gtgcgcatcc atcccgtgat ccgcagtcac cacgacttga
     4861 taaccttttt gcagccattc aggaaggtaa atagccaata atctgtccgc ctgattaacc
     4921 gctgctgcat attcatgaga atcggcggta aatttgtgac cgacatcatc aatattcatc
     4981 gaatgtacga ccaaaaagtc tggctgatac tgattcacta aataatgggc atccgcaaat
     5041 aaatgcgaat cagggtaagt gtcctcacta taaaagatgc catgctgaat cagtcgctcc
     5101 tcctgatgct ggatgcgatc aaccaaacga ttataggggg cttgattgta caactcgctg
     5161 taccagtggt aagcggcggc tcctgttttt ccgccagctt ccttaactaa ttcaaacagc
     5221 gaccactctt tggatcgctg agcatggtaa ttactataga tgccattttc ataggctgga
     5281 acgccggtca tcagtacttc gtataacgga cgtgaattgc tgggcagctc actttttacc
     5341 ttcaataagc ttgcttgctg gtgctcaact aaatgattca tgaacccaag ctgggcgacg
     5401 gctgtgtcgt agcgacagcc gtctagtata actacaatca gtttgtcaag tctactttgc
     5461 ataggtcagt acctccgcct gccaaagctc tggaagctct acagaggtct tgttccaagc
     5521 ttcattgtct tcaactggca ccgccgcttc ataagcatcc tccggcagta atttttcagc
     5581 tacttcttta ggcagctcta ccttgcgaat aggtcgcgca tagccctttg ccaaattgat
     5641 ttgcccttca tcagataaaa tatattcccg tgctagcttt gccgcattgg gatgaggggc
     5701 atttttattg attaaggttg tatacccgct aatgatggag ccgtctgttg gcacagttac
     5761 ctcaaaacgc tcggagtcaa tttggtcacg ataatttagt ccattgaagt cccaaacaac
     5821 tgccacatcg atttcacctt tttcaagatt tgctacgctg gcatcaacgg tggacaaacg
     5881 gcctttttct gccatttttt tgtagtaatt cagacctggc tgaatatcct tttcgtcacc
     5941 tccgttggca atcgccgcag ccaatacagc aaattgtgct tggttggcaa tcgtcacatc
     6001 ccccacgcta acttgatagt caccctcttg cagctccttc cagctagtcg gtgcttgctt
     6061 cacattctct ttatcggtga taaaggaaat ggttcccgta tagcttaaca accaatcccc
     6121 atcatcatcc tttgcccaat ccggaatttc ctcccaatag ttggtcttat aaggtaaggt
     6181 taactctttg ctttcagcca acggaccgaa gctgataccg acatcaccaa tatcggcggt
     6241 tccatttttt ccttctgatt caaacttagc caattcttct gcactggaca tatccgtatc
     6301 cacgtgactt aagccgtatt ctttttcaag gtcgttccaa gtgcctaccc aatttgccca
     6361 agtatccggc attcccaagc tggcaatctc tccttcttcc ttggcttttt ctataatcgt
     6421 atctaaagag tcgtctgccg cagccgattg cttcgttgct tcacctgaga cgcagcctgt
     6481 cagcaggata cttactgttg ctgcacaaaa taaaccgata gtcatgttac gaattttttc
     6541 attcattttc attcattctt ctcccctttc gataattcca ttctaacaaa gctttgtaat
     6601 gagagaatca gtttcttgaa aaggtttcat gaacaatgta aaggttgtat atggtttgta
     6661 aatttcgacg aattcccgtt aaccttctaa agcttttgcg gtatgatagt agaaaaaagg
     6721 aggctcccta tgcagtatta tgatcagcat ctccacacgt atttttcctt tgattcagag
     6781 gaaaaatttg aaaactattt agcctatcag ccggagtttt tcgtttctac ggatcacttt
     6841 gatttaaaca atccatctac cggaaaagat gacattccgg attatccagc ctatataaac
     6901 aaactggact ctttaaaaga aacctattcc accaaatttc tgcgaggtat cgagattggc
     6961 gttgttccag gacaagaaga gcggatcgtg gattacctcg ctcagcatcc ttatgattta
     7021 aagctggtaa gtattcatca aaatggccgc tttgattata tggacgatgt ggttttaacc
     7081 aaagatccca ttcaaactac caaggaatat tttgatcaga tgttgcaggt cttgacggat
     7141 tttccagaag gagatatttt gactcacttt gattatggat tacgccgctt caccttcaca
     7201 gcggaagaat tcgcggagca ttttgaggct cagctgctaa cgattttcaa aaaggttgtt
     7261 gaacgagaat tggcgatgga gttaaatgcc aagagcttct tgaaatacgg caacgaagac
     7321 ctttaccgtt atgccgttcc tttgtatcaa agtgtcggcg gaaagctctt taccttaggc
     7381 tcggatgctc atgttgccga agattatcag ctgggcttta aaaaaatgag tcagctgttg
     7441 gcagactgtc aggtagaaaa gttgctagtc attcaaggaa aagaacgccg cctgacgccg
     7501 ctgccgattt tgtgattcct atataataga agaaagtggt gaaaaaaatg agcaacctgt
     7561 gggactacaa tcaagaggca cccatccatt atttaattgc gcgacattgg gatgcgttga
     7621 aaattgaggc ggtttgccga tccttgttag cagccgttcc aaaacaacaa ctggaaaatt
     7681 ttttggtggc tgacagcttg cagcgggaaa aagttcaggc ttattttgca gcctttaaag
     7741 atcagccttt ggaatatttg catgcgcagt ttcatctttt ttatcaagta gccgccccag
     7801 atgactacaa cgatttacga ggacagctgc aattgacctt tcaagcggat gaaaccgcct
     7861 ataccgtttt attgggaatg gctcgccttg gtgatcaggc gaaggtcgag tggcggattt
     7921 tcgatatttg atggcaggat caaggcgttt cagttgcaaa ccttcctctc tttcaattag
     7981 aaaaaccgca gcaggaagaa gtttgtgtgc tggtcaccga tgctggtgaa attcgtctcc
     8041 gcttatttcc tgaccaagct cccctggctg tagccaactg gcgctcccta gctgagcaag
     8101 gcgtttatga caacacacct ttcggctcgt gtcattaagg aatttgttat tcaaggtggc
     8161 gctttggatg gttctggtga tgaagctgtt tccagctatg agggcttttt cgctgatgaa
     8221 gtgcatcgcg gactttatca ttttaatggc gccttggcct taggggacca cggcccccac
     8281 accaacggca accagttttt tattgtgcaa aacacaaagg cgcaggctga cctgctaatg
     8341 taaagcaagc atacttggag cttggaggac taccggagct ggatggtcgt tatactgttt
     8401 ttggacaggt ataccaaggg ttagaaatcg tagcagcgat cgcagctcag ccgacaaaca
     8461 gtgaagatgt accgattgag ccagtgttca ttcgacaaat taacttcgaa aaaacatcgt
     8521 aaaaagacac tcactgactt cagcaaaagc tctattcttg agctggctgc agctagtgag
     8581 tgtctttcat ttatccataa gataaagctt ggattcaata aataaataaa tgttttggtt
     8641 aaagctgtga ccagcaaatg aggaaccgtg cgagccagtt gatctgccaa tgcaaacatt
     8701 tctttaggtg aaggcgctgg cgtgtctgcc aacggatact ccagtcccaa tgcttggtaa
     8761 ccgtgcatac catagcagtg gtacggtagt aattctaacg gtacgaaccg atcaagatct
     8821 gccacaaaac aagcaatcgt cagcagctcg gtcaggttca tattgatacc tggaaccaca
     8881 ggaactcgaa ttcgcacttc gcagttagga tactcaatta aaaagcgacg aatattcttc
     8941 aaaatttgtt ggttatctaa gccggtccat tgtttgtgga gcttgctggt aaacattttt
     9001 acatccacaa acaatgtatc cacataggga gctacctttt ggatttcatt ataagcacca
     9061 caaaagctgg tttccagtac ggtattgatt ccaatgtatt tcgatttttg caaaatttct
     9121 ttagcaaaat ccgcctgaac cagtgcctcg cctccgctaa tggtcactcc gccatccgag
     9181 tgaaagtaaa aaacagcatc cttctcaatc tcatccatta cctcttcagc ggtcatggtc
     9241 tggccaaatc ctttttcaat ctgcttgctt tgtgattcgg gaatcgaaca ccaggcacag
     9301 cgtaatgggc agccctttaa ataaacaacg gtccgtaaac cagcaccatc atgtagagaa
     9361 ccctgttcta ttcttaatac tgttccttcc atatagattt ttgaattaca cactagttta
     9421 aactaaaaca cacaaggaaa aacttaccat ttaatcataa aattagctca tataaatata
     9481 ctaggatgta aaatagactg gtcaaaatct ggtcaaaaaa gaggactaat acaggtagtc
     9541 ctcttttttg ttattttaat attctaaatc attttttatt ggtttattcc cttattcgat
     9601 gtagactcaa atcactatat cactagatat caaacggcgt catacggaat caaaaacatc
     9661 aaatttgacc tgttaaatgg tcattgaata acattcaaaa tcaataaaac ggagtcagac
     9721 acggagtcaa aaacgctgag agtaaaaaat atatacagcc ttgtaggtaa agtaccacag
     9781 ggctgtatat tttttatttc agattacctt aaatgattcc atttactttt tatctcattt
     9841 tttcctacta gttagtatca aatactctcc tattttctca ataaactatt tttggataca
     9901 tggtatctga aacagctaaa accttgtcat tacagcaaaa aatcacgtta tccagactgt
     9961 agacaaagtc cattttatgg atgatgtcta cagtcttttc ttttataata gatttatgaa
    10021 aacgaatgca aggagtgata gctatgatgt ctaaaaacaa tacgaatggt agaaatcaat
    10081 ttgcgatg
//
LOCUS       DAFBVQ010000081         9209 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.084, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000081 DAFBVQ010000000
VERSION     DAFBVQ010000081.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 9209)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 9209)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..9209
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.084"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            470..2107
                     /locus_tag="LLC22_002486"
     CDS             470..2107
                     /locus_tag="LLC22_002486"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435708.1"
                     /translation="MKKNKNQIIDIIFMLFLSFAYVIPLFMSMGIYHSVNQDTYFHLS
                     RIIGLDNVWSSPVNFNNFDHHGTMMNIFYPWLTLYPAFLFYKMMGNLVLSYNIYYFFI
                     TFLTMVVSYFSMKQIKNNRYISLLFSIIYTFSAYRAIDIFHRASLGEAVALTFLPLIL
                     MGCYEIYIRDYQKWYWLSIGMTLVVYTHLLSVAMVSVFIGGTLFLSFYFWDQKIARLL
                     SLLKATVLTFFLSAGFLIPFIQQSRAQELKVPLGKELSGMAPSDMLTHILNNNYNNYT
                     IGLFLFLGLIGAFIFIKKLTADDLFIFFLGVFVLFCSTNLFPWQLFNHTPVKSLQFVW
                     RLNGFSSLFIAYTMSIVIYYIFSTKNNSWKIMVFTFLALILHLSGVSNSIHANKDSLT
                     LIAPEDAVAIAENYNHTDYANKESIYHPDMINNDQYLLGNQEINPTTHFMSNKLTIEL
                     DNSNNKNTVLTTPIYRYKGQVASINGKLVQTKLSKFGTTELTIPPGINKVVITYQYTK
                     LAIASRYLSIVTLILFLLYRFTFSKQKQPRREVQHSH"
     gene            complement(2252..2992)
                     /gene="truA"
                     /locus_tag="LLC22_002487"
     CDS             complement(2252..2992)
                     /gene="truA"
                     /locus_tag="LLC22_002487"
                     /EC_number="5.4.99.12"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tRNA pseudouridine(38-40) synthase TruA"
                     /protein_id="HBK5435709.1"
                     /translation="MRNIKLTIEYDGKRYSGWQRLGDDDKTIQGKIEKVLHQMTNEEI
                     EIIGSGRTDAGTHARGQVANFKTNTEIGLAEMIDFMNRYLPRDIVIKRIEEMPERFHS
                     RYNAVGKKYSYYVWNNVIPSAFERNHSFYFPQELDMDKLNAACEKLVGTHDFIGFSAL
                     KKSKKSTVRTIDELSIERKGEMLHFTFVGDGFLYKMVRIIMGTLLEIGTGAMPIETID
                     EIFESKVRQHAGETVPAQGLFLDEVYYR"
     gene            complement(3183..3818)
                     /locus_tag="LLC22_002488"
     CDS             complement(3183..3818)
                     /locus_tag="LLC22_002488"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292320.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBK5435710.1"
                     /translation="MDFLRKFGFFFLLLGVLSDFLTPYVLGLYYPELDQMKSVISVFG
                     EVSSPVRKAFLIWSVVSGIFFILSLPALYAAFVSTSRVLATLVTAAIAFYGIGDCIFT
                     GLFSINTHESSWNVSTWVHNIGSGLGYSGFLLFPVLLFLIYRKNGQMDVSHLYLGLSV
                     ISLLFAAIYGLARIPSINSWPLLNKIGFCQRISFFFNYVPIAWLSILHLKQ"
     gene            complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="LLC22_002489"
     CDS             complement(3965..5206)
                     /gene="sstT"
                     /locus_tag="LLC22_002489"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine/threonine transporter SstT"
                     /protein_id="HBK5435711.1"
                     /translation="MLEKFLDMSLVQRIVVGILVGILFGIFFPTWTFISILGTLFVSC
                     LKAIAPILVFFLTMASIAKHKIGNKTFVKPILILYLVGTLLSALVAVIVSSIFTVPIT
                     LQETVSEKAPQSLESVLSTMLTNVTQNPVQSLIDANYLGVLFWAVLLGLAFRARSEST
                     KELVDQISIALSQVVQVIIAFAPIGILGLVYQSIATTGIAGLAEYLQLLLVLIGTMLF
                     VALVVYPFLTFLFIKENPYPLIFFCLKESALPAFFTRSSAANIPINMMLAERLKLTKE
                     SYSISIPLGATINMGGAAITISLMTLTAVHSLGIEAPFVLKVLLCILSALAACGASGV
                     AGGSLLLIPLACSLFGISNDVAMQIVGIGFIIGVIQDSMETALNSSSDLLFTAIGELG
                     ARKRSGEKIKLKDCLDGLSER"
     gene            5404..6400
                     /locus_tag="LLC22_002490"
                     /pseudo
     CDS             5404..6400
                     /locus_tag="LLC22_002490"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302657.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="LTA synthase family protein"
     gene            6416..8434
                     /locus_tag="LLC22_002491"
     CDS             6416..8434
                     /locus_tag="LLC22_002491"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302655.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sulfatase-like hydrolase/transferase"
                     /protein_id="HBK5435712.1"
                     /translation="MSLLVIFLFYIQKIRFIHRFIEYFAFDSIEQLTQRWKKRIHWLF
                     VHKSYFLVAAFFYCFTFVQIFVLEPKEGWKETIQVALKIFTQRQAPMILTIIIIMGFF
                     FLLLLISNRFWYALTATLIINLLLTISTVIKMEMREEPVFPSDLKMLTGLSELLSMVS
                     PVLLIVGGLILLLLLITSIIVQRRLQKQYSLKIHWKRRFISIAVLLGCFSGVFFINHK
                     NSPSFLLFNLFKVNKTFFNQQGAVKDNGPVIQFLNNIDIKIMEEPAGYSKEKINGIMK
                     KYNTKADEINQTRSDWLNNQTIVLNLSESFSDPARVPNLTVPTDPIPYIKSIITEGTG
                     GLMLSVGYGGGTANMEWEGLTGLSISNLSASLVTPYTQLVERQKISPNITDLFDEKIA
                     IHPFTAALYRRKQVFDKFGFDRFYYLDSPDKLTYTDKIEQSPRISDDSAYKETLKALQ
                     SNTETSQFIQLSTMQNHMPYDDYYSELNYTAEGTAVIPNRRKELQTYMQGLHYTDTAV
                     KKFIQEIDKIDKPITFVFYGDHLPAIYSGNDSKKYGLEQHQTDYFIYNNKYSREQAAT
                     LNKEVVAPNNFGAMALEHANIKVTPYYALLTEVSNHLPALTIDPTESLSNRFNGKQVF
                     VTEDSQIIQEKNLTEKQKEILEDYRLIQYDLVAGNQYSATWATQKIKD"
     gene            complement(8494..9186)
                     /locus_tag="LLC22_002492"
     CDS             complement(8494..9186)
                     /locus_tag="LLC22_002492"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBK5435713.1"
                     /translation="MGLAFLLAGCTNGNESKKESTKETAKATVATTTTTSTESKSTAA
                     STETADTSTSSESSKTTETTQTSTSSSSVEASSSSSESSEQVEQTLWNADKSAQLEAF
                     MTKWGQTMGQQYKSYTNQMSVDLYGLKVPQAILNGEWKMAIGGVPVSAEWSESGTGQA
                     DYQITAVYSDAETEPYLKKHVYLFGFQQNQPKVLVTQQNQGNPDNYLYFNETANNELK
                     NGFNQIVYGQAN"
BASE COUNT         2978 a         1706 c         1445 g         3080 t
ORIGIN      
        1 actaatcaga atcgtacaaa tatttaataa ccaaatatat agaacataac ttaatattaa
       61 gttatttgaa attccataaa aaacgactgc aggaattatt gtaagaaaag gataaaaata
      121 gttcagtcca tctccataat tgttaaatgt tgtatagttg attggccctt caaaaataga
      181 agataaccct ttgattcgtg aaagatgaaa agataaatca cctgttgtat aaatttcttg
      241 agcatttctc ataaaattta ctgaatataa agtactaagt aagataagaa ctactaaaag
      301 aaatgctttt ttacttattt tcatagattt gttgttctcc ttttttaatt ctattttcag
      361 tatactagaa ttgtcttttt ttaataagtt ttgcgttaaa tttttcatag cactagtatg
      421 atatactaga aaagaatcaa tttttattac ttttaaatag gagaaaaaaa tgaaaaaaaa
      481 caaaaaccaa ataatagata tcatttttat gttatttcta agttttgctt acgtcatccc
      541 tctattcatg tctatgggaa tctatcatag tgtcaatcag gatacttact ttcatttatc
      601 tcgaatcata ggactagata atgtatggag ttctccagta aacttcaata acttcgatca
      661 tcatggaaca atgatgaata ttttttatcc atggcttact ctttatccag cttttttatt
      721 ttataaaatg atgggaaatc ttgttttaag ttataatatc tactattttt ttatcacttt
      781 tttaacaatg gtcgtttctt atttttctat gaaacaaata aaaaacaatc gttatatttc
      841 gctgttattt tcgattattt atacattttc cgcctatcgt gccattgaca tattccatcg
      901 tgcttcattg ggagaagctg tcgctttaac atttttgcct ttgatactaa tggggtgtta
      961 cgaaatttat attagagatt accaaaaatg gtactggttg tctattggca tgacgctagt
     1021 agtgtatact catttacttt ctgtcgctat ggtttctgta tttattggag gaacgttgtt
     1081 tctttctttt tatttttggg accaaaaaat cgctagactc ttaagtcttt taaaagctac
     1141 cgtcctcacc ttttttttaa gtgcgggatt cttaattcct tttattcaac aatctagagc
     1201 acaagaattg aaagtcccac tgggaaaaga attaagtggt atggctccta gtgatatgct
     1261 gacacacatt ttaaataata actataacaa ctatactatt ggattattct tatttctcgg
     1321 attgattggt gcttttattt ttataaaaaa attaactgct gatgatttat ttattttctt
     1381 tcttggtgta tttgttcttt tttgttcaac caatttattt ccttggcaac tttttaacca
     1441 tacaccagtt aagagtctac aatttgtctg gcggttaaat ggtttttctt ctttatttat
     1501 agcctatacg atgagtatag tgatctatta tattttttct actaaaaata attcatggaa
     1561 aataatggtc tttacgtttc ttgcactaat attgcatctc tcaggagtaa gcaattctat
     1621 ccatgctaac aaagattcat taacacttat agcacctgaa gacgctgttg ctatagctga
     1681 aaattacaat catactgatt atgcaaacaa agagtcaatc tatcatcctg atatgattaa
     1741 taatgatcaa tatttactag gtaaccagga aataaatcca acaactcatt ttatgagtaa
     1801 caaacttaca attgaattag ataattcgaa taataaaaat actgtcttga cgacacctat
     1861 ttatcgttat aaagggcaag tggcttctat taatggcaaa ctagtacaaa caaaattatc
     1921 taagtttggc acaactgaat taactattcc tccaggtata aataaagtcg ttattactta
     1981 tcagtacaca aaactagcaa ttgcttcaag atatttatct atcgttactt tgattttatt
     2041 tttactttat cgatttactt tttctaaaca aaaacaaccg agaagagaag tacaacattc
     2101 tcactagatt tttatttaag aaagactttt tagctgtaca cataaacagg ctaaaaagtc
     2161 tttttttata tttctttaat ttgcttcata cattatttaa catcgatatt tatactgtga
     2221 aacatgcgtt tcatccatta tcaaagtatt tttatcgata ataaacttca tccaaaaaca
     2281 gaccttgtgc agggacggtt tctcctgcat gttgccgcac tttgctttca aatatttcat
     2341 cgattgtttc tatcggcatg gcacctgtgc cgatttctag taatgtcccc atgataatcc
     2401 gcaccatttt atataagaat ccgtctccga caaaagtaaa atgaagcatt tctccctttc
     2461 gttcgataga taattcatca atcgtacgca ctgtggattt ttttgatttt ttcaatgcag
     2521 aaaaaccaat gaaatcatgt gtacccacta atttttcgca agctgcattc agcttgtcca
     2581 tatccaactc ttgagggaaa taaaagctgt ggtttcgctc aaatgctgaa ggaatcacgt
     2641 tgttccaaac ataatagctg tattttttgc ccaccgcatt atatcttgaa tggaagcgct
     2701 caggcatttc ttcgattctt ttgatgacaa tatcccgcgg aaggtaacga ttcataaagt
     2761 cgatcatttc tgccagtcca atttctgtgt ttgttttaaa atttgctact tgtcctcgcg
     2821 catgggtgcc agcatctgtt cttcctgatc caataatttc tatctcttca tttgtcatct
     2881 gatgcaatac tttttcgatt tttccttgaa tggttttatc gtcatctcca agtctttgcc
     2941 atcctgaata tctttttccg tcatattcga ttgtcaactt gatgtttctc atattttagt
     3001 ggctcctctg tcttccattt ggtcttctct ctaccttttt aagattgtag cacaaaatat
     3061 agctcctttc ttctctaaaa cagaagctat acaagaaaac tgtggaaata tatatttcag
     3121 aaaaacaaaa aacagccacc ggatgaagta tccgctgact gttcaatttg acggctcaag
     3181 ttttactgtt tgagatgcaa gatactcaac caggcaatgg gcacataatt aaagaaaaaa
     3241 ctgattcttt ggcaaaaacc tattttattc agtaatggcc aagaatttat agaaggaatt
     3301 cttgccagtc cataaatcgc cgcaaaaagc aaactgatca cagacagtcc aaggtataag
     3361 tggcttacgt ccatttgccc attttttcga tagatcaaga aaagaagaac tggaaacaat
     3421 aaaaaaccac tgtaacctaa acctgatccg atattatgga cccatgtcga gacattccac
     3481 gaagattcat gggtattgat actgaacaaa cctgtaaaga tacaatcacc tataccatag
     3541 aacgcgatgg ctgctgtaac tagggtagct aacacacgag atgtacttac aaatgcagca
     3601 tacaatgcag gcaatgacag gatgaaaaag atccctgaaa ccacagacca aataagaaac
     3661 gcttttctta caggactgga aacctctcca aatacactga tcacgctctt catttgatct
     3721 aattcaggat aatacaatcc taatacgtac ggagtcaaaa aatcactcag cacgcctaat
     3781 aataaaaaga aaaaaccaaa tttacgtaaa aaatccatga tacgcctcca ataacaatta
     3841 cctatgcttt taattgttat tataaacgac tttatcttga tttaacagaa acctctattt
     3901 acacgaacat ctatataact cattaaaaac tcgaatcatt ttaaaaatac taaatatcta
     3961 acgttcaacg ttcacttaat ccatctaaac aatctttcaa tttgattttt tccccacttc
     4021 ttttacgcgc gcctagctct cctattgcag taaacaacag atcacttgac gaatttaagg
     4081 cagtttccat tgaatcctgg ataacaccga taataaatcc aataccgacg atttgcatcg
     4141 cgacatcatt agagatacca aacaaactac atgctaatgg aatcaataac agtgaaccgc
     4201 ccgcaacacc tgaagctcca caagcagcta aagcagacaa aatacataaa aggactttca
     4261 aaacaaaagg tgcttcaatc cctaaagaat gtacagcagt caacgtcatc aaggaaatgg
     4321 taatcgcggc accgcccata ttgatcgtag cacctaacgg gatcgatatg gaataagact
     4381 cttttgtcaa tttcaatctt tcagccaaca tcatgtttat cgggatattt gcggcagaac
     4441 ttcgggtaaa gaaagcggga agtgcgcttt ctttcaaaca aaagaaaatc aatggatagg
     4501 gattttcttt aataaacaaa aacgtgagga atgggtacac aactaatgcg acaaacagca
     4561 tcgtaccgat caaaacaagt aaaagctgca gatactctgc caatccagcg attccagtcg
     4621 tagcaattga ttgataaacc aatcctaaaa tccctatcgg agcaaatgca ataatcactt
     4681 gtacgacttg tgacaacgct atagatatct gatccaccaa ctcttttgtc gattctgaac
     4741 gtgctcgaaa agctagtccc aacaatacag cccagaataa gacgccaagg taattcgcat
     4801 caataagaga ttgaacagga ttttgtgtga cattcgtcaa catagtagat aaaacacttt
     4861 ccaaactttg cggtgctttt tcagatactg tttcttgtaa agtaatagga acagtaaaaa
     4921 ttgaacttac aataactgct acaagtgcag aaagcaatgt tcccactaaa tataagatca
     4981 aaataggctt cacgaatgtc ttattcccaa ttttatgctt ggcaattgac gccatcgtca
     5041 agaaaaaaac cagaataggt gcgattgcct tcaagcaact gacaaacaac gttcccaata
     5101 ttgaaataaa tgtccatgtg gggaaaaaga taccaaacaa tattccgact aaaataccaa
     5161 caacaatacg ttgaactaac gacatatcca aaaacttctc taacaaatga ccaccctttc
     5221 acaattttaa caatcattgt atcattttat gcaaagaaac taaaggtata attttctaaa
     5281 aattctaaca atacaaacaa ccatttcttg ctaattttgt actttttctg tctacacgtt
     5341 gttttttgag atattctaag ttaggatgtt attaatgggc aacttatcag gaaacgtttt
     5401 cttatgtttt tgtccaattt ttttgtgagg tgtttattct tgaaaaaaat aaagaaggag
     5461 agttatggct tcctgacaat ctttgtcgct tgtataatga tggttttaca gcgtatattg
     5521 atttcagcag tcactattcc tacatatgca acaaaccctg gtcgattcta catctataca
     5581 tttttacaaa cttccgttgt tattggtgca aatttgatcc cactttacat gggttaccaa
     5641 tatcaaaaaa tcgcccgttt aaaagtttta cattatttaa gtcgttttgc ctttatattc
     5701 ctaatagcca cactagtttg caatatcttt tttttacgta caagctggca gcttgaatat
     5761 tcgtgattat tggcttatcc taacacctat cagtcagaat tactttactt atgctgtttc
     5821 ttgtactttg cttttttgta gtattcctta tacagttgga tttttaaata aattatcgaa
     5881 aacaacaatt aaatatctac tattattttt aacaattgga ttagttggct gctctactct
     5941 atttaataaa gacccgtttg cattacagaa tggacagagt attttatgga ttttttattt
     6001 atttttaatg ggttatggtt tgaaagaatg gaactggaaa gaaaaggtcc gctataagct
     6061 tcctcaagta tttatcagct tgattgtttt attcggtttg attattttga tgacacaaat
     6121 ttcactcatc atcagaggaa atacagatac agcgctgagg ttttctaaac catattctct
     6181 cttcgcaatg tattatactt tctcttcgtt tttattttta gaaatgctat ctgataaatt
     6241 aggtataaaa ggaagaggaa attttcttgc tgtatttttg attgtcactc aagttatatg
     6301 taatttccct ttagtttctt atcgcgtatc tacatttatg aaacgtgaat ttccaaactc
     6361 agggaaggca tggctgataa atatcgggca gttttttatt tgctatttat tagcagtgtc
     6421 cctcctagtt atctttttat tttatataca aaaaatccgt ttcattcatc gtttcatcga
     6481 atacttcgct tttgattcga ttgaacaatt aactcagcgt tggaaaaaaa gaattcattg
     6541 gctttttgtt cataaaagtt attttttagt tgcagcattt ttttactgct ttaccttcgt
     6601 gcagattttc gttttagaac caaaagaagg ttggaaagaa actatccagg ttgccttaaa
     6661 aatatttact cagcgacaag cacccatgat cctgacaatc atcattatta tgggattttt
     6721 cttcttacta ttgttgattt ccaatcgttt ttggtacgcc ttgactgcta ccttgatcat
     6781 taacttactg ctcactattt cgacagtaat caaaatggaa atgcgggaag agcctgtctt
     6841 tccttcagat ttaaaaatgc tgaccggatt gtcagaacta ttatcgatgg ttagcccagt
     6901 cttattaatc gtgggcggat tgatccttct cctattattg attactagta ttattgtaca
     6961 acgtagacta caaaaacagt attccttgaa gattcattgg aaacgtcgat ttatcagtat
     7021 cgctgtatta ttaggatgtt tttcgggtgt ctttttcatt aatcacaaaa attcgccttc
     7081 tttcttgctg tttaatttat ttaaagtaaa caagactttc tttaaccagc aaggcgccgt
     7141 aaaagataac ggaccagtca ttcaattcct aaacaatatc gacattaaaa tcatggaaga
     7201 acctgctggc tattcgaaag aaaaaattaa tggaataatg aaaaagtaca acacaaaggc
     7261 agatgaaatc aaccaaacaa gaagtgactg gttaaacaat cagacgatcg ttctcaattt
     7321 aagtgaaagc ttcagtgatc ctgcacgtgt ccctaatctg acagtaccta cagaccctat
     7381 tccttacatc aaaagcatta taacagaagg aacaggagga ttgatgttat ccgtcggtta
     7441 tggtggcgga acagctaaca tggaatggga aggactgaca ggcttgagta tcagtaacct
     7501 gtctgcttcg ttagttacac cttataccca gctagtggag cgtcagaaaa taagtccaaa
     7561 tattaccgat ctattcgatg aaaaaatagc catccatcct tttacagctg ctctttatcg
     7621 cagaaaacaa gtgtttgata aatttggttt tgacaggttc tattatttag acagtccgga
     7681 taaattaact tatacggata aaatagaaca aagcccacgc atatcggatg attcagcata
     7741 caaagaaacc ttgaaagctt tacaaagcaa tacagaaacg tcacaattca tccaattatc
     7801 cactatgcaa aaccatatgc cttatgatga ttactatagt gaattgaact acactgctga
     7861 aggaactgct gtcattccta atagaagaaa agaattacaa acttatatgc aaggccttca
     7921 ctataccgat acagcagtaa aaaaattcat ccaagaaatc gacaaaatcg ataaaccgat
     7981 tacctttgtt ttttatggtg accatttacc cgcaatctat agtgggaatg attcgaaaaa
     8041 atatggatta gaacagcacc agacagatta tttcatttat aacaacaagt atagtcgtga
     8101 acaagcagct acgttaaata aagaagttgt tgctcctaat aactttggtg ctatggctct
     8161 tgagcatgcg aatatcaaag taactcctta ctatgcgttg ttgacagaag tatctaatca
     8221 tctacctgca ttaacaattg atcctacaga aagcttgtct aatcgtttta atggaaaaca
     8281 ggtctttgtt acagaggata gtcaaattat ccaagaaaaa aatttaactg agaaacaaaa
     8341 agaaattcta gaagattatc gtctgataca atatgatctt gttgcaggta accagtacag
     8401 tgcaacatgg gcgacacaaa aaataaaaga ctaacaaata aactgagcaa ggggttgtga
     8461 taaaagacat gtcacaaccc cttgtttatc tcattaattt gcttgtccat aaacgatttg
     8521 attaaagcca tttttcaatt cattattcgc tgtctcgttg aagtaaagat aattatcggg
     8581 attcccctga ttttgttgtg tcaccaatac ttttggctga ttttgctgaa acccgaatag
     8641 atagacgtgc tttttcagat atggttctgt ctctgcatcg gaatagacgg ctgtgatttg
     8701 atagtctgct tgacctgtcc cactttctga ccattctgca gaaacaggca ctccaccaat
     8761 agccatcttc cactccccgt tcaaaatagc ttgagggact ttaagaccat ataagtccac
     8821 actcatttga ttcgtataac ttttgtattg ttgtcccatt gtttggcccc atttggtcat
     8881 aaatgcctct aattgtgcgg atttgtctgc attccacagt gtttgttcaa cttgttcgct
     8941 gctttctgaa gaggaagatg aagcctctac agaagaactt gaagtagatg tttgagttgt
     9001 ttcagtcgtt ttggaagact ctgacgaagt agaggtatct gctgtttctg tacttgctgc
     9061 agttgacttg ctctctgtgc tagttgttgt agtagttgca actgttgctt tcgctgtttc
     9121 ttttgttgat tcttttttcg attcattccc gttggtacaa ccagctaaca aaaaagctag
     9181 accaattgtt actaaaatcc tttttttca
//
LOCUS       DAFBVQ010000082         8969 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.085, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000082 DAFBVQ010000000
VERSION     DAFBVQ010000082.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8969)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8969)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8969
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.085"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(57..350)
                     /locus_tag="LLC22_002493"
     CDS             complement(57..350)
                     /locus_tag="LLC22_002493"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303172.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis protein"
                     /protein_id="HBK5435714.1"
                     /translation="MKLTVTPKAQKWFDSEIDLPETYGIRFFGKVYGKTEVHDGFSIG
                     MSVEQPEHPVKKVEIDGTLFFIEEADEWFFKGYDLLVDYDPNLEEPTYHFKKQ"
     gene            complement(378..1043)
                     /locus_tag="LLC22_002494"
     CDS             complement(378..1043)
                     /locus_tag="LLC22_002494"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624078.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TrkA family potassium uptake protein"
                     /protein_id="HBK5435715.1"
                     /translation="MKQNFAIVGLGRFGGSICRTLIEAGQEVLAIDSNEDRVNEYMNI
                     ATHAVVANAQDEMTLRSLGIRNFDHVIVAIGEDIQASILVTLMVKEMGVPNILAKAQN
                     EYHARVLEKIGADRVVHPERDMGIRIAHNLVSKNILDYLELSDKYSLAEIRVSNPKFF
                     NKTLAELNFRQRFDLTVVAIRRVDQTVIASPAADEYVRENDNLLVIGETGDVDILDDK
                     MNQ"
     gene            complement(1183..1815)
                     /locus_tag="LLC22_002495"
     CDS             complement(1183..1815)
                     /locus_tag="LLC22_002495"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016624081.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5435716.1"
                     /translation="MIKVLLVDDHEMVRLGVSSYLSIQEDIEVIGEAENGRQGYEKAM
                     TLRPDVILMDLVMEEMDGIESTKAILKDWPEAKIIIVTSFIDDEKVYPAIEAGAAGYL
                     LKTSTAHEIADAIRATQRGERVLEPEVTTKMMEKMSRRNEPVLHEELTNRENEILMLI
                     SEGKSNQEIADELFITLKTVKTHVSNILAKLEVEDRTQAAIYAFKHGLVK"
     gene            complement(1822..2889)
                     /locus_tag="LLC22_002496"
     CDS             complement(1822..2889)
                     /locus_tag="LLC22_002496"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sensor histidine kinase"
                     /protein_id="HBK5435717.1"
                     /translation="MMGKISRAMLAVYSGIAAFLIILFSLFTYFYASNQSHWWGELLR
                     ARLLYVPLIFHLLAISLGVGLIVFLLLSLIQKTKYGKIEEKLRALSSGNYESKLLLLP
                     IPSASDDLYIKDIDKEITKIKEKMIEVSSELQIVTSRPQYVDGQTKEEILELERHRLA
                     RELHDSVSQQLFAAMMMMSALTEQAEKSETPEMFRKQLKMVAEIINASQSEMRALLLH
                     LRPVNLEEKSLKQGIEQLLKELQNKIQISLKWDVEDVKLSSSIEDHLFRIVQELLSNT
                     LRHAKANELEVYLHKIDNNLLLRIIDDGTGFNMNETKTGSYGLNNIKERVAGIGGTVK
                     IISFKGQGTSVEIKVPLMKEA"
     gene            complement(2886..3617)
                     /locus_tag="LLC22_002497"
     CDS             complement(2886..3617)
                     /locus_tag="LLC22_002497"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335558.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell wall-active antibiotics response protein"
                     /protein_id="HBK5435718.1"
                     /translation="MNSSWRFFVVVEALLLLFAVWQIVNNTGLLLLVIFGIFNIYLAM
                     RKHPRTKFQNFQLILGSLVIFFSLVNSPALWMMAVFAVLFIGLKGVEISGIDLTKNAF
                     WRKKQIMMIQTEQLKTHNNERKRQQLFGNQRIGNDVYEWDDINIAVISGDTIIDLGNT
                     LLPKDDNIVIVRKGIGRTRILVPLGVAIRLEHATLVGNVLFEEEQFSLKNEQIKIYSS
                     DYDENPRRLKIITNTLIGDVEVIRI"
     gene            complement(3786..4265)
                     /gene="greA"
                     /locus_tag="LLC22_002498"
     CDS             complement(3786..4265)
                     /gene="greA"
                     /locus_tag="LLC22_002498"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016172390.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcription elongation factor GreA"
                     /protein_id="HBK5435719.1"
                     /translation="MVEKVYPMTLEGKEKLEKELEELKTVKRGEIIERIKIARGFGDL
                     SENSEYESAKDEQAFVEGRITTIENMIRFAQIIDNDGVDADEVSIGKTVTFIELPDGE
                     EEEYTIVGSAEADPFSGKISNDSPIAQALIGKRKNDEVTIATPGGDMLVKIVKVEQA"
     gene            complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="LLC22_002499"
     CDS             complement(4401..5576)
                     /gene="mltG"
                     /locus_tag="LLC22_002499"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="endolytic transglycosylase MltG"
                     /protein_id="HBK5435720.1"
                     /translation="MSGNKQHPSKDKKEASKAATADIIDKRRNLRKKEDKIVRKIILV
                     IALTLLIIGGFLGFTVYRYVDSGLKPLDKSDDQLVQVEIPSGSSNKQIGEILEKDNII
                     KSGIVFNYYTKFKNLTGFQAGYYQLAPNMTLDEIGKQLQEGGTSEPTKVADGKIAIPE
                     GYDIDQIAERVAKVTGKDKKEFLDLVNDETFFNELHQKFPELLESASKAENTKYRLEG
                     YLFPATYDYYTSTSLKDLVIEMVNKTNTVMQNYYSAIKQKNLTVQEVLTLASLVEKEG
                     VKENDRKNIAQVFFNRIKANMPLQSDISVLYALGEHKELVTYEDTAVDSPYNLYTNTG
                     YGPGPFDNPSEEAIKAVLEPAENDYYYFVADTSTGNVYFAKTYEEHMELVEKYVNNS"
     gene            5780..6949
                     /locus_tag="LLC22_002500"
     CDS             5780..6949
                     /locus_tag="LLC22_002500"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="beta-lactamase family protein"
                     /protein_id="HBK5435721.1"
                     /translation="MKKGKHAKKRKYSFLMIVVVLFSLSAFSTGTILGWQFYNNEHSQ
                     IVAHAQSAQKKLILTTNEQQLVEKIDQLLRKNDYIGSIYVKKNNRIIMEKGYGYANKL
                     TQQPNDPSLYYQIGSVQKALTTLLILKQVERGHLSLDTKLAQFYPQIAGSQQITIRDL
                     LYMRSGLHRTASPTIPMTDEEVVQFAIQHLKFTDYQTSHYDSLNFTILTGILIKLTNQ
                     PYEKLLTDDIIEPLGLQHTKFYDQVKNSSNHALSYQMSKEDDYFKPLTESETEIHNEL
                     GTGNISMSVYDLNTLFTQVLSGKLVSKDLLFSLWRENANGHPYSGGVYSGDNYILSQG
                     NIDSFDTSAIFSKDSQDAIIMESNIKADKTIKLPTADLRNQIYDLMEGTTKLANS"
     gene            complement(7216..8850)
                     /locus_tag="LLC22_002501"
     CDS             complement(7216..8850)
                     /locus_tag="LLC22_002501"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349576.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435722.1"
                     /translation="MRWYMNLKKIFSVKIFIVYAFVSLLYLFPAFKNMEIFGFYDTAF
                     HINRALSLESIFSSPINFETFRSYGMQVNNFYPWLTLYPLFLLIKFTNLAIGYNLFLY
                     IVTLITLFICHYVMYEITKKHVTSSFFAIIYTTSSFRSVEIFLRGAMGELLAMSILPL
                     ILLGFIKLYDSKKESWVMLAISMTLLIYTHVLSVAMTMVMIIIALIIQFYRKKKIEIF
                     LIIKLIKAAIVTLLLSLAFIGPMIEQTLYQDLNRPYVDILQKRAIYLGKEFLIGSIDS
                     ELLSFGIGLTLLICLIILTFNFKKLGILSKITYIMGIISILLCTKIFPWFALQNTPLN
                     IIQAPWRFMIFSTLFISFSVSLFISPQLEKFSYTRRRNFILLLILAISILNYSSVVNM
                     VKEMNFQGTYSNEQMENKLEEFENFDYVPIGYKKDQLLLKNHQVTEDGQVIYSSFSPN
                     KDEITFTLKSSKGKTIVLPVFRYKGLTVTVNSKNATVLKQGGPFVTVKSESGINKVTI
                     RYSYTFFSKISLFISIITLIVLLFYCIKLKIRTSHE"
BASE COUNT         2856 a         1701 c         1333 g         3079 t
ORIGIN      
        1 aatattttca aaagaaaaaa gagaaggtga caaaaattgt gtcaccctct ctttttttat
       61 tgttttttaa agtgataggt tggctcctcc aggttgggat cataatcaac aagtaaatca
      121 tatcctttaa agaaccattc atctgcttcc tcgataaaaa aaagtgtccc atcaatttcc
      181 actttcttta caggatgttc tggctgttca actgacattc caatcgaaaa accatcatga
      241 acctctgttt tgccgtagac ttttccaaaa aaacgtattc cgtaagtttc tggcagatca
      301 atttctgagt caaaccactt ttgtgctttt ggcgttaccg ttaatttcat cccaacaacc
      361 tactttctct tttctttcta ttgattcatc ttatcgtcta gaatatccac atcgcctgtc
      421 tctccaataa ccagtagatt atcattttca cgaacatatt catctgctgc aggagaagcg
      481 ataaccgttt gatctactct tcgtatggcg actactgtta agtcaaaacg ttgcctgaaa
      541 tttaattcag ctaatgtttt gttgaaaaat ttaggattgg agactcggat ttctgctaaa
      601 gaatatttat ctgacaactc taggtaatct aaaatattct ttgacactaa attatgcgca
      661 atccttattc ccatgtctcg ctcgggatgg acgacgcgat cagctccgat cttttcaagt
      721 actctggcat gatactcatt ttgggctttt gctaaaatat ttggtacgcc catttccttt
      781 accatcagag taactaagat actggcttga atatcttctc caatagcgac aattacatga
      841 tcgaaatttc ttatgcctaa tgatcgaagt gtcatttcat cctgtgcatt tgccacaaca
      901 gcatgagtgg ctatattcat atattcattg acccgatctt cattactatc aatagccagt
      961 acttcttgac cagcttcgat cagtgttcgg cagatacttc cgccaaatcg tccaagacct
     1021 acaattgcaa aattttgttt caccgttttc ctcctttagt atcttctttt ctcagtataa
     1081 caaagccttt acaaaaacaa aagcaagcat cattattgta aaaaagccaa gaaaaataat
     1141 agttattttc tcagcttttg attatcctct ttatcatcgt ttttatttca ccaaaccatg
     1201 tttgaatgca tagatagcgg cttgtgtacg gtcttccact tctagcttag ccaatatatt
     1261 ggaaacatgt gtttttactg ttttcagtgt aataaacaat tcgtccgcta tttcctgatt
     1321 actttttcct tcagaaatca gcattaaaat ttcattttcc cgattcgtta gttcttcatg
     1381 taatacaggc tcatttcgcc gactcatttt ttccatcatt tttgttgtca cttctggttc
     1441 taatactcgc tcgccacgtt gcgttgccct tatagcatca gcaatttcat gtgcggtaga
     1501 ggtcttcaac aaataccctg ctgcacctgc ttcaatggca ggataaactt tttcgtcatc
     1561 aataaaactg gttacgataa tgattttagc ttctggccaa tcttttaaga ttgcttttgt
     1621 tgattcgata ccatccattt cttccatgac taagtccatt aaaatgacgt ccggtcgaag
     1681 tgtcatcgcc ttctcatagc cttgtcgtcc attttcagct tctccaatta cttcaatgtc
     1741 ttcttgaata gataaataag aagagacgcc taagcgcacc atttcatggt catctactaa
     1801 taaaactttt atcatcctta tctatgcctc cttcatcaaa gggaccttga tttctacact
     1861 tgtaccttga cctttaaaac taatgatttt tactgttcca ccaataccag ctactcgttc
     1921 tttgatattg ttcaatccat aacttcccgt tttcgtttca ttcatattaa accctgttcc
     1981 gtcgtcaata atacgtaaca aaagattatt gtctattttg tgcaaatata cctctaattc
     2041 attggcttta gcatgtctta atgtatttga taacaattct tgaacgattc ggaacaagtg
     2101 atcctcaatg gaactagata gttttacatc ttctacatcc catttcagcg aaatctggat
     2161 tttattttgc aattccttca ataactgctc gataccttgc tttaaacttt tctcttctaa
     2221 attgactgga cgtagatgaa gaagcagcgc acgcatctca gactgggaag cgttgatgat
     2281 ctctgctacc attttcaact gcttgcgaaa catttctggt gtctcgcttt tttctgcttg
     2341 ctccgtcaat gccgacatca tcatcattgc tgcaaacaat tgttgcgaaa ctgaatcatg
     2401 cagctcacgg gctaatcgat gtctttctaa ttctaaaatt tcttctttgg tttgtccatc
     2461 tacatattgg ggacggctcg ttacaatttg taattcacta gatacttcaa tcattttttc
     2521 ttttatctta gtgatttcct tatcaatatc tttgatgtat aaatcgtccg atgcacttgg
     2581 gatcggaaga agcaacaatt tggattcata attgccagaa gaaagtgcac gcagcttttc
     2641 ttcgattttc ccgtattttg tcttttgaat aagtgataat aatagaaaga caattaatcc
     2701 tacacctaag gaaatggcta acaaatggaa gataagcgga acatataata aacgtgcacg
     2761 cagtaattct ccccaccaat gactttgatt gctggcataa aaataagtga aaagtgaaaa
     2821 tagaataata aggaaagccg caatccccga ataaacagct agcatcgctc tggatatttt
     2881 tcccatcata ttcgtatcac ctcgacatct ccaatcaagg tattagtaat aatcttcaat
     2941 ctacgagggt tttcatcata atcactgctg tagattttga tttgttcatt tttcaaagaa
     3001 aattgctctt cttcaaacaa gacatttcct actaatgtcg catgctctaa tcggatggct
     3061 acgcccaaag gtactaagat ccgtgttctg cctatccctt ttcttacaat cacaatatta
     3121 tcatcttttg gcaaaagcgt attgcccaaa tctatgatag tatcaccaga aatgacggcg
     3181 atgttgatat cgtcccattc atagacgtcg tttccaatac gttggttacc gaataattgc
     3241 tgtcttttcc gctcattatt atgtgttttt aattgctctg tttggatcat catgatctgt
     3301 ttctttcgcc aaaaagcatt tttggttaaa tctatccctg aaatctctac acctttcaga
     3361 ccaataaata aaacggcaaa tacagccatc atccataaag caggactgtt gactaagcta
     3421 aaaaaaatga ccaaacttcc taatatcaat tgaaaatttt gaaatttagt acgaggatgt
     3481 ttgcgcatag ctagatatat attgaaaata ccgaatatca ctaaaagcaa aagtccagta
     3541 ttgtttacga tttgccaaac agcaaataac agcagtagtg cttcaactac cacaaaaaaa
     3601 cgccaagaac tattcatcgc tctttctccc tcctgacaca ttctcatttc atcataccta
     3661 tttttttaac tgttggctat aggactttag atgtaagatc gtttgttgaa atctaaaata
     3721 cacaaagaga aaaagatcta gagtgtatca tcagtaagat gaactctcta gatctttcag
     3781 tcagactacg cttgttctac tttgacgatt ttaactaaca tatcgccacc tggagtagca
     3841 atagttactt catcattttt acgtttgcca atcaatgctt gcgcaatagg agaatcattg
     3901 gaaattttgc cagaaaacgg atctgcttca gcgcttccga caatcgtgta ctcttcttct
     3961 tctccatctg gtagttcgat gaatgtaact gttttaccaa ttgatacctc atctgcatct
     4021 acaccgtcgt tatcgatgat ttgagcaaaa cgaatcatat tttcaattgt tgtgattctt
     4081 ccttcaacaa atgcttgttc atctttcgct gattcatatt cagagttttc ggaaagatct
     4141 ccgaaaccgc gggcaatttt gattcgttca atgatttctc cgcgtttgac tgtttttagt
     4201 tcttctaatt ctttttctaa tttttcttta ccttctagag tcattggata aactttctct
     4261 accatgtgta acgtctcctt ttttcgataa aataccgcaa aaggtaatct tttgaggaat
     4321 atagtccaaa aaagattacc acgcttttct tcaaatgtaa atgtttttct aaaaatgatc
     4381 aatgtctaga gcctgttttt ctaagaatta tttacatatt tttccactaa ttccatatgt
     4441 tcttcataag ttttagcgaa ataaacattt ccagtgctcg tatctgctac gaaataataa
     4501 tagtcatttt ctgctggttc taatactgcc ttgattgcct cttcgcttgg attgtcaaaa
     4561 ggtccaggtc catagccggt attggtatac aaattatatg gtgaatctac agctgtatct
     4621 tcatacgtca ctaattcttt gtgttcacct aatgcgtata aaacagagat atctgactga
     4681 agtggcatat ttgctttgat tcggttaaag aagacttgtg caatgttttt acgatcattt
     4741 tcttttacgc cttctttttc aactagagaa gctagagtta aaacttcttg tacagtcaaa
     4801 tttttctgct tgatagctga ataatagttt tgcatgaccg tattcgtctt gttcaccatt
     4861 tcaatcacta gatccttaag cgaagtactc gtgtaataat catatgtggc tgggaataag
     4921 taaccttcca aacggtattt tgtgttctca gctttagatg cactttccaa cagttctggg
     4981 aatttttggt gcaactcgtt aaagaaagtc tcatcattca ctaaatctaa aaattctttc
     5041 ttgtctttac cagttacctt cgctacccgt tcagcaatct gatcgatatc gtacccttct
     5101 ggaatggcaa ttttcccatc tgcaactttt gttggctcag aagtaccgcc ttcttgcaac
     5161 tgtttgccaa tctcgtcaag agtcatatta ggcgctaact gataatagcc agcttgaaag
     5221 ccagttaaat ttttaaattt tgtataataa ttgaaaacaa tcccgctttt aataatattg
     5281 tccttctcca aaatctcacc aatctgcttg ttagaagagc cactcgggat ctcgacttgg
     5341 actaattggt catctgattt atctaaaggc ttcaacccgc tatctacata acgatacacg
     5401 gtaaatccaa gaaatccgcc aataatcaat aatgtaagag caatcactaa aatgatcttc
     5461 ctcacaatct tatcttcttt tttacgcaga tttctccgct tgtcgattat atctgctgta
     5521 gctgccttac tggcttcttt tttatcttta cttgggtgtt gtttgtttcc tgacaaaaca
     5581 actcctcctt actatcaagt tcgtaacttt attcattata catgatattt gaattggcgt
     5641 gaatgatttt atttaaatat tctatcaaaa atgtaagtag taaatccatt actataagat
     5701 taaaataaat gttatcaaga tacaagctat tttagcttta ttctttctgt aaaaaagaaa
     5761 ggagactaaa taaactatta tgaaaaaagg aaaacatgct aaaaaaagaa aatattcatt
     5821 tttaatgatc gttgtcgtgt tgtttagcct tagtgcgttc tctacaggaa ctattcttgg
     5881 atggcaattt tacaataatg aacactctca gatagttgcc catgctcaat cagctcaaaa
     5941 aaagttgata ctgactacca atgaacaaca gctcgttgaa aaaatcgatc aactattaag
     6001 aaaaaatgat tatattggct caatttacgt aaagaaaaat aatcgcatca tcatggaaaa
     6061 aggctatggc tatgcgaata aactcacgca acaaccaaat gatccttctc tttattatca
     6121 gattggttcg gttcaaaaag cattgactac tcttttgatt ttaaaacaag tcgagcgtgg
     6181 gcacctttct ttagatacta agctggctca attctatcca caaattgctg gcagccagca
     6241 aattactatc cgtgacttgc tgtatatgcg ctcaggcttg caccgaactg cttctccaac
     6301 cataccgatg actgatgaag aagtcgttca atttgcgatt cagcacttaa aatttacaga
     6361 ttatcagacc tctcattatg attcattgaa ctttaccata ttgactggaa ttttgatcaa
     6421 attaacaaat caaccgtatg aaaaattatt gaccgatgat atcatcgaac ctttaggatt
     6481 acagcataca aaattttatg accaagtcaa aaattcatcc aatcatgcac tatcctatca
     6541 aatgtctaaa gaggatgatt actttaaacc actgacagaa tctgaaacag agatccataa
     6601 cgaattaggg actggtaata tcagtatgtc cgtctatgat ttaaatacgc tgtttacaca
     6661 agttttatct ggaaaactag tttccaaaga cttactcttc tcattatggc gtgaaaatgc
     6721 gaatggacat ccatatagtg gtggggtata tagcggagat aattatatcc tgtcgcaagg
     6781 aaatatcgac tcttttgata catctgctat atttagcaaa gattcacagg atgctatcat
     6841 catggaaagc aatataaaag ctgacaaaac tatcaaactg cctactgctg atctaagaaa
     6901 ccaaatctat gacctgatgg aaggaactac taagttggca aatagctgat atgatgaaaa
     6961 gatagcaaat actacttctt tgaatagcat ttgcttaaaa aaagtactcg actaaacgta
     7021 ggaaagagtg tgggacaaat ctaaaaatca atttttgcta cagactttaa ttccaaataa
     7081 acagaacaga aagaggtgtt cttctttctg ttctgtccaa attattctaa gatttctctt
     7141 taccaacatt atttgacaaa gggcctatta aatctaaaat agtatcttta gattgctaaa
     7201 atatgtgcta gcaaatcatt catggcttgt tcttattttt aattttatgc aataaaaaag
     7261 aagaacaatt agcgtgatta tagaaataaa taatgagatt ttagaaaaaa atgtgtatga
     7321 atacctgatt gttactttat ttattccact ttcacttttt actgtaacaa aaggacctcc
     7381 ttgttttagt actgtagcat tttttgaatt aacagtaacc gttaatcctt tataccggaa
     7441 tacaggtaaa actattgttt tgccttttga agatttaagc gtaaatgtaa tttcatcttt
     7501 atttggagaa aagctactat aaataacttg accatcttct gtaacttgat ggtttttcaa
     7561 aagcaattga tcttttttat agcctatagg tacataatca aaattctcaa attcttcaag
     7621 tttattttcc atttgttcat tagaataagt tccttgaaaa ttcatttctt tcaccatgtt
     7681 aactactgat gaataattta aaattgaaat agctaatatt aataatagta taaaatttct
     7741 tctccttgta taagaaaatt tttccaactg tggagaaata aatagagata ctgaaaaaga
     7801 tatgaacaat gttgaaaata tcataaaacg ccaaggagct tgaataatat ttaaaggagt
     7861 attttgtaag gcaaaccatg gaaatatttt tgtacaaagt agaatagata ttatacccat
     7921 tatataagtg attttagata agattcctaa ttttttaaag ttaaatgtta gtataattaa
     7981 acaaataagc aaagttaagc caataccaaa tgatagtaat tctgaatcta tacttccaat
     8041 caaaaactct ttacccagat aaattgctct tttttgtaat atatccacat aaggtctatt
     8101 cagatcttga tacaatgtct gctcaatcat aggacctata aacgctagtg aaagaagtaa
     8161 agtaactata gcagctttta ttaatttaat aattaagaag atttctattt tctttttccg
     8221 ataaaattga ataattaaag caattataat cattaccata gtcatagcta cagaaagaac
     8281 atgagtgtaa attaataaag tcatgctaat cgccaacata acccaagatt ctttttttga
     8341 gtcgtaaagc tttataaacc cgagtaaaat aagaggaagt attgacattg cgagtaattc
     8401 ccccattgcc cctcgaagaa atatttctac actcctaaaa gaagatgttg tatatataat
     8461 agcgaaaaag gagctagtaa catgtttttt ggtaatttca tacattacat aatgacatat
     8521 aaatagagta atgagcgtaa caatataaag aaaaaggtta tagcctattg ctaaattagt
     8581 aaacttgatc aataaaaata aaggatatag agttaaccat gggtaaaaat tatttacttg
     8641 catgccatat gatctaaacg tttcaaaatt aataggggag ctaaaaatag attctaaact
     8701 taacgcacga ttaatgtgaa atgccgtatc ataaaagcca aatatttcca tgtttttaaa
     8761 tgctggaaat aaatataata aactaacaaa tgcataaact ataaatattt ttacagaaaa
     8821 aatttttttc aaattcatat accacctcat gtttttttat attacatata gtatcattta
     8881 tttttttaaa acactagatt agtcactata taaaatgtga ttaattttat tattaataaa
     8941 atatttttta tattacaaaa gtagtgttt
//
LOCUS       DAFBVQ010000083         8873 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.086, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000083 DAFBVQ010000000
VERSION     DAFBVQ010000083.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8873)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8873)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8873
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.086"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            586..1740
                     /locus_tag="LLC22_002502"
     CDS             586..1740
                     /locus_tag="LLC22_002502"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348970.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase C47"
                     /protein_id="HBK5435723.1"
                     /translation="MIILKPKKKIYLGLLFSLMIGIFSIGITNTYASENSNFNINSQP
                     IEEQAINFAKTDFEHSITSILLMENNTETDINYTLGSPFKMLDGENTANSSIFFPVFS
                     DADNTIKYIYTVKKNTNGEYSGSISQFLAKELQNLVDSNITDTTLFFQDNSIYYSDNG
                     QIKLLWKSPLSTEKNGVSSFTEKNDLISVNIKNKIKNFSKKQNFPAVKRVKSVSSGDN
                     FIMINWRIAETQTSFPWCAAYVEAAILCNKTDVHATSARAIMHYTYPNLNNSQIESKS
                     LNQDQIIKYANYCGVYPKKVARILNLSEVQTQLRKGNAIYMGTAGYGNYSNSRHALAL
                     FGWVNQGGYQTYYVWNPWYNYPTVISANAGPVTIPVPGGGFTWDNTITNW"
     gene            1734..2156
                     /locus_tag="LLC22_002503"
     CDS             1734..2156
                     /locus_tag="LLC22_002503"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348709.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435724.1"
                     /translation="MVNKPIALVMGLVLVLFLTSCSKKQEIQKTDLIPFLGTWQTKDH
                     SERLVITNLNTSKNIEQYTILVKENNHKIQIIDKNLNINEQVFIYKATNNLLTLRSNK
                     KQLDYTFSLDSPKKLVFILTTNDGTEGTAKPIEFFKAD"
     gene            2458..2838
                     /locus_tag="LLC22_002504"
     CDS             2458..2838
                     /locus_tag="LLC22_002504"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBK5435725.1"
                     /translation="MSEQNQNLASDHSKKYTYRSKPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVAPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            2820..3734
                     /locus_tag="LLC22_002505"
     CDS             2820..3734
                     /locus_tag="LLC22_002505"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBK5435726.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATIKTGINCDVDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQTAIYTHTDKDHIHN
                     HIVINSVNLETGKKFQAHGQAFLNKCYDLNDEICLAHNLPITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRIAIDQTMKNKKTRTYDQFCNSLKTLGIHCFNRGKNFTYELIHKKK
                     KVRSNRLGKDYEKETILHELDRRERTYNQQRTNELRRARASIRETAEEVRREQRTLTP
                     EQPEIRPARRNHEQHVERGTDHQQELSL"
     gene            3974..4663
                     /locus_tag="LLC22_002506"
     CDS             3974..4663
                     /locus_tag="LLC22_002506"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435727.1"
                     /translation="MAFYLPYLLIFVSISGSIWLIYKIFQTRYSLKGSKIRFKRFFFL
                     GCIFSLIIVSSGLFGVLEGNKRVSRSILLGNVTQKYESARDKKKKEQALAQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYVKDTKV
                     EEACSDLFGDTIPFSTSEQERKERQQSVTYERYEILLQQAINIQNLTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(4783..4869)
                     /locus_tag="LLC22_002507"
     CDS             complement(4783..4869)
                     /locus_tag="LLC22_002507"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBK5435728.1"
                     /translation="MFELFICPLLVGVCISVFSYWLNNRNKK"
     gene            5515..6447
                     /locus_tag="LLC22_002508"
     CDS             5515..6447
                     /locus_tag="LLC22_002508"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
                     /protein_id="HBK5435729.1"
                     /translation="MANEIVKYEPELNTIPLRKFTPIEMNLFFSIVSRMRDKGNQKIR
                     FYFSQLKDLSAYKQTAGEVFIKDLARTYDHLMDLRFGRKSNGGLTIERFTMFTDFEIH
                     GEVDNPYVDIKVHEKALPLLNNLESWVRFSLTEFRDLNSSYAKTMFRLLKQYRTQGWA
                     EFSKEDFLELLDIPKSYRQTNINQFVLKPIKEELTPLFKGLTIRKKYGKGRGKPVIGY
                     RFTWKAEINHADDFSKGKQEDLRIKLFNIEHNGELTQKEKWRAKDRILNLPLGTHEAD
                     FKKQQQTEKEEAEKQSISNELKQDLLENLQNLFD"
     gene            6464..6934
                     /locus_tag="LLC22_002509"
     CDS             6464..6934
                     /locus_tag="LLC22_002509"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302544.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBK5435730.1"
                     /translation="MIDKTIKELAEEFHVSKQAIRKRLSADFRENYVQTVTRNGVKTL
                     VVSYKGYLLLKQHFLGSNTTGNQVETVASNDENSIIVFLHEQLQEKDTQIKQMQKLLD
                     QQQQLTLQANQQIEKLQEQLQLAYTEEPEEEELTSVNKENNNAITTEKKWWKFW"
     gene            7018..7335
                     /locus_tag="LLC22_002510"
     CDS             7018..7335
                     /locus_tag="LLC22_002510"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5435731.1"
                     /translation="MTISKVIKQKRIEKQLTQEDLAEMLLVSKKTISNWENGRTIPDT
                     ENLIQFAKLFDLSLDNILLGEEKIMVKNYGKKSYKNTNTIISFCNFFKFSFHLNSVRI
                     LLF"
     gene            7625..8806
                     /locus_tag="LLC22_002511"
     CDS             7625..8806
                     /locus_tag="LLC22_002511"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313302.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FtsW/RodA/SpoVE family cell cycle protein"
                     /protein_id="HBK5435732.1"
                     /translation="MKNNRIYKNQLNYGLLLPVFLLCIIGLLSLYVALYHDSYTNSKI
                     TKELIKQVLWYSIGFTSAITIYFFNPKILWKLTPIFYGLCIIMLLLLLKFYNPQLAVL
                     TGAKNWFYIAGFSFQPTELVKIGYTLMLAKITVNYQQKSITSNTKDDWIYLLKTFIAT
                     LPIGILLFFQNDLGTMLVFIVIYIFILFTSNINIKIIAPIIAIGVVLSLIFLYLVISD
                     TGRDFLLKIGFHDYQFKRIDSWLNPFLDPNGSSYQLANSLIAIGSGGLLGTGFNVSNI
                     HVPVRESDMIFSVIGENFGFIGSCLVIFLYFYLIYQMYKTCFKSNNLFFTYIGIGIVA
                     MIFFHVFENIGASIGLLPLTGIPLPYISQGGSAILSNFLGLGFMLCCSRYTNEKKGTQ
                     K"
BASE COUNT         3296 a         1448 c         1465 g         2664 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaattcaaat tattacaaca gtcctaacga agaattgttt gtaaaacaaa cggataaata
      181 ataaaaaaga ctgctctttc gagcagccag ttaaaaaata atgagtgttt attcttgaaa
      241 aagcaacgcg cttatgaagc gctaccaaaa atttatcata ttttatgaaa aataacaccc
      301 cagtaaaaaa tgactggtaa aaattcacaa agaaacggaa agaagcaact gcagaaaatc
      361 aagccttaaa aagagctttt gacctagacc aatgaaaaat cacaaagtga gcccctgtat
      421 cccttggtag agaggctact tggcatagtc gacattatgt taactaacgc tataaataac
      481 gattatgttc ccaaaacaat attttatgaa ctataacaaa aatttgttat cgcatattgt
      541 atattttaat tataggtgta taccacttaa atttaacaca aaggcgtgat tattttgaaa
      601 cccaaaaaga aaatttatct aggtctcctc ttttccttga tgattggaat ttttagtata
      661 ggaattacaa atacctatgc ttcagaaaat tctaatttca atatcaactc ccaaccaatt
      721 gaagaacaag caattaattt tgcgaaaact gattttgaac actccataac ttcaattctt
      781 ttaatggaaa ataacaccga aactgatatt aactatactc ttggttcgcc atttaaaatg
      841 ctcgatggag aaaatacggc aaatagttct attttctttc cagtattttc agacgctgat
      901 aatacgatta aatatattta taccgtcaaa aaaaatacaa atggagaata ttcaggaagt
      961 atttcacaat ttttagcaaa agaacttcaa aatctagtag atagtaatat aacagataca
     1021 accttatttt ttcaagataa tagcatttat tattccgata atggacaaat taaactactt
     1081 tggaaatcac ctttaagtac agaaaaaaat ggtgtttctt cctttacaga aaaaaatgat
     1141 cttatatccg taaatataaa aaataaaatt aaaaatttct ctaaaaaaca aaattttcct
     1201 gcggttaaac gtgtaaaaag tgtctcctcc ggagataact ttattatgat taattggcgt
     1261 atagcagaaa cccaaacaag ttttccgtgg tgtgctgctt acgtagaagc tgctatctta
     1321 tgtaacaaaa cagatgtaca tgctacttca gctagagcca ttatgcatta tacctatcct
     1381 aatttaaaca acagtcaaat tgaatcaaaa agtcttaatc aagatcaaat aataaaatat
     1441 gcaaattact gtggtgttta tcctaaaaaa gtagcacgaa tactaaacct ttcagaggtc
     1501 caaacacaac taagaaaagg aaatgccatt tatatgggaa ctgctggtta tggaaattat
     1561 agtaacagcc gtcatgcact tgcattattt gggtgggtca atcaaggtgg ttatcaaact
     1621 tactatgtgt ggaatccttg gtataactac ccaactgtaa taagtgcaaa tgcaggacca
     1681 gttacaattc ctgtacctgg aggtggtttt acttgggaca ataccattac aaattggtaa
     1741 ataaacccat tgctttagtt atgggtctag tgttagttct tttcttaact agttgttcaa
     1801 aaaaacaaga aatacaaaag actgatctga ttccttttct aggaacttgg caaactaaag
     1861 atcattcaga acgtctagta atcactaatt taaatacttc aaaaaatata gaacaatata
     1921 ccatcttagt aaaagagaac aatcataaaa ttcaaatcat tgataaaaat ttaaatataa
     1981 atgaacaagt tttcatttac aaagcaacaa ataatttact aacactgcgc tctaataaaa
     2041 aacaattaga ttacactttt agtttggatt ctccaaaaaa gctcgtattt attttgacaa
     2101 cgaatgatgg gacagaaggg acagctaaac caattgaatt ttttaaagct gattgatgaa
     2161 tagttgtttg atattacaaa acaataattt caccgaaggt gaaacaagcg aaactttaca
     2221 aaaagtggct agcatttgct agcctttttt gtattgtgga gcgtgggttt tgagggggat
     2281 tcaaggggga gcttgcgccc ctttgaaaag cggttatttg caccaaatac gtaggtattt
     2341 ggctagcaaa tatagagctt gccaagccct tttggtgagc tttactcatt gtgccttttt
     2401 aggtacaatg gtattgcgaa cgatacgtcc gtaggacgta ctgaaagggt gggacttatg
     2461 agcgaacaaa atcaaaattt ggctagcgat cattctaaaa aatataccta tcgatccaag
     2521 ccaaaacaaa tcagttttcg agtgagcgaa tctgaatttg caaagctgaa gcagtcagct
     2581 gaagctttgc aaatgagtgt gccggctttc gtgaaagcca aggcacaaaa cgcgcgtctg
     2641 gtgacaccga aagtggcgcc agacattgcc caggcaatcg cgcgcgattt agccaaagct
     2701 ggagggaata tcaatcaaat tgccaagtgg tgcaatacac accaacatga cgttgctcct
     2761 ggagacgccc aacgtttatc cgaaaaccta aaaatcatgc aaaaggagct acaaaagata
     2821 tggcaacagt taaagtaagt cgaaccactt cctgtagccg agcaatcaat tacgcagaac
     2881 cacgagcaac cattaaaaca ggaataaact gtgacgtcga ttatgccaaa agtgaaatga
     2941 aacaaattcg catgctgtat ggaaaagacg accgtgtaca ggcacactta ttgattcaat
     3001 cttttcgacc aggagaaatt accgctgaaa aagctaatca actaggggca gagtatgcaa
     3061 aaaaaatagc ccccgatcac caaacagcta tttacacaca tacagacaaa gaccatattc
     3121 ataatcacat tgtcattaac tccgttaatc tggagactgg aaaaaaattt caagctcatg
     3181 gtcaagcatt tctaaacaaa tgttatgacc taaatgacga gatttgtctt gcacataact
     3241 taccaatcac tgagcgagga aagaaaccag aaaaacgaac catgtctgaa ataaaattaa
     3301 aagaaaaaaa tgaacctgtt tggaaagacg aaattcggat tgcgatcgat caaacaatga
     3361 aaaacaaaaa aaccagaacc tatgaccaat tttgtaattc cctcaaaaca ttggggattc
     3421 attgcttcaa tcgcgggaaa aatttcactt acgaattgat ccacaaaaag aaaaaagtac
     3481 gatccaacag actaggaaag gactacgaaa aggagacgat tttacatgag ctggacagac
     3541 gagaacgaac ctataaccaa cagcgaacca acgagctacg aagagctcga gctagcattc
     3601 gcgaaactgc agaagaagta cgaagagaac aacgaactct tacgcctgaa caaccggaaa
     3661 ttagaccggc tcgaagaaac catgaacaac acgttgaaag aggaacagac caccaacaag
     3721 aattatcgct ctaaaacgtt aaaagacata gaaaacgaaa taaagaaaca acgtgctttt
     3781 ctcgttcctt atacgcaaga aaggatacaa actacgattg atttacaagt taaaaaactc
     3841 catcaagagc tattagacca gcgaaataag gaacagaaaa aggtgcttat tcaacgatca
     3901 ttggattttc ttgccccctt atgttgctta gtcctgacac tgttcgcatt ttggttagta
     3961 tggggaggct aaaatggcat tttatttacc ctatctactc atttttgtta gtatttcagg
     4021 aagtatttgg ctcatctata aaatttttca aacaagatat tcattaaaag gctctaaaat
     4081 tcgatttaag cgatttttct ttcttggctg tatattttcc ttgataatcg tttcaagcgg
     4141 cttattcggc gttttagagg gaaataagcg cgtttctaga agtattttat taggaaatgt
     4201 cactcaaaag tatgaatcag cgcgtgataa aaagaaaaaa gagcaagcat tagcacaaaa
     4261 aatggaagag tttaccactt gttatgagga aatgaacgat atttttgtga atcaagaaaa
     4321 acgtttgacg gataaaaaca tggaaaaact cactcgtctt tatcaaaact tgccagaaaa
     4381 acagcaaaaa gaggttcaag acaactatga gcgaaccaaa aaagacgtgc aatatgtgaa
     4441 agatacgaaa gtggaagaag cttgtagtga tttatttgga gatacaattc ctttttcaac
     4501 tagcgaacaa gaacgaaaag aacgacaaca atcagtcaca tatgaacgct atgaaatctt
     4561 gcttcaacaa gcaattaaca tacaaaatct gactaaaaaa gaaacagctt taaattattt
     4621 aaaaagcgtc aaggaatggt tagatcagca acagcaaaat tgaatttgat tgaaattcat
     4681 gttaaactaa acatgcaaat gttcaaacat tagatacacg aaagccccag agaggtcgga
     4741 ttctctgggg ctttttttag gttgatgtcg cctttactga ttttacttct tgtttcggtt
     4801 attcaaccaa taactgaata cagagataca aactcctaca agaagggggc aaataaacag
     4861 ttcaaacatc agatacacct ccttccagtc gcaagactgt cggataggcg acaagttatt
     4921 ataccctaca aaattaaatc tgtgtggcaa ttttaagtat ctcttatttc cgggttgtta
     4981 gggcttgccc tgaccgcctg tagggcgctt taaattccag ataaagtttt ttatactaag
     5041 actgtcttaa aacggcttag acaagctctt agagcctcaa ccctcctttt tgaacaatgg
     5101 ttttagcaaa ggagctggag gcgactgcgc aggtataatg tgagagcgta gcgatcacac
     5161 ctttttggcg accgtaggga gcgaggtttt gaattagcag tttagaaaag ttcgcgaacc
     5221 tgtttaaaga aaaaataatt gtttttttag gtgggaaatt ttgtctccct cttttataat
     5281 ctttttttaa acctcttttt aaacctcttt aacgtcggct gtgtccttac tcccccaagg
     5341 tatacaaaat tttataggca tgaaattatc tgtttatagg catgaaatta tctgtttata
     5401 ggcatgaaat tatctgttta taggcatgaa attatctgtt ttaggtattg tttttagaca
     5461 taatatgtcc taaaatgatg tcaataaaat catttagact ggagtaacaa ctaaatggca
     5521 aatgaaatcg taaagtatga accagaatta aataccattc ctttaagaaa atttacccca
     5581 atagaaatga acttgttttt ttctattgtc tctagaatgc gcgataaagg taatcaaaaa
     5641 atacgctttt atttcagcca acttaaagat ttaagtgcgt ataagcagac tgcaggagaa
     5701 gtctttataa aagatttggc aagaacatac gatcatttga tggatttacg tttcggaaga
     5761 aaaagcaatg gtggattaac aatagaacga tttacaatgt ttactgattt tgaaattcat
     5821 ggagaagtcg ataaccctta tgtagatata aaagtccacg aaaaagcttt gcctttactt
     5881 aataatctag aaagctgggt acgtttctct ttaacagaat ttcgagattt aaatagcagt
     5941 tatgctaaaa caatgtttag attgctaaaa caataccgaa ctcaaggatg ggctgaattt
     6001 tctaaggaag attttttaga gctattagat attcctaaaa gctatagaca aacaaatata
     6061 aatcagtttg tactcaaacc aataaaagaa gaactaactc cactatttaa aggattaact
     6121 attcgtaaaa aatatggtaa aggtcgaggt aaacctgtta ttggttatcg ttttacttgg
     6181 aaagctgaaa tcaaccatgc tgacgatttt tcaaaaggga agcaagaaga tttacgtata
     6241 aaattattta atattgaaca caatggagaa ttaacacaaa aagaaaaatg gcgtgctaaa
     6301 gatcgaatac taaatcttcc gttaggtact catgaagctg attttaaaaa acaacaacaa
     6361 accgaaaaag aagaagcgga aaaacaatca atctcaaatg agcttaaaca agatttatta
     6421 gaaaacttac aaaacttatt cgattgaagc ataaggagta tttatgatag ataaaacgat
     6481 caaagaactc gcggaagaat ttcatgtttc aaaacaagca attaggaaaa ggctatcagc
     6541 tgattttaga gaaaactatg tgcaaactgt tactaggaac ggagtgaaaa ccttagttgt
     6601 cagctacaaa ggatatttgc ttttaaaaca acatttttta ggtagtaaca ccactggtaa
     6661 ccaagtagaa accgttgcta gtaacgatga aaactcgatt attgtttttt tacatgaaca
     6721 gctccaagaa aaagatactc aaataaaaca aatgcaaaag ttactcgacc agcaacaaca
     6781 actcaccttg caggcaaatc aacagatcga aaaactgcaa gaacagttac aattagctta
     6841 tacggaagaa cctgaagaag aggaattaac ttctgtcaat aaagaaaaca acaatgcaat
     6901 aacaacagaa aaaaagtggt ggaaattttg gtaacaatta ccaactttcc ataaagaaga
     6961 aatcaatttc tatagactct atctttctaa gaataaaaaa tatgtttagg tgatcaaatg
     7021 actataagta aagtaatcaa acaaaaaaga atagaaaaac aactaactca agaagattta
     7081 gctgaaatgc ttttagtatc taaaaaaacc atttctaatt gggaaaatgg tcgaacaata
     7141 ccagatacag aaaatttaat tcagtttgct aagttatttg atttatcact agacaatatt
     7201 ttgttaggag aagaaaaaat tatggtaaaa aattatggta aaaaatcata caaaaacact
     7261 aatactatta tttcattttg taattttttt aagtttagtt ttcaccttaa ttcagtccgg
     7321 attcttttat tttagccatt caattgccac ttggttatta atattttttc taagtttact
     7381 attaataatt aatacattaa taattaatac tttaattatt atctttaata aacatagaaa
     7441 cttatttctt cacagcatat ttccaattgt tttattaatt tttctatact ttatataaaa
     7501 agatagaact atttagtaag ataaaaaagt agctaattgt aattttcgtc taaaactcaa
     7561 aactagtaaa aataacttta ttgtgttatt tttatttata aattatgaaa aaggaccttt
     7621 cgaaatgaaa aataatagaa tctacaaaaa tcagttgaat tatgggcttt tattgccagt
     7681 ttttctgcta tgtatcattg gattactttc tttatatgtt gctttatatc acgactctta
     7741 cactaattca aaaatcacaa aagaattaat taaacaagta ttgtggtata gtattgggtt
     7801 cacttcagca ataactattt atttttttaa tcctaaaatt ttgtggaaat taactcctat
     7861 attttacgga ttatgcatca taatgttatt acttctcttg aaattctata atccacaatt
     7921 agcagtctta actggagcaa aaaattggtt ttatattgct ggtttttcgt ttcaacctac
     7981 tgagttagtc aaaataggat acacccttat gctagctaaa ataaccgtca attatcagca
     8041 aaaatctatt actagtaata cgaaagatga ttggatttat ttacttaaaa cttttattgc
     8101 tactcttcca ataggaatat tattattttt tcagaacgat ctaggaacaa tgttagtctt
     8161 cattgttatt tatattttta ttttgtttac gtctaacata aatataaaaa taattgcccc
     8221 aataatcgcc attggtgttg ttttatcctt aatattttta tatttggtta tatcagatac
     8281 aggaagagat ttcttattaa aaataggatt tcacgactat cagtttaaaa gaatagactc
     8341 atggttgaat ccatttttag atccaaatgg atctagctat cagttagcaa atagtttaat
     8401 tgctattggc tctggcggac ttttaggtac tggttttaat gtatcaaaca ttcacgttcc
     8461 tgttagagaa tccgatatga tattttctgt aattggagaa aattttggct ttataggaag
     8521 ttgtcttgta atattcctat acttttattt aatttatcaa atgtataaaa catgttttaa
     8581 aagcaataac ttatttttca cctatatcgg tataggcatt gttgcaatga ttttttttca
     8641 tgtttttgaa aatataggtg caagtatcgg attactacct ctaactggta ttccactccc
     8701 ctatattagt caaggtggtt ctgccattct tagtaatttt ttggggttgg gatttatgtt
     8761 gtgttgtagt agatatacta acgaaaaaaa aggaacacaa aaatgaattc aaaataacac
     8821 tttatgaata gaatgtctat ttcaataaaa attatgatac cttaaagtta atc
//
LOCUS       DAFBVQ010000084         8661 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.087, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000084 DAFBVQ010000000
VERSION     DAFBVQ010000084.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8661)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8661)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8661
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.087"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(178..735)
                     /gene="frr"
                     /locus_tag="LLC22_002512"
     CDS             complement(178..735)
                     /gene="frr"
                     /locus_tag="LLC22_002512"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosome recycling factor"
                     /protein_id="HBK5435733.1"
                     /translation="MADAIMTEAKEKMKKAAQNLQRELGQIRAGRANASLLDRITVNY
                     YGAPTPLNQMASIQIPEARVLMITPFDKSILQDVEKAIMASDIGISPTNDGNVIRLVI
                     PQLTEERRKELAKDVKKEAENAKIAIRNIRRDAIDEYKKQQKNGDITEDDLRGLEKDV
                     QTLTDNSIKEVDKIAADKEKELLEV"
     gene            complement(738..1460)
                     /locus_tag="LLC22_002513"
     CDS             complement(738..1460)
                     /locus_tag="LLC22_002513"
                     /EC_number="2.7.4.22"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875937.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="UMP kinase"
                     /protein_id="HBK5435734.1"
                     /translation="MVTPKYQRVVLKLSGEALAGDAGFGIKPPVIKEIIQEIKEVHEL
                     GVEMAIVVGGGNIWRGQIGAQMGMERAQADYMGMLATVMNALALQDTLENVGVPTRVQ
                     TSIEMRQIAEPYIRRKAERHLEKGRIVIFAGGTGNPYFSTDTTAALRAAEIGADVILM
                     AKNNVDGVYSADPKVDANAVKFEELTHLEVIAKGLQVMDSTASSLSMDNDIPLLVFNL
                     NEHGNIRRAILGENIGTTVRGK"
     gene            complement(1596..2477)
                     /locus_tag="LLC22_002514"
     CDS             complement(1596..2477)
                     /locus_tag="LLC22_002514"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722834.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor Ts"
                     /protein_id="HBK5435735.1"
                     /translation="MADVTAKMVKELREMTGVGMMDAKKALVEVEGDMEKAVDLLREK
                     GMAKAAKKNDRIAAEGLASVAVKGNTAAIVEVNSETDFVSKNEMFQDLVKEIAELVAE
                     NKPADMEAAMKIKTDKGTIESDLIEATQVIGEKISFRRFEVVEKDDNAAFGGYLHMGG
                     RIAVLTVLDGTTDETVARDVAMHVAAINPRYVNESQIPEAELEHEKTVLTEQALNEGK
                     PANIVEKMVEGRLKKFKAEIALVDQPFVKDPDMTVEKYVASKGATVKTFVRFEVGEGI
                     EKREDNFVEEVMSQVKK"
     gene            complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LLC22_002515"
     CDS             complement(2576..3358)
                     /gene="rpsB"
                     /locus_tag="LLC22_002515"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="30S ribosomal protein S2"
                     /protein_id="HBK5435736.1"
                     /translation="MAVISMKQLLEAGVHFGHQTRRWNPKMKKYIFTERNGIYIIDLQ
                     KTVKLVDAAYDYMKSVAEEGGVALFVGTKKQAQEAIKEEATRAGQYFVNHRWLGGTLT
                     NWDTIQKRISRLKQINAMEEDGTFEVLPKKEVAGLNKERERLEKFLGGIADMPRIPDV
                     MYIVDPRKERIAVQEAHKLNIPIVAMVDTNCDPDEIDVVIPSNDDAIRAVKLITSKMA
                     DAFIEGNQGEDQVVEEDFTEENTATSIEEIVDVVEGDNSSAE"
     gene            3717..4196
                     /locus_tag="LLC22_002516"
     CDS             3717..4196
                     /locus_tag="LLC22_002516"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ArgR family transcriptional regulator"
                     /protein_id="HBK5435737.1"
                     /translation="MRKAQRHLLIKQVIEEFPIRTQEELLNKLGHYGVTATQATISRD
                     IRDLKIVKAPDENGVSRFVLFREKGTPETRTEEEDRLVQMIEDIVLKVERVHFLTIVN
                     TLPDNAHLFASVLDEIKPPSIVSTIAGFDTIMVISENEEDAKRVEEFLHHPTEVSLF"
     gene            4413..5504
                     /gene="phnW"
                     /locus_tag="LLC22_002517"
     CDS             4413..5504
                     /gene="phnW"
                     /locus_tag="LLC22_002517"
                     /EC_number="2.6.1.37"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347278.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-aminoethylphosphonate--pyruvate transaminase"
                     /protein_id="HBK5435738.1"
                     /translation="MYKLLTSGPLTTSETVKNAMLIDHCTWDQEYKEITQWIRKKLLD
                     LAQVSEGIYTTVLMQGSSSFGVESVLSSVIRPEDTVLICSNGAYRQRMINMCECLKLN
                     YTVYEVSEHQILQAHVITQLIEENPSISALAMVHSETTSGILNNLEEIAAVTQERDLL
                     FIVDAMSSFGGIPICVAELGIDFLISSSNKCIQGVPGFSFVLANKAELEKRKNVSRSL
                     SLDLYDQYRVMENENGKWRFTSPTHTVLAFQQALKELEAEGGIETRYSRYLANNHVLR
                     QKMTEMGFQPFIQEYQGPFITSFLYPKDWRFDFNHFYQYLKQNGFVIYPGKISDHECF
                     RIGNIGEIYPEDILELTAIIKDYKENVND"
     gene            5497..5625
                     /locus_tag="LLC22_002518"
     CDS             5497..5625
                     /locus_tag="LLC22_002518"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBK5435739.1"
                     /translation="MIKTVIFDWAGTTVDFGCMAPVHAFRNAFLEKGTQLTDKEIR"
     gene            5629..6174
                     /locus_tag="LLC22_002519"
     CDS             5629..6174
                     /locus_tag="LLC22_002519"
                     /EC_number="3.11.1.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphonoacetaldehyde hydrolase"
                     /protein_id="HBK5435740.1"
                     /translation="MGKLKWDHIQQLLSLPSVKKQWIAIYGQLPQEKEVEELYQQFEH
                     YLFKDLVKHSTLKPDTLETIERLRNAGINIGSTNGFNAPMMTIVAETAKKERYSPDFM
                     ATFEDVEGYGRPFPYMIHKNMQYFKNKSVDEVIKVGDTVSDIQEGKNAGVLTVGVIEG
                     SSLMGISYDEYQKLEMGKKIV"
     gene            complement(6628..8319)
                     /locus_tag="LLC22_002520"
     CDS             complement(6628..8319)
                     /locus_tag="LLC22_002520"
                     /EC_number="6.1.1.19"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arginine--tRNA ligase"
                     /protein_id="HBK5435741.1"
                     /translation="MNNKDLVAKAVYDAVKDDLTLEQVEQLLENPKSAEHGDVAFPAF
                     SLAKVYRKAPQQIAADLAEKIDSANFEKIEVVGPYLNFFMNKELISKKVLQTVVKEKE
                     HYGDSNIGNQGTVPIDMSSPNIAKPISMGHLRSTVIGNSIGFIMEKIGYQPIRINHLG
                     DWGTQFGKLIVAYKKWGTEEAVKAEPINELLRLYVQFHEVAETEPELNEEARAWFKRL
                     EEGDKEAIQLWQWFRDESMKEFNKIYDLLEVRFDSLNGEAFYNDKMDEIVKLLEEKHL
                     LNEDKGAEIVDLSAYDLNPALIKKSDGATLYITRDLAAALYRKRTYDFKQSLYVVGNE
                     QSYHFKQLKAVLKEMGFDWSDDMHHIPFGLITQGGKKLSTRKGKIVLLEEVLNEAIQS
                     AKEQISEKNPDLENKDAVAKQVGVGAVIFHDLKNDRLNTFDFNLEEVVRFEGETGPYV
                     QYTHARAVSLLEKAGFVPSETADYALNDDTSWEVVKLVQKYPETVLSAGEKYEPSVIA
                     KHAIKLAQAFNKYYAHTKILADDEQKEARLALVYAVTVLLKEDLRLLGLHAPDKM"
BASE COUNT         2410 a         1771 c         1568 g         2912 t
ORIGIN      
        1 ttaaaagatt cccactatct taagtattat agcaatatct aactgttttt cctatgaaat
       61 cattgttttt ttatttaaaa actgaataat tttttctttt tttaattttt aaataaaaga
      121 aatataaata aaaacagagg aagcggaatg atccgcccct ctgtttttat gattttatta
      181 aacttccaat aattcttttt ctttatcagc agcgatctta tctacttctt tgatgctgtt
      241 atctgtcaat gtttgtacgt ctttttctaa tccgcgcaaa tcatcttcgg taatatcacc
      301 atttttttgt tgttttttat attcatcgat cgcatcacga cggatgttac gaatcgcgat
      361 ttttgcattt tctgcttctt ttttcacatc tttagctaat tcttttctgc gttcttctgt
      421 cagttgcggg ataactaagc gaatgacatt tccatcattg gttggactga ttccgatatc
      481 acttgccata atagcttttt caacatcttg aagaatgctc ttgtcaaaag gtgtgatcat
      541 taaaacacgt gcttctggaa tttggattga tgccatttgg ttcaatggtg ttggcgcacc
      601 gtagtagttc acagtaatac ggtccaaaag gctagcgttc gcacggcctg cgcggatttg
      661 cccaagttca cgttgaagat tttgtgctgc ttttttcatt ttttcttttg cttctgtcat
      721 aattgcatct gccattttta tttccccctt acagttgttc cgatattttc gcctaagatt
      781 gcacggcgaa tatttccgtg ttcatttaaa ttgaagacaa gcagtggaat atcattatcc
      841 atgcttagtg aacttgcagt tgaatccatg acttgtaatc ctttggcaat aacttccaga
      901 tgagtcagtt cttcaaattt tactgcattt gcatctactt tcggatcagc agaataaaca
      961 ccgtctacat tgtttttagc catcaggata acatctgcgc cgatttctgc cgcgcgtaat
     1021 gctgctgttg tgtctgtcga gaagtacggg ttgccggtac cgcctgcaaa gataacgatc
     1081 cgtccttttt ctaaatgacg ttctgcttta cggcgaatat atggctctgc gatttgacgc
     1141 atttcaatcg aagtttgcac gcgtgtcggt acacccacgt tttccaacgt atcctgtaaa
     1201 gctaaggcat tcataactgt agctaacata cccatgtaat cagcttgagc acgttccatg
     1261 cccatttgtg ctccgatttg tccgcgccag atatttccgc cgcccacaac gattgccatt
     1321 tcaacgccca gctcgtgaac ttctttgatt tcttggatga tttctttgat tactggtggt
     1381 ttgattccaa atcctgcgtc cccagctaaa gcttctccac tcaattttaa gactacacgc
     1441 tgatatttcg gtgtgaccat gttcattcct ccaatatttt ctattgccat tttaccatac
     1501 ttagatgatt tcgacactct aagactggtt tttcttgttt tgcttaaaaa aagggagcgc
     1561 acaaaccgtg cgttcccgtc tgttattcaa cagaattatt ttttcacttg gctcataact
     1621 tcttctacaa agttatcttc gcgtttttcg ataccttcgc caacttcgaa acgtacgaat
     1681 gttttaacag ttgcgccttt tgatgcaacg tatttttcaa cagtcatatc aggatcttta
     1741 acgaatggtt ggtccaccaa agcgatttct gctttgaatt tcttcaagcg tccttctacc
     1801 attttttcaa cgatattcgc tggtttgcct tcgttcaatg cttgttctgt aagaacagtt
     1861 ttttcatgtt ctaattcagc ttctggaatt tgtgattcgt ttacataacg aggattgata
     1921 gctgctacgt gcatagctac gtctcttgca actgtttcgt cagttgttcc atctagaaca
     1981 gtcaatacgg caatacgtcc gcccatatgc aagtatccac caaatgcagc attgtcgtct
     2041 ttttctacaa cttcaaagcg acggaagctg attttttctc cgataacttg agttgcttcg
     2101 atcaagtcag attcaattgt acctttatct gttttgattt tcattgcagc ttccatgtct
     2161 gctggtttgt tttcagcaac aagttctgca atttctttta ctaaatcttg gaacatttcg
     2221 tttttagaaa caaagtctgt ttctgagttt acttcaacga ttgctgcagt gttacctttc
     2281 acagcaactg aagccaatcc ttcagctgca atgcggtcat ttttcttcgc agcctttgcc
     2341 attccttttt cacgtaaaag atcaactgct ttttccatgt cgccttctac ttcaactaat
     2401 gcttttttcg catccatcat tcctacgcca gtcatttcgc gtagttcttt taccatttta
     2461 gctgtaacgt ctgccatgtt taactcctcc tgtgtgtttt tctttttaaa aaaagctgct
     2521 tcaaaggaga gtgaggcttg tcgcccagcc tttgaaacag ctccatcatt caaaattatt
     2581 ctgctgaaga attgtcgcct tcaacaacat ctacgatttc ttcgattgat gttgctgtgt
     2641 tttcttctgt gaaatcttct tcaactactt gatcttcacc ttggtttcct tcgatgaaag
     2701 catcagccat ttttgaagta atcaatttaa cggcacgaat tgcatcgtcg tttgaaggga
     2761 ttactacgtc gatttcatct ggatcgcagt ttgtatcaac catagctacg attgggatat
     2821 ttaatttgtg tgcttcttga acagcaatac gttctttacg tgggtcaacg atgtacatta
     2881 catctgggat tcttggcata tcagcgatac cgcctaagaa tttttcaaga cgttcacgtt
     2941 ctttgttcaa accagcaact tcttttttag gtagaacttc aaaagttcca tcttcttcca
     3001 ttgcattgat ttgtttcaaa cggctgatac gtttttggat agtatcccag tttgtcaatg
     3061 ttccgcctaa ccaacgatgg ttaacgaagt attgtcctgc acgagttgct tcttctttga
     3121 ttgcttcttg tgcttgtttt tttgtaccta cgaataatgc tacgccgcct tcttcagcaa
     3181 cgctcttcat gtaatcataa gctgcatcta ctaatttaac tgttttttgc aagtcaatga
     3241 tgtagattcc gtttctttct gtgaagatat atttcttcat ttttggattc cagcgacgag
     3301 tttggtgacc aaagtgtacg ccggcttcta gtaattgttt catagaaatt actgccatgt
     3361 ttgtttcctc cgatttggtt ttatttttcc tcttcttatc ttctaccttg ccggcaaact
     3421 ttttcaagca cctaccgaca atccaataag aatgtggatt tgctgatgca taaagcaccc
     3481 tcagctatta tacagacaaa agatccgtat cgcaagagca aatatacttt tctgctcaac
     3541 attcaatagt ttacctgaaa gataaaaaga attcaagaaa aacagtagat ttctctttgt
     3601 ttctttatta tcctttttcc ataaaataat tttaggtata aaagacgaat attattgggc
     3661 aatccttctt ttttttgtta tgatacatgt gaaatctttc gtaaaggaga aagaaaatgc
     3721 gcaaagctca aagacatttg ctgattaaac aagtcattga agaattcccg atccgtacgc
     3781 aagaagaact attaaacaaa cttgggcatt atggcgttac cgccacgcag gcaacgattt
     3841 ctcgagatat ccgtgatcta aaaatcgtga aggcacctga tgaaaatggc gtttcccgct
     3901 tcgtattgtt tcgcgaaaaa ggaactcctg agactaggac tgaggaagag gatcggctgg
     3961 ttcaaatgat tgaagacatt gtattgaaag tcgaacgagt ccactttttg acgatcgtca
     4021 ataccttgcc agacaatgct catttatttg catctgtttt agatgagatc aaacctccct
     4081 ctattgtcag tacaattgct ggattcgata cgatcatggt catctcggaa aatgaggagg
     4141 acgcaaaacg agtagaagaa tttcttcacc atccaactga agtatcactt ttttaatcag
     4201 agcacgtatt cctaatatgg aatgcgtgtt tttttatttt caatattttc cttattgaat
     4261 aaacctttac actctttaca aaaatacatc attttttatt caaatttttc aacaccttga
     4321 ttgaatcaca ataatcatca tttatattgg atgttaacaa gagcagcttc ttgctctttg
     4381 tgtatttcaa aaaagaaatg aaaggaaatc atatgtataa attattaact tctggaccat
     4441 tgacgacttc tgaaacagtg aaaaatgcta tgctgatcga tcattgtact tgggatcaag
     4501 aatacaaaga aattacacaa tggataagaa aaaaattatt ggatcttgct caagtatcgg
     4561 aaggaatata cacaacggtc ttaatgcaag gtagcagctc cttcggggta gaatcggtat
     4621 taagttctgt gatcaggcca gaagatactg tactgatttg ttcaaacggc gcatatagac
     4681 aacgaatgat caacatgtgc gaatgtctga aactgaacta taccgtttat gaggtatcgg
     4741 aacatcaaat cctccaagct catgtgatta cacagctgat tgaagagaat ccgtctatct
     4801 ccgcactagc aatggtccat agcgagacta cttccggtat tttgaataat ttggaagaga
     4861 ttgctgctgt cacacaagaa agagatcttt tgtttatagt ggacgcgatg tcaagctttg
     4921 gtgggatacc gatttgtgta gccgaactag ggattgattt tttgatttcc agctcaaaca
     4981 aatgtattca aggtgttcca ggcttttctt ttgtacttgc taataaagcg gaactggaaa
     5041 aacgaaaaaa tgttagccga agtttgtcac ttgatctata tgaccagtac cgcgtgatgg
     5101 aaaacgagaa tggcaaatgg cgtttcactt cccctaccca tacggttttg gcttttcaac
     5161 aagcgctgaa ggaactagag gcagaaggag gaatcgaaac tcgatattca cgttatctcg
     5221 ccaataatca tgtgctacga caaaaaatga cagagatggg gttccagcct ttcattcaag
     5281 aatatcaggg gccattcatc acctcttttc tttaccctaa ggactggcga tttgatttta
     5341 atcattttta tcagtattta aagcaaaatg gatttgtgat ctatcccggg aaaatcagcg
     5401 atcatgaatg ttttcgtatc ggaaatattg gcgagatcta tccggaagat attttggaac
     5461 tgacagcaat tatcaaagac tataaggaga acgttaatga ttaaaactgt aatttttgat
     5521 tgggcaggaa caactgtgga ctttggctgt atggctcctg tccacgcttt tagaaatgct
     5581 tttctagaaa aaggaaccca actgactgac aaagaaatcc gctaaccgat gggaaaatta
     5641 aaatgggatc atatccaaca gcttctttcc ctcccttctg tcaaaaaaca atggatagct
     5701 atttatggac aactacctca ggaaaaagag gtggaggaat tgtatcaaca atttgaacat
     5761 tatctgttta aagatttggt caagcattct accttgaaac ccgacacatt ggaaacgatc
     5821 gaacggttga gaaacgctgg gatcaatatt ggttccacga atggatttaa tgctcctatg
     5881 atgacaatcg tagcagaaac cgcaaaaaaa gaaaggtatt caccagactt catggcaact
     5941 tttgaagacg tcgaagggta tggtcgaccg tttccttata tgatccataa aaacatgcag
     6001 tacttcaaaa acaagtcggt tgatgaagta atcaaagtcg gagatacggt ctcagatatc
     6061 caggaaggga aaaatgccgg agtgttgaca gtaggtgtaa ttgaaggtag ttcgctaatg
     6121 gggatttctt atgatgagta ccaaaaatta gagatgggga aaaagatcgt ttaaaacagt
     6181 ctgttgctct tagattccaa caagccggcg ctgatatttg tgtaaacaat ttaaaagagt
     6241 taacagaata cattttgtac gctgacaaga atccagaatg acttttatac aaaataagag
     6301 gttgtgaaaa agctgtcctg tatcaagtaa taaaaacagc caagcaaaaa tagctcctca
     6361 tatttttcgt ttggttaggc ttattaccgc agatgcaagc ttttgaacac cgtttattcg
     6421 aaaaaaaaaa gggagctgtg acacgacttt tgtcacagtc cccttatttg caaacaaaca
     6481 gtgtttaaga gacaacctct ccactaaacg gtgttcattc agctgactct cggtatttgc
     6541 tcaaaaaacg ataaaatttg aaaagctatt ttctcttttg tttctctaat actcggatca
     6601 gaacgctgat ttcacattct ctttttctta catcttatct ggtgcatgaa gtcctagcaa
     6661 acgaaggtct tctttcaata atacagtcac tgcataaact agagctaagc gtgcttcttt
     6721 ttgttcatca tcagctaaaa tcttcgtatg agcatagtat ttgttgaatg cttgtgctaa
     6781 tttgattgca tgtttcgcaa tcactgacgg ttcgtatttt tccccagcag acaagaccgt
     6841 ttcagggtat ttttgaacta atttaaccac ttcccagctg gtatcgtcat tcaatgcata
     6901 gtctgctgtt tctgaaggga caaatcctgc tttttccaac aggctgactg cacgagcatg
     6961 tgtatattgc acataaggtc cagtttctcc ttcaaatcga acaacttctt ccaggttaaa
     7021 gtcaaatgta ttcagtcgat cgtttttcaa atcgtggaaa atgactgccc caaccccaac
     7081 ttgtttagct acagcatctt tgttttccaa atcagggttt ttctcgctga tttgttcttt
     7141 agcagattgg attgcttcat ttaatacttc ttctaataag acgatctttc ctttacgagt
     7201 tgataatttt ttaccacctt gcgtgatcaa accaaatgga atatggtgca tgtcgtcaga
     7261 ccagtcaaag cccatttcct tcaagacagc tttcaactgt ttaaaatgat agctttgttc
     7321 attccctact acatatagag attgtttgaa gtcgtaagta cgtttacggt acaatgcagc
     7381 agctaagtca cgtgtaatgt atagtgtcgc accgtctgac ttcttaatca acgctggatt
     7441 caggtcataa gcagataggt caacgatctc tgcaccttta tcctcgttca gcaaatgttt
     7501 ttcttctaaa agtttgacga tttcatccat cttgtcattg tagaaagctt caccgttcaa
     7561 cgaatcgaaa cgtacttcca gcagatcata gattttattg aattctttca tcgattcatc
     7621 acggaaccat tgccataatt gaatagcctc tttatcgcct tcttccagac gtttgaacca
     7681 agcacgagct tcttcattta attctggttc tgtttcagct acttcatgga attggacgta
     7741 taaacgaagc aattcattga ttggttctgc tttaacagct tcttctgtac cccatttttt
     7801 gtaagcgacg atcagttttc caaactgtgt tccccagtca cctaaatggt tgatgcggat
     7861 tggctgataa ccgatttttt ccataatgaa accgatcgaa ttaccgataa ctgtcgaacg
     7921 caaatgtccc attgagattg gtttggcaat attaggagaa gacatgtcga ttggtactgt
     7981 tccttgattc ccgatgttgc tatccccata atgttctttt tctttcacta ctgtttgcaa
     8041 aacttttttg ctgataagtt ctttattcat gaaaaagttc aagtaaggtc cgacaacttc
     8101 gattttttca aagttggcag aatcgatttt ttctgctaaa tctgcagcga tttgctgtgg
     8161 cgcttttcgg taaacttttg ctaatgaaaa ggctggaaat gcaacatctc cgtgttcagc
     8221 tgattttgga ttttctagta attgctcgac ttgttccagt gttaaatcat ctttgacagc
     8281 gtcatagaca gcttttgcga caagatcttt attattcatc tttattcctc ctaaagtgtt
     8341 cccttgattg ttaaacaaaa aaaatctcta gcgacggcat acttagtatg ccatcactag
     8401 agacgagatt tcccgcggta ccactccaat tgtcctaaaa aaggaccagc tccatctgat
     8461 atcggtagac gaccgtctgt ttaaaacaga attctccaag tgcgcttcgt tgtatcttct
     8521 tcattcggct tccaccactt ccgaattcgc tagccaagaa tgatacaagt actctcttgt
     8581 tcaacaaatc ttagtcttat taaactttct tgaattatat cagaaaaaaa aacgaaaggc
     8641 tagtcgtttc ataaaaaaaa a
//
LOCUS       DAFBVQ010000085         8512 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.088, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000085 DAFBVQ010000000
VERSION     DAFBVQ010000085.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8512)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8512)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8512
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.088"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(132..1085)
                     /gene="menA"
                     /locus_tag="LLC22_002521"
     CDS             complement(132..1085)
                     /gene="menA"
                     /locus_tag="LLC22_002521"
                     /EC_number="2.5.1.74"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328810.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="1,4-dihydroxy-2-naphthoate
                     polyprenyltransferase"
                     /protein_id="HBK5435742.1"
                     /translation="MTLKIFLEVVEIRTKVASVFPFAVGVLFSIAFFHEIHWLNTFLF
                     FIGMLVFDLATTAINNYMDYEKAHSEVYKYEENVIGRRNLSPVLIRNMILAMIAFVFV
                     IGVILTINTGWLLLLMGFICCFIGVFYTFGPIPLSRMPLGEIFSGVTMGLGIFAMVVY
                     VNTFGSDVYDLTVNFSSGQFDLVGNLWAIAAIVLASLPLVFTIANIMLANNLRDLDRD
                     IENHRYTLVFYIGRPAGTVLFQLLMYACYFVILMGLLSGIYEWPILVTFLTLPIVKKH
                     LDQFKQTLPQPISFSYSIKNMVLFNASYVLGLLLTIIMQAI"
     gene            complement(1098..2201)
                     /locus_tag="LLC22_002522"
     CDS             complement(1098..2201)
                     /locus_tag="LLC22_002522"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310577.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD:protein FMN transferase"
                     /protein_id="HBK5435743.1"
                     /translation="MRKKLLFSLITLGISFMVLTGCSNSANKTTTESSAATKILKDPY
                     SDEQFLLGTYVRIRVYDEGKESALKPAFDRVKELGDKITINQKGSEIDEVNEQAGIKP
                     VKVSDDVYTLVKRAYEYSQDSQGGFDMAIGAITQLWRIGFDDARKPSQEEIDQALKLV
                     DYHKIELNDKEKTVYLKEKGMIIDLGAIAKGYITDEVVKVLKKQGVTTAIVDLGGNVY
                     VLGHSPRGENQDWTVGIQDPNMARGSVLGSIKERNKTLVTSGIYERYLEVDGKKYHHL
                     FDPKTGYPFDNDIASVTIITDKSIDGDGLSTAVFSMGVKKGLEYVESELNNGTEAIFV
                     TKDDKVYVTDPIKDTFKLSEDSHYTMGDRSELK"
     gene            complement(2291..3247)
                     /locus_tag="LLC22_002523"
     CDS             complement(2291..3247)
                     /locus_tag="LLC22_002523"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347154.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FMN-binding protein"
                     /protein_id="HBK5435744.1"
                     /translation="MEWWGIKMKKKRFVTGFAVLAFSALVLGACGADDNGSSNSSSES
                     STAQSSTAKSTTESSAKVVAGGDLQDGTYKLEEKNYSNGYRAVFEMVVKDGKITESKY
                     DNVNENGESKTKDAEYNKNMEAKSGTNPEKYIPELNDQFLKAQSASGVEVVTGATHSS
                     ESFQNYAQQLIQAAQAGNTDTIEIDNGADLKDGTYKLEEKNYSNGYRVQFEMTVAGGK
                     VTESNFDYIDKDGKSKQDDTEYNENMKAKSGTEPKTYIPTLNDEFVKAMGEEDGSPAN
                     VEVVTGATHSSHSFIMYAQQLVNAAEKGDTQTIEVDNIVTEK"
     gene            3528..5462
                     /locus_tag="LLC22_002524"
     CDS             3528..5462
                     /locus_tag="LLC22_002524"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324439.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NAD(P)/FAD-dependent oxidoreductase"
                     /protein_id="HBK5435745.1"
                     /translation="MAKQNIVVVGAGYAGVSATKYLAKKLKKEDVAITLIDRHSYHTM
                     MTELHEVAGGRVEPEAIQYDLQHLFARQKNVQLVTDTVIGIDKERKIVKTKLGSYPFD
                     QLILGMGGEPNDFGTPGVKAHGFTLWSFEDSVRIREHIEKTVAKAALEPDDELRKAML
                     TFVVCGSGFTGIEMIGELIDWKNRLAKDYKLDPNEITLMVVEAMPTILNMLDRNDAAK
                     AERYLRKHNVELLLNAPIVEVAADHIKLKDGRNIPTHTLIWTAGVKGTSDAADFGLES
                     ARGQRLIANEYMQAKGYEDKNIYIIGDLVFYEEFPGTPTPQIVQAAEQTGHTAAANIV
                     ASIKGGEKHKFKGNYQGFMVSIGAKWGVANLFDKIHLSGFLAIVMKHIVNLKYFFDIR
                     SGYYMFQYLMHEFFHIKDDRNVTRGHSSRYGNVLWSVPLRIFYGLVWFVEASKKIIGN
                     GEVFKPSTWFGEGSWFTGNSVFPWTWEYNVTDVASGASAAGDATTAASGAGASAGEAA
                     TQAAHFGLSYAYGEEPMAVIEKSPDWFTKIMQVIMPNNDVAMFFQKFMVFFEIALALA
                     LIAGLFTWLCSATTIVLVITFCLSGMFYWVNIWFIFVAFALMNGSGRAIGLDRWVIPW
                     LQRTLGNWWYGRPSSQYGKK"
     gene            5919..6335
                     /locus_tag="LLC22_002525"
     CDS             5919..6335
                     /locus_tag="LLC22_002525"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325493.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NusG domain II-containing protein"
                     /protein_id="HBK5435746.1"
                     /translation="MSLKEFAEKSLLKPWDVFIILLLTVLSFLPVMIFGLQQNTATAE
                     KEAVLRVDGTEIKTFPLMAGEESNTYTYKDEHGDYNLIEIDGDRVRIKEADCDDQICV
                     RRGWATKNGETIVCLPHKLVIEVRSTDGGDEDSLIY"
     gene            6349..6915
                     /locus_tag="LLC22_002526"
     CDS             6349..6915
                     /locus_tag="LLC22_002526"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332226.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Gx transporter family protein"
                     /protein_id="HBK5435747.1"
                     /translation="MSKLQKMIYISLLVAQGVIIGLLENMIPYPFSFAPGAKLGLANL
                     ITIVAIFTMKKQDSFLLLWLRLFLTTLLGGTISTFLYSMSGALLSYFGMLLVKQLGPK
                     RVSIIGISAAGGFMHNVGQLLMASFIAQSWTVMLYLPVLSVLGILSGIAIGIAANYLL
                     RHVQTLQRFQKDYEQGTKQKWSPMFTKK"
     gene            6938..7924
                     /locus_tag="LLC22_002527"
     CDS             6938..7924
                     /locus_tag="LLC22_002527"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310571.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="polyprenyl synthetase family protein"
                     /protein_id="HBK5435748.1"
                     /translation="MKLHPMWENYPALSKELTETLKRMEETVRLKNKPVEQAIKETIH
                     AGGKLLRPAYQLLFSQFGPEQDRDKAIALAASIEMLHTATLIHDDIVDEADLRRGQPN
                     IRSQFGNVVSVYAGDYLFVCCFKLLSDYSTSLKSLQLNSRSMEKVLNGELGQMDDRYN
                     YELSVKEYLENISGKTAELFQLSCSVGAFESGTSERFAKKAGDIGLSIGMAFQIIDDI
                     LDYTKESQEIGKPVLEDMRQGVYSLPLIYSLQKNKPKLLPYLEKKAAMTEEDVDAVRK
                     IVEHTGGVEEARKLAASYTEKALKEIKKLPATSLRTKENLFSLTQLILDRKD"
     gene            complement(8079..>8512)
                     /gene="scm"
                     /locus_tag="LLC22_002528"
     CDS             complement(8079..>8512)
                     /gene="scm"
                     /locus_tag="LLC22_002528"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="collagen-binding MSCRAMM adhesin Scm"
                     /protein_id="HBK5435749.1"
                     /translation="ASSDSTDTSTTTSDSTDTSASSDSTDTTSTTSDSTDTSASSDST
                     DTSSTTSDSSDSSTSSDSTDTSSTTSDTRHASVSFSKTSSDNRTNFNLTNKTSNDNGN
                     KSKRALPKTGSQSNNWITLAGVILLVIGLRITFMSYKKSKR"
BASE COUNT         2507 a         1643 c         1725 g         2637 t
ORIGIN      
        1 tgataaacgg tgttcaaaag cttgcatctg cggtaataag cccaaccaaa cgaaaaatat
       61 aaggagctat ttttatttgg ctgttcttat tacttgatgc agggcagttt tttcacaacc
      121 tcttcatgct gttaaatggc ttgcataatg attgttagta atagccccaa tacataactg
      181 gcattgaata agaccatatt tttgatggaa tagctgaaac tgataggctg gggtaacgtt
      241 tgcttgaatt gatccaaatg cttcttcaca attggcaagg tcaagaaggt gaccaagatc
      301 ggccattcat agataccgct caacaacccc attaaaatca cgaaatagca agcatacatc
      361 aatagctgga ataagactgt tcccgcagga cgtccgatat aaaaaactag tgtatagcga
      421 tgattttcaa tatcacggtc aagatcccgc aaattattag ccaacatgat attggcaatc
      481 gtaaacacca agggtaagga agctaatacg attgctgcta tagcccaaag atttcctacc
      541 aaatcaaatt gtccagatga aaagttgact gtcagatcat agacatctga accgaatgta
      601 ttgacataaa cgaccatggc aaaaattcca aggcccatag tcaccccact gaaaatttcc
      661 cctaaaggca ttcgagataa aggaatcggt ccgaatgtat agaatactcc aataaaacaa
      721 cagataaatc ccatcaaaag taaaagccaa cccgtattga tcgttagaat aacgccgata
      781 acaaaaacaa atgcaatcat agctaaaatc atgtttcgaa tcaatacagg agatagattt
      841 ctgcggccaa tgacattttc ttcatactta tatacttcag aatgagcctt ttcataatcc
      901 atgtaattat tgatagcggt agtcgctaaa tcaaaaacta gcattccaat aaaaaataaa
      961 aaagtgttta gccaatgtat ctcatgaaaa aaagcgatag agaataatac ccctaccgca
     1021 aaaggaaata cactagccac ctttgttcgt atttcaacta cttctaaaaa gatttttagt
     1081 gtcatggttc gtactcctta ttttagttca gaacggtcac ccatcgtgta atgggagtcc
     1141 tccgataatt tgaaggtgtc tttgattgga tcggtcacat atactttatc gtcttttgtc
     1201 acgaagatcg cttccgtccc gttattcaat tcgctttcga cgtattccag tccttttttc
     1261 acacccattg aaaagactgc tgtagacaac ccgtcaccat caattgattt atctgttatg
     1321 atcgtgacac ttgcgatatc attgtcgaac ggataacccg tttttggatc aaacaaatga
     1381 tggtattttt tgccatctac ttctaaataa cgctcgtaaa ttccagaggt aactaatgtt
     1441 ttgttccgtt ctttaataga acctaaaaca gatccgcgag ccatgttcgg atcttggatg
     1501 ccgactgtcc agtcttggtt ttcgcctctt gggctgtggc ctaagacata gacattaccg
     1561 cccaagtcaa cgatggcagt ggtcactcct tgttttttca agactttcac tacttcgtcc
     1621 gtaatgtaac ctttggcgat tgcacctaaa tcgatgatca ttcctttttc ttttagataa
     1681 acagtttttt ctttgtcatt tagttcgatc ttatgataat ccactaattt caatgcctga
     1741 tcgatttctt cttgggaagg ttttctggcg tcatcaaaac cgattcgcca taattgtgtg
     1801 attgcaccaa tcgccatatc gaatccgcct tgagaatctt ggctatattc gtaggcccgc
     1861 ttgactaacg tgtagacgtc atcagaaact tttactggtt tgatcccagc ttgctcattc
     1921 acttcatcga tctcagaacc tttttgattg atcgtgattt tatcaccaag ttcttttact
     1981 cgatcgaagg caggtttcaa tgctgattct ttgccttcat catacacacg gatacgaacg
     2041 taagtcccta acaagaactg ttcatcagaa tatggatctt tcaatatctt ggtagctgct
     2101 gaactttcag tggttgtttt atttgctgag ttgctgcagc cagttagcac cataaaagag
     2161 atgcccagtg tgattaagga aaatagtagt tttttccgca tctttttcct ctcttcattt
     2221 tgaaaggtga gacgactgcc taatctggct atcgtcccac cctccaactt ttattagtat
     2281 gattatgtga ttatttttct gttacgatat tatctacttc gattgtttga gtgtcgcctt
     2341 tttcagctgc attcactaat tgttgtgcgt acatgatgaa tgaatgtgag ctgtgtgtag
     2401 cacctgtaac aacttctaca ttagcaggtg agccatcttc ttcgcccatt gctttgacga
     2461 attcgtcgtt cagagtaggg atgtaagttt ttggttctgt accgcttttt gctttcatat
     2521 tttcattata ttctgtatca tcttgttttg atttaccgtc tttgtcgata taatcaaagt
     2581 ttgattcagt tactttgccg ccagcaactg tcatttcgaa ttgcacacgg tagccgttag
     2641 agtagttctt ttcttcaagc ttgtaagtgc cgtctttcaa atcagcacca ttgtcgattt
     2701 cgattgtatc tgtgttacca gcttgagcag cttggatcaa ttgttgtgcg tagttttgga
     2761 agctttcaga tgagtgagta gctccagtta cgacttccac accgcttgcg ctttgtgctt
     2821 ttaagaattg gtcattcaac tcaggaatgt atttttctgg gtttgtgcca gattttgctt
     2881 ccatgttttt gttgtattct gcatcttttg tttttgattc gccgttttca ttgacgttat
     2941 catattttga ttcagtgatt ttgccgtctt ttacaaccat ttcaaagact gcacggtaac
     3001 catttgaata atttttttct tctaatttat atgtgccgtc ttgcaaatct ccgccagcta
     3061 caacttttgc agatgattct gttgtgcttt ttgcagtcga agattgtgct gtagatgatt
     3121 cagaagaaga gtttgagctt ccgttgtcat ctgcgccgca agcgcctaac actagagctg
     3181 aaaatgctaa tacggcaaat ccagttacaa aacgtttttt cttcatttta ataccccacc
     3241 attccatttc tagtccacaa tttttctttg tgattcatta tacattctaa tctttttagc
     3301 ctataagtca actatttttg ataaataacc catgtaatat ttcaaacgtt ttctttcagc
     3361 aaatttcgtg aaaaaacgct ttattttaaa atttgaaaaa aatccaaaag gagttagaca
     3421 aaagaacaga acatctatat aatatatgga gattgtgtaa taagtatcaa actaaaagaa
     3481 ttatcatata ttcattatat agatagtcta taaggagcgg atgatcaatg gcaaagcaaa
     3541 atattgtcgt tgtaggagca ggatatgccg gtgtttcagc tacaaaatac ttggcaaaga
     3601 aactgaaaaa agaagatgta gcaattactc tgatcgatcg tcattcgtac catactatga
     3661 tgaccgagtt gcatgaagta gctggcggac gtgtagaacc agaagcaatc caatacgatc
     3721 tgcagcattt gtttgctcgt caaaagaatg tacaacttgt cacagacact gtaatcggta
     3781 tcgataaaga acgaaaaatc gtcaagacca aattaggttc ctatcctttt gatcagctga
     3841 tccttggaat gggcggagag ccgaatgact ttggtacacc tggtgtcaaa gcacacggat
     3901 tcaccctttg gtcatttgaa gattctgtaa ggattcggga acatattgag aagacagtag
     3961 caaaagctgc attggaacca gatgatgaac tgcgtaaagc catgctgact ttcgttgtct
     4021 gtggttctgg atttaccggt attgaaatga ttggggaact gatcgactgg aaaaatcgcc
     4081 tagccaaaga ttataaatta gatccaaacg aaatcacact gatggtcgta gaggcaatgc
     4141 cgacgatctt gaatatgttg gatcgaaatg atgctgcaaa agctgaacgc tatttgcgta
     4201 agcacaacgt ggaattatta ttgaatgcac caatcgtaga agtggctgct gatcatatca
     4261 aattgaaaga cggacgcaac attccgactc acacactgat ttggacagct ggtgtcaaag
     4321 gaacttctga cgctgctgac tttggattag aatcagcacg cggacagcgg ttgatcgcca
     4381 atgaatatat gcaggcaaaa ggctacgaag ataaaaacat ctatatcatt ggtgatttag
     4441 tcttttatga agaattccca ggaacaccga caccgcagat cgttcaagct gctgaacaaa
     4501 caggacacac agccgcagcg aatatcgtgg cttcgatcaa aggcggagaa aagcataaat
     4561 ttaaaggaaa ctatcaagga tttatggttt ctattggtgc caaatggggg gtagctaacc
     4621 tatttgataa gatccattta agcggatttt tagctatcgt aatgaaacat atcgtgaatt
     4681 tgaaatactt ctttgatatt cgttctggtt attatatgtt ccaatattta atgcatgagt
     4741 ttttccatat caaagatgat cgcaacgtga ctcgaggaca ttcttctcgt tacggcaatg
     4801 tcttatggag tgtgccactt cgtattttct atggtttagt ttggttcgtt gaagcttcca
     4861 aaaaaatcat tgggaatggt gaagtgttca aaccaagtac ttggtttggt gaaggatcat
     4921 ggttcactgg aaacagtgtg ttcccttgga catgggaata caatgtaaca gatgttgcca
     4981 gtggtgcttc tgctgctggt gatgcaacca cagctgccag cggagcaggg gcaagtgccg
     5041 gagaagcagc gactcaagct gcacattttg gtttgagtta tgcatacggt gaagaaccaa
     5101 tggctgtgat tgagaagtca ccagactggt tcacaaagat catgcaagtg atcatgccaa
     5161 acaatgatgt agcaatgttc ttccaaaaat tcatggtatt ctttgaaatt gccttggcat
     5221 tagcattgat tgctggatta ttcacatggc tatgcagtgc gacaacgatt gtattggtga
     5281 tcacgttctg cttatcaggc atgttttact gggtaaacat ttggttcatt tttgttgctt
     5341 tcgcattgat gaacggttcc ggacgtgcga ttgggttgga tcgctgggta attccatggc
     5401 tacaacgtac actaggtaat tggtggtacg gtagaccaag ttcccagtac ggcaagaaat
     5461 aaatagataa agaacgttat ttgaatgcaa gatttcaata gaaaggggct gagacaaacc
     5521 gtcacagcct cctttttatg taaaattaaa ggaataagat gcccgagata agcctccatg
     5581 agcaagacac aggtgtcaca acctctgtta caacctcttg ttataaacgg tgttccagaa
     5641 gtagcttctt cgaaaaataa gccgaaattt cacaaaaact tgaaaagtaa ttttcgtaaa
     5701 ttccttctta tttcttgaag ttgcccactt ctgtcacaac ctcttgttat aaacggtgtt
     5761 ccacctgctg cttctcggta ataagcccaa agaattagaa aacatggaaa gctgttttct
     5821 attcttcgtt cttattactc aaagcaagac acaggtgtca caacctcttg tttttatgct
     5881 aaaattgggt gagttaatct ggaaaaagga gaacaaaaat gagccttaaa gaatttgctg
     5941 aaaaaagtct gctcaaacct tgggatgttt ttattatttt gcttttgact gttctttctt
     6001 ttttaccagt catgattttt ggtcttcagc aaaacaccgc aacagcagaa aaagaagcgg
     6061 tactgcgtgt ggatggcaca gaaatcaaaa cattcccttt gatggctgga gaagagagca
     6121 acacatatac ttacaaagat gaacacggag attataactt gatcgagata gatggcgatc
     6181 gagtacggat aaaagaagca gattgcgatg accagatctg cgtacgtcga ggctgggcaa
     6241 cgaaaaatgg cgaaaccatc gtctgtttgc cacataaatt agtgatcgaa gtccgttcaa
     6301 cagatggagg tgacgaagac agtctgattt attagacctt cacacaccat gagtaaatta
     6361 caaaaaatga tttatatttc gctacttgtt gcacaaggag tgatcattgg tttattggaa
     6421 aatatgatcc cttatccttt ttcttttgcg cctggtgcaa aactaggctt agccaatcta
     6481 atcacgatcg ttgccatttt taccatgaaa aaacaagaca gcttcttact actttggcta
     6541 cgactattcc tgactacttt gctaggcgga acgatttcca cattccttta tagtatgagt
     6601 ggtgctttgc ttagttattt tggaatgtta ttggtcaagc aattaggacc aaaacgtgtc
     6661 agtatcatcg gaattagtgc ggccggcggt ttcatgcata atgtcggaca gcttttgatg
     6721 gcttctttca ttgcacaatc atggacagtc atgttgtact tgccagtcct ttcagtttta
     6781 gggattttat cagggattgc aatcgggatc gcagcgaatt atcttttacg acatgtgcag
     6841 acacttcaac gattccaaaa agattatgag cagggaacca aacaaaaatg gagcccaatg
     6901 tttaccaaaa aataatcgtc acacaaggag tttttttatg aagctacatc caatgtggga
     6961 aaactatcct gctttaagta aagaattgac agaaacacta aaacggatgg aagaaactgt
     7021 ccgcctgaaa aacaaacctg tcgaacaagc catcaaagaa acgatccatg ccggcggaaa
     7081 gctgttgcgt cctgcctatc agctattgtt ctcacaattt ggaccagagc aagatcgaga
     7141 caaagccatc gctttggcag cttctatcga aatgctccat acggccacac tgatccatga
     7201 tgatatcgtt gatgaagcgg atctgcgacg tggtcagcct aatatccgta gtcagtttgg
     7261 taatgtcgtt tctgtctatg caggagacta tttatttgtc tgctgtttta aactattgtc
     7321 tgattactcc acttccttga aaagtctcca attgaattct cgcagtatgg aaaaagtatt
     7381 gaatggcgaa ttagggcaga tggatgatcg ctataattat gaactttctg taaaagaata
     7441 tttggaaaat atttcaggta agacagctga actgttccaa ttaagttgtt ctgttggcgc
     7501 ttttgaaagt ggaacaagcg agcgcttcgc aaaaaaagca ggagatatcg gactttctat
     7561 cgggatggcc tttcagatta tcgatgatat tttagattat acaaaagaga gccaggaaat
     7621 cggcaaacct gtactagaag acatgcgtca aggggtctat tctttaccgt tgatctactc
     7681 tttgcaaaaa aacaaaccaa agctactacc ttatttagag aagaaagcgg caatgacaga
     7741 agaagatgtc gacgccgtac gcaaaatcgt tgaacataca ggaggcgtgg aagaagctag
     7801 gaagttagcg gcctcttaca cagaaaaggc tttgaaggaa ataaagaaat tacctgccac
     7861 ctctcttcga acaaaagaga atctcttttc ccttacccaa ctgattttgg atcgcaaaga
     7921 ctgaataggg aaaggttcga tacgtaaata aatttctcag aaggaaatct acgtgttttt
     7981 tgacaaattg aattgtagtt cttgtattta tgataaaaag caaaaataaa gagcaacgtc
     8041 cgttagcgac gttgctcttt tttatcttga atattttttt accttttcga tttcttataa
     8101 ctcataaaag tgattcttaa accgattaca agtaatataa cgcctgcgag tgttatccaa
     8161 ttattcgatt gacttccagt tttaggaagt gctctttttg atttgtttcc attgtcattg
     8221 cttgttttat tagttaagtt aaagttcgtc ctgttatccg aacttgtttt tgagaaggag
     8281 acacttgcat gacgtgtatc gcttgtggta gacgacgtgt ctgtactatc gcttgaagtt
     8341 gatgaatctg agctatcact tgtggtagag gatgtatctg tactgtcact tgaagctgac
     8401 gtgtccgtgc tatcacttgt ggtagaggta gtatctgtac tgtcacttga agctgacgtg
     8461 tccgtgctat cacttgttgt ggtagatgta tccgtactgt cgcttgaagc tg
//
LOCUS       DAFBVQ010000086         8492 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.089, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000086 DAFBVQ010000000
VERSION     DAFBVQ010000086.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8492)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8492)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8492
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.089"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..173)
                     /locus_tag="LLC22_002529"
     CDS             complement(<1..173)
                     /locus_tag="LLC22_002529"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006735101.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5435750.1"
                     /translation="MATKIADELENHVLETGMQKITTHASITAKPFFEKRGYKVINEQ
                     TVELRGQLFTNFL"
     gene            complement(593..1714)
                     /locus_tag="LLC22_002530"
     CDS             complement(593..1714)
                     /locus_tag="LLC22_002530"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010730282.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS4 family transposase"
                     /protein_id="HBK5435751.1"
                     /translation="MDKYNVKTSFQKWFSAINFSGLSENSQSLISDFDFYSKKLDFQT
                     TLKVLLHAVYEELPSYREIDRAFLDQRLCKELGIDSLCYSSLSRRAPEIKQEVLMEIF
                     TQLVARISAQQPSSKTTSLQLIDSTTIPLNKAWFPWAKFRKTKSGIKLHLNLCYLDKT
                     NQYPESFTMTNASEHDRNHLEVLVDKTQATYVVDRGYFDYKLLDKLNRDGYFFVTRTK
                     SNTKITILDQIEVADTTTRDGTIISDQQVILVGGVNHVTERFRLVTVLTKGQKILRMV
                     TNLFDVSPNEVADMYQARWQIELLFKHLKQNLTIKRLYSHSEQGAINQVILTLIATLL
                     TYVIKIELNTTATLFQLKRTFHYLMFEPAEEWFKRYRPG"
     gene            2042..3451
                     /gene="istA"
                     /locus_tag="LLC22_002531"
     CDS             2042..3451
                     /gene="istA"
                     /locus_tag="LLC22_002531"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321361.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21 family transposase"
                     /protein_id="HBK5435752.1"
                     /translation="MDDIKTIKHLRNNRDQSIDQIRKAMNINWRTAKKYADSDQLFIT
                     DPTRKNKSMMDDGWGEIIGSWLEEDLRLRRKLRRTAKAIHEQLKPLGFPGSYRTVCVY
                     ISQWKKQRYDETNYQAVDRLDHPIGEAQVDFGTMEVMHEDHMKDIQLLIMSFPYSNAT
                     SASAMPAQNQECFLEALKQLFNQCGGVPKTIRIDNLTPAVKKTKSKFEEAQLTDEFLR
                     FTIHYGCDVQVCNPRSGHEKGHVENKVGYVRYNFFSTSPIMDSFESLNKQLEEQLKAD
                     RKRTHYSKHQLIEDLWKKENKALHSLPQEDYPIFKEVEAKLNRYHEMKLDQTVIHIPK
                     AYGYSQLTVVLTWNKFKVLTPHGEILMNEYRPYMNKKRLIPWSDIMKQWSNKLNVVSY
                     SRYWKYLPARLQNYLAIDNNHLKYRRIKQLLSLLATYDIQQINEQFYELVVQEDAPSD
                     FDVNWSNYDALTKTGGVQK"
     gene            3448..4176
                     /gene="istB"
                     /locus_tag="LLC22_002532"
     CDS             3448..4176
                     /gene="istB"
                     /locus_tag="LLC22_002532"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289053.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS21-like element helper ATPase IstB"
                     /protein_id="HBK5435753.1"
                     /translation="MIGQTLEDYCKKLRLSHIITNIPRASFEAPEQFITDLFRLELET
                     RQQIKLERMEKLAKFPVPKSLKNYEWHEDIFLPSHLDKETLVSLDFLKRQENIVCVGS
                     PGTGKTHLAIALGRKACSEGVSTKFFRVNNLVEQLENALKKQQLASFKKRFETTELII
                     LDEMGYLPLTKEGAELLFQLISDWYEQKSIIITSNLEFSQWNRVFMDSRLTAALVDRL
                     IHHAHIISFKGESFRLKNSLSKSY"
     gene            complement(4304..5215)
                     /locus_tag="LLC22_002533"
     CDS             complement(4304..5215)
                     /locus_tag="LLC22_002533"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5435754.1"
                     /translation="MKIKIERSNKEKIPKKKKERVVSVGKHRKMVLALWLLLSCSLAF
                     GIYKNFTAIDQHTTHEKVVVKEKIVNTSGVENFTVDFVKEYFSWKNNKEVIEKRMTNL
                     EQYLTEEGLALSQDMVRADIPTSSEVVSVKILDVEKHSEEFVVSFVVDQKITEGKKTQ
                     SISSAYRLMIFEDEKGNHIVTSLPTMIGKPEKAKHKVRQVKSDSKIDSKTTEEITEFL
                     ETFFRLYPAASEKELEHYVEKDAMQPINTNLKFVELVNPIYKQKGKAIQVIVGVEYLD
                     ELSKTTSVFQYRLKLYKNENWTISNCE"
     gene            complement(5232..6239)
                     /locus_tag="LLC22_002534"
     CDS             complement(5232..6239)
                     /locus_tag="LLC22_002534"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoprotein"
                     /protein_id="HBK5435755.1"
                     /translation="MNLKKLSIISLTFLTISFVGILMCVGLLFGEDGEGSGSSGTSPG
                     GSSVSEVVLKHRSMVEKYAKESDITEYVSILLAIIQVESGGTMEDVMQSSESAGLSPN
                     SLSTEASIKQVCLYFSSLVKCSKELGCDQDSIIQAYNYGDGYLDYVAKNGKKHSFALA
                     ESFSKEKSGGQKVDYPNPIAIKENSGWRYNYGNMFYCLLVKQYLTTTQFDDKTVQGIF
                     DEAFKYEGTAYVFGGSSPGTGFDCSGLTQWCYAKVGLKLPRVAQDQYDAMTHIDLKDA
                     KPGDLIFFHSTYDAGTYVTHVGIYAGENRMFHAGDPVGWTNLTDSYWQQHIIGAGRYK
                     Q"
     gene            complement(6236..8365)
                     /locus_tag="LLC22_002535"
     CDS             complement(6236..8365)
                     /locus_tag="LLC22_002535"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FUSC family protein"
                     /protein_id="HBK5435756.1"
                     /translation="MKKKLFRIVGIVFISIVTLTVLLSLVGTVAEATGLVDDTVEAGN
                     LYSKYSLNNYQLDFFVDSSWDWLPWNWGDGLGKSVMYGLYAITNFIWTVSLYLSNATG
                     YVVQEAYKLDFISDTAKSIGKNIQTLAGITENGLQTSGFYFGFLLLMILALGVYVAYT
                     GLLKRETTKAVRTVINFVMIFLLSGSFIAYAPTYITKINDFSSDVSEAALSLGTKIVV
                     PNSESQGKDSVDLIRDSLFSIQVQQPWLLLQFDDSNIEEIGEGRVNKILSVSPDENKG
                     KDREEAVKAEIEDNDNANLSITKTMNRLGTVVFLVLFNIGISFFVFLLTGIMLFSQIL
                     FIIFAMFLPISFLLSMLPTYESLGKRAIIRLFNTIMMRAGVTLVITTAFSISTMFFNI
                     SATYPFFMVAFLQIVTFAGIYFKLGDIMSMFNLQSNDSQSMGRRVMRKPQMLMNRKLR
                     QLNRNVGRTFAFGGGAAVGGKLATSSTKGKGSSKINRVSNRKNHSARSINELNSDLKK
                     QEQPVGTKKESRINLVGRKVGKVLDTKEIVKDKAKQAKNQVTDAPTNLKYSLHKGMEK
                     TKKVPEDFKRGPFEEKANRGELREKQRQRRDAKMDEKRKVLNEAWNRHEKGRENVPIK
                     KEIKPQKNELPENRSLKPRVQVHSNPEIKRKLSSQEVIPNGSTQPLSKNNSFQQVKQR
                     FTFPKRTNQQVQRKKNTRPKPKPGEKR"
     gene            complement(8370..>8492)
                     /locus_tag="LLC22_002536"
     CDS             complement(8370..>8492)
                     /locus_tag="LLC22_002536"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5435757.1"
                     /translation="NGQCLMQDLYGRVGVVQVHPVFEELFHAFDTRPPVQERME"
BASE COUNT         2599 a         1728 c         1486 g         2679 t
ORIGIN      
        1 attaaaaagt tagtaaataa ttgccctcta agttccacgg tctgttcatt aataacttta
       61 tatcctcgtt tttcaaaaaa tggctttgcg gtaatggaag cgtgggtagt gattttttgc
      121 ataccagttt ctaaaacatg gttttccaat tcatctgcaa ttttagtcgc aatacctttt
      181 ccttgatggc tatgtttttg tcacaacttc agtattcctg taacaatacg gatttcagta
      241 tacaacaaca gcttttgaaa agatacttgc aaaaggatta agatatctat gacctgctat
      301 gctcactgat gttgaaaaga atgttttatt aggattgagg taagcaagat agtgaatatg
      361 tccggaaagc ctgtaaaata aggcttttcg gacatatgtg aagttataaa aagatagcga
      421 aaaatctatt tagtatcact aatgttgcga acatatcgtc agaatagtct gacatttatt
      481 tcttgctaaa aatttcaaaa aagtcaagtg ctgacgcagc ggatgactat tttccagaaa
      541 attttagtat gtattcaaaa atcaaacgtg acaacagcta ttaactacat cctcatccag
      601 gtctgtaacg tttgaaccac tcttctgcgg gctcaaacat taagtaatgg aaggtacgtt
      661 tcaattgaaa cagcgtcgct gtcgtattca actcaatttt tatcacataa gtgagaagcg
      721 ttgcgattaa ggtgaggatg acttgattta tcgccccttg ttcactatgt gaatatagtc
      781 gtttaatggt cagattttgt tttaagtgtt tgaacaacaa ttcaatctgc caacgggctt
      841 gatacatgtc ggccacttcg tttggcgata catcaaagag attggtcacc attcgcagga
      901 ttttttgtcc cttggtaaga accgttacca acctaaaacg ctctgtcaca tggttgacac
      961 cgccgacaag aatcacttgt tggtcactga ttatcgtccc atcacgggtt gttgtatctg
     1021 ctacttcaat ttgatccaag atggtaattt ttgtattaga ttttgtccgt gtaacgaaga
     1081 aatagccgtc acgatttagt ttgtctaaca acttgtaatc aaagtagccg cgatccacca
     1141 catacgttgc ttgcgtttta tcaacaagaa cttcaaggtg attacggtca tgctcactcg
     1201 catttgtcat cgtaaaactt tcaggatact gattggtttt atcaagataa cagagattca
     1261 aatgtagctt gatgccagac tttgttttcc gaaacttggc ccatggaaac catgctttgt
     1321 tcaacggaat agtcgttgaa tcaatcaatt gtagactggt tgtttttgag cttggctgct
     1381 gagcagaaat tctggcgact aattgcgtaa aaatttccat caatacttct tgcttgattt
     1441 ctggcgctct acgagataac gagctgtaac acagggaatc aatgccaagt tccttgcaga
     1501 ggcgctgatc taaaaaggcg cgatcaatct cgcgatagct tggcaattct tcataaaccg
     1561 catgaagtaa cactttaagc gtcgtttgga agtctagttt tttactgtag aaatcaaagt
     1621 cgctaattaa gctttgagag ttttctgata aaccagaaaa atttattgca gaaaaccatt
     1681 tttgaaatga ggtttttacg ttatacttat ccatgcgtga gtccttttta ttggtcttgg
     1741 ataagtcatc cgagaatagt ataaaggact tttttgcgtt tggatagctt tgtattaggc
     1801 ttttgatggg ttaaaaagtc tttgcaacac tagtaattta gtatttatgt ataaattgaa
     1861 agatatttta ccaccactta gtcttcttaa aagtgatcca acattttgtt tgtggcagaa
     1921 tttaactaca cactaatgca gccgaaagta cacaactatg cagcagtttg actgcgaact
     1981 ggtttccttc catcataagt ttgaatgact tagtgatgga ggtacagaaa ggttgttaac
     2041 tttggatgat attaaaacaa taaaacattt gagaaataat cgtgatcagt caattgatca
     2101 gataagaaaa gcaatgaata tcaattggcg aacagcgaaa aaatacgccg atagtgatca
     2161 actattcatt acagatccca ctcgaaaaaa caaatccatg atggatgatg gttggggaga
     2221 aatcatcggt agttggctag aagaagacct acgtttacgc agaaaacttc gtagaacggc
     2281 caaagctatc catgaacaat tgaaaccttt gggtttccct ggctcctatc gaacagtttg
     2341 tgtatacatt tctcaatgga aaaagcagcg ttacgacgaa acgaattacc aagctgtcga
     2401 tcgtcttgat catccgatcg gagaagcaca ggtcgatttt ggaacaatgg aagttatgca
     2461 tgaagatcac atgaaagata tacaacttct tatcatgtca tttccctata gtaatgcgac
     2521 gtccgcaagt gccatgccag ctcaaaacca agagtgtttc ctggaagcat taaaacaact
     2581 atttaatcaa tgcggcggcg ttccaaaaac gatcagaata gataacttaa ctccagcggt
     2641 gaaaaaaaca aaatcaaaat ttgaagaagc acaactaacc gatgaattct tacgtttcac
     2701 cattcattat ggttgtgatg ttcaagtctg taacccacgt agtgggcatg aaaaaggaca
     2761 tgtcgaaaat aaagtgggtt atgtccgata caatttcttc tcgacttcgc caatcatgga
     2821 ctcttttgag tccctaaata agcaacttga agaacaatta aaagcagatc gaaaaaggac
     2881 gcattattca aaacatcaat taatcgaaga tttgtggaag aaagaaaata aagcgttaca
     2941 ttctcttcca caagaggatt acccaatttt taaagaagtg gaagctaaac taaatcgtta
     3001 tcacgaaatg aaattggatc aaacggttat tcatattcct aaagcatatg gctattctca
     3061 attgactgtt gttttgactt ggaataaatt caaagttctt acgcctcatg gagaaatatt
     3121 aatgaacgaa tatcgcccct atatgaacaa aaaaagattg atcccatgga gtgacatcat
     3181 gaaacaatgg agtaataaat tgaatgtcgt tagttattcg aggtattgga agtacttgcc
     3241 tgcacgcctt caaaattatc tagcgattga taataatcac ctgaaataca gacggataaa
     3301 acaattacta agtttattag cgacctacga tatccaacaa attaatgaac aattttacga
     3361 attagtcgtt caagaagacg ccccctctga ctttgatgtg aattggtcaa actatgatgc
     3421 attaacaaaa acaggaggtg tgcaaaaatg attggacaga cgttagaaga ttattgtaaa
     3481 aagcttcgat taagccatat catcacgaac ataccaagag cttctttcga agctccagaa
     3541 caatttatta ccgatttatt ccgtttagaa ctggagacca gacagcagat caaattagaa
     3601 cggatggaaa aattagccaa atttcctgta ccaaaatcgc taaagaacta tgaatggcac
     3661 gaagatattt ttctaccatc tcatctagat aaggagaccc ttgtctctct tgattttcta
     3721 aaaaggcaag aaaacattgt ttgtgttggc tctcctggta cagggaaaac acatctagcg
     3781 atcgcattag ggagaaaagc ctgtagtgaa ggtgtttcaa ccaaattttt ccgagttaac
     3841 aatctcgtag agcaattaga gaatgcatta aaaaaacaac agctagccag tttcaagaag
     3901 cgattcgaaa caacagaatt aattattctt gatgaaatgg ggtacttacc attgacaaaa
     3961 gaaggagctg aacttctctt ccaactgatt tcagattggt atgagcaaaa gagcattatt
     4021 attacctcta atttagaatt cagtcaatgg aatcgagtgt ttatggattc tcgattaaca
     4081 gctgctctcg ttgatcggct aatccatcac gctcacatta tcagcttcaa aggcgaaagt
     4141 ttcagattga aaaattcatt atctaaatca tattgaagga aaaaactagt tgcagcaaaa
     4201 ctctgcactt tcggctgcat ttttttgtaa aaagctattg cacaacacaa acatttgaac
     4261 gacgtaattc caaatgttgg attgctttta gataatcttt tatttattca caattgctaa
     4321 tagtccaatt ttcatttttg tatagtttta atctatactg aaaaacactt gttgttttgg
     4381 acaactcatc aagatactca acaccaacaa tcacttgaat cgctttaccc ttttgtttgt
     4441 aaataggatt cactaattcc acaaatttca aattagtatt aattggttgc atcgcgtctt
     4501 tttcaacata atgctctagt tctttttctg aggctgctgg ataaagcctg aaaaacgtct
     4561 ctaaaaactc ggtgatttct tccgttgtct ttgaatcaat ttttgaatca ctttttactt
     4621 gtcttacttt atgttttgcc ttttctggct taccaatcat agtgggtaaa ctcgttacaa
     4681 tatgattgcc tttttcatct tcaaagatca tcagacgata tgcagaagaa attgattgtg
     4741 tctttttccc ttctgtaatc ttttgatcta ccacaaatga aacgacaaat tcttccgagt
     4801 gtttttcaac atctagaatt tttactgata caacctcgga actagtggga atatccgctc
     4861 gaaccatatc ttggctcaaa gcgagccctt cttctgtaag gtactgctca agattagtca
     4921 ttctcttttc aattacctcc ttgttattct tccatgaaaa atattctttc acaaaatcta
     4981 cagtaaaatt ttctactcca gaggtattca ctattttctc tttcacgacc actttctcat
     5041 gagttgtatg ctgatcaatg gccgtgaagt ttttgtagat tccaaaagca aggctacaag
     5101 acaataaaag ccaaagggca agcaccattt ttcgatgctt gcccacggat actactcgtt
     5161 ctttcttctt ttttggaatc ttttccttgt tacttcgctc aatttttatc ttcattttcc
     5221 attcctcttt tctattgttt ataccgacca gcaccaataa tgtgctgttg ccaatagcta
     5281 tcggtaagat tggtccaacc caccggatct cctgcatgaa acattctgtt ctctcctgca
     5341 taaatgccca catgagtcac ataagtaccg gcatcataag ttgaatgaaa gaaaatcaaa
     5401 tcgcctggtt tggcatcttt taagtcaata tgagtcatag catcatattg atcctgagcc
     5461 acccgaggga gtttcaaacc aactttggca taacaccatt gagttaaacc actacaatca
     5521 aacccagttc cgggacttga cccaccaaat acataagccg ttccttcata cttgaacgcc
     5581 tcgtcaaaaa ttccttggac tgttttatca tcaaactgtg ttgtagttag gtactgcttc
     5641 actaataagc aataaaacat attgccatag ttataccgcc acccactatt ttccttaatc
     5701 gcgatgggat tgggataatc gactttttga ccacccgatt tttcttttga aaaagattcg
     5761 gctaaagcaa aactatgctt ctttccgttt ttcgcgacat aatccaaata cccgtcacca
     5821 tagttataag cctgaatgat actatcttga tcgcatccta gttctttgga acacttaacc
     5881 aaagacgaaa aatagagaca cacttgtttg atggatgcct cggtacttaa tgaattcggt
     5941 gataaacctg ctgattcaga actttgcatg acatcttcca ttgtacctcc agattcgact
     6001 tgaataatcg ccaaaagaat cgaaacatac tctgttatat ctgattcttt ggcatacttt
     6061 tccaccattg aacggtgttt caaaactact tctgagacac tactacctcc aggagaagtt
     6121 ccagaactac cacttccctc accgtcctca ccaaacaaca aacccacaca catcaagatg
     6181 cccacaaaag agatggtcag gaaggttaac gaaataatac tcaatttttt taagttcatc
     6241 ttttctcacc tggctttggt tttgggcgag tgttcttttt tctttgtact tgttgattgg
     6301 ttcgctttgg aaaagtgaat ctctgtttca cttgttgaaa ggaattgttc ttgcttagtg
     6361 gctgagtgct tccgtttgga atgacttctt gactagaaag tttccgtttg atttcaggat
     6421 tcgaatgtac ttgtaccctt ggttttaaag acctattttc tggtagttca tttttctgtg
     6481 gttttatctc cttttttatc ggaacatttt cccttccttt ctcatgacga ttccatgctt
     6541 cgttcaatac tttgcgtttt tcatccattt ttgcgtctct tcgttgtcgt tgtttttctc
     6601 gcaactcccc tcgatttgct ttttcttcga aaggccctcg cttaaagtcc tctggtactt
     6661 ttttcgtctt ttccatgcct ttatgaaggc tgtatttcaa gttagttggt gcatcggtta
     6721 cttgattttt tgcttgtttc gctttgtcct tcacgatttc ttttgtatcg agtacttttc
     6781 caacttttct accaactaaa tttattcgtg attctttctt cgtgcccact ggttgttctt
     6841 gttttttcag atcagaattt agctcgttaa tgcttctcgc ggaatggttc tttctattgg
     6901 acactctatt gatttttgaa ctacctttcc cttttgtaga actggtagct agtttcccac
     6961 caactgctgc accgccacca aaagcaaaag ttcgacccac atttcgatta agctgtcgca
     7021 attttcgatt catcaacatt tgcggtttcc gcatgactcg ccttcccatt gactgactat
     7081 cattactttg aaggttaaac atgctcataa tgtcacctaa tttgaaatag ataccggcaa
     7141 aggtcacaat ttgtagaaaa gctaccataa agaagggata ggtggccgaa atattgaaaa
     7201 acatcgtgga gatactgaat gcagtcgtaa tgactaaggt aactcccgct cgcatcataa
     7261 tcgtattgaa caaacgaata atcgcccttt tgcccaaact ctcatacgtc ggcaacatcg
     7321 acaataagaa actaatgggc agaaacatcg caaagataat gaaaaggatt tgtgagaaca
     7381 acataatccc tgtcagaaga aacacaaaaa aggaaatccc aatattaaac aacactaaaa
     7441 agaccacggt tcctaaacgg ttcatggtct tggtaatact gagattcgca ttgtcattat
     7501 cttcaatctc tgctttgact gcttcttccc gatccttacc cttattttca tccggactca
     7561 cggataaaat cttattaacc cgaccctcgc caatttcttc tatattggaa tcatcgaatt
     7621 gtaatagtaa ccagggttgt tgaacttgaa tcgaaaataa actgtctcga atcaaatcca
     7681 cactatcttt tccctggctt tctgaattag gtacaacaat cttggttcca aggctaagag
     7741 ccgcttcact aacgtctgag ctaaagtcat tgatttttgt aatataggtg ggcgcatacg
     7801 caatgaaaga acccgagagt agaaaaatca tcacaaaatt aatgacggtt cggactgctt
     7861 tggtagtttc tcgttttaat aatccggtat acgccacata aactcctaga gctaaaatca
     7921 tcaataatag gaacccaaag tagaatcccg aagtctgtaa tccattttca gtgataccgg
     7981 ctaaagtttg gatattcttt ccaatacttt tagccgtatc cgaaatgaaa tccaacttgt
     8041 aagcttcttg aaccacatag cccgtggcgt ttgataaata cagacttact gtccaaataa
     8101 aattggtaat ggcataaaga ccatacatca cgcttttccc taagccatcc ccccaattcc
     8161 aaggtaacca atcccaagaa ctatccacaa agaaatccag ttgataattg ttcagagaat
     8221 atttggaata aaggtttccg gcttcaactg tatcatcaac cagacctgtc gcctcagcta
     8281 ccgtaccgac taaactcaat agaactgtca gagtgacgat gctaataaaa acgattccca
     8341 caatccgaaa aagtttcttt ttcatcccct cactccattc tctcttgaac cggcggacga
     8401 gtgtcaaaag catggaagag ttcttcaaag actggatgaa cttgaaccac acctactcgc
     8461 ccatacaagt cttgcatcaa gcattgaccg tt
//
LOCUS       DAFBVQ010000087         8290 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.090, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000087 DAFBVQ010000000
VERSION     DAFBVQ010000087.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.090"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(45..1511)
                     /locus_tag="LLC22_002537"
     CDS             complement(45..1511)
                     /locus_tag="LLC22_002537"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288052.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide MFS transporter"
                     /protein_id="HBK5435758.1"
                     /translation="MEKQQDKGFFGQPKGLSTLFFTEMWERFSYYGMRALLIYYMYDT
                     VANGGLGLPRATALAIMSIYGSLIYMSSIVGGWVSDRVLGAKRTVFFGGVFIMLGHIV
                     LALPFGVSTLFVSMALIIIGTAFLKPNVSGMVGHLYSKTDLRRDAGFSIFYMGVNLGA
                     LLAPLIVGTIGQEYNYHLGFSLAAIGMFFGLLQYIIQGRKTLDGVGTTPPNPLTTEER
                     KGFIRNLIIALVVIAAVFGGAQLTGHLTIDFFVNTISVLGIILPLYYFIKMLTSKDVT
                     AEEKPRVWAYIPLFLAAIIFWSLQEQGSSILALFASERTQSTLFGVTIQASWYQSLNP
                     IFIFILTPVFVTMWTKLGERQPSTVVKFSLGLLFAGLSYLLLMLPGMLYGTSGKVSPL
                     WLLGSFFIVVIAELCLSPVGLSVTTKLAPRAFESQTIAIWFLADASSQAINAQIARFY
                     TPGTESAYFGIIGAVAIVGGILLFTVKEPIKKLMGSIH"
     gene            1898..2494
                     /locus_tag="LLC22_002538"
     CDS             1898..2494
                     /locus_tag="LLC22_002538"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288054.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK5435759.1"
                     /translation="MTTFTDTLKNRRSIYHLGRNVSLSNEELTTLIKEAIKESPTAFN
                     AQSTRAVILFGDAHEKLWEITEEALRPLTPAEAFPNTQNKLAGFKNGYGTVLFFKDTD
                     VVKGLQEQFELYADNFPDWSEQSNGIATANTWVALVDKGLGANLQHYNPVIDEAVAKE
                     WNIPSNWKLRSQLVFGSPETPAGEKEYMNDADRFRVFG"
     gene            complement(2552..3034)
                     /locus_tag="LLC22_002539"
     CDS             complement(2552..3034)
                     /locus_tag="LLC22_002539"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292941.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435760.1"
                     /translation="MVTFFTVLLFLFVVVMFLFLWLVRKEIIYRTVRNRWVYLVIPFL
                     VSLVIWYTLISHPTADELAKGILSAMIFISFLLDSRGITEEGLVLNSFDKKGVPFSEI
                     NKIVLYQPKGSKIVKMNFFRNGWRGPMLKFSASLEELVPFLSQRLNDEAEIDIMIDPE
                     "
     gene            complement(3140..3337)
                     /locus_tag="LLC22_002540"
     CDS             complement(3140..3337)
                     /locus_tag="LLC22_002540"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435761.1"
                     /translation="MTEEMINLGEQYACKPIGFTKTVIGEVVSKMTNCAVVKVAQCAA
                     EDQELLDEKASMVVAKYDTFE"
     gene            3632..4390
                     /locus_tag="LLC22_002541"
     CDS             3632..4390
                     /locus_tag="LLC22_002541"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631789.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="C39 family peptidase"
                     /protein_id="HBK5435762.1"
                     /translation="MKKKTFKKLLFLGGTAALLLSGTSYYLHIHSPEHTMNTAQKSST
                     QKTKKTKEKAEVLLDVPLESQFDSPSLENGCEVTSLSMLLSFYGYETTKNQLAEQLDY
                     VPVFNADGTHGDPNEGFVGDISGGDWAMVVYVPPVASLAQQIVQTDYHTFPKTDAQLD
                     DIKKALSKGNPVWTSVTINFEVPDETDFMTWTTNNGEVRVTPLVHACVVTGYDKENIY
                     VNDPYGVKNRAVPINDFSAIFTAMGGQMLTLEKS"
     gene            4450..4878
                     /locus_tag="LLC22_002542"
     CDS             4450..4878
                     /locus_tag="LLC22_002542"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435763.1"
                     /translation="MEKFTHKKMDPNEIPIIFVRDCKGNVQGKVSINEWNERRRPATL
                     NELEIKLYRQSLVYYADQEYEKATDLLKFLIARTEYTRFEYIERLANIYHIMNEPVKE
                     YQLLDTVLSVAELIALPAGLEKKLVRRLLRVKQQLSDQEK"
     gene            4924..4996
                     /locus_tag="LLC22_002543"
     tRNA            4924..4996
                     /locus_tag="LLC22_002543"
                     /product="tRNA-Gln"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:4957..4959,aa:Gln,seq:ctg)
     gene            complement(5146..5517)
                     /locus_tag="LLC22_002544"
     CDS             complement(5146..5517)
                     /locus_tag="LLC22_002544"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002329142.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YxeA family protein"
                     /protein_id="HBK5435764.1"
                     /translation="MKVIKYLIGLAAISGILLFGLKYYTEGSYGEIPGILDQLNPLVE
                     KGEVYVKTQKPEEVNEYGTARYVQKAADANGKERTVEFNGLSVLKENHYLKISNKGAH
                     IETYEEVPREKVPEKALAIIG"
     gene            5732..5917
                     /locus_tag="LLC22_002545"
     CDS             5732..5917
                     /locus_tag="LLC22_002545"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288064.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435765.1"
                     /translation="MNQEELFQKVKEMIKNGNFDGAKRFIEEHKEQLGPYKEKAQNLL
                     KDVNIDSVKNKFKNLFK"
     gene            complement(6000..6188)
                     /locus_tag="LLC22_002546"
     CDS             complement(6000..6188)
                     /locus_tag="LLC22_002546"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435766.1"
                     /translation="MNPYEQLIQDLIDGKIEKIDVKREELMAFREAWLKLENRKYVVG
                     KASLNGNVTYHYDPTRLF"
     gene            complement(6212..6475)
                     /locus_tag="LLC22_002547"
     CDS             complement(6212..6475)
                     /locus_tag="LLC22_002547"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435767.1"
                     /translation="MDHVVLEIDLHLINNIRVIYYVVSNSVEQRVLTNKINGILAKKD
                     VHRFNNGEGSYYSIPVEKIIYTTVKVREDLDTKKAYEPIFTTY"
     gene            6633..6890
                     /locus_tag="LLC22_002548"
     CDS             6633..6890
                     /locus_tag="LLC22_002548"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glucose uptake protein"
                     /protein_id="HBK5435768.1"
                     /translation="MIAIGQFVFYIPFFIMISILFYYIKWTKKKFSVLLASLPAVYFT
                     YQIFSFRHWETTSVLITHIIELTLSVIFLIIWIYFLYKNQN"
     gene            complement(6961..7152)
                     /locus_tag="LLC22_002549"
     CDS             complement(6961..7152)
                     /locus_tag="LLC22_002549"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344183.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435769.1"
                     /translation="MEAGKVLQEVKALCADKKYEEAKSLIEKNKENLEEKYPIAQEFI
                     ELKQGTILHRFKHFFGITE"
     gene            complement(7293..7613)
                     /locus_tag="LLC22_002550"
     CDS             complement(7293..7613)
                     /locus_tag="LLC22_002550"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435770.1"
                     /translation="MVRPQEVRAPKEKIEILAIIEDGTQTKKGYSIALVKWKGKKGVA
                     LRWDGDNQQDKGFPVTANGYHPAWFVLPDKFMELYSYDYARAAASIKALDKLTEEQNE
                     MEEK"
     gene            complement(7636..8070)
                     /locus_tag="LLC22_002551"
     CDS             complement(7636..8070)
                     /locus_tag="LLC22_002551"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="universal stress protein"
                     /protein_id="HBK5435771.1"
                     /translation="MSKRYQNIMVAVDGSRQSIKAFAEALDLAKDNEAHLFIVSIINK
                     VELTHSAYAFSKIYADEKQRTEVAMLKKINDAKEYGIAEIHAIVETGDPRNLIANVIP
                     GQENIDLIVMGATGKGAIQQALVGSTASYVVSHAPCSVLVVK"
BASE COUNT         2628 a         1635 c         1314 g         2713 t
ORIGIN      
        1 aggaactgct gcaaataagc aattcctgtt tttatgttca ttgattaatg aatagagccc
       61 attagttttt tgattggttc tttcacagta aatagcaaga taccaccgac gattgctact
      121 gcaccgataa taccgaagta agcagattct gttcccggtg tgtagaagcg tgcaatttgt
      181 gcattgattg cttgtgaaga agcatcagct aagaaccaaa tagcgattgt ttgtgattca
      241 aatgctcgtg gtgctaattt tgttgtcaca gacaaaccaa ctggtgaaag acacaattca
      301 gcaataacca cgatgaagaa acttcccaac aaccacaatg gacttacttt tccacttgta
      361 ccataaagca tacccggcaa catcaatagc aagtacgata atcctgcaaa taaaagtcca
      421 agagagaatt tcactactgt agatggttga cgttcaccaa gtttcgtcca catcgttacg
      481 aatactggtg tcagaataaa gatgaaaatt ggattcaatg attgatacca gcttgcttgg
      541 atcgttacac caaatagcgt agattgtgta cgttcactag caaataaagc taagatagat
      601 gaaccttgtt cttgtaatga ccagaaaatg attgctgcaa ggaataatgg gatataagcc
      661 catactcttg gtttttcttc agcagttaca tcttttgaag tcagcatttt gataaagtaa
      721 tacaacggta agataatccc caatacactg attgtattga caaaaaagtc aattgtcaga
      781 tgaccagtta gttgtgcccc gccgaatact gcagcgataa caacaagtgc gatgatcaag
      841 ttacggatga atcctttacg ttcttcagtt gtcaaaggat tcggcggtgt tgtacccact
      901 ccgtctaatg tcttgcgtcc ttggatgatg tattgtaata atccaaagaa catcccaata
      961 gcagctaaag agaaccctaa atgatagtta tattcttgac cgattgtacc aacgattagt
     1021 ggtgctaata atgcccctaa gttgacaccc atgtaaaaaa tcgaaaatcc tgcatctctt
     1081 cgcaagtcag tctttgaata aagatgtccg accatgccag aaacatttgg tttcaaaaag
     1141 gcggttccga taataatcaa tgccatcgaa acaaacaatg tacttacacc aaatggtaaa
     1201 gccaagacga tgtggccaag cataatgaaa actccaccga agaatacagt gcgttttgct
     1261 cctaacactc ggtcagatac ccatccgccg acgatactag acatgtagat caaagatccg
     1321 tagatcgaca tgatagctaa tgctgttgct cgtggtaatc caagtccccc gttggcaact
     1381 gtatcgtaca tataatagat aagtaatgca cgcataccgt aataactaaa tcgttcccac
     1441 atctcagtga agaacaaagt tgacaatccc ttcggctgcc cgaagaagcc cttgtcttgc
     1501 tgtttttcca taatctatac cccaattctt taaattttca gaaaatatta tacatcttta
     1561 ccgaaaaatt taactaaaaa acttatttaa gaaatataaa ctaattttct ataaaagcaa
     1621 gtaattttta atggcaatat cataaaaaaa agaagataga gatttaataa ttatatatca
     1681 gctgtttttt tcaaataagc aaaaattcct aaaacacaac aatgaaagcg ataactaaga
     1741 aaatccttac ataacgattt ttcttattaa aattgttttt tgaacttcgc ttattttttg
     1801 tgagcatatc tgtttactta ctttttgtaa ggtgctatac ttcatttcgt aatcaattaa
     1861 aaaaatgcaa aacgcaaatc aaaggagaaa ttttattatg acaactttta ctgacacttt
     1921 gaaaaaccgc cgttcaatct atcatctagg acgtaatgtt tcactttcta atgaagaatt
     1981 aacaactttg atcaaagaag caattaaaga aagcccaact gctttcaatg ctcaatcaac
     2041 acgcgcagtt atccttttcg gagatgcaca tgaaaaactt tgggaaatca ctgaagaagc
     2101 acttcgccca ttgactccag cagaagcttt cccaaataca caaaacaaat tagctggttt
     2161 caaaaatggt tatggtacag tattattctt caaagatact gacgtggtaa aaggtctaca
     2221 agaacaattt gaattatatg cagacaactt cccagattgg tcagaacaat caaacggaat
     2281 cgcaacagct aatacttggg tagcattagt tgataaagga ttgggcgcaa acttgcaaca
     2341 ttacaaccca gttattgacg aagcagttgc aaaagaatgg aatatccctt caaactggaa
     2401 actacgttcg caattagtat tcggttcacc agaaacaccg gctggggaaa aagaatacat
     2461 gaacgatgcc gatcgcttcc gcgtatttgg ataattttat ttgaaataaa aaacagaggt
     2521 tgtgacaaac atcttgtcgc aacctctgtt tttattctgg atcaatcata atatcaatct
     2581 ctgcctcatc gtttaagcgt tgggacaaaa atggaactaa ttcttctaat gatgcagaaa
     2641 atttcagcat cggtcctcgc catccgtttc ggaaaaaatt catttttacg attttagaac
     2701 cttttggctg atataataca attttattga tctcagaaaa aggaacacct tttttgtcaa
     2761 agctattcaa aacaagtcct tcttctgtga ttcctctact gtccaacaaa aaactaataa
     2821 aaatcattgc tgacaagatc ccttttgcca attcatctgc tgtaggatga ctgatgagtg
     2881 tataccaaat gactagtgac actaagaagg gtatcaccaa gtagacccat cgatttcgca
     2941 cagtccgata aataatttct tttcgaacca gccaaagaaa taaaaacatc acaacaacga
     3001 ataaaaacaa tagaaccgta aagaatgtta ccatgacaac tcgcctcgct ttttcttctc
     3061 cagaaaatag gaaaagaata ctgatttacc ttctcaaaga aattggactt gcagcacgcc
     3121 gcacgtccaa ttgttttctt tattcaaatg tatcatattt tgcaacaacc atgcttgctt
     3181 tttcatctaa taattcttgg tcctctgcag cacattgggc aactttgacc acggcgcagt
     3241 ttgtcatttt tgatacaact tcaccaatga ccgtttttgt aaaaccaatt ggtttgcatg
     3301 catattgttc tcctaaatta atcatttctt ccgtcatcaa aatcctccta aactgctgga
     3361 acttttctcc acattaccac tgctatttct ttggagattt aactcattga tttttattta
     3421 cagttaaaaa tcaaccttac aggcattata gcgtactgtt ttcgttttca caattaaaac
     3481 agctgttgta tttagaagaa tttttttcaa aaaattaaaa catattcctt aaaaactaat
     3541 tatttcctac atattaaaat ataatacttc catttccaat aaaaatacat ttataatagg
     3601 aaagataaac agctgaaaag ggagatttca aatgaagaaa aaaacgttca aaaaactatt
     3661 gtttctaggg ggcacagctg ctcttttatt aagcggtaca agttattacc tacatatcca
     3721 ttctccagaa catacaatga acactgcaca aaaaagttca acacaaaaaa cgaaaaagac
     3781 aaaagagaaa gcagaagttt tactagatgt tccattagag agccagtttg attctccttc
     3841 tttagaaaat ggctgtgaag tcacttcgct ttctatgctt ttatcttttt atggttatga
     3901 aacaactaaa aaccagttag ctgagcaatt ggattacgtc cctgttttca atgcagatgg
     3961 gactcatggc gatcctaatg aaggatttgt tggtgatatc agtggcggag actgggctat
     4021 ggtcgtctat gttcccccag ttgcctccct tgctcagcaa atcgtccaaa cggattatca
     4081 cacttttcca aaaaccgatg ctcaactcga tgatatcaaa aaagcactat ctaaaggaaa
     4141 tcctgtctgg acttctgtga ctatcaattt tgaagtccca gatgaaactg attttatgac
     4201 ttggaccaca aataatggag aagtaagagt cactcctctt gttcatgctt gtgtagtcac
     4261 tggatatgac aaagaaaata tttatgtcaa cgatccctat ggtgtaaaaa atcgagcagt
     4321 accgatcaac gatttttcgg cgattttcac tgcaatgggt ggacagatgc taactttgga
     4381 gaaaagctag taattcaaac aaaaatccct tatactcaag ataccaaacc tttgaaggga
     4441 gcgtagataa tggaaaaatt cacacataaa aaaatggatc caaatgaaat tccgattatt
     4501 tttgtccgtg actgcaaggg aaatgttcaa ggtaaagtct ctattaatga gtggaacgag
     4561 cgtcgcagac ctgctaccct caatgaactg gaaatcaaat tgtatcgtca atctcttgtt
     4621 tattacgcag atcaagagta cgagaaagcc accgatttat tgaaatttct aattgctcga
     4681 acagagtata ctcgctttga atatattgaa cgtttagcaa acatctatca tattatgaat
     4741 gaacctgtca aagaatatca gttattggac accgtcttgt cagtagcaga actgattgcc
     4801 cttcctgctg gattagaaaa gaaactagta cgccgccttt tacgagtaaa gcaacaacta
     4861 tccgatcaag aaaaataact tgcgtttttt taggaaagtg ctatgattat tttgttgaat
     4921 aaatgggatg tagccaaact ggtaaggcac ttgactctga atcaagcaat tgtaggttcg
     4981 aaccctgcca tcccaatttg atgtgcttgc tgaaaaaatg aaccccctgt aaaagaacaa
     5041 tctttttgca gggggattat tgtattattt ttactacttg tatttagttt acataattaa
     5101 attatgaata ataaaatcgg gcgtattctt aatacaaaaa ctgatttacc caataattgc
     5161 taatgctttc tccggaactt tttctctagg aacttcctca tacgtttcta tgtgtgctcc
     5221 tttattgcta attttcaaat aatgattttc ttttaacaca gaaagaccat taaattcaac
     5281 cgttcgttct ttcccattgg catcagcagc tttctgcaca taccttgctg taccatattc
     5341 atttacttcc tctggttttt gtgtctttac atagacctct cctttttcaa ctaatggatt
     5401 tagctgatca agtataccag ggatttctcc ataacttcct tcagtataat atttcagtcc
     5461 aaatagcaaa ataccactaa tcgccgccag tccaatcaaa tatttaatca ctttcatctt
     5521 tctacctcct tgttatatat tcagtatatg ggtcagttaa agaaattcca tccgtcccaa
     5581 gttggagatt tttctcctac tttagaagcg agaatcgagt gtttttttag taaaaatgat
     5641 cgttatttga tattattgac gtgtggataa atcagttttt ctcgttttgt ccatgtaaaa
     5701 aatcatgttg atagcaaagg atgtgttcaa aatgaatcaa gaagaattat ttcaaaaagt
     5761 caaggaaatg attaagaacg gcaatttcga tggcgcaaaa cgatttatcg aagaacataa
     5821 agaacaatta ggaccttata aagagaaagc ccaaaatctt ttaaaagatg taaatatcga
     5881 cagtgtcaaa aacaaattta aaaatctatt caaataagta aaactttcac ttttgtaaaa
     5941 tcaaaggagg acaatgctgc tgcatcgtcc tcctttggtt cttttctgaa tacttcatac
     6001 taaaataaac gtgtcggatc gtaatgataa gtcacattgc cgttcagtga ggcttttccc
     6061 accacatatt tacgattctc caacttcagc cacgcttctc gaaaagccat taattcttct
     6121 ctttttacat caatcttttc gatttttcca tcgatcaaat cttgaataag ttgttcatat
     6181 ggattcattt ttttcctcca tctgctgtca atcaataagt tgtaaaaata ggttcatatg
     6241 cttttttggt atctagatct tctctgactt tgactgtcgt ataaataatt ttttctactg
     6301 ggatactata ataacttcct tcaccattat tgaatcggtg aacgtctttc tttgctaaaa
     6361 taccatttat tttattcgtc agtacacgtt gttcgacact gttacttaca acatagtaaa
     6421 tcacccgaat attattgatc aaatgcaaat cgatttctaa cactacatga tccatgaaaa
     6481 tcccactcct tctttcactt tgattatagc aagtttctcc tctaatttca aaatcgatac
     6541 agattttacc ggataaatcc acaaaactgc ttgcgccatt tcgcacaaag tgttattttg
     6601 tatcatggac tttatttatc ggaggcaata gtatgatcgc gatcggtcaa tttgtttttt
     6661 atattccttt ttttattatg ataagcattc ttttctatta cataaaatgg acaaaaaaga
     6721 agttttcagt tttactggcc tctttacctg ctgtatattt tacttatcaa attttttctt
     6781 ttaggcattg ggaaacaacg tctgtattaa taacacacat catcgaattg acgctttcag
     6841 taatttttct tattatttgg atctattttt tatataagaa tcagaattga atccctcgca
     6901 tgtttaaaaa gaaaacgatt aaagatgcag caaatttctg ccgatcttta atcgtttttt
     6961 ctattctgtt ataccaaaaa aatgtttgaa tcggtgaagg atcgttcctt gttttaattc
     7021 tataaattct tgtgcgatcg ggtacttttc ttccaaattt tctttgttct tttcgatcag
     7081 gcttttcgct tcttcatatt ttttatctgc acatagtgct tttacttcct gtaatacttt
     7141 tcctgcttcc atttgcctca ccctcttgcc attttattgc tttaagtttt atttaagtta
     7201 tacgcattat tctagtttca tcccaaataa ccttttttca tttttactcc tcgaactaat
     7261 cagttttcta aaggctgatt ggttcgtctt ttttattttt cctccatttc attctgctct
     7321 tctgttaatt tatctaatgc tttgattgat gctgcggctc ttgcataatc atagctgtat
     7381 aattccataa atttatcagg cagaacaaac cacgctggat gataaccgtt agctgtgaca
     7441 gggaatcctt tatcttgttg gttatctcca tcccatctca gagcaacacc tttttttcct
     7501 ttccacttta ctaaagcgat cgagtatccc ttctttgttt gtgtgccgtc ttcaataatt
     7561 gctaaaattt ctattttttc ttttggcgca cggacttctt gaggacgaac cattttctat
     7621 tcctccctta tctcattact tcacgaccaa cacactgcaa ggggcatgtg atacgacata
     7681 agaagcggtc gatccaacta atgcttgttg tatagcacct tttcctgtcg ctcccataac
     7741 gatcaaatca atattttctt gtccagggat gacattggca atcaaatttc ttggatctcc
     7801 agtttcaact attgcgtgga tctcagcaat gccgtactct ttggcatcat tgattttttt
     7861 cagcatggct acttctgttc tttgtttttc atctgcatag atttttgaaa aggcataggc
     7921 actatgggtc agctcaactt tgttgatgat tgacacgata aataagtggg cttcattgtc
     7981 ctttgctaag tcaagggctt cagcgaacgc tttgatcgat tgtcttgatc cgtcaactgc
     8041 taccatgatg ttctggtatc ttttactcat tggaaccgcc tcctttttct tttattgtaa
     8101 catctcaagc aaaaatacaa aaaatatacg caatatgtaa ataaaatgat gaacaaaagc
     8161 aatttctttc aagttattta tacatttctt ttctcatcag aacacctgtt ctaatcccat
     8221 tatttctgca ttatgtgaaa ttcctcatca tttttcacat cgagcgaaca tcattctgtt
     8281 acaaaaaacg
//
LOCUS       DAFBVQ010000088         8244 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.091, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000088 DAFBVQ010000000
VERSION     DAFBVQ010000088.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 8244)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8244)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..8244
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.091"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(367..1158)
                     /gene="msrA"
                     /locus_tag="LLC22_002552"
     CDS             complement(367..1158)
                     /gene="msrA"
                     /locus_tag="LLC22_002552"
                     /EC_number="1.8.4.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631205.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptide-methionine (S)-S-oxide reductase MsrA"
                     /protein_id="HBK5435772.1"
                     /translation="MLDVEQMEIDLYNIILNRNTREWERTQFEEAKEDLAKMSIKQVI
                     EKLEVNLRPLALRDNLTPDAMDFYLRITGESASAKAYDYAKHKITSPLYQERAIFAGG
                     CFWCMVEPFETKPGVISVLSGYTGGETKKPNYDQVSGGYTGHVEAVEIIFDTRQITYE
                     ELLEIYWQISDPTDAFGQFQDRGKQYRSILFVVNEKQRQLAEKSREQLIQSNRFSRPI
                     VTEIRQAKTFWPAENHHQQFYQKQPKRYKKIKHSHQLHLFFQRHR"
     gene            complement(1349..1984)
                     /locus_tag="LLC22_002553"
     CDS             complement(1349..1984)
                     /locus_tag="LLC22_002553"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331196.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF998 domain-containing protein"
                     /protein_id="HBK5435773.1"
                     /translation="MIFLQKYGFYFLLLGVISDLSTPYILGLFYPKLNQMTTVISVFG
                     DVDSPVRRAFLVWSVVSGLFFVLSLPALYHLFIGTSKTLAILAVATVGLYGIGDCIFT
                     GLFSINTNESSWNLSTWIHNIGSGLGYAGFLLFPLLLVLLYRQSGQGTLSHFYLVLTV
                     ISLLIAGLYRLARIPSISQFAFFKQLGFFQRLSFFFNYLPMICLSFFQLRK"
     gene            complement(2250..3302)
                     /locus_tag="LLC22_002554"
     CDS             complement(2250..3302)
                     /locus_tag="LLC22_002554"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853127.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5435774.1"
                     /translation="METSQKISPKIFLNKVLAGTATGIIIGLIPNAVLGAILKYFSAY
                     PFAVTIAQLAVIFQLATPLIIGGLIALQFGFDPMRMMVVAGASFVGSGVVKFTPDLGE
                     TGVYVGAGTGDIINTMLTASIAVGLILLIGNSFGSVSIVLTPIVVGVGAGLLGFYLFP
                     FVTAITSAIGSLINNFTTLQPLLMSILIGCSFAFLIISPISTVAIGMAIQLDGVSAGA
                     AAMGVAATTFVLVVNSWKVNKSGVTIAIALGAMKMMMPNLFRKPVILIPCLVSAVITA
                     IPVALFSISGTPASAGFGVVGLVGPLASLDAGLNGFLVVLCWLVIPVFAALITQFLCE
                     KVFKLYDREEVFKFLG"
     gene            complement(3315..4253)
                     /locus_tag="LLC22_002555"
     CDS             complement(3315..4253)
                     /locus_tag="LLC22_002555"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_015081805.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBK5435775.1"
                     /translation="MKIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGL
                     QANFNGKEVEAKLPIVLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLC
                     LLNGIGHEDIIEKFVPMENIYIGNTMWTAGLEGPGQVKLFGSGSVELQNLGDGKEAAA
                     KKLADKLSESGLNAHFSDNIHYSIYRKACVNGTMNGLCTILDVNMAELGKTSTAHKMV
                     ATIVNEFAKVAAVEKIELDVPEVIAHCESCFDPETIGLHYPSMYQDLIKNHRLTEIDY
                     INGAISRKGKKYGVATPYCDFLTELVHAKEDSLNVK"
     gene            complement(4704..5354)
                     /locus_tag="LLC22_002556"
     CDS             complement(4704..5354)
                     /locus_tag="LLC22_002556"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435776.1"
                     /translation="MNDEYKNDEDKMLFEEIENRCRLNFELRGKMSLIQQKKYLANKS
                     EFTLGHVEKLISDWISSRSEFTKIKQPIKFDMKKLLLNKSEIGNRDQYIRAKGQEIID
                     SLGEMRSYNYLYVTHRADGMVITVGKSSSNDIFLDGDLFYQLNTNHLSGTENIILRTE
                     YGNEIFAKYDEILKNYLDWAWIIPVESGDAKKLERLLGDELINKKVPILNYYSHRQ"
     gene            complement(5454..5963)
                     /locus_tag="LLC22_002557"
     CDS             complement(5454..5963)
                     /locus_tag="LLC22_002557"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343721.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1456 family protein"
                     /protein_id="HBK5435777.1"
                     /translation="MNNNDRLLRLRYAIDLKDTDLIKAFELGGVPLTKEEAQAVLTKV
                     QDKNKDNAENNVYEKTINNQVFDAFLNGLILLARGPQKDKPIVDTPQKSKEIKYINNV
                     LLKKLKIALSMTTDDILDVFAEAEIYPSKGEIGAFLRKEGQRNFKPCGDKYMRNFLKG
                     LGIYNRRKV"
     gene            complement(6048..6527)
                     /gene="rlmH"
                     /locus_tag="LLC22_002558"
     CDS             complement(6048..6527)
                     /gene="rlmH"
                     /locus_tag="LLC22_002558"
                     /EC_number="2.1.1.177"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722872.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA
                     (pseudouridine(1915)-N(3))-methyltransferase RlmH"
                     /protein_id="HBK5435778.1"
                     /translation="MNIKIISVGKLKEKYLIQGINEYVKRLNAYAKIELIEVPDEKAP
                     ENLSEAQMRQVKEKEGERILAKIKEQEYVYALAIEGKNPTSESFAKQIDQLGIQGKSH
                     LVFVIGGSLGLSEAVMKRSNAQISFGKMTYPHQLMRLILVEQIYRAFRINAGAPYHK"
     gene            6955..8244
                     /locus_tag="LLC22_002559"
     CDS             6955..8244
                     /locus_tag="LLC22_002559"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628497.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trypsin-like peptidase domain-containing
                     protein"
                     /protein_id="HBK5435779.1"
                     /translation="MDRKNVTPKMKKSKNNSLWRKLGLGLVGGIVGGLLTAGIFYAAM
                     GTGNNSSTATSGNQNSAGETVVENIKVNVDSDITKAVDKVQDAVVSVINLQSQNQSSG
                     FGGLFGQQEESSSSDDSNLEAYSEGSGVIYKKDGNTAYVVTNNHVVDGQQGLEVLMKD
                     GTKVKAELVGTDAYSDLAVLKINSDKVETVASFGDSSALKVGEPAIAIGSPLGSEYAN
                     SVTSGIISSLNRQVTSTNESNETVNINAIQTDAAINPGNSGGPLVNIEGQVIGINSSK
                     IASTSESTSNVSVEGMGFAIPSNDVVNIINQLEKDGKVTRPALGITMVDLSAVSTQQQ
                     EQILKIPSSVTNGVIVTNVQTATPAEKAGLKQYDVITKIDDKEVSSGVELQSALYKKK
                     VGDSVKITYYEGSKEKTTTVELTIDQSALKQNQNSEN"
BASE COUNT         2614 a         1674 c         1319 g         2637 t
ORIGIN      
        1 tatagttatt gtttgcgctt ttatacggaa tttagttcat cattaatgtg gaattcgatt
       61 aggtgtctat taattatcaa gatgattctc tacaaaattc catagaaaaa tcaagattct
      121 acaattcgaa ttctctttca catggaaata aaggctagta aaaaaacagg agttgtgaca
      181 aaagacttgt catacctcct gtttccttgc gacttgaagc tgaatgcttt gcgccacaac
      241 cttttcctcg gtgttctcaa agcaactcct cgaaataatt cataactgtc caaaaatatg
      301 aaaagctatt tttgtcagtt gctcattatt ttgtcggagc tgaacgcttt gcgccacaac
      361 cttcctctat ctatgtcgct gaaaaaataa atgaagctga tgcgaatgct tgatcttttt
      421 atatctttta ggttgcttct gataaaattg ttgatgatga ttttcagctg gccaaaaagt
      481 ctttgcttgg cgaatctctg taacgatagg acggctaaat cggttagatt gaatcagttg
      541 ttctcttgat ttttcagcca attgcctttg cttttcatta acaacaaata gaattgaacg
      601 atattgtttc ccccgatctt gaaattgacc aaaggcatct gtagggtctg aaatttgcca
      661 ataaatctcc aacagctctt cataggttat ttgacgtgta tcaaatatga tctcaacagc
      721 ttcaacatgc ccagtatatc caccactgac ttgatcgtaa tttggttttt tggtctctcc
      781 acctgtataa ccagataaca ctgagattac acctggtttt gtttcaaaag gctcaaccat
      841 acaccagaaa cagccaccgg caaaaatcgc ccgttcttgg tataagggtg aagttatctt
      901 atgtttggca taatcataag cctttgcact cgctgactcc cctgtgattc ttaaataaaa
      961 atccatcgca tctggtgtca aattatctcg tagtgctagc ggacgcaagt tgacctctag
     1021 tttttctatc acctgcttta tcgacatttt tgctaggtct tcttttgcct cttcaaattg
     1081 tgttctttcc cattctcttg tatttcgatt taaaataata ttataaaggt ctatttccat
     1141 ctgctccaca tctaacatga agtcaccctc tttcaagttt tcttcttatt cattcaaaaa
     1201 atgactacct gaaatttagc acaacgcata acaagttaag actaacttgc ttttcgctct
     1261 cctcatctct attcttagtc gaacacatcc acacgaatgg ttacccatag agaaattctt
     1321 ttacttaatc agcttcacac tgctttttct actttcgtag ttgaaaaaaa cttaaacaaa
     1381 tcatcggcaa atagttaaag aaaaaactta agcgttgaaa gaagcccaat tgcttaaaga
     1441 aggcaaactg actaatcgac ggaatccgtg ctaatctgta aagacctgca attagtaaac
     1501 taataactgt taaaacaaga taaaaatggc taagcgtacc ttgaccactt tgacgataaa
     1561 gcagaacaag taacaatggg aaaagtagaa agcctgcata gcctagccca gaacctatat
     1621 tatggatcca agtcgataga ttccaagagc tttcattcgt attgatactg aataacccag
     1681 taaaaataca atcacctatc ccatataaac caactgttgc aacagcaagt attgcaagtg
     1741 tttttgatgt tccaataaat aggtgataca acgcaggcaa cgaaagaaca aaaaaaagtc
     1801 cagatacaac tgaccagacc aagaaagcac gtctgactgg actatctacg tcaccaaaca
     1861 cactaattac ggtagtcatt tgattcagtt tgggataaaa aaggccaagg atatacggtg
     1921 tcgataaatc actaatcaca cctaataata aaaaataaaa accatatttt tgcaaaaaaa
     1981 tcattttctt ctcctacttt ttagtgatta ttcgatacat ccaacaatca aattttttct
     2041 cattttaaca catattttta ttctagttgc cttttgaaca atcaataaca taaaggtgag
     2101 tttcttctac attttaaaaa atcgaatggc actgaagagt tcagttgtca gcatcaatct
     2161 cctactcaaa aaggcaaaaa aacgtaagtc agatgttgtt gacatctcac ttacgcatcc
     2221 attgattgaa aatttcttag taaaatctac tagcctaaaa atttgaagac ttcttctcga
     2281 tcatacagtt taaatacttt ctcgcataaa aattgagtaa ttagtgccgc aaaaacaggg
     2341 atgactaacc aacaaagaac aacaagaaag ccatttagcc ctgcatctaa agaagccaac
     2401 ggaccaacaa gtccgaccac gccgaaacca gcagaagcag gcgtacctga aatagaaaat
     2461 agagcgacag gaatagctgt aatcactgca ctaactaaac aaggaataag aatcacaggt
     2521 tttctaaata gattaggcat catcatcttc atagcgccta aagcaatcgc aattgtcaca
     2581 cctgacttat taaccttcca agagttcact actaaaacaa aagtggttgc agctacgccc
     2641 atcgcagccg caccagcaga aacaccatct agttggattg ccattccgat tgctactgtt
     2701 gaaataggag agataatcaa aaaggcaaag gaacaaccaa tcaagataga cattaacagc
     2761 ggttgtaagg tagtgaagtt attaatcaat gatccaattg cagaagtaat tgctgttaca
     2821 aaagggaata aataaaaacc aagtaaacct gcacctacac ctacaacaat cggtgttaac
     2881 acaatcgaca ctgacccaaa actatttcca atcagtaaaa tcagcccgac agcaatcgat
     2941 gctgtcagca tcgtattaat aatatcgcct gtaccagcac caacgtaaac acccgtttca
     3001 cccaaatcag gtgtgaattt gactacacca gaaccaacaa aagaagctcc ggctacaacc
     3061 atcattctca tcggatcaaa tccaaattgt aaggcaatca aaccaccaat gatcaaaggt
     3121 gttgctagtt gaaaaataac tgctaactgt gcgatcgtta ccgcaaaggg atacgcacta
     3181 aaatatttta aaatggcacc taatactgca ttaggaatca atccaataat gattcctgtt
     3241 gctgtaccag cgaggacttt attcagaaaa attttcggtg atattttttg tgaagtttcc
     3301 attcaatctc tcctttattt tacgttcaaa ctatcttctt ttgcatggac aagctcagtc
     3361 aagaaatcac aataaggcgt cgcaacacca tatttcttcc cttttctaga aattgcgcca
     3421 ttgatataat cgatttctgt taatcgatgg ttcttaatca agtcttgata cattgaagga
     3481 taatgtaacc caattgtttc cgggtcaaaa caagattcac aatgtgcaat gacttctggg
     3541 acatctagtt caatcttctc tactgctgct actttggcaa actcattgac aatcgtcgcc
     3601 accattttat gagcagtcga tgtttttcct agctcagcca tattaacgtc taagattgtg
     3661 catagtccgt tcattgttcc gttcacacat gctttgcgat aaatagaata gtgaatattg
     3721 tcagaaaaat gagcatttaa tcctgattca gacaatttgt ctgctaattt ttttgcagct
     3781 gcttcttttc catcacctaa attttgtaat tctactgaac cacttccaaa taatttgacc
     3841 tgaccaggac cttcaagacc tgccgtccac atggtatttc caatatagat attttccatt
     3901 ggtacaaatt tctcaataat atcttcatgc ccgataccat ttaatagaca taagacctct
     3961 gtatcttttt tgattaatga ttggatatcc tgcagcattt tttccagctg catcgctttg
     4021 gtaaatagaa taatcagatc aacttgatct tctttttcta cttcggattg aagaacgatt
     4081 ggtagttttg cttctacctc tttaccatta aaatttgctt gtaatccatg ctctttgatt
     4141 tgttggacat gttctgccca gccatcgatt aataatactt cgttcccact ttggtgaagc
     4201 attaacccaa agcgacttcc cattgcgcca gcgcctgcaa ttgctatttt cattgattct
     4261 tcctcctttt tctttctatt atattcattt gagaatcatt tcacaacctt gttttgttat
     4321 tcttctctta tttatcatgt ttatatccac cattcaagtt attttatcag caaatcaata
     4381 aaaactggaa tagaatccca atttcatcgt aagagaaact agactagcaa taagaaaata
     4441 gaaacattca tagaaaaaac ctcactcctc tgattataaa agagggggca ttaacctcgt
     4501 gtatactaaa accttccatt cattcgatgg atgattttct ttttgtgaaa aaatattcat
     4561 tgtagtacga tgttgcgcaa cacagacgga tggtattgct tattatttat taaaatcgaa
     4621 caatacactt atttaaaaac ttctttccca gattttcttc catttttaca gttataacta
     4681 gtattatcat gaaaaatagc cttttattgt ctatgggaat aataatttaa aattggtact
     4741 tttttattaa ttagttcatc gcccaataat ctctccagtt tcttagcatc tcctgactca
     4801 accggaatta tccaagccca gtccaaataa ttttttaaaa tctcatcata ttttgcaaat
     4861 atttcattgc catattccgt ccttaaaatt atattttcag tgccagacaa gtgatttgta
     4921 ttgagttgat aaaaaagatc tccatctaaa aaaatatcat tagaagaaga tttccccaca
     4981 gtaatgacca ttccatcagc tctatgtgtt acatacaaat aattgtatga cctcatttca
     5041 cctaatgaat caattatttc ttgcccttta gctctaatat attgatctct attacctatc
     5101 tcactcttat ttaacaaaag ttttttcatg tcaaatttaa tcggctgttt tatttttgta
     5161 aattcgcttc tactactaat ccaatccgag attaattttt caacatgtcc cagagtaaac
     5221 tctgatttat tcgctaaata ctttttttgt tgtattaaag acatctttcc ccgaagctca
     5281 aaattgagcc tacatcgatt ctctatctct tcaaaaagca tcttatcttc atcattctta
     5341 tattcatcat tcataaaacc aatccagctc ctcgattaag ataatatttt aatctcatac
     5401 aaaaactagc tctcatcaaa acaaccattg ttttgatttc tcatgaaatt tctttatact
     5461 tttctccgat tataaattcc taaccccttg agaaaattac gcatatattt atctccgcaa
     5521 ggcttaaaat ttcgttggcc ttcttttctc aaaaatgccc cgatttcgcc ttttgatgga
     5581 tagatttctg cctcagcaaa aacgtctaaa atatcatcag tggtcataga caaggcgatt
     5641 tttaattttt ttagcaacac attgttgata tatttgattt ccttgctttt ttgcggcgtg
     5701 tctactatcg gcttatcttt ttgcggacca cgcgccaaga gaatcaggcc atttaggaat
     5761 gcgtcaaaaa cttggttgtt gatggttttt tcatacacat tattttctgc attatctttg
     5821 ttcttatcct gtactttggt cagtaccgcc tgagcttctt ctttagtcag tggtacaccg
     5881 cctagctcaa aagctttaat caaatccgta tctttcaaat caatcgcata acgcaatcgc
     5941 aataacctat cattgttatt catttgttcc tccgaagtat ttagtcttta ctttcttacg
     6001 tactttttgt cttgctaaga tttttaggat caatgataaa aaccgcatca cttatgataa
     6061 ggcgcccccg cattgatccg gaaggcacgg tagatttgct cgacaaggat cagacgcatc
     6121 aattgatgtg gatacgtcat ttttccaaaa gagatctgag cattgcttct tttcatgacg
     6181 gcttcgctga gtcctaaaga gccgccgata acaaaaacaa ggtggctttt tccttggata
     6241 cctaattggt cgatttgttt agcaaaagat tcacttgtag gatttttccc ttcaattgct
     6301 aaggcataga cgtattcttg ttctttgatt ttcgctaaga tccgttcccc ttctttttct
     6361 tttacttgtc tcatttgcgc ttcgcttaaa ttctccgggg ctttttcgtc aggaacttcg
     6421 atcaattcga tttttgcata ggcattcagc cgtttgacat actcattgat accttggatc
     6481 aggtattttt cttttaattt tcctactgag ataattttga tattcatgtt ttctctcctt
     6541 tggtcttcat gctcactttg tttattataa tcaatttttt cgtctatatg tttattttgg
     6601 ctatttttgt taaaaagatt tccccaacag ttatgcacaa catccacagg tttatccaca
     6661 gaaaacagtg ttattttacc ttatttcatc acattcatta ggcaaacata cgttttataa
     6721 gaatttatcc actttataca caggctgtgg atatgtttta tcccttattt ttccaatcct
     6781 atccgcgtag ttttacacag tatctgtgga aaaagaaaat caaatatttt catctgaaaa
     6841 caatgatttt tcctaaagtt tttcataaaa agttcacagt ctcaaagtag actaaagtca
     6901 acaaataaga ctatactaac agtagataaa tgaatgtaat tggaggagga acacatggat
     6961 agaaaaaatg tgacaccaaa gatgaaaaaa agtaaaaata atagcctctg gcgtaagtta
     7021 ggtctggggc ttgttggagg gatcgttgga ggactactga cagctggcat tttttatgca
     7081 gcgatgggca ctggcaacaa tagttctact gctacaagcg gcaatcagaa ttctgccggt
     7141 gaaacagttg tggaaaatat caaagtcaat gtagattctg atatcaccaa agcggtagat
     7201 aaagttcaag acgctgtcgt ttctgttatc aacttacaaa gtcaaaacca atcaagcggt
     7261 tttggcggac tattcgggca gcaagaagaa agtagcagct cagatgatag taatttggaa
     7321 gcttatagtg aaggaagcgg cgtgatctac aaaaaagacg ggaatactgc ttatgtagtc
     7381 acgaataatc acgtagtaga tggccagcaa ggtcttgaag tcttgatgaa agacggtacg
     7441 aaggtaaaag ctgaattagt tggaacagat gcttattcag atttagcggt gttgaagatc
     7501 aattcagaca aagtcgaaac agttgcctct tttggtgact caagtgctct gaaggttggt
     7561 gagcctgcga ttgcgattgg ttccccacta ggatctgaat atgcaaattc tgtcacttca
     7621 ggaatcattt cttccttgaa ccgacaagtg acaagtacga atgaatcgaa cgaaacagtc
     7681 aatatcaatg cgatccaaac agatgcagca atcaaccctg gaaattctgg tggtccttta
     7741 gttaatatcg aaggacaagt tatcggtatc aactcaagta agatcgcaag tacttctgaa
     7801 tctacttcta atgtaagcgt agaaggaatg ggatttgcta ttccaagtaa cgatgtagtg
     7861 aatatcatca atcaactgga aaaagacgga aaagtgacac gtccagctct aggtatcaca
     7921 atggtcgact tatctgccgt ttctactcag caacaagaac aaatcttgaa gattccttca
     7981 tctgtaacta acggtgtcat cgtgacaaat gtccaaacag ctacaccggc tgaaaaagct
     8041 ggattgaaac aatacgacgt cattactaag atcgatgaca aagaagtttc ttctggtgta
     8101 gaacttcaat ctgctttgta taagaaaaaa gtgggagatt ctgtcaaaat cacttactat
     8161 gaaggctcga aagaaaaaac aactactgtt gaattgacga tcgatcaatc ggcattaaaa
     8221 caaaatcaaa atagtgaaaa ttaa
//
LOCUS       DAFBVQ010000089         7760 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.093, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000089 DAFBVQ010000000
VERSION     DAFBVQ010000089.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7760)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7760)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7760
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.093"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(552..1898)
                     /gene="gor"
                     /locus_tag="LLC22_002560"
     CDS             complement(552..1898)
                     /gene="gor"
                     /locus_tag="LLC22_002560"
                     /EC_number="1.8.1.7"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376012.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione-disulfide reductase"
                     /protein_id="HBK5435780.1"
                     /translation="MQIYDYIVIGGGSGGIASANRAGMHGAKVLLIEANELGGTCVNV
                     GCVPKKVMWQASTILETIERDASSYGIQADLKNVDFAGLVERREKYIDFLHGAYQRGL
                     DSNHVEAIKGYATFIDSQTIEVNGETYRAPKILIATGGRASKMTIPGGEYAIDSNGFF
                     ELTELPKRAIVLGAGYIAAELSGVFRGLGSEVMWAYRKERPLRTFDKMLSDNLIQMYQ
                     EAGIKTYAHHIAKEITKNNDEYTVLFENGETLTGDCVLFAGGRVPNTEKLGLENTNVE
                     LDKKGFIKVDKYQNTTDEHIFAVGDVIGKLDLTPVAIAAGRRLSERLFNGKKDSYLDY
                     KLVPTVVFTHPPIATIGLTEEEALEKYGENELKVYRSRFTPMYFALNDYRQKCEMKLI
                     CVGKEERIVGLHAIGVGVDEMLQGFAVAIKMGATKEDFDNTVAIHPTGAEEFVTMR"
     gene            complement(2032..3285)
                     /locus_tag="LLC22_002561"
     CDS             complement(2032..3285)
                     /locus_tag="LLC22_002561"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBK5435781.1"
                     /translation="MMKEMTVKRKLKRPEILAPAGTLEKLKTAIHYGADAVYIGGNAY
                     GLRSRAGNFTYEEMAEGVAFAKEHDAKVYVAANMVTHEGNEDGAGEFFRSLRDVGISA
                     VIVSDPALIEICATEAPGLPIHLSTQASATNFETLEFWKEEGLERVVLAREVSMEEVA
                     EIRKNTDTEIEAFIHGAMCISYSGRCTLSNHMSMRDANRGGCSQSCRWKYGLFDMPFG
                     QERNSLTDTGEVEEEFSMSAVDMSMIEHIPELIENGVDSFKIEGRMKSIHYVSTVSNV
                     YKAAVDSYMEDPENYVCKQEWIDELWKVAQRELATGFYYNTPTENEQLFGERRKIPVY
                     KFVGEVLSYDEATQIATIRQRNLFSVGDEIEFYGPGFSHFSQTVEVMHNEEGESIDRA
                     PNPMMILTMPVAQPVKPGDMIRKRK"
     gene            complement(3291..4214)
                     /locus_tag="LLC22_002562"
     CDS             complement(3291..4214)
                     /locus_tag="LLC22_002562"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="U32 family peptidase"
                     /protein_id="HBK5435782.1"
                     /translation="MIELITTVETIEQAEQLLAAGADTLYFGEEQFGLRLPASFTREE
                     QRQLVELAHKYGKKANIAVNGIIHPEKMKNVPEYLAFLKEINVDVITVGDTGIIYTMK
                     KNPELRIPYIYDAETLVTSARQINFWAKKGAVGAVLAREVPFEEMKAMEEKLDIPVET
                     LVYGATCIHQSKRPLLQNYYNYTKQDEQKDRERGLFISEPKKEETHYSIYEDSHGTHI
                     FASNDLNLSNELNELYQHHYCTWKLDGLFTPGEKFVNITRLFAEAKKQILEGSWDQEK
                     AEKMTSEISKLHPENRELDTGFFYIDPSAIK"
     gene            complement(4435..6927)
                     /locus_tag="LLC22_002563"
     CDS             complement(4435..6927)
                     /locus_tag="LLC22_002563"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent Clp protease ATP-binding subunit"
                     /protein_id="HBK5435783.1"
                     /translation="MEELFTERAQAVLEIAQEEAKRLKHQSVSSEHVLLALVVEQNGI
                     AGKVLREMDLNETEIYEEIEHLIGYGGIRSYPKGVFLPYSPRMKQVFALASSEVKKTG
                     SQKVGTEHILMSLLKDESIMATRIMINLGISLSKARQVLKQKMGLAGDSAGKGMNRRR
                     NVNVQDKRQTPQGTPTLDSLARDLTKLAKENKLDPVVGRSREVKRLIQILSRRTKNNP
                     VLVGEPGVGKTAIAEGLAQKIILGEVPEDMQEKRLMMLDMGSLVAGTKYRGEFEDRMK
                     KVIDEIYNDGQVILFIDELHTLIGAGGAEGAIDASNILKPALARGELQTIGATTLDEY
                     QKYIEKDSALERRFARIQVDEPTPEEAEVILQGLRTRYEEHHGVEITDEAVRAAVNLS
                     VRYITSRQLPDKAIDLIDESAAKVRLDQTDHLTKSTVIKLEIDELVQEKEAAIQKQDF
                     ENAAQLRRQEKALRKKLQKVSAIEAKQEQGYSDRVTEEDVATVVSEWTGVPLQQLEKK
                     ESERLLELEGLLHERVVGQDEAVKAVSRAIRRARSGLKDPDRPIGSFMFLGPTGVGKT
                     ELAKALSEVMFGSEDALIRVDMSEFMEKYSTSRLIGSPPGYVGYDEGGQLTEKIRQKP
                     YSVILLDEVEKAHPDVFNLLLQVLDDGHLTDSKGRKVDFRNTIMIMTSNIGATQIREE
                     KNVGFNVQDVTKDHKAMQKRILEELKKAFRPEFLNRIDETVVFHSLSKDEIHTIVQIM
                     SKAIIKRLKEQDIQVKITPSAIDVIGKAGFDPEYGARPIRRALQKEIEDRLSEALLGG
                     EIRLGDHVTVGASKGKITLNVRGPKKETVGSL"
     gene            complement(6934..7401)
                     /locus_tag="LLC22_002564"
     CDS             complement(6934..7401)
                     /locus_tag="LLC22_002564"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CtsR family transcriptional regulator"
                     /protein_id="HBK5435784.1"
                     /translation="MAHQNTSDLIESYIKKILENSEMIEIRRIEMADLFNCVPSQINY
                     VINTRFTIQRGYLVESKRGGGGYIRIAKVRISDKKQLLEQINQLFDDTISEKNAFAII
                     QKLYEDQIITKKEGNLMLSAIAKNTLNFNEYEDHTRARILRAFLERLSYEDGK"
     gene            complement(7537..7610)
                     /locus_tag="LLC22_002565"
     tRNA            complement(7537..7610)
                     /locus_tag="LLC22_002565"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7574..7576),aa:Arg,seq:acg)
     gene            complement(7668..7741)
                     /locus_tag="LLC22_002566"
     tRNA            complement(7668..7741)
                     /locus_tag="LLC22_002566"
                     /product="tRNA-Pro"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(7705..7707),aa:Pro,seq:tgg)
BASE COUNT         2161 a         1691 c         1247 g         2661 t
ORIGIN      
        1 aaatcagtgt tttgtcctga gtattagaga aacaaatgga aaaatagttc ctcatatttt
       61 gccgtttttt gagctaatac cgaaggacag ctgattgaac actatttgtt cggaaaaagt
      121 gactaactat gacacaattt ttttcacagt cccttttttc acttgatttg attcgtacca
      181 gcgaacttga cgagaacttt cttggtttgg taactatatg gtattctttt aacatcctcg
      241 tttgcttctt ctaatttatt tatacaaagt cacacttttt taaacatctg ttcttcgata
      301 catttctatt tcttttaaac atcgatacca atattttgaa cttaagagtg cataccaaat
      361 ggattcattt actcttcgtc agttacgaag ataatcaaaa tctccaactt ccctacttat
      421 ttcgttttga gaattatcga agcaatctta cataaataac taaaaaacaa aaaaccagaa
      481 aatcagtata ctgattttct ggttttacat ggtttgttca ataaaaagct gttggaactg
      541 ttaatattaa attatcgcat cgttacgaat tcttccgctc ctgttggatg gatggctact
      601 gtattgtcaa agtcttcttt agttgcaccc atcttgatag ccacggcaaa accttgcagc
      661 atctcatcga caccaacacc aatagcatgt aagccgacga ttctttcttc ttttccgaca
      721 cagatcaatt tcatttcgca tttttggcga taatcattta atgcaaagta cattggggta
      781 aagcgtgaac gataaacttt caattcattt tcgccatatt tttccaatgc ttcttcttct
      841 gtcaaaccaa ttgttgcaat tggtggatgc gtaaagacga ctgtcggaac aagtttatag
      901 tcaagataag aatctttctt tccattaaat aaacgttctg ataaacgtct accagctgcg
      961 attgcaacag gagtcagatc taatttaccg atcacatcac caacagcaaa aatatgttca
     1021 tccgttgtat tttggtattt atctactttg ataaaccctt ttttgtccaa ttccacattt
     1081 gtattttcca gacctaattt ttcggtattc ggtacacgtc caccggcaaa aagtacacaa
     1141 tcaccagtta aggtttcacc attttcaaat agcaccgtat attcgtcatt gtttttagta
     1201 atttctttag caatatgatg tgcgtaagtt tttattccag cttcttggta catttggatc
     1261 aaattgtccg aaagcatttt atcaaacgtt ctaagtggtc gttcttttcg atatgcccac
     1321 atgacttcac tacctaaacc acgaaataca cctgaaagtt cagccgcaat gtatccagca
     1381 cctaaaacga ttgctctctt aggtaactct gttaattcaa aaaatccatt tgaatcaatt
     1441 gcgtattctc caccaggaat ggtcatttta cttgcacggc ctccagtagc gatcaagatt
     1501 ttaggagcac gataggtttc accgtttact tcgatcgttt gactatcgat aaaagtagcg
     1561 taacctttta tagcctcgac atgattgcta tctaatcctc tttgataagc accgtgtaga
     1621 aaatcaatat atttttctcg tctttctact agaccggcga aatcaacatt ttttaaatct
     1681 gcttggatac cgtaacttga ggcatctcgt tcaattgttt ccaaaatcgt acttgcttgc
     1741 cacataactt ttttaggtac acaaccgacg ttgacacatg ttccgcccaa ttcattcgct
     1801 tcaatcagca aaacttttgc gccatgcatc cctgctctgt ttgctgaagc aataccgcca
     1861 gagccgccac caattacgat gtaatcatat atttgcattt tgttcctcct tattgaagag
     1921 atcaatcaaa acctttattt aacgatcctt tttctacaga aaacaagtgt aacacttttc
     1981 ttgaattttg tatgcgaaga tgcttaaaac agggatatat cagctttttc cttatttacg
     2041 ttttcggatc atatctccag gtttcaccgg ctgtgcgact ggcatagtta aaatcatcat
     2101 tggatttggt gctcggtcaa tggattcgcc ttcttcatta tgcataactt caacggtttg
     2161 actgaaatga ctgaatcctg gaccataaaa ttcgatttca tctcctacag aaaacaagtt
     2221 tctctgacgt atcgtagcaa tctgtgttgc ctcatcataa gataatactt caccgacaaa
     2281 tttatatact gggattttac gacgttcacc gaataattgt tcgttttcag ttggtgtatt
     2341 gtagtaaaaa cctgtagcta attctcgttg tgctactttc cataactcgt cgatccattc
     2401 ttgcttgcag acatagtttt caggatcttc catataactg tctacagccg ctttatagac
     2461 atttgacacc gtagatacat aatggatcga tttcattctt ccttcgatct tgaagctgtc
     2521 tacgccgttt tcaatcaatt ctggaatatg ttcgatcatt gacatatcca ctgcactcat
     2581 cgagaattct tcttccactt cgcctgtatc agttaaactg tttcgttctt gaccaaaagg
     2641 catatcgaac aatccatact tccagcgaca agattgagaa catccgccac ggtttgcatc
     2701 ccgcatcgac atatggttgg acaatgtgca tcgaccagaa taagagatac acatggcacc
     2761 atggataaat gcttcgattt cggtatccgt atttttacga atctctgcca cttcctccat
     2821 tgaaacttca cgagctaaaa cgacacgttc caacccttct tctttccaga attccaatgt
     2881 ctcaaaatta gttgctgaag cttgagtgga taaatggatc ggcagacctg gggcttctgt
     2941 cgcacaaatt tcgatcaaag ctggatcaga aacaatcact gcagaaatac cgacatcacg
     3001 caaactgcgg aaaaattccc ctgctccatc ttcatttcct tcatgggtga ccatattagc
     3061 agcaacgtat accttcgcat catgttcttt tgcaaaagca actccttcag ccatttcttc
     3121 ataagtaaaa ttacctgcac ggcttcttaa accatatgca ttcccgccaa tatatactgc
     3181 atctgctcca taatggatcg cggtttttaa cttttccagt gttcctgctg gcgctaggat
     3241 ttctggtcgt ttcaattttc tttttactgt catttctttc atcatactcc ttatttgata
     3301 gcagaaggat caatataaaa gaatcctgta tctaattcac ggttttcagg atgcaattta
     3361 ctgatttcgc tagtcatttt ttccgctttt tcttgatccc agctaccttc taaaatttgt
     3421 ttttttgctt cggcgaatag tcgagtgatg tttacgaatt tttcgcctgg agtaaataat
     3481 ccgtccaatt tccatgtaca gtaatgatgc tgataaagtt cattcaattc attcgagaga
     3541 ttcagatcat tgctggcaaa aatatgtgtg ccatgactat cttcataaat agaataatgt
     3601 gtctcttctt ttttaggttc cgagataaaa agacctcttt cacgatcttt ttgttcgtct
     3661 tgtttcgtat agttatagta attctgtagc agtggacgtt tggattgatg gatgcatgta
     3721 gcaccataca caagggtttc tacaggaata tcgagttttt cttccatcgc cttcatctct
     3781 tcaaaaggaa cttcacgagc aagtactgct ccaactgcgc cttttttcgc ccagaaattg
     3841 atttgacgtg cgctcgttac taatgtttca gcatcataaa tatacggtat acgcaattca
     3901 ggattttttt tcatcgtata aataatacct gtatcaccaa ctgtgatcac atctacgttt
     3961 atttctttta aaaaagccaa atattcaggt acatttttca ttttttcagg atgaatgatc
     4021 ccatttacag caatattcgc ttttttacca tacttgtgtg ctaattctac caattgtcgc
     4081 tgttcttctc gtgtaaatga agcaggcaga cgcaatccaa attgctcttc accgaaatat
     4141 agtgtatctg cacctgcagc aagcaactgt tctgcttgtt caatagtttc tactgtggtt
     4201 atgagttcga tcataatttt ctcctcctac aacttcataa tagtagcata gctctaaaaa
     4261 ctttccaata cttcttctat ttaaagtcgg atttttgaaa attatttcac aaaaaatcaa
     4321 aataaagttc gatatattct gtccaaatat aaaaagagat tgtgacaaaa atcttgtcac
     4381 aacctcttaa tcaagtctta ctattataaa aattcagcta cacaggccaa gtaactatag
     4441 ggaacctact gtttcctttt taggtccgcg aacattcaat gtgatcttac cttttgaagc
     4501 acctactgtt acgtggtcac ctaaacgaat ttctccgcca agcaaagcct cgctcaatcg
     4561 atcttcaatt tctttttgaa gtgcgcgacg gattggacgt gcaccatatt caggatcaaa
     4621 tccagctttc ccgatcacat cgattgcaga tggtgtgatt ttcacttgaa tatcttgttc
     4681 tttcaatcgt ttgataatcg ctttgctcat gatttggacg attgtatgga tttcatcttt
     4741 actcaatgaa tggaagacga cagtctcatc gattcgattc aagaattcag gtcggaaagc
     4801 tttctttaac tcttctaaga tacgtttttg catggctttg tgatctttag taacatcttg
     4861 gacattgaat ccgacatttt tttcttctcg aatttgtgtc gctccgatat ttgaagtcat
     4921 aatcatgatt gtatttctaa agtccacttt tctaccttta gaatctgtta aatgaccatc
     4981 atccaatact tgcagaagta aattgaaaac gtctggatgt gctttctcca cttcatctaa
     5041 gagaatcact gaatatggtt tttgacgaat tttttctgtc aactgtccac cttcatcata
     5101 ccctacgtat cctggaggag acccgattaa tcggcttgta ctgtattttt ccataaattc
     5161 tgacatatca acacggatca gggcatcttc acttccaaac atgacttctg aaagtgcttt
     5221 ggccaattct gtttttccga caccagttgg tccaaggaac atgaatgaac caattggacg
     5281 atcaggatct ttcaatccgc ttcgtgcacg gcggatcgca cgtgaaactg ctttgacagc
     5341 ctcatcttga ccaacgacac gttcatgcag aagtccttcc agttctaaca agcgttcgct
     5401 ttcttttttc tccaactgct gtagagggac accagtccac tccgatacaa ctgtagcaac
     5461 atcttcttct gttacacgat cagaataacc ttgctcctgt tttgcttcaa ttgcagaaac
     5521 tttttgcagc tttttacgta gtgctttttc ttgtctgcgt aattgagcag cattttcaaa
     5581 gtcttgtttt tggatcgctg cttccttttc ttgtactagt tcatcgattt ctagtttgat
     5641 cacagttgat tttgttaagt gatcggtttg atccaaacgg actttcgctg ctgattcatc
     5701 gatcaaatca attgctttat cgggtagttg acgagaagtg atataacgaa cagaaagatt
     5761 gactgctgct cgtacagctt catctgtgat ctccactcca tggtgctctt catatcttgt
     5821 acgtaatcct tgaagaatca cttctgcttc ttcaggagtt ggctcatcta cttgaatgcg
     5881 agcaaaacgt cgctctaatg cagaatcttt ttcgatatat ttttgatatt catctagggt
     5941 cgttgctccg atcgtttgta attctcctcg agctaacgcc ggtttcaaga tattcgaagc
     6001 atcaattgct ccttctgctc cacctgcacc aattaaggta tgcaattcat caatgaataa
     6061 gattacttga ccatcattat agatttcgtc gatgaccttt ttcattcgat cttcaaattc
     6121 accgcgatat ttcgtaccag caaccaaaga tcccatatca agcatcatca ggcgcttttc
     6181 ttgcatgtct tctggcactt cacctaaaat gattttttga gctaaccctt cagcaatggc
     6241 tgttttgcct acaccaggtt cacccaccag tacagggtta ttctttgtcc gtcggctaag
     6301 aatctggata agccgtttca cttctctcga acgaccaaca actgggtcca gcttgttttc
     6361 ttttgctaat ttcgtcaaat cacgtgctaa tgaatctagc gtaggtgttc cttgcggtgt
     6421 ttgccgttta tcttgtacat ttacatttct acgacgattc attccttttc cagcagaatc
     6481 accagctagc cccatttttt gtttcagaac ttgacgggct tttgaaaggc tgatacctaa
     6541 gttgatcatg attcgagtag ccatgatact ttcatctttt aataagctca tcaaaatatg
     6601 ttctgttcca actttttgag aaccagtttt cttcacttcg ctgctagcta aagcaaaaac
     6661 ttgtttcatt cttggtgaat atggaagaaa gactccttta gggtaagaac ggataccacc
     6721 ataaccaatc agatgttcaa tttcttcata aatttccgtt tcattcaaat ccatttcacg
     6781 taatactttt ccagcaattc cattttgctc gaccactaag gctagtaaaa catgttctga
     6841 actaactgat tgatgtttca accgttttgc ttcttcttgt gcaatttcta atactgcttg
     6901 ggctctttca gtaaaaagtt cttccatcta atctcacttc ccatcttcat aacttaaacg
     6961 ttccagaaat gctcggagaa tccgagcacg tgtatgatct tcatattcat tgaaattcaa
     7021 tgtgtttttt gcaattgcac tcaacatcaa gtttccttct ttttttgtaa ttatttggtc
     7081 ttcataaagt ttttgaataa tagcaaaagc atttttctca ctgattgtat catcaaataa
     7141 ctgatttatc tgctcaagta attgtttttt atctgaaatc cttacttttg caattcgtat
     7201 ataaccacca ccaccacgtt tgctttctac tagataacca cgttggatgg taaaacgggt
     7261 attaatcaca tagttgattt gtgaaggaac acagttaaag aggtctgcca tttcaatcct
     7321 tcgaatctcg atcatttcac tattttccag aattttcttt atatatgatt caattaaatc
     7381 cgaggtattc tgatgtgcca tcttattcat tccctttgac taatattgac cttaattata
     7441 acgaatttga taatagaaag aaagaagaac gctttttgtt aaataaatcc tttagaatca
     7501 acaaaaaaaa atacggaata tactattccg tatcgacgcg cccaagagga gtcgaacccc
     7561 taaccttttg atccgtagtc aaacactcta tccagttgag ctatgggcgc atattcaatt
     7621 taaaaaaatt ataaatcatt tgaaaacaaa aagcaagata aaaaaaatcg ggaagacagg
     7681 attcgaacct gcgacccctt ggtcccaaac caagtgctct accaagctga gctacttccc
     7741 gtttaaaaaa taaaaaagac
//
LOCUS       DAFBVQ010000090         7625 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.094, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000090 DAFBVQ010000000
VERSION     DAFBVQ010000090.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7625)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7625)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7625
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.094"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(14..706)
                     /locus_tag="LLC22_002567"
     CDS             complement(14..706)
                     /locus_tag="LLC22_002567"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874227.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5435785.1"
                     /translation="MQIELQHTHDKETFEKNYKVYVELARDSAMKYGIPLTLDTPYNQ
                     PGIKSHLWVTQNIWGDHTDPYGYLSEIGVSKEKLAYDLAHGFTDDNPTTSEDKPVIDP
                     TRAGAANSTLTDGTNYAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKELAR
                     VRADGIYRPDVNQAYNTLGNVGYHVSFNMRDFPNKKVYVMMRATNDPEGNTKGGAQDF
                     HDKRWYLNIPQR"
     gene            complement(1143..1712)
                     /locus_tag="LLC22_002568"
     CDS             complement(1143..1712)
                     /locus_tag="LLC22_002568"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5435786.1"
                     /translation="MELKKLEVPTSSITEVKRSPMDVFAQARDAGTGVYIFNREKVAG
                     VMLTQEQYETLLQELDVLRQTVKVERKEPKEINEEPINKTASVVSNAEGMEELAQTLQ
                     HSLITGVTITAKNLDERMVALGFITKKTGFGGVVDMLSELMETGKINYQLRRKPQNRT
                     IIAEIIGEQNSQSQLMDKIIIKKIFLHEL"
     gene            complement(1786..2109)
                     /locus_tag="LLC22_002569"
     CDS             complement(1786..2109)
                     /locus_tag="LLC22_002569"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435787.1"
                     /translation="MLLLKTLQERGYLDVHPPEVKIVFFFRYEHQEARRLAGVLNKTL
                     RHRKRISIHVCTRNKPPRYADLVIIDHFFPLDHNEDQKTYLYHPSFGIERLLTDINYW
                     LGKNR"
     gene            complement(2263..3075)
                     /locus_tag="LLC22_002570"
     CDS             complement(2263..3075)
                     /locus_tag="LLC22_002570"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435788.1"
                     /translation="MRWQKLLSKNAQNLFSLINLMKDLIWRKADLAEELKIDVKTVDR
                     HLKRLAESDCPIQLILHKKTVQLVYDQGYSEPYLLFVFLIQSPPFCLLKNLLLNEPYE
                     QKYDRSTQERLRKWFGEYHLSFSYKKAQIFGSERKVRYLLFCFLKDFPHFFADDGEQS
                     FSEMFIQLLKQRKDPAEIEILGDSRTLFFELFPELLFREEQILPIKEKNYLAILRLSC
                     NQITEKRWKRIEETQDYRKLTIVTEKLDSLFWLNSEFESESKSKLTKVLYQE"
     gene            3429..4277
                     /locus_tag="LLC22_002571"
     CDS             3429..4277
                     /locus_tag="LLC22_002571"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008274428.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MoxR family ATPase"
                     /protein_id="HBK5435789.1"
                     /translation="MIVALLAGGHVLFEDIPGVGKTLLVKALAKAVQGTFSRVQCTPD
                     LLPSDILGFSVYNSQSKEFEFRPGPIFTTILLADEINRTTPRTQSALLEAMAENHATI
                     DNNTYPLDNHFFVLATQNPIEYEGTYPLPEAQLDRFLFRLQIGYPSFDDELLLLLDKF
                     EKVLDNLNEVLNSYEIEEIKTNVANVFVSPEVASYALQLVSATRSHAAIQLGISPRGS
                     LSFIQAAKAYALIHGRNYVTPKDLQDLVPYVFSHRLIFYDRSLKEDEKKQIIHTLVAQ
                     IPIPVR"
     gene            4422..5363
                     /locus_tag="LLC22_002572"
     CDS             4422..5363
                     /locus_tag="LLC22_002572"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304699.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF58 domain-containing protein"
                     /protein_id="HBK5435790.1"
                     /translation="MELDFIKQLSKETFGYLYIAATRLSQKKYAGYFFHSKKENFFFT
                     SPSFTNRLPSNLCRKKQEILILTNKPQEVQLLWQPKERGCHETLTVIFTAYDSLGLFR
                     KSAKREISFPVTVLPAFCKIQAEKLQRVLEKKQQLNAYQRGLDFREHRAYRPGDSFNR
                     IDWKLSAHTQEWLYREYDYQEEECSPLFCFWGSPSPKFEPLLDLYFSLWHLRKEKQPE
                     LLILGNRAFHGKDPGHTYFASLEAGDEKTFFAHLKKYAKKQIVLFVPENSPEVSEAIE
                     TLSKDRTVYLVYFVEKQLMVQEKDKICSLPGGEWIDD"
     gene            5353..7524
                     /locus_tag="LLC22_002573"
                     /pseudo
     CDS             5353..7524
                     /locus_tag="LLC22_002573"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343611.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transglutaminase domain-containing protein"
BASE COUNT         2272 a         1512 c         1371 g         2470 t
ORIGIN      
        1 agggggggat tttttatcgt tgtggaatat ttaaatacca acgcttgtca tgaaaatctt
       61 gtgctccacc cttagtattt ccttctggat cgtttgtcgc acgcatcatg acgtatactt
      121 tcttattagg gaaatcacgc atattgaaag atacatgata gccaacattt cctaaagtat
      181 tataagcttg atttacgtct ggtctataaa tcccatcagc tcttactcta gctagttctt
      241 ttccagtatt gtagtccata atgaaaatat actcgtattt ataattagca atgtgccatc
      301 cagctacatg caagtttgcg ttttcgattt ctccgaactg atcaatgtgg gcgtaatttg
      361 ttccatctgt cagcgtagaa tttgcagcac ctgctcgagt tggatcaatt actggtttat
      421 cctccgaagt agttggatta tcatccgtaa aaccatgagc caaatcatag gctagttttt
      481 ctttacttac acctatttca gaaagataac cgtaaggatc tgtatgatcg ccccaaatat
      541 tttgtgttac ccataaatgc gatttgattc ctggttggtt ataaggagtg tctaatgtta
      601 atggaatacc atatttcatt gctgaatctc ttgccaattc aacgtatact ttatagttct
      661 tttcaaaagt ttctttatca tgtgtgtgtt gtaactcgat ttgcacagga cttttggctc
      721 acgaggttgt cctactctac atcttgctga tagatatgct gaaaggaaaa caccaacatt
      781 atgttttgct ttttcagcta gaacgagaca agcaggaata cctttagaag atatcaaagg
      841 ttttttaggt cataaagatg tttccactac acaagtctat gcccatattt ctcccgaagt
      901 gaaaaaaaga tcaatgaatc aactagaaaa ctatatagaa gagcaaataa aaaagcactc
      961 aaattgagtg cttttttaag ctcactatca ctaaaactat cactaatttt atttataagc
     1021 gaacatgttt ctatcactga ttttttaaat ctagcgaaaa acccttatct taaaggcgtt
     1081 cgttcaattc tttggcaagg tcttcaaagc ctggcttgcc tagaagtgcg aacatggttt
     1141 tcttatagct catgtagaaa aattttcttg atgatgattt tatccatcaa ttgagattga
     1201 ctgttttgct ctcctatgat ttcagctatg attgtccgat tttgcggttt tcttcttaac
     1261 tggtagttga ttttcccagt ttccatcaac tcgctaagca tatccacgac tccgccaaat
     1321 ccggtctttt tcgtaataaa acctagtgct accattcgtt catctagatt ttttgctgta
     1381 atcgtcacac cagtaatgag cgagtgctgt aatgtttggg ccagctcttc catcccttca
     1441 gcattggata cgacggaagc tgttttgtta ataggttctt cgtttatttc ttttggttct
     1501 ttcctctcca ctttcactgt ttgacgaagg acatctagtt cttgcaagag cgtttcgtat
     1561 tgttcttggg tcagcatcac gccagctact ttttcacgat taaatatata tacgccagtt
     1621 cccgcgtctc gcgcttgagc aaatacatcc atcggcgatc gtttcacttc tgtgatcgaa
     1681 gatgtgggaa cttctaattt ctttaattcc aatggatttc ctcctttact aatcgctttt
     1741 tattatagca cagactgact tgttttgatc ttttttccaa aggttttatc ggtttttgcc
     1801 taaccagtaa ttgatatcgg taagaagtct ttcgatacca aatgaaggat ggtacagata
     1861 cgttttttga tcttcgttat ggtctagtgg aaaaaaatga tcgatgatca ctagatctgc
     1921 ataccgaggc ggcttatttc gagtacatac atgtatagag atccgttttc gatgtcttag
     1981 cgttttgttc agtaccccag caagtcttct tgcttcttgg tgttcatagc gaaaaaaaaa
     2041 gacgattttc acttcaggag ggtggacatc taaataccct cgttcctgga gtgttttcag
     2101 taaaagcatc ccccactcta ctgcggggtg tgcaagtgct tgttggatcg ctagccgaaa
     2161 ttgatatagt ttatctttgg aattgggaaa tttttctaat gtttcctgat aataacgaac
     2221 ttcttctatc agccggtcat ggataccaat tacgtaacga agtcattctt ggtaaagtac
     2281 ttttgtcagc tttgatttgc tttcgctctc aaattcgcta ttcagccaaa acagcgaatc
     2341 aagcttttca gtcacaatcg tcaatttccg atagtcttgt gtctcttcta tccgtttcca
     2401 ccgcttttca gtaatctggt tacagctcaa gcgcaaaatt gctagataat ttttttcttt
     2461 tattggcaaa atctgctcct ctctaaatag caattcagga aacaattcaa agaatagtgt
     2521 tcgactgtct cctaaaatct cgatttctgc cggatccttt ctttgcttca ataattggat
     2581 gaacatctca gaaaaggact gctctccatc atctgcaaaa aaatgcggaa aatctttcaa
     2641 aaagcaaaac agcagatatc ttacttttct ttctgaacca aagatctgtg cttttttata
     2701 agaaaaagaa aggtggtact cgccaaacca ctttctcaat cgctcttgcg tagaacgatc
     2761 gtacttctgc tcgtaaggtt cattcaatag cagatttttc agtaaacaaa acgggggtga
     2821 ttggatcaga aaaacaaaca agagataagg ttcgctatat ccttgatcat aaactaactg
     2881 aacggttttc ttatgaagaa tcagctgaat gggacagtcg ctttccgcca aacgtttcag
     2941 atgccgatcc actgttttaa catcgatttt cagttcttca gctaaatcag cttttcgcca
     3001 gatcaaatct ttcattagat tgattagtga aaataaattc tgtgcatttt ttgataatag
     3061 tttttgccat ctcatcgatc atttctcacc tgatttctaa acatattgtt tgatcaaaat
     3121 gggttcactc ctaaaaagat aaaaaactcc ctttctattt atttaaatac gcaaatcttc
     3181 ctcattattt tttattttac tcaatttaat cgtattctca tttcaaaacg aatgtacttt
     3241 aaaaaaacat aataagatca ctttgcttgt aggatgtatt cccttccatt acaatgaaat
     3301 aaatagcgat tttatgagaa ggtgatgtga aaatggaaga aaaaatagaa gaatccaaac
     3361 aaaaaatcga tcagttgata taagaattag aaaaagcggt catcggcaaa cgttcaacta
     3421 tccaattgat gatcgtggcc ctattagcag gtggtcatgt cttattcgaa gatattcccg
     3481 gtgtaggtaa aacgttactg gtcaaagcac tagcaaaagc tgtacaggga accttcagca
     3541 gagtccaatg tactcctgat ctgctgccta gtgatattct tggtttttcc gtatacaatt
     3601 cacaatcaaa agagtttgaa tttcgtccgg gaccgatctt taccacgatc ttgttagcag
     3661 atgagatcaa tcgtacgact cctcgtactc agtcagcact tttagaagca atggccgaga
     3721 atcatgcaac gatcgacaac aatacatacc ctctagacaa tcattttttt gtcttagcta
     3781 cgcaaaatcc aatcgagtac gaaggaacat atcctttgcc ggaagcacag ctcgatcgtt
     3841 ttttattccg actacaaatc ggttatcctt cttttgatga cgaacttttg ctacttttgg
     3901 ataaattcga aaaagtgttg gataacttaa atgaagtatt gaacagttat gaaatagaag
     3961 aaataaaaac aaatgtggcg aatgtctttg tcagtcccga agtggcatct tatgccttgc
     4021 agttagtgtc agcaacaaga agtcatgctg ccatccagct tggcatcagt ccacgaggaa
     4081 gcctttcctt tattcaggca gcaaaagctt atgctttaat ccatgggaga aattacgtca
     4141 cgcccaaaga tttgcaggat ttagttcctt acgtgttttc ccatcgcctg attttttacg
     4201 atcgttcatt gaaggaagac gaaaagaaac aaatcattca tactcttgtt gcacaaattc
     4261 ctattcctgt gaggtagatt gaggtagaca atggaaaaaa tcaaagatta tttcattaat
     4321 tttgtgttat ttctggtata tttcatcatt gtgctttttg ctcttgtatt caacaattct
     4381 ttaggctggt tcttgttggc cttttttact ctttatgtat catggagctt gatttcatta
     4441 agcagctttc taaagaaact ttcggttact tgtacattgc agccactcgt ttatcgcaaa
     4501 aaaagtatgc aggttatttt ttccatagca aaaaagagaa ctttttcttt acctctccct
     4561 cgtttacaaa tcggcttccc agcaatcttt gcagaaaaaa acaagagatt ttgattctta
     4621 caaataaacc gcaagaagtc caattgcttt ggcagccaaa agaaagagga tgccatgaaa
     4681 cattaactgt catttttaca gcctatgata gtctaggact tttcagaaaa agtgcaaaaa
     4741 gagagatctc ttttcctgtg actgttctgc ctgctttttg taagattcaa gcagaaaaat
     4801 tacagagagt tctggaaaaa aaacagcagc tgaacgcgta ccaaagaggt cttgattttc
     4861 gggaacatcg cgcttatcgt ccaggtgatt ctttcaaccg aatcgattgg aaattgtctg
     4921 ctcatactca agagtggtta taccgtgaat acgattatca agaagaagaa tgttctcctc
     4981 ttttttgctt ttggggttcg cccagtccaa aatttgaacc tctgctagac ttgtattttt
     5041 ctttatggca tttgagaaaa gaaaagcagc cggaacttct gatattaggc aaccgcgcct
     5101 ttcatggcaa agaccccggt catacctatt ttgcttcttt ggaagctggc gatgagaaaa
     5161 cttttttcgc acacttgaaa aaatatgcaa aaaaacaaat cgtcctcttt gttcctgaga
     5221 attctcctga agtctcagaa gctattgaaa cattgtcaaa agatcgaacg gtttatcttg
     5281 tttatttcgt agaaaaacaa ctcatggtcc aagaaaaaga caagatatgt tcattgccag
     5341 gaggtgaatg gattgacgat taaacgggaa aaatggctgc gtggcgttta ctcctttgtg
     5401 atactaagtg taggtgctcc gatatttgta gtagctaatc aattgcaaaa cagctacctt
     5461 cttatcctaa ctattggtgt cctatgcctt attgtctgct gtattcctaa aaaatgggta
     5521 cgtttgctgc tttctttgcc agtaatgata ggttgtttgt ttttatattt tccttcgaag
     5581 acattttcca tattatggat cttacagttt ttttcgtcag ttacagagga attcttccat
     5641 ctatcccaag gtaaacttta ttatttgcca gaaaagacag ctttttttct cataatgttg
     5701 ctgatctatt tatttattac attgaccgtg gattacgact attggtacgc accctttctt
     5761 tctttgatgg cttacttcat gatgcttacc gtttttcgga aaaaagattt actgtacgaa
     5821 atgattgcgg tagtaactgt tttgttcgtg tatctggcag caaggcaatt tttctccatc
     5881 cggttgttgt cgagaaacac tcgattccag tcattgacta cagttctgct tatttgtttc
     5941 ttaactttta gcgctatctt gcctttatat cttccgaaag tacaccaatc tctcgaggaa
     6001 acgagtgaac cgatccgaga atatcttaat gatgaagggc tttatgacac actccatgag
     6061 tatcaattaa ccggaagtgc aagaacaggc ttcagtgaga atgatgaaca gcttggtgga
     6121 cctttatatg ataatggcga agttgttttt acagcgaacc aaaaaggaaa tggctattgg
     6181 aagatcgaaa ataaaaatca ttacaccggt tctggatgaa tagaagatca ggacgcaccc
     6241 atccaaccaa tccaagaatt ccctgttgac atcacgagct accaaaccgt tatagaagac
     6301 aaagaaaaca ttacattgac cctaaaaaaa caagctttct taccttatcc ttatggaaat
     6361 actaccttga ctgatttttc attagctagt ggacaaacgc tttactattt gcctgaaagc
     6421 cagcgattca ttcctgtccc gaatgaatcg acacgttctg caactttaca aacagaaagg
     6481 ttagttttta cgagagaaga attaaaaagc agtcagttaa aagctgatga tttagaaaat
     6541 cagcagacaa atcttcaatt gccaaaaagt ttgcctaaac gtattgagga cttggcggtc
     6601 gaattgacca aaaatgaagc aactttaatt cgtaaagtcg aagctgtcta acagtattta
     6661 aaaacaagcg gaaatttccg ctattccaaa acggataccg ggcatactcc aaaagaacac
     6721 gattatgtgg attatttcct ctttgattca aaagtcggct attgtgacaa cttttcaact
     6781 tctatggtcg tccttcttcg aacacttggt atcccagctc gctggacaaa aggttttaca
     6841 aatgggctca gaacaggcac agataatcaa gggaatgagg aatacagcat tctcaatagt
     6901 catgctcatt cttggccaga ggtatacttt cctggatttg gctggcttcc atttgaacca
     6961 accccttcat ttgccaatcc aatgggttca caaccagttg ctgaaacaac cgaaaccgtc
     7021 cagcctgcta tcgaacaacc aaatgaaagc gaaaatatgg cagaaactat ttccagtgag
     7081 agatctgagg tcattccatc agaagaaaca acactcacac cagcttataa aatcgtctta
     7141 ttcagccttg gagtgtgttt atccgtcttg ttgttctttc tattgttatt cagaaaatct
     7201 ctgcgctgga caagttatct tatctatctt catttttttg cttctactaa tacgattgca
     7261 tatcaaaaac ttcttaaccc tttggaaaca ttggtaccgc gcaaacccgc agaatctttg
     7321 caggaatata gcctgcgaat agaacaagaa ttcaagctag atctgcgttt cattcgatta
     7381 actactcaat atgaagcaga aatatatgga cgacaagcag atccggtaaa attcgataaa
     7441 aaaacctatt tagaaataac gcatataata agaaaaacgg tatacaaaaa aattctgaca
     7501 aaagggagcc gcttcaaaaa ataagataaa atttctggag aatctacttc tcgaatgccg
     7561 agaaccagct gattgagtat cgattactcg aaaaaaaggt tgtgacacgt tttttgtcac
     7621 aacct
//
LOCUS       DAFBVQ010000091         7595 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.095, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000091 DAFBVQ010000000
VERSION     DAFBVQ010000091.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7595)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7595)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7595
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.095"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(939..1352)
                     /locus_tag="LLC22_002574"
     CDS             complement(939..1352)
                     /locus_tag="LLC22_002574"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291922.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Hsp20/alpha crystallin family protein"
                     /protein_id="HBK5435791.1"
                     /translation="MANVPSIRDMFPDFNDVFSPAFNDFLGVSSYPKVDLVENEKEYK
                     LTADMPGCDKEDTTVEYSDNTLTISANHESHTEDKEDGNYVRKERHSVSYKRSFYLPN
                     VDEEKITGTFKNGVLKLVLPKTAYQPKETKKIELN"
     gene            complement(1808..2293)
                     /locus_tag="LLC22_002575"
     CDS             complement(1808..2293)
                     /locus_tag="LLC22_002575"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303864.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435792.1"
                     /translation="MHKGIYAGLLGTVILFSACGYKTKNSVKESSAAISTTEVGSTKS
                     TSTTSITNTSTGNVDSQHSQSSIQSFSISSTSEMQESTVPSLPLENSDKALLFLIAHR
                     SELQSDDIVISFYQKIDRDYLFTASSKQIRSQGGSGSVGFYRVSPEGSITMTDANGTP
                     F"
     gene            complement(2432..2677)
                     /locus_tag="LLC22_002576"
     CDS             complement(2432..2677)
                     /locus_tag="LLC22_002576"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305631.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF378 domain-containing protein"
                     /protein_id="HBK5435793.1"
                     /translation="MFYHLRKENSNENLDAIALTLLIVGGLNWLLVGLFELDLVAMIA
                     GGSTTIFAKIIYIVVGICAIYCLKFFPMITRKVDERY"
     gene            2870..3670
                     /locus_tag="LLC22_002577"
     CDS             2870..3670
                     /locus_tag="LLC22_002577"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631871.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5435794.1"
                     /translation="MSDWLDIAGKVVIVTGGSSGIGRSIVENLLKQNAQVANFDVTEC
                     RIQHENLLSLKVDVSSKTDIEEGIYKVMKHFKTIDGLVNNAGINIPSLLIDRNHPKSK
                     YELSEQVFDKMIAVNQKSVYLMSQAVGRILVQKGSGVIVNLSSESGLEGSEGQSCYAA
                     TKAAMNSFTRSWAKELGKRNVRVVGVAPGILEETGLRTQEYEEALSYTRGISVEQLRN
                     GYSRTSTIPLGRSGKLQEVADLVCYYLSERSSYITGVTTNISGGKTRG"
     gene            3689..5557
                     /locus_tag="LLC22_002578"
     CDS             3689..5557
                     /locus_tag="LLC22_002578"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5435795.1"
                     /translation="MTLVNRWYQLLKLLVTHKKVSIQEVQKEIKTSNQTIKKDIGELN
                     EEIAGIAKIIQKNKHFELEIYDFDFFDEIMQGKLKTASDFNSASKRIAYLLNRLIETE
                     DFLRMDDLSEEVGVSRGTVVKDLKTLKEMINDFDVKITGTPNKGLRIIGDELELRLLL
                     FYFVSPYFSETKTEQFLEEKQAIKHFQKKTNASKQEITLLTKVIGISLNRISSNYLLK
                     KPINRYSGCFEYIQEFNELINQLEEIYELTLSQYEKDFISFPLNIINTSITMIRKANS
                     DLRLYFDPMMMRIRRLDLIDLDESFLYQEMKQHLSLLINRVIFRYRLTDLFYGEIEKK
                     YPFSYQIASECIQALEAILQHKISKVEISYLTLYLELAFRYQKEHFSSKKVAIVHTTG
                     KGTALMIQRQIKRILGRDIQITHVSEEQYEKVDLNKYFAVFTTIPLKNVNEETPVIHL
                     TNLFDDSWLRAQWQKAKKKRLAGFHSTVFFYQIWKEKKTYQEYLNKLVAPLIRGYYVD
                     EEFEKRILKREYQQSTFVNKEFAFPHTTNQLSQHIVLSVGLITDQGLAETGGNAVIFL
                     FAIPEEMTAEVENELFELYDILFELIKMGIDEFIELAPTQESFLKLIKSKGERLHE"
     gene            5550..6041
                     /locus_tag="LLC22_002579"
     CDS             5550..6041
                     /locus_tag="LLC22_002579"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390786.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DeoR family transcriptional regulator"
                     /protein_id="HBK5435796.1"
                     /translation="MNDMYLFIVFAASAYVLQAVISWKQLKHFNQTYSELRRKGKVAI
                     GKRPGKIRSGTIVMLAIDDHDQVLEVRKMQGVTSLAKFHSLPVYAGEDIHYIDRYHPS
                     VRAEDRLTQAALENAREVYLRIEAGNEKSEQPSLPFIAMLNNFRIWKSTIKEKRSDKR
                     WIS"
     gene            6029..6583
                     /gene="srlA"
                     /locus_tag="LLC22_002580"
     CDS             6029..6583
                     /gene="srlA"
                     /locus_tag="LLC22_002580"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002327877.1"
                     /note="catalyzes the phosphorylation of incoming sugar
                     substrates along with their translocation across the cell
                     membrane; the IIC domain forms the PTS system
                     translocation channel and contains the specific
                     substrate-binding site; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIC"
                     /protein_id="HBK5435797.1"
                     /translation="MDIITKFAEGFMRLFQTGAETFISWMTGIVPVVLMLMVAMNTLI
                     AFLGEDRVTKVAKLSAKNPLTRYLVLPFLSAFMLGNPMSFTMARFLPEYYKPSYYAAQ
                     AQFCHTSNGVFPHINPGELFVWMGIAQGIETLGLNSMELAIRYLLVGLLMNFIGGWIT
                     DFTTGFVCRQQGIVLSKKVELSVD"
     gene            6601..>7595
                     /locus_tag="LLC22_002581"
     CDS             6601..>7595
                     /locus_tag="LLC22_002581"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299265.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucitol/sorbitol transporter subunit IIB"
                     /protein_id="HBK5435798.1"
                     /translation="MYGDIKIVRGNGGYGGPLIIRPTKDKHKFIYVTGGGERPMIVDK
                     IEELTGMESINGFKTSIPDSEIALAIVDCGGTLRCGIYPKKGIPTINIVPTGKSGPLA
                     QYITEDIYVSAVGLEQIQPLMETDDNKETVNTASPDKKYKYDTSKKITEQKAEQQNWI
                     AKIGMGAGKVVATFNQSAREAVDTMIRTVIPFMAFVSLLIGVIQGSGIGNVFANIMAP
                     LAGNAVGLTIIGFICSLPFLSPLLGPGAVISQVIGTLIGVEIGKGNIPPQLALPALFA
                     INTQNACDFIPVGLGLEEAKAETVEVGVPSVLYSRFLNGIPRVIIAWVASFGLYS"
BASE COUNT         2706 a         1215 c         1441 g         2233 t
ORIGIN      
        1 ttactatgaa taacataata agaaagtaaa gtggattgat ttgagatctt tttatacttc
       61 aaaaaagata acacccaact ttcaaaaata tgttttggaa gttgggacaa acgagttaat
      121 acattttaat acattatttt ttattcaaaa aaaatagcac aatggcaaag atcgtaagag
      181 agatcataag ccccaatgaa tgactaaaaa gaaaagcaga atcacatgcc atatcatccc
      241 atatttcttc aagaaaataa ataagcggga aaaagggaag gaatagtaga acatcgatcc
      301 agcaccattt ttttcttctt ttgaaataac ataaaacaat aaacatgaac gtgcagggaa
      361 gtaaaaacaa agctttactc ataactaaca aaataccagc tccttttatt tttttctccc
      421 ccacattcaa agagtaacaa tggtatgtac ttaataatag aaaaatggat caacttgtat
      481 gaataacagc tgaaaagatc tgcaccaaat aaaaaacttc cagccaaaac tgactggaag
      541 tttatttttt tctgaaatat tctaacacaa atatgaaaaa gatggccgaa gctaataagc
      601 cgatttcgta gcaaaacaat gagataccag agtcgtaata ataaaatcct ctaatcttat
      661 ggataaaata gatcatcgga caagcagata agagtaagta tttgttaggc cttttgaata
      721 agtaaaagaa agcactggtc attatgataa atggtatcca aaacaaaagt ttacttaaga
      781 caatcaaatg atcaactccc atatttttta ccaagagaga tcataacatc tttatcgtaa
      841 aaacaaaata tttttttgct cattttgaaa atttaaacat actcgttctt atccaaatat
      901 ataaaaatcg cccctcattc atcgagaggc gataagttct aatttaactc aatttttttt
      961 gtttcttttg gctgataagc tgttttaggt aataccaatt tcagcacacc gtttttaaag
     1021 gttccagtga ttttttcttc atcaacatta ggaagataga atgaacgttt gtaagagacc
     1081 gaatgtcttt ctttccgtac atagttgcca tcttctttat cttctgtatg ggactcatga
     1141 ttggcggaga tcgtcaaagt attatctgaa tattcaactg tcgtgtcttc tttgtcacag
     1201 ccaggcatat cagcagttag tttgtattct ttttcatttt cgactaaatc tacttttgga
     1261 taacttgaaa cacctaaaaa atcattgaat gctggactaa acacgtcatt gaaatcaggg
     1321 aacatgtcgc gaatgctagg tacatttgcc atttttgatc atcctttcaa taagtatttt
     1381 ttatttatcc ctatttacgt aataactcta ttttgaaaaa aatgcaagta taatggttag
     1441 ctttgtgaat atttcatcta atacgataca aaggctatct ttctaatttg aaaaagggat
     1501 cattaaaata ataagaagaa aatatgtcaa aaggtaaaaa agtaaattct tctatccaaa
     1561 tatagaaaaa ttgaatctag aaaaccgccc gacaataaat ttcattaact cagttgaccg
     1621 aaaatgaagt agataccaaa aatttatcaa gagagcaagt agagaagtga gtatattcat
     1681 aagagaaata gctgtaacga attattaggt taatgcaaat gcttatttat actccgtata
     1741 actttctcag aaaaaatgat accaataatg acttgctagt actgtaaatc cgtataatat
     1801 catctaatca aaatggtgtt ccatttgcat ctgtcatcgt aatcgatcct tcgggtgaca
     1861 ctcgataaaa accaacgctt ccagatcctc cttgggaacg gatttgtttg ctggaagctg
     1921 tgaacaaata atctcgatca attttttgat aaaagctaat aacaatatcg tcactttgta
     1981 attcggaacg gtgggcaata agaaatagaa gtgctttgtc agagttttct aatggaagag
     2041 aaggtacagt gctttcttgc atttcagatg ttgaagaaat gctaaacgac tgaatacttg
     2101 attggctatg ttgcgaatct acattaccag tagaagtatt agtaatggaa gtagtagaag
     2161 tacttttagt tgaaccaacc tcagttgttg aaatggctgc tgaagattct ttaacagaat
     2221 tctttgtttt atatccacag gcagaaaaaa gtattacagt tcccaacaag cctgcgtaaa
     2281 tccctttatg catgatagct cctcctaaaa tagattatct ttattcagta tatcacttaa
     2341 acaaagaaaa gcagatggtt taaaatgaaa aaaccttccc aataaaggga aggttcatga
     2401 agataataac ttttttaata attatagctt tctaatatct ttcatcaact tttctagtaa
     2461 tcattgggaa aaatttcaag cagtagatcg cacaaatacc tacgacgata taaatgatct
     2521 tcgcaaaaat agttgttgaa ccaccagcaa tcatagctac taaatcaagt tcgaacaagc
     2581 ctaccaacag ccagttcaac cctcccacaa tcaataaagt taatgcaata gcatctaagt
     2641 tttcattaga attctccttt cttaaatgat aaaacaatta tatatcaaaa agagaaacat
     2701 tgcttatata acgctcagga attttagcaa tctatgcaaa aagatgaaaa ttttttttgc
     2761 tcttccatta gtacacattt tttagctgaa gctgtaaatt tcatgtctta atttttttta
     2821 gtgagctttt atactggatt tgtaagaaaa aagaaggaga ggatcacata tgtcggattg
     2881 gttggatatt gcaggaaaag tagtaattgt aactggaggt tcctcaggaa ttggaagaag
     2941 tatcgtcgaa aatttgttga agcagaatgc acaagtagcg aattttgatg taactgaatg
     3001 ccgtatacag catgaaaacc tactatcttt aaaagtcgat gtgtcttcta aaacggacat
     3061 agaagaaggg atatataaag taatgaaaca tttcaagacg atcgatggtc tagtcaataa
     3121 tgcaggaata aatattcctt ctcttctaat agatagaaat catccaaaaa gcaagtatga
     3181 attatcagaa caagtttttg ataagatgat cgctgtcaat caaaaaagtg tatatttgat
     3241 gagccaagca gttggaagaa tcttggtgca aaagggatca ggagtgatcg tgaatctttc
     3301 ttctgaatca ggattggaag gatcagaagg acagagctgt tatgctgcta caaaagcagc
     3361 gatgaacagt tttactcgtt cttgggcaaa agagttagga aagaggaatg ttcgtgtggt
     3421 aggtgttgca ccagggatac tggaagaaac cggtttgaga acacaagaat atgaagaagc
     3481 tctttcttat acgagaggta taagcgtcga acagctgaga aacggttaca gtcgaacaag
     3541 tacgatccct ctaggaagga gtggtaagct gcaagaagtg gcggatctag tctgctatta
     3601 tctttcagaa agatcaagtt atatcactgg agtcacgact aatatttcag gaggtaaaac
     3661 aagaggataa aggatagggg ggacgcacgt gacgctagta aacagatggt accaattatt
     3721 gaaattacta gtcactcaca agaaagtttc aatccaggaa gtgcaaaaag aaatcaaaac
     3781 cagtaatcaa accataaaaa aagatattgg ggagttgaat gaagaaattg ccggtattgc
     3841 aaaaatcatc caaaaaaaca aacattttga acttgaaatt tatgattttg atttttttga
     3901 tgagatcatg caaggaaaat tgaaaacagc cagtgatttc aattcggcat ccaaaagaat
     3961 cgcttattta ctaaataggc tgatcgaaac agaggatttc ttacgtatgg atgatttgtc
     4021 tgaagaagtc ggtgtcagca gaggaacagt ggtcaaggat ctaaagacat taaaagagat
     4081 gatcaatgat tttgatgtaa agattacagg cacaccaaat aaaggactaa gaataatagg
     4141 agatgagcta gaattacgac tacttttatt ttattttgtt tctccctact tttcagagac
     4201 gaaaacagaa cagtttctag aagaaaaaca agcaatcaaa cattttcaga agaagacgaa
     4261 tgctagtaaa caagaaatca cccttttaac gaaagttatc ggtatttctt tgaatagaat
     4321 ctctagtaac tatctgttga agaagcccat caatcgttac agtgggtgtt ttgaatatat
     4381 ccaagaattc aatgaactga tcaatcagtt ggaagaaatc tatgaactaa ctttgagcca
     4441 atatgaaaaa gattttatca gttttccttt gaacatcatc aacacaagta taacgatgat
     4501 aaggaaagct aactctgatt tgcgcttata tttcgacccc atgatgatgc gtattcgacg
     4561 attagatctc attgatctgg atgagtcctt cttatatcaa gagatgaaac agcacctctc
     4621 tttattgata aatcgggtaa tttttcgtta tcgattgact gatttatttt atggtgagat
     4681 agaaaaaaag tatccttttt cttaccaaat cgctagcgaa tgcatacaag cattagaagc
     4741 tatcttgcaa cataagatct ctaaagtaga gatcagctac ctaacgttgt atttggagtt
     4801 agcatttcga tatcaaaaag agcatttttc ctctaaaaaa gtagccattg ttcatacgac
     4861 aggaaaagga acagcattaa tgatccaaag acaaatcaaa aggatattgg ggagggatat
     4921 acaaataaca catgtttcag aagaacaata tgaaaaagta gatctaaaca aatatttcgc
     4981 tgtttttaca acgattccgt taaaaaatgt aaatgaagag acaccggtga tccatttgac
     5041 taatcttttt gatgactctt ggttaagggc acaatggcaa aaagcaaaaa aaaagcgatt
     5101 agccgggttt cattctactg tttttttcta tcaaatatgg aaagaaaaaa agacgtatca
     5161 agaatattta aacaaattag tcgctccttt gatcagaggc tattatgtgg atgaagaatt
     5221 tgaaaaaagg atcttgaaaa gagaatatca gcaaagcaca tttgttaaca aagaatttgc
     5281 ttttcctcac acaaccaacc agctatctca acacattgtt ttatcagtag ggctaataac
     5341 tgatcaaggt ttagcagaaa caggaggaaa tgcagttatt tttttatttg ccatacctga
     5401 agaaatgacg gctgaagttg agaatgaatt atttgagcta tacgatatcc tatttgaact
     5461 cataaaaatg ggaatagatg agtttattga attagcaccg acacaagaat catttttaaa
     5521 actaatcaaa agtaaaggag agagacttca tgaatgatat gtatctattc atagttttcg
     5581 cagcttcagc ttatgtgctg caagcagtta tcagttggaa gcaactaaag catttcaatc
     5641 aaacatatag cgaactgcga agaaaaggaa aagtagcgat tggtaaacga cctgggaaaa
     5701 tccgttcagg cacgattgtt atgctagcta tagacgatca tgatcaagtt ttagaagtca
     5761 gaaaaatgca aggggttaca tctttggcaa aatttcattc attacctgtc tatgcgggtg
     5821 aagatatcca ttacatcgat cgttaccatc cctcagttcg agcggaagat cgtttgacac
     5881 aagcagcttt agaaaatgcc agagaagtat acttacgaat agaggcagga aatgaaaaaa
     5941 gtgaacaacc ttcattgcct tttattgcta tgctcaataa ttttcggata tggaaaagta
     6001 cgatcaaaga aaaaaggagt gacaaacgat ggatatcata acaaaatttg ctgagggatt
     6061 tatgaggctg ttccaaacag gtgcagaaac attcataagc tggatgacag gaatcgtacc
     6121 agttgtcttg atgctgatgg ttgcaatgaa tacgctgatt gcttttttag gtgaagaccg
     6181 agtaacgaaa gtagccaaat tatcagcgaa aaatccgctt actcgttacc ttgtgttacc
     6241 gttcttatct gcttttatgt tgggaaatcc tatgtcattt acaatggctc gtttccttcc
     6301 agaatactac aaaccaagct attatgctgc tcaagctcaa ttttgtcata cgagcaatgg
     6361 tgtattcccc catattaatc ctggagaatt gtttgtatgg atggggattg ctcaagggat
     6421 cgaaacctta gggctaaatt cgatggagct ggctatccga tacttgcttg tgggactgct
     6481 gatgaacttt attggtggtt ggataactga ttttactact ggatttgtat gcagacagca
     6541 aggaatcgtt cttagcaaaa aagtagagct ttcagttgat tagagaaagg agagttttaa
     6601 atgtatggtg atattaagat cgtaagagga aacggcgggt atggaggtcc tttgattatt
     6661 aggccgacaa aagataaaca caagttcatc tatgtcacag gtggaggtga gaggccaatg
     6721 atcgtagata aaatagaaga actgacaggt atggagtcta tcaatgggtt caaaacatca
     6781 atacctgata gtgaaatcgc gcttgcaatc gttgactgtg gagggactct tagatgtgga
     6841 atttatccta aaaaagggat accaaccatc aatatcgttc ccacaggaaa aagtggccca
     6901 ttagcacaat atatcactga agatatttat gtttcagcag tagggttaga acaaatacag
     6961 ccactaatgg aaactgatga taacaaagaa acagtaaata ctgcatctcc agataaaaag
     7021 tacaaatatg atacttctaa aaagataacc gagcaaaaag cagagcagca aaactggata
     7081 gcaaaaattg gaatgggcgc gggaaaagta gttgctacat tcaatcaatc agcaagagaa
     7141 gcagtagata cgatgatccg gacagtgatc ccttttatgg ctttcgtttc ccttttgatt
     7201 ggtgtgatac aaggttctgg gatcggtaat gtatttgcta acattatggc acctttagca
     7261 ggaaatgcag ttggattaac aatcattggc tttatttgtt cactgccatt tttatctcct
     7321 ttgcttggtc caggggcagt tattagccaa gtgattggaa cattgatcgg tgtagagatt
     7381 gggaaaggaa atattcctcc ccaattagca ttaccggcac tatttgctat caatactcaa
     7441 aatgcatgtg attttattcc agtcggtcta ggtttggaag aagcaaaagc tgagacagta
     7501 gaagtaggtg taccatcagt tctttattca agatttctta acggcatccc acgagttatc
     7561 attgcttggg tagcaagttt tggattatat agctg
//
LOCUS       DAFBVQ010000092         7398 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.097, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000092 DAFBVQ010000000
VERSION     DAFBVQ010000092.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7398)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7398)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7398
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.097"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            70..153
                     /locus_tag="LLC22_002582"
     CDS             70..153
                     /locus_tag="LLC22_002582"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBK5435799.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            278..1015
                     /gene="erm(B)"
                     /locus_tag="LLC22_002583"
     CDS             278..1015
                     /gene="erm(B)"
                     /locus_tag="LLC22_002583"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBK5435800.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1185..1445
                     /locus_tag="LLC22_002584"
                     /pseudo
     CDS             1185..1445
                     /locus_tag="LLC22_002584"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1608..2273
                     /locus_tag="LLC22_002585"
                     /pseudo
     CDS             1608..2273
                     /locus_tag="LLC22_002585"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2309..2554
                     /locus_tag="LLC22_002586"
     CDS             2309..2554
                     /locus_tag="LLC22_002586"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5435801.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2657..3526
                     /locus_tag="LLC22_002587"
     CDS             2657..3526
                     /locus_tag="LLC22_002587"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBK5435802.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3507..4241
                     /locus_tag="LLC22_002588"
     CDS             3507..4241
                     /locus_tag="LLC22_002588"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5435803.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4274..5182
                     /locus_tag="LLC22_002589"
     CDS             4274..5182
                     /locus_tag="LLC22_002589"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBK5435804.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5179..5721
                     /gene="sat4"
                     /locus_tag="LLC22_002590"
     CDS             5179..5721
                     /gene="sat4"
                     /locus_tag="LLC22_002590"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBK5435805.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5814..6608
                     /locus_tag="LLC22_002591"
                     /note="aph(3')-IIIa"
     CDS             5814..6608
                     /locus_tag="LLC22_002591"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBK5435806.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6884..>7398
                     /locus_tag="LLC22_002592"
     CDS             6884..>7398
                     /locus_tag="LLC22_002592"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001079940.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5435807.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMI"
BASE COUNT         2591 a         1117 c         1555 g         2135 t
ORIGIN      
        1 tttgtgtata ataggaattg aagttaaatt agatgctaaa aatttgtaat taagaaggag
       61 ggattcgtca tgttggtatt ccaaatgcgt aatgtagata aaacatctac tgttttgaaa
      121 cagactaaaa acagtgatta cgcagataaa taaatacgtt agattaattc ctaccagtga
      181 ctaatcttat gactttttaa acagataact aaaattacaa acaaatcgtt taacttctgt
      241 atttatttac agatgtaata acttcaggag tgattacatg aacaaaaata taaaatattc
      301 tcaaaacttt ttaacgagtg aaaaagtact caaccaaata ataaaacaat tgaatttaaa
      361 agaaaccgat accgtttacg aaattggaac aggtaaaggg catttaacga cgaaactggc
      421 taaaataagt aaacaggtaa cgtctattga attagacagt catctattca acttatcgtc
      481 agaaaaatta aaactgaaca ttcgtgtcac tttaattcac caagatattc tacagtttca
      541 attccctaac aaacagaggt ataaaattgt tgggagtatt ccttaccatt taagcacaca
      601 aattattaaa aaagtggttt ttgaaagcca tgcgtctgac atctatctga ttgttgaaga
      661 aggattctac aagcgtacct tggatattca ccgaacacta gggttgctct tgcacactca
      721 agtctcgatt cagcaattgc ttaagctgcc agcggaatgc tttcatccta aaccaaaagt
      781 aaacagtgtc ttaataaaac ttacccgcca taccacagat gttccagata aatattggaa
      841 gctatatacg tactttgttt caaaatgggt caatcgagaa tatcgtcaac tgtttactaa
      901 aaatcagttt catcaagcaa tgaaacacgc caaagtaaac aatttaagta ccgttactta
      961 tgagcaagta ttgtctattt ttaatagtta tctattattt aacgggagga aataattcta
     1021 tgagtcgctt ttttaaattt ggaaagttac acgttactaa agggaatgga gataaattat
     1081 tagatatact actgacagct tccaagaagc taaagaggtc cctagcgcct acggggaatt
     1141 tgtatcgata aggggtacaa attcccacta agcgctcggg accccttgta ggaaaatgtc
     1201 ctaagtgtgg caacaatatt gtattaaaaa aatcgtttta tggttgttca aattatcctg
     1261 aatgtaagtt tactttagct gaacatttta gaaagaaaaa actaaccaaa acgaatgtaa
     1321 aagaattact ggagggaaaa gaaaccctgg taaaaggaat caaaaacaaa gagaaaaagc
     1381 cctacaatgc cgttgtaaaa attggggaaa agggatatat tgattttatc tctttttcaa
     1441 aataaacatg gggctgaccc aaaagtagct cctatatgaa aaatagaggt ctttccattt
     1501 agatagtagt ggaaagacct ctatttatct tttgaaagtg aatacaaaaa taaagcacac
     1561 tctgctataa tataggtgat taatccattt gagagaggtg ctttatcatg tatcaaaatt
     1621 ataccataaa ccaactttgt ttgcctatag atcttgaaat taaattggaa gaaaatgatt
     1681 ttgctcatgc cattgtgcag tttgttgact ctattcccga tgaagtcttt cttccttatt
     1741 atcaatctat gggtagaccc caatatcatc ctcgtatgct actttccatt attctttgtg
     1801 cctatattca aggggtttat tcgggccgcc aaatacaaaa tatgctgata gatagtattc
     1861 ggatgcgcta cttatctcaa gagcaattcc ctaactttcg tactattaat cgttttcgcg
     1921 ttcatccgat tatgaacgat attctagatc attcatttgt tcaatttcgt gagctactgg
     1981 ttcaaagtgg cttaatcagt ggcagtgctc tatacattga tggtacaaaa attgaagcgg
     2041 atgcgaataa atactctttc gtttggaaaa aaagtatttt aaagtataag gatagccttg
     2101 atcaaaaagc ccttgaaaac taccaacaaa tggtggaaac aaaaatctta cctgagttaa
     2161 tagatgattt aaaggatgaa ctttctatag aagagattga aaggattcgt caatctttgg
     2221 aagaaaagga aaatcaatta attgaagcga ttgaccaaac cgaaacagta gaagggggct
     2281 gacccattat taataaggag tggacaacat gattgatgta aatgagctat tggaagaagc
     2341 tattagagaa actgaaaatc taaatgatgg cgaagttttt cttgttaaag atttattcaa
     2401 gggatatgtg gggaatagga tacccagaaa ggatcgactt ctgcttggaa cgttattttt
     2461 aaaccatgtt agcaaaatga atggtaattt aaaggctatt gaaaagactt catctaatca
     2521 gcagaggtat aaaaagacaa ttgataagtt ttaactatct tttgtgaaat taaaaaaatt
     2581 ataaatatgt tgagtagaag caaaagattt ggcttggaat ttttacagca gtgaatcgat
     2641 aaaaggagca tgcttgatgg tagataatat tattaaatca gtagcagaga aattatcctc
     2701 tctgtcttat atagaaggta ttgttttagg tggttcacgt gcaaggggca cccatacaga
     2761 ggattcggat atagatatcg gcatctatta caattcagaa tcatttgaca taaatactat
     2821 taatcaattc gctacaaagc tggatgatga gcatagaaat aaccttgttg tacctcccgg
     2881 agcatggggt gattggatta atggcggcgg atggttagtc ataaacgggt atcatgtgga
     2941 tttaatttta cgtgatatta aacgtgtgga acaaataatg aaagatacag agcacggaat
     3001 tgttactgcc aattatcaga ctgggcatcc ccatggttat attagtgcaa tgtatcgagg
     3061 agaattagcg attagcaaaa tactatatgc taagaatgaa agcttatgcg aattaaaaaa
     3121 acaggcagaa acttatccca atgctttgca gaaaagttta gttaactttt ttatgtttga
     3181 agcagggttc tctttaatgt ttgtaaaagc aaattcggga acagacgata aatattatat
     3241 tgcgggtcat gtttttcgta tagtttcatg tttaaatcaa gtgttatttg catgtaataa
     3301 tgcttattgt atcaacgaaa agaaagctat aaaactgctt gaaacttttg aacataaacc
     3361 tgaaaaatat accgagaagg taaatcatat ttttgaagta ctcggtatct cactttttga
     3421 atgctacgac atgaccgaga agctttataa tgaagtgaat gaaattgtat cggagataaa
     3481 taacttttta aacgaggaga gttcagatga aagaaaacaa atatgatgat aatatatttt
     3541 ttcaaaaata cagtcaaatg agtcgctcgc agaaaggact ggctggtgcg ggagaatggg
     3601 agactttgaa aaagatgcta cctgatttta agggtaagcg tgtgcttgat ttaggatgcg
     3661 gctatggatg gcactgtata tatgcgatgg aaaacggtgc ttcctctgta gtaggtgttg
     3721 atatttctca taaaatgctc gaagtagcaa aaggaaaaac ccattttcca cagattgaat
     3781 atgaatgctg tgccatagaa gatgtggatt tcccagagga gagctttgat gtaatactaa
     3841 gttcgcttgc gtttcattat gtagcagact atgagaattt aataaaaaag atatatagga
     3901 tgctgaaggc tggtggcaat ttagttttta cagttgaaca tcctgttttt actgctcatg
     3961 gaacacaaga ctggtattat aacgaaaaag gagaaatact gcatttcccg gtggacaatt
     4021 attattatga gggcaaacgg acagctatgt ttttggaaga aaaggttaca aaatatcata
     4081 gaacactgac cacatatcta aatacactgc tttcaaatag ttttataata aatcagattg
     4141 tggagccaca gccgccagag aacatgatgg atattccggg gatggcggat gaaatgcgac
     4201 gcccaatgat gctgattgta tcggcaaaaa agaagatgta ataatataga aaaaataaac
     4261 gaggagtatg taaatgagat cagaaaaaga aatgatggat ttagtacttt ctttagcaga
     4321 acaggatgaa cgtattcgaa ttgtgaccct tgaggggtca cgcgcaaata ttaatatacc
     4381 taaagatgaa tttcaggatt atgatattac atattttgta agtgatatag aaccgtttat
     4441 atctaatgat gactggctta atcaatttgg gaatataata atgatgcaaa agccggagga
     4501 tatggaatta ttcccacctg aagaaaaggg attttcctat cttatgctat ttgatgatta
     4561 caataaaatt gatcttacct tattgccctt ggaagagtta gataattacc taaagggcga
     4621 taaattaata aaggttctaa ttgataaaga ttgtagaatt aaaagggaca tagttccgac
     4681 tgatatagat tatcatgtaa gaaagccaag cgcaagggag tatgatgatt gctgcaatga
     4741 attttggaat gtaacacctt atgttattaa aggattgtgc cgtaaggaaa ttttatttgc
     4801 tattgatcat tttaatcaga ttgttcgcca tgagctgctg agaatgatat catggaaggt
     4861 cggcatcgaa acaggcttta aattaagtgt aggcaagaac tataagttta ttgaaaggta
     4921 tatatccgag gatttgtggg agaaactttt gtccacctac cggatggatt cctatgaaaa
     4981 catatgggaa gcattatttc tatgccatca attgttcagg gcggtatccg gtgaggtggc
     5041 ggaaaggctt cattatgcct atccggagta tgataggaat ataacaaaat ataccaggga
     5101 catgtataaa aaatacactg gtaaaaccgg ctgcctggat agcacatatg ccgctgatat
     5161 agaagagagg cgggaacagt gattacagaa atgaaagcag ggcacctgaa agatatcgat
     5221 aaacccagcg aaccatttga ggtgataggt aagattatac cgaggtatga aaacgagaat
     5281 tggaccttta cagaattact ctatgaagcg ccatatttaa aaagctacca agacgaagag
     5341 gatgaagagg atgaggaggc agattgcctt gaatatattg acaatactga taagataata
     5401 tatctttact accaagacga taaatgcgtc ggaaaagtta aactgcgaaa aaattggaac
     5461 cggtacgctt atatagaaga tatcgccgta tgtaaggatt tcagggggca aggcataggc
     5521 agcgcgctta tcaatatatc tatagaatgg gcaaagcata aaaacttgca tggactaatg
     5581 cttgaaaccc aggacaataa ccttatagct tgtaaattct atcataattg tggtttcaaa
     5641 atcggctccg tcgatactat gttatacgcc aactttgaaa acaactttga aaaagctgtt
     5701 ttctggtatt taaggtttta gaatgcaagg aacagtgaat tggagttcgt cttgttataa
     5761 ttagcttctt ggggtatctt taaatactgt agaaaagagg aaggaaataa taaatggcta
     5821 aaatgagaat atcaccggaa ttgaaaaaac tgatcgaaaa ataccgctgc gtaaaagata
     5881 cggaaggaat gtctcctgct aaggtatata agctggtggg agaaaatgaa aacctatatt
     5941 taaaaatgac ggacagccgg tataaaggga ccacctatga tgtggaacgg gaaaaggaca
     6001 tgatgctatg gctggaagga aagctgcctg ttccaaaggt cctgcacttt gaacggcatg
     6061 atggctggag caatctgctc atgagtgagg ccgatggcgt cctttgctcg gaagagtatg
     6121 aagatgaaca aagccctgaa aagattatcg agctgtatgc ggagtgcatc aggctctttc
     6181 actccatcga catatcggat tgtccctata cgaatagctt agacagccga ttagccgaat
     6241 tggattactt actgaataac gatctggccg atgtggattg cgaaaactgg gaagaagaca
     6301 ctccatttaa agatccgcgc gagctgtatg attttttaaa gacggaaaag cccgaagagg
     6361 aacttgtctt ttcccacggc gacctgggag acagcaacat ctttgtgaaa gatggcaaag
     6421 taagtggctt tattgatctt gggagaagcg gcagggcgga caagtggtat gacattgcct
     6481 tctgcgtccg gtcgatcagg gaggatatcg gggaagaaca gtatgtcgag ctattttttg
     6541 acttactggg gatcaagcct gattgggaga aaataaaata ttatatttta ctggatgaat
     6601 tgttttagta cctagattta gatgtctaaa aagctttaac tacaagcttt ttagacatct
     6661 aatcttttct gaagtacatc cgcaactgtc catactctga tgttttatat cttttctaaa
     6721 agttcgctag atagagttct atattagaga tgtaaagagt tttggtgaag aggtttgtga
     6781 gtatggcttt tataaccagg gtgcaatgag aagcactaac agcagctagc ttaagaacgc
     6841 ataggatata ctttttatgg aagtcacaga ggaggaataa aatttgaaca ggattaacag
     6901 agtaacctct attcttattc agctgcaatc aaaaaaaata attcctgcca aagaaattgc
     6961 acagcgattt aatataagct taaggacagt ttacagagat atccggacac ttgaagaagc
     7021 cggaatacca attggatctg aggccggaaa aggatatttt cttgtagagg gcttcctact
     7081 tccgccggta atgtttacag cggcggaagt gggtgcattg attacagcag ggaaattttt
     7141 aaattgccat ggagatgaat catttataaa ggattttgat tcagctatgt ataaaatcaa
     7201 atctattttg aagcatggtg aaaaaaacta tgcacaggag ttggagaaca gtattaacgt
     7261 gtacagcaca tctggacaga aaaatacatt ggcggataac gttattgcag caattcagac
     7321 tgcaatctgc aataaaaggg taatatcaat tcaatatcct gcatcaggag ggcaagaacc
     7381 ggaaagcaga atgataga
//
LOCUS       DAFBVQ010000093         6962 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.098, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000093 DAFBVQ010000000
VERSION     DAFBVQ010000093.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6962)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6962)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6962
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.098"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..193
                     /locus_tag="LLC22_002593"
     CDS             <1..193
                     /locus_tag="LLC22_002593"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002407829.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435808.1"
                     /translation="GRMSELGYSMMFGEVEKNFFMKHIKGRGYVDTGGSVISEFYTPL
                     VPKGYDFLDSISKLEKMND"
     gene            271..945
                     /locus_tag="LLC22_002594"
     CDS             271..945
                     /locus_tag="LLC22_002594"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297358.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="zeta toxin family protein"
                     /protein_id="HBK5435809.1"
                     /translation="MESNDSYLEYAKANKDKFISYIIKGKSPEVGRDAVFMAGSPGAG
                     KSEVAIGLAENYDNHVIIDADYFRTQFPDYNGKNSSLFQKASSWLVEQAFRYVLDHGY
                     SFILDATFAILSAEKNISRALKKHFRVTIFYVYQDPKIAWKFTQEREIAEGRHVPKKA
                     FINAFFKSRENIAKVKSKHPDVLLHIIIKDYTNNISEVHYATDNLELFLPLGYSRKDL
                     EVQLHD"
     gene            938..1102
                     /locus_tag="LLC22_002595"
     CDS             938..1102
                     /locus_tag="LLC22_002595"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297357.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435810.1"
                     /translation="MTEKEQVTKIVKKYNKSIADLSENATAKEFKTVIKYVADQANEK
                     QRKLVGLNKK"
     gene            1178..2320
                     /gene="dcm"
                     /locus_tag="LLC22_002596"
                     /pseudo
     CDS             1178..2320
                     /gene="dcm"
                     /locus_tag="LLC22_002596"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016613853.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA (cytosine-5-)-methyltransferase"
     gene            2310..2600
                     /locus_tag="LLC22_002597"
     CDS             2310..2600
                     /locus_tag="LLC22_002597"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297354.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435811.1"
                     /translation="MVYDELIGEIYWVIGKIQSDPELEEQLRRLKFDIRKNGVKVAGD
                     PYLMNEETDARIEINQVIAEFERIADQAKEPDIRQYLLEMKAELEVNGITDE"
     gene            2859..4043
                     /locus_tag="LLC22_002598"
     CDS             2859..4043
                     /locus_tag="LLC22_002598"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321708.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5435812.1"
                     /translation="MAQRNLDYRLLKDRRNEYGVSQNKLATACGLSRPYLNQIENGGV
                     TASIKTMRKIFDQLESFNPDLPLTLLFDYVRIRFPTTDARKIIQEILHLKFEYMLHED
                     YAFYSYQEQYVMGDIVVMLSHEEDKGVLLELKGRGCRQFETFLLAQKRSWYDFFEDCL
                     KAGGVMKRLDLAINDRVGLLDIPELTKKCQKEECISLFRTFKSYRSGELLKADEKDGM
                     GNTLYIGSLKSEVYFCLYEKDYEQYIKLGIPLDQTETKNRFEIRLKNDRAFHAIQDLL
                     KGRSIESTTFSIINRYLRFADKVEGKRRTNWPLNEQWGRFIGRNRKEIQLTSEPKPYT
                     IERTLNWLGRQVAPTWKMAKELDRLNRTTYIQDMVQNARLSDRHKKILEQQSMAIENL
                     II"
     gene            4040..4177
                     /locus_tag="LLC22_002599"
     CDS             4040..4177
                     /locus_tag="LLC22_002599"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322329.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3789 domain-containing protein"
                     /protein_id="HBK5435813.1"
                     /translation="MKRGIVMGIVKDIFLVFGGSMLGVTVMCLMNASAAADRAMEKKG
                     K"
     gene            4923..6833
                     /gene="ltrA"
                     /locus_tag="LLC22_002600"
     CDS             4923..6833
                     /gene="ltrA"
                     /locus_tag="LLC22_002600"
                     /EC_number="2.7.7.49"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="group II intron reverse transcriptase/maturase"
                     /protein_id="HBK5435814.1"
                     /translation="MPKNKNETLCVEDLRHAEYYEMQNTFDDLYAKSKNGDIFTHLMD
                     IILSRENILLAYRNIKANAGSKTAGTDGTIIKDIGKLPAETVVKKVRYIVAGSPHGYR
                     PKPVRRKEIPKPNGKTRPLGIPCMWDRLIQQCIKQVLEPICEAKFSENSYGFRPNRSV
                     ENAIKATYNRLQISQLHYVIEFDIKGFFDNVNHSKLIKQIWAMGIRDKHLIFILKRIL
                     KAPIKMTNGTITYPEKGTPQGGIISPLLANIVLNELDHWVESQWQENPVTKNYVVHIN
                     KSGSPCKSNAYKEMKKTKLKEMYMVRYADDFRVFCRYKESAEKAKIAITQWIEQRLKL
                     EVSQEKTRIVNVRKRYSDFLGFKIKMIPRRKKLVVKSHISDKQFKNQKDKLVSQAKKI
                     ASPSKGKTELEETRLYNSMVLGMQNYYQIATNVNLDCMKLNRAVMAIFTNRLGTNKRG
                     RLRKTGRQLTTKEATRYGKSKMLRYVAGEGEPIFPVGYIQHRKPMAKVYLANCYTLEG
                     RKFIHTNLSVDKLLMYQLMKLSLENRTIEYADNRISLFSAQHGKCAITLEEFQQANEI
                     HCHHIVPTGAGGNDDYKNLILVKEAVHRLIHAKTEETIQKYIALLKLNKVQLIRLNKY
                     RVLAGNQELNLI"
BASE COUNT         2437 a         1118 c         1539 g         1868 t
ORIGIN      
        1 gggtcgtatg agtgaactcg gatattccat gatgtttggg gaggtcgaaa aaaacttctt
       61 tatgaagcac atcaaaggtc gaggttatgt ggatacaggt ggcagtgtga ttagtgagtt
      121 ttatacgcca cttgtaccaa aagggtatga tttcttagat tcaattagta aattagaaaa
      181 gatgaatgat tgagtgatct tcaatactga ctttatactt caagtaacgt ataatacttt
      241 tatatagtag gaagaaaggg gataattaat atggaaagta atgattctta tttagagtat
      301 gcaaaagcaa ataaggataa gtttatttct tatattatca aagggaaatc ccccgaagtt
      361 ggacgagacg cagtttttat ggcagggagt cctggggctg gaaaatcaga ggttgccatt
      421 ggattagctg agaattatga taaccatgtg attattgatg cggattactt tcgcacccag
      481 tttcctgatt ataatggaaa aaactctagt ctctttcaaa aagcatcttc ttggttggta
      541 gagcaggcat ttagatatgt cttagatcat ggctattctt ttattctgga tgcaactttt
      601 gcaatattaa gtgctgaaaa aaatatctcg cgggcgttga aaaaacattt tcgagtgacg
      661 attttctatg tttatcaaga ccctaaaatc gcttggaaat ttacacaaga acgtgaaatt
      721 gcagagggac gtcatgtgcc gaaaaaggca tttattaacg cttttttcaa atcaagagag
      781 aacattgcaa aagtaaagag taaacatcca gatgtattgc ttcatatcat aataaaagat
      841 tatacgaata atatttccga agttcattat gctacggata atctagaatt atttttacca
      901 ctagggtata gtaggaaaga tttggaggtt caattacatg actgagaaag aacaagtaac
      961 gaaaattgta aagaaataca ataagagcat tgcggattta tcggaaaatg ctactgcaaa
     1021 agagttcaaa acggtgatta aatatgtagc cgatcaggcc aatgaaaaac aacggaaatt
     1081 agttggatta aataaaaaat agtaggacaa attaataatg tatgagccaa gagcaaaatg
     1141 ttcttggctt ttttctttgc aatgaatgag gtaatgtatg agatttttag atttattcgc
     1201 cggtattggt ggctttcgtt taggtatgga acaggcgagc catcattgta tcggtttttg
     1261 tgaaattgat aaatttgcta gacgtagtta taaagcaatt catgatacaa gtaaggaggt
     1321 ggaaatgcat gacatcacaa gtgtatcaga tgagtttatt caatccctcg gaccagtgga
     1381 catcctttgc ggcggatttc cgtgccaagc tttttcaatt gcgggaaagc ggcaaagatt
     1441 ttccgatact cgaggtactt tattctttga aatcgctcgg ttcaccactc ttctccgacc
     1501 taagctttta ttccttgaga acgtccgagg attgctcaat cacgaaggag gggctacgtt
     1561 cgagacgatc ctccgaacgc tggatggatt ggggtatgac gtggagtggt aggtgcttaa
     1621 ctcaaaggcc tacattcccc aaagccggga gcggatattc cttatcggac attctcgaga
     1681 cgcatgtacc gaacaagtat ttcctatcat tggaccgtct tcaacatctg atcaaaacat
     1741 cagaaatttg gtaaatatca atccttccaa tcgaggaatg ggtggacaag tctatggttc
     1801 agatggcgta gcgccaacct taacaggtga tgaaggaatc aaaatcgcac tgccagcaag
     1861 ggatggaatc tctgtagcag gactattacc gggaaagttt gaacaaggta atcgagttta
     1921 tgaagttact ggaaccgccc ccaccttgtc aacgaaacaa ggtggtacaa aaatcatgat
     1981 tcgaaaaaat gaaacagaat atcaagaggt gaagccagaa gacagtgtga atctggcttt
     2041 tcctaattcc acaagtcgcc gaggtcgtct gggaaaacag agtgttcata ccttactaac
     2101 aggagaccaa caagcgatcg tcacggatca gtatcaaatt cggaagctaa cacctagaga
     2161 gtgttggcga cttcagggct ttcccgattg ggcttttgat cgagattctc aagtcaattc
     2221 agatagtcag ttgtataagc aagccggaaa ctctgtaaca gttccggtca tttttgatat
     2281 tgccagaaga ttaaaagagt tggatgtaca tggtttatga tgagttgatt ggagaaattt
     2341 attgggtgat tggaaagatt cagtcagacc cagaattaga agaacaattg cgacggttaa
     2401 aatttgatat tcgcaagaat ggtgtcaaag tcgctggcga tccatattta atgaatgagg
     2461 agacggatgc tcgaattgaa ataaatcaag taattgcaga atttgagcgg attgcggacc
     2521 aagcaaaaga accagatatt cgtcaatact tgttagaaat gaaagcagag ttggaagtaa
     2581 atggtattac agatgagtaa cctaaaccaa cacaactgac tgttaggcgc tgaccgcgga
     2641 ggattcgcga agcagaaatc ctccgtggtg ctgtgcctgt tcatggacgg cgttagccga
     2701 ccatgatgtc tcacccccgt atctaacagg ggggtacaaa aacacaaaaa ataagtaagc
     2761 aaccattaag aatgcttgtt gtatcaaaga tagtaagtaa tttgtatagg tgttaactca
     2821 tttgaaaaag ttaacacctt gaatttggag gtgagaactt ggcacaacgg aatttagatt
     2881 atcggctatt aaaagaccga cgcaacgaat acggcgtttc acaaaataaa ttggctacgg
     2941 cttgtggact tagtcggccg tacttaaatc agatagaaaa tggtggcgta accgcatcta
     3001 taaaaaccat gaggaaaatt tttgaccaac tggaaagctt taatcccgat ttgcctttga
     3061 cgttactgtt tgactatgta aggattcgct ttcccacaac ggatgcacga aaaattattc
     3121 aagaaattct ccatttgaaa tttgagtata tgctccatga agattatgcc ttttactcct
     3181 atcaagaaca gtatgtcatg ggtgatattg tggtgatgtt gtctcatgaa gaagataaag
     3241 gtgtgctttt agaattaaag gggcgaggtt gccgacaatt tgaaactttt ttactcgctc
     3301 aaaagcgtag ctggtacgac tttttcgagg attgtctaaa ggccggtggc gtgatgaaac
     3361 gcttggactt ggcaatcaat gatcgagtgg ggctattgga tatacctgag ctaacgaaaa
     3421 aatgtcagaa ggaagaatgt atctccttgt ttcgtacctt taaaagttat cgttccgggg
     3481 aacttttaaa ggctgatgaa aaggacggca tgggcaatac cttatatatc ggcagtctca
     3541 agagtgaggt ttatttctgt ttgtatgaaa aagactatga acaatatatc aagttaggga
     3601 ttccattaga ccaaactgag acgaaaaatc gttttgagat tcgactgaaa aatgaccgtg
     3661 cttttcatgc gattcaagat ttgttaaaag gtcgtagcat tgagagcacc acgttttcca
     3721 ttatcaatcg ttacttgcga tttgcggata aagtagaagg taaaaggcga accaactggc
     3781 ccttgaatga acaatggggg cgttttattg gacggaatcg gaaagagatt caattaactt
     3841 ccgagccaaa accgtatacc attgaacgaa ccttgaattg gctaggccga caagtcgccc
     3901 ctacgtggaa aatggctaag gagttggatc gattgaatcg gacaacctat atccaggata
     3961 tggtacagaa tgcacgctta tcagaccgac ataaaaagat tttggagcaa caaagtatgg
     4021 caattgaaaa tttgattata tgaaaagagg aatcgtcatg ggaattgtaa aagatatttt
     4081 tttggtattt ggtggcagta tgcttggtgt tactgtgatg tgcttgatga atgcaagtgc
     4141 agcagcggat cgagcaatgg aaaagaaagg aaagtgacaa gatgaatttc ggacaaaatt
     4201 tatgtgcgac tcgttcctta gtgaaaagct aaggcactaa taaaagaacg aaaaagtttg
     4261 gttattagga gaactgataa tctgacaggt ggaatgatga agtaacgctc tgaaacgcct
     4321 gccctgagcc tccgacaagc attgtatgag gaaactcaga atgtttgaag ctcggtaaag
     4381 acggctgaaa gataccgtaa tagttgatga acatatatct tctatcgaaa actatccaga
     4441 ggtgggtagc gtatccaaca ggtcgggggt ctataaaata tctatggtta gaatgttcta
     4501 taaggaactg acgaaacagc gaatgtacgg gtctaaattt gaactttgta gaaatgcaaa
     4561 ggtacgagaa atcgtagctg gtgtggcaaa gtaagaatat aggttatgaa atgccatata
     4621 acgttacagg cggtatcaag ccagcaggct tatagctagt gacctaagga tatatatgta
     4681 tagataagat tatcggaacg aggaaaggta ttgggttctc atcaagagaa taaactgacg
     4741 aagaacaata agcagttgaa ctaatgctga aaagcagagg gcgaacctaa gaaattcttg
     4801 taatgagaat ggaggaatgc cctcaagtcg tgtatatatt agaaaagtat tatgttgttt
     4861 caataaggat tacgagtaag ataaaaaagc tcactcaatt tcaagtaaag gagtgaagcc
     4921 ttatgcctaa aaataaaaat gaaacattgt gtgtagaaga tttaagacac gctgaatatt
     4981 acgaaatgca aaacaccttt gatgatttat atgccaaaag taagaatgga gatattttca
     5041 ctcatcttat ggatattatc ctatcgagag aaaatatatt actggcatat cgaaatatca
     5101 aagcaaatgc aggcagtaaa acagcaggaa cagacggtac aataattaaa gatattggca
     5161 aattgccagc agaaacagtt gtcaaaaaag taagatacat tgttgcaggc agtccacatg
     5221 ggtatcgacc taagccagtg aggcgaaaag aaataccaaa accaaatggt aaaaccagac
     5281 ctctaggtat tccttgtatg tgggacaggc ttatacaaca atgtataaaa caagtattag
     5341 aaccaatctg cgaagctaaa tttagtgaaa acagctatgg ttttagacct aataggtcag
     5401 ttgaaaatgc aataaaagca acctataacc gcctacaaat cagccagcta cattatgtga
     5461 ttgaatttga tattaagggt ttctttgaca acgtgaacca ttccaagctg ataaaacaga
     5521 tatgggctat gggaatacgg gacaagcact tgatattcat tttaaaaagg atattaaaag
     5581 ctccaatcaa aatgactaac ggtacaataa catatccaga gaaaggaact ccgcaagggg
     5641 gaataatatc cccactacta gcaaacattg ttcttaatga gttagaccat tgggtagaaa
     5701 gccaatggca ggaaaatcct gttacaaaaa actatgtggt tcatatcaat aaaagcggta
     5761 gcccatgtaa aagcaacgct tacaaagaaa tgaagaaaac aaagttaaag gaaatgtata
     5821 tggttcgtta tgcagatgat tttagagttt tctgccgcta caaggaaagt gctgaaaaag
     5881 ccaaaatagc aatcactcaa tggattgaac aacgattaaa attggaagta tcacaagaaa
     5941 aaacaagaat tgtaaatgtt agaaaaagat actccgactt tcttggtttc aagattaaaa
     6001 tgataccgag aagaaagaag ttagttgtta aatcacatat aagtgataaa caattcaaaa
     6061 accaaaaaga caagctggta tcacaggcaa agaaaattgc ttctccctca aaagggaaaa
     6121 cggaattaga agaaacaaga ctttataatt caatggtatt aggtatgcaa aattattatc
     6181 agattgcaac gaatgtaaat ctggattgta tgaaactgaa tagagctgta atggctatct
     6241 tcactaacag attaggtaca aacaaaaggg gcagattgag aaaaacaggc agacaactta
     6301 cgacaaagga ggcaacaaga tatggtaaat ctaaaatgct tcggtatgtt gctggcgagg
     6361 gcgaacctat tttccctgtt ggatatatcc aacacagaaa accaatggca aaggtgtatt
     6421 tagcgaattg ctacactcta gagggaagaa aatttatcca caccaatcta agtgttgata
     6481 aattactgat gtaccagtta atgaaattat ctttggaaaa tcgcacaata gaatacgcag
     6541 acaatcgaat ttcgctattt tctgctcaac atggaaaatg tgctataact ctggaagaat
     6601 ttcaacaagc taatgaaata cattgtcatc atattgtacc aactggagct ggtggaaatg
     6661 acgattataa aaatcttatt ttggtaaaag aggcggtaca ccgtctaata cacgctaaaa
     6721 cagaagaaac aatacaaaaa tatatagctc tattgaagct aaataaagtc cagctcataa
     6781 gactaaataa atatagagta ttagctggca atcaagaatt aaacttgata taggtctact
     6841 acataaatac ttttcaatat aaacacgatg gaacgcggag tgcggtgaaa gtcgcacgct
     6901 ccgtgtgaat ggggggaaaa gtttgagata tttataatat caggaactta cctatccata
     6961 ta
//
LOCUS       DAFBVQ010000094         6901 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.099, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000094 DAFBVQ010000000
VERSION     DAFBVQ010000094.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6901)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6901)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6901
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.099"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            1..345
                     /locus_tag="LLC22_002601"
                     /pseudo
     CDS             1..345
                     /locus_tag="LLC22_002601"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="frameshifted; incomplete; missing N-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=3
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
     gene            361..510
                     /locus_tag="LLC22_002602"
     CDS             361..510
                     /locus_tag="LLC22_002602"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435815.1"
                     /translation="MRNTTHKQQEIENQKAKIRSEQEKMRASKRRLQQLKNQQRIQKE
                     IELDR"
     gene            591..1187
                     /locus_tag="LLC22_002603"
     CDS             591..1187
                     /locus_tag="LLC22_002603"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330586.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IV toxin-antitoxin system AbiEi family
                     antitoxin domain-containing protein"
                     /protein_id="HBK5435816.1"
                     /translation="MTKAMVYKLLEEFNGTLALKDAKKAGISPVTIKRMVDRGELDRE
                     YPGFFTLPGQFPDELFMAQKKYERGIISHITALDLYDLTDMIPRQIDLTVPYGYHVSE
                     KGLKEFAVELHYTKAEWYELGKIEIKSRYGNPIIAYDPEKTLCDIWNPWYNVEDEIKV
                     KAIKNYMESDRKNLRKLNEYRRILPTDKTMRSYIMALN"
     gene            1200..2099
                     /locus_tag="LLC22_002604"
     CDS             1200..2099
                     /locus_tag="LLC22_002604"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyl transferase AbiEii/AbiGii toxin
                     family protein"
                     /protein_id="HBK5435817.1"
                     /translation="MTPTQLKAKVKNISREKEVDPQLVLRHFMMEKFLEKISESPYRE
                     NFVLKGGFLIGSKYGIENRTTKDIDTTLREMKVTKETLTTVLNDIFSTPTKEGIQFEI
                     QGMKETREADYYPGFSLRVLAHLENMRPDFKVDVTTGDSIYPATITHSHKLMFEDRTI
                     PLESYPTEQIIAEKLSATFDFLTDNSRGKDFYDLYTIPKMEKIDEKTLKDSVRNTFTR
                     RGKTDPLKIYYEKDMDVLKNSHELKDTWKKYQKSNPYAASITYDETMDSISNLMEKVI
                     HVEEKERKLAYQRHQQMNREMER"
     gene            2102..2233
                     /gene="ssb"
                     /locus_tag="LLC22_002605"
     CDS             2102..2233
                     /gene="ssb"
                     /locus_tag="LLC22_002605"
                     /inference="COORDINATES: protein motif:HMM:TIGR00621.2"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5435818.1"
                     /translation="MINNVTLVGRLTKDPDLRYTASGTAVATFTLAVNRNFTNQNGN"
     gene            2255..2587
                     /gene="ssb"
                     /locus_tag="LLC22_002606"
     CDS             2255..2587
                     /gene="ssb"
                     /locus_tag="LLC22_002606"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305808.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5435819.1"
                     /translation="MIWRKPAETMATLAKKGSLIGVVGRIQTRTYDNQQGQRVYVTEV
                     VADNFQLLESKAATESRAHADQSSTSPSTATFEQRNTATPNNNGLNASQNPFGGQSID
                     ISDDDLPF"
     gene            2632..2865
                     /locus_tag="LLC22_002607"
     CDS             2632..2865
                     /locus_tag="LLC22_002607"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303482.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435820.1"
                     /translation="MDLLIPVIAFIDGISLGVTENPLVNRIAKGSLFLVFVYLVCSYL
                     LKRAGKDNSFWRLTKVTVAATAVILTAILPLYM"
     gene            complement(3024..3146)
                     /locus_tag="LLC22_002608"
     CDS             complement(3024..3146)
                     /locus_tag="LLC22_002608"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002389461.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="putative holin-like toxin"
                     /protein_id="HBK5435821.1"
                     /translation="MKGVSLLSAYETIQTILGFGMFTIALISLIVNMLKNDKKK"
     gene            3336..3560
                     /locus_tag="LLC22_002609"
     CDS             3336..3560
                     /locus_tag="LLC22_002609"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305809.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435822.1"
                     /translation="MIKTQPLLVRFTLRTSHEPINCVVANIEIADKLLILEEGKYTIS
                     VTGHFNKRKQLVIESMQIRNPDHFTRSMSI"
     gene            4003..4209
                     /locus_tag="LLC22_002610"
     CDS             4003..4209
                     /locus_tag="LLC22_002610"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853414.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA helicase UvrA"
                     /protein_id="HBK5435823.1"
                     /translation="MRKKFDYWGVPFSELFPNYHAPHTVECDCGERAKCIKSYCLYQC
                     PTCGKKYTLSYGDYILIDEKGKKR"
     gene            4209..4460
                     /locus_tag="LLC22_002611"
     CDS             4209..4460
                     /locus_tag="LLC22_002611"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314430.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435824.1"
                     /translation="MKTQHKLLTVKEVVQILVDKEVISEKVAEVLLIPRYWTIETPLV
                     EDAPTMLFEDLVKIAGYELHYQENLETYENEYWLTKLEN"
     gene            4476..4631
                     /locus_tag="LLC22_002612"
     CDS             4476..4631
                     /locus_tag="LLC22_002612"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300799.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435825.1"
                     /translation="MAQNYYDEFVKLPLDKMAQKMEDMTFLYNETRVPKKHYKEKLSV
                     AVEEMIE"
     gene            4641..4913
                     /locus_tag="LLC22_002613"
     CDS             4641..4913
                     /locus_tag="LLC22_002613"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435826.1"
                     /translation="MNLIATYYRTLEELKKQNAKWFFQALLCLEVGVKPSTIKPSEYQ
                     ALELTYAKFIETKKAKTVSSEWLDYFENINKYGAYYTMKKEDNENE"
     gene            5358..5537
                     /locus_tag="LLC22_002614"
     CDS             5358..5537
                     /locus_tag="LLC22_002614"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435827.1"
                     /translation="MPIAIGNKRLPVTLDEKRQKELQQLKQKYGKSESKIMCIALDLL
                     IAQEKAGFDVPALKK"
     gene            5596..5952
                     /locus_tag="LLC22_002615"
     CDS             5596..5952
                     /locus_tag="LLC22_002615"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002375958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435828.1"
                     /translation="MLKTKKNSYKLKLSILSIICLLGMIISGHLYRVAYTQFIEYKVH
                     SLGLAGDRYVEYVHYSLKCSSYILLWLIFSLFELLNLIAISSYHLDKLNTKSSRYNEV
                     FKENVKLESDLNKLKK"
BASE COUNT         2469 a         1114 c         1369 g         1949 t
ORIGIN      
        1 ccacttttct agccaatatc caaaaatttg tctctcactt attggaagtc gtaccagggc
       61 aaatccaatc cactgatttt ggatcgacgt tacaagaagt gaaagcagcc agtgaaaagc
      121 aagaagccgc gcgtcattta ggaatttgtc caaaatgcca ggaacaagaa gtcttactct
      181 atcaaaaggt ggcagcttgt acgtctgaag cctgtgattt taaaaggtca gaagggttca
      241 tttgaagcaa cgattgtttt aaaagaagac ttcactacag gctttgaatt ttctgaaaag
      301 aaaaaaacga acttcaagaa aagaacacgc cgcactgcaa aataatggag ggttaatctt
      361 atgcgtaata ccacacacaa acaacaagaa atcgaaaatc aaaaagccaa aattcgttca
      421 gaacaggaaa aaatgcgtgc cagcaaacga agactgcagc aattgaagaa ccagcagagg
      481 attcaaaaag aaatcgaatt agatcgataa aatcttccta actattgtat acgtataaac
      541 ttatgttata ctgtttttat aagtttatac gtatacaaag gagggagaaa atgacaaaag
      601 caatggtata caagctgcta gaagaattta atggaacttt ggctttgaag gatgccaaaa
      661 aagcgggcat ttctcctgta acgatcaaac gtatggtaga tcgaggggag ctggatcgag
      721 agtatccagg ttttttcacc ttacctggtc aatttcctga tgaattgttt atggcgcaaa
      781 aaaaatatga acgcggcatt atttcacata ttaccgcgtt agatttgtat gatttaacag
      841 atatgatccc tagacagatc gatctgactg taccttacgg ttatcacgtt tctgaaaaag
      901 gattgaagga attcgcagtt gagctacact atacaaaagc ggaatggtat gaattaggta
      961 agattgaaat aaaaagtcgc tatgggaatc ctattatagc ttatgatcca gaaaaaacct
     1021 tgtgtgacat ttggaatccc tggtataacg ttgaggatga aatcaaagta aaagcaatca
     1081 aaaactacat ggagtcggac agaaaaaatc ttagaaaatt gaatgagtat cgacgaattt
     1141 tgcctacaga taaaacgatg cgctcttata ttatggcttt aaattaaagg agaatacaca
     1201 tgacacctac gcaattaaaa gcaaaagtga agaatatttc tagagaaaaa gaagttgatc
     1261 cgcagcttgt tttaagacat tttatgatgg aaaaattctt ggaaaaaatc tcagagtctc
     1321 cttatcgtga aaattttgtg ttaaaaggcg gcttcttaat tggctcaaag tatggcattg
     1381 aaaatcgaac aactaaagac attgatacga ctttacggga aatgaaagta accaaagaaa
     1441 cattgacaac ggttctaaac gatatttttt caacgccgac gaaagaaggc attcaatttg
     1501 agattcaagg aatgaaagaa acgagggaag ctgattatta tccagggttt agcttacgtg
     1561 tactggcaca tttggaaaac atgcggccag attttaaggt agatgttact acaggtgact
     1621 cgatctatcc tgcgacgatc actcacagtc ataaattgat gtttgaggat cgaacgattc
     1681 ctttggaatc ctatcctaca gaacaaatta ttgctgaaaa attaagtgca acctttgatt
     1741 ttttaacaga taattcgaga ggaaaagatt tttatgatct ctatactatt cctaaaatgg
     1801 agaagatcga tgagaagacc ttgaaagata gtgtgagaaa tacatttaca cgtcgaggaa
     1861 aaactgatcc gttaaagata tactatgaaa aggatatgga tgtactgaaa aatagtcacg
     1921 agctaaaaga tacctggaag aaatatcaaa aaagcaatcc ttatgctgcg tcgatcacgt
     1981 acgatgagac aatggattcg attagtaatt tgatggaaaa agtgattcac gtcgaagaaa
     2041 aagagcgaaa actagcttat caaagacacc aacagatgaa tagagaaatg gagagataaa
     2101 gatgattaat aatgtgacat tagtaggacg cttaaccaaa gatcctgatt tacgttatac
     2161 cgcaagtggt actgcagtag cgacttttac cctagccgtc aaccgaaatt tcacgaatca
     2221 aaacggcaat tgagaagccg attttattaa ctgcgtgatt tggcgcaaac cagcagaaac
     2281 aatggcgaca ttagctaaaa aaggtagctt gattggtgta gttgggcgga ttcaaacgcg
     2341 gacttacgac aaccagcaag gacaacgtgt atatgtgact gaagttgtag cagataactt
     2401 tcaactatta gaaagtaaag cagcgacaga gagccgtgcg cacgctgatc aatcgtccac
     2461 cagtccaagc accgccacct ttgaacaacg gaatacagcg acgcctaaca acaatggatt
     2521 gaacgcttca cagaatccat ttggtggaca atcaatcgat attagcgatg atgatctacc
     2581 gttttagttt gagaaagaag gagtaagcat ggcaaaaaaa ttagtctgac gatggatcta
     2641 ttgatacccg taattgcatt tatagacggg atttctttgg gcgtcactga aaatcctttg
     2701 gtaaatagaa ttgcgaaagg atcactattt cttgtattcg tgtatcttgt ctgttcttat
     2761 cttttaaaaa gagcaggaaa ggataattcc ttttggcgat tgactaaagt cacagtagca
     2821 gcgacagctg ttatacttac ggctattcta ccgctttata tgtagagtta acgggaaatc
     2881 gttgaacttc ttgcgaaata ttgctataat gaacatgaaa aagaggagtt gcgctaacaa
     2941 cccctcatta acagcaccga ttaaagaacg gtggcagaat attagttatt tggaaataac
     3001 cgctgacctg ctaaagtaga cggttatttc tttttgtcat ttttaagcat atttacaatc
     3061 aaactaatca aagcaatggt aaacatacca aaaccaagaa tggtttgaat tgtctcatat
     3121 gcggacaaaa ggcttactcc tttcatagat tttagcactt acattcataa gcaccaccac
     3181 ctttccagaa gtcgccaccg tcttcaaact ttactgtctt gactattata gcatatctaa
     3241 aatcgaataa aaattctcaa ttttagctgt ttttgctata attttagcga ggtgatcgtg
     3301 atggaacaat atattggttt actcgataaa ttagggtgat caagacacag ccattgcttg
     3361 tgcgatttac attacgcacg agtcatgaac caatcaattg tgtagtggcc aatatagaaa
     3421 tagcggataa attgctgatt ttggaagaag gcaagtatac tatttcagtg acaggtcact
     3481 tcaataaacg aaagcaacta gtcattgaat caatgcaaat tagaaaccct gatcatttta
     3541 cgcgatcgat gagcatataa aagaagagct gcagtcctaa atgaggattg tagctctttt
     3601 tgttttacat agaaacagta aaaatgaaaa ggcctgttta ggaaggcaca agcgccttct
     3661 caattgaaag acctttctct cactccaacc gccaccgccg ttcgagaaga aaggaagtga
     3721 acgctacgcg ttcactaaga taaagggtct tgcatagcaa gacaaaatag aaaaaatttc
     3781 ctctcaccaa aaggttcgct cctgttcgtt atctctttat tgatttgtca gaccggcaac
     3841 aagttgcctt ttatcaccaa aaagcgacaa ggacaagggt aaatggcacg ctgcgcgccc
     3901 ttgtcttgtc gcttttcgtt gattcattct ggccaacaaa tcaataaaga aagaactaac
     3961 gaaaggaagt aaaacctttc ctaagaggag gcagaatcaa tcatgcgaaa gaaatttgat
     4021 tattggggtg ttcccttcag cgaattattc ccaaactatc atgcaccaca tactgtcgaa
     4081 tgcgattgtg gagaaagagc gaaatgtatc aaaagctatt gtttgtatca atgtccaaca
     4141 tgcgggaaaa aatatacctt gtcttatggc gattatattt taattgatga gaaaggaaag
     4201 aaacgctgat gaaaacacaa cacaaattat tgactgtaaa agaagtcgtt caaattttgg
     4261 tggacaaaga agtcatttct gaaaaagtag cagaagtttt acttattccg cggtactgga
     4321 cgatagaaac ccctttagta gaggatgcac cgactatgct atttgaagac ctagtgaaga
     4381 ttgcaggata tgaactgcat tatcaagaaa acttggaaac ttatgaaaac gaatattggt
     4441 taaccaaatt agagaactaa aaaggagaaa aaaatatggc tcaaaattac tatgacgaat
     4501 ttgtcaaatt acctttggat aaaatggcac aaaaaatgga ggatatgacg ttcctataca
     4561 acgaaacacg tgttccaaaa aaacattata aagaaaaatt gtcggtagct gtggaagaaa
     4621 tgattgaata aggtgtcgaa atgaatctta ttgcgacgta ctatcgaaca ctggaagaac
     4681 tgaaaaagca aaatgcaaaa tggtttttcc aagccttact atgcttggaa gtaggtgtca
     4741 aaccaagcac tattaaacct tctgaatacc aagctttaga actaacgtat gcgaaattta
     4801 tcgaaacgaa aaaagccaag actgtttcaa gtgaatggtt agattatttt gaaaatatca
     4861 ataagtatgg cgcatattac accatgaaaa aggaagacaa cgaaaatgaa taaggtgatt
     4921 tatcaactaa caacggattc catatcaacg atttgaaaga aaaaaaggtc aataatcatt
     4981 tataccgaaa agtgagaatg tgtgaaacaa ggacaaaaaa agcctagtaa ctaaggaaat
     5041 ggttcttatt tcgcaccaat cgctccaacc gcccccgccg cttaggtggt gcgaaataaa
     5101 cgggcaaagc ccgataactt aagagaaaga aggtgatcca tttgaacaag attattccct
     5161 tattgttagt actgtttgtt ggcgaaatac ttatgcgaga tagtgcagct gtacagttaa
     5221 acctcgctgt atttttggta atactggtgt tttgtttgat cttttggcgg tttgtattag
     5281 tcctcgtgag tctactattc aagatgattg cagccatatt tttcataggg ttatttcgat
     5341 gaaaggagtg agtaccaatg ccaattgcaa taggaaataa acggttaccc gtgacattag
     5401 atgaaaagag acaaaaagaa ttgcagcaac taaagcagaa gtatggcaaa agtgaatcta
     5461 agattatgtg tattgcgtta gatctattga tcgcgcaaga aaaagcagga tttgatgtac
     5521 cagcgctaaa aaagtgacgt cactttttaa tttgatctat ataagtgata tcacttttac
     5581 caaggaggga attaaatgtt aaaaactaaa aagaattcgt acaaattaaa gcttagtata
     5641 ctatctatta tttgtctttt aggcatgata attagtggtc atttgtatag agtggcatat
     5701 acgcagttta ttgagtacaa ggttcactct ttaggattag ctggggatcg atacgttgaa
     5761 tatgtccatt attcattaaa atgttcttca tatattcttc tttggcttat tttttcattg
     5821 tttgaattgc taaatttaat agcaatatct tcatatcact tagataagct aaataccaaa
     5881 tctagccgtt ataacgaagt gtttaaggaa aatgtgaagt tagaaagtga cttaaacaag
     5941 ctaaaaaaat aaaaagaaga aaacataagt taactaaaat tattttatta agaatgatgg
     6001 aatataagga taaggttacc aacataacga tcattacttc tctgatatgc tatggacttc
     6061 tatcaatcag tattttgtct atagattatg gagtaactat actgcaagcc ttagttttgg
     6121 ctatgcctat gtatctatct ttgtttatca tgcatgaaat atataagcta tttgttttat
     6181 caaaaaatgt agaaatacgg gtaaatattt tggtgaatag ttatcaaaaa gaactcaaag
     6241 aaagaagacg gtggcggtat ttattgaaag gatgaaaaag taggatttga catactggta
     6301 ttcagaaagt gccgtcactt ttaaaacaat ggaaaaggtg gagataagat gaagaaaaaa
     6361 caaactaaac tatcattagc agatatttaa cacagttaac cgcaactgaa gatggtgttg
     6421 ttgaatttga acaatctgaa attgcggtag tagatgatcg ttaccttaaa atgccttact
     6481 tctttgacca agcaaaggtc atttgccttt gtcactacga tggggtacgt gattttaggc
     6541 gttaaaaagt agtgattata tcaactttac gagtaaatat aaatttagac atgaaactga
     6601 attatccaat ggaaaatcat ggtttataat ctagaaaaat tatagtaatg attggattat
     6661 atatattctt tcgtattttc gtacaactgt agcttgtcaa aattgagaaa tttaaccgat
     6721 taggtacttt acatcgttat ttgggtaatt tctaaaacat gaagcttacc aacgaataaa
     6781 ctgagactat cttattaatt gatcaatata agaaaatatc tttgaggaga tgatgtacta
     6841 tgttttcgtc tatccacgat tggttaggtg gtcttttcgg cggtggaggt aaaggttttt
     6901 a
//
LOCUS       DAFBVQ010000095         6644 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.100, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000095 DAFBVQ010000000
VERSION     DAFBVQ010000095.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6644)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6644)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6644
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.100"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(1..859)
                     /locus_tag="LLC22_002616"
                     /pseudo
     CDS             complement(1..859)
                     /locus_tag="LLC22_002616"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
     gene            1102..1557
                     /gene="tnpA"
                     /locus_tag="LLC22_002617"
     CDS             1102..1557
                     /gene="tnpA"
                     /locus_tag="LLC22_002617"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605 family transposase"
                     /protein_id="HBK5435829.1"
                     /translation="MSNDDKSLAYTRWNCKYHIIFTPKYQRKVIYGQLRKDLGKILRK
                     LCEMKDVEIIEAHAMLDHIHMLVRVPPKICISSFMGYLKGRSAVLIHEQHANLKYKYG
                     NKSFWSKRYYVSTVGLNQKTNEKYIREQEADDRIRYIISKREYVEPFKK"
     gene            1822..1920
                     /locus_tag="LLC22_002618"
                     /pseudo
     CDS             1822..1920
                     /locus_tag="LLC22_002618"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
     gene            complement(2143..2373)
                     /locus_tag="LLC22_002619"
     CDS             complement(2143..2373)
                     /locus_tag="LLC22_002619"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631988.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="resolvase"
                     /protein_id="HBK5435830.1"
                     /translation="MDEAMDHPLLNKFIKDLILQIFSMIDEQEPTESKRHRAQGIIKI
                     AKRMFSIKGVLSYTVLIQKIPNHLVYKNNVED"
     gene            complement(2603..3421)
                     /locus_tag="LLC22_002620"
     CDS             complement(2603..3421)
                     /locus_tag="LLC22_002620"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002313161.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MurR/RpiR family transcriptional regulator"
                     /protein_id="HBK5435831.1"
                     /translation="MSYIYLIKENYPFLTKSEKKVADFILNSGKTIIYSTMSDIKKNT
                     KVGDATIIRFCQKIGFSGFSDLKIEIAKEDFSQKKEHPTSVKYYDEIANSLTEALYST
                     IRLLDEEKLNEAIKMITQSKNIYIFGVGSSGNTSLDLENMFLRVGVQAKAVLDPHFQA
                     QVASLLTVNDLVIIFSLSGKTKDTYDSLKIAKKNGAKIIAITNYIHSPIGKSADLVLQ
                     TAIEEFLNGGSLAGKISQLYICDLLVHGYEQNNNIDSVELREKVLRSIIDKSIE"
     gene            3582..4271
                     /locus_tag="LLC22_002621"
     CDS             3582..4271
                     /locus_tag="LLC22_002621"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002358533.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmannosamine-6-phosphate 2-epimerase"
                     /protein_id="HBK5435832.1"
                     /translation="MDKKRFLDLISKGLIVSCQALPGEPFYKEEESLMPYFALAAQRA
                     GAVGIRANSVRDIIEIRKCVSLPMIGIIKRDYPPESPFITATMREVDELVETGVEVIA
                     LDCTLRNRHDGLSINSFITKIKEKYPHQLFMADISTFEEGKNAYKAGIDFVGTTLSGY
                     TEESKKQDGPDIDLIKKLVEEGICVIAEGRIHTPEQAKEIKKIGVAGIVVGGAITRPQ
                     EIASRFVKALS"
     gene            4285..5787
                     /locus_tag="LLC22_002622"
     CDS             4285..5787
                     /locus_tag="LLC22_002622"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002367389.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5435833.1"
                     /translation="MFKKFSQLGRAFMLPIAILPVAGLLLGLGGALTNESAINAYPFL
                     DQPWLHTILSIMSYAGNAVFANLALIFAIGIAVGLANGDKGTAGLAGGVAYLVYTATI
                     SGFLELFSAKDATLDTGVVGSIVVGGTVAFLHNRYRKIELPQFLGFFGGSRFIPIVSS
                     LAAIIIGSFFYLIWPPIQNGLVVAGEQIAQMGSLGTFLYGFLLRLTGAVGLHHTIYPL
                     FWYTSLGGTETVAGSTIAGAQNIFFAQLADPNHTGLFTYGTRFFAGRFATMMFGLPAA
                     CYAMYRAIPKKNRKKNGGLYFSGALTSFLTGITEPVEYMFLFVAPWLYVIHAFLDGLS
                     FYFADILNIRVGNSFSGGLIDFLLFGVLQGNDKTNWLKLIPFGIAWAFIYFFVFTFFI
                     KKFKVAIPGMEEESEVHSEKVINKNTSLHEESLIIIEALGGKENIESVEACATRLRVA
                     VTNGEIIQKQTIKDTGATAVFEVKGGIQAVFGGKADLLSQEINQILGKDN"
     gene            5800..6276
                     /locus_tag="LLC22_002623"
     CDS             5800..6276
                     /locus_tag="LLC22_002623"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300328.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5435834.1"
                     /translation="MFEIFKKKKQETFYAPCSGKIISITEVNDPVFSQKLLGDGFAVI
                     PDGSKIYAPLAGRVTNIFPTKHAINIKSNSGIDYLIHIGIDTVELQGEPFSICVQEND
                     EVTPETSLVDVDFDKIIKSGKDTSVIVVFPEKNQFNDLIIDNGRIAHGNSCGKITF"
     gene            complement(6373..6483)
                     /locus_tag="LLC22_002624"
                     /pseudo
     CDS             complement(6373..6483)
                     /locus_tag="LLC22_002624"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         2172 a         1032 c         1204 g         2236 t
ORIGIN      
        1 acttgtcctc gataagaatt gtagcgccgt gatttacgtg tgtatgtcgt tacttttatt
       61 cctagcttct tgatcaggcg ctgaactttc tttttattga tagagaaacc gcggtttctt
      121 agttcattgg tcatccgtaa acagccataa tccttgtgct tctcccgaac tttaagcatt
      181 tccgcttcaa tctcttgatc tggattttta cggtccaatc gtttttgcca gtacataaag
      241 attgccttag ggaactttaa agtttctaga agctcaacta atttaaacgg tcctcggagg
      301 cttgcgatga ttcgtgcgat tgcttcattc gtcgttgttg ggcttcctgt tttcgcagct
      361 tcctcaattc ttttaaaaag gcattttcaa tttgaaggga acggactcgt ttctccaact
      421 cctcgatgcg ttcacgttct ttagacgttg ctttagttgt agattttttc ttatttttgg
      481 gttcattttt cttagacaag ataggtggac atcctttcgt ttttgagagt ccatcgatcc
      541 caccctcacg gaattgacgc atccaactag cgatcaaatt agggttgttc atgttaagtg
      601 tgttggcaac ttcacgatag gacagctcac ttgttagata taactctatc gcatccagct
      661 taaattgaac agaatatttt ttcttttgtc gctttcttac tagaccctct tcaccaaatt
      721 cttgataggc attgatccag cgcttcactt gtgatggagc cttaatggaa tatttctttg
      781 ccagataatc acttccgcct ttaccatcca agtaatcatg aacgatcttt aatttaagtt
      841 caaaagtata cttagccata aaaaataccg acctccaaaa gttagatttt ttggtctaac
      901 ttttgggggt cggtacaaaa cttaaaagtt ttagaccctt ttattttctt aatgacttca
      961 gtcagttttg tgcgtaaagc gtgcgaaaca agaaaaccgc gcgtttctac gcgtggaaga
     1021 agtatcttta gcgataaaaa ctcctttcga tatactagtg agtggctacc aaccgctcat
     1081 cagatcgaaa ggagtttttt catgtcaaat gacgataaaa gtttagcata tactcgttgg
     1141 aattgtaagt atcatattat ttttacacca aaatatcaac gaaaagtaat ctatgggcaa
     1201 ttacgaaaag atcttggaaa aatacttagg aagttgtgcg aaatgaaaga tgtggaaatc
     1261 atagaagcac atgcaatgct agatcatatt cacatgcttg ttcgagtacc accaaaaata
     1321 tgtatatcca gttttatggg gtatctgaaa ggtcgtagtg cggtactaat ccacgagcag
     1381 cacgcaaatc tcaaatataa atacggaaac aaatcctttt ggtcgaagag atactatgtg
     1441 agtacagtcg gattgaatca aaagacaaat gaaaaataca tccgtgaaca agaagctgat
     1501 gatcgcattc gatatattat aagtaaaaga gagtacgtag aaccatttaa aaaataaaga
     1561 gaagtaagtg agtgaagatg agcagttggc ggtcttttaa aaatcccctt ttaaggggca
     1621 gcgagtgtcg accccttcta gggggattaa aaatacaccc gtcctcacgg gtgtatgggt
     1681 tactgataga cttgatttta actggtgtca gaaacttatg tccagaaagg gtgatgaaat
     1741 tttggcaatt tacggctatt caagaattag cacaagcaac caagattaca aaacacaaat
     1801 tcaaacatta gaaaatgctg gcgcagaaat aatcttccta gaaaatcact ggattatcga
     1861 acacctttgg aagtattttt gagttacgta agtattgatg atctgtctaa cttaatttga
     1921 caattaagag tatatttact tcagatggta aggcaacaaa ataaaataca ataggcagat
     1981 gaactaataa ataaaatctg tattaaatac agataaatta atataaaaat caaaaggatc
     2041 ataaactttt aacaagtgat gaaatgggtg gaaattgatt cttatagaca gtttgtctca
     2101 taacattgaa gtattttgca attttagcat tgaaacactt ttttaatctt caacgttgtt
     2161 cttataaaca agatgattgg gaatcttttg aattaacact gtatagctta gaacaccctt
     2221 tatagaaaac attcgcttag caatcttaat aattccttgt gcccgatgtc gtttagattc
     2281 agtaggttcc tgctcatcga tcatggaaaa aatttgaagg atcagatcct taataaattt
     2341 atttaagaga ggatgatcca ttgcttcatc catactcgat aaactagtga taatgagcta
     2401 cacgtttttc tttcaagttg atcaatagct tccacgataa aaatatcttt agataaaatc
     2461 aagaaccgta ggaactacag ggatatttgg tcaataagag ccaccgctat tagtaaaaaa
     2521 taagctatca agtatgctct catcccaaga attgcctact tcaatcgtta aaaaccgtta
     2581 ggtttagcta agtgggggta gttcactcaa tacttttatc aataatagag cgcaaaactt
     2641 tttctcttaa ttcaactgaa tcaatattat tgttttgttc ataaccatga actaatagat
     2701 cacaaatata aagttgtgat atttttccag ctaaagatcc accattaaga aattcttcaa
     2761 tggctgtttg taaaactaag tctgcagact ttcctatagg tgaatgaata tagttagtta
     2821 tagcaataat ttttgcgcca ttttttttag ctattttcaa tgaatcataa gtatctttcg
     2881 ttttcccaga taaagaaaaa atgattacta aatcattaac tgttaataaa gaagcgactt
     2941 gggcttgaaa atgagggtct agtacagctt ttgcttgaac tcctacgcga agaaacatat
     3001 tttctaaatc aagactagta tttccactag atcccactcc aaatatatat atgttttttg
     3061 attgagtgat cattttaatg gcttcattca atttttcttc gtctaaaagc ctaatagtgg
     3121 aatagagagc ttctgttaaa ctattagcaa tttcatcata gtactttaca ctagtcggat
     3181 gttctttttt ttgactaaag tcttcctttg caatttcaat ttttaaatca gaaaaaccag
     3241 aaaaaccaat tttttgacaa aagcgaataa tagtagcatc gccaactttt gtgtttttct
     3301 taatatcact catcgtacta taaataatag ttttcccaga atttaaaata aaatcagcga
     3361 cttttttttc agacttcgtt aaaaatggat aattttcttt aattaaatag atataactca
     3421 tacaaactcc tctacaattt caacttttct ccattatact ccaaaataat aaaaaaaact
     3481 cctaaatact ccatttttat ctttactttt atgaaagcgg atgctatatt gtttttggag
     3541 ttgttatcca aaaataataa aaaattggag tgtttaggat aatggataaa aagaggtttt
     3601 tagatcttat ttcaaaaggt ttgattgttt cctgtcaagc attacctggt gaaccatttt
     3661 acaaagagga agaaagttta atgccttatt ttgctttggc tgctcaaagg gctggagcag
     3721 ttggtatacg tgcaaattct gttcgagata ttattgaaat tagaaagtgt gtatcattac
     3781 caatgattgg aattattaaa agagattatc caccagaatc tccattcatt actgccacta
     3841 tgagagaagt agatgaatta gtagaaaccg gtgttgaggt aatcgctctt gattgcactc
     3901 ttagaaatcg acatgatgga ctatctataa attcttttat tactaaaata aaagaaaaat
     3961 atcctcatca gttatttatg gcagatattt ctacatttga agaaggcaaa aatgcatata
     4021 aagcaggaat agattttgta ggaactactt taagtggata tactgaggaa agtaaaaaac
     4081 aagatgggcc agatatagat ttgattaaaa aattggtaga agaagggatt tgtgtaattg
     4141 ctgagggaag gattcatact ccagaacaag caaaagagat aaaaaaaata ggagttgcag
     4201 gtattgttgt gggtggtgct attactcgac cacaggaaat tgcatcaaga tttgttaaag
     4261 cattaagtta gggggagaaa taaaatgttt aaaaaatttt cacaattagg acgcgctttc
     4321 atgttaccaa ttgctatatt accagtagcc ggattactat tgggactggg aggagcgtta
     4381 acaaatgaga gtgctataaa tgcttatcca tttttagatc aaccgtggtt gcatacaatt
     4441 ttaagtatta tgagttatgc tggaaatgca gtttttgcaa acctagcact aatttttgca
     4501 attggtattg ctgtaggact tgcaaatgga gataaaggaa cagctggttt agctggtgga
     4561 gtagcttatc tagtatatac tgcaactatt agtgggtttc ttgaactttt ttcagcaaaa
     4621 gatgcaacac tagatacagg tgtagtggga tcaattgttg ttggtggtac tgttgcattt
     4681 ttacacaatc gttatagaaa aattgaatta ccacaattct taggtttttt tggaggatca
     4741 agatttattc cgattgtttc tagtttagct gcaatcatta ttggttcttt cttttattta
     4801 atttggccac caattcaaaa tggtttagta gttgctggtg aacaaattgc ccaaatgggt
     4861 agtttaggaa cttttttata tggtttttta ttgcgtttaa caggtgctgt tggactacac
     4921 cacaccattt accctttgtt ctggtataca tctttaggtg gtaccgaaac tgtagctgga
     4981 tcaacaattg ctggagccca aaatattttc tttgcccaac tagctgatcc aaaccacact
     5041 ggtctgttta cttatggtac tagatttttt gcaggaagat ttgcaacaat gatgtttgga
     5101 ttaccagcag catgttatgc aatgtatcgt gcaattccta agaaaaatcg taaaaagaat
     5161 ggtgggcttt attttagcgg ggcccttaca tcatttttaa ctggaattac tgaaccagtt
     5221 gaatatatgt ttttatttgt tgctccttgg ctttatgtga ttcatgcatt cttagatgga
     5281 ttatcttttt attttgctga tatcttaaat attcgtgtag ggaattcctt ttcaggtggt
     5341 ttgatcgact ttttattatt cggtgtactt caagggaatg acaaaactaa ttggttaaaa
     5401 ttaattcctt ttggtattgc atgggcattt atatatttct ttgtttttac attctttatc
     5461 aaaaaattta aggtagctat tcctggaatg gaagaagaat cagaagttca ttctgaaaaa
     5521 gtaataaaca aaaatacatc attacatgaa gagtctctta tcattattga agctcttggt
     5581 ggaaaagaaa atattgagtc tgttgaagct tgtgcaactc gtttgcgtgt tgctgttacg
     5641 aatggggaga ttattcaaaa acaaacaata aaagacactg gtgcaactgc tgtcttcgaa
     5701 gtgaagggtg gcatccaagc tgtttttgga gggaaagctg acttattaag tcaagaaatc
     5761 aatcaaatat taggaaaaga taattaggag gtttttaata tgtttgaaat tttcaaaaag
     5821 aaaaaacaag aaacttttta tgcaccttgt tccggaaaaa tcatttccat cacagaagta
     5881 aatgatcctg tcttttcaca aaaattacta ggtgatggtt ttgccgtcat acctgatggt
     5941 tcaaaaattt atgctccatt ggctggtcga gtaacaaata tatttcctac taaacatgct
     6001 attaatataa aaagcaactc aggcattgat tatttgattc atattggaat tgatacagtt
     6061 gaattacaag gagagccttt ttcgatttgt gttcaagaaa atgatgaggt tactcctgaa
     6121 acctcgttgg ttgatgtgga ttttgacaaa ataataaaat ctggtaaaga tacttctgtt
     6181 atagttgttt ttccggagaa aaatcagttc aatgatttaa taatagataa tggtcgaatt
     6241 gctcatggga attcatgtgg aaaaatcact ttttaaaaaa gtgtatataa aaagctataa
     6301 aataagctaa ataggatatt tgtcaaatga agttggtgaa cagaaagaac tgttttcttt
     6361 ctgttcattt ttttatttta ttagtaatga ttccccatgc caaatcatga tccgtaattt
     6421 aaagttataa aagcttcgaa atccattggc atttcgttgg aataccttga tatgattatt
     6481 caaatataaa atatagagag aagagagaga gggaagatat ttataaaggg caaagttatg
     6541 tttactcaac ttaggaaata gaaatagatc aatttatatt ctcttgtcaa tcgaatatga
     6601 accttagcac tatataccaa atatagtaaa atgctgaaag atgt
//
LOCUS       DAFBVQ010000096         6462 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.101, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000096 DAFBVQ010000000
VERSION     DAFBVQ010000096.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.101"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(109..564)
                     /locus_tag="LLC22_002625"
     CDS             complement(109..564)
                     /locus_tag="LLC22_002625"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290187.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435835.1"
                     /translation="MSKEMTALKFYFRNGETWTINRRHIGDLWIKQITTSFGRINGSE
                     FVEIHPCAGFKIEIFHEGDAVATHDINLGGLEMGMFNRALKYEDIERMEILYRNGTPD
                     LVYFPYLDKGTEGLDNQYQSTKISEKTGNLYIVINPDQRVEDVYGEFFE"
     gene            complement(718..1926)
                     /locus_tag="LLC22_002626"
     CDS             complement(718..1926)
                     /locus_tag="LLC22_002626"
                     /EC_number="2.7.7.72"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344136.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CCA tRNA nucleotidyltransferase"
                     /protein_id="HBK5435836.1"
                     /translation="MKLKQLPLEYQKAIPVLKKLENAGYEAYFVGGSVRDILLNQPIH
                     DVDIATSAFPEEIKQLFPKTIDIGIEHGTVLVLENDEQYEITTFRTESTYQDYRRPDH
                     VEFVRSLAEDLKRRDFTINAFALKEDGEIIDLFDGLQDLEEQILRAVGNPHERFHEDA
                     LRMMRGLRFVSQLGFKLEEETFYAIKENHELLGKISVERINVEFIKMLLGNERAAGIH
                     AFIETECYICCPGLKEEGEALLRFAELPSVPLKEESQAWALLISQLDLKENEIRSFLK
                     SWKCSNQMIQDVQALVQGLRQRETGALEPFELYFLGKKHALQVEELMIYFDETPQMDA
                     VGESYDRLPIKSLSELAVDGKILLEETGKKPGKWVSEALQLAEKAVVEQRIKNDKKQV
                     LDFLSKEKLI"
     gene            complement(2038..2370)
                     /locus_tag="LLC22_002627"
     CDS             complement(2038..2370)
                     /locus_tag="LLC22_002627"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002290045.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotide pyrophosphohydrolase"
                     /protein_id="HBK5435837.1"
                     /translation="MDKKRSLYSMQQEVDEYIQQFKVGYFSPLAQMARLTEEVGELAR
                     EVNHTYGEKSKKASEPVNSVAEELGDVLFVTMIMANSLNIDLTEVFEKNMEKFNQRDH
                     NRFERKDE"
     gene            2518..3393
                     /locus_tag="LLC22_002628"
     CDS             2518..3393
                     /locus_tag="LLC22_002628"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343259.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YitT family protein"
                     /protein_id="HBK5435838.1"
                     /translation="MVKRKTVKEVLFIIIGTSIYAFGLVYLNIANHLAEGGVSGITLI
                     LRALFGIDPAYTTLLINIPLILLGGKILGKRSLAYTVLGTLSLSFFLWIWQRVPLEIN
                     LQHDLLIVSLLAGLVAGVGSGIVYRMGGTTGGSDIIARILEQNYGITMGRSLLAFDII
                     VLLASLTYIDLKRMMYTLIVSYVFSRVIDSILDGGYSAKGLLVVSNKSEEIAPLLMTG
                     LQRGVTFLSGEGAFSGNSKKIIYMVVSSSELTEAKRIVHEIDEKAFLSIINVHEVEGQ
                     GFTYLKPQTRLLKKL"
     gene            complement(3475..4056)
                     /locus_tag="LLC22_002629"
     CDS             complement(3475..4056)
                     /locus_tag="LLC22_002629"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289878.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YpiB family protein"
                     /protein_id="HBK5435839.1"
                     /translation="MLIDVREKKNFLTWMVNHVSFSRREVFWILNYLANHEAILSNVH
                     FVEGANFADRGLQISDLSVEGEPMKLFLQGKEFTDTDQIFHEIRLNWKKPLYVECIFE
                     NAWQTREYLSILEDNPFSSWDSSVSEEDTELIERYFQEKEEEAKLKMLYAQIDQALED
                     GDRDAFLKLSDEVNRKILLQTQKKSNRVSEHNN"
     gene            complement(4062..5321)
                     /locus_tag="LLC22_002630"
     CDS             complement(4062..5321)
                     /locus_tag="LLC22_002630"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289879.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetratricopeptide repeat protein"
                     /protein_id="HBK5435840.1"
                     /translation="MNTNSEKMLQALSDEDLSQAQIFLEKALKEDPADILAELGEELL
                     AIGFLIEAKQIFEQLINQYPENDGLNIPLAEIAIEDNEIDLAFEYLEKVDKQSDYYPQ
                     SLLAIADLYQVIGIPEVSEAKLKEAAGLLPDEPLIQFALAELYFSVDRFKEAAVVYET
                     LLASGINEISGISMQERLGQSLSMQGEFEAAIVPLEEALKEERTDDRLFQLAFTNLQL
                     KENQQAINYLEELREVNPHYQSLYLYLGQALQEEEMIEEAQTVLEEGIKENPYQVELY
                     HLASENAFRLHDRQRAEELLLKALEVGDKQDETLLTLSNLYLDDERYEDVIQVINQME
                     ETANPYAEWNLAHAYNELEDFTVAAVHYEQAYHELSHEPDFLKEYAFFLREEGQLKRA
                     QELLTYYLTLEPGDMEALSLLDDLTER"
     gene            complement(5323..6369)
                     /locus_tag="LLC22_002631"
     CDS             complement(5323..6369)
                     /locus_tag="LLC22_002631"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298135.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435841.1"
                     /translation="MELDYQVEDALTKVFYGETLVSQLRELSIDQPILFLTNQRYYDL
                     FADKINPLFANQANNDWYICANTQCNHLTELKNLLDFVKRYPENQSMFIIGFGNEGIM
                     DLAGFFQKHTTLDSSLWMIPVSIRSLSRALTPQRTILQLPNRVVLQTINLPERIVYDQ
                     TISERQVDGKQIDFLTFICCGMICDHRFLQNLYKNYPNKKQLTTRPFAGMIEEMIYFY
                     QLEAENLSNYGKLFEQAFYLTENGHLLSASMKKFLGMMFHFVWNLQAYPFDFQLKNFF
                     VWLDLLGYPIHWLEQISKMEYLEKVLFLAEKSKKILVLEKIGIIDGYQHPNEKELLRT
                     MTVFQQIVSEIRGN"
BASE COUNT         1799 a         1338 c         1103 g         2222 t
ORIGIN      
        1 aaatcttgtc acagtccctt attctgaata aacggtgtgg aagagacagc ctatcagtag
       61 taataagaca catctctttc acagcctcat ttttgcgtaa aaatcgattt attcgaaaaa
      121 ttccccgtat acatcttcta cacgttgatc tggattgatc acgatataca agttacctgt
      181 tttttcgctg atttttgttg attgatattg attgtctaat ccttctgttc ctttatctag
      241 atatgggaag tacacaagat caggtgtgcc atttcggtaa aggatttcca ttcgctcgat
      301 atcttcgtat ttcaatgcgc gattaaacat gcccatttcc agtccgccta ggttgatatc
      361 atgtgtcgca actgcgtccc cttcatggaa gatttcgatt ttaaatccag cacacggatg
      421 gatttcaaca aattcactgc cattgattcg tccaaaactt gttgtgattt gtttgatcca
      481 aagatcgccg atatgacggc ggttgatcgt ccaggtttct ccatttctaa aataaaattt
      541 tagcgctgtc atttctttac tcattaaaaa gactccttta tgatgtaatt tattcttgta
      601 ctacctcagt ttagcacaaa tttatgtaag tggtcacatc ttatgttttt tcttctaatg
      661 acgtatctgc ccactttaag tagccaacaa agctgagcag atacagtcta gtgtttttta
      721 aatcaatttt tctttcgata aaaaatccaa aacctgtttt ttatcatttt ttattctttg
      781 ttctacgacg gctttttcag ctaattgcaa agcttcacta acccacttac caggtttttt
      841 tccagtttct tctagcaaga ttttaccatc tactgctaat tcgcttaatg acttgatagg
      901 taaacgatca taggattctc ctacggcatc catctgaggt gtttcgtcaa aatagatcat
      961 caattcttct acttgcagtg catgtttttt gcctaagaag tacaattcga atggttccaa
     1021 agctccagtt tctcgttgtc gtagtccttg gacaagtgct tgaacgtctt gaatcatttg
     1081 gttagaacac ttccacgatt tcaaaaagga acgaatctca ttttctttta gatccagttg
     1141 gctgatcaat aatgcccatg cttggctctc ttctttcaat gggacggatg gtaattcagc
     1201 aaaacgtaaa agtgcttcgc cttcttcttt caaaccggga cagcaaatgt agcactctgt
     1261 ttcaataaat gcatggattc ccgcggcccg ttcatttccc aagagcatct tgatgaattc
     1321 cacatttata cgttctacag atattttacc taatagctcg tggttttctt tgatggcgta
     1381 gaaggtttct tcctctaatt tgaaccctag ttgactgaca aaacgcaacc cgcgcatcat
     1441 tcgtaaggca tcttcatgga accgctcatg aggattgcct acagctcgca agatctgttc
     1501 ttctagatct tgcagaccat cgaacaaatc gatgatttct ccatcttctt tcaaagcaaa
     1561 cgcattgatc gtaaaatctc ttcttttcaa atcttctgcc aacgaacgaa cgaattcgac
     1621 atgatctggt ctacggtagt cctgataagt tgattccgtc cgaaatgtgg tgatctcata
     1681 ttgttcatca ttttctaata ccaacacagt tccatgttcg atcccaatat ctatcgtttt
     1741 tggaaaaagc tgtttgattt cttctggaaa tgcgcttgtt gcgatatcca catcatggat
     1801 tggctggttc agcaagatat cacgaacact tccacctaca aaataagctt catatcctgc
     1861 attctctaat tttttcagaa ctggaattgc cttttggtat tccagaggta attgttttaa
     1921 tttcattttt ccaacctttc ctgcgtgttt cttgtcctga gataaagact cagttgcatg
     1981 gtgactgttt gacaagtccg tttcagagtc ttcaaggcca ggaccacttc atcttgttta
     2041 ctcgtcctta cgctcaaagc gattatggtc tctttgattg aatttttcca tgtttttttc
     2101 aaaaacttca gttaagtcga tattcaatga attagccatg atcatcgtaa cgaataaaac
     2161 atcaccaagt tcttctgcta ccgagttaac tggttcagaa gcctttttgc ttttttctcc
     2221 ataagtgtgg ttgacttctc ttgccaattc acctacttct tcagttaatc gagccatctg
     2281 agctaatgga gagaaatacc ccaccttgaa ttgctggata tattcatcca cttcctgctg
     2341 catactgtat aaagaacgct ttttatccat ctttttccct ccaaaactat cttaccaaaa
     2401 ctttaacgca aatcctagat aagagcactt gagaaaatcg aatttccatg ctacatttag
     2461 gaaggaattt ctaaatggaa attctgtgaa aatacataat tgaaagctgg aattcatatg
     2521 gtcaaacgaa aaacagtaaa agaagttctt tttatcatta taggaacaag tatttatgca
     2581 tttggtcttg tttacttgaa catcgctaat catttagcag aagggggagt ctcagggatc
     2641 accttgatct taagagcttt atttggtatt gatccagctt atacgacttt attaatcaac
     2701 atcccattga ttttactagg aggaaagatc ctcggtaaac gttccttggc ctatactgtt
     2761 ctaggtacac tttctttgtc attcttttta tggatctggc aaagggttcc actagaaatc
     2821 aatttacagc atgatctact gatcgtttct ctacttgcgg gtttagttgc aggtgtagga
     2881 agcgggatcg tctaccgcat gggtggaaca acaggcggca gtgatattat cgctcggatt
     2941 ttagaacaaa attacggcat cactatgggg cgttccctat tggcatttga tatcatcgtc
     3001 ttacttgctt cattaaccta tatcgacttg aaacgtatga tgtatacgtt gattgtttcg
     3061 tatgttttca gtcgtgtgat tgattcgatc ttagatggcg gatattctgc aaaaggtcta
     3121 cttgtcgtct ccaacaaaag cgaagagatt gcaccactac tgatgaccgg tctgcaaaga
     3181 ggtgtgactt tcctttctgg agaaggcgca ttctctggta attcaaaaaa aatcatctat
     3241 atggtcgtta gctctagtga attaactgaa gctaagagga tcgtccacga gattgacgaa
     3301 aaagctttcc tttcaatcat caatgtgcat gaagtggaag ggcaaggctt tacttatttg
     3361 aagccacaga caagattact gaaaaaacta taagaaaaaa gacaaagata ggctatgagg
     3421 aaagattcca catccagctg acctttgtct tttttagtac tatactattt ttaactaatt
     3481 gttatgttca cttacccggt tacttttctt ttgtgtctgc aaaaggatct ttcggttaac
     3541 ttcatcagat aatttcaaaa aagcatccct atctccatct tctagtgctt gatcgatttg
     3601 agcataaagc atttttagtt ttgcctcttc ttctttttct tgaaaatatc gttcaattaa
     3661 ttcagtatct tcttcactga ctgaagaatc ccaagaagaa aatggattgt cttctaagat
     3721 agatagatat tctcttgtct gccaagcatt ttcgaatata cattccacat ataaaggctt
     3781 tttccaattc aaacggattt catgaaaaat ctggtctgtg tccgtaaatt cttttccctg
     3841 caaaaacaat ttcatgggtt ccccttcaac agatagatca ctgatctgca gtcctcgatc
     3901 cgcaaaattc gccccttcaa caaagtggac attgcttaaa atcgcttcat gattggcaag
     3961 ataattcaag atccaaaaaa cttctcttcg gctaaaagat acatgattga ccatccacgt
     4021 taaaaaattc ttcttttccc gtacatcaat tagcattttt ctcacctctc tgttaggtca
     4081 tctaataatg acagtgcctc catatctcct ggttcaagtg ttaaataata agtcaataat
     4141 tcttgcgctc ttttcagctg cccttcttct cttaagaaaa aggcatactc tttcaagaaa
     4201 tctggttcat gtgatagttc atgataagcc tgttcatagt gtacagctgc aacggtaaag
     4261 tcttctaatt cattataagc atgggctagg ttccattctg cataaggatt agcagtttct
     4321 tccatctgat tgatcacttg tatcacatct tcatatcttt catcatccaa gtaaagatta
     4381 cttaaagtaa gtaatgtttc atcttgtttg tctcctactt ctaaagcttt cagtaaaagt
     4441 tcttctgctc gctgtctatc atgcagacgg aaagcatttt ccgaggccag gtgataaagt
     4501 tcgacttggt aaggattttc tttgattcct tcttctaaca ctgtttgtgc ttcttcaatc
     4561 atttcttctt cttgaagagc ttgtcctaga tatagatata acgattgata atgcggatta
     4621 acttctcgaa gttcttccag atagttgatt gcctgctgat tttctttcaa ttgaagattc
     4681 gtaaaagcta gctggaacag tcgatcatct gtcctttctt ctttcagtgc ttcttctaaa
     4741 ggtacgatag ctgcttcgaa ttctccttgc atacttaagg attgtcctaa acgttcctgc
     4801 atcgagattc ctgaaatttc atttatcccg cttgccaaca atgtttcata aaccactgct
     4861 gcctctttga aacgatcaac tgaaaaatac aattcagcta gcgcaaactg gatcaatggt
     4921 tcatcaggaa gcaacccagc tgcttctttc aattttgctt cactcacttc agggattccg
     4981 ataacttggt acaaatcagc tatcgccaat aagctttgcg gatagtaatc actttgctta
     5041 tccacttttt ccaggtattc aaaagctaag tcgatctcat tatcttcgat tgcaatttct
     5101 gctaacggga tgttcagtcc gtcattttct gggtattggt tgatcagttg ttcaaaaatc
     5161 tgttttgctt cgatcaaaaa gccaatagcc agcaattctt cgcctagttc agctaatata
     5221 tctgctgggt cttcttttaa tgctttttct aaaaagattt gtgcttgtga caagtcttca
     5281 tctgataaag cttgcaacat tttttcgcta tttgtattca tttcaattcc ctcttatctc
     5341 actgacgatt tgttgaaata ccgtcattgt tctcaataat tctttttcgt ttggatgttg
     5401 gtatccgtct attataccta ttttttctaa aacaagtatt tttttgcttt tttctgccaa
     5461 aaaaagaact ttttccaaat actccatctt tgaaatctgt tccagccagt ggattggata
     5521 gccaagcaag tccagccaca caaaaaagtt ttttagttgg aaatcaaaag gatatgcttg
     5581 gagattccac acgaaatgaa acatcattcc taaaaatttt ttcatactag cagaaagtag
     5641 atggccattt tcggtcagat aaaaagcttg ttcaaacagt ttaccataat ttgacaggtt
     5701 ttctgcctct aattgataaa aatagatcat ttcttcgatc atcccggcaa acggccgagt
     5761 cgttaattgc tttttatttg gatagttttt atacagattt tgcaaaaaac gatgatcaca
     5821 aatcattccg caacagataa aagtcaaaaa gtcaatctgc tttccgtcca cctgccgctc
     5881 gctgattgtt tgatcataaa cgatgcgttc tggcagattg atggtttgca gcactacacg
     5941 atttggtagc tgcaaaatcg tccgctgcgg tgttaatgct cggcttagag aacggatcga
     6001 tacagggatc atccatagtg atgaatcaag ggttgtatgt ttttgaaaaa aacctgccag
     6061 atccatgatc ccttcatttc caaatccgat gataaacatg gattgatttt cgggatagcg
     6121 tttgacgaaa tcaagcaggt tctttaattc tgttaaatga ttgcattgag tgttggcaca
     6181 aatataccag tcattgtttg cttgatttgc aaataacggg ttgatcttat ctgcaaacaa
     6241 atcataatag cgctgattcg ttaaaaataa gattggctga tcaatggaaa gttctcttag
     6301 ctgactgact agcgtttctc cgtaaaacac tttcgtcaac gcatcttcta cttgataatc
     6361 aagttccata cgcatccctc ctcttcttat ttttatttta ccattagtaa gcaaattcta
     6421 gaaaagataa gagcaaagct cacctcataa cttggaaata aa
//
LOCUS       DAFBVQ010000097         6328 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.102, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000097 DAFBVQ010000000
VERSION     DAFBVQ010000097.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6328)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6328)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6328
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.102"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            127..579
                     /locus_tag="LLC22_002632"
     CDS             127..579
                     /locus_tag="LLC22_002632"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000751236.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435842.1"
                     /translation="MKKTILSIFSVFTILIGGYFLLNLDSVNSNAQIKDQRVAEHNNK
                     KMSLTKNIYSMSDEELYKEFGDLSGEQLEESIPGISDSDKIVVLSAGGQLMGDGKSEL
                     VSYKQNHRQFIDVNTDSNAISIKDLKELLNSKRNELKQIKETNSVELE"
     gene            593..1282
                     /locus_tag="LLC22_002633"
     CDS             593..1282
                     /locus_tag="LLC22_002633"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000718009.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435843.1"
                     /translation="MKKIFGVSVGLLMMLTFGNAVYAAEKEVISDPEQYASRYFADFE
                     EEDKVLALPEGGFLKGEAKIVSMDNPDIIQGSYNSETDPASVSVTEAKKIVAEKFKND
                     IETTPIMPRGAFPPDVGTSGHLLVLAGGGSYKSQPFSGAGWRFGGMGVKPADGTGNFL
                     RWKSYIDDGRVGNVNQANATKSGSIQGMALYAREGFKYFAPNGPGWTMNIGIYYTYNP
                     VAGTYYVVQNI"
     gene            1407..3758
                     /locus_tag="LLC22_002634"
     CDS             1407..3758
                     /locus_tag="LLC22_002634"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000344083.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1906 domain-containing protein"
                     /protein_id="HBK5435844.1"
                     /translation="MDEMVLSTQKWLNKKYSNVTGFDKVPENGRTGWPTIYGLIEGLQ
                     VELGITNLVANFGPTTEKMYDNQVTPKWGKNLPKNIVFLIQGAFWCKGINPGGFDGVY
                     TPYLDTAVKELQTDAGFNGSAVTGVLDAKWAKALFDMSAFVLVPGGDSKIRKMQQWLN
                     VNYLEYTGIMPCDGIYQRNSNQALIFALQAELGYSPSEATGSYGNGTTSKTYPVSEGN
                     SGNYVRIIQYGLYVNGYFEDGTFDGIFTKYMGLEVLAFRKFMVLPEYTEIADVVVIKG
                     LLSSAGDIRRSADGADTSTQLTRSQIQTLVDNDIKIVGRYLTGTVGIGKDERNKYLTT
                     EELNNIFSKNLSVFPIYQDGGAALAYFTYDRGLSDGKKAIDAAKNLNIPLTTVIYFAV
                     DLDMLGEEILAYAGEYFKGVSAVMSYSGYQTGVYGTRNVCSQIINNGYASFAFVSDMS
                     TGYSGNLGFPMPRQWSFDQFVEFTIGSGNGAVGIDLIATSGRDSGFNELSNDTNNDNY
                     IAKYNQKVINQMVRAYQYLSQAGLDNPWNPHLTFYRYVNYSGLSWDIISSPVTEHDRK
                     IYDEYRNKLTNSEGLYNYFIDPNTGSIIGLPHLIVTLQSQMFLADTINDSVSDFAGWL
                     GDLMTCWGEVKKLGIQMEQGVFALVGTAAGGTFSLEDLYQDVDAVNVYTLAKRNSDST
                     ALSALKTYYCDKGAIDRFNQFVKNRFGSSDKIASVTNSLLENDETVDILGVGIISFFI
                     DKIVNNSLGTDFTYLDFIGDEGKVANGFSEKIIQFQENRSKLN"
     gene            3838..4233
                     /locus_tag="LLC22_002635"
     CDS             3838..4233
                     /locus_tag="LLC22_002635"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435845.1"
                     /translation="MMIMEEIEWNNLTQNNKNNSGCGIIFMFVIVLGIVVLLITVKIV
                     DYFANTPEEQIQRKLPEFERVPPYDPRDNSFQVKKLKESPNEMWFEVTVESSDFKEKK
                     KEYNYIVKAKVSKRFIFNPKLEIYSVVIE"
     gene            4558..5175
                     /locus_tag="LLC22_002636"
     CDS             4558..5175
                     /locus_tag="LLC22_002636"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001224538.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5435846.1"
                     /translation="MRKFFYIRVSSYDQSIERQLISAKELGIPEEYIFVEKASGKDFK
                     RPEYQLMKRMFRKGDLLYLQSLDRLGRNKQMILEEWRELTKEKQIDISVLDMPLLDTA
                     SYKQLDGLETLISDLILQLLSYMAEDERKRINSRQREGVEAAKQKGVKFGRKKIALPP
                     EFPAIYSDWKAGKITAVYAMDQLGMKRNTFYRRVKEYEHTLHHFS"
     gene            5216..5515
                     /locus_tag="LLC22_002637"
     CDS             5216..5515
                     /locus_tag="LLC22_002637"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000366408.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="BRCT domain-containing protein"
                     /protein_id="HBK5435847.1"
                     /translation="MDLTNQRVVFTGTLQQMTRTQAIGLVHSLNGHCQSSVTSKTNFL
                     VCGQYSKSLFDDSLYTKKEQTARDLIALGHEITILSEVEFYALISQQLKEWQRYL"
     gene            5549..5716
                     /locus_tag="LLC22_002638"
     CDS             5549..5716
                     /locus_tag="LLC22_002638"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000824191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator"
                     /protein_id="HBK5435848.1"
                     /translation="MKRKSYDRWGIEITSFNRNIAFHVECDCGELAKSVYQKNYFYCP
                     KCHRRYGVHGT"
     gene            complement(5761..6324)
                     /locus_tag="LLC22_002639"
     CDS             complement(5761..6324)
                     /locus_tag="LLC22_002639"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304893.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5435849.1"
                     /translation="MIFKLRNRTEGLNIDKLFQEKASGKDTERPEFQKLLNYIREGDC
                     VIVTSLDRLGRDYEDIKNTVAFMKQKKVALKILDAQFLDFNTGNELLDTAMFDMFLSL
                     LSYIAQNEREKIRERQRQGVLLAQKAGRYKGRPIEYSINSTDPQKRLVFKTVVDMLKQ
                     GIPVAEIAKENGISRPTIYKIKKANDL"
BASE COUNT         2171 a          878 c         1258 g         2021 t
ORIGIN      
        1 attcctcctg ctatcttttt ctattattct atcttatttg atagtagatt taaaactttg
       61 caacagaacc aattatctta tcgtagatat atattataaa tttaataaga aagcgaggtg
      121 agaatcgtga aaaaaacgat actaagtatt ttttcagtat ttacaatatt aattgggggc
      181 tattttcttt tgaatttaga ttctgttaat tcaaacgctc aaataaaaga tcaaagagta
      241 gctgaacata ataataaaaa aatgagtttg accaaaaata tctattctat gtcagatgaa
      301 gaattgtata aagaatttgg tgatttatcc ggggaacagt tagaagaaag tattccagga
      361 attagtgact cagataaaat tgttgtcttg tctgctggtg ggcaattaat gggagatggc
      421 aaatccgaat tagttagtta taaacaaaat cacagacagt ttattgatgt taatactgat
      481 tccaacgcta tttcgattaa ggatctaaaa gagcttttaa atagtaaaag aaatgaatta
      541 aagcagataa aagaaactaa ttcagtggaa ttagagtaaa ggaagattca ttatgaaaaa
      601 gatttttggt gtttctgttg ggctacttat gatgttaaca tttggaaatg cagtatatgc
      661 tgctgagaaa gaagttattt cagatccaga gcagtacgcc tcacgatact ttgctgattt
      721 tgaagaagaa gataaagtac ttgcattgcc agaaggtggt tttttaaaag gggaagctaa
      781 aattgtatct atggataatc cagatataat tcaaggttca tataattcag aaactgatcc
      841 tgcttcagtt tcagtgacag aagcaaaaaa aattgttgct gaaaaattca aaaatgatat
      901 tgaaactact ccaattatgc ctcgaggagc atttccaccc gatgttggta ctagcggaca
      961 ccttcttgta ctagcaggag gaggaagcta taaatcacag ccatttagtg gtgcgggatg
     1021 gcgttttgga ggtatgggtg taaaaccagc tgatggtaca ggcaactttt tacgttggaa
     1081 atcctacatt gacgatggaa gagtaggaaa tgtaaatcaa gccaacgcaa ctaaatctgg
     1141 ttctattcaa ggaatggcat tgtatgctcg tgaaggattc aaatactttg caccaaacgg
     1201 gcctggttgg acaatgaata taggtattta ttacacttat aatcctgttg caggtacgta
     1261 ttatgttgtt caaaatattt aataaaacag cacaaagaga tttctttgtg ctgttttatt
     1321 atttttagtt gttgacaaac actaaaatat aaaatataat caacacataa acgaacgtat
     1381 gttcggcaag aaagcagggg atttttatgg atgagatggt tttaagtact cagaaatggc
     1441 taaacaagaa atacagtaat gttacagggt ttgataaggt tccagaaaat gggcgaacag
     1501 ggtggcctac aatctatgga cttattgaag gactacaagt agaacttggt attactaatc
     1561 tagtagctaa ttttggacct accactgaaa aaatgtacga taatcaggtt actcctaaat
     1621 ggggcaaaaa tctacctaaa aatattgtat ttcttattca aggtgccttt tggtgtaagg
     1681 ggattaatcc aggtggcttc gatggggtat atactccata tttagatact gctgtaaaag
     1741 agttgcagac tgatgcaggg tttaatggaa gcgctgtaac tggagttttg gatgcgaaat
     1801 gggccaaagc gttatttgat atgagtgctt ttgttcttgt tcccggcgga gatagtaaaa
     1861 ttagaaaaat gcagcaatgg ttaaatgtaa attatttaga atacacggga ataatgcctt
     1921 gtgatggtat ttatcaaaga aattcaaatc aagcattaat ttttgcatta caagctgaac
     1981 taggatattc tcccagtgaa gcaacagggt cttatggtaa tgggacaact agtaaaactt
     2041 atcctgtgtc tgaaggtaac tcgggaaact atgtaagaat aattcaatat ggattatatg
     2101 ttaatggtta ttttgaagac ggtacattcg atggtatttt cactaaatat atgggtttag
     2161 aagtactggc attccgaaaa tttatggtat tgcctgaata tactgaaata gcagatgttg
     2221 ttgtaataaa aggactattg tctagcgctg gagatattag aagatctgca gatggcgcag
     2281 atacttctac gcaattaact agatctcaaa tccaaacatt ggttgataat gatataaaaa
     2341 tagttggtag atatcttact ggtactgttg gaattggaaa agatgaacga aataagtatc
     2401 taactacaga ggaattgaat aatatttttt ctaaaaattt atctgtgttt cctatctatc
     2461 aagatggagg tgcagcatta gcttatttta cttatgatcg tggcttatca gatggtaaga
     2521 aggctataga tgcagcaaaa aatctaaata taccattaac aacagttatt tattttgctg
     2581 ttgatctaga catgttaggg gaagaaattc ttgcatatgc tggagaatat tttaaggggg
     2641 tatctgctgt aatgtcatat agcgggtatc aaacgggtgt ttacggaaca agaaatgttt
     2701 gttctcaaat aatcaataac gggtatgctt cgtttgcatt tgtttcagat atgtcgactg
     2761 gttatagtgg gaatttaggt tttcctatgc ctagacaatg gtcttttgat caatttgttg
     2821 aatttaccat aggaagtggc aacggagctg ttggtatcga tttaatcgct acatcgggta
     2881 gagatagcgg atttaatgag ttatcaaatg atactaataa tgataattac attgccaaat
     2941 acaatcagaa ggttataaat cagatggtac gtgcgtatca atatctatca caagctggtc
     3001 ttgataatcc ttggaaccct catttgacat tttatagata tgtaaattat tctggtttgt
     3061 catgggacat catttcttct cctgtaacag agcatgatag aaaaatttat gatgaatata
     3121 ggaataaatt aactaatagc gagggcctgt ataattattt tatagatcct aatactggtt
     3181 caataatagg tttgcctcac ttaattgtga cgttacaatc acagatgttt ctagccgaca
     3241 caatcaatga tagtgtttct gactttgcag gttggttagg agatttaatg acttgctggg
     3301 gtgaagttaa gaaattagga atacaaatgg agcaaggtgt atttgcatta gtaggtacgg
     3361 ctgcaggtgg aacatttagt ctagaagatt tataccaaga tgttgacgcg gtaaatgttt
     3421 ataccttagc aaaaagaaat tctgattcaa cagctttatc ggctttaaaa acgtactatt
     3481 gtgataaggg tgctattgat agatttaatc aatttgttaa gaacagattt ggttcttcag
     3541 ataaaatcgc ttcagtaaca aatagtttat tagaaaatga cgaaacagtt gatatcttag
     3601 gtgtagggat aatttcattt ttcattgata aaatagttaa taattcactt gggacagatt
     3661 ttacttatct tgattttatt ggagatgagg ggaaagttgc aaatggattt tctgaaaaaa
     3721 ttattcaatt tcaagaaaat agaagtaaac ttaattaaga atcgtttact atttaaacag
     3781 tgtccttttc ctttttaaat atatacgata aaataagtat atgaattgta aaaggacatg
     3841 atgattatgg aagaaataga atggaataat ctgactcaaa ataataaaaa taattctgga
     3901 tgtggaatta tctttatgtt tgttatagtt ttgggaatag tagtactttt aataactgtc
     3961 aagatagtag attactttgc gaatactcct gaagaacaaa tacagagaaa acttcctgag
     4021 tttgaaagag taccacctta tgatccaaga gataattcat ttcaagtaaa aaaattaaaa
     4081 gagtctccaa atgaaatgtg gtttgaagtt acagttgaat caagcgactt caaagaaaaa
     4141 aagaaagaat acaattatat tgtaaaggca aaagtatcaa aaagatttat ttttaaccct
     4201 aaattagaaa tatatagtgt tgtaatagaa taatagtgtt aaaaaaattg taaaagttaa
     4261 agaagtcaaa ttctgatgtg aaaaataaaa tataccatgg aagacataaa agaaaaactg
     4321 gataactagt ttatttaatg gcagaccgtt aaggcctgcc atttttatgt attttagcgg
     4381 aataaatata atcatgcggg agtgtaaact tactgtttca aaaagtatac tttttgacat
     4441 gccttgattt tctttgttta tgtatggcat aataaccaca taatacaatt tgaaacgttt
     4501 ctgatttaat ctgattgttt tgaaacaatt ttagtgaaaa aagggtagat aaaaacgatg
     4561 agaaaatttt tttatatccg ggtcagtagt tatgatcaat cgatcgaacg acaactgatt
     4621 tccgcgaagg aattaggaat ccctgaagaa tatatatttg tagaaaaagc cagcggcaaa
     4681 gattttaaac gccctgaata tcaattaatg aaacggatgt ttcgaaaagg agatttactc
     4741 tatctacaat cattagatag actaggcaga aataaacaaa tgattttaga agaatggcga
     4801 gaattaacta aggaaaagca gattgatatt tctgtgttag acatgcctct gttagatact
     4861 gctagttaca agcaactaga tgggttagag acgcttatct ctgacttaat tctgcaatta
     4921 ctcagctata tggccgaaga cgagcggaaa cgaattaata gccggcaaag agaaggcgta
     4981 gaagctgcga aacaaaaggg tgtaaaattc ggcagaaaga aaattgcttt acctcctgaa
     5041 tttcctgcga tctattctga ctggaaagca ggaaagataa ctgcagtcta tgctatggat
     5101 caattgggca tgaaacgaaa taccttttat cgacgggtga aagaatatga acataccttg
     5161 caccactttt cttgatagat ataacagcta ttagacggga agggagagtt tgaaaatgga
     5221 cttaacgaat caaagggtcg tttttactgg aacgctgcag caaatgacac gaacccaagc
     5281 catcggtttg gttcactctt taaacggcca ttgtcaatca agtgttactt caaaaacaaa
     5341 tttcctggtt tgtggtcagt attctaagtc gttgtttgat gattctctct atacaaaaaa
     5401 ggaacaaacc gcgcgggact tgattgcgtt aggtcatgag attaccattt tatcagaagt
     5461 cgaattttat gcgttaatta gtcaacagtt gaaagaatgg caacggtatt tataatcgtt
     5521 agtaaaattt acaaggagga aaatttttat gaagcgaaaa tcttatgatc gttggggcat
     5581 tgaaataact agttttaatc gaaatattgc ttttcacgtg gagtgtgact gtggggaatt
     5641 agcaaaaagt gtttatcaaa aaaattactt ttactgtcct aaatgccatc gccgatacgg
     5701 ggtacatgga acatagaaac gaaatagtgc ggtagaaaag cgaatgaatg tagtatattt
     5761 ctacaaatca ttcgctttct ttattttata aatagttggt cgagagatcc cgttttcttt
     5821 tgcaatctct gcaactggaa tgccttgctt taacatgtcc accacggttt taaaaactaa
     5881 gcgtttttgc ggatctgttg agttaataga atactcgatt ggtcgtccct tatatcggcc
     5941 ggctttttga gccaataata ctccttgccg ctgacgttca cgaattttct cacgctcgtt
     6001 ttgtgcaata taacttagca gtgataaaaa catatcgaac atagcggtat ccaggagttc
     6061 atttccagta ttaaaatcta aaaactgtgc atctaatatt tttaacgcta cttttttctg
     6121 tttcataaaa gcaactgtat tttttatatc ttcataatct cttcctaaac gatctagtga
     6181 tgtaacgatg acgcaatcac cttcacggat ataatttagt aatttttgaa actcaggacg
     6241 ctcagtatct ttaccactgg ctttttcttg gaataattta tcaatgttaa gtccttcggt
     6301 tctgttgcga agtttgaaaa tcaaacgc
//
LOCUS       DAFBVQ010000098         6287 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.103, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000098 DAFBVQ010000000
VERSION     DAFBVQ010000098.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6287)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6287)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6287
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.103"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..177
                     /locus_tag="LLC22_002640"
     CDS             <1..177
                     /locus_tag="LLC22_002640"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435850.1"
                     /translation="QSLVLLAIVVIGLFLGFKREFSKLIGFLVIALIAVGLVFNASGV
                     KDVLLNLFNRIVGA"
     gene            190..691
                     /locus_tag="LLC22_002641"
                     /pseudo
     CDS             190..691
                     /locus_tag="LLC22_002641"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288934.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
     gene            788..2635
                     /locus_tag="LLC22_002642"
     CDS             788..2635
                     /locus_tag="LLC22_002642"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288935.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PHP domain-containing protein"
                     /protein_id="HBK5435851.1"
                     /translation="MVGNKWYKCDLHIHSTASQCFQDKKVTAKEWVEECLNKGLDCVA
                     LTDHNTGENIDEYKKVAIENGLDFFPGVELTCGENGTHLLVLFDKSACTNDISDFLTK
                     MGIKREDWASAAACSMKSVLEVIDFAEHEGLLVIPAHIDEFNGISSAKFGNLGKIFES
                     ENIYAVQTVQKEFFENRSQMIPSSKRDTIYDSVNARYDGRVGKDTLESWYKSVVEAEK
                     NNMTFLSFSDNPHSKGNSKHGLWGIGTRYSYIKMKDEPDLGSLRDALMLGETRVHSDF
                     SNFSINENEVLLEKLSFSGTTLSTKEVVVEFSDNLTSIIGGRGTGKSCITRFLVYVLG
                     KEAELDQFSEIQSDYQNFAQIEHNGSGIFLKDTIVKLNIFYKGTKYQIIRTQDRHSIY
                     EFTQENGLVEKETERLRMISDKVSIYSQKQIYEISKNQTSILELLDGYNSDLISEYKN
                     EIETCVNEIRKLNWDIVSVKKEIQDKAKVELEIEDLKKQVEKLSHKSYKDVYDEYSKE
                     TDIYRELKRDVEALKEIPKNLTDSVDKIDFGNGIKVTDEIDEHRGELIKNLVTNRAKI
                     QTIINEMSDEIDSYRAELNKSDWKVNYNEVSKRYQRGIKNLVKSYLKMN"
     gene            2638..3534
                     /locus_tag="LLC22_002643"
     CDS             2638..3534
                     /locus_tag="LLC22_002643"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305705.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5435852.1"
                     /translation="MLQNLDSLYQSLSKTEERLEEIIQQEIKLKDYQVEVDSAMSRMN
                     KSYQNLYSERSSSSREIFSDITGIEATIQPNRDFNNYVKELRACINKEDTFDSEFGSL
                     IDKLTKNSITNQDIYNDILDIRVSGESSIFSDKKLINSIRKLNDAQVLELQTLKPNDL
                     VVIRLELNGKKVSLSNASAGQKTSAILSMILAYGNSPLILDQPEDDLDSQLINNLIVR
                     SIITKKENRQILIVTHNANIPVNGDSEWLISMGDSKEISADQCGSVDEPNIKPRICTV
                     MEGGEDAFTNRAKRYGFKQIVE"
     gene            3584..3973
                     /locus_tag="LLC22_002644"
     CDS             3584..3973
                     /locus_tag="LLC22_002644"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5435853.1"
                     /translation="MKKIKSYTSIWAVEKVIYAINDFQLPFPVTFNQMAWFVLSLLFV
                     IVFAHVPPLSMIEEVFLKYLGIPVAVTWFMSQKTFDGKKPLGFLRSFISYHLRFKVTF
                     AGKKVKEQKKRWDEPSTLVRSVNYVSD"
     gene            3960..>6287
                     /locus_tag="LLC22_002645"
     CDS             3960..>6287
                     /locus_tag="LLC22_002645"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335929.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5435854.1"
                     /translation="MYPIKYIENNLVFNQEGECFAYYELVPYNYSFLSPEQKFQVHDN
                     FRQLIAQNREGKIHALQIATESSIRATQERSKKEITGRLKEVAKQRIDIQTEALVSMI
                     GDSQIDYRFFIGFKLIATDEEVNLKSLKKSFFSGLQEFVYGVNHHLMGDFVSLSNEEI
                     RCYSKLEKLMESKLARRFKVRRVTPSDLTYLIEHIYGEKGIPFEEYEFQLPKKKLKSE
                     TLVKRYDLLRPNRCLIEEKPRCLRMEHENHESYVAYLTINTIVGEMEFPSSELFYYQQ
                     QQFTFPIDTSMNVEIVTNKKALATVRNKKKELKDLDNHAYQSDNETNSNVLDALDSVD
                     ELETTLDQSKESMYKLSYVVRVSAESVDELKRRCDEVLDFYDDTNVKLVRPFGDMMGL
                     HEEFLPSSKRYMNDYIQYVTSDFLAGLGFGATQMLGELEGIYFGYNVDTGRNVYLKPA
                     LASQGVKGSVTNALAAAFLGSLGGGKSFSNNLLVYYAVLFGGQAVIVDPKGERGGWKE
                     TLPEIADEISILNLTSKSENQGLLDPYVIMKKKKDSESLAIDILTFLTGISSRDGEKF
                     PVLRKAIRTVTQSDQRGLLQVINELRKDGSPIAENIADHIESFTDYDFAHLLFSDGSI
                     TQSISLDKQLNIIQVADLVLPDAETTFEEYTTMELLSVSMLIVISTFALDFIHSNREI
                     FKIVDLDEAWSFLQVAQGKTLSNKLVRAGRAMNAGVYFVTQNSDDLLDERLKNNIGLK
                     FAFRSTDIHEIKKTLEFFGLDQEDQSNQKRLRDLEN"
BASE COUNT         2118 a          933 c         1349 g         1887 t
ORIGIN      
        1 caatctttag tcttactagc gattgtggtc attggtttgt ttttaggatt taaacgcgag
       61 ttttccaaac tgattggctt cttggtgatt gctttgattg cggtaggtct ggtctttaat
      121 gcttctggtg tgaaggatgt cttactcaat ttgtttaacc gaattgtcgg tgcctgaggg
      181 ggaatcacaa tggaacagat acgtgtttat attgcgaacc ttggaaaata caatgaaggt
      241 gagttggtgg ggggcatggt ttaccccacc cgtcgatttt gatgaagtga aagaacggat
      301 tggattaaat gacgaatatg aagagtacgc aattcatgat tatgaactgc cttttgagat
      361 tgatgagtat acaccaattg aggaaattaa tcggttgtgt ggtttagcgg aagagcttaa
      421 aggaacgcca attggtgagg tcgcttcaga gattcaacat gccttcttca attctttcga
      481 ggaaatggta gagcatgtgg atgatatcat ctattatccc gattgtaatg acatgagtga
      541 tgtagcgtat tacttgattg tagaagctgg tgatttaggc gaagtaccag aacacttgaa
      601 gacgtatatt gattttgatg cgtgtggtcg agacttggag attggcggga attatttggt
      661 tacgagtcga ggggtttttg aactaatgta aatcatttgt tagaattgac cagaaatttc
      721 tatcgtactt ttacttttct atttgatata ctgaaataga aaatatttgt tgataggggt
      781 gttactaatg gttggcaata agtggtacaa atgtgatctt catattcatt caactgcgag
      841 tcagtgcttt caggataaaa aggttactgc taaggaatgg gtagaagaat gtttaaacaa
      901 aggactcgat tgtgttgcat taactgatca caatacaggg gaaaatattg atgaatataa
      961 gaaagtggct atcgaaaatg gcttagattt ttttcctgga gtggaattaa cgtgtggaga
     1021 aaatggaact catttactag tcctatttga taaaagtgca tgtacaaatg atatctctga
     1081 tttcttaacc aagatgggta taaaaagaga ggattgggcc agcgctgcag cttgctcaat
     1141 gaaatcagtt ttagaagtta ttgattttgc tgagcacgag ggcttgctcg ttattcctgc
     1201 acatatagat gagtttaatg gaatttcttc agcaaaattt ggaaatctag gaaagatatt
     1261 tgaatcagaa aatatatatg cagtacagac ggttcaaaaa gaattttttg aaaatcgctc
     1321 acaaatgatt ccctcatcta agcgtgacac tatctatgat agtgtgaatg ccagatatga
     1381 tggtagagtt ggaaaagata ctttggaatc ttggtataaa tcagttgttg aggcagaaaa
     1441 aaataatatg acatttctta gcttttctga taacccacac tcgaaaggaa attcaaaaca
     1501 tggactttgg ggaataggca caagatattc ctatataaaa atgaaggacg aacctgactt
     1561 gggatcactt cgcgatgctt taatgctagg cgaaactcga gttcattctg atttttctaa
     1621 tttctccatt aatgaaaatg aagttttatt ggaaaaatta agcttttctg ggaccactct
     1681 tagcacaaaa gaagttgtag tcgaattcag cgataattta acttcaatta ttggaggaag
     1741 aggaacaggc aaatcttgta ttacaagatt cttggtctat gtccttggaa aggaagcaga
     1801 acttgatcaa ttttctgaaa tacaaagtga ttatcagaac tttgcacaaa ttgaacataa
     1861 tggctctgga atatttttga aggatacaat tgtgaaactg aatattttct ataaggggac
     1921 aaaatatcaa ataataagaa cacaggatag acattctatt tatgaattta cacaagagaa
     1981 tggtctggtt gaaaaagaaa cagaacggtt gagaatgatt tccgataagg tgagtatata
     2041 ctctcaaaaa caaatttatg aaatttcaaa aaatcaaact agtatactag aattactaga
     2101 tggatataac tctgatttga tttcagagta taaaaatgag attgaaacat gtgtaaacga
     2161 aataagaaaa ttaaattggg atattgtttc tgtgaaaaaa gaaatacaag ataaggcgaa
     2221 ggtagagctt gaaattgaag atttaaaaaa acaagtagaa aagctatctc ataagagtta
     2281 taaagatgtt tatgatgagt attcaaaaga gacagatatt tatagggaac tgaaacgtga
     2341 tgtggaggca cttaaggaaa ttcccaaaaa tctaactgat agtgttgaca aaattgactt
     2401 tggcaatggt ataaaagtta cagacgaaat tgatgaacac cgcggagaat tgattaagaa
     2461 tttagtgacc aatcgggcta agattcaaac aataattaat gaaatgtcag atgaaattga
     2521 tagttataga gcagagctga ataaatcaga ttggaaagtt aactataatg aggtttcaaa
     2581 gaggtatcaa agaggtatca aaaacttagt gaagagttat ctcaagatga attaaaaatg
     2641 ttacaaaacc ttgattcttt atatcaatct ttatcaaaaa ctgaagagcg attggaagaa
     2701 attattcaac aagaaataaa gcttaaagat taccaagttg aggttgactc agcaatgtca
     2761 agaatgaata aatcatatca aaatctctat tctgagagaa gtagttcctc gcgcgaaatt
     2821 ttttctgata ttacaggaat agaggctact attcaaccaa atagggattt caataattat
     2881 gttaaagagc tcagagcttg tattaataag gaggacactt ttgacagtga gtttggatct
     2941 cttattgata agctgacaaa aaattccatt actaatcaag atatatataa tgacatactt
     3001 gatataagag ttagtgggga aagtagtatt ttttcagata aaaaattaat caattctata
     3061 agaaaattga atgatgcaca agttcttgaa ttacaaaccc ttaagccaaa tgatttagta
     3121 gttatccgac ttgaactaaa tggaaaaaaa gttagtttat cgaatgctag tgctggtcaa
     3181 aagacatctg caattctttc tatgattttg gcgtatggaa attcaccact catattggat
     3241 cagcctgaag atgatttgga tagtcaatta attaataact taatcgtaag aagtatcatt
     3301 acaaaaaagg aaaacagaca aattttaatt gtaactcata atgcaaatat cccagttaat
     3361 ggtgattcag aatggttgat tagcatggga gattcaaaag aaatatcggc tgatcagtgc
     3421 gggtcggtag atgaacccaa tatcaagcca agaatatgta ctgtgatgga aggtggcgag
     3481 gatgctttta caaatagagc gaaacgctat ggttttaaac aaattgtaga ataacactag
     3541 agggtgagac atattattat gtccgccctt tttaggagga aaaatgaaaa aaataaaaag
     3601 ctataccagt atctgggcag ttgaaaaagt catttacgca atcaatgatt ttcagttgcc
     3661 ttttcctgtg acttttaacc aaatggcttg gttcgtttta tctttactgt ttgtcatcgt
     3721 atttgcccat gtgcctccac tatctatgat agaggaggtc tttttaaaat acttaggcat
     3781 accggtggct gtcacttggt ttatgtcgca aaagacgttt gatggcaaga aaccactggg
     3841 atttttacga tcctttatca gctatcactt gcgatttaag gtgacttttg caggaaagaa
     3901 agtcaaagaa cagaagaaac gatgggatga acccagtact cttgtaagga gtgtgaacta
     3961 tgtatccgat taagtatatt gaaaataatc tcgtctttaa ccaagaaggc gagtgttttg
     4021 cctactatga attagtgcct tacaattact cctttttgtc acccgaacag aaatttcaag
     4081 tgcatgataa ctttcgccaa ctaattgcgc aaaatcgtga aggcaagatc catgcgttac
     4141 aaattgccac agaaagtagt attcgcgcca cacaagaacg atcaaaaaaa gaaattaccg
     4201 gtagactcaa agaagtagcg aaacaacgaa ttgatataca gacagaggca ttagtatcca
     4261 tgattggcga tagtcagatt gattatcgct tttttattgg ctttaaacta attgcgacag
     4321 atgaagaagt caatctaaag agtctcaaga aatctttctt ttctgggctt caagaatttg
     4381 tctatggagt gaatcatcat ttgatgggcg attttgtttc cttatccaat gaagaaattc
     4441 gctgctattc taagcttgaa aaattaatgg aaagcaaatt ggctcgaaga tttaaagtca
     4501 ggcgagtcac accgagtgac ctgacgtatt tgattgaaca tatttatggc gaaaaaggga
     4561 taccgtttga agaatacgaa tttcagctac caaagaaaaa gctaaaatca gaaacactgg
     4621 tgaaacgtta tgacttatta cgtccaaatc gttgtttaat tgaagaaaaa ccaaggtgct
     4681 tacggatgga acatgagaat catgagtcgt acgtagcgta tttaacaatt aatacaattg
     4741 tgggggagat ggaatttcct tcctcagaac ttttctatta ccagcaacaa caatttacat
     4801 tcccaatcga cacaagtatg aatgtagaga ttgtgacgaa taaaaaggct ttagctaccg
     4861 ttcgtaataa gaaaaaagaa ctgaaagatt tagacaatca tgcttaccaa tctgacaatg
     4921 aaacgaattc caatgtctta gatgctttgg attccgtgga tgaattggaa accaccttgg
     4981 atcagtcaaa agaatctatg tacaaactga gttatgtggt tcgagtgagt gccgaatcag
     5041 tggatgaact aaagcgacgc tgtgatgaag tgctcgattt ttatgatgat accaatgtaa
     5101 aactagtccg gccctttggc gatatgatgg ggctacatga agaattctta ccctcaagta
     5161 aacgatatat gaacgactat attcagtatg ttacgtctga ttttttggcg gggcttggtt
     5221 ttggggctac tcagatgcta ggagaattag aagggattta ctttggctac aatgtggata
     5281 caggtcgtaa tgtttacctg aaaccggcat tggcttcaca aggagtcaag ggttcagtaa
     5341 ccaatgcgct ggccgccgct ttcctgggtt ctcttggtgg aggtaaatcc tttagtaaca
     5401 atctcttagt ctactatgct gttttgttcg gtggtcaagc tgtgattgtc gatccaaaag
     5461 gggagcgagg agggtggaaa gaaaccttgc cagaaattgc ggatgaaatc agtatcctca
     5521 acttgacgag taagtcagaa aatcaaggtc tgcttgatcc ttatgtgatt atgaagaaaa
     5581 agaaagactc ggaaagttta gcaattgata ttctgacttt tttaacagga atttcaagtc
     5641 gagacgggga gaagtttcct gtgttacgta aagccattcg aacggtgact caaagtgatc
     5701 aacgggggtt attacaagtt attaacgaat tgcgaaaaga cgggtcacca atcgcggaaa
     5761 atatcgccga tcatatcgag tcctttaccg attatgattt tgctcatttg cttttctcag
     5821 acggctcgat tacccaatcg attagtttag ataaacagct aaatatcatt caagtggcgg
     5881 atttggtttt accggatgca gaaacgactt ttgaagaata taccaccatg gaattgctta
     5941 gtgtttcgat gctaatcgtc atttccactt ttgccttgga ctttatccat agtaaccgag
     6001 aaatcttcaa aattgtcgat ttggatgagg cttggagttt tcttcaagtg gctcaaggaa
     6061 aaacgttatc gaataagctt gttcgtgctg gtcgggccat gaatgctggg gtctatttcg
     6121 tcactcaaaa tagcgacgat ttattagatg aacgtttaaa aaataatatc gggttgaagt
     6181 ttgcttttcg cagtaccgat attcatgaaa tcaagaaaac cttggaattc tttggtttgg
     6241 atcaggagga tcaaagcaat caaaaacgcc tgcgagattt ggaaaac
//
LOCUS       DAFBVQ010000099         6265 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.104, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000099 DAFBVQ010000000
VERSION     DAFBVQ010000099.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6265)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6265)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6265
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.104"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(95..667)
                     /locus_tag="LLC22_002646"
     CDS             complement(95..667)
                     /locus_tag="LLC22_002646"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300842.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5435855.1"
                     /translation="MTNKDQNKNYLEAIILELQNNSKRINSVELEQFSEKIVQAKHIF
                     LAGAGRSGIAMQAFTNRLMHLGFSVSLVGEISSPHSQPGDLLIICSGSGETGSLKNLA
                     AKANQSGVSIALVTMKKDSSIGQLADSVLVLPGITKDENQREEDTFSQPMGSSFEQLA
                     FLTFDSLVLSLMDKTGESSETMFARHADFE"
     gene            complement(674..1336)
                     /gene="rpe"
                     /locus_tag="LLC22_002647"
     CDS             complement(674..1336)
                     /gene="rpe"
                     /locus_tag="LLC22_002647"
                     /EC_number="5.1.3.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300841.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribulose-phosphate 3-epimerase"
                     /protein_id="HBK5435856.1"
                     /translation="MTIAPSLLNAPIAEVKELFEILKEKNVDYLHIDVMDGCFVPDMA
                     FGPSVIKDIRPLTDVVFDVHLMIDTPEKIVTRFVEAGADIVTFHIEATKHAMKVIQLV
                     KEAGAKVGITFNPATPVSFIEPVLSLVDQVLVMTINPGTENKHFIQETVVKIEQLDVI
                     RKQNDYTYDIEVDGKIDNQTIKVCSKAGADIFVSGGFIFNGKNTPQEQIDKLNQSLEE
                     VK"
     gene            complement(1352..1867)
                     /locus_tag="LLC22_002648"
     CDS             complement(1352..1867)
                     /locus_tag="LLC22_002648"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjbQ family protein"
                     /protein_id="HBK5435857.1"
                     /translation="MRFHHDTLTIETVSGRPSYHDIRKELLDTVDTAGIENGMLVISS
                     PHTTCSLFFEETMHDTNFFGDDYLHVDINNVMETIIPKMTSENQYNSPGPKHIDFGTR
                     LSDPNYPAEKWVMLNTDAHLRSSIYGTNSMTLIVQEGKLLLGEMGRVYFVDWDQLRER
                     TRTINLMIMGE"
     gene            complement(1869..2153)
                     /locus_tag="LLC22_002649"
     CDS             complement(1869..2153)
                     /locus_tag="LLC22_002649"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351191.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5435858.1"
                     /translation="MKKLLVICGAGHATSTIAVAKLSKWLEEEGLTDQVKIYQSKIAD
                     ELNKIDEYDAVVSTTIVPDVIKAKVTNGLGLLTGIGTDAIYADVKERLGV"
     gene            complement(2187..3515)
                     /locus_tag="LLC22_002650"
     CDS             complement(2187..3515)
                     /locus_tag="LLC22_002650"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS galactitol transporter subunit IIC"
                     /protein_id="HBK5435859.1"
                     /translation="MDIVLNAFEWFIGLGSNVFLPLIIFVIGILFGLKPGKAFVSGVT
                     VGIGSIGLGLVLSLLSDGLGTAIQQMGEQYGGGLNILDIGVGVGGPLAYSTSLGILMI
                     PISLILNFIFVVLGWTKTLNVDIWNFWFAIFLGMITQSVTGNFWFGLIGAIVAVILQW
                     FLADRTQKTVSEFFGYPGISITHMMGLSGVLFAKPVNWVFDRIPGFNKIDADAETLTK
                     RFGVLGDTVVIGLIIGIVVGIMAGYDVAGIGNLGIMTAAVMKIMPKMVAMFMEGLMPI
                     AEAAKEFTNKKLNGRQVNIGMDAALTVGHPTIMSTSLLLVPISLLLALILPGNKVLPF
                     GDLAFFAFAICLMIPYFKGNIVRSLVGCSLYVVTTLYMATWLAPIITDVFTLASFDVG
                     TAGLVTMLLCGLWPVGLFVLLASYFGVIGIGGLGVVLVGASIYMNKVKKA"
     gene            complement(3529..3984)
                     /locus_tag="LLC22_002651"
     CDS             complement(3529..3984)
                     /locus_tag="LLC22_002651"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5435860.1"
                     /translation="MYLDKELCLFQLEVKDQKELFQVMSEQLKNAGCVKDSFLEGITN
                     REQEFPTGLEVNQIGFAIPHTDSAHVNSSQICFASLKEPLVFSDMTDKSHEIPVRLVF
                     MLAMSQPHEQIDTLQNLVSLFQNEEKVNELLACTTKEAFIELVHSAGVY"
     gene            complement(3987..5933)
                     /locus_tag="LLC22_002652"
     CDS             complement(3987..5933)
                     /locus_tag="LLC22_002652"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341578.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIA"
                     /protein_id="HBK5435861.1"
                     /translation="MIERHVNLLKLLSRQEDFKPASFFSDKLAVSTKTIYQDIELLED
                     YVVNYQVTIERLPSLGIKLIGDRKNVEHLISSVENYLEKDIYSPEKRRVEIIKEVLFG
                     DKPVSLTHLSQSFMVSKTSLYNDLRIINKIIGSGEVKLQSSAEGISFTGNEQAIQRAI
                     KQLVFYYANDMESKTFFQVLNMLFDSKVISVIHDLLFNDYSELTEKVSDYYVRSLIST
                     LVIQCNRLLKGHHLTVEEEFLFNSIRYMETYIVANGLIEELKAKLNLPFYDADKEYLC
                     RQLFAHRVTNNLKTSNEEYAMSVHKLIERMSEIEKIDLTQNDRLYQSLLYHVPAMVLR
                     LKKGIKIQNPLLENIKSQYSELFSIVWYAMSILEEEFDVTLTDDEVSLILIHFQIAIE
                     DQSKANNIIIICQYGISSAQLIYNKVRRFLPAKDNVEISTLDKFHLAEIGEVDLIISS
                     LSFDAGGIPLVRVSPLVSKTDYMNIMEAYTKYLIEEPSRFIQNELIPKAVKVPTISKF
                     VQSSLVKTGVQVESKEECLDLMISELEANSLVTEEFRASIFSREKMGNTNLESGVALP
                     HANPSMVIESNIFIVALKNAINWGDRKVKLVIMVSLAEEDVSEIRGVYEELYQFIGQK
                     EMVDRLLQVHDSEKLLRIFQQKGE"
BASE COUNT         2060 a         1205 c          875 g         2125 t
ORIGIN      
        1 aattattaag ttatgtctaa tcaaataaaa aaaccattct catatttgct gaataattag
       61 catttagaga atggtttttt atctttaaaa tctactactc aaaatctgca tgtcgagcaa
      121 acatcgtttc tgagctttca cctgttttat ccattaaaga taacactaaa ctatcaaagg
      181 tgagaaatgc taattgttca aaacttgaac ccataggttg tgaaaaagta tcttcttctc
      241 gttgattttc atctttggta atacctggta atacaagaac agaatctgct aattgaccaa
      301 tcgacgagtc ttttttcatg gtaactaaag caatgcttac accactttga tttgctttgg
      361 ccgctaaatt ttttaaacta cctgtttcac ctgagccaga acagataatt aataaatctc
      421 caggttgcga atgtggtgaa ctaatttcac cgacaaggct gactgaaaaa cctaaatgca
      481 ttaagcgatt cgtaaatgct tgcatggcaa ttccagagcg tcctgcacca gctagaaaga
      541 tgtgtttagc ttgaacaatt ttctcactaa attgttctaa ctctacagaa ttaatacgtt
      601 ttgagttatt ttgtaattct aagataatcg cttctaaata gtttttattt tggtctttat
      661 tggtcatgat cttttacttc acttcctcta atgattgatt tagtttatca atttgttctt
      721 gcggggtatt tttcccattg aagatgaaac cgcctgatac aaaaatatcc gcccctgctt
      781 tagaacaaac tttaatcgtt tgattatcaa tcttgccatc tacttcaata tcatacgtat
      841 aatcattttg tttgcgtatt acatctaact gttcgatttt aactactgtc tcttgaataa
      901 aatgcttatt ctctgttcct ggattgattg tcattactaa tacttgatcg actaaagata
      961 atactggttc aataaaactg actggtgttg caggattaaa agtaatccct acttttgctc
     1021 ctgcttcctt gactaactga atgaccttca ttgcgtgttt ggtagcttca atgtggaagg
     1081 taacaatatc tgctcctgct tctacaaatc ttgtgacaat tttttctggt gtatcaatca
     1141 tcaaatgaac atcaaacaca acgtctgtta gtggacgaat atctttaata acacttggtc
     1201 caaaagccat atctggtaca aaacagccat ccattacatc aatatgcaaa taatcaacat
     1261 tcttttcttt taagatttca aataactctt taacttctgc gataggtgca tttaacaatg
     1321 atggagcaat tgtcattctc tattcccccg tttattctcc cataatcatg agattgattg
     1381 ttctagttcg ctctcttagt tgatcccaat cgacaaaata gacacggccc atttctccta
     1441 ataaaagttt accttcttga acaattaaag tcattgagtt ggttccataa atagatgaac
     1501 gtaaatgtgc atcggtattt agcatgaccc atttttctgc agggtaattg ggatcagata
     1561 atcttgttcc aaaatcaatg tgttttggcc ccggactgtt gtattgattt tcactcgtca
     1621 tttttggaat aatcgtttcc attacattgt tgatgtctac atgtaaataa tcatcaccaa
     1681 aaaagtttgt gtcatgcatc gtttcttcaa aaaagagtga gcaagttgta tgcgggctcg
     1741 aaattactaa cattccattc tcaatacctg ctgtatcaac tgtatctaaa agttcttttc
     1801 gaatatcatg atacgaagga cgccctgaaa ctgtttcaat agtcaaagtg tcatgatgaa
     1861 aacgcatatt aaacacctaa tctttctttt acatctgcat aaatggcatc tgtaccaata
     1921 cctgttaata agcccaagcc attcgttact ttagctttaa ttacatcagg gacaattgtt
     1981 gtacttacta cagcatcata ttcatcaatt ttatttagct catcagcaat tttagattga
     2041 taaattttca cttgatctgt taatccttct tcttccaacc attttgataa ttttgctact
     2101 gcaattgtag aagtagcatg acctgctcca caaataacta ataatttttt catattgatc
     2161 tcttctttct tattttaatt ttatgattaa gctttcttca ctttgttcat gtagatagaa
     2221 gcacctacta aaacaactcc taatccacct attccaatta caccaaagta agatgctaat
     2281 aaaacaaaca accctactgg ccataatcca cataacaaca tagttactaa tcctgctgtc
     2341 cccacatcga aacttgctaa tgtaaacaca tcagtgataa ttggtgccaa ccatgttgcc
     2401 atatataatg ttgtaacaac atacaacgaa catcctacta atgatctcac aatatttcct
     2461 ttaaaataag gaatcattaa acagatggcg aaagcaaaga atgctaaatc tccaaaaggt
     2521 aatactttat ttcctggaag aattagtgct agcaataatg agattggtac aagcaataga
     2581 gaagttgaca taatagttgg atgacccaca gttaacgctg catccattcc aatgtttact
     2641 tggcgaccat ttaacttttt attcgtaaat tctttcgccg cttctgcaat tggcattaaa
     2701 ccttccataa acattgctac cattttaggc ataatcttca tcactgccgc agtcataatt
     2761 cctaagtttc caattcctgc tacgtcatag cctgccataa tacccactac aataccgata
     2821 attaggccaa taacaactgt gtcacctaaa acaccgaaac gttttgttaa tgtttctgca
     2881 tctgcatcta ttttattaaa tccaggaata cgatcaaaaa cccaatttac tggtttggca
     2941 aatagtactc ctgataatcc catcatatgt gtgatagaga ttcctggata gccgaaaaat
     3001 tcgctaacag ttttttgtgt acgatctgct aagaaccatt gtaaaattac tgcgacaatc
     3061 gcgccaatta agccaaacca aaagtttccc gtaacagatt gagtaatcat acctaggaaa
     3121 attgcgaacc aaaagttcca aatatcaaca ttcaatgttt ttgtccaacc caaaaccaca
     3181 aatatgaagt taagaattaa tgaaattgga atcattaaaa ttcccaatga tgtagagtaa
     3241 gccaaaggtc caccaacacc tacgccaata tctaggatat tcaggccacc accgtattgt
     3301 tcccccattt gttgaattgc tgttcctaaa ccatctgata ataaacttaa aactaatcct
     3361 aaaccaatag aaccgatacc aacagtaacg ccggaaacaa atgctttacc aggttttaat
     3421 ccaaataata tcccgattac aaaaataatc agtggtaaaa agacgtttga ccctaatcca
     3481 ataaaccatt caaaggcatt taatacaata tccatctctc tattcctcct aataaactcc
     3541 tgcagaatgt actaactcaa taaatgcttc tttcgtggta catgcaagta attcatttac
     3601 tttttcttca ttttgaaata ggctaactaa gttttgtagt gtatcaattt gttcatgagg
     3661 ttgtgacatt gccaacataa agactaaacg tacaggtatt tcatgagatt tatctgtcat
     3721 atctgaaaat accagtggtt cctttaatga ggcaaaacag atttgagagc tatttacatg
     3781 tgcggaatct gtatgtggga tagcaaaccc aatttgattt acttctaatc cagttggaaa
     3841 ttcttgttca cggttggtga taccttctaa gaaactatct ttcacgcaac cagcgttttt
     3901 taattgttca gacattactt gaaacaattc tttttgatct ttcacttcta attgaaataa
     3961 acataattct ttatctagat acatttttat tctccttttt gttgaaaaat tcttagtaat
     4021 ttttcgctat catgaacttg taacaagcga tcgaccattt ctttttgccc aataaattgg
     4081 taaagttctt catatactcc tctaatctca gatacatctt cttcagctaa actaaccata
     4141 atgactaatt tgacttttcg atcgccccaa ttaatcgcat tttttaatgc tacaataaaa
     4201 atgttggatt caatgaccat tgatggattc gcatgcggta aagcaacacc actttctaaa
     4261 ttagtattcc ccattttctc tctagagaag atagaagcac gaaactcttc agtaactaat
     4321 gaattggctt ctagttcgga aatcatcaaa tccaaacatt cttctttgct ttccacctgt
     4381 actcctgttt ttactaaaga tgattgaaca aatttagata tggtgggaac tttaaccgct
     4441 ttaggaatca gttcattttg aataaatcgc gaaggttctt ctattaaata tttagtataa
     4501 gcttccataa tattcatata atctgtttta cttaccaatg gagataccct tactaagggt
     4561 ataccacctg catcaaagga aagagaggaa ataatcaaat caacttcccc aatttcagct
     4621 aaatgaaact tatctaaagt tgatatttct acattatctt ttgctggtaa aaaccgtcga
     4681 actttattgt aaattaattg cgcagaagaa ataccgtatt ggcaaataat gatgatatta
     4741 tttgctttgg actgatcttc aatagcaatc tgaaaatgaa tcaaaattaa ggaaacttca
     4801 tcgtccgtta aagtcacatc aaattcttct tcaaggatgg acatggcgta ccatactatg
     4861 ctaaagagtt ctgaatattg agatttgata ttttctaata acggattttg aattttaata
     4921 ccttttttta aacgaaggac cattgctggc acatgataca ataaggattg atataatcga
     4981 tcattttgag tcaaatcaat tttttcaatc tcactcattc tttcaatcaa tttatgaacg
     5041 ctcatagcgt actcttcatt gctggttttt aaattatttg tcacacgatg tgcaaatagt
     5101 tgacgacata gatattcttt atctgcgtca taaaatggaa gattcaattt tgccttcaat
     5161 tcttcaatta aaccatttgc cacaatgtac gtttccatat agcgaatgct attgaagagg
     5221 aattcttctt caacagttaa atgatgacct ttcagtaaac ggttacattg gataactaaa
     5281 gtagaaatca atgaccgaac atagtaatca gaaacctttt cagtcagttc actgtaatca
     5341 ttgaatagca aatcatgaat gacactaata acttttgaat caaacaacat atttaaaact
     5401 tgaaaaaatg tttttgattc catgtcattc gcataataga atacaagttg cttgattgct
     5461 cgttgaattg cttgttcatt accagtaaaa ctaattcctt ctgcagatga ctgcaactta
     5521 acttctccac tgccaataat tttattgata attctcaggt cattgtataa cgatgtttta
     5581 ctaaccataa aactttgaga caaatgagtt aaagaaacag gcttatcacc aaacaaaact
     5641 tctttaatga tctcgacacg tcttttttct ggagaataaa tatctttttc aagataattt
     5701 tctaccgatg aaatcaaatg ttcaacgttt ttcctatcac ctatgagttt gatacccaaa
     5761 gaaggtaatc gctcaattgt tacttggtaa ttaactacat aatcttccaa caattcaata
     5821 tcttgataaa tggtcttggt cgacactgcc aatttatcac taaaaaaaga agcgggttta
     5881 aagtcttctt gtcgacttaa taattttaat aaatttacat gtctttcaat caaacttgtt
     5941 cacctcttaa cgctagcatt tgttacctct tttcattatt tattctagca ctggaacccc
     6001 cttccctcaa ttacatctat gtcaataata cttgtggaag tttgttgtaa aggaaatcca
     6061 aataatctta aaaaatgaga aacaaaaaag gagaaatcct taaaagagct aagatattcc
     6121 aatagaaaat actccttatt atggaagtaa tatgaaatat tacaattgaa aaataaaaac
     6181 aatataatgg cgtcactaaa attcgtattt ttttattata atataactta attacaaatg
     6241 ctcatctatg aacaattgag tccta
//
LOCUS       DAFBVQ010000100         6259 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.105, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000100 DAFBVQ010000000
VERSION     DAFBVQ010000100.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6259)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6259)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6259
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.105"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            516..602
                     /locus_tag="LLC22_002653"
     CDS             516..602
                     /locus_tag="LLC22_002653"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000493114.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type I toxin-antitoxin system Fst family toxin"
                     /protein_id="HBK5435862.1"
                     /translation="MFELFICPLLIEVCVSLFSYWLNNRNKK"
     gene            complement(723..1412)
                     /locus_tag="LLC22_002654"
     CDS             complement(723..1412)
                     /locus_tag="LLC22_002654"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298772.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435863.1"
                     /translation="MAFYLPYLLIFASILGIIWLSYKAYQTRYSLKGSKIRFKRFLLP
                     GVIFTLSIVLSGLFGVLEGNKRISRSILLGDITQKYEAACDKKKKEQVLTQKMEEFTT
                     CYEEMNDIFVNQEKRLTDKNMEKLTRLYQNLPEKQQKEVQDNYERTKKDVQYFKDTQT
                     EEACYNLFSDTIPFSTSEQERKERQQSVTYERYKALLQQATNIQNPTKKETALNYLKS
                     VKEWLDQQQQN"
     gene            complement(1419..1697)
                     /locus_tag="LLC22_002655"
     CDS             complement(1419..1697)
                     /locus_tag="LLC22_002655"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002354385.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435864.1"
                     /translation="MKEEQTTNKNYRSKTLQDIENEIKKQRAFLAPYTKERIQTTIDS
                     QVKKFHHALLNQRNKEQKKVIMQRSMDILAPLCCLIMTLLAFWLVWGE"
     gene            complement(1657..2571)
                     /locus_tag="LLC22_002656"
     CDS             complement(1657..2571)
                     /locus_tag="LLC22_002656"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340563.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="relaxase/mobilization nuclease domain-containing
                     protein"
                     /protein_id="HBK5435865.1"
                     /translation="MATVKVSRTTSCSRAINYAEPRATVKTGINCDIDYAKSEMKQIR
                     MLYGKDDRVQAHLLIQSFRPGEITAEKANQLGAEYAKKIAPDHQIAIYTHTDKDHIHN
                     HIVINSVNLETGNKFQAHGQAFLNKCYDLNDEICLEHDLTITERGKKPEKRTMSEIKL
                     KEKNEPVWKDEIRFAIDQTMKNKKTRTYNQFCDSLKTFGIHCLNRGKNFTYELIHKKK
                     KVRSNKLGKDYEKETILHELDRRERAYNQQRTNELRRARASIRETAKEVRREQRTLTT
                     EQPEIRPTRRNHDQHVERGADYQQELSF"
     gene            complement(2553..2933)
                     /locus_tag="LLC22_002657"
     CDS             complement(2553..2933)
                     /locus_tag="LLC22_002657"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348702.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MobC family plasmid mobilization relaxosome
                     protein"
                     /protein_id="HBK5435866.1"
                     /translation="MSEQNQYLASNHSKKYTYRSEPKQISFRVSESEFAKLKQSAEAL
                     QMSVPAFVKAKAQNARLVTPKVAPDIAQAIARDLAKAGGNINQIAKWCNTHQHDVDPG
                     DAQRLSENLKIMQKELQKIWQQLK"
     gene            complement(3383..3670)
                     /locus_tag="LLC22_002658"
     CDS             complement(3383..3670)
                     /locus_tag="LLC22_002658"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin immunity protein"
                     /protein_id="HBK5435867.1"
                     /translation="MDFTKEEKLLNAISKVYNEATIDDYPDLKEKLFLYSKEISEGKS
                     VGEVSMKLSSFLGRYILKHKFGLPKSLIELQEIVSKESQVYRGWASIGIWS"
     gene            complement(3690..3914)
                     /locus_tag="LLC22_002659"
     CDS             complement(3690..3914)
                     /locus_tag="LLC22_002659"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363584.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriocin hiracin-JM79"
                     /protein_id="HBK5435868.1"
                     /translation="MKKKVLKHCVILGILGTCLAGIGTGIKVDAATYYGNGLYCNKEK
                     CWVDWNQAKGEIGKIIVNGWVNHGPWAPRR"
     gene            complement(4369..4539)
                     /locus_tag="LLC22_002660"
     CDS             complement(4369..4539)
                     /locus_tag="LLC22_002660"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002322958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435869.1"
                     /translation="MTKKHLLFGSILLGILSFSPMLLSVANKGNKKGELKLNPNYYNS
                     QNEEVFVEKLDK"
     gene            complement(4554..5087)
                     /locus_tag="LLC22_002661"
     CDS             complement(4554..5087)
                     /locus_tag="LLC22_002661"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002292473.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF536 domain-containing protein"
                     /protein_id="HBK5435870.1"
                     /translation="MQPQETFTIKELSDLFKMSRQAISKHIQKLDSSMIAKNERGYKV
                     VLRSGVLQLARNLDNQRLLDKLHKHEQNNDKNAYIPNKNVVANKLLDQLREENEFLRE
                     QLALKEQNNSHIQKLLDQQQQLTLQANQQIEKLQEQLQLTYTEESSENSSTTLSEATE
                     TMDEQTKNWKKWWQLWK"
     gene            complement(5108..6052)
                     /locus_tag="LLC22_002662"
     CDS             complement(5108..6052)
                     /locus_tag="LLC22_002662"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RepB family plasmid replication initiator
                     protein"
                     /protein_id="HBK5435871.1"
                     /translation="MANEIVKYHHELNTIPLRKFTPVEMNLFFSIVSRMREKGDKTVR
                     FTFDQLKDLSNYKATANVRFVEDLKATYEKILSLRFGRRSESGLSYDMFVMFTEFKIN
                     GDVENPYVDIRIYEKALPLLNNLDEWVRYSLQQFNELQSGYAKTMFRLLKQYRTKGFA
                     YFSKEDFLELLDIPKSYKQPDIDKRVIKPIRQELTAIFKGLTIKKKYGKGRGKPVIGY
                     QFTFKPEIKKADDFNKHAPTKEDQNKALALADKQKEYEEPATTINEKIKQKKRELELL
                     QQIKQLEKEKKALEKQTESALSEKEKKSLLSDLDNLFQ"
BASE COUNT         1662 a         1167 c         1058 g         2372 t
ORIGIN      
        1 tgtccttcat aaacagacaa aatgtccttc ataacattct gtatccattg gtagagtaag
       61 gacacagctt acggtaaaga ggtttaaaaa gaggtttaaa aagagatata aaaagagggg
      121 ggctaatttt cccgcctaaa aaccacttct tttttcttta aacaggttcg cgcatttttc
      181 aaaactgcca atccaaaacc ttgcttccta cggtcgccaa aaaggtgtga tcgctacgct
      241 ctcacattgt actgcgcagt cgcctaaagg ctcctttgct aaaaacatgt tggtaaagag
      301 gcctttgagc ggttctgaat gcttatctaa gccgttttaa gacagtcttg gataaaaatc
      361 cttatctagc tttaaagcgc cttacaggcg gtcagggcaa gccctaacaa ccctaaaata
      421 agcgatactt aaaaacacca cacaagttta attttttaag atataataac ttgtcgccta
      481 tccgacagtc ttgcgactgg aaggaggtgt atctaatgtt tgaattgttc atttgccccc
      541 ttcttataga agtttgtgtc tctttattca gttattggtt gaataaccga aacaagaagt
      601 aaaatcaata aaggcgacat caacctgaaa aaaagcccca gagaatccga cctctctggg
      661 gctttcgtgt atctaatgtt tgatcatttg catgtttagt ttaacatgat tgccgatcaa
      721 attcaatttt gctgttgctg atctaaccat tccttgacac tttttagata atttaatgcc
      781 gtttcttttt tcgttggatt ttgtatgttc gttgcttgct gaagcagtgc tttataacgt
      841 tcgtaggtaa ctgattgttg ccgttctttt cgttcctgtt cactagttga aaaagggatt
      901 gtatcactga ataaattata acaagcttct tctgtctgcg tatctttaaa atattgcacg
      961 tcttttttgg ttcgctcata gttgtcttga acctcttttt gctgtttttc tggcaagttt
     1021 tgataaagac gagtgagttt ttccatgttt ttatccgtca aacgtttttc ttgattcaca
     1081 aaaatatcgt tcatttcctc ataacaagtg gtaaactctt ccattttttg tgttaacact
     1141 tgctcctttt tctttttatc acatgctgct tcatactttt gagtgatatc ccctaataaa
     1201 atacttcttg aaatacgttt atttccctct aaaacgccga ataaaccact taaaacgatt
     1261 gataatgtaa atataacccc tggcaataaa aacctcttaa atcgaatttt agagcctttt
     1321 aatgaatatc ttgtttgata agccttatag ctaagccaaa taattcctaa aatactggca
     1381 aaaatgagta gatagggtaa atagaatgcc atttctattt attctcccca taccagccaa
     1441 aaggctaaca gtgtcatgat taagcaacat aagggggcaa gaatatccat tgatcgctgc
     1501 ataattactt ttttctgttc tttatttcgc tggtttaata gcgcatggtg gaattttttg
     1561 acttgtgaat caattgtagt ttgtattctt tctttggtat aaggtgcaag aaaagcacgt
     1621 tgtttcttta tttcattttc tatgtcttgt aacgttttag aacgataatt cttgttggta
     1681 gtctgctcct ctttcaacgt gttggtcatg gtttcttcga gtcggtctaa tttccggttg
     1741 ttcagtcgta agagttcgtt gttctcttcg tacttctttt gcagtttcgc gaatgctagc
     1801 tcgagctctt cgtagctcgt tggttcgttg ttgattgtag gctcgttctc gtctgtccag
     1861 ctcatgtaaa atcgtctcct tttcgtaatc ctttcctagt ttgttggatc gtactttttt
     1921 ctttttgtgg atcaattcgt aagtaaaatt tttcccacga ttcaagcaat gaatgccgaa
     1981 tgttttaaga gaatcacaaa attggttata cgttcgagtt tttttgtttt tcattgtttg
     2041 atcaatcgca aaccgaattt cgtctttcca aacaggttca tttttttctt ttaatttgat
     2101 ttcagacatg gttcgttttt cgggtttctt ccctcgttca gtgattgtta agtcatgttc
     2161 aagacaaatc tcgtcattta ggtcataaca tttgtttaaa aatgcttgac catgggcttg
     2221 aaatttgttc ccagtttcca gattgacgga gttaatgaca atgtggttat gaatatggtc
     2281 tttgtctgta tgtgtgtaaa tcgcgatttg gtggtcaggg gctatttttt tcgcatactc
     2341 tgcccctagt tgattggctt tttcagcggt aatttctcct ggtcgaaaag actggatcaa
     2401 taagtgtgct tgtacacgat cgtcttttcc atacagcatg cgaatttgtt tcatttcgct
     2461 tttggcataa tcaatgtcac agtttatccc tgttttgacg gttgctcgtg gttcggcgta
     2521 attgatcgct cggctacaag aagtggttcg gcttacttta actgttgcca tatcttttgt
     2581 agctcctttt gcatgatttt taggttttcg gataagcgtt gggcgtcgcc aggatcaacg
     2641 tcgtgttggt gtgtgttgca ccacttggca atttgattga tattcccgcc agctttggct
     2701 aaatcgcgcg cgattgcctg agcaatgtct ggcgccactt tcggtgtcac cagacgcgcg
     2761 ttttgtgcct tggctttcac gaaagccggc acactcattt gcaaagcttc agctgactgc
     2821 ttcagctttg caaattcgga ttcgctcact cgaaaactga tttgttttgg ctcggatcga
     2881 taggtatatt ttttagaatg attgctagcc aaatattgat tttgttcgct cataagtccc
     2941 accctttcag tacgtcctac ggacgtatcg ttcgcaatac cattgtacct aaaaaggtac
     3001 aataagtaaa gctcactaaa gctcactaaa gggcttggca agctctatat ttgctagcca
     3061 aatacctacg tatttggtgc aaataaccgc ttgtcaaagg ggcgcaagct cccccttgaa
     3121 tccccctccc ccccactctc cacaatacaa aaaagactag caaatgctag ccactttttg
     3181 taaagtttcg cttgtttcac cttcggtgaa attgttgcaa atcaataatt aggtagagct
     3241 acattttttt cgttgttcaa agattcttat gccatttact attaataaat ctataaatat
     3301 gataattttt cggctctata atttatggga ctgatgaatc agaattgatt cttcagtccc
     3361 attttcattt tattccaaag aattaactcc aaataccaat agaagcccat cctctatata
     3421 cttgagattc cttactaaca atttcttgta attctattaa agatttaggt aatccaaatt
     3481 tatgttttaa aatatatctt ccaagaaaac tacttaattt catactaact tcaccaacac
     3541 tttttccctc actgatttct ttagaataaa gaaagagctt ttcttttaag tcaggatagt
     3601 catctatagt tgcttcattg tatactttac taattgcatt taaaagtttt tcttctttag
     3661 taaaatccat tataataacc tccctaccac taccttctag gtgcccatgg accatgatta
     3721 acccaaccat taacaataat ttttccaatt tctcctttag cttgattcca atctacccaa
     3781 catttttctt tgttacaata aagaccattt ccatagtaag tagctgcatc aacttttatt
     3841 cctgtaccga tgccagctag acaagttcct aatattccta gaataacaca atgttttaat
     3901 actttctttt tcatgattgt ttttcctttt cgttttttta aaattgcttg ttatattaaa
     3961 taatcttagt aattttatta tataacattt tattatataa caatgattaa cgtcataaaa
     4021 agtagttttg aattcataat cgtttaaata aaattataag atcagttatt taaacagcta
     4081 gtagacataa tgtgtatact accaagtaac gcctgtacca agggatccag gcgctgattt
     4141 tgtgaatttt tattggtcta ggttaaaagc tctttttaag gcttggtttt ctgcggttgt
     4201 ttctttctaa ttctttgtga atattgatcg gtcatttttt aaatacttgt tatttttgtt
     4261 tgtgtttgtt atgcttttta catatctcat attcatttat tattcttttc taaggttaat
     4321 aataggataa tctctttcag aaagactgct cgtacgagca gtcttttctt atttatcaag
     4381 tttttctaca aatacttcct cattttgact gttgtagtaa ttaggattga gttttagttc
     4441 ccctttttta tttcctttgt tggccactga taataacatt gggctaaagc ttaatattcc
     4501 tagtaggata gaaccgaata gcaagtgttt ttttgtcata agtatttcct tcttcatttc
     4561 catagctgcc accatttttt ccaattcttt gtttgttcgt ccattgtttc tgttgcttca
     4621 gaaagagtcg ttgaactatt ctctgaagac tcttccgtat aagtcaactg cagttgctcc
     4681 tgaagttttt cgatttgttg gttggcttgc agggtgagtt gttgttgctg gtcgagtagt
     4741 ttttgtatat gagaattatt ttgctctttg agggcaagtt gttctcgtaa aaattcattt
     4801 tcttcacgca actgatctag caacttgttt gcaaccacgt ttttgtttgg tatataagca
     4861 tttttatcgt tgttttgttc atgtttatgc aacttatcta gcaacctttg attgtctaag
     4921 ttgcgagcaa gttgcaatac tccagaacgc aatacaacct tataaccacg ctcattttta
     4981 gctatcatgg aagaatctaa tttttggata tgtttcgata ttgcttgcct actcatctta
     5041 aaaagatctg acaattcctt tattgtaaag gtttcttgtg gttgcatact ggttgcctcc
     5101 taggttgcta ctggaataaa ttatctaaat cagataataa actttttttc tctttttccg
     5161 aaagtgcgga ctctgtttgt ttttcaagag cttttttctc tttttctagt tgtttgattt
     5221 gttggaggag ttcaagttct cgtttcttct gtttgatttt ttcgttaatt gttgtagcgg
     5281 gttcttcgta ttctttttgt ttatcagcta aagccaatgc tttattttgg tcttctttgg
     5341 ttggtgcatg tttgttaaag tcgtctgctt ttttgatctc aggtttgaac gtaaattgat
     5401 agccaataac aggttttccc cgtccttttc cgtatttctt tttgattgtt agtcctttga
     5461 agattgcagt tagttcttga cgtataggtt ttataactcg tttatctata tcaggttgct
     5521 tataactttt aggaatatct aataattcaa gaaagtcttc tttggagaaa tatgcgaaac
     5581 ctttggttct gtattgcttt aacagacgaa acatagtctt tgcatagcca ctttgtagct
     5641 cgttgaattg ttgtaaagaa tagcgtaccc actcgtctaa attatttaac aaaggcagtg
     5701 ctttttcgta aattcgtata tctacgtaag gattttctac gtccccgttg attttaaatt
     5761 ctgtaaacat tacaaacata tcgtaagaaa gcccagactc acttctacga ccaaagcgta
     5821 aagataagat tttttcataa gttgctttta aatcttctac aaatcgtaca tttgcagttg
     5881 ctttgtagtt acttaaatct tttagttggt caaacgtaaa acgaactgtc ttatcccctt
     5941 tttcacgcat tctagacacg atggaaaaaa acaaattcat ttcaaccggt gtaaattttc
     6001 ttaaaggaat tgtatttaat tcatggtggt attttacaat ctcattagcc atataatcac
     6061 ctcaatccaa ttatgaatga cattttttaa atgtcaagac attcatattt gacgttcaaa
     6121 cagacaaaat gtccttcata aacagacaaa atgtccttca taaacagaca aaatgtcctt
     6181 cataaacaga caaaatgtcc ttcataacat tctgtatcca ttggtagagt aaggacacag
     6241 cttacggtaa agaggttta
//
LOCUS       DAFBVQ010000101         6203 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.106, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000101 DAFBVQ010000000
VERSION     DAFBVQ010000101.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6203)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6203)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6203
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.106"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            192..710
                     /locus_tag="LLC22_002663"
     CDS             192..710
                     /locus_tag="LLC22_002663"
                     /EC_number="3.4.21.89"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294028.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="signal peptidase I"
                     /protein_id="HBK5435872.1"
                     /translation="MPDYKKITFISSITLIIFLILILLVVLVPRIFGLTPYIIEDKEM
                     SPYYAQGNLIYVRPKNTNEILVGDIITYYENSGKKISTRRVIAVENNHEDFYTKADTK
                     TYIEPGVVKKRNIIGSPIFQIPYIGLVLSKTAFAWIQGLFFTIAFCLTGITAWNTFVE
                     LKKKRRRTQKFL"
     gene            838..1521
                     /locus_tag="LLC22_002664"
     CDS             838..1521
                     /locus_tag="LLC22_002664"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343050.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="O-methyltransferase"
                     /protein_id="HBK5435873.1"
                     /translation="MRNEMMHRPVVKEELLDFMRTQQKKLPGELGKLEEEAHVAEVPV
                     IPHETVVFLKFLLGQLQPERILEIGAAIGFSSSVMATTIGENAHVTTIDRFDVMIEKA
                     KKNYERLGLTDKVTLLEGQAADILPELSGPYDFIFMDSAKSKYIEFLPECLRLLRKGG
                     VLMVDDIFQGGTILLPDEEIPRGKRAIHRKLNEFLRVVMDHPDLTSTILPLGDGVILM
                     TKESETIEL"
     gene            1830..1903
                     /locus_tag="LLC22_002665"
     tRNA            1830..1903
                     /locus_tag="LLC22_002665"
                     /product="tRNA-Arg"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:1864..1866,aa:Arg,seq:tct)
     gene            2062..2421
                     /locus_tag="LLC22_002666"
     CDS             2062..2421
                     /locus_tag="LLC22_002666"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016922519.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1304 family protein"
                     /protein_id="HBK5435874.1"
                     /translation="MTILSRILVTLVAIEFFYIMYIETVRTDSDTTSRVFKMSKEELS
                     RKSVQTLFKNQGVYNGLLGVGLLYGAYLSSASKEITSMLLISIFFVALYGSLTSDRWI
                     LLKQGGLALLALLSIFL"
     gene            2544..4175
                     /locus_tag="LLC22_002667"
     CDS             2544..4175
                     /locus_tag="LLC22_002667"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SulP family inorganic anion transporter"
                     /protein_id="HBK5435875.1"
                     /translation="MFKNYVSSLKKEFSGYDLSRFQKDLLAGITVAAVALPLALAFGV
                     SSGADAAAGLITAIIAGIVIGGLSGGFYQISGPTGAMAAILMSIAATKGMQGVLLATF
                     LAGLFLLAAGLFRLGTLTSFIPAPVITGFTSGIAIIIALGQIDNLFGVHSEGTNVIEK
                     LSSYQTIGFPINTASLIMGGLVILGMFIYPKKWAKRMPSSLLAIILATAVMLLFHLPV
                     ATVGKIPQTLISSNRLNMGDFSFSALQQVAVPAISIALLGMIESLLCGASAGRMANKP
                     LDSNQELMAQGIGNLLLPFFGGIPATAAIARTSVAIKSGAQTRLAGMIHAVVLLLSML
                     VFAPVMSQIPMPALAGVLIVTAWRMNEWETIKELFTNKYWSAVLLFILTMICTVIFDL
                     SIAIVIGVIGGCVFFVVKSAAITISLETIDWQRMGLPETEKLNNWTVVYISGPLFFMS
                     SEKLKNKLEELNHHDGVIFSMRGVPSIDLTARAVFDEFQEKAEQRGQTIIYTSLQPEV
                     EKQLSHLWEHTFTHQHQTVAHALTALHAKYTAISH"
     gene            complement(4237..4878)
                     /locus_tag="LLC22_002668"
     CDS             complement(4237..4878)
                     /locus_tag="LLC22_002668"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uracil-DNA glycosylase"
                     /protein_id="HBK5435876.1"
                     /translation="MEYPKELIQEASLRMNGRPVEGFIAGQGPLHPKLMLVGEAPGKT
                     EIDTHVPFSGQAGKELMQALSSTGLTREEVYITSAVRSRPYRVTHRINKRTQQSETVY
                     PNRTPTRSEVFAHAPILDYELMKVQPKLIATLGNIGLQRLLGKEYTVTKNHGQLYTGP
                     VLQLTEQKDAYEWSEKNYRILPLFHPAAIFYNRSLVPVIHQDWQVLASLLQQY"
     misc_feature    5064..5140
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00559"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="ribosomal protein L21 leader region; Derived by
                     automated computational analysis using gene prediction
                     method: cmsearch."
                     /db_xref="RFAM:RF00559"
     gene            5160..5468
                     /gene="rplU"
                     /locus_tag="LLC22_002669"
     CDS             5160..5468
                     /gene="rplU"
                     /locus_tag="LLC22_002669"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002355866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L21"
                     /protein_id="HBK5435877.1"
                     /translation="MYAIIKTGGKQVKVEVGQAIYVEKLDVEAGEKVVFDEVILVGGE
                     STKVGAPTVAGATVEGTVEKHGKQKKVVTFKYKPKKHSHRKQGHRQPYTKVVIDAINA
                     "
     gene            5495..5839
                     /locus_tag="LLC22_002670"
     CDS             5495..5839
                     /locus_tag="LLC22_002670"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ribosomal-processing cysteine protease Prp"
                     /protein_id="HBK5435878.1"
                     /translation="MIKGTFKRNDAGQIVSFTLTGHADAGPYGSDIVCAGVSALAIST
                     VNGIASLAGFEPIVEMNEEEGGYLYTEVTSGMTQEQNNIAEILLENLLLGLQSIEAEN
                     SEYIQIKTINDK"
     gene            5852..6145
                     /gene="rpmA"
                     /locus_tag="LLC22_002671"
     CDS             5852..6145
                     /gene="rpmA"
                     /locus_tag="LLC22_002671"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289452.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L27"
                     /protein_id="HBK5435879.1"
                     /translation="MLLSMNLQLFAHKKGGGSTSNGRDSESKRLGAKRADGQTVTGGS
                     ILYRQRGTKIYPGVNVGIGGDDTLFAKVDGVVRFERKGRNKKQVSVYPVAQEA"
BASE COUNT         1951 a         1024 c         1313 g         1915 t
ORIGIN      
        1 cttgtaatgt tagggtaaac gttttttaaa ctaacgtcaa ttatttataa taaaaaatga
       61 gataaagatg aggaaataga attagaaaca tataattatt aaagggaaac atttttacag
      121 ctataatttg aaaaaaattt atcgttatta tatgattaag aaggattgaa taaagaaaga
      181 agttgaaaac gatacctgat tacaaaaaaa taacttttat aagttctata acgttgatta
      241 tatttttaat tcttattctt ctcgtcgtct tggttccccg aatttttggt ttgactcctt
      301 atattattga ggacaaagaa atgagtccat attatgcaca aggaaatctg atatatgtac
      361 gaccgaaaaa tacaaatgag attttagtcg gagatattat tacatattat gaaaattcag
      421 gaaaaaaaat ctcgacgcgt cgcgtaatag ccgttgaaaa caaccacgaa gatttttata
      481 caaaagctga tacaaagact tatattgagc ctggagtagt aaaaaagaga aatattatcg
      541 gtagtcccat ctttcagatt ccatatattg gactagtcct ttcaaaaacg gcatttgcat
      601 ggattcaggg gttattcttt acgattgctt tttgcctaac aggaatcaca gcatggaata
      661 cctttgtaga gttgaaaaag aagcggagac gaacacagaa atttttgtaa gaatgttaaa
      721 aacataaatg tattccagag atccaacgac tcttctgaac atgaaacacg agaaaacact
      781 catgcagctt gtagatttag tcagttgttc gtataatgtg tgaagaggag gagtagtatg
      841 cgcaatgaaa tgatgcatcg tcctgtagtc aaagaagaac tattggattt tatgcgtacc
      901 cagcaaaaaa aattaccggg tgagctaggc aaactggaag aagaagctca tgtagcagaa
      961 gtaccagtta ttccccatga aacagttgta tttttgaaat ttttacttgg acagcttcag
     1021 cctgaacgaa tcttggagat cggagcagct atcggttttt catcaagtgt catggccacg
     1081 acaatcggag aaaacgctca tgttacgaca attgatcgtt tcgatgtcat gatcgagaaa
     1141 gctaaaaaaa actatgaacg tctaggactg acagataaag tgactttgct tgaaggtcaa
     1201 gcagcagata tcttgccgga gttgtctggt ccgtatgact ttatttttat ggatagtgca
     1261 aaatcaaaat atattgaatt tttacctgaa tgcttacgtt tgttaagaaa aggtggcgtt
     1321 ttgatggtag atgacatctt ccaaggagga acgatcttgc tcccagatga agagattccc
     1381 cgtggcaaac gagctatcca tcgtaaatta aatgaatttc ttcgtgttgt gatggatcat
     1441 cccgatttga catcgacaat cttgccatta ggtgatggtg tgatcttaat gacaaaggaa
     1501 tcagaaacaa tcgagttgtg atacatgatt atggcagcct gtagataatc gattgaatcg
     1561 agggctcaat tcgaacttga tgtaaaagtt tctatatttg taagtcaatt aaaggataca
     1621 ggaaatctaa ataaacagga gtagcatgaa gtcaatgtag ctcctgtttt caattgataa
     1681 ccttagaaca gctgaaggag aatgtctcgt tttaaaagat tgatttagta gttgggccaa
     1741 aataattcat tatttgctaa ttaaataact atttcgtatt gacagaagca atttaattat
     1801 ctataattat tgatgttccg ctgattcttg tcatagtagc tcagctggat agagcatccg
     1861 ccttctaagc ggacggtcgg gggttcgaat ccctcctgtg acgctaaaaa accgttagaa
     1921 actgaggttt ctaacggttt ttctttgttt tttgtgccaa tattgtttgt tttcaaaggc
     1981 aaataaaata aaaaaacatc cttatcgagt acaattataa ggagcaaaaa aataaaactc
     2041 atcagaaaag aggaagaaga tatgacgata ctatctagaa ttttagtgac tctagttgca
     2101 attgaatttt tttatatcat gtatatcgaa acggtgagaa ctgattctga cacgacaagt
     2161 agggttttta aaatgagtaa agaagagtta agcagaaaat ctgttcaaac attgtttaag
     2221 aaccaaggag tgtacaatgg actattagga gtgggactac tttatggagc ttatctttct
     2281 tccgcatcta aagaaatcac aagtatgcta ttaatatcta ttttttttgt tgcattatat
     2341 ggcagtttga ctagcgatcg ttggatttta ctcaaacaag gtgggctagc tctgttggca
     2401 ttgctttcta ttttcttata aatatagaaa aaataagaat ttatctaaca ggaaactttg
     2461 tgaaaaatat tactttatct catgaaatat gatattctaa tgaatggtat tttagaaaat
     2521 ttcatgaaaa aggagttaga taggtgttca aaaattatgt ttcctcacta aaaaaagaat
     2581 tttcaggtta tgatctttca agatttcaga aagatctttt ggctgggatc acagtagctg
     2641 ctgtagcatt gcctttagcc ttggcttttg gggtatcaag cggagctgat gcggccgcag
     2701 gtttgattac ggctatcatt gccggtatcg ttattggcgg tttatcaggc ggtttttatc
     2761 aaatatcagg tccgacaggt gcgatggcag ctatcttgat gtctattgcg gcaacaaagg
     2821 gaatgcaagg tgtattgctt gctacttttt tagcgggtct atttttactt gcagcaggac
     2881 ttttccgatt aggaacactg acttctttta tcccagcacc cgtaattacg gggtttactt
     2941 caggtattgc tatcattatt gcattaggtc agatcgataa tttatttggt gttcactcgg
     3001 aaggtacaaa cgttattgaa aaactaagta gttatcaaac gataggattt ccgataaaca
     3061 cagcctcttt gatcatggga gggctagtca ttttagggat gtttatctat ccaaaaaaat
     3121 gggcgaaacg aatgcctagt tcgctgctgg ctatcatttt ggcaacagca gttatgctat
     3181 tgttccattt accagtagca actgtgggta agattccaca aacattgatc agtagtaatc
     3241 gtttgaatat gggagatttt agcttttctg ccttgcaaca agtggcagtt ccagctatta
     3301 gcattgcttt attaggaatg attgaaagct tgctatgtgg tgcttcggct ggccgaatgg
     3361 caaataagcc cttagatagc aatcaagaat taatggcgca aggaattgga aatctgttgc
     3421 ttcctttctt tggcgggatt cctgctactg cggccatcgc ccgtacaagc gtggccatca
     3481 aatctggtgc acaaactaga ttagctggta tgatacatgc agttgtctta ctgctctcca
     3541 tgcttgtttt tgcgccagtg atgtcacaga ttccaatgcc agcacttgca ggtgttttga
     3601 ttgtgacggc ttggcgtatg aatgaatggg aaacgatcaa ggagctattt actaataaat
     3661 attggtcagc agttctattg tttatcctta cgatgatttg tacagttatc tttgatttaa
     3721 gtattgctat cgtgatcggg gtgatcggcg gctgtgtatt ttttgttgtc aaaagcgctg
     3781 ctatcacgat ttcattagaa acgatcgatt ggcaaagaat ggggctgcca gaaacggaaa
     3841 agctgaataa ctggacagta gtgtatatta gtggtccact gttttttatg tcttcagaaa
     3901 aactcaaaaa taaattggaa gaactaaatc atcacgatgg tgtcattttc tccatgcgag
     3961 gcgtaccaag tattgatttg acggcacgtg cagtttttga tgaatttcaa gaaaaagcag
     4021 agcaaagagg acaaacgatt atctatactt ccttgcagcc agaagtagaa aaacaacttt
     4081 ctcacttgtg ggaacataca ttcacgcatc aacatcaaac agttgctcat gcgttgacag
     4141 ctttacatgc gaaatatact gcaattagcc attaaaacaa tgaaaaagaa cagacaagac
     4201 tgtaaactga agattttatg gtcttgtctg ttctttttaa tattgctgta aaagtgaagc
     4261 tagtacttgc cagtcttgat ggataacagg tacaagggag cgattgtaga aaatagctgc
     4321 tggatgaaaa agtggaagaa ttcgatagtt tttttctgac cattcgtagg catccttttg
     4381 ttctgttaat tgtaagacag gccctgtata gagttgacca tgatttttgg taaccgtata
     4441 ttctttgcca agtaaacgtt gaagaccaat gtttccaagt gtcgcaatta attttggctg
     4501 gaccttcatc agttcgtaat ccaatattgg tgcatgcgca aatacttcgg aacgagtagg
     4561 tgtccgattt ggataaacag tttctgactg ttgtgtccgt ttattgatcc gatgagtcac
     4621 gcgatacggg cggctcctta cagcactggt gatatacacc tcttctcgtg ttaagccagt
     4681 tgaagaaagt gcctgcatca attcttttcc agcttgaccg ctaaaaggaa catgcgtatc
     4741 aatctctgtt ttccctgggg cttctcccac gagcatcagt ttaggatgaa gaggtccttg
     4801 cccagcgata aatccttcta caggacggcc gttcattctt aaagaagctt cttgtatcag
     4861 ttcttttggg tattccattt atgctcctcc tttttctttt attataagaa taaaagaaac
     4921 acaatgcgac tattttattt ggtagaactg tgaggataga aaagcagaag tattgcttga
     4981 atttttgttt tactttttga ttttaaattt agttgactaa cggttgctgt tctggtaagc
     5041 tagtactgtt gtaattgtgg actccacagc tacaaccgct cagaacaagt aataagcaca
     5101 gcatatgctg tcacttcgga tggcgagtct aagtatatca gaaggaggtg ctttatagca
     5161 tgtacgcaat tattaaaact ggtggtaaac aagtaaaagt tgaagtggga caagcaatct
     5221 atgttgaaaa acttgacgtt gaagcaggag aaaaagttgt ttttgacgaa gttatcttag
     5281 taggcggaga atctacaaaa gtaggcgctc caactgttgc aggtgcaact gttgaaggta
     5341 ctgttgaaaa acacggcaaa caaaagaaag tcgttacttt caaatacaaa cctaaaaaac
     5401 attcacaccg taaacaaggt catcgtcaac catatacaaa agtggttatc gacgcgatca
     5461 acgcttaata gcgtttgaga aagaaggcct atatatgatc aaaggaacat ttaagcgaaa
     5521 tgacgcaggt cagatcgttt cattcacttt gaccgggcat gctgatgctg gtccttatgg
     5581 aagtgatatc gtttgtgcgg gtgtttctgc gttagcgatc agcactgtca acgggattgc
     5641 ctcattagcc ggttttgagc cgattgttga aatgaatgaa gaagaaggcg gttatcttta
     5701 taccgaagtc acttcaggaa tgacacaaga acaaaacaat attgctgaga ttctattaga
     5761 aaatctttta ttaggattac aatcgataga agctgaaaac tcagaatata tccaaattaa
     5821 aacaattaat gataaatagg aggtgcagac catgttgtta tctatgaatc tacaattatt
     5881 tgcccacaaa aaaggtggcg gttctacatc taacggccgt gactcagaat caaaacgtct
     5941 aggtgctaaa cgtgctgatg gacaaacagt tacaggtgga tcaattcttt accgtcaacg
     6001 cggtacaaaa atctatccag gtgtaaacgt gggtatcggt ggagacgaca ctttatttgc
     6061 aaaagttgat ggcgtagtac gtttcgaacg taaaggccgt aacaaaaaac aagtgtctgt
     6121 ttatccagta gctcaagaag cttaattgaa tcttatgatt aaagaggttg tgacaagact
     6181 tttgtcacag ccttttttgt tta
//
LOCUS       DAFBVQ010000102         6135 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.107, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000102 DAFBVQ010000000
VERSION     DAFBVQ010000102.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 6135)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6135)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..6135
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.107"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(207..1169)
                     /locus_tag="LLC22_002672"
     CDS             complement(207..1169)
                     /locus_tag="LLC22_002672"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004233175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5435880.1"
                     /translation="MVAKLTDVAELAGVSPTTVSRVINNKGYLSEKTKQKVHEAMKTL
                     GYKPNNLARGLQGKSPQLIGLIFPNISNIFYSELIEYLEIELFKHGYKTIICNSQNDP
                     AKEREYIEMLEANQVDGIISSSHNLGIADYERVRAPIVAFDRNLAPNVSIVSSDNFEG
                     GKLAAKTLQKNGCQNTIMITGNDNTDSPTELRALGFSFQNPNGKIFKIPNNLSTIRRE
                     MEIKSTIINHKPDGIFVSDDLTAILTMKIAHQLKLNIPEDLKIIGYDGTSFIEKFFPQ
                     LTTIRQPIDEIASLIVDILLKKIKGEKTNKDYILPISILSGGSI"
     gene            complement(1171..2610)
                     /locus_tag="LLC22_002673"
     CDS             complement(1171..2610)
                     /locus_tag="LLC22_002673"
                     /EC_number="3.2.1.26"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737355.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sucrose-6-phosphate hydrolase"
                     /protein_id="HBK5435881.1"
                     /translation="MNLPREIRYRAYSDWTKDEMDKIKDNVKRSPWRASYHIEPKTGL
                     LNDPNGFSFFNGKYTLFYQNWPFGAAHGLKEWVHNESDDLVHFHVTGAELLPDTKRDS
                     HGAYSGSAYEIEGNLFLLYTGNVRNENWERDTLQIGAWMDKDYNITKGENVLIHKPAD
                     VTDHFRDPQMFNYEGQLYAIVGAQNLEKSGFIKLYKADDNNVETWEEVGNLDFGGTGS
                     EYMIECPNLVFVDKKPVLIYCPQGLDKSELNYGNIYPNTFKICQSLDIEKVKLVGASE
                     IQNLDYGFEAYATQGFNTPDGRALIVSWIGLPDIDYPTDKYDYQGAMSLVKELSIKDG
                     KLYQYPVEAITSLRASSEQFTAKAETNNTYELELTFPPNQKSELLLFSDSKGNGLSLI
                     VDTKEGKIILDRSKAGIQYATDFGTIRECSIDTKETTANIFVDNSIIEIFINKGEKVF
                     TSRVFPENHQNGIQIKSGEPTGKYFELKY"
     gene            2795..4741
                     /locus_tag="LLC22_002674"
     CDS             2795..4741
                     /locus_tag="LLC22_002674"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS beta-glucoside transporter subunit IIBCA"
                     /protein_id="HBK5435882.1"
                     /translation="MNYSKVASDVIQAVGKDNLIAAAHCATRLRLVLKDDTKVNQKAL
                     DENPDVKSTFKINGQYQVIIGAGDVNFVYDELIKKTGLSEISTDDLKQIASKDKKFNP
                     IMALIKLLSDIFVPIIPALVAGGLLMALQNFLTAAGLFGPKSIEEMYPAIEGISSMIQ
                     LMSAAPFMFLPILVGISAAKRFGANQFLGAAIGMIMTTPDLGGSTEYWNIFGYHVSQT
                     NYAYQVIPVLAAVWILSILEKFFHKKLPSSIDFTFTPLLSVMITGFLTFTVIGPVMLL
                     LSNGITDIIVWLYNTTGFIGMGIFGGTYSLIVMTGLHQSFPAIETQLLSAWTNGIGHG
                     DFIFVVASMANVAQGAATFAIWFLTKNSKTKSLASSAGVSALLGITEPALFGVNLKYR
                     FPFFCALIGSGIATAVAGLLKVVAVSLGSAGFLGFLSINATSIPFYVLCELISFVVAF
                     AITYFYGKTKAAGIFKAEEIAEQTPVNSSKVATTDPISTDVESTQTKVSSETIVSPIS
                     GKVISLSSVNDPVFSSEAMGKGIAIKPNGNTVHSPVDGTIQLTFETGHAYGIKSNNGA
                     EVLIHIGIDTVSMGGKGFTQKVTTNQKVRKGDILGAFDRSMIEKEGLDDTTMIIVTNT
                     SDYSEVNIVAENTVTEGTDLLEIK"
     gene            5005..5877
                     /locus_tag="LLC22_002675"
     CDS             5005..5877
                     /locus_tag="LLC22_002675"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ROK family protein"
                     /protein_id="HBK5435883.1"
                     /translation="MLYGAIEAGGTKFVCAIGDEEMTIKERVSFPTTTPEETMPLVID
                     FFKQYQADLAGIGIGSFGPIDIHRDSATYGYITSTPKLAWQNFDFIGTMKKEFPIPIS
                     WTTDVNAAAYGEYVFGSGKGLSSVVYYTIGTGVGGGALQEGRFIEGFSHPEMGHMLVV
                     PHPKDDFAGSCPFHGNCLEGMAAGPAIENRLGKKGQEVAEDDPYWEIEASYIAQCAYN
                     TTLMFSPDVIIFGGGVMKQRHMLQNVHDAFAKLVNGYVETPELSKYIVTPALEDNAGT
                     LGCLALAREAVLHS"
BASE COUNT         1947 a         1054 c         1083 g         2051 t
ORIGIN      
        1 cgtccaattt cgtaaaacaa ccgtaacagt tgtgtaaaaa tatcatttta gagcatgaaa
       61 aaaggagtgg atttctccac tccaaaaaag tctaactttt gggggtcact acaagttgac
      121 aactcctttt tgtttacaaa tcaattggat atctacaaat tgtattttct aacgaatttt
      181 atagacatta aaaaattaat ttaacgttaa atacttcctc cagaaagtat tgagattggt
      241 aaaatataat ccttatttgt cttttcgcct ttaatttttt tcagaagaat atcaacaata
      301 agacttgcaa tttcatcaat tggttgtctt attgttgtca attgtgggaa aaatttctca
      361 ataaaagagg taccatcgta tccaataatt tttaaatctt ctgggatatt aagtttaagt
      421 tgatgagcaa ttttcatagt gagaatggct gttaaatcat cagaaacaaa aataccatct
      481 ggtttgtgat ttataatagt tgactttatt tccatttcac gacggatagt agacagatta
      541 ttaggaattt tgaaaatttt tccatttgga ttttgaaaag aaaaacctag tgcacgtaat
      601 tctgtgggag aatccgtgtt atcatttcct gtaatcataa tggtattttg acaaccattt
      661 ttttgtaaag tcttagctgc aagttttccc ccttcaaagt tatctgaaga aacaatggaa
      721 acattaggag ctaaatttct atcaaaagca acaataggtg ctctcacacg ctcataatca
      781 gcaattccaa gattatggct tgatgagatt atgccatcaa cttggttggc ttcaagcatt
      841 tcaatgtatt ctctctcttt agcaggatca ttttgactat tgcaaataat cgttttatat
      901 ccatgtttaa ataactctat ttcgagatac tcaatgagtt cagagtaaaa gatattacta
      961 atattaggaa aaataagacc aataagctga ggtgactttc cttgaagtcc acgtgctaaa
     1021 ttatttggtt tataaccaag agttttcata gcttcatgaa ctttttgttt tgttttttct
     1081 gataaatatc ccttattatt aatgacgcgt gaaacggttg ttgggctaac tccagctaat
     1141 tcagcgacat cagttaattt tgctaccatt ttaatatttt aattcaaagt attttccagt
     1201 aggttcgcct gatttgattt gaataccatt ttggtgattt tcagggaata cacgactagt
     1261 aaacactttt tctcctttat taataaaaat ctcaatgatt gagttatcta caaaaatgtt
     1321 agcagttgtt tctttagtat caattgagca ttcacgaatc gtaccaaagt cagtggcata
     1381 ttgaatgcct gctttgctgc gatctaaaat aatttttcct tctttggtat ctacaatcaa
     1441 gctaagtcca tttcctttac tatcagagaa aagaagtaac tccgatttct gatttggagg
     1501 aaaagttagt tcaagctcat aagtattatt tgtttctgct tttgctgtaa attgttcaga
     1561 actagcacgt aatgatgtaa tagcttctac tggatattgg taaagtttac catcttttat
     1621 tgaaagttct tttacaagac tcattgctcc ctgataatca tacttatcag ttggataatc
     1681 gatatcaggt agtccaatcc aactgacaat cagagcacga ccatcaggag tattgaatcc
     1741 ttgagtcgca tacgcttcaa atccataatc aagattttga atttctgaag cgcccacaag
     1801 ttttactttt tctatgtcaa gcgattgaca gatcttaaaa gtattcggat agatattccc
     1861 ataatttagc tcagatttat ccaacccttg aggacaataa atgagaacag gttttttgtc
     1921 tacaaatact agatttggac actcaatcat gtattctgaa ccagtgccgc caaaatcaag
     1981 gttgccaact tcctcccatg tttccacgtt attgtcatcc gctttgtaaa gtttgataaa
     2041 gcctgatttt tctaaatttt gtgctccaac aatcgcatac aattgtcctt cataattaaa
     2101 catttgtgga tcacgaaaat gatcagttac atcagcaggt ttatgaataa gaacattctc
     2161 acctttcgta atgttgtagt ctttatccat ccatgctccg atttgaagtg tatcacgttc
     2221 ccaattttca tttcgaacgt ttcctgtata gagtaagaat agattcccct ctatttcata
     2281 tgcagaaccg gaataagcgc cgtggctatc tcgttttgtg tctggaagaa gttctgctcc
     2341 tgttacatga aaatgaacta aatcatctga ttcattgtgt acccattctt tcaacccatg
     2401 agcagctcca aatggccaat tttgataaaa aagcgtatat tttccgttaa aaaaagaaaa
     2461 accattagga tcgtttaaca atcctgtttt aggttcgata tgatagctag cacgccaagg
     2521 tgatcgtttt acattatcct taattttatc catctcatct ttagtccaat cagaataagc
     2581 acgatatcgt atttctcgag gtaagttcat attttactcc ttcaatttat ctttttacaa
     2641 ctagtatggt aaacgttttc cgttgaaaaa tcaatcattt catttaaaaa aataaactat
     2701 atgacaaacg tttgacatat ttttaagata tgctaaaata aatttgcatt tcagtgaacc
     2761 gttttcacgt aaaaataaaa aaggagtgat tcgaatgaat tacagtaaag tagcttccga
     2821 cgtaatacaa gcggtcggaa aagataacct tattgcagct gcacactgcg ctacacgtct
     2881 tcgtctcgta ctaaaagatg acacgaaagt gaatcaaaaa gctttagacg aaaatccaga
     2941 tgtgaaaagc acatttaaaa ttaatggaca atatcaagtg attatcggtg caggtgatgt
     3001 taatttcgtt tatgacgaac ttatcaaaaa aactggactt tcggaaattt caacagatga
     3061 tttaaaacaa attgctagta aagataaaaa attcaacccc attatggcat taattaaatt
     3121 attatcagat atttttgttc caattatacc tgcccttgtt gcaggtggtt tattaatggc
     3181 attacaaaac tttttaacag ctgctggact ttttggacca aaatcaattg aagaaatgta
     3241 tcctgcgatt gaaggtattt cctcaatgat ccaactgatg tccgctgcac cattcatgtt
     3301 cttaccaatt ttagtaggta tttcagctgc taaacgtttt ggagcaaacc aatttcttgg
     3361 tgctgcaatt ggtatgatca tgacaacacc agatcttggt ggctcaactg aatattggaa
     3421 tatttttggt tatcatgttt cacaaacaaa ctatgcttat caagttattc cagttttagc
     3481 agctgtttgg atattatcta tattagaaaa attctttcat aaaaaattgc catcatctat
     3541 tgactttaca ttcacgccat tattatcagt aatgattact ggatttttga ctttcacagt
     3601 tattggccct gtaatgttat tgttgtctaa tggaattaca gacattattg tttggctata
     3661 taacactact ggatttattg gaatgggtat ttttggagga acatattcac ttatagtcat
     3721 gactggttta catcaatcat ttccagctat tgaaactcaa ttactttcag cgtggacaaa
     3781 tggtatcgga catggagact ttatctttgt agttgcatct atggcaaacg ttgctcaagg
     3841 tgctgcaaca tttgccattt ggttcttaac taaaaattct aagacaaaaa gtcttgcttc
     3901 ctctgcgggt gtctcagcac ttcttggaat tacagagcct gccttgttcg gagttaactt
     3961 aaaataccgc tttccattct tttgtgcttt aattggttca ggaattgcta cagcagtagc
     4021 aggattactt aaagtagttg ctgtttcact tggttcagca ggtttcttgg gatttctttc
     4081 aattaatgca acatctattc cattttacgt attgtgtgaa ttgattagct ttgtagttgc
     4141 ttttgcaatt acttacttct acggtaaaac aaaagctgct ggtatcttta aagcagaaga
     4201 aattgctgaa caaacaccag ttaattcttc aaaagtagca acaacagatc caatatctac
     4261 tgatgttgaa tcaacacaaa caaaagtttc atcagaaaca attgttagtc ccatttctgg
     4321 taaagtgatt agtctttctt cagtaaatga tccagtcttt tcatcagaag ctatgggaaa
     4381 agggattgcc attaaaccaa atggaaacac ggtccattct ccagtagatg gtactattca
     4441 actcacgttt gaaactggac atgcttatgg tattaaatca aataatggtg ctgaagttct
     4501 aattcatatt ggtattgata ctgtatcaat gggaggaaaa ggatttacac aaaaagttac
     4561 tactaatcaa aaagttagaa aaggcgatat tcttggagca tttgaccgtt caatgattga
     4621 gaaagaaggt cttgatgata caacaatgat tattgtgacc aatacttcgg attattcaga
     4681 agtaaatata gtagctgaaa atacagtcac tgagggtact gatttacttg aaatcaaata
     4741 aatatatttc cctgagtaaa gatggaattt tctttccaaa atcaaataat atagattaat
     4801 caaatatttg agaataacat tttatttaat cttttcatat atcaattgta tgaaaaatta
     4861 ttagaatttt aaaaaatgat aaaaattcaa aaagaaaaaa tagtagttat ttacttgtca
     4921 tgttactaaa taaaaaaata atttaaatat gatatatagt catttattta gtgatttcat
     4981 tctaaaataa agggagaaat gtctatgcta tacggtgcaa ttgaagcagg cggcacaaaa
     5041 tttgtgtgtg ccattggcga tgaagaaatg acgatcaagg aaagagtgag ctttccgaca
     5101 acgacacctg aggaaacaat gcctttagtc attgacttct tcaaacaata ccaagcagat
     5161 ttagcaggga ttgggattgg ctcatttggg cctatcgata tccatcgcga ttccgccact
     5221 tatgggtaca ttacctcgac cccgaaattg gcatggcaaa attttgattt catcggtacc
     5281 atgaaaaaag aatttccgat cccgatttct tggacaacag atgtcaatgc ggctgcctat
     5341 ggtgagtatg tcttcggcag tggcaaagga ttgagcagtg tcgtttacta tacgatcggt
     5401 acgggtgttg gcggcggtgc cttacaagaa gggcgcttta tcgaagggtt tagtcatcca
     5461 gaaatggggc atatgctcgt cgtccctcat ccaaaagatg actttgctgg cagctgtcca
     5521 tttcatggca actgtttaga agggatggcc gctggacccg ccatcgaaaa ccgcttaggg
     5581 aaaaaaggac aagaggttgc agaagatgat ccttattggg aaatcgaagc ctcctatatt
     5641 gctcaatgtg cctacaatac aaccttgatg ttttctccag atgtgatcat ttttggcggt
     5701 ggtgtgatga aacaacgcca tatgctgcaa aacgtccacg acgcatttgc aaaattggtc
     5761 aatgggtatg tcgaaacacc tgagttaagc aaatatatcg tgaccccagc attagaagac
     5821 aacgctggaa cgctcggttg tttggcattg gctcgagaag cggtcttaca ttcataaacg
     5881 aaaaaaggct cttcgacatt tagtgttggt agagaaagat acaactgaaa atttagtcat
     5941 aaccagttag gcagagtgct taactggttt ttgttttact tggaagatca agccttgaat
     6001 gagataaatt cttgctcgaa agttatggaa atttcgatag ccgtaggcca cttgtattgt
     6061 gcaatagttt tttacaaaaa aaagggggtg cggatatttt tttggacctt tttaacaaat
     6121 atatctttgc ttctt
//
LOCUS       DAFBVQ010000103         5878 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.108, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000103 DAFBVQ010000000
VERSION     DAFBVQ010000103.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5878)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5878)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5878
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.108"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            642..1376
                     /locus_tag="LLC22_002676"
     CDS             642..1376
                     /locus_tag="LLC22_002676"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301131.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5435884.1"
                     /translation="MQNTFQSKSLYYQLVEILKQRIENSMVAHDKLPSERELTSFYGV
                     SRTTVRLALQELEKMGYIYRQHGKGTFVSELRTNATDLAGAYSFTEQMRAMGKHPETK
                     ILAFKKIEATKYLASHLNVQLGEPLFQLDRLRLADDLPMMIEKSYLPVKLFMSLSQEI
                     LFLKPLYNLFSENFNQIVRLADEEFYASIVQKEDSELLNIPEGSPVLHLVRSTYNLEN
                     EVIEFTLSVARADKFHYKIRHLRSTN"
     gene            1392..2561
                     /locus_tag="LLC22_002677"
     CDS             1392..2561
                     /locus_tag="LLC22_002677"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301130.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5435885.1"
                     /translation="MFMFSKEELRKLGAENTTREIRQQPELWHETFDRYQETVADLDR
                     LFTDAKQHAGERPIRVIFTGAGTSQYVGDTLIPFLTSQGNTNQFIFQSIGSTDIVATP
                     KEYLIPDETTILVSFARSGNSPESLAAVKMANQLVNKIYHIVITCAPDGLLATQMPTK
                     KENLVLLMPNKANDAGFAMTSSFSCMTLTALLIFDQASNQQKERYVHQLSRLGEEVIQ
                     RESEIQGYLASDFHRIIYLGSGSLGGLTREAQLKVLELTAGKIATVFDTSLGFRHGPK
                     SFVNEQTLVFLFVSNDSYTQKYDVDMLEEIKNDGIAQRVVGIGQKGSLFSGDSFELVA
                     DSLLPDGYLALADIMVAQTIALLCSVKVGNTPDTPSPSGTVNRVVKGVTIYPYEK"
     gene            2577..3572
                     /gene="lacD"
                     /locus_tag="LLC22_002678"
     CDS             2577..3572
                     /gene="lacD"
                     /locus_tag="LLC22_002678"
                     /EC_number="4.1.2.40"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tagatose-bisphosphate aldolase"
                     /protein_id="HBK5435886.1"
                     /translation="MLEWSENKRQAMERLSTPEGIITALAIDQRGALKKMMSALGMEA
                     TKEKIEQFKTLISQELTPYASAILLDPEYGLPAAQKRAAASGLLLAYEKTGYDQTVPG
                     RLPDLLSDCSVLRLKELGADAVKFLLYYDYEEAEEINRQKQVFVERIGSECMAEGLPF
                     YLELLSYDAKNVDTKSLSYAKAKPRKVIEMMKEFSKTQYKVDVLKVEVPVNMSFVEGN
                     ATGEIAYTRQEAAAYFKEQSDATDLPYIFLSAGVSAALFMETLRFAKHAGARFNGVLC
                     GRATWKDAVAPFVEKGEAATLEWLTEQGTQNIRQLNEVIRETAIPWYEKVSESTC"
     gene            3651..4577
                     /locus_tag="LLC22_002679"
     CDS             3651..4577
                     /locus_tag="LLC22_002679"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="haloacid dehalogenase-like hydrolase"
                     /protein_id="HBK5435887.1"
                     /translation="MNKRLLDYSASDFLKAKPMELKQAILASEGRTIMAENVPSSCPY
                     MGKSVTNAELERAAGADLILFNALDLFNPQISGVPLTLKENPIIWIKKALGRAIGVNL
                     EPVDKEVLMSENRTEISSGRIVSPETLKKANELGFNFICLTGNPGTGVSNRTIEKAIT
                     LSKSIFNGLIIAGKMHGAGVDEPIMNLDIAKRFIKTGVDILLVPAPYTVPYFMESDLR
                     GIVDYIKDFNRNKSIEEKVLVLTANGTSQDSSDQETIKKIALASKACGADIQHIGDSL
                     NGICLPENIFALGQAIRGYRHQIIMLGKSNYR"
     gene            4596..5846
                     /locus_tag="LLC22_002680"
     CDS             4596..5846
                     /locus_tag="LLC22_002680"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301126.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5435888.1"
                     /translation="MIDKVQKIAAKISNQRHLLALRDSMAAVMPLIIIGSFFMLLANF
                     PIEGFTKWLSEIGVQSFLNKASDSTFGIIGLAVTYSLGHNLAKTYGVDSLSAGLLSLS
                     GYVLLTPLLDADGSIGFPTKYFGTSGLFVGIIVALVSTEIFRWFVLKNITIKMPASVP
                     PNVSRAFVAIIPGFFVVLLWFIVVVICYKLGIENVHALIADTLAKPLSLLTKTLPGII
                     LVILIQCFFWMFGIHGAQVTGPIIEPLLLQNSDVNRIAYQAGKELPNIITYEFLYNFV
                     FSGGAGCLFALAILTFFFSKSQENKTLGKLSIAPVSFQVAEPLLFGFPTILNIKMLIP
                     FVTAPVVTTLITYFSMSMGLVAKPVGATIPWTTPPIIAGFLASGGRISGAVIQVITIA
                     INVLIYYPFFKLDDNAKLKSEKND"
BASE COUNT         1968 a          955 c         1204 g         1751 t
ORIGIN      
        1 agtttgaaaa atgctatttc gaggtagaag gatattatat aagcacggtt gactaaacga
       61 agtgataata aaaaaagtta ttcaagaata agaaaaatta tgatacgaat tcagataaac
      121 tggagaatac agagaccttt aaaagggata agaaacaaca taaattcctc ttaagagaga
      181 acgaaaggac aaagccagca acttgataca cgagctagta ttagaggaat ttattctcat
      241 agactccctt ttgaatacgt ttcaacttta attttcatgt tcataaatga tttgaaacca
      301 aagcaaatgc gttgcacttt tcctccgtct tccgaaaatc gttcaattca ctggtaagta
      361 gtcatttgat agtttgaggc aaattgttga ttgatgaagg gtaggagcta aaaaaagata
      421 ccagttgaag agagaaaaag aaaaaaatag agggtgttct tgaatgaaaa aagttggaaa
      481 attatttttc atttcctttt attcctatta aagtcagtga tgtcaatcat attaacaaga
      541 ctaaaaatga aaataaaaaa aagattgttc ttagtattga ctcataaaaa ataccactac
      601 tatacttaca ttgtggttat agccagttag gagagacatc gatgcaaaat acctttcaat
      661 caaaatcact ttattatcag ctggtagaaa tattgaaaca acgaatcgaa aacagtatgg
      721 tcgctcatga caagctgcca tcagaaagag agttgaccag tttttatggc gttagtcgca
      781 cgacggtgcg actagcattg caagaactgg aaaaaatggg ctacatttat cgacaacatg
      841 gaaaaggaac ctttgtttcg gaattaagga caaatgcgac tgatctagct ggcgcatata
      901 gttttaccga acaaatgcgg gcaatgggca aacatcctga aaccaagata ttggccttca
      961 agaagattga agcaactaaa tatttagcga gtcatctgaa tgttcaacta ggtgagcctt
     1021 tatttcaatt agaccgattg cgcttagctg atgatttgcc aatgatgatc gagaaatcct
     1081 atttgccagt gaagctattt atgtcccttt ctcaagaaat tctatttctg aaacctttat
     1141 ataatttgtt ttcagagaat ttcaatcaaa tcgtacggtt ggctgacgag gaattttatg
     1201 ccagcattgt ccagaaagaa gatagtgagt tgctaaatat tccagaagga tcaccagtgc
     1261 tccatttagt tcgctcaacc tataatctcg agaacgaagt gattgaattt acattaagtg
     1321 tagcgcgggc tgataaattt cattataaga tcaggcatct gcgttccact aactgaattg
     1381 gaggaaagaa aatgtttatg ttctcaaaag aagaactacg aaagctagga gcagaaaata
     1441 ctacccgaga aattcgacag caaccggaac tgtggcatga gacgtttgac cgttatcaag
     1501 aaacagttgc agatttagat cgtttgttta cggatgcgaa acaacatgct ggagagcgac
     1561 caatccgagt catttttaca ggggccggaa cctcgcaata tgtgggagat acactaattc
     1621 cgtttcttac tagtcaagga aatacgaacc agtttatttt tcaaagtatt ggttcgaccg
     1681 atatcgttgc tacgccaaaa gaatacctga ttcctgatga gacaacgatc ttggtctcat
     1741 ttgcccgtag tggaaatagt ccagaaagtc tagccgcagt taagatggcc aatcagctgg
     1801 tcaacaagat ctatcatatc gtgatcacct gtgcaccaga cggattattg gctacacaaa
     1861 tgcctacaaa aaaagaaaat ctagttttac taatgccaaa caaagccaat gacgctggtt
     1921 ttgctatgac aagcagtttc agctgtatga cgctgactgc gctacttatt tttgatcaag
     1981 caagcaatca gcaaaaagaa agatatgttc atcaattaag ccgactagga gaagaagtca
     2041 tccaacgaga atcagagatc caagggtatc tggcatcaga ctttcatcgc atcatttact
     2101 taggttcggg aagcttaggc ggattgacta gagaagcgca attaaaagtt ctcgagttaa
     2161 ctgctggaaa aatcgcaacc gtatttgata catctttagg attcagacat ggtcccaaat
     2221 cttttgtcaa tgagcaaaca ttggttttcc tgtttgtcag caatgactca tatacgcaga
     2281 aatacgatgt agacatgctg gaagaaatca aaaatgacgg tattgcccaa cgcgttgttg
     2341 gaattggtca aaagggttca ttgtttagtg gtgattcctt tgaattagtt gcagattcgt
     2401 tactgccgga tggctatctt gctttagcag atatcatggt agcccaaacg atcgcattac
     2461 tttgttcggt gaaggttggt aatacaccag atacaccatc gccaagtgga acagtcaatc
     2521 gtgtggtcaa aggcgtaacg atttatccat atgaaaaata ggaaagagtg tgaagcatgt
     2581 tagaatggtc ggaaaataaa agacaagcaa tggaacgtct atcgacgcca gaaggcatta
     2641 ttaccgcttt ggcgatcgat cagcgaggcg cgctgaagaa aatgatgtcg gctttaggga
     2701 tggaagcgac aaaggaaaaa attgagcagt ttaaaacact aatttcccaa gaattgactc
     2761 cttatgcctc agcaatttta ttggatcctg aatacggact gcctgctgca cagaagcgtg
     2821 cagcagcgag cggtctgctg ttggcatatg aaaaaactgg ttatgatcaa accgtacccg
     2881 gccgcttgcc ggatctgctg tcggactgtt cagttctgcg attgaaagag ttaggtgcgg
     2941 atgcggtgaa atttttactg tattacgatt atgaagaagc agaggaaatc aatcggcaaa
     3001 agcaagtttt tgttgaacga attggaagcg aatgcatggc tgaaggactg ccattttatt
     3061 tagagttatt gtcatatgat gctaaaaatg tagatacgaa atcgctttcc tatgccaaag
     3121 caaaaccgcg caaagtgatc gaaatgatga aagaattctc gaaaacccag tataaagtag
     3181 atgtcttaaa ggttgaagta ccagtaaaca tgtcatttgt tgaaggaaat gcaacagggg
     3241 agatcgccta tacacgtcaa gaagctgccg cttattttaa agaacaaagc gatgcaacag
     3301 atttgccgta tatcttctta agtgctgggg tatcagcggc attattcatg gagacattgc
     3361 gttttgccaa acatgctggg gcacgattca acggtgtact ctgtggcaga gcaacttgga
     3421 aagatgcagt cgctcctttc gttgaaaaag gagaagcggc aactttagaa tggctgacag
     3481 aacaagggac acaaaacatt cgtcaattga atgaagtgat aagagaaact gccatcccat
     3541 ggtatgagaa agtaagtgaa agcacttgtt aatgtttcta atatattagt agtgataaga
     3601 gatatgtgtg attataattt atcattattg aaactgggag gatattttat atgaataaaa
     3661 gattgttaga ttattcagct tcagattttt tgaaagctaa gccgatggaa ttaaagcagg
     3721 caattttggc ttctgaaggt agaacaatta tggcagaaaa tgtgccaagt agctgtcctt
     3781 acatgggaaa atcagtgaca aatgcagaat tggagagagc tgctggagct gatttaattt
     3841 tgtttaatgc actagatctt tttaatcctc aaatttcagg tgtaccttta actctaaaag
     3901 agaatccaat aatctggatt aaaaaagctt taggaagagc tattggtgta aatttagaac
     3961 ctgtagacaa agaagttttg atgagtgaaa atcgaactga aatttcaagt ggtagaatcg
     4021 tttctcctga gactttaaaa aaggcaaatg aattaggctt taattttatt tgtttaactg
     4081 gaaatccagg aacaggagta tctaatagaa ctattgagaa agcaataaca ttatccaaat
     4141 caatttttaa tggattaatt atcgctggaa aaatgcatgg tgctggtgtt gatgaaccaa
     4201 ttatgaactt agatatagca aaaagattta ttaaaacagg tgtagatatt ttattagttc
     4261 ctgctccata cactgttccg tatttcatgg aaagtgattt gcgaggaatc gttgattata
     4321 taaaagattt taatagaaat aaatctattg aggaaaaagt tctagtacta acggctaatg
     4381 gaacaagcca agactcttct gaccaagaaa ctattaaaaa aattgcatta gcatcaaaag
     4441 catgtggagc tgatattcaa cacatagggg attctttaaa tggtatttgt cttccagaaa
     4501 atatttttgc tttgggtcaa gcaattcggg gatatcgtca tcaaattatt atgttaggaa
     4561 aatctaatta tcgttaatta aggaggaaat gaaagatgat cgacaaagtt caaaaaatag
     4621 ctgcaaaaat tagtaatcaa agacatctac tagctttaag agacagcatg gctgcagtta
     4681 tgccattaat cattattggt tcctttttta tgttattagc aaatttcccg atagaaggat
     4741 ttacaaaatg gttatctgaa attggagtac aatccttttt gaacaaagca tcagattcaa
     4801 catttggtat tattggatta gctgttacct actctttggg acacaatcta gcaaagactt
     4861 atggtgtaga ctcattatca gcaggattat tatctttgag tggatatgtt ttacttacac
     4921 ctttattgga tgcagatggt tctataggat ttccaacaaa atactttggt acctcgggtc
     4981 tttttgttgg tattattgta gcacttgtat ctacagaaat tttccggtgg tttgtactta
     5041 aaaatattac aattaaaatg ccggcaagcg ttccaccaaa tgtaagccga gctttcgttg
     5101 ctattattcc tggctttttt gtcgttctac tatggtttat tgttgttgta atttgttata
     5161 aacttggaat tgaaaatgtt catgctctta ttgcagatac actcgcaaaa ccactatctt
     5221 tactgacgaa aactttacca ggaattatat tggttatact tattcaatgt ttcttttgga
     5281 tgtttggtat tcatggtgca caggtaacgg ggccaataat tgaaccgtta ttattgcaaa
     5341 actctgatgt aaatagaatt gcttatcaag ctggaaaaga acttcctaac attataactt
     5401 atgaattctt atataacttt gttttttctg gtggtgcagg ttgtttattt gcacttgcca
     5461 ttttaacatt tttcttttca aagagtcagg aaaataaaac tttaggtaag ttatcaatcg
     5521 ctccagtaag ttttcaagta gcagagcccc ttctatttgg gtttccaact atattaaata
     5581 taaaaatgtt aattccattt gtaactgcac cagtagtaac aacattaatt acttattttt
     5641 caatgagtat gggattagtt gcaaaacctg taggagcaac aatcccatgg acaactccac
     5701 cgataattgc cggattttta gcttctggtg gacgaataag tggtgcagtg attcaagtaa
     5761 taacaattgc aataaatgtt ttgatatact atccattctt taaattagat gataatgcca
     5821 agctaaaaag cgaaaaaaat gattagaact acctatatgt ttctaactgt agttaagt
//
LOCUS       DAFBVQ010000104         5848 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.109, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000104 DAFBVQ010000000
VERSION     DAFBVQ010000104.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5848)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5848)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5848
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.109"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(459..1088)
                     /gene="udk"
                     /locus_tag="LLC22_002681"
     CDS             complement(459..1088)
                     /gene="udk"
                     /locus_tag="LLC22_002681"
                     /EC_number="2.7.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uridine kinase"
                     /protein_id="HBK5435889.1"
                     /translation="MTKSKPIIIGVTGGSGSGKTSVSRAIFNNFPDHSIMMLEQDSYY
                     KDQSHLSFEERLNTNYDHPFAFDNDLLIQHVGDLLNYKAIEKPVYDYVAHTRSQATII
                     QEPKEVIILEGILILEDERLRDLMDIKVYVDTDDDIRIIRRIKRDMEERGRTLDSVIE
                     QYLTVVKPMYHQFIEPTKRYADIIVPEGGENHVAIDLITTKVASFLNHK"
     gene            complement(1172..1867)
                     /locus_tag="LLC22_002682"
     CDS             complement(1172..1867)
                     /locus_tag="LLC22_002682"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317068.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YjjG family noncanonical pyrimidine
                     nucleotidase"
                     /protein_id="HBK5435890.1"
                     /translation="MKYKTLLFDVDDTLLDFQLTEANALSALFAEQGITLTPEIETSY
                     KALNHHLWQEFEKGRLSREEIIGSRFGLLFQQFGKTVDSDQMEKRYRHYLNQGHDLVP
                     GSLEILKKVHPHADLYIVTNGVSHTQHRRLTDAGMLDYFKDIFVSEAVGAQKPMKEFF
                     DHVFSHIPNFDKKQTVIIGDSLTSDIKGGNMAGIDTIWFNRNKLPEIEEIQPTYRIDS
                     LEELYSLLEIEKD"
     gene            complement(1880..2596)
                     /locus_tag="LLC22_002683"
     CDS             complement(1880..2596)
                     /locus_tag="LLC22_002683"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pseudouridine synthase"
                     /protein_id="HBK5435891.1"
                     /translation="MRLDKLIEEKLETTRKEMKRLFALKQVMIDGTVEFRQNRNVDSL
                     LHQIEVAGEHLETNESYYLLNKPEKAVTAVSDPEKTTVIDLIASADRFQPLYPVGRLD
                     RDTTGLLLITSNGQLGYEMLLPEKKVSKTYQVVVNERVTPADVTAFENGIVFADGYQC
                     KPADLKILKADKHQSTVLLTIQEGKFHQVKKMFLAQGKKVTALKRLSMGPLELDEQLG
                     VGEYRSLTLAEMKKLSIYFK"
     gene            2926..3531
                     /locus_tag="LLC22_002684"
     CDS             2926..3531
                     /locus_tag="LLC22_002684"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="50S ribosomal protein L25/general stress protein
                     Ctc"
                     /protein_id="HBK5435892.1"
                     /translation="MSVSLEVSKREVRPRSLRNKLRHEGKVPAVVYGYKVESTPISFD
                     GLTLSKLLREHGANTVITMDIDGQKVNTLVHKIQTNTFTNHFEHAEFLSVNMSEETEV
                     ETEVVLVGESVGAKSGGVLAQNLYTVVVSATPDKLPERIEVDVTNLELGDSITVADLP
                     KNDDYKFVTDSEEQIAAVVAQSEEESTGEGGEPEVIGSTEE"
     gene            3856..4179
                     /locus_tag="LLC22_002685"
     CDS             3856..4179
                     /locus_tag="LLC22_002685"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010720345.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBK5435893.1"
                     /translation="MFESFDSSRNRYASVGVVSSLPDELIDSIWFIIDLDLKGVIPLE
                     NILTFDLIENRGKVTMHFSQAGSNVEMDIDLPFAYSNQFPAQVYAYDDGTRETILLPS
                     EIRQY"
     gene            4361..5731
                     /locus_tag="LLC22_002686"
     CDS             4361..5731
                     /locus_tag="LLC22_002686"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MATE family efflux transporter"
                     /protein_id="HBK5435894.1"
                     /translation="MRDLTKGSPAKLILMFTVPLLIGNVFQQFYNMIDMIIVGQTLGK
                     NALAAVGATGSLTFLIIGFAQGLTAGLAIITAQRYGAKDYRGLKKSFAASVVISLVVT
                     VILTVLSLLFIRPMLQLMQTPPEILDQAQTFISIILLGIFASVSFNLLSNVIRALGDS
                     RTPLFFLIIAVIINVVLDLIFIIYFGMGVEGAAIATVIAQVSSSVLCLVYIKKKMPLL
                     QLRKKDFKFEKEEFAVHLNAALPMAFQSSIIAVGAIVLQAALNSLGTDVVAAQAAAGR
                     IDQFANQPMMSFGIAMATFTAQNYGAKEYGRILQGVRQTLLMSVGFSLLAGAIVIFFG
                     HFFVQLFVSPSETRVFELAQTYFNINGSLYWILAVLFILRYTLQGLGQSKIPTIAGMM
                     ELLMRSFAAIVLTGMWGYPGAAAASPLAWIGSVAVLLYSYMRSMKQLKHMGEEEHFTL
                     EHAEAR"
BASE COUNT         1665 a         1153 c         1095 g         1935 t
ORIGIN      
        1 gggggtgcga caaaagagct tcttcaaaaa aataagtcga aatctcacac aaattcgaga
       61 aataattttc gtaagtttct tcttatttat tgcatctgac cacttctgtt acaacctctc
      121 gttaaacggt gttcaaaagc ttgcatctac gataataagc ccaacccaac gaaaaacgtg
      181 aggagctgtt ttatttggat gctcttatcg cttgatgcaa agacagcttt tttacaacct
      241 ctacttcacg gtgctcaatc agctgacctt cggtattagc tcaaaaaacg gtaaaatata
      301 aacagctatt ttccgtttct tctttttaat acttaggtca agatgctgtt ttcacaacct
      361 cttgttataa ataaaaaaac agttggctgg tgactgttca aaaagcagaa tccttgcttt
      421 tcaaacggtc gcagtccgtt caactgtttc gctgcgcact atttatggtt taagaaacta
      481 gctacttttg ttgtaatcaa atcaatagca acgtggtttt ctccgccttc tggaacaatg
      541 atatccgcat agcgcttcgt tggttcgata aattgatgat acatcggttt aacaactgtc
      601 aaatattgtt cgatcacgga gtccaatgtg cgtccccgtt cttccatatc ccgtttgata
      661 cgacgaatga tacgaatgtc atcatctgta tctacgtata ctttgatatc catcaagtca
      721 cgcagacgtt cgtcttctaa aatcaggatt ccttctagaa tgatcacttc ttttggttcc
      781 tgaatgatcg ttgcctgact tcttgtatgc gctacatagt catacacggg tttttcaatg
      841 gctttatagt tcagtaagtc gcctacatgc tgaatcagca gatcattatc aaaggcaaat
      901 gggtgatcgt aatttgtgtt caatcgttct tcaaaactca aatggctctg atccttgtaa
      961 taagaatctt gttcaagcat catgatggaa tggtccggga agttgttgaa aatcgcacgg
     1021 ctgacacttg tctttccgct tccggatcca cccgtcacac caatgataat tggcttgctt
     1081 tttgtcattg actaaaacct ctttcgtatc cgttttttca ttctaatcta ttatagcgaa
     1141 aaaacacgaa aatgctatat ttttctgaaa attaatcctt ttcaatttcc aataatgaat
     1201 aaagttcctc taatgaatcg attcgataag taggctggat ttcttcgatt tctggtaatt
     1261 tatttctatt gaaccaaatc gtatcgatcc ctgccatatt tcctcctttg atatcagaag
     1321 tcaaagaatc accaatgatc acagtttgct ttttatcaaa attaggaatg tgggaaaaga
     1381 catgatcaaa aaattctttc atcggctttt gcgctccgac agcttctgag acaaagatat
     1441 ccttgaagta atcaagcatt cctgcatctg ttaatcgccg atgttgcgtg tgcgacacac
     1501 cgttcgtcac aatataaaga tcagcatgcg gatggacctt tttcaggatt tctagacttc
     1561 ctggaacaag atcatgacct tggttcaagt agtggcggta gcgtttttcc atttgatcac
     1621 tatctactgt tttcccaaat tgctggaaaa gtaacccaaa acgactgcct attatttctt
     1681 ctcgtgatag tctgcctttt tcaaactcct gccataaatg atgattcaaa gccttatagc
     1741 tggtttcgat ttctggtgtc aatgtgattc cttgttctgc aaacaaagca cttaaagcat
     1801 tggcttcagt taattgaaaa tctaacaatg tatcatctac atcgaacaat aaagttttat
     1861 atttcatctt tttgacctcc tatttaaaat aaatacttaa ctttttcatc tctgctaatg
     1921 tcaacgatcg atactcgcct actcctagct gttcatctaa ttccaatggt cccatgctta
     1981 gccgtttcaa tgcggtcact ttctttcctt gggctaagaa catctttttg acttgatgga
     2041 attttccttc ttggatcgtc aataaaaccg tactttggtg cttgtctgct ttgagtattt
     2101 ttaaatcagc cggcttacat tgatacccat cagcgaatac gattccattt tcaaatgctg
     2161 ttacgtctgc cggtgtcacc ctttcgttca caactacttg ataagtcttt gaaacctttt
     2221 tttctggaag tagcatttca tatcccaatt gtccattcga agtgatcagc aatagtcctg
     2281 ttgtatctct atctagtctt cccactggat ataatggttg gaaacgatcg gcacttgcaa
     2341 tcagatcgat tactgtcgtc ttttctggat ctgatacagc tgtaacagct ttttcaggtt
     2401 tattgagaag ataataggac tcatttgttt ctaagtgttc acctgctact tcgatttgat
     2461 gcagtaaact atctacattt cgattttgtc gaaattcgac tgtgccatct atcatcactt
     2521 gcttcaaagc aaacagccgc ttcatttcct tgcgtgtcgt ttctaatttt tcttctatta
     2581 atttatctaa acgcatgctg tttcctttct tattactact aattaattat accttgaata
     2641 ttcttgcttg caaatacatc atcatagtta ttccttgact taattaacag ttcacgttac
     2701 ggttaaatag taaagtgaat tggatttctc atacacagcg taatgacctg gtggagaaaa
     2761 gttgaatcct gactttctaa ggggagatgc gcgcatctct ccttttgcgc ttttttaagc
     2821 gccctgcctt cgatgatgtg cacgagatta gcctttagaa ttcacttaaa taaaatctgt
     2881 ccgttaccaa agcagacagt cacattttaa ggaggaattt tggttatgtc agtatcatta
     2941 gaagtaagta aaagagaagt acgtccccgt tcattaagaa acaaacttcg tcacgaaggg
     3001 aaagttccag ctgttgttta tgggtataaa gtagaaagta cccctatctc attcgatggt
     3061 ttgacactaa gcaaattgtt gcgtgaacat ggagcgaaca cagtcatcac gatggacatc
     3121 gatggacaaa aagtcaatac attggttcac aagatccaaa cgaacacttt taccaatcat
     3181 ttcgaacatg cagaatttct atctgtaaac atgtcggaag aaacagaagt cgaaacagaa
     3241 gtcgttcttg ttggcgaatc agtgggtgct aaatctggtg gagtgttagc tcaaaacttg
     3301 tatacagtag tcgtatctgc tacaccagac aaattgcctg aacgaattga agttgacgtg
     3361 acaaacttgg aattaggtga ttctattaca gtagccgatc ttccaaaaaa cgacgattac
     3421 aaattcgtga ccgacagtga agagcaaatc gctgctgtag tcgctcaaag tgaagaagaa
     3481 agcacaggtg aaggtggcga accagaagtg atcggttcaa cagaagaata atactgaaac
     3541 aatcaggtgg tgttagaagc ggcgggtcag cagcttttaa cacgcctttt ttatttctaa
     3601 tcgtttattt tcatatgggg cttccacttt tgtaaatggc tttacaaacg aaaaatccta
     3661 atttaccaag cttttcctcg catactttta tcgtaccttt ataaaaattt atactttgaa
     3721 aaaaagtatt caattattgt tgcatttttc ctgattcttt attagaatga accctcgttg
     3781 aagtaagtat ttctagttta tcctaggatt aattataaaa ataaaacatt cgttgattcg
     3841 aaggaggtta aacagatgtt tgaaagtttt gatagcagcc gcaaccgtta cgcttcagtt
     3901 ggtgtcgtat caagtttgcc agatgaattg attgacagta tatggtttat tattgaccta
     3961 gatcttaagg gagtcattcc attagaaaat atattaacct ttgatttgat cgaaaatcgt
     4021 ggaaaagtga cgatgcattt ttctcaagca ggaagcaatg tggaaatgga tattgatttg
     4081 ccgtttgcct attcgaacca atttcctgct caagtatacg cctatgatga cggtacgaga
     4141 gaaacgatcc ttttaccaag tgagattaga caatattaag gtgatagata aacgtggatg
     4201 tcccttattt tacagaccag gccaagttgt tgattctttg actcaattct tggcttcttt
     4261 ttatggagtt tcataaatta tcattgattt ctaattggta ttctcaggat aaacgctata
     4321 tactactaac taaattttaa agatataagg agtttaaaag atgcgcgatt taacaaaagg
     4381 aagccccgct aaactgattt tgatgttcac tgttccttta ctgatcggaa atgtttttca
     4441 gcagttctac aatatgatcg atatgatcat cgtgggtcag acgctaggta aaaatgcgct
     4501 ggcagcggtt ggtgcaactg gaagcctgac atttttgatc attggctttg cccaaggttt
     4561 aacagctggt ttagccatta ttaccgcaca acgttacggt gcaaaagatt atcggggtct
     4621 gaagaaaagt tttgctgcta gtgttgtcat tagtcttgtc gtcactgtga ttttaactgt
     4681 cctaagtctc ctgtttattc gtccgatgct tcaattgatg caaactcctc ctgaaatact
     4741 tgatcaagca caaacattta tttcaattat tttattaggg atctttgcat cagtcagttt
     4801 caatttgctt tctaatgtca ttcgcgcact tggtgacagc cgcacaccac tattctttct
     4861 gatcattgcg gtcatcatca acgtcgtact tgatttgatc tttattatct attttggcat
     4921 gggtgtggaa ggtgcagcta ttgctacagt aatcgcacaa gtttcttcca gcgtactgtg
     4981 tctagtgtat atcaagaaaa aaatgccttt gttacagtta cgcaaaaaag atttcaaatt
     5041 tgaaaaagaa gagtttgctg tacacctaaa tgctgctttg ccaatggcgt ttcaatcttc
     5101 gatcatcgct gttggtgcta tcgtgttaca agcagcacta aatagtctag ggacagatgt
     5161 cgtagctgct caagccgctg ctggtcgtat cgaccaattt gcaaatcagc cgatgatgtc
     5221 atttggtatt gcaatggcaa ctttcactgc acaaaactat ggtgcgaaag aatatggccg
     5281 aatcttgcaa ggggtacgtc aaactttact gatgagtgtc ggatttagtc tcttagcagg
     5341 tgctatcgtc attttcttcg gtcatttctt tgttcaattg tttgttagcc catcagaaac
     5401 acgtgtattt gaattagcac aaacctactt caatatcaat gggtctcttt actggatctt
     5461 agcagtcctg ttcattttac gctacacact tcaagggctt ggacaaagca agatccctac
     5521 gatcgccggt atgatggaat tgcttatgcg ttcttttgca gctatcgttc ttacaggaat
     5581 gtggggatac ccaggagcag cagcagcttc tcctttagct tggatcggtt ctgttgccgt
     5641 gttgctttac tcttatatgc gttcgatgaa acaattgaaa cacatgggtg aagaggaaca
     5701 tttcacatta gaacatgcag aagcaagata gccttgatta aaagaaatcg ttgcggctaa
     5761 aaatgaaaac ttttattgaa aatatcttct tcgtttaccg aaaacaggtt ttttagataa
     5821 caaaaaggct gtgacaaaaa atgtcaca
//
LOCUS       DAFBVQ010000105         5770 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.110, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000105 DAFBVQ010000000
VERSION     DAFBVQ010000105.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5770)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5770)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5770
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.110"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            148..1230
                     /locus_tag="LLC22_002687"
     CDS             148..1230
                     /locus_tag="LLC22_002687"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628031.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="M42 family metallopeptidase"
                     /protein_id="HBK5435895.1"
                     /translation="MDTKEEQLLIDLTSAKGVPGNEEEVREVFREYAKPFADDIFYDG
                     LGSVIAKHGAGGGPKVFISGHMDEVGFMVTKITEKGFLEFQTLGGWWGQVMLAQQVEI
                     KTREGKIVHGVIGSKPPHVLTPQVRNKPYEIKDMFIDIGASSQEEAKEWGIRPGDMVT
                     PYIEYKRMNGSKYLLAKAWDNRIGTAVSLRVLENLSKEAHPNVLFAGSDVQEEVGLRG
                     ARTSTHLVNPDIAFALDTGTAGDTPGMTPKEADSILGKGPQILIFDASMIPHKKLLNF
                     VIDVAEEMDIPFQYTVISGGGTDAGQMHLTRDGVPSVAITVPVRYLHSHTSVIHEDDY
                     LNTVKLVTELVKRLDSETVEKIRSYE"
     gene            1230..2033
                     /locus_tag="LLC22_002688"
     CDS             1230..2033
                     /locus_tag="LLC22_002688"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288098.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF975 family protein"
                     /protein_id="HBK5435896.1"
                     /translation="MNNRIPISEYRKKARVSLENQWGINTWLVFLSIIFTSVIQNFFD
                     GFSPFPEESMQQHLLSFLVDNLLLFAFNYALFYIALVVVRGGRPKSNLLFSVFQRKYF
                     GSILGINLINSVINWLLNSLIFLPMFLISGVSTYMQLLFSSNAVPTGVMPEDFLDISF
                     VLSMIGMIFVSALIMSIVGGLFQFAAWTKFDYPDLSVIQCLKYGWFLLKDRIGTYILL
                     QLSFIGWYLLGAIALFIGLLWVIVYVNVSVAEFYEQARIEKGGPDAYFT"
     gene            2103..2843
                     /locus_tag="LLC22_002689"
     CDS             2103..2843
                     /locus_tag="LLC22_002689"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341957.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MBL fold metallo-hydrolase"
                     /protein_id="HBK5435897.1"
                     /translation="MKLTVLGCLGAYPYKNQGTTGYLLQSDGFNLLIDAGSATLIKLQ
                     EHLDPLDLDAVILSHYHHDHIADLGVLQYYWQLHPKRNPETLLSIYGHTKDSIHFEEL
                     TLENVSKGHPYFEAEELKIGPFLITFMETIHPVVCYAMRIVEETTGKVFVFTGDSGYL
                     ESFADFAKDADLFLADTYLFEGNEHHHAHFTSKEAGELAKSANVKKLVLTHLPQFGDL
                     EQLKNEAQKAAGKGIDIELAAVDKVFNI"
     gene            2854..3858
                     /locus_tag="LLC22_002690"
     CDS             2854..3858
                     /locus_tag="LLC22_002690"
                     /EC_number="6.3.1.20"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631995.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="lipoate--protein ligase"
                     /protein_id="HBK5435898.1"
                     /translation="MIFVPNENHDPRINLAIEQYLLQEMPLDEPILLFYINEPSIIIG
                     RNQNTLEEINRDYVEENGIHVVRRLSGGGAVYHDFGNLNFSFIMPDDGDSFRDFAKVT
                     QPIIQALHELGVAGAELKGRNDLVIDGMKFSGNAMYATNGRMFAHGTIMFDSDINEVV
                     NALKVKKDKIESKGIKSIRSRVTNIKPFLPEEKQKMTTEEFRQEILLKIFGVESVEEV
                     KTYELTDEDWKKINRISEEYYRNWDWNYGKSPDFNFSRQKRFSIGSIEVHLNVSEGMI
                     KEAKIFGDFFGLGDISDVEKKLVGQKYDKASLSKIVSQIDVKKYFGAIEPEELLTLLY
                     "
     gene            complement(3903..5747)
                     /locus_tag="LLC22_002691"
     CDS             complement(3903..5747)
                     /locus_tag="LLC22_002691"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631160.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435899.1"
                     /translation="MSFFNNIYNKKESFYLRIKWSIIIILSLLFLTGIAYFFYFIFSP
                     ADSNQMKEIKDSWVFYTKDDPDFKFDSKYTRTIPTVDKDETFIMETTLEKPLDEANLL
                     IKGNHQWITVYLGEKILYQRKDYQEESNPGLSLAVIDLPANYIGKKLTLTVSSPYQNY
                     AGLPPKVYLGTTGPLISFIYSQSVPQVLTMIIAVFIAIGTFFYTIYLMYKQKRLEYSL
                     ILLSCFALALGFEAVSEDILSGILFEPFVHSFLSHLFIILTSAFIICYYWSRMFYYKK
                     WYGIFCTFQLLIFIGVLLYATFTPAELPELMPIANIASVISTLVTSLACIGEAYKNNR
                     FYVACTPWIVLVAIIHCLIYIQTALGIYQTTINWSTILYIIILIVIISYNLIDHILNT
                     DKDRRQVDFLKIKNDLLEQHYEQLRQHIQEVNTLRLEFVQEMENLQDLMHTDQTKAKN
                     YVEKILEEAKNFEMLCSFCNHQVTNLILARYQKLAAKRNIQITFQADLPEELPINDDD
                     LAQLLIHALEHSFRETHAIENPLYRKIYLSIHEQEEHFVICCEHSAHYDTNLFSRGIT
                     EELDDQERFDLMMMKDVADRYTGTLTQEKDTFIDRITVQLSRNYPNPV"
BASE COUNT         1872 a          946 c         1162 g         1790 t
ORIGIN      
        1 aaaataaaga aaacaggcga gtgttgctcg cttgttttct ttatttttga atattctgaa
       61 taaaagataa aaataccaag tttgcctgaa caaaaatcat aagcaatggt ataatcacaa
      121 tatgaatata gaaatggggg aaaacatttg gatacaaaag aagaacagct acttattgat
      181 ttaacttctg caaaaggagt acctggaaat gaagaagagg taagagaagt attcagagaa
      241 tatgccaaac cattcgctga tgatattttt tatgacggtt taggcagtgt gattgccaaa
      301 catggtgctg gcggaggccc caaggtcttt atttctggac atatggacga agttggtttt
      361 atggtaacaa aaataaccga aaaaggattc ttggaattcc aaactcttgg aggttggtgg
      421 gggcaagtca tgcttgctca gcaagttgaa atcaaaacac gtgaagggaa aatcgtccac
      481 ggtgtgattg gttccaaacc accacatgtt ttaacacctc aagtaagaaa taaaccttat
      541 gaaataaagg atatgttcat tgatattggc gcatcaagcc aagaagaagc caaagagtgg
      601 ggcatacgtc ctggagatat ggtcactcca tatattgaat acaaacgaat gaatggcagt
      661 aaatatttac tggcaaaagc atgggataat cgtatcggga cagctgtttc tctgcgagta
      721 ttagagaatc tatctaaaga agcacaccca aatgttttat tcgcaggaag cgatgtgcaa
      781 gaagaagtag gcttgcgagg tgctcgaaca agtacacacc ttgtaaatcc cgatattgct
      841 tttgctttag atactggtac agcaggagac actccaggaa tgacaccaaa agaagcagat
      901 tcgattttag gaaaaggccc acagattttg atttttgatg catctatgat cccgcataaa
      961 aaattattga attttgttat tgatgtagca gaggaaatgg atattccatt ccaatataca
     1021 gtgatttctg gcggaggaac tgatgcagga caaatgcatt tgacaagaga tggtgttccg
     1081 tctgtagcca ttaccgttcc tgttcgttat ctgcattccc atacatcagt gattcatgaa
     1141 gatgattatt tgaatacagt gaaactagtc acagaattag tgaaacggct tgatagtgaa
     1201 acagttgaaa aaattcggag ttatgaataa tgaataatag aatacctatt tctgaatatc
     1261 ggaaaaaagc acgagtttct ttggaaaatc aatggggaat caatacttgg cttgttttct
     1321 tatctataat atttacgagc gtcatccaga acttttttga cggtttcagt ccttttccgg
     1381 aagaaagcat gcagcagcac ttattgagtt ttctagtcga taatttactt ttattcgcat
     1441 tcaactatgc attgttttac attgcgctag tagttgtacg gggtggcaga ccaaaaagta
     1501 accttttatt ttcagttttc caaagaaagt attttggttc gatacttggc atcaatttga
     1561 tcaattcagt catcaactgg ctactcaaca gtttaatctt tctgcccatg tttttaatca
     1621 gcggagtgag tacttatatg cagctgcttt tcagttcaaa tgcggtacct acgggtgtca
     1681 tgccagaaga ttttcttgat atcagctttg ttttatcgat gatagggatg atttttgttt
     1741 cagcactcat catgagtatt gttggcggtt tattccaatt tgctgcatgg acaaagttcg
     1801 actatcctga tttgtcggtt attcaatgtt tgaaatatgg ctggttttta ttgaaagata
     1861 gaattggtac gtatattttg ttgcagctgt cttttatcgg ctggtatttg ctaggagcaa
     1921 tcgctttgtt catcggtctt ttgtgggtca ttgtttatgt gaatgtgtca gttgcagaat
     1981 tttatgaaca agcacggatt gaaaaaggag gtccagacgc ctattttact tagcatgtaa
     2041 gcagtttatt catcaaaaaa ataacttttg tggtaggata aatctttgag ggggaatgta
     2101 cgatgaaatt aactgtttta ggatgcttag gagcgtatcc ttataaaaat caagggacaa
     2161 caggttattt gcttcaatct gacgggttca atttgttgat cgatgcaggt agtgctacgc
     2221 tgatcaaatt acaagaacac cttgatccac ttgatctaga tgctgtgatc cttagccatt
     2281 atcatcatga tcatattgct gaccttggtg tattacagta ttactggcaa cttcatccta
     2341 agagaaatcc ggagacattg ctttcaattt atggacacac aaaagattcc attcactttg
     2401 aagaattgac gttggaaaat gtctcaaaag gacatcctta ttttgaagct gaagaattaa
     2461 aaattggtcc ttttctgatt acttttatgg aaacaatcca tccagtagta tgttacgcca
     2521 tgcgtatcgt agaagaaaca acggggaaag tattcgtatt tacaggtgat tcaggttatt
     2581 tggaaagttt cgctgatttt gcgaaagatg ctgatttgtt tctagcagat acctatcttt
     2641 ttgaaggaaa tgaacatcat catgcccatt tcacttcaaa agaagctgga gaacttgcga
     2701 aatcagctaa cgtaaagaaa cttgtactta cacacctacc tcagtttggt gatttagaac
     2761 aattgaaaaa tgaagcgcaa aaggcagcag gcaaagggat tgatatagaa cttgctgcag
     2821 ttgacaaagt gtttaacatt taggaggaag aacatgattt ttgtaccaaa tgaaaaccac
     2881 gacccaagaa tcaatttagc aattgaacaa tatttgctgc aagaaatgcc tttagatgaa
     2941 cctattttgc tcttttatat caatgaacct tcaatcatca tcggcagaaa ccaaaatacg
     3001 cttgaagaaa tcaatcgaga ttatgtggaa gaaaatggca ttcatgttgt ccgtcgctta
     3061 agtggaggcg gagctgtcta ccatgatttt ggaaacctga actttagttt tatcatgcct
     3121 gatgatgggg attcattccg tgactttgcg aaagtaacac agccaatcat ccaagcactt
     3181 catgaattgg gtgttgctgg ggcggaattg aaaggccgaa atgatctagt cattgatggc
     3241 atgaaatttt ctggcaacgc gatgtatgct accaacggtc ggatgtttgc tcatggaaca
     3301 attatgttcg actctgatat caatgaagta gtcaatgcat taaaagtaaa aaaagacaaa
     3361 atcgaatcaa aaggaatcaa atcgatccgt tctcgtgtaa cgaatatcaa accatttctt
     3421 ccagaagaaa agcaaaaaat gacaacagaa gaatttcgtc aagaaatctt gttgaaaatt
     3481 ttcggcgtag agtcagtaga agaagtaaaa acgtacgaat tgactgatga agattggaaa
     3541 aaaatcaatc gaatctctga ggaatattat cgaaattggg attggaatta cgggaagtct
     3601 ccagatttca atttctctcg ccaaaaacgt ttttctatcg gttcgattga agtccatttg
     3661 aatgtctcag aaggaatgat caaagaagca aaaatctttg gcgatttctt cggactagga
     3721 gatatctctg acgtggaaaa aaaattggtt ggacagaaat atgataaagc atctctatca
     3781 aaaatagtca gccaaattga tgtgaagaaa tattttggtg cgatagaacc agaagaattg
     3841 cttaccttac tttattgaaa ataaaaaata gcggaatcca catatatgga ttccgctatt
     3901 ttttatacag gattcgggta atttcgagag agttgaacag tgatccgatc aatgaaagta
     3961 tctttttcct gcgttagtgt tcctgtgtaa cgatccgcta cgtctttcat catcattaag
     4021 tcaaaacgtt cctgatcatc taattcttct gtgatgcctc gactaaatag gtttgtatcg
     4081 taatgtgcac tatgttcgca acaaatgacg aaatgttcct cttgttcgtg tatcgacaaa
     4141 taaatttttc gatacagtgg attttcgatg gcatgagttt ctctaaagga atgctctaaa
     4201 gcgtggatca aaagttgagc cagatcgtca tcgttgatag gaagttcttc gggaagatct
     4261 gcttggaagg ttatctgaat attccgtttg gcagctaact tctggtaacg cgctaagata
     4321 agatttgtca cctggtggtt gcaaaaagaa cacagcattt cgaaattttt tgcttcttct
     4381 aatatctttt ccacatagtt tttagctttt gtttggtccg tatgcattaa atcttgcaga
     4441 ttctccatct cttggacaaa ttccaggcga agtgtattta cttcttggat atgctgtcga
     4501 agctgctcat aatgttgctc caacaaatca tttttgattt ttaagaaatc tacttgtctc
     4561 cgatctttgt cggtatttaa gatgtgatcg attagattgt agctgataat aacgattaga
     4621 atgataatat ataaaatcgt agaccaattg atcgttgttt gatagatacc taatgccgtt
     4681 tggatgtaaa tcaagcaatg gataatggct accaagacga tccaaggtgt acaagctaca
     4741 taaaaacggt tattcttata tgcttcgcca atgcatgcaa gtgaagtgac taaagtgctt
     4801 ataacactag caatattagc aatcggcatt aattcaggaa gttctgcagg agtaaaagtt
     4861 gcataaagca gaacgccgat aaaaatcaaa agttggaacg tacaaaaaat tccgtaccat
     4921 tttttatagt aaaacattcg gctccaatag tagcagatga tgaaagctga cgttaagata
     4981 ataaataaat gagataaaaa agaatgaacg aatggttcaa aaagaatacc acttaaaata
     5041 tcttctgata cagcttcaaa tcctaatgcc aaagcaaagc aacttaagag aataagtgag
     5101 tattcaagac gtttttgttt atacatcaag tagatcgtat agaaaaaggt ccctatagcg
     5161 ataaaaacag cgattatcat cgtcaatact tgcggcactg attgtgaata aataaaacta
     5221 atcaatggtc cagttgttcc tagataaact ttcggtggca gtccagcata gttctgataa
     5281 ggagatgaga ctgtaagggt caattttttt ccgatataat ttgctggtaa atctatcaca
     5341 gccaatgaga gtccgggatt gctttcttcc tgataatctt tccgttggta taaaatcttt
     5401 tcgcctagat atacagtaat ccattgatgg tttcctttga ttagtaaatt tgcttcgtcc
     5461 aacggttttt caagtgtcgt ttccataatg aatgtttcgt ctttatccac ggtaggaatc
     5521 gtacgagtgt acttgctgtc aaacttaaaa tcaggatcat cttttgtata gaaaacccac
     5581 gaatctttta tttctttcat ttgattgctg tccgcaggag aaaaaataaa ataaaagaaa
     5641 taagcaattc ctgttaaaaa taacaatgat aatataatga ttatgctcca ctttatacgt
     5701 aaataaaaag attctttttt attatatatg ttattaaaaa aagacataaa ggtattcctt
     5761 tctaaaactt
//
LOCUS       DAFBVQ010000106         5720 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.111, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000106 DAFBVQ010000000
VERSION     DAFBVQ010000106.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5720)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5720)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5720
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.111"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            57..596
                     /locus_tag="LLC22_002692"
     CDS             57..596
                     /locus_tag="LLC22_002692"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="topology modulation protein"
                     /protein_id="HBK5435900.1"
                     /translation="MKIIVIGQSGSGKSTLARKIKEITDFPLLPLDLLWHTTDYSIQA
                     KKWFLQEQQSFMVSNPSWIVEGNYTSTLEERIKEADKIIWLKVPRYLAIYRVVWRSLK
                     RKINKKSRPDMPESFSEKLNREYLEFLSFIWHFEENNEPKIQQLIQVANARNKLIILK
                     TRREKQEFLTKLKIESKNN"
     gene            670..1110
                     /locus_tag="LLC22_002693"
     CDS             670..1110
                     /locus_tag="LLC22_002693"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CopY/TcrY family copper transport repressor"
                     /protein_id="HBK5435901.1"
                     /translation="MEKVKTPVKISDSEWEIMRVIWTLGQTTAQEITQILADSMDWKP
                     ATIKTLLGRLVKKEVIWTEQEGKKFIYHPAVSEMETVRSATENLFSHICAKRIGETIA
                     DLVEEATLTQEDINEILKQLEQKQPVDTIECNCIPGQCECKQHQ"
     gene            1123..1332
                     /gene="copZ"
                     /locus_tag="LLC22_002694"
     CDS             1123..1332
                     /gene="copZ"
                     /locus_tag="LLC22_002694"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper chaperone CopZ"
                     /protein_id="HBK5435902.1"
                     /translation="MKQQFSIEGMSCNHCAARVEETVSALDGVQKVKVNLKKANGTVK
                     FDETKVQSEKICQAINGLGYKAEVI"
     gene            1332..3518
                     /locus_tag="LLC22_002695"
     CDS             1332..3518
                     /locus_tag="LLC22_002695"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737925.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper-translocating P-type ATPase"
                     /protein_id="HBK5435903.1"
                     /translation="MATAETKMDTFVITGMTCANCSARIEKELNGQPGVVNATVNLAT
                     EKASVKYEGTTTEKLIQSVENIGYGAILYDEAHKQKIAEEKQAYLKKMLFDLILSTVL
                     TLPLMLSMIAMMLGSHAAIVHFFHFPIVQLVLSAPVQFYVGARFYKGAYHAIKTKAPN
                     MDVLVAIGTSAAFALSIYNGFFRGHPQDLYFESSSMIITLILLGKYLEHTAKTKTGNA
                     IKQLMSLQTKTAQVIRNGKEETLAIEEVVVGDQLVIRPGEQIPADGRIISGSSAIDES
                     MLTGENLPVEKNPDDTLFGGTINTNGLLHMEVTQVGKQTVLAQIIQMVEDAQGSKAPI
                     QKIADRISGIFVPIVLVIAFITLIATGLITGDWQLALIHSVSVLVIACPCALGLATPT
                     AIMVGTGVGARNGILIKGGEALEAAAHLDSIVLDKTGTITEGKPKVTDLVGSKEVLSI
                     FYTLEQASEHPLGKAIVEYGKLQEAATYDMIDFTAHPGAGISGTINGVRYFAGTRKRL
                     IELNLSFDEYQEHALELEQQGKTVMFLADEKQVIGWIAVADQIKLEAKQAIKQLQNKG
                     LDVFMLTGDNKLAAETIGKQVGIDPKHIFAEVLPEDKAAYVEKLQKDGKKVGMAGDGI
                     NDAPALALADVGMAMGSGTDIAMETADVTLMNSSLASIAQTIELSRLTLRKIKQNLFW
                     AFVYNTIGIPFAALGFLNPIIAGGAMAFSSVSVLLNSLSLNRHMKK"
     gene            3538..5709
                     /gene="copB"
                     /locus_tag="LLC22_002696"
     CDS             3538..5709
                     /gene="copB"
                     /locus_tag="LLC22_002696"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376511.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="copper/silver-translocating P-type ATPase CopB"
                     /protein_id="HBK5435904.1"
                     /translation="MNGNDMEKKHEHKKEVVNKESTESHEKQMEMKHDHSQMDHSMHM
                     GHNHGDIANSKQMDHSMHMDHEHGGMDHSMHMGNFKQKFWLSLILAIPIILFSPMMGM
                     EFPFQVTFPGSDWLVLILATILFIYGGQPFLSGAKMELKQKSPAMMTLIAMGITVAYI
                     YSVYSFIANLLNPHTHVMDFFWELATLIVIMLLGHWIEMNAVSNASNALQKLAELLPE
                     SVKRLTKDGKEETVSLKEVNEGDRLIVRSGDKMPTDGVILKGETIVDESAVTGESRGI
                     KKQANDKVIGGSINGDGTIEIEVTGTGENGYLAKVMEMVRKAQGEKSKLESLSDKVAK
                     WLFYVALIVGILAFIAWLFLTDLPNALERMVTVFIIACPHALGLAIPLVVARSTSIAA
                     KNGLLLKNRNALEQANDLDVIMLDKTGTLTEGKFTVTGVEVLDDAFNKNEILQYLGAL
                     EANANHPLAVGIMNYLKEHEIKPYQAENLKNLSGVGLEATVKKQQVKIVNEKEVERLG
                     LNVEQALLKPYQEQGNTISFLILENHLAAIVALGDVVKTEAKEFIRTLKERKITPVML
                     TGDNKNAAQAVADYLGIEEYYGGLLPDDKEAVVQKYLDQGKKVIMVGDGINDAPSLAR
                     ASIGMAIGAGTDIAIDSADVVLTNSDPKDILHFLDLAKQTRKKMIQNLWWGAGYNILA
                     IPLAAGILAPIGIILSPAVGAVLMSLSTVVVALNALTLKIK"
BASE COUNT         1966 a         1001 c         1290 g         1463 t
ORIGIN      
        1 gcggcgttat aagtggtatg atcgaaccaa attccaaaga gaagtgaggg agaagaatga
       61 agatcatcgt gattggacaa agtgggtcgg gaaaatcgac cctcgcaagg aagatcaaag
      121 aaatcaccga ctttccgcta ctgccgctag accttttatg gcatacaaca gactacagta
      181 ttcaggcaaa aaagtggttt ttgcaagaac agcaatcgtt tatggtatct aatccgtcat
      241 ggattgttga aggaaattat acttctacat tagaggaaag gattaaagaa gcagataaga
      301 tcatttggct taaagtgccg cgttatctcg ccatctaccg agtagtttgg cgttctctaa
      361 aaagaaagat aaacaaaaaa tctcggccag atatgcctga atcattttca gagaaactaa
      421 acagggaata cttagaattt ttatctttta tctggcattt tgaagaaaac aatgaaccga
      481 aaatacagca gctgatccaa gtagctaatg caagaaataa actgatcatc cttaaaacaa
      541 gacgagagaa acaagaattt ttaactaaat tgaaaataga gagcaaaaat aattgacagt
      601 ttttgtttac aagcgtaatc tgtattcata agctaatgat tacatttgta aacgaaaggt
      661 gtgaaataaa tggaaaaagt caaaacgcca gtaaagatca gtgattcaga gtgggagatc
      721 atgcgtgtta tttggacact tggacagacg acagcccaag aaatcacgca gatcttagct
      781 gattcgatgg attggaaacc agcaacgatc aaaactttgc tgggacgttt ggtaaaaaaa
      841 gaagtgatct ggacagaaca agaaggaaaa aaattcattt atcatccagc tgtctcggag
      901 atggaaacag ttcgcagtgc gacggaaaat cttttttccc atatctgtgc aaaaaggatt
      961 ggagagacga ttgcggatct agtagaagaa gccactttga ctcaagaaga tatcaatgag
     1021 attttgaaac aactggaaca aaagcaacca gtagatacga tcgaatgtaa ctgtatccca
     1081 ggtcaatgtg aatgtaaaca acatcaatag gaggaagaaa aaatgaaaca acaattttca
     1141 atcgaaggta tgagctgcaa tcattgtgca gcaagagtag aagaaacagt aagcgcactt
     1201 gacggcgtgc aaaaagtgaa agtaaatttg aaaaaagcaa acggtacggt caagtttgat
     1261 gaaacaaaag ttcaatccga aaagatttgt caagcaatca atggattggg ttataaagca
     1321 gaggtgattt gatggcaaca gcagaaacca aaatggatac gttcgtcatt acaggtatga
     1381 cttgtgcaaa ttgttctgct aggatcgaaa aagagctgaa cggacaacct ggtgtggtca
     1441 atgccacagt caacttggcc actgaaaaag caagtgtcaa atatgaaggg acgaccactg
     1501 aaaaattaat ccaaagcgta gaaaacatcg gttatggtgc aattttgtac gatgaagccc
     1561 acaaacaaaa aattgcagaa gaaaagcaag cgtatttgaa aaaaatgcta ttcgatctta
     1621 tattgagtac ggttttgact ttgccgttga tgttgtcaat gattgctatg atgttaggaa
     1681 gccatgcggc gattgttcac ttttttcatt ttccaatcgt ccagttagtg ctgtctgctc
     1741 ctgtccaatt ttatgtcggt gctcgttttt ataaaggtgc gtaccatgca atcaagacga
     1801 aagcaccaaa tatggatgta ttggtagcaa ttggaacatc ggctgccttt gcattgagca
     1861 tttacaacgg atttttccgt ggacaccccc aagatcttta ttttgaaagc agcagtatga
     1921 tcatcacgct gattttgctc ggcaaatatt tggaacatac agcaaaaacg aaaacaggta
     1981 atgcaatcaa acaattgatg tctcttcaaa caaaaaccgc ccaagtgata agaaacggga
     2041 aagaagaaac gttagcgatt gaagaagtag tcgttggtga tcaactagtc atccgtcctg
     2101 gtgagcagat tccagcagat ggtcgaatta tttcaggaag cagtgcgata gatgaaagta
     2161 tgcttactgg tgaaaatctt cctgtagaaa agaatccgga tgacacgctt tttggcggga
     2221 caatcaatac gaatggtctg ctacacatgg aagtcacaca agtcggcaag cagacagtat
     2281 tagcgcaaat cattcaaatg gtggaagatg ctcaagggag caaagcccca atccaaaaaa
     2341 tcgcagatcg gatctcaggg atttttgttc cgatcgtatt agtcatcgcg tttatcacgc
     2401 tcatagctac aggtttgatc actggtgatt ggcaactcgc attgatccat agtgtctctg
     2461 tattagtcat tgcgtgtcca tgtgcattag gtttagcgac cccaacagct attatggtag
     2521 gaacgggtgt tggtgcacga aatggaattt taattaaagg cggagaagca ttagaagcag
     2581 ctgctcactt agacagcatt gttttggata aaactggaac gattacagaa ggaaagccca
     2641 aagttacaga tctagtcggt tcaaaagaag tcctatctat tttttatact ttagaacaag
     2701 cttctgaaca tccactaggt aaagcaatcg tggaatacgg aaaactgcaa gaagcagcaa
     2761 catacgatat gattgatttt acagcccacc caggtgctgg gatcagcggt acgattaatg
     2821 gagtacgcta ttttgcgggt acacgtaaac gattaattga attgaaccta tcatttgatg
     2881 aataccaaga acacgcgtta gaattagaac agcagggaaa aacagtcatg tttttagctg
     2941 atgaaaagca agtgatcggg tggattgccg tggctgatca aatcaaacta gaagccaaac
     3001 aagcaatcaa gcagctccag aataaaggat tagatgtttt tatgctgaca ggagacaaca
     3061 aactggcagc cgaaacgatt ggtaaacaag ttggtattga tccaaagcat atctttgctg
     3121 aagtacttcc agaggataaa gcagcctacg tagaaaaact tcagaaagat ggcaaaaaag
     3181 tcggtatggc aggcgatgga atcaatgatg caccggcctt agcattagct gatgtcggta
     3241 tggcaatggg aagtggaacg gacattgcga tggaaacagc cgatgtgacg ctgatgaata
     3301 gcagtttggc atccattgca caaacaatcg agttgtctag gttgacattg agaaaaatca
     3361 aacaaaatct tttctgggct tttgtctata atacgattgg tattcctttt gccgcactag
     3421 gctttttgaa tccaatcatt gcaggaggag cgatggcgtt tagttccgtc agtgtattgt
     3481 tgaactccct gagcttaaat cgacacatga aaaagtaaga gaagggatgg agtaaaaatg
     3541 aatgggaacg atatggagaa aaaacatgag cataaaaaag aagtagtaaa caaagaaagt
     3601 acagaatctc atgaaaaaca gatggagatg aaacatgacc atagtcagat ggatcattcc
     3661 atgcacatgg gacataacca tggagatata gcaaacagca aacaaatgga ccattcgatg
     3721 cacatggatc acgaacacgg cggcatggat cattccatgc acatggggaa tttcaaacaa
     3781 aaattttggc tatcgcttat cctagctatc ccaatcattc ttttttcacc aatgatggga
     3841 atggaatttc catttcaagt aacgtttcct ggttctgatt ggctcgtatt gatcttagca
     3901 actatactat ttatctatgg cggtcagcca tttttaagtg gagctaagat ggaattgaaa
     3961 caaaaaagtc ctgctatgat gacactgatc gcgatgggga ttacagttgc atatatttat
     4021 agtgtctatt cgtttatcgc aaatctgctc aatccacata cacacgtcat ggatttcttc
     4081 tgggaattgg ctactttgat cgttattatg ctactaggtc actggattga aatgaatgct
     4141 gtgtcgaatg ccagcaatgc tttacaaaaa ctagcagaat tactgccaga atcagtgaaa
     4201 cgcttgacga aagatggaaa agaagagaca gtttcattga aagaagtaaa cgaaggtgat
     4261 cgtttgatcg tccggtctgg tgataaaatg ccaacagatg gtgtaatctt gaaaggtgaa
     4321 acaattgttg acgaatcagc tgtgactggc gaatcaagag gaatcaaaaa acaagccaat
     4381 gacaaagtga ttggcggttc tatcaatggg gatggaacga tcgaaatcga agtaactgga
     4441 actggtgaaa atggttatct agcgaaggtt atggaaatgg tgcgaaaagc acaaggagaa
     4501 aaatccaagc tagagtcatt atctgacaaa gtggcaaaat ggctgtttta tgtcgcatta
     4561 attgtgggta tcctggcatt catcgcctgg ttgttcttga cagatcttcc taatgcatta
     4621 gaacgtatgg taacagtctt tatcatcgcc tgtcctcatg ctctaggttt agctatccca
     4681 ttagttgttg ctcgctccac atcaatagca gctaaaaacg gattactttt gaaaaaccgc
     4741 aatgcactgg agcaagccaa tgatctagat gtgatcatgc tggacaaaac aggaacacta
     4801 acagaaggaa aatttactgt aacgggtgtc gaagtacttg atgatgcgtt caataaaaat
     4861 gaaatccttc aatatctagg agccttggaa gcgaatgcca atcatccatt ggctgttggc
     4921 attatgaatt atttgaaaga acatgaaatc aagccttatc aagctgaaaa tctaaaaaat
     4981 ctttcaggag tcgggctaga ggcaacagtc aaaaaacaac aagtgaaaat agttaatgaa
     5041 aaagaagttg agcgtctcgg attaaacgta gaacaagcat tattgaaacc ttaccaagaa
     5101 caaggaaata ccatcagctt cctgatttta gaaaatcatc tagctgcaat cgttgcttta
     5161 ggtgacgtag taaaaacaga agcaaaagaa tttatccgaa cattgaaaga aagaaaaatc
     5221 actcctgtca tgcttactgg tgacaataaa aacgctgccc aagcagtagc agattattta
     5281 gggatcgaag aatattatgg cggtttatta ccagatgata aagaagctgt tgtccagaaa
     5341 taccttgacc aagggaaaaa agtaatcatg gtgggtgatg ggatcaatga tgcgccaagt
     5401 ttagcccgtg cttcaatcgg gatggcaatc ggtgcaggga cagatatcgc aatcgattct
     5461 gcggatgtcg tattgacaaa cagcgatcca aaagatattt tgcattttct tgatctagcc
     5521 aagcaaacgc gaaagaaaat gatccagaac ctctggtggg gggcaggtta caatattctt
     5581 gcaattccgc tagcagccgg aattcttgcg ccaattggta tcatattaag tccagcagtt
     5641 ggtgctgtct tgatgtcgtt aagtacggta gttgtagctc taaatgcttt gacattgaaa
     5701 atcaaataat aatgaaaaaa
//
LOCUS       DAFBVQ010000107         5501 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.112, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000107 DAFBVQ010000000
VERSION     DAFBVQ010000107.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5501)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5501)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5501
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.112"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            153..1142
                     /locus_tag="LLC22_002697"
     CDS             153..1142
                     /locus_tag="LLC22_002697"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312605.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SIS domain-containing protein"
                     /protein_id="HBK5435905.1"
                     /translation="MRDKEMRQLHKEQIETAMAALKEKTIDHVYFTACGGSQAVLMAG
                     QYLFDKELTVPCHVYTANEFNYAIPKGLSENSLVITCSHSGTTPETVEATKKAREFGA
                     MTICLSNEEGSPLWEAAEYPVHYDWGKDVDASDLNKGILYGLLFNILLVLDGSKKWET
                     CLNEFDKLNDLVIAEKSKFEITAKEWGKNQKRDKIIYTIGSGINYGEIYSTAACWFME
                     MQWINSNAIHSGEFFHGPFEITDYDVPFILVKSIGDTRFLDQRVEDFTKKFSNKLMVL
                     DQADFDLESIDSVAKEYIAAVLSGVVIRQMVEAIAFERGHSLDVRRYMWQMKY"
     gene            1124..1585
                     /locus_tag="LLC22_002698"
     CDS             1124..1585
                     /locus_tag="LLC22_002698"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312606.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS fructose transporter subunit IIA"
                     /protein_id="HBK5435906.1"
                     /translation="MANEILINRRLQKMANQLFHIVITTHSTLCEGYLKATKLILMND
                     ATGISAVPFKENTSPDDFEESMKEIISQHHLQPLIILTDLIGGTPNNVSIKQLNNNRI
                     QIIAGINLPLLLELLMAQSAGKSIEEIDFKELLNNSQKSMVHINSLLKDVS"
     gene            1635..2099
                     /locus_tag="LLC22_002699"
     CDS             1635..2099
                     /locus_tag="LLC22_002699"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337413.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIB"
                     /protein_id="HBK5435907.1"
                     /translation="MIKLVRVDHRLLHGQVIFSWTKQYDINHIIVADNKVPGDPMSVM
                     ALTIAKPADCKLDIVKISDVKGIMETSPNDNYMILIKGPKEAFELVQNLPEIKEINFG
                     GVSKKSESKQYGKAVFLTPEELEATKKILDQEVKIFVQQVPSSSIENVDFSK"
     gene            2113..2862
                     /locus_tag="LLC22_002700"
     CDS             2113..2862
                     /locus_tag="LLC22_002700"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS sugar transporter subunit IIC"
                     /protein_id="HBK5435908.1"
                     /translation="MLLKAILLGLVGVVAVIDSRLIGRQNIGRPLILSTLAGLVLGDL
                     HTGIVLGASLELISMGFVSIGAAGPPNMQLGSIIATAFAILTNSSTETALTIAIPVAV
                     AGEFMSIIMRMIIAQFGHAADKAIENNKFRKAQIIHIYWSFIFNAFVYFIPIFLTVYF
                     GADVVADLVDKIPEMITDALTVSGNMLSALGFAMLLSTMLSKKLYPYFIFGFFIVAYS
                     GLSLIGVTIFAALIAFVMDQVKYGKREEAHG"
     gene            2862..3692
                     /locus_tag="LLC22_002701"
     CDS             2862..3692
                     /locus_tag="LLC22_002701"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341860.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS system mannose/fructose/sorbose family
                     transporter subunit IID"
                     /protein_id="HBK5435909.1"
                     /translation="MENSTEKKRLITKKDLHKMCLRSWTIMCSWNYERQMHMGFMYGM
                     APILNKVYKNDEEKKREAYTRHMAFFNCTPQMTPFIMGLCASMEEQNAQAEEGNFNTE
                     SISMIKTSLMGPFAGIGDSFFQGTLRIITFGIGLSFAKQGSILGPILAVGLFAIPSIL
                     AVFYGGKLGYESGNKYLTKLYQEGLMDRVMQFASIIGLAVVGGMVASMVPIVTPLKFT
                     TGGTELVLQDLLDSIIPGLLPLVCTLGIYKLIKKNVSTNMLLLGCILAGFVLSIIGIL
                     "
     gene            3692..4339
                     /locus_tag="LLC22_002702"
     CDS             3692..4339
                     /locus_tag="LLC22_002702"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341861.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family phosphatase"
                     /protein_id="HBK5435910.1"
                     /translation="MIKALIFDMDGVLIDSEIMYQKWVFNFLKQENLSYPLYSYQKKI
                     GTTASIFDDIEKYNEGCNSLELKGKFTKYWKSQKIDYLDIFPNILIEQLEWLKKKKIK
                     MAIASSSPMDTINEVVTTCKIESYFDCLISGRDLPESKPNPTIFLKASEQLRIPVEEC
                     LVIEDSYNGIKAGKRANMKVLAIKDKRFSQDVSLADDVIYDIKYLRQEVQVKFGI"
     gene            complement(4437..5213)
                     /locus_tag="LLC22_002703"
     CDS             complement(4437..5213)
                     /locus_tag="LLC22_002703"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GntR family transcriptional regulator"
                     /protein_id="HBK5435911.1"
                     /translation="MNFQDNRPLYLQVEASIRNDIREKKYLPGEQLPTEEELCKIYGV
                     SKITIRKAFKLLTESGTVERLRGKGTFVTQKKESLKLAGVHGFSDSLSTRGHKIRYTV
                     LHSKIIKADEFLANKLQINVTDRVYNIKRLMWEDGAPMGIDNFFASEEKFPTLFEKGS
                     QYTSLYKLLEDDYDVKATSSIMEINGLSATPELSDLLQCIVGDPLFILEKVGKDKNNQ
                     PFHYSQSTVRCDRISYVIEVTENITLDTVHKNDSDPKVID"
     gene            5295..5438
                     /locus_tag="LLC22_002704"
                     /pseudo
     CDS             5295..5438
                     /locus_tag="LLC22_002704"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016608918.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="RNA-binding protein"
BASE COUNT         1882 a          747 c          979 g         1893 t
ORIGIN      
        1 atcatccata aaatggactt tgtctacagt ctggcatttt attatataaa attgttataa
       61 aaaatttttt ttgaaaaata gtattgcaaa ataaagcaat ttcatagata ataggtatcg
      121 taaagttata taactttata atacctatta gagtgaggga taaagaaatg agacaactac
      181 acaaagaaca gattgaaaca gcaatggcag cgttaaagga aaagacaatt gatcatgtat
      241 attttacagc atgtgggggt tcacaagccg ttttaatggc tggtcaatat ctatttgata
      301 aagaattaac tgtaccttgt catgtttata ctgctaacga atttaactat gctataccaa
      361 aaggattatc tgaaaattct ttagttatca cttgttccca ttctggcaca acaccagaaa
      421 ctgtagaagc aacaaaaaaa gcaagagaat ttggagcaat gactatttgt ttatctaatg
      481 aagaaggatc tcctctatgg gaagcagctg aatatcctgt tcactatgat tggggtaaag
      541 atgttgatgc tagtgattta aataaaggaa ttctttatgg tttattattt aatattttac
      601 ttgttttaga tggctctaaa aaatgggaaa cttgcttgaa tgaatttgat aagttaaatg
      661 atcttgttat tgctgaaaag agcaaatttg aaataactgc taaagaatgg ggtaaaaacc
      721 aaaaacgaga taaaattatt tacacaattg gtagcggtat taattacgga gaaatttact
      781 ccacagcagc ttgctggttc atggaaatgc aatggattaa ttctaatgct attcattctg
      841 gggaattttt ccatggtcct tttgaaatca ctgattatga tgtaccattc atcttagtga
      901 aaagtattgg agatacaaga tttttagatc aacgggtaga agacttcact aaaaaattca
      961 gtaataaatt aatggtttta gaccaagctg attttgactt agaatctata gatagtgtag
     1021 cgaaagaata tattgcagct gtacttagtg gcgttgttat tcgccaaatg gtagaagcga
     1081 ttgcttttga aagaggccat tccttagatg ttagacgcta tatgtggcaa atgaaatatt
     1141 aattaatagg aggttgcaaa agatggcaaa tcaattattt cacattgtga ttacaacaca
     1201 ttctaccctt tgtgagggtt atttaaaggc aacaaaatta attttaatga atgacgccac
     1261 aggtattagt gctgttccat ttaaagaaaa tactagtcca gatgattttg aggagagtat
     1321 gaaagaaata attagtcagc atcatttgca acctctaatt attttaacgg atttaattgg
     1381 aggaacacct aataatgttt ctattaaaca gttgaacaac aatagaattc aaattattgc
     1441 tgggattaat ttacctcttt tactggagtt attaatggcc cagtcagctg gtaaatctat
     1501 agaagaaata gattttaagg aattactgaa taactctcaa aaaagtatgg ttcatattaa
     1561 ttcgctttta aaagatgtca gttaaggtgg caatttctat tctataaatt ttaaaaattg
     1621 aaggaggaaa tagaatgatt aaattagtgc gtgtagacca cagattactt catggacaag
     1681 taatattttc ttggactaaa cagtatgata ttaaccatat tattgtggct gataacaaag
     1741 ttccaggaga tccaatgtct gtgatggctt tgacaattgc taaacctgct gattgcaaat
     1801 tagacattgt taaaattagt gatgttaaag ggattatgga aacatcccca aatgataatt
     1861 acatgatttt aattaaagga cctaaggaag cttttgaatt agttcaaaat ttaccagaaa
     1921 ttaaagaaat taattttggc ggtgtgtcta agaaaagcga gtccaaacaa tatggaaagg
     1981 cagtcttttt aactcctgaa gaattagaag ccacaaaaaa aattcttgat caagaagtga
     2041 aaatatttgt gcaacaagtc ccatcttcaa gtattgaaaa tgtagatttt agtaagtaag
     2101 gggggaaaat aaatgttatt aaaagccatt ttattaggtt tagttggtgt ggtagctgtt
     2161 attgactcca ggttaattgg tcgacaaaat attggtagac cactaatttt gagtacactt
     2221 gccggacttg tgctaggtga cttgcataca gggattgttc ttggggcatc tttagaatta
     2281 atttctatgg gattcgtctc aattggggcg gctggacctc ctaatatgca acttggtagt
     2341 attattgcca ctgcttttgc aattttaact aatagtagta cagaaacagc cttaacaata
     2401 gctatcccag tggctgtagc tggtgaattt atgagtatta tcatgcgtat gataattgct
     2461 caatttggac atgctgcaga taaagccatt gaaaataata aatttagaaa agctcaaatt
     2521 attcatattt attggtcatt tatttttaat gcttttgttt actttattcc aatcttttta
     2581 acagtatatt ttggtgctga cgttgtggca gatttagtag ataaaattcc agaaatgatt
     2641 acagacgcct tgactgtctc tggaaatatg ctttccgcat tagggtttgc aatgctatta
     2701 agcacaatgt tgagtaaaaa attatatcct tactttattt ttggattctt tattgttgcc
     2761 tattcaggtc tttcactaat tggcgtgaca atttttgcag ctctgattgc ctttgtaatg
     2821 gatcaagtta aatatggaaa aagagaagag gcgcatggtt aatggaaaat agtacagaaa
     2881 aaaaacgttt aatcacaaaa aaagatcttc ataagatgtg tcttcgttca tggacaatca
     2941 tgtgttcgtg gaattatgaa agacaaatgc atatgggatt tatgtatggg atggcgccaa
     3001 ttttaaataa agtttataaa aatgatgaag agaaaaaaag agaagcttat actcgtcata
     3061 tggcattttt taactgtacg cctcaaatga ctccatttat tatgggactt tgtgcttcta
     3121 tggaagaaca aaatgctcaa gcagaagaag gaaactttaa tactgaatct atctccatga
     3181 ttaaaaccag tttaatgggt ccttttgctg gaattggtga ttcatttttc caaggtactt
     3241 taagaattat tacatttggg attggattgt cttttgctaa gcaaggtagt attttaggac
     3301 cgattttagc tgttggcctt tttgctatac cttctatttt agctgttttt tacggcggta
     3361 aattaggata tgagtctggc aataaatacc ttactaaatt gtatcaagaa ggtcttatgg
     3421 atcgagtaat gcaatttgct tctatcattg gtttggctgt agtaggtgga atggtggcta
     3481 gcatggtgcc aattgtcacc cctttaaaat tcactacagg gggaacagaa cttgttttac
     3541 aagacttact tgattccatt attcctggat tattaccact tgtatgtact ttgggaatat
     3601 ataaattgat taagaaaaat gttagtacaa atatgctctt attaggttgt attttggcag
     3661 ggtttgtttt aagtataata ggtatcttat aatgattaag gctctaattt ttgatatgga
     3721 cggagtttta attgatagcg agattatgta tcaaaagtgg gtatttaatt ttttaaaaca
     3781 agaaaattta agctatcctt tgtattctta tcaaaaaaag attggaacta cagcaagtat
     3841 ttttgatgat atagaaaagt acaatgaggg atgtaacagt ttagaattga agggaaaatt
     3901 tactaaatat tggaaatcgc aaaagattga ttacttggat atttttccta atatactaat
     3961 tgaacagctt gaatggttaa aaaagaaaaa aataaaaatg gcaattgctt cttccagtcc
     4021 aatggatact ataaatgaag ttgttaccac ttgtaaaata gagtcatatt ttgattgttt
     4081 aattagcgga agagatttgc cagaaagtaa acctaatcct actatattcc ttaaagcttc
     4141 agaacagctc agaattccag ttgaagaatg tctggtgata gaagattctt ataatggtat
     4201 aaaagctggt aaaagagcaa atatgaaggt tcttgcaatt aaagataaac gtttttctca
     4261 agatgtaagt ctagcagatg atgttattta cgatattaaa tatctgcgac aagaagtaca
     4321 ggtgaaattt ggaatataaa taagtttttt gatgtattta gagaatatta gtaaaaataa
     4381 aaatcatgcc caaatctaat caaaattgat tgctttgggt atgatttctt ttaatatcaa
     4441 tctattactt taggatctga atcattttta tgcaccgtat ctaaagtgat attttctgtg
     4501 acttcaataa cataactaat tctatcacaa cgaactgtgg attgagaata atgaaatggt
     4561 tgattatttt tatctttgcc aaccttttct aaaataaata gcggatctcc tactatacat
     4621 tgcaataagt cggaaagctc aggtgttgca gataaaccgt ttatttccat aatagagctc
     4681 gtagctttga catcatagtc atcttctaga agtttatata atgaagtata ttggctacct
     4741 ttttcaaata aagttggaaa tttttcttct gatgcgaaaa aattatcaat tcccatcggg
     4801 gcaccgtctt cccacattaa acgtttaata ttgtaaactc tatcagttac attgatttgt
     4861 aatttattag ctaaaaactc atcagccttt ataattttag aatgtaaaac agtatatcta
     4921 attttatgtc ctcgggtaga aagagaatcg ctaaatccat gaactccagc taattttaaa
     4981 ctttcttttt tttgagttac aaaggtccct ttccccctta atcgttcaac tgttccactt
     5041 tctgttaaaa gtttaaaagc ttttcgaatg gtaatcttac ttactccata aattttacat
     5101 aattcttctt ctgtaggtaa ttgctctcct ggaagatatt ttttttcacg aatatcgtta
     5161 cgtatagaag cttctacttg tagatataat ggtctattat cttgaaaatt catagtacac
     5221 tccctaaaaa gttatacttc attatatcac aatttattaa aataaaagat taagatataa
     5281 atataaatga actagtcttt gactaaccaa tgcccgcttt tgaaagaaaa caaattcatt
     5341 ctgttttaag taaaaatcct tatgttacca ctcattctga aggggatgag ccttatcgct
     5401 acttggttgt ggaaccaagc gataagacaa ttttataaat tcaatattaa ttaaaataaa
     5461 aacaaacaaa gtagattatt ttactttgtt tgttttttta t
//
LOCUS       DAFBVQ010000108         5339 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.113, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000108 DAFBVQ010000000
VERSION     DAFBVQ010000108.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5339)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5339)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5339
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.113"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(62..280)
                     /locus_tag="LLC22_002705"
                     /pseudo
     CDS             complement(62..280)
                     /locus_tag="LLC22_002705"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002391850.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
     gene            complement(546..740)
                     /locus_tag="LLC22_002706"
     CDS             complement(546..740)
                     /locus_tag="LLC22_002706"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435912.1"
                     /translation="MMGFFLRFYIIELTGRLTVFFGNFAIKPFAEVTAHYICKWLDCK
                     NKIKKVFHYISSSPCQIRPG"
     gene            complement(840..926)
                     /locus_tag="LLC22_002707"
                     /pseudo
     CDS             complement(840..926)
                     /locus_tag="LLC22_002707"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339775.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
     gene            2092..3132
                     /locus_tag="LLC22_002708"
     CDS             2092..3132
                     /locus_tag="LLC22_002708"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002310953.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBK5435913.1"
                     /translation="MTDFKFFKADRVYNELFYQFPKVFIVSDEYKKMKDSTKIAYMLL
                     KARLEIAISKRQIDEEGNVYFTYTTNELCRVLNCQKQKAIAIKKELESFGLLLQKQMG
                     FNKQLGKNNPNRLYLAELKVSENDIYLLEKFDRENRENVDKSEGMKIIPTLDEKSDAE
                     SLGAQEGMKIIPCQNVDKSEGMKIIPELNNNILDTNRHNIDTEKDRLQDQLLLDNFET
                     IMTNDSIATFVPERVLNLIKTFSSSYSEAQKTVQTIHNAKKKAEIESGISIVFEELDS
                     YYVNAEQELYTTLLKAYQKLKTEKVENIQNLIFVYVKNWFIEKPIAAKVSSEKRLNYE
                     SSPSTITKDWLE"
     gene            3956..4288
                     /locus_tag="LLC22_002709"
     CDS             3956..4288
                     /locus_tag="LLC22_002709"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323647.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein TraE"
                     /protein_id="HBK5435914.1"
                     /translation="MSYTGILSLKDICHYGKRCTATEKITKKLSTGQSKTVVQCKKYI
                     IQKDKVSEEMIYYIGKQKQIILKDPIPLKELYPTIKHVYDQNGVLIGRRKNGVLRCTA
                     KGMGRLIG"
     gene            4907..5248
                     /locus_tag="LLC22_002710"
     CDS             4907..5248
                     /locus_tag="LLC22_002710"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF5406 domain-containing protein"
                     /protein_id="HBK5435915.1"
                     /translation="MKNYDPNIRLGTHTIKVSFQRWDYKGFVTFRRGGNCKGLDVLAL
                     DEDDLYDQTLTDNPIGFGLLPEDDEGNEWFKMTLMNDNGDELSVEDTWSYLSDYIVSF
                     EIIEFVADKEE"
BASE COUNT         1942 a          727 c          900 g         1770 t
ORIGIN      
        1 taggtatttt tattatatat agatttaaca tatgtcggtc ggttgattga tatagctaaa
       61 gttataactc aactgaagcc gattcatcta cacgaataaa gttgcgagtg ttctcggcta
      121 attcataaaa attgttatgt gttccatata gcaatactgg aataacttta ttttcttgaa
      181 tctcataagc aactctatac acggtgaccg catacttaaa tccattagac caattacctg
      241 ataaacctcc agttttttgc tcttacttaa atggatcaat ggcaatttca tcacaaacct
      301 atagaggatg agtgacttct gcctaattac gttaaaaaat attgaaagta actctatgta
      361 gcaaaaaata tctagaattt catttcctca aaactgatcg atattgtatc taaaaatata
      421 tactacctaa aataggtagt atatattaaa atatgtgctt ttgttagaaa aatcaataca
      481 taaattatca tatctgtata tgtcatttag gtatttcagt tatgttataa tagttttgct
      541 gtctgctacc ccggcctaat ctggcaaggg gaggaggaga tataatgaaa tacctttttg
      601 attttgtttt tgcaatcaag ccacttgcag atgtagtgtg cagttacctc tgcaaatggc
      661 ttgattgcaa aattgccaaa aaagacagta agcctacccg ttaattctat aatatagaaa
      721 cgtaaaaaaa accccatcag cctgcacgct gatggggttt ggtgatataa tgaaatacct
      781 ctttgttact cataattgta ccataattag tcacgaatgc aaccaataga aaaaactact
      841 tagaacggta gatcatcgct aataacaatg cattgtccac caaatggatt ttgtgaagca
      901 ttaaatacat tgttattaat tgtcgctgct tttaactagg cctctcccct tctattataa
      961 aagaagatat atatcatttc ttaattacct actaccttaa accaaaattt aagtactacc
     1021 taatttaagt attacttaaa caatctaaaa aatagttatc ccaattgtta tgcttttata
     1081 atacgattat ttgtaacaaa atgaatatta tataattaaa cactaccata tttaggtagt
     1141 gtttaattat tagcaaaaca aaaaatattt attctattct cttaacttca actaagttat
     1201 gctgcacacc tttatataaa tcatatgcaa ctcattagct agacaaacta caagcatgta
     1261 gttttatctg ttaattatgt actacctaaa taaagtagtt tataattagc aagtatatat
     1321 atttaaaaat ttaagattaa tttttttatg acttgtacaa atttatctga tattctctta
     1381 ttaagaacta cctaatttgg gtagttctta ttttttacat tttaagtagt atttaattgc
     1441 aatttggtag tattttttta ttatcttatt cttagaacgg tagtacttaa tataaatata
     1501 ggtagtatct aatttaagta ttaatggtag tatctaaatt aacaggtagt atgtaactac
     1561 tttaaagtaa tttttttcag attaacacag tagtatctta ttaaataagt taattttaat
     1621 ggtagtacat aattattata tatatctgac attggtagta cttattgtat tttttagtag
     1681 tatataatct attgttttct agcctaaagc cttgtcttat aagaataata taatatatac
     1741 tactgaaata aggtagtata tattactagt aatggtagta tgttttatat gcataaggta
     1801 gttcttaatt tattttttgt tttgacactg gtagtactta attatcttta attttaaaac
     1861 taaattttat tcatacgttt ttctggtagt atttaattat aaataatatt tatttaaagt
     1921 agttcttaat gactttaaag gtagtacata attcatttta tttctgattt taggtagtat
     1981 ttaattaaaa aacagtttta atgcgtttgc attttttatt tatctttgct attttcgaaa
     2041 agagtaggta attttacata aataaaacaa cgtgaaagta gaggatctac aatgactgat
     2101 tttaaatttt ttaaggcgga tagagtttac aacgaattat tttatcaatt tccaaaagtc
     2161 tttattgttt ctgacgaata caaaaaaatg aaagattcaa ctaagattgc ctatatgctt
     2221 ttaaaagcaa gattagagat cgcaatcagc aaacggcaaa tcgatgaaga aggtaatgtt
     2281 tattttactt atacgacaaa tgaactatgt agagtattaa actgccaaaa acaaaaagcg
     2341 atagcaatca aaaaagagtt ggaatccttt ggtttattat tacaaaagca gatgggattt
     2401 aacaaacagt tagggaaaaa taatcctaat agactatatc tagcagaatt aaaagtctca
     2461 gaaaatgata tctacttact cgaaaaattt gatagagaga atagggaaaa cgttgataaa
     2521 tcagagggta tgaaaatcat acccaccctc gacgaaaaat cagacgctga atcccttggg
     2581 gctcaagagg gtatgaaaat cataccgtgc caaaacgttg ataaatcaga gggtatgaaa
     2641 atcataccag aacttaataa taatatatta gacactaata gacacaatat agacactgaa
     2701 aaagaccgcc tacaagatca attgttgtta gacaattttg agacaattat gacaaacgac
     2761 agcattgcta cgtttgtccc tgaacgagta ttaaatttga taaaaacatt ttcttcaagt
     2821 tacagtgaag ctcaaaaaac cgtccagact attcataatg caaagaaaaa agctgaaata
     2881 gaaagtggta tttcgatagt ttttgaagaa ctcgatagtt attatgtcaa tgcagaacaa
     2941 gaattataca cgacactgtt aaaagcctat caaaaattaa aaaccgaaaa agtcgaaaat
     3001 atccagaacc tgatttttgt ctatgtaaaa aattggttta tcgaaaaacc aatagctgct
     3061 aaagtatcaa gtgaaaaacg tttgaattat gaaagctccc caagcactat tacgaaagac
     3121 tggttagagt gaaactttac tgacaaagtg attgttgctt catggagtaa cattaaaatt
     3181 aaaaattttt tattattcta attatattac gaatattaca aaataatagc tattttaata
     3241 gaatttataa gttaaaatat tatgataaaa atcacaaacg tagcctttta cgtcataagt
     3301 gttaaaagaa ataattaatt tcaaatatag aaaagggaac gtatgtttgc atactccttt
     3361 tttttgagtt ataataatac gcgaagagag ataatttcat tatttaaaca agctaaaaat
     3421 cttgatatta cttcttttca ggcaatacga atattattcg cttacatttt ttgtataaat
     3481 ttaattgtct gctatgcttg tgatgaattg attttcgttc tgcacttttg gatgataaat
     3541 ttggacaatt gaaaatacaa aaaaaagaaa ggcggtatga actcggaagg ctggtaacct
     3601 tcgtcagcgt tcatacacgg cattaagatt tggcccttaa tgcgttaacc tttcagtgtt
     3661 acggtattac ccgcaatgga tttagtataa cagatattca aaagtgatac cacttttttt
     3721 ggctgtgtta aggttaaaaa tacgtgatat tacgatgaat ctatgcctaa gcacaatgtt
     3781 ataaaaatgt ccgtgtggct ctttgccgta tgacgaacgc tgaaattaga gggaacgcat
     3841 gtttggatgc gttccctctt ttttgtttgt catgaacgaa aatcaattct ctatttttga
     3901 aaaataacaa gaaaaacttg ttaaaaatat ttaaagaaat tgggtggttt attttatgtc
     3961 atatacagga attttgagtc tcaaagatat ttgtcactac ggtaaacggt gtaccgctac
     4021 agagaaaatc acgaagaaac tatcaactgg ccaaagtaaa accgttgtgc agtgtaagaa
     4081 atatataatc cagaaagaca aagtctcaga ggaaatgatt tattacattg ggaaacaaaa
     4141 gcaaataatt ttaaaagatc ctatcccctt aaaagagcta tatccaacaa tcaaacatgt
     4201 ttatgaccaa aacggtgtac tgattggtcg aagaaaaaat ggagtcttgc gttgtaccgc
     4261 aaaagggatg gggcgtttga tcggctgaat tgatcattct cataacttgt attttatcgt
     4321 ttttcgcttg cttgaaaata ttgtcgagac ttctaaagga acttagagtc actagaaaaa
     4381 taaggagtag acttgatcta tcaacaattc ccttcgggga gtgacggggt aggttttaac
     4441 gattggtaac gtaaaaaatt ggtcaatcga gtaaatgcgc ttgtttggat agtggtgaaa
     4501 tgaatttgtg taaataataa gcgcagagta aacaagaggg aatttagaag ttagacaagt
     4561 tagaatagcg tctagattaa tcatgagcag ctactaaggg atctagactt tgacgcaaac
     4621 tcatggaata aggagtaggt cttctcgtaa tggggaggac gcacaagaaa ttgtgtcgtg
     4681 tgctgcagta catgtagata cttgcgagga cgttgattat tggatcaatc gagcatttac
     4741 cgctgtctac tagggtttct cgtttcggac gccataaacg agtcgaaatt ttttatgtat
     4801 ttttaagtaa acgaaaaacg ataaaatatg aacaagtcct gaataaagtg aaaaaattga
     4861 tataaaacat agagaaaatg aaatttacgt aatggaggaa tgacaaatga aaaattatga
     4921 tccgaatata cgattgggca cacatactat taaggtttct ttccaacgtt gggattacaa
     4981 aggatttgtg acgtttagaa gaggcggaaa ttgtaaagga ttagatgttt tagcattaga
     5041 cgaggatgat ttatacgatc aaacattgac tgataatcca attggattcg gcttgctacc
     5101 tgaagatgat gaaggtaatg aatggtttaa aatgacgctt atgaatgata atggagacga
     5161 attatctgtt gaagatactt ggtcatattt gagtgattat attgtcagct ttgaaatcat
     5221 tgaatttgta gcggataaag aagaataaaa actggaggaa taaattttac agataaaggc
     5281 ttagaaggag tcacgatgat taataaaaag gtagtattac cttaggcatt gagtaagga
//
LOCUS       DAFBVQ010000109         5255 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.114, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000109 DAFBVQ010000000
VERSION     DAFBVQ010000109.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5255)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5255)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5255
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.114"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(46..366)
                     /locus_tag="LLC22_002711"
     CDS             complement(46..366)
                     /locus_tag="LLC22_002711"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326480.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1827 family protein"
                     /protein_id="HBK5435916.1"
                     /translation="MKLVNVTNSHSRLVLNQLENTDAHLVKVYTAGNTTIVYTEAPEH
                     NEILLINDKRKIQPKEIEDAKNYFLDKIKDAVYHEDEIKVIELAGLVEISIPKHELGA
                     TLAV"
     gene            complement(514..2748)
                     /locus_tag="LLC22_002712"
     CDS             complement(514..2748)
                     /locus_tag="LLC22_002712"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287598.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5435917.1"
                     /translation="MLCQNCGKNEATIHLYATVNGQRTQLDYCQSCYQKIKNQQNGGL
                     TNMAQNDPFGFGSLDDLFRSMSRQMQQQGNYEQTPPTQFGGNNNFNGGQPPQGNTEGL
                     LGEYGINITEQARQGDIDPVIGRDDEIKRVIEILNRRTKNNPVLIGEPGVGKTAVVEG
                     LAQKIVDGDVPQKLMDKEVIRLDVVSLVQGTGIRGQFEERMQKLIEEIRQAENVILFI
                     DEVHEIVGAGSAGDGNMDAGNILKPALARGELQMVGATTLNEYRIIEKDAALERRMQP
                     VRVDEPTVEETISILKGLQKRYEDYHHVKYTDEAIEAAATLSNRYVQDRFLPDKAIDL
                     LDETGSKKNLTIQIVDPKTIEKKLQKAEEQKVLASREEDFEKAAYYRDQINKLQKMKE
                     RQLTEEETPVITEKDMEKIVEQRTGIPVGELKEKEQTQLKNLADDLKAHVIGQDNAVD
                     RVAKAIRRNRVGLNKQNRPIGSFLFVGPTGVGKTELAKQLAYELFGSQDSMIRFDMSE
                     YMEKHSVSKLIGSPPGYVGYEEAGQLTEKVRRNPYSLVLLDEVEKAHPDVLHMFLQIL
                     DDGRLTDAQGRTVSFKDTIIIMTSNAGTGKVEANVGFGAAREGVTRSVLNQLNNYFTP
                     EFLNRFDGIIEFSALSKENLMTIVTLMLDDVNQMLAAQQLHIEVPTNVKEKLVDLGYD
                     PSMGARPLRRTIQEQIEDGIAEFYLDHPSIHELKAKLDKDGKIIVTSKPERLAKESAE
                     ETAE"
     gene            3227..3493
                     /locus_tag="LLC22_002713"
     CDS             3227..3493
                     /locus_tag="LLC22_002713"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010773230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphocarrier protein HPr"
                     /protein_id="HBK5435918.1"
                     /translation="MEKKEFHVVAETGIHARPATLLVQTASKFNSDVNLEYKGKSVNL
                     KSIMGVMSLGVGQGSDVTITAEGADEADAMAAIVETMKKEGLSE"
     gene            3493..5220
                     /gene="ptsP"
                     /locus_tag="LLC22_002714"
     CDS             3493..5220
                     /gene="ptsP"
                     /locus_tag="LLC22_002714"
                     /EC_number="2.7.3.9"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876303.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoenolpyruvate--protein phosphotransferase"
                     /protein_id="HBK5435919.1"
                     /translation="MVEMLKGIAASDGVAVAKAYLLVQPDLTFSKATVEDTAAEEARL
                     DAALAKSTEELQQIREKAAQSLGEAEAQVFDAHLMVLSDPEMVGQIKQNIKDNSVNAE
                     SALKEVTDMYIGMFEAMEDNAYMQERAADIRDVAKRILAHLLGVTLPNPSMINEEVVV
                     VAHDLTPSDTAQLDRNFVKAFVTDIGGRTSHSAIMARSLEIPAIVGTKEITAKVKEGD
                     ILAVNGIEGDVIIDPTDEQKAEFEKAGADYAAQKAEWEKLKNAETVTADGKHFELAAN
                     IGTPKDLVGVHNNGGEAVGLYRTEFLYMDSPDFPTEDDQYEAYKAVLEGMEGKPVVVR
                     TMDIGGDKELPYLQLPHEMNPFLGYRALRISLSEQGDEMFRTQMRALLRASVHGNLRI
                     MFPMVATLKEFRAAKAIFEEEKQKLISEGKEVSDTIQVGIMIEIPAAAVLADKFAKEV
                     DFFSVGTNDLIQYTMAADRMNERVSYLYQPYNPSILRLIKNVIDAAHAEGKWAGMCGE
                     MAGDQTAVPLLVGMGLDEFSMSATSILKTRSLMKRLDTAKMAELADRALKECDTMEEV
                     VELVHEYVK"
BASE COUNT         1580 a          983 c         1057 g         1635 t
ORIGIN      
        1 tttacttttg tcccacgctc tttaattatt atgttcaaaa tttgtttaca cggctaatgt
       61 agcgcctaat tcatgttttg gaatcgagat ttcaacaagg cctgccaatt cgattacttt
      121 gatttcatcc tcgtggtaaa cggcgtcttt gattttatct aagaaataat ttttagcatc
      181 ttcgatttct ttcggctgga ttttacgttt gtcattgatc agcagaattt cattatgttc
      241 aggggcttca gtgtagacaa tagtggtatt tccggctgtg tagaccttga ctagatgggc
      301 atcagtgttt tcaagctggt ttaatacaag acgggaatgg ctgtttgtta catttaccaa
      361 tttcatggcg ctcacctctt ttatgtattt ttaattgctt gtttctctta ttataatttc
      421 ttttttataa aatgaacagt attttgactt ttctgaaaaa agaatgagac ggcatttctc
      481 aaagaaatac cgtctcacgc tataaaactg gatttattca gccgtttctt cggctgattc
      541 tttagccaaa cgttctggtt tagaagtaac gatgattttt ccatctttat ccagttttgc
      601 tttcaactca tggatagaag ggtgatcaag ataaaattca gcgataccat cttcgatttg
      661 ttcttggatc gtgcgtcgaa gaggacgagc acccatagat ggatcatagc ctaagtcaac
      721 taatttttct ttgacattcg taggaacttc gatgtgaagt tgctgtgctg ccagcatttg
      781 gttgacatcg tctagcatta gtgtgacgat tgtcatcaag ttttcttttg ataatgcact
      841 gaattcgatg atcccgtcaa aacggttcag aaattctggt gtaaagtagt tgtttaattg
      901 gttcaataca gaacgagtaa caccttcgcg tgccgcacca aaaccaacgt ttgcttctac
      961 tttaccagtt ccggcattac ttgtcataat gatgatcgta tctttaaagc tgaccgttct
     1021 tccttgtgca tctgtcaatc gaccatcatc taagatttgc aagaacatat gcaaaacatc
     1081 tggatgagct ttttctactt catctaacaa gacaagactg taaggatttc tccgtacttt
     1141 ttctgttaat tgaccagctt cttcgtatcc gacataacct ggaggagaac caatcaattt
     1201 agagacacta tgtttttcca tatattcaga catatcgaaa cgaatcattg aatcttgtga
     1261 accgaatagt tcgtaggcaa gttgtttcgc aagctctgtt ttacctacac cagttggtcc
     1321 aacaaataag aaggagccga ttggacgatt ctgtttgttt aatccaacac ggtttcggcg
     1381 aatcgctttc gctactcgat ctacagcgtt atcttgtccg atgacatgag ctttcaagtc
     1441 atctgctaag tttttcagtt gtgtctgttc tttttctttt aattcaccca ctggaatacc
     1501 tgtccgttgt tcaacgattt tttccatatc tttttcggta atcacaggtg tttcctcttc
     1561 agtgagctga cgttctttca ttttttgaag tttattgatc tgatcgcgat aataagctgc
     1621 tttttcgaaa tcttcttctc gagaagctaa aactttttgt tcttctgctt tttgcagttt
     1681 tttctcgatt gttttaggat caacgatttg gatcgtcaag tttttcttag aacctgtttc
     1741 atctagcaaa tcgatggctt tatccggcaa gaagcgatct tggacgtaac gattggataa
     1801 agttgcggct gcttcgatgg cctcatcagt atattttaca tgatgatagt cttcataacg
     1861 tttttgcaaa cctttcaaaa tactgatcgt ttcttcgaca gttggttcat ctacccgtac
     1921 aggttgcata cgacgttcta aagcagcgtc tttttcgatg atgcggtact catttaaggt
     1981 agtagcacca accatttgca attctcctcg agctaaagct ggttttaaaa tattaccagc
     2041 atccatattt ccatcaccag cagaaccagc accgactatt tcgtgaactt catctatgaa
     2101 taggatcaca ttttctgctt gacggatctc ttcaatcaat ttttgcatac gttcttcaaa
     2161 ttgtcctcgt ataccagtac cttggactaa agatacgaca tctaaacgaa tgacttcttt
     2221 gtccattaat ttttgcggta catcaccatc tacgattttt tgtgctaaac cttcaacaac
     2281 tgctgtttta ccaacacctg gttctccaat caagacagga ttgttcttgg ttcggcgatt
     2341 taaaatttca atgactcgtt tgatttcgtc atcgcgtccg atcacaggat cgatatcacc
     2401 ttgtcgtgct tgttctgtga tattgattcc gtattctccc aataaacctt ctgtattgcc
     2461 ttgaggtggc tgaccaccat tgaagttgtt gtttccgcca aattgtgttg gtggtgtttg
     2521 ctcataattt ccttgctgtt gcatttggcg agacatggaa cggaaaagat cgtccaaact
     2581 gccaaatcca aatggatcat tttgggccat attagtcaga cctccatttt gttgattttt
     2641 gattttttga taacagctct gacagtaatc gagttgtgtc cgctgaccat tgacagtggc
     2701 atacaagtga atcgttgcct cattcttgcc gcagttttga caaagcatga atcattcacg
     2761 tcctttcaca aaaatgggta catccatatt ttacatctcg tttttcatga ggtaaaagaa
     2821 taacccctag ttttttaaga gatttatgag gtagaaaagg tgaaatctct attgaccatt
     2881 cctgaccttt gactcttatt atactaaaaa taaaaaggga agcaagtaat tcgtttcata
     2941 tgaaaacaaa gagggtcaaa ggaaagaatg ataaacgtca ggagaagaga aagcgacaag
     3001 aaaaaggaaa taaacacgtt tgttataaaa tgtgaagaaa aggatgaaaa agaatccgga
     3061 ataatttgaa tacttttatc tgaaattgaa tgaaaactgt tgtatctaac gaaaaaaaat
     3121 gttaatcttt acagatgaaa gggtggcatt tgttaggatt ctctgaatta ctaaaaaaga
     3181 aaaccctcac ataaaaacaa cactcactta aaggagaccg attaatatgg aaaagaaaga
     3241 atttcacgta gtagcagaaa ctgggatcca cgctcgtcca gctacactat tagtacaaac
     3301 agcaagcaaa tttaactctg atgtaaactt agagtataaa ggtaaatcag taaacttgaa
     3361 atcaatcatg ggcgttatgt ctttaggtgt aggtcaaggt tctgatgtta ctattactgc
     3421 agaaggtgct gacgaagctg atgcaatggc agcaatcgtt gaaacaatga agaaagaagg
     3481 cttatctgaa taatggttga aatgctaaaa gggattgccg ctagtgacgg tgtagccgtt
     3541 gcaaaagctt acctgctagt tcaaccggat ttaacattca gtaaggcaac agtagaagat
     3601 actgcggctg aagaagctcg tttggatgct gcattagcta aatctactga agaattgcag
     3661 caaattcgtg aaaaagcagc gcaaagctta ggtgaagcag aagcgcaagt atttgatgcc
     3721 catttgatgg ttctttcaga tccagaaatg gtaggtcaaa tcaagcaaaa tattaaagac
     3781 aacagcgtaa atgctgaatc agcgctaaaa gaagtaacgg atatgtatat cggtatgttc
     3841 gaagcaatgg aagataatgc ttatatgcaa gagcgtgctg cagatattcg tgacgttgct
     3901 aaacgtattt tagcgcactt attaggcgtt actttaccaa atccatcaat gatcaacgaa
     3961 gaagtggtcg ttgttgcaca tgacttgact ccaagtgata cagcacaatt agatcgcaat
     4021 tttgtaaaag cgtttgtaac agacattggt ggacgtactt cacattctgc tatcatggca
     4081 cgttctttag aaattccagc aatcgttggg acaaaagaaa ttactgctaa agtcaaagaa
     4141 ggcgatattt tggctgtcaa cgggatcgaa ggcgatgtaa tcatcgatcc tacagatgaa
     4201 caaaaagctg aatttgaaaa agcaggtgca gattacgcag cacaaaaagc agaatgggaa
     4261 aaattaaaaa atgcagaaac tgtcacagct gacggcaagc attttgaatt agctgcaaac
     4321 atcggaacac caaaagatct agttggtgtc cataataatg gtggagaagc agttggtctg
     4381 taccgtactg aattcctgta tatggattct ccagacttcc caacagaaga tgaccaatat
     4441 gaagcttaca aagctgtatt agaaggtatg gaaggaaaac ctgtagttgt tcgtacaatg
     4501 gacatcggtg gagataaaga actaccatat ctgcaattac ctcatgaaat gaatccattc
     4561 ttaggatatc gtgcattgcg tatcagttta tctgaacaag gcgacgaaat gttccgtaca
     4621 caaatgcgtg cattgcttcg tgcatctgtt catggtaatt tacgtatcat gttccctatg
     4681 gtagctacac tcaaagaatt ccgcgcagca aaagcgatct ttgaagaaga aaaacaaaaa
     4741 ttgataagtg aaggcaagga agtatctgat acgatccaag tcggcatcat gatcgagatt
     4801 ccagcagcag cagtcttagc agacaagttt gcaaaagaag tagatttctt ctctgtaggt
     4861 acgaacgatt tgattcaata cacaatggca gcagaccgta tgaacgaacg cgtttcttac
     4921 ttgtaccaac catataaccc atcaatttta cgtttgatca aaaatgtaat tgatgcagca
     4981 cacgctgaag gaaaatgggc aggtatgtgt ggagaaatgg ctggagatca aacagctgtt
     5041 ccattgctag taggtatggg tctagatgag ttctcaatga gtgcgacatc tattcttaaa
     5101 acgcgtagtt taatgaaacg cttggacaca gcgaaaatgg ctgaacttgc tgatcgtgca
     5161 ttgaaagaat gcgatacgat ggaagaagtc gttgaacttg ttcatgaata tgtaaaataa
     5221 acaacgtatc aaaagctggt gtggcttgta aaaga
//
LOCUS       DAFBVQ010000110         5032 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.115, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000110 DAFBVQ010000000
VERSION     DAFBVQ010000110.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 5032)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 5032)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..5032
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.115"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(178..681)
                     /locus_tag="LLC22_002715"
     CDS             complement(178..681)
                     /locus_tag="LLC22_002715"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002348853.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HD domain-containing protein"
                     /protein_id="HBK5435920.1"
                     /translation="MTEKWREDEEYMSYVQDLLETEAVKKLANYTQHVHSTRLEHSIS
                     VSYYSYLLAKKWGGNAKATARAGLLHDLFYYDWRTTKFDEGTHAYIHPRIAVKNAEKI
                     TDLSDLERDIILKHMWGATIAPPKYKEGYIVTFVDKYCAVKEAAQPMSASMRKRWQRY
                     FGKESSI"
     gene            complement(804..1568)
                     /locus_tag="LLC22_002716"
     CDS             complement(804..1568)
                     /locus_tag="LLC22_002716"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="RNA methyltransferase"
                     /protein_id="HBK5435921.1"
                     /translation="MKEIQSAKNPRIKELKKLHKKKYREEKAEYLLEGFHLIEEAASS
                     DAEIKELFVTQRGMKEWGDWLAVNKEISTFLVSDEVMTAMSDLPTPQGILAVMTLTSE
                     DTPDFSGGWLLLDNVQDPGNVGTMIRTADAFGMAGVLLGKGTADIYSTKVLRSMQGSN
                     YHLPVLQKDLADVIPVMKGKGFTVYGTELNEEAHALDKVEKTEDFAIIMGNEGQGVSQ
                     EILSLTDQNVYIPMKGNAESLNVGVAAGIVLYHFSL"
     gene            1676..1951
                     /locus_tag="LLC22_002717"
     CDS             1676..1951
                     /locus_tag="LLC22_002717"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acylphosphatase"
                     /protein_id="HBK5435922.1"
                     /translation="MRKVKMNVQGRVQGVGFRYMTKMVADQLGVTGTVKNEDDGSVTI
                     EAIGNDDIIQKFIEEVKKSPSPSGRVQYVDVQEDPMIEERKKFDVVG"
     gene            complement(2152..2499)
                     /locus_tag="LLC22_002718"
     CDS             complement(2152..2499)
                     /locus_tag="LLC22_002718"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435923.1"
                     /translation="MIPSVSFLFKKLKTFFILPEIEESNELTASDRSAFLLPVFNTWG
                     KAPQKQPYRRCSKVSFLVLRQIYAKMWKAIFTKFSLILKTKRLFHNQSLMLDADQLFH
                     NLIDGVLSAASRY"
     gene            2667..3596
                     /gene="yidC"
                     /locus_tag="LLC22_002719"
     CDS             2667..3596
                     /gene="yidC"
                     /locus_tag="LLC22_002719"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="membrane protein insertase YidC"
                     /protein_id="HBK5435924.1"
                     /translation="MNKWKNWLLGSGLVSILLFLSGCVRMDSNGNPDTSGIVYRVLVH
                     PMGQAITYLVENFNWSYGWAVIAMTVIVRIIILPLGISQSKKTMIQSEKMQALKPQVE
                     AAQQKLKAATTREEQMAAQAEMQQVYRENGLSMTGGIGCLPLLIQMPIFSALYFTARY
                     TEGIRESSFYGIDLGSPSMVLVAIAGVAYLLQGYISTIGIPEEQKKTMRTMLIVSPAM
                     IVFMSISAPAGVTLYWVVGGVFSCLQTFITNVMMKPRLKAQVAEELKQNPPKQVVTPR
                     KDVTESAKPADNKQPKNSTNNKGRNAGKQQKRK"
     gene            3699..5032
                     /locus_tag="LLC22_002720"
                     /pseudo
     CDS             3699..5032
                     /locus_tag="LLC22_002720"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012008915.1"
                     /note="frameshifted; internal stop; incomplete; missing
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182 family transposase"
BASE COUNT         1593 a          963 c          943 g         1533 t
ORIGIN      
        1 caaaagtcgt gtcaaagtcc cttgtttcga atgaatggtg ttcaaaagct tgcatctgca
       61 gtaataagcc gaaacttcac aaaaatttga gaagtaattt tcgtaaattc cttcttattt
      121 cttgaagctg accacttctg tcacaacctc aatatggtct attattggtt ttacctgtta
      181 aatcgaggat tctttcccaa agtaacgttg ccatctctta cgcatacttg cagacatggg
      241 ctgagccgct tctttgactg cgcagtattt gtccacgaat gtcacaatat atccttcttt
      301 atacttaggc ggtgcgatcg ttgcacccca catgtgcttc aaaatgatat ctcgctcaag
      361 atccgacaaa tcggtgattt tttctgcatt ctttacagca attcttggat ggatatacgc
      421 atgtgtcccc tcgtcaaatt tcgtcgtacg ccaatcatag tagaacagat catgcaaaag
      481 tccagcacgc gctgttgctt tagcattgcc accccatttt tttgcgagca gataactata
      541 gtaagaaaca ctgatggaat gctccaaacg agtggaatga acatgctgtg tgtaattcgc
      601 taattttttc actgcttctg tttctaaaag atcttgtaca taagacatat attcttcgtc
      661 ttcacgccat ttttctgtca taattatcga tctgccacct ttttgaattt cattttcttc
      721 tgaaattgat ctaagtatac caccagtgtt cggattattc tagtcgctct agataaaata
      781 gctaaagctt aatagttcct taatcataaa gaaaaatgat aaagaacgat ccctgctgcg
      841 actccgacat tcaatgattc cgcatttcct ttcattggga tatatacgtt ctgatcagtc
      901 aaagacaaga tttcctgact gactccctga ccttcgtttc ccatgattat agcgaaatcc
      961 tctgtttttt ctactttgtc taatgcatgt gcttcttcat ttaattctgt accgtacacc
     1021 gtaaaccctt tgcctttcat tacagggatt acatctgcca aatctttttg taacacaggc
     1081 aaatgataat tgcttccctg catgcttcgc agcacctttg tactataaat atctgccgtt
     1141 cctttaccta ataaaacacc agccatacca aacgcatctg ccgtacggat catcgttccc
     1201 acatttccag gatcctgtac attatctagt aaaagccagc ctcctgaaaa atctggcgta
     1261 tcttcagatg ttaacgtcat cactgctaag atcccttgcg gtgtaggtag atctgacata
     1321 gcggtcatga cctcatctga aactagaaaa gtagaaatct ctttgtttac agccagccag
     1381 tctccccatt ctttcatacc tctctgtgtc acaaaaagtt cttttatttc tgcatcagac
     1441 gacgcagctt cttcgatcag atggaaccct tccaaaagat attctgcctt ttcttctctg
     1501 tatttctttt tatgtagttt ttttaattct ttgattcttg gattttttgc tgattggatc
     1561 tctttcacat tccttcacct cacctgatta tatcatggaa taggtgcttg agcttgtttc
     1621 atcctaaaaa aatcggtatc attgatttat aaaacaggaa agaaaggtga cgaacatgcg
     1681 caaagttaaa atgaatgtcc aaggacgtgt ccagggcgtg ggatttcgct atatgaccaa
     1741 gatggttgct gatcagttag gcgtgaccgg aacggtaaaa aacgaagacg acggctcagt
     1801 cacaatcgaa gcaatcggaa atgacgacat catccaaaaa tttatcgaag aagtcaagaa
     1861 gtctccgagc ccaagtggac gagtgcagta tgtggatgtc caagaagatc cgatgattga
     1921 ggaacgaaag aaatttgatg tggtgggata aggttgtgaa aaggtcgctt agttttgagt
     1981 attaaggaaa attttgtgaa aatggctttc cacatttttg cataaatttg acttaatacc
     2041 gagaaactga cttttgaaca ccgtcgataa ggttgttttt gaagcgcttt gcctcgagta
     2101 ttaaggagaa acattttcaa aatagcttct catattttga aatgtaatga cttaataccg
     2161 agaggcagct gataaaacac cgtcaataag gttgtgaaaa agctggtctg catcaagcat
     2221 taaggactgg ttgtgaaaaa gtcgcttagt tttgagtatt aaggaaaatt ttgtgaaaat
     2281 ggctttccac atttttgcat aaatttgtct taataccaag aaactgactt ttgaacaccg
     2341 tcgataaggt tgtttttgag gcgctttgcc ccaagtatta aagacaggta gtaaaaaagc
     2401 tgatctatca cttgcagtga gttcatttga ctcctctatt tcgggcagaa taaaaaaagt
     2461 ttttagtttt ttaaataaga aagaaacact tggaatcact cttttctttc caagtatttc
     2521 tttcttgatt ttttgtcttt tttcaaaatt tttcgctacg aaaaagaaag aatatttata
     2581 tgaaatttct atgaagttga ttgaattcca tgcgcttttt tagtatagtt aagtttgtgt
     2641 aaaaattata gaagaggaag tattctatga ataaatggaa aaactggtta ttgggatccg
     2701 gacttgtcag tatcctgctc tttttatctg gctgtgtgcg gatggattca aacggaaacc
     2761 ctgacacttc aggaatcgtt tatcgagtac tcgtccatcc tatgggccaa gcgattacat
     2821 atctagttga gaatttcaat tggtcttacg gctgggcagt tattgcaatg actgtgatcg
     2881 tccgtatcat catcttgcca ctaggtatca gtcaatcaaa aaaaacaatg atccaatctg
     2941 aaaaaatgca agcgttaaaa ccacaagttg aagcagcaca acaaaaacta aaagctgcaa
     3001 caacacgtga agaacaaatg gcagcacaag cagaaatgca acaagtatat cgcgaaaacg
     3061 gattgagtat gaccggcgga atcggctgtc tgcctctatt gatccaaatg ccgatcttct
     3121 ctgccttgta ttttacggct cgctacacag aaggtatccg tgaatcatct ttttacggca
     3181 tcgatctagg ctcaccaagt atggtgcttg ttgccattgc aggggtcgct tatctgcttc
     3241 aaggatatat ttcaacaatc ggtattcctg aagaacagaa aaagacgatg cgtacgatgc
     3301 tgatcgtctc tcctgctatg atcgttttca tgtcgatcag tgcgccagcc ggtgttacac
     3361 tttactgggt agtgggtggt gtgttcagtt gtctgcaaac attcatcaca aacgttatga
     3421 tgaaaccacg tttgaaagca caagtggcag aagagttgaa acaaaatccg ccaaaacaag
     3481 tcgtcactcc aagaaaagac gtgacagaat cggcaaagcc agctgacaat aaacaaccaa
     3541 aaaacagtac aaacaacaaa ggccgcaacg caggaaagca gcaaaagcgg aaataaaaat
     3601 atatgacaaa aaactgtaga caaataaaaa aatttctttg ttctacagtt tttttgttac
     3661 aatcaaagaa aacgtcgctt ttcgaggagg aatgtataat gatgtccaaa taatcaatgg
     3721 atagtcgaat ggaagaagcc aaaatttcgc tagatgcact tgttcctaaa aatcatttgg
     3781 tccataaaat tgacaaaata ttgttatttg attttattta tccaattgtt gaatcaactt
     3841 actcgaccat tggtcgtcct agcgttgatc ctgtcatctt agtaaaatta gtattcattc
     3901 aatatttatt taggattcgt tcgatgcgtc agtccattaa agaagctgaa acaaacctag
     3961 cttatcgttg gtttcttggg cttagtttaa tcgataaaat tcctcatttt tcaacgtttg
     4021 gtaaaaacta tgtacggcat ttcagagaaa ccgattgttt gaacagatat ttatcattat
     4081 ccttgaacaa gcagttgaag ctagatttat tcatgaagaa attttgtata tggattcaac
     4141 ctatattaaa gcgaatgcga aaaaacatat ttttacaaga gaaatggtac ataaataagc
     4201 cattttatac caaaaacaat tgaaagaaaa aattaatgaa gcaagaattg cagaaggcaa
     4261 acgtcctttt ggttcaatca ttcatcagga ggtggtagaa gggaaaatta gtgtcgcaga
     4321 tccagaaagt ggttattatg taaaaacaga acaagaaaaa cagtttgctt attctgctca
     4381 taccgtttgt gatgaaaatg gttttgtatt agatgtcatg attacgcctg gaaatctaca
     4441 tgacagccga atgctcgtgc cacaaatcga acgtgttaaa tcatgttgtg gtgtagctgc
     4501 tgatgctgcg tacaaaacac cttggaacgc caagtattta atcgatcgaa aactacgacc
     4561 catttttcct tatactcgac ccaaaagaag caaagaacgt tttaaaaaga aagattttta
     4621 ttatgatccc tattataact ggtacctatg cccaaatgat caaacacttc agtttcgcac
     4681 aactactcga gatggttata aaaaatatgt atctaaatct tttatttgtg aaagttgtct
     4741 attattgaaa aattatacag aaagccagaa acaccagaaa gaaatacatc gacatattta
     4801 ggaagactac ttagatgaag cagaacattt acgccatacg gtgtacaatc gcgaaaaata
     4861 taaaaaaaag aaaagaaacg attgaacgcg tttttacaga cgcaaaggaa aagcatggaa
     4921 tgcgctacac caaatatcga ggcttggaaa aaaccaggtg catacgatgc ttgtttttgc
     4981 cgcaatgaat ctgcaaaaat tagccatttg gcagtggggg catatgtctt ta
//
LOCUS       DAFBVQ010000111         4888 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.116, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000111 DAFBVQ010000000
VERSION     DAFBVQ010000111.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4888)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4888)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4888
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.116"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..467)
                     /locus_tag="LLC22_002721"
     CDS             complement(<1..467)
                     /locus_tag="LLC22_002721"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371668.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar transferase"
                     /protein_id="HBK5435925.1"
                     /translation="MESEDLLSRISEVHPNQVWLDKEKVEKRYIYLFFKRMIDIVGSI
                     IGLILASPLMFYVAYRIRKEEPGSPIFFCHTRVGKNGKTFKMYKFRSMCLDAEEKLEE
                     LLDQNEIEGAMFKMKEDPRVTKIGKIIRAKSIDELPQLWNVLKGDMSLIGPRPP"
     gene            complement(512..1276)
                     /locus_tag="LLC22_002722"
     CDS             complement(512..1276)
                     /locus_tag="LLC22_002722"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738108.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein phosphatase"
                     /protein_id="HBK5435926.1"
                     /translation="MIDLHCHILPGIDDGAENLEASIAMAEKAIQQGITHILCTPHHN
                     NGKYSNEKSQVISLVASLQAELEKRQLPLTLLEGQEVRITGTLIEDIHRDEILFTDLD
                     DTYLLIEFPTLEVPLYAEWLFFELLELGKTPVIVHPERNAHFREDPNHLLPFLDMGCL
                     AQITAPSYVGVFGKDIQKTAKTMVKHNLVQMAASDAHGVSKRTFYLKECYEQIAKDFG
                     KEKVVQMKQVAKDLINGDEISYPVYEEVKKKKFGLF"
     gene            complement(1304..2002)
                     /locus_tag="LLC22_002723"
     CDS             complement(1304..2002)
                     /locus_tag="LLC22_002723"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346049.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CpsD/CapB family tyrosine-protein kinase"
                     /protein_id="HBK5435927.1"
                     /translation="MARTQKQKAAQTHAVSLITLTNPSSPIAEQYRTIRTNIQFASAA
                     GQQIKTIVVTSSGPGEGKSTTAANIAVVFAKSGQRVLLVDADLRKPVVYKTFQLNNAR
                     GLSTALSSSGSVADVIQRTPVENLSILPSGPKPPNPSELLSSPRMDQILDEARQLFDV
                     VIFDMPPVVAVTDAQIMSSKTDGTLLVVRENTSRKESLNKAKELLEMVQARVLGVVYN
                     GAEHSKDAGYYYGN"
     gene            complement(2014..2793)
                     /locus_tag="LLC22_002724"
     CDS             complement(2014..2793)
                     /locus_tag="LLC22_002724"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326287.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine protein kinase"
                     /protein_id="HBK5435928.1"
                     /translation="MEETINLEEIFETLRKHLVTIIISMFAGLAISGIVTFFILTPKY
                     SSQAQLIVTLPQSDTANVNDVNTNLQMINTYKDMIVSDLVLNEVKDRLETEDNVKMTA
                     GQIKDAISVNQSQNSQMFSIQAISTNAVTAQQIANTTSQVFQENAKDVMNVDKISIIS
                     GAVANTTPVSPNNKLNLVIGLVLGMMVGVGLAFLFELLDRTVKDEKYVTDALGFPILG
                     TVPEMSAKELNAGIRKKGTAPARPKATNDKTAPSRRSRSRV"
     gene            complement(2809..3753)
                     /locus_tag="LLC22_002725"
     CDS             complement(2809..3753)
                     /locus_tag="LLC22_002725"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291712.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LCP family protein"
                     /protein_id="HBK5435929.1"
                     /translation="MARRRRKSRGKKIFLIILAVLIVLVLAIVGVGAKLYLDLSHSIE
                     KTYESVERTQGERTKPVDLDKQESFSVLLMGIDTGDLGRVDQGRSDTMMVAIVSPEDK
                     QTTIVSIPRDTYVDIVGRDTKDKINHAYAFGGAAMAMDTVQKYVDIPIDHYVSINMKG
                     LKELVDAVGGIEVNNDLTFSQDGYDFTIGKITLNGDQALSYSRMRYEDPNGDYGRQER
                     QRKIVEGVAKKVLSLNGVSNYQSVLNALESNMKTDMSFDEMKKIALDYREAFGTIKQD
                     QLQGEGFMQDNISYQKVSDQELDRVKKELKDQMNLENK"
     gene            complement(3799..4578)
                     /locus_tag="LLC22_002726"
     CDS             complement(3799..4578)
                     /locus_tag="LLC22_002726"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330065.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435930.1"
                     /translation="MEKPFVKSLTAVAVGAGAIAICLFGYHINNQRQHQQRINYAESA
                     ITNQKDTLTSLSKEVDKLYSTKEKIFLNPEITEETITSLSNKLSYVKLSADDYDIKES
                     ELPKEAVAIQDEKKAIVTQLDSAESKLKIQTAVNDLFTKNVSNWQQAVDDVIIKEKVT
                     SADVARVRENMSFFKDSPWKTVVMQYLGFADTQIAQVTQLDQLFDTMLKDGQVTATAT
                     YDQYLTALSQIEQIRNEKISAAYATKAQTVAQQMGYSNISY"
BASE COUNT         1290 a         1010 c          852 g         1736 t
ORIGIN      
        1 ggtggccgtg gaccaattag actcatatcg ccttttaaaa cattccatag ctgtggcaat
       61 tcatcaatgc ttttggcacg gataatttta cctattttag tgacacgggg atcttctttc
      121 atcttgaaca ttgcaccttc tatttcattt tgatcaagta attcttccaa tttttcttca
      181 gcatctaaac acatcgaacg gaatttatac attttgaatg tttttccatt tttaccaaca
      241 cgtgtatggc aaaaaaatat cggacttcct ggctcttctt ttctgattcg ataagctaca
      301 tagaacatca aaggagaagc taaaatcaaa ccaataatgc ttcctacaat atcaatcatt
      361 cttttaaaaa ataaatagat atatcgtttt tcaacttttt ctttatccaa ccaaacttga
      421 ttaggatgta cttcactaat acgagataat aaatcttcac tttccatact ttccctctct
      481 cctcatttcc tttttatcta cgaataaaga actaaaataa accaaacttc ttctttttta
      541 cctcttcata gactggataa ctgatttcat ccccgttgat cagatccttt gcgacttgtt
      601 tcatctgtac tactttttcc ttaccaaagt ccttagcaat ctgctcatag cactctttta
      661 agtaaaaggt acgcttagag accccatggg catcagaagc agccatctgc acgagattat
      721 gtttgaccat tgttttggct gttttctgaa tgtctttgcc aaatacacca acataacttg
      781 gcgcagtaat ttgggccaaa catcccatat ctaggaacgg aagcaaatga tttgggtctt
      841 ctcgaaaatg cgcgttgcgt tctggatgga cgatcactgg tgtctttcct agttctaaca
      901 actcaaaaaa aagccattct gcatataacg gcacttccag tgtcggaaat tcgatcagaa
      961 gatatgtatc atctaaatct gtaaataaaa tttcatctcg gtggatgtct tcgatgagcg
     1021 ttccggtaat acgtacttct tgtccttcca ataacgtcaa aggcaactgt cttttctcta
     1081 attcggcttg taacgaagcg actagagaaa tgacttgtga tttttcattg ctgtattttc
     1141 cattattgtg gtgtggtgtg cataaaatat gcgtgatgcc ttgctgaatc gctttttcag
     1201 ccattgcaat acttgcttct aagttttctg ccccgtcatc gattcctggt aggatatggc
     1261 aatgtagatc gatcatttct cttgtctcct ctcttcttat tccttaattt ccgtagtaat
     1321 aaccagcatc tttgctatgt tctgctccgt tgtatacaac acctaaaact cgtgcttgta
     1381 ccatctctag cagttctttt gctttattca atgattcttt acgtgatgta ttttcacgta
     1441 cgaccaataa agtgccatcc gtttttgaag acatgatctg tgcatctgtt acggctacta
     1501 ctggtggcat atcgaatatc accacgtcaa ataactgtct tgcttcgtct aggatctgat
     1561 ccattcttgg cgaacttaac aattctgatg ggttgggtgg cttaggtcca ctaggcaaaa
     1621 tcgacaagtt ctcgactggc gttcgttgga ttacatctgc tacacttcct gatgaactaa
     1681 gtgctgtact taatcccctg gcattgttca gctggaatgt cttatagacg acgggtttac
     1741 gtaaatctgc atcgactagt agaactcgtt gaccggattt agcaaaaacg actgcaatgt
     1801 ttgctgcagt ggtggatttt ccttctccag gacctgatga agtcacgaca atcgttttga
     1861 tttgctgacc agctgcggag gcaaactgga tattcgtccg gatcgtacga tattgttcgg
     1921 cgattggtga agatgggttt gttaatgtga tcaaactgac tgcatgagtt tgtgctgctt
     1981 tttgtttctg tgttcgtgcc atttttcttc ctcctagact cttgagcggc ttctgcgtga
     2041 tggggctgtt ttatcgtttg tagcttttgg tcgtgcagga gctgttcctt ttttacggat
     2101 accagcgttc aattctttcg ctgacatttc tggaactgtt cctaagattg ggaatcctaa
     2161 tgcatccgtc acatattttt catctttcac tgtccgatca agtaattcga ataagaatgc
     2221 cagacctacg cctaccatca ttcctaatac taagccaatc actagattca atttattatt
     2281 tggcgaaaca ggtgtcgtat tggcaactgc acctgaaata atcgagattt tatcgacatt
     2341 catcacgtct tttgcgttct cttggaaaac ttgtgaagtt gtgttagcga tctgttgagc
     2401 agtcactgca ttcgtgctta ttgcctggat cgagaacatt tgtgaatttt gtgactgatt
     2461 gacggagatc gcatctttga tttgtccagc agtcattttc acattgtctt ctgtttctaa
     2521 acgatctttg acttcattta gtactaaatc actgacgatc atatctttat acgtattgat
     2581 catttgcagg ttcgtattga catcattgac atttgctgtg tctgattgtg gcagtgtcac
     2641 gatcaattgt gcttgtgaac tgtattttgg tgtcaagatg aaaaatgtta cgattcctga
     2701 gatggccaag ccagcaaaca ttgagatgat gattgttacc aagtgtttgc gtaatgtttc
     2761 aaaaatttct tccaagttga ttgtctcttc cattttttct ccactttcct atttattctc
     2821 tagattcatt tgatctttta attctttttt tacacgatca agttcttgat cactgacttt
     2881 ttgataggag atattatctt gcataaagcc ttctccttgc agctgatctt gcttgatcgt
     2941 accaaatgcc tcccgataat ctaaagcgat ttttttcatt tcatcaaagc tcatgtctgt
     3001 tttcatattc gactctagag cattcaaaac ggattgatag ttgctgacac cgtttaaact
     3061 caatactttt tttgctacac cttctacgat ctttctttga cgctcttgtc taccatagtc
     3121 accatttgga tcttcataac gcatacgaga ataagataat gcctgatccc cgttcaatgt
     3181 gattttaccg attgtaaagt catagccatc ttgtgagaaa gtgaggtcat tattgacttc
     3241 gataccacca actgcatcaa caagttcctt tagccctttc atattgatag agacatagtg
     3301 atcgattggg atgtctacat atttttgtac ggtatccatc gccatggcag ctccgccgaa
     3361 tgcgtaagcg tggttgatct tgtcttttgt gtcacgacct acgatgtcga catacgtatc
     3421 acgaggaatg ctgacgatcg ttgtctgttt gtcttcagga ctgactatgg caaccatcat
     3481 cgtatctgat cttccttgat cgacccgacc taaatctcca gtatcaatcc ccatcaatag
     3541 aacagagaaa gattcttgtt tgtccagatc aactggtttc gttcgttctc cttgggttcg
     3601 ttccactgat tcgtaagttt tctcaataga atgtgagaga tccagatata attttgctcc
     3661 tactcctaca attgctaata ctaatacgat aagaactgct aaaataatca gaaatatttt
     3721 tttccctctt gattttcttc ttcgtcttgc catagtttcc tccgtttgct aaccttgctt
     3781 gaatcaacgt tttaactgtc aataacttat attgctatag cccatttgct gagcaacagt
     3841 ttgtgctttt gttgcgtatg ctgcgcttat tttttcattc cggatctgct ctatttgact
     3901 gagcgccgtc aaatattgat cgtaagtagc ggtggcagtc acttgaccat ccttcaacat
     3961 cgtatcgaat aactgatcta gttgcgtgac ttgcgcgatc tgagtatcag cgaatcctaa
     4021 atattgcata acaaccgttt tccaaggact atctttaaaa aagctcatat tttcacgtac
     4081 acgagcgaca tctgcacttg tcaccttttc tttgatgatg acatcgtcta cagcttgctg
     4141 ccagtttgat acatttttag taaacaaatc gttgacagct gtctggatct tcagttttga
     4201 ttctgcacta tctaactgtg tcacgattgc tttcttctca tcttggattg caacagcttc
     4261 tttaggcaat tctgattctt tgatgtcgta atcatctgct gaaagtttga cataggatag
     4321 cttatttgac aaacttgtga ttgtttcttc tgttatttca gggtttagaa aaattttttc
     4381 ttttgtacta tacagcttgt ctacttcttt tgataaagaa gtcaaggtgt ctttttgatt
     4441 ggtgatggca gattctgcat aattgatccg ttgctgatgt tgccgctgat tattgatatg
     4501 gtaaccaaac aaacagatcg caatagcacc tgcacctacc gccacagcag tcaatgactt
     4561 gacgaatggc ttttccatag attcactcct aagtattgat gatagataaa ttaagatata
     4621 attcacttac ataaaaatga cagcttttta ttttaaaaaa cataattaaa ctaatatatt
     4681 cacagaaata tttgtaaaca agttttccct atataatcat accacaaact gttttcttga
     4741 ctagggcaat ttatgattta aaagtaaata aaacattaat aagataacaa ttaatcgatt
     4801 tcatttttat ttccttaatt ttcataggtg tttttaaaag ttacacaaaa aataaaataa
     4861 caaaaaaatt aacattgaat taataata
//
LOCUS       DAFBVQ010000112         4790 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.117, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000112 DAFBVQ010000000
VERSION     DAFBVQ010000112.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4790)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4790)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4790
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.117"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(75..1073)
                     /locus_tag="LLC22_002727"
     CDS             complement(75..1073)
                     /locus_tag="LLC22_002727"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336119.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4767 domain-containing protein"
                     /protein_id="HBK5435931.1"
                     /translation="MKKWLLLLIGMGILFTGCTSENTRTKATIETDTTIETKKSKTQS
                     TEQTTTEMKQSVETSASSITESSSEEVKNTLWDTNKASKLETFVTQWGKTLGQEYKSY
                     NLQNNVSLYGTPLPQAVINGDWKMAINEAPVTVQWSEDGTGHADFNLVAVYSDVETGE
                     YLGQHVYFFGFQNGQPKVYLTQQNQGNENNYLYFNETQNQQLKQGFSDIVNGQTPQTP
                     VVEESTQQATTTTTQSTSSSGISSWEAAKESVLNNKALWLYDSPDKNVSNTNLISTNE
                     YMKDLMQDENGSYYSINIVTDDDGNTTMAGGKQFRVYTDGRISQRIGMTNNFQMIK"
     gene            complement(1148..1444)
                     /locus_tag="LLC22_002728"
     CDS             complement(1148..1444)
                     /locus_tag="LLC22_002728"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidase"
                     /protein_id="HBK5435932.1"
                     /translation="MAKLIVLGGLIYGGYWLYKYMLAHPNIDKGKVIKTVGVIIVGLI
                     ALTKKNNTNSPKIMRTYRCRGCGREISTSFNPSESPQGRDRCHTGYRHYWERID"
     gene            complement(1437..1730)
                     /locus_tag="LLC22_002729"
     CDS             complement(1437..1730)
                     /locus_tag="LLC22_002729"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002374115.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435933.1"
                     /translation="MEIDETCLSNSYKSMNDFFEEMELDSELLYQFYLAFRGQQISFP
                     MKMYDRELVRKRIENMIEQEKTVDIRQLTEVYGFSARWIQKVIKQKERRRVHG"
     gene            complement(1876..2427)
                     /locus_tag="LLC22_002730"
     CDS             complement(1876..2427)
                     /locus_tag="LLC22_002730"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005878891.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1643 domain-containing protein"
                     /protein_id="HBK5435934.1"
                     /translation="MIEKELVTTQTEVWRDPHHTHRYVFKRQWAIKGKEAEDKLAVVI
                     TIRPTDTEPFTNDLSMLLIEKNIRQLGFTGFIAVNLFSYTKAKSPRVFLRGNDEQSLE
                     ILTTVFTEKKINTIIFACGSITATSQVAYEQAKTIYDQLSAKQKKMTKVLINAEGKLS
                     HPLSIHVRNEWQLADSQLLFQEK"
     gene            complement(2601..2900)
                     /locus_tag="LLC22_002731"
     CDS             complement(2601..2900)
                     /locus_tag="LLC22_002731"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019722867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4'-phosphopantetheinyl transferase"
                     /protein_id="HBK5435935.1"
                     /translation="MLETAIEVLEKCAQLVTASEEWGYESVTMEKEEIEIGTLPKDVH
                     LPRLVMTHLYIYCAPEDGKDYVVYFITDITSQREFVRGLLVEGRLVWSQIGGTDE"
     gene            complement(2927..3235)
                     /locus_tag="LLC22_002732"
     CDS             complement(2927..3235)
                     /locus_tag="LLC22_002732"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332706.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF960 domain-containing protein"
                     /protein_id="HBK5435936.1"
                     /translation="MFQNKGQRYVTKGVMDSLPVELQALCWNLIDQNVQKQLPLDYLQ
                     IFEFSTEKGNQKLVHRQEEPEERKEYLISPKLRLKSVSQKIWAIDSGEYQTMLLPEEY
                     "
     gene            3540..4223
                     /locus_tag="LLC22_002733"
     CDS             3540..4223
                     /locus_tag="LLC22_002733"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335147.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435937.1"
                     /translation="MTTEHFDLANPVTKVDDIPDYEMYSQTIDSLNKRFGNRVLKGIE
                     IGYIASEKDRIIDYLADKDYDLKLLSVHHNGQFDYLDDEVKDMDPAIVIPQYFAQLSE
                     ALVVIEADVFAHFDYGFRVFGLSVAEFKQYEAQFLPILDQVIKNKLAFELNAKSAYLY
                     DNLALYEYVIDLYLSRGGTLFSVGSDGHYLEHFRFHFDDLFALLKANGVTELAIYQKG
                     KRIMVPLPV"
     gene            complement(4260..4757)
                     /locus_tag="LLC22_002734"
     CDS             complement(4260..4757)
                     /locus_tag="LLC22_002734"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5435938.1"
                     /translation="MNNQITLAYLDYDDLDALQVVSVVSFYESFIDGADPLDMQGYLQ
                     TQLTTEILAVELAQSTSKFIGIKDHQILIGYMKVNDEKDAIEIQRLYLLKDYQNKGLG
                     QRLLDEANRYAKTKQKRYLRLTVYEKNHAGIRFYERHGFKKIGIKHFPLGKQDRICPI
                     LEKEI"
BASE COUNT         1424 a          908 c          700 g         1758 t
ORIGIN      
        1 taaaaaaact gattctaaga aaattaaata atttttctca aaatcagttt ttctttgata
       61 aataatattt tcaattattt aatcatttga aaattgttag tcattccaat acgttgagaa
      121 attcttccat ctgtataaac acgaaattgt tttccaccag ccatggtcgt gtttccatca
      181 tcatccgtta caatattaat tgaatagtag cttccatttt catcttgcat tagatctttc
      241 atatattcat ttgtgctaat taaattagta tttgatacat ttttatcagg agaatcatac
      301 aaccataaag ctttattatt tagcacagat tctttagcag cttcccaact tgaaattcct
      361 gaactacttg tagattgtgt cgttgtagtt gttgcttgtt gagtagattc ttctactact
      421 ggtgtttgag gagtttgtcc attcacaata tcactgaaac cttgttttaa ctgttgattt
      481 tgagtttcgt taaagtacag ataattattt tcattacctt gattttgttg cgttaaataa
      541 actttaggtt gtccattttg aaaaccgaaa aagtaaacat gctgccctaa atattctcca
      601 gtttctacat cagaataaac tgctactaaa ttgaaatctg catgaccagt tccatcttct
      661 gaccattgta cggtaactgg tgcttcattg attgccattt tccaatcgcc attaatcacg
      721 gcttgtggta aaggagtgcc atacagactt acattattct gaagattgta gcttttatat
      781 tcttgaccta atgtctttcc ccattgtgtg acaaaagttt ctaatttgga agctttattc
      841 gtatcccaca aagtattctt aacctcttca gaagaagatt cagtgattga acttgcactt
      901 gtttccacag attgcttcat ttctgttgta gtttgttcag ttgattgcgt tttacttttt
      961 ttagtctcaa ttgttgtatc agtttctata gtcgctttag tcctcgtatt ctcagatgta
     1021 caaccagtga ataaaattcc cattcctatt agtaataaca gccatttttt cattatattt
     1081 ccccctttca atttctccct cacgtactta ttctatcaga caattaattg atctaaatgg
     1141 taatctttta atcgattctt tcccaataat gtcgatagcc cgtatggcag cggtctcttc
     1201 cttgaggact ctcagatgga ttaaaactag tagaaatttc ccttccacat cctctacagc
     1261 gataagttct cattattttt gggctattag tattattttt cttagttaga gctatgagtc
     1321 caactatgat taccccaact gtcttaatta cttttccttt atctatattc ggatgcgcaa
     1381 gcatatattt atataaccaa tatccaccgt aaattaaacc acctaataca atcagcttag
     1441 ccatgtactc gtctcctttc tttttgttta attacttttt gaatccatct tgcagagaaa
     1501 ccataaactt ctgtcaattg acggatatct acagtttttt cctgttctat catgttttcg
     1561 attctttttc taactaactc acgatcgtac attttcattg gaaaagaaat ctgttgccct
     1621 cgaaaagcaa gataaaattg atagagcaat tctgaatcca gttccatttc ctcaaaaaag
     1681 tcattcatac ttttataaga gttactcaaa caagtttcat caatctccat ctacacaccc
     1741 cctgttattt tttacataat gaaaatagca tattactggg tacattgata attcatataa
     1801 catgtatcat cacatgtatt tttaaagtca aaaagcatgt aaaactactt ataagtaaca
     1861 tgagaaaata aaatgttatt tttcttgaaa taataattga ctatctgcca attgccattc
     1921 attacgaaca tgaatactta gtgggtggga taacttacct tctgcattta tcaatacttt
     1981 ggtcatcttc ttttgtttcg cactcaattg atcgtaaata gtctttgctt gttcataagc
     2041 cacttgactc gtcgctgtaa tcgaaccaca agcaaaaata atggtattga ttttcttttc
     2101 tgtaaaaaca gtcgttaata tttccaaaga ttgttcatca tttcctcgaa gaaatacccg
     2161 aggacttttc gcttttgtgt acgaaaaaag attcacagca ataaaaccag taaatcctaa
     2221 ttgtcggata ttcttttcga ttaataacat actcaaatca ttcgtaaatg gttctgtatc
     2281 tgttggacga atagtaatga ctactgctaa tttatcttcc gcttcttttc ctttgatcgc
     2341 ccattgtcgt ttgaaaacat agcgatgggt atgatgagga tctcgccaaa cttctgtttg
     2401 tgtggtcact aattcttttt caatcatctc tttttctcct atgctatttt ttgttcaagc
     2461 acttcaatta ccattgccgt tataagtgtc aatactagtt gaaaatattt catattcttt
     2521 ctcctttttt cttcagaatt tgatgaatcg cggtaaggat atcttctaaa catttcgcaa
     2581 tcattctcaa ataatcgatc ttattcatcc gttcctccaa tctgactcca aaccaatcgt
     2641 ccttctacca gtaacccacg aacaaattct cgctggctgg taatatctgt aatgaaataa
     2701 actacatagt cttttccatc ttctggtgcg caataaatat aaagatgtgt catcactaaa
     2761 cgtggtagat gaacatcttt aggaagtgta cctatttcaa tttcctcttt ttccatcgta
     2821 acggattcat agccccactc ttcagaagca gtgaccagct gtgcacactt ttccagtact
     2881 tcgatagccg tttctaacaa gtcctttcgt tcctttcttt tagatactag tattcttctg
     2941 gtaataacat cgtttgatac tcacccgaat caatggccca tattttttga gacactgatt
     3001 tcaaacgaag cttaggtgaa atcagatact cttttctttc ttccggttct tcttgacgat
     3061 gaaccaactt ttgatttcct ttttccgtag aaaattcaaa aatttgaaga tagtctaaag
     3121 gaagttgctt ttgaacgttt tgatcgatta gattccaaca taaagcttgt aattccaccg
     3181 gcaaactgtc cattactccc tttgtgacat aacgttgtcc tttattttga aacatttctt
     3241 ttccctcctt tgctataaaa atagcccaat cttctattaa agaagattgg gcttcatgga
     3301 tataatatat atttgtaaat aaagttaatt cagttataat tatcaaaact acacaattat
     3361 taaagttttt catatctctt tgtttagtaa gtttttctaa atcttaaccc gtggtgctag
     3421 ttaatttttt cctagaggaa aatgtctaaa catgttggta aatcaacaaa aaaacgcata
     3481 tagtagtctc aaaactccca agaaatgagg actatttaac aaactacgat ggttacgtcg
     3541 tgacaactga acattttgac ttagccaatc ctgttactaa agtcgatgat atccccgatt
     3601 atgaaatgta cagtcaaaca atcgatagct taaataagcg ttttggcaat cgtgttttaa
     3661 aaggcatcga aatcggttac atcgcttctg aaaaggatcg gatcatcgac tatttagccg
     3721 ataaagatta cgatttaaaa ttactcagtg tgcatcataa tgggcaattt gattatttag
     3781 atgacgaagt caaagatatg gatcctgcta ttgtgattcc tcagtatttt gcacaacttt
     3841 cagaagcact agttgttata gaagcagatg tctttgctca ttttgactat ggttttcggg
     3901 tatttggtct atccgttgct gaatttaaac aatatgaagc gcagttttta ccgattctag
     3961 atcaagtaat caaaaataaa ttggcattcg aattaaatgc taagagcgct tacttgtatg
     4021 acaatttagc gttatatgaa tatgtcatcg atttatatct ttcacgtggt ggtaccttgt
     4081 ttagtgttgg atcagatggg cattaccttg aacatttccg tttccatttc gatgatcttt
     4141 ttgctctgtt aaaagcaaat ggtgtgacgg aattagcgat ttatcaaaaa ggaaagcgaa
     4201 ttatggttcc attaccagtc taaaaaaacg tcctcagcat caaaagtgag gacgtttttt
     4261 tagatttctt tttctaaaat cggacaaata cgatcttgtt ttcctaaagg aaaatgtttg
     4321 atcccgattt ttttaaatcc atgacgttca taaaaacgaa tacctgcatg atttttttca
     4381 taaacagtca aacgtaaata acgtttttgt ttcgttttag cataacgatt cgcttcatcg
     4441 agtaaccgtt gccctaaccc tttgttttga taatctttga gcagatagag ccgttgaatc
     4501 tctatagcat ctttttcatc attgactttc atataaccaa tgagtatttg atgatcctta
     4561 ataccaataa atttactggt tgactgtgcc aattctactg ccaatatttc agttgtcaat
     4621 tgtgtctgta aatatccttg catatcaagt ggatctgcgc catcgataaa cgattcataa
     4681 aaactgacaa cacttacaac ttgtaaagca tctagatcat cataatctaa atacgctagt
     4741 gtgatttgat tgttcatcta actcctcctt ttgacatagt atactataaa
//
LOCUS       DAFBVQ010000113         4662 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.118, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000113 DAFBVQ010000000
VERSION     DAFBVQ010000113.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4662)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4662)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4662
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.118"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(172..474)
                     /locus_tag="LLC22_002735"
                     /pseudo
     CDS             complement(172..474)
                     /locus_tag="LLC22_002735"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299784.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="LLC22_002736"
     tmRNA           complement(694..1060)
                     /gene="ssrA"
                     /locus_tag="LLC22_002736"
                     /product="transfer-messenger RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00023"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00023"
     gene            complement(1231..2004)
                     /locus_tag="LLC22_002737"
     CDS             complement(1231..2004)
                     /locus_tag="LLC22_002737"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002346978.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Cof-type HAD-IIB family hydrolase"
                     /protein_id="HBK5435939.1"
                     /translation="MSNYRAITFFDLDGTLLDAKSKITPEVAKAMNALKENNVLPVIA
                     TGRTEAEIHSIMEDAGITSAVTMNGSFIRVDGEEIYSQTFSSEECQKMYDHVQLNGHE
                     LSYYNDQKIWCTGHSQTMINAYDFIHSDVPEIDPLGFKENTVNMLLILSQSGDEYYHE
                     HFPELTFYRNGPYSIDTVKKGISKGAGVKRLQKELQLEKVPTFGFGDGPNDFALLEAC
                     DNKIAMGNAYDGLKELSTFITKKNTEGGIVHALKYFDLI"
     gene            2148..2498
                     /locus_tag="LLC22_002738"
     CDS             2148..2498
                     /locus_tag="LLC22_002738"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SdpI family protein"
                     /protein_id="HBK5435940.1"
                     /translation="MIFFSIGILFLIIGSLFRILPSKGNLPFYGYHSPLAAKTDAHWR
                     LAQKTSGNWFFLMGLLMALIGYYLKTSGHTNYFLIEMLLLVFPIMPIFIMTEKKLQKY
                     DLETGGNDNEYFND"
     gene            2479..3195
                     /locus_tag="LLC22_002739"
     CDS             2479..3195
                     /locus_tag="LLC22_002739"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338866.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5435941.1"
                     /translation="MNILMIEDNQSVSEMMQMFFLNEGWEATFKYDGKEGLDAFLENP
                     QHWDMITLDLNLPTLDGMLVGREIRKVSSTVPIIMLTARDSESDQVIGLEMGADDYVT
                     KPFSPLTLIARMKALHRRSELAEAREEAVVSDDHFDIETSHFKMNTKTREAYLDNRPI
                     EGLTPKEFDLLFTLAKKPRQVFSREQLLELVWDYQYFGDERTVDAHIKKLRQKIEKVG
                     PQVIQTVWGVGYKFDDSGVA"
     gene            3195..4643
                     /locus_tag="LLC22_002740"
     CDS             3195..4643
                     /locus_tag="LLC22_002740"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631900.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5435942.1"
                     /translation="MRYLYQQLLAFCGMVALILLIVGVSFTQLTKQTIEENNYQQLFG
                     YAESVEKTTQTYADTLPQFSQDQAFQNALLLTEQVLTEQNVNFIFIDKNERVIYPTNT
                     ALLNFTLTADQWKNLRNGRQEKFTSNKNILGQAQATSYALVPFNLNHEFYGALVVSQP
                     ARNIDNSVRPITLNLFKGFIFSSIVAVIASYAFAAFQVKRINRLRNATKEVTNGNFDV
                     QLPVHDKDEFDELADDFNKMTNSLKESQAEIEEQENRRRQFMADASHEMRTPLTTING
                     LLEGLEYNAIPENQRENAIKLMKNETERLIRLVNENLDYEKIRTNQISMVIKKFNGTE
                     TLKNIVAQLEAKAEAAGDTLTLKAVDDIDVYADYDRFVQIMVNIIQNAIQFTENGQIT
                     ITLEKGYLETIITIEDTGIGMSEQQMKSIWDRYYKVDPSRKNTKYGESGLGLPIVQQL
                     VRLHKGKLEVESELGKGTKFAVRLPDVEIKKE"
BASE COUNT         1551 a          822 c          900 g         1389 t
ORIGIN      
        1 ttataattgg agtggtagtt aattagtgac ttatttttga ttttatagca ctgatactat
       61 aaaatataga tatcatcata ttacacaatc ttaatactaa cttaaaaaat atccctttta
      121 taagtatggt gataaaatcc gttccgggct acctttttta ggtagcctac tttaatcttt
      181 atacctttct ggatcaacga aagtatactt caaatagtca taacgccgat gatcgctccg
      241 tgcgtctggc acatcagtca cgatatcaaa caaaaaatac acatctttct tcattctggt
      301 ttttgttgcc ggaattttaa agtagttctt attagagtaa tagagattga ttaataagct
      361 atcttcgatt gctaaaaaga aaacttctga atcccacacc ttataaaaat ctttgacaaa
      421 tcaattcgaa ggatcaaatt taaaccataa ttgtgttttt ccttccatca acataatgtt
      481 cacctcaaaa agagtatacg aactaatgtt ctttttgtaa agtaggaata tcattgataa
      541 tatggatgga acatatatat taaaaagtgt tctttttgaa tgctattttg aatgccattt
      601 tcattcattt aacgaaaatc tgcgaaaata aaaaatgctc aaacccttat aaaataagga
      661 tttaagcatc tagcgaaatc tgctgaaatc tcacaatgga gacggcggga gtcgaacccg
      721 cgtccaaaca catcgccact taaaaatcta cgttcatagt caactcattt aaggattcac
      781 tttacagctt gccgagtgac aggcattctg tatcgctagt ctgatgttct ctttttcaac
      841 ttacagacgg aaagttgaaa cgtatcccac taaagttagg acccttactc gagcacatgg
      901 gcgatgccga gaggatctac gctaactgtt tttaggcagc taaagcgtaa gagttgtttt
      961 cgtttttagc agttatattt aactgtaacg tttttacgta gacgtaacct acgaaacgca
     1021 attcaagctc gactgtgcct gtcgaatccg taacgtcccc gttagctaac aagggttacg
     1081 tgtatttttc atacaaaatt agtatagcat atattgggat aaattcaata aaaaagcgaa
     1141 tcatatccca ttatttatat aataactgcc cctttcttaa gaaaaaataa gcgattttct
     1201 taagaaaaga ggtagcttca aaaaaagatc ttaaatcaga tcaaaatact tcaatgcgtg
     1261 gacaattccg ccttctgtat ttttctttgt gataaaggta gaaagttctt ttaatccgtc
     1321 ataggcgttg cccatagcga ttttgttgtc gcaagcttcc aacaaggcaa aatcattcgg
     1381 accatcgcca aatccaaaag taggaacttt ttccagctga agttcttttt gcagacgttt
     1441 gacacctgcc ccttttgaga ttcctttctt cactgtatcg atcgagtaag gaccattccg
     1501 ataaaaagtt agctcaggaa aatgttcgtg atagtattcg tcacctgatt gagataagat
     1561 cagcaacata tttactgtgt tttctttaaa gcctaaagga tcaatttccg gaacatctga
     1621 atgaatgaag tcgtaagcat tgatcattgt ttggctatga ccggtacacc agattttctg
     1681 atcgttatag taagaaagtt catgaccgtt caactgtaca tgatcataca ttttttgaca
     1741 ttcttctgaa gaaaatgttt gagaatagat ttcttcgccg tctactcgaa tgaaagaacc
     1801 attcatggtg accgcagaag taatgcccgc atcttccatg atagagtgga tttctgcttc
     1861 tgtacgtcct gtagcgatga cggggagaac attgttttct tttaatgcgt tcatagcttt
     1921 tgccacttcg ggtgtgattt ttgatttcgc atctagtaat gttccatcaa gatcaaagaa
     1981 agtgattgca cgataatttg acacaaataa aactcctttt ttattggaat aagtttatct
     2041 taacaaagaa tgaacaaaag acaaaccttt cgtgaagaat tcctgaacat attggttcag
     2101 tcaacaattt agagtatact ataagaagag aatttaggag ggaaagaatg atttttttca
     2161 gtattggtat cttattctta ataattggca gtctttttcg gattctgccc tcaaaaggaa
     2221 atctgccttt ttatgggtat cattcgcctc ttgccgcaaa aacagacgct cattggcggc
     2281 tggctcaaaa gacaagcgga aactggtttt ttcttatggg cttactgatg gcattgatcg
     2341 gctattattt aaagacatct gggcatacga attattttct gattgaaatg cttctgctag
     2401 tatttccaat tatgcctatt tttattatga cagaaaagaa attacagaaa tatgacctgg
     2461 aaactggagg gaacgataat gaatatttta atgattgaag ataatcaatc tgtttctgaa
     2521 atgatgcaga tgtttttctt aaatgaaggt tgggaagcaa ctttcaagta tgatggaaaa
     2581 gaagggctcg atgccttttt agaaaaccca caacattggg atatgattac actagacctg
     2641 aatttgccca cactggacgg tatgctagta ggaagagaga tccgcaaagt ttcaagtact
     2701 gtgccgatta tcatgctgac agctagagat tctgaaagcg atcaggtgat cggcttagag
     2761 atgggggcag atgattatgt cacaaaacct ttcagtcctc tgacgcttat tgctcgaatg
     2821 aaagctttgc atcgccgtag tgagttggca gaagcaagag aagaagcagt agtttcagat
     2881 gatcattttg atatcgagac tagtcatttc aagatgaata cgaaaacacg agaagcgtat
     2941 ctggacaacc ggccaattga aggactgacg cctaaagagt tcgatctatt gtttacttta
     3001 gcaaaaaaac cacgtcaagt attctctcgg gagcagttgc ttgaattagt ctgggattat
     3061 cagtactttg gtgatgaacg gacagtggac gcccatatca agaaattacg acaaaaaatc
     3121 gaaaaggtcg gaccacaagt catccaaact gtttggggag tcggctacaa attcgatgat
     3181 tctggtgttg cctaatgcgt tatttgtatc agcaactctt agctttctgc ggaatggtcg
     3241 cgttgatctt attgatcgtt ggagtttctt ttacacaact gacaaaacaa acgattgaag
     3301 aaaacaatta ccagcaactg tttggatatg ctgaatcagt tgaaaagaca acgcaaacct
     3361 atgccgatac gctcccgcag tttagtcaag atcaggcgtt tcaaaatgca ttgctgctga
     3421 cagagcaagt actgacagaa caaaatgtga actttatatt tatcgataaa aacgaacgtg
     3481 tcatttatcc gactaataca gctttactga attttacctt aacagctgat caatggaaaa
     3541 atctgaggaa tggacgtcaa gaaaaattca catcgaataa aaatatttta ggacaagcac
     3601 aggcgacctc ttacgcactt gtgccattta atttgaatca tgaattctat ggagcacttg
     3661 tagttagtca acctgcgcga aatatcgata acagcgttcg tccaattaca ctgaacctgt
     3721 tcaaaggatt tattttttcc agtatcgttg cagttattgc cagctatgct tttgcagcat
     3781 tccaagttaa gcgtatcaat cggttaagga atgcgacgaa agaagtgacg aatggtaatt
     3841 ttgatgtaca gctccccgta catgacaaag atgaatttga tgagttagca gatgatttca
     3901 ataaaatgac gaattcattg aaagaatctc aagcagaaat tgaagaacaa gaaaatcgtc
     3961 gaagacaatt tatggcagat gcttctcacg agatgagaac acctcttacg acaatcaacg
     4021 gacttctgga agggttagaa tacaatgcaa tccctgaaaa tcagcgagaa aacgcgatta
     4081 aattgatgaa aaatgaaaca gagcgtctga tccgtttggt gaatgaaaac ttggattatg
     4141 aaaaaatccg tacgaatcaa atcagtatgg tcattaaaaa attcaatgga acagaaacat
     4201 tgaaaaatat tgttgcacag ttagaagcta aagcagaagc agcaggagat acattgacat
     4261 tgaaagccgt tgatgatatt gatgtttacg ctgattatga ccgatttgtc caaatcatgg
     4321 tcaatattat tcaaaacgcg atacagttta ctgaaaacgg ccaaatcacg attactttag
     4381 aaaaaggcta tcttgaaacg atcatcacga ttgaagatac gggaattgga atgtctgaac
     4441 aacaaatgaa aagtatctgg gatcgttatt ataaagtaga tccttcaaga aaaaatacaa
     4501 aatatggtga atcaggatta ggtttaccaa tcgtgcagca acttgtacgc ttgcataaag
     4561 gaaaattaga agtagaaagc gaactaggaa aaggaacaaa attcgctgtt cgtttgcctg
     4621 acgtagaaat caaaaaagag taaaaaacaa gcggtataaa ag
//
LOCUS       DAFBVQ010000114         4616 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.119, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000114 DAFBVQ010000000
VERSION     DAFBVQ010000114.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4616)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4616)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4616
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.119"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(15..962)
                     /locus_tag="LLC22_002741"
     CDS             complement(15..962)
                     /locus_tag="LLC22_002741"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368530.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoglycerate dehydrogenase"
                     /protein_id="HBK5435943.1"
                     /translation="MSERIIYADRPFRDEFIEEIHTIAPGYIFKTELQPEDLQNVEIS
                     LGWNSDYQEKLLASSTLKWVQSISAGVDQLPLETFSKKHILLSNGSGIHSESITEHVL
                     GIILGYSRGLFQAQKAQSDMKWLGSSVHYQSIQGKKILIIGTGHIGKMIAKKCKALDM
                     NCYGINTSGHPAEGMEKTFSLNQLKEVLPEVDFVVNILPLTEETTGLFDQHMFEHFDP
                     KSVFINVGRGASVKTQDLVQALNNQQLSFAALDVFEEEPLPQDHPLWKMDNVLITSHI
                     AGLTPDFQKKLMAIFLTNLKSYFATHELQTNQVKLSAGY"
     gene            complement(1140..1943)
                     /locus_tag="LLC22_002742"
     CDS             complement(1140..1943)
                     /locus_tag="LLC22_002742"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323479.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1189 domain-containing protein"
                     /protein_id="HBK5435944.1"
                     /translation="MTTKQLIISSFIRFKDLKEARNVPFWKAIVYLLVLSIIMALPIS
                     FQVFQVLNNIQLDGQKIATRIPDFTIQNGQLQTEEKEGFIYQTNSIIFTFDPEGKRTE
                     QDISTDLMGNFVSVGMLKNKLIIALPNTGTTSALLNNNQLELPYTNESLKNLTGKQLR
                     SFLSEASIPLWIKVLTFIFSIYPSFLNLLITLLFTNIAAFLYARFRLTKATFLDCLKT
                     LIYSISLPTIIATILMVFLPSFDTSAFIAFAGIFIFAQAVKGWAKISIN"
     gene            2089..3003
                     /locus_tag="LLC22_002743"
     CDS             2089..3003
                     /locus_tag="LLC22_002743"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cation transporter"
                     /protein_id="HBK5435945.1"
                     /translation="MEEGIVPTQPQRSSKKLFGVVVLNAVITLSEFIGGIMSGSLSLV
                     SDAFHNLSDTLAIIFSYGAQKMARKEANKKRTYGYQRLEILSAFINSFILIILSLFLT
                     VEAFKRFTSPEKINSHLMLTVAVIGLLANLFSVLLLRQEADESLNIKSSYLHLLSDTL
                     SSVSVIIGAILIRFFDIYWIDPVITLIISIYILIEAIMVIKKAAAILIQSAPAIDYEK
                     MEQEIEAIDGVKDVHHVHIWQYSEKIIIFDGHIDFEDQLLSEIEKIYPRIISLLKLKY
                     GITHVTIQAETKAKDQKKLIFLNKDESY"
     gene            3051..3521
                     /locus_tag="LLC22_002744"
     CDS             3051..3521
                     /locus_tag="LLC22_002744"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318629.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GtrA family protein"
                     /protein_id="HBK5435946.1"
                     /translation="MKQYRQLKGYLEAKGYWEILVYLFFGGLATIVNFVSFALARQYF
                     DLSMALSNSISWFCSVLFAFVTNKLWVFHSKSPNFTHALIECGKFFFYRILSYGLDMG
                     AMVLLINVMNSNEYVAKIITQIIVILANYIFSKLFIFKETEVFEEEVGQSEKDD"
     gene            3606..4214
                     /locus_tag="LLC22_002745"
     CDS             3606..4214
                     /locus_tag="LLC22_002745"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298541.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="superoxide dismutase"
                     /protein_id="HBK5435947.1"
                     /translation="MTYTLPDLPYAYDALEPYIDEETMHLHHDKHHNTYVTNLNSAIE
                     KYPELGEKTIEELLSDMDAIPTDIKTAVRNNGGGHANHSFFWEIMAPNAGGEPTGEIK
                     EAINEAFGDFSSFKEEFKKAAAGRFGSGWAWLVMENGKLAITSTANQDSPLMEGKTPI
                     LGLDVWEHAYYLKYKNVRPDYIAAFWNVINWDEVNKRFEAAK"
     gene            4348..4548
                     /locus_tag="LLC22_002746"
     CDS             4348..4548
                     /locus_tag="LLC22_002746"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003230776.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5435948.1"
                     /translation="MEHGTVKWFNNEKGFGFITVDGGDDVFVHFSAIQGDGFKSLEEG
                     QEVEFTIVEGARGPQAAEVTKL"
BASE COUNT         1511 a          716 c          912 g         1477 t
ORIGIN      
        1 attgttttca gctattaata tcctgcagac aattttactt gattggtttg aagctcatgg
       61 gtggcaaagt agcttttcag attggttaaa aaaatagcca ttaatttctt ttgaaaatca
      121 ggtgtcaaac ctgcaatgtg ggaagtaatc agtacattgt ccattttcca aagaggatga
      181 tcttgtggaa gaggctcttc ctcaaaaacg tctaatgctg caaaggaaag ttgctggtta
      241 tttaaagcct gcaccagatc ttgtgtctta acagaagcac cacggccaac attgatgaat
      301 acagattttg gatcaaagtg ttcaaacata tgctgatcaa agagcccagt tgtttcctcc
      361 gttagaggta agatattgac tacgaaatct acttcaggaa gaacttcctt tagttgattt
      421 aaagaaaaag tcttttccat tccttctgct ggatgaccgg atgtattgat tccatagcag
      481 ttcatgtcta atgctttgca tttttttgca atcatttttc caatatggcc agttccaatg
      541 attagtattt ttttcccttg gatagattgg taatggaccg atgaacctaa ccatttcatg
      601 tcactctgtg ccttttgtgc ttgaaaaaga ccacgagaat acccaaggat gattcctaag
      661 acatgctccg taatcgattc actgtggatg ccactaccat ttgaaagtaa aatatgtttc
      721 tttgaaaaag tctcaagggg tagctgatca acaccagctg agatagattg gacccatttc
      781 aaggtagaag aggctaatag tttttcttgg tagtctgagt tccagcccaa actgatctct
      841 acattttgta gatcctctgg ttgtaattct gttttaaaga tataaccagg cgctatagta
      901 tggatttctt cgataaattc atcacgaaat ggacgatctg cataaatgat tctttctgac
      961 atagttaatt tcccgccttt ctttactcta agtgtagcgc atacaagaag aactttgaag
     1021 cgccttgctt gttttttgag aaagaaatat ttttcaaata aaaaaggggc tgtgacaaaa
     1081 aaatgtcaca acctctaaaa gggtctattg aagtagaaat aacgagttgt ctttatttct
     1141 taattgatcg atatttttgc ccatcctttg acagcttgag caaaaataaa gattcctgca
     1201 aaagcaatga aggcgctagt gtcaaaagaa ggaagaaaga ccatcaagat tgttgcaatt
     1261 atagtaggca atgaaattga atagatcaat gtttttaaac aatcaagaaa agtagctttt
     1321 gttagtcgaa agcgtgcata gagaaaagca gcaatgttgg taaatagcaa agtgatcagc
     1381 agattcagaa aactaggata aatagaaaat ataaatgtca ggacttttat ccaaagtggt
     1441 atagatgctt cacttaaaaa agaacggagc tgcttacctg ttaagttttt taaagattca
     1501 ttggtgtagg gaagttctaa ttggttattg ttcaacaaag cagaagtcgt gcctgtatta
     1561 ggaagagcta tgataagttt gttttttaac atcccgacac taacaaaatt ccccatcaaa
     1621 tcagtagaga tgtcctgttc tgttcgtttt ccctctggat caaatgtgaa gataatggag
     1681 tttgtttggt aaatgaatcc ttctttttct tcggtttgaa gctgcccgtt ttggattgta
     1741 aaatcaggaa tgcgagtagc aatcttttgc ccatccaatt gaatgttgtt taagacttga
     1801 aaaacttgaa aagagattgg caaagccata attatactca aaactaaaag atagacaatg
     1861 gctttccaaa atgggacatt tctcgcctcc tttaggtctt tgaatcgtat aaaggaactg
     1921 ataattaatt gttttgttgt cataagtact cctcatctag tagtgtcatc acttgcaatt
     1981 ctagcgaagt atcaagtgaa atacaagtgc tttaaggaaa cagctgaatg attggtgaaa
     2041 tatcaaaaaa atgttattct tgtctaaaga ctatccaata taaataaaat ggaggaagga
     2101 atagtgccta cacagccaca gagatcatca aaaaaactat ttggagtagt ggttttgaat
     2161 gcggtgatca ctttatcaga atttattgga gggattatgt cagggagttt gtctcttgtt
     2221 tcagatgctt tccataacct tagtgataca ttggcaatta ttttttctta cggggcacaa
     2281 aaaatggccc gaaaagaagc aaataaaaaa cgtacgtatg gctaccagcg tttagaaata
     2341 ttgagtgctt tcatcaactc attcatattg atcatattat ccttgttttt aaccgttgaa
     2401 gcattcaagc ggttcacttc accagaaaag ataaatagtc atttgatgct aacagtagca
     2461 gttattggat tgctcgcgaa tttgttctca gtattattat tacgacaaga agcagatgaa
     2521 agtttgaata taaaatctag ttatttgcat ttgttaagtg atacactgtc ttcggtaagt
     2581 gtgattatcg gagcaatttt gatccgtttt ttcgatatct actggatcga tccagttatt
     2641 acactgatca tttcgatata tatattgata gaagcgataa tggtgatcaa aaaagctgcc
     2701 gctattttga tacaaagtgc acctgctatc gactatgaaa aaatggaaca agaaattgaa
     2761 gcaatcgatg gggtaaagga tgttcatcat gtccatattt ggcagtatag cgaaaagata
     2821 attattttcg acggacatat tgattttgaa gatcagctac taagcgagat tgaaaagata
     2881 tatcctcgta taatttcttt attaaaatta aaatatggta ttacacatgt gacgatccaa
     2941 gcagagacaa aggcaaagga tcaaaaaaaa ttaatttttt taaataaaga tgaaagttat
     3001 tgaaatatag agtatgataa ataagaattt ttaataaggt aggttggctc atgaagcagt
     3061 atcgacagtt aaaaggatat ttagaagcaa aaggatattg ggagatacta gtctatctct
     3121 tttttggtgg tttggctacg attgtaaatt ttgttagttt tgctctcgca cgccaatatt
     3181 ttgatttaag tatggcctta tccaattcta tttcgtggtt ttgttctgta ttgtttgctt
     3241 ttgtaacgaa caaactttgg gtattccatt caaaatcacc gaattttaca catgcactta
     3301 ttgaatgcgg taagttcttc ttctaccgta tcctttctta cggattggac atgggggcaa
     3361 tggtattgtt gatcaatgtt atgaacagca atgagtatgt ggcgaaaatc atcactcaaa
     3421 ttattgttat ccttgcgaac tatattttca gcaagttgtt tatttttaaa gaaactgagg
     3481 tttttgaaga agaagtaggt caaagtgaaa aagacgacta ggcataacaa ttgaagaatt
     3541 tccttctctt tgttactctt tgtaatgtag acattattaa gaaaacattg aggaggaatt
     3601 tttttatgac ttacacatta ccagatctac cttatgcata tgacgcattg gaaccttata
     3661 ttgacgaaga aacgatgcat ctgcatcatg ataagcatca caatacttat gtgacgaatt
     3721 taaattcagc aattgagaaa tacccagaat taggcgaaaa aacaatagaa gaattattat
     3781 ctgatatgga cgctattcca acagatatca agacagctgt acgtaacaat ggtggcggac
     3841 atgctaacca ttcatttttc tgggaaatca tggcaccaaa tgctggtggc gaacctacag
     3901 gagaaataaa agaagcgatt aatgaagctt ttggtgattt ttcttctttt aaagaagaat
     3961 tcaaaaaagc agccgctgga cgatttggtt ctggatgggc ttggcttgta atggaaaatg
     4021 gaaaattagc tattacctct actgcaaatc aagattctcc attgatggaa ggaaagacac
     4081 caattctagg tttggacgtt tgggaacatg cttattattt gaaatataaa aatgtccgac
     4141 cagattatat tgcagcattc tggaatgtta ttaattggga tgaagtaaac aaacgtttcg
     4201 aagcagcaaa ataaccattt cctccgtcat atcagtctta aaaataattt ggaaaataaa
     4261 agagcgaaag cttgctagcg ttttctaaat tgggtataat gttcttgcaa ggttacttgc
     4321 aagaactttt ttggaggata tacatttatg gaacacggaa cggttaaatg gttcaacaat
     4381 gaaaaaggat ttgggtttat tacagtagac ggcggagatg acgtatttgt tcatttctca
     4441 gcaattcaag gagacggctt caagagccta gaagaaggtc aagaagtaga attcacgatt
     4501 gttgaaggtg cacgcggacc tcaagctgct gaagtgacta aattataata atttgttgaa
     4561 taaagacacg acttcttaga gagtcgtgtc tttttgtcta tttatgaagt ttttag
//
LOCUS       DAFBVQ010000115         4551 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.120, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000115 DAFBVQ010000000
VERSION     DAFBVQ010000115.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4551)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4551)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4551
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.120"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            591..1280
                     /locus_tag="LLC22_002747"
     CDS             591..1280
                     /locus_tag="LLC22_002747"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5435949.1"
                     /translation="MKILIADDDKEIVELLSIYVHNEGYEAVKAYDGKEALSKIRTIP
                     DIELLILDIMMPEMDGMQVVKELRKESQIPIIMLTAKTTDMDKIKGLVAGADDYVTKP
                     FNPLEVMARVKSLLRRTKMQIAPDQPDVLEVNALIINKDSHEVKTIDGKEIQLTALEF
                     GILYLLASHPNRVFSADEIFERVWKQESIVSAKTVMVHVSHLRDKIEEATGGEKVIQT
                     VWGVGYKIDAR"
     gene            1267..2475
                     /locus_tag="LLC22_002748"
     CDS             1267..2475
                     /locus_tag="LLC22_002748"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330803.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5435950.1"
                     /translation="MTQDSKRATEKRRRINLTSKEISELLAEGIITIILLLLLNVSIL
                     VVISSVINSSPSLTNAIWDSKNIFAERLNTDLFWNGRNFIIPFFFLLDIGVLYWRLIR
                     RYRQMQLRHIISELHYIANGNYDHRIPFELSGDLSRVVTSINGLVDSTVAAIEDERKI
                     EKSKDELITNVSHDIRTPLTSIIGYLGLIEDGQYHSEEDLLKYTHTAYIKAKQMKSLV
                     DDLFEYTKVRQPAVPVNFSAFDMIQLIEQLAADFELEASKKNIQILVQSKVDSLIMDG
                     DTEKLVRVFNNLLTNALKYGKGATKIVIEVERIGSEVVATVKNNGAMIPQQAIDNLFD
                     RFYRVEESRSQATGGTGLGLAIAQSIVALHGGYIYAKSDKQWTSFIMHLPIKKNEKLP
                     IDTQEVIDES"
     gene            2769..4040
                     /gene="serS"
                     /locus_tag="LLC22_002749"
     CDS             2769..4040
                     /gene="serS"
                     /locus_tag="LLC22_002749"
                     /EC_number="6.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002338634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="serine--tRNA ligase"
                     /protein_id="HBK5435951.1"
                     /translation="MLDVKMMRQNIEEVQEKLMTRGVKKETLAEFMELDENRRKLLVK
                     SEELKKYRNDVSAEIAQLKRAKEDASAKIAEMKEVGGNIKALDTEIAEVDEKLKQIAT
                     TLPNLPHDSVPVGTDEEDNVEIRRWSEPRTFAFEPKPHWEIAENLDILDFERGAKVAG
                     SRFVYYKGLGARLERAVYNFMLDQHIYEHGYTEMITPYIVNSKAMFGTGQFPKFKEDV
                     FQLENTDLTLIPTAEVPLTNYYNDEILDGADLPIYFTALSPAFRSEAGSAGRDTRGLI
                     RLHQFNKVEMVKFSDVEHSYEELEKMTADAEDILKKLHLPYRVMALSTGDMGFSAAKT
                     YDLEVWIPAQDTYREISSCSNCEDFQARRAMIRYRDNDGKIHYTHTLNGSGLAVGRTV
                     AAILENYQNEDGSVTVPEALVPYMGNLKVIK"
BASE COUNT         1475 a          784 c          909 g         1383 t
ORIGIN      
        1 ggagtgtttc ccgattcgtt tttggctgcc gtagcaactt ttatatcata tcagagagac
       61 aagtaattgt caactctttt ttaaaagttt tttcgatttc gtttttcgaa atcttccagc
      121 aactcattta tcataactta tcgtttgtta tttgtcaaga acttttttga agtttttttc
      181 gatagaatca agcttcgcaa gtggttcttt tttaacgact cagttatctt atcatgtcat
      241 ttccaacatg tcaacaactt attttttatt atttaataag ttattggtgt tcttttgaac
      301 aaataataat atatcaacat cacatgtgaa agtcaataag aaaatgctta tttatcaaca
      361 tttctagctt acatgatcat tggttagttc tggtcctttt tcgttcgtct ttataactcc
      421 gagagacgta aaatcctttt gttttcagtt taatgttcat gttcttgtct tattcacacc
      481 aactagatgt ctcaccttct aaaattttcc ttaacaaagt gctgctttta tctatttctg
      541 cttttttttg ctagaataat agtaacaata tgactctgga ggatttattt atgaaaattt
      601 tgattgctga cgatgataaa gaaatcgttg aattattaag tatctatgtt cacaatgagg
      661 ggtatgaagc agtaaaggct tatgatggga aagaagcatt atctaaaatc agaacaatcc
      721 ctgatattga attacttatt ttagatatca tgatgcctga gatggatggg atgcaagtag
      781 tgaaagagct acgaaaagaa tcccaaatac caatcattat gctgacagca aaaactactg
      841 atatggataa gatcaaagga ctggtcgctg gtgcagatga ttatgtgacc aagccattta
      901 atccgttaga agtaatggct agagtaaagt ctttattacg gcgtacaaaa atgcagattg
      961 ccccagatca gcctgatgta ttagaagtaa atgcattaat catcaataaa gactctcatg
     1021 aagttaaaac aatcgatggg aaagaaatcc agttaacagc tttggaattc ggtatcctct
     1081 acttgcttgc tagtcatcct aatcgagtat ttagcgcgga tgaaattttt gagcgtgttt
     1141 ggaaacaaga aagtattgtc tctgctaaaa ctgtcatggt tcacgttagt catttaagag
     1201 ataagattga agaagcaact ggtggtgaaa aagtcattca aaccgtttgg ggagtgggct
     1261 ataaaattga cgcaagatag taaacgagca actgaaaaac gccgtcggat caatttgact
     1321 tcaaaagaaa tcagcgaatt gttagcggaa ggaatcatca cgattatcct tttgcttcta
     1381 ttaaatgttt ctattctggt tgttatcagt tcggtgatca acagttcacc ttctttgacg
     1441 aatgcgattt gggattcaaa gaatattttt gcagaacgat tgaacactga tttgttctgg
     1501 aacggccgga attttattat tccctttttc tttctattag atattggtgt tttgtattgg
     1561 cgcttgattc gaagatatcg ccaaatgcaa ttgcggcata tcatcagcga acttcactac
     1621 atcgcaaacg gaaattatga tcatcgtatc ccttttgaac tgagtggtga cttaagccga
     1681 gtggtaacaa gtatcaatgg attggtggat agtaccgtag cagcgattga agacgaacgt
     1741 aaaatcgaaa aatcaaaaga tgaattgatc acgaatgtca gtcatgatat ccgtacccca
     1801 ctcacgtcca tcattggata cctaggactg atagaagatg gccagtatca ctcagaagaa
     1861 gatcttttaa agtatacgca tactgcttat atcaaagcaa agcagatgaa atctttagtg
     1921 gacgacttat ttgaatacac taaggtacgc cagcctgctg tcccggtgaa tttttctgcc
     1981 tttgacatga tccagttgat cgaacagtta gcagctgatt ttgagttgga agcttctaaa
     2041 aaaaatatcc aaatacttgt tcaatcaaaa gtagactccc ttatcatgga tggcgatacc
     2101 gaaaaacttg tacgtgtctt caataatctt ttgacgaatg cgttgaaata cggaaaagga
     2161 gcaacgaaga tcgtaatcga agtagaacgt atcggttcag aagttgttgc aacagtcaaa
     2221 aataacggag caatgatccc acaacaggca atcgataatc tattcgaccg tttttatcgt
     2281 gtagaagaat ctcgttcaca agcaactgga ggaactggac ttggtttagc aatcgctcaa
     2341 agcattgtgg ctttgcacgg cggatacatt tatgcaaaat cagataagca atggacttct
     2401 ttcatcatgc accttccaat caagaaaaat gaaaaattac ctattgatac acaggaagtt
     2461 attgacgaaa gctgaaatat tcgctattct tattacaatt attagaataa atgaaaaaca
     2521 cagaacccag tacactttat tctttttcag agagctgatg gcaggtgtaa atcagcaaag
     2581 gataatttgg aagttccagt tcgtttacgt gccctttcga aataagaaag gtcggttcaa
     2641 cagccgttat gtgttcaaca agtgcagctg acgctgaact tgggtggtac cgcgaatttc
     2701 agactgattc gtcccaagaa taatgggatg gatcagtctt tttttatttt caaaaaggag
     2761 gaaatcatat gttagatgta aaaatgatgc gacaaaatat tgaagaagta caagaaaaat
     2821 tgatgactcg gggcgtaaaa aaagaaacat tagctgaatt catggaacta gatgaaaatc
     2881 gtcgtaagct actagtcaaa agtgaagaat taaaaaaata tcgaaatgat gtttctgctg
     2941 agatcgccca attgaagcgt gcaaaagaag atgcttctgc taaaatcgct gaaatgaaag
     3001 aagtcggtgg caacatcaaa gcattggata ctgaaattgc tgaagtggat gaaaaattga
     3061 aacaaattgc aactactttg ccaaaccttc cccatgattc tgtgccagtt ggaacagatg
     3121 aagaggacaa tgtagaaatc cgtcgttgga gcgaaccacg tacatttgct tttgaaccaa
     3181 aaccacactg ggaaattgca gaaaatcttg atattttaga ttttgaacgt ggcgcaaaag
     3241 tagccggtag ccgttttgtc tattacaaag gattaggtgc tcgattagaa cgtgctgtct
     3301 acaacttcat gcttgatcag catatttacg aacacggcta tactgaaatg atcactcctt
     3361 atatcgtcaa cagtaaagcg atgtttggta cgggacaatt tccaaaattc aaagaagatg
     3421 ttttccaatt ggagaatact gatctaacat taatcccaac agctgaagta ccattaacta
     3481 actattataa tgatgaaatt ttagatggtg cagatttacc tatttatttc actgcactaa
     3541 gccctgcttt tcgttctgaa gccggaagtg ctggtcggga tacacgagga ctgattcgtc
     3601 ttcaccaatt caataaagta gaaatggtca aattttcgga tgtagagcat tcttacgaag
     3661 aattggaaaa aatgacagct gatgcagaag atatcttgaa aaaattgcat ttgccttatc
     3721 gtgtgatggc cttatcaact ggagacatgg gcttttctgc agctaaaact tatgacttag
     3781 aagtatggat acctgcacaa gatacttatc gtgaaatcag ttcttgttct aactgtgaag
     3841 atttccaagc acgccgcgca atgatccgtt atcgcgataa tgatggaaaa atccactata
     3901 ctcatactct gaatggttca ggacttgcag ttggccgtac agtagctgcc attttggaaa
     3961 actaccaaaa tgaagatggt tctgtcacag ttccagaagc gctcgttcct tatatgggga
     4021 atctgaaagt tattaaataa agaggctgtg aaaaagccgc ttagtttcga gtattaagaa
     4081 aaattttgtg aaaatggctt tccacatttt tgcataaatt ggacttaata ccgagaaact
     4141 ggcttttgaa caccatttat cgagaggttg tgaaatcagc gaattaacct gagtattaga
     4201 gaaaaaaatg gaaaaatagt ccctcatatt ttaccgtttg ttgaactaat accgagggtc
     4261 agctgattga acaccgttta gtggagaggt cgtaagccta ccccccagct cctagttaca
     4321 aggacaaatt caaaaaacag ctcttcatat tttatgaatg ttgtacttgt gattcggagg
     4381 tggcaaggga acactgttta ttcaaaaaga ggctgggaca gaagcgttta actccaagaa
     4441 ataagaagaa attcacgaaa attgcttttc aaatttttgt gaatttcttc ttatttccga
     4501 aggagttgct tctacttccg ccgtttatac gtgtttagag cgtgagacaa a
//
LOCUS       DAFBVQ010000116         4462 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.122, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000116 DAFBVQ010000000
VERSION     DAFBVQ010000116.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4462)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4462)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4462
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.122"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(306..836)
                     /locus_tag="LLC22_002750"
     CDS             complement(306..836)
                     /locus_tag="LLC22_002750"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5435952.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
     gene            complement(1018..1674)
                     /locus_tag="LLC22_002751"
     CDS             complement(1018..1674)
                     /locus_tag="LLC22_002751"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBK5435953.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            complement(1801..2274)
                     /gene="dfrF"
                     /locus_tag="LLC22_002752"
     CDS             complement(1801..2274)
                     /gene="dfrF"
                     /locus_tag="LLC22_002752"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBK5435954.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            complement(2693..2911)
                     /locus_tag="LLC22_002753"
                     /pseudo
     CDS             complement(2693..2911)
                     /locus_tag="LLC22_002753"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(2942..4156)
                     /locus_tag="LLC22_002754"
     CDS             complement(2942..4156)
                     /locus_tag="LLC22_002754"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBK5435955.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
BASE COUNT         1373 a          944 c          658 g         1487 t
ORIGIN      
        1 gaaatcaact gtctttctca tatttactat tcaattttca tagtgatata ggtacaattt
       61 atatcactac tgtaaaaatg gggttttgcc ttataaatac agcgttttcc gcttgttagt
      121 gtatagtgtt tcttgttttt tgtgcccccc ttgttagata acgggggctt tgaacggctc
      181 gcaagctcgc cgaaccgccg aagcgaaccg cccccttgca agcatggcgg aaaaatctta
      241 aggattttcc cgccaacgtg gtcggatcgc tccgtcggtt taacagcttt tctgtttctc
      301 tctagttatc tacgcatata aatcaaatcg gttattccgt tataagtctg tgttttacaa
      361 agccttaact ttatttccct gtctatgttg cccaaaagac gaaccccatt tcctaacaga
      421 gtaggaataa cagaaatgta atatttatca atcatatttt tgcttaccaa ctgctgaaca
      481 agatttgctc cgccacaaat ccaaatatcc tttcctgctt cttgttttag ccgttccaat
      541 aataaaacag gattttcact tgtaaaatga atttgttggg aagaattgca ctctttatgt
      601 gttaatacat aagttgtaaa tttattatat acccattctt gcggagaaag ttcagtaaca
      661 acctgatgag aagtattcca ccccattaag acagtatcta tatctttggt aaattctgta
      721 taagtgtcga tgttttcatt gtcatttcca tgaccattta gccaagctac tccaccatta
      781 ccgtccgcaa tatatccgtc aaggctcatg gcaataaata aaactacttt tctcattttt
      841 tctcttttat aaatacaaac aggaatttat ttctcttttt tactcataag ggaacaactg
      901 attgctacaa ataaacccat taaaatccat ggaaatgctg ctcttataaa atcactaacc
      961 atactttatt cctccttaaa ttccaatttc cttagttcta caaactgaaa tttttgccta
     1021 tgaatgtatc ttgttcttta tacgcaaaca ggcttctgtg tgcataatcc aatgtcttga
     1081 aaacggcatt tgaattagtc cacaaatatc tttattacac caataatcaa tcagccaaat
     1141 tgctttttca ttgtcgttta ctacattcaa cgattctaag tatccttttc tttctttcgg
     1201 tatttttctt ttcaattcat cataagataa ccgttcaagc attttctcag tgctttccca
     1261 tacttcgaaa atatataaat ataattcttc cagattaagc tgttttgaaa agtctgcaat
     1321 ctgctgtttc atgagttcat ttcctgttgt aatgataggt gaattgatac gctcttgata
     1381 attgcctgca aaaaatactt gttcatcttc atttatcact gtatgcacaa ctatatcttc
     1441 aatgcggaaa atatgccaaa tagaataagc aatcgtctta ctatgataac catcagcgtt
     1501 tatgaagggg attgagttaa aatcttctct gcataattct tctttgaaag atactaaggt
     1561 ttgtattaac tgacttcgta aagtaagtaa agtatcaata cccctcttat aagtatcttt
     1621 cttttttatt tgtgcctgca ttgttttatt aagttcagac cattccttat tcatattcaa
     1681 tcctctctca aattctgatt ttatcgcccc atacaaactg gaatttgtct tacaacaatt
     1741 tatatatgca taaaaagcaa tatatttatg aaaacaccct aaatccaaaa tttactcaat
     1801 tcattttttc cttacataaa atgttctcgt atatttcact tcctcaccaa gtgtttcccc
     1861 tatcaaaact tcaaaatcat tgatatcaaa ttctggaaag aatgtatctc catcttcaat
     1921 atttaaatct acttctgtga tatacatttt atctactatt tgcaaagctt ccttaaatag
     1981 tccatatcca ccagatatgt atacatctcg tcctttagcc aataataatg catcttctaa
     2041 tgatttaact gaaactaaat tatctccttg atactctgtt gtggtggaaa caacaatatt
     2101 cattctatta ggcaacggat gaccgatttc ttcataagac tttcgcccca taataaccac
     2161 attacccgtt gttaactctc taaattgctt ttgttctccc tttattttcc atggtatatt
     2221 accattcttg cctataacat tattctttga cctcgcaaca atcaaaccta tcatctattt
     2281 catcctccat aatatgatgt cgtacctgtg attccatcaa gtgcaccaca tcttaacaaa
     2341 ctcaaaatta tctcgaacta accagctcga caaattcctt ttttgtcttc atctgcatta
     2401 tatcatattg ttataagcat tgccatttct tttctgcttt tgaaaagtta cttatcagcc
     2461 tatgttttgt aaagggtgat attcagcatt tctcacgcaa caagcccttg acaaaccata
     2521 gactaataag ttttaaggta atcaagcaga aatgaaatag tctgctgttt cacggcaaca
     2581 aaaaagagat accaacacac ttatgtagta tctcttagtc tagtagcaat attcttttgt
     2641 ttgcaagcag gtaaacatgg gctgtttctt aatatctttt tgtttgggaa acaccttttt
     2701 cccatccttt caccgttgcc atctctgctg cgcacaatgc cacagggata aaccatagca
     2761 aaccgcctaa taacaagaaa aatactaagc tgaagcctga ggtcgcgaat gtgggatatt
     2821 catataatga aacgaccatt gagatggtca tagccaaaaa gccaaagaac gttaattttt
     2881 ttgcaggaat tttcgttttg ctttgttgca tgaatcttcc tcttttctat ttgaatttgt
     2941 ttcaattgag tttgttgcca aagaagaaaa agtccaatcc ttcttcttgt tcttcttttg
     3001 tagtagtgat cgttgtaaag tgcatcgccg attttaaaat cactgttgtc agcacatagg
     3061 catacacggc agtaatgatg acaccaatca cttgaatccc taagaagtac cagctgcttg
     3121 gattcgttag taaatggctg ttagatgcaa agatccctat cagaatcgta cctgtgaatc
     3181 cgcccatgcc atgaacaccc cacacatcaa gtgcatcatc ccattgtttc tttttacgaa
     3241 aatcaacagc agcatgacag acgatacccg caatgatccc aatcagcatg gcactttttg
     3301 cttctacata accggcacaa ggcgtaatgg ctgccaatcc agcaacggat cctgttagta
     3361 cgtcgacaaa atcaaagcca tttcctttta cttttgcaat gatcagccaa gtaatcatcg
     3421 caaatgcaag agcgatgaat gttgaaccaa atgcattgac tgcttgttca tctgctcgaa
     3481 gtgcaccacc ggaattaaaa ccgaaccagc caaaccaaag cagtcctgta ccgatagcag
     3541 ctgccataag actgctatgc tgacttcttt ctcctaaagg aatctttctt tgaccaagtg
     3601 tgaggataca tgctaaagag ccgaatccag ctgtcgtgtg gatgactgct ccaccagcga
     3661 aatctctaaa tcccatctga tccaaaaatc cgccacccca tatccagtgg caaacaggga
     3721 aataaatcag cagattccaa aaaataacaa gtataatata gccttttaaa ttcaatctcc
     3781 ctgcaaaagc tcctgtcatc aaaggaacgg taatcacgat aaacatcagt tggtaaagaa
     3841 agaacattaa aaatggaatc gttgcaccat gaaacatgtt ggggaagctt gtaacatgtc
     3901 tcatcaaaaa gaaatctgcc gggtttccaa taacaccgcc gatatcccgt ccaaaggcca
     3961 atccgaatcc accaaatacc cacataatcg ttgttatccc aacggagaga aaagattgag
     4021 acatgatcgt tagtatatta ttcttccgtg ctaatccgcc gtaaaaaaaa gctagaccag
     4081 gagtcatcag gcaaaccatt gctgtacata aaatcatgaa tgctgtatct cctgtattga
     4141 taggtaatgt attcattttt ttcgcctcct ttctacgatt acgagtataa aagaaggtgt
     4201 agttgttttt ttcttctgtt tttttgaatt aatacttgca tttataaaag acagacaatt
     4261 aataaaagct tgatgtgttg tgctcttttt cgtttttcac acaaataaag acaaaaaata
     4321 aacggtcttc tttttataga aaaccgttta ttttcgtctt tttttatttt taaagatatt
     4381 ttttcataag gaataaagaa tacttcatat aaaatatata aaaaagaacc gcagcgagtg
     4441 tcgctacggt tctcaaattt gt
//
LOCUS       DAFBVQ010000117         4459 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.123, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000117 DAFBVQ010000000
VERSION     DAFBVQ010000117.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4459)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4459)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4459
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.123"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(462..887)
                     /locus_tag="LLC22_002755"
     CDS             complement(462..887)
                     /locus_tag="LLC22_002755"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373688.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435956.1"
                     /translation="MKKLIVLFILSAGLLTLTGCDLFGGSDQSSDETTDSSVLKAEKA
                     DTTNSVYTLKVRKDMDLSAGQLTFTDKKMEWTRTYQTQGTDSSESSEEKTVLTDIKIT
                     TKDDEYIISGKENKKETTVIFTKIGNYRLKDEDGNIYSL"
     gene            1261..2232
                     /locus_tag="LLC22_002756"
     CDS             1261..2232
                     /locus_tag="LLC22_002756"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312122.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LacI family DNA-binding transcriptional
                     regulator"
                     /protein_id="HBK5435957.1"
                     /translation="MASIRDVAKMAGVSVGTVSRYLNGQQLKEKNMKKIAEAISALDY
                     KENIIAKGLKNNRSFSIGLLINGISSRFGSEVVSGIERVAEENGYSLLLSGFADQPEK
                     IEQKIEYLMKHVIDGLIVFLSEEEWSGFEMLTKMSIPVIALNCPEGPAGIDTILVNDR
                     ESVAKVIAHHGEQGHKKIGFIAATQTDYVARERLAGAKEAVQNDPSIQLEVFTGDYSR
                     KSGYYGAKALLEKGATAIFVSNYNMSIGAIECFNQEGVRIGKDIAFSHYDYLDKNDLS
                     ILPKITITPPTDKIGERAAEQLLKRIKKEEEENEKVIVMENIIHGIN"
     gene            2264..3661
                     /locus_tag="LLC22_002757"
     CDS             2264..3661
                     /locus_tag="LLC22_002757"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010738851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5435958.1"
                     /translation="MKKYQFPANFWWGSAASGPQTEGRISGDGKGENIFDYWYKKEPQ
                     KFFDQVGPEKTSQVYTKYQEDVQLMKQTGHNSFRTSIQWSRLIPDESGTINEEAVRFY
                     HRYFDELIENGIEPFVNLYHFDMPMYLQEKGGWLNRETVEAYEKYAKSCFELFGSKVK
                     KWFTHNEPIVPVEAGYLYRWHYPEESDMKKAIQVGYHEALASALAIKSYHEMEQGGVI
                     GIILNLTPSYPRDESNPEDVKAAQIADAFFNRSFLDPAVKGEFPSELIEIVKELDLMP
                     VIHAEDLTVIKENTVDLLGINYYQPRRVKAKETPIDTKNGPMPEDYFDNYEMPGRKMN
                     PYRGWEIYEQGIYDILINVRDHYGNIDCFISENGMGVENEARFIKEDGMIHDDYRIEF
                     VQSHLKYVHQAIQEGANCLGYHMWTCMDNWSWTNAYKNRYGFISVDLAQDGKRTIKKS
                     GHWFKDVSDKNGFEA"
     gene            3820..4443
                     /locus_tag="LLC22_002758"
     CDS             3820..4443
                     /locus_tag="LLC22_002758"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299979.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435959.1"
                     /translation="MRKKRPFLLFWLFGFFLLLILSAAFSGKMTADLAQKETEKIVAS
                     KESVDNFKKEFSTYWWAEYKITANYEKGELDIYLPKGKEENQFINIDDVLSAISLRQY
                     QFKDKHLTVLLLTHDGDKVARLKNGKVITAYSEKVDKKVVADRLAEWKKTNEQVKKTT
                     VSSQKNESTGTSPSDSGSGQTITGSEENQASIITNESSQGQYQSYGQ"
BASE COUNT         1562 a          715 c          909 g         1273 t
ORIGIN      
        1 aaaaattact acgtgatgta gaataagcct ttctatcgtt tggttatttt atattcaaat
       61 atttgaaata aataaatctt tactctttga tttgtaaact gaaatgatcc actgtttgtt
      121 ttactgatga agcttgatca aaggaagaag ctgagtttga agttcataaa aatcagccat
      181 agtgagtttt gcttggattt gtttatcttc ttctactttt tacataattt tgaacaggat
      241 aagattcaaa tgttttaaat gaatctttga ctagtttgtg acagttgtcg catatgctca
      301 agcttccttg gtcattaaat tctgtatgga tatttttgtt gttattacat gtacaataat
      361 caggactatc gatcatccat ttcgtctcct ttacaatcat cttgcttctt tactatagca
      421 gaaaagaagg ggagaaacaa aagaagatcc aacagacggc actatagact gtagatgttg
      481 ccatcctcat ccttcaaacg gtaattaccg atttttgtaa atatgactgt tgtttctttt
      541 ttattttctt ttcctgaaat aatatattcg tcatctttgg tagtgatctt gatatctgtc
      601 agcactgttt tttcttcaga tgattcagaa gaatcagttc cttgtgtctg atacgtgcgt
      661 gtccattcca tttttttatc tgtaaatgtc aactgtcccg cggataaatc catatcttta
      721 cgtactttta gcgtatatac actgttggtg gtatctgctt tttccgcttt taagacagaa
      781 gaatcggttg tttcgtccga ggattggtca gagccgccaa acaaatcaca gccagtcaat
      841 gtcaaaagtc ccgcagacaa aataaatagt acgattaatt tcttcaaaat acttccccca
      901 tttgatagga taaagaaatt ataccattgg aatgtaaaac ttcaaacgga tggaagagaa
      961 aaacgcacaa aacacccaca aatagagtaa attttagaat aaaattttaa aaaggcaaaa
     1021 aatccgccac tttcagaaag cgttttaaaa aagtgttgca atcttttaaa aaaatgctat
     1081 attaaaaatg aaccggttca aatacttgtt taagtataat taatagtgag aggaagttgc
     1141 tctactgaag actttagtta tatggatatt gatgacaagc aacactatgc aaagaatgcg
     1201 gtcatcataa tcgaacaaca agaaagagaa atcaaatgta actggcagga gtgagaatgt
     1261 atggcatcga tccgtgatgt ggctaagatg gctggtgttt cagtgggaac agtttcccgt
     1321 tacttgaatg gtcagcaact gaaggaaaag aacatgaaaa aaatagcaga agcgatttca
     1381 gcgttggact ataaagaaaa catcattgct aaagggttga agaataatcg aagcttctct
     1441 attggacttt tgataaacgg gatttccagc cgttttgggt cggaagttgt ctcagggatc
     1501 gaaagagtag ctgaagaaaa tgggtatagc ttattattaa gcgggtttgc cgatcagcca
     1561 gaaaaaattg aacaaaaaat tgaatacctg atgaagcatg tgatcgatgg gctgattgtc
     1621 ttcttatccg aagaagagtg gtctggattt gaaatgctca caaaaatgag tattccagtt
     1681 atcgcattga attgtccaga aggaccagca ggtattgata caatattagt gaatgatcga
     1741 gaaagtgtag caaaagtgat cgctcatcat ggtgaacaag gacataaaaa aatcggattt
     1801 attgctgcca ctcaaacaga ctacgtagca agagaacgtt tagcaggagc caaagaagcg
     1861 gtccaaaatg atccatcgat ccaattagag gtctttacag gagactattc tagaaaaagc
     1921 ggctattacg gggcaaaagc attattagaa aaaggggcaa ctgctatttt tgtcagcaat
     1981 tacaatatgt cgattggtgc catcgaatgt ttcaatcaag aaggtgtcag aatcgggaag
     2041 gatattgcgt tcagtcacta tgattattta gataaaaacg atctgagtat ccttccgaaa
     2101 atcacgatca cgccaccaac agataaaatc ggggaacgag cagcagaaca gctgttaaaa
     2161 cgaatcaaaa aagaagagga agaaaatgaa aaagtgattg tgatggaaaa tatcatacat
     2221 ggaatcaact aaaacgaact aaaaaagaaa aagaggtgct ttgatgaaaa aatatcaatt
     2281 tccagcaaat ttttggtggg gttctgcagc aagtggccca caaacagaag gaaggatttc
     2341 aggcgatgga aaaggagaga acatttttga ttattggtac aaaaaagaac cgcaaaagtt
     2401 ctttgatcaa gtaggacctg aaaaaacctc gcaagtttat acgaagtatc aagaggatgt
     2461 acagttgatg aaacagactg ggcataattc atttcgaaca tctatccaat ggagccgttt
     2521 gatacctgat gaatctggaa caatcaacga agaagccgtt cgtttctatc atcgttattt
     2581 tgatgagttg attgaaaacg gtatcgaacc ctttgtgaat ctgtatcatt tcgatatgcc
     2641 gatgtatctg caagaaaaag gcggatggtt gaaccgagaa acggttgaag cctatgaaaa
     2701 atatgccaaa agttgttttg aattgtttgg ttcgaaagta aaaaaatggt ttactcataa
     2761 tgaaccaatc gttccagtcg aagcaggtta tttatatcga tggcattatc cagaagagtc
     2821 agatatgaaa aaagcgatcc aagttggcta tcatgaagcg ttggcttcag cgttagccat
     2881 caaatcttac catgaaatgg agcaaggtgg tgttattggt atcatcttga atctgacacc
     2941 aagctatcca agagacgaat caaaccctga agatgttaaa gcagcgcaaa tagcagatgc
     3001 gttcttcaat cgttcattcc ttgatccagc tgtaaaaggc gagtttccaa gtgaattgat
     3061 tgagatagta aaagaacttg atctcatgcc tgtgatccat gcagaggatt tgacggttat
     3121 caaagaaaat acagtagatc ttttaggtat caattattac cagccacgcc gggtaaaagc
     3181 aaaagaaaca ccaatcgata ctaaaaacgg tccaatgcct gaggattatt tcgacaatta
     3241 tgaaatgcct ggtcgtaaaa tgaatcctta tcgcggatgg gagatctatg aacaaggaat
     3301 ctatgatatt ttgatcaatg tacgagatca ttatggaaat atcgactgct ttatttctga
     3361 aaacggtatg ggtgtagaaa acgaagcacg atttatcaaa gaagatggca tgatccacga
     3421 tgattatcgg atcgaatttg tccaatctca tctgaaatat gtccatcaag ccattcaaga
     3481 aggtgccaat tgtttaggct atcatatgtg gacatgtatg gataactggt cgtggaccaa
     3541 tgcatataag aatcgatatg gctttatttc agtagactta gcacaagatg gaaaaagaac
     3601 aatcaaaaaa tcgggtcatt ggttcaaaga cgtatcagat aaaaacggat ttgaggctta
     3661 agaaagaata gttgagagca aatgcgtgaa attctccatt cttaccattt tgtgaaaaag
     3721 aagttcaatt atttacgatc tttttcaact tttttgtctt tctatttcat tttttgtata
     3781 taatagaata gtcaaaatta aataggagtg gaggaaagca tgaggaaaaa aagaccgttt
     3841 cttctctttt ggttattcgg ttttttctta ctgcttattt tatccgcagc attttcagga
     3901 aaaatgacag cagatcttgc tcagaaagaa acagaaaaaa tcgtagcaag caaagaatca
     3961 gtagataatt tcaaaaaaga attctcaact tattggtggg cggagtataa aataactgcc
     4021 aattacgaaa aaggcgaatt ggacatttat ttgccaaaag gaaaagaaga aaatcaattt
     4081 attaatatcg atgacgtact tagtgcgatt tctctcagac aatatcaatt taaagacaag
     4141 catttgaccg ttttgctttt gactcatgat ggcgacaaag tagcccgttt gaaaaatgga
     4201 aaagtgatca ccgcttattc tgaaaaagta gacaaaaaag tggtcgccga tcgtttagcg
     4261 gaatggaaaa agacaaatga acaagtcaag aaaacaactg tctcttctca aaaaaacgag
     4321 tcgacaggaa caagtccttc agattctggc agtggacaaa cgataacggg aagtgaagaa
     4381 aatcaagcct caattattac gaatgagtca tcacaaggac aatatcaatc ctatggacaa
     4441 tgaaaaacag aggttgtga
//
LOCUS       DAFBVQ010000118         4430 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.124, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000118 DAFBVQ010000000
VERSION     DAFBVQ010000118.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4430)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4430)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4430
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.124"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(543..2048)
                     /locus_tag="LLC22_002759"
     CDS             complement(543..2048)
                     /locus_tag="LLC22_002759"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326472.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5435960.1"
                     /translation="MIKPKKSEKRELKGPSLTIKWAFASSFFIFVVFTIFAVITYKSS
                     INLIVAKERNNVERTISEVASRLANSDEELTLVNTYRNLTKATNDGDEVVDHTSLVEG
                     NLMKIDSFIAELGQPSMDLYVYDLDENLIFKTHENSRNLIQTTRKVPTIVTLEGKTGF
                     LSIQPIYSKGTREKIGYAQSFYELSSFYDIRNKLLLTLIVLEVVSLILSSILGFFLSS
                     YFLKPLKVLRDTMDTIRKDPQSDIHMPEIDTNDELADLAEIFNEMLDRMRLYIEQQEQ
                     FVEDVSHELRTPVAIIEGHLSLLNRWGKDDPEILEESLSASMQEISRMKSLVQEMLDL
                     SRAEQVDVHYANETTKGKEVTYQVYNNFKILYPDYVITLDDDLTKEVTLQIYRNHFEQ
                     LIIIILDNAVKYSTTRKEVHISISSTLNEFEIAIQDFGEGIPKEDLNKIFNRFYRVDK
                     ARARTKGGNGLGLSIAKQLVENYKGRILAESVVGQGTIFRIFIPIAKAEDK"
     gene            complement(2045..2731)
                     /locus_tag="LLC22_002760"
     CDS             complement(2045..2731)
                     /locus_tag="LLC22_002760"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010763438.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5435961.1"
                     /translation="MSNILIIEDEKNLARFVELELKHEGYNAEVHYNGRTGLDAALNN
                     EWDAILLDLMLPELNGLEVCRRVRQVKNTPIIMMTARDSVIDRVSGLDHGADDYIVKP
                     FAIEELLARLRALLRRIDIEGDKNVAKQTTITYRDLTIEKENRVVRRGNEVIELTKRE
                     YELLLTLMENVNVVLARDVLLNKVWGYETEVETNVVDVYIRYLRNKIDVPGEESYIQT
                     VRGTGYVMRS"
     gene            complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LLC22_002761"
     CDS             complement(2924..4345)
                     /gene="gndA"
                     /locus_tag="LLC22_002761"
                     /EC_number="1.1.1.44"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342997.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="NADP-dependent phosphogluconate dehydrogenase"
                     /protein_id="HBK5435962.1"
                     /translation="MSKQQIGVVGMAVMGKNLALNIESRGYSVALFNRTGAKTTAVVE
                     EHPDKNFKATYTIEEFVESIEKPRRILLMVKAGPATDATIQELLPHLDKGDILIDGGN
                     TFFKDTMRRNEELANSGINFIGTGVSGGEEGALKGPSIMPGGQKEAYALVAPILEQIS
                     AKAEDGAPCVTYIGPNGAGHYVKMVHNGIEYGDMQLIAESYDLMKNILNLSVEEMADI
                     FKEWNQGELDSYLIEITADILTRKDDEGTGKPVVDVILDAAGNKGTGKWTSQSALDLG
                     VPLPLITESVFARYISAYKEERVQASKILSRTNDFEFTGDKKELVEKIREALYFSKIM
                     SYAQGFAQLRVASKEFDWDLPFGEIAKIWRAGCIIRARFLQKITDAYDKNPEIENLLL
                     DDYFVEITKKYQQSVRDVVALAVQAGVPVPTFSSAIAYFDSYRAERLPANIIQAQRDY
                     FGAHTYERVDKEGIFHYSWYHEE"
BASE COUNT         1238 a          919 c          729 g         1544 t
ORIGIN      
        1 tctttttgtt ttaacaactc tttaatctta tcagattcag aagagaatgt caacaacttc
       61 tttgtttatt ttttctaaac gtctttgcca ctcattagca gcgacttgat tatcatacca
      121 tctttattgt tatttgtcaa taactttttc gaagtttttt tcgataaaat caagctttat
      181 tagctatctc atccaaacga cttcgttatt ataacatgac atcaaaagtg cgtcaacact
      241 attttttata atttttagtg acaccttaaa ggaatcattt agaacaaata ataatatagc
      301 aatctcttta taaaattgca atagaaaatt ccctattttt atttattatt tttaaacacg
      361 aatattacag cattttattg ttttttcgtt catctaaaag atacttacat ttaattaacg
      421 gatgttattc tatttaattg ttcgctagtt tttttataat gacatccctg aatttctcac
      481 ttgcttgtat tttgtacctt attctttgtt ggatatataa aaaaacaagt aaagcacatg
      541 ctttacttgt cttctgcctt tgcgatagga ataaagattc taaaaattgt cccttgccct
      601 actacacttt ctgctaagat acgtccttta tagttttcaa ccagttgttt agcgatagac
      661 aaccccagac catttccacc cttcgttcta gctcttgctt tatccactcg ataaaaacga
      721 ttgaagatct tattaaggtc ttctttgggt attccttcgc caaagtcctg aatcgcgatc
      781 tcaaattcat tcagagtgga agaaatagag atatggactt cttttcgtgt agttgaatac
      841 tttactgcgt tatccaatat gataatgatt aattgttcaa agtgattacg ataaatttgc
      901 agggtcactt cttttgtcaa atcatcatct aaagtgatca catagtctgg atataatatc
      961 ttgaaattat tataaacttg ataggtgact tcttttcctt tagttgtttc attcgcataa
     1021 tgaacatcta cttgttctgc tcttgataag tctagcatct cttgaactaa gcttttcata
     1081 cggctgattt cttgcatgct ggcgcttaat gattcttcta atatctcagg atcatctttc
     1141 ccccaacgat ttagcagact aagatgccct tcaataattg caacaggtgt ccttaactca
     1201 tgagatacgt cttccacgaa ttgctcttgt tgttcaatat acaaacgcat acggtcaagc
     1261 atctcattga atatttcagc taaatctgcc aattcatcat ttgtgtcgat ttcaggcatg
     1321 tggatatctg attgcggatc tttacgtata gtatccattg tatctctgag taccttgagt
     1381 ggttttaaga aataagaaga taaaaagaaa cctaaaatac tacttaagat caaagaaaca
     1441 acttctaaaa caataagagt caataatagc ttatttcgaa tatcatagaa agaagataat
     1501 tcatagaagc tttgcgcata gccgatcttt tctcttgtac ctttagaata tataggctgg
     1561 atagataaaa agccagtttt tccttctagt gtaacgatcg ttggaacttt acgtgtagtc
     1621 tgaatcaggt ttcgactgtt ttcatgggtt ttaaaaatca agttctcgtc caaatcataa
     1681 acataaagat ccattgatgg ctgccctagc tcagctataa aggaatcgat cttcattaag
     1741 tttccttcga ccagtgaagt atgatctacg acctcatctc cgtcatttgt cgctttcgtc
     1801 agattacgat acgtatttac taatgtcagt tcttcatccg agttagccaa acgagaagct
     1861 acttctgaaa tcgtacgctc tacattgttt ctttcttttg ccacaatcag attgatagat
     1921 gatttatagg taatgacagc gaaaattgta aacacaacga atatgaagaa agaactcgca
     1981 aaggcccact tgattgtcaa ggagggccct ttcagttctc ttttttccga ttttttcggc
     2041 tttatcacga gcgcatcaca taacctgttc cgcgtacagt ttggatatag ctttcctccc
     2101 cgggaacgtc aattttgttg cgaagataac gaatatatac gtccactacg tttgtttcaa
     2161 cttctgtttc gtatccccac actttattta gtaaaacgtc acgtgctaat accacgttca
     2221 cgttttccat taaagtaagc agcaactcgt attctctttt tgttagttca attacttcat
     2281 ttccgcgacg tacgacacgg ttttcttttt cgatagtcaa atcgcgataa gtaatagtag
     2341 tttgtttagc cacattttta tcgccttcaa tatcgattcg acgcaacaat gcacgaagac
     2401 gtgctaataa ttcttcgata gcaaatggtt tgacgatgta gtcatctgct ccgtggtcaa
     2461 gtccagatac acgatcgatc acagaatctc ttgcagtcat cataatgatt ggtgtatttt
     2521 tgacttggcg tacacgtctg cagacttcta aaccgttcaa ttctgggagc atcagatcca
     2581 acaatatggc atcccactca ttatttaatg ccgcatctaa accagttcgg ccgttgtagt
     2641 ggacttctgc gttataccct tcatgcttca actctagctc gacaaatcgt gccaagttct
     2701 tttcatcttc aatgattaga atattgctca tttattattt tatcctttct attctactgg
     2761 ctttttaaaa actctatcat tataccgata atatgcttaa aaatctatag tcattttatc
     2821 atggatagca attttaaaaa agagctgaag tctactcata acaatcgact tcagctcttt
     2881 cgtcctcttt ttattttctc atttcctaac agccgaaaga ctattattct tcatggtacc
     2941 atgagtaatg gaagattcct tctttgtcga cacgctcata ggtatgtgcg ccaaagtaat
     3001 cgcgttgggc ttggattata tttgcaggca gacgttctgc tctgtatgaa tcgaagtaag
     3061 cgatggctga tgagaaagtc ggtacaggta cgccagcttg gacagccaag gcaacgacgt
     3121 ctctgactga ttgctgatat tttttcgtga tttcaacgaa gtaatcatct agcaataaat
     3181 tttcgatctc aggatttttg tcataggcat ccgtaatttt ttgcaagaat cgagctcgga
     3241 tgatacatcc agcgcgccag atttttgcga tttcaccaaa tggcaagtcc caatcaaatt
     3301 cttttgaagc gacacgtaat tgagcaaatc cttgggcata actcatgatt ttactgaaat
     3361 acaacgcttc tcggattttt tcgaccaatt cttttttgtc tcccgtgaac tcaaaatcgt
     3421 tcgtacgaga caaaatcttg cttgcttgta cgcgttcttc tttataagca gaaatatagc
     3481 gggcaaatac agattcagtg atcaatggaa gtggcacacc taagtcaagc gcgctttggc
     3541 ttgtccattt acctgttcct ttattcccag ctgcatcaag gatcacatct actactggtt
     3601 tacctgttcc ttcatcgtct ttacgtgtca gaatgtcagc agtgatttct atcaaatagc
     3661 tgtctaattc gccttgattc cattctttaa agatatcagc catttcttct actgaaaggt
     3721 ttaaaatatt cttcattaag tcataagatt cagcaatcag ttgcatatct ccatactcaa
     3781 taccgttgtg taccattttc acataatgtc cggctccatt tgggccaata tatgtgacac
     3841 atggtgctcc gtcttctgct tttgcagaaa tttgctctaa gattggtgca actagcgcat
     3901 aggcttcttt ttgtccacca ggcatgattg aaggtccttt taaagctcct tcttcaccac
     3961 cggaaacgcc tgtaccgata aagttgatgc cagagttggc taactcttca ttacgacgca
     4021 tcgtatcttt aaagaatgta tttcctccgt caatcaaaat atcgccttta tcaaggtgag
     4081 gaagtaactc ttggattgtt gcatctgttg ccggtcctgc tttgaccatt agcaagatcc
     4141 gacgtggttt ctcgatagat tctacaaatt cttcgattgt atatgttgct ttgaaatttt
     4201 tatctgggtg ttcttctact acagcggttg ttttagcccc tgtacgattg aataaagcca
     4261 ctgaatagcc gcggctttct atgttcaagg ctagattttt acccataacg gccataccga
     4321 caacgccgat ttgttgtttt gacatatgaa ctcctcctac atacgggatt tctccctaat
     4381 ctcttacatt atagcttaac acggctacat tgcaaactaa agaacaacat
//
LOCUS       DAFBVQ010000119         4401 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.125, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000119 DAFBVQ010000000
VERSION     DAFBVQ010000119.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4401)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4401)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4401
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.125"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(99..1619)
                     /locus_tag="LLC22_002762"
     CDS             complement(99..1619)
                     /locus_tag="LLC22_002762"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBK5435963.1"
                     /translation="MTKMESELLVQIKQLTQLLEIQQQENTLLREQIAEMNRRLFGRK
                     KETPPVDGQIDLLDDSTFNEPEHTGQESQEPITVSSFKRRKRKGLKALSLEGLPEVPI
                     HYELKGADCLCEDCGHTLHDIGATRLREEPLYVPAHIEKQVIYQHAYHCRECEALGET
                     KIKKAPVPKPLINNSLGSSSIVTQSIWEKFVKKVPAYRQEKEWHALGFPLDRKKITNW
                     HIKVSEMVLEPIYNCLHQELSNQEVLHADETSYRVLNTHKEKTFYWLYASGKSEEKQV
                     VLYEHANSRSVDEPKSFLESFSGFLHTDGYAAYGKLPVNNVYCWAHVRRKFFEALGKQ
                     PSPKSHAKIGLDFCDKMFRIERTFNKLSAEERFVARKETLQPVMTEFFHWCESFAYLP
                     KSQLGKAVQYAVNHKDGLQIVLLDGRLELSNNRAERAIKELVIGRKNWLFSKSLKGAR
                     SNGIILSIIQTAVANGLNIRKYLNHLFTEIPNLSSMTPEALRAYLPWNQQIQEICK"
     gene            complement(1862..2047)
                     /locus_tag="LLC22_002763"
     CDS             complement(1862..2047)
                     /locus_tag="LLC22_002763"
                     /inference="COORDINATES: protein motif:HMM:NF017528.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence hypothetical
                     protein"
                     /protein_id="HBK5435964.1"
                     /translation="MPMLIDATALKHIFIVCGKTDLRKGIDGLAAFVIEEYDLDVYDQ
                     ALFLFCGTKKDRFKALY"
     gene            complement(2031..2213)
                     /locus_tag="LLC22_002764"
     CDS             complement(2031..2213)
                     /locus_tag="LLC22_002764"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300846.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435965.1"
                     /translation="MNKKDIVPVQFSSAAQKSQIDTKPKLACRIKSEDKEIFIYNGMD
                     KYLLYTLLKELNANAH"
     gene            2454..2672
                     /locus_tag="LLC22_002765"
                     /pseudo
     CDS             2454..2672
                     /locus_tag="LLC22_002765"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
     gene            3167..3766
                     /locus_tag="LLC22_002766"
     CDS             3167..3766
                     /locus_tag="LLC22_002766"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016622858.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5435966.1"
                     /translation="MKTVEPIRDKKKIDAMKAILASGKYGQRNLVLFSIGINTAYRIS
                     DLRQLKLADVLEISRGRVVVKDRLAMKEQKTAKHNSVYISNKLRKTILEYVQQEFPDQ
                     LLQQDFDGYLFPSRKGTNEPLNRQSLWRIIHDAGTAIGLKDIGPHSMRKTFGYFLYKQ
                     GTKTEIIQSLLNHSSQRETLRYIGITQEDKDTAVKSLDL"
     gene            3830..>4401
                     /locus_tag="LLC22_002767"
     CDS             3830..>4401
                     /locus_tag="LLC22_002767"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002356097.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bacteriophage abortive infection AbiH family
                     protein"
                     /protein_id="HBK5435967.1"
                     /translation="MSTLYIIGNGFDLSHGLKTRYTDFSKWVEKSHSEIFDKIDTMIN
                     ENNEVRSTADDKIGWFNFESSLHELIQSPVFEDYVEESKDYLIGYGHEDWSDSAHHDF
                     QNMVYDYVVSLEELQQLFKEWIRKEIQPTIEHKIPKYQFSSDVLFFTFNYTDVLEILY
                     KQPKENIYHIHGSYDDIIIGHSENFDNFIG"
BASE COUNT         1403 a          799 c          785 g         1414 t
ORIGIN      
        1 ataattcagt agttttgagc gtaagcgtgt catagaatgg tacctaaaca caaatagccc
       61 gatttgatac actcaaatca ggttatttgt ggcttatatt atttacagat ttcttgtatc
      121 tgctgattcc atggcaaata agcgcgtagc gcttcaggtg tcatcgaaga cagattggga
      181 atctctgtaa aaagatgatt taaatatttg cggatgttta acccattcgc aacagctgtc
      241 tggataatac tcaatataat tccatttgat ctagcgcctt ttaagctttt agaaaatagc
      301 cagttttttc gaccgatcac taactctttg atggcacgct ctgctcggtt atttgaaagt
      361 tccaagcgtc catcaagcaa cacaatctga agtccgtctt tatgattgac tgcgtattga
      421 accgcctttc caagctgcga ttttggcaaa taagcaaaac tctcacacca atgaaaaaat
      481 tcagtcatca caggctgcaa cgtttccttc ctcgctacaa acctttcttc tgcgctaagc
      541 ttattaaagg tccgttcgat tcgaaacatc ttgtcacaga agtctaatcc tattttggca
      601 tgactttttg gggacggttg tttacccaat gcttcaaaaa actttctgcg aacatgcgcc
      661 caacaataaa cattgtttac cggcagcttt ccataggccg cgtaaccatc agtatgcaag
      721 aaaccgctaa atgattctaa aaaacttttt ggctcatcaa cggaacgcga atttgcgtgc
      781 tcgtagagca caacttgttt ttcttcgctt ttacctgaag catataacca gtaaaaggtc
      841 ttttctttat gagtattcaa tacccgatag cttgtctcat ccgcgtgtaa gacctcctga
      901 ttgcttaatt cttgatgaag gcaattgtag attggctcta aaaccatttc acttaccttg
      961 atatgccaat tagtgatttt tttacgatca agagggaaac caagtgcatg ccattctttt
     1021 tcttgtcgat atgccggcac ctttttaaca aatttttccc aaatactctg tgtcacaatt
     1081 gaagaggaac ctagactatt attgatcaac ggtttaggaa caggcgcttt tttgattttt
     1141 gtttctccta atgcttcaca ttctctgcaa tgataggcat gttggtagat gacttgtttt
     1201 tctatatggg caggaacata caatggctct tctctaagcc ttgtcgcacc gatatcatgt
     1261 aaagtatgac cacagtcttc acacaaacaa tcggcacctt ttaattcata atgaatagga
     1321 acttcaggca gaccttctaa tgaaagtgct ttgagtccct tgcgttttct gcgtttaaaa
     1381 gaagataccg taatgggttc ctggctttct tgtccagtgt gctctggttc attaaaagtt
     1441 gagtcgtcta ataaatcgat ttgcccatct acgggtggtg tttctttttt tcgtccaaac
     1501 aagcgtcgat tcatttcagc aatttgttct ctaagaagag tattttcctg ttgctggatt
     1561 tcaagcaact gtgttaattg cttgatttgt acaagaagtt cagattccat ttttgtcatt
     1621 tttacaccac cattctagcg attttcttac atctattata ccattttatg acaacgaaaa
     1681 acagacaaaa tccttgattt aacaaggttt tcgtctaata tatcgcacct tttttcgttt
     1741 cttttagcgt acatttttct tcgattgaaa ggccagtcag taagacttct tttctggaac
     1801 gcggccattg aaggtaccca ctttcaaatc ttttgtacat taatacaaat ccattttgat
     1861 cctagtaaag agccttgaag cgatctttct tcgtaccgca aaataagaaa agcgcttgat
     1921 cgtaaacatc aaggtcatat tcttctataa cgaaagctgc tagtccatca attccttttc
     1981 gaagatctgt ttttccacaa acgataaaaa tatgtttcaa tgcagttgca tcaatgagca
     2041 ttggcattca actcttttaa caaggtatac aaaagatatt tatccattcc attataaata
     2101 aatatttcct tatcttccga tttgattctg caagctagtt ttggcttggt gtcaatttgc
     2161 gatttttgag ccgcacttga aaattgaact ggtacaatat cttttttatt cattcgtttt
     2221 tctccttcta tatttgatag tttaattata gaagaaagat aatcggcgta cgagatacta
     2281 tcctatgaca cgcttacatt taatttaata ttttgcctca aattagccac actttttata
     2341 gaactaagag gaaaaatgaa gttttcttcc tattaatata gttgtttgaa atcttaaata
     2401 tagcgtttta cgatgtaatg ggaagtatgg tgaataaatc aactatgttc gtacgaagca
     2461 tttactcaac taatttaatc gaatctttca ataaacaaat caagaaatac agccaccgca
     2521 aggaacagtt ccaaaatgaa gagtcgatgg aacgtttctt agtctcgtct tttgatactt
     2581 acaaccaaaa attcctaggt cgcagtcata aaggtttcca acaggccgaa ggcgagctcg
     2641 aacaaatgct gagtcaaccg atggagaatt agaaacaatc tacagtaggg aagaaccatt
     2701 gacacaaaat tattgacgct cccaactaaa agtgtcaaaa taatgatgaa atcatttagt
     2761 tcttataaat tagaaaagag aaaataaata ttccatatct actttattgg atccgtaaca
     2821 tgactaaatt ctgaatactt tttaaagctt atcatttggt aaaactgaat ataagttaat
     2881 tatatagact gaaaattttg aattttcaga atagaataac ttaaaagtac tgacaaaatt
     2941 ttttaaaggg gcaatattaa tgttctgaga taatcaaatc ctaccgaaaa tatcaaaaat
     3001 ccaatgtgac acaatcagat tgtgtctcat tcgagggaat cacacaatcc cacgtggctc
     3061 taggcagaat tgaatttttg cttggggctt tttccttata ttgattttga atgagactta
     3121 ttatatgtta taatgcaatt aagtatcatt ggagagggcg aagaaaatga agacggtaga
     3181 acctattcga gacaaaaaaa agatcgatgc gatgaaggca atcttggctt cgggaaaata
     3241 tggccaacga aatttggttc ttttttcgat tgggatcaac accgcctatc gcatttctga
     3301 tttgcgtcaa ttgaagctgg ccgacgtgct ggaaatttca cgcggtcgcg tggtggtcaa
     3361 agatcgatta gcgatgaagg aacaaaaaac agctaaacat aattcggtct atatttccaa
     3421 caaattgcga aaaacgattt tggagtacgt tcaacaggaa tttcctgatc aactccttca
     3481 gcaagatttt gacggttatt tgttccctag tcgaaaaggg acgaatgaac cgctcaaccg
     3541 ccaaagtctg tggcgaatca ttcatgatgc tggcacggca atcggattga aagacattgg
     3601 cccacattcc atgcgaaaaa cgttcggtta ctttctctat aaacagggga ccaaaacaga
     3661 aatcattcag tccttgttga accattcttc tcagcgcgaa acattgcggt atattggtat
     3721 tacacaagaa gacaaagata cagctgtaaa aagcttagat ttataatata aaagttaagt
     3781 ttaaacatgg atagttttaa attagtagat tgagtgttgg gaggaaagaa tgagtacatt
     3841 atatattata ggaaacggtt ttgatttaag tcatggttta aaaactagat acactgattt
     3901 ttcaaaatgg gttgaaaaaa gtcatagtga aatattcgat aaaatagaca caatgataaa
     3961 tgaaaataat gaggtgagaa gtacagctga tgataagata ggttggttta attttgaaag
     4021 tagtttgcat gagttaattc aaagtccagt ctttgaagat tatgtagaag agtctaagga
     4081 ttatctcata ggttatggac atgaagattg gtcagattct gcccatcatg attttcaaaa
     4141 tatggtttat gattatgttg tttctctaga agaattacaa caacttttca aggaatggat
     4201 acgcaaagaa atacagccga caatagaaca taaaattcca aaataccaat tttcgtccga
     4261 tgtactattc tttacattca attatacaga tgttttggaa attctataca agcaaccgaa
     4321 agaaaacata tatcatattc atggcagtta tgacgatata ataatcggcc actccgagaa
     4381 ttttgacaac tttataggag a
//
LOCUS       DAFBVQ010000120         4317 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.126, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000120 DAFBVQ010000000
VERSION     DAFBVQ010000120.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4317)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4317)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4317
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.126"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            148..1137
                     /locus_tag="LLC22_002768"
     CDS             148..1137
                     /locus_tag="LLC22_002768"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349057.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="protein rep"
                     /protein_id="HBK5435968.1"
                     /translation="MKKKKQDLINGTFREKKKNLKKVVAFSDNRISPKMRELMTGCGS
                     YLEFIATIDKEKKKLVQAHFCKNRFCPLCAWRKARKDSMMLSIMMQAIAEEKQYQFIF
                     MTLTTPNVKAECLNDEIDLFNHALKKMFMRKRVKTSIKGYVRKLEITYNKKRNDYNPH
                     FHLILAVNKSYFTDKDYYIKQSEWLDLWREVTGKTGINPDGTDEITQLDIRKVKGFQQ
                     EKAVQEVAKYSAKDFELTESQEVFDTFYHAMKGRQLITFNGVFKEYKKKYESGDLDRY
                     KKKDENEYFWFLTASWMRKESKYAVDYREMSADERNYFSGMYVDEKSVEGENE"
     gene            1134..1553
                     /locus_tag="LLC22_002769"
     CDS             1134..1553
                     /locus_tag="LLC22_002769"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351943.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435969.1"
                     /translation="MTDSTDKMTIKALADELGITKNTVRNYLVKAGYDLARYKKNGII
                     LLDKELIGVARSIYRSKGGQLTGHLPVNSTGSDFPLEKENEFLRDQLAEKDKHISELT
                     EMIRDQQKLTLLQQQKNDQLLLENQELKNRKWWQFWK"
     gene            1532..1870
                     /locus_tag="LLC22_002770"
     CDS             1532..1870
                     /locus_tag="LLC22_002770"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435970.1"
                     /translation="MVAILEVRCDMDKIDLREETVNRIEVMYERLADYLNLSDEDNYS
                     EMLERMMDVLNSVINADLAKSSVLTNEFVHKHLAQTTDEAEKEFWLKLMSHIMQLNQI
                     SVINSKEKGM"
     gene            1874..2236
                     /locus_tag="LLC22_002771"
     CDS             1874..2236
                     /locus_tag="LLC22_002771"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435971.1"
                     /translation="MGMTLADIKVQEEKLKKEQAKLRQQKKRLIEKENAAMGKALRKR
                     FGFESFADFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNEYDGLLGVIPSKK
                     SQMNESKFMSIFNDVNLR"
     gene            2458..3865
                     /locus_tag="LLC22_002772"
                     /pseudo
     CDS             2458..3865
                     /locus_tag="LLC22_002772"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
BASE COUNT         1506 a          605 c          988 g         1218 t
ORIGIN      
        1 aaaaaaaaag attgcttttt cttccctagt attttatagt tttaattgac tagaaaaaaa
       61 ctaaactaga aaggagagca atctattttt tgttatcggc ttttcagcct tttttgtata
      121 caaaatttgt agattcagta tagcaagatg aaaaagaaaa agcaagattt gattaacgga
      181 acatttcgag aaaaaaagaa aaatttgaaa aaagtggtgg catttagtga taatcgaatt
      241 tctcccaaaa tgcgtgaatt gatgacaggc tgtggttcat atttagaatt tattgcaacg
      301 attgataagg agaaaaagaa attggtccaa gctcactttt gtaaaaatcg tttctgtccg
      361 ttatgtgctt ggcgtaaagc tcgtaaggat tcgatgatgt tgtcgattat gatgcaagct
      421 attgcggaag aaaagcagta tcaatttatt tttatgacgt tgacgacacc gaatgtaaaa
      481 gcggaatgtt tgaacgatga aattgatttg tttaatcatg cattgaaaaa gatgtttatg
      541 cgcaaacggg ttaagacttc gattaaaggc tatgtgcgaa aattggaaat cacgtacaac
      601 aaaaaacgga atgactataa cccgcatttt cacttgattt tggcagtaaa taaatcttat
      661 ttcacggata aagattatta tatcaagcaa tcggaatggt tagatttgtg gcgggaagtg
      721 accggaaaaa cgggaattaa tccggatggt accgacgaaa ttacccagtt ggatattcgc
      781 aaggtcaaag ggttccaaca agaaaaagca gtacaggaag ttgcgaaata ttcggcaaaa
      841 gattttgaac tgaccgaaag tcaggaagtg tttgacacat tctatcatgc aatgaaaggt
      901 cgtcagttga ttacgtttaa cggtgtattc aaagaataca agaaaaaata tgagtcgggt
      961 gaccttgatc gttataagaa aaaagatgag aatgaatatt tttggttttt gactgcttcg
     1021 tggatgagga aagaatcgaa atatgcggtt gattatcgtg agatgagtgc tgatgaaaga
     1081 aattattttt caggaatgta tgtcgatgaa aaatctgttg agggggaaaa tgaatgactg
     1141 attcaacgga taaaatgaca attaaggcgc ttgctgatga actaggaata accaaaaata
     1201 cagtgagaaa ttatctagtc aaagccggat atgatcttgc tcggtacaag aaaaatggaa
     1261 ttatcttgct agacaaagag ttgattggtg ttgctcggtc aatttatcgg tcaaaaggtg
     1321 gtcaattgac tggtcattta ccggtcaata gcacgggcag tgattttcct ttggaaaaag
     1381 agaatgagtt tttgcgtgat caattagctg agaaggacaa acatatttct gaattaacag
     1441 aaatgattcg tgatcaacaa aaattgaccc tgcttcagca acaaaaaaac gatcagttgt
     1501 tactagaaaa tcaagaatta aaaaatcgaa aatggtggca attctggaag tgagatgtga
     1561 catggataaa attgatttga gagaagaaac agtcaataga attgaagtga tgtatgaacg
     1621 gttagctgat tatttgaatc tttcggatga agataattat agtgagatgc ttgaacgaat
     1681 gatggatgtt ctcaactcgg ttatcaatgc tgatctagca aaatcttcag ttttgactaa
     1741 tgaatttgtt cataagcatt tagcgcaaac aactgatgaa gctgaaaaag aattttggtt
     1801 gaaattaatg agtcatatta tgcagttaaa ccaaatttcc gttattaatt ccaaagaaaa
     1861 ggggatgtag tttatgggaa tgactttagc agatattaaa gtgcaagaag aaaaattaaa
     1921 aaaagaacag gcgaaacttc gccaacagaa gaaacgattg attgagaaag aaaatgctgc
     1981 aatgggcaag gctcttcgca agcgttttgg gtttgaatct tttgctgatt ttgagcggtg
     2041 gttatcgtca atttctgacg atcagcaaca cgaaaaatca gtggataatg agtggcttgc
     2101 tgatgaaaaa tcagcgccaa gcgaacgaga ttatcccaat gaatatgacg gcttactcgg
     2161 agtgataccg agtaaaaaaa gtcagatgaa tgagagtaaa tttatgtcaa tttttaatga
     2221 cgtgaattta cgataagcta ttattttgcg tgaagcaaaa taaagcgtaa aaggagttga
     2281 gagcgtgaca cgctttcggc tccttttttc gttgtcactt gtgacagcga aatccctcgg
     2341 agagcgtttg gaattgtgac agtcatgtca caattaggaa aacgttactc tttgacaaag
     2401 agtaacagaa aggtttacac tctttttatt agcgacagcg cgaaggaggg gtctaacttg
     2461 gggtttagta tttcgttcaa aaagggaaca aagaatacaa gcatttctca taataatcgt
     2521 gagttaactg atagccaaaa aatcaatgac tggcataagc atattgattt cacaaaatcg
     2581 gatgaaaata tctatttgga acaaacaaat attcgtgaaa aatatgaaga attattcggt
     2641 gaagccgtag aaaaatataa tgcaaagcag aaaagagccg atagaaaaat cgaggactat
     2701 ttagcaaagg ttcgcaagga taaaaaaatt ggaaccacag cgagaattta tcgtgcaaat
     2761 tggtactctt gatgattttc gtactactcg tgatgatggt tcttctactg gcatatcgga
     2821 acaacaagca gaacaaaatc gagtgattgc caacaaaatt ttagttgagt atttcaaaga
     2881 atttaaagaa cggaatccta gtttatccgt ctacaatgct gttattcata atgacgaagt
     2941 aagtccgcac ctgcatttga atattgttcc tgttgctgaa gggtataaac ggggtgttca
     3001 aaagcaacca agttttaaca aagccttgca acagcagggt ttacgagcag ataaagagaa
     3061 tggtcgagtg atttggaata attttaggaa tcaggaagtt gagtcaattg aacgtttgat
     3121 ggcagatttt ggttgggagc gtgagttagt cggtactaac aaaatcaaag atgttcacga
     3181 atataaagaa atcatgagcg agatttcaga attgcgtcaa acggccgtaa aagagcgtga
     3241 gagcgtttct gatgagttgg ggtatatttc taggcaaaga gaagaaaacg agcgagaaaa
     3301 ggctctggtg gcttctgaga gagcaaagat tgaagaagag aagaaaaata tgctgaatgt
     3361 aaaaaaagag atggcggtca ttttccaaaa agatattgtt cctttagaaa gtttcaagag
     3421 gcttcctgat ggttcgtatc atttatctgg gaatgatttt gttgatttgt atcaacgagc
     3481 tacgagagca acaaatgcca agagaaatgc tgataacatg agtgagcaat atttacagat
     3541 gcttgagcaa aatacagaat taaatgagta tgtagctaca ttggaagaag agcgtcattt
     3601 gtctggtaga aaacaattag cagatttaca agtggaaaat aaaaagctga aagaagaaaa
     3661 tcgctcttta cgccagcgtt tagagcgatt aaaaaaagca tttcaaaaat cgatcactcg
     3721 tttgtctatc cgttttggtc ttgcagaaaa ggatatgggg ctttctgagg aattagaagt
     3781 attagagcag gagaaaacct tattttatcg tcaaaacgtc tcacagcata aattagagcg
     3841 ttctgaagat gagatcgagt ggtagttacg atgtgcagtc aacggtaccg gaggcggtct
     3901 gtgccgagga taaggagttg acggctaaac cactagccta ttaagctgac atttgctaaa
     3961 aaatggcaag tccatttttt ggccaaccta gcgttagcga aagtttgggg gcgccctttt
     4021 caaagggagc ggttttattt ttgcatgact aagaatgagt gggaaaaact taaccgcatt
     4081 tctaacaggc ggttaaagta tcaaagtttg acccttccct taaaaatgca gtggtcaatt
     4141 gaccgaattt tatgcagaag tgggtttttg agttttgggg tttgaaacga gaaaaaagag
     4201 gtcgatttcg acctcttttt ttgatgtttc ttcttatctt gatactatag gcaactattt
     4261 ctgcgaagaa atcggggcta tagtatgggt ctatcccttg tggctctaag gaagaac
//
LOCUS       DAFBVQ010000121         4157 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.127, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000121 DAFBVQ010000000
VERSION     DAFBVQ010000121.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4157)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4157)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4157
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.127"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            179..775
                     /locus_tag="LLC22_002773"
     CDS             179..775
                     /locus_tag="LLC22_002773"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010737813.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK5435972.1"
                     /translation="MNIAASRKLINFISIIGLGLSIALTIYFINLGVFKDLNALRGLV
                     GDSIILGPIIFVFIQILQVVIPIIPGGISTAAGVLIFGPYAGFIYNYIGICIGSIIIF
                     LLGRRYGKPFILSMISDKTYNKYIGWLDNQNRFEKLFALAIFLPVAPDDALCLMAGLT
                     NMSVKRYTLIILIAKPLSIFLYSMALIYGGQYLSGLLG"
     gene            899..2698
                     /locus_tag="LLC22_002774"
     CDS             899..2698
                     /locus_tag="LLC22_002774"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326703.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerophosphodiester phosphodiesterase"
                     /protein_id="HBK5435973.1"
                     /translation="MNYLKRSLGNAWDFLKGTQAYFRDVLLMHGFILFICLPLLSSTT
                     RFILHRGAIDYLSYDNIPSIFSQHPGVLLSLIVVLMTILLLVYFEFTFLLMSVFFIKK
                     KEPISLKQLLHLTILQLKKVRPITFLFFLAYFLLILPISGLSFNSDLLSKIKIPAFIM
                     DFIFANRWIIVSSFLLVYIFLGYIGIRLIFALPEMILRDRPFRAAIRESWSLTKSRLL
                     AITGQFIVIGGTILLLSSLGYIVVILAQSMVEQFFPDYALISAVFAMTLLQGILLFNI
                     VMSTVGIFYIIVDFMDDEGFLPEIPKWFIPQAPNLRFSALKNTGLTLFAVFFGIGVCL
                     YNMDYLTSAVQTKPVTVSHRGVSTQNGAQNTLEALEKTSRDYHPDYVEMDVQETKDGH
                     FVVMHDANLRHLTGVNGTPQDLTLKELTNLTVTENGVQAPVCSFDSYLEKAHKLNQKL
                     LIEIKTSKKDSDDLVERFVHKYRKVILENHHILQSLTYQTVSDLKEAEPNFYVGYILP
                     FNIVGPPVTPADFLTMEYSTINRNFINSAHQDGKEVYVWTINDSDAMSRMMFYGVDGI
                     ITDEMGLLNESVKQTDEEITYSDKLLNFVLGVG"
     gene            complement(2976..3188)
                     /locus_tag="LLC22_002775"
     CDS             complement(2976..3188)
                     /locus_tag="LLC22_002775"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002308849.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435974.1"
                     /translation="MVKAEVGRSYICKPIGVSHELIGCIERTYINTAVVYVESYDQRD
                     YQLINESKYRMLVKFCDISAPAELVS"
     gene            3650..3799
                     /locus_tag="LLC22_002776"
     CDS             3650..3799
                     /locus_tag="LLC22_002776"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293931.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435975.1"
                     /translation="MTFTKTNMQYRVAFDTTSNRFMAIDAQNENNVAFGITIEQAVRA
                     LNESR"
     gene            complement(4052..>4157)
                     /locus_tag="LLC22_002777"
     CDS             complement(4052..>4157)
                     /locus_tag="LLC22_002777"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5435976.1"
                     /translation="ASKRNNIPRKSLDYRTPLEVFLSYVSIDDLSNLI"
BASE COUNT         1228 a          707 c          729 g         1493 t
ORIGIN      
        1 tttaaaaaaa acaagttatt aaataagtct ttagttggat gtttttttga gatcaatctt
       61 ttatacttat gatgaactta caaaattgtt tgttttctgt catatcaaaa aatggcgcag
      121 ttagttgctt ttctagtaaa gtatagttaa caaagaacct ctaaggagtt gatgaataat
      181 gaatattgct gcctctcgaa aactgataaa tttcatatcc attatcggat taggcctatc
      241 aatcgcgctg acgatttatt ttattaattt aggtgttttc aaagatttga atgcgttaag
      301 aggattagta ggtgattcca tcattttagg accgattatt tttgtcttca tccaaatcct
      361 gcaagtagtt attccaatca ttcctggagg gatcagtact gcagctggtg tcctgatatt
      421 tggcccttat gctggattta tctataacta tattggaatc tgcattggtt cgattatcat
      481 ttttctgcta gggcgtcgtt atggaaagcc attcatactt tccatgatta gcgataagac
      541 atataacaaa tatattggct ggctggataa tcaaaaccgt tttgagaagc tgtttgctct
      601 agctattttt cttccagttg ctcctgacga tgcgttatgt ttgatggctg gattgacaaa
      661 catgtcagtg aaacgatata cactaatcat tttgattgct aaaccactgt cgattttctt
      721 atatagtatg gccttgattt atggaggtca atatctaagt ggtcttcttg gataatattt
      781 attttgtaaa attagtcatt gattgacaat gttaaatctg ggaaagggtc tgcaaaacac
      841 actgcaccct ttcctttttc attagatttg cgctacaatg tgaagagcag gtgataggat
      901 gaattatttg aaacgtagct taggtaatgc ttgggacttt ttaaaaggaa cacaagctta
      961 tttccgtgat gtcttgctga tgcatggctt tattttattt atttgtttac ccttattgag
     1021 cagtacgacc cgttttattt tacaccgagg ggcaattgac tatttgtctt atgacaatat
     1081 tccttcaatt ttttctcaac atcctggggt tctactctcg ttaatcgtag ttttgatgac
     1141 gattttactg ttagtttatt tcgaatttac ttttcttttg atgagtgttt tttttattaa
     1201 aaagaaagaa ccaatctctt tgaagcaact cttacacttg acgatacttc agctgaagaa
     1261 agtgagaccc attacttttt tgtttttcct tgcttatttt ttattgattc taccgatcag
     1321 cggattaagt tttaattctg atctactgtc aaaaataaaa atccccgctt tcattatgga
     1381 ttttattttt gctaatcgtt ggatcatcgt cagttccttt ttactcgttt atattttcct
     1441 tggctatatt gggattcgac tgatttttgc tttaccggaa atgattctac gggatcgtcc
     1501 ttttcgagca gccattcggg aaagctggtc attgaccaaa tcgcgtcttt tggccatcac
     1561 gggccaattt attgtgattg gcggtacgat tttactcctt tcttctttag gatatatcgt
     1621 tgttattttg gcacaaagta tggttgaaca atttttccca gactatgcat tgatcagcgc
     1681 tgtgtttgct atgacgcttt tacaagggat tttattattc aatatcgtga tgtctaccgt
     1741 agggattttt tatatcattg ttgatttcat ggatgacgaa ggcttcttgc ctgagatccc
     1801 taagtggttt atcccacaag cccccaactt gcgtttctct gcgctgaaaa acactggttt
     1861 gactcttttt gcagtttttt tcggtattgg cgtctgtctt tacaatatgg attatctgac
     1921 ttcagctgtt cagacaaaac cagtgactgt ctctcacaga ggtgtgagta cccaaaatgg
     1981 ggcgcaaaat actttagaag cacttgaaaa aacaagcaga gactatcatc ctgattatgt
     2041 agagatggat gttcaggaaa caaaagatgg tcatttcgta gtgatgcatg atgcaaatct
     2101 tcgtcactta acaggggtaa atggaacacc acaggatctt acattgaaag aattgacaaa
     2161 tcttacagtt actgaaaacg gagtgcaagc ccctgtttgt tcttttgatt cttatttgga
     2221 aaaagcacat aagctaaacc aaaaattact tattgagatc aagacctcta aaaaagattc
     2281 ggatgacctt gtcgaacgat ttgtccataa ataccgcaaa gttatcttag agaaccatca
     2341 tattttgcaa agtttgacgt accaaaccgt ttcagattta aaagaagcag aaccaaactt
     2401 ttatgtgggc tacatcttac ctttcaatat tgttgggccc cctgtgacgc ctgctgattt
     2461 tctgacaatg gaatatagta cgatcaaccg taacttcatt aattctgccc accaagacgg
     2521 aaaagaagta tatgtatgga caatcaacga ttcagatgct atgagtcgca tgatgtttta
     2581 tggtgtggat ggtatcataa ccgatgagat gggactacta aatgaaagtg tgaaacaaac
     2641 agatgaagaa atcacttatt cagataaact gctaaatttt gttttgggag tcggctaatc
     2701 aaaaatcgtt aatgaaaaaa gtctttatac aacaaaaaac gcataacctg ccaccgcagg
     2761 tatatgcgtt ttttgtttga cgctcataat gtgtgcttaa ctttctcttg attccttcat
     2821 cgcacgaaca atagctaaaa tagcaggaat tgcagagatc actgcaagaa taattcccat
     2881 tttccctgaa ctttttcttt ttggcatatc ttctcgctcc cttctgtctt tatttatatt
     2941 ataagggagt tcttgcgaat tctcaaaaat actgtttaag aaaccaattc agcaggtgcg
     3001 ctaatatcac agaattttac gagcatgcga tacttgcttt cattgataag ttgatagtct
     3061 cgttggtcat aactttcaac atacacgaca gccgtgttga tatatgtacg ttcaatacag
     3121 ccgattagtt catgagatac tccgatcggt ttgcatatat aagatcttcc tacttctgct
     3181 tttaccattt cattccctct tttctttatt tttattttgt tttttcttta ttttataata
     3241 acaaattacc ttgtatttga aaacgttttt atccattttt ttatttttta ttttgagtat
     3301 ctttctgctt tttagataac tattttttaa cacgatctta gacgttgtga caaaaacgtt
     3361 tgtttatatt cctatgttgt tcgtgcgttt ttttctttat attgctaagt tatttataaa
     3421 gaggtgagca tatgatttat attcaagcaa tagtatttgt aaccttgatg attgggctac
     3481 ttatcggatt aaaagaaaat agctaaacca tttaagaaaa aataaataag gaaaatgata
     3541 aatgcttttt aattgcatca aaaaacgtac gatgctaaac ttggtataag ttcgaaagtt
     3601 taaaggaaac tttcaagaac taaattacat tacaaaggag atgaatttta tgacgtttac
     3661 aaaaacaaat atgcaatacc gcgtagcttt tgatacaact tctaaccgtt ttatggcgat
     3721 tgatgcacaa aacgaaaata acgttgcgtt tggtattaca atcgaacaag cagtccgagc
     3781 attaaacgaa tctagataag gagtgaacca ttccaaatgg cgactgatga gatctcggaa
     3841 aatcaataaa agacgtttgt aacggtaatc cgcgacaaac gtctttttgt attcattaca
     3901 tatatttgga aattgtctct ctttatctct agacctaaac aaaaacacaa gttctaatat
     3961 caaccatctc gttttttatg acaattttgt tagctgtttc gatgataata ttccgttatt
     4021 atctgtataa tatttaatat aatcttaatt gtcaaattaa gttagacaga tcatcaatac
     4081 ttacgtaact caaaaatact tccaaaggtg ttcgataatc cagtgatttt ctaggaatat
     4141 tatttcgttt agatgcg
//
LOCUS       DAFBVQ010000122         4129 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.128, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000122 DAFBVQ010000000
VERSION     DAFBVQ010000122.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4129)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4129)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4129
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.128"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..734)
                     /locus_tag="LLC22_002778"
     CDS             complement(<1..734)
                     /locus_tag="LLC22_002778"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HBK5435977.1"
                     /translation="MMDYSKEPVNDYFLIDMKSFYASVECIERNLDPLTTELVVMSRA
                     DNTGSGLILASSPEAKKRYGITNVSRPRDLPQPFPKTLHVVPPRMNLYIKRNMQVNNI
                     FRRYVADEDLLIYSIDESILKVTRSLNLFTTEGTRSQRRKKLAQMIQENIKEELGLIA
                     TVGVGDNPLLAKLALDNEAKHNEGFVAEWTYENVPEKVWNIPEMTDFWGIGSRMKKRL
                     NQMGIMSIRDLANWNPYTIKNRLGVIG"
     gene            1184..1798
                     /locus_tag="LLC22_002779"
     CDS             1184..1798
                     /locus_tag="LLC22_002779"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001261742.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5435978.1"
                     /translation="MRVAYIRVSSIDQNEQRQIEEMKKFGAERIFIEKQSGATITHRP
                     VFQEALDYVRDQDIFIVEAIDRLGRNYDEIIASVNYLKKKNVKLIITSLPIMAEAIGN
                     PLLDKFIKDLIIQILAMIAEQERTESKRRQAQGIKIAKANGVYKGRPKLYSADAKDPQ
                     RRLVYKSIVEDLKNGVAIAKIAKDYNVTRQTVYRIKKDSMVNDK"
     gene            complement(1963..2787)
                     /locus_tag="LLC22_002780"
     CDS             complement(1963..2787)
                     /locus_tag="LLC22_002780"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001809248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435979.1"
                     /translation="MIERLKDFMISVWDVAMLADESNYTSSIYRLEDSNWIEISLELK
                     TLPNSVNYIIRDITSEAQQLVNYMHGHESIPFSLILLKRSKNISNTRDRFISIITACE
                     IGVKEFYQQEKPDLTLIFENLQSPPVDKLLGSMFKGYFNIEFPKEIRKEIKNFIEKRN
                     KLVHSPQGSKPTIEECFECYMAVLKTFNFFYKINDSFMYRDFYEESIELTPTEPNKSQ
                     ITLSKELERKVESQELAIGISITNVSTYKELYEAKSQDNKDFVENIDKEPTNTVGD"
     gene            complement(3425..3682)
                     /locus_tag="LLC22_002781"
     CDS             complement(3425..3682)
                     /locus_tag="LLC22_002781"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632526.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Txe/YoeB family addiction module toxin"
                     /protein_id="HBK5435980.1"
                     /translation="MIKAWSDDAWDDYLYWHEQGNKSNIKKINKLIKDIDRSPFAGLG
                     KPEPLKHDLSGKWSRRITDEHRLIYRVENETIFIYSAKDHY"
     gene            complement(3675..3944)
                     /locus_tag="LLC22_002782"
     CDS             complement(3675..3944)
                     /locus_tag="LLC22_002782"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016632525.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system Phd/YefM family
                     antitoxin"
                     /protein_id="HBK5435981.1"
                     /translation="MEAVAYSNFRQNLRSYMKQVNEDAETLIVTSKDVEDTVVVLSKR
                     DYDSMQETLRTLSNNYVMEKIRRGDEQFSKGAFKTHDLIEVESDD"
BASE COUNT         1337 a          743 c          566 g         1483 t
ORIGIN      
        1 ccaatcacac ctagtctatt cttaatcgta taaggattcc agttagcaag atctctaatg
       61 ctcataatcc ccatctgatt gagtcttttt ttcattcgag agccaattcc ccaaaagtcc
      121 gtcatttcag gaatattcca tactttttca ggaacgtttt cgtacgtcca ttccgcaaca
      181 aatccttcat tatgctttgc ttcgttgtct aaggctagtt tagccaaaag gggattatct
      241 ccgacaccta ctgtagcaat caatcctagc tcttctttaa tattctcctg gatcatttga
      301 gccagcttct ttctccgttg acttcgtgtt ccttcagtcg taaaaagatt cagtgatcgg
      361 gtcactttta agattgattc atcgatcgag taaatcagta gatcttcatc agccacatat
      421 cttctgaaaa tattatttac ctgcatattt cgcttgatat ataggttcat acgtggtgga
      481 acaacgtgta gtgttttagg aaatggttgt ggtaagtcac gtggtctact cacatttgta
      541 ataccatacc gcttttttgc ttcaggagaa gaagctaata tcaatcctga accagtatta
      601 tcagctcgac tcataacaac aagttctgtt gttaatggat ctaaatttct ttctatacat
      661 tcgacacttg cgtaaaagct tttcatatcg attaaaaagt aatcatttac tggctctttt
      721 gaataatcca tcataaataa cactccattc tttcacatta tacaaacata tgttcgatat
      781 tgtaaagaag aaatagctaa atacataaaa aaagaagcat aggtatgcta tcaccctgct
      841 tcttcttttg atttgtatga tcaatttatt ctatcacttt actaattaat ttgaaaatct
      901 aataaaaact ctcactctaa aagagtgaga gactgcaaat tagagtacgg acttttttgg
      961 agttccgttc tttaatatta acaaatgaat aaaatcctta caacatttga gaataagtta
     1021 tcagtagaca cttacaaaaa attctcatac tatttcctcc atcattagtt tttgtctata
     1081 taaggtttac cctaaataga cactggtata acattgaaaa atatggcttc ctcgtgtatg
     1141 attagggtgt attttaaata gttgcagaaa gtaggtaaaa gttttgagag ttgcatacat
     1201 acgtgtctca tcgatcgatc aaaatgaaca acgccagatt gaagaaatga aaaaattcgg
     1261 tgcagagaga attttcatcg agaaacaatc tggcgcaacg attactcatc gacctgtttt
     1321 ccaagaagca ttagattacg tccgagatca agatattttt attgtggaag ctattgatcg
     1381 acttggaaga aattatgacg agatcatcgc ttcagtcaat tacttgaaga agaaaaatgt
     1441 gaagctgatc attactagtt taccgatcat ggctgaagca attggcaatc ctctcctgga
     1501 taaattcatt aaggatctga tcatccaaat tttggccatg atcgctgaac aagaacggac
     1561 tgaatcgaaa cgtcgccagg cacaaggaat taagatcgca aaagcaaacg gcgtctacaa
     1621 agggcggccc aaattataca gtgcagacgc aaaagatccc caacgtcgcc ttgtttacaa
     1681 aagcatcgtt gaagatctta aaaatggtgt tgcgattgct aagattgcta aagactacaa
     1741 tgttacgaga caaaccgtgt atagaataaa aaaagacagc atggtcaatg acaaatagtt
     1801 gatcatgctg cttttattat cttctcatct ttaatttcct acatataatt actatctata
     1861 aaattaagtc ttactcagaa cagataaagc ataaaattcc aacaaaccat tttttactta
     1921 actaaataaa gagtctgtta atataatctt cacttattta cgttaatccc ctactgtatt
     1981 tgttggttcc ttatctatat tttctacaaa atccttatta tcttgtgatt tagcttcgta
     2041 taattctttg tatgtcgaca cattggttat actaattcct atagctagtt cttgagactc
     2101 tacttttctc tctagctcct ttgacaaagt gatttgagat ttatttggtt ccgttggagt
     2161 caattctata gattcttcat aaaaatctct atacataaag ctatcattaa ttttataaaa
     2221 aaaattaaat gtttttagca ctgccatata acattcaaaa cattcttcta tagttggttt
     2281 acttccttga ggagaatgaa ccaatttatt acgtttttct atgaaatttt taatttcctt
     2341 tcttatttct ttcggaaact caatattaaa gtacccttta aacatgctcc ctaataattt
     2401 gtctacaggg ggagattgta aattctcaaa tattagagtt aaatcaggtt tctcttgttg
     2461 ataaaattcc tttaccccta tttcacaggc tgtaattatc gaaataaacc tatctctagt
     2521 atttgatata tttttacttc ttttaaggag tataagagaa aaggggatac tttcgtgtcc
     2581 atgcatgtaa ttaactaatt gttgagcttc agaagttata tctctaatta tatagttaac
     2641 ggaattagga agtgtcttta actctaatga aatttctatc caattactat cttctaatct
     2701 gtatatgctc gaagtataat ttgattcgtc agcaagcatc gctacatccc aaacactgat
     2761 cataaaatct tttaaacgtt caatcatttc agcaatattg ctaaaatcag ctaatttttc
     2821 tttagaataa aaaaaaacat ttatatcaga atcaataaat tctatttttt tattactata
     2881 tcgtcatcat tatcttgacc atttatgttt attgttccct gagtggggag tacttctttc
     2941 aaattcaagt taaatttata ttccattact tctcctccaa tatataaaaa ttacttaact
     3001 gtatccaaat ttaatatgta aataaatcat taatttttag ctaaattcta tgagaagttt
     3061 atttttgttg tttttgctaa ttaactaaaa ctagtacaaa aaatttaaaa tagattatta
     3121 aacctattgc ttattctatt cagtcatata tataagcgtc atcctttagt aactaacatc
     3181 ccacactaca atagtattat aacatatcta ttcaacttca aattgttgaa atttaagcca
     3241 tttatattta cttttcctca actttagaaa tgattttact aaccttatat ccgtaatacg
     3301 cgtaacaaac acattcatta ataacaatca acactaagct atattagctt tttaaatgac
     3361 tagggtaaat aaaataagga tcaaaaactt ttaagtttct gaccctttcc ttacttccga
     3421 ttggttaata gtgatctttt gcagaataaa taaatatcgt ttcattttca actctatata
     3481 tcagtctatg ttcatctgta attcttctgg accattttcc agataaatca tgctttaatg
     3541 gctcaggttt tcctaatcca gcaaaggggg aacgatcgat atcttttatt aacttgttaa
     3601 tcttttttat attgcttttg tttccttgct catgccaata aagataatca tcccaagcat
     3661 catcagacca agccttaatc atcagattca acctcgatta agtcatgtgt tttaaatgca
     3721 cctttggaga attgttcatc tcctcgacga attttttcca tgacgtaatt attagaaagt
     3781 gttctcaacg tttcttgcat agaatcataa tctctttttg ataatacaac aactgtatct
     3841 tctacatctt tacttgttac aataagtgtt tcagcatcct cattaacttg tttcatataa
     3901 ctacgtaaat tttggcggaa atttgaataa gctactgctt ccattccttt caccccttat
     3961 ttatttctat aaaacaattg tacattatat tgtacaatta agcaaatgat taatattcta
     4021 acttcttata attaaaagtg ctatcacttt tagtttttag gataaaaagt gacgtcactt
     4081 tttgagtgct ggtacctcaa atcctgcttt ttcttgggca atcaataaa
//
LOCUS       DAFBVQ010000123         4112 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.129, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000123 DAFBVQ010000000
VERSION     DAFBVQ010000123.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4112)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4112)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4112
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.129"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(39..281)
                     /locus_tag="LLC22_002783"
     CDS             complement(39..281)
                     /locus_tag="LLC22_002783"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723801.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GlsB/YeaQ/YmgE family stress response membrane
                     protein"
                     /protein_id="HBK5435982.1"
                     /translation="MGFIWALIVGGIIGAIAGAITNKGSSMGIIANIIAGLVGSAIGQ
                     ALLGTWGPTIAGMAIIPSLIGAIILVLVVSFFARKL"
     gene            complement(313..870)
                     /locus_tag="LLC22_002784"
     CDS             complement(313..870)
                     /locus_tag="LLC22_002784"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295944.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Asp23/Gls24 family envelope stress response
                     protein"
                     /protein_id="HBK5435983.1"
                     /translation="MENKNMNTTNGSVLANEKGENRMMNGELTYEDKVIQKIIGYALK
                     DVDGLLTLDGGFFSNMAEKLVNTDNVTAGINTEVGKKQVAVDLDVIVEYGKDIEDIYN
                     QIKELISTEVNNMTHLDVIEVNVNVADIKTQEEYQKDQETVQDKVTEAAKSTGQFASR
                     QTDKAKSAVGKGAQKVKENNEPRVQ"
     gene            complement(883..1071)
                     /locus_tag="LLC22_002785"
     CDS             complement(883..1071)
                     /locus_tag="LLC22_002785"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005875246.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2273 domain-containing protein"
                     /protein_id="HBK5435984.1"
                     /translation="MKELFSAYKLPIIFGGLGLLLAVLWLTIGFFKTLLIIIMTAIGA
                     GIGFYLKQSGIVDQFFKS"
     gene            complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="LLC22_002786"
     CDS             complement(1084..1650)
                     /gene="amaP"
                     /locus_tag="LLC22_002786"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="alkaline shock response membrane anchor protein
                     AmaP"
                     /protein_id="HBK5435985.1"
                     /translation="MNKGLKIIGVIMSLLLLSVFLAIALINAPYIMPEQLERFRFFTL
                     TNYYMQQYIFWAAVVFAVLAIIILLVVLFYPKSRGTFVMKREDGKLTIDKKAIEGLVR
                     SHLHEEEFIHSPKVRIRSTKNRIHIHVNGDLKRTSSLVGKTGVLMQDIEEEVTKVLGT
                     KETVKVAVTYSGYEEQEDTRDYKHSRVE"
     gene            2067..2240
                     /locus_tag="LLC22_002787"
     CDS             2067..2240
                     /locus_tag="LLC22_002787"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435986.1"
                     /translation="MMKRLYYSLIITIGYLIVSNLGNMVFGISKEFSWTTTLWESLFF
                     FIFVFLLQNYRKK"
     gene            2880..3353
                     /locus_tag="LLC22_002788"
     CDS             2880..3353
                     /locus_tag="LLC22_002788"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339235.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2975 domain-containing protein"
                     /protein_id="HBK5435987.1"
                     /translation="MKFKTLLLKFVVLGISAVFILFGVLFYTQIATSEKGFNFDWQTT
                     LFVSVIYFALLLGIVIAYFLLKLLKKIEDNQAFSTQSLNILKKIERTILFIGFAFFGL
                     LPKFMKVADLDDAPGLMLVGIAVVFIPFAVYTLTSVLEKLLEHAILLKTDHDLTV"
     gene            3362..3589
                     /locus_tag="LLC22_002789"
     CDS             3362..3589
                     /locus_tag="LLC22_002789"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008266675.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix transcriptional regulator"
                     /protein_id="HBK5435988.1"
                     /translation="MAIIVNLDVVLAQKKMSVTELSEKVGITMANISILKNGKAKAIR
                     FSTLEKICQVLECQPGDLLTYKNDSNTIPEE"
BASE COUNT         1234 a          740 c          618 g         1520 t
ORIGIN      
        1 ttgttcttca tttcaacata agtttttctt caatttgctt ataatttacg tgcaaagaat
       61 gaaacgacta atactaaaat gattgcaccg atcaatgatg gaatgatagc cattcctgca
      121 attgttggtc cccaagttcc tagtaaagct tgtccaattg ctgaacctac taaaccagca
      181 atgatgtttg cgatgatccc cattgatgat cctttattcg tgattgctcc tgcaattgct
      241 ccaatgatac cgccgacgat taatgcccaa ataaatccca ttttaaattc ctcctaactg
      301 acttcttact tcttattgta cacgtggttc gttattttct ttgacttttt gtgcaccttt
      361 gcctacagca gattttgctt tatctgtttg gcgtgaagca aattgtcctg tggattttgc
      421 tgcttctgtt actttgtctt gtactgtttc ttgatctttt tggtattctt cttgtgtttt
      481 gatgtctgca acattcacat tcacttcgat aacatctaaa tgtgtcatat tgtttacttc
      541 agtactgatc aattctttga tttggttgta aatatcttcg atgtctttac cgtattctac
      601 gatcacatct agatccacag ctacttgttt cttacctact tctgtattga tacctgctgt
      661 tacgttatct gtgttgacta atttttcagc catatttgag aaaaatccgc catctaatgt
      721 caatagacca tctacatctt tcaatgcata accgatgatt ttttggatga ctttgtcttc
      781 ataagtcaat tcaccattca tcatgcggtt ttctcctttt tcatttgcca aaactgatcc
      841 atttgttgta ttcatgtttt tgttttccat ctttgtttcc tcctatgatt taaaaaattg
      901 atcaactatt cctgactgtt tcaaataaaa accgattcct gcgccaattg ctgtcatgat
      961 tatgatcaac aatgtcttga aaaatccaat cgttaaccat aaaacagcta gcagtagtcc
     1021 aagaccccca aagataatag ggagcttgta tgctgaaaat agttctttca ttatttggcc
     1081 ctcctattcc actcgagagt gcttgtagtc tcttgtatct tcttgttctt cataaccgct
     1141 gtatgtgact gccactttga ccgtttcttt tgttccgagt actttagtta cttcttcttc
     1201 gatatcttgc atcaatacac ctgttttccc tactaatgaa gaagttcgtt tcaagtctcc
     1261 gttgacatgg atatggattc gatttttcgt tgaacgtatc cgtactttag gtgaatgaat
     1321 gaactcttct tcgtgtaaat gggaacgtac caacccttcg atcgcttttt tgtcgattgt
     1381 tagtttgcca tcttcccgtt tcataacgaa agttcctctt gactttggat agaaaagaac
     1441 gactagcaag atgataatag caagaacggc aaatactaca gctgcccaga aaatatattg
     1501 ttgcatgtag taattcgtta aagtaaagaa gcgaaatcgt tccaattgtt caggcataat
     1561 atacggcgca ttgatcaacg caatcgctag aaatactgaa agtagcagta aactcatgat
     1621 aacaccgatt atttttaacc ccttattcat tttccacctc ctataaactt atttttaccc
     1681 tgtaaataac tctaccgaca atcacagtat agatagcgaa cagttagcat agcatcagta
     1741 aataaagcgc taccaaacat tgctggatca taacggcgtt ttattgccag tctgatactg
     1801 aaataacaat tgcttactta ttctctattt acttttgatt gctggctata cttaaaggat
     1861 attattcaag attaaaaatt gcaaagatta tgctcagtta ttattacaag attctattta
     1921 tttattaaat tttttcggag aattaaaaaa tacaataaat aactttagtt actttaatgc
     1981 gttcttactt tatttttata ttatcatttt tcttattcac ttctttggtt tatactattc
     2041 ttataaataa aaacgaggta tgtcctatga tgaaaagatt gtactattca ttgatcataa
     2101 cgattggcta tttgattgta tcaaatctag gaaatatggt atttggtatc agtaaagaat
     2161 tcagttggac tactacatta tgggaatctc tattcttttt catcttcgta tttttgttac
     2221 aaaattatcg aaaaaaataa acatgtgcca tctatctgtt ggcacatgtt ttaggattta
     2281 tggtactttt tattcggcaa tccattttat ttttctactt cttcttaata cctctaacac
     2341 ttttgattta taaactaatc caatgcatct acttgcgctt attaagctat ttcagctaga
     2401 tagtaccacc ccatgcgtca atgcttgatt ttccttttgt ataacattgt ataagcaata
     2461 aaggacaaat aagtggtgat tacaccaaac cattgaataa gaaaaattct gatacgtaaa
     2521 taaacatgaa cttgaaaaaa ttaatgaatc ggttagctac tacgtagttg tcttttttct
     2581 catacagttc tgttaactta cacttctctt cgctagataa taaaaaatcc tccaactgta
     2641 ttgtccaata taatcccagg catctaaact agcattatag aagagacaca catagaatct
     2701 aaaataactg gttttaaatg tttcttacaa tcaaaaaaag ctgttaaatg cactccacac
     2761 cttcatactc tatcattttt tataaacgat atatttttat tggttttcga taaaaaatag
     2821 ttgttttaca ataattattc tgctatattt tagctatcaa agataaaaga gggataaaaa
     2881 tgaaatttaa aacattgcta ttaaaatttg tcgttttagg tataagtgcc gtatttattt
     2941 tgttcggcgt acttttttat actcagatcg ctacaagcga aaaaggattc aattttgatt
     3001 ggcagaccac attatttgtt tctgtcattt actttgccct tctcctaggg atcgttattg
     3061 cttatttctt attgaaacta ttgaaaaaaa tcgaagataa ccaagctttt tccactcaaa
     3121 gcttaaacat actaaaaaaa atcgaacgaa ccattttgtt tattggtttc gccttttttg
     3181 gcttacttcc taaatttatg aaagtagcgg atttagacga tgctccaggt ttgatgttgg
     3241 taggaatcgc tgtcgtattc attccttttg cagtatacac attaacaagc gtgctggaaa
     3301 aactgcttga acatgcgatt ttacttaaga cagatcatga tttgacagtg tgaggtgcga
     3361 catggcaatt atcgttaatt tagatgtagt attagctcaa aaaaaaatga gtgtgactga
     3421 attgagtgag aaagtgggca ttacgatggc aaacatctct attctaaaaa atggaaaagc
     3481 aaaagccatc cgtttttcca ctctcgaaaa aatctgccaa gttttggagt gtcaaccagg
     3541 tgatttgttg acctataaaa atgactcgaa tactatacca gaagaataaa ataaagtaga
     3601 acaaacagta aataaaaaat aatctgaatg atagatgtgt gagactttta gaagttattt
     3661 acgtctatta ttcagatttt ttatttcgat tgaataccgt tttatctata aataagatat
     3721 gtactgactc atacaaaggg ggccttttct tctccatgta ctatcacttt tcctgataca
     3781 actggtttcc tgttacgttg tagttggatc tgcttttagt ataatacttt attcattcca
     3841 ccagactgat agcagtttga gcagtctaaa taatcatgta gtattacagg ccattctgtt
     3901 tcataccttg aagtgcttaa aacttcagct aatggcccat tgtgttaact cttactccat
     3961 tcttttttag taagctccca tatatactgt aaagccttct atatattatg tcatgttgct
     4021 ttttaacatt tactatgtag ttttgataaa atgatttgaa taacagtgat ggacaattct
     4081 tttttatttt taacattatt ttgataataa tg
//
LOCUS       DAFBVQ010000124         4076 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.130, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000124 DAFBVQ010000000
VERSION     DAFBVQ010000124.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4076)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4076)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4076
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.130"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(77..1051)
                     /locus_tag="LLC22_002790"
     CDS             complement(77..1051)
                     /locus_tag="LLC22_002790"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303407.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBK5435989.1"
                     /translation="MSKKGTIINEWEKLTAPSNRRLSVPFMDTPLKIQWSIDRITIVG
                     NLKENIYYHTTHDVLILDFEQLMRLNEGNGYLRSVSNNGWQLLDQHEENIAYIEILKW
                     QEGKGRIDFNPNKISQFLASSMKNFIHDLFIEPHFSRADIACDIIDVPDEFITQYRVV
                     DPVSFKPIYGRNGKLETAYWGSRSSERQIRMYNKKLEQEKKRKIVPKEIVSWWRLELQ
                     LRRGKATDWHAMVYESLDSFASPHYLPADTSVADKMMITALTTEHDYWGQINRKTKYK
                     YRNLLKQESQNDELTNHLRETFAESADDLKKELDTWLLGLDVTEEEEK"
     gene            complement(1500..2917)
                     /locus_tag="LLC22_002791"
                     /pseudo
     CDS             complement(1500..2917)
                     /locus_tag="LLC22_002791"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173818.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="plasmid recombination protein"
     gene            complement(3139..3501)
                     /locus_tag="LLC22_002792"
     CDS             complement(3139..3501)
                     /locus_tag="LLC22_002792"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173819.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435990.1"
                     /translation="MGMTLADIKAQEEKLKKEQAKLRQQKKRLIEKENAEMGKALRKH
                     FGFESFDDFERWLSSISDDQQHEKSVDNEWLADEKSAPSERDYPNESDGLLGVIPSKK
                     SQMSESKFTSMFNDVSLR"
     gene            complement(3505..3852)
                     /locus_tag="LLC22_002793"
     CDS             complement(3505..3852)
                     /locus_tag="LLC22_002793"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321903.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435991.1"
                     /translation="MVAVLEMRCNMDKIDLREETVDRIELMYERLADYLNLPDEDNYS
                     EMLERMMDVLNSTINVGLANSSLITDKFVYGKIAETEDESEKEFWLNILTYVMQLNQI
                     GVIYRNKSKGKEL"
     gene            complement(3923..4063)
                     /locus_tag="LLC22_002794"
     CDS             complement(3923..4063)
                     /locus_tag="LLC22_002794"
                     /inference="COORDINATES: ab initio
                     prediction:GeneMarkS-2+"
                     /note="Derived by automated computational analysis using
                     gene prediction method: GeneMarkS-2+."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435992.1"
                     /translation="MSGKLLDVTQYELILKNNKIDSPIIIPKHAVKYIYAVAESSGEA
                     ND"
BASE COUNT         1154 a          896 c          576 g         1450 t
ORIGIN      
        1 aaaaaaacaa ccacaacgta atcacctgtt aaatttacca accaattttt cttaccaaaa
       61 tacttttgtt tttctgtcat ttttcttcct cctctgttac gtctagccct agaagccatg
      121 tgtctaattc tttttttaaa tcgtctgccg attctgcaaa ggtttctcgt aaatgattcg
      181 tcaattcatc attttgactt tcttgcttca gcaaatttcg atatttatat tttgtctttc
      241 gattaatttg cccccaataa tcatgttctg ttgttaaagc agtaatcatc attttgtcag
      301 ctacacttgt atcagcaggc aagtaatgag gactagcaaa actatctaag ctttcataaa
      361 ccatagcatg ccaatcagtc gctttccctc gtcttaattg taattctaac cgccaccaac
      421 tcacgatttc ttttggcaca atttttcttt tcttctcttg ttccagtttt ttattataca
      481 tccgaatttg acgttcagaa gagcgagatc cccaatatgc cgtctctaat tttccattcc
      541 gtccataaat aggcttaaaa gaaactggat caactacccg atattgtgta ataaactcat
      601 caggtacatc gataatgtcg caagcaatat ctgcacgtga aaagtgaggt tcgataaaca
      661 aatcatgaat aaaatttttc atggaactag ctaagaattg actaatctta ttcggattga
      721 agtctatacg ccctttcccc tcttgccatt ttaaaatttc aatataagca atattctctt
      781 catgttggtc taacaactgc caaccattat tactaacaga tcttaaataa ccgttacctt
      841 catttaggcg cataagctgt tcaaaatcta aaatcaacac atcatgtgta gtgtgataat
      901 agatattctc tttaagattt ccaacaatgg taattcggtc gattgaccac tgaattttta
      961 ggggggtgtc cataaaaggg acacttaacc gcctgttaga gggggctgtt aatttttccc
     1021 actcatttat gatcgtgcct tttttactca aatttagttc ctcctcaaag aaaaaagaga
     1081 ttggtggaaa gaattttcca gagttcacgt aactctaaaa aattcataac cagcaatctc
     1141 tagtcttgaa gaaacctgaa attattcgta taatgaattt gagttacgga gctagtgtga
     1201 ttagtttccg taaaggtcga gaacgtgtcc agcgttgctc gactttattt ttttgctctt
     1261 ttttcagttt atttatttga taactcaata atagcacttc tctttagcta tgcaaatatc
     1321 caaaaacata aaaccgcacc ctttgaaaag ggcgccccca aacttcgcta acgctaagtt
     1381 ggccaaaaaa tggacttgcc attttttagc aaatgtcagc ttcagggatt agtggtttag
     1441 ccgtcaactc cttatcctcg gcacagaccg cctccggtac cgttgactgc accgtataac
     1501 taccactcca tctcattctc agaacgccct atattacgtt ctggggcatt ctgctgacta
     1561 gccaacgttt tctcttgatc taatattttt agctcttcag atattcccat atctttttct
     1621 acaagcccaa aacgaattga taaacgagtg attgattttt gaaatgcgtt tttcagttga
     1681 gttaaccgcc gacgcaaaga acgattttct tccttcagct ttttgttttc agcaacaacc
     1741 gctgacacat caaccttttg ttgatttttc aaaaaagaat tttcttgttc taacgccatg
     1801 tttttatcaa ataaagcgat atttttatct aatgtatttc caagcgattc attcgccata
     1861 tcagcatatt ttttgctgtt cgtagcatta gacgcttttt gatacaaatc tacaaaatca
     1921 gcactagata agcgataaga accatctgat aatttttcaa aactattgag tggcacagga
     1981 tctttttgaa atacaacagc cagctctttt tccaaatcga taatcgattt tttctcttct
     2041 tcaattttcg ccttctcaga agccaccaga gccttctcac gctcgttttt ttctctttgc
     2101 ttagaaatat atacctcatt tccgcagaaa tgctctcacg ctcttttaca gccgtttggc
     2161 gcaattcaga aatttcactc atgatttctt tgtattcgtg aatatcttta attttgttgg
     2221 taccgacaat atcccttttc caaccgtaat cattcattaa tcgttctata gagtcaactt
     2281 cttgatttct aaaattattg aaaagcactc gaccattatc tttatcagcg tgtatccctt
     2341 gttgaaccag tgctttatta aagctcggct gcttttgaac accccgttta taaccttcag
     2401 caaccggcac aatattcaag tgcaggtgcg gacttatttc gtcattatga ataacagcat
     2461 tataaacagc caaattaggg tttctctctt gaaactcctt gtaatactga accaaaattt
     2521 tattggcaat cactcgattt tgttcagctt gttgtttcga tatgccagta gaagaaccat
     2581 ctgctcgatt tgtctggaaa tcatctaaaa tgcctatttg cacaataaat tctcgttgag
     2641 gttccaactt tttatccttg cgcactttcg ctaaatagtc ctcgattttt ctatcggctc
     2701 ttttttgttt cgcattatat ttttctacca cttcgccaaa caattcctca tatttatctg
     2761 ctagattcgt ctgctctaaa taaatatttt catccgattt cgtgaagtca atatgcttat
     2821 gccaatcatt ggttttctgg ctatcagtta actcacgatt attatgagaa atacttgtat
     2881 tcttcgttcc ttttttaaat gaaatactaa accccaagtt aaaaccctcc ttcgcgctgt
     2941 cgctaataaa aagagtgtaa acctttctgt tactctttgt caaagagtaa cattttccta
     3001 attgtgacat ggctgtcaca attccaaatg ctctccgagg gtattcgctg tcacaagtga
     3061 caacgaaaaa aggagccgaa agcgtgtcac gctctcaact ccttttacgc tttattttgc
     3121 ttcacgcaaa ataatcgctt atcgtaaact cacgtcatta aacattgacg taaatttact
     3181 ctcactcatc tgactttttt tactcggtat cactccgagt aagccgtcag attcattggg
     3241 ataatctcgt tcgcttggcg ctgatttttc atcagcaagc cactcattat ccactgattt
     3301 ttcgtgttgc tgatcgtcag aaattgacga taaccaccgc tcaaaatcat caaaagattc
     3361 aaatccaaaa tgcttccgaa gtgccttacc catttcagca ttttccttct caatcaatcg
     3421 ttttttctgt tgacgaagtt ttgcctgttc ttttttcaat ttttcttctt gtgctttaat
     3481 atctgctaaa gtcattccca agatttacag ctccttgcct tttgatttat ttcgataaat
     3541 aacaccaatt tgatttaatt gcataacata agttaaaata ttcagccaaa attccttttc
     3601 agattcatct tctgtttcgg ctattttacc gtaaacaaat ttatcagtaa tcaaagaaga
     3661 atttgctagg cctacattga ttgtagaatt gagaacgtcc atcattctct caagcatttc
     3721 actataatta tcttcatccg gcaaattcaa ataatcagct aatcgttcat acatcaattc
     3781 aattctatca actgtctctt ctcttaaatc aattttatcc atgttacacc tcatttccaa
     3841 aactgccacc atttccgatt ctttaatttt cgatacacct aattcatcag caagattttt
     3901 tatggtcatc ttttctgaca aatcagtcat tagcttctcc actactttca gctaccgcat
     3961 aaatatattt aacggcgtgc ttagggataa taatcggaga gtcaatttta ttatttttca
     4021 aaatcaattc atattgcgtt acatcaagta acttaccgga catttttttg ctatcc
//
LOCUS       DAFBVQ010000125         3956 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.131, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000125 DAFBVQ010000000
VERSION     DAFBVQ010000125.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3956)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3956)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3956
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.131"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..156
                     /locus_tag="LLC22_002795"
     CDS             <1..156
                     /locus_tag="LLC22_002795"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392734.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="4Fe-4S binding protein"
                     /protein_id="HBK5435993.1"
                     /translation="DKDKCINCGKCKKVCQMNKDSVENCNHLECIRCGRCKNACPVDA
                     ISYGVRK"
     gene            175..1452
                     /locus_tag="LLC22_002796"
     CDS             175..1452
                     /locus_tag="LLC22_002796"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_009898531.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435994.1"
                     /translation="MIKNAIAYITRKKNRTLIIFIILTIVLSCLYSCLTIMKSSNEIE
                     KALYESSNSSISITKKDGKYFNVNQFKDIEKLKEIEEKIIQYDGLAKLKDAKVVSGEQ
                     RINREDLSDEFKNVVSLEATNNTKRNILFSSGVFTIKEGKNIEENDKNSIIVHEEFAK
                     QNNLKLGDEVDLELLDIEKSGKIKSHKFKIIGIFSGKKQETYTGLSSDFSENMVFVDY
                     STSQEILNNSENNEIANKILMYSGSAESTDLALNKLKELKIDESKYFVEKDSNAFEES
                     LESVSGIKYIIKVMTYSIMLGGMVVLSLILILWLRERIYEIGIFLSIGTSKIQIIMQF
                     IFELIFISIPSIISSLFLGNVLLKVIVDGFINSEDSMISGGSLINNSSFMSNITTLGQ
                     SYLILISIIVLSVVFASSLMLIKKPKEILSKIS"
     gene            1462..2118
                     /locus_tag="LLC22_002797"
     CDS             1462..2118
                     /locus_tag="LLC22_002797"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_004612033.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter ATP-binding protein"
                     /protein_id="HBK5435995.1"
                     /translation="MDILEIKNVAYSYANSKEKVLSGVNQKFELGKFYAIVGKSGTGK
                     STLLSLLAGLDKPQTGKILFKNEDIQNKGYSNHRKNNISLVFQNYNLIDYLSPIENIR
                     LVNKSADESILFELGLDKKQIKRNVMKLSGGQQQRVAIARALVSDAPIILADEPTGNL
                     DSVTAGEIINILKTLAKDRNKCVIVVTHSKEVADSADIILELSGKKLKKVNKMNLEVE
                     "
     gene            2118..3494
                     /locus_tag="LLC22_002798"
     CDS             2118..3494
                     /locus_tag="LLC22_002798"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017647836.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease"
                     /protein_id="HBK5435996.1"
                     /translation="MIKNAFAYVTRKSLKSLIIILVILSMSTLSLISLSIKDATDRAS
                     KETFANITNSFSMEINRQVNPGTPRGGGNVKGEDIKKISQTDSIDSYVKRINSVADLV
                     DYDIIETQETLANQSPERAKNFKRTVMLTGVNDSTKETKFVSEAYKLVEGKHLENEDK
                     NKILMHKDLAEKNNLKVGDKIKIKSNLFDADNEKGADETVEVEIKGLFDGHNSGVVSA
                     AQELYENTLITDIHTAAKVYGNTEDTAVYQDATFFVKGDKNLDSVIKDLGKLDINWRE
                     YNLIKSSSNYPALQQSISGIYSISNKLFFGSLIFAGVVVSLLLFLWMNARKKEIAVLL
                     SLGISKLEIFGQFLIEMVFISIPAFVGSYFLAQYTADKLGNNILNKVTGDIAKQIAKQ
                     SASSQLGGGAEAEGFNKTLSSLDINVLPKFMIYVVIFMSLVLLVSLIISSFNILRRNP
                     KELLIDNN"
     gene            3624..>3956
                     /locus_tag="LLC22_002799"
     CDS             3624..>3956
                     /locus_tag="LLC22_002799"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBK5435997.1"
                     /translation="MARKKRNPDAEKLAESILNTYQPESVEDMQDVLKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKKHDNRRNGYGNKTLKTSFGKVNIDVPRDREASFEPELIP
                     NRKRDVSDI"
BASE COUNT         1594 a          423 c          693 g         1246 t
ORIGIN      
        1 gataaggata agtgtattaa ttgtggaaaa tgtaaaaaag tttgccaaat gaataaagat
       61 tcagttgaga attgcaatca tctggagtgt atcagatgtg gacgatgtaa aaatgcttgt
      121 ccagtggatg caattagtta tggagtaaga aaatagagag gagtagttag gaaagtgata
      181 aaaaatgcta tagcatatat tacaagaaag aaaaatagaa ctttaataat ttttatcata
      241 ttaactatag ttctttcttg cttgtattct tgtttaacaa taatgaaatc aagcaatgaa
      301 atagaaaagg ctttatatga aagttctaat tcttcaatat caataacaaa aaaagatggt
      361 aaatatttta atgttaatca atttaaagat attgaaaaat taaaagaaat tgaagaaaaa
      421 ataattcaat atgatggatt agcaaaatta aaagatgcta aagtagttag cggagaacaa
      481 agaataaata gagaagattt atctgacgaa tttaagaatg ttgtttcact cgaagctaca
      541 aataatacta aaagaaatat tttatttagt agtggagtat ttacaattaa agaaggtaaa
      601 aatatagaag aaaatgataa gaattcaatt attgttcatg aagaatttgc taaacaaaac
      661 aatctaaaat taggtgatga agttgatctt gaattactag atattgaaaa aagtggaaaa
      721 ataaaaagtc ataaatttaa aattataggg atcttttctg gtaaaaaaca ggaaacatat
      781 acaggattat cttctgattt tagtgaaaat atggtgtttg tagattattc aacaagccaa
      841 gagatattaa ataattcaga aaataatgaa attgcaaata aaattttaat gtattctggt
      901 agtgcagaat ctacagactt agccttaaac aaattgaaag agcttaaaat tgatgagtca
      961 aagtattttg ttgaaaaaga ttctaatgcg tttgaagagt ctttagagtc agtgagtgga
     1021 ataaaatata taataaaagt aatgacttat tctattatgt taggtgggat ggttgttctt
     1081 tcattaatct tgattctatg gttaagggaa agaatttatg aaataggtat attcttatct
     1141 attggaacat ctaagataca aattataatg caatttatat tcgagttaat attcatatcg
     1201 ataccaagta taatatcttc cttattttta ggaaatgtat tactaaaagt aattgtagat
     1261 ggattcatta actcagagga ttcaatgatt tccggtggaa gtttaataaa taatagtagt
     1321 tttatgtcaa atataacaac acttggacaa agttatttaa tattaataag tattattgtt
     1381 ttatcagttg tatttgcttc ttcattaatg ttaatcaaga agcctaaaga aatcttatca
     1441 aaaataagtt aggagaaaat aatggatata ttagaaataa agaatgtagc atatagttat
     1501 gcaaattcta aagaaaaagt tttgtcagga gtaaatcaaa aatttgaact tgggaagttt
     1561 tatgcgatag taggaaagtc aggaacagga aaatctacac ttctttcctt acttgctgga
     1621 cttgataaac ctcaaacagg aaaaatattg tttaagaatg aagatataca aaataaagga
     1681 tatagtaatc atagaaaaaa taatatatct ttagtatttc aaaactataa tttaatagat
     1741 tatttatcac caattgaaaa tattagatta gtaaataaat cagcagatga aagtatcttg
     1801 tttgaactag gtttagataa aaaacaaata aaaagaaatg ttatgaaatt atctggtgga
     1861 cagcaacaaa gagtagctat tgctagagca ttggtatcag atgctccaat aatactagct
     1921 gatgagccta ctggtaatct agacagtgtt actgctggag aaataattaa tatattaaag
     1981 acattagcta aagatagaaa taaatgtgta atagttgtaa cacatagtaa ggaagtagca
     2041 gattctgcgg atatcatttt agaactaagt ggtaaaaagt tgaaaaaagt aaataaaatg
     2101 aatttggagg ttgaataatg ataaaaaatg catttgctta tgtaactaga aaaagtttaa
     2161 aatcattaat tatcatatta gttattttat ctatgtcaac tttaagtctc attagtttat
     2221 ctattaaaga tgctacggac agagcttcaa aagaaacatt tgctaatata acaaatagtt
     2281 tttctatgga gataaataga caagtaaatc caggaacacc tagaggtggg ggaaatgtaa
     2341 aaggtgaaga tattaaaaag atatctcaaa cagatagtat agactcctat gtaaaaagaa
     2401 taaacagtgt tgcagattta gttgattatg atattattga aactcaagag actcttgcga
     2461 atcaatcacc tgaaagagca aagaatttta aaagaacagt tatgttaact ggggttaacg
     2521 actcaacaaa agaaacaaaa tttgtatcag aagcatataa attagtagaa ggaaagcatt
     2581 tagaaaatga agataaaaat aaaatcttaa tgcataaaga tttagctgaa aaaaataacc
     2641 ttaaagttgg agataagata aaaataaaat ctaatttatt tgatgctgat aatgagaaag
     2701 gtgcagatga aacagtagaa gtagaaatta aaggtctatt cgatgggcat aatagcggtg
     2761 tagtaagtgc agcacaagaa ctatacgaaa atacattaat cactgatatt catacagctg
     2821 ctaaagttta tggtaatacc gaagatacag ctgtatacca agatgcaaca ttctttgtaa
     2881 aaggtgataa gaatcttgat agtgtaataa aagatcttgg gaaattagat ataaattgga
     2941 gagaatataa tttgattaaa agttcatcaa attaccctgc attacaacaa tctatatcag
     3001 gtatttactc aatttcaaat aaattatttt ttggctcatt aatatttgca ggagttgtag
     3061 tttcattatt attattctta tggatgaatg ctagaaagaa agaaatagca gtattactat
     3121 cattaggtat atcaaaatta gaaatttttg gtcaattcct aattgagatg gtatttatat
     3181 caatccccgc attcgttggt tcctatttct tagctcaata tacagctgac aagcttggga
     3241 ataatatatt gaataaggtt actggtgata tagctaaaca aatagctaaa caatctgcat
     3301 ctagccaatt aggtggtggg gcagaagctg aaggatttaa caagacatta tcaagtttag
     3361 atatcaatgt attacctaaa ttcatgattt atgtagttat atttatgagt ttagtacttc
     3421 ttgtatcatt gattatttct tcattcaata tattaagaag gaatccaaaa gaattattaa
     3481 ttgacaataa ttaaaatttt cggtgctttt tagcaccaaa aatgagagtg taatataaac
     3541 cgtgtaagta accatcaatc ctaggcgggt ggttgcttca cggtttttat ttttctaaaa
     3601 taagatcaag aggtgattac acgatggcta gaaagaaaag aaatcctgat gctgagaagt
     3661 tagctgaatc cattttgaat acttatcaac ccgaatctgt agaggatatg caagatgttt
     3721 taaaagatgt gtttggtccc ttatttgaaa aaatgcttca aggagaattg aataaccatt
     3781 tagggtatga cgcccattct aaagagccaa agaaacatga caatcgacga aacggttatg
     3841 gcaataagac gcttaaaacg agctttggta aagtaaacat tgatgttccc agagaccggg
     3901 aggcttcttt tgaacctgag ttgattccta atagaaaacg agatgtctcc gacatc
//
LOCUS       DAFBVQ010000126         3930 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.132, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000126 DAFBVQ010000000
VERSION     DAFBVQ010000126.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3930)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3930)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3930
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.132"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            171..515
                     /locus_tag="LLC22_002800"
     CDS             171..515
                     /locus_tag="LLC22_002800"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629150.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="carboxymuconolactone decarboxylase family
                     protein"
                     /protein_id="HBK5435998.1"
                     /translation="MAEKQTAGRDQLGDFAPKFAELNDDVLFGQVWSREELSAHQRSI
                     ITISALISGGNFEQLPAHLKIGKQNGITSEEIAEIITHLAFYVGWPKAWSAFSLAKEI
                     YLEENSEDKKEA"
     gene            516..935
                     /locus_tag="LLC22_002801"
                     /pseudo
     CDS             516..935
                     /locus_tag="LLC22_002801"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297629.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="cupin domain-containing protein"
     gene            complement(1027..1377)
                     /locus_tag="LLC22_002802"
     CDS             complement(1027..1377)
                     /locus_tag="LLC22_002802"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330645.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5435999.1"
                     /translation="MEKELSKRIIDELLTYLYSHEITEIRIGVEFAEEGLFIEIQGTA
                     ETQPEDLDVLADLLNNPRDPSMEIYYQELLGNPRHDREDYHLLGSLIDDVEIMYAQPI
                     INIKIFRRASHSYY"
     gene            complement(1343..2674)
                     /locus_tag="LLC22_002803"
     CDS             complement(1343..2674)
                     /locus_tag="LLC22_002803"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336484.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF1576 domain-containing protein"
                     /protein_id="HBK5436000.1"
                     /translation="MENETDVIYIHPQKRIVSQKRKYFYLGFTGVFFLFIGLLSNTPT
                     DNWSGLLTILTSPSNLLTDYFALGGFGSAFINVGILTLLSVLLAYRHKVILNGPLFAS
                     ILTVTGFSFFGKNLYNSISIILGVYLYAVFVNKPFSQYIMIGLFGSALSPVVSYITFG
                     MRFPLLIGILLGNLAGIAIGLLLPPLAAQTLVFHRGFTLYNIGFTSGLIAMTFTAVLR
                     LFSYSIVENTLVFNEYHFPLIWIIFGFFSLTVGIGFYYNSFRLLGIREIFDSSGKLTT
                     DFIANSGIGATLINIGLVGLMLSSYVLLVGGQLNGPVIGAILSAVGFSAFGCHLKNSF
                     PILVGIFIASLFGTFHEITSTGMLVAAVFGTGLAPISGFYGSFYGVIAGVLHIALVHN
                     VSTLHGGLNLYNSGFSTGFVAGILVPILDNFTAVRKEKKTLGKRIIKKNHR"
     gene            2930..3496
                     /locus_tag="LLC22_002804"
     CDS             2930..3496
                     /locus_tag="LLC22_002804"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324998.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TetR/AcrR family transcriptional regulator"
                     /protein_id="HBK5436001.1"
                     /translation="MRRKVYTKDQILKAAYDVVAKEGFKGFTARNIAKKMGISTQPIY
                     LEFKNMEDLKNTLLDSIFEQLKEDVFPIERTGDKIIDLGLNYIYFAKKHHSLYMALYI
                     DEHGDGKKMHDFSYNYFREIVKEDERYNQLSDEYVDALHTGTWVAVTGLASLMSSNIM
                     HPTEEQIIALIKRTIDSILALDNPEIIR"
     gene            3641..3728
                     /locus_tag="LLC22_002805"
     tRNA            3641..3728
                     /locus_tag="LLC22_002805"
                     /product="tRNA-Ser"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:3673..3675,aa:Ser,seq:cga)
BASE COUNT         1436 a          677 c          761 g         1056 t
ORIGIN      
        1 taaaaaaagc gttagcaact atgcttaaaa agcatatcga ctgaataaac taagcattgg
       61 acaggctgaa agactacatt taaaatgaaa tgcgaagaaa caatagaaaa taaagttgcc
      121 ttagaaccat agttgaatca cctaacagtc gtgaagggag aataagagaa atggcagaaa
      181 aacaaaccgc aggacgagat caattaggag attttgcacc aaaatttgca gaattgaatg
      241 atgatgtttt atttggacaa gtatggtcca gagaagaatt atctgctcat cagcgtagta
      301 tcatcaccat atctgcatta atttcaggag gaaattttga acaattgcca gctcatctga
      361 agattggcaa gcaaaatggc attactagtg aagaaatagc agaaatcatt acccatttag
      421 ctttttatgt aggatggcca aaagcttggt cagcttttag tttagcaaaa gaaatctatt
      481 tagaagaaaa tagcgaagat aagaaagagg cgtaaatgac gacaaaacac gaagaaatac
      541 acaatggcgt gatttttcca gcaggtgaaa aaaacgaagc ttacgctcaa gtatttaccg
      601 ggtaaagcta tctgaatatg ttagtgaatg atcccgaagt ttctgttggt gtaggtaatg
      661 taacttttga accaggttgt cgcaatcact ggcatgtcca taaagacggc tatcaaatct
      721 tacttgtgac cggaggagaa ggctggtatc aggaagaagg aaagccagca agacgattaa
      781 tggctggaga tgtcgtcgta acgcacaaag ggattaaaca ttggcatggt gcgacaaaag
      841 acagttggtt tgaacatttg gcgatcactg ctggtaattc agagttttta gaacctgtaa
      901 cagatgaagt gtatgaagga ttggaaaatc aataatgtca agcttgaaca gctcctgaaa
      961 gtagatttta atcgaacttt caggagctgc ttttttgatt cagtctttta taaatagaaa
     1021 atagggttaa taataggaat gagaagcacg tcgaaagatc ttaatattga taatcggctg
     1081 ggcatacatg atttccacgt catcaatcaa actacctaac agatgataat cttcccgatc
     1141 atgtcgggga ttacctaata gttcttgata atagatttcc atactagggt cccgaggatt
     1201 gttcagcaaa tcagcaagta catctaaatc ttctggctga gtttctgccg taccctgtat
     1261 ctctatgaaa agcccttcct cagcaaattc tactccaata cgtatttcag ttatttcatg
     1321 ggaatataaa taagtaagaa gctcatcgat gattcttttt gataattctt tttccaagtg
     1381 tctttttttc ctttctgaca gcggtaaagt tatctagtat cggtacaagt atacctgcaa
     1441 cgaaaccagt tgaaaaacca ctgttatata gatttagtcc tccgtgcaaa gtgctgacgt
     1501 tatggacaag agcaatatgt agtacaccag ctattacacc gtaaaaactg ccgtaaaaac
     1561 cgcttatggg cgcgagacct gtcccaaaca cagctgcaac aagcatgcca gtactggtga
     1621 tctcatgaaa agttccaaac aaagaagcaa taaatattcc gactagtatc ggaaaactgt
     1681 tttttaaatg acaaccaaaa gcactgaaac ccaccgcaga taaaatagca ccgatgacag
     1741 gtccatttaa ctgaccgcca accagcaaaa cataagaaga cagcatcaga ccaactaagc
     1801 ctatgttgat caaagtagca ccaataccag aattagcaat gaaatcagtt gtcaattttc
     1861 cagatgaatc gaaaatttct cgaatcccca aaagccgaaa ggaattataa tagaaaccaa
     1921 ttccgactgt cagcgaaaaa aagccaaaaa taatccaaat gagaggaaag tgatattcat
     1981 tgaaaaccaa tgtattttcg acgattgaat agctgaataa cctcaaaaca gcagtaaaag
     2041 tcatcgcaat caacccagag gtgaatccaa tattataaag tgtgaatcca cgatggaaaa
     2101 ctaaagtttg agcagctaag ggcggaagaa gtagaccaat tgctatgcca gctaaattcc
     2161 ccaataaaat acctatcagt aaaggaaaac gcataccaaa agtgatataa ctaacgaccg
     2221 gtgataatgc gctaccaaac agtccgatca tgatgtactg agaaaaaggt ttattgacaa
     2281 atacagcgta tagatacaca cctaaaatga ttgagataga attataaagg tttttgccaa
     2341 aaaaagagaa accggtaact gttagaatcg aagcaaataa gggaccgttt aaaatcacct
     2401 tgtgccgata agctaaaagc acagaaagta aggtcaaaat ccctacattt atgaatgcgc
     2461 ttccgaaacc gcctaaagca aaataatctg tcaaaagatt gcttggcgag gtaagaatag
     2521 ttagcaatcc actccaatta tcagtaggag tattagaaag caagccaata aaaagaaaaa
     2581 aaacacctgt aaaaccaaga taaaaatact ttcttttctg tgaaacgatt cgtttttgag
     2641 gatgaatata aataacgtca gtttcgtttt ccattacaca ccttcttttt cattttcttt
     2701 aactataact tgaaatgaaa gatttggaca actatcattt aggtcaaaac taaaaatgta
     2761 agggaaccca ttgaatttaa ccaaattttt ttaattttgc aaaaaaaagt taaagaagac
     2821 tgaaaaaaaa tttaaaatat aacgttttga gtaaaatgtt tgcaaaaaat gctaaaaata
     2881 gggtacaata aaacaacata tactgcagta aagaagtggg ggagttttaa tgagaagaaa
     2941 agtctatacc aaggatcaaa ttctaaaagc tgcttatgat gttgttgcaa aggaagggtt
     3001 taaaggattt actgcgagaa atattgctaa aaagatgggg atttcgacac agccgattta
     3061 tctggaattc aaaaacatgg aagatttaaa aaatacgttg ctggattcta tctttgaaca
     3121 actaaaagaa gatgttttcc ctattgaacg tactggtgat aaaatcattg atctcggttt
     3181 gaactatatc tactttgcaa aaaagcatca tagtctttac atggcattgt acattgatga
     3241 acatggggac ggaaagaaaa tgcatgattt ttcatacaat tatttccgtg aaatagttaa
     3301 agaagatgaa agatacaatc aattatcgga tgaatatgtc gatgctctgc atactggtac
     3361 atgggtagca gtgactggct tagcgtcatt gatgtcatca aacatcatgc atccaacaga
     3421 agaacaaatc attgcactga tcaaacggac aattgactcg attttagcat tagataatcc
     3481 tgaaataatc agatagtgtt ctatcagtat gaatttgatc ggtaagtccg ttggctgcaa
     3541 actgtcaatg gacttttttg ctaaaaaaag cgatttctgt tatttatcta ttagaaatag
     3601 gcttgacatt tcgtgaaaaa agtttaaaaa tagtacttac ggaaggttgg cagagtggta
     3661 atgcaccgga ctcgaaatcc ggcgaaccgg ctaataccgg cgcgcaggtt caaatcctgt
     3721 accttcctta tatcaacgat tagaggttgt gaagaagctg tcctgcatca agtaataaga
     3781 acggccaaac aaaaatagct tttcctattt tttcgtttga ttgggcttat taccgcagat
     3841 gcaagctttt gaacaccgtt tgttcggaat aaggggctgt gacaagactt ttgtcacagc
     3901 cccttattgt tgtactttta acctacaata
//
LOCUS       DAFBVQ010000127         3927 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.133, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000127 DAFBVQ010000000
VERSION     DAFBVQ010000127.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3927)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3927)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3927
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.133"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LLC22_002806"
     CDS             complement(89..1174)
                     /gene="xerS"
                     /locus_tag="LLC22_002806"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016177643.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine recombinase XerS"
                     /protein_id="HBK5436002.1"
                     /translation="MKNTEIYQKIDTIILHMPDYIKDFVQDREDKDQSPRTTLEYLKN
                     YKLFYEWLLSESIVPDTSITSIRQLTAYDLNLYKSHLKRRTKENVKKETTKTKLKDNN
                     NLGLSTSTINRNITALKVLFKYLSKSSNNPLGKPYLENNPMDQVATITDKTTLAARAN
                     AIEKKLFLDEDTQNYLDYIANEYKKTLSKRALIYYQRDVERDLAINALILGSGLRLSE
                     VVNINLEDLSLEKNNVVVTRKGNKRDAVNIAAFAMEYLANYLAIRKERYKVTENEKAL
                     FLAIYQGEAKRISGIAIERMVAKYSKGFRVQVSPHKLRHTLATRLYQQTNSLVLTAQQ
                     LGHTSTNTTTLYTHIDNAATIDALNAL"
     gene            complement(3250..3768)
                     /locus_tag="LLC22_002807"
     CDS             complement(3250..3768)
                     /locus_tag="LLC22_002807"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_013852041.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ClbS/DfsB family four-helix bundle protein"
                     /protein_id="HBK5436003.1"
                     /translation="MRTYKNKEELKKEINRTYTKYILEFETIPEELKDKRVEEVDRTP
                     AENLAYQVGWTNLILKWENDERNGLSVKTPSDQFKWNQLGELYKWFTNTYAHLPLKEL
                     EEILNRNIDDINMMIDSMSDEDLFTAHKRKWADEATKTAVWEVYKFIHVNTVAPFGTF
                     RTKIRKWKRLAL"
BASE COUNT         1271 a          642 c          591 g         1423 t
ORIGIN      
        1 taaaaatgat aatgaagctt gcctttaaag ttgggctttt atctaatttt agagacaggc
       61 ttcattatta tactattttt tactacattt acaaagcgtt caaagcatca attgtagctg
      121 cattgtctat atgagtatat aaagttgttg tatttgtact tgtatgtccc aattgttggg
      181 cagttaatac caatgaattt gtctgttgat agagtctagt agccaaagta tgacgtaatt
      241 tatgtggact gacttggact ctgaatcctt ttgaatattt tgctaccatc cgttcgattg
      301 caataccgga tatacgcttg gcttctcctt gataaattgc tagaaataaa gctttttcgt
      361 tttctgttac tttgtatcgt tctttccgaa tagctagata attagctaaa tattccattg
      421 caaatgctgc tatatttact gcgtctctct tatttccttt tctagttact accacattat
      481 tcttttctaa agataggtcc tctaaattaa tatttacaac ctcggagagt cttaatccag
      541 atcctaaaat caatgcattg atcgccaggt ctctttctac atctcgttga taatagatca
      601 aagctcgttt gctcaaagtt tttttatatt cattggcaat ataatctaga taattttgtg
      661 tatcttcgtc tagaaataat tttttctcga ttgcgtttgc acgggcagct aacgtagttt
      721 tatctgtgat agttgctact tgatccatag gattattttc taagtatggt tttcctaaag
      781 gattattgga acttttcgaa agatatttaa atagaacctt taatgctgtg atatttctat
      841 tgatagtaga agtagataga cctaagttat tattatcttt gagcttagtt tttgttgtct
      901 ctttttttac attttccttt gtgcgacgtt tcaaatgaga tttgtacaag tttagatcat
      961 aggcagttaa ctgtcttatc gaggtgattg aagtatcggg aacgatagac tcactcagaa
     1021 gccattcata aaagagctta taatttttta gatattctaa agtagttcga ggtgattgat
     1081 ctttatcctc acgatcttga acaaaatctt ttatataatc gggcatatga agtatgattg
     1141 tatctatttt ttgatatatt tctgtatttt tcatgttatt catcctttcg ataagtaggg
     1201 gagaggagta tctctataat tggactatac caattataga gtgttttgtc aattggtata
     1261 ctctgaaatt tattaattta tttcaaaaaa gcagataaat aggtatagat ttaataattt
     1321 aaaataaatg gtatacatga ataggaaagg aaacagaagg aggcaatctt aattttttaa
     1381 attgtctaaa ttatatagaa agaacaatct ttctatataa ttagacataa gagagactac
     1441 ggttgatttg atattaacaa gcgtatatga atgtatatac aaataaaaaa ggggagggag
     1501 aagttaaaga aaattcagag aagtggggca ctcagtagta ttaacaattt aaaaggaatt
     1561 tcttaaagaa aatgggttgc atcctggaga tacaattttt ttagataaag aaaaaattca
     1621 agcaacaatt caaaaaaatc ttaactgctg agattgatgt agcaatatct caatcatcaa
     1681 caaagtacga tcctgccttt caaaagctta ttgataaatg tttattcatt ataaaaataa
     1741 aagaaaaatt tatgtcagct tttttcatca aagtggtaat gataattcgt ctattaattg
     1801 tattttttag gaaatatggt ataattgttt taacgaaaag gtaattcatg atacaccaaa
     1861 aaccactagc tggcgggcta gtggttttct tttacgttct attcagatta acgggtaggc
     1921 ttactgtctt ttttggcaat aattttgcaa tcaagccatt tacagatgta atgcgcggat
     1981 acttctgcta agattgcaaa aaacatatcg aaaaggtaat tcataataca acctcctccc
     2041 cttgccataa taggccgggg tagcagacag cataaatatt ataccataac tgaaaatttc
     2101 attttagtac atttcaatat attgatgaac cagcacaata aaacatgcca tgactaacag
     2161 aaaaaaactt attaaaccag atataacttg taaacatcca actatataga aaacgtaaat
     2221 tttctatata gttggattaa gataacgact atttatttta tcatattttt actataccct
     2281 atacttttac ttggtatatt tatgaataat cgcaaattta cccctatact actagtttgt
     2341 aagttagatt aataaaaata ctaaagttat ttgttctttt attaaataca cctacaactt
     2401 ataaattgat ggtatttaga taacacgaaa gaataaaaat aacagctgat agtaaagttt
     2461 gttgacgatt gctactcaat cgaaagtgag ttagtgcgta tgaacttgct tctgaaaact
     2521 tatgaaatga aagacctttt acatcttgca gaaatcggta ctgggattaa actaagcaat
     2581 aaaaactaat gttcccctca ttctttgaac ttctactatt tgatttattt attctgataa
     2641 atgacgattt caccttcagg atcttcaaat cccgtataga atttatttaa gatctcttca
     2701 gtatcagtaa taggataggc gataggccac ataccctttg atggttagaa taaactgctc
     2761 aaaatctgta tcgtatgttg gctttagcat attaacaaag gctatctcca aattataaac
     2821 cataagcgtt gaatcgttct taacaatttc aattcttcct aacccaaagt cagaagatat
     2881 aattaccgga cttgccttac ccttcatgtg ggttgttgag attccatatt taaagggaat
     2941 tgtcggtact atcggcggtc tgaaaaacat cccaaaaata aaaaaatctt tcccctgcta
     3001 gtctcctaag tccctttgta gcggatatgg caccataatc tcattttatc gaagtgagtc
     3061 atggtttatc tgttggccaa ccaaaattga tacaatctaa cgatgcaccc tctacggcat
     3121 tctaggggag tgcacttgca ttcacccaat aaaaaccggc agttagcaaa gaacttatgt
     3181 agtcgtatgt tcttactgtt aacatacaag aggtctcctt tccacaattg cttagcagta
     3241 aacgggaatt tacaaagcta atctcttcca ttttcttatc tttgttctaa aagtcccaaa
     3301 tggagcaact gtatttacat gaataaattt atatacttcc catacagccg ttttggttgc
     3361 ctcgtctgcc cattttcttt tgtgtgcagt gaatagatct tcatcactca ttgaatcaat
     3421 catcatgtta atatcatcaa tattacgatt gagaatttcc tctaattctt tcaatggtag
     3481 atgtgcatag gtatttgtaa accacttata taactctcct aactgattcc atttaaattg
     3541 atcagaaggc gttttaacag ataatccatt tctttcatca ttttcccatt ttagaattaa
     3601 attcgtccaa ccaacttgat atgctaaatt ttcagcaggt gttctatcca cttcctcaac
     3661 tcttttatcc ttcaattctt caggaatagt ttcaaattct aaaatatatt tagtataagt
     3721 cctatttatt tcttttttta attcttcttt atttttatat gttctcatta tattacctcc
     3781 ataaattcct aattgtctcc tttaattcat ctataatttc atccacgata ttttaatccg
     3841 ttctacaatg catatctgat atgcattgac tgtctaactc atatgtgaat gatttataaa
     3901 atatcccaac gtctcatcta aagaaat
//
LOCUS       DAFBVQ010000128         3735 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.134, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000128 DAFBVQ010000000
VERSION     DAFBVQ010000128.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3735)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3735)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3735
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.134"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            11..478
                     /locus_tag="LLC22_002808"
     CDS             11..478
                     /locus_tag="LLC22_002808"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321263.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436004.1"
                     /translation="MIGMTEELAKEKSFSPVRLFIKTFRQFWLKGFFYWLFAWIVSVI
                     MIFDCFFFIRFSYGKWLIPLFVLLACLSVSFSINYWYFQVRNPASKPNQVLRIAFYYT
                     LKKWYVSLLDFLLLTSLFLFFFVKPQWCILLGPSIVFGLIYFNNRKLMRTMDL"
     gene            683..2347
                     /gene="alsS"
                     /locus_tag="LLC22_002809"
     CDS             683..2347
                     /gene="alsS"
                     /locus_tag="LLC22_002809"
                     /EC_number="2.2.1.6"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352535.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate synthase AlsS"
                     /protein_id="HBK5436005.1"
                     /translation="MDEKMKQGSKSVVESLINHHVDYVFGIPGAKIDGVFNELEDQGP
                     ELIVTRHEQNAAFMAQAIGRITGEPGVVIATSGPGASNLATGLVTATAEGDPVLAIAG
                     QVKRSDLLKLTHQSMDNAALFQPITKYSAEIQDPETISEVIANAYRMAKSSKKGASFI
                     SIPQDVVDAPVQGNVIKPLSDPKLGSASADDIRYLAERIREAKLPVLLVGMRGSSEKE
                     TLAIRQLVGKTALPVVETFQAAGVISRELEAHFFGRVGLFRNQPGDMLLKRSDLVIAI
                     GYDPIEYEARNWNAEKDARIIVIDEAPAEIDPFMQPERELIGDISATLDLLTGSLEPQ
                     QVSEDAKEYLASLQAELTERDIVQSKGEAGILHPLEVINTLQSKVTDDMTVTVDVGSH
                     YIWMARHFRSYEPRHLLFSNGMQTLGVALPWAISAALVRPNTQIVSVSGDGGFLFSAQ
                     DLETAVRKKLNIVHLIWNDGHYNMVEFQEKMKYQRASGVDFGPVDFVKYAEAFGAKGI
                     RATSVEELEKALEEGFATEGPVIIDIPIDYRDNEKLGETILPDQFY"
     gene            2360..3070
                     /gene="budA"
                     /locus_tag="LLC22_002810"
     CDS             2360..3070
                     /gene="budA"
                     /locus_tag="LLC22_002810"
                     /EC_number="4.1.1.5"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002333671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="acetolactate decarboxylase"
                     /protein_id="HBK5436006.1"
                     /translation="MTEKILYQHGTLGALMAGLMDGTETIAHILEKGTLGLGTLHGLD
                     GEVIFLDGVAYQGRSDGSVAQLDGSELTPYAAITDFTPDTSFSVSKTADGEQLKKDIL
                     VREAGENLFLAVKITGLFKNMHIRIMPKQEKPYRRLAKISESQPEFQQSNVQGTLVGF
                     FTPELFQGVAAAGFHLHFIDDTHTFGGHVMDFEVAEGKVEISRISSLVQHFPVDDPTF
                     VHETIDYADLAAEIQQAE"
     gene            3200..3697
                     /locus_tag="LLC22_002811"
     CDS             3200..3697
                     /locus_tag="LLC22_002811"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631901.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GAF domain-containing protein"
                     /protein_id="HBK5436007.1"
                     /translation="MWTEKQKKDAYEILLLQQQGLLEAEDNWLANLANSSALLNETLP
                     ETVFAGYYLFDGNELILGPFQGRVSCTRIKMGKGVCGESAEKQETLIVDDVKTHANYI
                     SCDSAAQSEIVVPMVKEGNLIGVLDIDCGVTKGYDEIDQAFLEKYVDLLLANFNINAF
                     SFINN"
BASE COUNT         1230 a          596 c          807 g         1102 t
ORIGIN      
        1 ttgcatcgtg atgataggta tgacagaaga attagcaaaa gaaaaaagtt tttcaccagt
       61 acgtttgttc ataaagacgt ttcgccaatt ttggctaaag ggattttttt attggctatt
      121 tgcttggata gttagtgtga taatgatttt tgattgtttc ttttttatac gtttttctta
      181 tggaaaatgg ttgattccgt tgtttgtttt acttgcttgt ttatcagttt cctttagcat
      241 caactactgg tattttcagg tgagaaatcc agcgtcgaaa ccaaatcaag ttctacggat
      301 agcgttctac tatacgttga aaaaatggta tgtgagttta ctagattttt tactattgac
      361 aagtttgttt ctcttctttt tcgtaaagcc ccaatggtgt attctactag gtccttctat
      421 cgtatttggt ttgatttact tcaacaatcg taaattgatg agaactatgg atctgtagac
      481 tttataaatt gaaactttca attaagaatg acagttttta tgtaaaaact gtcattcttt
      541 ttcatttttt gaaacatatg gctaaacaaa tgaaataaaa cgtgctatac ttttgaatga
      601 aacaggttta gaaactgtat caattatttg tgattatttc taactaataa ttaaaaataa
      661 agcataaaaa ggacgatgtt caatggacga aaaaatgaaa caaggttcga aatctgtagt
      721 agaaagtttg attaatcatc atgttgatta tgtattcggt ataccaggtg caaaaatcga
      781 tggtgtattt aatgaattag aggatcaagg tcctgaatta atcgtgactc gtcacgaaca
      841 aaatgctgca tttatggcac aagcaatcgg acgtattaca ggagagccag gagtagttat
      901 cgcaacaagt ggtcctggtg ctagtaactt agctacaggt ttggtaacag cgacagcaga
      961 aggtgaccca gttttagcaa ttgccggaca agtaaaacga agcgatctat tgaagttgac
     1021 ccatcaaagc atggataatg cagcactgtt ccagccaatc acaaaataca gtgcagaaat
     1081 ccaagatcca gaaacaattt cagaagtgat tgccaatgct tatcgtatgg ctaagagttc
     1141 aaaaaaaggc gcgagcttta tcagtatccc gcaagatgta gtggatgcac ctgtccaagg
     1201 gaatgtcatc aagccattga gcgatcctaa attaggttct gcttctgcag atgatatccg
     1261 ttacctagct gaacgcatta gagaagcaaa actaccggta ctattagtag gtatgcgagg
     1321 atcaagtgaa aaagaaacgt tagccatcag gcaattagtt ggaaagacag cattgcctgt
     1381 tgtagagaca ttccaagcag ctggagtgat ctcacgtgaa ttagaagcgc atttctttgg
     1441 tcgtgtgggt ttatttagaa accaaccagg agatatgctt ttgaaacgaa gtgatctagt
     1501 tattgctatt ggctatgatc caatcgaata tgaagcaaga aactggaatg cggaaaaaga
     1561 tgcgcggatc attgtgatcg atgaagcgcc agctgaaatc gatcctttta tgcagcctga
     1621 aagagaattg atcggtgata tctcagccac tcttgattta ttgacaggtt cattagagcc
     1681 tcaacaagtg tcagaagatg caaaagaata tttagcatct cttcaagcag aattaacgga
     1741 gcgggacatt gttcaatcaa aaggagaagc aggtatcttg catcctttag aagttattaa
     1801 cacgcttcag tcaaaagtaa cagatgatat gactgttacc gtagatgtag gtagtcatta
     1861 tatttggatg gcacgccact ttagaagtta tgaacctcgt catttgttat tcagtaatgg
     1921 tatgcaaacg cttggtgttg cattgccatg ggcgatttct gctgcattgg tgcgtccaaa
     1981 tacacaaatc gtatcagttt ccggcgatgg gggattttta ttctctgccc aggatttaga
     2041 aacggcggta cgtaaaaaat tgaatatcgt tcatttgatt tggaatgatg gacactacaa
     2101 tatggtagag ttccaagaaa aaatgaaata tcagcgggcg tcaggtgtag actttggtcc
     2161 agttgatttt gtgaaatatg cagaagcttt tggcgctaaa ggaatccgag ctacaagtgt
     2221 agaggaatta gaaaaagctt tagaagaagg atttgcgaca gaaggacccg taattattga
     2281 tattccgatt gattaccgtg ataatgagaa attgggagaa acaatcttac cagatcaatt
     2341 ctattaagga agtgtcgaca tgactgaaaa aatcttatac cagcacggga cattaggagc
     2401 tttgatggct ggcttgatgg atggaacaga aacgattgct catatattag aaaaaggaac
     2461 tctgggattg ggaacattgc atgggcttga tggtgaagtc atctttttag atggcgtagc
     2521 ttatcaagga agatcagatg gctcagttgc ccaattagat ggaagtgaac ttacccccta
     2581 tgcagcaatt acagatttta cgccagatac tagtttttct gtctcaaaaa ctgcagatgg
     2641 agaacaattg aaaaaagaca tattagtaag agaagccggg gaaaacctat ttttggcagt
     2701 gaagataact ggattattca aaaatatgca catccgtatc atgccgaagc aagaaaaacc
     2761 ttacagaaga ctagcaaaaa tttcagagtc tcaaccagaa ttccaacaaa gcaatgtcca
     2821 aggaacatta gtcgggttct ttacgcctga attattccaa ggagttgctg cagcgggatt
     2881 tcacttgcat tttatcgatg atacacatac atttggcgga catgtaatgg attttgaagt
     2941 ggctgaagga aaagttgaga ttagccgcat ctcgtccctt gtacagcatt ttccagttga
     3001 tgatccgact tttgttcacg aaacgattga ttatgctgat ttagcagcag aaatccaaca
     3061 agcagaatag aaaaagacag cgagatgcgt tcaaggtgat taacctgacg tatctcgttt
     3121 ttttgaggag gaaacctagc gtttacaaaa aaactgagct ataatcttct ccatagatca
     3181 aaaaggagcg gtttttatca tgtggacaga aaaacagaaa aaagatgcat acgaaatttt
     3241 attattacag caacaaggat tattagaagc agaagataac tggttagcaa atttagcaaa
     3301 ttcatctgca ttgttgaatg agactttgcc tgagactgtc tttgcaggat attatttatt
     3361 cgatggtaat gaattgattt taggaccgtt ccaagggcga gtttcttgca cacgtatcaa
     3421 gatgggaaaa ggagtttgtg gagaatcagc tgaaaaacaa gaaacattga tcgttgatga
     3481 tgtcaaaacc catgcaaatt acatttcctg cgattcagcc gcacaatcag aaatcgtagt
     3541 gccaatggta aaagaaggta atttaatcgg tgttttagat atcgattgcg gagtaacgaa
     3601 agggtatgat gaaatcgatc aagcatttct agaaaaatat gtagatcttt tattagcaaa
     3661 ttttaatata aatgcttttt catttattaa taactaaaat cgtctattga aacaaaaaag
     3721 aagagaaatc aagaa
//
LOCUS       DAFBVQ010000129         3655 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.135, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000129 DAFBVQ010000000
VERSION     DAFBVQ010000129.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3655)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3655)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3655
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.135"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            116..976
                     /locus_tag="LLC22_002812"
     CDS             116..976
                     /locus_tag="LLC22_002812"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002384409.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2520 domain-containing protein"
                     /protein_id="HBK5436008.1"
                     /translation="MEVIIMNVGFIGAGKVGCSFGKYFQEHKIQVTGFYSKSEDSSLA
                     ASNFTSSKQYLNLRELVDENDTIFITTPDGQIQEVWQEIKNYQIKNKLICHCSGAISS
                     DIFSNIQDYGAYGYSVHPMFSISDKYNSYKKLKKSFITIEGDEKYAKFLCDFFKKLGN
                     STVIVSKENKSLYHAASVVSSNLVLGLINTSVTYLIQCGFTEKMAIEALYPLIEFNIR
                     NIKEKGIIESLTGPVERCDISTIKGHCEVLSDEDRALYMLLSKNVLEIAMLKNINRDY
                     SELEKYLGES"
     gene            988..1815
                     /gene="panB"
                     /locus_tag="LLC22_002813"
     CDS             988..1815
                     /gene="panB"
                     /locus_tag="LLC22_002813"
                     /EC_number="2.1.2.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="3-methyl-2-oxobutanoate
                     hydroxymethyltransferase"
                     /protein_id="HBK5436009.1"
                     /translation="MKNTAVTFKESKLRNEKLTMLTAYDYSTAKIIDEAGINGILVGD
                     SLGMVCLGHEDTLSVTMEDMIHHTRAVTRGAKNTLVVADMPFMSYQTSVYDSVVNAGR
                     LIKEGRAQVVKLEGGIEVCDKIEAIVKASIPVMAHIGLTPQSVNAFGGFKVQGKDKEA
                     AKELIRAAKAVEKAGAFAVVLECVPTKLAELISKEISIPTIGIGAGAGCDGQILVYQD
                     MLGMYSDFTPKFVKKYANLSEEMNKAFTKYIEEVKDGVFPGPEHGFKISDDVLEKLY"
     gene            1830..2678
                     /locus_tag="LLC22_002814"
     CDS             1830..2678
                     /locus_tag="LLC22_002814"
                     /EC_number="6.3.2.1"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369228.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pantoate--beta-alanine ligase"
                     /protein_id="HBK5436010.1"
                     /translation="MVIFKTVNDVRSQVKEWKKQGLKVGLVPTMGYLHEGHESLIRKA
                     SKENDKVVVSIFVNPTQFGKNEDLGSYPRDLERDIEVCTRGRATAIFNPEVEEMYCDN
                     ASTFVNITGLTEGLCGASRPIHFRGVCTVVSKLFNIIPADRAYFGEKDAQQLAVIKRM
                     VRDLNIDIDVVGCPIIREEDGLAKSSRNTYLSLEERSSATILNKSLTLAKEALNNGER
                     DSLKIIEIISKNINTYNLAKIDYVEVVDSLSLQRVNYIEKSVLVAIAVFIGKTRLIDN
                     FTFELQ"
     gene            2688..3083
                     /locus_tag="LLC22_002815"
     CDS             2688..3083
                     /locus_tag="LLC22_002815"
                     /EC_number="4.1.1.11"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aspartate 1-decarboxylase"
                     /protein_id="HBK5436011.1"
                     /translation="MKVTMLKGKIHRATVEQAELDYVGSITVDMNLLEAAGIYEYEKV
                     QIVDVNNGNRFETYTIAGERGTGMICLNGAAARCVSTGDKIILMAYCELNENEVKDHR
                     PKVVFVDDNNKVERVTSYEKHGRLSDIIL"
     gene            3285..3655
                     /locus_tag="LLC22_002816"
                     /pseudo
     CDS             3285..3655
                     /locus_tag="LLC22_002816"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="frameshifted; incomplete; missing C-terminus;
                     Derived by automated computational analysis using gene
                     prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT         1425 a          412 c          722 g         1096 t
ORIGIN      
        1 gatattatga taaattaact atggatgata tttgaaaaaa acatactgta tatttgattt
       61 aatttttatt tttaagctca tatcgtaaga atgggacttg tagtctcact tctttatgga
      121 ggtgataatt atgaacgttg gttttattgg agccggcaag gtaggttgtt cattcgggaa
      181 gtatttccag gaacataaaa tacaagtaac aggattttat agtaaaagcg aagactcgtc
      241 attagcagct tcgaatttta catctagtaa acaatattta aacttaagag aattagtaga
      301 tgaaaatgat actattttca ttacgactcc tgatggtcaa attcaggagg tatggcaaga
      361 aattaaaaat tatcaaatca aaaacaaatt aatctgccat tgcagtggtg caatatcttc
      421 agatatcttt tcaaatatac aggactatgg tgcttatggc tattctgtcc atcctatgtt
      481 ttcaatatca gataaatata attcatacaa aaaattaaaa aaatctttta taacaattga
      541 aggcgatgaa aaatatgcaa agtttttatg tgatttcttc aaaaagttag gtaatagtac
      601 tgtaattgta tctaaggaga ataaatctct ttatcatgcc gcatcagtag tatctagtaa
      661 ccttgtgcta ggacttatta atacaagcgt tacatatcta attcaatgtg gatttactga
      721 aaaaatggca attgaagctt tatatccatt aattgaattt aatattagaa atataaaaga
      781 aaaaggaatt atagaaagtt tgacagggcc agttgaacgt tgtgatattt caacaattaa
      841 aggtcactgt gaagttttat cagatgaaga cagagcttta tatatgctat tatcaaaaaa
      901 tgtattagag atagctatgt taaaaaatat taatagagat tatagtgaat tagaaaagta
      961 tttaggagag agttaggaga gaaatagatg aaaaatacag cagttacatt taaagaatct
     1021 aaattaagaa atgaaaaatt aacaatgctt acagcttatg actattcaac agcaaaaata
     1081 attgatgaag ctgggataaa tggaatatta gtaggagatt ctcttggtat ggtatgtcta
     1141 ggacatgaag atacactttc agtaacaatg gaagacatga ttcatcatac tagagcagtt
     1201 acaagaggag ctaagaacac tttagttgtt gcagatatgc catttatgtc ttatcaaact
     1261 tcagtatatg attcagtagt taatgcagga agattaataa aagaaggacg agctcaggtt
     1321 gttaaattag aaggagggat agaagtatgc gataaaatag aggctatagt aaaggcttct
     1381 atacctgtta tggcgcatat aggtttaaca cctcaatctg ttaatgcatt tggaggattt
     1441 aaggtacaag gaaaggacaa ggaagctgct aaagaattaa taagagctgc taaagctgta
     1501 gaaaaagcag gagcattcgc tgtagtgtta gaatgtgttc caactaagct tgcagagtta
     1561 atttctaaag agatatcaat acctacaatt ggtattggag caggtgcagg gtgtgatgga
     1621 caaattcttg tatatcaaga tatgttgggg atgtatagtg attttacccc taaatttgtg
     1681 aagaaatatg ctaatttatc agaagagatg aataaagcat ttacaaaata tatagaggaa
     1741 gtaaaagatg gagtttttcc aggtccagaa catgggttta aaataagtga tgatgtttta
     1801 gaaaaattat attaaaaggg tcaagaaata tggttatatt taaaacagtg aatgatgtta
     1861 gaagtcaagt aaaagagtgg aaaaaacaag gcttaaaggt aggattagtt cctactatgg
     1921 gatatttaca tgaaggtcat gaaagtttaa ttagaaaagc atcaaaagaa aatgataaag
     1981 ttgttgtaag tatctttgta aatccaactc agtttgggaa aaatgaagat ttaggtagtt
     2041 atccaagaga cttagaaaga gatatagaag tatgcacaag aggtagagca acagcaatat
     2101 ttaatcctga agttgaagag atgtattgtg acaatgcaag tacttttgtt aatataactg
     2161 gattaacaga aggtttatgt ggagctagta ggccaataca ttttagaggg gtttgcactg
     2221 ttgtaagtaa attatttaac ataataccag cagatagagc ttattttgga gaaaaggatg
     2281 cacaacagtt agctgtaatt aaaagaatgg ttagggacct taatattgat atagacgttg
     2341 tagggtgtcc aattataagg gaagaggatg gactagctaa aagttctaga aacacatact
     2401 taagtttaga ggaaagatct tcagctacta ttttaaataa atctttaact ttagctaagg
     2461 aagctttaaa taatggagag agagacagct taaaaataat tgagataata agtaaaaata
     2521 taaatactta taatttggca aagattgatt atgtagaagt tgttgattct ttatcattac
     2581 aaagagtaaa ttatattgaa aaatcagttt tagttgcaat agcagtattt ataggaaaaa
     2641 caagattaat agataatttt acatttgaat tacaataggg ggctataatg aaagttacaa
     2701 tgttaaaagg aaaaatacat agagctacag ttgaacaagc tgagttagat tatgtaggaa
     2761 gtattactgt tgatatgaat ttattagaag cagcaggaat atatgaatat gaaaaagtac
     2821 aaatagttga tgttaataat ggaaatagat ttgaaactta tacaatagct ggagagagag
     2881 gaacagggat gatttgcttg aatggagctg cagctagatg tgtatcaact ggagataaaa
     2941 taattttaat ggcatattgt gaattaaatg aaaatgaggt taaggatcat agacctaagg
     3001 ttgtttttgt cgatgataat aataaagttg aaagagtaac atcatatgaa aaacatggaa
     3061 ggttatcaga tataattctt taggttttgt aatgttattt atatatagct agactattat
     3121 tgaaatattt attgattact aattggatag atgtcaataa agtagacaca aaaagagaag
     3181 atacagactg tagacaaagt ccattttatg tgaatcggct acactagact agacagaaaa
     3241 aataaggtgt gtagaataat aaaaaacaca ctggaggatt tttcatgtca agacgtcaac
     3301 gaagaaccta ttcaaaagaa ttcaaacaac aaatcgtcaa tctctatctc gctggtaagc
     3361 ctcgcgcaga aattattcga gagtatgagc ttacgccttc ttctttcgat aaatggatga
     3421 agcaagcaca atcaacgggc tcattcaaaa aaagagacaa cttaacacca gaacaagcag
     3481 aattgatcgc actaagaaag aaaaataagc aactcgaaat ggagaatgat attttaaagc
     3541 aagcggcgct gatattcgga cgaaaagaca agtaattgat gccaacaagc ataaatattc
     3601 catatcagcg atgtgcaaaa ttctaaatat ttctcgtcag acctactatt atcaa
//
LOCUS       DAFBVQ010000130         3543 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.136, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000130 DAFBVQ010000000
VERSION     DAFBVQ010000130.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3543)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3543)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3543
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.136"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(560..1600)
                     /locus_tag="LLC22_002817"
     CDS             complement(560..1600)
                     /locus_tag="LLC22_002817"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343466.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiator protein A"
                     /protein_id="HBK5436012.1"
                     /translation="MNDFNYYKSKEIYREKYYQMPKVFFTNEKYMDLSNDAKIAYMLL
                     KDRFDYSVKNNWVDSDDNIFFIFTVEELMKLLQCREGKVSKIKKELEKAGLLKQKRGR
                     VNKRDGKIESMPNLLYLGKPEVTNQDVFKIMEEEDNTDTTVIAKIANTAKPREINDTT
                     VIAKIANTAKSSHIKDSTVIAKIADNLFYSNSIDTNRHIIDTETDQLQNQVLLDNFVD
                     IMKEDSINTFVPENVLNLIKTFSSTYEDAQKTVQTIHNAKKKAEELEQTVVVYEELES
                     YGIDADKGLYMTLLKAYQKQKTEKVNNLQNLIFVYVKNWFVEKAIAAKLANEQRETFN
                     ELPTVSTENWLE"
     gene            complement(1949..2275)
                     /locus_tag="LLC22_002818"
     CDS             complement(1949..2275)
                     /locus_tag="LLC22_002818"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299230.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436013.1"
                     /translation="MAEDNRSQAAVSRLLGNKNKKNFKSKEVEEIELTKKNISKVIKD
                     QGSSVRTADSIRINPILMSALKYWTTIAESDKSKPDVIEDALLKSIPEEYLIEGYKLA
                     KKQNKI"
     gene            complement(2262..3065)
                     /locus_tag="LLC22_002819"
     CDS             complement(2262..3065)
                     /locus_tag="LLC22_002819"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002311905.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ParA family protein"
                     /protein_id="HBK5436014.1"
                     /translation="MGDILMARILSVANQKGGVSKTTTSVNLAACLKFVYGKNVLLVD
                     IDPQGNATDNVGFDIDGTNQPTIYEVLKGEADITDAILDYKGIDVLPADIALSSAERE
                     FTQVGSEHRLKRVLQPIKDNYDYIIIDCPPSLGMLTVNAFTVSDEIIIPVEAAYFSLK
                     GLIKLSETIETVKEYTNDKLEVRGVLFTKYNKRYNISKEMTSAATEISRVIGAKIFKT
                     YIRRTITVDEAQAAGSDLINFNKPSTAEDDYKAFTEEYLKEVGDFDGRR"
BASE COUNT         1084 a          584 c          487 g         1388 t
ORIGIN      
        1 ccgttgcggg taataccgta acactgaagg gcacgcatta aggcgtcatc ttaatgcttt
       61 cctgtaggac actgacggag attaccagtc tcccgagcct tacaggggcc tttctttttt
      121 ttgtattttc aattatcaca atttatcgtc caaaagtgca gaacgaaaat caattcatca
      181 caagcatatc agacaattaa atttaaaaca actaaaaata tacaaaaaag tgtaattgaa
      241 tattagcagc actgcctgaa aagaagtaat atcaggcttt tcagcttggg gaaataagtg
      301 aattacctct cttcatgaat tattataact caaaaaagca catatgcaaa cactagttcc
      361 ctattttttt gaatgaaaaa taactaaaat atctaacgat tatgacttta aaacctacgt
      421 ttgtgattgt tttcataaac ttttaatcta aaaactccgg aataatagct atttatttgt
      481 aacatttgta ataaaattaa aatcataaaa aagttctaat ttaaaattga tcatttttat
      541 agtgatcgct ttttatcaac tactctagcc aattttccgt actaactgtt ggtaattcgt
      601 taaatgtttc tctttgttcg tttgcaagct ttgccgcaat agctttttcg acaaaccaat
      661 tttttacata aacgaaaatt agattctgca aattgtttac tttttcagtt ttttgttttt
      721 gataagcttt cagcaaagtc atatataatc ctttgtcagc atcaattcca taagattcca
      781 gttcttcata aacaacaact gtttgctcta attcttcagc ttttttcttt gcattatgaa
      841 tagtttggac ggttttttga gcgtcttcgt aagtactaga aaatgttttt atcaagttta
      901 atacattttc tggtacaaat gtatttatac tgtcctcttt catgatgtcg acgaagttat
      961 ctagtaaaac ttgattttgt aactgatcag tttcagtgtc tattatgtgt ctattagtgt
     1021 ctatagaatt agaatagaat agattgtctg cgattttcgc aattacggtt gagtccttga
     1081 tatgactgga ttttgccgta tttgcgattt tcgcaattac ggtggtatca ttgatttctc
     1141 gcggttttgc cgtatttgcg attttcgcaa ttacggtggt atcagtattg tcttcctctt
     1201 ccatgatttt aaagacgtct tgattcgtta cttctggctt gcctaagtac aataaattag
     1261 gcatggattc aatcttaccg tcacgtttat ttactcttcc tctcttctgt ttcagaagac
     1321 ctgctttttc taattccttt ttgattttag atactttacc ttcgcggcat tgtaacaatt
     1381 tcattaattc ttcaactgtg aatatgaaaa atatattatc atcagaatct acccagttat
     1441 ttttgactga ataatcaaat cgatctttaa gtagcatata agcaattttt gcatcatttg
     1501 atagatccat gtatttttcg ttagtaaaaa ataccttagg catttgataa tatttttcac
     1561 gataaatttc ttttgatttg taataattaa aatcattcat agccaatcct ctttctgtag
     1621 gatagcgttt tgttcaaaac tatgttacaa tgaattaaac aaatatatct atccactata
     1681 tatttttcta ctgctgataa gtcgccaaac tttgttaaag cagtagtctt tttttatctt
     1741 tttttagttt accttaaaaa ataaattaaa gcaaaccgct ctatttcaag gtttaagctc
     1801 atagtaacta tatcacgata ttacaataat attatatcac gatatcgtaa tattacaata
     1861 tgaagataag cgacttatca gctttgatac tactgatttt tataaaaaaa atatcacgat
     1921 attatgatat cgtgatattg aatgtaaatt aaattttatt ttgtttcttt gctagtttat
     1981 atccttcaat caagtattct tcaggtatgg actttaatag cgcatcttct ataacgtctg
     2041 gtttactttt gtctgattca gcaatagtcg tccaatattt gagtgctgac attagaattg
     2101 gatttatacg aatgctatct gctgttctta cactacttcc ttgatctttt atgactttac
     2161 ttatattttt cttggttaat tcgatttctt ctacttcttt tgatttaaaa ttctttttat
     2221 ttttatttcc tagtaatcta cttactgcag cttgactgcg attatcttct gccatcaaaa
     2281 tcaccaactt cttttaaata ttcttctgta aatgctttat agtcatcttc agctgttgag
     2341 ggtttattaa aattgattag atctgatcca gcagcttgcg cttcgtcaac ggttattgtc
     2401 ctacgaatat aagttttgaa aatttttgca ccaatgactc tagaaatttc ggttgctgca
     2461 gacgtcattt ctttagaaat gttataacgc ttattatact tagtaaatag aactcctcgt
     2521 acttcaagct tgtcgttcgt atattctttt accgtttcaa tagtttcact taactttatt
     2581 agtcctttta atgagaaata cgcagcttca actggaatga taatttcatc agaaacagta
     2641 aatgcgttga ctgtaagcat tcctaaactt ggtggacaat caattataat ataatcatag
     2701 ttgtccttga ttggttgaag tactctttta agcctgtgtt cacttcctac ttgagtaaat
     2761 tccctctctg cagaagaaag ggctatgtcg gctggcaaaa catcaattcc tttatagtcc
     2821 agaatagcat ctgtaatgtc agcctcccct tttaatactt cataaattgt aggttggttt
     2881 gttccatcta tatcgaaacc tacattatct gtagcatttc cctgaggatc aatgtccact
     2941 aaaagtacat ttttaccgta aacaaatttc aaacatgctg ctaaattaac gctagtcgta
     3001 gttttagaaa ctccaccttt ttgattggct actgacaata ttcttgccat taaaatatcc
     3061 cccattcatc ttatattata atataattat atcataatat tgtgatattg caatatcgta
     3121 tatgcattat attgtaatat tgtgtgatta ttttgtttta aagatatata tcggttcgga
     3181 tataaagatt attcatatgt tattcgaaat taaaataatc actttttatt actttaaaat
     3241 tttttattaa tgataagaaa tatgttttgc gagcagcaac tagaataatt taaacattac
     3301 taaactgtct atattgttac taataattcc cttcttatag tgcattttct tagaaaaaaa
     3361 caatattacg atatcatgat attaagatat cgtaatatta tacaattgtg attgatatta
     3421 tatatgtttt tttatttttt tatcatgttt aatcttgaag gaatcatatt ctttttctaa
     3481 agacaggagc ttttcataaa catcagacat gtttaaacta gaggccaggc ttaaatcata
     3541 aac
//
LOCUS       DAFBVQ010000131         3535 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.137, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000131 DAFBVQ010000000
VERSION     DAFBVQ010000131.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3535)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3535)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3535
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.137"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(185..742)
                     /locus_tag="LLC22_002820"
     CDS             complement(185..742)
                     /locus_tag="LLC22_002820"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294436.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436015.1"
                     /translation="MRNLSNRNKILIIIVVIAVFHLGTNAVLSRIILGPKPPRPEITR
                     GEFDFRLEYEVDGERIVIEDTIVALFDGFSADAGSMAWYRTWRLHLASDRRSRNILLD
                     ELEDGRRIYYVPESANYSMGDVQKKREPNPNWYPFNGVTIEYPRNKTPEIGAKFISGL
                     EDLYDRFGIRLISWEHDPPIENRFE"
     gene            complement(921..1532)
                     /locus_tag="LLC22_002821"
     CDS             complement(921..1532)
                     /locus_tag="LLC22_002821"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436016.1"
                     /translation="MNSNRGNKMEYNGSMRIVQIIFWITSGIVIIGGVFLMLPSLIFP
                     FFALISPKIPEPEITYGEFPFRIEYELDGQINIIEDTVIAEFNGCEFSAGSMKRERRW
                     RSRLASGREDLPFGDDLGIYFSRGSARYYMGENVQSMSLKPHIALRNLEEGFKREVDF
                     ILGESGYIRTVLNFGEAQEVLTQYGITLINWEISEPIVNNFGD"
     gene            complement(1645..1902)
                     /locus_tag="LLC22_002822"
     CDS             complement(1645..1902)
                     /locus_tag="LLC22_002822"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436017.1"
                     /translation="MRAVHVNPTIEITMIGHSKGGAEAANSVAINTNAIIFNPATVNL
                     SAYELDSNTYTANMVAYVVEGDALNVVFGGVYTYWRINHVR"
     gene            complement(2499..2777)
                     /locus_tag="LLC22_002823"
     CDS             complement(2499..2777)
                     /locus_tag="LLC22_002823"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287830.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436018.1"
                     /translation="MEKHNITGSMYVDDQWFISTDEVKIAAIRRDYLQKIHKIKDPNG
                     KKARLIITLITSNGKKLKLAGSYDNVKKFEHWYLQKDSISLNKQFEKN"
     gene            complement(2811..3062)
                     /locus_tag="LLC22_002824"
     CDS             complement(2811..3062)
                     /locus_tag="LLC22_002824"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436019.1"
                     /translation="MKEKPINKWSLYKNSMFGVVIFGVCAGLFLFILLQTVTLFSSNP
                     TYGWRDSIALGMFAGGYGFLLLFSILTLSPIHGLIQLWK"
BASE COUNT         1078 a          725 c          470 g         1262 t
ORIGIN      
        1 tatttgccac tttgattcgt ataaagctaa caactattaa ctcctctcag ctaatagttg
       61 ctctcttttt tattcagatt catttttgct gatcacagcc tagtatttca atggttttga
      121 acactaaacc aaattgttcc attacaacat tcactggctg atgaaatgga ttagtagatt
      181 tcgattattc aaagcgattt tctattggtg gatcgtgttc ccaactaata agacggattc
      241 caaacctatc gtacagatct tctaaaccac ttataaattt tgcacctatt tcaggtgttt
      301 tattgcgtgg atattctatt gttacgccat taaatggata ccaattagga ttaggctctc
      361 tttttttctg tacatctccc atagaatagt tagcactttc tgggacataa tatattcttc
      421 gaccatcctc taattcatct aataagatat ttcgtgatcg tctatcactt gctaaatgta
      481 gacgccacgt gcgataccat gccatgctac ctgcatctgc agaaaatcca tcaaataatg
      541 caacaattgt atcttctatc acaatccttt ccccatctac ttcatattct aatctaaaat
      601 caaactcccc tcgggtaatt tctggtcttg gtggcttagg acccaatatt attctactta
      661 aaaccgcatt cgttcccaga tgaaacacag ctataacaac aataatgatt aatattttgt
      721 ttctatttga taaatttctc attattcgca catcacctct acattctcac atattagttc
      781 gtaatactcc tttaatatca aaatatctac tggtcgtaat aatattcgct atgaattcct
      841 actactcgta taagaaaggc caaatcatca gcttttactt gctgatgatt tggcttgttt
      901 ctatttatcg taattgtttt ctaatcacca aaattgttaa caatcggttc agatatttcc
      961 cagttgatta aggtaattcc gtattgtgtc aaaacttctt gcgcttctcc gaaattaagt
     1021 acagttctta tgtatccact ttctcctaat ataaagtcta cctctctttt aaaaccttcc
     1081 tcgagatttc taagggctat atgtggtttt aatgacattg attgtacatt ttcccccata
     1141 taatatcgcg cacttcctcg actaaaatag attcctagat cgtccccaaa aggtagatct
     1201 tctctaccac tagctaatct acttctccat cttcgttctc ttttcataga acctgcgctg
     1261 aactcacacc cgttaaactc agctatgaca gtatcttcaa ttatgttaat ctgtccatct
     1321 agttcgtatt caatcctaaa tggaaattct ccataggtga tttccggttc gggtatttta
     1381 ggtgagatta atgcaaagaa aggaaatatt aagcttggca acatcaaaaa aactcctcct
     1441 atgatcacaa ttcccgatgt aatccaaaat ataatttgta caattctcat tgatccattg
     1501 tattccattt tattccccct attactattc atatccgcct atctatatcg atcttccaat
     1561 gcagagataa ttgcttccat accttgattt tttactgagt tacctatgcg agatatcatt
     1621 ctccactaag gtgcatcata ttgtctatct aacatgatta attctccaat aggtgtatac
     1681 tcctccaaaa acaacattta atgcatctcc ctcgacaaca taagctacca tgtttgctgt
     1741 atatgtgttt gagtctaatt cataagcaga taaatttact gtcgctggat taaatataat
     1801 cgcattcgta tttatagcta ctgaatttgc tgcttcagca ccaccttttg aatgtccgat
     1861 cattgtgatt tcaatagtag gatttacgtg gacagccctc accgtttacc ctgaccatta
     1921 tagaaatcgc ttactttttt gaactacgca acaaaggata caatgctcct aacttcactg
     1981 tctccatttt tgtccactaa ggaatataaa aaataggcat taattcattt aattcggtca
     2041 caacacgtta ccttttaaat cattatactg tatctcatac attattatca ataaactatt
     2101 ataaaaatgc aaaaaatgct ttatcaatct attttgtaat tggtcataat atcattgaaa
     2161 tcataccctg tatcgatttt tcctatgaat ctcgtctatt tgtgattgac gaaaaagagg
     2221 caagacagac actggaatgg taattttacc cactattttg ctccaactat ttgtaatcgt
     2281 acccactttt gaaataccga gatgatcatt ttaattgata tgctgattcc caagcaaaac
     2341 cccaagaaat taaatgctct atcgcatcta gcttcttggg ttttgcttat ataaattcca
     2401 acatttaaat tttttatgct gttcggtctc agaaatgccg tttttgctta tatcacaata
     2461 tcaagatgtc aaattattcg tgttgccgat gactttgatt aatttttttc aaattgttta
     2521 ttaagactaa tgctgtcttt ttgcagatac caatgttcga actttttaac attatcatat
     2581 gatcctgcaa gttttaactt cttaccatta gatgttatca aagttataat taaccttgcc
     2641 tttttcccat taggatcttt tattttatga attttctgca ggtaatctct cctaatggca
     2701 gctattttta cctcatcagt gctgataaac cattgatcat ccacatacat actgcctgtt
     2761 atgttgtgtt tttccatttc ttccgagaac gaaaagttta aggctcgttc ttacttccaa
     2821 agttgaatga gtccatggat tggacttagt gtgagaattg agaacaacaa taagaatcca
     2881 tatcctcccg caaacatccc taaggctata ctgtctctcc atccataagt aggattagaa
     2941 gagaaaagag tcaccgtttg taataatatg aaaaggaata atccagcaca aacaccaaag
     3001 ataacaactc caaacattga atttttatac aatgaccatt tatttatagg cttttctttc
     3061 attttacttc cccctactgt tctgttcaca cggaatgaat tcaaagttca taagccctcc
     3121 tctttgaaca tatgaatacg acttgctaac tatactttaa aaaagcttgt tttaagcggt
     3181 tataggcgag ttgtaatctc tattcatctc attagcaaat aacttgccga aaagtctact
     3241 gaaattaaag cagatagtgg aagaattatt tagccaggat agacactatt tgtgaaacac
     3301 atgtctttac ttttgaaatt ctatgatgaa aagccttgga atacagtagc tcttaattgg
     3361 taatactttt tccattataa ataacctctt ttcattttat atttatcccc tctaaaaata
     3421 atatctaatc taatatttta aacttatatt tccctcgctg tgctaataga gcattactaa
     3481 ataaatagaa actagaaaaa agcattacgc ctgccagaat aaaccaatta tttgt
//
LOCUS       DAFBVQ010000132         3294 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.138, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000132 DAFBVQ010000000
VERSION     DAFBVQ010000132.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.138"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            39..590
                     /locus_tag="LLC22_002825"
     CDS             39..590
                     /locus_tag="LLC22_002825"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303113.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF334 domain-containing protein"
                     /protein_id="HBK5436020.1"
                     /translation="MKRLEASTSNFNNKLDVFEEKTKHARLNFETTAKHYIKRLDEDN
                     LKLDFQQAIQDELSDTKDEIREVTKQAREETKEYKEILESKIKDHNKVVDKSNTALKV
                     MTKGVTNIFFVLIIFVLVMLVTGPIGHFFGIEHLYSFINGFIDDHESAWRYLMLILYA
                     VPYVFFAIILWLIALFFRVFNDL"
     gene            1266..1520
                     /locus_tag="LLC22_002826"
                     /pseudo
     CDS             1266..1520
                     /locus_tag="LLC22_002826"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002405927.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation protein"
     gene            1590..2102
                     /locus_tag="LLC22_002827"
     CDS             1590..2102
                     /locus_tag="LLC22_002827"
                     /inference="COORDINATES: protein motif:HMM:NF013677.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5436021.1"
                     /translation="MTNKNNERYSTELKATAIKKMMPPENRGIRQLSQTLGIPEATLC
                     SWRKKARIQGNTTPGTKKNVEKWSSEDKFLIVMESFSMNQVELAEYCRKKGLFKEQIE
                     AWKKTCLSANEQEENRTRELATELKEEKKQARQLEKELRHKEKALAEAAALLLLRKKA
                     HAIWGDQEEE"
     gene            2099..3136
                     /locus_tag="LLC22_002828"
     CDS             2099..3136
                     /locus_tag="LLC22_002828"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBK5436022.1"
                     /translation="MISSSDRKQAVELIQEANRNGARLTYACNELNISVRTYERWTRE
                     GTIAHDQRPLAKRPVPKNKLTDQEREKIIETVSKKEFMNLPPSQIVPKLADCSIYIAS
                     ESSFYRVLREKNMQHHRGRSQVSQKRIPPSHLATKPNEVWTWDITWLKGPIKGLFYRL
                     YLIIDLFSRKMVGWEIWESEEARHAEKLIKQTVLKERIQGQPLVLHSDNGSPMKAATF
                     QVLLEKLGIQSSYSRPRVSNDNPYSEAAFRTLKYRPEYPNNGFKTIDDARKWTKEFVD
                     WYNDSHLHSGIQFVSPAACHEGRHLAILEKRKQVYEDAKKRHPERWSKGVRNWTPHQS
                     VALNPLKETES"
BASE COUNT         1214 a          555 c          654 g          871 t
ORIGIN      
        1 agagcgagca agacaggaac gagagaacaa acatactcat gaaaagacta gaggcttcga
       61 cctcgaactt taataataag ttagatgttt ttgaagaaaa gactaagcat gcaagattaa
      121 actttgaaac aactgcaaag cactatatta aacgacttga tgaagataat ttgaaattag
      181 attttcaaca agctattcaa gatgaattaa gcgatactaa agacgaaata cgtgaagtga
      241 cgaaacaagc gagagaagaa acaaaagagt ataaagaaat cttagaaagt aaaataaaag
      301 accataacaa agtggttgat aaatcgaata cagcgctaaa agtgatgaca aaaggcgtta
      361 caaatatatt ttttgtgcta attatttttg tacttgtaat gcttgtgaca ggtccgatag
      421 gtcatttctt tggtattgaa catttatata gctttattaa tggttttatt gatgaccacg
      481 aaagtgcatg gcgatatttg atgttgatac tttatgcagt accctatgta ttcttcgcta
      541 tcattctgtg gctcatagca ttgtttttta gagtatttaa tgacctttag gtagatttat
      601 atataaaaag ggctaaatac gcaaaatacc cccttaaaat gcaaaataaa tgcaaataag
      661 ggggtaactc cttatgaaaa aacaactaat agtattataa cacgttttta tgccgagaaa
      721 acttattggt tggaatgggc tatgtgttag ctaacttgtt agcgagttgg ttggacttga
      781 attgggatta atcccaagaa agtaccaact caacaacaca taaagccctg taggttccga
      841 ccaataagga aattggaata aagcaacgaa aggagttgag taaaatgagt gagaaaacga
      901 agaaaatcat tcgagtatca ttagcttttt cacaagtagt agtgcaatca ttgatagttt
      961 attatactta ccagcaatat aaattatcta aagagaatta agttttgatt atgtaataag
     1021 ttttggtact aaaaaagact tgatctaatt agaccaagtc ttttgttagt gttatattaa
     1081 taacaaaata aaaataagaa gtcgctcact ccccgaccaa agtttgtgag caaaataaac
     1141 agtcgatgtt tgtttcttaa ttgtatatct tgatattaaa cgatttaaga ttattcttca
     1201 agatatatat tcgcaaatgt aattggaaaa gcgacttctt aaacaaaatt aaggagtcgc
     1261 tttttatggc aaaaataacg aaaaatgagc aagaaaattt ggtggaaaat tacacaaaaa
     1321 aaccggcgta ctctaatagc cggttagacg cacatttcgt gtgcacttct aatccgaaat
     1381 tgagctttga cgctatgacg atagtcggaa accttaataa aaacagcgct aaaaagctat
     1441 ccgattttat gagtttagat ccacaaatta gactttggga tatacttcaa acaaaattta
     1501 aagctaaagc actacaagac cccctatgtt aggctagttg tcgtatagga taataagtta
     1561 taataaagac tatacggagg atgattacca tgacaaataa aaacaatgaa cgttactcta
     1621 ccgaactgaa agcgacagcc atcaagaaaa tgatgccacc cgaaaatagg gggattcgcc
     1681 aattaagtca aactttgggc attccagaag cgactctttg ttcttggcgt aaaaaagcta
     1741 gaattcaagg gaatactaca cccggaacga aaaaaaatgt cgaaaaatgg tcaagtgaag
     1801 ataaattttt aattgtgatg gaatcattct caatgaacca agtagaactt gcggaatatt
     1861 gccgaaagaa gggcttattt aaagaacaaa ttgaggcttg gaagaaaacg tgcttatctg
     1921 cgaatgaaca ggaagaaaat cgaacgagag aacttgcaac tgaactaaaa gaagagaaaa
     1981 aacaagcgcg tcaattagag aaagaattac gtcataagga aaaagcatta gcggaagccg
     2041 ctgctctctt attactaaga aaaaaagcac acgcgatttg gggggaccaa gaggaagaat
     2101 gatttcatct tcagatcgca aacaagctgt tgaacttatt caagaagcca atcgcaatgg
     2161 ggcccgtctc acctatgcct gtaatgagct gaatattagc gttcgaacct acgaacgatg
     2221 gacgcgtgaa ggtacgatag cgcatgatca acgccctttg gcgaaacgtc ctgtacccaa
     2281 aaataaactg acggatcaag aacgcgaaaa aataatagaa accgtttcaa aaaaagaatt
     2341 tatgaatttg ccacctagcc aaattgtacc aaaacttgcg gattgctcga tttatattgc
     2401 atcagagtct agcttctatc gtgtattgcg agaaaaaaat atgcaacatc accgtggccg
     2461 aagtcaagtt tcacaaaaac gcataccgcc aagtcacctt gcgacgaagc caaatgaagt
     2521 ttggacttgg gatattactt ggctaaaagg tccaataaaa ggactctttt accggttata
     2581 tctcatcatt gatttattta gccgtaaaat ggtaggctgg gagatttggg aatcagaaga
     2641 agctcgtcat gccgaaaaac ttattaaaca gacggtgctt aaggaacgta tccaaggaca
     2701 gccgttggtt ttacactccg ataatggcag ccctatgaaa gccgcgactt ttcaagtctt
     2761 actcgaaaaa ttaggaattc aaagttctta ttcaagacca cgagtgagta atgacaatcc
     2821 ttattcggaa gcggctttcc gaacgttaaa atatcgacca gaatatccca ataacggctt
     2881 taaaacaata gatgatgctc gaaaatggac gaaagagttt gtcgattggt ataacgattc
     2941 tcatttgcat agtgggattc aatttgtgtc tcctgcagcg tgtcatgaag gacgacatct
     3001 cgctatttta gagaaacgaa agcaggttta cgaggacgct aaaaagcgcc atcctgaacg
     3061 ctggtcaaaa ggtgttcgaa attggactcc acatcaatcg gtggcgttga atcctttaaa
     3121 agaaacagaa agttaacagg agcataatct ttcaagatta tcaaataacc ctcgtcaccc
     3181 aataggggaa aaagttattc ttcccctatt ggataacgag gccaaccgac catagggagg
     3241 ttctgctttt tgataggtgg aaaataaaaa tacgacaact atattgacaa acac
//
LOCUS       DAFBVQ010000133         3272 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.139, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000133 DAFBVQ010000000
VERSION     DAFBVQ010000133.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3272)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3272)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3272
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.139"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(368..1486)
                     /locus_tag="LLC22_002829"
     CDS             complement(368..1486)
                     /locus_tag="LLC22_002829"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016631402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436023.1"
                     /translation="MAKKDKELLTQLTSEGAKGPFVTIMLNTHVAHQDVEKDQIKFKN
                     FAKEAKKRFEKKYSEHDWSPFQEKIENLLGDPSFWRSATTSVAVIITADQTYIHRLSI
                     PVDDQYYVSDLPYLLAIIKNGQFNYSYYLLGLNRDSMKLYEVSNKQVKEVSLPEGAPV
                     DVVTALGSELTGGGLNFSSNGGGGARDGVTFHGVNPKDEEVEIDWVNYYQAVDTYLKD
                     SFENPEQWPIYLFALPENQTMFKKIAKNPYYCADVAISASPAQLSFRDIEEGAKKLSS
                     ELAAQESKEYNKLLDKKFIDQLVDIVPAAKEGKVSHLFIATSNLADGFGEDPETEYDR
                     RQVLNALADDVIINGGKVFILDQKDAPDEKSLTAILRY"
     gene            1957..3264
                     /locus_tag="LLC22_002830"
     CDS             1957..3264
                     /locus_tag="LLC22_002830"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302201.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="D-alanyl-D-alanine carboxypeptidase"
                     /protein_id="HBK5436024.1"
                     /translation="MSIKKTRLVLLLASLILCLASFLPAVAVQAEDTFKVNAKAAFAV
                     DAQSGKILYDQDGEKTMGIASITKIIGLYIVLDQVKEGKLSWGDKVSISDYAENLSIT
                     PDLSNVPLHKENTYTVKELFDSAIIQSANASMVALAEKISGSEAKFTERMKEQLKDWG
                     IKDATIVNASGLNNSYLGENRPEGTGENDENQMSAQDVAIVARHLILDFPEILDVSST
                     TTQMFGENTQSPVEMVNWNWMLPGFVNYKEGVDGLKTGTTELAGACFVGTITKNDQRI
                     ITVVLNADGHAENPSARFNETDRLMDYCYDNWSEKELGKANASIPSLKTIDVKDGKES
                     TVPVVLKSPVKVWVRNDMDTGKLTITPTLDKKQVTDNEIQAPMDKGTKIGTATITLAD
                     DKLGYLEDNNAPSTEIITDKTVEKANIFVIGWRRVAEFFGNLF"
BASE COUNT         1025 a          679 c          589 g          979 t
ORIGIN      
        1 tttttaaacg gtgttccaga agtagcttct tcggaaataa gccgaaattt cacaaaaatt
       61 tgagaaataa tttttgtcaa tctcttctta tttcttgaag ctgaccactt ctgtcacaac
      121 ctcttcctta aacggtgttc aaaagcttgc atctgcggta ataagcccac caaacaaaaa
      181 atatgaagag ctatttttgc ttgctgttct tattacttga tgcagaacag ctttttcaca
      241 acctctcata cacggtgttt aatcagctga ccttcggtat tagctcaaaa aacggaaaaa
      301 tatgtgaaac tatttttccg tttgtttctc taatactcag gtcaaaacac tgatttcaca
      361 acctctttta ataacgaaga atcgctgtca gactcttttc atctggcgca tctttttgat
      421 ccaaaataaa cactttcccg ccattaatga tcacatcatc tgctaatgca ttcaacactt
      481 gacgccgatc atattctgtt tcaggatctt caccgaaacc atcagctaag tttgacgtag
      541 cgataaataa atgtgacact tttccttctt tcgcagctgg aacgatatca actaactgat
      601 cgatgaattt cttatctaag agtttattgt attcttttga ttcttgagct gcgagttcac
      661 ttgacagctt cttcgcccct tcttcgatat ctctaaagga tagctgcgca ggagaagcag
      721 aaatcgcaac gtctgcacaa taatagggat ttttagcaat ttttttgaac atcgtctgat
      781 tttctggtaa tgcaaataaa taaatcggcc attgttcagg attttcgaaa gaatccttca
      841 agtacgtatc aacagcttgg taatagttga cccaatcgat ctctacttct tcatcttttg
      901 gatttacgcc atggaaagtt actccatctc gggctccgcc tcctccatta gaagagaagt
      961 tcaaaccgcc acctgtcagt tcagatccca atgcagtaac gacatcaacc ggtgcccctt
     1021 ctggtagaga tacttctttt acttgtttgt tgctgacctc atacaatttc atggagtcgc
     1081 ggttcaatcc caataaataa taagaatagt tgaactgccc atttttgata atagccagta
     1141 aataaggaag atcacttaca tagtattgat cgtctaccgg gatactcaaa cgatggatat
     1201 aggtctggtc agcagttata atgaccgcta cactcgtagt tgcactacgc caaaacgaag
     1261 gatctcctaa caaattttca attttttctt ggaacgggga ccagtcatgt tcggaatatt
     1321 ttttctcaaa acgtttcttt gcttctttcg caaaattttt gaatttgatc tgatcttttt
     1381 ccacatcttg atgggcgaca tgcgtattca gcatgatcgt gacgaatggt cctttagcgc
     1441 cttctgaagt caattgtgtc aataattctt tatccttttt tgccataaac gtacccctcc
     1501 taaaaaaatc attcctttgt ttctatctaa agtctaccac aacactattt ttccatacaa
     1561 taaaacgtat ctaaaaaaat aaaacggttt ctacggtttt aaatttagct atttttttaa
     1621 gttatcttca taatttcctc aattatttag ccccagtctt caactattct tcatgaaatg
     1681 ctgataaact aagaaaaaga ataaaagagg tggatcttat gcatttgatt atgattttca
     1741 gtttattaag tattatcagt ttatttgctt tcagcgcttc ccgcttatta gatgcggaaa
     1801 cacagcctat tcctgtaaaa gtacgtaaaa acgaccgcta aacttccata acgcgcgttc
     1861 ttatcctaaa gttttttcag aaacattgaa actctctccc ctctctgata aaattttaat
     1921 ttgtagcgaa acaaattaat tacaaggaga tcggatatgt ccataaaaaa aacacgtcta
     1981 gtcctattat tggctagtct cattctttgc cttgcttctt ttctaccagc tgttgctgtg
     2041 caagctgaag atacgttcaa agtaaatgca aaagcagctt ttgctgtaga tgcgcaaagc
     2101 ggtaagattc tttatgatca agatggagaa aaaaccatgg ggatcgcttc aatcacaaaa
     2161 atcatcggtc tttacatcgt ccttgatcaa gtaaaagaag gaaaactgtc atggggtgat
     2221 aaagtttcga tttcagatta tgcagaaaat ttgagtatca ccccagattt atcgaatgtt
     2281 cctttgcata aagaaaacac ctacactgtc aaagaattat tcgactctgc aatcatccag
     2341 tcagccaatg cttcaatggt ggccttggca gaaaaaatct ctggcagcga agctaaattc
     2401 actgaacgaa tgaaagaaca attgaaagat tggggaatca aagatgcaac aatcgttaat
     2461 gcatcaggat tgaacaactc ttatcttggc gaaaaccgac cagaaggcac tggagaaaac
     2521 gacgaaaatc aaatgtctgc tcaagatgtg gccatcgttg cccgccattt gatcttggat
     2581 ttcccagaaa tactggatgt atcaagtact acgacccaaa tgtttggcga aaatacgcaa
     2641 tcaccagtgg aaatggtcaa ctggaactgg atgctcccag gattcgttaa ttacaaggaa
     2701 ggcgtggacg gattaaaaac tggtacgact gagcttgcag gtgcttgttt cgttggtacg
     2761 atcactaaaa acgatcaacg gatcatcact gtcgtattga atgcggacgg ccatgcggaa
     2821 aacccgagtg cccgcttcaa tgaaacagac cgtttgatgg actactgcta tgacaattgg
     2881 tcagaaaaag agctcggaaa agctaacgca agtattccta gtctaaaaac cattgatgta
     2941 aaagacggaa aagaatcaac agttcctgtt gtgcttaaaa gccctgtaaa agtatgggta
     3001 cgaaacgata tggatactgg caaattaacg atcacgccaa cacttgacaa gaagcaagtc
     3061 actgacaatg agatccaagc acctatggat aaaggtacaa aaatcggtac cgctacgatc
     3121 accttggcag acgataaatt aggctattta gaagacaaca atgcaccatc aacagagatc
     3181 attacggata aaacagtgga aaaagcgaat atattcgtga ttggctggcg acgcgtcgca
     3241 gaatttttcg gcaacttgtt ttaattgaac aa
//
LOCUS       DAFBVQ010000134         3252 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.140, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000134 DAFBVQ010000000
VERSION     DAFBVQ010000134.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3252)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3252)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3252
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.140"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            3..587
                     /locus_tag="LLC22_002831"
     CDS             3..587
                     /locus_tag="LLC22_002831"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005876718.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidylprolyl isomerase"
                     /protein_id="HBK5436025.1"
                     /translation="MAFPQLDLKSEKGPKAVIKTNRGDITVQLFPELAPKTVQNFIEL
                     SKKGYYDGVIFHRVIPDFMIQGGDPTGTGMGGESIYGESFEDEFSRELFNLRGALSMA
                     NSGPNTNGSQFFIVNNTNVPANMLGQLEGAGFPSEIIEAYKGGGTPWLDFRHTVFGHV
                     LEGMDTVDEIANVQRGPQDRPVHDVVIETIEISE"
     gene            complement(664..1857)
                     /locus_tag="LLC22_002832"
     CDS             complement(664..1857)
                     /locus_tag="LLC22_002832"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629534.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyridoxal phosphate-dependent aminotransferase"
                     /protein_id="HBK5436026.1"
                     /translation="MTGGLKMIEFDKQISRKDTESVKWDAIAETYQMDDLLPLWVADM
                     DFLSPGGVAKAFSEYIKHGIFGYATLSDKLYQAIIHWERQHHAVELTKENIVFTSGVL
                     TSLAAAVQTFTKPGDSILIHDPVYPPFSSIIETNQRHIVRSSLLEKNNHFIMDLSDME
                     KKIEENNVKAMILCNPHNPGGRVWSKEELKQLSELCLKHQVILFSDEIHQDLTLFDHT
                     FTSMLTIDPNLDDLLVAFTSATKTFNLAAIKNSMVFIKNPEMKADFEKHLVMNQQHEI
                     NTFGLIGTQAAYETGGEWLSQLIPYLEKNVQTVNQFFEQYLPKVRIMNPEGTYLMWLD
                     FTAYISDDQELENTLVRKGKVVLNPGITFGPSGHGHMRLNIACPEETLLEGLNRIKYA
                     LETID"
     gene            1921..2301
                     /locus_tag="LLC22_002833"
     CDS             1921..2301
                     /locus_tag="LLC22_002833"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335490.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S1 RNA-binding domain-containing protein"
                     /protein_id="HBK5436027.1"
                     /translation="MTYKIGQIIEGKVTGIQPYGAFVSLDNETQGLIHVSEVQSGYTK
                     NIHSLLKVGQPVTVQIIDIDEYSKKISLSLRTLEKTNPAVPYRRKRYFTNKNRKIGFT
                     TIAEQLPIWIEEALSELERKENKK"
     gene            2375..2737
                     /locus_tag="LLC22_002834"
     CDS             2375..2737
                     /locus_tag="LLC22_002834"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014387120.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436028.1"
                     /translation="MASKRVAGTIMLHLEDGTKKFLVHSIDDKLEFALAELSEGKTGL
                     ANILNFLKEIVHIDVSKISLMELTNTHIKEENVPLFVFETEQKNQREELGEGYIWEEP
                     GQMRSVLGTYEVEGVPFF"
BASE COUNT         1102 a          528 c          615 g         1007 t
ORIGIN      
        1 atatggcatt cccacaacta gatttaaaaa gtgaaaaagg accaaaagct gttatcaaaa
       61 caaaccgtgg tgacattact gttcaattat tccctgaact agcaccgaag acggttcaaa
      121 atttcattga actttccaaa aaaggttatt atgatggcgt gatttttcac cgcgttattc
      181 ctgatttcat gatccaaggc ggcgatccaa ctggaacagg aatgggtggc gaaagtattt
      241 atggcgaaag ttttgaagat gaattcagtc gtgaactgtt caaccttcgc ggagctttat
      301 ctatggcaaa ttcaggtcca aacacaaacg gaagccaatt ctttattgta aataacacaa
      361 atgtgccagc taatatgctt ggacaactag aaggtgctgg attcccatca gaaatcattg
      421 aagcgtataa aggtggcgga actccttggc tagatttccg acatacagtc tttggacatg
      481 tactagaagg gatggacaca gtagatgaaa tcgcaaatgt acaacgtggt ccacaagacc
      541 gacctgtaca tgatgtagtg attgaaacaa ttgaaatttc agaatagttt ggtatggtac
      601 ggagtaatta tgaaaaagga cgaaacctag taaggtctcg tccttttatt ttgaataaat
      661 gatttaatcg attgtctcta aagcatactt gattcgatta agtccttcca gtaaagtttc
      721 ttctggacaa gcaatattca agcgcatatg cccatgaccg gaaggaccaa acgtgatgcc
      781 aggatttaat acgacttttc ctttccgaac aagagtgttc tccaattctt ggtcgtctga
      841 aatataggcg gtaaaatcta accacattaa gtaagttcct tcagggttca ttattctcac
      901 tttcggaaga tactgttcaa aaaactgatt aactgtttga acattttttt ctagataagg
      961 aatcagttgg cttaaccatt ctccacccgt ctcataagcc gcttgggttc caatcagtcc
     1021 aaaagtgttg atttcgtgct gttggttcat cactaaatgt ttttcaaaat cagctttcat
     1081 ctctggattt ttgataaata ccattgaatt tttgattgca gctagattga aagtcttggt
     1141 tgcggaagta aaagcaacta gtagatcatc taaattagga tcaatcgtta gcatggaagt
     1201 aaatgtatga tcgaataaag ttaaatcttg atggatctcg tcactaaaca gaatcacttg
     1261 atgttttaaa cacaattcgc ttaactgttt caattcttct ttgctccaaa cacgccctcc
     1321 aggattgtga ggattgcata aaatcattgc ttttacattg ttttcttcga tttttttctc
     1381 catgtcagac aagtccatga tgaaatgatt atttttttct agcaaagagc ttcgaacgat
     1441 gtgacgttga tttgtttcta taatagagga aaatggagga taaactgggt catgaatcaa
     1501 aatagaatcg cctggttttg taaaagtttg tactgctgca gctaaactgg ttaacacacc
     1561 acttgtaaaa acgatatttt ctttcgtcaa ctccacagca tggtgttggc gttcccaatg
     1621 aatgatagcc tgatatagtt tatcagacag agtggcataa ccaaagattc catgtttgat
     1681 gtattcacta aacgctttag ctaccccacc gggagacaag aagtccatat ctgctaccca
     1741 caaaggaagt aagtcatcca tttgatatgt ctcagcaatt gcgtcccatt ttacactttc
     1801 tgtatctttt cttgaaatct gtttatcaaa ttcgatcatc ttaagacctc cagtcatttt
     1861 cgtcgcttct ttttttgagc tatttacagt ataatgataa atgcgaagag agggaagtag
     1921 atgacttata aaattggaca aataattgaa ggaaaagtga cagggataca gccttatggc
     1981 gcattcgttt ctcttgataa cgagacgcaa ggacttattc atgtttcaga agtacaatcc
     2041 ggttatacga aaaatatcca ttcattgtta aaagtcggac agccagtaac agttcagatc
     2101 atcgacattg atgaatattc caaaaaaatc agtttatctt taagaacgtt agaaaaaaca
     2161 aatccagctg ttccatatcg cagaaaaagg tatttcacga ataaaaatcg taagatcgga
     2221 tttaccacta ttgcggagca gttacctatt tggatagaag aagcattatc tgaactagaa
     2281 cggaaagaaa ataagaaata aaaagtgtat tttttctgaa aatgtgctag aatttttatg
     2341 taagccatag aacaagttga tcgaggtgga aattttggca agcaaaagag ttgctggtac
     2401 aattatgttg catttggagg atggtactaa aaaatttttg gtccattcaa ttgatgacaa
     2461 gttggaattt gcgttagcgg aactttctga aggaaagact ggtttagcga atatacttaa
     2521 tttcttaaaa gaaatagttc atatcgatgt tagcaagatt agtttgatgg aattgacaaa
     2581 tacacatatt aaagaggaaa atgttccgtt gtttgtcttt gaaactgaac aaaagaatca
     2641 aagagaagaa ttaggcgaag gatatatttg ggaagaacca ggtcaaatgc gctctgttct
     2701 tggaacttac gaagtagagg gagtgccttt cttctaaaat acagattaag cgaacaaaga
     2761 agtttgaatt tttttcaaac ttcttttttt attgtttggt ccaaaaaata caatgaaatg
     2821 ttctgctaaa gatagttttt tagtgcattt tattttcaaa atatgttgaa aacggttgta
     2881 taacgaataa taataattga tcgaaaaatc atttcacaaa gtaatgctta atttatagtt
     2941 gaccaaggaa gaaatacatg ataaatttaa cagcgttgat tctgaagtgg atgttatatc
     3001 acatttctaa aaaatttaaa aaatagttat tgacatgtta ctaacgacat gataagataa
     3061 ctgagtcgtt aaaaaagaac cacttgcgaa gcttgattct atcgaaaaaa acttcaaaaa
     3121 agttcttgac aaataacaaa cgataagtta tgataaatga gttgctgaaa gatttcgaaa
     3181 aacgaaatcg aaaaaaactt ttaaaaaaga gttgacaatc gtttgtctct ctgatatgat
     3241 ataaaagttg ct
//
LOCUS       DAFBVQ010000135         3215 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.141, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000135 DAFBVQ010000000
VERSION     DAFBVQ010000135.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3215)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3215)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3215
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.141"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(133..306)
                     /locus_tag="LLC22_002835"
     CDS             complement(133..306)
                     /locus_tag="LLC22_002835"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002288514.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar ABC transporter permease"
                     /protein_id="HBK5436029.1"
                     /translation="MIFLLTVNGPTNSNFYGAGSTDLLVTWLYLTVTKIDYNLASVIG
                     ILIFIYMQKFIYY"
     gene            754..3116
                     /locus_tag="LLC22_002836"
                     /pseudo
     CDS             754..3116
                     /locus_tag="LLC22_002836"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016625383.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="phosphoketolase family protein"
BASE COUNT         1107 a          577 c          670 g          861 t
ORIGIN      
        1 aaatcagggg ttgcgggatt tttttgtttt cattaagacg tattacctaa gagttccatg
       61 actttagtct tgcggcgtgt cagctaacca aaaaagagaa aaagaaaagt aaaaaattcg
      121 actttctttt ttctagtagt atataaattt ttgcatatag ataaagatca agataccgat
      181 aacggaagct agattgtaat ctattttagt gacagtcagg tatagccaag taactagaag
      241 atcagtggaa cctgcaccat aaaagtttga gtttgtcggt ccgttgacag ttaaaagaaa
      301 aatcacgttg aagttattga tatttccgat tacgccgctt cgatttggtc acgatccaaa
      361 ttttggataa tccctgtaga aattagcata gtagctggga taccaattca catattgaca
      421 aagataacag agacttttac ataaaacgga tcaatcagga aaggaattgc tcgatccagc
      481 cccagttttc cagcaatgtg ttaactggcc cagcgtcatt cagcaaatta tgcatgatga
      541 ggagcgaaat gaactgcgga acagccattg tgataacgac aagttttttg gatcaatgta
      601 aaaaacgtca gcgaaaggaa aaatttcgtg gttttttata cctgttcatt tggctagata
      661 taaaatccaa acaaatgaac agaagtgctt attaggtttc aattgggagt atctgcgcta
      721 gaataagagt aataatgaaa aggagtgtta tgtatggatt attctagtaa agaatacttt
      781 gataaaatga cggcttggtg gcgtgctgct aattatcttt ctgttgggca actttatctt
      841 aaagataacc ccttactgag acgtacactg aaacccgaag atgtcaaaaa acatccaatc
      901 ggtcattggg gaacgattcc tggccaaaat tttatttatg tccatttgaa ccgagtcatc
      961 aataaatatg atttgaacat gttttatatt gaagggccag gacacggcgg acaagtcatg
     1021 gtatcgaatg cttatttaga tggaagttac acagagatct atccagaagt aacggaagat
     1081 gagacaggaa tgcaaaaatt attcaaacga ttttcatttc ctggaggcat tgcttctcat
     1141 gcagcaccag aaacaccagg ttctatccat gaaggcggag agcttggata ctctctttca
     1201 catgcagtcg gagctgtatt agacaatcct gaagtaatct ctgctgtcgt gattggtgat
     1261 ggtgaagcag aaaccggtcc tttagctgga agctggttct caaatgtctt tatcaatcca
     1321 gtgatagatg gagctgtttt accgatcctt catttaaatg gtgcaaaaat agccaaccca
     1381 acgatcttgg cacgtaaatc agatggagaa ttagcaaatt actttaacgg acttggctgg
     1441 gaacctttct ttattgaagg aaatgattca gaaaaattaa atcctgttat ggctgaaaaa
     1501 atggatcaag caatcgagaa aattaaatcc atccaaaaag aagctcgcct gaagacagca
     1561 acagatgtcg tgatgccaaa atggccagta ttgatcgtac gcacaccaaa aggatggacc
     1621 ggtccaaaag aatgggacgg ggaaccaatt gaaggaacct tccgagcaca ccaagtaccg
     1681 attcctgtag atcaagaaca tatggatcat gcagatgctt tactccgttg gctgaaatcc
     1741 tatgaaccag aaaaattatt tgatgcacaa ggacgtattt tagaagaaat cagagaaatc
     1801 gcgcctactg gtgaccaaag aatggcaaaa aatcctatca ccaatggtgg aatcgatcca
     1861 agaccgctta ttatgccaga ttggaaaaaa tatactttgc aatttgaaaa accaggctcc
     1921 gttaaagcag aagatatgac cgaacttggt aaattcgttc gcgagatcat tgagaaaaat
     1981 ccagaaaatt tccgtatatt tggaccagat gaaacaaaat caaaccgatt gaatcaagtt
     2041 ttcaaaacga caaatcgcca atggatggaa aaaatcgaac cagaaaatga tgaatggctt
     2101 tcgccatctg gtcgcgtcat cgacagtcaa ttatcggaac accaagatga agggttctta
     2161 gaagggtacg ttctgactgg acggcatggt tttttgcaag ttacgaatca ttcttgcgag
     2221 tggttgactc tatgttgact cagcacttca aatggatgcg gaaatcacat gacctttctt
     2281 ggcgaaatga ttatccttcg ctaaatctca ttgcaagctc aacagtcttc cagcaagatc
     2341 acaatggata tagccaccaa gatccaggaa tattgacaca tttggcagaa aagaaggcgg
     2401 agttcatccg tgaatatctg cctgcggatg caaatacatt gctcgcagtc atggataaag
     2461 cattccgctc gtcagaaaaa atcaatttga tcatctcttc caaacatccg cgtgctcaat
     2521 tttactcagc agaagaagca gccgtcttag tgaatgaagg cttgaaaatc attgattggg
     2581 cttcgacagc aaaagaggag gaacctgaat tggtcattgc tgctgcagga acggaatcta
     2641 acttagaagc attagcagct gtaactttgc tgctggaaga attcccaaaa ctaaaaattc
     2701 ggttcatcaa tgtcgtagat ttattgaaat tacgtcatcc aagtcaagat ccgcgtgggt
     2761 tgagcgatga agaatttgat caatatttta caaaagacaa accgatctta tttgctttcc
     2821 acggttatga aacattggtc cgcacgattt tctttgatcg tcataaccat catttaatga
     2881 ttcatggcta caaagaaaat ggagatatca cgacaccatt tgacatgcgt gtagtaaatg
     2941 aacttgatcg ttatcatttg gcaaaagacg cagctttaaa aatcaaagga agtcaagcag
     3001 aagattttgc gaaaaaaatg gatcagaaat tacaagaaca tcaaaactat attcgtgaaa
     3061 atggtattga tctgccagaa gtattggatt ggaaatggaa aaatcttgac caataaaatg
     3121 ataaaatcga tcccgcaaaa tagaattttt tacattgatt aagaaactga aaaaataaat
     3181 aaaaaaaacg gaaaaaagac tggaagaatg gccag
//
LOCUS       DAFBVQ010000136         3212 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.142, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000136 DAFBVQ010000000
VERSION     DAFBVQ010000136.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 3212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..3212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.142"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..1412
                     /locus_tag="LLC22_002837"
     CDS             <1..1412
                     /locus_tag="LLC22_002837"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="LPXTG cell wall anchor domain-containing
                     protein"
                     /protein_id="HBK5436030.1"
                     /translation="PTVEGEKVEVGGTVDLTDNVTNLPALPEGTTVTDVTPGGTIDTN
                     TPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSDADKYEPTVEGEKVEIGGTVDLTDNV
                     TNLPALPEGTTVTDVTPGGTIDTNTPGNYEGVIEVTYPDGTKDTVKVPVEVTDNRSNA
                     DKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYAWKEKVDVSTAGNKKGTIVVTY
                     PDGSSDEVEVDVTVTDTRSDADKYNPEGQKVTTDLNKEPDASEGIKNKEDLPKGTTYT
                     WKEKVDVSTAGNKKGTVVVTYPDGSKEEVEVTISVVDKKAPNKPQVDPITEGDQIVTG
                     KTEPNAEVTVTLPDGSQHHGTADKNGNFTVKVPKLEAGTKVIVTATDESGNTSEPTNV
                     VVSSNKKDSGKNGSKGSKTDNQGSNSNQDKNRGKSQSSKVFPKTGESDSNIFTISGGL
                     ILLGTLGLLGYKNRKKENE"
     gene            1546..2889
                     /locus_tag="LLC22_002838"
     CDS             1546..2889
                     /locus_tag="LLC22_002838"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297337.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="FAD-dependent oxidoreductase"
                     /protein_id="HBK5436031.1"
                     /translation="MEKIVIIGSNHSGLAAARFLNLSDSNYEVILIDKKSEISYLECG
                     TSLFIKGEVSNLEDLFYQNRMTLNSEIKKLFLETEVDKIDIQNKKISCVKKDGTRFSQ
                     EYDKVILATGSKQIMLDIPGNNLANIFSIKNFPNAKEIFKALDDSTIKKVGIIGAGYI
                     GVEIAEAIRKRGKEVYLFDVADRVLSTYYDRSFSDKVEEILSKNGIHLCLSESPKKYL
                     GRKKIEKIVTTSGTQYSMDMVVQAIGFLSNSPIGEKELLRDVSGAYLTNEYQQTNIKD
                     IYAIGDCATTFFTSINRSSVDFSISNALRTAYIATQHINNQDFTPSGSQFTNGFSIFN
                     YNFYAAGLNLKTARLLSESIDYIEIEDFIRPAFLRKNSRVKLRISFEKNTKRIVGVQL
                     CSQEDLSGLLSMFSLAIEEQITLDKLKMLDYLFHPSFSQPYNFILKAVTGLNIET"
     gene            3001..>3212
                     /locus_tag="LLC22_002839"
     CDS             3001..>3212
                     /locus_tag="LLC22_002839"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302451.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5436032.1"
                     /translation="MKKSLKLASAVILMSQLLIATPFHVLASENSTYKIAKERTETTE
                     MSNSDVTAESSELLTTSSSESSTTSNA"
BASE COUNT         1273 a          446 c          613 g          880 t
ORIGIN      
        1 aaccaacagt agaaggcgaa aaagtagaag ttgggggcac agtagatcta acagataatg
       61 ttactaactt gccagcgtta ccagaaggaa caacagtaac agatgttact cccggcggta
      121 caattgatac caacacacca ggtaattacg aaggtgtcat tgaagtaacg tatccagacg
      181 gtacgaaaga tacggtgaaa gttccagtag aagtgacaga caatcgttct gacgccgata
      241 aatatgaacc aacagtagaa ggcgaaaaag tagaaattgg aggcacagta gatttaacag
      301 ataatgttac taacttgcca gcgttaccag aaggaacaac agtaacagat gttactcccg
      361 gcggtacaat tgataccaac acaccaggca attatgaagg tgtcattgaa gtaacgtatc
      421 cagacggtac gaaagatacg gtgaaagttc cagtagaagt gacagacaat cgttctaatg
      481 cagataaata caatcctgaa ggacaaaaag tgactacaga cttaaataaa gagccagatg
      541 catctgaggg aattaagaac aaagaagatt taccaaaagg aactacttat gcttggaaag
      601 agaaagtaga tgttagcaca gctggaaata aaaaaggtac tattgtagtg acatatccag
      661 atggatcatc tgatgaagtt gaagtagacg ttacagtgac agatactcgt tccgatgcag
      721 ataaatataa tcctgaagga caaaaagtga ctacagactt aaataaagag ccagatgcat
      781 ctgagggaat taagaacaaa gaagatctac caaaaggaac tacttatact tggaaagaaa
      841 aagtagatgt tagtacagct ggaaacaaaa aaggtactgt agtagtaaca tatccagatg
      901 gatctaaaga agaagtagaa gttactattt ctgtagtaga taaaaaagca ccgaataaac
      961 ctcaagttga tcctattaca gagggtgacc aaattgttac tggtaaaact gaaccaaatg
     1021 cagaggtgac agttacatta ccagacggaa gtcaacacca tgggacagct gataaaaatg
     1081 gtaattttac agttaaagtt cctaaattag aggcagggac aaaagtgata gtaactgcaa
     1141 ctgatgaatc tggtaatact agtgaaccta ctaatgtagt tgtttcttcc aacaaaaaag
     1201 acagtggaaa aaacggtagt aaaggtagta agactgacaa tcaaggtagc aacagcaatc
     1261 aagacaaaaa tagaggcaaa agccagtcct caaaagtttt tcctaagacg ggagagagtg
     1321 acagtaatat ctttactatt agcggtggtt taatactgtt aggaacgtta ggattattag
     1381 ggtataaaaa tcgaaaaaaa gagaatgaat agaaaatcaa tttcttaagt cttctctgag
     1441 aagaggaaga atctttttct tcctcttttt gcttttttat gatgggaaat aagtgttagt
     1501 taaagatgaa tatacttttt atagaaagga aaagaatgta attaagtgga aaaaatagta
     1561 attattggtt caaaccattc agggctagcc gcagctcgat ttctaaactt aagcgattca
     1621 aattatgaag ttattctaat cgataaaaaa tcagaaatta gttacttgga atgtgggaca
     1681 tcgttattta taaaaggaga agtaagtaat ttagaagatc ttttttatca aaatagaatg
     1741 acactaaatt ctgagataaa aaagttattt ctagagacag aagttgacaa aattgatatt
     1801 caaaataaaa agattagttg tgtaaaaaaa gatggtacaa gattctctca agaatatgac
     1861 aaagttatat tagctacagg ttcaaagcaa attatgctag atataccggg gaataattta
     1921 gctaatattt tttcgataaa gaattttcca aatgcaaaag agatttttaa agctttggat
     1981 gatagtacta ttaaaaaagt aggaattatt ggagcaggat atattggagt tgaaattgct
     2041 gaagccataa gaaaaagagg gaaagaagta tatcttttcg atgttgcaga tagagtgttg
     2101 tcgacttatt acgaccgtag tttttcagat aaagttgaag aaatactatc aaaaaatgga
     2161 atacatcttt gtctatcaga aagtcctaaa aaatatttag gaagaaaaaa gattgaaaaa
     2221 atagtcacta caagtggtac ccaatactct atggatatgg tcgtacaagc tataggattt
     2281 ctatctaata gtccaattgg ggaaaaggaa ctcttgagag atgttagtgg agcatatcta
     2341 actaatgaat accagcaaac aaatataaaa gatatatatg ctattgggga ttgtgctaca
     2401 acttttttta cgtccattaa tagaagtagt gttgattttt ctatttctaa tgctctaaga
     2461 acagcttata ttgcaactca acatattaac aatcaagatt ttacaccttc tggttcccaa
     2521 tttacaaatg gcttttctat atttaattac aatttttacg cagcaggttt gaatttaaaa
     2581 acagcacgat tattaagtga gtctatagat tatatagaaa tagaagattt cattagacct
     2641 gcttttttga gaaaaaatag tcgtgtaaaa ttaagaatta gctttgaaaa aaatacaaag
     2701 agaatagtag gtgtacaact ttgtagtcaa gaagatttat ctggactatt atcaatgttt
     2761 tctcttgcta tagaagaaca aattacatta gacaaattga aaatgttaga ttatttattt
     2821 catcctagtt ttagccaacc ctataatttt attttaaagg cagtaacagg attaaacatt
     2881 gaaacataat cgttactaaa tgaaatcaag aaatatactg tattactcaa ttcattgaaa
     2941 atatttatca taatttttaa tagaaaacac tattaaagag aaaaaagaga ggtaaatcaa
     3001 atgaaaaaat ctttaaaact tgcatcagca gttatattaa tgtcccaact ccttatagca
     3061 acacctttcc atgtgttggc aagcgaaaat tcaacataca aaattgcaaa agaaagaacc
     3121 gagacgactg aaatgagtaa ttccgatgta acagcagaga gtagtgaact tttgacaact
     3181 tcatcaagtg aaagtagtac gacttcaaat gc
//
LOCUS       DAFBVQ010000137         2861 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.143, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000137 DAFBVQ010000000
VERSION     DAFBVQ010000137.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2861)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2861)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2861
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.143"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            4..2376
                     /locus_tag="LLC22_002840"
     CDS             4..2376
                     /locus_tag="LLC22_002840"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347694.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436033.1"
                     /translation="MAEEKEPLDNSRLGKSKRKLVRLQNELNEQIEKMFEHQRKTNGQ
                     PMNDKRNGHSWFRQQERLENKVHSLREEIKQQEKQVEKLERQEELKEMGYNKYGGLDM
                     TIENIPRIKEEIERFEKGESTFSAATIRKYQRKLETLEQLKERSEKGKENLLPEVQAI
                     IDSGRVTQWKKNPTIYFLKDYRKVALELNENGGFEESKKYQATSEEEKAAVRELLEEA
                     APTDSLKEKENDHFYRVEFNENDPEKGLKSYGGEIVTLELIDQLKTLDNQYAAEAGYY
                     KFYFEEVKNGEVVDQIRMDLGDGVNSNQPIYLELAKLCEQVPEKEQKQTVKNEPVSKE
                     QMQSKETKTKQKGYQKRTAEEIKQEVKSLSQQALDAVKKHTHSPEDVKELLNFMSRFP
                     ERSFRNQLLIEEQFPGATACLGRAALKKEGIYIKKGEQGNKIFVRKTVKGFYEKGRGF
                     VRETEATPEDKKRIESGQIEVIKKPYYTIEKVFDITQTQLKPEDYPKIFPNRVFDFQL
                     DKKGQSELQAGIQAVANNIGIQIRDMTESEVYQRELGQARGAYVRNEFTGEEEIVMNT
                     RNTPTQHLATSIHELAHARMHKFSELDTATKELQAEMTSYIVCKHFGMDTSEKAIPYI
                     AAWTKNGQTLDDKEAAERGKIMNDVSRVANEFIQTISNEINQYREREPEIQPAEVKQE
                     HKNTVETAENKNIVPVGSLWIDKKDGKVMEEDTGRTLHLKDAAFIEDPQHNQVILKGK
                     SYGKEIQTALPSEEFALGNPFRFSLETVSEVAKRKNEIYYEQQLSQKERV"
     gene            2437..>2861
                     /locus_tag="LLC22_002841"
     CDS             2437..>2861
                     /locus_tag="LLC22_002841"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436034.1"
                     /translation="MTEKKMSLIDRCKQIDIVDFARNNGMAVVNKGRDYRLEDHDSFV
                     FDRRKQRFYWNSQNISGDIIELAKLFFIDKEIQDSKQQFKAATDFILKNEDKTERVEN
                     LHFETEKYKDHPVDYQPLTEKGRNYLKEERKLPEWLIDYA"
BASE COUNT         1144 a          455 c          620 g          642 t
ORIGIN      
        1 gacatggcag aagaaaaaga accactagac aatagtcgct tgggaaaatc caaaagaaaa
       61 ttagtacgat tgcaaaatga attaaacgaa caaattgaga agatgtttga acaccagaga
      121 aagaccaacg gtcagccaat gaacgataag agaaatgggc attcttggtt taggcaacaa
      181 gaacgtttag aaaacaaagt gcatagtctg agagaagaga tcaagcaaca agaaaaacag
      241 gtagaaaaac ttgaaagaca agaagagcta aaggaaatgg gctataacaa gtacggcggc
      301 ctggatatga caatcgaaaa tattccaaga atcaaagaag aaatcgaacg ctttgaaaaa
      361 ggtgaatcga ctttttcagc cgctacgatc cgaaaatacc aacggaaatt ggaaacatta
      421 gaacagctga aagaaagatc agaaaaagga aaagaaaatc ttcttcctga agtacaagca
      481 attattgaca gcggacgagt gacgcaatgg aaaaaaaatc caaccattta ttttttgaaa
      541 gactatcgaa aagttgcttt agaactgaat gaaaacgggg gatttgagga atcaaaaaaa
      601 taccaagcca cgtcggaaga ggaaaaagca gctgttcgtg aattacttga agaggctgcg
      661 ccaactgatt ctttgaagga gaaagaaaac gatcatttct atcgagtaga attcaacgaa
      721 aatgatccag aaaaaggatt gaaaagttat ggtggggaga tcgtaacatt agaattgatc
      781 gatcaactca aaacgttgga taaccaatac gccgcagaag caggttatta taaattctat
      841 tttgaagaag tgaagaacgg agaagtagtc gatcagatcc gaatggatct aggggatggc
      901 gtcaacagta atcaacccat ctatttagag ttagcaaaat tgtgcgaaca agtacctgaa
      961 aaggaacaaa aacaaacggt caaaaatgaa cctgtttcga aagaacaaat gcagtcgaaa
     1021 gaaacaaaaa caaaacaaaa gggctatcaa aaacgaacgg cagaagagat taagcaagaa
     1081 gtcaaatccc tttcgcaaca ggcactggat gcggtgaaaa agcataccca ttctcctgaa
     1141 gacgtgaaag aacttttgaa ttttatgtct cgttttccag aacgatcctt tagaaatcaa
     1201 ttattgattg aggaacaatt tccaggtgca acggcttgtt taggtcgtgc tgcgttgaaa
     1261 aaagaaggaa tctatatcaa aaaaggggaa caagggaaca agatctttgt cagaaaaacg
     1321 gtcaaaggat tttatgagaa aggacgtggc tttgttcgag aaacagaagc tacaccagaa
     1381 gataaaaaac gaatcgaaag tggtcaaatc gaagtgatca aaaaacctta ctacacgatt
     1441 gaaaaagtgt ttgatatcac acaaacacag ttaaaacctg aagactatcc gaaaatcttt
     1501 ccgaaccgtg tctttgattt tcaattggat aaaaaaggac agtcagaact tcaagctggg
     1561 attcaagcgg tagccaacaa tattggaata caaattcgag atatgacaga aagtgaagtc
     1621 tatcaaagag aattaggaca agcacggggg gcgtatgttc gtaacgaatt tactggcgaa
     1681 gaagaaatcg tcatgaatac tcgaaatact cctacgcagc atttagctac aagtattcat
     1741 gaattagccc atgcaagaat gcacaaattt tcagaattag ataccgcaac taaagaattg
     1801 caggcagaaa tgacttctta tattgtgtgc aaacattttg gaatggacac ttcggagaaa
     1861 gctattcctt atattgcagc atggacgaag aatggtcaga cgttggatga taaggaagcg
     1921 gcggaacgtg ggaaaatcat gaatgatgtc agccgtgtcg caaatgaatt cattcaaacc
     1981 atttctaatg aaatcaatca atacagagaa agagaaccag agatccaacc agcagaagtg
     2041 aagcaggagc ataaaaatac tgtagaaacg gcagagaata agaatattgt gcccgttggt
     2101 tcactttgga tcgacaagaa agacgggaaa gtaatggaag aagatacggg tcgaacgtta
     2161 catttgaagg atgcggcgtt tattgaagat ccgcagcata atcaagtgat tttaaaagga
     2221 aaaagttatg gaaaagagat tcaaacggcg ttaccttcag aagaatttgc gctaggaaat
     2281 ccattccgat tttcacttga aacagtgtca gaagtggcca aacgaaaaaa tgaaatctat
     2341 tatgaacaac aattgtcaca aaaagaacgc gtataaaaca agtaaaaaag actatctgaa
     2401 aaacggatag tcttttttct tttgggaggt ttgaaaatga ccgaaaaaaa aatgagtctt
     2461 attgatcgat gtaaacagat cgatatagtg gattttgctc gaaacaatgg aatggctgta
     2521 gtcaataaag gacgagacta tcgcttagaa gaccatgatt catttgtttt tgatcgaaga
     2581 aaacaacgtt tttattggaa cagtcaaaat attagtggcg acattattga attagctaaa
     2641 ctttttttca tagacaaaga gatccaagac tctaagcaac aatttaaagc agccacagat
     2701 tttattctaa agaatgaaga caaaacagaa cgagtagaaa atcttcattt tgagacagaa
     2761 aagtacaaag atcaccccgt tgattatcaa ccactcacag aaaaaggaag gaattatctg
     2821 aaggaagaac gaaaactacc agagtggctg attgattatg c
//
LOCUS       DAFBVQ010000138         2666 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.144, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000138 DAFBVQ010000000
VERSION     DAFBVQ010000138.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.144"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..318
                     /locus_tag="LLC22_002842"
     CDS             <1..318
                     /locus_tag="LLC22_002842"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324485.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="GNAT family N-acetyltransferase"
                     /protein_id="HBK5436035.1"
                     /translation="KAIIPENLDEVKLYLWEDNGEIVGFSGVSAEELVMLFLDPDFIG
                     KRYGSQILIELIETEDIKRIDVNSQNKYAKHFYLSHGFEIESEEDLDGFGKPYPITHL
                     VKK"
     gene            732..1550
                     /locus_tag="LLC22_002843"
     CDS             732..1550
                     /locus_tag="LLC22_002843"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341332.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAD family hydrolase"
                     /protein_id="HBK5436036.1"
                     /translation="MNKNPHNLKLVAVDMDGTFARTDYTYDIPRFKAVLSRMKAVDCQ
                     FVVASGNQYYQLRSLFPNYYDELSFVAENGAFVKDKTEVLFSADMPRKAIEVVLDLCK
                     DYPEVKNVMCGLNSAYCERGKVSQAFFDLTNIYYHRLEWVADFAEVQDKILKFAPTMP
                     VEKTEFYVELFREKLAGLLVPTSSGHGSVDLILSECHKTFGLKMLVERLGINPDQCVA
                     FGDGGNDIEMLEYCGLSYEMDNATEAVKQVAKHQCPSNDEDGVLVTLDRLFPNT"
     gene            complement(1623..1982)
                     /locus_tag="LLC22_002844"
     CDS             complement(1623..1982)
                     /locus_tag="LLC22_002844"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293559.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-sulfur cluster biosynthesis family protein"
                     /protein_id="HBK5436037.1"
                     /translation="MSDNLFLEVQPEVFKQVPRLKDGFLLTLNDGSNQFSSAEGCCMI
                     GDHFLLVSTQHYIPAYDLTIPCEEATVKTSEYDTTFINGHLVLEVTPSNQTIRLKNES
                     GILDSNVQVYFDSSDAS"
BASE COUNT          924 a          371 c          471 g          900 t
ORIGIN      
        1 aaagcaatca ttcctgagaa cttagatgag gttaaacttt atttatggga agataacgga
       61 gaaattgtcg gttttagtgg tgtaagtgca gaagaattag ttatgctatt tcttgatcca
      121 gattttattg gtaagcgata tggtagtcaa atattaattg agctgattga aactgaagat
      181 ataaaaagaa ttgatgttaa tagtcaaaat aaatatgcaa aacattttta tttaagccat
      241 ggatttgaaa ttgaatctga agaagactta gatggttttg gtaaaccata ccctataacg
      301 catttagtaa aaaaataatt catgaatggt ttattacctg attgaacatg aataaaagta
      361 atatttttat tttgatggcc tatttctagg ttatgaatta tccagatcaa atttgtgtat
      421 tacattcagt aataaggtgc ttatcttagg atcaacttat gatactagct gaccaaggat
      481 gtaccagtta tagaaaatca gttaaagtaa aaatgataaa aatcttatgt caacactgat
      541 ttaggctgac ctgtgggtta ggagaaagac aggtcggtag cttttaatac aaaaaatggc
      601 ttgtatgtat ctagatagtt aactgaaatt agaaatgttc ttatttttaa cggagtaaga
      661 aaaataggct gctttaggtc tgaatacttt ttcaatataa tgaagatatc aaaggcgaca
      721 ggagtgtttt tatgaataag aatcctcata atctaaagtt ggtagcagta gatatggatg
      781 gaacatttgc tcgtactgat tacacatacg atatcccaag gttcaaggct gttttatcgc
      841 gaatgaaagc tgttgattgt caatttgttg ttgcaagtgg aaatcaatac taccaattga
      901 gatcgttatt tccaaattat tatgatgaat taagttttgt tgctgaaaat ggtgcttttg
      961 ttaaagataa aacagaggta ctattttcag ccgatatgcc tagaaaagcg atcgaggtgg
     1021 tccttgattt atgtaaagac tatcctgaag taaaaaatgt gatgtgtggt ctgaatagtg
     1081 cctactgtga aagaggaaag gtgagtcaag cattttttga tctaaccaat atctattacc
     1141 atagattaga atgggtagct gattttgcag aagttcaaga taaaatttta aaatttgctc
     1201 cgactatgcc tgttgaaaaa accgaatttt acgttgaatt gttccgtgaa aaattagccg
     1261 ggctattagt acctaccagt agtggtcatg gttctgtaga cttgattctt tctgagtgcc
     1321 ataaaacttt cggcttgaaa atgttagttg agcgcttggg gattaatcct gaccagtgcg
     1381 ttgcttttgg agatgggggc aatgacattg agatgttgga gtattgtggt ctgagttatg
     1441 aaatggataa tgcaacggaa gctgttaagc aagttgctaa gcatcaatgt ccttcaaatg
     1501 acgaagacgg tgttttagtg acgctcgatc gattgttccc taacacgtaa acactaggta
     1561 attcatcaaa aaacctcgat ataagaaata ttcgaggttt taaaactata tttagaacag
     1621 atttacgaag cgtctgatga gtcaaaatag acttggacat tgctatctaa aataccactt
     1681 tcattcttta aacgaattgt ttgatttgat ggagttacct ctaatactaa atgcccatta
     1741 ataaaggtag tatcgtattc agatgtttta actgttgctt cttcgcaagg tattgttaaa
     1801 tcatatgctg gaatataatg ttgtgtggaa actaataaaa aatgatcacc aatcatacag
     1861 catccctctg ctgaagaaaa ttgattagag ccatcattta aagttaacaa gaatccatcc
     1921 tttaaacgag gtacttgctt aaatacttct ggttgtactt ctaaaaataa attatcgctc
     1981 attttcacga ccaccatcga cttccacagt tgaaattgac attttattta acacacctat
     2041 tcccccttaa ctataactca attctatata aaaaatattc tattctcaaa taattgaact
     2101 tttcaaatcg ccaatttact tcggctttat cagagctcat tcatatcaag agcgattaac
     2161 gctgtaaaaa ttaaaccgaa gatctgataa attttctcta ttttctacaa tatttaaaac
     2221 gcttccttag tctattatat atctatttct cttaggagta tgtttagatg tttgaataat
     2281 agttgcccaa ctttaaaggt tattcttata atattttact tcattttcca atagaaaatt
     2341 caaaggatta ctggtttttc taaaatagtt tagtttaaat acataagtat cctccgacac
     2401 tgtattagtt cataatcatc taaatacaaa attttcaaat aaaaatattt caagctctat
     2461 cgttgacgaa tgtaaacgat acttataaag taatagaaat tgattacatt tgtaaactta
     2521 aaatggttaa tttatctcac ataaaactaa gaataaaata atgattaaaa gtggttagtt
     2581 tttatacgat ttagcctatc ggtaaaaatg aattagagag tgtaaaatat tttgtgtaaa
     2641 tgaaaaaatc catacaaaaa aggaag
//
LOCUS       DAFBVQ010000139         2640 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.145, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000139 DAFBVQ010000000
VERSION     DAFBVQ010000139.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2640)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2640)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2640
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.145"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            112..1311
                     /locus_tag="LLC22_002845"
     CDS             112..1311
                     /locus_tag="LLC22_002845"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcF family protein"
                     /protein_id="HBK5436038.1"
                     /translation="MNLTRDLIFLVLYLIGVFSIVYWRKQKKDPSLFFYGSTWTFTVI
                     LTYFVVLEIFYSTFYFLIPLLFFSIFAFSYFTEKRRLLNGLLFNVLLISFGIYLFVLL
                     YETQNIFLGGLIALITIPLLLVLLFGIYGLIVFLFWNGVTVLRRESHSLANLLTLILA
                     IFLTLFLVFDFFLLKYLPQWINALFFCVPLILIYLFIVFYNFLTVSFLYQFNRPRYNQ
                     DFIVVLGAGLINGETVSPLLAKRINKAIAFYRAQSRATLNPPILLMSGGQGADEKVPE
                     AIAMKQYAMEQGIPERDILVETNSTTTLENMLYSKEIMDQQMKGPYRAIFSSNNYHIF
                     RAGLYARQAKLKANGIGAKTAFYYLPNAFLREYLAILMMNKKRHMIICGLLFAGSAFL
                     SLITLLF"
     gene            complement(1338..2606)
                     /locus_tag="LLC22_002846"
     CDS             complement(1338..2606)
                     /locus_tag="LLC22_002846"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002291753.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="voltage-gated chloride channel family protein"
                     /protein_id="HBK5436039.1"
                     /translation="MEKQLPSPVRILVYMLKWLVITAILGIFMGSLSAFFLNSLTVVT
                     DIRLSHPWLLCLLPVSGALFAYLYAYHGGLSSRGNNLVIDQGNGGEEKIPLRLIPLTL
                     FGTITTHLFGGSVGREGTAVQMGGALADNTARLFRLDKSEREILIISGISAGFSSVFG
                     TPLAGTLFGLEVLAIGKVRTEAIFPSFFAALFANFMTESYGVSHLHYQMGVIPEWSML
                     LFFKVFVAGIAFGLIGWVFSRSIVFLKARYAQWIPHPVCRNTIGGAVVVAAALILQTQ
                     RYLGLSLPLLQESFNGQAHVYDFIGKLFFTVLSLGAGYQGGEVTPLFEIGATLGAALA
                     PLLHVSVPFLAGLGFIGVFSGATNTPIACFVMGIELFGSQAAVYFFMICLISFMCSGN
                     SGIYSAQQVAVKKGILFLPIVKRMKEKNKV"
BASE COUNT          791 a          573 c          469 g          807 t
ORIGIN      
        1 ataagaaaaa catctttcca tcggaaagat gtttttttgc tttttctagt ttaaataaca
       61 gcttttttca tctattttcg ttatactgta taagaaaaag gagttgaatt tatgaatcta
      121 accagagatc tgatcttttt agttctctat cttattgggg tattctctat cgtttattgg
      181 cgaaaacaga agaaggatcc ttccttgttc ttttacggca gtacgtggac atttacggta
      241 atcttaactt attttgtcgt gttggaaatt ttttattcga ccttttattt tttgattcca
      301 ttgttgttct ttagtatctt tgctttttct tatttcacag aaaaacgaag gctactgaat
      361 ggtcttttat tcaatgtttt actcatcagt ttcggcatct acttgtttgt cttgctgtat
      421 gaaacgcaaa atatttttct tggcggactg atcgccttga tcacgattcc attgctactt
      481 gtccttttat ttggtattta tggattgatt gtttttcttt tttggaacgg ggtcacagtt
      541 ttacgtagag aatcgcattc attagctaat cttttaacgt tgatactagc catttttctt
      601 acactgtttc ttgtttttga ctttttcttg ttaaaatatt tgccgcaatg gataaatgct
      661 ttgtttttct gcgttcccct gatcttgatc tatctattta tcgtattcta caactttttg
      721 actgtctcat tcttgtatca gttcaaccgg cctcgataca atcaagactt catcgttgtg
      781 ttaggcgctg gattgatcaa tggagaaaca gtttctcctc ttctagccaa gcgaatcaat
      841 aaggcaattg ctttttatcg ggctcaaagc cgtgctacat taaatccgcc catcttattg
      901 atgtctggcg ggcaaggagc agacgaaaaa gtaccagagg ccattgcgat gaaacaatat
      961 gccatggaac aaggaatccc tgaaagagac attcttgtcg aaaccaattc gacaaccact
     1021 ttggaaaaca tgctctattc aaaggaaatc atggatcagc aaatgaaagg gccataccgc
     1081 gcgatcttta gttccaacaa ttaccacatt tttagagccg gtctttatgc gcggcaagcc
     1141 aaattgaaag caaatggtat tggtgcaaaa acagctttct actacttgcc taatgcgttt
     1201 ttaagagaat acctcgccat cttgatgatg aacaaaaaaa gacatatgat catttgcgga
     1261 ttgcttttcg caggctccgc attcttatcg ctgattactt tacttttcta aaaaaacaag
     1321 gtgtgacaaa acatatgtca caccttgttt ttttctttca ttctcttaac tattggcaaa
     1381 aagagtatcc cttttttgac cgctacttgc tgagcagaat aaataccgct gttgcctgaa
     1441 cacataaagc tgatcaagca gatcataaag aagtatactg ccgcttgtga accgaacaat
     1501 tcgatcccca tcacaaagca ggcaatcggt gtatttgtcg caccagaaaa tactccgata
     1561 aagcccaatc ctgcaagaaa aggaacagaa acatggagca aaggcgctag tgctgcacca
     1621 agcgttgcac caatttcaaa caatggtgtc acttctcccc cttgatatcc cgcgcctaaa
     1681 gacaaaactg tgaagaataa cttcccaata aaatcataga catgtgcctg tccattaaat
     1741 gattcttgaa gtaacggaag actcaatccg agataacgtt gtgtttgcaa aatcaatgct
     1801 gctgccacaa ctacagctcc acctatcgta tttcgacaaa caggatgagg aatccattgt
     1861 gcatatcgcg cttttaaaaa gacgatcgaa cggctgaata cccaaccaat caaaccaaaa
     1921 gcaatcccag caacaaaaac tttgaagaac agcaacatac tccattcagg aatcacaccc
     1981 atttggtaat gtagatgaga aacaccatag ctttctgtca tgaaatttgc aaacagtgca
     2041 gcaaagaagc tagggaagat cgcttctgtt cggactttcc cgattgccaa cacttctaat
     2101 ccaaataatg ttccagctaa aggtgtgcca aatacagaac taaaacccgc actgattcca
     2161 ctgataatca agatttcccg ttctgattta tccaatcgga acaaacgtgc cgtattatct
     2221 gctaacgctc cccccatttg gactgctgtt ccttcacggc caacagatcc cccaaataaa
     2281 tgggtagtta tggttccaaa cagtgtaagt ggaataagcc gcaacgggat tttttcttct
     2341 ccaccatttc cttgatcgat cactaagttg tttccacgac tagaaagtcc gccgtgatac
     2401 gcatagagat aagcaaaaag cgcaccacta actggtagta gacaaaggag ccaaggatgt
     2461 gatagtcgga tatctgtcac aactgtcagg ctatttaaga aaaaagcaga caagctcccc
     2521 atgaatatac cgagaatcgc tgtgatcacc agccacttca gcatatacac taaaatgcgt
     2581 actggactcg gtaattgttt ttccataaaa aattcctcct caataaaaaa acgcctacta
//
LOCUS       DAFBVQ010000140         2634 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.146, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000140 DAFBVQ010000000
VERSION     DAFBVQ010000140.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2634)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2634)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2634
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.146"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            5..1150
                     /locus_tag="LLC22_002847"
     CDS             5..1150
                     /locus_tag="LLC22_002847"
                     /EC_number="2.5.1.48"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cystathionine gamma-synthase"
                     /protein_id="HBK5436040.1"
                     /translation="MHIQTKLIHGGISEDPTTGAVSVPIYQTSTYRQDGVGQPKQYEY
                     SRSGNPTRFALEELIADLEGGVRGFAFSSGLSGIHAVFSLFQAGDHILLGDDVYGGTF
                     RLFDKVLTKNGLEYTIIDTSNLDKIEQSIKPNTKALYLETPSNPLLKITDLEKSATLA
                     HQHGLIVIADNTFATPYFQRPLDLGSDIVVHSGTKYLGGHSDVVAGLVTSNHKDLADQ
                     IGFYQNAIGAVLGPQDSWLLQRGIKTLSVRMEEHQKNAFVVADFLFSHPAVEKVYYPG
                     LPDHELHGVAKQQMSGFSGMISFTLKNEESAIPFVESLQLFTLAESLGGVESLVEIPS
                     VMTHASIPKEKREEAGIKDGLIRLSVGIEYGQDLINDLAQAFDRIKN"
     gene            1321..1779
                     /locus_tag="LLC22_002848"
     CDS             1321..1779
                     /locus_tag="LLC22_002848"
                     /EC_number="4.4.1.21"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005879048.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="S-ribosylhomocysteine lyase"
                     /protein_id="HBK5436041.1"
                     /translation="MRMNVESFNLDHTKVKAPYVRVADRKTGAHGDVIIKYDVRFKQP
                     NKEHMDMPSLHSLEHLTAELIRNHADYIVDWSPMGCQTGFYLTVLNHESYEDILDVLE
                     ATMKDVLEATEVPASNETQCGWAASHTLEGAQALAREFLAKRDEWSEVEA"
     gene            1938..2408
                     /locus_tag="LLC22_002849"
     CDS             1938..2408
                     /locus_tag="LLC22_002849"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344587.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glutathione peroxidase"
                     /protein_id="HBK5436042.1"
                     /translation="MSIYNFETTLEDGTVYSLKKYAGKPIIIVNTATKCGLAPQFKQL
                     EELYQAYQTQGLVILGFPSNQFKQELDSATEAAEACKTTYGVTFPMHQLIDVNGENTD
                     PLFTYLKNEAPGTVTKAIKWNFTKFLIDRNGKVIERFAPQTSPLKMTAAIESVL"
     gene            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="LLC22_002850"
     rRNA            complement(2461..2576)
                     /gene="rrf"
                     /locus_tag="LLC22_002850"
                     /product="5S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00001"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00001"
BASE COUNT          863 a          504 c          496 g          771 t
ORIGIN      
        1 aaacatgcac attcaaacaa aattgatcca cggaggcatc agtgaagatc ccacaacagg
       61 agctgtcagt gtacctattt atcaaacatc cacttatcgg caagatggcg tcggccagcc
      121 taaacaatat gaatattcaa gatctggtaa tcctactcgt tttgcattgg aagaactgat
      181 tgctgatttg gaaggcggtg ttcgaggatt cgctttttct tctggtcttt ctgggattca
      241 tgccgttttt tctctttttc aagctggcga tcatatctta ttaggagatg atgtctatgg
      301 aggaacattc cgtctatttg acaaagttct tactaaaaat ggtctcgagt acacgatcat
      361 agatacgagt aatcttgata aaatagaaca atccatcaaa cccaatacaa aagcacttta
      421 tcttgaaaca cctagcaatc cgcttctaaa gattactgat ttagaaaaaa gtgccactct
      481 ggctcatcaa catggattga tagttattgc tgacaataca tttgctactc cttattttca
      541 aagaccttta gatctcggtt ctgatatcgt tgtccatagc ggtaccaaat atctaggcgg
      601 acacagcgat gtagtagctg gtttagtgac ttctaaccat aaagatctag ccgatcagat
      661 cggattttac caaaatgcta tcggagccgt acttggtccc caagatagct ggttacttca
      721 gcgcggaatc aagacactaa gtgttcgtat ggaggaacat caaaaaaatg cttttgtggt
      781 agctgatttt ctattttctc atccagcagt agaaaaggtc tactatccag gattacccga
      841 tcatgaactc catggagttg ctaagcagca gatgagcggc tttagcggaa tgatttcttt
      901 tactttaaaa aatgaagaat ctgctattcc atttgttgaa tcactccaac tatttacttt
      961 agcagaaagt ttaggtggcg tagaaagttt agtggaaatt ccttctgtca tgactcatgc
     1021 gtctattcca aaagaaaaac gagaagaggc tggcataaag gacggcttga tccgtctttc
     1081 tgtaggaatt gagtatggtc aggatctcat aaacgattta gctcaggcat ttgacagaat
     1141 caagaactag aagtcccaat aaacgactta gcagaaaaat ctaaaaaata tttcagattg
     1201 ctacaccttg gaaacgataa gtgttagaat caagtagaaa gacgtttttg taaatttcac
     1261 taaataattc tttagtgaaa agcatcaaaa cgaatgaaca aacagatagg agtcttacaa
     1321 atgagaatga atgtcgaaag ttttaatctt gaccatacaa aagtcaaagc accttatgta
     1381 cgtgtagctg atcgaaaaac gggtgcgcat ggcgatgtca tcattaaata cgacgtccgc
     1441 tttaaacaac caaataaaga acacatggac atgccaagtc tacattcact tgagcacttg
     1501 actgccgaac taatccgcaa tcacgcagat tacatcgtag actggtctcc aatgggatgc
     1561 caaacaggct tttacttgac tgtattgaat catgaaagct acgaagacat tttagatgtt
     1621 cttgaagcaa caatgaaaga tgttcttgaa gctactgaag tacctgcaag caatgaaaca
     1681 caatgtggct gggctgccag ccatacacta gaaggtgcac aagctttggc tcgtgaattt
     1741 ttagcaaaac gcgatgaatg gtctgaagta gaagcatagt ttctaaaaga acgtaaagat
     1801 gagaagcaat atagctatct tatcttcgta ttttattaaa tatttattgt ctgaaaagag
     1861 ttctaaacgg gaaaacaaat agctagtttt cagtttagcg ctctttttat tatataaaat
     1921 agaaaggaga aaactttatg tctatttata attttgaaac tactttagaa gacggcactg
     1981 tctattcatt gaaaaaatat gcaggcaaac cgataatcat tgttaacact gcaacaaaat
     2041 gcggtctagc acctcaattt aaacaattag aagaacttta ccaagcttat cagacacaag
     2101 gtctggttat cttaggcttt ccttccaatc aatttaaaca agagctagat tcagcgactg
     2161 aagcagcaga agcttgtaaa accacttatg gcgttacctt ccctatgcat caattgattg
     2221 acgtaaatgg agaaaataca gatcctcttt ttacttatct taaaaatgaa gctcctggta
     2281 ctgtcactaa agcaataaaa tggaatttta ctaaattttt gattgataga aatggcaaag
     2341 taatcgaacg atttgcacca caaacttctc cattgaaaat gaccgctgca attgaatccg
     2401 ttctttaact taataaaaat aaaaaaagat gaactatttc tagttcatct ttttgccttt
     2461 gcgtggcgac gtcctactct cacaaggggc aacccctcac tacaatcggc gctaagaagc
     2521 ttaacttctg tgttcggcat ggttacaggt gtatccttct cgctatcgcc accacactgt
     2581 ggtgttatct tttattgagt aaattttgtt cactcaaaac tggatttgaa gtca
//
LOCUS       DAFBVQ010000141         2488 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.147, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000141 DAFBVQ010000000
VERSION     DAFBVQ010000141.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.147"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(513..1805)
                     /locus_tag="LLC22_002851"
     CDS             complement(513..1805)
                     /locus_tag="LLC22_002851"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBK5436043.1"
                     /translation="MARKKRNPDAEKLAESILNAYQPESVDDMQDALKDVFGPLFEKM
                     LQGELNNHLGYDAHSKEPKEHDNRRNGYGTKTLKTSFGEVAIDVPRDREASFEPELIP
                     KRKRDVSDIEGKVLSMYARGMSQRDIAATVEAIYGFDISHEMISDITDAVLPELEEWQ
                     ARPLAKCYAFLFVDCMYVTLRENYEAKEYAVYTILGYDLKGNKEILGLWLNQTESKNR
                     WMQVFDELKARGVEDVFFISMDGVSGLEEGAKAIFPSVIVQRCIVHLVRNALRYIPSK
                     DYKEVCRDMKKFYGASSLNAAHAAFDSFQNRWSHYSGAVVVWKRNFAHVEQLFDYGSA
                     IRKIMYTTNAVESVHSSFRKVTKKGAFSNENALLKLLYLRTKELHAKWSGGRIQNWAM
                     VLNQLMINETFSSRMKSMRFTFRNNGRFIQLCVRSKFI"
     gene            complement(2079..2339)
                     /locus_tag="LLC22_002852"
     CDS             complement(2079..2339)
                     /locus_tag="LLC22_002852"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436044.1"
                     /translation="MKKIDLINMIGMLIGILVNIVIFTDWLGVLFSNLIPILIIGICG
                     IILSILELFESRNTMNRIFACIILIVNLLPMVYFTFLYFALG"
BASE COUNT          829 a          464 c          375 g          820 t
ORIGIN      
        1 gttaattgta gcctatccac ttatattata aattcacatg attatcgaat tttattaagt
       61 tagtttttct tgtaaatctc tgttcccaat gaaactcgag acacttattt taaagaggaa
      121 acaatgtggt atttaaatag ccctcttgta tgggctactc tgtgatactt attagccatt
      181 aaactatttt acccacatag catatatttt gaaatcgttc attccgtaaa ttcaactaaa
      241 tatgcctaaa aaaataaaaa atctaagata gaataagatt tattcagtct tagatggatt
      301 tatagcaact ttttcgtaac aactttaaaa aatacgaaaa gaaagagctg ttttactctg
      361 actacgttgc taaattgtcg tttaatcatt catttaaacc aaatcttttt ttatagaatt
      421 cgttttaatc ctcctgaatc caaaaactat gaaaaccgta attaaatagt taagagtttt
      481 taaccaccat aattctctcg gctattttga aatcagataa attttgatcg gacacatagt
      541 tgaataaacc taccgttgtt acggaaggta aatcgcatac ttttcattct agaggagaag
      601 gtctcgttga tcattaactg attaagcacc atagcccagt tttgaattcg accacctgac
      661 cacttcgcgt gtaattcttt cgtgcgtaaa taaagtagtt ttaggagtgc attctcatta
      721 gagaacgctc ctttttttgt gacttttctg aagctggagt ggacactttc aaccgcattg
      781 gtagtgtaca taatttttcg aatggcacta ccataatcaa atagttgttc aacatgtgca
      841 aagttccgtt tccagacaac tacagcacca gaataatgag accaccgatt ttgaaaactg
      901 tcaaaagcag catgtgcagc gtttagagaa gaagcaccgt agaacttttt catatctcgg
      961 cagacttcct tatagtcctt acttggaata tagcgcaatg catttcgaac aagatgaaca
     1021 atacagcgct gaacaattac cgatggaaag atcgcttttg cgccttcttc gaggccagaa
     1081 acaccgtcca tcgaaatgaa aaagacatct tcgacaccac gtgctttcag ttcatcaaat
     1141 acttgcatcc agcgattttt agattctgtt tgatttaacc ataatcctaa aatctcctta
     1201 tttcctttga gatcatagcc aagaatggtg tatacagcat attctttggc ttcataattt
     1261 tctcgtaaag taacatacat acaatcaacg aatagaaagg cataacactt tgctaggggg
     1321 cgggcttgcc attcttccaa ttcaggaagg acagcgtcag tgatatctga aatcatttca
     1381 tgggaaatat caaagccata aatagcttcg acggttgcgg caatatctcg ttgactcatt
     1441 cctcgtgcat acatggaaag aaccttccct tcgatgtcgg agacatctcg ttttctctta
     1501 ggaattaact ctggttcaaa ggaagcttcc cggtctctag gaacatcaat agctacttca
     1561 ccaaaactgg ttttaagcgt tttagttcca tagccatttc gacggttatc gtgttcctta
     1621 ggctctttag aatgggcatc ataacctaaa tgattattca attctccttg aagcattttt
     1681 tcaaaaaggg gcccaaacac atctttcaaa gcatcttgca tgtcatcgac agattcaggt
     1741 tgataggcat tcagaatgga ttcagctaac ttttcggcat caggatttct tttctttcta
     1801 gccatcgtgt aatcacctct tgatcttatt gtagaaaaag aaaaaccgcg aagcaaccac
     1861 ctgcctagga ttaatggtta cttacacggt ttatattaca ctctcatcat taaaaaagta
     1921 tctttcgata ttactaaaca atgaaattat ctatttgaaa tttaaatctg ataatatatt
     1981 gagtgttcca atgagggctt tgatcctatt atccatatct ttttcagttt taatattgat
     2041 acacattata agaaaaagaa acttttggtt aatttatttc atcccagtgc aaaatataaa
     2101 aaagtaaaat agaccatagg caatagatta acaattaata taatacaagc aaatattcta
     2161 ttcattgtat ttctgctttc aaaaagttct aatattgaaa gtataattcc acaaatgcct
     2221 ataataagta tgggaataag attagaaaat aacaccccga gccaatctgt gaaaattact
     2281 atatttacta atatccctat taacatacct atcatattta ttaaatcaat ttttttcatt
     2341 agatatttct cctttattaa atctgaagta cttatattaa aataattcta aactatttac
     2401 ctcaaaaagt gcaataaatt atttctgaac aataaaatga tagtcaaaac aaaaaaatat
     2461 tgttaatcgt tcagagccat ccgagagt
//
LOCUS       DAFBVQ010000142         2483 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.148, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000142 DAFBVQ010000000
VERSION     DAFBVQ010000142.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2483)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2483)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2483
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.148"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(1014..1304)
                     /locus_tag="LLC22_002853"
     CDS             complement(1014..1304)
                     /locus_tag="LLC22_002853"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002295437.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436045.1"
                     /translation="MEKKYGTVDKIRTLQVSARPLIRFSLNGVNCLIASHSLNFLAEV
                     DEGMKLVVTGYYNNRKQFVVRSYHVLGKPKIVVEYEKSLYPRKKVRQDERIN"
     gene            complement(1512..2203)
                     /locus_tag="LLC22_002854"
                     /pseudo
     CDS             complement(1512..2203)
                     /locus_tag="LLC22_002854"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318394.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA-directed RNA polymerase subunit omega"
BASE COUNT          734 a          458 c          348 g          943 t
ORIGIN      
        1 atacttgcaa agtaatacta caattcctaa cataatcgta gaatttaata atttccatag
       61 cataaagtgt ttagaaaaga acattaagaa tagttctata ataattcttg aactccatgt
      121 cttataatgt tctatcgaag cacccaaata gccaagttca tctaatctac ttgcataaac
      181 tacgtcatcc gctctcatag tcggcatata catattaaag agtaaaaaga taccccaaat
      241 ccctattagt aacaagatca gttctttgtt attcgttatt tttctattat gtttgttcat
      301 ttttatactc cttcttatat ttcctaatag agtataacat agctttaagc attacttaaa
      361 gataacttaa aagttatctt ttaaatactt aattgttaaa taccttattt gatgcaaaag
      421 aaatctacga tagtcaacaa aaaaattttc attatatcca gaaaaatttt tcttagttaa
      481 ggacctatgg attgcagtaa tgcagaattc gtcgaataaa ctgccaaaga catacaatca
      541 tattgctttt aaaattgacg aacaagatat agattcgttt gtctcaaaaa tccaaatgtt
      601 aggtttaact gtcgaaccag gacgttctcg tgtgaaaggc gaggcttctt caatttactt
      661 ttacgactat gataatcacc tcttcgagtt acataccggt actctccagg aacgtttaaa
      721 atcctacaat tccactacct gagactagta atgactagtc tctttttatg gcctctgatc
      781 cccccattga gcgaatacta atagggcttc gaattgatct gttcaatctt taagcaatat
      841 ccctcaaatg agtttggaaa gtttagtgat tcatcacaaa tacttaaata catgtagtta
      901 tatatagatt gaggttcttg tgagcgtatg ctcgtgtggg ttcaaatccc atcgtctgca
      961 tccatctttc caaaacaagc ggctaggaca tttttgtctc agccgcttgt tttctagttt
     1021 attctttcat cttgtcggac cttttttctt gggtatagac ttttctcata ttctaccaca
     1081 attttgggtt tccctaacac atgataggat ctcacaacaa attgctttct attattataa
     1141 taacctgtaa cgactaactt catcccttcg tctacttcag ctaggaagtt caaactatgg
     1201 gaagcaatca aacaattgac cccatttaaa ctgaaacgga tcaacggtct ggcactaact
     1261 tgcaaagtac ggatcttatc tactgttcca tattttttct ccataacctt cacctcaata
     1321 ccattatacg aacatacatt ccctttgtaa agaagaaact ctgttttatc tttttgactt
     1381 tttgtctatt acctttctta aaatcatatt ggcacttcct gcgaagatga aggacatgta
     1441 ctaaaaaaaa gaggcagcag tatagattac tgttgcttct ttactaattt aggtttactt
     1501 gttaagaaag attatttacg caaatgttct tcaacaattt gctgagattt atcagctgta
     1561 tcttccactt catcttttgc tttttctaac ttttgaatat attgtttcaa gcttgagttt
     1621 tcagcagttg cttcgtctaa tttcttttgt gtatctgtta actgatttct acatttgttt
     1681 tttcttgtgt cagtgttgcg atttgttgat tcaaaccatt tacagtattt tgtaattctg
     1741 aaagttttgc ttgtgcttct tgtagtcttg ctgtccaatc tgcattcaga tgattgattt
     1801 catcattttt ttggttgatc tcatctagtt tgacattgat ttcattttgt ttgctttgta
     1861 gttgtgcatc cttgctgact aattgacttt ctaagttttg tttttctgct gccgattgat
     1921 ttttttggtt ttctaattca tttacttttg tttggtattc ttggacatct gcctttgaat
     1981 cttgcaatgt ctgttctttt tgtgctagtc gagcggtaag atctgtaatc gcttgctctt
     2041 tatctgtcaa tgtatgatca agctgtgtca gattctcatt gattgtatca atatctgtct
     2101 ctccacccca caaaataatt tcatttgcgt accgcgtgcc tgtgtagcca attagacata
     2161 gaaatgcaac gacaatccca ccagtaataa atttcttttt catttgcata gctccttaat
     2221 ccaatacttt tacatgctaa aagtaagtga tctcaaacac aatgtcaagc gtttttaaat
     2281 tacatatgta attttaatat aaatactatc aaatactcat ttaatcctcc ttttttatct
     2341 atttaaaaaa tcttttttat agagaaaaat gcaggttaat actttcttaa ataaatattt
     2401 atggtgaaca aaaacaaaaa agcaagtttt attaaacgta acccttttca tttcatagat
     2461 tactgtattt attacaaaaa acg
//
LOCUS       DAFBVQ010000143         2397 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.149, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000143 DAFBVQ010000000
VERSION     DAFBVQ010000143.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2397)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2397)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2397
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.149"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            206..2068
                     /locus_tag="LLC22_002855"
     CDS             206..2068
                     /locus_tag="LLC22_002855"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5436046.1"
                     /translation="MQQLTKRERQLLIYLVEMSEPVTIKKLAEKENVSVRTIKYDLDD
                     IREWLNERKQVLYSKRSQGIWMNISSSDRIKLKSELMDVNRFEIFADQSLRIKRLLIM
                     LLVTKEAITGMKMANALDVSKDTIMNDLDVLENNFLKEGLTLNRQARKGFWIIGEERL
                     VRLTIEEILQKEFTDYDIYKLMSLLLNGGETEYFEMYSATATPIQEVFNQVIIRMRHL
                     LEFENLEKLNYAELLNILIRVTIATVRLRKEATIGRYQLVAEQELDKNDLSYRVMQQV
                     FDYYQLPLFEDEYHYIYSDTFDTIHQQDVMKLVENVIYKVSKAINHSFYQDPQLLTNL
                     YAHLSMRLSRKKKFVNEYNPFKEDIKQKYPELFDAIKQAVRQEISEQNILINDSFVAY
                     IALHFLVSYEREEDLRSVRAVYICSTGLGVTSLIKQKINEELNNITIVAFASVLNAQE
                     MIATKDPDLVISIFPINGIDRPFIKVHPLPTEQDLKKIQQIIKKILASSNQQERHNLN
                     LRETSINKDTLEDFSKELILKAYTIYERLLVILEAELIQEYREAFLLHVFLMVHRITF
                     DQQYMAEGRQVDQIILDKGTLVGKIEAVFAENNLGINQSEISALFSYIKEGASS"
     gene            2068..>2397
                     /locus_tag="LLC22_002856"
     CDS             2068..>2397
                     /locus_tag="LLC22_002856"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306983.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5436047.1"
                     /translation="MKMSDEALKIIEESQNREKLKQVIDLIEERLVEHAIVPTELQWT
                     ILINHLNEMLKRSQRKETIPVVDRDLFKEVSKEAITISDEIVRSIGNLTDDEIYVLSI
                     HFETAKNN"
BASE COUNT          864 a          353 c          466 g          714 t
ORIGIN      
        1 aaaatttgaa aaagcgtttg attatttata ttacgactta gtgcaataaa aaacgctttt
       61 taacagtaca tgtagtcgtc tttataatag ataaactctg taatattagt taaaaagcta
      121 taagttgcac ttagttaagt gcaaacattt catattgtcg ttagtttaga aaacgcttat
      181 attagcaatg taaggagaga tgataatgca gcagctaaca aaaagagaaa ggcagctttt
      241 gatttacttg gtggaaatgt ctgaaccggt aacaatcaaa aagttggctg aaaaagaaaa
      301 tgttagtgtt cggacgataa aatacgatct agatgatata agagagtggc tgaatgagcg
      361 gaagcaagtc ctatatagca aacgtagtca gggaatttgg atgaatatta gtagctctga
      421 tcgaatcaaa ttaaaaagcg aattgatgga tgttaatcgt tttgaaatat ttgcagatca
      481 aagtctccga atcaaacgtt tactaattat gcttttagta acaaaagaag ctattactgg
      541 aatgaaaatg gccaacgcat tagatgtcag caaagatacg atcatgaatg atttagatgt
      601 gctggaaaat aattttctta aggaaggatt gaccttgaat cgtcaggcgc gaaagggttt
      661 ttggatcata ggagaagaac gtctagttcg attaacgatt gaagagattc ttcaaaaaga
      721 gttcacggat tatgacattt ataaattaat gtcattgtta ttgaatggcg gtgagactga
      781 atactttgaa atgtattctg ctactgctac acctatccaa gaggtattta atcaagtaat
      841 cattcgaatg cgacacttac tggaatttga aaatctagag aaactgaatt acgcggaatt
      901 actaaatatt ctgattcgag tgacaattgc taccgttcgc ttacgcaaag aggctacgat
      961 tggtcgttat caattggttg ctgaacaaga attagacaaa aacgatcttt cttatcgcgt
     1021 catgcagcag gtctttgatt attatcagtt gccactgttc gaggatgaat atcattatat
     1081 ctatagtgat acattcgaca cgattcacca gcaagacgtc atgaaactag ttgagaatgt
     1141 gatttataaa gtaagtaaag caatcaacca ttctttttat caagatccac aattgttgac
     1201 gaatctgtat gctcatttat ccatgcgatt atcgagaaag aaaaaatttg tcaatgaata
     1261 taatcctttt aaagaagata tcaagcagaa atacccggaa ttatttgatg cgatcaagca
     1321 agcagttcga caagaaataa gtgaacaaaa tattctgatc aatgattctt tcgtggcata
     1381 tattgcctta cactttttgg tttcctacga aagagaagaa gatctacgaa gcgttagagc
     1441 cgtctacatt tgttcaacag ggttgggtgt gactagtctg atcaagcaaa agatcaatga
     1501 agaattaaat aatatcacta tcgtggcatt tgcttcagta ttgaatgcgc aagaaatgat
     1561 tgctaccaaa gatcctgatt tggtgattag tatttttcca attaatggca tcgatcgtcc
     1621 tttcatcaaa gtccatccat tacccactga acaggacttg aaaaaaattc aacaaataat
     1681 aaaaaaaata cttgcttctt ccaatcagca ggaaaggcat aacttgaatc ttagagaaac
     1741 gtccatcaat aaagatactt tagaagactt tagcaaggaa ttgattttga aagcttatac
     1801 gatttatgaa cgtttacttg tcattttgga agcagaattg atccaagaat atcgagaagc
     1861 ttttttgctt catgtattct taatggttca tcgtatcaca tttgatcaac aatatatggc
     1921 agaaggtcgt caagtagacc agattatttt agacaaagga acactggtag gaaaaatcga
     1981 agcagttttt gcagaaaata atttaggaat caatcagtca gaaatcagtg cattattctc
     2041 atatataaaa gaaggagcgt caagttagtg aaaatgtcag acgaggcttt aaaaattatc
     2101 gaggaaagtc aaaatcggga aaagttaaaa caagtgattg atctaattga agagcgatta
     2161 gtagaacatg ctattgtacc aaccgagttg cagtggacca ttctaattaa tcacttgaat
     2221 gagatgctga aacgttctca aagaaaggaa acgattcccg tagtcgatcg ggatttgttc
     2281 aaagaagtat ccaaagaagc cataactatt tctgatgaaa tagttagaag tatcggtaat
     2341 ttaaccgatg atgaaatata tgttttgtcg attcattttg aaacagcaaa aaataat
//
LOCUS       DAFBVQ010000144         2395 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.150, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000144 DAFBVQ010000000
VERSION     DAFBVQ010000144.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2395)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2395)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2395
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.150"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..956
                     /locus_tag="LLC22_002857"
     CDS             <1..956
                     /locus_tag="LLC22_002857"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS256-like element IS256 family transposase"
                     /protein_id="HBK5436048.1"
                     /translation="GTLELKVPRTRDGHFSPTVFERYQRNEKALMASMLEMYVSGVST
                     RKVSKIVEELCGKSVSKSFVSSLTEQLEPMVNEWQNRLLSEKNYPYLMTDVLYIKVRE
                     ENRVLSKSCHIAIGITKDGDREIIGFMIQSGESEETWTTFFEYLKERGLQGTELVISD
                     AHKGLVSAIRKSFTNVSWQRCQVHFLRNIFTTIPKKNSKSFREAVKGIFKFTDINLAR
                     EAKNRLIHDYIDQPKYSKACASLDDGFEDAFQYTVQGNSHNRLKSTNLIERLNQEVRR
                     REKIIRIFPNQTSANRLIGAVLMDLHDEWIYSSRKYINFDK"
     gene            complement(1086..>2395)
                     /locus_tag="LLC22_002858"
     CDS             complement(1086..>2395)
                     /locus_tag="LLC22_002858"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBK5436049.1"
                     /translation="SLKKHYTEPWEDEVFRVIIEYNNVPIGYGQIYKMYDELYTDYHY
                     PKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAVILDPHKNNPRAIR
                     AYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKYLIEHYFDNFKVDS
                     IEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNTNLETNVKIPNIEY
                     SYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLRQMHGLDYTDISEC
                     TIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFEGKKCLCHNDFSCN
                     HLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGEDILRMYGNIDIEK
                     AKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
BASE COUNT          813 a          424 c          287 g          871 t
ORIGIN      
        1 taggcacgct agaattaaaa gtacccagaa cacgtgatgg ccatttttca cccacagtgt
       61 ttgaacgtta tcaacgaaac gaaaaagccc tcatggcttc aatgttggaa atgtatgtat
      121 caggcgtttc aactcgtaaa gtatcaaaaa ttgtggaaga actttgtggt aaatccgtct
      181 ctaagtcctt cgtttctagc ttaacagaac agctagaacc tatggttaac gagtggcaga
      241 atcgtttatt atcagaaaaa aattatcctt acttaatgac cgatgtactc tatataaaag
      301 tacgagaaga aaatcgagta ctctcaaaaa gctgtcatat agcgattgga ataaccaaag
      361 atggcgaccg tgaaattatc ggcttcatga ttcaaagtgg cgaaagcgaa gagacctgga
      421 caacattttt tgaataccta aaagaacgcg gtttacaagg tacggaactc gttatttctg
      481 atgcgcacaa aggattagtc tctgccatta gaaaatcctt caccaacgta agttggcaaa
      541 gatgccaagt tcacttccta agaaatatct ttaccaccat tcctaaaaaa aattcaaaat
      601 ctttcagaga agctgttaaa ggaattttta agttcacaga tattaactta gcgcgtgagg
      661 ctaaaaatcg attgattcat gattatatcg atcaaccaaa atattcaaaa gcttgcgcat
      721 cattggatga tggattcgaa gacgcctttc aatataccgt acaaggaaat tcccacaatc
      781 gactaaagag taccaatcta attgaacgac tgaatcaaga agtacgcaga agagaaaaga
      841 ttattcgcat cttccccaat caaacatcag ccaatcgctt aattggagcc gttcttatgg
      901 acctacatga tgaatggatt tattcttcaa gaaaatacat caattttgat aagtagaaat
      961 ggtaaaaaca ttgtatagca ttttacacag gagtctggac ttgactcact tcctttatta
     1021 tttttcattt ttttaaacta tttaatacta atgtctttta taatagcttt tcatatatta
     1081 tataatcaat ctttataagt ccttttataa atttcttttc taccattttc gataaattcc
     1141 tgtttaatat ttttaattcc ataaacaata gtttcaatag gataatattc ttcaactata
     1201 tcttgatatt cttttgcttt ctcaatatct atatttccat acattcttaa tatatcttct
     1261 ccaaaatttg ttcctatttc ttcttcacta tcttcaagta agtatataaa atcacaatat
     1321 tcatctataa ttccagaatc tccaaaatca attattccag ttaatctatt attgccatct
     1381 aacaatagat gattacaact aaaatcatta tggcataaac actttttacc ctcaaaaact
     1441 gttgttgcat ttagtctttc cataaaactt tctatataat ctttttctat atcagttaaa
     1501 tcattataaa tagtttcacg caacaatata tactcttcta atacattttg tttattatca
     1561 atagtacatt cactaatatc tgtataatct aaaccgtgca tttgtcttaa aaaactggca
     1621 atatctcgtt ttaacaaatt ttgttcttct tctgacatag tagaataaat ttctggtgtt
     1681 aaaaaagttc ctttaatttc tttataacct agtatagata attcatcact aatatacgaa
     1741 tattcaatat taggaatttt tacattagtt tctaaatttg tatttaaaaa attatatatt
     1801 gctttttctt ttgcataacc ttttttctta ttagtactaa attttgtttt aaaaatgtat
     1861 tcattattaa ctaaatatgc cacactatca taaccactac cgattatttc aatactatct
     1921 actttgaaat tatcaaagta atgctcaatt aaatatttca ttgccttaac atttgtggca
     1981 ttatcatcat atctatattc cattaaataa caatcttctt ttttgccctc gtgtaattca
     2041 tgttctggca aatcttcaat aattctaaaa ccagattttt ggtatgccct tattgctctt
     2101 ggattatttt tatgagggtc taaaataact gcattagcat ttctttcttt tttcaaaaat
     2161 tcaaaaatca atttaatata tcttgtacca attcctttac tccaataatt tggctctcct
     2221 ataaattgat ccataccata gactatctca tcagtttttg gataatgata atcagtatat
     2281 aactcatcat acattttata tatttgtcca tatccaatag gaacattgtt atattcaata
     2341 attactctaa aaacttcatc ttcccaaggc tctgtataat gtttttttaa tgatt
//
LOCUS       DAFBVQ010000145         2306 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.151, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000145 DAFBVQ010000000
VERSION     DAFBVQ010000145.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2306)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2306)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2306
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.151"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..544
                     /locus_tag="LLC22_002859"
     CDS             <1..544
                     /locus_tag="LLC22_002859"
                     /inference="COORDINATES: protein motif:HMM:NF033516.0"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS3 family transposase"
                     /protein_id="HBK5436050.1"
                     /translation="ISKENLLNQDFSTETICEKWAADITYIPTKKNGWCYLSSIMDLH
                     TKRIISYTFSKRMTVDCVIQTLNKAKIHYHIPEGMILHTDLGSQYTAREVEQWLKTNK
                     IRHSYSRKGTPYDNAGIESFHASLKKEEVYTTSYSDFEEANRALFSYIEGFYNRNRIH
                     SSIHYLTPQEFEELAKEKMA"
     gene            complement(1017..1589)
                     /locus_tag="LLC22_002860"
     CDS             complement(1017..1589)
                     /locus_tag="LLC22_002860"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000170424.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="recombinase family protein"
                     /protein_id="HBK5436051.1"
                     /translation="MTKYGYARVSTASQSTKEQIQQLLENGVEKKNIFSEKFTGTKRD
                     RPKFNQLLAGLKPGDEIVVTKLDRFARNTREALEIIEPLLDDNVTIKVLNLGTIENTS
                     MGRMVTRTLLSVAEMERDMIVERTQEGKMFARKNNPNFREGRPKATITPKKRHAYELL
                     TSGKSYKEVEAITGFSRSTLFRIKKKIEES"
     gene            complement(1605..2210)
                     /locus_tag="LLC22_002861"
     CDS             complement(1605..2210)
                     /locus_tag="LLC22_002861"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016176895.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cell filamentation protein"
                     /protein_id="HBK5436052.1"
                     /translation="MILENKLGLTNQVELAKVEEKLSKQKAKELYDCGKINEIEVGTF
                     KGLSEIHEFLFSDIYDFAGKIRSVNIAKGNFRFAPVMYLEHSLQHIDQMPQTSFEEII
                     KKYVEMNIAHPFREGNGRSTRIWLDLILKEELQKVVDWNLIDKADYLSAMERSPINDL
                     EIRYLISNALTDKIDDRELYMKGIDVSYFYEGYSEYTIDDL"
BASE COUNT          730 a          458 c          351 g          767 t
ORIGIN      
        1 catttcaaaa gagaatctct taaatcagga cttttctact gaaacgatct gtgagaaatg
       61 ggcagctgac attacgtaca ttcctactaa gaaaaatggt tggtgttact tatcttcaat
      121 catggattta cacacgaaaa gaattattag ttatacattt tcaaaacgaa tgactgtgga
      181 ttgtgtcatt caaacattga ataaagcaaa aatacattat cacattccag aaggaatgat
      241 tctacacact gacttgggca gccaatacac agcaagagaa gtggaacaat ggcttaaaac
      301 caacaaaata aggcattctt atagtagaaa aggaacacct tatgataatg ctggaatcga
      361 atctttccat gcctcattga aaaaagaaga agtctacacg actagctact cagattttga
      421 agaagcaaat cgagcgctat ttagctacat tgaaggattt tataaccgaa atcgaatcca
      481 tagctcgatt cactatctaa ccccacagga atttgaagaa ttagcaaaag aaaaaatggc
      541 ttaaccgtct ctactaaaat gtgtccaaga tattgactca aatccagtaa tatcacaata
      601 ggaatgctgt ttattatatt agcagcagtg ctgattttta tgatagttat ttggttctta
      661 aatgaaagat ctaaagacaa tcaacaccgt agggatatgg agataaaatc aatagagtca
      721 atagattatt tatcgataat aacactaaaa aagccacgtt cctaaacgtg acttacgctg
      781 aacgatatgt gttgtttggt agacgaacaa atcgttcatt ataaatatat gatggtatcc
      841 taatatagta agcgtggcta gcataccttt aattacttta ccttttacag ttaccataca
      901 cattttttga gcagaaatca agtaaataaa aaaatattat atttcacaac atgctaatag
      961 actcatatct agaacgcatt aagtatttac ctgtctggtt cgctgagact tcttttttaa
     1021 ctttcttcaa ttttcttctt tattctaaaa agcgtactgc gactgaaacc ggttatagct
     1081 tcaacttcct tatacgattt acctgaagta agcagttcat atgcgtgcct cttcttcggt
     1141 gtgattgttg ctttcggacg tccttctctg aaattaggat tattctttct tgcaaacatt
     1201 tttccttctt gggtacgttc cacaatcata tcacgttcca tttctgctac actcaacaac
     1261 gtccgtgtca ccattcgccc catggacgta ttttcaatcg ttcctagatt caaaaccttg
     1321 atcgttacgt tatcatcgag taaaggttca atgatctcta atgcttctct cgtgttacga
     1381 gcaaatcgat caagcttcgt aacaactatt tcatctccag gcttcagacc agccaacagc
     1441 tgattgaatt ttggccgatc ccgttttgta cccgtaaatt tttctgaaaa aatattcttc
     1501 ttctctacgc cgttctcaag caactgttga atttgttctt ttgtactttg agaagcggtt
     1561 gagacacgtg catatccata tttcgtcatt tggtccacct acttttacaa atcatctatc
     1621 gtatactcag aatacccttc atagaaatag ctgacatcga ttcctttcat atataactcg
     1681 cgatcgtcaa ttttatcagt cagagcattg gaaattagat agcgtatttc caaatcgttt
     1741 atgggacttc gctccattgc agaaagatag tctgctttat cgattaagtt ccaatctaca
     1801 actttttgca attcttcctt taaaatgaga tccagccaaa ttctagtact tcggccattt
     1861 ccttctcgaa atgggtgagc gatattcatc tccacatatt tcttgataat ctcttcaaaa
     1921 gaagtttgtg gcatctgatc aatatgctgt aacgaatgtt ctaaatacat aactggtgca
     1981 aatcgaaaat ttccttttgc aatattgacc gatcggattt ttccggcaaa atcgtaaata
     2041 tccgaaaata gaaattcatg aatttcagat aaacctttaa atgtaccaac ttcgatttca
     2101 tttatttttc cacaatcgta caattctttc gctttttgtt tactgagttt ttcttcaacc
     2161 ttagccaact caacttgatt ggttaatccc aatttattct ctaaaatcat gcgaaatctc
     2221 cttaacttta tgacataagt ttatgaaaca ctctcaaccc cattatatcg cgattttgtt
     2281 tatgtgtcaa aaactattaa gtttct
//
LOCUS       DAFBVQ010000146         2288 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.152, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000146 DAFBVQ010000000
VERSION     DAFBVQ010000146.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.152"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            1172..1726
                     /locus_tag="LLC22_002862"
     CDS             1172..1726
                     /locus_tag="LLC22_002862"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303574.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5436053.1"
                     /translation="MSYNVQPLRTNEEIQDFQFWLRRTSNPERDSFLFLFGINNGLRM
                     SDIIGLKVGDIRGKSKPIIVEHKTGKRKPIFIDNLREEILLYTEGKEENDWLFPSRQQ
                     GRHITRDRVYQIYADIAEKLGRDDIGTHTLRKTFGYHYYKKTRDIATLMFIFNHSSQA
                     ITKRYIGITEDEIGASLRGFKLGG"
     gene            1980..>2288
                     /locus_tag="LLC22_002863"
     CDS             1980..>2288
                     /locus_tag="LLC22_002863"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305121.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436054.1"
                     /translation="MINSAYFHIKYLKKYEYEEVVLDYGLNRQSFLIYAINNGNLPSN
                     KKNIIIETYAYLEGGSKKLIKSCNIEYQLSVGEIKCVFEEDLELDLKKIFASIHDYIG
                     L"
BASE COUNT          887 a          253 c          354 g          794 t
ORIGIN      
        1 gaaaacgtag acgtaatttt ctacgttttc cttttcatat atattaaata ttacggaaat
       61 ttatataaac taatttagtg ttttgtttgt aattcctaat tttgctccac ttttagataa
      121 tttttaggtc tatttaactc atcagacatt ctatgctcat tttctccaaa tttgtttcaa
      181 ctctttcgta cttaattttg cgtatttgaa aattcttctt ttagagtact tttattacga
      241 tactagtatg atatatatct atagcaaaca gttaaaatct tcctaaaata agcgaatagc
      301 attcctaaaa cctataaaat ttttagatga agcgacaagt ggacaattaa taaactactt
      361 gaacatgaaa ttatggatca cctttcaaat ttagaaaatg gaattcttat acttattgcg
      421 caacatttat tgattgcaaa attatgtgac aaaaagaact agtagaagaa ggaataatgg
      481 cttgataata aagtactacc tattaaaggt agtactttat ttaatttagt ataaattaac
      541 atactactat attttaagtt tcatattata taaattaata atatactacc attttttggt
      601 agtataattt aaaggtaata agttattctt ttattactat gtttgggttt tatagcaagg
      661 aaagtttaat aagagtttgg acctagcaaa caatattaat gaggtcatta aatcttatta
      721 tctttagtga tataacgaaa tatctacaca gacaaaatta tgatcttgcg taaagttata
      781 aaatattaat aaaaatattt tattaatgaa aagcttggta gcacggttat tcatatgcta
      841 atttatttca ctttatagta aggggagttc ttagtatatt gtccaaattt aaatttcata
      901 taatttaatt atgtaaatta gctattctaa gaacttctac ggataactgc ccgtctaaaa
      961 tttaattaag agcttagaat cttcatataa gtaaggttaa tttttttgta caaaatagtc
     1021 ggaatattct gagttactga aatgatataa aatcataaac taaacccctt gattttcttc
     1081 acttttaaca gagtatatat ataagttcat gattatggta aaatatatat ataatcatga
     1141 actcagaata tttttaagaa gggaaacaat agtgagctat aatgtacaac cgttaaggac
     1201 aaatgaagag atacaagatt ttcagttttg gctaagaaga acaagtaatc cagaaagaga
     1261 tagtttttta tttttgtttg gaatcaataa tgggttacgt atgtcagata ttataggatt
     1321 aaaagttgga gacatacgag gtaaaagtaa gcctattatt gttgaacata aaacaggtaa
     1381 gcgaaaaccg atttttatag ataatttgag agaagagatt ttattatata ctgaaggtaa
     1441 agaagaaaat gattggttat ttccaagtcg gcaacaaggt cgacatataa caagggatcg
     1501 tgtctatcag atatatgcag atatagcaga aaaattagga agagatgata taggaacaca
     1561 tacattaaga aaaacttttg ggtatcacta ctacaagaaa actagagaca ttgctacctt
     1621 aatgtttatt tttaatcata gctcgcaagc aattacaaaa aggtacattg gtataactga
     1681 agatgaaata ggggcatcgt tacgtggttt taaattggga ggctaattga gatattagga
     1741 tatatttttt gtgtataatg aaaacttaga aggtgagatt aatgaagata actgaatttt
     1801 cggaagtatt taaaacgttt agtaacattt acaatagaat accagagata gaacaaaatg
     1861 ttgtagttga taatgattat tatatagaga atgattttaa taaaccaaga aaatatgaca
     1921 acctatacaa ttttatacac aatagaacaa caataaataa caacagtaac actcgagttt
     1981 tgattaattc agcatatttt catattaaat atttaaagaa atatgagtat gaagaagttg
     2041 tattagatta tgggctaaat agacagtcat ttttaattta tgcaataaat aacggaaatt
     2101 tgccaagcaa taaaaagaac ataattattg aaacatatgc ctatctggag gggggatcta
     2161 aaaaactaat taagtcatgt aatatagagt atcaattatc agtaggagaa attaaatgtg
     2221 ttttcgaaga agatttagaa cttgacttaa aaaaaatttt tgccagcatt catgattata
     2281 taggtttg
//
LOCUS       DAFBVQ010000147         2104 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.153, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000147 DAFBVQ010000000
VERSION     DAFBVQ010000147.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 2104)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2104)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..2104
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.153"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            169..1539
                     /locus_tag="LLC22_002864"
     CDS             169..1539
                     /locus_tag="LLC22_002864"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324486.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4357 domain-containing protein"
                     /protein_id="HBK5436055.1"
                     /translation="MMDKSNEEQTTLYTKYWRRLEEVFDNSKGMEDFFRYYLAAITGE
                     YSAKHILYQAFKDYWHKERDVSSDAELLQKLVRYAGYFARLYYNKPEGKYSEVLSDFQ
                     SMESMMPAPFVLGLSEWYYHDQFITEDQYIDAIKVVNDYQLRRYFNGDDTSRVSKAFP
                     SYLKSVRKYAKANGYENIVDIVIYVLVTRNQSNNMALPSDKALKSNLLNANAYAMRLA
                     RWLLEKIENRENSATLDMSNLSIEHIMPQTSTSYWEEKAGTSGEEYTGLVNTIGNLTL
                     VTNPDNSAAGNKDFETKKKIFEDTLHIRMNKDLYELTEWTSSDISARSEALINELITM
                     YPYLRSSGDYEHDGNREIFLEAQGIKATGYLNEDETVIIHSGSEIYSKIKDIASDSLD
                     ETRQELLDNGIIEETIGGLQFVQDYTASSVSNAAALLLGGSRNGWDYWKYDNGISIND
                     SLRNKK"
     gene            1560..1844
                     /locus_tag="LLC22_002865"
     CDS             1560..1844
                     /locus_tag="LLC22_002865"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436056.1"
                     /translation="MDKNKLRYAILKLRDEKKNPFIELKGQVPEEDILEQTKFLSRNG
                     LLESMVWADNTVHIWGSVSLEGEKYLVENSGLAKAYALAKEVKNWIPFWG"
BASE COUNT          731 a          308 c          444 g          621 t
ORIGIN      
        1 ttgatttacc aacatgttta gacattttcc tctaggaaaa aattaactag caccacgcgt
       61 attgtttata ttaaattaga tgaccgtgat aatgcacagc aaatttttga aagtatcaat
      121 tctaccggtg aaagattgac tgcctcggat ttgattcgaa acttcatcat gatggataaa
      181 tctaatgaag agcagactac gctttatact aaatattggc gtaggttgga agaagtcttt
      241 gataattcta aaggaatgga agactttttc agatactacc ttgctgcaat aactggggag
      301 tattcagcaa agcatattct ttatcaagca ttcaaagact attggcataa agagcgcgat
      361 gtatcaagtg atgccgaatt gctccaaaaa ttagtgcgat atgctggtta ttttgcgaga
      421 ctttactata acaaacctga aggaaaatac tcagaagtat tgagcgattt ccaaagtatg
      481 gaaagtatga tgcctgcacc ttttgttttg ggattatctg aatggtacta tcatgaccaa
      541 tttatcactg aagaccaata tattgatgcg attaaggtag tgaatgatta tcagcttagg
      601 agatatttta atggggatga tacaagcaga gtgtcaaaag catttccttc atatttgaaa
      661 agtgttagga agtacgctaa agctaatgga tatgaaaata tcgttgatat tgtaatttat
      721 gttcttgtta ctagaaatca atcaaataat atggcacttc catctgacaa ggcattgaaa
      781 tctaatctat tgaatgccaa tgcttatgcg atgagattgg cccgttggtt acttgaaaaa
      841 atagagaatc gagaaaattc agcaacactt gatatgagta acttgtccat tgaacacatc
      901 atgccacaga ctagtacttc atattgggaa gagaaggctg gtacatcggg ggaagaatac
      961 acaggattag taaataccat tggtaattta acactcgtta caaatcctga taattcggcc
     1021 gcgggaaata aagactttga gaccaaaaag aaaatctttg aagataccct tcatattcgt
     1081 atgaataaag atttgtacga attgactgag tggacatcat cggatatttc tgccagaagt
     1141 gaagctctaa tcaatgaact gattactatg tatccctatt tgagatcgtc gggcgactat
     1201 gaacacgatg ggaataggga aattttctta gaggcgcaag gaataaaagc aactgggtat
     1261 ttgaacgaag acgagaccgt gattatacat tcaggttcag aaatttattc taagattaaa
     1321 gatattgcat ctgattcgct agatgaaact cgccaagagc tgttggataa tggaatcatt
     1381 gaagaaacaa ttgggggact acaatttgtt caagattaca ctgcctcatc tgtttcgaat
     1441 gcagcagctc tgctattagg gggtagccgg aatggttggg actactggaa atatgataac
     1501 ggaataagta ttaatgattc gctaagaaat aagaaataga gcatagaggt ggtgttaggt
     1561 tggataagaa caaactaaga tatgcaattc ttaaattgcg tgatgaaaaa aagaatcctt
     1621 ttattgagct taaagggcaa gttccagaag aagatatttt agaacaaact aaatttcttt
     1681 cgcgcaatgg cttactagaa tccatggttt gggcggataa cactgttcat atctggggga
     1741 gtgtttctct ggaaggggaa aaatatttag ttgaaaactc aggtcttgct aaggcgtatg
     1801 cattggcaaa agaagttaaa aattggattc cattttgggg ctaagataag tttttaaacg
     1861 gagaaggtag caaatcataa ttggtttgtt gccttttttg attgcccaaa aagaaaaatg
     1921 acaaagtata gagataaatg acatagtaca cgggaaaaat gacattgtat caccgacaac
     1981 gtctaaatag atgttgatat atatacgttc cgtacaaata attataaaaa tttaaatgat
     2041 ttgagtagaa gtatcagtga atatctcaag gggaatagct atctcaagat tcgattttca
     2101 cata
//
LOCUS       DAFBVQ010000148         1980 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.154, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000148 DAFBVQ010000000
VERSION     DAFBVQ010000148.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1980)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1980)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1980
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.154"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(325..529)
                     /locus_tag="LLC22_002866"
                     /pseudo
     CDS             complement(325..529)
                     /locus_tag="LLC22_002866"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002352749.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            complement(729..1745)
                     /locus_tag="LLC22_002867"
     CDS             complement(729..1745)
                     /locus_tag="LLC22_002867"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299382.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication protein"
                     /protein_id="HBK5436057.1"
                     /translation="MANENQLSEIQSKIEGRGAEKRTTINQLEKLNRISNRRLSVQGT
                     TTPLKLNWSIDRITIVGKLNDTIAYWTKNGVVFVDFEQLMRLNENQGYLKSVGINGWQ
                     LFDQYGEDIAYIEILKFHEGKGRIDFNPNKIGQFLASSMKGFIHDLFLDPHFSRADIA
                     CDIVDVPDDFITQYRIVDPISFKPIYGRSGKLETAYWGSRASERQVRLYNKKLEQERK
                     KVIVPKEIDTWWRLEMQLRRGKATDWHAMVQESLDSFASPHFLPIDIKPIDKIVIDGL
                     IAEPSNWSIIARHTKYKYRNLLKQESQNDELTNHLRETFKESADELKKELDTWLLGLD
                     VTEK"
BASE COUNT          558 a          459 c          309 g          654 t
ORIGIN      
        1 aaaaaaataa aaagacctca gggaatttca ttccccgaac cccttgagcc tcctcctgcc
       61 gaaatggaaa gggcgcaccc gctgtttatt tcattcagct atcggttttc acaatctaac
      121 acgatcgttc cgctaccagt cgccttacag gctccatttt cgctcctcta acgtgtttta
      181 acgattgtgc cgataactaa acgaaataaa cgctaaaacc gctcagaacg caaaatatgc
      241 cattttagag ctattgtaga aaatgtagtt tgaaatgcaa ttttcttctt tcagcttttt
      301 atttcccact tgtaaatctg ctaattattt tctaccagac aaaccattga ttttttggct
      361 atcagttaac tcacgattat tatgagaaat gcttgtattc tttgttccct ttttgaacga
      421 aatactaaac cctaaggtga acccctcctt cacgctgtcg ctaataaaaa gagtgtaaac
      481 ctttctgtta ctctttgaca aagagtaaaa attttcctaa ttgtgacatg gctgtcacaa
      541 ttccaaatgc tctccgaggg tattcgctgt cacaagtgac aacgaaaaaa ggagccgaaa
      601 gcgtgtcacg ctctcaactc cttttacgct ttattttgct tcatgcaaaa tattcgctta
      661 tcgtgaattt acgtcactaa acattgacgc aaatccactc tcactcatct gacttttctt
      721 attcggtatc acttctctgt cacatccaac cccaaaagcc acgtatccaa ttcttttttt
      781 aattcgtctg cagattcctt aaacgtctct cgtaaatgat tcgttaactc atcattttga
      841 ctttcttgct tcagcaaatt ccgatattta tattttgtat gtctagcaat tatcgaccaa
      901 ttagaaggct cagctatcaa accatcaata actattttat caataggttt tatatcaatc
      961 ggcaaaaaat gcgggcttgc aaaactatct aagctttcct gaaccatcgc atgccaatcc
     1021 gttgctttgc cacgtcttag ctgcatttct aaccgccacc acgtatcgat ttcttttggc
     1081 acgattactt tttttcgttc ctgctctagc tttttgttgt acagtcgcac ttggcgctca
     1141 ctggcacgac tgccccagta cgctgtttct agcttgccag aacggccgta gattggctta
     1201 aaagaaatcg ggtctacaat acgatactga gtaataaagt catccggcac atctacaata
     1261 tcgcaggcaa tatccgcccg ggaaaaatgc ggatctaaaa ataggtcatg aatgaatcct
     1321 ttcatggaac tagctaaaaa ctggcctatc ttattcggat taaaatcaat acgacctttt
     1381 ccttcatgaa atttaagtat ttcgatatac gcaatatctt ctccatattg atcgaataat
     1441 tgccagccgt ttatcccaac tgatttcaaa tatccctgat tttcgttcaa acgcattaat
     1501 tgctcgaaat cgacaaaaac aactccattt ttcgtccaat aagctatggt atcattcagt
     1561 tttccgacaa ttgtaattcg atcaatcgac caatttaatt ttaggggggt ggtcgtacct
     1621 tgcacactta accgcctgtt agaaatacgg ttaagttttt cgagctgatt tatcgttgtt
     1681 cttttttctg cccctcgacc ttcaattttt gattgaattt cactcaactg attttcattt
     1741 gccattttcg tcctccaaac gaaaaaagag acttttggaa agaatttcca gagttcacgt
     1801 aaccctaaaa attcatatcc aaaaatctct agcttgaaga aacctaaaaa tattcgtata
     1861 atgaacctga gttacggagc taggtgaagt agtttccgta aatagtcgag agtgttagcg
     1921 cactgctcgg cttttatttt gctctttttt ctcgttttct ttgattatag cactcctcct
//
LOCUS       DAFBVQ010000149         1972 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.155, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000149 DAFBVQ010000000
VERSION     DAFBVQ010000149.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1972)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1972)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1972
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.155"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(46..1365)
                     /locus_tag="LLC22_002868"
     CDS             complement(46..1365)
                     /locus_tag="LLC22_002868"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008392738.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HAMP domain-containing histidine kinase"
                     /protein_id="HBK5436058.1"
                     /translation="MKKLKIFPKMFIQIFSVLGIIIILVHSLIFFIFPKTYLETRKEK
                     IHNMANEISSNMNGKEIKYIEQTLEFYSKSSEIKVFIKEKNNKNEIQIKDNINVNLES
                     DSNSLIIEEREIKLNDGKKTNLQFVSTADMQKDAKDLSLKFLPYSLLISILFSAIISL
                     IYAKSIKNNIQEIKIVTDKMMKLDKKMSLKVSSNDEVGELKQQINDLYSTLLRTIDDL
                     EFKNKEILKLEKLKYDFFKGASHELKTPLASLKIILENMKYNIGKYKERDIYINECIE
                     IVDSLTKNISQILSVHSIENLNNDEEYLKINDTLEDILKKYEILANQKKITVNNYILD
                     ENVYIGKTALKIILSNLISNAVKYTDVNGVINIGIVNDWLYIENSYGNNKISNMDKIF
                     DVKFDLNKENSNGLGLYIVSNILNNYNIEYKVLQDEEFFIFKIKIFS"
     gene            complement(1362..>1972)
                     /locus_tag="LLC22_002869"
     CDS             complement(1362..>1972)
                     /locus_tag="LLC22_002869"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334003.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="response regulator transcription factor"
                     /protein_id="HBK5436059.1"
                     /translation="ISEYLSEFGYTVIQAKDGREALSKFNSDINLVILDIQIPFINGL
                     EVLKEIRKKSNLPILILTAFSDEEYKIDAFTNLVDGYVEKPFSLPVLKARIDSLIKKN
                     YGHLEKFEYKDLSVNFNSYTAKINGEEIDVNAKELEVLKCLLDNNGQVLTRMQIIDYV
                     WKDSEETPYDRVIDVYIKELRKKLQLDCITTIRNVGYKLERK"
BASE COUNT          659 a          291 c          155 g          867 t
ORIGIN      
        1 aataagtctc tatttttcaa taactattgc aaaattatat cttaattaag aaaatatttt
       61 tattttaaag ataaaaaatt cttcatcctg caatacttta tattctatat tgtaattatt
      121 cagaatatta cttacaatat ataaacctaa tccattacta ttttccttat ttaaatcaaa
      181 tttaacatca aatattttat ccatattcga aattttattg ttaccgtatg aattctctat
      241 atataaccaa tcattaacta tcccaatatt aattacccca tttacatcag tatattttac
      301 cgcattacta atcaaattag atagaataat ctttaaagct gtttttccta tataaacatt
      361 ctcgtctaat atataattat tgacagttat tttcttttga tttgctaata tttcatactt
      421 ttttaatatg tcttctaatg tatcatttat tttcaaatat tcttcatcat tattcaaatt
      481 ttctatagaa tgaactgata atatttgaga aatatttttt gttaaactat caacgatttc
      541 aatacattca ttaatataaa tatctctttc tttatatttt ccaatattgt atttcatgtt
      601 ttccagtatt attttaagac tagcaagagg ggttttaagt tcatgggatg cacctttaaa
      661 aaagtcatat tttaactttt ctaattttaa aatttcttta tttttaaatt ccaaatcgtc
      721 aattgttctt aataaagtag aatacaaatc attaatttgt tgttttaatt ctccaacttc
      781 atcattagag ctaactttta aactcatttt tttatcaagt ttcatcattt tatcagtaac
      841 aatttttatt tcttgtatat tattttttat tgattttgca taaattaaag aaataatagc
      901 agaaaataaa attgatatta ataaagaata tggtaaaaat ttaaggctta aatctttcgc
      961 atctttttgc atatcagctg tagaaacaaa ttgtagattt gtttttttac catcattaag
     1021 ctttatttct ctttcttcaa ttatcaaaga attactatca ctttctaaat taacatttat
     1081 attatctttg atttgtattt cattcttatt atttttttct tttatgaata cttttatttc
     1141 actactcttg gaataaaact ccaaagtttg ttctatatat tttatttctt ttccattcat
     1201 attactagaa atttcatttg ccatattatg aatcttttct tttctcgtct ccaaatatgt
     1261 tttaggaaag ataaaaaaaa ttaatgaatg aactaatata attattattc caagaacaga
     1321 aaatatttgt atgaacattt ttggaaatat ctttaatttt ttcattttct ctccaattta
     1381 tatcctacat ttcttatagt agttatacag tctaattgta atttttttct aagttctttt
     1441 atatatacat ctattactcg atcataagga gtttcttcgc tatctttcca tacataatca
     1501 ataatttgca ttcttgttaa cacttgtcca ttattatcca ataaacattt taatacttct
     1561 agttcttttg catttacatc tatttcttca ccatttattt tagctgtata gctattaaaa
     1621 ttaaccgata gatccttata ttcaaacttc tctaaatgtc cataattctt cttaattaaa
     1681 gaatctattc tagcttttaa gaccggcaat gaaaatggct tttctacata tccgtctact
     1741 aaattagtaa atgcatcaat tttatattct tcatcactaa atgcagtcaa gattagaatt
     1801 ggtaaattgc ttttctttct aatttctttc aacacttcta aaccatttat aaaaggtatc
     1861 tgaatgtcta agataaccaa atttatatcg ctattaaatt ttgacaaggc ttctcttcca
     1921 tctttagctt gaataacagt atatccaaat tctgaaagat attcacttat tc
//
LOCUS       DAFBVQ010000150         1887 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.156, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000150 DAFBVQ010000000
VERSION     DAFBVQ010000150.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1887)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1887)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1887
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.156"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            612..1424
                     /locus_tag="LLC22_002870"
     CDS             612..1424
                     /locus_tag="LLC22_002870"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002317378.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436060.1"
                     /translation="MILLAVSMSLLIYTHILSTFMSVIVIGFLFIGSLFSKRKERKEM
                     SNLISNMIKAVGWTILLTAYVWYPMLQQVLHQKINRPFRTKLQERALNISDSLIGAVN
                     NDLVTFTMGTIGVVSFILPLFFKKKFANKEKIINFCAVTTWFLSTNLFPWEFLQKTPI
                     QIIQFPWRILGFQVLFGSLILIIVFLKWKTSNKKSMCSLVGIVLLIFTVTVATEANYS
                     QKIQSYKGRLIMTKKDVTLYTTSRTGGLYDYAPLDALKYKDHLKKHEVKVYD"
BASE COUNT          655 a          263 c          307 g          662 t
ORIGIN      
        1 atggcctttt tacttttaca caattataag gactttatcg aaaaaaagca gttatttgtt
       61 aaaatcattg atattattaa taataagtat tttttgaaag gggaaatata aaaggttttt
      121 gaaaataaat aaaaaatagt attacttgtt ctattgctag ttattgctag tctttattct
      181 tttttgtttt ttagggatgt acaaaagatc tcaaccacag gagacattgc ttttcacttt
      241 tctagaataa aatgcttgtc ctcagtattt tctggtccaa taaattttac cacatttaat
      301 agctatggcg gaggcgtgaa tttttttatc catatctaac atctttccag ccgtaatatt
      361 ttactggaca acaaacaatt tgattctaag ttatatactt actatacgtt gggatactga
      421 atatctgtac aattctagtg agctatcaat atggacaaaa gaatagatgc agccttctta
      481 ttcagctgtt tgtatagctt ttatggattg atatatatta gcgtactgca atttcagaat
      541 caattgcgtt gacgattgta ccagttgtct tgtattacac atatactctt ctttatgaaa
      601 gaaaaaactg cgtgattctt ttagctgtca gtatgagttt gctcatctat acccatattc
      661 tctccacctt tatgagtgtg attgttattg gcttcttgtt tatcggctct cttttctcta
      721 agcggaaaga gagaaaagaa atgtcgaatc tgatatcaaa tatgataaaa gctgttggtt
      781 ggaccattct tttaacagct tacgtttggt atccgatgtt acaacaagtc ctacatcaaa
      841 aaattaatcg tccttttcgc acaaaacttc aagaaagggc attaaacatt tctgatagtt
      901 taatcggtgc agtaaataat gatttagtta catttacaat gggaacaatt ggtgtggttt
      961 catttattct tccacttttc tttaaaaaaa aatttgccaa taaagaaaag attattaatt
     1021 tttgtgcagt gaccacttgg ttcttatcaa cgaatctttt tccatgggaa tttttacaaa
     1081 aaacacctat tcaaatcatt cagtttcctt ggagaatctt gggttttcaa gtgctttttg
     1141 gttcattgat cttaattata gtgtttttaa agtggaaaac aagcaacaaa aaaagtatgt
     1201 gtagccttgt aggaatagtc cttcttattt ttacagtgac tgtagcaaca gaagcgaatt
     1261 attcgcagaa aattcaatcg tataaaggtc gtttaattat gaccaaaaaa gatgttacac
     1321 tttatacaac ctcgagaact ggaggtcttt atgactatgc accattagat gcattgaaat
     1381 ataaagatca tttaaagaaa catgaagtaa aagtctatga ttgatgggag aatgcatctc
     1441 ataaagcaca taattctaaa ataatctata cagtaggaga tgcgaatgag caaaatatca
     1501 cgttacctgt atttaattac tgggaacagt tatgaaagta aatgggaaaa agagcactat
     1561 agaaaatgac aatggtttag tgtctattaa aggtacggga aaaagaacta tagttgaggt
     1621 ttcatctacg tatccaacta cgatgattct atctttatta attagttcaa taacttttat
     1681 attcttattt acacgttatt taataagatg ctgcggttaa atgaaaatag attagataga
     1741 tattataaat atgttgattc tattttcata gcaatggaga aaatacatta gcaatatata
     1801 aaagaaggta tcaagagtca cggtgaattt attccgaaaa gtgaaaagaa caaatataaa
     1861 atttaataaa aatatagaac taaatag
//
LOCUS       DAFBVQ010000151         1863 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.157, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000151 DAFBVQ010000000
VERSION     DAFBVQ010000151.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1863)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1863)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1863
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.157"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..830)
                     /locus_tag="LLC22_002871"
     CDS             complement(<1..830)
                     /locus_tag="LLC22_002871"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK5436061.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFTGETVIT
                     YGFGHLVELDSPDMYDEKWKQWALEHLPIFPNQYHYHVPKDKKKQFSVVKRQLQSADT
                     IVIATDSDREGELIAWSIIQQAGANQGKTFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEVQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEAYLKEKGVQLGKQPGTILQVE
                     T"
     gene            complement(841..>1863)
                     /locus_tag="LLC22_002872"
     CDS             complement(841..>1863)
                     /locus_tag="LLC22_002872"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351562.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBK5436062.1"
                     /translation="ELKPKHERQNFLVGDDRLDHAVAFLWKDPQTGETVGASYQGTIV
                     DFNRFGKRGTYKHIDKNPTPNHGFNLKIGDPKHLKFFESSIDLLSYAALNREKLQDAW
                     LVSMDGLKHHVISHYVEESISELRRKQTFPQSIEICVDNDRAGHIFYEKEQMKGIVDP
                     FTNKKIRCERGIPNDWQVPKEYKATYEAVAKEMSVEPEAIMAIHKTETNLQLTNQLVS
                     AHDVQSTFGKMLAKGEPVETIDLKEACTTVAKELKVCERADGTYNFDRFYSRKANIKD
                     VNAGILLSYKAEQYYKGYKKHEHEFVPEVKKDWNDQLKHEIQQQEIRKQKRAMLFQQG
                     RQQERE"
BASE COUNT          459 a          402 c          327 g          675 t
ORIGIN      
        1 gtttcgactt gaaggatcgt acctggctgt tttcctaatt gaacaccttt ttcttttaaa
       61 taggcttcaa atgcttcttg tgtcgcttgg gtttcatttg gatcaagctt cgcatcaaat
      121 gcgccatttt gagcgattac ttgggctttt ccttcaaaat atggttcttt ttggaagttt
      181 ctaatctttt cctgcaattg ataaatcata tagagtgttg gggtttggac tctacctaaa
      241 gaaaaacttc ctggtatgcc tttttgctgc aagagtaaac tatacagtgg gctaccgttc
      301 atcccaatta accaatcggc gatctgacgt gcttgtactt cttcaaattt tggataggtc
      361 tcttctgcgt ctcgtaactg ttggaatccc tgataaatgg cttctttttc taaggagttg
      421 atccaaagtc ttttaaaggt ttttccttga ttggcgcctg cttgttgaat gattgaccag
      481 gcaatcagct ccccttcacg atcgctatca gtcgcgatca caatcgtatc agctgactgc
      541 agctgtcgtt tgacgacact aaactgcttt ttcttatctt taggaacatg atagtggtat
      601 tgattgggga aaataggcaa atgttctaat gcccattgtt tccatttttc atcgtacata
      661 tcgggcgaat ctaactcgac taaatgacca aaaccatacg tgatcacagt ttctcctgta
      721 aacaatcgat cttggatctc aaaataccca tcttttcggg tagctttaga aaagctatcg
      781 gcataagcct tcgcttgtga cggtttttct gctaaaatga cggttttcat agtgacgact
      841 tcactccctt tcttgttgtc tgccttgttg aaacaacatc gcacgttttt gctttctgat
      901 ttcttgttgc tggatctcat gcttcaattg atcattccaa tcctttttca cttcaggtac
      961 aaattcatgt tcatgctttt tatagccttt gtagtattgt tctgctttat aggaaagaag
     1021 gattcctgca ttaacgtctt ttatgttggc ttttctacta taaaaacgat caaagttgta
     1081 tgttccatct gcgcgttcac atactttcag ttccttcgcg accgtggtac atgcttcttt
     1141 caaatcaatt gtttctactg gttcgccctt cgccaacatc tttccaaacg tagattgaac
     1201 atcatgagca gacaccaatt gatttgtcag ctgtaaatta gtttcagttt tgtgtatggc
     1261 cataattgct tcaggttcaa cactcatttc ttttgcgact gcttcataag tagctttgta
     1321 ttctttaggt acttgccaat catttggaat tcctcgctca caacggattt tcttattggt
     1381 aaaaggatca acgattccct tcatctgttc tttttcataa aaaatatgtc ctgcacgatc
     1441 attgtccaca catatttcaa tcgattgagg aaatgtttgt tttcgtctta attcagaaat
     1501 cgactcttca acgtaatgac tgattacatg atgttttaac ccgtccatcg aaactaacca
     1561 ggcatcttgt agtttctccc gattcaatgc agcgtaactt aacagatcaa tactactttc
     1621 aaagaatttt aaatgcttcg gatcgcctat ttttaaatta aatccgtgat ttggcgtagg
     1681 attcttgtca atgtgtttat acgttccccg tttaccgaaa cgattaaaat cgacgatcgt
     1741 tccttgataa cttgccccta ctgtctctcc tgtctgtgga tctttccata aaaaagcaac
     1801 cgcatgatct aaacggtcgt ctccaactaa aaaattttgc cgttcatgtt tcggctttag
     1861 ttc
//
LOCUS       DAFBVQ010000152         1860 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.158, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000152 DAFBVQ010000000
VERSION     DAFBVQ010000152.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1860)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1860)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1860
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.158"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..1030)
                     /locus_tag="LLC22_002873"
     CDS             complement(<1..1030)
                     /locus_tag="LLC22_002873"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629570.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5436063.1"
                     /translation="MKSNEKTPLTTSLILLLSITCGVVVANMYYIQPIGTKVAASLSV
                     STSAVGILTMLTQLGYALGLLFLVPLGDVVDRPKLIIRMVALSAVSLLAAFFAPSFTL
                     FACASFLIGLLSIVPQIIIPYGAVLAGPKARGKVMGTLLSGLLVGILLSRTVSGIVAS
                     LFSWRMIYLFALCAVGILTLLLYWKMPRSVQQSSTAVSYLDSLKSLPHLVASQRLLRE
                     AAVSGFFMFGTFSIFWSTLIFYISSPAYNWGTFEAGILAIFGLSGAVAAPIVGRLADS
                     YSERKIVYMGLVMQTISFIALLVGGSHLAILLLAIILLDVGNQFGQVANQTRVQGLGE
                     AASNRNNTV"
     gene            complement(1112..1801)
                     /locus_tag="LLC22_002874"
     CDS             complement(1112..1801)
                     /locus_tag="LLC22_002874"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002294589.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TVP38/TMEM64 family protein"
                     /protein_id="HBK5436064.1"
                     /translation="MKKKIIRLMLISLGIILILVVGYRLYLEYQTDIQLFLNPRASKA
                     ELLAHIRSHGTFASILLIVLTAVMCAVPGIPTSVVGVIAGLSFGPLTGAIINILGNAL
                     GNITAIFLMHRLKFLDKKTETNHWVQAIRQMKHPKIGVMLGYMIPVIPSSMVNFAADA
                     MKLPLQQIILSIVIGVIPSSVLYACGGEALFHGYNKTAVTLVASVTVLVGLVVFIYKD
                     RKKKQGKQKHK"
BASE COUNT          629 a          416 c          322 g          493 t
ORIGIN      
        1 atacagtatt atttcggttg cttgctgctt cacctagccc ttgtactcgt gtttgattgg
       61 cgacttgacc aaattgattc ccgacgtcta ataaaataat agctaaaagc aaaatggcca
      121 aatggcttcc gccaaccaat aaagcaataa agcttattgt ttgcataaca agtcccatat
      181 acacgatttt tctttcagaa taagaatctg ccagtcgtcc cacgataggt gcagcaactg
      241 ctccagacaa accaaaaatc gctaatatcc ctgcttcgaa tgttccccaa ttgtaggcgg
      301 gactgctgat ataaaaaatc aacgtagacc aaaagatcga aaatgttcca aacatgaaaa
      361 atccactgac tgccgcttct cttaatagac gttgagaagc aactaaatgc ggcaaacttt
      421 taagtgaatc aaggtatgaa acagctgtac tactttgctg gacagaacgc ggcattttcc
      481 agtaaagcag aagtgtaaga attccgactg cacataaagc aaataaatag atcatccgcc
      541 aagaaaaaag actggcaaca ataccagata ccgtccgaga aagcaaaatc cccacgagta
      601 aaccgctaag caatgtaccc atgaccttcc ctcttgcttt tggtcccgct agtaccgcac
      661 cgtaaggaat gatgatttgc ggcacgatcg aaagtaatcc tattaaaaaa gaagcgcatg
      721 caaataacgt aaacgaaggc gcaaaaaaag cggccaacag agagacggca gataacgcta
      781 ccattcgaat gatcaatttt ggacgatcca ccacgtcccc taaaggaact aaaaacagta
      841 accctaacgc atagcctaat tgggtcaaca tcgtcaatat cccgactgca cttgtgctaa
      901 cagataaact agctgctact tttgttccaa tcggctggat gtaatacata ttggcaacaa
      961 caacgccaca agtgattgat aatagtaaaa taagcgaagt tgttaaaggt gttttttcat
     1021 tactcttcat tgatttcccc catttcctat cttagtttac aacttatgga aaagattgga
     1081 aatagaaaaa tacaactatt cgccacactt attatttgtg cttttgtttt ccttgttttt
     1141 tcttgcgatc tttataaatg aagacaacta accctactag cacagtaaca cttgcaacca
     1201 acgtgactgc agttttgtta tatccgtgaa acagagcttc tccaccacac gcatacaaca
     1261 cagacgaagg gatgactcca atcacgatcg acaatatgat ttgctgtaga ggcaatttca
     1321 tcgcatctgc agcaaaattg accatagaag atggaataac cggtatcata tagcctaaca
     1381 ttacacctat ttttggatgt ttcatttgtc ggattgcttg cacccaatga ttcgtttcgg
     1441 ttttcttatc taaaaatttt aagcgatgca taaggaaaat tgcagtgatg ttaccaagag
     1501 cattacccaa aatgttgatg atcgcacctg tcagtggtcc aaagctcaaa ccagcaatga
     1561 ctccaactac tgaagtagga atacctggaa cagcacacat caccgctgtc aatacgatca
     1621 agagtatcga tgcaaaagtc ccatgcgaac gaatatgtgc gagtagctct gccttactcg
     1681 ctctcggatt taaaaataat tggatgtctg tctgatattc taaatacaac cgatagccca
     1741 ctaccagtat cagaatgatt cccaacgaga tcaacatcaa tcggattatt ttctttttca
     1801 tatttcctcc tgaaaaaaat ctatattcat taaataatag tttaacataa aaacaaaaaa
//
LOCUS       DAFBVQ010000153         1854 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.159, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000153 DAFBVQ010000000
VERSION     DAFBVQ010000153.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1854)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1854)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1854
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.159"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..830)
                     /locus_tag="LLC22_002875"
     CDS             complement(<1..830)
                     /locus_tag="LLC22_002875"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002369673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA topoisomerase III"
                     /protein_id="HBK5436065.1"
                     /translation="MKTVILAEKPSQAKAYADSFSKATRKDGYFEIQDRLFSGETVIT
                     YGFGHLVELDSPDMYDENWKQWSLEHLPIFPTHYHYHVPKDKKKQFKVVKQQLQSADT
                     IIIATDSDREGELIAWTIIQQAGADHGKIFKRLWINSLEKEAIYQGFQQLRDAEETYP
                     KFEEAQARQIADWLIGMNGSPLYSLLLQQKGIPGSFSLGRVQTPTLYMIYQLQEKIRN
                     FQKEPYFEGKAQVIAQNGAFDAKLDPNETQATQEAFEDYLKEKGVQLGKQPGTIHQVE
                     T"
     gene            complement(841..>1854)
                     /locus_tag="LLC22_002876"
     CDS             complement(841..>1854)
                     /locus_tag="LLC22_002876"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014401506.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="toprim domain-containing protein"
                     /protein_id="HBK5436066.1"
                     /translation="ELKPKHERQNFLVRDDRLDHAVAFLWKDPQTNETVGASYQGTFI
                     DYERFGERGTYKHIDKNSTANHGFNLKIGDPKQLKFFESSIDLLSYAALNRDQLNDTW
                     LVSMEGLKHHVISHYFGEAVSELRKKQAFPQSIEICVDNDRAGHIFYEKEQLMGAVDP
                     FTNQKVRCERGIANDWQVPKEYKVIYEEVAKEEKITPEAIMAIHKTENNLQLTNQLVS
                     AHKVNASFGQQLSVNDSIEAINLKDICREVAKELKACERVDGTYDFDRFYQEKGDINA
                     QILFSYKAEQYYKGYKNHEHEFVPEVKKDWNDQLKHEIYQQEIRKQKRAMLFQQGRQQ
                     ERE"
BASE COUNT          471 a          399 c          322 g          662 t
ORIGIN      
        1 gtttcaactt ggtggatcgt acctggctgt tttcccaatt gaaccccctt ttcttttaaa
       61 taatcttcaa atgcttcttg cgtcgcttgg gtttcattcg gatcaagctt cgcatcaaat
      121 gcgccatttt gagcgattac ttgggctttt ccttcaaaat atggttcttt ttggaagttt
      181 ctaatctttt cctgtaattg ataaatcatg taaagcgttg gggtttggac tctgcctaag
      241 gaaaaacttc ctggtatgcc tttttgctgc aagagtaaac tatacagcgg gctaccgttc
      301 atgccgatca accaatcggc gatctggcgt gcttgtgctt cttcaaattt tgggtaggtc
      361 tcttctgcat ctcgtaactg ctggaatccc tgataaatgg cttctttttc taaggagttg
      421 atccaaagtc ttttaaatat ctttccatga tcggcgcctg cttgttgaat gatcgtccaa
      481 gctatcagtt ccccttcacg atcgctatct gtcgcaataa taatggtgtc ggccgattga
      541 agttgctgtt tcaccacctt gaattgcttt ttcttatctt taggaacatg atagtgataa
      601 tgtgtaggga aaataggcaa atgctctaat gaccattgtt tccaattttc atcgtacata
      661 tcgggcgaat ctaactcgac taaatgacca aaaccatacg tgatcacagt ttctcctgaa
      721 aacaatcgat cttggatctc aaaataccca tcttttcggg tagctttaga aaagctatcg
      781 gcataagcct tcgcttgtga cggtttttct gctaaaataa cggttttcat catgacgatt
      841 tcactccctt tcttgctgtc taccttgttg aaacaacatg gcacgttttt gctttctgat
      901 ctcttgttgg tagatttcat gcttcaattg atcattccaa tcctttttta cttcaggtac
      961 aaattcatgt tcatgatttt tatagccttt gtagtattgt tctgctttat aagagaaaag
     1021 aatctgagca ttaatatccc ctttttcttg ataaaaacga tcaaaatcgt acgtaccatc
     1081 cacgcgttca caagctttta attcttttgc gacttctcta caaatatctt tcaaattaat
     1141 agcttctatt gaatcgttaa cagaaagctg ctgaccaaaa gacgcattta ctttgtgagc
     1201 ggaaaccaat tggttcgtta attgcagatt gttttctgtc ttgtgtatgg ccataatagc
     1261 ttctggtgtg atcttttctt cttttgcgac ttcttcataa atgactttgt attcttttgg
     1321 cacttgccaa tcattagcga ttcctcgttc acaacgtact ttctgattcg taaatggatc
     1381 aactgcgccc attaattgtt ctttttcgta gaaaatatgt cctgcacggt cattatccac
     1441 acaaatctcg atggattgag gaaaggcttg tttctttctc aattcagata ctgcctcacc
     1501 aaaataatga ctgatcacat ggtgttttaa cccttccatc gaaactaacc acgtatcgtt
     1561 taactgatca cgatttagtg cagcatagct aagtaaatca atactactct caaaaaattt
     1621 taactgctta gggtcaccga tctttaggtt aaagccatga ttcgctgtcg aatttttatc
     1681 tatatgctta tatgtgcctc tctcaccaaa acgttcataa tcaatgaacg ttccttgata
     1741 actcgcccct actgtctcat ttgtctgtgg atctttccat aaaaaggcga ccgcatgatc
     1801 taaacgatcg tctcgaacta agaaattttg ccgttcatgt tttggcttta gttc
//
LOCUS       DAFBVQ010000154         1718 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.160, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000154 DAFBVQ010000000
VERSION     DAFBVQ010000154.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1718)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1718)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1718
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.160"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(606..962)
                     /locus_tag="LLC22_002877"
     CDS             complement(606..962)
                     /locus_tag="LLC22_002877"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344588.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="arsenate reductase"
                     /protein_id="HBK5436067.1"
                     /translation="MEVKVYGSAHCVTSLKAKQWLEHHQLPYQFVDLEERDLSTEEAE
                     ELCSFEEVQAEQLFATWSEAFHNIAIDLSCVGKKQLIFLCTQHTNLLRRPLIIIDEVL
                     FIGYNEQLMEQLILNK"
     gene            complement(976..1386)
                     /gene="spx"
                     /locus_tag="LLC22_002878"
     CDS             complement(976..1386)
                     /gene="spx"
                     /locus_tag="LLC22_002878"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transcriptional regulator Spx"
                     /protein_id="HBK5436068.1"
                     /translation="MIKVYTSPSCTSCRKARAWLQANQLEFEEKNIFAEPLTESEIKK
                     ILAATEGGVQDIISTRSKIYEKLGIDFNELTLKQMIVLFKEYPSLLRRPILIDEKRIL
                     IGFNEDEIRSFVPREIRCVARNLIYLQNNNILNS"
BASE COUNT          529 a          315 c          242 g          632 t
ORIGIN      
        1 tgtttgttgt cttgaattga atcaagacgc cctacacatt tggtttgtct tactttgttc
       61 agttttcaaa ggtctacttc atcaggagtg ttccccgatt cgtttttggc tgccgtagca
      121 acttttatat catatcagag agacaagtaa ttgtcaactc ttttttaaaa gtttttttga
      181 tttcgttttt cgaaatctta cagcaactca tttatcataa cttatcattt gttatttgtc
      241 aaggactttt ttgaagtttt tttcgataga atcaagcttc acaagtggtt cttttttaac
      301 aactcagtta tcttatcatg tcatttctaa catgtcaaca actattttat atgtttttta
      361 aaatactatt ttattgcttt gctacttaaa acaacagaaa tgaatatatc atgtaaattt
      421 acacatgtca atatattttt aactctatat ccccacctag atttgaattt tgaccacata
      481 aattgagcat gtctctatag tagaaaaata aagtcaaaaa aagaacacat aacacgcttg
      541 atgctaagtg ttcgactgtt acaactgtat gaaatgctca gtgacttgat taaaacagtt
      601 aaagtctatt tatttaagat aagctgttcc atcaactgct cattgtatcc aataaataga
      661 acttcatcga taataatcaa aggacgtctg aggagattgg tatgttgtgt gcataaaaaa
      721 atcagttgtt tttttcctac acaggaaagg tcaatcgcaa tgttgtgaaa agcctcagac
      781 caagtcgcaa atagctgttc tgcttgcact tcttcaaaac tgcataattc ttctgcttct
      841 tctgtactta gatcgcgttc ttctaagtca acaaattgat aaggcaattg atggtgttct
      901 aaccattgtt tcgccttcag acttgttaca cagtgcgctg atccatagac tttcacttcc
      961 acgaaggctc cctccctatg aatttaagat gttattgttt tgtaaataga tcagatttct
     1021 ggcaacacat cgaatttcac gagggacaaa tgaccggatc tcatcttcat taaatccgat
     1081 tagtattctt ttttcatcaa tcaaaatagg tcgtctcaat aatgaaggat attctttgaa
     1141 taagacgatc atttgcttta aagttaattc gttaaaatct atgcccagct tttcgtaaat
     1201 tttcgaccga gtggaaataa tatcttgaac tcctccttca gtcgctgcca agatcttttt
     1261 gatctcactt tctgttaacg gttcggcaaa aatattcttc tcttcaaatt caagttgatt
     1321 cgcttgcaac catgctcttg cttttctaca ggaagtacag ctaggcgaag tatatacttt
     1381 tatcattttc tcactccttt ttaattataa tccaattcta cagtaatttc ttttaaaata
     1441 ccaattatta gctaataaaa tataaaaaaa atcaaaataa ctgattattt acgtttgaat
     1501 aatgagaatt tttctatata ttctctattt tgataatagt attctcattt tcaaaataaa
     1561 taagggaggt gtgacaaaat tcttgtcaca cctccctttt ccgaataaac tgtgttccag
     1621 aaatagcttc ttcgaaaata agctgaaatt tcacaaaaat ttgagaagca attttcgtac
     1681 attccttctt ctttcttgaa actgaccact tctgtcac
//
LOCUS       DAFBVQ010000155         1685 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.161, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000155 DAFBVQ010000000
VERSION     DAFBVQ010000155.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.161"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(45..779)
                     /locus_tag="LLC22_002879"
     CDS             complement(45..779)
                     /locus_tag="LLC22_002879"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_019723412.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aquaporin family protein"
                     /protein_id="HBK5436069.1"
                     /translation="MDYSLMTRLAAEMIGTALLIVLGNGAVANVDLKGTKGYGSDWML
                     IAVGYGFGVMMPAMIFGGISGNHINPAFTIALASNGLFPWAEVVPYIIAQLIGAAIGQ
                     LIVVACYKPYYDQTEDVNHVLGTFSTINSVGSKFNGFVNEFFGSFVLFFGALGITKAP
                     FFQDNLGTAHLALGFLVWTLVASLGGPTGPGLNPARDFAPRLVHALLPLKHKGSSQWG
                     YAWVPVVAPICAGVVAVFLYKLLFMA"
     gene            1106..1516
                     /locus_tag="LLC22_002880"
     CDS             1106..1516
                     /locus_tag="LLC22_002880"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002309804.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="CidA/LrgA family protein"
                     /protein_id="HBK5436070.1"
                     /translation="MKFFQEFFIIIFFSVLGEGIRIFAHLPIPGSILGILFLFLAFEM
                     HLVDPEKIGATGDFLLNNLAILFVPAGVGLLEYFDDIASIWPVLLGAVVVCSIVTMVA
                     AGKTAEGVEALLGYVRKKKAERVSVNEMEENQID"
     gene            1509..>1685
                     /locus_tag="LLC22_002881"
     CDS             1509..>1685
                     /locus_tag="LLC22_002881"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005880671.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LrgB family protein"
                     /protein_id="HBK5436071.1"
                     /translation="MTEFFVNPLFGLSLTLGVYVLSDKFLRKYKLPVLNPLVLSIVVI
                     ILFLHFSGISYKDYN"
BASE COUNT          536 a          294 c          325 g          530 t
ORIGIN      
        1 ttggtacgca atcgctgtac caagtttttt tatttagctt ttgattaagc cataaataat
       61 aatttatata agaatactgc tacgacacca gcacagatag gtgctacaac tggtacccat
      121 gcatatcccc attgagaaga acctttatgt ttcaatggaa gaagtgcgtg tacaagacgt
      181 ggagcaaagt cgcgggctgg gtttagtcca ggacctgtag gaccaccaag tgaagcaact
      241 aatgtccata caaggaaacc aagtgctaag tgagctgtac caagattatc ttggaagaat
      301 ggtgcttttg taatacctag ggcaccaaag aataaaacga atgaaccaaa gaattcattg
      361 acgaaaccat tgaatttaga accaacgctg ttgattgttg agaatgtacc taacacatgg
      421 tttacgtctt ctgtttggtc gtagtaaggt ttgtaacaag ctactacgat caattgtcca
      481 atcgctgcac caatcaattg tgcaatgata taaggaacaa cttcagccca agggaataga
      541 ccattagatg ctaaagcaat tgtaaatgct gggttgatgt ggttaccgct gattccacca
      601 aaaatcattg ctggcatcat aaccccgaat ccatacccga cagcaatcag catccagtca
      661 ctgccatatc cttttgtacc ttttaaatct acgtttgcta cagcaccgtt acctagaacg
      721 attagtaatg ctgtaccaat catttccgcc gcaagacggg tcattagtga gtaatccata
      781 aatacctcca aaagttataa aaatgcaaaa aaaaaagaaa catcaacacg aaaagcatcg
      841 gtgcagtgtt tcgtgtcgga aggatttctg cagtcttaac aaatgtgaat aaaaaaatga
      901 attccattac ttataagaaa ccagaccaac agtaaaactc caactctttt taaaagttct
      961 ccacaaatca ccaagcttaa ctataaatat accaaaaaaa aaacgttttt tttctcaaaa
     1021 attgtatctt agaaacagca tgttttgaaa ctttcagaaa aggtttgtta gtaaaatgaa
     1081 agctatacgt aaggagtgtt gtttgatgaa attttttcaa gagtttttca ttattatttt
     1141 cttttctgta ttaggagaag gcatacggat ttttgctcat ttacctattc ctggaagtat
     1201 cttaggtatt ctttttttat ttttagcatt tgaaatgcat cttgttgatc ctgaaaaaat
     1261 cggagcaact ggtgattttt tattgaataa tctagccatt ttatttgttc ctgctggtgt
     1321 aggtttattg gaatattttg atgatattgc ttcgatatgg cctgttttac tgggagcagt
     1381 cgtcgtgtgt tccatcgtca cgatggttgc agcgggaaaa acggcagaag gtgtagaagc
     1441 tttgctgggc tatgtccgta agaaaaaagc agaaagggta tctgtaaacg aaatggagga
     1501 gaatcaaatt gactgagttt tttgtgaatc cattatttgg cttaagtttg actttaggag
     1561 tgtacgtatt atctgacaaa tttttgcgga aatataaact gcctgttttg aatcctctcg
     1621 tattatcgat tgttgttatt atcttatttt tgcatttttc tgggatcagc tataaagact
     1681 ataat
//
LOCUS       DAFBVQ010000156         1622 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.163, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000156 DAFBVQ010000000
VERSION     DAFBVQ010000156.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1622)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1622)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1622
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.163"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            216..722
                     /locus_tag="LLC22_002882"
     CDS             216..722
                     /locus_tag="LLC22_002882"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436072.1"
                     /translation="MDIKWLVQQNDSNLELAIKYLEETIFEDEHLTDNFLQVLKYLEI
                     YSVKKNKLIGENDSPIKTPIELSLRNRMGILQRSEIVKELFYHKFSYEIRLDDTYEHY
                     RIVFFVYNSIEDATATTALTFGFTKNGTINSDKTRQAATESDDICKKVCNGEENYWIG
                     EEKLNEIY"
     gene            709..1161
                     /locus_tag="LLC22_002883"
     CDS             709..1161
                     /locus_tag="LLC22_002883"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305550.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436073.1"
                     /translation="MKSINDLLKKHPDLYKKLNSEQRNLSKQLLKIRLKKQKNVTEFS
                     KMLGISEKKYLEFEFGDMHIPVAEYNKLLKQVENLSYKDSMNFTIKVAGGPIKYDRIE
                     NKPYIRNKSYSVFKSRKRKEVSSNMVYASVNYQDTSRYIVEKEVYVHG"
     gene            1154..1552
                     /locus_tag="LLC22_002884"
     CDS             1154..1552
                     /locus_tag="LLC22_002884"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347086.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436074.1"
                     /translation="MDKGNSVTFALENISLNKIHFELTDNFSYGDLEFNIELGYKEDE
                     AEYLEKKLVSLRAHIVGGMEGAPVDILLFSVIRVSTNEQPYKKLVEESMGELAKPILN
                     KASNLISNLYSEVGVMPTVIDLYQLYSQQK"
BASE COUNT          644 a          190 c          270 g          518 t
ORIGIN      
        1 cgtaaactag tttggtaata caattgtaat ttattttcag tatttaaaca tttctacctt
       61 attacattat gttaactaaa ttgcttataa aataagctaa tttttattga caagcaggat
      121 gtactatagt taaacttaaa ataagataca aatatatata atatgcttat acatatagta
      181 atatttacta atattgaaac aggtggttta gtgagatgga cattaagtgg ttggttcaac
      241 aaaatgatag caatttagaa ttggcgatta aatatctcga agaaactatc tttgaagatg
      301 aacatcttac agataatttt ttacaagtat taaaatatct tgaaatttac tctgttaaaa
      361 aaaataaatt aattggtgaa aatgattctc caataaaaac acctattgag ctaagcttaa
      421 gaaatcggat gggaatactc caaagatcgg aaatagtaaa agaacttttt tatcataaat
      481 ttagttatga aataagacta gatgatactt atgagcatta tagaattgtt tttttcgtat
      541 acaattctat agaagatgct actgcgacta ctgcattaac attcggtttt acgaaaaatg
      601 gaacaatcaa ttcggataaa acccgtcaag ctgctacaga aagtgatgat atatgtaaga
      661 aagtatgcaa tggggaagag aattactgga taggggagga aaagttgaat gaaatctatt
      721 aatgatttat taaaaaaaca tcctgattta tataaaaaat taaattctga acaaagaaac
      781 ctgtccaaac aattacttaa aataagatta aaaaaacaaa aaaacgtgac agaattctca
      841 aaaatgttag gaataagtga aaaaaaatat cttgaatttg agttcggaga tatgcatatt
      901 cctgttgcag agtacaataa acttttgaaa caagttgaaa atttgtccta taaagattca
      961 atgaatttca ctattaaggt tgctggcggc cctattaaat atgaccgtat tgaaaataaa
     1021 ccttatattc ggaataaaag ttactcagta tttaaaagta gaaagagaaa agaagtatcg
     1081 tcaaatatgg tctatgctag tgttaattac caagatacga gccgctatat tgtagaaaaa
     1141 gaggtatatg tacatggata aaggaaatag tgttactttt gcacttgaaa atattagttt
     1201 gaataaaatt cattttgaat taactgataa ttttagttat ggagatttag agtttaatat
     1261 tgaacttgga tataaagaag acgaagcaga gtatctagaa aaaaaacttg tttctttacg
     1321 agctcacatt gtagggggga tggaaggagc accggtagat attttactct tttcagttat
     1381 tcgtgtttct acaaatgaac agccatataa aaaattagta gaagaatcta tgggagagct
     1441 agctaaacct atcctgaata aagcttctaa tttgatttct aatttatata gcgaagtagg
     1501 agttatgcct acagttattg atttatatca gctatatagt caacaaaaat aaaatacaag
     1561 taatagagtt atctatttaa atttgcaaga caaagacctc aaccagtcat ccttggttga
     1621 gg
//
LOCUS       DAFBVQ010000157         1584 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.164, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000157 DAFBVQ010000000
VERSION     DAFBVQ010000157.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1584)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1584)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1584
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.164"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            292..1479
                     /locus_tag="LLC22_002885"
     CDS             292..1479
                     /locus_tag="LLC22_002885"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297293.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBK5436075.1"
                     /translation="MYFLGIDIGKRTHVASIMNEEGKVLLKGFSFPNTTEGAESLIER
                     MVDYSGAPSDFVIGMEATGHYWLSIFSYLHESDYLIHVVNPLQTDGWRKGTEIRKRKN
                     DIIDSVLIADLMRYGSFVETVLSDENVFSLKQLSRYRTYLVGTASDFKRKIIAVLDQV
                     FPEYATIFTKQGVFGKASKELLLAFSAPIDLENISSETLAQYLAELSRNRIKAEKADQ
                     LKQAASNSFGVKFAQEAFTFQLRSMIEQLKFIESQIKETEREIKHIMDTLNSVILTIP
                     GIGPINGATILGEIGDIQKFSNPKKLVAYAGIDASVTQSGQYEATHNVMSKRGSPYLR
                     KALFSAALVASQCDPVFSAFYQKKVSEGKHHLTALGAVSRKLCYVIHAILTKNEPYII
                     VSD"
BASE COUNT          467 a          296 c          316 g          505 t
ORIGIN      
        1 ttttaacctt ccggttttga ttggataacc ctatgaacca tcgttatttt aatttggtat
       61 taactcattt cttttgagat aatatattta ttggattgag aggctaagcc gttcccccct
      121 tgggccattg aacccgcact cgagagactg gctcctctct ctgataagtg gattgcgtat
      181 gagttagatg ttgaaagtcc ttactttact ccgtatctcg tacaaggtag tgacgctttt
      241 cagttgagtg gatttcaatc caaaattctt tttttgaaag gtcagatata catgtacttt
      301 ttaggcattg atatcggtaa acgcactcac gttgcttcta tcatgaacga ggaaggaaag
      361 gtattactaa aaggtttttc atttcctaac accactgaag gagcagagtc attaattgag
      421 cgaatggtcg actattccgg agcacccagt gactttgtta tagggatgga agccacgggg
      481 cactattggc tgtccatctt ttcatacctt cacgaatcag attatttgat tcacgttgtg
      541 aatccccttc aaacagacgg atggcgtaaa ggtacagaaa tacggaaacg aaaaaacgat
      601 attattgatt ctgttttgat tgctgactta atgcgctatg gctcatttgt cgaaacggtc
      661 ttatccgatg aaaatgtttt ttctttgaaa caactttctc gttaccgaac ttatttagta
      721 ggtacagcga gcgacttcaa aagaaaaatt atagccgtat tggatcaagt ctttccagaa
      781 tacgcgacga tttttaccaa gcagggcgtt ttcggaaaag cttctaaaga gttattgctg
      841 gcgtttagtg ccccgatcga cttagaaaac atttcctcag aaactttggc ccaatactta
      901 gctgagttaa gcaggaaccg aatcaaggca gaaaaagcgg accaattgaa gcaagcagct
      961 tctaactcct ttggagtaaa atttgctcaa gaagcgttca ccttccaact acgttcaatg
     1021 attgaacaat taaaattcat tgaaagccaa ataaaggaaa cggaaagaga aatcaagcac
     1081 ataatggaca ctttaaattc tgttattctc acaattcctg gaattggtcc tataaacggt
     1141 gcgactattc ttggtgagat cggagatatt caaaaatttt ctaacccgaa aaaactcgtt
     1201 gcttacgctg ggatagacgc ttccgtgaca caatcagggc aatatgaggc aacgcataat
     1261 gttatgagta aacgagggtc tccatatttg cgaaaagcct tgttttcggc ggctttagta
     1321 gcttctcaat gtgatcctgt ttttagtgcg ttttaccaga aaaaagtttc cgaaggaaaa
     1381 catcatctaa ctgccttagg tgcggtttct cgtaagcttt gttacgtgat tcatgctatt
     1441 ttgactaaaa acgagcctta tataattgtt tctgattagc tattgaacat tcaaaaaaac
     1501 taatggtaag aagcttattt gttgtaccct tttttcggaa ttatctgtta taaaatattt
     1561 tttgatttgg ctaattttta cttg
//
LOCUS       DAFBVQ010000158         1582 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.165, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000158 DAFBVQ010000000
VERSION     DAFBVQ010000158.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1582)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1582)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1582
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.165"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            129..1298
                     /locus_tag="LLC22_002886"
     CDS             129..1298
                     /locus_tag="LLC22_002886"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328814.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256 family transposase"
                     /protein_id="HBK5436076.1"
                     /translation="MTKFTIEIMQTLLNKGDLDELFQDHLERAINSLLQAELTAFLDY
                     EKYDRNGFNSGNSRNGNYSRTFKTEYGELNLTIPRDRNGEFSQQTLPAYKRTNDSLET
                     TIIQLFQKGITMAEISKLIEKMYGHHYTPQTISNMSKLVAEDVLAFKERTLEANYSVI
                     FMDATHIPVKRQTVSKEAVYITIGIRLDGTKEVLGFTIAPTESAYIWKEVLQDLRKRG
                     LEEVLLVVTDGLSCIEESIHSVYPNAQFQQCCVHVSRNIAHKVRVRGRKEICEDFKLV
                     YQANSKEEALDHIDFMTRKWKKQYPRVVNLLLNPALLTFYNFPHAIRRTIYSTNLIEG
                     FNKQLKRYTRRKEQFPNEESLERFFISQFNQYNQKFLGRIHKGFKEIQDTLESMI"
BASE COUNT          569 a          254 c          258 g          501 t
ORIGIN      
        1 aatatcccat attttaaaat aaaagatagc gtaaaatatt ttgtgtaaat agaaatttag
       61 ggtagaaaaa aaagtccatt ctgtaaaatt aaagttacca cacagaaatt ttataggagg
      121 actttctcat gactaaattt actatagaaa ttatgcaaac actactcaat aaaggggatt
      181 tagatgaatt atttcaggat catttagagc gagcgattaa ttcacttcta caagcagagc
      241 taactgcttt tttagattac gaaaaatatg atcgaaatgg attcaattca ggaaattccc
      301 gtaacgggaa ttattcacgt acatttaaaa cagaatatgg cgagttgaat ttaactattc
      361 ctagagatcg gaatggcgaa ttttctcaac aaacactacc agcatataag cgaaccaatg
      421 attcattaga aacgaccatt atccaattat ttcaaaaagg cattactatg gctgaaatct
      481 ccaaattaat tgaaaaaatg tatggtcacc actatacgcc acaaacaatc tccaacatga
      541 gtaaattggt ggctgaagat gttttagctt ttaaagaaag aacgttagaa gccaattatt
      601 ccgttatatt tatggatgcg acgcatatcc ctgtgaagcg acagactgtt tcgaaggaag
      661 cagtgtatat tacgattggt attcgtttgg atggaaccaa agaagttctt gggtttacta
      721 ttgccccaac tgagtctgct tatatttgga aagaagttct tcaagatctt agaaaacgtg
      781 ggttagaaga agttttatta gtagtgacag acggattaag ctgtattgaa gaaagtatcc
      841 atagtgtgta tccgaatgcc caatttcaac aatgttgtgt gcatgtatct agaaatatcg
      901 ctcataaagt tcgtgttcga ggtcgaaaag aaatttgtga ggatttcaaa ttggtttacc
      961 aagcgaattc aaaagaagag gcattggatc acatcgactt tatgactagg aaatggaaaa
     1021 agcagtatcc aagagtcgtc aatttactct tgaatcctgc cctattaacc ttttataatt
     1081 tccctcacgc catcagacga acaatttatt cgacgaacct gattgaaggc tttaataagc
     1141 agctaaaacg atatactcga agaaaagaac aattccctaa tgaagaatct ctagagagat
     1201 tcttcatttc tcaatttaat caatataacc aaaaattttt aggtagaatt cacaagggat
     1261 ttaaagaaat tcaggataca ttagagtcga tgatttaact gtaattaaca gaatggattt
     1321 tccatttaca tataattctt gacgctacca taatctaaat aaccatcata ttcatctact
     1381 acttatataa ttgagtttta ttaaactttt taagtttcta ttctatcaaa tatttaaaca
     1441 atctctgcat ccgaaaagac tacctcgtat agttttacta acaatatttt tattagcgtg
     1501 ttcaaatcct gatttcttgt atcaattatt ttctgttcac tttcaataag aaaaaagtct
     1561 ttacttccat ggataataat aa
//
LOCUS       DAFBVQ010000159         1504 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.166, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000159 DAFBVQ010000000
VERSION     DAFBVQ010000159.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1504)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1504)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1504
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.166"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(312..611)
                     /locus_tag="LLC22_002887"
     CDS             complement(312..611)
                     /locus_tag="LLC22_002887"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436077.1"
                     /translation="MLFNETQLWFKFDPSNRFVKDFYKVWDSEVFFLAIEDSLLINLY
                     YSNKNYFKIPAAKTRMKKDVYFLFDIVTDVLDARSDHRRYDYIKYTFVDPERYKD"
     gene            complement(617..847)
                     /locus_tag="LLC22_002888"
     CDS             complement(617..847)
                     /locus_tag="LLC22_002888"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002378238.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436078.1"
                     /translation="MMEEFIRKNISDEYADFYEQSNEKDKFQMDVSILAILAFSENKQ
                     PVTAKKETVFSEGKIKTRYILEVETKFKNRSE"
     gene            complement(1097..1297)
                     /locus_tag="LLC22_002889"
     CDS             complement(1097..1297)
                     /locus_tag="LLC22_002889"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002286470.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
                     /protein_id="HBK5436079.1"
                     /translation="MKINYTVDLVSFSLVINFSLFSLRLFIDGLRHTHASILLYQGVN
                     ILSVSKRLGHSSLETTMSTYTK"
BASE COUNT          535 a          243 c          219 g          507 t
ORIGIN      
        1 attgtgagat aataataaag aagagtttaa agcgttcccc aaaaaccact gccccataag
       61 tgtgttacgc tttaaactct tttatatttg aagccattaa aaagcatacc atatttttga
      121 aaaaaagtga gaaaaaaggc ttataattgg agtggtagtt aattagtgac ttatttttga
      181 ttttatagca ctgatactat aaaatataga tatcatcata ttacacaatc ttaatactaa
      241 cttaaaaaat atctcctttc ataagtatgg tgataaaatc cgttccgggc taccttttta
      301 ggtagcctac tttaatcttt gtatctttct ggatcaacga aagtatactt tatatagtca
      361 taacgccgat gatcgcttcg agcgtctagc acatcagtca cgatatcaaa caaaaaatat
      421 acgtctttct tcattctagt tttcgcagca gggattttaa agtagttctt attagaatag
      481 tagagattaa ttaataagct atcttcgatt gctaaaaaga aaacttctga atcccacacc
      541 ttataaaaat ctttgacaaa tctattcgaa ggatcaaatt taaaccataa ttgcgtctca
      601 ttaaaaagca taaccattac tccgatctat ttttaaactt agtctctacc tctaatatat
      661 atcgagtttt tattttgcct tcagagaata ctgtttcttt ttttgcagtt acaggttgtt
      721 tattttcgga aaaagctaat atagctaaaa ttgaaacatc catctggaat ttgtcttttt
      781 cgttgctttg ctcataaaaa tctgcatatt catcactaat attttttcta ataaattctt
      841 ccatcataaa gatcacctcg aaaagagtat acgaacaaac gttctttttg taaaggtgga
      901 atttattata ctaaataaat aggtgaacaa gtacttgtgc caaattatgt gccaaaaaaa
      961 atcgaattta ataaaacaca aacaaaaaga aatcctatta tgataacatt tcttataata
     1021 acaaacacaa cagaagacgt gtaatagtta gtcaggaacg tacaaataac ccctgtatcc
     1081 tttgcggtac agggggttat tttgtataag tagacattgt agtttctaaa ctgctatgtc
     1141 ctaaacgttt cgatacgcta agtatattta ctccttgata aagtaaaata gatgcatgcg
     1201 tatgtcttag tccatcaata aacagtcgaa gagaaaatag ggaaaaattg attactaaag
     1261 aaaaacttac taggtcgacg gtgtagttga ttttcatact tcaatagatt cgaattaaac
     1321 gatttcgatt ggcttatacc agtcctatcc aacgaaagat atatcgttct taactctagc
     1381 ggtataactt gaagctttac gtaaagccaa tgggaatgaa ctggagatga ctttttatta
     1441 tttttagtaa tagctgatgg gttaatactt acaactttcc ttttcaaagt accatataaa
     1501 aaaa
//
LOCUS       DAFBVQ010000160         1498 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.167, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000160 DAFBVQ010000000
VERSION     DAFBVQ010000160.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.167"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            316..570
                     /locus_tag="LLC22_002890"
     CDS             316..570
                     /locus_tag="LLC22_002890"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318299.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AbrB family transcriptional regulator"
                     /protein_id="HBK5436080.1"
                     /translation="MGKELKVRKIGNSVGVILPSSLGLKSGDIIQAKQEDNLFILDTT
                     QIAKEHDRKLIEESFQDFEKGLTVSEIEMVKAFGKYGWSE"
     gene            571..888
                     /locus_tag="LLC22_002891"
     CDS             571..888
                     /locus_tag="LLC22_002891"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002318298.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type II toxin-antitoxin system RelE/ParE family
                     toxin"
                     /protein_id="HBK5436081.1"
                     /translation="MKEYTLVYSKSFQTSLETIIEEWENELALSPASIKRFVGAIQKA
                     LELTKNFPTMHEEVSEIYGMDIPTYRIVIGKSYALFYRIDHEKKEILVGRIFQSKQMK
                     LGF"
BASE COUNT          531 a          228 c          290 g          449 t
ORIGIN      
        1 acaaaataaa aaggcaatac gccttagttg tcggtcttcg agttaccaac ggtaaccctc
       61 ataccgaacg gcattcatca cccacctata gaggatgggc gacttctgcc taattctgtt
      121 aaatggatgt taacggaagt gtatggtgag tagttcactc gtattttgat atcgtttgta
      181 tatgttttca gcgttctaag tggcttattt tgtccaataa taatatggag tggaatccct
      241 taagaaacac cgttggcaat tgttgttata acatgttata atttattcat caaaaactaa
      301 aaggagtgtg ataacatggg aaaagaacta aaggttagaa agatcggcaa tagcgtggga
      361 gtgatccttc caagctctct tggattaaaa agcggagaca ttatccaagc caaacaagaa
      421 gacaacttat tcatattaga tactactcaa atagcaaaag aacacgatcg caaattgatt
      481 gaagaaagtt tccaagactt tgagaaaggt ttaacagttt cagaaattga aatggtaaaa
      541 gctttcggaa aatacggctg gagtgaatag atgaaagagt acacgctagt ttattctaaa
      601 agttttcaga ccagccttga aacgataata gaagaatggg aaaatgagct tgctctttct
      661 ccagccagca taaaaagatt tgtaggtgcg atccagaagg ctttagaact aaccaaaaat
      721 tttccaacta tgcatgagga agtttccgaa atctatggaa tggatatccc aacatatcgg
      781 atcgtgatcg gcaaaagcta tgccttattt tatcggatcg accatgaaaa aaaagagata
      841 cttgtaggac gtattttcca atctaaacaa atgaaactag gcttttaaca ataattagga
      901 aaaagtcgct catcctctac aggtgggtga ttaatgccgc tcgatatggt tgttaaccgt
      961 cggttactcg aagattgata tataagactt agtacctttt tattttgctc catgttatgg
     1021 ccgaaggtct aaagatacaa tcattagtct agagaaaaat taagaacctt aggaactacg
     1081 gggatcgctt ggtgaataag agacactgct attagtgaaa aaataagata tcaagtacgc
     1141 tctattccca aaaatttcgt gactttactc atgagaggtt caagtagtat atttttaatc
     1201 aaaattgacg taacttttaa taaatactac ctaaataagg tagtatttat ttttgtgttt
     1261 taaaagagga agtccaatat atctatggga aacttcttaa atattatgtt ggtacatgaa
     1321 aatatacttc cctgctagac tatttacaac attttacttt gtacgtattc ttgttttaaa
     1381 aggaatggga taaaatatag gtacaataac tatttgatgc taaatataat taatggagga
     1441 gagatagtga acatacttaa tgaaaaaaga tatgtatggt ttgctggtaa aaaatata
//
LOCUS       DAFBVQ010000161         1456 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.168, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000161 DAFBVQ010000000
VERSION     DAFBVQ010000161.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1456)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1456)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1456
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.168"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            108..1040
                     /locus_tag="LLC22_002892"
     CDS             108..1040
                     /locus_tag="LLC22_002892"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002304713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4041 domain-containing protein"
                     /protein_id="HBK5436082.1"
                     /translation="MLKLKEKEYIIDDAVSVPLILNKREKNNLKKKMLIPFDSEVKGL
                     LNKLTISNIDSTREKIIKIFDKINNLFKNDNAELRKGLLEFKLQELELHYSYLVKITE
                     EKEQQKAIKEQMIEEEKVRREIDREKKRIDKEQRQFNSEISKLIAYMQKANADVEKEL
                     YANKIQELEEKLKELEVIRENVLQRELNTRAGYVYVISNIGSFGEDIYKIGMTRRLEP
                     MDRIKELSSASVPFEFDVHAMIFSEDAPSLETKLHNHFRKQEVNKINQRKEFFKVSLD
                     EIEKVVLENYNGTVTFTKLAKAEQYRRSLELSKD"
     gene            1112..>1456
                     /locus_tag="LLC22_002893"
     CDS             1112..>1456
                     /locus_tag="LLC22_002893"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341521.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436083.1"
                     /translation="MWLEKINDKKFKYTERYTDPLTEKKRKVSVTLSSNSRQAWNQAN
                     LLLNEKIAEKIKRNEELPLTFGELKTKWDEKYKPTVKESSYRTTQVYLSLISKYIKDD
                     VLVKNVNSNLIQD"
BASE COUNT          640 a          169 c          227 g          420 t
ORIGIN      
        1 atgaaataaa tcaaaagtat gatgaaacat taaaaaatgt ctattcttca cttatcgttt
       61 caaatataga agaaacttca tcttctgaaa taaaaaataa gctttctttg ttaaaattaa
      121 aagaaaagga atatattatt gacgatgctg tttctgtccc tcttatttta aataaacgag
      181 agaaaaataa tttaaagaaa aaaatgctca ttccatttga ttcagaagtg aaaggattac
      241 tcaataaact aactatttct aatatagact cgactaggga aaaaatcata aaaatatttg
      301 ataaaattaa taatttattc aagaatgaca atgctgaatt aaggaagggt cttttagagt
      361 ttaaacttca agaactagaa cttcattact cttatttagt gaaaattacc gaagaaaaag
      421 aacaacaaaa agcaataaaa gaacagatga tagaagagga aaaagttcgt agagaaattg
      481 atcgtgaaaa gaaacgtatt gataaagaac aacgtcaatt caattctgaa atttccaaat
      541 taatcgcata tatgcaaaaa gctaatgcag atgtggaaaa agaattatat gcaaataaaa
      601 ttcaagaact ggaagaaaaa ttaaaagaat tagaagttat acgtgaaaat gtattacaaa
      661 gagaattaaa tactagagcc ggttatgtgt atgtaattag taatattggg tcttttggtg
      721 aagacatata taaaattggt atgactagaa gattagaacc tatggataga ataaaagaat
      781 tgagtagtgc atcggttcca tttgaatttg acgttcatgc gatgattttt tcagaggacg
      841 ctccgtcttt ggaaactaaa ttgcataatc attttagaaa acaagaagtt aataaaatta
      901 atcaaagaaa agaatttttc aaagtttcac tagacgaaat agagaaagtt gttttagaaa
      961 attataatgg aacagtaaca tttacaaaat tagctaaagc tgaacaatat agacgatctt
     1021 tagaattgtc aaaagattaa atatataaaa agccttcggg ctttttcttt taacaattaa
     1081 taggaacgta tattcgaaag gaatagaaat aatgtggtta gaaaaaataa atgacaaaaa
     1141 atttaagtac accgaacgtt atacggatcc cttaactgaa aaaaagagaa aagtgtccgt
     1201 tactttatct agcaattcac gccaagcttg gaatcaagct aacttacttt tgaatgaaaa
     1261 aatcgcagaa aaaataaaac gaaatgaaga attaccacta acttttggag aattaaaaac
     1321 taaatgggat gaaaaataca agccaactgt aaaagaaagt tcctatcgaa caactcaggt
     1381 ttatctatca ttaatttcaa aatatataaa agatgatgta cttgtaaaaa acgttaatag
     1441 taatcttata caagat
//
LOCUS       DAFBVQ010000162         1424 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.169, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000162 DAFBVQ010000000
VERSION     DAFBVQ010000162.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1424)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1424)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1424
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.169"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(150..1337)
                     /locus_tag="LLC22_002894"
     CDS             complement(150..1337)
                     /locus_tag="LLC22_002894"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296840.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element IS16 family transposase"
                     /protein_id="HBK5436084.1"
                     /translation="MTQVHFTFESEEIQAIINESGANDTAKTLMTIMFNQLMEEQRNQ
                     YIQANAYERSEERQSQRNGYYDRSFTTRIGTLELHVPRTRDGKFSPTIFERYQRSEKA
                     LIAAMIEMVISGVSTRKVTKTVELLTDGATVSKSFVSNLMKQLDPFVFEWRNRSLEGS
                     EYPFFMCDALYMKVRENHRIVSKGVYIGIGIDSDGRRTILGFDVQDGESEDNWDTVFQ
                     SFVQRGLFGVKLVISDAHKGLVKAVRKNFLGASWQRCQAHFLRNIFDKLPKKVSSDVK
                     DELKSIFKASELELTRERKEHFLEKYGCDSKLSAACDILENGFEDAIQILSFPENIRR
                     RIRTTNVLERLNEEIRRRERVIRIFPNINSITRIIGTLLMEKDTEWLASPRKYLEFNS
                     NNI"
BASE COUNT          414 a          309 c          249 g          452 t
ORIGIN      
        1 taaaagttca acctcatcaa aagcacaatg ttttgcgttg tgaacctaac tgccatgcct
       61 ttctttctga ggagagaggt caggagcagt agcgcagcga ctcttgatgt ctctcctcag
      121 aaagaagaga ctcgcacagg ttcatggtgc taaatgttat tcgaattaaa ttctaaatat
      181 tttcgtggag aagccagcca ctcagtgtct ttttccatca aaagtgttcc aattatccga
      241 gtgatggaat tgatatttgg aaaaatccga atcactcgtt ctctccggcg aatctcttcg
      301 ttcaaccgtt ccaacacatt ggttgtacga atccttcggc ggatattttc aggaaaagac
      361 aaaatttgaa tagcatcttc aaagccgttt tctaaaatgt cgcaagcagc acttaatttt
      421 gaatcacaac catatttttc caagaagtgc tcttttcttt cacgtgtcaa ttcaagttca
      481 gaggctttaa agatactctt caactcgtct tttacatcag aagaaacttt ctttggcagc
      541 ttatcaaaaa tatttctcaa aaagtgggct tggcatcttt gccagctcgc acctaaaaag
      601 ttcttgcgaa cagccttaac taaccctttg tgtgcatcag aaatgaccag ttttacaccg
      661 aacaaacctc gttgaacgaa cgattgaaaa acggtatccc aattatcttc cgattcgccg
      721 tcttgaacat caaaaccaag aatcgtacgt cgtccatcag aatcaatgcc gataccaata
      781 tatacacctt ttgagacaat acgatgattt tcccttactt tcatatacag ggcatcacac
      841 atgaaaaatg gatattccga gccttctagg ctccggtttc tccactcaaa aacaaatgga
      901 tccaactgtt tcatcagatt tgaaacgaat gatttagaaa cagtcgcacc atccgttagc
      961 agttcaactg ttttagttac tttgcgagtg gagacaccag aaatgaccat ttcaatcatg
     1021 gcagcgatca aagctttttc gcttcgctga tatctttcaa agatagtagg actaaactta
     1081 ccgtctctgg ttcgtggaac atgaagttct aacgtaccaa ttcgagttgt aaacgaacga
     1141 tcgtagtaac catttctttg tgattgccgt tcttctgaac gttcataggc atttgcctga
     1201 atatattgat ttcgttgttc ttccatcagc tgattaaaca tgatagtcat aagtgttttt
     1261 gcggtatcat tcgcaccgct ttcgtttata attgcttgaa tttcttcgct ttcaaaagta
     1321 aaatgtactt gagtcattga tatcagtcct attcgagtat gttttctgca aaaaacattg
     1381 tactcctaac tgagatcaat ggcttttttg atgcttcact ttta
//
LOCUS       DAFBVQ010000163         1423 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.170, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000163 DAFBVQ010000000
VERSION     DAFBVQ010000163.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1423)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1423)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1423
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.170"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            98..1390
                     /locus_tag="LLC22_002895"
     CDS             98..1390
                     /locus_tag="LLC22_002895"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016628567.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5436085.1"
                     /translation="MSYTHLIKETLDILDLSVTFNENCLTKEKYKGQICHIYRGNLIY
                     TAQECIHCKHQIASDIVRWGTTTVRLLMNDVSEYRTYLELKKQRFKCKACQRTFVADT
                     SVAKKHCFISEKVRWSVVTRLKKNTSMTEIAAQKNLSVSSVYRIMKRFYRPLNPFRTP
                     LPKVLCFDEFKSVRGVSGAMSFIMMDGQTQRLLDIVENRQLPFLKRYFSHFSREIREA
                     VEWIVIDMYAPYVSLVKKLFPKAQLIIDRFHIVQHIGRTFRNHRIKETNQLLKSKEQK
                     HYQLGKQLKRYWKLLQKDERKLDYTRRLWRPGFKAHLTETDIVDRLLKGSPALRVGYQ
                     LYQDFLYAVKERDYVSFEELLTNNIMLPEGYQTTLRTFQKFLPQIKNALQQSYSNGPL
                     ECLNNHIKVLKRNAYGFRSFYNFKLRIMIRHGNALIFN"
BASE COUNT          463 a          292 c          257 g          411 t
ORIGIN      
        1 acaccagcat cttttttatt ttccaaaaca tatagaaaag acaccttgaa atcctttaga
       61 attaatttgg cgaaccaacc caaaaggagg aatcaagatg tcttacactc accttatcaa
      121 agaaacatta gatattctag acttatcagt tacttttaac gaaaattgtc tcacaaaaga
      181 aaaatacaaa gggcaaatct gtcatattta tcgtggaaac ttgatttata cagcccaaga
      241 atgcatccac tgtaaacacc agattgcttc agatattgtg cgttggggta caacaaccgt
      301 ccggttgtta atgaacgatg tttctgaata ccgtacctac ctcgaattga aaaagcaacg
      361 cttcaaatgc aaagcttgtc agcggacctt tgtcgcagat acttctgttg cgaaaaaaca
      421 ttgtttcatc agtgagaaag tccgctggtc tgtcgtgact cgtctgaaaa aaaatacctc
      481 aatgacagag atcgccgctc agaaaaatct atcggtctct tctgtttacc gtattatgaa
      541 gcgattttat cgtccgttga atccttttcg gacaccgtta cctaaggtac tttgttttga
      601 tgaattcaaa tcagttcggg gtgtttcagg tgctatgagt ttcatcatga tggatggaca
      661 aacacagcgc ttattggaca ttgtcgagaa ccgacaactg ccttttttaa aacgttattt
      721 tagtcatttt tcacgagaaa ttcgtgaagc ggtcgaatgg atcgtgattg atatgtacgc
      781 tccttatgta tcgctcgtta aaaagctgtt tccaaaagca cagctgatta ttgaccggtt
      841 tcacatcgtc caacatattg gtcgtacctt tcgcaatcat cgaatcaaag aaacgaacca
      901 actattaaaa agcaaagaac aaaaacacta tcaattaggt aagcaattaa aaagatactg
      961 gaaacttctt caaaaagatg aacgcaagct tgattatact cgacgccttt ggcgacctgg
     1021 cttcaaagct catttaacag agaccgatat tgtggatcgc ttactgaaag ggagccctgc
     1081 tttgcgtgta ggctatcagt tatatcaaga ctttctttac gctgtaaagg aacgagacta
     1141 cgtatcgttt gaagaactac ttaccaataa tatcatgctt cccgaaggct atcagacgac
     1201 cttgagaacg ttccagaaat ttctgccaca aatcaaaaat gctttacaac aaagttattc
     1261 aaatggccca cttgaatgtc tgaacaacca tatcaaagtg ttaaaacgaa atgcatatgg
     1321 ctttcgtagc ttttataatt tcaaattgcg catcatgatt cgtcatggca acgcattgat
     1381 tttcaactaa aaaagatcaa gaggaactga tccacttgat ctc
//
LOCUS       DAFBVQ010000164         1406 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.171, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000164 DAFBVQ010000000
VERSION     DAFBVQ010000164.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1406)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1406)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1406
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.171"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(182..255)
                     /locus_tag="LLC22_002896"
     tRNA            complement(182..255)
                     /locus_tag="LLC22_002896"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:complement(219..221),aa:Ile,seq:cat)
     gene            complement(444..1403)
                     /locus_tag="LLC22_002897"
     CDS             complement(444..1403)
                     /locus_tag="LLC22_002897"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016249812.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="peptidoglycan recognition protein"
                     /protein_id="HBK5436086.1"
                     /translation="MNGFAYTINNEFNLGANEGSSQVANNQYILLHETANETATGRNE
                     AQYMQRSWTSAYTAYIVGDGGIVYQVGQPGYVQYGAGSYANANSPVQIELQHTHDKAT
                     FEKNYKAYVELARDSAMKYGIPLTLDTPYNQPGIKSHLWVTQNIWGDHTDPYGYLSEM
                     GVSKEKLAYDLAHGFTDENPTTSENKPVIDPTRAGAANPTLTDGTNYAHIDQFGEIEN
                     ANLHVAGWHIANYKYEYIFIMDYNTGKELARVRADGIYRSDVNQAYNTSGNVGYHVSF
                     NMRNFPNKKVYVMMRATNDPEGNTKGGAQDFHDKRWYLNIPKR"
BASE COUNT          416 a          279 c          255 g          456 t
ORIGIN      
        1 taaaaatcaa agtaaaactt ttcaaatata cagaaatata actatgtgaa acatcctttc
       61 attaatccat aaaaggatac ataaaaaagc cactcatttg agtggcaatg aagaaaagct
      121 ttagcttgta taatactctt caaaaaattc taacacagaa cgattcaaat ggctacgtta
      181 atgtaccctg taggactcga acctacgacc ggacggttat gagccgtctg ctctgaccaa
      241 ctgagctaag ggtactggtt gttgccacat aaagccataa acaatcaacc agtagaatgt
      301 gtggcaacaa acctgttatc gcatagcttg gagtgtgact attatgggtg atagtgaaga
      361 tatgcgataa catcactatt ttatcgaatg atttttatag ttgtcaatat agttatgtaa
      421 tgctcctcaa cgaggagcta tttttatcgt ttaggaatat ttaaatacca acgtttgtca
      481 tggaaatctt gcgcaccgcc tttagtgttt ccctctggat cattcgttgc ccgcatcatg
      541 acatagactt tcttattagg gaagttacgc atgttaaaag atacatgata gccaacattt
      601 ccagaagtat tataagcttg atttacatct gatctataaa ttccatcagc tcttactcga
      661 gctaattctt tcccagtatt gtaatccata atgaagatat actcgtattt atagttagca
      721 atgtgccatc cagctacatg caaatttgca ttttcgattt ctccaaactg atcaatgtgg
      781 gcgtaattcg ttccatctgt cagtgtagga ttagctgcac cagctcgtgt tggatcaatg
      841 acaggcttgt tttcagaagt tgttggattt tcatcggtaa atccatgagc taaatcatat
      901 gctaattttt ctttacttac gcccatttca gaaagataac cgtaaggatc tgtatgatcg
      961 ccccagatgt tttgtgttac ccataaatgc gatttgattc ccggttggtt ataaggagtg
     1021 tccaacgtta atggaatacc atatttcatt gctgaatctc tagccaattc aacgtatgcc
     1081 ttgtagtttt tctcaaacgt tgctttatca tgtgtgtgtt gtaactcaat ctgcacagga
     1141 ctgttggcat tagcatacga accagcaccg tactgtacat aaccaggttg accgacttga
     1201 taaacaattc cgccgtctcc cacaatataa gcagtataag cgctagtcca tgaacgttgc
     1261 atatactgcg cttcattgcg tcctgttgct gtttcattag ccgtttcatg cagtaaaata
     1321 tactgattat ttgctacttg tgagctacct tcatttgcgc ccaaattaaa ttcattgttg
     1381 atagtatagg caaatccgtt aattgg
//
LOCUS       DAFBVQ010000165         1380 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.172, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000165 DAFBVQ010000000
VERSION     DAFBVQ010000165.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1380)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1380)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1380
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.172"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..650
                     /locus_tag="LLC22_002898"
     CDS             <1..650
                     /locus_tag="LLC22_002898"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002371169.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="aminotransferase class V-fold PLP-dependent
                     enzyme"
                     /protein_id="HBK5436087.1"
                     /translation="GYLLCLKRLRVEQAVVVEDSPVGAQAAPHMTVDVQALDADFFAF
                     SGHKMCGPTGIGVLYGKRQLLEQMEPVEFGGEMIDFVNLYDSSWKELPWKFEAGTPNI
                     AGAIDYLNEIGMENIHRYEQELVAYVLPKLQAIGGITIYGPQDPEHHTGVVAFNLDGI
                     HPRDVATALDMEGVAVRSGHHCAQRFIDDFCLTNWSFKQSMIMPFERLQCRGIFE"
     gene            complement(552..1072)
                     /locus_tag="LLC22_002899"
                     /pseudo
     CDS             complement(552..1072)
                     /locus_tag="LLC22_002899"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340466.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT          395 a          244 c          308 g          433 t
ORIGIN      
        1 aaggttattt gttgtgcttg aaacggctga gggttgaaca ggctgttgta gttgaggata
       61 gtccagtcgg tgcccaagca gcaccgcata tgacagttga tgtacaagcg ttggatgcag
      121 attttttcgc ctttagcggg cataaaatgt gcgggccgac aggaatcggt gtattatatg
      181 gcaaacgtca attgttagaa caaatggagc cagtcgaatt cggcggtgaa atgatagatt
      241 ttgtcaatct ttacgatagt tcatggaaag agctgccatg gaaatttgaa gctggtactc
      301 cgaacattgc aggagcaatc gattacttga atgagattgg tatggagaat attcatcgtt
      361 atgagcaaga actggttgcc tacgttttac ctaaattaca agcgatcggc ggtatcacca
      421 tttacggacc gcaagatcct gaacatcata ctggcgtggt tgcttttaat ttggatggca
      481 tccatccccg tgatgtggcg actgctctgg atatggaagg tgtcgctgta cgttcaggac
      541 accattgtgc acaacggttc atcgacgatt tctgtttgac taattggtcg tttaaacagt
      601 cgatgataat gccgtttgag cggctccaat gtcgtggaat ctttgagtaa gagtttccaa
      661 tatcgcttga gccgacggta cttcttctga ttttcagatt acgtgattga ttttcgtaca
      721 gttctatgag aatcgcctgc ttcagttcct ttgttagttg atgatgttca tcaactaagt
      781 ccgttttcgc agaaaaggtc tgcccacaat catagcatag aaaacgggta cgttttaatt
      841 ctaaaatagt caacttttct ttgactttca acatctgagt acgtgtcgta taggaaccgt
      901 tgcggataat acgaatcgat ccacagtgtt cacaatggga aggtgagtca tccaatctcc
      961 ctttaataaa ctgcgcttga acgcctttat attctttttc aatcagccat tcttcatcaa
     1021 aaaataaatg tttatctgtt aatccgagta attttctagt atgattatcc atagagcgac
     1081 tcctttggta gggtgatgtt ttggtcgact aaattttacc aaaagtgagt ctctttttga
     1141 gttgaaacga agaaaaagtg ttagtagaaa atcgccttcg attttccaac aacacaaaat
     1201 attatagaag ccttttttct aaaggatttc aaggtgtctg tttgcattta ttaaaaaaaa
     1261 gaaaaagtat tggcaacaga aggcgtcacc aacactagat attatagagc cataatatgc
     1321 tgtataatat ctagtgtata ggcttaagtg gaggtatata tgaaaatatt aactgttgaa
//
LOCUS       DAFBVQ010000166         1366 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.173, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000166 DAFBVQ010000000
VERSION     DAFBVQ010000166.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1366)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1366)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1366
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.173"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            31..1332
                     /locus_tag="LLC22_002900"
     CDS             31..1332
                     /locus_tag="LLC22_002900"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002351973.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5436088.1"
                     /translation="MPDLHHIKLLLGIKDKNIFITNVESKSIKNIKSLVVSATLSKEI
                     RRCPLCKQMNHEGMIVKNGKKKSLIQLNKCANQLTYLALAKQRYHCRGCHTYFTANTY
                     IVDRNCFIAKQVRYKILEELTEKQAMTTIAKHCGVSWSTVSRTLASLIPMTKVKRNWL
                     PRCLLMDEFRSLKNQVGPYSFSCMDGDTGKLLDILPSRKKKALVSYFMQFERRARLKV
                     KVIVTDMNVSYASLIKECFPKAKLVVDRFHIVKHLIRKFEDIRVRIMKSFDRNDPTQA
                     KYYRQLKALSRLLIKRQDKLVYDKWTKWRNFGWAYLTESEVVDRLLSISDELRIAYFY
                     YQEILQAFHDKEADTFFKLVRTMPNSVPKELHSIKKAFINYESGIRLALELPYSNAKI
                     ENLHTHIKALKRVAYGFRSFRKMKTRIFLLNNLITYESKNI"
BASE COUNT          444 a          275 c          252 g          395 t
ORIGIN      
        1 caccacaaca caatcaaagg agcgttctgt atgcctgatc ttcatcatat caaactacta
       61 cttggaatca aagataaaaa cattttcatc acaaatgtgg aatcgaagag cattaagaat
      121 atcaagagtc ttgttgtttc tgcgacgtta agtaaagaaa ttcgtcgctg tcctttgtgt
      181 aaacagatga atcatgaagg catgatcgtt aagaacggaa agaaaaaatc gctcattcaa
      241 cttaataaat gtgcgaacca actgacttat cttgctttag cgaaacaacg ctaccactgt
      301 cgtggctgcc acacctattt tacggcgaat acctacattg tcgatagaaa ctgctttatc
      361 gctaaacaag tgcgctataa aattttagaa gagctaactg aaaaacaagc aatgacgaca
      421 attgctaagc attgcggcgt ttcttggtcg accgtttctc ggacactcgc ttctctgatc
      481 cccatgacaa aagtaaaaag aaattggtta ccgcgttgtt tattaatgga tgaatttcgt
      541 tcactgaaaa atcaagtcgg tccctactcc ttttcttgta tggatggcga tactggaaaa
      601 ttactggata ttcttccttc acggaagaaa aaggctctcg tttcttattt tatgcaattt
      661 gaacgacgcg cacgattgaa ggtaaaggtc atcgtgacgg acatgaatgt ttcttatgcc
      721 tctctgataa aggaatgttt tccaaaggca aaactcgttg tggatcgttt tcacattgtc
      781 aaacatctca ttcgtaaatt tgaggatatt cgcgtacgaa tcatgaaaag ctttgatcga
      841 aacgatccaa cacaagccaa atattatcga caattaaagg cgttgtctcg gcttctgatc
      901 aaacgacagg acaagcttgt ttatgacaaa tggaccaaat ggcgcaattt tggttgggcg
      961 tatctcaccg aaagtgaagt ggtggatcgt ctgctttcga tctctgacga attacgaatc
     1021 gcctattttt actatcaaga aattcttcaa gcgtttcacg acaaagaggc ggacactttc
     1081 tttaaacttg taagaacgat gcccaattcc gttccaaaag aactgcattc tataaaaaaa
     1141 gcttttataa actatgaatc cggcattcgt ttagccctcg aattgcctta ttcaaatgcc
     1201 aaaatagaaa atctgcatac ccacatcaaa gcattgaaac gagtcgctta tggctttcga
     1261 agctttcgga aaatgaagac cagaattttc ttactaaata atctgattac ctatgaatca
     1321 aaaaacatct aaagtagaaa aggaattcta ccttagatgt tcttat
//
LOCUS       DAFBVQ010000167         1364 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.174, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000167 DAFBVQ010000000
VERSION     DAFBVQ010000167.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1364)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1364)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1364
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.174"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            82..>1364
                     /locus_tag="LLC22_002901"
     CDS             82..>1364
                     /locus_tag="LLC22_002901"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa11 family transposase"
                     /protein_id="HBK5436089.1"
                     /translation="MNDSIKKMLRITEKDLMITEVSYETLQKKKTLVVDAVLSPTPRA
                     CRSCGSTVVDGNGKAIIVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKSCQVSLTTVIRTLKEFKSYLPKQSK
                     KILPRVLMVDEFRSHASIEDKMSFICADGETGKLIDVLPTRKLPRLTSYFLGCTNPEE
                     VEFLVTDMNAAYFQLTKRVLPNAKVVIDRFHIVKHMNQAFNELRIREMNELRKAGQKS
                     QAEKLKKNWRFLLKNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLEFSPPLKEAY
                     PFFHELVEAFRDKDPDLFFSLLAELPETLDDSFREKLQNLLTYEEGITNAMIYPYSNG
                     KIEAKNTHIKTMKRVSYGFKSFENMRIRIFLINQL"
BASE COUNT          465 a          262 c          257 g          380 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcaccac aaaataaaca
       61 actgagagga cgatacgcta tatgaatgat tctatcaaaa aaatgctgag aataacagag
      121 aaagatttga tgattacaga ggtctcttac gagacccttc agaagaaaaa gacgttggtc
      181 gtcgatgctg ttctctcgcc tactcctcgt gcttgtagaa gttgtggttc tactgtggta
      241 gatggaaacg ggaaagcaat tatagtgaaa aatggaaaaa aggaaacgat tgtccgtttt
      301 gaacaataca atcatatgcc tttggttatg cgcctaaaaa agcaacgcta tacctgtaaa
      361 aactgtcgca cccattggac ggctcaaagt tattttgtcc aacccagaca ttcaatcgca
      421 aatcatgtta gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaagct gtcaggtatc tttgaccacc gttattcgta cattgaaaga gtttaaaagc
      541 tatttaccaa agcaatctaa gaagatcctc cccagagtat tgatggttga cgaatttcgt
      601 tcgcatgctt ccatagaaga taagatgagc tttatttgcg cggatggcga aacaggaaaa
      661 ttaatagatg ttttgcctac gcgtaaatta cctcgattaa caagctattt cttaggttgt
      721 accaatccag aagaagtaga attcttggtg acagacatga acgccgccta cttccagctc
      781 accaaacgtg ttctgccaaa tgcgaaagtc gtgattgatc ggtttcatat tgtcaaacac
      841 atgaatcaag cgttcaatga gttgcgtatc cgtgaaatga atgaacttcg taaagccgga
      901 cagaaaagcc aggcagaaaa actgaaaaag aactggcgct ttttgctaaa aaatcgtgca
      961 aacatcaacc attatgaata caaaacatgg aaaagtttcc gagcaccaaa atacccattt
     1021 cttactgaag caatgatgat tgatcgattg cttgagtttt ctccgcccct aaaggaggcg
     1081 tatccctttt ttcatgaatt agttgaagcc tttcgagaca aagaccctga cttatttttc
     1141 tccttattgg cagaacttcc cgaaacgtta gatgacagct ttcgggaaaa gcttcaaaac
     1201 cttctgacct atgaagaagg catcaccaac gcaatgatct atccttattc caatggaaaa
     1261 atagaagcga agaataccca cataaagaca atgaaacgag tatcctacgg atttaaatca
     1321 tttgagaaca tgagaattag aatctttttg atcaatcaat taat
//
LOCUS       DAFBVQ010000168         1352 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.175, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000168 DAFBVQ010000000
VERSION     DAFBVQ010000168.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1352)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1352)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1352
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.175"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            11..1350
                     /locus_tag="LLC22_002902"
     CDS             join(11..452,452..1350)
                     /locus_tag="LLC22_002902"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611105.1"
                     /ribosomal_slippage
                     /note="programmed frameshift; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element ISEnfa3 family transposase"
                     /protein_id="HBK5436090.1"
                     /translation="MRKYTFVFKKKVVSDYLNNEGGYKYLAHKYQINRTLVRHWVRIY
                     NYHGWEGLVGGGKSYTTKFKLDVIEYMETNGLSIQETAKKFNIGSNRTLSKWIEQYEE
                     GGASSLESQKRGRKISMNSKLNIPKKLKDESLEEEVIRLRAENAYFKKVRNLDSRTRF
                     EQEEIKVKTILQLKKEFKLNLLLSIAQLAKSTYYYWVKKLDKPDKYSKIKQEITAIVK
                     ESRNSYGYRRVTLALKMKGYTINHKTVRKLMSQMGLTCQIRIKRYKSYKGTVGKIAKN
                     VLKRNFSVDTPNKKWVTDVTEFKIKGRKIYLSPILDLFNGEIISYSISTSPTYKLIEE
                     MLQQAIKKKGTEGSLILHSDQGWQYQMPQYQKKLKENNIIQSMSRKGNCLDNSVIENF
                     FGVLKSEFFYREKFRSIEIFQSKLNEYIRWYNNKRIKLKLNGLSPVEYRKQSIK"
BASE COUNT          565 a          175 c          235 g          377 t
ORIGIN      
        1 ggtgcttttt ttgcggaaat atacatttgt ttttaagaaa aaagtagttt cagactattt
       61 aaataacgaa ggcggctaca aatatcttgc acataaatat caaataaatc gtacactggt
      121 tagacattgg gtaaggattt ataactatca tggttgggaa ggcttggttg gaggtggcaa
      181 aagctacact acaaaattta aacttgatgt tatagaatat atggaaacaa atggtctttc
      241 tatccaagaa actgctaaaa aatttaatat cggttcaaat agaactctaa gtaaatggat
      301 agagcaatat gaagaaggcg gtgcttcttc acttgagagc caaaaaaggg gcagaaaaat
      361 tagtatgaat tccaagctaa acattcctaa aaaacttaaa gatgagtctc ttgaagaaga
      421 agttattcgt ttaagagcag agaacgcata tttaaaaaag ttagaaacct tgattcaaga
      481 acaagatttg agcaagaaga aatcaaggtt aaaacaatcc ttcagctcaa aaaagaattt
      541 aaattgaatc tattactttc aattgcacaa ttagcgaagt caacttatta ttactgggta
      601 aaaaaattag ataagccaga taaatatagc aagataaagc aagaaattac agcgattgta
      661 aaagaatcaa gaaactctta tggttatcgt agagtcactt tagcgttaaa gatgaaagga
      721 tatacaatca atcataaaac agttagaaaa ttaatgtccc aaatgggact tacctgtcaa
      781 atccgaataa agcgatataa atcttataaa ggaacagtag gaaaaattgc caagaatgtg
      841 ttaaaacgaa atttttcagt agatacaccc aataaaaaat gggtgacaga cgtcactgaa
      901 ttcaagataa aaggaagaaa aatctatcta tctcctatac ttgatttatt taacggagaa
      961 ataattagtt atagtatatc aactagtcca acatataaac tgattgaaga aatgcttcaa
     1021 caagcaatta aaaaaaaggg aactgagggt tcactgattc tacattcaga tcaaggatgg
     1081 cagtatcaga tgccacaata tcaaaaaaaa ttaaaagaga ataacattat tcaaagcatg
     1141 tctagaaaag gaaattgctt agataattct gtaatagaaa atttttttgg tgtgcttaaa
     1201 tcagagtttt tttatcgaga aaaattccga tcaattgaga tatttcaaag taaattaaat
     1261 gagtatatta ggtggtataa taacaaaagg ataaaactaa agttaaatgg actatctcca
     1321 gtagaatatc ggaaacagtc cattaaatag tt
//
LOCUS       DAFBVQ010000169         1338 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.176, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000169 DAFBVQ010000000
VERSION     DAFBVQ010000169.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1338)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1338)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1338
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.176"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            15..1310
                     /locus_tag="LLC22_002903"
     CDS             15..1310
                     /locus_tag="LLC22_002903"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016252604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
                     /protein_id="HBK5436091.1"
                     /translation="MSHTQLIKDTLNILDLNIYFEENCLTKEKYKGQICLIYKGTLLY
                     KPEECSHCLCVVPSRIIRWGTTTVRLLLNDVSEYRTYLELKKQRFKCKSCQRTFVADT
                     SVAEKHCFISQKVRWSVIARLKENTSMTEIARQKNISTSSVYRVMKRFYRPLNPFKQT
                     LPKVLCFDEFKSVRSVASAMSFIMMDGQSHALLDIVENRRLPYLERYFSRFSLATREA
                     VQLIVIDMYAPYVSLVKKLFPNAQLIIDRFHIVQHIGRTFLNHRVKETTVRLKGNSHS
                     QRGLGKKLKRYWKLLQKEEAKLNYEKRVWRASFKDYLTESEIADRLLAACPNLRQGYQ
                     LYQDILYAVKKRDQSLFEDCLTRDISGLPETYTTTLRTFKKFLPQIQNALHYSYSNGP
                     LECLNNHIKVLKRNAYGFRNFYNFKLRIMIRHGKTFLTK"
BASE COUNT          418 a          265 c          258 g          397 t
ORIGIN      
        1 taggaggatt caagatgtct catactcagc ttatcaaaga taccctaaat attctagacc
       61 taaatatcta tttcgaggaa aattgtttaa ctaaagaaaa atacaaaggg caaatttgct
      121 tgatttacaa aggaactctt ctgtacaagc cagaagagtg ttcccattgt ctttgtgtcg
      181 tcccctctag gatcattcgt tgggggacga caaccgttcg gttgttactg aatgatgtgt
      241 ctgagtatcg cacttatctg gagctgaaga aacaacgatt taaatgtaag tcttgccaaa
      301 gaacattcgt agcggatacc tctgttgctg aaaaacactg tttcattagt caaaaagttc
      361 gttggtctgt cattgctcgc ttaaaagaga atacttccat gacggaaatc gctcgtcaga
      421 aaaatatttc cacttcttcg gtctatcgtg tcatgaagcg attctaccgc ccattgaatc
      481 ctttcaaaca gactttgcca aaggtcttat gctttgatga attcaaatcg gttcgaagtg
      541 ttgccagtgc aatgagtttt atcatgatgg acggacaaag ccatgcatta ttggatattg
      601 tcgaaaatcg acgcttgcct tatttagaac gctatttttc tcggttttca ttagcgactc
      661 gtgaagccgt tcaattgatt gttattgata tgtatgcgcc ttatgtttcg ttggtgaaaa
      721 agcttttccc gaatgctcag ttgatcatcg atcgtttcca catcgtccaa catattggca
      781 gaactttctt gaatcatcga gtgaaagaaa ccacggtacg acttaaagga aattcccact
      841 ctcaacgagg gttagggaaa aaattgaagc gctattggaa actcctacaa aaagaagaag
      901 caaagttaaa ctatgaaaaa cgggtttggc gtgccagttt taaagattat ttgactgaaa
      961 gtgagattgc cgatcgactg ttagctgctt gtcccaactt acgccaaggc tatcagttat
     1021 accaagacat tctttatgcg gtaaagaaaa gagatcagtc actatttgag gattgtttaa
     1081 ctagagacat tagcggtctg ccagaaacct atacaaccac tttacgaacg tttaaaaagt
     1141 ttctgccaca gatccaaaat gcgcttcact acagctattc aaacggacca ttggaatgct
     1201 taaacaacca catcaaagta ttaaaacgca atgcgtacgg ctttcgcaac ttttacaatt
     1261 tcaaactacg aattatgatt cgtcatggca aaacattttt aaccaaataa acagaacaga
     1321 aagaggtttt cttctttc
//
LOCUS       DAFBVQ010000170         1308 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.177, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000170 DAFBVQ010000000
VERSION     DAFBVQ010000170.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.177"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            241..314
                     /locus_tag="LLC22_002904"
     tRNA            241..314
                     /locus_tag="LLC22_002904"
                     /product="tRNA-Ile"
                     /inference="COORDINATES: profile:tRNAscan-SE:2.0.7"
                     /note="Derived by automated computational analysis using
                     gene prediction method: tRNAscan-SE."
                     /anticodon=(pos:275..277,aa:Ile,seq:cat)
     gene            694..855
                     /locus_tag="LLC22_002905"
                     /pseudo
     CDS             694..855
                     /locus_tag="LLC22_002905"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326507.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="DNA repair protein"
     gene            1005..1205
                     /locus_tag="LLC22_002906"
     CDS             1005..1205
                     /locus_tag="LLC22_002906"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_003234247.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5436092.1"
                     /translation="MENGTVKWFNAEKGFGFISREDGSDVFVHFSAIQGDGFKTLEEG
                     QAVTFDVEESDRGPQAANVVKA"
BASE COUNT          419 a          207 c          267 g          415 t
ORIGIN      
        1 ttttttgctc tgtaattaac tcgtatagat cctgcaagat agtttgtttc tgaataaatg
       61 attgatatga agtatttaga tgactgtatt gacaactata aaaatcattc gataaaatag
      121 tgatgttatc gcatatcttc actatcaccc ataatagtca cactccaagc tatgcgataa
      181 caggattgtt gccacacctt ctactggttg attgtttatg gctttatgtg gcaacaacct
      241 gtactcttag ctcagttggt cagagcagac ggctcataac cgtccggtcg taggttcgag
      301 tcctacaggg tacataattt aatctatttg ataaaaaata aaattcaata atggtataat
      361 aaaatgtcgg ctcgtcgctt ccacagagat tttcgtggga ggaggtgtat gatttgtttg
      421 aattcacttt ggagcacgtg ctcttgccat tgttaattgg tttaactttg gcattattta
      481 gtcattggct agataaacat tagagccgac aatggcgctt actgtttcgc agcggtaagc
      541 gtcttttttt gaaaaagaaa aaaacacaac gtattcgcag gtacgttgtg tttatggtgt
      601 atatttgttt aaattcactt tcaattatta ttatacttgt taaataaatt gtgtcaatat
      661 aaaagatatt tttatacgtg tactaaccta tattatcctt ctggtaatgt tattccatcg
      721 cagcaggata tgaattttac caaaaggata caaaagtgtg gagaaatgat ggggatcact
      781 gtactggacc acttgatcat cggacgcaaa cgatatttta gtttgagaga agaaggaatg
      841 atggaagaga agtaagttgc tttcttgcaa aaaaaatgaa gcaagtgtac aattatattg
      901 taattttgtt tgggaataga agttgaaaca tctgttgcac ctctatcgta cacgagcaat
      961 gttacaattt aaattagtgc ttttggcacg aggaggatat tattatggaa aacggaacag
     1021 taaaatggtt caacgctgaa aaaggatttg gatttatctc acgtgaagat ggaagcgacg
     1081 tattcgttca cttctcagct atccaaggtg acggattcaa aacattagaa gaaggtcaag
     1141 cagtgacttt cgacgttgaa gaatcagacc gcggcccaca agctgcaaac gttgtaaaag
     1201 cttaatttta tctgtaaatc aaattgatgg tagacatcaa tttttacgag agaacaaagc
     1261 gagtaacaaa aatacctgcc acaagagaca atttctcttg tggcaggt
//
LOCUS       DAFBVQ010000171         1294 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.178, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000171 DAFBVQ010000000
VERSION     DAFBVQ010000171.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1294)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1294)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1294
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.178"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..1244
                     /locus_tag="LLC22_002907"
     CDS             <1..1244
                     /locus_tag="LLC22_002907"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303202.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS66 family transposase"
                     /protein_id="HBK5436093.1"
                     /translation="ITEKEHLLPLEEQFCEHCGSQMKDIGRTKVREEIRFHQAMLDCL
                     THYQHTYCCKSCEKEGLSSFKKAIVPKPLISNSLGSNSLVAETIRMKFGQKVPAYRQE
                     NYWKQTHGLDISRDNITNWHIKAVQNALDPLGERLRVYLNQEEILHGDETSYRVIESA
                     KTDTYYWQFCTGKDSQHPIVYYHHDESRAGDVPKTFLKEFTGYLHCDGYSGYNAVESV
                     RLVYCFAHVRRKFFEAIPKGKKNTDIPAAQAVKQLDKWFVLEKKWKDFSPEKRLSCRQ
                     QELRPLFIAFYEWMATIDPVAKSKLDAAVQYACKLRSGFEPIFEDGRLELTNNRAERN
                     IKELVIGRKNWLHSTSLEGARTSGIILSVYKTAELNGLNPVKYLEFLFDKIPNLPVLS
                     AETLDQLLPWNKDVQQHFSRN"
BASE COUNT          423 a          233 c          277 g          361 t
ORIGIN      
        1 ctataacaga gaaagaacat ctccttcctt tggaagaaca attttgtgaa cattgcggtt
       61 cacagatgaa agatatcgga cggacaaaag tacgagaaga aattcgtttc catcaggcta
      121 tgttggattg tctcacccat tatcaacata cctattgttg taaaagctgc gaaaaagaag
      181 gactttcttc ttttaaaaaa gcgatcgttc ctaaaccttt gatttctaat agcttaggtt
      241 ccaatagttt agtggcggaa acgatccgga tgaaatttgg tcagaaagtt cctgcctatc
      301 ggcaagagaa ctattggaaa caaacacatg ggttggatat ttcgagagat aatatcacca
      361 attggcatat taaagcagtg caaaacgcgt tagacccttt aggagaacga ttaagagtct
      421 atcttaatca agaagagatt ctacacgggg atgaaacaag ttatcgtgtg attgaaagtg
      481 ccaaaacaga tacctattac tggcagtttt gtacaggaaa agacagtcag catcccatcg
      541 tttattatca ccacgacgaa agtcgtgctg gagatgttcc gaaaactttt ctcaaggagt
      601 ttacagggta tttacactgt gacggctata gcgggtataa tgccgtggaa agtgtacgac
      661 ttgtctattg tttcgcgcat gttcggcgga aatttttcga agcaattcca aaaggaaaga
      721 aaaacacgga tattcccgca gctcaagcag tcaaacaatt ggataaatgg tttgtcctag
      781 aaaagaaatg gaaagacttt tctcctgaga agcgattaag ctgtcggcaa caagaactgc
      841 gtccattatt tattgctttt tatgagtgga tggcaacgat agatcctgtt gcaaaatcca
      901 agttggatgc agccgttcaa tatgcgtgta aactacgaag tggttttgaa cctatttttg
      961 aagatggtcg tttagaactc acaaataatc gtgcggagcg aaatatcaaa gagctggtga
     1021 taggacggaa aaattggttg cattccacaa gtcttgaagg agcacgaact tcaggaatca
     1081 ttctgagtgt atataaaaca gcagaactta acggattgaa tcctgtaaag tatctagagt
     1141 ttctatttga taagatacca aatcttcccg tactttcagc agaaacttta gatcaactgt
     1201 tgccttggaa caaggatgta caacaacatt tttctcgtaa ctaaaaacgc caaacattcc
     1261 cgattctatt ctataggtcg ggttatttga cgta
//
LOCUS       DAFBVQ010000172         1290 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.179, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000172 DAFBVQ010000000
VERSION     DAFBVQ010000172.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.179"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>1290
                     /locus_tag="LLC22_002908"
     rRNA            <1..>1290
                     /locus_tag="LLC22_002908"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          344 a          286 c          392 g          268 t
ORIGIN      
        1 gaaataatag taccgaagtt cctgatgtca cactgccgag aaaagcttct agtgagaaaa
       61 cagcggcccg taccgcaaac cgacacaggt agtcgaggag agaatcctaa ggtgagcgag
      121 agaactctcg ttaaggaact cggcaaaatg accccgtaac ttcgggagaa ggggtgctga
      181 tcatacgatc agccgcagtg aataggccca agcgactgtt tatcaaaaac acaggtctct
      241 gcaaaatcgt aagatgaagt ataggggctg acgcctgccc ggtgctggaa ggttaagagg
      301 agtgcttagc gcaagcgaag gtacgaattg aagccccagt aaacggcggc cgtaactata
      361 acggtcctaa ggtagcgaaa ttccttgtcg ggtaagttcc gacccgcacg aaaggcgtaa
      421 cgatttgggc actgtctcaa cgagagactc ggtgaaattt tagtacctgt gaagatgcag
      481 gttacccgcg acaggacgga aagaccccat ggagctttac tgtagtttga tattgagtgt
      541 ctgtaccgca tgtacaggat aggtaggagc cgtagaaatc ggaacgctag tttcgatgga
      601 ggcgctggtg ggatactacc cctgcgttat ggccactcta acccgcacca ctaatcgtgg
      661 tgggagacag tgtcagatgg gcagtttgac tggggcggtc gcctcctaaa aggtaacgga
      721 ggcgcccaaa ggttccctca gaatggttgg aaatcattcg aagagtgtaa aggcagaagg
      781 gagcttgact gcgagaccaa caagtcgagc agggacgaaa gtcgggctta gtgatccggt
      841 ggttccgcat ggaagggcca tcgctcaacg gataaaagct accctgggga taacaggctt
      901 atctccccca agagtccaca tcgacgggga ggtttggcac ctcgatgtcg gctcgtcgca
      961 tcctggggct gtagtcggtc ccaagggttg ggctgttcgc ccattaaagc ggcacgcgag
     1021 ctgggttcag aacgtcgtga gacagttcgg tccctatccg tcgcgggcgt tggaaatttg
     1081 agaggagctg tccttagtac gagaggaccg ggatggactt accgctggtg taccagttgt
     1141 tctgccaagg gcattgctgg gtagctatgt agggaaggga taaacgctga aagcatctaa
     1201 gtgtgaagcc cacctcaaga tgagatttcc catttcttta agaaagtaag atccctgaga
     1261 gatgatcagg tagataggtc aggagtggaa
//
LOCUS       DAFBVQ010000173         1288 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.180, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000173 DAFBVQ010000000
VERSION     DAFBVQ010000173.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1288)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1288)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1288
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.180"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            282..521
                     /locus_tag="LLC22_002909"
     CDS             282..521
                     /locus_tag="LLC22_002909"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002343604.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436094.1"
                     /translation="MKRILFISLSNLLLLTACGTSASKNIPSDTQISNSIDSTISTNE
                     KNSPVETSDIKVSTSAKNRVKKLSARLLYFKQTLN"
     gene            complement(883..1143)
                     /locus_tag="LLC22_002910"
     CDS             complement(883..1143)
                     /locus_tag="LLC22_002910"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002302583.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436095.1"
                     /translation="MNNETIILGKKYICQPIGLKQKVVGEVISKLENCVVICVDEYHD
                     VDRNEILEKCGKVVAKYTHVYELETTEYLYNYSNKYEHTLVS"
BASE COUNT          426 a          235 c          175 g          452 t
ORIGIN      
        1 tatcctccta gcaactattt aaatacccaa aaaaattacc tctagataat atcataccta
       61 cgttttcact tataaatttt ttcataaaaa aagcgtttag aggcataatc gttaatacag
      121 atggtaacca atgtatctgg tttgaactgg gatatcaccc tctccatata tgtattacta
      181 agactaatag atactataaa agacttgata gttttgcatt gattttgcct aatactgagc
      241 ataggtgtat gctaaacgat actataagga gtgtgtacat aatgaaaaga attctgttta
      301 tcagtttatc aaatttattg ttacttactg cttgtgggac ttctgcatca aagaacatac
      361 cttcagatac gcaaatttcg aatagtatcg attcaacaat ttctacaaat gagaaaaatt
      421 ctccggtaga aacttccgat ataaaagttt ctacctctgc aaaaaacagg gtaaagaaac
      481 tgtcagcacg tctcctttat ttcaaacaaa ctctgaatta gcttcttcat cttcttcagc
      541 aaataatgat gatagtttcg cgtttactcc taactaaatg caacctttac aaatgcttta
      601 cgataacaag cctgagctaa atgatcctga tatcagtttt gcattttttg aaatgattgg
      661 atcggatgat ctttttaaaa ctactagttt gtctatccga aaataggaca gttctggcag
      721 tataggtttt tatcgagttt ctccaccagg cctcgttaca gagacagatt ctctaggcga
      781 accttttgaa taaatcaaaa atcatgaaca atcactgcca actaaataaa gtgccttcaa
      841 aagcttggtc ttctcgcttt tgaaggcact ttatttaaat ctttatgaaa ctaaagtatg
      901 ttcatatttg ttgctatagt tatatagata ttctgttgtt tccaactcat aaacgtgagt
      961 atattttgcc actacttttc cgcatttttc taatatttca ttgcgatcga cgtcatgata
     1021 ttcgtctacg cagatcacaa cacaattttc taatttactg attacttctc caaccacttt
     1081 ttgtttcaag ccaataggtt ggcaaatata tttttttcct aaaatgatag tttcgttatt
     1141 catatttcat ccatccttaa tgtttttcca ttatttaaaa tgataatacc attaaaatat
     1201 gattatgaaa atcaataaca cttgtgattt tataaaaaaa taaaaaaacc gaaaaacaga
     1261 aatgcccact gtctttccgg ctcttttt
//
LOCUS       DAFBVQ010000174         1246 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.181, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000174 DAFBVQ010000000
VERSION     DAFBVQ010000174.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1246)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1246)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1246
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.181"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            200..742
                     /locus_tag="LLC22_002911"
     CDS             200..742
                     /locus_tag="LLC22_002911"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298088.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436096.1"
                     /translation="MLLKVAIKCYCVKNKGGIIYEKIVPRGACLLLALCLSLSAVGCQ
                     KSNENNKIKEGQSISSEEEGMSINANGKNETFKPSDYTLEAKKEYVYEYLGLKFKLSD
                     KFRNYIADKKIAMLDDQSPIDKELKYAILTFEKMTEEQKNAVIEKMGDGYKNWQNELE
                     RIGTIGIFEKNTSEEKNLKL"
     gene            898..>1246
                     /locus_tag="LLC22_002912"
     CDS             898..>1246
                     /locus_tag="LLC22_002912"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330914.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="TlpA family protein disulfide reductase"
                     /protein_id="HBK5436097.1"
                     /translation="MLSEKTDLENTEAFNKESVKDLRKLPTKDINGKDFTSKDFEKYD
                     LTMVNVFATWCTACVKEIPDLVEVQNEMKSKGVNIVGVVTDPVDDNGENKEAIEKSKL
                     IHEKTKASYPFLMP"
BASE COUNT          514 a          141 c          237 g          354 t
ORIGIN      
        1 attgatgaag cagatcccaa agggctgctt catcaatttt ttcgtaagtg tccgtacact
       61 tactgtgctt gctcatatat taatcgatca tatactaatc gtgtaagaac aactttaagc
      121 ataatactta tattgttata ccatagtttg gaaaaataaa aaattatatt tcatcaacgt
      181 ttcataaaag gtgtgtagaa tgttattgaa agtagctata aaatgctatt gtgtaaaaaa
      241 taaaggagga ataatttatg aaaaaatagt accaagagga gcatgcctat tacttgcatt
      301 atgtttgagc ttaagcgcag ttgggtgtca aaaaagtaat gaaaacaata aaataaaaga
      361 aggacaatcc ataagttctg aagaggaagg catgtcaatt aatgcaaatg gcaaaaatga
      421 aacttttaag ccatcagatt atacattgga ggcaaagaaa gaatatgttt atgaatattt
      481 agggcttaaa tttaaactct cagacaaatt tagaaattat atagctgata aaaagatagc
      541 gatgttagat gatcaaagtc ctatagataa agaactaaag tatgctattt tgacatttga
      601 gaaaatgaca gaagaacaaa agaatgcagt tatagaaaag atgggcgatg gatataaaaa
      661 ttggcaaaat gagcttgaaa gaattgggac tattggtata tttgaaaaaa atacatcaga
      721 agaaaaaaat ctaaaattat aaaatgtgat actcatacta aaataggagt ttcaagtgat
      781 ggaaaatacg attgctattt aagcacaaat agcggagctg aaagtaatct tcttgatgaa
      841 ttaaaaagaa ctgagattca aattatagat aaaaaagaac gtcctaaaaa tggttttgtg
      901 ctatcagaaa aaactgattt agaaaataca gaagcattta acaaagaatc ggttaaagat
      961 ttacgtaaac taccaacaaa ggacataaat ggcaaggatt ttacaagtaa agattttgag
     1021 aagtatgatc ttactatggt aaatgtattt gcaacttggt gtacagcttg tgtaaaggaa
     1081 attcctgatt tggttgaggt tcagaatgaa atgaaaagca agggtgtaaa tatcgttgga
     1141 gttgttacag atcctgttga tgataacggt gaaaacaagg aagcaattga aaagtcaaag
     1201 ttaatacatg aaaagacaaa ggcttcatat cctttcttaa tgccag
//
LOCUS       DAFBVQ010000175         1212 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.182, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000175 DAFBVQ010000000
VERSION     DAFBVQ010000175.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1212)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1212)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1212
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.182"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            11..1189
                     /locus_tag="LLC22_002913"
                     /pseudo
     CDS             11..1189
                     /locus_tag="LLC22_002913"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002324322.1"
                     /note="internal stop; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEfm2 family transposase"
BASE COUNT          404 a          242 c          237 g          329 t
ORIGIN      
        1 ggacttccat atgaacgatt ttactacaga aattctaaag actctagcga acaaaggcga
       61 tttgaatgaa ttattccgtg tccatttgga aaaagctgtc aatacgcttc tcaaaacgga
      121 gttaacggct ttcctcgatt acgaaaagta cgatcgcatt ggttttaaca cggggaattc
      181 tcgtaacggc tcctatgacc gtacggtcaa gaccgagtac ggggaacttc atctccagat
      241 tccgcgcgac cgcaacggcg agttcaagca acagactgtt cctgcttata gacggacgaa
      301 tgatacctta gaggagaccg tcattcacct cttccgaaaa ggtattacca tgtcggaaat
      361 cgcagacttg attgagaaaa tgtatgggca tcactacacg ccccaaacca tgtccaacat
      421 gactaaagtg ctgactgaag aagtaaatgc atttaaagtt agaactctaa atgataagta
      481 tgtcgctatt ttcatggatg ctacttatat tcctttaaaa cggcaaaccg tctccaaaga
      541 agcaatctat attgccattg gtatacgaga agacggcact aaagaagtac taagttatgc
      601 gattgctccg actgaatcga cctacgtttg gaatgagttg ttacaggaca tttactccag
      661 aggggttcat gatgtcttac tgtttattac cgatggctta aaaggcatga aagatacgat
      721 tcaccagatt tatcctaaag ctaaatacca acattgctgt gttcacgttt cccgtaatat
      781 tgctcataaa gtacgtgtca aagatcgaaa agaaatctgt gatgatttta aggctgttta
      841 tcaagctagc tcaaaggaag aggcaaatac ctttttaggg agtatgattg agaagtagca
      901 aaaaacttat cctaaagtga cgcagtcact gataaaaaat caagatttat tgacttttta
      961 tgagtttccg cctggtatcc gccgaagcat ttactcaact aatttaatcg aatctttcaa
     1021 gaaacaaatc aagaaataca gccgcagaaa agagcagttt caaaatgaag aatcactaga
     1081 gcgtttccta gtatccatct ttgatacata caatcaaaaa ttcttaaata gaagccataa
     1141 aggcttccaa caagtgacgg atacattagc ttcaatgttt actgagtaac ccattatttt
     1201 gcagaaggac ga
//
LOCUS       DAFBVQ010000176         1193 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.183, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000176 DAFBVQ010000000
VERSION     DAFBVQ010000176.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1193)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1193)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1193
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.183"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..1076
                     /locus_tag="LLC22_002914"
     CDS             <1..1076
                     /locus_tag="LLC22_002914"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBK5436098.1"
                     /translation="VIGMESTSMYSFHPSMFFHEDEKLKKLNTLVTIENPFRVKQFSR
                     MFDENKTDRNDALRIADFLRIQRFTTSPIKEEKYMALQRLTRTRYQLIKQLIRTKQHF
                     LENLTYKCNTLAREMRDESTSLFSATLISLMTEDFTLDELAELPLEAFCDLLQEKGKG
                     RFKQPEKIAKAIQRAITMSYRLGALAQESINVVLSVLVREIRALEKNIKELDKAIEQV
                     IVVIPEYQCLTSIPGVGKVYAAGLIAEIGQIERFEDQTKLAKYAGLSWKVNQSGNYQS
                     QNTPLTKQGNRYFRYYLVEAANSVKNYLPEYKAFYQSKYKEVPKHQHKRALVLTARKF
                     TRLVDTLLRKHQLYTPPRSVIEK"
BASE COUNT          418 a          234 c          210 g          331 t
ORIGIN      
        1 ttgtgattgg catggagtca acgtccatgt acagcttcca tccttccatg ttttttcatg
       61 aagatgagaa actaaagaag ctcaacacac ttgtaacgat tgaaaatcct tttcgggtga
      121 aacaatttag tcgcatgttt gatgagaata aaactgatcg aaacgatgca ttaagaatcg
      181 ctgatttctt gcgtattcaa cgattcacaa cttcccctat caaagaagag aaatacatgg
      241 ccttacagcg tttaacacgt actcgctatc aacttattaa gcaattgatt cgtacaaagc
      301 aacattttct tgaaaatcta acgtacaaat gtaatacgct tgctcgagaa atgcgagacg
      361 aatcgacgag tctttttagt gcaaccctca tttcactcat gacggaagat ttcacattgg
      421 atgaacttgc tgagcttcct ttagaagctt tctgtgattt acttcaagaa aaaggaaaag
      481 gccgtttcaa gcaaccagaa aaaatcgcta aagcaattca acgtgcaatt accatgagtt
      541 accgcctagg tgctcttgca caagaatcaa ttaatgttgt tttaagtgtt ctcgtacgag
      601 aaatacgagc acttgaaaaa aatatcaaag aattagataa agccatcgaa caagtaattg
      661 ttgtcattcc agaatatcaa tgcttaacca gtattccagg cgttggtaaa gtctatgctg
      721 ccggtttaat cgctgaaatt ggtcaaatcg aaagatttga agatcagaca aaattggcaa
      781 aatacgctgg attaagttgg aaagtgaacc aatctggaaa ctatcagtcg caaaatacac
      841 ctctgacaaa acaaggaaat cgatatttta gatactactt agttgaagct gccaactctg
      901 taaaaaatta tcttcctgaa tacaaagctt tttatcaaag taaatataag gaggttccaa
      961 agcatcaaca caaacgtgca ctcgtcctaa ccgcaagaaa atttacgcgt ctggtggata
     1021 cgctactacg taaacaccaa ctctatacgc caccaaggag tgtgatagag aaataacaat
     1081 ccgttattga cgcaaatcct tgaatcaacc cgaaaaaaat ttgattttga tcgggtctag
     1141 tttcgtgcgc ttcaaaacat attactcaat aaagaaaatc ttaaatttca tct
//
LOCUS       DAFBVQ010000177         1188 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.184, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000177 DAFBVQ010000000
VERSION     DAFBVQ010000177.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1188)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1188)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1188
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.184"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            141..398
                     /locus_tag="LLC22_002915"
     CDS             141..398
                     /locus_tag="LLC22_002915"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339958.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436099.1"
                     /translation="MSNLENKEEKVVNKIVSVVNKLDKELDELDTLSENPEKKHNLKK
                     WLVERKAIHEIKKVLHEADKYEKYDEKELDKEFKEINDLLL"
     gene            complement(630..1061)
                     /locus_tag="LLC22_002916"
     CDS             complement(630..1061)
                     /locus_tag="LLC22_002916"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002363335.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF4231 domain-containing protein"
                     /protein_id="HBK5436100.1"
                     /translation="MIGEKMMDQKAFIESIDSTIDRLKKEIRFYNRVIGIGNIIKIVL
                     SASIPILIDQASEHRSLLLIVSIASAIITIIQSGMSAFNYQDKVQTSTELLMKIEKEK
                     LLYITKTSPYNKTDEENFHLIVTTLQTELNDIISDFNQVNN"
BASE COUNT          453 a          151 c          148 g          436 t
ORIGIN      
        1 ttctgtccac gttcatttta ctccaaagtt ttcctcattt caaaagaaaa tcacagaata
       61 cacgaagaag cgtttctatt tgtataaact atatcaaagt tctatactta aattatcaaa
      121 taaaaaggac gtgaagataa atgtcaaatt tagaaaacaa agaagaaaaa gttgtaaaca
      181 aaattgtttc tgttgtcaat aaactggata aagagttaga cgaacttgat acgttatctg
      241 aaaatccaga aaaaaaacat aacctaaaaa aatggttagt tgaacgaaag gctattcatg
      301 aaattaaaaa agttcttcat gaagctgata aatatgaaaa atatgatgaa aaagaacttg
      361 ataaagaatt taaagaaatc aatgacttat tactataatt gatttatacg actcattttt
      421 gagtcgtcag actgcaaaca acactctaaa tttaggagtt tgtctacagt ctgaataaat
      481 tttaaattta ttgtccataa tgttattatg aatttatagc attaagaaaa gagataagac
      541 tttacatttt tttaggaatg taaagtctta tctcttttct taattgtaca attagtatta
      601 tctgcactac tttctaatta aataaatttt tagttattaa cttgattaaa atcagagata
      661 atatcattta attcagtttg aagggttgta acgattaaat ggaaattttc ttcatctgtt
      721 ttattatatg gggatgtttt cgttatatat aacaactttt ctttttcaat tttcattaat
      781 aactctgtcg aagtctgtac tttatcttga taattaaatg cagacatacc actttgtata
      841 attgtaatta ttgctgaagc aattgaaaca atcaatagta aagacctgtg ttcggaagcc
      901 tgatcaatta atattgggat actagctgat aagactattt ttataatatt tccgatacca
      961 attactctat tataaaatcg aatttctttt tttaatctat cgattgtaga atcaatagat
     1021 tcgataaacg ctttttgatc catcattttc tctccaatca ttttattaaa atcattaaca
     1081 aaaatattat aataggattt aagtaagttc taactaatca catataaaaa taaaaaaaca
     1141 tttgtatttt atcaaagttt tattatactt gtcaatttgt gtacatcc
//
LOCUS       DAFBVQ010000178         1091 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.185, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000178 DAFBVQ010000000
VERSION     DAFBVQ010000178.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1091)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1091)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1091
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.185"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            6..980
                     /gene="bsh"
                     /locus_tag="LLC22_002917"
     CDS             6..980
                     /gene="bsh"
                     /locus_tag="LLC22_002917"
                     /EC_number="3.5.1.24"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342103.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="choloylglycine hydrolase"
                     /protein_id="HBK5436101.1"
                     /translation="MCTSITYVTSDHYFGRNFDYEISYNEVVTVTPRNYKLNFRKVND
                     LDTHYAMIGIAAGIADYPLYYDATNEKGLSMAGLNFSGYADYKEIQEGKDNVSPFEFI
                     PWILGQCSTVGETKKLLKNINLANINYSDELPLSPLHWLLADKEKSIVIESMKDGLHI
                     YDNPVGVLTNNPSFDYQLFNLNNYRVLSSETPKNNFSNQISLNAYSRGMGGIGLPGDL
                     SSVSRFVKATFTKLNSVSGDSESESISQFFHILGSVEQQKGLCDVGDGKYEYTIYSSC
                     CNVDKGIYYYRTYEDSQITAIDMNKEDLDSHKLISYPIIEKQQIKYIN"
BASE COUNT          384 a          135 c          187 g          385 t
ORIGIN      
        1 aaactatgtg tacgtctatt acttatgtaa caagtgatca ttattttgga aggaattttg
       61 attatgaaat atcttacaat gaagtagtta ctgttactcc aagaaattat aagttgaatt
      121 ttcgaaaggt aaatgatttg gatactcatt atgcaatgat tggtattgcc gctggtatag
      181 ctgactaccc tctttattac gatgcgacaa atgaaaaagg attgagtatg gctgggctaa
      241 atttttctgg gtatgctgat tataaagaaa tacaagaagg gaaagacaat gtatctcctt
      301 ttgaatttat tccttggatt ttaggacaat gctcaacagt aggagaaact aaaaaattgt
      361 taaaaaatat caatttagca aatataaatt atagtgatga acttccttta tcccctttac
      421 attggctatt agctgataaa gaaaaatcaa ttgtcattga aagtatgaaa gatggacttc
      481 atatatatga taaccctgtg ggcgttctta ccaataatcc ttcatttgac tatcaattat
      541 ttaatttaaa caattatcgt gtcttatcga gtgaaactcc taaaaataat ttttcaaatc
      601 aaataagttt gaatgcctat agccgcggta tgggagggat aggcttgcct ggagatttat
      661 cctcagtatc tcgttttgtt aaagcgactt ttacgaagct gaattctgta tctggagatt
      721 cagagtcaga aagtattagt caatttttcc atatcttagg ttcagtagaa caacaaaaag
      781 gtttgtgtga tgttggtgat ggaaaatatg aatatacaat ttattcttct tgttgcaatg
      841 ttgacaaagg aatctattat tatcgaacat atgaagacag tcaaattact gcaattgata
      901 tgaataaaga agacttagat agtcataagt taattagtta tccaattata gaaaaacaac
      961 aaattaaata tataaattag ttaatgtgtt gtgattgatt atttaatata gatataatac
     1021 aaaaaggcaa agatattttc aaaacatttt ttcttgatgt gatatccttg tcttttttgt
     1081 aatgttttta a
//
LOCUS       DAFBVQ010000179         1058 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.186, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000179 DAFBVQ010000000
VERSION     DAFBVQ010000179.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1058)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1058)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1058
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.186"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(36..992)
                     /locus_tag="LLC22_002918"
     CDS             complement(36..992)
                     /locus_tag="LLC22_002918"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326835.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436102.1"
                     /translation="MELYTLPIIIKTEKMLKDLKQYYPLSAYEKKKLFHFLAINLLAE
                     QADSLDIASNQSLFFSDIGFYHLKGVLGEKSVIFINKTLSWLYLHDKLDQKYLRKNED
                     ETIEWLNERFIESFENQFNLLREETSQLIRRELTKIHFKLLHYTINKADEFPLDVSFF
                     RENYPAFYCYLIEYINDLTSKRKELLQDKFFLFFSYLLLLINHIPIQLISEPVKIIID
                     FSYGAAYNQFIKKNLSLYINLNTEVIEAGKPEFPDVIITNRNNLYEESASQVVVWLDP
                     PRAVDWGNLTKILLTIQEEKYKDSKIDKQIDDFPEEIIDRIE"
BASE COUNT          344 a          176 c          160 g          378 t
ORIGIN      
        1 tagaaaaagc agtcggactt tctaaaagaa gttcactatt cgatcctgtc gatgatttct
       61 tcaggaaaat cgtctatttg cttgtcaatt ttgctgtctt tgtatttctc ttcttggata
      121 gtcaacaaaa tctttgtaag attcccccag tctactgctc ttggcggatc gagccaaacc
      181 actacttgag atgcactttc ttcatataga ttattcctat tcgtgattat aacatccggg
      241 aactcaggct ttcctgcctc tatcacttcc gtgttcagat taatgtacaa gcttaaattt
      301 ttcttgataa attgattata ggcagcacca taagaaaaat cgatgatgat ctttactggt
      361 tcagaaatca gttgaatggg tatgtgattg atcaataata ataaataact gaaaaaaaga
      421 aaaaatttat cttgaagcaa ctctttgcgt tttgacgtta gatcatttat atactctatc
      481 aaatagcaat aaaatgctgg atagttttct ctaaaaaaag aaacatcaag tggaaattca
      541 tcagctttat taatagtgta atgcaaaagt ttaaaatgta ttttggttaa ctctcttcgg
      601 atcaattggc tcgtctcttc tcgcaacaga ttaaactgat tttcaaaact ttcaatgaat
      661 cgttcattca accattcgat tgtttcatct tcattttttc tcaagtattt ttgatccaat
      721 ttatcatgaa gataaagcca agagagtgtc ttattgataa aaataacgga tttttctcct
      781 aatactcctt ttaagtggta aaatcctata tccgaaaaaa atagcgactg attgctagca
      841 atatctaaag aatcagcttg ttcagccaac aggttgattg ctaaaaagtg gaataatttc
      901 tttttttcat aagcagacag aggataatac tgttttaaat cttttaacat tttttctgtt
      961 tttataatta taggtagcgt atacaattcc acaaaactta tctctgttga gttaaaaaga
     1021 ttatataaaa aaagccgaat gtttttagga ttccctgt
//
LOCUS       DAFBVQ010000180         1005 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.187, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000180 DAFBVQ010000000
VERSION     DAFBVQ010000180.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1005)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1005)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1005
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.187"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(128..775)
                     /locus_tag="LLC22_002919"
     CDS             complement(128..775)
                     /locus_tag="LLC22_002919"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010728800.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="elongation factor G-binding protein"
                     /protein_id="HBK5436103.1"
                     /translation="MEQTIKPYQYFFIIREVEQLLNAYSSVNDPKTVQTVQALAAEKI
                     RDILDHELPEIDTFLTTVLDVKLTKAQAERALEELKQIVQPFMQPSKPQIEKLFRKVK
                     KLKQPAWNEIDLQEHTYIGWNDPGTQKKFMVYYEDEKLKGISGTLSPTINKGICAICQ
                     KTSNVSLFLSTTKAGSDGTYTKKGNYICHDSDQCNQQLTKLAPFYEFAERVKKER"
BASE COUNT          280 a          192 c          167 g          366 t
ORIGIN      
        1 agaaaggggc tgtccccaga ctttagtagg cgtcattagc tatctttcgt tagcatttaa
       61 aggcgaacac catcacctat tcacttccat taaaagatag catatttttc tgtaaaaaac
      121 aataaaatta tcgttctttc tttacacgtt cagcaaattc atagaaagga gccaatttcg
      181 ttaactgttg attacattgg tcactatcat gacaaatata attccccttt ttcgtatacg
      241 tgccatcaga acctgctttc gttgtagaaa gaaaaagcga aacattcgat gttttctgac
      301 agattgcaca gattccctta tttatcgttg gtgataaagt accgctaatc ccttttaatt
      361 tttcatcttc gtaatagacc atgaattttt tctgcgtacc tggatcattc cagccgatgt
      421 acgtatgttc ttgcaagtcg atttcattcc aagctggttg tttgagtttt ttcacttttc
      481 ggaataattt ctcgatttgt ggtttgctag gctgcataaa cggctgaacg atttgcttca
      541 gctcctccaa tgctctttct gcttgcgctt ttgtcagttt tacgtctaaa actgtcgtta
      601 aaaatgtatc gatttctggc agttcgtgat ctaatatgtc tcgaatcttt tcagctgcta
      661 gtgcctgaac tgtttgtacc gtttttggat cattgacaga tgagtacgca tttaataact
      721 gttctacttc tcttattata aaaaaatatt ggtatggttt tattgtttgt tccatgattt
      781 taaagtcctt tcttctaacc aaagtgcata ctttgtagaa aaaagtgatc ttctgcaaag
      841 tatgtgttac ctgaagatcc tggactcttt taaataagat acgttttgca tcttatcatc
      901 acccccttta atgcttatta ttctatgtac atgattcatt cgataaataa aagtaaaccg
      961 tatcttgaac agatagtcaa ctgcaaacag aaaaaaggac tgtga
//
LOCUS       DAFBVQ010000181         1002 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.188, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000181 DAFBVQ010000000
VERSION     DAFBVQ010000181.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1002)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1002)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1002
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.188"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            52..307
                     /locus_tag="LLC22_002920"
                     /pseudo
     CDS             52..307
                     /locus_tag="LLC22_002920"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010752209.1"
                     /note="frameshifted; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="tyrosine-type recombinase/integrase"
     gene            371..1002
                     /locus_tag="LLC22_002921"
                     /pseudo
     CDS             371..1002
                     /locus_tag="LLC22_002921"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3 family transposase"
BASE COUNT          344 a          181 c          183 g          294 t
ORIGIN      
        1 tttcaaagtt agtagagaaa atgtagttat atatttaaat ttttaccaga aagaaatgaa
       61 caccttcaat tatctaaatc tcgaaaatgg ttagatgtaa tcatcaggaa aaacaatctt
      121 aaacgaatta ctattcatgg tcttagacac acacatgcta gcttgctttt agcaagctag
      181 tgcaaatatt aaagatgtgc aagagcgttt aggccactct tctattcaaa tcattatgga
      241 tctatatatt catattacag acaaaagaaa agaagaaacc gtagcgcaat tcgcaaaaaa
      301 tataggctct ataatttatg ggactgatga atcaaaattg attcttcagt cccattgtta
      361 ttttaggtat atgattcgta cattgaaaga gttgaaaaac tatcttccga agccgtcaaa
      421 aaggaccctg ccaaaagtat tgatggtgga tgaatttcgt tcgcacgctt caattgtgga
      481 taaaatgagc tttatttgtg cggatggcga gactggaaaa ctcattgata ttttgcctac
      541 acgaaaattg tctcgattaa cacactattt tagtcgctgt gcaaatcctg aagcggtgga
      601 atatttagtg acagatatga acgccgccta cttccaactg acaaaacgtg tcttaccaaa
      661 tgcgaaagtc gtcattgatt gttttcatat catcaaacat ttgaatcagg cgttcaatga
      721 ttttcgtgta caagaaatga aaagattaca ccagttaggg caacgacggg aagccgagaa
      781 agtgaaaaag aactggcgct ttcttctaaa aaaccgtcaa aaaatcaatc actatgatta
      841 caaaacatgg cgcagttttc gtgcacctaa atacccgcta ctcactgaag caatgatgat
      901 tgatcgattg ctggcatttt caacgccttt aaaggacgcc tatacttttt tccatgagct
      961 gaccgaagcc tttagagaca aggaatcaga cttatttttt ac
//
LOCUS       DAFBVQ010000182          984 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.189, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000182 DAFBVQ010000000
VERSION     DAFBVQ010000182.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 984)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 984)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..984
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.189"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            94..969
                     /locus_tag="LLC22_002922"
     CDS             94..969
                     /locus_tag="LLC22_002922"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002305366.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramoyl-L-alanine amidase"
                     /protein_id="HBK5436104.1"
                     /translation="MHETGIDAPARNVAANMKNNYNGSNSYTTDVIGDGGIVYRVGEQ
                     GYVSWGAGNANPYAPVQIELQRTYDKALFEKNYRAYIEYTRDSAKKYGIPLTLDQGTS
                     LFTKGIISHLWVTNYVWGNHTDPYGYLSQMGVSKEKLAYDLAHGFTDENPTTSDDKPV
                     IDPTRAGAANPTLTDGTNHAHIDQFGEIENANLHVAGWHIANYKYEYIFIMDYNTGKE
                     LARVRADGIYRPDVNQAYNTSGNVGYHVSFNMRNFPNKKVYVMMRATNDPEGNTKGGA
                     QDFHDKRWYLNIPQR"
BASE COUNT          343 a          167 c          199 g          275 t
ORIGIN      
        1 cccattaata cgtttgctta tactattaat gacgagtata atttagcgcc gaatcaagga
       61 gactccagat tagcaattcc taacaaaatt attttgcacg aaactggaat agatgcacca
      121 gcaagaaacg tagccgccaa catgaaaaat aattataacg gaagcaattc ttatactaca
      181 gatgttattg gtgacggtgg gattgtttac cgtgtgggtg agcaaggata tgtttcgtgg
      241 ggagctggta acgctaatcc ttatgcgcct gtacagattg aattacagcg cacatatgat
      301 aaagcattgt ttgaaaaaaa ctatcgagct tatattgaat atacaagaga tagtgcaaaa
      361 aaatatggaa ttccattgac tcttgatcaa ggaacttctt tatttacaaa aggaatcatt
      421 tctcatttgt gggtgacaaa ttatgtttgg gggaaccaca cagatccata tggttactta
      481 tcgcaaatgg gagttagcaa agaaaagctt gcttatgatt tagctcatgg atttaccgat
      541 gaaaatccaa ctacttcaga tgataaacca gtcattgatc caactagagc aggtgcagca
      601 aatcctacgc tgacagatgg aacaaatcac gcccacattg atcagtttgg agaaatcgaa
      661 aacgcaaact tgcatgtggc tggatggcac attgctaatt ataaatacga gtatattttc
      721 attatggatt acaatactgg aaaagaatta gctcgagtaa gagctgatgg aatttataga
      781 ccagatgtaa atcaagctta taatacttct ggaaacgttg gttatcatgt atctttcaat
      841 atgcgtaatt ttcctaataa gaaagtctat gtaatgatgc gtgcaacgaa tgatccagaa
      901 gggaacacta aaggcggagc acaagatttt catgataaac gctggtattt aaatattccg
      961 caacgataaa aaaagcccct cgat
//
LOCUS       DAFBVQ010000183          981 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.190, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000183 DAFBVQ010000000
VERSION     DAFBVQ010000183.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 981)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 981)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..981
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.190"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>981
                     /locus_tag="LLC22_002923"
     rRNA            <1..>981
                     /locus_tag="LLC22_002923"
                     /product="23S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF02541"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF02541"
BASE COUNT          304 a          194 c          284 g          199 t
ORIGIN      
        1 attgtgtgaa tacatagcac attcgaggta gacgcagaga actgaaacat ctaagtacct
       61 gcaggaagag aaagaaaatt cgattccctg agtagcggcg agcgaaacgg gaaaagccca
      121 aaccagcaag cttgcttgtt ggggttgtag gactccaata tggtagttct ttcagatagt
      181 cgaatgactt ggaaaagtca gtcaaagagg gtaaaaaccc cgtagacgaa atgtggaaga
      241 cacctaggag gatcctgagt acggcggaac acgagaaatt ccgtcggaat ccgggaggac
      301 catctcccaa ggctaaatac tccctagtga ccgatagtga accagtaccg tgagggaaag
      361 gtgaaaagca ccccggaagg ggagtgaaat agaacctgaa accgtgtgcc tacaacaagt
      421 caaagcccgt taatgggtga tggcgtgcct tttgtagaat gaaccggcga gttacgattg
      481 catgcgaggt taagttgaag agacggagcc gcagcgaaag cgagtctgaa tagggcgttt
      541 gagtatgtag tcgtagaccc gaaaccatgt gatctaccca tgtccaggtt gaaggtgcgg
      601 taaaacgcac tggaggaccg aacccacgta cgttgaaaag tgcggggatg aggtgtgggt
      661 agcggagaaa ttccaaacga acttggagat agctggttct ctccgaaata gctttagggc
      721 tagcctcgga attgagaatg atggaggtag agcactgttt ggactagggg cccatctcgg
      781 gttaccgaat tcagataaac tccgaatgcc attcattcat atccgggagt cagactgtga
      841 gtgataagat ccatagtcga aagggaaaca gcccagacca ccagctaagg tcccaaaata
      901 tatgttaagt ggaaaaggat gtggggttgc acagacaact aggatgttgg cttagaagca
      961 gccaccattt aaagagtgcg t
//
LOCUS       DAFBVQ010000184          891 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.191, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000184 DAFBVQ010000000
VERSION     DAFBVQ010000184.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 891)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 891)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..891
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.191"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>891
                     /locus_tag="LLC22_002924"
     CDS             <1..>891
                     /locus_tag="LLC22_002924"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002293527.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type IA DNA topoisomerase"
                     /protein_id="HBK5436105.1"
                     /translation="PRLFSLSSLQSKMNQLMKASAKDTLEAMQGLYEGKYLSYPRTDT
                     PYITEGEYAYLLDHLDEYKHFLKAEAIPTPIHTPNSRYVNNKKVQEHYAIIPTKTVMT
                     AAAFEQLSPLQQAIYEQVLKTTVAMFAEKYTYEETTILTQVQQLQLKTVGKVPVDLGW
                     KKLFGKESDRKEKEEEPLLPKVTKGEAVTVDLQVLEKETKPPQPYTEGTLITAMKTAG
                     KTVDSEEAQSILKEVEGIGTEATRANIIETLKQKEYIKVEKNKLVVTNKGILLCQAVE
                     KEPLLTSAEMTAKWESYLLKI"
BASE COUNT          335 a          169 c          195 g          192 t
ORIGIN      
        1 ccacgtcttt tttctctatc cagccttcaa tctaaaatga atcagctcat gaaagctagt
       61 gccaaagata ctttggaagc catgcaaggg ttgtatgaag ggaaatatct aagctaccca
      121 cgaacagata ccccttatat tacagaaggg gagtatgcgt atctgttgga tcacttagac
      181 gaatacaaac actttttaaa ggccgaagcc attcctactc ctattcatac accgaatagt
      241 cgatatgtga ataataagaa agtccaggaa cattacgcga tcattcctac aaagacggtc
      301 atgacggcag cggcttttga acaattaagt ccactgcagc aggctattta tgaacaagtg
      361 ttaaaaacaa cggtggccat gtttgcggaa aagtatacct atgaagaaac aacgatcttg
      421 acgcaagttc agcagcttca gctaaagaca gtcggaaaag taccagtaga tctaggttgg
      481 aaaaagctgt ttggcaaaga gagcgacaga aaagaaaagg aagaagaacc gctacttcct
      541 aaagtgacaa aaggagaagc ggtgacggta gatctacaag tccttgaaaa agaaacgaag
      601 ccaccacaac cttataccga aggtacgttg atcacagcga tgaaaacagc tggaaaaacc
      661 gtggatagcg aagaagcaca atccatattg aaagaagtag aaggaatcgg tacagaagca
      721 acacgagcaa atattattga aactttgaaa caaaaggaat atatcaaggt agaaaaaaat
      781 aagcttgtgg tgacaaataa agggatttta ctttgccaag ccgtggaaaa agagccgctg
      841 ctaacaagtg ccgaaatgac cgccaaatgg gaaagttact tattaaagat t
//
LOCUS       DAFBVQ010000185          884 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.192, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000185 DAFBVQ010000000
VERSION     DAFBVQ010000185.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 884)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 884)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..884
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.192"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
BASE COUNT          311 a          144 c          139 g          290 t
ORIGIN      
        1 aaatgttgat cgtcagcaag gagctaaaaa atacgaatat atttcttttg tagtaaaatc
       61 ggactggttt gcatatcatt ttcttcgtaa atatcaaaat catgttaact actatcaatt
      121 actaataaaa actaccactt taagcgttaa gaactgttaa gtttagttaa gtgaggatag
      181 ttcacaaaat ccattgttaa acttcacgaa agtggtaaaa ctcaaaatgc tttatatagg
      241 attacagcat cgctctttct tcgattgcgc gttgggtaaa aaatattatg aagtaaaaat
      301 tgacgatgac acgttcctta cggctcatca gatgaaacag ctacaaaaac gaaatgatca
      361 actcgaagaa aatttaattc taaaaaagcg attgccatat tcacgcctcg ctcgacgaac
      421 tattaaaggt caagatttac ctgaagatca tcctttttag gaaattgaag ctttttatgt
      481 tgcacaatgc atttataata ctacaatgat gttttcacca gatattcttc tagggtgcgg
      541 tgtaatgaaa cagatacact tgcaaaagaa aattcaccgc gaatttacta aaattatgaa
      601 taattatgtt aatcttccga aatttttttc caaaattaag ggatcaagct ggtgttatag
      661 attgtttaag gttggcaaaa aaataacttc tttttaaaca attatagaaa accgatactc
      721 tgttaagttg gttgacacgg tgtcgatttt tatgactttc ttattctgaa acttcactaa
      781 cggacagtac ctaaaaagtc tatagtatgg acgtttacga gtactatttt atcaaaaatg
      841 ctgctcattt caacttatat gttttagtga actaccccca ctta
//
LOCUS       DAFBVQ010000186          791 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.193, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000186 DAFBVQ010000000
VERSION     DAFBVQ010000186.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 791)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 791)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..791
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.193"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..782
                     /locus_tag="LLC22_002925"
     CDS             <1..782
                     /locus_tag="LLC22_002925"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002330615.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5436106.1"
                     /translation="DMLDYYYFEKNLSYNYVIHLKTFTGMIFKFANRRYGLKYNPVNG
                     VSLARKPKTNEEIKKEKDGYLSKEEVQMIASKQKSSHQQSRYSLITKFLFLTGLRYGE
                     LISLTESDYDGNKITVSGTYDYELKIKTTTKNTGSYRTIELSSNAKEIIDQLIEENKL
                     IKNNKDKYIFISKNGNPISIQAYNQSLRAVSKELNIDKKVSSHMLRHSHISLLTELGI
                     PLKAIMDRVGHEDSKTTLKIYTHTTKNMQNQLVEKLGKIEI"
BASE COUNT          340 a          107 c          102 g          242 t
ORIGIN      
        1 aagatatgct agattactac tattttgaaa aaaatttatc atataattat gtaatacatt
       61 taaaaacttt tacaggaatg atttttaaat tcgccaaccg tcgatatgga ttaaaatata
      121 atcccgtaaa tggggtttct ttagcaagaa aacctaagac aaacgaagaa ataaaaaaag
      181 aaaaagatgg ttatttatca aaagaagaag ttcaaatgat tgctagtaaa caaaaaagtt
      241 cacatcaaca gtcacgttat tctttaatta ctaaattttt gtttttaact ggactacgtt
      301 atggtgaatt gatatctttg actgaatctg attatgatgg taataaaatt acggtttctg
      361 gtacttatga ttacgagtta aaaattaaaa caacaactaa aaatacaggt tcttatagaa
      421 ccattgaatt atcaagtaat gctaaagaaa tcatagatca attaattgaa gaaaacaaat
      481 taattaagaa taataaagat aaatacattt tcatctctaa aaatggtaac ccgatatcta
      541 ttcaagcata taatcaatct ttaagagcag tatccaaaga attaaacata gataaaaaag
      601 tttcttctca catgttaagg cattcccaca tttctctact tacagaatta ggaatcccat
      661 taaaagccat tatggatcgt gtaggacatg aagattcaaa aacaacatta aagatttata
      721 ctcatacaac taaaaatatg caaaatcaac tagtagaaaa actaggaaaa atagaaattt
      781 aaattgcccc t
//
LOCUS       DAFBVQ010000187          783 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.194, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000187 DAFBVQ010000000
VERSION     DAFBVQ010000187.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 783)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 783)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..783
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.194"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..672
                     /locus_tag="LLC22_002926"
     CDS             <1..672
                     /locus_tag="LLC22_002926"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5436107.1"
                     /translation="SGKYYISLLCKEEIIELPKTNSTIGIDLGIMDFAILSDGQKIDN
                     NKFTSKMEKKLKREQRKLSRRALLAKNKGTNLFEAKNYQKQKRKVARLHEKVMNQRTD
                     FLNKLSTEMIKNHDIICIEDLNTKGMLRNHKLAKSISDVSWSKFVTKLQYKADWYGRK
                     IIKVDKWFPSSQICSECGHKDGKKSLEIREWTCPVCHTHHDRDINASINILTEGLRLH
                     SMGLA"
BASE COUNT          290 a          120 c          146 g          227 t
ORIGIN      
        1 agcggtaaat actatatttc tttgttgtgt aaagaagaaa ttatcgaatt acctaaaact
       61 aattccacaa ttggtattga cttaggtatt atggactttg cgattctttc tgatggacaa
      121 aaaattgata ataataaatt cacgtccaaa atggaaaaga aactaaagcg tgaacaacgc
      181 aaattgtcta ggcgtgcttt attggctaaa aataaaggta ccaatctatt tgaagctaaa
      241 aattatcaaa aacaaaaacg caaagtagct agattgcatg aaaaagtaat gaatcaacgt
      301 actgattttc tgaataagtt gagtacagaa atgatcaaaa atcacgatat tatctgtatt
      361 gaagacttaa acacaaaagg tatgttgcga aatcataaat tagctaaaag tatttctgat
      421 gtttcttggt caaagtttgt gactaaatta caatacaagg ctgactggta tggacgaaaa
      481 atcatcaaag tagataaatg gtttccgtct agtcagattt gttcagagtg cggacataaa
      541 gatggcaaga aatctcttga aattcgagaa tggacttgtc ctgtttgtca tactcatcat
      601 gatcgtgata tcaatgctag tatcaatatt ctgaccgaag gtctaagact acattctatg
      661 ggattggctt agatccaatc atcaagaacc gtaggaacta cggggatagc ttggtaaata
      721 agagacaccg ctgttagtaa agaaatacgc tatcaagtat gctctattcc caagaagctc
      781 cca
//
LOCUS       DAFBVQ010000188          778 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.195, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000188 DAFBVQ010000000
VERSION     DAFBVQ010000188.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 778)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 778)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..778
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.195"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..603
                     /locus_tag="LLC22_002927"
     CDS             <1..603
                     /locus_tag="LLC22_002927"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997693.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5436108.1"
                     /translation="AIAPTESITIWEEILLDLQERGLKNVLLFITDGLKGMVGAISRF
                     YPKARFQHCCVHVFRNISHKVRVNNRKEVCDDFKMVYQASSKEVALEARGAFAKKWKT
                     SYPKVVESILSNDHLLTFYDFPLAIRKSIYSTNLIESFNKQIKKYSHRKEQFQNEESM
                     ERFLVSSFDTYNQKFLGRSHKGFQQAEGELEQMLSQPMEN"
BASE COUNT          253 a          148 c          149 g          228 t
ORIGIN      
        1 gcgattgcac cgactgaatc catcacgatt tgggaggaaa ttttattaga ccttcaagag
       61 cgcggtttga aaaatgtcct cctgttcatc acggatggct taaaggggat ggtaggagcg
      121 attagtcggt tctatcccaa agctcgtttt caacattgtt gtgtacacgt ttttcgtaat
      181 atcagtcaca aagtgcgtgt caataatcgt aaggaagtct gtgatgattt taaaatggtg
      241 tatcaagcct catctaaaga ggtggcgtta gaagcacgtg gtgcttttgc gaaaaaatgg
      301 aaaaccagct atccaaaagt ggttgaatcg attctttcga acgatcactt gctcactttc
      361 tatgatttcc ccttggccat acgcaagagt atttattcta cgaacttgat tgaatccttt
      421 aataagcaaa tcaagaaata cagccaccgc aaggaacagt tccaaaacga agagtcgatg
      481 gaacgtttct tagtctcgtc ttttgatact tacaaccaaa aattcctagg tcgcagtcat
      541 aaaggtttcc aacaggccga aggcgagctc gaacaaatgc tgagtcaacc gatggagaat
      601 tagaaacaat ctacagtagg gaagaaccat ttacacaaaa ttattgacgc tcccaagcta
      661 aaactcctat taatcgatct actaaaaata aataaaaaaa ttcttttcaa ttttatttat
      721 ggtatgacat aaataaagta aagttattct tctaggttaa tcttattaat actctttc
//
LOCUS       DAFBVQ010000189          775 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.196, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000189 DAFBVQ010000000
VERSION     DAFBVQ010000189.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 775)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 775)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..775
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.196"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(249..728)
                     /locus_tag="LLC22_002928"
     CDS             complement(249..728)
                     /locus_tag="LLC22_002928"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002340462.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436109.1"
                     /translation="MCYFDREQDFFYYGGMGGGSIVPKINLVELDVNNYRELYVFNSL
                     DFEIPMKQMKNIDIHILPSESCQIEYSIEYFYKGKKIKKCDKCFESAVVKFPQFKLNP
                     AASIQFQGHVFDVLAKDNIKKYKKGNIFHIDIQISSNLEDIKKAFKIKTIGTAPNFK"
BASE COUNT          262 a          106 c           87 g          320 t
ORIGIN      
        1 tgacgctccc ttaacaataa atgaagactt ttttattgtt aattgtttat ttttctatta
       61 ttagatatga aaatcgcatt tagataaaat agaaaaatat gaatatattt taaatattaa
      121 gatgagagtc attaacttat gatagtagtc aatttgcttt tcactaatta caaaatatgt
      181 gatataggaa gtttagttat tgttctcata atgccatcct gtttttagat tatctagtaa
      241 tttttttgtt atttaaaatt aggagcagtg ccaattgttt taattttaaa ggcttttttt
      301 atatcttcta aattagaaga tatttgtata tcaatatgga atatattacc ttttttgtat
      361 ttttttatgt tatctttagc taaaacatca aatacatgtc cttgaaattg tatcgaggca
      421 gctggattta gtttaaattg aggaaacttt accacagctg attcaaaaca cttgtcacat
      481 ttttttattt ttttaccttt gtaaaaatat tcgattgaat attctatttg gcacgactca
      541 cttggcagta tatgtatgtc aatatttttc atctgtttca taggtatttc aaaatctaaa
      601 ctattaaaaa catataattc cctgtaatta tttacatcta actctactaa atttatcttt
      661 ggaacaatag atcctccacc cattccacca taataaaaaa aatcttgttc tctatcaaaa
      721 tagcacatat taagctcagt ttgtttatca tcctcaataa ttttataaat caaac
//
LOCUS       DAFBVQ010000190          763 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.197, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000190 DAFBVQ010000000
VERSION     DAFBVQ010000190.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 763)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 763)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..763
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.197"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..>763)
                     /locus_tag="LLC22_002929"
     rRNA            complement(<1..>763)
                     /locus_tag="LLC22_002929"
                     /product="16S ribosomal RNA"
                     /inference="COORDINATES: nucleotide
                     motif:Rfam:12.0:RF00177"
                     /inference="COORDINATES: profile:INFERNAL:1.1.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: cmsearch."
                     /db_xref="RFAM:RF00177"
BASE COUNT          154 a          248 c          166 g          195 t
ORIGIN      
        1 gaattaaacc acatgctcca ccgcttgtgc gggcccccgt caattccttt gagtttcaac
       61 cttgcggtcg tactccccag gcggagtgct taatgcgtta gctgcagcac tgaagggcgg
      121 aaaccctcca acacttagca ctcatcgttt acggcgtgga ctaccagggt atctaatcct
      181 gtttgctccc cacgctttcg agcctcagcg tcagttacag accagagagc cgccttcgcc
      241 actggtgttc ctccatatat ctacgcattt caccgctaca catggaattc cactctcctc
      301 ttctgcactc aagtctccca gtttccaatg accctccccg gttgagccgg gggctttcac
      361 atcagactta agaaaccgcc tgcgctcgct ttacgcccaa taaatccgga caacgcttgc
      421 cacctacgta ttaccgcggc tgctggcacg tagttagccg tggctttctg gttagatacc
      481 gtcaagggat gaacagttac tctcatcctt gttcttctct aacaacagag ttttacgatc
      541 cgaaaacctt cttcactcac gcggcgttgc tcggtcagac tttcgtccat tgccgaagat
      601 tccctactgc tgcctcccgt aggagtttgg gccgtgtctc agtcccaatg tggccgatca
      661 ccctctcagg tcggctatgc atcgtggcct tggtgagccg ttacctcacc aactagctaa
      721 tgcaccgcgg gtccatccat cagcgacacc cgaaagcgcc ttt
//
LOCUS       DAFBVQ010000191          694 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.198, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000191 DAFBVQ010000000
VERSION     DAFBVQ010000191.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 694)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 694)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..694
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.198"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
BASE COUNT          247 a          116 c           84 g          247 t
ORIGIN      
        1 ccaaattact tcatcaaaac attgatataa tttttattat atcagtattt attcttgata
       61 cataaatgag aaaataaata ctttaaatct attgactaca agtagtcatt aagtcttcat
      121 aagatgtaca atatgacatt aaaaaaataa aagcttacga ccatccgtta aatctgacac
      181 taaataatgg actgctttct tttgtattag caggttacgt tgactatgaa tattcaccag
      241 attatttgga gaaacctctt caacacgaga acaatgatat taattttaga tttgtctacg
      301 agtcaaaaag taaaacatgg ttagttgatc aattaagcac gataaacaca agcttccatg
      361 aattacctaa acctgaaaat gaagttgaga tggtcattaa aatcttctaa aaaagaagcg
      421 ttgaagggga aatattcctt tcaacgctct tttttatatg cttagaaaca taaataaatt
      481 gtatactttc tttttagccc ctattacttt tcacgaaaaa tatctttttt tcgacgctag
      541 cgtttctcta cttctaatac tgtacacagt ttttgtatta ttgaaaaatt actcattatt
      601 tagcattaat ccacatcgtt ttatcaatcg accttcatac taaactactt taaagtcatc
      661 ttccttctcg tttttcatta atggaatggc aaca
//
LOCUS       DAFBVQ010000192          685 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.199, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000192 DAFBVQ010000000
VERSION     DAFBVQ010000192.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 685)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 685)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..685
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.199"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            82..>685
                     /locus_tag="LLC22_002930"
     CDS             82..>685
                     /locus_tag="LLC22_002930"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBK5436110.1"
                     /translation="MNDSIKKMLRLIEKDLMITEVSYETFQKKKTLIVDAVFSPAPHT
                     CRNCGSTVVDGNGKVIVVKNGKKETIVRFEQYNHMPLVMRLKKQRYTCKNCRTHWTAQ
                     SYFVQPRHSIANHVRYKIASLLTEKVSLSFIAKNCQVSLTTVIRTLKEFKSYLPKQSK
                     RILPRVLMVDEFRSHASIEDKMSFICADGETGQLIDVLPTR"
BASE COUNT          228 a          119 c          135 g          203 t
ORIGIN      
        1 attttaggta ttaaaaaaca tatcgttctc tagtatgatt aaatcacgac aaaataaaca
       61 actgagagga cgatatgcta tatgaatgat tctatcaaaa aaatgctgcg attaatagag
      121 aaagatttga tgattacaga ggtctcttac gagacctttc agaagaaaaa gacgttgatc
      181 gtcgatgctg ttttctcacc tgctccccat acctgtagaa attgtggttc tactgtggta
      241 gatggaaacg ggaaagtaat tgtagtgaaa aatgggaaga aggaaacgat tgtccgcttt
      301 gaacaataca atcacatgcc tttggttatg cgcttaaaaa agcagcgcta tacctgtaaa
      361 aactgtcgaa cccattggac ggctcaaagt tattttgttc aacccagaca ttcaatcgcg
      421 aatcatgtca gatataaaat tgcttcttta ctgactgaaa aagtatcttt atcttttatt
      481 gcgaaaaatt gtcaggtatc tttgaccacc gttattcgta cgttgaaaga gtttaaaagc
      541 tacttaccaa agcaatctaa gaggattctc cccagagtat tgatggttga tgaatttcgt
      601 tcgcacgctt ccatagaaga taaaatgagc tttatttgcg cagatggcga aacaggacaa
      661 ttaattgatg tcttgcctac gcgta
//
LOCUS       DAFBVQ010000193          683 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.200, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000193 DAFBVQ010000000
VERSION     DAFBVQ010000193.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 683)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 683)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..683
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.200"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..397
                     /locus_tag="LLC22_002931"
     CDS             <1..397
                     /locus_tag="LLC22_002931"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301867.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436111.1"
                     /translation="HWNAIEGKPTTVKGDKGDPGQAATITIGTVSSGSTASVTNVGTS
                     SAARFNFVLPKGDKGDPGINATTTAVATTTANGLMSSTDKTKLDGIAAGAQKNPGNAT
                     TTTAGLMSATDKVKLDGLANITFEKVGTV"
     gene            397..>683
                     /locus_tag="LLC22_002932"
     CDS             397..>683
                     /locus_tag="LLC22_002932"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002353765.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436112.1"
                     /translation="MADIVQLKEDGVAKYLKTHVEAIDGKEALVQTDGDQAIAGHKNF
                     SGSVTINNKRVLTTDDNRYEVVNLVVTNGNTGTAKLYREGKTVSIYFVALNG"
BASE COUNT          240 a          109 c          160 g          174 t
ORIGIN      
        1 tcattggaat gctatagaag gcaaaccaac aacggtgaag ggagataaag gcgatcctgg
       61 ccaagcagca acaattacca taggaaccgt ttctagtggt tcaaccgctt ctgttacgaa
      121 tgtaggaaca tcatctgcag ctagatttaa ttttgtttta ccaaagggag ataaaggtga
      181 tcctggaata aatgccacaa ctacagctgt agctacaact acagcaaatg ggttgatgtc
      241 gtccacagat aaaactaagt tggatggaat tgcagctgga gcacagaaaa atccaggtaa
      301 tgctacaact acgacagcag gtttaatgtc agcaaccgat aaagtgaaac ttgatggatt
      361 agcgaatatt acatttgaga aagtggggac ggtttaatgg ctgatattgt tcaattaaaa
      421 gaagacggag ttgctaaata cttaaaaacg catgtagaag ctattgatgg taaagaagca
      481 ttggtgcaga cagatggaga ccaagccatt gcaggacata agaatttttc aggttctgta
      541 acaatcaata ataaacgtgt tttgacgact gatgataaca gatatgaagt ggtaaatctg
      601 gttgtcacta acggtaatac agggacagca aagctttatc gtgaaggaaa aacagtttct
      661 atatattttg tggctttaaa cgg
//
LOCUS       DAFBVQ010000194          668 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.201, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000194 DAFBVQ010000000
VERSION     DAFBVQ010000194.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 668)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 668)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..668
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.201"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..165
                     /locus_tag="LLC22_002933"
     CDS             <1..165
                     /locus_tag="LLC22_002933"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347035.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436113.1"
                     /translation="EGYRTPISFEQLVGSIDRSTLNSAQLSIGADGAIKWRRNSSYGS
                     AYSFVITYSI"
     gene            179..610
                     /locus_tag="LLC22_002934"
     CDS             179..610
                     /locus_tag="LLC22_002934"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347165.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436114.1"
                     /translation="MKVVYKSIKPYGFEQIILNNQENIPENCTEIKPPVPNWRPRFDF
                     DKKQWVELATEEEKKGNAVDSVDELANIKALYETLKAENDELKQLNSKAMLNNVAIKQ
                     ENVLLKEKSESLAQLNSKTMLASVQNTKEIEEIKKQLQGGK"
BASE COUNT          260 a          100 c          135 g          173 t
ORIGIN      
        1 gaaggctatc ggacaccaat tagttttgaa caactggttg ggtcaataga ccgttctact
       61 ttgaacagtg ctcaactatc tattggcgca gacggagcca ttaaatggag aagaaattca
      121 agttatggat cagcttattc atttgttatc acttattcaa tttaagggag gaaatctaat
      181 gaaagtagtt tacaaatcaa tcaagcctta cggattcgag caaatcattt tgaacaatca
      241 agaaaatatc cctgaaaact gtacagagat taaaccacca gttcctaact ggagaccaag
      301 atttgatttt gataaaaaac agtgggttga gttagctact gaagaagaga aaaaagggaa
      361 tgctgttgat agcgtagatg aattggctaa tattaaggca ttatacgaaa cgctgaaggc
      421 agaaaatgat gaattgaaac agctaaattc taaagcaatg ctaaacaatg tagcaatcaa
      481 gcaagaaaat gtcttattga aagaaaagtc agaaagttta gcgcagttga attcaaaaac
      541 gatgcttgct tctgtacaaa ataccaagga aatcgaagaa atcaaaaaac aattacaagg
      601 tgggaagtaa catgtattca tatgaagata tcaaactaat gtatgactgg ggctgtttca
      661 ctaacgaa
//
LOCUS       DAFBVQ010000195          650 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.202, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000195 DAFBVQ010000000
VERSION     DAFBVQ010000195.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.202"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>650
                     /locus_tag="LLC22_002935"
     CDS             <1..>650
                     /locus_tag="LLC22_002935"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002339652.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5436115.1"
                     /translation="KSNCGRRPLVLPEEQSEYIQRKVVQGWTPDVIVGRAAFPISCSA
                     RTIYRMFKKGLFDSSDLPMKGKRKPNGHQERRGKQTFRRSIHEREKDYSQFSNEFGHL
                     EGDTIVGLKHKSAVITLVERLSKVIITLKPCGRQAIDIEKKLNQWFESVPKNLFKSIT
                     FDCGKEFSNWKQISNVNDIAIYFADPGTPSQRGLNENSNGLLRRDGLLKSMDFNSV"
BASE COUNT          213 a          112 c          134 g          191 t
ORIGIN      
        1 caaatcaaac tgtggtagac gtccgcttgt tttacccgag gaacaatcag aatatattca
       61 aagaaaggtt gttcaaggat ggacacccga tgtgattgtt ggtcgtgcag cgtttcctat
      121 tagttgttct gctcgtacca tttatcgtat gttcaaaaag gggctatttg attcttctga
      181 cttaccgatg aaaggcaagc gtaaaccgaa tggacatcaa gaaagacgtg gaaaacaaac
      241 tttccgccgc tctattcatg aacgtgaaaa ggattatagc caattctcaa atgagtttgg
      301 tcaccttgaa ggtgacacta tcgtaggtct gaaacataaa agtgctgtaa ttaccttagt
      361 tgaacgatta tcaaaagtta tcatcacatt gaaaccgtgt ggtagacaag cgattgatat
      421 tgaaaaaaaa ttaaatcaat ggtttgaatc tgtaccgaaa aacctattca aatccatcac
      481 ttttgattgt ggaaaggaat tttcaaattg gaaacagatc agtaatgtca atgatattgc
      541 catttatttc gctgatccag gaacgccgtc tcaaagaggc ctaaacgaga attctaacgg
      601 attgttacgt agagatggtt tattgaaatc tatggatttc aattcagtag
//
LOCUS       DAFBVQ010000196          626 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.203, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000196 DAFBVQ010000000
VERSION     DAFBVQ010000196.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 626)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 626)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..626
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.203"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(40..618)
                     /locus_tag="LLC22_002936"
     CDS             complement(40..618)
                     /locus_tag="LLC22_002936"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303152.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436116.1"
                     /translation="MNILFLLLFFLIFLLTYRKCQNYYVRILTALPFFLNLIIYFGNT
                     MGQSFTYVNGNKRAMIWSSSNLNNLFTELGTKLSLFYPGTWIATLVVLALLLCLIVGI
                     YLSFDNKKTSIFLVILMIMGFCSRLIMGFSPTVWASGMRTYYILYVVIAILVLMAVKE
                     LMKSMSVQKNEFMQFGLTVLGICTFIITVINR"
BASE COUNT          241 a          111 c           81 g          193 t
ORIGIN      
        1 atccctcacc taatactaaa gcgagggatt ttttgtatat tatctgttta tcaccgttat
       61 tataaaggta caaataccaa gcacggttaa tccaaattgc ataaattcat ttttttgtac
      121 actcatgctt ttcattagct ctttaactgc cattagtact aagatggcga taacaacata
      181 aagtatatag tacgtccgca ttccggaagc ccatactgtg ggagaaaatc ccataattaa
      241 ccttgaacaa aatcccatta tcatcaaaat aactaaaaaa atagaagttt tcttattgtc
      301 aaaacttaaa taaattccaa caattaaaca tagtaataat gccaagacta ctaaagtagc
      361 tatccaagta cctggataaa aaagtgacag tttcgttcct aactctgtaa agagattatt
      421 caggttacta ctactccaaa tcattgccct tttatttcca ttgacgtaag taaagctttg
      481 acccattgta ttaccaaaat aaataatcag gtttaagaaa aacggtaatg cagtcaatat
      541 acgcacataa tagttttgac atttcctata tgttagaagg aaaattaaga aaaatagcaa
      601 taaaaataag atattcatgt ctaaaa
//
LOCUS       DAFBVQ010000197          598 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.204, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000197 DAFBVQ010000000
VERSION     DAFBVQ010000197.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 598)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 598)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..598
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.204"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(310..>598)
                     /locus_tag="LLC22_002937"
     CDS             complement(310..>598)
                     /locus_tag="LLC22_002937"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342980.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436117.1"
                     /translation="ETQLWFKFDPSNRFIKDFYKVWNSEVFFLAIEDSLLINLYYSNK
                     NYFKIPAAKTRMKKDVYFLFDIVTDVPDARSDHRRYDYIKYTFVDPERYKD"
BASE COUNT          207 a           98 c           90 g          203 t
ORIGIN      
        1 attgtgagat gataataaag aagagtttaa agcgcacccc aagccacttc cccataagtg
       61 tgttacgctt taaactcttt tatatttgaa gctattaaaa ggcataccat atttttgaaa
      121 aaaagtgaga aaaaaggctt acaattggag tggtagttaa ttagtgactt atttttgatt
      181 ttatagcact gatactataa aatatagata tcatcatatt acacaatctt aatactaact
      241 taaaaaatat ctcctttcac aagtatggtg ataaaattcg ttccgggcta cctttttagg
      301 tagcctactt taatctttgt atctttctgg atcaacgaaa gtatacttta tatagtcata
      361 acgccgatga tcgctacgtg cgtccggcac gtcagtcacg atatcaaaca aaaagtatac
      421 atccttcttc attctagttt tcgcagcagg aattttgaaa tagttcttat tagaatagta
      481 gagattgatt aataagctat cttcgattgc taaaaagaaa acttctgaat tccatacttt
      541 ataaaaatct ttgataaatc tattcgaagg gtcaaattta aaccataatt gtgtctca
//
LOCUS       DAFBVQ010000198          577 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.205, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000198 DAFBVQ010000000
VERSION     DAFBVQ010000198.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 577)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 577)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..577
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.205"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(138..491)
                     /gene="tnpB"
                     /locus_tag="LLC22_002938"
     CDS             complement(138..491)
                     /gene="tnpB"
                     /locus_tag="LLC22_002938"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001846105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS66 family insertion sequence element accessory
                     protein TnpB"
                     /protein_id="HBK5436118.1"
                     /translation="MLYDLLQTKHIYIVCGKTDLRKGIDGLASLIQQEYQLELYEDAV
                     FLFCGNRQDRFKLLYWDGDGFLLCYKRIENGKLKWPRTKDEVRTLTNQQVRWLLEGLS
                     IDQPRAILPGKKGVF"
BASE COUNT          183 a          123 c           93 g          178 t
ORIGIN      
        1 ttgaagcaac tgaagcaacg tatctgtagt ttccaaaatt tttcaccacc ttgaatcgaa
       61 ctgattttgt tacagaatac cacaagaaac gcacaagaaa taggggttca acacattttt
      121 tgtgttaacc ccccagctta aaaaactcct ttttttcctg gcaaaatagc tcgaggttga
      181 tcgatactta atccttctaa caaccatcga acctgttggt tcgttaaggt tcgaacttcg
      241 tctttcgtcc gaggccattt taacttgccg ttttctatcc gcttataaca gagaagaaaa
      301 ccatcaccgt cccaatagag aagtttgaaa cggtcttgac ggttcccgca aaataaaaaa
      361 acggcatctt cgtaaagctc gagttgatac tcttgttgaa taagactggc aagaccatca
      421 attccttttc gcaaatctgt ttttccgcac acaatataaa tatgtttggt ttgaagtaaa
      481 tcataaagca ttggacaaca gttctttcaa aatagcttga agaatataat tgttaatacc
      541 gttatagatc aaaacttcag aaccattctc tcttttg
//
LOCUS       DAFBVQ010000199          569 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.206, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000199 DAFBVQ010000000
VERSION     DAFBVQ010000199.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 569)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 569)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..569
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.206"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            312..>569
                     /locus_tag="LLC22_002939"
     CDS             312..>569
                     /locus_tag="LLC22_002939"
                     /inference="COORDINATES: protein motif:HMM:NF012870.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase family protein"
                     /protein_id="HBK5436119.1"
                     /translation="MSAVVTDLTYVRVGTNWAYICLMIDLFNREIIGHSCGNKKDAQL
                     VKRAIQSIPYSLQEIELFHTDRGKEFDNQTIQNLMNGLVIKF"
BASE COUNT          195 a          102 c           82 g          190 t
ORIGIN      
        1 ttttacactc tctattattc ttttcataaa tattgtaaat agaagtatta aaaatatata
       61 caaaaagtat tatttcgaga aagataaata ttttcaaaaa ccttttcata atcctcaccc
      121 tttcttacac tgataaatca tgcgtctaat attcaaatta tactcgatat gctttagcta
      181 atcagccaac tctgtttgtc tactatcatt atatcaatag acaatatctg ctcccgtctt
      241 tatgatcgtg ccaaagcaat caaaagaaaa ttgcgaatca cttagatcga aagtttactc
      301 aaacaaaagc attgtcagcg gttgtcacgg atttaactta tgttcgggtc gggacaaatt
      361 gggcttatat ttgtttgatg attgatttat tcaatcgtga aattattggc cattcttgcg
      421 gaaataaaaa agatgcgcag cttgtaaaaa gggccattca aagcattcct tactcacttc
      481 aagaaatcga actcttccat acggatcgtg gaaaagaatt tgataaccaa accattcaga
      541 atctcatgaa tggtttggtt atcaaattc
//
LOCUS       DAFBVQ010000200          550 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.207, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000200 DAFBVQ010000000
VERSION     DAFBVQ010000200.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 550)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 550)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..550
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.207"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            33..>550
                     /locus_tag="LLC22_002940"
     CDS             33..>550
                     /locus_tag="LLC22_002940"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS256-like element ISEf1 family transposase"
                     /protein_id="HBK5436120.1"
                     /translation="MNDFTTEIVQTLVTKGDLNELFRSHLEKAINTLLRTELTAFLDY
                     EKYDRTGFNSGNSRNGSYFRSIKTEYGELTLEIPRDRNGEFKQQTLPAYKRTNDTLET
                     TIIHLFEKGVTMSEIADLIEKMYGHHYTPQTMSNMTKVLTEEVNAFKSRALNDKYVAI
                     FMDATYIPLKRQT"
BASE COUNT          203 a          105 c           88 g          154 t
ORIGIN      
        1 gacaaccaat tcacagaaaa gaggacttcc ctatgaatga ttttactaca gaaattgtgc
       61 aaactctagt cactaaaggc gatttaaatg aattattccg ttcgcactta gaaaaagcga
      121 taaacacact cctacggact gaattaacgg cttttttaga ttacgaaaaa tatgatcgca
      181 ctggttttaa ttcaggtaat tcgagaaacg gttcttactt tcgatcaatc aaaaccgaat
      241 atggtgaatt aacattggaa atacctagag atcgtaatgg tgagtttaaa caacaaactt
      301 taccagccta caaaagaaca aacgatacat tggaaaccac tattatccat ttattcgaaa
      361 aaggtgttac gatgtctgaa attgctgatt tgatcgaaaa aatgtacggt catcactata
      421 ctccacaaac catgtccaac atgactaaag ttctgactga agaagtaaat gcctttaaat
      481 ccagagcctt aaatgataag tatgtcgcta tttttatgga cgctacttac attccactaa
      541 aacgtcaaac
//
LOCUS       DAFBVQ010000201          548 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.208, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000201 DAFBVQ010000000
VERSION     DAFBVQ010000201.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 548)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 548)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..548
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.208"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>548
                     /locus_tag="LLC22_002941"
     CDS             <1..>548
                     /locus_tag="LLC22_002941"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002297185.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ISL3-like element ISEfa5 family transposase"
                     /protein_id="HBK5436121.1"
                     /translation="DRFHIIKHMNQAFNELRIREMNELRKVGQKSQAEKLKKNWRFLL
                     KNRANINHYEYKTWKSFRAPKYPFLTEAMMIDRLLGFSTSLKEAYPYFHELVEAFRDK
                     DPDLFFSLLAELPETLDDGFREKLQNLLTYEEGITNAMIYPYTNGKIEAKNTHIKTMK
                     RVSYGFKSFENMRIRIFLINQL"
BASE COUNT          194 a          106 c          101 g          147 t
ORIGIN      
        1 gatcggtttc atattatcaa acacatgaat caagccttta atgagttgcg tatccgtgaa
       61 atgaatgaac ttcgtaaagt aggacagaaa agtcaggcag aaaaactgaa aaagaactgg
      121 cgctttttgc taaaaaatcg tgcaaacatc aaccattatg aatacaaaac atggaaaagt
      181 tttcgagcac caaaataccc atttcttacg gaagcgatga tgattgatcg attgcttggc
      241 ttttctacgt ccctgaagga ggcgtatccc tattttcatg aattagttga agcctttcga
      301 gacaaagacc ctgacttatt tttctcctta ttggcagaac ttcccgaaac gttagatgac
      361 ggctttcggg aaaagctcca aaaccttctg acctatgaag aaggcatcac caacgcgatg
      421 atctatcctt acaccaatgg aaaaatagaa gcgaagaata cccatataaa gacaatgaaa
      481 cgagtatcct acggatttaa atcatttgag aacatgagaa ttagaatctt tttgatcaat
      541 caattaat
//
LOCUS       DAFBVQ010000202          546 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.209, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000202 DAFBVQ010000000
VERSION     DAFBVQ010000202.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 546)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 546)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..546
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.209"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(271..534)
                     /locus_tag="LLC22_002942"
     CDS             complement(271..534)
                     /locus_tag="LLC22_002942"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002300807.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="uberolysin/carnocyclin family circular
                     bacteriocin"
                     /protein_id="HBK5436122.1"
                     /translation="MKKNLLLVLPILGFAGFFVGVPMLSANIGISSYAAKKVIDIINT
                     GSTVATIISIVAAVVGGGLITAGIVATAKSLIKKYGAKYAAAW"
BASE COUNT          213 a           97 c           75 g          161 t
ORIGIN      
        1 actctcctga attttttcat gttgaaaaca tcactaatca aaggcaaatt ataatttaga
       61 aatagaatga aaacactaaa tgaaaataga acattagaaa aaatagaatc aaaaaaaccc
      121 aagactagtg ccgaaataag ggaaacaatc gaagctacaa aaaataatga tttcgttgaa
      181 caggaccaat ttatttgttt ccgatatttc tcaaaaagaa ctttctttgg gaaagttaaa
      241 ggcgactgta aagtcgcctt tagtcctttt ttaccaagct gctgcatatt tagctccata
      301 ttttttaatt aatgatttgg ctgtagcaac aataccagct gtaattaatc cgcctccaac
      361 aactgcagca acaatagaaa tgattgtagc aaccgtgcta ccagtattaa ttatgtcaat
      421 aactttttta gctgcataag aagaaattcc aatgttagca cttagcattg gtacaccaac
      481 aaagaatccc gcaaaaccta aaattggtaa aactaataat aaattctttt tcataataat
      541 tcctct
//
LOCUS       DAFBVQ010000203          514 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.210, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000203 DAFBVQ010000000
VERSION     DAFBVQ010000203.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 514)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 514)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..514
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.210"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..132)
                     /locus_tag="LLC22_002943"
     CDS             complement(<1..132)
                     /locus_tag="LLC22_002943"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_014748673.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS110 family transposase"
                     /protein_id="HBK5436123.1"
                     /translation="MKLFVGIDVSSEKLDVCFLTDDNQLSILSEISVANDIEGASFIR
                     "
BASE COUNT          186 a           94 c           92 g          142 t
ORIGIN      
        1 tcgtatgaat gaagcacctt cgatgtcatt ggcaacagag atttcagata agatagacaa
       61 ttgattgtcg tctgttaaaa aacaaacatc tagtttttca gagctaacgt caataccgac
      121 aaataatttc atggaagaag gacctccttt cgatataaat tttggaaaat gcttcgatac
      181 tgtgggattt cccagaaact cactgtatag ccacaacctc gcctaataga atacggtgat
      241 aaaagagcta gaagctgcct tccaaactac tatttgaaag tctagtccat tatcgaaaca
      301 gctaatgagt tggtagtgat aacagtggtt cgggtaacag actaaacagg gtagacaaac
      361 gctacaggag gaaatagcaa attcccgttg gatcctttcc atacatccat tgtactctga
      421 gaaatcacac aatatcgaaa caaattccgt taggaatgtg ttattcaata aattttataa
      481 tctagaaaca ttttgaataa aaactattag acaa
//
LOCUS       DAFBVQ010000204          509 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.211, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000204 DAFBVQ010000000
VERSION     DAFBVQ010000204.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 509)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 509)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..509
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.211"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
BASE COUNT          228 a           70 c           81 g          130 t
ORIGIN      
        1 aattccttag gcagcttttg ctgtgtagaa aggaataaat aataacgaaa gttcaaaagc
       61 taatgccgac tattctagac attaaagaag acgaaaacga acgataaaga aagaaaagtt
      121 atgaataatc gtttattgaa aaaaacttga aaaaatacaa aaaattcgtt gaccaagcta
      181 aatttagttg gtatattatt acttgtccaa aagacagaag aaaatattta ttcaaaaaca
      241 taacaaaaaa gttattgaca tgttactaac gacatgataa gataactgag tcgttaaaaa
      301 agaaccactt gcgaagcttg attctatcga aaaaaacttc aaaaaagttc ttgacaaata
      361 acaaacgata agttatgata aatgagttgc cgaaagattt cgaaaaacga aatcgaaaaa
      421 aacttttaaa aaagagttga caatcgcttg tctctctgat atgatataaa agttgctacg
      481 gcagccaaaa atgaatcggg aaacactct
//
LOCUS       DAFBVQ010000205          505 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.212, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000205 DAFBVQ010000000
VERSION     DAFBVQ010000205.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 505)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 505)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..505
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.212"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>505
                     /locus_tag="LLC22_002944"
     CDS             <1..>505
                     /locus_tag="LLC22_002944"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611882.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS982-like element ISEfm1 family transposase"
                     /protein_id="HBK5436124.1"
                     /translation="RQAKLLNQIAKVGYNSTKKSYFYGLKIHMIVTKTGFPITYSITN
                     PGVHDVKVLETLSEEANLPNILGDKGYISHKIHEKLALKGITISVPPRKNMDKSEKLD
                     HSLLGKQRKTVETVFSSLEKLGCQNFNSRSVKGLESRFESILLAYSVLLSRAQRRFEG
                     TLRYSLGY"
BASE COUNT          180 a           89 c           90 g          146 t
ORIGIN      
        1 tagacaagca aaactattga atcaaatagc caaagttggc tataactcaa caaaaaaatc
       61 ttatttttat ggtcttaaaa ttcatatgat cgttactaag actggctttc cgattactta
      121 ctcaatcacg aatccaggtg tccatgacgt gaaagtgtta gagactttat cggaagaagc
      181 gaatcttccc aatatcctag gggacaaagg atatattagc cataaaatcc atgaaaagct
      241 tgcccttaag ggcattacta tatccgttcc gccacgtaaa aacatggata aatcagaaaa
      301 actagaccac agcttacttg gaaaacaaag aaaaacagtt gagactgttt tttcttcctt
      361 agaaaaatta ggttgtcaaa atttcaactc acgttctgtt aaagggctag agagtagatt
      421 tgaaagcata ttactggctt acagtgttct attaagtcga gcacaacgac gttttgaagg
      481 aactttgaga tattctttag gatat
//
LOCUS       DAFBVQ010000206          498 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.213, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000206 DAFBVQ010000000
VERSION     DAFBVQ010000206.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 498)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 498)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..498
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.213"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(75..272)
                     /locus_tag="LLC22_002945"
     CDS             complement(75..272)
                     /locus_tag="LLC22_002945"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002342557.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cold-shock protein"
                     /protein_id="HBK5436125.1"
                     /translation="MNNGTVKWFNSDKGFGFITGEDGNDVFAHFSAIQGEGFKSLDEG
                     QAVTYDIEEGQRGPQAVNIVK"
BASE COUNT          162 a           90 c           72 g          174 t
ORIGIN      
        1 atattacggt gaggaatttt ttctaccgac ataaacaaaa aaaccacctc atatgaggcg
       61 gttaacgttc aacattattt tacgatattt actgcttgag gaccacgttg tccttcttca
      121 atatcataag taactgcttg gccttcatct aaagacttaa agccttctcc ttggattgct
      181 gagaaatgag cgaatacgtc atttccatct tcaccagtga tgaaaccaaa acctttatct
      241 gagttaaacc attttactgt accgttattc atatatattt cctcctgata cgtatataat
      301 acgtgtttta ttgcaattaa tattacttgg taaaaggagt ttttatagtg tgaatatatc
      361 gctcagatta cgtttcaaat tagattactt atttactata acacggatgt aatgctaaca
      421 caaggataat cactcgatat acggtttaaa tattattatt tgtcaaatta agcgagacaa
      481 aactttccat ttacgtaa
//
LOCUS       DAFBVQ010000207          490 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.214, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000207 DAFBVQ010000000
VERSION     DAFBVQ010000207.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 490)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 490)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..490
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.214"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
BASE COUNT          161 a           94 c           75 g          160 t
ORIGIN      
        1 acactcctct taatatacag tcctattgta taaagtgtta ctatatacat agtaactgta
       61 tacataaaaa aagtcaagta ttagaaaaaa gttcaaaaga tcaagtgtgc gcttcgctcc
      121 cactcccctc gacgttttag tagcctttcc ctcacttcgt tcagtccaag ccaactaaaa
      181 agttttcggg atacattctc cttctcttcc taataatcaa ttaaaatttt aatctttata
      241 tttctgctaa tcactcagga aacagtacag aaaaacaaac acgtatcata gatataaatg
      301 taatggcata gtgcgggttt tattttcagc ctgtatcata gctaaacaaa tcgagttgtg
      361 tgtccgtttt tgggcgttct gctagcttgt ttaaagtctc ttgaatgaat gtatgttcta
      421 agtcaaaaaa ctctgacagc gcctttatat agataaagtc cgtataattg tgtaaaagta
      481 aaaaggccat
//
LOCUS       DAFBVQ010000208          489 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.215, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000208 DAFBVQ010000000
VERSION     DAFBVQ010000208.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 489)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 489)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..489
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.215"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            68..>489
                     /locus_tag="LLC22_002946"
     CDS             68..>489
                     /locus_tag="LLC22_002946"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5436126.1"
                     /translation="MTYTHLTPNELVMIEAYFHQETPVAIVAKQLKRGRQTIYNVYNF
                     LKCGGTALEYFEQYKENKRRCGRTEIIFPAEEKEYIEKRSTEGWTPDVIIGRAERTFS
                     CSVSTLYRRFKTGEFNVLHLPMQGKRKPNGYKEKRGKQA"
BASE COUNT          179 a           94 c           96 g          120 t
ORIGIN      
        1 aaaaaagcca tttatgttac actcaaattg taatacccgc taaagcatac aaggagagtg
       61 aacataaatg acttataccc atcttacacc aaacgagctt gtaatgatag aagcatattt
      121 tcatcaagaa actccggttg ctatcgttgc gaagcagctt aaacgtggac gccaaacaat
      181 ttacaatgtc tataactttc tcaaatgtgg tggaacagca cttgaatact ttgaacaata
      241 caaagaaaat aagcgacgtt gtgggagaac cgaaatcatt tttcctgctg aggaaaaaga
      301 atacattgaa aaaagatcaa ctgaaggttg gaccccagac gtcattattg gccgtgcaga
      361 gcgaaccttc tcttgttcag taagtaccct ctatcgccgg tttaagacgg gagaattcaa
      421 tgttttacat ttaccgatgc aaggaaaacg aaaaccaaat ggttataagg aaaaacgtgg
      481 aaaacaggc
//
LOCUS       DAFBVQ010000209          488 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.216, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000209 DAFBVQ010000000
VERSION     DAFBVQ010000209.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 488)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 488)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..488
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.216"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..414)
                     /locus_tag="LLC22_002947"
     CDS             complement(<1..414)
                     /locus_tag="LLC22_002947"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321168.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436127.1"
                     /translation="MGETGWRATTLNYQWPVAFSLLTFYPFFQLLRGEEINRKIYWVS
                     IPLLIFLTNQEQVNACFFVLTSIVSLYLIVNGRYNYKLSVFSIISLAELIFSLTTPGN
                     ALRAAHEINKWFPEYKNFNFLNKLDLGISSFGKPFF"
BASE COUNT          185 a           78 c           62 g          163 t
ORIGIN      
        1 aaaaaacggc tttccaaatg atgaaatacc taaatctaac ttattaagaa agttgaaatt
       61 tttatattca ggaaaccatt tattaatttc atgtgcagca cgtaatgcat tccctggagt
      121 tgtcaaagag aaaattaatt ctgctaagct tattattgaa aatactgata acttataatt
      181 atatcgtcca ttgacaatca aatataaact aactatactt gttagaacaa aaaaacaggc
      241 gttgacttgt tcttgattag ttaaaaatat caataaagga atacttaccc aatatatttt
      301 tctatttatt tcttctcctc ttaagagttg aaaaaacgga taaaaagtta gtaaactaaa
      361 tgctactggc cactgatagt tcaaggtggt tgctctccaa ccggtttccc ccattactgt
      421 caatggtatt aaacagtata tagagcaaac caataataaa tttttaacat ttattttctc
      481 aaaaacat
//
LOCUS       DAFBVQ010000210          487 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.217, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000210 DAFBVQ010000000
VERSION     DAFBVQ010000210.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 487)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.217"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..>487)
                     /locus_tag="LLC22_002948"
     CDS             complement(<1..>487)
                     /locus_tag="LLC22_002948"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DDE-type integrase/transposase/recombinase"
                     /protein_id="HBK5436128.1"
                     /translation="IHRRFYTSICHQKITTDTTEFKYHEVDAKGIIRQKKLYLDPFMD
                     MFNSEILSYRISEKPNALAVMEGLEEAIQTTNDCPYRRTFHSDQGWAYQMKAYRNKLK
                     EYKIFQSMSRKGNCLDNSLMENFFGLLKQEIFHGKVYNCFEELKSAIDSYIYYYNNER
                     IK"
BASE COUNT          142 a           92 c           86 g          167 t
ORIGIN      
        1 gttttatccg ttcattattg tagtaataga tatagctatc gatggctgat tttaattcct
       61 cgaaacagtt ataaactttc ccgtgaaaaa tctcttgttt taataagcca aaaaaattct
      121 ccataagtga attatctaag cagttccctt tccgagacat gctttgaaag attttgtact
      181 ccttcaattt gtttctataa gctttcattt gatacgccca accttgatct gagtgaaacg
      241 tacgacgata gggacaatcg ttagtggtct ggatagcttc ctccaaacct tccattaccg
      301 ctaatgcatt gggcttttca gagatacgat aggataaaat ctcactattg aacatatcca
      361 taaaaggatc tagatacaat ttcttttgac ggataatgcc tttggcatcc acttcatggt
      421 atttaaattc agttgtatcc gtcgtgattt tctgatggca gatactggtg tagaaacgac
      481 gatggat
//
LOCUS       DAFBVQ010000211          481 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.218, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000211 DAFBVQ010000000
VERSION     DAFBVQ010000211.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 481)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 481)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..481
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.218"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>481
                     /locus_tag="LLC22_002949"
     CDS             <1..>481
                     /locus_tag="LLC22_002949"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250137.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436129.1"
                     /translation="TFTAGEGTSIESGTTVFAVKDGVSLPEDKLPVLKAKDGYTDAKW
                     PEEATQPITADDTEFVSSATKLDDKSDADKYNPEGQKVTTELNKEPDAFEGIKNKEDL
                     PKDTKYTWKEKVDVSAAGNKKGTVVVTYPDGSSDEVEVDVTVTDNRSDADKYEPTVEG
                     "
BASE COUNT          194 a           74 c          112 g          101 t
ORIGIN      
        1 taaccttcac cgcaggagaa ggaacaagta ttgaaagtgg aacaacagtc tttgcagtga
       61 aagacggcgt aagcttacca gaagataaac ttccagtgtt gaaagcaaaa gatggttata
      121 cagatgcgaa atggccagag gaagcaactc aaccaattac agcagatgat acagaatttg
      181 tatcaagtgc aacaaaactg gatgataaat ctgacgctga caaatataat cctgaaggtc
      241 aaaaagtgac tacagaattg aataaggaac cagacgcatt tgagggaatt aagaacaaag
      301 aagatttacc aaaagatact aagtatactt ggaaagaaaa agtagatgtt agcgcagctg
      361 gaaataaaaa agggactgtt gtagtgacat atccagatgg atcatctgat gaagttgaag
      421 tagatgttac agtgacagac aatcgttctg acgccgataa atatgagcca acagtagaag
      481 g
//
LOCUS       DAFBVQ010000212          467 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.219, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000212 DAFBVQ010000000
VERSION     DAFBVQ010000212.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 467)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 467)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..467
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.219"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            1..467
                     /locus_tag="LLC22_002950"
                     /pseudo
     CDS             1..467
                     /locus_tag="LLC22_002950"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558187.1"
                     /note="frameshifted; incomplete; missing N-terminus and
                     C-terminus; Derived by automated computational analysis
                     using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS3-like element IS1485 family transposase"
BASE COUNT          191 a           84 c           87 g          105 t
ORIGIN      
        1 tctaagagaa cacgaagaac tttttcacaa gaattcaagc aacaaatcgt caatctttac
       61 ttagctggaa agccacgtgt agaaatcatt cgagaatatg aactaacggc ttcagcattt
      121 gacaaatggg taaagcaatc taaaacgagt ggttcattca aagaaaaaga taatcttacg
      181 cctgaacaaa aagaattgtt agaactacgt aaaagaaacc agcaattaga aatggaaaat
      241 gatattttaa agcaagcagc gctgatattc ggacgaagag acaagtaatc gatgcgaata
      301 agcatcttta ccctatatca gcgatgtgca gaatattagg tctatcacgt cagtcctatt
      361 attatcaatc aaaaccaaag aaagacgaat cagaacttga agaagtagtc gctgaagaat
      421 ttatccgcag ccgaaaggcc tacggctcaa gaaaaataaa aaaagcc
//
LOCUS       DAFBVQ010000213          415 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.220, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000213 DAFBVQ010000000
VERSION     DAFBVQ010000213.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 415)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 415)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..415
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.220"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..339)
                     /locus_tag="LLC22_002951"
     CDS             complement(<1..339)
                     /locus_tag="LLC22_002951"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002349331.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5436130.1"
                     /translation="MEQLKAYKFRIYPTEEQEIFFAKSFGCVRKVYNLMLDDRKKAYE
                     EVKNDSSKKMTFPTPAKYKKEFPFLKEIDSLALANAQLNLDKAYKNFFRDKSVGFPRF
                     KSKKNPVQSYT"
BASE COUNT          116 a           70 c           68 g          161 t
ORIGIN      
        1 tgtataactc tgaacaggat ttttcttact tttgaaacgt ggaaatccaa cggatttatc
       61 ccgaaaaaaa ttcttgtatg ctttatctaa attaagttgg gcattggcta aagcaaggct
      121 atcaatttct ttcaaaaacg gaaattcttt cttgtattta gctggtgtcg gaaaagtcat
      181 ttttttagaa gaatcatttt taacttcttc atacgccttt tttcggtcat caagcattag
      241 attgtagacc ttacggacac aaccaaaaga tttggcaaag aagatttctt gttcctctgt
      301 tggatagatt ctgaatttgt atgcttttag ttgttccata aagttcacct actttctatt
      361 tatgattgtt tccttgattt tggatatact tcttaatcac atcaattggt gcgcc
//
LOCUS       DAFBVQ010000214          405 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.221, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000214 DAFBVQ010000000
VERSION     DAFBVQ010000214.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 405)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 405)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..405
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.221"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..382
                     /locus_tag="LLC22_002952"
     CDS             <1..382
                     /locus_tag="LLC22_002952"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000997695.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5436131.1"
                     /translation="KEICDDFKAVYQANSKEEANTFLSGMIEKWKKNYPKVTQSLIEN
                     QDLLTFYDFPPSIRRTIYSTNLIESFNKQIKRYSRRKEQFQNEESLERFLVSIFDTYN
                     QKFLNRSHKGFQQVTDTLVSMFTE"
BASE COUNT          157 a           72 c           63 g          113 t
ORIGIN      
        1 aaaagaaatc tgtgatgact ttaaggctgt ttatcaagct aactcaaaag aagaagcgaa
       61 taccttctta tccggcatga ttgagaaatg gaagaaaaac tatcctaaag tgacgcagtc
      121 actcatagaa aaccaagact tattaacttt ttatgatttt ccacctagca ttcgtagaac
      181 catttactca accaatctaa tcgagtcttt caataagcaa attaaaagat acagccgtag
      241 aaaagagcag tttcaaaatg aagaatcact agaacgcttt ctagtcagca tttttgatac
      301 atacaatcaa aaatttctaa acagaagcca taaaggtttt caacaggtaa ccgatacatt
      361 agtttcaatg tttactgagt aactaattat tttgcaggag gacaa
//
LOCUS       DAFBVQ010000215          390 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.222, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000215 DAFBVQ010000000
VERSION     DAFBVQ010000215.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 390)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 390)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..390
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.222"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(91..>390)
                     /locus_tag="LLC22_002953"
     CDS             complement(91..>390)
                     /locus_tag="LLC22_002953"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611768.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5436132.1"
                     /translation="HEILNGFGITRSLSRKGCPYDNAVVESTYKSVKVEFVHQYQFET
                     LAQLRLELFDYVHWWNYLRLHGTLAYETPIQIRQQRLAKRILDNERGSDTSGEAA"
BASE COUNT          104 a           96 c           76 g          114 t
ORIGIN      
        1 ttgtgaatgc tgcggtgtta tggctccgat tgcccttgac aatgagcatc ctcggatctg
       61 attttctccg gcagaagcac aatcattcaa ttacgctgcc tctccagagg tatcagatcc
      121 gcgctcatta tcaaggattc gcttcgccaa tctctgttgt cgaatttgga tcggtgtttc
      181 atacgccaac gtgccatgta agcgtagata gttccaccaa tgcacataat caaacaattc
      241 tagacgtagc tgtgccagtg tctcaaattg gtattgatgc acgaattcta ctttgacaga
      301 tttataggtt gattccacaa cggcattatc atacggacaa cccttcctac tcaatgaacg
      361 agtaattcca aaaccattca gaatctcatg
//
LOCUS       DAFBVQ010000216          368 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.223, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000216 DAFBVQ010000000
VERSION     DAFBVQ010000216.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 368)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 368)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..368
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.223"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            97..>368
                     /locus_tag="LLC22_002954"
     CDS             97..>368
                     /locus_tag="LLC22_002954"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436133.1"
                     /translation="MINLGEWGAIAGSITAIVSLILLVIKPITASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHAEKLVEHTQQIKT"
BASE COUNT          140 a           53 c           69 g          106 t
ORIGIN      
        1 tatgcattac agacgaagaa gcagataaaa tcattagcaa agaagagagc gcatcttaat
       61 tgatgtgctt tttattttga ttcaaggagt tgtcacatga ttaatttagg ggaatgggga
      121 gcgatagcag gatcaataac cgctatcgtt tctttgattt tattagtaat aaaaccaatt
      181 actgcatctt tctcgaagat tactgagact ctttcaaaag taagtcacaa tttagatttg
      241 ctgactaaag atttagaatc gagcaaatca gatcgattga tgattcatga agaactaaag
      301 aaacacgatg aaagattaga tacacatgca gaaaaattgg tagaacacac gcaacaaatt
      361 aaaacttt
//
LOCUS       DAFBVQ010000217          367 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.224, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000217 DAFBVQ010000000
VERSION     DAFBVQ010000217.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 367)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 367)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..367
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.224"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..272)
                     /locus_tag="LLC22_002955"
     CDS             complement(<1..272)
                     /locus_tag="LLC22_002955"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002341747.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436134.1"
                     /translation="MINLGEWGMIAGSITAIVSLILLVIRPIAASFSKITETLSKVSH
                     NLDLLTKDLESSKSDRLMIHEELKKHDERLDTHTEKLVEHTQQIKT"
BASE COUNT          105 a           69 c           52 g          141 t
ORIGIN      
        1 aaagttttga tttgttgcgt gtgttccacc aatttttctg tatgtgtatc taatctttca
       61 tcgtgtttct ttagttcttc atgaatcatc aatcgatctg atttgctcga ttctaaatct
      121 ttagtcagca aatctaaatt gtggcttact tttgaaagag tctcagtaat tttcgagaaa
      181 gatgcagcaa tcggtctaat tactaataaa atcaaagaaa cgatagcggt tattgatcct
      241 gctatcattc cccattcccc taaattaatc atgtgacaac tcctttacct taaataaaaa
      301 cgcatcaatt aagatgcgct cttatcttta ttaatgattt tatctgcttc ttcgtctgta
      361 atgcata
//
LOCUS       DAFBVQ010000218          362 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.225, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000218 DAFBVQ010000000
VERSION     DAFBVQ010000218.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.225"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>362
                     /locus_tag="LLC22_002956"
     CDS             <1..>362
                     /locus_tag="LLC22_002956"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301865.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage baseplate upper protein"
                     /protein_id="HBK5436135.1"
                     /translation="MQCLHRQTANFIIFKGEDLIGTTQDFSYFVINAVSKTEGEMGSY
                     WQSIEDLIADMTDFINENKGDFTDWMNERKEEFDRWREEQENSFQDWREGQESDYLSW
                     FESIKDILKSIDPGGVMLA"
BASE COUNT          130 a           44 c           82 g          106 t
ORIGIN      
        1 atgcagtgtt tgcatcgaca aacagccaat ttcattatat ttaaaggaga agacttgatt
       61 ggaacaactc aagacttctc ctattttgtc atcaatgctg tttcaaaaac agaaggagaa
      121 atgggttctt attggcaatc aattgaagat ttaattgctg atatgacaga ttttattaat
      181 gaaaataaag gcgattttac ggactggatg aatgaaagga aagaagaatt tgatcgctgg
      241 agagaagaac aggagaatag tttccaagat tggagagaag gacaagaatc agattatttg
      301 tcatggtttg aatcaatcaa ggatattttg aagtctatcg atccaggtgg agtaatgtta
      361 gc
//
LOCUS       DAFBVQ010000219          362 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.226, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000219 DAFBVQ010000000
VERSION     DAFBVQ010000219.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 362)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 362)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..362
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.226"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>362
                     /locus_tag="LLC22_002957"
     CDS             <1..>362
                     /locus_tag="LLC22_002957"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_012477736.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6-like element ISS1D family transposase"
                     /protein_id="HBK5436136.1"
                     /translation="RWVQEYSKVLYYLWKKKNRQSFYSWKMDETYIKIKGRWHYLYRA
                     IDADGLTLDIWLRKKRDTQAAYAFLKRLHKQFGEPKAIVTDKAPSLGSAFRKLQSVGL
                     YTKTEHRTVKYLNNLIEQ"
BASE COUNT          122 a           67 c           77 g           96 t
ORIGIN      
        1 cgttgggtgc aagagtacag caaagtcctc tattatcttt ggaagaagaa aaatagacaa
       61 tccttctatt catggaaaat ggacgaaacc tatatcaaaa ttaagggacg ttggcattat
      121 ctttatcgtg caattgatgc ggacggctta accttagata tctggttacg aaagaaacgg
      181 gatacgcaag cagcctatgc tttcttaaaa cgactccata aacagtttgg tgagccgaaa
      241 gcaattgtga ccgataaagc accttctctt ggctccgcct ttagaaagtt acagagtgtg
      301 ggtttatata ctaagacaga gcaccgaact gtgaagtatc ttaacaattt aatagaacaa
      361 ga
//
LOCUS       DAFBVQ010000220          360 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.227, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000220 DAFBVQ010000000
VERSION     DAFBVQ010000220.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 360)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 360)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..360
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.227"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..233
                     /locus_tag="LLC22_002958"
     CDS             <1..233
                     /locus_tag="LLC22_002958"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_076611665.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5436137.1"
                     /translation="LKNLPETLDAQLRTKLQNLLTYEEGIYNAMIYPYSNGKIEAKIP
                     HIKTLKRLSYGFKSFENMKIRIFLINQLIQVK"
BASE COUNT          135 a           63 c           51 g          111 t
ORIGIN      
        1 tattaaaaaa tcttcctgaa acacttgatg cacaacttcg cacgaaactt caaaaccttt
       61 taacgtatga agaaggtatt tacaatgcta tgatttaccc gtattctaat ggcaaaatag
      121 aggccaagat tccccatatc aagacactga aacgattatc ttatggattt aaatcatttg
      181 agaacatgaa aatcaggatt tttttgatca atcaattgat tcaagtgaaa taacaaaaaa
      241 atctgagaca gaaggtcagt ccttctatcg gctctatact ttttgatgtt ggtgaacttc
      301 accaacatct tttttgtata aaaaaatata gaaaagacac cctgaaatcc tttagaatta
//
LOCUS       DAFBVQ010000221          354 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.228, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000221 DAFBVQ010000000
VERSION     DAFBVQ010000221.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 354)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 354)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..354
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.228"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(1..152)
                     /locus_tag="LLC22_002959"
                     /pseudo
     CDS             complement(1..152)
                     /locus_tag="LLC22_002959"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347711.1"
                     /note="internal stop; incomplete; partial in the middle of
                     a contig; missing N-terminus and C-terminus; Derived by
                     automated computational analysis using gene prediction
                     method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
BASE COUNT          122 a           69 c           44 g          119 t
ORIGIN      
        1 gtgatgacgg cacttttatg gtggatgccg acaatcgtat caccctctaa atgtccaaat
       61 tcttcttcga aaacgacata atctttttta cgctcagaaa tatttctttt gaatgcctgt
      121 tttccacgtt tttccttata accatttcat tgtgatccac ctcttttgtt tattagttta
      181 aaccatcaaa ccatttttaa taaaatatgt aaattccttt gctcaaaaaa gtagcttctt
      241 tacgattcga caatttcaaa taaagcaggt aaaaactggc tgtcagaaaa tagccaaact
      301 gaagcaaaaa ataatgttaa aattaattaa tgaacgaaaa aaatccctca ccta
//
LOCUS       DAFBVQ010000222          337 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.229, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000222 DAFBVQ010000000
VERSION     DAFBVQ010000222.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 337)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 337)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..337
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.229"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            122..328
                     /locus_tag="LLC22_002960"
     CDS             122..328
                     /locus_tag="LLC22_002960"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002301818.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage holin"
                     /protein_id="HBK5436138.1"
                     /translation="MNNRTFDILKWIAIVVIPALATFVGLVGKGVNWRYTDITVMIIT
                     GFGAFLGSILGVSNRTYKKISSDK"
BASE COUNT          120 a           43 c           82 g           92 t
ORIGIN      
        1 gataaaattg aacaactgga cgggcaaatt gatgccttgc tttcagaaag agaaatattg
       61 atagaagaaa acaagcgatt gaaaaagaaa gtagcccaac caatgaaggg aggtggatag
      121 tatgaacaat agaacctttg atattttgaa atggatcgct atagtagtta tccccgcttt
      181 agcgactttt gtcggtcttg tcggaaaagg tgttaactgg cggtacacag atataacggt
      241 gatgattatt acaggttttg gagcatttct agggagtatt ttaggtgtat caaatcgaac
      301 gtataagaaa atttcatcag ataaatagga ggataga
//
LOCUS       DAFBVQ010000223          321 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.230, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000223 DAFBVQ010000000
VERSION     DAFBVQ010000223.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 321)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 321)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..321
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.230"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(69..321)
                     /locus_tag="LLC22_002961"
                     /pseudo
     CDS             complement(69..321)
                     /locus_tag="LLC22_002961"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002298938.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus and C-terminus; Derived by automated
                     computational analysis using gene prediction method:
                     Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="transposase"
BASE COUNT           79 a           78 c           51 g          113 t
ORIGIN      
        1 tccaaactcg taactcgagc ttggaacagc tttttatcta cttcgtttcg aatttttgaa
       61 caaaaaaata aaggctcctt gcctttccat agccaggtgg ctaatttctt taaattcatt
      121 gcagcaaaca ctagcatcgt atgcgtcgcg actttttcca agcctcgata cttggtccaa
      181 cgcatcccat gcttttcttt tgcatccgca aatattcgtt caatcgtttg tttccgtttt
      241 ttgtaaattg atttattcag atctgttagg cgaagatgtt ccacttcatc catcagatct
      301 ccccaaacat gtctcgtgat g
//
LOCUS       DAFBVQ010000224          308 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.231, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000224 DAFBVQ010000000
VERSION     DAFBVQ010000224.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 308)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 308)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..308
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.231"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>308
                     /locus_tag="LLC22_002962"
     CDS             <1..>308
                     /locus_tag="LLC22_002962"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335330.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="type VI secretion protein ImpB"
                     /protein_id="HBK5436139.1"
                     /translation="NGIDRTDIAIPPEPTKEKSYGNSQVLPRDYTRRNEIELVVKEMA
                     EQVAIRIRQHNCKTGCVHLHIGTSILETRPGFSHQMKIPITDNTKELQNYCLFLFDKY
                     "
BASE COUNT          115 a           54 c           65 g           74 t
ORIGIN      
        1 aatgggatcg atcgaacaga tatagcaatc ccaccagaac cgacaaagga aaaatcatat
       61 ggaaattcac aagtgttacc acgagattat actagaagaa atgaaatcga gctggtggta
      121 aaagaaatgg cggaacaagt agcgatacgc attaggcagc ataactgtaa aacaggttgt
      181 gtccatttac acattggcac gtcgatctta gaaacgagac cagggttttc acaccagatg
      241 aagatcccta tcacagataa tacaaaggaa ttgcagaatt attgtctttt cttgtttgat
      301 aagtatta
//
LOCUS       DAFBVQ010000225          305 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.232, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000225 DAFBVQ010000000
VERSION     DAFBVQ010000225.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 305)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 305)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..305
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.232"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="LLC22_002963"
     CDS             complement(<1..302)
                     /gene="tnpA"
                     /locus_tag="LLC22_002963"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287522.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS200/IS605-like element ISEfa4 family
                     transposase"
                     /protein_id="HBK5436140.1"
                     /translation="MELDTNNHSVFLLYYHLVLVTKYRRQVIDDEISDYAKTTFERIS
                     ESYHITLVEWNHDKDHVHIMFKAQPKTELTKFINAYKSASSRLIKRDFPRVKQFLW"
BASE COUNT           95 a           45 c           50 g          115 t
ORIGIN      
        1 ttccaaagaa attgtttgac tcttggaaag tcacgtttta tcaatcttga gctggcactt
       61 ttataggcat tgatgaattt tgtcaattct gttttaggtt gagctttgaa cataatatga
      121 acgtggtctt tatcatgatt ccactccact aaagtaatgt gatacgattc tgaaattctt
      181 tcaaaagtag ttttggcata atcagatatt tcatcatcaa tcacttgtct acgatatttc
      241 gttactaaaa caaggtggta ataaagaaga aatactgaat gattatttgt atctaattcc
      301 atgtt
//
LOCUS       DAFBVQ010000226          302 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.233, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000226 DAFBVQ010000000
VERSION     DAFBVQ010000226.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 302)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 302)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..302
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.233"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>302
                     /locus_tag="LLC22_002964"
     CDS             <1..>302
                     /locus_tag="LLC22_002964"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002312603.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="IS5/IS1182 family transposase"
                     /protein_id="HBK5436141.1"
                     /translation="EDIFAYILEQAVKAGFVTEDNLYLDSTHIKANANKHKFTKEMTH
                     DEAKAYQDELEDEINRQRIEAGKRPFTLDLEKEVKLKERKISKADPESGYYVKGER"
BASE COUNT          117 a           48 c           68 g           69 t
ORIGIN      
        1 tgaggatatt tttgcctata ttttagaaca agcagttaaa gcaggttttg taacagagga
       61 taatttgtat ctggattcta cccacatcaa agctaacgcc aataaacata agtttacgaa
      121 agaaatgacc catgatgaag cgaaagccta tcaggatgaa ttagaagatg agatcaatcg
      181 tcaacgaata gaggctggaa aacgcccttt tactttggac ttagaaaagg aagtgaagct
      241 gaaagaaaga aaaataagta aagctgatcc ggaaagcggc tactacgtca aaggcgaacg
      301 ag
//
LOCUS       DAFBVQ010000227          299 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.234, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000227 DAFBVQ010000000
VERSION     DAFBVQ010000227.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 299)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 299)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..299
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.234"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>299
                     /locus_tag="LLC22_002965"
     CDS             <1..>299
                     /locus_tag="LLC22_002965"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002360751.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS30 family transposase"
                     /protein_id="HBK5436142.1"
                     /translation="TIVGIHHKSAVITLVERLSKAIIALKPEGRKAVDIENSINEWLQ
                     SVPKNLFKSITFDCGKEFSNWKSISNTNDIDIYFADPGTPSQRGLNEHSNGLLRK"
BASE COUNT          102 a           63 c           54 g           80 t
ORIGIN      
        1 acgattgtcg gcatccacca taaaagtgcc gtcatcacac tcgttgagcg actttcaaaa
       61 gccattatcg ccttgaaacc agaaggccgt aaggcagttg atattgaaaa ttcgattaat
      121 gaatggcttc aatccgtacc caaaaatctt ttcaaatcaa ttacctttga ttgtggaaaa
      181 gaattctcta attggaaaag tattagtaat acgaatgata ttgatattta tttcgcagac
      241 ccaggaacgc cttcccaacg gggattaaat gaacattcaa acggactcct ccgaaaaga
//
LOCUS       DAFBVQ010000228          290 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.235, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000228 DAFBVQ010000000
VERSION     DAFBVQ010000228.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 290)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 290)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..290
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.235"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(<1..>290)
                     /locus_tag="LLC22_002966"
     CDS             complement(<1..>290)
                     /locus_tag="LLC22_002966"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436143.1"
                     /translation="KMISGQSKVLSVNGKYGAVILTKADLGLENAITELPYASETSDG
                     ILTAEMFQKIVNGEGGTYILPIATPEQLGGIKVGELLEVTEEGVLSATKQTD"
BASE COUNT           84 a           64 c           40 g          102 t
ORIGIN      
        1 aagtctgttt gcttagttgc agataaaaca ccttcttcag taacttctaa gagttcccca
       61 acttttatac ctcctaattg ttcaggagta gcaatcggca aaatatatgt tccaccttct
      121 ccatttacga tcttttgaaa catttcagca gtaagaatac catcgcttgt ctcgcttgca
      181 taaggtagtt cagtaattgc attctctaat cctaaatcag ctttcgttaa aatgactgca
      241 ccatatttac cattaaccga aagaactttt gattgtcctg atatcatttt
//
LOCUS       DAFBVQ010000229          266 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.236, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000229 DAFBVQ010000000
VERSION     DAFBVQ010000229.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 266)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 266)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..266
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.236"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            85..>266
                     /locus_tag="LLC22_002967"
     CDS             85..>266
                     /locus_tag="LLC22_002967"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002377182.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysM peptidoglycan-binding domain-containing
                     protein"
                     /protein_id="HBK5436144.1"
                     /translation="MTSLKTLLFGTTLAAGAAFFMGTTAHADEAYTVQSGDTLSTISQ
                     KYVGDNSLINAIAESNS"
BASE COUNT           84 a           55 c           43 g           84 t
ORIGIN      
        1 tacctatgaa atattttcac gtgttaaagt attcctcgtt gaacacaaca aataaaactt
       61 tttaacgaat aaaggagatt tttcatgaca tcacttaaaa ctttactttt tggaacaact
      121 ttggctgccg gcgctgcatt cttcatggga acgactgctc atgcggacga agcttatacc
      181 gttcaatcag gtgatactct atcaacgatt tctcaaaaat acgttggtga taactccttg
      241 atcaatgcca ttgcagaatc aaattc
//
LOCUS       DAFBVQ010000230          263 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.237, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000230 DAFBVQ010000000
VERSION     DAFBVQ010000230.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 263)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 263)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..263
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.237"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            51..>263
                     /locus_tag="LLC22_002968"
     CDS             51..>263
                     /locus_tag="LLC22_002968"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBK5436145.1"
                     /translation="MNHFKGKQFQQDVIIVAVGYYLRYNLSYREVQEILYDRGINVSH
                     TTIYRWVQEYGKLLYQIWKKKNKKSFY"
BASE COUNT           98 a           36 c           51 g           78 t
ORIGIN      
        1 tactatcaaa taaggtagaa taatagaaaa agatagcagg aggaatgacg atgaatcatt
       61 ttaaaggaaa gcaatttcag caggatgtga ttattgtagc cgtgggctac tatcttcgtt
      121 ataaccttag ctatcgtgaa gttcaagaaa tcttatatga tcgtggcatt aacgtttctc
      181 atacgacgat ttatcgttgg gtgcaagaat atggcaaact actctatcaa atttggaaaa
      241 agaaaaataa aaaatccttt tat
//
LOCUS       DAFBVQ010000231          260 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.238, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000231 DAFBVQ010000000
VERSION     DAFBVQ010000231.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 260)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 260)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..260
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.238"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..>260
                     /locus_tag="LLC22_002969"
     CDS             <1..>260
                     /locus_tag="LLC22_002969"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_064305258.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="IS6 family transposase"
                     /protein_id="HBK5436146.1"
                     /translation="TQAAYAFLKRLVKQFDEPKVVVTDKAPSITSAFKKLKEYGFYQG
                     TEHRTIKYLNNLIEQDHRPVKRRNKFYRSLRTASTTIKGMEA"
BASE COUNT           91 a           55 c           49 g           65 t
ORIGIN      
        1 acacaagcag cctatgcttt tcttaagcgg ttagtgaagc agtttgatga accgaaggtt
       61 gtagtcacag ataaagcccc ctctattaca agtgccttta agaaactaaa agaatacggc
      121 ttttatcaag ggacagaaca tcgtaccatt aaatacctga ataatttgat tgaacaagac
      181 catcgtccag taaagagacg caataaattc tatcgaagtt tacgcactgc ctctaccacg
      241 attaaaggca tggaagccat
//
LOCUS       DAFBVQ010000232          254 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.denovo.239, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000232 DAFBVQ010000000
VERSION     DAFBVQ010000232.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 254)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 254)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..254
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.denovo.239"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            46..>254
                     /locus_tag="LLC22_002970"
     CDS             46..>254
                     /locus_tag="LLC22_002970"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002359653.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436147.1"
                     /translation="MIDYNDRGRLKWAGFYLSDHTEEIDADNEQRTSQNLAKEQMTTE
                     EIAEVLNAAVIKNRSVSIQKEERNA"
BASE COUNT           96 a           36 c           62 g           60 t
ORIGIN      
        1 gcacacttgt tggtggtcat gcgggcggaa atgggggaat taaaaatgat tgattacaat
       61 gatcgtggac gtttaaagtg ggcagggttt tatttatctg atcatactga agaaattgat
      121 gccgacaatg aacaacgaac cagtcaaaat ttagcaaaag aacaaatgac gactgaagag
      181 attgcggaag tattgaacgc tgcagtcata aaaaatagat cagtatctat tcaaaaagaa
      241 gaacgaaacg ctga
//
LOCUS       DAFBVQ010000233        25666 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.guided.039, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000233 DAFBVQ010000000
VERSION     DAFBVQ010000233.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 25666)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 25666)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..25666
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.guided.039"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            196..2385
                     /locus_tag="LLC22_002971"
     CDS             196..2385
                     /locus_tag="LLC22_002971"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000470930.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AAA family ATPase"
                     /protein_id="HBK5436148.1"
                     /translation="MFISTLQIRNFRNYESEIFRFDNETNTIIGENDSGKTNALTALR
                     ILLDDSYYYSSKTLKESDFFHGIQNGWQGHWIIISATFEGISEEEFDNEICASISLNS
                     ESQTILEELISNADKGVGSISLFIRPNKAIRKQLFDISTELDSHQFNEFRNSIRLSDY
                     EFYYTSKSNLNFCINENYDKLVGRLNDNIASNPEEDDEALLGSRIDMSDIFKHISVVY
                     VDALRDVLREMKNNRNPVKRIMETIESKISSDNVESLKTIIQQLNETITSVPEIRKIG
                     ENINRQLNSIIGSVYSPNLLLSSTMSDDMGSLAKFLSMKPEQNIDLDLLGLGHLNMIY
                     LALKIVEFEACRSRELLNIMLIEEPEAHIHHHIQKTLFEGLNLQKNYTQILMTTHSVH
                     LAEVSEISRMNVLKSFNGKSIVMNPANNLNSFAKEKLKKNNLNLINAVERYLDVKRNG
                     LLFSKGVILVEGDAEEILIPQIVKKLFGINLDELGIGLINVGSTSFEYIASLFDDDRI
                     QRKCAIVTDLDEQAIPSEHRLYKSTAQEKGQARKEKLSSLFNENNWVNCFYANTTFEI
                     EFLDVNKENILTYVSPIIDDAFKDKKTITAYKEEIQSEQYLERNLAMLKLANHVGKGW
                     FAIELGEKIDFLIKIPKYILNAIAFACQEIVDLSIYKKILLHTIDLYEETTELSALSA
                     SLKTSDTADLNIAIISLLEYFGKDEDVVYLINQIENYTKILYAEVSK"
     gene            2382..4175
                     /locus_tag="LLC22_002972"
     CDS             2382..4175
                     /locus_tag="LLC22_002972"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000181735.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-dependent helicase"
                     /protein_id="HBK5436149.1"
                     /translation="MTNIFEKIVNDLNLEQKDVVESEDNLYVNACPGSGKTRVLTRKI
                     AYQAIKHDGSLKRIIAITYTNRAAEEIKERLSLLSIDDDINIWVGTIHQFCLEFIIYP
                     FKMNLSRVSKGFTIIDDYTQRAYVSQINNMLNLNLKTYELNKIDLSLSHDFKINEVQY
                     TQVSEMYHTMLEKNKEIDFDMILLVAYKILTVNSNVARNIASNIRAIYVDEFQDTREL
                     QYNVIAKLLQNNPQIQSMFVGDIDQAIYGSLDGIAKSVEELEMLTSHTFQSKTLHGCY
                     RSNQRLVDFYSNFQSCPYEIESRGNNKNDRGFISYDCKVTKEDLPNIIKNIIKEKIES
                     GIHEKDICVLAPQHYPLFSLGEYLKKELPYCNFDAINISPIKVNNHSLFFKLAILYFT
                     ESGEKVRRRKLIANDILIILKNEFGIEVKDYFIDLDLLQLINSVKRMYSGDDNGVDLY
                     KFVTKHIFVNLNIDEKNYPSIFKHYLFFINEVEDRIKNNSLSSSVSSFKKMFKSRDGI
                     TLTTAHKVKGNEYDTVIAINLLNGKIPHWNEIFNVSDKGISSARKLLYVICSRAKNNL
                     FLFSEVGYFTSKGDLLYPTQLLDKIEFDYNI"
     gene            4375..4689
                     /locus_tag="LLC22_002973"
     CDS             4375..4689
                     /locus_tag="LLC22_002973"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000421280.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5436150.1"
                     /translation="MELKYVIPNMEKTFGQLEYAGEGNIEQRRINGRPTILSRSYNLY
                     STIQRADDIVVILPSEAGEKHFESDEKVKLINPHITAEGYKIGNRGFTNYIMHADDMV
                     KA"
     gene            4710..5087
                     /locus_tag="LLC22_002974"
     CDS             4710..5087
                     /locus_tag="LLC22_002974"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001234189.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="YdcP family protein"
                     /protein_id="HBK5436151.1"
                     /translation="MRLAEGIVIEKDQTFGTLKFSALRREVRIQNEDGTVSEEIKERT
                     YDLKSKGQGRMIQVSIPASVPLKEFDYNAEVELINPVADTVATATFRGADVDWYVKAD
                     DLVLKGQTKPHQKYKKEASESEK"
     gene            5097..5870
                     /locus_tag="LLC22_002975"
     CDS             5097..5870
                     /locus_tag="LLC22_002975"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388713.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436152.1"
                     /translation="MTNTPLILKEIPKDEAISFIRQYHYSKILPRLCKYFLGIFSEEK
                     LLGVVELGWGTQPLQTIRKLFPDSSLQTTDYLEIGKMCFLPEMNQTNYFGSQALSALI
                     KWLKEHTDCHFLYTLADGIEGKCGYVYQASNFFYCGYFKTSVYRDKQSWEKIHPRSAR
                     LLLEENARFEQVEKKHWLSQAFCEYKGIEKINGRMFRYLYPLTKEAKKLLGHTLYRRH
                     YYPKEKNLRFEKRIAYQKYEAISQPTFDKQARIYNTQLF"
     gene            5892..7295
                     /locus_tag="LLC22_002976"
     CDS             5892..7295
                     /locus_tag="LLC22_002976"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001130245.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF87 domain-containing protein"
                     /protein_id="HBK5436153.1"
                     /translation="MPLLHDRGERIKANDKHLVYHFVLISLLVVFLVVLLPFHWRALQ
                     SVNWQAVQLDTFFYQLHTPYFWSSILTALFVCGLISWLYYHYRIDSIKQLEHRQKLAR
                     MILENHWYEAEETQSEGFFKDLPSKKTKQRIRHFPKIYYRMKDGLIHIHVEITLGKYQ
                     DQLLHLENKLETGLYCELVEKTLKDSYVEYVLLYDTIGNRIGIEDVVAQDGRVKLMES
                     VYWEFDSLPHMLIAGGTGSGKSYFILTLIESLLHTNAKLYILDPKNADLADLGAVMNN
                     VYYRKEDMLACINQFYEDMIDRSETMKQHPNYKTGENYAYLGLSANFLIFDEYVAMMD
                     MLGRESTTVIHKLKQIVMLGRQAGFFLILACQRPDAKYFSDGIRDNFNFRVALGRMSE
                     MGFGMMFGSDTQKQFFLKPIKGRGYVDTGKSVISEFYTPLVPKRYDFLGEIGKVIQKK
                     QSEPVPHEVKGTGSDLL"
     gene            7477..8661
                     /locus_tag="LLC22_002977"
     CDS             7477..8661
                     /locus_tag="LLC22_002977"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000426690.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="replication initiation factor domain-containing
                     protein"
                     /protein_id="HBK5436154.1"
                     /translation="MENEKIWIKELKEKRLAYGVSQNKLAVASHITRPYLSDIETGKA
                     VPTQQVKEDLLNALERFNPDNPLEMLFDYVRIRFPTNDVAQIIGEVLRLNMDYMLHED
                     FGYYSYPEHYRFGDIVVLVSHDVSKGVLLELKGKGCRQFENFLLAQHRSWYDFFQDCM
                     EHKGIFKRLDLAINDKTGILNIPDLAKKCKQEECISVFRSFKNYRSGELVHRDEKPYM
                     GNTLYIGSLKSEVYFCIYEKDYEQYVKNDVPLEDAEVKNRFEIRLKNDRATQAMKDLL
                     AHQQAEKTAFEIINRYIRFADKDDTKRRSDWKTNERWEWFIGKNRGALRLTTQPEPYS
                     FERTLNWLHHQVAPTLKIASILDVLNGTTIISTMIQEAKLTEKHEKLIEQQHLAMEDL
                     IT"
     gene            8658..8948
                     /locus_tag="LLC22_002978"
     CDS             8658..8948
                     /locus_tag="LLC22_002978"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000055367.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436155.1"
                     /translation="MSLLTKELKKLGFQCGIEFQAYIQNTGKYTSLIIEGKRQAGDTI
                     YTYDFYKVRFYNNYTNRVTVYGEHLTPFQLLRRVKSYIYYREKYLKERRTIT"
     gene            8945..9166
                     /locus_tag="LLC22_002979"
     CDS             8945..9166
                     /locus_tag="LLC22_002979"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464634.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436156.1"
                     /translation="MNFGQNLYNWFLDNAQSLVLLAIVVIGLFLGFKREFSKLIGFLI
                     IALIAVGLVFNAAGVKDVLLNLFNRIIGA"
     gene            9208..9987
                     /locus_tag="LLC22_002980"
     CDS             9208..9987
                     /locus_tag="LLC22_002980"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000678782.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="abortive infection family protein"
                     /protein_id="HBK5436157.1"
                     /translation="MKGFMNMFTNDQFKSLLIKTLERKSSSNYYEGGNEIVSKMKISE
                     VTLDETDDFTYYKGYKKGWNTLCTYLKIRVPFDDLDFFESHKDLITQTASSIYDKQGD
                     NVLVDTILVPLPENYEVINFSQLKISDVVSQAIEDAESFMSNGEYQRAFDRVHTAFHG
                     YLIEILKKYEITVPRDENLSKLYSRIQQLIEKEIQPTELADIVKTTIRSSNGMISSLN
                     EARNRHSLAHPNTNIIGKREAKLIIGISSTVTDYISGYLDK"
     gene            10054..10548
                     /locus_tag="LLC22_002981"
     CDS             10054..10548
                     /locus_tag="LLC22_002981"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000870467.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="antirestriction protein ArdA"
                     /protein_id="HBK5436158.1"
                     /translation="MKVYVANLGRYNEGELVGAWFTPPIDEEEMAERIGLNEDYEEYA
                     IHDFELPFDVDEYTPISEINRLCEAIQEIEGTPIYNELKEIQGMWFSSLEELLENKED
                     IHCYSDCDSMEDVARYYVEETGQLGEVPSNLQNYIDYQSLGRDMEIEGNYLVTSHGVF
                     EYCQ"
     gene            10604..11242
                     /locus_tag="LLC22_002982"
     CDS             10604..11242
                     /locus_tag="LLC22_002982"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000248477.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436159.1"
                     /translation="MVNVFENLKLLKLDMKDKGWVIDSFYFRYKQQNYIVLVKLFEKE
                     EKVPEYALLKLEFLKENDFSDMLAVYANSVKLYTDTKTIREYFGIEYSSNLGDVLFQF
                     SQTLARFIPTEVSEKKNEDQKEAMCFSLSQSDSEDPRKKYCFSVRRNPLKGNGELGKR
                     SPFNDNKTRLYRPSLYERLGSDTNLSFRYSMNPDDEETDEGIIAKWTKNKIE"
     gene            11314..11709
                     /locus_tag="LLC22_002983"
     CDS             11314..11709
                     /locus_tag="LLC22_002983"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:NP_464632.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5436160.1"
                     /translation="MKKIRSYTSIWSVEKVIYAINDLQLPFPITFTQMTWFIVSLFVV
                     ILFGSLPPLSLIDGALLKYLGIPIVLTGFMCQKTFDGKKPYGFLKSIITYALRPKVTY
                     AGKQIRLKKETMNESITIVRSEQLDGISD"
     gene            11693..14146
                     /locus_tag="LLC22_002984"
     CDS             11693..14146
                     /locus_tag="LLC22_002984"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000331166.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding protein"
                     /protein_id="HBK5436161.1"
                     /translation="MAYPIKYMEDNLVFNHDGEVFAYYELIPYNYSFLSSDEKIQVHD
                     NFCQLIAQNRDGKIHALQLATESSIRATQEQSKKEITGRLKEIAYEKIDEQTEALISM
                     IGDNQVDYRFFIGFKLYLNEQEVSVKNVGKEIQKAFAEFFHGVNHKLMGDFVSMPMAE
                     IERFSKMEQLLESKLSRRFQIRKLEKDDFGYIIEHLYGQTGVPFDDYDYHLPKRYEDK
                     KVLVKKYDILKPTRCLIEENQRYLRIEQEDTTTYVAYFTINSIVGELDFPNSEIFYYQ
                     QQQFTFPVDTSMNVEIVANKKALSTVRNKKKELKDLDSHAWESDNETSTNVVDALESV
                     DELESNLDQTKESMYKLSYVVRVSAKNLDELKQRCDEVKDFYDDLSIKLVRPFGDMLG
                     LHNEFIPSSKRYINDYIQYVTSDFLAGLGFGATQMIGENSGIYVGYNLDTGRNIYLQP
                     SLASQGIKGSVTNALASAFIGSLGGGKSFSNNMLVYYSVLFGGQATIVDPKAERGEWK
                     ETLPDIAHEINIVNLTSENDNKGLLDPYVILKLPKDSESLAIDILTFLTGISSRDSEK
                     FPVLRKAIRSVTQSKQRGLLLVIDELRKEDTPISNSIADHIESFVDYDFAHLLFSDGS
                     VTQSISLEKQLNIIQVADLVLPDSNSSFEEYTTMELLSVAMLIVISTFALDFIHSDRS
                     IFKIVDLDEAWSFLQVAQGKALSMRLVRAGRAMNAGVYFVTQNADDLLDEKMKNNIGL
                     KFAFRSTDLVEIKKTLEFFGVDKEDENNQKRLRELENGQCLVSDIYGRVGVMQFHPIF
                     EELLHAFDTRPPVRNEVEE"
     gene            14143..16170
                     /locus_tag="LLC22_002985"
     CDS             14143..16170
                     /locus_tag="LLC22_002985"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000192391.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436162.1"
                     /translation="MTQKQKKFLHYSWITLLCVGVILLLLGTLGNAVQATGLVDETID
                     TSNEYSKYGLNQYQLDYYVDNSWGWLPWNWSDGIGQSVMYGLYAITNFIWTISLYLSN
                     ATGYLVKEAYALDFISQTSQAIGENMQTIAGITPNGFSSSGFYVGFLLLFILIVGIYV
                     AYTGLVKRETTKVIRAVLNFVVVFILSASFIAYAPDYIAKINDFSKDVSTASLNIGTK
                     IVLPNTDSQGKDSVDMIRDSLFSVQVKQPWLLLQYGSTDVEALGEERVESLLSTSPDT
                     NNGEDRENVVIEEIEDHDNTYLTLPKTISRLGTVFFLFVFNIGISIFVFLLTGIMIFS
                     QVLFIIFAMFLPISFLLSMLPSFDGMGRHAITKLFNVIMTRAGITLIITVAFSISTML
                     YSLSASSPFFMIMFLQIVTFAGIYFKLGDLMSLFTLQSNDSQNMGRQVFRRPRQMMNR
                     QTRRFQRSMSKIFRGKAGSTKQKTMTTKQNQTNKANHTRQNERTTPKKETALSNVKKQ
                     QGGIGQRLGEKTAHVLDTKNRLVNKRKQAKQQIQATPTHVKYALHQGKENVTHNVTDF
                     KQSMADTKAQRKQQRMNQQEQKRKNIAQKRLELDKAKEKRRKENPSSPVQNNQQHVRK
                     RQQTVTPVLSQNTKRENHQRPLKKEQKQKTPPKQFNQRKLNKRTDKRGQQT"
     gene            16167..17189
                     /locus_tag="LLC22_002986"
     CDS             16167..17189
                     /locus_tag="LLC22_002986"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000768374.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="bifunctional lysozyme/C40 family peptidase"
                     /protein_id="HBK5436163.1"
                     /translation="MKLKITVICSVVFSLFFFLLLFLVIFFADDTDSGENNKDSSIPQ
                     GGVTVSPEVLAHRPLIEKYGKEYGIEDYVSYILAIMQVESGGTAEDVMQSSESLGLPP
                     NSLSTEESIKQGVKYFSELLTSAEQQGVDIDSVIQSYNYGGGFLNYVRSHGKKYTYEL
                     AEQFSKEKSGGQKADYPNPIAIPVNGGWRYNYGNQFYVQLVSQYLTDTSPTEFDGETV
                     QVIMDEALKYEGFPYVFGGASPTTSFDCSGLIQWVYDKAGISLPRVAQDQYDATQEIS
                     MEEAQAGDLIFFHSTYNAGTYVTHVAIYLEGNRFYHAGDPIGYGDLSSRYWQDHLIGA
                     RRVIHN"
     gene            17206..18135
                     /locus_tag="LLC22_002987"
     CDS             17206..18135
                     /locus_tag="LLC22_002987"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_017650613.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="conjugal transfer protein"
                     /protein_id="HBK5436164.1"
                     /translation="MIIKIERKEKKEKPKKSKKPSKQRKVPMIKVGTHKKLTFVLWVL
                     LIGSVGFGIYKNFTAIDTHTVRETEIIKQQIVDTNQVESFVKSFAKDYFSWQQSQEAI
                     DKRNEKLTHYLTEELQVLNEEMIRKDIPTSSSVNDIQVWQVSQVNENTFEVLFSVEQV
                     ITEDKDKETISSSFHVVVHIDESDNMVIIKNPTMSKKPQKSDYQPKQLESDHTVDTET
                     MDEITSFLETFFQLYPTATEKELTYYVSNHVLPMINKEYVFEELVNPIFTRKDNQVIV
                     NVAVKYLDQETKATQISQFELILEKQDNWKIVK"
     gene            18380..18496
                     /locus_tag="LLC22_002988"
     CDS             18380..18496
                     /locus_tag="LLC22_002988"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814923.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance determinant leader
                     peptide"
                     /protein_id="HBK5436165.1"
                     /translation="MILKYPENICMLCIPMVMHKNPSDKSIYHWDFYALLGF"
     gene            18512..20431
                     /gene="tet(M)"
                     /locus_tag="LLC22_002989"
     CDS             18512..20431
                     /gene="tet(M)"
                     /locus_tag="LLC22_002989"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011117014.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="tetracycline resistance ribosomal protection
                     protein Tet(M)"
                     /protein_id="HBK5436166.1"
                     /translation="MKIINIGVLAHVDAGKTTLTESLLYNSGAITELGSVDKGTTRTD
                     NTLLERQRGITIQTGITSFQWENTKVNIIDTPGHMDFLAEVYRSLSVLDGAILLISAK
                     DGVQAQTRILFHALRKMGIPTIFFINKIDQNGIDLSTVYQDIKEKLSAEIVIKQKVEL
                     YPNMCVTNFTESEQWDTVIEGNDDLLEKYMSGKSLEALELEQEESIRFQNCSLFPLYH
                     GSAKSNIGIDNLIEVITNKFYSSTHRGPSELCGNVFKIEYTKKRQRLAYIRLYSGVLH
                     LRDSVRVSEKEKIKVTEMYTSINGELCKIDRAYSGEIVILQNEFLKLNSVLGDTKLLP
                     QRKKIENPHPLLQTTVEPSKPEQREMLLDALLEISDSDPLLRYYVDSTTHEIILSFLG
                     KVQMEVISALLQEKYHVEIELKEPTVIYMERPLKNAEYTIHIEVPPNPFWASIGLSVS
                     PLPLGSGMQYESSVSLGYLNQSFQNAVMEGIRYGCEQGLYGWNVTDCKICFKYGLYYS
                     PVSTPADFRMLTPIVLEQAFRKAGTELLEPYLSFKVYAPQEYLSRAYNDAPKYCANIV
                     NTQLKNNEVIIIGEIPARCIQDYRNDLTFFTNGLSVCLAELKGYQVTTGEPVCQTRRL
                     NSRIDKVRYMFNKIT"
     gene            20529..20717
                     /locus_tag="LLC22_002990"
     CDS             20529..20717
                     /locus_tag="LLC22_002990"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011988843.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="cysteine-rich KTR domain-containing protein"
                     /protein_id="HBK5436167.1"
                     /translation="MINYKWILCPICGNKTRLRIRVDTILKNFPLYCPKCKNETLINV
                     QKMNIITIKEPDAKTQSR"
     gene            complement(20775..21128)
                     /locus_tag="LLC22_002991"
     CDS             complement(20775..21128)
                     /locus_tag="LLC22_002991"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001227349.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5436168.1"
                     /translation="MRKKEDKYDFRAVGLAIKEARMKRGLTREQVGTMIEIDPRYLTN
                     IENKGQHPSTQVLYDLVSLLHVSIDEFFLPTDNLIKSTRRLQVEKYMDSFTDKELSLM
                     EALAKGINEARNIEG"
     gene            21659..22081
                     /locus_tag="LLC22_002992"
     CDS             21659..22081
                     /locus_tag="LLC22_002992"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_006733729.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sigma-70 family RNA polymerase sigma factor"
                     /protein_id="HBK5436169.1"
                     /translation="MKPSSFQETIENQFDYICKQVIEDERKDYFKHLDRLSAKEVSFS
                     DIDNYLVNSFSTVDTYVTDFQLFKLFGLRINVESDLLSEALRHLSEKKRNIILLHYFM
                     DMSDVEIAELLNLNRSTVYRHRISGLAMIKEFMKECKE"
     gene            22078..22308
                     /locus_tag="LLC22_002993"
     CDS             22078..22308
                     /locus_tag="LLC22_002993"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002411750.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="helix-turn-helix domain-containing protein"
                     /protein_id="HBK5436170.1"
                     /translation="MKTAYPRVPFPLIVKATDGDVEAINQIVKHYRGYTSKRSLRRMT
                     DEYGNSHMVIDETLRGRMETKLISKILSFEIK"
     gene            22806..23006
                     /locus_tag="LLC22_002994"
     CDS             22806..23006
                     /locus_tag="LLC22_002994"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:YP_008475635.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF3173 domain-containing protein"
                     /protein_id="HBK5436171.1"
                     /translation="MITVTKKDLVELGYGTSFSADIIKKAKELMITKGHIYYQSRKLD
                     RVPREAVEEILGIRFSNENRSE"
     gene            23033..24226
                     /locus_tag="LLC22_002995"
     CDS             23033..24226
                     /locus_tag="LLC22_002995"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002388733.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="site-specific integrase"
                     /protein_id="HBK5436172.1"
                     /translation="MVKDPIKKAKNGTYYFRANLGYDSKGKKIQKYRSGFTTKKEARE
                     EYSKLLLMKPEELSENKDKMTFKHYIFEIFLPWYKTQVKLRTYENRLPTIKKHFSYFD
                     KMAVSDIEPIDVQNWQLKLSKKCKSSYVRAVQGLFSVAMDRAIVLGITTTNPSKIIGN
                     VKKQKSKIEFWTKEEFEKVISLIYKEDYYQHFLFISLWFLFMTGMRIGEATAIQWEDI
                     DFDSGVLTINKTLYYKNQSNYRFVEPKTKASVRHIVLDKCTLTYLSEWKEVQQNLIQT
                     DFVMSYNGIPTQKHTLSYAIERYAKLAGIHRIRIHGLRHSHASLLISMGENPLIIKDR
                     LGHEDIETTLGTYGHLYPNSNFEVANKLNGAISFKEAKQNYDTSPKNQFTVDYLRNKE
                     MKKVQ"
     gene            complement(24294..>25666)
                     /gene="guaA"
                     /locus_tag="LLC22_002996"
     CDS             complement(24294..>25666)
                     /gene="guaA"
                     /locus_tag="LLC22_002996"
                     /EC_number="6.3.5.2"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734496.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="glutamine-hydrolyzing GMP synthase"
                     /protein_id="HBK5436173.1"
                     /translation="VYDENAFGIDPEIFNLGIPVLGICYGMQLITYKLGGSVEPAKNR
                     EYGKALLEVTSDQAVLFKETPKQQTVWMSHGDLVTKVPEGFETVGTSKDCPIASIQDT
                     TRNFYGIQFHAEVRHSEYGIELLRHFAFDVCHCEGNWTMDNFIDMQVEKIREQVGDKK
                     VLLGLSGGVDSSVVGVLLQKAIGDQLTSIFVDHGLLRKGEAEQVMESLGGKFGLNIIK
                     VDARDRFLDKLKGVSDPEQKRKIIGNEFVYVFDDEATKLAGEEGVSFLAQGTLYTDVI
                     ESGTETAQTIKSHHNVGGLPEDMQFELIEPLNTLFKDEVRELGTQLGMPDSIVWRQPF
                     PGPGLGIRVLGEITEDKLEIVRESDAILREEIAAAGLDRDIWQYFTVLPGIRSVGVMG
                     DGRTYDYTVGIRAVTSIDGMTADFARIPWEVLQKISVRIVNEVAHVNRIVYDITSKPP
                     ATVEWE"
BASE COUNT         8807 a         4220 c         4900 g         7739 t
ORIGIN      
        1 aaggtttcca acaggccgaa ggcgagctcg aacaaatgct aagccaactg attgagaatt
       61 agaaacaatc tgcagtaggg aagaatcatt tacacaaaat tattgacgct cccttataat
      121 gagaactttt actaacataa tttatgataa acttactata taatcatatt aattaaatag
      181 ttaggagatc tgcttatgtt tatatctact cttcaaattc gaaattttag aaattatgaa
      241 tccgaaatct ttcgattcga taatgagaca aatactatta taggtgagaa tgattcaggg
      301 aaaaccaatg ctcttactgc attgagaatc ttattagatg atagttatta ctatagtagt
      361 aaaacactaa aagaatcaga tttttttcat ggaattcaaa atgggtggca agggcattgg
      421 attattatct ctgcgacatt tgaaggaatc agcgaagaag aatttgacaa tgagatttgt
      481 gcttccattt ctttaaattc tgaaagtcaa acaatcttag aagaattgat ttcaaatgca
      541 gataaaggtg taggtagtat ttctctattt attagaccta acaaagctat tagaaagcaa
      601 ttatttgata tttccactga attagactct catcaattta acgaatttag aaattctatt
      661 cgtctatccg actatgaatt ttactacaca tctaaatcaa atctaaattt ctgtatcaat
      721 gaaaattatg ataaattggt aggaagactc aatgacaata tagctagtaa tcctgaagaa
      781 gacgatgaag ctctgttggg ctcaagaatt gacatgtcag atattttcaa gcatatttcg
      841 gttgtttatg ttgacgctct tcgagatgtt cttagagaaa tgaaaaacaa tcgaaaccca
      901 gtcaaaagaa tcatggaaac aattgaatca aaaatatcat cagataatgt tgagtcatta
      961 aaaacaatta tacagcaatt aaatgagact attaccagtg ttcctgaaat taggaaaatt
     1021 ggcgaaaata ttaatcggca actaaatagc ataattggtt cagtgtattc tcctaatctt
     1081 cttctttcct caactatgtc agatgatatg ggttctttag caaaatttct ttcaatgaag
     1141 ccagaacaaa atatcgactt agacttacta gggttaggac atctaaatat gatttattta
     1201 gctttgaaaa tagtcgaatt tgaagcgtgt cgttcaagag aactacttaa tattatgttg
     1261 attgaagaac cagaagctca tattcatcat catattcaaa aaactctgtt cgaaggatta
     1321 aatcttcaaa aaaactatac tcagattctc atgaccacac attctgtaca tttagctgaa
     1381 gtgtctgaaa tatctcggat gaatgtatta aaatcgttta atggcaaatc tatcgttatg
     1441 aatccagcaa ataatctgaa ctcatttgct aaagaaaagt taaaaaagaa caatctaaat
     1501 ctaataaacg cagtagagag atatttagat gttaaaagaa atggattgct tttttctaaa
     1561 ggtgttatct tagttgaagg agatgctgaa gaaatactta ttcctcaaat agtaaaaaaa
     1621 ttatttggta taaacttaga cgaacttgga ataggtttga ttaatgttgg tagtacttcg
     1681 tttgaatata tcgctagctt gtttgacgat gatagaatac agagaaagtg tgctattgta
     1741 actgatttag atgaacaggc aatcccatca gaacatcgat tgtataaaag cactgcacaa
     1801 gagaaaggtc aagcaagaaa agaaaaatta tcctcccttt ttaatgaaaa caattgggtt
     1861 aattgttttt atgctaatac aacatttgaa attgagtttt tagatgtgaa taaagaaaat
     1921 attctaactt atgtcagtcc aattatagat gacgcattca aagataaaaa aacaataact
     1981 gcttataaag aagaaataca aagtgaacaa tatttagaaa gaaatttagc gatgttaaaa
     2041 ctagccaatc atgttggtaa ggggtggttt gcaattgagt taggtgaaaa aattgacttt
     2101 ttaatcaaaa ttcctaagta tattcttaat gctattgctt ttgcatgtca ggaaatagta
     2161 gatctctcaa tttataaaaa aattctactc catacaatcg acttgtacga ggaaactaca
     2221 gaattgtcag ctttatcagc tagtttaaaa acaagtgata cagctgattt gaatatagca
     2281 ataatttctt tattagagta ctttggtaaa gatgaggatg ttgtgtatct aatcaatcag
     2341 atagaaaatt acacaaaaat actttatgct gaggtttcaa aatgacaaat atcttcgaaa
     2401 aaatcgtaaa tgatttaaat ttagaacaaa aagatgttgt ggaaagtgaa gataaccttt
     2461 atgtaaatgc atgtcctggg agtgggaaaa caagggtact tacaaggaaa attgcttacc
     2521 aagcaattaa acacgatgga tcactaaaaa gaataattgc tatcacatac actaatagag
     2581 ctgctgaaga aattaaggaa cgcctaagtt tacttagtat agatgatgat attaatattt
     2641 gggtggggac aatacatcag ttttgtcttg aatttattat ttatcctttt aaaatgaatc
     2701 tctcaagagt atcaaaagga tttacaatta ttgatgatta tactcaaaga gcttacgtca
     2761 gccaaattaa taatatgctg aatttaaatc tcaaaacgta tgaactgaac aaaattgatt
     2821 tgtcactttc tcatgatttt aaaattaatg aagttcagta tactcaagtt tctgaaatgt
     2881 atcacactat gttggaaaaa aataaagaaa ttgattttga tatgatttta ctagtagcgt
     2941 ataaaatttt aactgtaaac agtaacgttg cacgtaatat tgctagtaat ataagggcga
     3001 tttatgtgga tgaatttcaa gatactagag aattacaata caatgtaata gctaaattac
     3061 ttcaaaacaa ccctcaaatt cagtcaatgt ttgttggaga tattgaccaa gcaatttatg
     3121 gatcattaga tggtatagct aaatcagttg aagaactaga aatgctaact agtcacactt
     3181 ttcaatcaaa gacgctacat ggctgttaca ggtctaatca gagattagta gacttctact
     3241 ctaattttca gagttgtcct tacgagattg aaagcagagg gaataataaa aacgaccgtg
     3301 gttttataag ttatgattgc aaagttacta aggaggattt acccaacata ataaaaaata
     3361 taataaagga aaagattgaa agcggcattc atgaaaaaga tatttgtgta cttgctcctc
     3421 aacactatcc tctgttttca ctgggtgagt atttaaagaa agaattaccg tattgcaatt
     3481 ttgatgctat aaatatatca ccaattaagg taaataatca tagtttattt ttcaagttag
     3541 caattttgta ctttactgaa tcaggtgaaa aggttcgaag aagaaagcta attgcaaacg
     3601 atattttaat tatattaaaa aatgaatttg gaatagaagt taaagattat tttattgact
     3661 tagatttatt acagctaata aacagtgtga aaagaatgta tagtggagac gacaacggtg
     3721 ttgatttata caaatttgtt accaaacata tatttgttaa tcttaatatt gacgagaaaa
     3781 attacccgtc tatttttaag cactatctat tttttattaa cgaagtagaa gatcggataa
     3841 aaaataattc attatctagt agtgtatcta gttttaagaa gatgtttaaa tctcgagatg
     3901 gtatcacact tactacagca cataaagtta aaggaaatga gtatgatact gttatcgcta
     3961 ttaatcttct aaacgggaaa attcctcatt ggaatgaaat ttttaatgtt tctgataaag
     4021 gaattagttc agcgagaaaa ctactatacg taatttgttc aagagcaaaa aataatttat
     4081 ttcttttctc agaggtgggt tattttacga gtaaaggaga cttgctttat cccactcaat
     4141 tattagataa aatagaattt gattataata tttaaaatac ctaggtagtc gttgttttaa
     4201 atatagtagg aatcggacgc tcagtacgga gcgtctattt ttttacccaa ttttgaaagg
     4261 aagtgaactt atgaaaataa aaaatcaaga atcaaaaggt cgctctcccc cctttaaaac
     4321 catcacacaa ataagattca ttcaaacata aaaacagaaa ggataggtaa aaatatggaa
     4381 cttaaatatg tcattcccaa tatggaaaaa acatttggac aattagaata tgctggtgaa
     4441 gggaacattg aacaacgtcg aataaatggc agaccaacca ttctctctcg tagttacaat
     4501 ttatactcaa cgattcaacg agcagatgat attgttgtca ttcttccctc cgaagctggc
     4561 gagaaacatt ttgaatccga cgaaaaagtc aaactcatca acccacatat taccgcagaa
     4621 ggttataaaa ttggcaatcg aggatttacc aattacatta tgcacgcaga cgatatggtg
     4681 aaagcataag aaaggaaagg tgaaaaaata tgagattagc agaaggtatt gtgattgaaa
     4741 aagaccagac atttggcaca ttgaaatttt ccgccttgcg tcgtgaggtt cgtatccaga
     4801 atgaagatgg tacggtttcc gaagaaatta aagaacgtac ctatgactta aaatcaaaag
     4861 gacaaggacg catgatacaa gtcagtatcc ccgcttctgt tcctttgaaa gaatttgact
     4921 acaacgcaga agtggaatta atcaatcctg tggcagatac cgtagcgacg gctacttttc
     4981 gaggggcaga cgttgattgg tacgtgaaag cagacgatct tgtattaaaa ggacagacaa
     5041 aacctcatca gaaatataaa aaagaagcgt ccgaaagtga aaaataggtg ttgcttatga
     5101 caaacacacc attgattttg aaagaaattc cgaaggatga agccatttct tttattcggc
     5161 aataccatta ttcaaagata ctccctagat tgtgtaaata ctttctaggg attttttcag
     5221 aagaaaaatt attaggcgtt gtggaattag gctggggtac gcaaccccta caaaccatac
     5281 gcaaactctt tcccgacagt tcccttcaaa ccacagatta tttagaaatt ggaaagatgt
     5341 gttttcttcc agaaatgaat caaaccaatt attttggcag tcaagctctt tcagctctaa
     5401 ttaagtggtt gaaagaacat acggactgtc attttttata tacactggca gatggaattg
     5461 agggaaaatg tggctatgtc tatcaagcgt ccaacttctt ttactgcggg tatttcaaga
     5521 caagtgtcta tcgtgataag cagtcatggg aaaagataca ccctcgaagt gctcgccttt
     5581 tattagagga aaatgctcgc tttgaacagg tagagaaaaa gcattggctt tcccaggcat
     5641 tttgcgaata caaagggatt gagaaaatca atggacgcat gtttcgctat ctctatccgt
     5701 tgacaaaaga agcgaaaaaa ctgttaggac acactctcta tcgacgtcat tattatccga
     5761 aagaaaaaaa tttacgcttt gaaaagcgaa tcgcttatca gaaatatgaa gccatttctc
     5821 aaccaacttt tgataaacag gctcgtatct acaatacaca attattttga taggtggaaa
     5881 ggaggatttt tatgccattg cttcatgaca gaggagagcg aatcaaagcc aacgataagc
     5941 acttggtcta tcattttgta ctaatttcat tgctggtagt ttttctagtc gtcctactcc
     6001 cttttcattg gagagcgtta caatcggtga actggcaagc agttcagtta gatacatttt
     6061 tctatcaact tcatacgcca tacttttgga gcagtattct cactgctctt tttgtatgcg
     6121 gacttatcag ctggctttat tatcactatc gtatagattc tataaaacag ttagagcacc
     6181 gtcaaaagtt agctcgtatg attttagaaa atcattggta tgaagccgaa gaaactcaat
     6241 cagagggatt ctttaaagat ttacccagca agaaaaccaa acaacgaatc cgccattttc
     6301 ctaaaatata ttatcgaatg aaagatggac taatccatat tcatgtagaa atcaccttag
     6361 ggaaatatca agatcagctt ttgcacctag aaaacaaact agaaacagga ttgtattgtg
     6421 aattagtgga aaaaacgttg aaagattctt atgtagagta tgtcctactt tatgatacta
     6481 ttggcaatcg aattggcatt gaagacgtgg tagctcaaga tggacgtgtc aaattgatgg
     6541 aatcggtcta ttgggagttc gattctctcc ctcacatgtt aattgctggg ggcactggta
     6601 gtggaaaatc ctattttatt ctcacattga ttgaatctct cctgcataca aatgcaaagc
     6661 tttatattct tgaccctaaa aatgctgatt tggcagactt aggggcggtc atgaataatg
     6721 tctattaccg taaagaagat atgttggcat gtatcaatca attttacgaa gatatgattg
     6781 atcgcagtga aaccatgaaa caacacccta actataaaac aggagaaaat tatgcttatc
     6841 ttggtttgtc tgccaatttt cttatttttg atgaatatgt ggcaatgatg gatatgctag
     6901 gtcgtgaaag taccaccgtt attcataaac tcaaacaaat tgtaatgtta ggacgacaag
     6961 caggcttctt tttaattctt gcctgtcaac gtccagacgc aaaatatttt agtgatggga
     7021 ttcgggacaa ctttaacttc cgtgtggctt tgggtcgtat gtctgaaatg ggctttggta
     7081 tgatgttcgg aagcgataca caaaaacaat ttttcttaaa acccatcaag ggaagaggtt
     7141 acgtggatac aggaaaaagt gtgattagtg agttttatac accccttgta ccaaaaaggt
     7201 acgatttctt aggagaaata ggaaaagtca ttcaaaaaaa gcaatctgag cctgtaccgc
     7261 acgaagtgaa aggtacaggt tcagacttgc tttgattggt gtggcgttag ccacgccaat
     7321 cctttagccc cctctatcta acaggggggc acaaatacaa ctgaaaacag gcaattctca
     7381 tcaaccaatg ttgatggtac aaaggattgc ggaaaatatg aaaggtgtaa actcaagggt
     7441 catagtttac atctttttta gattggaggt ttgcgaatgg aaaacgaaaa aatttggatt
     7501 aaggaattga aagaaaagcg actggcttat ggcgtttctc aaaataaact ggcggttgct
     7561 tctcatatta ccagacctta cctatcggat attgaaacag gcaaggcagt ccctactcaa
     7621 caggtgaaag aagatttact gaacgctttg gaacgcttca atcccgataa cccattggag
     7681 atgttattcg actatgtacg gattcgattc cctaccaatg atgtggctca aattatcggt
     7741 gaggttttac gtttgaatat ggattatatg ctacacgaag actttggcta ttattcttat
     7801 cccgaacact atcgtttcgg tgatattgtt gtcctagtct ctcatgatgt aagtaaaggt
     7861 gttttattag aactgaaagg aaaaggctgt cggcaatttg aaaactttct attggctcaa
     7921 catcggagct ggtatgattt ctttcaagat tgcatggaac ataaaggtat tttcaaacgc
     7981 ttggatttag ctatcaacga taaaacaggg attttgaata ttccagattt ggcaaagaaa
     8041 tgtaaacagg aagaatgcat ttccgtcttt cgaagcttta aaaattatcg cagtggtgaa
     8101 ttggttcacc gtgatgaaaa accatacatg ggaaacacac tttatattgg ctcattaaaa
     8161 agtgaagtct atttctgtat atatgagaaa gattatgagc aatacgtgaa aaatgatgtt
     8221 cccttagaag acgcagaagt aaagaatcgg tttgaaattc ggttaaaaaa tgaccgagcc
     8281 acccaagcca tgaaagattt attggcacat caacaggcgg aaaaaacagc ctttgaaatt
     8341 atcaatcgct atatccgctt tgcagataaa gacgacacta aacgtcggag tgattggaaa
     8401 actaatgaac gttgggaatg gtttatcggt aaaaatcgtg gagcattacg cctaaccaca
     8461 cagccagagc cttattcttt tgaacgaaca ttgaactggt tacatcatca agtcgcccct
     8521 acattaaaaa tcgcaagcat tttagatgtt ctcaacggta caaccattat ctccaccatg
     8581 attcaggaag ccaaactgac agaaaaacat gagaaattaa ttgaacaaca acatctagcc
     8641 atggaggatt tgattacatg agccttttaa caaaagaatt aaagaagtta gggtttcagt
     8701 gtggcattga gtttcaagcg tatatacaaa atacagggaa atatacgtct ctcattattg
     8761 agggaaaacg gcaagctggt gataccatct atacctatga tttttacaag gtgagatttt
     8821 ataataatta taccaatcga gtaaccgtct atggagagca tttaacccct tttcaattat
     8881 taaggcgtgt aaaaagctat atctattatc gagaaaaata tcttaaggaa aggaggacaa
     8941 tcacatgaat tttgggcaga atttgtacaa ctggttcttg gataatgcac agtcattggt
     9001 attgttagcg attgttgtca ttggactgtt tttaggtttt aaacgagaat tttcaaaact
     9061 cattggcttc ttgattattg ctctaatcgc cgtcggactt gtgttcaatg cagctggcgt
     9121 gaaagatgtg ttattaaact tatttaaccg aatcattggt gcttaacaga tatttttcat
     9181 gataaaatag gaagtatata ttttgttatg aaaggattta tgaatatgtt tacaaatgat
     9241 caatttaaat ctcttttaat taaaacatta gaaagaaaga gctcttcaaa ttattatgaa
     9301 ggaggtaacg agattgtttc taaaatgaaa atatcagagg taactttaga tgagactgac
     9361 gattttactt attataaagg atataaaaag ggctggaata cgctttgcac atatcttaaa
     9421 ataagagttc cttttgatga tttagacttt tttgaaagtc ataaagattt gattacccag
     9481 acagcaagct ccatatatga taaacaaggt gataatgtat tagtggatac tattttagta
     9541 ccacttccag agaattacga agtaattaac tttagtcagt tgaaaattag tgatgtggtt
     9601 tcacaagcta ttgaagacgc tgagtctttt atgagtaatg gtgaatatca acgtgccttt
     9661 gacagagttc acactgcttt tcatggatat ttaattgaaa tactaaaaaa atatgaaatt
     9721 acagttccta gagacgaaaa tctatctaaa ttatatagta ggatacaaca attaattgaa
     9781 aaagaaattc aacctactga acttgctgat atagtgaaga caacgataag gtcatcaaat
     9841 ggaatgatta gctctcttaa tgaagcaaga aataggcatt cacttgcaca ccctaataca
     9901 aatattattg gaaagagaga agcaaaacta ataataggta tttcaagtac agttacagat
     9961 tatattagcg gataccttga taagtagcgt cattaactga ttgctacttt ttttatgact
    10021 atttttataa aaaggatgtg ataagaattg gaaatgaaag tctatgtggc aaatttagga
    10081 cggtataatg aaggtgaatt agtcggagca tggtttactc caccaattga tgaggaagaa
    10141 atggcagaaa gaatcggttt aaatgaggac tacgaagaat atgcaataca tgattttgag
    10201 cttccttttg atgtggacga atacacgccg attagtgaaa tcaaccgtct atgtgaagcc
    10261 attcaagaaa tcgaaggtac acctatttat aatgaactca aagaaattca aggcatgtgg
    10321 tttagtagct tggaagaatt actggaaaac aaagaggata ttcattgtta tagtgattgt
    10381 gattcgatgg aagatgtcgc ccgttattac gtggaagaaa caggacagct tggtgaagtc
    10441 ccttccaatt tacaaaatta tattgactac caatctttgg gacgtgatat ggaaatagag
    10501 ggtaattacc tagttacctc tcatggggta tttgaatatt gtcagtaagt ttaacaatcc
    10561 gtgttataat taaattaata aatagcacgg agaggtataa attatggtaa atgtatttga
    10621 aaatcttaaa ctattaaaac tagacatgaa agataaaggc tgggtgatag attcctttta
    10681 ctttcgttac aaacagcaaa attatattgt acttgttaag ctatttgaaa aagaggaaaa
    10741 agttccagaa tatgctctgt taaaactaga atttttaaag gaaaacgatt tttcagatat
    10801 gctagctgtc tatgctaatt cggtaaaatt atatacagac acgaaaacaa taagagaata
    10861 ttttggtatc gaatacagta gtaacttggg agatgtttta tttcaattta gccaaactct
    10921 tgctcgattt attccgacag aagttagtga gaagaaaaat gaagaccaaa aagaagccat
    10981 gtgtttctca ttaagtcaaa gtgattcaga agatcccaga aaaaaatatt gtttttcagt
    11041 tagaagaaat cctttaaagg gaaatggtga gctgggaaaa cgaagtcctt ttaatgacaa
    11101 taaaacgaga ttgtatagac ccagcttata tgaacgatta gggtcagata ccaatttaag
    11161 tttcagatat tcaatgaatc cagatgatga agaaactgat gaaggtatta ttgcaaaatg
    11221 gacaaaaaat aaaattgaat agttaaagca ttgaaagagc aatcacctat tttgattgtt
    11281 ctttttctat ttttacggaa aggacgtgaa gacatgaaaa aaataagaag ttacaccagt
    11341 atttggtcag tagaaaaagt gatttatgcg attaatgatt tacaactccc tttcccaatt
    11401 acctttacgc aaatgacatg gtttatcgtt tctttgtttg tcgtcatact ctttggcagt
    11461 ttaccaccac tttctctgat tgacggagca ctactcaaat acttagggat tcccattgtt
    11521 ctcactgggt tcatgtgcca aaagaccttt gacggaaaga aaccctatgg atttctaaag
    11581 tctatcatta cctatgctct acgccctaaa gtaacctacg ctggcaaaca aatacgatta
    11641 aaaaaagaaa caatgaatga atcgattacg attgtaagga gtgaacaact agatggcata
    11701 tccgattaaa tatatggaag ataatctcgt atttaatcat gatggcgaag tattcgctta
    11761 ttatgaatta attccctata attacagttt tttaagttcc gatgaaaaaa ttcaagttca
    11821 tgataatttc tgtcaattga ttgcccaaaa tcgtgatggc aagattcatg ctctgcaact
    11881 agcaaccgaa tcaagtattc gagccacaca ggaacaatcg aaaaaagaaa tcactggacg
    11941 attaaaagag atagcttacg aaaaaataga tgaacagacc gaagcgttaa tttctatgat
    12001 tggtgacaat caagtagact atcgcttttt tattggtttt aaactctacc tcaatgaaca
    12061 ggaagtatcc gtaaaaaatg ttgggaaaga aattcaaaaa gcatttgcgg aattctttca
    12121 tggtgtgaat cacaaattaa tgggcgattt tgtttctatg cctatggcgg aaatcgaacg
    12181 cttttctaag atggaacagt tgttagaaag taaattatcc agacgctttc agattcgtaa
    12241 attggagaaa gatgattttg gttatattat tgaacatctt tacgggcaaa caggtgtccc
    12301 ttttgatgac tacgactacc atttaccgaa acgatacgaa gataaaaaag tgttggtaaa
    12361 gaaatacgat attctcaaac ccactcgctg tttaatcgaa gaaaatcaac gctatttacg
    12421 gattgaacag gaagatacca ctacttatgt ggcgtatttt acaattaata gtattgttgg
    12481 tgaattggat ttccctaata gtgaaatttt ttattaccag caacagcagt ttactttccc
    12541 cgttgatacc agtatgaatg ttgaaattgt cgccaataaa aaagccttat ctaccgttcg
    12601 caataaaaag aaagaactga aagatttaga tagccacgca tgggaaagcg acaacgaaac
    12661 cagtactaat gtggtggacg ctttagaatc tgtcgatgaa ttagaaagta atttagacca
    12721 aaccaaagaa tctatgtaca aactaagcta tgtggtacgg gtatcagcaa agaatttgga
    12781 cgagctgaaa caacgttgtg atgaagtaaa agatttttat gatgatctgt ctatcaaatt
    12841 agtacgacct tttggcgata tgctaggctt gcataatgaa tttattccct caagcaagcg
    12901 atatatcaat gactatattc aatatgtcac gtcggatttt ttggctggtc ttggtttcgg
    12961 tgctacacaa atgattggtg aaaattctgg tatttacgtc ggttacaatc tcgatacagg
    13021 cagaaatatt tatctccaac ctagccttgc aagtcaagga attaaaggct ctgtaacaaa
    13081 tgcattagcg tccgctttta ttggttcatt aggtggcgga aaatcattct ctaacaatat
    13141 gctggtctat tattcagtac tctttggcgg acaggcaacc attgttgacc caaaagctga
    13201 acgtggtgaa tggaaagaaa ccttacctga tattgcccat gaaatcaata ttgttaatct
    13261 cacgagtgag aacgacaata aagggttact tgacccttat gtgattttaa aactcccgaa
    13321 agattcagaa agccttgcca ttgatattct cacgttctta acaggtattt ccagccgaga
    13381 tagcgagaag tttcctgtcc tgcgtaaagc tattcggagt gtaactcaaa gcaaacaacg
    13441 agggttgtta ttggtgattg atgaattgcg aaaagaagat acgcccatca gcaatagtat
    13501 tgctgaccat atcgaaagct ttgtcgatta tgattttgcc catctgttat tcagtgatgg
    13561 cagtgtcacc caatccatta gcttggaaaa acaactcaat attattcaag tggcagattt
    13621 ggtcttaccc gattccaata gctcttttga agaatacact accatggaat tattaagtgt
    13681 ggcaatgctg attgtcatta gtacctttgc tttagacttt atccactctg accgttccat
    13741 ttttaaaatt gttgaccttg atgaggcttg gagtttttta caagtggcac aaggaaaagc
    13801 tctatctatg cgattggttc gagcaggacg tgccatgaat gcaggggtct atttcgttac
    13861 tcaaaacgcg gacgatttac tagatgaaaa gatgaagaat aatattggct tgaaatttgc
    13921 ctttcgttcc actgacctag tggaaatcaa aaagacctta gaattttttg gtgtggacaa
    13981 ggaagatgaa aacaatcaga aacgcttacg tgaattagaa aatggacaat gtttagtttc
    14041 agacatctat ggtcgtgtag gggttatgca gtttcacccg atttttgaag agttgcttca
    14101 tgcctttgat accagaccgc ctgtgcgaaa tgaggtggaa gaatgacaca aaaacaaaag
    14161 aaatttcttc actatagttg gataacgctc ctttgtgtgg gcgttatttt acttttatta
    14221 ggcacgctgg gcaatgcagt acaagcgaca ggcttagttg atgaaaccat tgatacaagc
    14281 aatgaatact ccaagtatgg tttgaatcaa tatcagcttg attattatgt ggacaatagc
    14341 tggggctggc ttccatggaa ttggagtgat ggcataggac aatcggtgat gtatggattg
    14401 tatgccatta ctaattttat ttggacaatt tctctttatc tatcgaacgc cacaggttat
    14461 ttggtgaaag aagcctatgc cttagatttc attagtcaaa catcccaagc aattggcgaa
    14521 aacatgcaga cgattgcagg cattacaccg aatggctttt ccagttcagg gttttatgtc
    14581 ggtttcctcc ttctttttat tctcattgtt ggaatctatg ttgcctatac aggattggtt
    14641 aagcgagaaa cgacgaaagt gatacgagct gttttaaact ttgtcgtggt gtttattcta
    14701 tcggcttcct ttattgcgta tgcacccgat tatattgcga aaatcaatga tttttccaaa
    14761 gatgtcagta ccgccagtct gaatattggg acaaaaattg ttcttcctaa cacggatagt
    14821 caagggaaag acagtgtgga catgatacgt gacagcttat tctctgttca agtaaagcaa
    14881 ccatggctat tgcttcaata tggctccact gatgtagaag cgttagggga agaacgtgtg
    14941 gaaagtttat tgtctaccag tccagataca aacaatggtg aagatagaga aaatgtagtg
    15001 attgaagaaa ttgaagatca tgacaatacc tatttaaccc taccgaagac gatttccaga
    15061 ttaggaacag tcttcttttt gtttgtattc aatattggta tctcgatttt tgttttcctt
    15121 ctaacaggaa tcatgatttt ttcgcaagtg ctatttatta ttttcgctat gtttttgcca
    15181 atcagtttcc tattaagtat gttgccgagt tttgatggca tgggcaggca tgccattacc
    15241 aagttattta atgtgattat gacaagggct ggtattacct tgattattac cgttgccttt
    15301 agtatttcca ctatgcttta ttcgctgtca gcaagttctc cctttttcat gattatgttt
    15361 ttacaaattg tgacctttgc agggatttat tttaaactgg gcgatttaat gagcctattc
    15421 actttacaaa gcaacgactc tcaaaacatg ggcagacaag tgtttcgcag acctcgtcaa
    15481 atgatgaatc gacaaaccag aagatttcaa cgcagtatga gtaagatttt tcgtggaaaa
    15541 gcagggtcaa cgaagcaaaa gacaatgaca acaaagcaga atcaaaccaa taaagctaac
    15601 catactcgtc aaaatgaacg gactacacca aagaaagaaa cagcactttc caatgtgaaa
    15661 aagcaacaag gcggtatcgg gcaacgatta ggtgaaaaga cagcccatgt attggacacg
    15721 aaaaatcgtc tagtcaataa aagaaagcag gcaaaacaac agatacaggc gacaccaacc
    15781 catgtcaaat atgcccttca tcaaggaaaa gagaatgtca ctcataatgt aacagacttt
    15841 aaacaatcta tggcagatac caaagctcaa cgcaaacaac agcgtatgaa ccagcaggag
    15901 caaaaacgaa agaacattgc tcaaaagcgt ttggagctgg ataaagcaaa agaaaaaaga
    15961 cgaaaagaaa acccatcatc tcctgttcag aataaccagc agcatgttcg caagcgtcag
    16021 caaaccgtca cgcctgtttt gtcacaaaac actaaacgtg aaaatcatca gcgaccattg
    16081 aaaaaagagc aaaaacaaaa gacaccaccg aagcaattca atcagaggaa gctaaataaa
    16141 agaacggata agcgaggaca acaaacatga agctaaaaat aacagtgatt tgtagtgtgg
    16201 tcttctctct cttctttttt ctcttattat tcctagtcat tttctttgca gatgatacgg
    16261 acagtggcga aaacaacaag gattcttcta ttccacaagg cggtgtgacc gtttcaccag
    16321 aagtgttggc acaccgtccg ttgattgaaa aatatggtaa ggaatatggg attgaagact
    16381 atgtttctta tatcttagcc attatgcaag tggaatcggg cggtacagca gaagatgtta
    16441 tgcaaagttc cgaatctttg ggtttaccgc ccaacagttt gagtaccgaa gagtccatca
    16501 aacaaggggt taaatatttc agtgaattat taaccagtgc agaacaacaa ggagtggata
    16561 tagattctgt tatccaatct tataattatg gcggtggctt tttaaattat gtgaggagtc
    16621 atgggaaaaa atatacctat gaattagccg aacagttttc taaagagaag tcgggtggtc
    16681 aaaaagcaga ctatcccaat cctatagcca tacctgtgaa tggtggttgg cgatataact
    16741 atggaaatca gttttatgtt cagttggttt cacaatacct aaccgacact tccccaacag
    16801 aatttgatgg tgaaaccgtg caagtcatta tggacgaagc cttgaaatac gaagggtttc
    16861 cctatgtctt tggaggggcg tcgcctacca cctcttttga ttgtagtggc ttaatacaat
    16921 gggtgtatga caaagctggc atttctctcc ctcgtgtcgc ccaagatcag tatgacgcta
    16981 cgcaagaaat ctctatggaa gaagcccaag caggcgacct tatcttcttt cattcaacct
    17041 ataatgcagg cacatatgtg actcatgtgg cgatatattt agagggaaat cgcttttatc
    17101 atgcaggcga cccaatcggt tatggcgact taagcagtcg ttattggcaa gaccatctga
    17161 ttggggctag acgtgttatt cataactaag aaaggaatga atcaaatgat tataaaaatc
    17221 gagcgaaaag aaaagaagga gaaaccaaag aaatctaaaa aaccgagcaa gcaaagaaaa
    17281 gttccgatga ttaaagttgg cacgcataag aaattaacct ttgttttatg ggttttattg
    17341 attggtagtg tcggatttgg aatctataaa aattttactg ccattgacac tcatactgtc
    17401 cgtgaaacag aaatcattaa acagcagatt gtcgatacca accaagtaga aagttttgtg
    17461 aaatcctttg cgaaagacta cttttcgtgg caacaatccc aagaagccat tgataaacga
    17521 aatgaaaaat tgacccatta tttgacggaa gaattgcagg tattaaatga agaaatgatt
    17581 cgtaaggata ttcctactag ttctagtgtg aacgatatac aggtgtggca ggtttctcaa
    17641 gtgaatgaga acacctttga ggtactgttt tctgttgaac aagttattac cgaagacaaa
    17701 gacaaggaaa ctatatcgtc tagctttcat gtggttgtcc atatagatga atcagataat
    17761 atggttatta tcaaaaatcc gacaatgagt aagaaacctc aaaaatcgga ctaccaaccc
    17821 aaacagctag aaagtgacca tacagtagat acagaaacga tggacgaaat cactagcttt
    17881 ttagaaacgt tcttccagct ctatcctacc gccacagaaa aagaattgac ttactatgta
    17941 agtaatcatg tgttacctat gattaacaag gaatatgttt tcgaggaatt ggtgaatcct
    18001 atctttacca gaaaagataa ccaagtaatc gtgaatgtcg ctgtgaaata tttagatcaa
    18061 gaaacaaagg caacccaaat ctcgcaattt gagttgatat tagaaaaaca agataattgg
    18121 aagattgtaa aataacaaat attggtacat gattacagat actttgtaat catgtactct
    18181 ttttgataaa aaattggaga ttcctttaca aatatgctct tacgtgctat tatttaagtg
    18241 actatttaaa aggagttaat aaatatgcgg caaggtattc ttaaataaac tgtcaatttg
    18301 atagcgggaa caaataatta gatgtccttt tttaggaggg cttagttttt tgtacccagt
    18361 ttaagaatac ctttatcatg tgattctaaa gtatccagag aatatctgta tgctttgtat
    18421 acctatggtt atgcataaaa atcccagtga taaaagtatt tatcactggg atttttatgc
    18481 ccttttgggt ttttgaatgg aggaaaatca catgaaaatt attaatattg gagttttagc
    18541 tcatgttgat gcaggaaaaa ctaccttaac agaaagctta ttatataaca gtggagcgat
    18601 tacagaatta ggaagcgtgg acaaaggtac aacgaggacg gataatacgc ttttagaacg
    18661 tcagagagga attacaattc agacaggaat aacctctttt cagtgggaaa atacgaaggt
    18721 gaacatcata gacacgccag gacatatgga tttcttagca gaagtatatc gttcattatc
    18781 agttttagat ggggcaattc tactgatttc tgcaaaagat ggcgtacaag cacaaactcg
    18841 tatattattt catgcactta ggaaaatggg gattcccaca atctttttta tcaataagat
    18901 tgaccaaaat ggaattgatt tatcaacggt ttatcaggat attaaagaga aactttctgc
    18961 cgaaattgta atcaaacaga aggtagaact gtatcctaat atgtgtgtga cgaactttac
    19021 cgaatctgaa caatgggata cggtaataga gggaaacgat gaccttttag agaaatatat
    19081 gtccggtaaa tcattagaag cattggaact cgaacaagag gaaagcataa gatttcagaa
    19141 ttgttctctg ttccctcttt atcatggaag tgcaaaaagt aatataggga ttgataacct
    19201 tatagaagtt attactaata aattttattc atcaacacat cgaggtccgt ctgaactttg
    19261 cggaaatgtt ttcaaaattg aatatacaaa aaaaagacaa cgtcttgcat atatacgcct
    19321 ttatagtgga gtactacatt tacgagattc ggttagagta tcagaaaaag aaaaaataaa
    19381 agttacagaa atgtatactt caataaatgg tgaattatgt aagattgata gagcttattc
    19441 tggagaaatt gttattttgc aaaatgagtt tttgaagtta aatagtgttc ttggagatac
    19501 aaaactattg ccacagagaa aaaagattga aaatccgcac cctctactac aaacaactgt
    19561 tgaaccgagt aaacctgaac agagagaaat gttgcttgat gcccttttgg aaatctcaga
    19621 tagtgatccg cttctacgat attacgtgga ttctacgaca catgaaatta tactttcttt
    19681 cttagggaaa gtacaaatgg aagtgattag tgcactgttg caagaaaagt atcatgtgga
    19741 gatagaacta aaagagccta cagtcattta tatggagaga ccgttaaaaa atgcagaata
    19801 taccattcac atcgaagtgc cgccaaatcc tttctgggct tccattggtt tatctgtatc
    19861 accgcttccg ttgggaagtg gaatgcagta tgagagctcg gtttctcttg gatacttaaa
    19921 tcaatcattt caaaatgcag ttatggaagg gatacgctat ggttgcgaac aaggattata
    19981 tggttggaat gtgacggatt gtaaaatctg ttttaagtac ggtttatact atagccctgt
    20041 tagtactcca gcagattttc ggatgcttac tcctattgta ctggagcaag cctttagaaa
    20101 agctggaaca gaattgttag agccatatct tagttttaaa gtttatgcac cacaggaata
    20161 tctttcacgg gcatataacg atgctcccaa atattgtgca aatatcgtaa atactcaact
    20221 gaaaaataat gaggtcatta ttattggaga aattcctgct cgatgtattc aagattatcg
    20281 caatgattta acttttttta caaatgggct tagtgtttgt ttagcagagc taaaaggata
    20341 tcaggttacc actggcgaac ctgtttgcca gacccgtcgt ctaaatagtc ggatagataa
    20401 agtaagatat atgttcaata aaataactta gtgcgtttta tgttgttata taaatatggt
    20461 ttcttattaa ataagatgaa atattcttta atatagattt gaattaaagt ggaaaggagg
    20521 agattgttat tataaactac aagtggatat tgtgtcctat ttgtggaaat aaaacaagac
    20581 tacgaatacg agtggatact atacttaaaa atttcccttt atactgcccc aaatgtaaga
    20641 acgaaacttt aattaatgtt caaaaaatga atataataac aatcaaagag ccagacgcca
    20701 agacgcagag ccgataattt gagaaatgaa actctcatct tatcggctct ttttgtttat
    20761 ctgaatttta ctgactagcc ttcaatattt cttgcttcat tgataccttt tgctagtgct
    20821 tccattaagg atagttcttt gtctgtaaag ctatccatgt atttttctac ctgtaacctt
    20881 cgagtgcttt taatcaaatt atctgtaggt aagaaaaatt catcaataga tacatggagt
    20941 aatgatacaa gatcatacag cacttgtgta cttgggtgtt gtcctttgtt ttctatattt
    21001 gttaaataac gtgggtcaat ttcaatcatt gttcccactt gttcacgagt gagaccccgt
    21061 ttcattcgag cctctttaat cgctaaacca acggctctaa aatcgtattt atcttctttt
    21121 ttacgcatac taaatcacct ctatacattt tactgttcct atataaccat aaacaggtat
    21181 agaaaaacat gttatatagt ttatgagttc ctatagaaca ctgtggaatt tattaatgcg
    21241 atgaatccaa tttcaaatag aaaggtcgct gattttattt acctatacaa ctttataaaa
    21301 tttagtcata ctcctagaaa gtagataaaa ttggcgactt aatggaggga aaagtcgcca
    21361 tgagaaagat aatctgtcat ctagttctct taattaagtt cttatcaaaa aaacttatcc
    21421 acctgtactg gatagatatg accatcaatg tggttttgca gattacatag atagaaaaat
    21481 caaagcatat gaacagagaa aacaatctgt ttatgtgctt ttttggtcac ttaataaata
    21541 tcttttagga tttctcttca tttatgcaac aaatccccct ttcgtgtcgg ggtttagtat
    21601 gaagggagat aaagaagcac atgccactcc ctttcacgac agaaaggggg tgaaaagcat
    21661 gaaaccatct tcttttcaag aaaccataga aaatcagttt gactatatct gcaaacaagt
    21721 tattgaagat gaacgaaaag attacttcaa acatctagac agactatcag caaaagaagt
    21781 ctcgttttct gatatagata actaccttgt caactctttt tctactgttg atacgtacgt
    21841 cactgatttc caactattta aattatttgg attaagaatc aatgttgaaa gtgatttatt
    21901 aagtgaagcc ctgcgtcatc tttcagagaa aaaacggaac attattttac ttcattactt
    21961 tatggatatg agtgatgtgg agattgcgga gttactaaat ttgaatcgtt cgactgttta
    22021 tcgtcatcga ataagtggac tagccatgat taaagaattc atgaaggagt gtaaagaatg
    22081 aaaacagctt atccaagggt tcccttcccc ctcattgtaa aggcgacaga tggcgacgtg
    22141 gaagcaatta atcagattgt taaacattat cgagggtata cctcaaaacg ttcattacgt
    22201 cgcatgacag acgaatatgg aaattctcat atggttattg atgaaaccct acgtggcaga
    22261 atggaaacga aactcatctc taagatttta tcgttcgaaa ttaaatagtc ccattttttc
    22321 gtggaagcgt gtcgaatcgt atccacgctt cccgatttgg gaggtttgtt attccatcaa
    22381 agcatattgt gtgttcagta ggttttgata ggctaacaag ccaaacgttc tttgacaacc
    22441 aaataaaggc aatcgaatac gtttcggtaa gaaaagagct gatgaactaa cacgccatga
    22501 cctacaaaat tagtgagcga ttcatgttag taattcgaaa gtaatcttta gcaggattgc
    22561 tgccatgact ttcttatcgt gataatgata ctcccgtata gccatagtcc gagcgttaga
    22621 agcgtcacag gcaatgggta cggctacatg agaaccatgc agaagtgaaa ttcctgtgag
    22681 ctttgctaga gctgttcgat tgctaagata ttcttctctt gtcagtgtat tattataaaa
    22741 ctatttgata taattatagg tgaatattgg agttttccta gcctataatt gggaaaggag
    22801 taataatgat aacggtcaca aaaaaggatt tagttgagct aggatatgga acttcttttt
    22861 cagcagacat cataaaaaaa gcaaaagaat tgatgattac aaaagggcat atctactatc
    22921 aatctcgaaa gctagataga gtccctcgtg aagctgttga agaaattcta ggaattcggt
    22981 tttcaaatga aaacaggtct gagtagtttt tgcacagtaa ggagtaaaaa ctatggttaa
    23041 agacccaata aaaaaagcaa agaatggaac ctattatttt cgtgcaaatc taggttatga
    23101 ttctaaaggg aaaaaaattc aaaaatatcg tagtggattc actactaaaa aagaagcaag
    23161 agaagaatat tcgaaactgc tattgatgaa accagaagaa ttaagtgaga ataaggataa
    23221 aatgacgttt aaacattata tctttgaaat tttccttcca tggtataaga cacaggtaaa
    23281 gctcagaaca tatgaaaatc gcttaccaac tattaagaag catttctctt attttgataa
    23341 aatggctgtt tccgatattg agcctattga tgtgcaaaat tggcaactaa aattatcaaa
    23401 gaagtgtaag tcttcttatg taagagctgt tcaaggacta ttttcagttg ctatggatcg
    23461 agcaattgtc cttgggataa ccaccacaaa tccatctaag attattggca atgtgaaaaa
    23521 gcaaaagtct aaaattgaat tttggacaaa agaagaattt gaaaaagtaa tctctctaat
    23581 ttacaaagaa gattactatc aacacttttt atttatctct ctgtggtttt tatttatgac
    23641 tggaatgcga attggtgaag ctactgccat tcaatgggaa gatattgatt ttgactcagg
    23701 agtactaacc atcaacaaaa cactctatta caagaatcaa tcgaattata gatttgttga
    23761 accaaaaaca aaggcgagcg ttcgtcatat tgtattagat aaatgcacat taacttattt
    23821 atccgaatgg aaggaagtac aacaaaatct aattcagaca gactttgtaa tgagctataa
    23881 cggtattcct acccaaaaac atacactatc atatgctatt gaacgctatg ctaagctggc
    23941 tggtatccat cgaatcagaa tccatgggtt acggcattct catgcttcct tgttaatcag
    24001 tatgggagaa aatccactta tcattaaaga tcgtctagga cacgaagata ttgagacgac
    24061 tttaggaacg tatggacatc tttatcctaa cagtaatttc gaggtagcta acaaattaaa
    24121 tggagccatt tcctttaaag aagcaaaaca aaattatgat acttcaccaa agaatcaatt
    24181 tactgtagac tacttgcgaa acaaagaaat gaaaaaagtg caataaaagt gcagtaaaaa
    24241 gataagaaga gccagaaacc cttggtataa gaggatttct agctctccta caactattcc
    24301 cactccactg ttgctggtgg tttagaagtg atgtcataca cgatacggtt gacgtgggct
    24361 acttcgttta cgatacgtac agagattttt tgcaagactt cccatgggat acgggcaaag
    24421 tcagcggtca ttccgtcgat tgaagttaca gcacggatac cgactgtgta gtcgtaagta
    24481 cgtccgtcac ccataacacc gacagagcgg atccctggaa gaacagtgaa atattgccag
    24541 atatcacggt caagtccagc agctgcgatt tcttcacgca agatagcatc agattcgcgt
    24601 acgatttcta gcttgtcttc agtgatttcg ccaagaacac gaataccaag accaggacca
    24661 gggaatggct gacgccaaac gattgaatca ggcatgccta actgagtccc taattcacgg
    24721 acttcgtctt tgaataatgt gtttaatggt tcgatcaatt caaattgcat atcttctggc
    24781 agtccaccta cattatggtg agatttgatc gtctgtgctg tttctgtacc agattcgata
    24841 acgtcagtat acaacgttcc ttgtgctagg aaagagacgc cttcttcacc agcaagtttt
    24901 gttgcttcgt catcaaaaac atatacgaat tcattcccaa tgattttacg tttttgttct
    24961 gggtcagata cacctttcaa cttgtctaag aagcgatctc ttgcatcgac tttgatgatg
    25021 ttcaagccga attttccgcc tagactttcc attacttgtt ccgcttcgcc tttgcgtagc
    25081 agaccgtggt caacaaagat agatgtcaat tggtcaccga tcgctttttg taaaagaacc
    25141 ccaacgacac tagaatcaac gccacctgaa agaccaagca agactttttt gtcaccaact
    25201 tgttcacgga ttttttctac ttgcatatcg ataaagttat ccattgtcca gttaccttca
    25261 cagtgacaaa catcaaaggc aaagtggcgc agcaattcga ttccgtattc ggaatgacgt
    25321 acttctgcat ggaattggat accataaaaa ttacgtgttg tgtcttggat agaagcaatc
    25381 ggacaatctt tgcttgttcc gactgtttca aagccttcag gaactttagt taccaagtca
    25441 ccatggctca tccatactgt ttgttgtttt ggtgtttctt taaacaagac agcttgatcg
    25501 cttgttactt ctaacaaggc tttcccatat tcgcggtttt tagcaggctc tacggaaccg
    25561 ccaagtttgt acgtgatcaa ttgcatacca tagcaaatcc ctaatacagg aatacctaaa
    25621 ttgaagatct caggatcgat cccaaatgca ttctcatcat atacac
//
LOCUS       DAFBVQ010000234        20985 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.guided.048, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000234 DAFBVQ010000000
VERSION     DAFBVQ010000234.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 20985)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 20985)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..20985
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.guided.048"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            complement(134..577)
                     /locus_tag="LLC22_002997"
     CDS             complement(134..577)
                     /locus_tag="LLC22_002997"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF305 domain-containing protein"
                     /protein_id="HBK5436174.1"
                     /translation="MKKYWKFLLMIGVSTVVMFGMMYLNVYALDHIFFSRTRVFMALM
                     MGAVMAVIMLLFMWKMYENKKINVMILAASLLVFAGSLFMVRSQTTVNDTAWMKAMIP
                     HHSIAILASKRADLKDPEVKKLAEEIIQAQEEEIDKMKKMIKEME"
     gene            complement(795..2135)
                     /locus_tag="LLC22_002998"
     CDS             complement(795..2135)
                     /locus_tag="LLC22_002998"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002331624.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5436175.1"
                     /translation="MEDKKLKKQLSSRHITMLALGGAIGAGLFKGSGEAIGIAGPSVL
                     IAFLIGGLILYIVMKGLGKIVLSGGDTHHGLSGLIRPYLGAHSADFTDWVYWSMWIIN
                     IIAEAVAAASFLQLWFPHIPAWVFVFMLAVLTTIINLYSVRLFAETEYWLAFAKISVI
                     ILLIIFATYLVGQQMLGTGVFPTLQQLTDHGGFTPHGMKGIISSLLVVIYSYGGSELI
                     AITVSEADDPKRAIPKAIKGVMGRIISFYIIPLFLLLILFPWNTLAGTNVSPFVMVFE
                     KMNIPFAADIVNFVIVLALFSSINSGVYASSRILFFRLKDRKGSSRKLAVLNKHQVPQ
                     RAVLFCTSVLYLGVALSYFVGDKLFGYLAGSLSYTVLLIWIIISAASFVLALRKGTLW
                     DKGISFFALAVLGLIFLGILFTNSIGVTVLTGLLYLFIYFSYQKKNDAFVLTNE"
     gene            2404..3300
                     /locus_tag="LLC22_002999"
     CDS             2404..3300
                     /locus_tag="LLC22_002999"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002323722.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="oligosaccharide biosynthesis protein Alg14"
                     /protein_id="HBK5436176.1"
                     /translation="MNKNDVLLVAKNKSLYFLPSIRSLDVWSGKDLLQSEFIKSARQQ
                     LANYQLIVFLDYGFDMEMARRVRPFTNAKIVLFFWNHFKAEHEAMLKQAQDEPAIDEI
                     YHFDFLEAKELGLKHNSSFYSKHMNFSSSEPKTDLFFGATNNGRKERAESYKQEFIKR
                     DVTTNYFILPHRGNEQPGYLTYEEYLKKTGESRGILELLREGQQGVTLRTFESMYFQK
                     KLVTDNQAIAHYHFYRPENIFLLRERDLDELPEFLHTPFKPILSELLEFYDAENWAKR
                     FITNDSTIYEQYEYDLSSVENK"
     gene            complement(3450..4391)
                     /locus_tag="LLC22_003000"
     CDS             complement(3450..4391)
                     /locus_tag="LLC22_003000"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376203.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="2-dehydropantoate 2-reductase"
                     /protein_id="HBK5436177.1"
                     /translation="MKIAIAGAGAMGSRIGLMLHQSGNEVLLIDRWPAHIEAIRTNGL
                     IADFNGKEVVAKLPIYSPEEIIESNEHVDLIVALTKANQLDDMFCSIQSIITDNTYVL
                     CLLNGLGHEDVLEKYVPKKNILFGITMWTAGLAGPGKVTLLGDGEIELENLEPEGEAF
                     TKKVVEVFQEANLNPIYSHNVRYSIWRKACVNGTLNGLCTILDCNIAELGAQKAAESM
                     VRTIVSEFASIAAKEGIILDQEEVYQHIASTYDPDNIGLHYPSMYQDLIKNHRLTEID
                     YINGAIWRKGQKYDIATPYCAFLTQLVHAKEGILGAE"
     gene            4517..5638
                     /locus_tag="LLC22_003001"
     CDS             4517..5638
                     /locus_tag="LLC22_003001"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306095.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycerate kinase"
                     /protein_id="HBK5436178.1"
                     /translation="MDILAAIDSFKGSASSFELNQAVLNGWEDRKGRKINVPIADGGE
                     NTAEAIYYALRGTWRTIDGMDLLFRQRKISYLLTTWQGKNTAVIESAQALGLDLLDKP
                     TDQTIRLASSYALGELIKDALLQEVEQIIVTLGGSGCSDGGLGLLQSLGASLEGYTEG
                     NPLLSTKKLHFDRRNVLVSKVKLIIAADVTNPYTGQQGAAWQFGRQKGGIDTTLAFLD
                     KQAGKIAQQIKDFWEVDLDDIPGSGAAGGIGGALFLLGAKMVSGFDLVSQITGLEKKI
                     EQADVIITGEGRIDQQTIHGKVPYGVAVLAKKYRKPIIAICGSRDQELEGLSDFLPIV
                     LSIHLGPIGLEEAMEHRQTLEKTKILGQTLSRFFTILPK"
     gene            5896..7398
                     /gene="eat(A)"
                     /locus_tag="LLC22_003002"
     CDS             5896..7398
                     /gene="eat(A)"
                     /locus_tag="LLC22_003002"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296175.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Eat(A)"
                     /protein_id="HBK5436179.1"
                     /translation="MSKIEIKNLTFGYDSQGTLLFEQANLNFDTQWKLGLIGRNGRGK
                     TTLLNILQNKLPYQGQVIHQQEFAYFPQQTKDKERLTYYVLNDITDFEIWEIERELQL
                     MQTDPEILWREFSTLSGGEKTKVLLALLFVDDTHFPLIDEPTNHLDISGRKQVAAYLK
                     KKKQGFIVVSHDRGFIDEVVDHVLAIEKSQLELYQGNFSIYEEQKKLRDEFEMAQNEK
                     LKKEVSRLKKTAAEKAEWSRSREGDKTKKQVGFIDTESRRVNKGAVGADAARTMKRSK
                     AIVNRMETQISEKEKLLKDIEYIDSLTMNSQASHHKRLLSVEDLQLGYENLLFEPIHF
                     TIEPHQRVAISGPNGAGKSSIIHYLLGAFNGKVIGEKYQPKHLSISYASQNYEDNRGT
                     LAEFAEKNQVDYQAFLNNLRKLGMERDVFHNKIEQMSMGQRKKVELAKSLSQPAELYT
                     WDEPLNYLDVFNQEQLEQLILNVKPAMLLVEHDQTFLDKVSTEIISLERI"
     gene            7426..7992
                     /locus_tag="LLC22_003003"
     CDS             7426..7992
                     /locus_tag="LLC22_003003"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373999.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="histidine phosphatase family protein"
                     /protein_id="HBK5436180.1"
                     /translation="MVKGNFANEGENHMLYVTRHGETTWNAQGLVCGRADVPLTEKGQ
                     MQAQKLAEKVVDLPVPITKIIHSPLQRARDTAQAVADRLSLPLTVDERLVEMDFGDYD
                     GLPSKDENFQKARLAFAVRFPNGESVLDVYARIVPLLKECIEDEENVYLLVCHNALIR
                     VINAYFHPMPNEGFFTFMVDNTELVSYE"
     gene            8203..9264
                     /locus_tag="LLC22_003004"
     CDS             8203..9264
                     /locus_tag="LLC22_003004"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368660.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF871 domain-containing protein"
                     /protein_id="HBK5436181.1"
                     /translation="MFGFSIFMNDSLSEEKKQYIRQMASNGFVGIFTSMHIPEDDVSA
                     YQKRLIELGSEAKKNKLELMVDISGEALERAGFSLEDLTPLKAIGVTGLRMDYHISNQ
                     QIADWSHQLKISLNASTITPKDIDELKEAEADFSQIEAWHNYYPRPETGLDKEWYQKK
                     NQWLKIQGLLVQGFVPGDTELRGPLYQGLPTLEEHRGIHPLAGALDLLASNTDIVYIG
                     DAGLSENVQEQFASFQKEQTVLLHTEPVDEEFYEYILGKHTNRQDDARDVIRSVDARF
                     REIPPIPARNTATRMKGSITLDNEKYLRYMGEIQLTKYDLPADEKVNVVAKVIKEELP
                     LINQIKAGMNYQFIRKEGR"
     gene            9267..10163
                     /gene="murQ"
                     /locus_tag="LLC22_003005"
     CDS             9267..10163
                     /gene="murQ"
                     /locus_tag="LLC22_003005"
                     /EC_number="4.2.1.126"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002368658.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="N-acetylmuramic acid 6-phosphate etherase"
                     /protein_id="HBK5436182.1"
                     /translation="MSKINLENLTTERRNQETFGLDEMSISQAVQLMNKEDQKVAAAV
                     EKELTSIEPVIANTIESFKKGGRLIYMGAGTSGRLGVLDAAECVPTFGVEPEMVIGLI
                     AGGEEAMTVAVEGAEDSYELGQEDLIKLNLTKNDIVIGIAASGRTPYVIGGLDYAKSI
                     GAVTGTISCNKQAEISKHADFPIEVDAGPEFLTGSTRLKSGTAQKLILNMISTISMIG
                     IGKVFNNLMVDVKPTNEKLIERSKRIIMQATEADYETAEKYFEEADQNVKLAIVMILT
                     NSDKEEAQAKLAEANGFVKGTL"
     gene            10177..12159
                     /locus_tag="LLC22_003006"
     CDS             10177..12159
                     /locus_tag="LLC22_003006"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002334912.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS glucose transporter subunit IIA"
                     /protein_id="HBK5436183.1"
                     /translation="MAKNELTLEELAKQIYKGAGGMGNVESIVHCMTRVRMKIINDDL
                     VNVSELKAIPGVLGVVEDEQLQVIIGPGKVNKVAQQMVDLAGVKLGEKLSSVSTATAN
                     SSASGKDRVNERAQEMKAAQKSKQKPSKIKSVLKDISNIFVPMIPAFVGTGIVAGIAA
                     VLANLVTAGTLDAATWQQYIDVMNILKNGMFSYLVIYTGINAAQVFGATPTLGGVIGA
                     VVMLTGMNPEAPLKNLFTGEALAAGQGGILGVIFAVWLLSIVEKKLHKVVPDAVDIIV
                     TPTLSLIAIGLIEIFFIMPLAGFISDGMVGGINWVLGVGGAFAGFVLGTLFLPMVMFG
                     LHQILTPIHVQMIDETGRTLLLPILAMAGAGQVGAALALWIRCKKDKELTEMIKGALP
                     VGILGIGEPLIYGVTLPLGRPFITACIGGGIGGAVIGMIGNVGAIAIGPSGAALIPLI
                     SDGKWLGYILGLLAAYAGGFVATFFFGIPKDRLEKEELATETATVNEVPEKVVPQTSA
                     ESVTILSSVADGTVVSLDKASDPVFAQKMMGEGYFVEPENGHIYSPVTGVVSSVFPTK
                     HAIGITTPNGLEILLHMGINTVDLGGTPFDVKVTEGQQVTPDTLVAEADLEAIKAAGK
                     ETSMIVLVTNMDRVKNFVLEKTGKAKAKAPVMDVKA"
     gene            complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="LLC22_003007"
     CDS             complement(12224..12670)
                     /gene="nrdI"
                     /locus_tag="LLC22_003007"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002299965.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class Ib ribonucleoside-diphosphate reductase
                     assembly flavoprotein NrdI"
                     /protein_id="HBK5436184.1"
                     /translation="MNILYISISGNTRAFAKHLAEYAEKMHAEDPVNPEVTLKEIHEN
                     SDFTKETEPFFTFVPTYLDGGNGLDNGDTEILTETMREYLEHEDNHKLCLGVVGSGNK
                     NFNNQYCLTAKQYAQTFGFPFLADYELRGTPSDVTRIYQILAENNK"
     gene            12881..14305
                     /locus_tag="LLC22_003008"
     CDS             12881..14305
                     /locus_tag="LLC22_003008"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016853071.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="amino acid permease"
                     /protein_id="HBK5436185.1"
                     /translation="MDTEQQKKGIGLIPLAALVIGSAIGGGVFGIMTDISGSAGGPAI
                     FSWVLVGTAMLMLSLSINNINKKRPDLKGGIFSYAEEGFGRFAGFISGWGYWLTCWLG
                     NVAFATLLMSALGYFFPVFEGGQNLASIVMSTVFLWGYAWLVNRGVENASFVNAIVTF
                     CKLVPLFLFIVVAISTFSIQQFIDNFSSDIILNANGQPIPFSSQVLSCIMVMLWVFVG
                     IEGASVVGSRAKKQSDVGKATILGIFGLIIIYVLVSMLPYGTMTMNQLQTIKAQPAMG
                     YVFEMMVGKWGAVVINGGLIISLVGVWLSWTILPIETMGNMAEDGLLPKAWGKLNKNG
                     APTYAIVLTTLCTNVFLLSLLFTDSAYNFAYTLGTAAIFFTWLFLGLYQMKLSYQRKE
                     WVQFLVGLLASAFQVWAMLVVAFNEVMLVLVLFLPGIYFYLKARKEQNEPVQHIHLDK
                     ILLIGVTMVGVIAMVLFATGMLHV"
     gene            complement(14486..15259)
                     /locus_tag="LLC22_003009"
     CDS             complement(14486..15259)
                     /locus_tag="LLC22_003009"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373993.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ABC transporter permease subunit"
                     /protein_id="HBK5436186.1"
                     /translation="MTLLVKQELFKLIKKKSTAVLSVLLVVLLIGTALLAKKYTTIID
                     PVEMTAQLFSATSWIVFIMIAAASTIISMEAQYGTLKNLLYRKYSRGEILVSKWITLV
                     IYSVYLYLLAIIVTVLMKLILFPSISFTEKVSTGQTLIQSLFTYTLGSYIGLWLILSL
                     VLMIACFINSSGASISAGIVFYFASSIISGILIALIQKWEWIKWNPISMLNLQNQIGN
                     EEIMKQLTHLSTNQMLFGNLAYIVLFLALGYLVFKRKNV"
     gene            complement(15256..16161)
                     /locus_tag="LLC22_003010"
     CDS             complement(15256..16161)
                     /locus_tag="LLC22_003010"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002316458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ATP-binding cassette domain-containing protein"
                     /protein_id="HBK5436187.1"
                     /translation="MKSLSVQELSKNFGHKQALSDVSFSLSPGKIVGLVGPNGAGKTT
                     IMKAILGLIHYSDGTICIGENEISPSSHKGLEQVGALIEYPGIYPFLTGYDHLKLFSE
                     TNDVSAIDTIVNQLKMEKYIHKKAKSYSLGMKQKLGIALALLNHPSIVILDEPMNGLD
                     PQATRDVRKIITDLATQGTSFLISSHLLSELEKMVDELILINQGKIIKQCTMAELNQT
                     AQDFIVISTTNDLAARTILTEAGYTLEDPDKIKLLKENEELLGTVIQLLSAQNIHVTD
                     VQHLTNDLESSLLEILDSVKGEEEK"
     gene            complement(16315..16635)
                     /locus_tag="LLC22_003011"
     CDS             complement(16315..16635)
                     /locus_tag="LLC22_003011"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005877273.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="multidrug efflux SMR transporter"
                     /protein_id="HBK5436188.1"
                     /translation="MAWMELIIAGILEVFWSTMMKWSDGFSKINYSFYTVIGMIASFY
                     FLSKAIKSLPMSLSYPIWTGIGAVGSVIIGVVLFHDKLNLSTWFFVGMLLISIIGIKI
                     TSGH"
     gene            17109..17795
                     /locus_tag="LLC22_003012"
     CDS             17109..17795
                     /locus_tag="LLC22_003012"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010719881.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF969 domain-containing protein"
                     /protein_id="HBK5436189.1"
                     /translation="MENYLSLLGVLIVILGFAFKLDSILIVMVALVVTALTGGLGIQG
                     MLELLGTSFVNNRGMAIFIIIMLATGTLERNGLKESAASLIKRFKKVSAGMIVDIYGI
                     FRMIFAAFNVSFGGVAGFVRPIILPMALGTIESKGLEVHPKHEEELKGMASAMENVCW
                     FFGQVLFIGGAGALLVQSTLKDLGYDVTLGQLALVEVPVAITALVVASVYFYLKEKKL
                     AKKYYPGKGQ"
     gene            17797..18741
                     /locus_tag="LLC22_003013"
     CDS             17797..18741
                     /locus_tag="LLC22_003013"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002306105.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF979 domain-containing protein"
                     /protein_id="HBK5436190.1"
                     /translation="MDFFTNPDILLGDKLLEILYIVMGLVLIYTGVRNLTDKTNPHRY
                     GSAFFWTVLGVVIAGGRWLPAIVNGGLIFAMTIPAIAKKVSKGESRLPSKEYMEKMSD
                     KLGMKIFIPALSIGVFAILFALFTNLGALVGVGVGVFAAMLILMFFSRDNRPSTFLDD
                     AADMLGTVGPLSMLPMLLASLGAVFTSAGVGTVISNAVGTIVPEGNVNIGIIIYALGM
                     VIFTVIMGNAFAAITVMTVGIGAPFVFSHGANPALIGMVALTCGFCGTLLTPMAANFN
                     IVPVAMLEMKDKYGVIKNQLFIALFMLVFQIAYMILFK"
     gene            18940..19584
                     /gene="pcp"
                     /locus_tag="LLC22_003014"
     CDS             18940..19584
                     /gene="pcp"
                     /locus_tag="LLC22_003014"
                     /EC_number="3.4.19.3"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_010734749.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="pyroglutamyl-peptidase I"
                     /protein_id="HBK5436191.1"
                     /translation="MKVLVTGFDPFGGDKVNPAYEAVKKMPDEISGAEIIKVEVPTVF
                     EKSSQVVKEAIQQHQPDVVICVGQAGGRSAVSFERVAINLAEARIPDNEGNQPFDTAL
                     EENGPAAYFTSLPIKAMTKNVQDHGLPAYISYTAGTFVCNDIMYRLLHLIETQFPAIR
                     GGFIHVPFSPDQVIDRPVGTPSMSLEDIASSLTYAVEAAVENKEDISGNAGTTH"
     gene            19663..20940
                     /locus_tag="LLC22_003015"
     CDS             19663..20940
                     /locus_tag="LLC22_003015"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002336015.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
                     /protein_id="HBK5436192.1"
                     /translation="MEEWQSVFEEWFPKEISKSYPIKISKQYTSSQRWEIYAKLTKKQ
                     RELVDKHRRYLISSRFMEEHYLAATDWVFSDFKINPFFRTKRSQQKLYCECGRELKVQ
                     YIVKSPKTGKILKLGINHFADHLHVSPTVAASIHQGMTKVDLALDELLWLKQKNIDFP
                     EGLWQKYCFVLYQNRRMKQPYLPDIKLAQRLAEFRQVEMPIYIADYQALENEIKKISE
                     HINGQSKKRQIKKELFDDFAEELVKDVEEFLINYRAFLRKDWQSIVYEEVPVHPNAYF
                     ETFISVLRKTKRQRTPEVTAQMEYFAKNQRFIQPKIYLFIWKQYCHYGFTEGFFDSIP
                     RIVRNGFLKVLRKEREAIQSADKKDRTVSKEKWQLVVKDIQSGNVQETIDKWKGKHYR
                     FTEAQKQALEYYQKLEESLRFNDEARKYLKELL"
BASE COUNT         6778 a         3784 c         4362 g         6061 t
ORIGIN      
        1 ctgttcttat tacttgatgc agggcagctt tttcacaacc ccttattcac ggcgttccag
       61 aagtagcttc ttcttatttc ttgaagctga taacttctgg aacatcctct ttttttattt
      121 ggacggataa tggtcattcc atttctttga tcattttttt cattttgtcg atctcttctt
      181 cttgtgcctg aatgatttct tccgctaatt tttttacttc aggatctttt aaatcagctc
      241 gtttacttgc caggatagcg atagaatgat gaggaatcat ggccttcatc caagctgtgt
      301 cgttgacagt agtttggctt cgtaccataa acaaggaacc ggcaaaaaca agaagactag
      361 cggctaagat cataacattt atctttttgt tttcatacat tttccacatg aacaacagca
      421 tgatgactgc catgactgca cccatcatca acgccatgaa tactcgtgta cgactgaaga
      481 agatatgatc gagcgcatag acattcaagt acatcatacc aaacataact accgttgaaa
      541 caccgatcat caacaaaaac ttccaatact ttttcattta aaacaaactc ctttttttca
      601 ttcctttctt ctatcatgtc atgagcatgg agaacaatca attattttgc acagagggtt
      661 tttgaacacc gtttaccaag aggtcatgag actgtttatt cggaaaaagg agttgcaaca
      721 agacttttgt cacaactcct ttcttcaata gctccatcta ttccacataa ataaaataaa
      781 attttctatc gatttcattc attcgtcaat acgaacgcat cattcttttt ttgataactg
      841 aaataaatga acaggtaaag caggccagtc aatacagtta ccccaatgga gttcgtgaac
      901 aggataccaa ggaaaatcaa tcctaagaca gctaatgcaa aaaagctgat tcctttatcc
      961 cataatgttc cttttcttag tgccagtaca aaggatgccg cactgataat gatccagatc
     1021 aataatactg tatacgaaag ggaacctgcc agatagccaa ataatttgtc accgacaaaa
     1081 taagaaagag ctacaccaag ataaagaaca ctggtacaaa ataaaacagc acgttgcggt
     1141 acttgatgct tgtttaaaac agctagtttt ctagaggaac cttttcgatc cttcaaacgg
     1201 aagaacaaaa ttcttgaaga tgcatacaca cccgaattga tagatgagaa caaagcaagg
     1261 acaatcacaa aattgacgat atccgctgca aatgggatat tcattttttc aaataccatc
     1321 acaaaaggac tgacattcgt gcctgctaaa gtattccaag gaaaaagaat caaaagcaaa
     1381 aacaaaggaa tgatgtaaaa ggaaatgatt cttcccatga cacctttgat tgctttagga
     1441 atcgcacgtt taggatcatc tgcttcgctt accgtgatag caatcagttc agaaccgccg
     1501 taagaataga taactacaag caaagaactg atgattccct tcataccatg aggagtaaac
     1561 ccaccatggt cagtcaattg ctgaagggta gggaaaacgc ctgtgcccaa catttgctga
     1621 ccgacaagat aagtagcaaa aatgatcagt aagataatga cactgatttt agcaaaagcc
     1681 agccaatatt ctgtttctgc gaataaccgt accgaataaa gattgatgat cgtagttaaa
     1741 acagccaaca taaaaacaaa tacccaggct ggaatgtgcg ggaaccacaa ctgcaaaaag
     1801 gaagcagctg caacagcttc agcgatgata ttgataatcc acatagacca gtagacccaa
     1861 tcagtaaaat cagcagaatg agcacctaga taagggcgta tcaaaccaga taatccgtga
     1921 tgcgtgtcgc caccgcttaa aacgattttt cccagacctt tcatcacgat atataaaatc
     1981 agcccaccaa tcaaaaaagc aatcaataca gaagggccgg cgatcccaat cgcttcgcca
     2041 cttcctttaa atagacctgc accgattgct ccacctaaag ctaacatggt gatatgtctg
     2101 gagctaagtt gttttttcaa ttttttatct tccataaatg acctctttct tttaaattca
     2161 caatcaaaat ttatattaag aataaatagc aatatttaac aatgactaat gataacaaat
     2221 tttcagacaa ttacaactat tcagaaaact tttaggcgaa ttttaataga agaatgattt
     2281 atttcatcat attttcatac aaatgttaaa ttttcataca aatataggaa acgttttact
     2341 ggctttttac tatttaaaca ggctatcata ggaaaaagtg acagagaaag tgaggcggaa
     2401 aagatgaaca aaaatgacgt actgctagtt gcaaaaaata aatcacttta ttttttgcct
     2461 tccatccgct ctttagatgt ttggtccgga aaagatttac tacagtcgga attcattaaa
     2521 tcagctagac aacagttggc aaattatcag ctgatcgttt ttttagatta tggatttgat
     2581 atggagatgg ctcgacgcgt gcgcccattt accaatgcaa aaattgtgtt atttttttgg
     2641 aatcacttca aagcagaaca cgaggcgatg ctgaagcagg cacaagatga accggcaatc
     2701 gatgagattt atcattttga ttttttggaa gcaaaagaac ttgggctgaa acataatagt
     2761 tcattttatt cgaaacatat gaatttttct tctagcgaac caaagacgga tctatttttt
     2821 ggtgcaacga ataatgggag aaaagaacga gcagaaagct ataagcagga atttataaaa
     2881 agagatgtta cgaccaacta tttcattctt ccacatcgag ggaatgaaca acctggatat
     2941 cttacttatg aagagtacct gaaaaaaaca ggggaatcgc gcgggattct ggaactgttg
     3001 cgggagggtc agcaaggagt gactttgcgg acatttgaat ccatgtattt tcaaaagaaa
     3061 ctagtgacgg ataatcaagc gattgctcat tatcattttt atcgtcctga aaatattttt
     3121 ttgcttcgag aacgtgattt agatgaatta ccggaatttc tgcatacacc atttaagcca
     3181 atcctatcag agctattgga attttatgat gcagaaaatt gggcaaaacg atttatcact
     3241 aacgattcca ctatttatga gcaatacgaa tatgacctct cctctgttga aaacaaataa
     3301 aaaacctaca ttttgaagag attatgtact gaaacaaaca agcacaattc ttatggcatc
     3361 atgagagttg tgttttcttt ttgatctttt attgggctta aaaaaagaga accagctgct
     3421 gattcagctg attctcatca gagagccttt tattctgcgc caaggattcc ttcttttgca
     3481 tggactaatt gggtcaaaaa ggcacaatat ggtgtagcaa tatcatattt ttgtcctttt
     3541 cgccaaatgg caccattgat gtagtcgatt tcagtcaaac gatggttttt gatcaggtct
     3601 tggtacatag atgggtaatg caacccgatg ttgtcaggat cataagtaga agcaatatgt
     3661 tggtacactt cttcttgatc tagtatgatt ccttcttttg ctgcgataga agcaaattca
     3721 gatacgattg ttcgaaccat gctctctgcc gctttttgcg cgcctagttc agcaatatta
     3781 caatccaaaa tcgtgcataa accattcaat gttccattta cacaagcttt tcgccaaatg
     3841 gaataacgaa cgttatggct atagatcgga tttaaatttg cttcttgaaa gacttctaca
     3901 actttttttg taaatgcttc gccttctggt tccaagttct ctagttcgat ttctccatca
     3961 cctaacaatg tgacttttcc gggaccagct agaccagctg tccacatcgt gatcccaaat
     4021 aagatatttt tctttggcac atatttttcc agtacatctt catgacctaa tccatttagt
     4081 aaacacaaaa cataagtatt gtcagtaata atggattgga tcgaacaaaa catatcatct
     4141 aattgattgg cttttgttaa tgctacgatc aagtccacgt gttcgttgct ttcgatgatt
     4201 tcttctggtg aatagattgg cagttttgcg accacttctt taccgttaaa gtcagcaatc
     4261 aacccatttg tacgaatggc ttcaatgtga gcaggccaac gatcgatcaa gaggacctca
     4321 tttccgcttt gatgtagcat caatccgatt cggctgccca ttgctccggc cccagctatt
     4381 gcgattttca tgttttttct ctcctttatt caatgagttc ccttttagta tatagaaaaa
     4441 tggaagaaaa tagcattgtt ttgtttgaaa aaaatgaaaa aaagtgtctt acttaagaag
     4501 aaagtgaggg atacagatgg atattttggc ggcaattgat tcatttaaag gaagtgcttc
     4561 ttcatttgaa ctaaatcagg cagttctaaa tggctgggaa gatcgtaaag gaagaaaaat
     4621 caatgtgccg attgcagatg gcggagaaaa tactgcagaa gcaatctatt acgcgctcag
     4681 gggaacatgg cgtaccattg atgggatgga tctcttattc cgtcagcgaa aaatcagcta
     4741 tttattgaca acttggcaag gaaaaaacac cgcagtcatc gaatctgcac aagcattggg
     4801 gttagatcta cttgataaac caacggatca aactatccga cttgcttcca gttatgcctt
     4861 aggagaactt attaaagatg cactgcttca agaagtagaa caaattattg tcactttagg
     4921 aggaagcggg tgtagcgatg gtggtctagg attactccaa tccttgggtg cttctttaga
     4981 agggtacaca gaaggaaatc ctttattatc tactaaaaaa cttcattttg atcgaagaaa
     5041 cgttcttgtt tctaaagtaa aattgattat cgctgcagat gttaccaatc catatacagg
     5101 tcaacaagga gctgcttggc aatttggaag acaaaaagga ggaatagata cgacgctagc
     5161 tttcttagat aaacaagcag gaaagattgc tcagcaaata aaagatttct gggaggtgga
     5221 tttagatgat attccaggaa gtggagcagc aggcggtatt ggtggagccc tttttttgtt
     5281 gggagcgaag atggtttctg gtttcgattt agtcagccaa atcactggat tggaaaaaaa
     5341 gatcgaacaa gcagatgtca tcattacagg agaagggcgg atcgatcagc aaacgatcca
     5401 cggaaaagtt ccatacggtg tagcagtgct tgcaaaaaaa tatcgaaaac caataatcgc
     5461 tatttgcgga agtagagacc aagagctaga aggactttct gattttctcc caattgtctt
     5521 aagtattcat ttgggtccaa taggtttaga agaagcaatg gaacacaggc aaacattaga
     5581 aaaaacaaaa atcttaggac agacacttag cagatttttc accatcctcc cgaagtagtt
     5641 gacaaaatca ttttctttat gctatcgtaa tttcaaatat aggacaaagt gagggatccg
     5701 tgcattgaaa aattaagtcg attgatgaaa gctgcattca gactgtacct tgtggagaca
     5761 aggaagcagt gtgcagattt tcgggattgg cttggttttt tcgatgtatg ggtctttttg
     5821 tgtgtatcca acccttgcat cctctttagc cagttctgaa aataggactg gtcttttttt
     5881 acgaggtgat ggaaaatgtc taaaatcgaa ataaaaaatc tgacattcgg ctacgacagc
     5941 caaggcacat tattatttga acaagcaaat ctaaattttg acacacaatg gaaactagga
     6001 cttatcggac gaaacggtcg aggaaagaca actttactga atattctaca aaacaaacta
     6061 ccttatcaag ggcaagtaat ccatcagcaa gaatttgcct atttcccgca acagacaaaa
     6121 gataaagaac gtttaaccta ttacgtgtta aatgatatta cggattttga gatatgggaa
     6181 atcgaaagag agctccaatt gatgcaaaca gatcctgaaa tcttatggag agaattcagc
     6241 acactatcgg ggggagagaa gacaaaagtc ctactggcac ttttatttgt ggatgacact
     6301 catttcccgt taatcgatga accaacgaat catttggata tctctggtag aaaacaagta
     6361 gcggcttatt tgaaaaagaa aaaacaaggc ttcatcgtgg tcagccatga ccggggattt
     6421 atcgatgaag tagtggacca tgttttagca atcgaaaaaa gtcaactgga actttatcaa
     6481 gggaatttct ctatctatga agaacagaaa aaacttcgtg atgaatttga aatggctcaa
     6541 aatgaaaaat tgaaaaaaga agtcagtagg ctaaagaaaa cagcagctga aaaagccgaa
     6601 tggtctcgtt cccgagaagg agataaaaca aagaaacaag tcggattcat cgatactgaa
     6661 tctagacgag tgaataaagg agcagtgggt gctgatgctg cacggacgat gaaacgatcc
     6721 aaagcaatcg tgaatcggat ggagacccag atcagcgaga aagaaaaact attaaaagat
     6781 atcgaatata tcgattcttt gacgatgaat agccaagcgt ctcaccataa gcgactttta
     6841 agcgtagaag atcttcaatt agggtatgaa aatctgttat tcgagccaat tcattttaca
     6901 atcgagcctc atcagcgggt ggcgatttca ggtcctaacg gtgcaggaaa gtcatccatt
     6961 atccattatc ttctgggggc attcaacggc aaggttatag gagaaaaata ccagccaaaa
     7021 catctgagca ttagttatgc aagccaaaat tatgaagaca atcgaggaac gttggcggaa
     7081 tttgcagaga aaaaccaagt agactaccaa gcatttttga acaacctccg aaagcttggg
     7141 atggaaagag atgtttttca taacaagatc gagcagatga gtatgggcca acggaaaaaa
     7201 gtggaattgg ctaaatcttt atcacagcca gctgaactat atacatggga tgaaccattg
     7261 aattatttgg atgtcttcaa tcaagaacaa ttagaacaac tgatcttgaa cgtgaaacct
     7321 gccatgttac tagtggaaca tgatcaaacc ttcctggata aagtatctac tgagattatt
     7381 tctcttgaga gaatctaacc cttgtaatct caagaacaac aaggtatggt taaggggaac
     7441 tttgccaacg aaggagagaa tcacatgctt tatgtaacga gacacggaga aacaacttgg
     7501 aacgcacaag gattagtttg cggacgggca gatgtgccgc tgactgaaaa aggacagatg
     7561 caggcacaga aactagcaga aaaggtagta gatttgcctg ttccaatcac gaaaatcatc
     7621 cattcccctc ttcaacgagc aagagataca gcacaagcag ttgctgatcg tctcagcttg
     7681 ccgctgaccg ttgatgaacg attggtagaa atggattttg gggattatga tggactgcca
     7741 agcaaagatg agaactttca aaaagcacgt ttagcgttcg ctgtacgatt cccaaatggg
     7801 gagtcagtct tagatgtgta tgcacggatc gttcctttat tgaaagaatg catcgaagac
     7861 gaagaaaatg tctatctgtt agtttgccat aatgccttga taagagtgat caatgcttat
     7921 tttcatccga tgcctaatga ggggttcttt acattcatgg tagataatac agaattggtt
     7981 tcttatgagt aattatgttt ttgtgttatt taaataaaat atttcaaggc actgcttttg
     8041 cttagcagtg ccttttttag gttatgacaa ttcttttgat aatataaact caacctttag
     8101 aaatgaaatt taattatttt aataaaagta ttgaaatttt gtttctttag atatatactc
     8161 tagtcataga aatgaagacg gatacagaaa aagagggata atatgtttgg cttttcaata
     8221 tttatgaacg attctttgtc agaagagaag aaacagtata tccgccaaat ggcatccaat
     8281 ggctttgtcg gtattttcac ttccatgcat ataccagaag atgatgtttc ggcatatcaa
     8341 aagcgattga tcgaactagg aagcgaagcg aaaaagaata aactagaatt gatggtcgat
     8401 atttcaggag aggcattgga acgagcgggt ttttcattag aagatctaac gcctttgaaa
     8461 gcaattggtg taacaggttt aagaatggat tatcatattt ccaatcagca gattgccgac
     8521 tggtcacatc aattgaaaat cagtttgaat gctagcacga tcacgcctaa agatatcgat
     8581 gaattgaaag aagcagaagc tgatttctca cagattgaag cttggcataa ttattatcca
     8641 cgtcccgaaa cagggctgga caaagaatgg tatcagaaaa aaaatcaatg gctcaaaatt
     8701 caaggtctcc ttgtccaagg ttttgtacca ggagatacag agttgagagg cccactatat
     8761 caaggattgc caactttgga agaacatcga gggatccatc ctcttgcagg cgctctagat
     8821 ctattagcaa gtaacacgga tattgtttac atcggagatg caggtctgtc agaaaacgtt
     8881 caggagcaat ttgcttcttt ccaaaaagaa cagacagtct tgctccatac ggaacctgta
     8941 gatgaagaat tttacgaata tatattaggg aagcatacga atcggcaaga cgatgcaaga
     9001 gatgtcatac gaagcgtaga tgcacgtttt cgagagattc cgcctatccc agcaagaaat
     9061 acagctacgc gtatgaaagg gtctattact ttagataacg aaaagtattt gcgctatatg
     9121 ggtgagatcc aattaaccaa atatgatttg ccagcggatg aaaaagtgaa tgtagtagct
     9181 aaagttatca aagaagagct accattgatc aaccaaatca aagctggtat gaactatcaa
     9241 tttataagaa aagaaggaag ataaaaatga gcaaaatcaa tttagagaac ctaacaacgg
     9301 aacgcagaaa ccaagaaact tttggattag atgagatgag tatttctcaa gccgttcaac
     9361 taatgaacaa agaagatcag aaagtggccg ctgcggttga aaaagaactg acaagtatcg
     9421 aaccagtgat tgctaacacg attgagtcct ttaaaaaagg tggacgtctg atttatatgg
     9481 gagccggaac aagtggaaga ctaggtgtgt tagatgctgc tgaatgcgta ccgacattcg
     9541 gtgtagaacc ggaaatggtc ataggtctaa ttgctggtgg agaagaagca atgactgtag
     9601 ctgtcgaagg ggccgaagat tcttatgagc tagggcaaga agatctaatc aagctgaatt
     9661 tgacaaaaaa tgatatagtt attggtatcg cagctagcgg tcgtacacca tatgtgatcg
     9721 gtggattaga ttacgcaaaa tcgatcggtg ctgtcacagg aacgatttct tgcaataaac
     9781 aagccgaaat cagtaaacac gcggatttcc caatcgaagt cgatgcaggt ccagaatttt
     9841 tgacaggctc tactcgattg aagtcaggaa cagcacaaaa acttatcttg aatatgattt
     9901 ctactatcag tatgattggt ataggtaaag tattcaataa cttgatggtc gatgtcaaac
     9961 caacaaatga aaaactaatc gaacgctcaa aacgaatcat catgcaagcg acagaagctg
    10021 attacgaaac agctgaaaag tactttgaag aagcagatca aaatgttaag ctggctatcg
    10081 tcatgatttt gacaaatagt gataaagagg aagctcaagc aaaattagct gaagcaaacg
    10141 gatttgtaaa agggacctta tgagggggaa aagaccatgg caaaaaacga actgactttg
    10201 gaagaactgg caaaacaaat ttataaaggg gcaggcggca tgggcaatgt agaaagcatt
    10261 gtccactgca tgactcgtgt gcgtatgaag atcatcaatg atgatcttgt aaatgtctct
    10321 gaattaaaag cgattccagg agtgcttggt gtagtagaag atgaacagct tcaagtcatc
    10381 atcggacctg ggaaagtgaa caaagtagca cagcaaatgg ttgatttggc aggcgtgaaa
    10441 ttaggagaaa aactttcttc tgtaagtaca gctacagcaa attcatcagc atctggaaaa
    10501 gaccgtgtaa acgaacgggc acaagaaatg aaagcggcac aaaaatcgaa acaaaaacca
    10561 tctaaaatca aatcggtatt aaaagacatt tctaatatct ttgtgccaat gattcctgca
    10621 tttgtcggta ctgggatcgt ggcagggatt gccgcagttt tagcaaactt agtcacagcc
    10681 ggaacacttg atgcagcaac atggcaacaa tatatcgatg tgatgaacat cttgaaaaac
    10741 gggatgttta gctacctagt tatctataca ggtatcaatg ctgcacaagt ttttggtgca
    10801 acaccaactc ttggtggagt tatcggggcc gttgtgatgc tgacagggat gaatccggaa
    10861 gcaccactga aaaacttatt tactggtgaa gctcttgcag ctggacaagg tgggatccta
    10921 ggtgtcatct tcgctgtttg gctattgtca atcgttgaga aaaaactgca taaagtagta
    10981 cctgatgcgg tagatatcat cgttacacca actctttcgt tgattgccat cggtctgatt
    11041 gaaattttct tcatcatgcc tttagcaggt ttcatttctg atggcatggt cggtgggatc
    11101 aactgggtac ttggcgttgg tggagcattt gccggcttcg ttctaggcac attattcttg
    11161 ccgatggtta tgttcggact gcatcaaatt ttgactccaa tccatgtgca aatgattgat
    11221 gaaactggtc gtacgctatt gcttccaatt cttgcgatgg ctggtgcagg acaagtgggt
    11281 gcagcattgg cattatggat tcgctgcaaa aaagataaag aattaacaga aatgatcaaa
    11341 ggagctttac cagtcgggat cctaggaatc ggcgaaccat tgatttacgg agtaacatta
    11401 cctctaggac gcccatttat tactgcttgt atcggtggag gtatcggcgg ggcagtgatc
    11461 ggaatgatcg gaaatgtcgg ggctatcgct attggacctt caggagccgc tttgatccca
    11521 ttgatctctg acggtaaatg gttaggctac atccttggat tattggcagc ttatgctggt
    11581 ggcttcgttg ctacattctt cttcggtatt cctaaagacc gtttagaaaa agaagaatta
    11641 gcgactgaaa cagccacagt aaatgaagtg cctgaaaaag tagtacctca aacttcagct
    11701 gaaagtgtga ctatcctctc atcagttgct gacggaacag ttgtttcttt agataaagca
    11761 agtgatccag tttttgcaca aaagatgatg ggtgaaggct actttgtaga accagaaaac
    11821 ggacatatct attctccagt tactggggta gtcagctctg tcttcccaac gaaacacgct
    11881 attgggatca caacgccaaa tggtttagaa atcttgcttc atatgggaat caacacagtt
    11941 gacttaggcg gtacgccatt tgatgtgaaa gtaacagaag ggcagcaagt gacacctgat
    12001 acgcttgtag cagaagctga cttagaagcg atcaaagcag caggcaaaga aacatccatg
    12061 atcgtcttgg taaccaatat ggatcgtgta aaaaactttg tcttggaaaa aacaggtaaa
    12121 gcaaaagcaa aagcacctgt gatggatgtc aaagcttaat atgatagaaa caatagaaac
    12181 gaaagaagaa actgaaatct atttttcagc ttcttctttt ttattattta ttgttttctg
    12241 ctaaaatctg ataaattcgt gtcacatcag atggtgttcc ccgtaattca taatctgcca
    12301 agaaaggaaa gccaaatgtt tgtgcatatt gtttggctgt tagacaatac tgattattga
    12361 agtttttatt tccgctaccg actacaccaa gacaaagttt atgattgtct tcatgttcca
    12421 gatattcacg catcgtttcg gtcaagattt ctgtatcacc gttatctaaa ccatttccgc
    12481 cgtctaaata agtaggaacg aaagtaaaaa atggttctgt ttctttcgta aaatcactat
    12541 tttcatggat ttcttttaaa gtaacttcag gattgacagg atcttctgca tgcatttttt
    12601 cagcatattc tgctagatgt ttggcaaagg cacgcgtatt tcctgaaatc gatatatata
    12661 aaatgttcat ggatcatcct ccaattcttt ccttttagta tagcatcttt tttaagtttt
    12721 ttggtggtgt aatttggaaa gggactaggc gctttgcttg tataatgaga aaaaagccgg
    12781 tagaattata tttctattaa agtttttatt aattaagtaa aaataaaaaa ggtttgttat
    12841 actttttgat aaaagcggtt ttattttgga ggatgcttac atggatacag agcaacagaa
    12901 aaaaggaatt ggtttaattc cacttgctgc cttagtaatt ggttcagcga ttggaggtgg
    12961 cgtatttggt attatgacgg acatctccgg atcggctggc ggcccagcta ttttcagttg
    13021 ggtactcgta ggaacagcaa tgttgatgct ctccttgtcg atcaataata tcaataaaaa
    13081 acgtccagat ttaaaaggcg ggatctttag ttacgcagaa gaaggttttg gccgtttcgc
    13141 tggttttatc agcggttggg gttactggct cacatgctgg ttaggcaacg tagcttttgc
    13201 aacattgttg atgagcgcat taggatattt cttcccagta tttgaaggtg ggcaaaatct
    13261 ggcatcgatc gtgatgagta cagtcttttt atggggatat gcatggctag tgaatcgggg
    13321 agtcgaaaat gctagtttcg tcaatgctat cgtcacattc tgtaaattag tgccattatt
    13381 tttatttatt gtagtagcta tcagcacgtt ttcgatccaa caattcattg ataacttttc
    13441 tagcgacatt atattgaatg cgaatggaca gccgatcccg ttttccagtc aagtattgag
    13501 ttgcatcatg gtgatgcttt gggtatttgt tggtattgaa ggagcctctg tcgtaggttc
    13561 acgagcaaaa aaacaatcag atgttgggaa agcaacgatt ctagggatat tcggcttgat
    13621 tattatttac gtcttggttt ccatgcttcc atatgggaca atgacgatga atcagctgca
    13681 aacgatcaag gcgcagcctg ctatgggcta tgtgtttgaa atgatggttg gtaaatgggg
    13741 agcagtcgtg atcaacggcg gtttgatcat ttctttagtt ggtgtttggc tctcatggac
    13801 gatcttaccg attgaaacaa tgggaaacat ggctgaagac ggacttttgc ctaaagcatg
    13861 gggaaaactc aacaaaaatg gggcaccaac ttatgctatc gtattgacga cgttatgtac
    13921 gaatgtcttt ttactttcat tattattcac tgacagtgct tataactttg cttacacact
    13981 tggtacagca gctattttct tcacgtggct tttcttagga ttgtaccaaa tgaaactttc
    14041 ttatcagcgg aaagaatggg tccaattttt agtagggctt ttagcaagtg cctttcaagt
    14101 atgggctatg ctagtcgtag cctttaatga agtaatgctt gttcttgttc ttttcttgcc
    14161 aggcatttat ttttacctca aagcacgtaa ggagcaaaac gagcctgtac aacatatcca
    14221 cttagataag attttactta taggtgtgac gatggtcgga gtgattgcaa tggttttatt
    14281 tgccactggg atgcttcacg tatagaagta taaaagaagt ataaagagag gttgtgagcc
    14341 tgtcgtttat tcaaaaacat actaggaaag gagctgtgac acaaatgttg tcacagctcc
    14401 tttttcagaa taaacggtgt ttaagagaca gccaatcggc aataaggctg aacgtctctt
    14461 tcacagcctc ttttttgatg agtcatcata cattttttcg cttaaatacg agatatccta
    14521 atgctaagaa caaaacgatg taagctaaat taccgaatag catttgatta gtagaaagat
    14581 gagtcaattg cttcatgatc tcttcgtttc caatttggtt ttgcagattc aacatactga
    14641 tcggattcca tttgatccac tcccattttt ggatgagtgc aataaggata ccagatatga
    14701 ttgacgaagc aaaataaaag acgattcctg ctgagatgga tgcgccggaa ctattgataa
    14761 agcaagcaat catcaacact aaacttaaaa tcagccataa accgatataa ctacccaaag
    14821 tataagtgaa caagctttgg atcagtgttt gaccagtaga aaccttctcc gtgaaggaaa
    14881 tcgaagggaa aagaatcagt ttcatcaaca cagtgacaat aatagctaaa aggtataaat
    14941 aaacagaata aataactaat gtgatccatt tgcttactaa tatttctcct cgagaatact
    15001 ttcgataaag gagatttttc aatgtaccat attgtgcttc catcgaaatg atcgtgcttg
    15061 cagctgcaat catgataaag acaatccaag atgtggcact aaaaagctga gcagtcattt
    15121 caactggatc aatgatcgtc gtgtattttt tggctagaag tgctgttcct atgagcaaaa
    15181 caactaatag aacagataaa acagcagttg actttttctt gatcaattta aataattctt
    15241 gttttacaag caatgtcatt tttcttcttc cccctttact gaatccagaa tttccaatag
    15301 agaagattcc aaatcattcg tcagatgctg gacgtctgtc acatggatat tttgtgcaga
    15361 caatagctgg atcacggttc ctaataattc ttcgttttct tttaaaagct tgattttatc
    15421 aggatcttcc aaagtatatc cagcttctgt caagatcgtt cgagcagcta gatcatttgt
    15481 tgtagagata acgatgaaat cttgcgctgt ttggttcaat tcagccattg tacattgttt
    15541 gatgatcttt ccttgattga tcaggatcag ctcatcgacc attttttcaa gctcgctgag
    15601 taagtgactg gagatcaaga aagaggtgcc ctgagtagcc aagtcggtaa tgatttttcg
    15661 cacatctctt gttgcttgtg gatccaaacc gttcatcggc tcatctaaaa taacgataga
    15721 cggatggttc agtaaggcaa gagcaattcc caatttttgt ttcattccca acgagtagga
    15781 tttcgctttt ttgtgaatgt acttttccat cttgagctga ttcacgatag tgtcgatagc
    15841 agatacatcg ttggtttcag agaataactt cagatgatca tagcctgtta agaatggata
    15901 gatacccggg tattcgatca atgctcctac ttgttccaac cctttatgac tagagggaga
    15961 aatctcattt tcaccaatac agattgttcc atctgagtaa tggatcagtc ctaaaatagc
    16021 tttcatgatc gttgtttttc cagcgccatt aggacctact aatccaacga ttttgccagg
    16081 ggataagcta aaactgacat cgctgagggc ttgtttgtga ccaaagttct tggataattc
    16141 ttggaccgaa agacttttca aaaatattca ctccttttct atagatagta caagcataca
    16201 cctgatgagt ggagaagtcg ctaggtcatt ggacttattt cttatttttt cataaaaaaa
    16261 ttgaatatta aataaaaagg cttatttttt ctgatcagta cttattccaa gtgtctagtg
    16321 gccgctagta atcttgatgc caatgatact gatgagtagc atccccacaa agaaccaagt
    16381 ggaaagattc agcttatcat gaaacaagac cacaccaatt atgaccgaac caactgcgcc
    16441 aatccctgtc cagataggat aagagagact catcggcaaa cttttgattg cctttgacaa
    16501 aaagtaaaaa ctagcaatca tgccaatcac tgtgtaaaaa gaataattga ttttagaaaa
    16561 accatcactc catttcatca tcgttgacca gaatacttcc aaaattcctg ctatgattaa
    16621 ttccatccat gccatactta cattcctcct taactataaa aaaatacaca aaaagaggaa
    16681 aatcatccct tcaaagacct aatggaatga tcatcctctt tatcctaccc ggtggcagat
    16741 tgtatatctt tttctgtagt atagcacacc tatccagata tcggcaatct catacttttt
    16801 agtaaagtgt accaagcact gacggatata tcgttagcgg aaaagaagat gaatgctttg
    16861 caatttcata gaaagaagtt gttatttatt aatcatttaa aaaaaacagt aactagacct
    16921 tatttctata tattatcggg caataaatta aaaaaagctt taccttacaa taagtaagat
    16981 aatttttgtg ataaaaaaat aacgaaaaat atttaaaaat agtgtctatt tcgtgagaaa
    17041 acaactatat tttttatgtg ttttgcttta taattaaaaa aatattgtca ttttatggag
    17101 gaaaatatat ggaaaattat cttagccttt taggcgtctt gattgttatt ctcgggtttg
    17161 catttaaatt agactcgata ttgatcgtaa tggttgcttt agttgttaca gctttgactg
    17221 gcggtcttgg cattcaagga atgttagaac ttttaggtac aagttttgta aacaatcgcg
    17281 ggatggcgat ttttatcatc attatgttgg caacaggaac gcttgaaaga aatggtctga
    17341 aagaatcagc ggcttccttg atcaagcgat tcaagaaagt atctgctggt atgattgtag
    17401 atatttatgg gatctttcga atgatctttg cggcttttaa cgtgagtttt ggtggagttg
    17461 ctggatttgt tcgtccaatc attttaccga tggcattggg gaccatcgaa tcaaaagggt
    17521 tagaagtcca tcctaagcat gaagaagaac taaaaggtat ggcttcagct atggaaaatg
    17581 tctgctggtt ctttggccaa gtactattca tcggaggagc aggggcgttg ctagtccaat
    17641 caacactgaa agatctagga tatgacgtaa cattgggaca gcttgcttta gtggaagttc
    17701 cagtggctat cacggcttta gttgtggcaa gtgtctactt ctatcttaaa gaaaagaaat
    17761 tagcgaagaa atattatcca ggaaaggggc aataagatgg acttttttac aaatcctgat
    17821 attttattag gcgataaatt actggagatc ctttatatcg tgatgggact cgtattgatt
    17881 tacactggag taagaaattt aacagataaa accaatcctc atcgttatgg gtcagccttt
    17941 ttctggacgg tcttaggggt agttattgca ggaggaagat ggcttccggc aatcgtgaac
    18001 ggtggcttga tctttgcgat gaccatacca gcaattgcta agaaagtcag caaaggagaa
    18061 agccggcttc catcaaaaga atatatggaa aaaatgtcag acaaactagg aatgaaaatt
    18121 tttattccag ctttgagtat cggtgtcttt gcgatcttgt ttgctctatt taccaattta
    18181 ggtgctttag tcggcgtggg cgtcggtgtt tttgcagcca tgctaatctt gatgttcttt
    18241 tctcgagata atcgaccaag tacattttta gatgatgcag cagatatgct gggcacagta
    18301 gggccgttaa gcatgttgcc aatgctttta gcttctctag gtgcggtatt tacaagcgct
    18361 ggagttggga cagtgatttc caatgcagta ggtacgatcg ttccagaagg aaatgtgaac
    18421 atcggcatca tcatttacgc tcttggcatg gtgatattta cggtaatcat ggggaatgca
    18481 tttgcggcca tcaccgtgat gacggttggg atcggtgcac cattcgtatt tagtcatgga
    18541 gcgaatccag cgttaatagg aatggttgca ttgacttgcg gtttttgtgg gaccctgctg
    18601 acaccgatgg ctgctaactt caatatcgtg cctgtagcga tgctggagat gaaagacaaa
    18661 tacggagtga tcaaaaacca gttgtttatt gcgttattta tgctagtttt ccaaattgct
    18721 tatatgattc tatttaaata atagaagaga ggggttgtga cagaataatt gtcgcaacct
    18781 cttctaacat tgtagtggaa cactattttt ttataagaat atattaagtt tgatctgtta
    18841 tgttatttaa actattgttt cctttattta cgctgttcaa ggaaaatggt atgataaaag
    18901 ataaccatat gttaaatcaa tcggacggag gaacaacaga tgaaagtact agtaacaggt
    18961 tttgatccat ttggtgggga caaagtgaat ccagcctatg aagcagtaaa aaaaatgcca
    19021 gatgaaatca gcggtgctga aatcatcaaa gtggaagtac cgaccgtatt cgaaaaaagc
    19081 agtcaagtag tcaaagaagc catccaacag caccaaccag atgtcgtgat ctgtgtcgga
    19141 caagcaggtg ggcggtcagc agtctcgttc gaacgtgtcg caatcaatct agcagaagca
    19201 agaatccctg ataatgaagg aaatcagcca ttcgatacgg ctttagaaga aaacggtcca
    19261 gccgcttact ttacctcatt gccaatcaaa gcaatgacaa aaaatgtaca agatcatggt
    19321 ctaccagcgt acatctctta tacagcagga acatttgtct gcaatgatat catgtatcgt
    19381 ttgcttcatt tgatcgaaac acaattcccg gcaattcgag gtgggttcat ccacgtgcca
    19441 ttctcacccg atcaagtgat cgatcgtcca gtgggtacgc cttctatgtc tttagaagac
    19501 attgcttctt ctttgactta tgcagttgaa gcagcagtag aaaataaaga agatatttcc
    19561 ggaaatgccg gaacaactca ctaatttagc aagaaacact ggctggttgc taacgttatg
    19621 ttagtagcca gctttttgta attagaaagg aaagaaacag ccgtggaaga atggcaatcc
    19681 gtctttgaag aatggtttcc aaaagaaatc agcaaaagct atcccatcaa aatttctaaa
    19741 caatacacaa gcagtcaacg ttgggagatc tatgcaaaat taacgaaaaa acagcgggaa
    19801 ctagtcgata agcaccgccg atatctaatc agctctcgtt ttatggaaga acattattta
    19861 gctgcaacag attgggtgtt ttctgacttc aagatcaatc cgttttttcg aacaaaacga
    19921 agccagcaaa aattgtattg tgagtgtggt agagaattaa aagtgcaata catcgttaaa
    19981 tcgccaaaaa ccggaaagat cctaaaacta ggcatcaacc actttgccga tcacctgcat
    20041 gtctctccga cagtggcagc ttcgatccat cagggaatga caaaagttga tctggcctta
    20101 gacgaattat tatggcttaa gcagaagaat atcgattttc ctgaaggact atggcaaaaa
    20161 tactgttttg tcttgtacca aaatcgtcgg atgaaacagc catatttacc ggatataaaa
    20221 ttagctcagc ggctcgcaga atttcgccaa gtagaaatgc cgatttacat agcggattat
    20281 caagcattgg aaaatgaaat caagaaaata agtgaacaca tcaatgggca gtcaaaaaag
    20341 cgacagataa aaaaagaact atttgacgac tttgcagaag aattagtaaa ggatgtagaa
    20401 gaattcttga tcaactatcg cgcattttta cgtaaagatt ggcaatccat cgtatatgaa
    20461 gaagtgccag tacatcctaa tgcttatttt gaaacattta tttccgtgtt gagaaagaca
    20521 aaacgtcaac gaacaccaga agtcactgct cagatggaat attttgcgaa aaaccaacga
    20581 ttcatccaac caaaaatcta tctatttatt tggaagcaat attgtcacta tggttttaca
    20641 gaagggttct tcgacagcat tcctcggata gtcagaaatg gttttttaaa agtattgcgt
    20701 aaagaacgag aagctataca atctgctgat aagaaagacc gtacagtctc aaaagaaaaa
    20761 tggcaactag tagtgaaaga tatccaatct ggaaatgtgc aagagacaat cgacaaatgg
    20821 aaaggaaaac attatcgttt tactgaagct cagaaacaag cgttggaata ttatcagaag
    20881 ttagaagaat cactgcgttt caatgatgag gcaagaaagt atctgaagga attactataa
    20941 aaaatagagg ctgggacaga agcgtttaac tccaagaaat aagaa
//
LOCUS       DAFBVQ010000235        16776 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.guided.058, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000235 DAFBVQ010000000
VERSION     DAFBVQ010000235.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 16776)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 16776)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..16776
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.guided.058"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            366..1229
                     /locus_tag="LLC22_003016"
     CDS             366..1229
                     /locus_tag="LLC22_003016"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002326092.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="AraC family transcriptional regulator"
                     /protein_id="HBK5436193.1"
                     /translation="MLKDLNQLIDYIEEHLTEGLSYKIIAENTGISEYQLKRIFTFIA
                     GMSLMDYIKNRRLALANRDLLDGSRVTETAFRYGYETVEGFSRAFRDWSGYLPSEISR
                     YGIQKSFPRLTFFIDVRGGKSMEFRIEKKEQFYVAGVAKKVPVKFEGVNQEIQKLAQT
                     ITETQREEMHKLGDLYPNQVINVSYGFDGDRLEEKGSLMHMIGFATTKENPYADLEML
                     AIEEHTWAIFPNKGPFPQTLQDTWGKIYAEWLPSSDYGLVEAPEISFTKWGEDFSNVY
                     SEIWIAVKAKK"
     gene            1329..1811
                     /locus_tag="LLC22_003017"
     CDS             1329..1811
                     /locus_tag="LLC22_003017"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325507.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="effector binding domain-containing protein"
                     /protein_id="HBK5436194.1"
                     /translation="MAKYRIEEKPDFTVTGIGVELKSSNTDFVGLAAEKQAFEQKVIG
                     NGTIDALKQAAENHYFFTVNEPYNGKMMYYVGVQTSQDVPNTTRIIPFPKGTYLVVSA
                     LAESPEELRNDLTNTAFGHVLREVEDYAYVGGPNAVVEMGVTNGKYMGEIWIPVVNKP
                     "
     gene            complement(2074..2541)
                     /locus_tag="LLC22_003018"
     CDS             complement(2074..2541)
                     /locus_tag="LLC22_003018"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002332248.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="Rrf2 family transcriptional regulator"
                     /protein_id="HBK5436195.1"
                     /translation="MKYSLQFSDAIHVLAYIEMFQDTRSLSSEMIASSIETNAANVRK
                     IMSQLKKSGLIFTKTGKPQPSLAKSPDQISLLDVYRSIEGNTQLIQVDPKTNPNCVVG
                     ANIQEALEESYARLQKKAEEEMAKITLDSLIHKIAVLEKEKRPENTGLVERFL"
     gene            2664..3515
                     /locus_tag="LLC22_003019"
     CDS             2664..3515
                     /locus_tag="LLC22_003019"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002376339.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5436196.1"
                     /translation="MHYLVTGATGGFGGYALEFLKKMVPQNEIYVLVRSEEKGEALKE
                     AGFNIRIGDYDDLDSMKEALKGIDRLLFVSGVPGNRQAEHKNVVKAAQAAGVSYIAYT
                     SFADADHSISVLAPDHQFTEKMIKDSGISHTFLRNNWYVENELPIIGQALKTGQFVYA
                     AGNGKTGWALKREYAEAAAKVLVESDSPEILELSGNLTDYEELAKALERATGKELEII
                     EASDAAFVENLKEAGFPQEAADMFLAIQHDIKKDQLAISSDDLEKVLGKPLTSLEAAL
                     KEILDQE"
     gene            complement(3766..5724)
                     /locus_tag="LLC22_003020"
     CDS             complement(3766..5724)
                     /locus_tag="LLC22_003020"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002335294.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PTS transporter subunit EIIC"
                     /protein_id="HBK5436197.1"
                     /translation="MKAYLQRMGRSLQLPVAVLPAAALLVGIGNWWASYSNDIVAHFL
                     QAGGNAVLGQLPLLFAVGLALGMSVDKSGAAALAGLVAFEVPVNVLKTDSVATLLNIK
                     PESVDPSFAQISNVFIGIIAGLIAAALYNRFHEAKLPMALSFFSGKRLVPILAAFVML
                     LISAVLLLVWPPVYSALVSFAKFILSLGWGGAGLYGFFNRLLIPTGLHQAMNSVFWFD
                     VAGINDIGKFLASEGTKGVTGMYQAGFFPIMMFGLPAGAYAIYRNARPENKAKTASLM
                     LAAAFASFFTGVTEPLEFSFMFVAWPLYVLHAIFTGISLAVSAFFHWTAGFAFSAGFV
                     DYFLSLKNPIANQPLMLIVQGLVTAVIYYFGFNFAIKKFHLMTPGREEADLSDDDTAT
                     TNSDNKYAAQASKIYAALGGADNVTSIDNCTTRLRLQVKDTGLIDQNKIKATGVPGMK
                     IIDGKNAQVIVGTEVQFVADEMAKLHGGAAARPAQTNTVVKTETFAGETIEQDIYAIA
                     NGKLIPITEVSDDVFAEKMMGDGYAVLPENGEIFSPIAGTITNIFPTKHAVGIQTDAG
                     IEVLLHMGINTVDLKGEPFTLYVEEGQKVARGQLIALVDLAAIQSAGKNTDMVVVFTN
                     GDKVQSLEIEPARDVKANDKIGSVSNKA"
     gene            complement(5721..6593)
                     /locus_tag="LLC22_003021"
     CDS             complement(5721..6593)
                     /locus_tag="LLC22_003021"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_005874851.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PRD domain-containing protein"
                     /protein_id="HBK5436198.1"
                     /translation="MKIKKIFNQNAVLVDDGGQEKVAIGKGIGFDRKRNDLIFDRDVE
                     RIFVMEPEGQIKLQNLLNQIDERFLFAAETIIDHAETVLMEKLNEHVLIALTDHIAFS
                     AENINNGIVIRNKLLREIEVLYSDEFSIAQWAVEYLTKELGIPYTYDEAGYIAIHIHS
                     GRSGRNNNHRSIREVTIVSDIIHLVESELETDIHSEPFSLNYSRLVNHLRLLLQRTHA
                     QQYAVLDTEIVEMVKRKYPESYKISKKIRVLLTKEYQLAITKEELGYLAIHIERLRSA
                     IVQTNVNNHEEEKN"
     gene            complement(6935..7807)
                     /locus_tag="LLC22_003022"
     CDS             complement(6935..7807)
                     /locus_tag="LLC22_003022"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629796.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="LysR family transcriptional regulator"
                     /protein_id="HBK5436199.1"
                     /translation="MDIRILTYFLAVAREKNISRAAKSLHITQPTLSKQLKDLEEELG
                     VTLFTRGSREIQLTDSGRYLYSKGKEILSLVEKTANNLTNDAIISGEIYIGGGETKAI
                     SFISDSLHSLIKAHPDIQFHLYSGNADDIIDKLDSGLLDFGLVIEPTNKQKYQSFRLP
                     AQDRWGLLIHRNHPLAKQTVIHPQELKTVPLIISRQTSVDSQLAEWLGFSIDQLSIVG
                     TYNLLYNASLMVDNGTFGALALDGIINTYGTEKIFIPLDPPLQASLNLIWKKDQPLSP
                     AARKFLDVLTEKYS"
     gene            7935..8504
                     /locus_tag="LLC22_003023"
     CDS             7935..8504
                     /locus_tag="LLC22_003023"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002337402.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="sugar O-acetyltransferase"
                     /protein_id="HBK5436200.1"
                     /translation="MTSLIEKQIVNKEIRVTDPLFEVIHQIQAENEEPLAALNTGYHE
                     PADIRKRLENIISDKVDDTVTVLLPFYTDFGKHISIGKNVFINRQVMFVDLGGICLED
                     SVLIGPRVNLITVNHLTDPKERRGLSVKPIHIKKNAWIGAGATILPGVTIGENAIVAA
                     NATVTKDVPDNTIVAGIPAKIVKPVERII"
     gene            8571..9308
                     /locus_tag="LLC22_003024"
     CDS             8571..9308
                     /locus_tag="LLC22_003024"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002325513.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="SDR family oxidoreductase"
                     /protein_id="HBK5436201.1"
                     /translation="MNDLSEKVIVIMGASSGIGEATTKLLAEKGAKLVIAARREDRLK
                     AIKESLPEAELYIQTADVRDFAQVQAVIDLAMEKFGRIDVLYNNAGIMPTAPLVEGHR
                     DEWQNMLDINIMGVLNGISAVLPIMEKQKSGHIISTDSVAGHVVYPDSAVYCGTKFAV
                     RAIMEGLRQEQRQNNIKSTIISPGAVQTELYQTISDKKAALELHEAQKEWGLTSEDIA
                     SAVAFAIETPDRMSVSNMIIRPTTQEV"
     gene            9539..10807
                     /locus_tag="LLC22_003025"
     CDS             9539..10807
                     /locus_tag="LLC22_003025"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344825.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 73 protein"
                     /protein_id="HBK5436202.1"
                     /translation="MKAKNLLFSVILLGNLAVANTTVLAEESTETVATQTSSSSETGI
                     ENDTESTLQSATVSENTISTEEPTTETTEQTQTEDSTSAEAQNNPENAEEITNQLTDG
                     QTLTHTHQADLSEFENYTGYAFYARSSANSQQAFIDSIASTAQSLASANDLYASVMIA
                     QAIVESGWGNSTLASAPNYNLFGIKGSYNGQSVTMPTSEYVNGQWITVNAAFRKYPSY
                     KESLQDNVTVLKTTSFQPGVYYYSGAWKSNTNSYKDATAWLTGRYATAPNYGSTLNNV
                     IETYNLTQYDTAPTSTSPMYRLYNRHTGEHLYTLNAGEKNYLPTVGWEYEGIAWQAPN
                     SGQPVYRLYNPYSGDHHYTMAQSEINSLTKIGWRYEGLSFYSGGSKPIYRLFNPNEKT
                     GTHHYTLSAKERDWLTPMGWRYEGIGFYGY"
     gene            11294..11758
                     /locus_tag="LLC22_003026"
     CDS             11294..11758
                     /locus_tag="LLC22_003026"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373333.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MarR family transcriptional regulator"
                     /protein_id="HBK5436203.1"
                     /translation="MSLEEISHLLYQIKLADQKIVQIFEENIGISLTRYEIMMRLKEE
                     NPLLQSSLQEKLQIDQGAVTRHLKVLEANGYVSRQRNPQNNREVYVALTEKAQKKIEH
                     CEMDHKDTGSVLSPAFSDVEMKQFLTLLDKLNTQLCNITTETKEVNNNGTKK"
     gene            11742..12371
                     /locus_tag="LLC22_003027"
     CDS             11742..12371
                     /locus_tag="LLC22_003027"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002287459.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nitroreductase family protein"
                     /protein_id="HBK5436204.1"
                     /translation="MEQKNDFSTIMTGRRSVRVYDETYKIPHEEMLEMIKEATTAPSS
                     VNMQPWRFVVAESEEAKEILRPLIRFNTRQNDTSSAMVMIFGDMQCYEYGEEIYNQAY
                     ESGKMPKEVRDQQLAAIIPYYKSFSREEMNDVVKVDSSLAAMQFMLVARDHGYETNPI
                     GGFEADQLAEAFGLDKDRYVPVIILSIGKAVEEGYESVRLAPEKITTFE"
     gene            12725..14204
                     /gene="msr(C)"
                     /locus_tag="LLC22_003028"
                     /pseudo
     CDS             12725..14204
                     /gene="msr(C)"
                     /locus_tag="LLC22_003028"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002314314.1"
                     /note="frameshifted; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="ABC-F type ribosomal protection protein Msr(C)"
     gene            14251..14697
                     /locus_tag="LLC22_003029"
     CDS             14251..14697
                     /locus_tag="LLC22_003029"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328790.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DUF2798 domain-containing protein"
                     /protein_id="HBK5436205.1"
                     /translation="MPTNKKEGIIFTTMMCFLMVLGMSAYNLWLHQDLHLSSLLIGLV
                     PGFVVAFILDVFIIGVLAKKIAFKLPVNPESKVQMILTISCLMVLGMVTCMSLFGVIM
                     EQGIPDQLFSAYMNAWKMNVIAALPLQLIIVGPLSRSVLKAIQSNE"
     gene            complement(14896..15411)
                     /locus_tag="LLC22_003030"
     CDS             complement(14896..15411)
                     /locus_tag="LLC22_003030"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629798.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="PadR family transcriptional regulator"
                     /protein_id="HBK5436206.1"
                     /translation="MNTLAYILLCVLLSKPRSGYELKQLITIFWEAHHSQIYTTLAKL
                     DQQGYVTVLDKDEHSQKKIYHLTDEGRALVEEWIKEETPAPTQKDEFLAKIYAFSTLD
                     KTTATGLLFTREQQLNKIMQKNQKKLNDLSLDKKQEFGRYVVIQRRIMLCQQELQWCQ
                     QVREQMQQFFE"
     gene            15528..16730
                     /locus_tag="LLC22_003031"
     CDS             15528..16730
                     /locus_tag="LLC22_003031"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002296013.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="MFS transporter"
                     /protein_id="HBK5436207.1"
                     /translation="MEILENQIDIQEQTNEETKGKSSALVVAATCMIAFMGVGLVDPI
                     LKTIAAQLNATPAETTLLFTSYMLVTGVVMLFTGFLSSRIGLKKTLMTGLFIIVVFAG
                     LGGLSGNIGMLIGLRAGWGVGNALFVSTALATIVSILVGNTEKAIMMYEAALGCGMAV
                     GPLVGGVLGSGSWRYPFFGVAFLMFCGFIALAVLLPETEKPKRKVGLWEGVKALSNHK
                     LRSVGLIALLYNFGFFTLLAYAPFLLIGYSELEVGFVFFGWGVLLAIASIFVAPALER
                     KFTTYRTILAAFVLFIICLLLLGAGTSMPVLVPISIVLAGFFQGIINTLLTTIAMEIP
                     GLQRNVASSSYSFVRFFGGALAPFIAGVIGEHIGESYAFYFAGAIVLISVCCIIYHRN
                     YFATNEEE"
BASE COUNT         5301 a         2988 c         3482 g         5005 t
ORIGIN      
        1 gatgaggttg aacttttaca caagattgtg gacttgactg caaagaaaaa tccaagcagc
       61 gttctgatca gcagtttgaa caacaatttg ctttgtacag taggtagtaa gcggattaac
      121 taagggaata aaagatattt ttaccgcttt gtttacttag aatctgtctt ccccaaaatt
      181 tatttttcta aaggtaaaac atagataggc agataatacc aattatccgt tacgaaacgc
      241 tgcttgagaa ttttctttag atccatacaa cattttctac atctgactaa attggttcct
      301 gattcatcaa gtaattgact ttctttgata atatgataaa aaggcaatca aggaggaaga
      361 taaatatgct taaagatctg aaccaattga tcgattacat cgaagaacat ttgacagaag
      421 gactttccta taaaataata gccgaaaata caggaatctc tgaatatcaa ttaaaacgca
      481 tctttacgtt tattgcaggg atgtcgctaa tggactatat caaaaaccgt agattggctt
      541 tggctaatcg cgatcttcta gatggatcaa gagtgacaga aacggcgttt agatatggat
      601 atgaaacagt cgaaggtttt tcaagagctt ttcgtgattg gtcaggatat ctgccttcag
      661 aaatcagcag atacggcata caaaaatctt ttccacgctt gacatttttt attgatgtca
      721 gaggaggaaa atcgatggaa tttcgtatcg aaaagaaaga acagttttat gtggcaggtg
      781 tggcgaaaaa agttcctgtc aaatttgaag gagtcaatca agaaatacaa aagttagcgc
      841 agacgatcac ggagactcaa agggaagaga tgcataagtt aggagattta tatccaaatc
      901 aagtaatcaa cgtttcttat ggatttgatg gagaccgctt ggaagaaaag ggcagtttga
      961 tgcacatgat tggctttgct acgacaaaag aaaatccgta cgctgattta gaaatgcttg
     1021 ctatagaaga acacacttgg gccatttttc ctaataaagg gccatttccc caaactttac
     1081 aagatacttg ggggaaaatc tatgcagaat ggcttccttc ttcagattat gggttagtcg
     1141 aagctcccga gatctctttt acaaaatggg gagaggattt cagtaatgtt tacagtgaga
     1201 tttggattgc agtgaaagca aaaaaatagt taaaaaataa aaatatccct agaaaaaaga
     1261 gcgtaatcgt gtcatttccc tttaatttta tgtaagatga acttaatata atagaaaggg
     1321 tgggagaaat ggcaaagtat aggatcgaag aaaaaccaga ttttacggtg acgggtattg
     1381 gtgtggaatt gaagagtagc aatacggatt ttgtcggttt ggctgcagag aaacaagcat
     1441 ttgagcaaaa agttatcggt aatggaacaa tagatgcatt gaaacaagct gctgaaaatc
     1501 attatttctt tacagtcaac gaaccctata acgggaaaat gatgtactat gtcggtgttc
     1561 aaacgagtca ggatgttcca aacactacgc gaatcatccc attcccaaaa ggaacgtatc
     1621 ttgttgtaag cgctttagca gaatcgcctg aagaattaag aaatgatttg acgaatacgg
     1681 cctttgggca tgttttaaga gaagtagaag attacgccta tgttgggggt ccaaatgctg
     1741 tagtcgaaat gggagttacc aacgggaaat atatgggaga aatctggata ccggtagtca
     1801 ataaaccatg ataatataga ggtcgtgaaa gtagcgcttt gacctgagca ttagagagga
     1861 aaaatgggaa atagctttcc atattttgca tttttcagaa ctaatgccga gggtcagcta
     1921 cttgaacacc gtttatcaag acgtcatgac ttcagcgctt tgacctgagc attagagagg
     1981 aaaaaggggc atgacaaggc ttttgtcccc cggagaataa aagaatttat gtagacgatt
     2041 ccgatcagaa aaatgcaggc acagtagaga gaattataaa aatctctcta cgaggcctgt
     2101 gttttctggt cttttttctt tttccaaaac ggctatttta tgtatcagac tatcaagtgt
     2161 gatcttagcc atttcttctt ctgccttttt ctgcagccga gcgtagcttt cttctaaagc
     2221 ttcttggata ttcgcaccaa cgacgcaatt tggatttgtt tttggatcga cttggataag
     2281 ctgtgtatta ccttcgatgc tgcgatagac atctagtaaa gaaatctgat ctggactttt
     2341 ggcaagggaa ggctgcggtt ttccggtttt tgtaaagatc aaaccggatt ttttgagctg
     2401 actcatgatt ttacgtacat ttgctgcatt tgtttcgata ctactggcaa tcatctcact
     2461 agaaagtgat cgggtatctt gaaacatttc aatataggca agtacatgga ttgcatcact
     2521 aaattgcaga gaatacttca tcagttgtca tcctttcatt ttttttgctt gacttatctt
     2581 accacactct ttatgataaa ggtgtaattt ataaatgtac agctgtaaat cttaacaaat
     2641 aaaaagaata gggagtggca aatatgcatt atttagtaac aggagcaact ggaggttttg
     2701 gtggttatgc gctggaattc ttaaaaaaga tggttccaca aaatgaaatc tatgtactag
     2761 tacgtagtga agaaaaagga gaagcactga aagaagctgg atttaatata cgtattggtg
     2821 attatgatga tttagactca atgaaagaag cgttgaaagg aatagatcga ttgctttttg
     2881 tctctggcgt tccaggaaat cgtcaagccg aacataagaa tgtagtgaag gcagcacaag
     2941 cagctggggt atcttatatc gcttatacaa gttttgcaga tgccgatcac tcgatcagtg
     3001 tattagcgcc agatcaccaa ttcactgaaa aaatgattaa ggattcaggt atttcccata
     3061 catttttacg gaataattgg tatgtagaga atgaattacc tatcattggg caggctttaa
     3121 aaactggtca attcgtttat gctgcaggaa atggaaaaac aggttgggca ttgaaacgtg
     3181 aatatgcaga agctgcagca aaagtactag tagaaagtga ctctccagaa atcttagaat
     3241 tatccggcaa tctaactgac tatgaagaat tagccaaggc attagagcgt gcgacaggta
     3301 aagagttaga aattattgaa gcaagtgatg cagcgtttgt cgaaaatcta aaagaagccg
     3361 gattccctca agaagcagct gacatgtttt tagcgatcca acatgatatt aaaaaggatc
     3421 agttagctat ttcctctgat gatttagaaa aagtattggg aaaaccatta acttctcttg
     3481 aagcagcatt aaaagaaata ttggatcagg aataatgtat aaagaggttg tgaaaaagcc
     3541 gattagtttt gagtatgaag aaaaattttg tgaaaaagct gttctgcatc aagtaataag
     3601 aagagtcaaa taaaaaatag ctcttcatat gtttcgttta gctggactta ttaccgcgga
     3661 gttggcagga gaacgccgtt tttattcgga aaaaggagct gagacaagat ttttgtctca
     3721 gctcctgttt gtttatcgat aaaaaagtct ggggaagacg atggctcagg ctttgttgga
     3781 aacagagccg attttatcat ttgcttttac atcacgtgcg ggttcgattt ctaagctttg
     3841 gactttgtcg ccatttgtga atacaacgac catatccgtg tttttgcctg cagattgaat
     3901 agcggcaaga tcaactaaag caatcaattg acctcttgcg actttttgac cttcttctac
     3961 atataaagtg aatggttcgc cttttaagtc aacagtgttg atgcccatat gaagcaagac
     4021 ttcgatacca gcatctgttt ggattccgac agcatgtttc gttgggaaaa tgtttgtgat
     4081 cgtaccagcg attggagaga agatttctcc attttctggt aatacagcat agccgtcacc
     4141 catcattttt tccgcgaata catcatctga aacttcagtg attggaatca gtttcccatt
     4201 tgcgatagcg taaatatctt gttcgatcgt ttcaccggca aatgtttctg ttttaaccac
     4261 ggtgtttgtt tgtgcaggtc gtgctgcagc accaccatgt agttttgcca tctcatctgc
     4321 aacgaattgt acttctgtac ctacgatgac ttgcgcattt tttccgtcga tgatcttcat
     4381 accaggtacg ccagtggctt tgattttatt ttgatcgatc aggcctgtat ctttgacttg
     4441 caaacgaagg cgtgtagtac agttatcgat cgaagttaca ttgtcggctc cgcctaatgc
     4501 agcgtagatt ttgcttgctt gtgccgcata tttattgtct gaattagtcg ttgcagtatc
     4561 gtcatctgaa agatctgctt cctcgcggcc aggagtcatc agatggaatt ttttgatagc
     4621 aaagttaaag ccaaagtagt aaatcactgc tgttactaat ccttggacga tcaacatcaa
     4681 tggctgattc gcaatcggat ttttcaaaga taggaagtaa tcgacaaatc cggcactaaa
     4741 ggcaaatcct gctgtccaat ggaagaatgc actcactgct aaagaaatcc cagtgaaaat
     4801 tgcatgcaag acatataatg gccaagcaac gaacataaat gaaaattcaa gtggttctgt
     4861 cacaccagta aagaatgaag caaaagctgc tgctagcatc aaggaagctg tttttgcttt
     4921 gttttctgga cgtgcatttc tgtaaatagc atatgctcct gctggaagcc cgaacatcat
     4981 gattgggaaa aatccagctt gatacattcc tgttacgcct tttgttcctt cagaagccaa
     5041 aaatttacca atatcattga ttcctgctac gtcaaaccag aacacggagt tcattgcttg
     5101 atgcaatcct gtagggatca gtaaacggtt gaagaagcca taaagacctg caccacccca
     5161 gcctaaactc aaaatgaatt tagcaaaaga aactaaagca gagtaaaccg gaggccatac
     5221 gagcagtagc actgcactga tcagcaacat gacaaaggca gccaagattg gcactagacg
     5281 cttgccgcta aagaaagata aagccatcgg taattttgct tcgtggaaac gattataaag
     5341 agctgccgca atcaatccgg caataatacc aataaatacg ttactgatct gagcaaaaga
     5401 tggatcaact gattctggtt tgatattcaa taaagtagct actgaatcag tttttaaaac
     5461 atttactgga acttcaaatg cgaccaaacc tgccaaggca gcagcacctg atttgtccac
     5521 tgacatccct agtgctaacc caacggcaaa cagcaaaggt aattgaccta aaactgcgtt
     5581 accgccagct tgtaaaaaat gagcgacaat gtcgttacta taagatgccc accagtttcc
     5641 gatccctact agtaaagcag cagcaggtaa gaccgcaact ggaagttgaa gggaacgtcc
     5701 cattcgttgt agatatgctt tcaatttttt tcctcctcat gattgttaac atttgtttgt
     5761 acgattgcgc ttcttaaacg ctcgatatgg atggccaagt aacccagttc ttctttcgtg
     5821 atcgcgagct ggtattcttt ggtcagcaac acacggattt ttttagaaat cttatagctt
     5881 tctgggtatt ttcgtttgac catttctacg atttccgtgt ctaaaacagc atattgttgc
     5941 gcatgggttc gttgtagaag tagtcgtaaa tgattcacca gtcttgaata attcagtgaa
     6001 aatggttctg aatggatatc tgtttccaat tctgattcca ctaaatggat gatgtcagat
     6061 acaatcgtca cttcacggat actgcgatgg ttattgttcc gaccgcttcg tccgctgtga
     6121 atatggattg cgatatatcc tgcttcgtca taagtatatg gaatcccaag ctcttttgtc
     6181 agatactcta ctgcccattg agcaatactg aattcatcac tgtaaagcac ttcgatttct
     6241 cttaaaagtt tgttgcggat gacgataccg ttattaatgt tctccgcaga aaaagcaatg
     6301 tggtcggtca aagcgatcaa tacatgttca ttcaactttt ccatcaaaac agtttccgca
     6361 tgatcaatga tcgtttctgc tgcaaataaa aagcgttcat caatctgatt aagtaaattt
     6421 tgcaacttga tttgaccttc tggttccatg acaaatatcc gttcgacatc acgatcaaaa
     6481 atcaaatcat ttctttttct gtcaaatcca atcccttttc caatagctac tttttcctgt
     6541 ccaccgtcat ctaccaatac tgcattttga ttaaagatct ttttgatttt catgcgcgca
     6601 ccctttttga agatttggtt ttcacgtttg ctagaccagt tgattgcggc caaacaaaaa
     6661 tagacacgaa aaacctccta gggaaaccat gttcctcaga gatttttcat gcctagtatg
     6721 atctagtcac atgaaacgaa ttattgttaa cgtaatcaat tttatataga cagttatgtt
     6781 ttgtcaattc tttttttata attatagtaa tttactggaa ttatcagaaa taaaaggaag
     6841 aaataaatta agaaacttat gttatttaat cgttggatct tttgcttatc ttattcgttg
     6901 ttaaaaagct gaaagcgaag gaaaaaaact ctacttaact gtatttctcc gttaggacat
     6961 ctaaaaattt acgagcagca ggagaaagag gctggtcttt tttccaaatg agattcagtg
     7021 aagcttgtaa tggcggatcg agtgggatga atattttttc cgtcccataa gtattgatga
     7081 tcccatctag agctaatgca ccaaaagtcc cgttatcgac catcaaagaa gcattgtaca
     7141 ataagttata tgttccgacg atcgataact gatctatgct gaaacctagc cattcagcta
     7201 gttgactgtc cactgacgtt tgccgggaaa tgatcaaagg aacagttttc agttcctgcg
     7261 gatggatgac ggtttgcttt gctaaaggat gatttcgatg tatcaaaagt ccccaacgat
     7321 cttgggctgg cagtcgaaat gactggtatt tttgtttgtt tgtcggttcg attacgagtc
     7381 caaaatcaag taatccgcta tccagtttgt ctatgatatc atctgcattc ccgctatata
     7441 aatgaaactg gatatcagga tgcgccttga tcaacgaatg aaggctatca gaaatgaaag
     7501 agattgcttt agtttcgcct ccgccaatgt agatttctcc agagatgatt gcgtcatttg
     7561 ttaaattgtt cgccgttttt tctaccaacg acaagatttc ttttcctttt gaataaagat
     7621 atcgaccaga atccgtcaac tgtatctctc gggagccccg agtgaaaagt gtcacaccaa
     7681 gttcttcttc taaatctttc agttgttttg agagagtagg ttgcgtgata tgcagagatt
     7741 ttgctgctcg gctgatattt ttttctctag ctactgctaa aaaatacgtc agtatacgaa
     7801 tatccatttt ttccctcctg tttttaaaaa agcataccac taagtatagt taaaaggaat
     7861 agttaagtat gttttataag tattagacat gataagccgt ccgttataaa gtaaggataa
     7921 aaggagggag caaaatgaca agcctcatcg aaaaacaaat cgtcaataaa gagattcgag
     7981 taacggatcc gctctttgaa gtgatccatc agatccaagc tgaaaacgaa gagcctttag
     8041 cagcgctgaa tactgggtac catgaaccag cagatatccg caaacggcta gaaaatatca
     8101 ttagtgacaa agtagatgat acggtgactg ttctgctgcc tttttataca gatttcggca
     8161 aacatattag tatagggaaa aatgtcttta tcaatcgtca agtgatgttc gttgacttag
     8221 gtggcatctg tttagaagat tcagtattga ttggtcctcg tgtcaacctc atcacggtga
     8281 accatctaac cgatccaaaa gaacgaagag gcttgtcagt aaagccaatc cacatcaaga
     8341 aaaatgcttg gatcggagca ggagcaacta ttctgccagg cgtaacgatt ggcgagaatg
     8401 ccattgttgc agcgaatgca actgttacga aagatgtccc agacaatacc atcgttgcag
     8461 gaatccctgc caaaatcgtc aaacctgtcg aacggattat ttgaacagta agatgaaata
     8521 agagatagtg agtataagca agagattttt caaaacagga ggagaataga atgaatgatt
     8581 tatcagaaaa agtgattgtc atcatgggcg cttcaagcgg aatcggtgaa gcaacaacga
     8641 agctattagc agaaaaaggg gctaaactag ttatagctgc acgccgagaa gatcgcctaa
     8701 aagcaataaa agaatcttta ccagaagctg agctatatat tcaaacagca gatgtaagag
     8761 attttgcaca agtccaagca gttatcgatt tagcgatgga aaagttcggt cgaatcgatg
     8821 tattgtacaa taatgcagga atcatgccaa ccgctccatt agttgaaggt caccgtgatg
     8881 aatggcaaaa tatgcttgat atcaacatca tgggtgtgtt aaatggaatt tccgccgtac
     8941 ttccaatcat ggaaaaacaa aaatctgggc atatcatttc aactgattct gtggcgggac
     9001 atgttgttta tcctgattcc gccgtttatt gcggaacaaa atttgctgtc cgtgcaatca
     9061 tggaaggatt acgtcaagag caacggcaaa ataacatcaa atctacgatc atctctccag
     9121 gagctgttca aactgaatta tatcaaacca tcagcgacaa aaaggctgct cttgaacttc
     9181 atgaagcgca aaaagaatgg ggattgacct ccgaagatat agcttctgct gtagcatttg
     9241 cgatagaaac gccagaccgg atgtctgtca gtaacatgat tatccgtccg acgacacagg
     9301 aagtataatc cataacggat aatatccaaa gagaattact tgttaaatag ttattcaaac
     9361 gaccatcaat ttaaggcgtg aatggagaag aatattcttc atttacgtct ttttatgtag
     9421 aaaaagcaaa ttcatcaaaa agaaacaaat gttatttaaa tatggacatt gacttgcttt
     9481 tactttttta gttacactgt tatttaggaa aagtttcata attcaaagga gaaaaaagat
     9541 gaaagcaaag aatttattat ttagcgttat tcttttagga aatctagcag ttgccaacac
     9601 aacagtgcta gctgaagaat cgacagaaac tgtcgcaact cagacatcga gttcttcaga
     9661 aacaggaatt gaaaacgata cagagagtac tttgcagtca gctactgtct cagaaaatac
     9721 aatttcaacc gaagaaccaa caactgaaac aacagaacaa acacaaaccg aagacagtac
     9781 atcagcagaa gctcagaaca atccagagaa tgcagaagaa atcacgaacc aattgacaga
     9841 tgggcaaaca ttgacacata cccatcaagc agatttgtct gaattcgaaa actatactgg
     9901 ctatgctttt tatgctcgct catctgctaa ttctcaacaa gcgttcattg atagtattgc
     9961 ctcaactgca caaagtttgg caagtgccaa tgacttatat gcatcagtca tgattgctca
    10021 agccatcgtt gaaagtggct gggggaacag tactttggct tctgccccta attacaatct
    10081 atttgggatt aaaggaagct ataatggcca atctgttacg atgcctactt cggaatatgt
    10141 gaatgggcaa tggattacgg tgaatgccgc ttttagaaaa tatccttcgt acaaagaatc
    10201 attgcaagat aacgtaacgg tattgaagac gacttctttt cagccaggcg tttactacta
    10261 ttccggtgca tggaaaagca atacgaactc ttacaaagat gctacggctt ggctaacagg
    10321 tcgttatgcc actgcgccta attatggttc tacattgaac aatgtaatcg aaacctataa
    10381 tctgacacag tatgatacag caccaacttc aacttctccg atgtatcgtc tgtataaccg
    10441 tcatacagga gaacatttat atacattgaa tgccggagaa aaaaattatc tgccaactgt
    10501 aggctgggaa tatgaaggga ttgcttggca agcaccaaac agcggacaac ctgtctaccg
    10561 tttatacaat ccttacagtg gagaccatca ttacacaatg gcacaatctg agatcaactc
    10621 tttaacaaaa atcggttggc gttatgaagg tctaagtttt tattctggtg gttccaagcc
    10681 aatttatcga ctatttaatc caaatgaaaa aactggtacc catcactata ccttgagtgc
    10741 taaggaaaga gattggctaa caccgatggg ctggagatat gaaggaatag gattttatgg
    10801 ttattaaaaa gaggtagtga aaaagctgcc ctgcatcaag tagtaagaac agccaaacaa
    10861 aaacagattt tcatgttttt tgtttggttg aacttattac cgcagatgca agtttttgaa
    10921 caccgtttac tcaaaaaagg ttgtgacaac atcttgtcat aactttttta ttactgttta
    10981 agcatactga tccaatttct aatattcgac gggattcttg caaaaggcga tttcggaaat
    11041 ttttggcggt gtaaaatttt ctactgcaga agagctatct tctatagttt gataagaatc
    11101 aataatcttg gttttagcgt tgtgctttct ttatcatttt ttccgttcat tctacaaaaa
    11161 atttcttttc tctatacttt tctattgaga gcgttttttt tattacacag ctgattcttt
    11221 gacttttttc tttttttatt ctattattga caagtcaatc gttgacgagt caattattag
    11281 aaaggaggaa attatgtctt tagaagagat tagtcacctt ttatatcaaa tcaaattagc
    11341 cgatcaaaaa atcgtccaga tctttgaaga aaatatcggt ataagtctta ctagatacga
    11401 gatcatgatg agactgaaag aagaaaatcc attgctacaa agcagtttgc aagaaaagtt
    11461 gcagattgat caaggagcag ttactcgtca tctgaaggta ttggaagcaa atggctatgt
    11521 ttcgcgtcag agaaatcctc agaacaaccg ggaagtgtat gtagcgctaa cagaaaaagc
    11581 ccagaagaaa atcgagcatt gtgaaatgga ccataaagat acaggttccg tgctatcccc
    11641 ggctttcagc gatgtagaaa tgaaacaatt tctaacactt ttagataaat tgaataccca
    11701 actttgcaat ataacaacag aaacgaaaga ggttaataat aatggaacaa aaaaatgatt
    11761 tttcaacaat tatgactggt agaagatccg ttcgcgtata tgatgaaaca tacaaaatcc
    11821 cacacgaaga aatgctggaa atgatcaaag aagcgacgac tgcaccttct tctgtcaata
    11881 tgcaaccatg gcgctttgtg gtcgctgaaa gcgaggaagc aaaagaaatc ttgcgtcctt
    11941 tgatccgttt caatacgaga caaaatgata cttcttctgc aatggtcatg atttttggcg
    12001 atatgcaatg ttacgaatat ggcgaagaaa tctataacca agcttacgaa tcagggaaga
    12061 tgccaaaaga agtcagagat caacaattag ctgcgatcat tccttattac aagagttttt
    12121 caagagaaga aatgaacgat gtagtcaaag tcgattctag cttagcggct atgcaattca
    12181 tgttagttgc gcgtgatcat ggctatgaaa caaatccaat tggtggattc gaagcagatc
    12241 agttggcaga ggcatttggt ttggataaag accgttatgt tccagttatt attttatcaa
    12301 taggaaaagc ggtagaagaa ggttacgagt ctgttcgttt agcaccagaa aagatcacta
    12361 cgttcgaata aaaggttttc agttactatt cagtagctat tgcttttttt gaatcgtgtg
    12421 tggtaaccta ataaaaaagg aggtcggaaa aatgactgca tcgatgaaat tacgtttcga
    12481 acttttgaat aacaactaaa taaattcaaa agacatgtat aaacaacaat ttcatggatg
    12541 gagtatgtcc attttttcga acgacagtag aataggtgaa agctatgaca gatttggtga
    12601 tttagtcata gttatttcgt tcagagtagg aaaagatgtg atgcagtttt tttgcaaaca
    12661 gatttttctg ctctttttta gtatcgataa ttgttgtttt acatgaaata ggagtgtaaa
    12721 acatatggaa aatttagcag taaatataac aaatctacaa gtcagctttg gcaaccagct
    12781 agaactatct attgattctc ttcgtgtcta tcagcaagat cgtataggga tcataggaga
    12841 aaatggtgtc ggtaaatcga ctttgctcaa actaatagcc ggtgaacttt ttcccgatca
    12901 tgggaaaatc caaacagaga tcaccttcaa ctacctgcct caattaacct atctcgctga
    12961 agcaaaggac ctaaatttgg aattagccag tcatttccag ttaagactgg aagaaacttc
    13021 agagcggaaa tggagcggag gggaagaacg aaagatcgag ttgatacgtc ttctttcttc
    13081 ttatgaacaa gggatgcttc tagacgagcc aacaacccat ctagatagaa aaagtattga
    13141 tcgactgatt gaagagcttc gttattatta tggtacgctg gtttttgtta gtcatgatcg
    13201 ctattttcta gatgagctag catcgaaaat ctgggaagta aaagacggag aaatccgaga
    13261 gttttcgggg aattatagtg cctatctcac ttaaaaagga attggagaaa aagactcagc
    13321 tacgagaagc agagtcgatc atgaaagaga aaaaacgatt ggaaaaatcg atccaagaaa
    13381 agaaaaaaca agcggaaaag ttggaaaaag tgtccagtaa aaagaaaaag caacaaatca
    13441 gaccggatcg gttgtcttcc tctaaacaaa aagacagtgt acaaaaagcc atccaaaaga
    13501 atgcgaaaac attagagaga agactccaaa aaataggaga aacaaccaag ccgcagcaga
    13561 tgaaacaaat ccgttttcca gtaccaaaat ctcttgaact ccacagccgc tatcccatca
    13621 tgggacaaaa tgtccaattg gaaagaagtg ggagaacatt actggtaaat ggtgattttc
    13681 agttttcttt aggtaaaaaa atcgcgattg tcggtgaaaa tggttcaggt aagacaacct
    13741 tattagaaca tatccgcaaa caaggagaag gaatccttct ctctccgaaa gtaagctttc
    13801 aagtatatca gcaaaagggt tatcaaatga catctgaaga atccatcatt cgttttgtca
    13861 tgagacaaac agagttttca gaatcgcttg tccgtagttt gctgaatcac ttagggtttg
    13921 ctcaggaaac tttgacgaaa ccgttatgta cattaagtgg gggagaagcg acccgtctga
    13981 cgattgcttt gctttttact aagccaagta atgtgttgct gttagatgaa ccgactaatt
    14041 ttattgatat ggcaacgatc gaagctttag agaagctaat gcaaatatat ccgggaacga
    14101 ttttgtttac ttctcatgat tcttactttg tcgagcgtac ggctgatgaa gtttatgaaa
    14161 taaaagggca gaaaataaaa aaagtactta cgagaaattt ttaaatgtgc tacgatgatt
    14221 ttcgtgacaa atttaaagga gtggtacaga ttgcctacaa ataaaaaaga aggaataatt
    14281 tttacaacaa tgatgtgttt tttgatggtc ttggggatga gcgcgtataa tttatggctg
    14341 catcaagatc ttcatttatc aagtttgttg attggtctag tgcctggatt cgtggtggct
    14401 ttcattttgg atgtcttcat catcggtgtg ctggcgaaaa aaattgcctt taaactacca
    14461 gtaaatccag aaagcaaggt ccaaatgatc ttaactattt catgcttgat ggttttagga
    14521 atggtgacat gtatgtcttt attcggtgtg atcatggaac aaggaatacc tgatcaatta
    14581 ttctctgctt atatgaatgc ttggaaaatg aatgtgattg ccgctttacc gttgcagttg
    14641 atcatcgttg gcccgctttc aagaagtgtg ctaaaagcaa ttcaaagtaa tgaatgatgg
    14701 aacactgtta tttgaaaaaa ggccttggca tgctttttgt catagtctct tgaatgcagt
    14761 tctagaaaaa tagtgatccg aacgataggt tttggcctgt cgttcggatc gctttttctt
    14821 ttccaactgt attgctcttt tattgaagat aatttgctct tcaatagata tttctagaaa
    14881 ggttctgttt atcccttact caaaaaactg ctgcatttgt tctcttactt gctgacacca
    14941 ttggagttcc tgctgacaaa gcataattct gcgctggatc acaacataac gtccaaattc
    15001 ttgtttcttg tctagcgaga ggtcattcaa ttttttttga tttttttgca tgattttgtt
    15061 cagctgttgt tctctagtga atagcagtcc agtagctgtt gttttatcga gcgtcgaaaa
    15121 agcatagatt tttgctagaa attcatcttt ttgcgtagga gcgggagttt cctctttgat
    15181 ccattcctct acaagagcac gtccttcatc agtcaagtgg tagatctttt tttgagagtg
    15241 ctcgtctttg tccaaaacgg tcacataacc ctgctggtct aacttggcaa gcgttgtata
    15301 gatctgactg tgatgggctt cccaaaaaat tgtgatcagc tgcttcaatt catacccaga
    15361 acgtggtttg gataaaagca cgcataataa tatataggct aaagtattca taaaaatcct
    15421 acctctcgtc ttattttctt tattatatca cagtaaagtt tccacgtttt acatgtgcat
    15481 atttacatgt aaaataaatc atgtatgatg ctaatagaga gaaagggatg gaaatattgg
    15541 agaatcaaat agatatacaa gaacaaacaa atgaagaaac aaaggggaaa agttcagcgc
    15601 tagttgtagc agctacctgt atgatcgctt ttatgggagt gggtctagta gacccaatct
    15661 taaaaacgat tgctgcacag ttaaacgcta cgccagctga aacgaccctg ttatttacta
    15721 gttacatgtt agtcactggt gtggtgatgc tatttacagg tttcttatct agtcggatcg
    15781 gtttgaaaaa aacattgatg acaggattgt ttatcatcgt tgtattcgct ggtcttggcg
    15841 gattatctgg gaatatcgga atgctgattg ggttacgtgc cggctggggt gtcgggaatg
    15901 ctttatttgt ctctactgct ttagcaacga tcgtcagtat tttagttggt aacacagaaa
    15961 aagcaatcat gatgtatgaa gcagcacttg gctgcggaat ggctgttggc cctctagtcg
    16021 gtggggtctt gggcagtggt tcatggcgtt atccattttt tggggtagca tttttgatgt
    16081 tttgcggttt tatagcccta gcggtacttt tacctgaaac tgagaaacca aagagaaaag
    16141 taggcctttg ggaaggtgtc aaagcgttaa gcaatcataa acttcgttca gttggactaa
    16201 tcgcattgtt atataatttc ggattcttta ctttacttgc gtatgcgcca tttttattga
    16261 ttggctattc tgaattagaa gtcggttttg tattttttgg ctggggtgtg cttctggcta
    16321 ttgcttcgat tttcgttgca ccggctcttg agcggaagtt tacgacttat cggacaattt
    16381 tagcagcatt tgtcttattc attatttgtt tgctgttatt aggagctgga acttctatgc
    16441 cagtccttgt accgatcagc attgtgttag caggattttt ccaaggaatt atcaatacac
    16501 tgttgacgac gattgctatg gaaataccag gtctgcaacg aaacgttgct tcgtccagct
    16561 atagttttgt ccgctttttc ggtggagctt tagcaccatt tattgcaggt gtgattggtg
    16621 aacatattgg tgaaagctat gcgttttatt ttgcaggtgc cattgttctt atcagtgtat
    16681 gttgtatcat ttatcaccgt aattattttg ctacaaatga agaagaataa gaaatcagag
    16741 gttgtgaaaa agctgtcctg catcaagtca taagaa
//
LOCUS       DAFBVQ010000236         7959 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.guided.092, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000236 DAFBVQ010000000
VERSION     DAFBVQ010000236.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7959)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7959)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7959
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.guided.092"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            128..1564
                     /locus_tag="LLC22_003032"
     CDS             128..1564
                     /locus_tag="LLC22_003032"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002289243.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="glycoside hydrolase family 1 protein"
                     /protein_id="HBK5436208.1"
                     /translation="MEHKELTSFPKDFLWGSASAAYQVEGAWQEDGKGESVWDRFVRI
                     PGKTFKGTNGDLAVDHYHRYKEDIALMKEQGLKAYRFSVAWTRIFPNGRGEVNQAGLA
                     FYERLIDELIENDIEPMLTLYHWDLPQALQDEYNGWESRQIIEDFTHYAETLFEAFRG
                     KVHYWISLNEQNIFTSLGYLLAAHPPGVTDPKRMYEVNHIANLANASVINKFHELEMP
                     GKIGPSFAYTPNYPIDSNPENVLAAENAEDLMANYWMDVYMWGKYPIAAMRFLEEKGW
                     APTIEAGDAELLESAKPDFLGINYYQTATNAFNPLNGVGAGKMNTTGKKGSSEETGVP
                     GMYKKVENPFVERTNWDWEIDPEGLRIGLRRITSRYRMPVLITENGLGEYDKLTEDKQ
                     IHDDYRINYLQSHVKAIKEAISDGAEVLGYCTWSYTDLLSWLNGYQKRYGFVYVDQDE
                     TQEGSLERYKKDSYYWYQKLIEENGENL"
     gene            1753..4200
                     /locus_tag="LLC22_003033"
     CDS             1753..4200
                     /locus_tag="LLC22_003033"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002344000.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="DNA translocase FtsK"
                     /protein_id="HBK5436209.1"
                     /translation="MAQKKRPTKKRKKTKKTKKQKQQQEQMLTIGVGFALILFAVFGF
                     LKLGFLGILIANGFRIIAGNTYQILCLLLAVLGFWIVIKNTEFSIGKNRRWFGGILFY
                     FGILLLLHAHLFGKLHTGEPNIMGTTWDLLASDIKQSQVDNNVGGGMIGAILYHFTYF
                     LIAQPGSYLAAVLLLAGGAFLFSNLEGYQLLNGIQSIGERVQELLEGDPAKQARKQAA
                     KEERMKQRAEAKEARRLAAKEAAEKEAAEYEKKKAVSQQRENTADEWQEPENTEPEQL
                     SFVPIDSFQENIHPANLEKPVPDTPKQTNTAEGFSDELPEDDGTSLEFEIEAEQENQD
                     YELPTVDLLDSIPTVDQSDEYKKIEKNIGVLEQTFQSFGVDAKVVKASLGPSVTKFEV
                     QPAVGVKVSKIVNLTDDIALALAAKDVRMEAPIPGKSLIGIEVPNGKISMVSFREIIE
                     AQPNHPDKLLEVPLGRDVSGRVQTADLSKMPHLLVAGSTGSGKSVAINGIITSILMRA
                     KPHEVKLMMIDPKMVELNMYNGIPHLLTPVVTNPRKAAQALQKVVQEMEERYEKFAAT
                     GVRNISGYNEFVQQKNLENGTKHPTLPFIVVIVDELADLMMVASNEVEDAIIRLAQMA
                     RAAGIHMILATQRPSVDVITGIIKANVPSRMAFAVSSGTDSRTIIDSNGAEKLLGRGD
                     MLFLPMGENKPIRVQGAFISDHEVERVVQFVTDQQEAHYEEKMMPTDEVETTGAPEQP
                     QDELFEEAKALVVEMQTASISLLQRRFRIGYNRAARLVDELEAHGVVGPSEGSKPRKV
                     FIEQEETSETLPDDNDM"
     gene            4430..5497
                     /gene="rlmN"
                     /locus_tag="LLC22_003034"
     CDS             4430..5497
                     /gene="rlmN"
                     /locus_tag="LLC22_003034"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629547.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2503)-C(2))-methyltransferase
                     RlmN"
                     /protein_id="HBK5436210.1"
                     /translation="MEKQSIYGLTNEELINWFIENGEKKFRAAQVWEWLYQKRVSNFT
                     EMTNLSKQLIEKLSEHFIINPLKQMVVQEASDGTVKYLFELPDKNMIETVLMRQEYGL
                     SVCVTTQVGCNIGCTFCASGLLKKNRDLTAGEIVAQIMMVQHYFDERNLGERVSHVVV
                     MGIGEPFDNYDNVMDFLHIINDAKGLAIGARHITVSTSGLAHKIKEFANNGLQVNLAI
                     SLHAPNNEVRTSIMRINRSFPIEKLMEAVDEYLEKTNRRITFEYIMLNQVNDRPEHAQ
                     QLADLLKDKKKLAYVNLIPYNPVSEHDQYSRSPKADVLRFYDVLKKNGVNCVIRKEHG
                     TDIDAACGQLRSKQMKKTVAK"
     gene            complement(5690..6793)
                     /locus_tag="LLC22_003035"
     CDS             complement(5690..6793)
                     /locus_tag="LLC22_003035"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002373950.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="iron-containing alcohol dehydrogenase family
                     protein"
                     /protein_id="HBK5436211.1"
                     /translation="MSQSVFLPNYTIGTDAYEKANGIVKEYGTKVVLIGGKTALSKAE
                     NKIKVALTQEIEVVASLWYGGNSTYGNIEQLIQHESVQKADVLFAVGGGRACDTVKVI
                     GEKLAKPVFTFPTIGSNCSPVTAVCVIYNEEGVMDGLFFPSKPPVHTFIDTAIIAEAP
                     DKYLWAGIGDALSKEVESTFSARGDDLGYTDRLGIQIGKMCIDRLLTYGTQALKDSAD
                     DRPSYAIEQVVSDIIVTTGLVSVLVNNNYNSAMAHSFYYGTTVLEKMEGYLHGASVSY
                     GVLTLLMMDQQFDLFDKIYVFMKKNQLPVSLTDMNLNVTTDLEAILDKAMATNDIKHV
                     PYEITREKFKQAILDVETYHATQESQQGYKKIS"
     gene            7346..7894
                     /gene="aac(6')"
                     /locus_tag="LLC22_003036"
     CDS             7346..7894
                     /gene="aac(6')"
                     /locus_tag="LLC22_003036"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_008265821.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside N-acetyltransferase AAC(6')-Ii"
                     /protein_id="HBK5436212.1"
                     /translation="MIISEFDRNNPVLKDQLSDLLRLTWPEEYGDSSAEEVEEMMNPE
                     RIAVAAVDQDELVGFIGAIPQYGITGWELHPLVVESSRRKNQIGTRLVNYLEKEVASR
                     GGITIYLGTDDLDHGTTLSQTDLYEHTFDKVASIQNLREHPYEFYEKLGYKIVGVLPN
                     ANGWDKPDIWMAKTIIPRPNSQ"
BASE COUNT         2664 a         1359 c         1729 g         2207 t
ORIGIN      
        1 tttcttacta ctcgaaacta agcgactttt tcacaacctc ctttacatat ttttattttg
       61 ttgtggaagg ggtttcgtgt tattctaaaa gaggaacgat tgaaggttat aggaaaggaa
      121 gagatgaatg gaacacaaag aacttacctc atttccaaaa gattttctgt ggggctctgc
      181 ttctgcagcg tatcaagtag aaggagcttg gcaagaagat gggaaaggag aatcagtctg
      241 ggatcgattt gtacggatac ctggaaagac atttaaagga acgaacggtg atttggcagt
      301 agaccactat catcgttata aagaagatat tgctttaatg aaagaacaag gtctgaaagc
      361 ttaccgcttc tctgtagctt ggacacggat ttttcctaat ggacgaggag aagtcaatca
      421 agctgggctc gctttttatg agagattgat cgacgaattg attgaaaacg atattgaacc
      481 tatgttgact ttatatcatt gggatcttcc acaagcattg caagatgaat ataatggttg
      541 ggaatcacgt cagatcattg aagatttcac tcattatgca gaaacattat ttgaggcatt
      601 ccgcgggaaa gtccattact ggattagttt gaatgaacaa aatatcttca cttcattagg
      661 ttatttgtta gcagcacatc cgccaggtgt gacagacccg aaacgaatgt atgaagttaa
      721 ccatattgct aatttagcaa atgcatctgt catcaataaa tttcacgagt tagaaatgcc
      781 tggaaaaatc ggaccaagct ttgcgtatac gccaaattat ccaattgaca gtaatcctga
      841 aaatgttctg gctgctgaaa atgcagaaga cctgatggcc aattattgga tggatgtcta
      901 tatgtgggga aaatatccga ttgctgccat gaggttctta gaagaaaaag gatgggcacc
      961 aacgattgaa gctggcgatg cagaattgct agaatctgct aaaccagatt ttcttgggat
     1021 caattactat caaacggcga cgaatgcatt caatccatta aacggagttg gtgctggaaa
     1081 aatgaatacg acaggaaaaa aaggttcatc agaagaaact ggagttcctg gaatgtataa
     1141 aaaagttgag aatccatttg tcgaacgaac aaattgggac tgggagattg acccagaagg
     1201 attaaggatc ggactgcgtc gtatcacaag ccgttaccgc atgccggtac tgattacgga
     1261 aaatggctta ggagagtatg acaagttgac agaagataaa caaatccatg acgactatcg
     1321 aatcaattac ttacaaagcc acgtcaaagc catcaaagaa gcaatttcgg atggagcaga
     1381 agtcctaggc tattgcacct ggtcttatac agatttgctt agctggctga acggttatca
     1441 aaagcgatat ggatttgtat atgttgatca agacgaaaca caagaaggat ctttggaacg
     1501 atataagaaa gacagttatt actggtacca aaaactgatt gaagaaaatg gagagaacct
     1561 ttagttcaca tacttaaaac aagaaggtac ggctggatat ggccgtgcct tttcttgata
     1621 aaatcattta gaaattaaga aaaactgtaa aataagctga aaaatgaaag aaagcgtcag
     1681 ttctttcaaa caaaacttta gttcccttac ttttttttgt ataatgaaac ttgatgaaat
     1741 gagggataat aaatggcaca aaagaaacgg cctactaaaa aaaggaaaaa gacgaaaaaa
     1801 acgaaaaagc aaaaacagca gcaggaacaa atgctgacga ttggtgttgg gtttgccttg
     1861 attttatttg ctgtcttcgg ctttttaaaa ttaggttttt taggaatatt gattgcaaac
     1921 ggctttcgga tcattgcagg aaatacttac caaatcctct gtcttttatt agccgtatta
     1981 ggattttgga ttgtcattaa gaatacagag ttttcaattg gtaaaaaccg acgctggttt
     2041 ggcggcatac tcttttattt cggtatctta ttattgttac atgcccattt atttggcaaa
     2101 ctccatactg gggaaccaaa tatcatgggg acgacatggg atttgttagc cagtgatata
     2161 aaacaaagtc aagtagacaa taacgttggt ggtgggatga ttggagcaat cctttatcat
     2221 tttacttact tcttgattgc acagcctgga agttatttag cagcagtgct attactggca
     2281 ggaggagcat tcctgttcag taatctggaa ggctatcagc tgttaaatgg tatccaatca
     2341 attggagaac gagtacagga attattggaa ggtgatcctg ccaagcaagc tcgaaagcaa
     2401 gcggcaaagg aagagagaat gaaacagcgc gcagaagcga aagaagcaag gcgcttagct
     2461 gcaaaagaag ctgcagaaaa agaagctgca gaatatgaga agaaaaaagc ggtgagccag
     2521 caaagggaaa atactgctga tgaatggcag gaaccagaaa atacagagcc ggagcagcta
     2581 agttttgttc caatcgacag ttttcaagaa aatatccatc ctgcgaatct agagaaacca
     2641 gtaccagata caccaaaaca gaccaataca gcagaaggtt tttcagatga gttgccagag
     2701 gatgacggta cctcattaga atttgagatt gaagcagaac aggaaaatca agactatgaa
     2761 ttaccgacag ttgatttgct tgattctata ccaactgtgg atcaaagtga tgagtataaa
     2821 aaaattgaaa aaaatatcgg cgtattagaa caaactttcc aaagtttcgg tgtcgatgcc
     2881 aaggtcgtca aagccagctt aggaccatcc gtcacaaaat tcgaagtcca gccggctgta
     2941 ggggtaaaag taagtaaaat tgtgaactta acagatgata tcgcgcttgc tttagcggcg
     3001 aaagatgtcc ggatggaagc accgattcca ggtaaatcac tgattggtat tgaagtacca
     3061 aatggaaaga tcagtatggt ttcctttaga gaaatcatcg aagcacaacc aaaccaccca
     3121 gataaattac tagaagtacc tttaggacgt gatgtttctg gacgggtaca aacggctgat
     3181 ctttcgaaga tgcctcactt actcgtggct ggttcgactg gtagtgggaa gtcagtagca
     3241 attaatggga ttatcacaag tatattaatg cgtgctaagc cccatgaagt aaaactgatg
     3301 atgatcgatc cgaaaatggt tgaattgaat atgtacaacg gcatacctca tctgttgacg
     3361 ccggtcgtga cgaaccctag aaaagcagcg caagccttac aaaaagtagt acaagaaatg
     3421 gaagaacgat atgaaaaatt cgcggcaacc ggagtaagaa atatttctgg ttacaatgaa
     3481 tttgttcaac agaaaaactt ggaaaacgga acgaaacatc caaccttacc attcatcgta
     3541 gtgatcgtag atgaattagc tgatttgatg atggtagcca gcaatgaagt tgaagatgcg
     3601 attattcgtt tagcgcaaat ggctcgggca gcggggattc atatgatcct agctactcaa
     3661 cgtccaagtg tggatgttat cacaggaatc atcaaagcaa atgtaccttc cagaatggca
     3721 tttgcggtat caagcggtac agattctcgg acgatcattg attctaatgg ggcagaaaag
     3781 ctcttagggc gaggagatat gctattcttg ccaatgggtg agaataaacc gatccgtgtg
     3841 caaggagcat tcatttctga ccacgaagta gaacgggtcg ttcaatttgt tacagatcag
     3901 caagaagctc attatgaaga gaaaatgatg ccgacagatg aagttgaaac gacaggtgct
     3961 ccagaacagc cacaagatga gctgtttgaa gaagcaaaag cacttgtcgt tgaaatgcaa
     4021 acggcaagta tttcccttct ccaaagaaga tttcggatcg gttacaaccg agcagcacgt
     4081 ttagtagatg aactggaagc tcatggagtt gttggcccgt cagaaggaag caagcctcgg
     4141 aaagtattca ttgagcagga agaaacatca gaaacgttgc cggacgataa tgacatgtaa
     4201 aacttgtgtg atgaagggtt gaaaaacgaa taaccaataa aaagacaagg catgatgata
     4261 ccaaaagaaa aaatggtttt tttccatctt ttctaatacg gtatgatgtc ttgtcttttt
     4321 agtttttgtg agattaaagt tctattcgat ttatttgtga agtattgcat taaggaaatg
     4381 aatcatgtat agtatgtagc gaaactttga gaaaaagagg gaaaatactt tggaaaaaca
     4441 gtccatttat ggcttgacga atgaagaatt aatcaattgg tttatagaaa acggcgagaa
     4501 aaaattccga gctgcccaag tttgggaatg gttgtatcaa aaacgtgtaa gtaatttcac
     4561 agaaatgacg aatctatcga aacaattgat cgaaaaatta tcggagcatt ttatcatcaa
     4621 tcctctaaaa cagatggtcg tccaagaagc ttcggatggt acagtaaaat atttgtttga
     4681 actccctgat aaaaacatga ttgagactgt actgatgaga caagaatatg gcttgtcagt
     4741 ttgtgtgacg acacaagtag gatgtaatat cggctgtacg ttttgtgcaa gcgggctgct
     4801 caaaaagaac cgtgatctga ctgctggaga aattgttgca cagatcatga tggtccaaca
     4861 ttattttgat gagcgcaatc ttggcgaacg cgtttcacat gtcgttgtaa tggggatcgg
     4921 tgagccattt gataattacg acaatgtaat ggactttttg catatcatca atgatgccaa
     4981 aggattggca attggtgctc ggcacattac agtttccact agtggattag cacacaaaat
     5041 caaggaattc gctaataacg gcttgcaagt caatctggct atttccttgc acgcgccgaa
     5101 taatgaggtg cgaacatcga tcatgcggat caaccgaagt ttcccaattg agaaattgat
     5161 ggaagctgtg gatgagtatt tagagaaaac aaaccgtcga atcacgtttg aatatatcat
     5221 gttgaatcaa gtaaatgata gaccagagca tgcgcaacaa ttagcagatc tattaaaaga
     5281 taagaaaaaa ttagcatatg tcaacttgat tccatataat ccagtcagtg aacatgatca
     5341 atattctcgc agtccaaaag ctgatgtatt gagattttat gatgtattga agaaaaacgg
     5401 cgtaaactgt gtgatacgta aagaacatgg tacagatatt gatgcagctt gcggacaatt
     5461 gcgaagcaag caaatgaaaa aaacagttgc caaataatcg tatcctactc gttttttcaa
     5521 ttaccataaa aggagcagtt ttcttaatta aggaactgtt caacttaaat aagagaaaag
     5581 attctatagc gaaagctata aagctttttt tgacaagaaa aaccctcatc aagcaaagaa
     5641 atgtcctcaa tttgatgaca gcctgcttga tgggggtttt agcaattatt taactgattt
     5701 tcttatatcc ttgctggctt tcttgtgtag catgataagt ttctacgtca agaatggcct
     5761 gtttaaattt ttctcgggtg atttcataag gcacatgttt aatatcattt gttgccatgg
     5821 ctttatctaa gattgcttct aaatcggtcg tgacattgag attcatgtcg gttaacgata
     5881 ctggaagttg gttctttttc ataaacacat agattttatc aaacaaatcg aactgctgat
     5941 ccatcatcaa taaggtcagt acaccataac tgacagatgc tccgtgaagg tatccctcca
     6001 ttttttctag aacagtcgta ccgtaataga atgagtgtgc catagcagaa ttatagttat
     6061 tgttaactaa aacagaaacc aatccggtag taacaatgat atccgaaacg acttgttcaa
     6121 ttgcatatga gggacgatcg tcggcactat ctttcaatgc ttgcgtacca taagtcaaga
     6181 gacgatcaat gcacattttt ccgatttgga ttcctaatct atccgtgtag cctagatcat
     6241 cgccacgagc agaaaaagta gattcgactt ctttggataa agcatcgcca atacctgccc
     6301 ataagtattt atcaggtgct tcggcaataa ttgctgtatc aatgaaggtg tgtacaggtg
     6361 gttttgaagg aaagaagagt ccgtccatta cgccttcttc gttatagatg acacataccg
     6421 cagtgacggg cgaacagttc gaaccaatag tgggaaaggt gaagactggt ttagctagtt
     6481 tttcaccaat gacttttaca gtatcgcaag cacggccacc accgactgca aacaggacgt
     6541 ctgctttttg gacactttca tgctggatca actgttcaat atttccataa gttgaattac
     6601 ccccgtacca gagactggcg acaacctcta tttcctgtgt caaagctact tttattttgt
     6661 tttctgcctt tgaaagtgca gtcttccctc caatcagcac tacttttgtc ccatattctt
     6721 tgacgattcc atttgctttt tcatacgcat ctgttccaat ggtataattt ggtaagaaaa
     6781 cactttgact catattcatt tccttctttc ttcgttgaaa cgggttaaaa ttttaaagag
     6841 tgatcgatct gactgcggct gtagatggag tagaggtgaa cctaagacag gataagtgat
     6901 gaataaggtg gcatgaacac cttgaaatca tcaataagta tcctaaaaac gaacaagtac
     6961 aaaaacattg aaaacgacaa taatgaattt ttgttcctct tagtatttct accgattccc
     7021 tttgcttttt tgtaattatc taaaaattct aaaaattaag attattatat gaaaacaggt
     7081 tttatttgtc aattcataat tggttttttt taaagcaaaa gataatctat atcatgatga
     7141 acaaacagag ttttttcctc caattgatgg ctttcctgat ctttcctatt ttgaataaag
     7201 tgtttctgta taattttttt attttataag taagataaat aatgaaagaa tagagatact
     7261 gattggtagc taaagatttt tgagcgagaa catttcgttt tttcaaaagg actgttagaa
     7321 taagcaagaa caagggggaa gacgtatgat aatcagtgaa tttgaccgta ataatccagt
     7381 attgaaagat cagctttctg atttactgag actgacttgg ccggaagaat atggagacag
     7441 ctcggcagaa gaagtagaag aaatgatgaa tccagaacga atcgcggtag cagcggtaga
     7501 ccaagatgag ttagtaggat ttattggtgc aatccctcaa tacggtatca caggttggga
     7561 attgcatcca ttagttgtag aaagctcccg acgaaagaac caaataggta ctcgattagt
     7621 caattactta gaaaaagaag tagcttccag aggaggaatc acgatttatt taggtacgga
     7681 tgatttagac catggaacaa cgttaagtca aacggacctg tatgagcata catttgataa
     7741 agtggcttcc atccagaacc ttcgtgaaca tccgtatgaa ttctatgaaa aattaggtta
     7801 taaaatcgta ggtgtcttac caaatgcaaa tggctgggac aaaccggata tttggatggc
     7861 aaaaacgatt attcctcgac caaattctca ataataaaaa gaggttgtga cagaagtaat
     7921 cagcttcaag aaataagaag gaatttacga aaattactt
//
LOCUS       DAFBVQ010000237         7480 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.guided.096, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000237 DAFBVQ010000000
VERSION     DAFBVQ010000237.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 7480)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 7480)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..7480
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.guided.096"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            111..194
                     /locus_tag="LLC22_003037"
     CDS             111..194
                     /locus_tag="LLC22_003037"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_001814874.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA methyltransferase attenuation leader
                     peptide"
                     /protein_id="HBK5436213.1"
                     /translation="MLVFQMRNVDKTSTVLKQTKNSDYADK"
     gene            319..1056
                     /gene="erm(B)"
                     /locus_tag="LLC22_003038"
     CDS             319..1056
                     /gene="erm(B)"
                     /locus_tag="LLC22_003038"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_011018369.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="23S rRNA (adenine(2058)-N(6))-methyltransferase
                     Erm(B)"
                     /protein_id="HBK5436214.1"
                     /translation="MNKNIKYSQNFLTSEKVLNQIIKQLNLKETDTVYEIGTGKGHLT
                     TKLAKISKQVTSIELDSHLFNLSSEKLKLNIRVTLIHQDILQFQFPNKQRYKIVGSIP
                     YHLSTQIIKKVVFESHASDIYLIVEEGFYKRTLDIHRTLGLLLHTQVSIQQLLKLPAE
                     CFHPKPKVNSVLIKLTRHTTDVPDKYWKLYTYFVSKWVNREYRQLFTKNQFHQAMKHA
                     KVNNLSTVTYEQVLSIFNSYLLFNGRK"
     gene            1226..1486
                     /locus_tag="LLC22_003039"
                     /pseudo
     CDS             1226..1486
                     /locus_tag="LLC22_003039"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000108743.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing N-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="topoisomerase DNA-binding C4 zinc finger
                     domain-containing protein"
     gene            1649..2314
                     /locus_tag="LLC22_003040"
                     /pseudo
     CDS             1649..2314
                     /locus_tag="LLC22_003040"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_086558228.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="IS1182-like element IS1182 family transposase"
     gene            2350..2595
                     /locus_tag="LLC22_003041"
     CDS             2350..2595
                     /locus_tag="LLC22_003041"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000567888.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="single-stranded DNA-binding protein"
                     /protein_id="HBK5436215.1"
                     /translation="MIDVNELLEEAIRETENLNDGEVFLVKDLFKGYVGNRIPRKDRL
                     LLGTLFLNHVSKMNGNLKAIEKTSSNQQRYKKTIDKF"
     gene            2698..3567
                     /locus_tag="LLC22_003042"
     CDS             2698..3567
                     /locus_tag="LLC22_003042"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002328890.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="nucleotidyltransferase domain-containing
                     protein"
                     /protein_id="HBK5436216.1"
                     /translation="MVDNIIKSVAEKLSSLSYIEGIVLGGSRARGTHTEDSDIDIGIY
                     YNSESFDINTINQFATKLDDEHRNNLVVPPGAWGDWINGGGWLVINGYHVDLILRDIK
                     RVEQIMKDTEHGIVTANYQTGHPHGYISAMYRGELAISKILYAKNESLCELKKQAETY
                     PNALQKSLVNFFMFEAGFSLMFVKANSGTDDKYYIAGHVFRIVSCLNQVLFACNNAYC
                     INEKKAIKLLETFEHKPEKYTEKVNHIFEVLGISLFECYDMTEKLYNEVNEIVSEINN
                     FLNEESSDERKQI"
     gene            3548..4282
                     /locus_tag="LLC22_003043"
     CDS             3548..4282
                     /locus_tag="LLC22_003043"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016250180.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="class I SAM-dependent methyltransferase"
                     /protein_id="HBK5436217.1"
                     /translation="MKENKYDDNIFFQKYSQMSRSQKGLAGAGEWETLKKMLPDFKGK
                     RVLDLGCGYGWHCIYAMENGASSVVGVDISHKMLEVAKGKTHFPQIEYECCAIEDVDF
                     PEESFDVILSSLAFHYVADYENLIKKIYRMLKAGGNLVFTVEHPVFTAHGTQDWYYNE
                     KGEILHFPVDNYYYEGKRTAMFLEEKVTKYHRTLTTYLNTLLSNSFIINQIVEPQPPE
                     NMMDIPGMADEMRRPMMLIVSAKKKM"
     gene            4315..5223
                     /locus_tag="LLC22_003044"
     CDS             4315..5223
                     /locus_tag="LLC22_003044"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491779.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside nucleotidyltransferase ANT(6)-Ia"
                     /protein_id="HBK5436218.1"
                     /translation="MRSEKEMMDLVLSLAEQDERIRIVTLEGSRANINIPKDEFQDYD
                     ITYFVSDIEPFISNDDWLNQFGNIIMMQKPEDMELFPPEEKGFSYLMLFDDYNKIDLT
                     LLPLEELDNYLKGDKLIKVLIDKDCRIKRDIVPTDIDYHVRKPSAREYDDCCNEFWNV
                     TPYVIKGLCRKEILFAIDHFNQIVRHELLRMISWKVGIETGFKLSVGKNYKFIERYIS
                     EDLWEKLLSTYRMDSYENIWEALFLCHQLFRAVSGEVAERLHYAYPEYDRNITKYTRD
                     MYKKYTGKTGCLDSTYAADIEERREQ"
     gene            5220..5762
                     /gene="sat4"
                     /locus_tag="LLC22_003045"
     CDS             5220..5762
                     /gene="sat4"
                     /locus_tag="LLC22_003045"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_000627290.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="streptothricin N-acetyltransferase Sat4"
                     /protein_id="HBK5436219.1"
                     /translation="MITEMKAGHLKDIDKPSEPFEVIGKIIPRYENENWTFTELLYEA
                     PYLKSYQDEEDEEDEEADCLEYIDNTDKIIYLYYQDDKCVGKVKLRKNWNRYAYIEDI
                     AVCKDFRGQGIGSALINISIEWAKHKNLHGLMLETQDNNLIACKFYHNCGFKIGSVDT
                     MLYANFENNFEKAVFWYLRF"
     gene            5855..6649
                     /locus_tag="LLC22_003046"
                     /note="aph(3')-IIIa"
     CDS             5855..6649
                     /locus_tag="LLC22_003046"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032491780.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="aminoglycoside O-phosphotransferase
                     APH(3')-IIIa"
                     /protein_id="HBK5436220.1"
                     /translation="MAKMRISPELKKLIEKYRCVKDTEGMSPAKVYKLVGENENLYLK
                     MTDSRYKGTTYDVEREKDMMLWLEGKLPVPKVLHFERHDGWSNLLMSEADGVLCSEEY
                     EDEQSPEKIIELYAECIRLFHSIDISDCPYTNSLDSRLAELDYLLNNDLADVDCENWE
                     EDTPFKDPRELYDFLKTEKPEEELVFSHGDLGDSNIFVKDGKVSGFIDLGRSGRADKW
                     YDIAFCVRSIREDIGEEQYVELFFDLLGIKPDWEKIKYYILLDELF"
     gene            6925..7467
                     /locus_tag="LLC22_003047"
     CDS             6925..7467
                     /locus_tag="LLC22_003047"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002321977.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="HTH domain-containing protein"
                     /protein_id="HBK5436221.1"
                     /translation="MNRINRVTSILIQLQSKKIIPAKEIAQRFNISLRTVYRDIRTLE
                     EAGIPIGSEAGKGYFLVEGFLLPPVMFTAAEVGALITAGKFLNCHGDESFIKDFDSAM
                     YKIKSILKHGEKNYAQELENSINVYSTSGQKNTLADNVIAAIQTAICNKRVISIQYPA
                     SGGQEPESRMIEPVLLQSFK"
BASE COUNT         2621 a         1131 c         1567 g         2161 t
ORIGIN      
        1 ccttatttga tagtagattt aaaactttgc aacagaacca ttttgtgtat aataggaatt
       61 gaagttaaat tagatgctaa aaatttgtaa ttaagaagga gggattcgtc atgttggtat
      121 tccaaatgcg taatgtagat aaaacatcta ctgttttgaa acagactaaa aacagtgatt
      181 acgcagataa ataaatacgt tagattaatt cctaccagtg actaatctta tgacttttta
      241 aacagataac taaaattaca aacaaatcgt ttaacttctg tatttattta cagatgtaat
      301 aacttcagga gtgattacat gaacaaaaat ataaaatatt ctcaaaactt tttaacgagt
      361 gaaaaagtac tcaaccaaat aataaaacaa ttgaatttaa aagaaaccga taccgtttac
      421 gaaattggaa caggtaaagg gcatttaacg acgaaactgg ctaaaataag taaacaggta
      481 acgtctattg aattagacag tcatctattc aacttatcgt cagaaaaatt aaaactgaac
      541 attcgtgtca ctttaattca ccaagatatt ctacagtttc aattccctaa caaacagagg
      601 tataaaattg ttgggagtat tccttaccat ttaagcacac aaattattaa aaaagtggtt
      661 tttgaaagcc atgcgtctga catctatctg attgttgaag aaggattcta caagcgtacc
      721 ttggatattc accgaacact agggttgctc ttgcacactc aagtctcgat tcagcaattg
      781 cttaagctgc cagcggaatg ctttcatcct aaaccaaaag taaacagtgt cttaataaaa
      841 cttacccgcc ataccacaga tgttccagat aaatattgga agctatatac gtactttgtt
      901 tcaaaatggg tcaatcgaga atatcgtcaa ctgtttacta aaaatcagtt tcatcaagca
      961 atgaaacacg ccaaagtaaa caatttaagt accgttactt atgagcaagt attgtctatt
     1021 tttaatagtt atctattatt taacgggagg aaataattct atgagtcgct tttttaaatt
     1081 tggaaagtta cacgttacta aagggaatgg agataaatta ttagatatac tactgacagc
     1141 ttccaagaag ctaaagaggt ccctagcgcc tacggggaat ttgtatcgat aaggggtaca
     1201 aattcccact aagcgctcgg gaccccttgt aggaaaatgt cctaagtgtg gcaacaatat
     1261 tgtattaaaa aaatcgtttt atggttgttc aaattatcct gaatgtaagt ttactttagc
     1321 tgaacatttt agaaagaaaa aactaaccaa aacgaatgta aaagaattac tggagggaaa
     1381 agaaaccctg gtaaaaggaa tcaaaaacaa agagaaaaag ccctacaatg ccgttgtaaa
     1441 aattggggaa aagggatata ttgattttat ctctttttca aaataaacat ggggctgacc
     1501 caaaagtagc tcctatatga aaaatagagg tctttccatt tagatagtag tggaaagacc
     1561 tctatttatc ttttgaaagt gaatacaaaa ataaagcaca ctctgctata atataggtga
     1621 ttaatccatt tgagagaggt gctttatcat gtatcaaaat tataccataa accaactttg
     1681 tttgcctata gatcttgaaa ttaaattgga agaaaatgat tttgctcatg ccattgtgca
     1741 gtttgttgac tctattcccg atgaagtctt tcttccttat tatcaatcta tgggtagacc
     1801 ccaatatcat cctcgtatgc tactttccat tattctttgt gcctatattc aaggggttta
     1861 ttcgggccgc caaatacaaa atatgctgat agatagtatt cggatgcgct acttatctca
     1921 agagcaattc cctaactttc gtactattaa tcgttttcgc gttcatccga ttatgaacga
     1981 tattctagat cattcatttg ttcaatttcg tgagctactg gttcaaagtg gcttaatcag
     2041 tggcagtgct ctatacattg atggtacaaa aattgaagcg gatgcgaata aatactcttt
     2101 cgtttggaaa aaaagtattt taaagtataa ggatagcctt gatcaaaaag cccttgaaaa
     2161 ctaccaacaa atggtggaaa caaaaatctt acctgagtta atagatgatt taaaggatga
     2221 actttctata gaagagattg aaaggattcg tcaatctttg gaagaaaagg aaaatcaatt
     2281 aattgaagcg attgaccaaa ccgaaacagt agaagggggc tgacccatta ttaataagga
     2341 gtggacaaca tgattgatgt aaatgagcta ttggaagaag ctattagaga aactgaaaat
     2401 ctaaatgatg gcgaagtttt tcttgttaaa gatttattca agggatatgt ggggaatagg
     2461 atacccagaa aggatcgact tctgcttgga acgttatttt taaaccatgt tagcaaaatg
     2521 aatggtaatt taaaggctat tgaaaagact tcatctaatc agcagaggta taaaaagaca
     2581 attgataagt tttaactatc ttttgtgaaa ttaaaaaaat tataaatatg ttgagtagaa
     2641 gcaaaagatt tggcttggaa tttttacagc agtgaatcga taaaaggagc atgcttgatg
     2701 gtagataata ttattaaatc agtagcagag aaattatcct ctctgtctta tatagaaggt
     2761 attgttttag gtggttcacg tgcaaggggc acccatacag aggattcgga tatagatatc
     2821 ggcatctatt acaattcaga atcatttgac ataaatacta ttaatcaatt cgctacaaag
     2881 ctggatgatg agcatagaaa taaccttgtt gtacctcccg gagcatgggg tgattggatt
     2941 aatggcggcg gatggttagt cataaacggg tatcatgtgg atttaatttt acgtgatatt
     3001 aaacgtgtgg aacaaataat gaaagataca gagcacggaa ttgttactgc caattatcag
     3061 actgggcatc cccatggtta tattagtgca atgtatcgag gagaattagc gattagcaaa
     3121 atactatatg ctaagaatga aagcttatgc gaattaaaaa aacaggcaga aacttatccc
     3181 aatgctttgc agaaaagttt agttaacttt tttatgtttg aagcagggtt ctctttaatg
     3241 tttgtaaaag caaattcggg aacagacgat aaatattata ttgcgggtca tgtttttcgt
     3301 atagtttcat gtttaaatca agtgttattt gcatgtaata atgcttattg tatcaacgaa
     3361 aagaaagcta taaaactgct tgaaactttt gaacataaac ctgaaaaata taccgagaag
     3421 gtaaatcata tttttgaagt actcggtatc tcactttttg aatgctacga catgaccgag
     3481 aagctttata atgaagtgaa tgaaattgta tcggagataa ataacttttt aaacgaggag
     3541 agttcagatg aaagaaaaca aatatgatga taatatattt tttcaaaaat acagtcaaat
     3601 gagtcgctcg cagaaaggac tggctggtgc gggagaatgg gagactttga aaaagatgct
     3661 acctgatttt aagggtaagc gtgtgcttga tttaggatgc ggctatggat ggcactgtat
     3721 atatgcgatg gaaaacggtg cttcctctgt agtaggtgtt gatatttctc ataaaatgct
     3781 cgaagtagca aaaggaaaaa cccattttcc acagattgaa tatgaatgct gtgccataga
     3841 agatgtggat ttcccagagg agagctttga tgtaatacta agttcgcttg cgtttcatta
     3901 tgtagcagac tatgagaatt taataaaaaa gatatatagg atgctgaagg ctggtggcaa
     3961 tttagttttt acagttgaac atcctgtttt tactgctcat ggaacacaag actggtatta
     4021 taacgaaaaa ggagaaatac tgcatttccc ggtggacaat tattattatg agggcaaacg
     4081 gacagctatg tttttggaag aaaaggttac aaaatatcat agaacactga ccacatatct
     4141 aaatacactg ctttcaaata gttttataat aaatcagatt gtggagccac agccgccaga
     4201 gaacatgatg gatattccgg ggatggcgga tgaaatgcga cgcccaatga tgctgattgt
     4261 atcggcaaaa aagaagatgt aataatatag aaaaaataaa cgaggagtat gtaaatgaga
     4321 tcagaaaaag aaatgatgga tttagtactt tctttagcag aacaggatga acgtattcga
     4381 attgtgaccc ttgaggggtc acgcgcaaat attaatatac ctaaagatga atttcaggat
     4441 tatgatatta catattttgt aagtgatata gaaccgttta tatctaatga tgactggctt
     4501 aatcaatttg ggaatataat aatgatgcaa aagccggagg atatggaatt attcccacct
     4561 gaagaaaagg gattttccta tcttatgcta tttgatgatt acaataaaat tgatcttacc
     4621 ttattgccct tggaagagtt agataattac ctaaagggcg ataaattaat aaaggttcta
     4681 attgataaag attgtagaat taaaagggac atagttccga ctgatataga ttatcatgta
     4741 agaaagccaa gcgcaaggga gtatgatgat tgctgcaatg aattttggaa tgtaacacct
     4801 tatgttatta aaggattgtg ccgtaaggaa attttatttg ctattgatca ttttaatcag
     4861 attgttcgcc atgagctgct gagaatgata tcatggaagg tcggcatcga aacaggcttt
     4921 aaattaagtg taggcaagaa ctataagttt attgaaaggt atatatccga ggatttgtgg
     4981 gagaaacttt tgtccaccta ccggatggat tcctatgaaa acatatggga agcattattt
     5041 ctatgccatc aattgttcag ggcggtatcc ggtgaggtgg cggaaaggct tcattatgcc
     5101 tatccggagt atgataggaa tataacaaaa tataccaggg acatgtataa aaaatacact
     5161 ggtaaaaccg gctgcctgga tagcacatat gccgctgata tagaagagag gcgggaacag
     5221 tgattacaga aatgaaagca gggcacctga aagatatcga taaacccagc gaaccatttg
     5281 aggtgatagg taagattata ccgaggtatg aaaacgagaa ttggaccttt acagaattac
     5341 tctatgaagc gccatattta aaaagctacc aagacgaaga ggatgaagag gatgaggagg
     5401 cagattgcct tgaatatatt gacaatactg ataagataat atatctttac taccaagacg
     5461 ataaatgcgt cggaaaagtt aaactgcgaa aaaattggaa ccggtacgct tatatagaag
     5521 atatcgccgt atgtaaggat ttcagggggc aaggcatagg cagcgcgctt atcaatatat
     5581 ctatagaatg ggcaaagcat aaaaacttgc atggactaat gcttgaaacc caggacaata
     5641 accttatagc ttgtaaattc tatcataatt gtggtttcaa aatcggctcc gtcgatacta
     5701 tgttatacgc caactttgaa aacaactttg aaaaagctgt tttctggtat ttaaggtttt
     5761 agaatgcaag gaacagtgaa ttggagttcg tcttgttata attagcttct tggggtatct
     5821 ttaaatactg tagaaaagag gaaggaaata ataaatggct aaaatgagaa tatcaccgga
     5881 attgaaaaaa ctgatcgaaa aataccgctg cgtaaaagat acggaaggaa tgtctcctgc
     5941 taaggtatat aagctggtgg gagaaaatga aaacctatat ttaaaaatga cggacagccg
     6001 gtataaaggg accacctatg atgtggaacg ggaaaaggac atgatgctat ggctggaagg
     6061 aaagctgcct gttccaaagg tcctgcactt tgaacggcat gatggctgga gcaatctgct
     6121 catgagtgag gccgatggcg tcctttgctc ggaagagtat gaagatgaac aaagccctga
     6181 aaagattatc gagctgtatg cggagtgcat caggctcttt cactccatcg acatatcgga
     6241 ttgtccctat acgaatagct tagacagccg attagccgaa ttggattact tactgaataa
     6301 cgatctggcc gatgtggatt gcgaaaactg ggaagaagac actccattta aagatccgcg
     6361 cgagctgtat gattttttaa agacggaaaa gcccgaagag gaacttgtct tttcccacgg
     6421 cgacctggga gacagcaaca tctttgtgaa agatggcaaa gtaagtggct ttattgatct
     6481 tgggagaagc ggcagggcgg acaagtggta tgacattgcc ttctgcgtcc ggtcgatcag
     6541 ggaggatatc ggggaagaac agtatgtcga gctatttttt gacttactgg ggatcaagcc
     6601 tgattgggag aaaataaaat attatatttt actggatgaa ttgttttagt acctagattt
     6661 agatgtctaa aaagctttaa ctacaagctt tttagacatc taatcttttc tgaagtacat
     6721 ccgcaactgt ccatactctg atgttttata tcttttctaa aagttcgcta gatagagttc
     6781 tatattagag atgtaaagag ttttggtgaa gaggtttgtg agtatggctt ttataaccag
     6841 ggtgcaatga gaagcactaa cagcagctag cttaagaacg cataggatat actttttatg
     6901 gaagtcacag aggaggaata aaatttgaac aggattaaca gagtaacctc tattcttatt
     6961 cagctgcaat caaaaaaaat aattcctgcc aaagaaattg cacagcgatt taatataagc
     7021 ttaaggacag tttacagaga tatccggaca cttgaagaag ccggaatacc aattggatct
     7081 gaggccggaa aaggatattt tcttgtagag ggcttcctac ttccgccggt aatgtttaca
     7141 gcggcggaag tgggtgcatt gattacagca gggaaatttt taaattgcca tggagatgaa
     7201 tcatttataa aggattttga ttcagctatg tataaaatca aatctatttt gaagcatggt
     7261 gaaaaaaact atgcacagga gttggagaac agtattaacg tgtacagcac atctggacag
     7321 aaaaatacat tggcggataa cgttattgca gcaattcaga ctgcaatctg caataaaagg
     7381 gtaatatcaa ttcaatatcc tgcatcagga gggcaagaac cggaaagcag aatgatagag
     7441 ccggttctgt tgcaaagttt taaataaaga ataaaatccc
//
LOCUS       DAFBVQ010000238         4544 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.guided.121, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000238 DAFBVQ010000000
VERSION     DAFBVQ010000238.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 4544)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 4544)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..4544
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.guided.121"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            348..1562
                     /locus_tag="LLC22_003048"
     CDS             348..1562
                     /locus_tag="LLC22_003048"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016629388.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="ammonium transporter"
                     /protein_id="HBK5436222.1"
                     /translation="MNTLPINTGDTAFMILCTAMVCLMTPGLAFFYGGLARKNNILTI
                     MSQSFLSVGITTIMWVFGGFGLAFGRDIGGVIGNPADFFLMRHVTSFPNMFHGATIPF
                     LMFFLYQLMFIVITVPLMTGAFAGRLNLKGYIILVIFWNLLIYFPVCHWIWGGGFLDQ
                     MGFRDFAGGAVIHTTAGFGSLACILTLGQRKIPLGERSQHSSLMAAAIGTGLLWFGWF
                     GFNSGGALRADEQAVNAFGSTFIALAFAMITWLIIAKVKGNGFDFVDVLTGSVAGLAA
                     ITPCAGYVEAKSAMLIGIIAGIVCHAAVDFRKKKQWDDALDVWGVHGMGGFTGTILIG
                     IFASNSHLLTNPSSWYFLGIQVIGVIITAVYAYVLTTVILKSAMHFTTITTTKEEQEE
                     GLDFFFFGNKLN"
     gene            1593..1811
                     /locus_tag="LLC22_003049"
                     /pseudo
     CDS             1593..1811
                     /locus_tag="LLC22_003049"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_016173391.1"
                     /note="incomplete; partial in the middle of a contig;
                     missing C-terminus; Derived by automated computational
                     analysis using gene prediction method: Protein Homology."
                     /pseudo
                     /codon_start=1
                     /transl_table=11
                     /product="hypothetical protein"
     gene            2230..2703
                     /gene="dfrF"
                     /locus_tag="LLC22_003050"
     CDS             2230..2703
                     /gene="dfrF"
                     /locus_tag="LLC22_003050"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303419.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="trimethoprim-resistant dihydrofolate reductase
                     DfrF"
                     /protein_id="HBK5436223.1"
                     /translation="MIGLIVARSKNNVIGKNGNIPWKIKGEQKQFRELTTGNVVIMGR
                     KSYEEIGHPLPNRMNIVVSTTTEYQGDNLVSVKSLEDALLLAKGRDVYISGGYGLFKE
                     ALQIVDKMYITEVDLNIEDGDTFFPEFDINDFEVLIGETLGEEVKYTRTFYVRKK"
     gene            2830..3486
                     /locus_tag="LLC22_003051"
     CDS             2830..3486
                     /locus_tag="LLC22_003051"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002303420.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="phage head-tail adapter protein"
                     /protein_id="HBK5436224.1"
                     /translation="MNKEWSELNKTMQAQIKKKDTYKRGIDTLLTLRSQLIQTLVSFK
                     EELCREDFNSIPFINADGYHSKTIAYSIWHIFRIEDIVVHTVINEDEQVFFAGNYQER
                     INSPIITTGNELMKQQIADFSKQLNLEELYLYIFEVWESTEKMLERLSYDELKRKIPK
                     ERKGYLESLNVVNDNEKAIWLIDYWCNKDICGLIQMPFSRHWIMHTEACLRIKNKIHS
                     "
     gene            3668..4198
                     /locus_tag="LLC22_003052"
     CDS             3668..4198
                     /locus_tag="LLC22_003052"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002347663.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=1
                     /transl_table=11
                     /product="dihydrofolate reductase"
                     /protein_id="HBK5436225.1"
                     /translation="MRKVVLFIAMSLDGYIADGNGGVAWLNGHGNDNENIDTYTEFTK
                     DIDTVLMGWNTSHQVVTELSPQEWVYNKFTTYVLTHKECNSSQQIHFTSENPVLLLER
                     LKQEAGKDIWICGGANLVQQLVSKNMIDKYYISVIPTLLGNGVRLLGNIDREIKLRLC
                     KTQTYNGITDLIYMRR"
BASE COUNT         1520 a          667 c          960 g         1397 t
ORIGIN      
        1 atagaatgat tttctatcag tcctagaaat tatagagccg aacaaatttg agaaccgtag
       61 cgacactcgc tgcggttctt ttttatatat tttatatgaa gtattcttta ttccttatga
      121 aaaaatatct ttaaaaataa aaaaagacga aaataaacgg ttttctataa aaagaagacc
      181 gtttattttt tgtctttatt tgtgtgaaaa acgaaaaaga gcacaacaca tcaagctttt
      241 attaattgtc tgtcttttat aaatgcaagt attaattcaa aaaaacagaa gaaaaaaaca
      301 actacacctt cttttatact cgtaatcgta gaaaggaggc gaaaaaaatg aatacattac
      361 ctatcaatac aggagataca gcattcatga ttttatgtac agcaatggtt tgcctgatga
      421 ctcctggtct agcttttttt tacggcggat tagcacggaa gaataatata ctaacgatca
      481 tgtctcaatc ttttctctcc gttgggataa caacgattat gtgggtattt ggtggattcg
      541 gattggcctt tggacgggat atcggcggtg ttattggaaa cccggcagat ttctttttga
      601 tgagacatgt tacaagcttc cccaacatgt ttcatggtgc aacgattcca tttttaatgt
      661 tctttcttta ccaactgatg tttatcgtga ttaccgttcc tttgatgaca ggagcttttg
      721 cagggagatt gaatttaaaa ggctatatta tacttgttat tttttggaat ctgctgattt
      781 atttccctgt ttgccactgg atatggggtg gcggattttt ggatcagatg ggatttagag
      841 atttcgctgg tggagcagtc atccacacga cagctggatt cggctcttta gcatgtatcc
      901 tcacacttgg tcaaagaaag attcctttag gagaaagaag tcagcatagc agtcttatgg
      961 cagctgctat cggtacagga ctgctttggt ttggctggtt cggttttaat tccggtggtg
     1021 cacttcgagc agatgaacaa gcagtcaatg catttggttc aacattcatc gctcttgcat
     1081 ttgcgatgat tacttggctg atcattgcaa aagtaaaagg aaatggcttt gattttgtcg
     1141 acgtactaac aggatccgtt gctggattgg cagccattac gccttgtgcc ggttatgtag
     1201 aagcaaaaag tgccatgctg attgggatca ttgcgggtat cgtctgtcat gctgctgttg
     1261 attttcgtaa aaagaaacaa tgggatgatg cacttgatgt gtggggtgtt catggcatgg
     1321 gcggattcac aggtacgatt ctgataggga tctttgcatc taacagccat ttactaacga
     1381 atccaagcag ctggtacttc ttagggattc aagtgattgg tgtcatcatt actgccgtgt
     1441 atgcctatgt gctgacaaca gtgattttaa aatcggcgat gcactttaca acgatcacta
     1501 ctacaaaaga agaacaagaa gaaggattgg actttttctt ctttggcaac aaactcaatt
     1561 gaaacaaatt caaatagaaa agaggaagat tcatgcaaca aagcaaaacg aaaattcctg
     1621 caaaaaaatt aacgttcttt ggctttttgg ctatgaccat ctcaatggtc gtttcattat
     1681 atgaatatcc cacattcgcg acctcaggct tcagcttagt atttttcttg ttattaggcg
     1741 gtttgctatg gtttatccct gtggcattgt gcgcagcaga gatggcaacg gtgaaaggat
     1801 gggaaaaagg tgtttcccaa acaaaaagat attaagaaac agcccatgtt tacctgcttg
     1861 caaacaaaag aatattgcta ctagactaag agatactaca taagtgtgtt ggtatctctt
     1921 ttttgttgcc gtgaaacagc agactatttc atttctgctt gattacctta aaacttatta
     1981 gtctatggtt tgtcaagggc ttgttgcgtg agaaatgctg aatatcaccc tttacaaaac
     2041 ataggctgat aagtaacttt tcaaaagcag aaaagaaatg gcaatgctta taacaatatg
     2101 atataatgca gatgaagaca aaaaaggaat ttgtcgagct ggttagttcg agataatttt
     2161 gagtttgtta agatgtggtg cacttgatgg aatcacaggt acgacatcat attatggagg
     2221 atgaaataga tgataggttt gattgttgcg aggtcaaaga ataatgttat aggcaagaat
     2281 ggtaatatac catggaaaat aaagggagaa caaaagcaat ttagagagtt aacaacgggt
     2341 aatgtggtta ttatggggcg aaagtcttat gaagaaatcg gtcatccgtt gcctaataga
     2401 atgaatattg ttgtttccac cacaacagag tatcaaggag ataatttagt ttcagttaaa
     2461 tcattagaag atgcattatt attggctaaa ggacgagatg tatacatatc tggtggatat
     2521 ggactattta aggaagcttt gcaaatagta gataaaatgt atatcacaga agtagattta
     2581 aatattgaag atggagatac attctttcca gaatttgata tcaatgattt tgaagttttg
     2641 ataggggaaa cacttggtga ggaagtgaaa tatacgagaa cattttatgt aaggaaaaaa
     2701 tgaattgagt aaattttgga tttagggtgt tttcataaat atattgcttt ttatgcatat
     2761 ataaattgtt gtaagacaaa ttccagtttg tatggggcga taaaatcaga atttgagaga
     2821 ggattgaata tgaataagga atggtctgaa cttaataaaa caatgcaggc acaaataaaa
     2881 aagaaagata cttataagag gggtattgat actttactta ctttacgaag tcagttaata
     2941 caaaccttag tatctttcaa agaagaatta tgcagagaag attttaactc aatccccttc
     3001 ataaacgctg atggttatca tagtaagacg attgcttatt ctatttggca tattttccgc
     3061 attgaagata tagttgtgca tacagtgata aatgaagatg aacaagtatt ttttgcaggc
     3121 aattatcaag agcgtatcaa ttcacctatc attacaacag gaaatgaact catgaaacag
     3181 cagattgcag acttttcaaa acagcttaat ctggaagaat tatatttata tattttcgaa
     3241 gtatgggaaa gcactgagaa aatgcttgaa cggttatctt atgatgaatt gaaaagaaaa
     3301 ataccgaaag aaagaaaagg atacttagaa tcgttgaatg tagtaaacga caatgaaaaa
     3361 gcaatttggc tgattgatta ttggtgtaat aaagatattt gtggactaat tcaaatgccg
     3421 ttttcaagac attggattat gcacacagaa gcctgtttgc gtataaagaa caagatacat
     3481 tcataggcaa aaatttcagt ttgtagaact aaggaaattg gaatttaagg aggaataaag
     3541 tatggttagt gattttataa gagcagcatt tccatggatt ttaatgggtt tatttgtagc
     3601 aatcagttgt tcccttatga gtaaaaaaga gaaataaatt cctgtttgta tttataaaag
     3661 agaaaaaatg agaaaagtag ttttatttat tgccatgagc cttgacggat atattgcgga
     3721 cggtaatggt ggagtagctt ggctaaatgg tcatggaaat gacaatgaaa acatcgacac
     3781 ttatacagaa tttaccaaag atatagatac tgtcttaatg gggtggaata cttctcatca
     3841 ggttgttact gaactttctc cgcaagaatg ggtatataat aaatttacaa cttatgtatt
     3901 aacacataaa gagtgcaatt cttcccaaca aattcatttt acaagtgaaa atcctgtttt
     3961 attattggaa cggctaaaac aagaagcagg aaaggatatt tggatttgtg gcggagcaaa
     4021 tcttgttcag cagttggtaa gcaaaaatat gattgataaa tattacattt ctgttattcc
     4081 tactctgtta ggaaatgggg ttcgtctttt gggcaacata gacagggaaa taaagttaag
     4141 gctttgtaaa acacagactt ataacggaat aaccgatttg atttatatgc gtagataact
     4201 agagagaaac agaaaagctg ttaaaccgac ggagcgatcc gaccacgttg gcgggaaaat
     4261 ccttaagatt tttccgccat gcttgcaagg gggcggttcg cttcggcggt tcggcgagct
     4321 tgcgagccgt tcaaagcccc cgttatctaa caaggggggc acaaaaaaca agaaacacta
     4381 tacactaaca agcggaaaac gctgtattta taaggcaaaa ccccattttt acagtagtga
     4441 tataaattgt acctatatca ctatgaaaat tgaatagtaa atatgagaaa gacagttgat
     4501 ttcaaaaaat aggctctttg tcaaatgatg ttggtaaaga gaaa
//
LOCUS       DAFBVQ010000239         1650 bp    DNA     linear   BCT 05-NOV-2021
DEFINITION  TPA_asm: Enterococcus faecium isolate P-2495
            SAMN22135102-rid13226503.guided.162, whole genome shotgun sequence.
ACCESSION   DAFBVQ010000239 DAFBVQ010000000
VERSION     DAFBVQ010000239.1
DBLINK      BioProject: PRJNA514245
            BioSample: SAMN22135102
            Sequence Read Archive: SRR16347220
KEYWORDS    WGS; Third Party Data; TPA; TPA:assembly.
SOURCE      Enterococcus faecium
  ORGANISM  Enterococcus faecium
            Bacteria; Firmicutes; Bacilli; Lactobacillales; Enterococcaceae;
            Enterococcus.
REFERENCE   1  (bases 1 to 1650)
  AUTHORS   Souvorov,A., Agarwala,R. and Lipman,D.J.
  TITLE     SKESA: strategic k-mer extension for scrupulous assemblies
  JOURNAL   Genome Biol 19 (1), 153 (2018)
   PUBMED   30286803
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1650)
  CONSRTM   NCBI Pathogen Detection Project
  TITLE     Direct Submission
  JOURNAL   Submitted (27-OCT-2021) National Center for Biotechnology
            Information, National Library of Medicine, National Institutes of
            Health, Bldg 45, Center Drive, Bethesda, MD, USA
COMMENT     The annotation was added by the assembly submitters using the NCBI
            Prokaryotic Genome Annotation Pipeline (PGAP). Information about
            stand-alone PGAP can be found here: https://github.com/ncbi/pgap/
            This draft WGS assembly was generated by running SKESA to generate
            a de-novo assembly. The de-novo assembly was then concatenated with
            contigs generated using a guided assembler using antimicrobial
            resistance genes as baits to comprehensively catalog the set of
            resistance genes in the isolate. Note, some parts of the contigs
            derived from the guided assembler may overlap de-novo contigs, and
            other guided assembler contigs. De-novo contigs can be
            differentiated from guided assembler contigs by their names , which
            include either 'denovo' or 'guided'.
            
            ##Genome-Assembly-Data-START##
            Assembly Date         :: 27-OCT-2021
            Assembly Method       :: SKESA v. 2.2
            Assembly Name         :: PDT001163065.1
            Long Assembly Name    :: NCBI Pathogen Detection Assembly
                                     PDT001163065.1
            Genome Coverage       :: 200x
            Sequencing Technology :: ILLUMINA
            ##Genome-Assembly-Data-END##
            
            ##Genome-Annotation-Data-START##
            Annotation Date                   :: 10/27/2021 21:24:03
            Annotation Method                 :: Best-placed reference protein
                                                 set; GeneMarkS-2+
            Annotation Pipeline               :: NCBI Prokaryotic Genome
                                                 Annotation Pipeline (PGAP)
            Annotation Provider               :: NCBI
            Features Annotated                :: Gene; CDS; rRNA; tRNA; ncRNA;
                                                 repeat_region
            Annotation Software revision      :: 2021-01-11.build5132
            Genes (total)                     :: 3,054
            CDSs (total)                      :: 2,986
            Genes (coding)                    :: 2,914
            CDSs (with protein)               :: 2,914
            Genes (RNA)                       :: 68
            rRNAs                             :: 2, 1, 2 (5S, 16S, 23S)
            complete rRNAs                    :: 2 (5S)
            partial rRNAs                     :: 1, 2 (16S, 23S)
            tRNAs                             :: 59
            ncRNAs                            :: 4
            Pseudo Genes (total)              :: 72
            CDSs (without protein)            :: 72
            Pseudo Genes (ambiguous residues) :: 0 of 72
            Pseudo Genes (frameshifted)       :: 40 of 72
            Pseudo Genes (incomplete)         :: 27 of 72
            Pseudo Genes (internal stop)      :: 20 of 72
            Pseudo Genes (multiple problems)  :: 14 of 72
            ##Genome-Annotation-Data-END##
FEATURES             Location/Qualifiers
     source          1..1650
                     /organism="Enterococcus faecium"
                     /mol_type="genomic DNA"
                     /submitter_seqid="SAMN22135102-rid13226503.guided.162"
                     /isolate="P-2495"
                     /isolation_source="hip,tissue"
                     /host="Homo sapiens"
                     /db_xref="taxon:1352"
                     /country="USA: Boston"
                     /collection_date="2016-04"
     gene            <1..1348
                     /locus_tag="LLC22_003053"
     CDS             <1..1348
                     /locus_tag="LLC22_003053"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_002390775.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=2
                     /transl_table=11
                     /product="bifunctional aminoglycoside N-acetyltransferase
                     AAC(6')-Ie/aminoglycoside O-phosphotransferase
                     APH(2'')-Ia"
                     /protein_id="HBK5436226.1"
                     /translation="DFILYLKLCNRTESLKKHYTEPWEDEVFRVIIEYNNVPIGYGQI
                     YKMYDELYTDYHYPKTDEIVYGMDQFIGEPNYWSKGIGTRYIKLIFEFLKKERNANAV
                     ILDPHKNNPRAIRAYQKSGFRIIEDLPEHELHEGKKEDCYLMEYRYDDNATNVKAMKY
                     LIEHYFDNFKVDSIEIIGSGYDSVAYLVNNEYIFKTKFSTNKKKGYAKEKAIYNFLNT
                     NLETNVKIPNIEYSYISDELSILGYKEIKGTFLTPEIYSTMSEEEQNLLKRDIASFLR
                     QMHGLDYTDISECTIDNKQNVLEEYILLRETIYNDLTDIEKDYIESFMERLNATTVFE
                     GKKCLCHNDFSCNHLLLDGNNRLTGIIDFGDSGIIDEYCDFIYLLEDSEEEIGTNFGE
                     DILRMYGNIDIEKAKEYQDIVEEYYPIETIVYGIKNIKQEFIENGRKEIYKRTYKD"
     gene            complement(1478..>1650)
                     /locus_tag="LLC22_003054"
     CDS             complement(1478..>1650)
                     /locus_tag="LLC22_003054"
                     /inference="COORDINATES: similar to AA
                     sequence:RefSeq:WP_032495458.1"
                     /note="Derived by automated computational analysis using
                     gene prediction method: Protein Homology."
                     /codon_start=3
                     /transl_table=11
                     /product="transposase"
                     /protein_id="HBK5436227.1"
                     /translation="KSTNLIERLNQEVRRREKIIRIFPNQTSANRLIGAVLMDLHDEW
                     IYSSRKYINFDK"
BASE COUNT          671 a          148 c          278 g          553 t
ORIGIN      
        1 ggattttatt ctttatttaa aactttgcaa cagaaccgaa tcattaaaaa aacattatac
       61 agagccttgg gaagatgaag tttttagagt aattattgaa tataacaatg ttcctattgg
      121 atatggacaa atatataaaa tgtatgatga gttatatact gattatcatt atccaaaaac
      181 tgatgagata gtctatggta tggatcaatt tataggagag ccaaattatt ggagtaaagg
      241 aattggtaca agatatatta aattgatttt tgaatttttg aaaaaagaaa gaaatgctaa
      301 tgcagttatt ttagaccctc ataaaaataa tccaagagca ataagggcat accaaaaatc
      361 tggttttaga attattgaag atttgccaga acatgaatta cacgagggca aaaaagaaga
      421 ttgttattta atggaatata gatatgatga taatgccaca aatgttaagg caatgaaata
      481 tttaattgag cattactttg ataatttcaa agtagatagt attgaaataa tcggtagtgg
      541 ttatgatagt gtggcatatt tagttaataa tgaatacatt tttaaaacaa aatttagtac
      601 taataagaaa aaaggttatg caaaagaaaa agcaatatat aattttttaa atacaaattt
      661 agaaactaat gtaaaaattc ctaatattga atattcgtat attagtgatg aattatctat
      721 actaggttat aaagaaatta aaggaacttt tttaacacca gaaatttatt ctactatgtc
      781 agaagaagaa caaaatttgt taaaacgaga tattgccagt tttttaagac aaatgcacgg
      841 tttagattat acagatatta gtgaatgtac tattgataat aaacaaaatg tattagaaga
      901 gtatatattg ttgcgtgaaa ctatttataa tgatttaact gatatagaaa aagattatat
      961 agaaagtttt atggaaagac taaatgcaac aacagttttt gagggtaaaa agtgtttatg
     1021 ccataatgat tttagttgta atcatctatt gttagatggc aataatagat taactggaat
     1081 aattgatttt ggagattctg gaattataga tgaatattgt gattttatat acttacttga
     1141 agatagtgaa gaagaaatag gaacaaattt tggagaagat atattaagaa tgtatggaaa
     1201 tatagatatt gagaaagcaa aagaatatca agatatagtt gaagaatatt atcctattga
     1261 aactattgtt tatggaatta aaaatattaa acaggaattt atcgaaaatg gtagaaaaga
     1321 aatttataaa aggacttata aagattgatt atataatata tgaaaagcta ttataaaaga
     1381 cattagtatt aaatagttta aaaaaatgaa aaataataaa ggaagtgagt caagtccaga
     1441 ctcctgtgta aaatgctata caatgttttt accatttcta cttatcaaaa ttgatgtatt
     1501 ttcttgaaga ataaatccat tcatcatgta ggtccataag aacggctcca attaagcgat
     1561 tggctgatgt ttgattgggg aagatgcgaa taatcttttc tcttctgcgt acttcttgat
     1621 tcagtcgttc aattagattg gtactcttta
//
